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  1. Fast and Accurate Identification of Cross-Linked Peptides for the Structural Analysis of Large Protein Complexes and Elucidation of Interaction Networks. / Tahir, Salman; Bukowski-Wills, Jimi-Carlo; Rasmussen, Morten; Rappsilber, Juri

    DEFF Research Database (Denmark)

    Rasmussen, Morten

    that occurs when all peptide-peptide combinations are considered in a database search. We have developed an algorithm that finds and validates cross-linked peptides in an efficient and scalable manner by adopting a number of principles both biological and computational.   Methods We make use of a high...... peptide-peptide-combinations becomes infeasible to compute. We utilize a high accuracy library of >1000 synthetic peptides to understand the fragmentation behaviour of cross-linked peptides. 92.4% of the most intense peaks from the annotated spectra of this library occur due to single fragmentation....... Moreover, we note that 92.5% of the top peaks belong to one of the two peptides comprising a cross-linked pair. Using this information, we are able to reduce the complexity of the cross-link search to a linear search. The presence of a primary, more dominant, peptide that fragments better than...

  2. Erik Rasmussen

    DEFF Research Database (Denmark)

    Lippert-Rasmussen, Kasper

    Erik Rasmussen (1917-1995) anses af mange for at være dansk statskundskabs ophavsmand. Som en af landets to første professorer i faget var han i årene 1959-1984 med til at opbygge Institut for Statskundskab ved Aarhus Universitet. Hans lærebog, Komparativ Politik (1968-69), var obligatorisk for de...... første generationer af cand. scient. pol.’er og med til at skole disse i den videnskabelige værdirelativisme, strukturfunktionalismen og David Easton’s opfattelse af politik og det politiske system. I sine senere år søgte Rasmussen især at kaste et kritisk lys over, hvad han anså for at være sin samtids...... uigennemtænkte »lighedsentusiasme«. Rasmussen var historiker af uddannelse og havde et udsædvanligt bredt videnskabeligt udsyn. Gennem hele sit akademiske virke var han stærkt optaget af videnskabsteoretiske aspekter ved statskundskaben....

  3. Multiphasic presentation of Rasmussen's encephalitis

    NARCIS (Netherlands)

    Avbersek, A.; Miserocchi, A.; McEvoy, A.W.; Patel, A.V.; Aronica, E.; Blumcke, I.; Jacques, T.S.; Acheson, J.; Thom, M.; Sisodiya, S.M.

    2015-01-01

    Rasmussen's encephalitis is a rare, chronic inflammatory disorder of unknown cause, characterised by drug-resistant focal epilepsy that may rarely present in adolescence or adulthood. We present a case of Rasmussen's encephalitis with prominent recurrent fluctuation in symptoms and well-documented

  4. Erik Rasmussen, Niels Bohr og Værdirelativismen - i anledning af Kasper Lippert-Rasmussens bog om Erik Rasmussen

    DEFF Research Database (Denmark)

    Ougaard, Morten

    2015-01-01

    En svaghed ved Kasper Lippert-Rasmussens i øvrigt udmærkede bog om Erik Rasmussen er, at den forbigår den sene Rasmussens bog om komplementaritet og statskundskab. Bogen var vigtig for Rasmussen, og den bør indgå i hans faglige eftermæle. Den rummer videnskabsteoretiske argumenter af stor relevans......, ikke mindst med hensyn til værdirelativismen. Rasmussen viser, at komplementaritetsbegrebet i Bohrs vigtige men oversete filosofi kan bidrage væsentligt til at afklare teoretisk-metodiske problemer i statskundskab, herunder forholdet mellem struktur og handling og mellem mikro- og makroanalyse, samt...... ikke mindst forholdet mellem normative og kognitive udsagn. Efter mødet med Niels Bohrs filosofi står Rasmussens værdirelativisme både skarpere og stærkere end før, og Kasper Lippert-Rasmussens karakteristik af denne position som et ubegrundet dogme i dansk politologi er ikke overbevisende....

  5. Putaminal involvement in Rasmussen encephalitis

    Energy Technology Data Exchange (ETDEWEB)

    Rajesh, Bhagavatheeswaran; Ashalatha, Radhakrishnan [Sree Chitra Tirunal Institute for Medical Sciences and Technology, Department of Neurology, Trivandrum, Kerala (India); Kesavadas, Chandrasekharan; Thomas, Bejoy [Sree Chitra Tirunal Institute for Medical Sciences and Technology, Department of Imaging Sciences and Interventional Radiology, Trivandrum, Kerala (India)

    2006-08-15

    Rasmussen encephalitis (RE) is a rare devastating disease of childhood causing progressive neurological deficits and intractable seizures, typically affecting one hemisphere. Characteristic MRI features include progressive unihemispheric focal cortical atrophy and grey- or white-matter high-signal changes and basal ganglion involvement, particularly of the caudate nucleus. To analyse the pattern of involvement of different brain structures in a series of patients with RE and to attempt clinical correlation. We reviewed the medical records and neuroimaging data of 12 patients diagnosed with RE satisfying the European Consensus Statement diagnostic criteria. The disease manifested as seizures in all patients and was refractory; epilepsia partialis continua was a notable feature (nine patients). Hemiparesis of varying grades was noted in all but one patient; none had extrapyramidal signs. Neuroimaging showed cortical involvement in the insular/periinsular regions in 11 patients. Caudate atrophy was noted in ten patients. Putaminal atrophy was seen in nine patients, six of whom had additional hyperintense signal changes. Our study highlights frequent putaminal atrophy and signal changes in RE, which suggests a more extensive basal ganglion involvement than emphasized previously. Recognition of putaminal changes may be a useful additional tool in the radiological diagnosis of RE. (orig.)

  6. Rasmussen and the boundaries of empirical evaluation.

    Science.gov (United States)

    Sanderson, Penelope; Burns, Catherine

    2017-03-01

    In this special issue, many of the papers focus on Rasmussen's analytic contributions to the understanding of work in complex sociotechnical systems. Work is analysed for the purpose of developing new designs that can improve the nature of that work. The evaluation of such designs was a key part of Rasmussen's program, yet he was often sceptical of the claims made for the generalizability of empirical studies. To tackle this problem, he extended his work analysis framework to provide a way of thinking about empirical evaluation. As authors of this paper, we come from two different backgrounds-systems engineering in the case of Burns, and engineering psychology in the case of Sanderson-and over the decades of our respective research programs, we have both performed many empirical investigations: field investigations, simulation studies, and behavioural laboratory experiments. Rasmussen's scepticism-and his writings on the issue-have stimulated and shaped our own research. In this brief paper we present our interpretation of Rasmussen's perspective, we provide examples how our research sits within Rasmussen's framework of constraints defining boundary conditions for experiments, and we draw conclusions for the future. Copyright © 2016. Published by Elsevier Ltd.

  7. The 3D Lagrangian Integral Method. Henrik Koblitz Rasmussen

    DEFF Research Database (Denmark)

    Rasmussen, Henrik Koblitz

    2003-01-01

    in H.K. Rasmussen, JNNFM, Vol. 84, p. 217-232 (1999), H.K. Rasmussen, JNNFM, Vol. 92, p. 227-243 (2000) and H.K. Rasmussen, JNNFM, Vol. 106, p. 107-120 (2002), for respectively the Upper Convected Maxwell, the Rivlin-Sawyers (includes the K-BKZ) and a generalized Molecular Stress Function (MSF...

  8. Anders Fogh Rasmussen : Riigi suurus sõltub poliitikutest / Anders Fogh Rasmussen ; interv. Marianne Mikko

    Index Scriptorium Estoniae

    Rasmussen, Anders Fogh

    2003-01-01

    Taani peaminister Anders Fogh Rasmussen vastab küsimustele, mis puudutavad Balti riikide koalitsiooni Põhjala riikidega EL-i otsuste langetamisel, Taani-Eesti ühishuve, EL-i liitumiskõneluste lõppu 2002. aasta detsembris, EL põhiseadusliku lepingu mustandit, EL-i ülemkogu esimehe võimupiire, võimalike koalitsioonide teket EL-is, suhtumist viisavabadusse Venemaaga, rahvahääletust Eestis ja Rootsis

  9. Rasmussen keeldus kinnitamast NATO-kõlakaid / Hendrik Vosman

    Index Scriptorium Estoniae

    Vosman, Hendrik

    2009-01-01

    Tallinna külastas Taani peaminister Anders Fogh Rasmussen, kes kohtus peaminister Andrus Ansipi ja president Toomas Hendrik Ilvesega. Eesti riigipea andis A. F. Rasmussenile üle Maarjamaa Risti I klassi teenetemärgi

  10. Rasmussen's legacy: A paradigm change in engineering for safety.

    Science.gov (United States)

    Leveson, Nancy G

    2017-03-01

    This paper describes three applications of Rasmussen's idea to systems engineering practice. The first is the application of the abstraction hierarchy to engineering specifications, particularly requirements specification. The second is the use of Rasmussen's ideas in safety modeling and analysis to create a new, more powerful type of accident causation model that extends traditional models to better handle human-operated, software-intensive, sociotechnical systems. Because this new model has a formal, mathematical foundation built on systems theory (as was Rasmussen's original model), new modeling and analysis tools become possible. The third application is to engineering hazard analysis. Engineers have traditionally either omitted human from consideration in system hazard analysis or have treated them rather superficially, for example, that they behave randomly. Applying Rasmussen's model of human error to a powerful new hazard analysis technique allows human behavior to be included in engineering hazard analysis. Copyright © 2016 Elsevier Ltd. All rights reserved.

  11. Recurring themes in the legacy of Jens Rasmussen

    DEFF Research Database (Denmark)

    Waterson, Patrick; Le Coze, Jean-Christophe; Andersen, Henning Boje

    2016-01-01

    The work of Jens Rasmussen over the course of the last half century represents some of the most influential contributions to the fields of cognitive science, human factors, ergonomics and safety science. His work has inspired researchers and practitioners in a number of fields including psycholog...

  12. 'Remixing Rasmussen': The evolution of Accimaps within systemic accident analysis.

    Science.gov (United States)

    Waterson, Patrick; Jenkins, Daniel P; Salmon, Paul M; Underwood, Peter

    2017-03-01

    Throughout Jens Rasmussen's career there has been a continued emphasis on the development of methods, techniques and tools for accident analysis and investigation. In this paper we focus on the evolution and development of one specific example, namely Accimaps and their use for accident analysis. We describe the origins of Accimaps followed by a review of 27 studies which have applied and adapted Accimaps over the period 2000-2015 to a range of domains and types of accident. Aside from demonstrating the versatility and popularity of the method, part of the motivation for the review of the use of Accimaps is to address the question of what constitutes a sound, usable, valid and reliable approach to systemic accident analysis. The findings from the review demonstrate continuity with the work carried out by Rasmussen, as well as significant variation (e.g., changes to the Accimap, used of additional theoretical and practice-oriented perspectives on safety). We conclude the paper with some speculations regarding future extension and adaptation of the Accimap approach including the possibility of using hybrid models for accident analysis. Copyright © 2016 Elsevier Ltd. All rights reserved.

  13. Subacute sclerosing panencephalitis resembling Rasmussen's encephalitis on magnetic resonance imaging.

    Science.gov (United States)

    Jakkani, Ravi Kanth; Sureka, Jyoti; Panwar, Sanuj

    2015-09-01

    Subacute sclerosing panencephalitis (SSPE) is a rare, slowly progressing but invariably fatal disease that is related to a prior measles virus infection and most commonly affects paediatric patients. Magnetic resonance (MR) imaging is the modality of choice for determining such changes in white matter. SSPE typically demonstrates bilateral but asymmetric periventricular and subcortical white matter involvement. We herein report a rare case of unilateral white matter involvement in a 13-year-old boy with SSPE that closely simulated Rasmussen's encephalitis. To the best of our knowledge, this is the first report of an atypical presentation on MR imaging in which SSPE was a rare cause of unilateral brain parenchymal involvement in a patient with intractable seizures.

  14. A Case of Rasmussen Encephalitis: The Differential Diagnoses and Role of Diagnostic Imaging

    Directory of Open Access Journals (Sweden)

    Binoj Varghese

    2014-01-01

    Full Text Available Rasmussen encephalitis is an extremely rare chronic inflammatory neurodegenerative disease affecting a single cerebral hemisphere, causing progressive neurological deterioration and intractable seizures. Imaging plays an important role in diagnosis by demonstrating focal or unihemispheric involvement and excluding other possible causes. Here, we report a case of Rasmussen encephalitis with an update on recent diagnostic criteria and emphasis on differential diagnoses which can be excluded on imaging.

  15. FOCAL EPILEPTIC MYOCLONUS IN KOZHEVNIKOV–RASMUSSEN SYNDROME

    Directory of Open Access Journals (Sweden)

    N. E. Kvaskova

    2016-01-01

    Full Text Available The article presents the clinical, electroencephalographic (EEG and neuroimaging features, as well as the results of treatment of patients with focal epileptic myoclonus (FEM with the Kozhevnikov–Rasmussen syndrome (KRS. FEM in KRS-patients was identified in 11 cases, accounting for 0.9 % of all the cases of epilepsy with the onset of seizures up to 18 years (n = 1261. The age at onset of KRS ranged from 3 to 21 years (average – 9.2 ± 5.7 years. In the active period of the disease of all patients in the clinical picture the active FEM appeared and increasing frequency of the secondary generalized seizures (SGS. In addition SGS and FEM, the clinical picture of the disease in most patients (91 % the focal motor (clonic and the somatosensory focal seizures were observed. As the disease progressed, the FEM became more pronounced in frequency and intensity, seized more muscle groups, localizing mainly in the muscles of the trunk and limbs. The typical EEG pattern of FEM patients with KRS was regional epileptiform activity that occurs in the structure of the continued regional slowing localizing maximum of the fronto-central-temporal region. During the magnetic resonance tomography of the brain in dynamics all the patients observed the increase in total cortical hemiatrophy. In all the cases, the appointment of antiepileptic therapy resulted in a slowing of the FEM, however, a complete remission was reached at none of the patients. Two patients were made surgical treatment of epilepsy. In one case remission of epileptic seizures was observed after right-side hemispherotomy. Our study showed that FEM is very resistant type of epileptic seizures. This fact calls for the identification of the FEM at the early stages of the disease with the purpose to improve the prognosis, as well as for an earlier surgical treatment.

  16. "Naturfolk" i teori og praksis: skildringen av samene og den nordlige naturen i Knud Rasmussens Lapland

    Directory of Open Access Journals (Sweden)

    Fredrik Christian Brøgger

    2014-07-01

    Full Text Available This article focuses on the portrayal of reindeer Sami in the Danish explorer Knud Rasmussen's early book Lapland from 1907, a work that has received relatively little attention in Rasmussen scholarship. His characterizations of the Sami reflect conventional, paternalistic ideas of race and culture at the turn of the century as well as romantic-sentimental conceptions of indigenous peoples as noble savages. Rasmussen is a lively storyteller, however, and the immediacy and vividness of his depictions simultaneously open up for perspectives that, at least partly, serve to undermine traditional stereotypes. If read closely, Rasmussen's narrative evinces clear tensions between its conventional generalizations about the reindeer Sami as an indigenous people and the direct, phenomenological descriptions that are the products of Rasmussen's actual encounter with them. At the same time his instinctive sympathy for the Sami is enlarged by his own, deeply personal yearning for a life style and culture grounded in Northern cold and winter, which he encountered growing up in Greenland and which runs like a leitmotif through all his writing.

  17. MRI findings in the diagnosis and monitoring of rasmussen's encephalitis Achados de RM no diagnóstico e monitorização da encefalite de Rasmussen

    Directory of Open Access Journals (Sweden)

    Andréia V. Faria

    2009-09-01

    Full Text Available Rasmussen's encephalitis is a devastating syndrome of multifocal brain dysfunction and focal seizures. Magnetic resonance (MR findings, associated with clinical data and electroencephalogram (EEG, may indicate the diagnosis and could be an indicative of prognosis. We studied 5 patients with Rasmussen's encephalitis, assessing clinical history and MR images. All patients had refractory focal seizures with a predominant motor component associated with hemispheric atrophy, that was proportional to severity of disease and neurological deficits in these patients. Gray and white matter abnormal signal on T2 MR images were found in patients who had hemiparesis. It was not related to the duration of the disease but to aggressiveness. MR proton spectroscopy in severe disease showed lactate and choline increase and decreased NAA, reflecting neuronal and axonal loss, gliosis and elevated membrane turnover and recent - crisis (not controlled. MR studies, in addition to help in diagnosis, may be useful for monitoring metabolic changes and progression of disease in Rasmussen's encephalitis.A encefalite de Rasmussen é uma devastadora síndrome com disfunção cerebral multifocal e convulsões focais. Achados de ressonância magnética (RM, associados aos dados clínicos e de eletrencefalograma (EEG, podem indicar o diagnóstico e podem ser indicativos de prognóstico. Foram estudados 5 pacientes com encefalite de Rasmussen, avaliando a história clínica e imagens de RM. Todos os pacientes apresentavam crises epilépticas focais refratárias com componente predominantemente motor associadas à atrofia hemisférica, que foi proporcional à gravidade da doença e déficits neurológicos nestes pacientes. Alteração da intensidade de sinal nas substâncias branca e cinzenta, nas sequências ponderadas em T2, foram encontradas nos pacientes com hemiparesia. Ela não estava relacionada com a duração da doença, mas à severidade. A espectroscopia de pr

  18. Functional hemispherotomy in Rasmussen syndrome in the absence of classic MRI findings.

    Science.gov (United States)

    Nagahama, Yasunori; Joshi, Charuta; Dlouhy, Brian; Wu, Angela Y; Abel, Taylor J; Baumbach, Gary; Kawasaki, Hiroto

    2017-01-01

    A 7-year-old previously healthy girl presented with a left-sided focal seizure without impaired consciousness and subsequently developed epilepsia partialis continua. Initial MRI was normal, and the subsequent images only showed a focal T2/FLAIR hyperintense area without cortical atrophy. She was diagnosed with Rasmussen syndrome by pathology and promptly treated with functional hemispherotomy. Rasmussen syndrome is a rare progressive neurological disorder, the only definitive cure for which is hemispheric disconnection. The disease presents a management dilemma, especially early in disease course without characteristic neuroimaging features. A high index of suspicion, multidisciplinary approach, and clear timely communication with the family are critical.

  19. Functional hemispherotomy in Rasmussen syndrome in the absence of classic MRI findings

    Directory of Open Access Journals (Sweden)

    Yasunori Nagahama

    2017-01-01

    Full Text Available A 7-year-old previously healthy girl presented with a left-sided focal seizure without impaired consciousness and subsequently developed epilepsia partialis continua. Initial MRI was normal, and the subsequent images only showed a focal T2/FLAIR hyperintense area without cortical atrophy. She was diagnosed with Rasmussen syndrome by pathology and promptly treated with functional hemispherotomy. Rasmussen syndrome is a rare progressive neurological disorder, the only definitive cure for which is hemispheric disconnection. The disease presents a management dilemma, especially early in disease course without characteristic neuroimaging features. A high index of suspicion, multidisciplinary approach, and clear timely communication with the family are critical.

  20. Provável síndrome de Rasmussen: relato de caso

    Directory of Open Access Journals (Sweden)

    CORAL LUÍZ CARLOS

    1999-01-01

    Full Text Available A síndrome de encefalite crônica com epilepsia (síndrome de Rasmussen ocorre tipicamente em crianças e é caracterizada pelo desenvolvimento de epilepsia focal intratável, hemiparesia progressiva e deterioração intelectual. A etiologia é desconhecida e as anormalidades patológicas variam com a fase da doença. Relatamos o caso de um paciente jovem, com 17 anos de idade, com apresentação clínica da provável síndrome de Rasmussen. Discutimos a etiologia e o tratamento da patologia.

  1. Serial MRI and MRS studies with unusual findings in Rasmussen's encephalitis

    Energy Technology Data Exchange (ETDEWEB)

    Tuerkdogan-Soezueer, D. [Department of Pediatric Neurology, Institute of Neurological Sciences, Marmara University, Istanbul (Turkey); Oezek, M.M.; Pamir, M.N. [Department of Neurosurgery, Institute of Neurological Sciences, Marmara University, Istanbul (Turkey); Sav, A. [Department of Pathology, Institute of Neurological Sciences, Marmara University, Istanbul (Turkey); Dincer, A. [Radyomar MR Center, Istanbul (Turkey)

    2000-06-01

    Rasmussen's syndrome is characterized by intractable seizures and progressive neuropsychiatric deterioration secondary to unilateral cortical inflammation and tissue destruction. Diagnosis of Rasmussen's syndrome in the early phase depends mainly on the clinical features. Neuroimaging and histopathologic examinations may not be specific during this period. We report a case of Rasmussen's syndrome followed by serial MRI and magnetic resonance spectroscopy (MRS) studies over a 3- to 16-month period. A healthy 6-year-old boy presented with focal motor seizures. An MRI study demonstrated prominent enlargement and T2 hyperintensity of the left mesial temporal lobe and perisylvian region. This early finding evolved to volume loss and later progressive atrophy of the ipsilateral hemisphere when epilepsia partialis continua occurred. Being aware of those early MRI features in a patient with increasing frequency of focal motor seizures should suggest Rasmussen's syndrome. In addition, we found prominently increased myoinositol concentration in atrophic cortex which might reflect increased gliosis in the late period of the disease. (orig.)

  2. Supporting the human life-raft in confronting the juggernaut of technology: Jens Rasmussen, 1961-1986.

    Science.gov (United States)

    Kant, Vivek

    2017-03-01

    Jens Rasmussen's contribution to the field of human factors and ergonomics has had a lasting impact. Six prominent interrelated themes can be extracted from his research between 1961 and 1986. These themes form the basis of an engineering epistemology which is best manifested by his abstraction hierarchy. Further, Rasmussen reformulated technical reliability using systems language to enable a proper human-machine fit. To understand the concept of human-machine fit, he included the operator as a central component in the system to enhance system safety. This change resulted in the application of a qualitative and categorical approach for human-machine interaction design. Finally, Rasmussen's insistence on a working philosophy of systems design as being a joint responsibility of operators and designers provided the basis for averting errors and ensuring safe and correct system functioning. Copyright © 2016 Elsevier Ltd. All rights reserved.

  3. What is the fate of disconnected brain tissue in a child with Rasmussen syndrome? A case report

    Energy Technology Data Exchange (ETDEWEB)

    Kim, S.J.; Park, Y.D. [Dept. of Neurology (Child), Medical Coll. of Georgia, Augusta, GA (United States); Pillai, J. [Dept. of Radiology, Medical Coll. of Georgia, Augusta, GA (United States)

    2003-04-01

    We describe a case of Rasmussen syndrome in a 7-year-old boy, presenting with epilepsia partialis continua, hemiplegia, and progressive mental deterioration. The initial MRI examination was normal, followed by progressive left hemispheric cortical atrophy and abnormal high signal intensity over the left occipital, parietal, and cingulate gyral areas over an 18-month period. On the basis of the clinical diagnosis and biopsy findings of Rasmussen syndrome, functional hemispherectomy was carried out at 7.5 years of age with alleviation of clinical seizures for the following 44 months. The follow-up MRI demonstrated atrophic changes involving the remaining left hemisphere with increased signal and cortical volume loss, as well as the absence of abnormal signal in the right hemisphere at 10 years of age. Our MRI findings are consistent with the progression of Rasmussen syndrome in the ipsilateral hemisphere even after functional-hemispherectomy without clinical seizures. (orig.)

  4. Rasmussen's Encephalitis

    Science.gov (United States)

    ... severe seizures, loss of motor skills and speech, paralysis on one side of the body (hemiparesis), inflammation of the brain (encephalitis), and mental deterioration. Most individuals with Rasmussen’s ...

  5. Rasmussen's encephalitis

    African Journals Online (AJOL)

    2011-03-08

    Mar 8, 2011 ... after the second ictus of which patient had to stop school. He did not exhibit neuropsychiatric features. Clinical examination revealed a mildly pale, febrile, mildly dehydrated lanky adolescent. He was not icteric and his peripheral lymph nodes were not enlarged. He was conscious and alert with receptive ...

  6. 76 FR 11259 - Notice of Intent To Prepare an Environmental Impact Statement for the Proposed Rasmussen Valley...

    Science.gov (United States)

    2011-03-01

    ... Environmental Impact Statement for the Proposed Rasmussen Valley Mine and Reclamation Plan, Caribou County, ID... Environmental Impact Statement (EIS) to determine and analyze the effects of a proposed phosphate mine and... has proposed management practices in its mine and reclamation plan to reduce environmental impacts...

  7. Reflecting on Jens Rasmussen's legacy (2) behind and beyond, a 'constructivist turn'.

    Science.gov (United States)

    Le Coze, Jean-Christophe

    2017-03-01

    This article is the second part of a study on the legacy of Jens Rasmussen. The first article, subtitled 'A Strong Program for a Hard Problem', looks back on his 30 years of scientific contribution, from 1969 to 2000. This second article explores and investigates some of the intellectual roots which influenced his thinking, using them as a basis to understand some limits and move forward. Indeed, historically oriented studies such as this one are not only tributes to researchers, but a way to differentiate and contrast our present situation with the past in order to integrate contemporary trends, be they theoretical or empirical, or oriented towards research and new models. In the first section of this article, I offer a synthesis of the background covered in the previous article, but I use a tree here as a graphical complement. Branches of the tree show the many fruitful directions opened by Jens Rasmussen, directions which inspired many researchers. In the second part, I address what I believe to be behind this wealth of engineering legacy: cybernetics. I contend that cybernetics has had a profound influence on his thinking and provided him key principles for his inspiring and successful models. To develop the tree image, one might say that cybernetics is the trunk of the tree. Finally, in the third part, I take the opportunity to explore the relevance of extending and sensitising his program to constructivist discourses. After an introduction to this discourse, identifying four types of constructivisms (cognitive, social, epistemological and anthropological), I characterise this move as a 'constructivist turn'. Copyright © 2015 Elsevier Ltd. All rights reserved.

  8. Clinical application and evaluation of the Bien diagnostic criteria for Rasmussen encephalitis.

    Science.gov (United States)

    Olson, Heather E; Lechpammer, Mirna; Prabhu, Sanjay P; Ciarlini, Pedro D S C; Poduri, Annapurna; Gooty, Vasu D; Anjum, Muhammad W; Gorman, Mark P; Loddenkemper, Tobias

    2013-10-01

    The 2005 diagnostic criteria for Rasmussen encephalitis (RE) are based on seizures, clinical deficits, electroencephalography (EEG), neuroimaging, and pathology (Brain, 128, 2005, 451). We applied these criteria to patients evaluated for RE and epilepsy surgery controls to determine the sensitivity, specificity, and positive and negative predictive values (PPVs, NPVs) using pathology as the gold standard. We identified patients evaluated for RE based on medical records from 1993 to 2011. Fifty-two control patients with refractory epilepsy, unilateral magnetic resonance imaging (MRI) changes, and biopsies were selected from an epilepsy surgery database from matching years. Patients meeting all three of group A and/or two of three group B criteria were classified as meeting full criteria (positive). Patients not meeting full criteria were classified as negative. When available, pathology findings were re-reviewed with neuropathologists, and MRI imaging was re-reviewed with a neuroradiologist. RE was considered in the differential diagnosis for 82 patients, of whom 35 had biopsies. Twenty patients met full criteria (positive) without another explanation, including seven for whom biopsy was required to meet criteria and one in whom another etiology was identified. Two patients met full criteria but had another explanation. Thirty-five met partial criteria (negative), of whom 14 had another etiology identified. Twenty-five met no criteria (negative). The diagnostic criteria had a sensitivity of 81% with four false negatives (criteria-negative, biopsy-positive) when compared to pathology as a gold standard. Five false positives (criteria positive, biopsy negative) had identifiable alternate diagnoses. The 2005 Bien clinical diagnostic criteria for RE have reasonably high sensitivity and specificity and good clinical-pathologic correlation in most cases. We suggest modification of the criteria to allow inclusion of cases with well-described but less common features

  9. Mechanisms of epileptogenesis in pediatric epileptic syndromes: Rasmussen encephalitis, infantile spasms, and febrile infection-related epilepsy syndrome (FIRES).

    Science.gov (United States)

    Pardo, Carlos A; Nabbout, Rima; Galanopoulou, Aristea S

    2014-04-01

    The mechanisms of epileptogenesis in pediatric epileptic syndromes are diverse, and may involve disturbances of neurodevelopmental trajectories, synaptic homeostasis, and cortical connectivity, which may occur during brain development, early infancy, or childhood. Although genetic or structural/metabolic factors are frequently associated with age-specific epileptic syndromes, such as infantile spasms and West syndrome, other syndromes may be determined by the effect of immunopathogenic mechanisms or energy-dependent processes in response to environmental challenges, such as infections or fever in normally-developed children during early or late childhood. Immune-mediated mechanisms have been suggested in selected pediatric epileptic syndromes in which acute and rapidly progressive encephalopathies preceded by fever and/or infections, such as febrile infection-related epilepsy syndrome, or in chronic progressive encephalopathies, such as Rasmussen encephalitis. A definite involvement of adaptive and innate immune mechanisms driven by cytotoxic CD8(+) T lymphocytes and neuroglial responses has been demonstrated in Rasmussen encephalitis, although the triggering factor of these responses remains unknown. Although the beneficial response to steroids and adrenocorticotropic hormone of infantile spasms, or preceding fever or infection in FIRES, may support a potential role of neuroinflammation as pathogenic factor, no definite demonstration of such involvement has been achieved, and genetic or metabolic factors are suspected. A major challenge for the future is discovering pathogenic mechanisms and etiological factors that facilitate the introduction of novel targets for drug intervention aimed at interfering with the disease mechanisms, therefore providing putative disease-modifying treatments in these pediatric epileptic syndromes.

  10. Teaching Narrative Writing Using Comics: Delainey and Rasmussen, the Creators of "Betty," Share Their Composing Strategies as Rich Literacy Resources for Elementary Teachers

    Science.gov (United States)

    Nixon, Rhonda

    2012-01-01

    The author explores how comics texts and writing practices are rich literacy resources for educators. Few studies report on how teachers explore such texts and practices in their classrooms. The author examines how drawing improves students' narrative writing and presents findings from a 7-month case study of Delainey and Rasmussen's collaborative…

  11. Slowly progressive hemiparesis in childhood as a consequence of Rasmussen encephalitis without or with delayed-onset seizures.

    Science.gov (United States)

    Bien, C G; Elger, C E; Leitner, Y; Gomori, M; Ran, B; Urbach, H; Wilken, B; Korn-Lubetzki, I

    2007-04-01

    Five young children developed slowly progressive hemiparesis as the initial manifestation of Rasmussen encephalitis (RE). Three have remained seizure free over an observational period of 1.3-1.9 years. In the remaining two patients, seizures occurred after 0.5 and 0.6 years respectively. We suggest that RE might be presently underdiagnosed and should be suspected in cases of new onset hemiparesis. In this series, three out of five patients showed oligoclonal bands on examination of cerebrospinal fluid (CSF) which represented additional diagnostic hints towards an immune-mediated condition. According to recently published formal diagnostic criteria, evidence of progressive cerebral hemiatrophy or bioptic identification of RE-typical inflammation confirms the diagnosis in such cases. Long-term immunotherapy is recommended in order to prevent further tissue loss and functional decline.

  12. CD8+ T-cell pathogenicity in Rasmussen encephalitis elucidated by large-scale T-cell receptor sequencing

    Science.gov (United States)

    Schneider-Hohendorf, Tilman; Mohan, Hema; Bien, Christian G.; Breuer, Johanna; Becker, Albert; Görlich, Dennis; Kuhlmann, Tanja; Widman, Guido; Herich, Sebastian; Elpers, Christiane; Melzer, Nico; Dornmair, Klaus; Kurlemann, Gerhard; Wiendl, Heinz; Schwab, Nicholas

    2016-01-01

    Rasmussen encephalitis (RE) is a rare paediatric epilepsy with uni-hemispheric inflammation and progressive neurological deficits. To elucidate RE immunopathology, we applied T-cell receptor (TCR) sequencing to blood (n=23), cerebrospinal fluid (n=2) and brain biopsies (n=5) of RE patients, and paediatric controls. RE patients present with peripheral CD8+ T-cell expansion and its strength correlates with disease severity. In addition, RE is the only paediatric epilepsy with prominent T-cell expansions in the CNS. Consistently, common clones are shared between RE patients, who also share MHC-I alleles. Public RE clones share Vβ genes and length of the CDR3. Rituximab/natalizumab/basiliximab treatment does not change TCR diversity, stem cell transplantation replaces the TCR repertoire with minimal overlap between donor and recipient, as observed in individual cases. Our study supports the hypothesis of an antigen-specific attack of peripherally expanded CD8+ lymphocytes against CNS structures in RE, which might be ameliorated by restricting access to the CNS. PMID:27040081

  13. "Jamil Perkersen Nielsen Rasmussen"

    DEFF Research Database (Denmark)

    Nørreby, Thomas Rørbeck

    Denne afhandling omhandler en ung mand fra Amager ved navn Jamil og hans sociale og sproglige praksisser. I min undersøgelse fokuserer jeg på, hvorledes Jamil konstruerer og forhandler etniske identiteter i skole- og fritidsmiljøer og på Facebook. Min undersøgelse er baseret på et etnografisk fel...

  14. In Rasmussen Encephalitis, Hemichannels Associated with Microglial Activation are linked to Cortical Pyramidal Neuron Coupling: A Possible Mechanism for Cellular Hyperexcitability

    Science.gov (United States)

    Cepeda, Carlos; Chang, Julia W.; Owens, Geoffrey C.; Huynh, My N.; Chen, Jane Y.; Tran, Conny; Vinters, Harry V.; Levine, Michael S.; Mathern, Gary W.

    2014-01-01

    Aims Rasmussen encephalitis (RE) is a rare but devastating condition, mainly in children, characterized by sustained brain inflammation, atrophy of one cerebral hemisphere, epilepsy and progressive cognitive deterioration. The etiology of RE-induced seizures associated with the inflammatory process remains unknown. Methods Cortical tissue samples from children undergoing surgical resections for the treatment of RE (n=16) and non-RE (n=12) were compared using electrophysiological, morphological, and immunohistochemical techniques to examine neuronal properties and the relationship with microglial activation using the specific microglia/macrophage calcium-binding protein, IBA1 in conjunction with connexins and pannexin expression. Results Compared with non-RE cases, pyramidal neurons from RE cases displayed increased cell capacitance and reduced input resistance. However, neuronal somatic areas were not increased in size. Instead, intracellular injection of biocytin led to increased dye-coupling between neurons from RE cases. By Western blot, expression of IBA1 and pannexin was increased while connexin 32 was decreased in RE cases compared with non-RE cases. IBA1 immunostaining overlapped with pannexin and connexin 36 in RE cases. Conclusions In RE, these results support the notion that a possible mechanism for cellular hyperexcitability may be related to increased intercellular coupling from pannexin linked to increased microglial activation. Such findings suggest that a possible anti-seizure treatment for RE may involve the use of gap junction blockers. PMID:25438677

  15. Rasmussen kom i klemme med firmaets kreditkort

    DEFF Research Database (Denmark)

    Langsted, Lars Bo

    2004-01-01

    Højesteret har netop stemplet et aftalevilkår i kortindehaverreglerne for Eurocard som værende i strid med redelig handlemåde. Samtidig har afgørelsen ført til en klart forbedret retsstilling for ansatte, der anvender firmakort....

  16. Medierne og Lars Løkke Rasmussen

    DEFF Research Database (Denmark)

    Dindler, Camilla

    2014-01-01

    Hvad gik galt med nyhedsmedierne i de forgangne ugers Løkke-sag? Kritikerne mener, at pressens håndtering blev et eksempel på uprofessionel omgang med anonyme kilder, ensidighed og uholdbare forudsigelser. Hvordan kunne dette ske?...

  17. Ib & Jørgen Rasmussen Arkitekter

    DEFF Research Database (Denmark)

    Lund, Nils-Ole

    2007-01-01

    1960’erne og 1970’erne var der stort set ikke den arkitektkonkurrence, hvor tvillingerne Ib & Jørgen ikke fik en placering eller et indkøb, og dette sprudlende og talentfulde arkitektpar har nu fået den portrætbog, de så længe har fortjent. Henved 100 énfamiliehuse og markante hovedværker som Sol...

  18. Rasmussen's encephalitis | Dawodu | Nigerian Journal of Clinical ...

    African Journals Online (AJOL)

    complicated meningo.encephalitis and the third episode was associated with receptive aphasia, hemiparesis and intellectual impairment. Neuroimaging studies revealed cerebellar atrophy and infarction of territory of the middle cerebral artery.

  19. Rasmussen ei näe Taanile euroliidus erandeid / Toomas Hendrik Ilves, Anders Fogh Rasmussen

    Index Scriptorium Estoniae

    Ilves, Toomas Hendrik, 1953-

    2003-01-01

    Eesti endise välisministri Toomas Hendrik Ilvese ja Taani peaministri Anders Fogh Rasmusseni televestlus Taani aktiivsest välispoliitikast, NATO laienemisest ja arengust, Taani kuulumisest EL-i, Euroopa riikide koostööst, euro kasutuselevõtust Taanis

  20. Critical Exchange: Avoiding Schooling Taboos--A Reply to Rasmussen

    Science.gov (United States)

    Stern, Julian

    2017-01-01

    This paper is a reply to Mary L. Rasumussen's paper, "Critical Exchange: Religion and Schooling: What Should Their Relationship Be?" In this paper, Julian Stern makes three claims: (1) the need for a messy conversation; (2) the need to include "whole" people in schools; and (3) the need to consider existentially significant…

  1. Rasmussen reassures on NATO security guarantees / Rokas M. Tracevskis

    Index Scriptorium Estoniae

    Tracevskis, Rokas M.

    2009-01-01

    NATO peasekretäri Anders Fogh Rasmusseni Läti visiidist, mille käigus külastas ta Šiauliai lähedal asuvat Zokniai õhubaasi ja kohtus Leedu presidendi Dalia Grybauskaite, peaminister Andrius Kubiliuse ja välisminister Vygaudas Usackasega

  2. Lõpp naiste ja meeste palgavahele / Poul Nyrup Rasmussen, Marianne Mikko

    Index Scriptorium Estoniae

    Rasmussen, Poul Nyrup

    2007-01-01

    Euroopa sotsiaaldemokraadid alustavad võitlust meeste ja naiste vahel püsiva palgaerinevusega. Euroopa Sotsiaaldemokraatliku Partei esimehe ja Euroopa Sotsiaaldemokraatliku Partei naisühenduse juhatuse liikme sõnul juhitakse tähelepanu ebaõiglusele, andes 22. veebruarile erilise tähenduse. See on päev, kui naissoost töötajad alustavad tõsist palgateemalist dialoogi oma tööandjate ja kolleegidega

  3. Rheological behaviour of polyethylene with peroxide crosslinking agent. Ismaeil Ghasemi, Peter Szabo and Henrik Koblitz Rasmussen

    DEFF Research Database (Denmark)

    Rasmussen, Henrik K.; Ghasemi, Ismaeil; Szabo, Peter

    2003-01-01

    One of the most important post-reactor modifications of polyethylene is cross-linking. Cross-linking improves some properties of polyethylene such as: environmental stress cracking resistance (ECSR), chemical and abrasion resistance, service temperature etc. In this study the rheological variatio...... at 150,160 and 170°C. The aim of the present work is to determine the viscosity in terms of the degree of cross-linking of LDPE in isothermal conditions by a combination of DSC and creep tests.......One of the most important post-reactor modifications of polyethylene is cross-linking. Cross-linking improves some properties of polyethylene such as: environmental stress cracking resistance (ECSR), chemical and abrasion resistance, service temperature etc. In this study the rheological variation...... due to a peroxide cross-linking reaction of low-density polyethylene (LDPE) was tracked by a combination of creep tests and differential scanning calorimetry (DSC) tests in isothermal conditions. The peroxide was di-cumyl peroxide and its concentration was 2 wt%. The experiments were carried out...

  4. Reply to Ira Rabin’s Comment on our paper Rasmussen et al.

    NARCIS (Netherlands)

    Rasmussen, Kaare Lund; Tenorio, Anna Lluveras; Bonaduce, Ilaria; Colombini, Maria Perla; Birolo, Leila; Galano, Eugenio; Amoresano, Angela; Doudna, Greg; Bond, Andrew D.; Palleschi, Vincenzo; Lorenzetti, Giulia; Legnaioli, Stefano; van der Plicht, Johannes; Gunneweg, Jan

    2012-01-01

    In the Comment by Dr. I. Rabin from Bundesanstalt für Materialforschung und -prüfung in Berlin are stated many conjectures and apparent guesses contradicting several of our interpretations. Most of Rabin’s ‘guesses’ and interpretations are unwarranted. Below we rebut some of the misinterpretations

  5. Exposiciones en la Biblioteca Luis Ángel Arango: Irene Balas y Henry Rasmussen

    Directory of Open Access Journals (Sweden)

    Luis Borobio

    1960-06-01

    Full Text Available La lluvia que cae sobre un estanque rompe los reflejos multicolores en infinitas formas caprichosas, cambiantes y siempre inéditas, que desaparecen y se renuevan sin que quizá las hayamos advertido. El sol ensaya en las nubes -espontáneamente modeladas por el viento- irisaciones insospechadas que nunca se repiten.

  6. Espen Rasmussen: need on pildid, mida soovite, et poleks kunagi pildistatud / intervjueerinud Hanne Mathisen

    Index Scriptorium Estoniae

    Rasmussen, Espen, 1976-

    2011-01-01

    Intervjuu norra fotograafiga, kelle 33 fotot saab 13.-23. juunini näha Tallinnas Rotermanni kvartalis, juunis veel Valgas ja Narvas. Fotod on pildistatud viimase seitsme aasta jooksul pagulaslaagrites Colombias, Kongo DV-s, Afganistanis, Jeemenis, Gruusias ja Süürias. Näitus toimub rahvusvahelise migratsiooniorganisatsiooni projekti "Avaliku teadlikkuse tõstmine migratsiooni- ja varjupaigatemaatikal Eestis: Pagulased?, Kes?, Miks? (PARE)" raames

  7. Elongational viscosity of narrow molar mass distribution polystyrene. Anders Bach, Kristoffer Almdal, Henrik Koblitz Rasmussen and Ole Hassager

    DEFF Research Database (Denmark)

    Rasmussen, Henrik Koblitz; Bach, Anders; Almdal, Kristoffer

    2003-01-01

    above the linear viscoelastic prediction at intermediate strains, indicating strain hardening. The steady elongational viscosities are monotone decreasing functions of elongation rate. At elongation rates larger than the inverse reptation time, the steady elongational viscosity scales linearly......Transient and steady elongational viscosity has been measured for two narrow molar mass distribution polystyrene melts of molar masses 200 000 and 390 000 by means of a filament stretching rheometer. Total Hencky strains of about five have been obtained. The transient elongational viscosity rises...... with molar mass at fixed elongation rate....

  8. Transient extensional viscosity of polymers in the filament strecthing rheometer. A. Bach, H.K. Rasmussen, O. Hassager

    DEFF Research Database (Denmark)

    Rasmussen, Henrik Koblitz; Bach, Anders; Hassager, Ole

    2002-01-01

    We investigate the transient uni-axial eextensional viscosity of polymer melts by means of a filament strecthing rheometer.......We investigate the transient uni-axial eextensional viscosity of polymer melts by means of a filament strecthing rheometer....

  9. Viscosity overshoot followed by steady state measured in uni-axial elongation of LDPE. Ole Hassager, Henrik Koblitz Rasmussen, Anders Bach and Jens Kromann Nielsen

    DEFF Research Database (Denmark)

    Rasmussen, Henrik Koblitz; Hassager, Ole; Bach, Anders

    2004-01-01

    The transient (e.g. start up of) elongational viscosity of three low-density polyethylene (LDPE) melts (BASF Lupolen 1810H, 1840D and 3020D) was measured using a filament stretching rheometer (FSR) capable of measuring at elevated temperatures. The transient uni-axial elongational viscosity showe...

  10. Transient extensional viscosity of polymer melts in the filament stretching rheometer. A. Bach, H. Bastian, M.H. Wagner, H.K. Rasmussen and O. Hassager

    DEFF Research Database (Denmark)

    Rasmussen, Henrik Koblitz; Bach, Anders; Bastian, Heike

    2002-01-01

    In many polymer processing operations, the polymer molecules becomes highly elongated and the extensional viscosity becomes an inportant parameter in estimating properties during and after the process....

  11. Characterization of polymers by bubble inflation, Jens H. Christensen, Henrik K. Rasmussen, Erik M. Kjær and Carsten L. Lauridsen

    DEFF Research Database (Denmark)

    Rasmussen, Henrik Koblitz; Christensen, Jens H.; Kjær, Erik Michael

    1999-01-01

    is modelled using a finite element method in 3D Cartesian coordinates. The K-BKZ constitutive quation is used to model the non-linear properties of the material. Using linear viscoelastic properties from oscillative shear measurements and measurements of the bubble inflation, estimetion of the strain......In order to characterize materials using a simple and relative inexpensive method, the bubble inflation technique was modified. A polymer plate is clamped between a Teflon coated plate and a heated cylinder. By applying air through the heating plate the polymer membrane deforms into the cylinder....... The top position of the membrane is monitored by fiberoptic sensors positioned in the cylinder. The pressure difference across the membrane is measured as well. The deformation in this inflation device is non-uniform and is only biaxial in the top of the deformed membrane. Due to this, the responce...

  12. CROSSWORK for Glycans: Glycan Identificatin Through Mass Spectrometry and Bioinformatics. / Rasmussen, Morten ; Thaysen-Andersen, Morten ; Højrup, Peter. 2009

    DEFF Research Database (Denmark)

    Rasmussen, Morten

    Chemical cross-linking is a useful method for deriving information on protein structure and protein-protein interaction. We have developed a method combining chemical cross-linking with mass-spectrometry and bioinformatics (CrossWork) to automate search and validation of cross-links in large...

  13. Clinical course and variability of non-Rasmussen, nonstroke motor and sensory epilepsia partialis continua: a European survey and analysis of 65 cases

    DEFF Research Database (Denmark)

    Mameniskiene, Ruta; Bast, Thomas; Bentes, Carla

    2011-01-01

    To gain new insights into the clinical presentation, causes, treatment and prognosis of epilepsia partialis continua (EPC), and to develop hypotheses to be tested in a prospective investigation.......To gain new insights into the clinical presentation, causes, treatment and prognosis of epilepsia partialis continua (EPC), and to develop hypotheses to be tested in a prospective investigation....

  14. Rumsansning mellem vane og oplevelse

    DEFF Research Database (Denmark)

    Reeh, Henrik

    2004-01-01

    Walter Benjamin, Steen Eiler Rasmussen, arkitektur, sansning, vane, taktilitet, oplevelse, erfaring, Rom......Walter Benjamin, Steen Eiler Rasmussen, arkitektur, sansning, vane, taktilitet, oplevelse, erfaring, Rom...

  15. Growth of non-axisymmetric disturbances of the free surface in the filament stretching rheometer: experiments and simulation. Bach, A.; Rasmussen, H.K.; Longin, P.-Y.; Hassager, O

    DEFF Research Database (Denmark)

    Rasmussen, Henrik Koblitz; Bach, Anders; Longin, Pierre-Yves

    2002-01-01

    A filament stretching rheometer has been equipped with a bottom plate with a number of equally distributed perturbations of the circular rim. The temporal development of the resulting disturbance of the meniscus is followed with video recording and with simulations. At high strain rates the surfa...

  16. Experimental Investigation of the End Plate Instability in the Extension of Polymer Melts in a Filament Stretch Rheometer. P.-Y. Longin, H. K. Rasmussen, A. Bach and O. Hassager

    DEFF Research Database (Denmark)

    Rasmussen, Henrik Koblitz; Longin, Pierre-Yves; Bach, Anders

    2001-01-01

    We consider here a particular instability, an axis symmetry breaking meniscus instability, that occurs under certain conditions in the transient filament stretching apparatus near the endplates as the plates are separated. Spiegelberg and McKinley [1] investigated this instability development in ...

  17. Monitoring Protein Conformation Changes as an Activating Step for Protein Interactions with Cross-linking/MS Analysis. / Chen, Zhuo; Rasmussen, Morten; Tahir, Salman; Clark, C.A.C; Barlow, Paul; Rappsilber, Juri

    DEFF Research Database (Denmark)

    Rasmussen, Morten

    -linked peptides have been enriched with SCX-StageTips. High resolution MS/MS spectra were acquired on an LTQ-Orbitrap mass spectrometer coupled online to a nanoHPLC. Singly and doubly charged ions were rejected for fragmentation. Peak lists were generated with MaxQuant. The database searches for cross......, the cross-link data and the crystal structure can be harmonized. We suggest that cross-linking can capture aspects of protein dynamics in solution that are not observable in static crystal structures....

  18. En fascinerende fortælling om det 20. århundredes musik

    DEFF Research Database (Denmark)

    Bonde, Lars Ole

    2011-01-01

    Anmeldelse af Karl Aage Rasmussen: Musik i det tyvende århundrede: En fortælling. Gyldendal 2011.......Anmeldelse af Karl Aage Rasmussen: Musik i det tyvende århundrede: En fortælling. Gyldendal 2011....

  19. Külas on NATO peasekretär

    Index Scriptorium Estoniae

    2012-01-01

    Balti riikides visiidil olev NATO peasekretär Anders Fogh Rasmussen külastas NATO küberkaitsekeskust ja tunnustas Eesti panust kaitseorganisatsiooni kübervõimekusse. Rasmussen pidas ka avaliku loengu Tallinna Ülikoolis

  20. Key issues for mountain areas

    National Research Council Canada - National Science Library

    Price, Martin F; Jansky, Libor; Iatsenia, Andrei A

    2004-01-01

    ... and livelihood opportunities . . . ... Safdar Parvez and Stephen F. Rasmussen 86 6 Mountain tourism and the conservation of biological and cultural diversity... Wendy Brewer Lama and Nikhat Sattar 11...

  1. Rootsi suursaadik tänas eestlasi kaastunde eest / Dag Hartelius ; interv. Andri Maimets

    Index Scriptorium Estoniae

    Hartelius, Dag

    2003-01-01

    Intervjuu Rootsi suursaadikuga Eestis Dag Harteliusega mõrvatud Rootsi välisministrist Anna Lindhist ja poliitikute turvalisuse tagamisest. Kommenteerivad: Anders Fogh Rasmussen, Kristiina Ojuland, Igor Ivanov

  2. Cellular therapies in trauma and critical care medicine: Looking towards the future.

    Directory of Open Access Journals (Sweden)

    Shibani Pati

    2017-07-01

    Full Text Available Shibani Pati and Todd Rasmussen summarize progress in preclinical research on cellular therapeutics for traumatic injury and its sequelae and discuss prospects for clinical translation.

  3. Berta Wasbutzki: Erindringer om Herman Bang

    DEFF Research Database (Denmark)

    Heede, Dag

    2014-01-01

    Oversættelse fra tysk af erindringer om Herman Bang fra Berlin 1907-1907 med introduktion, tekst og annotering. Oversættelse foretaget af Sten Rasmussen......Oversættelse fra tysk af erindringer om Herman Bang fra Berlin 1907-1907 med introduktion, tekst og annotering. Oversættelse foretaget af Sten Rasmussen...

  4. Critical Exchange: Peculiar Bedfellows--Gender, Sexuality, Religion and Schooling: A Reply to Stern

    Science.gov (United States)

    Rasmussen, Mary L.

    2017-01-01

    Mary L. Rasmussen is a sociologist of education with expertise in studies of gender and sexuality. This angle of scrutiny (Harwood 2006) is her point of departure in conversations about schooling and religion. From this angle, Rasmussen believes that schooling and religion can be incredibly powerful in creating community. She is also clear that…

  5. Enhydrina schistosa

    DEFF Research Database (Denmark)

    Redsted Rasmussen, Arne; Sanders, Kate L.; Lobo, Aaron

    2010-01-01

    Rasmussen, A., Sanders, K., Lobo, A. & Courtney, T. 2010. Enhydrina schistosa. In: IUCN 2013. IUCN Red List of Threatened Species. Version 2013.2. . Downloaded on 02 January 2014.......Rasmussen, A., Sanders, K., Lobo, A. & Courtney, T. 2010. Enhydrina schistosa. In: IUCN 2013. IUCN Red List of Threatened Species. Version 2013.2. . Downloaded on 02 January 2014....

  6. Hydrophis atriceps

    DEFF Research Database (Denmark)

    Redsted Rasmussen, Arne; Lobo, Aaron; Sanders, Kate L.

    2010-01-01

    Rasmussen, A., Lobo, A., Sanders, K. & Guinea, M. 2010. Hydrophis atriceps. In: IUCN 2013. IUCN Red List of Threatened Species. Version 2013.2. . Downloaded on 02 January 2014.......Rasmussen, A., Lobo, A., Sanders, K. & Guinea, M. 2010. Hydrophis atriceps. In: IUCN 2013. IUCN Red List of Threatened Species. Version 2013.2. . Downloaded on 02 January 2014....

  7. Når kroppen flyder

    DEFF Research Database (Denmark)

    Rösing, Lilian Munk

    2013-01-01

    Rasmussen en grænsefigur; vi er i et univers hvor huden på én gang er under dannelse og opløsning. Kropsligheden hos Rasmussen indkredses dels med psykoanalytiske begreber om hud-jeg og abjektion, dels med Roland Barthes’ begreb om det metamentale. Afslutningsvis perspektiveres der til to andre eksempler i...

  8. Nuclear translocation contributes to regulation of DNA excision repair activities

    DEFF Research Database (Denmark)

    Knudsen, Nina Østergaard; Andersen, Sofie Dabros; Lützen, Anne

    2009-01-01

    .T. Tomicic, W.P. Roos, B. Kaina, Mechanisms of human DNA repair: an update, Toxicology 193 (2003) 3-34; N.B. Larsen, M. Rasmussen, L.J. Rasmussen, Nuclear and mitochondrial DNA repair: similar pathways? Mitochondrion 5 (2005) 89-108]. Protein interactions are not only important for function, but also...

  9. Is an Inuit Literary History Possible?

    Science.gov (United States)

    Martin, Keavy

    2010-01-01

    In 1921, the Greenlandic anthropologist Knud Rasmussen set out to travel twenty thousand miles by dog team across Inuit Nunaat--the Inuit homeland. During this three-year journey--the famous Fifth Thule Expedition--Rasmussen was struck by the similarities in the language and culture of Inuit communities across the entire Arctic. Considering the…

  10. Den urbane dimension

    DEFF Research Database (Denmark)

    Reeh, Henrik

    bykultur, filosofi, idehistorie, byplanlægning, kunst, George Simmel, Sigfried Kracauer, Walther Benjamin, Paul Virilio, Pierre Alekchinsky, Steen Eiler Rasmussen, Arne Gaardmand......bykultur, filosofi, idehistorie, byplanlægning, kunst, George Simmel, Sigfried Kracauer, Walther Benjamin, Paul Virilio, Pierre Alekchinsky, Steen Eiler Rasmussen, Arne Gaardmand...

  11. Learning-based Nonlinear Model Predictive Control to Improve Vision-based Mobile Robot Path Tracking

    Science.gov (United States)

    2015-07-01

    as ‘support points’ (Quiñonero- Candela and Rasmussen, 2005). An alternative are Local GP (LGP) methods, as implemented in this work, which enable...247. Quiñonero- Candela , J. and Rasmussen, C. E. (2005). A Unifying View of Sparse Approximate Gaussian Process Regression. The Journal of Machine

  12. Influence of Cold Exposure on Ventilation, Respiratory Heat Loss, and Pulmonary Deposition/Clearance

    Science.gov (United States)

    1990-06-25

    AFR 190-1 Distribution Unlimited ERNEST A. HAYGOOD, Ist Lt, USAF Executive Officer, Civilian Institution Programs 13. ABSTRACT (Maximum 200 words) DTIC...the unanesthetized dog. Am. i. Physiol. 213:547-556, 1967. 46. Hemingway , A., T. Rasmussen, H. Wikoff and A.T. Rasmussen. Effects of heating

  13. A new subgenus of Heterotrigona from New Guinea (Hymenoptera: Apidae)

    DEFF Research Database (Denmark)

    Engel, Michael S.; Rasmussen, Claus

    2017-01-01

    A new subgenus is established within the Indomalayan stingless bee genus Heterotrigona Schwarz (Meliponini). Sahulotrigona Engel & Rasmussen, new subgenus, is distinguished from amongst other Heterotrigona, particularly the subgenus Platytrigona Moure, within which one of the two included species...

  14. NATO juht: Eestile otsest ohtu pole

    Index Scriptorium Estoniae

    2014-01-01

    NATO peasekretär Anders Fogh Rasmussen ütles pressikonverentsil, et kuna Eesti on NATO liige, siis otsest agressiooniohtu Eestile praegu ei ole, kuid siiski on väga tähtis kollektiivkaitse tugevdamine

  15. In vivo activities of Baicalin against Chlamydia trachomatis

    African Journals Online (AJOL)

    USER

    2010-03-15

    Rasmussen et al., 1997). The infectivity of the chlamydia was expressed as the number of inclusion forming units. Baicalin (HPLC Content > 98.0%) from Chongqing Green Valley. Bio-tech Co. LTD. (Chongqing, China).

  16. Disease: H01812 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available chronic neurological disorder, characterised by unilateral inflammation of the cerebral cortex, drug-resistant epilepsy... for Rasmussen's encephalitis but are also present in epilepsy patients with severe, early onset disease and

  17. NATO chief arrives to discuss alliance's new strategy / Ella Karapetyan

    Index Scriptorium Estoniae

    Karapetyan, Ella

    2009-01-01

    8. oktoobril Eestis visiidil viibinud NATO peasekretär Anders Fogh Rasmussen kohtus president Toomas Hendrik Ilvese ja välisminister Urmas Paetiga. Teemadeks oli Afganistanis toimuv, NATO ja viimase suhted Venemaaga

  18. Robottens Anatomi

    DEFF Research Database (Denmark)

    Nørgaard, Bent

    2009-01-01

    Videnskabsteater om robotter med bl.a Baard Owe, Steen Rasmussen, Musik :Hans Sydow, Scenografi: Cathia Hauberg Engel, Visuals: Anders Boe/Mikkel Larris, Koncept: Mikael Valeur, Willie Flint, Mimo Antabi, Bent Nørgaard...

  19. International conference "Cultural Plurality in Estonia : Policies and Solutions"

    Index Scriptorium Estoniae

    2000-01-01

    Ettekandjad: Katrin Saks, Mall Hellam, Mati Luik, Kirsti Häkkinen, Vello Pettai, Ivi Proos, Katri Raik, NiinaOrhimenko, Ib Ostergaard Rasmussen, Urve Läänemets, Jüri Valge, Aleksander Dusman, Raivo Juurak, Rein Ruutsoo

  20. Study Gives Good Odds on Nuclear Reactor Safety

    Science.gov (United States)

    Russell, Cristine

    1974-01-01

    Summarized is data from a recent study on nuclear reactor safety completed by Norman C. Rasmussen and others. Non-nuclear events are about 10,000 times more likely to produce large accidents than nuclear plants. (RH)

  1. CARDIOVASCULAR DISORDERS AMONG PERSONS WITH DOWN SYNDROME

    NARCIS (Netherlands)

    Vis, Jeroen C.; van Engelen, Klaartje; Bouma, Berto J.; Bilardo, Catia M.; Blom, Nico A.; Mulder, Barbara J. M.

    2010-01-01

    Down syndrome is the most common chromosomal abnormality among liveborn infants and is the most frequent chromosomal cause of intellectual disability (Frid, Drott, Lundell, Rasmussen, & Anneren, 1999). It is a multisystem disorder, characterized by various congenital defects, organic disorders,

  2. Identification of Behavioral Indicators in Political Protest Music

    Science.gov (United States)

    2015-12-01

    Cecilia Rasmussen, “Closing of Club Ignited ‘Sunset Strip Riots,’” Los Angeles Times, August 5, 2007, http://articles.latimes.com/2007/aug/05/local/me...Songwriter: James Henry Miller Song: Bring The Boys Home Performer: Freda Payne Songwriters: Angelo Bond, General Johnson, Greg Perry Song...Conflict. Westport, CT: Greenwood Press, 2001. Rasmussen, Cecilia , “Closing of Club Ignited ‘Sunset Strip Riots,’” Los Angeles Times. August 5, 2007. http

  3. Before Smith’s Mill: Archaeological and Geological Investigations, Smithville Lake, Missouri. Volume 1. Text.

    Science.gov (United States)

    1982-06-01

    Falkenburg, Gene Jenkins, Lee Rasmussen, Leonard Bates, Ruth Myers, Arlene Smith, Theresa Baber, Karen Summers, Brad Bailey. Project Photographer: James...artifacts, distributional etudies), Gerald Lang (ceramics, geographic background, mapping), Lee RAsmussen (flotation processing), Karen Summners...where bedrock might cause nickpoints could be made using the struc- tural contour map and gas well logs reported by McQueen and Greene (1938: 144, 145

  4. Sådan lyver man om krige

    DEFF Research Database (Denmark)

    Holtermann, Jakob v. H.

    2013-01-01

    Anders Fogh Rasmussen lykkedes med det, som amerikanske George W. Bush og britiske Tony Blair ikke kunne: at slippe politisk uskadt ud af Irak, skriver filosof. Tre simple trin gjorde det muligt for Fogh at lyve sig uskadt ud af Irakkrigen.......Anders Fogh Rasmussen lykkedes med det, som amerikanske George W. Bush og britiske Tony Blair ikke kunne: at slippe politisk uskadt ud af Irak, skriver filosof. Tre simple trin gjorde det muligt for Fogh at lyve sig uskadt ud af Irakkrigen....

  5. The Falklands War: Understanding the Power of Context in Shaping Argentine Strategic Decisions

    Science.gov (United States)

    2007-09-01

    York: Macmillan, 1984). 73 Edward B. Zellem , "Clausewitz and Seapower: Lessons of the Falkland Islands War" (Ph.D. diss., Air Command and Staff...74 Zellem . 75 Thatcher, 228. 76 Anderson, 31. 77 Arquilla and Rasmussen, 764. 78 Hastings and Jenkins, 75...Freedman and Gamba-Stonehouse, 147. 79 Arquilla and Rasmussen, 764. 80 Zellem , 30. 81 Selected Extracts from Conflicto Malvinas: Official

  6. Øvelse gør mester

    DEFF Research Database (Denmark)

    Ryde, M.V.

    2002-01-01

    For de forskere der arbejder med vindmøller, er det lidt af et kulturskift at man nu skal tænke i patenter frem for at udveksle alle erfaringer direkte med industrien. Flemming Rasmussen har taget konsekvensen og ligefrem "øvet" sig på at patentere.......For de forskere der arbejder med vindmøller, er det lidt af et kulturskift at man nu skal tænke i patenter frem for at udveksle alle erfaringer direkte med industrien. Flemming Rasmussen har taget konsekvensen og ligefrem "øvet" sig på at patentere....

  7. Development of C-lignin with G/S-lignin and lipids in orchid seed coats – an unexpected diversity exposed by ATR-FT-IR spectroscopy

    DEFF Research Database (Denmark)

    Barsberg, Søren Talbro; Lee, Y-I; Rasmussen, Hanne Nina

    2018-01-01

    Cite this article: Barsberg ST, Lee Y-I, Rasmussen HN. Development of C-lignin with G/S-lignin and lipids in orchid seed coats – an unexpected diversity exposed by ATR-FT-IR spectroscopy. Seed Science Research https:// doi.org/10.1017/S0960258517000344......Cite this article: Barsberg ST, Lee Y-I, Rasmussen HN. Development of C-lignin with G/S-lignin and lipids in orchid seed coats – an unexpected diversity exposed by ATR-FT-IR spectroscopy. Seed Science Research https:// doi.org/10.1017/S0960258517000344...

  8. Hydraulic Evaluation of the LEANCON Wave Energy Converter

    DEFF Research Database (Denmark)

    Kofoed, Jens Peter; Frigaard, Peter

    This report is a product of the co-operation agreement between Aalborg University and LEANCON (by Kurt Due Rasmussen) on the evaluation and development of the LEANCON wave energy converter (WEC). The work reported here has focused on evaluation of the power production of the device, based...... on laboratory testing of a model of the WEC provided by LEANCON. LEANCON, represented by Kurt Due Rasmussen, has been heavily involved in the testing of the device, including the instrumentation, model setup and execution of the tests in the laboratory, all under the supervision of the personnel of the Wave...... Energy Research Group at Department of Civil Engineering, Aalborg University....

  9. Atomistic simulations of screw dislocation cross slip in copper and nickel

    DEFF Research Database (Denmark)

    Vegge, Tejs

    2001-01-01

    This paper presents calculations of screw dislocation cross slip in copper and nickel systems, using the nudged elastic band method and interatomic potentials based on the effective-medium theory. The validity of recent attempts to predict cross slip activation energies by ‘elastic scaling’ between...... fcc metals is investigated, finding that reasonable predictions can be made using the approach suggested by Rasmussen [T. Rasmussen, Phil. Mag. A 80 (2000) 1291]. The experimentally determined cross slip activation energy and the minimum stable screw dislocation dipole height for copper are explained...

  10. Heart rate and heart rate variability in dogs with different degrees of myxomatous mitral valve disease

    DEFF Research Database (Denmark)

    Rasmussen, Caroline Elisabeth; Falk, Bo Torkel; Zois, Nora Elisabeth

    2011-01-01

    HEART RATE AND HEART RATE VARIABILITY IN DOGS WITH DIFFERENT DEGREES OF MYXOMATOUS MITRAL VALVE DISEASE. CE Rasmussen1, T Falk1, NE Zois1, SG Moesgaard1, HD Pedersen2, J Häggström3 and LH Olsen1. 1. Department of Basic Animal and Veterinary Sciences, Faculty of Life Sciences, University of Copenh......HEART RATE AND HEART RATE VARIABILITY IN DOGS WITH DIFFERENT DEGREES OF MYXOMATOUS MITRAL VALVE DISEASE. CE Rasmussen1, T Falk1, NE Zois1, SG Moesgaard1, HD Pedersen2, J Häggström3 and LH Olsen1. 1. Department of Basic Animal and Veterinary Sciences, Faculty of Life Sciences, University...

  11. Supporting productive thinking: The semiotic context for Cognitive Systems Engineering (CSE).

    Science.gov (United States)

    Flach, John

    2017-03-01

    The central thesis of this paper is that Rasmussen framed his approach to Cognitive Systems Engineering from the perspective of a Triadic Semiotic Model. This frame became the context for integrating multiple intellectual threads including Control Theory, Information Theory, Ecological Psychology, and Gestalt Psychology into a coherent theoretical framework. The case is made that the triadic semiotic framework is essential for a complete appreciation of the constructs that were central to Rasmussen's approach: Abstraction Hierarchy, Skill-Rules-Knowledge Model, Ecological Interface Design, and Proactive Risk Management. Copyright © 2015 Elsevier Ltd. All rights reserved.

  12. Supervisory Control of Multiple Uninhabited Systems - Methodologies and Enabling Human-Robot Interface Technologies (Commande et surveillance de multiples systemes sans pilote - Methodologies et technologies habilitantes d’interfaces homme-machine)

    Science.gov (United States)

    2012-12-01

    spectrum of operational missions. • Semiotic engineering of man-machine interface in order to adapt displays and commands. • New modalities of man...control task. Ergonomics, Vol. 42, No. 3, pp. 462-492, 1999. [21] Rasmussen, J., Skills, Rules, and Knowledge; Signals, Signs , and Symbols, and other

  13. Characterization of Contaminant Migration Potential Through In-Place Sediment Caps

    Science.gov (United States)

    2011-06-01

    organics in sand caps. Apatite and organoclay have the broadest range of effectiveness for metals (Viana, P.Z. et al. 2008), while activated carbon...coke (Zimmerman et al. 2004; 7    Murphy, P., et al. 2006), peat (Rasmussen, G. et al. 2002), and organoclays (Viana, P.Z., et al. 2008) are being

  14. Turkey’s Rising Influence and Increasing Political Boldness: Implications for Its Relationship with NATO

    Science.gov (United States)

    2017-03-31

    The controversy began when a Danish newspaper published multiple cartoons depicting the prophet Mohammed as a terrorist. Rasmussen, who was the Danish...originals/2015/09/turkey-syria-usa-ankara- dream -to-set- up-three-cities.html (accessed September 21, 2016). 9 Humeyra Pamuk and Umit Bektas, “Turkey Fires

  15. Social mening og viden på sociale video sites

    DEFF Research Database (Denmark)

    Rasmussen, Tove Arendt

    2011-01-01

    også producent og distributør adf viden i de sociale mediers brugerfællesskaber. Brugeren er ikke kun ’user’, men ’produser’ (sammentrækning af user og producer), skriver den amerikanske medieforsker Axel Bruns, som både Tove Arendt Rasmussen og hans Jørn Nielsen citerer i deres artikler”....

  16. Spatial distribution of atmospheric carbon monoxide over Bay of ...

    Indian Academy of Sciences (India)

    gases and Radiation Budget (ICARB)' for a two-month pre-monsoon period in 2006 with the ocean segment covering Bay of Bengal and Arabian ... and intercontinental transport of pollution (Khalil and Rasmussen 1994; Khalil 1995; ... air over the ocean surface was measured continu- ously using an IR analyser, Monitor ...

  17. Multimodal pain management after arthroscopic surgery

    DEFF Research Database (Denmark)

    Rasmussen, Sten

    Multimodal Pain Management after Arthroscopic Surgery By Sten Rasmussen, M.D. The thesis is based on four randomized controlled trials. The main hypothesis was that multimodal pain treatment provides faster recovery after arthroscopic surgery. NSAID was tested against placebo after knee arthroscopy...

  18. Prediction of mineral scale formation in geothermal and oilfield operations using the Extended UNIQUAC model - Part II. Carbonate-scaling minerals

    DEFF Research Database (Denmark)

    Villafafila, Ada; Thomsen, Kaj; Stenby, Erling Halfdan

    2006-01-01

    Two additional parameters to account for the pressure dependency of solubility are added to the Extended UNIQUAC model presented by Thomsen and Rasmussen (1999). The improved model has been used for correlation and prediction of vapor-liquid-solid equilibrium for different carbonate systems (CaCO...

  19. Studies on relative catalytic efficiencies of zinc and aluminium on ...

    Indian Academy of Sciences (India)

    TECS

    2004; Fecht and Johnson 2004). Several experimental techniques for extending the range of observable under- cooling are available (Turnbull 1950a; Turnbull and Cech. 1950; Wang and Smith 1950; Duwez et al 1960; Fehling and Scheil 1962; Shiraishi and Wood 1964; Rasmussen and Loper Jr. 1975; Southin and ...

  20. To thine own self be true: self-fusion in single-celled tubes.

    Science.gov (United States)

    Hardin, Jeff

    2008-04-01

    In this issue of Developmental Cell, Rasmussen et al. (2008) investigate the morphogenesis of the Caenorhabditis elegans pharynx. Their results highlight the usefulness of this system for investigating the molecular mechanisms behind the unusual cell behaviors that underlie the formation of single-celled tubes during animal development.

  1. Astrocyte loss and astrogliosis in neuroinflammatory disorders

    NARCIS (Netherlands)

    Hostenbach, Stephanie; Cambron, Melissa; D'haeseleer, Miguel; Kooijman, Ron; De Keyser, Jacques

    2014-01-01

    Neuroinflammation can lead to either damage of astrocytes or astrogliosis. Astrocyte loss may be caused by cytotoxic T cells as seen in Rasmussen encephalitis, auto-antibodies such as in neuromyelitis optica (aquaporin-4 antibodies), or cytokines such as TNF-alpha in major depressive disorder.

  2. Comparative Effects of Circuit Training Programme on Speed and ...

    African Journals Online (AJOL)

    cce

    not become sufficiently stabilized (Stuart and Prugh, 1974). They also reported that the average ... illness, and other environmental factors (Stuart and Prugh, 1974). Bailey, Malina and Rasmussen (1978) stated that physical ..... and Exercise Science 5th Edition. Madison, Wisconsin: WCB Brown And Benchmark. Publishers.

  3. Elevers læring gennem undersøgelse og faglig læsning

    DEFF Research Database (Denmark)

    Negendahl, Kim; Daugbjerg, Peer

    2014-01-01

    Med afsæt i Prof. Jens Rasmussens (2013) argumenter for undervisningsdifferentiering vha. præstationsstandarder behandles differentiering af naturfagsundervisnings målsætning for alle skolens elever. Fokus vil være på læreres arbejde med undervisningsplaner og opstillede mål i forhold til undervi...

  4. Beyond Borders: Youth, Education, Sexuality, Desire

    Science.gov (United States)

    Mizzi, Robert

    2008-01-01

    This review examines two texts that relate to youth, sexuality, and education. The first is James Sears' "Youth, Education and Sexualities: An International Encyclopedia" (2005) and the second is "Youth and Sexualities: Pleasure, Subversion and Insubordination In and Out of Schools" (2004) edited by Mary Louise Rasmussen, Eric Rofes, and Susan…

  5. Expanding Your Coverage of Neuroscience: An Interview with Michael Gazzaniga

    Science.gov (United States)

    Rasmussen, Erin B.

    2006-01-01

    Erin Rasmussen is an Assistant Professor in the Department of Psychology at Idaho State University where she teaches learning, behavioral pharmacology, senior seminar, and introductory psychology. She received her MS and PhD in experimental psychology (with a minor in behavioral pharmacology and toxicology) from Auburn University. She taught at…

  6. NATO peasekretär tuleb Eestisse

    Index Scriptorium Estoniae

    2014-01-01

    Sel nädalal tuleb Eestisse kahepäevasele visiidile NATO peasekretär Anders Fogh Rasmussen, kohtumistel Eesti juhtidega on kõne all muutunud julgeolekuolukord Euroopas. Reedel peab ta Tallinna Ülikoolis avaliku loengu ning külastab koos välisministriga Ämari lennubaasi

  7. Pulmonary Artery Aneurysm as a Cause of Massive Hemoptysis: Diagnosis and Management

    Directory of Open Access Journals (Sweden)

    Peter Corr

    2011-01-01

    Full Text Available Massive hemoptysis is a life-threatening medical emergency. Prompt radiological diagnosis and management are essential. I present a case of an inflammatory pulmonary aneurysm (Rasmussen aneurysm from active pulmonary tuberculosis. This is an uncommon cause for massive hemoptysis which was successfully treated by endovascular coiling.

  8. Influence of clove oil on certain quorum-sensing-regulated functions ...

    Indian Academy of Sciences (India)

    2013-11-06

    Nov 6, 2013 ... MSc Thesis, Aligarh Muslim University, Aligarh, India. Skindersoe ME, Alhede M, Phipps R, Yang L, Jensen PO,. Rasmussen TB, Bjarnsholt T, Tolke-Nielsen T, Høiby N and. Givskov M 2008 Effects of antibiotics on quorum sensing in. Pseudomonas aeruginosa. Antimicrob. Agents Chemother. 52. 648– ...

  9. Answering without answering

    DEFF Research Database (Denmark)

    Gabrielsen, Jonas; Pontoppidan, Christina; Jønch-Clausen, Heidi

    2017-01-01

    its critical aspect with a more favorable one. Guided by classical rhetoric, the authors unfold the underlying logic of a shift. Analyzing 14 press conferences held by the Danish Prime Minister, Lars Løkke Rasmussen, they identify three subcategories of shifting: shift in time, shift of agent...

  10. Identity and Fear of Success.

    Science.gov (United States)

    Larkin, Linda

    1987-01-01

    Investigated the relation between ego identity and fear of success using the Rasmussen Ego Identity Scale (EIS), the Marcia interview for identity status, the Cohen People Knowing Questionnaire (PKO) to measure fear of success, and an occupational behavior and attitude questionnaire. EIS and PKO scores correlated significantly with each other and…

  11. Sensing, Navigation and Reasoning Technologies for the DARPA Urban Challenge

    Science.gov (United States)

    2007-12-31

    planning stack was reorganized to streamline the pro - cessing of information and minimize the number of internal states of the planner. The probabilistic...Oreman, Kenny Oslund, Robbie Paolini, Jimmy Paulos, Humberto Pereira, Rich Petras, Sam Pfister, Christopher Rasmussen, Bob Rasumussen, Dominic Rizzo

  12. Gene flow from Sorghum bicolor to its weedy relatives and its ...

    African Journals Online (AJOL)

    computer user

    2015-02-18

    Feb 18, 2015 ... methods for quantification of pollen-mediated gene flow from GM to conventional maize in a field study. Transgenic Res. 15:219-228. Ririe KM, Rasmussen RP, Wittwer CT (1997). Product differentiation by analysis of DNA melting curves during the polymerase chain reaction. Anal. Biochem. 245:154-60.

  13. Environment Debate

    African Journals Online (AJOL)

    komla

    savanna, marshes and grassland' (Ministry of Lands and Forestry, 2001) in describing the northern savanna area of Ghana. Also, in the south of the country ...... Deforestation and Climate Change in Selva Lacandona of Chiapas, Mexico: Some preliminary results. Norsk geogr. Tidsskr. 49(3): 105–122. Rasmussen K., Fog B.

  14. The effect of dietary lipid saturation and antioxidant source on the ...

    African Journals Online (AJOL)

    uvp

    2013-06-02

    Jun 2, 2013 ... The influence of a synthetic or natural antioxidant and lipid saturation on the apparent digestibility of ... digestibility of NDF seems to be higher when a natural antioxidant was included in the diet. The .... When ruminant feed is supplemented with lipid rich in UFA, methane emission is reduced (Rasmussen &.

  15. Ion and Electron Interactions at Thermal and Suprathermal Energies

    Science.gov (United States)

    1989-09-30

    RASMUSSEN Contract Manager Branch Chief FOR THE COMMANDER ROBERT A. SKRIVANEK Division Director This report has been reviewed by the ESD Public Affairs...than that in the present OH product vibrational distnbution. source (which is < 10 ’ TofT) when "pure helium" is used. 66 In addition, the present soune

  16. Inhibition of coagulation factors by recombinant barley serpin BSZx

    DEFF Research Database (Denmark)

    Dahl, Søren Weis; Rasmussen, S.K.; Petersen, L..C.

    1996-01-01

    Barley serpin BSZx is a potent inhibitor of trypsin and chymotrypsin at overlapping reactive sites (Dahl, S.W., Rasmussen, S.K. and Hejgaard, J. (1996) J. Biol, Chem., in press), We have now investigated the interactions of BSZx with a range of serine proteinases from human plasma, pancreas and l...

  17. To publish or not to publish: a systems analysis of longitudinal trends in publishing strategies of a human factors research organization

    NARCIS (Netherlands)

    Schraagen, Johannes Martinus Cornelis

    2013-01-01

    The goal of this study is to extend Rasmussen's framework for risk management to research organisations having to deal with reduced income from government funding and increased market orientation. One human factors research organisation was studied in detail. Using archival records, changes were

  18. Aging, longevity and health

    DEFF Research Database (Denmark)

    Rasmussen, Lene Juel; Sander, Miriam; Wewer, Ulla M.

    2011-01-01

    Session included speeches by Ralf Hemmingsen, Ulla Wewer, and Lene Juel Rasmussen and Keynote Addresses by four world renowned aging researchers: Povl Riis (The Age Forum), Bernard Jeune (University of Southern Denmark), George Martin (University of Washington, USA) and Jan Vijg (Albert Einstein School...

  19. Use of Negative-Pressure Wound Therapy in Orthopaedic Trauma

    Science.gov (United States)

    2012-09-01

    adequate débridement, anti- biotic therapy, degree of soft-tissue and bone injury, nutritional support, and baseline patient health status. Combat...VAC) therapy: Worse or worth? J Plast Reconstr Aesthet Surg 2009;62(5):675- 683. 13. Leininger BE, Rasmussen TE, Smith DL, Jenkins DH, Coppola C

  20. Analog domain adaptive equalizer for low power 40 Gbps DP-QPSK ...

    Indian Academy of Sciences (India)

    Sun H, Wu K and Roberts K 2008 Real-Time Measurements of a 40 Gb/s Coherent System. Opt. Express. 16(2): 873–879. Zhang G, Nelson L E, Pan Y, Birk M, Skolnick C, Rasmussen C, Givehchi M, Mikkelsen B, Scherer T,. Downs T and Keil W 2012 3760 km, 100G SSMF Transmission over Commercial Terrestrial DWDM.

  1. Euroopa majanduste andunud vikatimees Lars Christensen / Piret Reiljan

    Index Scriptorium Estoniae

    Reiljan, Piret, 1983-

    2007-01-01

    Danske Banki vanemanalüütik Lars Christensen on kahtluse alla seadnud Eesti valuutakomitee süsteemi püsimise. Vt. samas: Lars Christensen; Valik Lars Christenseni tänavusi hävitavaid hinnanguid Euroopa murelastele; Islandile kuulutatud häving kukutas otsemaid aktsiaid ja valuutat. Kommenteerivad Lars Rasmussen, Flemming Christensen ja Hanna Strandgaard

  2. What does it mean to say that a hegemonic project is neo-liberal?

    DEFF Research Database (Denmark)

    Hansen, Allan Dreyer

    Udgangspunktet for dette papir er VK-O regeringerne under Anders Fogh Rasmussen i nullerne i Danmark for at rejse spørgsmålet om hvilke teoretiske resurser Laclau og Mouffes hegemoni teori tilbyder, men også hvor yderlig udvikling og nye teoretiske artikulationer er nødvendig. Papiret giver ikke ...

  3. An Experimental Study of Fiberglass Composites Containing Metal Wire Joints

    Science.gov (United States)

    2009-09-01

    you to Erik Rasmussen, Scott Bartlett, Doug Loup , and Tim Dapp from the Naval Surface Warfare Center Carderock Division (NSWCCD) team for “Advanced...Monterey, California 4. Research Assistant Professor Jarema M. Naval Postgraduate School Monterey, California 5. Douglas C. Loup Naval Surface

  4. Study of Load Transfer and Fracture on Composite-to-Metal-Wire Joints

    Science.gov (United States)

    2009-03-01

    Mark F. Boseman March 2009 Thesis Advisor: Young W. Kwon Second Reader: Douglas C. Loup Approved for public release; distribution is...POSTGRADUATE SCHOOL March 2009 Author: Mark F. Boseman Approved by: Young W. Kwon Thesis Advisor Douglas C. Loup Second...Douglas C. Loup Naval Surface Warfare Center, Carderock Division West Bethesda, Maryland 5. Erik A. Rasmussen Naval Surface Warfare Center

  5. 76 FR 27320 - Granting of Request for Early Termination of the Waiting Period Under the Premerger Notification...

    Science.gov (United States)

    2011-05-11

    .... 04/14/2011 20110666 G James River Coal Company; International Resource Partners LP; James River Coal... the waiting period provided by law and the premerger notification rules. The listing for each.... Rasmussen; Sidney B. DeBoer 20110689 G International Petroleum Investment Company; Compania Espanola de...

  6. Danija võshlet imamov-podzhigatelei / Sergei Tushin

    Index Scriptorium Estoniae

    Tushin, Sergei

    2006-01-01

    Taani peaminister Anders Fogh Rasmussen selgitas kohtumisel Taani akrediteeritud suursaadikutega, et ajakirjandusvabadus on Taanis kaitstud seadusega, seepärast ei saa võimud sekkuda väljaannete sisusse. Samas väljendas ta kahetsust, et ebaõnnestunud nali Taani ajalehes on riivanud miljonite inimeste tundeid

  7. In vivo activities of Baicalin against Chlamydia trachomatis

    African Journals Online (AJOL)

    USER

    2010-03-15

    Mar 15, 2010 ... Fitoterapia, 80: 448-452. Laga M, Diallo MO, Buve, A (1994) Interrelationship of STD and HIV: where are we now? AIDS, Suppl. pp. 119-124. Rasmussen SJ, Eckmann L, Quayle AJ, Shen L, Zhang YX, Anderson. DJ (1997). Secretion of proinflammatory cytokines by epithelial cells in response to Chlamydia ...

  8. Ledelse via dårlig samvittighed

    DEFF Research Database (Denmark)

    Holm, Claus

    2009-01-01

    Statsminister Anders Fogh Rasmussen roser ikke sine ministre nok. Det vækker forargelse. Men selvstændighedens styrke er, at den viser sig ved, at folk indfrier forventninger uden at være akkompagneret af en leders klapsalver....

  9. Antibodies to voltage-gated potassium and calcium channels in epilepsy.

    NARCIS (Netherlands)

    Majoie, H.J.; Baets, M.H.V. de; Renier, W.O.; Lang, B.; Vincent, A.

    2006-01-01

    OBJECTIVE: To determine the prevalence of antibodies to ion channels in patients with long standing epilepsy. BACKGROUND: Although the CNS is thought to be protected from circulating antibodies by the blood brain barrier, glutamate receptor antibodies have been reported in Rasmussen's encephalitis,

  10. Diandric triploidy in a liveborn infant with 3-4 syndactyly and a ...

    African Journals Online (AJOL)

    chromosomal triploidy: correlation with parental origin of the extra haploid set. Am J Med Genet 1991;38(4):535-538. https://doi.org/10.1002/ajmg.1320380407. 5. Joergensen MW, Niemann I, Rasmussen AA, et al. Triploid pregnancies: genetic and clinical features of 158 cases. Am J Obstet Gynecol 2014;211(4):370 e1-19.

  11. Here and Elsewhere

    DEFF Research Database (Denmark)

    Bolt, Mikkel

    2014-01-01

    Mikkel Bolt Rasmussen argues that we must both continue to identify the revolutionary perspective as a communist one and continue to describe the revolution as a communist revolution. He contributes to the on-going discussion of the revolutionary position by reflecting on the relationship between...

  12. Development and Psychometric Evaluation of the Yale-Brown Obsessive-Compulsive Scale--Second Edition

    Science.gov (United States)

    Storch, Eric A.; Rasmussen, Steven A.; Price, Lawrence H.; Larson, Michael J.; Murphy, Tanya K.; Goodman, Wayne K.

    2010-01-01

    The Yale-Brown Obsessive-Compulsive Scale (Y-BOCS; Goodman, Price, Rasmussen, Mazure, Delgado, et al., 1989) is acknowledged as the gold standard measure of obsessive-compulsive disorder (OCD) symptom severity. A number of areas where the Y-BOCS may benefit from revision have emerged in past psychometric studies of the Severity Scale and Symptom…

  13. Polar Lows Over the Northeast Greenland Sea

    Science.gov (United States)

    1991-12-01

    Danmarks Havn in North East Greenland near 77 N. However, as pointed out by Rasmussen L (1989) the climate in this region is extremely cold, and katabatic...Satellite images. Satel ite images from 16th Novembe~r 1987 when the polar low was best developed show such a "katabatic signiature’ .1 the Danmarks

  14. Tule 13. juunil valima! : Toomas Hendrik Ilves

    Index Scriptorium Estoniae

    2004-01-01

    Ilmunud ka: SL Õhtuleht, 8. juuni 2004, lk. 8-9. Euroopa Parlamendi kandidaadi kohta avaldavad arvamust Eesti avaliku elu tegelased ja mitmete riikide poliitikud: Göran Persson, Ulpu Iivari, Gary Titley, Poul Nyrup Rasmussen, Peeter Kreitzberg jt.

  15. NATO juht: liikmete kaitse on meie põhitöö / Evelyn Kaldoja

    Index Scriptorium Estoniae

    Kaldoja, Evelyn, 1980-

    2009-01-01

    NATO peasekretär Anders Fogh Rasmussen külastas Eestit ja andis koos president Toomas Hendrik Ilvesega 8. oktoobril 2009 Kadriorus pressikonverentsi. NATO peasekretär rõhutas, et alliansi eksisteerimise põhjuseks on läbi aegade olnud ja jääb oma liikmete kaitse

  16. ejesm.v10i3.2

    African Journals Online (AJOL)

    USER

    2017-04-04

    Apr 4, 2017 ... global Positioning system was used to measure the Longitude and Latitude of the sampling locations ..... probably be due to intrusion from the external surroundings as a result of high traffic movement that ... The detection of Zn in higher levels in zone 3 is in agreement with the findings of Rasmussen et al.

  17. 'A ‘stain on the […] otherwise good reputation of Denmark'

    DEFF Research Database (Denmark)

    Villadsen, Lisa Storm

    of the Nazi occupation of Denmark – with particular focus on a web site created for school children. Further, the speech is read up against a second speech held the day after in which Fogh Rasmussen addressed some of the public criticism launched against the nature of the collective memory promoted...

  18. Treatment Failure for Malaria in Vietnam

    Centers for Disease Control (CDC) Podcasts

    2017-06-05

    WHO malaria expert, Dr. Charlotte Rasmussen, discusses anti-malarial drug resistance in Vietnam.  Created: 6/5/2017 by National Center for Emerging and Zoonotic Infectious Diseases (NCEZID).   Date Released: 6/5/2017.

  19. Evaluation of a four month rehabilitation program for stroke patients with balance problems and binocular visual dysfunction

    DEFF Research Database (Denmark)

    Schow, Trine; Harris, Paul; Teasdale, Thomas William

    2016-01-01

    Trine Schow, Paul Harris, Thomas William Teasdale, Morten Arendt Rasmussen. Evaluation of a four month rehabilitation program for stroke patients with balance problems and binocular visual dysfunction. NeuroRehabilitation. 2016 Apr 6;38(4):331-41. doi: 10.3233/NRE-161324....

  20. Producing a local, organic diet gives a healthy, sustainable and more climate-friendly diet

    DEFF Research Database (Denmark)

    Mogensen, Lisbeth; Kristensen, Troels; Hermansen, John Erik

    2011-01-01

    In: Organic is life – Knowledge for tomorrow (Neuhoff, D., Halberg, N., Rasmussen. I., Hermansen, J., Ssekyewa, C., Sohn, S.M. eds.). Proceedings of the Third Scientific Conference of the International Society of Organic Agriculture Research (ISOFAR), held at the 17th IFOAM Organic World Congress...

  1. African Journal of AIDS Research - Vol 12, No 1 (2013)

    African Journals Online (AJOL)

    Barriers and facilitators to antiretroviral therapy adherence among patients with HIV in Bissau, Guinea-Bissau: A qualitative study · EMAIL FULL TEXT EMAIL FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Dlama N Rasmussen, David da Silva Té, Lotte Rodkjaer, Inés Oliveira, Candida Medina, Toke ...

  2. Generation of recombinant pestiviruses using a full-genome amplification strategy

    DEFF Research Database (Denmark)

    Rasmussen, Thomas Bruun; Reimann, I.; Uttenthal, Åse

    2010-01-01

    Complete genome amplification of viral RNA provides a new tool for the generation of modified viruses. We have recently reported a full-genome amplification strategy for recovery of pestiviruses (Rasmussen et al., 2008). A full-length cDNA amplicon corresponding to the Border disease virus-Gifhor...

  3. Uncertainty in Steady-State Diagnostics of a Current-Pressure Transducer: How Confident are We in Diagnosing Faults

    Science.gov (United States)

    2014-10-02

    though the hyperparameters may have estimated previously. For details of this method, refer to (Rasmussen, 2004; Chiles & Delfiner , 1999). Once the...non-Gaussian Bayesian tracking. IEEE Transactions on Signal Processing, 50(2), 174–188. Chiles, J., & Delfiner , P. (1999). Geostatistics: modeling

  4. 24-HOUR ELECTROCARDIOGRAPHY IN CLINICAL HEALTHY CAVALIER KING CHARLES SPANIELS, WIRE-HAIRED DACHSHUNDS AND CAIRN TERRIERS

    DEFF Research Database (Denmark)

    Rasmussen, Caroline Elisabeth; Vesterholm, Stina; Ludvigsen, Trine Pagh

    2010-01-01

    24-HOUR ELECTROCARDIOGRAPHY IN CLINICAL HEALTHY CAVALIER KING CHARLES SPANIELS, WIRE-HAIRED DACHSHUNDS AND CAIRN TERRIERS. CE Rasmussen1, S Vesterholm1, TP Ludvigsen1, SG Moesgaard1, HD Pedersen2, J Häggström3, LH Olsen1. 1. Department of Basic Animal and Veterinary Sciences, Faculty of Life...

  5. Mechanisms Mediating the Perception of Complex Acoustic Patterns

    Science.gov (United States)

    1988-09-26

    Deutsch . Member of panel (chaired by William A. Yost) preparing report on "Classification of Complex Sounds" for the Committee on Hearing, Bioacoustics...processes: a literature review. Archiv fUr Psychologie , 130, 161-211. [18] Rasmussen, G. L. (1955): Descending or "feed-back" connections of the auditory

  6. Comparison of conventional culture and real-time quantitative PCR ...

    African Journals Online (AJOL)

    2009-10-28

    Oct 28, 2009 ... mechanism of transmission (Yu, 1993; Steinert et al., 1997). Legionellosis is generally considered to ... fluorescence change rate over time as a function of temperature for each sample), which can be used .... estimated by means of the slope calculation method from a calibration dilution curve (Rasmussen, ...

  7. 76 FR 71835 - Energy Conservation Program: Energy Conservation Standards for Direct Heating Equipment

    Science.gov (United States)

    2011-11-18

    ..., due to ambiguity in the gathered data for vented gas log sets indentified by stakeholders at the... provide heat. (Small Business Administration (SBA), No. 96 at p. 2; Big Woods, No. 3 at p. 1; Lennox... p. 1; Rasmussen, No. 208 at p. 1; Golden Blount, No. 210 at p. 1; Independence Marketing, No. 214 at...

  8. Preparation of Fine Oxide Powders by Emulsion Precipitation.

    Science.gov (United States)

    1987-05-31

    enough at 230 0C that water vapor was not effectively removed from the reactor in a static air atmosphere, and it condensed back into the oil bath...53 -- 4--.. V ’ ’- -*.1i-. VAK ."Y ’ i 7. REFERENCES 1. M. D. Rasmussen, G. W. Jordan, M. Akinc, 0. Hunter, Jr. and M. F. Berard, "Influence of

  9. An Exploratory Simulator Study on the Use of Active Control Devices in Car Driving

    Science.gov (United States)

    1992-05-04

    action (pp. 167-201). Berlin: Springer-Verlag. Rasmussen, J. (1986). Information processing and Human-Machine Interaction. An Approach to Cognitive ...1981). Schnittstellen in Mensch-Maschine-Systemen. In H. Schmidtke (Hrsg.), Lehrbuch der Ergonomie (2. Aufl.) (S. 351-376). Mfinchen: Hanser. Rutley

  10. Foghs forslag. Sammenhæng mellem tale, identitet og strategi

    Directory of Open Access Journals (Sweden)

    Mie Femø Nielsen

    2008-09-01

    Full Text Available Hvor fintunet kan selvfremstillingen være i moderne politikeres fremtræden på tv? Hvordan kan man overhovedet arbejde analytisk med personlig fremtræden? Denne artikel diskuterer identitetsarbejde ud fra konversationsanalytiske begreber med henblik på at give et bud på, hvordan man kan analysere og diskutere et fænomen som ‘profil’. Der eksemplificeres med et uddrag af en tv-duel fra folketingsvalget 2001 mellem Anders Fogh Rasmussen (daværende formand for Venstre og leder af oppositionen og Poul Nyrup Rasmussen (daværende statsminister og formand for Socialdemokratiet, og det vises, hvordan Fogh formåede at fremstå som ‘konstruktiv opponent’, hvilket korresponderede med Venstres valgslogan, “Tid til forandring”.

  11. Human characteristics and limits from human error in aviation; Kokuki no hyuman era kara mita Ningen no tokusei to genkai

    Energy Technology Data Exchange (ETDEWEB)

    Kuroda, I. [Waseda Univ., Tokyo (Japan)

    1996-08-10

    Aircraft accidents must be examined from 5 viewpoints, man, machine, media, mission, and management. Errors and mistakes are incongruent phenomena occurring at the interface between man and environment or between man and machine. The problems of human factor in man-machine system are grouped into physiological, physical, pathological, pharmacological, psychological, and social psychological factors. The difference of the human cognitive property from that of the computer is the presence of control system which gives big effects on the information processing system. In other words, it is the presence of discord of the function of two types of brains. The SRK model, i.e. Rasmussen`s simplified model, divides human behavior into 3 steps of mastery, rule, and knowledge bases. Impatience, personal honor, royalty, high participative sense to organization, pride, exhaustion, monotony, tediousness, anger, and the state of emergency are the factors for the conditions which cause errors in human activity. 2 refs., 1 fig.

  12. Global health intervention from North to South: (Academic) preparation of students

    DEFF Research Database (Denmark)

    Singla, Rashmi; Rasmussen, Louise Mubanda

    2018-01-01

    Global health intervention from North to South: (Academic) preparation of students By Rashmi Singla & Louise Mubanda Rasmussen, Roskilde University, Denmark This chapter discusses how to conduct before- intervention preparation of students based on a pioneer course collaboration between the subje......Global health intervention from North to South: (Academic) preparation of students By Rashmi Singla & Louise Mubanda Rasmussen, Roskilde University, Denmark This chapter discusses how to conduct before- intervention preparation of students based on a pioneer course collaboration between......’ interactive participation is central to opening up a space where issues of power and identity in the encounter of global health interventions can be critically examined and reflected upon. We conclude the chapter by critically discussing the potential of analytic generalisation from the experience of running...

  13. Comparison of Outcomes of Operatively Treated Bicondylar Tibial Plateau Fractures by External Fixation and Internal Fixation

    Directory of Open Access Journals (Sweden)

    CC Chan

    2012-03-01

    Full Text Available The outcome of bicondylar tibial plateau fractures treated with either external fixation (35 patients or internal fixation (24 patients was reviewed. Outcome measures included the Rasmussen score, clinical complications, development of osteoarthritis and the requirement for total knee replacement (TKR. Twenty-two (92% anatomical reductions were achieved in the internal fixation group compared to 27 (77% in the external fixation group. Infective complications were more common in the external fixation group (9 patients, 26% due to pin tract infection. There were no deep infections in the internal fixation group. The mean Rasmussen score was not significantly different (mean score 32 in external fixation and 29 in internal fixation between the two groups and the incidence of osteoarthritis was the same in both groups. Four patients in the external fixation group underwent a TKR compared to 5 patients in the internal fixation group. Bicondylar tibial plateau fractures have similar outcomes following external or internal fixation.

  14. What kind of knowledge do small companies need to improve their working environment?

    DEFF Research Database (Denmark)

    Antonsson, Ann-Beth; Hasle, Peter

    2015-01-01

    for risk assessment or risk management. However, there is a lot of criticism towards this kind of good practice, ranging from that it can easily be used for behavioural control to the problem with odd working environments and the need for tailoring the solutions to each workplace. The pros and cons...... of knowledge from a small company perspective. Discussion There are several different ways of describing knowledge. From a working environment point of view, knowledge can be divided into knowledge about risks, risk assessment and control measures. Control measures can in turn be divided into knowledge about...... the concrete control measures and the management routines needed in the company. Another kind of analytical framework has been presented by Rasmussen, who divides knowledge into skill-based, rule-based and knowledge-based behaviour. Rasmussen describes that skill-based knowledge is the automated knowledge...

  15. Joint Global War on Terror (GWOT) Vascular Injury Study 2

    Science.gov (United States)

    2017-02-01

    AWARD NUMBER: W81XWH-13-2-0014 TITLE: Joint Global War on Terror (GWOT) Vascular Injury Study 2 PRINCIPAL INVESTIGATOR: MAJ Zachary...6. AUTHOR(S) Zachary M. Arthurs, MD, Chief of Vascular Surgery 5d. PROJECT NUMBER MAJ , US Armyzachary.m.arthurs.mil@mail.mil 5e. TASK NUMBER...stations and he is now at Fort Detrick in Combat Casualty Care. MAJ Zachary Arthurs was selected to be the incoming PI of this effort by Col Rasmussen

  16. Prediction of Mineral Scale Formation in Geothermal and Oilfield Operations using the Extended UNIQUAC Model. Part I: Sulphate Scaling Minerals

    DEFF Research Database (Denmark)

    Garcia, Ada V.; Thomsen, Kaj; Stenby, Erling Halfdan

    2005-01-01

    Pressure parameters are added to the Extended UNIQUAC model presented by Thomsen and Rasmussen (1999). The improved model has been used for correlation and prediction of solid-liquid equilibrium (SLE) of scaling minerals (CaSO4, CaSO4·2H2O, BaSO4 and SrSO4) at temperatures up to 300°C and pressur...

  17. Generalized Boolean Functions as Combiners

    Science.gov (United States)

    2017-06-01

    public release. Distribution is unlimited. 12b. DISTRIBUTION CODE 13. ABSTRACT (maximum 200 words) In this digital age , cryptography has formed the...Craig Rasmussen Chair, Department of Applied Mathematics iii THIS PAGE INTENTIONALLY LEFT BLANK iv ABSTRACT In this digital age , cryptography has formed...Equation 2.2 is primitive. One of the consequences of having a primitive polynomial is that the period of the non-singular LFSR will be maximal for all

  18. Proceedings of the 2010 AFMS Medical Research Symposium. Volume 3. Enroute Track: Abstracts and Presentations

    Science.gov (United States)

    2011-03-15

    emerging threats for in-garrison or deployed operations. Topics of interest include research in bio-surveillance, infectious disease , emerging...nanomaterials, radiation, etc.), monitoring disease trends, other areas of preventive medicine, public and environmental health relevant to the military...Iraq and Afghanistan 59th Medical Wing (MDW)/SSSOGV Todd E. Rasmussen MD, Joseph M. White MD, W. Darrin Clouse MD Gabriel E. Burkhardt MD, Adam

  19. Multifocality as a prognostic factor in breast cancer patients registered in Danish Breast Cancer Cooperative Group (DBCG) 1996-2001

    DEFF Research Database (Denmark)

    Joergensen, L.E.; Gunnarsdottir, K.A.; Lanng, C.

    2008-01-01

    The purpose of this study was to investigate the prognostic influence of multifocality in breast cancer patients. In a cohort of 7196 patients there were 945 patients with multifocality. We found no prognostic influence of multifocality on overall survival when controlling for known prognostic......, Gunnarsdottir KA, Rasmussen BB, Moeller S, Lanng C. The prognostic influence of multifocality in breast cancer patients. Breast 2004;13:188-193]....

  20. Fair embedsmandslogik eller magtspil

    DEFF Research Database (Denmark)

    Michelsen, Knud

    2014-01-01

    I 1907, mens Knud Rasmussen er på sin såkaldte etnografiske ekspedition, fremsættes en række klager over hans optræden på rejser i Vestgrønland, især foranlediget af de daværende hunderegulativer og karantænebestemmelser. Klagerne samles i en skrivelse til indenrigsministeriet fra dav. inspektør ...

  1. Hvordan ser a-kassernes fremtid ud?

    DEFF Research Database (Denmark)

    Rasmussen, Stine

    2013-01-01

    Hvilken betydning har det haft for a-kasserne, at de i de seneste 10-15 år er blevet udsat for ændringer, nye krav og massiv kritik fra omgivelserne om hvorvidt de kan fungere på det moderne arbejdsmarked? De spørgsmål forsøger Stine Rasmussen at adressere i en artikel for a-kassernes brancheorga...

  2. Cellular injury and neuroinflammation in children with chronic intractable epilepsy

    OpenAIRE

    Rosenow Joshua; Kelley Kent; Laux Linda; DiPatri Arthur; Alden Tord D; Nordli Douglas R; Choi Jieun; Schuele Stephan U; Rajaram Veena; Koh Sookyong

    2009-01-01

    Abstract Objective To elucidate the presence and potential involvement of brain inflammation and cell death in neurological morbidity and intractable seizures in childhood epilepsy, we quantified cell death, astrocyte proliferation, microglial activation and cytokine release in brain tissue from patients who underwent epilepsy surgery. Methods Cortical tissue was collected from thirteen patients with intractable epilepsy due to focal cortical dysplasia (6), encephalomalacia (5), Rasmussen's e...

  3. Joint Global War on Terror (GWOT) Vascular Injury Study 2

    Science.gov (United States)

    2016-02-01

    changed duty stations and he is now at Fort Detrick in Combat Casualty Care. MAJ Zachary Arthurs was selected to be the incoming PI of this...principal discipline(s) of the project? Vascular injury represents a common cause of morbidity and mortality in not only wartime but also the civilian...Detrick in Combat Casualty Care. MAJ Zachary Arthurs was selected to be the incoming PI of this effort by Col Rasmussen and took leadership of the

  4. Er dansk læreruddannelse under internationalt niveau?

    DEFF Research Database (Denmark)

    Holm, Claus

    2010-01-01

    I Danmark snakker vi på 17. år om at undervisningsdifferentiere, men vi bruger ikke lærebøger i læreruddannelsen, der fortæller, hvordan det lader sig gøre i praksis. Professor Jens Rasmussen forklarer, hvorfor vi i Danmark ikke forener teori og praksis, mens lande som Singapore og Canada bare gør...

  5. A Naval Postgraduate Dental School Analysis Of Initial Endodontic Treatment

    Science.gov (United States)

    2015-07-01

    DENTAL SCHOOL ANALYSIS OF INITIAL ENDODONTIC TREATMENT ALLEN DANIEL RASMUSSEN D.M.D., ENDODONTICS, 2015 Thesis directed by: CAPT Teny Webb, D.D.S...re-treatment, surgical treatment, or canal obturation using Resilon, carrier-based, silver points or a paste fill technique . Additionally, if any...location by quadrant Follow-up variables Pain location by tooth Permanent restoration History of orthodontic treatment Intracanal post History of external

  6. Nutrients for the aging eye

    OpenAIRE

    Rasmussen HM; Johnson EJ

    2013-01-01

    Helen M Rasmussen,1 Elizabeth J Johnson2 1Educational Studies, Lesley University, Cambridge, MA, USA; 2Carotenoid and Health Laboratory, Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA Abstract: The incidence of age-related eye diseases is expected to rise with the aging of the population. Oxidation and inflammation are implicated in the etiology of these diseases. There is evidence that dietary antioxidants and anti-infla...

  7. Remote Medical Diagnosis System (RMDS) Design Review Meeting Minutes 27-28 August 1980, held at Department of the Navy, Washington, DC.

    Science.gov (United States)

    1981-08-01

    Head Bioacoustics & Bionics Division Biosciences Department 7’. i" i S+1 Iŕ UNCLASSIFIED SECURITY CLASSIFICATION OF THIS PAGE (When Data Entered) REPOT...Transmitted and Received Images (Analog and Digital) of Eye Over ADM Terminals Via HF...19 i1 Project Plan...21 12 EDM Procurement Cycle Summary...22...received images (analog and digital) of eye over ADM terminals via hf. *1 19 -14. ENGINEERING DEVELOPMENT MODELS (EDMs) Dr. W. Rasmussen (NOSC): Many

  8. Breastfeeding Initiation and Maintenance Among African Americans and Blacks Enrolled in a Nurse Home Visitation Program: An Outcomes Focused Program Evaluation

    Science.gov (United States)

    2013-12-11

    breastfeeding. Rasmussen found maternal obesity contributed to slower onset of lactogenesis 19 II (i.e., onset of copious milk secretion), which in tum, reduced...immediately after onset of lactogenesis II is critically important for milk production more so than it is later in lactation (187; 188; 220; 251...to reduce confounding. Epidemiology 16:247-53 187. Neville MC, Morton J. 2001. Physiology and endocrine changes underlying human lactogenesis IL The

  9. Advancing Best Practices for the Formulation of Localized Sea Level Rise/Coastal Inundation Extremes Scenarios for Military Installations in the Pacific Islands

    Science.gov (United States)

    2015-07-14

    value analysis discussed in this report. Embedded within an investigation framework (Figure 13), the guidance is grounded in the notion that for a...Validation is carried out subsequent to analysis. Activities such as ground -truthing and monitoring of indicators and impacts are identified to ensure...and New York, NY, USA, 1535 pp. Kopp, R. W., R. M. Horton, C. M. Little, J. X. Mitrovica, M. Oppenheimer, D. J. Rasmussen, B. H. Strauss , and C

  10. Two Troubling Trends in the Conversation Over Whether Clinical Ethics Consultants Have Ethics Expertise.

    Science.gov (United States)

    Brummett, Abram; Ostertag, Christopher J

    2017-04-18

    In a recent issue of the Journal of Medicine and Philosophy, several scholars wrote on the topic of ethics expertise in clinical ethics consultation. The articles in this issue exemplified what we consider to be two troubling trends in the quest to articulate a unique expertise for clinical ethicists. The first trend, exemplified in the work of Lisa Rasmussen, is an attempt to define a role for clinical ethicists that denies they have ethics expertise. Rasmussen cites the dependence of ethical expertise on irresolvable meta-ethical debates as the reason for this move. We argue against this deflationary strategy because it ends up smuggling in meta-ethical assumptions it claims to avoid. Specifically, we critique Rasmussen's distinction between the ethical and normative features of clinical ethics cases. The second trend, exemplified in the work of Dien Ho, also attempts to avoid meta-ethics. However, unlike Rasmussen, Ho tries to articulate a notion of ethics expertise that does not rely upon meta-ethics. Specifically, we critique Ho's attempts to explain how clinical ethicists can resolve moral disputes using what he calls the "Default Principle" and "arguments by parity." We show that these strategies do not work unless those with the moral disagreement already share certain meta-ethical assumptions. Ultimately, we argue that the two trends of (1) attempting to avoid meta-ethics by denying that clinical ethicists have ethics expertise, and (2) attempting to articulate how ethics expertise can be used to resolve disputes without meta-ethics both fail because they do not, in fact, avoid doing meta-ethics. We conclude that these trends detract from what clinical ethics consultation was founded to do and ought to still be doing-provide moral guidance, which requires ethics expertise, and engagement with meta-ethics. To speak of ethicists without ethics expertise leaves their role in the clinic dangerously unclear and unjustified.

  11. [The blindness in the literature-Jose Saramago: blindness and Albert Bang: the blind witness].

    Science.gov (United States)

    Permin, H; Norn, M

    2001-01-01

    Two novels with different aspects of blindness seen through the doctors eyes. The Portuguese Nobel-prize winner José Saramago's story of a city struck by an epidemic of "white blindness", where the truth is what we cannot bear to see. The Danish author and unskilled labourer Albert Bang's (synonym with Karl E. Rasmussen) crime novel describes a blind or pretend to be blind butcher, who is a witness to a murder. Both novels are lyric, thought-provoking and insightful.

  12. Security conference convenes in Munich / Ella Karapetyan

    Index Scriptorium Estoniae

    Karapetyan, Ella

    2011-01-01

    Eesti president osales Münchenis toimunud rahvusvahelisel julgeolekupoliitika konverentsil, kus räägiti ka strateegilist tuumarelvastust piiravast START lepingust, olukorrast araabia maades ja finantskriisi mõjust julgeolekule. Toomas Hendrik Ilves juhtis diskussiooni relvastuskontrollist. Konverentsil osalesid ka Robert Zoellick, Wolfgang Schaueble, George Soros, Karl-Theodor zu Guttenberg, William Hague, Hillary Clinton, Sergei Lavrov, David Cameron, Catherine Ashton, Ban ki-moon, Anders Fogh Rasmussen ja Angela Merkel. Müncheni julgeolekukonverents 04.02.2011 - 06.02.2011

  13. Turkey-U.S. Defense Cooperation: Prospects and Challenges

    Science.gov (United States)

    2011-04-08

    unsuccessful.34 Military’s Changing Role in Turkish Society Since the formative days of the Turkish republic under Mustafa Kemal Ataturk in the 1920s and...foundational secular republican principles established by Ataturk in the 1920s.36 The military’s preeminence within the Turkish government and society at...space.” Jorge Benitez, “Rasmussen fails to persuade Turkey to close Izmir base,” acus.org/natosource, April 7, 2011. 35 The Ataturk -led Turkish army

  14. Effektivitet af naturligt drevne radontiltag året rundt

    DEFF Research Database (Denmark)

    Haker Høegh, Britt; Rasmussen, Torben Valdbjørn

    Denne rapport omhandler projektet Effektivitet af naturligt drevne radontiltag året rundt. Projektet er et spireprojekt finansieret af Innovationsnetværket InnoBYG og Forsknings- og Innovationsstyrelsen. Projektet er gennemført af Teknologisk Institut i samarbejde med Statens Byggeforskningsinsti...... bygningsejerne, som har stillet deres bygninger til rådighed. Rapporten er udarbejdet af Britt Haker Høegh, Teknologisk Institut, og Torben Valdbjørn Rasmussen, SBi....

  15. Titanium Dioxide Nanoparticle Integrated Concrete: An Assessment of Nanoparticle Release When Exposed to UV Radiation and Wet Weather Conditions

    Science.gov (United States)

    2016-03-23

    These applications exploit titanium dioxide’s self-cleaning property to prevent the growth of organic material and abate air pollutants like...weatherization protocol for carbon 24 nanotubes developed by NanoRelease (32). This protocol is patterned after the ISO 4892-2/2013 standard...skin physiology 14:92 41. Ryman-Rasmussen JP, Tewksbury EW, Moss OR, Cesta MF, Wong BA, Bonner JC. 2009. Inhaled multiwalled carbon nanotubes

  16. Rumlig kultur / Spatial Culture

    DEFF Research Database (Denmark)

    Eiler Rasmussen, Siegfried Kracauer, Walter Benjamin og Michel de Certeau. Kulturvidenskabelige begreber og metoder aktiveres i analyser af kulturelle rum, for eksempel Daniel Libeskinds museer, mørket på Christiania, genopbygningen af Dresdens Frauenkirche og historierne bag Berlins Tempelhof...... artikler et forskningsfelt for rumlig kultur, hvori alskens sanse- og refleksionsformer finder sammen. Based in humanistic urban studies as practiced in the Department of Arts and Cultural Studies, University of Copenhagen, SPATIAL CULTURE outlines a novel framework for understanding the social...

  17. Sustainment and Advancement of Amputee Care

    Science.gov (United States)

    2015-04-08

    clinical efficacy of the BiOM®, a prosthetic ankle device designed to provide artificial muscle power that enables amputees to walk with reduced fatigue ...Epidemiological Catchment Area study. JAMA Psychiatry. January 8, 2014. 56. Seal KH, Metzler TJ, Gima KS, Bertenthal D, Maguen S, Marmar CR. Trends...Exceptional Rehabilitation (BADER) Consortium; 2014. 91. Rasmussen TE. No drift. JAMA Surgery. 2014:E1-E2. 92. Healey K. With 3-D printer, Creighton

  18. Stress and adaptation in beef heifers. 2. Influence

    African Journals Online (AJOL)

    (Baxter,1974);. (ii) adaptations in relation to behaviour (Rasmussen,. B a n k s , B e r r y & B e c k e r , 1 9 6 2 , B r y a n t , 1 9 7 0 ) ;. (iii) adaptations in relation to increased animal density which cause hypertrophy of the adrenals (Siegel,. 7959a; 1959b, 1960) or the occurence of gastric ulcers. (Selye, 1956; Kowalczyk, 1969);.

  19. Wave Induced Loads on the LEANCON Wave Energy Converter

    DEFF Research Database (Denmark)

    Frigaard, Peter; Kofoed, Jens Peter; Beserra, Eliab Ricarte

    This report is a product of the co-operation agreement between Aalborg University and LEANCON (by Kurt Due Rasmussen) on the evaluation and development of the LEANCON wave energy converter (WEC). The work reported here has focused on evaluation of the wave induced loads on the device, based...... in the laboratory, all under the supervision of the personnel of the Wave Energy Research Group at Department of Civil Engineering, Aalborg University....

  20. Venstres strategiske mediespil

    OpenAIRE

    Rasmussen, Karina Liv P.S.; Jørgensen, Trine Løfholm; Ekstrøm, Bjørn Kjerulff; Jensen, Pelle Dueholm

    2008-01-01

    In our project of Danish politics, we concentrate on the Danish political parties, and their change from ideological to strategically planning in relation to the Danish media in order to gain votes during the election process. We analyze potential consequences of this behaviour in the Danish society among the parties, with a focus on the Danish Liberal Party, Venstre, and the strategies which the Chairman and Primeminister Anders Fogh Rasmussen, express in his biography. With a theo...

  1. A Collaborative Research System for Functional Outcomes Following Wartime Extremity Vascular Injury

    Science.gov (United States)

    2012-01-01

    transtibial , or above the ankle, in the lower extremity and above the forearm in the upper extremity. Secondary amputations are defined as...Rasmussen, MD, Fort Sam Houston, Texas Vascular injury with hemorrhage and ischemia is a signifi-cant cause of battlefield morbidity (i.e., amputation ...this cohort, extremity vascular injuries are confirmed, and method of management (primary amputation , ligation, repair, etc.) was recorded. When

  2. Litteraturens brugspotentiale

    DEFF Research Database (Denmark)

    Rasmussen, Anders Juhl

    2017-01-01

    This article examines the relationship between the uses of literature and narrative medicine. Peter Seeberg’s short story “The Patient” is interpreted as an illness narrative in relation to Ludwig Wittgenstein’s therapeutic philosophy of language. Rasmussen suggests that Seeberg’s reliance...... on the use of everyday language in the short story is an analogy to a new position in literary studies where criticism and engagement, rationality and emotionality are united....

  3. On the Nature of Severe Orographic Thunderstorms near the Andes in Subtropical South America

    Science.gov (United States)

    Rasmussen, Kristen Lani Emi

    Identifying common features and differences between the mechanisms producing extreme convection near major mountain ranges of the world is an essential step toward a general understanding of orographic precipitation on a global scale. The overarching objective of this dissertation is to understand and examine orographic convective processes in general, while specifically focusing on systems in the lee of the Andes Mountains. Diagnosing the key ingredients necessary for generating high impact weather near extreme topography is crucial to our understanding of orographic precipitating systems. An investigation of the most intense storms in 11 years of TRMM Precipitation Radar (PR) data has shown a tendency for squall lines to initiate and develop east of the Andes with a mesoscale organization similar to storms in the U.S. Great Plains (Rasmussen and Houze 2011). In subtropical South America, however, the topographical influence on the convective initiation and maintenance of the mesoscale convective systems (MCSs) is unique. The Andes and other mountainous terrain of Argentina focus deep convective initiation in the foothills of western Argentina (Romatschke and Houze 2010; Rasmussen and Houze 2011). Subsequent to initiation, the convection often evolves into propagating MCSs similar to those seen over the U.S. Great Plains sometimes producing damaging tornadoes, hail and floods across a wide agricultural region (Rasmussen and Houze 2011; Rasmussen et al. 2014b). The TRMM satellite was designed to determine the spatial and temporal variation of tropical and subtropical rainfall amounts and storm structures around the globe with the goal of understanding the factors controlling the precipitation. However, the TRMM PR algorithm significantly underestimates surface rainfall in deep convection over land (Nesbitt et al. 2004; Iguchi et al. 2009; Kozu et al. 2009). When the algorithm rates are compared to a range of conventional Z-R relations, the rain bias tends to be

  4. Systems thinking applied to safety during manual handling tasks in the transport and storage industry.

    Science.gov (United States)

    Goode, Natassia; Salmon, Paul M; Lenné, Michael G; Hillard, Peter

    2014-07-01

    Injuries resulting from manual handling tasks represent an on-going problem for the transport and storage industry. This article describes an application of a systems theory-based approach, Rasmussen's (1997. Safety Science 27, 183), risk management framework, to the analysis of the factors influencing safety during manual handling activities in a freight handling organisation. Observations of manual handling activities, cognitive decision method interviews with workers (n=27) and interviews with managers (n=35) were used to gather information about three manual handling activities. Hierarchical task analysis and thematic analysis were used to identify potential risk factors and performance shaping factors across the levels of Rasmussen's framework. These different data sources were then integrated using Rasmussen's Accimap technique to provide an overall analysis of the factors influencing safety during manual handling activities in this context. The findings demonstrate how a systems theory-based approach can be applied to this domain, and suggest that policy-orientated, rather than worker-orientated, changes are required to prevent future manual handling injuries. Copyright © 2013 Elsevier Ltd. All rights reserved.

  5. Stress relaxation and reversed flow of low-density polyethylene melts following uniaxial extension

    DEFF Research Database (Denmark)

    Huang, Qian; Rasmussen, Henrik K.; Skov, Anne Ladegaard

    2012-01-01

    The extensional dynamics of two low-density polyethylene melts Lupolen 3020D and Lupolen 1840D, both showing a stress overshoot in start-up of uniaxial extension [Rasmussen, H. K., J. K. Nielsen, A. Bach, and O.Hassager, 'Viscosity overshoot in the start-up of uniaxial elongation of low density...... polyethylene melts,' J. Rheol. 49(2), 369-381 (2005)], have been further investigated in stress relaxation and reversed flow. After the overshoot, the stress relaxation has a remarkably faster decrease of the transient stress than when the relaxation is initiated before the overshoot. The measurements from...

  6. Análisis input-output de encadenamientos productivos y sectores clave en la economía mexicana

    OpenAIRE

    Fahd Boundi Chraki

    2016-01-01

    Este artículo busca identificar las industrias clave de la economía mexicana. Para este propósito, se aplican las siguientes metodologías basadas en el análisis input-output: a) el método Chenery-Watabane (1958) para el cálculo de encadenamientos productivos directos; b) el método Rasmussen (1963) para el cálculo de encadenamientos productivos totales; c) el enfoque de demanda de Leontief (1985) para cuantificar los encadenamientos hacia atrás directos y totales; d) el enfoque de oferta de Gh...

  7. THE EFFECTS OF POSSIBLE CONTAMINATION ON THE RADIOCARBON DATING OF THE DEAD SEA SCROLLS II: EMPIRICAL METHODS TO REMOVE CASTOR OIL AND SUGGESTIONS FOR REDATING

    OpenAIRE

    Rasmussen, Kaare Lund; van der Plicht, Johannes; Doudna, Gregory; Nielsen, Frederik; Hojrup, Peter; Stenby, Erling Halfdan; Pedersen, Carl Th; Højrup, Peter

    2009-01-01

    While kept at the Rockefeller Museum in East Jerusalem, many Dead Sea Scroll fragments were exposed to castor oil by the original team of editors in the course of cleaning the parchments. Castor oil must be regarded as a serious contaminant in relation to radiocarbon dating. If modern castor oil is present and is not removed prior to dating, the (14)C dates will be skewed artificially towards modern values. In Rasmussen et al. (2001), it was shown that the standard AAA pretreatment procedure ...

  8. Importância e encadeamento dos setores de produção e abate e processamento da cadeia suinícola em Minas Gerais

    Directory of Open Access Journals (Sweden)

    Marielce de Cássia Ribeiro Tosta

    2005-06-01

    Full Text Available O objetivo deste estudo foi determinar a importância e os encadeamentos dos setores de produção e abate e processamento da cadeia suinícola em Minas Gerais, nos anos de 1980 e 1995, por meio dos índices de Rasmussen-Hirschman, do campo de influência e do índice puro de ligação (GHS. De acordo com os resultados, ambos os setores analisados foram considerados setores-chave com base apenas no índice de Rasmussen-Hirschman e no campo de influência, ou seja, apresentaram maior relevância quando considerados os seus impactos na demanda final e os seus poderes de encadeamento na economia. Apesar de não terem sido considerados setores-chave pelo GHS, os setores de produção e abate e processamento apresentaram grande potencialidade de impactos para trás. Em face desses resultados e dado que esses setores continuaram aumentando a sua participação na economia de Minas Gerais nos anos subseqüentes a 1995, tem-se indicação de que estes devam ter prioridade na alocação de recursos e na estratégia de promoções industriais por meio de políticas estaduais.The main objective of this study was to establish the importance and the enchainment of the production sector and butchery/making up sector of pork chain in Minas Gerais, in the years of 1980 and 1995, applying the Rasmussen-Hirschman index, the influence field index and GHS index. The results showed that both sectors were considered key sectors only by the Rasmussen-Hirschman index and the influence field index, i.e., they presented greater importance when observed its impacts on the final demand and its power of enchainment in the economy. Despite not being considered key sectors by the GHS index, they presented great potential of backward impacts. This result, and the fact that the participation of these sectors had been increasing in the Minas Gerais economy since 1995, suggests that those sectors the state policy makers need to give priority in resources allocation and in the

  9. NATO suurendab kohalolu

    Index Scriptorium Estoniae

    2014-01-01

    Põhja-Atlandi nõukogu kiitis Brüsselis heaks ettepanekud heidutuse ja kaitse suurendamiseks Ida-Euroopas. NATO peasekretäri Anders Fogh Rasmusseni sõnul suurendatakse seoses süveneva kriisiga Ukrainas heidutust Balti riikides lähipäevil. "Meil hakkab olema rohkem lennukeid õhus, rohkem laevu merel ning suurem valmisoleks maal," ütles Anders Fogh Rasmussen. Näiteks hakkavad õhuruumi turvavad lennukid rohkem lendama üle Balti riikide, liitlaste laevad paigutatakse Balti merele

  10. Análise do setor de produção e processamento de café em Minas Gerais: uma abordagem matriz insumo-produto

    Directory of Open Access Journals (Sweden)

    Venússia Eliane dos Santos

    2009-06-01

    Full Text Available Objetiva-se, neste trabalho, analisar o setor de produção e de processamento do café na estrutura econômica de Minas Gerais, determinando sua importância e seus encadeamentos dentro da estrutura do Estado, mediante a utilização de matriz de insumo-produto. Para tanto, são utilizados os índices de ligação de Rasmussen-Hirschman, a abordagem do campo de influência, o índice puro de ligação (abordagem GHS e os multiplicadores regionais de produto, renda e emprego. Essas aplicações são complementares na identificação de setores-chave da economia. A matriz utilizada foi regionalizada e refere-se ao ano de 1995. Segundo os índices de ligações de Rasmussen-Hirschman e a análise do campo de influência, o setor de produção de café encontra-se acima da média da economia, apresentando maiores encadeamentos para trás e para frente. Já o setor de processamento de café possui forte poder de encadeamento apenas para trás. Pela análise dos multiplicadores, observou-se que o setor de produção do café apresentou os melhores resultados em termos de geração de produto e renda, enquanto a indústria de café, em termos de produto e emprego.The objective of this work is to analyze coffee production and processing in the economic structure of Minas Gerais, to determine its importance and its linkages to the structure of the State economy, by using input-output matrix. Therefore, it is determined linkages indexes of Rasmussen-Hirschman, boarding fields, pure linkage index (GHS and regional multipliers of product, income and employment. These applications are complementary to the identification of key sectors of the economy. The 1995 input-output matrix was used. Linkages indexes of Rasmussen-Hirschman and the analysis of the influence field pointed out that coffee production presents multiplying indicators above those of the economy, presenting higher backward and forward linkages. The coffee processing sector presents only

  11. Effects of global change on tropical ecosystems

    CSIR Research Space (South Africa)

    Scholes, RJ

    1997-09-01

    Full Text Available .L., Parton, W.J., Ojima, D.S., Lodge, D.J., 1991. Hurricane effects on soil organic matter dynamics and forest production in the Luquillo Experimental Forest, Puerto Rico: results of simulation modelling. Biotropica 23, 364..., Hawaii. Tellus 28, 538-551. Keller, M., Veldkamp, E., Weitz, A.M., Reiners, W.A., 1993. Effect of pasture age on soil trace-gas emissions from a deforested area of Costa Rico. Nature 365, 244246. Khalil, M.A.K., Rasmussen...

  12. Trastorno del desarrollo de la coodinación : programas de intervención a través de la música, la danza y la percusión corporal (método BAPNE)

    OpenAIRE

    Díaz Pérez, Ariadna

    2016-01-01

    El Trastorno del Desarrollo de la Coordinación (TDC) es una patología relativamente reciente que afecta aproximadamente a un 5-8% de la población infantil y tiene una prevalencia muy alta considerándose como una enfermedad crónica (Camden, Wilson, Kirby y Missiuna, 2014; Cantell, Smyth y Ahonen, 2003; Rasmussen y Gillberg, 2000). Afecta a niños que no presentan ningún déficit cognitivo aparente pero que muestran un desarrollo motor deficiente para su edad, con limitaciones de coordinación y d...

  13. The Military's Business

    DEFF Research Database (Denmark)

    Rasmussen, Mikkel Vedby

    If the military were a business, would you buy shares? Over recent years, Western armed forces, particularly the US, have been costing more yet achieving less. At the same time, austerity measures are reducing defence budgets. This book uses defence data to examine the workings of modern Western...... militaries and explore what kind of strategies can overcome this gap between input and output. Instead of focusing on military strategy, Mikkel Vedby Rasmussen seeks to draw on the ideas of business strategy to assess alternative business cases - reforming military HR to combat instability in the 'Global...

  14. A Review of "Challenging Situations When Administering Palliative 
Chemotherapy--A Nursing Perspective".

    Science.gov (United States)

    Houlihan, Nancy G

    2015-05-01

    The December 2014 issue of the European Journal of Oncology Nursing published an article by Näppä, Rasmussen, Axelsson, and Lindqvist that reported on a qualitative study of the challenges experienced by Swedish nurses when administering palliative cancer treatment at the end of life. The study identified the various clinical scenarios that create dilemmas among nurses. The authors described why chemotherapy at the end of life has become so prevalent and offered strategies to minimize or prevent the moral distress that can occur. Research from the United States identified similar trends in end-of-life treatment and supportive recommendations for multidisciplinary palliative care team collaboration as a solution.

  15. Designing Urban Bikescapes

    DEFF Research Database (Denmark)

    Marling, Gitte

    2014-01-01

    This article presents analyses of the ‘Nørrebro Bike Route’ as an ‘urban bikescape’ consisting of a mixture of lanes and coupled urban places and small parks. It is a place to sit, to play and to relax, but at the same time it also a place for mobility. It is a social-technical assemblage (Urry 2...... (scale, rhythm, content) & aesthetics developed? (Thies- Evensen 1992, Venturi 1972, Rasmussen 2003, Thrift 2004, Merleau-Ponty 2009, Pallismaa 2005, Pink 2009)? Finally the article addresses the travelling ideas of ‘new urban bikescapes’ and Nordic urban space design....

  16. The Military's Business

    DEFF Research Database (Denmark)

    Rasmussen, Mikkel Vedby

    militaries and explore what kind of strategies can overcome this gap between input and output. Instead of focusing on military strategy, Mikkel Vedby Rasmussen seeks to draw on the ideas of business strategy to assess alternative business cases - reforming military HR to combat instability in the 'Global......If the military were a business, would you buy shares? Over recent years, Western armed forces, particularly the US, have been costing more yet achieving less. At the same time, austerity measures are reducing defence budgets. This book uses defence data to examine the workings of modern Western...

  17. Análisis input-output de encadenamientos productivos y sectores clave en la economía mexicana

    Directory of Open Access Journals (Sweden)

    Fahd Boundi Chraki

    2016-03-01

    Full Text Available This article seeks to identify the industrial sectors that are key to the Mexican economy. To this end the following methodologies are employed, all based on input-output analysis: a the Chenery Watabane Method (1958 for calculating direct productive linkages; b the Rasmussen Methods (1963 for calculating total productive linkages; c Leontief’s demand focus (1985 for the quantification of direct and total backward linkages; and d the supply focus of Ghosh (1958, 1968 used to quantify direct and total forward linkages. Finally the results of the application of these methods shows that the key sectors of Mexico’s economy are intermediate goods and capital goods.

  18. Defining Moments in MMWR History: Possible Association Between Zika Virus Infection and Microcephaly—Brazil, 2015 Los Angeles 1981

    Centers for Disease Control (CDC) Podcasts

    2018-01-11

    On January 22, 2016, MMWR first published a report on the possible association between Zika virus infection and microcephaly. This was the first of more than 60 MMWR reports on Zika virus. In this podcast, Dr. Sonja Rasmussen chats with Dr. Peggy Honein, co-lead for the Pregnancy and Birth Defects Task Force for CDC’s Zika response, about the mosquito-borne flavivirus.  Created: 1/11/2018 by MMWR.   Date Released: 1/11/2018.

  19. Formation of the N-Iodopyridinium Cation in an Alkane Environment

    DEFF Research Database (Denmark)

    Spanget-Larsen, Jens

    2006-01-01

    the apparent efficiency with which the pyI+ cation is formed in an apolar and aprotic medium like PE. With excess iodine, the peaks assigned to pyI+ dominate the observed mid-infrared spectrum. We suspect that a driving force for the ionic reaction is the formation of polyiodide anions in the channels...... of the polymer medium. Further investigation of the phenomenon is in progress. [1] H. S. van Deurs, M. L. M. Espersen, R. Nissen, M. H. Rasmussen, C. J. S. Schönbeck, Student Project, Roskilde University, June 2006 (in Danish)....

  20. Methane emissions from natural wetlands

    Energy Technology Data Exchange (ETDEWEB)

    Meyer, J.L. [Georgia Univ., Athens, GA (United States); Burke, R.A. Jr. [Environmental Protection Agency, Athens, GA (United States). Environmental Research Lab.

    1993-09-01

    Analyses of air trapped in polar ice cores in conjunction with recent atmospheric measurements, indicate that the atmospheric methane concentration increased by about 250% during the past two or three hundred years (Rasmussen and Khalil, 1984). Because methane is a potent ``greenhouse`` gas, the increasing concentrations are expected to contribute to global warning (Dickinson and Cicerone, 1986). The timing of the methane increase suggests that it is related to the rapid growth of the human population and associated industrialization and agricultural development. The specific causes of the atmospheric methane concentration increase are not well known, but may relate to either increases in methane sources, decreases in the strengths of the sinks, or both.

  1. Role Models on Dope

    DEFF Research Database (Denmark)

    Christiansen, Ask Vest; Gleaves, John

    2014-01-01

    Compared to football-players cyclists are virtuous role models. Yes, Lance Armstrong, Michael Rasmussen and other riders have doped, and because of this they have received the predicate as the most immoral athletes in the sporting world. But if morality is not only a question of whether a person...... has enhanced his or hers performances by the use of various drugs (and lied about it), but also is about human beings’ relations and interactions, then cycling isn’t as depraved as we like to tell each other. Football is much worse....

  2. Model-Based Integration and Interpretation of Data

    DEFF Research Database (Denmark)

    Petersen, Johannes

    2004-01-01

    Data integration and interpretation plays a crucial role in supervisory control. The paper defines a set of generic inference steps for the data integration and interpretation process based on a three-layer model of system representations. The three-layer model is used to clarify the combination...... of constraint and object-centered representations of the work domain throwing new light on the basic principles underlying the data integration and interpretation process of Rasmussen's abstraction hierarchy as well as other model-based approaches combining constraint and object-centered representations. Based...

  3. A Confession as Clear as Mud? Making Sense of Lance Armstrong’s Revelations

    DEFF Research Database (Denmark)

    Gleaves, John; Christiansen, Ask Vest

    2013-01-01

    Rabobank riders, e.g. Michael Rasmussen, doping scandals in American collegiate sport, a whole cluster of revelations from Australian elite sport and testimonies from the Operacion Puerto trial have added new information about closed doping practices. Moreover, it seems that the complex love......-hate relationship between sporting organizations and their anti-doping programs has pointed towards previously underexplored conflicts of interest. So while the past few months would leave any hungry doctoral student salivating over the wealth of new material, it is important to separate out what has become clearer...

  4. Born Global Sourcers – buying internationally right from the inception

    DEFF Research Database (Denmark)

    Rask, Morten; Servais, Per

    This article focuses on a particular type of international New Ventures (INV) the so-called Born Global Sourcers. Through the research development of the INV and by studying overview articles in the field it is concluded that nearly all research is centered on INV’s outward activities. At the same...... time researchers has identified various types of INV’s and based on the empirical work by Rasmussen et al (2010) a particular type of international new venture is isolated. The Born Global sourcers which is firms who conducts international purchasing from or near their establishment but who only...

  5. A Figure of Merit: Quantifying the Probability of a Nuclear Reactor Accident.

    Science.gov (United States)

    Wellock, Thomas R

    In recent decades, probabilistic risk assessment (PRA) has become an essential tool in risk analysis and management in many industries and government agencies. The origins of PRA date to the 1975 publication of the U.S. Nuclear Regulatory Commission's (NRC) Reactor Safety Study led by MIT professor Norman Rasmussen. The "Rasmussen Report" inspired considerable political and scholarly disputes over the motives behind it and the value of its methods and numerical estimates of risk. The Report's controversies have overshadowed the deeper technical origins of risk assessment. Nuclear experts had long sought to express risk in a "figure of merit" to verify the safety of weapons and, later, civilian reactors. By the 1970s, technical advances in PRA gave the methodology the potential to serve political ends, too. The Report, it was hoped, would prove nuclear power's safety to a growing chorus of critics. Subsequent attacks on the Report's methods and numerical estimates damaged the NRC's credibility. PRA's fortunes revived when the 1979 Three Mile Island accident demonstrated PRA's potential for improving the safety of nuclear power and other technical systems. Nevertheless, the Report's controversies endure in mistrust of PRA and its experts.

  6. Dermatomal Organization of SI Leg Representation in Humans: Revising the Somatosensory Homunculus.

    Science.gov (United States)

    Dietrich, Caroline; Blume, Kathrin R; Franz, Marcel; Huonker, Ralph; Carl, Maria; Preißler, Sandra; Hofmann, Gunther O; Miltner, Wolfgang H R; Weiss, Thomas

    2017-09-01

    Penfield and Rasmussen's homunculus is the valid map of the neural body representation of nearly each textbook of biology, physiology, and neuroscience. The somatosensory homunculus places the foot representation on the mesial surface of the postcentral gyrus followed by the representations of the lower leg and the thigh in superio-lateral direction. However, this strong homuncular organization contradicts the "dermatomal" organization of spinal nerves. We used somatosensory-evoked magnetic fields and source analysis to study the leg's neural representation in the primary somatosensory cortex (SI). We show that the representation of the back of the thigh is located inferior to the foot's representation in SI whereas the front of the thigh is located laterally to the foot's representation. This observation indicates that the localization of the leg in SI rather follows the dermatomal organization of spinal nerves than the typical map of neighboring body parts as depicted in Penfield and Rasmussen's illustration of the somatosensory homunculus. © The Author 2017. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  7. Elongational viscosity of monodisperse and bidisperse polystyrene melts

    DEFF Research Database (Denmark)

    Nielsen, Jens Kromann; Rasmussen, Henrik Koblitz; Hassager, Ole

    2005-01-01

    The startup and steady uniaxial elongational viscosity have been measured for two monodisperse polystyrene melts with molecular weights of 52 kg/mole (PS52K) and 103 kg/mole (PS103K), and for three bidisperse polystyrene melts. The bidisperse melts consist of PS103K or PS52K and a monodisperse...... (closed loop proportional regulator) using the laser in such a way that the stretch rate at the neck is kept constant. The rheometer has been described in more detail in (A. Bach, H.K. Rasmussen and O. Hassager, Journal of Rheology, 47 (2003) 429). PS390K show a decrease in the steady viscosity as a power......-law function of the elongational rate (A. Bach, K. Almdal, H.K. Rasmussen and O. Hassager, Macromolecules 36 (2003) 5174). PS52K and PS103K show that the steady viscosity has a maximum that is respectively 100% and 50% above 3 times the zero-shear-rate viscosity. The bidisperse melts show a significant...

  8. Aging, longevity and health

    Science.gov (United States)

    Rasmussen, Lene Juel; Sander, Miriam; Wewer, Ulla M.; Bohr, Vilhelm A.

    2016-01-01

    The IARU Congress on Aging, Longevity and Health, held on 5–7 October 2010 in Copenhagen, Denmark, was hosted by Rector Ralf Hemmingsen, University of Copenhagen and Dean Ulla Wewer, Faculty of Health Sciences, University of Copenhagen and was organized by Center for Healthy Aging (CEHA) under the leadership of CEHA Managing Director Lene Juel Rasmussen and Prof. Vilhelm Bohr, National Institute on Aging, NIH, Baltimore, USA (associated to CEHA). The Congress was attended by approximately 125 researchers interested in and/or conducting research on aging and aging-related topics. The opening Congress Session included speeches by Ralf Hemmingsen, Ulla Wewer, and Lene Juel Rasmussen and Keynote Addresses by four world renowned aging researchers: Povl Riis (The Age Forum), Bernard Jeune (University of Southern Denmark), George Martin (University of Washington, USA) and Jan Vijg (Albert Einstein School of Medicine, USA) as well as a lecture discussing the art-science interface by Thomas Söderqvist (Director, Medical Museion, University of Copenhagen). The topics of the first six Sessions of the Congress were: Neuroscience and DNA damage, Aging and Stress, Life Course, Environmental Factors and Neuroscience, Muscle and Life Span and Life Span and Mechanisms. Two additional Sessions highlighted ongoing research in the recently established Center for Healthy Aging at the University of Copenhagen. This report highlights outcomes of recent research on aging-related topics, as described at the IARU Congress on Aging, Longevity and Health. PMID:21820462

  9. Ending on a positive: Examining the role of safety leadership decisions, behaviours and actions in a safety critical situation.

    Science.gov (United States)

    Donovan, Sarah-Louise; Salmon, Paul M; Horberry, Timothy; Lenné, Michael G

    2018-01-01

    Safety leadership is an important factor in supporting safe performance in the workplace. The present case study examined the role of safety leadership during the Bingham Canyon Mine high-wall failure, a significant mining incident in which no fatalities or injuries were incurred. The Critical Decision Method (CDM) was used in conjunction with a self-reporting approach to examine safety leadership in terms of decisions, behaviours and actions that contributed to the incidents' safe outcome. Mapping the analysis onto Rasmussen's Risk Management Framework (Rasmussen, 1997), the findings demonstrate clear links between safety leadership decisions, and emergent behaviours and actions across the work system. Communication and engagement based decisions featured most prominently, and were linked to different leadership practices across the work system. Further, a core sub-set of CDM decision elements were linked to the open flow and exchange of information across the work system, which was critical to supporting the safe outcome. The findings provide practical implications for the development of safety leadership capability to support safety within the mining industry. Copyright © 2017 Elsevier Ltd. All rights reserved.

  10. Safety leadership and systems thinking: application and evaluation of a Risk Management Framework in the mining industry.

    Science.gov (United States)

    Donovan, Sarah-Louise; Salmon, Paul M; Lenné, Michael G; Horberry, Tim

    2017-10-01

    Safety leadership is an important factor in supporting safety in high-risk industries. This article contends that applying systems-thinking methods to examine safety leadership can support improved learning from incidents. A case study analysis was undertaken of a large-scale mining landslide incident in which no injuries or fatalities were incurred. A multi-method approach was adopted, in which the Critical Decision Method, Rasmussen's Risk Management Framework and Accimap method were applied to examine the safety leadership decisions and actions which enabled the safe outcome. The approach enabled Rasmussen's predictions regarding safety and performance to be examined in the safety leadership context, with findings demonstrating the distribution of safety leadership across leader and system levels, and the presence of vertical integration as key to supporting the successful safety outcome. In doing so, the findings also demonstrate the usefulness of applying systems-thinking methods to examine and learn from incidents in terms of what 'went right'. The implications, including future research directions, are discussed. Practitioner Summary: This paper presents a case study analysis, in which systems-thinking methods are applied to the examination of safety leadership decisions and actions during a large-scale mining landslide incident. The findings establish safety leadership as a systems phenomenon, and furthermore, demonstrate the usefulness of applying systems-thinking methods to learn from incidents in terms of what 'went right'. Implications, including future research directions, are discussed.

  11. Representing energy efficiency diagnosis strategies in cognitive work analysis.

    Science.gov (United States)

    Hilliard, Antony; Jamieson, Greg A

    2017-03-01

    This article describes challenges encountered in applying Jens Rasmussen's Cognitive Work Analysis (CWA) framework to the practice of energy efficiency Monitoring & Targeting (M&T). Eight theoretic issues encountered in the analysis are described with respect to Rasmussen's work and the modeling solutions we adopted. We grappled with how to usefully apply Work Domain Analysis (WDA) to analyze categories of domains with secondary purposes and no ideal grain of decomposition. This difficulty encouraged us to pursue Control Task (ConTA) and Strategies (StrA) analysis, which are under-explored as bases for interface design. In ConTA we found M&T was best represented by two interlinked work functions; one controlling energy, the other maintaining knowledge representations. From StrA, we identified a popular representation-dependent strategy and inferred information required to diagnose faults in system performance and knowledge representation. This article presents and discusses excerpts from our analysis, and outlines their application to diagnosis support tools. Copyright © 2015 Elsevier Ltd. All rights reserved.

  12. A new genus of Eastern Hemisphere stingless bees (Hymenoptera, Apidae), with a key to the supraspecific groups of Indomalayan and Australasian Meliponini

    DEFF Research Database (Denmark)

    Rasmussen, Claus; Thomas, Jennifer C.; Engel, Michael S.

    2017-01-01

    and is more closely related to Lepidotrigona Moure. The species is transferred to Wallacetrigona Engel and Rasmussen, new genus, and differentiated from Geniotrigona proper as well as all other meliponines occurring in Sundaland, Wallacea, and Sahul (Australinea). The new genus occurs east of the Wallace Line...... and separate from the distribution of Geniotrigona, which is otherwise restricted to Sundaland, but Wallacetrigona is presently not known beyond the Weber Line. A hierarchical classification of Indomalayan and Australasian stingless bees is tabulated and a revised key to the genera and subgenera provided......, as well as an appendix tabulating the species and synonyms. The following new combinations are established: Wallacetrigona incisa (Sakagami and Inoue), Homotrigona (Lophotrigona) canifrons (Smith), Homotrigona (Odontotrigona) haematoptera (Cockerell), Homotrigona (Tetrigona) apicalis (Smith), H. (T...

  13. The reoccurance of pre-welfare state poverty profiles in Denmark?

    DEFF Research Database (Denmark)

    Christensen, Anders Bøggild

    2011-01-01

    on universalism, progressive taxation and extensive social benefits is often regarded to perform well at preventing poverty problems and inequality (Goul Andersen 2003). Comparative research shows Denmark and the Nordic welfare states as countries with low levels of poverty and inequality (OECD 2008, Fritzell...... & Ritakallio 2010). Recent research has shown increasing levels of poverty and rising inequality in Denmark during the past decade (Ministry of Finance, 2009). These tendencies seem to be relatively small in scale, which is why it doesn’t disturb the picture of a relatively effective welfare state. However...... this picture only stands at the general level. New research reveal very high and increasing poverty rates for minority subgroups which are often covered in the general studies. Under the surface it seems as an increasing social polarisation is appearing in the larger cities of Denmark (Rasmussen 2011...

  14. Durability of cracked fibre reinforced concrete structures

    DEFF Research Database (Denmark)

    Hansen, Ernst Jan De Place

    1998-01-01

    Durability studies are carried out at BKM as part of the research project "Design Methods for Fibre Reinforced Concrete" (FRC) involving BKM, The Concrete Research Center at DTI, Building Technology at Aalborg University, Rambøll, 4K-Beton and Rasmussen & Schiøtz. Concrete beams with or without...... fibre reinforcement are exposed to a combination of mechanical and environmental load to indicate whether fibre reinforcement will improve the durability of cracked concrete structures. Secondly, it is the aim to identify important mechanisms for the effect of the fibre reinforcement on the durability......) and polypropylene fibres (PP) are used in the concrete beams as well as main reinforcement. Results of the durability tests on cracked FRC-beams are compared with results for uncracked FRC-beams and beams without fibres....

  15. Teacher expertise

    DEFF Research Database (Denmark)

    Rasmussen, Jens

    and practice through development of better models for bridging the teaching at college and the internship teaching. The study was a longitudinal research and development project that followed teacher students during their first three years of a four year teacher education program after the teacher education...... reform of 2007. The study included four teacher training colleges at two university colleges and about 100 students. In the reform and in the study focus was on professional development. Each of the colleges implemented a number of actions in order to see whether they had potential for bridging the gap......Teacher Expertise: How to improve the relationship between Theory and Practice in Teacher Education Jens Rasmussen, Department of Education, Aarhus University In several studies and reports it has been nailed over and over that teachers’ matter. So this is not the question in this study...

  16. CONGESTIVE HEART FAILURE IN DOGS IS ASSOCIATED WITH INCREASED PLATELET LEUKOCYTE AGGREGATION MEASURED BY FLOW CYTOMETRY

    DEFF Research Database (Denmark)

    Tarnow, Inge; Andreasen, Susanne SH; Olsen, Lisbeth Høier

    2010-01-01

    , platelet activation markers have not been investigated in dogs with clinical signs of heart disease. We hypothesized that platelet surface activation markers are higher in dogs with CHF compared to age-matched controls without clinical signs of heart failure. Dogs with compensated congestive heart failure......CONGESTIVE HEART FAILURE IN DOGS IS ASSOCIATED WITH ENHANCED PLATELET-LEUKOCYTE AGGREGATES - A MARKER FOR PLATELET ACTIVATION. I Tarnow1, LH Olsen2, SHS Andreasen2, SG Moesgaard2, CE Rasmussen2, AT Kristensen1, T Falk2. 1Departments of Small Animal Clinical Sciences and 2Animal and Veterinary Basic...... Sciences, Faculty of Life Science, University of Copenhagen, Denmark. Chronic congestive heart failure (CHF) in humans is associated with abnormal hemostasis, and changes in hemostatic biomarkers carry a poor prognosis. CHF in dogs has been associated with plasma markers of hypercoagulability, however...

  17. Application of the PE method to up-slope sound propagation

    DEFF Research Database (Denmark)

    Rasmussen, Karsten Bo; Arranz, Marta Galindo

    1995-01-01

    The wide-angle PE method is applied to the prediction of sound propagation in a range-dependent environment. The finite-difference model treats the sloping ground by a staircase approximation. The method allows impedance and slope angle variations to be taken into account. The implementation...... velocity at the surface. The staircase PE method approximates the normal at the slope surface with the vertical component at the stair-step surface. A numerical correction can be included. Using a scale model facility [K. B. Rasmussen, 3617–3620 (1994)], a series of measurements is carried out. The results...... of sloping interfaces in one-way PE models introduces a fundamental problem of energy conservation. This is generated at the lower boundary condition. The ground is assumed to be a locally reacting surface where the ground impedance is defined as the ratio of pressure to the normal component of particle...

  18. Guiding young adults at risk

    DEFF Research Database (Denmark)

    Andreasen, Karen Egedal; Rasmussen, Palle Damkjær; Ydesen, Christian

    2016-01-01

    Karen Egedal Andreasen, Palle Rasmussen and Christian Ydesen question in their article, how to guide youth in danger of being marginalised or excluded from society in general and the labour market in particular. They analyse the guidance dimension in the youth in development project as described...... in the project and by the youths participating in the project. The project was designed to facilitate and support transition to an adult life by giving participants social support, feedback, experiences, room for reflection and feeling of acceptance and inclusion. In Denmark all social work with young people...... at risk involves guidance to “the right path”, since individual guidance seems to be the key asset in mobilizing young person’s needs and experiences. The article indicates important elements in the guidance of youth at risk, such as psychological intervention and personal support, support from...

  19. Approximate simulation of Hawkes processes

    DEFF Research Database (Denmark)

    Møller, Jesper; Rasmussen, Jakob Gulddahl

    2006-01-01

    Hawkes processes are important in point process theory and its applications, and simulation of such processes are often needed for various statistical purposes. This article concerns a simulation algorithm for unmarked and marked Hawkes processes, exploiting that the process can be constructed...... as a Poisson cluster process. The algorithm suffers from edge effects but is much faster than the perfect simulation algorithm introduced in our previous work Møller and Rasmussen (2004). We derive various useful measures for the error committed when using the algorithm, and we discuss various empirical...... results for the algorithm compared with perfect simulations. Extensions of the algorithm and the results to more general types of marked point processes are also discussed....

  20. Fy, skam dig ikke!

    DEFF Research Database (Denmark)

    Villadsen, Lisa Storm

    2018-01-01

    -udmeldingen indebærer for kollektivet. Den anden er statsminister Lars Løkke Rasmussens Grundlovstale 2016. Fra en retorisk medborgerskabsvinkel er det interessant både at statsministeren tager det op, og hvordan han gør det. Visse samfundsfilosoffer, bl.a. John Rawls og Martha Nussbaum har, på linje med retorikken......, argumenteret for det indlysende i at samfundslivet generelt og politik mere specifikt ikke kan tænkes uden følelser. I sin bog Political Emotions understreger Nussbaum at ’offentlige følelser’ findes overalt i liberale demokratier og bl.a. knytter sig til politiske principper. Et andet, men relateret...

  1. The transition between undiluted and oligomer-diluted states of nearly monodisperse polystyrenes in extensional flow

    DEFF Research Database (Denmark)

    Huang, Qian; Rasmussen, Henrik K.

    2017-01-01

    We have measured the startup and steady extensional viscosity of two narrow molar mass distributed (NMMD) polystyrenes, a 910 kg/mole and a 545 kg/mole, diluted in a NMMD 4.29 kg/mole styrene oligomer, with a wide concentration range from 90 down to 17%. The constant interchain pressure model......, proposed by Rasmussen and Huang (Rheol Acta 53(3):199–208 (2014a)), predicts the extensional viscosity well for the dilutions with lower concentrations. However, for the 70 and 90% 545 kg/mole samples which represent the transition between the diluted and undiluted states, the model predictions are less...... satisfactory. Another concept based on interchain pressure, proposed by Wagner (Rheol Acta 53(10):765–777 (2014)), also shows agreement with the measured data....

  2. Chilled Ammonia Process for CO2 Capture

    DEFF Research Database (Denmark)

    Darde, Victor Camille Alfred; Thomsen, Kaj; Well, Willy J.M. van

    2010-01-01

    The chilled ammonia process absorbs the CO2 at low temperature (2–10°C). The heat of absorption of carbon dioxide by ammonia is significantly lower than for amines. In addition, degradation problems can be avoided and a high carbon dioxide capacity is achieved. Hence, this process shows good...... perspectives for decreasing the heat requirement. However, a scientific understanding of the processes is required. The thermodynamic properties of the NH3–CO2–H2O system were described using the extended UNIQUAC electrolyte model developed by Thomsen and Rasmussen in a temperature range from 0 to 110°C...... and pressure up to 100bars. The results show that solid phases consisting of ammonium carbonate and bicarbonate are formed in the absorber. The heat requirements in the absorber and in the desorber have been studied. The enthalpy calculations show that a heat requirement for the desorber lower than 2GJ/ton CO2...

  3. How Repeated Time To Event (RTTE) modelling of opioid requests after surgery may improve future post-operative pain management

    DEFF Research Database (Denmark)

    Juul, Rasmus Vestergaard; Rasmussen, Sten; Kreilgaard, Mads

    Title: How Repeated Time To Event (RTTE) modelling of opioid requests after surgery may improve future post-operative pain management Author: Rasmus Vestergaard Juul (1) Sten Rasmussen (2) Mads Kreilgaard (1) Ulrika S. H. Simonsson (3) Lona Louring Christrup (1) Trine Meldgaard Lund (1) Institution...... to Event (RTTE) modelling2 approach of repeated opioid request in order to increase the understanding of pain breakthrough patterns in severe surgeries and improve patients’ pain management. Methods: 68 patients (F:45,M:23, Age:76±15) were included from a population receiving surgery after hip fracture...... in NONMEM 7.2 with Pirana, PsN and Xpose- and ggplot2 libraries for R3,4. Weibull and Gompertz distributions were investigated as hazard models. Visual Predictive Check (VPC) of Kaplan Meier survival curves as well objective function value was used to evaluate the model fit. Results: A base RTTE model based...

  4. Danish Ultras

    DEFF Research Database (Denmark)

    Havelund, Jonas; Joern, Lise; Rasmussen, Kristian

    2012-01-01

    It is well documented that knowledge of supporter culture is crucial when assessing the risk of disorder at football matches and thereby ensuring a balanced approach by police and stewards (Stott & Pearson 2007). Both within Denmark and internationally, there is a weak understanding of risk...... supporters, often resulting in inappropriate assessments on the part of the police. This has led to conflicts that presumably could have been avoided had the police possessed a deeper awareness of supporter culture (Stott & Pearson 2007; Rasmussen, Havelund & Tranegaard Andersen 2009). This article...... is the result of a qualitative study of the self-declared nonviolent segment of the Danish risk supporters, i.e. the ultra culture. The study’s empirical data stems from qualitative interviews and participant observation primarily focusing at matches involving Brøndby IF, the club supported by the interviewees...

  5. Integration of strategy experiential learning in e-module of electronic records management

    Directory of Open Access Journals (Sweden)

    S. Sutirman

    2018-01-01

    Full Text Available This study aims to determine the effectiveness of e-module of electronic records management integrated with experiential learning strategies to improve student achievement in the domain of cognitive, psychomotor, and affective. This study is a research and development. Model research and development used is Web-Based Instructional Design (WBID developed by Davidson-Shivers and Rasmussen. The steps of research and development carried out by analysis, evaluation planning, concurrent design, implementation, and a summative evaluation. The approach used in this study consisted of qualitative and quantitative approaches. Collecting data used the Delphi technique, observation, documentation studies and tests. Research data analysis used qualitative analysis and quantitative analysis. Testing the effectiveness of the product used a quasi-experimental research design pretest-posttest non-equivalent control group. The results showed that the e-module of electronic records management integrated with experiential learning strategies can improve student achievement in the domain of cognitive, psychomotor, and affective.

  6. Pensionisters levevilkår i seks EU-lande

    DEFF Research Database (Denmark)

    Rasmussen, Martin

    I arbejdspapiret beskrives økonomiske forhold, sociale relationer og helbredsmæssige forhold for pensionister i seks EU-lande. Sammenligningen sker på flere måder. Dels sammenlignes niveauerne i de seks lande; er danske pensionister fx rigere, eller mere ensomme end i andre lande? Dels sammenlignes...... indkomstforskellene for sociale relationer og helbred i forskellige lande; er forskellen på rige og fattige danske pensionisters helbred mindre end i andre lande? Arbejdspapiret er et baggrundspapir for kapitel 7 i rapporten ”Levevilkår for pensionister uden supplerende indkomst” af Jacob Nielsen Arendt m.......fl. Rapporten er udarbejdet af Amternes og Kommunernes Forskningsinstitut og Socialforskningsinstituttet for Socialministeriet. Den væsentligste forskel på arbejdspapiret og rapporten er, at en række statistiske test er beskrevet grundigere i papiret. Arbejdspapiret er skrevet af forsker Martin Rasmussen...

  7. Transformation in the management of Danish public-sector

    DEFF Research Database (Denmark)

    Andersen, Vibeke; Hindhede, Anette Lykke

    2016-01-01

    -making in this sector can therefore be seen as very challenging. According to Greve and Ejersbo's (2013) concept coordination and cooperation, a newer type of leadership has emerged with an understanding that we have common challenges and that output measurements can help in managing the sector. Included in this new...... type of leadership is the assumption that measurements should be carried out on the collective results of the group rather than focusing on the individual. New public management’s focus on market mechanisms and liberal policies, such as outsourcing and privatization, has thus been replaced...... by an increased focus on the efficient use of resources. The perception within this kind of leadership is that there must be change not only in the sector’s structural conditions but also in the actual execution of the work (Andersen & Jensen, 2010; Christiansen, 2012; Hagedorn-Rasmussen, 2014). In this context...

  8. Higher molecular weight dissolved organic nitrogen turnover as affected by soil management history

    DEFF Research Database (Denmark)

    Lønne Enggrob, Kirsten

    High molecular weight dissolved organic nitrogen turnover as affected by soil management history *Kirsten Lønne Enggrob,1 Lars Elsgaard,1 and Jim Rasmussen1 1Aarhus University, Dept. of Agroecology, Foulum, Denmark 1. Introduction Dissolved organic nitrogen (DON) play an important role in soil N...... cycling. DON, as a collective term, refers to a diversity of organic N compounds which can operationally be grouped into high molecular weight (Mw) DON (Mw > 1 kDa) and low Mw DON (... are presented for 14CO2 evolution during 14 days of incubation. 4. Results and conclusion Results showed that the turnover rate of high Mw DON was dependent on both the Mw size of DON and on the soil liming history. Evidence showing where in the DON Mw sizes the bottleneck lies will be presented....

  9. Arctic Sea ice by passive microwave observations from the Nimbus-5 Satellite

    Science.gov (United States)

    Campbell, W. J.; Gloersen, P.; Zwally, H. J.

    1983-01-01

    The results of a dynamic/thermodynamic numerical model of Arctic sea ice are compared with satellite images from the Nimbus 5 electrically scanning microwave radiometer. The model combines aspects of two previous sea ice models those of Parkinson and Washington and Ling, Rasmussen, and Campbell. A solid/fluid model basically follows the formulation of the Parkinson and Washington model with the addition of the constitutive equation and equation of state from the Ling model. The Parkinson and Washington model simulates the seasonal cycle of sea ice thicknesses and concentrations with a horizontal resolution of roughly 200 km and a timestep of 8 hours. The thermodynamics are calculated through energy balances at the interfaces between ice and air, water and ice, and water and air. The ice dynamics are calculated through a momentum equation balancing air stress, water stress, dynamic topography, and Coriolis force, with an adjustment for internal ice resistance.

  10. Excerpt from Queequeg’s Coffin: Indigenous Literacies and Early American Literature

    Directory of Open Access Journals (Sweden)

    Birgit Brander Rasmussen

    2012-06-01

    Full Text Available Birgit Brander Rasmussen’s Queequeg’s Coffin: Indigenous Literacies and Early American Literature is a fascinating discussion of various non-alphabetic writing by indigenous peoples. According to its blurb, it “recovers previously overlooked moments of textual reciprocity in the colonial sphere, from a 1645 French-Haudenosaunee Peace Council to Herman Melville’s youthful encounters with Polynesian hieroglyphics.” The text reproduced here takes on Melville’s iconic novel Moby Dick and explores Ishmael’s description of the tattoos on the body of the Polynesian harpooner Queequeg and on his coffin. Rasmussen posits these as a fictionalized embodiment of actual Polynesian writing.

  11. In-Hospital Basic Life Support: Major Differences in Duration, Retraining Intervals, and Training Methods - A Danish Nationwide Study

    DEFF Research Database (Denmark)

    Rasmussen, Ditte K; Glerup Lauridsen, Kasper; Staerk, Mathilde

    2017-01-01

    Introduction: High-quality chest compressions and early defibrillation is essential to improve survival following in-hospital cardiac arrest. Efficient training in basic life support (BLS) for clinical staff is therefore important. This study aimed to investigate duration, training methods......%) or on a gurney (29%). Backboards were used in 2% of hospitals. Work position during chest compressions was part of training, and included adjusting the bed height (70%), removing the bed rail (59%), and/or jumping onto the bed (41%). CPR feedback devices were used by 85%. An end-of-course test for BLS skills...... different methods to optimize work position. Backboards are very rarely used. Most hospitals did not use end-of-course tests for BLS skills.Author Disclosures: D.K. Rasmussen: None. K.G. Lauridsen: None. M. Staerk: None. T. Mygind: None. B. Loefgren: None....

  12. Activation of satellite cells and the regeneration of human skeletal muscle are expedited by ingestion of nonsteroidal anti-inflammatory medication

    DEFF Research Database (Denmark)

    Mackey, Abigail L; Rasmussen, Lotte Klejs; Kadi, Fawzi

    2016-01-01

    muscles of one leg. Muscle biopsies were collected from the vastus lateralis muscles before and after stimulation (2.5 h and 2, 7, and 30 d) and were assessed for satellite cells and regeneration by immunohistochemistry and real-time RT-PCR, and we also measured telomere length. After injury, and compared...... activation of satellite cells and muscle remodeling during large-scale regeneration of injured human skeletal muscle.-Mackey, A. L., Rasmussen, L. K., Kadi, F., Schjerling, P., Helmark, I. C., Ponsot, E., Aagaard, P., Durigan, J. L. Q., Kjaer, M. Activation of satellite cells and the regeneration of human......With this study we investigated the role of nonsteroidal anti-inflammatory drugs (NSAIDs) in human skeletal muscle regeneration. Young men ingested NSAID [1200 mg/d ibuprofen (IBU)] or placebo (PLA) daily for 2 wk before and 4 wk after an electrical stimulation-induced injury to the leg extensor...

  13. United Space Alliance waits to test its one-man submarine for SRB retrieval

    Science.gov (United States)

    2000-01-01

    The one-man submarine dubbed DeepWorker 2000 sits on the deck of Liberty Star, one of two KSC solid rocket booster recovery ships. Inside the sub is the pilot, Anker Rasmussen. The sub is being tested on its ability to duplicate the sometimes hazardous job United Space Alliance (USA) divers perform to recover the expended boosters in the ocean after a launch. The boosters splash down in an impact area about 140 miles east of Jacksonville and after recovery are towed back to KSC for refurbishment by the specially rigged recovery ships. DeepWorker 2000 was built by Nuytco Research Ltd., North Vancouver, British Columbia. It is 8.25 feet long, 5.75 feet high, and weighs 3,800 pounds. USA is a prime contractor to NASA for the Space Shuttle program.

  14. The Military's Business

    DEFF Research Database (Denmark)

    Rasmussen, Mikkel Vedby

    South' or utilising new technologies to overcome the prohibitive costs of current systems. Analysing the philosophical, strategic and budgetary underpinnings of these alternatives, he concludes that a more radical break from current military organisational practices is needed which would allow them......If the military were a business, would you buy shares? Over recent years, Western armed forces, particularly the US, have been costing more yet achieving less. At the same time, austerity measures are reducing defence budgets. This book uses defence data to examine the workings of modern Western...... militaries and explore what kind of strategies can overcome this gap between input and output. Instead of focusing on military strategy, Mikkel Vedby Rasmussen seeks to draw on the ideas of business strategy to assess alternative business cases - reforming military HR to combat instability in the 'Global...

  15. Hemoptysis Caused by Leech Infestation: A Unique Case

    Directory of Open Access Journals (Sweden)

    Latif Moini

    2013-04-01

    Full Text Available Hemoptysis in the patients suffered from pulmonary tuberculosis (TB may be resulted by active TB or the complications of such disease which appears as bronchiectasis, fungal lesions deployed in tuberculosis cavities or Rasmussen aneurysm, Bronchiolitis or relapse and sometimes, it may be considered as caused by reasons irrelevant to TB. In this report, the patient is a 69-year-old man as complained of hemoptysis with a treated TB experience that was found as normal in the preliminary review of X-ray and CT. During bronchoscopy, a live leech (bloodsucker was found in hypopharynx area that was swallowed after repeated attempts to remove it through the gastrointestinal tract and its suction signs were appeared as a mucosal mass in the hypopharynx area. The patient had no symptoms during his stay in the hospital.

  16. To be or not to be relevant

    DEFF Research Database (Denmark)

    Kann-Rasmussen, Nanna

    What is the purpose and legitimacy of arts and culture in society today? Do arts and culture have a role to play relation to social and political purposes? Alternatively, do the arts represent an absolute otherness in relation to the rest of society? Artists and scholars have discussed...... the assumption that the encounter between citizens and culture or the arts would ‘build’ and empower the individual, and thus contribute to the strengthening of democratic society. Cultural policy thus largely followed this line through arms-length support for arts and artists (the producers) as well...... for a cultural institution to be societally relevant. According to Kann-Rasmussen (2016), the term ‘societal relevance’ signifies two meanings. The term covers cultural institutions’ contribution to cultural policy’s original purpose of ensuring public enlightenment and education, and it relates to cultural...

  17. Climate vs. tectonic induced variations in Cenozoic sediment supply from western Scandinavia

    DEFF Research Database (Denmark)

    Gołędowski, Bartosz; Nielsen, S.B.; Clausen, O.R.

    -22] and floral assemblages [23]. The Paleocene and Eocene epochs were times of warm climates, peaking in the Late Paleocene Thermal Maximum [21]. A rapid cooling on the Eocene-Oligocene transition changed the global conditions from ‘greenhouse’ to ‘icehouse’, resulting in glaciers reaching sea level in East......-36. 12. Riis, F., Quantification of Cenozoic vertical movements of Scandinavia by correlation of morphological surfaces with offshore data. Global and Planetary Change, 1996. 12(1-4): p. 331-357. 13. Rasmussen, E.S., The interplay between true eustatic sea-level changes, tectonics, and climatic changes...... Greenland [24] as well as in increased seasonality through colder winters [25]. After a subsequent warming in late Oligocene and Early Miocene the climate started to deteriorate after the Mid-Miocene Climatic Optimum towards the Pliocene when the North Hemisphere Glaciation begun and the frequency...

  18. Flexicurity in the Current Economic and Social Context

    Directory of Open Access Journals (Sweden)

    Georgeta Modiga

    2015-05-01

    Full Text Available The flexicurity concept - an abbreviation between flexibility and security - appeared in the early 90s, being used for the first time by the Danish Prime Minister Poul Nyrum Rasmussen. The concept refers to a social state model that promotes a pro-active policy in the labour domain and the access to employment. Flexicurity can be defined as a strategy integrated by the simultaneous consolidation of flexibility and security on the labour market. According to the definition given by the European Commission, which establishes the guidelines and “paths” typical for the Member States in order to develop their own strategies in the field, flexicurity is an integrated strategy of simultaneous strengthening of flexibility and security on labour market. This concept arose as a result of socio-economic changes registered in the last decades in Europe: globalization and European integration, development of new technologies, the demographic aging of European society, the segmented development of labour markets.

  19. Variation and correlation of hydrologic properties

    Energy Technology Data Exchange (ETDEWEB)

    Wang, J.S.Y. [Lawrence Berkeley Lab., CA (United States)

    1991-06-01

    Hydrological properties vary within a given geological formation and even more so among different soil and rock media. The variance of the saturated permeability is shown to be related to the variance of the pore-size distribution index of a given medium by a simple equation. This relationship is deduced by comparison of the data from Yucca Mountain, Nevada (Peters et al., 1984), Las Cruces, New Mexico (Wierenga et al., 1989), and Apache Leap, Arizona (Rasmussen et al., 1990). These and other studies in different soils and rocks also support the Poiseuille-Carmen relationship between the mean value of saturated permeability and the mean value of capillary radius. Correlations of the mean values and variances between permeability and pore-geometry parameters can lead us to better quantification of heterogeneous flow fields and better understanding of the scaling laws of hydrological properties.

  20. Heart Rate Variability in Cavalier King Charles Spaniels with Different Degree of Myxomatous Mitral Valve Disease

    DEFF Research Database (Denmark)

    Rasmussen, Caroline Elisabeth; Falk, Bo Torkel; Zois, Nora Elisabeth

    2010-01-01

    Heart Rate Variability in Cavalier King Charles Spaniels with Different Degree of Myxomatous Mitral Valve Disease Rasmussen, C.E. 1, Falk, T. 1, Zois, N.E. 1, Moesgaard, S.G. 1, Häggström, J. 2, Pedersen, H.D. 3 and Olsen, L.H1. 1Department of Basic Animal and Veterinary Sciences, Faculty of Life...... variability (HRV). Reduced HRV is seen in dogs with heart failure secondary to myxomatous mitral valve disease (MMVD). However, HRV is suggested to increase with disease progression in dogs with early stages of MMVD. Comparable results are found in people with primary mitral valve prolapse, a disease...... into 4 groups: 1) no or minimal mitral regurgitation (MR) (MR jet=15% of the left atrial area) and no murmur, 2) mild MR (20%50%) and no clinical signs of heart failure, 4) left atrium to aortic root ratio >1.5, clinical signs of heart failure and furosemide...

  1. Evaluation of Test Method for Solar Collector Efficiency

    DEFF Research Database (Denmark)

    Fan, Jianhua; Shah, Louise Jivan; Furbo, Simon

    on these efficiencies, an efficiency equation is determined by regression analysis. In the test method, there are no requirements on the ambient air temperature and the sky temperature. The paper will present an evaluation of the test method for a 12.5 m² flat plate solar collector panel from Arcon Solvarme A....../S. The solar collector panel investigated has 16 parallel connected horizontal absorber fins. CFD (Computational Fluid Dynamics) simulations, calculations with a solar collector simulation program SOLEFF (Rasmussen and Svendsen, 1996) and thermal experiments are carried out in the investigation......The test method of the standard EN12975-2 (European Committee for Standardization, 2004) is used by European test laboratories to determine the efficiency of solar collectors. In the test methods the mean solar collector fluid temperature in the solar collector, Tm is determined by the approximated...

  2. The Military's Business

    DEFF Research Database (Denmark)

    Rasmussen, Mikkel Vedby

    If the military were a business, would you buy shares? Over recent years, Western armed forces, particularly the US, have been costing more yet achieving less. At the same time, austerity measures are reducing defence budgets. This book uses defence data to examine the workings of modern Western...... militaries and explore what kind of strategies can overcome this gap between input and output. Instead of focusing on military strategy, Mikkel Vedby Rasmussen seeks to draw on the ideas of business strategy to assess alternative business cases - reforming military HR to combat instability in the 'Global...... South' or utilising new technologies to overcome the prohibitive costs of current systems. Analysing the philosophical, strategic and budgetary underpinnings of these alternatives, he concludes that a more radical break from current military organisational practices is needed which would allow them...

  3. School Me, School Me Not, Street Me, Street Me Not…

    DEFF Research Database (Denmark)

    Gravesen, David Thore; Frostholm, Peter Hornbæk

    School Me, School Me Not, Street Me, Street Me Not… (1099) David Thore Gravesen, Peter Hornbæk Frostholm ECER 2016, 14. Communities, Families and Schooling in Educational Research, Session: 14 SES 10 A When picking leaves of a marguerite, whilst doing the “she loves me, she loves me not” game, you...... tend to let coincidence or perhaps destiny have a final say. But what are the determinants, when you face the thrill of having to choose your future? Youth is a period of transition and important decisions related to education and future engagement. For some, this challenge is fairly straightforward...... milieu. With a criminal gang-like behavior (Hoeben & Weerman 2013; Hviid 2007; Rasmussen 2012) involving petty crime and violence, one would think the group members would be indifferent towards their schooling and future careers. This was not the case. The informants proved to be very aware...

  4. Certified Basic Life Support Instructors Assess Cardiopulmonary Resuscitation Skills Poorly

    DEFF Research Database (Denmark)

    Hansen, Camilla; Rasmussen, Stinne E; Kristensen, Mette Amalie

    2016-01-01

    Introduction: High-quality cardiopulmonary resuscitation (CPR) improves survival from cardiac arrest. During basic life support (BLS) training, instructors assess CPR skills to enhance learning outcome. Emergency department staff and senior residents have been shown to assess chest compression...... out of 3 CPR cycles with 30±2 chest compressions at a depth of 50-60mm and rate of 100-120 min-1. Correct rescue breathing was defined as ≥50% efficient breaths in 3 CPR cycles with visible, but not excessive, manikin’s chest raise (for instructors) or a volume of 500-600 mL (manikin data).Results: We...... of CPR skills may be beneficial to ensure high-quality learning outcome.Author Disclosures: C. Hansen: None. S.E. Rasmussen: None. M.A. Nebsbjerg: None. M. Stærk: None. B. Løfgren: None....

  5. Means and ends of control

    DEFF Research Database (Denmark)

    Lind, Morten

    2004-01-01

    Means-end analysis plays a significant role in cognitive engineering and has been successfully applied in several work domains, usually in the form of Rasmussens abstraction hierarchy. However, work domains with embedded controls create problems and modifications of the abstraction hierarchy has...... been proposed to circumvent the problems. But embedded controls is a deep problem for means-end analysis in general and not only for instances like the abstraction hierarchy. It is pointed out that means-end analysis is currently not used in control engineering but should be used to clarify modelling...... assumptions. Means-end analysis also lacks a proper definition of the control concept. It is proposed that control is defined as a binary relation that assign functional roles to subsystems. This control concept leads to distinct but entangled process and control hierarchies. It is argued that the problems...

  6. Comparative evaluation of low-molecular-mass proteins from Mycobacterium tuberculosis identifies members of the ESAT-6 family as immunodominant T-cell antigens

    DEFF Research Database (Denmark)

    Skjøt, R L; Oettinger, T; Rosenkrands, I

    2000-01-01

    . The molecules were characterized, mapped in a two-dimensional electrophoresis reference map of short-term culture filtrate, and compared with another recently identified low-mass protein, CFP10 (F. X. Berthet, P. B. Rasmussen, I. Rosenkrands, P. Andersen, and B. Gicquel. Microbiology 144:3195-3203, 1998......), and the well-described ESAT-6 antigen. Genetic analyses demonstrated that TB10.4 as well as CFP10 belongs to the ESAT-6 family of low-mass proteins, whereas TB7.3 is a low-molecular-mass protein outside this family. The proteins were expressed in Escherichia coli, and their immunogenicity was tested......Culture filtrate from Mycobacterium tuberculosis contains protective antigens of relevance for the generation of a new antituberculosis vaccine. We have identified two previously uncharacterized M. tuberculosis proteins (TB7.3 and TB10.4) from the highly active low-mass fraction of culture filtrate...

  7. Commentary

    DEFF Research Database (Denmark)

    Rasmussen, Jens

    1993-01-01

    basically to understand the cognitive process and cooperative patterns of the actors in work, and to develop a framework for design of advanced information systems. The work contributed to a CEC basic research action project; MOHAWC; modeling human activities in work context (Rasmussen et al., 1991...... in the research paradigms than to extend the scope of the human factors profession to encompass total socio-technical systems. This conclusion is not in contradiction to the arguments in the articles reviewed, but calls for a substantial extension.......I have been asked to contribute my observations to this special issue on human factors in manufacturing based on the reading of four contributed articles. My comments are based on our field studies in process plants, hospitals, manufacturing companies and public libraries. Theses studies were made...

  8. Elasto-plastic hardening models adjustment to ferritic, austenitic and austenoferritic Rebar

    Directory of Open Access Journals (Sweden)

    Beatriz Hortigón

    2017-05-01

    Full Text Available The elastoplastic behaviour of steel used for structural member fabrication has received attention to facilitate a mechanical-resistant design. New Zealand and South African standards have adopted various theoretical approaches to describe such behaviour in stainless steels. With respect to the building industry, describing the tensile behaviour of steel rebar used to produce reinforced concrete structures is of interest. Differences compared with the homogenous material described in the above mentioned standards and related literatures are discussed in this paper. Specifically, the presence of ribs and the TEMPCORE® technology used to produce carbon steel rebar may alter the elastoplastic model. Carbon steel rebar is shown to fit a Hollomon model giving hardening exponent values on the order of 0.17. Austenitic stainless steel rebar behaviour is better described using a modified Rasmussen model with a free fitted exponent of 6. Duplex stainless steel shows a poor fit to any previous model.

  9. Bridging a gap between theory and practice in mathematics teacher education

    DEFF Research Database (Denmark)

    Jóelsdóttir, Lóa Björk; Errebo-Hansen, Dorthe; Westphael, Henning

    Bridging the dichotomy of theory and practices has long been a key issue of the research in teacher education both in general and within mathematics education (Østergaard, 2016). In the15th ICMI Study (Even & Ball, 2009) there is brief discussion of this dichotomy in (Ponte et al, 2009) but mainly...... the perspective is either on students learning from practice or students learning in an educational programme, which we see as an example of the dichotomy between theory and practices often seen in research of mathematics teacher education. In studies, focusing on bridging the gap often it is seen being...... on students reflecting on their own practice (Rasmussen, 2016) or on students own understanding of - or views on the gap between theory and practice (Østergaard 2016). One study is found to address student development both in an educational context (method course) as well as in a practices context (weekly...

  10. A cultural turn? Vocational teacher education in Denmark

    DEFF Research Database (Denmark)

    Duch, Henriette

    As part of my Ph.D.-project the field of educational policy is analysed with a focus on the decision process on a change of vocational teacher education (Bourdieu, 1996; Duch and Rasmussen, XX). The process is seen in the light of the Bologna process. Originally, the education of Danish vocational...... teachers was a specialized and non-classified course, now it is classifies as a higher education at level six in the Danish Qualification Framework. The analysis is based on qualitative interviews with representatives of for example vocational teachers and of leaders at vocational colleges – different......´ and ´from above´ and Smeby and Heggens approach to coherence (Evetts 2003; Heggen, Smeby, 2015). It can be discussed, if the change of teacher education in Denmark demands new approaches as coherence and theories of professions instead of situated learning. However, it is important to discuss...

  11. Training the Trainers - from an EU Perspective

    DEFF Research Database (Denmark)

    Martinsen, Bodil

    trainers have to be made available to them. The aim of this paper is to present the EU project, AGIS II, Making things happen: Training the trainers of legal interpreters and translators throughout the EU, coordinated by Kirsten W. RAsmussen and Bodil Martinsen, associate professors at the Department...... the implementation process of the recommendations put forward by developing concrete guidelines and materials for training and assessment of not only legal interpreters and translators but also of those working with interpreters and translators within the legal services and sharing the responsibility for the quality...... the establishment of recognised and EU-consistent training and assessment of, among others, legal interpreters and translators based on equivalent standards. This paper presents a project which forms a solid platform for future action to enhance the quality of the services rendered by legal interpreters...

  12. Global temperatures and the global warming ``debate''

    Science.gov (United States)

    Aubrecht, Gordon

    2009-04-01

    Many ordinary citizens listen to pronouncements on talk radio casting doubt on anthropogenic global warming. Some op-ed columnists likewise cast doubts, and are read by credulous citizens. For example, on 8 March 2009, the Boston Globe published a column by Jeff Jacoby, ``Where's global warming?'' According to Jacoby, ``But it isn't such hints of a planetary warming trend that have been piling up in profusion lately. Just the opposite.'' He goes on to write, ``the science of climate change is not nearly as important as the religion of climate change,'' and blamed Al Gore for getting his mistaken views accepted. George Will at the Washington Post also expressed denial. As a result, 44% of U.S. voters, according to the January 19 2009 Rasmussen Report, blame long-term planetary trends for global warming, not human beings. Is there global cooling, as skeptics claim? We examine the temperature record.

  13. Londres, ciudad única. Crítica de libros

    Directory of Open Access Journals (Sweden)

    Antón Capitel

    2011-10-01

    Full Text Available This book by Rasmunssen examines London with an extraordinary spatial expanse, character-ized by its free and original layout, made up of the union of different towns, and with an abun-dance of free spaces. It is an interesting analysis of the British capital, which examines small urban structures such as squares with a special emphasis, as well as their attractive vertical houses. The author of the review makes note of the passion shown by Rasmussen, which causes him to forget certain defects present within the city, such as the positive view upon the continuity of the layout found in the City. The author finds this last element to be something negative, which explains the unsatisfactory present situation. It also explains the unconvincing Victorian London, which the Danish professor ignores, as well as the inability to convert the river into a true city center after having relegated Southwark to the condition of a suburb.

  14. Street Cries and the urban refrain

    DEFF Research Database (Denmark)

    Kreutzfeldt, Jacob

    2012-01-01

    Street cries, though rarely heard in North European cities today, testify to ways in which audible practices shape and structure urban space. As paradigmatic for what Gilles Deleuze and Felix Guattari call the refrain, the ritualized and stylized practice of street cries may point at the dynamics...... of space-making, through which the social and territorial construction of urban space is performed. The article draws on historical material documenting and describing street cries, particularly in Copenhagen round 1929 to 1935. Most notably, the composer Vang Holmboe and the architect Steen Eiler...... Rasmussen have investigated Danish street cries as respectably a musical and a spatial phenomenon. Such studies – from each their perspectives – can be said to explore the aesthetics of urban environments, since street calls are specifically developed and heard in the context of the city. Investigating...

  15. Interchain tube pressure effect in the flow dynamics of bi-disperse polymer melts

    DEFF Research Database (Denmark)

    Rasmussen, Henrik K.

    2015-01-01

    The constitutive equation as reported by Rasmussen and Huang (Rheologica Acta 53:199–208, 2014b), explaining the flow dynamics of oligomer (containing a least two Kuhn step)-diluted narrow molecular weight-distributed polymers were extended to general bi-disperse polymer melt system. It was assumed...... that the Rouse time of a particular polymer chain is dependent on the total number of Kuhn steps of the polymers in direct contact with the considered polymer chain. This number of Kuhn steps is proportional to the weight average molecular weight, M w , replacing the involved molecular weight in the equation......:453–476, 2006) and polyisoprene systems as reported by Read et al. (J Rheol 56:823–873, 2012) were within quantitatively agreement with the derived model. This included both startup of extension as well as shear flow. One exception was observed. In the most diluted polyisoprene blend, the measured extensional...

  16. Cerebral water and ion balance remains stable when humans are exposed to acute hypoxic exercise

    DEFF Research Database (Denmark)

    Avnstorp, Magnus B; Rasmussen, Peter; Brassard, Patrice

    2015-01-01

    both circumstances. No cerebral net exchange of Na(+) or K(+) was evident. Likewise, no significant net-exchange of water over the brain was demonstrated and the arterial and jugular venous hemoglobin concentrations were similar. CONCLUSION: Challenging exercise in hypoxia for 30 min affected muscle......Avnstorp, Magnus B., Peter Rasmussen, Patrice Brassard, Thomas Seifert, Morten Overgaard, Peter Krustrup, Niels H. Secher, and Nikolai B. Nordsborg. Cerebral water and ion balance remains stable when humans are exposed to acute hypoxic exercise. High Alt Med Biol 16:000-000, 2015.-Background......: Intense physical activity increases the prevalence of acute mountain sickness (AMS) that can occur within 10 h after ascent to altitudes above 1500 m and is likely related to development of cerebral edema. This study evaluated whether disturbed cerebral water and ion homeostasis can be detected when...

  17. Voluntary simulation workshops in nursing education

    DEFF Research Database (Denmark)

    Selberg, Hanne; Nielsen, Mette Elisabeth

    2012-01-01

    the students’ decision to drop out (Jensen et al. 2008). Within the past year our faculty has conducted several projects with the aim of integrating simulation into the curriculum. Furthermore, voluntary simulation workshop has been carried out as an additional offer in the nursing education. The purpose has...... were conducted with participation of 118 students in total from different levels of the nursing education. The workshops focused on both hands-on skills, communicative and teamwork skills and attention was continuously put on combining theory and practice. A questionnaire using a 10 point scale (1......Voluntary simulation workshops in nursing education Hanne Selberg1, Mette Elisabeth Nielsen1, Mette Wenzel Horsted2, Karen Bertelsen2, Marianne Linnet Rasmussen2,Rikke Lohmann Panton3, Copenhagen, Mette Kjeldal Jensen4 Background Changes in nursing education in Denmark towards an academic approach...

  18. Probabilistic models for structured sparsity

    DEFF Research Database (Denmark)

    Andersen, Michael Riis

    and to derive efficient inference algorithms for these distributions. The work explores a class of models that uses Gaussian processes (Rasmussen and Williams, 2006) as a latent representation of the structure of sparsity patterns. This representation allows prior knowledge of the structure of the sparsity...... patterns to be encoded using generic covariance functions through the Gaussian process. This thesis focuses on two specific instances of ill-posed problems: linear inverse problems and time-varying covariance estimation. The first part of the thesis deals with probabilistic methods for finding structured...... sparse solutions to linear inverse problems. In this part, the sparsity promoting prior known as the spike-and-slab prior (Mitchell and Beauchamp, 1988) is generalized to the structured sparsity setting. An expectation propagation algorithm is derived for approximate posterior inference. The proposed...

  19. The status of taxonomy and venom in sea snakes

    DEFF Research Database (Denmark)

    Redsted Rasmussen, Arne; Sanders, Kate L.

    2017-01-01

    The status of taxonomy and venom in sea snakesArne R Rasmussen1, Kate L Sanders21 The Royal Danish Academy of Fine Arts, School of Architecture, Design & Conservation, Copenhagen, Denmark2 School of Earth and Environmental Sciences, University of Adelaide, Adelaide, South Australia 5000, Australia......Sea snakes form two aquatic groups of snakes with a flat vertically paddle-form tail (sea kraits and viviparous sea snakes). Sea snakes belong to the same family Elapidae, which also includes the terrestrial mambas, cobra, kraits, taipan and brown snake. All elapids are characterized by the anterior position...... of the poison-fangs on the maxillary bone (proteroglyphous). Globally there are some 70 species of sea snake found in the tropical and subtropical waters of the Indian Ocean and the Pacific Ocean. Most species are found in the Indo-Malayan Archipelago, the China Sea, Indonesia, and the Australian region...

  20. Long-term outcomes of hemispheric disconnection in pediatric patients with intractable epilepsy.

    Science.gov (United States)

    Lee, Yun-Jeong; Kim, Eun-Hee; Yum, Mi-Sun; Lee, Jung Kyo; Hong, Seokho; Ko, Tae-Sung

    2014-04-01

    Hemispherectomy reportedly produces remarkable results in terms of seizure outcome and quality of life for medically intractable hemispheric epilepsy in children. We reviewed the neuroradiologic findings, pathologic findings, epilepsy characteristics, and clinical long-term outcomes in pediatric patients following a hemispheric disconnection. We retrospectively studied 12 children (8 males) who underwent a hemispherectomy at Asan Medical Center between 1997 and 2005. Clinical, EEG, neuroradiological, and surgical data were collected. Long-term outcomes for seizure, motor functions, and cognitive functions were evaluated at a mean follow-up of 12.7 years (range, 7.6-16.2 years) after surgery. The mean age at epilepsy onset was 3.0 years (range, 0-7.6 years). The following epilepsy syndromes were identified in our cohort: focal symptomatic epilepsy (n=8), West syndrome (n=3), and Rasmussen's syndrome (n=1). Postoperative histopathology of our study patients revealed malformation of cortical development (n=7), encephalomalacia as a sequela of infarction or trauma (n=3), Sturge-Weber syndrome (n=1), and Rasmussen's encephalitis (n=1). The mean age at surgery was 6.5 years (range, 0.8-12.3 years). Anatomical or functional hemispherectomy was performed in 8 patients, and hemispherotomy was performed in 4 patients. Eight of our 12 children (66.7%) were seizure-free, but 3 patients with perioperative complications showed persistent seizure. Although all patients had preoperative hemiparesis and developmental delay, none had additional motor or cognitive deficits after surgery, and most achieved independent walking and improvement in daily activities. The long-term clinical outcomes of hemispherectomy in children with intractable hemispheric epilepsy are good when careful patient selection and skilled surgical approaches are applied.

  1. Pseudopollen in Dendrobium unicum Seidenf. (Orchidaceae): Reward or Deception?

    Science.gov (United States)

    DAVIES, K. L.; TURNER, M. P.

    2004-01-01

    • Background and Aims In 1987, Kjellsson and Rasmussen described the labellar trichomes of Dendrobium unicum Seidenf. and proposed that these hairs function as pseudopollen. Pseudopollen is a mealy material that superficially resembles pollen, is usually laden with food substances and is formed when labellar hairs either fragment into individual cells or become detached from the labellum. However, the trichomes of D. unicum are very different from pseudopollen‐forming hairs found in other orchid genera such as Maxillaria and Polystachya. Moreover, Kjellsson and Rasmussen were unable to demonstrate the presence of food substances within these trichomes and argued that even in the absence of food substances, the hairs, in that they superficially resemble pollen, can still attract insects by deceit. The aim of this paper is to investigate whether the labellar trichomes of D. unicum contain food reserves and thus reward potential pollinators or whether they are devoid of foods and attract insects solely by mimicry. • Methods Light microscopy, histochemistry and transmission electron microscopy. • Key Results Dendrobium unicum produces pseudopollen. Pseudopollen here, however, differs from that previously described for other orchid genera in that the pseudopollen‐forming trichomes consist of a stalk cell and a ‘head’ of component cells that separate at maturity, in contrast to Maxillaria and some Polystachya spp. where pseudopollen is formed by the fragmentation of moniliform hairs. Moreover, the pseudopollen of Maxillaria and Polystachya largely contains protein, whereas in D. unicum the main food substance is starch. • Conclusions Flowers of D. unicum, rather than attracting insects solely by deceit may also reward potential pollinators. PMID:15159216

  2. A systemic analysis of South Korea Sewol ferry accident - Striking a balance between learning and accountability.

    Science.gov (United States)

    Kee, Dohyung; Jun, Gyuchan Thomas; Waterson, Patrick; Haslam, Roger

    2017-03-01

    The South Korea Sewol ferry accident in April 2014 claimed the lives of over 300 passengers and led to criminal charges of 399 personnel concerned including imprisonment of 154 of them as of Oct 2014. Blame and punishment culture can be prevalent in a more hierarchical society like South Korea as shown in the aftermath of this disaster. This study aims to analyse the South Korea ferry accident using Rasmussen's risk management framework and the associated AcciMap technique and to propose recommendations drawn from an AcciMap-based focus group with systems safety experts. The data for the accident analysis were collected mainly from an interim investigation report by the Board of Audit and Inspection of Korea and major South Korean and foreign newspapers. The analysis showed that the accident was attributed to many contributing factors arising from front-line operators, management, regulators and government. It also showed how the multiple factors including economic, social and political pressures and individual workload contributed to the accident and how they affected each other. This AcciMap was presented to 27 safety researchers and experts at 'the legacy of Jens Rasmussen' symposium adjunct to ODAM2014. Their recommendations were captured through a focus group. The four main recommendations include forgive (no blame and punishment on individuals), analyse (socio-technical system-based), learn (from why things do not go wrong) and change (bottom-up safety culture and safety system management). The findings offer important insights into how this type of accident should be understood, analysed and the subsequent response. Copyright © 2016 Elsevier Ltd. All rights reserved.

  3. The intersectoral linkage effects in Turkish economy: an application of static Leontief model

    Directory of Open Access Journals (Sweden)

    Gürkan Yay Gülsün

    2009-01-01

    Full Text Available In this study, the leading activities of Turkish Economy whose changes in their structure of production, value-added and employment are interrelated with the other activities of the economy, are found by using the input-output model which is presented and called as an 'Application of the General Equilibrium Theory' by Leontief. For this purpose; firstly theoretical foundations of the input-output model are examined. After that, 59 activities of the 2002 Input-Output Table of the Turkish Economy are aggregated at 52 sectors and classified into three categories as Ricardo Sectors, High-Technology Sectors and Heckscher-Ohlin Sectors like Dasgupta and Chakraborty did for the Indian Economy in 2005. Then, the leading, key or strong activities of the economy that are more interrelated with other activities are calculated and found by the Static Leontief Model which is used by the Traditional Methods as the techniques to calculate the linkage effects like Chenery-Watanabe and Rasmussen methods to determine the sectors having the highest priority at investment policies according to the Hirschmanian Unbalanced Growth Model. As a result of the interpretation of Leontief Model, using the traditional methods of Chenery-Watanabe and Rasmussen while calculating the linkage effects rather than the hypothesis extraction methods like Strassert's Original Extraction Method, Cella's Extraction Method, Sonis' Pure Linkage Method and Dietzenbacher and Van der Linden's Method or a SAM (Social Accounting Method model which does not omit the income generating process (distributing income among primary factors and households as a result of production of a sector, in Turkey, the Heckscher-Ohlin Sectors mostly seen in the manufacturing industry which Kaldor refers as the engine of growth, are stronger than the other sectors.

  4. The 2009 ESA/Danish Mars Simulation Wind Tunnel Facility

    Science.gov (United States)

    Nornberg, P.; Merrison, J. P.; Gunnlaugsson, H. P.

    2009-04-01

    Simulation of the dynamic environment in immediate proximity to the surface of Mars requires access to simulation facilities which can reproduce the atmospheric properties (pressure, temperature, gas composition, UV-VIS light conditions, wind flow etc.). It also requires access to analogue Martian surface material (soil and dust). Simulations can be carried out in a wind tunnel placed in a tank which can be pumped out, like the 400 mm Ø, 1500 mm long wind tunnel that has operated in the Mars Simulation Laboratory at University of Aarhus, Denmark since 2000 (1). A wide range of applications have taken place, from development, test and calibration of instruments, over tests of solar panels, and aerodynamic studies of granular transport to studies of physical properties of dust materials such as grain electrification, aggregation and magnetic properties (2,3). The Salten Skov I analogue (4) and other Martian regolits and dust analogues have been used in the wind tunnel experiments. With the view to future instrument development, solar panel optimization and future research on Martian surface processes a new ESA supported wind tunnel has been constructed at University of Aarhus, Denmark and is now under building. This wind tunnel will have a cross section of close to 1 x 2 m and be able to reach a wind speed of close to 30 m/s under Martian pressure conditions and with samples cooled down to Martian temperatures. The facility is planned to be finally tested and ready for use in July 2009. ESA, ExoMars use of this facility will have priority. However, research projects in collaboration with external users will also be welcome in the future. Later this year information on access possibilities will be announced at the Mars Simulation Laboratory home page: www.marslab.dk. References: (1) Merrison, J., Bertelsen, P., Frandsen, C., Gunnlaugsson, H.P., Knudsen, J.M., Madsen, M.B., Mossin, L., Nielsen, J., Nørnberg, P., Rasmussen, K.R., Uggerhøj, E. and Weyer, G. 2002

  5. Causas Históricas que justificaron la cirugía de las Epilepsias.

    Directory of Open Access Journals (Sweden)

    Jaime Fandiño-Franky

    2011-10-01

    Full Text Available

    RESUMEN

    Presentamos las épocas, diseñadas por nosotros, que marcaron el desarrollo de la cirugía de las epilepsias, haciendo énfasis en las realizaciones de los científicos principales como Hughlings. Jackson, Horsley, Penfield, Rasmussen, Frazer, entre otros. También hacemos alusión a los adelantos tecnológicos que marcaron hitos en estas etapas de desarrollo, como la Escanografía, el EEG y la Resonancia Magnética. Se presenta una historia de la cirugía de las epilepsias desde 1986 hasta la fecha, diviéndola por períodos marcados por la aparición de tecnologías fundamentales. Así también se describe la historia de técnicas quirúrgicas y aspectos fundamentales para la escogencia de los pacientes que ya va siendo clásica. También se dan datos biográficos de algunos autores que han marcado hitos en el tema que nos ocupa.

    Palabras clave: Cirugía de epilepsia, Historia Técnicas.

    ABSTRACT

    Historic reasons for justification of epilepsy surgery. 

    Some important historical remarks on development of epilepsy surgery are presented. Justification for using of these procedures in human beings and biographical notes of most important scientists in this field (Jackson, Horsley, Frazer, Krause, Penfield, Rasmussen and others, are emphazised. Mention is made of milestone technological developments of these times (CT Scan, EEG, MRI. We divide epilepsy surgery in periods of time, as new diagnostic and surgical techniques were appearing. Different surgical approachs for epilepsy surgery are described,also with inclusion of biographical sketches.

    Key words: Epilepsy surgery, history, techniques.

  6. Neocortical GABA release at high intracellular sodium and low extracellular calcium: an anti-seizure mechanism.

    Science.gov (United States)

    Rassner, Michael P; Moser, Andreas; Follo, Marie; Joseph, Kevin; van Velthoven-Wurster, Vera; Feuerstein, Thomas J

    2016-04-01

    In epilepsy, the GABA and glutamate balance may be disrupted and a transient decrease in extracellular calcium occurs before and during a seizure. Flow Cytometry based fluorescence activated particle sorting experiments quantified synaptosomes from human neocortical tissue, from both epileptic and non-epileptic patients (27.7% vs. 36.9% GABAergic synaptosomes, respectively). Transporter-mediated release of GABA in human and rat neocortical synaptosomes was measured using the superfusion technique for the measurement of endogenous GABA. GABA release was evoked by either a sodium channel activator or a sodium/potassium-ATPase inhibitor when exocytosis was possible or prevented, and when the sodium/calcium exchanger was active or inhibited. The transporter-mediated release of GABA is because of elevated intracellular sodium. A reduction in the extracellular calcium increased this release (in both non-epileptic and epileptic, except Rasmussen encephalitis, synaptosomes). The inverse was seen during calcium doubling. In humans, GABA release was not affected by exocytosis inhibition, that is, it was solely transporter-mediated. However, in rat synaptosomes, an increase in GABA release at zero calcium was only exhibited when the exocytosis was prevented. The absence of calcium amplified the sodium/calcium exchanger activity, leading to elevated intracellular sodium, which, together with the stimulation-evoked intracellular sodium increment, enhanced GABA transporter reversal. Sodium/calcium exchange inhibitors diminished GABA release. Thus, an important seizure-induced extracellular calcium reduction might trigger a transporter- and sodium/calcium exchanger-related anti-seizure mechanism by augmenting transporter-mediated GABA release, a mechanism absent in rats. Uniquely, the additional increase in GABA release because of calcium-withdrawal dwindled during the course of illness in Rasmussen encephalitis. Seizures cause high Na(+) influx through action potentials. A

  7. Elasto-plastic hardening models adjustment to ferritic, austenitic and austenoferritic Rebar; Ajuste de los aceros corrugados ferríticos, austeníticos y austenoferríticos a los modelos de endurecimiento elastoplástico por deformación

    Energy Technology Data Exchange (ETDEWEB)

    Hortigóna, B.; Gallardo, J.M.; Nieto-García, E.J.; López, J.A.

    2017-09-01

    The elastoplastic behaviour of steel used for structural member fabrication has received attention to facilitate a mechanical-resistant design. New Zealand and South African standards have adopted various theoretical approaches to describe such behaviour in stainless steels. With respect to the building industry, describing the tensile behaviour of steel rebar used to produce reinforced concrete structures is of interest. Differences compared with the homogenous material described in the above mentioned standards and related literatures are discussed in this paper. Specifically, the presence of ribs and the TEMPCORE® technology used to produce carbon steel rebar may alter the elastoplastic model. Carbon steel rebar is shown to fit a Hollomon model giving hardening exponent values on the order of 0.17. Austenitic stainless steel rebar behaviour is better described using a modified Rasmussen model with a free fitted exponent of 6. Duplex stainless steel shows a poor fit to any previous model. [Spanish] Uno de los principales factores tenidos en cuenta en la fabricación de aceros estructurales es su comportamiento durante la fase elastoplástica o de endurecimiento por deformación. Normas neozelandesas y sudafricanas plantean diversas aproximaciones teóricas para describir dicho comportamiento en el caso de los aceros inoxidables. En el campo de la construcción resulta de interés la descripción del comportamiento tenso-deformacional de los aceros corrugados utilizados en las estructuras de hormigón armado. En este artículo se discuten los modelos planteados en las normas citadas anteriormente así como los existentes en la literatura tanto para los aceros corrugados inoxidables como para los aceros al carbono fabricados mediante el proceso denominado TEMPCORE® Los aceros TEMPCORE® analizados arrojan un valor del exponente de endurecimiento por deformación según el modelo de Hollomon de 0.17. Los aceros inoxidables austeníticos se ajustan mejor al modelo

  8. Bosquejo histórico de la Cefalometría Radiográfica Historical sketch of radiographic cephalometry

    Directory of Open Access Journals (Sweden)

    Alberto Companioni Bachá

    2008-06-01

    Full Text Available La cefalometría es un elemento importante en la conformación de una documentación ortodóncica para elaborar un diagnóstico y un plan de tratamiento adecuado. Con el descubrimiento de los rayos X, el 8 de noviembre de 1895 por Wilhhelm Conrad Roentgen, y la existencia de técnicas que precedieron a los rayos X, como la craneometría y la antropología, es que los ortodoncistas pueden contar con esta herramienta diagnóstica de inestimable valor. En el perfeccionamiento de la técnica cefalométrica y de sus análisis contemporáneos ha sido importante el concurso de diversos autores entre los que se destacan Broadbent, Bolton, Hofrath, Korkhaus, Ubaldo Carrea, De Nevreze, Paul Simon y Dreyfus, Margolis, Weingart, Thurow, Bjork, Freeman-Rasmussen, Reboul, Steiner, Andrews, Ricketts, Holdaway, McNamara, Interlandi, entre otros. Este trabajo se propone hacer un recuento de los hechos más significativos que acompañaron la evolución y desarrollo de la cefalometríaCephalometry is an important element to take into account at the time of preparing an orthodontic documentation in order to make a diagnosis and an adequate treatment plan. Thanks to the discovery of X-rays on November 8, 1895 by Wilhhelm Conrad Roentgen, and to the existence of techniques that preceded the X-rays, such as craniometry and anthropology, orthodontists may use this diagnostic tool of great value. In the improvement of the cephalometric technique and its contemporary analyses it has been important the collaboration of various authors, among whom Broadbent, Bolton, Hofrath, Korkhaus, Ubaldo Carrea, De Nevreze, Paul Simon and Dreyfus, Margolis, Weingart, Thurow, Bjork, Freeman-Rasmussen, Reboul, Steiner, Andrews, Ricketts, Holdaway, McNamara and Interlandi, stand out. This paper intends to make an account of the most significant events related to the evolution and development of cephalometry

  9. The role of climate in balancing soil production and sediment yield in New Zealand

    Science.gov (United States)

    Norton, K. P.

    2013-12-01

    New Zealand hosts some of the highest specific sediment yields on the planet reaching up to nearly 30,000 t km-2 yr-1. Sediment yields measure the export of sediment from a basin and give an indication of erosion from hillslopes. In New Zealand high sediment yields correlate with high annual precipitation and high rates of tectonic strain (Hicks et al., 1996). It is, however, unclear how soil production keeps pace with such extreme erosion. Here, this question is investigated by modelling soil production as a function of local climate parameters. Two simple models for building climate into soil production are through effective energy and mass transfer, EEMT, (Rasmussen and Tabor, 2007) and primary chemical weathering. When applied to ~30 year climate data, these models highlight the variability of potential soil production across New Zealand. Due partially to high annual rainfall, some of the fastest erosion rates on the west coast of the South Island are nearly in balance with soil production. In other regions such as the east coast of the North Island, hotspots exist where annual sediment yields exceed reasonable soil production rates such that additional mechanisms must operate to generate sediment and make up this deficit. Globally, precipitation tends to increase and temperature decreases with increasing elevation. In New Zealand, increasing elevations also roughly correlate with an increase in mean basin slope angle and the percent of a basin at >30° slopes. As a result, modelled soil production also tends to increase with increasing mean basin slope angle. This correlation occurs independent of erosion feedbacks on the modelled soil production rates. This relationship presents an intriguing scenario in which the topography of the mountain range may be maintained by climate through variations in soil production. Even with rapid modelled soil production at high precipitation rates and/or high temperatures and/or high temperatures, many basins cannot keep pace

  10. Two-year follow-up of intelligence after pediatric epilepsy surgery.

    Science.gov (United States)

    Korkman, Marit; Granström, Marja-Liisa; Kantola-Sorsa, Elisa; Gaily, Eija; Paetau, Ritva; Liukkonen, Elina; Boman, Petra-Ann; Blomstedt, Göran

    2005-09-01

    Research findings concerning cognitive effects of pediatric epilepsy surgery form an important basis for decisions about surgery. However, most follow-up studies have been of limited duration. In this study, a 2-year follow-up of intelligence was undertaken. Risk factors were analyzed. Included were 38 patients aged 3 to 17 years. Surgery was left in 19 patients and right in 19 patients. Types of surgery included temporal lobe resection (n = 23), extratemporal or multilobar resection (n = 8), and hemispherectomy (n = 7). The Wechsler Scales of Intelligence were administered presurgically, 6 months postsurgically, and 2 years postsurgically. No significant change in verbal or performance intelligence quotient (IQ) was demonstrated on a group level. Lateralization, type of surgery, age at surgery, sex, and presurgical IQ did not affect outcome. Across assessments, IQ scores of left-hemisphere patients were lower than those of right-hemisphere patients. Scores of patients in the hemispherectomy group were lower than those of the extratemporal or multilobar resection group, which were lower than the temporal lobe resection group. Scores improved significantly in six patients and deteriorated in seven. In conclusion, epilepsy surgery in children and adolescents does not, in general, have a significant impact on cognitive development in a 2-year perspective. In individual patients, poor seizure control and extensive surgery for Rasmussen's encephalitis were related to a deterioration of IQ.

  11. Imaging of the epilepsies

    Energy Technology Data Exchange (ETDEWEB)

    Urbach, H. [University of Bonn Medical Center, Department of Radiology/Neuroradiology, Bonn (Germany)

    2005-03-01

    Imaging of epilepsy patients is challenging, since epileptogenic lesions (defined as structural lesions causally related to the epilepsy syndrome) may be small and often do not change during life. Prior clinical information about the epilepsy syndrome and the semiology of the seizures is needed in order to plan the examination properly. The effort to detect an epileptogenic lesion is directed to partial (focal) epilepsy syndromes whereas - by definition - no lesion is identified in idiopathic epilepsies. Most patients with partial epilepsies suffer from mesial temporal lobe epilepsies. In these patients, 2- to 3-mm-thick T2-weighted and fluid-attenuated inversion-recovery (FLAIR) fast spin echo slices along or perpendicular to the temporal lobe length axis have the highest diagnostic efficacy. In contrast, in patients with extratemporal lobe epilepsies perpendicular FLAIR slices through the anatomic region, from which, due to clinical and EEG criteria, the seizures are likely to originate, are preferred. The imaging features of common epileptogenic lesions (hippocampal sclerosis, long-term epilepsy-associated tumours, focal cortical dysplasias, vascular malformations, encephalitis including limbic and Rasmussen's encephalitis, gyral scarring including ulegyria) are detailed in the second section of this paper. (orig.)

  12. [Long-term outcome after hemispheric disconnection].

    Science.gov (United States)

    Bulteau, C; Dorfmüller, G; Fohlen, M; Jalin, C; Oliver, M-V; Delalande, O

    2008-05-01

    Hemispheric disconnection has been largely proposed for patients with severe epilepsy associated with a congenital or acquired hemispheric cerebral pathology. The classical procedure of anatomical hemispherectomy was progressively abandoned by neurosurgeons in order to avoid postoperative complications since then hemispherotomy techniques have been developed. Globally, with hemispheric disconnection, the rate of patients becoming seizure-free has been between 50 and 80%. The factors affecting seizure control have not been completely elucidated, but several authors suggested that differences in etiology as well as the hemispheric disconnection technique used may partially explain this variability. The percentage of seizure-free patients is higher with hemispherotomy techniques and in the group of patients with Rasmussen encephalitis, Sturge-Weber syndrome, and vascular insults. Depending on overall long-term progression, there is an improvement compared to preoperative status even if children exhibit heterogenous abilities. The lowest scores are observed for motor skills but communication and socialization are relatively well-preserved and strongly related to the duration of epilepsy: the longer the duration, the lower the scores were. Neuropsychological outcome following hemispheric disconnection makes it possible to study the development of hemispheric specialization during infancy and to provide information on cognitive recovery. Cerebral reorganization has been proved to exist in motor and language recovery. Ipsilateral corticospinal pathways seem to be involved in the movement of hemiplegic limbs. Everyday language can be supported by both hemispheres, but there is an early hemispheric specialization of the left hemisphere according to metaphonologic abilities.

  13. Relevant Organizational Factors for Social Efficiency in the Road Transport Sector; Procesos Organizativos Clave para la Eficiencia Social en el Transporte por Carretera

    Energy Technology Data Exchange (ETDEWEB)

    Silla, I.; Gamero, N.

    2011-12-27

    Previous research has emphasized the need to consider the social dimension featuring organizations in order to maximize organizational efficiency (Rasmussen, 1997). In the road transport sector, previous research has focused on the relationship between human factor, stress, fatigue, and other relevant issues, and professional drivers health and safety (p.e., De Croon et al, 2004). However, research on relevant organizational factors is scarce. This study aims to examine the association between leadership and supportive climate, and employees health and safety. Moreover, the impact of stress (time pressure) was also examined because previous research has stressed its importance. This study used a sample of 486 employees from 35 different Spanish companies pertaining to the road transport sector. Findings showed time pressure to be negatively associated to employees health, job satisfaction and satisfaction with safety. Additionally, leadership was positively associated employees health, job satisfaction and satisfaction with safety. Finally, co-workers and supervisors supportive climate was positively associated with job satisfaction and negatively associated to illness. These findings have relevant practical implications for the competitiveness of road transport companies. (Author) 21 refs.

  14. The relationship of the Yale-Brown Obsessive Compulsive Scale (YBOCS) to other measures of obsessive compulsive symptoms in a nonclinical population.

    Science.gov (United States)

    Frost, R O; Steketee, G; Krause, M S; Trepanier, K L

    1995-08-01

    The Yale-Brown Obsessive Compulsive Scale (YBOCS; Goodman, Price, Rasmussen, & Mazure, 1989a) is an interview-based rating scale measuring severity of obsessive compulsive disorder (OCD). Because it is independent of the number and type of OCD symptoms and minimizes confounding with other types of symptoms, it has become the "gold standard" for assessing the outcome of behavioral and pharmacological treatments. This study was designed to further validate the YBOCS in relation to self-report measures of obsessive compulsive phenomena in a nonclinical population. Among a group of 45 female college students, the three primary YBOCS measures (obsessions, compulsions, and total score) were internally consistent and correlated moderately to strongly with self-report measures of obsessive compulsive phenomena that have been used in previous research. The compulsive subscale of the YBOCS showed the lowest correlation with self-report measures sharing only 25% of the common variance. This measure is appropriate for use with nonclinical samples and may prove superior to other instruments for detecting the presence and severity of obsessive and compulsive symptoms.

  15. Politisk smag

    DEFF Research Database (Denmark)

    Fugl, Marie; Laursen, Bent

    om klasse. Dette påvises i bogen ved hjælp af Bourdieus begreber om kapital, det sociale rum, felt, klasse, habitus og smag.  I kapitel 3 og 4 præsenteres en række resultater fra den empiriske forskning - i kapitel 3 er kvantitativ analyse i fokus, mens den kvalitative analyse står centralt i kapitel......Pierre Bourdieu anses normalt for at være ret vanskelig tilgængelig for vores elever og kursister. I Politisk smag kommer Bourdieu ned i øjenhøjde dels ved at teorien præsenteres på en overkommelig og letforståelig måde, dels ved at en række centrale undersøgelsesmetoder fra den kommercielle...... markedsføring anvendes på politisk kommunikation. "Klassesamfundet er opløst - klassekampen er slut" sagde statsminister Anders Fogh Rasmussen i åbningstalen 2003! Passer det nu? Ifølge Bourdieu disponeres en række af vore dispositioner fortsat af vores klassemæssige placering. Vælgeradfærd er også et spørgsmål...

  16. Hotplate precipitation gauge calibrations and field measurements

    Directory of Open Access Journals (Sweden)

    N. Zelasko

    2018-01-01

    Full Text Available First introduced in 2003, approximately 70 Yankee Environmental Systems (YES hotplate precipitation gauges have been purchased by researchers and operational meteorologists. A version of the YES hotplate is described in Rasmussen et al. (2011; R11. Presented here is testing of a newer version of the hotplate; this device is equipped with longwave and shortwave radiation sensors. Hotplate surface temperature, coefficients describing natural and forced convective sensible energy transfer, and radiative properties (longwave emissivity and shortwave reflectance are reported for two of the new-version YES hotplates. These parameters are applied in a new algorithm and are used to derive liquid-equivalent accumulations (snowfall and rainfall, and these accumulations are compared to values derived by the internal algorithm used in the YES hotplates (hotplate-derived accumulations. In contrast with R11, the new algorithm accounts for radiative terms in a hotplate's energy budget, applies an energy conversion factor which does not differ from a theoretical energy conversion factor, and applies a surface area that is correct for the YES hotplate. Radiative effects are shown to be relatively unimportant for the precipitation events analyzed. In addition, this work documents a 10 % difference between the hotplate-derived and new-algorithm-derived accumulations. This difference seems consistent with R11's application of a hotplate surface area that deviates from the actual surface area of the YES hotplate and with R11's recommendation for an energy conversion factor that differs from that calculated using thermodynamic theory.

  17. Nutrients for the aging eye

    Directory of Open Access Journals (Sweden)

    Rasmussen HM

    2013-06-01

    Full Text Available Helen M Rasmussen,1 Elizabeth J Johnson2 1Educational Studies, Lesley University, Cambridge, MA, USA; 2Carotenoid and Health Laboratory, Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA Abstract: The incidence of age-related eye diseases is expected to rise with the aging of the population. Oxidation and inflammation are implicated in the etiology of these diseases. There is evidence that dietary antioxidants and anti-inflammatories may provide benefit in decreasing the risk of age-related eye disease. Nutrients of interest are vitamins C and E, β-carotene, zinc, lutein, zeaxanthin, and the omega-3 fatty acids eicosapentaenoic acid and docosahexaenoic acid. While a recent survey finds that among the baby boomers (45–65 years old, vision is the most important of the five senses, well over half of those surveyed were not aware of the important nutrients that play a key role in eye health. This is evident from a national survey that finds that intake of these key nutrients from dietary sources is below the recommendations or guidelines. Therefore, it is important to educate this population and to create an awareness of the nutrients and foods of particular interest in the prevention of age-related eye disease. Keywords: nutrition, aging, eye health

  18. Identification of Key Productive Sectors in the Mexican Economy

    Directory of Open Access Journals (Sweden)

    David REVILLA

    2015-03-01

    Full Text Available This article focuses on identifying what are the key sectors with high potential for drag induced investment in the Mexican economy, also characterizes the sectors according to their hierarchy, impact and degree of articulation. To achieve this the input-output matrix national 2003 was used (disaggregated into 20 sectors and 79 sub-sectors, provided by the official government agency responsible for generating statistical information, which applied the traditional method of calculation of multipliers which takes into account both relations hierarchical such as circular between the productive sectors of Rasmussen (1956. The originality of the work lies in the application of the social networks theory to determine (García, Morillas and Ramos 2005, 2008: a total effects, b immediate effects, and c mediative effects of sectors and thus have a full diagnosis of key sectors of the economy under study. In general, the findings indicate that for the promotion of growth and productive development, efforts should focus on manufacturing industries, which means to apply an active industrial policy.

  19. A participant-observer study of ergonomics in engineering design: how constraints drive design process.

    Science.gov (United States)

    Burns, C M; Vicente, K J

    2000-02-01

    Too often, ergonomics is relegated to being a "post-design" evaluation, leaving ergonomists little opportunity to make significant and important design changes. One way to start attacking this problem is to study the process of design and, in particular, ergonomics in design. This article describes the findings from a four-month long participant-observer study of the relationship between ergonomics and engineering design. The study was conducted in the context of a large, interdisciplinary project consisting of design of a control room for a nuclear power plant. It was observed that designers and ergonomists must negotiate through a changing web of constraints from many sources. The impact that these constraints had on the course of the design was documented. A model is developed based on the abstraction hierarchy (Rasmussen, 1985, IEEE Trans. Systems Man Cybernet. SMC-15, 234-243; 1990, Int. J. Ind. Ergon. 5, 5-16) which shows the interaction of conflicting goals as ergonomists and other designers attempt to solve a complex design problem. This model leads to several insights: (1) locally optimal ergonomic designs may not be globally optimal, (2) ergonomists can improve their solutions by understanding the goals of other designers, and (3) future tools to aid ergonomists must be compatible with the constraint-rich environments in which they work.

  20. Outcome of childhood-onset epilepsy from adolescence to adulthood: Transition issues.

    Science.gov (United States)

    Nabbout, R; Andrade, D M; Bahi-Buisson, N; Cross, H; Desquerre, I; Dulac, O; Granata, T; Hirsch, E; Navarro, V; Ouss, L; Pearl, P L; Schmidt, D; Thiele, E; Camfield, P R; Camfield, C S

    2017-04-01

    This is the second of three papers that summarize the second symposium on Transition in Epilepsies held in Paris in June 2016. This paper addresses the outcome for some particularly challenging childhood-onset epileptic disorders with the goal of recommending the best approach to transition. We have grouped these disorders in five categories with a few examples for each. The first group includes disorders presenting in childhood that may have late- or adult-onset epilepsy (metabolic and mitochondrial disorders). The second group includes disorders with changing problems in adulthood (tuberous sclerosis complex, Rett syndrome, Dravet syndrome, and autism). A third group includes epilepsies that change with age (Childhood Absence Epilepsy, Juvenile Myoclonic Epilepsy, West Syndrome, and Lennox-Gastaut syndrome). A fourth group consists of epilepsies that vary in symptoms and severity depending on the age of onset (autoimmune encephalitis, Rasmussen's syndrome). A fifth group has epilepsy from structural causes that are less likely to evolve in adulthood. Finally we have included a discussion about the risk of later adulthood cerebrovascular disease and dementia following childhood-onset epilepsy. A detailed knowledge of each of these disorders should assist the process of transition to be certain that attention is paid to the most important age-related symptoms and concerns. Copyright © 2016 Elsevier Inc. All rights reserved.

  1. Habitat Evaluation Procedures (HEP) Report; Burlington Bottoms, Technical Report 1993-2003.

    Energy Technology Data Exchange (ETDEWEB)

    Beilke, Susan

    1993-08-01

    Burlington Bottoms, consisting of approximately 417 acres of riparian and wetland habitat, was purchased by the Bonneville Power Administration in November 1991. The site is located approximately 1/2 mile north of the Sauvie Island Bridge (T2N R1W Sections 20, 21), and is bound on the east side by Multnomah Channel and on the west side by the Burlington Northern Railroad right-of-way and U.S. Highway 30 (Figures 1 and 2). Wildlife habitat values resulting from the purchase of this site will contribute toward the goal of mitigating for habitat lost as outlined in the Columbia and Willamette River Basin's Fish and Wildlife Program and Amendments. Under this Program, mitigation goals were developed as a result of the loss of wildlife habitat due to the development and operation of Federal hydro-electric facilities in the Columbia and Willamette River Basins. In 1993, an interdisciplinary team was formed to develop and implement quantitative Habitat Evaluation Procedures (HEP) to document the value of various habitats at Burlington Bottoms. Results of the HEP will be used to: (1) determine the current status and habitat enhancement potential of the site consistent with wildlife mitigation goals and objectives; and (2) develop a management plan for the area. HEP participants included; Charlie Craig, BPA; Pat Wright, Larry Rasmussen, and Ron Garst, U. S. Fish and Wildlife Service; John Christy, The Nature Conservancy; and Doug Cottam, Sue Beilke, and Brad Rawls, Oregon Department of Fish and Wildlife.

  2. Do not blame the driver: a systems analysis of the causes of road freight crashes.

    Science.gov (United States)

    Newnam, Sharon; Goode, Natassia

    2015-03-01

    Although many have advocated a systems approach in road transportation, this view has not meaningfully penetrated road safety research, practice or policy. In this study, a systems theory-based approach, Rasmussens's (1997) risk management framework and associated Accimap technique, is applied to the analysis of road freight transportation crashes. Twenty-seven highway crash investigation reports were downloaded from the National Transport Safety Bureau website. Thematic analysis was used to identify the complex system of contributory factors, and relationships, identified within the reports. The Accimap technique was then used to represent the linkages and dependencies within and across system levels in the road freight transportation industry and to identify common factors and interactions across multiple crashes. The results demonstrate how a systems approach can increase knowledge in this safety critical domain, while the findings can be used to guide prevention efforts and the development of system-based investigation processes for the heavy vehicle industry. A research agenda for developing an investigation technique to better support the application of the Accimap technique by practitioners in road freight transportation industry is proposed. Copyright © 2015 Elsevier Ltd. All rights reserved.

  3. Energi E2 A/S - ICAT collaboration 1999-2002[Interdisciplinary researd Centre for Catalysis

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2002-04-01

    This report describes the projects funded by E2 and Elkraft System in the start-up phase of ICAT, DTU in the period 1999-2002. Three projects have been funded during that period. Two of the projects, part I and II, are specifically dealing with the cleaning of flue gasses, while part III is dealing with establishing equipment at ICAT for parallel screening of potential alloy catalysts, which can be used for fuel cell technology. The exact amount of funding spent on the respective projects is described in the enclosed economy section. The results obtained under each of three projects are described in the foliowing three partial reports. The report have been prepared by the post-docs directly involved in the individual projects, namely Stefan Hagen, Stephen Masters, Soeren Birk Rasmussen, and Martin Johansson. It is the policy of ICAT to have a significant fraction of foreigners in the staff and therefore a considerably fraction of this report have been prepared in English. Beyond the four main authors a number of other ICAT staff members have been involved at different levels. For details we refer to the headings of the individual reports. (au)

  4. Hemispherectomy: a basis for mental development in children with epilepsy.

    Science.gov (United States)

    van Schooneveld, Monique M J; Jennekens-Schinkel, Aag; van Rijen, Peter C; Braun, Kees P J; van Nieuwenhuizen, Onno

    2011-03-01

    To detect change in mental development or intelligence over two years following hemispherectomy in children with pharmacologically intractable epilepsy. Seventeen infants and preschoolers (median age at epilepsy onset of 0.0 years and at hemispherectomy 1.5 years; epilepsy duration of 0.2-2.6 years) and 12 older children (median age at onset of 1.0 year and at hemispherectomy 8.3 years; epilepsy duration of 1.1-11.7 years) with pharmacologically intractable seizures due to developmental, acquired or progressive pathology. Prospective study with consecutive inclusion of children, fixed assessment intervals (shortly before and 6, 12 and 24 months after hemispherectomy) and assessment using developmental scales and intelligence scales. Dependent variables included mental developmental index (MDI), mental age (MA) and mental developmental delay (MDD) in younger children and intelligence quotient (IQ) in older children. Mental development had arrested or deteriorated prior to hemispherectomy in 14 children (82%) assessed with developmental scales. In 14 children, it was not possible to more precisely determine MDI than "below the lowest MDI that the test manual provided" either before or after hemispherectomy. MA, however, increased in 16 children. Overall, IQ changed negligibly over two years after hemispherectomy, although an individual approach revealed variability. Children with Rasmussen encephalitis did not recover from the significant presurgical deterioration of intelligence. Removal of the affected hemisphere enables epileptic children, even those with severe mental delay, to further develop mentally.

  5. The Miocene “Pteropod event” in the SW part of the Central Paratethys (Medvednica Mt., northern Croatia

    Directory of Open Access Journals (Sweden)

    Bošnjak Marija

    2017-08-01

    Full Text Available Deep marine Miocene deposits exposed sporadically in the Medvednica Mt. (northern Croatia comprise pelagic organisms such as coccolithophores, planktic foraminifera and pteropods. The pteropod fauna from yellow marls at the Vejalnica locality (central part of Medvednica Mt. encompasses abundant specimens of Vaginella austriaca Kittl, 1886, accompanied with scarce Clio fallauxi (Kittl, 1886. Calcareous nannoplankton points to the presence of NN5 nannozone at this locality. Highly fossiliferous grey marls at the Marija Bistrica locality (north-eastern area of Medvednica Mt. comprise limacinid pteropods: Limacina valvatina (Reuss, 1867, L. gramensis (Rasmussen, 1968 and Limacina sp. Late Badenian (NN5 to NN6 nannozone age of these marls is presumed on the basis of coccolithophores. Most of the determined pteropods on species level, except V. austriaca have been found and described from this region for the first time. New pteropod records from Croatia point to two pteropod horizons coinciding with the Badenian marine transgressions in Central Paratethys. These pteropod assemblages confirm the existence of W–E marine connection (“Transtethyan Trench Corridor” during the Badenian NN5 nannozone. Limacinids point to the possible immigration of the “North Sea fauna” through a northern European marine passage during the Late Badenian (end of NN5-beginning of NN6 zone, as previously presumed by some other authors.

  6. The Toxicology of Carbon Nanotubes

    Science.gov (United States)

    Donaldson, Ken; Poland, Craig; Duffin, Rodger; Bonner, James

    2012-06-01

    1. Carbon nanotube structure, synthesis and applications C. Singh and W. Song; 2. The aerodynamic behaviour and pulmonary deposition of carbon nanotubes A. Buckley, R. Smith and R Maynard; 3. Utilising the concept of the biologically effective dose to define the particle and fibre hazards of carbon nanotubes K. Donaldson, R. Duffin, F. Murphy and C. Poland; 4. CNT, biopersistence and the fibre paradigm D. Warheit and M. DeLorme; 5. Length-dependent retention of fibres in the pleural space C. Poland, F. Murphy and K. Donaldson; 6. Experimental carcinogenicity of carbon nanotubes in the context of other fibres K. Unfried; 7. Fate and effects of carbon nanotubes following inhalation J. Ryman-Rasmussen, M. Andersen and J. Bonner; 8. Responses to pulmonary exposure to carbon nanotubes V. Castranova and R. Mercer; 9. Genotoxicity of carbon nanotubes R. Schins, C. Albrecht, K. Gerloff and D. van Berlo; 10. Carbon nanotube-cellular interactions; macrophages, epithelial and mesothelial cells V. Stone, M. Boyles, A. Kermanizadeh, J. Varet and H. Johnston; 11. Systemic health effects of carbon nanotubes following inhalation J. McDonald; 12. Dosimetry and metrology of carbon nanotubes L. Tran, L. MacCalman and R. Aitken; Index.

  7. Musikplanlægning i Danmarks Radio - et interview med to musikansvarlige

    Directory of Open Access Journals (Sweden)

    Henrik Dahl

    1992-08-01

    Full Text Available Danmarks Radio er en væsentlig faktor i det danske musikliv i dag. Musikindustrien får sine potentielle hits præsenteret og den levende musik kommer ud via transmissionsvognene. DR har tre orkestre og 2 kor og producerer selv musik af høj kvalitet. Der er tale om et kredsløb - eller fødekæde om man vil - hvor radioen indgår som distributionskanal, udstillingsvindue og formidler af både musik og diskussionen omkring den. Hvordan forvalter Danmarks Radio sin musik- og kulturpolitiske funktion? Hvem bestemmer hvad der skal spilles i radioen? Er det medarbejderne, programcheferne eller radioledelsen? Og hvem tager man hensyn til? Lyttertal? Den offentlige mening? - I dette dobbeltinterview med to chefer, Bent-Erik Rasmussen og Torben Bille, der er ansvarlige for musikken på henholdsvis P2 (undtagen Danmarkskanalen og P3, prøver vi at belyse de overvejelser der ligger bag den seneste kanalomlægning og den daglige styring af danskernes musikoplevelser.

  8. Spoken language outcomes after hemispherectomy: factoring in etiology.

    Science.gov (United States)

    Curtiss, S; de Bode, S; Mathern, G W

    2001-12-01

    We analyzed postsurgery linguistic outcomes of 43 hemispherectomy patients operated on at UCLA. We rated spoken language (Spoken Language Rank, SLR) on a scale from 0 (no language) to 6 (mature grammar) and examined the effects of side of resection/damage, age at surgery/seizure onset, seizure control postsurgery, and etiology on language development. Etiology was defined as developmental (cortical dysplasia and prenatal stroke) and acquired pathology (Rasmussen's encephalitis and postnatal stroke). We found that clinical variables were predictive of language outcomes only when they were considered within distinct etiology groups. Specifically, children with developmental etiologies had lower SLRs than those with acquired pathologies (p =.0006); age factors correlated positively with higher SLRs only for children with acquired etiologies (p =.0006); right-sided resections led to higher SLRs only for the acquired group (p =.0008); and postsurgery seizure control correlated positively with SLR only for those with developmental etiologies (p =.0047). We argue that the variables considered are not independent predictors of spoken language outcome posthemispherectomy but should be viewed instead as characteristics of etiology. Copyright 2001 Elsevier Science.

  9. In vivo deposition of ultrafine aerosols in human nasal and oral airways

    Energy Technology Data Exchange (ETDEWEB)

    Yeh, Hsu-Chi; Swift, D.L. [John Hopkins Univ., Baltimore, MD (United States); Simpson, S.Q. [Univ. of New Mexico, Albuquerque, NM (United States)] [and others

    1995-12-01

    The extrathoracic airways, including the nasal passage, oral passage, pharynx, and larynx, are the first targets for inhaled particles and provide an important defense for the lung. Understanding the deposition efficiency of the nasal and oral passages is therefore crucial for assessing doses of inhaled particles to the extrathoracic airways and the lung. Significant inter-subject variability in nasal deposition has been shown in recent studies by Rasmussen, T.R. et al, using 2.6 {mu}m particles in 10 human subjects and in our preliminary studies using 0.004-0.15 {mu}m particles in four adult volunteers. No oral deposition was reported in either of these studies. Reasons for the intersubject variations have been frequently attributed to the geometry of the nasal passages. The aims of the present study were to measure in vivo the nasal airway dimensions and the deposition of ultrafine aerosols in both the nasal and oral passages, and to determine the relationship between nasal airway dimensions and aerosol deposition. A statistical procedure incorporated with the diffusion theory was used to model the dimensional features of the nasal airways which may be responsible for the biological variability in particle deposition. In summary, we have correlated deposition of particles in the size range of 0.004 to 0.15 {mu}m with the nasal dimensions of each subject.

  10. fMRI after Phalloplasty with Nerve Anastomosis in a Trans-Man Patient

    Science.gov (United States)

    Carlsson, Åsa; Jönsson, Emma H.; Jönsson, Lars; Thorarinsson, Andri; Lidén, Mattias; Selvaggi, Gennaro

    2017-01-01

    Summary: We report on a case of a trans-man patient, who underwent penile reconstruction with the use of a radial forearm flap, urethroplasty, vaginectomy and scrotoplasty, insertion of testicle implants, and penile erection implants, similar to previously described methods. One of the requirements for an ideal phalloplasty is the preservation of erogenous sensitivity, which is often demanded by the patients for fulfilling their sexual well-being. For the first time known to us, we use a functional magnetic resonance imaging following radial forearm flap phalloplasty with nerve anastomosis to assess the cortical activation after clitoral stimulation. The patient was poked with a plastic pen on the neophallus and the groin. Regular block design with T1 and BOLD-T2* images were used. The results contradict the classic Penfield and Rasmussen homunculus, that is, the activations in the primary somatosensory cortex (S1) were bilateral with a left-sided dominance in the lateral parts of the medial postcentral gyrus (same region as the groin), and no activations were observed in the mesial parts of the postcentral gyrus. We also reported bilateral activations with a left-sided dominance in the secondary somatosensory cortex (S2) and near Broca’s area at the sylvian fissure just posterior to ramus ascendens. Our findings are similar to previous studies reporting on imaging related to genital sensitivity. PMID:28740768

  11. Ole Søndergaards skriftdesign

    DEFF Research Database (Denmark)

    Ejlers, Steen Erik

    2005-01-01

    Grafikeren Ole Søndergaard (f. 1937) er oprindeligt uddannet som skiltemaler. Senere blev han elev af navnkundige skriftformgiver, Kunstakademiets første designprofessor, arkitekturen Gunnar Biilmann Petersen. I 1970'erne etablerede Ole Søndergaard, efter nogle år som medarbejder på Naur Klints...... tegnestue, egen tegnestue i Helsingør. Tegnestuen har i årenes løb stået for mangfoldige grafiske arbejder, hvor Ole Søndergaard ofte selv har tegnet de anvendte logo- og skilteskrifter. Skriftfamilien FF Signa, der fra 2000 er blevet udgivet på FontShop International, er Søndergaards første komplette...... digitale skriftfamilie - med mangfoldige anvendelsemuligheder. Forud ligger adskillige års arbejde, bl.a. støttet af Statens Kunstfond. Artiklen beskriver Biilmanns skole, Ole Søndergaards "før-digitale" alfabeter til bl.a. Helsingør Kommune og Knud Rasmussen-monumentet (på Strandvejen ved Klampenborg nord...

  12. Collaboration between student art teachers and communication and digital media students promoting subject specific didactics in digital visual learning design

    DEFF Research Database (Denmark)

    Skov, Kirsten; Buhl, Mie

    of learning designs and digital media in visual arts education (Peppler 2010, Rasmussen 2015, Buhl & Ejsing-Duun, 2015; Buhl, 2016). Methodology The choice of empirical design was based on the purpose of involving the future users in developing a visual learning design, and thereby drawing on visual art....... p. 26-40 (14 s.) Buhl, M. (2016) Theory-generating practice. Proposing a principle for learning design. Læring og Medier (LOM), Vol. 9, No. 15, 2016, p. 1-21 Buhl, M. & Ejsing-Duun (2015) Blended learning promoting new developments for Nordic master programs in visual studies and art education, ECEL...... Proceedings, Hatfield Buhl, M. & Flensborg (2011). Visuel kulturpædagogik, København: Hans Reitzels Forlag Peppler, K. (2010). Media arts: Arts education for a digital age. Teachers College Record, vol 112, nr. 8, p. 2118-2153 http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.700.7662&rep=rep1&type=pdf...

  13. Cognitive work analysis: An influential legacy extending beyond human factors and engineering.

    Science.gov (United States)

    Naikar, Neelam

    2017-03-01

    Jens Rasmussen's multifaceted legacy includes cognitive work analysis (CWA), a framework for the analysis, design, and evaluation of complex sociotechnical systems. After considering the framework's origins, this paper reviews its progress, predictably covering experimental research on ecological interface design, case studies of the application of CWA to human factors and engineering problems in industry, and methods and modelling tools for CWA. Emphasis is placed, however, on studying the nexus between some of the recent results obtained with CWA and the original field studies of human problem-solving that motivated the framework's development. Of particular interest is a case study of the use of CWA for military doctrine development, a problem commonly regarded as lying outside the fields of human factors and engineering. It is concluded that the value of CWA, even for such diverse problems, is likely to result from its conceptual grounding in empirical observations of patterns of human reasoning in complex systems. Crown Copyright © 2016. Published by Elsevier Ltd. All rights reserved.

  14. Análise locacional e impactos econômicos do segmento sucroalcooleiro em Mato Grosso

    Directory of Open Access Journals (Sweden)

    Wladimir Colman de Azevedo Junior

    2012-01-01

    Full Text Available O cultivo da cana-de-açúcar tem se intensificado na região central do Brasil e oestado de Mato Grosso tornou-se um dos principais produtores de etanol e açúcardo país. Entender o comportamento desta cadeia, considerando a caracterizaçãoeconômica espacial do cultivo e os efeitos multiplicadores sobre a economia éimportante para sabermos a magnitude de cada atividade e sua importância para odesenvolvimento local. Para mensurar os efeitos multiplicadores foi utilizada a MatrizInsumo-Produto (MIP de Mato Grosso, atualizada para o ano de 2007, que permitiua construção dos índices de ligações Rasmussen-Hirschman e dos efeitosmultiplicadores. A identificação da concentração territorial do cultivo da cana-deaçúcarfoi possível por meio do Índice de Concentração Normalizado (ICN, queutiliza dados do PIB e do valor da produção para mapear os espaços cuja referidaatividade é tida como economicamente diferenciada. O resultado auferido reflete queo elo industrial da cadeia possui forte poder de dispersão de investimento e que em2007 se localizava em apenas 11 municípios no estado. O elo agrícola da cadeiaapresentou forte sensibilidade de dispersão e também se localiza em 11 municípiostidos como diferenciados e que por isto concentram a produção da cana em seusterritórios.Abstract The cultivation of sugar cane has intensified in the central region of Brazil andthe state of Mato Grosso has become a leading producer of ethanol and sugar in thecountry. Understanding the behavior of this chain, considering the characterization ofgrowing economic space and the multiplier effects on the economy is important toknow the magnitude of each activity and its importance for local development. Tomeasure the multiplier effects we used the input-output matrix (IPM of Mato Grosso,updated to the year 2007, which allowed the construction of indexes linksRasmussen-Hirschman and multiplier effects. The identification of

  15. Time Structure of a Mass Extinction: The Cretaceous- Tertiary Boundary

    Science.gov (United States)

    Hansen, H. J.; Rasmussen, K. L.; Gwozdz, R.; Walaszczyk, K. I.

    1992-07-01

    two areas. This suggests to us that we are dealing with identical phenomena, where precipitation may affect both types of environments. Our method of study allows correlation (with a resolution of better than 10 ky) between marine and terrestrial deposits, timing of extinctions, estimates of accumulation rates plus realistic time estimates of magnetochrons. A study of the Uppermost Cretaceous chalk at the locality Nye Klov in North Jylland allows us to fix the extinction pattern of marine benthic fossils in a time frame. Detailed analysis of the boundary bed at Stevns Klint Karlstrup Quarry and Caravaca, Spain point at presence of two sediment pulses indicating a duration of Fish Clay time of around 40 ky. References: Berggren W. A., Kent D. V., and Flynn J. J. (1985) In The chronology of the geological record (ed. N. J. Snelling) Geol. Soc. Amer. Mem. 10, 141-195. Fisher A. G. and Bottjer D. J. (1991) Orbital forcing and sedimentary sequences. J. Sed. Petr. 61, 1063-1069. Hansen H. J., Rasmussen K. L., and Gwordz R. (1989) Cahiers de la Reserve Geologique de Haute Provence 1, 83-90. Hansen H. J., Rasmussen K. L., Gwordz R., Hansen J. M., and Radwanski A. (190) Acta Geologica Polinica 39, 1-12.

  16. Mapping the North Sea base-Quaternary: using 3D seismic to fill a gap in the geological record

    Science.gov (United States)

    Lamb, Rachel; Huuse, Mads; Stewart, Margaret; Brocklehurst, Simon H.

    2014-05-01

    The identification and mapping of the base-Quaternary boundary in the central parts of the North Sea is problematic due to the change from an unconformable transition between Pliocene and Pleistocene deltaic deposits in the southern North Sea to a conformable one further north (Sejrup et al 1991; Gatliff et al 1994). The best estimates of the transition use seismic reflection data to identify a 'crenulated reflector' (Buckley 2012), or rely on correlating sparse biostratigraphy (Cameron et al 1987). Recent integration of biostratigraphy, pollen analysis, paleomagnetism and amino acid analysis in the Dutch and Danish sectors (Rasmussen et al 2005; Kuhlmann et al 2006) allows greater confidence in the correlation to a regional 3D seismic dataset and show that the base-Quaternary can be mapped across the entire basin. The base-Quaternary has been mapped using the PGS MegaSurvey dataset from wells in the Danish Sector along the initially unconformable horizon and down the delta front into the more conformable basin giving a high degree of confidence in the horizon pick. The mapped horizon is presented here alongside the difference between this new interpretation and the previously interpreted base-Quaternary (Buckley 2012). The revised base-Quaternary surface reaches a depth of 1248 ms TWT or approximately 1120 m (assuming average velocity of 1800 m/s) showing an elongate basin shape that follows the underlying structure of the Central Graben. The difference between the revised base-Quaternary and the traditional base-Quaternary reaches a maximum of over 600 ms TWT or approximately 540 m in the south-west with over 300 ms TWT or approximately 270 m at the Josephine well (56° 36.11'N, 2° 27.09'E) in the centre of the basin. Mapping this new base-Quaternary allows for the interpretation of the paleo-envionrment during the earliest Quaternary. Seismic attribute analysis indicates a deep water basin with sediment deposition from multiple deltas and redistribution by deep

  17. New insights into the earliest Quaternary environments in the Central North Sea from 3D seismic

    Science.gov (United States)

    Lamb, Rachel; Huuse, Mads; Stewart, Margaret; Brocklehurst, Simon H.

    2014-05-01

    In the past the transition between an unconformable surface in the south to a conformable horizon towards the north has made identification and mapping the base-Quaternary in the central North Sea difficult (Sejrup et al 1991; Gatliff et al 1994). However recent integration of biostratigraphy, pollen analysis, paleomagnetism and amino acid analysis in the Dutch and Danish sectors (Rasmussen et al 2005; Kuhlmann et al 2006) has allowed greater confidence in the correlation to the region 3D seismic datasets and thus has allowed the base-Quaternary to be mapped across the entire basin. The base-Quaternary has been mapped using the PGS MegaSurvey dataset from wells in the Danish Sector along the initially unconformable horizon and down the delta front into the more conformable basin giving a high degree of confidence in the horizon pick. The revised base-Quaternary surface reaches a depth of 1248 ms TWT with an elongate basin shape which is significantly deeper than the traditionally mapped surface. Using RMS amplitudes and other seismic attributes the revised base-Quaternary has been investigated along the horizon and in time slice to interpret the environments of the earliest Quaternary prior to the onset of glaciation. Combined with analysis of aligned elongate furrows over 10 km long, 100 m wide and 100 m deep suggest a deep marine environment in an almost enclosed basin with persistent strong NW-SE bottom currents in the deepest parts. Pockmarks were formed by the escape of shallow gas on the sides of a small delta in the eastern part of the basin. The progradation of large deltas from both the north and south into the basin make up the majority of the deposition of sediment into the basin. Key Words: base-Quaternary; seismic interpretation; paleoenvironments References: Gatliff, R.W, Richards, P.C, Smith, K, Graham, C.C, McCormac, M, Smith, N.J.P, Long, D, Cameron, T.D.J, Evans, D, Stevenson, A.G, Bulat, J, Ritchie, J.D, (1994) 'United Kingdom offshore regional

  18. Conformal partition functions of critical percolation from D 3 thermodynamic Bethe Ansatz equations

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    Morin-Duchesne, Alexi; Klümper, Andreas; Pearce, Paul A.

    2017-08-01

    Using the planar Temperley-Lieb algebra, critical bond percolation on the square lattice can be reformulated as a loop model. In this form, it is incorporated as {{ L}}{{ M}}(2, 3) in the Yang-Baxter integrable family of logarithmic minimal models {{ L}}{{ M}}( p, p\\prime) . We consider this model of percolation in the presence of boundaries and with periodic boundary conditions. Inspired by Kuniba, Sakai and Suzuki, we rewrite the recently obtained infinite Y-system of functional equations. In this way, we obtain nonlinear integral equations in the form of a closed finite set of TBA equations described by a D 3 Dynkin diagram. Following the methods of Klümper and Pearce, we solve the TBA equations for the conformal finite-size corrections. For the ground states of the standard modules on the strip, these agree with the known central charge c  =  0 and conformal weights Δ1, s for \\renewcommand≥≥slant} s\\in {{ Z}≥slant 1} with Δr, s=\\big((3r-2s){\\hspace{0pt}}^2-1\\big)/24 . For the periodic case, the finite-size corrections agree with the conformal weights Δ0, s , Δ1, s with \\renewcommand{≥{≥slant} s\\in\\frac{1}{2}{{ Z}≥slant 0} . These are obtained analytically using Rogers dilogarithm identities. We incorporate all finite excitations by formulating empirical selection rules for the patterns of zeros of all the eigenvalues of the standard modules. We thus obtain the conformal partition functions on the cylinder and the modular invariant partition function (MIPF) on the torus. By applying q-binomial and q-Narayana identities, it is shown that our refined finitized characters on the strip agree with those of Pearce, Rasmussen and Zuber. For percolation on the torus, the MIPF is a non-diagonal sesquilinear form in affine u(1) characters given by the u(1) partition function Z2, 3(q)=Z2, 3{Circ}(q) . The u(1) operator content is {{ N}}Δ, \\barΔ=1 for Δ=\\barΔ=-\\frac{1}{24}, \\frac{35}{24} and {{ N}}Δ, \\barΔ=2 for

  19. Indicaciones quirúrgicas de la epilepsia en la niñez Surgical indications in pediatric epilepsy

    Directory of Open Access Journals (Sweden)

    María Isabel Bragatti Winckler

    2007-01-01

    Full Text Available Con el objetivo de presentar el seguimiento de los pacientes ambulatorios de la clínica de epilepsia refractaria del Hospital de Clínicas de Porto Alegre (HCPA, Brasil, se hizo una revisión de la literatura de las epilepsias y síndromes epilépticos del niño y del adolescente, las indicaciones quirúrgicas y los métodos de evaluación. Los casos de epilepsia recomendados por la Subcomisión de Cirugía de la Epilepsia Pediátrica de la Liga Internacional Contra las Epilepsias para evaluación quirúrgica son: displasia cortical, esclerosis tuberosa, polimicrogiria, hamartoma hipotalámico, síndromes hemisféricos, síndromes de Sturge-Weber, Síndrome de Rasmussen, Síndrome de Landau-Kleffner y otras situaciones como tumores o alteraciones vasculares. Se recomienda la formación de centros de referencia que cuenten con métodos de evaluación funcional y de neuroimagen, así como equipo multidisciplinario formado por neurólogos, neurocirujanos, neurofisiólogos, neuropediatras, neuropsicólogos, patólogos, neurorradiólogos y técnicos en electroneurofisiología que mantengan los estándares impuestos de forma estricta. La formación de estos centros en países en desarrollo parece viable, con la cooperación de las regiones con mayores recursos. Numerosos estudios han demostrado una mejoría de la calidad de vida con reducción en la frecuencia de crisis diarias. En el HCPA se desarrolla un estudio de seguimiento ambulatorio de casos de epilepsias refractarias todavía en investigación y tratamiento clínico. La cirugía de la epilepsia es potencialmente curativa y es posible utilizarla en la población infantil.With the goal of presenting follow-up data from patients seen at the Refractory Epilepsy out-patient clinic of the Hospital de Clínicas de Porto Alegre (HCPA, Brazil, we reviewed the literature on childhood and adolescent epilepsy and epileptic syndromes with indication for surgical treatment. The International League

  20. Estimating concentrations of fine-grained and total suspended sediment from close-range remote sensing imagery

    Science.gov (United States)

    Mosbrucker, Adam; Spicer, Kurt R.; Christianson, Tami; Uhrich, Mark A.

    2015-01-01

    Fluvial sediment, a vital surface water resource, is hazardous in excess. Suspended sediment, the most prevalent source of impairment of river systems, can adversely affect flood control, navigation, fisheries and aquatic ecosystems, recreation, and water supply (e.g., Rasmussen et al., 2009; Qu, 2014). Monitoring programs typically focus on suspended-sediment concentration (SSC) and discharge (SSQ). These time-series data are used to study changes to basin hydrology, geomorphology, and ecology caused by disturbances. The U.S. Geological Survey (USGS) has traditionally used physical sediment sample-based methods (Edwards and Glysson, 1999; Nolan et al., 2005; Gray et al., 2008) to compute SSC and SSQ from continuous streamflow data using a sediment transport-curve (e.g., Walling, 1977) or hydrologic interpretation (Porterfield, 1972). Accuracy of these data is typically constrained by the resources required to collect and analyze intermittent physical samples. Quantifying SSC using continuous instream turbidity is rapidly becoming common practice among sediment monitoring programs. Estimations of SSC and SSQ are modeled from linear regression analysis of concurrent turbidity and physical samples. Sediment-surrogate technologies such as turbidity promise near real-time information, increased accuracy, and reduced cost compared to traditional physical sample-based methods (Walling, 1977; Uhrich and Bragg, 2003; Gray and Gartner, 2009; Rasmussen et al., 2009; Landers et al., 2012; Landers and Sturm, 2013; Uhrich et al., 2014). Statistical comparisons among SSQ computation methods show that turbidity-SSC regression models can have much less uncertainty than streamflow-based sediment transport-curves or hydrologic interpretation (Walling, 1977; Lewis, 1996; Glysson et al., 2001; Lee et al., 2008). However, computation of SSC and SSQ records from continuous instream turbidity data is not without challenges; some of these include environmental fouling, calibration, and

  1. Efficacy of anti-inflammatory therapy in a model of acute seizures and in a population of pediatric drug resistant epileptics.

    Directory of Open Access Journals (Sweden)

    Nicola Marchi

    2011-03-01

    Full Text Available Targeting pro-inflammatory events to reduce seizures is gaining momentum. Experimentally, antagonism of inflammatory processes and of blood-brain barrier (BBB damage has been demonstrated to be beneficial in reducing status epilepticus (SE. Clinically, a role of inflammation in the pathophysiology of drug resistant epilepsies is suspected. However, the use anti-inflammatory drug such as glucocorticosteroids (GCs is limited to selected pediatric epileptic syndromes and spasms. Lack of animal data may be one of the reasons for the limited use of GCs in epilepsy. We evaluated the effect of the CG dexamethasone in reducing the onset and the severity of pilocarpine SE in rats. We assessed BBB integrity by measuring serum S100β and Evans Blue brain extravasation. Electrophysiological monitoring and hematologic measurements (WBCs and IL-1β were performed. We reviewed the effect of add on dexamethasone treatment on a population of pediatric patients affected by drug resistant epilepsy. We excluded subjects affected by West, Landau-Kleffner or Lennox-Gastaut syndromes and Rasmussen encephalitis, known to respond to GCs or adrenocorticotropic hormone (ACTH. The effect of two additional GCs, methylprednisolone and hydrocortisone, was also reviewed in this population. When dexamethasone treatment preceded exposure to the convulsive agent pilocarpine, the number of rats developing status epilepticus (SE was reduced. When SE developed, the time-to-onset was significantly delayed compared to pilocarpine alone and mortality associated with pilocarpine-SE was abolished. Dexamethasone significantly protected the BBB from damage. The clinical study included pediatric drug resistant epileptic subjects receiving add on GC treatments. Decreased seizure frequency (≥ 50% or interruption of status epilepticus was observed in the majority of the subjects, regardless of the underlying pathology. Our experimental results point to a seizure-reducing effect of

  2. Análisis estructural a partir de la teoría de las redes sociales: un nuevo enfoque de un problema clásico.

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    Ramos Carbajal, Carmen.

    2003-01-01

    Full Text Available El análisis input-output es una herramienta de incuestionable utilidad en la elaboración de estudios económicos, ya que permite recoger no sólo las relaciones entre los distintos sectores, sino también otros agregados de interés como, por ejemplo, la demanda final, las importaciones y exportaciones o el valor añadido bruto. El esquema contable subyacente en una tabla input-output refleja las interdependencias económicas latentes en la estructura productiva, a través del conjunto de relaciones intersectoriales consideradas. El análisis estructural supone una importante ayuda no sólo en la toma de decisiones de política económica, sino también constituye un requisito indispensable y previo a las tareas de predicción necesarias en un contexto empresarial. Tradicionalmente, para efectuar dicho análisis en una economía se han venido aplicando los conocidos coeficientes de Chenery y Watanabe y Rasmussen, los cuales han sido sometidos a numerosas críticas. Frente a esta óptica clásica de análisis, planteamos en este trabajo una alternativa de estudio del marco input-output, basada en la teoría de redes sociales. Su aplicación presenta un gran potencial al permitir simplificar y describir con detalle el esquema de relaciones intersectoriales, ventajas que apenas han sido explotadas, a nuestro juicio, en el marco input-output.

  3. Characterizing Uncertainties in Hydrologic Extremes: Statistical vs. Dynamical Downscaling

    Science.gov (United States)

    Mauger, G. S.; Salathe, E. P., Jr.

    2013-12-01

    Numerous agencies are now charged with considering the impacts of climate change in management decisions, both from the standpoint of adapting to changing conditions and minimizing emissions of greenhouse gases. These decisions require robust projections of change and defensible estimates of their uncertainty. We present work that is specifically focused on characterizing the uncertainty in projections of hydrologic extremes. Much recent work has been devoted to characterizing the uncertainty in hydrologic projections due to differences in downscaling methodology (e.g., Abatzoglou and Brown, 2012; Bürger et al., 2012; Rasmussen et al., 2011; Wetterhall et al., 2012) and among hydrologic models (e.g., Bennett et al., 2012; Clark et al., 2008; Fenicia et al., 2008; Smith and Marshall, 2010; Vano et al., 2012). These have established a basis for such analyses, but have generally focused on the implications for monthly and annual flows rather than flow extremes. In addition, few among these have been focused within the Pacific Northwest. In this work we assess the uncertainty in projected changes to hydrologic extremes associated with dynamical vs. statistical downscaling. The analysis is focused on 3 distinct watersheds within the Pacific Northwest - the Skagit, Green, and Willamette river basins. Results highlight the sensitivity of flood projections to downscaling approach and hydrologic model assumptions. Sensitivities are characterized as a function of geographic location, hydrologic regime, and climate - identifying circumstances under which projections are reliable and others in which answers differ markedly based on methodology. For example, one notable result is that dynamically downscaled projections appear to refute the assumed relationship between watershed type (snow-dominant vs. rain-dominant) and projected changes to flood risk - currently considered a key indicator of future flood risk. Results presented here provide key information for decision

  4. JACOS: AI-based simulation system for man-machine system behavior in NPP

    Energy Technology Data Exchange (ETDEWEB)

    Yoshida, Kazuo; Yokobayashi, Masao; Tanabe, Fumiya [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment; Kawase, Katsumi [CSK Corp., Tokyo (Japan); Komiya, Akitoshi [Computer Associated Laboratory, Inc., Hitachinaka, Ibaraki (Japan)

    2001-08-01

    A prototype of a computer simulation system named JACOS (JAERI COgnitive Simulation system) has been developed at JAERI (Japan Atomic Energy Research Institute) to simulate the man-machine system behavior in which both the cognitive behavior of a human operator and the plant behavior affect each other. The objectives of this system development is to provide man-machine system analysts with detailed information on the cognitive process of an operator and the plant behavior affected by operator's actions in accidental situations of a nuclear power plant. The simulation system consists of an operator model and a plant model which are coupled dynamically. The operator model simulates an operator's cognitive behavior in accidental situations based on the decision ladder model of Rasmussen, and is implemented using the AI-techniques of the distributed cooperative inference method with the so-called blackboard architecture. Rule-based behavior is simulated using knowledge representation with If-Then type of rules. Knowledge-based behavior is simulated using knowledge representation with MFM (Multilevel Flow Modeling) and qualitative reasoning method. Cognitive characteristics of attentional narrowing, limitation of short-term memory, and knowledge recalling from long-term memory are also taken into account. The plant model of a 3-loop PWR is also developed using a best estimate thermal-hydraulic analysis code RELAP5/MOD2. This report is prepared as User's Manual for JACOS. The first chapter of this report describes both operator and plant models in detail. The second chapter includes instructive descriptions for program installation, building of a knowledge base for operator model, execution of simulation and analysis of simulation results. The examples of simulation with JACOS are shown in the third chapter. (author)

  5. Frontal Lobe Decortication (Frontal Lobectomy with Ventricular Preservation) in Epilepsy-Part 1: Anatomic Landmarks and Surgical Technique.

    Science.gov (United States)

    Wen, Hung Tzu; Da Róz, Leila Maria; Rhoton, Albert L; Castro, Luiz Henrique Martins; Teixeira, Manoel Jacobsen

    2017-02-01

    An extensive frontal resection is a frequently performed neurosurgical procedure, especially for treating brain tumor and refractory epilepsy. However, there is a paucity of reports available regarding its surgical anatomy and technique. We sought to present the anatomic landmarks and surgical technique of the frontal lobe decortication (FLD) in epilepsy. The goals were to maximize the gray matter removal, spare primary and supplementary motor areas, and preserve the frontal horn. The anatomic study was based on dissections performed in 15 formalin-fixed adult cadaveric heads. The clinical experience with 15 patients is summarized. FLD consists of 5 steps: 1) coagulation and section of arterial branches of lateral surface; 2) paramedian subpial resection 3 cm ahead of the precentral sulcus to reach the genu of corpus callosum; 3) resection of gray matter of lateral surface, preserving the frontal horn; 4) removal of gray matter of basal surface preserving olfactory tract; 5) removal of gray matter of the medial surface under the rostrum of corpus callosum. The frontal horn was preserved in all 15 patients; 12 patients (80%) had no complications; 2 patients presented temporary hemiparesis; and 1 Rasmussen syndrome patient developed postoperative fever. The best seizure control was in cases with focal magnetic resonance imaging abnormalities limited to the frontal lobe. FLD is an anatomy-based surgical technique for extensive frontal lobe resection. It presents reliable anatomic landmarks, selective gray matter removal, preservation of frontal horn, and low complication rate in our series. It can be an alternative option to the classical frontal lobectomy. Copyright © 2016 Elsevier Inc. All rights reserved.

  6. Using the decision ladder to understand road user decision making at actively controlled rail level crossings.

    Science.gov (United States)

    Mulvihill, Christine M; Salmon, Paul M; Beanland, Vanessa; Lenné, Michael G; Read, Gemma J M; Walker, Guy H; Stanton, Neville A

    2016-09-01

    Rail level crossings (RLXs) represent a key strategic risk for railways worldwide. Despite enforcement and engineering countermeasures, user behaviour at RLXs can often confound expectations and erode safety. Research in this area is limited by a relative absence of insights into actual decision making processes and a focus on only a subset of road user types. One-hundred and sixty-six road users (drivers, motorcyclists, cyclists and pedestrians) completed a diary entry for each of 457 naturalistic encounters with RLXs when a train was approaching. The final eligible sample comprised 94 participants and 248 encounters at actively controlled crossings where a violation of the active warnings was possible. The diary incorporated Critical Decision Method probe questions, which enabled user responses to be mapped onto Rasmussen's decision ladder. Twelve percent of crossing events were non-compliant. The underlying decision making was compared to compliant events and a reference decision model to reveal important differences in the structure and type of decision making within and between road user groups. The findings show that engineering countermeasures intended to improve decision making (e.g. flashing lights), may have the opposite effect for some users because the system permits a high level of flexibility for circumvention. Non-motorised users were more likely to access information outside of the warning signals because of their ability to achieve greater proximity to the train tracks and the train itself. The major conundrum in resolving these issues is whether to restrict the amount of time and information available to users so that it cannot be used for circumventing the system or provide more information to help users make safe decisions. Copyright © 2016 Elsevier Ltd. All rights reserved.

  7. Chronic subthreshold cortical stimulation for adult drug-resistant focal epilepsy: safety, feasibility, and technique.

    Science.gov (United States)

    Kerezoudis, Panagiotis; Grewal, Sanjeet S; Stead, Matthew; Lundstrom, Brian Nils; Britton, Jeffrey W; Shin, Cheolsu; Cascino, Gregory D; Brinkmann, Benjamin H; Worrell, Gregory A; Van Gompel, Jamie J

    2017-10-20

    OBJECTIVE Epilepsy surgery is effective for lesional epilepsy, but it can be associated with significant morbidity when seizures originate from eloquent cortex that is resected. Here, the objective was to describe chronic subthreshold cortical stimulation and evaluate its early surgical safety profile in adult patients with epilepsy originating from seizure foci in cortex that is not amenable to resection. METHODS Adult patients with focal drug-resistant epilepsy underwent intracranial electroencephalography monitoring for evaluation of resection. Those with seizure foci in eloquent cortex were not candidates for resection and were offered a short therapeutic trial of continuous subthreshold cortical stimulation via intracranial monitoring electrodes. After a successful trial, electrodes were explanted and permanent stimulation hardware was implanted. RESULTS Ten patients (6 males) who underwent chronic subthreshold cortical stimulation between 2014 and 2016 were included. Based on radiographic imaging, intracranial pathologies included cortical dysplasia (n = 3), encephalomalacia (n = 3), cortical tubers (n = 1), Rasmussen encephalitis (n = 1), and linear migrational anomaly (n = 1). The duration of intracranial monitoring ranged from 3 to 20 days. All patients experienced an uneventful postoperative course and were discharged home with a median length of stay of 10 days. No postoperative surgical complications developed (median follow-up length 7.7 months). Seizure severity and seizure frequency improved in all patients. CONCLUSIONS The authors' institutional experience with this small group shows that chronic subthreshold cortical stimulation can be safely and effectively performed in appropriately selected patients without postoperative complications. Future investigation will provide further insight to recently published results regarding mechanism and efficacy of this novel and promising intervention.

  8. Autoimmune Epilepsy: Some Epilepsy Patients Harbor Autoantibodies to Glutamate Receptors and dsDNA on both Sides of the Blood-brain Barrier, which may Kill Neurons and Decrease in Brain Fluids after Hemispherotomy

    Directory of Open Access Journals (Sweden)

    Yonatan Ganor

    2004-01-01

    Full Text Available Purpose: Elucidating the potential contribution of specific autoantibodies (Ab's to the etiology and/or pathology of some human epilepsies. Methods: Six epilepsy patients with Rasmussen's encephalitis (RE and 71 patients with other epilepsies were tested for Ab's to the –B— peptide (amino acids 372-395 of the glutamate/AMPA subtype 3 receptor (GluR3B peptide, double-stranded DNA (dsDNA, and additional autoimmune disease-associated autoantigens, and for the ability of their serum and cerebrospinal-fluid (CSF to kill neurons. Results: Elevated anti-GluR3B Ab's were found in serum and CSF of most RE patients, and in serum of 17/71 (24% patients with other epilepsies. In two RE patients, anti-GluR3B Ab's decreased drastically in CSF following functional-hemispherotomy, in association with seizure cessation and neurological improvement. Serum and CSF of two RE patients, and serum of 12/71 (17% patients with other epilepsies, contained elevated anti-dsDNA Ab's, the hallmark of systemic-lupus-erythematosus. The sera (but not the CSF of some RE patients contained also clinically elevated levels of –classical— autoimmune Ab's to glutamic-acid-decarboxylase, cardiolipin, β2-glycoprotein-I and nuclear-antigens SS-A and RNP-70. Sera and CSF of some RE patients caused substantial death of hippocampal neurons. Conclusions: Some epilepsy patients harbor Ab's to GluR3 and dsDNA on both sides of the blood-brain barrier, and additional autoimmune Ab's only in serum. Since all these Ab's may be detrimental to the nervous system and/or peripheral organs, we recommend testing for their presence in epilepsy, and silencing their activity in Ab-positive patients.

  9. Fifty Years of THERP and Human Reliability Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Ronald L. Boring

    2012-06-01

    In 1962 at a Human Factors Society symposium, Alan Swain presented a paper introducing a Technique for Human Error Rate Prediction (THERP). This was followed in 1963 by a Sandia Laboratories monograph outlining basic human error quantification using THERP and, in 1964, by a special journal edition of Human Factors on quantification of human performance. Throughout the 1960s, Swain and his colleagues focused on collecting human performance data for the Sandia Human Error Rate Bank (SHERB), primarily in connection with supporting the reliability of nuclear weapons assembly in the US. In 1969, Swain met with Jens Rasmussen of Risø National Laboratory and discussed the applicability of THERP to nuclear power applications. By 1975, in WASH-1400, Swain had articulated the use of THERP for nuclear power applications, and the approach was finalized in the watershed publication of the NUREG/CR-1278 in 1983. THERP is now 50 years old, and remains the most well known and most widely used HRA method. In this paper, the author discusses the history of THERP, based on published reports and personal communication and interviews with Swain. The author also outlines the significance of THERP. The foundations of human reliability analysis are found in THERP: human failure events, task analysis, performance shaping factors, human error probabilities, dependence, event trees, recovery, and pre- and post-initiating events were all introduced in THERP. While THERP is not without its detractors, and it is showing signs of its age in the face of newer technological applications, the longevity of THERP is a testament of its tremendous significance. THERP started the field of human reliability analysis. This paper concludes with a discussion of THERP in the context of newer methods, which can be seen as extensions of or departures from Swain’s pioneering work.

  10. Cellular injury and neuroinflammation in children with chronic intractable epilepsy

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    Rosenow Joshua

    2009-12-01

    Full Text Available Abstract Objective To elucidate the presence and potential involvement of brain inflammation and cell death in neurological morbidity and intractable seizures in childhood epilepsy, we quantified cell death, astrocyte proliferation, microglial activation and cytokine release in brain tissue from patients who underwent epilepsy surgery. Methods Cortical tissue was collected from thirteen patients with intractable epilepsy due to focal cortical dysplasia (6, encephalomalacia (5, Rasmussen's encephalitis (1 or mesial temporal lobe epilepsy (1. Sections were processed for immunohistochemistry using markers for neuron, astrocyte, microglia or cellular injury. Cytokine assay was performed on frozen cortices. Controls were autopsy brains from eight patients without history of neurological diseases. Results Marked activation of microglia and astrocytes and diffuse cell death were observed in epileptogenic tissue. Numerous fibrillary astrocytes and their processes covered the entire cortex and converged on to blood vessels, neurons and microglia. An overwhelming number of neurons and astrocytes showed DNA fragmentation and its magnitude significantly correlated with seizure frequency. Majority of our patients with abundant cell death in the cortex have mental retardation. IL-1beta, IL-8, IL-12p70 and MIP-1beta were significantly increased in the epileptogenic cortex; IL-6 and MCP-1 were significantly higher in patients with family history of epilepsy. Conclusions Our results suggest that active neuroinflammation and marked cellular injury occur in pediatric epilepsy and may play a common pathogenic role or consequences in childhood epilepsy of diverse etiologies. Our findings support the concept that immunomodulation targeting activated microglia and astrocytes may be a novel therapeutic strategy to reduce neurological morbidity and prevent intractable epilepsy.

  11. Cellular injury and neuroinflammation in children with chronic intractable epilepsy.

    Science.gov (United States)

    Choi, Jieun; Nordli, Douglas R; Alden, Tord D; DiPatri, Arthur; Laux, Linda; Kelley, Kent; Rosenow, Joshua; Schuele, Stephan U; Rajaram, Veena; Koh, Sookyong

    2009-12-19

    To elucidate the presence and potential involvement of brain inflammation and cell death in neurological morbidity and intractable seizures in childhood epilepsy, we quantified cell death, astrocyte proliferation, microglial activation and cytokine release in brain tissue from patients who underwent epilepsy surgery. Cortical tissue was collected from thirteen patients with intractable epilepsy due to focal cortical dysplasia (6), encephalomalacia (5), Rasmussen's encephalitis (1) or mesial temporal lobe epilepsy (1). Sections were processed for immunohistochemistry using markers for neuron, astrocyte, microglia or cellular injury. Cytokine assay was performed on frozen cortices. Controls were autopsy brains from eight patients without history of neurological diseases. Marked activation of microglia and astrocytes and diffuse cell death were observed in epileptogenic tissue. Numerous fibrillary astrocytes and their processes covered the entire cortex and converged on to blood vessels, neurons and microglia. An overwhelming number of neurons and astrocytes showed DNA fragmentation and its magnitude significantly correlated with seizure frequency. Majority of our patients with abundant cell death in the cortex have mental retardation. IL-1beta, IL-8, IL-12p70 and MIP-1beta were significantly increased in the epileptogenic cortex; IL-6 and MCP-1 were significantly higher in patients with family history of epilepsy. Our results suggest that active neuroinflammation and marked cellular injury occur in pediatric epilepsy and may play a common pathogenic role or consequences in childhood epilepsy of diverse etiologies. Our findings support the concept that immunomodulation targeting activated microglia and astrocytes may be a novel therapeutic strategy to reduce neurological morbidity and prevent intractable epilepsy.

  12. Identification of the human factors contributing to maintenance failures in a petroleum operation.

    Science.gov (United States)

    Antonovsky, Ari; Pollock, Clare; Straker, Leon

    2014-03-01

    This research aimed to identify the most frequently occurring human factors contributing to maintenance-related failures within a petroleum industry organization. Commonality between failures will assist in understanding reliability in maintenance processes, thereby preventing accidents in high-hazard domains. Methods exist for understanding the human factors contributing to accidents. Their application in a maintenance context mainly has been advanced in aviation and nuclear power. Maintenance in the petroleum industry provides a different context for investigating the role that human factors play in influencing outcomes. It is therefore worth investigating the contributing human factors to improve our understanding of both human factors in reliability and the factors specific to this domain. Detailed analyses were conducted of maintenance-related failures (N = 38) in a petroleum company using structured interviews with maintenance technicians. The interview structure was based on the Human Factor Investigation Tool (HFIT), which in turn was based on Rasmussen's model of human malfunction. A mean of 9.5 factors per incident was identified across the cases investigated.The three most frequent human factors contributing to the maintenance failures were found to be assumption (79% of cases), design and maintenance (71%), and communication (66%). HFIT proved to be a useful instrument for identifying the pattern of human factors that recurred most frequently in maintenance-related failures. The high frequency of failures attributed to assumptions and communication demonstrated the importance of problem-solving abilities and organizational communication in a domain where maintenance personnel have a high degree of autonomy and a wide geographical distribution.

  13. Assessment for Operator Confidence in Automated Space Situational Awareness and Satellite Control Systems

    Science.gov (United States)

    Gorman, J.; Voshell, M.; Sliva, A.

    2016-09-01

    The United States is highly dependent on space resources to support military, government, commercial, and research activities. Satellites operate at great distances, observation capacity is limited, and operator actions and observations can be significantly delayed. Safe operations require support systems that provide situational understanding, enhance decision making, and facilitate collaboration between human operators and system automation both in-the-loop, and on-the-loop. Joint cognitive systems engineering (JCSE) provides a rich set of methods for analyzing and informing the design of complex systems that include both human decision-makers and autonomous elements as coordinating teammates. While, JCSE-based systems can enhance a system analysts' understanding of both existing and new system processes, JCSE activities typically occur outside of traditional systems engineering (SE) methods, providing sparse guidance about how systems should be implemented. In contrast, the Joint Director's Laboratory (JDL) information fusion model and extensions, such as the Dual Node Network (DNN) technical architecture, provide the means to divide and conquer such engineering and implementation complexity, but are loosely coupled to specialized organizational contexts and needs. We previously describe how Dual Node Decision Wheels (DNDW) extend the DNN to integrate JCSE analysis and design with the practicalities of system engineering and implementation using the DNN. Insights from Rasmussen's JCSE Decision Ladders align system implementation with organizational structures and processes. In the current work, we present a novel approach to assessing system performance based on patterns occurring in operational decisions that are documented by JCSE processes as traces in a decision ladder. In this way, system assessment is closely tied not just to system design, but the design of the joint cognitive system that includes human operators, decision-makers, information systems, and

  14. Minimally invasive fixation in tibial plateau fractures using an pre-operative and intra-operative real size 3D printing.

    Science.gov (United States)

    Giannetti, Silvio; Bizzotto, Nicola; Stancati, Andrea; Santucci, Attilio

    2017-03-01

    The purpose of our study was to compare the outcome after minimally invasive reconstruction and internal fixation with and without the use of pre- and intra-operative real size 3D printing for patients with displaced tibial plateau fractures (TPFs). We prospectively followed up 40 consecutive adult patients with closed TPF who underwent surgical treatment of reconstruction of the tibial plateau with the use of minimally invasive fixation. Sixteen patients (group 1) were operated using a pre-operative and intra-operative real size 3D-model, while 24 patients (group 2) were operated without 3D-model printing, but using only pre-operative and intra-operative 3D Tc-scan images. The mean operating time was 148.2±15.9min for group 1 and 174.5±22.2min for group 2 (p=0.041). In addition, the mean intraoperative blood loss was less in group 1 (520mL) than in group 2 (546mL) (p=0.534). After discharge, all patients were followed up at 6 weeks, 12 weeks, 6 months, 1year and then every year post surgically and radiographic evaluation was carried out each time using clinical and radiological Rasmussen's score, with no significant differences between the two groups. Two patients (group 2) developed infection which resolved within 3 weeks after usage of antibiotics. Neither superficial nor deep infections were present in group 1. In all patients, no non-union occurred. No intraoperative, perioperative, or postoperative complications, such as loss of valgus correction, bone fractures, or metallic plate failures were detected at follow-up. In patients operated with the use of 3D-model printing, we found a significant reduction in surgical time. Moreover, the technique without a 3D-model increased the patient's and the surgeon's exposure to radiation. Copyright © 2016 Elsevier Ltd. All rights reserved.

  15. Applying the AcciMap methodology to investigate the tragic Sewol Ferry accident in South Korea.

    Science.gov (United States)

    Lee, Samuel; Moh, Young Bo; Tabibzadeh, Maryam; Meshkati, Najmedin

    2017-03-01

    This study applies the AcciMap methodology, which was originally proposed by Professor Jens Rasmussen (1997), to the analysis of the tragic Sewol Ferry accident in South Korea on April 16, 2014, which killed 304 mostly young people and is considered as a national disaster in that country. This graphical representation, by incorporating associated socio-technical factors into an integrated framework, provides a big-picture to illustrate the context in which an accident occurred as well as the interactions between different levels of the studied system that resulted in that event. In general, analysis of past accidents within the stated framework can define the patterns of hazards within an industrial sector. Such analysis can lead to the definition of preconditions for safe operations, which is a main focus of proactive risk management systems. In the case of the Sewol Ferry accident, a lot of the blame has been placed on the Sewol's captain and its crewmembers. However, according to this study, which relied on analyzing all available sources published in English and Korean, the disaster is the result of a series of lapses and disregards for safety across different levels of government and regulatory bodies, Chonghaejin Company, and the Sewol's crewmembers. The primary layers of the AcciMap framework, which include the political environment and non-proactive governmental body; inadequate regulations and their lax oversight and enforcement; poor safety culture; inconsideration of human factors issues; and lack of and/or outdated standard operating and emergency procedures were not only limited to the maritime industry in South Korea, and the Sewol Ferry accident, but they could also subject any safety-sensitive industry anywhere in the world. Copyright © 2016 Elsevier Ltd. All rights reserved.

  16. Ketogenic diet treatment for pediatric super-refractory status epilepticus.

    Science.gov (United States)

    Appavu, Brian; Vanatta, Lisa; Condie, John; Kerrigan, John F; Jarrar, Randa

    2016-10-01

    We aimed to study whether ketogenic diet (KD) therapy leads to resolution of super-refractory status epilepticus in pediatric patients without significant harm. A retrospective review was performed at Phoenix Children's Hospital on patients with super-refractory status epilepticus undergoing ketogenic diet therapy from 2011 to 2015. Ten children with super-refractory status epilepticus, ages 2-16 years, were identified. 4/10 patients had immune mediated encephalitis, including Rasmussen encephalitis, anti-N-methyl-d-aspartate receptor encephalitis, and post-infectious mycoplasma encephalitis. Other etiologies included Lennox Gastaut Syndrome, non-ketotic hyperglycinemia, PCDH19 and GABRG2 genetic epilepsy, New Onset Refractory Status Epilepticus, and Febrile Infection-Related Epilepsy Syndrome. 4/10 patients' EEG features suggested focal with status epilepticus, and 6/10 suggested generalized with status epilepticus. Median hospital length was 61days and median ICU length was 27days. The median number of antiepileptic medications prior to diet initiation was 3.0 drugs, and the median after ketogenic diet treatment was 3.5 drugs. Median duration of status epilepticus prior to KD was 18days. 9/10 patients had resolution of super-refractory status epilepticus in a median of 7days after diet initiation. 8/9 patients were weaned off anesthesia within 15days of diet initiation, and within 1day of achieving ketonuria. 1/10 patients experienced side effects on the diet requiring supplementation. Most patients achieved resolution of status epilepticus on KD therapy, suggesting it could be an effective therapy that can be utilized early in the treatment of children with super refractory status epilepticus. Copyright © 2016. Published by Elsevier Ltd.

  17. Impact of Climate Change on Heavy Precipitation Events : Application of Extreme Value Theory to a Future Climate Simulation over the Colorado Headwaters Region

    Science.gov (United States)

    Ikeda, K.; Prein, A.; Rasmussen, R.; Liu, C.; Holland, G. J.

    2012-12-01

    Heavy precipitation cause devastating warm-season floods and cool-season snow and icing hazards that impact socio-economic communities of various scales. The frequency and severity of extreme precipitation events potentially are likely to be impacted by climate change. In this study we will investigate potential change in extreme precipitation intensity in a future climate over the Colorado headwaters region based on an extreme value approach ("peak-over-threshold" approach). The data come from Weather Research and Forecasting (WRF) model simulations of current and future climate conducted by the Colorado Headwaters Project (e.g., Rasmussen et al. 2011). The simulations were performed over eight years with 4, 12, and 36 km horizontal grid spacing. In the current study, we first evaluate the model ability to properly represent extreme precipitation events from the current climate simulation. Then we present changes in extreme precipitation intensity in the future climate for different seasons and over eight mountain ranges of the Colorado headwaters region. Our analyses so far have shown that the 4-km model outperformed coarser grid resolution models in representing extreme precipitation compared to Snowpack Telemetry (SNOTEL) surface observations. Overall, the 10-year return level in the future climate increased (more intense extreme precipitation) for all mountain ranges in the cool season. There was a general decrease in the 10-year return level (less intense extreme precipitation) in the warm season. The sign and magnitude of the change shows regional differences possibly related to seasonal storm tracks and characteristics. Detailed analysis from case studies will be presented to illustrate the impacts of a warmer and moister atmosphere on the microphysical structure of storm clouds and surface precipitation distribution.

  18. Evaluating turbidity and suspended-sediment concentration relations from the North Fork Toutle River basin near Mount St. Helens, Washington; annual, seasonal, event, and particle size variations - a preliminary analysis.

    Science.gov (United States)

    Uhrich, Mark A.; Spicer, Kurt R.; Mosbrucker, Adam; Christianson, Tami

    2015-01-01

    Regression of in-stream turbidity with concurrent sample-based suspended-sediment concentration (SSC) has become an accepted method for producing unit-value time series of inferred SSC (Rasmussen et al., 2009). Turbidity-SSC regression models are increasingly used to generate suspended-sediment records for Pacific Northwest rivers (e.g., Curran et al., 2014; Schenk and Bragg, 2014; Uhrich and Bragg, 2003). Recent work developing turbidity-SSC models for the North Fork Toutle River in Southwest Washington (Uhrich et al., 2014), as well as other studies (Landers and Sturm, 2013, Merten et al., 2014), suggests that models derived from annual or greater datasets may not adequately reflect shorter term changes in turbidity-SSC relations, warranting closer inspection of such relations. In-stream turbidity measurements and suspended-sediment samples have been collected from the North Fork Toutle River since 2010. The study site, U.S. Geological Survey (USGS) streamgage 14240525 near Kid Valley, Washington, is 13 river km downstream of the debris avalanche emplaced by the 1980 eruption of Mount St. Helens (Lipman and Mullineaux, 1981), and 2 river km downstream of the large sediment retention structure (SRS) built from 1987–1989 to mitigate the associated sediment hazard. The debris avalanche extends roughly 25 km down valley from the edifice of the volcano and is the primary source of suspended sediment moving past the streamgage (NF Toutle-SRS). Other significant sources are debris flow events and sand deposits upstream of the SRS, which are periodically remobilized and transported downstream. Also, finer material often is derived from the clay-rich original debris avalanche deposit, while coarser material can derive from areas such as fluvially reworked terraces.

  19. People-Technology-Ecosystem Integration: A Framework to Ensure Regional Interoperability for Safety, Sustainability, and Resilience of Interdependent Energy, Water, and Seafood Sources in the (Persian) Gulf.

    Science.gov (United States)

    Meshkati, Najmedin; Tabibzadeh, Maryam; Farshid, Ali; Rahimi, Mansour; Alhanaee, Ghena

    2016-02-01

    The aim of this study is to identify the interdependencies of human and organizational subsystems of multiple complex, safety-sensitive technological systems and their interoperability in the context of sustainability and resilience of an ecosystem. Recent technological disasters with severe environmental impact are attributed to human factors and safety culture causes. One of the most populous and environmentally sensitive regions in the world, the (Persian) Gulf, is on the confluence of an exponentially growing number of two industries--nuclear power and seawater desalination plants--that is changing its land- and seascape. Building upon Rasmussen's model, a macrosystem integrative framework, based on the broader context of human factors, is developed, which can be considered in this context as a "meta-ergonomics" paradigm, for the analysis of interactions, design of interoperability, and integration of decisions of major actors whose actions can affect safety and sustainability of the focused industries during routine and nonroutine (emergency) operations. Based on the emerging realities in the Gulf region, it is concluded that without such systematic approach toward addressing the interdependencies of water and energy sources, sustainability will be only a short-lived dream and prosperity will be a disappearing mirage for millions of people in the region. This multilayered framework for the integration of people, technology, and ecosystem--which has been applied to the (Persian) Gulf--offers a viable and vital approach to the design and operation of large-scale complex systems wherever the nexus of water, energy, and food sources are concerned, such as the Black Sea. © 2016, Human Factors and Ergonomics Society.

  20. Activation of satellite cells and the regeneration of human skeletal muscle are expedited by ingestion of nonsteroidal anti-inflammatory medication.

    Science.gov (United States)

    Mackey, Abigail L; Rasmussen, Lotte K; Kadi, Fawzi; Schjerling, Peter; Helmark, Ida C; Ponsot, Elodie; Aagaard, Per; Durigan, João Luiz Q; Kjaer, Michael

    2016-06-01

    With this study we investigated the role of nonsteroidal anti-inflammatory drugs (NSAIDs) in human skeletal muscle regeneration. Young men ingested NSAID [1200 mg/d ibuprofen (IBU)] or placebo (PLA) daily for 2 wk before and 4 wk after an electrical stimulation-induced injury to the leg extensor muscles of one leg. Muscle biopsies were collected from the vastus lateralis muscles before and after stimulation (2.5 h and 2, 7, and 30 d) and were assessed for satellite cells and regeneration by immunohistochemistry and real-time RT-PCR, and we also measured telomere length. After injury, and compared with PLA, IBU was found to augment the proportion of ActiveNotch1(+) satellite cells at 2 d [IBU, 29 ± 3% vs. PLA, 19 ± 2% (means ± sem)], satellite cell content at 7 d [IBU, 0.16 ± 0.01 vs. PLA, 0.12 ± 0.01 (Pax7(+) cells/fiber)], and to expedite muscle repair at 30 d. The PLA group displayed a greater proportion of embryonic myosin(+) fibers and a residual ∼2-fold increase in mRNA levels of matrix proteins (all P cells and muscle remodeling during large-scale regeneration of injured human skeletal muscle.-Mackey, A. L., Rasmussen, L. K., Kadi, F., Schjerling, P., Helmark, I. C., Ponsot, E., Aagaard, P., Durigan, J. L. Q., Kjaer, M. Activation of satellite cells and the regeneration of human skeletal muscle are expedited by ingestion of nonsteroidal anti-inflammatory medication. © FASEB.

  1. Gas hydrate nucleation

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-12-31

    The overall aim of the project was to gain more knowledge about the kinetics of gas hydrate formation especially the early growth phase. Knowledge of kinetics of gas hydrate formation is important and measurements of gas hydrate particle size and concentration can contribute to improve this knowledge. An experimental setup for carrying out experimental studies of the nucleation and growth of gas hydrates has been constructed and tested. Multi wavelength extinction (MWE) was the experimental technique selected for obtaining particle diameter and concentration. The principle behind MWE is described as well as turbidity spectrum analysis that in an initial stage of the project was considered as an alternative experimental technique. Details of the experimental setup and its operation are outlined. The measuring cell consists of a 1 litre horizontal tube sustaining pressures up to 200 bar. Laser light for particle size determination can be applied through sapphire windows. A description of the various auxiliary equipment and of another gas hydrate cell used in the study are given. A computer program for simulation and analysis of gas hydrate experiments is based on the gas hydrate kinetics model proposed by Skovborg and Rasmussen (1993). Initial measurements showed that knowledge of the refractive index of gas hydrates was important in order to use MWE. An experimental determination of the refractive index of methane and natural gas hydrate is described. The test experiments performed with MWE on collectives of gas hydrate particles and experiments with ethane, methane and natural gas hydrate are discussed. Gas hydrate particles initially seem to grow mainly in size and at latter stages in number. (EG) EFP-94; 41 refs.

  2. Assessment of surface layer parameters from routine meteorological measurements in the Pannonia region

    Science.gov (United States)

    Popov, Zlatica; Weidinger, Tamás.; Baranka, Györgyi

    2010-05-01

    In this paper, assessment of surface layer parameters (SLP) is discussed, including roughness length, friction velocity, kinematic heat flux, Monin-Obukov length scale (L), etc., through the determination of energy and particle exchange from routine weather observations. Air temperature, total cloud cover, albedo and soil state (or soil moisture, if available) will be used in the calculation of net radiation and sensible heat flux (Holstlag, 1984; Nyren and Gryning, 1999; Foken, 2008). Alternatively, one can use the balance between incoming shortwave and outgoing longwave radiation, parameterized with the low, middle and high level cloud amount, respectively, to obtain net radiation (Stull, 1988). Differences for each method will be investigated. 10 m wind measurement and universal function (after Businger and Dyer, 1974) and effective roughness length (using wind gust data after Verkaik, 1999) and roughness length (which is a function of stability, Kramm, 1989) will be used for the calculation of friction velocity and Monin-Obukhov length scale. Universal functions will be modified for stable case (Beljaars and Holstlag, 1994), and for the free convection case (Steeneveld, Holtslag, Debruin, 2004). Variation of different roughness lengths and universal functions, for different classes of stability will be discussed. SLP obtained from profile measurements, reanalysis or from direct flux measurements, respectively, will be compared. PBL height obtained from SLP (as described Steeneveld, van de Wiel and Holstlag, 2006, for stable case and Gryning and Batchvarova, 1991, or Seibert, Bayrich, Gryning, Joffre, Rasmussen and Tercief, 2004, for unstable case) will be compared to those determined from radiosoundings (Szeged, Hungary) and from the ECMWF reanalysis, respectively. Standard meteorological data set and energy budget component measurements from agro- meteorological observatory of Debrecen and EU6 NitroEurope site of Bugac (Hungary) are used for development and

  3. ß-TCP bone substitutes in tibial plateau depression fractures.

    Science.gov (United States)

    Rolvien, Tim; Barvencik, Florian; Klatte, Till Orla; Busse, Björn; Hahn, Michael; Rueger, Johannes Maria; Rupprecht, Martin

    2017-10-01

    The use of beta-tricalciumphospate (ß-TCP, Cerasorb®) ceramics as an alternative for autologous bone-grafting has been outlined previously, however with no study focusing on both clinical and histological outcomes of ß-TCP application in patients with multi-fragment tibial plateau fractures. The aim of this study was to analyze the long-term results of ß-TCP in patients with tibial plateau fractures. 52 patients were included in this study. All patients underwent open surgery with ß-TCP block or granulate application. After a mean follow-up of 36months (14-64months), the patients were reviewed. Radiography and computed-tomography were performed, while the Rasmussen score was obtained for clinical outcome. Furthermore, seven patients underwent biopsy during hardware removal, which was subsequently analyzed by histology and backscattered electron microscopy (BSEM). An excellent reduction with two millimeters or less of residual incongruity was achieved in 83% of the patients. At follow-up, no further changes occurred and no nonunions were observed. Functional outcome was good to excellent in 82%. Four patients underwent revision surgery due to reasons unrelated to the bone substitute material. Histologic analyses indicated that new bone was built around the ß-TCP-grafts, however a complete resorption of ß-TCP was not observed. ß-TCP combined with internal fixation represents an effective and safe treatment of tibial plateau depression fractures with good functional recovery. While its osteoconductivity seems to be successful, the biological degradation and replacement of ß-TCP is less pronounced in humans than previous animal studies have indicated. Copyright © 2017 Elsevier B.V. All rights reserved.

  4. Waste Feed Delivery System Phase 1 Preliminary RAM Analysis [SEC 1 and 2

    Energy Technology Data Exchange (ETDEWEB)

    DYKES, A.A.

    2000-10-11

    This report presents the updated results of the preliminary reliability, availability, and maintainability (RAM) analysis of selected waste feed delivery (WFD) operations to be performed by the Tank Farm Contractor (TFC) during Phase I activities in support of the Waste Treatment and Immobilization Plant (WTP). For planning purposes, waste feed tanks are being divided into five classes in accordance with the type of waste in each tank and the activities required to retrieve, qualify, and transfer waste feed. This report reflects the baseline design and operating concept, as of the beginning of Fiscal Year 2000, for the delivery of feed from three of these classes, represented by source tanks 241-AN-102, 241-AZ-101 and 241-AN-105. The preliminary RAM analysis quantifies the potential schedule delay associated with operations and maintenance (OBM) field activities needed to accomplish these operations. The RAM analysis is preliminary because the system design, process definition, and activity planning are in a state of evolution. The results are being used to support the continuing development of an O&M Concept tailored to the unique requirements of the WFD Program, which is being documented in various volumes of the Waste Feed Delivery Technical Basis (Carlson. 1999, Rasmussen 1999, and Orme 2000). The waste feed provided to the WTP must: (1) meet limits for chemical and radioactive constituents based on pre-established compositional envelopes (i.e., feed quality); (2) be in acceptable quantities within a prescribed sequence to meet feed quantities; and (3) meet schedule requirements (i.e., feed timing). In the absence of new criteria related to acceptable schedule performance due to the termination of the TWRS Privatization Contract, the original criteria from the Tank Waste Remediation System (77443s) Privatization Contract (DOE 1998) will continue to be used for this analysis.

  5. Assessment and statistics of surgically induced astigmatism.

    Science.gov (United States)

    Naeser, Kristian

    2008-05-01

    The aim of the thesis was to develop methods for assessment of surgically induced astigmatism (SIA) in individual eyes, and in groups of eyes. The thesis is based on 12 peer-reviewed publications, published over a period of 16 years. In these publications older and contemporary literature was reviewed(1). A new method (the polar system) for analysis of SIA was developed. Multivariate statistical analysis of refractive data was described(2-4). Clinical validation studies were performed. The description of a cylinder surface with polar values and differential geometry was compared. The main results were: refractive data in the form of sphere, cylinder and axis may define an individual patient or data set, but are unsuited for mathematical and statistical analyses(1). The polar value system converts net astigmatisms to orthonormal components in dioptric space. A polar value is the difference in meridional power between two orthogonal meridians(5,6). Any pair of polar values, separated by an arch of 45 degrees, characterizes a net astigmatism completely(7). The two polar values represent the net curvital and net torsional power over the chosen meridian(8). The spherical component is described by the spherical equivalent power. Several clinical studies demonstrated the efficiency of multivariate statistical analysis of refractive data(4,9-11). Polar values and formal differential geometry describe astigmatic surfaces with similar concepts and mathematical functions(8). Other contemporary methods, such as Long's power matrix, Holladay's and Alpins' methods, Zernike(12) and Fourier analyses(8), are correlated to the polar value system. In conclusion, analysis of SIA should be performed with polar values or other contemporary component systems. The study was supported by Statens Sundhedsvidenskabeligt Forskningsråd, Cykelhandler P. Th. Rasmussen og Hustrus Mindelegat, Hotelejer Carl Larsen og Hustru Nicoline Larsens Mindelegat, Landsforeningen til Vaern om Synet

  6. Combining cognitive engineering and information fusion architectures to build effective joint systems

    Science.gov (United States)

    Sliva, Amy L.; Gorman, Joe; Voshell, Martin; Tittle, James; Bowman, Christopher

    2016-05-01

    The Dual Node Decision Wheels (DNDW) architecture concept was previously described as a novel approach toward integrating analytic and decision-making processes in joint human/automation systems in highly complex sociotechnical settings. In this paper, we extend the DNDW construct with a description of components in this framework, combining structures of the Dual Node Network (DNN) for Information Fusion and Resource Management with extensions on Rasmussen's Decision Ladder (DL) to provide guidance on constructing information systems that better serve decision-making support requirements. The DNN takes a component-centered approach to system design, decomposing each asset in terms of data inputs and outputs according to their roles and interactions in a fusion network. However, to ensure relevancy to and organizational fitment within command and control (C2) processes, principles from cognitive systems engineering emphasize that system design must take a human-centered systems view, integrating information needs and decision making requirements to drive the architecture design and capabilities of network assets. In the current work, we present an approach for structuring and assessing DNDW systems that uses a unique hybrid DNN top-down system design with a human-centered process design, combining DNN node decomposition with artifacts from cognitive analysis (i.e., system abstraction decomposition models, decision ladders) to provide work domain and task-level insights at different levels in an example intelligence, surveillance, and reconnaissance (ISR) system setting. This DNDW structure will ensure not only that the information fusion technologies and processes are structured effectively, but that the resulting information products will align with the requirements of human decision makers and be adaptable to different work settings .

  7. An observational study on outcome of hemispherotomy in children with refractory epilepsy.

    Science.gov (United States)

    Panigrahi, Manas; Krishnan, Shyam Sundar; Vooturi, Sudhindra; Vadapalli, Rammohan; Somayajula, Shanmukhi; Jayalakshmi, Sita

    2016-12-01

    The current study aimed to evaluate the clinical characteristics and outcome of hemispherotomy in children with refractory hemispherical epilepsy. Retrospective analysis of data in twenty one children aged ≤12 years who underwent hemispherotomy and had at least two years post surgery follow-up was performed. Sixteen children underwent Delalande's vertical para-sagittal hemispherotomy (VPH), while lateral peri-insular functional hemispherotomy was performed in the rest. The average age of onset for epilepsy in the study population was 2.9 ± 2.4 years; the average duration of epilepsy was 4.0 ± 2.9 years. The mean age at surgery of the study population was 6.8 ± 2.8 years. Six (28.5%) children were girls. Gliosis due to presumed childhood infarct was most common etiology, observed in 13 (62.0%) of the children, followed by Rasmussen's encephalitis in six (28.5%). There was no significant difference between the surgery groups for the reported acute post operative seizures (APOS) (20.0% vs. 25.0%; p = 1.000). At last follow up 90.5% patients were seizure free; there was no difference between the groups for seizure freedom (60.0% vs. 87.5%; p = 0.228). When analyzed for outcome between the etiologies, seizure freedom was similar for gliosis due to infarct (76.9%), Rassmussens encephalitis (83.3%) and malformations of cortical development (MCD) (100.0%). Moreover, improved quality of life in epilepsy (QOLIE) scores was observed in 80.0% of the lateral peri-insular functional hemispherotomy group and 87.5% children in VPH group at the last follow-up. Gliosis due to presumed childhood infarct was the leading cause of medically refractory epilepsy caused by hemispheric lesions in the current study. Encouragingly, hemispherotomy offers seizure freedom (in 90.5% patients) and improvement in QOLIE scores at two years follow up. Copyright © 2015 IJS Publishing Group Ltd. Published by Elsevier Ltd. All rights reserved.

  8. The Danish Cerebral Palsy Follow-up Program

    Directory of Open Access Journals (Sweden)

    Rasmussen HM

    2016-10-01

    Full Text Available Helle Mätzke Rasmussen,1,2 Kirsten Nordbye-Nielsen,3 Bjarne Møller-Madsen,3 Mette Johansen,4 Niels Ellitsgaard,5 Charlotte Reinhardt Pedersen,6 Gija Rackauskaite,7 Henriette Engberg,8,9 Niels Wisbech Pedersen2 1Department of Pediatrics, The Danish Cerebral Palsy Follow-up Program, Lillebaelt Hospital, Kolding, 2Department of Orthopedic Surgery and Traumatology, Institute of Clinical Research, Odense University Hospital, University of Southern Denmark, Odense, 3Department of Children's Orthopaedics, Aarhus University Hospital, Institute of Clinical Research, Aarhus University, Aarhus, 4Department of Pediatrics, Aalborg University Hospital, Aalborg, 5Department of Orthopedic Surgery, Hvidovre University Hospital, Hvidovre, 6Department of Pediatrics, North Zealand Hospital Hilleroed, Hilleroed, 7Department of Pediatrics, Aarhus University Hospital, Aarhus, 8Research Unit of Clinical Epidemiology, Institute of Clinical Research, University of Southern Denmark, 9Centre for Clinical Epidemiology, Odense University Hospital, Odense, Denmark Aim of database: The Danish Cerebral Palsy Follow-up Program is a combined follow-up program and national clinical quality database that aims to monitor and improve the quality of health care for children with cerebral palsy (CP. Study population: The database includes children with CP aged 0–15 years and children with symptoms of CP aged 0–5 years. Main variables: In the follow-up program, the children are offered examinations throughout their childhood by orthopedic surgeons, physiotherapists, occupational therapists, and pediatricians. Examinations of gross and fine motor function, manual ability, muscle tone, passive range of motion, use of orthotics, and assistive devices are performed once a year; radiographic examination of the hips is planned based on the child's age and gross motor function; and the diagnosis is performed once before the age of 5 years. Six indicators were developed based on

  9. Holocene sea level, a semi-empirical contemplation

    Science.gov (United States)

    Bittermann, Klaus; Kemp, Andrew; Vermeer, Martin; Rahmstorf, Stefan

    2017-04-01

    , 103, 91-115. Golledge, N.R., Menviel, L., Carter, L., Fogwill, C.J., England, M.H., Cortese, G., & Levy, R.H. 2014. Antarctic contribution to meltwater pulse 1A from reduced Southern Ocean overturning. Nature communications, 5, 5107. Vinther, B.M., Buchardt, S.L., Clausen, H.B., Dahl-Jensen, D., Johnsen, S.J., Fisher, D.A., Koerner, R.M., Raynaud, D., Lipenkov, V., Andersen, K.K., Blunier, T., Rasmussen, S.O., Steffensen, J.P., & Svensson, A.M. 2009. Holocene thinning of the Greenland ice sheet. Nature, 461(7262), 385-388.

  10. Late plasticity for language in a child's non-dominant hemisphere: a pre- and post-surgery fMRI study.

    Science.gov (United States)

    Hertz-Pannier, Lucie; Chiron, Catherine; Jambaqué, Isabelle; Renaux-Kieffer, Virginie; Van de Moortele, Pierre-François; Delalande, Olivier; Fohlen, Martine; Brunelle, Francis; Le Bihan, Denis

    2002-02-01

    The ability of the right hemisphere to sustain the acquisition or the recovery of language after extensive damage to the left hemisphere has been essentially related to the age at the time of injury. Better language abilities are acquired when the insult occurs in early childhood (perinatal insults) compared with later occurrence. However, while previous studies have described the neuropsychological pattern of language development in typical cases, the neural bases of such plasticity remain unexplored. Non-invasive functional MRI (fMRI) is a unique tool to assess the neural correlates of brain plasticity through repeated studies, but the technique has not been widely used in children because of methodological limitations. Plasticity of language was studied in a boy who developed intractable epilepsy related to Rasmussen's syndrome of the left hemisphere at age 5 years 6 months, after normal language acquisition. The first fMRI study at age 6 years 10 months showed left lateralization of language networks during a word fluency task. After left hemispherotomy at age 9 years, the child experienced profound aphasia and alexia, with rapid recovery of receptive language but slower and incomplete recovery of expressive language and reading. Postoperative fMRI at age 10 years 6 months showed a shift of language-related networks to the right during expressive and receptive tasks. Right activation was seen mainly in regions that could not be detected preoperatively, but mirrored those previously found in the left hemisphere (inferior frontal, temporal and parietal cortex), suggesting reorganization in a pre-existing bilateral network. In addition, neuropsychological data of this case support the hypothesis of innately more bilateral distribution of receptive than expressive language. This first serial fMRI study illustrates the great plasticity of the child's brain and the ability of the right hemisphere to take over some expressive language functions, even at a relatively

  11. Developmental History of an Intriguing Peat-Forming Community Along the West Antarctic Peninsula

    Science.gov (United States)

    Loisel, J.; Yu, Z.; Beilman, D.; Kaiser, K.

    2014-12-01

    Permafrost peatbanks along the West Antarctic Peninsula (WAP) have become valuable high-resolution archives for late-Holocene climatic conditions recently. We recently observed and studied a few water-saturated peatlands that had formed in rocky depressions near Vernadsky Station and in mainland Antarctica (~ 65°S, 64°W). Remarkably, we seem to be the very first ones to analyze these systems for environmental reconstructions. The similarity between these peatlands and fens from the lower latitudes is striking, and the rarity of these systems along the WAP is intriguing. We present a high-resolution, multi-proxy record of ecosystem development and paleoenvironmental conditions for Rasmussen peatland. The ecosystem is ~100 m2 in size and is characterized by a shallow water table depth at 7 cm below the surface. Surface vegetation is dominated by Calliergon spp., a wet-adapted moss found along the WAP. The studied moss deposit is 50 cm thick and has a high organic matter content (> 90% dry weight). Plant macrofossil analysis reveals that the peatland was initially a wet Sanionia spp. carpet and that a sharp transition to Calliergon spp. occurred about half way through the deposit. A distinct layer of highly decomposed organic matter was observed from 32 to 40 cm and could indicate a period of slowed peat formation, potentially due to dry conditions (enhanced peat decay) or perennial snow cover (limited plant growth). Biochemical decomposition indicators such as carbohydrate yields, acid:aldehyde ratios of lignin phenols, and hydroxyproline yields are being determined to better understand the extent of peat decay that has occurred at this site throughout its development, particularly to further address the nature of the observed stratigraphic changes. Preliminary results indicate that carbohydrate yields of the bottom half of the core are about 1/3 smaller than those of the top half, indicating substantial carbon loss due to decomposition. Overall, these peatlands

  12. Smoking and renal function in people living with human immunodeficiency virus: a Danish nationwide cohort study

    Directory of Open Access Journals (Sweden)

    Ahlström MG

    2015-08-01

    Full Text Available Magnus Glindvad Ahlström,1 Bo Feldt-Rasmussen,2 Rebecca Legarth,1 Gitte Kronborg,3 Court Pedersen,4 Carsten Schade Larsen,5 Jan Gerstoft,1 Niels Obel1 1Department of Infectious Diseases, 2Department of Nephrology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, 3Department of Infectious Diseases, Copenhagen University Hospital, Hvidovre, 4Department of Infectious Diseases, Odense University Hospital, Odense, 5Department of Infectious Diseases, Aarhus University Hospital, Skejby, Aarhus, Denmark Introduction: Smoking is a main risk factor for morbidity and mortality in people living with human immunodeficiency virus (PLHIV, but its potential association with renal impairment remains to be established. Methods: We did a nationwide population-based cohort study in Danish PLHIV to evaluate the association between smoking status and 1 overall renal function and risk of chronic kidney disease (CKD, 2 risk of any renal replacement therapy (aRRT, and 3 mortality following aRRT. We calculated estimated creatinine clearance using the Cockcroft–Gault equation (CG-CrCl, and evaluated renal function graphically. We calculated cumulative incidence of CKD (defined as two consecutive CG-CrCls of ≤60 mL/min, ≥3 months apart and aRRT and used Cox regression models to calculate incidence rate ratios (IRRs for risk of CKD, aRRT, and mortality rate ratios (MRRs following aRRT. Results: From the Danish HIV Cohort Study, we identified 1,475 never smokers, 768 previous smokers, and 2,272 current smokers. During study period, we observed no association of smoking status with overall renal function. Previous and current smoking was not associated with increased risk of CKD (adjusted IRR: 1.1, 95% confidence interval [CI]: 0.7–1.7; adjusted IRR: 1.3, 95% CI: 0.9–1.8 or aRRT (adjusted IRR: 0.8, 95% CI: 0.4–1.7; adjusted IRR: 0.9, 95% CI: 0.5–1.7. Mortality following aRRT was high in PLHIV and increased in smokers vs never smokers (adjusted MRR: 3

  13. Structure-activity analysis of synthetic alpha-thrombin-receptor-activating peptides.

    Science.gov (United States)

    Van Obberghen-Schilling, E; Rasmussen, U B; Vouret-Craviari, V; Lentes, K U; Pavirani, A; Pouysségur, J

    1993-06-15

    alpha-Thrombin stimulates G-protein-coupled effectors leading to secretion and aggregation in human platelets, and to a mitogenic response in CCL39 hamster fibroblasts. alpha-Thrombin receptors can be activated by synthetic peptides corresponding to the receptor sequence starting with serine-42, at the proposed cleavage site. We have previously determined that the agonist domain of receptor-activating peptides resides within the five N-terminal residues [Vouret-Craviari, Van Obberghen-Schilling, Rasmussen, Pavirani, Lecocq and Pouysségur (1992) Mol. Biol. Cell. 3, 95-102], although the 7-residue peptide (SFFLRNP) corresponding to the hamster alpha-thrombin receptor was 10 times more potent than the 5-residue peptide for activation of human platelets. In the present study we have analysed the role of individual amino acids in receptor activation by using a series of modified hexa- or hepta-peptides derived from the human alpha-thrombin-receptor sequence. Cellular events examined here include phospholipase C activation, adenylyl cyclase inhibition and DNA synthesis stimulation in non-transformed CCL39 fibroblasts and a tumorigenic variant of that line (A71 cells). Modification of the peptide sequence had similar functional consequence for each of the assays described, indicating that either a unique receptor or pharmacologically indistinguishable receptor subtypes activate distinct G-protein signalling pathways. Furthermore, we found that: (1) the N-terminal serine can be replaced by small or intermediately sized amino acids (+/- hydroxyl groups) without loss of activity. However, its replacement by an aromatic side-chain or omission of the N-terminal amino group severely reduces activity. (2) An aromatic side-chain on the penultimate N-terminal residue appears to play a critical role since phenylalanine in this position can be substituted by tyrosine without complete loss of activity whereas an alanine in its place is not tolerated. (3) Deletion of the first

  14. Analysis of mixing-layer height retrieval methods using backscatter lidar returns and microwave-radiometer temperature observations in the context of synergy

    Science.gov (United States)

    Saeed, Umar; Rocadenbosch, Francesc

    2017-04-01

    Mixing Layer Height (MLH) is an important parameter in many different atmospheric and meteorological applications. However, there does not exist a single instrument or method which provides accurate and physically consistent estimates of MLH. Instead, there are several methods for MLH estimation based on the measurements of different atmospheric tracers using different instruments [1, 2]. In this work, MLH retrieval methods using backscattered lidar signals and Microwave Radiometer (MWR)-retrieved potential-temperature profiles are compared in terms of their associated uncertainties. The Extended Kalman Filter (EKF) is used for MLH retrieval from backscattered lidar signals [3] and parcel method [4] is used for MLH retrieval from MWR-retrieved potential-temperature profiles. Measurement and retrieval errors are revisited and incorporated into the MLH estimation methods used. Uncertainties on MLH estimates from the two methods are compared along with a combined MLH-retrieval discussion case. The uncertainty analysis is validated using long-term lidar and MWR measurement data, under different atmospheric conditions, from the HD(CP)2 Observational Prototype Experiment (HOPE) campaign at Jülich, Germany [5]. MLH estimates from a Doppler wind lidar and radiosondes are used as reference. This work has received funding from the European Union Seventh Framework Programme, FP7 People, ITN Marie Curie Actions Programme (2012-2016) in the frame of ITaRS project (GA 289923), H2020 programme under ACTRIS-2 project (GA 654109), the Spanish Ministry of Economy and Competitiveness - European Regional Development Funds under TEC2015-63832-P project, and from the Generalitat de Catalunya (Grup de Recerca Consolidat) 2014-SGR-583. [1] S. Emeis, Surface-based Remote Sensing of the Atmospheric Boundary Layer. 978-90-481-9339-4, Springer, 2010. [2] P. Seibert, F. Beyrich, S.-E. Gryning, S. Joffre, A. Rasmussen, and P. Tercier, "Review and intercomparison of operational methods for the

  15. Monitoring marine heavy metal contamination via the chemical analysis of foraminifera and growth increments in bivalves - a pilot study from a Pb and Zn mining region in western Greenland

    Science.gov (United States)

    Jessen, C.; Asmund, G.; Elberling, B.; Frei, D.; Knudsen, C.; Rasmussen, P.

    2011-12-01

    Annual monitoring of heavy metal concentrations in the fjords (sea water, seaweed, lichens, blue mussels, shorthorn sculpin and Northern prawn) adjacent to the Black Angel lead-zinc mine (active 1973-1990) at Maarmorilik, western Greenland was initiated during operation of the mine and continues through to today. This pilot study tests whether the calcareous shells of bivalves and foraminifera register these known variations in heavy metal concentrations. Live individuals of Mytilus edulis were collected through a transect of monitoring stations in 2009 and PB-Zn concentrations were measured at multiple points within the yearly increments using LA-ICP-MS. Individuals aged between 12 and 28 years were measured and demonstrated a clear signal of mine closure even at 40 km distance from the plant. Foraminifera (Melonis barleeanus) from a sediment core dating from 1880 AD to present have previously been shown to display a greater percentage of deformities during the period of mining activity (Elberling et al. 2003) possibly suggesting a correlation between heavy metal concentrations in sea water and morphological development. LA-ICP-MS analysis of individual foraminifera confirms an increase in Pb-Zn uptake during mining operations. Although it could therefore be expected that Pb-Zn concentrations would be enhanced in the 'deformed' foraminifera relative to the 'non-deformed', no difference in Pb-Zn was concentrations was detected. This short pilot study (Jessen et al.2010) demonstrates the potential of calcareous material as indicators of environmental pollution and their applicability as a monitoring tool in remote regions. Jessen CA, Asmund G, Elberling B, Frei D, Knudsen C and Rasmussen P. 2010 Monitoring marine heavy metal contamination via the chemical analysis of growth increments in bivalves - a pilot study. Danmarks og Grønlands Geologiske Undersøgelse Rapport 2010/86. 1-20 Elberling, B., Knudsen, K. L., Kristensen, P. H., and Asmund, G. (2003) Applying

  16. Australian thrips of the Haplothrips lineage (Insecta: Thysanoptera)

    Energy Technology Data Exchange (ETDEWEB)

    Mound, Laurence A.; Minaei, Kambiz

    2007-12-01

    Water is important and ubiquitous and surprisingly not understood. Just because is it common, does not mean its understood "Poets say science takes away from the beauty of the stars-mere globs of gas atoms. I too can see the stars on a desert night, and feel them. But do I see less or more? ... What is the pattern, or the meaning, or the why? It does not do harm to the mystery to know a little about it. For far more marvelous is the truth than any artists of the past imagined it." - Richard P. Feynman, The Feynman Lectures on Physics, 1963. (Cited in the introduction to Chapter 3 of "The Snowflake, Winter's Secret Beauty, Text by Kenneth Libbrecht, Photography by Patricia Rasmussen.) 1. Highlight the fact that water is still one of the most active and challenging research areas in chemistry and physics 2. Describe in general terms why water is unique from the point of view of its properties o Large dipole-moment o Very polarizable o Involved in is own chemistry (e.g. auto ionization defining the pH scale) • Atomic view: o Oxygen and Hydrogen. o Hydrogen is a quantum mechanical in nature. Classical physics is no good. o Water’s Charge-charge interaction described by classical physics laws (e.g. Coulomb) o The statistical mechanics of water. Why counting is important. o You need the full arsenal of theoretical methods to understand water • Waters well known bulk properties do not explain waters anomalies o Surface tension, heat capacity • Understanding the microscopic nature of water and how this gives rise to the known bulk quantities is the thrust of state-of-the-art research o Hydrogen bonding o Liquid structure o The so-called “spherical cow” model gets you no where with water o There are 10s-100s of different water models available in the scientific literature. It is a hard business • All of life takes place at the interfaces of solid, liquid, and gas o Biology takes advantage of waters varying properties in different geometries (e.g. confined

  17. Sociodemographic characteristics of nonparticipants in the Danish colorectal cancer screening program: a nationwide cross-sectional study

    Directory of Open Access Journals (Sweden)

    Larsen MB

    2017-06-01

    Full Text Available Mette Bach Larsen,1 Ellen M Mikkelsen,2 Morten Rasmussen,3 Lennart Friis-Hansen,4 Anders U Ovesen,5 Hans Bjarke Rahr,6 Berit Andersen1 1Department of Public Health Programmes, Randers Regional Hospital, Central Denmark Region, Randers NO, 2Department of Clinical Epidemiology, Aarhus University Hospital, Central Denmark Region, Aarhus N, 3Digestive Disease Center K, Bispebjerg Hospital, The Capital Region of Denmark, Copenhagen NV, 4Department of Clinical Biochemistry, Nordsjællands Hospital, The Capital Region of Denmark, Hillerød, 5Department of Surgical Gastroenterology, Aalborg University Hospital, North Denmark Region, Aalborg, 6Department of Surgery, Vejle Hospital, Region of Southern Denmark, Vejle, Denmark Introduction: Fecal occult blood tests are recommended for colorectal cancer (CRC screening in Europe. Recently, the fecal immunochemical test (FIT has come into use. Sociodemographic differences between participants and nonparticipants may be less pronounced when using FIT as there are no preceding dietary restrictions and only one specimen is required. The aim of this study was to examine the associations between sociodemographic characteristics and nonparticipation for both genders, with special emphasis on those who actively unsubscribe from the program. Methods: The study was a national, register-based, cross-sectional study among men and women randomized to be invited to participate in the prevalence round of the Danish CRC screening program between March 1 and December 31, 2014. Prevalence ratios (PRs were used to quantify the association between sociodemographic characteristics and nonparticipation (including active nonparticipation. PRs were assessed using Poisson regression with robust error variance.Results: The likelihood of being a nonparticipant was highest in the younger part of the population; however, for women, the association across age groups was U-shaped. Female immigrants were more likely to be

  18. Searching for the right scale in catchment hydrology: the effect of soil spatial variability in simulated states and fluxes

    Science.gov (United States)

    Baroni, Gabriele; Zink, Matthias; Kumar, Rohini; Samaniego, Luis; Attinger, Sabine

    2017-04-01

    .g., finer resolution input. For this reason, the integration in this analysis of all the relevant input factors (e.g., precipitation, vegetation, geology) could provide a strong support for the definition of the right scale for each specific model application. In this context, however, the main challenge for a proper model assessment will be the correct characterization of the spatio- temporal variability of each input factor. Refsgaard, J.C., Højberg, A.L., He, X., Hansen, A.L., Rasmussen, S.H., Stisen, S., 2016. Where are the limits of model predictive capabilities?: Representative Elementary Scale - RES. Hydrol. Process. doi:10.1002/hyp.11029

  19. Characterization of the N-Acetyl-[alpha]-d-glucosaminyl l-Malate Synthase and Deacetylase Functions for Bacillithiol Biosynthesis in Bacillus anthracis

    Energy Technology Data Exchange (ETDEWEB)

    Parsonage, Derek; Newton, Gerald L.; Holder, Robert C.; Wallace, Bret D.; Paige, Carleitta; Hamilton, Chris J.; Dos Santos, Patricia C.; Redinbo, Matthew R.; Reid, Sean D.; Claiborne, Al (Wake Forest); (UNC); (East Anglia); (UCSD)

    2012-02-21

    Bacillithiol (Cys-GlcN-malate, BSH) has recently been identified as a novel low-molecular weight thiol in Bacillus anthracis, Staphylococcus aureus, and several other Gram-positive bacteria lacking glutathione and mycothiol. We have now characterized the first two enzymes for the BSH biosynthetic pathway in B. anthracis, which combine to produce {alpha}-D-glucosaminyl L-malate (GlcN-malate) from UDP-GlcNAc and L-malate. The structure of the GlcNAc-malate intermediate has been determined, as have the kinetic parameters for the BaBshA glycosyltransferase ({yields}GlcNAc-malate) and the BaBshB deacetylase ({yields}GlcN-malate). BSH is one of only two natural products reported to contain a malyl glycoside, and the crystal structure of the BaBshA-UDP-malate ternary complex, determined in this work at 3.3 {angstrom} resolution, identifies several active-site interactions important for the specific recognition of L-malate, but not other {alpha}-hydroxy acids, as the acceptor substrate. In sharp contrast to the structures reported for the GlcNAc-1-D-myo-inositol-3-phosphate synthase (MshA) apo and ternary complex forms, there is no major conformational change observed in the structures of the corresponding BaBshA forms. A mutant strain of B. anthracis deficient in the BshA glycosyltransferase fails to produce BSH, as predicted. This B. anthracis bshA locus (BA1558) has been identified in a transposon-site hybridization study as required for growth, sporulation, or germination [Day, W. A., Jr., Rasmussen, S. L., Carpenter, B. M., Peterson, S. N., and Friedlander, A. M. (2007) J. Bacteriol. 189, 3296-3301], suggesting that the biosynthesis of BSH could represent a target for the development of novel antimicrobials with broad-spectrum activity against Gram-positive pathogens like B. anthracis. The metabolites that function in thiol redox buffering and homeostasis in Bacillus are not well understood, and we present a composite picture based on this and other recent work.

  20. Effect of endurance versus resistance training on quadriceps muscle dysfunction in COPD: a pilot study

    Directory of Open Access Journals (Sweden)

    Iepsen UW

    2016-10-01

    Full Text Available Ulrik Winning Iepsen,1 Gregers Druedal Wibe Munch,1 Mette Rugbjerg,1 Anders Rasmussen Rinnov,1 Morten Zacho,1 Stefan Peter Mortensen,1,2 Niels H Secher,3 Thomas Ringbaek,4 Bente Klarlund Pedersen,1 Ylva Hellsten,5 Peter Lange,1,4,6 Pia Thaning1,4 1The Centre of Inflammation and Metabolism and the Centre for Physical Activity Research, Rigshospitalet, University of Copenhagen, Denmark, 2Department of Cardiovascular and Renal Research, University of Southern Denmark, Odense, 3Department of Anesthesiology, University of Copenhagen, Rigshospitalet, Copenhagen, 4Department of Respiratory Medicine, University Hospital Hvidovre, Hvidovre, 5Department of Nutrition, Exercise and Sports, University of Copenhagen, 6Department of Public Health, Section of Social Medicine, University of Copenhagen, Copenhagen, Denmark Introduction: Exercise is an important countermeasure to limb muscle dysfunction in COPD. The two major training modalities in COPD rehabilitation, endurance training (ET and resistance training (RT, may both be efficient in improving muscle strength, exercise capacity, and health-related quality of life, but the effects on quadriceps muscle characteristics have not been thoroughly described.Methods: Thirty COPD patients (forced expiratory volume in 1 second: 56% of predicted, standard deviation [SD] 14 were randomized to 8 weeks of ET or RT. Vastus lateralis muscle biopsies were obtained before and after the training intervention to assess muscle morphology and metabolic and angiogenic factors. Symptom burden, exercise capacity (6-minute walking and cycle ergometer tests, and vascular function were also assessed.Results: Both training modalities improved symptom burden and exercise capacity with no difference between the two groups. The mean (SD proportion of glycolytic type IIa muscle fibers was reduced after ET (from 48% [SD 11] to 42% [SD 10], P<0.05, whereas there was no significant change in muscle fiber distribution with RT. There was

  1. The impact of quality of life on treatment preferences in multiple sclerosis patients

    Directory of Open Access Journals (Sweden)

    Lee Mortensen G

    2017-10-01

    Full Text Available Gitte Lee Mortensen,1 Peter V Rasmussen2 1Medical Anthropology Department, AnthroConsult, 2Department of Neurology, University Hospital of Aarhus, Aarhus C, Denmark Introduction: Multiple sclerosis (MS is a demyelinating disorder with an unpredictable and often disabling course. MS symptoms are very heterogeneous and may lead to reduced physical, cognitive, and psychosocial functioning decreasing patients’ quality of life (QoL. Today, various disease-modifying treatments (DMTs may prevent disease progression. However, it is increasingly complex to select the right therapy for a given patient and patient preferences should be considered when making treatment decisions. This study aimed to explore the main factors affecting patients’ preferences regarding MS treatment and health care.Methods: Five qualitative focus group interviews were carried out with a total of 40 participants from across Denmark. A semistructured question guide included questions that were identified in a systematic literature study about QoL and treatment preferences in patients with MS. The participants were asked to describe their disease experiences, their health-related QoL, and reasons behind their preferences with regard to treatment and care. The data were analyzed using content analysis and a constructivist approach.Results: The participants’ physical, cognitive, and psychosocial QoL and functioning were reduced by disease symptoms, treatment side effects, and mode of administration. Their ability to uphold meaningful role functioning was crucial to their treatment priorities. The preeminence of anticipated efficacy, ie, the patients’ hope that DMT might prevent disease deterioration in the future, was modified by their present QoL and functioning when ultimately framing their treatment preferences. There was an unmet information and support need from neurology clinics, particularly at the time of diagnosis.Conclusion: The participants’ treatment preferences

  2. Before the Ring: synthesis of linear organic molecules in astrophysical ices by low energy electron impact

    Science.gov (United States)

    Huels, Michael A.; Bass Andrew, D.; Mirsaleh-Kohan, Nasrin; Sanche, Leon

    The question of the origin for the building blocks of life, either synthesized here on earth, or in space [1], has been the subject of much debate, experimental investigation, or astronomical observation, much of it stimulated by the early experiments of Miller [2], and subsequent space radiation related variations thereof [3-5]. And while the precise details of the formation of even the simplest biomolecules that make up life on earth still remain shrouded inmystery, one of the notions that persist throughout the debate is that the building blocks of life, such as amino-acids, or even the cyclic components of RNA and DNA, or other cyclic hydrocarbons (e.g. PHAs), where synthesized via radiolysis [6] either in the earths proto-atmosphere, its early oceans, or in the near interstellar space surrounding the early earth. Here we provide experimental evidence for the hypothesis that interactions of low energy secondary electrons and ions, formed during the radiolysis of matter, with atoms and molecules in the medium, may have played, and may still play an important role in the chemical transformation of astrophysical or planetary surface ices [7], where they lead to the synthesis of more complex chemical species from less complex, naturally occurring components. We report the synthesis and desorption of new chemical species from simple molecular surface ices, containing CH4 / CD4 , C2 D2 , O2 , CO, CO2 , or N2 in various combination mixtures, irradiated by low energy (life's most basic cyclic molecular components in planetary, or astrophysical surface ices that are continuously subjected to the types of space radiations (UV, X-or -ray, or heavy ions) that can generate such low energy secondary electrons. [Funded by NSERC and Canadian Space Agency] [1] P. Ehrenfreund, S. Rasmussen, J. Cleaves, L. Chen, Astrobiology 6 (2006) 490. [2] (a) S.L. Miller, Science 117 (1953) 528; (b) S.L. Miller, J. Am. Chem. Soc. 77 (1955) 2351. [3] (a) M.H. Morre, R.L. Hudson, Icarus 140

  3. Preliminary Results from the AIDP-2 and AIDP-3 Drill Cores Hint at Systematic Mo Enrichments in the ~2.65 Ga Roy Hill Shale

    Science.gov (United States)

    Roy, M.; Ostrander, C. M.; Lyons, T. W.; Olson, S. L.; Buick, R.; Anbar, A. D.

    2014-12-01

    obtaining additional complementary datasets including Fe-speciation, TOC, and traditional and non-traditional isotopes. These data will provide the additional constraints needed to understand the origin and significance of Mo enrichments in these Archean sediments. [1] Rasmussen & Fletcher (2010) Geology, 38: 299-302 [2] Scott et al. (2011) Geology, 39:119-122.

  4. Shillapoo Wildlife Area 2007 Follow-up HEP Report.

    Energy Technology Data Exchange (ETDEWEB)

    Ashley, Paul R.

    2008-03-01

    In April and May 2007 the Regional HEP Team (RHT) conducted a follow-up HEP analysis on the Egger (612 acres) and Herzog (210 acres) parcels located at the north end of the Shillapoo Wildlife Area. The Egger and Herzog parcels have been managed with Bonneville Power Administration funds since acquired in 1998 and 2001 respectively. Slightly more than 936 habitat units (936.47) or 1.14 HUs per acre was generated as an outcome of the 2007 follow-up HEP surveys. Results included 1.65 black-capped chickadee HUs, 280.57 great blue heron HUs, 581.45 Canada goose HUs, 40 mallard HUs, and 32.80 mink HUs. Introduction A follow-up Habitat Evaluation Procedures (HEP) (USFWS 1980) analysis was conducted by the Columbia Basin Fish and Wildlife Authority's (CBFWA) Regional HEP Team (RHT) during April and May 2007 to document changes in habitat quality and to determine the number of habitat units (HUs) to credit Bonneville Power Administration (BPA) for providing operation and maintenance (O&M) funds since WDFW acquired the parcels. The 2007 follow-up HEP evaluation was limited to Shillapoo Wildlife Area (SWA) parcels purchased with Bonneville Power Administration funds. D. Budd (pers. comm.) reported WDFW purchased the 612 acre Egger Farms parcel on November 2, 1998 for $1,737,0001 and the 210 acre Herzog acquisition on June 21, 2001 for $500,000 with Memorandum of Agreement funds (BPA and WDFW 1996) as partial fulfillment of BPA's wildlife mitigation obligation for construction of Bonneville and John Day Dams (Rasmussen and Wright 1989). Anticipating the eventual acquisition of the Egger and Herzog properties, WDFW conducted HEP surveys on these lands in 1994 to determine the potential number of habitat units to be credited to BPA. As a result, HEP surveys and habitat unit calculations were completed as much as seven years prior to acquiring the sites. The term 'Shillapoo Wildlife Area' will be used to describe only the Herzog and Egger parcels in this

  5. Technical Actions, Heart Rate, and Locomotor Activity in 7v7 and 8v8 Games for Female Youth Soccer Players.

    Science.gov (United States)

    Ørntoft, Christina; Larsen, Malte N; Andersen, Thomas B; Rasmussen, Lasse S; Póvoas, Susana C A; Randers, Morten B; Krustrup, Peter

    2016-12-01

    Ørntoft, C, Larsen, MN, Andersen, TB, Rasmussen, LS, Póvoas, SCA, Randers, MB, and Krustrup, P. Technical actions, heart rate, and locomotor activity in 7v7 and 8v8 games for female youth soccer players. J Strength Cond Res 30(12): 3298-3303, 2016-The purpose of this study was to evaluate technical performance, heart rate (HR), and activity profile in 7v7 and 8v8 soccer games for 9- to 10-year-old girls (U11). A total of 24 female youth players participated in the study, all playing 20-minute 7v7 and 8v8 games with 160 and 223 m per player, respectively. Technical actions, HR, and activity profile were measured during the games using video filming, HR monitors, and 5-Hz Global positioning system (GPS) units. The number of technical actions was higher in 7v7 than in 8v8 games (34 ± 19 vs. 28 ± 14; p = 0.03; d = 0.37), as was the number of successful actions (25 ± 16 vs. 20 ± 12; p = 0.01; d = 0.35), with no difference in success rate for technical actions (70 ± 13 vs. 69 ± 14%; p = 0.63; d = 0.07). No differences were found between 7v7 and 8v8 in total distance covered (1,574 ± 251 and 1,622 ± 281 m; p = 0.66; d = 0.18), peak speed (19.5 ± 2.6 and 20.7 ± 1.5 km·h; p = 0.16; d = 0.56), mean HR values (85 ± 5 and 86 ± 6%HRpeak; p = 0.85; d = 0.18), and time of >90% HRpeak (37 ± 16 and 35 ± 14% of playing time; p = 0.70; d = 0.13). Distance covered at the highest running speeds of >16 km·h was lower in 7v7 than in 8v8 games (34 ± 24 vs. 63 ± 34 m; p = 0.018; d = 0.98), as was the number of entries into this speed zone (8 ± 5 vs. 13 ± 7; p = 0.006; d = 0.82). In conclusion, more technical actions and successful actions were observed in 7v7 than in 8v8 games, but players covered more ground with high-speed running in 8v8 games. This study also revealed that HR values were high in both game formats for U11 adolescent female players, with no difference between formats.

  6. Positive predictive value and completeness of prenatally assigned International Classification of Disease-10 kidney anomaly diagnoses in the Danish National Patient Registry

    Directory of Open Access Journals (Sweden)

    Rasmussen M

    2016-01-01

    Full Text Available Maria Rasmussen,1 Morten Smærup Olsen,2 Lone Sunde,1,3 Lars Pedersen,2 Olav Bjørn Petersen4 1Department of Clinical Genetics, Aarhus University Hospital, Skejby, 2Department of Clinical Epidemiology, Aarhus University Hospital, Skejby, 3Department of Biomedicine, Aarhus University, Aarhus, 4Department of Gynecology and Obstetrics, Aarhus University Hospital, Skejby, Denmark Objective: Restricting studies of severe congenital malformations to live-born children may introduce substantial bias. In this study, we estimated the attendance to the second-trimester fetal malformation screening program. We also estimated the positive predictive value (PPV of prenatally assigned International Classification of Disease-10 diagnoses recorded in the Danish National Patient Registry (DNPR and the completeness of case registration. We used kidney anomalies as an example. Methods: We identified the proportion of all Danish live-born children from January 1, 2007 to December 31, 2012, who were scanned during the second trimester using the DNPR and the Civil Registration System. Details of all fetuses with specific kidney anomaly diagnoses according to the DNPR were retrieved. The PPV was estimated using the nationwide Astraia database of pregnancy medical charts or traditional medical charts, as gold standard. The completeness was assessed using the total number of cases estimated by the capture–recapture method. Results: Of 372,263 live born infants, 97.3% were scanned during the second trimester. We identified 172 fetuses in the DNPR. Of these, 149 had kidney anomalies according to Astraia or medical chart review, corresponding to a PPV of 87% (95% CI: 81%–91%. The estimated completeness was 43% (95% CI: 38%–49% for the DNPR and 75% (95% CI: 70%–79% for Astraia. Conclusion: Almost all live-born children were scanned during the second trimester in Denmark. However, low completeness may hamper the use of the DNPR for studies of prenatally detected

  7. Cognitive engineering models in space systems

    Science.gov (United States)

    Mitchell, Christine M.

    1993-01-01

    NASA space systems, including mission operations on the ground and in space, are complex, dynamic, predominantly automated systems in which the human operator is a supervisory controller. Models of cognitive functions in complex systems are needed to describe human performance and form the theoretical basis of operator workstation design, including displays, controls, and decision aids. Currently, there several candidate modeling methodologies. They include the Rasmussen abstraction/aggregation hierarchy and decision ladder, the goal-means network, the problem behavior graph, and the operator function model. The research conducted under the sponsorship of this grant focuses on the extension of the theoretical structure of the operator function model and its application to NASA Johnson mission operations and space station applications. The initial portion of this research consists of two parts. The first is a series of technical exchanges between NASA Johnson and Georgia Tech researchers. The purpose is to identify candidate applications for the current operator function model; prospects include mission operations and the Data Management System Testbed. The second portion will address extensions of the operator function model to tailor it to the specific needs of Johnson applications. At this point, we have accomplished two things. During a series of conversations with JSC researchers, we have defined the technical goal of the research supported by this grant to be the structural definition of the operator function model and its computer implementation, OFMspert. Both the OFM and OFMspert have matured to the point that they require infrastructure to facilitate use by researchers not involved in the evolution of the tools. The second accomplishment this year was the identification of the Payload Deployment and Retrieval System (PDRS) as a candidate system for the case study. In conjunction with government and contractor personnel in the Human-Computer Interaction Lab

  8. Magnetotelluric investigation of the Toender area, Denmark. ALTKUL project report part 2

    Energy Technology Data Exchange (ETDEWEB)

    Rasmussen, T.M.; Thorning, L. [GEUS, Copenhagen (Denmark); Pedersen, L.B.; Shan, C. [Uppsala Univ., Dept. of Earth Sciences, Uppsala (Sweden)

    2012-10-15

    Project ALTKUL was commissioned by DONG E and P A/S and Nordsoefonden; the Danish Energy Agency followed the project closely. The first part of the study has been reported in Rasmussen and Thorning (2012).The starting point of the study was a need for more knowledge on methods that could be used for hydrocarbon exploration in Danish onshore areas, as an alternative to seismic investigations, when these cannot be used for nature protecting reasons. DONG E and P A/S and Nordsoefonden approached GEUS, suggesting a study of seven different non-seismic methods. The Danish Energy Agency was interested in the subject and requested that an actual test of a method be carried out as a part of the project. The optimum choice for a field test was an electromagnetic experiment with a galvanic controlled source (Rasmussen and Thorning, 2012). However, due to organisational issues and a limited timeframe of the project, the final choice of method for the field test was settled on using the magnetotelluric method (MT). Though MT does not utilise galvanic controlled sources, and hence does not serve as a tool for direct hydrocarbon exploration, MT has been used in the past in relation with hydrocarbon exploration onshore and has recently gained considerable interest in China. A contract was entered with Uppsala University for some initial tests of the magnetotelluric (MT) method. The test was carried out August 2012 in an area around Toender, and is reported here as ALTKUL Project Report Part 2. In total 42 MT stations were measured in a 180 km{sup 2} area. The digital data are enclosed with the report and hereby released to the public. A 3D model of the electrical resistivity variations to a depth of 6 km constitutes, together with the actual measured data, the main results of part 2 of the ALTKUL project. The 3D model was derived from an unconstrained 3D inversion of the MT data. The MT data show that pronounced lateral resistivity variations exist at the depth of interest for

  9. Geoethics disgraced by Copernicus in its desperate act of covering up for the IPCC

    Science.gov (United States)

    Mörner, Nils-Axel

    2014-05-01

    All my life I have put observational facts in the centre. This is what Leonardo da Vinci called "to read the book of mother Earth". For a geologist this is very natural because this is the core of the geological profession. The IPCC, on the other hand, put all credits on models and scenarios. One of its founders and its first president, Bert Bolin, at a debate in the Geophysical Society of Sweden in 2001, admitted (quotation): "you can order whatever scenario you wish". With this as a background, we can put a recent action by Copernicus at a test with respect to geoethics and normal decency. The idea that the planetary motions affect and control the solar variability is old, but in the stage of an unproven hypothesis. In recent years major advancements have occurred and in 2013, it seemed that time was ripe for a major, multi-authored, reinvestigation. Therefore, a Special Issue of Pattern Recognition in Physics was devoted to: "Pattern in solar variability, their planetary origin and terrestrial impacts". The volume includes 12 separate research papers and General Conclusions, co-authored by 19 prominent scientists. Indeed, they agreed that the driving factor of solar variability must emerge from the planetary beat on the Sun, and by that its emission of luminosity and Solar Wind both factors of which affect the Earth-Moon system. This may be held as a benchmark event in our understanding of the planetary-solar-terrestrial interaction. Furthermore, they noted two implications of this: partly that the old hypothesis was now lifted to a firm theory, maybe even a new paradigm, and partly that we are on our way into a new grand solar minimum which "sheds serious doubts on the issue of a continued, even accelerated, warming as claimed by the IPCC". "We were alarmed by the second implication", Martin Rasmussen, VD of Copernicus, stated, and took the unbelievable decision immediately to close down the entire journal. This happened on January 17 without any discussion

  10. Detection of Hot Halo Gets Theory Out of Hot Water

    Science.gov (United States)

    2006-02-01

    intergalactic gas," said Jesper Rasmussen of the University of Birmingham, United Kingdom and a coauthor of the report. "What we found is in good agreement with computer simulations in which galaxies are built up gradually from the merger of smaller clouds of hot gas and dark matter." The computer simulations were done by Jesper Sommer-Larsen (also a coauthor of the report) and collaborators at the University of Copenhagen. The paper describing these results will be published in the April issue of the journal New Astronomy. Other researchers on this project were Sune Toft, Yale University; Andrew Benson, University of Oxford, United Kingdom; and Richard Bower, University of Durham, United Kingdom. NASA's Marshall Space Flight Center, Huntsville, Ala., manages the Chandra program for the agency's Science Mission Directorate. The Smithsonian Astrophysical Observatory controls science and flight operations from the Chandra X-ray Center in Cambridge, Mass. http://chandra.harvard.edu and http://chandra.nasa.gov

  11. Downscaling the Local Weather Above Glaciers in Complex Topography

    Science.gov (United States)

    Horak, Johannes; Hofer, Marlis; Gutmann, Ethan; Gohm, Alexander; Rotach, Mathias

    2017-04-01

    evaluation is based on determining the added value of the ICAR simulations - with ERAI output as a reference - in representing the local-scale weather measured at several automatic weather stations. For precipitation amount in particular, data by the Global Precipitation Measurement project are used in a fuzzy verification approach. The results indicate that ICAR provides added value for the Southern Alps of New Zealand in the case of precipitation and relative humidity, for the Cordillera Blanca and the European Alps for wind speed and, at certain locations in the European Alps, for precipitation. In order to more comprehensively investigate the physical plausibility of skill obtained for specific weather situations, the spatio-temporal evolution of the wind field resulting from the ICAR dynamics is analysed for individual case studies. To the authors knowledge this is the first study that specifically investigates the multi-variable consistency of ICAR for different climates, an important prerequisite for all applications which require multi-variable or multi-site input. References: Gutmann, E., Barstad, I., Clark, M., Arnold, J., and Rasmussen, R. (2016). The Intermediate Complexity Atmospheric Research Model (ICAR). Journal of Hydrometeorology, 17(3), 957-973.

  12. Circum-Arctic mapping project: new magnetic anomaly map of the Arctic (to 60 degrees N)

    Science.gov (United States)

    Gaina, Carmen

    2010-05-01

    An international effort to compile Circum-Arctic geophysical and bedrock data has been conducted by several national agencies (Russia-VSEGEI and VNIIO, Sweden-SGU, Finland-GTK, Denmark-GEUS, USA-USGS, Canada-GSC, Germany-BGR and Norway-NGU) since 2005. This project aims to produce an atlas that will comprise geological and geophysical digital maps at a scale of 1: 5 million scale for the Arctic region limited by the 60 degree North latitude. New published and classified magnetic anomaly gridded data from each participant group were gathered and converted to a common datum (WGS84) and format. The Greenland region magnetic anomaly grid (Verhoef et al., 1996) has been updated with new aeromagnetic surveys performed in West Greenland between 1992-2001 (Rasmussen, 2002), and in the Nares Strait area (Damaske & Oakey, 2006; Oakey & Damaske, 2006). The oceanic area east of Greenland (NE Atlantic) contains most of the aeromagnetic data used in the Verhoef et al., (1996)'s compilation (pre-1990) plus new aeromagnetic surveys over offshore Norway collected up to 2007 (Olesen et al., 1997; Olesen et al., 2007; Gernigon et al., 2008). The gridded data has been upward continued to 1 km above ground or sea-level and trimmed around the areas of major overlaps. The Alaska USGS aeromagnetic compilation has been used as the "master grid" for merging the major gridded data sets together and the downward continued lithospheric magnetic field model MF6 derived from satellite data (Maus et al., 2008) has been used as a regional reference surface. We have used a blending function over the area of overlap in order to smooth the transition from one grid to the other (GridKnit, GEOSOFT). The resulting grid has been re-sampled to a 2 km grid cell. In order to construct the final Circum-Arctic magnetic anomaly grid (CAMP-M) we have adopted the approach used by several research groups for compiling the World Digital Magnetic Anomaly Map (WDMAM) and used near-surface magnetic data for the short

  13. A Holocene temperature reconstruction from northern New Zealand: a test of North Atlantic Holocene climate patterns as a global template

    Science.gov (United States)

    van den Bos, Valerie; Rees, Andrew; Newnham, Rewi; Augustinus, Paul

    2017-04-01

    : Alloway, B.V., Lowe, D.J., Barrell, D.J.A., Newnham, R.M., Almond, P.C., Augustinus, P.C., Bertler, N.A.N., Carter, L., Litchfield, N.J., McGlone, M.S., Shulmeister, J., Vandergoes, M.J., Williams, P.W., and NZ-INTIMATE members. 2007. Towards a climate event stratigraphy for New Zealand over the past 30 000 years (NZ-INTIMATE project). Journal of Quaternary Science, 22, 9-35. Dieffenbacher-Krall, A.C., Vandergoes, M.J., Denton, G.H. 2007. An inference model for mean summer air temperatures in the Southern Alps, New Zealand, using subfossil chironomids. Quaternary Science Reviews, 26, 2587-2504. Walker, M.J.C., Berkelhammer, M., Björck, S., Cwynar, L.C., Fisher, D.A., Long, A.J., Lowe, D.J., Newnham, R.M., Rasmussen, S.O., Weiss, H. 2012. Formal subdivision of the Holocene Series/Epoch: a discussion paper by a working group of INTIMATE (Integration of ice-core, marine and terrestrial records) and the Subcommission on Quaternary Stratigraphy (International Commission on Stratigraphy). Journal of Quaternary Science, 27, 649-659.

  14. Optimal management of ADHD in older adults

    Directory of Open Access Journals (Sweden)

    Torgersen T

    2016-01-01

    Full Text Available Terje Torgersen,1,2 Bjorn Gjervan,2,3 Michael B Lensing,4 Kirsten Rasmussen5,6 1Department of Østmarka, St Olav’s Hospital, 2Department of Neuroscience, Norwegian University of Science and Technology, Trondheim, 3Department of Psychiatry, Helse Nord-Trondelag Hospital Trust, Kirkegata, Levanger, 4NevSom, Norwegian Center of Expertise for Neurodevelopmental Disorders and Hypersomnias, Women and Children’s Division, Oslo University Hospital, Oslo, 5St Olav’s Hospital, Broset Center for Research and Education in Forensic Psychiatry, Trondheim, 6Department of Psychology, Norwegian University of Science and Technology, Trondheim, Norway Background: The manifestation of attention-deficit/hyperactivity disorder (ADHD among older adults has become an interesting topic of interest due to an increasing number of adults aged 50 years and older (≥50 years seeking assessment for ADHD. Unfortunately, there is a lack of research on ADHD in older adults, and until recently only a few case reports existed.Method: A systematic search was conducted in the databases Medline/PubMed and PsycINFO in order to identify studies regarding ADHD in adults ≥50 years.Results: ADHD persists into older ages in many patients, but the prevalence of patients fulfilling the criteria for the diagnosis at age ≥50 years is still unknown. It is reason to believe that the prevalence is falling gradually with age, and that the ADHD symptom level is significantly lower in the age group 70–80 years than the group 50–60 years. There is a lack of controlled studies of ADHD medication in adults ≥50 years, but this review suggests that many patients aged ≥50 years experience beneficial effects of pharmacological treatment. The problem with side effects and somatic complications may rise to a level that makes pharmacotherapy for ADHD difficult after the age of 65 years. Physical assessment prior to initiation of ADHD medication in adults ≥50 years should

  15. Habitat Evaluation Procedures (HEP) Report : Ladd Marsh, 2001 Technical Report.

    Energy Technology Data Exchange (ETDEWEB)

    Oregon Department of Fish and Wildlife

    2001-10-01

    Since the mid-1980s, the Oregon Department of Fish and Wildlife (ODFW) has been participating in the Bonneville Power Administration's (BPA's) efforts to mitigate for the negative impacts to fish and wildlife resulting from the development and operation of the 7 Columbia Basin Federal Hydropower System. BPA's mitigation obligations were formally recognized and mandated by the Northwest Power Act of 1980 and are guided by the Northwest Power Planning Council's (NWPPC's) Columbia Basin Fish and Wildlife Program. BPA funds fish and wildlife projects throughout the Basin to meet the habitat and population restorative goals and objectives outlined in the NWPPC's Fish and Wildlife Program and to fulfill its mitigation responsibilities under the Power Act. Impacts to wildlife resulting from hydrofacility construction/inundation were estimated using Habitat Evaluation Procedures (HEP) in the mid and late 1980s and are documented in BPA' s Wildlife Loss Assessments (Rasmussen and Wright 1990,a,b,c,d) and in the U.S. Army Corps of Engineers Lower Snake River Wildlife Habitat Compensation Evaluation (ACOE 1991). The loss assessments provided estimates of lost habitat quality and quantity for the target species selected to represent the habitat cover types impacted by hydropower construction/inundation. The NWPPC incorporated these losses into their Fish and Wildlife Program, recognizing them as the unannualized losses attributable to the construction/inundation of the federal hydropower system (NWPPC 1995 and 2000, Table 1 1-4). The HEP methodology is used by wildlife managers within the Columbia Basin to determine habitat values, expressed as Habitat Units, gained through BPA-funded mitigation project work. ODFW and the other Oregon wildlife managers (i.e., U.S. Fish and Wildlife Service, Confederated Tribes of the Warms Springs Reservation of Oregon, Burns Paiute Tribe, and Confederated Tribes of the Umatilla Indian Reservation [CTUIR

  16. Peopling of the high Arctic - induced by sea ice?

    Science.gov (United States)

    Funder, Svend

    2010-05-01

    'We travelled in the winter after the return of daylight and did not go into fixed camp until spring, when the ice broke up. There was good hunting on the way, seals, beluga, walrus, bear.' (From Old Merkrusârk's account of his childhood's trek from Baffin Island to Northwest Greenland, told to Knud Rasmussen on Saunders Island in 1904) Five thousand years ago people moving eastwards from Beringia spread over the barrens of the Canadian high Arctic. This was the first of three waves of prehistoric Arctic 'cultures', which eventually reached Greenland. The passage into Greenland has to go through the northernmost and most hostile part of the country with a 5 month Polar night, and to understand this extraordinary example of human behaviour and endurance, it has been customary to invoke a more favourable (warmer) climate. This presentation suggests that land-fast sea ice, i.e. stationary sea ice anchored to the coast, is among the most important environmental factors behind the spread of prehistoric polar cultures. The ice provides the road for travelling and social communion - and access to the most important source of food, the ocean. In the LongTerm Project (2006 and 2007) we attempted to establish a Holocene record for sea ice variations along oceanic coasts in northernmost Greenland. Presently the coasts north of 80° N are beleaguered by year-round sea ice - for ten months this is land-fast ice, and only for a period in the stormy autumn months are the coasts exposed to pack-ice. This presentation Land-fast ice - as opposed to pack-ice - is a product of local temperatures, but its duration over the year, and especially into the daylight season, is also conditioned by other factors, notably wind strength. In the geological record we recognize long lasting land-fast ice by two absences: absence of traces of wave action (no beach formation), which, however, can also be a result of pack-ice along the coast; - and absence of driftwood on the shore (land-fast ice

  17. Linking downhole logging data with geology and drilling /coring operations - Example from Chicxulub Expedition 364.

    Science.gov (United States)

    Lofi, Johanna; Smith, Dave; Delahunty, Chris; Le Ber, Erwan; Mellet, Claire; Brun, Laurent; Henry, Gilles; Paris, Jehanne

    2017-04-01

    faults, as evidenced from borehole wall images. Both form conduits probably open at a large scale as suggested by associated anomalies in the borehole fluid temperature profiles. When coring the basement, pieces of metal trapped outside the drill bit apparently led to an increase of the borehole tilt as well as to an enlargement of the hole, although this later remained sub-circular. In the post impact carbonates, 6-7 m long apparent cyclic oscillations in the magnetic field coupled to a spiral shape trajectory of the same wavelength suggest drilling induced artifacts and formation re-magnetization. Acknowledgements: Expedition 364 was funded by IODP with co-funding from ICDP and implemented by ECORD, with contributions and logistical support from the Yucatán state government and Universidad Nacional Autónoma de México. Drilling Services were provided by DOSECC Exploration Services. The downhole logging program was coordinated by EPC, as part of ESO. Expedition 364 Scientists: S. Gulick, J.V. Morgan, E. Chenot, G. Christeson, P. Claeys, C. Cockell, M.J. L. Coolen, L. Ferrière, C. Gebhardt, K. Goto, H. Jones, D.A. Kring, J. Lofi, X. Long, C. Lowery, C. Mellett, R. Ocampo-Torres, L. Perez-Cruz, A. Pickersgill, M. Poelchau, A. Rae, C. Rasmussen, M. Rebolledo-Vieyra, U. Riller, H. Sato, J. Smit, S. Tikoo, N. Tomioka, M. Whalen, A. Wittmann, J. Urrutia-Fucugauchi, K.E. Yamaguchi, W. Zylberman.

  18. Investigating the Microscopic Location of Trace Elements in High-Alpine Glacier Ice

    Science.gov (United States)

    Avak, Sven Erik; Birrer, Mario; Laurent, Oscar; Guillong, Marcel; Wälle, Markus; Jenk, Theo Manuel; Bartels-Rausch, Thorsten; Schwikowski, Margit; Eichler, Anja

    2017-04-01

    proxies in glaciers partially affected by melting. References Della Lunga, D., Müller, W., Rasmussen, S. O. & Svensson, A. 2014: Location of cation impurities in NGRIP deep ice revealed by cryo-cell UV-laser-ablation ICPMS, Journal of Glaciology, 60, 970-988. Eichler, A., Schwikowski, M., Gäggeler, H. W. 2001: Meltwater-induced relocation of chemical species in Alpine firn, Tellus B, 53, 192-203. Reinhardt, H., Kriews, M., Miller, H., Schrems, O., Lüdke, C., Hoffmann, E. & Skole, J. 2001: Laser ablation inductively coupled plasma mass spectrometry: a new tool for trace element analysis in ice cores, Fresenius' Journal of Analytical Chemistry, 370, 629-636. Schwikowski, M., Barbante, C., Doering, T., Gäggeler, H. W., Boutron, C., Schotterer, U., Tobler, L., van de Velde, K., Ferrari, C., Cozzi, G., Rosman, K., Cescon, P. 2004: Post-17th-Century Changes of European Lead Emissions Recorded in High-Altitude Alpine Snow and Ice, Environmental Science & Technology, 38, 957-964. Sneed, S. B., Mayewski, P. A., Sayre, W. G., Handley, M. J., Kurbatov, A. V., Taylor, K. C., Bohleber, P., Wagenbach, D., Erhardt, T. & Spaulding, N. E. 2015: New LA-ICP-MS cryocell and calibration technique for sub-millimeter analysis of ice cores, Journal of Glaciology, 61, 233-242.

  19. Comparison of global gene expression profiles of microdissected human foetal Leydig cells with their normal and hyperplastic adult equivalents.

    Science.gov (United States)

    Lottrup, Grete; Belling, Kirstine; Leffers, Henrik; Nielsen, John E; Dalgaard, Marlene D; Juul, Anders; Skakkebæk, Niels E; Brunak, Søren; Rajpert-De Meyts, Ewa

    2017-05-01

    . The study revealed several genes not known previously to be expressed in LCs during early development, including sulfotransferase family 2A member 1 (SULT2A1), WNT1-inducible signalling pathway protein 2 (WISP2), hydroxyprostaglandin dehydrogenase (HPGD) and insulin-like growth factor 2 mRNA binding protein 1 (IGF2BP1), whose expression changes were validated at the protein level. The transcriptomic data are deposited in ArrayExpress (accession code E-MTAB-5453). The small number of biological replicates and the necessity of RNA amplification due to the scarcity of human tissues, especially foetal specimens, are the main limitations of the study. Heterogeneous subpopulations of LCs within micronodules were not discriminated during microdissection and might have affected the expression profiling. The study was constrained by the lack of availability of truly normal controls. Testis samples used as 'controls' displayed complete spermatogenesis and were from patients with germ cell neoplasia but with undetectable hCG and normal hormone levels. The changes in LC morphology and function observed in patients with reproductive disorders possibly reflect subtle changes in the expression of many genes rather than regulatory changes of single genes or pathways. The study provides new insights into the development and maturation of human LCs by the identification of a number of potential functional markers for FLC and ALC. The study was supported by research grants from the Danish Cancer Society, the Capital Region's Research Fund for Health Research, Rigshospitalet's research funds, the Villum Kann Rasmussen Foundation, the Danish Innovation Fund, ReproUnion, Kirsten and Freddy Johansen's foundation and the Novo Nordisk Foundation. None of the funding agencies had any influence on the study. The authors declare no conflicts of interest.

  20. Probe microphone measurements: 20 years of progress.

    Science.gov (United States)

    Mueller, H G

    2001-06-01

    Probe-microphone testing was conducted in the laboratory as early as the 1940s (e.g., the classic work of Wiener and Ross, reported in 1946), however, it was not until the late 1970s that a "dispenser friendly" system was available for testing hearing aids in the real ear. In this case, the term "dispenser friendly," is used somewhat loosely. The 1970s equipment that I'm referring to was first described in a paper that was presented by Earl Harford, Ph.D. in September of 1979 at the International Ear Clinics' Symposium in Minneapolis. At this meeting, Earl reported on his clinical experiences of testing hearing aids in the real ear using a miniature (by 1979 standards) Knowles microphone. The microphone was coupled to an interfacing impedance matching system (developed by David Preves, Ph.D., who at the time worked at Starkey Laboratories) which could be used with existing hearing aid analyzer systems (see Harford, 1980 for review of this early work). Unlike today's probe tube microphone systems, this early method of clinical real-ear measurement involved putting the entire microphone (about 4mm by 5mm by 2mm) in the ear canal down by the eardrum of the patient. If you think cerumen is a problem with probe-mic measurements today, you should have seen the condition of this microphone after a day's work! While this early instrumentation was a bit cumbersome, we quickly learned the advantages that probe-microphone measures provided in the fitting of hearing aids. We frequently ran into calibration and equalization problems, not to mention a yelp or two from the patient, but the resulting information was worth the trouble. Help soon arrived. In the early 1980s, the first computerized probe-tube microphone system, the Rastronics CCI-10 (developed in Denmark by Steen Rasmussen), entered the U.S. market (Nielsen and Rasmussen, 1984). This system had a silicone tube attached to the microphone (the transmission of sound through this tube was part of the calibration process

  1. Coeval dust accumulation minima in Greenland and East Central Europe over 31-23 ka

    Science.gov (United States)

    Újvári, Gábor; Stevens, Thomas; Varga, György; Kovács, János; Molnár, Mihály

    2016-04-01

    with the bulk loess median grain size (D50bulk) that is considered an integrated proxy of wind strength, dust source distance, aridity and vegetation cover. While an increase of dust flux and D50bulk with time is apparent, such a trend cannot be seen in the quartz grain size measures (D50quartz). This observation may imply that wind speeds were relatively constant in the studied time interval, while the turbulence of the flow may have been extremely varying (i.e. strong/rapid changes in the frequency/magnitude of dust storm events). A striking feature of the MAR record is that accumulation minima in the Dunaszekcsö record are synchronous with the Greenland Interstadials (GI-5.1 to GI-3). Subsequent Ca2+ minima in the NGRIP record at 26.22 and 25.02 ka (b2k) are also coeval with the MAR minima in the studied loess sequence. At the same time, these patterns are barely visible in the bulk and quartz grain size records. We speculate that the synchronous changes in the NGRIP Ca2+ and the Dunaszekcsö MAR records are results of millennial scale variations in the activity of Northern Hemisphere dust emitting regions shown in two archives from different environments. The very similar timing of MAR minima (and also some of the maxima) suggest a rapid aeolian system response in East Central Europe to abrupt climatic changes in the North Atlantic. Although such a synchronicity does not prove a Central European dust source to Greenland, it is consistent with this possibility. This study was supported by the OTKA PD-108639 grant and the Bolyai János Research Fellowship (both to GÚ). [1] Dansgaard, W., et al. (1993). Evidence for general instability of past climate from a 250-kyr ice-core record. Nature 364, 218-220. [2] Johnsen, S.J., et al. (1992). Irregular glacial interstadials recorded in a new Greenland ice core. Nature 359, 311-313. [3] Rasmussen, S.O., et al. (2014). A stratigraphic framework for abrupt climatic changes during the Last Glacial period based on three

  2. Uranium isotopic compositions of the crust and ocean: Age corrections, U budget and global extent of modern anoxia

    Science.gov (United States)

    Tissot, François L. H.; Dauphas, Nicolas

    2015-10-01

    in terrestrial surface environments: U4+ is insoluble in seawater while U6+ is soluble (Langmuir, 1978). The contrasting behaviors of the two oxidation states of uranium explains why the disappearance of detrital uraninite after the Archean marks the rise of oxygen in Earth's atmosphere/hydrosphere (Ramdohr, 1958; Rasmussen and Buick, 1999; Frimmel, 2005). More recently, significant effort has focused on using U isotopes to constrain the past extents of anoxic/euxinic vs. oxic or suboxic sediments in modern and ancient oceans (Montoya-Pino et al., 2010; Brennecka et al., 2011a; Asael et al., 2013; Kendall et al., 2013, 2015; Andersen et al., 2014; Dahl et al., 2014; Goto et al., 2014; Noordmann et al., 2015). A virtue of this system is that it can potentially reflect the global redox state of Earth's oceans. At the same time, several difficulties have been encountered in applying U isotopes as paleo-redox indicators. For example, detrital contributions can blur the authigenic signal and have to be corrected for (Asael et al., 2013; Andersen et al., 2014; Noordmann et al., 2015), uranium isotopes can be affected by diagenesis and exchange with porewater (Romaniello et al., 2013; Andersen et al., 2014), and the exact isotopic fractionation factors relevant to various conditions of deposition are uncertain. While significant progress has already been made to address these difficulties (Asael et al., 2013; Romaniello et al., 2013; Andersen et al., 2014; Noordmann et al., 2015), this system and others are missing some of the groundwork studies on modern environments that are needed to gain trust in their applications to ancient sediments.In the modern ocean, water-soluble uranium behaves conservatively (i.e., U concentration correlates linearly to water salinity, Ku et al., 1977; Owens et al., 2011) and has a long residence time of ∼400 kyr (Ku et al., 1977). The ocean is therefore a large repository of uranium, exceeding the total inventory of land-based deposits (Lu

  3. Fission and Properties of Neutron-Rich Nuclei

    Science.gov (United States)

    Hamilton, Joseph H.; Ramayya, A. V.; Carter, H. K.

    2008-08-01

    near A= 120 / M. A. Stoyer and W. B. Walters -- Nuclear structure IV. First observation of new neutron-rich magnesium, aluminum and silicon isotopes / A. Stolz ... [et al.]. Spectroscopy of [symbol]Na revolution of shell structure with isospin / V. Tripathi ... [et al.]. Rearrangement of proton single particle orbitals in neutron-rich potassium isotopes - spectroscopy of [symbol]K / W. Królas ... [et al.]. Laser spectroscopy and the nature of the shape transition at N [symbol] 60 / B. Cheal ... [et al.]. Study of nuclei near stability as fission fragments following heavy-ion reactions / N. Fotiadis. [symbol]C and [symbol]N: lifetime measurements of their first-excited states / M. Wiedeking ... [et al.] -- Nuclear astrophysics. Isomer spectroscopy near [symbol]Sn - first observation of excited states in [symbol]Cd / M. Pfitzner ... [et al.]. Nuclear masses and what they imply for the structures of neutron rich nuclei / A. Awahamian and A. Teymurazyan. Multiple nucleosynthesis processes in the early universe / F. Montes. Single-neutron structure of neutron-rich nuclei near N = 50 and N = 82 / J. A. Cizewski ... [et al.]. [symbol]Cadmium: ugly duckling or young swan / W. B. Walters ... [et al.] -- Nuclear structure V. Evidence for chiral doublet bands in [symbol]Ru / Y. X. Luo ... [et al.]. Unusual octupole shape deformation terms and K-mixing / J. O. Rasmussen ... [et al.]. Spin assignments, mixing ratios, and g-factors in neutron rich [symbol]Cf fission products / C. Goodin ... [et al.]. Level structures and double [symbol]-bands in [symbol]Mo, [symbol]Mo and [symbol]Ru / S. J. Zhu ... [et al.] -- Nuclear theory. Microscopic dynamics of shape coexistence phenomena around [symbol]Se and [symbol]Kr / N. Hinohara ... [et al.]. Nuclear structure, double beta decay and test of physics beyond the standard model / A. Faessler. Collective modes in elastic nuclear matter / Ş. Mişicu and S. Bastrukov. From N = Z to neutron rich: magnetic moments of Cu isotopes at and above the

  4. EDITORIAL: Focus on Cold and Ultracold Molecules FOCUS ON COLD AND ULTRACOLD MOLECULES

    Science.gov (United States)

    Carr, Lincoln D.; Ye, Jun

    2009-05-01

    öhlich, A Griesmaier, T Pfau, H Saito, Y Kawaguchi and M Ueda High-energy-resolution molecular beams for cold collision studies L P Parazzoli, N Fitch, D S Lobser and H J Lewandowski Collisional effects in the formation of cold guided beams of polar molecules M Motsch, C Sommer, M Zeppenfeld, L D van Buuren, P W H Pinkse and G Rempe Towards sympathetic cooling of large molecules: cold collisions between benzene and rare gas atoms P Barletta, J Tennyson and P F Barker Efficient formation of ground-state ultracold molecules via STIRAP from the continuum at a Feshbach resonance Elena Kuznetsova, Marko Gacesa, Philippe Pellegrini, Susanne F Yelin and Robin Côté Emergent timescales in entangled quantum dynamics of ultracold molecules in optical lattices M L Wall and L D Carr Rotational state resolved photodissociation spectroscopy of translationally and vibrationally cold MgH+ ions: toward rotational cooling of molecular ions K Højbjerre, A K Hansen, P S Skyt, P F Staanum and M Drewsen Collective transverse cavity cooling of a dense molecular beam Thomas Salzburger and Helmut Ritsch A Stark decelerator on a chip Samuel A Meek, Horst Conrad and Gerard Meijer Deceleration of molecules by dipole force potential: a numerical simulation Susumu Kuma and Takamasa Momose Ultracold molecules: vehicles to scalable quantum information processing Kathy-Anne Brickman Soderberg, Nathan Gemelke and Cheng Chin Magnetic field modification of ultracold molecule-molecule collisions T V Tscherbul, Yu V Suleimanov, V Aquilanti and R V Krems Spectroscopy of 39K85Rb triplet excited states using ultracold a 3Σ+ state molecules formed by photoassociation J T Kim, D Wang, E E Eyler, P L Gould and W C Stwalley Pumping vortex into a Bose-Einstein condensate of heteronuclear molecules Z F Xu, R Q Wang and L You Intense atomic and molecular beams via neon buffer-gas cooling David Patterson, Julia Rasmussen and John M Doyle Dynamical properties of dipolar Fermi gases T Sogo, L He, T Miyakawa, S Yi, H Lu

  5. Selected Abstracts of the 1st Congress of joint European Neonatal Societies (jENS 2015; Budapest (Hungary; September 16-20, 2015; Session “Circulation, O2 Transport and Haematology”

    Directory of Open Access Journals (Sweden)

    Various Authors

    2015-09-01

    SEVERE NEONATAL HYPOXIC-ISCHEMIC ENCEPHALOPATHY (HIE DURING WHOLE BODY HYPOTHERMIA (WBH • P. López-Ortego, J. Riera, M.C. Bravo, L. Sanchez, R. Madero, E. Valverde, F. Cabañas, A. PellicerABS 40. PACAP CAN INFLUENCE THE VASCULAR CHANGES IN THE ANIMAL MODEL OF RETINOPATHY OF PREMATURITY • T. Kvarik, B. Mammel, D. Werling, A. Vaczy, D. Reglodi, T. Ertl, J. Gyarmati, T. AtlaszABS 41. DOPAMINE INFUSION IMPROVES CEREBRAL AUTOREGUALTION IN NEWBORN PIGLETS • V.R. Eriksen, M. Rasmussen, G.H. Hahn, G. GreisenABS 42. OPTIMAL MEAN ARTERIAL BLOOD PRESSURE IN PRETERM INFANTS WITH LESS THAN 24 HOURS OF AGE • C.S. da Costa, M Czosnyka, P. Smielewski, G. Stevenson, C. Kemp, T. AustinABS 43. THE IMPACT OF PREMATURE LUNG DISEASE ON THE MATURATION OF CARDIAC PERFORMANCE IN THE FIRST YEAR OF LIFE: DISCERNING EARLY PREDICTIVE MARKERS OF CHRONIC LUNG DISEASE • P. Levy, A. Sanchez, T. Sekarski, M. Holland, A. Hamvas, G. SinghABS 44. THE MYOCARDIAL ARCHITECTURE CHANGES DUE TO PERSISTENT PULMONARY HYPERTENSION OF THE NEWBORN IN AN OVINE ANIMAL MODEL • P. Agger, S. Lakshminrusimha, C. Laustsen, S. Gugino, J.R. Frandsen, M. Smerup, R.H. Anderson, V. Hjortdal, R.H. SteinhornABS 45. EFFECT OF WITHHOLDING FEEDS ON TRANSFUSION-RELATED ACUTE GUT INJURY IN PRETERM INFANTS – A RANDOMISED CONTROLLED TRIAL • S. Sahin, G.K. Kutman, O. Bozkurt, F.Y. Atay, F.E. Canpolat, N. Uras, S.S. Oğuz

  6. PREFACE: The IARU International Scientific Congress on Climate Change: Global Risks, Challenges and Decisions (10-12 March, Copenhagen, Denmark)

    Science.gov (United States)

    2009-01-01

    In an attempt to make the main results from the Congress on Climate Change: Global Risk, Challenges and Decisions available to the public as early as possible, the steering committee decided to publish all talks and posters presented at the Congress in this unique collection of abstracts, in time for the conference Further to the abstract collection the Congress will publish two more products in the near future as described in the following; a synthesis report with the main conclusions, and a book aimed at an academic audience 1 Two Products from the Congress Two products are being produced based on the presentations and discussions at the Congress The first product will be a synthesis report of the main conclusions from the Congress The synthesis report will be ready in June 2009 The synthesis has the purpose of explaining the current state of understanding man-made climate change and what we can do about it to the non-scientist, ie politicians, media and interested citizens The synthesis will build on the messages presented to the Danish Prime Minister, Mr Anders Fogh Rasmussen, host of the COP15, at the closing session of the Congress These six messages were drafted by the Writing Team (see below) based on input from the session chairs and a reading of the 1600+ abstracts submitted to the Congress The second product is a book aimed at an academic audience The book will include more detailed scientific results from all of the sessions and will be published by Cambridge University Press in 2010 It will be an extension and elaboration of the synthesis report Who's writing the Synthesis Report and the Book? A Writing Team consisting of 12 internationally respected scientists from all continents is responsible for developing both products When the synthesis report has been drafted by the Writing Team, it will be discussed in the Scientific Steering Committee of the Congress and reviewed by the Earth System Science Partnership (ESSP) and a group of experts identified

  7. Dabartinės lietuvių kalbos priesagos -ėti denominatyviniai statyvai

    Directory of Open Access Journals (Sweden)

    Jurgis Pakerys

    2011-12-01

    statives in -ėti are an unproductive derivational category in Modern Lithuanian. It is still possible to identify some isolated groups characterized by presents in -ė-ja, -i, -i-si or -a. Predominant inchoative semantics of Lithuanian denominatives in -ėti is probably to be considered an innovation. As inchoatives in -ėti, -ėja started to gain ground, at least some statives adopted i-stem presents (a typical feature of deverbative statives. If Indo-European formations in *-eh1- primarily had presents in *-eh1-i̯e/o- (as argued by Jasanoff 200212003, 147; cf. reconstructions of athematic inflection *-eh1-ti by Watkins 1971, 83; Jasanof f 1978, 124; Ruijgh 2004, 56 and zero-grade suffix in *-e-h1-ie/o- suggested by Rasmussen 1993, 481 and Hardarson 1998, 337, the more archaic morphology was taken over by the dominating inchoative type in Lithuanian, while the possibly archaic stative type lost the morphological uniformity of the present stem and drifted towards deverbative i-presents. Many of the latter ones became derivationally obscure as verbs in -ėti, -i can be considered as bases for the productive formation of deverbative u-stem adjectives in Modern Lithuanian. The space left by (formerly productive? statives in -ėti was taken over by new denominative suffixes, cf.: gudr-áuti ‘to act using tricks’ : gudrùs ‘clever, cunning’, draug-áuti ‘to be friends’ : draũgas ‘friend’, balt-úoti ‘to be white’ : báltas ‘white’, šnip-inė́ti ‘to spy’: šnìpas ‘spy’.

  8. Free and Open Source Software underpinning the European Forest Data Centre

    Science.gov (United States)

    Rodriguez Aseretto, Dario; Di Leo, Margherita; de Rigo, Daniele; Corti, Paolo; McInerney, Daniel; Camia, Andrea; San-Miguel-Ayanz, Jesús

    2013-04-01

    ), 104-103. http://dx.doi.org/10.1109/MC.2007.292 Cai, Y., Judd, K. L., Lontzek, T. S., May 2012. Open science is necessary. Nature Climate Change 2 (5), 299. http://dx.doi.org/10.1038/nclimate1509 Sonnenburg, S., Braun, M. L., Ong, C. S., Bengio, S., Bottou, L., Holmes, G., LeCun, Y., Müller, K. R., Pereira, F., Rasmussen, C. E., Rätsch, G., Schölkopf, B., Smola, A., Vincent, P., Weston, J., Williamson, R., Dec. 2007. The need for open source software in machine learning. J. Mach. Learn. Res. 8, 2443-2466. http://jmlr.csail.mit.edu/papers/v8/sonnenburg07a.html de Vos, M. G., Janssen, S. J. C., van Bussel, L. G. J., Kromdijk, J., van Vliet, J., Top, J. L., Dec. 2011. Are environmental models transparent and reproducible enough? In: Chan, F., Marinova, D., Anderssen, R. S. (Eds.), MODSIM2011, 19th International Congress on Modelling and Simulation. Modelling and Simulation Society of Australia and New Zealand, pp. 2954-2961. http://www.mssanz.org.au/modsim2011/G7/devos.pdf Peng, R. D., 2011. Reproducible research in computational science. Science 334 (6060), 1226-1227. http://dx.doi.org/10.1126/science.1213847 European Commission, 2011. Strategy for internal use of OSS at the EC. European Commission, Directorate-General for Informatics (DIGIT). http://ec.europa.eu/dgs/informatics/oss_tech/index_en.htm (archived at: http://www.webcitation.org/6DXuBeTAU ) European Commission, 2006. European Union forest action plan. No. COM(2006) 302 final. Communication from the Commission. http://eur-lex.europa.eu/LexUriServ/LexUriServ.do?uri=COM:2006:0302:FIN:EN:HTML Ticheler, J., Hielkema, J. U., 2007. GeoNetwork opensource. OSGeo Journal 2, 1-5. http://journal.osgeo.org/index.php/journal/article/viewFile/86/69 European Parliament, 2007. Directive 2007/2/EC of the European Parliament and of the Council of 14 march 2007 establishing an infrastructure for spatial information in the european community (INSPIRE). Official Journal of the European Union 50 (L 108), 1-14. http://eur-lex

  9. Selected Abstracts of the 1st Congress of joint European Neonatal Societies (jENS 2015; Budapest (Hungary; September 16-20, 2015; Session “Brain & Development”

    Directory of Open Access Journals (Sweden)

    Various Authors

    2015-09-01

    . Agyemang, S. Vallius, D. Ley, M. GramABS 70. FINGOLIMOD REDUCES NEONATAL WHITE MATTER DAMAGE AND LONG-TERM COGNITIVE DEFICITS • I. Bendix, M. Serdar, K. Kempe, J. Herz, K. Lumpe, B.S. Reinboth, S.V. Sizonenko, X. Hou, R. Herrmann, M. Hadamitzky, R. Heumann, M. Sifringer, Y.v.d. Looji, U. Felderhoff-MüserABS 71. NEURODEVELOPMENTAL OUTCOME AFTER EARLY HIGH DOSE RECOMBINANT HUMAN ERYTHROPOIETIN IN VERY PRETERM INFANTS: RESULTS OF A RANDOMIZED PLACEBO-CONTROLLED, DOUBLE-BLIND TRIAL • G. Natalucci, B. Latal, B. Koller, C. Rüegger, B. Sick, L. Held, H.U. Bucher, J.C. Fauchère; on behalf of the ‘The Swiss EPO Neuroprotection Trial Group’ABS 72. THE HEME AND RADICAL SCAVENGER α1-MICROGLOBULIN (A1M CONFERS PROTECTION OF THE PERIVENTRICULAR WHITE MATTER FOLLOWING PRETERM INTRAVENTRICULAR HEMORRHAGE • S. Rutardottir, S. Sveinsdottir, S.R. Hansson, B. Åkerström, D. Ley, M. GramABS 73. VALIDATION OF CEREBRAL NIRS OXIMETRY IN NEWBORN PIGLETS • M. Rasmussen, V. Eriksen, S. Hyttel-Sorensen, G. GreisenABS 74. BRAIN INJURY IN THE INTERNATIONAL MULTICENTRE RANDOMISED SafeBoosC PHASE II FEASIBILITY TRIAL: CRANIAL ULTRASOUND AND MAGNETIC RESONANCE IMAGING ASSESSMENTS • A.M. Plomgaard, C. Hagmann, T. Alderliesten, T. Austin, F. van Bel, O. Claris, E. Dempsey, A. Franz, M. Fumagalli, C. Gluud, G. Greisen, S. Hyttel-Soerensen, P. Lemmers, A. Pellicer, G. Pichler, M. BendersABS 75. DELAYED CORD CLAMPING AT BIRTH IMPROVES MOTOR SCORES AT 18 TO 22 MONTHS CORRECTED AGE: A RANDOMIZED CONTROLLED TRIAL • J. Mercer, D. Erickson-Owens, B. Vohr, R. Tucker, W. Oh, J. PadburyABS 76. VOICE OUTCOMES FOLLOWING VERY PRETERM BIRTH • S. Meldrum, K. Simmer, S. Vijayasekaran, N. FrenchABS 77. TIMING OF AMPLITUDE-INTEGRATED ELECTROENCEPHALOGRAPHY RECORDING FOR PREDICTION OF OUTCOME IN PREMATURE INFANTS • E. Ralser, V. Neubauer, U. Pupp-Peglow, U. Kiechl-Kohlendorfer, E. GriesmaierABS 78. BAYLEY SCALES OF INFANT AND TODDLER DEVELOPMENT (EDITION 3 IN A LOW RISK HEALTHY POPULATION • C