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Sample records for c f braun standard turbine island

  1. Performance comparison between transpiration air cooled turbine 3000 F (1649 C) stator vanes and solid uncooled vanes

    Science.gov (United States)

    Manning, G. B.; Moskowitz, S.; Cole, R.

    1984-06-01

    Testing was conducted to compare the aerodynamic performance of a turbine vane using transpiration air-cooling capable of operation at 3000 F (1649 C) gas temperature with a vane of identical profile with no cooling provisions to determine the effect of cooling on vane kinetic energy efficiency and loss coefficient. The test configuration was a 10-vane section of full scale first stagae turbien stator annulus designed for 1.6 pressure ratio, cooling air flow equal to 6.1 percent of primary flow, 3000 F (1649 C) turbine inlet temperature and primary-to-coolant temperature ratio of 2.7. To enable comparison with other investigations, tests were conducted at three pressure ratios from 1.4 to 1.6, three coolant flows from 75 to 120 percent of design, and three primary-to-coolant temperature ratios from 2.70 to 1.15. Efficiency, loss coefficent and flow capacity test results were in good agreement with predicted values for both the transpiration air cooled and uncooled vanes. The testing demonstrated that it is necessary to conduct test evaluations of transpiration air-cooled components at or near design coolant-to-gas stream temperature ratio in order to achieve correct results.

  2. Resultados neonatais no parto vaginal espontâneo comparados aos dos partos com fórcipe de Simpson-Braun em primíparas Neonatal outcome of spontaneous deliveries as compared to Simpson-Braun forceps deliveries in nulliparous women

    Directory of Open Access Journals (Sweden)

    Belmiro Gonçalves Pereira

    2004-02-01

    Full Text Available OBJETIVO: comparar os resultados neonatais dos partos vaginais espontâneos ou assistidos com fórcipe de Simpson-Braun em nulíparas. MÉTODO: em estudo de corte retrospectivo foram avaliados dois grupos de primíparas atendidas no Centro Obstétrico do CAISM/UNICAMP, que tiveram parto vaginal sob analgesia epidural. O grupo fórcipe foi formado por 119 pacientes que tiveram parto a fórcipe de Simpson-Braun, e o grupo normal por 114 casos de parto vaginal espontâneo. Foram estudadas as variáveis neonatais imediatas como o estado do líquido amniótico e os índices de Apgar, assim como a evolução neonatal nos primeiros dias de vida. Para análise estatística foram utilizados os testes c², exato de Fisher e t de Student para comparação de médias e considerada significativa a diferença correspondente a pPURPOSE: to compare maternal and neonatal outcomes between spontaneous vaginal and Simpson-Braun forceps deliveries in nulliparous women. METHOD: a retrospective study including two groups of nulliparous women, who had vaginal delivery under peridural anesthesia in the obstetric unit of the CAISM-UNICAMP: the forceps group included 119 women who had Simpson-Braun forceps delivery, and the normal group included 114 women who delivered spontaneously. Neonatal outcomes, such as Apgar score and the evolution in the first days of life, were studied. Data were compared in both groups and, for statistical analysis, c² test, Fisher exact, and Student t tests were used. The differences were considered significant when p<0.05. RESULTS: the indications for Simpson-Braun forceps delivery were maternal-fetal relief (90 cases and abbreviation of the expulsive period (29 cases. In the forceps group there were 8 cases (6.7% of vaginal injuries; a similar result was observed in the normal group. The number of hospitalization days for the parturient and the newborns was identical, 2.4 days. The newborns in the two groups had similar Apgar scores

  3. Offshore Wind Turbines - Estimated Noise from Offshore Wind Turbine, Monhegan Island, Maine: Environmental Effects of Offshore Wind Energy Development

    Energy Technology Data Exchange (ETDEWEB)

    Aker, Pamela M.; Jones, Anthony M.; Copping, Andrea E.

    2010-11-23

    Deep C Wind, a consortium headed by the University of Maine will test the first U.S. offshore wind platforms in 2012. In advance of final siting and permitting of the test turbines off Monhegan Island, residents of the island off Maine require reassurance that the noise levels from the test turbines will not disturb them. Pacific Northwest National Laboratory, at the request of the University of Maine, and with the support of the U.S. Department of Energy Wind Program, modeled the acoustic output of the planned test turbines.

  4. Gas turbine control for islanding operation of distribution systems

    DEFF Research Database (Denmark)

    Mahat, Pukar; Chen, Zhe; Bak-Jensen, Birgitte

    2009-01-01

    Danish distribution systems are characterized by a significant penetration of small gas turbine generators (GTGs) and fixed speed wind turbine generators (WTGs). Island operation of these distribution systems are becoming a viable option for economical and technical reasons. However, stabilizing...... frequency in an islanded system is one of the major challenges. This paper presents three different gas turbine governors for possible operation of distribution systems in an islanding mode. Simulation results are presented to show the performance of these governors in grid connected and islanding mode....

  5. European wind turbine standards 2 (EWTS-2)

    Energy Technology Data Exchange (ETDEWEB)

    Pierik, J.T.G.; Dekker, J.W.M.; Braam, H. [and others

    1999-03-01

    A summary is given of the main results of the European Wind Turbine Standards II project. EWTS-II was completed in 1998 and included investigations on: 1) wind farms-wind field and turbine loading; 2) complex terrain and fatigue loading; 3) extreme wind conditions; 4) quantification of failure probabilities; 5) integration of blade tests in design; 6) power performance in complex terrain; 7) site evaluation. In addition to these scientific evaluations, the EWTS-II participants established an organization of qualified measuring institute in the field of wind energy, the MEASNET organization. MEASNET unified measurement procedures of the participating institutes and guarantees qualified measurements and mutual acceptance among its members. (LN)

  6. Von Braun Fountain

    Science.gov (United States)

    1999-01-01

    A fountain representing a rocket launch was dedicated in the Von Braun courtyard outside of Building 4200 at Marshall Space Flight Center during the weekend celebrating the 30th arniversary of the Apollo 11 lunar landing. On hand for the festivities were many of the Saturn and Apollo astronauts.

  7. Advanced Micro Turbine System (AMTS) -C200 Micro Turbine -Ultra-Low Emissions Micro Turbine

    Energy Technology Data Exchange (ETDEWEB)

    Capstone Turbine Corporation

    2007-12-31

    In September 2000 Capstone Turbine Corporation commenced work on a US Department of Energy contract to develop and improve advanced microturbines for power generation with high electrical efficiency and reduced pollutants. The Advanced MicroTurbine System (AMTS) program focused on: (1) The development and implementation of technology for a 200 kWe scale high efficiency microturbine system (2) The development and implementation of a 65 kWe microturbine which meets California Air Resources Board (CARB) emissions standards effective in 2007. Both of these objectives were achieved in the course of the AMTS program. At its conclusion prototype C200 Microturbines had been designed, assembled and successfully completed field demonstration. C65 Microturbines operating on natural, digester and landfill gas were also developed and successfully tested to demonstrate compliance with CARB 2007 Fossil Fuel Emissions Standards for NOx, CO and VOC emissions. The C65 Microturbine subsequently received approval from CARB under Executive Order DG-018 and was approved for sale in California. The United Technologies Research Center worked in parallel to successfully execute a RD&D program to demonstrate the viability of a low emissions AMS which integrated a high-performing microturbine with Organic Rankine Cycle systems. These results are documented in AMS Final Report DOE/CH/11060-1 dated March 26, 2007.

  8. SiC/SiC Leading Edge Turbine Airfoil Tested Under Simulated Gas Turbine Conditions

    Science.gov (United States)

    Robinson, R. Craig; Hatton, Kenneth S.

    1999-01-01

    Silicon-based ceramics have been proposed as component materials for use in gas turbine engine hot-sections. A high pressure burner rig was used to expose both a baseline metal airfoil and ceramic matrix composite leading edge airfoil to typical gas turbine conditions to comparatively evaluate the material response at high temperatures. To eliminate many of the concerns related to an entirely ceramic, rotating airfoil, this study has focused on equipping a stationary metal airfoil with a ceramic leading edge insert to demonstrate the feasibility and benefits of such a configuration. Here, the idea was to allow the SiC/SiC composite to be integrated as the airfoil's leading edge, operating in a "free-floating" or unrestrained manner. and provide temperature relief to the metal blade underneath. The test included cycling the airfoils between simulated idle, lift, and cruise flight conditions. In addition, the airfoils were air-cooled, uniquely instrumented, and exposed to the same internal and external conditions, which included gas temperatures in excess of 1370 C (2500 F). Results show the leading edge insert remained structurally intact after 200 simulated flight cycles with only a slightly oxidized surface. The instrumentation clearly suggested a significant reduction (approximately 600 F) in internal metal temperatures as a result of the ceramic leading edge. The object of this testing was to validate the design and analysis done by Materials Research and Design of Rosemont, PA and to determine the feasibility of this design for the intended application.

  9. Field Demonstration of Aviation Turbine Fuel MIL-T-83133C, Grade JP-8 (NATO Code F-34), at Fort Bliss, TX

    Science.gov (United States)

    1992-09-01

    Howitzer. SYP, MI09A2, M109A3 8 L Tank. Combat MIAI 9 Cavalry Fighting Vehicle M3 10 Truck. Carlo . 2-1/2 Ton M35AI, M35A2. M35A2C. M36A2 21 Carrier. C.P...Southwest Research Institute, San Antonio, TX, January 1985. 12. A.F. Montemayor , L.L. Stavinoha, and S.J. Lestz, "Potential Benefits from the Use of JP

  10. Electroluminescent TCC, C3dg and fB/Bb epitope assays for profiling complement cascade activation in vitro using an activated complement serum calibration standard.

    Science.gov (United States)

    van Vuuren, B Jansen; Bergseth, G; Mollnes, T E; Shaw, A M

    2014-01-15

    Electroluminescent assays for epitopes on the complement components C3dg, terminal complement complex (TCC) and factor B/Bb (fB/Bb) have been developed with capture and detection antibodies to produce detection limits C3dg=91±9ng/mL, TCC=3±0.1ng/mL and fB=55.7±0.1ng/mL. The assay performance was assessed against a series of zymosan and heat aggregated IgG (HAIgG) in vitro activations of complement using a calibrated activated complement serum (ACS) as calibration standard. The ACS standard was stable within 20% accuracy over a 6-month period with freeze-thaw cycles as required. Differential activation of the complement cascade was observed for TCC showing a pseudo-first order formation half-life of 3.5h after activation with zymosan. The C3dg activation fragment indicates a 10% total activation for both activation agents. The kinetic-epitope analysis for fB indicates that the capture epitope is on the fB/Bb protein fragment which can then become covered by the formation of C3bBb or C3bBbP complexes during the time course of the cascade. Copyright © 2013 Elsevier B.V. All rights reserved.

  11. Wind turbine generator interaction with conventional diesel generators on Block Island, Rhode Island. Volume 1. Executive summary

    Energy Technology Data Exchange (ETDEWEB)

    Wilreker, V.F.; Stiller, P.H.; Scott, G.W.; Kruse, V.J.; Smith, R.F.

    1984-02-01

    This report summarizes the primary results of a three-part study involving the effects of connecting a MOD-OA wind turbine generator to an isolated diesel power system. The subject utility is that owned and operated by the Block Island Power Company (BIPCO). The MOD-OA installation here was the third of four experimental nominal 200 kW wind turbines connected to various utilities under the Federal Wind Energy Program. The BIPCO installation was characterized by the highest wind energy penetration levels of four sites and, as such, was adjudged the best candidate for conducting the data acquisition and analysis effort that is the subject of this study. The three-phases of the study analysis address: (1) fuel displacement, (2) dynamic interaction, and (3) three modes of reactive power control. These analyses all have as their basis the results of the data acquisition program conducted during 1982 from February into April on Block Island, Rhode Island.

  12. Contribution to a dynamic wind turbine model validation from a wind farm islanding experiment

    DEFF Research Database (Denmark)

    Pedersen, Jørgen Kaas; Pedersen, Knud Ole Helgesen; Poulsen, Niels Kjølstad

    2003-01-01

    Measurements from an islanding experiment on the Rejsby Hede wind farm, Denmark, are used for the validation of the dynamic model of grid-connected, stall-controlled wind turbines equipped with induction generators. The simulated results are found to be in good agreement with the measurements...... and possible discrepancies are explained. The work with the wind turbine model validation relates to the dynamic stability investigations on incorporation of large amount of wind power in the Danish power grid, where the dynamic wind turbine model is applied....

  13. Rapid Measurement of Emissions From Military Aircraft Turbine Engines by Downstream Extractive Sampling of Aircraft on the Ground: Results for C-130 and F-15 Aircraft (POSTPRINT)

    Science.gov (United States)

    2009-02-01

    g, Ram Hashmonay g a SpiceAir Consulting, 2703 Mt. Holyoke Rd., Columbus, OH 43221, USA b Scientific Consulting, 4781 Teter Ct., Columbus, OH 4320 ...and for the F-15 tests the probes were 3 m above ground level. Both gas and aerosol probes were 1.27 cm diameter stainless steel tubes that extended to

  14. Standard guide for use of thermocouples in creep and stress-rupture testing to 1800°F (1000°C) in air

    CERN Document Server

    American Society for Testing and Materials. Philadelphia

    2000-01-01

    1.1 This guide covers the use of ANSI thermocouple Types K, N, R, and S for creep and stress-rupture testing at temperatures up to 1800°F (1000°C) in air at one atmosphere of pressure. It does not cover the use of sheathed thermocouples. 1.2 The values stated in inch-pound units are to be regarded as the standard. The values given in parentheses are for information only. 1.3This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety and health practices and determine the applicability of regulatory limitations prior to use.

  15. Control strategies for gas turbine generators for grid connected and islanding operations

    DEFF Research Database (Denmark)

    Mahat, Pukar; Chen, Zhe; Bak-Jensen, Birgitte

    2010-01-01

    fine while a DG is connected to a grid, might not work as desired while it is islanded and vise versa. This paper presents a strategy to operate distribution systems with a small gas turbine generator (GTG), which is capable of supplying local loads, in both islanding and grid connected conditions......Islanding operation of distribution systems with distributed generations (DG) is becoming a viable option for economical and technical reasons. However, there are various issues to be resolved before it can be a reality. One of the main issues is control of the DG. Control strategies, that may work....... Separate strategies are used to control the GTG while it is connected to the grid and while it is islanded. Switching between the control strategies is achieved through a state detection algorithm that includes islanding and grid re-connection detections. An existing islanding detection technique has been...

  16. Research and Development of Mixed and Standard Type Biomass Gas Turbine System with Enhanced Fuel Applicability

    National Research Council Canada - National Science Library

    MATSUBARA, Koji; TAMAI, Hiroki; TANUMA, Hayato; MATSUDAIRA, Yusaku; DAS, Piyali; ACHARJEE, Paltu; MORIMOTO, Sousuke

    2015-01-01

    .... This paper describes a mixed and standard type gas turbine system for this purpose. The mixed type gas turbine employs a regenerated Brayton cycle with a secondary combustor to burn various fuels...

  17. Dr. von Braun Briefing Walt Disney

    Science.gov (United States)

    1965-01-01

    Dr. von Braun began his association with Walt Disney in the 1950s when the rocket scientist appeared in three Disney television productions related to the exploration of space. Years later, Dr. von Braun invited Disney and his associates to tour the Marshall Space Flight Center (MSFC) in Huntsville, Alabama. This photograph is dated April 13, 1965. From left are R.J. Schwinghamer from the MSFC, Disney, B.J. Bernight, and Dr. von Braun.

  18. Atmospheric histories and growth trends of C4F10, C5F12, C6F14, C7F16 and C8F18

    Directory of Open Access Journals (Sweden)

    R. F. Weiss

    2012-05-01

    Full Text Available Atmospheric observations and trends are presented for the high molecular weight perfluorocarbons (PFCs: decafluorobutane (C4F10, dodecafluoropentane (C5F12, tetradecafluorohexane (C6F14, hexadecafluoroheptane (C7F16 and octadecafluorooctane (C8F18. Their atmospheric histories are based on measurements of 36 Northern Hemisphere and 46 Southern Hemisphere archived air samples collected between 1973 to 2011 using the Advanced Global Atmospheric Gases Experiment (AGAGE "Medusa" preconcentration gas chromatography-mass spectrometry systems. A new calibration scale was prepared for each PFC, with estimated accuracies of 6.8% for C4F10, 7.8% for C5F12, 4.0% for C6F14, 6.6% for C7F16 and 7.9% for C8F18. Based on our observations the 2011 globally averaged dry air mole fractions of these heavy PFCs are: 0.17 parts-per-trillion (ppt, i.e., parts per 1012 for C4F10, 0.12 ppt for C5F12, 0.27 ppt for C6F14, 0.12 ppt for C7F16 and 0.09 ppt for C8F18. These atmospheric mole fractions combine to contribute to a global average radiative forcing of 0.35 mW m−2, which is 6% of the total anthropogenic PFC radiative forcing (Montzka and Reimann, 2011; Oram et al., 2012. The growth rates of the heavy perfluorocarbons were largest in the late 1990s peaking at 6.2 parts per quadrillion (ppq, i.e., parts per 1015 per year (yr for C4F10, at 5.0 ppq yr−1 for C5F12 and 16.6 ppq yr−1 for C6F14 and in the early 1990s for C7F16 at 4.7 ppq yr−1 and in the mid 1990s for C8F18 at 4.8 ppq yr−1. The 2011 globally averaged mean atmospheric growth rates of these PFCs are subsequently lower at 2.2 ppq yr−1 for C4F10, 1.4 ppq yr−1 for C5F12, 5.0 ppq yr−1 for C6F14, 3.4 ppq yr−1 for C7F16 and 0.9 ppq yr−1 for C8F18. The more recent slowdown in the growth rates suggests that emissions are declining as compared to the 1980s and 1990s.

  19. New algorithm for islanding detection of wind turbines driven DFIG

    Energy Technology Data Exchange (ETDEWEB)

    Mirzaei, Jaber [Monenco Consulting Engineering Company, Tehran (Iran, Islamic Republic of). Dept. of Wind Energy; Kargar, H. Kazemi [Shahid Beheshti Univ., Tehran (Iran, Islamic Republic of). Dept. of Electrical and Computer Engineering

    2011-07-01

    This paper proposes a new algorithm for islanding condition of working in various wind farm loading conditions which is a combination of both passive and active methods for islanding detection of wind farm. The passive part detects probability of islanding conditions and the active part examines and verifies this probable conditions. The buses voltage, first and second order frequency derivation are the parameters which are used in passive part of algorithm and capacitance variations of capacitor banks are employed in active part. This new method was validated by simulation results of Manjil wind farm located in Manjil, Iran. (orig.)

  20. System Identification for the Clipper Liberty C96 Wind Turbine

    Science.gov (United States)

    Showers, Daniel

    System identification techniques are powerful tools that help improve modeling capabilities of real world dynamic systems. These techniques are well established and have been successfully used on countless systems in many areas. However, wind turbines provide a unique challenge for system identification because of the difficulty in measuring its primary input: wind. This thesis first motivates the problem by demonstrating the challenges with wind turbine system identification using both simulations and real data. It then suggests techniques toward successfully identifying a dynamic wind turbine model including the notion of an effective wind speed and how it might be measured. Various levels of simulation complexity are explored for insights into calculating an effective wind speed. In addition, measurements taken from the University of Minnesota's Clipper Liberty C96 research wind turbine are used for a preliminary investigation into the effective wind speed calculation and system identification of a real world wind turbine.

  1. Islanding Control Architecture in future smart grid with both demand and wind turbine control

    DEFF Research Database (Denmark)

    Chen, Yu; Xu, Zhao; Østergaard, Jacob

    2013-01-01

    In recent years, a large number of Distributed Generation units (DG units) such as Wind Turbines (WTs) and Combined Heat and Power plants (CHPs) have been penetrating the distribution systems. Meanwhile, an intentional island operation of distribution systems is proposed as a potential measure...... against power supply outages by continuously running DG units during system emergencies. However, there are some challenging security issues for an island operation, such as the power imbalance during the islanding transition and the coordination of feeder protection systems. To tackle the former issue......, which is the focus of this paper, available resources including both DG units and demand should be fully utilized as reserves. The control and coordination among different resources requires an integral architecture to serve the purpose. This paper develops the Islanding Control Architecture (ICA...

  2. Dr. von Braun With German Rocket Experimenters

    Science.gov (United States)

    1930-01-01

    Dr. von Braun was among a famous group of rocket experimenters in Germany in the 1930s. This photograph is believed to be made on the occasion of Herman Oberth's Kegelduese liquid rocket engine being certified as to performance during firing. From left to right are R. Nebel, Dr. Ritter, Mr. Baermueller, Kurt Heinish, Herman Oberth, Klaus Riedel, Wernher von Braun, and an unidentified person.

  3. Dr. von Braun With Management Team

    Science.gov (United States)

    1961-01-01

    Dr. von Braun is shown in this photograph, which was probably taken in the early 1960s, with members of his management team. Pictured from left to right are, Werner Kuers, Director of the Manufacturing Engineering Division; Dr. Walter Haeussermarn, Director of the Astrionics Division; Dr. William Mrazek, Propulsion and Vehicle Engineering Division; Dr. von Braun; Dieter Grau, Director of the Quality Assurance Division; Dr. Oswald Lange, Director of the Saturn Systems Office; and Erich Neubert , Associate Deputy Director for Research and Development.

  4. Standards for measurements and testing of wind turbine power quality

    Energy Technology Data Exchange (ETDEWEB)

    Soerensen, P. [Risoe National Lab., Roskilde (Denmark); Gerdes, G.; Klosse, R.; Santjer, F. [DEWI, Wilhelmshaven (Germany); Robertson, N.; Davy, W. [NEL, Glasgow (United Kingdom); Koulouvari, M.; Morfiadakis, E. [CRES, Pikermi (Greece); Larsson, Aa. [Chalmers Univ. of Technology, Goeteborg (Sweden)

    1999-03-01

    The present paper describes the work done in power quality sub-task of the project `European Wind Turbine Testing Procedure Developments` funded by the EU SMT program. The objective of the power quality sub-task has been to make analyses and new recommendation(s) for the standardisation of measurement and verification of wind turbine power quality. The work has been organised in three major activities. The first activity has been to propose measurement procedures and to verify existing and new measurement procedures. This activity has also involved a comparison of the measurements and data processing of the participating partners. The second activity has been to investigate the influence of terrain, grid properties and wind farm summation on the power quality of wind turbines with constant rotor speed. The third activity has been to investigate the influence of terrain, grid properties and wind farm summation on the power quality of wind turbines with variable rotor speed. (au)

  5. Study on Modelling Standardization of Double-fed Wind Turbine and Its Application

    Directory of Open Access Journals (Sweden)

    Li Xiang

    2016-01-01

    Full Text Available Based on the standardized modelling of the International Modelling Team, study on double-fed induction generator (DFIG wind turbine is processed in this paper, aiming at capability of universally and reasonably reflecting key performance related to large scale system analysis. The standardized model proposed is of high degree of structural modularity, easy functional extension and universalization of control strategy and signal. Moreover, it is applicable for wind turbines produced by different manufacturers through model parameter adjustment. The complexity of the model can meet both needs of grid-connected characteristic simulation of wind turbine and large scale power system simulation.

  6. 10 October 2013 - D. Braun First Deputy Minister for Regional Development, Czech Republic, P. Styczeń Deputy Minister of Transport, Construction and Maritime Economy, Republic of Poland and F. Palko State Secretary, Ministry of Transport, Construction and Regional Development, Slovak Republic visiting the LHC tunnel at Point 1 with Technology Department, Vacuum, Surfaces and Coatings Group Leader J. M. Jimenez and signing the Guest book with CERN Director-General R. Heuer

    CERN Multimedia

    Anna Pantelia

    2013-01-01

    10 October 2013 - D. Braun First Deputy Minister for Regional Development, Czech Republic, P. Styczeń Deputy Minister of Transport, Construction and Maritime Economy, Republic of Poland and F. Palko State Secretary, Ministry of Transport, Construction and Regional Development, Slovak Republic visiting the LHC tunnel at Point 1 with Technology Department, Vacuum, Surfaces and Coatings Group Leader J. M. Jimenez and signing the Guest book with CERN Director-General R. Heuer

  7. Comparison of Standard Wind Turbine Models with Vendor Models for Power System Stability Analysis: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Honrubia-Escribano, A.; Gomez Lazaro, E.; Jimenez-Buendia, F.; Muljadi, Eduard

    2016-11-01

    The International Electrotechnical Commission Standard 61400-27-1 was published in February 2015. This standard deals with the development of generic terms and parameters to specify the electrical characteristics of wind turbines. Generic models of very complex technological systems, such as wind turbines, are thus defined based on the four common configurations available in the market. Due to its recent publication, the comparison of the response of generic models with specific vendor models plays a key role in ensuring the widespread use of this standard. This paper compares the response of a specific Gamesa dynamic wind turbine model to the corresponding generic IEC Type III wind turbine model response when the wind turbine is subjected to a three-phase voltage dip. This Type III model represents the doubly-fed induction generator wind turbine, which is not only one of the most commonly sold and installed technologies in the current market but also a complex variable-speed operation implementation. In fact, active and reactive power transients are observed due to the voltage reduction. Special attention is given to the reactive power injection provided by the wind turbine models because it is a requirement of current grid codes. Further, the boundaries of the generic models associated with transient events that cannot be represented exactly are included in the paper.

  8. Aquantis C-Plane Ocean Current Turbine Project

    Energy Technology Data Exchange (ETDEWEB)

    Fleming, Alex [Dehlsen Associates, LLC, Santa Barbara, CA (United States)

    2015-09-16

    The Aquantis 2.5 MW Ocean Current Generation Device technology developed by Dehlsen Associates, LLC (DA) is a derivation of wind power generating technology (a means of harnessing a slow moving fluid) adapted to the ocean environment. The Aquantis Project provides an opportunity for accelerated technological development and early commercialization, since it involves the joining of two mature disciplines: ocean engineering and wind turbine design. The Aquantis Current Plane (C-Plane) technology is an ocean current turbine designed to extract kinetic energy from a current flow. The technology is capable of achieving competitively priced, continuous, base-load, and reliable power generation from a source of renewable energy not before possible in this scale or form.

  9. Gusts and Shear Within Hurricane Eyewalls Can Exceed Offshore Wind-Turbine Design Standards

    CERN Document Server

    Worsnop, Rochelle P; Bryan, George H; Damiani, Rick; Musial, Walt

    2016-01-01

    Offshore wind energy development is underway in the U.S., with proposed sites located in hurricane-prone regions. Turbine design criteria outlined by the International Electrotechnical Commission do not encompass the extreme wind speeds and directional shifts of hurricanes stronger than a Category 2. We examine the most turbulent portion of a hurricane (the eyewall) using large-eddy simulations with Cloud Model 1 (CM1). Gusts and mean wind speeds near the eyewall exceed the current design threshold of 50 m s-1 mean wind and 70 m s-1 gusts for Class I turbines. Gust factors are greatest at the eye-eyewall interface. Further, shifts in wind direction at wind turbine hub height suggest turbines must rotate into the wind faster than current practice. Although current design standards omit mention of wind direction change across the rotor layer, large values (15-50 deg) suggest that veer should be considered in design standards.

  10. 33 CFR 110.128c - Island of Kauai, Hawaii.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Island of Kauai, Hawaii. 110.128c Section 110.128c Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.128c Island of Kauai, Hawaii. (a) Nawiliwili Bay. The...

  11. Ion chemistry in octafluorocyclobutane, c-C 4F 8

    Science.gov (United States)

    Jiao, C. Q.; Garscadden, A.; Haaland, P. D.

    1998-11-01

    Cross-sections for electron impact ionization of octafluorocyclobutane ( c-C 4F 8) have been measured from 10 to 200 eV by Fourier transform mass spectrometry. No parent ion is observed, and over half of the dissociative ionization yields C 2F 4+ and C 3F 5+. Eleven other fluorocarbon cations are produced with smaller cross-sections, giving a total ionization cross-section of (1.6±0.2)×10 -15 cm 2 between 80 and 200 eV. Only CF 2+ and C 2F 3+ react further with the parent molecule to yield C 3F 5+ as the primary product. No evidence of cationic polymerization was found. F - and C 4F 8- are formed by electron attachment at energies below 10 eV, but neither reacts further with c-C 4F 8.

  12. 78 FR 39057 - Environmental Impact Statement: T.F. Green Airport, Warwick, Rhode Island

    Science.gov (United States)

    2013-06-28

    ... Federal Aviation Administration Environmental Impact Statement: T.F. Green Airport, Warwick, Rhode Island... Environmental Impact Statement has been prepared for Theodore Francis Green Airport in Warwick, Rhode Island..., Rhode Island. The Re-Evaluation and ROD is available for review during normal business hours at the...

  13. Von Braun Rocket Team at Fort Bliss, Texas

    Science.gov (United States)

    1940-01-01

    The German Rocket Team, also known as the Von Braun Rocket Team, poses for a group photograph at Fort Bliss, Texas. After World War II ended in 1945, Dr. Wernher von Braun led some 120 of his Peenemuende Colleagues, who developed the V-2 rocket for the German military during the War, to the United Sttes under a contract to the U.S. Army Corps as part of Operation Paperclip. During the following five years the team worked on high altitude firings of the captured V-2 rockets at the White Sands Missile Range in New Mexico, and a guided missile development unit at Fort Bliss, Texas. In April 1950, the group was transferred to the Army Ballistic Missile Agency (ABMA) at Redstone Arsenal in Huntsville, Alabama, and continued to work on the development of the guided missiles for the U.S. Army until transferring to a newly established field center of the National Aeronautic and Space Administration (NASA), George C. Marshall Space Flight Center (MSFC).

  14. Portrait of Dr. Von Braun with Walt Disney, 1954.

    Science.gov (United States)

    1954-01-01

    Marshall Center Director Dr. Wernher Von Braun is pictured with Walt Disney during a visit to the Marshall Space Flight Center in 1954. In the 1950s, Dr. Von Braun while working in California on the Saturn project, also worked with Disney studios as a technical director in making three films about Space Exploration for television. Disney's tour of Marshall in 1965 was Von Braun's hope for a renewed public interest in the future of the Space Program at NASA.

  15. la teoría del desarrollo desigual de Óscar Braun. Un análisis critico

    Directory of Open Access Journals (Sweden)

    Wright Phil

    1979-12-01

    Full Text Available

    En este análisis crítico de la teoría del intercambio desigual de Oscar Braun, intentamos movernos consistentemente a través de un número de etapas analíticas distintas. Estas etapas son: a una discusión sobre el objeto del conocimiento en Braun, sin las restricciones de su propia problemática (sección 3; b una confrontación del objeto del conocímiento en Braun con el objeto real o concreto (sección4, y c una crítica a] objeto del conocimiento en Braun (secciones 2 y 5. La crítica del objeto del conocimiento en Braun se divide en dos partes ya que tratamos con dos problemas analíticos distintos: a la teoría del intercambio desigual puede estar representada como una teoría del imperialismo, y b la naturaleza del objeto del conocimiento contenida en la teoría del intercambio desigual de Braun es la que causa los problemas y la que lo lleva a constituirla como una teoría del imperialismo.

  16. The odontological identification of Eva Braun Hitler.

    Science.gov (United States)

    Keiser-Nielsen, S; Strøm, F

    1983-01-01

    On May 7th-9th, 1945, a team of Russian pathologists autopsied several bodies found in and near the Fuehrer Bunker in Berlin; among them, a female body (No. 13) was later identified as that of Eva Braun Hitler (EBH), mainly by means of a gold bridge from the lower right jaw. A postmortem photograph of this bridge also shows a separate gold filling. Data now available on the dental treatment of EBH have permitted the present authors to substantiate that this gold filling also came from the mouth of EBH. Further speculation about the fate of EBH would henceforth seem professionally unfounded.

  17. Gusts and shear within hurricane eyewalls can exceed offshore wind turbine design standards

    Science.gov (United States)

    Worsnop, Rochelle P.; Lundquist, Julie K.; Bryan, George H.; Damiani, Rick; Musial, Walt

    2017-06-01

    Offshore wind energy development is underway in the U.S., with proposed sites located in hurricane-prone regions. Turbine design criteria outlined by the International Electrotechnical Commission do not encompass the extreme wind speeds and directional shifts of hurricanes stronger than category 2. We examine a hurricane's turbulent eyewall using large-eddy simulations with Cloud Model 1. Gusts and mean wind speeds near the eyewall of a category 5 hurricane exceed the current Class I turbine design threshold of 50 m s-1 mean wind and 70 m s-1 gusts. Largest gust factors occur at the eye-eyewall interface. Further, shifts in wind direction suggest that turbines must rotate or yaw faster than current practice. Although current design standards omit mention of wind direction change across the rotor layer, large values (15-50°) suggest that veer should be considered.

  18. Victor or Villain? Wernher von Braun and the Space Race

    Science.gov (United States)

    O'Brien, Jason L.; Sears, Christine E.

    2011-01-01

    Set during the Cold War and space race, this historical role-play focuses on Wernher von Braun's involvement in and culpability for the use of slave laborers to produce V-2 rockets for Nazi Germany. Students will grapple with two central questions. Should von Braun have been allowed to emigrate to the United States given his affiliation with the…

  19. Thermal tests of the SGT5-4000F gas-turbine plant of the PGU-420T power-generating unit at Combined Heat And Power Plant 16 of Mosenergo

    Science.gov (United States)

    Teplov, B. D.; Radin, Yu. A.; Filin, A. A.; Rudenko, D. V.

    2016-08-01

    In December 2014, the PGU-420T power-generating unit was put into operation at the Combined Heat and Power Plant 16, an affiliated company of PAO Mosenergo. In 2014-2015, thermal tests of the SGT5- 4000F gas-turbine plant (GTP) integrated into the power-generating unit were carried out. In the article, the test conditions are described and the test results are presented and analyzed. During the tests, 92 operating modes within a wide range of electrical loads and ambient air temperatures and operating conditions of the GTP when fired with fuel oil were investigated. In the tests, an authorized automated measuring system was applied. The experimental data were processed according to ISO 2314:2009 "Gas turbines—Acceptance tests" standard. The available capacity and the GTP efficiency vary from 266 MW and 38.8% to 302 MW and 39.8%, respectively, within the ambient air temperature range from +24 to-12°C, while the turbine inlet temperature decreases from 1200 to 1250°C. The switch to firing fuel oil results in a reduction in the turbine inlet temperature and the capacity of the GTP. With the full load and a reduction in the ambient temperature from +24 to-12°C, the compressor efficiency decreases from 89.6 to 86.4%. The turbine efficiency is approximately 89-91%. Within the investigated range of power output, the emissions of nitrogen oxides do not exceed 35 ppm for the gas-fired plant and 65 ppm for the fuel-oil-fired plant. Within the range of the GTP power output from 50 to 100% of the rated output, the combustion chamber operates without underburning and with hardly any CO being formed. At low loads close to the no-load operation mode, the CO emissions drastically increase.

  20. 46 CFR Appendix F to Subpart C to... - Sample Worker Certification Form

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Sample Worker Certification Form F Appendix F to Subpart C to Part 197 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE OCCUPATIONAL SAFETY AND HEALTH STANDARDS GENERAL PROVISIONS Benzene Pt. 197, Subpt. C, App. F Appendix F to Subpart C...

  1. Automated electric control of a vertical axis wind turbine in island operation

    OpenAIRE

    Högberg, Lars

    2009-01-01

    At the Division of Electricity at Uppsala University, a wind power concept has been developed. The concept uses a vertical axis wind turbine with a direct driven generator. The turbine has fixed blades, making speed control the only way to regulate power absorption. The speed is controlled with the electric load. The turbine is not self-starting, but can be started using the generator as a motor. In this project, an unsupervised electric system with automatic control is designed and construct...

  2. Cogeneration steam turbines from Siemens: New solutions

    Science.gov (United States)

    Kasilov, V. F.; Kholodkov, S. V.

    2017-03-01

    The Enhanced Platform system intended for the design and manufacture of Siemens AG turbines is presented. It combines organizational and production measures allowing the production of various types of steam-turbine units with a power of up to 250 MWel from standard components. The Enhanced Platform designs feature higher efficiency, improved reliability, better flexibility, longer overhaul intervals, and lower production costs. The design features of SST-700 and SST-900 steam turbines are outlined. The SST-700 turbine is used in backpressure steam-turbine units (STU) or as a high-pressure cylinder in a two-cylinder condensing turbine with steam reheat. The design of an SST-700 single-cylinder turbine with a casing without horizontal split featuring better flexibility of the turbine unit is presented. An SST-900 turbine can be used as a combined IP and LP cylinder (IPLPC) in steam-turbine or combined-cycle power units with steam reheat. The arrangements of a turbine unit based on a combination of SST-700 and SST-900 turbines or SST-500 and SST-800 turbines are presented. Examples of this combination include, respectively, PGU-410 combinedcycle units (CCU) with a condensing turbine and PGU-420 CCUs with a cogeneration turbine. The main equipment items of a PGU-410 CCU comprise an SGT5-4000F gas-turbine unit (GTU) and STU consisting of SST-700 and SST-900RH steam turbines. The steam-turbine section of a PGU-420 cogeneration power unit has a single-shaft turbine unit with two SST-800 turbines and one SST-500 turbine giving a power output of N el. STU = 150 MW under condensing conditions.

  3. Fast control strategy for stabilising fixed-speed induction-generator-based wind turbines in an islanded distributed system

    DEFF Research Database (Denmark)

    Wei, Mu; Chen, Zhe

    2013-01-01

    Distributed generation systems (DGS) with fixed-speed induction-generator-based wind turbines (FSWT) are sensitive and vulnerable to voltage disturbances and reactive power deficiency. Consequently, the control and protection strategies for such a DGS should be prompt and precise to avoid undesired...... wind generator cutting off. This study investigates and analyses the dynamic characteristics of an FSWT to reveal the behaviours of an FSWT under disturbances. Then a fast control strategy for stabilising an islanded DGS is proposed. The main contributions of the control strategy are: the total amount...

  4. Columnar islands in Barrett's esophagus: Do they impact Prague C&M criteria and dysplasia grade?

    Science.gov (United States)

    Epstein, Jeremy A; Cosby, Hilary; Falk, Gary W; Khashab, Mouen A; Kiesslich, Ralf; Montgomery, Elizabeth A; Wang, Jean S; Canto, Marcia Irene

    2017-09-01

    The standard for classifying Barrett's metaplasia on endoscopy, the Prague C&M criteria, ignores all islands of metaplastic-appearing tissue. The aims of the present study were to measure the prevalence of columnar islands, quantify their impact on metaplasia extent, and determine if they harbor advanced dysplasia. Data from two prospective patient cohorts were retrospectively analyzed. They included adults who underwent upper endoscopy to evaluate for gastroesophageal reflux disease, Barrett's esophagus (BE), dysplasia, or adenocarcinoma between 2003 and 2012 at tertiary care centers in the USA and Germany. The BE pattern, location, and pathology were examined. The extent of BE as defined by the Prague criteria (disregarding the location of islands) was compared with the complete maximal extent of BE (incorporating the location of islands). A total of 555 patients underwent endoscopy (mean age 60.1 years, 67.2% male, 91.9% white). Among those patients, 191 (34.4%) showed metaplastic-appearing mucosa in islands. Endoscopically, in 101 (52.9%) cases, islands were proximal to the farthest segment of BE as defined by the Prague M location. Histologically, intestinal metaplasia was confirmed in 60 (58.8%) of the 102 esophagogastroduodenoscopies (EGDs) where islands were biopsied. In 41 (40.2%) cases, the histologically confirmed BE islands extended farther than the maximal segment based on the Prague criteria. Pathology from biopsies of islands either changed the diagnosis or worsened the BE dysplasia grade in 16 (15.7%) of the 102 patients. Columnar islands are commonly seen on EGD. The Prague C&M criteria may underestimate the maximal extent of BE and overlook the area of highest dysplasia grade. © 2017 Journal of Gastroenterology and Hepatology Foundation and John Wiley & Sons Australia, Ltd.

  5. Dr. von Braun and Army Ballistics Missile Agency (ABMA) Group

    Science.gov (United States)

    1959-01-01

    This photograph of Dr. von Braun, shown here to the left of General Bruce Medaris, was taken in the fall of 1959, immediately prior to Medaris' retirement from the Army. At the time, von Braun and his associates worked for the Army Ballistics Missile Agency in Huntsville, Alabama. Those in the photograph have been identified as Ernst Stuhlinger, Frederick von Saurma, Fritz Mueller, Hermarn Weidner, E.W. Neubert (partially hidden), W.A. Mrazek, Karl Heimburg, Arthur Rudolph, Otto Hoberg, von Braun, Oswald Lange, Medaris, Helmut Hoelzer, Hans Maus, E.D. Geissler, Hans Heuter, and George Constan.

  6. Investigation of the IEC Safety Standard for Small Wind Turbine Design Through Modeling and Testing: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Jonkman, J.; van Dam, J.; Forsyth, T.; Davis, D.

    2003-01-01

    Since 1999, the International Electrotechnical Commission (IEC) Maintenance Team 2 (MT2) has been working on a revision of the IEC 61400-2 standard on the safety, quality, integrity, and design requirements of small wind turbines (SWTs). During this effort, a study was conducted to evaluate the quality of the structural design criteria specified by the original 2 standard. Test measurements and aeroelastic predictions of loads were gathered for a collection of SWTs and evaluated against the simplified load models and load cases specified in the standard. The collection of turbines included variations in rotor size, blade number, rotor location (upwind/downwind), hub type (rigid/teetered), yaw mechanism (free/active), and others. In general, the comparison of load measurements and model predictions exemplified the inaccuracy of the design load levels in the original -2 standard and suggested methods of improvement. Revisions being made to the standard include enhanced load models, new load cases, and improved safety factors. This work should culminate in a revised IEC 61400-2 standard that has a higher degree of applicability and dependability than the original.

  7. Development of Advanced Environmental Barrier Coatings for SiC/SiC Ceramic Matrix Composites: Path Toward 2700 F Temperature Capability and Beyond

    Science.gov (United States)

    Zhu, Dongming; Harder, Bryan; Hurst, Janet B.; Good, Brian; Costa, Gustavo; Bhatt, Ramakrishna T.; Fox, Dennis S.

    2017-01-01

    Advanced environmental barrier coating systems for SiC-SiC Ceramic Matrix Composite (CMC) turbine and combustor hot section components are currently being developed to meet future turbine engine emission and performance goals. One of the significant coating development challenges is to achieve prime-reliant environmental barrier coating systems to meet the future 2700F EBC-CMC temperature stability and environmental durability requirements. This presentation will emphasize recent NASA environmental barrier coating system testing and down-selects, particularly the development path and properties towards 2700-3000F durability goals by using NASA hafnium-hafnia-rare earth-silicon-silicate composition EBC systems for the SiC-SiC CMC turbine component applications. Advanced hafnium-based compositions for enabling next generation EBC and CMCs capabilities towards ultra-high temperature ceramic coating systems will also be briefly mentioned.

  8. Low cycle fatigue numerical estimation of a high pressure turbine disc for the AL-31F jet engine

    Directory of Open Access Journals (Sweden)

    Spodniak Miroslav

    2017-01-01

    Full Text Available This article deals with the description of an approximate numerical estimation approach of a low cycle fatigue of a high pressure turbine disc for the AL-31F turbofan jet engine. The numerical estimation is based on the finite element method carried out in the SolidWorks software. The low cycle fatigue assessment of a high pressure turbine disc was carried out on the basis of dimensional, shape and material disc characteristics, which are available for the particular high pressure engine turbine. The method described here enables relatively fast setting of economically feasible low cycle fatigue of the assessed high pressure turbine disc using a commercially available software. The numerical estimation of accuracy of a low cycle fatigue depends on the accuracy of required input data for the particular investigated object.

  9. Low cycle fatigue numerical estimation of a high pressure turbine disc for the AL-31F jet engine

    Science.gov (United States)

    Spodniak, Miroslav; Klimko, Marek; Hocko, Marián; Žitek, Pavel

    This article deals with the description of an approximate numerical estimation approach of a low cycle fatigue of a high pressure turbine disc for the AL-31F turbofan jet engine. The numerical estimation is based on the finite element method carried out in the SolidWorks software. The low cycle fatigue assessment of a high pressure turbine disc was carried out on the basis of dimensional, shape and material disc characteristics, which are available for the particular high pressure engine turbine. The method described here enables relatively fast setting of economically feasible low cycle fatigue of the assessed high pressure turbine disc using a commercially available software. The numerical estimation of accuracy of a low cycle fatigue depends on the accuracy of required input data for the particular investigated object.

  10. Does modified Braun enteroenterostomy improve alkaline reflux gastritis and marginal ulcer after pancreaticoduodenectomy?

    Science.gov (United States)

    Su, An-Ping; Ke, Neng-Wen; Zhang, Yi; Wang, Wei-Guo; Zhang, Zhao-Da; Liu, Xu-Bao; Hu, Wei-Ming; Tian, Bo-Le

    2013-11-01

    The safety of pancreaticoduodenectomy has improved significantly. However, alkaline reflux gastritis and marginal ulcer are two substantial problems after pancreaticoduodenectomy. To identify whether Child reconstruction with a modified Braun enteroenterostomy decreases the incidence of alkaline reflux gastritis and marginal ulcer after pancreaticoduodenectomy better than Roux-en-Y reconstruction. Data on 57 consecutive patients who underwent standard pancreaticoduodenectomy between January 1, 2008 and January 31, 2012 were collected prospectively. Data on early and late complications of the Child reconstruction with a modified Braun enteroenterostomy and Roux-en-Y were gathered. The risk factors of alkaline reflux gastritis and marginal ulcer were also investigated by using univariate and multivariate analyses. Twenty-five patients received Roux-en-Y and 32 underwent Child reconstruction with a modified Braun enteroenterostomy. Early complications after the two reconstruction methods were insignificant. Significant differences in terms of later postoperative morbidity (P = 0.01) and change in body mass index (P = 0.03) were found 12 months after pancreaticoduodenectomy. No significant difference for alkaline reflux gastritis was observed between the two methods (14.8 vs. 28.6 %, P = 0.24). Marginal ulcer occurred significantly lower in patients with the modified reconstruction than in those with Roux-en-Y reconstruction (11.1 vs. 47.6 %, P = 0.01). Peptic ulcer history, diabetes mellitus, and reconstruction type had a significant effect on marginal ulcer formation. Child reconstruction with a modified Braun enteroenterostomy offers an advantage with respect to marginal ulcer after standard pancreaticoduodenectomy, potentially decreasing the incidence of alkaline reflux gastritis as effectively as Roux-en-Y reconstruction.

  11. Nondissociative low-energy electron attachment to SF6, C6F6, C10F8, and c-C7F14: Negative ion lifetimes

    Science.gov (United States)

    Suess, L.; Parthasarathy, R.; Dunning, F. B.

    2002-12-01

    The lifetimes of long-lived parent anions formed by nondissociative electron attachment to SF6, C6F6, C10F8, and c-C7F14 are investigated. The ions are created via electron transfer in collisions with K(np) Rydberg atoms and their lifetimes determined by observing their decay using a Penning ion trap. The measured lifetimes vary widely from target to target and range from ˜10 μs for C6F6- to ˜10 ms for SF6-. The present results are compared with values obtained in earlier free-electron studies.

  12. Feasible application of offshore wind turbines in Labuan Island, Sabah for energy complementary

    Science.gov (United States)

    Salleh, Nur Farahin; Chew, Boon Cheong; Hamid, Syaiful Rizal

    2017-03-01

    Nowadays, the world energy requirements are increasing at an alarming rate and the power demand is running ahead of supply. It is widely recognized that the fossil fuels such as coal, petroleum and natural gas are presently being used for electricity generation. Therefore, in future it may not be sufficient to keep pace with ever increasing demand of the electrical energy of the world. The renewable energy can provide clean sources of energy which is reliable and secure to society. This paper analyzed renewable energy adoption, focusing on offshore wind turbines. In this case study, Labuan, Sabah has been selected and suggested as the location to install the offshore wind turbines because of geographical advantage of the South China Sea. The technology is expected to provide great power energy with least environment impact and high sustainability as it is located within the windy area with no terrain features, buildings or other obstruction. This study used qualitative methods for both data collection and data analysis. This study proved the feasible application of offshore wind turbines in the South China Sea, Sabah produced the complementary energy to fossil fuels. Hence, the offshore wind turbines might become one of main energy sources in Sabah. The application of the offshore wind turbines to Sabah residential area develops a lot of benefit and support Malaysian government goal which is to be more competitive in renewable energy generation while sustaining national economic growth.

  13. New high profitable wind turbines

    Energy Technology Data Exchange (ETDEWEB)

    Frankovic, Bernard [Rijeka Univ., Faculty of Engineering, Rijeka (Croatia); Vrsalovic, Ivan [Rijekaprojekt d.o.o., Rijeka (Croatia)

    2001-11-01

    To generate more quantities of electric energy from wind it is necessary to use a new type of wind turbine built in the regulable mantle's nozzle. This wind turbine type replaces the free air stream from wind by a programmed, i.e. regulated, and partially concentrated stream of air. The nozzle shell is designed as an aerodynamically shaped ring with wings with its lower pressure side pointed towards the centre so that the lift force on each part of the wing is directed radially towards the centre. This induces centrifugal reaction force in the airflow that causes the stream field to expand strongly downstream of the rotor and includes a greater number of streamlines in the active stream in front of the rotor (upstream). Thus the nozzle forces a higher mass flow rate of air through the turbine. The higher mass flow and higher velocity reduction behind the rotor result in a higher energy output from the wind turbine in the nozzle. In this way the wind turbine efficiency is multiplied. New turbines induce more power from weaker and medium winds and their lasting time, because of the relation p = f(v{sup 3}) (i.e. the power corresponds to wind velocity raised to third power). Wind turbine nozzle produces three times more energy than conventional wind turbine. Short economic analysis for conditions of the island of Lastovo indicates that profit gained by new turbines is up to five times higher than by conventional turbines. The new wind turbine nozzle should generate interest and demand on an international market, even for regions with weaker winds. (Author)

  14. Energisation of Wind Turbine Transformers with an Auxiliary Generator in a Large Offshore Wind Farm Under Islanded Operation

    DEFF Research Database (Denmark)

    Arana Aristi, Iván; Hernandez, Alvaro; Thumm, Gerhard

    2011-01-01

    The prospective inrush currents during the energization of wind turbine transformers in a large offshore wind farm during islanded operation were estimated by time-domain simulations covering different energizing scenarios. In this way, worst case procedures could be identified. The energization...... of the farm was carried out by an auxiliary diesel-driven synchronous generator placed on the offshore platform. The available information from all of the components and excitation control was implemented in PSCAD-EMTDC. The results from the simulations were compared with the capability curves and current...... limits of the synchronous generator. Based on the worst possible transformer energization scenario, an optimized procedure to reduce the loading of the auxiliary generator during transient conditions has been proposed based on the reduced generator terminal voltage, automatic voltage regulator parameters...

  15. Assessment of C-Type Darrieus Wind Turbine Under Low Wind Speed Condition

    Science.gov (United States)

    Misaran, M. S.; Rahman, Md. M.; Muzammil, W. K.; Ismail, M. A.

    2017-07-01

    Harvesting wind energy in in a low wind speed region is deem un-economical if not daunting task. Study shows that a minimum cut in speed of 3.5 m/s is required to extract a meaningful wind energy for electricity while a mean speed of 6 m/s is preferred. However, in Malaysia the mean speed is at 2 m/s with certain potential areas having 3 m/s mean speed. Thus, this work aims to develop a wind turbine that able to operate at lower cut-in speed and produce meaningful power for electricity generation. A C-type Darrieus blade is selected as it shows good potential to operate in arbitrary wind speed condition. The wind turbine is designed and fabricated in UMS labs while the performance of the wind turbine is evaluated in a simulated wind condition. Test result shows that the wind turbine started to rotate at 1 m/s compared to a NACA 0012 Darrieus turbine that started to rotate at 3 m/s. The performance of the turbine shows that it have good potential to be used in an intermittent arbitrary wind speed condition as well as low mean wind speed condition.

  16. Langage C manuel de référence

    CERN Document Server

    Harbison, Samuel P

    1990-01-01

    Traduction de la seconde édition d'un ouvrage de référence de réputation internationale, tenant compte de la proposition de normalisation ANSI C. Plus de 180 fonctions standards sont présentées et les plus récentes extensions du langage sont décrites : affectations de structure, type de données énumération, type de données "void".

  17. Preliminary studies on the reaction of growing geese (Anser anser f. domestica) to the proximity of wind turbines.

    Science.gov (United States)

    Mikolajczak, J; Borowski, S; Marć-Pieńkowska, J; Odrowaz-Sypniewska, G; Bernacki, Z; Siódmiak, J; Szterk, P

    2013-01-01

    Wind farms produce electricity without causing air pollution and environmental degradation. Unfortunately, wind turbines are a source of infrasound, which may cause a number of physiological effects, such as an increase in cortisol and catecholamine secretion. The impact of infrasound noise, emitted by wind turbines, on the health of geese and other farm animals has not previously been evaluated. Therefore, the aim of this study was to determine the effect of noise, generated by wind turbines, on the stress parameters (cortisol) and the weight gain of geese kept in surrounding areas. The study consisted of 40 individuals of 5-week-old domestic geese Anser anser f domestica, divided into 2 equal groups. The first experimental gaggle (I) remained within 50 m from turbine and the second one (II) within 500 m. During the 12 weeks of the study, noise measurements were also taken. Weight gain and the concentration of cortisol in blood were assessed and significant differences in both cases were found. Geese from gaggle I gained less weight and had a higher concentration of cortisol in blood, compared to individuals from gaggle II. Lower activity and some disturbing changes in behavior of animals from group I were noted. Results of the study suggest a negative effect of the immediate vicinity of a wind turbine on the stress parameters of geese and their productivity.

  18. Dr. Space the life of Wernher von Braun

    CERN Document Server

    Ward, Bob

    2013-01-01

    Written by veteran aerospace journalist Bob Ward, who spent years investigating his subject, this biography presents a revealing but even-handed portrait of the father of modern rocketry. As he chronicles Wernher von Braun's life, Ward explodes many myths and misconceptions about the controversial genius who was a hero to some, a villain to others. The picture of von Braun that emerges is of a brilliant scientist with limitless curiosity and a drive to achieve his goals at almost any price from, developing the world's first ballistic missile used against the Allies in World War II to help

  19. Validation of the Standard Method for Assessing Flicker From Wind Turbines

    DEFF Research Database (Denmark)

    Barahona Garzon, Braulio; Sørensen, Poul Ejnar; Christensen, L.

    2011-01-01

    . This study is based on the data from two wind farms, one with fixed-speed wind turbines and one with variable-speed wind turbines. The data are: a type test at the terminals of a wind turbine, and measurements at the connection of a collection line to the substation. The type test data are used to assess...

  20. Conservation status of Dendrobium tenuicaule Hook. f. (Orchidaceae, a Middle Andaman Island endemic, India

    Directory of Open Access Journals (Sweden)

    B.R.P. Rao

    2012-12-01

    Full Text Available The current distribution and threat assessment of Dendrobium tenuicaule Hook. f. (Orchidaceae, an endemic orchid of Middle Andaman Island is presented here. New data available from field surveys indicated the species is Critically Endangered as per the 2001 IUCN Red List Catagories and Criteria.

  1. Probabilistic Analysis of a SiC/SiC Ceramic Matrix Composite Turbine Vane

    Science.gov (United States)

    Murthy, Pappu L. N.; Nemeth, Noel N.; Brewer, David N.; Mital, Subodh

    2004-01-01

    To demonstrate the advanced composite materials technology under development within the Ultra-Efficient Engine Technology (UEET) Program, it was planned to fabricate, test, and analyze a turbine vane made entirely of silicon carbide-fiber-reinforced silicon carbide matrix composite (SiC/SiC CMC) material. The objective was to utilize a five-harness satin weave melt-infiltrated (MI) SiC/SiC composite material developed under this program to design and fabricate a stator vane that can endure 1000 hours of engine service conditions. The vane was designed such that the expected maximum stresses were kept within the proportional limit strength of the material. Any violation of this design requirement was considered as the failure. This report presents results of a probabilistic analysis and reliability assessment of the vane. Probability of failure to meet the design requirements was computed. In the analysis, material properties, strength, and pressure loading were considered as random variables. The pressure loads were considered normally distributed with a nominal variation. A temperature profile on the vane was obtained by performing a computational fluid dynamics (CFD) analysis and was assumed to be deterministic. The results suggest that for the current vane design, the chance of not meeting design requirements is about 1.6 percent.

  2. Anomalous variations of NmF2 over the Argentine Islands: a statistical study

    Directory of Open Access Journals (Sweden)

    A. V. Pavlov

    2009-04-01

    Full Text Available We present a statistical study of variations in the F2-layer peak electron density, NmF2, and altitude, hmF2, over the Argentine Islands ionosonde. The critical frequencies, foF2, and, foE, of the F2 and E-layers, and the propagation factor, M(3000F2, measured by the ionosonde during the 1957–1959 and 1962–1995 time periods were used in the statistical analysis to determine the values of NmF2 and hmF2. The probabilities to observe maximum and minimum values of NmF2 and hmF2 in a diurnal variation of the electron density are calculated. Our study shows that the main part of the maximum diurnal values of NmF2 is observed in a time sector close to midnight in November, December, January, and February exhibiting the anomalous diurnal variations of NmF2. Another anomalous feature of the diurnal variations of NmF2 exhibited during November, December, and January when the minimum diurnal value of NmF2 is mainly located close to the noon sector. These anomalous diurnal variations of NmF2 are found to be during both geomagnetically quiet and disturbed conditions. Anomalous features are not found in the diurnal variations of hmF2. The statistical study of the NmF2 winter anomaly phenomena over the Argentine Islands ionosonde was carried out. The variations in a maximum daytime value, R, of a ratio of a geomagnetically quiet daytime winter NmF2 to a geomagnetically quiet daytime summer NmF2 taken at a given UT and for approximately the same level of solar activity were studied. The conditional probability of the occurrence of R in an interval of R, the most frequent value of R, the mean expected value of R, and the conditional probability to observe the F2-region winter anomaly during a daytime period were calculated for low, moderate, and high solar activity. The calculations show that the mean expected value of R and the occurrence frequency of the F2-region winter anomaly increase with increasing solar activity.

  3. Measured effects of wind turbine generation at the Block Island Power Company

    Science.gov (United States)

    Wilreker, V. F.; Smith, R. F.; Stiller, P. H.; Scot, G. W.; Shaltens, R. K.

    1984-01-01

    Data measurements made on the NASA MOD-OA 200-kw wind-turbine generator (WTG) installed on a utility grid form the basis for an overall performance analysis. Fuel displacement/-savings, dynamic interactions, and WTG excitation (reactive-power) control effects are studied. Continuous recording of a large number of electrical and mechanical variables on FM magnetic tape permit evaluation and correlation of phenomena over a bandwidth of at least 20 Hz. Because the wind-power penetration reached peaks of 60 percent, the impact of wind fluctuation and wind-turbine/diesel-utility interaction is evaluated in a worst-case scenario. The speed-governor dynamics of the diesel units exhibited an underdamped response, and the utility operation procedures were not altered to optimize overall WTG/utility performance. Primary findings over the data collection period are: a calculated 6.7-percent reduction in fuel consumption while generating 11 percent of the total electrical energy; acceptable system voltage and frequency fluctuations with WTG connected; and applicability of WTG excitation schemes using voltage, power, or VARS as the controlled variable.

  4. Scaling of size distributions of C60 and C70 fullerene surface islands

    Science.gov (United States)

    Dubrovskii, V. G.; Berdnikov, Y.; Olyanich, D. A.; Mararov, V. V.; Utas, T. V.; Zotov, A. V.; Saranin, A. A.

    2017-06-01

    We present experimental data and a theoretical analysis for the size distributions of C60 and C70 surface islands deposited onto In-modified Si(111)√3 × √3-Au surface under different conditions. We show that both fullerene islands feature an analytic Vicsek-Family scaling shape where the scaled size distributions are given by a power law times an incomplete beta-function with the required normalization. The power exponent in this distribution corresponds to the fractal shape of two-dimensional islands, confirmed by the experimentally observed morphologies. Quite interestingly, we do not see any significant difference between C60 and C70 fullerenes in terms of either scaling parameters or temperature dependence of the diffusion constants. In particular, we deduce the activation energy for surface diffusion of ED = 140 ± 10 meV for both types of fullerenes.

  5. Underlag till en standard för teknisk isolering

    OpenAIRE

    Dahlén, Pär

    2014-01-01

    Vid upphandling inom offentlig sektor eller större företag kan användandet av standarder vara ett viktigt redskap för att säkerställa att en produkt eller tjänst uppfyller de krav som verksamheten ställer när det gäller exempelvis kvalitet, kostnader och effekter på miljön. Stigande priser på energi och en ökad insikt om samhällets negativa inverkan på miljön gör att energieffektiviseringar blivit ett viktigt inslag i de allra flesta verksamheter och här kan användandet av standarder spela en...

  6. Parametric Analysis of the Exergoeconomic Operation Costs, Environmental and Human Toxicity Indexes of the MF501F3 Gas Turbine

    Directory of Open Access Journals (Sweden)

    Edgar Vicente Torres-González

    2016-08-01

    Full Text Available This work presents an energetic, exergoeconomic, environmental, and toxicity analysis of the simple gas turbine M501F3 based on a parametric analysis of energetic (thermal efficiency, fuel and air flow rates, and specific work output, exergoeconomic (exergetic efficiency and exergoeconomic operation costs, environmental (global warming, smog formation, acid rain indexes, and human toxicity indexes, by taking the compressor pressure ratio and the turbine inlet temperature as the operating parameters. The aim of this paper is to provide an integral, systematic, and powerful diagnostic tool to establish possible operation and maintenance actions to improve the gas turbine’s exergoeconomic, environmental, and human toxicity indexes. Despite the continuous changes in the price of natural gas, the compressor, combustion chamber, and turbine always contribute 18.96%, 53.02%, and 28%, respectively, to the gas turbine’s exergoeconomic operation costs. The application of this methodology can be extended to other simple gas turbines using the pressure drops and isentropic efficiencies, among others, as the degradation parameters, as well as to other energetic systems, without loss of generality.

  7. F2-layer parameters long-term trends at the Argentine Islands and Port Stanley stations

    Directory of Open Access Journals (Sweden)

    A. D. Danilov

    2001-03-01

    Full Text Available The ionospheric sounding data at two southern hemisphere stations, the Argentine Islands and Port Stanley, are analyzed using a method previously developed by the authors. Negative trends of the critical frequency foF2 are found for both stations. The magnitudes of the trends are close to those at the corresponding (close geomagnetic latitude stations of the northern hemisphere, as considered previously by the authors. The values of the F2 layer height hmF2 absolute trends ΔhmF2 are considered. The effect of ΔhmF2 dependence on hmF2 found by Jarvis et al. (1998 is reproduced. A concept is considered that long-term changes of the geomagnetic activity may be an important (if not the only cause of all the trends of foF2 and hmF2 derived by several groups of authors. The dependence of both parameters on the geomagnetic index Ap corresponds to a smooth scheme of the ionospheric storm physics and morphology; thus, a principal cause of the foF2 and hmF2 geomagnetic trends is most probably a trend found in several publications in the number and intensity of ionospheric storms.Key words. Ionosphere (ionosphere-atmosphere interaction; ionospheric disturbances

  8. New wrought Ni-based superalloys with low thermal expansion for 700C steam turbines

    Energy Technology Data Exchange (ETDEWEB)

    Yamamoto, R.; Kadoya, Y. [Takasago Research and Development Center, Mitsubishi Heavy Industries, Ltd., Takasago, Hyogo (Japan); Kawai, H.; Magoshi, R. [Takasago Machinery Works, Mitsubishi Heavy Industries, Ltd., Takasago, Hyogo (Japan); Noda, T.; Hamano, S.; Ueta, S.; Isobe, S. [Research and Development Lab., Daido Steel Co., Ltd., Minamiku, Nagoya (Japan)

    2002-07-01

    Advanced 700C class steam turbines require austenitic alloys to replace conventional ferritic 12Cr steels, which lose creep strength and oxidation resistance above 650C. The austenitic alloys, however, possess a higher thermal expansion coefficient than ferritic 12Cr steels. Therefore, Ni-based superalloys were tailored to reduce their coefficients to the level of 12Cr steels. A regression analysis of commercial superalloys proves that Ti, Mo and Al decrease the coefficient quantitatively in this order, while Cr increases it so significantly that Cr should be limited to 12wt% to secure oxidation resistance. The newly designed Ni-18Mo-12Cr-1.1Ti-0.9Al alloy is strengthened by gamma-prime [Ni{sub 3}(Al,Ti)] and also Laves [Ni{sub 2}(Mo,Cr)] phase precipitates. It bears a RT/700C mean expansion coefficient equivalent to that of 12Cr steels and far lower than that of low-alloyed heat resistant steels. It surpasses a current turbine alloy, Refractaloy 26, in tensile strength at RT to 700C and SCC life in 330C deaerated pure water. Its creep rupture life at 700C is equivalent to that of Refractaloy 26. The developed alloy will be suitable for fasteners and/or blades in steam turbines at present and future USC power plants. (orig.)

  9. Johnston Island, Pacific Island. Revised Uniform Summary of Surface Weather Observations (RUSSWO). Parts A-F.

    Science.gov (United States)

    1973-06-07

    25 Ft 5 Far;5toj Located on top of OPS/veather Selayn ML144B 40 Ft Jeb 56 5ration. 6 yar 56to Located on top of Base Operation Same Same Same ;Feb 57...8217 128 72.2 2, 28 Jz .J f’ 72..i 7.2 11 14000 td ~ 7 . 9 7?..9 7 , .9 7 2.9 7e1.9 󈨌 .9 72.9 12 .9 72.9 72.9 72.9 72.9 72.9 72.12000 i1i.21 7.( , 567 75

  10. 78 FR 63017 - Exhaust Emissions Standards for New Aircraft Gas Turbine Engines and Identification Plate for...

    Science.gov (United States)

    2013-10-23

    ... Aircraft Gas Turbine Engines and Identification Plate for Aircraft Engines AGENCY: Federal Aviation... adopting the gas turbine engine test procedures of the International Civil Aviation Organization (ICAO... regulations, the FAA proposed and the EPA accepted the idea that referring to these engines as exceptions to...

  11. Understanding IEC standard wind turbine models using SimPowerSystems

    DEFF Research Database (Denmark)

    Das, Kaushik; Hansen, Anca Daniela; Sørensen, Poul Ejnar

    2016-01-01

    This article describes and exemplifies the IEC 61400-27 generic wind turbine models through an interactive multimedia learning environment - Matlab SimPowerSystems. The article aims help engineers with different backgrounds to get a better understanding of wind turbine dynamics and control...... by easily conducting different study simulations in the SimPowerSystems platform ....

  12. Deformation microstructure and orientation of F.C.C. crystals

    DEFF Research Database (Denmark)

    Liu, Q.; Hansen, N.

    1995-01-01

    that dependent on the crystallographic orientation of the crystal the subdividing boundaries may be nearly parallel to slip planes or they may have a non-crystallographic orientation. This difference is discussed on the basis of an analysis of potential slip planes identified by a Schmid factor analysis.......The effect of crystallographic orientation on the microstructural evolution in f.c.c. metals with medium to high stacking fault energy is analyzed. This analysis is based on a literature review of the behaviour of single crystals and polycrystals supplemented with an experimental study of cold......-rolled pure aluminium. It is generally observed that all crystallites subdivide during deformation into cell blocks and cells bounded by rotation dislocation boundaries. In general the boundaries have a macroscopic orientation with respect to the geometry of the specimen. A crystallographic analysis shows...

  13. NRL Radar Division C++ Coding Standard

    Science.gov (United States)

    2016-12-05

    are: • Free of common types of errors • Maintainable by different programmers • Portable to other operating systems • Easy to read and understand...const-declared parameters is that the compiler will actually give you an error if you modify such a parameter by mistake , thus helping you to avoid...The coding standard provides tools aimed at helping C++ programmers develop programs that are free of common types of errors , maintainable by

  14. Development of gas temperature probes for 1700 degrees C hydrogen-combustion turbine combustors; 1700 degrees C suiso nensho turbine yo nenshokino gas ondo keisoku probe no kaihatsu

    Energy Technology Data Exchange (ETDEWEB)

    Hisamatsu, T. [Central Research Inst. of Electric Power Industry, Tokyo (Japan); Nishida, H.; Kasai, Y.; Fukahori, O. [Mitsubishi Heavy Industries, Ltd., Tokyo (Japan); Murayama, M. [Ishikawajima-Harima Heavy Industries Co. Ltd., Tokyo (Japan); Dodo, S. [Hitachi, Ltd., Tokyo (Japan)

    2000-05-20

    In the development of the Hydrogen-oxygen combustor for 1700 degrees C Hydrogen-combustion turbines, it is important to measure gas temperature distribution at combustor outlet where local temperatures are estimated over 1800 degrees C in order to evaluate the performance of combustors. Multi point gas temperature probes consisting of Pt/Rh 40% Pt/Rh 20% thermocouples are developed to measure gas temperature distribution in the combustion tests of the Hydrogen-Oxygen combustors. Two types of probes no cooled and water-cooled, are designed and tested on the high pressure combustion tests. The test results demonstrate that the water-cooled type probes enable us to measure local gas temperatures up to 1850 degrees C in 2.5 Mpa, 130 m/s steam flow, and are applicable to the combustion tests of the combustor. (author)

  15. Multi-scale thermodynamic analysis method for 2D SiC/SiC composite turbine guide vanes

    Directory of Open Access Journals (Sweden)

    Xin LIU

    2018-01-01

    Full Text Available Ceramic Matrix Composite (CMC turbine guide vanes possess multi-scale stress and strain with inhomogeneity at the microscopic scale. Given that the macroscopic distribution cannot reflect the microscopic stress fluctuation, the macroscopic method fails to meet the requirements of stress and strain analysis of CMC turbine guide vanes. Furthermore, the complete thermodynamic properties of 2D woven SiC/SiC-CMC cannot be obtained through experimentation. Accordingly, a method to calculate the thermodynamic properties of CMC and analyze multi-scale stress and strain of the turbine guide vanes should be established. In this study, the multi-scale thermodynamic analysis is investigated. The thermodynamic properties of Chemical Vapor Infiltration (CVI processed SiC/SiC-CMC are predicted by a Representative Volume Element (RVE model with porosity, leading to the result that the relative error between the calculated in-plane tensile modulus and the experimental value is 4.2%. The macroscopic response of a guide vane under given conditions is predicted. The relative error between the predicted strain on the trailing edge and the experimental value is 9.7%. The calculation of the stress distribution of micro-scale RVE shows that the maximum value of microscopic stress, which is located in the interlayer matrix, is more than 1.5 times that of macroscopic stress in the same direction and the microscopic stress distribution of the interlayer matrix is related to the pore distribution of the composite.

  16. New Ionosonde Observations of Mid Latitude Spread-F at Wallops Island

    Science.gov (United States)

    Bullett, T.

    2008-12-01

    A new generation digital ionosonde, a Vertical Incidence Pulsed Ionospheric Radar (VIPIR) was installed at the NASA Wallops Island Flight Facility in Virginia and saw first operation in 2007. The VIPIR features dramatic improvements in ionosonde and radar system design, including multiple phase-coherent, fully digital receivers, improved antenna designs, and higher data resolution. This produces markedly improved ionograms. From the mid 1980's through today, NASA Wallops hosts a first generation digital ionosonde, a US Air Force Digital Ionospheric Sounding System or Digisonde 256. Phase coherent digital sampling of analog receiver output, digital data storage and automated real time ionogram scaling allowed spread-F quantification and use of the data for launch decisions. In the 1970's and early 1980's an analog ionosonde, at Wallops recorded data on photographic film. Hourly characteristics were later scaled by hand, with spread-F being qualitatively identified. Recently, select periods of film ionograms have been digitized by NOAA/NGDC and are available in electronic format. This presentation compares spread-F observations made with three generations of ionospheric sounding equipment operated at the NASA Wallops Island Flight Facility. Comparison of ionogram data from both VIPIR and Digisonde ionosondes during several different events reveals newly observed mid-latitude spread- F features.

  17. Reaction of Cl atoms with C6F13CH2OH, C6F13CHO, and C3F7CHO.

    Science.gov (United States)

    Solignac, G; Mellouki, A; Le Bras, G; Barnes, I; Benter, Th

    2006-04-06

    The Cl atom initiated oxidation of C(6)F(13)CH(2)OH, C(6)F(13)CHO, and C(3)F(7)CHO was investigated at 298 K and 1000 mbar pressure of air in a photoreactor using in situ Fourier transform infrared (FTIR) analysis. The rate coefficient for the reaction Cl + C(6)F(13)CH(2)OH (reaction 2) was measured using a relative method: k(2) = (6.5 +/- 0.8) x 10(-13) cm(3) molecule(-1) s(-1). C(6)F(13)CHO was detected as the major primary product, while CO and CF(2)O were found to be the major secondary products. A fitting procedure applied to the concentration-time profiles of C(6)F(13)CHO provided a production yield of (1.0 +/- 0.2) for this aldehyde in reaction 2, and the rate coefficient for the reaction Cl + C(6)F(13)CHO (reaction 4) was k(4) = (2.8 +/- 0.7) x 10(-12) cm(3) molecule(-1) s(-1). A high CO yield observed in the oxidation of C(6)F(13)CH(2)OH, (52 +/- 1)%, is attributed to the Cl atom initiated oxidation of C(6)F(13)CHO. High CO yields, (61 +/- 2)% and (85 +/- 5)%, were also measured in the Cl atom initiated oxidation of C(3)F(7)CHO in air and nitrogen, respectively. These high CO yields suggest the occurrence of a decomposition reaction of the perfluoroacyl, C(6)F(13)CO, and C(3)F(7)CO radicals to form CO which will compete with the combination reaction of these radicals with oxygen to form perfluoroacyl peroxy radicals in the presence of air. The latter radicals C(n)F(2)(n)(+1)CO(O)(2) (n = 6-12), through their reaction with HO(2) radicals, are currently considered as a possible source of persistent perfluorocarboxylic acids which have been detected in the environment. The consequences of the present results would be a reduction of the strength of this potential source of carboxylic acids in the atmosphere.

  18. Stationary Combustion Turbines: National Emission Standards for Hazardous Air Pollutants (NESHAP)

    Science.gov (United States)

    Learn about the NESHAP for stationary combustion turbines by reading the rule history, the rule summary, additional resources, docket folder documents, the economic impact analysis, fact sheet and more

  19. Stationary gas turbines of all performance classes in a flexible power supply operation; Stationaere Gasturbinen. Gasturbinen aller Leistungsklassen im flexiblen Netzbetrieb

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2012-07-01

    Within the 8th VDI conference from 20th to 21st November, 2012, at the Electoral Palace Mainz (Mainz, Federal Republic of Germany), the following lectures were held: (1) Introduction of the twin-shaft industrial gas turbine SGT-300 (C. Engelbert); (2) The new 6 MW gas turbine for the power generation (Michael Blaswich); (3) Successful increase of the breakeven performance of the SGT5-2000E based on the Si3D blading (S. Kliesch); (4) Advanced Condition Monitoring at E.ON (T. Burridge-Oakland); (5) Experiences from 10 years of monitoring at gas turbine power plants (D. Therkon); (6) Operating experience with GE's Intercooled LMS100 (B. Mehmetli); (7) First long-term experience with the operational flexibility of the SGT5-8000H (C. Scholz); (8) Plant concept and operational concept with small gas turbines for the heat production and power generation meeting the demands in line with market conditions (D. Seibt); (9) Operational experiences with remote diagnostic services in the power range up to 25 MW (H. Berghaus); (10) European regulations having an influence on design and operation of gas turbines - An overview (M. Zelinger); (11) Future concepts for fuel flexibility - Experience with hydrogen-based fuels (R. Lachner); (12) Requirements from functional safety to gas turbines - Importance and benefit for gas turbine development (G. Weber); (13) Standard for the procurement of gas turbines: ISO 19859 Gas turbine applications - requirements for power generation (I. Rattmann); (14) Future projects for fuel flexibility in the test phase: Natural gas / hydrogen co-firing (G. Fruechtel); (15) Measures for the reduction of emissions at Siemens V64.3 gas turbines (K. Jordan); (16) Flexible operation of the SGT5-4000F by fuel transfers in a wide load range (J. Meisl); (17) Technical features of the GT26 gas turbine to improve the flexibility of the combined cycle system KA26 (W. Reiter).

  20. Braun, Wernher von (1912-77)

    Science.gov (United States)

    Murdin, P.

    2000-11-01

    Rocket scientist, born in Wirsitz, Germany, enthusiast of space travel from an early age, designer of the V-2 rocket used during the second World War. With 120 associates from Peenemunde, went to the United States and directed firings of captured V-2 rockets at White Sands Missile Range in New Mexico, following which he used a Jupiter-C (Juno I) to put America's first satellite, Explorer 1, into ...

  1. Stereoselective Synthesis of the C1-C9 and C11-C25 Fragments of Amphidinolides C, C2, C3, and F.

    Science.gov (United States)

    Akwaboah, Daniel C; Wu, Dimao; Forsyth, Craig J

    2017-03-03

    An efficient synthesis of the C1-C9 and the C11-C25 fragments of amphidinolides C, C2, C3, and F from a common intermediate is reported. The construction of the C1-C9 fragment involves an intramolecular hetero-Michael cyclization to form the 3,5-disubstituted trans-tetrahydrofuran moiety. The approach to prepare the C11-C25 fragment utilizes a highly stereoselective aerobic cobalt-catalyzed alkenol cyclization and a chelated Mukaiyama aldol reaction to form the C13-C14 bond and to concomitantly install the C13 hydroxyl group.

  2. Aircraft Turbine Engine Monitoring Experience: Implications for the F100 Engine Diagnostic System Program

    Science.gov (United States)

    1979-04-01

    T-38IJ85 FLEET RETROFIT NOT ( EHMS )JULY 76 - MAY 77 RECOMMENDED (CONTROL GROUP) MALFUNCTION DETECTION ANALYSIS C-5AlTF39 CONTINUOUS RECORDINGS...report we have selected two case studies as illustrative examples: the EHMS on the T-38 because it is the U.S. AF system that most closely resembles the...will be discussed below. THE T-38 EHMS CASE STUDY The T-38 EHMS is the Air Force system most similar to the F100 EDS. It emphasizes improved day-to-day

  3. Strategies for the implementation of wind turbines in Fernando de Noronha island; Estrategias de implantacao de turbinas eolicas na ilha de Fernando de Noronha

    Energy Technology Data Exchange (ETDEWEB)

    Rohatgi, J.; Feitosa, E.; Correa, M. [Pernambuco Univ., Recife, PE (Brazil). Centro de Pesquisa de Energia Eolica

    1990-12-31

    The island of Fernando de Noronha is one of the best sites in Brazil to make use of winds for the electricity generation. Three principal factors contribute to this fact: the high wind potential; the fact that all be electricity generation on the island is done by diesel generator; the pollution of atmosphere due to the burning of diesel oil. At the moment the unit price of energy is very high an due to social reasons it is subsidized. This paper presents the strategies to implement the first wind turbine of medium size of 75 kW (17 m in diameter) so as to contribute effectively to the reduction of diesel oil consumption. 7 refs., 4 figs., 2 tabs

  4. , 26-ESKADER R.F.C.

    African Journals Online (AJOL)

    om teen die huidige besoldiging by 'n oorsese eskader aan te sluit en of lte. J. Clisdal, E. F. Driver, H. V. Batten, A. R. Earle, W. W. Carey Thomas, John ;:n. Power bereid sal wees om teen Imperiale soldy dieselfde te doen. Verder is gevra hoeveel onderoffisiere en manskappe in die Unie ooreenkomstig die Imperi-.

  5. Oscar Braun: un referente ineludible para interpretar el presente nacional

    OpenAIRE

    Azpiazu, Daniel; Schorr, Martín; Instituto Interdisciplinario de Economía Política de Buenos Aires

    2008-01-01

    Se brinda un extracto de una conferencia que el economista Oscar Braun dictó en noviembre de 1973 en la Facultad de Filosofía y Letras de la Universidad de Buenos Aires. El texto completo fue publicado en 1974 por la editorial El Coloquio bajo el título El plan económico del gobierno popular. Se trata de una serie de reflexiones que a pesar de haber sido escritas en otro momento histórico, arrojan numerosas claves interpretativas de la particular coyuntura económica y socio-política de la ...

  6. Application of CRO-EOL expert system for selecting the optimal wind turbine generator system as part of a combined electric energy system of an island

    Energy Technology Data Exchange (ETDEWEB)

    Klarin, Branko; Pilic-Rabadan, Ljiljana; Milas, Zoran [University of Split, Faculty of Electrical Engineering, Mechanical Engineering and Naval Architecture, Split (Croatia)

    1996-12-31

    This work deals with the problems in selecting the units of a wind turbine generator system which are to be built into the wind farms for operation in combination with classical sources of electric energy. Using the example of a Mediterranean island the course of procedure is presented and the results make part of the study on determination of the island development strategy, with tourism being its principal economic branch. The selection of optimal units of the wind turbine generator system should be based on a set of influencing factors. The selection is carried out by means of the expert system mechanism, taking into account the requirements for environmental protection and technical and economic parameters. It can be concluded that the obtained wind generator units are optimal with respect to the given criteria. The production of electric energy obtained by simulating the operation of a wind energy plant is feasible in practice at a price per kWh competitive with classical energy sources. (Author)

  7. Ceramic stationary gas turbine

    Energy Technology Data Exchange (ETDEWEB)

    Roode, M. van [Solar Turbines Inc., San Diego, CA (United States)

    1995-10-01

    The performance of current industrial gas turbines is limited by the temperature and strength capabilities of the metallic structural materials in the engine hot section. Because of their superior high-temperature strength and durability, ceramics can be used as structural materials for hot section components (blades, nozzles, combustor liners) in innovative designs at increased turbine firing temperatures. The benefits include the ability to increase the turbine inlet temperature (TIT) to about 1200{degrees}C ({approx}2200{degrees}F) or more with uncooled ceramics. It has been projected that fully optimized stationary gas turbines would have a {approx}20 percent gain in thermal efficiency and {approx}40 percent gain in output power in simple cycle compared to all metal-engines with air-cooled components. Annual fuel savings in cogeneration in the U.S. would be on the order of 0.2 Quad by 2010. Emissions reductions to under 10 ppmv NO{sub x} are also forecast. This paper describes the progress on a three-phase, 6-year program sponsored by the U.S. Department of Energy, Office of Industrial Technologies, to achieve significant performance improvements and emissions reductions in stationary gas turbines by replacing metallic hot section components with ceramic parts. Progress is being reported for the period September 1, 1994, through September 30, 1995.

  8. Structure of turbulent velocity field in the discharge stream from a standard Rushton turbine impeller

    Czech Academy of Sciences Publication Activity Database

    Kysela, Bohuš; Konfršt, Jiří; Chára, Zdeněk; Fořt, I.

    2017-01-01

    Roč. 23, č. 2 (2017), s. 151-160 ISSN 1451-9372 R&D Projects: GA ČR GA16-20175S Institutional support: RVO:67985874 Keywords : rushton turbine * LDA * discharge stream * agitated vessel Subject RIV: BK - Fluid Dynamics Impact factor: 0.664, year: 2016

  9. H gas turbine combined cycle

    Energy Technology Data Exchange (ETDEWEB)

    Corman, J. [General Electric Co., Schenectady, NY (United States)

    1995-10-01

    A major step has been taken in the development of the Next Power Generation System - {open_quotes}H{close_quotes} Technology Combined Cycle. This new gas turbine combined-cycle system increases thermal performance to the 60% level by increasing gas turbine operating temperature to 1430 C (2600 F) at a pressure ratio of 23 to 1. Although this represents a significant increase in operating temperature for the gas turbine, the potential for single digit NOx levels (based upon 15% O{sub 2}, in the exhaust) has been retained. The combined effect of performance increase and environmental control is achieved by an innovative closed loop steam cooling system which tightly integrates the gas turbine and steam turbine cycles. The {open_quotes}H{close_quotes} Gas Turbine Combined Cycle System meets the goals and objectives of the DOE Advanced Turbine System Program. The development and demonstration of this new system is being carried out as part of the Industrial/Government cooperative agreement under the ATS Program. This program will achieve first commercial operation of this new system before the end of the century.

  10. Use of Braun-Blanquet for the assessment of veld condition and ...

    African Journals Online (AJOL)

    Braun-Blanquet vegetation surveys are easier and quicker to undertake than point surveys. This paper reports on assessment of veld condition and calculation of grazing capacity of five plant communities of the Ea land type of the northeastern Orange Free State using Braun-Blanquet data. Veld condition scores were ...

  11. Generation and Standardized, Systemic Phenotypic Analysis of Pou3f3L423P Mutant Mice.

    Science.gov (United States)

    Kumar, Sudhir; Rathkolb, Birgit; Kemter, Elisabeth; Sabrautzki, Sibylle; Michel, Dian; Adler, Thure; Becker, Lore; Beckers, Johannes; Busch, Dirk H; Garrett, Lillian; Hans, Wolfgang; Hölter, Sabine M; Horsch, Marion; Klingenspor, Martin; Klopstock, Thomas; Rácz, Ildikó; Rozman, Jan; Vargas Panesso, Ingrid Liliana; Vernaleken, Alexandra; Zimmer, Andreas; Fuchs, Helmut; Gailus-Durner, Valérie; Hrabě de Angelis, Martin; Wolf, Eckhard; Aigner, Bernhard

    2016-01-01

    Increased levels of blood plasma urea were used as phenotypic parameter for establishing novel mouse models for kidney diseases on the genetic background of C3H inbred mice in the phenotype-driven Munich ENU mouse mutagenesis project. The phenotypically recessive mutant line HST011 was established and further analyzed. The causative mutation was detected in the POU domain, class 3 transcription factor 3 (Pou3f3) gene, which leads to the amino acid exchange Pou3f3L423P thereby affecting the conserved homeobox domain of the protein. Pou3f3 homozygous knockout mice are published and show perinatal death. Line Pou3f3L423P is a viable mouse model harboring a homozygous Pou3f3 mutation. Standardized, systemic phenotypic analysis of homozygous mutants was carried out in the German Mouse Clinic. Main phenotypic changes were low body weight and a state of low energy stores, kidney dysfunction and secondary effects thereof including low bone mineralization, multiple behavioral and neurological defects including locomotor, vestibular, auditory and nociceptive impairments, as well as multiple subtle changes in immunological parameters. Genome-wide transcriptome profiling analysis of kidney and brain of Pou3f3L423P homozygous mutants identified significantly regulated genes as compared to wild-type controls.

  12. Generation and Standardized, Systemic Phenotypic Analysis of Pou3f3L423P Mutant Mice.

    Directory of Open Access Journals (Sweden)

    Sudhir Kumar

    Full Text Available Increased levels of blood plasma urea were used as phenotypic parameter for establishing novel mouse models for kidney diseases on the genetic background of C3H inbred mice in the phenotype-driven Munich ENU mouse mutagenesis project. The phenotypically recessive mutant line HST011 was established and further analyzed. The causative mutation was detected in the POU domain, class 3 transcription factor 3 (Pou3f3 gene, which leads to the amino acid exchange Pou3f3L423P thereby affecting the conserved homeobox domain of the protein. Pou3f3 homozygous knockout mice are published and show perinatal death. Line Pou3f3L423P is a viable mouse model harboring a homozygous Pou3f3 mutation. Standardized, systemic phenotypic analysis of homozygous mutants was carried out in the German Mouse Clinic. Main phenotypic changes were low body weight and a state of low energy stores, kidney dysfunction and secondary effects thereof including low bone mineralization, multiple behavioral and neurological defects including locomotor, vestibular, auditory and nociceptive impairments, as well as multiple subtle changes in immunological parameters. Genome-wide transcriptome profiling analysis of kidney and brain of Pou3f3L423P homozygous mutants identified significantly regulated genes as compared to wild-type controls.

  13. 16 CFR Appendix F1 to Part 305 - Standard Clothes Washers

    Science.gov (United States)

    2010-01-01

    ... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Standard Clothes Washers F1 Appendix F1 to... Appendix F1 to Part 305—Standard Clothes Washers Range Information “Standard” includes all household clothes washers with a tub capacity of 1.6 cu. ft. or more. Capacity Range of Estimated Annual Operating...

  14. Blood recipient notification for hepatitis C in Prince Edward Island.

    Science.gov (United States)

    Van Til, L D; Sweet, L E

    2000-01-25

    Two of the major risk factors for hepatitis C are injection drug use and receipt of blood or blood products. Many patients are unaware that they have received transfusions. In 1998 Prince Edward Island conducted a province-wide look-back notification program to notify patients who had received transfusions in PEI between Jan. 1, 1984, and June 1, 1990. The authors present the results of the notification program. A registry for recipients of blood and blood products was created from the province's Red Cross blood bank records. The registry data were linked with Vital Statistics data to determine death status and with Health Registration data to determine residence status of recipients (in PEI or moved out of province). All identified recipients with a current PEI mailing address were sent a letter recommending hepatitis C virus (HCV) testing. Laboratory records were checked to determine HCV test results. The registry contained data for 6086 recipients of blood or blood products during the look-back period; 51.1% (3109/6086) had died by the time of notification. Of the remainder, 18.4% (549/2977) were not directly notified because they had moved out of province, had refused delivery of the notification letter or had died recently, or because identifying information was missing from the blood bank records. Of the recipients who were notified 80.4% (1953/2428) underwent testing, and 2.2% (43/1953) were found to be HCV positive. Most of these (58.1% [25/43]) had undergone testing before notification. The HCV positivity rate differed significantly between recipients tested before notification and those tested after notification (9.9% v. 1.1%, p < 0.001). HCV-positive recipients were more likely than other notified recipients to have had multiple transfusions (39.5% v. 9.5%, p < 0.001). Before notification 4.1% of PEI recipients had undergone HCV testing. After notification 91.2% of PEI recipients were identified as tested, dead or moved out of province. The notification

  15. 26 CFR 5c.168(f)(8)-2 - Election to characterize transaction as a section 168(f)(8) lease.

    Science.gov (United States)

    2010-04-01

    ... section 168(f)(8) lease. 5c.168(f)(8)-2 Section 5c.168(f)(8)-2 Internal Revenue INTERNAL REVENUE SERVICE... ECONOMIC RECOVERY TAX ACT OF 1981 § 5c.168(f)(8)-2 Election to characterize transaction as a section 168(f... property was first placed in service, as defined in § 5c.168(f)(8)-6(b)(2)(i) (or prior to November 14...

  16. Design of steam turbine for 593[degree]C reheat temperature. Sainetsu joki ondo 593[degree]C turbine no keikaku

    Energy Technology Data Exchange (ETDEWEB)

    Matsukuma, M.; Fujikawa, T.; Takayanagi, K. (Mitsubishi Heavy Industries, Ltd., Tokyo (Japan))

    1993-02-15

    Following the successful completion of the first stage operation with main/reheat steam temperature of 593/593 centigrade for the Wakamatsu high temperature 50MW turbine of Electric Power Development Co., the large high temperature steam turbines for the hot reheat temperature of 593 centigrade are currently being realized for the first time in Japan. Namely, the Hekinan No.3 unit of Chubu Electric Power Company is being constructed, which has 246kg/cm[sup 2], 538/593 centigrade 700MW turbine, and the design of the Nanao-Ohta No.1 unit of Hokuriku Electric Power Company is in progress, which has 246kg/cm[sup 2], 566/593 centigrade 500MW turbine. The present paper describes the results of demonstration tests of the Wakamatsu high temperature turbine conducted for three years and three months from 1986 to 1990, and introduces outline of development, features in the design, and problems to be considered of these high temperature steam turbines designed for the 593 centigrade hot reheat steam temperature. 15 figs., 2 tabs.

  17. Molecular tuning of the closed shell C-H···F-C hydrogen bond.

    Science.gov (United States)

    Lu, Norman; Ley, Rebecca M; Cotton, Charles E; Chung, Wei-Cheng; Francisco, Joseph S; Negishi, Ei-ichi

    2013-08-29

    The existence of the rare six-membered and intramolecular C-H···F-C hydrogen-bond has been experimentally proven in the gas phase and in the solid state recently. However, the effect of the substituents on this C-H···F-C hydrogen-bond system has never been reported. In view of the importance of this type of C-H···F-C H-bonding whose weak interaction has been found critical in nanotechnology and biological systems, the nine functional groups composed of electron donating and electron withdrawing groups are inserted into this C-H···F-C interaction to study the group effect on the hydrogen bonding. Group effects on this C-H···F-C H-bonding system have been found, and their effects on the H-bonding system have been found to be tunable.

  18. SMART POWER TURBINE

    Energy Technology Data Exchange (ETDEWEB)

    Nirm V. Nirmalan

    2003-11-01

    remarkably high, that is a 1-2.5% change in ratio for an 11.1 C (20 F) change in temperature at flame temperatures between 1482.2 C (2700 F) and 1760 C (3200 F). Sensor ratio calibration was performed using flame temperatures determined by calculations using the amount of unburned oxygen in the exhaust and by the fuel/air ratio of the combustible gas mixture. The agreement between the results of these two methods was excellent. The sensor methods characterized are simple and viable. Experiments are underway to validate the GE Flame Temperature Sensor as a practical tool for use with multiburner gas turbine combustors. The lower heating value (LHV) Fuel Quality Sensor consists of a catalytic film deposited on the surface of a microhotplate. This micromachined design has low heat capacity and thermal conductivity, making it ideal for heating catalysts placed on its surface. Several methods of catalyst deposition were investigated, including micropen deposition and other proprietary methods, which permit precise and repeatable placement of the materials. The use of catalysts on the LHV sensor expands the limits of flammability (LoF) of combustion fuels as compared with conventional flames; an unoptimized LoF of 1-32% for natural gas (NG) in air was demonstrated with the microcombustor, whereas conventionally 4 to 16% is observed. The primary goal of this work was to measure the LHV of NG fuels. The secondary goal was to determine the relative quantities of the various components of NG mixes. This determination was made successfully by using an array of different catalysts operating at different temperatures. The combustion parameters for methane were shown to be dependent on whether Pt or Pd catalysts were used. In this project, significant effort was expended on making the LHV platform more robust by the addition of high-temperature stable materials, such as tantalum, and the use of passivation overcoats to protect the resistive heater/sensor materials from degradation in the

  19. Turbine Research Program Cold Weather Turbine Project: Period of Performance May 27, 1999 -- March 31, 2004

    Energy Technology Data Exchange (ETDEWEB)

    Lynch, J.; Bywaters, G.; Costin, D.; Hoskins, S.; Mattila, P.; Stowell, J.

    2004-08-01

    Northern Power Systems completed the Cold Weather Turbine (CWT) project, which was funded by the National Renewable Energy Laboratory (NREL), under subcontract XAT-9-29200-01. The project's primary goal is to develop a 100-kW wind turbine suited for deployment in remote villages in cold regions. The contract required testing and certification of the turbine to the International Electrotechnical Commission (IEC) 61400-1 international standard through Underwriters Laboratories (UL). The contract also required Northern Power Systems to study design considerations for operation in extreme cold (-80F at the South Pole, for example). The design was based on the successful proof of concept (POC) turbine (developed under NREL and NASA contracts), considered the prototype turbine that would be refined and manufactured to serve villages in cold regions around the world.

  20. 26 CFR 5c.168(f)(8)-8 - Loss of section 168(f)(8) protection; recapture.

    Science.gov (United States)

    2010-04-01

    .... 5c.168(f)(8)-8 Section 5c.168(f)(8)-8 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE... TAX ACT OF 1981 § 5c.168(f)(8)-8 Loss of section 168(f)(8) protection; recapture. (a) In general. Upon... its income tax return as required in § 5c.168(f) (8)-2 (a)(3)(iii). (3) The lessee (or any transferee...

  1. Syntheses and Characterization of W(NC6F5)F5- and W2(NC6F5)2F9- Salts and Computational Studies of the W(NR)F5- (R = H, F, CH3, CF3, C6H5, C6F5) and W2(NC6F5)2F9- Anions.

    Science.gov (United States)

    Turnbull, Douglas; Wetmore, Stacey D; Gerken, Michael

    2017-10-16

    Convenient preparative routes to fluorido[(pentafluorophenyl)imido]tungstate(VI) salts have been developed. The reaction of WF6·NC5H5 or [N(CH3)4][WF7] with C6F5NH2 results in quantitative formation of the C5H5NH+ or N(CH3)4+ salt of the W(NC6F5)F5- anion, respectively. The dissolution of [C5H5NH][W(NC6F5)F5] in anhydrous HF results in the formation of [C5H5NH][W2(NC6F5)2F9]. These salts have been comprehensively characterized in the solid state by X-ray crystallography and Raman spectroscopy and in solution by 19F and 1H NMR spectroscopy. The crystal structures of the W(NC6F5)F5- salts reveal conformational differences in the anions, and the 19F NMR spectra of these salts in CH3CN reveal coupling of the axial fluorido ligand to the 14N nucleus of the imido ligand. In addition, density functional theory (DFT-B3LYP) calculations have been performed on a series of W(NR)F5- anions (R = H, F, CH3, CF3, C6H5, C6F5) and the W2(NC6F5)2F9- anion, including gas-phase geometry optimizations, vibrational frequencies, molecular orbitals, and natural bond orbital (NBO) analyses.

  2. Effects of micro-water on decomposition of the environment-friendly insulating medium C5F10O

    Science.gov (United States)

    Xiao, Song; Li, Yi; Zhang, Xiaoxing; Tian, Shuangshuang; Deng, Zaitao; Tang, Ju

    2017-06-01

    SF6 is widely used in all kinds of high-voltage electrical equipment because of its excellent insulation and arc-extinguishing performance. However, this compound leads to serious greenhouse effect, which harms the environment. Many research institutions are now actively in search of SF6 alternative gas. C5F10O has attracted much attention as an alternative gas with low global warming potential (GWP) and excellent dielectric strength. In this paper, we analyzed the possible decomposition paths of C5F10O under micro-water environment through density functional theory. We also evaluated the ionization parameters and toxicity of the decomposition products. The results show that OH• and H• produced by H2O exhibited a catalytic effect on the decomposition of C5F10O. CF4, C2F6, C3F6, C3F8, C4F10, C5F12, C6F14, C3F7COH, C3F7OH, CF3COH, C3F7H, and CF3OH were produced in the micro-water environment. Based on molecular configuration calculation, the ionization parameters of these products were inferior to perfluorocarbons, such as C3F8, leading to reduced insulation performance of the system. Moreover, CF2O and HF are hazardous to human health and equipment safety. Results will provide a basis for further study of the insulation characteristic of the C5F10O gas mixture under micro-water condition to guide the formulation of their relevant international standards prior to engineering applications.

  3. Effects of micro-water on decomposition of the environment-friendly insulating medium C5F10O

    Directory of Open Access Journals (Sweden)

    Song Xiao

    2017-06-01

    Full Text Available SF6 is widely used in all kinds of high-voltage electrical equipment because of its excellent insulation and arc-extinguishing performance. However, this compound leads to serious greenhouse effect, which harms the environment. Many research institutions are now actively in search of SF6 alternative gas. C5F10O has attracted much attention as an alternative gas with low global warming potential (GWP and excellent dielectric strength. In this paper, we analyzed the possible decomposition paths of C5F10O under micro-water environment through density functional theory. We also evaluated the ionization parameters and toxicity of the decomposition products. The results show that OH• and H• produced by H2O exhibited a catalytic effect on the decomposition of C5F10O. CF4, C2F6, C3F6, C3F8, C4F10, C5F12, C6F14, C3F7COH, C3F7OH, CF3COH, C3F7H, and CF3OH were produced in the micro-water environment. Based on molecular configuration calculation, the ionization parameters of these products were inferior to perfluorocarbons, such as C3F8, leading to reduced insulation performance of the system. Moreover, CF2O and HF are hazardous to human health and equipment safety. Results will provide a basis for further study of the insulation characteristic of the C5F10O gas mixture under micro-water condition to guide the formulation of their relevant international standards prior to engineering applications.

  4. Monofluorinated analogues of polybrominated diphenylethers (F-PBDEs) - standards for analysis. Retention behaviour in gas chromatography

    Energy Technology Data Exchange (ETDEWEB)

    Luthe, G.; Liu, H.; Johansen, J.E. [Chiron Trondheim (Norway); Leonards, P.E.G. [RIVO Ijmuiden (Netherlands)

    2004-09-15

    Polybrominated diphenyl ethers (PBDEs) are globally distributed in the environment. Over the past two decades, they have been used as flame retardants. PBDEs have been found to bioaccumulate. There is a concern about the health effects of PBDE exposure, because of their potential endocrine disrupting properties. PBDEs are structurally similar to polychlorinated biphenyls (PCBs), dibenzodioxines and dibenzofuranes. Therefore, they have to be determined very frequently at the trace level in, e.g. water, food, sediment and soil. The sample preparation and final determination may well lead to systematic and non-systematic (random) errors. It is generally accepted that the accurate determination of micro contaminants in such complex mixtures requires the use of external or, preferably, internal standards (ISs). The benefit of using ISs with physico-chemical properties similar to those of the target compounds, is that both types of errors will be minimized. While preliminary work on monofluorinated polycyclic aromatic hydrocarbons (F-PAHs) as ISs in gas chromatography (GC) was very promising, we recently synthesized a series of monofluorinated polybrominated diphenylethers (F-PBDE). We found that they are a very promising set of internal standards for trace-level analysis of PBDEs and are alternatives to {sup 13}C-labelled analogues. In the present study, we focused attention on the retention behavior of FPBDEs in GC, with the intention to use them as calibration standards for electron impact mass spectrometry (EI-MS) and GC-MS in the negative chemical ionisation mode (ECNI) GC-ECNIMS.

  5. Development of standardized air-blown coal gasifier/gas turbine concepts for future electric power systems

    Energy Technology Data Exchange (ETDEWEB)

    Blough, E.; Russell, W.; Leach, J.W.

    1990-08-01

    Computer models have been developed for evaluating conceptual designs of integrated coal gasification combined cycle power plants. An overall system model was developed for performing thermodynamic cycle analyses, and detailed models were developed for predicting performance characteristics of fixed bed coal gasifiers and hot gas clean up subsystem components. The overall system model performs mass and energy balances and does chemical equilibrium analyses to determine the effects of changes in operating conditions, or to evaluate proposed design changes. An existing plug flow model for fixed bed gasifiers known as the Wen II model was revised and updated. Also, a spread sheet model of zinc ferrite sulfur sorbent regeneration subsystem was developed. Parametric analyses were performed to determine how performance depends on variables in the system design. The work was done to support CRS Sirrine Incorporated in their study of standardized air blown coal gasifier gas turbine concepts.

  6. Synthesis of the C1-C25 southern domain of spirastrellolides B and F.

    Science.gov (United States)

    Sabitha, Gowravaram; Rao, Allu Senkara; Yadav, J S

    2013-11-07

    Synthesis of the C1-C25 ABC spiroketal ring system of spirastrellolides B and F has been executed. The synthetic strategy relied on radical cyclization, HWE olefination, (BDP)CuH conjugate reduction and spiro acetalization reactions.

  7. Passivation of surface-nanostructured f-SiC and porous SiC

    DEFF Research Database (Denmark)

    Ou, Haiyan; Lu, Weifang; Ou, Yiyu

    The further enhancement of photoluminescence from nanostructured fluorescent silicon carbide (f-SiC) and porous SiC by using atomic layer deposited (ALD) Al2O3 is studied in this paper.......The further enhancement of photoluminescence from nanostructured fluorescent silicon carbide (f-SiC) and porous SiC by using atomic layer deposited (ALD) Al2O3 is studied in this paper....

  8. Atmospheric chemistry of C2F5CHO: mechanism of the C2F5C(O)O-2+HO2 reaction

    DEFF Research Database (Denmark)

    Andersen, Mads Peter Sulbæk; Hurley, MD; Wallington, TJ

    2003-01-01

    Smog chamber/FTIR techniques were used to study the gas-phase reaction of C2F5C(O) with HO2 radicals in 100-700 Torr of air, or O-2, diluent at 296 K. The reaction proceeds by two pathways leading to formation of C2F5C(O)OH and O-3 in ayield of 24 +/- 4% and C2F5C(O)O radicals, OH radicals and O-2...... in a yield of 76 +/- 4 The gas phase reaction of CnF2n+1C(O)O-2 with HO2 radicals offers a potential explanation for at least part of the observed environmental burden of fluorinated carboxylic acids, CnF2n+1C(O)OH. As part of this work an upper limit for the rate constant of reaction of Cl atorns with C2F5C......(O)OH at 296 K was determined; k(Cl + C2F5C(O)OH)

  9. Wind Plant Models in IEC 61400-27-2 and WECC - latest developments in international standards on wind turbine and wind plant modeling

    DEFF Research Database (Denmark)

    Fortmann, Jens; Miller, Nicholas; Kazachkov, Yuri

    This paper describes the latest developments in the standardization of wind plant and wind plant controller models. As a first step IEC TC88 WG 27 and WECC jointly developed generic wind turbine models which have been published by WECC in 2014 and IEC in 2015 as IEC 61400-27-1, which also include...

  10. Operation of a T63 Turbine Engine Using F24 Contaminated Skydrol 5 Hydraulic Fluid

    Science.gov (United States)

    2016-09-01

    heat generated during hydraulic actuation process. An unexpected leak in these heat exchangers of the hydraulic fluid has the potential to comingle...Liner, First Stage Heat Shield and Fuel Nozzle Prior to Operation of T63 Engine 4 DISTRIBUTION STATEMENT A: Approved for public release...EERF facility. The engine was operated and inspected for leaks for 60 minutes at normal rated power using F-24 fuel. (POSF 12360). The engine

  11. Elaboration of global quality standards for natural and low energy cooling in French tropical island buildings

    CERN Document Server

    Garde, F; Gatina, J C

    2012-01-01

    Electric load profiles of tropical islands in developed countries are characterised by morning, midday and evening peaks arising from all year round high power demand in the commercial and residential sectors, due mostly to air conditioning appliances and bad thermal conception of the building. The work presented in this paper has led to the conception of a global quality standards obtained through optimized bioclimatic urban planning and architectural design, the use of passive cooling architectural components, natural ventilation and energy efficient systems such as solar water heaters. We evaluated, with the aid of an airflow and thermal building simulation software (CODYRUN), the impact of each technical solution on thermal comfort within the building. These technical solutions have been implemented in 280 new pilot dwelling projects through the year 1996.

  12. C++ Coding Standards 101 Rules, Guidelines, and Best Practices

    CERN Document Server

    Sutter, Herb

    2005-01-01

    Consistent, high-quality coding standards improve software quality, reduce time-to-market, promote teamwork, eliminate time wasted on inconsequential matters, and simplify maintenance. Now, two of the world's most respected C++ experts distill the rich collective experience of the global C++ community into a set of coding standards that every developer and development team can understand and use as a basis for their own coding standards.

  13. Cost Effectiveness of ASHRAE Standard 90.1-2013 for the State of Rhode Island

    Energy Technology Data Exchange (ETDEWEB)

    Hart, Philip R. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Athalye, Rahul A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Xie, YuLong [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Zhuge, Jing Wei [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Halverson, Mark A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Loper, Susan A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Rosenberg, Michael I. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Richman, Eric E. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2015-12-01

    Moving to the ASHRAE Standard 90.1-2013 (ASHRAE 2013) edition from Standard 90.1-2010 (ASHRAE 2010) is cost-effective for the State of Rhode Island. The table below shows the state-wide economic impact of upgrading to Standard 90.1-2013 in terms of the annual energy cost savings in dollars per square foot, additional construction cost per square foot required by the upgrade, and life-cycle cost (LCC) per square foot. These results are weighted averages for all building types in all climate zones in the state, based on weightings shown in Table 4. The methodology used for this analysis is consistent with the methodology used in the national cost-effectiveness analysis. Additional results and details on the methodology are presented in the following sections. The report provides analysis of two LCC scenarios: Scenario 1, representing publicly-owned buildings, considers initial costs, energy costs, maintenance costs, and replacement costs—without borrowing or taxes. Scenario 2, representing privately-owned buildings, adds borrowing costs and tax impacts.

  14. C30F12.4 influences oogenesis, fat metabolism, and lifespan in C. elegans.

    Science.gov (United States)

    Wang, Lu; Xu, Fei; Wang, Guishuan; Wang, Xiaorong; Liang, Ajuan; Huang, Hefeng; Sun, Fei

    2016-10-01

    Reproduction, fat metabolism, and longevity are intertwined regulatory axes; recent studies in C. elegans have provided evidence that these processes are directly coupled. However, the mechanisms by which they are coupled and the reproductive signals modulating fat metabolism and lifespan are poorly understood. Here, we find that an oogenesis-enriched gene, c30f12.4, is specifically expressed and located in germ cells and early embryos; when the gene is knocked out, oogenesis is disrupted and brood size is decreased. In addition to the reproductive phenotype, we find that the loss of c30f12.4 alters fat metabolism, resulting in decreased fat storage and smaller lipid droplets. Meanwhile, c30f12.4 mutant worms display a shortened lifespan. Our results highlight an important role for c30f12.4 in regulating reproduction, fat homeostasis, and aging in C. elegans, which helps us to better understand the relationship between these processes.

  15. LHCb: F.E.C. for DAQ networks

    CERN Multimedia

    Floros, G; Neufeld, N

    2014-01-01

    The demand for faster and more reliable networks is growing day by day both in commercial and scientific applications, driving many innovations in network protocols, fiber optics and network-controllers. Operating fast links on relatively inexpensive hardware is a very important challenging aspect of this. One important way to enable this is to provide the network with an existing mechanism of error correction, called Forward Error Correction (F.E.C.). Although error-correcting codes exist for over six decades and F.E.C. is applied in various projects, it is still not widespread in Ethernet networks. F.E.C. introduces a very cost effective way to expand the limits of any network based on micro-controllers synthesized on FPGAs, but it is provided only for specific applications, such as backplane systems. Most of the FPGA and/or IP core vendors either do not provide this feature on their Ethernet implementations or their F.E.C. implementations are based on Ethernet micro-controllers that have a different struct...

  16. Ag/C:F Antibacterial and hydrophobic nanocomposite coatings

    Science.gov (United States)

    Kylián, Ondřej; Kratochvíl, Jiří; Petr, Martin; Kuzminova, Anna; Slavínská, Danka; Biederman, Hynek; Beranová, Jana

    Silver-based nanomaterials that exhibit antibacterial character are intensively studied as they represent promising weapon against multi-drug resistant bacteria. Equally important class of materials represent coatings that have highly water repellent nature. Such materials may be used for fabrication of anti-fogging or self-cleaning surfaces. The aim of this study is to combine both of these valuable material characteristics. Antibacterial and highly hydrophobic Ag/C:F nanocomposite films were fabricated by means of gas aggregation source of Ag nanoparticles and sputter deposition of C:F matrix. The nanocomposite coatings had three-layer structure C:F base layer/Ag nanoparticles/C:F top layer. It is shown that the increasing number of Ag nanoparticles in produced coatings leads not only in enhancement of their antibacterial activity, but also causes substantial increase of their hydrophobicity. Under optimized conditions, the coatings are super-hydrophobic with water contact angle equal to 165∘ and are capable to induce 6-log reduction of bacteria presented in solution within 4h.

  17. Evaluation of the contributions of vitellaria paradoxa C. F. Gaertn ...

    African Journals Online (AJOL)

    Upsurge in population has resulted in pressure on many tree species including Vitellaria paradoxa C.F.Gaertn. and Parkia biglobosa (Jacq.) Benth. These species are highly valued for their socio economic potentials. The study therefore assessed the contribution of V. paradoxa and P. biglobosa to rural livelihood in Oyo ...

  18. The k-ε-fP model applied to double wind turbine wakes using different actuator disk force methods

    DEFF Research Database (Denmark)

    Laan, van der, Paul Maarten; Sørensen, Niels N.; Réthoré, Pierre-Elouan

    2015-01-01

    is employed to estimate the power production of the interacting wind turbines, and the results are compared with two existing methods: a method based on tabulated airfoil data and a method based on the axial induction from 1D momentum theory. The proposed method calculates the correct power, while the other...... two methods overpredict it. The results of the k-ε-fP  eddy viscosity model are also compared with the original k-ε eddy viscosity model and large-eddy simulations. Compared to the large-eddy simulations-predicted velocity and power deficits, the k-ε-fP  is superior to the original k-ε model...

  19. C-CAP Land Cover, Commonwealth of the Northern Mariana Islands (CNMI), Asuncion Island, 2004

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set consists of land derived from high resolution imagery and was analyzed according to the Coastal Change Analysis Program (C-CAP) protocol to determine...

  20. Fabrication of injection molded sintered alpha SiC turbine components

    Science.gov (United States)

    Storm, R. S.; Ohnsorg, R. W.; Frechette, F. J.

    1981-01-01

    Fabrication of a sintered alpha silicon carbide turbine blade by injection molding is described. An extensive process variation matrix was carried out to define the optimum fabrication conditions. Variation of molding parameters had a significant impact on yield. Turbine blades were produced in a reasonable yield which met a rigid quality and dimensional specification. Application of injection molding technology to more complex components such as integral rotors is also described.

  1. Microstructure, creep properties, and rejuvenation of service-exposed alloy 713C turbine blades

    Science.gov (United States)

    Maccagno, T. M.; Koul, A. K.; Immarigeon, J.-P.; Cutler, L.; Allem, R.; L'Espérance, G.

    1990-12-01

    A study was carried out on the microstructure and creep properties of aero engine first-stage turbine blades made from Alloy 713C nickel-base superalloy. Results are reported for new blades, blades in two service-exposed conditions, and service-exposed blades subjected to one of three rejuvenation treatments: a recoating heat treatment, a hot isostatic pressing (HIP) + recoating heat treatment, and a HIP + controlled cooling + recoating heat treatment. The blade microstructure undergoes significant change during service, and this leads to a loss in creep properties exhibited by specimens machined from the blade airfoils. Good correlations were observed between the rupture time and the amount of blade airfoil untwist and between the minimum creep rate and the amount of untwist. The recoating heat treatment and the HIP + controlled cooling + recoating treatment were moderately successful in restoring the microstructure and creep properties of the service-exposed blades. In comparison, the HIP + recoating treatment was very successful in rejuvenating creep properties but only for blades having a chemical composition with a lower propensity to form σ phase. For the blades with an unfavorable composition, σ phase was found to form preferentially near the grain boundaries during creep testing, and this had a detrimental effect on the creep properties. Nonetheless, the degree of rejuvenation for these blades was always at least as good as that obtained through the recoating heat treatment alone.

  2. Seasonal abundance of Culicoides imicola and C. obsoletus in the Balearic islands.

    Science.gov (United States)

    Miranda, M A; Rincón, C; Borràs, D

    2004-01-01

    An outbreak of bluetongue (BT) was declared on the Balearic islands of Spain in September and October 2000. In 2001 and 2002, an intensive survey was conducted on cattle farms in Majorca and Minorca for the principal vectors in the Mediterranean Basin, Culicoides imicola and C. obsoletus. Adult Culicoides were collected once a week between June 2001 and December 2002 using CDC light traps. The results from 348 light-trap collections revealed that, in addition to other species of the genus Culicoides, both C. imicola and C. obsoletus appear to be well established on both Majorca and Minorca. Furthermore, both species showed a different seasonal abundance pattern: peak adult populations of C. obsoletus occurred in July, while those of C. imicola peaked in October. These findings indicate that the principal vector in the outbreak of BT in the Balearic islands in 2000 was probably C. imicola.

  3. NODC Standard Format Marine Toxic Substances and Pollutants (F144) chemical identification codes (NODC Accession 9200273)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This archival information package contains a listing of codes and chemical names that were used in NODC Standard Format Marine Toxic Substances and Pollutants (F144)...

  4. Bildungs(relevante Standards für das Lernen mit Neuen Medien

    Directory of Open Access Journals (Sweden)

    Ulf-Daniel Ehlers

    2009-09-01

    Full Text Available "Standards für E-Learning weisen zunächst lediglich ein Qualitätspotenzial auf, welches dann realisiert werden kann, wenn die Beteiligten über die notwendigen Kompetenzen verfügen." Standards in der Medienpädagogik spielen eine zunehmend wichtigere Rolle in Bildungsorganisationen, da Bildungsprozesse sich immer stärker mediatisieren. Dabei können Standards für den Unterricht über Medien und Standards für den Unterricht mit Medien, und zwar konkret mit Computertechnologie, unterschieden werden. Der vorliegende Beitrag konzentriert sich auf letztere Standards (für den Unterricht mit Medien, oder auch: E-Learning und stellt die Frage: Welche Standards gibt es und wie wirken diese auf den Bildungsprozess – wie bildungsrelevant sind sie? Sog. "Standards im E-Learning" werden vielfach auf das Ziel der Interoperabilität und Wiederverwendbarkeit reduziert. Tatsächlich haben sie aber auch Einfluss auf Bildungsprozesse und -abläufe. Im vorliegenden Beitrag wird argumentiert, dass Standards für E-Learning zunächst lediglich ein Qualitätspotenzial aufweisen, welches dann realisiert werden kann, wenn die Beteiligten über die notwendigen Kompetenzen verfügen. Diese werden im vorliegenden Beitrag als Qualitätskompetenzen beschrieben.

  5. C-CAP Land Cover, Big Island, Hawaii

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set consists of land derived from high resolution imagery and was analyzed according to the Coastal Change Analysis Program (C-CAP) protocol to determine...

  6. 78 FR 63015 - Exhaust Emissions Standards for New Aircraft Gas Turbine Engines and Identification Plate for...

    Science.gov (United States)

    2013-10-23

    ... definition that existed before the final rule and was overlooked. The FAA is issuing this technical amendment... aircraft engines which, in the EPA Administrator's judgment, causes or contributes to air pollution that... the final rule. 2. Sec. 34.1--Definitions In the definition of ``Standard day conditions,'' the value...

  7. 77 FR 76842 - Exhaust Emissions Standards for New Aircraft Gas Turbine Engines and Identification Plate for...

    Science.gov (United States)

    2012-12-31

    ... International Civil Aviation Organization standards, and for the identification and marking requirements for... Docket Number FAA- ] 2012-1333 using any of the following methods: Federal eRulemaking Portal: Go to www.... This convention is consistent with the numeric identifier that the Committee on Aviation Environmental...

  8. Aircraft propulsion and gas turbine engines

    National Research Council Canada - National Science Library

    El-Sayed, Ahmed F

    2008-01-01

    ... . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . xvii xxxi xxxiii xxxv Part I Aero Engines and Gas Turbines . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . C...

  9. Psiloxylon mauritianum (Bouton ex Hook.f.) Baillon (Myrtaceae): A promising traditional medicinal plant from the Mascarene Islands

    Science.gov (United States)

    Mahomoodally, Mohamad Fawzi; Korumtollee, Housna Nazifah; Chady, Zaynab Zaina Banu Khan

    2014-01-01

    Psiloxylon mauritianum (PM) (Bouton ex Hook.f.) Baillon (Myrtaceae) is an evergreen endemic medicinal plant which has shown promising uses in traditional medicine from the Mascarene Islands (Mauritius and Réunion Islands). Folk use of this endemic plant in Mauritius and Réunion Islands has been geared toward the treatment and management of amenorrhea, dysentery and Type II diabetes mellitus. Recent findings from in vitro studies have led to the discovery of two potent acids namely corosolic acid and asiatic acid which have been shown to bear most inhibitory activities against Staphylococcus aureus. Such findings tend to appraise the therapeutic potential of this medicinal plant against infectious diseases. The present monograph has tried to establish the botanical description, traditional uses and the main constituents identified from PM (Bouton ex Hook.f.) Baillon. The limited documentation of in vitro assays of this plant demonstrates an urgent need for extensive research in order to validate other traditional uses and hence open new avenues for drug development. PMID:26401372

  10. The effects of turbine passage on C-start behavior of salmon at the Wanapum Dam, Washington

    Energy Technology Data Exchange (ETDEWEB)

    Cada, Glenn F. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Ryon, Michael G. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Smith, John G. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Luckett, Cloe A. [Oak Ridge Inst. for Science and Education (ORISE), Oak Ridge, TN (United States)

    2006-06-01

    In 2005, Grant County Public Utility District No. 2 (GCPUD) replaced one of the 10 Kaplan turbines at Wanapum Dam with an advanced turbine that was developed with support from the U.S. Department of Energy’s Advanced Hydropower Turbine System Program. Compared to a conventional Kaplan turbine, the advanced minimum gap runner (MGR) turbine is predicted to have lower values for several potential fish injury mechanisms, and therefore was expected to improve turbine-passage fish survival. Fish survival tests of the new turbine were carried out by GCPUD between February and April 2005. A total of 8,960 tagged juvenile summer Chinook salmon were used to quantify the differences in direct mortality associated with turbine passage for the new and old turbines. There were few test conditions in which the study was noted a distinct difference between the old Kaplan turbine and the new MGR turbine on the basis of changes in the escape behavior of uninjured fish.

  11. 77 FR 10358 - Acceptance of ASTM F963-11 as a Mandatory Consumer Product Safety Standard

    Science.gov (United States)

    2012-02-22

    ... COMMISSION 16 CFR Chapter II Acceptance of ASTM F963-11 as a Mandatory Consumer Product Safety Standard... ASTM F963-11 standard titled, Standard Consumer Safety Specifications for Toy Safety. Pursuant to section 106 of the Consumer Product Safety Improvement Act of 2008, ASTM F963-11 will become a mandatory...

  12. Application of trajectory optimization techniques to upper atmosphere sampling flights using the F4-C Phantom aircraft

    Science.gov (United States)

    Hague, D. S.; Merz, A. W.

    1975-01-01

    Altitude potential of an off-the-shelf F4-C aircraft is examined. It is shown that the standard F4-C has a maximum altitude capability in the region from 85000 to 95000 ft, depending on the minimum dynamic pressures deemed acceptable for adequate flight control. By using engine overspeed capability and by making use of prevailing winds in the stratosphere, it is suggested that the maximum altitude achievable by an F4-C should be in the vicinity of 95000 ft for routine flight operation. This altitude is well in excess of the minimum altitudes which must be achieved for monitoring the possible growth of suspected aerosol contaminants.

  13. 46 CFR 154.610 - Design temperature not colder than 0 °C (32 °F).

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Design temperature not colder than 0 °C (32 °F). 154... DANGEROUS CARGOES SAFETY STANDARDS FOR SELF-PROPELLED VESSELS CARRYING BULK LIQUEFIED GASES Design, Construction and Equipment Materials § 154.610 Design temperature not colder than 0 °C (32 °F). Materials for...

  14. Plasma Chemistry of C_3F6 and C_5F8 Gases as PFC A lternatives in an ICP Source for SiO2 Etching

    Science.gov (United States)

    Tachibana, K.; Motomura, H.; Imai, S.

    1999-10-01

    Unsaturated fluorocarbon gases such as C_3F6 and C_5F8 are potential candidates of PFC (perfluoro-compound) alternatives for dimini shing the global warming effect. We have studied gas-phase and surface reactions in plasmas of these gases as well as etching characteristics in comparison with the data taken in C_2F6 and C_4F8 plasmas. In the diagnostics of gas-phase species, polymerized species, which contain carbon atoms more than the numbers in parent molecules, are detected by electron attachment mass spectrometry (EAMS), and this tendency beocomes the largest in C_5F _8. The polymer deposition rates measured by in situ FT-IR ellipsometry ar e in the following order; C_5F8 > C_4F8 > C_3F6 > C_2F_6. This suggest that polymerized species are involved largely in the deposition. This result is consistent with the higher etching selecti vity of SiO2 to photo-resist attained in C_5F_8. Performance in the contact hole etching, however, is not deteriorated by using C_5F8 if the flow rate is controlled appropriately.

  15. Experiment of vitreous liquefaction induced by C3F8.

    Science.gov (United States)

    Wang, Jing; Li, Qiuming

    2017-01-01

    To investigate the effect and safety of vitreous liquefaction induced by C3F8 (an inert gas) injected into vitreous cavit of rabbit eyes. 24 rabbits (48 eyes) were randomly divided into four groups, named group A, group B, group C and group D, with 6 rabbits in each group. The right eye in each rabbit was taken as the experimental eye while the left as the control eye. The experimental eyes in group A were injected with 0.1mL disinfectant air; the experimental eyes in group B, group C and group D were all injected with C3F8 0.1mL, 0.2mL and 0.3mL respectively after receiving anterior chamber penetration; and the controlled eyes in all group were injected with 0.1mL balanced salt solution (BSS). During the first 7 d after injection, all the rabitts' eyes were examined by slit lamp, ophthalmoscope, intraocular pressure (IOP) and dark-adapted retina Electroretinography (ERG) each day. After that, the examination of IOG and ERP were reviewed weekly. Besides, B ultrasound should be examined to observe the situation of posterior vitreous detachment (PVD) in the 4th and 8th weeks. The rabbits were killed in the end of the 8th week, with their specimens examined by the light microscope, scanning electron microscopy (SEM) and transmission electron microscopy (TEM). Except group A, all the experimental eyes were produced with vitreous liquefaction. In group C and group D, in addition to the produced vitreous liquefaction, posterior vitreous detachment (PVD), even complete PVD, were induced in different extent. But in group B, the vitreous body was returned to the gel state at 2 weeks after gas absorption. In group C and group D, the vitreous body was not found to recover its original state at 8 weeks. In group D, there was a little increase of intraocular pressure, a mild delay of wave a and wave b after ERG in the 4th day after the gas injection. While there was no such situation in other groups. After the examination of B ultrasound in the 8th week, the complete PVD

  16. Amorphous/crystalline (A/C) thermodynamic "rules of thumb": estimating standard thermodynamic data for amorphous materials using standard data for their crystalline counterparts.

    Science.gov (United States)

    Holland, Diane; Jenkins, H Donald Brooke

    2012-05-07

    Standard thermochemical data (in the form of Δ(f)H° and Δ(f)G°) are available for crystalline (c) materials but rarely for their corresponding amorphous (a) counterparts. This paper establishes correlations between the sets of data for the two material forms (where known), which can then be used as a guideline for estimation of missing data. Accordingly, Δ(f)H°(a)/kJ mol(-1) ≈ 0.993Δ(f)H°(c)/kJ mol(-1) + 12.52 (R(2) = 0.9999; n = 50) and Δ(f)G°/kJ mol(-1) ≈ 0.988Δ(f)H°(c)/kJ mol(-1) + 0.70 (R(2) = 0.9999; n = 10). Much more tentatively, we propose that S°(298)(c)/J K(-1) mol(-1) ≈ 1.084S°(298)(c)/J K(-1) mol(-1) + 6.54 (R(2) = 0.9873; n = 11). An amorphous hydrate enthalpic version of the Difference Rule is also proposed (and tested) in the form [Δ(f)H°(M(p)X(q)·nH(2)O,a) - Δ(f)H°(M(p)X(q),a)]/kJ mol(-1) ≈ Θ(Hf)n ≈ -302.0n, where M(p)X(q)·nH(2)O represents an amorphous hydrate and M(p)X(q) the corresponding amorphous anhydrous parent salt.

  17. Hardness of CaF2 and BaF2 solid lubricants at 25 to 670 deg C

    Science.gov (United States)

    Deadmore, Daniel L.; Sliney, Harold E.

    1987-01-01

    Plastic deformation is a prominent factor in determining the lubricating value of solid lubricants. Little information is available and its direct measurement is difficult so hardness, which is an indirect measure of this property was determined for fluoride solid lubricant compositions. The Vickers hardness of BaF2 and CaF2 single crystals was measured up to 670 C in a vacuum. The orientation of the BaF2 was near the (013) plane and the CaF2 was about 16 degrees from the degrees from the (1'11) plane. The BaF2 has a hardness of 83 kg/sq mm at the 25 C and 9 at the 600 C. The CaF2 is 170 at 25 C and 13 at 670 C. The decrease in hardness in the temperature range of 25 to 100 C is very rapid and amounts to 40% for both materials. Melts of BaF2 and CaF2 were made in a platinum crucible in ambient air with compositions of 50 to 100 wt% BaF2. The Vickers hardness of these polycrystalline binary compositions at 25 C increased with increasing CaF2 reaching a maximum of 150 kn/sq mm near the eutectic. The polycrystalline CaF2 was 14% softer than that of the single crystal surface and BsF2 was 30% harder than the single crystal surface. It is estimated that the brittle to ductile transition temperature for CaF2 and BaF2 is less than 100 C for the conditions present in the hardness tester.

  18. Wind turbine sound power measurements.

    Science.gov (United States)

    Keith, Stephen E; Feder, Katya; Voicescu, Sonia A; Soukhovtsev, Victor; Denning, Allison; Tsang, Jason; Broner, Norm; Richarz, Werner; van den Berg, Frits

    2016-03-01

    This paper provides experimental validation of the sound power level data obtained from manufacturers for the ten wind turbine models examined in Health Canada's Community Noise and Health Study (CNHS). Within measurement uncertainty, the wind turbine sound power levels measured using IEC 61400-11 [(2002). (International Electrotechnical Commission, Geneva)] were consistent with the sound power level data provided by manufacturers. Based on measurements, the sound power level data were also extended to 16 Hz for calculation of C-weighted levels. The C-weighted levels were 11.5 dB higher than the A-weighted levels (standard deviation 1.7 dB). The simple relationship between A- and C- weighted levels suggests that there is unlikely to be any statistically significant difference between analysis based on either C- or A-weighted data.

  19. United States Air Force Academy (USAFA) Vertical Axis Wind Turbine.

    Science.gov (United States)

    1980-09-01

    speed ratio - blade tip speed + wind speed. -45- CONTROLCHECVMODE NON is * AD> YES Figure~ SE 22 Molrora -46N) SECTION VI TURBINE PERFORMANCE 1...Rotors, SAND76-0131. Albuquerque: July 1977. 10. Oliver, R.C. and P.R. Nixon. "Design Procedure for Coupling Savonius and Darrieus Wind Turbines ", Air...May 17-20, 1976. -65- 16. Blackwell, B.F., R.E. Sheldahl, and L.V. Feltz. Wind Tunnel Performance Data for the Darrieus Wind Turbine with NACA 0012

  20. Thermal cyclic durability testing of ceramic materials for turbine engines

    Science.gov (United States)

    Lindberg, L. J.

    1986-01-01

    The thermal cyclic durability of commercial ceramic materials for turbine engines was under evaluation since 1978. Ceramic materials are exposed to cyclic diesel-fired burner exhaust at either 1204 or 1371 C (2200 or 2500 F) for up to 3500 hours. The test conditions are selected to simulate the environment experienced by the hot flow path components in an automotive gas turbine engine. The silicon nitride and silicon carbide materials tested are the same ceramic materials currently used on the AGT100 and AGT101 ceramic turbine engine program.

  1. [Antigenicity of hepatitis C virus F protein and serum prevalence of anti-F in HCV-infected patients].

    Science.gov (United States)

    Shao, Sheng-Wen; Wu, Wen-Bin; Yu, Jian-Guo; Zhao, Ping; Qi, Zhong-Tian

    2006-12-01

    To examine the antigenicity of hepatitis C virus (HCV) F protein and investigate serum prevalence of anti-F in HCV-infected patients. Eleven pairs of overlapping primers were used to synthesize the full-length HCV f gene, from which the truncated HCV f65 gene fragment was amplified by PCR. HCV f65 gene was then cloned into pET32a(+), and transformed into E. coli strain Plyss (DE3). This recombinant E.coli was induced by IPTG for the production of HCV F65 protein. The expressed HCV F65 protein, purified by Ni-NTA agarose, was further used in ELISA to detect serum anti-F, and to immunize rabbits for making polyclonal anti-F. The rabbit polyclonal anti-F was purified by Staphylococcus aureus protein A agarose. After recombinant pET32a(+)-f65 was constructed successfully, HCV F65 protein was expressed and purified. The purified HCV F65 protein was used as a capture antigen in ELISA to detect serum anti-F in HCV infected patients (n = 30). The result showed that the mean A450 value and the positive rate of serum anti-F were 0.125+/-0.061 and 63.3%, respectively. The rabbit-derived polyclonal anti-F reacted specifically with HCV F65 protein, of which the titer was 1:30,000. Our expressed HCV F65 protein is of antigenicity, and can be used to determine serum anti-F. Anti-F IgG does exist in the sera of the HCV-infected patients. Moreover, the rabbit-derived polyclonal anti-F can be used to detect HCV F protein.

  2. Floating offshore turbines

    DEFF Research Database (Denmark)

    Tande, John Olav Giæver; Merz, Karl; Schmidt Paulsen, Uwe

    2014-01-01

    Floating wind turbines enable harvesting the offshore wind resources over deep sea. About 20 concepts are under development, at varying stages of maturity. Two concepts are demonstrated in full scale; these are HyWind and WindFloat. Both employ a standard on-shore wind turbine with only minor mod...

  3. The processing of syntactic islands – an fMRI study

    DEFF Research Database (Denmark)

    Christensen, Ken Ramshøj; Kizach, Johannes; Nyvad, Anne Mette

    2013-01-01

    The aim of this study was to investigate whether LIFG activation was sensitive to increases in syntactic working memory load triggered by multiple extractions from an embedded clause, so-called island violations, and whether there was any difference between argument and adjunct extraction. Event-...

  4. Influence of management practices on C stabilization pathways in agricultural volcanic ash soils (Canary Islands, Spain)

    Science.gov (United States)

    Hernandez, Zulimar; María Álvarez, Ana; Carral, Pilar; de Figueiredo, Tomas; Almendros, Gonzalo

    2014-05-01

    Although C stabilization mechanisms in agricultural soils are still controversial [1], a series of overlapped pathways has been suggested [2] such as: i) insolubilization of low molecular weight precursors of soil organic matter (SOM) with reactive minerals through physical and chemical bonding, ii) selective accumulation of biosynthetic substances which are recalcitrant because of its inherent chemical composition, and iii) preservation and furter diagenetic transformation of particulate SOM entrapped within resistant microaggregates, where diffusion of soil enzymes is largely hampered. In some environments where carbohydrate and N compounds are not readily biodegraded, e.g., with water saturated micropores, an ill-known C stabilization pathway may involve the formation of Maillard's reaction products [3]. In all cases, these pathways converge in the formation of recalcitrant macromolecular substances, sharing several properties with the humic acid (HA) fraction [4]. In template forests, the selective preservation and further microbial reworking of plant biomass has been identified as a prevailing mechanism in the accumulation of recalcitrant SOM forms [5]. However, in volcanic ash soils with intense organomineral interactions, condensation reactions of low molecular weight precursors with short-range minerals may be the main mechanism [6]. In order to shed some light about the effect of agricultural management on soil C stabilization processes on volcanic ash soils, the chemical composition of HA and some structural proxies of SOM informing on its origin and potential resistance to biodegradation, were examined in 30 soils from Canary Islands (Spain) by visible, infrared (IR) and 13C nuclear magnetic resonance (NMR) spectroscopies, elementary analysis and pyrolytic techniques. The results of multivariate treatments, suggested at least three simultaneous C stabilization biogeochemical trends: i) diagenetic alteration of plant biomacromolecules in soils receiving

  5. Evaluation of the efficiency of standard assessment for Category C ...

    African Journals Online (AJOL)

    This article evaluates the application and efficiency of the Ethiopian standard tax assessment, as enshrined in the Income Tax Regulation No. 78/2002, against the tax liability of Category C Taxpayers, commonly known as small business taxpayers, referring to the practice in Eastern Zone Administration of the Tigray ...

  6. RF tests on the Etam Standard C antenna

    Science.gov (United States)

    Price, R.

    1982-05-01

    Radiometric measurements on the Etam Standard C antenna are described in this paper. Gain-to-noise temperature ratio (G/T), receive and transmit gain, noise temperature, return loss, and port-to-port isolation were measured, and communication and tracking patterns taken. Because of the very low spectral flux densities in the 14/11-GHz bands, it was necessary to use radiometric methods for measuring G/T, gain and temperature. Although in Standard A antennas Y-factors range between 3 and 6 dB, in Standard C antennas they are only 0.4-0.5 dB. Thus, errors and uncertainties, which are negligible in a 6/4-GHz test, become major at 14/11 GHz. This difficulty was overcome at Etam by applying a refinement in switched radiometry, which resulted in the collection of a large amount of useful data.

  7. Using DNA Barcoding and Standardized Sampling to Compare Geographic and Habitat Differentiation of Crustaceans: A Hawaiian Islands Example

    Directory of Open Access Journals (Sweden)

    M. Julian Caley

    2011-09-01

    Full Text Available Recently, the Census of Marine Life has explored methods to assess coral reef diversity by combining standardized sampling (to permit comparison across sites with molecular techniques (to make rapid counts of species possible. To date, this approach has been applied across geographically broad scales (seven sites spanning the Indian, Pacific and Atlantic Oceans, focusing on similar habitats at all sites (10–12 m forereef. Here we examine crustacean spatial diversity patterns for a single atoll, comparing results for four sites (comprising forereef, backreef, and lagoon habitats at French Frigate Shoals (FFS, Northwestern Hawaiian Islands, Hawaii, USA, within the Papahanaumokuakea Marine National Monument. The Bray-Curtis index of similarity across these habitats at FFS was the same or greater than the similarity between similar habitats on Heron Island and Lizard Island in the Great Barrier Reef and much greater than similarity between more widely separated localities in the Indo-Pacific Ocean (e.g., Ningaloo, Moorea, French Polynesia or the Line Islands. These results imply that, at least for shallow reefs, sampling multiple locations versus sampling multiple habitats within a site maximizes the rate at which we can converge on the best global estimate of coral reef biodiversity.

  8. The use of the Almeida-Braun system in the measurement of Dutch dialect distances

    NARCIS (Netherlands)

    Heeringa, Wilbert; Braun, Angelika

    Measuring dialect distances can be based on the comparison of words, and the comparison words should be based on the comparison of sounds. In this research we used an adjusted version of an articulation-based system, developed by Almeida and Braun (1986) for finding sound distances, using the IPA

  9. Soccer fan violence: a holistic approach: a reply to Braun and Vliegenthart

    NARCIS (Netherlands)

    Spaaij, R.; Anderson, A.

    2010-01-01

    Building on Braun and Vliegenthart’s recent study of soccer hooliganism, this article develops an explanatory model of soccer fan violence and collective violence more generally. The fabric of soccer fan violence becomes a richer tapestry if the diversity of the phenomenon is recognized and the

  10. Carbon and oxygen isotope working standards from C3 and C4 photosynthates.

    Science.gov (United States)

    Spangenberg, Jorge E

    2006-09-01

    A preparation of organic working standards for the online measurement of 13C/12C and 18O/16O ratios in biological material is presented. The organic working standards are simple and inexpensive C3 and C4 carbohydrates (sugars or cellulose) from distinct geographic origin, including white sugar, toilet and XEROX papers from Switzerland, maize from Ivory Coast, cane sugar from Brazil, papyrus from Egypt, and the core of the stem of a Cyperus papyrus plant from Kenya. These photosynthetic products were compared with International Atomic Energy standards CH-3 and CH-6 and other calibration materials. The presented working standards cover a 15% range of 13C/12C ratios and 9% for 18O/16O, with a precision10.

  11. Long-lived transient anion of c-C4F8O

    Science.gov (United States)

    Kočišek, J.; Janečková, R.; Fedor, J.

    2018-02-01

    We report partial cross sections for electron attachment to c-C4F8O, a gas with promising technological applications in free-electron-rich environments. The dissociative electron attachment leads to a number of anionic fragments resulting from complex bond-breaking and bond-forming processes. However, the anion with the highest abundance is the non-dissociated (transient) parent anion which is formed around 0.9 eV electron energy. Its lifetime reaches tens of microseconds. We discuss the origin of this long lifetime, the anion's strong interactions with other molecules, and the consequences for electron-scavenging properties of c-C4F8O in denser environments, in particular for its use in mixtures with CO2 and N2.

  12. Joining of SiC[sub f]/SiC composites for thermonuclear fusion reactors

    Energy Technology Data Exchange (ETDEWEB)

    Ferraris, M. (Dipartimento di Scienza dei Materiali e Ingegneria Chimica, Politecnico di Torino, C. Duca degli Abruzzi 24, I-10129 Torino (Italy)); Badini, C. (Dipartimento di Scienza dei Materiali e Ingegneria Chimica, Politecnico di Torino, C. Duca degli Abruzzi 24, I-10129 Torino (Italy)); Montorsi, M. (Dipartimento di Scienza dei Materiali e Ingegneria Chimica, Politecnico di Torino, C. Duca degli Abruzzi 24, I-10129 Torino (Italy)); Appendino, P. (Dipartimento di Scienza dei Materiali e Ingegneria Chimica, Politecnico di Torino, C. Duca degli Abruzzi 24, I-10129 Torino (Italy)); Scholz, H.W. (Institute for Advanced Materials, CEC Joint Research Centre, I-21020 Ispra (Vatican City State, Holy See) (Italy))

    1994-09-01

    Due to their favourable radiological behaviour, SiC[sub f]/SiC composites are promising structural materials for future use in fusion reactors. A problem to cope with is the joining of the ceramic composite material (CMC) to itself for more complex structures. Maintenance concepts for a reactor made of SiC[sub f]/SiC will demand a method of joining. The joining agents should comply with the low-activation approach of the base material. With the acceptable elements Si and Mg, sandwich structures of composite/metal/composite were prepared in Ar atmosphere at temperatures just above the melting points of the metals. Another promising route is the use of joining agents of boro-silicate glasses: their composition can be tailored to obtain softening temperatures of interest for fusion applications. The glassy joint can be easily ceramised to improve thermomechanical properties. The joining interfaces were investigated by SEM-EDS, XRD and mechanical tests. ((orig.))

  13. Standardization of [sup 14]C and [sup 35]S mixtures

    Energy Technology Data Exchange (ETDEWEB)

    Grau Carles, A.; Rodriguez Barquero, L.; Grau Malonda, A. (Inst. de Investigacion Basica, Centro de Investigaciones Energeticas, Medioambientales y Tecnologicas, Madrid (Spain))

    1993-02-01

    This article examines the applicability of a newly developed method to standardize [sup 14]C and [sup 35]S mixtures in liquid scintillation spectrometry, which is an unsolved problem in the usual double window method. An improved spectrum unfolding method is applied and the spectral components and activities for [sup 14]C and [sup 35]S computed. Twenty eight assays with activity ratios for [sup 14]C and [sup 35]S between 0.1 and 12 and quench intensities which make the [sup 35]S efficiency vary from 95% to 85% are analysed. (orig.).

  14. Practical application of an advanced 12Cr rotor to 593 degree C-700MW steam turbine plant. Senshingata 12Cr ko rotor zai no 593 degree C-700MW joki turbine plant eno jitsuyoka

    Energy Technology Data Exchange (ETDEWEB)

    Kadoya, Y.; Kitai, T.; Matsuo, A.; Tsuji, I.; Kishimoto, M. (Mitsubishi Heavy Industries Ltd., Tokyo (Japan)); Tsuchiyama, T.; Okamura, M. (Kobe Steel Ltd., Kobe (Japan))

    1992-06-01

    In order to save the energy resources and to reduce the dependence on the petroleum, coal heating ultra super critical (USC) pressure thermal power plants have been paid attention. Recently, large class USC thermal power plant having a turbine inlet temperature of 593{degree}C-700MW has been planned. For middle pressure turbine rotor of this plant, advanced 12Cr steel (TMK1) which has high creep rupture property has been used. In this paper, test pieces were taken from each position of this rotor, and the quality and material properties of this rotor to be manufactured by TMK1 were evaluated. As a result, in spite of a large diameter rotor, there were no difference on the mechanical properties between the outer circumference part and the center part of the rotor, and rather good properties could be observed. Further, it could be recognized that the creep rupture property has been largely improved compared to the existing 12Cr steel. Based on these results, it was confirmed that this rotor has enough properties as a large 12Cr rotor for the steam temperature of 593{degree}C. 12 refs., 13 figs., 2 tabs.

  15. Development of standardized air-blown coal gasifier/gas turbine concepts for future electric power systems

    Energy Technology Data Exchange (ETDEWEB)

    Sadowski, R.S.; Brown, M.J.; Harriz, J.T.; Ostrowski, E.

    1991-01-01

    The cost estimate provided for the DOE sponsored study of Air Blown Coal Gasification was developed from vendor quotes obtained directly for the equipment needed in the 50 MW, 100 MW, and 200 MW sized plants and from quotes from other jobs that have been referenced to apply to the particular cycle. Quotes were generally obtained for the 100 MW cycle and a scale up/down factor was used to generate the cost estimates for the 200 MW and 50 MW cycles, respectively. Information from GTPro (property of Thermoflow, Inc.) was used to estimate the cost of the 200 MW and 50 MW gas turbine, HRSG, and steam turbines. To available the use of GTPro's estimated values for this equipment, a comparison was made between the quotes obtained for the 100 MW cycle (ABB GT 11N combustion turbine and a HSRG) against the estimated values by GTPro.

  16. F1 hybrids of BALB/c and C57BL/6 mouse strains respond differently ...

    Indian Academy of Sciences (India)

    cinogenic effects of radiation compared to the F1 hybrids of. BALB/c with SENCAR mice. They performed the experi- ments with reciprocal crosses of the two strains with SEN-. CAR mice but could not identify significant differences between the two reciprocal hybrids. Our earlier report shows significant differences in gene.

  17. Characterization of mechanically alloyed f.c.c. Ti–Mg–based powders

    CSIR Research Space (South Africa)

    Machio, Christopher N

    2010-05-01

    Full Text Available the reproducibility of the particle size 121distributions. 122The thermal behavior of the powders was determined in the range 123room temperature to 660 ?C in an argon atmosphere using a 124simultaneous thermal analyzer (Netzsch STA 449 F3 Jupiter). The 125...

  18. System Impact Study of the Eastern Grid of Sumba Island, Indonesia: Steady-State and Dynamic System Modeling for the Integration of One and Two 850-kW Wind Turbine Generators

    Energy Technology Data Exchange (ETDEWEB)

    Oswal, R. [Innovation Wind Energy, Inc., Jacksonville, FL (United States); Jain, P. [Innovation Wind Energy, Inc., Jacksonville, FL (United States); Muljadi, Eduard [National Renewable Energy Lab. (NREL), Golden, CO (United States); Hirsch, Brian [National Renewable Energy Lab. (NREL), Golden, CO (United States); Castermans, B. [Winrock International Inc., Little Rock, AR (United States); Chandra, J. [Winrock International Inc., Little Rock, AR (United States); Raharjo, S. [Winrock International Inc., Little Rock, AR (United States); Hardison, R. [Winrock International Inc., Little Rock, AR (United States)

    2016-01-01

    The goal of this project was to study the impact of integrating one and two 850-kW wind turbine generators into the eastern power system network of Sumba Island, Indonesia. A model was created for the 20-kV distribution network as it existed in the first quarter of 2015 with a peak load of 5.682 MW. Detailed data were collected for each element of the network. Load flow, short-circuit, and transient analyses were performed using DIgSILENT PowerFactory 15.2.1.

  19. On the reliability of Fusarium oxysporum f. sp. niveum research: Do we need standardized testing methods?

    Science.gov (United States)

    Fusarium oxysporum f. sp. nivium (Fon) is a pathogen highly variable in aggressiveness that requires a standardized testing method to more accurately define isolate aggressiveness (races) and to identify resistant watermelon lines. Isolates of Fon vary in aggressiveness from weakly to highly aggres...

  20. Longitudinal imaging of Alzheimer pathology using [{sup 11}C]PIB, [{sup 18}F]FDDNP and [{sup 18}F]FDG PET

    Energy Technology Data Exchange (ETDEWEB)

    Ossenkoppele, Rik; Tolboom, Nelleke; Adriaanse, Sofie F. [VU University Medical Center, Department of Neurology and Alzheimer Center, PO Box 7057, Amsterdam (Netherlands); VU University Medical Center, Department of Nuclear Medicine and PET Research, Amsterdam (Netherlands); Foster-Dingley, Jessica C.; Boellaard, Ronald; Yaqub, Maqsood; Windhorst, Albert D.; Lammertsma, Adriaan A.; Berckel, Bart N.M. van [VU University Medical Center, Department of Nuclear Medicine and PET Research, Amsterdam (Netherlands); Barkhof, Frederik [VU University Medical Center, Department of Radiology, Amsterdam (Netherlands); Scheltens, Philip [VU University Medical Center, Department of Neurology and Alzheimer Center, PO Box 7057, Amsterdam (Netherlands); Flier, Wiesje M. van der [VU University Medical Center, Department of Neurology and Alzheimer Center, PO Box 7057, Amsterdam (Netherlands); VU University Medical Center, Department of Epidemiology and Biostatistics, Amsterdam (Netherlands)

    2012-06-15

    [{sup 11}C]PIB and [{sup 18}F]FDDNP are PET tracers for in vivo detection of the neuropathology underlying Alzheimer's disease (AD). [{sup 18}F]FDG is a glucose analogue and its uptake reflects metabolic activity. The purpose of this study was to examine longitudinal changes in these tracers in patients with AD or mild cognitive impairment (MCI) and in healthy controls. Longitudinal, paired, dynamic [{sup 11}C]PIB and [{sup 18}F]FDDNP (90 min each) and static [{sup 18}F]FDG (15 min) PET scans were obtained in 11 controls, 12 MCI patients and 8 AD patients. The mean interval between baseline and follow-up was 2.5 years (range 2.0-4.0 years). Parametric [{sup 11}C]PIB and [{sup 18}F]FDDNP images of binding potential (BP{sub ND}) and [{sup 18}F]FDG standardized uptake value ratio (SUVr) images were generated. A significant increase in global cortical [{sup 11}C]PIB BP{sub ND} was found in MCI patients, but no changes were observed in AD patients or controls. Subsequent regional analysis revealed that this increase in [{sup 11}C]PIB BP{sub ND} in MCI patients was most prominent in the lateral temporal lobe (p < 0.05). For [{sup 18}F]FDDNP, no changes in global BP{sub ND} were found. [{sup 18}F]FDG uptake was reduced at follow-up in the AD group only, especially in frontal, parietal and lateral temporal lobes (all p < 0.01). Changes in global [{sup 11}C]PIB binding ({rho} = -0.42, p < 0.05) and posterior cingulate [{sup 18}F]FDG uptake ({rho} = 0.54, p < 0.01) were correlated with changes in Mini-Mental-State Examination score over time across groups, whilst changes in [{sup 18}F]FDDNP binding ({rho} = -0.18, p = 0.35) were not. [{sup 11}C]PIB and [{sup 18}F]FDG track molecular changes in different stages of AD. We found increased amyloid load in MCI patients and progressive metabolic impairment in AD patients. [{sup 18}F]FDDNP seems to be less useful for examining disease progression. (orig.)

  1. 26 CFR 5c.168(f)(8)-5 - Term of lease.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 14 2010-04-01 2010-04-01 false Term of lease. 5c.168(f)(8)-5 Section 5c.168(f... (CONTINUED) TEMPORARY INCOME TAX REGULATIONS UNDER THE ECONOMIC RECOVERY TAX ACT OF 1981 § 5c.168(f)(8)-5 Term of lease. (a) Term of lease—Basic rules. To qualify as a lease under section 168(f)(8) and § 5c...

  2. NODC Standard Format Marine Mammals of Coastal Alaska Data (1979-1991): Sighting and Census (F127) (NODC Accession 0014197)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NODC maintains data in three NODC Standard Format Marine Mammal Data Sets: Marine Mammal Sighting and Census (F127); Marine Mammal Specimens (F025); Marine Mammal...

  3. NODC Standard Format Marine Mammals of Coastal Alaska Data (1975-1981): Marine Mammal Specimens (F025) (NODC Accession 0014150)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NODC maintains data in three NODC Standard Format Marine Mammal Data Sets: Marine Mammal Sighting and Census (F127); Marine Mammal Specimens (F025); Marine Mammal...

  4. Development of a Primary Standard for Calibration of [{sup 18}F]FDG Activity Measurement Systems

    Energy Technology Data Exchange (ETDEWEB)

    Capogni, M [ENEA Istituto Nazionale di Metrologia delle Radiazioni Ionizzanti (INMRI), Centro Ricerche Casaccia, I-00060 Rome (Italy); Felice, P De [ENEA Istituto Nazionale di Metrologia delle Radiazioni Ionizzanti (INMRI), Centro Ricerche Casaccia, I-00060 Rome (Italy); Fazio, A [ENEA Istituto Nazionale di Metrologia delle Radiazioni Ionizzanti (INMRI), Centro Ricerche Casaccia, I-00060 Rome (Italy); Simonelli, F [Institute for Health and Consumer Protection, Joint Research Centre (JRC), European Commission, I-21020 Ispra (Vatican City State, Holy See,), Italy; D' Ursi, V [Amersham Health Srl (AH), I-13040 Saluggia (Saint Vincent and the Grenadines), Italy; Pecorale, A [Amersham Health Srl (AH), I-13040 Saluggia (Saint Vincent and the Grenadines), Italy; Giliberti, C [Istituto Superiore per la Prevenzione e la Sicurezza del Lavoro (ISPESL), I-00184 Rome (Italy); Abbas, K [Institute for Health and Consumer Protection, Joint Research Centre (JRC), European Commission, I-21020 Ispra (Vatican City State, Holy See,), Italy

    2006-05-15

    The {sup 18}F national primary standard was developed by the INMRI-ENEA using the 4{pi}{beta} Liquid Scintillation Spectrometry Method with {sup 3}H-Standard Efficiency Tracing. Measurements were performed at JRCIspra under a scientific collaboration between the Institute for Health and Consumer Production, the Amersham Health and the National Institute for Occupational Safety and Prevention (ISPESL). The goal of the work was to calibrate, with minimum uncertainty, the INMRI-ENEA transfer standard portable well-type ionisation chamber as well as other JRC-Ispra and Amersham Health reference Ionising Chambers used for FDG activity measurement.

  5. F-8C digital CCV flight control laws

    Science.gov (United States)

    Hartmann, G. L.; Hauge, J. A.; Hendrick, R. C.

    1976-01-01

    A set of digital flight control laws were designed for the NASA F-8C digital fly-by-wire aircraft. The control laws emphasize Control Configured Vehicle (CCV) benefits. Specific pitch axis objectives were improved handling qualities, angle-of-attack limiting, gust alleviation, drag reduction in steady and maneuvering flight, and a capability to fly with reduced static stability. The lateral-directional design objectives were improved Dutch roll damping and turn coordination over a wide range in angle-of-attack. An overall program objective was to explore the use of modern control design methodilogy to achieve these specific CCV benefits. Tests for verifying system integrity, an experimental design for handling qualities evaluation, and recommended flight test investigations were specified.

  6. Type-specific dynamic measurements on wind turbines at the test site Schnittlingen (Germany, F.R.)

    Science.gov (United States)

    Boehnisch, Helmut; Kussmann, Alfred; Reiniger, Klaus; Thiesen, Reimer

    1988-12-01

    Results of research on recording high dynamical data from rotating systems are presented. Two telemetry PCM (pulse code modulation) systems are used. The data of high-speed short-term measurement campaigns and of the long-time measurements are preprocessed on the test site process computers for averaging and first verification. Final evaluation of the data is done off-line on the DFVLR (Deutsche Forschungs und Versuchsanstalt fuer Luft und Raumfahrt) main frame computers. Of special interest are weather conditions, particularly their influence on the behavior of the control system and on the performance of wind turbines. Typical analyzed data of the tested turbines and interesting weather conditions are presented. A list of experiences and recommendations on wind test work are given.

  7. Risk Factors for Cervical Pain in F-15C Pilots.

    Science.gov (United States)

    Chumbley, Eric M; Stolfi, Adrienne; McEachen, James C

    2017-11-01

    Many fighter pilots report cervical pain during their careers. Etiology likely relates to +Gz exposure, physical positioning with maneuvers, and varying load associated with headgear. We evaluated whether selected risk factors predicted cervical pain in this population. An Institutional Review Board-approved, Health Insurance Portability and Accountability Act-compliant, controlled crossover study of the use of home cervical traction was undertaken with 20 male F-15C pilots. We recorded pilot age (mean 38 yr, range 34-49), total high-G hours (2338 h, range 1038-4645), and previous neck problems and measured cervical range of motion. For 12 wk, pilots logged pre- and postflight pain, whether the Joint Helmet Mounted Cueing System (JHMCS) was employed, maximum +Gz experienced, and sortie duration. Pain with and without JHMCS was compared using paired t-tests and correlations assessed with Pearson or Spearman coefficients. Mean flight-related pain increased by 0.73 on the numerical rating scale with JHMCS and 0.52 without. Neck extension coupled with JHMCS use correlated negatively with increased pain (r = -0.551). Higher numbers of previously reported neck problems correlated with pain when using JHMCS (r = 0.629). Age, maximum +Gz per sortie, total high-Gz hours flown, and hours per sortie did not correlate. To our knowledge, this is the first prospective evaluation of risk factors for fighter pilots' cervical pain. Neck pain was significantly worse with JHMCS use and with flexed posture or history of prior neck problems combined with JHMCS use. This information will help guide countermeasure development for high-G pilots.Chumbley EM, Stolfi A, McEachen JC. Risk factors for cervical pain in F-15C pilots. Aerosp Med Hum Perform. 2017; 88(11):1000-1007.

  8. Ring Puckering Potentials of Three Fluorinated Cyclopentenes: C_5F_8, C_5HF_7, and C_5H_2F_6

    Science.gov (United States)

    Arsenault, E. A.; Long, B. E.; Pringle, Wallace C.; Choi, Yoon Jeong; Cooke, S. A.; Ocola, Esther J.; Laane, Jaan

    2015-06-01

    A systematic study on the ring puckering potentials of three fluorinated cyclopentenes has been performed using Fourier transform microwave spectroscopy in tandem with quantum chemical calculations. Spectra between 8 GHz and 16 GHz have been measured for octafluorocyclopentene, 1H-heptafluorocyclopentene, and 1H,2H-hexafluorocyclopentene, where the hydrogens sequentially replace the fluorines on the sp^2 hybridized carbons. Rotational constants and centrifugal distortion constants have been determined for the parent species and all 13C isotopologues. In regards to the ring puckering, double minimum potential, both cross state and intra-state transitions were observed for all molecules except the 1H,2H-hexafluorocyclopentene. Experimental Coriolis coupling constants and ΔE01 values will be presented and discussed. The ring puckering barrier heights for C_5F_8, C_5HF_7, and C_5H_2F_6, have been calculated to be 222 wn, 302 wn, and 367 wn, respectively.

  9. Harmonisation of wind turbine certification in Europe JOULE project EWTC

    Energy Technology Data Exchange (ETDEWEB)

    Nath, C. [Germanischer Lloyd, Hamburg (Germany); Eriksson, C. [Det Norske Veritas, Hellerup (Denmark); Hulle, F. van [Frans van Hulle, Petten (Netherlands); Skamris, C. [Risoe National Lab., Roskilde (Denmark); Stam, W. [CIWI Holland, Arnheim (Netherlands); Vionis, P. [CRES, Attki (Greece)

    1999-03-01

    Wind turbine certification requirements are currently fairly divers within Europe. Therefore the leading European certification bodies initiated a JOULE project to harmonise the certification procedure on the basis of the current set of IEC/EN 61400 series standards. The paper presents a review of the state of the art of wind turbine certification in European countries and an outline of the sturcture of the project. The main steps of the project are (a) the collection of differences in certification practices by round robin certification of three wind turbine types; (b) assessment of the different certification results and (c) the development of a harmonised certification procedure. (au) EU-JOULE-3. 19 refs.

  10. A New Adaptive Response Surface Model for Reliability Analysis of 2.5D C/SiC Composite Turbine Blade

    Science.gov (United States)

    Chang, Yaning; Sun, Zhigang; Sun, Weiyi; Song, Yingdong

    2017-11-01

    In order to calculate the failure probability of complex structures such as a 2.5D/SiC composites turbine blade and improve the structure safety, a new adaptive model of Response Surface (RS) analysis has been developed in this paper, which can improve the computational efficiency of structural failure problem while ensure the accuracy. The Gaussian Process Regression (GPR) theory was used to establish the RS and reconstruct the performance function of structure. And, an Adaptive Latin hypercube Sampling (ALHS) strategy was adopted in the process of establishing and correcting the RS. Finally the Direct Simulation Monte Carlo(DSMC)was utilized to calculate the failure probability of the performance function replacing the complex structure. Two numerical examples were calculated to validate the accuracy and computational efficiency of the proposed method. Additionally the finite element stress analysis results of 2.5D C/SiC composite turbine blade were used to structural reliability analysis by the proposed method. The approach in this paper provides a new way to evaluate the risk of the complex structures.

  11. Gas--steam turbine combined cycle power plants

    Energy Technology Data Exchange (ETDEWEB)

    Christian, J.E.

    1978-10-01

    The purpose of this technology evaluation is to provide performance and cost characteristics of the combined gas and steam turbine, cycle system applied to an Integrated Community Energy System (ICES). To date, most of the applications of combined cycles have been for electric power generation only. The basic gas--steam turbine combined cycle consists of: (1) a gas turbine-generator set, (2) a waste-heat recovery boiler in the gas turbine exhaust stream designed to produce steam, and (3) a steam turbine acting as a bottoming cycle. Because modification of the standard steam portion of the combined cycle would be necessary to recover waste heat at a useful temperature (> 212/sup 0/F), some sacrifice in the potential conversion efficiency is necessary at this temperature. The total energy efficiency ((electric power + recovered waste heat) divided by input fuel energy) varies from about 65 to 73% at full load to 34 to 49% at 20% rated electric power output. Two major factors that must be considered when installing a gas--steam turbine combines cycle are: the realiability of the gas turbine portion of the cycle, and the availability of liquid and gas fuels or the feasibility of hooking up with a coal gasification/liquefaction process.

  12. Fundamentals for remote structural health monitoring of wind turbine blades - a preproject. Annex C. Fibre transducer for damage detection in adhesive layers of wind turbine blades

    DEFF Research Database (Denmark)

    Sendrup, P.

    2002-01-01

    -bends and a suggestion for a micro-bend transducer design specifically suitable for detection of damage in adhesive layers between larger composite structures, as the shellsin a wind turbine blade. Such a damage will cause the joined parts to move slightly relative to each other, and the transducer is designed to change...

  13. Chemical constituents of Breynia vitis-idaea (Burm. f.) C. E. C. Fischer

    Science.gov (United States)

    Nguyen, Thao-My; Le, Xuan-Tien; Nguyen, Minh-Tam K.

    2017-09-01

    This study investigated the antioxidant and tyrosinase inhibition activities of Breynia vitis-idaea (Burm.f.) C. E. C. Fischer leaves extracts using in vitro assays; and isolated bioactive compounds from the fractioned extract which showed the best properties by column chromatography. All extracts showed significant radical scavenging and tyrosinase inhibition activities. Ethyl acetate extracts and their isolated compounds showed the highest free biocapacities. In addition, from ethyl acetate extracts, two pure compounds were elucidated as 6-O-benzoylarbutin (1) and Breynioside B (2); another compound, 6-O-benzoyl-α-D-glucose (3) was also isolated and elucidated from n-butanol extracts.

  14. The biomechanical properties of F1C pili

    CERN Document Server

    Castelain, Mickaël; Klinth, Jeanna; Lindberg, Stina; Andersson, Magnus; Uhlin, Bernt Eric; Axner, Ove

    2014-01-01

    Uropathogenic Escherichia coli (UPEC) express various kinds of organelles, so-called pili or fimbriae, that mediate adhesion to host tissue in the urinary tract through specific receptor-adhesin interactions. The biomechanical properties of these pili have been considered important for the ability of bacteria to withstand shear forces from rinsing urine flows. Force measuring optical tweezers have been used to characterize individual organelles of F1C type expressed by UPEC bacteria with respect to such properties. Qualitatively, the force-vs.-elongation response was found to be similar to that of other types of helix-like pili expressed by UPEC, i.e. type 1, P, and S, with force-induced elongation in three regions of which one represents the important uncoiling mechanism of the helix-like quaternary structure. Quantitatively, the steady-state uncoiling force was assessed to 26.4(1.4) pN, which is similar to those of other pili (which range from 21 pN for SI to 30 pN for type 1). The corner velocity for dynam...

  15. Phase description of the Huber-Braun neuron model for mammalian cold receptors

    Science.gov (United States)

    Freund, J. A.; Finke, C.; Braun, H. A.; Feudel, U.

    2013-10-01

    The spiking activity of mammalian cold receptors is described by the Huber-Braun neuron model. Sweeping temperature as a control parameter across a biologically relevant range this model exhibits a complex bifurcation structure seen in the sequence of interspike intervals. The model's distinctive feature is the interaction between a fast spike generating dynamics and a slow subthreshold oscillation. Viewing the spike generation as a cycle, the dynamics may also be modeled phenomenologically by two phases, one for the spike cycle and the second for the slow subthreshold oscillation. In fact, a phase model of temperature-dependent mammalian cold receptors was already proposed by Roper et al. (2000). Here we follow their approach and investigate to what extent this model is able to reproduce the bifurcation patterns of the Huber-Braun model. Special attention is paid to the tonic firing to bursting transition observed in the low temperature range.

  16. A vinylic Rosenmund-von Braun reaction: practical synthesis of acrylonitriles.

    Science.gov (United States)

    Pradal, Alexandre; Evano, Gwilherm

    2014-10-14

    An efficient system based on acetone cyanohydrin and catalytic amounts of copper(I) iodide and 1,10-phenanthroline is reported for the cyanation of alkenyl iodides. A wide range of polysubstituted acrylonitriles could be obtained in fair to good yields and with complete retention of the geometry of the double bond. This extension of the Rosenmund-von Braun reaction also enabled a straightforward formal synthesis of the naturally occurring acrylonitrile alliarinoside.

  17. Improvement of the thermal conductivity of SiC{sub F}/SiC composite

    Energy Technology Data Exchange (ETDEWEB)

    Youngblood, G.E. [Pacific Northwest National Laboratory, Richland, WA (United States); Kowbel, W. [MER Corporation, Tucson, AZ (United States)

    1996-04-01

    The methods, high temperature annealing and doping, were examined for improving the thermal conductivity of simulated CVI/{Beta}-SiC matrix material. For instance, a two hour 1500{degrees}C anneal led to the increase of the room temperature (RT) thermal conductivity from 38 to 59 W.mK. Be doping was even more effective in causing the thermal conductivity to increase with RT conductivity values up to 160 W/mK attained. To further optimize the thermal conductivity, hot-pressed SiC materials with carefully controlled amounts of Be-and B{sub 4}C-doping were investigated. Although a small improvement ({approx} 8%) was achieved with 2.0 wt % Be-doping, the effort to refine the amount of doping needed was largely unsuccessful. Apparently, hot-pressing SiC introduced numerous substructural stacking faults which effectively scattered phonons on the intermediate temperature range and nullified the benefits of doping. Nevertheless, Be and B{sub 4}C-doping and/or thermal treatments appear to be promising strategies to achieve the goal of eventually improving the thermal conductivity of SiC{sub f}/SiC composite.

  18. Telaprevir- and boceprevir-based tritherapies in real practice for F3-F4 pretreated hepatitis C virus patients.

    Science.gov (United States)

    Bonnet, Delphine; Guivarch, Matthieu; Bérard, Emilie; Combis, Jean-Marc; Remy, Andre Jean; Glibert, Andre; Payen, Jean-Louis; Metivier, Sophie; Barange, Karl; Desmorat, Herve; Palacin, Anaïs; Nicot, Florence; Abravanel, Florence; Alric, Laurent

    2014-09-27

    To assess, in a routine practice setting, the sustained virologic response (SVR) to telaprevir (TPV) or boceprevir (BOC) in hepatitis C virus (HCV) null-responders or relapsers with severe liver fibrosis. One hundred twenty-five patients were treated prospectively for 48 wk with TPV or BOC + pegylated-interferon (peg-INF) α2a + ribavirin (PR) according to standard treatment schedules without randomization. These patients were treated in routine practice settings in 10 public or private health care centers, and the data were prospectively collected. Only patients with severe liver fibrosis (Metavir scores of F3 or F4 upon liver biopsy or liver stiffness assessed by elastography), genotype 1 HCV and who were null-responders or relapsers to prior PR combination therapy were included in this study. The Metavir fibrosis scores were F3 in 35 (28%) and F4 in 90 (72%) of the patients. In total, 62.9% of the patients were null-responders and 37.1% relapsers to the previous PR therapy. The overall SVR rate at 24 wk post-treatment withdrawal was 59.8%. The SVR was 65.9% in the TPV group and 44.1% in the BOC group. Independent predictive factors of an SVR included a response to previous treatment, relapsers vs null-responders [OR = 3.9; (1.4, 10.6), P = 0.0084], a rapid virological response (RVR) [OR 6.9 (2.6, 18.2), P = 0.001] and liver stiffness lower than 21.3 kPa [OR = 8.2 (2.3, 29.5), P = 0.001]. During treatment, 63 patients (50.8%) had at least one severe adverse event (SAE) of grade 3 or 4. A multivariate analysis identified two factors associated with SAEs: female gender [OR = 2.4 (1.1, 5.6), P = 0.037] and a platelet count below 150 × 10(3)/ mm(3) [OR = 5.3 (2.3, 12.4), P ≤ 0.001]. More than half of these difficult-to-treat patients achieved an SVR and had SAEs in an actual practice setting. The SVR rate was influenced by the response to previous PR treatment, the RVR and liver stiffness.

  19. Telaprevir- and boceprevir-based tritherapies in real practice for F3-F4 pretreated hepatitis C virus patients

    Science.gov (United States)

    Bonnet, Delphine; Guivarch, Matthieu; Bérard, Emilie; Combis, Jean-Marc; Remy, Andre Jean; Glibert, Andre; Payen, Jean-Louis; Metivier, Sophie; Barange, Karl; Desmorat, Herve; Palacin, Anaïs; Nicot, Florence; Abravanel, Florence; Alric, Laurent

    2014-01-01

    AIM: To assess, in a routine practice setting, the sustained virologic response (SVR) to telaprevir (TPV) or boceprevir (BOC) in hepatitis C virus (HCV) null-responders or relapsers with severe liver fibrosis. METHODS: One hundred twenty-five patients were treated prospectively for 48 wk with TPV or BOC + pegylated-interferon (peg-INF) α2a + ribavirin (PR) according to standard treatment schedules without randomization. These patients were treated in routine practice settings in 10 public or private health care centers, and the data were prospectively collected. Only patients with severe liver fibrosis (Metavir scores of F3 or F4 upon liver biopsy or liver stiffness assessed by elastography), genotype 1 HCV and who were null-responders or relapsers to prior PR combination therapy were included in this study. RESULTS: The Metavir fibrosis scores were F3 in 35 (28%) and F4 in 90 (72%) of the patients. In total, 62.9% of the patients were null-responders and 37.1% relapsers to the previous PR therapy. The overall SVR rate at 24 wk post-treatment withdrawal was 59.8%. The SVR was 65.9% in the TPV group and 44.1% in the BOC group. Independent predictive factors of an SVR included a response to previous treatment, relapsers vs null-responders [OR = 3.9; (1.4, 10.6), P = 0.0084], a rapid virological response (RVR) [OR 6.9 (2.6, 18.2), P = 0.001] and liver stiffness lower than 21.3 kPa [OR = 8.2 (2.3, 29.5), P = 0.001]. During treatment, 63 patients (50.8%) had at least one severe adverse event (SAE) of grade 3 or 4. A multivariate analysis identified two factors associated with SAEs: female gender [OR = 2.4 (1.1, 5.6), P = 0.037] and a platelet count below 150 × 103/ mm3 [OR = 5.3 (2.3, 12.4), P ≤ 0.001]. CONCLUSION: More than half of these difficult-to-treat patients achieved an SVR and had SAEs in an actual practice setting. The SVR rate was influenced by the response to previous PR treatment, the RVR and liver stiffness. PMID:25276282

  20. Electron attachment, ionization and drift in c-C4F8

    Science.gov (United States)

    de Urquijo, J.; Basurto, E.

    2001-05-01

    The pulsed Townsend method has been used to measure the drift velocity ve and the density-normalized effective ionization coefficient (α-η)/N, (α and η are the ionization and attachment coefficients, respectively) in c-C4F8 over the density-normalized electric field strength E/N, 12 Td≤E/N≤43 Td and 330 Td≤E/N≤600 Td (1 Td = 10-17 V cm2), at pressures between 1 and 7.5 Torr (1 Torr = 133.3 Pa). For 12 Td≤E/N≤43 Td, the above parameters were found to be pressure independent, while for the range 330 Td≤E/N≤600 Td an inverse dependence of the above coefficients was found for gas pressures less than 2 Torr. Such dependence is believed to be due to the autodetachment of the originally formed, unstable parent negative ion c-C4F8-*. At low E/N, no previous data for ve or (α-η)/N were found for comparison with the present data. A critical field strength of E/Ncrit = 439.5 Td, for which α = η, was found to be in good agreement with previous data.

  1. Billroth II with Braun Enteroenterostomy Is a Good Alternative Reconstruction to Roux-en-Y Gastrojejunostomy in Laparoscopic Distal Gastrectomy

    Directory of Open Access Journals (Sweden)

    Long-Hai Cui

    2017-01-01

    Full Text Available Background. Although Billroth II (BII reconstruction is simpler and faster than Billroth I or Roux-en-Y (RY reconstruction in patients undergoing totally laparoscopic distal gastrectomy (TLDG, BII reconstruction is associated with several complications, including more severe bile reflux. BII Braun anastomosis may be a better alternative to RY reconstruction. Methods. This retrospective study included 56 consecutive patients who underwent TLDG for gastric cancer, followed by BII Braun or RY reconstruction, between January 2013 and December 2015. Surgical outcomes, including length of operation, quantity of blood lost, and postoperative complications, were compared in the two groups. Results. Clinicopathological characteristics did not differ between the BII Braun and RY groups. Mean length of operation was significantly longer in the RY than the BII Braun group (157.3 min versus 134.6 min, p < 0.010, but length of hospital stay, blood loss, and complication rate did not differ between the two groups. Ileus occurred in three patients (10.0% in the RY group. Endoscopic findings 6 months after surgery showed bile reflux in seven (28% patients in the BII Braun group and five (17.2% in the RY group (p = 0.343, but no significant differences in rate of gastric residue or degree of gastritis in the remnant stomach in the two groups. Conclusions. B-II Braun anastomosis is a good alternative to RY reconstruction, reducing length of operation and ileus after TLDG.

  2. Standardized uptake value and quantification of metabolism for breast cancer imaging with FDG and L-[1-C-11]tyrosine PET

    NARCIS (Netherlands)

    Kole, AC; Nieweg, OE; Pruim, J; Paans, AMJ; Plukker, JTM; Hoekstra, HJ; Vaalburg, W; Schraffordt Koops, H.

    The aims of the study were to compare the value of L-[1-C-11]tyrosine (TYR) and [F-18]fluoro-2-deoxy-D-glucose (FDG) as tumor tracers in patients with breast cancer, to investigate the correlation between quantitative values and standardized uptake values (SUVs) and to estimate the value of SUVs for

  3. A Fault Diagnosis Approach for Gas Turbine Exhaust Gas Temperature Based on Fuzzy C-Means Clustering and Support Vector Machine

    Directory of Open Access Journals (Sweden)

    Zhi-tao Wang

    2015-01-01

    Full Text Available As an important gas path performance parameter of gas turbine, exhaust gas temperature (EGT can represent the thermal health condition of gas turbine. In order to monitor and diagnose the EGT effectively, a fusion approach based on fuzzy C-means (FCM clustering algorithm and support vector machine (SVM classification model is proposed in this paper. Considering the distribution characteristics of gas turbine EGT, FCM clustering algorithm is used to realize clustering analysis and obtain the state pattern, on the basis of which the preclassification of EGT is completed. Then, SVM multiclassification model is designed to carry out the state pattern recognition and fault diagnosis. As an example, the historical monitoring data of EGT from an industrial gas turbine is analyzed and used to verify the performance of the fusion fault diagnosis approach presented in this paper. The results show that this approach can make full use of the unsupervised feature extraction ability of FCM clustering algorithm and the sample classification generalization properties of SVM multiclassification model, which offers an effective way to realize the online condition recognition and fault diagnosis of gas turbine EGT.

  4. The results of pre-design studies on the development of a new design of gas turbine compressor package of GPA-C-16 type

    Science.gov (United States)

    Smirnov, A. V.; Chobenko, V. M.; Shcherbakov, O. M.; Ushakov, S. M.; Parafiynyk, V. P.; Sereda, R. M.

    2017-08-01

    The article summarizes the results of analysis of data concerning the operation of turbocompressor packages at compressor stations for the natural gas transmission system of Ukraine. The basic requirements for gas turbine compressor packages used for modernization and reconstruction of compressor stations are considered. Using a 16 MW gas turbine package GPA-C-16S/76-1,44M1 as an example, the results of pre-design studies and some technical solutions that improve the energy efficiency of gas turbine compressor packages and their reliability, as well as its environmental performance are given. In particular, the article deals with the matching of performance characteristics of a centrifugal compressor (hereinafter compressor) and gas turbine drive to reduce fuel gas consumption; as well as application of energy efficient technologies, in particular, exhaust gas heat recovery units and gas-oil heat exchangers in turbocompressor packages oil system; as well as reducing emissions of carbon monoxide into the atmosphere using a catalytic exhaust system. Described technical solutions can be used for development of other types of gas turbine compressor packages.

  5. Randomized trial comparing episiotomies with Braun-Stadler episiotomy scissors and EPISCISSORS-60®

    Directory of Open Access Journals (Sweden)

    Sawant G

    2015-06-01

    Full Text Available Ganpat Sawant, Divya Kumar Dr DY Patil Medical College and Hospital, Nerul, Navi Mumbai, India Introduction: Episiotomy angle is a crucial factor in causation of obstetric anal sphincter injuries (OASIS, which are the major cause of female bowel incontinence. Sutured episiotomies angled too close to the midline (<30 degree or too far away from the midline (.60 degree fail to unload the perineum sufficiently and predispose to OASIS. A 25-degree post-delivery episiotomy suture angle has a 10% risk of OASIS while 45-degree episiotomy is associated with 0.5% risk. To account for perineal distension at crowning, a 60-degree episiotomy incision is required to achieve 43–50 degree suture angles. We compared episiotomy suture angles with commonly used Braun-Stadler episiotomy scissors with the new fixed angle EPISCISSORS-60®. Methods: Ethical approval was obtained. A prospective cluster randomization design was chosen. Thirty-one patients were required in each group for a 12-degree difference with power at 90% and 5% significance. Sutured episiotomy angles and post-delivery linear distance from caudal end of the sutured episiotomy to the anus were measured with protractors and rulers. Two-tailed t-tests were used to compare the two groups. Results: Thirty-one nulliparae had episiotomies with EPISCISSORS-60®, 32 with Braun-Stadler. Mean age (25 versus 24.8 years was similar. EPISCISSORS-60® episiotomies were angled 12 degrees more laterally away from the anus compared to Braun-Stadler (40.6 degrees, 95% confidence interval [CI] ±2, interquartile range [IQR] 35–45 versus 28.3 degrees, 95% CI ±2, IQR 25–30, P<0.0001. The post-delivery linear distance from caudal end of the sutured episiotomy to the anus was 15 mm more with the EPISCISSORS-60® compared to Braun-Stadler (35 mm, 95% CI ±2.2, IQR =30–39 versus 19.5; 95% CI ±1.3, IQR =14.75–22.25 P<0.0001. EPISCISSORS-60® episiotomies measured longer (47 mm versus 40 mm, P<0.0001. There were

  6. Interrupted E2F1-miR-34c-SCF negative feedback loop by hyper-methylation promotes colorectal cancer cell proliferation.

    Science.gov (United States)

    Yang, Shu; Wu, Bo; Sun, Haimei; Ji, Fengqing; Sun, Tingyi; Zhao, Yan; Zhou, Deshan

    2015-12-24

    Tumour suppressor miR-34c deficiency resulted from hyper-methylation in its promoter is believed to be one of the main causes of colorectal cancer (CRC). Till date, miR-34c has been validated as a direct target of p53; but previous evidence suggested other transcription factor(s) must be involved in miR-34c transcription. In the present study, we in the first place identified a core promoter region (-1118 to -883 bp) of pre-miR-34c which was embedded within a hyper-methylated CpG island. Secondly, E2F1 promoted miR-34c transcription by physical interaction with the miR-34c promoter at site -897 to -889 bp. The transcriptional activating effect of E2F1 on miR-34c was in a p53 independent manner but profoundly promoted in the presence of p53 with exposure to 5-aza-2'-deoxycytidine (DAC). Thirdly, stem cell factor (SCF), a miR-34c target, was specifically reduced upon an introduction of E2F1 which lead to suppression of CRC cell proliferation. The E2F1-suppressed cell proliferation was partially abrogated by additional miR-34c inhibitor, indicating that the anti-proliferation effect of E2F1 was probably through activating miR-34c-SCF axis. Finally, SCF/KIT signalling increased E2F1 production by reducing its proteosomal degradation dependent on PI3K/Akt-GSK3β pathway. In conclusion, our results suggested the existence of E2F1-miR-34c-SCF negative feedback loop which was interrupted by the hyper-methylation of miR-34c promoter in CRC cells and increased cell proliferation. © 2016 Authors.

  7. 11 CFR 100.29 - Electioneering communication (2 U.S.C. 434(f)(3)).

    Science.gov (United States)

    2010-01-01

    ....S.C. 431) General Definitions § 100.29 Electioneering communication (2 U.S.C. 434(f)(3)). (a... the definition of electioneering communication. Any communication that: (1) Is publicly disseminated... 11 Federal Elections 1 2010-01-01 2010-01-01 false Electioneering communication (2 U.S.C. 434(f)(3...

  8. 26 CFR 5c.168(f)(8)-11 - Consolidated returns. [Reserved

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 14 2010-04-01 2010-04-01 false Consolidated returns. 5c.168(f)(8)-11 Section 5c.168(f)(8)-11 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) TEMPORARY INCOME TAX REGULATIONS UNDER THE ECONOMIC RECOVERY TAX ACT OF 1981 § 5c...

  9. 26 CFR 5c.168(f)(8)-3 - Requirements for lessor.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 14 2010-04-01 2010-04-01 false Requirements for lessor. 5c.168(f)(8)-3 Section 5c.168(f)(8)-3 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) TEMPORARY INCOME TAX REGULATIONS UNDER THE ECONOMIC RECOVERY TAX ACT OF 1981 § 5c...

  10. 26 CFR 5c.168(f)(8)-6 - Qualified leased property.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 14 2010-04-01 2010-04-01 false Qualified leased property. 5c.168(f)(8)-6 Section 5c.168(f)(8)-6 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) TEMPORARY INCOME TAX REGULATIONS UNDER THE ECONOMIC RECOVERY TAX ACT OF 1981 § 5c...

  11. 26 CFR 5c.168(f)(8)-1 - Special rules for leases.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 14 2010-04-01 2010-04-01 false Special rules for leases. 5c.168(f)(8)-1 Section 5c.168(f)(8)-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) TEMPORARY INCOME TAX REGULATIONS UNDER THE ECONOMIC RECOVERY TAX ACT OF 1981 § 5c...

  12. 26 CFR 5c.168(f)(8)-10 - Leases between related parties. [Reserved

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 14 2010-04-01 2010-04-01 false Leases between related parties. 5c.168(f)(8)-10 Section 5c.168(f)(8)-10 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) TEMPORARY INCOME TAX REGULATIONS UNDER THE ECONOMIC RECOVERY TAX ACT OF 1981 § 5c...

  13. 26 CFR 5c.44F-1 - Leases and qualified research expenses.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 14 2010-04-01 2010-04-01 false Leases and qualified research expenses. 5c.44F-1 Section 5c.44F-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) TEMPORARY INCOME TAX REGULATIONS UNDER THE ECONOMIC RECOVERY TAX ACT OF 1981 § 5c...

  14. Kwajalein, Marshall Island, Bucholz. Revised Uniform Summary of Surface Weather Observations (RUSSWO). Parts A-F

    Science.gov (United States)

    1973-06-08

    J 107!> FOM1210 WS jUI. 64 O,|S,5 lOLI ) PA ls[IVIO S O010 F$0 THIS lORM A01 00S00)i| A .-.-- - -’* q t if DATA PROCESSING BRANCH EXTREME VALUES...1 994] 94.9 99.4 So 960 99~ loli 99,v 99, Y 99,’ Z919, 9, 9 0:9 9,0 99,0 9 , 00 , ¢,010 9.1,{0 400o 96.5 9,1 99,Z 99&4 . ,9 99, 71 eo . 9 ,9 4 le * A 9

  15. 31 CFR 315.32 - Series A, B, C, D, F, G, J, and K bonds.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Series A, B, C, D, F, G, J, and K.... SAVINGS BONDS, SERIES A, B, C, D, E, F, G, H, J, AND K, AND U.S. SAVINGS NOTES Interest § 315.32 Series A, B, C, D, F, G, J, and K bonds. All bonds of these series have matured and no longer earn interest. ...

  16. Monofluorinated analogues of polychlorinated biphenyls (F-PCBs) - standards for analysis. Retention behaviour in gas chromatography and MS characteristics

    Energy Technology Data Exchange (ETDEWEB)

    Johansen, J.E.; Liu, H. [CHIRON, Trondheim (Norway); Luthe, G. [NTNU, Trondheim (Norway); Leonards, P. [RIVO, Ijmuiden (Netherlands)

    2004-09-15

    Polychlorinated biphenyls (PCBs) have been the subject of a broad range of studies and investigations, because they are persistent organic pollutants (POPs). There is a concern about the health effects of PCB exposure. PCBs are structurally similar to polychlorinated dibenzodioxines (PCDDs) and polychlorinated dibenzofuranes (PCDFs) as well as to polybrominated dibenzoethers (PBDEs). Their abundance as pollutants stems from their worldwide manufacture as heavy-used industrial chemicals. The overwhelming problem with PCBs is their continuing environmental impact; their persistence, and widespread prior use has caused global contamination of soil, rivers and other waterways that can affect our food and water supplies. The high lipophilicity causes accumulation in body lipids and liver organs, and subsequent bioaccumulation in the food chain. Therefore, they have to be determined very frequently at the trace level in, e.g. water, food, sediment and soil. The sample preparation and final determination may well lead to systematic and non-systematic (random) errors. It is generally accepted that the accurate determination of micro contaminants in such complex mixtures requires the use of external or, preferably, internal standards (ISs). The benefit of using ISs with physico-chemical properties similar to those of the target compounds, is that both types of errors will be minimized. While preliminary work on monofluorinated polycyclic aromatic hydrocarbons (F-PAHs) as ISs in gas chromatography (GC) was very promising, we recently synthesized a series of monofluorinated PCBs (F-PCBs). We found that they are a very promising set of internal standards for trace-level analysis of PCBs and are alternatives to {sup 13}C-labelled analogues. In the present study, we focused attention on the retention behavior of F-PCBs in GC, and MS characteristics, with the intention to use them as calibration standards for GC-MS and electron capture detection (GCECD).

  17. Comparison of API & IEC Standards for Offshore Wind Turbine Applications in the U.S. Atlantic Ocean: Phase II; March 9, 2009 - September 9, 2009

    Energy Technology Data Exchange (ETDEWEB)

    Jha, A.; Dolan, D.; Gur, T.; Soyoz, S.; Alpdogan, C.

    2013-01-01

    This report compares two design guidelines for offshore wind turbines: Recommended Practice for Planning, Designing, and Constructing Fixed Offshore Platform Structures and the International Electrotechnical Commission 61400-3 Design Requirements for Offshore Wind Turbines.

  18. Comparative Study of Thermal Shock Behavior with Fabrication Method of SiC{sub f}/SiC Composite

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Dong Hee; Park, Kwang Heon [Kyunghee University, Seoul (Korea, Republic of); Kim, Weon Ju; Park, Ji Yeon; Kim, Dae Jong; Lee, Hyeon Geun [KAERI, Daejeon (Korea, Republic of)

    2016-05-15

    An active search is ongoing for an alternative material to be used for manufacturing of nuclear fuel cladding. Studies are currently aimed at improving the safety of this cladding. In particular, ceramic-based nuclear fuel cladding, such as SiC, is receiving much attention due to the excellent radiation resistance, high strength, chemical durability against oxidation and corrosion, and excellent thermal conduction of ceramics. SiC{sub f}f/SiC composite cladding is required to maintain soundness against destruction and corrosion, and have excellent thermal conductivity to remove sufficiently the heat generated by nuclear fuel in output operation. For the reason, SiCf/SiC composite layers with densification are needed in SiC fiber bundle. As manufacturing methods to fill SiC matrix phase, there are Liquid Silicon Infiltration (LSI), Chemical Vapor Infiltration (CVI), Slurry Infiltration and Hot Pressure Sintering (SI-HPS), Polymer Infiltration and Pyrolysis (PIP), and Hybrid processes in combination of multiple processes (CVI+PIP, CVI{sub R}S and PIP+RS). This study conducted a comparison analysis, based on the manufacturing method, of the thermal shock behavior of metal cladding that had an SiC composite protective film added. The SiC{sub f}/SiC composite layer and the Zry-4 surface were separated, and cracks occurred in the SiC{sub f}/SiC composite. In the case of the cladding that had the SiC{sub f}/SiC composite protective film manufactured by the CVI process, there was no microcrack inside the SiC{sub f}/SiC composite. A microcracks that penetrated the fiber was observed inside the SiC{sub f}/SiC composite when it was manufactured using the PIP process; this was due to the absence of an interphase coating that increased the fracture toughness of the fiber.

  19. VizieR Online Data Catalog: C/2012 F6 (Lemmon) and C/2012 S1 (ISON) maps (Cordiner+, 2014)

    Science.gov (United States)

    Cordiner, M. A.; Remijan, A. J.; Boissier, J.; Milam, S. N.; Mumma, M. J.; Charnley, S. B.; Paganini, L.; Villanueva, G.; Bockelee-Morvan, D.; Kuan, Y.-J.; Chuang, Y.-L.; Lis, D. C.; Biver, N.; Crovisier, J.; Minniti, D.; Coulson, I. M.

    2017-04-01

    WCS-calibrated fits image files of the molecular flux maps shown in Figure 1 for HCN, HNC and H2CO observed in comets C/2012 F6 (Lemmon) and C/2012 S1 (ISON) using ALMA. The files are labeled with the corresponding comet and molecule names. The files are standard two-dimensional fits images, which can be opened in fits image viewers such as SAOimage DS9, CASA viewer, or Starlink Gaia. GIMP and Adobe Photoshop can also be used, provided the appropriate plugins are present. The images contain flux values (in units of Jansky km/s per beam), as a function of celestial coordinate in the J2000 equatorial system. Due to the cometary motions, the absolute coordinate systems are accurate only at the start of the observations (dates and times are given in Table 1). These images are the result of integrating the (3D) ALMA data cubes over the full widths of the observed spectral lines (equivalent to collapsing the data cubes along their respective spectral/velocity axes). The beam dimensions (BMAJ and BMIN), corresponding to the angular resolution of the images, are given in the image headers in units of degrees. object.dat : -------------------------------------------------------------------------------- Code Name Elem q e i H1 d AU deg mag -------------------------------------------------------------------------------- C/2012 F6 Lemmon 2456375.5 0.7312461 0.9985125 82.607966 7.96 C/2012 S1 Ison 2456624.5 0.0124515 0.9998921 64.401571 6.11 (2 data files).

  20. An analysis of type F2 software measurement standards for profile surface texture parameters

    Science.gov (United States)

    Todhunter, L. D.; Leach, R. K.; Lawes, S. D. A.; Blateyron, F.

    2017-06-01

    This paper reports on an in-depth analysis of ISO 5436 part 2 type F2 reference software for the calculation of profile surface texture parameters that has been performed on the input, implementation and output results of the reference software developed by the National Physical Laboratory (NPL), the National Institute of Standards and Technology (NIST) and Physikalisch-Technische Bundesanstalt (PTB). Surface texture parameters have been calculated for a selection of 17 test data files obtained from the type F1 reference data sets on offer from NPL and NIST. The surface texture parameter calculation results show some disagreements between the software methods of the National Metrology Institutes. These disagreements have been investigated further, and some potential explanations are given.

  1. Progress in the development of a SiC{sub f}/SiC creep test

    Energy Technology Data Exchange (ETDEWEB)

    Hamilton, M.L.; Lewinsohn, C.A.; Jones, R.H.; Youngblood, G.E.; Garner, F.A. [Pacific Northwest National Lab., Richland, WA (United States); Hecht, S.L.

    1996-10-01

    An effort is now underway to design an experiment that will allow the irradiation creep behavior of SiC{sub f}/SiC composites to be quantified. Numerous difficulties must be overcome to achieve this goal, including determining an appropriate specimen geometry that will fit their radiation volumes available and developing a fabrication procedure for such a specimen. A specimen design has been selected, and development of fabrication methods is proceeding. Thermal and stress analyses are being performed to evaluate the viability of the specimen and to assist with determining the design parameters. A possible alternate type of creep test is also being considered. Progress in each of these areas is described in this report.

  2. Standard-C hydrogen monitoring system acceptance test procedure

    Energy Technology Data Exchange (ETDEWEB)

    Schneider, T.C.

    1994-09-02

    The primary function of the standard-C hydrogen monitoring system (SHMS) is to monitor specifically for hydrogen in the waste tank atmosphere which may also contain (but not be limited to) unknown quantities of air, nitrous oxide, ammonia, water vapor, carbon dioxide, carbon monoxide, and other gaseous constituents. The SHMS will consist of hydrogen specific monitors, a grab sampler to collect samples for laboratory analysis, a gas chromatograph, and the gas sample collection system necessary to support the operation of the instrumentation. This system will be located in a cabinet placed at the tank of interest. The purpose of this document is to demonstrate that the SHMS is constructed as intended by design.

  3. Genetic studies on the Senegal population. II. Polymorphisms of the plasma proteins F13A, F13B, ORM1, AHSG, C6, C7, and APOC2.

    Science.gov (United States)

    Corbo, R M; Scacchi, R; Cossu, G; Brega, A; Scozzari, R

    1994-10-01

    Using isoelectric focusing and immunoblotting techniques, we tested 270 plasma samples from 3 populations of Senegal (Wolof, Peul, Tukulor) to determine genetic variation at 7 protein loci (F13A, F13B, ORM1, AHSG, C6, C7, APOC2). Four of the seven systems (F13A, ORM1, AHSG, C6) have not been studied previously in sub-Saharan Africa, and one system (C7) has never been examined in any population of African ancestry. The assumption that F13B*6, F13B*23, and APOC2*2 represent African marker alleles is supported by this study. At the AHSG locus we observed a four-allele polymorphism rather than the two-allele polymorphism commonly seen in other ethnic groups. At the C6 locus, in addition to the two common alleles C6*A and C6*B, we observed three other alleles, one of which (C6*A3), found at polymorphic frequencies, seems to be another example of a unique African allele. The C7 locus was found to be monomorphic in the Peul but polymorphic in the Wolof and the Tukulor. At the F13A and ORM1 loci, Senegalese have allele frequencies similar to those reported for American blacks. All three Senegalese samples display typical African features, such as a high frequency of the F13B*2 allele and the presence of the APOC2*2 allele at a polymorphic level. However, some differences in allele frequencies have been found between the three groups, and this could have implications for reconstructing their remote history.(ABSTRACT TRUNCATED AT 250 WORDS)

  4. Prevalence of the C282Y mutation for haemochromatosis on the Island of Majorca.

    Science.gov (United States)

    Guix, P; Picornell, A; Parera, M; Tomás, C; Muncunill, J; Castro, J A; Rossell, J; Vaquer, P; Ramon, M M; Obrador, A

    2000-08-01

    The C282Y mutation of the HFE gene has been reported to be present in most of the patients with hereditary haemochromatosis (HH) of Northern European ancestry. HH affects approximately 1/300 individuals, but it is not evenly distributed in the different European countries. In the present study, polymerase chain reaction (PCR) and restriction-enzyme digestion were used to analyse the frequency of the most important mutation in haemochromatosis (C282Y) in subjects from Majorca (Balearic Islands, Spain) and patients with haemochromatosis. The results were compared with other studies from Spain and Europe. A total of 420 Majorcan chromosomes were analysed and the C282Y mutation was observed at a frequency of 2.62%+/-0.8 (11 heterozygotes: eight men and three women). In the group of hereditary haemochromatosis probands, 13 out of 14 were homozygous for the C282Y mutation. In the distribution of the C282Y mutation, a north-west to south-east cline was detected, supporting the Celtic origin of this mutation.

  5. 26 CFR 5c.168(f)(8)-4 - Minimum investment of lessor.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 14 2010-04-01 2010-04-01 false Minimum investment of lessor. 5c.168(f)(8)-4....168(f)(8)-4 Minimum investment of lessor. (a) Minimum investment. Under section 168(f)(8)(B)(ii), an... has a minimum at risk investment which, at the time the property is placed in service under the lease...

  6. Purity and radioactive decay behaviour of industrial 2D-reinforced SiC[sub f]/SiC composites

    Energy Technology Data Exchange (ETDEWEB)

    Scholz, H.W. (Institute for Advanced Materials, CEC Joint Research Centre, I-21020 Ispra (Vatican City State, Holy See) (Italy)); Zucchetti, M. (Dipartimento di Energetica, Politecnico di Torino, C. Duca degli Abruzzi 24, I-10129 Torino (Italy)); Casteleyn, K. (Institute for Advanced Materials, CEC Joint Research Centre, I-21020 Ispra (Vatican City State, Holy See) (Italy)); Adelhelm, C. (IMF I, Kernforschungszentrum Karlsruhe GmbH, Postfach 3640, D-76344 Karlsruhe (Germany))

    1994-09-01

    Ceramic matrix composites based on SiC with continuous fibres (SiC[sub f]/SiC) are considered promising structural materials for future fusion devices. It was still to clarify, whether impurities in industrial SiC[sub f]/SiC could jeopardise radiological advantages. Experimental impurity analyses revealed a two-dimensionally reinforced SiC[sub f]/SiC with the matrix produced by CVI as very pure. Chemo-spectrometric methods were combined with radioactivation methods (CPAA, NAA). A quantification of the main constituents Si, C and O was added. Calculations with the FISPACT-2.4 code and EAF-2 library identified elements detrimental for different low-activation criteria. For the neutron exposure, EEF reactor-study first wall and blanket conditions were simulated. The calculated SiC[sub f]/SiC included 48 trace elements. Even under conservative assumptions, all low-activation limits of European interest are fulfilled. Exclusively the hands-on recycling limit for the First Wall can intrinsically not be satisfied with SiC. The theoretical goal of a SiC[sub f]/SiC depleted of [sup 28]Si (isotopic tailoring) is critically discussed. ((orig.))

  7. 2C-Methyl-d-erythritol 4-phosphate enhances and sustains cyclodiphosphate synthase IspF activity

    Science.gov (United States)

    Bitok, J. Kipchirchir; Freel Meyers, Caren

    2012-01-01

    There is significant progress toward understanding catalysis throughout the essential MEP pathway to isoprenoids in human pathogens; however, little is known about pathway regulation. The present study begins by testing the hypothesis that isoprenoid biosynthesis is regulated via feedback inhibition of the fifth enzyme cyclodiphosphate IspF by downstream isoprenoid diphosphates. Here, we demonstrate recombinant E. coli IspF is not inhibited by downstream metabolites and isopentenyl diphosphate (IDP), dimethylallyl diphosphate (DMADP), geranyl diphosphate (GDP) and farnesyl diphosphate (FDP) under standard assay conditions. However, 2C-methyl-d-erythritol 4-phosphate (MEP), the product of reductoisomerase IspC and first committed MEP pathway intermediate, activates and sustains this enhanced IspF activity, and the IspF-MEP complex is inhibited by FDP. We further show that the methylerythritol scaffold itself, which is unique to this pathway, drives the activation and stabilization of active IspF. Our results suggest a novel feed-forward regulatory mechanism for 2Cmethyl-d-erythritol 2,4-cyclodiphosphate (MEcDP) production and support an isoprenoid biosynthesis regulatory mechanism via feedback inhibition of the IspF-MEP complex by FDP. The results have important implications for development of inhibitors against the IspF-MEP complex, which may be the physiologically relevant form of the enzyme. PMID:22839733

  8. Standardized, systemic phenotypic analysis of Slc12a1I299F mutant mice.

    Science.gov (United States)

    Kemter, Elisabeth; Rathkolb, Birgit; Becker, Lore; Bolle, Ines; Busch, Dirk H; Dalke, Claudia; Elvert, Ralf; Favor, Jack; Graw, Jochen; Hans, Wolfgang; Ivandic, Boris; Kalaydjiev, Svetoslav; Klopstock, Thomas; Rácz, Ildikó; Rozman, Jan; Schrewe, Anja; Schulz, Holger; Zimmer, Andreas; Fuchs, Helmut; Gailus-Durner, Valérie; Hrabe de Angelis, Martin; Wolf, Eckhard; Aigner, Bernhard

    2014-08-02

    Type I Bartter syndrome is a recessive human nephropathy caused by loss-of-function mutations in the SLC12A1 gene coding for the Na+-K+-2Cl- cotransporter NKCC2. We recently established the mutant mouse line Slc12a1I299F exhibiting kidney defects highly similar to the late-onset manifestation of this hereditary human disease. Besides the kidney defects, low blood pressure and osteopenia were revealed in the homozygous mutant mice which were also described in humans. Beside its strong expression in the kidney, NKCC2 has been also shown to be expressed in other tissues in rodents i.e. the gastrointestinal tract, pancreatic beta cells, and specific compartments of the ear, nasal tissue and eye. To examine if, besides kidney defects, further organ systems and/or metabolic pathways are affected by the Slc12a1I299F mutation as primary or secondary effects, we describe a standardized, systemic phenotypic analysis of the mutant mouse line Slc12a1I299F in the German Mouse Clinic. Slc12a1I299F homozygous mutant mice and Slc12a1I299F heterozygous mutant littermates as controls were tested at the age of 4-6 months. Beside the already published changes in blood pressure and bone metabolism, a significantly lower body weight and fat content were found as new phenotypes for Slc12a1I299F homozygous mutant mice. Small additional effects included a mild erythropenic anemia in homozygous mutant males as well as a slight hyperalgesia in homozygous mutant females. For other functions, such as immunology, lung function and neurology, no distinct alterations were observed. In this systemic analysis no clear primary effects of the Slc12a1I299F mutation appeared for the organs other than the kidneys where Slc12a1 expression has been described. On the other hand, long-term effects additional and/or secondary to the kidney lesions might also appear in humans harboring SLC12A1 mutations.

  9. AGT (Advanced Gas Turbine) technology project

    Science.gov (United States)

    1988-01-01

    An overall summary documentation is provided for the Advanced Gas Turbine Technology Project conducted by the Allison Gas Turbine Division of General Motors. This advanced, high risk work was initiated in October 1979 under charter from the U.S. Congress to promote an engine for transportation that would provide an alternate to reciprocating spark ignition (SI) engines for the U.S. automotive industry and simultaneously establish the feasibility of advanced ceramic materials for hot section components to be used in an automotive gas turbine. As this program evolved, dictates of available funding, Government charter, and technical developments caused program emphases to focus on the development and demonstration of the ceramic turbine hot section and away from the development of engine and powertrain technologies and subsequent vehicular demonstrations. Program technical performance concluded in June 1987. The AGT 100 program successfully achieved project objectives with significant technology advances. Specific AGT 100 program achievements are: (1) Ceramic component feasibility for use in gas turbine engines has been demonstrated; (2) A new, 100 hp engine was designed, fabricated, and tested for 572 hour at operating temperatures to 2200 F, uncooled; (3) Statistical design methodology has been applied and correlated to experimental data acquired from over 5500 hour of rig and engine testing; (4) Ceramic component processing capability has progressed from a rudimentary level able to fabricate simple parts to a sophisticated level able to provide complex geometries such as rotors and scrolls; (5) Required improvements for monolithic and composite ceramic gas turbine components to meet automotive reliability, performance, and cost goals have been identified; (6) The combustor design demonstrated lower emissions than 1986 Federal Standards on methanol, JP-5, and diesel fuel. Thus, the potential for meeting emission standards and multifuel capability has been initiated

  10. A Pilot Study of Rapid Hepatitis C Testing in Probation and Parole Populations in Rhode Island.

    Science.gov (United States)

    Zaller, Nickolas D; Patry, Emily J; Bazerman, Lauri B; Noska, Amanda; Kuo, Irene; Kurth, Ann; Beckwith, Curt G

    2016-01-01

    Hepatitis C virus (HCV) affects between five and seven million individuals in the United States and chronic infection can lead to liver disease, cirrhosis, and hepatocellular carcinoma. Probation/parole offices are a novel setting for rapid HCV testing, providing outreach to populations at increased risk for HCV infection and/or transmitting HCV to others. While some correctional facilities offer HCV testing, many individuals who present to probation/parole offices are never or briefly incarcerated and may not access medical services. We conducted a rapid HCV testing pilot at probation/parole offices in Rhode Island. Overall, 130 people accepted rapid HCV testing, of whom 12 had reactive tests. Only four of these individuals presented to a community-based clinic for confirmatory testing, despite being offered a monetary incentive. Identifying and addressing barriers to HCV confirmatory testing and follow-up care is critical to increasing the uptake of HCV care and treatment in this vulnerable population.

  11. Cordia dichotomoa Forst. f Syn. C. obliqua Willd. (English: Sebesten ...

    Indian Academy of Sciences (India)

    ropes, cordage and paper pulp. The fruit is an astringent and is used in affections o.f urinary passages, diseases o.llllngs and spleen. The decoction of bark is used infevers. The kernels are used in treating ring-worm. The leaves are used in treating ulcers and headache. The plant is used as an antidote to snake-bite.

  12. Impact of the novel hepatotropic viruslike agent NV-F during chronic hepatitis C virus infection.

    Science.gov (United States)

    Yeh, Chau-Ting; Hsu, Chao-Wei; Chang, Ming-Ling; Tsao, Mei-Ling

    2008-12-15

    NV-F is a novel hepatotropic viruslike agent. To investigate the impact of the NV-F agent during chronic hepatitis C virus (HCV) infection, 101 consecutive patients with chronic HCV infection were evaluated. NV-F DNA in serum samples and NV-F antigen expression in liver tissues were assessed. All patients subsequently received a 6-month course of interferon-based antiviral therapy. Of the 101 patients, 30 (29.7%) were positive for serum NV-F DNA. Immunohistochemical analysis revealed positive NV-F antigen expression in the liver in 14 of these 30 patients. Patients positive for serum NV-F DNA had significantly higher serum aminotransferase levels (P F DNA. In conclusion, coinfection of the NV-F agent in chronic HCV infection is associated with more severe hepatitis activity.

  13. Wind turbine blade with viscoelastic damping

    Science.gov (United States)

    Sievers, Ryan A.; Mullings, Justin L.

    2017-01-10

    A wind turbine blade (60) damped by viscoelastic material (54, 54A-F) sandwiched between stiffer load-bearing sublayers (52A, 52B, 56A, 56B) in portions of the blade effective to damp oscillations (38) of the blade. The viscoelastic material may be located in one or more of: a forward portion (54A) of the shell, an aft portion (54D) of the shell, pressure and suction side end caps (54B) of an internal spar, internal webbing walls (54C, 54E), and a trailing edge core (54F).

  14. Necessary and Sufficient Standards Closure Process pilot: F- and H-Area groundwater remediation

    Energy Technology Data Exchange (ETDEWEB)

    Bullington, M.

    1995-09-25

    The DOE Standards Committee`s Necessary and Sufficient (N and S) Standards Closure Process was piloted at SRS on the F- and H- Area Seepage Basins Groundwater Remediation Project. For this existing Environmental Restoration project, the set of N and S standards for design and safety documentation were identified, independently confirmed and approved. Implementation of these standards on the project can lead to a $2.8 Million cost savings on the design, construction/installation, and safety documentation scope of $18 Million. These savings were primarily from site design of power distribution and piping for the water treatment units. Also contributing to the savings were a more appropriate level of safety documentation and the alternate ``commercial`` bids made by vendors in response to a request for proposals for water treatment units. The use of the N and S Process on an ER activity, details on the cost savings, lessons learned and recommendations for broader implementation of the N and S Process are described herein.

  15. Post-bomb coral Δ14C record from Iki Island, Japan: possible evidence of oceanographic conditions on the northern East China Sea shelf

    Science.gov (United States)

    Mitsuguchi, Takehiro; Hirota, Masashi; Group, Paleo Labo AMS Dating; Yamazaki, Atsuko; Watanabe, Tsuyoshi; Yamano, Hiroya

    2016-10-01

    In this study, a sea-surface water Δ14C record of AD 1966-2000 (i.e., after the atmospheric nuclear-bomb testing period of the mid-1950s to early 1960s) was reconstructed from a coral sample collected from Iki Island, western Japan. The island is located in the Tsushima Strait where the Tsushima Current flows from the East China Sea (ECS) continental shelf into the Sea of Japan, indicating a strong influence of the ECS shelf water on the island. It is widely accepted that the Tsushima Current originates in the area between the ECS shelf break and the Nansei Islands further offshore as a branch of the Kuroshio Current, although another possible origin is the Taiwan-Tsushima Current System. The Δ14C record from Iki Island shows the following evidence of a response to the atmospheric nuclear testing: (1) an increase from ~55‰ in 1966 to ~133‰ in 1970, (2) a plateau ranging between ~123 and ~142‰ during the 1970s to the late 1980s, and (3) a gradual decrease from ~115‰ in 1990 to ~83‰ in 2000. Comparison of this record with coral Δ14C records from the Nansei Islands (Okinawa Island, Ishigaki Island and Kikai Island), located ~160-280 km off the ECS shelf break and little influenced by the shelf water, suggests that the surface-water Δ14C around Iki Island was ~30-45‰ lower than that of the Nansei Islands from the mid-1960s to late 1970s, and that the Δ14C difference between Iki Island and the Nansei Islands decreased from the end of the 1970s to ~0-15‰ in the mid-1980s to 2000. The lower Δ14C around Iki Island can be explained as follows: (1) in contrast to the Nansei Islands area, the ECS shelf area is a vertically mixed, highly concentrated carbon reservoir significantly connected to subsurface and deeper waters outside the shelf area, strongly suggesting that the surface-water Δ14C of the shelf area (perhaps excepting very shallow innermost shelf areas) was significantly less sensitive to the atmospheric nuclear-bomb 14C spike than that of the

  16. C3F gene mutation is involved in the susceptibility to pre-eclampsia.

    Science.gov (United States)

    Rhim, Mohamed Salah; Meddeb, Sawsen; Kaabia, Ons; Jalloul, Mohamed; Sakouhi, Mohamed; Jrzad, Besma Bel Hadj; Felah, Raja

    2015-05-01

    The aim of this study was to analyze the functional polymorphism of exon 3 of the gene of complement component C3 (rs 2230199) to identify the potential involvement of the mutated gene C3F in the genesis of pre-eclampsia. It is a comparative case-control study conducted in the university center of maternity and neonatology of Monastir with collaboration of high institute of biotechnology (Tunisia) on a period of 2 years. Two hundred and fifty patients and 96 newborns divided into pre-eclampsia group (150 parturients with pre-eclampsia and 48 newborns) and control group (100 parturients with normal pregnancy and their 48 infants) are taken. Each patient and control were sampled for the phenotypic study and the molecular analysis. The ARMS-PCR (amplification refractory mutation system) was the standard procedure in our study. A simple observation let to distinguish three cases of genotypes: SS, FF and SF. In the control group, 56% of parturients had the genotype SS, 38%, the genotype SF and 6%, FF genotype. In the pre-eclamptic population, SS, SF, and FF genotypes were determined, respectively, 40, 45.30 and 14.60% of the patients. There is a sharp increase in the frequency of the FF genotype in pre-eclamptic patients compared to controls (14.60 vs. 6%). The difference was statistically significant (p = 0.01). The frequencies of C3S and alleles C3F determined in controls (respectively, 74 and 26%) were different from those identified in pre-eclamptic patients (respectively, 62.60 and 37.30%). This difference was statistically significant (p = 0.005). The C3S and C3F allele frequencies determined in control newborns (respectively, 83.33 and 16.66%) were slightly different from those identified in newborn issued from pre-eclamptic patients (respectively, 80.2 and 19.79%), but the difference was not statistically significant (p = 0.67). The gene polymorphism of complement component C3 was significantly associated with the onset of pre-eclampsia. These results should be

  17. Ligand versus Complex: C-F and C-H Bond Activation of Polyfluoroaromatics at a Cyclic (Alkyl)(Amino)Carbene.

    Science.gov (United States)

    Paul, Ursula S D; Radius, Udo

    2017-03-17

    C-F and C-H bond activation reactions of polyfluoroaromatics at the cyclic (alkyl)(amino)carbene (cAAC) cAACmethyl (1) are reported. Studies on the C-F bond activation using the cAAC-stabilized nickel(0) complex [Ni(cAACmethyl )2 ] (2) have shown that 2 does not react with fluorinated arenes. However, these investigations led to the observation of C-F bond cleavage of perfluorinated arenes by the carbene ligand cAACmethyl (1) itself. The reaction of 1 with C6 F6 , C6 F5 -C6 F5 , C6 F5 -CF3 , and C5 F5 N afforded the insertion products of cAAC into one of the C-F bonds of the substrate, that is, the C-F bond activation products (cAACmethyl )F(Arf ) (Arf =C6 F5 4 a, C6 F4 -C6 F5 4 b, C6 F4 -CF3 4 c, C5 F4 N 4 d). These products decompose readily upon heating to 80 °C within a few hours in solution with formation of ionic iminium salts [(cAACmethyl )(Arf )][X] 6 a-d or neutral alkenyl perfluoroaryl imine compounds 7 a-d. The compounds (cAACmethyl )F(Arf ) 4 a-d readily transfer fluoride, which has been exemplified by the fluoride transfer of all compounds using BF3 etherate as fluoride acceptor. Fluoride transfer has also been achieved starting from (cAACmethyl )F(C6 F4 -CF3 ) (4 c) or (cAACmethyl )F(C5 F4 N) (4 d) to other selected substrates such as trimethylchlorosilane, benzoyl chloride and tosyl chloride. Instead of C-F bond activation, insertion of the cAAC into the C-H bond was observed if 1 was treated with the partially fluorinated arenes C6 F5 H, 1,2,4,5-C6 F4 H2 , 1,3,5-C6 F3 H3 , and 1,3-C6 F2 H4 . The compounds (cAACmethyl )H(Arf ) (Arf =C6 F5 12 e, 2,3,5,6-C6 F4 H 12 f, 2,4,6-C6 F3 H2 12 g and 2,6-C6 F2 H3 12 h) have been isolated in good yields and have been characterized including X-ray analysis. Fluorobenzene C6 FH5 (pKa ≈37), the least C-H acidic fluoroarene used in this study, does not react. In order to investigate the scope and limitations of this type of cAAC C-H bond activation reaction, cAACmethyl (1) was treated

  18. C5 Extract Induces Apoptosis in B16F10 Murine Melanoma Cells ...

    African Journals Online (AJOL)

    Purpose: To investigate the anti-cancer activities of C5 extract (C5E), a new herbal preparation from. Korea, on B16F10 cells. Methods: The anti-proliferative effects of C5E were assessed by culturing B16F10 cells in the presence or absence of C5E. Cell cycle progression was analyzed by PI staining using flow cytometry.

  19. C5 Extract Induces Apoptosis in B16F10 Murine Melanoma Cells ...

    African Journals Online (AJOL)

    The quantities of apoptosis-inducing proteins were measured by Western blot. Results: C5E inhibited the proliferation of B16F10 cells but not human keratinocytes. C5E induced S phase arrest by interfering with cell regulatory factors such as cyclins B1, D1, D3, and E, and cyclindependent kinase 2, in B16F10 cells.

  20. The Darrieus wind turbine for electrical power generation

    Science.gov (United States)

    Robinson, M. L.

    1981-06-01

    Aspects of wind as an energy source and the momentum theory of wind turbines are briefly examined. Types of Darrieus wind turbine are described; attention is given to a turbine with airfoil blades curved in troposkein form, and a turbine with straight blades of fixed or variable pitch. The Darrieus vertical-axis wind turbine is then considered with regard to aerodynamics, annual energy output, structures, control systems, and energy storage. Brief reviews of selected Darrieus wind turbine projects are given, including those at Magdalen Islands, Canada, Sandia Laboratories, Reading University, and Australia and New Zealand.

  1. Interlaboratory Study (ILS) for F 548-01, The Standard Test Method for Intensity of Scratches on Aerospace Transparent Plastics

    National Research Council Canada - National Science Library

    Pinkus, Alan

    2003-01-01

    ...) as outlined in ASTM E 691. This report, which conforms to the ILS reporting format required by ASTM, describes the study that was conducted for ASTM test standard F 548-01, Intensity of Scratches on Aerospace Transparent Plastics...

  2. Standardization and a multilaboratory comparison of Neisseria meningitidis serogroup A and C serum bactericidal assays. The Multilaboratory Study Group.

    Science.gov (United States)

    Maslanka, S E; Gheesling, L L; Libutti, D E; Donaldson, K B; Harakeh, H S; Dykes, J K; Arhin, F F; Devi, S J; Frasch, C E; Huang, J C; Kriz-Kuzemenska, P; Lemmon, R D; Lorange, M; Peeters, C C; Quataert, S; Tai, J Y; Carlone, G M

    1997-03-01

    A standardized serum bactericidal assay (SBA) is required to evaluate the functional activity of antibody produced in response to Neisseria meningitidis serogroup A and C vaccines. We evaluated assay parameters (assay buffer, target strains, growth of target cells, target cell number, complement source and concentration, and methods for growth of surviving bacteria) which may affect the reproducibility of SBA titers. The various assay parameters and specificity of anticapsular antibody to five serogroup A strains (A1, ATCC 13077, F8238, F9205, and F7485) and four serogroup C strains (C11, G7880, G8050, and 1002-90) were evaluated with Centers for Disease Control and Prevention meningococcal quality control sera. The critical assay parameters for the reproducible measurement of SBA titers were found to include the target strain, assay incubation time, and complement. The resulting standardized SBA was used by 10 laboratories to measure functional anticapsular antibody against serogroup A strains F8238 and serogroup C strain C11. In the multilaboratory study, SBA titers were measured in duplicate for 14 pairs of sera (seven adults and seven children) before and after immunization with a quadrivalent polysaccharide (A, C, Y, and W-135) vaccine. The standardized SBA was reliable in all laboratories regardless of experience in performing SBAs. For most sera, intralaboratory reproducibility was +/- 1 dilution; interlaboratory reproducibility was +/- 2 dilutions. The correlation between median titers (interlaboratory) and enzyme-linked immunosorbent assay total antibody concentrations was high for both serogroup A (r = 0.86; P < 0.001; slope = 0.5) and serogroup C (n = 0.86; P < 0.001; slope = 0.7). The specified assay, which includes the critical parameters of target strain, incubation time, and complement source, will facilitate interlaboratory comparisons of the functional antibody produced in response to current or developing serogroup A and C meningococcal vaccines.

  3. ASTM F1717 standard for the preclinical evaluation of posterior spinal fixators: can we improve it?

    Science.gov (United States)

    La Barbera, Luigi; Galbusera, Fabio; Villa, Tomaso; Costa, Francesco; Wilke, Hans-Joachim

    2014-10-01

    Preclinical evaluation of spinal implants is a necessary step to ensure their reliability and safety before implantation. The American Society for Testing and Materials reapproved F1717 standard for the assessment of mechanical properties of posterior spinal fixators, which simulates a vertebrectomy model and recommends mimicking vertebral bodies using polyethylene blocks. This set-up should represent the clinical use, but available data in the literature are few. Anatomical parameters depending on the spinal level were compared to published data or measurements on biplanar stereoradiography on 13 patients. Other mechanical variables, describing implant design were considered, and all parameters were investigated using a numerical parametric finite element model. Stress values were calculated by considering either the combination of the average values for each parameter or their worst-case combination depending on the spinal level. The standard set-up represents quite well the anatomy of an instrumented average thoracolumbar segment. The stress on the pedicular screw is significantly influenced by the lever arm of the applied load, the unsupported screw length, the position of the centre of rotation of the functional spine unit and the pedicular inclination with respect to the sagittal plane. The worst-case combination of parameters demonstrates that devices implanted below T5 could potentially undergo higher stresses than those described in the standard suggestions (maximum increase of 22.2% at L1). We propose to revise F1717 in order to describe the anatomical worst case condition we found at L1 level: this will guarantee higher safety of the implant for a wider population of patients. © IMechE 2014.

  4. Two new species of Phyllodistomum Braun, 1899 (Trematoda: Gorgoderidae Looss, 1899) from Great Barrier Reef fishes.

    Science.gov (United States)

    Ho, Hei Wa; Bray, Rodney A; Cutmore, Scott C; Ward, Selina; Cribb, Thomas H

    2014-03-19

    Two new species of Phyllodistomum Braun, 1899 are described from the urinary bladder of fishes of the Great Barrier Reef. Phyllodistomum hoggettae n. sp. is described from Plectropomus leopardus (leopard coralgrouper) (Serranidae) and P. vaili n. sp. is described from Mulloidichthys vanicolensis (yellowfin goatfish) and M. flavolineatus (yellowstripe goatfish) (Mullidae). These species are compared with 26 previously described marine Phyllodistomum species and found to be distinct in combinations of body shape, sucker ratio and shape of the gonads. Preliminary molecular data also demonstrate that they are distinct from each other and for those other species for which data are available.

  5. Record of Decision Remedial Alternative Selection for the C, F, K, and P-Area Coal Pile Runoff Basins (189-C, 289-F, 189-K, and 189-P)

    Energy Technology Data Exchange (ETDEWEB)

    Morgan, Randall

    1998-07-01

    The C-, F-, K-, and P-Area Coal Pile Runoff Basins (189-C, 289-F, 189-K, and 189-P) (C-, F-, K-, and P-CPRBs) waste units are listed as Resource Conservation and Recovery Act (RCRA) 3004(u) Solid Waste Management Units/Comprehensive Environmental Response, Compensation and Liability Act (CERCLA) units in Appendix C of the Federal Facility Agreement (FFA) for the Savannah River Site (SRS). The C-, F-, K-, and P-CPRBS comprise a single operable unit which was remediated under an early removal action during the summer of 1997. Slightly elevated levels of naturally occurring metals and radionuclides in the coal-laden sediments and shallow soils were confined to the 0-1 foot interval below the basin floor. These source materials were identified as low level threat wastes. Under the Removal Site Evaluation Report/Wastewater Closure Plan for the C-, F-, K-, and P-Area Coal Pile Runoff Basins (189-C, 289-F, 189-K, and 189-P) (U) (WSRC 1997b), the coal-laden sediments and shallow soils were removed from each of the four basins during the summer of 1997. At least four feet of clean backfill was placed in each basin to restore the area to the surrounding grade. This removal action completely freed the four CPRBS of the source material for the constituents of concern and the sulfide minerals, which were reducing the pH of the infiltrate. Because the source material has been removed from the CPRBs, releases of hazardous substances will not occur from this operable unit and there is no imminent or substantial endangerment to public health, welfare, or the environment.

  6. Contributions to our knowledge of the flora of Celebes (Coll. C. Monod de Froideville) and of some other Malaysian Islands

    NARCIS (Netherlands)

    Lam, H.J.

    1945-01-01

    The following notes are mainly based upon a small but interesting collection of plants, made in 1937—1939 by Mr C. Monod de Froideville, Civil Service Officer in the Netherlands Indies, during his extensive trips in the southern and central parts of the island of Celebes. His hobby was the study of

  7. F-4C/D Life Extension Program.

    Science.gov (United States)

    1982-10-01

    landing gear and consisted of a forward acting drag, simulating gear springback , and a vertical, upward acting load. Both loads were introduced at the gear...transducers used on each test cond~ition were logged on a Data System Check Sheet . Since the total number of transducers installed on the test article...TEAR BEAM ’ CAPCSR ’HI TN5 REAMOO FASENE IND R Of~ 68L 8?~4 CRACKU 0N1OAR PNA OIN TUEE OF3F46 T0HUNNLE’N ’R OP UE38-202-230REL AN ~a.MR.’ 3 RAKS N UE

  8. Contextualizing Next Generation Science Standards to Guide Climate Education in the U.S. Affiliated Pacific Islands (USAPI)

    Science.gov (United States)

    Sussman, A.; Fletcher, C. H.; Sachs, J. P.

    2012-12-01

    The USAPI has a population of about 1,800,000 people spread across 4.9 million square miles of the Pacific Ocean. The Pacific Islands are characterized by a multitude of indigenous cultures and languages. Many USAPI students live considerably below the poverty line. The Pacific Island region is projected to experience some of the most profound negative impacts of climate change considerably sooner than other regions. Funded by the National Science Foundation (NSF), the Pacific Islands Climate Education Partnership (PCEP) has developed a detailed strategic plan to collaboratively improve climate knowledge among the region's students and citizens in ways that exemplify modern science and indigenous environmental knowledge, address the urgency of climate change impacts, and honor indigenous cultures. Students and citizens within the region will have the knowledge and skills to advance understanding of climate change, and to adapt to its impacts. Core PCEP partners contribute expertise in climate science, the science of learning, the region's education infrastructure, and the region's cultures and indigenous knowledge and practices. PCEP's strategic education plan is guided by a general, multidisciplinary K-14 Climate Education Framework (CEF) that organizes fundamental science concepts and practices within appropriate grade-span progressions. This CEF is based largely upon the National Research Council's "A Framework for K-12 Science Education: Practices, Crosscutting Concepts, and Core Ideas" and the emerging Next Generation Science Standards. While the CEF is based upon these national Next Generation documents, it is also informed and strongly influenced by the region's geographic, climatic, cultural and socioeconomic contexts, notably indigenous knowledge and practices. Guided by the CEF, the PCEP in its initial development/planning phase has prototyped regional approaches to professional development, contextualizing curricula, and supporting community

  9. Measurement of $f(c \\to D^{*+} X)$, $f(b \\to D^{*+} X)$ and $\\Gamma_{c \\overline{c}}/\\Gamma_{had}$ using $D^{*\\pm}$ mesons

    CERN Document Server

    Ackerstaff, K.; Allison, John; Altekamp, N.; Anderson, K.J.; Anderson, S.; Arcelli, S.; Asai, S.; Axen, D.; Azuelos, G.; Ball, A.H.; Barberio, E.; Barillari, T.; Barlow, Roger J.; Bartoldus, R.; Batley, J.R.; Baumann, S.; Bechtluft, J.; Beeston, C.; Behnke, T.; Bell, A.N.; Bell, Kenneth Watson; Bella, G.; Bentvelsen, S.; Bethke, S.; Biebel, O.; Biguzzi, A.; Bird, S.D.; Blobel, V.; Bloodworth, I.J.; Bloomer, J.E.; Bobinski, M.; Bock, P.; Bonacorsi, D.; Boutemeur, M.; Bouwens, B.T.; Braibant, S.; Brigliadori, L.; Brown, Robert M.; Burckhart, H.J.; Burgard, C.; Burgin, R.; Capiluppi, P.; Carnegie, R.K.; Carter, A.A.; Carter, J.R.; Chang, C.Y.; Charlton, David G.; Chrisman, D.; Clarke, P.E.L.; Cohen, I.; Conboy, J.E.; Cooke, O.C.; Cuffiani, M.; Dado, S.; Dallapiccola, C.; Dallavalle, G.Marco; Davies, R.; De Jong, S.; del Pozo, L.A.; Desch, K.; Dienes, B.; Dixit, M.S.; do Couto e Silva, E.; Doucet, M.; Duchovni, E.; Duckeck, G.; Duerdoth, I.P.; Eatough, D.; Edwards, J.E.G.; Estabrooks, P.G.; Evans, H.G.; Evans, M.; Fabbri, F.; Fanti, M.; Faust, A.A.; Fiedler, F.; Fierro, M.; Fischer, H.M.; Fleck, I.; Folman, R.; Fong, D.G.; Foucher, M.; Furtjes, A.; Futyan, D.I.; Gagnon, P.; Gary, J.W.; Gascon, J.; Gascon-Shotkin, S.M.; Geddes, N.I.; Geich-Gimbel, C.; Geralis, T.; Giacomelli, G.; Giacomelli, P.; Giacomelli, R.; Gibson, V.; Gibson, W.R.; Gingrich, D.M.; Glenzinski, D.; Goldberg, J.; Goodrick, M.J.; Gorn, W.; Grandi, C.; Gross, E.; Grunhaus, J.; Gruwe, M.; Hajdu, C.; Hanson, G.G.; Hansroul, M.; Hapke, M.; Hargrove, C.K.; Hart, P.A.; Hartmann, C.; Hauschild, M.; Hawkes, C.M.; Hawkings, R.; Hemingway, R.J.; Herndon, M.; Herten, G.; Heuer, R.D.; Hildreth, M.D.; Hill, J.C.; Hillier, S.J.; Hobson, P.R.; Homer, R.J.; Honma, A.K.; Horvath, D.; Hossain, K.R.; Howard, R.; Huntemeyer, P.; Hutchcroft, D.E.; Igo-Kemenes, P.; Imrie, D.C.; Ingram, M.R.; Ishii, K.; Jawahery, A.; Jeffreys, P.W.; Jeremie, H.; Jimack, M.; Joly, A.; Jones, C.R.; Jones, G.; Jones, M.; Jost, U.; Jovanovic, P.; Junk, T.R.; Karlen, D.; Kartvelishvili, V.; Kawagoe, K.; Kawamoto, T.; Kayal, P.I.; Keeler, R.K.; Kellogg, R.G.; Kennedy, B.W.; Kirk, J.; Klier, A.; Kluth, S.; Kobayashi, T.; Kobel, M.; Koetke, D.S.; Kokott, T.P.; Kolrep, M.; Komamiya, S.; Kress, T.; Krieger, P.; von Krogh, J.; Kyberd, P.; Lafferty, G.D.; Lahmann, R.; Lai, W.P.; Lanske, D.; Lauber, J.; Lautenschlager, S.R.; Layter, J.G.; Lazic, D.; Lee, A.M.; Lefebvre, E.; Lellouch, D.; Letts, J.; Levinson, L.; Lloyd, S.L.; Loebinger, F.K.; Long, G.D.; Losty, M.J.; Ludwig, J.; Macchiolo, A.; Macpherson, A.; Mannelli, M.; Marcellini, S.; Markus, C.; Martin, A.J.; Martin, J.P.; Martinez, G.; Mashimo, T.; Mattig, Peter; McDonald, W.John; McKenna, J.; Mckigney, E.A.; McMahon, T.J.; McPherson, R.A.; Meijers, F.; Menke, S.; Merritt, F.S.; Mes, H.; Meyer, J.; Michelini, A.; Mikenberg, G.; Miller, D.J.; Mincer, A.; Mir, R.; Mohr, W.; Montanari, A.; Mori, T.; Morii, M.; Muller, U.; Mihara, S.; Nagai, K.; Nakamura, I.; Neal, H.A.; Nellen, B.; Nisius, R.; O'Neale, S.W.; Oakham, F.G.; Odorici, F.; Ogren, H.O.; Oh, A.; Oldershaw, N.J.; Oreglia, M.J.; Orito, S.; Palinkas, J.; Pasztor, G.; Pater, J.R.; Patrick, G.N.; Patt, J.; Pearce, M.J.; Perez-Ochoa, R.; Petzold, S.; Pfeifenschneider, P.; Pilcher, J.E.; Pinfold, J.; Plane, David E.; Poffenberger, P.; Poli, B.; Posthaus, A.; Rees, D.L.; Rigby, D.; Robertson, S.; Robins, S.A.; Rodning, N.; Roney, J.M.; Rooke, A.; Ros, E.; Rossi, A.M.; Routenburg, P.; Rozen, Y.; Runge, K.; Runolfsson, O.; Ruppel, U.; Rust, D.R.; Rylko, R.; Sachs, K.; Saeki, T.; Sarkisian, E.K.G.; Sbarra, C.; Schaile, A.D.; Schaile, O.; Scharf, F.; Scharff-Hansen, P.; Schenk, P.; Schieck, J.; Schleper, P.; Schmitt, B.; Schmitt, S.; Schoning, A.; Schroder, Matthias; Schultz-Coulon, H.C.; Schumacher, M.; Schwick, C.; Scott, W.G.; Shears, T.G.; Shen, B.C.; Shepherd-Themistocleous, C.H.; Sherwood, P.; Siroli, G.P.; Sittler, A.; Skillman, A.; Skuja, A.; Smith, A.M.; Snow, G.A.; Sobie, R.; Soldner-Rembold, S.; Springer, Robert Wayne; Sproston, M.; Stephens, K.; Steuerer, J.; Stockhausen, B.; Stoll, K.; Strom, David M.; Szymanski, P.; Tafirout, R.; Talbot, S.D.; Tanaka, S.; Taras, P.; Tarem, S.; Teuscher, R.; Thiergen, M.; Thomson, M.A.; von Torne, E.; Towers, S.; Trigger, I.; Trocsanyi, Z.; Tsur, E.; Turcot, A.S.; Turner-Watson, M.F.; Utzat, P.; Van Kooten, Rick J.; Verzocchi, M.; Vikas, P.; Vokurka, E.H.; Voss, H.; Wackerle, F.; Wagner, A.; Ward, C.P.; Ward, D.R.; Watkins, P.M.; Watson, A.T.; Watson, N.K.; Wells, P.S.; Wermes, N.; White, J.S.; Wilkens, B.; Wilson, G.W.; Wilson, J.A.; Wolf, G.; Wyatt, T.R.; Yamashita, S.; Yekutieli, G.; Zacek, V.; Zer-Zion, D.

    1998-01-01

    The production rates of D^*+/- mesons in charm and bottom events at centre-of-mass energies of about 91 GeV and the partial width of primary cc(bar) pairs in hadronic Z^0 decays have been measured at LEP using almost 4.4 million hadronic Z^0 decays collected with the OPAL detector between 1990 and 1995. Using a combination of several charm quark tagging methods based on fully and partially reconstructed D^*+/- mesons, and a bottom tag based on identified muons and electrons, the hadronisation fractions of charm and bottom quarks into D^*+/- mesons have been found to be: f(b -> D^*+ X) = 0.173 +/- 0.016 +/- 0.012 and f(c -> D^*+ X) = 0.222 +/- 0.014 +/- 0.014 The fraction of cc(bar) events in hadronic Z^0 decays, Gamma_cc(bar)/Gamma_had = Gamma(Z^0 -> cc(bar))/Gamma(Z^0 -> hadrons), is determined to be Gamma_cc(bar)/Gamma_had = 0.180 +/- 0.011 +/- 0.012 +/- 0.006 In all cases the first error is statistical, and the second one systematic. The last error quoted for Gamma_cc(bar)/Gamma_had is due to external bran...

  10. History of the Gas Turbine Engine in the United States: Bibliography

    Science.gov (United States)

    1988-05-11

    WRDC-TR-89-2062 HISTORY OF THE GAS TURBINE ENGINE IN THE __ UNITED STATES: BIBLIOGRAPHY James J. St.Peter D TIC Universal Energy Systems, Inc. F L £C...and to the Smithsonian’s National Air and Space Museum (NASM) in Washington, D.C. to talk to Rick Leyes , the Engine historian in their Aeronautical

  11. F2 slope as a Perceptual Cue for the Front-Back Contrast in Standard Southern British English.

    Science.gov (United States)

    Chládková, Kateřina; Hamann, Silke; Williams, Daniel; Hellmuth, Sam

    2017-09-01

    Acoustic studies of several languages indicate that second-formant (F2) slopes in high vowels have opposing directions (independent of consonantal context): front [iː]-like vowels are produced with a rising F2 slope, whereas back [uː]-like vowels are produced with a falling F2 slope. The present study first reports acoustic measurements that confirm this pattern for the English variety of Standard Southern British English (SSBE), where /uː/ has shifted from the back to the front area of the vowel space and is now realized with higher midpoint F2 values than several decades ago. Subsequently, we test whether the direction of F2 slope also serves as a reliable cue to the /iː/-/uː/ contrast in perception. The findings show that F2 slope direction is used as a cue (additional to midpoint formant values) to distinguish /iː/ from /uː/ by both young and older Standard Southern British English listeners: an otherwise ambiguous token is identified as /iː/ if it has a rising F2 slope and as /uː/ if it has a falling F2 slope. Furthermore, our results indicate that listeners generalize their reliance on F2 slope to other contrasts, namely /ɛ/-/ɒ/ and /æ/-/ɒ/, even though F2 slope is not employed to differentiate these vowels in production. This suggests that in Standard Southern British English, a rising F2 seems to be perceptually associated with an abstract feature such as [+front], whereas a falling F2 with an abstract feature such as [-front].

  12. Absolute Potentials of Standard Reference Electrodes at 25 C

    OpenAIRE

    Raji Heyrovska

    2010-01-01

    Aqueous standard redox potentials are conventionally referred to that of the standard hydrogen electrode (SHE) as zero (IUPAC definition), in the absence of the knowledge of its absolute value. Recently, the author obtained its value (4.20 V) from a newly found linear dependence of redox potentials on ionization potentials. This has enabled now to express the potentials of standard reference electrodes in terms of the absolute values.

  13. Clinical standardized fMRI reveals altered language lateralization in patients with brain tumor.

    Science.gov (United States)

    Partovi, S; Jacobi, B; Rapps, N; Zipp, L; Karimi, S; Rengier, F; Lyo, J K; Stippich, C

    2012-12-01

    Brain tumors affecting language-relevant areas may influence language lateralization. The purpose of this study was to systematically investigate language lateralization in brain tumor patients using clinical language fMRI, comparing the results with a group of healthy volunteers. Fifty-seven strictly right-handed patients with left-hemispheric-space intracranial masses (mainly neoplastic) affecting either the Broca area (n = 19) or Wernicke area (n = 38) were prospectively enrolled in this study. Fourteen healthy volunteers served as a control group. Standardized clinical language fMRI, using visually triggered sentence- and word-generation paradigms, was performed on a 1.5T MR scanner. Semiautomated analyses of all functional data were conducted on an individual basis using BrainVoyager. A regional lateralization index was calculated for Broca and Wernicke areas separately versus their corresponding right-hemisphere homologs. In masses affecting the Broca area, a significant decrease in the lateralization index was found when performing word generation (P = .0017), whereas when applying sentence generation, the decrease did not reach statistical significance (P = .851). Masses affecting the Wernicke area induced a significant decrease of the lateralization index when performing sentence generation (P = .0007), whereas when applying word generation, the decrease was not statistically significant (P = .310). Clinical language fMRI was feasible for patients with brain tumors and provided relevant presurgical information by localizing essential language areas and determining language dominance. A significant effect of the brain masses on language lateralization was observed, with a shift toward the contralesional, nondominant hemisphere. This may reflect compensatory mechanisms of the brain to maintain communicative abilities.

  14. Early Successes in an Open Access, Provincially Funded Hepatitis C Treatment Program in Prince Edward Island.

    Science.gov (United States)

    Smyth, Daniel; Francheville, Jordan W; Rankin, Robin; Beck, Jeremy; Hoare, Connie; Materniak, Stefanie; German, Greg; Barrett, Lisa; Bunimov-Wall, Natalie

    2017-01-01

    The availability of curative hepatitis C therapies has created an opportunity to improve delivery and access. Local providers, government, industry, and community groups in Prince Edward Island developed an innovative province-wide care model. Our goal was to describe the first year of program implementation. Using a community based prospective observational study design, all chronic hepatitis C referrals received from April 2015 to April 2016 were recorded in a database. Primary analysis assessed the time from referral to assessment/treatment, as well as the number of referrals, assessments, and treatment initiations. Secondary objectives included: 1) Treatment effectiveness using intention-to-treat analysis; and 2) Patient treatment experience assessed using demographics, adverse events, and medication adherence. During the study period 242 referrals were received, 123 patients were seen for intake assessments, and 93 initiated direct-acting antiviral therapy based on medical need. This is compared to 4 treatment initiations in the previous 2 years. The median time from assessment to treatment initiation was 3 weeks. Eighty-two of 84 (97.6%, 95% CI 91.7 - 99.7%) patients for whom outcome data were available achieved sustained virologic response at 12 weeks post-treatment; 1 was lost to follow-up and 1 died from an unrelated event. In the voluntary registry, 39.7% of patients reported missed treatment doses. In conclusion, results from the first 12 months of this multi-phase hepatitis C elimination strategy demonstrate improved access to treatment, and high rates of safe engagement and cure for patients living with chronic hepatitis C genotype 1 infections.

  15. Non-Standard (Flag-dipoles) Spinor Fields in f(R) Cosmology

    CERN Document Server

    da Rocha, Roldao; da Silva, J M Hoff; Cavalcanti, R T; Silva-Neto, J A

    2013-01-01

    The Dirac equation in a f(R) Riemann-Cartan cosmological scenario admits solutions, that are shown here not to be Dirac spinor fields, which seems to play a fundamental role on the matter fields properties in such cosmological framework, as: a) spinor fields in torsional f(R) or conformal gravity, that satisfy the Dirac equation, correspond to non-standard, flagpole, spinor fields (in both Lounesto and Wigner classification); b) the field equations imply a constraint among the bilinear covariants associated to the spinor field. Some constraints imposed on the metric and/or on the spinor field imply that an isotropic universe with matter fields circumvent the question that Dirac fields do not undergo the cosmological principle. Remarkably, if the spinor fields are assumed to satisfy the Dirac equation, they are shown not to be legitimate Dirac spinor fields, under Lounesto spinor field classification, but indeed flag-dipole singular spinor fields. Such type of spinor fields can still be led to flagpole spinor ...

  16. Revisiting Comets C/2012 F6 (Lemmon) and C/2012 S1 (ISON) with ALMA Autocorrelations

    Science.gov (United States)

    Yukiko Palmer, Maureen; Cordiner, Martin; de Val-Borro, Miguel; Charnley, Steven B.; Mumma, Michael J.

    2017-10-01

    The Atacama Large Millimeter/submillimeter array (ALMA) is a powerful tool for high-resolution mapping, but as an interferometer it is insensitive to large-scale structures due to the lack of zero-spacing (autocorrelation/single-dish) measurements. This is especially limiting in studies of cometary comae, which can extend up to hundreds of arcseconds. In this work, we make use of ALMA autocorrelations, treating the entire ALMA array as a collection of single-dish telescopes, to study the large comae of comets C/2012 F6 (Lemmon) and C/2012 S1 (ISON). This has significantly improved our spectral line sensitivity, allowing for the detection of new molecules in ISON's coma, including HCO+ and H(13C)N. We also present results from the combined use of ALMA autocorrelation (single dish) and cross-correlation (interferometric) data to create a more complete picture of the coma gas distribution in Lemmon. Since its initial detection in Hyakutake (Irvine et al. 1996), the origins of cometary HNC have been under investigation (Irvine et al. 1998; Rodgers & Charnley 2001, 2005; Lis et al. 2008). It might be produced from the degradation of a solid organic material. More measurements of the HNC parent scale length are needed to help understand the source of HNC. Using ALMA autocorrelation data, we follow up on the detection of HNC in comet Lemmon by Cordiner et al. (2014) and, assisted by newly-developed radiative transfer/excitation models, provide an analysis of its distribution in this comet.References: Irvine, W. M., Bockelee-Morvan, D., Lis, D. C., et al. 1996, Nature, 383, 418Irvine, W. M., Bergin, E. A., Dickens, J. E., et al. 1998, Nature, 393, 547; Rodgers, S. D., & Charnley, S. B. 2001, MNRAS, 323, 84; ---. 2005, MNRAS, 356, 1542; Lis, D. C., Bockelee-Morvan, D., Boissier, J., et al. 2008, ApJ, 675, 931; Cordiner, M. A., Remijan, A. J., Boissier, J., et al. 2014, ApJL, 792, L2Acknowledgments: NASA’s Astrobiology Program supported this work through the Goddard Center

  17. Appointing silver and bronze standards for noncovalent interactions: A comparison of spin-component-scaled (SCS), explicitly correlated (F12), and specialized wavefunction approaches

    Science.gov (United States)

    Burns, Lori A.; Marshall, Michael S.; Sherrill, C. David

    2014-12-01

    A systematic examination of noncovalent interactions as modeled by wavefunction theory is presented in comparison to gold-standard quality benchmarks available for 345 interaction energies of 49 bimolecular complexes. Quantum chemical techniques examined include spin-component-scaling (SCS) variations on second-order perturbation theory (MP2) [SCS, SCS(N), SCS(MI)] and coupled cluster singles and doubles (CCSD) [SCS, SCS(MI)]; also, method combinations designed to improve dispersion contacts [DW-MP2, MP2C, MP2.5, DW-CCSD(T)-F12]; where available, explicitly correlated (F12) counterparts are also considered. Dunning basis sets augmented by diffuse functions are employed for all accessible ζ-levels; truncations of the diffuse space are also considered. After examination of both accuracy and performance for 394 model chemistries, SCS(MI)-MP2/cc-pVQZ can be recommended for general use, having good accuracy at low cost and no ill-effects such as imbalance between hydrogen-bonding and dispersion-dominated systems or non-parallelity across dissociation curves. Moreover, when benchmarking accuracy is desirable but gold-standard computations are unaffordable, this work recommends silver-standard [DW-CCSD(T**)-F12/aug-cc-pVDZ] and bronze-standard [MP2C-F12/aug-cc-pVDZ] model chemistries, which support accuracies of 0.05 and 0.16 kcal/mol and efficiencies of 97.3 and 5.5 h for adenine.thymine, respectively. Choice comparisons of wavefunction results with the best symmetry-adapted perturbation theory [T. M. Parker, L. A. Burns, R. M. Parrish, A. G. Ryno, and C. D. Sherrill, J. Chem. Phys. 140, 094106 (2014)] and density functional theory [L. A. Burns, Á. Vázquez-Mayagoitia, B. G. Sumpter, and C. D. Sherrill, J. Chem. Phys. 134, 084107 (2011)] methods previously studied for these databases are provided for readers' guidance.

  18. Mechanism of C-F reductive elimination from palladium(IV) fluorides.

    Science.gov (United States)

    Furuya, Takeru; Benitez, Diego; Tkatchouk, Ekaterina; Strom, Alexandra E; Tang, Pingping; Goddard, William A; Ritter, Tobias

    2010-03-24

    The first systematic mechanism study of C-F reductive elimination from a transition metal complex is described. C-F bond formation from three different Pd(IV) fluoride complexes was mechanistically evaluated. The experimental data suggest that reductive elimination occurs from cationic Pd(IV) fluoride complexes via a dissociative mechanism. The ancillary pyridyl-sulfonamide ligand plays a crucial role for C-F reductive elimination, likely due to a kappa(3) coordination mode, in which an oxygen atom of the sulfonyl group coordinates to Pd. The pyridyl-sulfonamide can support Pd(IV) and has the appropriate geometry and electronic structure to induce reductive elimination.

  19. Studies of Mini-Turbines

    Science.gov (United States)

    Chan, Stacey; Endo, Masaki; Romanko, Michael; Williamson, Chk

    2013-11-01

    Urban environments are inaccessible to large wind turbines of the classical ``windmill'' design. By exploring small-scale vertical-axis wind turbines (VAWTs), wind energy can possibly be harvested from the constrained spaces within cities. We present a comprehensive study of blade offset pitch angle and relative blade size (ratio of blade chordlength/turbine diameter, c/D). We find that the optimal pitch angle for a symmetric blade is the angle at which the midpoint chordline is tangent to the turbine circumference. Also, a turbine with conventional blades of small c/D ratio (c/D = 0.12) - typical of large scale turbines - do not operate well at low Reynolds numbers. On the other hand, the maximum coefficient of power for turbines with larger c/D ratio (c/D = 0.36) is much higher than for the conventional small-blades. As blade size increases, the operating range of TSR (Tip Speed Ratio) also increases, making large-chord turbines more robust to the prevailing wind conditions. Surprisingly, the regime of TSR for maximum power extracted, at these low Reynolds numbers, corresponds with small or even negative power predictions, based on streamtube theory.

  20. Wind characterization for design and comparison with standards, an example from Lyse at the Swedish west coast

    Energy Technology Data Exchange (ETDEWEB)

    Ganander, H. [Teknikgruppen AB, Sollentuna (Sweden); Carlen, I. [Chalmers Univ. of Technology, Goeteborg (Sweden). Div. of Building Technology; Bergstroem, H. [Uppsala Univ. (Sweden). Dept. of Meteorology

    1996-12-01

    The Lyse site at the Swedish west coast is an area with an archipelago of rocky islands to the west and an equally rocky mainland to the east. In between there are some open sea areas. As being the responsible project manager for the erection and the operation of a turbine at a site like Lyse, the question arises about characterization of the wind for design or purchase of a wind turbine. Or in other words what wind turbine class has to be used for the design, according to existing standards like for example IEC-1400 ? 3 refs, 10 figs

  1. Double Insertion of Coordinated Phosphanylalkyne Ligands into a Pt-C(6)F(5) Bond.

    Science.gov (United States)

    Charmant; Forniés; Gómez; Lalinde; Moreno; Orpen; Solano

    1999-10-18

    Enhanced reactivity is shown by uncoordinated C identical withC bonds in the proximity of a metal in phosphanylacetylene complexes. cis-[Pt(C(6)F(5))(2)(thf)(2)] reacts with [M(C(6)F(5))(2)(PPh(2)C identical withCPh)(2)] (M=Pt, Pd) to form binuclear complexes containing the novel 2,3-bis(diphenylphosphanyl)-1,3-butadien-1-yl bridging ligand. Substitution of the solvent ligands with, for example, PPh(2)H (see picture) provides species that could be characterized by X-ray crystallography.

  2. Utilising Sodium-Mediated Ferration for Regioselective Functionalisation of Fluoroarenes via C-H and C-F Bond Activations.

    Science.gov (United States)

    Hevia, Eva; Maddock, Lewis C H; Nixon, Tracy; Kennedy, Alan R; Probert, Michael R; Clegg, William

    2017-10-25

    While Fe(II) complexes have shown little promise in deprotonative metallation chemistry, pairing iron bis(amide) Fe(HMDS)2 with Na(HMDS) to form new sodium ferrate base [(dioxane)0.5·NaFe(HMDS)3] (1) enables regioselective mono and di-ferration (via direct Fe-H exchange) of a wide range of fluoroaromatic substrates under mild reaction conditions. Trapping of several ferrated intermediates has provided key insight into how synchronised Na/Fe cooperation operates in these transformations. Furthermore using excess 1 at 80oC switches on a remarkable cascade process inducing the collective 2-fold C-H/3-fold C-F bond activation, where each C-H bond is transformed to C-Fe bonds whereas each C-F bond is transformed into a C-N bond. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  3. Interaction between lattice dislocations and grain boundaries in f.c.c. and ordered compounds : a computer simulation

    NARCIS (Netherlands)

    Pestman, B.J.; Hosson, J.Th.M. De; Vitek, V.; Schapink, F.W.

    1991-01-01

    The interaction of 1/2<110> screw- and 60° dislocations with symmetric [110] tilt boundaries was investigated by atomistic simulations using many-body potentials representing a pure f.c.c. metal and ordered intermetallic compounds. The calculations were performed with and without an applied shear

  4. 11kW Stand Alone Wind Turbine Based on Proven Wind Turbine

    DEFF Research Database (Denmark)

    Bindner, Henrik; Wodstrup, Jens; Andersen, Jesper

    2004-01-01

    The paper will present the rationale behind the design of a stand-alone version of a existing 11kW wind turbine that has been installed at 100 sites mainly in Denmark. The wind turbine has been developed as a part of the Danish household wind turbine programme that included certification......, and a measurement programme. The positive operational experience with the turbine has motivated the development of a stand-alone version. The stand-alone version uses the standard version of the wind turbine combined with a back-to-back converter arrangement in order to decouple the wind turbine from the grid...

  5. [Hepatitis C virus F protein-mediated inhibition of hepatoma cell proliferation].

    Science.gov (United States)

    Zhou, Fan; Liu, Jiao; Chen, Qing-mei; Shan, Xiao-ling; Chen, Lin-lin; Quan, Hui-qin; Tang, Ni

    2012-05-01

    To investigate the biological function of the hepatitis C virus (HCV)-encoded F protein in hepatocytes. The full-length F gene was amplified by PCR from HCV genotype 1a and cloned into plasmid pSEB-3Flag by restriction enzyme digestion and ligation. Hepatoma cell lines, Huh7 and SMMC7721, were transfected with the resultant recombinant pSEB-3Flag-F or the original pSEB-3Flag (negative control) and screened with the selective antibiotic, blasticidin. Stable F gene and protein expression was verified by RT-PCR analysis. Analysis of cell growth and cell cycle was carried out by MTS assay, crystal violet staining and flow cytometry. Huh7 and SMMC7721 cells transfected with pSEB-3Flag-F plasmid (Huh7-F and SMMC7721-F, respectively) uniquely expressed the F gene and protein. The Huh7-F and SMMC7721-F cells showed significantly decreased proliferation rates, compared to the respective control groups. A similar HCV F-mediated growth-inhibiting activity was observed by the cell viability assay. Furthermore, cell cycle analysis revealed that the S-phase distribution was much lower in Huh7-F (47.12%) and SMMC7721-F (30.75%) cells than in the respective controls (55.35% and 33.23%, respectively) (P less than 0.05). Stable expression of the HCV F gene reduced the in vitro proliferation rate of hepatoma cell lines, indicating that the F protein may function as a growth inhibitor of infected cells.

  6. Investigating Effects of Resolution on Landslide Identification and Landscape Attributes in the Queen Charlotte Islands, B.C.

    Science.gov (United States)

    Sjogren, D.; Martin, Y.

    2003-12-01

    Two exceptional mass wasting inventories (Rood, 1984; Gimbarzevsky, 1988) have been collected and analyzed for the Queen Charlotte Islands, British Columbia. These islands are located about 80 km off the coast of British Columbia, have a mild, wet climate and are seismically active. These factors contribute to a high frequency of landsliding. The Gimbarzevsky database consists of about 8000 debris slides, debris avalanches and debris flows over the entire 10,000 km2 of the Queen Charlotte Islands. Events were identified from 1:50,000 panchromatic aerial photographs. Large grid cells (1 km2) were used to classify landslide attributes, such as gradient and aspect. The Rood database consists of about a thousand events covering a total area of 350 km2 in both logged and unlogged terrain. Failures were identified from 1:11,000 and 1:13,000 aerial photographs. Terrain attributes, such as initiation gradient, were obtained using photogrammetric techniques. The present study explores the effects of topographic data (DEM) resolution and air photo resolution on landsliding analysis. For the former, landscape attributes associated with mass movements, such as initiation gradient and aspect, are compared for the original Gimbarzevsky results (based on 1-km grid cells) and new results for this database derived from 100-m DEM data. For the latter, we explore the effects of aerial photograph scale on landslide identification for the Rood and Gimbarzevsky databases. In addition, we explore the benefits in deriving initiation gradients from detailed, yet time-consuming, photogrammetric techniques versus more automated approaches using existing DEM data. References: Gimbarzevsky, P. (1988) Mass Wasting on the Queen Charlotte Islands: A Regional Inventory, B.C. Ministry of Forests, Land Management Report 29; Rood, K. (1984) An Aerial Photograph Inventory of the Frequency and Yield of Mass Wasting on the Queen Charlotte Islands, B.C., B.C. Ministry of Forests, Land Management Report

  7. IPCC IS92 Emissions Scenarios (A, B, C, D, E, F) Dataset Version 1.1

    Data.gov (United States)

    National Aeronautics and Space Administration — The Intergovernmental Panel on Climate Change (IPCC) IS92 Emissions Scenarios (A, B, C, D, E, F) Dataset Version 1.1 consists of six global and regional greenhouse...

  8. Thermosyphon Method for Cooling the Rotor Blades of High-Temperature Steam Turbines

    Directory of Open Access Journals (Sweden)

    Bogomolov Alexander R.

    2016-01-01

    Full Text Available The design scheme of closed two-phase thermosyphon were suggested that can provide standard thermal operation of blades of high-temperature steam turbine. The method for thermosyphon calculation is developed. The example of thermal calculation was implemented, it showed that to cool the steam turbine blades at their heating by high-temperature steam, the heat can be removed in the rear part of the blades by air with the temperature of about 440°C.

  9. DO-178C: A New Standard for Software Safety Certification

    Science.gov (United States)

    2010-04-26

    European Headquarters: 46 rue d’Amsterdam 75009 Paris France +33-1-4970-6716 (voice) +33-1-4970-0552 (FAX) www.adacore.com Ben Brosgol brosgol...Great Britain, France , Germany, Sweden • Some participation from Brazil and recently China Th i ki d f i ti t dree ma n n s o organ za ons represen e...Airframe industry and contractors (Boeing, Airbus, Lockheed, Rockwell Collins, Honeywell, Thales, Eurocopter , …) • Government agencies

  10. Turbine system

    Science.gov (United States)

    McMahan, Kevin Weston; Dillard, Daniel Jackson

    2016-05-03

    A turbine system is disclosed. The turbine system includes a transition duct having an inlet, an outlet, and a passage extending between the inlet and the outlet and defining a longitudinal axis, a radial axis, and a tangential axis. The outlet of the transition duct is offset from the inlet along the longitudinal axis and the tangential axis. The turbine system further includes a turbine section connected to the transition duct. The turbine section includes a plurality of shroud blocks at least partially defining a hot gas path, a plurality of buckets at least partially disposed in the hot gas path, and a plurality of nozzles at least partially disposed in the hot gas path. At least one of a shroud block, a bucket, or a nozzle includes means for withstanding high temperatures.

  11. 1H, 13C and 19F NMR studies on fluorinated ethers

    Science.gov (United States)

    Balonga, P. E.; Kowalewski, V. J.; Contreras, R. H.

    The enflurane and ethoxyflurane 1H, 13C and 19F NMR spectra are examined—including sign determination of FF and FH couplings—and considered in the light of previously reported results for methoxyflurane. Conformational differences between methoxyflurane and the former two molecules are indicated by through space FH coupling constants and by the nonequivalence of geminal fluorine nuclei. Populations of conformers about the CC bond are estimated.

  12. Bygningshistoriske undersøgelser af udvalgte bygninger af C.F. Hansen

    DEFF Research Database (Denmark)

    Larsen, Lene Gerd

    2002-01-01

    Bidrag til forskningsprojektet "Historiske mørtler", 1800-tallets byggeri med særlig vægt på C.F. Hansen. En bygningsarkivalsk undersøgelse af C.F. Hansens råd- og domhus i København. Undersøgelsen dokumenterer de bygningsistandsættelser og -forandringer der er gennemført i årene 1815-1870...

  13. 46 CFR 154.615 - Design temperature below 0 °C (32 °F) and down to −55 °C (−67 °F).

    Science.gov (United States)

    2010-10-01

    ... LIQUEFIED GASES Design, Construction and Equipment Materials § 154.615 Design temperature below 0 °C (32 °F... 46 Shipping 5 2010-10-01 2010-10-01 false Design temperature below 0 °C (32 °F) and down to â55... tanks and secondary barriers for a design temperature below 0 °C (32 °F) and down to −55 °C (−67 °F...

  14. LM6000 gas turbine plant; LM6000 gas turbine plant

    Energy Technology Data Exchange (ETDEWEB)

    Nozaki, N.; Sato, T. [Ishikawajima-Harima Heavy Industries Co. Ltd., Tokyo (Japan)

    1998-09-01

    The LM6000 gas turbine is a most advanced industrial gas turbine derived from an aero-engine. The gas turbine has a power output of 45 MW with over 42% thermal efficiency, and such features as high efficiency, compactness, and easy maintenance. The gas turbine is used widely for electric power generation, marine propulsion and mechanical drive applications, particularly frequently for medium-capacity power plants because of its high efficiency. This paper summarizes the newest form of this LM6000 gas turbine, and introduces as its application example to power plants two examples of practical use in combined cycle power generation which is anticipated of increased use in the future. A combined cycle power plant for a paper mill in Indonesia is characterized by the gas turbine being a back-pressure turbine, where low pressure steam after having been used for power generation is fed to the paper mill. A combined cycle power plant for the Xinzhu scientific and industrial complex in Taiwan is characterized by adoption of a sucked air cooling device, which cools gas turbine sucked air temperature down to 7.2 deg C, and the gas turbine power generator being operated upto its maximum output of 45 MW. 7 figs., 1 tab.

  15. F1 hybrids of BALB/c and C57BL/6 mouse strains respond differently ...

    Indian Academy of Sciences (India)

    The two F1 hybrids showed drastic differences in their gene expression profiles to ionizing radiation exposure particularly in case of the genes involved in DNA ... trait alleles from the parents to F1 progeny which is dependent on the sex of the parent mouse strain used to set up the crosses and other environmental factors.

  16. Wind Turbine Generator System Safety and Function Test Report for the Ventera VT10 Wind Turbine

    Energy Technology Data Exchange (ETDEWEB)

    Smith, J.; Huskey, A.; Jager, D.; Hur, J.

    2012-11-01

    This report summarizes the results of a safety and function test that NREL conducted on the Ventera VT10 wind turbine. This test was conducted in accordance with the International Electrotechnical Commissions' (IEC) standard, Wind Turbine Generator System Part 2: Design requirements for small wind turbines, IEC 61400-2 Ed.2.0, 2006-03.

  17. Wind Turbine Generator System Safety and Function Test Report for the Entegrity EW50 Wind Turbine

    Energy Technology Data Exchange (ETDEWEB)

    Smith, J.; Huskey, A.; Jager, D.; Hur, J.

    2012-11-01

    This report summarizes the results of a safety and function test that NREL conducted on the Entegrity EW50 wind turbine. This test was conducted in accordance with the International Electrotechnical Commissions' (IEC) standard, Wind Turbine Generator System Part 2: Design requirements for small wind turbines, IEC 61400-2 Ed.2.0, 2006-03.

  18. C-CAP Big Island, Hawaii 2005-2010 Land Cover Change Analysis

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set contains the 2005 and 2010 classifications of Big Island and can be used to analyze change. This data set utilized utilized 7 full or partial...

  19. Future needs and requirements for AMS C-14 standards and reference materials

    NARCIS (Netherlands)

    Scott, EM; Boaretto, E; Bryant, C; Cook, GT; Gulliksen, S; Harkness, DD; Heinemeier, J; McGee, E; Naysmith, P; Possnert, G; van der Plicht, H; van Strydonck, M; Cook, Gordon T.

    C-14 measurement uses a number of standards and reference materials with different properties. Historically the absolute calibration of C-14 measurement was tied to 1890 wood, through the 'primary' standard of NBS-OxI (produced by the National Bureau of Standards, now NIST - National Institute of

  20. A 19F NMR study of C-I....pi- halogen bonding

    DEFF Research Database (Denmark)

    Hauchecorne, Dieter; vand er Veken, Benjamin J.; Herrebout, Wouter A.

    2011-01-01

    The formation of halogen bonded complexes between toluene-d8 and the perfluoroiodopropanes 1-C3F7I and 2-C3F7I has been investigated using 19F NMR spectroscopy. For both Lewis acids, evidence was found for the formation of a C–I⋯π halogen bonded complex. The complex formed is a 1:1 type. Using...... results are supported by ab initio calculations at the B3LYP-PCM/6-311++G(d,p) + LanL2DZ∗ level....

  1. Industrial Advanced Turbine Systems Program overview

    Energy Technology Data Exchange (ETDEWEB)

    Esbeck, D.W. [Solar Turbines Inc., San Diego, CA (United States)

    1995-10-01

    The U.S. Department of Energy (DOE), in partnership with industry, has set new performance standards for industrial gas turbines through the creation of the Industrial Advanced Turbine System Program. Their leadership will lead to the development of an optimized, energy efficient, and environmentally friendly gas turbine power systems in this size class (3-to-20 MW). The DOE has already created a positive effect by encouraging gas turbine system manufacturers to reassess their product and technology plans using the new higher standards as the benchmark. Solar Turbines has been a leader in the industrial gas turbine business, and is delighted to have joined with the DOE in developing the goals and vision for this program. We welcome the opportunity to help the national goals of energy conservation and environmental enhancement. The results of this program should lead to the U.S. based gas turbine industry maintaining its international leadership and the creation of highly paid domestic jobs.

  2. Albert Einstein and Wernher von Braun - the two great German-American physicists seen in a historical perspective.

    Science.gov (United States)

    Winterberg, Friedwardt

    2008-04-01

    It was Albert Einstein who for the first time changed our view of the universe to be a non-euclidean curved space-time. And it was Wernher von Braun who blazed the trail to take us into this universe, leaving for the first time the gravitational field of our planet earth, with the landing a man on the moon the greatest event in human history. Both these great physicists did this on the shoulders of giants. Albert Einstein on the shoulders of his landsman, the mathematician Bernhard Riemann, and Wernher von Braun on the shoulders of Goddard and Oberth. Both Einstein and von Braun made a Faustian pact with the devil, von Braun by accepting research funds from Hitler, and Einstein by urging Roosvelt to build the atom bomb (against Hitler). Both of these great men later regretted the use of their work for the killing of innocent bystanders, even though in the end the invention of nuclear energy and space flight is for the benefit of man. Their example serves as a warning for all of us. It can be formulated as follows: ``Can I in good conscience accept research funds from the military to advance scientific knowledge, for weapons developed against an abstract enemy I never have met in person?'' Weapons if used do not differentiate between the scientist, who invented these weapons, and the non-scientist.

  3. A Low Cost C8051F006 SoC-Based Quasi-Static C-V Meter for Characterizing Semiconductor Devices

    Directory of Open Access Journals (Sweden)

    Khairurrijal Khairurrijal

    2012-12-01

    Full Text Available Based on a C8051F006 SoC (system on-a-chip, a simple and low cost quasi-static capacitance-voltage (C-V meter was designed and developed to obtain C-V characteristics of semiconductor devices. The developed C-V meter consists of a capacitance meter, a programmable voltage source, a C8051F006 SoC-based slave controller, and a personal computer (PC as a master controller. The communication between the master and slave controllers is facilitated by the RS 232 serial communication. The accuracy of the C-V meter was guaranteed by the calibration functions, which are employed by the program in the PC and obtained through the calibration processes of analog to digital converter (ADC, digital to analog converters (DACs of the C8051F006 SoC, and the programmable voltage source. Examining 33-pF and 1000-pF capacitors as well three different p-n junction diodes, it was found that the capacitances of common capacitors are in the range of specified values and typical C-V curves of p-n junction diodes are achieved.

  4. Offshore Wind Turbine Design

    DEFF Research Database (Denmark)

    Frandsen, Sten; Hansen, Erik Asp; Ibsen, Lars Bo

    2006-01-01

    Current offshore wind turbine design methods have matured to a 1st generation state, manifested in the draft of a possible standard, IEC 61400-3 (2005). It is now time to investigate the possibilities of improving existing methods. To do so in an efficient manner a clear identification of the most...... important uncertainty drivers specific for offshore wind turbine design loads is required. Describing the initial efforts in a Danish research project, the paper points to focal points for research and development. These are mainly: soil-structure interaction, improved modelling of wave loads from deep...

  5. Uso de C3F8 no descolamento da membrana de Descemet pós-facectomia C3F8 use in Descemet detachment after cataract surgery

    Directory of Open Access Journals (Sweden)

    Abrahão da Rocha Lucena

    2006-06-01

    Full Text Available INTRODUÇÃO: O descolamento da membrana de Descemet é complicação rara, mas devastadora após facectomia. Algumas alternativas têm sido usadas para reposição da Descemet: bolha de ar, sutura com transfixação da córnea, viscoelástico associado com bolha de ar e gás SF6 ou C3F8. O transplante de córnea é o último recurso utilizado. OBJETIVO: Avaliar os resultados anatômicos e funcionais, do descolamento iatrogênico da membrana de Descemet, com uso de C3F8 (16% na câmara anterior em seis olhos pós-facectomia. MÉTODOS: Após colocação de 0,5 ml do gás em câmara anterior avaliou-se localização justa-estromal da membrana de Descemet em lâmpada de fenda. Os olhos com deslocamento superior/central eram orientados a ficar em decúbito elevado por dois dias e no caso do deslocamento inferior solicitamos decúbito dorsal com leve supraversão. RESULTADOS: A média de idade foi de 71,3 ± 9,3 anos, sendo quatro do sexo feminino e dois do sexo masculino. Todos os olhos tiveram sucesso com a colocação do C3F8, havendo aumento da pressão intra-ocular em um caso. O edema corneano regrediu a partir do segundo dia com resolução completa até o quarto dia. A acuidade visual melhorou em todos os casos logo após regressão do edema, sendo reavaliada quarenta e cinco dias depois. CONCLUSÃO: A introdução unicamente do gás C3F8 não expansivo para colar a membrana de Descemet é citado pela primeira vez na literatura brasileira. O restabelecimento da acuidade visual é rápida, o método é seguro, efetivo e de fácil execução, sendo realizado sob anestesia tópica.INTRODUCTION: Descemet's membrane detachment is a rare but serious complication following cataract surgery. Extensive detachments that affect the visual axis may result in poor vision and require penetrating corneal grafts. Some alternatives have been used to reattach Descemet's membrane: air bubble, transcorneal sutures and intracameral viscoelastic gel plus SF6 or C3F

  6. 26 CFR 5c.168(f)(8)-7 - Reporting of income, deductions and investment tax credit; at risk rules.

    Science.gov (United States)

    2010-04-01

    ... tax credit; at risk rules. 5c.168(f)(8)-7 Section 5c.168(f)(8)-7 Internal Revenue INTERNAL REVENUE... UNDER THE ECONOMIC RECOVERY TAX ACT OF 1981 § 5c.168(f)(8)-7 Reporting of income, deductions and... has the option to sell the property to X for $2,160,000. Under § 5c.168(f)(8)-7(d), the aggregate...

  7. E2F repression by C/EBPalpha is required for adipogenesis and granulopoiesis in vivo

    DEFF Research Database (Denmark)

    Porse, B T; Pedersen TA; Xu, X

    2001-01-01

    differentiation in vivo. These results indicate that E2F repression by C/EBPalpha is critical for its ability to induce terminal differentiation, and thus provide genetic evidence that direct cell cycle control by a mammalian lineage-instructive transcription factor couples cellular growth arrest......The C/EBPalpha transcription factor is required for differentiation of adipocytes and neutrophil granulocytes, and controls cellular proliferation in vivo. To address the molecular mechanisms of C/EBPalpha action, we have identified C/EBPalpha mutants defective in repression of E2F......-dependent transcription and found them to be impaired in their ability to suppress cellular proliferation, and to induce adipocyte differentiation in vitro. Using targeted mutagenesis of the mouse germline, we show that E2F repression-deficient C/EBPalpha alleles failed to support adipocyte and granulocyte...

  8. Cold Reversal on Kodiak Island, Alaska, Correlated with the European Younger Dryas by Using Variations of Atmospheric C-14 Content

    Science.gov (United States)

    Hajdas, Irka; Bonani, Georges; Boden, Per; Peteet, Dorothy M.; Mann, Daniel H.

    1999-01-01

    High-resolution AMS (accelerator-mass-spectrometer) radiocarbon dating was performed on late-glacial macrofossils in lake sediments from Kodiak Island, Alaska, and on shells in marine sediments from southwest Sweden. In both records, a dramatic drop in radiocarbon ages equivalent to a rise in the atmospheric C-14 by approximately 70%. coincides with the beginning of the cold period at 11000 yr B.P. (C-14 age). Thus our results show that a close correlation between climatic records around the globe is possible by using a global signature of changes in atmospheric C-14 content.

  9. Trace elements (Cu, Zn, and Hg) and δ13C/δ15N in seabird subfossils from three islands of the South China Sea and its implications.

    Science.gov (United States)

    Xu, Liqiang; Liu, Xiaodong; Nie, Yaguang

    2016-05-01

    Seabird subfossils were collected on three islands of the Xisha Archipelago, South China Sea. Via elemental analysis, we identified that bird guano was a significant source for heavy metals Cu, Zn, and Hg. Cu and Zn levels in these guano samples are comparable to their levels in wildbird feces, but guano Hg was lower than previously reported. Trophic positions significantly impacted transfer efficiency of heavy metals by seabirds. Despite of a common source, trace elements, as well as stable isotopes (i.e., guano δ(13)C and collagen δ(15)N), showed island-specific characteristics. Bird subfossils on larger island had relatively greater metal concentrations and revealed higher trophic positions. Partition of element and isotope levels among the islands suggested that transfer efficacy of seabirds on different islands was different, and bird species were probably unevenly distributed among the islets. Island area is possibly a driving factor for distributions of seabird species.

  10. Molecular variation of Spiranthes sinensis (Orchidaceae) in Japan, with special reference to systematic treatment of seasonally differentiated groups and a dwarf form, f. gracilis, from Yakushima Island.

    Science.gov (United States)

    Tsukaya, Hirokazu

    2005-02-01

    Molecular variations of Spiranthes sinensis Ames var. australis (R.Br.) H. Hara et Kitam. ex Kitam. in Japan were examined to evaluate the validity of the seasonally differentiated groups and a dwarf form of the species, which is endemic to Yakushima Island, Japan. Sequence differences in the plastid trnL-F locus clearly distinguished Japanese S. sinensis var. australis from S. sinensis var. sinensis collected from Ryukyu. In contrast, the trnL-F sequence of S. sinensis var. australis from Sabah, Malaysia, clearly differed from that of Japanese S. sinensis var. australis, suggesting genetic heterogeneity of Spiranthes sinensis var. australis in Asia. Moreover, a molecular analysis based on the sequences of nuclear ITS1 regions indicated that there are two major groups of S. sinensis var. australis in Japan, with a geographic distribution boundary on Kyushu Island. However, the trnL-F and ITS1 sequences did not support the genetic differentiation of the seasonally differentiated groups or the dwarf form from the other Japanese individuals. Based on these molecular data, the systematic treatment of physiological and morphological variations in the Japanese population of S. sinensis. var. australis is discussed.

  11. High Temperature (1649 C, 3000F) Surface Ignition Test Apparatus for Fluids.

    Science.gov (United States)

    1983-03-01

    8217 44 v)1 ECOV 0J. 0 0. 4j 4 00 0C .. F,-44 *.’) 4 440 0 ’ 91 " 90 4.44) E-C’� -4 C 44- 0000 Co4 0004 >.. C 0oco 04. 0.oo v waft a 0. 0 .0. 0- 44,- In E 00 l. )amm v 2:G O 193-5906-19 DA 0 1 FILM

  12. Both core and F proteins of hepatitis C virus could enhance cell proliferation in transgenic mice

    Energy Technology Data Exchange (ETDEWEB)

    Hu, Wen-Ta [Graduate Institute of Medical Biotechnology, Tzu Chi University, Hualien, Taiwan (China); Li, Hui-Chun [Department of Biochemistry, Tzu Chi University, Hualien, Taiwan (China); Lee, Shen-Kao; Ma, Hsin-Chieh; Yang, Chee-Hing; Chen, Hung-Ling [Graduate Institute of Medical Biotechnology, Tzu Chi University, Hualien, Taiwan (China); Lo, Shih-Yen, E-mail: losylo@mail.tcu.edu.tw [Graduate Institute of Medical Biotechnology, Tzu Chi University, Hualien, Taiwan (China); Department of Laboratory Medicine, Buddhist Tzu Chi General Hospital, Hualien, Taiwan (China)

    2013-05-24

    Highlights: •HCV core and F proteins could induce hepatocyte proliferation in the transgenic mice. •β-Catenin signaling pathway was activated by core protein in the transgenic mice. •β-Catenin signaling pathway was activated by myc-F protein in the transgenic mice. •Expression of SMA protein was enhanced by core but not myc-F protein. -- Abstract: The role of the protein encoded by the alternative open reading frame (ARF/F/core+1) of the Hepatitis C virus (HCV) genome in viral pathogenesis remains unknown. The different forms of ARF/F/core+1 protein were labile in cultured cells, a myc-tag fused at the N-terminus of the F protein made it more stable. To determine the role of core and F proteins in HCV pathogenesis, transgenic mice with either protein expression under the control of Albumin promoter were generated. Expression of core protein and F protein with myc tag (myc-F) could be detected by Western blotting analysis in the livers of these mice. The ratio of liver to body weight is increased for both core and myc-F transgenic mice compared to that of wild type mice. Indeed, the proliferating cell nuclear antigen protein, a proliferation marker, was up-regulated in the transgenic mice with core or myc-F protein. Further analyses by microarray and Western blotting suggested that β-catenin signaling pathway was activated by either core or myc-F protein in the transgenic mice. These transgenic mice were further treated with either Diethynitrosamine (a tumor initiator) or Phenobarbital (a tumor promoter). Phenobarbital but not Diethynitrosamine treatment could increase the liver/body weight ratio of these mice. However, no tumor formation was observed in these mice. In conclusion, HCV core and myc-F proteins could induce hepatocyte proliferation in the transgenic mice possibly through β-catenin signaling pathway.

  13. National Conference on New Juvenile Justice Standards, Washington, D.C., 1977

    Science.gov (United States)

    Ter Haar, Alice C.

    1978-01-01

    Describes the standards on rights of minors, abuse and neglect, non-criminal behavior, and schools and education which were adopted at the National Conference on New Juvenile Justice Standards, Washington, D.C., 1977. (Author)

  14. Type IV Wind Turbine Model

    DEFF Research Database (Denmark)

    Hansen, Anca Daniela; Margaris, Ioannis D.

    project to be incorporated in the wind power plant level. This document describes the Type 4 wind turbine simulation model, implemented in the EaseWind project. The implemented wind turbine model is one of the initial necessary steps toward integrating new control services in the wind power plant level....... In the project, this wind turbine model will be further incorporated in a wind power plant model together with the implementation in the wind power control level of the new control functionalities (inertial response, synchronising power and power system damping). For this purpose an aggregate wind power plant...... (WPP) will be considered. The aggregate WPP model, which will be based on the upscaling of the individual wind turbine model on the electrical part, will make use of an equivalent wind speed. The implemented model follows the basic structure of the generic standard Type 4 wind turbine model proposed...

  15. Gas turbines

    Energy Technology Data Exchange (ETDEWEB)

    Farahan, E.; Eudaly, J.P.

    1978-10-01

    This evaluation provides performance and cost data for commercially available simple- and regenerative-cycle gas turbines. Intercooled, reheat, and compound cycles are discussed from theoretical basis only, because actual units are not currently available, except on a special-order basis. Performance characteristics investigated include unit efficiency at full-load and off-design conditions, and at rated capacity. Costs are tabulated for both simple- and regenerative-cycle gas turbines. The output capacity of the gas turbines investigated ranges from 80 to 134,000 hp for simple units and from 12,000 to 50,000 hp for regenerative units.

  16. Wind Turbine Generator System Acoustic Noise Test Report for the Gaia Wind 11-kW Wind Turbine

    Energy Technology Data Exchange (ETDEWEB)

    Huskey, A.

    2011-11-01

    This report details the acoustic noise test conducted on the Gaia-Wind 11-kW wind turbine at the National Wind Technology Center. The test turbine is a two- bladed, downwind wind turbine with a rated power of 11 kW. The test turbine was tested in accordance with the International Electrotechnical Commission standard, IEC 61400-11 Ed 2.1 2006-11 Wind Turbine Generator Systems -- Part 11 Acoustic Noise Measurement Techniques.

  17. [Detection of serum anti-F antibody in hepatitis C virus infected patients].

    Science.gov (United States)

    Deng, Xiao-zhao; Jiang, Churn-mei; Xu, Ke; Wang, Zhong-can; Ding, Wei-liang; Yu, Rong-bin; Wang, Jie; Wu, Chao; Zhang, Yun

    2007-11-01

    To assess the prevalence of serum anti-F in patients with hepatitis C virus (HCV) infection and the distribution of anti-F. The recombinant protein (HCV-F/GST) was coated onto micro titer plates as antigen. Sera of 120 patients with hepatitis C virus infection, 15 patients with hepatitis B, 3 patients with hepatitis E and 10 normal sera were tested by indirect ELISA for detecting anti-F. 82 samples out of the 120 (68%) HCV infected patients exhibited a positive anti-F reaction, showing significant difference from the controls with no HCV infection (P F was higher in patients over 50 year olds (OR = 6.675, 95% CI: 2.407-19.071). Patients of midrange, severe phase and hepatic cirrhosis had higher rate than the others (OR = 2.749, 95% CI: 1.470-5.141). Prevalence and distribution of anti-F in Yixing hepatitis C patients was reported and which might be related to the progression of HCV infection.

  18. Variability of the Wind Turbine Power Curve

    Directory of Open Access Journals (Sweden)

    Mahesh M. Bandi

    2016-09-01

    Full Text Available Wind turbine power curves are calibrated by turbine manufacturers under requirements stipulated by the International Electrotechnical Commission to provide a functional mapping between the mean wind speed v ¯ and the mean turbine power output P ¯ . Wind plant operators employ these power curves to estimate or forecast wind power generation under given wind conditions. However, it is general knowledge that wide variability exists in these mean calibration values. We first analyse how the standard deviation in wind speed σ v affects the mean P ¯ and the standard deviation σ P of wind power. We find that the magnitude of wind power fluctuations scales as the square of the mean wind speed. Using data from three planetary locations, we find that the wind speed standard deviation σ v systematically varies with mean wind speed v ¯ , and in some instances, follows a scaling of the form σ v = C × v ¯ α ; C being a constant and α a fractional power. We show that, when applicable, this scaling form provides a minimal parameter description of the power curve in terms of v ¯ alone. Wind data from different locations establishes that (in instances when this scaling exists the exponent α varies with location, owing to the influence of local environmental conditions on wind speed variability. Since manufacturer-calibrated power curves cannot account for variability influenced by local conditions, this variability translates to forecast uncertainty in power generation. We close with a proposal for operators to perform post-installation recalibration of their turbine power curves to account for the influence of local environmental factors on wind speed variability in order to reduce the uncertainty of wind power forecasts. Understanding the relationship between wind’s speed and its variability is likely to lead to lower costs for the integration of wind power into the electric grid.

  19. Electron attachment and detachment, and the electron affinities of C5F5N and C5HF4N

    Science.gov (United States)

    Van Doren, Jane M.; Kerr, Donna M.; Miller, Thomas M.; Viggiano, A. A.

    2005-09-01

    Rate constants have been measured for electron attachment to C5F5N (297-433K) and to 2,3,5,6-C5HF4N (303K) using a flowing-afterglow Langmuir-probe apparatus (at a He gas pressure of 133Pa). In both cases only the parent anion was formed in the attachment process. The attachment rate constants measured at room temperature are 1.8±0.5×10-7 and 7±3×10-10cm-3s-1, respectively. Rate constants were also measured for thermal electron detachment from the parent anions of these molecules. For C5F5N- detachment is negligible at room temperature, but increases to 2530±890s-1 at 433K. For 2,3,5,6-C5HF4N-, the detachment rate at 303K was 520±180s-1. The attachment/detachment equilibrium yielded experimental electron affinities EA(C5F5N )=0.70±0.05eV and EA(2,3,5,6-C5HF4N )=0.40±0.08eV. Electronic structure calculations were carried out for these molecules and related C5HxF5-xN using density-functional theory and the G3(MP2)‖B3LYP compound method. The EAs are found to decrease by 0.25eV, on average, with each F substitution by H. The calculated EAs are in good agreement with the present experimental results.

  20. Ein Molekül-Atom-Datenmodell für Non-Standard-Anwendungen : Anwendungsanalyse, Datenmodellentwurf und Implementierungskonzepte

    OpenAIRE

    Mitschang, Bernhard

    1988-01-01

    Ziel der vorliegenden Arbeit ist die Erarbeitung und Nutzbarmachung von Datenbankkonzepten für sog. Non-Standard-Anwendungen. Darunter versteht man im OB-Bereich Anwendungen aus den Gebieten CAD/CAM, VLSI-Entwurf, Software-Entwicklung, Büroautomatisierung, Expertensysteme etc. Die zentralen Fragestellungen, zu denen es Antworten zu finden gilt, sind: - Welche Anforderungen werden von den Non-Standard-Anwendungen an die Datenhaltung gestellt? - Wie sehen dazu passende Architekturen und D...

  1. Differential reactivity of putative genotype 2 hepatitis C virus F protein between chronic and recovered infections.

    Science.gov (United States)

    Chuang, Wing Chia-Ming; Allain, Jean-Pierre

    2008-08-01

    To date, all studies regarding hepatitis C virus (HCV) F protein have been based on expression in vitro/in vivo of recombinant protein or monoclonal antibodies derived from genotype 1a or 1b sequences, but not from other genotypes. The objective of this study was to prepare a putative genotype 2 recombinant F protein and evaluate its reactivity in plasma from individuals with chronic HCV infection or who had recovered from infection. One genotype 2 strain was selected for F protein (F-2) and core expression in bacterial culture. An ELISA was developed and applied to samples from patients with chronic infection or recovered infection of various genotypes. The anti-F-2 response in 117 samples showed a significantly higher reactivity in chronic than in recovered HCV-infected blood donors (PF and anti-core was more significant in genotypes 1 and 2 than in genotype 3. Anti-F-2 titres were also significantly higher in chronic than in recovered individuals (PF-2 end-point antibody titre. This study thus demonstrated the antigenicity of genotype 2 HCV F protein, although the exact location of the natural frameshift position remains unknown. The difference in anti-F-2 response between chronic and recovered infection, the cross-reactivity irrespective of genotype and the correlation of antibody response with structural and non-structural antigens suggest that the immune response to F protein is an integral part of the natural HCV infection.

  2. Antibody responses to Borrelia burgdorferi outer surface proteins C and F in experimentally infected Beagle dogs.

    Science.gov (United States)

    Callister, Steven M; LaFleur, Rhonda L; Jobe, Dean A; Lovrich, Steven D; Wasmoen, Terri L

    2015-07-01

    Antibody levels to outer surface proteins C and F (OspC and OspF, respectively) in sera collected from laboratory Beagle dogs at 1, 2, and 4 months after challenge with infected black-legged ticks (Ixodes scapularis) were determined. Each dog was confirmed by culture to harbor Borrelia burgdorferi in the skin (n = 10) or the skin and joints (n = 14). Significant levels of immunoglobulin M (Ig)M or IgG anti-OspC antibodies were detected in single serum samples from only 3 (13%) dogs. Similarly, IgM anti-OspF antibodies were detected in only 1 (4%) serum sample collected from a dog with B. burgdorferi in the skin and joints. In contrast, 4 (29%) dogs with skin and joint infections produced IgG anti-OspF antibodies after 2 months, and the response expanded to include 2 (20%) dogs with skin infection and 4 additional dogs with skin and joint infections (overall sensitivity = 62%) after 4 months. The findings failed to support the utility of OspC-based antibody tests for diagnosing canine Lyme disease, but demonstrated that dogs with B. burgdorferi colonizing joint tissue most often produced significant levels of IgG anti-OspF antibodies. Therefore, additional studies to more thoroughly evaluate the clinical utility of OspF-based antibody tests are warranted. © 2015 The Author(s).

  3. 48 CFR 1833.103 - Protests to the agency. (NASA supplements paragraphs (c), (d) and (f).)

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Protests to the agency. (NASA supplements paragraphs (c), (d) and (f).) 1833.103 Section 1833.103 Federal Acquisition..., DISPUTES, AND APPEALS Protests 1833.103 Protests to the agency. (NASA supplements paragraphs (c), (d) and...

  4. Rose Island, American Samoa, 2006 Sea Surface Temperature and Meterological Standard Mooring - CRED CREWS Near Real Time and Historical Data

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Site - Rose Island, American Samoa, -14.5514, -168.16018 ARGOS ID 27267 Time series data from this mooring provide high resolution sea surface temperature, surface...

  5. Pelton turbines

    CERN Document Server

    Zhang, Zhengji

    2016-01-01

    This book concerns the theoretical foundations of hydromechanics of Pelton turbines from the engineering viewpoint. For reference purposes, all relevant flow processes and hydraulic aspects in a Pelton turbine have been analyzed completely and systematically. The analyses especially include the quantification of all possible losses existing in the Pelton turbine and the indication of most available potential for further enhancing the system efficiency. As a guideline the book therefore supports further developments of Pelton turbines with regard to their hydraulic designs and optimizations. It is thus suitable for the development and design engineers as well as those working in the field of turbo machinery. Many laws described in the book can also be directly used to simplify aspects of computational fluid dynamics (CFD) or to develop new computational methods. The well-executed examples help better understand the related flow mechanics.

  6. Telaprevir: Changing the standard of care of chronic hepatitis C

    Directory of Open Access Journals (Sweden)

    A K Rajani

    2013-01-01

    Full Text Available Chronic hepatitis C is a major public health problem and its burden is expected to increase in the near future. Out of six genotypes of hepatitis C virus (HCV identified, genotype 1 is the most prevalent genotype in America and Europe. With peg-interferon alpha and ribavirin dual therapy, sustained virological response (SVR is achieved in less than half of the patients infected with HCV genotype 1. Moreover, this dual therapy also causes many intolerable adverse effects. Telaprevir is an HCV protease inhibitor approved for chronic hepatitis C genotype 1 mono-infection. It is a type of direct acting antiviral drug acting through inhibition of viral non-structural 3/4A protease. It can be safely administered in mild hepatic dysfunction. Due to inhibition of CYP3A4 and P-glycoprotein, significant drug-drug interactions are possible with telaprevir. Trials have shown significantly higher SVR rates when telaprevir is added to peg-interferon alpha and ribavirin, particularly in patients with unfavorable prognostic factors. It is approved for use in treatment-naïve and previously treated patients. Rash and anemia are the major troublesome side-effects. Next-generation protease inhibitors may overcome the drawbacks of telaprevir and another approved HCV protease inhibitor - boceprevir. Evidence from small scale studies suggests that telaprevir may be used in conditions like HIV co-infection, post-transplantation and some HCV non-1 genotype infections also. Preliminary data show higher SVR rates with triple therapy even in patients with unfavorable interleukin-28B (IL28B genotype. With development of other direct acting antivirals, it might be possible to treat chronic hepatitis C with interferon-free regimens in future. This article briefly reviews the properties of telaprevir and its status in the context of rapidly evolving aspects of management of chronic hepatitis C.

  7. First identification of kdr allele F1534S in VGSC gene and its association with resistance to pyrethroid insecticides in Aedes albopictus populations from Haikou City, Hainan Island, China.

    Science.gov (United States)

    Chen, Huiying; Li, Kaili; Wang, Xiaohua; Yang, Xinyan; Lin, Yi; Cai, Fang; Zhong, Wenbin; Lin, Chunyan; Lin, Zhongling; Ma, Yajun

    2016-05-02

    Aedes albopictus is distributed widely in China, as a primary vector of Dengue fever and Chikungunya fever in south of China. Chemical insecticide control is one of the integrated programmes to prevent mosquito-borne diseases. Long-term applications of pyrethroids have resulted in the development of resistance in Ae. albopictus populations in China. However, the susceptibility of Ae. albopictus to pyrethroids in Hainan Island was unclear. Knockdown resistance (kdr), caused by point mutations in the VGSC gene, is one of the mechanisms that confer resistance to DDT and pyrethroids. This study was to investigate the resistance level of Ae. albopictus populations in Haikou City to three pyrethroid insecticides, and elucidate the relationship between the resistant phenotype and kdr mutations. The Aedes albopictus samples were collected in Xinbu Island (XI), Longtang Town (LT), Shishan Town (ST), Baishamen Park (BP), and Flower Market (FM) from Haikou City, Hainan Island, China. The larval susceptibility to deltamethrin, permethrin and beta-cypermethrin was tested by larval bioassays, and adult susceptibility to deltamethrin and DDT was determined by adult bioassays. The degree of resistance was determined by resistance ratio value (RR50 > 3) for larvae and by mortality for adult. The kdr alleles at codon 1534 of the VGSC gene were genotyped. The relationship between kdr genotypes and resistant phenotypes was analyzed by Chi-square test. Out of five populations, assessed by larval bioassays, XI was susceptible to deltamethrin and permethrin; LT was susceptible to permethrin and beta-cypermethrin; and ST was susceptible to permithrin. FM and BP both were resistant to all of the three pyrethroids, and FM showed the highest degree of resistance, with RR50 values from 65.17 to 436.36. A total of 493 individuals from the larval bioassays were genotyped for kdr alleles. Five alleles were detected, including two wildtype alleles, TTC(F) (67.04 %) and TTT(F) (0.41 %), and

  8. Steam turbine materials and corrosion

    Energy Technology Data Exchange (ETDEWEB)

    Holcomb, G.R.; Ziomek-Moroz, M.

    2007-01-01

    Ultra supercritical (USC) power plants offer the promise of higher efficiencies and lower emissions. Current goals of the U.S. Department of Energy’s Advanced Power Systems Initiatives include coal generation at 60% efficiency, which would require steam temperatures of up to 760°C. This research examines the steamside oxidation of alloys for use in USC systems, with emphasis placed on applications in high- and intermediate-pressure turbines. The list of alloys being examined is discussed, including the addition of new alloys to the study. These include alloy 625, selected because of its use as one of the two alloys used for turbine rotors, valves, casings, blading and bolts in the European AD700 full-scale demonstration plant (Scholven Unit F). The other alloy, alloy 617, is already one of the alloys currently being examined by this project. Other new alloys to the study are the three round robin alloys in the UK-US collaboration: alloys 740, TP347HFG, and T92. Progress on the project is presented on cyclic oxidation in 50% air – 50% water vapor, furnace exposures in moist air, and thermogravimetric analysis in argon with oxygen saturated steam. An update on the progress towards obtaining an apparatus for high pressure exposures is given.

  9. Wind turbines

    Energy Technology Data Exchange (ETDEWEB)

    Yeoman, J.C. Jr.

    1978-12-01

    This evaluation of wind turbines is part of a series of Technology Evaluations of possible components and subsystems of community energy systems. Wind turbines, ranging in size from 200 W to 10 MW, are discussed as candidates for prime movers in community systems. Estimates of performance characteristics and cost as a function of rated capacity and rated wind speed are presented. Data concerning material requirements, environmental effects, and operating procedures also are given and are represented empirically to aid computer simulation.

  10. Structure, stability, and thermochemistry of the fullerene derivatives C(64)X(6) (X = H, F, Cl).

    Science.gov (United States)

    Xu, Lei; Shao, Xueguang; Cai, Wensheng

    2009-10-08

    The geometrical structures, electronic properties, and stabilities of the unconventional fullerene derivatives C(64)X(6) (X = H, F, Cl) have been systematically studied by the first-principle calculations based on the density functional theory. The fullerene derivatives 1911(2)-C(64)X(6) generated from the pineapple-shaped C(64)X(4) are predicted to possess the lowest energies. The other two X atoms are added to the carbon atoms with the highest local strain assessed by the pyramidalization angles. The calculations of the nucleus-independent chemical shifts suggest that the aromaticity of C(64)X(6) affects the stability order of the derivative isomers. To address why C(64)H(6) was not observed in the experimental study of Wang et al. (J. Am. Chem. Soc. 2006, 128, 6605) and if the halogenated derivatives C(64)X(6) (X = F, Cl) can be synthesized, thermochemical analysis of the reaction C(64)X(4) + X(2) --> C(64)X(6) was also performed. The results indicate that the formation of C(64)H(6) and C(64)Cl(6) is not favored at high temperatures. The former may be a reason why C(64)H(6) was not found in the experiment. In sharp contrast, the Gibbs free energy change to form C(64)F(6) is found to be -23.29 kcal/mol at 2000 K, suggesting that this compound may be formed and detected in experiments. The NMR and IR spectra of 1911(2)-C(64)F(6) are sequentially calculated and presented to facilitate future experimental identification.

  11. Middle Turbinate Osteoma

    National Research Council Canada - National Science Library

    Daneshi, Ahmad; Jalessi, Maryam; Heshmatzade-Behzadi, Ashkan

    2010-01-01

    Osteoma is the most common benign tumor of the paranasal sinuses. Turbinate osteomas are very rare and only four middle turbinate, one superior turbinate and one inferior turbinate osteoma cases have been reported...

  12. Comparative chemical and molecular variability of Cananga odorata (Lam.) Hook.f. & Thomson forma genuina (ylang-ylang) in the Western Indian Ocean Islands: implication for valorization.

    Science.gov (United States)

    Benini, Céline; Mahy, Grégory; Bizoux, Jean-Philippe; Wathelet, Jean-Paul; du Jardin, Patrick; Brostaux, Yves; Fauconnier, Marie-Laure

    2012-07-01

    Cananga odorata (Lam.) Hook.f. & Thomson forma genuina (Annonaceae) is a tropical tree, grown for the production of ylang-ylang essential oil, which is extracted from its fresh and mature flowers. Despite its economic and social importance, very little information is available on its variability and the possible factors causing it. Therefore, the relationship between the genetic structure, revealed by amplified fragment length polymorphism (AFLP), and the essential oil chemical composition, determined by GC/MS analysis, of ylang-ylang grown in semi-managed systems in three Indian Ocean islands (Grande Comore, Mayotte, and Madagascar) was investigated. Our results revealed a low genetic variation within plantations and contrasted situations between islands. Variations of the chemical composition could be observed within plantations and between islands. The genetic differentiation pattern did not match the observed pattern of chemical variability. Hence, the chemical variation could not be attributed to a genetic control. As Grande Comore, Madagascar, and Mayotte present different environmental and agronomic conditions, it can be concluded that the influence of these conditions on the ylang-ylang essential oil composition is consistent with the patterns observed. Finally, several strategies were proposed to valorize the chemical composition variations. Copyright © 2012 Verlag Helvetica Chimica Acta AG, Zürich.

  13. Advantages of air conditioning and supercharging an LM6000 gas turbine inlet

    Energy Technology Data Exchange (ETDEWEB)

    Kolp, D.A. [Kolp Engineering, Avon, CT (United States); Flye, W.M. [Stewart and Stevenson, Houston, TX (United States); Guidotti, H.A. [Energy Services, Inc., Framington, CT (United States)

    1995-07-01

    Of all the external factors affecting a gas turbine, inlet pressure and temperature have the greatest impact on performance. The effect of inlet temperature variations is especially pronounced in the new generation of high-efficiency gas turbines typified by the 40 MW GE LM6000. A reduction of 50 F (28 C) in inlet temperature can result in a 30 percent increase in power and a 4.5 percent improvement in heat rate. An elevation increase to 5,000 ft (1,524 m) above sea level decreases turbine output 17 percent; conversely supercharging can increase output more than 20 percent. This paper addresses various means of heating, cooling and supercharging LM6000 inlet air. An economic model is developed and sample cases are cited to illustrate the optimization of gas turbine inlet systems, taking into account site conditions, incremental equipment cost and subsequent performance enhancement.

  14. NODC Standard Format Marine Mammals of Coastal Alaska Data (1975-1976): Marine Mammal Sighting 2 (F026) (NODC Accession 0014151)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NODC maintains data in three NODC Standard Format Marine Mammal Data Sets: Marine Mammal Sighting and Census (F127); Marine Mammal Specimens (F025); Marine Mammal...

  15. Electrochemical studies of the molten system K2NbF7-Na2O-Nb-(LiF-NaF-KF)(eut) at 700 degrees C

    DEFF Research Database (Denmark)

    Rosenkilde, C.; Vik, A.; Østvold, T.

    2000-01-01

    Various voltammetric methods have been used to study FLINAK (LiF-NaF-KF eutectic melt 46.5-11.5-42 mol %) melts containing about 1 mol % niobium-fluoro and -oxofluoro complexes with Nh in oxidation states (V) and (IV) at 700 degrees C and varying amounts of Na2O in the range 0 ... indications of the coexistence of the oxygen rich Nb(V)OF complexes and O-2(-) ions in FLINAK at n(O)(0)/n(Nb)(0) > 4 have been found. An equilibrium/sampling/analysis technique was also used to study this system without Nb metal added. The results mainly agree with the results of the voltammetric studies...

  16. Estradiol Receptors Regulate Differential Connexin 43 Expression in F98 and C6 Glioma Cell Lines.

    Directory of Open Access Journals (Sweden)

    Zahra Moinfar

    Full Text Available Glioma is the most common malignant primary brain tumour with male preponderance and poor prognosis. Glioma cells express variable amounts of connexin 43 (Cx43 and estrogen receptors (ERs. Both, Cx43 and ERs, play important roles in cell proliferation and migration. Therefore, we investigated the effects of 17-ß estradiol (E2 on Cx43 expression in two glioma cell lines with variable native expression of Cx43.F98 and C6 rat glioma cells were cultured for 24 h in the presence of 10 nM or 100 nM E2, and the E2-antagonist, Fulvestrant. An MTT assay was performed to evaluate cell viability. ERα, ERβ and Cx43 protein expressions were analysed by western blotting and Cx43 mRNA expression was analysed by real-time polymerase chain reaction. To quantify cell migration, an exclusive zone migration assay was used. Functional coupling of cells via gap junctions was examined using whole-cell patch-clamp technique.E2 reduced Cx43 expression in C6 cells, but increased Cx43 expression in F98 cultures. These effects were mediated via ERs. Moreover, E2 promoted C6 cell migration, but it did not affect F98 cell migration. The expression level of ERα was found to be high in C6, but low in F98 cells. ERβ was exclusively expressed in C6 cells. In addition, E2 treatment induced a significant decrease of ERβ in C6 cultures, while it decreased ERα expression in F98 glioma cells.These findings show that E2 differentially modulates Cx43 expression in F98 and C6 glioma cells, likely due to the differential expression of ERs in each of these cell lines. Our findings point to the molecular mechanisms that might contribute to the gender-specific differences in the malignancy of glioma and could have implications for therapeutic strategies against glioma.

  17. D+ to mu+nu and fD+ from 281 pb-1 at Psi(3770) from CLEO-c

    CERN Document Server

    Gao, Y

    2005-01-01

    We report improved measurements of branching fraction and decay constant fD+ in D+ to mu+nu using 281 pb-1 of data taken on the Psi(3770) resonance with the CLEO-c detector. We extract a relatively precise value for the decay constant of the D+ meson by measuring Br(D+ to mu+nu) = (4.40+-0.66+0.09-0.12)x10^-4 and find fD+ = (222.6+-16.7+2.8-3.4) MeV. We also set 90% confidence upper limit on Br(D+ to e+nu) < 2.4x10^-5 which limits contributions from non-Standard Model physics.

  18. Theoretical study of the decomposition mechanism of environmentally friendly insulating medium C3F7CN in the presence of H2O in a discharge

    Science.gov (United States)

    Zhang, Xiaoxing; Li, Yi; Xiao, Song; Tian, Shuangshuang; Deng, Zaitao; Tang, Ju

    2017-08-01

    C3F7CN has been the focus of the alternative gas research field over the past two years because of its excellent insulation properties and environmental characteristics. Experimental studies on its insulation performance have made many achievements. However, few studies on the formation mechanism of the decomposition components exist. A discussion of the decomposition characteristics of insulating media will provide guidance for scientific experimental research and the work that must be completed before further engineering application. In this study, the decomposition mechanism of C3F7CN in the presence of trace H2O under discharge was calculated based on the density functional theory and transition state theory. The reaction heat, Gibbs free energy, and activation energy of different decomposition pathways were investigated. The ionization parameters and toxicity of C3F7CN and various decomposition products were analyzed from the molecular structure perspective. The formation mechanism of the C3F7CN discharge decomposition components and the influence of trace water were evaluated. This paper confirms that C3F7CN has excellent decomposition characteristics, which provide theoretical support for later experiments and related engineering applications. However, the existence of trace water has a negative impact on C3F7CN’s insulation performance. Thus, strict trace water content standards should be developed to ensure dielectric insulation and the safety of maintenance personnel.

  19. Seroprevalence of Human Immunodeficiency Virus, Hepatitis B Virus, Hepatitis C Virus, and Treponema pallidum Infections among Blood Donors on Bioko Island, Equatorial Guinea.

    Directory of Open Access Journals (Sweden)

    Dong-De Xie

    Full Text Available Regular screening of transfusion-transmissible infections (TTIs, such as human immunodeficiency virus (HIV, hepatitis B and hepatitis C virus (HBV and HCV, respectively, and Treponema pallidum, in blood donors is essential to guaranteeing clinical transfusion safety. This study aimed to determine the seroprevalence of four TTIs among blood donors on Bioko Island, Equatorial Guinea (EG.A retrospective survey of blood donors from January 2011 to April 2013 was conducted to assess the presence of HIV, HBV, HCV and T. pallidum. The medical records were analyzed to verify the seroprevalence of these TTIs among blood donations stratified by gender, age and geographical region.Of the total 2937 consecutive blood donors, 1098 (37.39% had a minimum of one TTI and 185 (6.29% harbored co-infections. The general seroprevalence of HIV, HBV, HCV and T. pallidum were 7.83%, 10.01%, 3.71% and 21.51%, respectively. The most frequent TTI co-infections were HBV-T. pallidum 60 (2.04% and HIV-T. pallidum 46 (1.57%. The seroprevalence of HIV, HBV, HCV and T. pallidum were highest among blood donors 38 to 47 years, 18 to 27 years and ≥ 48 years age, respectively (P<0.05. The seroprevalence of TTIs varied according to the population from which the blood was collected on Bioko Island.Our results firstly provide a comprehensive overview of TTIs among blood donors on Bioko Island. Strict screening of blood donors and improved hematological examinations using standard operating procedures are recommended.

  20. Seroprevalence of Human Immunodeficiency Virus, Hepatitis B Virus, Hepatitis C Virus, and Treponema pallidum Infections among Blood Donors on Bioko Island, Equatorial Guinea.

    Science.gov (United States)

    Xie, Dong-De; Li, Jian; Chen, Jiang-Tao; Eyi, Urbano Monsuy; Matesa, Rocio Apicante; Obono, Maximo Miko Ondo; Ehapo, Carlos Sala; Yang, Li-Ye; Yang, Hui; Yang, Hui-Tian; Lin, Min

    2015-01-01

    Regular screening of transfusion-transmissible infections (TTIs), such as human immunodeficiency virus (HIV), hepatitis B and hepatitis C virus (HBV and HCV, respectively), and Treponema pallidum, in blood donors is essential to guaranteeing clinical transfusion safety. This study aimed to determine the seroprevalence of four TTIs among blood donors on Bioko Island, Equatorial Guinea (EG). A retrospective survey of blood donors from January 2011 to April 2013 was conducted to assess the presence of HIV, HBV, HCV and T. pallidum. The medical records were analyzed to verify the seroprevalence of these TTIs among blood donations stratified by gender, age and geographical region. Of the total 2937 consecutive blood donors, 1098 (37.39%) had a minimum of one TTI and 185 (6.29%) harbored co-infections. The general seroprevalence of HIV, HBV, HCV and T. pallidum were 7.83%, 10.01%, 3.71% and 21.51%, respectively. The most frequent TTI co-infections were HBV-T. pallidum 60 (2.04%) and HIV-T. pallidum 46 (1.57%). The seroprevalence of HIV, HBV, HCV and T. pallidum were highest among blood donors 38 to 47 years, 18 to 27 years and ≥ 48 years age, respectively (P<0.05). The seroprevalence of TTIs varied according to the population from which the blood was collected on Bioko Island. Our results firstly provide a comprehensive overview of TTIs among blood donors on Bioko Island. Strict screening of blood donors and improved hematological examinations using standard operating procedures are recommended.

  1. The DOE Next-Generation Drivetrain for Wind Turbine Applications: Gearbox, Generator, and Advanced Si/SiC Hybrid Inverter System: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Erdman, William; Keller, Jonathan

    2016-08-01

    This paper reports on the design and testing results from the U.S. Department of Energy Next-Generation Wind Turbine Drivetrain Project. The drivetrain design reduces the cost of energy by increasing energy capture through drivetrain efficiency improvements; by reducing operation and maintenance costs through reducing gearbox failures; and by lowering capital costs through weight reduction and a series of mechanical and electronic innovations. The paper provides an overview of the drivetrain gearbox and generator and provides a deeper look into the power converter system. The power converter has a number of innovations including the use of hybrid silicon (Si)/silicon carbide (SiC) isolated baseplate switching modules. Switching energies are compared between SiC and Si PIN diodes. The efficiency improvement by use of the SiC diode in a three-level converter is also described. Finally, a brief discussion covering utility interconnect requirements for turbines is provided with a particular focus on utility events that lead to high transient torque loads on drivetrain mechanical elements.

  2. Origin of the high p-doping in F intercalated graphene on SiC

    KAUST Repository

    Cheng, Yingchun

    2011-08-04

    The atomic and electronic structures of F intercalated epitaxialgraphene on a SiC(0001) substrate are studied by first-principles calculations. A three-step fluorination process is proposed. First, F atoms are intercalated between the graphene and the SiC, which restores the Dirac point in the band structure. Second, saturation of the topmost Si dangling bonds introduces p-doping up to 0.37 eV. Third, F atoms bond covalently to the graphene to enhance the p-doping. Our model explains the highly p-doped state of graphene on SiC after fluorination [A. L. Walter et al., Appl. Phys. Lett. 98, 184102 (2011)].

  3. Deposition of B{sub 4}C/BCN/c-BN multilayered thin films by r.f. magnetron sputtering

    Energy Technology Data Exchange (ETDEWEB)

    Bejarano, G. [Laboratorio de Recubrimientos Duros del CDT-ASTIN SENA, Cali (Colombia); Caicedo, J.M. [Laboratorio de Recubrimientos Duros del CDT-ASTIN SENA, Cali (Colombia); Baca, E. [Departamento de Fisica, Universidad del Valle, A.A. 25360, Cali (Colombia); Prieto, P. [Departamento de Fisica, Universidad del Valle, A.A. 25360, Cali (Colombia)]. E-mail: pprieto@calima.univalle.edu.co; Balogh, A.G. [Institute for Material Science, Darmstadt University of Technology (Germany); Enders, S. [Max Plank Institute, Department of Material Research, Stuttgart (Germany)

    2006-01-03

    Thin films of cubic boron nitride (c-BN) and B{sub 4}C/BCN/c-BN multilayers, were deposited by r.f. (13.56 MHz) multi-target magnetron sputtering from high-purity (99.99%) h-BN and a (99.5%) B{sub 4}C targets, in an Ar (90%)/N{sub 2} (10%) gas mixture. Films were deposited onto silicon substrates with (100) orientations at 300 {sup o}C, with r.f. power density near 7 W/cm{sup 2}. In order to obtain the highest fraction of the c-BN phase, an r.f. substrate bias voltage between - 100 and - 300 V was applied during the initial nucleation process and - 50 to - 100 V during the film growth. Additionally, B{sub 4}C and BCN films were deposited and analyzed individually. For their deposition, we varied the bias voltage of the B{sub 4}C films between - 50 and - 250 V, and for the BCN coatings, the nitrogen gas flow from 3% to 12%. A 300-nm-thick TiN buffer layer was first deposited to improve the adhesion of all samples. X-ray diffraction patterns revealed the presence of c-BN (111) and h-BN phases. FTIR spectroscopy measurements indicate the presence of a peak at 780 cm{sup -} {sup 1} referred to as 'out-of-plane' h-BN vibration mode; another peak at 1100 cm{sup -} {sup 1} corresponds to the c-BN TO mode and the 'in-plane' vibration mode of the h-BN at 1400 cm{sup -} {sup 1}. BN films deposited at 300 deg. C at a pressure of 4.0 Pa and under - 150 V of nucleation r.f. bias, applied for 35 min, presented the highest c-BN fraction, near 85%. By using 32 layers, it was possible to deposit a 4.6-{mu}m-thick c-BN film with adequate mechanical properties and good adhesion to the substrate.

  4. Fluorine detected 2D NMR experiments for the practical determination of size and sign of homonuclear F-F and heteronuclear C-F multiple bond J-coupling constants in multiple fluorinated compounds

    Science.gov (United States)

    Aspers, Ruud L. E. G.; Ampt, Kirsten A. M.; Dvortsak, Peter; Jaeger, Martin; Wijmenga, Sybren S.

    2013-06-01

    The use of fluorine in molecules obtained from chemical synthesis has become increasingly important within the pharmaceutical and agricultural industry. NMR characterization of these compounds is of great value with respect to their structure elucidation, their screening in metabolomics investigations and binding studies. The favorable NMR properties of the fluorine nucleus make NMR with fluorine detection of great value in this respect. A suite of NMR 2D F-F- and F-C-correlation experiments with fluorine detection was applied to the assignment of resonances, nJCF- and nJFF-couplings as well as the determination of their size and sign. The utilization of this experiment suite was exemplarily demonstrated for a highly fluorinated vinyl alkyl ether. Especially F-C HSQC and J-scaled F-C HMBC experiments allowed determining the size of the J-couplings of this compound. The relative sign of its homo- and heteronuclear couplings was achieved by different combinations of 2D NMR experiments, including non-selective and F2-selective F-C XLOC, F2-selective F-C HMQC, and F-F COSY. The F2-one/two-site selective F-C XLOC versions were found highly useful, as they led to simplifications of the common E.COSY patterns and resulted in a higher confidence level of the assignment by using selective excitation. The combination of F2-one/two-site selective F-C XLOC experiments with a F2-one-site selective F-C HMQC experiment provided the signs of all nJCF- and nJFF-couplings in the vinyl moiety of the test compound. Other combinations of experiments were found useful as well for special purposes when focusing for example on homonuclear couplings a combination of F-F COSY-10 with a F2-one-site selective F-C HMQC could be used. The E.COSY patterns in the spectra demonstrated were analyzed by use of the spin-selective displacement vectors, and in case of the XLOC also by use of the DQ- and ZQ-displacement vectors. The variety of experiments presented shall contribute to facilitate the

  5. Using Florida Keys Reference Sites As a Standard for Restoration of Forest Structure in Everglades Tree Islands

    Directory of Open Access Journals (Sweden)

    Michael S. Ross

    2010-01-01

    Full Text Available In south Florida, tropical hardwood forests (hammocks occur in Everglades tree islands and as more extensive forests in coastal settings in the nearby Florida Keys. Keys hammocks have been less disturbed by humans, and many qualify as “old-growth,” while Everglades hammocks have received much heavier use. With improvement of tree island condition an important element in Everglades restoration efforts, we examined stand structure in 23 Keys hammocks and 69 Everglades tree islands. Based on Stand Density Index and tree diameter distributions, many Everglades hammocks were characterized by low stocking and under-representation in the smaller size classes. In contrast, most Keys forests had the dense canopies and open understories usually associated with old-growth hardwood hammocks. Subject to the same caveats that apply to off-site references elsewhere, structural information from mature Keys hammocks can be helpful in planning and implementing forest restoration in Everglades tree islands. In many of these islands, such restoration might involve supplementing tree stocking by planting native trees to produce more complete site utilization and a more open understory.

  6. Proyecto de expansión del Villarreal C.F. en México

    OpenAIRE

    Muñoz Muñoz, Rubén

    2014-01-01

    Treball Final de Màster Universitari en Màrqueting i Investigació de Mercats. Codi: SRB100. Curs: 2013/2014 El objetivo fundamental de la elaboración del presente plan de marketing ha sido la realización de un proyecto de expansión del Villarreal C.F. en México. En primer lugar, se ha llevado a cabo un análisis interno del Villarreal C.F. para conocer las fortalezas y debilidades del club. Seguidamente se ha realizado un exhaustivo análisis del macro-entorno, realizando un estu...

  7. Both core and F proteins of hepatitis C virus could enhance cell proliferation in transgenic mice.

    Science.gov (United States)

    Hu, Wen-Ta; Li, Hui-Chun; Lee, Shen-Kao; Ma, Hsin-Chieh; Yang, Chee-Hing; Chen, Hung-Ling; Lo, Shih-Yen

    2013-05-24

    The role of the protein encoded by the alternative open reading frame (ARF/F/core+1) of the Hepatitis C virus (HCV) genome in viral pathogenesis remains unknown. The different forms of ARF/F/core+1 protein were labile in cultured cells, a myc-tag fused at the N-terminus of the F protein made it more stable. To determine the role of core and F proteins in HCV pathogenesis, transgenic mice with either protein expression under the control of Albumin promoter were generated. Expression of core protein and F protein with myc tag (myc-F) could be detected by Western blotting analysis in the livers of these mice. The ratio of liver to body weight is increased for both core and myc-F transgenic mice compared to that of wild type mice. Indeed, the proliferating cell nuclear antigen protein, a proliferation marker, was up-regulated in the transgenic mice with core or myc-F protein. Further analyses by microarray and Western blotting suggested that β-catenin signaling pathway was activated by either core or myc-F protein in the transgenic mice. These transgenic mice were further treated with either Diethynitrosamine (a tumor initiator) or Phenobarbital (a tumor promoter). Phenobarbital but not Diethynitrosamine treatment could increase the liver/body weight ratio of these mice. However, no tumor formation was observed in these mice. In conclusion, HCV core and myc-F proteins could induce hepatocyte proliferation in the transgenic mice possibly through β-catenin signaling pathway. Copyright © 2013 Elsevier Inc. All rights reserved.

  8. Multimodal interaction with W3C standards toward natural user interfaces to everything

    CERN Document Server

    2017-01-01

    This book presents new standards for multimodal interaction published by the W3C and other standards bodies in straightforward and accessible language, while also illustrating the standards in operation through case studies and chapters on innovative implementations. The book illustrates how, as smart technology becomes ubiquitous, and appears in more and more different shapes and sizes, vendor-specific approaches to multimodal interaction become impractical, motivating the need for standards. This book covers standards for voice, emotion, natural language understanding, dialog, and multimodal architectures. The book describes the standards in a practical manner, making them accessible to developers, students, and researchers. Comprehensive resource that explains the W3C standards for multimodal interaction clear and straightforward way; Includes case studies of the use of the standards on a wide variety of devices, including mobile devices, tablets, wearables and robots, in applications such as assisted livi...

  9. CLEC4F is an inducible C-type lectin in F4/80-positive cells and is involved in alpha-galactosylceramide presentation in liver.

    Directory of Open Access Journals (Sweden)

    Chih-Ya Yang

    Full Text Available CLEC4F, a member of C-type lectin, was first purified from rat liver extract with high binding affinity to fucose, galactose (Gal, N-acetylgalactosamine (GalNAc, and un-sialylated glucosphingolipids with GalNAc or Gal terminus. However, the biological functions of CLEC4F have not been elucidated. To address this question, we examined the expression and distribution of murine CLEC4F, determined its binding specificity by glycan array, and investigated its function using CLEC4F knockout (Clec4f-/- mice. We found that CLEC4F is a heavily glycosylated membrane protein co-expressed with F4/80 on Kupffer cells. In contrast to F4/80, CLEC4F is detectable in fetal livers at embryonic day 11.5 (E11.5 but not in yolk sac, suggesting the expression of CLEC4F is induced as cells migrate from yolk cells to the liver. Even though CLEC4F is not detectable in tissues outside liver, both residential Kupffer cells and infiltrating mononuclear cells surrounding liver abscesses are CLEC4F-positive upon Listeria monocytogenes (L. monocytogenes infection. While CLEC4F has strong binding to Gal and GalNAc, terminal fucosylation inhibits CLEC4F recognition to several glycans such as Fucosyl GM1, Globo H, Bb3∼4 and other fucosyl-glycans. Moreover, CLEC4F interacts with alpha-galactosylceramide (α-GalCer in a calcium-dependent manner and participates in the presentation of α-GalCer to natural killer T (NKT cells. This suggests that CLEC4F is a C-type lectin with diverse binding specificity expressed on residential Kupffer cells and infiltrating monocytes in the liver, and may play an important role to modulate glycolipids presentation on Kupffer cells.

  10. SCALE: A modular code system for performing standardized computer analyses for licensing evaluation: Functional modules, F9-F11

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-03-01

    This Manual represents Revision 5 of the user documentation for the modular code system referred to as SCALE. The history of the SCALE code system dates back to 1969 when the current Computational Physics and Engineering Division at Oak Ridge National Laboratory (ORNL) began providing the transportation package certification staff at the U.S. Atomic Energy Commission with computational support in the use of the new KENO code for performing criticality safety assessments with the statistical Monte Carlo method. From 1969 to 1976 the certification staff relied on the ORNL staff to assist them in the correct use of codes and data for criticality, shielding, and heat transfer analyses of transportation packages. However, the certification staff learned that, with only occasional use of the codes, it was difficult to become proficient in performing the calculations often needed for an independent safety review. Thus, shortly after the move of the certification staff to the U.S. Nuclear Regulatory Commission (NRC), the NRC staff proposed the development of an easy-to-use analysis system that provided the technical capabilities of the individual modules with which they were familiar. With this proposal, the concept of the Standardized Computer Analyses for Licensing Evaluation (SCALE) code system was born. This volume consists of the section of the manual dealing with three of the functional modules in the code. Those are the Morse-SGC for the SCALE system, Heating 7.2, and KENO V.a. The manual describes the latest released versions of the codes.

  11. CYP4F18-Deficient Neutrophils Exhibit Increased Chemotaxis to Complement Component C5a

    Directory of Open Access Journals (Sweden)

    Rachel Vaivoda

    2015-01-01

    Full Text Available CYP4Fs were first identified as enzymes that catalyze hydroxylation of leukotriene B4 (LTB4. CYP4F18 has an unusual expression in neutrophils and was predicted to play a role in regulating LTB4-dependent inflammation. We compared chemotaxis of wild-type and Cyp4f18 knockout neutrophils using an in vitro assay. There was no significant difference in the chemotactic response to LTB4, but the response to complement component C5a increased 1.9–2.25-fold in knockout cells compared to wild-type (P < 0.01. This increase was still observed when neutrophils were treated with inhibitors of eicosanoid synthesis. There were no changes in expression of other CYP4 enzymes in knockout neutrophils that might compensate for loss of CYP4F18 or lead to differences in activity. A mouse model of dextran sodium sulfate colitis was used to investigate the consequences of increased C5a-dependent chemotaxis in vivo, but there was no significant difference in weight loss, disease activity, or colonic tissue myeloperoxidase between wild-type and Cyp4f18 knockout mice. This study demonstrates the limitations of inferring CYP4F function based on an ability to use LTB4 as a substrate, points to expanding roles for CYP4F enzymes in immune regulation, and underscores the in vivo challenges of CYP knockout studies.

  12. 4- {sup 18}F]fluoroarylalkylethers via an improved synthesis of n.c.a. 4- {sup 18}F]fluorophenol

    Energy Technology Data Exchange (ETDEWEB)

    Ludwig, Thomas; Ermert, Johannes E-mail: j.ermert@fz-juelich.de; Coenen, Heinz H

    2002-02-01

    This paper describes the improved synthesis of n.c.a. 4- {sup 18}F]fluorophenol for the preparation of {sup 18}F-labeled alkylarylethers. Nucleophilic fluorination of substituted benzophenone derivatives yielded n.c.a. 4- {sup 18}F]fluoro-4'-substituted benzophenones with 80- 90 % RCY, which were converted to benzoic acid phenylesters by treatment with peracetic acid. Strong electron-withdrawing substituents like nitro, cyano and trifluoromethyl favor a fluorophenyl-to-oxygen migration resulting in the formation of corresponding benzoic acid fluorophenylesters. N.c.a. {sup 18}F]fluorophenol is almost quantitatively formed after hydrolysis and can easily be converted with alkylhalides into n.c.a. {sup 18}F]fluoroarylalkylethers.

  13. A Control Method for Balancing the SoC of Distributed Batteries in Islanded Converter-Interfaced Microgrids

    Directory of Open Access Journals (Sweden)

    Spyros I. Gkavanoudis

    2016-01-01

    Full Text Available In a low-voltage islanded microgrid powered by renewable energy sources, the energy storage systems (ESSs are considered necessary, in order to maintain the power balance. Since a microgrid can be composed of several distributed ESSs (DESSs, a coordinated control of their state-of-charge (SoC should be implemented, ensuring the prolonged lifespan. This paper proposes a new decentralized control method for balancing the SoC of DESSs in islanded microgrids, without physical communication. Each DESS injects a current distortion at 175 Hz, when its SoC changes by 10%. This distortion is recognized by every DESS, through a phase-locked loop (PLL. In order to distinguish the origin of the distortion, each DESS injects a distortion of different time duration. This intermediate frequency has been selected in order to avoid the concurrence with the usual harmonics. The DESSs take advantage of this information and inject a current proportional to the SoC. Implementing this strategy, a comparable number of charging/discharging cycles for each DESS are achieved. Furthermore, an active filter operation, implemented in the dq rotating frame for each individual harmonic, is integrated in the control of the distributed generation units, supplying nonlinear loads with high-quality voltage. The effectiveness of this method is verified by detailed simulation results.

  14. Aziridines in the synthesis of {sup 11}C- and {sup 18}F-labelled compounds

    Energy Technology Data Exchange (ETDEWEB)

    Gillings, N.M

    1998-07-01

    Racemic [4-{sup 11}C]aspartic acid, [4-{sup 11}C]asparagine and 2,4-diamino[4-{sup 11}C]butyric acid were synthesised by the ring-opening of an N-activated aziridine-2-carboxylate with [{sup 11}C]cyanide, followed by preparative HPLC and hydrolysis/reduction. These labelled amino acids arise from nucleophilic attack at the {beta}-carbon of the aziridine ring. A radioactive by-product of ca. 25% was attributed to the product of {alpha}-attack. Several N-activated 2-aryl aziridines were synthesised for the attempted synthesis of {beta}-[{sup 18}F] fluorophenylalanine and {beta}-[{sup 18}F]fluorodopa. Ring-opening with [{sup 18}F]fluoride showed no evidence of {beta}-fluorinated products and it is proposed that attack occurs exclusively at the {alpha}-carbon, giving the corresponding {alpha}-[{sup 18}F]fluoro-{beta}-amino acids. Further evidence for this was the reaction of the {beta}-unsubstituted N-activated aziridine-2-carboxylate with [{sup 18}F]fluoride. This reaction was totally regiospecific and afforded exclusively the {alpha}-substituted product, {alpha}-[{sup 18}F]fluoro-{beta}-alanine. Aziridine precursors were resolved by chiral HPLC. On labelling the chiral aziridines, however, racemic {sup 11}C- and {sup 18}F-labelled amino acids were obtained. This was attributed to racemisation of the initially formed ring-opened products. The use of [{sup 11}C]methyl lithium as a nucleophile for aziridine ring-opening was investigated. Reaction was expected to occur at low temperature, thus potentially avoiding racemisation. No products corresponding to aziridine ring-opening with [{sup 11}C]methyl lithium were, however, observed. A difluorinated analogue of amphetamine was synthesised by fluorination of an azirine (via an aziridine). This racemic compound was resolved as its chiral tartarate salts and subsequently labelled by methylation with [{sup 11}C]methyl iodide, giving the novel compound {beta}, {beta}-difluoro[N-methyl-{sup 11}C]methamphetamine in high

  15. Influences of micro-geomorphology on the stoichiometry of C, N and P in Chenier Island soils and plants in the Yellow River Delta, China.

    Science.gov (United States)

    Qu, Fanzhu; Meng, Ling; Yu, Junbao; Liu, Jingtao; Sun, Jingkuan; Yang, Hongjun; Dong, Linshui

    2017-01-01

    Studies have indicated that consistent or well-constrained (relatively low variability) carbon:nitrogen:phosphorus (C:N:P) ratios exist in large-scale ecosystems, including both marine and terrestrial ecosystems. Little is known about the C, N and P stoichiometric ratios that exist in the soils and plants of Chenier Island in the Yellow River Delta (YRD). We examined the distribution patterns and relationships of C, N and P stoichiometry in the soils and plants of Chenier Island, as well as the potential influences of the island's micro-geomorphology. Based on a study of four soil profile categories and Phragmites australis and Suaeda heteroptera plant tissues, our results showed that micro-geomorphology could leave a distinct imprint on the soil and plant elemental stoichiometry of Chenier Island; significant variation in the atomic C:N:P ratios (RCNP) existed in soils and plants, indicating that the RCNP values in both the soil and plants are not well constrained at the Chenier Island scale. RCN and RCP in Chenier Island soils were high, whereas the RNP values were comparatively low, indicating that the ecosystems of Chenier Island are nutrient-limited by N and P. However, the RNP values in P. australis and S. heteroptera plant tissues were high, suggesting that the plants of Chenier Island are nutrient-limited by P. Finally, we suggest that soil and plant N:P ratios may be good indicators of the soil and plant nutrient status during soil development and plant growth, which could be a useful reference for restoring the degraded soils of Chenier Island.

  16. Bacillus subtilis SepF binds to the C-terminus of FtsZ.

    Directory of Open Access Journals (Sweden)

    Ewa Król

    Full Text Available Bacterial cell division is mediated by a multi-protein machine known as the "divisome", which assembles at the site of cell division. Formation of the divisome starts with the polymerization of the tubulin-like protein FtsZ into a ring, the Z-ring. Z-ring formation is under tight control to ensure bacteria divide at the right time and place. Several proteins bind to the Z-ring to mediate its membrane association and persistence throughout the division process. A conserved stretch of amino acids at the C-terminus of FtsZ appears to be involved in many interactions with other proteins. Here, we describe a novel pull-down assay to look for binding partners of the FtsZ C-terminus, using a HaloTag affinity tag fused to the C-terminal 69 amino acids of B. subtilis FtsZ. Using lysates of Escherichia coli overexpressing several B. subtilis cell division proteins as prey we show that the FtsZ C-terminus specifically pulls down SepF, but not EzrA or MinC, and that the interaction depends on a conserved 16 amino acid stretch at the extreme C-terminus. In a reverse pull-down SepF binds to full-length FtsZ but not to a FtsZΔC16 truncate or FtsZ with a mutation of a conserved proline in the C-terminus. We show that the FtsZ C-terminus is required for the formation of tubules from FtsZ polymers by SepF rings. An alanine-scan of the conserved 16 amino acid stretch shows that many mutations affect SepF binding. Combined with the observation that SepF also interacts with the C-terminus of E. coli FtsZ, which is not an in vivo binding partner, we propose that the secondary and tertiary structure of the FtsZ C-terminus, rather than specific amino acids, are recognized by SepF.

  17. SCALE: A modular code system for performing standardized computer analyses for licensing evaluation: Functional modules F1-F8

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-03-01

    This Manual represents Revision 5 of the user documentation for the modular code system referred to as SCALE. The history of the SCALE code system dates back to 1969 when the current Computational Physics and Engineering Division at Oak Ridge National Laboratory (ORNL) began providing the transportation package certification staff at the U.S. Atomic Energy Commission with computational support in the use of the new KENO code for performing criticality safety assessments with the statistical Monte Carlo method. From 1969 to 1976 the certification staff relied on the ORNL staff to assist them in the correct use of codes and data for criticality, shielding, and heat transfer analyses of transportation packages. However, the certification staff learned that, with only occasional use of the codes, it was difficult to become proficient in performing the calculations often needed for an independent safety review. Thus, shortly after the move of the certification staff to the U.S. Nuclear Regulatory Commission (NRC), the NRC staff proposed the development of an easy-to-use analysis system that provided the technical capabilities of the individual modules with which they were familiar. With this proposal, the concept of the Standardized Computer Analyses for Licensing Evaluation (SCALE) code system was born. This volume consists of the section of the manual dealing with eight of the functional modules in the code. Those are: BONAMI - resonance self-shielding by the Bondarenko method; NITAWL-II - SCALE system module for performing resonance shielding and working library production; XSDRNPM - a one-dimensional discrete-ordinates code for transport analysis; XSDOSE - a module for calculating fluxes and dose rates at points outside a shield; KENO IV/S - an improved monte carlo criticality program; COUPLE; ORIGEN-S - SCALE system module to calculate fuel depletion, actinide transmutation, fission product buildup and decay, and associated radiation source terms; ICE.

  18. NODC Standard Format Fish Pathology Format (F013) Data (1975-1980) (NODC Accession 0014146)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Fish Pathology (F013) data set contains data from examinations of diseased fishes. Although these data may be from field observations, they derive primarily from...

  19. NODC Standard Format Marine Bacteria (F009) Data (1975-1979) (NODC Accession 0014148)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Marine Bacteria (F009) data set contains data from bacteriological studies of the water column and ocean bottom. Data include the density (number per unit...

  20. Wind Turbine Generator System Power Performance Test Report for the ARE442 Wind Turbine

    Energy Technology Data Exchange (ETDEWEB)

    van Dam, J.; Jager, D.

    2010-02-01

    This report summarizes the results of a power performance test that NREL conducted on the ARE 442 wind turbine. This test was conducted in accordance with the International Electrotechnical Commission's (IEC) standard, Wind Turbine Generator Systems Part 12: Power Performance Measurements of Electricity Producing Wind Turbines, IEC 61400-12-1 Ed.1.0, 2005-12. However, because the ARE 442 is a small turbine as defined by IEC, NREL also followed Annex H that applies to small wind turbines. In these summary results, wind speed is normalized to sea-level air density.

  1. Phytochemical analysis of the ethanolic extract of Agathis robusta (C. Moore ex F. Muell.) F.M. Bailey.

    Science.gov (United States)

    Venditti, Alessandro; Frezza, Claudio; Campanelli, Chiara; Foddai, Sebastiano; Bianco, Armandodoriano; Serafini, Mauro

    2017-07-01

    This work reports the phytochemical analysis of the ethanolic extract obtained from the leaves of Agathis robusta (C. Moore ex F. Muell.) F.M. Bailey. The methodology utilised during this study comprised classical chromatographic and spectroscopic techniques. Six compounds were identified: agathisflavone (1), 7″-O-methyl-agathisflavone (2), cupressuflavone (3), rutin (4), shikimic acid (5) and (2S)-1,2-Di-O-[(9Z,12Z,15Z)-octadeca-9,12,15-trienoyl]-3-O-β-d-galactopyranosyl glycerol (6). These belong to four major classes of natural compounds: bi-flavonoids (1-3); diglycosidic flavonoids (4); cycloexen-carboxylic acids (5); glycerol-glycolipids (6). To the best of our knowledge, compounds (3-6) were identified for the first time in this study as constituents of A. robusta. Anyway, the majority of these compounds has chemotaxonomic relevance and is mostly in accordance with the current botanical classification of this species. Moreover, they also present several pharmacological properties among which, the antibacterial, anti-inflammatory and protective ones are the most important and may explain why this species is used in the ethno-medicinal field.

  2. Evaluation of a candidate International Standard for Meningococcal Group C polysaccharide.

    Science.gov (United States)

    Vipond, Caroline; Mulloy, Barbara; Rigsby, Peter; Burkin, Karena; Bolgiano, Barbara

    2012-09-01

    Meningococcal group C (MenC) plain polysaccharide (PS) and conjugate vaccines are primarily evaluated by physicochemical methods to ensure that batches are consistently manufactured. As different assays are employed to quantify the MenC PS content of final formulations and bulk intermediaries, there is a need for an International MenC PS Standard to calibrate internal references used in the different laboratories. Twelve laboratories from nine different countries participated in a collaborative study to determine the MenC PS content of a candidate International Standard MenC PS preparation (08/214) and to assess its suitability. On the basis of the results from this study the candidate standard 08/214 was established as an International Standard for the quantification of MenC PS content in vaccines and components. It has a content of 1.192 ± 0.192 mg MenC PS/ampoule (expanded uncertainty with coverage factor of k = 2.365 corresponding to a 95% level of confidence), as determined by the resorcinol assays carried out by eight of the participating laboratories. The standard is available from The National Institute of Biological Standards and Control who act as guardians and distributors of the material under the auspices of WHO. Copyright © 2012 The International Alliance for Biological Standardization. Published by Elsevier Ltd. All rights reserved.

  3. Clinical Application of Standardized Cognitive Assessment Using fMRI. I. Matrix Reasoning

    Directory of Open Access Journals (Sweden)

    Mark D. Allen

    2008-01-01

    Full Text Available Functional MRI is increasingly recognized for its potential as a powerful new tool in clinical neuropsychology. This is likely due to the fact that, with some degree of innovation, it is possible to convert practically any familiar cognitive test into one that can be performed in the MRI scanning environment. However, like any assessment approach, meaningful interpretation of fMRI data for the purpose of patient evaluation crucially requires normative data derived from a sample of unimpaired persons, against which individual patients may be compared. Currently, no such normative data are available for any fMRI-based cognitive testing protocol. In this paper, we report the first of a series of fMRI-compatible cognitive assessment protocols, a matrix reasoning test (f-MRT, for which normative samples of functional activation have been collected from unimpaired control subjects and structured in a manner that makes individual patient evaluation possible in terms of familiar z-score distributions. Practical application of the f-MRT is demonstrated via a contrastive case-study of two individuals with cognitive impairment in which fMRI data identifies subtleties in patient deficits otherwise missed by conventional measures of performance.

  4. Powdery mildew fungal effector candidates share N-terminal Y/F/WxC-motif

    Directory of Open Access Journals (Sweden)

    Emmersen Jeppe

    2010-05-01

    Full Text Available Abstract Background Powdery mildew and rust fungi are widespread, serious pathogens that depend on developing haustoria in the living plant cells. Haustoria are separated from the host cytoplasm by a plant cell-derived extrahaustorial membrane. They secrete effector proteins, some of which are subsequently transferred across this membrane to the plant cell to suppress defense. Results In a cDNA library from barley epidermis containing powdery mildew haustoria, two-thirds of the sequenced ESTs were fungal and represented ~3,000 genes. Many of the most highly expressed genes encoded small proteins with N-terminal signal peptides. While these proteins are novel and poorly related, they do share a three-amino acid motif, which we named "Y/F/WxC", in the N-terminal of the mature proteins. The first amino acid of this motif is aromatic: tyrosine, phenylalanine or tryptophan, and the last is always cysteine. In total, we identified 107 such proteins, for which the ESTs represent 19% of the fungal clones in our library, suggesting fundamental roles in haustoria function. While overall sequence similarity between the powdery mildew Y/F/WxC-proteins is low, they do have a highly similar exon-intron structure, suggesting they have a common origin. Interestingly, searches of public fungal genome and EST databases revealed that haustoria-producing rust fungi also encode large numbers of novel, short proteins with signal peptides and the Y/F/WxC-motif. No significant numbers of such proteins were identified from genome and EST sequences from either fungi which do not produce haustoria or from haustoria-producing Oomycetes. Conclusion In total, we identified 107, 178 and 57 such Y/F/WxC-proteins from the barley powdery mildew, the wheat stem rust and the wheat leaf rust fungi, respectively. All together, our findings suggest the Y/F/WxC-proteins to be a new class of effectors from haustoria-producing pathogenic fungi.

  5. Wind turbine

    Science.gov (United States)

    Cheney, Jr., Marvin C.

    1982-01-01

    A wind turbine of the type having an airfoil blade (15) mounted on a flexible beam (20) and a pitch governor (55) which selectively, torsionally twists the flexible beam in response to wind turbine speed thereby setting blade pitch, is provided with a limiter (85) which restricts unwanted pitch change at operating speeds due to torsional creep of the flexible beam. The limiter allows twisting of the beam by the governor under excessive wind velocity conditions to orient the blades in stall pitch positions, thereby preventing overspeed operation of the turbine. In the preferred embodiment, the pitch governor comprises a pendulum (65,70) which responds to changing rotor speed by pivotal movement, the limiter comprising a resilient member (90) which engages an end of the pendulum to restrict further movement thereof, and in turn restrict beam creep and unwanted blade pitch misadjustment.

  6. Final Technical Report for grant entitled "New Horizons in C-F Activation by Main Group Electrophiles"

    Energy Technology Data Exchange (ETDEWEB)

    Ozerov, Oleg V [Texas A& M University; Ozerov, Oleg V.

    2014-01-16

    We became interested in developing new methods for hydrodefluorination (HDF) and other types of C-F bond conversion in polyfluoroalkanes under mild conditions. We were attracted to an approach to C-F activation, where the key C-F cleavage proceeds by a Lewis acid abstraction of fluoride rather than a redox event. The efforts during the previous period were aimed at a) advancing the HDF reactivity with improvement in scope and catalyst longevity; b) extending C-F activation beyond HDF; c) generating insight about the elementary steps of the reaction and potential intermediates.

  7. C5 Extract Induces Apoptosis in B16F10 Murine Melanoma Cells ...

    African Journals Online (AJOL)

    Methods: The anti-proliferative effects of C5E were assessed by culturing B16F10 cells in the ... phase arrest by interfering with cell regulatory factors such as cyclins B1, D1, D3, and E, and cyclin- ... uncontrolled growth are characteristics of cancer. ..... keratinocyte cells, HaCaT; (b) NCI-H1299, p53 knockout cells; (c) mouse ...

  8. Book Review: C.F. Gronum, "Ou Marico" | Kruger | South African ...

    African Journals Online (AJOL)

    C.F. GRONUM Ou Marico Protea Boekhuis, Pretoria 2009. Slapband, 254 pp. ISBN 978-1-86919-299-0. R175. Full Text: EMAIL FULL TEXT EMAIL FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Article Metrics. Metrics Loading ... Metrics powered by PLOS ALM

  9. Guido Kangur toob C. F. Hahni pubisse jatsu / Urmas Hännile

    Index Scriptorium Estoniae

    Hännile, Urmas

    2009-01-01

    Eesti Draamateatri näitleja ja muusikafestivali Sõru Jazz korraldaja Guido Kanguri eestvõttel hakkab Pärnus C. F. Hahni pubis (Riia mnt 129a) kolmapäeviti kõlama džässmuusika, G. Kanguri tegemistest

  10. C.F Louis Leipoldt (28 Des 1880-12 Apr 1947) | Otto | Scientia ...

    African Journals Online (AJOL)

    Scientia Militaria: South African Journal of Military Studies. Journal Home · ABOUT · Advanced Search · Current Issue · Archives · Journal Home > Vol 9, No 4 (1979) >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register. C.F Louis Leipoldt (28 Des 1880-12 Apr 1947).

  11. Proximate and mineral composition of shea ( vitellaria Paradoxa c.f. ...

    African Journals Online (AJOL)

    The shea tree (Vitellaria paradoxa,C.F.Gaertn) is an indigenous fruit tree distributed in the shea parklands of Africa. The shea fruit is an important source of food for rural communities especially at time of food shortages, hunger and other disasters in addition to providing enormous health benefit and income. Because of its ...

  12. Flood Hazard Recurrence Frequencies for C-, F-, E-, S-, H-, Y-, and Z-Areas

    Energy Technology Data Exchange (ETDEWEB)

    Chen, K.F.

    1999-11-18

    A method was developed to determine the probabilistic flood elevation curves for Savannah River Site facilities. This report presents the method used to determine the probabilistic flood elevation curves for C-, F-, E-, H-, S-, Y-, and Z-Areas due to runoff from the Upper Three Runs and Fourmile Branch basins.

  13. Electron swarm parameter measurements of perfluorobut-2-ene (2-C4F8)

    OpenAIRE

    Chachereau, Alise; Franck, Christian M.

    2015-01-01

    In this contribution, the electron swarm parameters of perfluorobut-2-ene (2-C4F8) mixtures with the buffer gases N2, CO2 and Argon are experimentally investigated. The effective ionization rate constant and electron drift velocity are measured in the entire E/N range up to the critical density-reduced electric field.

  14. Development of standardized air-blown coal gasifier/gas turbine concepts for future electric power systems. Volume 5, Appendix D: Cost support information: Final report

    Energy Technology Data Exchange (ETDEWEB)

    Sadowski, R.S.; Brown, M.J.; Harriz, J.T.; Ostrowski, E.

    1991-01-01

    The cost estimate provided for the DOE sponsored study of Air Blown Coal Gasification was developed from vendor quotes obtained directly for the equipment needed in the 50 MW, 100 MW, and 200 MW sized plants and from quotes from other jobs that have been referenced to apply to the particular cycle. Quotes were generally obtained for the 100 MW cycle and a scale up/down factor was used to generate the cost estimates for the 200 MW and 50 MW cycles, respectively. Information from GTPro (property of Thermoflow, Inc.) was used to estimate the cost of the 200 MW and 50 MW gas turbine, HRSG, and steam turbines. To available the use of GTPro`s estimated values for this equipment, a comparison was made between the quotes obtained for the 100 MW cycle (ABB GT 11N combustion turbine and a HSRG) against the estimated values by GTPro.

  15. The Salmonella genomic island 1 is specifically mobilized in trans by the IncA/C multidrug resistance plasmid family.

    Directory of Open Access Journals (Sweden)

    Gregory Douard

    Full Text Available BACKGROUND: The Salmonella genomic island 1 (SGI1 is a Salmonella enterica-derived integrative mobilizable element (IME containing various complex multiple resistance integrons identified in several S. enterica serovars and in Proteus mirabilis. Previous studies have shown that SGI1 transfers horizontally by in trans mobilization in the presence of the IncA/C conjugative helper plasmid pR55. METHODOLOGY/PRINCIPAL FINDINGS: Here, we report the ability of different prevalent multidrug resistance (MDR plasmids including extended-spectrum β-lactamase (ESBL gene-carrying plasmids to mobilize the multidrug resistance genomic island SGI1. Through conjugation experiments, none of the 24 conjugative plasmids tested of the IncFI, FII, HI2, I1, L/M, N, P incompatibility groups were able to mobilize SGI1 at a detectable level (transfer frequency <10(-9. In our collection, ESBL gene-carrying plasmids were mainly from the IncHI2 and I1 groups and thus were unable to mobilize SGI1. However, the horizontal transfer of SGI1 was shown to be specifically mediated by conjugative helper plasmids of the broad-host-range IncA/C incompatibility group. Several conjugative IncA/C MDR plasmids as well as the sequenced IncA/C reference plasmid pRA1 of 143,963 bp were shown to mobilize in trans SGI1 from a S. enterica donor to the Escherichia coli recipient strain. Depending on the IncA/C plasmid used, the conjugative transfer of SGI1 occurred at frequencies ranging from 10(-3 to 10(-6 transconjugants per donor. Of particular concern, some large IncA/C MDR plasmids carrying the extended-spectrum cephalosporinase bla(CMY-2 gene were shown to mobilize in trans SGI1. CONCLUSIONS/SIGNIFICANCE: The ability of the IncA/C MDR plasmid family to mobilize SGI1 could contribute to its spread by horizontal transfer among enteric pathogens. Moreover, the increasing prevalence of IncA/C plasmids in MDR S. enterica isolates worldwide has potential implications for the epidemic success of

  16. The Rhode Island Ocean Special Area Management Plan (Ocean SAMP)

    Energy Technology Data Exchange (ETDEWEB)

    Fugate, Grover J. [Univ. of Rhode Island, Kingston, RI (United States)

    2012-06-01

    In 2010, the University of Rhode Island (URI) secured $2,000,000 from the Rhode Island Office of Energy Resources (OER) to support research studies for the identification of preferred sites for offshore renewable energy development in Rhode Island’s offshore waters. This research will provide the Rhode Island Coastal Resources Management Council (CRMC) with sound technical information to assist in the siting of wind turbines in Rhode Island’s offshore waters. CRMC is the state agency with jurisdiction over development, preservation and restoration of Rhode Island’s coasts out to the three-mile limit, and is the state’s authority for federal consistency. With technical support from URI, CRMC is currently leading the implementation of the Rhode Island Ocean Special Area Management Plan (Ocean SAMP) with the purpose of developing policies and standards to guide the development of offshore renewable energy. The justification behind renewable energy development in Rhode Island includes diversifying the energy sources supplying electricity consumed in the state, stabilizing long-term energy prices, enhancing environmental quality – including the reduction of air pollutants and greenhouse gas emissions – reducing the state’s reliance on fossil fuels, and creating jobs in Rhode Island in the renewable energy sector.

  17. Secretory production of Aspergillus oryzae xylanase XynF1, xynF1 cDNA product, in the basidiomycete Coprinus cinereus.

    Science.gov (United States)

    Kikuchi, M; Kitamoto, N; Shishido, K

    2004-02-01

    The signal peptide of Aspergillus oryzae endo-(1,4)-beta-xylanase XynF1 contains a C-terminal serine-arginine that directs efficient secretion of the enzyme into the culture medium. In the basidiomycete Coprinus cinereus, however, there is little secretion of XynF1 into the culture medium. Modification of the C-terminal sequence of the signal peptide to lysine-arginine resulted in efficient secretion of C. cinereus XynF1, suggesting the presence of a KEX2-like protease in this fungus.

  18. Classication of Status of the Region on Java Island using C4.5, CHAID, and CART Methods

    Science.gov (United States)

    Syaraswati, R. A.; Slamet, I.; Winarno, B.

    2017-06-01

    The indicator of region economic success can be measured by economic growth, presented by value of Gross Regional Domestic Product (GRDP). Java island has the biggest GDP contribution toward the Indonesian government, but not all of the region gives equality contribution. The C4.5, CHAID, and CART methods can be used for classifying the status of the region with nonparametric approach. The C4.5 and CHAID methods are non-binary decision tree, meanwhile the CART methods is binary decision tree. The purposes of this paper are to know how the classification and to determine the factors that influence on classification of the region. The dependent variable is status of the region which is divided into four categories based on Klassen typology. The result shows factors that have the biggest contribution on classification of status of the region on Java island based on C4.5 method are economic growth rate, electricity, gas, and water sector, and area. The factors that have the biggest contribution based on CHAID method are growth rate, manufacturing sector, and electricity, gas, and water sector, while based on CART method are growth rate, manufacturing sector, and electricity, gas, and water sector.

  19. Escherichia coli Braun Lipoprotein (BLP) exhibits endotoxemia - like pathology in Swiss albino mice.

    Science.gov (United States)

    Lakshmikanth, Chikkamenahalli Lakshminarayana; Jacob, Shancy Petsel; Kudva, Avinash Kundadka; Latchoumycandane, Calivarathan; Yashaswini, Puttaraju Srikanta Murthy; Sumanth, Mosale Seetharam; Goncalves-de-Albuquerque, Cassiano F; Silva, Adriana R; Singh, Sridevi Annapurna; Castro-Faria-Neto, Hugo C; Prabhu, Sandeep Kumble; McIntyre, Thomas M; Marathe, Gopal Kedihithlu

    2016-10-04

    The endotoxin lipopolysaccharide (LPS) promotes sepsis, but bacterial peptides also promote inflammation leading to sepsis. We found, intraperitoneal administration of live or heat inactivated E. coli JE5505 lacking the abundant outer membrane protein, Braun lipoprotein (BLP), was less toxic than E. coli DH5α possessing BLP in Swiss albino mice. Injection of BLP free of LPS purified from E. coli DH5α induced massive infiltration of leukocytes in lungs and liver. BLP activated human polymorphonuclear cells (PMNs) ex vivo to adhere to denatured collagen in serum and polymyxin B independent fashion, a property distinct from LPS. Both LPS and BLP stimulated the synthesis of platelet activating factor (PAF), a potent lipid mediator, in human PMNs. In mouse macrophage cell line, RAW264.7, while both BLP and LPS similarly upregulated TNF-α and IL-1β mRNA; BLP was more potent in inducing cyclooxygenase-2 (COX-2) mRNA and protein expression. Peritoneal macrophages from TLR2-/- mice significantly reduced the production of TNF-α in response to BLP in contrast to macrophages from wild type mice. We conclude, BLP acting through TLR2, is a potent inducer of inflammation with a response profile both common and distinct from LPS. Hence, BLP mediated pathway may also be considered as an effective target against sepsis.

  20. Escherichia coli Braun Lipoprotein (BLP) exhibits endotoxemia – like pathology in Swiss albino mice

    Science.gov (United States)

    Lakshmikanth, Chikkamenahalli Lakshminarayana; Jacob, Shancy Petsel; Kudva, Avinash Kundadka; Latchoumycandane, Calivarathan; Yashaswini, Puttaraju Srikanta Murthy; Sumanth, Mosale Seetharam; Goncalves-de-Albuquerque, Cassiano F.; Silva, Adriana R.; Singh, Sridevi Annapurna; Castro-Faria-Neto, Hugo C.; Prabhu, Sandeep Kumble; McIntyre, Thomas M.; Marathe, Gopal Kedihithlu

    2016-01-01

    The endotoxin lipopolysaccharide (LPS) promotes sepsis, but bacterial peptides also promote inflammation leading to sepsis. We found, intraperitoneal administration of live or heat inactivated E. coli JE5505 lacking the abundant outer membrane protein, Braun lipoprotein (BLP), was less toxic than E. coli DH5α possessing BLP in Swiss albino mice. Injection of BLP free of LPS purified from E. coli DH5α induced massive infiltration of leukocytes in lungs and liver. BLP activated human polymorphonuclear cells (PMNs) ex vivo to adhere to denatured collagen in serum and polymyxin B independent fashion, a property distinct from LPS. Both LPS and BLP stimulated the synthesis of platelet activating factor (PAF), a potent lipid mediator, in human PMNs. In mouse macrophage cell line, RAW264.7, while both BLP and LPS similarly upregulated TNF-α and IL-1β mRNA; BLP was more potent in inducing cyclooxygenase-2 (COX-2) mRNA and protein expression. Peritoneal macrophages from TLR2−/− mice significantly reduced the production of TNF-α in response to BLP in contrast to macrophages from wild type mice. We conclude, BLP acting through TLR2, is a potent inducer of inflammation with a response profile both common and distinct from LPS. Hence, BLP mediated pathway may also be considered as an effective target against sepsis. PMID:27698491

  1. 46 CFR 154.625 - Design temperature below 0 °C (32 °F) and down to −165 °C (−265 °F).

    Science.gov (United States)

    2010-10-01

    ... LIQUEFIED GASES Design, Construction and Equipment Materials § 154.625 Design temperature below 0 °C (32 °F... 46 Shipping 5 2010-10-01 2010-10-01 false Design temperature below 0 °C (32 °F) and down to â165... process piping for a design temperature below 0 °C (32 °F) and down to −165 °C (−265 °F) must meet § 56.50...

  2. C-H and P-C(Ph) activation competitive processes caused by interaction with the solvate [cis-Pt(C6F5)2(thf)2].

    Science.gov (United States)

    Berenguer, Jesús R; Bernechea, María; Lalinde, Elena

    2007-06-21

    The study of the reaction between the ethylene [Pt(eta-H2C = CH2)(PPh3)2] or alkyne [Pt(eta2-HC [triple bond] CR)(PPh3)2] (R = SiMe3 1, Bu(t) 2) complexes with [cis-Pt(C6F5)2(thf)2] (thf = tetrahydrofuran) has enabled us to observe the existence of competitive processes between the activation of a P-C(Ph) bond on the PPh3 ligand, to give the binuclear derivative [cis-(C6F5)2Pt(mu-Ph)(mu-PPh2)Pt(PPh3)] 3, and the activation of a C-H bond of the unsaturated group, to give the corresponding (mu-hydride)(mu-vinyl) [cis, cis-(PPh3)2Pt(mu-H)(mu-1kappaC(alpha):eta2-CH = CH2)Pt(C6F5)2] 4 or (mu-hydride)(mu-alkynyl) [cis,cis-(PPh3)2Pt(mu-H)(mu-1kappaC(alpha):eta2-C [triple bond]CR)Pt(C6F5)2] (R = SiMe3 5, Bu(t) 6) compounds, respectively. The monitoring of these reactions by NMR spectroscopy has allowed us to detect several intermediates, and to propose a mechanism for the C-H bond activation. In addition, the structures of the (muo-hydride)(mu-alkynyl) complex 5 and the unprecedented (mu-hydride)(mu-vinyl) derivative 4 have been obtained by X-ray crystallographic analyses.

  3. Numerical modelling of micro-machining of f.c.c. single crystal: Influence of strain gradients

    KAUST Repository

    Demiral, Murat

    2014-11-01

    A micro-machining process becomes increasingly important with the continuous miniaturization of components used in various fields from military to civilian applications. To characterise underlying micromechanics, a 3D finite-element model of orthogonal micro-machining of f.c.c. single crystal copper was developed. The model was implemented in a commercial software ABAQUS/Explicit employing a user-defined subroutine VUMAT. Strain-gradient crystal-plasticity and conventional crystal-plasticity theories were used to demonstrate the influence of pre-existing and evolved strain gradients on the cutting process for different combinations of crystal orientations and cutting directions. Crown Copyright © 2014.

  4. 77 FR 28668 - Technical Standard Order (TSO)-C91a, Emergency Locator Transmitters (ELTs)

    Science.gov (United States)

    2012-05-15

    ... Technical Standard Order (TSO)-C91a, Emergency Locator Transmitter (ELT) Equipment. SUMMARY: This notice announces the FAA's cancellation of TSO-C91a, Emergency Locator Transmitter (ELT) Equipment. The effect of... December 1, 2012, must seek authorization for TSO-C126a, 406 MHz Emergency Locator Transmitter (ELT), or...

  5. Expression and characterization of Escherichia coli derived hepatitis C virus ARFP/F protein.

    Science.gov (United States)

    Baghbani-arani, F; Roohvand, F; Aghasadeghi, M R; Eidi, A; Amini, S; Motevalli, F; Sadat, S M; Memarnejadian, A; Khalili, G

    2012-01-01

    Genome of the hepatitis C virus (HCV) contains a long open reading frame encoding a polyprotein that is cleaved into 10 proteins. Recently, a novel, so called "ARFP/F", or "core+1", protein, which is expressed through a ribosomal frame shift within the capsid-coding sequence, has been described. Herein, to produce and characterize a recombinant form of this protein, the DNA sequence corresponding to the ARFP/F protein (amino acid 11-161) was amplified using a frame-shifted forward primer exploiting the capsid sequence of the 1b-subtype as a template. The amplicon was cloned into the pET-24a vector and expressed in different Escherichia coli strains. The expressed protein (mostly as insoluble inclusion bodies) was purified under denaturing conditions on a nickel-nitrilotriacetic acid (Ni-NTA) affinity column in a single step with a yield of 5 mg/L of culture media. After refolding steps, characterization of expressed ARFP/F was performed by SDS-PAGE and Western blot assay using specific antibodies. Antigenic properties of the protein were verified by ELISA using HCV-infected human sera and by its ability for a strong and specific interaction with sera of mice immunized with the peptide encoding a dominant ARFP/F B-cell epitope. The antigenicity plot revealed 3 major antigenic domains in the first half of the ARFP/F sequence. Immunization of BALB/c mice with the ARFP/F protein elicited high titers of IgG indicating the relevance of produced protein for induction of a humoral response. In conclusion, possibility of ARFP/F expression with a high yield and immunogenic potency of this protein in a mouse model have been demonstrated.

  6. The master activator of IncA/C conjugative plasmids stimulates genomic islands and multidrug resistance dissemination.

    Directory of Open Access Journals (Sweden)

    Nicolas Carraro

    2014-10-01

    Full Text Available Dissemination of antibiotic resistance genes occurs mostly by conjugation, which mediates DNA transfer between cells in direct contact. Conjugative plasmids of the IncA/C incompatibility group have become a substantial threat due to their broad host-range, the extended spectrum of antimicrobial resistance they confer, their prevalence in enteric bacteria and their very efficient spread by conjugation. However, their biology remains largely unexplored. Using the IncA/C conjugative plasmid pVCR94ΔX as a prototype, we have investigated the regulatory circuitry that governs IncA/C plasmids dissemination and found that the transcriptional activator complex AcaCD is essential for the expression of plasmid transfer genes. Using chromatin immunoprecipitation coupled with exonuclease digestion (ChIP-exo and RNA sequencing (RNA-seq approaches, we have identified the sequences recognized by AcaCD and characterized the AcaCD regulon. Data mining using the DNA motif recognized by AcaCD revealed potential AcaCD-binding sites upstream of genes involved in the intracellular mobility functions (recombination directionality factor and mobilization genes in two widespread classes of genomic islands (GIs phylogenetically unrelated to IncA/C plasmids. The first class, SGI1, confers and propagates multidrug resistance in Salmonella enterica and Proteus mirabilis, whereas MGIVmi1 in Vibrio mimicus belongs to a previously uncharacterized class of GIs. We have demonstrated that through expression of AcaCD, IncA/C plasmids specifically trigger the excision and mobilization of the GIs at high frequencies. This study provides new evidence of the considerable impact of IncA/C plasmids on bacterial genome plasticity through their own mobility and the mobilization of genomic islands.

  7. Effect of thermal cycling of SiC{sub f}/SiC composites on their mechanical properties

    Energy Technology Data Exchange (ETDEWEB)

    Udayakumar, A., E-mail: audayk@yahoo.com [Materials Science Division, Council of Scientific and Industrial Research – National Aerospace Laboratories, Bangalore-560 017 (India); Stalin, M.; Abhayalakshmi, M.B.; Hariharan, Ramya [Materials Science Division, Council of Scientific and Industrial Research – National Aerospace Laboratories, Bangalore-560 017 (India); Balasubramanian, M., E-mail: mbala@iitm.ac.in [Department of Metallurgical and Materials Engineering, Indian Institute of Technology Madras, Chennai-600 036 (India)

    2013-11-15

    SiC{sub f}/SiC composites are class of high temperature structural materials being developed for use in nuclear fusion and fission reactor systems because of their superior high temperature mechanical properties, low radiation damage and low induced radioactivity. Two types of 2D SiC{sub f}/SiC composites were made through isothermal and isobaric chemical vapor infiltration process using eight harness satin-woven ceramic-grades Nicalon™ fibers with boron nitride (BN) interface, namely: one with lower interface thickness and a second type with higher interface thickness. The BN interface was applied to the fiber prior to SiC matrix addition to modify the interfacial bond strength leading to better toughness and improved oxidation resistance. The density achieved was around 2.6 g/cc. The composite specimens were subjected to thermal cycling treatment using an in-house furnace. The mechanical properties such as tensile strength, fracture toughness and interfacial bond strength were also studied for all the composites before and after thermal cycling. It is seen from the results that both composites withstood thermal shocks and thermal cycling treatment. It was also concluded from the present work that good balance between load transfer and crack arresting was established.

  8. Effect of fiber architecture on mechanical behavior of SiC(f)/SiC composites

    Energy Technology Data Exchange (ETDEWEB)

    Singh, D.; Singh, J.P.; Sutaria, M.

    1997-01-01

    We evaluated mechanical properties (first matrix cracking stress, strength, and work-of-fracture) of Nicalon-fiber-reinforced silicon carbide matrix composites with three different fiber lay-up sequences (0{degrees}/20{degrees}/60{degrees}, 0{degrees}/40{degrees}/60{degrees}, and 0{degrees}/45{degrees}) at various temperatures from room to 1300{degrees}C. Up to 1200{degrees}C, ultimate strength and work-of-fracture for the 0{degrees}/40{degrees}/60{degrees} and 0{degrees}/45{degrees} composites increased, but then declined at 1300{degrees}C. The decreases were correlated to in-situ Nicalon fiber strength and fiber/matrix interface degradation. However, for the 0{degrees}/20{degrees}/60{degrees} composites, ultimate strength and work-of-fracture reached their a minima at 1200{degrees}C. These measured ultimate strengths at room and 1300{degrees}C were correlated to the predictions made with an analytical model and to in-situ fiber strength characteristics. The large difference in room-temperature ultimate strengths between the three sets of composites is attributed to the relative contributions of the off-axis fibers to the load-bearing capacity of each composite.

  9. Comparison of standardized uptake values measured on {sup 18}F-NaF PET/CT scans using three different tube current intensities

    Energy Technology Data Exchange (ETDEWEB)

    Valadares, Agnes Araujo; Woellner, Eduardo Bechtloff; Sapienza, Marcelo Tatit; Buchpiguel, Carlos Alberto, E-mail: agnesvaladares@me.com [Universidade de Sao Paulo (HC/FMUSP), Sao Paulo, SP (Brazil). Fac. de Medicina. Hospital das Clinicas; Duarte, Paulo Schiavom; Coura-Filho, George Barberio [Instituto do Cancer do Estado de Sao Paulo Octavio Frias de Oliveira (ICESP), Sao Paulo, SP (Brazil)

    2015-01-15

    Objective: to analyze standardized uptake values (SUVs) using three different tube current intensities for attenuation correction on {sup 18}FNaF PET/CT scans. Materials and methods: a total of 254 {sup 18}F-NaF PET/CT studies were analyzed using 10, 20 and 30 mAs. The SUVs were calculated in volumes of interest (VOIs) drawn on three skeletal regions, namely, right proximal humeral diaphysis (RH), right proximal femoral diaphysis (RF), and first lumbar vertebra (LV1) in a total of 712 VOIs. The analyses covered 675 regions classified as normal (236 RH, 232 RF, and 207 LV1). Results: mean SUV for each skeletal region was 3.8, 5.4 and 14.4 for RH, RF, and LV1, respectively. As the studies were grouped according to mAs value, the mean SUV values were 3.8, 3.9 and 3.7 for 10, 20 and 30 mAs, respectively, in the RH region; 5.4, 5.5 and 5.4 for 10, 20 and 30 mAs, respectively, in the RF region; 13.8, 14.9 and 14.5 for 10, 20 and 30 mAs, respectively, in the LV1 region. Conclusion: the three tube current values yielded similar results for SUV calculation. (author)

  10. Comparison of standardized uptake values measured on F-NaF PET/CT scans using three different tube current intensities.

    Science.gov (United States)

    Valadares, Agnes Araujo; Duarte, Paulo Schiavom; Woellner, Eduardo Bechtloff; Coura-Filho, George Barberio; Sapienza, Marcelo Tatit; Buchpiguel, Carlos Alberto

    2015-01-01

    To analyze standardized uptake values (SUVs) using three different tube current intensities for attenuation correction on (18)FNaF PET/CT scans. A total of 254 (18)F-NaF PET/CT studies were analyzed using 10, 20 and 30 mAs. The SUVs were calculated in volumes of interest (VOIs) drawn on three skeletal regions, namely, right proximal humeral diaphysis (RH), right proximal femoral diaphysis (RF), and first lumbar vertebra (LV1) in a total of 712 VOIs. The analyses covered 675 regions classified as normal (236 RH, 232 RF, and 207 LV1). Mean SUV for each skeletal region was 3.8, 5.4 and 14.4 for RH, RF, and LV1, respectively. As the studies were grouped according to mAs value, the mean SUV values were 3.8, 3.9 and 3.7 for 10, 20 and 30 mAs, respectively, in the RH region; 5.4, 5.5 and 5.4 for 10, 20 and 30 mAs, respectively, in the RF region; 13.8, 14.9 and 14.5 for 10, 20 and 30 mAs, respectively, in the LV1 region. The three tube current values yielded similar results for SUV calculation.

  11. Dark Matter Search Results from the PICO-60 C$_3$F$_8$ Bubble Chamber

    Energy Technology Data Exchange (ETDEWEB)

    Amole, C.; et al.

    2017-02-24

    New results are reported from the operation of the PICO-60 dark matter detector, a bubble chamber filled with 52 kg of C$_3$F$_8$ located in the SNOLAB underground laboratory. As in previous PICO bubble chambers, PICO-60 C$_3$F$_8$ exhibits excellent electron recoil and alpha decay rejection, and the observed multiple-scattering neutron rate indicates a single-scatter neutron background of less than 1 event per month. A blind analysis of an efficiency-corrected 1167-kg-day exposure at a 3.3-keV thermodynamic threshold reveals no single-scattering nuclear recoil candidates, consistent with the predicted background. These results set the most stringent direct-detection constraint to date on the WIMP-proton spin-dependent cross section at 3.4 $\\times$ 10$^{-41}$ cm$^2$ for a 30-GeV$\\thinspace$c$^{-2}$ WIMP, more than one order of magnitude improvement from previous PICO results.

  12. Effects of extrinsic point defects in phosphorene: B, C, N, O, and F adatoms

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Gaoxue, E-mail: gaoxuew@mtu.edu, E-mail: pandey@mtu.edu, E-mail: shashi.p.karna.civ@mail.mil; Pandey, Ravindra, E-mail: gaoxuew@mtu.edu, E-mail: pandey@mtu.edu, E-mail: shashi.p.karna.civ@mail.mil [Department of Physics, Michigan Technological University, Houghton, Michigan 49931 (United States); Karna, Shashi P., E-mail: gaoxuew@mtu.edu, E-mail: pandey@mtu.edu, E-mail: shashi.p.karna.civ@mail.mil [U.S. Army Research Laboratory, Weapons and Materials Research Directorate, ATTN: RDRL-WM, Aberdeen Proving Ground, Maryland 21005-5069 (United States)

    2015-04-27

    Phosphorene is emerging as a promising 2D semiconducting material with a direct band gap and high carrier mobility. In this paper, we examine the role of the extrinsic point defects including surface adatoms in modifying the electronic properties of phosphorene using density functional theory. The surface adatoms considered are B, C, N, O, and F with a [He] core electronic configuration. Our calculations show that B and C, with electronegativity close to P, prefer to break the sp{sup 3} bonds of phosphorene and reside at the interstitial sites in the 2D lattice by forming sp{sup 2} like bonds with the native atoms. On the other hand, N, O, and F, which are more electronegative than P, prefer the surface sites by attracting the lone pairs of phosphorene. B, N, and F adsorption will also introduce local magnetic moment to the lattice. Moreover, B, C, N, and F adatoms will modify the band gap of phosphorene, yielding metallic transverse tunneling characters. Oxygen does not modify the band gap of phosphorene, and a diode like tunneling behavior is observed. Our results therefore offer a possible route to tailor the electronic and magnetic properties of phosphorene by the adatom functionalization and provide the physical insights of the environmental sensitivity of phosphorene, which will be helpful to experimentalists in evaluating the performance and aging effects of phosphorene-based electronic devices.

  13. Changing the Introduction to Fighter Fundamentals Course for 21st Century F-15C Pilots

    Science.gov (United States)

    2016-01-01

    forty to forty-three days.13 For the purpose of this research, the focus will be on those students designated to fly the F-15C following completion...relatable in all fighter aircraft, with minor differences in syllabus focus. The courses are slightly different at all the training bases, but retain the...same training objectives and overall end state. The 435th Fighter Training Squadron and their syllabus , AETC Syllabus B/F-V5A-K dated July 2014

  14. A strategy for translating evidence into policy and practice to close the gap - developing essential service standards for Aboriginal and Torres Strait Islander cardiovascular care.

    Science.gov (United States)

    Brown, Alex; O'Shea, Rebekah L; Mott, Kathy; McBride, Katharine F; Lawson, Tony; Jennings, Garry L R

    2015-02-01

    The development and application of essential standards for cardiovascular care for Aboriginal and Torres Strait Islander people creates a strategic platform on which to systematically close the gap in the health outcomes and life expectancy between Aboriginal and Torres Strait Islander and non-Indigenous people in Australia. We outline six developmental stages that can be used to enhance the effective translation of evidence into practice that reduces life expectancy differentials. Focussing efforts where the biggest gain can be made; considering how to make a policy-relevant difference with an emphasis on translation into policy and practice; establishing a foundation for action by engaging with stakeholders throughout the process; developing a framework to guide action; drafting policy-relevant and framework-appropriate essential service standards; and defining standards that help policy decision makers achieve current priority policy targets. Copyright © 2014 Australian and New Zealand Society of Cardiac and Thoracic Surgeons (ANZSCTS) and the Cardiac Society of Australia and New Zealand (CSANZ). Published by Elsevier B.V. All rights reserved.

  15. Search for Physics Beyond the Standard Model via Positron Polarization Measurements with Polarized $ ^{17} $F.

    CERN Multimedia

    Versyck, S

    2002-01-01

    This proposal aims at measuring the longitudinal polarization of positrons emitted from polarized $^{17} $F~nuclei. The experiment will have a comparable sensitivity to possible right-handed current contributions in the weak interaction as the experiment which was recently carried out with $ ^{107} $In in Louvain-la-Neuve, but will provide a more stringent limit due to the fact that, since $ ^{17} $F decays through a superallowed $\\beta$ -transition, the recoil-order corrections to the allowed approximation can be taken into account very precisely. Furthermore, because $ ^{17} $F decays via a mixed Fermi/Gamow-Teller $\\beta$ -transition, this experiment will also yield a new limit on possible scalar contributions to the weak interaction. While the $^{17}$F beam is being developed, part of the beamtime was used to perform a similar experiment with $^{118}$ Sb. As this isotope decays via a pure GT $\\beta$ -transition, this experiment will yield new limits on the possible presence of both right-handed and tensor...

  16. 12 CFR Appendix F to Part 225 - Interagency Guidelines Establishing Information Security Standards

    Science.gov (United States)

    2010-01-01

    ... on behalf of bank holding companies and their nonbank subsidiaries or affiliates (except brokers... holding company. f. Subsidiary means any company controlled by a bank holding company, except a broker... information security program in light of any relevant changes in technology, the sensitivity of its customer...

  17. Mass transfer in a 1370 C (2500 F) lithium thermal convection loop

    Science.gov (United States)

    Scheuermann, C. M.

    1974-01-01

    Experimental results from a test to evaluate interstitial element mass transfer effects on T-111, ASTAR 811C, and ASTAR 1211C after 5000 hours in flowing lithium at 1370 C (2500 F) are presented. No gross corrosion effects were observed. However, hafnium and nitrogen transfer to cooler regions within the loop were noted. Oxygen was in general removed from test specimens, but there was no evidence to indicate that it was a major factor in the mass transfer process. Carbon and hydrogen transfer were not detected.

  18. Characterization of cetuximab F{sub c/2} dimers by off-line CZE-MS

    Energy Technology Data Exchange (ETDEWEB)

    François, Yannis-Nicolas, E-mail: yfrancois@unistra.fr [Laboratoire de Spectrométrie de Masse des Interactions et des Systèmes (LSMIS), UDS-CNRS UMR 7140, Université de Strasbourg, Strasbourg (France); Biacchi, Michael; Said, Nassur; Renard, Charly [Laboratoire de Spectrométrie de Masse des Interactions et des Systèmes (LSMIS), UDS-CNRS UMR 7140, Université de Strasbourg, Strasbourg (France); Beck, Alain [Centre d' immunologie Pierre Fabre, Saint-Julien-en-Genevois (France); Gahoual, Rabah [Laboratoire de Spectrométrie de Masse des Interactions et des Systèmes (LSMIS), UDS-CNRS UMR 7140, Université de Strasbourg, Strasbourg (France); Laboratory of Bioanalytical Chemistry and Spectroscopy, Vrije Universiteit, Amsterdam (Netherlands); Leize-Wagner, Emmanuelle [Laboratoire de Spectrométrie de Masse des Interactions et des Systèmes (LSMIS), UDS-CNRS UMR 7140, Université de Strasbourg, Strasbourg (France)

    2016-02-18

    Monoclonal antibody (mAb) therapeutics attract the largest concern due to their strong therapeutic potency and specificity. The Fc region of mAbs is common to many new biotherapeutics as biosimilar, antibody drug conjugate or fusion protein. Fc region has consequences for Fc-mediated effector functions that might be desirable for therapeutic applications. As a consequence, there is a continuous need for improvement of analytical methods to enable fast and accurate characterization of biotherapeutics. Capillary zone electrophoresis-Mass spectrometry couplings (CZE-MS) appear really attractive methods for the characterization of biological samples. In this report, we used CZE-MS systems developed in house and native MS infusion to allow precise middle-up characterization of F{sub c/2} variant of cetuximab. Molecular weights were measured for three F{sub c/2} charge variants detected in the CZE separation of cetuximab subunits. Two F{sub c/2} C-terminal lysine variants were identified and separated. As the aim is to understand the presence of three peaks in the CZE separation for two F{sub c/2} subunits, we developed a strategy using CZE-UV/MALDI-MS and CZE-UV/ESI-MS to evaluate the role of N-glycosylation and C-terminal lysine truncation on the CZE separation. The chemical structure of N-glycosylation expressed on the Fc region of cetuximab does not influence CZE separation while C-terminal lysine is significantly influencing separation. In addition, native MS infusion demonstrated the characterization of F{sub c/2} dimers at pH 5.7 and 6.8 and the first separation of these dimers using CZE-MS. - Highlights: • We confirm the power of off-line CE/MS coupling for the separation of mAb isoforms. • We demonstrate the role of C-terminal lysine truncation in the separation process. • We demonstrate the presence of non-covalent interactions between Fc/2 subunit. • We identify Fc/2 homo- and heterodimers.

  19. Materials for advanced ultrasupercritical steam turbines

    Energy Technology Data Exchange (ETDEWEB)

    Purgert, Robert [Energy Industries Of Ohio Inc., Independence, OH (United States); Shingledecker, John [Energy Industries Of Ohio Inc., Independence, OH (United States); Saha, Deepak [Energy Industries Of Ohio Inc., Independence, OH (United States); Thangirala, Mani [Energy Industries Of Ohio Inc., Independence, OH (United States); Booras, George [Energy Industries Of Ohio Inc., Independence, OH (United States); Powers, John [Energy Industries Of Ohio Inc., Independence, OH (United States); Riley, Colin [Energy Industries Of Ohio Inc., Independence, OH (United States); Hendrix, Howard [Energy Industries Of Ohio Inc., Independence, OH (United States)

    2015-12-01

    The U.S. Department of Energy (DOE) and the Ohio Coal Development Office (OCDO) have sponsored a project aimed at identifying, evaluating, and qualifying the materials needed for the construction of the critical components of coal-fired power plants capable of operating at much higher efficiencies than the current generation of supercritical plants. This increased efficiency is expected to be achieved principally through the use of advanced ultrasupercritical (A-USC) steam conditions. A limiting factor in this can be the materials of construction for boilers and for steam turbines. The overall project goal is to assess/develop materials technology that will enable achieving turbine throttle steam conditions of 760°C (1400°F)/35MPa (5000 psi). This final technical report covers the research completed by the General Electric Company (GE) and Electric Power Research Institute (EPRI), with support from Oak Ridge National Laboratory (ORNL) and the National Energy Technology Laboratory (NETL) – Albany Research Center, to develop the A-USC steam turbine materials technology to meet the overall project goals. Specifically, this report summarizes the industrial scale-up and materials property database development for non-welded rotors (disc forgings), buckets (blades), bolting, castings (needed for casing and valve bodies), casting weld repair, and casting to pipe welding. Additionally, the report provides an engineering and economic assessment of an A-USC power plant without and with partial carbon capture and storage. This research project successfully demonstrated the materials technology at a sufficient scale and with corresponding materials property data to enable the design of an A-USC steam turbine. The key accomplishments included the development of a triple-melt and forged Haynes 282 disc for bolted rotor construction, long-term property development for Nimonic 105 for blading and bolting, successful scale-up of Haynes 282 and Nimonic 263 castings using

  20. Comparative Global Gene Expression Profiles of Wild-Type Yersinia pestis CO92 and Its Braun Lipoprotein Mutant at Flea and Human Body Temperatures

    Directory of Open Access Journals (Sweden)

    Cristi L. Galindo

    2010-01-01

    Full Text Available Braun/murein lipoprotein (Lpp is involved in inflammatory responses and septic shock. We previously characterized a Δlpp mutant of Yersinia pestis CO92 and found that this mutant was defective in surviving in macrophages and was attenuated in a mouse inhalation model of plague when compared to the highly virulent wild-type (WT bacterium. We performed global transcriptional profiling of WT Y. pestis and its Δlpp mutant using microarrays. The organisms were cultured at 26 and 37 degrees Celsius to simulate the flea vector and mammalian host environments, respectively. Our data revealed vastly different effects of lpp mutation on the transcriptomes of Y. pestis grown at 37 versus 26C. While the absence of Lpp resulted mainly in the downregulation of metabolic genes at 26C, the Y. pestis Δlpp mutant cultured at 37C exhibited profound alterations in stress response and virulence genes, compared to WT bacteria. We investigated one of the stress-related genes (htrA downregulated in the Δlpp mutant relative to WT Y. pestis. Indeed, complementation of the Δlpp mutant with the htrA gene restored intracellular survival of the Y. pestis Δlpp mutant. Our results support a role for Lpp in Y. pestis adaptation to the host environment, possibly via transcriptional activation of htrA.

  1. 13C NMR and ESR Characterization of Humic Substances Isolated from Soils of Two Siberian Arctic Islands

    Directory of Open Access Journals (Sweden)

    E. Abakumov

    2015-01-01

    Full Text Available Humic acids (HAs and fulvic acids (FAs of two Polar soils were investigated by 13C NMR and ESR spectroscopies, investigating the degree of humification and the molecular structure. One soil, from Bolshoi Lyakhovsky Island, contains two humus horizons: modern and buried. The other soil, from Wrangel Island, had only one modern humus horizon. The HAs and FAs of the two soils investigated show essential differences. The HAs show fewer oxygen-containing groups in comparison with the FAs, whereas the degree of aromaticity is two or three times higher in the HAs. The 13C NMR data also show that HAs are very different from FAs in terms of their molecular composition and hydrophobicity. Humification in the Arctic is limited by the very low content of lignin-derived compounds, due to the restricted vascular flora. As a result, the HAs, isolated from Polar soils, are more similar to the corresponding FAs than to the typical HAs of temperate soils. This was confirmed by ESR data, which show similar levels of free radical concentration for HAs and FAs and are related to the low level of aromaticity of both materials investigated. Apparently, the humification process in the soils of Polar Arctic deserts is in an initial stage.

  2. Validation of standard ASTM F2732 and comparison with ISO 11079 with respect to comfort temperature ratings for cold protective clothing.

    Science.gov (United States)

    Gao, Chuansi; Lin, Li-Yen; Halder, Amitava; Kuklane, Kalev; Holmér, Ingvar

    2015-01-01

    American standard ASTM F2732 estimates the lowest environmental temperature for thermal comfort for cold weather protective clothing. International standard ISO 11079 serves the same purpose but expresses cold stress in terms of required clothing insulation for a given cold climate. The objective of this study was to validate and compare the temperature ratings using human subject tests at two levels of metabolic rates (2 and 4 MET corresponding to 116.4 and 232.8 W/m(2)). Nine young and healthy male subjects participated in the cold exposure at 3.4 and -30.6 °C. The results showed that both standards predict similar temperature ratings for an intrinsic clothing insulation of 1.89 clo and for 2 MET activity. The predicted temperature rating for 2 MET activity is consistent with test subjects' thermophysiological responses, perceived thermal sensation and thermal comfort. For 4 MET activity, however, the whole body responses were on the cold side, particularly the responses of the extremities. ASTM F2732 is also limited due to its omission and simplification of three climatic variables (air velocity, radiant temperature and relative humidity) and exposure time in the cold which are of practical importance. Copyright © 2014 Elsevier Ltd and The Ergonomics Society. All rights reserved.

  3. Rekonfigurationstechniken und Anwendungsgebiete für ein programmierbares Gm-C Analog-Filter

    Directory of Open Access Journals (Sweden)

    J. Becker

    2006-01-01

    Full Text Available FPAAs (Field Programmable Analog Arrays erlauben es, analoge Signalübertragungsfunktionen auf Hardware abzubilden, die von veränderbaren digitalen Konfigurationsdaten abhängen. Sowohl für das Design von Filterstrukturen auf Systemebene als auch für die genaue Simulation ihrer analogen Übertragungsfunktion auf Transistorebene ist es dabei notwendig, die entsprechenden Konfigurationsdaten einzugeben bevor die Phasen/Betragsanalyse durchgeführt werden kann. Die vorliegende Arbeit stellt ein graphisches Entwurfsprogramm zur Instantiierung von analogen Filtern für ein FPAA mit 17 gm-C Blöcken vor. Es wird über erste Simulationsergebnisse berichtet, die die Machbarkeit mit Eckfrequenzen bis zu hundert Mhz bestätigen. Simulierte Übertragungsfunktionen von grundlegenden Bausteinen werden mit der Theorie verglichen und zu einer exemplarischen Instantiierung eines Butterworth-Filters der vierten Ordnung weitergeführt.

  4. Duration Test Report for the Entegrity EW50 Wind Turbine

    Energy Technology Data Exchange (ETDEWEB)

    Smith, J.; Huskey, A.; Jager, D.; Hur, J.

    2012-12-01

    This report summarizes the results of a duration test that NREL conducted on the Entegrity EW50 wind turbine. This test was conducted in accordance with the International Electrotechnical Commissions' (IEC) standard, Wind Turbine Generator System Part 2: Design requirements for small wind turbines, IEC 61400-2 Ed.2.0, 2006-03.

  5. C-Brick: A New Standard for Assembly of Biological Parts Using Cpf1.

    Science.gov (United States)

    Li, Shi-Yuan; Zhao, Guo-Ping; Wang, Jin

    2016-12-16

    So far, several DNA assembly standards have been developed, enabling scientists to conveniently share and modify characterized DNA parts. However, a majority of the restriction endonucleases used in these standards bear short recognition sites (e.g., 6 bps in BioBrick standard), which are widely distributed and need to be removed before further construction, causing much inconvenience. Although homing endonucleases, which recognize long DNA sequences, can be used for DNA assembly (e.g., iBrick standard), long scars will be left between parts, limiting their application. Here, we introduce a new DNA assembly standard, namely C-Brick, which employs the newly identified class 2 type V CRISPR-Cas systems protein Cpf1 endonuclease. C-Brick integrates both advantages of long recognition sites and short scars. With C-Brick standard, three chromoprotein cassettes were assembled and further expressed in Escherichia coli, producing colorful pigments. Moreover, C-Brick standard is also partially compatible with the BglBrick and BioBrick standards.

  6. 24 CFR Appendix II to Subpart C of... - Development of Standards; Calculation Methods

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Development of Standards; Calculation Methods II Appendix II to Subpart C of Part 51 Housing and Urban Development Office of the Secretary, Department of Housing and Urban Development ENVIRONMENTAL CRITERIA AND STANDARDS Siting of HUD...

  7. Sofosbuvir-based treatment of hepatitis C with severe fibrosis (METAVIR F3/F4) after liver transplantation.

    Science.gov (United States)

    Dumortier, Jérôme; Leroy, Vincent; Duvoux, Christophe; de Ledinghen, Victor; Francoz, Claire; Houssel-Debry, Pauline; Radenne, Sylvie; d'Alteroche, Louis; Fougerou-Leurent, Claire; Canva, Valérie; di Martino, Vincent; Conti, Filomena; Kamar, Nassim; Moreno, Christophe; Lebray, Pascal; Tran, Albert; Besch, Camille; Diallo, Alpha; Rohel, Alexandra; Rossignol, Emilie; Abergel, Armand; Botta-Fridlund, Danielle; Coilly, Audrey; Samuel, Didier; Duclos-Vallée, Jean-Charles; Pageaux, Georges-Philippe

    2016-10-01

    Recurrence of hepatitis C virus (HCV) after liver transplantation (LT) can rapidly lead to liver graft cirrhosis and, therefore, graft failure and retransplantation or death. The aim of the present study was to assess efficacy and tolerance of sofosbuvir (SOF)-based regimens for the treatment of HCV recurrence in patients with severe fibrosis after LT. The Compassionate Use of Protease Inhibitors in Viral C Liver Transplantation (CULPIT) study is a prospective multicenter cohort including patients with HCV recurrence following LT treated with second generation direct antivirals. The present study focused on patients included between October 2013 and November 2014 and diagnosed with HCV recurrence and liver graft extensive fibrosis (METAVIR F3/F4). A SOF-based regimen was administered to 125 patients fulfilling inclusion criteria. The median delay from LT was 95.9 ± 69.6 months. The characteristics of patients were as follows: mean age, 59.4 ± 9.0 years; 78.4% male; infected by HCV genotype 1: 78.2%, mean HCV RNA: 6.1 ± 1.0 log10 IU/mL. Eighty patients had failed previous post-LT antiviral therapy (64.0%) including triple therapy with first generation protease inhibitors in 19 (15.2%) patients. The main combination regimen was SOF/daclatasvir (73.6%). Ribavirin was used in 60 patients. Sustained virological response 12 weeks after treatment was 92.8% (on an intention-to-treat basis); 7 patients with virological failure were observed. Serious adverse events occurred in 25.6% of the patients during antiviral treatment. During antiviral treatment and follow-up, 3 patients were retransplanted and 4 patients died. In conclusion, SOF-based antiviral treatment shows very promising results in patients with HCV recurrence and severe fibrosis after LT. Liver Transplantation 22 1367-1378 2016 AASLD. © 2016 by the American Association for the Study of Liver Diseases.

  8. 18 F-FDG PET standard uptake values of the normal pons in children: establishing a reference value for diffuse intrinsic pontine glioma.

    Science.gov (United States)

    Jansen, Marc H A; Kloet, Reina W; van Vuurden, Dannis G; Veldhuijzen van Zanten, Sophie Em; Witte, Birgit I; Goldman, Serge; Vandertop, W Peter; Comans, Emile Fi; Hoekstra, Otto S; Boellaard, Ronald; Kaspers, Gert-Jan Jl

    2014-01-28

    Positron emission tomography (PET) scanning with [18 F]fluorodeoxyglucose (18 F-FDG) is a useful diagnostic and prediction tool in brain tumors, but its value in childhood diffuse intrinsic pontine glioma (DIPG) is still unclear. For interpretation of 18 F-FDG PET results in DIPG, uptake values of the normal pons of children of increasing ages are mandatory. The aim of this study was to determine 18 F-FDG standard uptake value ratios (SUVr) of the normal pons and to compare these to those of DIPG. We studied 36 subjects with a normal, non-affected pons (aged 5 to 23 years) and 6 patients with DIPG (aged 4 to 17 years) who underwent 18 F-FDG PET scanning. Magnetic resonance imaging (MRI) was co-registered to define the regions of interest. SUVr and SUVrmax for the pons/cerebellum (SUVrp/c) and the pons/occipital lobe (SUVrp/o) were calculated. Independent-samples t tests and Mann-Whitney U tests were used to compare the mean SUVr and Pearson's test for correlations. For the normal pons, mean SUVrp/c and SUVrp/o were 0.65 (±0.054) and 0.51 (±0.056), respectively. No significant correlations were found between the SUVr of the normal pons and sex, age, nor pontine volume. A modest but statistically significant correlation was found between SUVr and post-injection time acquisition timing. For DIPG, mean SUVrp/c and SUVrp/o were 0.74 (±0.20) and 0.65 (±0.30), respectively, while mean SUVrp(max)/c and SUVrp(max)/o were 1.95 (±0.48) and 1.81 (±0.20), respectively. The SUVr of the unaffected pons are strikingly constant between children, irrespective of sex and age, and can therefore be well used as a reference value for 18 F-FDG PET studies in DIPG.

  9. Component Test Facility (Comtest) Phase 1 Engineering For 760°C (1400°F) Advanced Ultrasupercritical (A-USC) Steam Generator Development

    Energy Technology Data Exchange (ETDEWEB)

    Weitzel, Paul [Babcock & Wilcox Power Generation Group, Inc., Barberton, OH (United States)

    2016-05-13

    The Babcock & Wilcox Company (B&W) performed a Pre-Front End Engineering Design (Pre-FEED) of an A-USC steam superheater for a proposed component test program achieving 760°C (1400°F) steam temperature. This would lead to follow-on work in a Phase 2 and Phase 3 that would involve detail design, manufacturing, construction and operation of the ComTest. Phase 1 results have provided the engineering data necessary for proceeding to the next phase of ComTest. The steam generator superheater would subsequently supply the steam to an A-USC prototype intermediate pressure steam turbine. The ComTest program is important in that it will place functioning A-USC components in operation and in coordinated boiler and turbine service. It is also important to introduce the power plant operation and maintenance personnel to the level of skills required and provide the first background experience with hands-on training. The project will provide a means to exercise the complete supply chain events required in order to practice and perfect the process for A-USC power plant design, supply, manufacture, construction, commissioning, operation and maintenance. Representative participants will then be able to transfer knowledge and recommendations to the industry. ComTest is conceived in the manner of using a separate standalone plant facility that will not jeopardize the host facility or suffer from conflicting requirements in the host plant’s mission that could sacrifice the nickel alloy components and not achieve the testing goals. ComTest will utilize smaller quantities of the expensive materials and reduce the risk in the first operational practice for A-USC technology in the United States. Components at suitable scale in ComTest provide more assurance before putting them into practice in the full size A-USC demonstration plant.

  10. Electronic properties of CaF sub 2 nanodimensional islands on Si(0 0 1) An MDS and UPS study

    CERN Document Server

    Pasquali, L; Sokolov, N; Selvaggi, G; D'Addato, S; Nannarone, S

    2002-01-01

    The joint use of metastable deexcitation spectroscopy and angle resolved ultraviolet photoemission gives a valuable contribution to the comprehension of the physical-chemical reactions occurring during the formation of an interface between different materials. This approach has been applied to study the evolution of the surface valence band of CaF sub 2 deposited on Si(0 0 1) at different temperatures. Under suitable growth conditions, CaF sub 2 nanostructures of different shape and size can be obtained. Information regarding the chemical reactions taking place within the first deposited layer and the dependence of the electronic properties on film thickness was derived.

  11. Swelling behaviour and TEM studies of SiC f/SiC composites after fusion relevant helium implantation

    Science.gov (United States)

    Scholz, H. W.; Frias Rebelo, A. J.; Rickerby, D. G.; Krogul, P.; Lee, W. E.; Evans, J. H.; Fenici, P.

    1998-10-01

    Helium implantation was carried out on SiC f/SiC (CVI) composites up to doses of 2500 appm, at temperatures of 1175 ± 50 K. In this paper the swelling behaviour of the implanted bending bars is reported. A significant differential swelling effect after the α-implantation was evidenced by the matrix jutting out with respect to the fibre ends, at the side surfaces of the implanted zone. A similar fibre shrinkage together with slight expansion of the matrix was already reported for neutron irradiated materials. However, after α-implantation this effect is enhanced by an increased swelling of the β-SiC matrix. These data are discussed in relation to microstructural observations by Transmission Electron Microscopy.

  12. Continuous monitoring of the C isotope composition of CO_{2}-rich subsurface degassing at Tenerife, Canary Islands

    Science.gov (United States)

    Melián, Gladys; Asensio-Ramos, María; Padrón, Eleazar; Barrancos, José; Hernández, Pedro A.; Pérez, Nemesio M.

    2017-04-01

    Tenerife is the largest island of the Canarian archipelago and several volcanic eruptions have occurred in the last 500 years, the last one in 1909. The main volcano-tectonic features of Tenerife Island are three main volcano-tectonic rifts trending N-E, N-W and N-S where, at the interception center is located Las Cañadas caldera and the stratovolcano Teide-Pico Viejo. Due to the approximately 1,500 wells and water galleries (1650 km) drilled during the last 150 years tapping the island's volcanic aquifer at different depths, Tenerife is a unique natural-scale laboratory for hydrological studies in oceanic volcanic islands. Ground waters are mainly Na+-HCO3- water type, mainly due to the continuous volcanic CO2 supply from the volcanic-hydrothermal system. A signi?cant number of these galleries show a CO2-rich inner atmosphere, and gas bubbling has also been detected inside some galleries. Since 2002, an automatic geochemical station installed at the entrance of the horizontal drilling "Fuente del Valle" (TFE02 station), Arona, Tenerife, measures the activities of 222Rn and 220Rn in the gas discharged from a CO2-rich gas bubbling spot located at 2.850 m depth. Interesting variations were recorded in the 222Rn/220Rn ratio after the period of 2004 anomalous seismicity and it has been demonstrated that this is a good control spot for volcanic surveillance (Pérez et al., 2007). Thus, in November 2016, a new type of laser based isotopic analyzer, a DeltaRayTM (Thermo Fisher Scientific) was installed in the TFE02 station to measure δ13C(CO2) directly in the gas discharged from the water. The gas, collected by means of an inverted funnel, is pumped (3 L min-1) towards the gallery entrance, where the instrumentation is located, through a polyamide pipe. During the study period the recorded data show a range of δ13C(CO2) from -6.2 to -4.2‰ vs. VPDB, with an average value of -5.1‰Ṫhese values are comparable to those ones measured in the gas sampled directly at the

  13. Preliminary study of 11C-choline PET/CT for T staging of locally advanced nasopharyngeal carcinoma: comparison with 18F-FDG PET/CT.

    Science.gov (United States)

    Wu, Hu-bing; Wang, Quan-shi; Wang, Ming-fang; Zhen, Xiaokang; Zhou, Wen-lan; Li, Hong-sheng

    2011-03-01

    Evaluation of nasopharyngeal carcinoma (NPC) using (18)F-FDG PET/CT is limited by the intense physiologic uptake of (18)F-FDG in the brain. We attempted to improve detection of intracranial tumor invasion (including better delineation of invasion near the skull base) in locally advanced NPC using(11)C-choline PET/CT. Fifteen patients with newly diagnosed or recurrent locally advanced NPC were enrolled in the study. (18)F-FDG and (11)C-choline PET/CT was performed on all patients. PET/CT images obtained using the 2 tracers were compared using both maximum standardized uptake value (SUVmax) and tumor-to-brain (T/B) ratios. All patients were followed up for more than 1 y. The sensitivity of (18)F-FDG PET/CT in detecting locally advanced NPC was 86.6%, compared with a 100% sensitivity for (11)C-choline PET/CT (t = 2.143, P = 0.483). The SUVmax of lesions detected was higher using (18)F-FDG than using (11)C-choline (12.81 ± 5.00 vs. 6.84 ± 2.76, t = 6.416, P 18)F-FDG (18.62 ± 7.95 vs. 1.38 ± 0.59, t = 8.801, P 18)F-FDG PET/CT, (11)C-choline PET/CT improved the delineation of intracranial invasion in 6 of 12 patients (χ(2) = 8.00, P = 0.014), skull base invasion in 4 of 14 patients, and orbital invasion in 3 of 3 patients. (11)C-choline can improve the quality of PET/CT in the T staging of NPC.

  14. Toxicology and carcinogenesis studies of propargyl alcohol (CAS No. 107-19-7) in F344/N rats and B6C3F1 mice (inhalation studies).

    Science.gov (United States)

    2008-09-01

    Propargyl alcohol is a commercially available acetylenic primary alcohol. It is also a by-product in the industrial synthesis of butynediol from acetylene and formaldehyde with copper acetylide as catalyst. Propargyl alcohol is used as a reactant/chemical intermediate, pharmaceutical intermediate, agricultural chemical intermediate, soil fumigant, corrosion inhibitor, solvent stabilizer, and polymer modifier. It has also been used to prevent the hydrogen embrittlement of steel. Propargyl alcohol was nominated by the National Cancer Institute for study because of the potential for human exposure in occupational settings through inhalation and dermal contact. Male and female F344/N rats and B6C3F1 mice were exposed to propargyl alcohol (greater than 99% pure) by inhalation for 2 weeks, 3 months, or 2 years. Genetic toxicology studies were conducted in Salmonella typhimurium and mouse peripheral blood erythrocytes. 2-WEEK STUDY IN RATS: Groups of five male and five female rats were exposed to propargyl alcohol vapor at concentrations of 0, 31.3, 62.5, 125, 250, or 500 ppm, 6 hours plus T(90 )(12 minutes) per day, 5 days per week for 16 days. All males exposed to 125 ppm or greater and all females exposed to 250 or 500 ppm died by the end of day 3 of the study, and one 125 ppm female died on day 5. Mean body weights were significantly decreased in 62.5 ppm males and 125 ppm females. Clinical findings in the 125 and 250 ppm groups included lethargy, ataxia, abnormal breathing, and nasal/eye discharge. Right kidney weights of 62.5 and 125 ppm females and liver weights of 125 ppm females were significantly greater than those of the chamber controls. All 250 and 500 ppm males and females had moderate to marked periportal necrosis, congestion, and erythrophagocytosis of the liver. 2-WEEK STUDY IN MICE: Groups of five male and five female mice were exposed to propargyl alcohol vapor at concentrations of 0, 31.3, 62.5, 125, 250, or 500 ppm, 6 hours plus T(90) (12 minutes) per

  15. Razões para a falta de rendimento esportivo do Comercial F.C. Reasons for the lack of sports performance of Comercial F.C.

    Directory of Open Access Journals (Sweden)

    Cesar Machado Carvalho

    2012-04-01

    Full Text Available The international football, according to the report of the Plan for Modernization of the Brazilian Football FGV (2000 annual turnover of approximately $ 250 billion, while Brazil represents only 1% of the total. The Commercial F. C. headquartered in the city of Ribeirão Preto (SP, had its poly auctioned sports stadium partially forbidden for 23 years and not disputed the series A1, A3series being relegated to the Campeonato Paulista in 2009. This study aimed to identify those factors that hinder sports performance of the Commercial F. C., to do so, we studied its history, its relations with the government and legislation, market performance, partnerships established, administrative structures and results in the tournaments played between 2007 and 2008 to discuss their management problems. The methods used were research-explanatory and qualitative semi-structured interview to build a case study. We conclude that the gap between the formal structure and practice of members of the answers as a key element in the absence of the club's sports performance. O futebol internacional, segundo o relatório do Plano de Modernização do Futebol Brasileiro da FGV (2000, movimenta anualmente cerca de 250 bilhões de dólares, sendo que o Brasil participa com apenas 1% desse total. O Comercial F. C., sediado na Cidade de  Ribeirão Preto (SP, teve seu poliesportivo leiloado, estádio parcialmente interditado, e, há 23 anos, não disputava a série A1, sendo rebaixado para série A3 no Campeonato Paulista, em 2009. Este trabalho buscou identificar quais são os fatores que dificultam o rendimento esportivo do Comercial F. C., para tanto, foi estudada sua história, suas relações com o governo, sua legislação, seu mercado de atuação, suas parcerias realizadas, suas estruturas administrativas e seus  resultados  nos campeonatos disputados entre 2007 e 2008, a fim de discorrer

  16. Leonardsenite, MgAlF5(H2O)2, a new mineral species from Eldfell Volcano, Heimaey Island, Iceland

    DEFF Research Database (Denmark)

    Mitolo, Donatella; Garavelli, Anna; Balic Zunic, Tonci

    2013-01-01

    Leonardsenite (IMA2011-059), with ideal formula MgAlF5(H2O)(2), is a new fumarole mineral from Eldfell volcano, Iceland. It has also been found in volcanic encrustations from the Hekla crater, Iceland. The mineral forms a soft and friable mass of white crystals up to 20 mu m in length. The streak...

  17. Floral and Seed Variability Patterns among Ethiopian Mustard (B. carinata A. Braun of East Africa

    Directory of Open Access Journals (Sweden)

    Adeniji, OT.

    2012-01-01

    Full Text Available In East Africa, Ethiopian mustard (Brassica carinata A. Braun is cultivated primarily for its leaves, but in Ethiopia preference is high for oil in the seed. Dual purpose importance of the seeds for planting and for oil suggests the need to improve seed production efficiency through understanding variation pattern for floral morphology and seed characters. We investigated genetic diversity and correlations for floral and seed characteristics among 14 accessions of Ethiopian mustard to improve seed set and yield. Field trials were conducted during 2008 and 2009; flowers were examined for short stamen height, long stamen height, pistil height, and silliqua for seed weight, seeds/silliqua and silliqua/plant. Results were largely consistent between years, indicating that the variation measured was mainly controlled by genetic factors. High genetic variation for seed characters and reproductive phenology among the accessions was noted. The number of days to appearance of flowers showed high discriminatory ability among the accessions. A wide continuous variation was observed among accessions for anther-stigma separation. Accessions 1, 3 and 14 were identified as early flowering. A significant and positive correlation coefficient between short stamen height and seed weight indicated a substantial complementation among these characters for seed yield improvement. The short stamen height is a good indicator for selection in favour of seed commercialization and indices for selection of pollen parent for seed yield improvement. Accessions 5, 7, 14, 16 and 22 are best for multiple characters and are recommended for seed production for any of the seasons in Arusha, Tanzania.

  18. Agronomic performance for biodiesel production potential of Brassica carinata A. Braun in Mediterranean marginal areas

    Directory of Open Access Journals (Sweden)

    Francesco Montemurro

    2016-03-01

    Full Text Available Brassicaceae are promising oil feedstock for cultivation in centralsouthern Italy. Therefore, a two-year investigation on Brassica carinata A. Braun (cv. CT 204 was carried out in three sites of Apulia region [Site 1, Alberobello - Murgia foreland; Site 2, Troia (Foggia - Daunian sub-Apennines; Site 3, Monteroni (Lecce - Area of Salento], and in one site of Basilicata region (Site 4, Hill of Matera. The aim was to identify site-specific management practices [by comparing minimum vs conventional tillage, low sowing density vs high sowing density; different levels of nitrogen (N supply and organic fertilisers] in the four different marginal areas, to achieve optimum yield performance for biodiesel prospective production. The crop showed a good adaptability in the study sites, and the highest N level positively influenced the yield performance in Sites 1, 2 and 3. Moreover, the reduction of mechanical operations (minimum tillage did not negatively influence crop production and seed oil content. The highest density of sowing tested determined the best crop performance in Site 3, particularly showing the maximum seed oil content with the lowest N supply. Finally, in Site 4 the compost mixed with mineral N fertiliser as well as the sewage sludge from urban wastewater determined productive results comparable to those obtained with mineral fertiliser, evidencing that organic fertilisers could (partially or completely substitute the mineral one for this crop in the study site. On the whole, seed yield and oil content showed a potential for biodiesel production of Brassica carinata cultivated with site-specific agronomic techniques in four different marginal areas of Southern Italy, suggesting it can be likely achieved the crop environmental adaptation.

  19. Long-term stability of international standards for thromboplastin stored at -20°C, -70°C, and -150°C.

    Science.gov (United States)

    van den Besselaar, A M H P; Abdoel, C F; Hubbard, A R

    2015-07-01

    Long-term stability is an essential requirement for all international biological standards. The main stocks of the current international standards for thromboplastin, i.e. RBT/05 (rabbit brain thromboplastin) and rTF/09 (recombinant human tissue factor), are stored at -20°C. The aim of the present study is to assess the long-term stability of the international sensitivity index (ISI) for RBT/05 and rTF/09. Part of the main stocks of RBT/05 and rTF/09 were stored at -70°C and -150°C, up to 38months. At various time points samples were taken from the materials stored at -20°C, -70°C, and -150°C. The samples were reconstituted and analysed in the prothrombin time (PT) test using plasma samples derived from healthy subjects and patients treated with vitamin K-antagonists (VKA). The PT's obtained with the standards stored at -20°C were compared to the PT's obtained with the standards stored at -70°C and at -150°C. The PT's were used to calculate relative ISI values by means of orthogonal regression. There were no important differences between the ISI values for the materials stored at -20°C, -70°C, and -150°C. There was no significant trend with storage time. The ISI values for the international standards RBT/05 and rTF/09 appear to be stable at storage temperatures of -20°C, -70°C, and -150°C. Copyright © 2015 Elsevier Ltd. All rights reserved.

  20. Dark Matter Search Results from the PICO-2L C3F8 Bubble Chamber

    Energy Technology Data Exchange (ETDEWEB)

    Amole, C.; Ardid, M.; Asner, David M.; Baxter, D.; Behnke, E.; Bhattacharjee, P. S.; Borsodi, H.; Bou-Cabo, M.; Brice, S. J.; Broemmelsiek, D.; Clark, K.; Collar, J. I.; Cooper, P. S.; Crisler, M.; Dahl, C. E.; Daley, S.; Das, Madhusmita; Debris, F.; Dhungana, N.; Farine, J.; Felis, I.; Filgas, R.; Fines-Neuschild, M.; Girard, Francoise; Giroux, G.; Hai, M.; Hall, Jeter C.; Harris, O.; Jackson, C. M.; Jin, M.; Krauss, C. B.; Lafreniere, M.; Laurin, M.; Lawson, I.; Levine, I.; Lippincott, W. H.; Mann, E.; Martin, J. P.; Maurya, D.; Mitra, Pitam; Neilson, R.; Noble, A. J.; Plante, A.; Podviianiuk, R. B.; Priya, S.; Robinson, A. E.; Ruschman, M.; Scallon, O.; Seth, S.; Sonnenschein, Andrew; Starinski, N.; Stekl, I.; Vazquez-Jauregui, E.; Wells, J.; Wichoski, U.; Zacek, V.; Zhang, J.

    2015-06-12

    New data are reported from the operation of a 2-liter C3F8 bubble chamber in the 2100 meter deep SNOLAB underground laboratory, with a total exposure of 211.5 kg-days at four different recoil energy thresholds ranging from 3.2 keV to 8.1 keV. These data show that C3F8 provides excellent electron recoil and alpha rejection capabilities at very low thresholds, including the rst observation of a dependence of acoustic signal on alpha energy. Twelve single nuclear recoil event candidates were observed during the run. The candidate events exhibit timing characteristics that are not consistent with the hypothesis of a uniform time distribution, and no evidence for a dark matter signal is claimed. These data provide the most sensitive direct detection constraints on WIMP-proton spin-dependent scattering to date, with signicant sensitivity at low WIMP masses for spin-independent WIMP-nucleon scattering.

  1. Density functional theoretical study on the C-F and C-O oxidative addition reaction at an AI center

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Yong Seong [Dept. of Science Education, Kyungnam University, Masan (Korea, Republic of); Cho, Hyun; Hwang, Sungu [Dept. of Nanomechatronics Engineering, Pusan National University, Miryang (Korea, Republic of)

    2017-02-15

    In this study, B3LYP/LACVP** level calculations were chosen because the level of theory was applied successfully to calculations of the thermodynamic and kinetic features of the oxidative addition reactions of alkyl and aryl halides to pincer-type complexes. This study examined the effects of the substituents on the phenyl rings of the Al(I) center. Isopropyl side chains in the phenyl rings attached to N atoms of the pincer ligand were replaced with a methyl (Me) (2) or tertiary butyl ( t Bu) group. The oxidative addition of C[BOND]F and C[BOND]O bonds to an Al (I) center was investigated computationally by DFT calculations. The geometries, thermodynamic, and kinetic features were in good agreement with the experimental data, as in previous studies on the transition metal complexes. The computational results showed that the DFT calculations could provide qualitative insight into the reactivity and thermodynamics of the oxidative addition reactions of C[BOND]F bonds.

  2. Containment of c0 and l1 in 1(E, F)

    Indian Academy of Sciences (India)

    R. Narasimhan (Krishtel eMaging) 1461 1996 Oct 15 13:05:22

    By Grothendiéck–Pietsch Dominated Theorem [1], forT ∈ 1(E,F)there exists a regular probability measure µ defined on BE∗ (with its weak ..... [6] Grothendiéck A, Résume des la théorie métriqe des produits tensorials topologique, Bol. Soc. Mat. Sâo Paolo 8 (1956) 1–79. [7] Ryan A, Complemented copies of c0 in injective ...

  3. Stigmaphyllonpatricianum-firmenichianum (Malpighiaceae), a new species from Loyalty Islands, New Caledonia.

    Science.gov (United States)

    Butaud, Jean-François

    2015-01-01

    A new species of Stigmaphyllon (Malpighiaceae) is described: Stigmaphyllonpatricianum-firmenichianum Butaud. It is restricted to the coral islands of Ouvéa, Lifou and Maré in the Loyalty Islands Province (New Caledonia) and is most similar to Stigmaphyllondiscolor (Gand.) C.E.Anderson, known from New Caledonia and Solomon Islands. Previously, plants now known as Stigmaphyllonpatricianum-firmenichianum were included in Stigmaphyllontaomense (Baker f.) C.E.Anderson, endemic to the northern part of Grande-Terre and Belep Islands (New Caledonia). A new circumscription of Stigmaphyllontaomense is proposed. The regional key for New Caledonian species of Stigmaphyllon is updated.

  4. Fabrication and properties of hybrid SiC{sub p}-C{sub f}/Al composite for tribological applications

    Energy Technology Data Exchange (ETDEWEB)

    Imielinska, K. [Gdansk University of Technology, Narutowicza 11/12, 80-952 Gdansk (Poland); Le Petitcorps, Y. [ICMCB-CNRS-UPR 9048, Chateau Brivazac, Av. A Schweitzer, 33608 Pessac (France)

    2005-06-01

    In the present work fabrication of the new hybrid SiC{sub p}/C{sub f}/Al-Si composite, candidate for tribological applications (e.g. brake discs), has been proposed. The composite was obtained by pressure infiltration of continuous 3D carbon fibre preform with SiC{sub p}/Al-Si particulate composite. The presence of carbon preform acted as a filter for liquid SiC{sub p}/Al-Si composite and permitted the formation of surface layer rich in SiC (up to 50%) which resulted in the reduction of weight loss in dry sliding over steel as well as in minimizing the smearing effect of aluminum on the counterface surface which resulted in the reduction of heating on the sliding surface. Due to the presence of continuous carbon fibres the thermal expansion coefficient of hybrid composite has been reduced by a factor of two as compared with that of SiC/Al-Si composite. (Abstract Copyright [2005], Wiley Periodicals, Inc.)

  5. Dark Matter Limits From a 2L C3F8 Filled Bubble Chamber

    Energy Technology Data Exchange (ETDEWEB)

    Robinson, Alan Edward [Univ. of Chicago, IL (United States)

    2015-12-01

    The PICO-2L C3F8 bubble chamber search forWeakly Interacting Massive Particle (WIMP) dark matter was operated in the SNOLAB underground laboratory at the same location as the previous CF3I lled COUPP-4kg detector. Neutron calibrations using photoneutron sources in C3F8 and CF3I lled calibration bubble chambers were performed to verify the sensitivity of these target uids to dark matter scattering. This data was combined with similar measurements using a low-energy neutron beam at the University of Montreal and in situ calibrations of the PICO-2L and COUPP-4kg detectors. C3F8 provides much greater sensitivity to WIMP-proton scattering than CF3I in bubble chamber detectors. PICO-2L searched for dark matter recoils with energy thresholds below 10 keV. Radiopurity assays of detector materials were performed and the expected neutron recoil background was evaluated to be 1.6+0:3

  6. Scleral depressed vitreous shaving, 360 laser, and perfluoropropane (C 3 F 8 for retinal detachment

    Directory of Open Access Journals (Sweden)

    Vivek Chaturvedi

    2014-01-01

    Full Text Available Purpose : To review the characteristics and outcomes of patients who underwent pars plana vitrectomy (PPV with scleral depressed vitreous shaving, 360 degree peripheral endolaser, and 14% C3F8 gas for rhegmatogenous retinal detachment (RRD. Materials and Methods : A retrospective review of a consecutive series of patients who underwent primary repair of RRD by PPV with scleral depressed vitreous shaving, 360 degree peripheral endolaser, and 14% perfluoropropane (C 3 F 8 was conducted. Patients with less than 3 months follow-up, previous retinal surgery, and higher than grade B proliferative vitreoretinopathy were excluded. Results : Ninety-one eyes were included in the study. The mean age was 60.1 years. The mean follow-up was 13.7 months. The macula was detached in 63% (58/91 of the eyes. The reattachment rate after one surgical procedure was 95% (86/91 while overall reattachment rate was 100%. There was no statistically significant difference between reattachment rates of superior, nasal/temporal, or inferior RRDs. The mean final best corrected visual acuity (BCVA was 20/40. Of all the patients, 66% of patients with macula-off RRDs had a final BCVA of 20/40 or better. Conclusions: PPV with scleral depressed vitreous shaving, 360 degree peripheral endolaser, and 14% C 3 F 8 leads to successful anatomical reattachment with visual improvement in patients with primary RRD.

  7. Comparison of qualitative and quantitative imaging characteristics of [11C]PiB and [18F]flutemetamol in normal control and Alzheimer's subjects

    Directory of Open Access Journals (Sweden)

    James M. Mountz

    2015-01-01

    Conclusions: [11C]PiB and [18F]flutemetamol have similar retention characteristics across a range of amyloid negative to positive subjects. Both tracers performed similarly when a standardized visual read technique was used to classify scans as amyloid-positive or amyloid-negative and correlated well with SUVR classifications. However, care in visual interpretation of amyloid positive versus amyloid negative regions should be taken, particularly in the case of [18F]flutemetamol when considering cortical vs. white-matter retention.

  8. Neutral kaon mixing beyond the Standard Model with n f = 2 + 1 chiral fermions. Part 2: non perturbative renormalisation of the Δ F = 2 four-quark operators

    Science.gov (United States)

    Boyle, Peter A.; Garron, Nicolas; Hudspith, Renwick J.; Lehner, Christoph; Lytle, Andrew T.

    2017-10-01

    We compute the renormalisation factors ( Z-matrices) of the Δ F = 2 four-quark operators needed for Beyond the Standard Model (BSM) kaon mixing. We work with n f = 2+1 flavours of Domain-Wall fermions whose chiral-flavour properties are essential to maintain a continuum-like mixing pattern. We introduce new RI-SMOM renormalisation schemes, which we argue are better behaved compared to the commonly-used corresponding RI-MOM one. We find that, once converted to \\overline{MS} , the Z-factors computed through these RI-SMOM schemes are in good agreement but differ significantly from the ones computed through the RI-MOM scheme. The RI-SMOM Z-factors presented here have been used to compute the BSM neutral kaon mixing matrix elements in the companion paper [1]. We argue that the renormalisation procedure is responsible for the discrepancies observed by different collaborations, we will investigate and elucidate the origin of these differences throughout this work.

  9. 41 CFR Appendix C to Chapter 301 - Standard Data Elements for Federal Travel [Traveler Identification

    Science.gov (United States)

    2010-07-01

    ... according to method of payment. Signature/Date Fields Claimant Signature Traveler's signature, or digital... signature, or digital representation. The signature signifies the travel claim is approved for payment based... Regulation System TEMPORARY DUTY (TDY) TRAVEL ALLOWANCES Ch. 301, App. C Appendix C to Chapter 301—Standard...

  10. Prevalence of F5 1691G>A, F2 20210G>A, and MTHFR 677C>T polymorphisms in Bosnian women with pregnancy loss

    Directory of Open Access Journals (Sweden)

    Emir Mahmutbegović

    2017-05-01

    Full Text Available The relationship between genetic risk factors of thrombophilia and pregnancy loss (PL is being discussed. The focus has been on F5 1691G>A, F2 20210G>A, and MTHFR 677C>T polymorphisms that may predispose women to microthrombosis during the stages of embryo implantation and placentation. Although, the frequencies of these polymorphisms were reported in different populations, such studies have not yet been performed in Bosnian population. In this study, we determined the prevalence of F5 G>A (rs6025, F2 G>A (rs1799963 and MTHFR C>T (rs1801133 polymorphisms in Bosnian women. A total of 154 women with PL, mean age 33 (±5.4 years, were enrolled in the study. As a control group, 154 mothers [mean age 31.4 (±6.7 years] with at least one live-born child were included. We used real-time polymerase chain reaction (PCR to determine the frequencies of F5 G>A and F2 G>A genotypes, and PCR-restriction fragment length polymorphism (RFLP for analyzing MTHFR C>T genotypes. The frequency of heterozygotes for F5 and F2 was significantly higher in women with venous thrombosis (VT compared to women without VT (p = 0.047 and p = 0.001, respectively. There was no significant difference in the distribution of MTHFR genotypes and alleles between these two groups. In addition, we observed no significant differences in the genotype and allele frequencies between the group with PL and control group, for all investigated polymorphisms. The allele frequencies for 1691A (F5, 20210A (F2, and 677T (MTHFR reported in this study are consistent with the data obtained for other European countries, however, we were not able to confirm the association between the three polymorphisms and PL in Bosnian women.

  11. The Tris(pentafluoroethyl)stannate(II) Anion, [Sn(C2 F5 )3 ]- -Synthesis and Reactivity.

    Science.gov (United States)

    Wiesemann, Markus; Klösener, Johannes; Niemann, Mark; Neumann, Beate; Stammler, Hans-Georg; Hoge, Berthold

    2017-10-17

    Syntheses of salts containing the tris(pentafluoroethyl)stannate(II) ion, [Sn(C2 F5 )3 ]- , were achieved through deprotonation of the corresponding stannane, HSn(C2 F5 )3 , as well as by direct pentafluoroethylation of SnCl2 with LiC2 F5 . The electron-withdrawing substituents have substantial influence on the stability and reactivity of the anion as documented by its treatment with main group halides. Alkyl halides (R-X) underwent nucleophilic substitutions to afford RSn(C2 F5 )3 , whereas Si, Ge, Sn, P halides gave rise to oxidation processes yielding hypervalent [SnX2 (C2 F5 )3 ]- salts (X=Cl, Br, I). Moreover the unsymmetrical distannane, nBu3 SnSn(C2 F5 )3 , was disclosed as an alternative precursor for the Sn(C2 F5 )3 moiety. Although neither the solid state structure nor its spectra in alkane solution reveal unexpected peculiarities, unusual dissociation of the compound in coordinating solvents into [nBu3 Sn(D)n ]+ and [Sn(C2 F5 )3 ]- ions was observed. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  12. Taxonomy of the genus Chamaesyce S.F. Gray (Euphorbiaceae in the Iberian PeninsuIa and the Balearic Islands

    Directory of Open Access Journals (Sweden)

    Benedí, Carles

    1992-12-01

    Full Text Available A taxonomic study is undertaken of the ten taxa (nine of them specific belonging to the genus Chamaesyce S.F. Gray (Euphorbiaceae which are present in the Iberian Peninsula and the Balearic Islands and a dichotomic key is provided. The taxonomic characteristics or each taxon are discussed and the correct name, synonyms, description, chorology and ecology are given. The presence of Chamaesyce humifusa (Willd. Prokh. in the Iberian Peninsula is confirmed and Chamaesyce humistrata (Gray Small is recorded for the first time from Europe.

    Es realitza un estudi taxonòmic dels 10 tàxons (nou específics del gènere Chamaesyce S.F. Gray (Euphorbiaceae presents a la Península Ibèrica i les Illes Balears. Per a cada tàxon es valoren els caràcters d'interès taxonòmic i s'indica el nom correcte. la sinonímia, descripció, corologia i ecologia. Es confirma la presència de Chamaesyce humifusa (Willd. Prokh, a la Península Ibèrica i se cita Chamaesyce humistrata (Gray Small coma novetat per a Europa.

  13. 46 CFR 154.620 - Design temperature below −55 °C (−67 °F) and down to −165 °C (−265 °F).

    Science.gov (United States)

    2010-10-01

    ... LIQUEFIED GASES Design, Construction and Equipment Materials § 154.620 Design temperature below −55 °C (−67... 46 Shipping 5 2010-10-01 2010-10-01 false Design temperature below â55 °C (â67 °F) and down to... design temperature below −55 °C (−67 °F) and down to −165 °C (−265 °F) must: (a) Meet § 54.25-10(b)(2...

  14. Pyrethroid-resistance and presence of two knockdown resistance (kdr mutations, F1534C and a novel mutation T1520I, in Indian Aedes aegypti.

    Directory of Open Access Journals (Sweden)

    Raja Babu S Kushwah

    2015-01-01

    Full Text Available Control of Aedes aegypti, the mosquito vector of dengue, chikungunya and yellow fever, is a challenging task. Pyrethroid insecticides have emerged as a preferred choice for vector control but are threatened by the emergence of resistance. The present study reports a focus of pyrethroid resistance and presence of two kdr mutations--F1534C and a novel mutation T1520I, in Ae. aegypti from Delhi, India.Insecticide susceptibility status of adult-female Ae. aegypti against DDT (4%, deltamethrin (0.05% and permethrin (0.75% was determined using WHO's standard insecticide susceptibility kit, which revealed resistance to DDT, deltamethrin and permethrin with corrected mortalities of 35%, 72% and 76% respectively. Mosquitoes were screened for the presence of kdr mutations including those reported earlier (I1011V/M, V1016G/I, F1534C, D1794Y and S989P, which revealed the presence of F1534C and a novel mutation T1520I. Highly specific PCR-RFLP assays were developed for genotyping of these two mutations. Genotyping using allele specific PCR and new PCR-RFLP assays revealed a high frequency of F1534C (0.41-0.79 and low frequency of novel mutation T1520I (0.13. The latter was observed to be tightly linked with F1534C and possibly serve as a compensatory mutation. A positive association of F1534C mutation with DDT and deltamethrin resistance in Ae. aegypti was established. However, F1534C-kdr did not show significant protection against permethrin.The Aedes aegypti population of Delhi is resistant to DDT, deltamethrin and permethrin. Two kdr mutations, F1534C and a novel mutation T1520I, were identified in this population. This is the first report of kdr mutations being present in the Indian Ae. aegypti population. Highly specific PCR-RFLP assays were developed for discrimination of alleles at both kdr loci. A positive association of F1534C mutation with DDT and deltamethrin resistance was confirmed.

  15. Pyrethroid-resistance and presence of two knockdown resistance (kdr) mutations, F1534C and a novel mutation T1520I, in Indian Aedes aegypti.

    Science.gov (United States)

    Kushwah, Raja Babu S; Dykes, Cherry L; Kapoor, Neera; Adak, Tridibes; Singh, Om P

    2015-01-01

    Control of Aedes aegypti, the mosquito vector of dengue, chikungunya and yellow fever, is a challenging task. Pyrethroid insecticides have emerged as a preferred choice for vector control but are threatened by the emergence of resistance. The present study reports a focus of pyrethroid resistance and presence of two kdr mutations--F1534C and a novel mutation T1520I, in Ae. aegypti from Delhi, India. Insecticide susceptibility status of adult-female Ae. aegypti against DDT (4%), deltamethrin (0.05%) and permethrin (0.75%) was determined using WHO's standard insecticide susceptibility kit, which revealed resistance to DDT, deltamethrin and permethrin with corrected mortalities of 35%, 72% and 76% respectively. Mosquitoes were screened for the presence of kdr mutations including those reported earlier (I1011V/M, V1016G/I, F1534C, D1794Y and S989P), which revealed the presence of F1534C and a novel mutation T1520I. Highly specific PCR-RFLP assays were developed for genotyping of these two mutations. Genotyping using allele specific PCR and new PCR-RFLP assays revealed a high frequency of F1534C (0.41-0.79) and low frequency of novel mutation T1520I (0.13). The latter was observed to be tightly linked with F1534C and possibly serve as a compensatory mutation. A positive association of F1534C mutation with DDT and deltamethrin resistance in Ae. aegypti was established. However, F1534C-kdr did not show significant protection against permethrin. The Aedes aegypti population of Delhi is resistant to DDT, deltamethrin and permethrin. Two kdr mutations, F1534C and a novel mutation T1520I, were identified in this population. This is the first report of kdr mutations being present in the Indian Ae. aegypti population. Highly specific PCR-RFLP assays were developed for discrimination of alleles at both kdr loci. A positive association of F1534C mutation with DDT and deltamethrin resistance was confirmed.

  16. Development of ASTM Standard for SiC-SiC Joint Testing Final Scientific/Technical Report

    Energy Technology Data Exchange (ETDEWEB)

    Jacobsen, George [General Atomics, San Diego, CA (United States); Back, Christina [General Atomics, San Diego, CA (United States)

    2015-10-30

    As the nuclear industry moves to advanced ceramic based materials for cladding and core structural materials for a variety of advanced reactors, new standards and test methods are required for material development and licensing purposes. For example, General Atomics (GA) is actively developing silicon carbide (SiC) based composite cladding (SiC-SiC) for its Energy Multiplier Module (EM2), a high efficiency gas cooled fast reactor. Through DOE funding via the advanced reactor concept program, GA developed a new test method for the nominal joint strength of an endplug sealed to advanced ceramic tubes, Fig. 1-1, at ambient and elevated temperatures called the endplug pushout (EPPO) test. This test utilizes widely available universal mechanical testers coupled with clam shell heaters, and specimen size is relatively small, making it a viable post irradiation test method. The culmination of this effort was a draft of an ASTM test standard that will be submitted for approval to the ASTM C28 ceramic committee. Once the standard has been vetted by the ceramics test community, an industry wide standard methodology to test joined tubular ceramic components will be available for the entire nuclear materials community.

  17. Heat Islands

    Science.gov (United States)

    EPA's Heat Island Effect Site provides information on heat islands, their impacts, mitigation strategies, related research, a directory of heat island reduction initiatives in U.S. communities, and EPA's Heat Island Reduction Program.

  18. Noninvasive Evaluation of Metabolic Tumor Volume in Lewis Lung Carcinoma Tumor-Bearing C57BL/6 Mice with Micro-PET and the Radiotracers 18F-Alfatide and 18F-FDG: A Comparative Analysis.

    Directory of Open Access Journals (Sweden)

    Yu-Chun Wei

    Full Text Available To explore the value of a new simple lyophilized kit for labeling PRGD2 peptide (18F-ALF-NOTA-PRGD2, denoted as 18F-alfatide in the determination of metabolic tumor volume (MTV with micro-PET in lewis lung carcinoma (LLC tumor-bearing C57BL/6 mice verified by pathologic examination and compared with those using 18F-fluorodeoxyglucose (FDG PET.All LLC tumor-bearing C57BL/6 mice underwent two attenuation-corrected whole-body micro-PET scans with the radiotracers 18F-alfatide and 18F-FDG within two days. 18F-alfatide metabolic tumor volume (VRGD and 18F-FDG metabolic tumor volume (VFDG were manually delineated slice by slice on PET images. Pathologic tumor volume (VPath was measured in vitro after the xenografts were removed.A total of 37 mice with NSCLC xenografts were enrolled and 33 of them underwent 18F-alfatide PET, and 35 of them underwent 18F-FDG PET and all underwent pathological examination. The mean ± standard deviation of VPath, VRGD, and VFDG were 0.59±0.32 cm3 (range,0.13~1.64 cm3, 0.61±0.37 cm3 (range,0.15~1.86 cm3, and 1.24±0.53 cm3 (range,0.17~2.20 cm3, respectively. VPath vs. VRGD, VPath vs. VFDG, and VRGD vs. VFDG comparisons were t = -0.145, P = 0.885, t = -6.239, P<0.001, and t = -5.661, P<0.001, respectively. No significant difference was found between VPath and VRGD. VFDG was much larger than VRGD and VPath. VRGD seemed more approximate to the pathologic gross tumor volume. Furthermore, VPath was more strongly correlated with VRGD (R = 0.964,P<0.001 than with VFDG (R = 0.584,P<0.001.18F-alfatide PET provided a better estimation of gross tumor volume than 18F-FDG PET in LLC tumor-bearing C57BL/6 mice.

  19. Microstructures and mechanical properties of 3D 4-directional, C{sub f}/ZrC–SiC composites using ZrC precursor and polycarbosilane

    Energy Technology Data Exchange (ETDEWEB)

    Li, Qinggang, E-mail: liqinggang66@gmail.com [School of Material Science and Engineering, University of Jinan, Jinan 250022 (China); Shandong Provincial Key Laboratory of Preparation and Measurement of Building Materials, Jinan 250022 (China); Dong, Shaoming [Structural Ceramics and Composites Engineering Research Center, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050 (China); Wang, Zhi; Shi, Guopu; Ma, Yan [School of Material Science and Engineering, University of Jinan, Jinan 250022 (China); Zhou, Haijun; Wang, Zhen; He, Ping [Structural Ceramics and Composites Engineering Research Center, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050 (China)

    2013-11-01

    Highlights: • Three-dimensional 4-directional C{sub f}/ZrC–SiC composites fabricated by polymer infiltration and pyrolysis. • The microstructure and mechanical properties of the composites were studied. • High-temperature oxidation resistance and anti-ablation properties were evaluated. • Results show the composites have good mechanical and excellent ablative properties. -- Abstract: Three-dimensional 4-directional C{sub f}/ZrC–SiC composites were successfully fabricated by polymer infiltration and pyrolysis combined with ZrC precursor impregnation. The microstructure and mechanical properties of the composites were studied. The composite with PyC/SiC interphase had a bulk density of 2.14 g/cm{sup 3}, an open porosity of 10%, and a bending stress of 474 MPa, and exhibited a non-brittle failure behavior due to propagation and deflection of cracks, and fracture and pullout of fibers. Their high-temperature oxidation resistance and anti-ablation properties were evaluated using a muffle furnace and plasma wind tunnel test. Results show that the composites have good mechanical and excellent ablative properties.

  20. Change detection studies of Sagar Island, India, using Indian Remote Sensing Satellite 1C linear imaging self-scan sensor III data

    Digital Repository Service at National Institute of Oceanography (India)

    DineshKumar, P.K.; Gopinath, G.; Laluraj, C.M.; Seralathan, P.; Mitra, D.

    Research 23 6 1498–1502 West Palm Beach, Florida November 2007 Change Detection Studies of Sagar Island, India, using Indian Remote Sensing Satellite 1C Linear Imaging Self-Scan Sensor III Data P.K. Dinesh Kumar † , Girish Gopinath ‡ , C.M. Laluraj † , P...-Scan Sensor III data. Journal of Coastal Research, 23(6), 1498–1502. West Palm Beach (Florida), ISSN 0749-0208. The coastal zone of Sagar Island, India, is subjected to various cyclic and random processes that continuously modify the region. The shoreline...

  1. Final Report - Certifying the Performance of Small Wind Turbines

    Energy Technology Data Exchange (ETDEWEB)

    Sherwood, Larry [Small Wind Certification Council, Clifton Park, NY (United States)

    2015-08-28

    The Small Wind Certification Council (SWCC) created a successful accredited certification program for small and medium wind turbines using the funding from this grant. SWCC certifies small turbines (200 square meters of swept area or less) to the American Wind Energy Association (AWEA) Small Wind Turbine Performance and Safety Standard (AWEA Standard 9.1 – 2009). SWCC also certifies medium wind turbines to the International Electrical Commission (IEC) Power Performance Standard (IEC 61400-12-1) and Acoustic Performance Standard (IEC 61400-11).

  2. 11C-choline vs. 18F-FDG PET/CT in assessing bone involvement in patients with multiple myeloma

    Directory of Open Access Journals (Sweden)

    Ambrosini Valentina

    2007-06-01

    Full Text Available Abstract Background Multiple Myeloma (MM is a B cell neoplasm causing lytic or osteopenic bone abnormalities. Whole body skeletal survey (WBSS, Magnetic resonance (MR and 18F-FDG PET/CT are imaging techniques routinely used for the evaluation of bone involvement in MM patients. Aim As MM bone lesions may present low 18F-FDG uptake; the aim of this study was to assess the possible added value and limitations of 11C-Choline to that of 18F-FDG PET/CT in patients affected with MM. Methods Ten patients affected with MM underwent a standard 11C-Choline PET/CT and an 18F-FDG PET/CT within one week. The results of the two scans were compared in terms of number, sites and SUVmax of lesions. Results Four patients (40% had a negative concordant 11C-Choline and 18F-FDG PET/CT scans. Two patients (20% had a positive 11C-Choline and 18F-FDG PET/CT scans that identified the same number and sites of bone lesions. The remaining four patients (40% had a positive 11C-Choline and 18F-FDG PET/CT scan, but the two exams identified different number of lesions. Choline showed a mean SUVmax of 5 while FDG showed a mean SUVmax of 3.8 (P = 0.042. Overall, 11C-Choline PET/CT scans detected 37 bone lesions and 18F-FDG PET/CT scans detected 22 bone lesions but the difference was not significant (P = 0.8. Conclusion According to these preliminary data, 11C-Choline PET/CT appears to be more sensitive than 18F-FDG PET/CT for the detection of bony myelomatous lesions. If these data are confirmed in larger series of patients, 11C-Choline may be considered a more appropriate functional imaging in association with MRI for MM bone staging.

  3. Amyloid imaging in cognitively normal older adults: comparison between {sup 18}F-flutemetamol and {sup 11}C-Pittsburgh compound B

    Energy Technology Data Exchange (ETDEWEB)

    Adamczuk, Katarzyna; Schaeverbeke, Jolien; Neyens, Veerle; Dupont, Patrick [KU Leuven, Laboratory for Cognitive Neurology, Leuven (Belgium); Leuven Institute of Neuroscience and Disease, Alzheimer Research Centre KU Leuven, Leuven (Belgium); Nelissen, Natalie [KU Leuven, Laboratory for Cognitive Neurology, Leuven (Belgium); Oxford University, Department of Psychiatry, Oxford (United Kingdom); Vandenbulcke, Mathieu [University Hospitals Leuven, Old Age Psychiatry Department, Leuven (Belgium); Goffin, Karolien [KU Leuven and University Hospitals Leuven, Nuclear Medicine and Molecular Imaging Department, Leuven (Belgium); Lilja, Johan [GE Healthcare, Uppsala (Sweden); Department of Surgical Sciences, Radiology, Uppsala University Hospital, Uppsala University, Uppsala (Sweden); Hilven, Kelly [KU Leuven, Laboratory for Neuroimmunology, Leuven (Belgium); Laere, Koen van [Leuven Institute of Neuroscience and Disease, Alzheimer Research Centre KU Leuven, Leuven (Belgium); KU Leuven and University Hospitals Leuven, Nuclear Medicine and Molecular Imaging Department, Leuven (Belgium); Vandenberghe, Rik [KU Leuven, Laboratory for Cognitive Neurology, Leuven (Belgium); Leuven Institute of Neuroscience and Disease, Alzheimer Research Centre KU Leuven, Leuven (Belgium); University Hospitals Leuven, Neurology Department, Leuven (Belgium)

    2016-01-15

    Preclinical, or asymptomatic, Alzheimer's disease (AD) refers to the presence of positive AD biomarkers in the absence of cognitive deficits. This research concept is being applied to define target populations for clinical drug development. In a prospective community-recruited cohort of cognitively intact older adults, we compared two amyloid imaging markers within subjects: {sup 18}F-flutemetamol and {sup 11}C-Pittsburgh compound B (PIB). In 32 community-recruited cognitively intact older adults aged between 65 and 80 years, we determined the concordance between binary classification based on {sup 18}F-flutemetamol versus {sup 11}C-PIB according to semiquantitative assessment (standardized uptake value ratio in composite cortical volume, SUVR{sub comp}) and, alternatively, according to visual reads. We also determined the correlation between {sup 18}F-flutemetamol and {sup 11}C-PIB SUVR and evaluated how this was affected by the reference region chosen (cerebellar grey matter versus pons) and the use of partial volume correction (PVC) in this population. Binary classification based on semiquantitative assessment was concordant between {sup 18}F-flutemetamol and {sup 11}C-PIB in 94 % of cases. Concordance of blinded binary visual reads between tracers was 84 %. The Spearman correlation between {sup 18}F-flutemetamol and {sup 11}C-PIB SUVR{sub comp} with cerebellar grey matter as reference region was 0.84, with a slope of 0.98. Correlations in neocortical regions were significantly lower with the pons as reference region. PVC improved the correlation in striatum and medial temporal cortex. For the definition of preclinical AD based on {sup 18}F-flutemetamol, concordance with {sup 11}C-PIB was highest using semiquantitative assessment with cerebellar grey matter as reference region. (orig.)

  4. High efficiency turbine blade coatings

    Energy Technology Data Exchange (ETDEWEB)

    Youchison, Dennis L. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Gallis, Michail A. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2014-06-01

    The development of advanced thermal barrier coatings (TBCs) of yttria stabilized zirconia (YSZ) that exhibit lower thermal conductivity through better control of electron beam - physical vapor deposition (EB-PVD) processing is of prime interest to both the aerospace and power industries. This report summarizes the work performed under a two-year Lab-Directed Research and Development (LDRD) project (38664) to produce lower thermal conductivity, graded-layer thermal barrier coatings for turbine blades in an effort to increase the efficiency of high temperature gas turbines. This project was sponsored by the Nuclear Fuel Cycle Investment Area. Therefore, particular importance was given to the processing of the large blades required for industrial gas turbines proposed for use in the Brayton cycle of nuclear plants powered by high temperature gas-cooled reactors (HTGRs). During this modest (~1 full-time equivalent (FTE)) project, the processing technology was developed to create graded TBCs by coupling ion beam-assisted deposition (IBAD) with substrate pivoting in the alumina-YSZ system. The Electron Beam - 1200 kW (EB-1200) PVD system was used to deposit a variety of TBC coatings with micron layered microstructures and reduced thermal conductivity below 1.5 W/m.K. The use of IBAD produced fully stoichiometric coatings at a reduced substrate temperature of 600°C and a reduced oxygen background pressure of 0.1 Pa. IBAD was also used to successfully demonstrate the transitioning of amorphous PVD-deposited alumina to the F061>-phase alumina required as an oxygen diffusion barrier and for good adhesion to the substrate Ni2Al3 bondcoat. This process replaces the time consuming thermally grown oxide formation required before the YSZ deposition. In addition to the process technology, Direct Simulation Monte Carlo plume modeling and spectroscopic characterization of the PVD plumes were performed. The project consisted of five tasks. These included the

  5. Distribution of Attenuation Factor Beneath the Japanese Islands

    Science.gov (United States)

    Fujihara, S.; Hashimoto, M.

    2001-12-01

    In this research, we tried to estimate the distribution of attenuation factor of seismic wave, which is closely related to the above-mentioned inelastic parameters. Here the velocity records of events from the Freesia network and the J-array network were used. The events were selected based on the following criteria: (a) events with JMA magnitudes from 3.8 to 5.0 and hypocentral distance from 20km to 200km, (b) events with JMA magnitudes from 5.1 to 6.8 and hypocentral distance from 200km to 10_?, (c) Depth of all events is greater than 30km with S/N ratio greater than 2. After correcting the instrument response, P-wave spectra were estimated. Following Boatwright (1991), the observed spectra were modeled by the theoretical spectra by assuming the following relation; Aij(f) = Si(f) Pij(f) Cj(f). Brune's model (1970) was assumed for the source model. Aij(f), Si(f), Pij(f), and Cj(f) are defined as observed spectrum, source spectrum, propagation effect, and site effect, respectively. Frequency dependence of attenuation factor was not assumed here. The global standard velocity model (AK135) is used for ray tracing. Ellipticity corrections and station elevation corrections are also done. The block sizes are 50km by 50km laterally and increase vertically. As the results of analysis, the attenuation structure beneath Japanese Islands up to the depth of 180km was reconstructed with relatively good resolution. The low Q distribution is clearly seen in central Hokkaido, western Hokkaido, Tohoku region, Hida region, Izu region, and southern Kyushu. The relatively sharp decrease in Q associated with asthenosphere can be seen below the depth of 70km.

  6. Dipole model analysis of F2cc¯${m{F}}_2^{{m{car c}}} $ derived from the new D* data in DIS at HERA

    Directory of Open Access Journals (Sweden)

    Luszczak Agnieszka

    2012-12-01

    Full Text Available I analyse the new D* deep inelastic scattering data from HERA with the help of dipole models. I calculate F2cc¯${m{F}}_2^{{m{car c}}} $ from the GBW [1] and BGK [2] saturation models. I compare results with the last values determined by H1 at low Q2. I find good agreement with the data.

  7. Assessment of specific antibodies to F protein in serum samples from Chinese hepatitis C patients treated with interferon plus ribavarin.

    Science.gov (United States)

    Gao, De-Yong; Zhang, Xin-Xin; Hou, Gang; Jin, Gen-Di; Deng, Qiang; Kong, Xiao-Fei; Zhang, Dong-Hua; Ling, Yun; Yu, De-Min; Gong, Qi-Ming; Zhan, Qin; Yao, Bi-Lian; Lu, Zhi-Meng

    2008-11-01

    The hepatitis C virus (HCV) alternate reading frame protein or F protein of the HCV 1b genotype is a double-frameshift product of the HCV core protein. In order to assess the presence of antibodies specific for F protein and their clinical relevance in sera from HCV patients, we produced recombinant F protein and core protein of the HCV 1b genotype in Escherichia coli. An enzyme-linked immunosorbent assay was developed using purified recombinant HCV core, F protein, and a 99-residue synthetic F peptide (F99). The seroprevalences of anticore, anti-F protein, and anti-F99 synthetic peptide were 95%, 68%, and 36%, respectively, in 168 HCV patients. The prevalence of anti-F antibodies did not correlate with viral load, genotype, or alanine aminotransferase level. Interferon combination therapy induced a decline in the level of anti-F antibodies in 55 responders (P F recombinant protein antibodies, and 17 (31%) lost their anti-F synthetic peptide antibodies, whereas no decrease was observed for the 17 nonresponders. These changes were significant between responders and nonresponders (P F-protein-negative patients (15/15 [100%]) who achieved a sustained virological response (SVR) was higher than that of the anti-F-positive patients (70%) (P F protein elicits a specific antibody response other than the anticore protein response. Our data also suggest that the presence and level of anti-F antibody responses might be influenced by the treatment (interferon plus ribavirin) and associated with an SVR in Chinese hepatitis C patients.

  8. 46 CFR Appendix F to Subpart C of... - Optional Rider for Additional NVOCC Financial Responsibility for Group Bonds [Optional Rider to...

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 9 2010-10-01 2010-10-01 false Optional Rider for Additional NVOCC Financial Responsibility for Group Bonds F Appendix F to Subpart C of Part 515 Shipping FEDERAL MARITIME COMMISSION... Against Ocean Transportation Intermediaries Pt. 515, Subpt. C, App. F Appendix F to Subpart C of Part 515...

  9. Differences in the metabolism and disposition of inhaled (3H)benzene by F344/N rats and B6C3F1 mice

    Energy Technology Data Exchange (ETDEWEB)

    Sabourin, P.J.; Bechtold, W.E.; Birnbaum, L.S.; Lucier, G.; Henderson, R.F.

    1988-06-15

    Benzene is a potent hematotoxin and has been shown to cause leukemia in man. Chronic toxicity studies indicate that B6C3F1 mice are more susceptible than F334/N rats to benzene toxicity. The purpose of the studies presented in this paper was to determine if there were metabolic differences between F344/N rats and B6C3F1 mice which might be responsible for this increased susceptibility. Metabolites of benzene in blood, liver, lung, and bone marrow were measured during and following a 6-hr 50 ppm exposure to benzene vapor. Hydroquinone glucuronide, hydroquinone, and muconic acid, which reflect pathways leading to potential toxic metabolites of benzene, were present in much greater concentrations in the mouse than in rat tissues. Phenylsulfate, a detoxified metabolite, and an unknown water-soluble metabolite were present in approximately equal concentrations in these two species. These results indicate that the proportion of benzene metabolized via pathways leading to the formation of potentially toxic metabolites as opposed to detoxification pathways was much higher in B6C3F1 mice than in F344 rats, which may explain the higher susceptibility of mice to benzene-induced hematotoxicity and carcinogenicity.

  10. Taegu AB, Korea. Revised Uniform Summary of Surface Weather Observations (RUSSWO). Parts A, C-F.

    Science.gov (United States)

    1981-10-07

    c.: if -&ac2 c.a .saia:.s are :;tt;, arCO ira..:a.ry2. S-c~U t.S u rcocriL.: L, it.U Lpr 4 r : .:cc.. : r :’trat u. :-a .fr... ..i.Iar r rar.i...S Del 141b 4 72 00 17734 24.1 7.8311 778s 4 Wei Bulb 397111 160511 Zz 7*48 72_$ D*, Pon .51b 1 71 1 021 0 0 * GL:3AL CLIMATOLOGY BRANCH L’AFLTAC...leet _) Pie . MOb.. mea N.. Mw. witt Tmpopetv RoN.M. 2318961 38509 56.115.15 l 686 s0I s32P .67P 7IT I 0 It1 93 F Total V D.RIb 4287494 5409 78. 67479

  11. Imaging of amyloid deposition in human brain using positron emission tomography and [{sup 18}F]FACT: comparison with [{sup 11}C]PIB

    Energy Technology Data Exchange (ETDEWEB)

    Ito, Hiroshi [National Institute of Radiological Sciences, Molecular Imaging Center, Chiba (Japan); National Institute of Radiological Sciences, Biophysics Program, Molecular Imaging Center, Chiba (Japan); Shinotoh, Hitoshi; Shimada, Hitoshi; Miyoshi, Michie; Takano, Harumasa; Takahashi, Hidehiko; Arakawa, Ryosuke; Kodaka, Fumitoshi; Ono, Maiko; Eguchi, Yoko; Higuchi, Makoto; Fukumura, Toshimitsu; Suhara, Tetsuya [National Institute of Radiological Sciences, Molecular Imaging Center, Chiba (Japan); Yanai, Kazuhiko; Okamura, Nobuyuki [Tohoku University School of Medicine, Department of Pharmacology, Sendai (Japan)

    2014-04-15

    The characteristic neuropathological changes in Alzheimer's disease (AD) are deposition of amyloid senile plaques and neurofibrillary tangles. The {sup 18}F-labeled amyloid tracer, [{sup 18}F]2-[(2-{(E)-2-[2-(dimethylamino)-1,3-thiazol-5-yl]vinyl}-1, 3-benzoxazol-6-yl)oxy ]-3-fluoropropan-1-ol (FACT), one of the benzoxazole derivatives, was recently developed. In the present study, deposition of amyloid senile plaques was measured by positron emission tomography (PET) with both [ {sup 11}C ]Pittsburgh compound B (PIB) and [ {sup 18}F ]FACT in the same subjects, and the regional uptakes of both radiotracers were directly compared. Two PET scans, one of each with [ {sup 11}C ]PIB and [ {sup 18}F ]FACT, were performed sequentially on six normal control subjects, two mild cognitive impairment (MCI) patients, and six AD patients. The standardized uptake value ratio of brain regions to the cerebellum was calculated with partial volume correction using magnetic resonance (MR) images to remove the effects of white matter accumulation. No significant differences in the cerebral cortical uptake were observed between normal control subjects and AD patients in [ {sup 18}F ]FACT studies without partial volume correction, while significant differences were observed in [ {sup 11}C ]PIB. After partial volume correction, the cerebral cortical uptake was significantly larger in AD patients than in normal control subjects for [ {sup 18}F ]FACT studies as well as [ {sup 11}C ]PIB. Relatively lower uptakes of [ {sup 11}C ]PIB in distribution were observed in the medial side of the temporal cortex and in the occipital cortex as compared with [ {sup 18}F ]FACT. Relatively higher uptake of [ {sup 11}C ]PIB in distribution was observed in the frontal and parietal cortices. Since [ {sup 18}F ]FACT might bind more preferentially to dense-cored amyloid deposition, regional differences in cerebral cortical uptake between [ {sup 11}C ]PIB and [ {sup 18}F ]FACT might be due to differences

  12. Protocols for C-Brick DNA Standard Assembly Using Cpf1.

    Science.gov (United States)

    Li, Shi-Yuan; Zhao, Guo-Ping; Wang, Jin

    2017-06-15

    CRISPR-associated protein Cpf1 cleaves double-stranded DNA under the guidance of CRISPR RNA (crRNA), generating sticky ends. Because of this characteristic, Cpf1 has been used for the establishment of a DNA assembly standard called C-Brick, which has the advantage of long recognition sites and short scars. On a standard C-Brick vector, there are four Cpf1 recognition sites - the prefix (T1 and T2 sites) and the suffix (T3 and T4 sites) - flanking biological DNA parts. The cleavage of T2 and T3 sites produces complementary sticky ends, which allow for the assembly of DNA parts with T2 and T3 sites. Meanwhile, a short "GGATCC" scar is generated between parts after assembly. As the newly formed plasmid once again contains the four Cpf1 cleavage sites, the method allows for the iterative assembly of DNA parts, which is similar to those of BioBrick and BglBrick standards. A procedure outlining the use of the C-Brick standard to assemble DNA parts is described here. The C-Brick standard can be widely used by scientists, graduate and undergraduate students, and even amateurs.

  13. NODC Standard Format Marine Birds from Coastal Alaska and Puget Sound Data (1975-1980): Marine Bird Sighting, Land Census (F034) (NODC Accession 0014156)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NODC Standard Marine Bird Sighting, Land Census (F034) is one of a group of seven datasets related to Marine Birds from Coastal Alaska and Puget Sound Data (1975...

  14. Wind turbine on line in Hawaii

    Science.gov (United States)

    Maggs, William Ward

    The largest wind machine in the United States started generating electricity in late July in Hawaii. The Mod-5B wind-powered turbine, located on the northern tip of the island of Oahu, is rated at 3.2 megawatts and is expected to generate enough clean electricity to supply the needs of 1300 homes. The machine was developed at the National Aeronautics and Space Administration (NASA) Lewis Research Center in Cleveland, Ohio, and paid for by the Department of Energy.The turbine is based on new technology that allows its 320-ft (˜100-m) rotor to operate at variable speeds to suit changing wind conditions. It is the result of 15 years of federally sponsored research at NASA-Lewis. Conventional turbines operate at a fixed speed. After 6 months of tests, Mod-5B will be taken over and operated by the Hawaiian Electric Company, under a sales agreement with NASA. The turbine was located at the northend of Oahu primarily because of the high incidence of steady trade winds in that part of the Hawaiian chain. Renewable energy sources like the turbine are also desirable in Hawaii because of the high cost of electricity on the islands, which is principally the result of the need to import all diesel fuel and a prohibition on nuclear power plants in the state.

  15. WE-F-BRB-01: The Power of Ontologies and Standardized Terminologies for Capturing Clinical Knowledge

    Energy Technology Data Exchange (ETDEWEB)

    Gabriel, P. [University of Pennsylvania (United States)

    2015-06-15

    Advancements in informatics in radiotherapy are opening up opportunities to improve our ability to assess treatment plans. Models on individualizing patient dose constraints from prior patient data and shape relationships have been extensively researched and are now making their way into commercial products. New developments in knowledge based treatment planning involve understanding the impact of the radiation dosimetry on the patient. Akin to radiobiology models that have driven intensity modulated radiotherapy optimization, toxicity and outcome predictions based on treatment plans and prior patient experiences may be the next step in knowledge based planning. In order to realize these predictions, it is necessary to understand how the clinical information can be captured, structured and organized with ontologies and databases designed for recall. Large databases containing radiation dosimetry and outcomes present the opportunity to evaluate treatment plans against predictions of toxicity and disease response. Such evaluations can be based on dose volume histogram or even the full 3-dimensional dose distribution and its relation to the critical anatomy. This session will provide an understanding of ontologies and standard terminologies used to capture clinical knowledge into structured databases; How data can be organized and accessed to utilize the knowledge in planning; and examples of research and clinical efforts to incorporate that clinical knowledge into planning for improved care for our patients. Learning Objectives: Understand the role of standard terminologies, ontologies and data organization in oncology Understand methods to capture clinical toxicity and outcomes in a clinical setting Understand opportunities to learn from clinical data and its application to treatment planning Todd McNutt receives funding from Philips, Elekta and Toshiba for some of the work presented.

  16. Evaluation of D-18F-FMT, 18F-FDG, L-11C-MET, and 18F-FLT for monitoring the response of tumors to radiotherapy in mice.

    Science.gov (United States)

    Murayama, Chieko; Harada, Norihiro; Kakiuchi, Takeharu; Fukumoto, Dai; Kamijo, Akemi; Kawaguchi, Akira T; Tsukada, Hideo

    2009-02-01

    O-18F-fluoromethyl-D-tyrosine (D-18F-FMT) is a promising novel agent for tumor imaging by PET. The aim of this study was to evaluate the potential of D-18F-FMT and the other conventional ligands used for tumor imaging, namely, 18F-FDG, L-11C-methionine (L-11C-MET), and 3'-deoxy-3'-18F-fluorothymidine (18F-FLT), as a PET ligand for monitoring early responses to radiotherapy in tumor-bearing mice. C3H/HeN mice inoculated with murine squamous cell carcinomas were treated with a single dose of x-ray irradiation at 2, 6, 20, or 60 Gy. Tumor uptake of each ligand was examined 1, 3, and 7 d after the irradiation. Tumor uptake of D-18F-FMT was decreased on day 1 after irradiation at 6, 20, or 60 Gy, and the decrease persisted until day 7. Tumor uptake of 18F-FDG was elevated on days 1 and 3 after irradiation at 2, 6, or 20 Gy, followed by a decrease in uptake on day 7 in mice irradiated at 20 or 60 Gy. Decreased tumor uptake of L-11C-MET was observed only on day 3 after the irradiation. Decreased tumor uptake of 18F-FLT was detected on day 1 after irradiation at 2, 6, 20, or 60 Gy; thereafter, the dose-dependent decrease in uptake was no longer seen. Only for D-18F-FMT were significant positive correlations found between ligand uptake at all the time points examined and tumor volume on day 14 after various doses of irradiation. The findings suggest that D-18F-FMT is a promising PET ligand for early-phase detection and prediction of the effects of radiation therapy.

  17. Evaluation of Prostate Cancer with 11C- and 18F-Choline PET/CT: Diagnosis and Initial Staging.

    Science.gov (United States)

    Nitsch, Sascha; Hakenberg, Oliver W; Heuschkel, Martin; Dräger, Desiree; Hildebrandt, Guido; Krause, Bernd J; Schwarzenböck, Sarah M

    2016-10-01

    Early diagnosis and adequate staging are crucial for the choice of adequate treatment in prostate cancer (PC). Morphologic and functional imaging modalities, such as CT and MRI, have had limited accuracy in the diagnosis and nodal staging of PC. Molecular PET/CT imaging with 11C- or 18F-choline-labeled derivatives is increasingly being used, but its role in the diagnosis and initial staging of PC is controversial because of limitations in sensitivity and specificity for the detection of primary PC. For T staging, functional MRI is superior to 11C- or 18F-choline PET/CT. For N staging, 11C- or 18F-choline PET/CT can provide potentially useful information that may influence treatment planning. For the detection of bone metastases, 11C- or 18F-choline PET/CT has had promising results; however, in terms of cost-effectiveness, the routine use of 11C- or 18F-choline PET/CT is still debatable. 11C- or 18F-choline PET/CT might be used in high-risk PC before radiation treatment planning, potentially affecting this planning (e.g., regarding dose escalation). This review provides an overview of the diagnostic accuracy and limitations of 11C- or 18F-choline PET/CT in the diagnosis and staging of PC. © 2016 by the Society of Nuclear Medicine and Molecular Imaging, Inc.

  18. Calculation of thermodynamic properties and transport coefficients of C5F10O-CO2 thermal plasmas

    Science.gov (United States)

    Li, Xingwen; Guo, Xiaoxue; Murphy, Anthony B.; Zhao, Hu; Wu, Jian; Guo, Ze

    2017-10-01

    The thermodynamic properties and transport coefficients of C5F10O-CO2 gas mixtures, which are being considered as substitutes for SF6 in circuit breaker applications, are calculated for the temperature range from 300 K to 30 000 K and the pressure range from 0.05 MPa to 1.6 MPa. Special attention is paid on investigating the evolution of thermophysical properties of C5F10O-CO2 mixtures with different mixing ratios and with different pressures; both the mixing ratio and pressure significantly affect the properties. This is explained mainly in terms of the changes in the temperatures at which the dissociation and ionization reactions take place. Comparisons of different thermophysical properties of C5F10O-CO2 mixtures with those of SF6 are also carried out. It is found that most of the thermophysical properties of the C5F10O-CO2 mixtures, such as thermal conductivity, viscosity, and electrical conductivity, become closer to those of SF6 as the C5F10O concentration increases. The composition and thermophysical properties of pure C5F10O in the temperature range from 300 K to 2000 K based on the decomposition pathway are also given. The calculation results provide a basis for further study of the insulation and arc-quenching capability of C5F10O-CO2 gas mixtures as substitutes for SF6.

  19. Dark Matter Search Results from the PICO -60 C 3F8 Bubble Chamber

    Science.gov (United States)

    Amole, C.; Ardid, M.; Arnquist, I. J.; Asner, D. M.; Baxter, D.; Behnke, E.; Bhattacharjee, P.; Borsodi, H.; Bou-Cabo, M.; Campion, P.; Cao, G.; Chen, C. J.; Chowdhury, U.; Clark, K.; Collar, J. I.; Cooper, P. S.; Crisler, M.; Crowder, G.; Dahl, C. E.; Das, M.; Fallows, S.; Farine, J.; Felis, I.; Filgas, R.; Girard, F.; Giroux, G.; Hall, J.; Harris, O.; Hoppe, E. W.; Jin, M.; Krauss, C. B.; Laurin, M.; Lawson, I.; Leblanc, A.; Levine, I.; Lippincott, W. H.; Mamedov, F.; Maurya, D.; Mitra, P.; Nania, T.; Neilson, R.; Noble, A. J.; Olson, S.; Ortega, A.; Plante, A.; Podviyanuk, R.; Priya, S.; Robinson, A. E.; Roeder, A.; Rucinski, R.; Scallon, O.; Seth, S.; Sonnenschein, A.; Starinski, N.; Štekl, I.; Tardif, F.; Vázquez-Jáuregui, E.; Wells, J.; Wichoski, U.; Yan, Y.; Zacek, V.; Zhang, J.; PICO Collaboration

    2017-06-01

    New results are reported from the operation of the PICO-60 dark matter detector, a bubble chamber filled with 52 kg of C3 F8 located in the SNOLAB underground laboratory. As in previous PICO bubble chambers, PICO -60 C 3F8 exhibits excellent electron recoil and alpha decay rejection, and the observed multiple-scattering neutron rate indicates a single-scatter neutron background of less than one event per month. A blind analysis of an efficiency-corrected 1167-kg day exposure at a 3.3-keV thermodynamic threshold reveals no single-scattering nuclear recoil candidates, consistent with the predicted background. These results set the most stringent direct-detection constraint to date on the weakly interacting massive particle (WIMP)-proton spin-dependent cross section at 3.4 ×10-41 cm2 for a 30 -GeV c-2 WIMP, more than 1 order of magnitude improvement from previous PICO results.

  20. Dark Matter Search Results from the PICO-60 C_{3}F_{8} Bubble Chamber.

    Science.gov (United States)

    Amole, C; Ardid, M; Arnquist, I J; Asner, D M; Baxter, D; Behnke, E; Bhattacharjee, P; Borsodi, H; Bou-Cabo, M; Campion, P; Cao, G; Chen, C J; Chowdhury, U; Clark, K; Collar, J I; Cooper, P S; Crisler, M; Crowder, G; Dahl, C E; Das, M; Fallows, S; Farine, J; Felis, I; Filgas, R; Girard, F; Giroux, G; Hall, J; Harris, O; Hoppe, E W; Jin, M; Krauss, C B; Laurin, M; Lawson, I; Leblanc, A; Levine, I; Lippincott, W H; Mamedov, F; Maurya, D; Mitra, P; Nania, T; Neilson, R; Noble, A J; Olson, S; Ortega, A; Plante, A; Podviyanuk, R; Priya, S; Robinson, A E; Roeder, A; Rucinski, R; Scallon, O; Seth, S; Sonnenschein, A; Starinski, N; Štekl, I; Tardif, F; Vázquez-Jáuregui, E; Wells, J; Wichoski, U; Yan, Y; Zacek, V; Zhang, J

    2017-06-23

    New results are reported from the operation of the PICO-60 dark matter detector, a bubble chamber filled with 52 kg of C_{3}F_{8} located in the SNOLAB underground laboratory. As in previous PICO bubble chambers, PICO-60 C_{3}F_{8} exhibits excellent electron recoil and alpha decay rejection, and the observed multiple-scattering neutron rate indicates a single-scatter neutron background of less than one event per month. A blind analysis of an efficiency-corrected 1167-kg day exposure at a 3.3-keV thermodynamic threshold reveals no single-scattering nuclear recoil candidates, consistent with the predicted background. These results set the most stringent direct-detection constraint to date on the weakly interacting massive particle (WIMP)-proton spin-dependent cross section at 3.4×10^{-41}  cm^{2} for a 30-GeV c^{-2} WIMP, more than 1 order of magnitude improvement from previous PICO results.

  1. C-CAP Land Cover, United States Virgin Islands, St John, 2007

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set consists of land cover derived from high resolution imagery and was analyzed according to the Coastal Change Analysis Program (C-CAP) protocol to...

  2. C-CAP Land Cover, Commonwealth of the Northern Mariana Islands (CNMI), Rota 1946

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set consists of land derived from scanned black and white aerial photographs and was analyzed according to the Coastal Change Analysis Program (C-CAP)...

  3. San Juan Island National Historical Park Data Landcover Product - NOAA C-CAP Source

    Data.gov (United States)

    National Park Service, Department of the Interior — NPScape CCAP landcover (CCAP_LAC - 1996, 2001 and 2006) and landcover change (CCAP_LCC) products. Landcover change is produced from the 1996-2001 NOAA C-CAP and...

  4. C-CAP Land Cover, Commonwealth of the Northern Mariana Islands (CNMI), Saipan 2005

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set consists of land derived from high resolution imagery and was analyzed according to the Coastal Change Analysis Program (C-CAP) protocol to determine...

  5. C-CAP Land Cover, Commonwealth of the Northern Mariana Islands (CNMI), Farallon de Pajaros, 2004

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set consists of land derived from high resolution imagery and was analyzed according to the Coastal Change Analysis Program (C-CAP) protocol to determine...

  6. Generic turbine design study. Final report

    Energy Technology Data Exchange (ETDEWEB)

    1993-06-01

    The purpose of Task 12, Generic Turbine Design Study was to develop a conceptual design of a combustion turbine system that would perform in a pressurized fluidized bed combustor (PFBC) application. A single inlet/outlet casing design that modifies the W251B12 combustion turbine to provide compressed air to the PFBC and accept clean hot air from the PFBC was developed. Performance calculations show that the net power output expected, at an inlet temperature of 59{degrees}F, is 20,250 kW.

  7. Permeation of 70% isopropyl alcohol through surgical gloves: comparison of the standard methods ASTM F739 and EN 374.

    Science.gov (United States)

    Mäkelä, Erja A; Vainiotalo, Sinikka; Peltonen, Kimmo

    2003-06-01

    Standard test methods ASTM F739 and EN 374 were compared by assessing the permeation of 70% isopropyl alcohol (2-propanol) through seven brands of surgical gloves. The two standards differ in the flow rates of the collection medium and in the chemical permeation rate at which the breakthrough time (BTT) is detected, the EN detection level being 10 times higher than the permeation rate used by ASTM. In a departure from the EN standard method, a 4 h testing time was used instead of 8 h. All of the tested gloves were from the same manufacturer and were made from either natural rubber (NR) (six brands) or chloroprene rubber (CR) (one brand). Two of the NR glove brands were double layered. For the thin NR gloves (0.22, 0.28 and 0.27 mm) the permeation rates were higher throughout the tests with a flow rate of 474 ml/min (EN) of the collection medium (nitrogen) compared with the permeation rates obtained with a flow rate of 52 ml/min (ASTM). These resulted in BTTs of 4.6, 6.5 and 7.6 min (EN) and 4.8, 6.5 and 9.1 min (ASTM), respectively. No statistical difference could be observed between the BTT values obtained with the two standard methods for any of the thin gloves. Thus, although the ASTM standard has a lower criterion for the detection of permeation, it does not necessarily produce shorter BTTs. For the better barriers the methods yielded more equivalent permeation rate curves and thus the EN BTTs were longer than the ASTM BTTs: the EN results were 21, 80, 122 and >240 min compared with the ASTM results of 12, 32, 38 and 103 min for glove thicknesses of 0.37 (NR), 0.22 + 0.22 (double layered NR), 0.31 + 0.29 (double layered NR) and 0.19 mm (CR), respectively.

  8. Design and construction of a rotor for FC 4000 wind turbine

    Energy Technology Data Exchange (ETDEWEB)

    Ghosh, K.

    1991-07-01

    The F.C. wind motor is a 1.5 wind turbine designed for low wind regimes. The cut in speed is rather low at 3 m/s. It is a multipurpose turbine which produces alternate current electric power that can be used for water pumping, grain grinding and battery charging. The wind turbine directly drives a permanent-magnet generator which has 14 poles and reaches an efficiency of 88% at ca. 430 rotations per minute, and thereafter declines gradually. The design of the windmill is described, including the choice of airfoil, the design of the rotor blade and the construction. The rotor produces an intermittent whistling noise possibly caused by the tip of a blade passing a side vane and causing aerodynamic interference - or by a blade passing the tower, giving a wide and turbulent wake behind this region. (AB)

  9. The Effects of a Liquid Sulfate/Chloride Environment on Superalloy Stress Rupture Properties at 1300 °F (704 °C)

    Science.gov (United States)

    Whitlow, G. A.; Beck, C. G.; Viswanathan, R.; Crombie, E. A.

    1984-01-01

    Data from a stress rupture study on several nickel and cobalt base alloys in a corrosive sulfate/chloride melt at 1300 °F (704 °C) indicated that over the stress range 525 to 700 MPa (75 to 100 ksi), the presence of the environment resulted in considerable reductions in rupture life. Preferential intergranular attack was observed, associated with the diffusion of oxygen and sulfur down a grain boundary to form a sulfide spike, with the subsequent initiation of a crack leading to failure. In an attempt to prevent such effects, it has been found that the application of aluminide or aluminum-chromium diffusion coatings to, for example, a Udimet 710 alloy eliminates this effect, such that rupture life in the salt environment is essentially comparable to that for the uncoated Udimet 710 in air. Modification of the alloy composition with respect to boron and carbon contents, as for instance in a Udimet 720 alloy, has a similar effect. Both approaches are being used to insure the life and reliability of turbine components operating in the low temperature corrosion regime.

  10. Turbine main engines

    CERN Document Server

    Main, John B; Herbert, C W; Bennett, A J S

    1965-01-01

    Turbine Main Engines deals with the principle of operation of turbine main engines. Topics covered include practical considerations that affect turbine design and efficiency; steam turbine rotors, blades, nozzles, and diaphragms; lubricating oil systems; and gas turbines for use with nuclear reactors. Gas turbines for naval boost propulsion, merchant ship propulsion, and naval main propulsion are also considered. This book is divided into three parts and begins with an overview of the basic mode of operation of the steam turbine engine and how it converts the pressure energy of the ingoing ste

  11. Display of cell surface sites for fibronectin assembly is modulated by cell adherence to (1)F3 and C-terminal modules of fibronectin.

    Science.gov (United States)

    Xu, Jielin; Bae, Eunnyung; Zhang, Qinghong; Annis, Douglas S; Erickson, Harold P; Mosher, Deane F

    2009-01-01

    Fibronectin-null cells assemble soluble fibronectin shortly after adherence to a substrate coated with intact fibronectin but not when adherent to the cell-binding domain of fibronectin (modules (7)F3-(10)F3). Interactions of adherent cells with regions of adsorbed fibronectin other than modules (7)F3-(10)F3, therefore, are required for early display of the cell surface sites that initiate and direct fibronectin assembly. To identify these regions, coatings of proteolytically derived or recombinant pieces of fibronectin containing modules in addition to (7)F3-(10)F3 were tested for effects on fibronectin assembly by adherent fibronectin-null fibroblasts. Pieces as large as one comprising modules (2)F3-(14)F3, which include the heparin-binding and cell adhesion domains, were not effective in supporting fibronectin assembly. Addition of module (1)F3 or the C-terminal modules to modules (2)F3-(14)F3 resulted in some activity, and addition of both (1)F3 and the C-terminal modules resulted in a construct, (1)F3-C, that best mimicked the activity of a coating of intact fibronectin. Constructs (1)F3-C V0, (1)F3-C V64, and (1)F3-C Delta(V(15)F3(10)F1) were all able to support fibronectin assembly, suggesting that (1)F3 through (11)F1 and/or (12)F1 were important for activity. Coatings in which the active parts of (1)F3-C were present in different proteins were much less active than intact (1)F3-C. These results suggest that (1)F3 acts together with C-terminal modules to induce display of fibronectin assembly sites on adherent cells.

  12. A cDNA encoding a pRB-binding protein with properties of the transcription factor E2F

    DEFF Research Database (Denmark)

    Helin, K; Lees, J A; Vidal, M

    1992-01-01

    The retinoblastoma protein (pRB) plays an important role in the control of cell proliferation, apparently by binding to and regulating cellular transcription factors such as E2F. Here we describe the characterization of a cDNA clone that encodes a protein with properties of E2F. This clone, RBP3......, was identified by the ability of its gene product to interact with pRB. RBP3 bound to pRB both in vitro and in vivo, and this binding was competed by viral proteins known to disrupt pRB-E2F association. RBP3 bound to E2F recognition sequences in a sequence-specific manner. Furthermore, transient expression...... of RBP3 caused a 10-fold transactivation of the adenovirus E2 promoter, and this transactivation was dependent on the E2F recognition sequences. These properties suggest that RBP3 encodes E2F, or an E2F-like protein....

  13. Structure and flexibility of the C-ring in the electromotor of rotary F(0F(1-ATPase of pea chloroplasts.

    Directory of Open Access Journals (Sweden)

    Shai Saroussi

    Full Text Available A ring of 8-15 identical c-subunits is essential for ion-translocation by the rotary electromotor of the ubiquitous F(OF(1-ATPase. Here we present the crystal structure at 3.4Å resolution of the c-ring from chloroplasts of a higher plant (Pisum sativum, determined using a native preparation. The crystal structure was found to resemble that of an (ancestral cyanobacterium. Using elastic network modeling to investigate the ring's eigen-modes, we found five dominant modes of motion that fell into three classes. They revealed the following deformations of the ring: (I ellipsoidal, (II opposite twisting of the luminal circular surface of the ring against the stromal surface, and (III kinking of the hairpin-shaped monomers in the middle, resulting in bending/stretching of the ring. Extension of the elastic network analysis to rings of different c(n-symmetry revealed the same classes of dominant modes as in P. sativum (c(14. We suggest the following functional roles for these classes: The first and third classes of modes affect the interaction of the c-ring with its counterparts in F(O, namely subunits a and bb'. These modes are likely to be involved in ion-translocation and torque generation. The second class of deformation, along with deformations of subunits γ and ε might serve to elastically buffer the torque transmission between F(O and F(1.

  14. Turbine system and adapter

    Energy Technology Data Exchange (ETDEWEB)

    Hogberg, Nicholas Alvin; Garcia-Crespo, Andres Jose

    2017-05-30

    A turbine system and adapter are disclosed. The adapter includes a turbine attachment portion having a first geometry arranged to receive a corresponding geometry of a wheelpost of a turbine rotor, and a bucket attachment portion having a second geometry arranged to receive a corresponding geometry of a root portion of a non-metallic turbine bucket. Another adapter includes a turbine attachment portion arranged to receive a plurality of wheelposts of a turbine rotor, and a bucket attachment portion arranged to receive a plurality of non-metallic turbine buckets having single dovetail configuration root portions. The turbine system includes a turbine rotor wheel configured to receive metal buckets, at least one adapter secured to at least one wheelpost on the turbine rotor wheel, and at least one non-metallic bucket secured to the at least one adapter.

  15. Pärt: Collage sur B-A-C-H für Kammerorschester / Hans-Christian Dadelsen

    Index Scriptorium Estoniae

    Dadelsen, Hans-Christian

    1993-01-01

    Uuest heliplaadist "Pärt: Collage sur B-A-C-H für Kammerorschester, Summa (1991) für Streichorchester, Fratres, Sinfonie Nr. 2, Festina lente, Wenn Bach Bienen gezüchtet hätte, Credo für Klavier, Chor und Orchester. Philharmonia Orchestra and Chorus, Neeme Järvi". Chandos/Koch CD 9134 (WD: 63'02")

  16. Calculations of total electron-impact ionization cross sections for Fluoroketone C5F10O and Fluoronitrile C4F7N using modified Deutsch-Märk formula

    Science.gov (United States)

    Xiong, Jiayu; Li, Xingwen; Wu, Jian; Guo, Xiaoxue; Zhao, Hu

    2017-11-01

    Both fluoroketone C5F10O and fluoronitrile C4F7N are promising substitute gases for SF6. The electron-impact ionization cross sections for these two gases are calculated using the Deutsch-Märk (DM) formula and its modified method. The necessary molecular geometry optimization and electron population were determined by ab initio calculation, which was performed with quantum chemistry code. The level of calculation, including the theoretical method and basis-set, are carefully determined. To eliminate the drawbacks of the DM formula, a modified DM formula is set in this paper. The modified DM formula, of which the weighting factors are changed, has a better agreement with the experimental data on both the peak and shape of the cross-section curves. The results calculated by DM formula and modified DM formula are given as references to fill in gaps in further research into C5F10O and C4F7N.

  17. Measurement of F_2^{c\\bar{c}} and F_2^{b\\bar{b}} at Low Q^2 and x using the H1 Vertex Detector at HERA

    CERN Document Server

    Aktas, A.; Anthonis, T.; Aplin, S.; Asmone, A.; Astvatsatourov, A.; Babaev, A.; Backovic, S.; Bahr, J.; Baghdasaryan, A.; Baranov, P.; Barrelet, E.; Bartel, W.; Baudrand, S.; Baumgartner, S.; Becker, J.; Beckingham, M.; Behnke, O.; Behrendt, O.; Belousov, A.; Berger, Ch.; Berger, N.; Bizot, J.C.; Boenig, M.-O.; Boudry, V.; Bracinik, J.; Brandt, G.; Brisson, V.; Brown, D.P.; Bruncko, D.; Busser, F.W.; Bunyatyan, A.; Buschhorn, G.; Bystritskaya, L.; Campbell, A.J.; Caron, S.; Cassol-Brunner, F.; Cerny, K.; Cerny, V.; Chekelian, V.; Contreras, J.G.; Coughlan, J.A.; Cox, B.E.; Cozzika, G.; Cvach, J.; Dainton, J.B.; Dau, W.D.; Daum, K.; de Boer, Y.; Delcourt, B.; De Roeck, A.; Desch, K.; De Wolf, E.A.; Diaconu, C.; Dodonov, V.; Dubak, A.; Eckerlin, Guenter; Efremenko, V.; Egli, S.; Eichler, R.; Eisele, F.; Ellerbrock, M.; Erdmann, W.; Essenov, S.; Falkewicz, A.; Faulkner, P.J.W.; Favart, L.; Fedotov, A.; Felst, R.; Ferencei, J.; Finke, L.; Fleischer, M.; Fleischmann, P.; Fleming, Y.H.; Flucke, G.; Fomenko, A.; Foresti, I.; Franke, G.; Frisson, T.; Gabathuler, E.; Garutti, E.; Gayler, J.; Gerlich, C.; Ghazaryan, Samvel; Ginzburgskaya, S.; Glazov, A.; Glushkov, I.; Goerlich, L.; Goettlich, M.; Gogitidze, N.; Gorbounov, S.; Goyon, C.; Grab, C.; Greenshaw, T.; Gregori, M.; Grell, B.R.; Grindhammer, Guenter; Gwilliam, C.; Haidt, D.; Hajduk, L.; Hansson, M.; Heinzelmann, G.; Henderson, R.C.W.; Henschel, H.; Henshaw, O.; Herrera, G.; Hildebrandt, M.; Hiller, K.H.; Hoffmann, D.; Horisberger, R.; Hovhannisyan, A.; Hreus, T.; Hussain, S.; Ibbotson, M.; Ismail, M.; Jacquet, M.; Janauschek, L.; Janssen, X.; Jemanov, V.; Jonsson, L.; Johnson, D.P.; Jung, Andreas Werner; Jung, H.; Kapichine, M.; Katzy, J.; Keller, N.; Kenyon, I.R.; Kiesling, Christian M.; Klein, M.; Kleinwort, C.; Klimkovich, T.; Kluge, T.; Knies, G.; Knutsson, A.; Korbel, V.; Kostka, P.; Krastev, K.; Kretzschmar, J.; Kropivnitskaya, A.; Kruger, K.; Kuckens, J.; Landon, M.P.J.; Lange, W.; Lastovicka, T.; Lastovicka-Medin, G.; Laycock, P.; Lebedev, A.; Leibenguth, G.; Lendermann, V.; Levonian, S.; Lindfeld, L.; Lipka, K.; Liptaj, A.; List, B.; Lobodzinska, E.; Loktionova, N.; Lopez-Fernandez, R.; Lubimov, V.; Lucaci-Timoce, A.-I.; Lueders, H.; Luke, D.; Lux, T.; Lytkin, L.; Makankine, A.; Malden, N.; Malinovski, E.; Mangano, S.; Marage, P.; Marshall, R.; Martisikova, M.; Martyn, H.-U.; Maxeld, S.J.; Meer, D.; Mehta, A.; Meier, K.; Meyer, A.B.; Meyer, H.; Meyer, J.; Mikocki, S.; Milcewicz-Mika, I.; Milstead, D.; Mladenov, D.; Mohamed, A.; Moreau, F.; Morozov, A.; Morris, J.V.; Mozer, Matthias Ulrich; Muller, K.; Murin, P.; Nankov, K.; Naroska, B.; Naumann, Th.; Newman, Paul R.; Niebuhr, C.; Nikiforov, A.; Nikitin, D.; Nowak, G.; Nozicka, M.; Oganezov, R.; Olivier, B.; Olsson, J.E.; Osman, S.; Ozerov, D.; Palichik, V.; Panagoulias, I.; Papadopoulou, T.; Pascaud, C.; Patel, G.D.; Peez, M.; Perez, E.; Perez-Astudillo, D.; Perieanu, A.; Petrukhin, A.; Pitzl, D.; Placakyte, R.; Portheault, B.; Povh, B.; Prideaux, P.; Raicevic, N.; Reimer, P.; Rimmer, A.; Risler, C.; Rizvi, E.; Robmann, P.; Roland, B.; Roosen, R.; Rostovtsev, A.; Rurikova, Z.; Rusakov, S.; Salvaire, F.; Sankey, D.P.C.; Sauvan, E.; Schatzel, S.; Schilling, F.-P.; Schmidt, S.; Schmitt, S.; Schmitz, C.; Schoeffel, L.; Schoning, A.; Schultz-Coulon, H.-C.; Sedlak, K.; Sefkow, F.; Shaw-West, R.N.; Sheviakov, I.; Shtarkov, L.N.; Sloan, T.; Smirnov, P.; Soloviev, Y.; South, D.; Spaskov, V.; Specka, Arnd E.; Stella, B.; Stiewe, J.; Strauch, I.; Straumann, U.; Tchoulakov, V.; Thompson, Graham; Thompson, P.D.; Tomasz, F.; Traynor, D.; Truoel, Peter; Tsakov, I.; Tsipolitis, G.; Tsurin, I.; Turnau, J.; Tzamariudaki, E.; Urban, Marcel; Usik, A.; Utkin, D.; Valkar, S.; Valkarova, A.; Vallee, C.; Van Mechelen, P.; Vargas Trevino, A.; Vazdik, Y.; Veelken, C.; Vest, A.; Vinokurova, S.; Volchinski, V.; Vujicic, B.; Wacker, K.; Wagner, J.; Weber, G.; Weber, R.; Wegener, D.; Werner, C.; Werner, N.; Wessels, M.; Wessling, B.; Wigmore, C.; Wissing, Ch.; Wolf, R.; Wunsch, E.; Xella, S.; Yan, W.; Yeganov, V.; Zacek, J.; Zalesak, J.; Zhang, Z.; Zhelezov, A.; Zhokin, A.; Zhu, Y.C.; Zimmermann, J.; Zimmermann, T.; Zohrabyan, H.; Zomer, F.

    2006-01-01

    Measurements are presented of inclusive charm and beauty cross sections in e^+p collisions at HERA for values of photon virtuality 12 \\le Q^2 \\le 60 GeV^2 and of the Bjorken scaling variable 0.0002 \\le x \\le 0.005. The fractions of events containing charm and beauty quarks are determined using a method based on the impact parameter, in the transverse plane, of tracks to the primary vertex, as measured by the H1 vertex detector. Values for the structure functions F_2^{c\\bar{c}} and F_2^{b\\bar{b}} are obtained. This is the first measurement of F_2^{b\\bar{b}} in this kinematic range. The results are found to be compatible with the predictions of perturbative quantum chromodynamics and withprevious measurements of F_2^{c\\bar{c}}.

  18. [Estimation of the prevalence of attention deficit hyperactivity disorder among the standard population on the island of Majorca].

    Science.gov (United States)

    Cardo, E; Servera, M; Llobera, J

    To determine the rate of prevalence of attention-deficit/ hyperactivity disorder (ADHD) in children of school age (6-11 years) in the Island of Mallorca. The epidemiological study was conducted using a community sample extracted by means of multi-stage stratified sampling according to areas (rural, city and touristy) and schooling (public, private and concerted) and consisted in 1,509 children of both sexes. The ADHD Rating Scales-IV (ADHD RS-IV) for home and school setting were used to collect data. The optimal approach to do a diagnostic evaluation, according with the literature, was using a cut-off point of 90 centil. The estimated prevalence of ADHD was 4.57% (CI at 99%: 3.0-5.8%) and we also obtained 1.26% for the hyperactive subtype, 1.06% for the disattentional subtype, and 2.25% for the combined subtype. Contrary to what was expected, prevalence was higher for females but no statistically significant. There were no statistically significant differences between levels, schools or areas. The estimates for prevalence found in this study are consistent with those reported in the literature (between 3-5%). Using the ADHD rating scale which has different cut-off point regarding age, sex and setting and the fact that it was a poblational based study could explain the higher prevalence in the females. We propose a normalization of the scales in our area in other to confirm our findings.

  19. Turbine maintenance and modernization

    Energy Technology Data Exchange (ETDEWEB)

    Unga, E. [Teollisuuden Voima Oy, Olkiluoto (Finland)

    1998-12-31

    The disturbance-free operation of the turbine plant plays an important role in reaching good production results. In the turbine maintenance of the Olkiluoto nuclear power plant the lifetime and efficiency of turbine components and the lifetime costs are taken into account in determining the turbine maintenance and modernization/improvement program. The turbine maintenance program and improvement/modernization measures taken in the plant units are described in this presentation. (orig.)

  20. HIGH EFFICIENCY TURBINE

    OpenAIRE

    VARMA, VIJAYA KRUSHNA

    2012-01-01

    Varma designed ultra modern and high efficiency turbines which can use gas, steam or fuels as feed to produce electricity or mechanical work for wide range of usages and applications in industries or at work sites. Varma turbine engines can be used in all types of vehicles. These turbines can also be used in aircraft, ships, battle tanks, dredgers, mining equipment, earth moving machines etc, Salient features of Varma Turbines. 1. Varma turbines are simple in design, easy to manufac...

  1. In vitro evaluation of antimicrobial and antioxidant activity of Dragon ’s blood tree (Dracaena cinnabari Balf.f. of Socotra Island (Yemen

    Directory of Open Access Journals (Sweden)

    Abu-Taleb Ahmed Yehia

    2013-09-01

    Full Text Available Objective: To evaluate the performance of preliminary phytochemical, antioxidant and antimicrobial activities of Dracaena cinnabari Balf.f. (Agavaceae (D. cinnabari resin, collected from Socotra Island (Yemen. Methods: The powdered stem resin is extracted with different solvents by using Soxhlet apparatus and evaluated for antioxidant and antimicrobial activity against three Gram positive bacteria (Bacillus cereus NCIM 2106, Staphylococcus aureus NCIM 2127, and Micrococcus luteus NCIM 2169, seven Gram negative bacteria (Escherichia coli NCIM 2924, Pseudomonas aeruginosa NCIM 2863, Salmonella typhimurium NCIM 2501, Klebsiella aerogenes NCIM 2281, Proteus morganii NCIM 2860, Escherichia coli dh5α, Escherichia coli CSH and three fungi (Candida albicans MTCC 227, Aspergillus flavus MTCC 873, Aspergillus niger MTCC 1781. Results: The antimicrobial activity data revealed that, the selected microorganisms possess varied sensitivity response to chloroform extract followed by methanol and benzene extract of D. cinnabari stem resin. The samples also possess a potent DPPH, OH and SO radical scavenging activity. In addition, the preliminary phytochemical analysis demonstrated the presence of alkaloids, flavonoids, terpenoids and other organic compounds which could be reason for antimicrobial activities of D. cinnabari resin. Conclusions: The present study is strengthened for the discovery and development of new antioxidant and antimicrobial drugs from D. cinnabari resin which encourage us to continue with pure fractions.

  2. Reproductive Ecology Of The Florida Scrub-Jay (Aphelocoma Coerulescens) On John F. Kennedy Space Center/Merritt Island National Wildlife Refuge: A Long-Term Study

    Science.gov (United States)

    Carter, Geoffry M.; Breininger, David R.; Larson, Vicky L.; Oddy, Donna M.; Smith, Rebecca B.; Stolen, Eric D.

    2005-01-01

    From 1988 to 2002 we studied the breeding ecology of Florida Scrub-Jays (Aphelocoma coerulescens) on John F. Kennedy Space Center/Merritt Island National Wildlife Refuge. We examined phenology, clutch size, hatching failure rates, fledgling production, nest success, predation rates, sources egg and nestling mortality, and the effects of helpers on these measures. Nesting phenology was similar among sites. Mean clutch size at Titan was significantly larger than at HC or T4. Pairs with helpers did not produce larger clutches than pairs without helpers. Fledgling production at T4 was significantly greater than at HC and similar to Titan. Pairs with helpers at HC produced significantly more fledglings than pairs without helpers; helpers did not influence fledgling production at the other sites. Nest success at HC and Titan was low, 19% and 32% respectively. Nest success at T4 was 48% and was significantly greater than at HC. Average predation rates at all sites increased with season progression. Predation rates at all sight rose sharply by early June. The main cause of nest failure at all sites was predation, 93%.

  3. Power Performance Test Report for the SWIFT Wind Turbine

    Energy Technology Data Exchange (ETDEWEB)

    Mendoza, I.; Hur, J.

    2012-12-01

    This report summarizes the results of a power performance test that NREL conducted on the SWIFT wind turbine. This test was conducted in accordance with the International Electrotechnical Commission's (IEC) standard, Wind Turbine Generator Systems Part 12: Power Performance Measurements of Electricity Producing Wind Turbines, IEC 61400-12-1 Ed.1.0, 2005-12. However, because the SWIFT is a small turbine as defined by IEC, NREL also followed Annex H that applies to small wind turbines. In these summary results, wind speed is normalized to sea-level air density.

  4. Power Curves in a Wind Turbine Array: A Numerical Study

    DEFF Research Database (Denmark)

    Meyer Forsting, Alexander Raul

    The impact of measuring a power curve inside a wind turbine array is investigated using computational fluid dynamics. The array consists of five aligned rotors that yaw with the free-stream wind direction. The flow-field in front of a wind turbine array changes with wind direction and hence...... the individual power output of each turbine. By incorporating the current IEC standards on power performance measurements, the bias in the power performance of turbines in an array over an isolated rotor is determined. The power change depends on the position of the turbine in the array and reaches maximally 9...

  5. Design Load Basis for Offshore Wind turbines

    DEFF Research Database (Denmark)

    Natarajan, Anand; Hansen, Morten Hartvig; Wang, Shaofeng

    2016-01-01

    DTU Wind Energy is not designing and manufacturing wind turbines and does therefore not need a Design Load Basis (DLB) that is accepted by a certification body. However, to assess the load consequences of innovative features and devices added to existing offshore turbine concepts or new offshore...... turbine concept developed in our research, it is useful to have a full DLB that follows the current design standard and is representative of a general DLB used by the industry. It will set a standard for the offshore wind turbine design load evaluations performed at DTU Wind Energy, which is aligned...... with the challenges faced by the industry and therefore ensures that our research continues to have a strong foundation in this interaction. Furthermore, the use of a full DLB that follows the current standard can improve and increase the feedback from the research at DTU Wind Energy to the international...

  6. C/NOFS Observations of AC Electric Field Fields Associated with Equatorial Spread-F

    Science.gov (United States)

    Pfaff, R.; Liebrecht, C.

    2009-01-01

    The Vector Electric Field Investigation (VEFI) on the C/NOFS equatorial satellite provides a unique data set in which to acquire detailed knowledge of irregularities associated with the equatorial ionosphere and in particular with spread-F depletions. We present vector AC electric field observations, primarily gathered within the ELF band (1 Hz to 250 Hz) on C/NOFS that address a variety of key questions regarding how plasma irregularities, from meter to kilometer scales, are created and evolve. The data will be used to explore the anisotropy/isotropy of the waves, their wavelength and phase velocity, as well as their spectral distributions. When analyzed in conjunction with the driving DC electric fields and detailed plasma number density measurements, the combined data reveal important information concerning the instability mechanisms themselves. We also present high resolution, vector measurements of intense lower hybrid waves that have been detected on numerous occasions by the VEFI burst memory VLF electric field channels.

  7. Lentes intraoculares fácicas de câmara posterior

    Directory of Open Access Journals (Sweden)

    Mara Barreto Theiss

    Full Text Available Resumo O objetivo deste artigo foi reunir estudos que reportam resultados disponíveis na literatura científica, considerando a previsibilidade, segurança, eficácia, e estabilidade das lentes intraoculares fácicas de câmara posterior. E relatar as complicações documentadas para estas lentes. A revisão criteriosa dos estudos publicados na literatura ate o momento revelam resultado satisfatórios quanto à eficácia, elevada previsibilidade, estabilidade e segurança do implante de lente intraocular de câmara posterior, para correção das miopia, hipermetropia e astigmatismo.

  8. VHMPID RICH prototype using pressurized C4F8O radiator gas and VUV photon detector

    Science.gov (United States)

    Acconcia, T. V.; Agócs, A. G.; Barile, F.; Barnaföldi, G. G.; Bellwied, R.; Bencédi, G.; Bencze, G.; Berényi, D.; Boldizsár, L.; Chattopadhyay, S.; Chinellato, D. D.; Cindolo, F.; Cossyleon, K.; Das, D.; Das, K.; Das-Bose, L.; Dash, A. K.; D`Ambrosio, S.; De Cataldo, G.; De Pasquale, S.; Di Bari, D.; Di Mauro, A.; Futó, E.; Garcia-Solis, E.; Hamar, G.; Harton, A.; Iannone, G.; Jimenez, R. T.; Kim, D. W.; Kim, J. S.; Knospe, A.; Kovács, L.; Lévai, P.; Markert, C.; Martinengo, P.; Molnár, L.; Nappi, E.; Oláh, L.; Paić, G.; Pastore, C.; Patimo, G.; Patino, M. E.; Peskov, V.; Pinsky, L.; Piuz, F.; Pochybová, S.; Sgura, I.; Sinha, T.; Song, J.; Takahashi, J.; Timmins, A.; Van Beelen, J. B.; Varga, D.; Volpe, G.; Weber, M.; Xaplanteris, L.; Yi, J.; Yoo, I.-K.

    2014-12-01

    A small-size prototype of a new Ring Imaging Cherenkov (RICH) detector using for the first time pressurized C4F8O radiator gas and a photon detector consisting of MWPC equipped with a CsI photocathode has been built and tested at the PS accelerator at CERN. It contained all the functional elements of the detector proposed as Very High Momentum Particle Identification (VHMPID) upgrade for the ALICE experiment at LHC to provide charged hadron track-by-track identification in the momentum range starting from 5 potentially up to 25 GeV/c. In the paper the equipment and its elements are described and some characteristic test results are shown.

  9. Standard Practice for Making and Using C-Ring Stress-Corrosion Test Specimens

    CERN Document Server

    American Society for Testing and Materials. Philadelphia

    2007-01-01

    1.1 This practice covers the essential features of the design and machining, and procedures for stressing, exposing, and inspecting C-ring type of stress-corrosion test specimens. An analysis is given of the state and distribution of stress in the C-ring. 1.2 Specific considerations relating to the sampling process and to the selection of appropriate test environments are outside the scope of this practice. 1.3 The values stated in SI units are to be regarded as the standard; The values given in parentheses are for information only. 1.4 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety and health practices and determine the applicability of regulatory limitations prior to use.

  10. Islands, Island Studies, Island Studies Journal

    Directory of Open Access Journals (Sweden)

    Godfrey Baldacchino

    2006-05-01

    Full Text Available Islands are sites of innovative conceptualizations, whether of nature or human enterprise, whether virtual or real. The study of islands on their own terms today enjoys a growing and wide-ranging recognition. This paper celebrates the launch of Island Studies Journal in the context of a long and thrilling tradition of island studies scholarship.

  11. Medtner: Konzert für Klavier und Orchester Nr. 1 c-Moll op. 33 / Volkmar Fischer

    Index Scriptorium Estoniae

    Fischer, Volkmar

    1992-01-01

    Uuest heliplaadist "Medtner: Konzert für Klavier und Orchester Nr. 1 c-Moll op. 33, Sonaten-Ballade für Klavier Fis-Dur op. 27. London Philharmonic Orchestra / Neeme Järvi". Chandos/Koch CD9039 (WD:54'28")

  12. Non-carcinogenicity of capsaicinoids in B6C3F1 mice.

    Science.gov (United States)

    Akagi, A; Sano, N; Uehara, H; Minami, T; Otsuka, H; Izumi, K

    1998-12-01

    The carcinogenicity of a mixture of capsaicinoids (64.5% capsaicin and 32.6% dihydrocapsaicin) was examined in B6C3F1 mice. In a 13-week toxicity study, renal toxicity was observed in 1% capsaicinoid-treated males. Next, groups of 50 mice of each sex were given 0, 0.025, 0.083 or 0.25% capsaicinoids in powdered diet for 79 weeks and killed in week 83. Food intake was reduced in mice of all capsaicinoid-treated groups, especially females, because of the pungency of capsaicinoids, and inhibition of body weight gain was apparent in females. The numbers of tumour-bearing females in the high-dose groups were significantly lower than that in the controls, and the incidences of hepatocellular neoplasms in both sexes were negatively correlated with the dose of capsaicinoids (Cochran-Armitage trend test). Renal cell adenomas developed in one mouse each of 0.025 and 0.25% capsaicinoid-treated males. The incidences of other tumours were similar in the treated and control groups. Thus, the present study indicated that a mixture of capsaicinoids is not carcinogenic in B6C3F1 mice.

  13. Dark Matter Search Results from the PICO-2L C3F8 Bubble Chamber.

    Science.gov (United States)

    Amole, C; Ardid, M; Asner, D M; Baxter, D; Behnke, E; Bhattacharjee, P; Borsodi, H; Bou-Cabo, M; Brice, S J; Broemmelsiek, D; Clark, K; Collar, J I; Cooper, P S; Crisler, M; Dahl, C E; Daley, S; Das, M; Debris, F; Dhungana, N; Farine, J; Felis, I; Filgas, R; Fines-Neuschild, M; Girard, F; Giroux, G; Hai, M; Hall, J; Harris, O; Jackson, C M; Jin, M; Krauss, C B; Lafrenière, M; Laurin, M; Lawson, I; Levine, I; Lippincott, W H; Mann, E; Martin, J P; Maurya, D; Mitra, P; Neilson, R; Noble, A J; Plante, A; Podviianiuk, R B; Priya, S; Robinson, A E; Ruschman, M; Scallon, O; Seth, S; Sonnenschein, A; Starinski, N; Štekl, I; Vázquez-Jáuregui, E; Wells, J; Wichoski, U; Zacek, V; Zhang, J

    2015-06-12

    New data are reported from the operation of a 2 liter C3F8 bubble chamber in the SNOLAB underground laboratory, with a total exposure of 211.5 kg days at four different energy thresholds below 10 keV. These data show that C3F8 provides excellent electron-recoil and alpha rejection capabilities at very low thresholds. The chamber exhibits an electron-recoil sensitivity of 98.2%. These data also include the first observation of a dependence of acoustic signal on alpha energy. Twelve single nuclear recoil event candidates were observed during the run. The candidate events exhibit timing characteristics that are not consistent with the hypothesis of a uniform time distribution, and no evidence for a dark matter signal is claimed. These data provide the most sensitive direct detection constraints on WIMP-proton spin-dependent scattering to date, with significant sensitivity at low WIMP masses for spin-independent WIMP-nucleon scattering.

  14. Vegetation of eastern Unalaska Island, Aleutian Islands, Alaska

    Science.gov (United States)

    Talbot, Stephen S.; Schofield, Wilfred B.; Talbot, Sandra L.; Daniëls, Fred J. A.

    2010-01-01

    Plant communities of Unalaska Island in the eastern Aleutian Islands of western Alaska, and their relationship to environmental variables, were studied using a combined Braun-Blanquet and multivariate approach. Seventy relevés represented the range of structural and compositional variation in the matrix of vegetation and landform zonation. Eleven major community types were distinguished within six physiognomic–ecological groups: I. Dry coastal meadows: Honckenya peploides beach meadow, Leymus mollis dune meadow. II. Mesic meadows: Athyrium filix-femina – Aconitum maximum meadow, Athyrium filix-femina – Calamagrostis nutkaensis meadow, Erigeron peregrinus – Thelypteris quelpaertensis meadow. III. Wet snowbed meadow: Carex nigricans snowbed meadow. IV. Heath: Linnaea borealis – Empetrum nigrum heath, Phyllodoce aleutica heath, Vaccinium uliginosum – Thamnolia vermicularis fellfield. V. Mire: Carex pluriflora – Plantago macrocarpa mire. VI. Deciduous shrub thicket: Salix barclayi – Athyrium filix-femina thicket. These were interpreted as a complex gradient primarily influenced by soil moisture, elevation, and pH. Phytogeographical and syntaxonomical analysis of the plant communities indicated that the dry coastal meadows, most of the heaths, and the mire vegetation belonged, respectively, to the widespread classes Honckenyo–Elymetea, Loiseleurio–Vaccinietea, and Scheuchzerio–Caricetea, characterized by their circumpolar and widespread species. Amphi-Beringian species were likely diagnostic of amphi-Beringian syntaxa, many of these yet to be described.

  15. Comparative response of platelet fV and plasma fV to activated protein C and relevance to a model of acute traumatic coagulopathy.

    Directory of Open Access Journals (Sweden)

    James E Campbell

    Full Text Available BACKGROUND: Acute traumatic coagulopathy (ATC has been linked to an increase in activated protein C (aPC from 40 pM in healthy individuals to 175 pM. aPC exerts its activity primarily through cleavage of active coagulation factor Va (fVa. Platelets reportedly possess fVa which is more resistant to aPC cleavage than plasma fVa; this work examines the hypothesis that normal platelets are sufficient to maintain coagulation in the presence of elevated aPC. METHODS: Coagulation responses of normal plasma, fV deficient plasma (fVdp, and isolated normal platelets in fVdp were conducted: prothrombin (PT tests, turbidimetry, and thromboelastography (TEG, including the dose response of aPC on the samples. RESULTS: PT and turbidimetric assays demonstrate that normal plasma is resistant to aPC at doses much higher than those found in ATC. Additionally, an average physiological number of washed normal platelets (200,000 platelets/mm3 was sufficient to eliminate the anti-coagulant effects of aPC up to 10 nM, nearly two orders of magnitude above the ATC concentration and even the steady-state pharmacological concentration of human recombinant aPC, as measured by TEG. aPC also demonstrated no significant effect on clot lysis in normal plasma samples with or without platelets. CONCLUSIONS: Although platelet fVa shows slightly superior resistance to aPC's effects compared to plasma fVa in static models, neither fVa is sufficiently cleaved in simulations of ATC or pharmacologically-delivered aPC to diminish coagulation parameters. aPC is likely a correlative indicator of ATC or may play a cooperative role with other activity altering products generated in ATC.

  16. Annual Report: Turbines (30 September 2012)

    Energy Technology Data Exchange (ETDEWEB)

    Alvin, Mary Anne [NETL; Richards, George [NETL

    2012-09-30

    The FY12 NETL-RUA Turbine Thermal Management effort supported the Department of Energy (DOE) Hydrogen Turbine Program through conduct of novel, fundamental, basic, and applied research in the areas of aerothermal heat transfer, coatings development, and secondary flow control. This research project utilized the extensive expertise and facilities readily available at NETL and the participating universities. The research approach includes explorative studies based on scaled models and prototype coupon tests conducted under realistic high-temperature, pressurized, turbine operating conditions. This research is expected to render measurable outcomes that will meet DOE advanced turbine development goals of a 3- to 5-point increase in power island efficiency and a 30 percent power increase above the hydrogen-fired combined cycle baseline. In addition, knowledge gained from this project will further advance the aerothermal cooling and TBC technologies in the general turbine community. This project has been structured to address Development and design of aerothermal and materials concepts in FY12-13. Design and manufacturing of these advanced concepts in FY13. Bench-scale/proof-of-concept testing of these concepts in FY13-14 and beyond. The Turbine Thermal Management project consists of four tasks that focus on a critical technology development in the areas of aerothermal and heat transfer, coatings and materials development, design integration and testing, and a secondary flow rotating rig.

  17. cDNA library Table: F1mg [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available F1mg NA F1mg F1 (J150 x J203) midgut fourth instar larval stage D2 mixed pBluescrip...t SK- EcoR1 for 5' Xho1for 3' sequenced from T3 primer (5' -> 3') BY917461-BY918785,BY925786-BY927071 E_ET_F1mg_[number]_F_0,E_ET_F1mg_[number]_R_0 ...

  18. Large magnetic anisotropy predicted for rare-earth-free F e16 -xC oxN2 alloys

    Science.gov (United States)

    Zhao, Xin; Wang, Cai-Zhuang; Yao, Yongxin; Ho, Kai-Ming

    2016-12-01

    Structures and magnetic properties of F e16 -xC oxN2 are studied using adaptive genetic algorithm and first-principles calculations. We show that substituting Fe with Co in F e16N2 with a Co/Fe ratio ≤1 can greatly improve the magnetic anisotropy of the material. The magnetocrystalline anisotropy energy from first-principles calculations reaches 3.18 MJ / m3 (245.6 μeV per metal atom) for F e12C o4N2 , much larger than that of F e16N2 , and is one of the largest among the reported rare-earth-free magnets. From our systematic crystal structure searches, we show that there is a structure transition from tetragonal F e16N2 to cubic C o16N2 in F e16 -xC oxN2 as the Co concentration increases, which can be well explained by electron counting analysis. Different magnetic properties between the Fe-rich (x ≤8 ) and Co-rich (x >8 ) F e16 -xC oxN2 is closely related to the structural transition.

  19. Standardizing nursing information in Canada for inclusion in electronic health records: C-HOBIC.

    Science.gov (United States)

    Hannah, Kathryn J; White, Peggy A; Nagle, Lynn M; Pringle, Dorothy M

    2009-01-01

    The Canadian Health Outcomes for Better Information and Care (C-HOBIC) project introduced systematic use of standardized clinical nursing terminology for patient assessments. Implemented so far in three Canadian provinces, C-HOBIC comprises an innovative model for large-scale capture of standardized nursing-sensitive clinical outcomes data within electronic health records (EHRs). To support this activity, nursing assessment and outcomes concepts were mapped to the International Classification for Nursing Practice (ICNP(R)). By comparing serial data on a patient across multiple time points, the C-HOBIC model can generate nursing-sensitive patient outcome reports. A principle benefit of the C-HOBIC model is that it provides nurses with information critical to planning for and evaluating patient care. Inclusion of nursing information in either provincial databases or EHRs in three Canadian provinces promotes continuity of patient care across sectors of the healthcare systems in those provinces and also facilitates aggregation and analysis by administrators and policy makers. The C-HOBIC model provides standardized, consistent, interoperable clinical information that reflects nursing practice throughout the Canadian healthcare System.

  20. C-Band Airport Surface Communications System Standards Development, Phase I

    Science.gov (United States)

    Hall, Edward; Isaacs, James; Zelkin, Natalie; Henriksen. Steve

    2010-01-01

    This document is being provided as part of ITT's NASA Glenn Research Center Aerospace Communication Systems Technical Support (ACSTS) contract NNC05CA85C, Task 7: "New ATM Requirements--Future Communications, C-Band and L-Band Communications Standard Development." The proposed future C-band (5091- to 5150-MHz) airport surface communication system, referred to as the Aeronautical Mobile Airport Communications System (AeroMACS), is anticipated to increase overall air-to-ground data communications systems capacity by using a new spectrum (i.e., not very high frequency (VHF)). Although some critical services could be supported, AeroMACS will also target noncritical services, such as weather advisory and aeronautical information services as part of an airborne System Wide Information Management (SWIM) program. AeroMACS is to be designed and implemented in a manner that will not disrupt other services operating in the C-band. This report defines the AeroMACS concepts of use, high-level system requirements, and architecture; the performance of supporting system analyses; the development of AeroMACS test and demonstration plans; and the establishment of an operational AeroMACS capability in support of C-band aeronautical data communications standards to be advanced in both international (International Civil Aviation Organization, ICAO) and national (RTCA) forums. This includes the development of system parameter profile recommendations for AeroMACS based on existing Institute of Electrical and Electronics Engineering (IEEE) 802.16e- 2009 standards

  1. Streamer free operation of a 2 mm gap resistive plate chamber with $C_{2}F_{5}H$

    CERN Document Server

    Cerron-Zeballos, E; Hatzifotiadou, D; Lamas-Valverde, J; Williams, M C S; Zichichi, A

    1999-01-01

    It is necessary to operate the resistive plate chamber (RPC) in avalanche mode to obtain high efficiency at elevated particle fluxes. We examine this mode of operation with a 2 mm gap RPC using gas mixtures containing C/sub 2/F/sub 4/H/sub 2/ and C/sub 2/F/sub 5/H. In order to explain the data we propose that the avalanche growth is strongly limited by space charge effects. (10 refs).

  2. Evaluation of uterine cervix cancer hypoxia by PET with {sup 18}F-F.E.T.N.I.M.. Relation with squamous cell carcinoma (S.C.C.) and osteopontin tumoral markers; Evaluation de l'hypoxie du cancer du col uterin par la TEP au {sup 18}F-FETNIM. Relation avec les marqueurs tumoraux SCC et osteopontine

    Energy Technology Data Exchange (ETDEWEB)

    Barre, E.; Schlageter, M.H.; Groheux, D.; Vercellino, L.; Lussato, D.; Thoury, A.; Hennequin, V.; Hindie, E.; Barranger, E.; Moretti, J.L. [CHU Saint-Louis-Lariboisiere, universite Paris-7, IMDCT, 75 - Paris (France)

    2010-07-01

    Purpose: to evaluate the imaging feasibility of hypoxia of cervical squamous cell carcinoma by PET with {sup 18}F-F.E.T.N.I.M. (Iason). to compare the {sup 18}F-F.E.T.N.I.M. uptake to the metabolic uptake in {sup 18}F-F.D.G. and to study their relationship with the squamous cell carcinoma, tumoral marker and osteoponin, circulating tracer of hypoxia. Conclusions: the F.E.T.N.I.M. uptake by the tumor is always of lower level than the {sup 18}F-F.D.G. uptake. By using the ratio Tumor/Muscle, these preliminary results do not enlighten any correlation between the circulating hypoxia tracer and the tumor uptake of {sup 18}F-F.E.T.N.I.M.. (N.C.)

  3. Using DNA Barcoding and Standardized Sampling to Compare Geographic and Habitat Differentiation of Crustaceans: A Hawaiian Islands Example

    OpenAIRE

    M. Julian Caley; Nancy Knowlton; Laetitia Plaisance; Russell Brainard

    2011-01-01

    Recently, the Census of Marine Life has explored methods to assess coral reef diversity by combining standardized sampling (to permit comparison across sites) with molecular techniques (to make rapid counts of species possible). To date, this approach has been applied across geographically broad scales (seven sites spanning the Indian, Pacific and Atlantic Oceans), focusing on similar habitats at all sites (10–12 m forereef). Here we examine crustacean spatial diversity patterns for a single ...

  4. Inverse Kinematics and Model Calibration Optimization of a Five-D.O.F. Robot for Repairing the Surface Profiles of Hydraulic Turbine Blades

    Directory of Open Access Journals (Sweden)

    Jose Mauricio S.T. Motta

    2016-06-01

    Full Text Available This paper presents and discusses the results of an ongoing R&D project aiming to design and build a fully automated prototype of a specialized spherical robotic welding system for repairing hydraulic turbine surfaces eroded by cavitation pitting and/or cracks produced by cyclic loading. The system has an embedded vision sensor built to acquire range images by laser scanning over the blade's surface and produce 3D models to locate the damaged spots to be registered in a 3D coordinate system into the robot controller, enabling the robot to repair the flaws automatically by welding in layers. The paper is focused on the robot kinematic model and describes an iterative algorithm to process the inverse kinematics with only five degrees-of-freedom. The algorithm makes use of data collected from a vision sensor to ensure that the welding gun axis is perpendicular to the blade's surface. Besides this, it proposes a modelling and optimization mathematical routine for more efficient robot calibration, which can be used with any type of robot. This robot calibration optimization scheme finds the optimal error parameter vector based on the condition number of the manipulator transformation composed from the partial derivatives of the error parameters. Experimental results proved both the iterative algorithm to perform the inverse kinematics and the technique to optimize robot calibration to be very efficient.

  5. 36 degree step size of proton-driven c-ring rotation in FoF1-ATP synthase

    OpenAIRE

    Dueser, Monika G.; Zarrabi, Nawid; Cipriano, Daniel J.; Ernst, Stefan; Glick, Gary D.; Dunn, Stanley D.; Boersch, Michael

    2009-01-01

    Synthesis of the biological "energy currency molecule" adenosine triphosphate ATP is accomplished by FoF1-ATP synthase. In the plasma membrane of Escherichia coli, proton-driven rotation of a ring of 10 c subunits in the Fo motor powers catalysis in the F1 motor. While F1 uses 120 degree stepping, Fo models predict a step-by-step rotation of c subunits 36 degree at a time, which is here demonstrated by single-molecule fluorescence resonance energy transfer.

  6. Duração de Macaulay: fórmulas simplificadas de cálculo

    OpenAIRE

    João da Silva Ferreira

    1995-01-01

    Deduz-se uma nova fórmula simplificada para o cálculo da duração de Macaulay. Mostra-se que esta fórmula permite uma compreensão intuitiva de vários teoremas sobre a duração. Finalmente, mostra-se como se podem deduzir com base nos mesmos resultados outras fórmulas simplificadas de cálculo da duração de Macaulay obtidas por outros investigadores.

  7. Next Generation Engineered Materials for Ultra Supercritical Steam Turbines

    Energy Technology Data Exchange (ETDEWEB)

    Douglas Arrell

    2006-05-31

    To reduce the effect of global warming on our climate, the levels of CO{sub 2} emissions should be reduced. One way to do this is to increase the efficiency of electricity production from fossil fuels. This will in turn reduce the amount of CO{sub 2} emissions for a given power output. Using US practice for efficiency calculations, then a move from a typical US plant running at 37% efficiency to a 760 C /38.5 MPa (1400 F/5580 psi) plant running at 48% efficiency would reduce CO2 emissions by 170kg/MW.hr or 25%. This report presents a literature review and roadmap for the materials development required to produce a 760 C (1400 F) / 38.5MPa (5580 psi) steam turbine without use of cooling steam to reduce the material temperature. The report reviews the materials solutions available for operation in components exposed to temperatures in the range of 600 to 760 C, i.e. above the current range of operating conditions for today's turbines. A roadmap of the timescale and approximate cost for carrying out the required development is also included. The nano-structured austenitic alloy CF8C+ was investigated during the program, and the mechanical behavior of this alloy is presented and discussed as an illustration of the potential benefits available from nano-control of the material structure.

  8. Thermal and Environmental Barrier Coatings for Advanced Turbine Engine Applications

    Science.gov (United States)

    Zhu, Dong-Ming; Miller, Robert A.

    2005-01-01

    Ceramic thermal and environmental barrier coatings (T/EBCs) will play a crucial role in advanced gas turbine engine systems because of their ability to significantly increase engine operating temperatures and reduce cooling requirements, thus help achieve engine low emission and high efficiency goals. Advanced T/EBCs are being developed for the low emission SiC/SiC ceramic matrix composite (CMC) combustor applications by extending the CMC liner and vane temperature capability to 1650 C (3000 F) in oxidizing and water vapor containing combustion environments. Low conductivity thermal barrier coatings (TBCs) are also being developed for metallic turbine airfoil and combustor applications, providing the component temperature capability up to 1650 C (3000 F). In this paper, ceramic coating development considerations and requirements for both the ceramic and metallic components will be described for engine high temperature and high-heat-flux applications. The underlying coating failure mechanisms and life prediction approaches will be discussed based on the simulated engine tests and fracture mechanics modeling results.

  9. Noninvasive quantification of cerebral metabolic rate for glucose in rats using (18)F-FDG PET and standard input function.

    Science.gov (United States)

    Hori, Yuki; Ihara, Naoki; Teramoto, Noboru; Kunimi, Masako; Honda, Manabu; Kato, Koichi; Hanakawa, Takashi

    2015-10-01

    Measurement of arterial input function (AIF) for quantitative positron emission tomography (PET) studies is technically challenging. The present study aimed to develop a method based on a standard arterial input function (SIF) to estimate input function without blood sampling. We performed (18)F-fluolodeoxyglucose studies accompanied by continuous blood sampling for measurement of AIF in 11 rats. Standard arterial input function was calculated by averaging AIFs from eight anesthetized rats, after normalization with body mass (BM) and injected dose (ID). Then, the individual input function was estimated using two types of SIF: (1) SIF calibrated by the individual's BM and ID (estimated individual input function, EIF(NS)) and (2) SIF calibrated by a single blood sampling as proposed previously (EIF(1S)). No significant differences in area under the curve (AUC) or cerebral metabolic rate for glucose (CMRGlc) were found across the AIF-, EIF(NS)-, and EIF(1S)-based methods using repeated measures analysis of variance. In the correlation analysis, AUC or CMRGlc derived from EIF(NS) was highly correlated with those derived from AIF and EIF(1S). Preliminary comparison between AIF and EIF(NS) in three awake rats supported an idea that the method might be applicable to behaving animals. The present study suggests that EIF(NS) method might serve as a noninvasive substitute for individual AIF measurement.

  10. Measurement of susceptibility artifacts with histogram-based reference value on magnetic resonance images according to standard ASTM F2119.

    Science.gov (United States)

    Heinrich, Andreas; Teichgräber, Ulf K; Güttler, Felix V

    2015-12-01

    The standard ASTM F2119 describes a test method for measuring the size of a susceptibility artifact based on the example of a passive implant. A pixel in an image is considered to be a part of an image artifact if the intensity is changed by at least 30% in the presence of a test object, compared to a reference image in which the test object is absent (reference value). The aim of this paper is to simplify and accelerate the test method using a histogram-based reference value. Four test objects were scanned parallel and perpendicular to the main magnetic field, and the largest susceptibility artifacts were measured using two methods of reference value determination (reference image-based and histogram-based reference value). The results between both methods were compared using the Mann-Whitney U-test. The difference between both reference values was 42.35 ± 23.66. The difference of artifact size was 0.64 ± 0.69 mm. The artifact sizes of both methods did not show significant differences; the p-value of the Mann-Whitney U-test was between 0.710 and 0.521. A standard-conform method for a rapid, objective, and reproducible evaluation of susceptibility artifacts could be implemented. The result of the histogram-based method does not significantly differ from the ASTM-conform method.

  11. Development of standardized air-blown coal gasifier/gas turbine concepts for future electric power systems. Volume 2, Appendix A: Fixed bed gasifier and sulfur sorbent regeneration subsystem computer model development: Final report

    Energy Technology Data Exchange (ETDEWEB)

    Blough, E.; Russell, W.; Leach, J.W.

    1990-08-01

    Computer models have been developed for evaluating conceptual designs of integrated coal gasification combined cycle power plants. An overall system model was developed for performing thermodynamic cycle analyses, and detailed models were developed for predicting performance characteristics of fixed bed coal gasifiers and hot gas clean up subsystem components. The overall system model performs mass and energy balances and does chemical equilibrium analyses to determine the effects of changes in operating conditions, or to evaluate proposed design changes. An existing plug flow model for fixed bed gasifiers known as the Wen II model was revised and updated. Also, a spread sheet model of zinc ferrite sulfur sorbent regeneration subsystem was developed. Parametric analyses were performed to determine how performance depends on variables in the system design. The work was done to support CRS Sirrine Incorporated in their study of standardized air blown coal gasifier gas turbine concepts.

  12. Creep-fatigue behavior of turbine disc of superalloy GH720Li at 650 °C and probabilistic creep-fatigue modeling

    Energy Technology Data Exchange (ETDEWEB)

    Hu, Dianyin [School of Energy and Power Engineering, Beihang University, Beijing 100191 (China); Collaborative Innovation Center of Advanced Aero-Engine, Beijing 100191 (China); Beijing Key Laboratory of Aero-Engine Structure and Strength, Beijing 100191 (China); Ma, Qihang [School of Energy and Power Engineering, Beihang University, Beijing 100191 (China); Shang, Lihong [Mining and Materials Engineering, McGill University, Montreal, QC H3A 0C5 (Canada); Gao, Ye [School of Energy and Power Engineering, Beihang University, Beijing 100191 (China); Wang, Rongqiao, E-mail: wangrq@buaa.edu.cn [School of Energy and Power Engineering, Beihang University, Beijing 100191 (China); Collaborative Innovation Center of Advanced Aero-Engine, Beijing 100191 (China); Beijing Key Laboratory of Aero-Engine Structure and Strength, Beijing 100191 (China)

    2016-07-18

    Creep-fatigue experiments have been conducted in nickel-based superalloy GH720Li at an elevated temperature of 650 °C with a stress ratio of 0.1, based on which, different dwell times at the maximum loading were applied to investigate the effect of dwell time on the creep-fatigue behaviors. The tested specimens were cut from the rim region of an actual turbine disc in the hoop direction. The grain size and precipitates of the GH720Li superalloy were examined through scanning electronic microscope (SEM) and energy-dispersive X-ray spectroscopy (EDS) analyses. Experimental data shows creep-fatigue lifetime decreases as the dwell time prolongs. Further, different scattering was observed in the creep-fatigue lifetime at different dwell times. Then a probabilistic model based on the applied mechanical work density (AMWD), with a linear heteroscedastic function that evaluates the non-constant deviation in the creep-fatigue lifetime, was formulated to describe the dependence of creep-fatigue lifetime on the dwell time. Finally, the possible microscopic mechanism of the creep-fatigue behavior has been discussed by SEM with EDS on the fracture surfaces.

  13. High-temperature turbine technology program. Turbine subsystem design report: Low-Btu gas

    Energy Technology Data Exchange (ETDEWEB)

    Horner, M.W.

    1980-12-01

    The objective of the US Department of Energy High-Temperature Turbine Technology (DOE-HTTT) program is to bring to technology readiness a high-temperature (2600/sup 0/F to 3000/sup 0/F firing temperature) turbine within a 6- to 10-year duration, Phase II has addressed the performance of component design and technology testing in critical areas to confirm the design concepts identified in the earlier Phase I program. Based on the testing and support studies completed under Phase II, this report describes the updated turbine subsystem design for a coal-derived gas fuel (low-Btu gas) operation at 2600/sup 0/F turbine firing temperature. A commercial IGCC plant configuration would contain four gas turbines. These gas turbines utilize an existing axial flow compressor from the GE product line MS6001 machine. A complete description of the Primary Reference Design-Overall Plant Design Description has been developed and has been documented. Trends in overall plant performance improvement at higher pressure ratio and higher firing temperature are shown. It should be noted that the effect of pressure ratio on efficiency is significally enhanced at higher firing temperatures. It is shown that any improvement in overall plant thermal efficiency reflects about the same level of gain in Cost of Electricity (COE). The IGCC concepts are shown to be competitive in both performance and cost at current and near-term gas turbine firing temperatures of 1985/sup 0/F to 2100/sup 0/F. The savings that can be accumulated over a thirty-year plant life for a water-cooled gas turbine in an IGCC plant as compared to a state-of-the-art coal-fired steam plant are estimated. A total of $500 million over the life of a 1000 MW plant is projected. Also, this IGCC power plant has significant environmental advantages over equivalent coal-fired steam power plants.

  14. Palaeomagnetic intensities from 14C-dated lava flows on the Big Island, Hawaii: 0-21 kyr

    Science.gov (United States)

    Pressling, Nicola; Laj, Carlo; Kissel, Catherie; Champion, Duane E.; Gubbins, David

    2006-01-01

    Thellier–Thellier experiments were carried out on 216 lava samples collected by the USGS on the Big Island. 35 individual flows from the Kilauea, Mauna Loa and Hualalai volcanoes are represented and independent radiocarbon dating of the flows yields absolute ages ranging from 290 to 20,240 yrs old. The palaeomagnetic analysis was carried out at the Laboratoire des Sciences du Climat et de l'Environnement in Gif-sur-Yvette, France, in two custom built, large capacity furnaces that have been specifically designed to minimise oxidation. The temperature steps were adapted to accommodate the characteristic loss of magnetisation at low temperatures seen in the Curie balance results and the use of half-size samples allowed secondary experiments to be carried out where necessary. The strict PICRIT-03 selection criteria were rigorously applied to the data and a high success rate of 53% has been achieved on a sample level. The flow averaged results almost double the existing 14C-dated palaeointensity dataset for this time window and confirm a period of high intensity over the past 4 kyr preceded by a period in which the dipole moment was weaker. However, the values attained in this study are on average higher than previously published data; reliability of these values is discussed.

  15. Oral administration of a Spirulina extract enriched for Braun-type lipoproteins protects mice against influenza A(H1N1) virus infection

    Science.gov (United States)

    Previous studies indicate that Immulina, a commercial extract of Arthrospira (Spirulina) platensis, is a potent activator of innate immune cells and that Braun-type lipoproteins (a principal toll-like receptor (TLR) 2 ligand) are the main active components within this product. In the present study, ...

  16. A vegetation survey of the Cape of Good Hope Nature Reserve. I. The use of association-analysis and Braun-Blanquet methods*

    Directory of Open Access Journals (Sweden)

    H. C. Taylor

    1984-12-01

    Full Text Available The survey aimed to establish broad vegetation units that could be mapped on an extensive scale in the Cape of Good Hope Nature Reserve at the southern tip of the Cape Peninsula. This paper compares the performance of two methods, association-analysis and the Braun-Blanquet method as developed by the Zurich-Montpellier School of Phytosociology. One hundred 50 m2  sample plots, covering the whole Reserve, were placed systematically at grid intersections on the 1:18 000 topographical map. at 1 000-yard (914 m intervals. Species lists, recording merely presence of all species with permanently recognizable aerial parts, were made for each plot. The association-analysis resulted in a classification of 23 final groups of sample plots, of which only five groups showed high floristic and ecological homogeneity. Of the remainder, eight groups contained some anomalous, misplaced plots, and ten represented small, isolated fragments of natural units. The original data were then analysed using Braun-Blanquet methods to provide an independent classification for comparison with the former. The Braun-Blanquet communities were found to be more homogeneous in terms of previously defined habitat groupings and showed floristic relationships consistent with these groupings. It is concluded that, with the type of sampling used, the synthetic phytosociological Braun-Blanquet method provides a more natural classification of plant communities of the Reserve than does the monothetic divisive association-analysis method.

  17. Enhancement of natural killer cell activity in healthy subjects by Immulina®, a Spirulina extract enriched for Braun-type lipoproteins

    DEFF Research Database (Denmark)

    Nielsen, Claus Henrik; Balachandran, Premalatha; Christensen, Ole

    2010-01-01

    Immulina®, a commercial extract of Arthrospira (Spirulina) platensis is a potent activator of THP-1 monocytes and CD4+ T cells IN VITRO and enhances several immunological functions in mice. We further characterized Immulina® by determining that Braun-type lipoproteins are responsible for a major...

  18. BID-F1 and BID-F2 domains of Bartonella henselae effector protein BepF trigger together with BepC the formation of invasome structures.

    Science.gov (United States)

    Truttmann, Matthias C; Guye, Patrick; Dehio, Christoph

    2011-01-01

    The gram-negative, zoonotic pathogen Bartonella henselae (Bhe) translocates seven distinct Bartonella effector proteins (Beps) via the VirB/VirD4 type IV secretion system (T4SS) into human cells, thereby interfering with host cell signaling [1], [2]. In particular, the effector protein BepG alone or the combination of effector proteins BepC and BepF trigger massive F-actin rearrangements that lead to the establishment of invasome structures eventually resulting in the internalization of entire Bhe aggregates [2], [3]. In this report, we investigate the molecular function of the effector protein BepF in the eukaryotic host cell. We show that the N-terminal [E/T]PLYAT tyrosine phosphorylation motifs of BepF get phosphorylated upon translocation but do not contribute to invasome-mediated Bhe uptake. In contrast, we found that two of the three BID domains of BepF are capable to trigger invasome formation together with BepC, while a mutation of the WxxxE motif of the BID-F1 domain inhibited its ability to contribute to the formation of invasome structures. Next, we show that BepF function during invasome formation can be replaced by the over-expression of constitutive-active Rho GTPases Rac1 or Cdc42. Finally we demonstrate that BID-F1 and BID-F2 domains promote the formation of filopodia-like extensions in NIH 3T3 and HeLa cells as well as membrane protrusions in HeLa cells, suggesting a role for BepF in Rac1 and Cdc42 activation during the process of invasome formation.

  19. BID-F1 and BID-F2 domains of Bartonella henselae effector protein BepF trigger together with BepC the formation of invasome structures.

    Directory of Open Access Journals (Sweden)

    Matthias C Truttmann

    Full Text Available The gram-negative, zoonotic pathogen Bartonella henselae (Bhe translocates seven distinct Bartonella effector proteins (Beps via the VirB/VirD4 type IV secretion system (T4SS into human cells, thereby interfering with host cell signaling [1], [2]. In particular, the effector protein BepG alone or the combination of effector proteins BepC and BepF trigger massive F-actin rearrangements that lead to the establishment of invasome structures eventually resulting in the internalization of entire Bhe aggregates [2], [3]. In this report, we investigate the molecular function of the effector protein BepF in the eukaryotic host cell. We show that the N-terminal [E/T]PLYAT tyrosine phosphorylation motifs of BepF get phosphorylated upon translocation but do not contribute to invasome-mediated Bhe uptake. In contrast, we found that two of the three BID domains of BepF are capable to trigger invasome formation together with BepC, while a mutation of the WxxxE motif of the BID-F1 domain inhibited its ability to contribute to the formation of invasome structures. Next, we show that BepF function during invasome formation can be replaced by the over-expression of constitutive-active Rho GTPases Rac1 or Cdc42. Finally we demonstrate that BID-F1 and BID-F2 domains promote the formation of filopodia-like extensions in NIH 3T3 and HeLa cells as well as membrane protrusions in HeLa cells, suggesting a role for BepF in Rac1 and Cdc42 activation during the process of invasome formation.

  20. Regulation of Trib2 by an E2F1-C/EBPα feedback loop in AML cell proliferation.

    LENUS (Irish Health Repository)

    Rishi, Loveena

    2014-04-10

    The loss of regulation of cell proliferation is a key event in leukemic transformation, and the oncogene tribbles (Trib)2 is emerging as a pivotal target of transcription factors in acute leukemias. Deregulation of the transcription factor E2F1, normally repressed by CCAAT enhancer-binding protein α (C\\/EBPα)-p42, occurs in acute myeloid leukemia (AML), resulting in the perturbation of cell cycle and apoptosis, emphasizing its importance in the molecular pathogenesis of AML. Here we show that E2F family members directly regulate Trib2 in leukemic cells and identify a feedback regulatory loop for E2F1, C\\/EBPα, and Trib2 in AML cell proliferation and survival. Further analyses revealed that E2F1-mediated Trib2 expression was repressed by C\\/EBPα-p42, and in normal granulocyte\\/macrophage progenitor cells, we detect C\\/EBPα bound to the Trib2 promoter. Pharmacological inhibition of the cell cycle or Trib2 knockdown resulted in a block in AML cell proliferation. Our work proposes a novel paradigm whereby E2F1 plays a key role in the regulation of Trib2 expression important for AML cell proliferation control. Importantly, we identify the contribution of dysregulated C\\/EBPα and E2F1 to elevated Trib2 expression and leukemic cell survival, which likely contributes to the initiation and maintenance of AML and may have significant implications for normal and malignant hematopoiesis.

  1. Validation of PROBA-V GEOV1 and MODIS C5 & C6 fAPAR Products in a Deciduous Beech Forest Site in Italy

    Directory of Open Access Journals (Sweden)

    Enrica Nestola

    2017-02-01

    Full Text Available The availability of new fAPAR satellite products requires simultaneous efforts in validation to provide users with a better comprehension of product performance and evaluation of uncertainties. This study aimed to validate three fAPAR satellite products, GEOV1, MODIS C5, and MODIS C6, against ground references to determine to what extent the GCOS requirements on accuracy (maximum 10% or 5% can be met in a deciduous beech forest site in a gently and variably sloped mountain site. Three ground reference fAPAR, differing for temporal (continuous or campaign mode and spatial sampling (single points or Elementary Sampling Units—ESUs, were collected using different devices: (1 Apogee (defined as benchmark in this study; (2 PASTIS; and (3 Digital cameras for collecting hemispherical photographs (DHP. A bottom-up approach for the upscaling process was used in the present study. Radiometric values of decametric images (Landsat-8 were extracted over the ESUs and used to develop empirical transfer functions for upscaling the ground measurements. The resulting high-resolution ground-based maps were aggregated to the spatial resolution of the satellite product to be validated considering the equivalent point spread function of the satellite sensors, and a correlation analysis was performed to accomplish the accuracy assessment. PASTIS sensors showed good performance as fAPARPASTIS appropriately followed the seasonal trends depicted by fAPARAPOGEE (benchmark (R2 = 0.84; RMSE = 0.01. Despite small dissimilarities, mainly attributed to different sampling schemes and errors in DHP classification process, the agreement between fAPARPASTIS and fAPARDHP was noticeable considering all the differences between both approaches. The temporal courses of the three satellite products were found to be consistent with both Apogee and PASTIS, except at the end of the summer season when ground data were more affected by senescent leaves, with both MODIS C5 and C6 displaying

  2. Chemical reactivity of C-F bonds attached to graphene with diamines depending on their nature and location.

    Science.gov (United States)

    Li, Baoyin; He, Taijun; Wang, Zaoming; Cheng, Zheng; Liu, Yang; Chen, Teng; Lai, Wenchuan; Wang, Xu; Liu, Xiangyang

    2016-06-29

    The attachment of fluorine to graphene is a facile means to activate the carbon bonds for subsequent covalent bonding to other molecules for the preparation of desired graphene derivatives. Therefore, an insight into the chemical reactivity of fluorinated graphene (FG) is very essential to enable precise control of the composition and structure of the final products. In this study, FG has been treated with various mass amounts of poly(oxypropylene)diamine (PEA) ranging from starvation to saturation to explore the dependence of a substitution reaction of diamines on the nature and location (attached onto the basal planes or along defects or edges) of C-F bonds. X-ray photoelectron spectroscopy directly tracked the atomic percentage of fluorine present and the carbon 1s bonding state, showing that the grafting ratio of diamines gradually increases with increased diamine mass ratio. The varying of the types and orientation of C-F bonds characterized by polarized attenuated total reflectance Fourier transform infrared spectroscopy indicates that "covalent" C-F bonds are more sensitive to the substitution reaction of diamines than ''semi-ionic'' C-F bonds, and the C-F bonds attached onto basal planes more preferably participate in the functionalization reaction of diamines than that of C-F bonded on non-coplanar regions (edges or defects). The one-dimensional expansion along the graphene c-axis shown by wide angle X-ray diffraction provides further evidence on the preferred functionalization reaction of C-F attached on the basal planes, resulting in a change of the average intersheet distance by various magnitudes.

  3. New Horizons in C-F Activation by Main Group Electrophiles

    Energy Technology Data Exchange (ETDEWEB)

    Ozerov, Oleg V. [Texas A & M Univ., College Station, TX (United States). Dept. of Chemistry

    2016-02-13

    This technical report describes progress on the DOE sponsored project "New Horizons in C-F Activation by Main Group Electrophiles" during the period of 09/15/2010 – 08/31/2015. The main goal of this project was to develop improved catalysts for conversion of carbon-fluorine bonds in potentially harmful compounds. The approach involved combining of a highly reactive positively charged main-group compound with a highly unreactive negatively charged species (anions) as a way to access potent catalysts for carbon-fluorine bond activation. This report details progress made in improving synthetic pathways to a variety of new anions with improved properties and analysis of their potential in catalysis.

  4. Measurement of D^(*+-) Meson Production and F_2^c in Deep-Inelastic Scattering at HERA

    CERN Document Server

    Adloff, C.; Andrieu, B.; Anthonis, T.; Arkadov, V.; Astvatsatourov, A.; Babaev, A.; Bahr, J.; Baranov, P.; Barrelet, E.; Bartel, W.; Bate, P.; Beglarian, A.; Behnke, O.; Beier, C.; Belousov, A.; Benisch, T.; Berger, C.; Berndt, T.; Bizot, J.C.; Boudry, V.; Braunschweig, W.; Brisson, V.; Broker, H.B.; Brown, D.P.; Bruckner, W.; Bruncko, D.; Burger, J.; Busser, F.W.; Bunyatyan, A.; Burrage, A.; Buschhorn, G.; Campbell, A.J.; Cao, Jun; Carli, T.; Caron, S.; Clarke, D.; Clerbaux, B.; Collard, C.; Contreras, J.G.; Coppens, Y.R.; Coughlan, J.A.; Cousinou, M.C.; Cox, B.E.; Cozzika, G.; Cvach, J.; Dainton, J.B.; Dau, W.D.; Daum, K.; Davidsson, M.; Delcourt, B.; Delerue, N.; Demirchyan, R.; De Roeck, A.; De Wolf, E.A.; Diaconu, C.; Dingfelder, J.; Dixon, P.; Dodonov, V.; Dowell, J.D.; Droutskoi, A.; Dubak, A.; Duprel, C.; Eckerlin, Guenter; Eckstein, D.; Efremenko, V.; Egli, S.; Eichler, R.; Eisele, F.; Eisenhandler, E.; Ellerbrock, M.; Elsen, E.; Erdmann, M.; Erdmann, W.; Faulkner, P.J.W.; Favart, L.; Fedotov, A.; Felst, R.; Ferencei, J.; Ferron, S.; Fleischer, M.; Fleming, Y.H.; Flugge, G.; Fomenko, A.; Foresti, I.; Formanek, J.; Foster, J.M.; Franke, G.; Gabathuler, E.; Gabathuler, K.; Garvey, J.; Gassner, J.; Gayler, Joerg; Gerhards, R.; Gerlich, C.; Ghazaryan, Samvel; Goerlich, L.; Gogitidze, N.; Goldberg, M.; Goodwin, C.; Grab, C.; Grassler, H.; Greenshaw, T.; Grindhammer, Guenter; Hadig, T.; Haidt, D.; Hajduk, L.; Haynes, W.J.; Heinemann, B.; Heinzelmann, G.; Henderson, R.C.W.; Hengstmann, S.; Henschel, H.; Heremans, R.; Herrera, G.; Herynek, I.; Hildebrandt, M.; Hilgers, M.; Hiller, K.H.; Hladky, J.; Hoting, P.; Hoffmann, D.; Horisberger, R.; Hurling, S.; Ibbotson, M.; Issever, C .; Jacquet, M.; Jaffre, M.; Janauschek, L.; Jansen, D.M.; Janssen, X.; Jemanov, V.; Jonsson, L.; Johnson, D.P.; Jones, M.A.S.; Jung, H.; Kastli, H.K.; Kant, D.; Kapichine, M.; Karlsson, M.; Karschnick, O.; Keil, F.; Keller, N.; Kennedy, J.; Kenyon, I.R.; Kermiche, S.; Kiesling, Christian M.; Kjellberg, P.; Klein, M.; Kleinwort, C.; Kluge, T.; Knies, G.; Koblitz, B.; Kolya, S.D.; Korbel, V.; Kostka, P.; Kotelnikov, S.K.; Koutouev, R.; Koutov, A.; Krehbiel, H.; Kroseberg, J.; Kruger, K.; Kupper, A.; Kuhr, T.; Kurca, T.; Lahmann, R.; Lamb, D.; Landon, M.P.J.; Lange, W.; Lastovicka, T.; Laycock, P.; Lebailly, E.; Lebedev, A.; Leissner, B.; Lemrani, R.; Lendermann, V.; Levonian, S.; Lindstroem, M.; List, B.; Lobodzinska, E.; Lobodzinski, B.; Loginov, A.; Loktionova, N.; Lubimov, V.; Luders, S.; Luke, D.; Lytkin, L.; Mahlke-Kruger, H.; Malden, N.; Malinovski, E.; Malinovski, I.; Maracek, R.; Marage, P.; Marks, J.; Marshall, R.; Martyn, H.U.; Martyniak, J.; Maxfield, S.J.; Meer, D.; Mehta, A.; Meier, K.; Merkel, P.; Meyer, A.B.; Meyer, H.; Meyer, J.; Meyer, P.O.; Mikocki, S.; Milstead, D.; Mkrtchyan, T.; Mohr, R.; Mohrdieck, S.; Mondragon, M.N.; Moreau, F.; Morozov, A.; Morris, J.V.; Muller, K.; Murin, P.; Nagovizin, V.; Naroska, B.; Naumann, J.; Naumann, T.; Nellen, G.; Newman, Paul R.; Nicholls, T.C.; Niebergall, F.; Niebuhr, C.; Nix, O.; Nowak, G.; Olsson, J.E.; Ozerov, D.; Panassik, V.; Pascaud, C.; Patel, G.D.; Peez, M.; Perez, E.; Phillips, J.P.; Pitzl, D.; Poschl, R.; Potachnikova, I.; Povh, B.; Rabbertz, K.; Radel, G.; Rauschenberger, J.; Reimer, P.; Reisert, B.; Reyna, D.; Risler, C.; Rizvi, E.; Robmann, P.; Roosen, R.; Rostovtsev, A.; Rusakov, S.; Rybicki, K.; Sankey, D.P.C.; Scheins, J.; Schilling, F.P.; Schleper, P.; Schmidt, D.; Schmitt, S.; Schneider, M.; Schoeffel, L.; Schoning, A.; Schorner, T.; Schroder, V.; Schultz-Coulon, H.C.; Schwanenberger, C.; Sedlak, K.; Sefkow, F.; Chekelian, V.; Sheviakov, I.; Shtarkov, L.N.; Sirois, Y.; Sloan, T.; Smirnov, P.; Solochenko, V.; Soloviev, Y.; South, D.; Spaskov, V.; Specka, Arnd E.; Spitzer, H.; Stamen, R.; Stella, B.; Stiewe, J.; Straumann, U.; Swart, M.; Tasevsky, M.; Tchernyshov, V.; Chetchelnitski, S.; Thompson, Graham; Thompson, P.D.; Tobien, N.; Traynor, D.; Truoel, Peter; Tsipolitis, G.; Tsurin, I.; Turnau, J.; Turney, J.E.; Tzamariudaki, E.; Udluft, S.; Usik, A.; Valkar, S.; Valkarova, A.; Vallee, C.; Van Mechelen, P.; Vassiliev, S.; Vazdik, Y.; Vichnevski, A.; Wacker, K.; Wallny, R.; Waugh, B.; Weber, G.; Weber, M.; Wegener, D.; Werner, C.; Werner, M.; Werner, N.; White, G.; Wiesand, S.; Wilksen, T.; Winde, M.; Winter, G.G.; Wissing, C.; Wobisch, M.; Wunsch, E.; Wyatt, A.C.; Zacek, J.; Zalesak, J.; Zhang, Z.; Zhokin, A.; Zomer, F.; Zsembery, J.; zur Nedden, M.

    2002-01-01

    The inclusive production of D^{*+-}(2010) mesons in deep-inelastic scattering is studied with the H1 detector at HERA. In the kinematic region 11.5 GeV and |\\eta_(D^*)|<1.5. Single and double differential inclusive D^(*+-) meson cross sections are compared to perturbative QCD calculations in two different evolution schemes. The charm contribution to the proton structure, F_2^c(x,Q^2), is determined by extrapolating the visible charm cross section to the full phase space. This contribution is found to rise from about 10% at Q^2 = 1.5 GeV^2 to more than 25% at Q^2 = 60 GeV^2 corresponding to x values ranging from 5*10^(-5) to 3*10^(-3)$.

  5. The O({alpha}{sup 3}{sub s}n{sub f}T{sup 2}{sub F}C{sub A,F}) contributions to the gluonic massive operator matrix elements

    Energy Technology Data Exchange (ETDEWEB)

    Bluemlein, Johannes; Hasselhuhn, Alexander [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany); Klein, Sebastian [Technische Hochschule Aachen (Germany). Inst. fuer Theoretische Physik E; Schneider, Carsten [Johannes Kepler Univ., Linz (Austria). Research Inst. for Symbolic Computation

    2012-05-15

    The O({alpha}{sub s}{sup 3}n{sub f}T{sub F}{sup 2}C{sub A,F}) terms to the massive gluonic operator matrix elements are calculated for general values of the Mellin variable N. These twist-2 matrix elements occur as transition functions in the variable flavor number scheme at NNLO. The calculation uses sum-representations in generalized hypergeometric series turning into harmonic sums. The analytic continuation to complex values of N is provided.

  6. A DFIG Islanding Detection Scheme Based on Reactive Power Infusion

    Science.gov (United States)

    Wang, M.; Liu, C.; He, G. Q.; Li, G. H.; Feng, K. H.; Sun, W. W.

    2017-07-01

    A lot of research has been done on photovoltaic (the “PV”) power system islanding detection in recent years. As a comparison, much less attention has been paid to islanding in wind turbines. Meanwhile, wind turbines can work in islanding conditions for quite a long period, which can be harmful to equipments and cause safety hazards. This paper presents and examines a double fed introduction generation (the “DFIG”) islanding detection scheme based on feedback of reactive power and frequency and uses a trigger signal of reactive power infusion which can be obtained by dividing the voltage total harmonic distortion (the "THD") by the voltage THD of last cycle to avoid the deterioration of power quality. This DFIG islanding detection scheme uses feedback of reactive power current loop to amplify the frequency differences in islanding and normal conditions. Simulation results show that the DFIG islanding detection scheme is effective.

  7. Operation Design of Wind Turbines in Strong Wind Conditions

    DEFF Research Database (Denmark)

    Shen, Wen Zhong; Montes, Melissa Barroso; Odgaard, Peter Fogh

    2012-01-01

    optimally. In order to reduce the possible increased loading, fatigue due to the wind gusts, control strategies have been considered for both constant sped and variable speed pitch regulated wind turbines. The control study shows that the designed controllers can reduce the standard deviations efficiently......In order to reduce the impact on the electrical grid from the shutdown of MW wind turbines at wind speeds higher than the cut-out wind speed of 25 m/s, we propose in this paper to run the turbines at high wind speeds up to 40 m/s. Two different operation designs are made for both constant speed...... and variable speed pitch regulated wind turbines. The variable speed design is more suitable for wind turbines to run at very high wind speeds which can help the turbine braking system to stop the turbine at the new "cut-out" wind speed. Reference power, rotational speed and pitch angle have been designed...

  8. Neue biosensorische Prinzipien für die Hämoglobin-A1c Bestimmung

    Science.gov (United States)

    Stöllner, Daniela

    2002-06-01

    Hämoglobin-A1c (HbA1c) ist ein Hämoglobin (Hb)-Subtypus, der durch nicht-enzymatische Glykierung des N-terminalen Valinrestes der Hämoglobin-beta-Kette entsteht. Das gemessene Verhältnis von HbA1c zum Gesamt-Hämoglobin (5-20 % bei Diabetikern) repräsentiert den Mittelwert der Blutglucosekonzentration über einen zweimonatigen Zeitraum und stellt zur Beurteilung der diabetischen Stoffwechsellage eine Ergänzung zur Akutkontrolle der Glukosekonzentration dar. Ziel der vorliegenden Arbeit war es, einen amperometrischen Biosensor für die Bestimmung des medizinisch relevanten Parameters HbA1c zu entwickeln. Durch Selektion geeigneter Bioerkennungselemente und deren Immobilisierung unter Erhalt der Bindungsfunktion für die Zielmoleküle Hämoglobin bzw. HbA1c wurden spezifische, hochaffine und regenerationsstabile Sensoroberflächen geschaffen. Für die Entwicklung des HbA1c-Biosensors wurden zwei Konzepte - Enzymsensor und Immunosensor - miteinander verglichen. Die enzymatische Umsetzung von HbA1c erfolgte mit der Fructosylamin Oxidase (FAO) aus Pichia pastoris N 1-1 unter Freisetzung von H2O2, welches sowohl optisch über eine Indikatorreaktion als auch elektrochemisch nach Einschluss der FAO in PVA-SbQ und Fixierung des Immobilisats vor einer H2O2-Elektrode nachgewiesen wurde. Die Kalibration des Enzymsensors mit der HbA1c-Modellsubstanz Fructosyl-Valin ergab Nachweisgrenzen, die ausserhalb des physiologisch relevanten HbA1c-Konzentrationsbereich lagen. Aus der Umsetzung von glykierten Peptiden mit einer nicht HbA1c analogen Aminosäurensequenz, z.B. Fructosyl-Valin-Glycin wurde zudem eine geringe HbA1c-Spezifität abgeleitet. Für den Immunosensor wurden zwei heterogene Immunoassay-Formate unter Verwendung von hochaffinen und spezifischen Antikörpern in Kombination mit Glucose Oxidase (GOD) als Markerenzym zum Nachweis von HbA1c untersucht. Beim indirekt-kompetitiven Immunoassay wurde anstelle des kompletten HbA1c-Moleküls das glykierte Pentapeptid

  9. [Propositions for the standardized expression of HbA 1c results].

    Science.gov (United States)

    Gillery, P; Périer, C; Bordas-Fonfrède, M; Hue, G; Chapelle, J-P; Vexiau, P; Vialettes, B

    2009-01-01

    The 2007 international consensus about the standardization of HbA(1c) determination and expression of results is progressively implemented in most countries. In France, a common working group of the Société française de biologie clinique (SFBC) and the Société francophone de diabétologie (SFD) has expressed the following recommendations. HbA(1c) results are expressed in percentage of total hemoglobin and in mmol HbA(1c)/mol Hb, but are not converted into estimated average glucose. A table indicating the correspondence between HbA(1c) and estimated average glucose may be given with the results, subject to precautions of interpretation at the individual level.

  10. Electrophilic Ln(III) cations protected by C-F → Ln interactions and their coordination chemistry with weak σ- and π-donors.

    Science.gov (United States)

    Yin, Haolin; Lewis, Andrew J; Carroll, Patrick; Schelter, Eric J

    2013-07-15

    A homoleptic cerium(III) amide complex, Ce(NPh(F)2)3 (1-Ce) (Ph(F) = pentafluorophenyl), in an unusual pseudo-trigonal planar geometry featuring six C-F → Ce interactions was prepared. The C-F → Ln interactions in solution were evident by comparison of the (19)F NMR shifts for the paramagnetic 1-Ce with those of the 4f(0) lanthanum(III) analogue. Coordination of weak σ- and π-donors, including ethers and neutral arene molecules, was achieved by the reversible displacement of the weak C-F → Ce interactions. Computational studies on Ce(NPh(F)2)3 and Ce(NPh(F)2)3(η(6)-C6H3Me3) provide information on the F → Ce interactions and Ce-η(6)-arene bonding.

  11. Validation of PROBA-V GEOV1 and MODIS C5 & C6 fAPAR Products in a Deciduous Beech Forest Site in Italy

    Czech Academy of Sciences Publication Activity Database

    Nestola, E.; Sanchez-Zapero, J.; Latorre, C.; Mazzenga, F.; Matteucci, G.; Calfapietra, Carlo; Camacho, F.

    2017-01-01

    Roč. 9, č. 2 (2017), č. článku 126. ISSN 2072-4292 Institutional support: RVO:86652079 Keywords : fAPAR * validation * PROBA-V GEOV1 * MODIS C5 * MODIS C6 * beech forest * up-scaling * GCOS requirements * in-situ comparison and evaluation Subject RIV: EH - Ecology, Behaviour Impact factor: 3.244, year: 2016

  12. Effect of prolonged standardized bed rest on cystatin C and other markers of cardiovascular risk

    Directory of Open Access Journals (Sweden)

    Arinell Karin

    2011-12-01

    Full Text Available Abstract Background Sedentary lifestyle is associated with coronary artery disease but even shorter periods of physical inactivity may increase cardiovascular risk. Cystatin C is independently associated with cardiovascular disease and our objective was to investigate the relation between this novel biomarker and standardized bed rest. Research of immobilization physiology in humans is challenging because good biological models are in short supply. From the Women International Space simulation for Exploration study (WISE we studied markers of atherosclerosis and kidney function, including cystatin C, in a standardized bed rest study on healthy volunteers. Fifteen healthy female volunteers participated in a 20-day ambulatory control period followed by 60 days of bed rest in head-down tilt position (-6° 24 h a day, finalized by 20 days of recovery. The subjects were randomized into two groups during bed rest: a control group (n = 8 that remained physically inactive and an exercise group (n = 7 that participated in both supine resistance and aerobic exercise training. Results Compared to baseline values there was a statistically significant increase in cystatin C in both groups after bed rest (P Conclusion During and following prolonged standardized bed rest the concentrations of several clinically relevant cardiovascular risk markers change.

  13. The k-ε-fP model applied to wind farms

    DEFF Research Database (Denmark)

    Laan, van der, Paul Maarten; Sørensen, Niels N.; Réthoré, Pierre-Elouan

    2015-01-01

    the model results with a Gaussian filter. The standard k-ε eddy-viscosity model underpredicts the power deficit of the first downstream wind turbines, whereas the k-ε-fP eddy-viscosity model shows a good agreement with the measurements. However, the difference in the power deficit predicted...

  14. Experimental and Theoretical Study on the OH-Reaction Kinetics and Photochemistry of Acetyl Fluoride (CH3C(O)F), an Atmospheric Degradation Intermediate of HFC-161 (C2H5F).

    Science.gov (United States)

    Song, Xinli; Zügner, Gábor L; Farkas, Mária; Illés, Ádám; Sarzyński, Dariusz; Rozgonyi, Tamás; Wang, Baoshan; Dóbé, Sándor

    2015-07-16

    The direct reaction kinetic method of low pressure fast discharge flow (DF) with resonance fluorescence monitoring of OH (RF) has been applied to determine rate coefficients for the overall reactions OH + C2H5F (EtF) (1) and OH + CH3C(O)F (AcF) (2). Acetyl fluoride reacts slowly with the hydroxyl radical, the rate coefficient at laboratory temperature is k2(300 K) = (0.74 ± 0.05) × 10(-14) cm(3) molecule(-1) s(-1) (given with 2σ statistical uncertainty). The temperature dependence of the reaction does not obey the Arrhenius law and it is described well by the two-exponential rate expression of k2(300-410 K) = 3.60 × 10(-3) exp(-10500/T) + 1.56 × 10(-13) exp(-910/T) cm(3) molecule(-1) s(-1). The rate coefficient of k1 = (1.90 ± 0.19) × 10(-13) cm(3) molecule(-1) s(-1) has been determined for the EtF-reaction at room temperature (T = 298 K). Microscopic mechanisms for the OH + CH3C(O)F reaction have also been studied theoretically using the ab initio CBS-QB3 and G4 methods. Variational transition state theory was employed to obtain rate coefficients for the OH + CH3C(O)F reaction as a function of temperature on the basis of the ab initio data. The calculated rate coefficients are in good agreement with the experimental data. It is revealed that the reaction takes place predominantly via the indirect H-abstraction mechanism involving H-bonded prereactive complexes and forming the nascent products of H2O and the CH2CFO radical. The non-Arrhenius behavior of the rate coefficient at temperatures below 500 K is ascribed to the significant tunneling effect of the in-the-plane H-abstraction dynamic bottleneck. The production of FC(O)OH + CH3 via the addition/elimination mechanism is hardly competitive due to the significant barriers along the reaction routes. Photochemical experiments of AcF were performed at 248 nm by using exciplex lasers. The total photodissociation quantum yield for CH3C(O)F has been found significantly less than unity; among the primary

  15. Molokai Photomosaic 2000 (328c-0516) - Orthorectification and Mosaicing of Color Aerial Photography for the Main Eight Hawaiian Islands

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Habitat maps of the main Hawaiian Islands were created by visual interpretation of aerial photos and hyperspectral imagery using the Habitat Digitizer extension....

  16. Orthorectification and Mosaicking of Color Aerial Photography for the Main Eight Hawaiian Islands: Kauai (103-104c-0430)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Habitat maps of the main Hawaiian Islands were created by visual interpretation of aerial photos and hyperspectral imagery using the Habitat Digitizer extension....

  17. Kauai Photomosaic 2000 (103-104c-0430) - Orthorectification and Mosaicing of Color Aerial Photography Main Eight Hawaiian Islands

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Habitat maps of the main Hawaiian Islands were created by visual interpretation of aerial photos and hyperspectral imagery using the Habitat Digitizer extension....

  18. Orthorectification and Mosaicking of Color Aerial Photography for the Main Eight Hawaiian Islands: Molokai (328c-0516)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Habitat maps of the main Hawaiian Islands were created by visual interpretation of aerial photos and hyperspectral imagery using the Habitat Digitizer extension....

  19. C-CAP United States Virgin Islands, St. John 2005-2007-Era Land Cover Change Analysis

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set contains the 2005-era and 2007-era classifications of St. John, United States Virgin Islands and can be used to analyze change. This data set utilized...

  20. Illustration of Modern Wind Turbine Ancillary Services

    DEFF Research Database (Denmark)

    Margaris, Ioannis D.; Hansen, Anca Daniela; Sørensen, Poul Ejnar

    2010-01-01

    Increasing levels of wind power penetration in modern power systems has set intensively high standards with respect to wind turbine technology during the last years. Security issues have become rather critical and operation of wind farms as conventional power plants is becoming a necessity as wind...... to power system security. An overview of ancillary services provided by wind turbine technology nowadays is provided, i.e., fault ride-through capability, reactive power supply and frequency-active power control....