WorldWideScience

Sample records for c7-c8 propenyl side

  1. Biosynthesis of t-anethole in anise: characterization of t-anol/isoeugenol synthase and an O-methyltransferase specific for a C7-C8 propenyl side chain.

    Science.gov (United States)

    Koeduka, Takao; Baiga, Thomas J; Noel, Joseph P; Pichersky, Eran

    2009-01-01

    The phenylpropene t-anethole imparts the characteristic sweet aroma of anise (Pimpinella anisum, family Apiaceae) seeds and leaves. Here we report that the aerial parts of the anise plant accumulate t-anethole as the plant matures, with the highest levels of t-anethole found in fruits. Although the anise plant is covered with trichomes, t-anethole accumulates inside the leaves and not in the trichomes or the epidermal cell layer. We have obtained anise cDNA encoding t-anol/isoeugenol synthase 1 (AIS1), an NADPH-dependent enzyme that can biosynthesize t-anol and isoeugenol (the latter not found in anise) from coumaryl acetate and coniferyl acetate, respectively. In addition, we have obtained a cDNA encoding S-[methyl-14C]adenosyl-l-methionine:t-anol/isoeugenol O-methyltransferase 1 (AIMT1), an enzyme that can convert t-anol or isoeugenol to t-anethole or methylisoeugenol, respectively, via methylation of the para-OH group. The genes encoding AIS1 and AIMT1 were expressed throughout the plant and their transcript levels were highest in developing fruits. The AIS1 protein is 59% identical to petunia (Petunia hybrida) isoeugenol synthase 1 and displays apparent Km values of 145 microm for coumaryl acetate and 230 microm for coniferyl acetate. AIMT1 prefers isoeugenol to t-anol by a factor of 2, with Km values of 19.3 microm for isoeugenol and 54.5 microm for S-[methyl-14C]adenosyl-l-methionine. The AIMT1 protein sequence is approximately 40% identical to basil (Ocimum basilicum) and Clarkia breweri phenylpropene O-methyltransferases, but unlike these enzymes, which do not show large discrimination between substrates with isomeric propenyl side chains, AIMT1 shows a 10-fold preference for t-anol over chavicol and for isoeugenol over eugenol.

  2. 40 CFR 721.1725 - Benzoic acid, 3,3′-methyl-enebis [6 amino-, di-2-propenyl ester.

    Science.gov (United States)

    2010-07-01

    ... amino-, di-2-propenyl ester. 721.1725 Section 721.1725 Protection of Environment ENVIRONMENTAL...-, di-2-propenyl ester. (a) Chemical substance and significant new uses subject to reporting. (1) The..., Benzoic acid, 3,3′-methylenebis [6 amino-, di-2-propenyl ester. (2) The significant new uses are: (i)...

  3. Photosensitized cis/trans isomerization of 1-(1-propenyl)cycloalkenes

    Energy Technology Data Exchange (ETDEWEB)

    Inman, W.D.; Sanchez, K.A.J.; Chaidez, M.A.; Paulson, D.R. (California State Univ., Los Angeles (USA))

    1989-09-29

    The photosensitized cis/trans isomerization of a series of 1-(1-propenyl)cycloalkenes is reported. A plot of the photostationary state trans/cis ratio vs the sensitizer triplet energy for 1-(1-propenyl)cyclopentene shows a constant trans/cis ratio of {approx} 1.0 with high-energy sensitizers (E{sub T} > 61 kcal/mol). The plot shows one maxima at E{sub T} {approx} 55 kcal/mol with low-energy sensitizers (E{sub T} < 61 kcal/mol). This type of plot is very similar to those obtained with acyclic dienes such as piperylene. The 1-(1-propenyl)cyclohexene system shows a similar plot with high-energy sensitizers, but with low-energy sensitizers this system shows two maxima occurring at 56 and 47 kcal/mol, respectively. This double-maxima plot is rationalized by an unusually low trans/cis decay ratio for the s-cis relaxed triplet state of the 1-(1-propenyl)cyclohexene system. This double maxima is not observed in other diene systems due to a high trans/cis decay ratio for their s-cis relaxed triplet states. The photosensitized cis/trans isomerization of 2-ethylidene-10-methyl-1(9)-octalin was also studied as a model for a conformationally locked s-trans system. The 1-(1-propenyl)cycloheptene system undergoes photosensitized cis/trans isomerization, but photostationary cis/trans isomerization data could not be obtained due to a very efficient photosensitized dimerization of this diene system.

  4. Theoretical Study of Reaction Mechanism of 1-Propenyl Radical with NO

    Institute of Scientific and Technical Information of China (English)

    Xue-li Cheng; Yan-yun Zhao; Feng Li; Ren-tao Wu

    2008-01-01

    The reaction system of 1-propenyl radical with NO is an ideal model for studying the intermolecu- lax and intramolecular reactions of complex organic free radicals containing C=C double bonds. On the basis of the full optimization of all species with the Gaussian 98 package at the B3LYP/6- 311++G** level, the reaction mechanism was elucidated extensively using the vibrational mode analy- sis. There are seven reaction pathways and five sets of small molecule end products: CH2O+CH3CN, CH2CHCN+H2O, CH3CHO+HCN, CH3CHO+HNC, and CH3CCH+HNO. The channel of C3H5·+NO→IM1→TS1→IM2→TS2→IM3→TS3→CH3CHO+HCN is thermodynamically most favorable.

  5. (E-3-Methyl-6-(3-oxo-3-(thiophen-2-yl-1-propenyl-2(3H-benzothiazolone

    Directory of Open Access Journals (Sweden)

    Yordanka Ivanova

    2016-04-01

    Full Text Available The title compound, (E-3-methyl-6-(3-oxo-3-(thiophen-2-yl-1-propenyl-2(3H-benzothiazolone, was synthesized by Claisen-Schmidt condensation of 3-methyl-2(3H-benzothiazolone-6-carbaldehyde with 2-acetylthiophene in 94% yield. The structure of the target compound was confirmed using 1H-NMR, 13C-NMR, IR, MS, and elemental analysis.

  6. Allyl/propenyl phenol synthases from the creosote bush and engineering production of specialty/commodity chemicals, eugenol/isoeugenol, in Escherichia coli.

    Science.gov (United States)

    Kim, Sung-Jin; Vassão, Daniel G; Moinuddin, Syed G A; Bedgar, Diana L; Davin, Laurence B; Lewis, Norman G

    2014-01-01

    The creosote bush (Larrea tridentata) harbors members of the monolignol acyltransferase, allylphenol synthase, and propenylphenol synthase gene families, whose products together are able to catalyze distinct regiospecific conversions of various monolignols into their corresponding allyl- and propenyl-phenols, respectively. In this study, co-expression of a monolignol acyltransferase with either substrate versatile allylphenol or propenylphenol synthases in Escherichia coli established that various monolignol substrates were efficiently converted into their corresponding allyl/propenyl phenols, as well as providing proof of concept for efficacious conversion in a bacterial platform. This capability thus potentially provides an alternate source to these important plant phytochemicals, whether for flavor/fragrance and fine chemicals, or ultimately as commodities, e.g., for renewable energy or other intermediate chemical purposes. Previous reports had indicated that specific and highly conserved amino acid residues 84 (Phe or Val) and 87 (Ile or Tyr) of two highly homologous allyl/propenyl phenol synthases (circa 96% identity) from a Clarkia species mainly dictate their distinct regiospecific catalyzed conversions to afford either allyl- or propenyl-phenols, respectively. However, several other allyl/propenyl phenol synthase homologs isolated by us have established that the two corresponding amino acid 84 and 87 residues are not, in fact, conserved.

  7. Pharmacokinetics and N-acetylation metabolism of S-methyl-l-cysteine and trans-S-1-propenyl-l-cysteine in rats and dogs.

    Science.gov (United States)

    Amano, Hirotaka; Kazamori, Daichi; Itoh, Kenji

    2016-11-01

    1. Pharmacokinetics and N-acetylation metabolism of S-methyl-L-cysteine (SMC) and trans-S-1-propenyl-L-cysteine (S1PC) were examined in rats and dogs. SMC and S1PC (2-5 mg/kg) were well absorbed in both species with high bioavailability (88-100%). 2. SMC and S1PC were excreted only to a small extent in the urine of rats and dogs. The small renal clearance values (5 h) in dogs. 3. S1PC, but not SMC, underwent N-acetylation extensively in vivo, which can be explained by the relative activities of N-acetylation of S1PC/SMC and deacetylation of their N-acetylated forms, N-acetyl-S1PC/N-acetyl-SMC, in the liver and kidney in vitro. The activities for S1PC N-acetylation were similar to or higher than those for N-acetyl-S1PC deacetylation in liver S9 fractions of rat and dog, whereas liver and kidney S9 fractions of rat and dog had little activity for SMC N-acetylation or considerably higher activities for N-acetyl-SMC deacetylation. 4. Our study demonstrated that the pharmacokinetics of SMC and S1PC in rats and dogs was characterized by high bioavailability and extensive renal reabsorption; however, the extent of undergoing the N-acetylation metabolism was extremely different between SMC and S1PC.

  8. Density,Viscosity,Refractive Index,and Speed of Sound in Binary Mixtures of Pyridine and 1-Alkanols(C6,C7,C8,C10)at 303.15 K

    Institute of Scientific and Technical Information of China (English)

    ALI Anwar; TARIQ Mohd; NABI Firdosa; SHAHJAHAN

    2008-01-01

    The densities(ρ),viscosities(η),refractive indices(nD),and speeds of sound(u),of binary mixtures of pyridine with 1-hexanoi,1-heptanol,1-octanol and 1-decanol,including those of pure liquids,were measured over the entire composition range at 303.15 K and atmospheric pressure.From these experimental data,the values of excess molar volumes(VE),deviations in isentropic compressibilities(△ks),viscosities(△η),molar refractions(△Rm),apparent and partial molar volumes(Vφ,2 and V0φ,2 ),apparent and partial molar compressibilities(Kφ,2 and K0φ,2 ),of alkanols in pyridine and their corresponding deviations(△V and △K)were calculated.The variations of these parameters with composition of the mixtures suggest that the strength of interactions in these mixtures follow the order:1-hexanol 1-heptanol 1-octanol 1-decanol.All the excess and deviation functions were fitted to Redlich-Kister polynomial equation to determine the fitting coefficients and the standard deviations.

  9. Evaluation of the Effects of S-Allyl-L-cysteine, S-Methyl-L-cysteine, trans-S-1-Propenyl-L-cysteine, and Their N-Acetylated and S-Oxidized Metabolites on Human CYP Activities.

    Science.gov (United States)

    Amano, Hirotaka; Kazamori, Daichi; Itoh, Kenji

    2016-01-01

    Three major organosulfur compounds of aged garlic extract, S-allyl-L-cysteine (SAC), S-methyl-L-cysteine (SMC), and trans-S-1-propenyl-L-cysteine (S1PC), were examined for their effects on the activities of five major isoforms of human CYP enzymes: CYP1A2, 2C9, 2C19, 2D6, and 3A4. The metabolite formation from probe substrates for the CYP isoforms was examined in human liver microsomes in the presence of organosulfur compounds at 0.01-1 mM by using liquid chromatography-tandem mass spectrometry (LC-MS/MS) analysis. Allicin, a major component of garlic, inhibited CYP1A2 and CYP3A4 activity by 21-45% at 0.03 mM. In contrast, a CYP2C9-catalyzed reaction was enhanced by up to 1.9 times in the presence of allicin at 0.003-0.3 mM. SAC, SMC, and S1PC had no effect on the activities of the five isoforms, except that S1PC inhibited CYP3A4-catalyzed midazolam 1'-hydroxylation by 31% at 1 mM. The N-acetylated metabolites of the three compounds inhibited the activities of several isoforms to a varying degree at 1 mM. N-Acetyl-S-allyl-L-cysteine and N-acetyl-S-methyl-L-cysteine inhibited the reactions catalyzed by CYP2D6 and CYP1A2, by 19 and 26%, respectively, whereas trans-N-acetyl-S-1-propenyl-L-cysteine showed weak to moderate inhibition (19-49%) of CYP1A2, 2C19, 2D6, and 3A4 activities. On the other hand, both the N-acetylated and S-oxidized metabolites of SAC, SMC, and S1PC had little effect on the reactions catalyzed by the five isoforms. These results indicated that SAC, SMC, and S1PC have little potential to cause drug-drug interaction due to CYP inhibition or activation in vivo, as judged by their minimal effects (IC50>1 mM) on the activities of five major isoforms of human CYP in vitro.

  10. Thermoresponsive Poly(2-oxazoline) Molecular Brushes by Living Ionic Polymerization: Kinetic Investigations of Pendant Chain Grafting and Cloud Point Modulation by Backbone and Side Chain Length Variation

    KAUST Repository

    Zhang, Ning

    2012-04-17

    Molecular brushes of poly(2-oxazoline)s were prepared by living anionic polymerization of 2-iso-propenyl-2-oxazoline to form the backbone and subsequent living cationic ring-opening polymerization of 2-n- or 2-iso-propyl-2-oxazoline for pendant chain grafting. In situ kinetic studies indicate that the initiation efficiency and polymerization rates are independent from the number of initiator functions per initiator molecule. This was attributed to the high efficiency of oxazolinium salt and the stretched conformation of the backbone, which is caused by the electrostatic repulsion of the oxazolinium moieties along the macroinitiator. The resulting molecular brushes showed thermoresponsive properties, that is, having a defined cloud point (CP). The dependence of the CP as a function of backbone and side chain length as well as concentration was studied. © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  11. Side Effects (Management)

    Science.gov (United States)

    ... cancer care is relieving side effects, called symptom management, palliative care, or supportive care. It is important ... treat them. To learn about the symptoms and management of the long-term side effects of cancer ...

  12. Analysis of high-order aberration after both side laser in situ keratomileusis operation in treating high myopia%双面准分子激光原位角膜磨镶术治疗高度近视眼术后高阶像差分析

    Institute of Scientific and Technical Information of China (English)

    高莉; 张振华

    2012-01-01

    目的 比较双面准分子激光原位角膜磨镶术(both side lasik,BSL)和准分子激光原位角膜磨镶术(Laser in situ keratomileusis,lasik)治疗高度近视眼术后高阶像差的变化.方法 选择BSL和lasik两种术式对高度近视眼手术治疗61例,122只眼.其中,BSL手术30例,60只眼;lasik手术31例,62只眼.使用NIDEK公司生产的OPD-SCAN波前像差分析议,测量术前和术后一周、一个月和三个月暗室6~7 mm自然瞳孔直径的波前像差.结果 1 BSL和lasik两组术前总高阶像差、C7、C8和C12均方根值(RMS值)比较,均P>0.05,差异无统计学意义.2术后一周、一个月和三个月时BSL和lasik两组的总高阶像差、C7、C8和C12RMS值均较术前差异有统计学意义(P<0.01).3.术后一周、一个月和三个月BSL和lasik两组之间总高阶像差、C7、C8和C12RMS值比较,P值均>0.05差异无统计学意义.结论 BSL和lasik两种手术方法治疗高度近视眼,术后高阶像差增加幅度相近似.%Objective To compare the high-order aberration after both side laser in situ keratomileusis (BSL) and laser in situ keratomileusis (Lasik) operation in treating high myopia. Methods BSL and Lasik were both.performed in 61 (122 eyes) patients with high myopia.Among which 30 patients (60 eyes) were randomly selected as BSL group,and 31 patients (62 eyes) were selected as Lasik group.The wavefront aberration were measured in darkroom with normal pupil at preoperatively,1 week,1 month and 3 months postoperatively by OPD-SCAN object aberration apparatus produced in NIDEK company. Results The root mean square (RMS) value of high-order aberration,C7,C8 and C12 in BSL group and Lasik group were not statistically significant at preoperatively (P >0.05).The RMS value of C7,C8 and C12 in BSL group and Lasik group were statistically increased at 1 week,1 month and 3 months postoperatively (P <0.01).The RMS value of C7,C8 and C12 in BSL group and Lasik group were not significantly

  13. Synthesis and characterization of N,N-bis (2-hydroxyethyl)-2-amino-propenyl%N,N-二(2-羟乙基)-2-氨基丙烯的合成及表征

    Institute of Scientific and Technical Information of China (English)

    王学川; 任静; 强涛涛; 王晓芹

    2015-01-01

    以二乙醇胺和氯丙烯为原料,在碱性条件下,控制温度、时间和摩尔比反应生成N,N‐二(2‐羟乙基)‐2‐氨基丙烯,由核磁氢谱(1 H‐NMR)、红外光谱(FT‐IR)、元素分析、XRD表征了合成产物的结构和结晶性,用热重分析仪表征了产物的热稳定性.根据产物中叔胺的含量来确定最佳的合成工艺:反应温度为50℃,反应时间为70 min ,单体的摩尔比为n(二乙醇胺)∶n(氯丙烯)=1∶1.1,目标产物的产率可达到96%以上.%The N ,N‐bis(2‐hydroxyethyl)‐2‐amino‐propenyl was prepared by using diethano‐lamine and allyl chloride as raw materials under alkaline conditions .According to the content of the tertiary amine the best synthesis conditions were determined .The reaction temperature was 50 ℃ ,the reaction time was 70 min ,the molar ratio of monomers was n(diethanolamine)∶ n(allyl chloride) = 1∶1 .1 ,the yield of target product was above 96% .The structure and crystallinity of product was characterized by means of 1 H‐NMR spectrum (1 H‐NMR) ,infra‐red spectroscopy (FT‐IR) ,elemental analysis and X‐ray diffraction .The thermal stability of the product was characterized through thermal gravimetric analysis instrument .

  14. Working the Dark Side

    DEFF Research Database (Denmark)

    Bjering, Jens Christian Borrebye

    A few days after the terror attacks of 9/11, then Vice President Dick Cheney appeared on television with a call for “working the dark side.” While still unclear what this expression entailed at the time, Cheney's comment appears in retrospect to almost have been prophetic for the years to come...... – years where parts of the U.S. Army and intelligence community set up a rampant torture regime all across the world. Yet, the connection between a so-called “dark side,” “working” this “dark side,” and the torture that followed is not a given, but, instead, a consequence of a set of very specific legal...... boundaries and came to define what it meant to “work” the “dark side.”...

  15. Side Effects of Chemotherapy

    Science.gov (United States)

    ... Jacket Fashion Show Contact Us Side Effects of Chemotherapy Each of the chemotherapy drugs available today works in a slightly different ... few rules of thumb when it comes to chemotherapy that should always be kept in mind. Ignore ...

  16. [Psychoanalysis and Side Effect].

    Science.gov (United States)

    Shirahase, Joichiro

    2015-01-01

    A study of psychoanalysis from the perspective of side effects reveals that its history was a succession of measures to deal with its own side effects. This, however, does not merely suggest that, as a treatment method, psychoanalysis is incomplete and weak: rather, its history is a record of the growth and development of psychoanalysis that discovered therapeutic significance from phenomena that were initially regarded as side effects, made use of these discoveries, and elaborated them as a treatment method. The approach of research seen during the course of these developments is linked to the basic therapeutic approach of psychoanalysis. A therapist therefore does not draw conclusions about a patient's words and behaviors from a single aspect, but continues to make efforts to actively discover a variety of meanings and values from them, and to make the patient's life richer and more productive. This therapeutic approach is undoubtedly one of the unique aspects of psychoanalysis. I discuss the issue of psychoanalysis and side effects with the aim of clarifying this unique characteristic of psychoanalysis. The phenomenon called resistance inevitably emerges during the process of psychoanalytic treatment. Resistance can not only obstruct the progress of therapy; it also carries the risk of causing a variety of disadvantages to the patient. It can therefore be seen as an adverse effect. However, if we re-examine this phenomenon from the perspective of transference, we find that resistance is in fact a crucial tool in psychoanalysis, and included in its main effect, rather than a side effect. From the perspective of minimizing the character of resistance as a side effect and maximizing its character as a main effect, I have reviewed logical organization, dynamic evaluation, the structuring of treatment, the therapist's attitudes, and the training of therapists. I conclude by stating that psychoanalysis has aspects that do not match the perspective known as a side

  17. Working the Dark Side

    DEFF Research Database (Denmark)

    Bjering, Jens Christian Borrebye

    half—dark side—documents the making and nature of the dark side by analyzing a series of legal memos from the Department of Justice's Office of Legal Council and from the White House and concludes by relating its findings to traditional ideas about emergency action, national security, and torture....... By analyzing official reports and testimonies from soldiers partaking in the War On Terror, the dissertation's second part—dark arts—focuses on the transformation of the dark side into a productive space in which “information” and the hunt for said information overshadowed all legal, ethical, or political...

  18. Side effects of ergotamine

    NARCIS (Netherlands)

    Meyler, WJ

    1996-01-01

    Ergotamine has been used for many years in the treatment of migraine, although there is Little formal clinical evidence that it is significantly more efficacious than placebo. A number of side effects associated with ergotamine have been reported in the literature, including myocardial infarction, i

  19. Colorectal cancers choosing sides

    NARCIS (Netherlands)

    Albuquerque, Cristina; Bakker, Elvira R. M.; van Veelen, Wendy; Smits, Ron

    2011-01-01

    In contrast to the majority of sporadic colorectal cancer which predominantly occur in the distal colon, most mismatch repair deficient tumours arise at the proximal side. At present, these regional preferences have not been explained properly. Recently, we have screened colorectal tumours for mutat

  20. HIV Medicines and Side Effects

    Science.gov (United States)

    Side Effects of HIV Medicines HIV Medicines and Side Effects (Last updated 1/17/2017; last reviewed 1/17/2017) Key Points HIV medicines help people with ... will depend on a person’s individual needs. Can HIV medicines cause side effects? HIV medicines help people ...

  1. The Dark Side of Creativity

    Science.gov (United States)

    Cropley, David H., Ed.; Cropley, Arthur J., Ed.; Kaufman, James C., Ed.; Runco, Mark A., Ed.

    2010-01-01

    With few exceptions, scholarship on creativity has focused on its positive aspects while largely ignoring its dark side. This includes not only creativity deliberately aimed at hurting others, such as crime or terrorism, or at gaining unfair advantages, but also the accidental negative side effects of well-intentioned acts. This book brings…

  2. Managing Chemotherapy Side Effects: Diarrhea

    Science.gov (United States)

    ... such as Pedialyte ® ••Tea (without caffeine) ••Water ••Applesauce ••Bananas ••Crackers ••Cream of wheat or rice cereal ••Eggs •• ... has a series of 18 Chemotherapy Side Effects Sheets at: www.cancer.gov/chemo-side-effects

  3. Blind loop perforation after side-to-side ileocolonic anastomosis

    Institute of Scientific and Technical Information of China (English)

    Raffaele; Dalla; Valle; Roberto; Zinicola; Maurizio; Iaria

    2014-01-01

    Blind loop syndrome after side-to-side ileocolonic anas-tomosis is a well-recognized entity even though its in-cidence and complication rates are not clearly defined. The inevitable dilation of the ileal cul-de-sac leads to stasis and bacterial overgrowth which eventually leads to mucosal ulceration and even full-thickness perfora-tion. Blind loop syndrome may be an underestimated complication in the setting of digestive surgery. It should always be taken into account in cases of acute abdomen in patients who previously underwent right hemicolectomy. We herein report 3 patients who were diagnosed with perforative blind loop syndrome a few years after standard right hemicolectomy followed by a side-to-side ileocolonic anastomosis.

  4. Blind loop perforation after side-to-side ileocolonic anastomosis.

    Science.gov (United States)

    Valle, Raffaele Dalla; Zinicola, Roberto; Iaria, Maurizio

    2014-08-27

    Blind loop syndrome after side-to-side ileocolonic anastomosis is a well-recognized entity even though its incidence and complication rates are not clearly defined. The inevitable dilation of the ileal cul-de-sac leads to stasis and bacterial overgrowth which eventually leads to mucosal ulceration and even full-thickness perforation. Blind loop syndrome may be an underestimated complication in the setting of digestive surgery. It should always be taken into account in cases of acute abdomen in patients who previously underwent right hemicolectomy. We herein report 3 patients who were diagnosed with perforative blind loop syndrome a few years after standard right hemicolectomy followed by a side-to-side ileocolonic anastomosis.

  5. Two-Sided Tests and One-Sided Confidence Bounds

    OpenAIRE

    1994-01-01

    Based on the duality between tests and confidence sets we introduce a new method to derive one-sided confidence bounds following the rejection of a null hypothesis with two-sided alternatives. This method imputes that the experimenter is only interested in confidence bounds if the null hypothesis is rejected. Furthermore, we suppose that he is only interested in the direction and a lower confidence bound concerning the distance of the true parameter value to the parameter values in the null h...

  6. Managing Chemotherapy Side Effects: Constipation

    Science.gov (United States)

    N ational C ancer I nstitute Managing Chemotherapy Side Effects Constipation Take these steps: Eat high-fiber foods such as: ● ● Whole-grain breads and cereals ● ● Fruits and vegetables ● ● Nuts and seeds ...

  7. Novel side branch ostial stent.

    Science.gov (United States)

    Chen, Shao-Liang; Lv, Shu-Zheng; Kwan, Tak W

    2009-04-01

    Bifurcation lesions are technically challenging and plagued by a high incidence of restenosis, especially at the side branch orifice, which results in a more frequent need for revascularization during the follow-up period. This report discusses two clinical experiences with a novel side branch ostial stent, the BIGUARD stent, designed for the treatment of bifurcation lesions; procedural success with no in-hospital complications was observed in types IVb and Ia lesions.

  8. The Moon's near side megabasin and far side bulge

    CERN Document Server

    Byrne, Charles

    2013-01-01

    Since Luna and Lunar Orbiter photographed the far side of the Moon, the mysterious dichotomy between the face of the Moon as we see it from Earth and the side of the Moon that is hidden has puzzled lunar scientists. As we learned more from the Apollo sample return missions and later robotic satellites, the puzzle literally deepened, showing asymmetry of the crust and mantle, all the way to the core of the Moon. This book summarizes the author’s successful search for an ancient impact feature, the Near Side Megabasin of the Moon and the extensions to impact theory needed to find it. The implications of this ancient event are developed to answer many of the questions about the history of the Moon.

  9. Wake flow behind two side-by-side square cylinders

    Energy Technology Data Exchange (ETDEWEB)

    Yen, Shun C., E-mail: scyen@mail.ntou.edu.t [Department of Mechanical and Mechatronic Engineering, National Taiwan Ocean University, Keelung 202, Taiwan (China); Liu, Jung H. [Department of Mechanical and Mechatronic Engineering, National Taiwan Ocean University, Keelung 202, Taiwan (China)

    2011-02-15

    This study investigates the flow structures, form drag coefficients and vortex-shedding characteristics behind a single-square cylinder and two side-by-side cylinders in an open-loop wind tunnel. The Reynolds number (Re) and gap ratio (g*) are 2262 < Re < 28,000 and 0 {<=} g* {<=} 12, respectively. The flow patterns around the square cylinders are determined using the smoke-wire scheme. Experimental results indicate that the flow structures behind two side-by-side square cylinders are classified into three modes -single mode, gap-flow mode and couple vortex-shedding. The gap-flow mode displays anti-phase vortex shedding induced from the interference between the two square cylinders. However, the couple vortex-shedding mode exhibits in-phase vortex shedding that is caused by the independent flow behavior behind each square cylinder. The surface-pressure profile, form drag coefficient for each square cylinder (C{sub D}-bar) and vortex-shedding frequency were measured and calculated using a pressure transducer and a hot-wire anemometer. For two side-by-side cylinder configurations, the maximum C{sub D}-bar of 2.24 occurs in the single mode, while the minimum C{sub D}-bar of 1.68 occurs in the gap-flow mode. Additionally, the C{sub D}-bar in the coupled vortex-shedding mode is intermediate and approximately equal to that of a single (isolated) square cylinder. Moreover, the single mode has the highest Strouhal number (St) and the gap-flow mode has the lowest St.

  10. Brushless machine having ferromagnetic side plates and side magnets

    Science.gov (United States)

    Hsu, John S

    2012-10-23

    An apparatus is provided having a cylindrical stator and a rotor that is spaced from a stator to define an annular primary air gap that receives AC flux from the stator. The rotor has a plurality of longitudinal pole portions disposed parallel to the axis of rotation and alternating in polarity around a circumference of the rotor. Each longitudinal pole portion includes portions of permanent magnet (PM) material and at least one of the longitudinal pole portions has a first end and an opposing second end and a side magnet is disposed adjacent the first end and a side pole is disposed adjacent the second end.

  11. Side Effects of Side Effects Information in Drug Information Leaflets.

    Science.gov (United States)

    Maat, H. Pander; Klaassen, R.

    1994-01-01

    Describes a study in which drug information leaflets given to patients were improved in two ways, first by adding a short introductory paragraph on the nature of side effects generally, and second by adjusting frequency descriptors to more accurately reflect pretesting of the drug. Explains that participants in the study were less likely to…

  12. Running away from side effects

    DEFF Research Database (Denmark)

    Casla, S; Hojman, P; Márquez-Rodas, I

    2015-01-01

    be an integrative complementary intervention to improve physiological, physical and psychological factors that affect survival and quality of life of these patients. For that reason, the main objective of this review is to provide a general overview of exercise benefits in breast cancer patients and recommendations......The number of breast cancer survivors increases every year, thanks to the development of new treatments and screening techniques. However, patients present with numerous side effects that may affect their quality of life. Exercise has been demonstrated to reduce some of these side effects......, but in spite of this, few breast cancer patients know and follow the exercise recommendations needed to remain healthy. In this review, we describe the different breast cancer treatments and the related side effects and implications of exercise in relation to these. We propose that exercise could...

  13. A Typology of Multi-sided Platforms

    DEFF Research Database (Denmark)

    Staykova, Kalina Stefanova; Damsgaard, Jan

    2015-01-01

    which evolved several steps into being multi-sided (Facebook). Our analysis shows a structural difference between one-sided, two-sided and multi-sided platforms and that platforms consist of a core and potentially also a periphery. The sides of a platform and the ties which connect them can be arranged...

  14. Dark Side of the Universe

    CERN Document Server

    2016-01-01

    The Dark Side of the Universe (DSU) workshops bring together a wide range of theorists and experimentalists to discuss current ideas on models of the dark side, and relate them to current and future experiments. This year's DSU will take place in the colorful Norwegian city of Bergen. Topics include dark matter, dark energy, cosmology, and physics beyond the standard model. One of the goals of the workshop is to expose in particular students and young researchers to the fascinating topics of dark matter and dark energy, and to provide them with the opportunity to meet some of the best researchers in these areas .

  15. Side-View Face Recognition

    NARCIS (Netherlands)

    Santemiz, Pinar; Spreeuwers, Luuk J.; Veldhuis, Raymond N.J.; Biggelaar , van den Olivier

    2011-01-01

    As a widely used biometrics, face recognition has many advantages such as being non-intrusive, natural and passive. On the other hand, in real-life scenarios with uncontrolled environment, pose variation up to side-view positions makes face recognition a challenging work. In this paper we discuss th

  16. The DarkSide Program

    Directory of Open Access Journals (Sweden)

    Rossi B.

    2016-01-01

    Full Text Available DarkSide-50 at Gran Sasso underground laboratory (LNGS, Italy, is a direct dark matter search experiment based on a liquid argon TPC. DS-50 has completed its first dark matter run using atmospheric argon as target. The detector performances and the results of the first physics run are presented in this proceeding.

  17. The Dark Side of Management

    DEFF Research Database (Denmark)

    Hanlon, Gerard; Dunne, Stephen; Johnsen, Christian Garmann

    2017-01-01

    Towards the end of 2015, the ephemera collective organised, chaired and participated within two separate Q+A panels celebrating the launch of Gerard Hanlon’s The dark side of management: A secret history of management theory. The events took place in The University of Leicester’s School...... of Management and Copenhagen Business School’s Management, Politics and Philosophy Department. Each of the events were recorded, transcribed, edited and amalgamated into the following feature....

  18. Metabolic Side Effects of Lithium

    Directory of Open Access Journals (Sweden)

    M. Cagdas Eker

    2010-04-01

    Full Text Available Lithium is an alkaline ion being used since 19th century. After its widespread use in psychiatric disorders, observed side effects caused skepticism about its therapeutic efficacy. Despite several disadvantages, lithium is one of the indispensible drugs used in affective disorders, especially in bipolar disorder. It became a necessity for physicians to recognize its side effects since lithium is still accepted as a gold standard in the treatment of bipolar disorder. Adverse effects of chronic administration of lithium on several organ systems are widely known. In this article metabolic effects of lithium on thyroid and parathyroid glands, body mass index and kidneys will be discussed along with their mechanisms, clinical findings, possible risk factors and treatment. One of the most common side effect of lithium is hypothyroidism. It has the same clinical and biochemical properties as primary hypothyroidism and observed as subclinical hypothyroidism in the first place. Hypothyroidism, even its subclinical form, may be associated with non-response or inadequate response and is indicated as a risk factor for development of rapid cycling bipolar disorder. Therefore, hypothyroidism should be screened no matter how severe it is and should be treated with thyroid hormone in the presence of clinical hypothyroidism. Weight gain due to lithium administration disturbs the compliance to treatment and negatively affects the course of the illness. Increased risk for diabetes, hypertension, ischemic heart disease and stroke because of weight gain constitute other centers of problem. Indeed, it is of importance to determine the risk factors before treatment, to follow up the weight, to re-organize nutritional habits and to schedule exercises. Another frequent problematic side effect of lithium treatment is renal dysfunction which clinically present as nephrogenic diabetes insipidus with the common symptoms of polyuria and polydipsia. Nephrogenic diabetes

  19. Flapping propulsion with side-by-side pitching foils

    Science.gov (United States)

    Huera-Huarte, Francisco

    2016-11-01

    Fish schools are one of the most common types of collective behaviour observed in nature. One of the reasons why fish swim in groups, is to reduce the cost of transport of the school. In this work we explore the propulsive performance of two foils flapping in a symmetric configuration, i.e. with an out-of-phase flapping motion. Direct thrust measurements and Particle Image Velocimetry (PIV) allowed a detailed examination of the forces and the wake generated by the system, for different kinematics (swept angles and frequencies) and shaft separations. For certain specific cases, volumetric PIV shows major differences on how the different structures in the wake of the system evolve, depending on the imposed kinematics and the side-by-side separation between the foils. Results obtained will be compared against data produced with isolated flapping foils with similar imposed kinematics, with the aim to better understand the interactions between both and the performance of the system as a whole. The author would like to acknowledge the financial support provided by the Spanish Ministerio de Economia y competitividad (MINECO) through Grant DPI2015-71645-P.

  20. Lighter side of adaptive optics

    CERN Document Server

    Tyson, Robert K

    2009-01-01

    Adaptive optics has been under development for well over 40 years. It is an indisputable necessity for all major ground-based astronomical telescopes and is the foundation for laser and wavefront sensor design. Lighter Side of Adaptive Optics is a nontechnical explanation of optics, the atmosphere, and the technology for ""untwinkling"" the stars. While interweaving a fictional romantic relationship as an analogy to adaptive optics, and inserting satire, humor, and philosophical rants, Tyson makes a difficult scientific topic understandable. The ""why"" and ""how"" of adaptive optics has never

  1. Enter the DarkSide

    Science.gov (United States)

    Davini, Stefano

    2014-04-01

    A wide range of astrophysical measurements evidence that the stars and gas in all galaxies are immersed in a much larger cloud of non-luminous and non-baryonic dark matter. The nature of the dark matter is still totally unknown, and the resolution of the dark matter puzzle is of fundamental importance to cosmology, astrophysics, and elementary particle physics. One of the major lines of researches directing their efforts at detection of dark matter is direct searches of Weakly Interacting Massive Particles (WIMPs) with detectors operated in deep underground laboratories. The new generation of direct searches of WIMPs promises to probe the most interesting region of parameters for the dark matter candidates. I will review and describe the DarkSide-50 underground Argon detector at Laboratori Nazionali del Gran Sasso.

  2. Shortest Paths With Side Sensors

    CERN Document Server

    Salaris, Paolo; Bicchi, Antonio

    2011-01-01

    We present a complete characterization of shortest paths to a goal position for a vehicle with unicycle kinematics and a limited range sensor, constantly keeping a given landmark in sight. Previous work on this subject studied the optimal paths in case of a frontal, symmetrically limited Field--Of--View (FOV). In this paper we provide a generalization to the case of arbitrary FOVs, including the case that the direction of motion is not an axis of symmetry for the FOV, and even that it is not contained in the FOV. The provided solution is of particular relevance to applications using side-scanning, such as e.g. in underwater sonar-based surveying and navigation.

  3. The dark side of technology

    CERN Document Server

    Townsend, Peter

    2016-01-01

    Technological progress comes with a dark side where good ideas and intentions produce undesirable results (extreme downsides include atomic and biological weapons). The many and various unexpected outcomes of technology span humorous to bizarre, to situations that threaten human survival. Development can be positive for some, but negative and isolating for others (e.g. older or poorer people). Progress is often transient, as faster electronics and computers dramatically shorten retention time of data, knowledge, and information loss (e.g. even photos may be unreadable within a generation). Progress and globalization are also destroying past languages and cultures. Advances cut across all areas of science and life, and the scope is vast from biology, medicine, agriculture, transport, electronics, computers, long-range communications, to a global economy. Reliance on technology causes unexpected technology-driven vulnerability to natural events (e.g. intense sunspot activity) that could annihilate advanced soci...

  4. 49 CFR 238.217 - Side structure.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Side structure. 238.217 Section 238.217 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION... Equipment § 238.217 Side structure. Each passenger car shall comply with the following: (a) Side posts...

  5. Distributed video coding with multiple side information

    DEFF Research Database (Denmark)

    Huang, Xin; Brites, C.; Ascenso, J.;

    2009-01-01

    Distributed Video Coding (DVC) is a new video coding paradigm which mainly exploits the source statistics at the decoder based on the availability of some decoder side information. The quality of the side information has a major impact on the DVC rate-distortion (RD) performance in the same way...... the quality of the predictions had a major impact in predictive video coding. In this paper, a DVC solution exploiting multiple side information is proposed; the multiple side information is generated by frame interpolation and frame extrapolation targeting to improve the side information of a single...

  6. Car Side Structure Crashworthiness in Pole and Moving Deformable Barrier Side Impacts

    Institute of Scientific and Technical Information of China (English)

    WANG Dazhi; DONG Guang; ZHANG Jinhuan; HUANG Shilin

    2006-01-01

    To clearly understand passenger car structure's crashworthiness in typical side impacts of pole and moving deformable barrier (MDB) impact modes, which could assist the establishment of Chinese vehicle side impact safety regulations, a full midsized car finite element model, calibrated by pole side impact test, was built and the pole side impact according to European New Car Assessment Program (EuroNCAP) and the MDB side impact according to ECE R95 regulations were simulated with LS-DYNA. The accelerations and the structure deformations from simulations were compared. It can be concluded that the pole side impact focuses primarily on side structure crashworthiness as a result of large intrusions, while the MDB side impact focuses primarily on full side structure crashworthiness. Accordingly, occupant protection strategies focus on different aspects to improve side impact safety. In the pole side impact the objective is to maintain the passenger compartment and protect the passenger's head from impacting the pole, while in the MDB side impact the objective is to protect the full human body. In the design of the car side structures, at least these two tests should be considered for assessing their side impact crashworthiness. Conducting these two side impact tests as certified tests provides insights into car safety during side impacts.

  7. Physiological and skill demands of 'on-side' and 'off-side' games.

    Science.gov (United States)

    Gabbett, Tim J; Jenkins, David G; Abernethy, Bruce

    2010-11-01

    This study investigated the physiological and skill demands of 'on-side' and 'off-side' games in elite rugby league players. Sixteen male rugby league players participated in 'on-side' and 'off-side' games. Both small-sided games were played in a 40- × 40-m playing area. The 'off-side' game permitted players to have 3 'plays' while in possession of the ball. Players were permitted to pass backward or forward (to an 'off-side' player). The 'on-side' game also permitted players to have 3 'plays' while in possession of the ball. However, players were only permitted to pass backward to players in an 'on-side' position. Heart rate and movement patterns (via global positioning system) were recorded continuously throughout both games. Data were collected on the distance covered, number of high-acceleration and velocity efforts, and recovery between efforts. Video footage was also taken to track the performance of the players. Post hoc inspection of the footage was undertaken to count the number of possessions and the number and quality of disposals. In comparison to 'on-side' games, 'off-side' games had a greater number of involvements ("touches"), passes, and effective passes. However, the cognitive demands of 'on-side' games were greater than 'off-side' games. 'Off-side' games resulted in a greater total distance covered, greater distance covered in mild and moderate accelerations, and greater distance covered in low, moderate, and high-velocity efforts. There were also a greater number of short duration recovery periods between efforts in 'off-side' games. The results of this study demonstrate that 'off-side' games provide greater physiological and skill demands than 'on-side' games. 'Off-side' games may provide a practical alternative to 'on-side' games for the development of skill and fitness in elite rugby league players.

  8. Sexual side effects induced by psychotropic drugs

    DEFF Research Database (Denmark)

    Kristensen, Ellids

    2002-01-01

    The majority of psychotropic drugs entail sexual side effects. The sexual side effects may reduce quality of life and may give rise to non-compliance. For example, 30-60 per cent of patients treated with antidepressants are known to develop a sexual dysfunction. However, some psychotropic drugs...... with no or very few sexual side effects have begun to emerge. The treatment of sexual side effects induced by psychotropic drugs may consist of: modified sexual habits, reduction in dosage, switching to another medication, possibly in combination with different psychotropic agents, other varieties...

  9. 7 CFR 29.6035 - Side.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Side. 29.6035 Section 29.6035 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... INSPECTION Standards Definitions § 29.6035 Side. A certain phase of quality as contrasted with some...

  10. European side markers effect on traffic safety

    NARCIS (Netherlands)

    Roelfsema, A.; Theeuwes, J.; Alferdinck, J.W.A.M

    1999-01-01

    In 1993 new European legislation regarding side-markers for passenger cars became effective. Volvo requested the TNO-Human Factors Research Institute (HFRI) to investigate the possible safety benefit of this European side-markers configuration. A test panel at TNO- HFRI was used to determine the dif

  11. Identifying Cross-Sided Liquidity Externalities

    NARCIS (Netherlands)

    J.A. Skjeltorp (Johannes); E. Sojli (Elvira); W.W. Tham (Wing Wah)

    2013-01-01

    markdownabstract__Abstract__ We study the relevance of the cross-sided externality between liquidity makers and takers from the two-sided market perspective. We use exogenous changes in the make/take fee structure, minimum tick-size and technological shocks for liquidity takers and makers, as exper

  12. Managing Chemotherapy Side Effects: Nausea and Vomiting

    Science.gov (United States)

    ... boiled, without the skin ••White rice ••White toast ••Bananas ••Canned fruit such as applesauce, peaches, and pears •• ... has a series of 18 Chemotherapy Side Effects Sheets at: www.cancer.gov/chemo-side-effects

  13. Back-side readout semiconductor photomultiplier

    Science.gov (United States)

    Choong, Woon-Seng; Holland, Stephen E

    2014-05-20

    This disclosure provides systems, methods, and apparatus related to semiconductor photomultipliers. In one aspect, a device includes a p-type semiconductor substrate, the p-type semiconductor substrate having a first side and a second side, the first side of the p-type semiconductor substrate defining a recess, and the second side of the p-type semiconductor substrate being doped with n-type ions. A conductive material is disposed in the recess. A p-type epitaxial layer is disposed on the second side of the p-type semiconductor substrate. The p-type epitaxial layer includes a first region proximate the p-type semiconductor substrate, the first region being implanted with p-type ions at a higher doping level than the p-type epitaxial layer, and a second region disposed on the first region, the second region being doped with p-type ions at a higher doping level than the first region.

  14. A Typology of Multi-sided Platforms

    DEFF Research Database (Denmark)

    Staykova, Kalina Stefanova; Damsgaard, Jan

    2015-01-01

    exemplary cases which allow us to illustrate the platform heterogeneity and to support new MSPs typology. As examples we include a physical two-sided platform (Gatwick Airport) that adds a third side, a digital one-sided platform transformed into being two-sided (Pingit) and a digital one-sided platform......In this paper we address how the composition of a platform impacts the platform’s business model. By platform’s business model we mean platform features, platform architecture and platform governance. To this end, we construct the Platform Business Model Framework. We apply the framework to three...... in several configurations. The particular platform architecture can explain the difficulties in designing a viable business models for platforms....

  15. Footballers' movement behaviour during 2-, 3-, 4- and 5-a-side small-sided games

    NARCIS (Netherlands)

    Aguiar, Marco; Goncalves, Bruno; Botelho, Goreti; Lemmink, Koen; Sampaio, Jaime

    2015-01-01

    The aim of this study was to compare footballers' movement behaviour during 2-, 3-, 4- and 5-a-side small-sided games. Ten young professional players (age=18.0 +/- 0.67years) participated in 3 bouts of each small-sided games for 6min with 1min of active rest between bouts. Positional data were colle

  16. Decision making in right-sided diverticulitis

    Institute of Scientific and Technical Information of China (English)

    Li-Rung Shyung; Shee-Chan Lin; Shou-Chuan Shih; Chin-Roa Kao; Sun-Yen Chou

    2003-01-01

    AIM: To evaluate systematically our nine-year experience in treating right-sided diverticulitis of the colon, and to explore its clinical and radiological relationship.METHODS: The clinical and radiological data of 40 patients with colonic diverticulitis treated in Mackay Memorial Hospital,Taipei, from 1993 through 2002 were reviewed retrospectively.RESULTS: The average age of the patients with right-sided diverticulitis was 53.1 years, which was 11.6 years younger than that of the patients with left-sided diverticulitis. The preoperative diagnosis of appendicitis was made in 8 of 13 right-sided diverticulitis patients. Nine (69 %) had right lower quadrant abdominal pain for more than 48 hours, and ten patients (77 %) presented with fever. CT findings suggesting acute right-sided diverticulitis including thickening of the intestinal wall and pericolonic inflammation were present in five patients.CONCLUSION: Right-sided diverticulitis is easily confused with acute appendicitis because it occurs at a somewhat younger age than that in left-sided diverticulitis. Barium enema and CT are helpful for the early diagnosis of rightsided diverticulitis. While clearly not required in the majority of patients with right lower quadrant abdominal pain, barium enema and CT may be helpful in making the decision with a clinical history or physical examinations atypical of acute appendicitis.

  17. Effect of knee joint angle on side-to-side strength ratios.

    Science.gov (United States)

    Krishnan, Chandramouli; Williams, Glenn N

    2014-10-01

    Isometric knee extensor and flexor strength are typically tested at different joint angles due to the differences in length-tension relationships of the quadriceps and hamstring muscles. The efficiency of strength testing can be improved if the same angle can be used to test both the knee extensor and flexor muscle groups. The aim of this study was to determine an optimal angle for isometric knee strength testing by examining the effect of knee angle on side-to-side peak torque ratios. Eighteen active young people (9 males and 9 females) participated in this study. Knee extensor and knee flexor strength were tested on both sides at 30°, 60°, and 90° of knee flexion. The effect of knee flexion angle on side-to-side peak torque ratios, raw torque values, and side-to-side flexor-to-extensor torque ratios were assessed. Side-to-side knee extensor peak torque ratios and knee flexor-to-extensor torque ratios differed significantly by knee flexion angle (p = 0.024 and p = 0.011, respectively), but side-to-side knee flexor peak torque ratios did not differ significantly (p = 0.311). When considering both side-to-side peak torque ratios and flexor-to-extensor torque ratios, the values were more symmetrical (i.e., closer to 100%) only at 60° of knee flexion. Our results indicate that both the knee flexors and the knee extensors can be tested clinically at 60° of knee flexion. Our results also indicate that the hamstrings can be tested at any of the 3 angles if the examiner is interested in side-to-side ratios rather than raw torque values. These results may facilitate more efficient and flexible clinical knee strength testing.

  18. Neglected Side Effects After Radical Prostatectomy

    DEFF Research Database (Denmark)

    Frey, Anders Ullmann; Sønksen, Jens; Fode, Mikkel

    2014-01-01

    INTRODUCTION: A series of previously neglected sexually related side effects to radical prostatectomy (RP) has been identified over the recent years. These include orgasm-associated incontinence (OAI), urinary incontinence in relation to sexual stimulation (UISS), altered perception of orgasm......, and the online Cochrane library. The PRISMA guidelines for systematic reviews were followed, and protocol as well as search strategies was registered at http://www.crd.york.ac.uk/Prospero/ (RN: CRD42012003165). MAIN OUTCOME MEASURE: The main outcome measure was incidence rates for the relevant side effects...... been shown to double the risk of OAP. PS occurs in 15-68% of RP patients. Nerve sparing and preservation of erectile function may help preserve penile length. With regard to all side effects, studies indicate that they are reduced over time. CONCLUSIONS: The sexually related side effects summarized...

  19. Side- ja turvanguamet / Indrek Süld

    Index Scriptorium Estoniae

    Süld, Indrek

    2004-01-01

    Ilmunud ka: 2003 : annual report : [Eesti Raudtee]. - Tallinn, 2004, lk. 34-35; 2003 : godovoi ottshjot : [Eesti Raudtee]. - Tallinn, 2004, lk. 34-35. Ülevaade AS-i Eesti Raudtee side- ja turvanguameti tegevusest 2003. aastal. Skeem

  20. Lymphedema as a Cancer Treatment Side Effect

    Science.gov (United States)

    ... Navigating Cancer Care > Side Effects > Lymphedema Request Permissions Lymphedema Approved by the Cancer.Net Editorial Board , 05/ ... years after cancer treatment has ended. Symptoms of lymphedema People with lymphedema in their arm or leg ...

  1. Possible Side-Effects from Vaccines

    Science.gov (United States)

    ... her at risk of contracting a potentially deadly disease. Adenovirus vaccine side-effects What are the risks from Adenovirus vaccine? A vaccine, like any medicine, could cause a serious reaction. But the risk ...

  2. Side Stream Filtration for Cooling Towers

    Energy Technology Data Exchange (ETDEWEB)

    None

    2012-10-20

    This technology evaluation assesses side stream filtration options for cooling towers, with an objective to assess key attributes that optimize energy and water savings along with providing information on specific technology and implementation options. This information can be used to assist Federal sites to determine which options may be most appropriate for their applications. This evaluation provides an overview of the characterization of side stream filtration technology, describes typical applications, and details specific types of filtration technology.

  3. Hematological Side Effects of Atypical Antipsychotic Drugs

    Directory of Open Access Journals (Sweden)

    Serap Erdogan

    2009-10-01

    Full Text Available Atypical antipsychotics cause less frequently extrapyramidal system symptoms, neuroleptic malignant syndrome and hyperprolactinemia than typical antipsychotics. However hematological side effects such as leukopenia and neutropenia could occur during treatment with atypical antipsychotics. These side effects could lead to life threatening situations and the mortality rate due to drug related agranulocytosis is about 5-10%. There are several hypothesis describing the mechanisms underlying drug induced leukopenia and/or neutropenia such as direct toxic effects of these drugs upon the bone marrow or myeloid precursors, immunologic destruction of the granulocytes or supression of the granulopoiesis. Clozapine is the antipsychotic agent which has been most commonly associated with agranulocytosis. A nitrenium ion which is formed by the bioactivation of clozapine is thought to have an important role in the pathophysiogy of this adverse effect. Aside from clozapine, there are several case reports reporting an association between olanzapine, quetiapine, risperidone, ziprasidone, aripiprazole and leukopenia. We did not find any study or case report presenting amisulpride or sulpride related hematological side effects in our literature search. Patients who had hematological side effects during their previous antipsychotic drug treatments and who had lower baseline blood leukocyte counts, have higher risk to develop leukopenia or neutropenia during their current antipsychotic treatment. Once leukopenia and neutropenia develops, drugs thought to be responsible for this side effect should be discontinued or dosages should be lowered. In some cases iniatition of lithium or G-CSF (granulocyte colony-stimulating factor therapy may be helpful in normalizing blood cell counts. Clinicans should avoid any combination of drugs known to cause hematological side effects. Besides during antipsychotic treatment, infection symptoms such as fever, cough, sore throat or

  4. Temporomandibular disorders: the habitual chewing side syndrome.

    Directory of Open Access Journals (Sweden)

    Urbano Santana-Mora

    Full Text Available BACKGROUND: Temporomandibular disorders are the most common cause of chronic orofacial pain, but, except where they occur subsequent to trauma, their cause remains unknown. This cross-sectional study assessed chewing function (habitual chewing side and the differences of the chewing side and condylar path and lateral anterior guidance angles in participants with chronic unilateral temporomandibular disorder. This is the preliminary report of a randomized trial that aimed to test the effect of a new occlusal adjustment therapy. METHODS: The masticatory function of 21 randomly selected completely dentate participants with chronic temporomandibular disorders (all but one with unilateral symptoms was assessed by observing them eat almonds, inspecting the lateral horizontal movement of the jaw, with kinesiography, and by means of interview. The condylar path in the sagittal plane and the lateral anterior guidance angles with respect to the Frankfort horizontal plane in the frontal plane were measured on both sides in each individual. RESULTS: Sixteen of 20 participants with unilateral symptoms chewed on the affected side; the concordance (Fisher's exact test, P = .003 and the concordance-symmetry level (Kappa coefficient κ = 0.689; 95% confidence interval [CI], 0.38 to 0.99; P = .002 were significant. The mean condylar path angle was steeper (53.47(10.88 degrees versus 46.16(7.25 degrees; P = .001, and the mean lateral anterior guidance angle was flatter (41.63(13.35 degrees versus 48.32(9.53 degrees P = .036 on the symptomatic side. DISCUSSION: The results of this study support the use of a new term based on etiology, "habitual chewing side syndrome", instead of the nonspecific symptom-based "temporomandibular joint disorders"; this denomination is characterized in adults by a steeper condylar path, flatter lateral anterior guidance, and habitual chewing on the symptomatic side.

  5. Experimental study on the near wake behind two side-by-side cylinders of unequal diameters

    Science.gov (United States)

    Gao, Yangyang; Yu, Dingyong; Tan, Soonkeat; Wang, Xikun; Hao, Zhiyong

    2010-10-01

    The wake structure behind two side-by-side circular cylinders with unequal diameter was investigated using the particle image velocimetry (PIV) technique. This investigation focused on the asymmetrical flow within the subcritical Reynolds number regime. A comparison between the time-averaged mean flow field of one cylinder and that of two side-by-side cylinders of unequal diameter was made for elucidating the mean flow characteristics attributable to the latter. The distribution of mean velocity behind two side-by-side unequal cylinders was distinctly different from that behind one cylinder, and an asymmetric combination was observed behind the two cylinders. The present paper also presents the authors' interpretation of the generation mechanism of gap flow deflection based on the instantaneous vorticity contours and velocity distribution. The effect of Reynolds number on flow structure was studied by analyzing the mean velocity distribution and time-averaged wake structures. The results showed that vortex formation length decreases with Reynolds number.

  6. Communication technologies for demand side management

    Energy Technology Data Exchange (ETDEWEB)

    Uuspaeae, P. [VTT Energy, Espoo (Finland)

    1998-08-01

    The scope of this research is data communications for electric utilities, specifically for the purposes of Demand Side Management (DSM). Demand Side Management has the objective to change the customer`s end use of energy in a manner that benefits both the customer and the utility. For example, peak demand may be reduced, and the peak demand may be relocated to off peak periods. Thus additional investments in generation and network may be avoided. A number of Demand Side Management functions can be implemented if a communication system is available between the Electric Utility and the Customer. The total communication capacity that is needed, will depend on several factors, such as the functions that are chosen for DSM, and on the number and type of customers. Some functions may be handled with one-way communications, while some other functions need to have two-way communication

  7. DarkSide search for dark matter

    Energy Technology Data Exchange (ETDEWEB)

    Alexander, T.; Alton, D.; Arisaka, K.; Back, H. O.; Beltrame, P.; Benziger, J.; Bonfini, G.; Brigatti, A.; Brodsky, J.; Bussino, S.; Cadonati, L.; Calaprice, F.; Candela, A.; Cao, H.; Cavalcante, P.; Chepurnov, A.; Chidzik, S.; Cocco, A. G.; Condon, C.; D' Angelo, D.; Davini, S.; Vincenzi, M. De; Haas, E. De; Derbin, A.; Pietro, G. Di; Dratchnev, I.; Durben, D.; Empl, A.; Etenko, A.; Fan, A.; Fiorillo, G.; Franco, D.; Fomenko, K.; Forster, G.; Gabriele, F.; Galbiati, C.; Gazzana, S.; Ghiano, C.; Goretti, A.; Grandi, L.; Gromov, M.; Guan, M.; Guo, C.; Guray, G.; Hungerford, E. V.; Ianni, Al; Ianni, An; Joliet, C.; Kayunov, A.; Keeter, K.; Kendziora, C.; Kidner, S.; Klemmer, R.; Kobychev, V.; Koh, G.; Komor, M.; Korablev, D.; Korga, G.; Li, P.; Loer, B.; Lombardi, P.; Love, C.; Ludhova, L.; Luitz, S.; Lukyanchenko, L.; Lund, A.; Lung, K.; Ma, Y.; Machulin, I.; Mari, S.; Maricic, J.; Martoff, C. J.; Meregaglia, A.; Meroni, E.; Meyers, P.; Mohayai, T.; Montanari, D.; Montuschi, M.; Monzani, M. E.; Mosteiro, P.; Mount, B.; Muratova, V.; Nelson, A.; Nemtzow, A.; Nurakhov, N.; Orsini, M.; Ortica, F.; Pallavicini, M.; Pantic, E.; Parmeggiano, S.; Parsells, R.; Pelliccia, N.; Perasso, L.; Perasso, S.; Perfetto, F.; Pinsky, L.; Pocar, A.; Pordes, S.; Randle, K.; Ranucci, G.; Razeto, A.; Romani, A.; Rossi, B.; Rossi, N.; Rountree, S. D.; Saggese, P.; Saldanha, R.; Salvo, C.; Sands, W.; Seigar, M.; Semenov, D.; Shields, E.; Skorokhvatov, M.; Smirnov, O.; Sotnikov, A.; Sukhotin, S.; Suvarov, Y.; Tartaglia, R.; Tatarowicz, J.; Testera, G.; Thompson, J.; Tonazzo, A.; Unzhakov, E.; Vogelaar, R. B.; Wang, H.; Westerdale, S.; Wojcik, M.; Wright, A.; Xu, J.; Yang, C.; Zavatarelli, S.; Zehfus, M.; Zhong, W.; Zuzel, G.

    2013-11-22

    The DarkSide staged program utilizes a two-phase time projection chamber (TPC) with liquid argon as the target material for the scattering of dark matter particles. Efficient background reduction is achieved using low radioactivity underground argon as well as several experimental handles such as pulse shape, ratio of ionization over scintillation signal, 3D event reconstruction, and active neutron and muon vetos. The DarkSide-10 prototype detector has proven high scintillation light yield, which is a particularly important parameter as it sets the energy threshold for the pulse shape discrimination technique. The DarkSide-50 detector system, currently in commissioning phase at the Gran Sasso Underground Laboratory, will reach a sensitivity to dark matter spin-independent scattering cross section of 10-45 cm2 within 3 years of operation.

  8. Areeda-turner in two-sided markets

    NARCIS (Netherlands)

    Behringer, S.; Filistrucchi, L.

    2015-01-01

    We extend the Areeda–Turner rule to two-sided markets. We show that a two-sided monopolist may find it short-run profit-maximizing to charge a price below marginal cost on one side of the market. Hence showing that the price is below marginal cost on one side of a two-sided market cannot be consider

  9. Left-sided omental torsion: CT appearance

    Energy Technology Data Exchange (ETDEWEB)

    Aoun, N.; Haddad-Zebouni, S.; Slaba, S.; Ghossain, M. [Hotel-Dieu de France Hospital, Beirut (Lebanon). Dept. of Radiology; Noun, R. [Hotel-Dieu de France Hospital, Beirut (Lebanon). Dept. of General Surgery

    2001-01-01

    A 34-year-old male presented with exquisite left flank pain. Computed tomography showed a hyperdense vascular structure surrounded by whirling linear streaks situated in the greater omentum under the splenic flexure of the colon. Omental stranding extended caudally into the pelvis where part of the inflamed omentum entered a left inguinal hernia sac. Surgery revealed left-sided torsion of the greater omentum. Left-sided omental torsion is infrequent and pre-operative diagnosis is rarely established. The CT findings of an omental fatty mass with a whirling pattern is characteristic of omental torsion. Preoperative diagnosis is important because conservative management has been suggested. (orig.)

  10. Update on side effects from common vaccines.

    Science.gov (United States)

    Song, Benjamin J; Katial, Rohit K

    2004-11-01

    Vaccines have had a tremendous impact on public health by reducing morbidity and mortality from a variety of virulent pathogens. However, unintended side effects continue to pose a potential risk that may outweigh the vaccine's protective attributes. In this review, we discuss recent articles and controversies pertaining to vaccine-associated adverse events. Included in the discussion are influenza, hepatitis B, measles-mumps-rubella, diphtheria-tetanus-pertussis, polio, Haemophilus influenzae type b, and rotavirus vaccines. The importance and contribution of vaccine constituents (such as thimerosal) to side effects is also reviewed.

  11. Illinois Early Childhood Program Standards Matrix. (A Side-by-Side Comparison).

    Science.gov (United States)

    Illinois State Dept. of Human Services, East St. Louis. Head Start State Collaboration Office.

    This document contains a matrix offering a side-by-side comparison of almost 40 criteria among 7 sets of early childhood program standards. The standards are: (1) Head Start Program Performance Standards; (2) Illinois Department of Children and Family Services Child Care Licensing Standards; (3) Illinois Department of Human Services (IDHS) Center…

  12. Computer-mediated communication as a channel for social resistance : The strategic side of SIDE

    NARCIS (Netherlands)

    Spears, R; Lea, M; Corneliussen, RA; Postmes, T; Ter Haar, W

    2002-01-01

    In two studies, the authors tested predictions derived from the social identity model of deindividuation effects (SIDE) concerning the potential of computer-mediated communication (CMC) to serve as a means to resist powerful out-groups. Earlier research using the SIDE model indicates that the anonym

  13. Water Quality Performance of Three Side-by-Side Permeable Pavement Surface Materials: Three Year Update

    Science.gov (United States)

    Communities are increasingly installing structural low impact development (LID) practices to mange stormwater and reduce pollutant loads associated with stormwater runoff. Permeable pavement is a LID practice that has limited research on working-scale, side-by-side performance o...

  14. Photon side-bands in mesoscopics

    DEFF Research Database (Denmark)

    Jauho, Antti-Pekka

    1998-01-01

    This paper reviews several applications of photonic side bands, used by Buttiker and Landauer (Phys. Rev. Lett. 49, 1739 (1982)) in their theory of traversal time in tunneling, in transport and optics of mesoscopic systems. Topics include generalizations of the transmission theory of transport...

  15. Compressive video sensing with side information.

    Science.gov (United States)

    Yuan, Xin; Sun, Yangyang; Pang, Shuo

    2017-04-01

    Our temporally compressive imaging system reconstructs a high-speed image sequence from a single, coded snapshot. The reconstruction quality, similar to that of other compressive sensing systems, often depends on the structure of the measurement, as well as the choice of regularization. In this paper, we report a compressive video system that also captures the side information to aid in the reconstruction of high-speed scenes. The integration of the side information not only improves the quality of reconstruction, but also reduces the dependence of the reconstruction on regularization. We have implemented a system prototype that splits the field of view of a single camera into two channels: one channel captures the coded, low-frame-rate measurement for high-speed video reconstruction, and the other channel captures a direct measurement without coding as the side information. A joint reconstruction model is developed to recover the high-speed videos from the two channels. By analyzing both the experimental and the simulation results, the reconstructions with side information have demonstrated superior performances in terms of both the peak signal-to-noise ratio and structural similarity.

  16. Protection of the side of the head.

    Science.gov (United States)

    Gilchrist, A; Mills, N J

    1996-07-01

    The side of the head is a frequent impact site for pedal cyclists, motorcyclists, and industrial workers. It is vulnerable to impact, yet many helmet standards do not have impact tests at the side of the helmet. Laboratory impact tests should reproduce the phenomena in real impacts, but usually they do not allow the headform to rotate, or ignore the effect of the neck on the motion of the head. The authors designed a linkage, simulating the flexibility of the neck, for use with anthropomorphic dummies in helmet testing. Impacts at the side of the helmet, normal to the helmet surface, were made with flat and hemispherical strikers. Head rotation during impacts caused the impact site to move, in some cases to below the level protected by the helmet. The peak angular head acceleration correlated with the peak linear accelerations. Neck flexibility means that helmets can protect the head from higher kinetic energy impacts than those specified in standards using immovable headforms or impact anvils. The load spreading efficiency of polypropylene foam, used in soft shell bicycle helmets, is better than that of polystyrene foam. The authors conclude that the side of the head can be protected by a suitable helmet design.

  17. Solar cell with back side contacts

    Energy Technology Data Exchange (ETDEWEB)

    Nielson, Gregory N; Okandan, Murat; Cruz-Campa, Jose Luis; Resnick, Paul J; Wanlass, Mark Woodbury; Clews, Peggy J

    2013-12-24

    A III-V solar cell is described herein that includes all back side contacts. Additionally, the positive and negative electrical contacts contact compoud semiconductor layers of the solar cell other than the absorbing layer of the solar cell. That is, the positive and negative electrical contacts contact passivating layers of the solar cell.

  18. On one-sided torsion pair

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    Motivated by the concept of a torsion pair in a pre-triangulated category induced by Beligiannis and Reiten, the notion of a left (right) torsion pair in the left (right) triangulated category is introduced and investigated. We provide new connections between different aspects of torsion pairs in one-sided triangulated categories, pre-triangulated categories, stable categories and derived categories.

  19. The Dark Side of Bank Wholesale Funding

    NARCIS (Netherlands)

    Huang, R.; Ratnovksi, L.

    2009-01-01

    Commercial banks increasingly use short-term wholesale funds to supplement traditional retail deposits. Existing literature mainly points to the "bright side" of wholesale funding: sophisticated financiers can monitor banks, disciplining bad ones but refinancing solvent ones. This paper models a "da

  20. Demand Side Management for Multiple Devices

    NARCIS (Netherlands)

    Molderink, Albert; Bakker, Vincent; Smit, Gerard J.M.

    2013-01-01

    Steering a heterogeneous set of devices in a Smart Grid using cost functions: Demand Side Management (DSM) is an important element in smart grids. DSM is already in operation for large consumers, but thorough research is required into DSM on a building level within the distribution grid.

  1. The Social Side Effects of Acetaminophen

    Science.gov (United States)

    Mischkowski, Dominik

    About 23% of all adults in the US take acetaminophen during an average week (Kaufman, Kelly, Rosenberg, Anderson, & Mitchell, 2002) because acetaminophen is an effective physical painkiller and easily accessible over the counter. The physiological side effects of acetaminophen are well documented and generally mild when acetaminophen is consumed in the appropriate dosage. In contrast, the psychological and social side effects of acetaminophen are largely unknown. Recent functional neuroimaging research suggests that the experience of physical pain is fundamentally related to the experience of empathy for the pain of other people, indicating that pharmacologically reducing responsiveness to physical pain also reduces cognitive, affective, and behavioral responsiveness to the pain of others. I tested this hypothesis across three double-blind between-subjects drug intervention studies. Two experiments showed that acetaminophen had moderate effects on empathic affect, specifically personal distress and empathic concern, and a small effect on empathic cognition, specifically perceived pain, when facing physical and social pain of others. The same two experiments and a third experiment also showed that acetaminophen can increase the willingness to inflict pain on other people, i.e., actual aggressive behavior. This effect was especially pronounced among people low in dispositional empathic concern. Together, these findings suggest that the physical pain system is more involved in the regulation of social cognition, affect, and behavior than previously assumed and that the experience of physical pain and responsiveness to the pain of others share a common neurochemical basis. Furthermore, these findings suggest that acetaminophen has unappreciated but serious social side effects, and that these side effects may depend on psychological characteristics of the drug consumer. This idea is consistent with recent theory and research on the context-dependency of neurochemical

  2. Medicated Janus fibers fabricated using a Teflon-coated side-by-side spinneret.

    Science.gov (United States)

    Yu, Deng-Guang; Yang, Chen; Jin, Miao; Williams, Gareth R; Zou, Hua; Wang, Xia; Bligh, S W Annie

    2016-02-01

    A family of medicated Janus fibers that provides highly tunable biphasic drug release was fabricated using a side-by-side electrospinning process employing a Teflon-coated parallel spinneret. The coated spinneret facilitated the formation of a Janus Taylor cone and in turn high quality integrated Janus structures, which could not be reliably obtained without the Teflon coating. The fibers prepared had one side consisting of polyvinylpyrrolidone (PVP) K60 and ketoprofen, and the other of ethyl cellulose (EC) and ketoprofen. To modulate and tune drug release, PVP K10 was doped into the EC side in some cases. The fibers were linear and had flat morphologies with an indent in the center. They provide biphasic drug release, with the PVP K60 side dissolving very rapidly to deliver a loading dose of the active ingredient, and the EC side resulting in sustained release of the remaining ketoprofen. The addition of PVP K10 to the EC side was able to accelerate the second stage of release; variation in the dopant amount permitted the release rate and extent this phase to be precisely tuned. These results offer the potential to rationally design systems with highly controllable drug release profiles, which can complement natural biological rhythms and deliver maximum therapeutic effects.

  3. Server-side Statistics Scripting in PHP

    Directory of Open Access Journals (Sweden)

    Jan de Leeuw

    1997-06-01

    Full Text Available On the UCLA Statistics WWW server there are a large number of demos and calculators that can be used in statistics teaching and research. Some of these demos require substantial amounts of computation, others mainly use graphics. These calculators and demos are implemented in various different ways, reflecting developments in WWW based computing. As usual, one of the main choices is between doing the work on the client-side (i.e. in the browser or on the server-side (i.e. on our WWW server. Obviously, client-side computation puts fewer demands on the server. On the other hand, it requires that the client downloads Java applets, or installs plugins and/or helpers. If JavaScript is used, client-side computations will generally be slow. We also have to assume that the client is installed properly, and has the required capabilities. Requiring too much on the client-side has caused browsing machines such as Netscape Communicator to grow beyond all reasonable bounds, both in size and RAM requirements. Moreover requiring Java and JavaScript rules out such excellent browsers as Lynx or Emacs W3. For server-side computing, we can configure the server and its resources ourselves, and we need not worry about browser capabilities and configuration. Nothing needs to be downloaded, except the usual HTML pages and graphics. In the same way as on the client side, there is a scripting solution, where code is interpreted, or a ob ject-code solution using compiled code. For the server-side scripting, we use embedded languages, such as PHP/FI. The scripts in the HTML pages are interpreted by a CGI program, and the output of the CGI program is send to the clients. Of course the CGI program is compiled, but the statistics procedures will usually be interpreted, because PHP/FI does not have the appropriate functions in its scripting language. This will tend to be slow, because embedded languages do not deal efficiently with loops and similar constructs. Thus a first

  4. Scrutable Mobile Client-side Personalization

    Directory of Open Access Journals (Sweden)

    Muhammad Asif

    2015-04-01

    Full Text Available Personalization has become an essential feature of mobile services of different domains. On the other hand, users have conflicting needs of personalized experience and privacy. This leads to the question of how to maximize the user’s experience of personalized mobile services while keeping privacy. One possible solution is to provide user’s control of their personal data by keeping their user model on their personal mobile devices. In this way, a user can scrutinize the data while sharing with service providers depending on her/his requirements. The client-side personalization approach can shift the control of privacy to the users and can involve them in personalization process. Transparency and user control can increase the user’s trust. In this paper, we have proposed a solution with the objective of scrutable client-side personalization while keeping the user in control of both privacy and personalization process.

  5. Side Chain Cyclized Aromatic Amino Acids

    DEFF Research Database (Denmark)

    Van der Poorten, Olivier; Knuhtsen, Astrid; Sejer Pedersen, Daniel

    2016-01-01

    Constraining the conformation of flexible peptides is a proven strategy to increase potency, selectivity, and metabolic stability. The focus has mostly been on constraining the backbone dihedral angles; however, the correct orientation of the amino acid side chains (χ-space) that constitute...... the peptide pharmacophore is equally important. Control of χ-space utilizes conformationally constrained amino acids that favor, disfavor, or exclude the gauche (-), the gauche (+), or the trans conformation. In this review we focus on cyclic aromatic amino acids in which the side chain is connected...... to the peptide backbone to provide control of χ(1)- and χ(2)-space. The manifold applications for cyclized analogues of the aromatic amino acids Phe, Tyr, Trp, and His within peptide medicinal chemistry are showcased herein with examples of enzyme inhibitors and ligands for G protein-coupled receptors....

  6. Methylphenidate Abuse and Psychiatric Side Effects

    OpenAIRE

    Morton, W. Alexander; Stockton, Gwendolyn G.

    2000-01-01

    Methylphenidate is a central nervous system stimulant drug that has become the primary drug of choice in treating attention-deficit/hyperactivity disorder in children. Side effects are usually mild and are generally well tolerated by patients. Along with increases in prescribing frequency, the potential for abuse has increased. Intranasal abuse produces effects rapidly that are similar to the effects of cocaine in both onset and type. The clinical picture of stimulant abuse produces a wide ar...

  7. Integrated double-sided silicon microstrip detectors

    Directory of Open Access Journals (Sweden)

    Perevertailo V. L.

    2011-11-01

    Full Text Available The problems of design, technology and manufacturing double-sided silicon microstrip detectors using standard equipment production line in mass production of silicon integrated circuits are considered. The design of prototype high-energy particles detector for experiment ALICE (CERN is presented. The parameters of fabricated detectors are comparable with those of similar foreign detectors, but they are distinguished by lesser cost.

  8. Demand side management of electric car charging

    DEFF Research Database (Denmark)

    Finn, P.; Fitzpatrick, C.; Connolly, David

    2012-01-01

    in terms of distributed energy storage and flexible load. This paper examines how optimising the charging cycles of an electriccar using DSM (DemandSideManagement) based on a number of criteria could be used to achieve financial savings, increased demand on renewable energy, reduce demand on thermal...... generation plant, and reduce peak load demand. The results demonstrate that significant gains can be achieved using currently available market data which highlights the point that DSM can be implemented without any further technological advents....

  9. Client-side Skype forensics: an overview

    Science.gov (United States)

    Meißner, Tina; Kröger, Knut; Creutzburg, Reiner

    2013-03-01

    IT security and computer forensics are important components in the information technology. In the present study, a client-side Skype forensics is performed. It is designed to explain which kind of user data are stored on a computer and which tools allow the extraction of those data for a forensic investigation. There are described both methods - a manual analysis and an analysis with (mainly) open source tools, respectively.

  10. The Dark Side of the Moon

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    A combo photo released by the China National Space Administration(CNSA)on December 11 shows a crater on the dark side of the moon.This image was reportedly taken by Chang’e-1, the country’s first lunar probe,on December 4. On December 12,a grand ceremony was held in Beijing to celebrate the success of the first stage of China’s lunar probe program.President Hu Jintao announced on the occasion that the

  11. Opiates and elderly: Use and side effects

    Directory of Open Access Journals (Sweden)

    Diane L Chau

    2008-06-01

    Full Text Available Diane L Chau1, Vanessa Walker2, Latha Pai3, Lwin M Cho4University of Nevada School of Medicine, Reno, NV, USA 1Division Geriatric Medicine, 2Internal Medicine, 3Psychiatry, 4Geriatric Medicine, Sierra Nevada Healthcare System, Veterans Affairs Medical Center, Reno, NV, USAAbstract: The evaluation of pain and the subsequent issue of pain control is a clinical challenge that all healthcare providers face. Pain in the elderly population is especially difficult given the myriad of physiological, pharmacological, and psychological aspects of caring for the geriatric patient. Opiates are the mainstay of pain treatment throughout all age groups but special attention must be paid to the efficacy and side effects of these powerful drugs when prescribing to a population with impaired metabolism, excretion and physical reserve. In a random chart review of 300 US veterans, 44% of those receiving an analgesic also received opioids. The increasing use of opiates for pain management by healthcare practitioners requires that those prescribing opioids be aware of the special considerations for treating the elderly. This article will address the precautions one must take when using opiates in the geriatric population, as well as the side effects and ways to minimize them.Keywords: opiates, pain, elderly, side effects

  12. Side abutment pressure distribution by field measurement

    Institute of Scientific and Technical Information of China (English)

    WANG Lian-guo; SONG Yang; HE Xing-hua; ZHANG Jian

    2008-01-01

    Given the 7123 working face in the Qidong Coal Mine of the Wanbei Mining Group, nine dynamic roof monitors were installed in the crossheading to measure the amount and velocity of roof convergence in different positions and at different times and three steel bored stress sensors were installed in the return airway to measure rock stress at depth. On the basis of this arrangement, the rule of change of the distribution of the side abutment pressure with the advance of the working face and movement of overlying strata was studied. The rule of change and the stability of rock stress at depth were measured. Secondly, the affected area and stability time of the side abutment pressure were also studied. The results show that: 1) During working, the face advanced distance was from 157 m to 99 m, the process was not effected by mining induced pressure. When the distance was 82 m, the position of peak stress was 5 m away from the coal wall. When the distance was 37 m, the position of peak stress away from the coal wall was about 15 m to 20 m and finally reached a steady state; 2) the time and the range of the peak of side rock pressure obtained from stress sensors were consistent with the results from the dynamic roof monitors; 3) the position of the peak pressure was 25 m away from the coal wall.

  13. Safety Assessment for a Side-by-side Offloading Mooring System

    Institute of Scientific and Technical Information of China (English)

    Liping Sun; Qiang He; Shangmao Ai

    2011-01-01

    In order to improve the safety properties of an offloading system with side-by-side (SBS) mooring in which the FPSO is moored by a yoke system in the field of BZ25-1,it is necessary to analyze those properties.According to the experience of similar projects,tow strategies of different offloading arrangements were discussed by using the 3-D radiation/diffraction theory and quasi-static time domain method to assess their respective safety properties.Through the safety assessment analysis of different arrangement comparisons,various ways to improve the safety properties of offloading systems with side-by-side mooring were verified by analyzing the tension in the mooring lines and the fender deflection.Through comparison it can be concluded that by enlarging the key factors properly,including the size of the fenders and the hawsers as well as the number of hawsers,a better satiety performance can be achieved.

  14. Functionally Graded Ceramics Fabricated with Side-by-Side Tape Casting for Use in Magnetic Refrigeration

    DEFF Research Database (Denmark)

    Bulatova, Regina; Bahl, Christian; Andersen, Kjeld Bøhm;

    2015-01-01

    variations of solvent and binder system concentrations have a substantial effect on slurry viscosity. Varying these parameters showed that side-by-side tape casting with a well-defined interface area is possible for slurries with viscosities above 3500 mPa s at a casting shear rate of 3.3 s -1......Functionally graded ceramic tapes have been fabricated by a side-by-side tape casting technique. This study shows the possibility and describes the main principles of adjacent coflow of slurries resulting in formation of thin plates of graded ceramic material. Results showed that the small...... of developing this graded ceramic tape casting was applications of these specific magnetocaloric properties within the magnetic refrigeration technology....

  15. Left-Sided Patent Ductus Arteriosus in a Right-Sided Aortic Arch

    Directory of Open Access Journals (Sweden)

    Ming-Yen Ng

    2014-01-01

    Full Text Available We present a 31-year-old female with repaired tetralogy of Fallot (TOF and right-sided aortic arch (RAA with left-sided patent ductus arteriosus (PDA originating from the left brachiocephalic artery. This is a rare finding but most common site for a PDA in TOF and a RAA. To the best of our knowledge, this is the first demonstration of this rare finding on MRI in the literature.

  16. Aerodynamic drag from two tubes in side-by-side arrangement for different tube shapes

    Directory of Open Access Journals (Sweden)

    Олександр Михайлович Терех

    2016-06-01

    Full Text Available Experimental investigations of aerodynamic drag from two tubes in side-by-side arrangement for different tube shapes in the range of Reynolds numbers from 4000 to16000 are performed. Comparison of experimental data is executed. It is set, that the tubes of drop-shaped form have less aerodynamic drag and the tubes of flat-oval and dumb-bell forms have greater drag as compared to drag of circular tubes

  17. Experimental study on the near wake behind two side-by-side cylinders of unequal diameters

    Energy Technology Data Exchange (ETDEWEB)

    Gao Yangyang; Yu Dingyong [College of Engineering, Ocean University of China, Qingdao 266100 (China); Tan, Soonkeat [School of Civil and Environmental Engineering, Nanyang Technological University, Singapore 639798 (Singapore); Wang Xikun [Maritime Research Center, Nanyang Technological University, Singapore 639798 (Singapore); Hao Zhiyong, E-mail: gaoyangyangouc@163.co [Shanghai Maritime University, Shanghai 200135 (China)

    2010-10-15

    The wake structure behind two side-by-side circular cylinders with unequal diameter was investigated using the particle image velocimetry (PIV) technique. This investigation focused on the asymmetrical flow within the subcritical Reynolds number regime. A comparison between the time-averaged mean flow field of one cylinder and that of two side-by-side cylinders of unequal diameter was made for elucidating the mean flow characteristics attributable to the latter. The distribution of mean velocity behind two side-by-side unequal cylinders was distinctly different from that behind one cylinder, and an asymmetric combination was observed behind the two cylinders. The present paper also presents the authors' interpretation of the generation mechanism of gap flow deflection based on the instantaneous vorticity contours and velocity distribution. The effect of Reynolds number on flow structure was studied by analyzing the mean velocity distribution and time-averaged wake structures. The results showed that vortex formation length decreases with Reynolds number.

  18. Stabilization of Gob-Side Entry with an Artificial Side for Sustaining Mining Work

    Directory of Open Access Journals (Sweden)

    Hong-sheng Wang

    2016-07-01

    Full Text Available A concrete artificial side (AS is introduced to stabilize a gob-side entry (GSE. To evaluate the stability of the AS, a uniaxial compression failure experiment was conducted with large and small-scale specimens. The distribution characteristics of the shear stress were obtained from a numerical simulation. Based on the failure characteristics and the variation of the shear stress, a failure criterion was determined and implemented in the strengthening method for the artificial side. In an experimental test, the distribution pattern of the maximum shear stress showed an X shape, which contributed to the failure shape of the specimen. The shear stress distribution and failure shape are induced by a combination of two sets of shear stresses, which implies that failure of the AS follows the twin shear strength theory. The use of anchor bolts, bolts, and anchor bars enhances the shear strength of the artificial side. When this side is stable, the components can constrain the lateral deformation as well as improve the internal friction angle and cohesion. When the AS is damaged, the components prevent the sliding of broken blocks along the shear failure plane and improve the residual strength of the artificial side. When reinforced with an anchor bar, the AS is still stable even after mining operations for three years.

  19. Angle Specific Analysis of Side-to-Side Asymmetry in the Shoulder Rotators

    Directory of Open Access Journals (Sweden)

    Cassio V. Ruas

    2015-08-01

    Full Text Available Although side-to-side asymmetry of the shoulder rotators calculated by independent peak torque (IPT has been used for interpretation of injury risks in athletes, it may not measure strength through the entire range of motion (ROM tested. The aim of this study was to compare side-to-side asymmetry of the shoulder rotators between independent peak torque (IPT and ten-degree angle specific torque (AST. Twenty healthy adult males (24.65 ± 2.4 years performed concentric and eccentric internal rotation (IR and external rotation (ER of the preferred and non-preferred arms on an isokinetic dynamometer at 60°/s through 150° of total ROM. The total ROM was divided into 14 ten-degree angles of the physiological ROM from −90° of ER to 60° of IR. Concentric and eccentric IR IPT (10.5% ± 8.7% and 12.1% ± 7.2% and ER IPT (13.6% ± 9.8% and 8.7% ± 5.6% were significantly less than AST at several angles (p < 0.05. IPT might lead to erroneous interpretations of side-to-side asymmetry in the shoulder rotators and does not represent the entire ROM tested. This information could be used to prescribe strength exercises to enhance overhead performance and reduce risk of shoulder injuries.

  20. [Side effects of third generation progestins].

    Science.gov (United States)

    Sitruk-Ware, R

    1993-04-01

    A large number of publications on oral contraceptives (OC) can be found in the medical literature. These reports deal not only with mode of action or efficacy of OCs but also with side effects. Adverse drug reactions (ADR) are not accepted nor acceptable from a population of young women free of disease who expect from their mode of contraception to be fully efficient and devoid from side effects. In most instances, side effects observed with OCs as well as their efficacy are related to the total dose of steroïds contained in the combination, to the balance between the estrogen and the progestin content and to the specific characteristics of the molecules. Cardiovascular morbidity and mortality reported in OC users have been related firstly to the ethinylestradiol (EE) and as a first step, the estrogen dose has been reduced in the OCs synthesized in the 70s. Later on, cardiovascular risk has been correlated to lipid profile changes and progestins with androgenic properties have been made responsible for cardiovascular events reported in OC users. In order to minimize the incidence of ADRs and to induce beneficial changes in lipid patterns, new progestational molecules devoid of androgenic properties have been recently synthesized. Three compounds called "third generation" progestins, derived from levonorgestrel are presently available in Europe. These three gonane progestins demonstrate affinity for the androgenic receptor, but when administered together with EE do not oppose the estrogenic effect observed on protein markers such as the Sex Hormone Binding Globulin (SHBG) or the High Density Lipoprotein (HDL).(ABSTRACT TRUNCATED AT 250 WORDS)

  1. The dark side of food addiction.

    Science.gov (United States)

    Parylak, Sarah L; Koob, George F; Zorrilla, Eric P

    2011-07-25

    In drug addiction, the transition from casual drug use to dependence has been linked to a shift away from positive reinforcement and toward negative reinforcement. That is, drugs ultimately are relied on to prevent or relieve negative states that otherwise result from abstinence (e.g., withdrawal) or from adverse environmental circumstances (e.g., stress). Recent work has suggested that this "dark side" shift also is a key in the development of food addiction. Initially, palatable food consumption has both positively reinforcing, pleasurable effects and negatively reinforcing, "comforting" effects that can acutely normalize organism responses to stress. Repeated, intermittent intake of palatable food may instead amplify brain stress circuitry and downregulate brain reward pathways such that continued intake becomes obligatory to prevent negative emotional states via negative reinforcement. Stress, anxiety and depressed mood have shown high comorbidity with and the potential to trigger bouts of addiction-like eating behavior in humans. Animal models indicate that repeated, intermittent access to palatable foods can lead to emotional and somatic signs of withdrawal when the food is no longer available, tolerance and dampening of brain reward circuitry, compulsive seeking of palatable food despite potentially aversive consequences, and relapse to palatable food-seeking in response to anxiogenic-like stimuli. The neurocircuitry identified to date in the "dark" side of food addiction qualitatively resembles that associated with drug and alcohol dependence. The present review summarizes Bart Hoebel's groundbreaking conceptual and empirical contributions to understanding the role of the "dark side" in food addiction along with related work of those that have followed him.

  2. Cardiologic side effects of psychotropic drugs

    Institute of Scientific and Technical Information of China (English)

    Giuseppe Marano; Gianandrea Traversi; Enrico Romagnoli; Valeria Catalano; Marzia Lotrionte; Antonio Abbate; Giuseppe Biondi-Zoccai; Marianna Mazza

    2011-01-01

    Psychotropic drugs can produce cardiovascular side effects associated with a degree of cardiotoxicity.The coexistence of a heart disease complicates the management of mental illness,can contribute to a reduced quality of life and a worse illness course.The co-occurrence of psychiatric disorders in cardiac patients might affect the clinical outcome and morbidity.Moreover,the complex underlying mechanism that links these two conditions remains unclear.This paper discusses the known cardiovascular complications of psychotropic drugs and analyzes the important implications of antidepressive treatment in patients with previous cardiac history.

  3. Right-Sided Sigmoid Diverticular Perforation

    Directory of Open Access Journals (Sweden)

    Andrew Little

    2012-04-01

    Full Text Available Diverticulosis is a common disorder among geriatric patients, of whom 10% to 25% go on to develop diverticulitis. Known complications of diverticulitis include formation of phlegmon, fistula, bowel obstruction, bleeding, perforation, and colonic abscess. A less common complication is perforation with formation of an extra-abdominal necrotizing abscess. This case is a report of an 83-year-old female who presented to the emergency department with a necrotizing abdominal wall abscess secondary to right-sided diverticular microperforation. [West J Emerg Med. 2012;13(1:103–105.

  4. The Other Side of GDP Growth

    Institute of Scientific and Technical Information of China (English)

    Zhan Yong; Cai Fang

    2011-01-01

    @@ THE rise of China's GDP ranking has not only led the world to rediscover China, but also reminded China to examine its own development.Both sides of the issue should be considered. On the one hand, China topping Japan [the world's previous second largest economy] in terms of GDP marks the rising of Chinas economic status, which is a milestone in the modern world economic history since Japan replaced the former Federal Republic of Germany as the world's second largest economy in 1968.

  5. Side effects of external tooth bleaching

    DEFF Research Database (Denmark)

    E.M., Bruzell; Pallesen, Ulla; Thoresen, N.R.

    2013-01-01

    -office = 39.3% [n = 28]; p >0.05; 95% CI [OR]: 0.198‑1.102) whereas prevalence of gingival irritation was higher after in-office treatment (at-home = 14.0%; in-office = 35.7%; p ... attributed to the bleaching treatment in the at-home and in-office groups, respectively. Predictors for side effects were tooth sensitivity, surface loss and gingivitis when observed at inclusion. Treatment-related predictors were bleaching concentration and contact between tray and gingiva. Conclusions...

  6. Illegal immigration: a supply side analysis.

    Science.gov (United States)

    Bandyopadhyay, S; Bandyopadhyay, S C

    1998-12-01

    "This paper analyzes the supply-side determinants of illegal immigration using a three-sector general equilibrium model of the source country. Agricultural liberalization raises illegal immigration while liberalization of the high tech sector reduces it. In contrast, capital mobility in the source country renders trade policy ineffective for controlling illegal immigration. Paradoxically, increased enforcement (by the host country) may raise source country unskilled wages, although illegal immigration falls. Finally, under capital mobility, a rise in the source country restrictions on capital inflow raises the level of illegal immigration and reduces the effectiveness of border enforcement efforts by the host country."

  7. Side chain polysiloxanes with phthalocyanine moieties

    Directory of Open Access Journals (Sweden)

    T. Ganicz

    2012-05-01

    Full Text Available Side chain polysiloxane with 5-(pentyloxy-3-methyloxy-9,10,16,17,23,24-hexakis(octenyloxyphthalocyanine moieties is synthesized by hydrosilylation reaction. The phase behavior and thermooptical properties of the polysiloxane and starting 2-(pent-4-enyloxy-3-methyloxy-9,10,16,17,23,24-hexakis(octenyloxyphthalocyanine is examined by POM (Polarizing optical microscopy, TOA (thermooptical analysis, DSC (differential scanning calorimetry, AFM (atomic force microscopy and SAXS (small angle X-ray scattering studies. The effect of the attachment of phthalocyanine to polysiloxane chains over phase transitions and phase morphology is discussed in details.

  8. THE TWO SIDES OF MONEY LAUNDERING

    Directory of Open Access Journals (Sweden)

    Corina – Maria ENE

    2014-12-01

    Full Text Available The mainly goal of money laundering is to carry out more and more illegal economic transactions or activities to produce individual or groups gains and then to legitimate them. Money laundering converts illicit source of money generated by criminal activities in order to hide the connection between money and their original illegal activities. This is one of money laundering side. The second side implies corruption. While money laundering is a passing channel for illicit funds due to its criminal origin source, such funds may derive from corruption offences. All corruption’s forms represent the most important illicit funds branches for money laundering process. Corrupt people methods used to exploit the national and international financial system reflect the relationship between those two criminal activities. Criminals achieve their personal interests by hiding their corruption proceeds and transfer these gains to official economies. Corruption spread in any society entails money laundering spread, and the converse, too. There is a quite “indecent” relationship between money laundering and corruption. This paper tries to identify the multiple connections between the two phenomenons showing the negative impacts these criminal behaviours are having on the national and international economy. We conclude by highlighting the necessity of a multidisciplinary approach in order to fight against money laundering and corruption by integrating these problem frameworks at national level. International community must focus their resources on money laundering and corruption risks areas and maximize their response impact.

  9. Industrial demand side management status report - synopsis

    Energy Technology Data Exchange (ETDEWEB)

    Hopkins, M.E.F.; Conger, R.L.; Foley, T.J. [and others

    1996-05-01

    Industrial demand side management (DSM) programs, though not as developed or widely implemented as residential and commercial programs, hold the promise of significant energy savings-savings that will benefit industrial firms, utilities and the environment. This paper is a synopsis of a larger research report, Industrial Demand Side Management: A Status Report, prepared for the U.S. Department of Energy. The report provides an overview of and rationale for DSM programs. Benefits and barriers are described, and data from the Manufacturing Energy Consumption Survey are used to estimate potential electricity savings from industrial energy efficiency measures. Overcoming difficulties to effective program implementation is worthwhile, since rough estimates indicate a substantial potential for electricity savings. The report categorizes types of DSM programs, presents several examples of each type, and explores elements of successful programs. Two in-depth case studies (of Boise Cascade and of Eli Lilly and Company) illustrate two types of effective DSM programs. Interviews with staff from state public utility commissions indicate the current thinking about the status and future of industrial DSM programs. Finally, the research report also includes a comprehensive bibliography, a description of technical assistance programs, and an example of a methodology for evaluating potential or actual savings from projects.

  10. Industrial demand side management status report: Synopsis

    Energy Technology Data Exchange (ETDEWEB)

    Hopkins, M.E.F.; Conger, R.L.; Foley, T.J.; Parker, J.W.; Placet, M.; Sandahl, L.J.; Spanner, G.E.; Woodruff, M.G.; Norland, D.

    1995-08-01

    Industrial demand side management (DSM) programs, though not as developed or widely implemented as residential and commercial programs, hold the promise of significant energy savings-savings that will benefit industrial firms, utilities and the environment. This paper is a synopsis of a larger research report, Industrial Demand Side Management. A Status Report, prepared for the US Department of Energy. The report provides an overview of and rationale for DSM programs. Benefits and barriers are described, and data from the Manufacturing Energy Consumption Survey are used to estimate potential electricity savings from industrial energy efficiency measures. Overcoming difficulties to effective program implementation is worthwhile, since rough estimates indicate a substantial potential for electricity savings. The report categorizes types of DSM programs, presents several examples of each type, and explores elements of successful programs. Two in-depth case studies (of Boise Cascade and of Eli Lilly and Company) illustrate two types of effective DSM programs. Interviews with staff from state public utility commissions indicate the current thinking about the status and future of industrial DSM programs. Finally, the research report also includes a comprehensive bibliography, a description of technical assistance programs, and an example of a methodology for evaluating potential or actual savings from projects.

  11. Side-Chain-Induced Rigid Backbone Organization of Polymer Semiconductors through Semifluoroalkyl Side Chains.

    Science.gov (United States)

    Kang, Boseok; Kim, Ran; Lee, Seon Baek; Kwon, Soon-Ki; Kim, Yun-Hi; Cho, Kilwon

    2016-03-23

    While high-mobility p-type conjugated polymers have been widely reported, high-mobility n-type conjugated polymers are still rare. In the present work, we designed semifluorinated alkyl side chains and introduced them into naphthalene diimide-based polymers (PNDIF-T2 and PNDIF-TVT). We found that the strong self-organization of these side chains induced a high degree of order in the attached polymer backbones by forming a superstructure composed of "backbone crystals" and "side-chain crystals". This phenomenon was shown to greatly enhance the ordering along the backbone direction, and the resulting polymers thus exhibited unipolar n-channel transport in field-effect transistors with remarkably high electron mobility values of up to 6.50 cm(2) V(-1) s(-1) and with a high on-off current ratio of 10(5).

  12. Analysis of wave resonant effects in-between offshore vessels arranged side-by-side

    OpenAIRE

    Dinoi, Pasquale

    2016-01-01

    La predicción de la interacción hidrodinámica entre dos cuerpos flotantes en la configuración side-by-side (lado-a-lado) se ha convertido en un importante y complicado problema en los últimos años. Esta situación es relevante cuando se trata de tomar decisiones sobre la viabilidad de una serie de operaciones offshore, principalmente relacionadas con el proceso de transferencia de carga líquida entre dos cascos. Esta tesis se profundiza en algunos aspectos hidrodinámico relevantes que surgen c...

  13. The Variation of Interface Formation with Slurry Viscosity Change in Side-By-Side Tape Casting

    DEFF Research Database (Denmark)

    Bulatova, Regina; Jabbari, Masoud; Andersen, Kjeld Bøhm;

    Homogenous and flexible adjacently graded tapes were produced by casting the organic-based slurries simultaneously. To develop side-by-side tape casing (SBSTC), the material optimization, modernization of the doctor blade design, and parameters control of such processes as casting, drying, de......-bindering and sintering were studied. Solvent and binder concentrations were varied in order to optimize co-casting flow, as well as the drying and sintering shrinkage. Tapes were evaluated in terms of rheological behavior of the slurries, the green and sintered tape microstructure, the quality of the interface area...

  14. Grammars with two-sided contexts

    Directory of Open Access Journals (Sweden)

    Mikhail Barash

    2014-05-01

    Full Text Available In a recent paper (M. Barash, A. Okhotin, "Defining contexts in context-free grammars", LATA 2012, the authors introduced an extension of the context-free grammars equipped with an operator for referring to the left context of the substring being defined. This paper proposes a more general model, in which context specifications may be two-sided, that is, both the left and the right contexts can be specified by the corresponding operators. The paper gives the definitions and establishes the basic theory of such grammars, leading to a normal form and a parsing algorithm working in time O(n^4, where n is the length of the input string.

  15. Constraining the dark side with observations

    Energy Technology Data Exchange (ETDEWEB)

    Diez-Tejedor, Alberto [Dpto. de Fisica Teorica, Universidad del PaIs Vasco, Apdo. 644, 48080, Bilbao (Spain)

    2007-05-15

    The main purpose of this talk is to use the observational evidences pointing out to the existence of a dark side in the universe in order to infer some of the properties of the unseen material. We will work within the Unified Dark Matter models, in which both, Dark Matter and Dark Energy appear as the result of one unknown component. By modeling effectively this component with a classical scalar field minimally coupled to gravity, we will use the observations to constrain the form of the dark action. Using the flat rotation curves of spiral galaxies we will see that we are restringed to the use of purely kinetic actions, previously studied in cosmology by Scherrer. Finally we arrive to a simple action which fits both cosmological and astrophysical observations.

  16. Pathologic overproduction: the bad side of adenosine.

    Science.gov (United States)

    Borea, Pier Andrea; Gessi, Stefania; Merighi, Stefania; Vincenzi, Fabrizio; Varani, Katia

    2017-03-02

    Adenosine is an endogenous ubiquitous purine nucleoside, increased by hypoxia, ischemia and tissue damage that mediates a number of physiopathological effects by interacting with four G-protein-coupled receptors, identified as A1 , A2A , A2B , and A3 . Physiological and acutely-increased adenosine is associated with beneficial effects mostly including vasodilation and decrease of inflammation. In contrast chronic overproduction of adenosine occurs in important pathological states, where long lasting increases in the nucleoside levels are responsible for the bad side of adenosine associated with chronic inflammation, fibrosis and organ damage. In this review we describe and critically discuss the pathologic overproduction of adenosine analysing when, where and how adenosine exerts its detrimental effects through the body.

  17. Development of Crashworthy Bottom and Side Structures

    DEFF Research Database (Denmark)

    Naar, H.; Kujala, P.; Simonsen, Bo Cerup;

    2002-01-01

    structures. The first structure is a conventional double bottom. In the second structure (presently protected through a patent) the bottom plating is stiffened with hat-profiles instead of bulb profiles. In the third structure the outer shell is an all-steel sandwich panel. In the fourth structure the bottom......The purpose of this work is to compare the resistance to damage of various types of double bottom structures in a stranding event. The results can also be interpreted as the crashworthiness of side structures penetrated by a striking vessel in a collision event. The comparative analyses are made...... by use of a commercial, explicit finite element program. The ship bottom is loaded with a conical indenter with a rounded tip, which is forced laterally into the structures in different positions. The aim is to compare resistance forces, energy absorption and penetration to fracture for four different...

  18. Narrating narcolepsy--centering a side effect.

    Science.gov (United States)

    Lundgren, Britta

    2015-01-01

    The mass-vaccination with Pandemrix was the most important preventive measure in Sweden during the A(H1N1) influenza pandemic of 2009-2010, and covered 60% of the population. From 2010, an increased incidence of the neurological disease narcolepsy was reported, and an association with Pandemrix was affirmed for more than 200 children and young adults. The parental experience of this side effect provided a starting point for a collectively shaped critical narrative to be acted out in public, but also personalized narratives of continual learning about the disease and its consequences. This didactic functionality resulted in active meaning-making practices about how to handle the aftermath--using dark humor, cognitive tricks, and making themselves and their children's bodies both objects and subjects of knowledge. Using material from interviews with parents, this mixing of knowledge work and political work, and the potential for reflective consciousness, is discussed.

  19. Industrial demand side management: A status report

    Energy Technology Data Exchange (ETDEWEB)

    Hopkins, M.F.; Conger, R.L.; Foley, T.J. [and others

    1995-05-01

    This report provides an overview of and rationale for industrial demand side management (DSM) programs. Benefits and barriers are described, and data from the Manufacturing Energy Consumption Survey are used to estimate potential energy savings in kilowatt hours. The report presents types and examples of programs and explores elements of successful programs. Two in-depth case studies (from Boise Cascade and Eli Lilly and Company) illustrate two types of effective DSM programs. Interviews with staff from state public utility commissions indicate the current thinking about the status and future of industrial DSM programs. A comprehensive bibliography is included, technical assistance programs are listed and described, and a methodology for evaluating potential or actual savings from projects is delineated.

  20. The quantum capacity with symmetric side channels

    CERN Document Server

    Smith, G; Winter, A; Smith, Graeme; Smolin, John A.; Winter, Andreas

    2006-01-01

    We present an upper bound for the quantum channel capacity that is both additive and convex. Our bound can be interpreted as the capacity of a channel for high-fidelity communication when assisted by the family of all channels mapping symmetrically to their output and environment. The bound seems to be quite tight, and for degradable quantum channels it coincides with the unassisted channel capacity. Using this symmetric side channel capacity, we find new upper bounds on the capacity of the depolarizing channel. We also briefly indicate an analogous notion for distilling entanglement using the same class of (one-way) channels, yielding one of the few genuinely 1-LOCC monotonic entanglement measures.

  1. The dark side of SAPHO syndrome.

    Science.gov (United States)

    Henriques, Celia Coelho; Sousa, Mónica; Panarra, António; Riso, Nuno

    2011-12-21

    SAPHO syndrome (synovitis, acne, pustulosis, hyperostosis and osteitis) is a relatively rare entity. The therapeutic approach of patients with SAPHO syndrome has included multiple drugs with varying success and incoherence responses. The therapy is still empirical today. SAPHO syndrome is commonly treated with non-steroidal anti-inflammatory drugs, bisphophonates and non-biologic disease modifying antirheumatic drugs. Recent reports showed successful treatment with tumour necrosis factor α (TNF α) antagonists, but there is still a dark side of SAPHO syndrome including a subgroup of patient's refractory to all the treatments that have been empirically experienced. A clinical report of a patient with SAPHO syndrome with 12 years of evolution is described. All the therapeutic approaches, including anti TNF α therapy, have not prevented the clinical and radiographic progression of the disease. Given that the disease affects mostly younger patients, new therapeutic strategies are necessary in order to avoid potentially irreversible joint and bone lesions.

  2. The Siding Spring Hazard at Mars

    Science.gov (United States)

    Kelley, Michael; Bauer, James; Bodewits, Dennis; Farnham, Tony; Li, Jian-Yang; Samarasinha, Nalin; Stevenson, Rachel; Tricarico, Pasquale

    2014-02-01

    Comet C/2013 A1 (Siding Spring) will pass Mars at the extremely close distance of 136,000 km in Oct 2014, giving Mars orbiting spacecraft an up-close and unprecedented view of this dynamically new comet. However, 100 minutes after the closest approach to the nucleus, Mars passes within 30,000 km of the comet's orbit. Here, large dust grains may be found on impacting trajectories, potentially posing a fatal hazard to the spacecraft. Such large grains must be ejected from the comet nucleus well before the time of encounter. Therefore, we propose IRAC imaging of this comet to assess the present-day gas production rate, which will aid dust impact hazard assessment.

  3. Esomeprazole induced galactorrhea: a novel side effect.

    Science.gov (United States)

    Pipaliya, Nirav; Solanke, Dattatray; Rathi, Chetan; Patel, Ruchir; Ingle, Meghraj; Sawant, Prabha

    2016-02-01

    Proton pump inhibitors (PPIs) are one of the most frequently prescribed medications across the globe. Esomeprazole is the S-isomer of omeprazole, and it is currently the most widely prescribed PPI. The safety profile of esomeprazole is extremely favorable with only minor side effects, like headache and diarrhea, that are encountered in day to day practice. We report a case of a young female with symptoms of gastroesophageal reflux disease who developed galactorrhea after starting esomeprazole therapy. Resolution of galactorrhea after stopping the drug and self-rechallenge by the patient herself with reappearance of galactorrhea confirmed the culprit to be esomeprazole only. We postulate that esomeprazole may have a mild inhibitory effect on CYP3A4, which leads to decreased metabolism of estrogen, thereby increasing serum estrogen levels. Estrogen causes stimulation and production of prolactin release, which results in development of galactorrhea. This is the first case of esomeprazole induced galactorrhea, to the best of our knowledge.

  4. The two sides of silicon detectors

    CERN Document Server

    Devine, S R

    2001-01-01

    /p/n sup + and essentially two p-n junctions within one device. With increasing bias voltage, as the electric field is extending into the detector bulk from opposite sides of the silicon detector, there are two distinct depletion regions that collect charge signal independently. Summing the signal charge from the two regions, one is able to reconstruct the initial energy of the incident particle. From Transient Current measurements it is apparent that E-field manipulation is possible by excess carrier injection, enabling a high enough E-field to extend across the width of the detector, allowing for efficient charge collection. Results are presented on in situ irradiation of silicon detector's at cryogenic temperature. The results show that irradiation at cryogenic temperatures does not detrimentally effect a silicon detectors performance when compared to its irradiation at room temperature. Operation of silicon devices at cryogenic temperatures offers the advantage of reducing radiation-induced leakage curren...

  5. Side-Scan-Sonar Points for Hudson River, NY

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Side Scan Point Files. These points correspond to individual pings which produced hte side-scan-sonar backscatter imagery. Sonar data were collected November 6 to...

  6. Managing Chemotherapy Side Effects: Fatigue (Feeling Weak and Very Tired)

    Science.gov (United States)

    ... nurse about other exercises that can help. Stretching, yoga, or Tai Chi help some people. Questions to ... NCI has a series of 18 Chemotherapy Side Effects Sheets at: www.cancer.gov/chemo-side-effects

  7. LARGE EDDY SIMULATION AND SPECTRUM ANALYSIS OF FLOW AROUND TWO SQUARE CYLINDERS ARRANGED SIDE BY SIDE

    Institute of Scientific and Technical Information of China (English)

    魏英杰; 朱蒙生; 何钟怡

    2004-01-01

    Large eddy simulation cooperated with the second order full extension ETG (Euler-Taylor-Galerkin) finite element method was applied to simulate the flow around two square cylinders arranged side by side at a spacing ratio of 1.5. The second order full extension ETG finite element method was developed by Wang and He. By means of Taylor expansion of terms containing time derivative, time derivative is replaced by space derivative. The function of it is equal to introducing an artificial viscosity term. The streamlines of the flow at different moments were obtained. The time history of drag coefficient, lift coefficient and the streamwise velocity on the symmetrical points were presented. Furthermore, the symmetrical problem of the frequency spectrum of flow around two square cylinders arranged side by side were studied by using the spectral analysis technology. The data obtained at the initial stage are excluded in order to avoid the influence of initial condition on the results. The power spectrums of drag coefficient, lift coefficient, the streamwise velocity on the symmetrical points were analyzed respectively.The results show that although the time domain process of dynamic parameters is nonsymmetrical, the frequency domain process of them is symmetrical under the symmetrical boundary conditions.

  8. HYDRODYNAMIC INTERACTION BETWEEN FLNG VESSEL AND LNG CARRIER IN SIDE BY SIDE CONFIGURATION

    Institute of Scientific and Technical Information of China (English)

    ZHAO Wen-hua; YANG Jian-min; HU Zhi-qiang

    2012-01-01

    The Floating Liquefied Natural Gas (FLNG) is a new type of floating platform for the exploitation of stranded offshore oil/gas fields.The side by side configuration for the FLNG vessel and the LNG carrier arranged in parallel is one of the possible choices for the LNG offloading.During the offioading operations,the multiple floating bodies would have very complex responses due to their hydrodynamic interactions.In this study,numerical simulations of multiple floating bodies in close proximity in the side by side offioading configuration are carried out with the time domain coupled analysis code SIMO.Hydrodynamic interactions between the floating bodies and the mechanical coupling effects between the floating bodies and their connection systems are included in the coupled analysis model.To clarify the hydrodynamic effects of the two vessels,numerical simulations under the same environmental condition are also conducted without considering the hydrodynamic interactions,for comparison.It is shown that the hydrodynamic interactions play an important role in the low frequency motion responses of the two vessels,but have little effect on the wave frequency motion responses.In addition,the comparison results also show that the hydrodynamic interactions can affect the loads on the connection systems.

  9. The Light Side and The Dark Side of the Milky Way Halo

    Science.gov (United States)

    Kafle, Prajwal R.; Sharma, Sanjib; Lewis, Geraint F.; Bland-Hawthorn, Joss

    2014-01-01

    We present our recent measurement of the kinematics of the Milky Way stellar halo (Light Side) and the derived mass of the dark matter halo (Dark Side) using the Jeans analysis. A tangential dip in the velocity anisotropy profile at r ~ 17 kpc (Kafle et al. 2012), and a distinct difference of ~65 kms-1 in the mean azimuthal velocity and the r.m.s dispersion of the most metal-rich and the metal-poor Blue Horizontal Branch stars we find (Kafle et al. 2013) are reported. The implications of this on the current controversial issue of an existence of the two-components in the halo are also discussed. Aided with the kinematic measurements of the light side, we demonstrate how we infer the dynamical property of the dark side. Considering a realistic three component galaxy model (Hernquist bulge, Miyamoto-Nagai disk and NFW halo), we estimate the virial mass of the Galaxy to be M vir = 1.2+0.5 -0.4 × 1012 M ⊙ (Kafle et al. 2012). We also show that the rotation curve of the Galaxy has undulations similar to what have also been seen in the studies of the HI gas (Sofue et al. 2009).

  10. Interaction of Gap Flow With Flapping Dynamics of Two Side-by-Side Elastic Foils

    Science.gov (United States)

    Gurugubelli, Pardha S.; Jaiman, Rajeev K.

    2016-11-01

    We present a numerical analysis on the interaction between two side-by-side elastic foils with their leading edges clamped and the gap flow between them. We perform systematic parametric direct numerical simulations as a function of nondimensional bending rigidity, KB ∈ [ 1 ×10-4 , 3 ×10-3 ] and mass-ratio, m* ∈ [ 0 . 05 , 0 . 2 ] , for a fixed gap, dp = 0 . 2 / L , at the leading edge and Reynolds number, Re = 1000 to explain the underlying physical mechanism behind the in-phase and out-of-phase coupled flapping modes. The parametric simulations show that the parallel foil system exhibits predominant out-of-phase coupling for low mass-ratio m* 0 . 1 . We also show that the two side-by-side elastic foils always exhibit out-of-phase coupling initially irrespective of whether the fully developed flapping show out-of-phase or in-phase coupled mode. Finally, we show that the transition from the initial out-of-phase to stable in-phase is characterized by loss of gap flow symmetric stability to undergo oscillations at the gap exit.

  11. Three--dimensional Instability in the Wake of Two Side--by--side Square Cylinders

    Science.gov (United States)

    Choi, Choon-Bum; Jang, Yong-Jun; Yang, Kyung-Soo

    2011-11-01

    Three-dimensional instability in the flow past two square cylinders in side-by-side arrangements has been numerically studied via a Floquet stability analysis. The distance between the neighboring faces of the two cylinders (G) is the key parameter which affects the secondary instability under consideration. In this talk, we present the critical Reynolds number for the 3D instability and the spanwise wave number corresponding to the most unstable (or least stable) wave for each G. When the two cylinders are close to each other, the Floquet mode resembles mode A of flow past a single cylinder. For large G, the Floquet mode for each cylinder is independent of the neighboring cylinder as expected. In the range of intermediate G, interference of the two wakes is clearly reflected in the Floquet mode. We also discuss about the effect of gap flow, and visualization of the dominant 3D vortical structures is provided by using Q contours. Our results shed light on a complete understanding of the onset of 3D instability in the presence of two side-by-side square cylinders. This work was supported by Korea Railroad Research Institute (Research Title: The study of standardization for urban railway facilities (SW 11002)).

  12. Quantitative flow characteristics for side-by-side square cylinders via PIV

    Directory of Open Access Journals (Sweden)

    Dogan Sercan

    2012-04-01

    Full Text Available In this study, instantaneous and time-averaged flow structures downstream of the sharp-edged single and two and three side-by-side square cylinders (SCs immersed in a uniform open channel water flow were studied by a technique of particle image velocimetry (PIV. Experimental results of wake flow structures were presented for gap ratios (G/D in the range of 1.0”G/D”3.0 for Reynolds number values of 1050, 2450 and 3400. Flow structures depending on the square cylinder (SC configurations and Reynolds number were discussed. It has been found that the development of the vortex shedding as well as the flow structure were substantially altered for side-by-side SCs comparing to the single SC. Asymmetrical and biased wake structures were observed because of the jetlike flow between the SCs for two SCs cases for the gap ratio less than 2.0. Depending on the gap spacing between the SCs, the interaction results of time2 averaged vorticity, velocity vector field, Reynolds stress correlations and streamline patterns in the wake region form a distinguished flow structure. Strouhal numbers for the single square cylinder for 1050≤Re≤3400 are found in the range of 0.12-0.13. The present results have supported the previous works by providing detailed quantitative experimental information with PIV in the wake region of the SC and might be helpful for validation of numerical studies and designers.

  13. NUMERICAL SIMULATION OF FLOW OVER TWO SIDE-BY-SIDE CIRCULAR CYLINDERS

    Institute of Scientific and Technical Information of China (English)

    SARVGHAD-MOGHADDAM Hesam; NOOREDIN Navid; GHADIRI-DEHKORDI Behzad

    2011-01-01

    In the present paper,the unsteady,viscous,incompressible and 2-D flow around two side-by-side circular cylinders was simulated using a Cartesian-staggered grid finite volume based method.A great-source term technique was employed to identify the solid bodies (cylinders) located in the flow field and boundary conditions were enforced by applying the ghost-cell technique.Finally,the characteristics of the flow around two side-by-side cylinders were comprehensively obtained through several computational simulations.The computational simulations were performed for different transverse gap ratios (1.5≤T/D≤4) in laminar (Re =100,200 ) and turbulent (Re =104) regimes,where T and D are the distance between the centers of cylinders and the diameter of cylinders,respectively.The Reynolds number is based on the diameter of cylinders,D.The pressure field and vorticity distributions along with the associated streamlines and the time histories of hydrodynamic forces were also calculated and analyzed for different gap ratios.Generally,different flow patterns were observed as the gap ratio and Reynolds number varied.Accordingly,the hydrodynamic forces showed irregular variations for small gaps while they took a regular pattern at higher spacing ratios.

  14. [Investigation of permeability of intranasal formulations using Side-Bi-Side horizontal diffusion cell].

    Science.gov (United States)

    Horváth Tamás; Ambrus, Rita; Szabóné, Révész Piroska

    2015-01-01

    Nowadays the nasal route has received a great attention as a reliable administration for the systemic administration. In the Department of Pharmaceutical Technology, University of Szeged, the main research work is the design and development of innovative nasal formulations, which can open new possibilities for some well-known agents and may also help some drug-candidates delivery problems. The aim of this work was to present some reliable models for investigation of permeability, such as Spectra/Por Dialisys Membran, ZelluTrans/Roth Mini Dialyzer, μFLUX diffusion Cell, Navicyte Vertical and Horizontal Diffusion Chamber System and In-line Cell. In addition, the horizontal membrane diffusion model (Side-Bi-Side) was used to investigate in vitro and ex vivo studies of permeability of meloxicam in comparison with the vertical diffusion cell (Franz). The present study investigated the meloxicam in different dosage forms (powder, spray, gel). It was found that the Side-Bi-Side cell is suitable to test the nasal formulations, but the uniform distribution of the active substance cannot be ensured in donor place by increasing the viscosity of the compositions, therefore the Franz cell is recommended for investigation of nasal gel. Previous measurement cannot be found related to this topic.

  15. Market definition in two-sided markets : Theory and practice

    NARCIS (Netherlands)

    Filistrucchi, L.; Geradin, D.A.A.G.; van Damme, E.E.C.; Affeldt, P.

    2014-01-01

    Drawing from the economics of two-sided markets, we provide suggestions for the definition of the relevant market in cases involving two-sided platforms, such as media outlets, online intermediaries, payment cards companies, and auction houses. We also discuss when a one-sided approach may be harmle

  16. Organizational mediators siding with or against the powerful party?

    NARCIS (Netherlands)

    de Dreu, C.K.W.; Laskewitz, P.; van de Vliert, E.

    1994-01-01

    Examined whether, instead of being impartial, a mediator may side with one party as a function of the disputants' power differences (power balancing theory), the mediator's legitimacy judgments (siding theory), or the disputants' capacity to sanction the mediator (siding theory). A questionnaire stu

  17. Improved side information generation for distributed video coding

    DEFF Research Database (Denmark)

    Huang, Xin; Forchhammer, Søren

    2008-01-01

    As a new coding paradigm, distributed video coding (DVC) deals with lossy source coding using side information to exploit the statistics at the decoder to reduce computational demands at the encoder. The performance of DVC highly depends on the quality of side information. With a better side info...

  18. 14 CFR 23.363 - Side load on engine mount.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Side load on engine mount. 23.363 Section....363 Side load on engine mount. (a) Each engine mount and its supporting structure must be designed for a limit load factor in a lateral direction, for the side load on the engine mount, of not less...

  19. Side-to-side growth discrepancies in children with hemiplegic cerebral palsy: association with function, activity and social participation

    OpenAIRE

    Marise Bueno Zonta; Amâncio Ramalho-Júnior; Marilene Puppi; Isac Bruck,; Neiva Magdalena; Muzzolon, Sandra Regina B.; Arnolfo Carvalho-Neto; Lúcia H Coutinho dos Santos

    2014-01-01

    Objective: Evaluate side-to-side discrepancies in children with hemiplegic cerebral palsy (HCP), and investigate associations of these discrepancies with patients’ age at initiation of physical therapy, motor and cognitive function, and degree of activities and social participation. Method: We obtained eight side-to-side measurements from 24 HCP children with mean age 49.3±5.2 months. Results: Early initiation of physical therapy was associated with lower discrepancy in hand length (p=0.037)....

  20. Flow and wall shear stress in end-to-side and side-to-side anastomosis of venous coronary artery bypass grafts

    Directory of Open Access Journals (Sweden)

    Poulikakos Dimos

    2007-09-01

    Full Text Available Abstract Purpose Coronary artery bypass graft (CABG surgery represents the standard treatment of advanced coronary artery disease. Two major types of anastomosis exist to connect the graft to the coronary artery, i.e., by using an end-to-side or a side-to-side anastomosis. There is still controversy because of the differences in the patency rates of the two types of anastomosis. The purpose of this paper is to non-invasively quantify hemodynamic parameters, such as mass flow and wall shear stress (WSS, in end-to-side and side-to-side anastomoses of patients with CABG using computational fluid dynamics (CFD. Methods One patient with saphenous CABG and end-to-side anastomosis and one patient with saphenous CABG and side-to-side anastomosis underwent 16-detector row computed tomography (CT. Geometric models of coronary arteries and bypasses were reconstructed for CFD analysis. Blood flow was considered pulsatile, laminar, incompressible and Newtonian. Peri-anastomotic mass flow and WSS were quantified and flow patterns visualized. Results CFD analysis based on in-vivo CT coronary angiography data was feasible in both patients. For both types of CABG, flow patterns were characterized by a retrograde flow into the native coronary artery. WSS variations were found in both anastomoses types, with highest WSS values at the heel and lowest WSS values at the floor of the end-to-side anastomosis. In contrast, the highest WSS values of the side-to-side anastomosis configuration were found in stenotic vessel segments and not in the close vicinity of the anastomosis. Flow stagnation zones were found in end-to-side but not in side-to-side anastomosis, the latter also demonstrating a smoother stream division throughout the cardiac cycle. Conclusion CFD analysis of venous CABG based on in-vivo CT datasets in patients was feasible producing qualitative and quantitative information on mass flow and WSS. Differences were found between the two types of anastomosis

  1. Side Chain Engineering in Solution-Processable Conjugated Polymers

    KAUST Repository

    Mei, Jianguo

    2014-01-14

    Side chains in conjugated polymers have been primarily utilized as solubilizing groups. However, these side chains have roles that are far beyond. We advocate using side chain engineering to tune a polymer\\'s physical properties, including absorption, emission, energy level, molecular packing, and charge transport. To date, numerous flexible substituents suitable for constructing side chains have been reported. In this Perspective article, we advocate that the side chain engineering approach can advance better designs for next-generation conjugated polymers. © 2013 American Chemical Society.

  2. Radio on the Other Side of Time

    Directory of Open Access Journals (Sweden)

    Alicia TAPIA LÓPEZ

    2016-06-01

    Full Text Available On October 30, 1938, Orson Welles aired the radio drama The War of the Worlds on the CBS Radio network, adapting the science-fiction novel by the British writer H. G. Wells. During the broadcast, listeners became stricken with panic, believing that the Earth was actually being invaded by giant snake-like Martians launching rays of fire down on humans. Welles was a groundbreaking figure whose trickery exploited the technological novelty of the radio to its fullest, adapting classic texts in ways that exploited the opportunities afforded by this new medium. Over the years, this radio classic has been adapted a number of times, though none has seized on the technological advances of our times. Drawing on the most salient innovations seen in Internet radio, this article creates an imaginary scenario that replicates Orson Welles’s work in the present day, when the Internet has become a channel for broadcasting and hyperlinks have brought different media together. The text is an exploration of the other side of time, where transmedia storytelling facilitates the exchange of stories among consumers, and broadcast programming is no longer linear.

  3. The Darker Side of the Renaissance

    Directory of Open Access Journals (Sweden)

    Walter Mignolo

    2009-01-01

    Full Text Available The Darker Side of the Renaissance focuses on coloniality rather than on Europe’s witch and alchemist hunt. Today I would dare to say also that this expression refers us to the historical foundation of coloniality. At the same time, coloniality statement is called into question, as well as the distinction between the known object and the knowing subject, an assumption on which the Eurocentric project of “modernity” and “modernization” disciplines lie. The preface marks the enunciation with which the statement is stated. That is, it rejects the "point zero epistemology" denounced by Santiago Castro-Gómez. This means the reader should be always pay attention to the ennunciation s/he states him/herself, to the hand drawing the hand. Those of us dwelling at Abya-Yala/America are surrounded by the historical foundation of modernity/coloniality, we are a living part of that process, which only “scientific” alignment can make us believe we are looking at something (e.g., colonization touching what we are today

  4. Adaptive Optics Simulations for Siding Spring

    CERN Document Server

    Goodwin, Michael; Lambert, Andrew

    2012-01-01

    Using an observational derived model optical turbulence profile (model-OTP) we have investigated the performance of Adaptive Optics (AO) at Siding Spring Observatory (SSO), Australia. The simulations cover the performance for AO techniques of single conjugate adaptive optics (SCAO), multi-conjugate adaptive optics (MCAO) and ground-layer adaptive optics (GLAO). The simulation results presented in this paper predict the performance of these AO techniques as applied to the Australian National University (ANU) 2.3 m and Anglo-Australian Telescope (AAT) 3.9 m telescopes for astronomical wavelength bands J, H and K. The results indicate that AO performance is best for the longer wavelengths (K-band) and in the best seeing conditions (sub 1-arcsecond). The most promising results are found for GLAO simulations (field of view of 180 arcsecs), with the field RMS for encircled energy 50% diameter (EE50d) being uniform and minimally affected by the free-atmosphere turbulence. The GLAO performance is reasonably good over...

  5. Side effects of endobronchial laser treatment

    Energy Technology Data Exchange (ETDEWEB)

    Dierkesmann, R.; Huzly, A.

    1985-03-01

    Side effects that have occurred in over 250 endobronchial laser treatments are reported. The laser has been used in severe tracheal and in bronchial obstructions. In two cases significant bleeding had to be treated with tamponade. In one patient an emphysema of the mediastinum developed, in 2 further patients a small pneumothorax. Perforation of the airway was not detected and no special treatment was necessary. Three patients with life-threatening tracheal stenoses and one patient with severe stenosis of both the mainstem bronchi due to metastasis in the bifurcation lymph node had a large defect in the tracheal or bronchial wall with a deep necrosis five to twelve weeks after laser treatment; all these patients had extensive radiotherapy in addition. One patient died due to severe respiratory insufficiency, probably caused by smoke intoxication. After the laser treatment, rubber-like fibrin-rich plaques may develop, which can lead to life-threatening obstructions of the airway. It is recommended that laser bronchoscopy should be performed with the rigid bronchoscope. After treatment of tracheal lesion an endoscopic check must be performed within 24 hours. The combination of laser treatment and radiotherapy seems to involve a certain risk of large defects in the bronchial wall due to necrosis of the tumor.

  6. Interference Alignment: A one-sided approach

    CERN Document Server

    Ghauch, Hadi G

    2011-01-01

    Interference Alignment (IA) is the process of designing signals in such a way that they cast overlapping shadows at their unintended receivers, while remaining distinguishable at the intended ones. Our goal in this paper is to come up with an algorithm for IA that runs at the transmitters only (and is transparent to the receivers), that doesn't require channel reciprocity, and that alleviates the need to alternate between the forward and reverse network as is the case in Distributed IA (Gomadam, Cadambe, Jafar 08'), thereby inducing significant overhead in certain environments where the channel changes frequently. Most importantly, our effort is focused on ensuring that this one-sided approach does not degrade the performance of the system w.r.t. Distributed IA (since it cannot improve it). As a first step, we model the interference in each receiver's desired signal as a function of the transmitters' beamforming vectors. We then propose a simple steepest descent (SD) algorithm and use it to minimize the inter...

  7. Incentives for demand-side management

    Energy Technology Data Exchange (ETDEWEB)

    Reid, M.W.; Brown, J.B. [Barakat and Chamberlin, Inc., Oakland, CA (United States)

    1992-01-01

    This report is the first product of an ongoing project to monitor the efforts of states to remove regulatory barriers to, and provide financial incentives for, utility investment in demand-side management (DSM) resources. The project was commissioned by the National Association of Regulatory Utility Commissioners (NARUC) in response to growing interest among regulators for a comprehensive survey of developments in this area. Each state report beings with an overview of the state`s progress toward removing regulatory barriers and providing incentives for DSM. Information is organized under five headings: status; IRP regulations and practice; current treatment of DSM, directions and trends; commission contact person. Where applicable, each overview is followed by one or more sections that report on specific incentive proposals or mechanisms within the state. Information on each proposal or mechanism is organized under eight headings. A notation on each page identifies the utility or other group associated with the proposal or mechanism. The eight headings are as follows: status; background; treatment of cost recovery; treatment of lost revenues/decoupling; treatment of profitability; other features; issues, and additional observations.

  8. Incentives for demand-side management

    Energy Technology Data Exchange (ETDEWEB)

    Reid, M.W.; Brown, J.B. (Barakat and Chamberlin, Inc., Oakland, CA (United States))

    1992-01-01

    This report is the first product of an ongoing project to monitor the efforts of states to remove regulatory barriers to, and provide financial incentives for, utility investment in demand-side management (DSM) resources. The project was commissioned by the National Association of Regulatory Utility Commissioners (NARUC) in response to growing interest among regulators for a comprehensive survey of developments in this area. Each state report beings with an overview of the state's progress toward removing regulatory barriers and providing incentives for DSM. Information is organized under five headings: status; IRP regulations and practice; current treatment of DSM, directions and trends; commission contact person. Where applicable, each overview is followed by one or more sections that report on specific incentive proposals or mechanisms within the state. Information on each proposal or mechanism is organized under eight headings. A notation on each page identifies the utility or other group associated with the proposal or mechanism. The eight headings are as follows: status; background; treatment of cost recovery; treatment of lost revenues/decoupling; treatment of profitability; other features; issues, and additional observations.

  9. The Dark side of World of Warcraft

    DEFF Research Database (Denmark)

    Larsen, Lasse Juel

    the look of ‘the other’. ‘The look’ can following this argument be perceived as an instrument of (self)-becoming. Becoming aware of ourselves through the look of ‘the other’ also means ‘the other’ holds a formative power over us which can be understood as an instrument of control, an always present way...... understand, perceive or conceptualise fellow players in-side the game world. The analysis of ‘the other’ in WoW rests upon Jean-Paul Sartre’s phenomenological description of ‘the other’ through ‘the look’ in Being and Nothingness (1992). According to Sartre do living beings become aware of themselves through......’s epistemology not only serve to describe the state of ‘the other’ and the social disciplining impact of the spatial design on player perception and behaviour in WoW, it also aims at showing a connection between Sartre and Foucault’s analysis of ‘the look’. This leads to the tentative conclusion that ‘the look...

  10. [The democratic side of science-fiction].

    Science.gov (United States)

    Lecellier, Charles-Henri

    2011-04-01

    Suspicion towards technological advances has progressively grown during the xx(th) century. However, in the XXI(st) century, reading the NBIC (nanotechnology, biotechnology, information technology and cognitive science) report of the National Science Foundation, we can note that science has caught up with science fiction. These changes in public mentality on one side and in scientific capacities on the other argue for an evolution of the debate on sciences. The recent example of the national debate on nanotechnology in France has clearly shown that the public is no longer waiting for additional sources of scientific knowledge but rather waiting for the recognition of its authority to participate in the definition of the national R&D priority and associated scientific strategies. This is all the more legitimate that these strategies will have profound impact on the future of our societies and therefore cannot be decided only by scientists. Hence, it is crucial to identify innovative tools promoting debate on sciences and their technological spin-off. Here, we contend that science fiction has major assets that could face this challenge and facilitate the dialogue between sciences and society.

  11. The effectiveness of side marker lamps: an experimental study.

    Science.gov (United States)

    Theeuwes, J; Alferdinck, J W

    1997-03-01

    The present experiment investigated the effect of small amber lamps mounted near the front and rear on each side of a passenger car-so called side marker lamps-on visual detection and recognition of passenger cars in complex nighttime environments. It was determined whether cars equipped with side marker lamps are detected and recognized earlier and more accurately than cars without side marker lamps. Subjects were presented with slides of natural nighttime scenes in which a car, either with or without side marker lamps, viewed from its side, approaching from a side street, was either present or not. Subjects determined as fast as possible whether a car was present or not. Reaction time measures (speed and accuracy) indicated that both under clear and fog visibility conditions, a car equipped with side marker lamps was detected and recognized earlier and more accurately than a car without side marker lamps. The results indicate that side marker lamps increase both lateral conspicuity and recognizability suggesting that side marker lamps may be effective in reducing the number of nighttime angle collisions.

  12. Measured Data Processing Method For Relative Motions Between Two Side-by-side Ships

    Directory of Open Access Journals (Sweden)

    Ping-an Shi

    2013-01-01

    Full Text Available In order to design and implement a wave compensation system to reduce the relative motion between two side-by-side ships in waves, a new method to process measured data of ship model test with contact measurement to study the characteristics of relative motion was presented. The reference co-ordinate systems and relative motions were defined, and the scheme of the model test was described. Then the Empirical Mode Decomposition(EMD adaptive filter were designed, the frequency domain integration transform method based upon Fast Fourier Transform(FFT were established. The procedure to transform acceleration signal into displacement was proposed and verified, and the processing results with and without EMD adaptive filter were compared. Finally, the relative motions consistent with reality were acquired, which indicates this method is effective for measured data processing.

  13. Wave Drift Forces on Two Floating Bodies Arranged Side by Side

    Institute of Scientific and Technical Information of China (English)

    Wenyang Duan; Binbin Zhao

    2011-01-01

    An innovative hydrodynamic theory and numerical model were developed to help improve the efficiency,accuracy,and convergence of the numerical prediction of wave drift forces on two side-by-side deepwater floating bodies.The wave drift forces were expressed by the double integration of source strength and the corresponding Green function on the body surface,which is consistent with the far field formula based on momentum conservation and sharing the advantage of near field calculations providing the drift force on each body.Numerical results were validated through comparing the general far field model and pressure integral model,as well as the middle field model developed using the software HydroStar.

  14. Detection of Left-Sided and Right-Sided Hearing Loss via Fractional Fourier Transform

    Directory of Open Access Journals (Sweden)

    Shuihua Wang

    2016-05-01

    Full Text Available In order to detect hearing loss more efficiently and accurately, this study proposed a new method based on fractional Fourier transform (FRFT. Three-dimensional volumetric magnetic resonance images were obtained from 15 patients with left-sided hearing loss (LHL, 20 healthy controls (HC, and 14 patients with right-sided hearing loss (RHL. Twenty-five FRFT spectrums were reduced by principal component analysis with thresholds of 90%, 95%, and 98%, respectively. The classifier is the single-hidden-layer feed-forward neural network (SFN trained by the Levenberg–Marquardt algorithm. The results showed that the accuracies of all three classes are higher than 95%. In all, our method is promising and may raise interest from other researchers.

  15. Flow Features of Three Side-by-side Circular Cylinders at Low Reynolds Number

    Directory of Open Access Journals (Sweden)

    Liu Junkao

    2016-01-01

    Full Text Available In order to study the fluctuation of kinetic parameter of cylinder matrix in incompressible stationary flow, the flow fluid around three side-by-side circular cylinders are simulated using Immersed Boundary–Lattice Boltzmann method (IB-LBM. Drag and lift force of the three cylinders are investigated as the interval between each cylinder varied from zero to five times of the cylinder diameter. Five flow patterns are defined according to the vortices structure in the downstream of the cylinders. Power spectrum analysis of lift force is developed to explain the vortex patterns. Through the research, we find the strength and phase of the gap flow play an important role in the vortex formatting process. The vortices shedding from different cylinders neutralize and combine in the near wake, contributing a lot to the variation of forces.

  16. Integrated planning in supply chains with buy-side and sell-side marketplaces

    Indian Academy of Sciences (India)

    Roshan Gaonkar; N Viswanadham

    2005-04-01

    In this paper we develop a quadratic programming model for partner selection and planning in integrated supply chain networks embedded with both sell-side and buy-side electronic marketplaces. Such a scenario arises in several practical applications. In particular, we consider a contract manufacturer who procures components from suppliers through a component marketplace and sells its manufactured sub-assemblies to original equipment manufacturers (OEMs), through a sub-assembly marketplace. In these web-enabled supply chains, embedded with upstream and downstream electronic marketplaces, we need methods for online supply-chain partner selection based on pricing and delivery schedules. In this paper, we develop and present such a model that selects partners, synchronizes supply chain activities and optimizes the profit through optimal revenue pricing and cost minimization.

  17. Is right-sided colon cancer different to left-sided colorectal cancer? - a systematic review.

    Science.gov (United States)

    Lee, G H; Malietzis, G; Askari, A; Bernardo, D; Al-Hassi, H O; Clark, S K

    2015-03-01

    Colorectal cancer (CRC) exhibits differences in incidence, pathogenesis, molecular pathways and outcome depending on the location of the tumor. This review focuses on the latest developments in epidemiological and scientific studies, which have enhanced our understanding on the underlying genetic and immunological differences between the proximal (right-sided) colon and the distal (left-sided) colorectum. The different ways in which environmental risk factors influence the pathogenesis of CRC depending on its location and the variations in surgical and oncological outcomes are also discussed in this review. In the current era of personalized medicine, we aim to reiterate the importance of tumor location in management of CRC and the implication on future clinical and scientific research.

  18. Side by side tests of two SDHW systems with solar collectors with and without antireflection treatment

    DEFF Research Database (Denmark)

    Kong, Weiqiang; Han, Jiangong; Perers, Bengt

    2015-01-01

    Two low flow SDHW systems based on mantle tanks are tested side by side in a laboratory test facility for solar heating systems under the same weather and operation conditions. The systems are identical with the exception that one system is equipped with a solar collector with antireflection...... treated glass while the other system has a collector with a normal glass. Measurements of the thermal performance of the two systems have been carried out for a long measuring period. The thermal performances of the systems have also been calculated with a detailed simulation model. There is a good...... agreement between measured and calculated thermal performances for both systems. The extra thermal performance of the system with the solar collector with the anti reflection treated glass cover is a strong function of the solar fraction. In sunny periods with high solar fractions the percentage extra...

  19. SIDE-BY-SIDE TESTS OF DIFFERENTLY DESIGNED EVACUATED TUBULAR COLLECTORS

    DEFF Research Database (Denmark)

    Fan, Jianhua; Dragsted, Janne; Furbo, Simon

    2007-01-01

    Six differently designed evacuated tubular collectors, ETCs, utilizing solar radiation from all directions, have been investigated experimentally. The evacuated tubular solar collectors investigated include one SLL all-glass ETC from Tshinghua Solar Co., four heat pipe ETCs from Sunda Technolgoy Co....... and one all-glass ETC with heat pipe from Exoheat AB. The collectors have been investigated side-by-side in an outdoor test facility for a long period. During the measurements, the operating conditions – such as weather conditions, inlet and mean solar collector fluid temperatures have been the same. Thus...... a direct performance comparison is possible. The results of the measurements will be presented in this paper. Among other things, the influence on the thermal performance of the absorber design will be explained. Further, it will be illustrated how the thermal performances of the different collector types...

  20. The side-to-side fashion for individual distal coronary anastomosis using venous conduit.

    Science.gov (United States)

    Kato, Takayoshi; Tsunekawa, Tomohiro; Motoji, Yusuke; Hirakawa, Akihiro; Okawa, Yasuhide; Tomita, Shinji

    2017-04-01

    Regarding to coronary artery bypass grafting (CABG), the end-to-side anastomosis (ESA) has been performed as a gold standard. Recently, the effectiveness of the distal side-to-side anastomosis (SSA) in CABG using internal mammary artery has been reported. The benefit of SSA comparing to ESA also has been disclosed by computing simulation. However, use of SSA by venous conduit for individual CABG has not been reported. In this study, we investigated feasibility of SSA. From January 2013 to October 2014, we conducted 114 CABGs. There were 92 venous distal anastomoses without sequential anastomotic site (61 SSA and 31 ESA). The anastomosis was evaluated before discharge and at 1 year after the procedure by angiography or multi-detector row computed tomographic coronary angiography. The median values for time to anastomosis were 13 min in the two group (p = 0.89). There was no revision of anastomosis in both groups. Additional stitches for hemostasis were required significantly less in SSA than ESA (18.0 vs 45.2 %, respectively, p fashion is easy to perform and maybe beneficial in blood flow pattern.

  1. Why fruits go to the dark side

    Science.gov (United States)

    Schaefer, H. Martin

    2011-11-01

    The colours of fleshy fruits are usually attributed to attract seed dispersers to the plant. A cursory look at the gaudy colours of fleshy fruits on offer in a local fruit stall gives the impression that plants use primarily bright colours to attract fruit consumer. This impression is misleading; many small fruits 'go to the dark side' and become dark purple or black when ripe. Intermingled in foliage, these colours, which are produced by anthocyanins, can be fairly inconspicuous and are thus not easily reconciled with a signalling function to attract seed dispersers. In this review I therefore discuss complementary hypotheses on the function and evolution of fruit colouration. First, I focus on the evidence that fruit colours indeed function as signals to attract seed dispersers. I then show that anthocyanins, the most prevalent fruit pigments, are important dietary antioxidants that can be selected by blackcaps ( Sylvia atricapilla) which are important avian seed dispersers of many European plants. Moreover, the consumption of anthocyanins increases the likelihood that blackcaps mount an immune response during immune challenges. As a next step, I review evidence that anthocyanins accumulate in fruit skin in response to abiotic factors, in particular high illumination coupled with low temperature favour the increase of anthocyanins. Finally, I show that anthocyanins can also be selected for by fruit antagonists, consumers that do not disperse seeds. In particular, high contents of anthocyanins strongly reduce fungal growth in fruit tissue. Taken together, there are various selective pressures which likely influence fruit colour evolution. Currently, the relative importance of each of these selective agents is unknown. There is consequently a need to develop a more encompassing framework on fruit colour evolution.

  2. The Dark Side of the Earth

    Science.gov (United States)

    Frankel, Henry

    1986-10-01

    Wood's The Dark Side of the Earth is another addition to the growing list of books on the recent revolution in the earth sciences. Wood rightly points out that any new book on the topic should break new ground. In the preface, he writes of himself and his book that he has benefited from previous accounts by saving himself research time, and that his book, unlike others, “attempts to tell one complete story of the study of the Earth, geologists, geophysicists, dreamers and all” (p. vi). Wood is ambitious, for his work covers much of 19th-century geology as well as the development, reception, rejection, and eventual acceptance of mobilist ideas. Before discussing the work of the German meteorologist and geophysicist Alfred L. Wegener, American glacial geomorphologist Frank Taylor, and several of their predecessors who proposed “mobilist” ideas, he manages to string together brief descriptions of the contributions of (among others) German mineralogist Abraham Gottlob Werner, British geologists James Hutten and John Playfair, British engineer William Smith, British geologist Charles Lyell, American geologists James Hall and James Dwight Dana, British volcanologist William Lowthian Green, American geologist Grove Karl Gilbert, French geologist Elie de Beaumont, British geologist and mathematician Osmond Fisher, American geologist Clarence Dutton, British mathematician and physicist Lord Kelvin, Austrian geologist Eduard Suess, French geologist Marcel Bertrand, and American geologist Thomas Chrowder Chamberlin. Moreover, Wood offers an interesting thesis about the revolution in the earth sciences. He claims that the real revolution was not the replacement of fixist views with the mobilist ones of sea floor spreading and plate tectonics, but rather the replacement of geology with the new discipline of the earth sciences in which geophysics and geochemistry play the central role.

  3. 发电侧如何促进需求侧管理%How to Improve Demand Side Management in Generation Side

    Institute of Scientific and Technical Information of China (English)

    劳德容

    2002-01-01

    Combining with the practice of DSM in China, the paper analyzes the role of engaging demand side management in generation side. Also it deeply studies how to promote demand side management in generation side, which rarelyinvolves in the published literature all over the world. Besides, it discovers the interactions of interdependence and competition between demand side managenent and generation side operation. Lastly it studies the example of demand side management in generation side in Shenzhen.

  4. Double Sided Si(Ge)/Sapphire/III-Nitride Hybrid Structure

    Science.gov (United States)

    Park, Yeonjoon (Inventor); Choi, Sang Hyouk (Inventor)

    2016-01-01

    One aspect of the present invention is a double sided hybrid crystal structure including a trigonal Sapphire wafer containing a (0001) C-plane and having front and rear sides. The Sapphire wafer is substantially transparent to light in the visible and infrared spectra, and also provides insulation with respect to electromagnetic radio frequency noise. A layer of crystalline Si material having a cubic diamond structure aligned with the cubic direction on the (0001) C-plane and strained as rhombohedron to thereby enable continuous integration of a selected (SiGe) device onto the rear side of the Sapphire wafer. The double sided hybrid crystal structure further includes an integrated III-Nitride crystalline layer on the front side of the Sapphire wafer that enables continuous integration of a selected III-Nitride device on the front side of the Sapphire wafer.

  5. Compressed sensing with side information on the feasible region

    CERN Document Server

    Rostami, Mohammad

    2013-01-01

    This book discusses compressive sensing in the presence of side information. Compressive sensing is an emerging technique for efficiently acquiring and reconstructing a signal. Interesting instances of Compressive Sensing (CS) can occur when, apart from sparsity, side information is available about the source signals. The side information can be about the source structure, distribution, etc. Such cases can be viewed as extensions of the classical CS. In these cases we are interested in incorporating the side information to either improve the quality of the source reconstruction or decrease the number of samples required for accurate reconstruction. In this book we assume availability of side information about the feasible region. The main applications investigated are image deblurring for optical imaging, 3D surface reconstruction, and reconstructing spatiotemporally correlated sources. The author shows that the side information can be used to improve the quality of the reconstruction compared to the classic...

  6. The study of CD side to side error in line/space pattern caused by post-exposure bake effect

    Science.gov (United States)

    Huang, Jin; Guo, Eric; Ge, Haiming; Lu, Max; Wu, Yijun; Tian, Mingjing; Yan, Shichuan; Wang, Ran

    2016-10-01

    In semiconductor manufacturing, as the design rule has decreased, the ITRS roadmap requires crucial tighter critical dimension (CD) control. CD uniformity is one of the necessary parameters to assure good performance and reliable functionality of any integrated circuit (IC) [1] [2], and towards the advanced technology nodes, it is a challenge to control CD uniformity well. The study of corresponding CD Uniformity by tuning Post-Exposure bake (PEB) and develop process has some significant progress[3], but CD side to side error happening to some line/space pattern are still found in practical application, and the error has approached to over the uniformity tolerance. After details analysis, even though use several developer types, the CD side to side error has not been found significant relationship to the developing. In addition, it is impossible to correct the CD side to side error by electron beam correction as such error does not appear in all Line/Space pattern masks. In this paper the root cause of CD side to side error is analyzed and the PEB module process are optimized as a main factor for improvement of CD side to side error.

  7. Intrinsic features of flow around two side-by-side square cylinders

    Science.gov (United States)

    Alam, Md. Mahbub; Zhou, Y.

    2013-08-01

    The wake of two side-by-side square cylinders is investigated in detail based on flow visualization at a Reynolds number (Re) of 300. The cylinder center-to-center spacing ratio T* (= T/W, W is the cylinder width) is varied from 1.0 to 5.0. The intrinsic features of the wake are explored, including the gap vortices, flow switch, stability, merging of two streets into one, etc. The qualitative information on these features is further complemented by the quantitative information extracted from hotwire data at Re = 4.7 × 104 using both spectral and cross-wavelet analyses. Four flow regimes are identified: (i) the single bluff body regime (T* 2.4). The gap flow is found to switch at two distinct time scales, referred to as macro and micro switches. Macro switch occurs at 1.2 gap flow is slim in width and biased for a long duration ranging from several vortex shedding periods in the wide street to several hours. Micro switch is observed at 2.1 gap flow is thick in width and switches at a frequency of twice the frequency of vortex shedding from the free-stream side of the cylinders. The two streets formed immediately behind the cylinders merge to a single street at a downstream location x_c^* that depends on T*. A larger T* corresponds to a larger x_c^*. Regime (iv) is characterized by two streets either inphased or antiphased. The antiphased streets persist longer than the inphased.

  8. Wake structures of two side by side spheres in a tripped boundary layer flow

    Science.gov (United States)

    Canli, Eyüb; Özgören, Muammer; Dogan, Sercan; Hilmi Aksoy, Muharrem; Akilli, Huseyin

    2014-03-01

    Two independent spheres were placed in a side by side arrangement and flow structure in the wake region of the spheres was investigated with a Particle Image Velocimetry (PIV) system when the spheres were in a boundary layer over a flat plate as a special case. Reynolds number was 5000 based on the sphere diameter which was 42.5 mm. Boundary layer was tripped 8mm away from the leading edge of the flat plate with a 5 mm trip wire. The thickness of the hydrodynamically developed boundary layer was determined as 63mm which was larger than the sphere diameter of D=42.5mm. Wake region of the spheres was examined from point of flow physics for the different sphere locations in the ranges of 0≤G/D ≤1.5 and 0≤S/D ≤1.5 where G and S were the distance between the spheres and the distance between the bottom point of the spheres and the flat plate surface, respectively. Depending on the different sphere locations, instantaneous and time averaged vorticity data, scalar values of time-averaged velocity components and their root mean square (rms) values and time averaged vorticity data are presented in the study for the evaluation of wake region of the spheres. It is demonstrated that the gap between the two spheres and the interaction between the gap and the boundary layer greatly affects flow pattern, especially when spheres are located near to the flat plate surface, i.e. S/D=0.1 for 0≤G/D ≤1.5. Different distances between the spheres resulted in various flow patterns as the spheres were approached to the flat plate. The distance S/D=0.1 for all gap values has the strongest effect on the wake structures. Beyond G/D=1.0, the sphere wakes tend to be similar to single sphere case. The instantaneous vorticity fields of the side by side arrangements comprised wavy structures in higher level comparing to an individual sphere case. The gap flow intensifies the occurrence of small scale eddies in the wake region. The submersion rate of the spheres actually determines the

  9. Wake structures of two side by side spheres in a tripped boundary layer flow

    Directory of Open Access Journals (Sweden)

    Canli Eyüb

    2014-03-01

    Full Text Available Two independent spheres were placed in a side by side arrangement and flow structure in the wake region of the spheres was investigated with a Particle Image Velocimetry (PIV system when the spheres were in a boundary layer over a flat plate as a special case. Reynolds number was 5000 based on the sphere diameter which was 42.5 mm. Boundary layer was tripped 8mm away from the leading edge of the flat plate with a 5 mm trip wire. The thickness of the hydrodynamically developed boundary layer was determined as 63mm which was larger than the sphere diameter of D=42.5mm. Wake region of the spheres was examined from point of flow physics for the different sphere locations in the ranges of 0≤G/D ≤1.5 and 0≤S/D ≤1.5 where G and S were the distance between the spheres and the distance between the bottom point of the spheres and the flat plate surface, respectively. Depending on the different sphere locations, instantaneous and time averaged vorticity data, scalar values of time-averaged velocity components and their root mean square (rms values and time averaged vorticity data are presented in the study for the evaluation of wake region of the spheres. It is demonstrated that the gap between the two spheres and the interaction between the gap and the boundary layer greatly affects flow pattern, especially when spheres are located near to the flat plate surface, i.e. S/D=0.1 for 0≤G/D ≤1.5. Different distances between the spheres resulted in various flow patterns as the spheres were approached to the flat plate. The distance S/D=0.1 for all gap values has the strongest effect on the wake structures. Beyond G/D=1.0, the sphere wakes tend to be similar to single sphere case. The instantaneous vorticity fields of the side by side arrangements comprised wavy structures in higher level comparing to an individual sphere case. The gap flow intensifies the occurrence of small scale eddies in the wake region. The submersion rate of the spheres

  10. On Cascade Source Coding with A Side Information "Vending Machine"

    CERN Document Server

    Ahmadi, Behzad; Choudhuri, Chiranjib; Mitra, Urbashi

    2012-01-01

    The model of a side information "vending machine" accounts for scenarios in which acquiring side information is costly and thus should be done efficiently. In this paper, the three-node cascade source coding problem is studied under the assumption that a side information vending machine is available either at the intermediate or at the end node. In both cases, a single-letter characterization of the available trade-offs among the rate, the distortions in the reconstructions at the intermediate and at the end node, and the cost in acquiring the side information are derived under given conditions.

  11. Review: Tales from Both Sides of the Brain

    Science.gov (United States)

    Landis, Theodor

    2015-01-01

    Our brain has two hemispheres that specialize in different jobs—the right side processes spatial and temporal information, and the left side controls speech and language. How these two sides come together to create one mind is explained by pioneering neuroscientist Michael Gazzaniga in his new book, Tales from Both Sides of the Brain : A Life in Neuroscience (Ecco/Harper Collins, 2015). Gazzaniga is director of the SAGE Center for the Study of the Mind at the University of California, Santa Barbara, and a Dana Alliance member. PMID:27408671

  12. "Source Coding With a Side Information ""Vending Machine"""

    OpenAIRE

    Weissman, Tsachy; Permuter, Haim H.

    2011-01-01

    We study source coding in the presence of side information, when the system can take actions that affect the availability, quality, or nature of the side information. We begin by extending the Wyner-Ziv problem of source coding with decoder side information to the case where the decoder is allowed to choose actions affecting the side information. We then consider the setting where actions are taken by the encoder, based on its observation of the source. Actions may have costs that are commens...

  13. Side-to-side growth discrepancies in children with hemiplegic cerebral palsy: association with function, activity and social participation

    Directory of Open Access Journals (Sweden)

    Marise Bueno Zonta

    2014-05-01

    Full Text Available Objective: Evaluate side-to-side discrepancies in children with hemiplegic cerebral palsy (HCP, and investigate associations of these discrepancies with patients’ age at initiation of physical therapy, motor and cognitive function, and degree of activities and social participation. Method: We obtained eight side-to-side measurements from 24 HCP children with mean age 49.3±5.2 months. Results: Early initiation of physical therapy was associated with lower discrepancy in hand length (p=0.037. Lower foot length discrepancy was associated with lower requirement for caregiver assistance in activities related to mobility. Increased side-to-side discrepancy was associated with reduced wrist extension and increased spasticity. Discrepancy played a larger role in children with hemineglect and in those with right involvement. Conclusion: Increased discrepancy in HCP children was associated with reduced degree of activity/social participation. These results suggest an association between functional use of the extremities and limb growth.

  14. Microfluidic conceived drug loaded Janus particles in side-by-side capillaries device.

    Science.gov (United States)

    Khan, Ikram Ullah; Serra, Christophe A; Anton, Nicolas; Li, Xiang; Akasov, Roman; Messaddeq, Nadia; Kraus, Isabelle; Vandamme, Thierry F

    2014-10-01

    A side-by-side capillaries microfluidic device was developed to fabricate drug loaded poly(acrylamide)/poly(methyl acrylate) Janus particles in the range of 59-240 μm by UV-assisted free radical polymerization. This system was characterized in terms of continuous and dispersed phases flow rates (Qc/Qd), monomer composition of the two compartments, surfactant nature and concentration, outlet tube diameter and UV intensity. These factors were adequately controlled to get different particle shapes ranging from core-shell to bi-compartmental particles. For the latter, a low surfactant concentration (0.75 wt.%) was necessary when the two dispersed phases were pumped at equal flow rate, while at high surfactant concentration, dispersed phases flow rates have to be changed. FTIR analysis suggested complete polymerization of monomers and cytotoxicity test showed these particles were biocompatible having LD 50 of 9 mg/mL. Both ketoprofen and sodium fluorescein were released in sustained release manner at pH 6.8 by following a diffusion type release mechanism. Drug release was faster for bigger particles and found to result from the irregular distribution of the two phases and indentation on bigger particles as revealed by SEM analysis. In comparison, sodium fluorescein release was slower which was attributed to low encapsulation but could be modified by decreasing crosslinker concentration.

  15. Order, Disorder and Stretching of a Smectic Elastomer with ‘side-on’ Mesogenic Side Groups

    Energy Technology Data Exchange (ETDEWEB)

    de Jeu, W.; Komp, A; Obraztsov, E; Ostrovskii, B; Finkelmann, H

    2009-01-01

    We report an X-ray study of the order in a 'side-on' smectic-A elastomer in which both the polymer backbone and the mesogenic side groups are, on average, parallel to the smectic layer normal. The present system shows in all phases locally correlated structures as evidenced by systematic diffuse scattering at small angles, attributed to the fluorinated end groups of the mesogens. The elastomer shows order of the smectic layers over a limited range in spite of the relatively low crosslink concentration (4%). Upon stretching along the layer normal we find a linear increase of the smectic layer period for small loading (elastic regime). These changes parallel the stress variation for the elastic part of the macroscopic stress-strain curve and saturate at larger strains. The attendant increase in the width of the X-ray peaks indicates a decrease of the average domain dimensions. In the plastic regime no distortion of the smectic monodomain structure or layer rotation is observed. Instead the stress is relieved by 'melting' of the layer structure giving rise to a nematic-like state with short-range layer correlations: at the final stage about four smectic layers.

  16. Study of fluid resonance between two side-by-side floating barges

    Institute of Scientific and Technical Information of China (English)

    李欣; 徐亮瑜; 杨建民

    2016-01-01

    The hydrodynamic interaction between two vessels in a side-by-side configuration attracted research attentions in recent years. However, because the conventional potential flow theory does not consider the fluid viscosity, in the hydrodynamic results, the wave elevations were overestimated in the narrow gap under resonance conditions. To overcome this limitation and investigate the complex fluid flow around multiple bodies in detail, this study examines the fluid resonance between two identical floating barges using a viscous flow analysis program FLOW-3D. The volume of fluid method is implemented for tracking the free surface, and a porous media model is used near the outflow boundary to enhance the wave absorption. A three-dimensional numerical wave basin is established and validated by comparison with the waves generated using theoretical values. On this basis, a computational fluid dynamics (CFD) simulation of the two barges in a resonance wave period is performed, and the wave elevations, the fluid flow around the barges, and the motions of the barges are discussed. The numerical simulation is verified by comparison with results of corresponding experimental data.

  17. FLOW PAST TWO ROTATING CIRCULAR CYLINDERS IN A SIDE-BY-SIDE ARRANGEMENT

    Institute of Scientific and Technical Information of China (English)

    GUO Xiao-hui; LIN Jian-zhong; TU Cheng-xu; WANG Hao-li

    2009-01-01

    Measurements were performed using Particle Image Velocimetry (PIV) to analyze the modification of flow by the combined effects of the rotation and the Reynolds number on the flow past two rotating circular cylinders in a side-by-side-arrangement at a range of , (α is the rotational speed) at one gap spacing of (T and d are the distance between the centers of two cylinders and the cylinder diameter, respectively). A new Immersed-Lattice Boltzmann Method (ILBM) scheme was used to study the effect of the gap spacing on the flow. The results show that the vortex shedding is suppressed as rotational speed increases. The flow reaches a steady state when the vortex shedding for both cylinders is completely suppressed at critical rotational speed. As the rotational speed further increases, the separation phenomenon in the boundary layers disappears at the attachment rotational speed. The critical rotational speed and attachment rotational speed become small as Reynolds number increases. The absolute rotational speed of cylinders should be large at same critical rotational speed and attachment rotational speed in the case of large Reynolds number. The gap spacing has an important role in changing the pattern of vortex shedding. It is very different in the mechanism of vortex shedding suppression for the flows around two rotating cylinders and single rotating cylinder.

  18. Modality-specific communication enabling gait synchronization during over-ground side-by-side walking.

    Science.gov (United States)

    Zivotofsky, Ari Z; Gruendlinger, Leor; Hausdorff, Jeffrey M

    2012-10-01

    An attentive observer will notice that unintentional synchronization of gait between two walkers on the street seems to occur frequently. Nonetheless, the rate of occurrence and motor-sensory mechanisms underlying this phase-locking of gait have only recently begun to be investigated. Previous studies have either been qualitative or carried out under non-natural conditions, e.g., treadmill walking. The present study quantitatively examined the potential sensory mechanisms that contribute to the gait synchronization that occurs when two people walk side by side along a straight, over-ground, pathway. Fourteen pairs of subjects walked 70 m under five conditions that manipulated the available sensory feedback. The modalities studied were visual, auditory, and tactile. Movement was quantified using a trunk-mounted tri-axial accelerometer. A gait synchronization index (GSI) was calculated to quantify the phase synchronization of the gait rhythms. Overall, 36% of the walks exhibited synchrony. Tactile and auditory feedback showed the greatest ability to synchronize, while visual feedback was the least effective. The results show that gait synchronization during natural walking is common, quantifiable, and has modality-specific properties.

  19. Numerical Study on Interaction Between Two Bubbles Rising Side by Side in CMC Solution

    Institute of Scientific and Technical Information of China (English)

    FAN Wenyuan; YIN Xiaohong

    2013-01-01

    A numerical simulation was performed to investigate the interaction of two bubbles rising side by side in shear-thinning fluid using volume of fluid (VOF) method coupled with continuous surface force (CSF) method.By considering rheological characteristics of fluid,this approach was able to accurately capture the deformation of bubble interface,and validated by comparing with the experimental results.The rising of bubble pairs with different configurations,including horizontal alignment and oblique alignment,was simulated by the method.The influences of the bubble initial distance and the bubble alignment were studied by analyzing the bubble deformation,rising paths and flow fields surrounding bubbles.The results indicate that within certain initial bubble spacing of S* =3.3(S* =SI/D,SI initial distance between bubbles,and D bubble diameter),the dynamic interaction between two bubbles aligned horizontally shows repulsive effect that decreases with the increase of initial bubble spacing,but weakens to certain degree by the shear-thinning properties of fluid.However,the interaction between two bubbles aligned obliquely presents a repulsive effect for the small angle involved but an attractive impact for the large one,which is yet strengthened by the rheological characteristics of fluid.

  20. Propulsive performance of unsteady tandem hydrofoils in a side-by-side configuration

    Science.gov (United States)

    Dewey, Peter A.; Quinn, Daniel B.; Boschitsch, Birgitt M.; Smits, Alexander J.

    2014-04-01

    Experimental and analytical results are presented on two identical bio-inspired hydrofoils oscillating in a side-by-side configuration. The time-averaged thrust production and power input to the fluid are found to depend on both the oscillation phase differential and the transverse spacing between the foils. For in-phase oscillations, the foils exhibit an enhanced propulsive efficiency at the cost of a reduction in thrust. For out-of-phase oscillations, the foils exhibit enhanced thrust with no observable change in the propulsive efficiency. For oscillations at intermediate phase differentials, one of the foils experiences a thrust and efficiency enhancement while the other experiences a reduction in thrust and efficiency. Flow visualizations reveal how the wake interactions lead to the variations in propulsive performance. Vortices shed into the wake from the tandem foils form vortex pairs rather than vortex streets. For in-phase oscillation, the vortex pairs induce a momentum jet that angles towards the centerplane between the foils, while out-of-phase oscillations produce vortex pairs that angle away from the centerplane between the foils.

  1. Interface Oscillation in the Side-by-Side (SBS) Tape Casting of Functionally Graded Ceramics (FGCs)

    Science.gov (United States)

    Jabbari, Masoud; Bulatova, Regina; Hattel, Jesper; Bahl, Christian

    2012-11-01

    Room temperature magnetic refrigeration is a new highly efficient and environmentally protective technology. Although it has not been maturely developed, it shows great applicable prosperity and seems to be a potential substitute for the traditional vapor compression technology. Tape Casting is a common process in producing multilayer ceramics, which now is used for producing side-by-side (SBS) functionally graded ceramics (FGCs). These FGCs are mostly used in the magnetic refrigeration sectors due to the varying composition of the magnetocaloric materials so that the magnetic transition temperature of the magnetic regenerator varies along the paths. The main goal of this research is to study the multiple material flow in SBS tape casting and analyze its influence on the interface between the stripes. The materials used for the experimental part are La0 . 85 Sr0 . 15 MnO3 and Ce0 . 9 Gd0 . 1O2 ceramic slurries. The rheological behavior of the slurries are extracted from experiments and used in the ANSYS FLUENT commercial code to develop a fluid flow model for the non-Newtonian ceramic slurries and evaluate the interface oscillation between the stripes in SBS tape casting. The Numerical results show reasonable agreement with corresponding experimental results.

  2. Side-by-side ANFIS as a useful tool for estimating correlated thermophysical properties

    Science.gov (United States)

    Grieu, Stéphane; Faugeroux, Olivier; Traoré, Adama; Claudet, Bernard; Bodnar, Jean-Luc

    2015-12-01

    In the present paper, an artificial intelligence-based approach dealing with the estimation of correlated thermophysical properties is designed and evaluated. This new and "intelligent" approach makes use of photothermal responses obtained when homogeneous materials are subjected to a light flux. Commonly, gradient-based algorithms are used as parameter estimation techniques. Unfortunately, such algorithms show instabilities leading to non-convergence in case of correlated properties to be estimated from a rebuilt impulse response. So, the main objective of the present work was to simultaneously estimate both the thermal diffusivity and conductivity of homogeneous materials, from front-face or rear-face photothermal responses to pseudo random binary signals. To this end, we used side-by-side neuro-fuzzy systems (adaptive network-based fuzzy inference systems) trained with a hybrid algorithm. We focused on the impact on generalization of both the examples used during training and the fuzzification process. In addition, computation time was a key point to consider. That is why the developed algorithm is computationally tractable and allows both the thermal diffusivity and conductivity of homogeneous materials to be simultaneously estimated with very good accuracy (the generalization error ranges between 4.6% and 6.2%).

  3. SLAR = USGS Side Looking Airborne Radar Mosaics: 1981 - 1990

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — The Side-Looking Airborne Radar (SLAR) is an image-producing system that derives its name from the fact that the radar beam is transmitted from the side of the...

  4. Role of bicarbonate at the acceptor side of photosystem II

    NARCIS (Netherlands)

    Rensen, van J.J.S.

    2002-01-01

    Besides being the substrate for the carboxylation reaction of photosynthesis, CO2 (bicarbonate) is required for the activity of Photosystem II (water plastoquinone oxido-reductase). It plays a role on the electron donor side as well as the electron acceptor side. In this contribution, attention will

  5. Side Effects of Chemotherapy and Radiation (For Parents)

    Science.gov (United States)

    ... 1- to 2-Year-Old Side Effects of Chemotherapy and Radiation KidsHealth > For Parents > Side Effects of Chemotherapy and Radiation Print A A A What's in ... and can no longer do their jobs efficiently. Chemotherapy (or "chemo") and radiation , the two most common ...

  6. The relationship between rational drug design and drug side effects.

    Science.gov (United States)

    Wang, Juan; Li, Zhi-xin; Qiu, Cheng-xiang; Wang, Dong; Cui, Qing-hua

    2012-05-01

    Previous analysis of systems pharmacology has revealed a tendency of rational drug design in the pharmaceutical industry. The targets of new drugs tend to be close with the corresponding disease genes in the biological networks. However, it remains unclear whether the rational drug design introduces disadvantages, i.e. side effects. Therefore, it is important to dissect the relationship between rational drug design and drug side effects. Based on a recently released drug side effect database, SIDER, here we analyzed the relationship between drug side effects and the rational drug design. We revealed that the incidence drug side effect is significantly associated with the network distance of drug targets and diseases genes. Drugs with the distances of three or four have the smallest incidence of side effects, whereas drugs with the distances of more than four or smaller than three show significantly greater incidence of side effects. Furthermore, protein drugs and small molecule drugs show significant differences. Drugs hitting membrane targets and drugs hitting cytoplasm targets also show differences. Failure drugs because of severe side effects show smaller network distances than approved drugs. These results suggest that researchers should be prudent on rationalizing the drug design. Too small distances between drug targets and diseases genes may not always be advantageous for rational design for drug discovery.

  7. Organizational mediators siding with or against the powerful party

    NARCIS (Netherlands)

    Laskewitz, P; Van de Vliert, E; De Dreu, C K W

    1994-01-01

    Instead of being impartial, a mediator may side with one party as a function of the disputants' power differences, the mediator's legitimacy judgments, or the disputants' capacity to sanction the mediator. According to the power balancing theory, a mediator sides with the party that has a power disa

  8. Rare combination of dextrocardia with right-sided Poland syndrome.

    Science.gov (United States)

    Lee, Seung Hyun; Kim, Jae Bum; Park, Nam Hee; Keum, Dong Yoon; Kim, Yeo Hyang

    2012-10-01

    The combination of right-sided Poland syndrome and dextrocardia is rare. To our knowledge, reports regarding this subject are lacking in the published literature to date. Previous reports suggested that dextrocardia may be part of the left sided Poland syndrome. We report and discuss this rare combination.

  9. Weakening of a Polyethylene Chain by Methyl Side Groups

    NARCIS (Netherlands)

    Hageman, J.C.L.; Wijs, G.A. de; Groot, R.A. de; Meier, Robert J.

    2003-01-01

    The effect of methyl side groups on the strength of a single polyethylene chain is calculated with Density Functional Theory. Using transition state theory, the scission rate is calculated as function of stress for bonds next to a methyl side group. The increase in the scission rate due to the prese

  10. Effects and Side Effects of Flemish School Inspection

    Science.gov (United States)

    Penninckx, Maarten; Vanhoof, Jan; De Maeyer, Sven; Van Petegem, Peter

    2016-01-01

    Despite the increased importance of school inspection in recent years, the current knowledge base does not provide a clear view on the effects and side effects of being inspected. More evidence is needed in more diverse educational contexts. This article responds to this need with a quantitative study on the effects and side effects of school…

  11. Side effects of azathioprine in patients with Crohn's disease.

    NARCIS (Netherlands)

    Jong, Dirk de; Goullet, M.; Naber, A.H.J.

    2004-01-01

    OBJECTIVE: In clinical trials 0-15% of patients discontinued azathioprine due to side effects. The aim of this study was to assess the rate of side effects leading to discontinuation of azathioprine and to determine predictive factors for discontinuation. DESIGN: A retrospective cohort analysis of c

  12. The incidence of side effects after laser hair removal

    Science.gov (United States)

    Lanigan, Sean W.

    2004-09-01

    Despite the widespread use of lasers for hair removal there is little data published on the incidence of side effects from this treatment. We aimed to generate data on a large number of patients receiving laser hair removal to obtain an accurate assessment of the incidence and type of side effects resulting from treatment. A multicentre prospective study of patients attending for laser hair removal was conducted to determine incidence of side effects in relation to skin type and laser(s) used. Laser hair removal is associated with a low incidence of side effects which are self-limiting in the majority of cases. Highest incidence of side effects was seen in darker skinned patients treated with the long pulsed ruby laser. Laser hair removal is inherently safe. For darker Fitzpatrick skin types the long pulsed Nd:YAG laser is preferred to the ruby laser.

  13. Status and Results from DarkSide-50

    CERN Document Server

    Fan, Alden

    2015-01-01

    DarkSide-50 is the first physics detector of the DarkSide dark matter search program. The detector features a dual-phase underground-argon Time Projection Chamber (TPC) of 50 kg active mass surrounded by an organic liquid-scintillator neutron veto (30 tons) and a water-Cherenkov muon detector (1000 tons). The TPC is currently fully shielded and operating underground at Gran Sasso National Laboratory. A first run of 1422 kg-day exposure with atmospheric argon represents the most sensitive dark matter search using a liquid argon target. The TPC is now filled with underground argon, greatly reduced in 39Ar, and DarkSide-50 is in its final configuration for an extended dark matter search. Overviews of the design, performance, and results obtained so far with DarkSide-50 will be presented, along with future prospects for the DarkSide program.

  14. Ecological engineering of bioaugmentation from side-stream nitrification.

    Science.gov (United States)

    Smith, R C; Saikaly, P E; Zhang, K; Thomatos, S; Oerther, D B

    2008-01-01

    Wastewater treatment relies on careful integration of environmental engineering with microbial ecology. This would seem to be particularly the case when attempting to enhance survivability of organisms introduced from outside the main-stream reactor, i.e. bioaugmentation. Molecular biology tools were utilised in this study to assist in understanding the mechanisms of successful bioaugmentation. Molecular fingerprinting showed that side-stream reactor configuration strongly influenced ammonia-oxidising bacteria (AOB) community structure. In both lab-scale and full-scale systems, AOB communities in the side-stream and main-stream were very similar. The experimental systems revealed that a PFR side-stream produced greater diversity of AOB than a CSTR side-stream in a PFR main-stream system, whereas the full-scale side-stream resulted in essentially an AOB monoculture. Phylogenetic analysis revealed less diversity than molecular fingerprinting perhaps due to biases in the cloning/transformation procedure.

  15. Collusion in Markets with Imperfect Price Information on Both Sides

    DEFF Research Database (Denmark)

    Schultz, Christian

    The paper considers tacit collusion in markets which are not fully transparent on both sides. Consumers only detect prices with some probability before deciding which firm to purchase from, and each firm only detects the other firm's price with some probability. Increasing transparency on the pro......The paper considers tacit collusion in markets which are not fully transparent on both sides. Consumers only detect prices with some probability before deciding which firm to purchase from, and each firm only detects the other firm's price with some probability. Increasing transparency...... on the producer side facilitates collusion, while increasing transparency on the consumer side makes collusion more difficult. Conditions are given under which increases in a common factor, affecting transparency positively on both sides, are pro-competitive. With two standard information technologies, this is so...

  16. A side effect resource to capture phenotypic effects of drugs

    DEFF Research Database (Denmark)

    Kuhn, Michael; Campillos, Monica; Letunic, Ivica

    2010-01-01

    The molecular understanding of phenotypes caused by drugs in humans is essential for elucidating mechanisms of action and for developing personalized medicines. Side effects of drugs (also known as adverse drug reactions) are an important source of human phenotypic information, but so far research...... on this topic has been hampered by insufficient accessibility of data. Consequently, we have developed a public, computer-readable side effect resource (SIDER) that connects 888 drugs to 1450 side effect terms. It contains information on frequency in patients for one-third of the drug-side effect pairs. For 199...... drugs, the side effect frequency of placebo administration could also be extracted. We illustrate the potential of SIDER with a number of analyses. The resource is freely available for academic research at http://sideeffects.embl.de....

  17. The nocebo effect: patient expectations and medication side effects.

    Science.gov (United States)

    Faasse, Kate; Petrie, Keith J

    2013-09-01

    Expectation of treatment side effects is consistently linked with those symptoms being realised. Patient expectations, including those generated by the informed consent process, can have a large influence on the side effects that patients feel after starting a new medical treatment. Such symptoms may be the result of the nocebo effect, whereby the expectation of side effects leads to them being experienced. Side effects may also be due to the misattribution of pre-existing or unrelated symptoms to the new medication. Medical professionals' own negative beliefs about a treatment, especially generic drugs, may further enhance patients' expectations of adverse effects. The news media may also influence expectations, particularly when media attention is directed towards a health or medication scare. This field of research has ethical and clinical implications for both medical professionals and the news media with respect to the level and type of information about treatment side effects that is provided to patients or members of the public.

  18. Research Needs: Glass Solar Reflectance and Vinyl Siding

    Energy Technology Data Exchange (ETDEWEB)

    Hart, Robert; Curcija, Charlie; Arasteh, Dariush; Goudey, Howdy; Kohler, Christian; Selkowitz, Stephen

    2011-07-07

    The subject of glass solar reflectance and its contribution to permanent vinyl siding distortion has not been extensively studied, and some phenomena are not yet well understood. This white paper presents what is known regarding the issue and identifies where more research is needed. Three primary topics are discussed: environmental factors that control the transfer of heat to and from the siding surface; vinyl siding properties that may affect heat build-up and permanent distortion; and factors that determine the properties of reflected solar radiation from glass surfaces, including insulating window glass. Further research is needed to fully characterize the conditions associated with siding distortion, the scope of the problem, physical properties of vinyl siding, insulating window glass reflection characteristics, and possible mitigation or prevention strategies.

  19. Are peripheral opioid antagonists the solution to opioid side effects?

    LENUS (Irish Health Repository)

    Bates, John J

    2012-02-03

    Opioid medication is the mainstay of therapy for severe acute and chronic pain. Unfortunately, the side effects of these medications can affect patient comfort and safety, thus limiting their proven therapeutic potential. Whereas the main analgesic effects of opioids are centrally mediated, many of the common side effects are mediated via peripheral receptors. Novel peripheral opioid antagonists have been recently introduced that can block the peripheral actions of opioids without affecting centrally mediated analgesia. We review the clinical and experimental evidence of their efficacy in ameliorating opioid side effects and consider what further information might be useful in defining their role. IMPLICATIONS: The major analgesic effects of opioid medication are mediated within the brain and spinal cord. Many of the side effects of opioids are caused by activation of receptors outside these areas. Recently developed peripherally restricted opioid antagonists have the ability to block many opioid side effects without affecting analgesia.

  20. Analysis of Kirk effect of an innovated high side Side-Isolated N-LDMOS device

    Directory of Open Access Journals (Sweden)

    Lai Ciou Jhong

    2016-01-01

    Full Text Available An ESOA of LDMOS device is very critical for power device performance. Kirk effect is the one of the major problem which leads to poor ESOA performance. The cause of the problem mainly due to the high beta value of parasitic NPN transistor in the p-body. In this study, we proposed a new 3D high side Side–Isolated N-Channel LDMOS which we have obtained not only benchmark Ron and breakdown performance, but also better ESOA without Kirk effect. We have compared the analysis of Kirk effect between the new device and the conventional N–LDMOS structure with LATID technique for the formation of the p–body of both device structures.

  1. THE DILEMMA OF DEMAND SIDE POLICIES VERSUS SUPPLY SIDE POLICIES FOR RELAUNCHING CAPITALIST ECONOMIES

    Directory of Open Access Journals (Sweden)

    PETRE PRISECARU

    2014-11-01

    Full Text Available The first important economic recession in this century started in USA with the burst of real estate bubble followed by the bankruptcy of some investment and commercial banks and the collapse of capital market. The financial-banking crisis spilt over the world economy and caused the second deepest economic recession in the last 80 years. The financial crisis has badly affected almost all market economies and was the result of a combination between market failures and mistakes made in macroeconomic policies. In the financial sector there was not enough regulation and supervision of corporate governance while in goods industry the pressure of over-regulation led to higher factor costs and supply contraction. The direct result of supply side policies and particularly of monetarist instruments is seen now clearly in the USA: large deficits, huge debts, reduced savings, heavy dependence on foreign money (capital and resources, relatively low domestic output and supply.

  2. Immediate Small Side Branch Occlusion after Percutaneous Coronary Intervention

    Directory of Open Access Journals (Sweden)

    Mohammad Ali Ostovan

    2007-09-01

    Full Text Available Background: Small side branches, albeit less important than their larger counterparts, have not yet received due attention in the literature. Nor has there ever been a comparison between drug-eluting stents and bare metal stents apropos side branch occlusion. The aim of this study was to compare the patency of small (≥0.5 and ≤1.5 mm in diameter side branches with respect to bare metal vs. drug-eluting stents immediately after their deployment.Methods: This prospective bi-center study, conducted between June 2005 and January 2007, enrolled 82 patients treated with ≥1 of two stents (TAXUSTM LiberteTM or LiberteTM. Side branches ≥0.5 and <1.5 mm in diameter arising from the main vessel at the lesion site were evaluated. Results: Thirty-eight patients were treated with 42 LiberteTM stents (58 side branches and forty-four patients with 50 TAXUSTM LiberteTM (102 side branches. The rate of small side branch occlusion was 35.3% (36 in the TAXUSTM LiberteTM group compared to 29.31% (15 in the LiberteTM group (P-value= 0.7. The presence of type 1 side branch morphology (Lefevre classification was the most powerful predictor of small side branch occlusion (P-value=0.03. Conclusion: This study shows that drug-eluting stents are not inferior to bare metal stents as regards small side branch occlusion during coronary stenting

  3. Criticality of flow transition behind two side-by-side elliptic cylinders

    Science.gov (United States)

    Peng, Y. F.; Sau, Amalendu; Hwang, Robert R.; Yang, W. C.; Hsieh, Chih-Min

    2012-03-01

    In this study, near-critical bifurcations of low Reynolds number (Re) flows past a pair of elliptic cylinders in the side-by-side arrangement are numerically investigated, and onsets of several distinct transition scenarios are addressed. A nested Cartesian-grid formulation, in combination with an effective immersed boundary method and a two-step fractional-step procedure, has been adopted to simulate the flows. The transition scenarios associated with various periodic, quasi-periodic, and biased flows, their bifurcation characteristics, corresponding critical Reynolds numbers, and phase-portraits are exploited to better understand the governing physics. From the global point of view, there appear variety of flow patterns within the investigated parameter space, 40 ⩽ Re ⩽ 300, 0.2 ⩽ G ⩽ 3.0 (G being the gap-ratio of the cylinders), and 1.5 ⩽ A ⩽ 3 (A is the cylinder aspect-ratio), which include, symmetric vortex shedding mode, semi-single/twin vortex street formations, asymmetric/deflected flows, stationary/biased flip-flopped-type vortex shedding, weakly-chaotic flows, and in-phase/anti-phase vortex synchronizations. We numerically present these flows by tuning Re quasi-stationary, and provide a broader understanding of the entire transition process. A comprehensive analysis of effects of Reynolds number, the gap-ratio, and the angle of incidence on different flow-induced forces on the cylinders is included in this regard. On the other hand, our simulated wakes with various non-zero incidence-angles are found to reveal a rich variety of instability induced weakly synchronized physical evolution characteristics, which remained virtually unexplored.

  4. A nationwide Danish cohort study challenging the categorisation into right-sided and left-sided colon cancer

    DEFF Research Database (Denmark)

    Jess, Per; Hansen, Iben Onsberg; Gamborg, Michael;

    2013-01-01

    The categorisation of colon cancer (CC) into right-sided (RCC) and left-sided (LCC) disease may not capture more subtle variances in aetiology and prognosis. In a nationwide study, we investigated differences in clinical characteristics and survival of RCC versus LCC and of the complete range of CC...

  5. Supply-side and demand-side cost sharing in deregulated social health insurance: which is more effective?

    Science.gov (United States)

    Trottmann, Maria; Zweifel, Peter; Beck, Konstantin

    2012-01-01

    Microeconomic theory predicts that if patients are fully insured and providers are paid fee-for-service, utilization of medical services exceeds the efficient level ('moral hazard effect'). In Switzerland, both demand-side and supply-side cost sharing have been introduced to mitigate this problem. Analyzing a panel dataset of about 160,000 adults, we find both types of cost sharing to be effective in curtailing the use of medical services. However, when moral hazard mitigation is traded off against risk selection, the minimum-deductible, supply-side cost sharing option ranks first, followed by the medium-deductible demand-side alternative, making the supply-side option somewhat more effective.

  6. Rational Design of Coordination Polymers with Flexible Oxyethylene Side Chains

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Eun Young; Gao, Chunji; Lee, Suck Hyun; Kwon, O Pil [Ajou University, Suwon (Korea, Republic of)

    2012-04-15

    We rationally designed and synthesized metallopolymers with organic 1,4-benzenedicarboxylic acid (BDC) linkers with different lengths of oxyethylene side chains in order to examine the influence of side chains on the coordination characteristics. While in a previous report the BDC linkers with alkyl side chains were found to form three-dimensional (3D) isoreticular metal-organic framework (IRMOF) structures or one-dimensional (1D) coordination polymeric structures with short -O(CH{sub 2}){sub 6}CH{sub 3} or long -O(CH{sub 2}){sub 9}CH{sub 3} side chains, respectively, new BDC linkers with oxyethylene side chains of the same lengths, -(OCH{sub 2}CH{sub 2}){sub 2}CH{sub 3} and -(OCH{sub 2}CH{sub 2}){sub 3}CH{sub 3}, form only 3D IRMOF structures. This result is attributed to the higher flexibility and smaller volume of oxyethylene side chains compared to alkyl side chains

  7. A gecko-inspired double-sided adhesive.

    Science.gov (United States)

    Wang, Zhengzhi; Gu, Ping; Wu, Xiaoping

    2013-12-21

    Geckos' outstanding abilities to adhere to various surfaces are widely credited to the large actual contact areas of the fibrillar and hierarchical structures on their feet. These special features regulate the essential structural compliance for every attachment and thus provide robust yet reversible adhesions. Inspired by gecko's feet and our commonly used double-faced tape, we have successfully fabricated a gecko-inspired double-sided dry adhesive by using porous anodic alumina template assisted nano-wetting on a stiff polymer. It was determined that the obtained 2-sided structure showed largely decreased effective stiffness compared with its 1-sided counterpart, which favored better compliance and interfacial integrity. We also demonstrated that the repeatable double-sided adhesive improved the macroscopic normal and shear adhesion capacities over the widely-studied 1-side structure by ~50% and ~85%, respectively. By using the synthetic double-sided adhesive, the usage of traditional pressure-sensitive/chemical adhesives could be well avoided. Besides, the double-sided nanostructures showed great potential in finding new interesting properties and practical applications for the synthetic dry adhesives.

  8. Reported Sildenafil Side Effects in Pediatric Pulmonary Hypertension Patients

    Directory of Open Access Journals (Sweden)

    Stephanie Leigh Siehr

    2015-03-01

    Full Text Available Background: Sildenafil, a phosphodiestase type 5 inhibitor, was approved in 2005 for the treatment of pulmonary arterial hypertension (PAH in adults, and is commonly used off-label for pediatric patients. Little is known, however, about sildenafil’s side effects in this population.Methods: Single institution, longitudinal survey-based study performed in an outpatient pediatric cardiology clinic. Pediatric patients on sildenafil (alone or in combination with other PH therapies completed questionnaires regarding frequency of vascular, gastrointestinal, neurologic and hematologic side effects. Results: Between January 2011 and May 2014, 66 pediatric patients with PH on sildenafil filled out 214 surveys, 32 patients (96 surveys on monotherapy, and 43 patients (118 surveys on sildenafil plus an endothelin receptor antagonist (bosentan or ambrisentan and/or a prostacyclin (epoprostenol or treprostinil. Overall, 30% of respondents identified at least one side effect. For all patients on sildenafil, incidence of side effects by system was 37% gastrointestinal, 35% vascular and 22% neurologic. For patients on sildenafil monotherapy, incidence of side effects by system was 24% gastrointestinal, 21% vascular and 18% neurologic compared to patients on combination therapy who reported an incidence of 48% gastrointestinal, 45% vascular and 25% neurologic.Conclusion: Incidence of vascular, gastrointestinal and neurologic side effect in pediatric patients on sildenafil therapy for pulmonary arterial hypertension was 30%. Side effects were more common in patients on combination therapy with an endothelin receptor antagonist and/or prostacyclin than in patients on sildenafil monotherapy.

  9. Coding with Side Information for Radiation-Tolerant Memory Devices

    Science.gov (United States)

    Hwang, E.; Jeon, S.; Negi, R.; Vijaya Kumar, B. V. K.; Cheng, M. K.

    2011-11-01

    Memory devices aboard spacecraft experience radiation-induced errors either in the form of temporary upsets (soft errors) or permanent defects (hard or stuck-at errors). Error-correcting codes (ECCs) are used to recover memory content from errors where defective cells are either regarded as erasures by the decoder or entire blocks containing defective cells are marked as unusable. In this article, alternative coding schemes are investigated for memory devices in space, where the encoder is provided with the locations of the defective cells, denoted by side information. This coding approach has the potential to improve the overall storage capacity of memory devices, since the information theoretic capacity of a channel where side information is only available at the encoder is the same as the capacity where side information is available at both the encoder and decoder. Spacecraft memory controllers typically scrub memory devices periodically for errors. Partial side information can be obtained during this scrubbing process by comparing the ECC decoder output with its input and thereby avoid the need for additional cell tests or storage overhead. In between scrubbings, the encoder can use this partial side information to account for permanent defects to improve reliability or to increase the storage capacity of onboard memory devices. In order to achieve performance gains for practical memory systems, several coding schemes that adaptively incorporate the codeword with the known side information are proposed in this article. The proposed coding schemes are evaluated by numerical simulations on a memory channel model characterized by soft and hard errors. Simulation results show that while coding with complete side information at the encoder offers the most performance gain compared to when coding without side information is used, coding with partial side information can close the gap between the optimal and current approach without incurring much additional overhead

  10. Left-sided gall bladder: Report of two cases

    Directory of Open Access Journals (Sweden)

    Chrungoo R

    2007-01-01

    Full Text Available Left-sided gall bladder without situs inversus viscerum is a rare albeit recognized clinical entity. We report our experience of two cases of left-sided gall bladder in two women aged 36 and 48 who underwent laparoscopic cholecystectomy for chronic calculous cholecystitis. Left-sided gall bladder may provide an unusual surprise to the surgeons during laparoscopy as routine pre-operative studies may not always detect the anomaly. Awareness of the unpredictable confluence of the cystic duct into the common bile duct (CBD and selective use of intraoperative cholangiography aid in the safe laparoscopic management of this unusual entity.

  11. In vivo assessment of antiretroviral therapy-associated side effects

    Directory of Open Access Journals (Sweden)

    Eduardo Milton Ramos-Sanchez

    2014-07-01

    Full Text Available Antiretroviral therapy has been associated with side effects, either from the drug itself or in conjunction with the effects of human immunodeficiency virus infection. Here, we evaluated the side effects of the protease inhibitor (PI indinavir in hamsters consuming a normal or high-fat diet. Indinavir treatment increased the hamster death rate and resulted in an increase in triglyceride, cholesterol and glucose serum levels and a reduction in anti-oxLDL auto-antibodies. The treatment led to histopathological alterations of the kidney and the heart. These results suggest that hamsters are an interesting model for the study of the side effects of antiretroviral drugs, such as PIs.

  12. Side Effects and Complications of Dental Materials on Oral Cavity

    Directory of Open Access Journals (Sweden)

    Z. Atai

    2007-01-01

    Full Text Available Development of dental materials has had a great impact on the modern dentistry. The materials ranging from polymers to metals have different applications in dentistry. Besides their important role in healing or improving the function of oral tissues, the materials may show side effects which may, in some cases, lead to severe lesions. In this review the side effects have been summarized considering a new classification for dental materials according to the duration of their applications as temporary or permanent materials. The side effects of the materials are then discussed based on clinical and cellular views.

  13. Double Sided Watermark Embedding and Detection with Perceptual Analysis

    CERN Document Server

    Zhong, Jidong

    2007-01-01

    In our previous work, we introduced a double-sided technique that utilizes but not reject the host interference. Due to its nice property of utilizing but not rejecting the host interference, it has a big advantage over the host interference schemes in that the perceptual analysis can be easily implemented for our scheme to achieve the locally bounded maximum embedding strength. Thus, in this work, we detail how to implement the perceptual analysis in our double-sided schemes since the perceptual analysis is very important for improving the fidelity of watermarked contents. Through the extensive performance comparisons, we can further validate the performance advantage of our double-sided schemes.

  14. Pinning Synchronization of One-Sided Lipschitz Complex Networks

    Directory of Open Access Journals (Sweden)

    Fang Liu

    2014-01-01

    Full Text Available This paper studies the pinning synchronization in complex networks with node dynamics satisfying the one-sided Lipschitz condition which is less conservative than the well-known Lipschitz condition. Based on M-matrix theory and Lyapunov functional method, some simple pinning conditions are derived for one-sided Lipschitz complex networks with full-state and partial-state coupling, respectively. A selective pinning scheme is further provided to address the selection of pinned nodes and the design of pinning feedback gains for one-sided Lipschitz complex networks with general topologies. Numerical results are given to illustrate the effectiveness of the theoretical analysis.

  15. Elementary affine {\\lambda}-calculus with multithreading and side effects

    CERN Document Server

    Madet, Antoine

    2011-01-01

    Linear logic provides a framework to control the complexity of higher-order functional programs. We present an extension of this framework to programs with multithreading and side effects focusing on the case of elementary time. Our main contributions are as follows. First, we provide a new combinatorial proof of termination in elementary time for the functional case. Second, we develop an extension of the approach to a call-by-value \\lambda-calculus with multithreading and side effects. Third, we introduce an elementary affine type system that guarantees the standard subject reduction and progress properties. Finally, we illustrate the programming of iterative functions with side effects in the presented formalism.

  16. FLARE: The Far Side Lunar Research Expedition. A design of a far side lunar observatory

    Science.gov (United States)

    Bishop, David W.; Chakrabarty, Rudhmala P.; Hannula, Dawn M.; Hargus, William A., Jr.; Melendrez, A. Dean; Niemann, Christopher J.; Neuenschwander, Amy L.; Padgett, Brett D.; Patel, Sanjiv R.; Wiesehuegel, Leland J.

    1991-12-01

    This document outlines the design completed by members of Lone Star Aerospace, Inc. (L.S.A.) of a lunar observatory on the far side of the Moon. Such a base would not only establish a long term human presence on the Moon, but would also allow more accurate astronomical data to be obtained. A lunar observatory is more desirable than an Earth based observatory for the following reasons: instrument weight is reduced due to the Moon's weaker gravity; near vacuum conditions exist on the Moon; the Moon has slow rotation to reveal the entire sky; and the lunar surface is stable for long baseline instruments. All the conditions listed above are favorable for astronomical data recording. The technical aspects investigated in the completion of this project included site selection, mission scenario, scientific instruments, communication and power systems, habitation and transportation, cargo spacecraft design, thermal systems, robotic systems, and trajectory analysis. The site selection group focused its efforts on finding a suitable location for the observatory. Hertzsprung, a large equatorial crater on the eastern limb, was chosen as the base site.

  17. Total Limb Rotation after Unilateral Total Knee Arthroplasty: Side-to-Side Discrepancy.

    Science.gov (United States)

    Oh, Kwang-Jun; Yoon, Seok-Tae; Ko, Young-Bong

    2016-08-01

    Total limb rotation, an important anatomical feature of the lower limb, is defined as any rotation of the lower limb on its longitudinal axis. The aim of the present study was to evaluate the discrepancies of rotational profiles of total limb between nonoperated and operated limb following unilateral total knee arthroplasty. We conducted an analysis of the computed tomography (CT) data from 32 patients undergoing primary unilateral total knee arthroplasty. Using these CT scan, rotational profiles of total limb, such as femoral neck anteversion angle expressed as femoral torsion angle (FTA), tibial torsion angle (TTA), knee joint rotation angle (KJRA), and total limb rotation (TLR) were measured. There were significant discrepancies of FTA and KJRA between operated and nonoperated limb following unilateral total knee arthroplasty. The mean difference of operated and nonoperated side for FTA and KJRA were -6.51 ± 11.88 degrees (p = 0.0041) and -6.83 ± 5.04 degrees (p knee joint can lead to a total limb rotational discrepancy in patient undergoing unilateral total knee arthroplasty.

  18. Side-Scan-Sonar Lines for Hudson River, NY

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Side Scan Sonar and Subbottom Profiler Tracklines. Data was collected November 5 to December 15, 2009, in the estuary north from Saugerties to Troy. Fugro utilized...

  19. Managing Chemotherapy Side Effects: Sexual and Fertility Changes in Women

    Science.gov (United States)

    N ational C ancer I nstitute Managing Chemotherapy Side Effects Sexual and Fertility Changes in Women “Talk with your doctor before you start treatment. Ask how chemotherapy could affect your ability ...

  20. Flow characteristics at trapezoidal broad-crested side weir

    Directory of Open Access Journals (Sweden)

    Říha Jaromír

    2015-06-01

    Full Text Available Broad-crested side weirs have been the subject of numerous hydraulic studies; however, the flow field at the weir crest and in front of the weir in the approach channel still has not been fully described. Also, the discharge coefficient of broad-crested side weirs, whether slightly inclined towards the stream or lateral, still has yet to be clearly determined. Experimental research was carried out to describe the flow characteristics at low Froude numbers in the approach flow channel for various combinations of in- and overflow discharges. Three side weir types with different oblique angles were studied. Their flow characteristics and discharge coefficients were analyzed and assessed based on the results obtained from extensive measurements performed on a hydraulic model. The empirical relation between the angle of side weir obliqueness, Froude numbers in the up- and downstream channels, and the coefficient of obliqueness was derived.

  1. Graphene-based side-polished optical fiber amplifier.

    Science.gov (United States)

    Karimi, Mohammad; Ahmadi, Vahid; Ghezelsefloo, Masoud

    2016-12-20

    We demonstrate a novel design for optical fiber amplifiers, utilizing side-polished fibers with a single-layer graphene overlay as the active medium and carrier injection in the graphene layer to provide the required inversion. We study the effects of an electrically induced graphene p-i-n heterojunction in the forward bias regime on optical modes of side-polished fibers and show that gain values of 0.51, 1.81, and 1.79 dB/cm for wavelengths 1064, 1330, and 1550 nm can be obtained for single-mode side-polished fibers. Our results show that in multi-mode side-polished fibers, higher order modes experience higher values of gain, and gain can be increased by increasing polished depth. The proposed system is a tunable wideband optical amplifier that can operate for wavelengths larger than 1000 nm.

  2. Incorporating Side Information in Probabilistic Matrix Factorization with Gaussian Processes

    CERN Document Server

    Adams, Ryan Prescott; Murray, Iain

    2010-01-01

    Probabilistic matrix factorization (PMF) is a powerful method for modeling data associated with pairwise relationships, finding use in collaborative filtering, computational biology, and document analysis, among other areas. In many domains, there is additional information that can assist in prediction. For example, when modeling movie ratings, we might know when the rating occurred, where the user lives, or what actors appear in the movie. It is difficult, however, to incorporate this side information into the PMF model. We propose a framework for incorporating side information by coupling together multiple PMF problems via Gaussian process priors. We replace scalar latent features with functions that vary over the space of side information. The GP priors on these functions require them to vary smoothly and share information. We successfully use this new method to predict the scores of professional basketball games, where side information about the venue and date of the game are relevant for the outcome.

  3. The SIDER database of drugs and side effects

    DEFF Research Database (Denmark)

    Kuhn, Michael; Letunic, Ivica; Jensen, Lars Juhl;

    2016-01-01

    Unwanted side effects of drugs are a burden on patients and a severe impediment in the development of new drugs. At the same time, adverse drug reactions (ADRs) recorded during clinical trials are an important source of human phenotypic data. It is therefore essential to combine data on drugs......, targets and side effects into a more complete picture of the therapeutic mechanism of actions of drugs and the ways in which they cause adverse reactions. To this end, we have created the SIDER ('Side Effect Resource', http://sideeffects.embl.de) database of drugs and ADRs. The current release, SIDER 4......, contains data on 1430 drugs, 5880 ADRs and 140 064 drug-ADR pairs, which is an increase of 40% compared to the previous version. For more fine-grained analyses, we extracted the frequency with which side effects occur from the package inserts. This information is available for 39% of drug-ADR pairs, 19...

  4. U.S. electric utility demand-side management 1993

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-07-01

    This report presents comprehensive information on electric power industry demand-side management activities in the United States at the national, regional, and utility levels. Data is included for energy savings, peakload reductions, and costs.

  5. A Case Report of Left-Sided Headache with Rhinocleisis

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    @@ Case Report A patient, with a complaint of a left-sided headache plus a rhinocleisis for a month, was admitted to our hospital. The clinical diagnosis showed that it was a primary adenoid cystic carcinoma (ACC) of the nasopharynx.

  6. Strength Training May Prevent Side Effect of Breast Cancer Surgery

    Science.gov (United States)

    ... page: https://medlineplus.gov/news/fullstory_162473.html Strength Training May Prevent Side Effect of Breast Cancer Surgery ... 9, 2016 FRIDAY, Dec. 9, 2016 (HealthDay News) -- Strength training might benefit breast cancer survivors who've undergone ...

  7. Liraglutide and DPP-4 inhibitors - side effects comparative clinical study.

    Science.gov (United States)

    Timofte, Luminiţa; Stratmann, Bernd; Quester, Wulf; Bojiţă, Marius Traian; Tschoepe, Diethelm

    2013-01-01

    The objective of this study was to monitor the side effects of the GLP-1 receptor agonist liraglutide in comparison to those of DPP-4 inhibitors (sitagliptin and vildagliptin), in order to determine their safety, tolerability and therapeutic efficiency. The study was carried out in the "Heart and Diabetes Center NRW" and included overweight patients with type 2 diabetes whose therapeutic regimen was switched to liraglutide or DPP-4 inhibitors. A validated questionnaire method was used to monitor the side effects during the hospitalization period, then again at 3, and 6 months after the beginning of the therapy. The therapy with liraglutide was associated with more side effects than the one with DPP-4 inhibitors. In general, side effects were declining with time, thus only few patients stopped therapy. The incretin therapy turned out to be a safe and effective therapeutic option for patients with type 2 diabetes mellitus.

  8. Effect of Overlaid Material on Optical Transmission of Side-Polished Fiber Made by Wheel Side Polishing

    Institute of Scientific and Technical Information of China (English)

    Zhe Chen; Chun-He Bai

    2008-01-01

    The performance of optical power transmission through a side-polished fiber on which materials of different refractive indices were overlaid is investigated. The experiments show that the transmitted optical power through the side-polished fiber varies with the refractive index of the overlaid material. The result of our experiments fits well the theoretical calculation.Side-polished fiber manufactured by wheel polishing method can be used not only to control optical power transmission through the fiber core but also as a refractive index sensor.

  9. Persisting asymmetries of vision after right side lesions

    DEFF Research Database (Denmark)

    Habekost, Thomas; Rostrup, Egill

    2006-01-01

    Visual neglect and extinction are well-known effects of lesions in the right hemisphere. This study shows that even with minor or no clinical signs of these deficits, and in the stable phase of recovery, asymmetric visual perception is common after right side lesions. Whole, partial and colour re...... occurred selectively with bilateral stimulation. Overall, the study provided an overview of the cognitive structure and lesion anatomy of subtle visual asymmetries after right side stroke...

  10. Single Sided Messaging v. 0.6.6

    Energy Technology Data Exchange (ETDEWEB)

    2015-11-20

    Single-Sided Messaging (SSM) is a portable, multitransport networking library that enables applications to leverage potential one-sided capabilities of underlying network transports. It also provides desirable semantics that services for highperformance, massively parallel computers can leverage, such as an explicit cancel operation for pending transmissions, as well as enhanced matching semantics favoring large numbers of buffers attached to a single match entry. This release supports TCP/IP, shared memory, and Infiniband.

  11. Side Effects and Complications of Dental Materials on Oral Cavity

    OpenAIRE

    Z. Atai; M. Atai

    2007-01-01

    Development of dental materials has had a great impact on the modern dentistry. The materials ranging from polymers to metals have different applications in dentistry. Besides their important role in healing or improving the function of oral tissues, the materials may show side effects which may, in some cases, lead to severe lesions. In this review the side effects have been summarized considering a new classification for dental materials according to the duration of their applications as te...

  12. Regional renal venous hypertension and left-sided varicocele

    OpenAIRE

    O. B. Zhukov; A. V. Verzin; P. L. Penkov

    2014-01-01

    One of the most frequent correctable causes of male infertility is a varicocele. The etiology and pathogenesis of varicocele to date is a matter of debate. The aim of our study was to determine the causes and incidence of regional renal hypertension in patients with leftsided varicocele. The study involved 110 patients with left-sided varicocele in age from 18 to 35 years. Algorithm for evaluation of patients with left-sided varicocele included: physical examination, ultrasound with Doppler k...

  13. Holographic Gratings in Azobenzene Side-Chain Polymethacrylates

    DEFF Research Database (Denmark)

    Andruzzi, Luisa; Altomare, Angelina; Ciardelli, Francesco

    1999-01-01

    Optical storage properties of thin unoriented liquid crystalline and amorphous side-chain azobenzene polymethacrylate films are examined by polarization holographic measurements. The investigated materials are free radical copolymers derived from two photochromic monomers, 6-(4-oxy-4'-cyanoazoben......Optical storage properties of thin unoriented liquid crystalline and amorphous side-chain azobenzene polymethacrylate films are examined by polarization holographic measurements. The investigated materials are free radical copolymers derived from two photochromic monomers, 6-(4-oxy-4...

  14. Harmonic measures of slit sides perpendicular to the domain boundary

    CERN Document Server

    Prokhorov, Dmitri

    2012-01-01

    The article is devoted to the geometry of solutions to the chordal Loewner equation which is based on comparison of singular solutions and harmonic measures for the sides of a slit in domains generated by a driving term. It is proved that harmonic measures of two sides of a slit in the upper half-plane which is perpendicular to the real axis are asymptotically equal to each other.

  15. Left-sided gallbladder: Its clinical significance and imaging presentations

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    AIM: To assess the importance of preoperative diagnosis and presentation of left-sided gallbladder using ultrasound (US), CT and angiography.METHODS: Retrospective review of 1482 patients who underwent enhanced CT scanning was performed. Left-sided gallbladder was diagnosed if a right-sided ligamentum teres was present. The image presentations on US, CT and angiography were also reviewed.RESULTS: Left-sided gallbladder was diagnosed in nine patients. The associated abnormalities on CT imaging included portal vein anomalies, absence of umbilical portion of the portal vein in the left lobe of the liver,club-shaped portal vein in the right lobe of the liver, and difficulty in identifying segment Ⅳ. Angiography in six of nine patients demonstrated abnormal portal venous system (trifurcation type in four of six patients). The main hepatic arteries followed the portal veins in all six patients. The segment Ⅳ artery was identified in four of six patients using angiography, although segment Ⅳ was difficult to define on CT imaging. Hepatectomy was performed in three patients with concomitant liver tumor and the diagnosis of left-sided gallbladder was confirmed intraoperatively.CONCLUSION: Left-sided gallbladder is an important clinical entity in hepatectomy due to its associated portal venous and biliary anomalies. It should be considered in US, CT and angiography images that demonstrate no definite segment IV, absence of umbilical portion of the portal vein in the left lobe, and club-shaped right anterior portal vein.

  16. Prevalence of left-sided melanomas in an Irish population.

    LENUS (Irish Health Repository)

    de Blacam, C

    2011-04-17

    BACKGROUND: A predominance of melanomas on the left side of the body has recently been described. No associations between tumour laterality and gender, age or anatomical site have been identified. AIM: The aim of this study was to investigate the prevalence of left-sided melanomas in an Irish population and to examine potential associations with various patient and tumour characteristics. METHODS: A retrospective chart review of patients with cutaneous melanoma who were treated over a 10-year period was carried out. Lateral distribution of melanoma on either side of the body was compared using χ(2) analysis and evaluated by gender, age group, anatomic location, histologic subtype and Breslow depth. RESULTS: More melanomas occurred on the left side (57%, P = 0.015), and this finding was particularly significant in females. For both genders combined, there were no statistically significant differences in laterality by age group, anatomic location, type of melanoma and Breslow depth. There were significantly more superficial spreading melanomas on the left side in both men and women. CONCLUSIONS: This study demonstrates a predominance of left-sided melanomas in Irish patients. While a number of demographic and molecular associations have been proposed, further research is required to fully explain this phenomenon.

  17. Prevalence of left-sided melanomas in an Irish population.

    LENUS (Irish Health Repository)

    de Blacam, C

    2012-02-01

    BACKGROUND: A predominance of melanomas on the left side of the body has recently been described. No associations between tumour laterality and gender, age or anatomical site have been identified. AIM: The aim of this study was to investigate the prevalence of left-sided melanomas in an Irish population and to examine potential associations with various patient and tumour characteristics. METHODS: A retrospective chart review of patients with cutaneous melanoma who were treated over a 10-year period was carried out. Lateral distribution of melanoma on either side of the body was compared using chi(2) analysis and evaluated by gender, age group, anatomic location, histologic subtype and Breslow depth. RESULTS: More melanomas occurred on the left side (57%, P = 0.015), and this finding was particularly significant in females. For both genders combined, there were no statistically significant differences in laterality by age group, anatomic location, type of melanoma and Breslow depth. There were significantly more superficial spreading melanomas on the left side in both men and women. CONCLUSIONS: This study demonstrates a predominance of left-sided melanomas in Irish patients. While a number of demographic and molecular associations have been proposed, further research is required to fully explain this phenomenon.

  18. Perceived side effects of oral contraceptives among adolescent girls.

    Science.gov (United States)

    Herold, E S; Goodwin, M S

    1980-11-22

    Knowledge and attitudes of adolescent females regarding the side effects of oral contraceptives were investigated. The data source was a large study of sexual and contraceptive attitudes and experience. The questionnaire responses of 486 single females attending 10 birth control and pregnancy counseling centers in Ontario, Canada were examined. The age range of the subjects was from 13-20; 71% were attending school and 69% were living at home. They were attending the centers in order to obtain contraceptives (55%), to renew OC prescriptions (20%), or to receive pregnancy counseling (25%). 29% of the subjects had used OCs before coming to the clinic, but 91% planned to use OC after their clinic visit. 8% were planning to use an IUD; 1% were planning to use a diaphragm; and less than 1% were planning to have their boyfriend use condoms. 85% of the subjects indicated that they had heard abut side effcts of OCs with weight gain as the best known side effect. Other side effects familiar to many included nausea, circulatory disorders, headaches, emotional changes, menstrual problems and cancer. About 1/2 of the subjects had learned about these side effects from the mass media or female friends, 25% from a school sex education class, 15% from their mothers, and 3% from a physician. Despite knowledge regarding side effects, most of the subjects had positive attitudes toward OCs with 59% believing that the advnatages outweighed any disadvantages.

  19. A framework for assessing supply-side wildlife conservation.

    Science.gov (United States)

    Phelps, J; Carrasco, L R; Webb, E L

    2014-02-01

    Market-based, supply-side interventions such as domestication, cultivation, and wildlife farming have been proposed as legal substitutes for wild-collected plants and animals in the marketplace. Based on the literature, we devised a list of the conditions under which supply-side interventions may yield positive conservation outcomes. We applied it to the trade of the orchid Rhynchostylis gigantea, a protected ornamental plant. We conducted a survey of R. gigantea at Jatujak Market in Bangkok, Thailand. Farmed (legal) and wild (illegal, protected) specimens of R. gigantea were sold side-by-side at market. These results suggest farmed specimens are not being substituted for wild plants in the marketplace. For any given set of physical plant characteristics (size, condition, flowers), the origin of the plants (wild vs. farmed) did not affect price. For all price classes, farmed plants were of superior quality to wild-collected plants on the basis of most physical variables. These results suggest wild and farmed specimens represent parallel markets and may not be substitutable goods. Our results with R. gigantea highlight a range of explanations for why supply-side interventions may lack effectiveness, for example, consumer preferences for wild-collected products and low financial incentives for farming. Our results suggest that market-based conservation strategies may not be effective by themselves and may be best utilized as supplements to regulation and education. This approach represents a broad, multidisciplinary evaluation of supply-side interventions that can be applied to other plant and animal species.

  20. Interaction dynamics of gap flow with vortex-induced vibration in side-by-side cylinder arrangement

    Science.gov (United States)

    Liu, Bin; Jaiman, Rajeev K.

    2016-12-01

    A numerical investigation of the vortex-induced vibration (VIV) in a side-by-side circular cylinder arrangement has been performed in a two-dimensional laminar flow environment. One of the cylinders is elastically mounted and only vibrates in the transverse direction, while its counterpart remains stationary in a uniform flow stream. When the gap ratio is sufficiently small, the flip-flopping phenomenon of the gap flow can be an additional time-dependent interference to the flow field. This phenomenon was reported in the experimental work of Bearman and Wadcock ["The interaction between a pair of circular cylinders normal to a stream," J. Fluid Mech. 61(3), 499-511 (1973)] in a side-by-side circular cylinder arrangement, in which the gap flow deflects toward one of the cylinders and switched its sides intermittently. Albeit one of the two cylinders is free to vibrate, the flip-flop of a gap flow during VIV dynamics can still be observed outside the lock-in region. The exact moments of the flip-flop phenomenon due to spontaneous symmetry breaking are observed in this numerical study. The significant characteristic vortex modes in the near-wake region are extracted via dynamic modal analysis and the interference between the gap flow and VIV is found to be mutual. In a vibrating side-by-side arrangement, the lock-in region with respect to reduced velocity becomes narrower due to the interference from its stationary counterpart. The frequency lock-in occurs and ends earlier than that of an isolated vibrating circular cylinder subjected to an identical flow environment. Similar to a tandem cylinder arrangement, in the post-lock-in region, the maximum vibration amplitudes are escalated compared with those of an isolated circular cylinder configuration. On the other hand, subjected to the influence from VIV, the biased gap flow deflects toward the vibrating cylinder quasi-stably during the frequency lock-in process. This behavior is different from the reported bi

  1. Meta-sided Exchange Rings and Their Extensions%Meta-sided exchange环及其扩张

    Institute of Scientific and Technical Information of China (English)

    郭莉琴; 何建伟; 卲海琴

    2010-01-01

    讨论了meta-sided exchange环的性质.证明了如果R是Abelian meta-sided exchange环,则对R的任意素理想P,都有R/P是局部环;如果R是Abelian环,(S,≤)是严格序幺半群且对任意s∈S,都有0≤s,则广义幂级数环[[RS,≤

  2. Application of side-to-side anastomosis of the lesser curvature of stomach and jejunum in gastric bypass

    Science.gov (United States)

    Bai, Ri-Xing; Yan, Wen-Mao; Li, You-Guo; Xu, Jun; Zhong, Zhi-Qiang; Yan, Ming

    2016-01-01

    AIM To evaluate the feasibility of side-to-side anastomosis of the lesser curvature of stomach and jejunum in laparoscopic Roux-en-Y gastric bypass (LRYGB). METHODS Seventy-seven patients received side-to-side anastomosis of the lesser curvature of stomach and jejunum by utilization of linear stapler in LRYGB from April 2012 to July 2015 were retrospectively analyzed. RESULTS All patients were successfully completed laparoscopic gastric bypass with the side-to-side anastomosis of the lesser curvature of stomach and jejunum. No patient was switched to laparotomy during operation. No early complications including gastrointestinal anastomotic bleeding, fistula, obstruction, deep vein thrombosis, incision infections, intra-abdominal hernia complications were found. One patient complicated with stricture of gastrojejunal anastomosis (1.3%) and six patients complicated with incomplete intestinal obstruction (7.8%). BMI and HbA1c determined at 3, 6, 12, 24 mo during follow up period were significantly reduced compared with preoperative baselines respectively. The percentage of patients who maintain HbA1c (%) < 6.5% without taking antidiabetic drugs reached to 61.0%, 63.6%, 75.0%, and 63.6% respectively. The outcome parameters of concomitant diseases were significantly improved too. CONCLUSION Present surgery is a safety and feasibility procedure. It is effective to lighten the body weight of patients and improve type 2 diabetes and related complications. PMID:27729746

  3. A protein-dependent side-chain rotamer library.

    KAUST Repository

    Bhuyan, M.S.

    2011-12-14

    Protein side-chain packing problem has remained one of the key open problems in bioinformatics. The three main components of protein side-chain prediction methods are a rotamer library, an energy function and a search algorithm. Rotamer libraries summarize the existing knowledge of the experimentally determined structures quantitatively. Depending on how much contextual information is encoded, there are backbone-independent rotamer libraries and backbone-dependent rotamer libraries. Backbone-independent libraries only encode sequential information, whereas backbone-dependent libraries encode both sequential and locally structural information. However, side-chain conformations are determined by spatially local information, rather than sequentially local information. Since in the side-chain prediction problem, the backbone structure is given, spatially local information should ideally be encoded into the rotamer libraries. In this paper, we propose a new type of backbone-dependent rotamer library, which encodes structural information of all the spatially neighboring residues. We call it protein-dependent rotamer libraries. Given any rotamer library and a protein backbone structure, we first model the protein structure as a Markov random field. Then the marginal distributions are estimated by the inference algorithms, without doing global optimization or search. The rotamers from the given library are then re-ranked and associated with the updated probabilities. Experimental results demonstrate that the proposed protein-dependent libraries significantly outperform the widely used backbone-dependent libraries in terms of the side-chain prediction accuracy and the rotamer ranking ability. Furthermore, without global optimization/search, the side-chain prediction power of the protein-dependent library is still comparable to the global-search-based side-chain prediction methods.

  4. Demand Side Management Performance Evaluation for Commercial Enterprises

    Directory of Open Access Journals (Sweden)

    Jun Dong

    2016-10-01

    Full Text Available Demand Side Management in power systems plays an important role in ensuring a reliable power supply and protecting the environment. Demand Side Management in the commercial sector is vital for sustainable development during China’s industrial restructuring. A hybrid multi-criteria decision making framework for evaluating Demand Side Management performance of commercial enterprises is proposed from a sustainability perspective. A fuzzy Analytic Hierarchy Process is employed to determine the weights of the criteria and a fuzzy technique for order preference by similarity to an ideal solution is applied to rank Demand Side Management performance. An evaluation index system is built, containing economic, social, environmental and technical criteria associated with 15 sub-criteria. Four groups of expert panels from government departments, research institutions, electricity utilities and commercial enterprises gave judgments on criteria weights and criteria performances for alternatives. The effectiveness of the proposed hybrid framework was demonstrated through a case study in Beijing, in which Demand Side Management performances of four alternatives were ranked. Sensitivity analysis results indicate that the hybrid framework is robust.

  5. Sex differences in substance use disorders: focus on side effects.

    Science.gov (United States)

    Agabio, Roberta; Campesi, Ilaria; Pisanu, Claudia; Gessa, Gian Luigi; Franconi, Flavia

    2016-09-01

    Although sex differences in several aspects of substance use disorders (SUDs) have been identified, less is known about the importance of possible sex differences in side effects induced by substances of abuse or by medications used to treat SUDs. In the SUD field, the perception of certain subjective effects are actively sought, while all other manifestations might operationally be considered side effects. This article was aimed at reviewing sex differences in side effects induced by alcohol, nicotine, heroin, marijuana and cocaine and by medications approved for alcohol, nicotine and heroin use disorders. A large body of evidence suggests that women are at higher risk of alcohol-induced injury, liver disease, cardiomyopathy, myopathy, brain damages and mortality. The risk of tobacco-induced coronary heart disease, lung disease and health problems is higher for women than for men. Women also experience greater exposure to side effects induced by heroin, marijuana and cocaine. In addition, women appear to be more vulnerable to the side effects induced by medications used to treat SUDs. Patients with SUDs should be advised that the risk of developing health problems may be higher for women than for men after consumption of the same amount of substances of abuse. Doses of medications for SUD women should be adjusted at least according to body weight. The sex differences observed also indicate an urgent need to recruit adequate numbers of female subjects in pre-clinical and clinical studies to improve our knowledge about SUDs in women.

  6. Novel high torque bearingless two-sided rotary ultrasonic motor

    Institute of Scientific and Technical Information of China (English)

    LI Xia; CHEN Wei-shan; XIE Tao; LIU Jun-kao

    2007-01-01

    Applications are limited at present because the currently available ultrasonic motors (USMs) do not provide sufficiently high torque and power. The conventional travelling-wave USM needs the bearing to support, which required lubricant. To solve the above problem, a bearingless travelling-wave USM is designed. First, a novel structure of the two-sided USM consisting ora two-sided teeth stator and two disk-type rotors is designed. And the excitation principle of the two-sided travelling-wave USM is analyzed. Then, using ANSYS software, we set up the model of the stator to predict the excitation frequency and modal response of the stator. The shape of the vibration mode was obtained. Last, the load characteristics of the USM are measured using experimental method. The maximum stall torque and the no-load speed were obtained. The results showed that the characteristics of the two-sided USM are better than those of the conventional one-sided USM.

  7. Predicting bed form roughness: the influence of lee side angle

    Science.gov (United States)

    Lefebvre, Alice; Winter, Christian

    2016-04-01

    Flow transverse bedforms (ripples and dunes) are ubiquitous in rivers and coastal seas. Local hydrodynamics and transport conditions depend on the size and geometry of these bedforms, as they constitute roughness elements at the bed. Bedform influence on flow energy must be considered for the understanding of flow dynamics, and in the development and application of numerical models. Common estimations or predictors of form roughness (friction factors) are based mostly on data of steep bedforms (with angle-of-repose lee slopes), and described by highly simplified bedform dimensions (heights and lengths). However, natural bedforms often are not steep, and differ in form and hydraulic effect relative to idealised bedforms. Based on systematic numerical model experiments, this study shows how the hydraulic effect of bedforms depends on the flow structure behind bedforms, which is determined by the bedform lee side angle, aspect ratio and relative height. Simulations reveal that flow separation behind bedform crests and, thus, a hydraulic effect is induced at lee side angles steeper than 11 to 18° depending on relative height, and that a fully developed flow separation zone exists only over bedforms with a lee side angle steeper than 24°. Furthermore, the hydraulic effect of bedforms with varying lee side angle is evaluated and a reduction function to common friction factors is proposed. A function is also developed for the Nikuradse roughness (k s), and a new equation is proposed which directly relates k s to bedform relative height, aspect ratio and lee side angle.

  8. Early and Late Side Effects Associated with Photo(chemotherapy

    Directory of Open Access Journals (Sweden)

    Günseli Öztürk

    2010-12-01

    Full Text Available Phototherapy (PUVA ve UVB is a widely used and effective treatment method for a variety of dermatological diseases. Adverse effects associated with phototherapy can be classified as acute and chronic side effects. Acute side effects are mostly related with UV doses and drug intolerance, and include itching, nausea, erythema, edema and phototoxic reactions that sometimes blister formation is seen. Acute side effects are usually moderate and transient. Chronic side effects of phototherapy are early aging of skin, pigmentary changes and increased risk of skin carcinogenesis. The major concern is development of skin cancer. This risk is especially related to long-term exposure and high cumulative doses of PUVA, increase in time and is persistent. Therefore, risk/advantage ratio of phototherapy should be carefully evaluated in each patient, and treatment protocols with minimal UV exposure should be chosen according to the phototherapy guides. Follow-up of the patients for long terms is important in prevention or in reduction of this risk by detecting and treating any premalignant or malignant lesion early. In this article, acute and chronic side effects of phototherapy are reviewed with recent literature findings.

  9. Source Coding When the Side Information May Be Delayed

    CERN Document Server

    Simeone, Osvaldo

    2011-01-01

    For memoryless sources, delayed side information at the decoder does not improve the rate-distortion function. However, this is not the case for more general sources with memory, as demonstrated by a number of works focusing on the special case of (delayed) feedforward. In this paper, a setting is studied in which the encoder is potentially uncertain about the delay with which measurements of the side information are acquired at the decoder. Assuming a hidden Markov model for the sources, at first, a single-letter characterization is given for the set-up where the side information delay is arbitrary and known at the encoder, and the reconstruction at the destination is required to be (near) lossless. Then, with delay equal to zero or one source symbol, a single-letter characterization is given of the rate-distortion region for the case where side information may be delayed or not, unbeknownst to the encoder. The characterization is further extended to allow for additional information to be sent when the side ...

  10. 'Side effects' of health promotion: an example from Austrian schools.

    Science.gov (United States)

    Gugglberger, Lisa; Flaschberger, Edith; Teutsch, Friedrich

    2014-07-04

    While the existence of side effects of medical interventions is common knowledge and widely investigated, possible unintended effects of health promotion (HP) interventions are only sparsely discussed in the HP literature. Drawing on qualitative evaluation data generated within an on-going process evaluation of a regional health-promoting schools network in Austria, we demonstrate which desirable and undesirable effects HP practice can have for teachers. Thirteen group discussions with teachers (n = 63) and headteachers (n = 9) acting as health coordinators in the network schools were conducted between 2010 and 2013. These data were analysed using systems and thematic analyses. In our example, desirable side effects included health coordinators gaining new relationships, new skills and benefiting from improved infrastructure. The undesirable side effects centred on stress, work overload and frustration, due to the additional work brought about by HP practice, negative reactions by colleagues as well as by technicalities of the network. The undesirable side effects of HP predominated in our study, pointing to several implications like the need to accommodate the concept of HP in the teachers' core responsibilities; the participation of all staff members and students in a whole-school approach toward SHP, and the need for changes on an organizational level. Based on this study, we come to the conclusion that a systematic approach to investigating and analysing side effects of HP is currently lacking in HP research and suggest that theoretical examination and more empirical research is needed.

  11. Side Channel Passive Quantum Key Distribution with One Uninformative State

    Science.gov (United States)

    Kang, Guo-Dong; Zhou, Qing-Ping; Fang, Mao-Fa

    2017-03-01

    In most of quantum key distribution schemes, real random number generators are required on both sides for preparation and measurement bases choice. In this paper, via entangled photon pairs, we present a side channel passive quantum key distribution scheme, in which random number generator is unneeded on the receiver side. On the sender Alice side, along with massive of signal photons, small amount of uninformative photons are randomly sent to her partner Bob for eavesdropper-presence testing and error estimation. While on the other side channel, without using random number generator Bob do not actively measure the income signals randomly in two non-orthogonal bases. Instead, he just passively register photon click events, in two settled symmetric (i.e. X) bases, and the raw key(click events) is the probable outcomes of a special quantum measurement module constructed by Alice and Bob. Further, security analysis and formulas of security bounds for this scheme is also investigated under reasonable assumptions. Our work shows that the uninformative state employed in this paper is powerful to fight against eavesdropper Eve.

  12. Interstrand side chain--side chain interactions in a designed beta-hairpin: significance of both lateral and diagonal pairings.

    Science.gov (United States)

    Syud, F A; Stanger, H E; Gellman, S H

    2001-09-12

    The contributions of interstrand side chain-side chain contacts to beta-sheet stability have been examined with an autonomously folding beta-hairpin model system. RYVEV(D)PGOKILQ-NH2 ((D)P = D-proline, O = ornithine) has previously been shown to adopt a beta-hairpin conformation in aqueous solution, with a two-residue loop at D-Pro-Gly. In the present study, side chains that display interstrand NOEs (Tyr-2, Lys-9, and Leu-11) are mutated to alanine or serine, and the conformational impact of the mutations is assessed. In the beta-hairpin conformation Tyr-2 and Leu-11 are directly across from one another (non-hydrogen bonded pair). This "lateral" juxtaposition of two hydrophobic side chains appears to contribute to beta-hairpin conformational stability, which is consistent with results from other beta-sheet model studies and with statistical analyses of interstrand residue contacts in protein crystal structures. Interaction between the side chains of Tyr-2 and Lys-9 also stabilizes the beta-hairpin conformation. Tyr-2/Lys-9 is a "diagonal" interstrand juxtaposition because these residues are not directly across from one another in terms of the hydrogen bonding registry between the strands. This diagonal interaction arises from the right-handed twist that is commonly observed among beta-sheets. Evidence of diagonal side chain-side chain contacts has been observed in other autonomously folding beta-sheet model systems, but we are not aware of other efforts to determine whether a diagonal interaction contributes to beta-sheet stability.

  13. Čerenkov free-electron laser with side walls

    Energy Technology Data Exchange (ETDEWEB)

    Kalkal, Yashvir, E-mail: yashvirkalkal@gmail.com [Homi Bhabha National Institute, Mumbai 400094 (India); Accelerator and Beam Physics Laboratory, Raja Ramanna Centre for Advanced Technology, Indore 452013 (India); Kumar, Vinit [Homi Bhabha National Institute, Mumbai 400094 (India); Accelerator and Beam Physics Laboratory, Raja Ramanna Centre for Advanced Technology, Indore 452013 (India)

    2016-08-11

    In this paper, we have proposed a Čerenkov free-electron laser (CFEL) with metallic side walls, which are used to confine an electromagnetic surface mode supported by a thin dielectric slab placed on top of a conducting surface. This leads to an enhancement in coupling between the optical mode and the co-propagating electron beam, and consequently, performance of the CFEL is improved. We set up coupled Maxwell–Lorentz equations for the system, in analogy with an undulator based conventional FEL, and obtain formulas for the small-signal gain and growth rate. It is shown that small signal gain and growth rate in this configuration are larger compared to the configuration without the side walls. In the nonlinear regime, we solve the coupled Maxwell–Lorentz equations numerically and study the saturation behaviour of the system. It is found that the Čerenkov FEL with side walls saturates quickly, and produces powerful coherent terahertz radiation.

  14. Endocrine side effects of broad-acting kinase inhibitors.

    Science.gov (United States)

    Lodish, Maya B; Stratakis, Constantine A

    2010-09-01

    Targeted therapy in oncology consists of drugs that specifically interfere with abnormal signaling pathways that are dysregulated in cancer cells. Tyrosine kinase inhibitors (TKIs) take advantage of unique oncogenes that are activated in certain types of cancer, and also target common mechanisms of growth, invasion, metastasis, and angiogenesis. However, many kinase inhibitors for cancer therapy are somewhat nonselective, and most have additional mechanisms of action at the cellular level, which are not completely understood. The use of these agents has increased our knowledge of important side effects, of which the practicing clinician must be aware. Recently, proposed endocrine-related side effects of these agents include alterations in thyroid function, bone metabolism, linear growth, gonadal function, fetal development, and glucose metabolism, and adrenal function. This review summarizes the most recent data on the endocrine side effects of TKIs.

  15. Čerenkov free-electron laser with side walls

    Science.gov (United States)

    Kalkal, Yashvir; Kumar, Vinit

    2016-08-01

    In this paper, we have proposed a Čerenkov free-electron laser (CFEL) with metallic side walls, which are used to confine an electromagnetic surface mode supported by a thin dielectric slab placed on top of a conducting surface. This leads to an enhancement in coupling between the optical mode and the co-propagating electron beam, and consequently, performance of the CFEL is improved. We set up coupled Maxwell-Lorentz equations for the system, in analogy with an undulator based conventional FEL, and obtain formulas for the small-signal gain and growth rate. It is shown that small signal gain and growth rate in this configuration are larger compared to the configuration without the side walls. In the nonlinear regime, we solve the coupled Maxwell-Lorentz equations numerically and study the saturation behaviour of the system. It is found that the Čerenkov FEL with side walls saturates quickly, and produces powerful coherent terahertz radiation.

  16. Amantadine in the treatment of neuroendocrine side effects of neuroleptics.

    Science.gov (United States)

    Correa, N; Opler, L A; Kay, S R; Birmaher, B

    1987-04-01

    An open-label reversal drug study was undertaken on 10 neuroleptic-treated schizophrenic inpatients to assess the impact of amantadine hydrochloride on presumed prolactin-mediated neuroendocrine side effects. Measures were conducted across 7 weeks, including a 2-week neuroleptic baseline, a 3-week neuroleptic-plus-amantadine phase, and a 2-week return to the baseline regimen. Significant reduction with amantadine was observed on all six indices of neuroendocrine side effects: serum prolactin levels, body weight, gynecomastia/galactorrhea, breast tenderness, decreased libido, and amenorrhea. Improvement on these parameters was noted for as many as nine or all 10 patients, while in no cases was there worsening. In terms of motor and clinical effects, significant diminution of extrapyramidal and psycho-pathological symptoms was also achieved during this phase. The results suggested that amantadine may be beneficial for the treatment of neuro-endocrine side effects of antipsychotic medication owing to its ability to reverse neuroleptic-induced hyperprolactinemia.

  17. Development, prototyping and characterization of double sided silicon strip detectors

    Science.gov (United States)

    Topkar, Anita; Singh, Arvind; Aggarwal, Bharti; Kumar, Amit; Kumar, Arvind; Murali Krishna, L. V.; Das, D.

    2016-10-01

    Double sided DC-coupled silicon strip detectors with geometry of 65 mm×65 mm have been developed in India for nuclear physics experiments. The detectors have 64 P+ strips on the front side and 64 N+ strips on the backside with a pitch of 0.9 mm. These detectors were fabricated using a twelve mask layer process involving double sided wafer processing technology. Semiconductor process and device simulations were carried out in order to theoretically estimate the impact of important design and process parameters on the breakdown voltage of detectors. The performance of the first lot of prototype detectors has been studied using static characterization tests and using an alpha source. The characterization results demonstrate that the detectors have low leakage currents and good uniformity over the detector area of about 40 cm2. Overview of the detector design, fabrication process, simulation results and initial characterization results of the detectors are presented in this paper.

  18. U.S. electric utility demand-side management 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-12-01

    The US Electric Utility Demand-Side Management report presents comprehensive information on electric power industry demand-side management (DSM) activities in the US at the national, regional, and utility levels. The objective of the publication is to provide industry decision makers, government policy makers, analysts, and the general public with historical data that may be used in understanding DSM as it related to the US electric power industry. The first chapter, ``Profile: U.S. Electric Utility Demand-Side Management,`` presents a general discussion of DSM, its history, current issues, and a review of key statistics for the year. Subsequent chapters present discussions and more detailed data on energy savings, peak load reductions and costs attributable to DSM. 9 figs., 24 tabs.

  19. U.S. electric utility demand-side management 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-01-01

    The US Electric Utility Demand-Side Management report is prepared by the Coal and Electric Data and Renewables Division; Office of Coal, Nuclear, Electric and Alternative Fuels; Energy Information Administration (EIA); US Department of Energy. The report presents comprehensive information on electric power industry demand-side management (DSM) activities in the US at the national, regional, and utility levels. The objective of the publication is to provide industry decision makers, government policy makers, analysts, and the general public with historical data that may be used in understanding DSM as it relates to the US electric power industry. The first chapter, ``Profile: US Electric Utility Demand-Side Management``, presents a general discussion of DSM, its history, current issues, and a review of key statistics for the year. Subsequent chapters present discussions and more detailed data on energy savings, peak load reductions and costs attributable to DSM. 9 figs., 24 tabs.

  20. The Dark Side of Computer-Mediated Control

    DEFF Research Database (Denmark)

    Cunha, J. V.; Carugati, Andrea; Leclercq, A.

    2015-01-01

    Research on the dark side of computer-mediated control has explained the consequences of computer-mediated control when work is tightly coupled with its electronic representation because information systems record work automatically. Our study complements prior research by addressing the dark side...... of computer-mediated control when work and its electronic representation are loosely coupled, because it is employees who report their work in IT systems. Data from a 15-month ethnographic study of the appropriation of a customer relationship management system in the sales department of a large organization...... reveal that loosely versus tightly coupled computer-mediated control produce key differences that re-specify the dark side of computer-mediated control....

  1. Three-Receiver Broadcast Channels with Side Information

    CERN Document Server

    Hajizadeh, Saeed

    2012-01-01

    Three-receiver broadcast channel (BC) is of interest due to its information theoretical differences with two receiver one. In this paper, we derive achievable rate regions for two classes of 3-receiver BC with side information available at the transmitter, Multilevel BC and 3-receiver less noisy BC, by using superposition coding, Gel'fand-Pinsker binning scheme and Nair-El Gamal indirect decoding. Our rate region for multilevel BC subsumes the Steinberg rate region for 2-receiver degraded BC with side information as its special case. We also find the capacity region of 3-receiver less noisy BC when side information is available both at the transmitter and at the receivers.

  2. Variable-focus side-firing endoscopic device

    Science.gov (United States)

    Lemberg, Vladimir G.; Black, Michael

    1996-05-01

    Conventional side-firing fiber technology exhibits performance limitations and utilizes expensive single-use only devices which often require multiple fibers for laser prostatectomy. Another limitation of existing side-firing fiber technology is its inability to focus the beam to create incisions for urologic applications such as laser TURP (transurethral resectional prostatectomy), tumor necrosis, lithotripsy, genital warts, and photodynamic therapy. Newly introduced variable-focus side-firing endoscopic device utilizes either one or two lenses and a mirror, onto a single cylinder of molded glass. The laser beam exits the optical fiber, passes through the lens, strikes the cylindrical mirror, and traverses the cylindrical surface. Depending on the design, the laser beam is reflected at the angles ranging from 30 degrees to 120 degrees out of the cylindrical lens. A second lens can be formed onto the side of the cylindrical surface at the beam's exit point. Another advantage of the innovative side-firing device is its capability to provide versatile matching to multiple laser wavelengths from 360 nm to 2.5 microns, and achieve power densities great enough to perform vaporization, incision and coagulation of tissue. Precise focusing of the laser beam results in reduced tissue necrosis of surrounding the treatment area as well as in decreased laser radiation back-scattering. Surgeons can very the focus by adjusting the distance from the tip to the target area. The variable focus side-firing device provides a focused beam at the range of 1.0 to 1.5 mm, for incision. Outside this range, it produces a defocused beam for coagulation.

  3. Robotic complete mesocolic excision for right-sided colon cancer.

    Science.gov (United States)

    Ozben, Volkan; Baca, Bilgi; Atasoy, Deniz; Bayraktar, Onur; Aghayeva, Afag; Cengiz, Turgut Bora; Erguner, Ilknur; Karahasanoglu, Tayfun; Hamzaoglu, Ismail

    2016-10-01

    Complete mesocolic excision (CME) with central vascular ligation for right-sided colon cancer has been proven to provide superior oncologic outcomes and survival advantage when compared to standard lymphadenectomy [1]. A number of studies comparing conventional laparoscopic versus open CME have shown feasibility and safety of the laparoscopic approach with acceptable oncological profile and postoperative outcomes [2, 3]. The introduction of robotic systems with its technical advantages, including improved vision, better ergonomics and precise dissection, has further revolutionized minimally invasive approach in colorectal surgery. However, there seems to be a relatively slow adoption of robotic approach in the CME technique for right-sided colon cancer. This video demonstrates our detailed operative technique and feasibility for performing right-sided CME robotically. The surgical procedure is performed with a medial-to-lateral approach through four 8-mm robotic and one assistant ports. First, the ileocolic vessels are isolated, clipped and transected near their origins. Cephalad dissection continues along the ventral aspect of the superior mesenteric vein. Staying in the embryological planes between the mesocolon and retroperitoneal structures, mesenteric dissection is extended up to the root of the right colic vessels, if present, and the middle colic vessels, which are clipped and divided individually near their origins. After the terminal ileum is transected using an endolinear staple, the colon is mobilized fully from gastrocolic tissue and then from its lateral attachments. The transverse colon is transected under the guidance of near-infrared fluorescence imaging. Creation of an intracorporeal side-to-side ileotransversostomy anastomosis and extraction of the specimen complete the operation. We consider robotic CME to be feasible, safe and oncologically adequate for the treatment of right-sided colon cancer. Its technical advantages may lead to further

  4. Two-Sided Gravitational Mirror: Sealing off Curvature Singularities

    CERN Document Server

    Davidson, Aharon

    2012-01-01

    A gravitational mirror is a non-singular finite redshift surface which bounces all incident null geodesics. While a white mirror (outward bouncing) resembles 't Hooft's brick wall, a black mirror (inward bouncing) offers a novel mechanism for sealing off curvature singularities. The geometry underlying a two-sided mirror is characterized by a single signature change, to be contrasted with the signature flip which governs the black hole geometry. To demonstrate the phenomenon analytically, we derive an exact, static, radially symmetric, two-sided mirror solution, which asymptotes the massless BTZ black hole background, and then probe the local structure of a massive mirror.

  5. Collusion in Markets with Imperfect Price Information on Both Sides

    DEFF Research Database (Denmark)

    Schultz, Christian

    The paper considers tacit collusion in markets which are not fully transparent on both sides. Consumers only detect prices with some probability before deciding which firm to purchase from, and each firm only detects the other firm's price with some probability. Increasing transparency on the pro......The paper considers tacit collusion in markets which are not fully transparent on both sides. Consumers only detect prices with some probability before deciding which firm to purchase from, and each firm only detects the other firm's price with some probability. Increasing transparency...

  6. The veto system of the DarkSide-50 experiment

    CERN Document Server

    Agnes, P; Albuquerque, I F M; Alexander, T; Alton, A K; Arisaka, K; Back, H O; Baldin, B; Biery, K; Bonfini, G; Bossa, M; Bottino, B; Brigatti, A; Brodsky, J; Budano, F; Bussino, S; Cadeddu, M; Cadonati, L; Cadoni, M; Calaprice, F; Canci, N; Candela, A; Cao, H; Cariello, M; Carlini, M; Catalanotti, S; Cavalcante, P; Chepurnov, A; Cocco, A G; Covone, G; Crippa, L; D'Angelo, D; D'Incecco, M; Davini, S; De Cecco, S; De Deo, M; De Vincenzi, M; Derbin, A; Devoto, A; Di Eusanio, F; Di Pietro, G; Edkins, E; Empl, A; Fan, A; Fiorillo, G; Fomenko, K; Foster, G; Franco, D; Gabriele, F; Galbiati, C; Giganti, C; Goretti, A M; Granato, F; Grandi, L; Gromov, M; Guan, M; Guardincerri, Y; Hackett, B R; Herner, K R; Hungerford, E V; Ianni, Aldo; Ianni, Andrea; James, I; Johnson, T; Jollet, C; Keeter, K; Kendziora, C L; Kobychev, V; Koh, G; Korablev, D; Korga, G; Kubankin, A; Li, X; Lissia, M; Lombardi, P; Luitz, S; Ma, Y; Machulin, I N; Mandarano, A; Mari, S M; Maricic, J; Marini, L; Martoff, C J; Meregaglia, A; Meyers, P D; Miletic, T; Milincic, R; Montanari, D; Monte, A; Montuschi, M; Monzani, M E; Mosteiro, P; Mount, B J; Muratova, V N; Musico, P; Napolitano, J; Nelson, A; Odrowski, S; Orsini, M; Ortica, F; Pagani, L; Pallavicini, M; Pantic, E; Parmeggiano, S; Pelczar, K; Pelliccia, N; Perasso, S; Pocar, A; Pordes, S; Pugachev, D A; Qian, H; Randle, K; Ranucci, G; Razeto, A; Reinhold, B; Renshaw, A L; Romani, A; Rossi, B; Rossi, N; Rountree, S D; Sablone, D; Saggese, P; Saldanha, R; Sands, W; Sangiorgio, S; Savarese, C; Segreto, E; Semenov, D A; Shields, E; Singh, P N; Skorokhvatov, M D; Smirnov, O; Sotnikov, A; Stanford, C; Suvorov, Y; Tartaglia, R; Tatarowicz, J; Testera, G; Tonazzo, A; Trinchese, P; Unzhakov, E V; Vishneva, A; Vogelaar, B; Wada, M; Walker, S; Wang, H; Wang, Y; Watson, A W; Westerdale, S; Wilhelmi, J; Wojcik, M M; Xiang, X; Xu, J; Yang, C; Yoo, J; Zavatarelli, S; Zec, A; Zhong, W; Zhu, C; Zuzel, G

    2015-01-01

    Nuclear recoil events produced by neutron scatters form one of the most important classes of background in WIMP direct detection experiments, as they may produce nuclear recoils that look exactly like WIMP interactions. In DarkSide-50, we both actively suppress and measure the rate of neutron-induced background events using our neutron veto, composed of a boron-loaded liquid scintillator detector within a water Cherenkov detector. This paper is devoted to the description of the neutron veto system of DarkSide-50, including the detector structure, the fundamentals of event reconstruction and data analysis, and basic performance parameters.

  7. US electric utility demand-side management, 1994

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-12-26

    The report presents comprehensive information on electric power industry demand-side management (DSM) activities in US at the national, regional, and utility levels. Objective is provide industry decision makers, government policy makers, analysts, and the general public with historical data that may be used in understanding DSM as it relates to the US electric power industry. The first chapter, ``Profile: US Electric Utility Demand-Side Management,`` presents a general discussion of DSM, its history, current issues, and a review of key statistics for the year. Subsequent chapters present discussions and more detailed data on energy savings, peak load reductions, and costs attributable to DSM.

  8. Two consecutive levels of unilateral cervical spondylolysis on opposite sides

    Energy Technology Data Exchange (ETDEWEB)

    Ryu, Kyeong Hwa; Kim, Seon Jeong; KIm Ok Hwa; Kim, Seung Ho; Lee, Kwang Hwi; Beak, Hye Jin; Lee, Ye Daun [Dept. of Radiology, Inje University College of Medicine, Haeundae Paik Hospital, Busan (Korea, Republic of); Cha, Yoon Ki [Dept. of Radiology, Dongguk University College of Medicine, Ilsan Hospital, Goyang (Korea, Republic of)

    2015-09-15

    Cervical spondylolysis, with or without spondylolisthesis, is a rare condition defined as a corticated cleft between the superior and inferior articular facets of the articular pillar. The defect occurs predominantly at C6, and is usually bilateral in up to two-thirds of cases. Multilevel involvement is uncommon, however, to date, no case of two consecutive levels of unilateral cervical spondylolysis on opposite sides has been reported. Here, we report a rare case of a patient affected by two consecutive levels of unilateral cervical spondylolysis at C5 and C6 on opposite sides in a 19-year-old male complaining of neck pain.

  9. FINANCIAL SIDE ANALYSIS OF LOCAL AUTONOMY IN ROMANIA

    Directory of Open Access Journals (Sweden)

    ICHIM CRISTINEL

    2012-05-01

    Full Text Available Financial side of local autonomy expresses the capacity of local communities to have their own revenue and expenditure budget, distinct from that of the state in which revenues can cover expenses incurred to meet their requirements. The analysis of financial autonomy of administrative-territorial units in Romania is an interesting but complex approach given that some factors are actually difficult to predict and quantify.The purpose of this paper is to clarify the meaning of financial side of local autonomy and analyze this in Romania based on indicators established in recent years for measuring the position of administrative-territorial units in relation to central government.

  10. The contribution of specific organelles to side scatter

    Science.gov (United States)

    Mourant, Judith R.; Marina, Oana C.; Sanders, Claire K.

    2013-02-01

    Knowledge of which cellular structures scatter light is needed to fully utilize the information available from light scattering measurements of cells and tissues. To determine how specific organelles contribute to light scattering, wide angle side scattering was imaged simultaneously with fluorescence from specific organelles for thousands of cells using flow cytometry. Images were obtained with different depth of field conditions and analyzed with different assumptions. Both sets of data demonstrated that mitochondria and lysosomes, contribute similarly to side scatter. The nucleus contributes as much or more light scatter than either the mitochondria or the lysosomes.

  11. Integrated resource strategic planning and power demand-side management

    CERN Document Server

    Hu, Zhaoguang; Wen, Quan

    2013-01-01

    Integrated Resource Strategic Planning and Power Demand-Side Management elaborates two important methods - Integrated Resource Strategic Planning (IRSP) and Demand Side Management (DSM) - in terms of methodology modeling, case studies and lessons learned. This book introduces a prospective and realistic theory of the IRSP method and includes typical best practices of DSM for energy conservation and emission reduction in different countries. It can help energy providers and governmental decision-makers formulate policies and make plans for energy conservation and emission reduction, and can hel

  12. Misoprostol Induced Convulsion-A Rare Side Effect of Misoprostol

    Science.gov (United States)

    Das, Rituparna; Ahanthem, Santa Singh; Reddy, Kalyani

    2017-01-01

    Misoprostol, a synthetic prostaglandin E1 has wider application in obstetrics gynaecology. It has been recommended in the prophylaxis and treatment of Post Partum Haemorrhage (PPH) by Federation of Obstetrics and Gynaecology (FIGO), World Health Organisation (WHO) and American College of Obstetrics and Gynaecology (ACOG). It is a very safe drug associated with transient side-effects like fever, chills, nausea, vomiting, diarrhoea and abdominal pain. In the present case report patient had an unusual side effect of hyperpyrexia and convulsion after use of misoprostol for prophylaxis against PPH.

  13. Advanced Front-Side Technology in Crystalline Silicon Solar Cells (Geavanceerde Frontend-Side Technolgy in kristallijn silicium zonnecellen)

    OpenAIRE

    2013-01-01

    The goal of this thesis is to improve the efficiency of silicon solar cells such that the cost/watt could be reduced to a competitive level. In this thesis, three aspects of the front-side of crystalline silicon solar cells have been investigated. Advanced texturing, emitter formation and passivation are detailed in chapters 2, 3 and 4 respectively. Below, each chapter is summarized. In chapter 2, a new technique has been developed that textures the frontside while polishing the rear-side. Th...

  14. Supply-side-demand-side optimization and cost-environment trade offs for China`s coal and electricity system

    Energy Technology Data Exchange (ETDEWEB)

    Xie Zhijun; Kuby, M. [Boston University, Boston, MA (United States). Dept. of Geography, Center for Energy and Environmental Studies

    1997-02-01

    The authors simultaneously optimize supply-side and demand-size investments for satisfying China`s coal and electricity needs over a 15 year time horizon. The results are compared to equivalent results from a supply-side only optimization assuming a business-as-usual demand scenario. It is estimated that, by shifting investment from energy production and transportation to energy efficiency improvement, China could meet the same energy service demand in 2000 for 7% less cost and 120 million tons (mt) less coal. Alternatively, for greater environmental protection, China could satisfy the same demands at the same cost using 275 mt coal. 27 refs., 6 figs.

  15. Two-sided reflection of Markov-modulated Brownian motion

    NARCIS (Netherlands)

    D'Auria, B.; Ivanovs, J.; Kella, O.; Mandjes, M.

    2012-01-01

    This article considers a Markov-modulated Brownian motion with a two-sided reflection. For this doubly-reflected process we compute the Laplace transform of the stationary distribution, as well as the average loss rates at both barriers. Our approach relies on spectral properties of the matrix polyn

  16. The Two-Sided Mind: Teaching and Suggestopedia.

    Science.gov (United States)

    Bancroft, W. Jane

    This paper explores how Georgi Lozanov's Suggestopedia incorporates elements of modern right-brain research. For example, issues in Linda VerLee Williams's "Teaching for the Two-Sided Mind" that are applicable to Suggestopedia include visual thinking, fantasy, multisensory learning, music, and direct experience. In Robert Ornstein's "The…

  17. Worldsid small female side impact dummy specifications and prototype evaluation

    NARCIS (Netherlands)

    Been, B.W.; Meijer, R.; Bermond, F.; Bortenschlager, K.; Hynd, D.; Martinez, L.; Ferichola, G.

    2007-01-01

    The WorldSID program was set up to develop a new, worldwide acceptable, advanced technology, side impact crash test dummy for improved assessment of injury risk to car occupants in lateral collisions. Following the release of the mid-sized male WorldSID, the development of the small female WorldSID

  18. Supply-Side Interventions and Student Learning in Guatemala

    Science.gov (United States)

    Vasquez, William F.

    2012-01-01

    This paper presents estimates of production functions of reading and mathematics test scores to assess the effects of supply-side interventions, such as the provision of a community-based school management programme, bilingual education and multigrade teaching, on student learning in Guatemala. The efficiency and consistency of the estimates is…

  19. Eubiosis and dysbiosis: the two sides of the microbiota.

    Science.gov (United States)

    Iebba, Valerio; Totino, Valentina; Gagliardi, Antonella; Santangelo, Floriana; Cacciotti, Fatima; Trancassini, Maria; Mancini, Carlo; Cicerone, Clelia; Corazziari, Enrico; Pantanella, Fabrizio; Schippa, Serena

    2016-01-01

    The microbial ecosystem of the gastrointestinal tract is characterized by a great number of microbial species living in balance by adopting mutualistic strategies. The eubiosis/dysbiosis condition of the gut microbiota strongly influences our healthy and disease status. This review briefly describes microbiota composition and functions, to then focus on eubiosis and dysbiosis status: the two sides of the microbiota.

  20. Acute and long-term psychiatric side effects of mefloquine

    DEFF Research Database (Denmark)

    Ringqvist, Asa; Bech, Per; Glenthøj, Birte

    2014-01-01

    psychiatric side effects were retrospectively assessed using the SCL-90-R and questions based on Present State Examination (PSE). Subjects reporting suspected psychotic states were contacted for a personal PSE interview. Electronic records of psychiatric hospitalizations and diagnoses were cross-checked. Long...

  1. Single-Sided Natural Ventilation through a Velux Roof Window

    DEFF Research Database (Denmark)

    Li, Zhigang; Nielsen, Peter Vilhelm; Fransson, J.

    2004-01-01

    This paper investigates the single-sided natural ventilation through a VELUX centre pivot roof window under natural weather conditions. The aim of the investigation is to develop an empirical formulation for air flow rate through a roof window based on CFD and tracer gas decay measurement methods...

  2. Photoinduced Circular Anisotropy in Side-Chain Azobenzene Polyesters

    DEFF Research Database (Denmark)

    Nikolova, L.; Todorov, T.; Ivanov, M.;

    1997-01-01

    We report for the first time the inducing of large circular anisotropy in previously unoriented films of side-chain azobenzene polyesters on illumination with circularly polarized light at a wavelength of 488 nm. The circular dichroism and optical activity are measured simultaneously in real time...

  3. a Study on Impact Analysis of Side Kick in Taekwondo

    Science.gov (United States)

    Lee, Jung-Hyun; Lee, Young-Shin; Han, Kyu-Hyun

    Taekwondo is a martial art form and sport that uses the hands and feet for attack and defense. Taekwondo basic motion is composed of the breaking, competition and poomsea motions. The side kick is one of the most important breaking motions. The side kick with the front foot can be made in two steps. In the first step, the front foot is extended forward from the back stance free-fighting position. For the second step, the rear foot is followed simultaneously. Then, the side kick is executed while the entire body weight rests on the rear foot. In this paper, the impact analysis on a human model for kicking posture was carried out. The ADAMS/LifeMOD used numerical modeling and simulation for the side kick. The numerical human models for assailant and opponent in competition motion were developed. The maximum impact force on the human body was obtained by experiment and was applied to impact simulation. As a result, the impact displacement and velocity of the numerical human model were investigated.

  4. Imaging findings in right-sided diverticulitis in a child

    Energy Technology Data Exchange (ETDEWEB)

    Bogue, Conor O.; Mann, Erika H. [University of Toronto, Department of Diagnostic Imaging, Hospital for Sick Children, Toronto (Canada)

    2008-10-15

    We report the imaging findings in a case of acute right-sided diverticulitis in a 13-year-old boy. Based on this diagnosis the patient was successfully treated conservatively with intravenous antibiotics. This entity should be considered in patients with right lower quadrant pain and a sonographically normal appendix, particularly in those of Asian or Pacific descent. (orig.)

  5. Synthesis of Bisphenols Carrying Long Hydrocarbon Side Chains

    Institute of Scientific and Technical Information of China (English)

    XU Jing-zhe; JIANG Nan-zhe; ZHANG Jian; JIANG Ri-shan

    2005-01-01

    Bisphenols containing long aliphatic hydrocarbon side chains were synthesized by the condensation of phenol with aldehyde or ketone in the presence of heteropolyacid. Their structures were characterized by IR, 1H NMR, 13C NMR and element analysis. The experiment results show that when heteropolyacid was used as a catalyst, these bisphenols were obtained in high selectivity and high yields.

  6. A Frame Nucleus on a Two-side Prequantale

    Institute of Scientific and Technical Information of China (English)

    XUShao-xian; WANGShun-qin; MAFei-fei

    2004-01-01

    In this paper, a Frame nucleus and prime elements in a Prequantale are defined. The concrete structure of a Frame prequantic quotient is considered, and the relation between the half-prime element and the Frame nucleus in a two-side Prequantale are obtained.

  7. Optimization of Circular Side Door Beam for Crashworthiness Analysis

    Directory of Open Access Journals (Sweden)

    Raja Sharmi Raja Husin

    2012-01-01

    Full Text Available Structural optimization related to crashworthiness and energy absorption capability is particularly importance to the automotive industry. The optimization involves highly nonlinear computational analysis and design with many material and structure parameters. This paper presents a crashworthiness design of the circular side door beam which attach to the side door structures. The response surface method (RSM is utilized to formulate the complex crashworthiness design problem in the case of optimization. In this study, side door beam will be optimized. The beams in circular shape were studied and compared. The focus is on finding an optimum cross-section shape of the beam in order to improve the energy absorption character.  An optimization problem is formulated to find the maximum energy absorbed with the maximum peak load as a constraint, the shape of the beam cross section and the thickness as variable. The structure optimum design and simulation analysis of automobile side-door beam was carried out by using Finite Element (FE method.

  8. Neck forces and moments and head accelerations in side impact

    NARCIS (Netherlands)

    Yoganandan, N.; Pintar, F.A.; Maiman, D.J.; Philippens, M.M.G.M.; Wismans, J.S.H.M.

    2009-01-01

    Objectives: Although side-impact sled studies have investigated chest, abdomen, and pelvic injury mechanics, determination of head accelerations and the associated neck forces and moments is very limited. The purpose of the present study was therefore to determine the temporal forces and moments at

  9. Synthesis of macrocyclic lactones with methoxysulfonyl side chain

    Institute of Scientific and Technical Information of China (English)

    Chuan Jin Hou; Xiao Mei Liang; Jing Ping Wu; Dao Quan Wang

    2008-01-01

    Two representative macrocyclic lactones with methoxysulfonyl side chain (5a and 5b) were synthesized employing Michael addition with acrolein and ring enlargement as the key steps,starting from potassium a-oxocycloalkylsulfonates (1) in total yields of 45 and 57%,respectively.

  10. Handedness and dominant side of symptoms in Parkinson's disease

    NARCIS (Netherlands)

    van der Hoorn, Anouk; Bartels, Anna L.; Leenders, Klaus L.; de Jong, Bauke M.

    2011-01-01

    The aim of this retrospective study was to assess the presence of a possible association between handedness and the side of symptom dominance in 963 patients with Parkinson's disease (PD). In only 287 patients the hand dominance was registered. Out of 254 right-handed patients, 158 (62%) had a right

  11. Construct Validity of Measures of Becker's Side Bet Theory.

    Science.gov (United States)

    Shore, Lynn M.; Tetrick, Lois E.; Shore, Ted H.; Barksdale, Kevin

    2000-01-01

    Becker's side bet theory (remaining in a job because of perceived costs of leaving) was tested using data from 327 working business students. Three factors were most consistent with the theory: bureaucratic organization, nonwork-related concerns, and adjustment to social position. Attachment to the organization was significantly linked to tangible…

  12. Right-sided aortic arch with Kommerell′s aneurysm

    Directory of Open Access Journals (Sweden)

    Sanjay Orathi Patangi

    2014-01-01

    Full Text Available We present a case report of a 55-year-old lady who presented with progressive dysphagia and was diagnosed with a Kommerell′s aneurysm and a right-sided aortic arch. This case report outlines our management strategy and the challenges encountered during the perioperative period in a patient with this rare anomaly.

  13. Gecko-inspired bidirectional double-sided adhesives.

    Science.gov (United States)

    Wang, Zhengzhi; Gu, Ping; Wu, Xiaoping

    2014-05-14

    A new concept of gecko-inspired double-sided adhesives (DSAs) is presented. The DSAs, constructed by dual-angled (i.e. angled base and angled tip) micro-pillars on both sides of the backplane substrate, are fabricated by combinations of angled etching, mould replication, tip modification, and curing bonding. Two types of DSA, symmetric and antisymmetric (i.e. pillars are patterned symmetrically or antisymmetrically relative to the backplane), are fabricated and studied in comparison with the single-sided adhesive (SSA) counterparts through both non-conformal and conformal tests. Results indicate that the DSAs show controllable and bidirectional adhesion. Combination of the two pillar-layers can either amplify (for the antisymmetric DSA, providing a remarkable and durable adhesion capacity of 25.8 ± 2.8 N cm⁻² and a high anisotropy ratio of ∼8) or counteract (for the symmetric DSA, generating almost isotropic adhesion) the adhesion capacity and anisotropic level of one SSA (capacity of 16.2 ± 1.7 N cm⁻² and anisotropy ratio of ∼6). We demonstrate that these two DSAs can be utilized as a facile fastener for two individual objects and a small-scale delivery setup, respectively, complementing the functionality of the commonly studied SSA. As such, the double-sided patterning is believed to be a new branch in the further development of biomimetic dry adhesives.

  14. $xy$ Position Reconstruction in DarkSide-50

    Energy Technology Data Exchange (ETDEWEB)

    Brodsky, Jason Philip [Princeton Univ., NJ (United States)

    2015-01-01

    The DarkSide-50 experiment seeks to directly detect dark matter in a liquid argon time projection chamber. In this dissertation, I present an algorithm of my design that determines the position of particle interactions with the liquid argon. This position reconstruction algorithm will be used by DarkSide-50 to reject backgrounds, particularly backgrounds from radioactive elements on the detector surface. The position reconstruction algorithm functions by constructing light response functions (LRFs) that map locations in the detector to the expected distribution of signal in DarkSide-50's 38 photomultiplier tubes. Accurate LRFs cannot be produced by simulations of DarkSide-50's optics because such simulations are known to be awed. Instead, this algorithm constructs LRFs using an iterative process driven by data. Initial, awed LRFs are produced using simulated events but then used to produce new LRFs from data events. Multiple generations of LRFs are created from data with each generation driven to better satisfy a known feature of the detector: the dominant argon-39 background is uniformly distributed. I also discuss a method of discriminating against surface background as an alternative to the common approach of ducialization. This method considers the di erence in goodnessof- t between the best- t reconstructed position and the best- t position at the detector's surface. I conclude by presenting results on the performance and validity of this algorithm, including some discussion of reconstruction errors.

  15. Photoorientation of a liquid crystalline polyester with azobenzene side groups

    DEFF Research Database (Denmark)

    Zebger, I; Rutloh, M; Hoffmann, U

    2002-01-01

    . This model polymer is characterized by liquid crystallinity (g 24 S-X 26 S-A 34 n 47 i) and a strong aggregation tendency. The photoorientation is cooperative, i.e., the orientation of the photochromic side group induces the alignment of the ester unit (which is a part of the main-chain) and both methylene...

  16. Supply-side collaboration for energy-efficient renovations

    NARCIS (Netherlands)

    Straub, A.; Mlecnik, E.

    2015-01-01

    The supply side for nearly zero energy building (nZEB) renovation of owner-occupied single-family houses in Europe is suffering from a severe image problem of lack of knowledge and trust, inefficient construction processes, insufficient quality assurance and communication difficulties with home-owne

  17. Making "cents" of the business side of nurse practitioner practice.

    Science.gov (United States)

    Luster-Tucker, AtNena

    2016-03-15

    Nurse practitioners produce excellent patient outcomes and should be allowed to practice to the full extent of their education and training. In addition to clinical skills, nurse practitioners need to understand the business side of practice in order to ensure fair and equitable compensation.

  18. Modeling Supermarket Refrigeration Systems for Demand-Side Management

    DEFF Research Database (Denmark)

    Shafiei, Seyed Ehsan; Rasmussen, Henrik; Stoustrup, Jakob

    2013-01-01

    fidelity. Moreover a simulation benchmark is introduced based on the produced model for demand-side management in smart grid. Finally, a potential application of the proposed benchmark in direct control of the power/energy consumption is presented by a simple simulation example....

  19. Numerical modeling of secondary side thermohydraulics of horizontal steam generator

    Energy Technology Data Exchange (ETDEWEB)

    Melikhov, V.I.; Melikhov, O.I.; Nigmatulin, B.I. [Research and Engineering Centre of LWR Nuclear Plants Safety, Moscow (Russian Federation)

    1995-12-31

    A mathematical model for the transient three-dimensional secondary side thermal hydraulics of the horizontal steam generator has been developed. The calculations of the steam generator PGV-1000 and PGV-4 nominal regimes and comparison of numerical and experimental results have been carried out. 7 refs.

  20. Black carbon: The reverse of its dark side

    NARCIS (Netherlands)

    Koelmans, A.A.; Jonker, M.T.O.; Cornelissen, G.; Bucheli, T.D.; Noort, van P.C.M.; Gustafsson, O.

    2006-01-01

    The emission of black carbon is known to cause major environmental problems. Black carbon particles contribute to global warming, carry carcinogenic compounds and cause serious health risks. Here, we show another side of the coin. We review evidence that black carbon may strongly reduce the risk pos

  1. Locomotion in Stroke Subjects: Interactions between Unaffected and Affected Sides

    Science.gov (United States)

    Kloter, Evelyne; Wirz, Markus; Dietz, Volker

    2011-01-01

    The aim of this study was to evaluate the sensorimotor interactions between unaffected and affected sides of post-stroke subjects during locomotion. In healthy subjects, stimulation of the tibial nerve during the mid-stance phase is followed by electromyography responses not only in the ipsilateral tibialis anterior, but also in the proximal arm…

  2. The Future of Innovation - Beware of the Dark Side

    DEFF Research Database (Denmark)

    2011-01-01

    of success). We all get excited by the potential and possibilities innovation seems to offer. The presentation will ask whether there might be a dark side of innovation. We certainly need to think about innovation, a lot. But perhaps not quite as we know it, and the way we are used to. The presentation...

  3. Influence of cutting conditions on chip side curl

    DEFF Research Database (Denmark)

    De Chiffre, Leonardo

    2004-01-01

    The paper describes the influence of local variations of contact length, cutting speed and material constraint, showing the effect of lubrication, on the side curl of the chip. The following examples are illustrated by experiments: cutting of a tube vs. cutting of a bar; cutting using a tool with...

  4. Side Effects of HIV Medicines: HIV and Diabetes

    Science.gov (United States)

    Side Effects of HIV Medicines HIV and Diabetes (Last updated 11/17/2016; last reviewed 11/17/2016) Key Points Diabetes is a disease in which levels of blood glucose (also called blood sugar) are too high. Glucose comes from the ...

  5. Side Effects of HIV Medicines: HIV and Osteoporosis

    Science.gov (United States)

    Side Effects of HIV Medicines HIV and Osteoporosis (Last updated 11/17/2016; last reviewed 11/17/2016) Key Points Osteoporosis is a disease that causes bones to become weak and easy to break. Osteoporosis increases the risk of fractures of ...

  6. Existence theorems for differential inclusions with nonconvex right hand side

    Directory of Open Access Journals (Sweden)

    Nikolaos S. Papageorgiou

    1986-01-01

    Full Text Available In this paper we prove some new existence theorems for differential inclusions with a nonconvex right hand side, which is lower semicontinuous or continuous in the state variable, measurable in the time variable and takes values in a finite or infinite dimensional separable Banach space.

  7. Tamoxifen treatment and gynecologic side effects : A review

    NARCIS (Netherlands)

    Mourits, MJE; De Vries, EGE; Willemse, PHB; Ten Hoor, KA; Hollema, H; Van der Zee, AGJ

    2001-01-01

    Objective: To review the literature on tamoxifen side effects on the female genital tract and psychosexual function in premenopausal and postmenopausal women. Data Sources: We used the English-language literature in MEDLINE and reference lists from selected articles. Search terms included: "tamoxife

  8. The Semiosis of "Side Effects" in Genetic Interventions.

    Science.gov (United States)

    Affifi, Ramsey

    2016-01-01

    Genetic interventions, which include transgenic engineering, gene editing, and other forms of genome modification aimed at altering the information "in" the genetic code, are rapidly increasing in power and scale. Biosemiotics offers unique tools for understanding the nature, risks, scope, and prospects of such technologies, though few in the community have turned their attention specifically in this direction. Bruni (2003, 2008) is an important exception. In this paper, I examine how we frame the concept of "side effects" that result from genetic interventions and how the concept stands up to current perspectives of the role of organism activity in development. I propose that once the role of living systems in constructing and modifying the informational value of their various developmental resources is taken into account, the concept of a "side effect" will need to be significantly revised. Far from merely a disturbance brought about in a senseless albeit complex system, a biosemiotic view would take "side effects" as at least sometimes the organism's active re-organization in order to accommodate or make use of novelty. This insight is nascent in the work of developmental plasticity and niche construction theory (West-Eberhard 2003; Odling-Smee et al. 2003), but it is brought into sharper focus by the explicitly interpretive perspective offered by biosemiotics. Understanding the "side effects" of genetic interventions depends in part on being able to articulate when and where unexpected consequences are a result of semiotic activity at various levels within the system. While a semiotic interpretation of "side effects" puts into question the naive attitude that would see all unintended side effects as indications of disturbance in system functionality, it certainly does not imply that such side effects are of no concern for the viability of the organisms in the system. As we shall see, the fact that such interventions do not respect the translation of information

  9. Server-side Filtering and Aggregation within a Distributed Environment

    Science.gov (United States)

    Currey, J. C.; Bartle, A.

    2015-12-01

    Intercalibration, validation, and data mining use cases require more efficient access to the massive volumes of observation data distributed across multiple agency data centers. The traditional paradigm of downloading large volumes of data to a centralized server or desktop computer for analysis is no longer viable. More analysis should be performed within the host data centers using server-side functions. Many comparative analysis tasks require far less than 1% of the available observation data. The Multi-Instrument Intercalibration (MIIC) Framework provides web services to find, match, filter, and aggregate multi-instrument observation data. Matching measurements from separate spacecraft in time, location, wavelength, and viewing geometry is a difficult task especially when data are distributed across multiple agency data centers. Event prediction services identify near coincident measurements with matched viewing geometries near orbit crossings using complex orbit propagation and spherical geometry calculations. The number and duration of event opportunities depend on orbit inclinations, altitude differences, and requested viewing conditions (e.g., day/night). Event observation information is passed to remote server-side functions to retrieve matched data. Data may be gridded, spatially convolved onto instantaneous field-of-views, or spectrally resampled or convolved. Narrowband instruments are routinely compared to hyperspectal instruments such as AIRS and CRIS using relative spectral response (RSR) functions. Spectral convolution within server-side functions significantly reduces the amount of hyperspectral data needed by the client. This combination of intelligent selection and server-side processing significantly reduces network traffic and data to process on local servers. OPeNDAP is a mature networking middleware already deployed at many of the Earth science data centers. Custom OPeNDAP server-side functions that provide filtering, histogram analysis (1D

  10. Coupling Motion and Energy Harvesting of Two Side-by-Side Flexible Plates in a 3D Uniform Flow

    Directory of Open Access Journals (Sweden)

    Dibo Dong

    2016-05-01

    Full Text Available The fluid-structure interaction problems of two side-by-side flexible plates with a finite aspect ratio in a three-dimensional (3D uniform flow are numerically studied. The plates’ motions are entirely passive under the force of surrounding fluid. By changing the aspect ratio and transverse distance, the coupling motions, drag force and energy capture performance are analyzed. The mechanisms underlying the plates’ motion and flow characteristics are discussed systematically. The adopted algorithm is verified and validated by the simulation of flow past a square flexible plate. The results show that the plate’s passive flapping behavior contains transverse and spanwise deformation, and the flapping amplitude is proportional to the aspect ratio. In the side-by-side configuration, three distinct coupling modes of the plates’ motion are identified, including single-plate mode, symmetrical flapping mode and decoupled mode. The plate with a lower aspect ratio may suffer less drag force and capture less bending energy than in the isolated situation. The optimized selection for obtaining higher energy conversion efficiency is the plate flapping in single-plate mode, especially the plate with a higher aspect ratio. The findings of this work provide several new physical insights into the understanding of fish schooling and are expected to inspire the developments of underwater robots or energy harvesters.

  11. Influence of the side-by-side arrangement on the performance of a small Savonius wind turbine

    Directory of Open Access Journals (Sweden)

    Jang Choon-Man

    2016-01-01

    Full Text Available Scaled-down Savonius turbine rotors arrayed side-by-side are introduced to analyze the effects of design parameters on the performance between turbine rotors. Unsteady flow simulation and experimental measurement have been performed to compare turbine performance and validate the numerical simulation of the turbine rotor. Commercial code, SC/Tetra, which uses an unstructured grid system, has been used to solve the three-dimensional unsteady Reynolds-averaged Navier–Stokes equations. Single turbine rotors and two turbine rotors arrayed side-by-side were numerically analyzed. The distance between rotor tips is 0.5 times the rotor diameter. Throughout the numerical simulation, the power coefficient obtained by the time-averaged result of unsteady flow simulation was found to be in good agreement with the experimental result. A discussion on the design parameters using both a single and arrayed turbine rotors is presented based on the results of the unsteady flow simulation, including the flow field, power coefficient, velocity and vorticity contours.

  12. Control mechanism and technique of floor heave with reinforcing solid coal side and floor corner in gob-side coal entry retaining

    Institute of Scientific and Technical Information of China (English)

    Chen; Yong; Bai; Jianbiao; Yan; Shuai; Xu; Ying; Wang; Xiangyu; Ma; Shuqi

    2012-01-01

    Floor heave is the most common convergence in gob-side entry retaining.The paper analyzes the form,process and characteristics of gob-side entry retaining with the comprehensive methods of theoretical analysis,numerical simulation and the field trial.Research results present that bending and folding floor heave is the main factor in the stage of the first panel mining;squeezing and fluidity floor heave plays a great role in the stable stage of gob-side entry retaining;the combination of the former two factors affects mainly the stage of the second mining ahead;abutment pressure is a fundamental contribution to the serious floor heave of gob-side entry retaining,and sides corners of solid coal body are key part in the case of floor heave controlling of gob-side entry retaining.Floor heave of gob-side entry retaining can be significantly controlled by reinforcing sides and corners of solid coal body,and influence rules on the floor heave of gob side entry retaining of sides supporting strength and the bottom bolt orientation in solid coal side are obtained.Research results have been successfully applied in gob-side entry retaining of G20-F23070 face haulage roadway in #2 coal mine of Pingmei Group,and the field observation shows that the proposed technique is an effective way in controlling the floor heave of gob-side entry retaining.

  13. Control mechanism and technique of floor heave with reinforcing solid coal side and floor corner in gob-side coal entry retaining

    Institute of Scientific and Technical Information of China (English)

    Chen Yong; Bai Jianbiao; Yan Shuai; Xu Ying; Wang Xiangyu; Ma Shuqi

    2012-01-01

    Floor heave is the most common convergence in gob-side entry retaining.The paper analyzes the form,process and characteristics of gob-side entry retaining with the comprehensive methods of theoretical analysis,numerical simulation and the field trial.Research results present that bending and folding floor heave is the main factor in the stage of the first panel mining; squeezing and fluidity floor heave plays a great role in the stable stage of gob-side entry retaining; the combination of the former two factors affects mainly the stage of the second mining ahead; abutment pressure is a fundamental contribution to the serious floor heave of gob-side entry retaining,and sides comers of solid coal body are key part in the case of floor heave controlling of gob-side entry retaining.Floor heave of gob-side entry retaining can be significantly controlled by reinforcing sides and comers of solid coal body,and influence rules on the floor heave of gob side entry retaining of sides supporting strength and the bottom bolt orientation in solid coal side are obtained.Research results have been successfully applied in gob-side entry retaining of G20-F23070 face haulage roadway in #2 coal mine of Pingmei Group,and the field observation shows that the proposed technique is an effective way in controlling the floor heave of gob-side entry retaining.

  14. Detached Eddy Simulation of Flap Side-Edge Flow

    Science.gov (United States)

    Balakrishnan, Shankar K.; Shariff, Karim R.

    2016-01-01

    Detached Eddy Simulation (DES) of flap side-edge flow was performed with a wing and half-span flap configuration used in previous experimental and numerical studies. The focus of the study is the unsteady flow features responsible for the production of far-field noise. The simulation was performed at a Reynolds number (based on the main wing chord) of 3.7 million. Reynolds Averaged Navier-Stokes (RANS) simulations were performed as a precursor to the DES. The results of these precursor simulations match previous experimental and RANS results closely. Although the present DES simulations have not reached statistical stationary yet, some unsteady features of the developing flap side-edge flowfield are presented. In the final paper it is expected that statistically stationary results will be presented including comparisons of surface pressure spectra with experimental data.

  15. A Double-Sided Linear Primary Permanent Magnet Vernier Machine

    Directory of Open Access Journals (Sweden)

    Yi Du

    2015-01-01

    Full Text Available The purpose of this paper is to present a new double-sided linear primary permanent magnet (PM vernier (DSLPPMV machine, which can offer high thrust force, low detent force, and improved power factor. Both PMs and windings of the proposed machine are on the short translator, while the long stator is designed as a double-sided simple iron core with salient teeth so that it is very robust to transmit high thrust force. The key of this new machine is the introduction of double stator and the elimination of translator yoke, so that the inductance and the volume of the machine can be reduced. Hence, the proposed machine offers improved power factor and thrust force density. The electromagnetic performances of the proposed machine are analyzed including flux, no-load EMF, thrust force density, and inductance. Based on using the finite element analysis, the characteristics and performances of the proposed machine are assessed.

  16. The higher you climb: Dark side personality and job level.

    Science.gov (United States)

    Gøtzsche-Astrup, Oluf; Jakobsen, Joan; Furnham, Adrian

    2016-12-01

    The purpose of this study was to explore the idea that there are dark side personality differences in the profiles of people at different levels in organizations. This study replicates and extends existing leadership research by focusing on self-defeating behavioral tendencies. A Danish consultancy provided data on 264 adults based on assessment reports. This paper explored linear and quadratic relationships between personality and de facto job level. More senior managers scored high on Cluster B/Moving Against Others scales of Bold, Colorful and Imaginative, and low on Cautious and Dutiful. These Danish data are compared to data from Great Britain and New Zealand which show very similar findings. Practice should take into account that dark side personality traits associated with an assertive, sometimes hostile, interpersonal orientation, predict leadership level up to a point.

  17. Suspected side effects to the quadrivalent human papilloma vaccine

    DEFF Research Database (Denmark)

    Brinth, Louise; Theibel, Ann Cathrine; Pors, Kirsten;

    2015-01-01

    system dysfunction have been described as suspected side effects to the Q-HPV vaccine. METHODS: We present a description of suspected side effects to the Q-HPV vaccine in 53 patients referred to our Syncope Unit for tilt table test and evaluation of autonomic nervous system function. RESULTS: All......INTRODUCTION: The quadrivalent vaccine that protects against human papilloma virus types 6, 11, 16 and 18 (Q-HPV vaccine, Gardasil) was included into the Danish childhood vaccination programme in 2009. During the past years, a collection of symptoms primarily consistent with sympathetic nervous...... consistency in the reported symptoms as well as between our findings and those described by others. Our findings neither confirm nor dismiss a causal link to the Q-HPV vaccine, but they suggest that further research is urgently warranted to clarify the pathophysiology behind the symptoms experienced...

  18. A double-sided linear primary permanent magnet vernier machine.

    Science.gov (United States)

    Du, Yi; Zou, Chunhua; Liu, Xianxing

    2015-01-01

    The purpose of this paper is to present a new double-sided linear primary permanent magnet (PM) vernier (DSLPPMV) machine, which can offer high thrust force, low detent force, and improved power factor. Both PMs and windings of the proposed machine are on the short translator, while the long stator is designed as a double-sided simple iron core with salient teeth so that it is very robust to transmit high thrust force. The key of this new machine is the introduction of double stator and the elimination of translator yoke, so that the inductance and the volume of the machine can be reduced. Hence, the proposed machine offers improved power factor and thrust force density. The electromagnetic performances of the proposed machine are analyzed including flux, no-load EMF, thrust force density, and inductance. Based on using the finite element analysis, the characteristics and performances of the proposed machine are assessed.

  19. Suspected side effects to the quadrivalent human papilloma vaccine

    DEFF Research Database (Denmark)

    Brinth, Louise; Theibel, Ann Cathrine; Pors, Kirsten

    2015-01-01

    INTRODUCTION: The quadrivalent vaccine that protects against human papilloma virus types 6, 11, 16 and 18 (Q-HPV vaccine, Gardasil) was included into the Danish childhood vaccination programme in 2009. During the past years, a collection of symptoms primarily consistent with sympathetic nervous...... system dysfunction have been described as suspected side effects to the Q-HPV vaccine. METHODS: We present a description of suspected side effects to the Q-HPV vaccine in 53 patients referred to our Syncope Unit for tilt table test and evaluation of autonomic nervous system function. RESULTS: All...... consistency in the reported symptoms as well as between our findings and those described by others. Our findings neither confirm nor dismiss a causal link to the Q-HPV vaccine, but they suggest that further research is urgently warranted to clarify the pathophysiology behind the symptoms experienced...

  20. The higher you climb: Dark side personality and job level

    DEFF Research Database (Denmark)

    Gøtzsche-Astrup, Oluf; Jakobsen, Joan; Furnham, Adrian

    2016-01-01

    provided data on 264 adults based on assessment reports. This paper explored linear and quadratic relationships between personality and de facto job level. More senior managers scored high on Cluster B/Moving Against Others scales of Bold, Colorful and Imaginative, and low on Cautious and Dutiful......The purpose of this study was to explore the idea that there are dark side personality differences in the profiles of people at different levels in organizations. This study replicates and extends existing leadership research by focusing on self-defeating behavioral tendencies. A Danish consultancy....... These Danish data are compared to data from Great Britain and New Zealand which show very similar findings. Practice should take into account that dark side personality traits associated with an assertive, sometimes hostile, interpersonal orientation, predict leadership level up to a point....

  1. Facial electroneurography on the contralateral side in unilateral Bell's palsy.

    Science.gov (United States)

    Psillas, G; Daniilidis, J

    2002-07-01

    In this study, ten patients who exhibited severe unilateral Bell's palsy of the House-Brackmann grade V underwent facial electroneurography (ENoG) on the contralateral, healthy side. Serial ENoG was conducted in seven consecutive sessions within 6 months at a given current intensity level of stimulation. According to our results, all the patients presented a rise in the maximum compound-action potential (MCAP) amplitude on the healthy side within 20 to 45 days from the onset of the palsy and shortly after the onset of the recovery of the facial function. This was attributed to the central contralateral compensatory process, which restores balanced facial function. Based on our data, a hypothetical model is shown, which demonstrates the clinical course of the contralateral MCAP values and reflects the plasticity effect of the central nervous system after the onset of Bell's palsy.

  2. Drug target identification using side-effect similarity

    DEFF Research Database (Denmark)

    Campillos, Monica; Kuhn, Michael; Gavin, Anne-Claude;

    2008-01-01

    Targets for drugs have so far been predicted on the basis of molecular or cellular features, for example, by exploiting similarity in chemical structure or in activity across cell lines. We used phenotypic side-effect similarities to infer whether two drugs share a target. Applied to 746 marketed...... drugs, a network of 1018 side effect-driven drug-drug relations became apparent, 261 of which are formed by chemically dissimilar drugs from different therapeutic indications. We experimentally tested 20 of these unexpected drug-drug relations and validated 13 implied drug-target relations by in vitro...... binding assays, of which 11 reveal inhibition constants equal to less than 10 micromolar. Nine of these were tested and confirmed in cell assays, documenting the feasibility of using phenotypic information to infer molecular interactions and hinting at new uses of marketed drugs....

  3. Application Neutrality and a Paradox of Side Payments

    CERN Document Server

    Altman, Eitan; Kesidis, George

    2010-01-01

    The ongoing debate over "net neutrality" covers a broad set of issues related to the regulation of public networks. This paper contains two separate contributions: (a) an extension of the quadratic-utility framework we proposed in a previous paper to study the impact of side payments in a system involving pluralities of access and content providers; and (b) a variation of this model to deal with the question of application neutrality. Our analysis of the generalized framework (a) reveals an interesting "paradox" that did not occur with monopolistic players: side payments handicap the providers who perceive them. Application neutrality (b) refers to price discrimination: ISPs charging consumers different fees depending on their use of the network (web surfing, VoIP, file sharing, etc.). We analyze the consequences of such discrimination for a simple two-application setting.

  4. Adaptive-Rate Compressive Sensing Using Side Information.

    Science.gov (United States)

    Warnell, Garrett; Bhattacharya, Sourabh; Chellappa, Rama; Başar, Tamer

    2015-11-01

    We provide two novel adaptive-rate compressive sensing (CS) strategies for sparse, time-varying signals using side information. The first method uses extra cross-validation measurements, and the second one exploits extra low-resolution measurements. Unlike the majority of current CS techniques, we do not assume that we know an upper bound on the number of significant coefficients that comprises the images in the video sequence. Instead, we use the side information to predict the number of significant coefficients in the signal at the next time instant. We develop our techniques in the specific context of background subtraction using a spatially multiplexing CS camera such as the single-pixel camera. For each image in the video sequence, the proposed techniques specify a fixed number of CS measurements to acquire and adjust this quantity from image to image. We experimentally validate the proposed methods on real surveillance video sequences.

  5. Persisting asymmetries of vision after right side lesions

    DEFF Research Database (Denmark)

    Habekost, Thomas; Rostrup, Egill

    2006-01-01

    report experiments were used to estimate psychophysical parameters related to visual capacity and attentional weighting in 26 patients with stroke in the right side of the brain. The results were analyzed using Bundesen's Theory of Visual Attention (TVA [Bundesen, C. (1990). A theory of visual attention......-1188]. Lesions were examined by MR scanning and analyzed statistically. Two main types of deficit were found. The first type was related to perception of unilateral displays, where most patients showed left side reductions of visual processing speed. This visual asymmetry correlated with injury to the putamen...... and surrounding white matter. The second deficit type occurred with bilateral displays, which increased the visual asymmetry (extinction effect) for most patients with large cortico-subcortical lesions, but rarely for patients with focal lesions. However, in a single case with pulvinar damage, visual asymmetry...

  6. The human dark side: evolutionary psychology and original sin.

    Science.gov (United States)

    Lee, Joseph; Theol, M

    2014-04-01

    Human nature has a dark side, something important to religions. Evolutionary psychology has been used to illuminate the human shadow side, although as a discipline it has attracted criticism. This article seeks to examine the evolutionary psychology's understanding of human nature and to propose an unexpected dialog with an enduring account of human evil known as original sin. Two cases are briefly considered: murder and rape. To further the exchange, numerous theoretical and methodological criticisms and replies of evolutionary psychology are explored jointly with original sin. Evolutionary psychology can partner with original sin since they share some theoretical likenesses and together they offer insights into the nature of what it means to be human.

  7. Photophysical characteristics of polyaniline with photochromic azobenzene side groups

    Institute of Scientific and Technical Information of China (English)

    Feng Wei; Huang Kun; Wan Mei-Xiang

    2005-01-01

    Photochromic characteristics and optical molecular reorientation in conducting polymer such as polyaniline derivatives containing photochromic azobenzene moieties (PAPNPAPOA) in side chain are studied. Changes in the UV-vis absorption, refractive index, thickness, contact angle and morphology of these films after irradiation of a linearly polarized light with a wavelength of 365nm are measured. The trans-cis isomerization of PAPNPAPOA is proved irreversible even after withdrawing the UV light for a long time. That the structure of main-chain attends by the trans-cis isomerization of side-chain is confirmed by the absorption and the solution colour during the UV irradiation. These effects are discussed by taking the trans-cis isomerization of azobenzene into consideration.

  8. Two-Sided Gravitational Mirror: Sealing off Curvature Singularities

    OpenAIRE

    Davidson, Aharon; Yellin, Ben

    2011-01-01

    A gravitational mirror is a non-singular finite redshift surface which bounces all incident null geodesics. While a white mirror (outward bouncing) resembles 't Hooft's brick wall, a black mirror (inward bouncing) offers a novel mechanism for sealing off curvature singularities. The geometry underlying a two-sided mirror is characterized by a single signature change, to be contrasted with the signature flip which governs the black hole geometry. To demonstrate the phenomenon analytically, we ...

  9. Efeitos colaterais do metilfenidato Side effects of methylphenidate

    Directory of Open Access Journals (Sweden)

    Giuseppe Pastura

    2004-01-01

    Full Text Available OBJETIVOS: Revisar os principais efeitos colaterais do metilfenidato, em curto e longo prazos, no tratamento de crianças com Transtorno do Déficit de Atenção (TDAH. FONTES DE DADOS: Revisão de literatura nos últimos doze anos através de pesquisa no Medline e Lilacs. RESULTADOS: Dentre os efeitos colaterais que surgem em curto prazo, prevalecem a redução de apetite, insônia, cefaléia e dor abdominal, sendo a maioria autolimitada, dose-dependente e de média intensidade. Dentre aqueles em longo prazo, são descritas alterações discretas de pressão arterial e freqüência cardíaca e uma possível discreta diminuição da estatura. O abuso e a dependência ao medicamento são observados muito raramente. CONCLUSÕES: O perfil de efeitos colaterais do metilfenidato é seguro, não parecendo justificar o seu uso constrito no Brasil, ante os benefícios robustos amplamente demonstrados na literatura.OBJECTIVE: To review main short-term and long-term side effects of methylphenidate in the treatment of Attention-Deficit Disorder in children. SOURCE OF DATA: a 12-year review in Medline and Lilacs. RESULTS: Among those side effects showed in the short-term, anorexia, insomnia, headache and abdominal pain are the most common ones, being the majority self-limited, dose-dependent and of medium intensity. Long-term side effects consist of mild blood pressure and heart rate increase and possible light growth suppression effect. Abuse and dependency are very rare. CONCLUSIONS: Methylphenidate side effects profile is safe and does not seem to justify its restricted use in Brazil, considering its solid benefits widely demonstrated in literature.

  10. Side-chain liquid crystalline polyesters for optical information storage

    DEFF Research Database (Denmark)

    Ramanujam, P.S.; Holme, Christian; Hvilsted, Søren

    1996-01-01

    Azobenzene side-chain liquid crystalline polyester structures suitable for permanent optical storage are described. The synthesis and characterization of the polyesters together with differential scanning calorimetry and X-ray investigations are discussed. Optical anisotropic investigations...... and holographic storage in one particular polyester are described in detail and polarized Fourier transform infrared spectroscopic data complementing the optical data are presented. Optical and atomic force microscope investigations point to a laser-induced aggregation as responsible for permanent optical storage....

  11. Unbanked Households: Evidence of Supply-Side Factors

    OpenAIRE

    Matray , Adrien; Celerier , Claire

    2014-01-01

    This paper provides evidence that supply-side factors significantly drive the high share of unbanked households. Using interstate branching deregulation in the U.S. after 1994 as an exogenous shock, the authors show that an increase in bank competition is associated with a large drop in the share of unbanked households. The authors find that the effect is even stronger for populations that are more likely to be rationed by banks, such as black households living in "high racial bias'' states. ...

  12. Review about gabapentin misuse, interactions, contraindications and side effects

    OpenAIRE

    Quintero, Gabriel C.

    2017-01-01

    Gabriel C Quintero Florida State University – Republic of Panama, Clayton, Panama Abstract: The current work is targeted to review the risks of gabapentin misuse, its potential interactions with other drugs, side effects and use contraindications. This review consists of a total of 99 biographical references (from the year 1983 to 2016). A publication search of PubMed was performed from January 1983 to December 2016. It included animal studies, clinical studies, case studies and rev...

  13. Blind river dolphin: first side-swimming cetacean.

    Science.gov (United States)

    Herald, E S; Brownell, R L; Frye, F L; Morris, E J; Evans, W E; Scott, A B

    1969-12-12

    The blind river dolphin (Platanista gangetica), first written about by Pliny the Elder in A.D. 72, was found (10 November 1968) to be the first known side-swimming cetacean. The rudimentary eye lacks the lens, but anatomical evidence suggests that the eye may serve as a light sensor. The underwater sound emissions of this species, although similar to those of the Amazon River dolphin (Inia geoffrensis), appear to be produced constantly.

  14. A Rare Side Effect of Metformin: Metformin-Induced Hepatotoxicity

    OpenAIRE

    2007-01-01

    Metformin is an oral hypoglycemic agent that is commonly used in the treatment of type 2 diabetes mellitus. While metformin-associated metabolic acidosis is a widely recognized side effect of this drug, metformin-induced hepatotoxicity has been rarely reported in the literature. We present herein the case of a 52-year-old male in whom metformin-associated lactic acidosis and metformin-induced hepatotoxicity developed.

  15. Regional renal venous hypertension and left-sided varicocele

    Directory of Open Access Journals (Sweden)

    O. B. Zhukov

    2013-01-01

    Full Text Available One of the most frequent correctable causes of male infertility is a varicocele. The etiology and pathogenesis of varicocele to date is a matter of debate. The aim of our study was to determine the causes and incidence of regional renal hypertension in patients with leftsided varicocele. The study involved 110 patients with left-sided varicocele in age from 18 to 35 years. Algorithm for evaluation of patients with left-sided varicocele included: physical examination, ultrasound with Doppler kidney, basin area left renal vein, aorto-mesenteric portion; the scrotum with a sample Trombetta, phlebography аnd phlebotonometry basin left renal vein and the common iliac vein. Renospermatic reflux was detected in 89 (81 %, ileospermatic 12 (11 % and mixed 9 (8 % patients. Patients with reflux ileospermatic excluded from the study. The 96 patients with left-sided varicocele underwent venography and phlebotonometry in 37 (38.5 % were renal venous hypertension, with 35 of them that it was due to aorto-mesenteric compression, and in 2 cases an anomaly development – annular renal vein. Our data are comparable with the results of other authors. Patients with mesenteric compressed statistically significant reduction in the diameter of renal veins in the aorto-mesenteric portion and increased blood flow in this region, and expand prestenosis left renal vein and reduce flow velocity in this region compared with the group without renal phlebohypertension. Patients with renal phlebohypertension subsequently held shunt types of operations performed in patients with normotension occlusive types of operations. An integrated assessment of patients with left-side allows to make a holistic understanding of the basic mechanisms of disease etiology and select the appropriate type of surgery.

  16. Supply Side Constraints on Export Development in Jamaica

    Directory of Open Access Journals (Sweden)

    Marie Freckleton

    2010-11-01

    Full Text Available Este artículo examina los impedimientos por el lado de la oferta que afectan al desarollo de la exportación en Jamaica. El análisis se basa en un examen de exportadores jamaicanos no tradicionales. Los resultados indican que los exportadores jamaicanos hacen frente a impedimientos significativos por el lado de la oferta incluyendo la falta de acceso a capital, insuficiencia de innovaciones, altos costos energéticos y deficiencias infraestructurales. El artículo concluye que en el caso de los países en vías de desarollo afectados por impedimientos por el lado de la oferta se hace necesario tomar medidas que les permitan la ventaja de acceder a los mercados disponibles. En el caso de Jamaica, las medidas requeridas para aliviar los impedimientos por el lado de la oferta incluyen el establecimiento de instituciones financieras de riesgo, el estímulo de la innovación y el desarrollo de la infraestructura. English: This article examines the supply side constraints affecting export development in Jamaica. The analysis is based on a survey of non-traditional exporters. The results of the survey indicates that Jamaican exporters face significant supply side constraints including lack of access to capital, insufficient innovation, high energy costs and infrastructural deficiencies. The article concludes that in the cases of those developing countries facing binding supply side constraints, measures to relax such constraints are necessary to allow them to take full advantage of available market access. In the case of Jamaica, measures required to relax supply side constraints include establishment of venture capital institutions, stimulation of innovation and upgrading of infrastructure.

  17. [Rare side effects in management of hyperthyroidism. Case report].

    Science.gov (United States)

    Sohár, Gábor; Kovács, Mónika; Györkös, Andrea; Gasztonyi, Beáta

    2016-05-29

    The authors present the case history of a patient suffering from hyperthyroidism. The diagnostic procedures revealed the presence of propylthiouracyl induced vasculitis with renal involvement, that recovered completely after the withdrawal of propylthiouracyl and corticosteroid treatment. Thereafter, the patient was treated with thiamasol, that caused agranulocytosis with fever. After transient litium carbonate therapy a succesful thyreoidectomy was performed. Cumulative serious side effects of antithyroid drugs are rare. This case highlights some of the challenges and complications encountered in the management of hyperthyroidism.

  18. Single sided tomography of extremely large dense objects

    Energy Technology Data Exchange (ETDEWEB)

    Thoe, R.S.

    1993-03-24

    One can envision many circumstances where radiography could be valuable but is frustrated by the geometry of the object to be radiographed. For example, extremely large objects, the separation of rocket propellants from the skin of solid fuel rocket motor, the structural integrity of an underground tank or hull of a ship, the location of buried objects, inspection of large castings etc. The author has been investigating ways to do this type of radiography and as a result has developed a technique which can be used to obtain three dimensional radiographs using Compton scattered radiation from a monochromatic source and a high efficiency, high resolution germanium spectrometer. This paper gives specific details of the reconstruction technique and presents the results of numerous numerical simulations and compares these simulations to spectra obtained in the laboratory. In addition the author presents the results of calculations made for the development of an alternative single sided radiography technique which will permit inspection of the interior of large objects. As a benchmark the author seeks to obtain three dimensional images with a resolution of about one cubic centimeter in a concrete cube 30 centimeters on a side. Such a device must use photons of very high energy. For example 30 cm of concrete represents about 15 mean free paths for photons of 100 keV, whereas at 1 MeV the attenuation is down to about five mean free paths. At these higher energies Compton scattering becomes much more probable. Although this would appear to be advantageous for single sided imaging techniques, such techniques are hampered by two side effects. In this paper the results are given of numerous Monte Carlo calculations detailing the extent of the multiple scattering and the feasibility of a variety of imaging schemes is explored.

  19. Review of Apraxia: The cognitive side of motor control

    DEFF Research Database (Denmark)

    Martínez-Ferreiro, Silvia

    2014-01-01

    Reviews the book, Apraxia: The Cognitive Side of Motor Control by G. Goldenberg (see record 2013-31133-000). The book makes a significant contribution to the study of this multifaceted syndrome, especially in relation to limb apraxia, the author’s main research area. Despite more than 100 years o...... and current state of apraxia research. (PsycINFO Database Record (c) 2014 APA, all rights reserved)...

  20. Alternatif Material Hood dan Side Panel Mobil Angkutan Pedesaan Multiguna

    Directory of Open Access Journals (Sweden)

    Muhammad Ihsan

    2015-03-01

    Full Text Available Mobil merupakan sarana transportasi yang banyak digunakan oleh manusia baik untuk kepentingan pribadi maupun umum. Pada tahun 2013 Teknik Mesin ITS bekerja sama dengan PT. Karya Tugas Anda membuat sebuah prototype mobil pick up multiguna pedesaan. Berat total prototype mobil dan box tersebut adalah 1200 Kg. Sedangkan dengan engine 650 cc dan daya 38,23 - 43,33 HP, berat mobil terlalu berat (rancangan beban total maksimum mobil dan penumpang/ barang adalah 1500 Kg. Untuk itu dilakukan kajian terhadap hood dan side panel mobil tersebut pada body bagian depan maupun box (body bagian belakang. Setelah perancangan tersebut selesai, dilanjutkan dengan merancang sambungan hood dan side panel mobil tersebut. Sambungan menggabungkan antara material pelat dengan komposit dan material komposit dengan komposit. Sambungan dianalisa kekuatannya terhadap gaya-gaya/ beban yang mungkin terjadi saat mobil digunakan. Selanjutnya dilakukan perancangan proses pembuatan hood dan side panel mobil dari bahan komposit. Hasil yang didapatkan dari penelitian ini adalah hood berdimensi 1176 mm x 453 mm dan side panel mobil dengan dimensi 558 mm x 430,5 mm. Bahan kedua komponen adalah komposit tipe E-Glass yang memiliki keuntungan lebih ringan daripada bahan sebelumnya, yaitu mild steel. Ketebalan hood yang dipilih sebesar 2 mm. Ketebalan hood tersebut aman, yaitu mampu menerima tegangan ekuivalen maksimum 7,9769 MPa dan lebih kecil daripada tegangan ijin material komposit yaitu 1020 MPa. Deformasi yang pada hood adalah sebesar 0,0247 mm. Berat dari hood mengalami perubahan, dimana dengan menggunakan bahan mild steel berat hood adalah 7,536 kg. Jika menggunakan bahan komposit berat hood menjadi 2,327 kg, hampir 69,12% lebih ringan dari sebelumnya.

  1. Possible side effects from HPV vaccination in Denmark

    DEFF Research Database (Denmark)

    Hammer, Anne; Petersen, Lone Kjeld; Rolving, Nanna;

    2016-01-01

    HPV vaccination offers protection against ~70% of cervical cancers, however, serious concerns have been raised about the possible side effects from HPV vaccination. Studies have found no increased risk of neurologic disease, autoimmune disorder, thromboembolic disease, postural orthostatic...... tachycardia syndrome, or complex regional pain syndrome in HPV-vaccinated persons compared to unvaccinated persons. Affected individuals should undergo a proper clinical examination to ensure a correct diagnosis and treatment, because symptoms might arise due to a somatic, psychiatric or functional disorder....

  2. Thin-Film Evaporative Cooling for Side-Pumped Laser

    Science.gov (United States)

    Stewart, Brian K. (Inventor)

    2010-01-01

    A system and method are provided for cooling a crystal rod of a side-pumped laser. A transparent housing receives the crystal rod therethrough so that an annular gap is defined between the housing and the radial surface of the crystal rod. A fluid coolant is injected into the annular gap such the annular gap is partially filled with the fluid coolant while the radial surface of the crystal rod is wetted as a thin film all along the axial length thereof.

  3. Distributed demand-side optimization in the smart grid

    OpenAIRE

    Atzeni, Italo

    2014-01-01

    The modern power grid is facing major challenges in the transition to a low-carbon energy sector. The growing energy demand and environmental concerns require carefully revisiting how electricity is generated, transmitted, and consumed, with an eye to the integration of renewable energy sources. The envisioned smart grid is expected to address such issues by introducing advanced information, control, and communication technologies into the energy infrastructure. In this context, demand-side m...

  4. INFLUENCE OF ELECTROACUPUNCTURE ON ARTIFICIAL ABORTION-INDUCED SIDE EFFECTS

    Institute of Scientific and Technical Information of China (English)

    田丽颖

    2001-01-01

    In the present study, the effect of electroecupuncture (EA) of acupoints of Ren, Spleen and Stomach Meridians on artificial abortion-induced side effects was observed in 100 artificial abortion women. In comparison with 45 artificial abortion women in the control group (who had not accepted EA treatment), EA possessed significant effects in relieving abdominal pain, reducing vaginal bleeding duration, lowering infection rate and infertility rate after artificial abortion operation.

  5. Enhancing Electromagnetic Side-Channel Analysis in an Operational Environment

    Science.gov (United States)

    Montminy, David P.

    Side-channel attacks exploit the unintentional emissions from cryptographic devices to determine the secret encryption key. This research identifies methods to make attacks demonstrated in an academic environment more operationally relevant. Algebraic cryptanalysis is used to reconcile redundant information extracted from side-channel attacks on the AES key schedule. A novel thresholding technique is used to select key byte guesses for a satisfiability solver resulting in a 97.5% success rate despite failing for 100% of attacks using standard methods. Two techniques are developed to compensate for differences in emissions from training and test devices dramatically improving the effectiveness of cross device template attacks. Mean and variance normalization improves same part number attack success rates from 65.1% to 100%, and increases the number of locations an attack can be performed by 226%. When normalization is combined with a novel technique to identify and filter signals in collected traces not related to the encryption operation, the number of traces required to perform a successful attack is reduced by 85.8% on average. Finally, software-defined radios are shown to be an effective low-cost method for collecting side-channel emissions in real-time, eliminating the need to modify or profile the target encryption device to gain precise timing information.

  6. Side effects of clozapine and some other psychoactive drugs.

    Science.gov (United States)

    Flanagan, Robert J

    2008-05-01

    The recognition, management, and if possible prevention, of major cardiovascular, central nervous system, haematological, and metabolic adverse effects, including diabetes mellitus and weight gain, of antipsychotics and some other drugs used to treat mental illness is a topic of much debate. However, a wide range of other adverse effects, some of which may be life-threatening, may also be encountered. Side-effects reviewed here include: gastrointestinal-associated effects (constipation, hypersalivation, oropharyngeal lesions, nasal congestion, nausea, nocturnal enuresis, and urinary retention), metabolic effects (obesity, insulin resistance, dyslipidemia, impaired glucose tolerance, and hypertension), neuromuscular effects (extrapyramidal side effects, myoclonus, and neuroleptic malignant syndrome, and pleurothotonus), thermoregulatory effects, effects on the liver, pancreas, and kidney, sexual side effects, and effects on skin and bone. Metabolic factors affecting the incidence of adverse effects to clozapine especially are also discussed. The increasing use of atypical (second generation) antipsychotics and indeed of selective serotonin reuptake inhibitors has led to a greater appreciation of not only the benefits of these drugs, but also of the spectrum of toxicity that may occur in clinical practice. The adverse effects of antipsychotics are a major factor in promoting poor adherence to, and even discontinuation of, antipsychotic treatment on the one hand, and increasing the risk of cardiovascular and metabolic disease on the other. As such they merit recognition and either harm minimization strategies (use of the minimum effective dose, or use of lower doses of combinations of antipsychotics), or in extreme cases discontinuation of the offending drug(s).

  7. Review about gabapentin misuse, interactions, contraindications and side effects.

    Science.gov (United States)

    Quintero, Gabriel C

    2017-01-01

    The current work is targeted to review the risks of gabapentin misuse, its potential interactions with other drugs, side effects and use contraindications. This review consists of a total of 99 biographical references (from the year 1983 to 2016). A publication search of PubMed was performed from January 1983 to December 2016. It included animal studies, clinical studies, case studies and reviews related to gabapentin misuse, potential interactions, side effects and use contraindications. The search terms were gabapentin, anticonvulsant and antiepileptic. In general, it seems that gabapentin has risks of being misused based on the increased level of prescriptions, related fatalities, recreational misuse and higher doses of self-administration. The main reasons for gabapentin misuse are as follows: getting high, alleviating opioid withdrawal symptoms and potentiating methadone effects. Some of the main substances that interact with gabapentin are morphine, caffeine, losartan, ethacrynic acid, phenytoin, mefloquine and magnesium oxide. Some of the side effects caused by gabapentin are teratogenicity, hypoventilation, respiratory failure and myopathy. Finally, reports in general contraindicate the use of gabapentin in conditions such as myasthenia gravis and myoclonus.

  8. NEW DYNAMICS OF THE CONFLICT BETWEEN TWO SIDES IN SCHOOLS

    Directory of Open Access Journals (Sweden)

    Pablo Ortega Gil

    2016-12-01

    Full Text Available This paper contains my own thoughts concerning what I have called new dynamics of the conflict between two sides in Schools. It begins by presenting the contrast between traditional conflicts, where both sides believed their argument was a private affair, and these new dynamics where one or both sides of the conflict tend to make it public and work to win support for their cause. The furious confrontation some people seek and the waves of indignation they set off bring to mind the frequent social media shitstorms we hear about. As a consequence, as the conflict festers, the inspector of education receives countless visits, phone calls and protest letters, an uproar designed to influence her decision. Next, some real cases are discussed, although no information is given of the people taking parts in the events to safeguard identities. Finally, I propose a checklist that involves a sequence of steps designed to protect the inspector from pressure and help her deal more efficiently with problems of this nature.

  9. Kinematic analysis of the double side kick in pointfighting, kickboxing.

    Science.gov (United States)

    Hölbling, Dominik; Preuschl, Emanuel; Hassmann, Michaela; Baca, Arnold

    2017-02-01

    The double side kick is a frequently used technique in pointfighting on which most offensive kicking techniques are based on. The aim of the study was to identify parameters, e.g., trunk and leg positions, durations and velocities that affect successful technique execution. 44 fighters, male and female, including European and World champions, participated in the research. The participants performed double side kicks to a punching bag with the target at chest level. 10 international experts scored (1-10 points; interrater correlation ICC (3,1): 0.952) videos of the best individual trial for quality of technique execution. Based on the average of the scores participants were categorised into 2 equally sized groups. For kinematic data acquisition, a Vicon 3D-motion capturing system was used. The normalised knee height of the kick leg (KHK), normalised absolute distance to the frontal shoulder (DKS) at the end of both chambering phases, the horizontal velocity during both chambering phases (KEV), the durations of all 6 functional phases and total duration, were analysed. KHK1, KHK2, DKS1 and DKS2, total duration as well as 4 out of 6 phase durations and KEV1 showed significant differences between groups in two-sided t-test or Mann-Whitney U-test for not normally distributed variables.

  10. Residual Distributed Compressive Video Sensing Based on Double Side Information

    Institute of Scientific and Technical Information of China (English)

    CHEN Jian; SU Kai-Xiong; WANG Wei-Xing; LAN Cheng-Dong

    2014-01-01

    Compressed sensing (CS) is a novel technology to acquire and reconstruct sparse signals below the Nyquist rate. It has great potential in image and video acquisition and processing. To effectively improve the sparsity of signal being measured and reconstructing efficiency, an encoding and decoding model of residual distributed compressive video sensing based on double side information (RDCVS-DSI) is proposed in this paper. Exploiting the characteristics of image itself in the frequency domain and the correlation between successive frames, the model regards the video frame in low quality as the first side information in the process of coding, and generates the second side information for the non-key frames using motion estimation and compensation technology at its decoding end. Performance analysis and simulation experiments show that the RDCVS-DSI model can rebuild the video sequence with high fidelity in the consumption of quite low complexity. About 1∼5 dB gain in the average peak signal-to-noise ratio of the reconstructed frames is observed, and the speed is close to the least complex DCVS, when compared with prior works on compressive video sensing.

  11. Heat transfer modeling of double-side arc welding

    CERN Document Server

    Sun Jun Sheng; Zhang Yan Ming

    2002-01-01

    If a plasma arc and a TIG arc are connected in serial and with the plasma arc placed on the obverse side and the TIG arc on the opposite side of the workpiece, a special double-side arc welding (DSAW) system will be formed, in which the PAW current is forced to flow through the keyhole along the thickness direction so as to compensate the energy consumed for melting the workpiece and improve the penetration capacity of the PAW arc. By considering the mechanics factors which influence the DSAW pool geometric shape, the control equations of the pool surface deformation are derived, and the mathematics mode for DSAW heat transfer is established by using boundary-fitted non-orthogonal coordinate systems. With this model, the difference between DSAW and PAW heat transfer is analyzed and the reason for the increase of DSAW penetration is explained from the point of heat transfer. The welding process experiments show that calculated results are in good agreement with measured ones

  12. Review about gabapentin misuse, interactions, contraindications and side effects

    Science.gov (United States)

    Quintero, Gabriel C

    2017-01-01

    The current work is targeted to review the risks of gabapentin misuse, its potential interactions with other drugs, side effects and use contraindications. This review consists of a total of 99 biographical references (from the year 1983 to 2016). A publication search of PubMed was performed from January 1983 to December 2016. It included animal studies, clinical studies, case studies and reviews related to gabapentin misuse, potential interactions, side effects and use contraindications. The search terms were gabapentin, anticonvulsant and antiepileptic. In general, it seems that gabapentin has risks of being misused based on the increased level of prescriptions, related fatalities, recreational misuse and higher doses of self-administration. The main reasons for gabapentin misuse are as follows: getting high, alleviating opioid withdrawal symptoms and potentiating methadone effects. Some of the main substances that interact with gabapentin are morphine, caffeine, losartan, ethacrynic acid, phenytoin, mefloquine and magnesium oxide. Some of the side effects caused by gabapentin are teratogenicity, hypoventilation, respiratory failure and myopathy. Finally, reports in general contraindicate the use of gabapentin in conditions such as myasthenia gravis and myoclonus. PMID:28223849

  13. Results from the DarkSide-50 Dark Matter Experiment

    Energy Technology Data Exchange (ETDEWEB)

    Fan, Alden [Univ. of California, Los Angeles, CA (United States)

    2016-01-01

    While there is tremendous astrophysical and cosmological evidence for dark matter, its precise nature is one of the most significant open questions in modern physics. Weakly interacting massive particles (WIMPs) are a particularly compelling class of dark matter candidates with masses of the order 100 GeV and couplings to ordinary matter at the weak scale. Direct detection experiments are aiming to observe the low energy (<100 keV) scattering of dark matter off normal matter. With the liquid noble technology leading the way in WIMP sensitivity, no conclusive signals have been observed yet. The DarkSide experiment is looking for WIMP dark matter using a liquid argon target in a dual-phase time projection chamber located deep underground at Gran Sasso National Laboratory (LNGS) in Italy. Currently filled with argon obtained from underground sources, which is greatly reduced in radioactive 39Ar, DarkSide-50 recently made the most sensitive measurement of the 39Ar activity in underground argon and used it to set the strongest WIMP dark matter limit using liquid argon to date. This work describes the full chain of analysis used to produce the recent dark matter limit, from reconstruction of raw data to evaluation of the final exclusion curve. The DarkSide- 50 apparatus is described in detail, followed by discussion of the low level reconstruction algorithms. The algorithms are then used to arrive at three broad analysis results: The electroluminescence signals in DarkSide-50 are used to perform a precision measurement of ii longitudinal electron diffusion in liquid argon. A search is performed on the underground argon data to identify the delayed coincidence signature of 85Kr decays to the 85mRb state, a crucial ingredient in the measurement of the 39Ar activity in the underground argon. Finally, a full description of the WIMP search is given, including development of cuts, efficiencies, energy scale, and exclusion

  14. Side chain conformational averaging in human dihydrofolate reductase.

    Science.gov (United States)

    Tuttle, Lisa M; Dyson, H Jane; Wright, Peter E

    2014-02-25

    The three-dimensional structures of the dihydrofolate reductase enzymes from Escherichia coli (ecDHFR or ecE) and Homo sapiens (hDHFR or hE) are very similar, despite a rather low level of sequence identity. Whereas the active site loops of ecDHFR undergo major conformational rearrangements during progression through the reaction cycle, hDHFR remains fixed in a closed loop conformation in all of its catalytic intermediates. To elucidate the structural and dynamic differences between the human and E. coli enzymes, we conducted a comprehensive analysis of side chain flexibility and dynamics in complexes of hDHFR that represent intermediates in the major catalytic cycle. Nuclear magnetic resonance relaxation dispersion experiments show that, in marked contrast to the functionally important motions that feature prominently in the catalytic intermediates of ecDHFR, millisecond time scale fluctuations cannot be detected for hDHFR side chains. Ligand flux in hDHFR is thought to be mediated by conformational changes between a hinge-open state when the substrate/product-binding pocket is vacant and a hinge-closed state when this pocket is occupied. Comparison of X-ray structures of hinge-open and hinge-closed states shows that helix αF changes position by sliding between the two states. Analysis of χ1 rotamer populations derived from measurements of (3)JCγCO and (3)JCγN couplings indicates that many of the side chains that contact helix αF exhibit rotamer averaging that may facilitate the conformational change. The χ1 rotamer adopted by the Phe31 side chain depends upon whether the active site contains the substrate or product. In the holoenzyme (the binary complex of hDHFR with reduced nicotinamide adenine dinucleotide phosphate), a combination of hinge opening and a change in the Phe31 χ1 rotamer opens the active site to facilitate entry of the substrate. Overall, the data suggest that, unlike ecDHFR, hDHFR requires minimal backbone conformational rearrangement as

  15. Time-Domain Simulation for Coupled Motions of Three Barges Moored Side-by-Side in Floatover Operation

    Institute of Scientific and Technical Information of China (English)

    许鑫; 杨建民; 李欣; 徐亮瑜

    2015-01-01

    Simulating the coupled motions of multiple bodies in the time domain is a complex problem because of the strong hydrodynamic interactions and coupled effect of various mechanical connectors. In this study, we investigate the hydrodynamic responses of three barges moored side-by-side in a floatover operation in the frequency and time domains. In the frequency domain, the damping lid method is adopted to improve the overestimated hydrodynamic coefficients calculated from conventional potential flow theory. A time-domain computing program based on potential flow theory and impulse theory is compiled for analyses that consider multibody hydrodynamic interactions and mechanical effects from lines and fenders. Correspondingly, an experiment is carried out for comparison with the numerical results. All statistics, time series, and power density spectra from decay and irregular wave tests are in a fairly good agreement.

  16. WAKE PATTERNS OF FLOW PAST A PAIR OF CIRCULAR CYLINDERS IN SIDE-BY-SIDE ARRANGEMENTS AT LOW REYNOLDS NUMBERS

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    A flow past two side-by-side identical circular cylinders was numerically investigated with the unstructured spectral element method. From the computational results at various non-dimensional distances between cylinder centers T/D and the Reynolds number Re, a total of nine kinds of wake patterns were observed: four steady wake patterns, including single bluff-body steady pattern, separated double-body steady pattern and transition steady pattern for sub-critical Reynolds numbers and biased steady pattern for super-critical Reynolds numbers, and five unsteady wake patterns, including single bluff-body periodic pattern, biased quasi-steady pattern, quasi-periodic (flip-flopping) pattern, in-phase-synchronized pattern and anti-phase-synchronized pattern. Time evolution of lift and drag coefficients corresponding to each unsteady wake pattern was given.

  17. Numerical simulation of fluid flow of two rotating side-by-side circular cylinders by Lattice Boltzmann method

    Science.gov (United States)

    Nemati, Hasan; Sedighi, Kurosh; Farhadi, Mousa; Pirouz, Mohammad Mohammadi; Fattahi, Ehsan

    2010-03-01

    A numerical investigation of the two-dimensional laminar flow around side-by-side rotating circular cylinders using Lattice Boltzmann method is conducted. The effects of variation of rotational speed ratio β and different gap spacings g* at Reynolds number of 100 are studied. A various range of rotational speed ratio 0 ≤ β ≤ 2 for four different gap spacings of 3, 1.5, 0.7 and 0.2 are investigated. Flow conditions and its characteristics, such as lift and drag coefficients and Strouhal number, is studied. The results indicated that as β increases, the flow changes its condition from periodic to steady after a critical rotational speed. Results also indicated that variation of the gap spacing and rotational speed has significant effect on wake pattern. Wake pattern in turn has significant effect on the Strouhal number. Finally, the result is compared with experimental and other numerical data.

  18. Thickness control and interface quality as functions of slurry formulation and casting speed in side-by-side tape casting

    DEFF Research Database (Denmark)

    Bulatova, Regina; Jabbari, Mirmasoud; Kaiser, Andreas;

    2014-01-01

    A novel method of co-casting called side-by-side tape casting was developed aiming to form thin functionally graded films with varying properties within a single plane. The standard organic-based recipe was optimized to co-cast slurries into thick graded tapes. Performed numerical simulations...... identified the stable flow beneath the blade with a shear rate profile independent of slurry viscosity as long as the slurry load in the casting tank was low. Thickness and interface shape could be well predicted if the rheological behaviour of slurries is known and the processing parameters are well......-controlled. A well-defined steep interface was obtained by co-casting slurries with similar viscosities above 4000mPas at a speed of 40cm/min. The elastic properties of green tapes were proven to be defined by the binder concentration in the recipe formulation. The interfaces in graded tapes were shown to withstand...

  19. Side effects of aesthetic therapy by lasers and IPL source: a dark side of the correct management of the patients

    Science.gov (United States)

    Oskarbski, George V.

    2004-09-01

    A medical practice by laser or IPL device means professional experience, reputation, strong economical investment, while a patient needs results for the bill he pays. In front of a publicity of non-invasive solutions for a broad base of clinical applications, the everyday practice offers embarrassing side effects about which it is better to prepare the users. Inefficiency, hypo-hyper-pigmentations, scars show that we need to have clear instructions and experienced studies, before emphasizing good results.

  20. Computer cooling using a two phase minichannel thermosyphon loop heated from horizontal and vertical sides and cooled from vertical side

    Science.gov (United States)

    Bieliński, Henryk; Mikielewicz, Jarosław

    2010-10-01

    In the present paper it is proposed to consider the computer cooling capacity using the thermosyphon loop. A closed thermosyphon loop consists of combined two heaters and a cooler connected to each other by tubes. The first heater may be a CPU processor located on the motherboard of the personal computer. The second heater may be a chip of a graphic card placed perpendicular to the motherboard of personal computer. The cooler can be placed above the heaters on the computer chassis. The thermosyphon cooling system on the use of computer can be modeled using the rectangular thermosyphon loop with minichannels heated at the bottom horizontal side and the bottom vertical side and cooled at the upper vertical side. The riser and a downcomer connect these parts. A one-dimensional model of two-phase flow and heat transfer in a closed thermosyphon loop is based on mass, momentum, and energy balances in the evaporators, rising tube, condenser and the falling tube. The separate two-phase flow model is used in calculations. A numerical investigation for the analysis of the mass flux rate and heat transfer coefficient in the steady state has been accomplished.

  1. Difference between right and left side in total knee and unicondylar knee replacement: An interesting observation

    Directory of Open Access Journals (Sweden)

    Vasudevan Thirumal Selvan

    2005-02-01

    Full Text Available We report an observation made about the differences between right and left side in case of total knee and unicondylar knee replacement. It was found that unicondylar knee replacement was performed more commonly on the left side (66%, as compared to only 34% on right side, where as total knee replacement was more common on the right side (64% as compared to 36% on left side. The exact clinical utility of this difference is yet to be known.

  2. Demographic side effects of selective hunting in ungulates and carnivores.

    Science.gov (United States)

    Milner, Jos M; Nilsen, Erlend B; Andreassen, Harry P

    2007-02-01

    Selective harvesting regimes are often implemented because age and sex classes contribute differently to population dynamics and hunters show preferences associated with body size and trophy value. We reviewed the literature on how such cropping regimes affect the demography of the remaining population (here termed demographic side effects). First, we examined the implications of removing a large proportion of a specific age or sex class. Such harvesting strategies often bias the population sex ratio toward females and reduce the mean age of males, which may consequently delay birth dates, reduce birth synchrony, delay body mass development, and alter offspring sex ratios. Second, we reviewed the side effects associated with the selective removal of relatively few specific individuals, often large trophy males. Such selective harvesting can destabilize social structures and the dominance hierarchy and may cause loss of social knowledge, sexually selected infanticide, habitat changes among reproductive females, and changes in offspring sex ratio. A common feature of many of the reported mechanisms is that they ultimately depress recruitment and in some extreme cases even cause total reproductive collapse. These effects could act additively and destabilize the dynamics of populations, thus having a stronger effect on population growth rate than first anticipated. Although more experimental than observational studies reported demographic side effects, we argue that this may reflect the quite subtle mechanisms involved, which are unlikely to be detected in observational studies without rigorous monitoring regimes. We call for more detailed studies of hunted populations with marked individuals that address how the expression of these effects varies across mating systems, habitats, and with population density. Theoretical models investigating how strongly these effects influence population growth rates are also required.

  3. TRAPPIST monitoring of comet C/2013 A1 (Siding Spring)

    Science.gov (United States)

    Opitom, Cyrielle; Jehin, Emmanuël; Manfroid, Jean; Hutsemékers, Damien; Gillon, Michaël

    2014-11-01

    C/2013 A1 (Siding Spring) is a long period comet discovered by Robert H McNaught at Siding Spring Observatory in Australia on January 3, 2013 at 7.2 au from the Sun. This comet will make a close encounter with Mars on October 19, 2014. At this occasion the comet will be extensively observed both from Earth and from several orbiters around Mars.On September 20, 2013 when the comet was around 5 au from the Sun, we started a monitoring with the TRAPPIST robotic telescope installed at La Silla observatory [1]. A set of narrowband cometary filters designed by the NASA for the Hale-Bopp Observing Campaign [2] is permanently mounted on the telescope along with classic Johnson-Cousins B, V, Rc, and Ic filters.We observed the comet continuously at least once a week from September 20, 2013 to April 6, 2014 with broad band filters. We then recovered the comet on May 20. At this time we could detect the gas and started the observations with narrow band filters until early November, covering the close approach to Mars and the perihelion passage.We present here our first results about comet Siding Springs. From the images in the broad band filters and in the dust continuum filters we derived A(θ)fρ values [3] and studied the evolution of the comet activity with the heliocentric distance from September 20, 2013 to early November 2014. We could also detect gas since May 20, 2014. We thus derived gas production rates using a Haser model [4]. We present the evolution of gas production rates and gas production rates ratios with the heliocentric distance.Finally, we discuss the dust and gas coma morphology.

  4. The Afghan Mission: The Other Side of the COIN

    Directory of Open Access Journals (Sweden)

    Luděk MORAVEC

    2010-12-01

    Full Text Available This article called “The Afghan Mission: The Other Side of the COIN” brings an evaluation of NATO and the Taliban strategies in contemporary Afghanistan. The strategic choice of both actors is researched using the concept of the “centers of gravity” and confronted with a specific situation on the ground. Furthermore, additional attention is paid to the struggle for hearts and minds and its role in NATO’s strategy. The paper is concluded with the determination of a single center of gravity of the NATO-Taliban confrontation which is offered as the evaluation criterion for further steps to be used in the Afghan war.

  5. Imageology and clinical examination: Two sides of the same coin

    Directory of Open Access Journals (Sweden)

    Deepa Das

    2011-01-01

    Full Text Available The continuous and rapid transition of techniques from research lab into clinical practice has been the pattern of development in radiology and imaging, and this has put the concept of clinical imaging into a different perspective. From a passive role of pattern recognition, distinguishing a radiograph from normal to abnormal, the task of a radiologist today has been elevated to reporting a comprehensive clinical imaging assay, giving information at a level profound enough to be useful for scientists working in allied fields. A peep into the literature shows how radiological and clinical examination can be two sides of the same coin.

  6. STUDY ON SIDE REACTION IN THE SYNTHESIS OF HYPERCROSSLINKED POLYMERS

    Institute of Scientific and Technical Information of China (English)

    ZHANG Bo; LI Aimin; TAO Weihua; YANG Weiben

    2008-01-01

    The systematical study about side reactions have revealed the formation mechanism of oxygen-containing groups of hypercrosslinked polymers.Surface chemistry and functionality of the polymers are characterized by Fourier-transform infrared spectroscopy (FT-IR), solid state nuclear magnetic resonance (NMR) and contact angle.The results showed that the ether groups were from chioromethylated reaction, and the alcohol groups arose from partial hydrolysis of chloromethyl groups during the post-crosslinking reaction, and the carbonyl functionality was formed by further oxidation of the alcohol groups.Catalyst and solvent used in the postcrosslinking reaction would greatly influence the surface chemistry of the polymer.

  7. Pandemic influenza vaccines and neuraminidase inhibitors: efficacy and side effects.

    Science.gov (United States)

    Bijl, D

    2011-01-01

    At the time of the outbreak of the pandemic of New Influenza A (H1N1) pandemic influenza vaccines became available via an accelerated registration procedure. In 2005 large stocks of the neuraminidase inhibitor oseltamivir were built up in the Netherlands and other western countries. There was considerable doubt about the efficacy of this medicine. Initially reported positive effects of the drug were largely based on unpublished research, which was sponsored by the manufacturer and was partially written by ghostwriters. There now have been reports of rare and serious side effects. The first reports on the severity of the pandemic in Australia and New Zealand indicated a mild course.

  8. Extrapyramidal side effects with low doses of amisulpride.

    Science.gov (United States)

    Mandal, Nikhiles; Singh, Om P; Sen, Subrata

    2014-04-01

    Amisulpride, the newly introduced antipsychotic in India, is claimed to be effective in both positive and negative symptom schizophrenia and related disorders, though it has little or no action on serotonergic receptors. Limbic selectivity and lower striatal dopaminergic receptor binding capacity causes very low incidence of EPS. But, in clinical practice, we are getting EPS with this drug even at lower doses. We have reported three cases of akathisia, acute dystonia, and drug-induced Parkinsonism with low doses of amisulpride. So, we should keep this side effect in mind when using amisulpride. In fact, more studies are required in our country to find out the incidence of EPS and other associated mechanism.

  9. Three Sides Billboard Wind-Solar Hybrid System Design

    Directory of Open Access Journals (Sweden)

    Bai Xuefeng

    2015-01-01

    Full Text Available With the high development of world economy, the demand of energy is increasing all the time, As energy shortage and environment problem are increasing outstanding, Renewable energy has been attracting more and more attention. A kind of three sides billboard supply by wind-Solar hybrid system has been designed in this paper, the overall structure of the system, components, working principle and control strategy has been analyzed from the system perspective. The software and hardware of the system are debugged together and the result is acquired. System function is better and has achieved the expected results.

  10. Uranium density reduction on fuel element side plates assessment

    Energy Technology Data Exchange (ETDEWEB)

    Rios, Ilka A. [Centro Tecnologico da Marinha em Sao Paulo (CTMSP), Sao Paulo, SP (Brazil); Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil); Andrade, Delvonei A.; Domingos, Douglas B.; Umbehaun, Pedro E. [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2011-07-01

    During operation of IEA-R1 research reactor, located at Instituto de Pesquisas Energeticas e Nucleares, IPEN - CNEN/SP, an abnormal oxidation on some fuel elements was noted. It was also verified, among the possible causes of the problem, that the most likely one was insufficient cooling of the elements in the core. One of the propositions to solve or minimize the problem is to reduce uranium density on fuel elements side plates. In this paper, the influence of this change on neutronic and thermal hydraulic parameters for IEA-R1 reactor is verified by simulations with the codes HAMMER and CITATION. Results are presented and discussed. (author)

  11. Side Information in Spread-Spectrum Packet Radio Networks

    Science.gov (United States)

    1991-06-21

    coaft~ biof nf ormaion. $an C40tf~i rgading th. bwdieft eistat ofy Aŕ auti o fIII"IIII w to IInoq -Saaunf Sw-f OW90rtfo o I ns ovn atii j ntml..dii W...probabilities listed in Table 2 are not changed . Recall that these are the probabilities that a symbol is in error given the type of interference present...interval. So,pj,p are not changed and ais taken to be a’andflis taken to be 3’. To be able to compare the side information schemes, certain precautions must

  12. Transmit antenna selection based on shadowing side information

    KAUST Repository

    Yilmaz, Ferkan

    2011-05-01

    In this paper, we propose a new transmit antenna selection scheme based on shadowing side information. In the proposed scheme, single transmit antenna which has the highest shadowing coefficient is selected. By the proposed technique, usage of the feedback channel and channel estimation complexity at the receiver can be reduced. We consider independent but not identically distributed Generalized-K composite fading model, which is a general composite fading & shadowing channel model for wireless environments. Exact closed-form outage probability, moment generating function and symbol error probability expressions are derived. In addition, theoretical performance results are validated by Monte Carlo simulations. © 2011 IEEE.

  13. Deploying Server-side File System Monitoring at NERSC

    Energy Technology Data Exchange (ETDEWEB)

    Uselton, Andrew

    2009-05-01

    The Franklin Cray XT4 at the NERSC center was equipped with the server-side I/O monitoring infrastructure Cerebro/LMT, which is described here in detail. Insights gained from the data produced include a better understanding of instantaneous data rates during file system testing, file system behavior during regular production time, and long-term average behaviors. Information and insights gleaned from this monitoring support efforts to proactively manage the I/O infrastructure on Franklin. A simple model for I/O transactions is introduced and compared with the 250 million observations sent to the LMT database from August 2008 to February 2009.

  14. Balanced Weights and Three-Sided Coalition Formation

    Directory of Open Access Journals (Sweden)

    Emiliya Lazarova

    2010-06-01

    Full Text Available We consider three-sided coalition formation problems when each agent is concerned about his local status as measured by his relative rank position within the group of his own type and about his global status as measured by the weighted sum of the average rankings of the other types of groups. We show that a core stable coalition structure always exists, provided that the corresponding weights are balanced and each agent perceives the two types of status as being substitutable.

  15. An alternate side coupled structure for the Fermilab LINAC upgrade

    Energy Technology Data Exchange (ETDEWEB)

    Jurgens, T.G.; Kerns, Q.A.; Fritz, J.R.; May, M.A.

    1988-10-01

    An alternate side coupled structure (SCS) is being investigated. Comparisons are made to the traditional SCS. Mechanical comparisons include the relative cost and ease of fabrication. This discussion also addresses the use of CNC machining. Electrical comparisons include field distributions and coupling constants. Measured and numerical data are presented. The coupling constant of the alternate SCS is adjusted by independently changing either the separation of the coupling and accelerating cavity centers or the length of the slot. These two parameters are not independent in the traditional SCS design. 4 refs., 5 figs

  16. Impact of Demand Side Management in Active Distribution Networks

    DEFF Research Database (Denmark)

    Ponnaganti, Pavani; Bak-Jensen, Birgitte; Pillai, Jayakrishnan Radhakrishna

    2017-01-01

    Demand Side Management (DSM) is an efficient flexible program which helps distribution network operators to meet the future critical peak demand. It is executed in cases of not only technical issues like voltage sag or swell, transformer burdening, cable congestions, but also to increase the degree...... of visibility in the electricity markets. The aim of this paper is to find the optimal flexible demands that can be shifted to another time in order to operate the active distribution system within secure operating limits. A simple mechanism is proposed for finding the flexibility of the loads where electric...

  17. Demand side integration aspects in active distribution planning

    DEFF Research Database (Denmark)

    Silvestro, Federico; Baitch, Alex; Pilo, Fabrizio

    2013-01-01

    will be implemented in practice? How will regulatory frameworks and connection agreements evolve to support ADSs? The present work provides some information about the closer and closer integration between network planning and Demand Side Integration that is foreseen in the future and shows the necessity to develop......This paper presents an overview of the activities of CIGRE Working Group WG C6.19 (WG), focusing on the planning and optimization of active distribution systems. A key challenge in planning Active Distribution Systems (ADSs) is the uncertainty of the future, i.e., what level of active management...

  18. Demand Side Management in Pellet Production: Internal and External Factors

    Directory of Open Access Journals (Sweden)

    Vigants Haralds

    2014-12-01

    Full Text Available This paper demonstrates a demand side management case study: how to save energy and how research and data analysis help to create an energy management system in a pellet production facility; and shows ways to implement the EU energy efficiency directive in production facilities. The study carried out in this research serves as a far-reaching step that can be taken to improve energy efficiency during the operation mode of technological equipment. The benchmarking methodology is used for analysis of results.

  19. Indirect Control for Demand Side Management – A Conceptual Introduction

    DEFF Research Database (Denmark)

    Heussen, Kai; You, Shi; Biegel, Benjamin

    2012-01-01

    correct definition, either as a control or a market concept. This paper aims to provide a conceptual introduction to "indirect control" for management of small and distributed demand side resources. A review of control concepts and an analysis of "indirectness" features are provided to create a framework......The concept of “indirect control” has become a relevant discussion term in relation to activation distributed and small-scale demand and generation units to provide resources for power system balancing. The term and its association with price signals has, however caused some confusion as to its...

  20. The quantitative side of the Repertory Grid Technique: some concerns

    CERN Document Server

    Karapanos, Evangelos

    2009-01-01

    User experience (UX) evaluation is gaining increased interest lately, both from academia and industry. In this paper we argue that UX evaluation needs to fulfill two important requirements: scalability, i.e. the ability to provide useful feedback in different stages of the design, and diversity, i.e. the ability to reflect the di-versity of opinions that may exist in different users. We promote the use of the Repertory Grid Technique as a promising UX evaluation technique and discuss some of our concerns regarding the quantitative side of its use.

  1. Hermetic electronics package with dual-sided electrical feedthrough configuration

    Science.gov (United States)

    Shah, Kedar G.; Pannu, Satinderpall S.

    2016-11-22

    A hermetic electronics package includes a metal case with opposing first and second open ends, with each end connected to a first feedthrough construction and a second feedthrough construction. Each feedthrough contruction has an electrically insulating substrate and an array of electrically conductive feedthroughs extending therethrough, with the electrically insulating substrates connected to the opposing first and second open ends, respectively, of the metal case so as to form a hermetically sealed enclosure. A set of electronic components are located within the hermetically sealed enclosure and are operably connected to the feedthroughs of the first and second feedthrough constructions so as to electrically communicate outside the package from opposite sides of the package.

  2. Photorealistic ray tracing to visualize automobile side mirror reflective scenes.

    Science.gov (United States)

    Lee, Hocheol; Kim, Kyuman; Lee, Gang; Lee, Sungkoo; Kim, Jingu

    2014-10-20

    We describe an interactive visualization procedure for determining the optimal surface of a special automobile side mirror, thereby removing the blind spot, without the need for feedback from the error-prone manufacturing process. If the horizontally progressive curvature distributions are set to the semi-mathematical expression for a free-form surface, the surface point set can then be derived through numerical integration. This is then converted to a NURBS surface while retaining the surface curvature. Then, reflective scenes from the driving environment can be virtually realized using photorealistic ray tracing, in order to evaluate how these reflected images would appear to drivers.

  3. STUDY ON SIDE REACTION IN THE SYNTHESIS OF HYPERCROSSLINKED POLYMERS

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    The systematical study about side reactions have revealed the formation mechanism of oxygen-containing groups of hypercrosslinked polymers. Surface chemistry and functionality of the polymers are characterized by Fourier-transform infrared spectroscopy (FT-IR), solid state nuclear magnetic resonance (NMR) and contact angle. The results showed that the ether groups were from chloromethylated reaction, and the alcohol groups arose from partial hydrolysis of chloromethyl groups during the post-crosslinking reaction, and the carbonyl functionality was formed by further oxidation of the alcohol groups. Catalyst and solvent used in the postcrosslinking reaction would greatly influence the surface chemistry of the polymer.

  4. Numerical simulation of hot stamping of side impact beam

    Institute of Scientific and Technical Information of China (English)

    Guo Yihui; Ma Mingtu; Fang Gang; Song Leifeng; Liu Qiang; Wang Xiaona; Zhou Dianwu

    2012-01-01

    Ls-DYNA software is adopted to conduct research of numerical simulation on hot stamping of side impact beam to calculate the temperature field distribution, stress field distribution, forming limit diagram (FLD) figure, etc. in the course of hot stamping so as to predict and analyze the formability of parts. ProCAST software is employed to conduct research of numerical simulation on solid quenching course concerning hot stamping to calculate temperature field distri- bution of tools and component of muhiple stamping cycles. The results obtained from numerical simulation can provide significant reference value to hot stamping part design, formability predication and tools cooling system design.

  5. The Dark Side of Software Engineering Evil on Computing Projects

    CERN Document Server

    Rost, Johann

    2010-01-01

    Betrayal! Corruption! Software engineering? Industry experts Johann Rost and Robert L. Glass explore the seamy underbelly of software engineering in this timely report on and analysis of the prevalance of subversion, lying, hacking, and espionage on every level of software project management. Based on the authors' original research and augmented by frank discussion and insights from other well-respected figures, The Dark Side of Software Engineering goes where other management studies fear to tread -- a corporate environment where schedules are fabricated, trust is betrayed, millions of dollar

  6. Primary Control by ON/OFF Demand-Side Devices

    DEFF Research Database (Denmark)

    Biegel, Benjamin; Hansen, Lars Henrik; Andersen, Palle

    2013-01-01

    manage the portfolio of devices to collectively provide a primary reserve delivery in an unbundled liberalized electricity market setting under current regulations. Furthermore, we formulate a binary linear optimization problem that minimizes the aggregator’s cost of providing a primary reserve delivery......We consider an aggregator managing a portfolio of ON/OFF demand-side devices. The devices are able to shift con- sumption in time within certain energy limitations; moreover, the devices are able to measure the system frequency and switch ON and OFF accordingly. We show how the aggregator can...

  7. Automated Client-side Sanitizer for Code Injection Attacks

    Directory of Open Access Journals (Sweden)

    Dnyaneshwar K. Patil

    2016-04-01

    Full Text Available Web applications are useful for various online services. These web applications are becoming ubiquitous in our daily lives. They are used for multiple purposes such as e-commerce, financial services, emails, healthcare services and many other captious services. But the presence of vulnerabilities in the web application may become a serious cause for the security of the web application. A web application may contain different types of vulnerabilities. Cross-site scripting is one of the type of code injection attacks. According to OWASP TOP 10 vulnerability report, Cross-site Scripting (XSS is among top 5 vulnerabilities. So this research work aims to implement an effective solution for the prevention of cross- site scripting vulnerabilities. In this paper, we implemented a novel client-side XSS sanitizer that prevents web applications from XSS attacks. Our sanitizer is able to detect cross-site scripting vulnerabilities at the client-side. It strengthens web browser, because modern web browser do not provide any specific notification, alert or indication of security holes or vulnerabilities and their presence in the web application.

  8. The Other Side of Gravity and Geometry: Antigravity and Anticurvature

    Directory of Open Access Journals (Sweden)

    M. I. Wanas

    2012-01-01

    Full Text Available Gravity is one of the four known fundamental interactions used to study and interpret physical phenomenae. It governs diverse phenomenae, especially those connected with large-scale structures. From more than one decade, existing gravity theories have suffered from some problems, when confronting their predictions with the results of some experiments and observations. This situation has led to many suggestions, none of which is final, so far. Here, we show that the assumption of existence of another side of gravity, a repulsive gravity or antigravity, together with its attractive side, may give a satisfactory solution to gravity problems. We caught here two pieces of evidence for the existence of antigravity in nature. The first is on the laboratory scale, the COW experiment, and the second is on the cosmic scale, SN type Ia observation. On the other hand, we show how gravity theories can predict antigravity, using a new defined geometric object called Parameterized anticurvature. This shows clearly how Einstein's geometrization philosophy can solve recent gravity problems in a satisfactory and easy way. Also, it may throw some light on the mystery of physical nature of “Dark Energy.”

  9. Double side electroplating for applying beta voltaic with sandwich structure

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Sang Moo; Uhm, Young Rang; Son, Kwang Jae; Kim, Jong Bum; Kim, Jin Joo; Park, Jong Han [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2015-05-15

    As a result, a variety of nuclear-based small-scale power sources have been developed with varying degrees of success and maturity. A nuclear battery with diode junction is a device that converts nuclear radiation directly to electric power. The mechanism of a nuclear battery is same as the P-N junction diode for solar cell application. The photovoltaic is operated by converted photons to electrical energy in the junction. In betavoltaic battery, beta particles are collected and converted to electrical energy as similar principle as photovoltaic. A very low current, order of nano or micro amperes, is generated in devices. The difference of the short circuit current between the pre-deposition and post deposition of Ni-63 was found to be 5 nA. This value is very low to apply device junction. To fabricate betavoltaic, Ni-63 should be coated on the double side of substrate. The bath was primarily composed of 0.2 M Ni ions, prepared by dissolving Ni metal particles in HCl. The prototype for electroplating radioactive Ni-63 on double side has been established.

  10. Measurement of Bd mixing using opposite-side flavor tagging

    CERN Document Server

    Abazov, V M; Abolins, M; Acharya, B S; Adams, M; Adams, T; Agelou, M; Aguiló, E; Ahn, S H; Ahsan, M; Alexeev, G D; Alkhazov, G; Alton, A; Alverson, G; Alves, G A; Anastasoaie, M; Andeen, T; Anderson, S; Andrieu, B; Anzelc, M S; Arnoud, Y; Arov, M; Askew, A; Åsman, B; Assis-Jesus, A C S; Atramentov, O; Autermann, C; Avila, C; Ay, C; Badaud, F; Baden, A; Bagby, L; Baldin, B; Bandurin, D V; Banerjee, P; Banerjee, S; Barberis, E; Bargassa, P; Baringer, P; Barnes, C; Barreto, J; Bartlett, J F; Bassler, U; Bauer, D; Beale, S; Bean, A; Begalli, M; Begel, M; Belanger-Champagne, C; Bellantoni, L; Bellavance, A; Benítez, J A; Beri, S B; Bernardi, G; Bernhard, R; Berntzon, L; Bertram, I; Besançon, M; Beuselinck, R; Bezzubov, V A; Bhat, P C; Bhatnagar, V; Binder, M; Biscarat, C; Black, K M; Blackler, I; Blazey, G; Blekman, F; Blessing, S; Bloch, D; Bloom, K; Blumenschein, U; Böhnlein, A; Boeriu, O; Bolton, T A; Borissov, G; Bos, K; Bose, T; Brandt, A; Brock, R; Brooijmans, G; Bross, A; Brown, D; Buchanan, N J; Buchholz, D; Bühler, M; Büscher, V; Burdin, S; Burke, S; Burnett, T H; Busato, E; Buszello, C P; Butler, J M; Calfayan, P; Calvet, S; Cammin, J; Caron, S; Carvalho, W; Casey, B C K; Cason, N M; Castilla-Valdez, H; Chakrabarti, S; Chakraborty, D; Chan, K M; Chandra, A; Charles, F; Cheu, E; Chevallier, F; Cho, D K; Choi, S; Choudhary, B; Christofek, L; Claes, D; Clement, B; Clément, C; Coadou, Y; Cooke, M; Cooper, W E; Coppage, D; Corcoran, M; Cousinou, M C; Cox, B; Crepe-Renaudin, S; Cutts, D; Cwiok, M; Da Motta, H; Das, A; Das, M; Davies, B; Davies, G; Davis, G A; De, K; de Jong, P; De Jong, S J; De La Cruz-Burelo, E; De Oliveira Martins, C; Degenhardt, J D; Déliot, F; Demarteau, M; Demina, R; Demine, P; Denisov, D; Denisov, S P; Desai, S; Diehl, H T; Diesburg, M; Doidge, M; Dominguez, A; Dong, H; Dudko, L V; Duflot, L; Dugad, S R; Duggan, D; Duperrin, A; Dyer, J; Dyshkant, A; Eads, M; Edmunds, D; Edwards, T; Ellison, J; Elmsheuser, J; Elvira, V D; Eno, S; Ermolov, P; Evans, H; Evdokimov, A; Evdokimov, V N; Fatakia, S N; Feligioni, L; Ferapontov, A V; Ferbel, T; Fiedler, F; Filthaut, F; Fisher, W; Fisk, H E; Fleck, I; Ford, M; Fortner, M; Fox, H; Fu, S; Fuess, S; Gadfort, T; Galea, C F; Gallas, E; Galyaev, E; García, C; García-Bellido, A; Gardner, J; Gavrilov, V; Gay, A; Gay, P; Gelé, D; Gelhaus, R; Gerber, C E; Gershtein, Yu; Gillberg, D; Ginther, G; Gollub, N; Gómez, B; Goussiou, A; Grannis, P D; Greenlee, H; Greenwood, Z D; Gregores, E M; Grenier, G; Gris, P; Grivaz, J F; Grünendahl, S; Grünewald, M W; Guo, F; Guo, J; Gutíerrez, G; Gutíerrez, P; Haas, A; Hadley, N J; Haefner, P; Hagopian, S; Haley, J; Hall, I; Hall, R E; Han, L; Hanagaki, K; Hansson, P; Harder, K; Harel, A; Harrington, R; Hauptman, J M; Hauser, R; Hays, J; Hebbeker, T; Hedin, D; Hegeman, J G; Heinmiller, J M; Heinson, A P; Heintz, U; Hensel, C; Herner, K; Hesketh, G; Hildreth, M D; Hirosky, R; Hobbs, J D; Hoeneisen, B; Hoeth, H; Hohlfeld, M; Hong, S J; Hooper, R; Houben, P; Hu, Y; Hubacek, Z; Hynek, V; Iashvili, I; Illingworth, R; Ito, A S; Jabeen, S; Jaffré, M; Jain, S; Jakobs, K; Jarvis, C; Jenkins, A; Jesik, R; Johns, K; Johnson, C; Johnson, M; Jonckheere, A; Jonsson, P; Juste, A; Käfer, D; Kahn, S; Kajfasz, E; Kalinin, A M; Kalk, J M; Kalk, J R; Kappler, S; Karmanov, D; Kasper, J; Kasper, P; Katsanos, I; Kau, D; Kaur, R; Kehoe, R; Kermiche, S; Khalatyan, N; Khanov, A; Kharchilava, A I; Kharzheev, Yu M; Khatidze, D; Kim, H; Kim, T J; Kirby, M H; Klima, B; Kohli, J M; Konrath, J P; Kopal, M; Korablev, V M; Kotcher, J; Kothari, B; Koubarovsky, A; Kozelov, A V; Krop, D; Kryemadhi, A; Kühl, T; Kumar, A; Kunori, S; Kupco, A; Kurca, T; Kvita, J; Lammers, S; Landsberg, G L; Lazoflores, J; Le Bihan, A C; Lebrun, P; Lee, W M; Leflat, A; Lehner, F; Lesne, V; Lévêque, J; Lewis, P; Li, J; Li, Q Z; Lima, J G R; Lincoln, D; Linnemann, J; Lipaev, V V; Lipton, R; Liu, Z; Lobo, L; Lobodenko, A; Lokajícek, M; Lounis, A; Love, P; Lubatti, H J; Lynker, M; Lyon, A L; Maciel, A K A; Madaras, R J; Mättig, P; Magass, C; Magerkurth, A; Magnan, A M; Makovec, N; Mal, P K; Malbouisson, H B; Malik, S; Malyshev, V L; Mao, H S; Maravin, Y; Martens, M; McCarthy, R; Meder, D; Melnitchouk, A; Mendes, A; Mendoza, L; Merkin, M; Merritt, K W; Meyer, A; Meyer, J; Michaut, M; Miettinen, H; Millet, T; Mitrevski, J; Molina, J; Mondal, N K; Monk, J; Moore, R W; Moulik, T; Muanza, G S; Mulders, M; Mulhearn, M; Mundal, O; Mundim, L; Mutaf, Y D; Nagy, E; Naimuddin, M; Narain, M; Naumann, N A; Neal, H A; Negret, J P; Neustroev, P; Nöding, C; Nomerotski, A; Novaes, S F; Nunnemann, T; O'Dell, V; O'Neil, D C; Obrant, G; Oguri, V; Oliveira, N; Onoprienko, D; Oshima, N; Otec, R; Oteroy-Garzon, G J; Owen, M; Padley, P; Parashar, N; Park, S J; Park, S K; Parsons, J; Partridge, R; Parua, N; Patwa, A; Pawloski, G; Perea, P M; Pérez, E; Peters, K; Petroff, P; Petteni, M; Piegaia, R; Piper, J; Pleier, M A; Podesta-Lerma, P L M; Podstavkov, V M; Pogorelov, Y; Pol, M E; Pompos, A; Pope, B G; Popov, A V; Potter, C; Prado da Silva, W L; Prosper, H B; Protopopescu, S D; Qian, J; Quadt, A; Quinn, B; Rangel, M S; Rani, K J; Ranjan, K; Ratoff, P N; Renkel, P; Reucroft, S; Rijssenbeek, M; Ripp-Baudot, I; Rizatdinova, F K; Robinson, S; Rodrigues, R F; Royon, C; Rubinov, P; Ruchti, R; Rud, V I; Sajot, G; Sánchez-Hernández, A; Sanders, M P; Santoro, A F S; Savage, G; Sawyer, L; Scanlon, T; Schaile, A D; Schamberger, R D; Scheglov, Y; Schellman, H; Schieferdecker, P; Schmitt, C; Schwanenberger, C; Schwartzman, A; Schwienhorst, R; Sekaric, J; Sen-Gupta, S; Severini, H; Shabalina, E; Shamim, M; Shary, V; Shchukin, A A; Shephard, W D; Shivpuri, R K; Shpakov, D; Siccardi, V; Sidwell, R A; Simák, V; Sirotenko, V I; Skubic, P L; Slattery, P F; Smith, R P; Snow, G R; Snow, J; Snyder, S; Söldner-Rembold, S; Song, X; Sonnenschein, L; Sopczak, A; Sosebee, M; Soustruznik, K; Souza, M; Spurlock, B; Stark, J; Steele, J; Stolin, V; Stone, A; Stoyanova, D A; Strandberg, J; Strandberg, S; Strang, M A; Strauss, M; Ströhmer, R; Strom, D; Strovink, M; Stutte, L; Sumowidagdo, S; Svoisky, P; Sznajder, A; Talby, M; Tamburello, P; Taylor, W; Telford, P; Temple, J; Tiller, B; Titov, M; Tokmenin, V V; Tomoto, M; Toole, T; Torchiani, I; Towers, S; Trefzger, T; Trincaz-Duvoid, S; Tsybychev, D; Tuchming, B; Tully, C; Turcot, A S; Tuts, P M; Unalan, R; Uvarov, L; Uvarov, S; Uzunyan, S; Vachon, B; vanden Berg, P J; Van Kooten, R; Van Leeuwen, W M; Varelas, N; Varnes, E W; Vartapetian, A H; Vasilyev, I A; Vaupel, M; Verdier, P; Vertogradov, L S; Verzocchi, M; Villeneuve-Séguier, F; Vint, P; Vlimant, J R; Von Törne, E; Voutilainen, M; Vreeswijk, M; Wahl, H D; Wang, L; Wang, M H L; Warchol, J; Watts, G; Wayne, M; Weber, G; Weber, M; Weerts, H; Wermes, N; Wetstein, M; White, A; Wicke, D; Wilson, G W; Wimpenny, S J; Wobisch, M; Womersley, J; Wood, D R; Wyatt, T R; Xie, Y; Xuan, N; Yacoob, S; Yamada, R; Yan, M; Yasuda, T; Yatsunenko, Y A; Yip, K; Yoo, H D; Youn, S W; Yu, C; Yu, J; Yurkewicz, A; Zatserklyaniy, A; Zeitnitz, C; Zhang, D; Zhao, T; Zhou, B; Zhu, J; Zielinski, M; Zieminska, D; Zieminski, A; Zutshi, V; Zverev, E G

    2006-01-01

    We report on a measurement of the $B^0_d$ mixing frequency and the calibration of an opposite-side flavor tagger in the D{\\O}experiment. Various properties associated with the $b$ quark on the opposite side of the reconstructed $B$ meson were combined using a likelihood-ratio method into a single variable with enhanced tagging power. Its performance was tested with data, using a large sample of reconstructed semileptonic $B \\to \\mu \\dzero X$ and $B \\to \\mu \\dst X$ decays, corresponding to an integrated luminosity of approximately 1 fb$^{-1}$. The events were divided into groups depending on the value of the combined tagging variable, and an independent analysis was performed in each group. Combining the results of these analyses, the overall effective tagging power was found to be eD^2 = (2.48 \\pm 0.21 (stat.) ^{+0.08}_{-0.06} (syst.))%. The measured $B^0_d$ mixing frequency dmd = 0.506 \\pm 0.020 {\\rm (stat) \\pm 0.016 (syst) ps}^{-1} is in good agreement with the world average value.

  11. Dual-sided microstructured semiconductor neutron detectors (DSMSNDs)

    Energy Technology Data Exchange (ETDEWEB)

    Fronk, Ryan G., E-mail: rfronk@ksu.edu [Mechanical and Nuclear Engineering Department, Kansas State University, Manhattan, KS 66506, United States (United States); Bellinger, Steven L.; Henson, Luke C. [Radiation Detection Technologies, Inc., Manhattan, KS 66502 (United States); Ochs, Taylor R.; Smith, Colten T.; Kenneth Shultis, J.; McGregor, Douglas S. [Mechanical and Nuclear Engineering Department, Kansas State University, Manhattan, KS 66506, United States (United States)

    2015-12-21

    Microstructured semiconductor neutron detectors (MSNDs) have in recent years received much interest as high-efficiency replacements for thin-film-coated thermal neutron detectors. The basic device structure of the MSND involves micro-sized trenches that are etched into a vertically-oriented pvn-junction diode that are backfilled with a neutron converting material. Neutrons absorbed within the converting material induce fission of the parent nucleus, producing a pair of energetic charged-particle reaction products that can be counted by the diode. The MSND deep-etched microstructures produce good neutron-absorption and reaction-product counting efficiencies, offering a 10× improvement in intrinsic thermal neutron detection efficiency over thin-film-coated devices. Performance of present-day MSNDs are nearing theoretical limits; streaming paths between the conversion-material backfilled trenches, allow a considerable fraction of neutrons to pass undetected through the device. Dual-sided microstructured semiconductor neutron detectors (DSMSNDs) have been developed that utilize a complementary second set of trenches on the back-side of the device to count streaming neutrons. DSMSND devices are theoretically capable of greater than 80% intrinsic thermal neutron detection efficiency for a 1-mm thick device. The first such prototype DSMSNDs, presented here, have achieved 29.48±0.29% nearly 2× better than MSNDs with similar microstructure dimensions.

  12. Development and Application of One-Sided Piezoelectric Actuating Micropump

    Directory of Open Access Journals (Sweden)

    H. K. Ma

    2013-01-01

    Full Text Available Three types of one-sided actuating piezoelectric micropumps are studied in this paper. In the first type, one-sided actuating micropump with two check valves can enhance the flow rate and prevent the back flow in suction mode to keep the flow in one direction. Furthermore, the frequency modulator is applied in the micropump to adjust and promote the maximum flow rate higher than 5.0 mL/s. In the second type, valveless micropump with secondary chamber shows that the secondary chamber plays a key role in the application of the valveless micropump. It not only keeps the flow in one direction but also makes the flow rate of the pump reach 0.989 mL/s. In addition, when a nozzle/diffuser element is used in valveless micropump, the flow rate can be further improved to 1.183 mL/s at a frequency of 150 Hz. In the third type, piezoelectric actuating pump is regarded as an air pump in the application of a microfuel cell system, which can increase more air inlet to improve the fuel/air reaction and further increase the performance of fuel cell.

  13. Deep Neural Network Based Demand Side Short Term Load Forecasting

    Directory of Open Access Journals (Sweden)

    Seunghyoung Ryu

    2016-12-01

    Full Text Available In the smart grid, one of the most important research areas is load forecasting; it spans from traditional time series analyses to recent machine learning approaches and mostly focuses on forecasting aggregated electricity consumption. However, the importance of demand side energy management, including individual load forecasting, is becoming critical. In this paper, we propose deep neural network (DNN-based load forecasting models and apply them to a demand side empirical load database. DNNs are trained in two different ways: a pre-training restricted Boltzmann machine and using the rectified linear unit without pre-training. DNN forecasting models are trained by individual customer’s electricity consumption data and regional meteorological elements. To verify the performance of DNNs, forecasting results are compared with a shallow neural network (SNN, a double seasonal Holt–Winters (DSHW model and the autoregressive integrated moving average (ARIMA. The mean absolute percentage error (MAPE and relative root mean square error (RRMSE are used for verification. Our results show that DNNs exhibit accurate and robust predictions compared to other forecasting models, e.g., MAPE and RRMSE are reduced by up to 17% and 22% compared to SNN and 9% and 29% compared to DSHW.

  14. Side-effects of protein kinase inhibitors on ion channels

    Indian Academy of Sciences (India)

    Youn Kyoung Son; Hongzoo Park; Amy L Firth; Won Sun Park

    2013-12-01

    Protein kinases are one of the largest gene families and have regulatory roles in all aspects of eukaryotic cell function. Modulation of protein kinase activity is a desirable therapeutic approach for a number of human diseases associated with aberrant kinase activity, including cancers, arthritis and cardiovascular disorders. Several strategies have been used to develop specific and selective protein kinase modulators, primarily via inhibition of phosphorylation and down-regulation of kinase gene expression. These strategies are effective at regulating intracellular signalling pathways, but are unfortunately associated with several undesirable effects, particularly those that modulate ion channel function. In fact, the side-effects have precluded these inhibitors from being both useful experimental tools and therapeutically viable. This review focuses on the ion channel side-effects of several protein kinase inhibitors and specifically on those modulating K+, Na+ and Ca2+ ion channels. It is hoped that the information provided with a detailed summary in this review will assist the future development of novel specific and selective compounds targeting protein kinases both for experimental tools and for therapeutic approaches.

  15. AISMIG—an interactive server-side molecule image generator

    Science.gov (United States)

    Bohne-Lang, Andreas; Groch, Wolf-Dieter; Ranzinger, René

    2005-01-01

    Using a web browser without additional software and generating interactive high quality and high resolution images of bio-molecules is no longer a problem. Interactive visualization of 3D molecule structures by Internet browsers normally is not possible without additional software and the disadvantage of browser-based structure images (e.g. by a Java applet) is their low resolution. Scientists who want to generate 3D molecular images with high quality and high resolution (e.g. for publications or to render a molecule for a poster) therefore require separately installed software that is often not easy to use. The alternative concept is an interactive server-side rendering application that can be interfaced with any web browser. Thus it combines the advantage of the web application with the high-end rendering of a raytracer. This article addresses users who want to generate high quality images from molecular structures and do not have software installed locally for structure visualization. Often people do not have a structure viewer, such as RasMol or Chime (or even Java) installed locally but want to visualize a molecule structure interactively. AISMIG (An Interactive Server-side Molecule Image Generator) is a web service that provides a visualization of molecule structures in such cases. AISMIG-URL: . PMID:15980568

  16. AISMIG--an interactive server-side molecule image generator.

    Science.gov (United States)

    Bohne-Lang, Andreas; Groch, Wolf-Dieter; Ranzinger, René

    2005-07-01

    Using a web browser without additional software and generating interactive high quality and high resolution images of bio-molecules is no longer a problem. Interactive visualization of 3D molecule structures by Internet browsers normally is not possible without additional software and the disadvantage of browser-based structure images (e.g. by a Java applet) is their low resolution. Scientists who want to generate 3D molecular images with high quality and high resolution (e.g. for publications or to render a molecule for a poster) therefore require separately installed software that is often not easy to use. The alternative concept is an interactive server-side rendering application that can be interfaced with any web browser. Thus it combines the advantage of the web application with the high-end rendering of a raytracer. This article addresses users who want to generate high quality images from molecular structures and do not have software installed locally for structure visualization. Often people do not have a structure viewer, such as RasMol or Chime (or even Java) installed locally but want to visualize a molecule structure interactively. AISMIG (An Interactive Server-side Molecule Image Generator) is a web service that provides a visualization of molecule structures in such cases. AISMIG-URL: http://www.dkfz-heidelberg.de/spec/aismig/.

  17. Antithyroid Drug Side Effects in the Population and in Pregnancy

    DEFF Research Database (Denmark)

    Andersen, Stine Linding; Olsen, Jørn; Laurberg, Peter

    2016-01-01

    OBJECTIVE: Methimazole (MMI) and Propylthiouracil (PTU) are both associated with birth defects, and may also rarely be associated with agranulocytosis and liver failure. The frequency of these side effects when antithyroid drugs (ATD) are used in the population in general or in pregnancy remains...... of agranulocytosis (1 in pregnancy) and 10 cases of liver failure (1 in pregnancy). This corresponded to 41/11 cases of agranulocytosis/liver failure per 5 million inhabitants during a 10-year period (agranulocytosis: 0.16% of ATD exposed (MMI: 0.11% vs. PTU: 0.27%, p=0.02); liver failure: 0.03% of ATD exposed (MMI......: 0.03% vs. PTU: 0.05%, p=0.4)). The majority (83%) developed the side effect within 3 months of ATD treatment, and 25% during hyperthyroidism relapse. The use of ATD in pregnancy was associated with birth defects in 3.4% of exposed children (44 cases/5 million inhabitants/10 years), and the frequency...

  18. Clinical Features of Right-sided Infective Endocarditis

    Institute of Scientific and Technical Information of China (English)

    杨莉; 伍卫; 王景峰; 张燕; 张小玲

    2002-01-01

    Objective To discuss thepathogenesis, etiology, clinical manifestations, diagnosis, treatment and prognosis of right-sided infective endocarditis (RIE) . Methods To investigate retrospectively the clinical data of patients with RIE admitted in our hospital from Jan 1985 to Dec 2000.Results There were 17 cases of RIE (12 male, 5female, mean age 22 years), among which 7 with congenital heart disease, 1 with pacemaker implantation and 9 with a history of intravenous drug abuse but without underlying heart disease. Fever and multiple pulmonary emboli were the major clinical manifestations. Blood cultures were positive in 8 cases with Staphylococcus aureus as the predominant microorganism. Echocardiography detected right heart vegetations in all cases, with tricuspid valve as the structure most frequently affected. Most patients were successfully treated with antimicrobials. The outcome was favourable, with a mortality of 11.8 % . Conclusions The clinical features of RIE are different from that of left-sided infective endocarditis (LIE) . Echocardiography plays an important role in the diagnosis of RIE.

  19. Experimental research on daylight performance of side lighting light pipe

    Institute of Scientific and Technical Information of China (English)

    WUYanpeng; MAChongfang

    2003-01-01

    Natural daylight has more and more been used in modem buildings to save building energy consumption in China. Light pipe is one of the effective way to reduce electricity consumption for lighting, it can transmit light from outdoor to the room without generating excessive heat. Experimental apparatus of side lighting light pipe is described in this paper. Light pipe for side daylighting purpose was installed in the Key Laboratory of Enhanced Heat Transfer and Energy Conservation, Ministry of Education, Beijing University of Technology. It was 2.6m long, with diameters of 360mm.The performance of the light pipe for whole day had been measured. The highest iUuminance was 488lux on Dec.26,2002, obtained from the point beneath the center of the diffuser of the light pipe 1450mm. The ratio of internal illuminance to external was 0.23 %. Because it has many advantages to improve energy efficiency in buildings, light pipe will be populanzed in the near future in China.

  20. Advancing the Power and Utility of Server-Side Aggregation

    Science.gov (United States)

    Fulker, Dave; Gallagher, James

    2016-01-01

    During the upcoming Summer 2016 meeting of the ESIP Federation (July 19-22), OpenDAP will hold a Developers and Users Workshop. While a broad set of topics will be covered, a key focus is capitalizing on recent EOSDIS-sponsored advances in Hyrax, OPeNDAPs own software for server-side realization of the DAP2 and DAP4 protocols. These Hyrax advances are as important to data users as to data providers, and the workshop will include hands-on experiences of value to both. Specifically, a balanced set of presentations and hands-on tutorials will address advances in1.server installation,2.server configuration,3.Hyrax aggregation capabilities,4.support for data-access from clients that are HTTP-based, JSON-based or OGC-compliant (especially WCS and WMS),5.support for DAP4,6.use and extension of server-side computational capabilities, and7.several performance-affecting matters.Topics 2 through 7 will be relevant to data consumers, data providers andnotably, due to the open-source nature of all OPeNDAP softwareto developers wishing to extend Hyrax, to build compatible clients and servers, andor to employ Hyrax as middleware that enables interoperability across a variety of end-user and source-data contexts. A session for contributed talks will elaborate the topics listed above and embrace additional ones.

  1. Characterisation of the Optical Turbulence at Siding Spring

    CERN Document Server

    Goodwin, Michael; Lambert, Andrew

    2012-01-01

    Measurements of the optical turbulence profile above Siding Spring Observatory were conducted during 2005 and 2006. This effort was largely motivated by the need to predict the statistical performance of adaptive optics at Siding Spring. The data were collected using a purpose-built instrument based on the slope-detection and ranging method (SLODAR) where observations of a bright double star are imaged by Shack-Hartmann taken with the Australian National University 24 inch and 40 inch telescopes. The analysis of the data yielded a model consisting of a handful of statistically prominent thin layers that are statistically separated into the ground layer (37.5, 250m) and the free atmosphere (1, 3, 6, 9, 13.5 km) for good (25%), typical (50%) and bad (25%) observing conditions. We found that ground-layer turbulence dominates the turbulence profile with up to 80% of the integrated turbulence below 500 m. The turbulence tends to be non-Kolmogorov, especially for the ground-layer with a power law index of $\\beta \\s...

  2. An assessment of gas-side fouling in cement plants

    Science.gov (United States)

    Marner, W. J.

    1982-01-01

    The cement industry is the most energy-intensive industry in the United States in terms of energy cost as a percentage of the total product cost. An assessment of gas-side fouling in cement plants with special emphasis on heat recovery applications is provided. In the present context, fouling is defined as the buildup of scale on a heat-transfer surface which retards the transfer of heat and includes the related problems of erosion and corrosion. Exhaust gases in the cement industry which are suitable for heat recovery range in temperature from about 100 to 1300 K, are generally dusty, may be highly abrasive, and are often heavily laden with alkalies, sulfates, and chlorides. Particulates in the exhaust streams range in size from molecular to about 100 micrometers in diameter and come from both the raw feed as well as the ash in the coal which is the primary fuel used in the cement industry. The major types of heat-transfer equipment used in the cement industry include preheaters, gas-to-air heat exchangers, waste heat boilers, and clinker coolers. At the present time, the trend in this country is toward suspension preheater systems, in which the raw feed is heated by direct contact with the hot kiln exit gases, and away from waste heat boilers as the principal method of heat recovery. The most important gas-side fouling mechanisms in the cement industry are those due to particulate, chemical reaction, and corrosion fouling.

  3. Fractionation of proteins with two-sided electro-ultrafiltration.

    Science.gov (United States)

    Käppler, Tobias; Posten, Clemens

    2007-03-10

    Downstream processing is a major challenge in bioprocess industry due to the high complexity of bio-suspensions itself, the low concentration of the product and the stress sensitivity of the valuable target molecules. A multitude of unit operations have to be joined together to achieve an acceptable purity and concentration of the product. Since each of the unit operations leads to a certain product loss, one important aim in downstream-research is the combination of different separation principles into one unit operation. In the current work a dead-end membrane process is combined with an electrophoresis operation. In the past this concept has proven successfully for the concentration of biopolymers. The present work shows that using different ultrafiltration membranes in a two-sided electro-filter apparatus with flushed electrodes brought significant enhancement of the protein fractionation process. Due to electrophoretic effects, the filtration velocity could be kept on a very high level for a long time, furthermore, the selectivity of a binary separation process carried out exemplarily for bovine serum albumin (BSA) and lysozyme (LZ) could be greatly increased; in the current case up to a value of more than 800. Thus the new two-sided electro-ultrafiltration technique achieves both high product purity and short separation times.

  4. Front-Side Microstrip Line Feeding a Raised Antenna Patch

    Science.gov (United States)

    Hodges, Richard; Hoppe, Daniel

    2005-01-01

    An improved design concept for a printed-circuit patch antenna and the transmission line that feeds the patch calls for (1) a microstrip transmission line on the front (radiative) side of a printed-circuit board based on a thin, high-permittivity dielectric substrate; (2) using the conductor covering the back side of the circuit board as a common ground plane for both the microstrip line and the antenna patch; (3) supporting the antenna patch in front of the circuit board on a much thicker, lower-permittivity dielectric spacer layer; and (4) connecting the microstrip transmission line to the patch by use of a thin wire or narrow ribbon that extends through the thickness of the spacer and is oriented perpendicularly to the circuit-board plane. The thickness of the substrate is typically chosen so that a microstrip transmission line of practical width has an impedance between 50 and 100 ohms. The advantages of this design concept are best understood in the context of the disadvantages of prior design concepts, as explained

  5. Slipping during side-step cutting: anticipatory effects and familiarization.

    Science.gov (United States)

    Oliveira, Anderson Souza Castelo; Silva, Priscila Brito; Lund, Morten Enemark; Farina, Dario; Kersting, Uwe Gustav

    2014-04-01

    The aim of the present study was to verify whether the expectation of perturbations while performing side-step cutting manoeuvres influences lower limb EMG activity, heel kinematics and ground reaction forces. Eighteen healthy men performed two sets of 90° side-step cutting manoeuvres. In the first set, 10 unperturbed trials (Base) were performed while stepping over a moveable force platform. In the second set, subjects were informed about the random possibility of perturbations to balance throughout 32 trials, of which eight were perturbed (Pert, 10cm translation triggered at initial contact), and the others were "catch" trials (Catch). Center of mass velocity (CoMVEL), heel acceleration (HAC), ground reaction forces (GRF) and surface electromyography (EMG) from lower limb and trunk muscles were recorded for each trial. Surface EMG was analyzed prior to initial contact (PRE), during load acceptance (LA) and propulsion (PRP) periods of the stance phase. In addition, hamstrings-quadriceps co-contraction ratios (CCR) were calculated for these time-windows. The results showed no changes in CoMVEL, HAC, peak GRF and surface EMG PRE among conditions. However, during LA, there were increases in tibialis anterior EMG (30-50%) concomitant to reduced EMG for quadriceps muscles, gluteus and rectus abdominis for Catch and Pert conditions (15-40%). In addition, quadriceps EMG was still reduced during PRP (pmodulation of muscle activity towards anticipating potential instability in the lower limb joints and assure safety to complete the task.

  6. Interaction of a hot jet with two cold side jets

    Directory of Open Access Journals (Sweden)

    Nouali Nassira

    2015-01-01

    Full Text Available Spreading of the multijet in terms of both the velocity and temperature field depends strongly on the flow type related to the velocity and temperature ratios between the cold side jets to the hot central one. This is the reason why the present work focuses on numerical investigation of non isothermal three parallel non-ventilated turbulent plane jets. As well, it seems natural to pick as reference the available experimental data. The numerical predictions confirm the three types (A, B, C of flow patterns given by the available flow visualization and reveal a fourth that will be called type D. The purpose of the present study is to explore the effect of the velocity ratio on the decay rates of the velocity and temperature in the fully developed region. It is found that the addition of side jets increase the rate of decrease of the centerline velocity for the flow of type A and decreases in the other cases. The effect of various types of flow on the rate of decrease of the velocity and the temperature in the fully developed flow region are investigated in details: This led to establish several correlations of the rate of decrease that play an important role in the diffusion of momentum and temperature.

  7. Phytochemicals that counteract the cardiotoxic side effects of cancer chemotherapy

    Directory of Open Access Journals (Sweden)

    Anita Piasek

    2009-04-01

    Full Text Available Almost all clinically used antitumor drugs exhibit toxic side effects affecting heart function. Because of cardiotoxicity during anticancer chemotherapy, effective doses of cytostatics have to be limited, which may worsen antitumor efficacy. The cardiotoxicity induced by cytostatics of the anthracycline group in particular results, among others, from massive stimulation of ROS. It has therefore been suggested that some phytochemicals with high antioxidant potential, when administered together with antitumor agents, could decrease the toxic side effects of chemotherapy and reduce the risk of heart failure. This review summarizes findings of studies undertaken to identify edible plants or phytochemicals isolated from them displaying cardioprotective properties during chemotherapy. Such properties have been shown for such foods as grapes, garlic, tomato, spinach, and beetroot. A protective role on the heart is also displayed by melatonin (a hormone synthesized by the pineal gland, but also present in many edible plants, chalcones (precursors of all known flavonoids, some herbal dietary supplements, vitamins A, C, and E, selenium, and semisynthetic flavonoid 7-monohydroxyethylrutoside (monoHER. Although to date only a limited number of investigations have been carried out, their results suggest that dietary intervention with antioxidants found in edible plants may be a safe and effective way of alleviating the toxicity of anticancer chemotherapy and preventing heart failure.

  8. Wide spread spectrum watermarking with side information and interference cancellation

    CERN Document Server

    Guelvouit, Gaëtan Le; 10.1117/12.476839

    2008-01-01

    Nowadays, a popular method used for additive watermarking is wide spread spectrum. It consists in adding a spread signal into the host document. This signal is obtained by the sum of a set of carrier vectors, which are modulated by the bits to be embedded. To extract these embedded bits, weighted correlations between the watermarked document and the carriers are computed. Unfortunately, even without any attack, the obtained set of bits can be corrupted due to the interference with the host signal (host interference) and also due to the interference with the others carriers (inter-symbols interference (ISI) due to the non-orthogonality of the carriers). Some recent watermarking algorithms deal with host interference using side informed methods, but inter-symbols interference problem is still open. In this paper, we deal with interference cancellation methods, and we propose to consider ISI as side information and to integrate it into the host signal. This leads to a great improvement of extraction performance ...

  9. Dual-sided microstructured semiconductor neutron detectors (DSMSNDs)

    Science.gov (United States)

    Fronk, Ryan G.; Bellinger, Steven L.; Henson, Luke C.; Ochs, Taylor R.; Smith, Colten T.; Kenneth Shultis, J.; McGregor, Douglas S.

    2015-12-01

    Microstructured semiconductor neutron detectors (MSNDs) have in recent years received much interest as high-efficiency replacements for thin-film-coated thermal neutron detectors. The basic device structure of the MSND involves micro-sized trenches that are etched into a vertically-oriented pvn-junction diode that are backfilled with a neutron converting material. Neutrons absorbed within the converting material induce fission of the parent nucleus, producing a pair of energetic charged-particle reaction products that can be counted by the diode. The MSND deep-etched microstructures produce good neutron-absorption and reaction-product counting efficiencies, offering a 10× improvement in intrinsic thermal neutron detection efficiency over thin-film-coated devices. Performance of present-day MSNDs are nearing theoretical limits; streaming paths between the conversion-material backfilled trenches, allow a considerable fraction of neutrons to pass undetected through the device. Dual-sided microstructured semiconductor neutron detectors (DSMSNDs) have been developed that utilize a complementary second set of trenches on the back-side of the device to count streaming neutrons. DSMSND devices are theoretically capable of greater than 80% intrinsic thermal neutron detection efficiency for a 1-mm thick device. The first such prototype DSMSNDs, presented here, have achieved 29.48±0.29% nearly 2× better than MSNDs with similar microstructure dimensions.

  10. CORTICAL CLEANUP WITHOUT SIDE PORT IN SMALL INCISION CATARACT SURGERY

    Directory of Open Access Journals (Sweden)

    Udaya Kumar

    2015-11-01

    Full Text Available The aim of study was to achieve complete cortical cleanup and avoid problems related with sideport during Small Incision Cataract Surgery (SICS so as to have a good visual out come with minimal recovery period, and a better quality of life. After nucleus delivery, cortical cleanup is an important step in any cataract surgical procedure. Cortex especially subincisional area (11 to 1 o’clock is difficult to manage intraoperatively. Bimanual irrigation aspiration through two side ports, aspiration by J cannula, iris massage manoeuver, ice cream scoop manoeuver are various techniques of cortical matter aspiration. We acquired the technique of aspiration of subincisional cortex without using side port in all cases by paying attention on type of cataract, status of pupil, use of Adrenalin mixed BSS intraoperatively, Tunnel construction, Capsulorhexis size and capsular rim size at 12 o’clock. MATERIAL AND METHODS In this retrospective study of 1 year from 2013 to 2014, 60 patients (60 eyes aged 40 years or older attending the General Ophthalmic Department were included in the study group with another group of 60 patients (60 eyes as controls. The study was on age related cataracts which are basically. 1 Cortical cataract 2 Nuclear cataract 3 Subcapsular cataract. Proper assessment of cortical cataract based on its maturity such as a Immature b Mature c Hyper mature and d Morgagnian cataract, nucleus for its opalescence and color, size of posterior subcapsular opacity and pupillary status (Dilating well or not with mydriatics were taken into consideration. Eyes with pseudoexfoliation having poor pupillary dilation were also included. Eyes with congenital anomalies, congenital cataract, gross corneal and retinal pathologies, and glaucoma were excluded. RESULTS Among 60 study eyes in the study group 35 presented with cortical, 20 with nuclear cataract and 5 with posterior subcapsular cataracts. In 58(96.6% cases, sideport was not required; 3(5% eyes

  11. Study on mechanism of reinforcing sides to control floor heave of extraction opening

    Institute of Scientific and Technical Information of China (English)

    FENG Tao

    2005-01-01

    Roadway surrounding rock is a compound structure consisted of roof, floor and sides. The sides of extraction opening is the weak coal mass, which affect immediately the stability of floor. It was simulated by numerical calculation for the strength of sides coal to affect the floor heave, the higher strength of sides coal is, the lower degree of floor heave was. So it was put forward reinforcing sides to control floor heave of extraction opening,and it was proved by engineering practice that the floor heave of deep extraction opening can be controlled to a certain degree by reinforcing sides of roadway.

  12. Efficacy of semielevated side-lying positioning during bottle-feeding of very preterm infants: a pilot study.

    Science.gov (United States)

    Park, Jinhee; Thoyre, Suzanne; Knafl, George J; Hodges, Eric A; Nix, William B

    2014-01-01

    Very preterm (VP, ≤30 wk gestational age) infants are at risk for impaired lung function, which significantly limits their ability to eat. A semielevated side-lying (ESL) position is a feeding strategy that may improve oral feeding by supporting breathing during feeding. The study evaluated the efficacy of the ESL position compared with the semielevated supine (ESU) position on physiological stability and feeding performance of bottle-fed VP infants. Using a within-subject crossover design, 6 VP infants were bottle-fed twice on 1 day, in both the ESL and ESU positions in a random order. Physiological stability (heart rate, oxygen saturation [SaO2], and respiratory characteristics) and feeding performance (percent intake, proficiency, efficiency, and duration of feeding) were measured before and/or during feeding. Very preterm infants fed in the ESL position demonstrated significantly less variation in heart rate, less severe and fewer decreases in heart rate, respiratory rate that was closer to the prefeeding state, shorter and more regular intervals between breaths, and briefer feeding-related apneic events. No significant differences for SaO2 or feeding performance were found. The findings indicate that the ESL position may support better regulation of breathing during feeding, thereby allowing VP infants to better maintain physiological stability throughout feeding.

  13. Properties of the flow around two rotating circular cylinders in side-by-side arrangement with different rotation types

    Directory of Open Access Journals (Sweden)

    Tu Cheng-Xu

    2014-01-01

    Full Text Available The field characteristics of two side-by-side rotating circular cylinders in a cross-flow is investigated under different rotation types, at T/D = 1.11,1.6, and 3, respectively (T is the center spacing between the cylinders, and D is the cylinder diameter. A similar flow pattern which is the most efficient to narrow the lowpressure area is identified for rotation type A, independent of T/D ratio, and two typical flow patterns are found under different spacings for rotation type B and type C, respectively. It is confirmed that there is an optimal rotational speed of 1.7-2, under rotation type A to attenuate the vortices, velocity drop, and turbulence intensity tremendously. As rotational speed increases to the optimal value, both the velocity drop and turbulence intensity decrease and their distributions are smooth. The results indicate that the shear layers which are accelerated following the free-stream direction would have significant influence on the flow modification, and different rotation types actually arrange these shear layers in diverse ways to change the flow pattern. Pitch ratio is capable to transform the gap flow, which is usually including the shear layers referred, thus this parameter can modify the wake of the two cylinders at different rotation types.

  14. Combined side-to-end anastomosis with temporary end colostomy for the management of selected left-sided colonic emergencies.

    Science.gov (United States)

    Safioleas, Michael; Stamatakos, Michael; Safioleas, Panayoitis; Safioleas, Konstantinos; Sakorafas, George H

    2011-04-01

    Management of surgical emergencies of the left colon commonly requires excision of the colonic segment bearing the lesion, creation of an end colostomy, and closure of the rectosigmoid stump. Closure of the end stoma may be technically challenging. During this study, we used a new surgical technique involving the creation of an end-to-side anastomosis of the rectosigmoid stump to the base of the proximal colonic segment in association with an end colostomy. During a 15-year period, 23 patients were offered this type of surgery. Mortality was zero. Complications were observed in seven patients (morbidity, 7/23). Mean hospitalization time was 12.3 days. Closure of the colostomy was performed approximately 1 month after initial surgery and was easily performed using a mechanical stapler, either intraperitoneally or even extraperitoneally. No complications were observed after closure of the colostomy. The described technique is a useful alternative for the management of selected patients with left-sided colonic surgical emergencies. Its main advantage is that it greatly facilitates colostomy closure, which is performed earlier compared with the colostomy closure after a typical Hartmann's procedure.

  15. Vortex Structures and Behavior of a Flow Past Two Rotating Circular Cylinders Arranged Side-by-Side

    Institute of Scientific and Technical Information of China (English)

    GUO Xiao-Hui; LIN Jian-Zhong; NIE De-Ming

    2009-01-01

    We present a study on the vortex structures and behavior of a Sow past two rotating circular cylinders arranged side-by-side at a range of absolute rotational speeds (|a| ≤ 2) for two different gap spacings g* = 1.5 and 0.7 at Reynolds numbers Re = 160 and 200. The results show that the flow becomes stabilized and finally steady beyond the critical rotational speed as|a| increases, regardless of the variation in Re and g". The value of critical rotational speed increases with increasing Re. The wake patterns change in the unsteady regimes for g* = 1.5 and 0.7. With increasing|a|, the time-averaged drag coefficient Cd decreases and the lift coefficient Cl increases, respectively. Cp at Re = 160 and g* = 0.7 decreases rapidly, resulting in the smallest value at the same |a| for 1 ≤ |a|≤ 2. Cd augments with increasing g* at the same|a|. For g* = 1.5, Cd has a little disparity between the cases of Re = 160 and 200. For the How past two still cyhnders, (C)L is inversely proportional to g* of two cylinders for a fixed |a|, and is not dependent on Re.

  16. Unsteady Performance of Finite-Span Pitching Propulsors in Mixtures of Side-by-Side and In-Line Arrangements

    Science.gov (United States)

    Kurt, Melike; Moored, Keith

    2016-11-01

    Birds, insects, and fish propel themselves by flapping their wings or oscillating their fins in unsteady motions. Many of these animals fly or swim in groups or collectives, typically described as flocks, swarms and schools. The three-dimensional steady flow interactions and the two dimensional unsteady flow interactions that occur in collectives are well characterized. However, the interactions that occur among three-dimensional unsteady propulsors remain relatively unexplored. The aim of the current study is to measure the forces acting on and the energetics of two finite-span pitching wings. The wings are arranged in mixtures of canonical in-line and side-by-side configurations while the phase delay between the pitching wings is varied. The thrust force, fluid-mediated interaction force between the wings and the propulsive efficiency are quantified. The three-dimensional interaction mechanisms are compared and contrasted with previously examined two-dimensional mechanisms. Stereoscopic particle image velocimetry is employed to characterize the three-dimensional flow structures along the span of the pitching wings.

  17. Dynamic interference of two anti-phase flapping foils in side-by-side arrangement in an incompressible flow

    Science.gov (United States)

    Bao, Y.; Zhou, D.; Tao, J. J.; Peng, Z.; Zhu, H. B.; Sun, Z. L.; Tong, H. L.

    2017-03-01

    A two-dimensional computational hydrodynamic model is developed to investigate the propulsive performance of a flapping foil system in viscous incompressible flows, which consists of two anti-phase flapping foils in side-by-side arrangement. In the simulations, the gap between the two foils is varied from 1.0 to 4.0 times of the diameter of the semi-circular leading edge; the amplitude-based Strouhal number is changed from 0.06 to 0.55. The simulations therefore cover the flow regimes from negligible to strong interference in the wake flow. The generations of drag and thrust are investigated as well. The numerical results reveal that the counter-phase flapping motion significantly changes the hydrodynamic force generation and associated propulsive wake. Furthermore, the wake interference becomes important for the case with a smaller foil-foil gap and induces the inverted Bénard von Kármán vortex streets. The results show that the hydrodynamic performance of two anti-phase flapping foils can be significantly different from an isolated pitching foil. Findings of this study are expected to provide new insight for developing hydrodynamic propulsive systems by improving the performance based on the foil-foil interaction.

  18. Security Issues of Solar Energy Harvesting Road Side Unit (RSU

    Directory of Open Access Journals (Sweden)

    Qutaiba I. Ali

    2015-06-01

    Full Text Available Vehicular network security had spanned and covered a wide range of security related issues. Howeversolar energy harvesting Road Side Unit (RSU security was not defined clearly, it is this aspect that is considered in this paper. In this work, we will suggest an RSU security model to protect it against different internal and external threats. The main goal is to protect RSU specific data (needed for its operation as well as its functionality and accessibility. The suggested RSU security model must responds to many objectives, it should ensure that the administrative information exchanged is correct and undiscoverable (information authenticity and privacy, the source (e.g., VANET server is who he claims to be (message integrity and source authentication and the system is robust and available (using Intrusion Detection System (IDS. In this paper, we suggest many techniques to strength RSU security and they were prototyped using an experimental model based on Ubicom IP2022 network processor development kit .

  19. Robust Watermarking Scheme with Side Information and Template Matching Mechanism

    Institute of Scientific and Technical Information of China (English)

    Guo Jie(郭捷); Fang Tao; Shi Pengfei

    2004-01-01

    Digital watermarking has been proposed for the copyright protections of multimedia products. In this paper, a robust and blind watermarking scheme is presented. The concept of communication with side information is applied at the encoder to improve the probability of detection within acceptable fidelity, while the template matching technique is employed to estimate the undergone attacks in attacking channel. This scheme is optimized by the optimal design of the encoder to match with the media content and the decoder to adapt to the attack channel state. Experiments show that our method is robust against some common attacks such as filtering, compression, rotation, scaling, cropping and translation. It can be applied to both color and gray images.

  20. [Treatment of endometriosis by aromatase inhibitors: efficacy and side effects].

    Science.gov (United States)

    Racine, A-C; Legrand, E; Lefebvre-Lacoeuille, C; Hoppe, E; Catala, L; Sentilhes, L; Descamps, P

    2010-05-01

    The recent demonstration that aromatase is expressed at higher levels in endometriosis implants than in normal endometrium has led to pilot studies using inhibitor aromatasis in patients with endometriosis. We conducted a systematic review of the literature and studied the efficacy of aromatase inhibitors on endometriosis. There were seventeen studies (case reports/series) evaluating outcomes of aromatase inhibitors. Studies suggest that aromatase inhibitors alone or co-administered with progestins, oral contraceptives or gonadotrophin releasing hormone (GnRH) agonist could reduce pain and endometriosis. There is only one randomized controlled trial comparing aromatase inhibitor+GnRH agonist and GnRH agonist and one study with eighty patients. Side-effects profiles of aromatase inhibitor regimens are favorable; it does not appear a significant bone loss. Aromatase inhibitors seem to have a promising effect on endometriosis but randomized controlled trials are needed to prove their effects and their safety.

  1. The other side of the histamine H3 receptor.

    Science.gov (United States)

    Ellenbroek, Bart A; Ghiabi, Bibinaz

    2014-04-01

    Although histamine H3 receptors are predominantly known as presynaptic receptors, regulating the release of neurotransmitters such as dopamine, acetylcholine, and histamine, in the striatal complex the vast majority of these receptors are actually located on the other side, in other words postsynaptically. Given their strategic location, they can crucially affect signaling throughout the basal ganglia. We describe the anatomy and function of H3 receptors within the basal ganglia with a specific focus on their colocalization with dopamine D1 and D2 receptors. Because the basal ganglia are centrally involved in several major neurological and psychiatric disorders, we also discuss the therapeutic potential of drugs targeting H3 receptors in the treatment of Parkinson disease (PD), schizophrenia, and addiction.

  2. Measles Vaccine : A Study On Seroconversion And Side Effects

    Directory of Open Access Journals (Sweden)

    Malik Abida

    1998-01-01

    Full Text Available Research Question: 1. What is the extent of immune response of Edmonston Zagreb Strain in children? 2. What are the side effects of this vaccine? Objectives: 1. To follow up children after Edmonston Zagreb strain vaccination for evaluation of seroconverstion. Study: Cross sectional Setting: Well Baby Clinic of pediatrics OPD at J.N. Medical College, A.M.U., Aigarh (U.P participants: Children between 9-15 months. Sample Size: 100 consecutive children coming for routine immunization. Study variable: Malnourished and poor socio-economic status Outcome variable: Extent of seroconversion with no statistical significant difference between malnourished and socio-economically poor children. 26% showed minor self-limiting post vaccination reactions in all age groups. Recommendations: Edmonston Zagreb measles vaccine is recommended since it has very good immunogenic activity and post vaccination reactions.

  3. Left-sided omental torsion with inguinal hernia

    Institute of Scientific and Technical Information of China (English)

    Yasumitsu Hirano; Kaeko Oyama; Hiroshi Nozawa; Takuo Hara; Koichi Nakada; Masahiro Hada; Takeshi Takagi; Makoto Hirano

    2006-01-01

    We report a case of surgically proved left-sided torsion of the greater omentum that caused secondary by untreated inguinal hernia. Case A 36-year-old man presented to our hospital with abdominal pain. He had been diagnosed with a left inguinal hernia, but he had not received any treatments. Contrast-enhanced computed tomography (CT) of the abdomen showed a large fat density mass below the Sigmoid colon and left inguinal hernia with incarcerated fat. Exploratory laparotomy revealed torsion of the greater omentum with small bloody ascites. The greater omentum was twisted into one and a half circles and entered into a left inguinal hernia. An omentectomy with a repair of left inguinal hernia was performed. A resected omentum was submitted for pathological examination, which showed hemorrhagic infarction. Omental torsion is a rare cause of acute abdominal pain but should be included in the differential diagnoses of acute abdomen, especially in patients with untreated inguinal hernia.

  4. An Efficient Method against Side-Channel Attacks on ECC

    Institute of Scientific and Technical Information of China (English)

    LIU Shuanggen; HU Yupu; XU Wensheng

    2006-01-01

    Side-channel attacks(SCA) may exploit leakage information to break cryptosystems. In this paper we present a new SCA resistant Elliptic Curve scalar multiplication algorithm. The proposed algorithm, builds a sequence of bit-strings representing the scalar k, characterized by the fact that all bit-strings are different from zero; this property will ensure a uniform computation behavior for the algorithm, and thus will make it secure against simple power analysis attacks(SPA). With other randomization techniques, the proposed countermeasures do not penalize the computation time. The proposed scheme is more efficient than M(O)ller' one, its cost being about 5% to 10% smaller than M(O)ller' one.

  5. The T2K Side Muon Range Detector (SMRD)

    Energy Technology Data Exchange (ETDEWEB)

    Aoki, S. [Kobe University, Department of Physics (Japan); Barr, G. [University of Oxford, Department of Physics, Oxford (United Kingdom); Batkiewicz, M.; Błocki, J. [H. Niewodniczański Institute of Nuclear Physics PAN, Kraków (Poland); Brinson, J.D.; Coleman, W. [Louisiana State University, Department of Physics and Astronomy, Baton Rouge, LA (United States); Dąbrowska, A. [H. Niewodniczański Institute of Nuclear Physics PAN, Kraków (Poland); Danko, I. [University of Pittsburgh, Department of Physics and Astronomy, Pittsburgh, PA (United States); Dziewiecki, M. [Warsaw University of Technology, Institute of Radioelectronics, Warsaw (Poland); Ellison, B. [Louisiana State University, Department of Physics and Astronomy, Baton Rouge, LA (United States); Golyshkin, L. [Institute for Nuclear Research, Moscow (Russian Federation); Gould, R. [Louisiana State University, Department of Physics and Astronomy, Baton Rouge, LA (United States); Hara, T. [Kobe University, Department of Physics (Japan); Haremza, J.; Hartfiel, B. [Louisiana State University, Department of Physics and Astronomy, Baton Rouge, LA (United States); Holeczek, J. [University of Silesia, Institute of Physics, Katowice (Poland); Izmaylov, A.; Khabibullin, M.; Khotjantsev, A. [Institute for Nuclear Research, Moscow (Russian Federation); Kiełczewska, D. [University of Warsaw, Institute of Experimental Physics, Warsaw (Poland); and others

    2013-01-11

    The T2K experiment is a long baseline neutrino oscillation experiment aiming to observe the appearance of ν{sub e} in a ν{sub μ} beam. The ν{sub μ} beam is produced at the Japan Proton Accelerator Research Complex (J-PARC), observed with the 295 km distant Super-Kamiokande Detector and monitored by a suite of near detectors at 280 m from the proton target. The near detectors include a magnetized off-axis detector (ND280) which measures the unoscillated neutrino flux and neutrino cross-sections. The present paper describes the outermost component of ND280 which is a Side Muon Range Detector (SMRD) composed of scintillation counters with embedded wavelength shifting fibers and Multi-Pixel Photon Counter readout. The components, performance and response of the SMRD are presented.

  6. Joint Encryption and Compression of Correlated Sources with Side Information

    Directory of Open Access Journals (Sweden)

    Haleem MA

    2007-01-01

    Full Text Available We propose a joint encryption and compression (JEC scheme with emphasis on application to video data. The proposed JEC scheme uses the philosophy of distributed source coding with side information to reduce the complexity of the compression process and at the same time uses cryptographic principles to ensure that security is built into the scheme. The joint distributed compression and encryption is achieved using a special class of codes called high-diffusion (HD codes that were proposed recently in the context of joint error correction and encryption. By using the duality between channel codes and Slepian-Wolf coding, we construct a joint compression and encryption scheme that uses these codes in the diffusion layer. We adapt this cipher to MJPEG2000 with the inclusion of minimal amount of joint processing of video frames at the encoder.

  7. Heterogeneities in gelatin film formation using single-sided NMR.

    Science.gov (United States)

    Ghoshal, Sushanta; Mattea, Carlos; Denner, Paul; Stapf, Siegfried

    2010-12-16

    Gelatin solutions were prepared in D(2)O. The drying process of cast solutions was followed with a single-sided nuclear magnetic resonance (NMR) scanner until complete solidification occurred. Spin-spin relaxation times (T(2)) were measured at different layers with microscopic resolution and were correlated with the drying process during film formation. Additionally, the evaporation of the gelatin solution was observed optically from the reduction of the sample thickness, revealing that at the macroscopic level, the rate of evaporation is not uniform throughout the experiment. A crossover in the spatial evolution of the drying process is observed from the NMR results. At the early stages, the gel appears to be drier in the upper layers near the evaporation front, while this tendency is inverted at the later stages, when drying is faster from the bottom. XRD (X-ray diffraction) data showed that a structural heterogeneity persists in the final film.

  8. Side-gated ultrathin-channel nanopore FET sensors.

    Science.gov (United States)

    Yanagi, Itaru; Oura, Takeshi; Haga, Takanobu; Ando, Masahiko; Yamamoto, Jiro; Mine, Toshiyuki; Ishida, Takeshi; Hatano, Toshiyuki; Akahori, Rena; Yokoi, Takahide; Anazawa, Takashi

    2016-03-18

    A side-gated, ultrathin-channel nanopore FET (SGNAFET) is proposed for fast and label-free DNA sequencing. The concept of the SGNAFET comprises the detection of changes in the channel current during DNA translocation through a nanopore and identifying the four types of nucleotides as a result of these changes. To achieve this goal, both p- and n-type SGNAFETs with a channel thicknesses of 2 or 4 nm were fabricated, and the stable transistor operation of both SGNAFETs in air, water, and a KCl buffer solution were confirmed. In addition, synchronized current changes were observed between the ionic current through the nanopore and the SGNAFET's drain current during DNA translocation through the nanopore.

  9. Electrical properties of the sensitive side in Si edgeless detectors

    CERN Document Server

    Verbitskaya, E; Eremin, I; Ilyashenko, I; Cavallini, A; Castaldini, A; Pellegrini, G; Lozano, M; Golubkov, S; Egorov, N; Konkov, K; Tuuva, T

    2009-01-01

    Silicon edgeless detectors represent a novel type of detector that are being developed for close-to-beam applications in high-energy physics and for large-scale tiled 1D and 2D arrays used in radiation imaging. In this work, the electric field and potential distributions on the device cut side, key factors in detector performance, have been investigated using two methods—the Conductive Microprobe Technique and the Scanning Transient Current Technique. It has been found that the behaviour of the potential distribution at the edge indicates a significant presence of positively charged states, with the charge density changing with the applied voltage. This work will predict, to a first approximation, the trend of the electric field at the edge of these devices after irradiation to high fluences. This prediction will provide key inputs in the development of edgeless radiation hard detectors.

  10. [Pneumothorax during right-sided nephrectomy in a heifer].

    Science.gov (United States)

    Nuss, K; Muggli, E; Gerspach, C; Schramm, S; Dettwiler, M; Bach, F; Ringer, S

    2016-01-01

    A 250-kg heifer had signs of colic attributable to urolithiasis of the right kidney. Medical treatment did not result in resolution of clinical signs, and nephrectomy was carried out. The surgery was started with the heifer standing, and the 13th rib was resected. However, during blunt dissection of the kidney, air suddenly entered the pleural space and the heifer had acute severe dyspnoea. The hole in the pleural cavity was sutured and a chest drain was placed. Inhalation anaesthesia was then induced and nephrectomy could be completed without further complications. The heifer was discharged 11 days postoperatively, and was healthy and had been integrated into the herd 12 months after surgery. Pneumothorax must be considered a possible complication of rib resection in right-sided nephrectomy in cattle.

  11. Optimization studies of the ITER low field side reflectometer.

    Science.gov (United States)

    Diem, S J; Wilgen, J B; Bigelow, T S; Hanson, G R; Harvey, R W; Smirnov, A P

    2010-10-01

    Microwave reflectometry will be used on ITER to measure the electron density profile, density fluctuations due to MHD/turbulence, edge localized mode (ELM) density transients, and as an L-H transition monitor. The ITER low field side reflectometer system will measure both core and edge quantities using multiple antenna arrays spanning frequency ranges of 15-155 GHz for the O-mode system and 55-220 GHz for the X-mode system. Optimization studies using the GENRAY ray-tracing code have been done for edge and core measurements. The reflectometer launchers will utilize the HE11 mode launched from circular corrugated waveguide. The launched beams are assumed to be Gaussian with a beam waist diameter of 0.643 times the waveguide diameter. Optimum launcher size and placement are investigated by computing the antenna coupling between launchers, assuming the launched and received beams have a Gaussian beam pattern.

  12. Neutrophils in Cancer: Two Sides of the Same Coin

    Directory of Open Access Journals (Sweden)

    Eileen Uribe-Querol

    2015-01-01

    Full Text Available Neutrophils are the most abundant leukocytes in blood and are considered to be the first line of defense during inflammation and infections. In addition, neutrophils are also found infiltrating many types of tumors. Tumor-associated neutrophils (TANs have relevant roles in malignant disease. Indeed neutrophils may be potent antitumor effector cells. However, increasing clinical evidence shows TANs correlate with poor prognosis. The tumor microenvironment controls neutrophil recruitment and in turn TANs help tumor progression. Hence, TANs can be beneficial or detrimental to the host. It is the purpose of this review to highlight these two sides of the neutrophil coin in cancer and to describe recent studies that provide some light on the mechanisms for neutrophil recruitment to the tumor, for neutrophils supporting tumor progression, and for neutrophil activation to enhance their antitumor functions.

  13. Light scattering of thin azobenzene side-chain polyester layers

    DEFF Research Database (Denmark)

    Kerekes, Á.; Lörincz, E.; Ramanujam, P.S.;

    2002-01-01

    Light scattering properties of liquid crystalline and amorphous azobenzene side-chain polyester layers used for optical data storage were examined by means of transmissive scatterometry. Comparative experiments show that the amorphous polyester has significantly lower light scattering...... characteristics than the liquid crystalline polyester. The amorphous samples have negligible polarization part orthogonal to the incident beam. the liquid crystalline samples have relative high orthogonal polarization part in light scattering, The light scattering results can be used to give a lower limit...... for the domain size in thin liquid crystalline polyester layers being responsible for the dominant light scattering. The characteristic domain Sizes obtained from the Fourier transformation of polarization microscopic Pictures confirm these values....

  14. Side-effects of improving CERN's spam filter

    CERN Multimedia

    2004-01-01

    To further improve the fight against spam (unsolicited email), CERN implemented in June a mechanism that returns electronic mail messages to the sender if the originating server is wrongly configured. This "reverse DNS lookup" is an increasingly widespread technique to identify whether the sending e-mail server is legitimate and has a valid host name. This change has nearly doubled the spam rejection efficiency at CERN. However, it has a known side-effect. A small number of correspondents are sending legitimate electronic mail to CERN from mail servers that are incorrectly configured (in technical terms, they do not have a reverse DNS registration). These persons will have their messages returned to them with an error message, provided their sender address is valid. The typical error message that the correspondent receives in such cases is "Relaying denied. No reverse DNS configured for IP". If a correspondent complains to you that emails they are sending you at CERN are being returned with...

  15. Growing Carbon Nanotubes from Both Sides of Graphene.

    Science.gov (United States)

    Jiang, Jinlong; Li, Yilun; Gao, Caitian; Kim, Nam Dong; Fan, Xiujun; Wang, Gunuk; Peng, Zhiwei; Hauge, Robert H; Tour, James M

    2016-03-23

    The design and synthesis of hybrid structures between graphene and carbon nanotubes is an intriguing topic in the field of carbon nanomaterials. Here the synthesis of vertically aligned CNT carpets underneath graphene and from both sides of graphene is described with continuous ordering over a large area. Scanning electron microscopy and Raman spectroscopic characterizations show that CNT carpets grow underneath graphene through a base-growth mechanism, and grow on top of graphene through a tip-growth mechanism. Good electrical contact is observed from the top CNT carpets, through the graphene layer, to the bottom CNT carpets. This sandwich-like CNT/graphene/CNT hybrid structure could provide an approach to design and fabricate multilayered graphene/CNTs materials, as well as potential applications in the fields of nanomanufacturing and energy storage.

  16. Modeling Supermarket Refrigeration Systems for Demand-Side Management

    Directory of Open Access Journals (Sweden)

    Jakob Stoustrup

    2013-02-01

    Full Text Available Modeling of supermarket refrigeration systems for supervisory control in the smart grid is presented in this paper. A modular modeling approach is proposed in which each module is modeled and identified separately. The focus of the work is on estimating the power consumption of the system while estimating the cold reservoir temperatures as well. The models developed for each module as well as for the overall integrated system are validated by real data collected from a supermarket in Denmark. The results show that the model is able to estimate the actual electrical power consumption with a high fidelity. Moreover a simulation benchmark is introduced based on the produced model for demand-side management in smart grid. Finally, a potential application of the proposed benchmark in direct control of the power/energy consumption is presented by a simple simulation example.

  17. An unexpected side-effect of a commonly used drug.

    Science.gov (United States)

    Fernández González, Francisco; Miranda, Samayra; Santiago Casiano, Mónica; Nieves, José; Adorno, Edgardo; Fernández González, Ricardo

    2013-01-01

    We report a case of a 68 year-old-female patient with clinical features of drug-induced lupus erythematosus after five years of treatment with amiodarone. She presented generalized skin rash, arthralgia on upper and lower extremities, associated with difficulty to walk. Remarkable laboratory results revealed a positive antinuclear antibody test and a skin rash biopsy showing a superficial and deep perivascular infiltrate of lymphocytes, histiocytes, and eosinophils. Once the etiology of the patient's symptoms was identified, the culprit drug was removed and she had a complete remission of all signs and symptoms. Early diagnose should be recognized for prompt intervention and avoid further complications associated with this rare side-effect.

  18. Psychiatric side effects of mefloquine: applications to forensic psychiatry.

    Science.gov (United States)

    Ritchie, Elspeth Cameron; Block, Jerald; Nevin, Remington Lee

    2013-01-01

    Mefloquine (previously marketed in the United States as Lariam®) is an antimalarial medication with potent psychotropic potential. Severe psychiatric side effects due to mefloquine intoxication are well documented, including anxiety, panic attacks, paranoia, persecutory delusions, dissociative psychosis, and anterograde amnesia. Exposure to the drug has been associated with acts of violence and suicide. In this article, we discuss the history of mefloquine use and describe plausible mechanisms of its psychotropic action. Mefloquine intoxication has not yet been successfully advanced in legal proceedings as a defense or as a mitigating factor, but it appears likely that it eventually will be. Considerations for the application of claims of mefloquine intoxication in forensic settings are discussed.

  19. Critical Questions About Left-Sided Infective Endocarditis.

    Science.gov (United States)

    San Román, J Alberto; Vilacosta, Isidre; López, Javier; Sarriá, Cristina

    2015-09-01

    Research in different topics in cardiovascular medicine is evolving rapidly. However, this is not the case for endocarditis, despite its being the cardiovascular disease with the highest mortality and, at the same time, the entity with relatively less scientific evidence supporting its treatment. Many problems are delaying research: it is an uncommon disease, few multicenter registries are ongoing, financing for research in this topic is lacking, randomization is costly, difficult, and considered unethical by some, and conclusions coming from propensity score analysis are taken as if they came from randomized trials. In this review, we put forward the main issues in need of evidence and propose a different approach to advance the understanding of left-sided infective endocarditis. We summarize the limited evidence available, the questions that are pending, and how we should proceed to answer them.

  20. Discussion on the Extensions of Meta-sided Exchange Rings%Meta-sided Exchange环的性质及扩张

    Institute of Scientific and Technical Information of China (English)

    唐再良; 张清

    2008-01-01

    陈焕艮对exchange环做了推广,提出了meta-sided exchange环的概念.本文在概念的基础上,利用exchange环的性质,研究meta-sided exchange环的一些重要性质及其扩张,得到一些与exchange环类似的结论,同时发现meta-sided exchange并没有上述exchange环的对称结构,并对meta-sided exchange环进行了比深入的刻画.

  1. Radiotherapy and "new" drugs-new side effects?

    Directory of Open Access Journals (Sweden)

    Niyazi Maximilian

    2011-12-01

    Full Text Available Abstract Background and purpose Targeted drugs have augmented the cancer treatment armamentarium. Based on the molecular specificity, it was initially believed that these drugs had significantly less side effects. However, currently it is accepted that all of these agents have their specific side effects. Based on the given multimodal approach, special emphasis has to be placed on putative interactions of conventional cytostatic drugs, targeted agents and other modalities. The interaction of targeted drugs with radiation harbours special risks, since the awareness for interactions and even synergistic toxicities is lacking. At present, only limited is data available regarding combinations of targeted drugs and radiotherapy. This review gives an overview on the current knowledge on such combined treatments. Materials and methods Using the following MESH headings and combinations of these terms pubmed database was searched: Radiotherapy AND cetuximab/trastuzumab/panitumumab/nimotuzumab, bevacizumab, sunitinib/sorafenib/lapatinib/gefitinib/erlotinib/sirolimus, thalidomide/lenalidomide as well as erythropoietin. For citation crosscheck the ISI web of science database was used employing the same search terms. Results Several classes of targeted substances may be distinguished: Small molecules including kinase inhibitors and specific inhibitors, antibodies, and anti-angiogenic agents. Combination of these agents with radiotherapy may lead to specific toxicities or negatively influence the efficacy of RT. Though there is only little information on the interaction of molecular targeted radiation and radiotherapy in clinical settings, several critical incidents are reported. Conclusions The addition of molecular targeted drugs to conventional radiotherapy outside of approved regimens or clinical trials warrants a careful consideration especially when used in conjunction in hypo-fractionated regimens. Clinical trials are urgently needed in order to

  2. Side 2: MSM positioning of STIS CCD Modes

    Science.gov (United States)

    Sahu, Kailash

    2000-07-01

    The MSM positions for different STIS modes are slightly different when the STIS is run through side 2 than when it is run from side 1. These MSM positions for various STIS prime CCD modes shall be confirmed by taking images with the IM Pt/Cr/Ne calibration lamp. For first order long-slit modes, the exposures shall be made through 52x0.1arcsec slit. For the echelle modes, the exposures shall be made through echelle slits of the nominal height, to avoid order confusion. One exposure shall be taken for each prime mode except for the medium dispersion{M}, long slit modes. For the medium dispersion, long-slit modes, additional exposures shall be taken at the long and short wavelength settings of the nominal scan range. Exposures shall be sufficiently long to bring out enough line features to confirm wavelength identifications, with sufficient signal to noise to reveal the shadows of the fiducials in the long slit images to confirm spatial pointing. This activity will test all primary modes and test the extremes of the MSM scanning cylinders by observing the extreme settings of the modes. RESULTS: All images will be downlinked and analyzed. The results are confirmation of the standard MSM encoder values for each mode. If the wavelength shifts are less than the budgeted value, the changes will be handled through updating the siaf files. If excess shifts are seen, new MSM positions will be derived and uplinked to the onboard MSM pointing table. Any modes for which revised MSM positions are uplinked will have to be re-observed for confirmation that the correct offsets were applied.

  3. Side 2: MSM Positioning of STIS MAMA Modes

    Science.gov (United States)

    Sahu, Kailash

    2000-07-01

    The MSM positions for different STIS modes are slightly different when the STIS is run through side 2 than when it is run from side 1. These MSM positions for various STIS prime MAMA modes shall be confirmed by taking images with the IM Pt/Cr/Ne calibration lamp. For first order long-slit modes, the exposures shall be made through 52x0.1arcsec slit. For the echelle modes, the exposures shall be made through echelle slits of the nominal height, to avoid order confusion. One exposure shall be taken for each prime mode except for the medium dispersion{M}, long slit modes. For the medium dispersion, long-slit modes, additional exposures shall be taken at the long and short wavelength settings of the nominal scan range. Exposures shall be sufficiently long to bring out enough line features to confirm wavelength identifications, with sufficient signal to noise to reveal the shadows of the fiducials in the long slit images to confirm spatial pointing. This activity will test all primary modes and test the extremes of the MSM scanning cylinders by observing the extreme settings of the modes. RESULTS: All images will be downlinked and analyzed. The results are confirmation of the standard MSM encoder values for each mode. If the wavelength shifts are less than the budgeted value, the changes will be handled through updating the siaf files. If excess shifts are seen, new MSM positions will be derived and uplinked to the onboard MSM pointing table. Any modes for which revised MSM positions are uplinked will have to be re-observed for confirmation that the correct offsets were applied.

  4. Interactive client side data visualization with d3.js

    Science.gov (United States)

    Rodzianko, A.; Versteeg, R.; Johnson, D. V.; Soltanian, M. R.; Versteeg, O. J.; Girouard, M.

    2015-12-01

    Geoscience data associated with near surface research and operational sites is increasingly voluminous and heterogeneous (both in terms of providers and data types - e.g. geochemical, hydrological, geophysical, modeling data, of varying spatiotemporal characteristics). Such data allows scientists to investigate fundamental hydrological and geochemical processes relevant to agriculture, water resources and climate change. For scientists to easily share, model and interpret such data requires novel tools with capabilities for interactive data visualization. Under sponsorship of the US Department of Energy, Subsurface Insights is developing the Predictive Assimilative Framework (PAF): a cloud based subsurface monitoring platform which can manage, process and visualize large heterogeneous datasets. Over the last year we transitioned our visualization method from a server side approach (in which images and animations were generated using Jfreechart and Visit) to a client side one that utilizes the D3 Javascript library. Datasets are retrieved using web service calls to the server, returned as JSON objects and visualized within the browser. Users can interactively explore primary and secondary datasets from various field locations. Our current capabilities include interactive data contouring and heterogeneous time series data visualization. While this approach is very powerful and not necessarily unique, special attention needs to be paid to latency and responsiveness issues as well as to issues as cross browser code compatibility so that users have an identical, fluid and frustration-free experience across different computational platforms. We gratefully acknowledge support from the US Department of Energy under SBIR Award DOE DE-SC0009732, the use of data from the Lawrence Berkeley National Laboratory (LBNL) Sustainable Systems SFA Rifle field site and collaboration with LBNL SFA scientists.

  5. Intelligent demand side management of residential building energy systems

    Science.gov (United States)

    Sinha, Maruti N.

    Advent of modern sensing technologies, data processing capabilities and rising cost of energy are driving the implementation of intelligent systems in buildings and houses which constitute 41% of total energy consumption. The primary motivation has been to provide a framework for demand-side management and to improve overall reliability. The entire formulation is to be implemented on NILM (Non-Intrusive Load Monitoring System), a smart meter. This is going to play a vital role in the future of demand side management. Utilities have started deploying smart meters throughout the world which will essentially help to establish communication between utility and consumers. This research is focused on investigation of a suitable thermal model of residential house, building up control system and developing diagnostic and energy usage forecast tool. The present work has considered measurement based approach to pursue. Identification of building thermal parameters is the very first step towards developing performance measurement and controls. The proposed identification technique is PEM (Prediction Error Method) based, discrete state-space model. The two different models have been devised. First model is focused toward energy usage forecast and diagnostics. Here one of the novel idea has been investigated which takes integral of thermal capacity to identify thermal model of house. The purpose of second identification is to build up a model for control strategy. The controller should be able to take into account the weather forecast information, deal with the operating point constraints and at the same time minimize the energy consumption. To design an optimal controller, MPC (Model Predictive Control) scheme has been implemented instead of present thermostatic/hysteretic control. This is a receding horizon approach. Capability of the proposed schemes has also been investigated.

  6. Wear and Thermal Stress Analysis of Side Dam for Twin Roll Strip Casting

    Institute of Scientific and Technical Information of China (English)

    LI Chao-feng; DI Hong-shuang; ZHANG Xiao-ming; WANG Guo-dong; LIU Xiang-hua

    2004-01-01

    The side dam technology for twin roll strip casting was discussed. The effect of pre-heating temperature, material and design of side dam on the process stability and surface quality of products was analyzed. The wear and erosion of side dam for different steel grades were described. Two types of side dam designs, namely integral type and combined type, were used in the experiment, and the suitable position of side dam was determined by experiment. The results show that the combined side dam is better than the integral one in process stability and long service life. The temperature fields and thermal stress fields in side dam during strip casting were analyzed using the finite element analysis software, and the causes of side dam cracking were explained.

  7. Managing Radiation Therapy Side Effects: What to Do When You Have Loose Stools (Diarrhea)

    Science.gov (United States)

    ... rice • White toast Fruits and other foods • Applesauce • Bananas • Canned fruit, such as peaches and pears • Gelatin ( ... series of 9 Radiation Therapy Side Effects Fact Sheets at: www. cancer. gov/ radiation- side- effects

  8. Augmentation of partially regenerated nerves by end-to-side side-to-side grafting neurotization: experience based on eight late obstetric brachial plexus cases

    Directory of Open Access Journals (Sweden)

    Moharram Ashraf N

    2006-12-01

    Full Text Available Abstract Objective The effect of end-to-side neurotization of partially regenerated recipient nerves on improving motor power in late obstetric brachial plexus lesions, so-called nerve augmentation, was investigated. Methods Eight cases aged 3 – 7 years were operated upon and followed up for 4 years (C5,6 rupture C7,8T1 avulsion: 5; C5,6,7,8 rupture T1 avulsion:1; C5,6,8T1 rupture C7 avulsion:1; C5,6,7 ruptureC8 T1 compression: one 3 year presentation after former neurotization at 3 months. Grade 1–3 muscles were neurotized. Grade0 muscles were neurotized, if the electromyogram showed scattered motor unit action potentials on voluntary contraction without interference pattern. Donor nerves included: the phrenic, accessory, descending and ascending loops of the ansa cervicalis, 3rd and 4th intercostals and contralateral C7. Results Superior proximal to distal regeneration was observed firstly. Differential regeneration of muscles supplied by the same nerve was observed secondly (superior supraspinatus to infraspinatus regeneration. Differential regeneration of antagonistic muscles was observed thirdly (superior biceps to triceps and pronator teres to supinator recovery. Differential regeneration of fibres within the same muscle was observed fourthly (superior anterior and middle to posterior deltoid regeneration. Differential regeneration of muscles having different preoperative motor powers was noted fifthly; improvement to Grade 3 or more occurred more in Grade2 than in Grade0 or Grade1 muscles. Improvements of cocontractions and of shoulder, forearm and wrist deformities were noted sixthly. The shoulder, elbow and hand scores improved in 4 cases. Limitations The sample size is small. Controls are necessary to rule out any natural improvement of the lesion. There is intra- and interobserver variability in testing muscle power and cocontractions. Conclusion Nerve augmentation improves cocontractions and muscle power in the biceps, pectoral

  9. The effect of irradiating adaxial or abaxial side on photosynthesis of rose leaves

    OpenAIRE

    Paradiso, R.; Marcelis, L. F. M.

    2012-01-01

    Abstract: In many cropping systems most of the light irradiates the adaxial side of leaves. However, in cropping systems with intra canopy lighting a reasonable fraction of light may irradiate even the abaxial side of the leaves. The aim of this study was to investigate the effect of irradiating the abaxial leaf side compared to irradiating the adaxial side, in rose plants grown in glasshouse with the bending technique. The instantaneous effects on the optical properties and the light respons...

  10. Application of Healthy-Side Needling to Treatment of Apoplectic Hemiplegia

    Institute of Scientific and Technical Information of China (English)

    范刚启; 吴旭; 薛忠元

    2002-01-01

    @@ Acupuncture is effective for the treatment of apoplectic hemiplegia, and the acupoint on the paralytic side is often selected for acupuncture. However, some doctor prefers healthy-side needling with quite satisfactory results. We study and review the treatment of apoplexy by healthy-side needling to further improve its therapeutic effects.

  11. [Internal medicine and local anesthesia in dentistry. A review of possible side effects].

    Science.gov (United States)

    Fennis, J F

    1996-05-01

    When using local anaesthesia the dentist may be confronted with a variety of side effects, either caused by the anaesthetic solution itself or its additives, including vasoconstrictive drugs such as epinephrine. Early recognition and treatment of these side-effects are essential. Even more important is the possible prevention of such side-effects by a properly taken medical history before using local anaesthesia.

  12. 14 CFR 25.363 - Side load on engine and auxiliary power unit mounts.

    Science.gov (United States)

    2010-01-01

    ... § 25.363 Side load on engine and auxiliary power unit mounts. (a) Each engine and auxiliary power unit... the side load on the engine and auxiliary power unit mount, at least equal to the maximum load factor... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Side load on engine and auxiliary...

  13. Mechanisms of sound amplification and sound reduction in the flapping flight of side-by-side airfoils

    Science.gov (United States)

    Manela, A.; Halachmi, M.

    2015-06-01

    The acoustic signature of side-by-side airfoils, subject to small-amplitude harmonic pitching and incoming flow unsteadiness, is investigated. The two-dimensional near-field problem is formulated using thin-airfoil theory, where flow unsteadiness is modeled as a passing line vortex, and wake evolution is calculated via the Brown and Michael formula. Assuming that the setup is acoustically compact, acoustic radiation is obtained by means of the Powell-Howe acoustic analogy. The associated compact Green's function is calculated numerically using potential-flow analysis of the fluid-structure flow domain. Results, comparing the acoustic radiation of the double-airfoil system to a reference case of a single airfoil, point to several mechanisms of sound attenuation and sound amplification, caused by airfoil-airfoil and airfoils-wake interactions. It is found that counter-phase pitching of the airfoils results in effective cloaking of the system, which otherwise becomes significantly noisy (as a 5/2-power of the pitching frequency) at large frequencies. In addition, depending on the distance between airfoils, in-phase pitching may result in an acoustic signature equivalent to a single airfoil (when the airfoils are adjacent) or to two separate airfoils (when the airfoils are far apart). In general, flow unsteadiness produces more sound when interacting with a double (compared with a single) airfoil setup. However, airfoils' nonlinear wake-wake interactions give rise to a sound reduction mechanism, which becomes most efficient at times when incoming vorticity passes above airfoils' leading and trailing edges. The present scheme can be readily extended to consider the acoustic properties of various double-airfoil configurations, as well as multiple (> 2) airfoil setups.

  14. Addressing reverse osmosis fouling within water reclamation--a side-by-side comparison of low-pressure membrane pretreatments.

    Science.gov (United States)

    Kent, Fraser C; Farahbakhsh, Khosrow

    2011-06-01

    A tertiary membrane filtration (TMF) pilot operating on secondary effluent and a membrane bioreactor (MBR) were setup in a side-by-side study as pretreatments for two identical reverse osmosis pilot systems. The water quality of the permeate from both low-pressure membrane pretreatment systems and the fouling rate of the reverse osmosis systems were compared to assess the capabilities of the two low-pressure membrane pretreatments to prevent organic fouling of the reverse osmosis systems. Both pretreatment pilots were setup using typical operating conditions (i.e., solids retention time and mixed-liquor suspended solids). A consistent difference in water quality and reverse osmosis performance was demonstrated during the 12-month study. The MBR permeate consistently had significantly lower total organic carbon (TOC) and chemical oxygen demand concentrations, but higher color and specific UV absorbance compared with the permeate from the TMF pretreatment. The pretreatment with the MBR gave an average reverse osmosis fouling rate over the entire study (0.27 Lmh/bar.month) that was less than half of the value found for the reverse osmosis with TMF pretreatment (0.60 Lmh/bar.month). A correlation of reverse osmosis feed TOC concentration with average reverse osmosis fouling rate also was established, independent of the pretreatment method used. Results from a cleaning analysis, energy dispersive spectroscopy, and fourier transformed infrared reflectometry confirmed that the foulants were primarily organic in nature. It is concluded that, for this type of application and setup, MBR systems present an advantage over tertiary membrane polishing of secondary effluent for reverse osmosis pretreatment.

  15. Managing a live music performance: A supply-side analysis

    Directory of Open Access Journals (Sweden)

    Bianca Manners

    2015-02-01

    Full Text Available Purpose and objective: The purpose of this research is to determine what managers regard as important critical success factors in ensuring a memorable visitor experience at a live music performance.Problem investigated: When organising a live music performance, it is evident that the various characteristics that form part of the visitor experience have to be considered. The critical success factors of live music performances from the supply side are fundamental, since the costs of organising live music performances are high, the needs of the visitors are constantly changing and competition plays a major role in the success of such events. Management furthermore constantly needs to be aware of the ever-changing external environment by determining what factors visitors consider to be vital for a rewarding experience at a major music event. This is extremely important since the concept of experience has become more pervasive, mainly given that the event sector, such as live music performances, has adopted experience as a tool to make individual businesses more competitive, as the organisations operating within this sector exist to provide consumers with an experience.Design and/or methodology and/or approach: A qualitative research method, by means of interviews, was used to obtain the relevant information from the selected participants. All the data collected in the process were transcribed into text and presented in narrative form. The six steps of data analysis and interpretation were applied to analyse the data.Findings and impications: The following four major themes emerged from the analysis; each theme was differentiated in terms of various categories and subcategories. Theme 1:The most important aspects for a memorable visitor experience; Theme 2:Main purpose when organising a live music performance; Theme 3:Important aspects regarding the management of a live music performance; Theme 4:Timing of event management. Based

  16. Validity and reliability of 6-a-side small-sided game locomotor performance in assessing physical fitness in football players

    NARCIS (Netherlands)

    Stevens, T.G.A.; Ruiter, de C.J.; Beek, P.J.; Savelsbergh, G.J.P.

    2016-01-01

    ABSTRACTIn order to determine whether small-sided game (SSG) locomotor performance can serve as a fitness indicator, we (1) compared 6-a-side (6v6) SSG-intensity of players varying in fitness and skill, (2) examined the relationship of the 6v6-SSG and Yo-Yo IR2 and (3) and assessed the reliability o

  17. What Motivates Lay Third Parties to Take Sides in a Conflict? Examining the Relationships between the Big Five Personality Traits and Side-taking Motives

    NARCIS (Netherlands)

    Yang, Huadong; Li, Chaoping; Wang, Qing; Hendriks, A. A. Jolijn

    2011-01-01

    Taking sides is one of the reactions available to third parties in handling a dispute. From the perspective of individual differences, this study was aimed at identifying lay third parties' motives for side taking and exploring their relations with the Big Five personality traits. We tested our assu

  18. An Examination of Psychotropic Medication Side Effects: Does Taking a Greater Number of Psychotropic Medications from Different Classes Affect Presentation of Side Effects in adults with ID?

    Science.gov (United States)

    Mahan, Sara; Holloway, Jodie; Bamburg, Jay W.; Hess, Julie A.; Fodstad, Jill C.; Matson, Johnny L.

    2010-01-01

    This study examined whether the number of psychotropic medications an individual is taking across classes influences side effects among adults with Intellectual Disability (ID). Participants were 80 adults diagnosed with ID. Dependent variables were the composite score and domain scores of the "Matson Evaluation of Drug Side-Effects" ("MEDS"),…

  19. Review of the side-effect profile of buspirone.

    Science.gov (United States)

    Newton, R E; Marunycz, J D; Alderdice, M T; Napoliello, M J

    1986-03-31

    In 984 patients with generalized anxiety disorder who received buspirone in double-blind studies, the incidence of drowsiness (9 percent) did not differ significantly from that (10 percent) reported in 334 patients who received placebo. A probability value of p less than or equal to 0.10 was the criterion for significance. The incidence of drowsiness in buspirone-treated patients was significantly less than that in each of the groups receiving diazepam (32 percent), clorazepate (26 percent), lorazepam (58 percent), or alprazolam (43 percent). The side effects that did occur significantly more frequently in the buspirone group than in the placebo group were dizziness (9 percent versus 2 percent), headache (7 percent versus 2 percent), nervousness (4 percent versus 1 percent), light-headedness (4 percent versus less than 1 percent), diarrhea (3 percent versus less than 1 percent), paresthesia (2 percent versus less than 1 percent), excitation (2 percent versus less than 1 percent), and sweating/clamminess (1 percent versus 0 percent). The severities of these effects were predominantly rated as only mild or moderate. Fatigue occurred less frequently in buspirone-treated patients than in those receiving any of the benzodiazepines, and weakness occurred more frequently in diazepam-treated patients. Depression occurred less frequently in buspirone-treated patients than in those receiving clorazepate, diazepam, or lorazepam. Impotence occurred only in clorazepate- and lorazepam-treated patients. Decreased libido occurred more frequently in diazepam-treated patients, whereas increased libido was more frequent in clorazepate-treated patients. Nausea was reported more frequently in buspirone-treated patients than in those receiving clorazepate, diazepam, or alprazolam; diarrhea occurred more frequently in the buspirone group than in the diazepam group. The mean daily doses of the various treatments were buspirone, 20 mg; diazepam, 20 mg; clorazepate, 24 mg; lorazepam, 3 mg

  20. Evaluation of Side Stream Filtration Technology at Oak Ridge National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Boyd, Brian K.

    2014-08-01

    This technology evaluation was performed by Pacific Northwest National Laboratory and Oak Ridge National Laboratory on behalf of the Federal Energy Management Program. The objective was to quantify the benefits side stream filtration provides to a cooling tower system. The evaluation assessed the performance of an existing side stream filtration system at a cooling tower system at Oak Ridge National Laboratory’s Spallation Neutron Source research facility. This location was selected because it offered the opportunity for a side-by-side comparison of a system featuring side stream filtration and an unfiltered system.

  1. Side-to-side range of movement variability in variants of the median and radial neurodynamic test sequences in asymptomatic people.

    Science.gov (United States)

    Stalioraitis, Vaidas; Robinson, Kim; Hall, Toby

    2014-08-01

    Side-to-side discrepancy in range of motion (ROM) during upper limb neurodynamic testing is used in part to identify abnormal peripheral nerve mechanosensitivity and is one of three factors to consider in determining a positive test. Large side-to-side variability is reported for some variants of the upper limb neurodynamic test sequences, however discrepancies for other test variants are unknown. Hence the purpose of this study was to evaluate side-to-side discrepancy in elbow flexion ROM during two variants of upper limb neurodynamic test sequence for the median and radial nerves. 51 asymptomatic subjects (26 females, mean age 29.69 years) were evaluated. A uniaxial electrogoniometer was used to measure elbow flexion ROM at onset of resistance (R1) and onset of discomfort (P1) during the median and radial neurodynamic tests on each side. Reliability was determined by testing 20 subjects twice and was found to be good (ICC greater than 0.88 and SEM less than 4.02°). There was no significant difference in mean ROM between sides. Lower-bound scores indicate that intra-individual, inter-limb differences of more than 15° for the median nerve and 11° for the radial nerve exceeds the range of normal ROM asymmetry on neurodynamic testing at R1 and P1. Correlation of ROM between limbs was significant with R(2) values of 0.62 and 0.85 for the median and radial nerves respectively. These finding provide clinicians with information regarding normal side-to-side variability in ROM during two commonly used variants of neurodynamic tests.

  2. Track Detection in Railway Sidings Based on MEMS Gyroscope Sensors

    Directory of Open Access Journals (Sweden)

    Miguel A. López

    2012-11-01

    Full Text Available The paper presents a two-step technique for real-time track detection in single-track railway sidings using low-cost MEMS gyroscopes. The objective is to reliably know the path the train has taken in a switch, diverted or main road, immediately after the train head leaves the switch. The signal delivered by the gyroscope is first processed by an adaptive low-pass filter that rejects noise and converts the temporal turn rate data in degree/second units into spatial turn rate data in degree/meter. The conversion is based on the travelled distance taken from odometer data. The filter is implemented to achieve a speed-dependent cut-off frequency to maximize the signal-to-noise ratio. Although direct comparison of the filtered turn rate signal with a predetermined threshold is possible, the paper shows that better detection performance can be achieved by processing the turn rate signal with a filter matched to the rail switch curvature parameters. Implementation aspects of the track detector have been optimized for real-time operation. The detector has been tested with both simulated data and real data acquired in railway campaigns.

  3. Track detection in railway sidings based on MEMS gyroscope sensors.

    Science.gov (United States)

    Broquetas, Antoni; Comerón, Adolf; Gelonch, Antoni; Fuertes, Josep M; Castro, J Antonio; Felip, Damià; López, Miguel A; Pulido, José A

    2012-11-23

    The paper presents a two-step technique for real-time track detection in single-track railway sidings using low-cost MEMS gyroscopes. The objective is to reliably know the path the train has taken in a switch, diverted or main road, immediately after the train head leaves the switch. The signal delivered by the gyroscope is first processed by an adaptive low-pass filter that rejects noise and converts the temporal turn rate data in degree/second units into spatial turn rate data in degree/meter. The conversion is based on the travelled distance taken from odometer data. The filter is implemented to achieve a speed-dependent cut-off frequency to maximize the signal-to-noise ratio. Although direct comparison of the filtered turn rate signal with a predetermined threshold is possible, the paper shows that better detection performance can be achieved by processing the turn rate signal with a filter matched to the rail switch curvature parameters. Implementation aspects of the track detector have been optimized for real-time operation. The detector has been tested with both simulated data and real data acquired in railway campaigns.

  4. RETRACTED: Flap side edge noise modeling and prediction

    Science.gov (United States)

    Guo, Yueping

    2013-08-01

    This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy).This article has been retracted at the request of the first author because of the overlap with previously published papers. The first author takes full responsibility and sincerely apologizes for the error made.This article has been retracted at the request of the Editor-in-Chief.The article duplicates significant parts of an earlier paper by the same author, published in AIAA (Y.P. Guo, Aircraft flap side edge noise modeling and prediction. American Institute of Aeronautics and Astronautics, (2011), 10.2514/6.2011-2731). Prior to republication, conference papers should be comprehensively extended, and re-use of any data should be appropriately cited. As such this article represents a severe abuse of the scientific publishing system. The scientific community takes a very strong view on this matter and apologies are offered to readers of the journal that this was not detected during the submission process.

  5. Recent progress in single sided gamma-ray tomography

    Energy Technology Data Exchange (ETDEWEB)

    Thoe, R.S.

    1994-04-01

    The use of scattered radiation for radiography has many potential advantages over conventional projection techniques: For high energy photons the scattering process strongly dominates all other processes. The intensity of scattered radiation is due directly to the electron density and highly insensitive to chemical composition. Finally, the use of scattered radiation allows the investigator to position the radiation source-on-the same side of the object as the detector. In this paper I will present some recent results of a set of measurements made with our uncollimated Compton backscattering tomography apparatus. This technique uses the Compton energy shift of scattered gamma rays to determine the scattering site. By measuring the spectrum of these scattered gamma rays it is then possible to determine the electron density of the object being investigated. I will give a brief description of the apparatus and present the results of numerous measurements made on a brass phantom with voids placed at various depths. These results imply that for this crude apparatus occlusions as small as one cubic millimeter may be located to an accuracy of about one millimeter at depths of about 15 millimeters in solid brass.

  6. Fat tissues, the brite and the dark sides.

    Science.gov (United States)

    Chen, Yong; Pan, Ruping; Pfeifer, Alexander

    2016-11-01

    Fat tissue is well known for its capacity to store energy and its detrimental role in obesity and metaflammation. However, humans possess different types of fat that have different functions in physiology and metabolic diseases. Apart from white adipose tissue (WAT), the body's main energy storage, there is also brown adipose tissue (BAT) that dissipates energy as a defense against cold and maintains energy balance for the whole body. BAT is present not only in newborns but also in adult humans and its mass correlates with leanness. Moreover, "brown-like" adipocytes have been detected in human WAT. These "brown-in-white" (brite) or beige cells can be induced by cold and a broad spectrum of pharmacological substances and, therefore, they are also known as "inducible brown adipocytes." Activation of brown and/or brite adipocytes reduces metabolic diseases, at least in murine models of obesity. Thus, brown/brite adipocytes represent the "brite" side of fat and are potential targets for novel therapeutic approaches for treatment of obesity and obesity-associated diseases.

  7. Corticosteroid-related central nervous system side effects

    Directory of Open Access Journals (Sweden)

    Miriam Ciriaco

    2013-01-01

    Full Text Available Corticosteroids have been used since the 50s as anti-inflammatory and immunosuppressive drugs for the treatment of several pathologies such as asthma, allergy, rheumatoid arthritis, and dermatological disorders. Corticosteroids have three principal mechanisms of action: 1 inhibit the synthesis of inflammatory proteins blocking NF-kB, 2 induce the expression of anti-inflammatory proteins by IkB and MAPK phosphatase I, and 3 inhibit 5-lipoxygenase and cyclooxygenase-2. The efficacy of glucocorticoids in alleviating inflammatory disorders results from the pleiotropic effects of the glucocorticoid receptors on multiple signaling pathways. However, they have adverse effects: Growth retardation in children, immunosuppression, hypertension, hyperglycemia, inhibition of wound repair, osteoporosis, metabolic disturbances, glaucoma, and cataracts. Less is known about psychiatric or side effects on central nervous system, as catatonia, decreased concentration, agitation, insomnia, and abnormal behaviors, which are also often underestimated in clinical practice. The aim of this review is to highlight the correlation between the administration of corticosteroids and CNS adverse effects, giving a useful guide for prescribers including a more careful assessment of risk factors and encourage the use of safer doses of this class of drugs.

  8. Client-Side Event Processing for Personalized Web Advertisement

    Science.gov (United States)

    Stühmer, Roland; Anicic, Darko; Sen, Sinan; Ma, Jun; Schmidt, Kay-Uwe; Stojanovic, Nenad

    The market for Web advertisement is continuously growing and correspondingly, the number of approaches that can be used for realizing Web advertisement are increasing. However, current approaches fail to generate very personalized ads for a current Web user that is visiting a particular Web content. They mainly try to develop a profile based on the content of that Web page or on a long-term user's profile, by not taking into account current user's preferences. We argue that by discovering a user's interest from his current Web behavior we can support the process of ad generation, especially the relevance of an ad for the user. In this paper we present the conceptual architecture and implementation of such an approach. The approach is based on the extraction of simple events from the user interaction with a Web page and their combination in order to discover the user's interests. We use semantic technologies in order to build such an interpretation out of many simple events. We present results from preliminary evaluation studies. The main contribution of the paper is a very efficient, semantic-based client-side architecture for generating and combining Web events. The architecture ensures the agility of the whole advertisement system, by complexly processing events on the client. In general, this work contributes to the realization of new, event-driven applications for the (Semantic) Web.

  9. Traditional Jewelry on Both Sides of the Danube River

    Directory of Open Access Journals (Sweden)

    P. Chaushev

    2015-09-01

    Full Text Available From the Ancient times Danube River acts as stabile and almost uncontested Northern border of Bulgarian lands. For a very long period it divides different populations speaking different languages, developing different cultures and political units. In the same times Danube River unites it is both banks by cheap and easy to manage transportation. More than this Danube as a liquid border connects populations from the both banks with Central Europe serving as a vehicle for people, goods, money and ideas. The aim of this article is to explore one particular segment of culture connections - the evolution of traditional jewelry from 19th to early 20th century in the region of Northern Bulgaria and Southern Romania. The focus is on snake or dragon motifs carved on belt buckles originated from both sides of the border. This and related believes and cult practices reveals close cultural and commercial ties crossing Danube River. During my research I came across material that showed that those motifs were found in several Balkan countries (Serbia and Greece. The decoration of this traditional jewelry is typical for the Orient, but it is common among the Christian population of the Balkan Peninsula. It shows that in those times the Danube River was acting mostly as natural, not as a political or cultural border.

  10. [Vascular calcifications, the hidden side effects of vitamin K antagonists].

    Science.gov (United States)

    Bennis, Youssef; Vengadessane, Subashini; Bodeau, Sandra; Gras, Valérie; Bricca, Giampiero; Kamel, Saïd; Liabeuf, Sophie

    2016-09-01

    Despite the availability of new oral anticoagulants, vitamin K antagonists (VKA, such as fluindione, acenocoumarol or warfarin) remain currently the goal standard medicines for oral prevention or treatment of thromboembolic disorders. They inhibit the cycle of the vitamin K and its participation in the enzymatic gamma-carboxylation of many proteins. The VKA prevent the activation of the vitamin K-dependent blood clotting factors limiting thus the initiation of the coagulation cascade. But other proteins are vitamin K-dependent and also remain inactive in the presence of VKA. This is the case of matrix Gla-protein (MGP), a protein that plays a major inhibitory role in the development of vascular calcifications. Several experimental and epidemiological results suggest that the use of the VKA could promote the development of vascular calcifications increasing thus the cardiovascular risk. This risk seems to be higher in patients with chronic kidney disease or mellitus diabetes who are more likely to develop vascular calcifications, and may be due to a decrease of the MGP activity. This review aims at summarizing the data currently available making vascular calcifications the probably underestimated side effects of VKA.

  11. Solving modified systems with multiple right-hand sides

    Energy Technology Data Exchange (ETDEWEB)

    Simoncini, V.; Gallopoulos, E. [Univ. of Patras (Greece)

    1996-12-31

    In this talk we discuss the iterative solution of large linear systems of the form (A + USV{sup H})X = B, where A is an n x n non-Hermitian matrix, USV{sup H} is a rank-r modification of A and B is of rank s with s, r {much_lt} n. We analyze several approaches that exploit the structure of the coefficient matrix so as to solve the systems more efficiently than if one were to apply a non-hermitian solver to the original systems. In the development of procedures, we take into account the presence of both the low-rank modification and the several right-hand sides. Interesting issues connected to this problem originate from the quest for techniques that accelerate the underlying iterative solvers: preconditioning (e.g. inner-outer iteration strategies), domain decomposition, and continuation methods. Experiments are provided to analyze the behavior of the methods depending on the structure of the rectangular matrices. Preconditioning strategies are explored for an efficient implementation on the transformed systems.

  12. Crossings as a side effect of dependency lengths

    CERN Document Server

    Ferrer-i-Cancho, Ramon

    2015-01-01

    The syntactic structure of sentences exhibits a striking regularity: dependencies tend to not cross when drawn above the sentence. Here we investigate two competing hypotheses for the origins of non-crossing dependencies. The traditional hypothesis is that the low frequency of dependency crossings arises from an independent principle of syntax that reduces crossings practically to zero. An alternative to this view is the hypothesis that crossings are a side effect of dependency lengths. According to this view, sentences with shorter dependency lengths should tend to have fewer crossings. We recast the traditional view as a null hypothesis where one of the variables, i.e. the number of crossings, is mean independent of the other, i.e. the sum of dependency lengths. The alternative view is then a positive correlation between these two variables. In spite of the rough estimation of dependency crossings that this sum provides, we are able to reject the traditional view in the majority of languages considered. The...

  13. Side effects of normalising radial basis function networks.

    Science.gov (United States)

    Shorten, R; Murray-Smith, R

    1996-05-01

    Normalisation of the basis function activations in a Radial Basis Function (RBF) network is a common way of achieving the partition of unity often desired for modelling applications. It results in the basis functions covering the whole of the input space to the same degree. However, normalisation of the basis functions can lead to other effects which are sometimes less desirable for modelling applications. This paper describes some side effects of normalisation which fundamentally alter properties of the basis functions, e.g. the shape is no longer uniform, maxima of basis functions can be shifted from their centres, and the basis functions are no longer guaranteed to decrease monotonically as distance from their centre increases--in many cases basis functions can 'reactivate', i.e. re-appear far from the basis function centre. This paper examines how these phenomena occur, discusses their relevance for non-linear function approximation and examines the effect of normalisation on the network condition number and weights.

  14. High-Resolution Underwater Mapping Using Side-Scan Sonar.

    Science.gov (United States)

    Burguera, Antoni; Oliver, Gabriel

    2016-01-01

    The goal of this study is to generate high-resolution sea floor maps using a Side-Scan Sonar(SSS). This is achieved by explicitly taking into account the SSS operation as follows. First, the raw sensor data is corrected by means of a physics-based SSS model. Second, the data is projected to the sea-floor. The errors involved in this projection are thoroughfully analysed. Third, a probabilistic SSS model is defined and used to estimate the probability of each sea-floor region to be observed. This probabilistic information is then used to weight the contribution of each SSS measurement to the map. Because of these models, arbitrary map resolutions can be achieved, even beyond the sensor resolution. Finally, a geometric map building method is presented and combined with the probabilistic approach. The resulting map is composed of two layers. The echo intensity layer holds the most likely echo intensities at each point in the sea-floor. The probabilistic layer contains information about how confident can the user or the higher control layers be about the echo intensity layer data. Experimental results have been conducted in a large subsea region.

  15. High-Resolution Underwater Mapping Using Side-Scan Sonar.

    Directory of Open Access Journals (Sweden)

    Antoni Burguera

    Full Text Available The goal of this study is to generate high-resolution sea floor maps using a Side-Scan Sonar(SSS. This is achieved by explicitly taking into account the SSS operation as follows. First, the raw sensor data is corrected by means of a physics-based SSS model. Second, the data is projected to the sea-floor. The errors involved in this projection are thoroughfully analysed. Third, a probabilistic SSS model is defined and used to estimate the probability of each sea-floor region to be observed. This probabilistic information is then used to weight the contribution of each SSS measurement to the map. Because of these models, arbitrary map resolutions can be achieved, even beyond the sensor resolution. Finally, a geometric map building method is presented and combined with the probabilistic approach. The resulting map is composed of two layers. The echo intensity layer holds the most likely echo intensities at each point in the sea-floor. The probabilistic layer contains information about how confident can the user or the higher control layers be about the echo intensity layer data. Experimental results have been conducted in a large subsea region.

  16. The modeling of a lunar visible side macrofigure

    Science.gov (United States)

    Nefedjev, Y.; Valeev, S.; Rizvanov, N.; Kutlenkov, M.; Varaksina, N.

    2009-04-01

    The task of a Moon macrofigure model construction, taken to its center of mass and axes of inertia, till now has not received the final decision. At present's research attempt of the Moon visible side model creation is made on the basis of space and ground supervisions. The methods of supervisions reception assumed a lunar objects binding to stars, so to celestial coordinates system. Like these supervisions the large-scale Moon pictures with stars have been used and the mission "Clementine" data. There were constructed five models on a program - analytical complex of Ulyanovsk st. tech. university. The analysis of sections for longitudes =-40 °,-20 °, 0 °, 20 °, 40 ° data catalogues of "Clementine", "Kazan-1", "Kiev" and catalogue "Kazan-2" gave the following results: 1. The comparison of five surface models hypsometric curve sections which are determined with "Clementine" data and catalogue "Kazan-2", and shows their very good consent. 2. The relief of catalogue macrofigure model "Kazan-2" gives neither definite descents, nor definite increases with respect to the space experiment "Clementine" data. 3. The comparison of hypsometric curve "Clementine" data and catalogues "Kazan-1", "Kiev" with "Kazan-2" also supports the early-made conclusions about the relief average level descent on "Kazan-1" data in comparison with "Kiev" data in northern Moon hemisphere, but the general descent has much less expressed form, than in catalogue "Kazan-1" and closer to descent size of space experiment supervision "Clementine" data.

  17. The amyloid stretch hypothesis: Recruiting proteins toward the dark side

    Science.gov (United States)

    Esteras-Chopo, Alexandra; Serrano, Luis; de la Paz, Manuela López

    2005-01-01

    A detailed understanding of the molecular events underlying the conversion and self-association of normally soluble proteins into amyloid fibrils is fundamental to the identification of therapeutic strategies to prevent or cure amyloid-related disorders. Recent investigations indicate that amyloid fibril formation is not just a general property of the polypeptide backbone depending on external factors, but that it is strongly modulated by amino acid side chains. Here, we propose and address the validation of the premise that the amyloidogenicity of a protein is indeed localized in short protein stretches (amyloid stretch hypothesis). We demonstrate that the conversion of a soluble nonamyloidogenic protein into an amyloidogenic prone molecule can be triggered by a nondestabilizing six-residue amyloidogenic insertion in a particular structural environment. Interestingly enough, although the inserted amyloid sequences clearly cause the process, the protease-resistant core of the fiber also includes short adjacent sequences from the otherwise soluble globular domain. Thus, short amyloid stretches accessible for intermolecular interactions trigger the self-assembly reaction and pull the rest of the protein into the fibrillar aggregate. The reliable identification of such amyloidogenic stretches in proteins opens the possibility of using them as targets for the inhibition of the amyloid fibril formation process. PMID:16263932

  18. Demand Side Management in Pellet Production: Internal and External Factors

    Science.gov (United States)

    Vigants, Haralds; Blumberga, Dagnija; Veidenbergs, Ivars

    2014-12-01

    This paper demonstrates a demand side management case study: how to save energy and how research and data analysis help to create an energy management system in a pellet production facility; and shows ways to implement the EU energy efficiency directive in production facilities. The study carried out in this research serves as a far-reaching step that can be taken to improve energy efficiency during the operation mode of technological equipment. The benchmarking methodology is used for analysis of results. Internal and external factors and indicators, which affect energy management potential in pellet production are analysed. Analysis of external factors is based on the state legal framework regulating the development of the energy sector. Methodology on the analysis of energy demand includes the internal energy management of an enterprise. The experimental results discussed in this paper show that particular steps, which are oriented to specific use of technological equipment, could play significant role in energy efficiency improvement in industry which is illustrated by the pre-milling process in the pellet production system using power.

  19. Blind Cartography for Side Channel Attacks: Cross-Correlation Cartography

    Directory of Open Access Journals (Sweden)

    Laurent Sauvage

    2012-01-01

    Full Text Available Side channel and fault injection attacks are major threats to cryptographic applications of embedded systems. Best performances for these attacks are achieved by focusing sensors or injectors on the sensible parts of the application, by means of dedicated methods to localise them. Few methods have been proposed in the past, and all of them aim at pinpointing the cryptoprocessor. However it could be interesting to exploit the activity of other parts of the application, in order to increase the attack's efficiency or to bypass its countermeasures. In this paper, we present a localisation method based on cross-correlation, which issues a list of areas of interest within the attacked device. It realizes an exhaustive analysis, since it may localise any module of the device, and not only those which perform cryptographic operations. Moreover, it also does not require a preliminary knowledge about the implementation, whereas some previous cartography methods require that the attacker could choose the cryptoprocessor inputs, which is not always possible. The method is experimentally validated using observations of the electromagnetic near field distribution over a Xilinx Virtex 5 FPGA. The matching between areas of interest and the application layout in the FPGA floorplan is confirmed by correlation analysis.

  20. Identification of side population cells in chicken embryonic gonads.

    Science.gov (United States)

    Bachelard, Elodie; Raucci, Franca; Montillet, Guillaume; Pain, Bertrand

    2015-02-01

    The side population (SP) phenotype, defined by the ability of a cell to efflux fluorescent dyes such as Hoechst, is common to several stem/progenitor cell types. In avian species, SP phenotype has been identified in pubertal and adult testes, but nothing is known about its expression during prenatal development of a male gonad. In this study, we characterized the Hoechst SP phenotype via the cytofluorimetric analysis of disaggregated testes on different days of chicken embryonic development. Male prenatal gonads contained a fraction of SP cells at each stage analyzed. At least two main SP fractions, named P3 and P4, were identified. The percentage of P3 fraction decreased as development proceeds, whereas P4 cell number was not affected by gonad growth. Functional inhibition of BCRP1 channel membrane using Verapamil and/or Ko143 showed that P3, but not P4 phenotype, was dependent on BCRP1 activity. Molecular analysis of both P3- and P4-sorted fractions revealed a differential RNA expression pattern, indicating that P3 cells mainly contained germinal stem cell markers, whereas P4 was preferentially composed of both Sertoli and Leydig cell progenitor markers. Finally, these findings provided evidence that the SP phenotype is a common feature of both germ and somatic cells detected in chicken developing testis.

  1. Electrostatic Self-Assembled Multilayers from Side Chain Azo Polyelectrolytes

    Institute of Scientific and Technical Information of China (English)

    庹新林; 陈峥; 邓永红; 王晓工; 刘德山

    2002-01-01

    Photoresponsive behavior and self-assembly properties of three side chain azo polyelectrolytes, poly (2-(4-phenylazophenoxy) ethanol-co-acrylic acid) (PPAPE), poly (2-(4-(4′-nitrophenylazo) phenoxy) ethanol-co-acrylic acid) (PNAPE), and poly (2-(4-(4′-ethoxyphenylazo) phenoxy) ethanol-co-acrylic acid) (PEAPE), were studied. These polyelectrolytes with different degrees of functionalization of azo chromophores were fabricated into nano-composite multilayers using two types of dipping solutions through a layer-by-layer electrostatic self-assembling process. Results show that the ratio between tetrahydrofuran (THF) and H2O significantly influences the photoresponsive behavior of PNAPE in THF-H2O mixture. The THF-H2O dipping solution, used in this work for self-assembly of hydrophobic polyelectrolytes, is proved to be as applicable as aqueous dipping solution for normal self-assembly of hydrophobic polyelectrolytes. However, significant differences in the multilayer growth between the two systems were also observed, which resulted from the remarkable difference of the existing forms of the polyelectrolytes in these two dipping solutions.

  2. Lock-on characteristics behind two side-by-side cylinders of diameter ratio two at small gap ratio

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Petry Y.R.; Lu, Wei-Ting; Chou, Shy-Tsin; Kuo, Cheng-Hsiung [National Chung Hsing University, Department of Mechanical Engineering, Taichung (China)

    2012-10-15

    The lock-on characteristics, the detailed interactions and downstream evolutions of the wakes behind side-by-side cylinders of unequal diameter (D/d = 2), spaced by a gap ratio 0.75 (G/D = 0.75), are investigated at Reynolds number 600 by the dye flow visualization, laser Doppler anemometry (LDA) and particle image velocimeter (PIV) velocity measurements. The lock-on frequency bands are studied by LDA and PIV at Reynolds number 2,000. The D, d and G are the diameters of the large, the small cylinders and the net gap between two cylinders, respectively. Periodic excitations, in form of rotary oscillation about the cylinder center, are applied to the large cylinder with the same amplitude. It is found that while the large cylinder is excited, two lock-on frequency bands of the wake behind the large cylinder are detected. These two lock-on frequency bands correspond to the primary and the one-third sub-harmonic lock-on of the wake behind large cylinder, respectively. These two lock-on frequency bands distribute symmetrically about the fundamental and the third superharmonic of the natural shedding frequency behind a single cylinder at the same Reynolds number. The left-shifted frequency band (1.8 {<=} f{sub e} /f{sub os} {<=} 2.0) is not considered as a locked-on frequency band because the phase difference between two excitation frequencies across f{sub e} /f{sub os} = 2.0 vary significantly. While the wake behind the large cylinder is locked-on at f{sub e} /3 (or f{sub os}), the gap flow becomes unbiased and the frequency of the wake behind small cylinder remains around the natural shedding frequency. Thus, the frequency band of 3.0 {<=} f{sub e} /f{sub os} {<=} 3.22 is also not locked-on because the phase difference in the narrow wake excited at f{sub e} /f{sub os} = 2.93 and 3.07 changes significantly. Note f{sub e} and f{sub os} denote the excitation frequency and the natural shedding frequency behind a single large cylinder, respectively. (orig.)

  3. Lock-on characteristics behind two side-by-side cylinders of diameter ratio two at small gap ratio

    Science.gov (United States)

    Lee, Petry Y. R.; Lu, Wei-Ting; Chou, Shy-Tsin; Kuo, Cheng-Hsiung

    2012-10-01

    The lock-on characteristics, the detailed interactions and downstream evolutions of the wakes behind side-by-side cylinders of unequal diameter ( D/ d = 2), spaced by a gap ratio 0.75 ( G/ D = 0.75), are investigated at Reynolds number 600 by the dye flow visualization, laser Doppler anemometry (LDA) and particle image velocimeter (PIV) velocity measurements. The lock-on frequency bands are studied by LDA and PIV at Reynolds number 2,000. The D, d and G are the diameters of the large, the small cylinders and the net gap between two cylinders, respectively. Periodic excitations, in form of rotary oscillation about the cylinder center, are applied to the large cylinder with the same amplitude. It is found that while the large cylinder is excited, two lock-on frequency bands of the wake behind the large cylinder are detected. These two lock-on frequency bands correspond to the primary and the one-third sub-harmonic lock-on of the wake behind large cylinder, respectively. These two lock-on frequency bands distribute symmetrically about the fundamental and the third superharmonic of the natural shedding frequency behind a single cylinder at the same Reynolds number. The left-shifted frequency band (1.8 ≤ f e / f os ≤ 2.0) is not considered as a locked-on frequency band because the phase difference between two excitation frequencies across f e / f os = 2.0 vary significantly. While the wake behind the large cylinder is locked-on at f e /3 (or f os ), the gap flow becomes unbiased and the frequency of the wake behind small cylinder remains around the natural shedding frequency. Thus, the frequency band of 3.0 ≤ f e / f os ≤ 3.22 is also not locked-on because the phase difference in the narrow wake excited at f e / f os = 2.93 and 3.07 changes significantly. Note f e and f os denote the excitation frequency and the natural shedding frequency behind a single large cylinder, respectively.

  4. Experimental studies of vertical mixing patterns in open channel flow generated by two delta wings side-by-side

    Science.gov (United States)

    Vaughan, Garrett

    Open channel raceway bioreactors are a low-cost system used to grow algae for biofuel production. Microalgae have many promises when it comes to renewable energy applications, but many economic hurdles must be overcome to achieve an economic fuel source that is competitive with petroleum-based fuels. One way to make algae more competitive is to improve vertical mixing in algae raceway bioreactors. Previous studies show that mixing may be increased by the addition of mechanisms such as airfoils. The circulation created helps move the algae from the bottom to top surface for necessary photosynthetic exchange. This improvement in light utilization allowed a certain study to achieve 2.2-2.4 times the amount of biomass relative to bioreactors without airfoils. This idea of increasing mixing in open channel raceways has been the focus of the Utah State University (USU) raceway hydraulics group. Computational Fluid Dynamics (CFD), Acoustic Doppler Velocimetry (ADV), and Particle Image Velocimetry (PIV) are all methods used at USU to computationally and experimentally quantify mixing in an open channel raceway. They have also been used to observe the effects of using delta wings (DW) in increasing vertical mixing in the raceway. These efforts showed great potential in the DW in increasing vertical mixing in the open channel bioreactor. However, this research begged the question, does the DW help increase algae growth? Three algae growth experiments comparing growth in a raceway with and without DW were completed. These experiments were successful, yielding an average 27.1% increase in the biomass. The DW appears to be a promising method of increasing algae biomass production. The next important step was to quantify vertical mixing and understand flow patterns due to two DWs side-by-side. Raceway channels are wider as they increase in size; and arrays of DWs will need to be installed to achieve quality mixing throughout the bioreactor. Quality mixing was attained for

  5. Double-Sided Opportunities Using Chemical Lift-Off Lithography.

    Science.gov (United States)

    Andrews, Anne M; Liao, Wei-Ssu; Weiss, Paul S

    2016-08-16

    We discuss the origins, motivation, invention, development, applications, and future of chemical lift-off lithography, in which a specified pattern of a self-assembled monolayer is removed, i.e., lifted off, using a reactive, patterned stamp that is brought into contact with the monolayer. For Au substrates, this process produces a supported, patterned monolayer of Au on the stamp in addition to the negative pattern in the original molecular monolayer. Both the patterned molecular monolayer on the original substrate and the patterned supported metal monolayer on the stamp are useful as materials and for further applications in sensing and other areas. Chemical lift-off lithography effectively lowers the barriers to and costs of high-resolution, large-area nanopatterning. On the patterned monolayer side, features in the single-nanometer range can be produced across large (square millimeter or larger) areas. Patterns smaller than the original stamp feature sizes can be produced by controlling the degree of contact between the stamp and the lifted-off monolayer. We note that this process is different than conventional lift-off processes in lithography in that chemical lift-off lithography removes material, whereas conventional lift-off is a positive-tone patterning method. Chemical lift-off lithography is in some ways similar to microtransfer printing. Chemical lift-off lithography has critical advantages in the preparation of biocapture surfaces because the molecules left behind are exploited to space and to orient functional(ized) molecules. On the supported metal monolayer side, a new two-dimensional material has been produced. The useful important chemical properties of Au (vis-à-vis functionalization with thiols) are retained, but the electronic and optical properties of bulk Au or even Au nanoparticles are not. These metal monolayers do not quench excitation and may be useful in optical measurements, particularly in combination with selective binding due to

  6. Different K{sup +}-Na{sup +} inter-diffusion kinetics between the air side and tin side of an ion-exchanged float aluminosilicate glass

    Energy Technology Data Exchange (ETDEWEB)

    Jiang Liangbao; Guo Xintao; Li Xiaoyu; Li Lei; Zhang Guanli [Beijing Institute of Aeronautical Materials, Beijing 100095 (China); Yan Yue, E-mail: Yue.Yan@biam.ac.cn [Beijing Institute of Aeronautical Materials, Beijing 100095 (China)

    2013-01-15

    Highlights: Black-Right-Pointing-Pointer The difference between the diffusion characteristics of K{sup +}-Na{sup +} ions in float glass on the air and tin sides was first demonstrated. Black-Right-Pointing-Pointer The diffusion coefficient is more sensitive to temperature and time on the tin than on the air sides. Black-Right-Pointing-Pointer The activation energy on the tin side is about three times larger than that on the air side. - Abstract: The difference between the inter-diffusion kinetics of K{sup +}-Na{sup +} in the air and tin sides of an ion-exchanged float aluminosilicate glass was investigated as a function of the exchange temperature and time. The potassium concentration profiles of the ion-exchanged glass surface were experimentally measured by electron microprobe analysis, and the diffusion coefficient was calculated by the Boltzmann-Montano approach. On the tin side of the ion-exchanged glass, the diffusion of K{sup +}-Na{sup +} ions is hindered by tin. The diffusion coefficient is also more sensitive to temperature and time on the tin than on the air sides. The results would be useful in guiding the strengthening process of float glass by one step ion-exchange or two step ion-exchange to obtain engineered stress profile (ESP) glasses.

  7. Exploring Tradeoffs in Demand-side and Supply-side Management of Urban Water Resources using Agent-based Modeling and Evolutionary Computation

    Science.gov (United States)

    Kanta, L.; Berglund, E. Z.

    2015-12-01

    Urban water supply systems may be managed through supply-side and demand-side strategies, which focus on water source expansion and demand reductions, respectively. Supply-side strategies bear infrastructure and energy costs, while demand-side strategies bear costs of implementation and inconvenience to consumers. To evaluate the performance of demand-side strategies, the participation and water use adaptations of consumers should be simulated. In this study, a Complex Adaptive Systems (CAS) framework is developed to simulate consumer agents that change their consumption to affect the withdrawal from the water supply system, which, in turn influences operational policies and long-term resource planning. Agent-based models are encoded to represent consumers and a policy maker agent and are coupled with water resources system simulation models. The CAS framework is coupled with an evolutionary computation-based multi-objective methodology to explore tradeoffs in cost, inconvenience to consumers, and environmental impacts for both supply-side and demand-side strategies. Decisions are identified to specify storage levels in a reservoir that trigger (1) increases in the volume of water pumped through inter-basin transfers from an external reservoir and (2) drought stages, which restrict the volume of water that is allowed for residential outdoor uses. The proposed methodology is demonstrated for Arlington, Texas, water supply system to identify non-dominated strategies for an historic drought decade. Results demonstrate that pumping costs associated with maximizing environmental reliability exceed pumping costs associated with minimizing restrictions on consumer water use.

  8. US-guided percutaneous transhepatic biliary drainage: comparative study of right-sided and left-sided approach

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Young Hwan; Cha, Soon Joo [College of Medicine, Inje Univ., Kimhae (Korea, Republic of)

    2002-02-01

    To compare the feasibility and safety of US-guided right and left percutaneous transhepatic biliary drainage (PTBD). Between March 1998 and May 1999, 32 patients underwent 36 US-guided right or left PTBD in referred order, alternatively. The causes of biliary obstruction were bile duct stone (n=2), bile duct carcinoma (n=10), carcinoma of the pancreas (n=9), GB carcinoma (n=7), metastasis to the porta hepatis (n=3), and carcinoma of the ampulla of vater (n=1). Technical success, procedure time, fluoroscopic time, and complications were evaluated. PTBD was successful in 94% of both right and left approach. The average procedure time was 9.7 {+-}3.8 min. in the right approach and 9.6 {+-}3.1 min. in the left approach, respectively (p=0.794). The average fluoroscopic time were 3.9{+-}2.4 min. in the right approach and 3.8{+-}2.2 min. in the left approach (p=0.892). A major complication, bile peritonitis, occurred in one of 16 patient with right-sided approach. Minor complications occurred in six right (2 hemobilia, 3 tube malfunction, 1 cholangitis) and three left (1 hemobilia, 1 fever, 1cholangitis) PTBD. There were no significant difference in the complication rates between right and left PTBD (p=0.729). There were no significant differences in feasibility and safety in US-guided right and left PTBD.

  9. GrayStarServer: Server-side spectrum synthesis with a browser-based client-side user interface

    CERN Document Server

    Short, C Ian

    2016-01-01

    I present GrayStarServer (GSS), a stellar atmospheric modeling and spectrum synthesis code of pedagogical accuracy that is accessible in any web browser on commonplace computational devices and that runs on a time-scale of a few seconds. The addition of spectrum synthesis annotated with line identifications extends the functionality and pedagogical applicability of GSS beyond that of its predecessor, GrayStar3 (GS3). The spectrum synthesis is based on a line list acquired from the NIST atomic spectra database, and the GSS post-processing and user interface (UI) client allows the user to inspect the plain text ASCII version of the line list, as well as to apply macroscopic broadening. Unlike GS3, GSS carries out the physical modeling on the server side in Java, and communicates with the JavaScript and HTML client via an asynchronous HTTP request. I also describe other improvements beyond GS3 such as more realistic modeling physics and use of the HTML element for higher quality plotting and rendering of result...

  10. Water and side-chain embedded π-turns.

    Science.gov (United States)

    Dasgupta, Bhaskar; Dey, Sucharita; Chakrabarti, Pinak

    2014-05-01

    Elucidating protein function from its structure is central to the understanding of cellular mechanisms. This involves deciphering the dependence of local structural motifs on sequence. These structural motifs may be stabilized by direct or water-mediated hydrogen bonding among the constituent residues. π-Turns, defined by interactions between (i) and (i + 5) positions, are large enough to contain a central space that can embed a water molecule (or a protein moiety) to form a stable structure. This work is an analysis of such embedded π-turns using a nonredundant dataset of protein structures. A total of 2965 embedded π-turns have been identified, as also 281 embedded Schellman motif, a type of π-turn which occurs at the C-termini of α-helices. Embedded π-turns and Schellman motifs have been classified on the basis of the protein atoms of the terminal turn residues that are linked by the embedded moiety, conformation, residue composition, and compared with the turns that have terminal residues connected by direct hydrogen bonds. Geometrically, the turns have been fitted to a circle and the position of the linker relative to its center analyzed. The hydroxyl group of Ser and Thr, located at (i + 3) position, is the most prominent linker for the side-chain mediated π-turns. Consideration of residue conservation among homologous sequences indicates the terminal and the linker positions to be the most conserved. The embedded π-turn as a binding site (for the linker) is discussed in the context of "nest," a concave depression that is formed in protein structures with adjacent residues having enantiomeric main-chain conformations.

  11. Reconstruction of endometrium from human endometrial side population cell lines.

    Directory of Open Access Journals (Sweden)

    Irene Cervelló

    Full Text Available Endometrial regeneration is mediated, at least in part, by the existence of a specialized somatic stem cell (SSC population recently identified by several groups using the side population (SP technique. We previously demonstrated that endometrial SP displays genotypic, phenotypic and the functional capability to develop human endometrium after subcutaneous injection in NOD-SCID mice. We have now established seven human endometrial SP (hESP cell lines (ICE 1-7: four from the epithelial and three from the stromal fraction, respectively. SP cell lines were generated under hypoxic conditions based on their cloning efficiency ability, cultured for 12-15 passages (20 weeks and cryopreserved. Cell lines displayed normal 46XX karyotype, intermediate telomerase activity pattern and expressed mRNAs encoding proteins that are considered characteristic of undifferentiated cells (Oct-4, GDF3, DNMT3B, Nanog, GABR3 and those of mesodermal origin (WT1, Cardiac Actin, Enolase, Globin, REN. Phenotype analysis corroborated their epithelial (CD9+ or stromal (vimentin+ cell origin and mesenchymal (CD90+, CD73+ and CD45⁻ attributes. Markers considered characteristic of ectoderm or endoderm were not detected. Cells did not express either estrogen receptor alpha (ERα or progesterone receptor (PR. The hESP cell lines were able to differentiate in vitro into adipocytes and osteocytes, which confirmed their mesenchymal origin. Finally, we demonstrated their ability to generate human endometrium when transplanted beneath the renal capsule of NOD-SCID mice. These findings confirm that SP cells exhibit key features of human endometrial SSC and open up new possibilities for the understanding of gynecological disorders such as endometriosis or Asherman syndrome. Our cell lines can be a valuable model to investigate new targets for endometrium proliferation in endometriosis.

  12. ITER Side Correction Coil Quench model and analysis

    Science.gov (United States)

    Nicollet, S.; Bessette, D.; Ciazynski, D.; Duchateau, J. L.; Gauthier, F.; Lacroix, B.

    2016-12-01

    Previous thermohydraulic studies performed for the ITER TF, CS and PF magnet systems have brought some important information on the detection and consequences of a quench as a function of the initial conditions (deposited energy, heated length). Even if the temperature margin of the Correction Coils is high, their behavior during a quench should also be studied since a quench is likely to be triggered by potential anomalies in joints, ground fault on the instrumentation wires, etc. A model has been developed with the SuperMagnet Code (Bagnasco et al., 2010) for a Side Correction Coil (SCC2) with four pancakes cooled in parallel, each of them represented by a Thea module (with the proper Cable In Conduit Conductor characteristics). All the other coils of the PF cooling loop are hydraulically connected in parallel (top/bottom correction coils and six Poloidal Field Coils) are modeled by Flower modules with equivalent hydraulics properties. The model and the analysis results are presented for five quench initiation cases with/without fast discharge: two quenches initiated by a heat input to the innermost turn of one pancake (case 1 and case 2) and two other quenches initiated at the innermost turns of four pancakes (case 3 and case 4). In the 5th case, the quench is initiated at the middle turn of one pancake. The impact on the cooling circuit, e.g. the exceedance of the opening pressure of the quench relief valves, is detailed in case of an undetected quench (i.e. no discharge of the magnet). Particular attention is also paid to a possible secondary quench detection system based on measured thermohydraulic signals (pressure, temperature and/or helium mass flow rate). The maximum cable temperature achieved in case of a fast current discharge (primary detection by voltage) is compared to the design hot spot criterion of 150 K, which includes the contribution of helium and jacket.

  13. Spontaneous biliary peritonitis: Is bed side diagnosis possible?

    Directory of Open Access Journals (Sweden)

    Vijai Datta Upadhyaya

    2013-01-01

    Full Text Available Background: Spontaneous biliary peritonitis is a rare cause of acute abdomen. In spontaneous biliary peritonitis there is perforation in the wall of the extra-hepatic or intra-hepatic duct occurs without any traumatic or iatrogenic injury and have been described more often in neonates. The symptoms may be acute or insidious delaying the diagnosis. Present manuscript deals with diagnosis and management of these cases. Materials and Methods: This is a prospective study and all patients of suspected biliary peritonitis presented during Dec 2010 to Feb 2012 were included in the study. After preliminary investigations in all patients abdominal paracentesis was done and in cases where intra-abdominal fluid bilirubin level was several fold higher than serum bilirubin level were subjected to exploratory laparotomy. Further investigation like T-tube cholangiogram and magnetic resonance cholangiopancreatography (MRCP was done to rule out choledochal cyst before leveling these cases as SPBD. Results: A total of 6 patients were included in present series commonest presenting symptom was progressive abdominal distension without signs of overt peritonitis followed by progressive jaundice, fever and abdominal pain. On exploration site of perforation was observed in 50% of cases and in 50% of cases bile duct was not dilated. Second surgery was not required in 34% of cases. There was no mortality or significant morbidity in our series. Conclusion: Spontaneous perforation of bile duct is rare disease and high index of suspicion is required for diagnosis. Simple bed side test can help in diagnosis but T tube cholangiogram or MRCP are must to rule out choledochal cyst.

  14. Flow Cytometry of the Side Population: Tips & Tricks

    Directory of Open Access Journals (Sweden)

    Irene Sales-Pardo

    2006-01-01

    Full Text Available Background: The Side Population (SP has become an important hallmark for the definition of the stem cell compartment, especially in the detection of these cells and in their physical isolation by fluorescence-activated cell sorting (FACS. SP cells are CD34neg and were discovered using ultraviolet excitation based on the efflux of Hoechst 33342 (Ho342. Although the method works as originally described, we believe that this method is difficult for most investigators. First, because the ability to discriminate SP cells is based on the differential retention of Ho342 during a functional assay; second, because of the difficulties in setting the right experimental and acquisition conditions; and third, because the analysis of the acquired data requires an extensive expertise on flow cytometry to accurately detect the SP events. Methods: First of all and mainly for the SP application, the laser beam paths were exhaustively checked to ensure the lowest coefficients of variation. Blood suspensions were prepared by erythrocyte lysis with ammonium chloride and hematopoietic cells were labeled with Ho342. Results: The Ho342 concentration and the staining procedure are critical for the optimal resolution of the SP cells. Although UV laser alignment is very important to resolve the dim tail that outlines the SP, the problem with Ho342 excitation is not the Hoechst Blue emission, but rather the Hoechst Red's (because of the weak emission. Conclusions: Each laboratory must establish its own expected ranges based on its instrument and results may vary slightly due to instrument differences such as the narrowness of the band pass filters, laser power, laser emission wavelength, nozzle type, differential of pressure, light collection system (cuvette versus jet-in-air and beam shaping optics.

  15. Preparing side charging of PCM storage: theoretical and experimental investigation

    Science.gov (United States)

    Tesfay, A. H.; Hagos, F. Y.; Yohannes, K. G.; Nydal, O. J.; Kahsay, M. B.

    2015-12-01

    In Ethiopia, there is an abundant source of solar energy that is estimated to 5.3 kWh/m2/day. However, more than 90% of the society uses biomass as a main source of energy for cooking due to lack of technologies to convert this energy. Replacing these cooking activities by using renewable energy resources decreases pollution and reduces deforestation significantly. Using the solar energy in day time has no problem. For night time however, the system needs some kind of back-up system to make the daytime solar energy available. This back-up should have high-density energy storage and constant working temperature to perform a specific application. Latent heat storage using phase change materials (PCM) is one way of storing thermal energy. In the current study, a latent heat storage that uses a PCM material is used to store the solar energy aimed at utilizing solar energy for cooking Injera, main staple bread in Ethiopia. The PCM is a mixture of 60% NaNO3 and 40% KNO3 that are known as solar salts. The storage has a welded parallel aluminum fins with a gap of 40 mm in between to enhance the thermal conductivity during the charging-discharging process of the storage. The fins are extruded outside of the storage container to enable a side charging technique for the PCM. A prototype was developed with a solar salt of 17.5 kg and is tested for charging-discharging. The numerical simulation done on ANSYS and experimental results show an agreement and the system registered a 41.6% efficiency.

  16. Study of the Comet C/2013 A1 (Siding Spring)

    Science.gov (United States)

    Vodniza, Alberto Q.; Pereira, Mario R.

    2014-11-01

    The comet called C/2013 A1 (SIDING SPRING) was discovered on January 3, 2013 in Australia. In January 28/2014, NASA announced that is preparing for the close encounter that will happen between the comet C/2013 A1 and Mars on October 19-2014. The Mission called “MAVEN” will insert in Mars orbit on september 21—2014. The comet will pass just 138,000 kilometers far from the surface of Mars. The probability that the comet collides with Mars is small but the dust particles emitted by the comet can cause damage to spacecrafts and probes that are in orbit around that planet. NASA is making preparations to take all precautions. If the comet is quite active, there will be almost no time to take security measures with Mars orbiters. For that reason NASA is already ahead of the facts. According to scientists of the "JET PROPULSION LABORATORY-JPL", dust particles spewing from the comet may be traveling at 56 km / sec in relation to the orbiters, fifty times faster than the speed of a bullet. From our Observatory, located in Pasto-Colombia, we captured several pictures, videos and astrometry data during several days. The pictures of the asteroid were captured with the following equipment: CGE PRO 1400 CELESTRON (f/11 Schmidt-Cassegrain Telescope) and STL-1001 SBIG camera. Astrometry was carried out, and we calculated the orbital elements.Summary And Conclusions: We obtained the following orbital parameters: eccentricity = 1.0003983, orbital inclination = 129.03078 deg, longitude of the ascending node = 300.99538 deg, argument of perihelion = 2.42310 deg, perihelion distance = 1.40023196 A.U. The parameters were calculated based on 20 observations (Jan 21 to April 02) with mean residual = 0.334 arcseconds. We also obtained the light curve of the body with our data (January to November/2014)Acknowledgements: The authors would like to thank to University of Narino-Pasto-Colombia.

  17. Relative x-ray backlighter intensity comparison of ti and ti/sc combination foils driven in double-sided and single-sided laser configuration

    Energy Technology Data Exchange (ETDEWEB)

    Bullock, A B; Landen, O L; Bradley, D K

    2000-06-05

    Use of multiple backlighter foils and/or double-sided laser interaction geometry with backlit imaging can result in improved backlighter efficiency. An experimental comparison of backlighter intensity for Ti foils and Ti/Sc combination foils in both the one-sided and double-sided laser-interaction configuration is presented. Spectrally-integrated framing camera images show intensity contributions of front and rear backlighter surfaces for both foil types. Analysis of time-resolved x-ray spectra collected from foil targets show the relative contribution of Ti and Sc 2-1 He-like resonance lines to the total backlighter intensity.

  18. Laterality and flight: concurrent tests of side-bias and optimality in flying tree swallows.

    Science.gov (United States)

    Mandel, James T; Ratcliffe, John M; Cerasale, David J; Winkler, David W

    2008-01-01

    Behavioural side-bias occurs in many vertebrates, including birds as a result of hemispheric specialization and can be advantageous by improving response times to sudden stimuli and efficiency in multi-tasking. However, behavioural side-bias can lead to morphological asymmetries resulting in reduced performance for specific activities. For flying animals, wing asymmetry is particularly costly and it is unclear if behavioural side-biases will be expressed in flight; the benefits of quick response time afforded by side-biases must be balanced against the costs of less efficient flight due to the morphological asymmetry side-biases may incur. Thus, competing constraints could lead to context-dependent expression or suppression of side-bias in flight. In repeated flight trials through an outdoor tunnel with obstacles, tree swallows (Tachycineta bicolor) preferred larger openings, but we did not detect either individual or population-level side-biases. Thus, while observed behavioural side-biases during substrate-foraging and copulation are common in birds, we did not see such side-bias expressed in obstacle avoidance behaviour in flight. This finding highlights the importance of behavioural context for investigations of side-bias and hemispheric laterality and suggests both proximate and ultimate trade-offs between species-specific cognitive ecology and flight biomechanics.

  19. Laterality and flight: concurrent tests of side-bias and optimality in flying tree swallows.

    Directory of Open Access Journals (Sweden)

    James T Mandel

    Full Text Available Behavioural side-bias occurs in many vertebrates, including birds as a result of hemispheric specialization and can be advantageous by improving response times to sudden stimuli and efficiency in multi-tasking. However, behavioural side-bias can lead to morphological asymmetries resulting in reduced performance for specific activities. For flying animals, wing asymmetry is particularly costly and it is unclear if behavioural side-biases will be expressed in flight; the benefits of quick response time afforded by side-biases must be balanced against the costs of less efficient flight due to the morphological asymmetry side-biases may incur. Thus, competing constraints could lead to context-dependent expression or suppression of side-bias in flight. In repeated flight trials through an outdoor tunnel with obstacles, tree swallows (Tachycineta bicolor preferred larger openings, but we did not detect either individual or population-level side-biases. Thus, while observed behavioural side-biases during substrate-foraging and copulation are common in birds, we did not see such side-bias expressed in obstacle avoidance behaviour in flight. This finding highlights the importance of behavioural context for investigations of side-bias and hemispheric laterality and suggests both proximate and ultimate trade-offs between species-specific cognitive ecology and flight biomechanics.

  20. Synthesis, surface characterization, and biointeraction studies of low-surface energy side-chain polyetherurethanes

    Science.gov (United States)

    Porter, Stephen Christopher

    1999-10-01

    New segmented polyetherurethanes (PEUs) with low surface energy hydrocarbon and fluorocarbon side-chains attached to the polymer hard segments were synthesized. The surface chemistry of solvent cast polymer films was studied using X-ray photoelectron spectroscopy, time-of-flight secondary ion mass spectrometry, and dynamic contact angle (DCA) measurements. Increases in the overall density and length of the alkyl side-chains within the PEUs resulted in greater side-chain concentrations at the polymer surface. PEUs bearing long alkyl (> C10 ) and perfluorocarbon side-chains were found to posses surfaces with highly enriched side-chain concentrations relative to the bulk polymer. In PEUs with significant side-chain surface enrichment, the relatively polar hard segment blocks were shown to reside in high concentrations just below the side-chain enriched surface layer. Furthermore, DCA measurements demonstrated that the surface of the alkyl side-chain PEUs did not undergo significant rearrangement when placed into an aqueous environment, whereas the surface of a hard segment model polymer bearing C18 sidechains (PEU-C18-HS) did. Hydrogen bonding within the PEUs was examined using FTIR and was shown to be disrupted by the addition of side-chains; an effect dependent on the density but not on the length of the side-chains. Heteropolymer blends comprised of mixtures of high side-chain density and side-chain free PEUs were compared with homopolymers having the same overall side-chain concentration as the blends. Significantly more surface enrichment of side-chains was found in the heteropolymer blends whereas hydrogen bonding nearly the same as in the homopolymers. Adsorption of native and delipidized human serum albumin (HSA) from pure solution and blood plasma; the elutabilty of adsorbed HSA; and static platelet adhesion to plasma preadsorbed surfaces, were all examined on alkyl side-chain PEUs. Several polymers with high C18 side-chain densities displayed increased