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Sample records for brookhaven practical considerations

  1. BROOKHAVEN

    International Nuclear Information System (INIS)

    Neutrino physics has been an integral part of the Brookhaven research programme for much of the Laboratory's 46-year history. Milestones have been the determination of the helicity of neutrinos (1958), the establishment of the existence of two kinds of neutrinos (1962) for which Leon Lederman, Mel Schwartz and Jack Steinberger were awarded the 1988 Nobel Physics Prize, the discovery of charmed baryons in the 7' Bubble Chamber in 1975, and the ongoing measurements by Ray Davis and collaborators of solar neutrinos, first reported in 1968. There have also been significant contributions to the understanding of neutral currents in exclusive hadron and electron channels. In addition some of the earliest, and to date best, accelerator limits on electron muon neutrino oscillations are from Brookhaven experiments. The Laboratory is also the 'B' in the IMB underground experiment, built to search for proton decay and which caught neutrinos from the SN 1987a supernova. At present Brookhaven is heavily involved in the Gallex project in the Gran Sasso and recently a new collaboration has received scientific approval for a long baseline experiment to search for muon neutrino oscillations via muon neutrino disappearance

  2. Protocols for BNCT of glioblastoma multiforme at Brookhaven: Practical considerations

    Energy Technology Data Exchange (ETDEWEB)

    Chanana, A.D.; Coderre, J.A.; Joel, D.D.; Slatkin, D.N.

    1996-12-31

    In this report we discuss some issues considered in selecting initial protocols for boron neutron capture therapy (BNCT) of human glioblastoma multiforme. First the tolerance of normal tissues, especially the brain, to the radiation field. Radiation doses limits were based on results with human and animal exposures. Estimates of tumor control doses were based on the results of single-fraction photon therapy and single fraction BNCT both in humans and experimental animals. Of the two boron compounds (BSH and BPA), BPA was chosen since a FDA-sanctioned protocol for distribution in humans was in effect at the time the first BNCT protocols were written and therapy studies in experimental animals had shown it to be more effective than BSH.

  3. The Phase I/II BNCT Trials at the Brookhaven medical research reactor: Critical considerations

    International Nuclear Information System (INIS)

    A phase I/II clinical trial of boronophenylalanine-fructose (BPA-F) mediated boron neutron capture therapy (BNCT) for Glioblastoma Multiforme (GBM) was initiated at Brookhaven National Laboratory (BNL) in 1994. Many critical issues were considered during the design of the first of many sequential dose escalation protocols. These critical issues included patient selection criteria, boron delivery agent, dose limits to the normal brain, dose escalation schemes for both neutron exposure and boron dose, and fractionation. As the clinical protocols progressed and evaluation of the tolerance of the central nervous system (CNS) to BPA-mediated BNCT at the BMRR continued new specifications were adopted. Clinical data reflecting the progression of the protocols will be presented to illustrate the steps taken and the reasons behind their adoption. (author)

  4. Brookhaven highlights

    International Nuclear Information System (INIS)

    This report highlights the research activities of Brookhaven National Laboratory during the period dating from October 1, 1992 through September 30, 1993. There are contributions to the report from different programs and departments within the laboratory. These include technology transfer, RHIC, Alternating Gradient Synchrotron, physics, biology, national synchrotron light source, applied science, medical science, advanced technology, chemistry, reactor physics, safety and environmental protection, instrumentation, and computing and communications

  5. Brookhaven highlights

    International Nuclear Information System (INIS)

    This publication provides a broad overview of the research programs and efforts being conducted, built, designed, and planned at Brookhaven National Laboratory. This work covers a broad range of scientific disciplines. Major facilities include the Alternating Gradient Synchrotron (AGS), with its newly completed booster, the National Synchrotron Light Source (NSLS), the High Flux Beam Reactor (HFBR), and the RHIC, which is under construction. Departments within the laboratory include the AGS department, accelerator development, physics, chemistry, biology, NSLS, medical, nuclear energy, and interdepartmental research efforts. Research ranges from the pure sciences, in nuclear physics and high energy physics as one example, to environmental work in applied science to study climatic effects, from efforts in biology which are a component of the human genome project to the study, production, and characterization of new materials. The paper provides an overview of the laboratory operations during 1992, including staffing, research, honors, funding, and general laboratory plans for the future

  6. Brookhaven highlights

    Energy Technology Data Exchange (ETDEWEB)

    Rowe, M.S.; Cohen, A.; Greenberg, D.; Seubert, L. (eds.)

    1992-01-01

    This publication provides a broad overview of the research programs and efforts being conducted, built, designed, and planned at Brookhaven National Laboratory. This work covers a broad range of scientific disciplines. Major facilities include the Alternating Gradient Synchrotron (AGS), with its newly completed booster, the National Synchrotron Light Source (NSLS), the High Flux Beam Reactor (HFBR), and the RHIC, which is under construction. Departments within the laboratory include the AGS department, accelerator development, physics, chemistry, biology, NSLS, medical, nuclear energy, and interdepartmental research efforts. Research ranges from the pure sciences, in nuclear physics and high energy physics as one example, to environmental work in applied science to study climatic effects, from efforts in biology which are a component of the human genome project to the study, production, and characterization of new materials. The paper provides an overview of the laboratory operations during 1992, including staffing, research, honors, funding, and general laboratory plans for the future.

  7. Legal Considerations of Psychiatric Nursing Practice.

    Science.gov (United States)

    Barloon, Linda Funk; Hilliard, Wanda

    2016-06-01

    There are major legal issues that affect psychiatric nursing and guidelines for practicing in a legal and responsible manner. Advances in understanding of psychiatric conditions and developments in how nurses care for psychiatric patients result in changes in regulations, case law, and policies that govern nursing practice. Professional development, keeping abreast of current research and literature regarding clinical practice and trends, and involvement in professional organizations are some of the ways that psychiatric nurses can meet the challenges of their profession. PMID:27229273

  8. Practical considerations in voltage stability assessment

    Energy Technology Data Exchange (ETDEWEB)

    Kundur, P.; Gao, B. [Powertech Labs. Inc., Surrey, BC (Canada)

    1994-12-31

    This paper deals with some of the most important practical issues related to voltage stability assessment of large practical systems. A brief discussion of the practical aspects of voltage stability problem and prevention of voltage instability is given first, followed by descriptions of different analytical techniques and tools for voltage stability analysis. Presentations of analytical tools is focused on the VSTAB program which incorporates the modal analysis, continuation power flow, and shortest distance to instability techniques, Finally, an example case study of a practical large system is presented. The case study illustrates how modal analysis is used to determine the most effective load shedding scheme for preventing voltage instability. (author) 15 refs., 2 figs., 2 tabs.

  9. Practical considerations for polymer photonic devices

    Science.gov (United States)

    Ticknor, Anthony J.; Lipscomb, George F.; Lytel, Richard S.

    1994-09-01

    Electro-optic (EO) poled polymer materials exhibit low dispersion and low dielectric constants. EO polymer materials have been modulated flat to 40 GHz and exhibit few fundamental limits for ultrafast modulation and switching. Channel waveguides and integrated optic circuits can be defined by the poling process itself, by photochemistry of the EO polymer, or by a variety of well understood micro-machining techniques. EO polymer materials have been used to fabricate high-speed Mach-Zehnder modulators, directional couplers, Fabry-Perot etalons, and even multi-tap devices. Practical issues remain to be solved before polymer photonic technology may be exploited in systems such as datacom and telecom. These include reliable, low cost fiber-attach and packaging, support circuitry and interfaces, and the scale-up to high volume production. This talk reviews requirements for practical exploitation and displays recent progress toward achieving reliable products.

  10. Brookhaven highlights - Brookhaven National Laboratory 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-09-01

    This report highlights research conducted at Brookhaven National Laboratory in the following areas: alternating gradient synchrotron; physics; biology; national synchrotron light source; department of applied science; medical; chemistry; department of advanced technology; reactor; safety and environmental protection; instrumentation; and computing and communications.

  11. Altered Practice Altered Stories Altered Lives: Three Considerations for Translating Organizational Communication Scholarship into Practice.

    Science.gov (United States)

    Tracy, Sarah J.

    2002-01-01

    Offers three "unabashedly normative" considerations for translating organizational communication scholarship to practice: identifying a problem, incorporating participant voices, and presenting research to practitioners. Suggests that by engaging in these practices scholars can create alternative organizational stories and in doing so create space…

  12. Brookhaven segment interconnect

    International Nuclear Information System (INIS)

    We have performed a high energy physics experiment using a multisegment Brookhaven FASTBUS system. The system was composed of three crate segments and two cable segments. We discuss the segment interconnect module which permits communication between the various segments

  13. Massachusetts Institute of Technology School of Chemical Engineering Practice, Brookhaven station: Summary of projects, 1983-1986

    Energy Technology Data Exchange (ETDEWEB)

    1987-11-01

    The MIT Graduate School of Chemical Engineering Practice stresses engineering problem solving. The Practice School program, as it is commonly called, develops in a unique and particularly effective way the student's ability to apply fundamentals to problems in the chemical industry and thus accelerates one's professional development. The themes of atomization, emthanol production and utilization, hydrogen production and compression, localized electrochemical corrosion and biochemical engineering reflect some of the major programs at the Laboratory. The titles of all the projects are listed in chronological order in the index at the end of this document. Brief summaries are presented for each project with related projects grouped together.

  14. Massachusetts Institute of Technology School of Chemical Engineering Practice, Brookhaven station: Summary of projects, 1983-1986

    International Nuclear Information System (INIS)

    The MIT Graduate School of Chemical Engineering Practice stresses engineering problem solving. The Practice School program, as it is commonly called, develops in a unique and particularly effective way the student's ability to apply fundamentals to problems in the chemical industry and thus accelerates one's professional development. The themes of atomization, emthanol production and utilization, hydrogen production and compression, localized electrochemical corrosion and biochemical engineering reflect some of the major programs at the Laboratory. The titles of all the projects are listed in chronological order in the index at the end of this document. Brief summaries are presented for each project with related projects grouped together

  15. Practical clinical considerations of luting cements: A review.

    Science.gov (United States)

    Lad, Pritam P; Kamath, Maya; Tarale, Kavita; Kusugal, Preethi B

    2014-02-01

    The longevity of fixed partial denture depends on the type of luting cement used with tooth preparation. The clinician's understating of various cements, their advantages and disadvantages is of utmost importance. In recent years, many luting agents cements have been introduced claiming clinically better performance than existing materials due to improved characteristics. Both conventional and contemporary dental luting cements are discussed here. The various agents discussed are: Zinc phosphate, Zinc polycarboxylate, Zinc oxide-eugenol, Glass-ionomer, Resin modified GIC, Compomers and Resin cement. The purpose of this article is to provide a discussion that provides a clinical perspective of luting cements currently available to help the general practitioner make smarter and appropriate choices. How to cite the article: Lad PP, Kamath M, Tarale K, Kusugal PB. Practical clinical considerations of luting cements: A review. J Int Oral Health 2014;6(1):116-20. PMID:24653615

  16. BROOKHAVEN: High energy gold

    International Nuclear Information System (INIS)

    On April 24, Brookhaven's Alternating Gradient Synchrotron (AGS) started to deliver gold ions at 11.4 GeV per nucleon (2,000 GeV per ion) to experimenters who were delighted not only to receive the world's highest energy gold beam but also to receive it on schedule

  17. Practical considerations for bicarbonate loading and sports performance.

    Science.gov (United States)

    Burke, Louise M

    2013-01-01

    Consumption of sodium bicarbonate (300 mg/kg 1-2 h before exercise) can temporarily increase blood bicarbonate concentrations, enhancing extracellular buffering of hydrogen ions which accumulate and efflux from the working muscle. Such 'bicarbonate loading' provides an ergogenic strategy for sporting events involving high rates of anaerobic glycolysis which are otherwise limited by the body's capacity to manage the progressive increase in intracellular acidity. Studies show that bicarbonate loading strategies have a moderate positive effect on the performance of sports involving 1-7 min of sustained strenuous exercise, and may also be useful for prolonged sports involving intermittent or sustained periods of high-intensity work rates. This potential to enhance sports performance requires further investigation using appropriate research design, but may be limited by practical considerations such as gut discomfort or the logistics of the event. The effect of chronic use of bicarbonate supplementation prior to high-intensity workouts to promote better training performance and adaptations is worthy of further investigation. While this relatively simple dietary strategy has been studied and used by sports people for over 80 years, it is likely that there are still ways in which further benefits from bicarbonate supplementation can be developed and individualized for specific athletes or specific events. PMID:23765347

  18. Practical considerations in the development and application of reference levels

    International Nuclear Information System (INIS)

    Radiological exposures to the public during an accident that releases radioactive materials to the environment occur initially through the air pathway, secondly through a water pathway, and finally, through the food chain. From these exposure pathways, reference levels of radionuclides must be applied to limit public radiation doses. Such reference levels are difficult to develop and apply, particularly if the contaminants are transuranic elements such as plutonium. The reference level must be related to a resultant theoretical dose to the public through generic calculations. However, to permit rapid decisions after an accident, the reference levels need to be related to conditions or media in the environment that can be directly measured. They must also be tied to specific countermeasures such as sheltering, evacuation, or interdiction of drinking water or food supplies. This paper discusses the practical considerations in the development and application of reference levels for transuranic in the environment and the present capability to rapidly detect and quantify their concentrations following accidental contamination events. 16 refs., 3 tabs

  19. Practical consideration for electrokinetic remediation of contaminated soil

    Energy Technology Data Exchange (ETDEWEB)

    Hakimipour, M.; Elektorowicz, M. [Concordia Univ., Montreal, PQ (Canada). Dept. of Building Civil and Environmental Engineering

    2003-07-01

    Site remediation technology faces a particular challenge with soils contaminated by mixtures of contaminants that include both petroleum compounds and heavy metals. This paper describes electrokinetic remediation (also called electrokinetics), which has great potential for remediating such soils. A brief overview of electrokinetics was provided, and practical considerations in design criteria of the technology for field implementation were discussed. Several subsurface characteristics have an impact on the efficiency and extraction rate of contaminants. These characteristics include soil type, contaminant type and concentration, types of contaminant species and their solubility. The efficiency and cost effectiveness of this technology is greatly dependent on electrode material, configuration and electrode spacing. The technology is not significantly limited by soil type. It can be applied from clay to sand, and there is no limitation due to the concentration of contaminants. The simultaneous migration in soil of a mixture of different contaminants is possible with electrokinetics. The number of boreholes and installation costs can be reduced with larger electrode spacing, but the processing time is increased. 37 refs., 4 tabs., 1 fig.

  20. Omalizumab: Practical considerations regarding the risk of anaphylaxis

    Directory of Open Access Journals (Sweden)

    Kim Harold L

    2010-12-01

    Full Text Available Abstract Omalizumab has demonstrated efficacy among patients with moderate to severe persistent allergic asthma, whose symptoms are inadequately controlled with other controller agents. This therapy is generally well tolerated, but there are some safety considerations, the most important of which is the rare, but potentially life-threatening, occurrence of omalizumab-associated anaphylaxis. In Canada, data from the manufacturer of omalizumab indicate that the frequency of anaphylaxis attributed to Xolair in post-marketing use is approximately 0.2%. Other researchers, including the American Omalizumab Joint Task Force (OJTF, have suggested a lower overall frequency of 0.09%. This paper provides a summary of the epidemiologic research carried out to date and presents a concise, practical set of recommendations for the prevention, monitoring and management of omalizumab-associated anaphylaxis. Prevention tips include advice on patient education measures, concomitant medications and optimal administration. For the first three injections, the recommendation is to monitor in clinic for two hours after the omalizumab injection; for subsequent injections, the monitoring period should be 30 minutes or an appropriate time agreed upon by the individual patient and healthcare professional. In the event that a patient does experience omalizumab-associated anaphylaxis, the paper provides recommendations for handling the situation in-clinic and recommendations on how to counsel patients to recognize the potential signs and symptoms in the community and react appropriately.

  1. BROOKHAVEN: Booster commissioned

    International Nuclear Information System (INIS)

    The construction and first commissioning phase of the Booster synchrotron to inject into Brookhaven's veteran Alternating Gradient Synchrotron (AGS) were completed last year. Scheduled to come into operation this year, the new Booster will extend the research capabilities AGS, and with its ability to accelerate partially stripped heavy ions will play an essential role in the chain of accelerators serving the Relativistic Heavy Ion Collider (RHIC)

  2. An Analysis of Ethical Considerations in Programme Design Practice

    Science.gov (United States)

    Govers, Elly

    2014-01-01

    Ethical considerations are inherent to programme design decision-making, but not normally explicit. Nonetheless, they influence whose interests are served in a programme and who benefits from it. This paper presents an analysis of ethical considerations made by programme design practitioners in the context of a polytechnic in Aotearoa/New Zealand.…

  3. Integrated Crop/Livestock Systems Research: Practical research considerations

    Science.gov (United States)

    There are many reasons for the paucity of integrated crop/livestock research and associated publications. Integrated/crop livestock experiments that involve adequate treatments and replications, as perceived by both crop and animal scientists, require large acreages, many animals, considerable labor...

  4. Omalizumab: Practical considerations regarding the risk of anaphylaxis

    OpenAIRE

    Kim Harold L; Leigh Richard; Becker Allan

    2010-01-01

    Abstract Omalizumab has demonstrated efficacy among patients with moderate to severe persistent allergic asthma, whose symptoms are inadequately controlled with other controller agents. This therapy is generally well tolerated, but there are some safety considerations, the most important of which is the rare, but potentially life-threatening, occurrence of omalizumab-associated anaphylaxis. In Canada, data from the manufacturer of omalizumab indicate that the frequency of anaphylaxis attribut...

  5. Feedback Control Systems Loop Shaping Design with Practical Considerations

    Science.gov (United States)

    Kopsakis, George

    2007-01-01

    This paper describes loop shaping control design in feedback control systems, primarily from a practical stand point that considers design specifications. Classical feedback control design theory, for linear systems where the plant transfer function is known, has been around for a long time. But it s still a challenge of how to translate the theory into practical and methodical design techniques that simultaneously satisfy a variety of performance requirements such as transient response, stability, and disturbance attenuation while taking into account the capabilities of the plant and its actuation system. This paper briefly addresses some relevant theory, first in layman s terms, so that it becomes easily understood and then it embarks into a practical and systematic design approach incorporating loop shaping design coupled with lead-lag control compensation design. The emphasis is in generating simple but rather powerful design techniques that will allow even designers with a layman s knowledge in controls to develop effective feedback control designs.

  6. [Ambulatory surgery in France: practical and medicolegal considerations].

    Science.gov (United States)

    Wodey, E; de la Brière, F

    2013-12-01

    In France, ambulatory anaesthesia and surgery seem to be well codified. Many recommendations have been published by the Health Authority and the professional associations: they are summarized in this review. However, numerous practical problems persist: for example, two situations specific to paediatric practice are problematic parental comprehension and application of the information provided and poor access to strong analgesics outside the hospital. Despite this, the paediatric population is an ideal target for ambulatory care because of its usual good health and quicker recovery after minor injury as proven by the small percentage of failure and readmission. PMID:24209990

  7. Practical Considerations for Using Exploratory Factor Analysis in Educational Research

    Science.gov (United States)

    Beavers, Amy S.; Lounsbury, John W.; Richards, Jennifer K.; Huck, Schuyler W.; Skolits, Gary J.; Esquivel, Shelley L.

    2013-01-01

    The uses and methodology of factor analysis are widely debated and discussed, especially the issues of rotational use, methods of confirmatory factor analysis, and adequate sample size. The variety of perspectives and often conflicting opinions can lead to confusion among researchers about best practices for using factor analysis. The focus of the…

  8. Practical Considerations in the Interview and Evaluation of Sexual Offenders

    Science.gov (United States)

    Clipson, Clark R.

    2003-01-01

    The evaluation and assessment of sexual offenders is different than any other type of evaluation, and most clinicians are not properly trained to interview this population. This article addresses the clinical and ethical issues particular to the interview, assessment, and evaluation of these types of offenders. It offers both practical information…

  9. Ideology and community social psychology: theoretical considerations and practical implications.

    Science.gov (United States)

    Montenegro, Marisela

    2002-08-01

    This paper addresses the importance of the concept of ideology in community work. The implications of a Marxist approach to ideology in community practice are analyzed in terms of the concepts of problematization (P. Freire, 1979) and consciousness-raising (J. Barreiro, 1976), illustrating the point with some examples. The traditional Marxist perspective is also examined in relation to the perspectives of social constructionism (I. Ibáñez, 1996), cultural studies (A. McRobbie, 1992), post-Marxism (E. Laclau & C. Mouffe, 1985), and feminism (D. Haraway, 1991). It is argued that the concepts of hegemony and habitus (P. Bourdieu, 1985) can be useful to community social psychology theory and practice. A "situated perspective"--in which it is possible to dialogue from different "subject positions," and articulate transformation and political action--is argued. The implications of this shifting in the concept of ideology by means of theoretical developments outside social communitypsychology can help to define the external (outside) agent's position in community practice. PMID:12125780

  10. BROOKHAVEN: Booster boost

    International Nuclear Information System (INIS)

    After three months of intensive dedicated machine studies, Brookhaven's new Booster accelerated 5 x 1013 protons over four cycles, about 85% of the design intensity. This was made possible by careful matching of Linac beam into the Booster and by extensive resonance stop band corrections implemented during Booster acceleration. The best single cycle injection into the AGS Alternating Gradient Synchrotron was 1.14 x 1013 protons from the Booster. 1.05 x 1013 protons were kept in the AGS, a 92% combined efficiency of extraction, transfer, and injection. The maximum injected 1994 shutdown period, enabling the 1994 physics run to make use of the full Booster intensity and go for the stated AGS objective of 4x1013 protons per pulse

  11. Starting a business as a nurse consultant: practical considerations.

    Science.gov (United States)

    Papp, E M

    2000-03-01

    Nursing experience translates well to self employment in the occupational and environmental health field. However, nurses must conduct a self assessment to determine whether owning a business is a good fit for their personality and work style. Exploring which services to offer is the next step in starting a business and consists of determining not only which service to offer (e.g., writing policies or protocols, providing clinical services) but also which type of consultation model to use (i.e., purchase of expertise, doctor/client, process consultation). Every business must have a plan. A business plan is essential to starting a business. It solidifies the entrepreneur's focus, lays the foundation for the business, provides a tool for evaluating success, and is a strong tool for soliciting financial support. The name of the business is an important consideration because it is often the first contact the customers have with the occupational health nurse consultant. The name must be descriptive, appropriate, and memorable. PMID:10846971

  12. Case study 1. Practical considerations with experimental design and interpretation.

    Science.gov (United States)

    Barr, John T; Flora, Darcy R; Iwuchukwu, Otito F

    2014-01-01

    At some point, anyone with knowledge of drug metabolism and enzyme kinetics started out knowing little about these topics. This chapter was specifically written with the novice in mind. Regardless of the enzyme one is working with or the goal of the experiment itself, there are fundamental components and concepts of every experiment using drug metabolism enzymes. The following case studies provide practical tips, techniques, and answers to questions that may arise in the course of conducting such experiments. Issues ranging from assay design and development to data interpretation are addressed. The goal of this section is to act as a starting point to provide the reader with key questions and guidance while attempting his/her own work. PMID:24523122

  13. Scale and Governance: Conceptual Considerations and Practical Implications

    Directory of Open Access Journals (Sweden)

    Tom (A.. Veldkamp

    2011-06-01

    Full Text Available Policies have many unforeseen impacts on social-ecological systems at different levels of spatial and temporal scales. Partly because of this, both scale and governance have been and continue to be hotly debated and studied topics within many scientific disciplines. Although there are two distinct vocabularies, both communities seem to be struggling to come to terms with a shift that has common elements. This special feature has two types of contributions, three scoping papers, providing a state-of-the-art overview of the conceptual discussion, and six case study papers that set out to deal with the practicalities of combining scale and governance. The scoping papers strongly indicate that using the notion of complex systems, specifically the social-ecological system, is needed to improve the understanding of scale and governance. They furthermore confirm that both communities are shifting. Additionally, the papers show several promising ways forward to link scale and governance, even though they differ in their suggestions on most important courses of action and research agendas. The case study papers show that conceptual advances have not been taken up to their full extent in practice. Importantly, none of the papers is being very specific on the definition of the term governance. Additionally, most attention is given to spatial, temporal, and jurisdictional scales, largely ignoring, for example, network and knowledge scales. What is urgently needed are more case study papers that explicitly make use of the conceptual literature and through that attempt to link scale and governance. Ultimately, there is a challenge to more effectively include nonscientists in the debate. A transdisciplinary arena is required where the concepts of scale and governance are framed such that a broad variety of stakeholders can join the debate and/or the decision making process.

  14. Practical Considerations for Optic Nerve Estimation in Telemedicine

    Energy Technology Data Exchange (ETDEWEB)

    Karnowski, Thomas Paul [ORNL; Aykac, Deniz [ORNL; Chaum, Edward [ORNL; Giancardo, Luca [ORNL; Li, Yaquin [University of Tennessee, Knoxville (UTK); Tobin Jr, Kenneth William [ORNL

    2009-01-01

    The projected increase in diabetes in the United States and worldwide has created a need for broad-based, inexpensive screening for diabetic retinopathy (DR), an eye disease which can lead to vision impairment. A telemedicine network with retina cameras and automated quality control, physiological feature location, and lesion / anomaly detection is a low-cost way of achieving broad-based screening. In this work we report on the effect of quality estimation on an optic nerve (ON) detection method with a confidence metric. We report on an improvement of the fusion technique using a data set from an ophthalmologists practice then show the results of the method as a function of image quality on a set of images from an on-line telemedicine network collected in Spring 2009 and another broad-based screening program. We show that the fusion method, combined with quality estimation processing, can improve detection performance and also provide a method for utilizing a physician-in-the-loop for images that may exceed the capabilities of automated processing.

  15. Transverse beam dampers for the Brookhaven AGS

    International Nuclear Information System (INIS)

    A wide band damper system has been developed for the Brookhaven Alternating Gradient Synchrotron (AGS). The system consists of two sets of PUE pickups, analog and digital processing electronics, four 500 Watt wide band power amplifiers, and two pairs of strip line deflectors. The system is currently used to damp transverse coherent instabilities and injection errors, in both planes, for protons and all species of Heavy Ions. This paper discusses the system design and operation, focusing on the engineering considerations and problems encountered in the actual implementation. Operational data from both protons and Heavy Ion beams is presented

  16. Evidence-Based Practices in Classroom Management: Considerations for Research to Practice

    Science.gov (United States)

    Simonsen, Brandi; Fairbanks, Sarah; Briesch, Amy; Myers, Diane; Sugai, George

    2008-01-01

    Classroom management is a critical skill area. Teachers should be trained and supported in implementing practices that are likely to be successful; that is, practices that are backed by evidence. The purpose of this paper is to describe the outcomes of a systematic literature search conducted to identify evidence-based classroom management…

  17. Brookhaven highlights, 1986-1987

    International Nuclear Information System (INIS)

    The highlights of research conducted between October 1985 and September 1987 at Brookhaven National Laboratory are reviewed in this publication. Also covered are the administrative and financial status of the laboratory and a brief mention of meetings held and honors received. (FI)

  18. Brookhaven leak reactor to close

    CERN Multimedia

    MacIlwain, C

    1999-01-01

    The DOE has announced that the High Flux Beam Reactor at Brookhaven is to close for good. Though the news was not unexpected researchers were angry the decision had been taken before the review to assess the impact of reopening the reactor had been concluded (1 page).

  19. Hypernuclear physics research at Brookhaven

    International Nuclear Information System (INIS)

    This paper describes the results of a recently completed study of the hypernucleus 12/sub Λ/C. The observed formation of hypernuclear states at large momentum is compared with theoretical expectations. Future directions of the research program at Brookhaven are outlined

  20. The Brookhaven Accelerator Test Facility

    International Nuclear Information System (INIS)

    The Accelerator Test Facility (ATF), presently under construction at Brookhaven National laboratory, is described. It consists of a 50-MeV electron beam synchronizable to a high-peak power CO2 laser. The interaction of electrons with the laser field will be probed, with some emphasis on exploring laser-based acceleration techniques. 5 refs., 2 figs

  1. The Doing of Philosophy in the Music Class: Some Practical Considerations--Response to Bennett Reimer

    Science.gov (United States)

    Reichling, Mary J.

    2005-01-01

    A reply to Bennett Reimer's "The Doing of Philosophy in the Music Class: Some Practical Considerations" is presented. How the author of this article responds to Reimer's challenge depends in part on how they define philosophy in this context. Their thinking about music occurs in at least two different ways. She suggests that music possesses both…

  2. Researching Lesbian, Gay, and Bisexual Youth: Conceptual, Practical, and Ethical Considerations

    Science.gov (United States)

    D'Augelli, Anthony R.; Grossman, Arnold H.

    2006-01-01

    Developmental and educational researchers have overlooked the development of sexual orientation among adolescents and youth, even as they study sexual development and identity development during adolescence. This paper examines some conceptual, practical, and ethical considerations involved in conducting research on lesbian, gay, and bisexual…

  3. Brookhaven - going for gold

    International Nuclear Information System (INIS)

    Experiments using polarized (spin oriented) protons have a promising future at the Laboratory. Polarized sources are being improved considerably, and the advent of the Booster will enable accumulation of polarized beams before injection into the main ring. Adding these factors together indicates the possibility of colliding polarized proton beams in the proposed RHIC collider (of which more later) with a luminosity as high as 1032 and an energy of 350 GeV. The newcomer to the programme at the AGS is the series of experiments with light ion beams drawn from the nearby tandem. These began last October with oxygen-8 and silicon-14 beams at energies up to 15 GeV per nucleon and 5x108 accelerated ions per pulse for oxygen. (orig./HSI).

  4. Scientists at Brookhaven contribute to the development of a better electron accelerator

    CERN Multimedia

    2004-01-01

    Scientists working at Brookhaven have developed a compact linear accelerator called STELLA (Staged Electron Laser Acceleration). Highly efficient, it may help electron accelerators become practical tools for applications in industry and medicine, such as radiation therapy (1 page)

  5. Brookhaven fastbus/unibus interface

    Energy Technology Data Exchange (ETDEWEB)

    Benenson, G.; Bauernfeind, J.; Larsen, R.C.; Leipuner, L.B.; Morse, W.M.; Adair, R.K.; Black, J.K.; Campbell, S.R.; Kasha, H.; Schmidt, M.P.

    1983-01-01

    A typical high energy physics experiment requires both a high speed data acquisition and processing system, for data collection and reduction; and a general purpose computer to handle further reduction, bookkeeping and mass storage. Broad differences in architecture, format or technology, will often exist between these two systems, and interface design can become a formidable task. The PDP-11 series minicomputer is widely used in physics research, and the Brookhaven FASTBUS is the only standard high speed data acquisition system which is fully implemented in a current high energy physics experiment. This paper will describe the design and operation of an interface between these two systems. The major issues are elucidated by a preliminary discussion on the basic principles of Bus Systems, and their application to Brookhaven FASTBUS and UNIBUS.

  6. Brookhaven fastbus/unibus interface

    International Nuclear Information System (INIS)

    A typical high energy physics experiment requires both a high speed data acquisition and processing system, for data collection and reduction; and a general purpose computer to handle further reduction, bookkeeping and mass storage. Broad differences in architecture, format or technology, will often exist between these two systems, and interface design can become a formidable task. The PDP-11 series minicomputer is widely used in physics research, and the Brookhaven FASTBUS is the only standard high speed data acquisition system which is fully implemented in a current high energy physics experiment. This paper will describe the design and operation of an interface between these two systems. The major issues are elucidated by a preliminary discussion on the basic principles of Bus Systems, and their application to Brookhaven FASTBUS and UNIBUS

  7. Assessment and d/Deaf and Hard of Hearing Multilingual Learners: Considerations and Promising Practices.

    Science.gov (United States)

    Pizzo, Lianna; Chilvers, Amanda

    2016-01-01

    The authors address considerations and promising practices relating to assessment of d/Deaf and Hard of Hearing Multilingual Learners. DMLs' unique culture(s), language(s), and learning needs must be considered when assessments of this population are being planned, conducted, and interpreted. The authors address theory and research on (a) general considerations for the overarching assessment process, (b) specific assessment approaches used to assess DMLs, and (c) assessment of language proficiency for diverse language learners. In addition, basic recommendations for the assessment of DMLs are made, including increased availability of assessments in various languages, use of multiple sources of individual and family data, assessment of all languages, and incorporation of a strong assessment component (that includes nondiscrimination practices) into teacher preparation programs. PMID:27156918

  8. Current Practices in Global/International Advanced Pharmacy Practice Experiences: Home/Host Country or Site/Institution Considerations

    Science.gov (United States)

    Dakkuri, Adnan; Abrons, Jeanine P.; Williams, Dennis; Ombengi, David N.; Zheng, HaiAn; Al-Dahir, Sara; Tofade, Toyin; Gim, Suzanna; O’Connell, Mary Beth; Ratka, Anna; Dornblaser, Emily

    2016-01-01

    International outreach by schools and colleges of pharmacy is increasing. In this paper, we provide current practice guidelines to establish and maintain successful global/international advanced pharmacy practice experiences (G/I APPEs) with specific recommendations for home/host country and host site/institution. The paper is based on a literature review (2000-2014) in databases and Internet searches with specific keywords or terms. Educational documents such as syllabi and memoranda of understanding (MoUs) from pharmacy programs were also examined. In addition, a preliminary draft was developed and the findings and recommendations were reviewed in a 90-minute roundtable discussion at the 2014 American Association of Colleges of Pharmacy Annual Meeting. Recommendations for the host country include travel considerations (eg, passport, visa, air travel), safety, housing, transportation, travel alerts and warnings, health issues, and financial considerations. For the home country, considerations for establishment of G/I APPE site (eg, vetting process, MoU, site expectations) are described. The paper is a resource for development of new G/I APPEs and provides guidance for continuous quality improvement of partnerships focusing on G/I pharmacy education. PMID:27170809

  9. Current Practices in Global/International Advanced Pharmacy Practice Experiences: Home/Host Country or Site/Institution Considerations.

    Science.gov (United States)

    Alsharif, Naser Z; Dakkuri, Adnan; Abrons, Jeanine P; Williams, Dennis; Ombengi, David N; Zheng, HaiAn; Al-Dahir, Sara; Tofade, Toyin; Gim, Suzanna; O'Connell, Mary Beth; Ratka, Anna; Dornblaser, Emily

    2016-04-25

    International outreach by schools and colleges of pharmacy is increasing. In this paper, we provide current practice guidelines to establish and maintain successful global/international advanced pharmacy practice experiences (G/I APPEs) with specific recommendations for home/host country and host site/institution. The paper is based on a literature review (2000-2014) in databases and Internet searches with specific keywords or terms. Educational documents such as syllabi and memoranda of understanding (MoUs) from pharmacy programs were also examined. In addition, a preliminary draft was developed and the findings and recommendations were reviewed in a 90-minute roundtable discussion at the 2014 American Association of Colleges of Pharmacy Annual Meeting. Recommendations for the host country include travel considerations (eg, passport, visa, air travel), safety, housing, transportation, travel alerts and warnings, health issues, and financial considerations. For the home country, considerations for establishment of G/I APPE site (eg, vetting process, MoU, site expectations) are described. The paper is a resource for development of new G/I APPEs and provides guidance for continuous quality improvement of partnerships focusing on G/I pharmacy education. PMID:27170809

  10. The use of intelligent modules in Brookhaven FASTBUS

    International Nuclear Information System (INIS)

    Many considerations go into the design of modules for data acquisition. I address some of the more general aspects of this rather than the specifics of a particular design. The experience gained from using Brookhaven Fastbus in two finished experiments and one eminent one is used as a guide for these remarks. The physical size of modules used by Brookhaven Fastbus is such that the number of channels that can be handled is generally limited by front panel space, or front end layout logistics rather than area. One of the effects of large scale integrated circuits is that the cost of computational elements is relatively small. This, plus the space consideration, allows the assignment of low level data processing to the acquisition modules. Since these elements operate in parallel there is an obvious speed advantage

  11. Brookhaven Highlights, January 1982-March 1983

    Energy Technology Data Exchange (ETDEWEB)

    Kuper, J.B.H.; Rustad, M.C. (eds.)

    1983-01-01

    Research at Brookhaven National Laboratory is summarized. Major headings are high energy physics, physics and chemistry, life sciences, applied energy science, support activities and administration. (GHT)

  12. Clinical use of amyloid-positron emission tomography neuroimaging: Practical and bioethical considerations.

    Science.gov (United States)

    Witte, Michael M; Foster, Norman L; Fleisher, Adam S; Williams, Monique M; Quaid, Kimberly; Wasserman, Michael; Hunt, Gail; Roberts, J Scott; Rabinovici, Gil D; Levenson, James L; Hake, Ann Marie; Hunter, Craig A; Van Campen, Luann E; Pontecorvo, Michael J; Hochstetler, Helen M; Tabas, Linda B; Trzepacz, Paula T

    2015-09-01

    Until recently, estimation of β-amyloid plaque density as a key element for identifying Alzheimer's disease (AD) pathology as the cause of cognitive impairment was only possible at autopsy. Now with amyloid-positron emission tomography (amyloid-PET) neuroimaging, this AD hallmark can be detected antemortem. Practitioners and patients need to better understand potential diagnostic benefits and limitations of amyloid-PET and the complex practical, ethical, and social implications surrounding this new technology. To complement the practical considerations, Eli Lilly and Company sponsored a Bioethics Advisory Board to discuss ethical issues that might arise from clinical use of amyloid-PET neuroimaging with patients being evaluated for causes of cognitive decline. To best address the multifaceted issues associated with amyloid-PET neuroimaging, we recommend this technology be used only by experienced imaging and treating physicians in appropriately selected patients and only in the context of a comprehensive clinical evaluation with adequate explanations before and after the scan. PMID:27239516

  13. Practical, ethical and regulatory considerations for the evolving medical and research genomics landscape

    Directory of Open Access Journals (Sweden)

    Gholson J. Lyon

    2013-12-01

    Full Text Available Recent advances in sequencing technology are making possible the application of large-scale genomic analyses to individualized care, both in wellness and disease. However, a number of obstacles remain before genomic sequencing can become a routine part of clinical practice. One of the more significant and underappreciated is the lack of consensus regarding the proper environment and regulatory structure under which clinical genome sequencing and interpretation should be performed. The continued reliance on pure research vs. pure clinical models leads to problems for both research participants and patients in an era in which the lines between research and clinical practice are becoming increasingly blurred. Here, we discuss some of the ethical, regulatory and practical considerations that are emerging in the field of genomic medicine. We also propose that many of the cost and safety issues we are facing can be mitigated through expanded reliance on existing clinical regulatory frameworks and the implementation of distributive work-sharing strategies designed to leverage the strengths of our genomics centers and clinical interpretive teams.

  14. Pushing beyond resistors and constipators: implementation considerations for infection prevention best practices.

    Science.gov (United States)

    Bearman, Gonzalo; Stevens, Michael P

    2014-01-01

    Despite increased knowledge in the science of infection prevention, the implementation of evidence-based best practices remains a challenge. The dissemination of infection prevention risk reduction best practices should be approached with flexibility and a collaborative perspective. High-quality evidence and cost assessments to support interventions are important initial considerations. An implementation framework should be contextually appropriate, take into account an organization's culture, and be mindful of an approach that minimizes complexity. Trialing an intervention within a specific unit may later lead to increased uptake organization wide. Highly functional collaborations with effective leaders are needed for successful implementation. Leadership for infection prevention initiatives may include upper level management; however, hospital epidemiologists and infection preventionists often play this role. Although published data fail to identify a single best integrative strategy for infection prevention practice change, success has been associated with education initiatives and seminars, audit and feedback, distribution of educational materials, marketing, mass media, positive deviance, and the employment of champions, facilitators, role models, and opinion leaders. Local personnel, such as organizational resistors and constipators, can be barriers to idea dissemination and implementation. In addition to a thoughtfully conceived implementation strategy, dealing with infection prevention resistors and constipators includes getting their buy-in early in the dissemination process, working around them, or terminating their employment. More data are needed to best define which infection prevention dissemination strategies are most effective. PMID:24407546

  15. Guide to nondestructive assay standards: Preparation criteria, availability, and practical considerations

    Energy Technology Data Exchange (ETDEWEB)

    Hsue, S.T.; Stewart, J.E.; Sampson, T.E.; Butler, G.W.; Rudy, C.R.; Rinard, P.M.

    1997-10-01

    For certification and measurement control, nondestructive assay (NDA) instruments and methods used for verification measurements of special nuclear materials (SNMs) require calibrations based on certified reference materials (CRMs), or working reference materials (WRMs), traceable to the national system of measurements, and adequately characteristic of the unknowns. The Department of Energy Office of Safeguards and Security is sponsoring production of a comprehensive guide to preparation of NDA standards. The scope of the report includes preparation criteria, current availability of CRMs and WRMs, practical considerations for preparation and characterization, and an extensive bibliography. In preparing the report, based primarily on experience at Los Alamos, they have found that standards preparation is highly dependent on the particular NDA method being applied. They therefore include sections that contain information specific to commonly used neutron and gamma-ray NDA techniques. They also present approaches that are alternatives to, or minimize requirements for physical standards.

  16. Practical Considerations For A Design Of A High Precision 3-D Laser Scanner System

    Science.gov (United States)

    Blais, Francois; Rioux, Marc; Beraldin, J.-Angelo

    1988-11-01

    The Laboratory for Intelligent Systems of the Division of Electrical Engineering of the National Research Council of Canada is intensively involved in the development of laser-based three-dimensional vision systems and their applications. Two basic systems have been invented. One, based on a double aperture mask in front of a CCD camera, has been developed for robotic applications and control. The other technique is based on an auto-synchronized scanning principle to provide accurate, fast, and reliable 3-D coordinates. Using the latter method, several prototypes have been developed for the acquisition of 3-D data of objects and for inspection. This paper will describe some practical considerations for the design and implementation of triangulation-based 3-D range sensors with emphasis on the latter triangulation technique. Some applications and results will be presented.

  17. Guide to nondestructive assay standards: Preparation criteria, availability, and practical considerations

    International Nuclear Information System (INIS)

    For certification and measurement control, nondestructive assay (NDA) instruments and methods used for verification measurement of special nuclear materials (SNMs) require calibrations based on certified reference materials (CRMs), or working reference materials (WRMs), traceable to the national system of measurements, and adequately characteristic of the unknowns. The Department of Energy Office of Safeguards and Security is sponsoring production of a comprehensive guide to preparation of NDA standards. The scope of the report includes preparation criteria, current availability of CRMs and WRMs, practical considerations for preparation and characterization, and an extensive bibliography. In preparing the report, based primarily on experience at Los Alamos, we have found that standards preparation is highly dependent on the particular NDA method being applied. We therefore include sections that contain information specific to commonly used neutron and gamma-ray NDA techniques. 16 refs., 4 figs., 2 tabs

  18. Grading Practices and Considerations of Graduate Students at the Beginning of their Teaching Assignment

    CERN Document Server

    Yerushalmi, Edit; Maries, Alexandru; Henderson, Charles R; Singh, Chandralekha

    2016-01-01

    Research shows that expert-like approaches to problem-solving can be promoted by encouraging students to explicate their thought processes and follow a prescribed problem-solving strategy. Since grading communicates instructors' expectations, teaching assistants' grading decisions play a crucial role in forming students' approaches to problem-solving in physics. We investigated the grading practices and considerations of 43 graduate teaching assistants (TAs). The TAs were asked to grade a set of specially designed student solutions and explain their grading decisions. We found that in a quiz context, a majority of TAs noticed but did not grade on solution features which promote expert-like approaches to problem-solving. In addition, TAs graded differently in quiz and homework contexts, partly because of how they considered time limitations in a quiz. Our findings can inform professional development programs for TAs.

  19. Guide to nondestructive assay standards: Preparation criteria, availability, and practical considerations

    International Nuclear Information System (INIS)

    For certification and measurement control, nondestructive assay (NDA) instruments and methods used for verification measurements of special nuclear materials (SNMs) require calibrations based on certified reference materials (CRMs), or working reference materials (WRMs), traceable to the national system of measurements, and adequately characteristic of the unknowns. The Department of Energy Office of Safeguards and Security is sponsoring production of a comprehensive guide to preparation of NDA standards. The scope of the report includes preparation criteria, current availability of CRMs and WRMs, practical considerations for preparation and characterization, and an extensive bibliography. In preparing the report, based primarily on experience at Los Alamos, they have found that standards preparation is highly dependent on the particular NDA method being applied. They therefore include sections that contain information specific to commonly used neutron and gamma-ray NDA techniques. They also present approaches that are alternatives to, or minimize requirements for physical standards

  20. A field ornithologist’s guide to genomics: Practical considerations for ecology and conservation

    Science.gov (United States)

    Oyler-McCance, Sara J.; Oh, Kevin; Langin, Kathryn; Aldridge, Cameron

    2016-01-01

    Vast improvements in sequencing technology have made it practical to simultaneously sequence millions of nucleotides distributed across the genome, opening the door for genomic studies in virtually any species. Ornithological research stands to benefit in three substantial ways. First, genomic methods enhance our ability to parse and simultaneously analyze both neutral and non-neutral genomic regions, thus providing insight into adaptive evolution and divergence. Second, the sheer quantity of sequence data generated by current sequencing platforms allows increased precision and resolution in analyses. Third, high-throughput sequencing can benefit applications that focus on a small number of loci that are otherwise prohibitively expensive, time-consuming, and technically difficult using traditional sequencing methods. These advances have improved our ability to understand evolutionary processes like speciation and local adaptation, but they also offer many practical applications in the fields of population ecology, migration tracking, conservation planning, diet analyses, and disease ecology. This review provides a guide for field ornithologists interested in incorporating genomic approaches into their research program, with an emphasis on techniques related to ecology and conservation. We present a general overview of contemporary genomic approaches and methods, as well as important considerations when selecting a genomic technique. We also discuss research questions that are likely to benefit from utilizing high-throughput sequencing instruments, highlighting select examples from recent avian studies.

  1. Practical considerations and patient selection for intrathecal drug delivery in the management of chronic pain.

    Science.gov (United States)

    Saulino, Michael; Kim, Philip S; Shaw, Erik

    2014-01-01

    Chronic pain continues to pose substantial and growing challenges for patients, caregivers, health care professionals, and health care systems. By the time a patient with severe refractory pain sees a pain specialist for evaluation and management, that patient has likely tried and failed several nonpharmacologic and pharmacologic approaches to pain treatment. Although relegated to one of the interventions of "last resort", intrathecal drug delivery can be useful for improving pain control, optimizing patient functionality, and minimizing the use of systemic pain medications in appropriately selected patients. Due to its clinical and logistical requirements, however, intrathecal drug delivery may fit poorly into the classic pain clinic/interventional model and may be perceived as a "critical mass" intervention that is feasible only for large practices that have specialized staff and appropriate office resources. Potentially, intrathecal drug delivery may be more readily adopted into larger practices that can commit the necessary staff and resources to support patients' needs through the trialing, initiation, monitoring, maintenance, and troubleshooting phases of this therapy. Currently, two agents - morphine and ziconotide - are approved by the United States Food and Drug Administration for long-term intrathecal delivery. The efficacy and safety profiles of morphine have been assessed in long-term, open-label, and retrospective studies of >400 patients with chronic cancer and noncancer pain types. The efficacy and safety profiles of ziconotide have been assessed in three double-blind, placebo-controlled trials of 457 patients, and safety has been assessed in 1,254 patients overall, with severe chronic cancer, noncancer, and acquired immunodeficiency syndrome pain types. Both agents are highlighted as first-line intrathecal therapy for the management of neuropathic or nociceptive pain. The purpose of this review is to discuss practical considerations for intrathecal

  2. Practical considerations and patient selection for intrathecal drug delivery in the management of chronic pain

    Science.gov (United States)

    Saulino, Michael; Kim, Philip S; Shaw, Erik

    2014-01-01

    Chronic pain continues to pose substantial and growing challenges for patients, caregivers, health care professionals, and health care systems. By the time a patient with severe refractory pain sees a pain specialist for evaluation and management, that patient has likely tried and failed several nonpharmacologic and pharmacologic approaches to pain treatment. Although relegated to one of the interventions of “last resort”, intrathecal drug delivery can be useful for improving pain control, optimizing patient functionality, and minimizing the use of systemic pain medications in appropriately selected patients. Due to its clinical and logistical requirements, however, intrathecal drug delivery may fit poorly into the classic pain clinic/interventional model and may be perceived as a “critical mass” intervention that is feasible only for large practices that have specialized staff and appropriate office resources. Potentially, intrathecal drug delivery may be more readily adopted into larger practices that can commit the necessary staff and resources to support patients’ needs through the trialing, initiation, monitoring, maintenance, and troubleshooting phases of this therapy. Currently, two agents – morphine and ziconotide – are approved by the United States Food and Drug Administration for long-term intrathecal delivery. The efficacy and safety profiles of morphine have been assessed in long-term, open-label, and retrospective studies of >400 patients with chronic cancer and noncancer pain types. The efficacy and safety profiles of ziconotide have been assessed in three double-blind, placebo-controlled trials of 457 patients, and safety has been assessed in 1,254 patients overall, with severe chronic cancer, noncancer, and acquired immunodeficiency syndrome pain types. Both agents are highlighted as first-line intrathecal therapy for the management of neuropathic or nociceptive pain. The purpose of this review is to discuss practical considerations

  3. BROOKHAVEN NATIONAL LABORATORY WILDLIFE MANAGEMENT PLAN.

    Energy Technology Data Exchange (ETDEWEB)

    NAIDU,J.R.

    2002-10-22

    The purpose of the Wildlife Management Plan (WMP) is to promote stewardship of the natural resources found at the Brookhaven National Laboratory (BNL), and to integrate their protection with pursuit of the Laboratory's mission.

  4. Barrier Cavities in the Brookhaven AGS

    International Nuclear Information System (INIS)

    In collaboration with KEK two barrier cavities, each generating 40 kV per turn have been installed in the Brookhaven AGS. Machine studies are described and their implications for high intensity operations are discussed

  5. ATLAS Overview Week at Brookhaven

    CERN Multimedia

    Pilcher, J

    Over 200 ATLAS participants gathered at Brookhaven National Laboratory during the first week of June for our annual overview week. Some system communities arrived early and held meetings on Saturday and Sunday, and the detector interface group (DIG) and Technical Coordination also took advantage of the time to discuss issues of interest for all detector systems. Sunday was also marked by a workshop on the possibilities for heavy ion physics with ATLAS. Beginning on Monday, and for the rest of the week, sessions were held in common in the well equipped Berkner Hall auditorium complex. Laptop computers became the norm for presentations and a wireless network kept laptop owners well connected. Most lunches and dinners were held on the lawn outside Berkner Hall. The weather was very cooperative and it was an extremely pleasant setting. This picture shows most of the participants from a view on the roof of Berkner Hall. Technical Coordination and Integration issues started the reports on Monday and became a...

  6. The Brookhaven Radiation Effects Facility

    International Nuclear Information System (INIS)

    The Neutral Particle Beam (NPB) Radiation Effects Facility (REF), funded by the Strategic Defense Initiative Office (SDIO) through the Defense Nuclear Agency (DNA) and the Air Force Weapons Laboratory (AFWL), has been constructed at Brookhaven National Laboratory (BNL). Operation started in October 1986. The facility is capable of delivering pulsed H-, H/sup o/, and H+ beams of 100 to 200 MeV energy up to 30 mA peak current. Pulses can be adjusted from 5 μs to 500 μs length at a repetition rate of 5 pps. The beam spot on target is adjustable from 3 to 100 cm diameter (2 σ) resulting in a maximum dose of about 10 MRads (Si) per pulse (small beam spot). Experimental use of the REF is being primarily supported by the SDI lethality (LTH-4) program. The program has addressed ionization effects in electronics, both dose rate and total dose dependence, radiation-sensitive components, and dE/dx effects in energetic materials including propellants and high explosives (HE). This paper describes the facility, its capabilities and potential, and the experiments that have been carried out to date or are being planned. 2 refs., 10 figs

  7. Some practical considerations in finite element-based digital image correlation

    KAUST Repository

    Wang, Bo

    2015-04-20

    As an alternative to subset-based digital image correlation (DIC), finite element-based (FE-based) DIC method has gained increasing attention in the experimental mechanics community. However, the literature survey reveals that some important issues have not been well addressed in the published literatures. This work therefore aims to point out a few important considerations in the practical algorithm implementation of the FE-based DIC method, along with simple but effective solutions that can effectively tackle these issues. First, to better accommodate the possible intensity variations of the deformed images practically occurred in real experiments, a robust zero-mean normalized sum of squared difference criterion, instead of the commonly used sum of squared difference criterion, is introduced to quantify the similarity between reference and deformed elements in FE-based DIC. Second, to reduce the bias error induced by image noise and imperfect intensity interpolation, low-pass filtering of the speckle images with a 5×5 pixels Gaussian filter prior to correlation analysis, is presented. Third, to ensure the iterative calculation of FE-based DIC converges correctly and rapidly, an efficient subset-based DIC method, instead of simple integer-pixel displacement searching, is used to provide accurate initial guess of deformation for each calculation point. Also, the effects of various convergence criteria on the efficiency and accuracy of FE-based DIC are carefully examined, and a proper convergence criterion is recommended. The efficacy of these solutions is verified by numerical and real experiments. The results reveal that the improved FE-based DIC offers evident advantages over existing FE-based DIC method in terms of accuracy and efficiency. © 2015 Elsevier Ltd. All rights reserved.

  8. Practical considerations for enhanced-resolution coil-wrapped distributed temperature sensing

    Science.gov (United States)

    Hilgersom, Koen; van Emmerik, Tim; Solcerova, Anna; Berghuijs, Wouter; Selker, John; van de Giesen, Nick

    2016-05-01

    Fibre optic distributed temperature sensing (DTS) is widely applied in Earth sciences. Many applications require a spatial resolution higher than that provided by the DTS instrument. Measurements at these higher resolutions can be achieved with a fibre optic cable helically wrapped on a cylinder. The effect of the probe construction, such as its material, shape, and diameter, on the performance has been poorly understood. In this article, we study data sets obtained from a laboratory experiment using different cable and construction diameters, and three field experiments using different construction characteristics. This study shows that the construction material, shape, diameter, and cable attachment method can have a significant influence on DTS temperature measurements. We present a qualitative and quantitative approximation of errors introduced through the choice of auxiliary construction, influence of solar radiation, coil diameter, and cable attachment method. Our results provide insight into factors that influence DTS measurements, and we present a number of solutions to minimize these errors. These practical considerations allow designers of future DTS measurement set-ups to improve their environmental temperature measurements.

  9. Direct-Acting Oral Anticoagulants: Practical Considerations for Emergency Medicine Physicians

    Directory of Open Access Journals (Sweden)

    W. Frank Peacock

    2016-01-01

    Full Text Available Nonvalvular atrial fibrillation- (NVAF- related stroke and venous thromboembolism (VTE are cardiovascular diseases associated with significant morbidity and economic burden. The historical standard treatment of VTE has been the administration of parenteral heparinoid until oral warfarin therapy attains a therapeutic international normalized ratio. Warfarin has been the most common medication for stroke prevention in NVAF. Warfarin use is complicated by a narrow therapeutic window, unpredictable dose response, numerous food and drug interactions, and requirements for frequent monitoring. To overcome these disadvantages, direct-acting oral anticoagulants (DOACs—dabigatran, rivaroxaban, apixaban, and edoxaban—have been developed for the prevention of stroke or systemic embolic events (SEE in patients with NVAF and for the treatment of VTE. Advantages of DOACs include predictable pharmacokinetics, few drug-drug interactions, and low monitoring requirements. In clinical studies, DOACs are noninferior to warfarin for the prevention of NVAF-related stroke and the treatment and prevention of VTE as well as postoperative knee and hip surgery VTE prophylaxis, with decreased bleeding risks. This review addresses the practical considerations for the emergency physician in DOAC use, including dosing recommendations, laboratory monitoring, anticoagulation reversal, and cost-effectiveness. The challenges of DOACs, such as the lack of specific laboratory measurements and antidotes, are also discussed.

  10. Ethical and Practical Considerations in Removing Black Box Warnings from Drug Labels.

    Science.gov (United States)

    Yeh, James S; Sarpatwari, Ameet; Kesselheim, Aaron S

    2016-08-01

    Boxed warnings-also known as "black box" warnings-can be a powerful tool in communicating drug risks to physicians and patients. The overall number of boxed warnings has grown in recent years as the US Food and Drug Administration (FDA) has approved more drugs on the basis of limited pre-marketing information and as new safety issues for marketed drugs have been identified. Two recent manufacturers' petitions to remove boxed warnings on the drugs rosiglitazone (Avandia) and varenicline (Chantix) have led to divergent FDA decisions and revealed different considerations involved in boxed warning imposition and removal. For ethical and practical reasons, the FDA is justified in applying a higher standard for boxed warning removal than for imposition, as removal of a boxed warning may have unintended effects on physician and patient behavior. However, no guidelines on boxed warning removal currently exist. To promote safe use of approved prescription drugs, the FDA should adopt a uniform and transparent process governing decisions to impose or remove boxed warnings. PMID:27000800

  11. Practical considerations and patient selection for intrathecal drug delivery in the management of chronic pain

    Directory of Open Access Journals (Sweden)

    Saulino M

    2014-11-01

    assessed in three double-blind, placebo-controlled trials of 457 patients, and safety has been assessed in 1,254 patients overall, with severe chronic cancer, noncancer, and acquired immunodeficiency syndrome pain types. Both agents are highlighted as first-line intrathecal therapy for the management of neuropathic or nociceptive pain. The purpose of this review is to discuss practical considerations for intrathecal drug delivery, delineate criteria for the identification and selection of candidates for intrathecal drug delivery, and consider which agent may be more appropriate for individual patients. Keywords: review, patient selection, chronic pain, intrathecal, drug delivery

  12. Complementary tests in the assistance medical practice. Some useful considerations for the profes- sional formation of doctors.

    OpenAIRE

    Luis Alberto Corona Martínez

    2010-01-01

    In spite of the present contradictions about the place lab tests have in the medical assistance, to ignore this kind of tests in the medical practice would not be a way to touch the topic objectively. The aim of this article is to present some considerations about the use of lab tests in the medical practice , which are very useful for the new doctors in formations.

  13. Genetic Testing for Sports Performance, Responses to Training and Injury Risk: Practical and Ethical Considerations.

    Science.gov (United States)

    Williams, Alun G; Wackerhage, Henning; Day, Stephen H

    2016-01-01

    This paper addresses practical and ethical considerations regarding genetic tests to predict performance and/or risk of exercise-related injury or illness. Various people might wish to conduct sport-related genetic tests for a variety of reasons. For example, an individual might seek personal genetic information to help guide their own sport participation. A sports coach might wish to test young athletes to aid team selection or individualize training. A physician might want to predict the risk of injury or illness in athletes and advise regarding selection or preventative measures. An insurance company might seek to estimate the risk of career-threatening injury for athletes based partly on genetic information. Whilst this information is, in part, encoded in our DNA sequence, the available tests allow generally only a poor prediction of the aforementioned variables. In other words, the current genetic tests and analysis methods are not powerful enough to inform important decisions in sport to a substantial degree. It is particularly disappointing that more than half of the commercially available genetic tests related to exercise and sport do not appear to identify publicly the genetic variants they assess, making scrutiny by academic scholars and consumers (or their representatives) impossible. There are also challenging ethical issues to consider. For example, the imposition of genetic tests on individuals (especially young people) by third parties is potentially susceptible to abuse. Scientists and practitioners should understand the limitations of the tests currently available, the ethical concerns and the importance of counselling before and after testing so that they are only used in a responsible manner. PMID:27287080

  14. Measuring energy metabolism in the mouse – theoretical, practical and analytical considerations

    Directory of Open Access Journals (Sweden)

    JohnRogerSpeakman

    2013-03-01

    Full Text Available The mouse is one of the most important model organisms for understanding human genetic function and disease. This includes characterisation of the factors that influence energy expenditure and dysregulation of energy balance leading to obesity and its sequalae. Measuring energy metabolism in the mouse presents a challenge because the animals are small, and in this respect it presents similar challenges to measuring energy demands in many other species of small mammal. This paper considers some theoretical, practical and analytical considerations to be considered when measuring energy expenditure in mice. Theoretically total daily energy expenditure is comprised of several different components: basal or resting expenditure, physical activity, thermoregulation and the thermic effect of food. Energy expenditure in mice is normally measured using open flow indirect calorimetry apparatus. Two types of system are available – one of which involves a single small Spartan chamber linked to a single analyser, which is ideal for measuring the individual components of energy demand. The other type of system involves a large chamber which mimics the home cage environment and is generally configured with several chambers per analyser. These latter systems are ideal for measuring total daily energy expenditure but at present do not allow accurate decomposition of the total expenditure into its components. The greatest analytical challenge for mouse expenditure data is how to account for body size differences between individuals. This has been a matter of some discussion for at least 120 years. The statistically most appropriate approach is to use ANCOVA with individual aspects of body composition as independent predictors.

  15. Analytical Frameworks of Cooperative and Cognitive Radio Systems with Practical Considerations

    KAUST Repository

    Khan, Fahd Ahmed

    2013-08-01

    the performance of a network where two sources communicate with each other via fixed-gain amplify-and-forward relays is studied and for a Rayleigh faded channel, closed-form expressions for the outage probability (OP), moment generating function (MGF) and SER are derived. Relay location is also taken into consideration and it is shown that the performance can be improved by placing the relay closer to the source whose channel is more outdated. Some practical issues encountered in cognitive radio systems (CRS) are also investigated. The QoS of CRS can be improved through spatial diversity which can be achieved by either using multiple antennas or exploiting the independent channels of each user in a multi-user network. In this dissertation, both approaches are examined and in multi-antenna CRS, transmit antenna selection (TAS) is proposed where as in a multi-user CRS, user selection is proposed to achieve performance gains. TAS reduces the implementation cost and complexity and thus makes CRS more feasible. Additionally, unlike previous works, in accordance with real world systems, the transmitter is assumed to have limited peak transmit power. For both these schemes, considering practical channel models, closed-form expression for the OP performance, SER performance and ergodic capacity (EC) are obtained and the performance in the asymptotic regimes is also studied. Furthermore, the OP performance is also analyzed taking into account the interference from the primary network on the cognitive network.

  16. Articles on Practical Cybernetics. Computer-Developed Computers; Heuristics and Modern Sciences; Linguistics and Practice; Cybernetics and Moral-Ethical Considerations; and Men and Machines at the Chessboard.

    Science.gov (United States)

    Berg, A. I.; And Others

    Five articles which were selected from a Russian language book on cybernetics and then translated are presented here. They deal with the topics of: computer-developed computers, heuristics and modern sciences, linguistics and practice, cybernetics and moral-ethical considerations, and computer chess programs. (Author/JY)

  17. Practical considerations for maximizing heat production in a novel thermobrachytherapy seed prototype

    Energy Technology Data Exchange (ETDEWEB)

    Gautam, Bhoj; Warrell, Gregory; Shvydka, Diana; Ishmael Parsai, E., E-mail: e.parsai@utoledo.edu [University of Toledo Medical Center, 3000 Arlington Avenue, MS1151, Toledo, Ohio 43614 (United States); Subramanian, Manny [BEST Medical International, Inc., 7643 Fullerton Road, Springfield, Virginia 22153 (United States)

    2014-02-15

    images, and a preliminary experiment demonstrates thermal self-regulation and adequate heating of a tissue-mimicking phantom by seed prototypes. The effect of self-shielding of the seed against the external magnetic field is small, and only minor thermal stress is induced in heating of the seeds from room temperature to well above the seed operating temperature. With proper selection of magnetic field parameters, the thermal dose distribution of an arrangement of TB and hyperthermia-only seeds may be made to match with its radiation dose distribution. Conclusions: The presented analyses address several practical considerations for manufacturing of the proposed TB seeds and identify critical issues for the prototype implementation. The authors’ preliminary experiments demonstrate close agreement with the modeling results, confirming the feasibility of combining sources of heat and radiation into a single thermobrachytherapy seed.

  18. Practical considerations for maximizing heat production in a novel thermobrachytherapy seed prototype

    International Nuclear Information System (INIS)

    a preliminary experiment demonstrates thermal self-regulation and adequate heating of a tissue-mimicking phantom by seed prototypes. The effect of self-shielding of the seed against the external magnetic field is small, and only minor thermal stress is induced in heating of the seeds from room temperature to well above the seed operating temperature. With proper selection of magnetic field parameters, the thermal dose distribution of an arrangement of TB and hyperthermia-only seeds may be made to match with its radiation dose distribution. Conclusions: The presented analyses address several practical considerations for manufacturing of the proposed TB seeds and identify critical issues for the prototype implementation. The authors’ preliminary experiments demonstrate close agreement with the modeling results, confirming the feasibility of combining sources of heat and radiation into a single thermobrachytherapy seed

  19. Well-Being and Happiness: Critical, Practical and Philosophical Considerations for Policies and Practices in Lifelong Learning

    Science.gov (United States)

    Gouthro, Patricia A.

    2010-01-01

    This paper argues that while the Inquiry into the Future of Lifelong Learning that was commissioned by NIACE makes some helpful recommendations for broadening the scope of lifelong learning to include considerations around well-being and happiness, the reports do not provide a sufficiently critical or philosophical analysis of the challenges…

  20. Brookhaven highlights, October 1979-September 1980

    Energy Technology Data Exchange (ETDEWEB)

    1980-01-01

    Highlights are given for the research areas of the Brookhaven National Laboratory. These areas include high energy physics, physics and chemistry, life sciences, applied energy science (energy and environment, and nuclear energy), and support activities (including mathematics, instrumentation, reactors, and safety). (GHT)

  1. Brookhaven highlights, October 1979-September 1980

    International Nuclear Information System (INIS)

    Highlights are given for the research areas of the Brookhaven National Laboratory. These areas include high energy physics, physics and chemistry, life sciences, applied energy science (energy and environment, and nuclear energy), and support activities (including mathematics, instrumentation, reactors, and safety)

  2. Elastic neutrino electron scattering at Brookhaven

    International Nuclear Information System (INIS)

    A progress report is given of Experiment 734 at Brookhaven, with a focus on the elastic reactions nu/sub μ/ + e- → nu/sub μ/ + e- and anti nu/sub μ/ + e- → anti nu/sub μ/ + e-. The present status, recent results, and future plans are discussed

  3. Dr. Praveen Chaudhari named director of Brookhaven National Laboratory

    CERN Multimedia

    2003-01-01

    "Brookhaven Science Associates announced today the selection of Dr. Praveen Chaudhari as Director of the U.S. Department of Energy's Brookhaven National Laboratory. Dr. Chaudhari, who will begin his new duties on April 1, joins Brookhaven Lab after 36 years of distinguished service at IBM as a scientist and senior manager of research" (1 page).

  4. Possibilities for relativistic heavy ion collisions at Brookhaven

    International Nuclear Information System (INIS)

    Since 1980 there has been considerable interest at Brookhaven in exploiting the existence of the Colliding Beam Accelerator, CBA, earlier referred to as Isabelle, for the generation of heavy ion collisions at very high energies. The only requirement for a heavy ion collider would have been for an energy booster for the Tandem accelerator and a tunnel and magnet transport system to the AGS. For a few million dollars heavy ions up to nearly 200 GeV/amu could be collided with luminosities of 1027 to 1028/cm2 sec in experimental halls with ideal facilities for heavy ion physics studies. Although the CBA project has been stopped, it is still true that Brookhaven has in place enormous advantages for constructing a heavy ion collider. This paper describes a design that exploits those advantages. It uses the tunnel and other civil construction, the refrigerator, vacuum equipment, injection line components, and the magnet design for which there is expertise and a production facility in place. The result is a machine that appears quite different than would a machine designed from first principles without access to these resources but one which is of high performance and of very attractive cost

  5. Telerehabilitation Store and Forward Applications: A Review of Applications and Privacy Considerations in Physical and Occupational Therapy Practice

    OpenAIRE

    Christopher Peterson; Valerie Watzlaf

    2015-01-01

    An overview of store and forward applications commonly used in physical and occupational therapy practice is reviewed with respect to regulation, privacy, security, and clinical applications. A privacy and security checklist provides a clear reference of pertinent regulatory issues regarding these software applications. A case study format is used to highlight clinical applications of store and forward software features. Important considerations of successful implementation of store and forwa...

  6. Telerehabilitation Store and Forward Applications: A Review of Applications and Privacy Considerations in Physical and Occupational Therapy Practice

    Directory of Open Access Journals (Sweden)

    Christopher Peterson

    2015-01-01

    Full Text Available An overview of store and forward applications commonly used in physical and occupational therapy practice is reviewed with respect to regulation, privacy, security, and clinical applications. A privacy and security checklist provides a clear reference of pertinent regulatory issues regarding these software applications. A case study format is used to highlight clinical applications of store and forward software features. Important considerations of successful implementation of store and forward applications are also identified and discussed.

  7. Considerations Influencing Hispanic-American Mothers' Intergenerational Language Practices with Their Children with Autism

    Science.gov (United States)

    Niles, Gloria Y.

    2013-01-01

    Using basic qualitative research methodology, the purpose for this dissertation study was to explore the language, social and learning considerations and subsequent actions taken by eight, bilingual, Hispanic-American mothers of children with autism between the ages of four and eight-years-old regarding speaking Spanish, English or both languages…

  8. Counseling Psychology in the Era of Genetic Testing: Considerations for Practice, Research, and Training

    Science.gov (United States)

    Kaut, Kevin P.

    2006-01-01

    The field of genetics and the process of testing for genetic disorders have advanced considerably over the past half century, ushering in significant improvements in certain areas of medical diagnosis and disease prediction. However, genetic discoveries are accompanied by many social, emotional, and psychological implications, and counseling…

  9. A study of CALIS evaluation indicator system for digital resources and its practical application considerations

    Institute of Scientific and Technical Information of China (English)

    XIAO; Long; LI; Haoling; XU; Cheng

    2008-01-01

    Based on our theoretical studies and practical experience related to the digital resource evaluation activities,which were undertaken jointly by CALIS and Peking University Library,this paper discusses the targeted object,content,the structure and the attributes of CALIS evaluation indicator system for digital resources.We also offer a detailed guideline for professional practice in terms of using this particular indicator system to evaluate the viability and the collection strength of a given digital library.

  10. Mental Training with Youth Sport Teams: Developmental Considerations & Best Practice Recommendations

    OpenAIRE

    Visek, Amanda J.; Harris, Brandonn; Blom, Lindsey C.

    2013-01-01

    Working with youth athletes requires knowledge of the inherent variability in child and adolescent development that will impact the implementation of a mental training program. The purpose of this paper is to provide an overview of developmental considerations that should be noted when doing mental training, particularly for athletes participating in sport at mid-childhood, early adolescence, and mid-adolescence. Gender differences at these stages of development are also highlighted. Addition...

  11. Responses to perceived unethical practices in clinical neuropsychology: ethical and legal considerations.

    Science.gov (United States)

    Grote, C L; Lewin, J L; Sweet, J J; van Gorp, W G

    2000-02-01

    Neuropsychologists often review the work of colleagues who have performed a neuropsychological evaluation. At times, these reviews may cause one to believe that a colleague acted in an unethical manner. However, it is often unclear whether the situation warrants contacting the colleague or filing a complaint. This article provides examples of potential unethical practices in neuropsychology, and then reviews the relevant ethical principles and legal precedents concerning the obligations and possible risks of reporting perceived unethical practices of a colleague. The paper concludes with a series of recommendations and options as to when and how one should proceed in such situations. PMID:10855065

  12. Practical aspects of prostate MRI: hardware and software considerations, protocols, and patient preparation.

    Science.gov (United States)

    Starobinets, Olga; Korn, Natalie; Iqbal, Sonam; Noworolski, Susan M; Zagoria, Ronald; Kurhanewicz, John; Westphalen, Antonio C

    2016-05-01

    The use of multiparametric MRI scans for the evaluation of men with prostate cancer has increased dramatically and is likely to continue expanding as new developments come to practice. However, it has not yet gained the same level of acceptance of other imaging tests. Partly, this is because of the use of suboptimal protocols, lack of standardization, and inadequate patient preparation. In this manuscript, we describe several practical aspects of prostate MRI that may facilitate the implementation of new prostate imaging programs or the expansion of existing ones. PMID:27193785

  13. Practical Considerations When Supporting Transitions for Pupils with Speech, Language and Communication Needs

    Science.gov (United States)

    Perfitt, Ruth

    2013-01-01

    This article investigates the impact of transitions upon pupils aged 11-14 with speech, language and communication needs, including specific language impairment and autism. The aim is to identify stress factors, examine whether these affect any subgroups in particular and suggest practical strategies to support pupils through transitions. Stress…

  14. Ethical Considerations in a Three-Tiered Approach to School Discipline Policy and Practice

    Science.gov (United States)

    Mayworm, Ashley M.; Sharkey, Jill D.

    2014-01-01

    Research indicates that school discipline policies and practices have a significant influence on both student and school functioning. The purpose of this article is to uncover how the ethical standards guiding the field of school psychology inform school decisions about discipline in a three-tiered approach. Various discipline approaches,…

  15. Confronting the Ubiquity of Electronic Communication and Social Media: Ethical and Legal Considerations for Psychoeducational Practice

    Science.gov (United States)

    Demers, Joseph A.; Sullivan, Amanda L.

    2016-01-01

    Most U.S. children and adults use computers and the Internet on a daily basis. The pervasiveness of electronic communication in a variety of contexts, including home and school, raises ethical and legal concerns for school psychologists and those in related fields of practice, because of the risks to privacy and confidentiality, boundaries,…

  16. Practical considerations for integrating switch mode audio amplifiers and loudspeakers for a higher power efficiency

    DEFF Research Database (Denmark)

    Poulsen, Søren; Andersen, Michael Andreas E.

    2004-01-01

    An integration of electrodynamic loudspeakers and switch mode amplifiers has earlier been proposed in [1]. The work presented in this paper is related to the practical aspects of integration of switch mode audio amplifiers and electro dynamic loudspeakers, using the speaker’s voice coil as output...

  17. The Amtex DAMA Project: The Brookhaven contribution

    Energy Technology Data Exchange (ETDEWEB)

    Peskin, A.M.

    1995-01-01

    The Amtex Partnership organized in 1993 as a Technology Transfer Collaboration among members of the integrated textile industry, the DOE National Laboratories, a number of universities, and several research/education/technology transfer organizations (RETTs). Under the Amtex umbrella organization, a number of technology areas were defined and individual projects were launched addressing various aspects of improving the health and competitiveness of the American textile industry. The first and, to date, the largest of these has been the computer-based Demand Activated Manufacturing Architecture (DAMA) project. Brookhaven National Laboratory became involved in DAMA beginning in March of 1993 and remained an active participant through January of 1995. It was staffed almost exclusively with personnel of the Computing and Communications Division. This document summarizes the activities and accomplishments of the Brookhaven team in working with the larger collaboration. Detailed information about the Amtex Partnership, the DAMA Project, and specific BNL contributions are documented elsewhere.

  18. Database activities at Brookhaven National Laboratory

    International Nuclear Information System (INIS)

    Brookhaven National Laboratory is a multi-disciplinary lab in the DOE system of research laboratories. Database activities are correspondingly diverse within the restrictions imposed by the dominant relational database paradigm. The authors discuss related activities and tools used in RHIC and in the other major projects at BNL. The others are the Protein Data Bank being maintained by the Chemistry department, and a Geographical Information System (GIS)--a Superfund sponsored environmental monitoring project under development in the Office of Environmental Restoration

  19. The Brookhaven electron analogue, 1953--1957

    International Nuclear Information System (INIS)

    The following topics are discussed on the Brookhaven electron analogue: L.J. Haworth and E.L. VanHorn letters; Original G.K. Green outline for report; General description; Parameter list; Mechanical Assembly; Alignment; Degaussing; Vacuum System; Injection System; The pulsed inflector; RF System; Ferrite Cavity; Pick-up electrodes and preamplifiers; Radio Frequency power amplifier; Lens supply; Controls and Power; and RF acceleration summary

  20. BLIP. [Brookhaven Linac Isotope Producer (BLIP)

    Energy Technology Data Exchange (ETDEWEB)

    Stang, Jr, L G

    1976-01-01

    The operation of the Brookhaven Linac Isotope Producer (BLIP) is discussed. Topics covered include targets, target holders, linac specifications, beam transport, and current production performance. The use of the BLIP is confined exclusively to the development of radionuclides that are, or should be, of medical interest, and the facility is moving rapidly into a self-supporting state from the income of the products. (PMA)

  1. The Brookhaven electron analogue, 1953--1957

    Energy Technology Data Exchange (ETDEWEB)

    Plotkin, M.

    1991-12-18

    The following topics are discussed on the Brookhaven electron analogue: L.J. Haworth and E.L. VanHorn letters; Original G.K. Green outline for report; General description; Parameter list; Mechanical Assembly; Alignment; Degaussing; Vacuum System; Injection System; The pulsed inflector; RF System; Ferrite Cavity; Pick-up electrodes and preamplifiers; Radio Frequency power amplifier; Lens supply; Controls and Power; and RF acceleration summary.

  2. The Brookhaven National Laboratory Accelerator Test Facility

    International Nuclear Information System (INIS)

    The Brookhaven National Laboratory Accelerator Test Facility comprises a 50 MeV traveling wave electron linear accelerator utilizing a high gradient, photo-excited, raidofrequency electron gun as an injector and an experimental area for study of new acceleration methods or advanced radiation sources using free electron lasers. Early operation of the linear accelerator system including calculated and measured beam parameters are presented together with the experimental program for accelerator physics and free electron laser studies

  3. General practitioners' management of mental disorders: A rewarding practice with considerable obstacles

    Directory of Open Access Journals (Sweden)

    Fleury Marie-Josée

    2012-03-01

    Full Text Available Abstract Background Primary care improvement is the cornerstone of current reforms. Mental disorders (MDs are a leading cause of morbidity worldwide and widespread in industrialised countries. MDs are treated mainly in primary care by general practitioners (GPs, even though the latter ability to detect, diagnose, and treat patients with MDs is often considered unsatisfactory. This article examines GPs' management of MDs in an effort to acquire more information regarding means by which GPs deal with MD cases, impact of such cases on their practices, factors that enable or hinder MD management, and patient-management strategies. Methods This study employs a mixed-method approach with emphasis on qualitative investigation. Based on a previous survey of 398 GPs in Quebec, Canada, 60 GPs representing a variety of practice settings were selected for further study. A 10-minute-long questionnaire comprising 27 items was administered, and 70-minute-long interviews were conducted. Quantitative (SPSS and qualitative (NVivo analyses were performed. Results At least 20% of GP visits were MD-related. GPs were comfortable managing common MDs, but not serious MDs. GPs' based their treatment of MDs on pharmacotherapy, support therapy, and psycho-education. They used clinical intuition with few clinical tools, and closely followed their patients with MDs. Practice features (salary or hourly fees payment; psycho-social teams on-site; strong informal networks, and GPs' individual characteristics (continuing medical education; exposure and interest in MDs; traits like empathy favoured MD management. Collaboration with psychologists and psychiatrists was considered key to good MD management. Limited access to specialists, system fragmentation, and underdeveloped group practice and shared-care models were impediments. MD management was seen as burdensome because it required more time, flexibility, and emotional investment. Strategies exist to reduce the burden (one

  4. Initial Freudian theories and practices: considerations on discovery of the unconscious

    Directory of Open Access Journals (Sweden)

    Daniel Polimeni Maireno

    2014-06-01

    Full Text Available This article compares some theoretical postulates and some clinical practices of early moments of Freudian works, favoring production periods of Studies on Hysteria and the Interpretation of Dreams. Other works are cited in order to complement. The study highlights the role of concepts such as repression, resistance and transference before the emergence of the concept of the unconscious – without which all previous lose much of their senses; suggests that, rather than a Freud’s willful disposition in the formulation of concept of the unconscious, what we see is, instead, his reluctance to admit such a concept, which justifies its late appearance compared to the others. We conclude, finally, that such reluctance itself, conveys a valuable model to psychoanalysts about how theoretical and practical developments of psychoanalysis must happens.

  5. The practical considerations of dose constraints in diagnostic medical departments using ionizing radiation

    International Nuclear Information System (INIS)

    The term 'dose constraint' has been used in radiological protection since 1990. Its practical application has varied from country to country to the present day. The authors of this paper believe that it is an underestimated tool for the purpose of radiological protection. This study aims to estimate local dose constraints for workers in conventional nuclear medicine and radiology departments, on the basis of doses received in the last 3 to 4 years by different groups of workers. The levels of exposure to employees of the nuclear medicine department correspond well to levels in other countries, but for employees belonging to the radiology department, the levels are significantly lower. Unification of the practical application of dose constraints and legislation concerning their specific values would increase the relevance and effectiveness of these operational units. This is a playing field for radiation safety officers for the determination and widespread publication of local dose constraints in their particular medical departments. (authors)

  6. The laws, regulations, and industry practices that protect consumers who use electronic payment systems: policy considerations

    OpenAIRE

    Mark Furletti

    2005-01-01

    This is the third in a series of three papers that examines the laws, regulations, and voluntary industry practices that may aid consumers who contest an electronic transaction because of error, fraud, or merchant dispute. The first two papers describe the complex web of protections available to users of four popular electronic payment mechanisms: credit cards, debit cards, prepaid cards, and ACH e-checks. This third paper considers how protections related to fraud, error, and disputes affect...

  7. General Considerations on Leadership in the Hospitality Industry. Conceptual Analysis and Practical Studies

    OpenAIRE

    Andreia ISPAS

    2010-01-01

    Leadership in the hospitality industry is still an open research field especially in describing the effects of leadership style on hotel employees. The purpose of the paper is to present and analyze the following concepts: leadership and leadership style, hospitality industry; the practical aspects of leadership in the hospitality industry and to identify relevant studies regarding the importance of leadership styles applied in this industry. The research methodology consists of analyzing the...

  8. Outcome measures for routine use in dementia services: some practical considerations.

    OpenAIRE

    Higginson, I J; Jefferys, P. M.; Hodgson, C S

    1997-01-01

    OBJECTIVES: To work with specialist community teams to assess the practicality and acceptability of identified outcome measures for routine use in dementia services. SETTING: Seven specialist dementia services: four multidisciplinary teams, a specialist service for carers, a community psychiatric nurse team, and a day hospital. SUBJECTS: 20 members of staff from the specialist dementia services including psychiatry, community psychiatric nursing, social work, occupational therapy, Admiral nur...

  9. THE CRIMINAL OFFENCE OF MONEY LAUNDERING – A SERIES OF THEORETICAL AND PRACTICAL CONSIDERATIONS

    Directory of Open Access Journals (Sweden)

    Constantin NEDELCU

    2016-05-01

    Full Text Available The paper at hand addresses the extremely complex and sensitive matter relating to one of the most controversial offences in the criminal laws of Romania – in particular, the criminal offence of money laundering. This paper bears both theoretical and practical interest, in that it points out specific instances of court case-law which were given different constructions by various judiciary authorities.

  10. Recruitment and retention of young women into nutrition research studies: practical considerations

    OpenAIRE

    Leonard, Alecia; Hutchesson, Melinda; Patterson, Amanda; Chalmers, Kerry; Collins, Clare

    2014-01-01

    Background Successful recruitment and retention of participants into research studies is critical for optimising internal and external validity. Research into diet and lifestyle of young women is important due to the physiological transitions experienced at this life stage. This paper aims to evaluate data related to recruitment and retention across three research studies with young women, and present practical advice related to recruiting and retaining young women in order to optimise study ...

  11. Open lung high frequency ventilation in preterm infants with respiratory distress syndrome: practical considerations and recommendations

    OpenAIRE

    De Jaegere, A.P.M.C.

    2012-01-01

    In premature infants ventilated because of RDS the favorable effect of HFV OLV compared to conventional mechanical ventilation on the incidence of BPD remains a matter of debate. An important lack in published human studies is the clinical practice surrounding the thorough application of OLV with HFV from the acute stage of RDS through the weaning process until extubation. Studies in this thesis demonstrate that applying a "full package" OLV from start to finish in respiratory failure with hi...

  12. Decision-theoretic consideration of robust perceptual hashing: link to practical algorithms

    OpenAIRE

    Koval, Oleksiy; Voloshynovskyy, Svyatoslav; Beekhof, Fokko Pieter; Pun, Thierry

    2007-01-01

    In this paper we propose to consider the problem of robust perceptual hashing of multimedia data as composite hypothesis testing. Such a problem formulation is justified by prior ambiguity about source statistics and channel parameters that is usually the case in multiple practical scenarios. An asymptotically universal test approaching the performance of the classical maximum likelihood test performed under the exact knowledge of the mentioned statistics is proposed under the specific constr...

  13. Measuring Provider Attitudes Toward Evidence-Based Practice: Consideration of Organizational Context and Individual Differences

    OpenAIRE

    Aarons, Gregory A

    2005-01-01

    Mental health provider attitudes toward adoption of innovation in general, and toward evidence-based practice (EBP) in particular, are important in considering how best to disseminate and implement EBPs. This article first explores the role of attitudes in acceptance of innovation and proposes a model of organizational and individual factors that may affect or be affected by attitudes toward adoption of EBP. Next, a recently developed measure of mental health provider attitudes toward adoptio...

  14. Involving older people in research: practical considerations when using the authenticity criteria in constructivist inquiry

    OpenAIRE

    Brown Wilson, Christine; Clissett, Philip

    2011-01-01

    Aim The purpose of this paper is to identify practical suggestions that could enable other researchers to consider how quality may be evidenced using constructivist principles including the perspectives of older people and their caregivers. Background Constructivism suggests that reality is part of a social construction, which holds different meanings for each person, in which people are active agents, making autonomous decisions. This approach to research has been identified as sui...

  15. Involving older people in research: practical considerations when using the authenticity criteria in constructivist inquiry

    OpenAIRE

    Wilson, Christine Brown; Clissett, Philip

    2011-01-01

    Aim The purpose of this paper is to identify practical suggestions that could enable other researchers to consider how quality may be evidenced using constructivist principles including the perspectives of older people and their caregivers. Background Constructivism suggests that reality is part of a social construction, which holds different meanings for each person, in which people are active agents, making autonomous decisions. This approach to research has been identified as suitable for ...

  16. Eye dosimetry in interventional radiology and cardiology: current challenges and practical considerations.

    Science.gov (United States)

    Ciraj-Bjelac, O; Rehani, M M

    2014-12-01

    Interventional radiology and cardiology are areas with high potential for risk to eye lens. Accurate assessment of eye dose is one of the most important aspects of correlating doses with observed lens opacities among workers in interventional suites and ascertaining compliance with regulatory limits. The purpose of this paper is to review current approaches and opportunities in eye dosimetry and assess challenges in particular in accuracy and practicality. The possible approaches include practical dosimetry using passive dosemeters or active dosemeters with obvious advantage of active dosimetry. When neither of these is available, other approaches are based on either retrospective dose assessment using scatter radiation dose levels or correlations between patient dose indices and eye doses to the operators. In spite of all uncertainties and variations, estimation of eye dose from patient dose can be accepted as a compromise. Future challenges include development of practical methods for regular monitoring of individual eye doses and development of better techniques to estimate eye dose from measurements at some reference points. PMID:24262928

  17. Eye dosimetry in interventional radiology and cardiology: current challenges and practical considerations

    International Nuclear Information System (INIS)

    Interventional radiology and cardiology are areas with high potential for risk to eye lens. Accurate assessment of eye dose is one of the most important aspects of correlating doses with observed lens opacities among workers in interventional suites and ascertaining compliance with regulatory limits. The purpose of this paper is to review current approaches and opportunities in eye dosimetry and assess challenges in particular in accuracy and practicality. The possible approaches include practical dosimetry using passive dosemeters or active dosemeters with obvious advantage of active dosimetry. When neither of these is available, other approaches are based on either retrospective dose assessment using scatter radiation dose levels or correlations between patient dose indices and eye doses to the operators. In spite of all uncertainties and variations, estimation of eye dose from patient dose can be accepted as a compromise. Future challenges include development of practical methods for regular monitoring of individual eye doses and development of better techniques to estimate eye dose from measurements at some reference points. (authors)

  18. Practical guidance and considerations for transitioning patients from oxcarbazepine or carbamazepine to eslicarbazepine acetate--Expert opinion.

    Science.gov (United States)

    Peltola, Jukka; Holtkamp, Martin; Rocamora, Rodrigo; Ryvlin, Philippe; Sieradzan, Kasia; Villanueva, Vicente

    2015-09-01

    There is currently a lack of guidance on methodology and special considerations for transitioning patients from oxcarbazepine (OXC) or carbamazepine (CBZ) to eslicarbazepine acetate (ESL), if deemed clinically necessary. An advisory panel of epilepsy experts was convened to share their experience on the use of adjunctive ESL in clinical practice and to provide practical recommendations to help address this gap. When changing over from OXC to ESL, an OXC:ESL dose ratio of 1:1 should be employed to calculate the ESL target dose, and the changeover can take place overnight. No changes to comedication are required. Since CBZ has a different mechanism of action to ESL and is a stronger inducer of cytochrome P450 (CYP) enzymes, the transitioning of patients from CBZ to ESL requires careful consideration on a patient-by-patient basis. In general, a CBZ:ESL dose ratio of 1:1.3 should be employed to calculate the ESL target dose, and patients should be transitioned over a minimum period of 1-2weeks. Special considerations include adjustment of titration schedule and target dose in elderly patients and those with hepatic or renal impairment and potential adjustment of comedications metabolized by CYP enzymes. In summary, due to structural distinctions between ESL, OXC, and CBZ, which affect mechanism of action and tolerability, there are clinical situations in which it may be appropriate to consider transitioning patients from OXC or CBZ to ESL. Changing patients over from OXC to ESL is generally more straightforward than transitioning patients from CBZ to ESL, which requires careful consideration. PMID:26114438

  19. The consideration of ecological safety in judicial practice-also on the ecological safety legislation

    Institute of Scientific and Technical Information of China (English)

    L(U) Zhongmei

    2006-01-01

    Ecological safety has been one of the hot issues of environmental law in recent years.The maintenance of ecological safety has become one of the legislative principles,as exemplified by the revision of the Law of Sand Prevention and Sand.Management and the Law against Solid Waste Environmental Pollution,and the relevant rules that will be established.However actual cases will still happen,whether the legislators have made the statutory law or not.While scholars and legislators are debating,the judges have to handle cases and render judgments.Through the analysis of a case,this article will discuss the feasibility for judges to make ecological safety considerations in the judicial process by applying the principle of good faith and will also discuss the legislative issues related to ecological safety.

  20. Ethical challenges in social media engagement and research: considerations for code of engagement practices.

    Science.gov (United States)

    Gehner, Monika; Oughton, Deborah

    2016-06-01

    Social media have great potential for effectively communicating about public health risks so people make healthier and safer choices. If used appropriately, social media can strengthen trust between the public and the institution. If used inappropriately, it may also create distrust. This note addresses some of the ethical challenges in using social media for communication and research. It reflects on opportunities in social media risk communication based on experience from the World Health Organization (WHO) and suggests a code of engagement be included in corporate social media policies that contain guidance as to what conduct is or is not appropriate with a view to maintaining public trust in the institution. The note concludes with considerations about the ethical use of social media in research, which is particularly relevant for entities communicating about ionizing radiation, including during emergency situations. PMID:27270048

  1. Proton therapy for head and neck cancer: Rationale, potential indications, practical considerations, and current clinical evidence

    International Nuclear Information System (INIS)

    There is a strong rationale for potential benefits from proton therapy (PT) for selected cancers of the head and neck because of the opportunity to improve the therapeutic ratio by improving radiation dose distributions and because of the significant differences in radiation dose distribution achievable with x-ray-based radiation therapy (RT) and PT. Comparisons of dose distributions between x-ray-based and PT plans in selected cases show specific benefits in dose distribution likely to translate into improved clinical outcomes. However, the use of PT in head and neck cancers requires special considerations in the simulation and treatment planning process, and currently available PT technology may not permit realization of the maximum potential benefits of PT. To date, few clinical data are available, but early clinical experiences in sinonasal tumors in particular suggest significant improvements in both disease control and radiation-related toxicity

  2. Landmarks in particle physics at Brookhaven National Laboratory: Brookhaven Lecture Series, Number 238

    International Nuclear Information System (INIS)

    Robert Adair's lecture on Landmarks in Particle Physics at Brookhaven National Laboratory (BNL) is a commemoration of the 40th Anniversary of Brookhaven National Laboratory. Adair describes ten researches in elementary particle physics at Brookhaven that had a revolutionary impact on the understanding of elementary particles. Two of the discoveries were made in 1952 and 1956 at the Cosmotron, BNL's first proton accelerator. Four were made in 1962 and 1964 at the Alternating Gradient Synchrotron, the Cosmotron's replacement. Two other discoveries in 1954 and 1956 were theoretical, and strong focusing (1952) is the only technical discovery. One discovery (1958) happened in an old barrack. Four of the discoveries were awarded the Nobel prize in Physics. Adair believes that all of the discoveries are worthy of the Nobel prize. 14 figs

  3. The practices of do-it-yourself brain stimulation: implications for ethical considerations and regulatory proposals.

    Science.gov (United States)

    Wexler, Anna

    2016-04-01

    Scientists and neuroethicists have recently drawn attention to the ethical and regulatory issues surrounding the do-it-yourself (DIY) brain stimulation community, which comprises individuals stimulating their own brains with transcranial direct current stimulation (tDCS) for self-improvement. However, to date, existing regulatory proposals and ethical discussions have been put forth without engaging those involved in the DIY tDCS community or attempting to understand the nature of their practices. I argue that to better contend with the growing ethical and safety concerns surrounding DIY tDCS, we need to understand the practices of the community. This study presents the results of a preliminary inquiry into the DIY tDCS community, with a focus on knowledge that is formed, shared and appropriated within it. I show that when making or acquiring a device, DIYers (as some members call themselves) produce a body of knowledge that is completely separate from that of the scientific community, and share it via online forums, blogs, videos and personal communications. However, when applying tDCS, DIYers draw heavily on existing scientific knowledge, posting links to academic journal articles and scientific resources and adopting the standardised electrode placement system used by scientists. Some DIYers co-opt scientific knowledge and modify it by creating their own manuals and guides based on published papers. Finally, I explore how DIYers cope with the methodological limitations inherent in self-experimentation. I conclude by discussing how a deeper understanding of the practices of DIY tDCS has important regulatory and ethical implications. PMID:26324456

  4. Patient attributes warranting consideration in clinical practice guidelines, health workforce planning and policy

    Directory of Open Access Journals (Sweden)

    Segal Leonie

    2011-09-01

    Full Text Available Abstract Background In order for clinical practice guidelines (CPGs to meet their broad objective of enhancing the quality of care and supporting improved patient outcomes, they must address the needs of diverse patient populations. We set out to explore the patient attributes that are likely to demand a unique approach to the management of chronic disease, and which are crucial if evidence or services planning is to reflect clinic populations. These were incorporated into a new conceptual framework; using diabetes mellitus as an exemplar. Methods The patient attributes that informed the framework were identified from CPGs, the diabetes literature, an expert academic panel, and two cross-disciplinary panels; and agreed upon using a modified nominal group technique. Results Full consensus was reached on twenty-four attributes. These factors fell into one of three themes: (1 type/stage of disease, (2 morbid events, and (3 factors impacting on capacity to self-care. These three themes were incorporated in a convenient way in the workforce evidence-based (WEB model. Conclusions While biomedical factors are frequently recognised in published clinical practice guidelines, little attention is given to attributes influencing a person's capacity to self-care. Paying explicit attention to predictable threats to effective self-care in clinical practice guidelines, by drawing on the WEB model, may assist in refinements that would address observed disparities in health outcomes across socio-economic groups. The WEB model also provides a framework to inform clinical training, and health services and workforce planning and research; including the assessment of healthcare needs, and the allocation of healthcare resources.

  5. Allelic drop-out probabilities estimated by logistic regression--Further considerations and practical implementation

    DEFF Research Database (Denmark)

    Tvedebrink, Torben; Eriksen, Poul Svante; Asplund, Maria;

    2012-01-01

    We discuss the model for estimating drop-out probabilities presented by Tvedebrink et al. [7] and the concerns, that have been raised. The criticism of the model has demonstrated that the model is not perfect. However, the model is very useful for advanced forensic genetic work, where allelic drop......-out is occurring. With this discussion, we hope to improve the drop-out model, so that it can be used for practical forensic genetics and stimulate further discussions. We discuss how to estimate drop-out probabilities when using a varying number of PCR cycles and other experimental conditions....

  6. Some considerations on how to solve the Sherman equation in practice

    International Nuclear Information System (INIS)

    This article discusses the true nature of the problems involved in the solution of the Sherman equation in practice and demonstrates that the Fundamental Algorithm (FA) method, in association with its efficient calibration procedure, proposed by Rousseau in 1982, is still a valid solution. However, the author recognizes that the FA method is not the only valid one, and others have also been proposed. This article does not propose a new analytical method, but describes the three essential characteristics that any valid solution must have. It also suggests some mathematical search avenues to examine for discovering any new valid solution in the future

  7. Practical considerations on the use of rituximab in autoimmune neurological disorders

    Science.gov (United States)

    Kosmidis, Mixalis L.; Dalakas, Marinos C.

    2010-01-01

    Rituximab (Mabthera, Rituxan) is a chimeric human/murine monoclonal antibody against CD-20 surface antigen expressed on B-cells. Rituximab, by causing B-cell depletion, appears to be effective in several autoimmune disorders; it has been approved for rheumatoid arthritis and is a promising new agent in the treatment of several autoimmune neurological disorders. A controlled study in patients with relapsing remitting multiple sclerosis has shown that rituximab significantly reduces the number of new MRI lesions and improves clinical outcome; it also showed some promise in a subset of patients with primary progressive MS. The drug is also effective in a number of patients with Devic’s disease, myasthenia gravis, autoimmune neuropathies, and inflammatory myopathies. The apparent effectiveness of rituximab has moved B-cells into the center stage of clinical and laboratory investigation of autoimmune neurological disorders. We review the evidence-based effectiveness of rituximab in neurological disorders based on controlled trials and anecdotal reports, including our own experience, and address the immunobiology of B-cells in autoimmune central nervous system (CNS) and peripheral nervous system (PNS) disorders. In addition, we provide practical guidelines on how best to use this drug in clinical practice and highlight its potential toxicity. PMID:21179602

  8. Risk management in clinical practice. Part 5. Ethical considerations for dental enhancement procedures.

    Science.gov (United States)

    Ahmad, I

    2010-09-11

    After the demise of the Industrial Age, we currently live in an 'Information Age' fuelled mainly by the Internet, with an ever-increasing medically and dentally literate population. The media has played its role by reporting scientific advances, as well as securitising medical and dental practices. Reality television such as 'Extreme makeovers' has also raised public awareness of body enhancements, with a greater number of people seeking such procedures. To satiate this growing demand, the dental industry has flourished by introducing novel cosmetic products such as bleaching kits, tooth coloured filling materials and a variety of dental ceramics. In addition, one only has to browse through a dental journal to notice innumerable courses and lectures on techniques for providing cosmetic dentistry. The incessant public interest, combined with unrelenting marketing by companies is gradually shifting the balance of dental care from a healing to an enhancement profession. The purpose of this article is to endeavour to answer questions such as, What is aesthetic or cosmetic dentistry? Why do patients seek cosmetic dentistry? Are enhancement procedures a part of dental practice? What, if any, ethical guidelines and constraints apply to elective enhancement procedures? What is the role of the dentist in providing or encouraging this type of 'therapy'? What treatment modalities are available for aesthetic dental treatment? PMID:20829856

  9. Memory Interventions in the Criminal Justice System: Some Practical Ethical Considerations.

    Science.gov (United States)

    Cabrera, Laura Y; Elger, Bernice S

    2016-03-01

    In recent years, discussion around memory modification interventions has gained attention. However, discussion around the use of memory interventions in the criminal justice system has been mostly absent. In this paper we start by highlighting the importance memory has for human well-being and personal identity, as well as its role within the criminal forensic setting; in particular, for claiming and accepting legal responsibility, for moral learning, and for retribution. We provide examples of memory interventions that are currently available for medical purposes, but that in the future could be used in the forensic setting to modify criminal offenders' memories. In this section we contrast the cases of (1) dampening and (2) enhancing memories of criminal offenders. We then present from a pragmatic approach some pressing ethical issues associated with these types of memory interventions. The paper ends up highlighting how these pragmatic considerations can help establish ethically justified criteria regarding the possibility of interventions aimed at modifying criminal offenders' memories. PMID:26715046

  10. Practical considerations in choosing a factor VIII prophylaxis regimen: Role of clinical phenotype and trough levels.

    Science.gov (United States)

    Ljung, Rolf; Fischer, Kathelijn; Carcao, Manuel; Santagostino, Elena; Manco-Johnson, Marilyn J; Mathew, Prasad

    2016-05-01

    Current therapy for haemophilia A is guided by severity of the disease, which in turn is best reflected in patients' endogenous factor VIII activity levels. For patients with severe haemophilia (particularly children), prophylaxis with continuous routine factor replacement has become standard of care in developed countries and is gradually becoming the standard of care in developing countries. The question arises then: what is an appropriate prophylaxis regimen to prevent bleeding events and arthropathy, while also maximizing patient quality of life and taking into consideration the costs of prophylaxis? Should all patients be treated with one standard, fixed prophylaxis regimen, or should prophylaxis be individualised for each patient? If so, what factors need to be considered in choosing the appropriate dose and frequency of factor administration? If prophylaxis is tailored to the individual patient, then patient-related factors (bleeding phenotype, activity profiles, age, joint status) and product-specific factors (half-life of the replacement factor in the individual patient) will determine the choice of regimen, whether it be a fixed-regimen prophylaxis or prophylaxis that is tailored to patient activity and bleeding risk. Regardless of the choice of prophylaxis regimen, for any regimen to be effective, adherence to therapy is key to optimising outcomes. PMID:26791493

  11. Italian regulatory perspective on safety culture: Current practice and considerations for next generation reactors

    International Nuclear Information System (INIS)

    It is a common understanding that a regulatory body has two different commitments with respect to ''safety culture''. The first commitment concerns the implementation of the different elements that characterize the ''safety culture'' inside its own organization. It could seem obvious that an effective safety culture naturally pervades the regulatory body staff in the accomplishment of its peculiar duties, but it is probably less obvious that many actions have to be undertaken to bring that attitudes at the requested level of excellence. The second commitment pertains the different actions that are put in place in the discharge of its safety control duties and responsibilities and that are aimed at the promotion of a ''safety culture approach'' inside the general designer, the architect engineer, the components supplier and, above all, the utility, being well aware of the fact that NPPs operational safety strictly depends on those who designed, constructed, commissioned and operated them. This paper briefly discusses some examples connected to the past experience within the Italian regulatory body (DISP) in the accomplishment of its commitment regarding safety culture. It also provides a glance into the future, by reporting some considerations on the potential modifications that can be envisaged in the way to look at some elements of the ''safety culture'' on the basis of the next generation reactors design criteria. (author)

  12. Treatment of Chronic Inflammatory Demyelinating Polyneuropathy: From Molecular Bases to Practical Considerations

    Directory of Open Access Journals (Sweden)

    Paolo Ripellino

    2014-01-01

    Full Text Available Chronic inflammatory demyelinating polyneuropathy (CIDP is an autoimmune disease of the peripheral nervous system, in which both cellular and humoral immune responses are involved. The disease is clinically heterogeneous with some patients displaying pure motor form and others also showing a variable degree of sensory dysfunction; disease evolution may also differ from patient to patient, since monophasic, progressive, and relapsing forms are reported. Underlying such clinical variability there is probably a broad spectrum of molecular dysfunctions that are and will be the target of therapeutic strategies. In this review we first explore the biological bases of current treatments and subsequently we focus on the practical management that must also take into account pharmacoeconomic issues.

  13. Creating Safety in Primary Care Practice with Electronic Medical Records Requires the Consideration of System Dynamics

    Directory of Open Access Journals (Sweden)

    Timothy R. McEwen

    2011-01-01

    Full Text Available Improvement in quality and safety in health care often depends on eliminating errors. Using examples from our research on the medical testing processes in primary care medical practices, we argue that designing safer systems requires moving beyond frameworks that focus exclusively on error elimination to consider the broader system dynamics including information loops that can be critical to the overall stability of the system. We focus on describing the nature of information coupling in relation to the constructs of essential friction, autonomation, and ecological interface design and how these can lead to more resilient systems. With the recent push in the United States to move towards electronic medical records (EMR, we conclude with suggestions for improving EMR systems based on these concepts.

  14. On Displacement Height, from Classical to Practical Formulation: Stress, Turbulent Transport and Vorticity Considerations

    DEFF Research Database (Denmark)

    Sogachev, Andrey; Kelly, Mark C.

    2016-01-01

    previous stress-based formulations for displacement height can be seen as simplified cases of a more general definition including turbulent transport. Further, we also give a simplified and practical form for d that is in agreement with the general approach, exploiting the concept of vortex thickness scale...... from mixing-layer theory.We assess the new and previous displacement height formulations by using flow statistics derived from the atmospheric boundary-layer Reynolds-averaged Navier–Stokes model SCADIS as well as from wind-tunnel observations, for different vegetation types and flow regimes in neutral......, accounting for the combined effects of turbulent transport and shear production. The Coriolis force also plays a role, introducing wind-speed dependence into the behaviour of the roughness sublayer; this affects the turbulent transport, shear production, stress, and wind speed, as well as the displacement...

  15. Opioid therapy for chronic low back pain: prescribing considerations for advanced practice registered nurses.

    Science.gov (United States)

    Lall, Maureen Patricia

    2014-12-01

    Chronic low back pain is a common, disabling, and costly condition, and advanced practice registered nurses (APRNs) must carefully evaluate patients before considering long-term opioid therapy as a management strategy. APRNs should refer patients suspected of having a serious condition, or identifiable etiology, for specialist evaluation, as many patients improve with physical therapy, interventional pain management procedures, or surgical intervention. For patients unresponsive to nonopioid treatment, APRNs with an understanding of opioids, and the experience to assess and manage the risks of opioid misuse, abuse, and diversion, may consider long-term opioid therapy as part of a multimodal management plan. Such prescribing necessitates careful patient selection; informed consent; prudent opioid dosing and titration; and monitoring for response to treatment, adverse effects, and aberrant drug-taking behavior. Treatment and regulatory guidelines can assist APRNs in providing safe and effective care to patients with chronic low back pain. PMID:25365050

  16. Field theory approaches to new media practices: An introduction and some theoretical considerations

    DEFF Research Database (Denmark)

    Hartley, Jannie Møller; Willig, Ida; Waltorp, Karen

    2015-01-01

    In this article introducing the theme of the special issue we argue that studies of new media practices might benefit from especially Pierre Bourdieu’s research on cultural production. We introduce some of the literature, which deals with the use of digital media, and which have taken steps to...... develop field theory in this context. Secondly, we present the four thematic articles in this issue and the articles outside the theme, which includes two translations of classic texts within communication and media research. This introduction article concludes by encouraging media scholars to embark on...... more studies within a field theory framework, as the ability of the comprehensive theoretical work and the ideas of a reflexive sociology is able to trigger the good questions, more than it claims to offer a complete and self-sufficient sociology of media and inherent here also new media....

  17. Quagmires for clinical psychology and executive coaching? Ethical considerations and practice challenges.

    Science.gov (United States)

    Gebhardt, Judith Ann

    2016-04-01

    As the coaching field burgeons, both the mental health and coaching professionals, and their respective professions, face a myriad of potential quagmires, especially if the unique challenges encountered are ignored. After a short introduction and presentation on ethics and morals related to executive coaching and clinical therapy, a discussion follows on the lengthy and intimate relationship between executive coaching and psychology. Next are definitions and comparisons and 6 areas that are potential quagmires. This includes roles, skill sets/core competencies, education/training, licensing/credentialing-certification, governing bodies and confidentiality, and fees/reimbursement. Each section includes a discussion and several questions to highlight potentially problematic areas, practice challenges, and/or ethical issues, followed with brief responses. This paper concludes with the inquiry, "Where do we go from here?" PMID:27042883

  18. On Displacement Height, from Classical to Practical Formulation: Stress, Turbulent Transport and Vorticity Considerations

    Science.gov (United States)

    Sogachev, Andrey; Kelly, Mark

    2016-03-01

    Displacement height ( d) is an important parameter in the simple modelling of wind speed and vertical fluxes above vegetative canopies, such as forests. Here we show that, aside from implicit definition through a (displaced) logarithmic profile, accepted formulations for d do not consistently predict flow properties above a forest. Turbulent transport can affect the displacement height, and is an integral part of what is called the roughness sublayer. We develop a more general approach for estimation of d, through production of turbulent kinetic energy and turbulent transport, and show how previous stress-based formulations for displacement height can be seen as simplified cases of a more general definition including turbulent transport. Further, we also give a simplified and practical form for d that is in agreement with the general approach, exploiting the concept of vortex thickness scale from mixing-layer theory. We assess the new and previous displacement height formulations by using flow statistics derived from the atmospheric boundary-layer Reynolds-averaged Navier-Stokes model SCADIS as well as from wind-tunnel observations, for different vegetation types and flow regimes in neutral conditions. The new formulations tend to produce smaller d than stress-based forms, falling closer to the classic logarithmically-defined displacement height. The new, more generally defined, displacement height appears to be more compatible with profiles of components of the turbulent kinetic energy budget, accounting for the combined effects of turbulent transport and shear production. The Coriolis force also plays a role, introducing wind-speed dependence into the behaviour of the roughness sublayer; this affects the turbulent transport, shear production, stress, and wind speed, as well as the displacement height, depending on the character of the forest. We further show how our practical (`mixing-layer') form for d matches the new turbulence-based relation, as well as

  19. Brookhaven National Laboratory site environmental report for calendar year 1994

    Energy Technology Data Exchange (ETDEWEB)

    Naidu, J.R.; Royce, B.A. [eds.

    1995-05-01

    This report documents the results of the Environmental Monitoring Program at Brookhaven National Laboratory and presents summary information about environmental compliance for 1994. To evaluate the effect of Brookhaven National Laboratory`s operations on the local environment, measurements of direct radiation, and a variety of radionuclides and chemical compounds in ambient air, soil, sewage effluent, surface water, groundwater, fauna and vegetation were made at the Brookhaven National Laboratory site and at sites adjacent to the Laboratory.

  20. Brookhaven National Laboratory site environmental report for calendar year 1994

    International Nuclear Information System (INIS)

    This report documents the results of the Environmental Monitoring Program at Brookhaven National Laboratory and presents summary information about environmental compliance for 1994. To evaluate the effect of Brookhaven National Laboratory's operations on the local environment, measurements of direct radiation, and a variety of radionuclides and chemical compounds in ambient air, soil, sewage effluent, surface water, groundwater, fauna and vegetation were made at the Brookhaven National Laboratory site and at sites adjacent to the Laboratory

  1. Body diffusion kurtosis imaging: Basic principles, applications, and considerations for clinical practice.

    Science.gov (United States)

    Rosenkrantz, Andrew B; Padhani, Anwar R; Chenevert, Thomas L; Koh, Dow-Mu; De Keyzer, Frederik; Taouli, Bachir; Le Bihan, Denis

    2015-11-01

    Technologic advances enable performance of diffusion-weighted imaging (DWI) at ultrahigh b-values, where standard monoexponential model analysis may not apply. Rather, non-Gaussian water diffusion properties emerge, which in cellular tissues are, in part, influenced by the intracellular environment that is not well evaluated by conventional DWI. The novel technique, diffusion kurtosis imaging (DKI), enables characterization of non-Gaussian water diffusion behavior. More advanced mathematical curve fitting of the signal intensity decay curve using the DKI model provides an additional parameter Kapp that presumably reflects heterogeneity and irregularity of cellular microstructure, as well as the amount of interfaces within cellular tissues. Although largely applied for neural applications over the past decade, a small number of studies have recently explored DKI outside the brain. The most investigated organ is the prostate, with preliminary studies suggesting improved tumor detection and grading using DKI. Although still largely in the research phase, DKI is being explored in wider clinical settings. When assessing extracranial applications of DKI, careful attention to details with which body radiologists may currently be unfamiliar is important to ensure reliable results. Accordingly, a robust understanding of DKI is necessary for radiologists to better understand the meaning of DKI-derived metrics in the context of different tumors and how these metrics vary between tumor types and in response to treatment. In this review, we outline DKI principles, propose biostructural basis for observations, provide a comparison with standard monoexponential fitting and the apparent diffusion coefficient, report on extracranial clinical investigations to date, and recommend technical considerations for implementation in body imaging. PMID:26119267

  2. Consideration of the future in the WIPP regulations: Policy and practice

    International Nuclear Information System (INIS)

    The US Environmental Protection Agency (USEPA) published final regulations for the disposal of transuranic and certain other radioactive waste in 1993. These regulations contain standards that limit the amount of specific radionuclides that may be released from a disposal site over 10,000 years. The USEPA was directed by the United States Congress to develop criteria based on the general disposal regulations specifically for the Waste Isolation Pilot Plant (WIPP), a disposal site in New Mexico that is owned and operated by the U.S. Department of Energy (USDOE). EPA published the WIPP compliance criteria in 1996. Because transuranic waste will remain radioactive for many thousands of years, any prediction of the WIPP's performance will involve a significant amount of uncertainty regarding the factors that could affect containment. In an effort to constrain potentially endless speculation about future events, the USEPA specified in the WIPP compliance criteria the manner in which the USDOE must consider important events and processes that may occur at the WIPP site. This paper identifies and briefly explains the basis for USEPA's assumptions governing consideration of future events. The paper then reviews some significant issues that arose during USEPA's rulemaking for the final WIPP certification, and explains the effect these issues had on USEPA's decision making. Performance criteria for a disposal site inevitably must make assumptions about the future if the results of the performance assessment are to be meaningful. When forming assumptions, the regulatory agency must balance what is known about present conditions against what may happen despite our best predictions. Because assumptions about the future are likely to be controversial, they must be based as much as possible on concrete evidence. A strong factual foundation for assumptions, as well as an overall conservative approach that maximises negative consequences, can help to alleviate controversy and

  3. Finite-size scaling in silver nanowire films: design considerations for practical devices

    Science.gov (United States)

    Large, Matthew J.; Cann, Maria; Ogilvie, Sean P.; King, Alice A. K.; Jurewicz, Izabela; Dalton, Alan B.

    2016-07-01

    We report the first application of finite-size scaling theory to nanostructured percolating networks, using silver nanowire (AgNW) films as a model system for experiment and simulation. AgNWs have been shown to be a prime candidate for replacing Indium Tin Oxide (ITO) in applications such as capacitive touch sensing. While their performance as large area films is well-studied, the production of working devices involves patterning of the films to produce isolated electrode structures, which exhibit finite-size scaling when these features are sufficiently small. We demonstrate a generalised method for understanding this behaviour in practical rod percolation systems, such as AgNW films, and study the effect of systematic variation of the length distribution of the percolating material. We derive a design rule for the minimum viable feature size in a device pattern, relating it to parameters which can be derived from a transmittance-sheet resistance data series for the material in question. This understanding has direct implications for the industrial adoption of silver nanowire electrodes in applications where small features are required including single-layer capacitive touch sensors, LCD and OLED display panels.We report the first application of finite-size scaling theory to nanostructured percolating networks, using silver nanowire (AgNW) films as a model system for experiment and simulation. AgNWs have been shown to be a prime candidate for replacing Indium Tin Oxide (ITO) in applications such as capacitive touch sensing. While their performance as large area films is well-studied, the production of working devices involves patterning of the films to produce isolated electrode structures, which exhibit finite-size scaling when these features are sufficiently small. We demonstrate a generalised method for understanding this behaviour in practical rod percolation systems, such as AgNW films, and study the effect of systematic variation of the length distribution of

  4. Brookhaven highlights, October 1, 1989--September 30, 1990

    Energy Technology Data Exchange (ETDEWEB)

    Rowe, M.S.; Cohen, A.; Greenberg, D.; Seubert, L.; Kuper, J.B.H. (eds.)

    1990-01-01

    This report discusses research being conducted at Brookhaven National Laboratory. Highlights from all the department are illustrated. The main topics are on accelerator development and applications. (LSP)

  5. Practical Considerations for Determination of Glass Transition Temperature of a Maximally Freeze Concentrated Solution.

    Science.gov (United States)

    Pansare, Swapnil K; Patel, Sajal Manubhai

    2016-08-01

    Glass transition temperature is a unique thermal characteristic of amorphous systems and is associated with changes in physical properties such as heat capacity, viscosity, electrical resistance, and molecular mobility. Glass transition temperature for amorphous solids is referred as (T g), whereas for maximally freeze concentrated solution, the notation is (T g'). This article is focused on the factors affecting determination of T g' for application to lyophilization process design and frozen storage stability. Also, this review provides a perspective on use of various types of solutes in protein formulation and their effect on T g'. Although various analytical techniques are used for determination of T g' based on the changes in physical properties associated with glass transition, the differential scanning calorimetry (DSC) is the most commonly used technique. In this article, an overview of DSC technique is provided along with brief discussion on the alternate analytical techniques for T g' determination. Additionally, challenges associated with T g' determination, using DSC for protein formulations, are discussed. The purpose of this review is to provide a practical industry perspective on determination of T g' for protein formulations as it relates to design and development of lyophilization process and/or for frozen storage; however, a comprehensive review of glass transition temperature (T g, T g'), in general, is outside the scope of this work. PMID:27193003

  6. Fingermark age determinations: Legal considerations, review of the literature and practical propositions.

    Science.gov (United States)

    Girod, A; Ramotowski, R; Lambrechts, S; Misrielal, P; Aalders, M; Weyermann, C

    2016-05-01

    The question of the age of fingermarks is often raised in investigations and trials when suspects admit that they have left their fingermarks at a crime scene but allege that the contact occurred at a different time than the crime and for legal reasons. In the first part of this review article, examples from American appellate court cases will be used to demonstrate that there is a lack of consensus among American courts regarding the admissibility and weight of testimony from expert witnesses who provide opinions about the age of fingermarks. Of course, these issues are not only encountered in America but have also been reported elsewhere, for example in Europe. The disparity in the way fingermark dating cases were managed in these examples is probably due to the fact that no methodology has been validated and accepted by the forensic science community so far. The second part of this review article summarizes the studies reported on fingermark dating in the literature and highlights the fact that most proposed methodologies still suffer from limitations preventing their use in practice. Nevertheless, several approaches based on the evolution of aging parameters detected in fingermark residue over time appear to show promise for the fingermark dating field. Based on these approaches, the definition of a formal methodological framework for fingermark dating cases is proposed in order to produce relevant temporal information. This framework identifies which type of information could and should be obtained about fingermark aging and what developments are still required to scientifically address dating issues. PMID:27044033

  7. Incidental finding of tumor while investigating subarachnoid hemorrhage: ethical considerations and practical strategies.

    Science.gov (United States)

    Drazin, Doniel; Spitler, Kevin; Cekic, Milos; Patel, Ashish; Hanna, George; Shirzadi, Ali; Chu, Ray

    2013-09-01

    High-resolution neuroimaging modalities are used often in studies involving healthy volunteers. Subsequently, a significant increase in the incidental discovery of asymptomatic intracranial abnormalities raised the important ethical issues of when follow-up and treatment may be necessary. We examined the literature to establish a practical set of criteria for approaching incidental findings. Our objective is to develop an algorithm for when follow-up may be important and to provide recommendations that would increase the likelihood of follow-up. A systematic literature search was performed using the PubMed and MEDLINE databases to identify articles describing brain tumors and intracranial aneurysms. The treatment algorithm we present suggests that incidental intracranial masses suspicious for glioma should be biopsied or resected, while other masses are to be followed with serial imaging based on the expected growth pattern. Lack of follow-up can result in adverse outcomes that can be mitigated by using technology to facilitate communication and improve follow-up care. The importance of training physicians to be good communicators is also stressed. New technology including automated telephone systems, texting and email will improve access to patients and hopefully encourage compliance and follow-up. PMID:23065539

  8. Dancing through Cape Coast: ethical and practical considerations for health-related service-learning programs.

    Science.gov (United States)

    Saffran, Lise

    2013-09-01

    Short-term service-learning programs that focus on global health are expanding rapidly, spurred by students' desire to be of service in a world that has been made to seem small by new technology and universities' willingness to embrace the goal of educating global citizens. In this commentary, the author uses experiences from a recent trip she led to Ghana as a backdrop against which to explore some of the ethical and practical issues that arise when U.S. students work in health-related programs in developing countries. At minimum, the author argues, these programs should lead students to consider issues such as which basic services people are entitled to, regardless of where and in what circumstances they live, and how differences in access to social and economic resources contribute to health disparities on a global scale. She also suggests that sponsoring institutions should consider what is owed to the countries and communities in which their students learn. Finally, she underscores the circumstances under which service-learning programs can truly benefit the cause of global health. PMID:23887005

  9. Good Cascade Impactor Practice (GCIP) and considerations for "in-use" specifications.

    Science.gov (United States)

    Nichols, S C; Mitchell, J P; Shelton, C M; Roberts, D L

    2013-03-01

    The multi-stage cascade impactor (CI) is widely used to determine aerodynamic particle size distributions (APSDs) of orally inhaled products. Its size-fractionating capability depends primarily on the size of nozzles of each stage. Good Cascade Impactor Practice (GCIP) requires that these critical dimensions are linked to the accuracy of the APSD measurement based on the aerodynamic diameter size scale. Effective diameter (Deff) is the critical dimension describing any nozzle array, as it is directly related to stage cut-point size (d50). d50 can in turn be determined by calibration using particles of known aerodynamic diameter, providing traceability to the international length standard. Movements in Deff within manufacturer tolerances for compendial CIs result in the worst case in shifts in d50 of <±10%. Stage mensuration therefore provides satisfactory control of measurement accuracy. The accurate relationship of Deff to d50 requires the CI system to be leak-free, which can be checked by sealing the apparatus at the entry to the induction port and isolating it from the vacuum source and measuring the rate of pressure rise before each use. Mensuration takes place on an infrequent basis compared with the typical interval between individual APSD determinations. Measurement of stage flow resistance (pressure drop; ΔPstage) could enable the user to know that the CI stages are fit for use before every APSD measurement, by yielding an accurate measure of Deff. However, more data are needed to assess the effects of wear and blockage before this approach can be advocated as part of GCIP. PMID:23344853

  10. Biosimilars 101: considerations for U.S. oncologists in clinical practice

    International Nuclear Information System (INIS)

    Biosimilars of biologics used for cancer treatment and supportive care are expected to enter the U.S. market soon. Biosimilars will be highly similar to their reference products, but unlike generic drugs, not identical. Differences between a biosimilar and its reference product may arise because of the complexity of biologics, and differences in the cell lines and processes used during manufacturing. Biosimilars will be approved in the United States through a regulatory pathway based on comparative analytical and clinical studies for their characterization and demonstration of no clinically meaningful differences from their reference products. Unlike generics, initial approval may not include interchangeability, as additional evidence may be required before a biosimilar could be approved as interchangeable with its reference product; interchangeable designation could allow pharmacy-level substitution without prescriber intervention. In some cases, the U.S. Food and Drug Administration (FDA) may extrapolate an indication that has not been formally investigated for the biosimilar but that is approved for the reference product. Robust safety monitoring of all biologics is important to track and accurately attribute adverse events, particularly because their inherent complexity and manufacturing differences make them susceptible to structural changes that can affect safety (e.g., immunogenicity). Accuracy of postapproval safety reports will partly depend on the biosimilar naming approach. Potential cost savings should be evaluated in the context of differences in manufacturers' patient-assistance programs, copayments, and institutional costs. A manufacturer's ability to ensure reliable supply of high-quality biosimilars should also be considered. Broad understanding of these issues is critical for oncologists preparing for their use in clinical practice

  11. Ultrasound and stethoscope as tools in medical education and practice: considerations for the archives

    Science.gov (United States)

    Fakoya, Francis A; du Plessis, Maira; Gbenimacho, Ikechi B

    2016-01-01

    Objectives In recent years, the use and portability of ultrasound has threatened the utility of the stethoscope, with many debating and even advocating its replacement. The authors set out to assess opinions in this regard among faculty within a medical school and specifically within an anatomy department where ultrasound is incorporated into the curriculum from the first term. Methods A debate was elicited during a biweekly Anatomy Journal Club session and was centered on three published papers presented. Several questions were raised regarding the possible replacement of stethoscope – the value of early exposure to students as well as how ultrasound and stethoscope should be considered by physicians, students, and teachers. Results The general consensus was that the stethoscope should not be replaced but should be used in conjunction with emerging portable ultrasound. Caution was given that technology could “overcomplicate” diagnosis and lead to increased tests resulting in increased cost of care. In terms of exposing students to ultrasound, just as the stethoscope requires practice to use effectively, so does the ultrasound and should be introduced as early on as possible. As is the case with the stethoscope, students may not initially appreciate all the finer details on ultrasound; however, continual use would improve skill. Conclusion The stethoscope should always remain part of the physical examination and ultrasound should be used in addition to, not replacement of. As technology advances the need for apprenticeship, training increases and students of the medical profession should be exposed to these technologies as early as possible. Hence, it is not yet time to archive the stethoscope. Perhaps never. PMID:27471420

  12. Polarization in inclusive production at Brookhaven

    International Nuclear Information System (INIS)

    At Brookhaven, Λ's are produced polarized in p-p interactions perpendicular to a horizontal production plane defined by proton-unit vector x Λ-unit vector with their spins pointing down roughly twice as often as up, for a 1 GeV/c transverse Λ momentum. Such a large effect must indicate a simplicity in the underlying dynamics of particle production, even at low transverse momentum. Four BNL experiments are discussed in the context of experiments done at other energies with respect to present (lack of) understanding of the origin of the effect. 3 figures

  13. Theory and practical considerations of multilayer dielectric thin-film stacks in Ag-coated hollow waveguides.

    Science.gov (United States)

    Bledt, Carlos M; Melzer, Jeffrey E; Harrington, James A

    2014-02-01

    This analysis explores the theory and design of dielectric multilayer reflection-enhancing thin film stacks based on high and low refractive index alternating layers of cadmium sulfide (CdS) and lead sulfide (PbS) on silver (Ag)-coated hollow glass waveguides (HGWs) for low loss transmission at midinfrared wavelengths. The fundamentals for determining propagation losses in such multilayer thin-film-coated Ag hollow waveguides is thoroughly discussed, and forms the basis for further theoretical analysis presented in this study. The effects on propagation loss resulting from several key parameters of these multilayer thin film stacks is further explored in order to bridge the gap between results predicted through calculation under ideal conditions and deviations from such ideal models that often arise in practice. In particular, the effects on loss due to the number of dielectric thin film layers deposited, deviation from ideal individual layer thicknesses, and surface roughness related scattering losses are presented and thoroughly investigated. Through such extensive theoretical analysis the level of understanding of the underlying loss mechanisms of multilayer thin-film Ag-coated HGWs is greatly advanced, considerably increasing the potential practical development of next-generation ultralow-loss mid-IR Ag/multilayer dielectric-coated HGWs. PMID:24514252

  14. Practical considerations on frenectomy

    Science.gov (United States)

    Moldoveanu, Lucia; Badea, Florin Ciprian; Odor, Alin A.

    2014-01-01

    Besides surgically classical frenectomy, modern dentistry currently allows its approach by dental laser. Materials and Method: We proposed clinical observation of the results obtained by frenectomy with/without frenoplasty made by laser Er,Cr:YSGG 2780 nm. Results: The patients reported no pain, bleeding, swelling or major discomfort during the postoperative control of the following day. In terms of psycho-emotional reactions, both patients well behave well, the calm being given by no pain, bleeding, suture or edema. Discussions: The accuracy of this method, as well as the use of additional means of healing, allow satisfactory results both for patient and physician. Working parameters depend on the type of laser that is used, in our case Biolase Waterlase MD Turbo, regularly used in Toldimed Clinic in Constanta. Conclusions: Our study reveals that the possibilities regarding the surgical modeling of the lower lip frenulum are higher due to laser than the classical surgical approach. Moreover, a major role in the prevention of relapse by inappropriate healing is represented by the approach of frenectomy accompanied by frenuloplasty.

  15. Clinical trials of boron neutron capture therapy [in humans] [at Beth Israel Deaconess Medical Center][at Brookhaven National Laboratory

    International Nuclear Information System (INIS)

    Assessment of research records of Boron Neutron Capture Therapy was conducted at Brookhaven National Laboratory and Beth Israel Deaconess Medical Center using the Code of Federal Regulations, FDA Regulations and Good Clinical Practice Guidelines. Clinical data were collected FR-om subjects' research charts, and differences in conduct of studies at both centers were examined. Records maintained at Brookhaven National Laboratory were not in compliance with regulatory standards. Beth Israel's records followed federal regulations. Deficiencies discovered at both sites are discussed in the reports

  16. Brookhaven highlights, October 1978-September 1979

    International Nuclear Information System (INIS)

    These highlights present an overview of the major research and development achievements at Brookhaven National Laboratory from October 1978 to September 1979. Specific areas covered include: accelerator and high energy physics programs; high energy physics research; the AGS and improvements to the AGS; neutral beam development; heavy ion fusion; superconducting power cables; ISABELLE storage rings; the BNL Tandem accelerator; heavy ion experiments at the Tandem; the High Flux Beam Reactor; medium energy physics; nuclear theory; atomic and applied physics; solid state physics; neutron scattering studies; x-ray scattering studies; solid state theory; defects and disorder in solids; surface physics; the National Synchrotron Light Source ; Chemistry Department; Biology Department; Medical Department; energy sciences; environmental sciences; energy technology programs; National Center for Analysis of Energy Systems; advanced reactor systems; nuclear safety; National Nuclear Data Center; nuclear materials safeguards; Applied Mathematics Department; and support activities

  17. Brookhaven National Laboratory ADS concepts (USA)

    International Nuclear Information System (INIS)

    Three types of accelerator driven system have been investigated at Brookhaven National Laboratory: the accelerator driven energy producer (ADEP) which is intended for energy production, incineration of minor actinides (MA) and long-lived fission products (LLFP) using a small power accelerator; the Phoenix concept aimed at transmuting large amounts of MA and LLFP using a high current linear accelerator; the accelerator driven particle fuel transmutor (ADPF) which also transmutes the MA and LLFP at high rate by using a high neutron flux. The paper presents these three concepts and other related problems such as fuel and coolant materials, targets, subcriticality and safety issues, the use of Thorium cycle, and non-proliferation issue

  18. How Big Science Came to Long Island: the Birth of Brookhaven Lab (429th Brookhaven Lecture)

    International Nuclear Information System (INIS)

    Robert P. Crease, historian for the U.S. Department of Energy's Brookhaven National Laboratory and Chair of the Philosophy Department at Stony Brook University, will give two talks on the Laboratory's history on October 31 and December 12. Crease's October 31 talk, titled 'How Big Science Came to Long Island: The Birth of Brookhaven Lab,' will cover the founding of the Laboratory soon after World War II as a peacetime facility to construct and maintain basic research facilities, such as nuclear reactors and particle accelerators, that were too large for single institutions to build and operate. He will discuss the key figures involved in starting the Laboratory, including Nobel laureates I.I. Rabi and Norman Ramsey, as well as Donald Dexter Van Slyke, one of the most renowned medical researchers in American history. Crease also will focus on the many problems that had to be overcome in creating the Laboratory and designing its first big machines, as well as the evolving relations of the Laboratory with the surrounding Long Island community and news media. Throughout his talk, Crease will tell fascinating stories about Brookhaven's scientists and their research.

  19. Brookhaven National Laboratory site environmental report for calendar year 1996

    Energy Technology Data Exchange (ETDEWEB)

    Schroeder, G.L.; Paquette, D.E.; Naidu, J.R.; Lee, R.J.; Briggs, S.L.K.

    1998-01-01

    This report documents the results of the Environmental Monitoring Program at Brookhaven National Laboratory and summarizes information about environmental compliance for 1996. To evaluate the effect of Brookhaven National Laboratory`s operations on the local environment, measurements of direct radiation, and of a variety of radionuclides and chemical compounds in the ambient air, soil, sewage effluent, surface water, groundwater, fauna, and vegetation were made at the Brookhaven National Laboratory site and at adjacent sites. The report also evaluates the Laboratory`s compliance with all applicable guides, standards, and limits for radiological and non-radiological emissions and effluents to the environment.

  20. New Brookhaven chief seeks cross-cutting research

    CERN Multimedia

    Jones, D

    2003-01-01

    Brookhaven National Laboratory will pursue opportunities for promoting commercial development of energy systems and other technologies while focusing on the lab's primary mission of basic science research, according to the incoming BNL director, Praveen Chaudhari (1 page).

  1. Brookhaven procedures for statistical analyses of multivariate archaeometric data

    Energy Technology Data Exchange (ETDEWEB)

    Sayre, E.V.

    1976-01-01

    The accumulation in various laboratories of large numbers of multi-component analyses of archaeological artifacts has required the development of increasingly more sophisticated methods for intercomparing these data and analyzing them statistically. A number of different methods of both clustering of specimens into groups and multivariate evaluation of group membership are possible. This paper deals with methods found to be practical and useful in the evaluation of multi-component neutron activation analyses and related studies of archaeological artifacts at Brookhaven National Laboratory. The methods were applied most extensively and successfully to data on pottery and related clays. The subject is treated under the following topics: the use of log normal distributions; clustering methods; preliminary univariate, element-by-element, evaluation of the groups indicated by clustering; multivariate probability calculations; the need for multivariate data handling; use of characteristic vectors of the variance-covariance matrix; standardized multivariant coordinates; the handling of missing data; and auxiliary programs. It is felt that multivariate techniques must ultimately be employed to resolve a set of data fully, but that much can be accomplished by more simple element-to-element methods. 6 figures. (RWR)

  2. Brookhaven at 40 - looking forward as well as back

    International Nuclear Information System (INIS)

    In 1947, the famous Camp Upton Army Base on New York's Long Island switched to a new career as Brookhaven National Laboratory. The reputation the Laboratory has established as a world-class research centre and its continued attraction for scientists looking for exciting possibilities were highlighted on 9-11 September at a symposium and celebration marking forty years of Brookhaven and its parent organization, AUI (Associated Universities Inc)

  3. Report on the Brookhaven Solar Neutrino Experiment

    Science.gov (United States)

    Davis, R. Jr.; Evans, J. C. Jr.

    1976-09-22

    This report is intended as a brief statement of the recent developments and results of the Brookhaven Solar Neutrino Experiment communicated through Professor G. Kocharov to the Leningrad conference on active processes on the sun and the solar neutrino problem. The report summarizes the results of experiments performed over a period of 6 years, from April 1970 to January 1976. Neutrino detection depends upon the neutrino capture reaction /sup 37/Cl(..nu..,e/sup -/)/sup 37/Ar producing the isotope /sup 37/Ar (half life of 35 days). The detector contains 3.8 x 10/sup 5/ liters of C/sub 2/Cl/sub 4/ (2.2 x 10/sup 30/ atoms of /sup 37/Cl) and is located at a depth of 4400 meters of water equivalent (m.w.e.) in the Homestake Gold Mine at Lead, South Dakota, U.S.A. The procedures for extracting /sup 37/Ar and the counting techniques used were described in previous reports. The entire recovered argon sample was counted in a small gas proportional counter. Argon-37 decay events were characterized by the energy of the Auger electrons emitted following the electron capture decay and by the rise-time of the pulse. Counting measurements were continued for a period sufficiently long to observe the decay of /sup 37/Ar.

  4. Nuclear medicine at Brookhaven National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Atkins, H.L.

    1976-01-01

    The Nuclear Medicine Program at the Brookhaven National Laboratory seeks to develop new materials and methods for the investigation of human physiology and disease processes. Some aspects of this research are related to basic research of how radiopharmaceuticals work. Other aspects are directed toward direct applications as diagnostic agents. It is likely that cyclotron-produced positron emitting nuclides will assume greater importance in the next few years. This can be attributed to the ability to label biologically important molecules with high specific activity without affecting biological activity, using /sup 11/C, /sup 13/N, and /sup 15/O. Large quantities of these short-lived nuclides can be administered without excessive radiation dose and newer instrumentation will permit reconstructive axial tomography, providing truly quantitative display of distribution of radioactivity. The /sup 122/Xe-/sup 122/I generator has the potential for looking at rapid dynamic processes. Another generator, the /sup 68/Ge-/sup 68/Ga generator produces a positron emitter for the use of those far removed from cyclotrons. The possibilities for /sup 68/Ga radiopharmaceuticals are as numerous as those for /sup 99m/Tc diagnostic agents.

  5. Geothermal materials development at Brookhaven National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Kukacka, L.E. [Brookhaven National Lab., Upton, NY (United States)

    1997-12-31

    As part of the DOE/OGT response to recommendations and priorities established by industrial review of their overall R&D program, the Geothermal Materials Program at Brookhaven National Laboratory (BNL) is focusing on topics that can reduce O&M costs and increase competitiveness in foreign and domestic markets. Corrosion and scale control, well completion materials, and lost circulation control have high priorities. The first two topics are included in FY 1997 BNL activities, but work on lost circulation materials is constrained by budgetary limitations. The R&D, most of which is performed as cost-shared efforts with U.S. geothermal firms, is rapidly moving into field testing phases. FY 1996 and 1997 accomplishments in the development of lightweight CO{sub 2}-resistant cements for well completions; corrosion resistant, thermally conductive polymer matrix composites for heat exchange applications; and metallic, polymer and ceramic-based corrosion protective coatings are given in this paper. In addition, plans for work that commenced in March 1997 on thermally conductive cementitious grouting materials for use with geothermal heat pumps (GHP), are discussed.

  6. Diagnosis of peste des petits ruminants infection in small ruminants through in-house developed Indirect ELISA: Practical considerations

    Directory of Open Access Journals (Sweden)

    K. K. Sharma

    2015-04-01

    Full Text Available Aim: The work was conducted to diagnose peste des petits ruminants (PPR outbreak through an in house developed indirect ELISA (thereafter referred as iELISA its comparison with other available diagnostic tests and description of practical considerations in its development, utility and limitations. Materials and Methods: An outbreak resembled to PPR occurred in two different places of southern Gujarat viz. Vapi and Navsari, affecting 622 animals, including both goat (n = 476 and sheep (n = 146. Animals displayed the typical signs of PPR at Vapi; however diarrhea was the inconsistent feature in animals of Navsari. The affection caused morbidity of 100% and mortality were 73.68% (n = 392/532 and 56.67% (n = 51/90 in Vapi and Navsari outbreaks, respectively. Relevant ante mortem and post mortem samples were collected from representative animals. At the outset of the epidemic no kit was available with us, so agar gel immunodiffusion (AGID was carried out and a commercial ELISA (cELISA kit was ordered for making diagnosis through antibody demonstration. Meanwhile, an iELISA was developed in house using PPR vaccine as antigen and protein G conjugated HRPO antibody as detector. Histopathology and results of sandwich ELISA were also used to diagnose PPR virus (PPRV in the outbreak. Results: The iELISA developed had detected PPRV antibodies in 22/24 samples (91.66%. Significant difference was observed in disease sensitivity pattern of two species by Chi-square test. While AGID failed to detect antibodies in any sample. Results were reconfirmed by comparing with commercially available cELISA kit. Conclusion: PPR is an economically important disease and for the rapid diagnosis of PPR the in house developed antibody capture iELISA can be a suitable cost effective alternative.

  7. eRHIC. A precision electron-proton/ion collider facility at Brookhaven National Laboratory

    International Nuclear Information System (INIS)

    An electron-proton/ion collider facility (eRHIC) is under consideration at Brookhaven National Laboratory (BNL). Such a new facility will require the design and construction of a new optimized detector profiting from the experience gained from the H1 and ZEUS detectors operated at the HERA collider at DESY. The details of the design will be closely coupled to the design of the interaction region, and thus to the machine development work in general. An overview of the accelerator and detector design concepts will be provided. (author)

  8. eRHIC - A precision electron-proton/ion collider facility at Brookhaven National Laboratory

    International Nuclear Information System (INIS)

    An electron-proton/ion collider facility (eRHIC) is under consideration at Brookhaven National Laboratory (BNL). Such a new facility will require the design and construction of a new optimized detector profiting from the experience gained from the H1 and ZEUS detectors operated at the HERA collider at DESY. The details of the design will be closely coupled to the design of the interaction region, and thus to the machine development work in general. An overview of the accelerator and detector design concepts will be provided

  9. eRHIC - A precision electron-proton/ion collider facility at Brookhaven National Laboratory

    OpenAIRE

    Surrow, Bernd

    2006-01-01

    An electron-proton/ion collider facility (eRHIC) is under consideration at Brookhaven National Laboratory (BNL). Such a new facility will require the design and construction of a new optimized detector profiting from the experience gained from the H1 and ZEUS detectors operated at the HERA collider at DESY. The details of the design will be closely coupled to the design of the interaction region, and thus to the machine development work in general. An overview of the accelerator and detector ...

  10. Actor-Network Theory as a sociotechnical lens to explore the relationship of nurses and technology in practice: methodological considerations for nursing research.

    Science.gov (United States)

    Booth, Richard G; Andrusyszyn, Mary-Anne; Iwasiw, Carroll; Donelle, Lorie; Compeau, Deborah

    2016-06-01

    Actor-Network Theory is a research lens that has gained popularity in the nursing and health sciences domains. The perspective allows a researcher to describe the interaction of actors (both human and non-human) within networked sociomaterial contexts, including complex practice environments where nurses and health technology operate. This study will describe Actor-Network Theory and provide methodological considerations for researchers who are interested in using this sociotechnical lens within nursing and informatics-related research. Considerations related to technology conceptualization, levels of analysis, and sampling procedures in Actor-Network Theory based research are addressed. Finally, implications for future nursing research within complex environments are highlighted. PMID:26531190

  11. BRIDGING THE GAP BETWEEN OLD AND NEW TECHNOLOGY: CONSIDERATION OF INDIGENOUS KNOWLEDGE IN MAIZE PESTS MANAGEMENT PRACTICES IN NIGERIA

    OpenAIRE

    Meludu, Nkiru T.; Adesina, Jimoh B.

    2014-01-01

    Conventional pests management practices are carried out mainly through extensive exposure to chemicals (pesticides) used in agricultural production. The overall ailing effects of these chemical based products to the environment and human health are some of the challenges which appeal to look for alternative farming practices that would minimize the use of pesticides in agricultural production. It is against this background that this study was carried out to determine the perception of the eff...

  12. Designing emissions trading in practice general considerations and experiences from the EU Emissions Trading Scheme (EU ETS)

    OpenAIRE

    Heindl, Peter; Löschel, Andreas

    2012-01-01

    This paper deals with designing emissions trading in practice. After a short introduction to the general idea of emissions trading, practical requirements for the introduction of an emissions trading scheme are considered, including the temporal and spatial dimension as well as administrative requirements and the role of markets. Historical developments regarding emissions trading are discussed. Currently, the largest trading scheme is the EU Emissions Trading Scheme (EU ETS) that aims to red...

  13. Bioethical considerations.

    Science.gov (United States)

    Leyser-Whalen, Ophra; Lawson, Erma; Macdonald, Arlene; Temple, Jeff R; Phelps, John Y

    2014-11-01

    The clinical literature notes that pregnancy has become an expected benefit of solid organ transplant. Establishing "best practices" in the management of this particular transplant population requires careful consideration of the ethical dimensions, broadly speaking, of posttransplant pregnancies and these women's lived experiences. In this article, we present the current clinical and social science posttransplant pregnancy research. We specifically address the psychosocial and ethical issues surrounding preconception counseling and posttransplant health quality of life and mothering and suggest areas for future research. PMID:25151472

  14. Medical-legal considerations in the practice of allergy: personal reflections on lessons learned from an immunotherapy fatality.

    Science.gov (United States)

    Hallett, Jeffrey S

    2004-01-01

    Fatalities after administration of specific allergen immunotherapy are rare occurrences in a general allergy practice, as is medical negligence litigation. The author has experienced both and now relates his personal reflections on the lessons that were learned from the experiences. The twelve lessons that are reviewed encompass observations that are relevant not only to immunotherapy litigation but also to any general medical negligence litigation that one might encounter. Three principles of practice that are specific for allergen immunotherapy administration and that were closely scrutinized during the litigation are also reviewed. PMID:15709451

  15. Brookhaven Lab and Argonne Lab scientists invent a plasma valve

    CERN Multimedia

    2003-01-01

    Scientists from Brookhaven National Laboratory and Argonne National Laboratory have received U.S. patent number 6,528,948 for a device that shuts off airflow into a vacuum about one million times faster than mechanical valves or shutters that are currently in use (1 page).

  16. From heavy ions to light sources at Brookhaven

    International Nuclear Information System (INIS)

    The Brookhaven National Laboratory, recovered from the debacle of the cancelled CBA proton-proton collider project, is now more than busy with an excellent physics programme at the 33 GeV Alternating Gradient Synchrotron and with solid projects for the years to come. (orig.).

  17. Brookhaven National Laboratory site environmental report for calendar year 1995

    Energy Technology Data Exchange (ETDEWEB)

    Naidu, J.R.; Paquette, D.E.; Schroeder, G.L. [eds.] [and others

    1996-12-01

    This report documents the results of the Environmental Monitoring Program at Brookhaven National Laboratory and summarizes information about environmental compliance for 1995. To evaluate the effect of Brookhaven National Laboratory`s operations on the local environment, measurements of direct radiation, and of a variety of radionuclides and chemical compounds in the ambient air, soil, sewage effluent, surface water, groundwater, fauna, and vegetation were made at the Brookhaven National Laboratory site and at adjacent sites. The report also evaluates the Laboratory`s compliance with all applicable guides, standards, and limits for radiological and nonradiological emissions and effluents to the environment. Areas of known contamination are subject to Remedial Investigation/Feasibility Studies under the Inter Agency Agreement established by the Department of Energy, Environmental Protection Agency and the New York Department of Environmental Conservation. Except for identified areas of soil and groundwater contamination, the environmental monitoring data has continued to demonstrate that compliance was achieved with the applicable environmental laws and regulations governing emission and discharge of materials to the environment. Also, the data show that the environmental impacts at Brookhaven National Laboratory are minimal and pose no threat to the public nor to the environment. This report meets the requirements of Department of Energy Orders 5484.1, Environmental Protection, Safety, and Health Protection Information reporting requirements and 5400.1, General Environmental Protection Programs.

  18. Vertical velocity variances and Reynold stresses at Brookhaven

    DEFF Research Database (Denmark)

    Busch, Niels E.; Brown, R.M.; Frizzola, J.A.

    1970-01-01

    Results of wind tunnel tests of the Brookhaven annular bivane are presented. The energy transfer functions describing the instrument response and the numerical filter employed in the data reduction process have been used to obtain corrected values of the normalized variance of the vertical wind...

  19. COMPUTATIONAL SCIENCE AT BROOKHAVEN NATIONAL LABORATORY: THREE SELECTED TOPICS.

    Energy Technology Data Exchange (ETDEWEB)

    DAVENPORT,J.W.DENG,Y.GLIMM,J.SAMULYAK,R.

    2003-09-15

    We present an overview of computational science at Brookhaven National Laboratory (BNL), with selections from three areas: fluids, nanoscience, and biology. The work at BNL in each of these areas is itself very broad, and we select a few topics for presentation within each of them.

  20. Brookhaven National Laboratory moves to the fast lane

    CERN Multimedia

    2006-01-01

    "The U.S. Department of Energy's energy sciences network (ESnet) continues to roll out its next-generation architecture on schedule with the March 14 completion of the Long Island Metropolitan Area Network, connecting Brookhaven National Laboratory (BNL) to the ESnet point of presente (PO) 60 miles away in New York City." (1 page)

  1. Enhancing Socially Responsible Innovation in Industry: Practical Use for Considerations of Social and Ethical Aspects in Industrial Life Science & Technology

    NARCIS (Netherlands)

    Flipse, S.M.

    2013-01-01

    The aim of the study presented in this thesis is to explore to what extent corporate researchers in the field of industrial Life Science & Technology (LST) can consider social and ethical aspects of LST innovation to improve their Research and Development (R&D) practices. Innovators, particularly th

  2. An Approach to Life Skills Group Work with Youth in Transition to Independent Living: Theoretical, Practice, and Operational Considerations

    Science.gov (United States)

    Allen, Terrence T.; Williams, Larry D.

    2012-01-01

    Group work is fundamental to working with youth learning about independent living and in making the tough and challenging transition to independence. The authors, seasoned and experienced group workers and researchers with youth leaving the child welfare system, will present a conceptual framework and set of practices for helping youth gain those…

  3. Regulatory integration: Guidelines and practical considerations for reporting regulatory drivers in DOE contractor Program Plans at the Hanford Reservation

    International Nuclear Information System (INIS)

    Hanford's programs are driven by many regulations and forms of regulatory requirements. Traditionally, DOE activities were subject primarily to DOE authorities and its system of directives. In recent years, DOE programs have increasingly been required to also comply with the mandates of other regulatory agencies such as the U.S. Environmental Protection Agency and the State of Washington Department of Ecology. Program activities, organizations, budgets, and regulatory open-quotes driversclose quotes are essential elements of DOE planning documents such as multi-year program plans. These planning documents provide the foundation for integrated program planning efforts at Hanford. This paper discusses some guidelines that were developed for reporting of regulatory drivers in Hanford program planning documents and considerations that went into their development. The guidelines will appear in the 1994 Hanford Mission Plan Volume I Site Guidance

  4. Regulatory good practices relating to inspection and enforcement. A compilation of the 1989/90 Peer Group discussion considerations as they relate to operational plants. Working material

    International Nuclear Information System (INIS)

    In 1974 the IAEA established a special Nuclear Safety Standards (NUSS) programme under which 5 Codes and 55 Safety Guides have been produced in the areas of Governmental Organization, Siting, Design, Operation and Quality Assurance. The NUSS Codes and Guides are a collection of basic and derived requirements for the safety of nuclear power plants with thermal neutron reactors. They have been developed in a complex manner which ensured the best possible international consensus. This broad consensus is one of the reasons for a relatively general wording of the main principles and is sometimes a cause of problems in their application to the detailed design of nuclear power plants. The requirements, particularly those of the Codes, often need interpretation when applied to specific cases. In many areas national regulations and technical standards are available, but often even these do not answer all questions and only the practice used in applying certain rules fully reflects the outcome of the detailed consideration given to solving individual cases. In order to present further information on the application and interpretation in the NUSS Codes and Safety Guides, the preparation of a series of Safety Practice publications has been initiated. It is hoped that many Member States will be able to benefit from the experience presented in these documents. It is hoped that this publication will be useful for regulators and will also provide information for operating organizations. The document is a compilation of the reports of all of the 1989/90 Peer Group discussions held to consider regulatory inspection and enforcement of good practices. Therefore names of participated countries or the situation of regulatory practices reflect those at time when discussions took place. It identifies those common regulatory features which require continuous reinforcement and the examples of good regulatory practices which were recommended by the senior regulators attending the Peer Group

  5. Considerations on the Improved Integration of Medical Guidelines into Routine Clinical Practice – a Review and Concept Proposal

    Science.gov (United States)

    Beckmann, M. W.; Schlieter, H.; Richter, P.; Wesselmann, S.

    2016-01-01

    Medical guidelines have become established as the standard for the comprehensive synopsis of all available information (scientific trials, expert opinion) on diagnosis and treatment recommendations. The transfer of guidelines to clinical practice and subsequent monitoring has however proven difficult. In particular the potential interaction between guideline developers and guideline users has not been fully utilised. This review article analyses the status quo and existing methodological and technical information solutions supporting the guideline life cycle. It is shown that there are numerous innovative developments that in isolation do not provide comprehensive support. The vision of the “Living Guidelines 2.0” is therefore presented. This outlines the merging of guideline development and implementation on the basis of clinical pathways and guideline-based quality control, and building on this, the generation of information for guideline development and research. PMID:27134291

  6. BROOKHAVEN NATIONAL LABORATORY INSTITUTIONAL PLAN FY2003-2007.

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2003-06-10

    This document presents the vision for Brookhaven National Laboratory (BNL) for the next five years, and a roadmap for implementing that vision. Brookhaven is a multidisciplinary science-based laboratory operated for the U.S. Department of Energy (DOE), supported primarily by programs sponsored by the DOE's Office of Science. As the third-largest funding agency for science in the U.S., one of the DOE's goals is ''to advance basic research and the instruments of science that are the foundations for DOE's applied missions, a base for U.S. technology innovation, and a source of remarkable insights into our physical and biological world, and the nature of matter and energy'' (DOE Office of Science Strategic Plan, 2000 http://www.osti.gov/portfolio/science.htm). BNL shapes its vision according to this plan.

  7. Embracing change: practical and theoretical considerations for successful implementation of technology assisting upper limb training in stroke

    Directory of Open Access Journals (Sweden)

    Hochstenbach-Waelen Ananda

    2012-08-01

    guidance that consists of five phases therapists have to go through. The guidance includes criteria and conditions that motivate therapists, and make it possible for them, to actually use technology in their daily clinical practice. Conclusions The reported requirements are important as guidance for people involved in the development of rehabilitation technology for arm-hand therapy of stroke patients. The stepwise guide provides a tool for facilitating successful implementation of technology in clinical practice, thus meeting future therapy demand.

  8. Brookhaven Accelerator Test Facility photocathode gun and transport beamline

    International Nuclear Information System (INIS)

    We present an analysis of the electron beam emitted from a laser driven photocathode injector (Gun, operating at 2856 MHZ), through a Transport beamline, to the LINAC entrance for the Brookhaven Accelerator Test Facility (ATF). The beam parameters including beam energy, and emittance are calculated. Some of our results, are tabulated and the phase plots of the beam parameters, from Cathode, through the Transport line elements, to the LINAC entrance, are shown

  9. Operation of the Brookhaven AGS with the Booster

    International Nuclear Information System (INIS)

    The Brookhaven Alternating Gradient Synchrotron (AGS) received protons directly from a Linac and heavy ions directly from a Tandem Van de Graaff before 1992. The newly constructed Booster has been brought on line to serve as an injector for the AGS. The operational status of the acceleration of proton and heavy ions through the Booster and the AGS is reviewed. Accelerator improvement programs to increase proton intensity for physics research and to prepare heavy ion beams for RHIC injection are discussed

  10. Brookhaven National Laboratory's multiparticle spectrometer drift chamber system

    International Nuclear Information System (INIS)

    A system of drift chambers is being built to replace the present spark chambers in the Brookhaven National Laboratory's Multiparticle Spectrometer. This system will handle a beam of approx. 3 million particles per second and have a resolution of 200 μm. A summary of the status of the chambers and the custom integrated circuits is presented. The data acquisition system is described. Prototype chambers have been built and tested with results that are consistent with the expected chamber properties

  11. From research to clinical practice: considerations in moving research into people's hands. Personal reflections that may be useful to others.

    Science.gov (United States)

    Rosenbaum, Peter

    2005-01-01

    It may take many years for published clinical research findings to be found, understood, adopted and applied in practice. In recognition of this delay, many jurisdictions and agencies are now promoting a stronger link between research and its dissemination in useable forms that will enable practitioners to access, understand and use new ideas. The purpose of this paper, first presented as a keynote address at the 15th Annual Meeting of the European Academy of Childhood Disability in Oslo in October 2003, is to share experiences of the author and his colleagues at a childhood disability system-linked research centre in Ontario, Canada. The lessons learned include the value of striving to describe one's findings in plain language; writing study reports for parents and children who are involved in research studies; using multiple methods to disseminate one's work; and making explicit the potential importance and applicability of the findings to readers of the work. Engaging end users at many stages of the development and field testing of one's work will enhance buy-in and lend added credibility to the work, as well as influencing content and process as the research unfolds. The result is likely to be greater recognition of 'familiar' aspects of the research and the adoption of relevant findings. PMID:16087550

  12. Practical and theoretical considerations on the use of ICCD imaging for the characterization of non-equilibrium plasmas

    Science.gov (United States)

    Gherardi, Matteo; Puač, Nevena; Marić, Dragana; Stancampiano, Augusto; Malović, Gordana; Colombo, Vittorio; Petrović, Zoran Lj

    2015-12-01

    Over the past decade the use of ICCD cameras as a means for characterizing non-equilibrium plasmas has been steadily increasing. Due to their high sensitivity and high speed gateability, ICCD cameras enable time-resolved studies of the anatomy and, when adopted in conjunction with filters, monochromators, spectrometers or laser systems, time-resolved investigation of physical and chemical properties of non-equilibrium plasma discharges. This paper is meant as an introduction to ICCD technology and its use as a plasma diagnostic technique, discussing the experimental problems typically associated with its use and providing the readers with practical examples and suggestions on how to address them. In particular, the issues of ICCD camera synchronization with the voltage pulse driving the plasma discharge and of investigating small volume discharges are addressed, focusing mainly on the case of non-equilibrium atmospheric pressure plasma jets. Finally, a possible way to achieve absolute calibration of plasma discharge emission is presented and discussed. A wide range of data, mostly unpublished, is provided here to illustrate the points.

  13. Failure to label red blood cells adequately in daily practice using an in vivo method: methodological and clinical considerations

    International Nuclear Information System (INIS)

    This study was conducted to evaluate the frequency and possible causes of poor red blood cell (RBC) labelling when performing equilibrium gated blood pool (GBP) radionuclide angiography at rest with an in vivo method. The influence of the mode of administration on tagging efficiency was studied. The patients were subclassified into four groups according to the way both molecules involved in the tagging procedure were administered. When poor image quality was found, the labelling efficiency was quantified and the frequency of failed tagging in each group was calculated. A significant association was found between poor labelling and the use of a Teflon catheter or butterfly needle for the injection of the stannous agent. In another 737 patients a strict administration protocol was applied to analyse the frequency of poor tagging and its possible causes. Suboptimal image quality was present in 88 patients. Quantitatively confirmed poor tagging was present in 36 of the 88; the remaining 52 patients showed borderline normal labelling. Drug interference was studied by comparing the medications used by the 36 patients showing poor binding with those used by 44 control patients. A significant relationship was found between the use of heparin or chemotherapy and the tagging. A significant correlation was found between advanced age and poor labelling efficiency. Finally, in 36 patients with poor labelling, a second GBP test was performed. This allowed us to evaluate the accuracy of the obtained ejection fraction value when a suboptimal image set is used, and to assess the feasibility of using the new kit in daily practice. (orig.)

  14. BROOKHAVEN NATIONAL LABORATORY SITE ENVIRONMENTAL REPORT FOR CALENDAR YEAR 1994.

    Energy Technology Data Exchange (ETDEWEB)

    NAIDU,J.R.; ROYCE,B.A.

    1995-05-01

    This report documents the results of the Environmental Monitoring Program at Brookhaven National Laboratory and presents summary information about environmental compliance for 1994. To evaluate the effect of Brookhaven National Laboratory's operations on the local environment, measurements of direct radiation, and a variety of radionuclides and chemical compounds in ambient air, soil, sewage effluent, surface water, groundwater, fauna and vegetation were made at the Brookhaven National Laboratory site and at sites adjacent to the Laboratory. Brookhaven National Laboratory's compliance with all applicable guides, standards, and limits for radiological and nonradiological emissions and effluents to the environment were evaluated. Among the permitted facilities, two instances of pH exceedances were observed at recharge basins, possibly related to rain-water run-off to these recharge basins. Also, the discharge from the Sewage Treatment Plant to the Peconic River exceeded. on ten occasions, one each for fecal coliform and 5-day Biochemical Oxygen Demand (avg.) and eight for ammonia nitrogen. The ammonia and Biochemical Oxygen Demand exceedances were attributed to the cold winter and the routine cultivation of the sand filter beds which resulted in the hydraulic overloading of the filter beds and the possible destruction of nitrifying bacteria. The on-set of warm weather and increased aeration of the filter beds via cultivation helped to alleviate this condition. The discharge of fecal coliform may also be linked to this occurrence, in that the increase in fecal coliform coincided with the increased cultivation of the sand filter beds. The environmental monitoring data has identified site-specific contamination of groundwater and soil. These areas are subject to Remedial Investigation/Feasibility Studies under the Inter Agency Agreement. Except for the above, the environmental monitoring data has continued to demonstrate that compliance was achieved with

  15. Some practical and theoretical considerations of personal alpha-particle dosimetry. Joint panel on occupational and environmental research for uranium production in Canada (JP-2)

    International Nuclear Information System (INIS)

    The status of personal α-particle dosimetry in the uranium industry is presented. A brief description of personal dosimeters and prototypes is followed by some theoretical considerations regarding their practical use under steady-state and time-dependent field conditions. It is suggested that, at present, more effort should be placed on the evaluation of dosimeters than in the development of new ones. Also, more information should be gathered from countries which use personal α-particle dosimeters routinely. Furthermore, emphasis is recommended on comparison of personal dosimetry data with experimental data by area monitoring, using continuous monitoring systems, as well as with data by grab-sampling techniques. (author). 44 refs., 1 tab

  16. Brookhaven highlights for fiscal year 1991, October 1, 1990--September 30, 1991

    Energy Technology Data Exchange (ETDEWEB)

    Rowe, M.S.; Cohen, A.; Greenberg, D.; Seubert, L.; Kuper, J.B.H.

    1991-12-31

    This report highlights Brookhaven National Laboratory`s activities for fiscal year 1991. Topics from the four research divisions: Computing and Communications, Instrumentation, Reactors, and Safety and Environmental Protection are presented. The research programs at Brookhaven are diverse, as is reflected by the nine different scientific departments: Accelerator Development, Alternating Gradient Synchrotron, Applied Science, Biology, Chemistry, Medical, National Synchrotron Light Source, Nuclear Energy, and Physics. Administrative and managerial information about Brookhaven are also disclosed. (GHH)

  17. Brookhaven highlights for fiscal year 1991, October 1, 1990--September 30, 1991

    Energy Technology Data Exchange (ETDEWEB)

    Rowe, M.S.; Cohen, A.; Greenberg, D.; Seubert, L.; Kuper, J.B.H.

    1991-01-01

    This report highlights Brookhaven National Laboratory's activities for fiscal year 1991. Topics from the four research divisions: Computing and Communications, Instrumentation, Reactors, and Safety and Environmental Protection are presented. The research programs at Brookhaven are diverse, as is reflected by the nine different scientific departments: Accelerator Development, Alternating Gradient Synchrotron, Applied Science, Biology, Chemistry, Medical, National Synchrotron Light Source, Nuclear Energy, and Physics. Administrative and managerial information about Brookhaven are also disclosed. (GHH)

  18. Making physics: a biography of Brookhaven National Laboratory, 1946-1972, by R.P. Crease

    International Nuclear Information System (INIS)

    Brookhaven National Laboratory was the first major national laboratory built for basic civilian research. From Nobel Prize-winning work in atomic physics to addressing community concerns over radiation leaks, the history of Brookhaven parallels the changing fortunes of 'big science' in the United States. Robert P. Crease brings to life the people, the instruments, the science, and the politics of Brookhaven's first quarter-century.

  19. Brookhaven highlights for fiscal year 1991, October 1, 1990--September 30, 1991

    International Nuclear Information System (INIS)

    This report highlights Brookhaven National Laboratory's activities for fiscal year 1991. Topics from the four research divisions: Computing and Communications, Instrumentation, Reactors, and Safety and Environmental Protection are presented. The research programs at Brookhaven are diverse, as is reflected by the nine different scientific departments: Accelerator Development, Alternating Gradient Synchrotron, Applied Science, Biology, Chemistry, Medical, National Synchrotron Light Source, Nuclear Energy, and Physics. Administrative and managerial information about Brookhaven are also disclosed

  20. Introduction of organic/hydro-organic matrices in inductively coupled plasma optical emission spectrometry and mass spectrometry: A tutorial review. Part II. Practical considerations

    International Nuclear Information System (INIS)

    Graphical abstract: This tutorial review is dedicated to the analysis of organic/hydro-organic matrices by ICP techniques. A state-of-the-art focusing on sample introduction, relevant operating parameters optimization and analytical strategies for elemental quantification is provided. - Highlights: • Practical considerations to perform analyses in organic/hydro-organic matrices. • Description, benefits and drawbacks of recent introduction devices. • Optimization to improve plasma tolerance towards organic/hydro-organic matrices. • Analytical strategies for elemental quantification in organic/hydro-organic matrices. - Abstract: Inductively coupled plasma optical emission spectrometry (ICP-OES) and mass spectrometry (ICP-MS) are increasingly used to carry out analyses in organic/hydro-organic matrices. The introduction of such matrices into ICP sources is particularly challenging and can be the cause of numerous drawbacks. This tutorial review, divided in two parts, explores the rich literature related to the introduction of organic/hydro-organic matrices in ICP sources. Part I provided theoretical considerations associated with the physico-chemical properties of such matrices, in an attempt to understand the induced phenomena. Part II of this tutorial review is dedicated to more practical considerations on instrumentation, instrumental and operating parameters, as well as analytical strategies for elemental quantification in such matrices. Two important issues are addressed in this part: the first concerns the instrumentation and optimization of instrumental and operating parameters, pointing out (i) the description, benefits and drawbacks of different kinds of nebulization and desolvation devices and the impact of more specific instrumental parameters such as the injector characteristics and the material used for the cone; and, (ii) the optimization of operating parameters, for both ICP-OES and ICP-MS. Even if it is at the margin of this tutorial review

  1. Introduction of organic/hydro-organic matrices in inductively coupled plasma optical emission spectrometry and mass spectrometry: A tutorial review. Part II. Practical considerations

    Energy Technology Data Exchange (ETDEWEB)

    Leclercq, Amélie, E-mail: amelie.leclercq@cea.fr [CEA Saclay, DEN, DANS, DPC, SEARS, Laboratoire de développement Analytique Nucléaire Isotopique et Elémentaire, 91191 Gif-sur-Yvette (France); Nonell, Anthony, E-mail: anthony.nonell@cea.fr [CEA Saclay, DEN, DANS, DPC, SEARS, Laboratoire de développement Analytique Nucléaire Isotopique et Elémentaire, 91191 Gif-sur-Yvette (France); Todolí Torró, José Luis, E-mail: jose.todoli@ua.es [Universidad de Alicante, Departamento de Quimica Analitica, Nutricion y Bromatología, Ap. de Correos, 99, 03080 Alicante (Spain); Bresson, Carole, E-mail: carole.bresson@cea.fr [CEA Saclay, DEN, DANS, DPC, SEARS, Laboratoire de développement Analytique Nucléaire Isotopique et Elémentaire, 91191 Gif-sur-Yvette (France); Vio, Laurent, E-mail: laurent.vio@cea.fr [CEA Saclay, DEN, DANS, DPC, SEARS, Laboratoire de développement Analytique Nucléaire Isotopique et Elémentaire, 91191 Gif-sur-Yvette (France); Vercouter, Thomas, E-mail: thomas.vercouter@cea.fr [CEA Saclay, DEN, DANS, DPC, SEARS, Laboratoire de développement Analytique Nucléaire Isotopique et Elémentaire, 91191 Gif-sur-Yvette (France); Chartier, Frédéric, E-mail: frederic.chartier@cea.fr [CEA Saclay, DEN, DANS, DPC, 91191 Gif-sur-Yvette (France)

    2015-07-23

    Graphical abstract: This tutorial review is dedicated to the analysis of organic/hydro-organic matrices by ICP techniques. A state-of-the-art focusing on sample introduction, relevant operating parameters optimization and analytical strategies for elemental quantification is provided. - Highlights: • Practical considerations to perform analyses in organic/hydro-organic matrices. • Description, benefits and drawbacks of recent introduction devices. • Optimization to improve plasma tolerance towards organic/hydro-organic matrices. • Analytical strategies for elemental quantification in organic/hydro-organic matrices. - Abstract: Inductively coupled plasma optical emission spectrometry (ICP-OES) and mass spectrometry (ICP-MS) are increasingly used to carry out analyses in organic/hydro-organic matrices. The introduction of such matrices into ICP sources is particularly challenging and can be the cause of numerous drawbacks. This tutorial review, divided in two parts, explores the rich literature related to the introduction of organic/hydro-organic matrices in ICP sources. Part I provided theoretical considerations associated with the physico-chemical properties of such matrices, in an attempt to understand the induced phenomena. Part II of this tutorial review is dedicated to more practical considerations on instrumentation, instrumental and operating parameters, as well as analytical strategies for elemental quantification in such matrices. Two important issues are addressed in this part: the first concerns the instrumentation and optimization of instrumental and operating parameters, pointing out (i) the description, benefits and drawbacks of different kinds of nebulization and desolvation devices and the impact of more specific instrumental parameters such as the injector characteristics and the material used for the cone; and, (ii) the optimization of operating parameters, for both ICP-OES and ICP-MS. Even if it is at the margin of this tutorial review

  2. Brookhaven National Laboratory site environmental report for calendar year 1990

    International Nuclear Information System (INIS)

    Brookhaven National Laboratory (BNL) carries out basic and applied research in the following fields: high-energy nuclear and solid state physics; fundamental material and structure properties and the interactions of matter; nuclear medicine, biomedical and environmental sciences; and selected energy technologies. In conducting these research activities, it is Laboratory policy to protect the health and safety of employees and the public, and to minimize the impact of BNL operations on the environment. This document is the BNL environmental report for the calendar year 1990 for the safety and Environmental Protection division and corners topics on effluents, surveillance, regulations, assessments, and compliance

  3. Brookhaven National Laboratory site environmental report for calendar year 1991

    International Nuclear Information System (INIS)

    This publication presents the results of BNL's environmental monitoring and compliance effort and provides an assessment of the impact of Brookhaven National Laboratory (BNL) operations on the environment. This document is the responsibility of the Environmental Protection Section of the Safety and Envirorunental Protection Division. Within this Section, the Environmental Monitoring Group (EMG) sample the environment, interpreted the results, performed the impact analysis of the emissions from BNL, and compiled the information presented here. In this effort, other groups of the Section: Compliance; Analytical; Ground Water; and Quality played a key role in addressing the regulatory aspects and the analysis and documentation of the data, respectively

  4. Brookhaven National Laboratory site report for calendar year 1988

    Energy Technology Data Exchange (ETDEWEB)

    Miltenberger, R.P.; Royce, B.A.; Naidu, J.R.

    1989-06-01

    Brookhaven National Laboratory (BNL) is managed by Associated Universities Inc. (AUI). AUI was formed in 1946 by a group of nine universities whose purpose was to create and manage a laboratory in the Northeast in order to advance scientific research in areas of interest to universities, industry, and government. On January 31, 1947, the contract for BNL was approved by the Manhattan District of the Army Corps of Engineers and BNL was established on the former Camp Upton army camp. 54 refs., 21 figs., 78 tabs.

  5. The relativistic heavy ion collider project at Brookhaven

    International Nuclear Information System (INIS)

    The Relativistic Heavy Ion Collider (RHIC) facility will provide collision energies of 100 GeV/nucleon per beam for heavy ions as massive as gold. RHIC will use the existing Brookhaven AGS and Tandem Van de Graaff as injector. The new accelerator facility, which is a nuclear physics initiative, will utilize the existing facilities of the partially completed CBA project. This report discusses the physics motivation for such a facility, the status of the machine design, R and D work and preparations for experiments at RHIC

  6. Brookhaven National Laboratory site report for calendar year 1988

    International Nuclear Information System (INIS)

    Brookhaven National Laboratory (BNL) is managed by Associated Universities Inc. (AUI). AUI was formed in 1946 by a group of nine universities whose purpose was to create and manage a laboratory in the Northeast in order to advance scientific research in areas of interest to universities, industry, and government. On January 31, 1947, the contract for BNL was approved by the Manhattan District of the Army Corps of Engineers and BNL was established on the former Camp Upton army camp. 54 refs., 21 figs., 78 tabs

  7. Proceedings of Brookhaven National Laboratory's fusion/synfuel workshop

    International Nuclear Information System (INIS)

    The fusion synfuels workshop held at Brookhaven National Laboratory (BNL) on August 27-29, 1979 examined the current status of candidate synfuel processes and the R and D required to develop the capability for fusion synfuel production. Participants divided into five working groups, covering the following areas: (1) economics and applications; (2) high-temperature electrolysis; (3) thermochemical processes (including hybrid thermo-electrochemical); (4) blanket and materials; and (5) high-efficiency power cycles. Each working group presented a summary of their conclusions and recommendations to all participants during the third day of the Workshop. These summaries are given

  8. 1995 Annual epidemiologic surveillance report for Brookhaven National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-12-31

    The US Department of Energy`s (DOE) conduct of epidemiologic surveillance provides an early warning system for health problems among workers. This program monitors illnesses and health conditions that result in an absence of five or more consecutive workdays, occupational injuries and illnesses, and disabilities and deaths among current workers. This report summarizes epidemiologic surveillance data collected from Brookhaven National Laboratory (BNL) from January 1, 1995 through December 31, 1995. The data were collected by a coordinator at BNL and submitted to the Epidemiologic Surveillance Data Center, located at Oak Ridge Institute for Science and Education, where quality control procedures and data analyses were carried out.

  9. Brookhaven National Laboratory site environmental report for calendar year 1991

    Energy Technology Data Exchange (ETDEWEB)

    Naidu, J.R.; Royce, B.A.; Miltenberger, R.P.

    1992-09-01

    This publication presents the results of BNL`s environmental monitoring and compliance effort and provides an assessment of the impact of Brookhaven National Laboratory (BNL) operations on the environment. This document is the responsibility of the Environmental Protection Section of the Safety and Envirorunental Protection Division. Within this Section, the Environmental Monitoring Group (EMG) sample the environment, interpreted the results, performed the impact analysis of the emissions from BNL, and compiled the information presented here. In this effort, other groups of the Section: Compliance; Analytical; Ground Water; and Quality played a key role in addressing the regulatory aspects and the analysis and documentation of the data, respectively.

  10. Brookhaven National Laboratory site environmental report for calendar year 1991

    Energy Technology Data Exchange (ETDEWEB)

    Naidu, J.R.; Royce, B.A.; Miltenberger, R.P.

    1992-09-01

    This publication presents the results of BNL's environmental monitoring and compliance effort and provides an assessment of the impact of Brookhaven National Laboratory (BNL) operations on the environment. This document is the responsibility of the Environmental Protection Section of the Safety and Envirorunental Protection Division. Within this Section, the Environmental Monitoring Group (EMG) sample the environment, interpreted the results, performed the impact analysis of the emissions from BNL, and compiled the information presented here. In this effort, other groups of the Section: Compliance; Analytical; Ground Water; and Quality played a key role in addressing the regulatory aspects and the analysis and documentation of the data, respectively.

  11. PROJECT-SPECIFIC TYPE A VERIFICATION FOR THE BROOKHAVEN GRAPHITE RESEARCH REACTOR ENGINEERED CAP, BROOKHAVEN NATIONAL LABORATORY UPTON, NEW YORK DCN 5098-SR-07-0

    Energy Technology Data Exchange (ETDEWEB)

    Evan Harpenau

    2011-07-15

    The Oak Ridge Institute for Science and Education (ORISE) has reviewed the project documentation and data for the Brookhaven Graphite Research Reactor (BGRR) Engineered Cap at Brookhaven National Laboratory (BNL) in Upton, New York. The Brookhaven Science Associates (BSA) have completed removal of affected soils and performed as-left surveys by BSA associated with the BGRR Engineered Cap. Sample results have been submitted, as required, to demonstrate that remediation efforts comply with the cleanup goal of {approx}15 mrem/yr above background to a resident in 50 years (BNL 2011a).

  12. Brookhaven National Laboratory Institutional Plan FY2001--FY2005

    Energy Technology Data Exchange (ETDEWEB)

    Davis, S.

    2000-10-01

    Brookhaven National Laboratory is a multidisciplinary laboratory in the Department of Energy National Laboratory system and plays a lead role in the DOE Science and Technology mission. The Laboratory also contributes to the DOE missions in Energy Resources, Environmental Quality, and National Security. Brookhaven strives for excellence in its science research and in facility operations and manages its activities with particular sensitivity to environmental and community issues. The Laboratory's programs are aligned continuously with the goals and objectives of the DOE through an Integrated Planning Process. This Institutional Plan summarizes the portfolio of research and capabilities that will assure success in the Laboratory's mission in the future. It also sets forth BNL strategies for our programs and for management of the Laboratory. The Department of Energy national laboratory system provides extensive capabilities in both world class research expertise and unique facilities that cannot exist without federal support. Through these national resources, which are available to researchers from industry, universities, other government agencies and other nations, the Department advances the energy, environmental, economic and national security well being of the US, provides for the international advancement of science, and educates future scientists and engineers.

  13. Use of Neutron Irradiations in the Brookhaven Mutations Programme

    International Nuclear Information System (INIS)

    The Co-operative Radiation-Mutations Programme was established at Brookhaven National Laboratory approximately ten years ago to enable plant breeders and agriculturalists to make use of irradiation techniques in plant improvement programmes. The radiation facilities used in the programme are the thermal neutron column at the BGRR reactor, the 250-kVp X-ray machine in the Biology Department, the kilocurie gamma-sources in the Nuclear Engineering Department, a 12 c Co60 gamma-source in the greenhouse, and a 4000 c Co60 source located in a 13-acre field. The development of facilities, techniques, and theory represent Brookhaven's role in this cooperative project whereas the plant material and seed are provided by agricultural experts who are responsible for growing the irradiated material and screening for mutations. More than 150 scientists in 45 states and Puerto Rico are availing themselves of the programme's facilities. Projects have also initiated with Australia, Belgium, Chile, Costa Rica, Denmark, Ecuador, Formosa, Greece, Guatemala, India, Ireland, Italy, Japan, Kenya, Mexico, the Netherlands, Pakistan, Peru, the Philippines, Romania, South Africa.Thailand, Venezuela, West Germany and Yugoslavia. A review of the above cc-operative projects is presented with emphasis on the use of neutrons in mutation induction. (author)

  14. Los estudios de caso en la catalogación: sus contextos teórico-prácticos Case studies in cataloging: theoretical and practical considerations

    Directory of Open Access Journals (Sweden)

    Ariel Alejandro Rodríguez García

    2011-04-01

    Full Text Available La práctica de la catalogación cambió significativamente en el momento en que se introdujo la computación, ahora tecnología de la información, y tras ser considerada como una actividad esencial en la práctica profesional del bibliotecario, y ahora se ha tornado en una actividad compleja envuelta por ciertos lenguajes como la semántica, la sintaxis, la pragmática y otras reglas que gobiernan su interpretación. El propósito de este trabajo es analizar por qué los estudios de caso de la catalogación han sido empleados sólo para describir situaciones particulares y no han contribuido a formular generalizaciones. Es decir, por qué se han utilizado únicamente con fines instrumentales y se han diseñado a partir de modelos explicativos y parciales. Una de las principales aportaciones de este texto es que se considere al estudio de caso como soporte para respaldar lo que teóricamente se está denominando Bibliotecología Basada en Evidencias. Adoptar la metodología del estudio de caso les permitirá a los catalogadores tomar decisiones, observar e interactuar con la finalidad de integrar lo empírico con lo teórico.The practice of cataloging underwent vast changes when the computer was introduced and opened the field of what we now call information technology now essential in the practice of the professional librarian, involving highly specialized pragmatics, languages, syntax and interpretative rules. The purpose of this research is to explain why case studies in the field of cataloging have been used merely descriptively, while failing to draw out general principles. These studies, moreover, have been used for instrumental ends, having been designed from explicatory and fragmentary models. As such, this paper argues for case study praxis as a support for the theory of Evidence Based Librarianship. By adopting the case study methodology, cataloguers will enjoy powerful decision making parameters that happily conjoin real

  15. Deriving cleanup guidelines for radionuclides at Brookhaven National Laboratory

    International Nuclear Information System (INIS)

    Past activities at Brookhaven National Laboratory (BNL) resulted in soil and groundwater contamination. As a result, BNL was designated a Superfund site under the Comprehensive Environmental Response Compensation and Liability Act (CERCLA). BNL's Office of Environmental Restoration (OER) is overseeing environmental restoration activities at the Laboratory. With the exception of radium, there are no regulations or guidelines to establish cleanup guidelines for radionuclides in soils at BNL. BNL must derive radionuclide soil cleanup guidelines for a number of Operable Units (OUs) and Areas of Concern (AOCs). These guidelines are required by DOE under a proposed regulation for radiation protection of public health and the environment as well as to satisfy the requirements of CERCLA. The objective of this report is to propose a standard approach to deriving risk-based cleanup guidelines for radionuclides in soil at BNL. Implementation of the approach is briefly discussed

  16. Summary of failure analysis activities at Brookhaven National Laboratory

    International Nuclear Information System (INIS)

    Brookhaven National Laboratory has for many years conducted examinations related to the failures of nuclear materials and components. These examinations included the confirmation of root cause analyses, the determination of the causes of failure, identification of the species that accelerate corrosion, and comparison of the results of nondestructive examinations with those obtained by destructive examination. The results of those examinations, which had previously appeared in various formats (formal and informal reports, journal articles, etc.), have been collected together and summarized in the present report. The report is divided into sections according to the general subject matter (for example, corrosion, fatigue, etc.). Each section presents summaries of the information contained in specific reports and publications, all of which are fully identified as to title, authors, report number or journal reference, date of publication, and FIN number under which the work was performed

  17. Upgrade of the Brookhaven 200 MeV linac

    International Nuclear Information System (INIS)

    The Brookhaven 200 MeV linac serves as the injector for the AGS Booster, as well as delivering beam to the Biomedical Isotope Resource Center. During the past year, many linac systems have been upgraded to allow operation at 2.5 times higher average current (150 μA). This was achieved by an increase in rep-rate from 5 to 7.5 Hz, an increase in beam current from 25 mA to 37 mA, and a slight increase in pulse width to ∼530 μs. Additional upgrades were made to improve reliability and modernize old systems. This paper describes improvements made in the 35 keV and 750 keV beam transport, 200 MeV beam transport, rf transmission line, rf power supplies, control systems, and instrumentation

  18. Digital transverse beam dampers from the Brookhaven AGS

    International Nuclear Information System (INIS)

    A wide band, digital damper system has been developed and is in use at the Brookhaven Alternating Gradient Synchrotron (AGS). The system consists of vertical and horizontal capacitive pickups, analog and digital processing electronics, four 500 Watt wide band power amplifiers, and two pairs of strip line beam kickers. The system is currently used to damp transverse coherent instabilities and injection errors, in both planes, for protons and all species of heavy ions. This paper discusses the system design and operation, particularly with regard to stabilization of the high intensity proton beam. The analog and digital signal processing techniques used to achieve optimum results are discussed. Operational data showing the effect of the damping are presented

  19. Development of H/sup -/ sources at Brookhaven National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Prelec, K.

    1977-01-01

    Negative hydrogen ion sources have been developed at Brookhaven National Laboratory for several years, with the initial goal to design a source for accelerator applications and later on to design a large unit for applications in neutral beam injectors of magnetic fusion devices. Three types of sources were investigated, a hollow discharge duoplasmatron yielding H/sup -/currents up to 60 mA, a Penning source yielding H/sup -/ currents up to 440 mA, and a magnetron source yielding H/sup -/ currents up to 1 A. All sources operate with a mixture of hydrogen gas and cesium vapors, and H/sup -/ ions are most likely produced on cesium covered electrode surfaces. A larger model of a Penning/magnetron source was constructed and will be tested soon; it incorporates among other new features a system for the cooling of the cathode.

  20. High field magnet program at Brookhaven National Laboratory

    CERN Document Server

    Ghosh, A; Muratore, J; Parker, B; Sampson, W; Wanderer, P J; Willen, E

    2000-01-01

    The magnet program at Brookhaven National Laboratory (BNL) is focussed on superconducting magnets for particle accelerators. The effort includes magnet production at the laboratory and in industry, magnet R&D, and test facilities for magnets and superconductors. Nearly 2000 magnets-dipoles, quadrupoles, sextupoles and correctors for the arc and insertion regions-were produced for the Relativistic Heavy Ion Collider (RHIC), which is being commissioned. Currently, production of helical dipoles for the polarized proton program at RHIC, insertion region dipoles for the Large Hadron Collider (LHC) at CERN, and an insertion magnet system for the Hadron-Elektron-Ring- Analage (HERA) collider at Deutsches Elektronen-Synchrotron (DESY) is underway. The R&D effort is exploring dipoles with fields above 10 T for use in post-LHC colliders. Brittle superconductors-Nb/sub 3/Sn or HTS-are being used for these magnets. The superconductor test facility measures short-sample currents and other characteristics of sample...

  1. Deriving cleanup guidelines for radionuclides at Brookhaven National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Meinhold, A.F.; Morris, S.C.; Dionne, B.; Moskowitz, P.D.

    1997-01-01

    Past activities at Brookhaven National Laboratory (BNL) resulted in soil and groundwater contamination. As a result, BNL was designated a Superfund site under the Comprehensive Environmental Response Compensation and Liability Act (CERCLA). BNL`s Office of Environmental Restoration (OER) is overseeing environmental restoration activities at the Laboratory. With the exception of radium, there are no regulations or guidelines to establish cleanup guidelines for radionuclides in soils at BNL. BNL must derive radionuclide soil cleanup guidelines for a number of Operable Units (OUs) and Areas of Concern (AOCs). These guidelines are required by DOE under a proposed regulation for radiation protection of public health and the environment as well as to satisfy the requirements of CERCLA. The objective of this report is to propose a standard approach to deriving risk-based cleanup guidelines for radionuclides in soil at BNL. Implementation of the approach is briefly discussed.

  2. First experiences with a fastbus system at Brookhaven

    International Nuclear Information System (INIS)

    A new concept in high energy data acquisition systems called Fastbus has been developed and implemented at Brookhaven. The system which is capable of sub-gigabit/sec speeds has been operating for some time now. A number of modules including an on-bus processor, a PDP11 interface, 32 channel coincidence latches, a 16 channel scaler, a 32 channel μ-clock device, a 60 nsec memory and a predetermined time module have been developed and built. Features of the system include extensive use of ECL logic and a water cooled crate with conduction heat transfer within a module. The system is used in an on-line experiment at the AGS. Operating experience will be discussed

  3. Thermal performance of the Brookhaven natural thermal storage house

    Energy Technology Data Exchange (ETDEWEB)

    Ghaffari, H. T.; Jones, R. F.

    1981-01-01

    In the Brookhaven natural thermal storage house, an energy-efficient envelope, passive solar collectors, and a variety of energy conservation methods are incorporated. The thermal characteristics of the house during the tested heating season are evaluated. Temperature distributions at different zones are displayed, and the effects of extending heating supply ducts only to the main floor and heating return ducts only from the second floor are discussed. The thermal retrievals from the structure and the passive collectors are assessed, and the total conservation and passive solar contributions are outlined. Several correlation factors relating these thermal behaviors are introduced, and their diurnal variations are displayed. Finally, the annual energy requirements, and the average load factors are analyzed and discussed.

  4. Practice.

    Science.gov (United States)

    Chambers, David W

    2008-01-01

    Practice refers to a characteristic way professionals use common standards to customize solutions to a range of problems. Practice includes (a) standards for outcomes and processes that are shared with one's colleagues, (b) a rich repertoire of skills grounded in diagnostic acumen, (c) an ability to see the actual and the ideal and work back and forth between them, (d) functional artistry, and (e) learning by doing that transcends scientific rationality. Communities of practice, such as dental offices, are small groups that work together in interlocking roles to achieve these ends. PMID:19413050

  5. WILDLAND FIRE MANAGEMENT PLAN FOR BROOKHAVEN NATIONAL LABORATORY.

    Energy Technology Data Exchange (ETDEWEB)

    ENVIRONMENTAL AND WASTE MANAGEMENT SERVICES DIVISION

    2003-09-01

    This Wildland Fire Management Plan (FMP) for Brookhaven National Lab (BNL) and the Upton Ecological and Research Reserve (Upton Reserve) is based on the U.S. Fish & Wildlife Service (FWS) fire management planning procedures and was developed in cooperation with the Department of Energy (DOE) by Brookhaven Science Associates. As the Upton Reserve is contained within the BNL 5,265-acre site, it is logical that the plan applies to both the Upton Reserve and BNL. The Department of the Interior policy for managing wildland fires requires that all areas managed by FWS that can sustain fire must have an FMP that details fire management guidelines for operational procedures and specifies values to be protected or enhanced. Fire management plans provide guidance on fire preparedness, fire prevention, wildfire suppression, and the use of controlled, ''prescribed'' fires and mechanical means to control the amount of available combustible material. Values reflected in the BNL/Upton Reserve Wildland FMP include protecting life and public safety; Lab properties, structures and improvements; cultural and historical sites; neighboring private and public properties; and endangered and threatened species and species of concern. Other values supported by the plan include the enhancement of fire-dependent ecosystems at BNL and the Upton Reserve. This FMP will be reviewed periodically to ensure the fire program advances and evolves with the missions of FWS, BNL, and the Upton Reserve. This Fire Management Plan is a modified version of the Long Island National Wildlife Refuge Complex Fire plan (updated in 2000), which contains all FWS fire plan requirements and is presented in the format specified by the national template for fire management plans adopted under the National Fire Plan. The DOE is one of the signatory agencies on the National Fire Plan. FWS shall be, through an Interagency Agreement dated November 2000 (Appendix C), responsible for coordinating and

  6. Proto-2, an ALICE detector prototype, part of the STAR experiment at the Brookhaven National Laboratory

    CERN Multimedia

    2002-01-01

    Proto-2, an LAICE detector prototype, overcame its prototype status to become a real part of the SDTAR, epxeriment at the US Brookhaven National Laboratory. After more than two years across the ocean, it has just arrived back at CERN.

  7. DOE handbook: Design considerations

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-04-01

    The Design Considerations Handbook includes information and suggestions for the design of systems typical to nuclear facilities, information specific to various types of special facilities, and information useful to various design disciplines. The handbook is presented in two parts. Part 1, which addresses design considerations, includes two sections. The first addresses the design of systems typically used in nuclear facilities to control radiation or radioactive materials. Specifically, this part addresses the design of confinement systems and radiation protection and effluent monitoring systems. The second section of Part 1 addresses the design of special facilities (i.e., specific types of nonreactor nuclear facilities). The specific design considerations provided in this section were developed from review of DOE 6430.1A and are supplemented with specific suggestions and considerations from designers with experience designing and operating such facilities. Part 2 of the Design Considerations Handbook describes good practices and design principles that should be considered in specific design disciplines, such as mechanical systems and electrical systems. These good practices are based on specific experiences in the design of nuclear facilities by design engineers with related experience. This part of the Design Considerations Handbook contains five sections, each of which applies to a particular engineering discipline.

  8. DOE handbook: Design considerations

    International Nuclear Information System (INIS)

    The Design Considerations Handbook includes information and suggestions for the design of systems typical to nuclear facilities, information specific to various types of special facilities, and information useful to various design disciplines. The handbook is presented in two parts. Part 1, which addresses design considerations, includes two sections. The first addresses the design of systems typically used in nuclear facilities to control radiation or radioactive materials. Specifically, this part addresses the design of confinement systems and radiation protection and effluent monitoring systems. The second section of Part 1 addresses the design of special facilities (i.e., specific types of nonreactor nuclear facilities). The specific design considerations provided in this section were developed from review of DOE 6430.1A and are supplemented with specific suggestions and considerations from designers with experience designing and operating such facilities. Part 2 of the Design Considerations Handbook describes good practices and design principles that should be considered in specific design disciplines, such as mechanical systems and electrical systems. These good practices are based on specific experiences in the design of nuclear facilities by design engineers with related experience. This part of the Design Considerations Handbook contains five sections, each of which applies to a particular engineering discipline

  9. Environmental Survey preliminary report, Brookhaven National Laboratory, Upton, New York

    Energy Technology Data Exchange (ETDEWEB)

    1988-06-01

    This report presents the preliminary findings from the first phase of the Environmental Survey of the United States Department of Energy (DOE) Brookhaven National Laboratory (BNL) conducted April 6 through 17, 1987. The Survey is being conducted by an interdisciplinary team of environmental specialists, led and managed by the Office of Environment, Safety and Health's Office of Environmental Audit. Individual team components are being supplied by a private contractor. The objective of the Survey is to identify environmental problems and areas of environmental risk associated with BNL. The Survey covers all environmental media and all areas of environmental regulation. It is being performed in accordance with the DOE Environmental Survey Manual. This phase of the Survey involves the review of existing site environmental data, observations of the operations carried on at BNL, and interviews with site personnel. The Survey team developed a Sampling and Analysis Plan to assist in further assessing specific environmental problems identified during its on-site activities. The Sampling and Analysis Plan will be executed by Oak Ridge National Laboratory. When completed, the results will be incorporated into the BNL Environmental Survey Interim Report. The Interim Report will reflect the final determinations of the BNL Survey. 80 refs., 24 figs., 48 tabs.

  10. Tiger Team assessment of the Brookhaven National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    1990-06-01

    This report documents the results of the Department of Energy's (DOE's) Tiger Team Assessment conducted at Brookhaven National Laboratory (BNL) in Upton, New York, between March 26 and April 27, 1990. The BNL is a multiprogram laboratory operated by the Associated Universities, Inc., (AUI) for DOE. The purpose of the assessment was to provide the status of environment, safety, and health (ES H) programs at the laboratory. The scope of the assessment included a review of management systems and operating procedures and records; observations of facility operations; and interviews at the facilities. Subteams in four areas performed the review: ES H, Occupational Safety and Health, and Management and Organization. The assessment was comprehensive, covering all areas of ES H activities and waste management operations. Compliance with applicable Federal, State, and local regulations; applicable DOE Orders; and internal BNL requirements was assessed. In addition, the assessment included an evaluation of the adequacy and effectiveness of the DOE and the site contractor, Associated Universities, Inc. (AUI), management, organization, and administration of the ES H programs at BNL. This volume contains appendices.

  11. Environmental Survey preliminary report, Brookhaven National Laboratory, Upton, New York

    International Nuclear Information System (INIS)

    This report presents the preliminary findings from the first phase of the Environmental Survey of the United States Department of Energy (DOE) Brookhaven National Laboratory (BNL) conducted April 6 through 17, 1987. The Survey is being conducted by an interdisciplinary team of environmental specialists, led and managed by the Office of Environment, Safety and Health's Office of Environmental Audit. Individual team components are being supplied by a private contractor. The objective of the Survey is to identify environmental problems and areas of environmental risk associated with BNL. The Survey covers all environmental media and all areas of environmental regulation. It is being performed in accordance with the DOE Environmental Survey Manual. This phase of the Survey involves the review of existing site environmental data, observations of the operations carried on at BNL, and interviews with site personnel. The Survey team developed a Sampling and Analysis Plan to assist in further assessing specific environmental problems identified during its on-site activities. The Sampling and Analysis Plan will be executed by Oak Ridge National Laboratory. When completed, the results will be incorporated into the BNL Environmental Survey Interim Report. The Interim Report will reflect the final determinations of the BNL Survey. 80 refs., 24 figs., 48 tabs

  12. CULTURAL RESOURCE MANAGEMENT PLAN FOR BROOKHAVEN NATIONAL LABORATORY.

    Energy Technology Data Exchange (ETDEWEB)

    DAVIS, M.

    2005-04-01

    The Cultural Resource Management Plan (CRMP) for Brookhaven National Laboratory (BNL) provides an organized guide that describes or references all facets and interrelationships of cultural resources at BNL. This document specifically follows, where applicable, the format of the U.S. Department of Energy (DOE) Environmental Guidelines for Development of Cultural Resource Management Plans, DOE G 450.1-3 (9-22-04[m1]). Management strategies included within this CRMP are designed to adequately identify the cultural resources that BNL and DOE consider significant and to acknowledge associated management actions. A principal objective of the CRMP is to reduce the need for additional regulatory documents and to serve as the basis for a formal agreement between the DOE and the New York State Historic Preservation Officer (NYSHPO). The BNL CRMP is designed to be a ''living document.'' Each section includes identified gaps in the management plan, with proposed goals and actions for addressing each gap. The plan will be periodically revised to incorporate new documentation.

  13. Brookhaven National Laboratory 2008 Site Environment Report Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    Brookhaven National Laboratory

    2009-10-01

    Brookhaven National Laboratory (BNL) prepares an annual Site Environmental Report (SER) in accordance with DOE Order 231.1A, Environment, Safety and Health Reporting of the U.S. Department of Energy. The report is written to inform the public, regulators, employees, and other stakeholders of the Laboratory's environmental performance during the calendar year in review. Volume I of the SER summarizes environmental data; environmental management performance; compliance with applicable DOE, federal, state, and local regulations; and performance in restoration and surveillance monitoring programs. BNL has prepared annual SERs since 1971 and has documented nearly all of its environmental history since the Laboratory's inception in 1947. Volume II of the SER, the Groundwater Status Report, also is prepared annually to report on the status of and evaluate the performance of groundwater treatment systems at the Laboratory. Volume II includes detailed technical summaries of groundwater data and its interpretation, and is intended for internal BNL users, regulators, and other technically oriented stakeholders. A brief summary of the information contained in Volume II is included in this volume in Chapter 7, Groundwater Protection. Both reports are available in print and as downloadable files on the BNL web page at http://www.bnl.gov/ewms/ser/. An electronic version on compact disc is distributed with each printed report. In addition, a summary of Volume I is prepared each year to provide a general overview of the report, and is distributed with a compact disc containing the full report.

  14. In vivo neutron activation facility at Brookhaven National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Ma, R.; Yasumura, Seiichi; Dilmanian, F.A.

    1997-11-01

    Seven important body elements, C, N, Ca, P, K, Na, and Cl, can be measured with great precision and accuracy in the in vivo neutron activation facilities at Brookhaven National Laboratory. The facilities include the delayed-gamma neutron activation, the prompt-gamma neutron activation, and the inelastic neutron scattering systems. In conjunction with measurements of total body water by the tritiated-water dilution method several body compartments can be defined from the contents of these elements, also with high precision. In particular, body fat mass is derived from total body carbon together with total body calcium and nitrogen; body protein mass is derived from total body nitrogen; extracellular fluid volume is derived from total body sodium and chlorine; lean body mass and body cell mass are derived from total body potassium; and, skeletal mass is derived from total body calcium. Thus, we suggest that neutron activation analysis may be valuable for calibrating some of the instruments routinely used in clinical studies of body composition. The instruments that would benefit from absolute calibration against neutron activation analysis are bioelectric impedance analysis, infrared interactance, transmission ultrasound, and dual energy x-ray/photon absorptiometry.

  15. Rebuilding the Brookhaven high flux beam reactor: A feasibility study

    International Nuclear Information System (INIS)

    After nearly thirty years of operation, Brookhaven's High Flux Beam Reactor (HFBR) is still one of the world's premier steady-state neutron sources. A major center for condensed matter studies, it currently supports fifteen separate beamlines conducting research in fields as diverse as crystallography, solid-state, nuclear and surface physics, polymer physics and structural biology and will very likely be able to do so for perhaps another decade. But beyond that point the HFBR will be running on borrowed time. Unless appropriate remedial action is taken, progressive radiation-induced embrittlement problems will eventually shut it down. Recognizing the HFBR's value as a national scientific resource, members of the Laboratory's scientific and reactor operations staffs began earlier this year to consider what could be done both to extend its useful life and to assure that it continues to provide state-of-the-art research facilities for the scientific community. This report summarizes the findings of that study. It addresses two basic issues: (i) identification and replacement of lifetime-limiting components and (ii) modifications and additions that could expand and enhance the reactor's research capabilities

  16. HOM identification by bead pulling in the Brookhaven ERL cavity

    Energy Technology Data Exchange (ETDEWEB)

    Hahn H.; Calaga, R.; Jain, P.; Johnson, E.C.; Xu, W.

    2012-06-25

    Several past measurements of the Brookhaven ERL at superconducting temperature produced a long list of higher order modes (HOMs). The Niobium 5-cell cavity is terminated with HOM ferrite dampers that successfully reduce the Q-factors to tolerable levels. However, a number of undamped resonances with Q {ge} 10{sup 6} were found at 4 K and their mode identification remained as a goal for this paper. The approach taken here consists in taking different S{sub 21} measurements on a copper cavity replica of the ERL which can be compared with the actual data and also with Microwave Studio computer simulations. Several different S{sub 21} transmission measurements are used, including those taken from the fundamental input coupler to the pick-up probe across the cavity, between probes in a single cell, and between beam-position monitor probes in the beam tubes. Mode identification is supported by bead pulling with a metallic needle or a dielectric sphere that are calibrated in the fundamental mode. This paper presents results for HOMs in the first two dipole bands with the prototypical 958 MHz trapped mode, the lowest beam tube resonances, and high-Q modes in the first quadrupole band and beyond.

  17. HOM identification by bead pulling in the Brookhaven ERL cavity

    Energy Technology Data Exchange (ETDEWEB)

    Hahn, H., E-mail: hahnh@bnl.gov [Collider–Accelerator Department, Brookhaven National Laboratory, Upton, NY 11973 (United States); Calaga, R. [Collider–Accelerator Department, Brookhaven National Laboratory, Upton, NY 11973 (United States); European Organization for Nuclear Research, 1211 Geneva (Switzerland); Jain, Puneet; Johnson, Elliott C. [Physics and Astronomy Department, Stony Brook University, Stony Brook, NY 117943 (United States); Xu, Wencan [Collider–Accelerator Department, Brookhaven National Laboratory, Upton, NY 11973 (United States)

    2014-01-11

    Exploratory measurements of the Brookhaven Energy Recovery Linac (ERL) cavity at superconducting temperature produced a long list of high order modes (HOMs). The niobium 5-cell cavity is terminated at each end with HOM ferrite dampers that successfully reduce the Q-factors to levels required to avoid beam break up (BBU) instabilities. However, a number of un-damped resonances with Q≥10{sup 6} were found at 4 K and their mode identification forms the focus of this paper. The approach taken here consists of bead pulling on a copper (Cu) replica of the ERL cavity with dampers involving various network analyzer measurements. Several different S{sub 21} transmission measurements are used, including those taken from the fundamental input coupler to the pick-up probe across the cavity, others between beam-position monitor probes in the beam tubes, and also between probes placed into the cells. The bead pull technique suitable for HOM identification with a metallic needle or dielectric bead is detailed. This paper presents the results for HOMs in the first two dipole bands, the un-damped modes in the first quadrupole band, and the identification of several high-Q modes beyond.

  18. Design of the beryllium window for Brookhaven Linac Isotope Producer

    Energy Technology Data Exchange (ETDEWEB)

    Nayak, S. [Brookhaven National Lab. (BNL), Upton, NY (United States); Mapes, M. [Brookhaven National Lab. (BNL), Upton, NY (United States); Raparia, D. [Brookhaven National Lab. (BNL), Upton, NY (United States)

    2015-11-01

    In the Brookhaven Linac Isotope Producer (BLIP) beam line, there were two Beryllium (Be) windows with an air gap to separate the high vacuum upstream side from low vacuum downstream side. There had been frequent window failures in the past which affected the machine productivity and increased the radiation dose received by workers due to unplanned maintenance. To improve the window life, design of Be window is reexamined. Detailed structural and thermal simulations are carried out on Be window for different design parameters and loading conditions to come up with better design to improve the window life. The new design removed the air gap and connect the both beam lines with a Be window in-between. The new design has multiple advantages such as 1) reduces the beam energy loss (because of one window with no air gap), 2) reduces air activation due to nuclear radiation and 3) increased the machine reliability as there is no direct pressure load during operation. For quick replacement of this window, an aluminum bellow coupled with load binder was designed. There hasn’t been a single window failure since the new design was implemented in 2012.

  19. Design of the beryllium window for Brookhaven Linac Isotope Producer

    International Nuclear Information System (INIS)

    In the Brookhaven Linac Isotope Producer (BLIP) beam line, there were two Beryllium (Be) windows with an air gap to separate the high vacuum upstream side from low vacuum downstream side. There had been frequent window failures in the past which affected the machine productivity and increased the radiation dose received by workers due to unplanned maintenance. To improve the window life, design of Be window is reexamined. Detailed structural and thermal simulations are carried out on Be window for different design parameters and loading conditions to come up with better design to improve the window life. The new design removed the air gap and connect the both beam lines with a Be window in-between. The new design has multiple advantages such as 1) reduces the beam energy loss (because of one window with no air gap), 2) reduces air activation due to nuclear radiation and 3) increased the machine reliability as there is no direct pressure load during operation. For quick replacement of this window, an aluminum bellow coupled with load binder was designed. There hasn't been a single window failure since the new design was implemented in 2012.

  20. The program of the ALARA Center at Brookhaven National Laboratory

    International Nuclear Information System (INIS)

    In 1984 the Brookhaven National Laboratory was asked by the Nuclear Regulatory Commission to set up a Center to monitor dose-reduction efforts in the US and abroad and to focus the industry's attention on ALARA. The paper summarizes the main work of the ALARA Center between 1984 and 1992. The Center maintains nine data bases for the NRC and the Nuclear Power Industry. These databases are constantly updated and access to them is provided through a personal computer and a modem and by periodic publications in the form of a newsletter and NUREG reports. Also described briefly are eight other projects related to dose-reduction at nuclear power plants that the Center has carried out for the NRC. Among these are projects that analyze the cost-effectiveness of engineering modifications, look at worldwide activities at dose reduction and compare US and foreign dose experience, examine high-dose worker groups and high-dose jobs, develop optimum techniques to control contamination at nuclear plants, and look at the doses being received by men and women in all sectors of the nuclear industry

  1. Tiger Team assessment of the Brookhaven National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    1990-06-01

    This report documents the results of the Department of Energy's (DOE's) Tiger Team Assessment conducted at Brookhaven National Laboratory (BNL) in Upton, New York, between March 26 and April 27, 1990. The BNL is a multiprogram laboratory operated by the Associated Universities, Inc., (AUI) for DOE. The purpose of the assessment was to provide the status of environment, safety, and health (ES H) programs at the Laboratory. The scope of the assessment included a review of management systems and operating procedures and records; observations of facility operations; and interviews at the facilities. Subteams in four areas performed the review: ES H, Occupational Safety and Health, and Management and Organization. The assessment was comprehensive, covering all areas of ES H activities and waste management operations. Compliance with applicable Federal, State, and local regulations; applicable DOE Orders; and internal BNL requirements was assessed. In addition, the assessment included an evaluation of the adequacy and effectiveness of the DOE and the site contractor, Associated Universities, Inc. (AUI), management, organization, and administration of the ES H programs at BNL.

  2. HOM identification by bead pulling in the Brookhaven ERL cavity

    CERN Document Server

    Hahn, H; Jain, Puneet; Johnson, Elliott C; Xu, Wencan

    2014-01-01

    Exploratory measurements of the Brookhaven Energy Recovery Linac (ERL) cavity at superconducting temperature produced a long list of high order modes (HOMs). The niobium 5-cell cavity is terminated at each end with HOM ferrite dampers that successfully reduce the Q-factors to levels required to avoid beam break up (BBU) instabilities. However, a number of un-damped resonances with Q≥106 were found at 4 K and their mode identification forms the focus of this paper. The approach taken here consists of bead pulling on a copper (Cu) replica of the ERL cavity with dampers involving various network analyzer measurements. Several different S21 transmission measurements are used, including those taken from the fundamental input coupler to the pick-up probe across the cavity, others between beam-position monitor probes in the beam tubes, and also between probes placed into the cells. The bead pull technique suitable for HOM identification with a metallic needle or dielectric bead is detailed. This paper presents the...

  3. Brookhaven National Laboratory site environmental report for calendar year 1993

    Energy Technology Data Exchange (ETDEWEB)

    Naidu, J.R.; Royce, B.A. [eds.

    1994-05-01

    This report documents the results of the Environmental Monitoring Program at BNL and presents summary information about environmental compliance for 1993. To evaluate the effect of BNL operations on the local environment, measurements of direct radiation, and a variety of radionuclides and chemical compounds in ambient air, soil, sewage effluent, surface water, ground water and vegetation were made at the BNL site and at sites adjacent to the Laboratory. Brookhaven National Laboratory`s compliance with all applicable guides, standards, and limits for radiological and nonradiological emissions to the environment were evaluated. Among the permitted facilities, two instances, of pH exceedances were observed at recharge basins, possible related to rain-water run-off to these recharge basins. Also, the discharge from the Sewage Treatment Plant (STP) to the Peconic River exceeded on five occasions, three for residual chlorine and one each for iron and ammonia nitrogen. The chlorine exceedances were related to a malfunctioning hypochlorite dosing pump and ceased when the pump was repaired. While the iron and ammonia-nitrogen could be the result of disturbances to the sand filter beds during maintenance. The environmental monitoring data has identified site-specific contamination of ground water and soil. These areas are subject to Remedial Investigation/Feasibility Studies (RI/FS) under the Inter Agency Agreement (IAG). Except for the above, the environmental monitoring data has continued to demonstrate that compliance was achieved with applicable environmental laws and regulations governing emission and discharge of materials to the environment, and that the environmental impacts at BNL are minimal and pose no threat to the public or to the environment. This report meets the requirements of DOE Orders 5484. 1, Environmental Protection, Safety, and Health Protection Information reporting requirements and 5400.1, General Environmental Protection Programs.

  4. NATURAL RESOURCE MANAGEMENT PLAN FOR BROOKHAVEN NATIONAL LABORATORY.

    Energy Technology Data Exchange (ETDEWEB)

    GREEN,T.ET AL.

    2003-12-31

    Brookhaven National Laboratory (BNL) is located near the geographic center of Long Island, New York. The Laboratory is situated on 5,265 acres of land composed of Pine Barrens habitat with a central area developed for Laboratory work. In the mid-1990s BNL began developing a wildlife management program. This program was guided by the Wildlife Management Plan (WMP), which was reviewed and approved by various state and federal agencies in September 1999. The WMP primarily addressed concerns with the protection of New York State threatened, endangered, or species of concern, as well as deer populations, invasive species management, and the revegetation of the area surrounding the Relativistic Heavy Ion Collider (RHIC). The WMP provided a strong and sound basis for wildlife management and established a basis for forward motion and the development of this document, the Natural Resource Management Plan (NRMP), which will guide the natural resource management program for BNL. The body of this plan establishes the management goals and actions necessary for managing the natural resources at BNL. The appendices provide specific management requirements for threatened and endangered amphibians and fish (Appendices A and B respectively), lists of actions in tabular format (Appendix C), and regulatory drivers for the Natural Resource Program (Appendix D). The purpose of the Natural Resource Management Plan is to provide management guidance, promote stewardship of the natural resources found at BNL, and to integrate their protection with pursuit of the Laboratory's mission. The philosophy or guiding principles of the NRMP are stewardship, adaptive ecosystem management, compliance, integration with other plans and requirements, and incorporation of community involvement, where applicable.

  5. Brookhaven National Laboratory site environmental report for calendar year 1993

    International Nuclear Information System (INIS)

    This report documents the results of the Environmental Monitoring Program at BNL and presents summary information about environmental compliance for 1993. To evaluate the effect of BNL operations on the local environment, measurements of direct radiation, and a variety of radionuclides and chemical compounds in ambient air, soil, sewage effluent, surface water, ground water and vegetation were made at the BNL site and at sites adjacent to the Laboratory. Brookhaven National Laboratory's compliance with all applicable guides, standards, and limits for radiological and nonradiological emissions to the environment were evaluated. Among the permitted facilities, two instances, of pH exceedances were observed at recharge basins, possible related to rain-water run-off to these recharge basins. Also, the discharge from the Sewage Treatment Plant (STP) to the Peconic River exceeded on five occasions, three for residual chlorine and one each for iron and ammonia nitrogen. The chlorine exceedances were related to a malfunctioning hypochlorite dosing pump and ceased when the pump was repaired. While the iron and ammonia-nitrogen could be the result of disturbances to the sand filter beds during maintenance. The environmental monitoring data has identified site-specific contamination of ground water and soil. These areas are subject to Remedial Investigation/Feasibility Studies (RI/FS) under the Inter Agency Agreement (IAG). Except for the above, the environmental monitoring data has continued to demonstrate that compliance was achieved with applicable environmental laws and regulations governing emission and discharge of materials to the environment, and that the environmental impacts at BNL are minimal and pose no threat to the public or to the environment. This report meets the requirements of DOE Orders 5484. 1, Environmental Protection, Safety, and Health Protection Information reporting requirements and 5400.1, General Environmental Protection Programs

  6. Initial experiments with the Nevis Cyclotron, the Brookhaven Cosmotron, the Brookhaven AGS and their effects on high energy physics

    International Nuclear Information System (INIS)

    The first experiment at the Nevis Cyclotron by Bernardini, Booth and Lindenbaum demonstrated that nuclear stars are produced by a nucleon-nucleon cascade within the nucleon. This solved a long standing problem in Cosmic rays and made it clear that where they overlap cosmic ray investigation would not be competitive with accelerator investigations. The initial experiments at the Brookhaven Cosmotron by Lindenbaum and Yuan demonstrated that low energy pion nucleon scattering and pion production were unexpectedly mostly due to excitation of the isotopic spin = angular momentum = 3/2 isobaric state of the nucleon. This contradicted the Fermi statistical theory and led to the Isobar model proposed by the author and a collaborator. The initial experiments at the AGS by the author and collaborators demonstrated that the Pomeronchuck Theorem would not come true till at least several hundred GeV. These scattering experiments led to the development of the ''On-line Computer Technique'' by the author and collaborators which is now the almost universal technique in high energy physics. The first accomplishment which flowed from this technique led to contradiction of the Regge pole theory as a dynamical asymptotic theory, by the author and collaborators. The first critical experimental proof of the forward dispersion relation in strong interactions was accomplished by the author and collaborators. They were then used as a crystal ball to predict that ''Asymptopia''---the theoretically promised land where all asymptotic theorems come true---would not be reached till at least 25,000 BeV and probably not before 1,000,000 BeV. 26 refs., 11 figs., 2 tabs

  7. Towards an automated virtual slide screening: theoretical considerations and practical experiences of automated tissue-based virtual diagnosis to be implemented in the Internet

    OpenAIRE

    Bzdyl Piotr; Radziszowski Dominik; Kayser Klaus; Sommer Rainer; Kayser Gian

    2006-01-01

    Abstract Aims To develop and implement an automated virtual slide screening system that distinguishes normal histological findings and several tissue – based crude (texture – based) diagnoses. Theoretical considerations Virtual slide technology has to handle and transfer images of GB Bytes in size. The performance of tissue based diagnosis can be separated into a) a sampling procedure to allocate the slide area containing the most significant diagnostic information, and b) the evaluation of t...

  8. Wildland Fire Management Plan for Brookhaven National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Green,T.

    2009-10-23

    This Wildland Fire Management Plan (FMP) for Brookhaven National Lab (BNL) updates the 2003 plan incorporating changes necessary to comply with DOE Order 450.1 and DOE P 450.4, Federal Wildland Fire Management Policy and Program Review; Wildland and Prescribed Fire Management Policy and implementation Procedures Reference Guide. This current plan incorporates changes since the original draft of the FMP that result from new policies on the national level. This update also removes references and dependence on the U.S. Fish & Wildlife Service and Department of the Interior, fully transitioning Wildland Fire Management responsibilities to BNL. The Department of Energy policy for managing wildland fires requires that all areas, managed by the DOE and/or its various contractors, that can sustain fire must have a FMP that details fire management guidelines for operational procedures associated with wild fire, operational, and prescribed fires. Fire management plans provide guidance on fire preparedness, fire prevention, wildfire suppression, and the use of controlled, 'prescribed' fires and mechanical means to control the amount of available combustible material. Values reflected in the BNL Wildland FMP include protecting life and public safety; Lab properties, structures and improvements; cultural and historical sites; neighboring private and public properties; and endangered, threatened, and species of concern. Other values supported by the plan include the enhancement of fire-dependent ecosystems at BNL. This FMP will be reviewed periodically to ensure the fire program advances and evolves with the missions of the DOE and BNL. This Fire Management Plan is presented in a format that coverers all aspects specified by DOE guidance documents which are based on the national template for fire management plans adopted under the National Fire Plan. The DOE is one of the signatory agencies on the National Fire Plan. This FMP is to be used and implemented for the

  9. Natural Resource Management Plan for Brookhaven National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    green, T.

    2011-08-15

    This comprehensive Natural Resource Management Plan (NRMP) for Brookhaven National Laboratory (BNL) was built on the successful foundation of the Wildlife Management Plan for BNL, which it replaces. This update to the 2003 plan continues to build on successes and efforts to better understand the ecosystems and natural resources found on the BNL site. The plan establishes the basis for managing the varied natural resources located on the 5,265 acre BNL site, setting goals and actions to achieve those goals. The planning of this document is based on the knowledge and expertise gained over the past 10 years by the Natural Resources management staff at BNL in concert with local natural resource agencies including the New York State Department of Environmental Conservation, Long Island Pine Barrens Joint Planning and Policy Commission, The Nature Conservancy, and others. The development of this plan is an attempt at sound ecological management that not only benefits BNL's ecosystems but also benefits the greater Pine Barrens habitats in which BNL is situated. This plan applies equally to the Upton Ecological and Research Reserve (Upton Reserve). Any difference in management between the larger BNL area and the Upton Reserve are noted in the text. The purpose of the Natural Resource Management Plan (NRMP) is to provide management guidance, promote stewardship of the natural resources found at BNL, and to sustainably integrate their protection with pursuit of the Laboratory's mission. The philosophy or guiding principles of the NRMP are stewardship, sustainability, adaptive ecosystem management, compliance, integration with other plans and requirements, and the incorporation of community involvement, where applicable. The NRMP is periodically reviewed and updated, typically every five years. This review and update was delayed to develop documents associated with a new third party facility, the Long Island Solar Farm. This two hundred acre facility will result in

  10. Do Workshops in Evidence-Based Practice Equip Participants to Identify and Answer Questions Requiring Consideration of Clinical Research? A Diagnostic Skill Assessment

    Science.gov (United States)

    Wyer, Peter C,; Naqvi, Zoon; Dayan, Peter S.; Celentano, James J.; Eskin, Barnet; Graham, Mark J.

    2009-01-01

    Evidence-based practice (EBP) requires practitioners to identify and formulate questions in response to patient encounters, and to seek, select, and appraise applicable clinical research. A standardized workshop format serves as the model for training of medical educators in these skills. We developed an evaluation exercise to assess the ability…

  11. Professional Game Artists: An investigation into the primary considerations that impact upon their work, and the effects upon their creative practice

    Directory of Open Access Journals (Sweden)

    Ken Fee

    2015-07-01

    Full Text Available This article represents the author’s preliminary research into an area of creative practice that he pursued for some 20 years, namely that of a full time professional computer game artist. Initially collaborating with academics as a part time lecturer and industrial consultant, for the past eight years his roles within academia have focused on developing pedagogical models of professional practice within games education. Through his interaction with students, employers and graduates, the author began to identify an area of keen personal interest – namely, the actual realities of being a professional game artist, and the potential consequences on creative practice. In identifying the constraints and influences that direct such an artist’s work, it is the intention that a broader discussion may then follow, exploring how such artists can protect their creative muse, when the evidence would suggest that many aspects of the games industry are an absolute anathema to individual expression. In addition to his own experiences and research, the author has drawn on interviews with other professionals from games development, as well as artists who work in other areas of professional artistic practice (such as Fine Art, Illustration, and Comics. In this way his intention is to identify the areas of practice common to other areas of art, while highlighting any of the more unique elements present specifically within games development itself. While there is a large body or research into game design principles and technologies, there is very little discussion that focuses on the very people that make them. It is the author’s hope that this article plays some small part in starting to redress this balance, and may help the reader to appreciate the challenges such artists face.

  12. A woman like you: Women scientists and engineers at Brookhaven National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Benkovitz, Carmen; Bernholc, Nicole; Cohen, Anita; Eng, Susan; Enriquez-Leder, Rosario; Franz, Barbara; Gorden, Patricia; Hanson, Louise; Lamble, Geraldine; Martin, Harriet; Mastrangelo, Iris; McLane, Victoria; Villela, Maria-Alicia; Vivirito, Katherine; Woodhead, Avril

    1991-01-01

    This publication by the women in Science and Engineering introduces career possibilities in science and engineering. It introduces what work and home life are like for women who have already entered these fields. Women at Brookhaven National Laboratory work in a variety of challenging research roles -- from biologist and environmental scientist to safety engineer, from patent lawyer to technician. Brookhaven National Laboratory is a multi-program laboratory which carries out basic and applied research in the physical, biomedical and environmental sciences and in selected energy technologies. The Laboratory is managed by Associated University, Inc., under contract with the US Department of Energy. Brookhaven and the other national laboratories, because of their enormous research resources, can play a critical role in a education and training of the workforce.

  13. A woman like you: Women scientists and engineers at Brookhaven National Laboratory. Careers in action

    Energy Technology Data Exchange (ETDEWEB)

    1991-12-31

    This publication by the women in Science and Engineering introduces career possibilities in science and engineering. It introduces what work and home life are like for women who have already entered these fields. Women at Brookhaven National Laboratory work in a variety of challenging research roles -- from biologist and environmental scientist to safety engineer, from patent lawyer to technician. Brookhaven National Laboratory is a multi-program laboratory which carries out basic and applied research in the physical, biomedical and environmental sciences and in selected energy technologies. The Laboratory is managed by Associated University, Inc., under contract with the US Department of Energy. Brookhaven and the other national laboratories, because of their enormous research resources, can play a critical role in a education and training of the workforce.

  14. Technical considerations and problems associated with long-term storage of low-level waste

    International Nuclear Information System (INIS)

    If a state or regional compact does not have adequate disposal capacity for low-level radioactive waste (LLRW), then extended storage of certain LLRW may be necessary. The Nuclear Regulatory Commission (NRC) contracted with Brookhaven National Laboratory (BNL) several years ago (1984--86) to address the technical issues of extended storage. The dual objectives of this study were (1) to provide practical technical assessments for NRC to consider in evaluating specific proposals for extended storage and (2) to help ensure adequate consideration by NRC, Agreement States, and licensees of potential problems that may arise from existing or proposed extended storage practices. In this summary of that study, the circumstances under which extended storage of LLRW would most likely result in problems during or after the extended storage period are considered and possible mitigative measures to minimize these problems are discussed. These potential problem areas include: (1) the degradation of carbon steel and polyethylene containers during storage and the subsequent need for repackaging (resulting in increased occupational exposure), (2) the generation of hazardous gases during storage, and (3) biodegradative processes in LLRW

  15. Best-practices approach to determination of blood alcohol concentration (BAC) at specific time points: Combination of ante-mortem alcohol pharmacokinetic modeling and post-mortem alcohol generation and transport considerations.

    Science.gov (United States)

    Cowan, Dallas M; Maskrey, Joshua R; Fung, Ernest S; Woods, Tyler A; Stabryla, Lisa M; Scott, Paul K; Finley, Brent L

    2016-07-01

    Alcohol concentrations in biological matrices offer information regarding an individual's intoxication level at a given time. In forensic cases, the alcohol concentration in the blood (BAC) at the time of death is sometimes used interchangeably with the BAC measured post-mortem, without consideration for alcohol concentration changes in the body after death. However, post-mortem factors must be taken into account for accurate forensic determination of BAC prior to death to avoid incorrect conclusions. The main objective of this work was to describe best practices for relating ante-mortem and post-mortem alcohol concentrations, using a combination of modeling, empirical data and other qualitative considerations. The Widmark modeling approach is a best practices method for superimposing multiple alcohol doses ingested at various times with alcohol elimination rate adjustments based on individual body factors. We combined the selected ante-mortem model with a suggestion for an approach used to roughly estimate changes in BAC post-mortem, and then analyzed the available data on post-mortem alcohol production in human bodies and potential markers for alcohol production through decomposition and putrefaction. Hypothetical cases provide best practice approaches as an example for determining alcohol concentration in biological matrices ante-mortem, as well as potential issues encountered with quantitative post-mortem approaches. This study provides information for standardizing BAC determination in forensic toxicology, while minimizing real world case uncertainties. PMID:27041394

  16. Molecular Pathology and Personalized Medicine: The Dawn of a New Era in Companion Diagnostics—Practical Considerations about Companion Diagnostics for Non-Small-Cell-Lung-Cancer

    Directory of Open Access Journals (Sweden)

    Till Plönes

    2016-01-01

    Full Text Available Companion diagnostics (CDx have become a major tool in molecular pathology and assist in therapy decisions in an increasing number of various cancers. Particularly, the developments in lung cancer have been most impressing in the last decade and consequently lung cancer mutation testing and molecular profiling has become a major business of diagnostic laboratories. However, it has become difficult to decide which biomarkers are currently relevant for therapy decisions, as many of the new biomarkers are not yet approved as therapy targets, remain in the status of clinical studies, or still have not left the experimental phase. The current review is focussed on those markers that do have current therapy implications, practical implications arising from the respective companion diagnostics, and thus is focused on daily practice.

  17. Aberration-Coreected Electron Microscopy at Brookhaven National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Zhu,Y.; Wall, J.

    2008-04-01

    The last decade witnessed the rapid development and implementation of aberration correction in electron optics, realizing a more-than-70-year-old dream of aberration-free electron microscopy with a spatial resolution below one angstrom [1-9]. With sophisticated aberration correctors, modern electron microscopes now can reveal local structural information unavailable with neutrons and x-rays, such as the local arrangement of atoms, order/disorder, electronic inhomogeneity, bonding states, spin configuration, quantum confinement, and symmetry breaking [10-17]. Aberration correction through multipole-based correctors, as well as the associated improved stability in accelerating voltage, lens supplies, and goniometers in electron microscopes now enables medium-voltage (200-300kV) microscopes to achieve image resolution at or below 0.1nm. Aberration correction not only improves the instrument's spatial resolution but, equally importantly, allows larger objective lens pole-piece gaps to be employed thus realizing the potential of the instrument as a nanoscale property-measurement tool. That is, while retaining high spatial resolution, we can use various sample stages to observe the materials response under various temperature, electric- and magnetic- fields, and atmospheric environments. Such capabilities afford tremendous opportunities to tackle challenging science and technology issues in physics, chemistry, materials science, and biology. The research goal of the electron microscopy group at the Dept. of Condensed Matter Physics and Materials Science and the Center for Functional Nanomaterials, as well as the Institute for Advanced Electron Microscopy, Brookhaven National Laboratory (BNL), is to elucidate the microscopic origin of the physical- and chemical-behavior of materials, and the role of individual, or groups of atoms, especially in their native functional environments. We plan to accomplish this by developing and implementing various quantitative

  18. Practical and clinical considerations in assessing patients with atrial fibrillation for switching to non-vitamin K antagonist oral anticoagulants in primary care

    Directory of Open Access Journals (Sweden)

    Guimarães PO

    2015-09-01

    Full Text Available Patrícia O Guimarães,1 Scott Kaatz,2 Renato D Lopes11Duke Clinical Research Institute, Duke Medicine, Durham, NC, 2Hurley Medical Center, Flint, MI, USAAbstract: Atrial fibrillation (AF is an important risk factor for thromboembolic events, and anticoagulation therapy can reduce this risk. Vitamin K antagonists (VKAs, such as warfarin, have been used for decades in patients with AF for stroke prevention. Currently, non-VKA oral anticoagulants (NOACs are approved and available for non-valvular AF patients who are at increased risk of stroke. These agents are safe and effective and have important advantages over VKAs, such as significant reduction in intracranial hemorrhage and no need for routine laboratory monitoring. Thus, should all VKA-treated patients be switched to a NOAC? The aims of this article are: 1 to review the advantages of NOACs over VKAs; 2 to identify the group of patients who most benefit from receiving a NOAC and, therefore, are higher priority to be switched from VKAs; and 3 to provide clinical and practical guidance on how to switch patients safely from VKAs to NOACs.Keywords: anticoagulation, atrial fibrillation, clinical practice, stroke prevention

  19. Considerations on boron neutron capture therapy

    International Nuclear Information System (INIS)

    This article reviews the radiotherapy technique called Boron Neutron Capture Therapy - BNCT. Herein, basic concepts in BNCT are addressed, particularly how BNCT has been used in the attempts of defeating multiform glioblastoma. The history of the BNCT trials in the 50's and 60's, including the previous trials at Brookhaven National Laboratory (BNL) and at the Massachusetts Institute of Technology (MIT) are presented. The Japanese experience in BNCT is discussed. Recently, clinical trials at the MIT and BNL have started, focusing multiform glioblastoma and peripheral and intracranial melanomas. Radiobiological and clinical data from Phase I trials on MIT are discussed. Considerations in how BNCT can be developed in Brazil are presented. It shows that Cf-252 Brachytherapy coupled with NCT may be a non-expensive, alternative way of addressing BNCT. (author)

  20. Reliability and Efficiency in Shear-Wave Velocity Inversion Methods and Practical Considerations for Multi-Mode Surface Wave Inversion Technique

    Science.gov (United States)

    Hosseini, M.; Pezeshk, S.

    2011-12-01

    Multi-channel Spectral Analysis of Surface Waves (MASW) and the inversion for shear-wave velocity have been quite popular considering the low cost. The MASW method has been widely researched in the last three decades as a non-invasive procedure to determine shear-wave velocity of shallow subsurface. The MASW method can provide results accurate enough to replace the invasive downhole seismic survey which requires a borehole and is more time consuming and will cost more. The MASW method results suffer from inherent non-uniqueness problem. The reduction of such non-uniqueness can greatly improve the accuracy and reliability of inverted profiles. Such improvement can include imposing boundaries and constraints on the range of shear-wave velocity of layers and considering the higher modes of Rayleigh wave propagation and consideration for higher modes is not a simple task. The reliability of the forward method which is used in the inversion process, is one of the crucial items to be evaluated, and there are cases that some forward method algorithms fails to find the roots related to higher modes correctly, and in such cases there will be jumps in dispersion curves to higher modes. The computer environment under which the forward method is being developed is important. In some cases the computational efficiency of the inversion process is completely depended on the computation environment. Furthermore it is important to use a global search technique to try to obtain the global optimum solution instead of local ones. Also, due to the nature of inversion process, there are several parameters which their values affect the results of inverted shear-wave velocity profile such as the initial model, poison ratio, etc. To reduce uncertainties, we need to run the inversion procedure several times considering different parameters which can be quite time consuming and impractical. To overcome such limitations, an algorithm is designed to launch the shear-wave velocity inversion

  1. The neutrino horn 300 kiloampere pulsed power supply at Brookhaven National Laboratory

    International Nuclear Information System (INIS)

    A 300 Kiloampere pulsed power system used to energize the Brookhaven focusing neutrino horn is described. The constant current switching section, coaxial power feed and low level control system are presented. Calculations determining system performance are compared with measured values. Plans for future systems are discussed

  2. Brookhaven Lab physicist William Willis wins the 2003 W.K.H. Panofsky prize

    CERN Multimedia

    2003-01-01

    William Willis, a senior physicist Brookhaven National Laboratory, has won the American Physical Society's 2003 W.K.H. Panofsky Prize in Experimental Particle Physics. He received the prize, which consists of $5,000 and a certificate citing his contributions to physics, at the APS meeting in Philadelphia on April 6 (1 page).

  3. Mechanical support and transport system used for the neutrino horn system at Brookhaven National Laboratory

    International Nuclear Information System (INIS)

    The study of neutrinos at the Alternating Gradient Synchrotron (AGS), Brookhaven National Laboratory (BNL), requires hardware for their initiation and control. The basics consist of a target, two horns and three collimators. This paper describes the installation, support and positioning of these components within a settling concrete blockhouse

  4. Mechanical support and transport system used for the neutrino horn system at Brookhaven National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Walker, J.C.; Carroll, A.S.; Leonhardt, W.; Monaghan, R.; Pearson, C.; Pendzick, A.; Ryan, G.; Sandberg, J.; Sims, W.P.; Smith, G.A.

    1987-01-01

    The study of neutrinos at the Alternating Gradient Synchrotron (AGS), Brookhaven National Laboratory (BNL), requires hardware for their initiation and control. The basics consist of a target, two horns and three collimators. This paper describes the installation, support and positioning of these components within a settling concrete blockhouse.

  5. T.D. LEE: RELATIVISTIC HEAVY ION COLLISIONS AND THE RIKEN BROOKHAVEN CENTER.

    Energy Technology Data Exchange (ETDEWEB)

    MCLERRAN,L.; SAMIOS, N.

    2006-11-24

    This paper presents the history of Professor T. D. Lee's seminal work on the theory of relativistic heavy ion collisions, and the founding and development of the Riken Brookhaven Center. A number of anecdotes are given about Prof. Lee, and his strong positive effect on his colleagues, particularly young physicists.

  6. Data acquisition system for Experiment E866 at the Brookhaven AGS

    International Nuclear Information System (INIS)

    Experiment E866 consists of two spectrometers and related detectors for investigations of collisions of relativistic beams of Au ions with fixed targets at the Brookhaven AGS. The data acquisition system, consisting of 11 CPUs in a single VME crate, gathers data from 8 Camac crates and 6 Fastbus crates

  7. From nuclei to hypernuclei: A retrospective view of medium energy physics at Brookhaven

    International Nuclear Information System (INIS)

    A new frontier in physics originated with programs at two Brookhaven National Laboratory facilities--the Cosmotron and the Alternating Gradient Synchrotron. The development of this frontier over a half century is described, as it turned from conventional nuclear physics to the hypernuclei and the study of strange matter

  8. Brookhaven highlights, fiscal year 1985, October 1, 1984-September 30, 1985

    Energy Technology Data Exchange (ETDEWEB)

    1985-01-01

    Activities at Brookhaven National Laboratory are briefly discussed. These include work at the National Synchrotron Light Source, the High Flux Beam Reactor, and the Alternating Gradient Synchrotron. Areas of research include heavy ion reactions, neutrino oscillations, low-level waste, nuclear data, medicine, biology, chemistry, parallel computing, optics. Also provided are general and administrative news, a financial report. (LEW)

  9. Brookhaven highlights, fiscal year 1985, October 1, 1984-September 30, 1985

    International Nuclear Information System (INIS)

    Activities at Brookhaven National Laboratory are briefly discussed. These include work at the National Synchrotron Light Source, the High Flux Beam Reactor, and the Alternating Gradient Synchrotron. Areas of research include heavy ion reactions, neutrino oscillations, low-level waste, nuclear data, medicine, biology, chemistry, parallel computing, optics. Also provided are general and administrative news, a financial report

  10. Practical Considerations in the Re-Irradiation of Recurrent and Second Primary Head-and-Neck Cancer: Who, Why, How, and How Much?

    International Nuclear Information System (INIS)

    Despite progress in surgical and reconstructive techniques, as well as advances in radiotherapy delivery methods, a significant proportion of patients irradiated for head-and-neck cancer develop locoregional recurrence. These patients are also at high risk of developing new second primary cancers of the head and neck. Because of the heterogeneity of this population with respect to disease-related and patient-related factors, such as previous treatment, tumor recurrence site, disease extent, and performance status, the optimal treatment of locoregionally recurrent or second primary cancers of the head and neck remains to be defined. Although surgical resection typically constitutes the mainstay of treatment, effective salvage therapy is often precluded by anatomic inaccessibility and the risk of perioperative complications. Although chemotherapy alone has traditionally been considered an alternative to surgery, the response rates have been poor, with nearly all patients dying of disease progression within months. Similarly, salvage therapy using re-irradiation has historically been avoided because of concerns regarding toxicity. Although the results of more recent studies using contemporary treatment techniques and conformal delivery methods have been somewhat more promising, the role of re-irradiation after previous full-course radiotherapy is still considered investigational by many. Numerous questions remain unanswered, and practical guidelines for clinical decision-making are sparse.

  11. Current practice in and considerations for personalized medicine in lung cancer: From the patient's molecular biology to patient values and preferences.

    Science.gov (United States)

    Carrera, Pricivel M; Ormond, Meghann

    2015-09-01

    Both at the individual and health system levels, the burden of complex illnesses associated with and which rise in mid- to later life, such as cancer, is expected to increase further. The advent of personalized medicine, or the use of a patient's genetic profile to guide medical decisions, is touted to substantially improve drug tolerance and efficacy and, in so doing, also improve the effectiveness and efficiency of oncological care. Amidst the hype and hope surrounding personalized cancer care, there is increasing concern about its unnecessary, unintended effects especially with regards to the financial burden of targeted therapies using specialty drugs. In this paper, we take a patient-centered perspective on the therapeutic benefits of personalized medicine as well as the limitations of current practice and its psychological and financial toxicities by focusing on advanced-stage lung cancer. We argue that the modest clinical benefits of targeted therapy, premium prices for many specialty drugs and the narrow focus on the genetic constitution of individual patients run the risk of undercutting personalized lung cancer care's contribution to realizing health and non-health outcomes. We discuss the contribution of grading the financial burden of treatment and seamless integration of palliative care as key action areas regarding patients' access to and appropriateness of care given patients' needs and preferences. PMID:25981825

  12. Towards an automated virtual slide screening: theoretical considerations and practical experiences of automated tissue-based virtual diagnosis to be implemented in the Internet

    Directory of Open Access Journals (Sweden)

    Bzdyl Piotr

    2006-06-01

    Full Text Available Abstract Aims To develop and implement an automated virtual slide screening system that distinguishes normal histological findings and several tissue – based crude (texture – based diagnoses. Theoretical considerations Virtual slide technology has to handle and transfer images of GB Bytes in size. The performance of tissue based diagnosis can be separated into a a sampling procedure to allocate the slide area containing the most significant diagnostic information, and b the evaluation of the diagnosis obtained from the information present in the selected area. Nyquist's theorem that is broadly applied in acoustics, can also serve for quality assurance in image information analysis, especially to preset the accuracy of sampling. Texture – based diagnosis can be performed with recursive formulas that do not require a detailed segmentation procedure. The obtained results will then be transferred into a "self-learning" discrimination system that adjusts itself to changes of image parameters such as brightness, shading, or contrast. Methods Non-overlapping compartments of the original virtual slide (image will be chosen at random and according to Nyquist's theorem (predefined error-rate. The compartments will be standardized by local filter operations, and are subject for texture analysis. The texture analysis is performed on the basis of a recursive formula that computes the median gray value and the local noise distribution. The computations will be performed at different magnifications that are adjusted to the most frequently used objectives (*2, *4.5, *10, *20, *40. The obtained data are statistically analyzed in a hierarchical sequence, and in relation to the clinical significance of the diagnosis. Results The system has been tested with a total of 896 lung cancer cases that include the diagnoses groups: cohort (1 normal lung – cancer; cancer subdivided: cohort (2 small cell lung cancer – non small cell lung cancer; non small cell lung

  13. Final environmental impact statement. Proton--Proton Storage Accelerator Facility (ISABELLE), Brookhaven National Laboratory, Upton, New York

    Energy Technology Data Exchange (ETDEWEB)

    Liverman, James L.

    1978-08-01

    An Environmental Impact Statement for a proposed research facility (ISABELLE) to be built at Brookhaven National Laboratory (BNL) is presented. It was prepared by the Department of Energy (DOE) following guidelines issued for such analyses. In keeping with DOE policy, this statement presents a concise and issues-oriented analysis of the significant environmental effects associated with the proposed action. ISABELLE is a proposed physics research facility where beams of protons collide providing opportunities to study high energy interactions. The facility would provide two interlaced storage ring proton accelerators, each with an energy up to 400 GeV intersecting in six experimental areas. The rings are contained in a tunnel with a circumference of 3.8 km (2.3 mi). The facility will occupy 250 ha (625 acres) in the NW corner of the existing BNL site. A draft Environmental Impact Statement for this proposed facility was issued for public review and comment by DOE on February 21, 1978. The principal areas of concern expressed were in the areas of radiological impacts and preservation of cultural values. After consideration of these comments, appropriate actions were taken and the text of the statement has been amended to reflect the comments. The text was annotated to indicate the origin of the comment. The Appendices contain a glossary of terms and listings of metric prefixes and conversions and symbols and abbreviations.

  14. Final environmental impact statement. Proton--Proton Storage Accelerator Facility (ISABELLE), Brookhaven National Laboratory, Upton, New York

    International Nuclear Information System (INIS)

    An Environmental Impact Statement for a proposed research facility (ISABELLE) to be built at Brookhaven National Laboratory (BNL) is presented. It was prepared by the Department of Energy (DOE) following guidelines issued for such analyses. In keeping with DOE policy, this statement presents a concise and issues-oriented analysis of the significant environmental effects associated with the proposed action. ISABELLE is a proposed physics research facility where beams of protons collide providing opportunities to study high energy interactions. The facility would provide two interlaced storage ring proton accelerators, each with an energy up to 400 GeV intersecting in six experimental areas. The rings are contained in a tunnel with a circumference of 3.8 km (2.3 mi). The facility will occupy 250 ha (625 acres) in the NW corner of the existing BNL site. A draft Environmental Impact Statement for this proposed facility was issued for public review and comment by DOE on February 21, 1978. The principal areas of concern expressed were in the areas of radiological impacts and preservation of cultural values. After consideration of these comments, appropriate actions were taken and the text of the statement has been amended to reflect the comments. The text was annotated to indicate the origin of the comment. The Appendices contain a glossary of terms and listings of metric prefixes and conversions and symbols and abbreviations

  15. Lessons Learned from the Application of Bulk Characterization to Individual Containers on the Brookhaven Graphite Research Reactor Decommissioning Project at Brookhaven National Laboratory - 12056

    International Nuclear Information System (INIS)

    When conducting environmental cleanup or decommissioning projects, characterization of the material to be removed is often performed when the material is in-situ. The actual demolition or excavation and removal of the material can result in individual containers that vary significantly from the original bulk characterization profile. This variance, if not detected, can result in individual containers exceeding Department of Transportation regulations or waste disposal site acceptance criteria. Bulk waste characterization processes were performed to initially characterize the Brookhaven Graphite Research Reactor (BGRR) graphite pile and this information was utilized to characterize all of the containers of graphite. When the last waste container was generated containing graphite dust from the bottom of the pile, but no solid graphite blocks, the material contents were significantly different in composition from the bulk waste characterization. This error resulted in exceedance of the disposal site waste acceptance criteria. Brookhaven Science Associates initiated an in-depth investigation to identify the root causes of this failure and to develop appropriate corrective actions. The lessons learned at BNL have applicability to other cleanup and demolition projects which characterize their wastes in bulk or in-situ and then extend that characterization to individual containers. (authors)

  16. Lessons Learned from the Application of Bulk Characterization to Individual Containers on the Brookhaven Graphite Research Reactor Decommissioning Project at Brookhaven National Laboratory - 12056

    Energy Technology Data Exchange (ETDEWEB)

    Kneitel, Terri [US DOE, Brookhaven Site Office (United States); Rocco, Diane [Brookhaven National Laboratory (United States)

    2012-07-01

    When conducting environmental cleanup or decommissioning projects, characterization of the material to be removed is often performed when the material is in-situ. The actual demolition or excavation and removal of the material can result in individual containers that vary significantly from the original bulk characterization profile. This variance, if not detected, can result in individual containers exceeding Department of Transportation regulations or waste disposal site acceptance criteria. Bulk waste characterization processes were performed to initially characterize the Brookhaven Graphite Research Reactor (BGRR) graphite pile and this information was utilized to characterize all of the containers of graphite. When the last waste container was generated containing graphite dust from the bottom of the pile, but no solid graphite blocks, the material contents were significantly different in composition from the bulk waste characterization. This error resulted in exceedance of the disposal site waste acceptance criteria. Brookhaven Science Associates initiated an in-depth investigation to identify the root causes of this failure and to develop appropriate corrective actions. The lessons learned at BNL have applicability to other cleanup and demolition projects which characterize their wastes in bulk or in-situ and then extend that characterization to individual containers. (authors)

  17. A neutronic feasibility study for LEU conversion of the Brookhaven Medical Research Reactor (BMRR)

    International Nuclear Information System (INIS)

    A neutronic feasibility study for converting the Brookhaven Medical Research Reactor from HEU to LEU fuel was performed at Argonne National Laboratory in cooperation with Brookhaven National Laboratory. Two possible LEU cores were identified that would provide nearly the same neutron flux and spectrum as the present HEU core at irradiation facilities that are used for Boron Neutron Capture Therapy and for animal research. One core has 17 and the other has 18 LEU MTR-type fuel assemblies with uranium densities of 2.5g U/cm3 or less in the fuel meat. This LEU fuel is fully-qualified for routine use. Thermal hydraulics and safety analyses need to be performed to complete the feasibility study. (author)

  18. 2003 Brookhaven National Laboratory Annual Illness and Injury Surveillance Report, Revised September 2007

    Energy Technology Data Exchange (ETDEWEB)

    U.S. Department of Energy, Office of Health, Safety and Security, Office of Illness and Injury Prevention Programs

    2007-10-02

    Annual Illness and Injury Surveillance Program report for 2003 for Brookhaven National Lab. The U.S. Department of Energy’s (DOE) commitment to assuring the health and safety of its workers includes the conduct of epidemiologic surveillance activities that provide an early warning system for health problems among workers. The IISP monitors illnesses and health conditions that result in an absence of workdays, occupational injuries and illnesses, and disabilities and deaths among current workers.

  19. Brookhaven highlights. Report on research, October 1, 1992--September 30, 1993

    Energy Technology Data Exchange (ETDEWEB)

    Rowe, M.S.; Belford, M.; Cohen, A.; Greenberg, D.; Seubert, L. [eds.

    1993-12-31

    This report highlights the research activities of Brookhaven National Laboratory during the period dating from October 1, 1992 through September 30, 1993. There are contributions to the report from different programs and departments within the laboratory. These include technology transfer, RHIC, Alternating Gradient Synchrotron, physics, biology, national synchrotron light source, applied science, medical science, advanced technology, chemistry, reactor physics, safety and environmental protection, instrumentation, and computing and communications.

  20. Ocular radioimmunoscintigraphy: sensitivity and practical considerations

    International Nuclear Information System (INIS)

    Ocular radioimmunoscintigraphy was performed in 20 patients using /sup 99m/Tc-labeled monoclonal antibody 225.28S, F(ab')2 fragments. Radioimmunoscintigraphy was positive in 13 patients and the diagnosis of ocular melanoma was confirmed by enucleation of the eye or clinical follow-up. Scintigraphy was positive in one patient with lymph node metastasis from an ocular melanoma. In six patients immunoscintigraphy was negative. Using this technique a sensitivity of 92.8% was achieved for detecting ocular melanomas. Single photon emission tomography helped to separate the lesions situated in the nasal quadrant of the eye from the adjacent nasopharyngeal activity. With appropriate imaging techniques small tumors of the order of 3 x 5 x 3 mm could be detected clearly

  1. Practical Considerations for Occupational Exposure to NORM

    International Nuclear Information System (INIS)

    In recent years, industries in the UK have greatly improved their awareness of radiological protection issues associated with the use of Naturally Occurring Radioactive Materials (NORM). However, there is still a need to provide clear guidance to industries to enable them to carry out accurate dose estimates on employees and discharge their duties under the UK Ionising Radiations Regulations 1999 (IRR99). This poster focuses on the radiological protection issues associated with the inhalation of dusts in the zircon processing industry where, to date, dose calculations have been based on assumptions about particle sizes, and the lung solubility and activity of radionuclides present in the zircon dusts. The main aim of the work was to collect and analyse real data from the workplace environment to enable more robust dose calculations to be undertaken. During the project five different zircon processing companies were visited. At each site, samples were collected from different stages of the processes being undertaken. The following sample types were collected: bulk dust samples for radionuclide activity and solubility analysis; dust in air samples to determine atmospheric dust loading; inertial impactor samples to determine the particle size distributions of the atmospheric dust. The bulk dust sample analyses demonstrate U-238 activities in the range 2.32 Bq/g to 3.35 Bq/g and Th-232 activities in the range 0.42 Bq/g to 0.74 Bq/g. These are within the ranges reported in the literature. Solubilities of U-238 and Th-232 are all less than 0.004, and would therefore be considered to be 'slow' by the ICRP. The inertial impactor results showed variability in particle size of dusts depending on the process being monitored. When deciding on a particle size for dose assessments, provenance of the dust can guide the assessor towards the most suitable value. In general, an appropriate particle size for use in dose assessments would be one falling within the 2.5-10μm range. When a mechanical process is under study, the most suitable particle size value may in the range 1-2.5 μm, although more aggressive mechanical processes generate dust with distributions in the 2.5-10μm range. Based on the measured parameters for the actual inhalation scenarios, Committed Effective Doses have been found to be well below 1mSv per year for a worker exposed to zircon based products, the trigger point for the application of IRR99. (Author) 22 refs

  2. Practical considerations for pointing a binocular telescope

    Science.gov (United States)

    De La Peña, Michele D.; Terrett, David L.; Thompson, David; Biddick, Christopher J.

    2010-07-01

    The Large Binocular Telescope (LBT) consists of two 8.4-meter primary mirrors on a common mount. When the telescope is complete, to complement the two primaries there will be two 0.9-meter adaptive secondaries and two tertiary mirror flats that all work to support a variety of Gregorian focal stations, as well as prime focus. A fundamental goal of the telescope is to perform interferometric observations, and therefore, there is a critical need for the ability to co-point the individual telescopes to high precision. Further, a unique aspect of the LBT is the comparatively large range over which the optics can be adjusted which provides flexibility for the acquisition of targets. In the most general case, an observer could be performing an observation using different targets, within constraints, with different instruments on each of the two telescope sides, with different observing duty cycles. As a consequence of the binocular nature of the telescope and the number of possible observing combinations, there are unique requirements imposed on the Telescope Control System (TCS), and in particular, on the Pointing Control Subsystem (PCS). It is the responsibility of the PCS to arbitrate the pointing requests made on the two sides of the telescope by the observers, incorporate guide updates, and generate tracking trajectories for the mount and the rotators, in conjunction with providing tip/tilt demands on the subsystem controlling the optical elements, and ensure each target remains on the specified location (i.e., pointing origin) in the focal plane during an active observation. This paper describes the current design and implementation of the LBT PCS.

  3. Practical considerations in ultrasonic wall thickness measurement

    International Nuclear Information System (INIS)

    Ultrasonic inspection is widely used by industry for the detection of corrosion and the measurement of material wall thickness. Due to wall thinning and the various forms of corrosion that can be found in pressure piping and pressure vessels the annual cost of corrosion damage and related service failures, is very expensive. The author interest is primarily in the examination of personnel who need to become competent and certificated in the various skills that are required to carry out wall thickness measurement and detection of wall thinning due to corrosion. The various techniques and equipment available for ultrasonic wall thickness measurement and assessment give rise to problems regarding the accuracy of results and detection of corrosion. This paper will discuss some of the corrosion conditions that may occur and also problems that may arise during wall thickness measurement. Methods of improving the wall thickness measurement and the assessment process will also be discussed. (author)

  4. Theoretical and practical considerations on Kyoto Protocol

    International Nuclear Information System (INIS)

    This paper deals with principles, open issues and economic attractiveness of CDM and Jl. In the first part, some reflections about additionality, baseline criteria and problems that can arise in implementing CDM and JI projects are carried out. In the second part, with reference to a CDM project, some simulations are performed in order to clarify its economic results and understand the role that different variables can play

  5. Practical considerations for service station remediation

    International Nuclear Information System (INIS)

    Oil Company is a phrase with many connotations and denotations. When the words oil industry are used, thought of dragons and multiheaded monsters are brought to mind, and when someone takes on the oil industry, he is thought of as a David trying to slay Goliath. For the purpose of this paper, however, an Oil Company will be looked at as individuals rather than as an entity; furthermore, we are going to categorize oil companies into types. The purpose of this paper is to bring about an increasing sensitivity and awareness of the complex structure of the oil company. The end result that the author is hopping to achieve is to make the legislators and remediators look at service station remediation in new ways

  6. Direct Comparison of Brookhaven Reflectivity Measurements with Free-Electron Theory

    Energy Technology Data Exchange (ETDEWEB)

    Bane, Karl L.F.

    2010-12-13

    The reflectivity at normal incidence of copper and aluminum samples was recently measured over a large frequency range at Brookhaven by one of us (JT). Then using the Kramers-Kroning integrals, and assuming the free-electron model of conductivity, the dependence of conductivity on frequency was obtained. The results seemed to suggest, for example, that the dc conductivities of the copper and evaporated aluminum samples are a factor of 3 lower than expected. We propose in this report, instead, directly fitting the free-electron model to the low frequency end of the reflectivity data. This fitting does not depend on the higher frequency results and on Kramers-Kronig integrations, but it does assume that the data at the low frequency end is sufficiently accurate. Note that for our LCLS wakefield studies, it is only over these (relatively) low frequencies that we need to know the electrical properties of the metals. The equations that relate reflectivity R with the free electron parameters dc conductivity {sigma} and relaxation time {tau} are: (1) {tilde {sigma}} = {sigma}/1-ikc{tau}; (2) {tilde n} = {radical} {tilde {epsilon}} = {radical}(1+4{pi}i{tilde k}c/{omega}); and (3) R = |{tilde n}-1/{tilde n} + 1|{sup 2}. The parameters are ac conductivity {tilde {sigma}}, index of refraction {tilde n}, dielectric constant {tilde {epsilon}}, and wave number k = {omega}/c, with {omega} frequency and c the speed of light. In Fig. 1 we show the ideal behavior of R for a reasonably good conducting metal, where {sigma} = 0.12 x 10{sup 17}/s and {tau} = 0.55 x 10{sup -14} s (solid line); these parameters are, respectively, 2% ({sigma}) and 20% ({tau}) of the nominal values for copper. The parameters were chosen so that the important features of R(k) could be seen easily in one plot. We see 3 distinct regions: (1) for low frequencies, k {approx}< 1/c{tau}, R continually decreases, with positive curvature, and with a low frequency asymptote of (1 - {radical}2kc/{pi}{sigma}); (2) for

  7. Corrosion analysis of decommissioned carbon steel waste water tanks at Brookhaven National Laboratory

    International Nuclear Information System (INIS)

    A corrosion analysis was carried out on available sections of carbon steels taken from two decommissioned radioactive waste water tanks at Brookhaven National Laboratory. One of the 100,000 gallon tanks suffered from a pinhole failure in the wall which was subsequently patched. From the analysis it was shown that this leak, and two adjacent leaks were initiated by a discarded copper heating coil that had been dropped into the tank during service. The failure mechanism is postulated to have been galvanic attack at points of contact between the tank structure and the coil. Other leaks in the two tanks are also described in this report

  8. Status of the visible Free-Electron Laser at the Brookhaven Accelerator Test Facility

    International Nuclear Information System (INIS)

    The 500 nm Free-Electron Laser (ATF) of the Brookhaven National Laboratory is reviewed. We present an overview of the ATF, a high-brightness, 50-MeV, electron accelerator and laser complex which is a users' facility for accelerator and beam physics. A number of laser acceleration and FEL experiments are under construction at the ATF. The visible FEL experiment is based on a novel superferric 8.8 mm period undulator. The electron beam parameters, the undulator, the optical resonator, optical and electron beam diagnostics are discussed. The operational status of the experiment is presented. 22 refs., 7 figs

  9. Superconducting magnet program for X-Ray Lithography source at Brookhaven National Laboratory

    International Nuclear Information System (INIS)

    Brookhaven National Laboratory is funded by DOD-DARPA to develop a compact electron storage ring to be used as a X-Ray source for producing high density computer chips. The circumference of this machine is 8.5 meters, the machine lattice consists of four quadrupoles, two sextupoles and a pair of air-core combined function 3.87 Tesla superconducting dipoles. BNL is developing the superconducting dipoles in collaboration with its industrial partners GDSSD and GSED. This paper will describe the field characteristics and engineering realization of these magnets and present the current status of the program

  10. Risk-based priority scoring for Brookhaven National Laboratory environmental restoration programs

    International Nuclear Information System (INIS)

    This report describes the process of estimating the risk associated with environmental restoration programs under the Brookhaven National Laboratory Office of Environmental Restoration. The process was part of an effort across all Department of Energy facilities to provide a consistent framework to communicate risk information about the facilities to senior managers in the DOE Office of Environmental Management to foster understanding of risk activities across programs. the risk evaluation was a qualitative exercise. Categories considered included: Public health and safety; site personnel safety and health; compliance; mission impact; cost-effective risk management; environmental protection; inherent worker risk; environmental effects of clean-up; and social, cultural, political, and economic impacts

  11. Assessment of Energy Efficiency Project Financing Alternatives for Brookhaven National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Hunt, W. D.; Hail, John C.; Sullivan, Gregory P.

    2000-02-14

    This document provides findings and recommendations that resulted from an assessment of the Brookhaven National Laboratory by a team from Pacific Northwest National Laboratory to assess the site's potential for various alternative financing options as a means to implement energy-efficiency improvements. The assessment looked for life-cycle cost-effective energy-efficiency improvement opportunities, and through a series of staff interviews, evaluated the various methods by which these opportunities may be financed, while considering availability of funds, staff, and available financing options. This report summarizes the findings of the visit and the resulting recommendations.

  12. Corrosion analysis of decommissioned carbon steel waste water tanks at Brookhaven National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Soo, P.; Roberts, T.C.

    1995-07-01

    A corrosion analysis was carried out on available sections of carbon steels taken from two decommissioned radioactive waste water tanks at Brookhaven National Laboratory. One of the 100,000 gallon tanks suffered from a pinhole failure in the wall which was subsequently patched. From the analysis it was shown that this leak, and two adjacent leaks were initiated by a discarded copper heating coil that had been dropped into the tank during service. The failure mechanism is postulated to have been galvanic attack at points of contact between the tank structure and the coil. Other leaks in the two tanks are also described in this report.

  13. Summary of proposed approach for deriving cleanup guidelines for radionuclides in soil at Brookhaven National Laboratory

    International Nuclear Information System (INIS)

    Past activities at Brookhaven National Laboratory (BNL) resulted in soil and groundwater contamination. As a result, BNL was designated a Superfund site under the Comprehensive Environmental Response Compensation and Liability Act (CERCLA). BNL's Office of Environmental Restoration (OER) is overseeing environmental restoration activities at the Laboratory, carried out under an Interagency Agreement (IAG) with the United States Department of Energy (DOE), the United States Environmental Protection Agency (EPA) and the New York State Department of Environmental Conservation (NYSDEC). The objective of this paper is to propose a standard approach to deriving risk-based cleanup guidelines for radionuclides in soil at BNL

  14. Summary of proposed approach for deriving cleanup guidelines for radionuclides in soil at Brookhaven National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Meinhold, A.F.; Morris, S.C.; Dionne, B.; Moskowitz, P.D.

    1996-11-01

    Past activities at Brookhaven National Laboratory (BNL) resulted in soil and groundwater contamination. As a result, BNL was designated a Superfund site under the Comprehensive Environmental Response Compensation and Liability Act (CERCLA). BNL`s Office of Environmental Restoration (OER) is overseeing environmental restoration activities at the Laboratory, carried out under an Interagency Agreement (IAG) with the United States Department of Energy (DOE), the United States Environmental Protection Agency (EPA) and the New York State Department of Environmental Conservation (NYSDEC). The objective of this paper is to propose a standard approach to deriving risk-based cleanup guidelines for radionuclides in soil at BNL.

  15. Job and Task Analysis project at Brookhaven National Laboratory's high flux beam reactor

    International Nuclear Information System (INIS)

    The presenter discussed the Job and Task Analysis (JTA) project conducted at Brookhaven National Laboratory's High Flux Beam Reactor (HFBR). The project's goal was to provide JTA guidelines for use by DOE contractors, then, using the guidelines conduct a JTA for the reactor operator and supervisor positions at the HFBR. Details of the job analysis and job description preparation as well as details of the task selection and task analysis were given. Post JTA improvements to the HFBR training programs were covered. The presentation concluded with a listing of the costs and impacts of the project

  16. Applications of nuclear techniques for in vivo body composition studies at Brookhaven National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Cohn, S.H.; Ellis, K.J.; Vartsky, D.; Vaswani, A.N.; Wielopolski, L.

    1981-01-01

    A series of technical developments and their clinical applications in various nuclear technologies at Brookhaven National Laboratory is described. These include the development of a portable neutron activation facility for measuring cadmium in vivo in kidney and liver, a technique for the measurement of body iron utilizing nuclear resonant scattering of gamma rays, a non-invasive measure of the skeletal levels of lead by an x-ray fluorescence technique, and the development of a pulsed Van de Graaff generator as a source of pulsed neutrons for the measurement of lung silicon. (ACR)

  17. Applications of nuclear techniques for in vivo body composition studies at Brookhaven National Laboratory

    International Nuclear Information System (INIS)

    A series of technical developments and their clinical applications in various nuclear technologies at Brookhaven National Laboratory is described. These include the development of a portable neutron activation facility for measuring cadmium in vivo in kidney and liver, a technique for the measurement of body iron utilizing nuclear resonant scattering of gamma rays, a non-invasive measure of the skeletal levels of lead by an x-ray fluorescence technique, and the development of a pulsed Van de Graaff generator as a source of pulsed neutrons for the measurement of lung silicon

  18. X-ray holographic microscopy experiments at the Brookhaven synchrotron light source

    International Nuclear Information System (INIS)

    Soft x-ray holographic microscopy is discussed from an experimental point of view. Three series of measurements have been carried out using the Brookhaven 750 MeV storage ring as an x-ray source. Young slits fringes, Gabor (in line) holograms and various data pertaining to the soft x-ray performance of photographic plates are reported. The measurements are discussed in terms of the technique for recording them and the experimental limitations in effect. Some discussion is also given of the issues involved in reconstruction using visible light

  19. X-ray holographic microscopy experiments at the Brookhaven Synchrotron Light Source

    International Nuclear Information System (INIS)

    Soft X-ray holographic microscopy is discussed from an experimental point of view. Three series of measurements have been carried out using the Brookhaven 750 MeV storage ring as an X-ray source. Young slits fringes, Gabor (in line) holograms and various data pertaining to the soft x-ray performance of photographic plates are reported. The measurements are discussed in terms of the technique for recording them and the experimental limitations in effect. Some discussion is also given of the issues involved in reconstruction using visible light

  20. X-ray holographic microscopy experiments at the Brookhaven synchrotron light source

    International Nuclear Information System (INIS)

    Soft x-ray holographic microscopy is discussed from an experimental point of view. Three series of measurements have been carried out using the Brookhaven 750 MeV storage ring as an x-ray source. Young slits fringes, Gabor (in line) holograms and various data measurements are discussed in terms of the technique for recording them and the experimental limitations in effect. Some discussion is also given of the issues involved in reconstruction using visible light. 19 references, 12 figures, 1 table

  1. Laser ion source with solenoid for Brookhaven National Laboratory-electron beam ion sourcea)

    Science.gov (United States)

    Kondo, K.; Yamamoto, T.; Sekine, M.; Okamura, M.

    2012-02-01

    The electron beam ion source (EBIS) preinjector at Brookhaven National Laboratory (BNL) is a new heavy ion-preinjector for relativistic heavy ion collider (RHIC) and NASA Space Radiation Laboratory (NSRL). Laser ion source (LIS) is a primary ion source provider for the BNL-EBIS. LIS with solenoid at the plasma drift section can realize the low peak current (˜100 μA) with high charge (˜10 nC) which is the BNL-EBIS requirement. The gap between two solenoids does not cause serious plasma current decay, which helps us to make up the BNL-EBIS beamline.

  2. Laser ion source with solenoid for Brookhaven National Laboratory-electron beam ion source

    International Nuclear Information System (INIS)

    The electron beam ion source (EBIS) preinjector at Brookhaven National Laboratory (BNL) is a new heavy ion-preinjector for relativistic heavy ion collider (RHIC) and NASA Space Radiation Laboratory (NSRL). Laser ion source (LIS) is a primary ion source provider for the BNL-EBIS. LIS with solenoid at the plasma drift section can realize the low peak current (∼100 μA) with high charge (∼10 nC) which is the BNL-EBIS requirement. The gap between two solenoids does not cause serious plasma current decay, which helps us to make up the BNL-EBIS beamline.

  3. Laser ion source with solenoid for Brookhaven National Laboratory-electron beam ion source.

    Science.gov (United States)

    Kondo, K; Yamamoto, T; Sekine, M; Okamura, M

    2012-02-01

    The electron beam ion source (EBIS) preinjector at Brookhaven National Laboratory (BNL) is a new heavy ion-preinjector for relativistic heavy ion collider (RHIC) and NASA Space Radiation Laboratory (NSRL). Laser ion source (LIS) is a primary ion source provider for the BNL-EBIS. LIS with solenoid at the plasma drift section can realize the low peak current (∼100 μA) with high charge (∼10 nC) which is the BNL-EBIS requirement. The gap between two solenoids does not cause serious plasma current decay, which helps us to make up the BNL-EBIS beamline. PMID:22380298

  4. Doing More with Less: Cost-effective, Compact Particle Accelerators (489th Brookhaven Lecture)

    Energy Technology Data Exchange (ETDEWEB)

    Trbojevic, Dejan [BNL Collider-Accelerator Department

    2013-10-22

    Replace a 135-ton magnet used for cancer-fighting particle therapies with a magnet that weighs only two tons? Such a swap is becoming possible thanks to new particle accelerator advances being developed by researchers at Brookhaven Lab. With an approach that combines techniques used by synchrotron accelerators with the ability to accept more energy, these new technologies could be used for more than fighting cancer. They could also decrease the lifecycle of byproducts from nuclear power plants and reduce costs for eRHIC—a proposed electron-ion collider for Brookhaven Lab that researchers from around the world would use to explore the glue that holds together the universe’s most basic building blocks and explore the proton-spin puzzle. During this lecture, Dr. Trbojevic provides an overview of accelerator technologies and techniques—particularly a non-scaling, fixed-focused alternating gradient—to focus particle beams using fewer, smaller magnets. He discusses how these technologies will benefit eRHIC and other applications, including particle therapies being developed to combat cancer.

  5. Manipulating Light to Understand and Improve Solar Cells (494th Brookhaven Lecture)

    Energy Technology Data Exchange (ETDEWEB)

    Eisaman, Matthew [BNL, Sustainable Energy Technologies Department

    2014-04-16

    Energy consumption around the world is projected to approximately triple by the end of the century, according to the 2005 Report from the U.S. Department of Energy's Basic Energy Sciences Workshop on Solar Energy Utilization. Much will change in those next 86 years, but for all the power the world needs—for everything from manufacturing and transportation to air conditioning and charging cell phone batteries—improved solar cells will be crucial to meet this future energy demand with renewable energy sources. At Brookhaven Lab, scientists are probing solar cells and exploring variations within the cells—variations that are so small they are measured in billionths of a meter—in order to make increasingly efficient solar cells and ultimately help reduce the overall costs of deploying solar power plants. Dr. Eisaman will discuss DOE's Sunshot Initiative, which aims to reduce the cost of solar cell-generated electricity by 2020. He will also discuss how he and collaborators at Brookhaven Lab are probing different material compositions within solar cells, measuring how efficiently they collect electrical charge, helping to develop a new class of solar cells, and improving solar-cell manufacturing processes.

  6. Spectral characterization of the epithermal-neutron beam at the Brookhaven medical research reactor

    International Nuclear Information System (INIS)

    The power burst facility boron neutron capture therapy (PBF/BNCT) program schedule required the use of an epithermal-neutron beam before the PBF would be available. The beam was needed to carry out the acute, dose-tolerance study on healthy canines and the treatment protocol on spontaneous tumor canines. Calculations on available U.S. test reactors confirmed that the Brookhaven medical research reactor (BMRR) would be capable of providing an epithermal-neutron beam with sufficient intensity while limiting the fast-neutron and gamma dose contamination to acceptable levels for the canine irradiation studies. A joint Idaho National Engineering Laboratory (INEL)/Brookhaven National Laboratory (BNL) program was instituted to design, construct, install, and measure the performance of an epithermal-neutron beam filter for the BMRR. Aluminum oxide was selected as the filter material because it provided the desired neutron spectrum characteristics given the physical constraints of the available BMRR irradiation beam port. Neutron spectrum measurements of the exit beam were undertaken by INEL as a means to evaluate the performance of the new filter and the validity of neutron transport calculations. The preliminary data from activation measurements were presented at the Neutron Beam Design Workshop at Massachusetts Institute of Technology (MIT) in March 1989. The updated activation results and the proton-recoil measurements are presented in this paper and are compared with predictions derived from a two-dimensional transport calculation

  7. Is Overeating Behavior Similar to Drug Addiction? (427th Brookhaven Lecture)

    International Nuclear Information System (INIS)

    The increasing number of obese individuals in the U.S. and other countries world-wide adds urgency to the need to understand the mechanisms underlying pathological overeating. Research by the speaker and others at Brookhaven National Laboratory and elsewhere is compiling evidence that the brain circuits disrupted in obesity are similar to those involved in drug addiction. Using positron emission tomography (PET), the speaker and his colleagues have implicated brain dopamine in the normal and the pathological intake of food by humans. During the 427th Brookhaven Lecture, speaker will review the findings and implications of PET studies of obese subjects and then compare them to PET research involving drug-addicted individuals. For example, in pathologically obese subjects, it was found that reductions in striatal dopamine D2 receptors are similar to those observed in drug-addicted subjects. The speaker and his colleagues have postulated that decreased levels of dopamine receptors predisposed subjects to search for strongly rewarding reinforcers, be it drugs for the drug-addicted or food for the obese, as a means to compensate for decreased sensitivity of their dopamine-regulated reward circuits. As the speaker will summarize, multiple but similar brain circuits involved in reward, motivation, learning and inhibitory control are disrupted both in drug addiction and obesity, resulting in the need for a multimodal approach to the treatment of obesity.

  8. Is Overeating Behavior Similar to Drug Addiction? (427th Brookhaven Lecture)

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Gene-Jack

    2007-09-27

    The increasing number of obese individuals in the U.S. and other countries world-wide adds urgency to the need to understand the mechanisms underlying pathological overeating. Research by the speaker and others at Brookhaven National Laboratory and elsewhere is compiling evidence that the brain circuits disrupted in obesity are similar to those involved in drug addiction. Using positron emission tomography (PET), the speaker and his colleagues have implicated brain dopamine in the normal and the pathological intake of food by humans. During the 427th Brookhaven Lecture, speaker will review the findings and implications of PET studies of obese subjects and then compare them to PET research involving drug-addicted individuals. For example, in pathologically obese subjects, it was found that reductions in striatal dopamine D2 receptors are similar to those observed in drug-addicted subjects. The speaker and his colleagues have postulated that decreased levels of dopamine receptors predisposed subjects to search for strongly rewarding reinforcers, be it drugs for the drug-addicted or food for the obese, as a means to compensate for decreased sensitivity of their dopamine-regulated reward circuits. As the speaker will summarize, multiple but similar brain circuits involved in reward, motivation, learning and inhibitory control are disrupted both in drug addiction and obesity, resulting in the need for a multimodal approach to the treatment of obesity.

  9. 非侵入性产前检测技术在产前唐氏检测中的伦理思辨%Ethical considerations of non-invasive prenatal testing in Down syndrome prenatal clinical practice

    Institute of Scientific and Technical Information of China (English)

    周萍; 许艳; 明坚; 黄葭燕; 陈英耀

    2015-01-01

    The emerging technique with noninvasive prenatal testing(NIPT) using cell-free fetal deoxyribonucleic acid(DNA) and ribonucleic acid(RNA) in maternal peripheral blood has been reported to be greatly promising for trisomy 21. It has attracted much attention because of its high precision,early and safe testing for the abnormality. However,it has also caused a series of ethical debates and health policy challenges. Through reviewing and analyzing on domestic and international literature and documents,this paper summarized the relative ethical considerations of NIPT in Down’s prenatal clinical practice.%目前,利用孕妇外周血中游离胎儿的脱氧核糖核酸(DNA)、核糖核酸(RNA)测序的非侵入性产前检测技术(non-invasive prenatal testing,NIPT)成为唐氏产前检测中极具应用前景的新兴技术,由于它具有精度高、孕早期即可实施、安全等特性,而备受关注。然而,这项技术也同样引起了一系列伦理争论与卫生政策挑战。文章通过国内外相关文献文件分析,对该技术可能引发的伦理问题进行梳理与总结。

  10. Commissioning of the EBIS-based heavy ion preinjector at Brookhaven

    Energy Technology Data Exchange (ETDEWEB)

    Alessi, J.; Beebe, E.; Binello, S.; Hoff, L.; Kondo, K.; Lambiase, R.; LoDestro, V.; Mapes, M.; McNerney, A.; Morris, J.; Okamura, M.; Pikin, A.I.; Raparia, D.; Ritter, J.; Smart, L.; Snydstrup, L.; Wilinski, M.; Zaltsman, A.; Schempp, A.; Ratzinger, U.; Kanesue, T.

    2010-09-12

    The status is presented of the commissioning of a new heavy ion preinjector at Brookhaven National Laboratory. This preinjector uses an Electron Beam Ion Source (EBIS), and an RFQ and IH Linac, both operating at 100.625 MHz, to produce 2 MeV/u ions of any species for use, after further acceleration, at the Relativistic Heavy Ion Collider (RHIC) and the NASA Space Radiation Laboratory (NSRL). Among the increased capabilities provided by this preinjector are the ability to produce ions of any species, and the ability to switch between multiple species in 1 second, to simultaneously meet the needs of both science programs. For initial setup, helium beam from EBIS was injected and circulated in the Booster synchrotron. Following this, accelerated Au{sup 32+} and Fe{sup 20+} beams were transported to the Booster injection point, fulfilling DOE requirements for project completion.

  11. Antineutrino oscillation study in the muon antineutrino → electron antineutrino channel at the Brookhaven accelerator

    International Nuclear Information System (INIS)

    This thesis is devoted to the E816 experiment which looked for (anti)neutrino oscillations. This experiment was performed in the neutrino beam of the Brookhaven AGS during spring 1986. Following a short recall of the theoretical and experimental status, the beam line and the apparatus are described. The analysis is exposed in details with a special emphasis on final states including at least one electromagnetic shower and one prong. Preliminary results have been obtained and show an excess of 23 ±8.7±14.6 events interpreted as charged current antineutrino electron interactions. In terms of a limit we obtain for the probability P(antineutrino muon → antineutrino electron): P<4.4% (95% C.L.)

  12. Neutrino oscillation study in the muon neutrino → electron neutrino channel at the Brookhaven accelerator

    International Nuclear Information System (INIS)

    The E816 experiment described in this thesis is devoted to a neutrino oscillation search at the Brookhaven AGS. The method used here is to look with a fine grained calorimeter for the appearence of electron neutrino in a muon neutrino beam. After recalling the theoretical treatment of the neutrino mass problem, the experimental phenomenology of massive neutrinos and more specifically neutrino oscillations is reviewed. The experiment itself is then extensively described, both on the technical side (detector, beam, simulation) and on the analysis side. In particular the statistical separation of the electromagnetic showers from electrons - our signal - and from photons - our background - treated in detail. The present analysis is based on 2/3 of the final statistics and it leads to the - preliminary - observation of an electron excess in the neutrino interactions yielding 19 ± 15.6 (stat) ± 7 (syst)

  13. Highway accident involving radiopharmaceuticals near Brookhaven, Mississippi on December 3, 1983

    Energy Technology Data Exchange (ETDEWEB)

    Mohr, P.B.; Mount, M.E.; Schwartz, M.W.

    1985-04-01

    A rear-end collision occurred between a passenger automobile and a luggage trailer carrying 84 packages, 76 of which contained radiopharmaceuticals, on US Highway 84 near Brookhaven, Mississippi on the afternoon of December 3, 1983. The purpose of this report is to document the mechanical circumstances of the accident, confirm the nature and quantity of radioactive materials involved, and assess the nature of the physical environment to which the packages were exposed and the response of the packages. The report consists of three major sections. The first deals wth the nature and circumstances of the accident and findings of fact. The second gives an accounting and description of the materials involved and the consequences of their exposure. The third gives an assessment and analysis of the mechanisms of damage and the conclusions which may be drawn from the investigation. 4 refs., 24 figs., 4 tabs.

  14. Structural biology facilities at Brookhaven National Laboratory`s high flux beam reactor

    Energy Technology Data Exchange (ETDEWEB)

    Korszun, Z.R.; Saxena, A.M.; Schneider, D.K. [Brookhaven National Laboratory, Upton, NY (United States)

    1994-12-31

    The techniques for determining the structure of biological molecules and larger biological assemblies depend on the extent of order in the particular system. At the High Flux Beam Reactor at the Brookhaven National Laboratory, the Biology Department operates three beam lines dedicated to biological structure studies. These beam lines span the resolution range from approximately 700{Angstrom} to approximately 1.5{Angstrom} and are designed to perform structural studies on a wide range of biological systems. Beam line H3A is dedicated to single crystal diffraction studies of macromolecules, while beam line H3B is designed to study diffraction from partially ordered systems such as biological membranes. Beam line H9B is located on the cold source and is designed for small angle scattering experiments on oligomeric biological systems.

  15. Brookhaven highlights, October 1978-September 1979. [October 1978 to September 1979

    Energy Technology Data Exchange (ETDEWEB)

    1979-01-01

    These highlights present an overview of the major research and development achievements at Brookhaven National Laboratory from October 1978 to September 1979. Specific areas covered include: accelerator and high energy physics programs; high energy physics research; the AGS and improvements to the AGS; neutral beam development; heavy ion fusion; superconducting power cables; ISABELLE storage rings; the BNL Tandem accelerator; heavy ion experiments at the Tandem; the High Flux Beam Reactor; medium energy physics; nuclear theory; atomic and applied physics; solid state physics; neutron scattering studies; x-ray scattering studies; solid state theory; defects and disorder in solids; surface physics; the National Synchrotron Light Source ; Chemistry Department; Biology Department; Medical Department; energy sciences; environmental sciences; energy technology programs; National Center for Analysis of Energy Systems; advanced reactor systems; nuclear safety; National Nuclear Data Center; nuclear materials safeguards; Applied Mathematics Department; and support activities. (GHT)

  16. Brookhaven highlights. [Fiscal year 1992, October 1, 1991--September 30, 1992

    Energy Technology Data Exchange (ETDEWEB)

    Rowe, M.S.; Cohen, A.; Greenberg, D.; Seubert, L. [eds.

    1992-12-31

    This publication provides a broad overview of the research programs and efforts being conducted, built, designed, and planned at Brookhaven National Laboratory. This work covers a broad range of scientific disciplines. Major facilities include the Alternating Gradient Synchrotron (AGS), with its newly completed booster, the National Synchrotron Light Source (NSLS), the High Flux Beam Reactor (HFBR), and the RHIC, which is under construction. Departments within the laboratory include the AGS department, accelerator development, physics, chemistry, biology, NSLS, medical, nuclear energy, and interdepartmental research efforts. Research ranges from the pure sciences, in nuclear physics and high energy physics as one example, to environmental work in applied science to study climatic effects, from efforts in biology which are a component of the human genome project to the study, production, and characterization of new materials. The paper provides an overview of the laboratory operations during 1992, including staffing, research, honors, funding, and general laboratory plans for the future.

  17. Heat leak testing of a superconducting RHIC dipole magnet at Brookhaven National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    DeLalio, J.T.; Brown, D.P.; Sondericker, J.H.

    1993-09-01

    Brookhaven National Laboratory is currently performing heat load tests on a superconducting dipole magnet. The magnet is a prototype of the 360, 8 cm bore, arc dipole magnets that will be used in the Relativistic Heavy Ion Collider (RMC). An accurate measurement of the heat load is needed to eliminate cumulative errors when determining the REUC cryogenic system load requirements. The test setup consists of a dipole positioned between two quadrupoles in a common vacuum tank and heat shield. Piping and instrumentation are arranged to facilitate measurement of the heat load on the primary 4.6 K magnet load and the secondary 55 K heat shield load. Initial results suggest that the primary heat load is well below design allowances. The secondary load was found to be higher than estimated, but remained close to the budgeted amount. Overall, the dipole performed to specifications.

  18. Interleaved Carbon Minibeams: An experimental Method of Radiosurgery Developed at Brookhaven National Laboratory

    International Nuclear Information System (INIS)

    Despite recent major innovations in radiation therapy and radiosurgery, there are limitations in treating certain tumors and neurological targets while assuring acceptable damage to the surrounding tissues. These encompass certain tumors in the brain, spinal cord, spinal column, and head-and-neck. This paper describes an experimental radiosurgery, “Interleaved carbon minibeams”1 being developed at the NASA Space Radiation Laboratory (NSRL), Brookhaven National Laboratory (BNL). The method uses arrays of parallel, thin (∼0.3 mm incident beam thickness) planes of carbon ion beams, called carbon minibeams, that “interleave” to produce a solid radiation field at the target . Therefore, the method delivers a solid field of carbon radiation to the target while exposing the surrounding tissues to single arrays of carbon minibeams, which are well tolerated by tissues

  19. The first terawatt picosecond CO2 laser for advanced accelerator studies at the Brookhaven ATF

    International Nuclear Information System (INIS)

    The first terawatt picosecond C02 laser system is under development at the Brookhaven Accelerator Test Facility. Presently operational 1 Joule 100-ps ATF laser will be upgraded with a 10 atm amplifier capable of delivery ∼ 15 Joules of laser energy in a 3 ps pulse. We describe the design of the x-ray preionized 10 atm amplifier of a 10 liter active volume energized by a 1 MV, 200 kA transverse electric discharge. The amplifier, equipped with internal optics, permits the accommodation of a regenerative stage and a multi-pass booster in a relatively compact single discharge volume. The ATF terawatt C02 laser shall become operational in 1997 to serve for laser acceleration, x-ray generation and other strong-field physics experiments

  20. Highway accident involving radiopharmaceuticals near Brookhaven, Mississippi on December 3, 1983

    International Nuclear Information System (INIS)

    A rear-end collision occurred between a passenger automobile and a luggage trailer carrying 84 packages, 76 of which contained radiopharmaceuticals, on US Highway 84 near Brookhaven, Mississippi on the afternoon of December 3, 1983. The purpose of this report is to document the mechanical circumstances of the accident, confirm the nature and quantity of radioactive materials involved, and assess the nature of the physical environment to which the packages were exposed and the response of the packages. The report consists of three major sections. The first deals wth the nature and circumstances of the accident and findings of fact. The second gives an accounting and description of the materials involved and the consequences of their exposure. The third gives an assessment and analysis of the mechanisms of damage and the conclusions which may be drawn from the investigation. 4 refs., 24 figs., 4 tabs

  1. Physics design for the Brookhaven Medical Research Reactor epithermal neutron source

    International Nuclear Information System (INIS)

    A collaborative effort by researchers at the Idaho National Engineering Laboratory and the Brookhaven National Laboratory has resulted in the design and implementation of an epithermal-neutron source at the Brookhaven Medical Research Reactor (BMRR). Large aluminum containers, filled with aluminum oxide tiles and aluminum spacers, were tailored to pre-existing compartments on the animal side of the reactor facility. A layer of cadmium was used to minimize the thermal-neutron component. Additional bismuth was added to the pre-existing bismuth shield to minimize the gamma component of the beam. Lead was also added to reduce gamma streaming around the bismuth. The physics design methods are outlined in this paper. Information available to date shows close agreement between calculated and measured beam parameters. The neutron spectrum is predominantly in the intermediate energy range (0.5 eV - 10 keV). The peak flux intensity is 6.4E + 12 n/(m2.s.MW) at the center of the beam on the outer surface of the final gamma shield. The corresponding neutron current is 3.8E + 12 n/(m2.s.MW). Presently, the core operates at a maximum of 3 MW. The fast-neutron KERMA is 3.6E-15 cGy/(n/m2) and the gamma KERMA is 5.0E-16 cGY/(n/m2) for the unperturbed beam. The neutron intensity falls off rapidly with distance from the outer shield and the thermal flux realized in phantom or tissue is strongly dependent on the beam-delimiter and target geometry

  2. Commercial development considerations

    International Nuclear Information System (INIS)

    Historically, electricity from a nuclear plant has been less expensive than that from a fossil-fuel plant. However, there are other, noneconomic factors that tend to discourage building nuclear power plants. Aside from uranium price and market considerations, other factors that influence the commercial development of a uranium property include estimated capital and operating costs, production lead time, and financial considerations. 8 tables

  3. Cystic fibrosis - nutritional considerations

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/002437.htm Cystic fibrosis - nutritional considerations To use the sharing features on this page, please enable JavaScript. Cystic fibrosis (CF) is a life-threatening disease that causes ...

  4. Celiac disease - nutritional considerations

    Science.gov (United States)

    ... page: //medlineplus.gov/ency/article/002443.htm Celiac disease - nutritional considerations To use the sharing features on this page, please enable JavaScript. Celiac disease is an immune disorder passed down through families. ...

  5. Interactive radiopharmaceutical facility between Yale Medical Center and Brookhaven National Laboratory. Progress report, October 1976-June 1979

    International Nuclear Information System (INIS)

    DOE Contract No. EY-76-S-02-4078 was started in October 1976 to set up an investigative radiochemical facility at the Yale Medical Center which would bridge the gap between current investigation with radionuclides at the Yale School of Medicine and the facilities in the Chemistry Department at the Brookhaven National Laboratory. To facilitate these goals, Dr. Mathew L. Thakur was recruited who joined the Yale University faculty in March of 1977. This report briefly summarizes our research accomplishments through the end of June 1979. These can be broadly classified into three categories: (1) research using indium-111 labelled cellular blood components; (2) development of new radiopharmaceuticals; and (3) interaction with Dr. Alfred Wolf and colleagues in the Chemistry Department of Brookhaven National Laboratory

  6. Department of Energy’s ARM Climate Research Facility External Data Center Operations Plan Located At Brookhaven National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Cialella, A. [Brookhaven National Lab. (BNL), Upton, NY (United States); Gregory, L. [Brookhaven National Lab. (BNL), Upton, NY (United States); Lazar, K. [Brookhaven National Lab. (BNL), Upton, NY (United States); Liang, M. [Brookhaven National Lab. (BNL), Upton, NY (United States); Ma, L. [Brookhaven National Lab. (BNL), Upton, NY (United States); Tilp, A. [Brookhaven National Lab. (BNL), Upton, NY (United States); Wagener, R. [Brookhaven National Lab. (BNL), Upton, NY (United States)

    2015-05-01

    The External Data Center (XDC) Operations Plan describes the activities performed to manage the XDC, located at Brookhaven National Laboratory (BNL), for the Department of Energy’s Atmospheric Radiation Measurement (ARM) Climate Research Facility. It includes all ARM infrastructure activities performed by the Data Management and Software Engineering Group (DMSE) at BNL. This plan establishes a baseline of expectation within the ARM Operations Management for the group managing the XDC.

  7. Management Models and Considerations for Virtual Reference

    OpenAIRE

    Murphy, Joe

    2008-01-01

    This column (from the ongoing column “Better Practices From the Field” in Science & Technology Libraries), explores the major management considerations for developing and maintaining virtual reference services. Topics include staffing models, choosing technologies, training staff, and workflows for diffuse reference services including text messaging reference, instant messaging reference, and reference via emerging library 2.0 and 3.0 venues. Lessons learned and suggested best practices are s...

  8. The Shape and Flow of Heavy Ion Collisions (490th Brookhaven Lecture)

    Energy Technology Data Exchange (ETDEWEB)

    Schenke, Bjoern [BNL Physics Department

    2014-12-18

    The sun can’t do it, but colossal machines like the Relativistic Heavy Ion Collider (RHIC) at Brookhaven Lab and Large Hadron Collider (LHC) in Europe sure can. Quarks and gluons make up protons and neutrons found in the nucleus of every atom in the universe. At heavy ion colliders like RHIC and the LHC, scientists can create matter more than 100,000 times hotter than the center of the sun—so hot that protons and neutrons melt into a plasma of quarks and gluons. The particle collisions and emerging quark-gluon plasma hold keys to understanding how these fundamental particles interact with each other, which helps explain how everything is held together—from atomic nuclei to human beings to the biggest stars—how all matter has mass, and what the universe looked like microseconds after the Big Bang. Dr. Schenke discusses theory that details the shape and structure of heavy ion collisions. He will also explain how this theory and data from experiments at RHIC and the LHC are being used to determine properties of the quark-gluon plasma.

  9. A Really Good Hammer: Quantification of Mass Transfer Using Perfluorocarbon Tracers (475th Brookhaven Lecture)

    Energy Technology Data Exchange (ETDEWEB)

    Watson, Tom [BNL Environmental Sciences, Tracer Technology Group

    2012-02-15

    Brookhaven Lab’s perfluorocarbon tracer (PFT) technology can be viewed as a hammer looking for nails. But, according to Tom Watson, leader of the Lab’s Tracer Technology Group in the Environmental Research and Technology Division (ERTD), “It’s a really good hammer!” The colorless, odorless and safe gases have a number of research uses, from modeling how airborne contaminants might move through urban canyons to help first responders plan their response to potential terrorist attacks and accidents to locating leaks in underground gas pipes. Their extremely low background level — detectable at one part per quadrillion — allows their transport to be easily tracked. Lab researchers used PFTs during the 2005 Urban Dispersion Program field studies in New York City, gathering data to help improve models of how a gas or chemical release might move around Manhattan’s tall buildings and canyons. Closer to home, scientists also used PFTs to make ventilation measurements in Bldg. 400 on the Lab site to provide data to test air flow models used in determining the effects of passive and active air exchange on the levels of indoor and outdoor air pollution, and to determine the effects of an accidental or intentional release of hazardous substances in or around buildings.

  10. What Goes Up Must Come Down: The Lifecycle of Convective Clouds (492nd Brookhaven Lecture)

    Energy Technology Data Exchange (ETDEWEB)

    Jensen, Michael [BNL Environmental Sciences

    2014-02-19

    Some clouds look like cotton balls and others like anvils. Some bring rain, some snow and sleet, and others, just shade. But, whether big and billowy or dark and stormy, clouds affect far more than the weather each day. Armed with measurements of clouds’ updrafts and downdrafts—which resemble airflow in a convection oven—and many other atmospheric interactions, scientists from Brookhaven Lab and other institutions around the world are developing models that are crucial for understanding Earth’s climate and forecasting future climate change. During his lecture, Dr. Jensen provides an overview of the importance of clouds in the Earth’s climate system before explaining how convective clouds form, grow, and dissipate. His discussion includes findings from the Midlatitude Continental Convective Clouds Experiment (MC3E), a major collaborative experiment between U.S. Department of Energy (DOE) and NASA scientists to document precipitation, clouds, winds, and moisture in 3-D for a holistic view of convective clouds and their environment.

  11. Self-Assembly of Nanostructured Electronic Devices (454th Brookhaven Lecture)

    Energy Technology Data Exchange (ETDEWEB)

    Black, Charles [Ph.D., Center for Functional Nanomaterials

    2009-12-16

    Given suitable atmospheric conditions, water vapor from the air will crystallize into beautiful structures: snowflakes. Nature provides many other examples of spontaneous organization of materials into regular patterns, which is a process known as self-assembly. Since self-assembly works at all levels, it can be a useful tool for organizing materials on the nanometer scale. In particular, self-assembly provides a precise method for designing materials with improved electronic properties, thereby enabling advances in semiconductor electronics and solar devices. On Wednesday, December 16, at 4 p.m. in Berkner Hall, Charles Black of the Center for Functional Nanomaterials (CFN) will explore this topic during the 454th Brookhaven Lecture, entitled “Self-Assembly of Nanostructured Electronic Devices.” Refreshments will be offered before and after the lecture. To attend this open-to-the-public event, visitors to the Lab ages 16 and older must present photo ID at the Main Gate. During this talk, Dr. Black will discuss examples of how self-assembly is being integrated into semiconductor microelectronics, as advances in the ability to define circuit elements at higher resolution have fueled more than 40 years of performance improvements. Self-assembly also promises advances in the performance of solar devices; thus he will describe his group’s recent results with nanostructured photovoltaic devices.

  12. In-situ containment of buried waste at Brookhaven National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Dwyer, B.P. [Sandia National Labs., Albuquerque, NM (United States); Heiser, J. [Brookhaven National Lab., Upton, NY (United States); Stewart, W.; Phillips, S. [Applied Geotechnical Engineering and Construction, Inc., Richland, WA (United States)

    1997-12-31

    The primary objective of this project was to further develop close-coupled barrier technology for the containment of subsurface waste or contaminant migration. A close-coupled barrier is produced by first installing a conventional cement grout curtain followed by a thin inner lining of a polymer grout. The resultant barrier is a cement polymer composite that has economic benefits derived from the cement and performance benefits from the durable and chemically resistant polymer layer. The technology has matured from a regulatory investigation of issues concerning barriers and barrier materials to a pilot-scale, multiple individual column injections at Sandia National Labs (SNL) to full scale demonstration. The feasibility of this barrier concept was successfully proven in a full scale {open_quotes}cold test{close_quotes} demonstration at Hanford, WA. Consequently, a full scale deployment of the technology was conducted at an actual environmental restoration site at Brookhaven National Lab (BNL), Long Island, NY. This paper discusses the installation and performance of a technology deployment implemented at OU-1 an Environmental Restoration Site located at BNL.

  13. RHIC and quark matter: proposal for a relativistic heavy ion collider at Brookhaven National Laboratory

    International Nuclear Information System (INIS)

    This document describes the Brookhaven National Laboratory Proposal for the construction of a Relativistic Heavy Ion Collider (RHIC). The construction of this facility represents the natural continuation of the laboratory's role as a center for nuclear and high-energy physics research and extends and uses the existing AGS, Tandem Van de Graaff and CBA facilities at BNL in a very cost effective manner. The Administration and Congress have approved a project which will provide a link between the Tandem Van de Graaf and the AGS. Completion of this project in 1986 will provide fixed target capabilities at the AGS for heavy ions of about 14 GeV/amu with masses up to approx. 30 (sulfur). The addition of an AGS booster would extend the mass range to the heaviest ions (A approx. 200, e.g., gold); its construction could start in 1986 and be completed in three years. These two new AGS experimental facilities can be combined with the proposed Relativistic Heavy Ion Collider to extend the energy range to 100 x 100 GeV/amu for the heaviest ions. BNL proposes to start construction of RHIC in FY 86 with completion in FY 90 at a total cost of 134 M$

  14. In-situ containment of buried waste at Brookhaven National Laboratory

    International Nuclear Information System (INIS)

    The primary objective of this project was to further develop close-coupled barrier technology for the containment of subsurface waste or contaminant migration. A close-coupled barrier is produced by first installing a conventional cement grout curtain followed by a thin inner lining of a polymer grout. The resultant barrier is a cement polymer composite that has economic benefits derived from the cement and performance benefits from the durable and chemically resistant polymer layer. The technology has matured from a regulatory investigation of issues concerning barriers and barrier materials to a pilot-scale, multiple individual column injections at Sandia National Labs (SNL) to full scale demonstration. The feasibility of this barrier concept was successfully proven in a full scale 'cold test' demonstration at Hanford, WA. Consequently, a full scale deployment of the technology was conducted at an actual environmental restoration site at Brookhaven National Lab (BNL), Long Island, NY. This paper discusses the installation and performance of a technology deployment implemented at OU-1 an Environmental Restoration Site located at BNL

  15. Application of the Brookhaven energy-economic assessment model in the Portugal-US cooperative assessment

    Energy Technology Data Exchange (ETDEWEB)

    Rogers, S.; Kyle, S.; McGranahan, G.; Mubayi, V.

    1981-06-01

    This report describes the application of the Brookhaven Energy Economic Assessment Model (BEEAM) in the Portugal-US Cooperative Energy Assessment. Two projections of economic growth provided by the Government of Portugal for the period 1977 to 2010, with 1990 and 2000 as intermediate years, were used to drive the model. The main objectives in applying BEEAM were to investigate for each of the two scenarios and projected reference years the following: the detailed structure of energy demand at a sectoral level; the primary energy resources required to meet the final energy demand; the overall balance of trade due to both energy and nonenergy imports; the consistency or lack thereof between the projected sectoral growth rates; and the implication of the growth rates in regard to aggregate levels fixed capital formation. Additionally, the impacts of the accelerated and moderate energy conservation cases developed on energy demand, resource requirements, and the balance of trade were also determined. The structure of BEEAM, which consists of an energy-denominated input-output representation of the economy coupled to an energy supply-demand network and its mode of application in the Portugal assessment are described in detail in Appendix A.

  16. RHIC and quark matter: proposal for a relativistic heavy ion collider at Brookhaven National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    1984-08-01

    This document describes the Brookhaven National Laboratory Proposal for the construction of a Relativistic Heavy Ion Collider (RHIC). The construction of this facility represents the natural continuation of the laboratory's role as a center for nuclear and high-energy physics research and extends and uses the existing AGS, Tandem Van de Graaff and CBA facilities at BNL in a very cost effective manner. The Administration and Congress have approved a project which will provide a link between the Tandem Van de Graaf and the AGS. Completion of this project in 1986 will provide fixed target capabilities at the AGS for heavy ions of about 14 GeV/amu with masses up to approx. 30 (sulfur). The addition of an AGS booster would extend the mass range to the heaviest ions (A approx. 200, e.g., gold); its construction could start in 1986 and be completed in three years. These two new AGS experimental facilities can be combined with the proposed Relativistic Heavy Ion Collider to extend the energy range to 100 x 100 GeV/amu for the heaviest ions. BNL proposes to start construction of RHIC in FY 86 with completion in FY 90 at a total cost of 134 M$.

  17. Neutron spectrum measurements in the aluminum oxide filtered beam facility at the Brookhaven Medical Research Reactor

    International Nuclear Information System (INIS)

    Neutron spectrum measurements were performed on the aluminum oxide filter installed in the Brookhaven Medical Research Reactor (BMRR). For these measurements, activation foils were irradiated at the exit port of the beam facility. A technique based on dominant resonances in selected activation reactions was used to measure the epithermal neutron spectrum. The fast and intermediate-energy ranges of the neutron spectrum were measured by threshold reactions and 10B-shielded 235U fission reactions. Neutron spectral data were derived from the activation data by two approaches: (1) a short analysis which yields neutron flux values at the energies of the dominant or primary resonances in the epithermal activation reactions and integral flux data for neutrons above corresponding threshold or pseudo-threshold energies, and (2) the longer analysis which utilized all the activation data in a full-spectrum, unfolding process using the FERRET spectrum adjustment code. This paper gives a brief description of the measurement techniques, analysis methods, and the results obtained

  18. Design of small-animal thermal neutron irradiation facility at the Brookhaven Medical Research Reactor

    International Nuclear Information System (INIS)

    The broad beam facility (BBF) at the Brookhaven Medical Research Reactor (BMRR) can provide a thermal neutron beam with flux intensity and quality comparable to the beam currently used for research on neutron capture therapy using cell-culture and small-animal irradiations. Monte Carlo computations were made, first, to compare with the dosimetric measurements at the existing BBF and, second, to calculate the neutron and gamma fluxes and doses expected at the proposed BBF. Multiple cell cultures or small animals could be irradiated simultaneously at the so-modified BBF under conditions similar to or better than those individual animals irradiated at the existing thermal neutron irradiation Facility (TNIF) of the BMRR. The flux intensity of the collimated thermal neutron beam at the proposed BBF would be 1.7 x 1010 n/cm2·s at 3-MW reactor power, the same as at the TNIF. However, the proposed collimated beam would have much lower gamma (0.89 x 10-11 cGy·cm2/nth) and fast neutron (0.58 x 10-11 cGy·cm2/nth) contaminations, 64 and 19% of those at the TNIF, respectively. The feasibility of remodeling the facility is discussed

  19. Retrospective review of the clinical BNCT trial at Brookhaven National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Diaz, A.Z.; Chanana, A.D.; Coderre, J.A.; Ma, R. [Brookhaven National Laboratory, Medical Department, Upton, NY (United States)

    2000-10-01

    The primary objective of the phase I/II dose escalation studies was to evaluate the safety of the boronophenylalanine-fructose (BPA-F) mediated boron neutron capture therapy (BNCT) in subjects with glioblastoma multiforme (GBM). A secondary objective was to retrospectively assess the palliation of GBM by BNCT. Fifty-three subjects with GBM were treated under multiple dose escalation protocols at the Brookhaven Medical Research Reactor (BMRR). Twenty-six subjects were treated using one field, 17 subjects were treated using 2 fields and 10 subjects were treated using 3 fields. BPA-F related toxicity was not observed. The maximum radiation dose to a volume of approximately 1 cc of the normal brain varied from 8.9 to 15.9 gray-equivalent (Gy-Eq). The volume-weighted average radiation dose to normal brain varied from 1.9 to 9.5 Gy-Eq. Six RTOG (Radiation Therapy Oncology Group) grade 3 or 4 toxicities were attributed to BNCT. Four of the 53 subjects are still alive with 3 of them free of recurrent disease with over two years follow-up. The median times to progression and median survival time from diagnosis were 28.4 weeks and 12.8 months respectively. (author)

  20. Effect of the solenoid in various conditions of the laser ion source at Brookhaven National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Ikeda, S., E-mail: ikeda.s.ae@m.titech.ac.jp [Interdisciplinary Graduate School of Science and Engineering, Tokyo Institute of Technology, Yokohama, Kanagawa 216-8502 (Japan); Nishina Center for Accelerator-Based Science, RIKEN, Wako, Saitama 351-0108 (Japan); Kumaki, M. [Nishina Center for Accelerator-Based Science, RIKEN, Wako, Saitama 351-0108 (Japan); Kanesue, T.; Okamura, M. [Collider-Accelerator Department, Brookhaven National Laboratory, Upton, New York 11973-5000 (United States)

    2016-02-15

    In the laser ion source (LIS) at the Brookhaven National Laboratory (BNL), a solenoid is used to guide the laser ablation plasma and modulate the extracted beam current. Many types of ion species are guided. In some cases, the plasma plume is injected into the solenoid away from the solenoidal axis. To investigate the effects of the solenoid on the beam extracted from the plasma that has different properties, the beam current was measured in the setup of the LIS at the BNL. The beam current of Li, Al, Si, Fe, and Au increased when the magnetic field was applied. For most of the species the peak current and the total charge within a single beam pulse increased around 10 times with a magnetic field less than 100 G. In addition, for some species the rate of increase of the peak currents became smaller when the magnetic flux densities were larger than certain values depending on the species. In this case, the current waveforms were distorted. At the same magnetic field value, the field was more effective on lighter species than on heavier ones. When plasma was injected offset from the axis of the solenoid, peak current and total charge became half of those without offset. The experimental data are useful for the operation of the LIS at the BNL.

  1. IEEE 1394 CAMERA IMAGING SYSTEM FOR BROOKHAVENS BOOSTER APPLICATION FACILITY BEAM DIAGNOSTICS

    International Nuclear Information System (INIS)

    Brookhaven's Booster Applications Facility (BAF) will deliver resonant extracted heavy ion beams from the AGS Booster to short-exposure fixed-target experiments located at the end of the BAF beam line. The facility is designed to deliver a wide range of heavy ion species over a range of intensities from 103 to over 108 ions/pulse, and over a range of energies from 0.1 to 3.0 GeV/nucleon. With these constraints we have designed instrumentation packages which can deliver the maximum amount of dynamic range at a reasonable cost. Through the use of high quality optics systems and neutral density light filters we will achieve 4 to 5 orders of magnitude in light collection. By using digital IEEE1394 camera systems we are able to eliminate the frame-grabber stage in processing and directly transfer data at maximum rates of 400 Mb/set. In this note we give a detailed description of the system design and discuss the parameters used to develop the system specifications. We will also discuss the IEEE1394 camera software interface and the high-level user interface

  2. Reliable operation of the Brookhaven EBIS for highly charged ion production for RHIC and NSRL

    Science.gov (United States)

    Beebe, E.; Alessi, J.; Binello, S.; Kanesue, T.; McCafferty, D.; Morris, J.; Okamura, M.; Pikin, A.; Ritter, J.; Schoepfer, R.

    2015-01-01

    An Electron Beam Ion Source for the Relativistic Heavy Ion Collider (RHIC EBIS) was commissioned at Brookhaven in September 2010 and since then it routinely supplies ions for RHIC and NASA Space Radiation Laboratory (NSRL) as the main source of highly charged ions from Helium to Uranium. Using three external primary ion sources for 1+ injection into the EBIS and an electrostatic injection beam line, ion species at the EBIS exit can be switched in 0.2 s. A total of 16 different ion species have been produced to date. The length and the capacity of the ion trap have been increased by 20% by extending the trap by two more drift tubes, compared with the original design. The fraction of Au32+ in the EBIS Au spectrum is approximately 12% for 70-80% electron beam neutralization and 8 pulses operation in a 5 Hertz train and 4-5 s super cycle. For single pulse per super cycle operation and 25% electron beam neutralization, the EBIS achieves the theoretical Au32+ fractional output of 18%. Long term stability has been very good with availability of the beam from RHIC EBIS during 2012 and 2014 RHIC runs approximately 99.8%.

  3. Reliable operation of the Brookhaven EBIS for highly charged ion production for RHIC and NSRL

    International Nuclear Information System (INIS)

    An Electron Beam Ion Source for the Relativistic Heavy Ion Collider (RHIC EBIS) was commissioned at Brookhaven in September 2010 and since then it routinely supplies ions for RHIC and NASA Space Radiation Laboratory (NSRL) as the main source of highly charged ions from Helium to Uranium. Using three external primary ion sources for 1+ injection into the EBIS and an electrostatic injection beam line, ion species at the EBIS exit can be switched in 0.2 s. A total of 16 different ion species have been produced to date. The length and the capacity of the ion trap have been increased by 20% by extending the trap by two more drift tubes, compared with the original design. The fraction of Au32+ in the EBIS Au spectrum is approximately 12% for 70-80% electron beam neutralization and 8 pulses operation in a 5 Hertz train and 4-5 s super cycle. For single pulse per super cycle operation and 25% electron beam neutralization, the EBIS achieves the theoretical Au32+ fractional output of 18%. Long term stability has been very good with availability of the beam from RHIC EBIS during 2012 and 2014 RHIC runs approximately 99.8%

  4. When Protein Crystallography Won't Show You the Membranes (446th Brookhaven Lecture)

    International Nuclear Information System (INIS)

    High fever, stomach ache, coughing, sneezing, and fatigue -- these are all painful signs that you may have caught the flu virus. But how does your body actually 'catch' a virus? Somewhere along the way, the virus infected your body by penetrating the membranes, or surfaces, of some of your body's cells. And then it spreads. Cell membranes are permeable surfaces made of proteins and lipids that allow vital materials to enter and exit cells. Many proteins and cell structures are studied at Brookhaven's National Synchrotron Light Source (NSLS) using a procedure called protein crystallography. But they sometimes have unique characteristics that do not allow them to be easily studied using this widely adopted method. These characteristics make it difficult to understand the cell membrane structure and its ability to both welcome and refuse certain materials and viruses, such as the flu, on behalf of the cell's internal components. Yang will explain the protein crystallography procedure, the simple structure of the cell membrane, and the unusual characteristics of its proteins and lipids. He will also discuss a new, unique method being developed at the NSLS to study proteins and lipids within their native environment as they form the essential permeable surface of a cell membrane.

  5. Status of high current R and D Energy Recovery LINAC at Brookhaven National Laboratory

    International Nuclear Information System (INIS)

    An ampere class 20 MeV superconducting Energy Recovery Linac (ERL) is under construction at Brookhaven National Laboratory (BNL) for testing of concepts relevant for high-energy coherent electron cooling and electron-ion colliders. One of the goals is to demonstrate an electron beam with high charge per bunch (∼ 5 nC) and low normalized emittance (∼ 5 mm-mrad) at an energy of 20 MeV. Flexible lattice of ERL loop provides a test-bed for investigating issues of transverse and longitudinal instabilities, and diagnostics for intense CW e-beam. The superconducting 703 MHz RF photoinjector is considered as an electron source for such a facility. We will start with a straight pass (gun - 5 cell cavity - beam stop) test for the SRF Gun performance studies. Later, we will install and test a novel injection line concept for emittance preservation in a lower energy merger. In this paper we present the status and our plans for construction and commissioning of this facility.

  6. Retrospective review of the clinical BNCT trial at Brookhaven National Laboratory

    International Nuclear Information System (INIS)

    The primary objective of the phase I/II dose escalation studies was to evaluate the safety of the boronophenylalanine-fructose (BPA-F) mediated boron neutron capture therapy (BNCT) in subjects with glioblastoma multiforme (GBM). A secondary objective was to retrospectively assess the palliation of GBM by BNCT. Fifty-three subjects with GBM were treated under multiple dose escalation protocols at the Brookhaven Medical Research Reactor (BMRR). Twenty-six subjects were treated using one field, 17 subjects were treated using 2 fields and 10 subjects were treated using 3 fields. BPA-F related toxicity was not observed. The maximum radiation dose to a volume of approximately 1 cc of the normal brain varied from 8.9 to 15.9 gray-equivalent (Gy-Eq). The volume-weighted average radiation dose to normal brain varied from 1.9 to 9.5 Gy-Eq. Six RTOG (Radiation Therapy Oncology Group) grade 3 or 4 toxicities were attributed to BNCT. Four of the 53 subjects are still alive with 3 of them free of recurrent disease with over two years follow-up. The median times to progression and median survival time from diagnosis were 28.4 weeks and 12.8 months respectively. (author)

  7. Effect of the solenoid in various conditions of the laser ion source at Brookhaven National Laboratory

    International Nuclear Information System (INIS)

    In the laser ion source (LIS) at the Brookhaven National Laboratory (BNL), a solenoid is used to guide the laser ablation plasma and modulate the extracted beam current. Many types of ion species are guided. In some cases, the plasma plume is injected into the solenoid away from the solenoidal axis. To investigate the effects of the solenoid on the beam extracted from the plasma that has different properties, the beam current was measured in the setup of the LIS at the BNL. The beam current of Li, Al, Si, Fe, and Au increased when the magnetic field was applied. For most of the species the peak current and the total charge within a single beam pulse increased around 10 times with a magnetic field less than 100 G. In addition, for some species the rate of increase of the peak currents became smaller when the magnetic flux densities were larger than certain values depending on the species. In this case, the current waveforms were distorted. At the same magnetic field value, the field was more effective on lighter species than on heavier ones. When plasma was injected offset from the axis of the solenoid, peak current and total charge became half of those without offset. The experimental data are useful for the operation of the LIS at the BNL

  8. Effect of the solenoid in various conditions of the laser ion source at Brookhaven National Laboratory

    Science.gov (United States)

    Ikeda, S.; Kumaki, M.; Kanesue, T.; Okamura, M.

    2016-02-01

    In the laser ion source (LIS) at the Brookhaven National Laboratory (BNL), a solenoid is used to guide the laser ablation plasma and modulate the extracted beam current. Many types of ion species are guided. In some cases, the plasma plume is injected into the solenoid away from the solenoidal axis. To investigate the effects of the solenoid on the beam extracted from the plasma that has different properties, the beam current was measured in the setup of the LIS at the BNL. The beam current of Li, Al, Si, Fe, and Au increased when the magnetic field was applied. For most of the species the peak current and the total charge within a single beam pulse increased around 10 times with a magnetic field less than 100 G. In addition, for some species the rate of increase of the peak currents became smaller when the magnetic flux densities were larger than certain values depending on the species. In this case, the current waveforms were distorted. At the same magnetic field value, the field was more effective on lighter species than on heavier ones. When plasma was injected offset from the axis of the solenoid, peak current and total charge became half of those without offset. The experimental data are useful for the operation of the LIS at the BNL.

  9. Genetic markers as a predictive tool based on statistics in medical practice: ethical considerations through the analysis of the use of HLA-B27 in rheumatology in France

    Directory of Open Access Journals (Sweden)

    Hélène eColineaux

    2015-10-01

    Full Text Available INTRODUCTION. The use of genetic predictive markers in medical practice does not necessarily bear the same kind of medical and ethical consequences than that of genes directly involved in monogenic diseases. However, the French bioethics law framed in the same way the production and use of any genetic information. It seems therefore necessary to explore the practical and ethical context of the actual use of predictive markers in order to highlight their specific stakes. In this study, we document the uses of HLA-B*27, which are an interesting example of the multiple features of genetic predictive marker in general medical practice.MATERIAL & METHODS. The aims of this monocentric and qualitative study were to identify concrete and ethical issues of using the HLA-B*27 marker and the interests and limits of the legal framework as perceived by prescribers. In this regard, a thematic and descriptive analysis of five rheumatologists’ semi-structured and face-to-face interviews was performed.RESULTS. According to most of the interviewees, HLA-B*27 is an overframed test because they considered that this test is not really genetic or at least does not have the same nature as classical genetic tests; HLA-B*27 is not concerned by the ethical challenges of genetic test; the major ethics stake of this marker is not linked to its genetic nature but rather to the complexity of the probabilistic information. This study allows also showing that HLA-B*27, validated for a certain usage, may be used in different ways in practice.DISCUSSION. This marker and its clinical uses underline the challenges of translating both statistical concepts and unifying legal framework in clinical practice. This study allows identifying some new aspects and stakes of genetics in medicine and shows the need of additional studies about the use of predictive genetic markers, in order to provide a better basis for decisions and legal framework regarding these practices.

  10. Regulatory good practices relating to monitoring and assessment of ageing nuclear power plants. A compilation of the 1991/92 Peer Group discussion considerations as they relate to operational plants. Working material

    International Nuclear Information System (INIS)

    In 1974 the IAEA established a Nuclear Safety Standards (NUSS) programme within which 5 Codes and 55 Safety Guides have been produced in the areas of Governmental Organization, Siting, Design, Operation and Quality Assurance. The NUSS Codes and Guides are a collection of basic and derived requirements for the safety of nuclear power plants with thermal neutron reactors. They have been developed in such a manner as to ensure the broadest international consensus. This broad consensus is one of the reasons for the relatively general wording of the main principles and sometimes causes problems when these principles are applied in the design of nuclear power plants. The requirements, particularly those of the Codes, often need interpretation in specific cases. In many areas national regulations and technical standards are available, but often these leave some questions unanswered and their practical application on a case-by-case basis is necessary. To assist in the application and interpretation of the NUSS Safety Standards and Safety Guides, the preparation of a number of Safety Practices publications has been commenced. Ibis publication is intended to assist regulators and also operating organizations. It is a compilation of the reports of the 1991/92 Peer Group discussions which considered regulatory good practices relating to monitoring and assessment of the ageing of nuclear power plants. Therefore names of participated countries in this documents are those at time of 1991/92 Peer Group discussions. It identifies those common regulatory features which require continuous reinforcement and examples of good regulatory practices that were recommended by senior regulators in the Peer Group discussions. The purpose of this publication is to provide a compilation of the 1991/92 Peer Group discussions relating to operational plant. This document the covers practices in the 20 countries participating in this round of Peer Group discussions. The document is a synopsis of

  11. 应用型本科环境专业实践教学的思考和探讨%Consideration and Discussion on the Practice Teaching of the Environment Professional in the Application Type Undergraduate

    Institute of Scientific and Technical Information of China (English)

    彭明江

    2014-01-01

    在国家倡导新型职教体系的背景下,有必要思考和探索应用型本科环境专业如何加强实践教学环节,以提高其质量和水平,将培养出高素质的技能型人作为其根本目标,本文介绍环境专业实践教学的内容、形式,对实践教学中存在的问题进行了思考,探讨了加强实践教学环节的措施。%It is necessary to think how to strengthen the practice teaching of the environment professional in the appli-cation type undergraduate to provide its quality and level under the background of that the new vocational education system has been initiated. Training the applied talents with higher quality and technical ability is fundamental objective in the application type undergraduate. This paper introduces the content and form of the practice teaching in the envi-ronment professional, and thinks about the problem of practice teaching, and finally puts forward the measures to strengthen the practice teaching.

  12. Ethical considerations in human experimentation.

    Science.gov (United States)

    Bernstein, J E

    1975-01-01

    An accepted practice in medical research has been the subordination of individual rights to the benefit of mankind. The Nazi experiments, and other recent abuses, have focused increased attention on the dignity and rights of human research subjects and have led to new regulations to control human experimentation. Central to establishing what constitutes permissible human experimentation are the issues of risk-benefit ratio and informed consent. Evaluating the risk-benefit ratio requires consideration of the nature of the experiment, the likelihood of its success, and the type of subjects to be utilized. Participation in a study requires voluntary "educated" informed consent. Certain categories of subjects, such as children and the mentally handicapped, require special protection in this regard. Finally, formal education in medical ethics and prohibiting publication of unethical studies are likely to prove more effective in curbing unethical experimentation than increasing government regulation. PMID:1150912

  13. Burn-Up Calculations for the Brookhaven Graphite Research Reactor Fuel Elements

    International Nuclear Information System (INIS)

    Fuel bum-up calculations for the Brookhaven Graphite Research Reactor involve a distribution of the thermal megawatt days of operations to the fuel elements in proportion to the average thermal neutron flux at their location in the reactor. The megawatt days so assigned can be converted to equivalent uranium-235 consumption when needed. The original fuel loading for the BGRR was neutral uranium and a single calculation was performed on each fuel element upon discharge from the reactor. A subsequent change to a fully enriched uranium-235 fuel element, however, introduced complications. The average loading of enriched uranium involves about 4800 individual elements, each occupying four different reactor positions during its term in the reactor. The total term for a central channel element is about one year as against six to eight years for an element in a peripheral channel. With the large number of individual fuel elements involved and the approximately monthly small changes needed for operation, it was necessary to resort to a computer programme to follow the burn-up of all the elements on the reactor continuously. Both this and other functions of the computer programme are discussed in the paper. To date, uranium has been recovered from two batches of spent fuel. On the first, involving 3674 elements discharged from the reactor over a period of 4.9 years, the recovery figures were 5.5% higher than the calculated total of 32.3 kg uranium-235. On the second batch, involving 1296 elements discharged from the reactor over a period of one year, the recovery figures were 2.3% higher than the calculated figures of 10.8 kg uranium-235. This relatively close agreement seems to indicate that the assumptions made to simplify the programme are acceptable and that the results of the programme are satisfactory for our particular accounting and operating requirements. (author)

  14. Radar Wind Profiler for Cloud Forecasting at Brookhaven National Laboratory (BNL) Field Campaign Report

    Energy Technology Data Exchange (ETDEWEB)

    Jensen, Michael P [Brookhaven National Lab. (BNL), Upton, NY (United States); Giangrande, Scott E [Brookhaven National Lab. (BNL), Upton, NY (United States); Bartholomew, Mary Jane [Brookhaven National Lab. (BNL), Upton, NY (United States)

    2016-04-01

    The Radar Wind Profiler for Cloud Forecasting at Brookhaven National Laboratory (BNL) [http://www.arm.gov/campaigns/osc2013rwpcf] campaign was scheduled to take place from 15 July 2013 through 15 July 2015 (or until shipped for the next U.S. Department of Energy Atmospheric Radiation Measurement [ARM] Climate Research Facility first Mobile Facility [AMF1] deployment). The campaign involved the deployment of the AMF1 Scintec 915 MHz Radar Wind Profiler (RWP) at BNL, in conjunction with several other ARM, BNL and National Weather Service (NWS) instruments. The two main scientific foci of the campaign were: 1) To provide profiles of the horizontal wind to be used to test and validate short-term cloud advection forecasts for solar-energy applications and 2) to provide vertical profiling capabilities for the study of dynamics (i.e., vertical velocity) and hydrometeors in winter storms. This campaign was a serendipitous opportunity that arose following the deployment of the RWP at the Two-Column Aerosol Project (TCAP) campaign in Cape Cod, Massachusetts and restriction from participation in the Green Ocean Amazon 2014/15 (GoAmazon 2014/15) campaign due to radio-frequency allocation restriction for international deployments. The RWP arrived at BNL in the fall of 2013, but deployment was delayed until fall of 2014 as work/safety planning and site preparation were completed. The RWP further encountered multiple electrical failures, which eventually required several shipments of instrument power supplies and the final amplifier to the vendor to complete repairs. Data collection began in late January 2015. The operational modes of the RWP were changed such that in addition to collecting traditional profiles of the horizontal wind, a vertically pointing mode was also included for the purpose of precipitation sensing and estimation of vertical velocities. The RWP operated well until the end of the campaign in July 2015 and collected observations for more than 20 precipitation

  15. Epithermal beam development at the BMRR [Brookhaven Medical Research Reactor]: Dosimetric evaluation

    International Nuclear Information System (INIS)

    The utilization of an epithermal neutron beam for neutron capture therapy (NCT) is desirable because of the increased tissue penetration relative to a thermal neutron beam. Over the past few years, modifications have been and continue to be made at the Brookhaven Medical Research Reactor (BMRR) by changing its filter components to produce an optimal epithermal beam. An optimal epithermal beam should contain a low fast neutron contamination and no thermal neutrons in the incident beam. Recently a new moderator for the epithermal beam has been installed at the epithermal port of the BMRR and has accomplished this task. This new moderator is a combination of alumina (Al2O3) bricks and aluminum (Al) plates. A 0.51 mm thick cadmium (Cd) sheet has reduced the thermal neutron intensity drastically. Furthermore, an 11.5 cm thick bismuth (Bi) plate installed at the port surface has reduced the gamma dose component to negligible levels. Foil activation techniques have been employed by using bare gold and cadmium-covered gold foil to determine thermal as well as epithermal neutron fluence. Fast neutron fluence has been determined by indium foil counting. Fast neutron and gamma dose in soft tissue, free in air, is being determined by the paired ionization chamber technique, using tissue equivalent (TE) and graphite chambers. Thermoluminescent dosimeters (TLD-700) have also been used to determine the gamma dose independently. This paper describes the methods involved in the measurements of the above mentioned parameters. Formulations have been developed and the various corrections involved have been detailed. 12 refs

  16. Brookhaven National Laboratory source water assessment for drinking water supply wells

    International Nuclear Information System (INIS)

    The BNL water supply system meets all water quality standards and has sufficient pumping and storage capacity to meet current and anticipated future operational demands. Because BNL's water supply is drawn from the shallow Upper Glacial aquifer, BNL's source water is susceptible to contamination. The quality of the water supply is being protected through (1) a comprehensive program of engineered and operational controls of existing aquifer contamination and potential sources of new contamination, (2) groundwater monitoring, and (3) potable water treatment. The BNL Source Water Assessment found that the source water for BNL's Western Well Field (comprised of Supply Wells 4, 6, and 7) has relatively few threats of contamination and identified potential sources are already being carefully managed. The source water for BNL's Eastern Well Field (comprised of Supply Wells 10, 11, and 12) has a moderate number of threats to water quality, primarily from several existing volatile organic compound and tritium plumes. The g-2 Tritium Plume and portions of the Operable Unit III VOC plume fall within the delineated source water area for the Eastern Well Field. In addition, portions of the much slower migrating strontium-90 plumes associated with the Brookhaven Graphite Research Reactor, Waste Concentration Facility and Building 650 lie within the Eastern source water area. However, the rate of travel in the aquifer for strontium-90 is about one-twentieth of that for tritium and volatile organic compounds. The Laboratory has been carefully monitoring plume migration, and has made adjustments to water supply operations. Although a number of BNL's water supply wells were impacted by VOC contamination in the late 1980s, recent routine analysis of water samples from BNL's supply wells indicate that no drinking water standards have been reached or exceeded. The high quality of the water supply strongly indicates that the operational and engineered controls implemented over the past

  17. Deployment of Smart 3D Subsurface Contaminant Characterization at the Brookhaven Graphite Research Reactor

    International Nuclear Information System (INIS)

    The Brookhaven Graphite Research Reactor (BGRR) Historical Site Assessment (BNL 1999) identified contamination inside the Below Grade Ducts (BGD) resulting from the deposition of fission and activation products from the pile on the inner carbon steel liner during reactor operations. Due to partial flooding of the BGD since shutdown, some of this contamination may have leaked out of the ducts into the surrounding soils. The baseline remediation plan for cleanup of contaminated soils beneath the BGD involves complete removal of the ducts, followed by surveying the underlying and surrounding soils, then removing soil that has been contaminated above cleanup goals. Alternatively, if soil contamination around and beneath the BGD is either non-existent/minimal (below cleanup goals) or is very localized and can be ''surgically removed'' at a reasonable cost, the BGD can be decontaminated and left in place. The focus of this Department of Energy Accelerated Site Technology Deployment (DOE ASTD) project was to determine the extent (location, type, and level) of soil contamination surrounding the BGD and to present this data to the stakeholders as part of the Engineering Evaluation/Cost Analysis (EE/CA) process. A suite of innovative characterization tools was used to complete the characterization of the soil surrounding the BGD in a cost-effective and timely fashion and in a manner acceptable to the stakeholders. The tools consisted of a tracer gas leak detection system that was used to define the gaseous leak paths out of the BGD and guide soil characterization studies, a small-footprint Geoprobe to reach areas surrounding the BGD that were difficult to access, two novel, field-deployed, radiological analysis systems (ISOCS and BetaScint) and a three-dimensional (3D) visualization system to facilitate data analysis/interpretation. All of the technologies performed as well or better than expected and the characterization could not have been completed in the same time or at

  18. Future management of hazardous wastes generated at Brookhaven National Laboratory, Upton, New York. Environmental assessment

    International Nuclear Information System (INIS)

    This document assesses the potential environmental impacts of a variety of alternatives which could provide a Resource Conservation and Recovery Act (RCRA) permitted waste packaging and storage facility that would handle all hazardous, radioactive, and mixed wastes generated at Brookhaven National Laboratory (BNL) and would operate in full compliance with all federal, state, and local laws and regulations. Location of the existing Hazardous Waste Management Facility (HWMF) with respect to ground water and the site boundary, technical and capacity limitations, inadequate utilities, and required remediation of the area make the existing facility environmentally unacceptable for long term continued use. This Environmental Assessment (EA) describes the need for action by the Department of Energy (DOE). It evaluates the alternatives for fulfilling that need, including the alternative preferred by DOE, a no-action alternative, and other reasonable alternatives. The EA provides a general description of BNL and the existing environment at the current HWMF and alternative locations considered for a new Waste Management Facility (WMF). Finally, the EA describes the potential environmental impacts of the alternatives considered. The preferred alternative, also identified as Alternative D, would be to construct and operate a new WMF on land formerly occupied by barracks during Camp Upton operations, in an area north of Building 830 and the High Flux Beam Reactor/Alternating Gradient Synchrotron (AGS) recharge basins, east of North Railroad Street, and south of East Fifth Avenue. The purpose of this new facility would be to move all storage and transfer activities inside buildings and on paved and curbed areas, consolidate facilities to improve operations management, and provide improved protection of the environment

  19. 915-MHz Wind Profiler for Cloud Forecasting at Brookhaven National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Jensen, M. [Brookhaven National Lab. (BNL), Upton, NY (United States); Bartholomew, M. J. [Brookhaven National Lab. (BNL), Upton, NY (United States); Giangrande, S. [Brookhaven National Lab. (BNL), Upton, NY (United States)

    2016-03-01

    When considering the amount of shortwave radiation incident on a photovoltaic solar array and, therefore, the amount and stability of the energy output from the system, clouds represent the greatest source of short-term (i.e., scale of minutes to hours) variability through scattering and reflection of incoming solar radiation. Providing estimates of this short-term variability is important for determining and regulating the output from large solar arrays as they connect with the larger power infrastructure. In support of the installation of a 37-MW solar array on the grounds of Brookhaven National Laboratory (BNL), a study of the impacts of clouds on the output of the solar array has been undertaken. The study emphasis is on predicting the change in surface solar radiation resulting from the observed/forecast cloud field on a 5-minute time scale. At these time scales, advection of cloud elements over the solar array is of particular importance. As part of the BNL Aerosol Life Cycle Intensive Operational Period (IOP), a 915-MHz Radar Wind Profiler (RWP) was deployed to determine the profile of low-level horizontal winds and the depth of the planetary boundary layer. The initial deployment mission of the 915-MHz RWP for cloud forecasting has been expanded the deployment to provide horizontal wind measurements for estimating and constraining cloud advection speeds. A secondary focus is on the observation of dynamics and microphysics of precipitation during cold season/winter storms on Long Island. In total, the profiler was deployed at BNL for 1 year from May 2011 through May 2012.

  20. Chernobyl: Geographic considerations

    International Nuclear Information System (INIS)

    This paper discusses the geographic considerations that could effect the long range consequences of the Chernobyl accident. First, the explosion and fire lofted the radionuclides that were released, so the areas that should have been most severely effected were the areas that were downwind of the accident. Curiously, the Soviets have not mentioned the number of casualties from these areas. A second consideration is that Chernobyl is located upstream from the Dnieper River which is the source for six major reservoirs. These reservoirs provide drinking water, industrial and irrigation water, and recreational and commercial fishing for over six million people. The Soviets say that they have taken measures to prevent the radioactive contamination of the Dnieper but they neglected to explain the methods used to accomplish this feat

  1. Percutaneous vertebroplasty: technical considerations

    Institute of Scientific and Technical Information of China (English)

    Gao-jun TENG; Shi-cheng HE

    2005-01-01

    Percutaneous vertebroplasty (PVP) is a relative new interventional technique, which is widely used in treatment of vertebral collapse caused by vertebral neoplasms and osteoporotic compression fractures. The general technical considerations of PVP techniques are discussed based on authors' experience obtained over 400 patients in the past years in this article, including preparation of PMMA, instrument of PVP, guidance and puncture approaches, and technique of the procedure, etc. The conclusion is that PVP is a safe procedure if the physicians handle it properly.

  2. Security consideration for virtualization

    OpenAIRE

    Gebhardt, Carl

    2008-01-01

    Virtualization is not a new technology, but has recently experienced a resurgence of interest among industry and research. New products and technologies are emerging quickly, and are being deployed with little considerations to security concerns. It is vital to understand that virtualization does not improve security by default. Hence, any aspect of virtualization needs to undergo constant security analysis and audit. Virtualization is a changeable and very dynamic field wit...

  3. Fusion facility siting considerations

    International Nuclear Information System (INIS)

    Inherent in the fusion program's transition from hydrogen devices to commercial power machines is a general increase in the size and scope of succeeding projects. This growth will lead to increased emphasis on safety, environmental impact, and the external effects of fusion in general, and of each new device in particular. A critically important consideration in this regard is site selection. The purpose of this paper is to examine major siting issues that may affect the economics, safety, and environmental impact of fusion

  4. Educational Neuroscience: Neuroethical Considerations

    Science.gov (United States)

    Lalancette, Helene; Campbell, Stephen R.

    2012-01-01

    Research design and methods in educational neuroscience involve using neuroscientific tools such as brain image technologies to investigate cognitive functions and inform educational practices. The ethical challenges raised by research in social neuroscience have become the focus of neuroethics, a sub-discipline of bioethics. More specifically…

  5. Cultural Considerations in Translation

    Institute of Scientific and Technical Information of China (English)

    陈嫔荣

    2009-01-01

    Language is the expression of human communication through which knowledge, belief, and behavior can be experi-enced, explained, and shared. It influences the way the speakers perceive the world. But as it has been long taken for granted, translation deals only with language. Cultural perspective, however, has never been brought into discussion. This paper first analyses the definitions of translation and culture, and then discusses why we should take culture into consideration and in the end, two translating strategies:domestication and foreignization are introduced.

  6. Cultural Considerations in Translation

    Institute of Scientific and Technical Information of China (English)

    陈嫔荣

    2009-01-01

    Language is the expression of human communication through which knowledge, belief, and behavior can be experi- enced, explained, and shared. It influences the way the speakers perceive the world. But as it has been long taken for granted, translation deals only with language. Cultural perspective, however, has never been brought into discussion. This paper first analyses the definitions of translation and culture, and then discusses why we should take culture into consideration and in the end, two translating strategies: domestication and foreignization are introduced.

  7. Part 8. Deployment considerations

    International Nuclear Information System (INIS)

    This report addresses considerations of fast breeder reactor development and deployment from a national perspective. Nations vary greatly in their expertise and interest relative to nuclear power, and hence a single set of steps to be taken by a nation in decision-making on breeder development and deployment cannot be presented. The approach taken in this report is to present discussions on key factors influencing the breeder development and deployment decisions, especially in non-breeder nations, by drawing upon historical perspectives of the Light Water Reactor for comparison

  8. Present and future directions of atomic physics research with multiply-charged ions at Brookhaven National Laboratory

    International Nuclear Information System (INIS)

    Atomic physics research with multiply-charged ions is now in progress using ion beams from the Brookhaven Double MP-Tandem van de Graaff facility. In the near future, experiments will start using ions produced by photons from the National Synchrotron Light Source (NSLS). Examples of typical experiments are discussed to illustrate the comprehensive nature of these facilities. Plans for future expansion by addition of a CRYEBIS type ion source coupled to a heavy-ion storage ring for use in crossed-beam experiments at the NSLS are discussed. 18 refs., 8 figs

  9. Risk assessment and optimization (ALARA) analysis for the environmental remediation of Brookhaven National Laboratory's hazardous waste management facility

    International Nuclear Information System (INIS)

    The Department of Energy's (DOE) Office of Environment, Safety, and Health (EH) sought examples of risk-based approaches to environmental restoration to include in their guidance for DOE nuclear facilities. Extensive measurements of radiological contamination in soil and ground water have been made at Brookhaven National Laboratory's Hazardous Waste Management Facility (HWMF) as part of a Comprehensive Environmental Response, Compensation and Liability Act (CERCLA) remediation process. This provided an ideal opportunity for a case study. This report provides a risk assessment and an open-quotes As Low as Reasonably Achievableclose quotes (ALARA) analysis for use at other DOE nuclear facilities as an example of a risk-based decision technique

  10. Proceedings of RIKEN BNL Research Center Workshop: Brookhaven Summer Program on Nucleon Spin Physics

    Energy Technology Data Exchange (ETDEWEB)

    Aschenauer, A.; Qiu, Jianwei; Vogelsang, W.; Yuan, F.

    2011-08-02

    Understanding the structure of the nucleon is of fundamental importance in sub-atomic physics. Already the experimental studies on the electro-magnetic form factors in the 1950s showed that the nucleon has a nontrivial internal structure, and the deep inelastic scattering experiments in the 1970s revealed the partonic substructure of the nucleon. Modern research focuses in particular on the spin and the gluonic structure of the nucleon. Experiments using deep inelastic scattering or polarized p-p collisions are carried out in the US at the CEBAF and RHIC facilities, respectively, and there are other experimental facilities around the world. More than twenty years ago, the European Muon Collaboration published their first experimental results on the proton spin structure as revealed in polarized deep inelastic lepton-nucleon scattering, and concluded that quarks contribute very little to the proton's spin. With additional experimental and theoretical investigations and progress in the following years, it is now established that, contrary to naive quark model expectations, quarks and anti-quarks carry only about 30% of the total spin of the proton. Twenty years later, the discovery from the polarized hadron collider at RHIC was equally surprising. For the phase space probed by existing RHIC experiments, gluons do not seem to contribute any to the proton's spin. To find out what carries the remaining part of proton's spin is a key focus in current hadronic physics and also a major driving force for the new generation of spin experiments at RHIC and Jefferson Lab and at a future Electron Ion Collider. It is therefore very important and timely to organize a series of annual spin physics meetings to summarize the status of proton spin physics, to focus the effort, and to layout the future perspectives. This summer program on 'Nucleon Spin Physics' held at Brookhaven National Laboratory (BNL) on July 14-27, 2010 [http://www.bnl.gov/spnsp/] is the

  11. Radiation sterilization - chemical considerations

    International Nuclear Information System (INIS)

    The effects of ionizing radiation on cartilage and on a protein polysaccharide extract (CMP) from cartilage are evaluated. The results indicate that the hydroxyl radicals (produced when ionizing radiation interacts with water) are the most important species in altering the integrity of the cartilage during sterilization. Further data show how suitably designed chemial agents can protect the tissue from radiation damage. It is now hoped that practical use can be made of these developments during the radiation sterilization of tissues. (author)

  12. Non-proliferation considerations

    International Nuclear Information System (INIS)

    This paper reiterates the Indian viewpoint that consideration of ''proliferation resistance'' is outside the terms of reference of Working Group 4 as agreed at the Washington Conference. The discussions in WG4 should therefore cover only safeguards aspects. The paper goes on to critisize the various assessment factors introduced in INFCE/DEP./WG-4/104 and the various alternative technologies proposed. The Indian view is reinstated that if a country requires reprocessing based on its nuclear energy programmes and priorities, there should be no hindrance. International safeguards should be applied to all nuclear materials in all countries without discrimination or differentiation between civil and military programmes. The paper concludes that non-proliferation is essentially a political matter and has no technical solution

  13. Percutaneous Penetration - Methodological Considerations

    DEFF Research Database (Denmark)

    Holmgaard, Rikke; Benfeldt, Eva; Nielsen, Jesper B

    2014-01-01

    developed to replace methods involving experimental animals. The results obtained from these methods are decided not only by the chemical or product tested, but to a significant degree also by the experimental set-up and decisions made by the investigator during the planning phase. The present Mini......Studies on percutaneous penetration are needed to assess the hazards after unintended occupational skin exposures to industrial products as well as the efficacy after intended consumer exposure to topically applied medicinal or cosmetic products. During recent decades, a number of methods have been......Review discusses some of the existing and well-known experimental in vitro and in vivo methods for studies of percutaneous penetration together with some more recent and promising methods. After this, some considerations and recommendations about advantages and limitations of the different methods and their...

  14. PROJECT-SPECIFIC TYPE A VERIFICATION FOR THE HIGH FLUX BEAM REACTOR UNDERGROUND UTILITIES REMOVAL PHASE 3 TRENCH 5, BROOKHAVEN NATIONAL LABORATORY UPTON, NEW YORK

    International Nuclear Information System (INIS)

    The Oak Ridge Institute for Science and Education (ORISE) has reviewed the project documentation and data for the High Flux Beam Reactor (HFBR) Underground Utilities removal Phase 3; Trench 5 at Brookhaven National Laboratory (BNL) in Upton, New York. The Brookhaven Survey Group (BSG) has completed removal and performed Final Status Survey (FSS) of the concrete duct from Trench 5 from Building 801 to the Stack. Sample results have been submitted as required to demonstrate that the cleanup goal of (le)15 mrem/yr above background to a resident in 50 years has been met. Four rounds of sampling, from pre-excavation to FSS, were performed as specified in the Field Sampling Plan (FSP) (BNL 2010a). It is the policy of the U.S. Department of Energy (DOE) to perform independent verifications of decontamination and decommissioning activities conducted at DOE facilities. ORISE has been designated as the organization responsible for this task for the HFBR Underground Utilities. ORISE, together with DOE, determined that a Type A verification of Trench 5 was appropriate based on recent verification results from Trenches 2, 3, and 4, and the minimal potential for residual radioactivity in the area. The removal of underground utilities is being performed in three stages to decommission the HFBR facility and support structures. Phase 3 of this project included the removal of at least 200 feet of 36-inch to 42-inch pipe from the west side to the south side of Building 801, and the 14-inch diameter Acid Waste Line that spanned from 801 to the Stack within Trench 5. Based on the pre-excavation sample results of the soil overburden the potential for contamination of the soil surrounding the pipe is minimal (BNL 2010a). ORISE reviewed the BNL FSP and identified comments for consideration (ORISE 2010). BNL prepared a revised FSP that resolved each ORISE comment adequately (BNL 2010a). ORISE referred to the revised HFBR Underground Utilities FSP FSS data to conduct the Type A verification

  15. Summary update of the Brookhaven tritium toxicity program with emphasis on recent cytogenetic and lifetime-shortening studies

    International Nuclear Information System (INIS)

    A number of years ago a multiparameter program to evaluate the toxicity of tritiated water (HTO) was undertaken in the Medical Department at Brookhaven National Laboratory. The results of most of these studies have been published and will receive brief attention. Emphasis will be placed on the unpublished studies involving the induction of sister chromatid exchanges (SCE's) in bone marrow of mice, new biochemical information, and preliminary results on lifetime-shortening and carcinogenesis. In brief, male Hale-Stoner Brookhaven (HSB) mice maintained on HTO concentrations ranging from 3.0 to 30.0 μCi/ml exhibited essentially the same number of SCE's per cell throughout their lifetime. Control mice showed a decrease in number of SCE's with age. The lack of a dose-response effect and the constant level of SCE's in HTO mice as compared to controls will be discussed. In the carcinogenesis study C57BL/6J male mice received various x-ray or HTO regimens. Mortality data from these and other studies in which CBA/Ca/BNL mice received single x-ray exposures or equivalent integrated dose exposures by single HTO injections will be discussed. 25 refs., 4 figs

  16. Considerations of the factors affecting the clinical practice of medical students in interventional radiology at present%现阶段介入放射学临床实习影响因素探讨

    Institute of Scientific and Technical Information of China (English)

    魏宁; 徐浩; 祖茂衡; 顾玉明; 张庆桥; 许伟; 崔艳峰; 刘洪涛; 王文亮

    2014-01-01

    As a newly - developed medical subject, interventional radiology has been widely popularized for recent years., Taking the first affiliated hospital of Xuzhou medical college for instance, this paper aims to discuss the following three major factors that influence the clinical practice of medical students in interventional radiology at present: the importance to clinical teaching, the changes of doctor-patient relationship and the professional ethic quality education. The perfection measures and countermeasures are also discussed.%介入放射学是一门新兴学科,近年来在临床上得到了广泛普及。本文以徐州医学院附属医院为例,提出现阶段医学生在介入放射科临床实习过程中应重视三个主要影响因素:临床教学重视力度、医患关系变化和职业道德素质教育,并探讨改进措施和对策。

  17. Some Considerations on the Elements of Practicing the Socialist Democratic Consultation%关于实践社会主义协商民主要素的几点思考

    Institute of Scientific and Technical Information of China (English)

    王德彬

    2015-01-01

    To actively and stably implement the socialist demo-cratic consultation construction is an important means to fully carry forward the unique advantages of China's socialist democ-racy and continuously improve the modernization of country gov-ernance. Meanwhile, the practice of the socialist democratic con-sultation needs several key elements, such as the diversification and equality of the subject, the diversity and openness of the ob-ject, the integrity and legality of the process, as well as the mutual inclusiveness and public rationality of the democratic consulta-tion.%积极稳妥推进社会主义协商民主建设,是充分发扬我国社会主义民主的独特优势,不断提升国家治理现代化水平的一个重要手段。同时,实践社会主义协商民主离不开协商民主主体的多元性和平等性、客体的多样性和公开性、程序的完整性和合法性以及协商民主的相互包容性和公共理性等几个关键要素。

  18. 政府环保网站信息公开的实践与思考%Practice and Consideration on Information Disclosure of the Government Environmental Protection Website

    Institute of Scientific and Technical Information of China (English)

    孔雁波

    2015-01-01

    The government environmental protection website is the first information disclosure platform of the environmental protection department of the government and also is an important channel for community assess to the environmental information.In order to give full play to the function of information disclosure and transfer the governmental voice for the first time to society through the government environmental protection website,the paper discussed four aspects about environmental information disclosure with practical experience:releasing information,organizing environmental information,spreading government environmental information more efficiently,ensuring environmental information disclosure.%政府环保网站是政府环保部门信息公开的第一平台,也是社会获取环境信息的重要渠道。为充分发挥政府环保网站环境信息公开的功能,将政府的声音在第一时间传递给社会,结合实践经验,文章从发布环境信息、整理环境信息、提升环境信息传播能力、保障环境信息公开四个方面给出建议。

  19. Paediatricians, social media and blogs: Ethical considerations

    OpenAIRE

    St-Laurent-Gagnon, Thérèse; Coughlin, Kevin W

    2012-01-01

    The use of blogs, Facebook and similar social networking sites is rapidly expanding and, when compared with e-mail, may be having a significantly different impact on the traditional doctor-patient relationship. Characteristics specific to these online platforms have major implications for professional relationships, including the ‘Facebook effect’ (the relative permanence of postings) and the ‘online disinhibition effect’. The present practice point illustrates relevant ethical considerations...

  20. Methodologic Considerations and Conclusions

    Directory of Open Access Journals (Sweden)

    Federica Chiesa

    2013-11-01

    Full Text Available After the theoric seasons of the second middle of the Twenthieth century especially by the anglo-american Scholars and the beginning of the open area excavations enterprises in Italy thirty years ago, the concept of the therm “method” holds now a multiplicity of aspects one another connected; their theorical and practical applications make valuable the method universality but it depends on the characteristics of the archaeological site too. So Nora with its historical-archaeological stratification is an exemplary specimen from a lot of points of view like a precious source to draw stratigraphical sequences inside  large chronological oasis with very important monumental contexts. The universitary équipes were allowed to adopt a modern methodological practice, founded on technological resources, that leads to a perspective which contains the archaeology of architecture and the archaeology of the smallest clue compared together. The fast and careful editions of the field-works in the “Quaderni Norensi” Collection, enriched by an exhaustive documentary evidence, constitutes an indispensable contribution to the reconstruction of the ancient town and the best trial to test a research model “open-area” between équipes differently formed but in a scientific homogeneous climate.

  1. Modelling Practice

    DEFF Research Database (Denmark)

    Cameron, Ian; Gani, Rafiqul

    2011-01-01

    This chapter deals with the practicalities of building, testing, deploying and maintaining models. It gives specific advice for each phase of the modelling cycle. To do this, a modelling framework is introduced which covers: problem and model definition; model conceptualization; model data...... requirements; model construction; model solution; model verification; model validation and finally model deployment and maintenance. Within the adopted methodology, each step is discussedthrough the consideration of key issues and questions relevant to the modelling activity. Practical advice, based on many...... years of experience is providing in directing the reader in their activities.Traps and pitfalls are discussed and strategies also given to improve model development towards “fit-for-purpose” models. The emphasis in this chapter is the adoption and exercise of a modelling methodology that has proven very...

  2. Experimental Hall design considerations

    International Nuclear Information System (INIS)

    General requirements for experimental halls at the Fermilab Collider are set forth, and specific designs for two halls are presented, one for the Detector Group's large ''W detector'' and the other for several smaller setups and for ep experiments. The physics which cannot be studied with the W detector is surveyed, and it is recommended that the second area incorporate a transposed geometry to allow small angle experiments. The most important recommendations are (1) that the halls have good access and the possibility of changing entire setups during short shutdowns, (2) that both equal energy (anti pp) and unequal energy (pp, ep) experiments be accommodated, (3) that construction take place during the superconducting ring installation, (4) that the halls incorporate assembly areas in which detectors can be built and serviced during machine operation and (5) that detailed design, including radiation safety calculations and muon background measurements, begin immediately. Some basic questions concerning the nature of the experimental halls needed for colliding beam experiments at Fermilab are discussed. General requirements and design considerations are dealt with first, followed by specific proposals for the layout of actual halls

  3. Civic ecology practices: insights from practice theory

    Directory of Open Access Journals (Sweden)

    Marianne E. Krasny

    2015-06-01

    Full Text Available Our aim was to explore the use of practice theory as an approach to studying urban environmental stewardship. Urban environmental stewardship, or civic ecology practice, contributes to ecosystem services and community well-being and has been studied using social-ecological systems resilience, property rights, communities of practice, and governance frameworks. Practice theory, which previously has been applied in studies of consumer behaviors, adds a new perspective to urban stewardship research, focusing on how elements of a practice, such as competencies, meanings, and physical resource, together define the practice. We applied practice theory to eight different civic ecology practices, including oyster gardening in New York City, a civil society group engaged in litter cleanup in Iran, and village grove restoration in South Korea. Our analysis suggests that in applying practice theory to the civic ecology context, consideration should be given to social and communication competencies, how meanings can motivate volunteers and sustain practice, and the nature of the resource that is being stewarded. Future studies may want to focus on how practice elements interact within and vary across practices and may be used to more systematically analyze and share ideas among diverse civic ecology practices.

  4. Consideraciones prácticas acerca de la calidad del semen de conejos aplicado en estudios de toxicología de la fertilidad (Practice considerations about the semen quality of rabbits for applied in fertility toxicology study.

    Directory of Open Access Journals (Sweden)

    Arencibia Arrebola Daniel Francisco

    2009-08-01

    the pharmaceutics products, that its influence in the female and male fertility. The methods of semen quality valuation in artificialinsemination and research were suffering a constant development toestimate with more precision the males fertility. Unfortunately, thelaboratory valuations don't predict with accuracy the fertility and not obtained the repetitive of some analyses to other, because of thesubjectivity of many valuations. The objective of this work is the making of a theoretical-practice guide that allows to carry out studies of the semen in rabbits, (New Zealand White breed, applied to the fertility toxicology thematic. We will treat the topics of the zeal induction in the females, conditions and method for the semen extraction, macroscopic and microscopic semen tests, organs weight valuation and anatomopatologic exam. All the described tests contribute data that will indicate a decrease of the semen quality, but we should carry out valuations that contribute simplicity, speed and they are economically viable; the researcher should be use the best option for his work conditions.

  5. Neonatal euthanasia: moral considerations and criminal liability.

    Science.gov (United States)

    Sklansky, M

    2001-02-01

    Despite tremendous advances in medical care for critically ill newborn infants, caregivers in neonatal intensive care units still struggle with how to approach those patients whose prognoses appear to be the most grim, and whose treatments appear to be the most futile. Although the practice of passive neonatal euthanasia, from a moral perspective, has been widely (albeit quietly) condoned, those clinicians and families involved in such cases may still be found legally guilty of child abuse or even manslaughter. Passive neonatal euthanasia remains both a moral dilemma and a legal ambiguity. Even the definition of passive euthanasia remains unclear. This manuscript reviews the basic moral and legal considerations raised by the current practice of neonatal euthanasia, and examines the formal position statements of the American Medical Association and the American Academy of Pediatrics. The paper concludes by emphasising the need, at least in the United States, to clarify the legal status of this relatively common medical practice. PMID:11233379

  6. Engineering radioecology: Methodological considerations

    International Nuclear Information System (INIS)

    The term ''radioecology'' has been widely recognized in scientific and technical societies. At the same time, this scientific school (radioecology) does not have a precise/generally acknowledged structure, unified methodical basis, fixed subjects of investigation, etc. In other words, radioecology is a vast, important but rather amorphous conglomerate of various ideas, amalgamated mostly by their involvement in biospheric effects of ionizing radiation and some conceptual stereotypes. This paradox was acceptable up to a certain time. However, with the termination of the Cold War and because of remarkable political changes in the world, it has become possible to convert the problem of environmental restoration from the scientific sphere in particularly practical terms. Already the first steps clearly showed an imperfection of existing technologies, managerial and regulatory schemes; lack of qualified specialists, relevant methods and techniques; uncertainties in methodology of decision-making, etc. Thus, building up (or maybe, structuring) of special scientific and technological basis, which the authors call ''engineering radioecology'', seems to be an important task. In this paper they endeavored to substantiate the last thesis and to suggest some preliminary ideas concerning the subject matter of engineering radioecology

  7. Brookhaven Regional Energy Facility Siting Model (REFS): model development and application

    Energy Technology Data Exchange (ETDEWEB)

    Meier, P.; Hobbs, B.; Ketcham, G.; McCoy, M.; Stern, R.

    1979-06-01

    A siting methodology developed specifically to bridge the gap between regional-energy-system scenarios and environmental transport models is documented. Development of the model is described in Chapter 1. Chapter 2 described the basic structure of such a model. Additional chapters on model development cover: generation, transmission, demand disaggregation, the interface to other models, computational aspects, the coal sector, water resource considerations, and air quality considerations. These subjects comprise Part I. Part II, Model Applications, covers: analysis of water resource constraints, water resource issues in the New York Power Pool, water resource issues in the New England Power Pool, water resource issues in the Pennsylvania-Jersey-Maryland Power Pool, and a summary of water resource constraint analysis. (MCW)

  8. Construction and operation of a 10 MeV electron accelerator and associated experimental facilities at Brookhaven National Laboratory, Upton, New York. Environmental assessment

    International Nuclear Information System (INIS)

    The purpose of this environmental impact statement is to determine whether there would be significant environmental impacts associated with the construction of an experimental facility at Brookhaven National Laboratory for radiation chemistry research and operation of the 10-MeV electron accelerator proposed for it. The document describes the need for action, alternative actions, the affected environment, and potential environmental impacts

  9. g-2 of the Muon : After 10 years still a puzzle for the now consistent theory - The Brookhaven Experiment moves to Fermilab

    NARCIS (Netherlands)

    Jungmann, Klaus P.

    2012-01-01

    The experimental value a _μ^\\rmexp for the muon magnetic anomaly measured at the Brookhaven National Laboratory (BNL), Upton, USA, and the latest theoretical value a _μ^\\rmtheo based on a number of calculations and auxiliary experiments differ today by 3.3 standard deviations. Discrepancies between

  10. REVISED INDEPENDENT VERIFICATION SURVEY OF THE A AND B RADIOACTIVE WASTE TRANSFER LINES TRENCH BROOKHAVEN NATIONAL LABORATORY UPTON, NEW YORK

    International Nuclear Information System (INIS)

    The objective of the verification survey was to obtain evidence by means of measurements and sampling to confirm that the final radiological conditions were less than the established release criteria. This objective was achieved via multiple verification components including document reviews to determine the accuracy and adequacy of FSS documentation. During the period between September 28 and 29, 2009 and December 9 and 10, 2009 an independent verification team with the Oak Ridge Institute for Science and Education conducted measurements and sampling of the A and B Radioactive Waste Transfer Line Trench at the Brookhaven National Laboratory site. Gamma walkover scans did not identify radiation levels that warranted additional investigation. ORISE collected ten judgmental soil samples. All individual samples and the corresponding mean concentration were determined to be below the established cleanup goals. Therefore, it is the opinion of ORISE that the remedial actions implemented by BNL sufficiently meet the established clean-up goals.

  11. A service-based SLA (Service Level Agreement) for the RACF (RHIC and ATLAS computing facility) at brookhaven national lab

    International Nuclear Information System (INIS)

    The RACF provides computing support to a broad spectrum of scientific programs at Brookhaven. The continuing growth of the facility, the diverse needs of the scientific programs and the increasingly prominent role of distributed computing requires the RACF to change from a system to a service-based SLA with our user communities. A service-based SLA allows the RACF to coordinate more efficiently the operation, maintenance and development of the facility by mapping out a matrix of system and service dependencies and by creating a new, configurable alarm management layer that automates service alerts and notification of operations staff. This paper describes the adjustments made by the RACF to transition to a service-based SLA, including the integration of its monitoring software, alarm notification mechanism and service ticket system at the facility to make the new SLA a reality.

  12. Risk assessment and optimization (ALARA) analysis for the environmental remediation of Brookhaven National Laboratory`s hazardous waste management facility

    Energy Technology Data Exchange (ETDEWEB)

    Dionne, B.J.; Morris, S.C. III; Baum, J.W. [and others

    1998-01-01

    The Department of Energy`s (DOE) Office of Environment, Safety, and Health (EH) sought examples of risk-based approaches to environmental restoration to include in their guidance for DOE nuclear facilities. Extensive measurements of radiological contamination in soil and ground water have been made at Brookhaven National Laboratory`s Hazardous Waste Management Facility (HWMF) as part of a Comprehensive Environmental Response, Compensation and Liability Act (CERCLA) remediation process. This provided an ideal opportunity for a case study. This report provides a risk assessment and an {open_quotes}As Low as Reasonably Achievable{close_quotes} (ALARA) analysis for use at other DOE nuclear facilities as an example of a risk-based decision technique. This document contains the Appendices for the report.

  13. Risk assessment and optimization (ALARA) analysis for the environmental remediation of Brookhaven National Laboratory`s hazardous waste management facility

    Energy Technology Data Exchange (ETDEWEB)

    Dionne, B.J.; Morris, S. III; Baum, J.W. [and others

    1998-03-01

    The Department of Energy`s (DOE) Office of Environment, Safety, and Health (EH) sought examples of risk-based approaches to environmental restoration to include in their guidance for DOE nuclear facilities. Extensive measurements of radiological contamination in soil and ground water have been made at Brookhaven National Laboratory`s Hazardous Waste Management Facility (HWMF) as part of a Comprehensive Environmental Response, Compensation and Liability Act (CERCLA) remediation process. This provided an ideal opportunity for a case study. This report provides a risk assessment and an {open_quotes}As Low as Reasonably Achievable{close_quotes} (ALARA) analysis for use at other DOE nuclear facilities as an example of a risk-based decision technique.

  14. Technical Safety Requirement Violation at the High Flux Beam Reactor Decommissioning Project, Brookhaven, United States of America

    International Nuclear Information System (INIS)

    At Brookhaven National Laboratory (BNL) on 6 July 2009, a technical safety requirement (TSR) violation was declared at the high flux beam reactor (HFBR) project, which was a limited scope decontamination and decommissioning project associated with the permanently shutdown reactor. The violation extended from performing decommissioning activities within the facility under the incorrect mode. The draining of the spent fuel pool was performed in the warm standby mode when it should have been in the operation mode. The TSR was developed contrary to the United States Department of Energy (DOE) TSR guidance, which recommends that facility operations should only be carried out in the operation mode. The facility TSR allowed operations to be carried out in both modes. The HFBR operation mode focused on the removal of a small number of highly irradiated components with associated limited conditions of operation (LCO), while the warm standby mode focused on all other tasks in the facility and did not require entry into the LCO

  15. Risk assessment and optimization (ALARA) analysis for the environmental remediation of Brookhaven National Laboratory's hazardous waste management facility

    International Nuclear Information System (INIS)

    The Department of Energy's (DOE) Office of Environment, Safety, and Health (EH) sought examples of risk-based approaches to environmental restoration to include in their guidance for DOE nuclear facilities. Extensive measurements of radiological contamination in soil and ground water have been made at Brookhaven National Laboratory's Hazardous Waste Management Facility (HWMF) as part of a Comprehensive Environmental Response, Compensation and Liability Act (CERCLA) remediation process. This provided an ideal opportunity for a case study. This report provides a risk assessment and an open-quotes As Low as Reasonably Achievableclose quotes (ALARA) analysis for use at other DOE nuclear facilities as an example of a risk-based decision technique. This document contains the Appendices for the report

  16. OPTIMIZATION OF THE EPITHERMAL NEUTRON BEAM FOR BORON NEUTRON CAPTURE THERAPY AT THE BROOKHAVEN MEDICAL RESEARCH REACTOR

    International Nuclear Information System (INIS)

    Clinical trials of Boron Neutron Capture Therapy for patients with malignant brain tumor had been carried out for half a decade, using an epithermal neutron beam at the Brookhaven's Medical Reactor. The decision to permanently close this reactor in 2000 cut short the efforts to implement a new conceptual design to optimize this beam in preparation for use with possible new protocols. Details of the conceptual design to produce a higher intensity, more forward-directed neutron beam with less contamination from gamma rays, fast and thermal neutrons are presented here for their potential applicability to other reactor facilities. Monte Carlo calculations were used to predict the flux and absorbed dose produced by the proposed design. The results were benchmarked by the dose rate and flux measurements taken at the facility then in use

  17. Design and Fabrication of a Highly Integrated Silicon Detector for the STAR Experiment at Brookhaven National Laboratory

    CERN Document Server

    Buck, Benjamin; Bessuille, Jason; Cepeda, Mario; Johnson, Thomas; Kelsey, James; van Nieuwenhuizen, Gerrit; Visser, Gerard

    2014-01-01

    We present the design of a detector used as a particle tracking device in the STAR experiment at the RHIC collider of Brookhaven National Laboratories. The "stave," 24 of which make up the completed detector, is a highly mechanically integrated design comprised of 6 custom silicon sensors mounted on a Kapton substrate. 4608 wire bonds connect these sensors to 36 analog front-end chips which are mounted on the same substrate. Power and signal connectivity from the hybrid to the front-end chips is provided by wire bonds. The entire circuit is mounted on a carbon fiber base co-cured to the Kapton substrate. We present the unique design challenges for this detector and some novel techniques for overcoming them.

  18. ACCELERATED SITE TECHNOLOGY DEPLOYMENT COST AND PERFORMANCE REPORT COMPARABILITY OF ISOCS INSTRUMENT IN RADIONUCLIDE CHARACTERICATION AT BROOKHAVEN NATIONAL LABORATORY

    Energy Technology Data Exchange (ETDEWEB)

    KALB,P.; LUCKETT,L.; MILLER,K.; GOGOLAK,C.; MILIAN,L.

    2001-03-01

    This report describes a DOE Accelerated Site Technology Deployment project being conducted at Brookhaven National Laboratory to deploy innovative, radiological, in situ analytical techniques. The technologies are being deployed in support of efforts to characterize the Brookhaven Graphite Research Reactor (BGRR) facility, which is currently undergoing decontamination and decommissioning. This report focuses on the deployment of the Canberra Industries In Situ Object Counting System (ISOCS) and assesses its data comparability to baseline methods of sampling and laboratory analysis. The battery-operated, field deployable gamma spectrometer provides traditional spectra of counts as a function of gamma energy. The spectra are then converted to radionuclide concentration by applying innovative efficiency calculations using monte carlo statistical methods and pre-defined geometry templates in the analysis software. Measurement of gamma emitting radionuclides has been accomplished during characterization of several BGRR components including the Pile Fan Sump, Above Ground Ducts, contaminated cooling fans, and graphite pile internals. Cs-137 is the predominant gamma-emitting radionuclide identified, with smaller quantities of Co-60 and Am-241 detected. The Project used the Multi-Agency Radiation Survey and Site Investigation Manual guidance and the Data Quality Objectives process to provide direction for survey planning and data quality assessment. Analytical results have been used to calculate data quality indicators (DQI) for the ISOCS measurements. Among the DQIs assessed in the report are sensitivity, accuracy, precision, bias, and minimum detectable concentration. The assessment of the in situ data quality using the DQIs demonstrates that the ISOCS data quality can be comparable to definitive level laboratory analysis when the field instrument is supported by an appropriate Quality Assurance Project Plan. A discussion of the results obtained by ISOCS analysis of

  19. Complementary tests in the assistance medical practice. Some useful considerations for the professional formation of doctors. Los exámenes complementarios en la práctica médica asistencial. Algunas consideraciones útiles para el médico en formación.

    Directory of Open Access Journals (Sweden)

    Luis Alberto Corona Martínez

    Full Text Available In spite of the present contradictions about the place lab tests have in the medical assistance, to ignore this kind of tests in the medical practice would not be a way to touch the topic objectively. The aim of this article is to present some considerations about the use of lab tests in the medical practice , which are very useful for the new doctors in formations.

    A pesar de la polémica actual sobre el lugar de las pruebas complementarias en la asistencia médica, obviar la importancia de estos exámenes en la práctica médica no sería abordar este tema con objetividad. El propósito de este artículo es exponer algunas consideraciones acerca de la utilización de los exámenes complementarios en la práctica asistencial, lo cual puede ser de utilidad para los médicos en formación.

  20. Optical fiber sensors for medical applications: practical engineering considerations

    NARCIS (Netherlands)

    Heijmans, J.A.C.; Cheng, L.K.; Wieringa, F.P.

    2008-01-01

    The advantages of optical fibers as medical sensors are recognized world wide nowadays. Insensitivity to electromagnetic disturbances and relative small dimensions are the most well known properties. The advantages of fiber optic sensors are especially valuable within environments with high temperat

  1. CONSIDERATIONS ON TOURIST MARKETING THEORY AND PRACTICE IN ROMANIA

    Directory of Open Access Journals (Sweden)

    Erika KULCSÁR

    2012-06-01

    Full Text Available Tourism marketing as a distinct field of marketing services has been and will certainly be a discipline that will be studied in greater depth by experts in this field of great interest. Tourist destinations lead a fierce battle to capture and maintain consumer interest in tourism products and services. For this reason tourist destinations and tourist entities operating in the tourism market should pay special attention to tourism marketing mix elements (product, price, distribution, promotion, people, physical evidence, processes. A key role in assessing the tourism services offered by a certain tourist destination lies with the universities that have as "task" superior human resource training in the tourism sector. This specific element of the tourism marketing mix has a key role in creating the image of tourist destinations.

  2. The theory and practice of privatisation (considerations for Ireland)

    OpenAIRE

    Halford, Robert

    1992-01-01

    Privatisation has become an important political and economic tool. It has been applied worldwide to assist economic growth, to lessen national debts and to free competitive forces. This study examines the theory and application of privatisation. Part One studies the theoretical background. The first chapter explores the arguments for and against its use. The debate on privatisation is largely inconclusive. Its merits and demerits often cancel each other. In Chapter One...

  3. Ethical considerations in dental laser research, education, and practice

    Science.gov (United States)

    Goldstein, Alan T.; Coluzzi, Donald J.; Sulewski, John G.; White, Joel M.

    1995-05-01

    This presentation addresses the interplay between commerce and conscience. The relationship between industry and academia must be free of both true and apparent conflict of interest. Obviously, the matter is of great importance, since as scientists and clinicians, our integrity is our most valuable asset. This is no less true for the manufacturers of dental laser technology. Ethics, then, is a bottom-line issue for all concerned. Often, in spite of good intentions, there has been no clear-cut policy on this issue. Occasionally, when there has been policy, there has been no mechanism for implementation. Universities have conflict-of-interest requirements, while industry and others in the profession do not. In the academic sphere, we are obligated to be open, thorough, honest and scrupulous in our research and educational activities. Recently, the Board of Directors of the Academy of Laser Dentistry unanimously passed a resolution clarifying their position on conflict-of-interest issues. We offer it to SPIE so that ultimately, we may face our profession and business colleagues squarely, and with full and faithful disclosure. Issues of conflict of interest, principal investigators, financial interests, and recommendations for full disclosure are presented.

  4. REVOCATION OF ADMINISTRATIVE ACTS - THEORETICAL AND PRACTICAL CONSIDERATIONS

    Directory of Open Access Journals (Sweden)

    ELENA EMILIA STEFAN

    2011-04-01

    Full Text Available Revocation is a method of terminating the legal effects of an administrative act.Just like the general theory of law admits that any subject of law, author of a manifestation of will, is able to withdraw it, in the administrative law there is also possibility for the authority that issued the administrative act to abrogate its own act under certain circumstances.Thus, this study aims at making a presentation of the legal regime of the revocation of administrative acts, starting from aspects such as terminology, legal grounds, reasons, term, and ending with the analysis of the applicable legislation on revocation, particularly of the law on administrative disputes, and much more. Hence, revocability appears to be the fundamental principle of the legal regime of administrative acts, in close connection with the principle of stability of legal relationships.

  5. Practical Considerations for Using Pooled Lentiviral CRISPR Libraries.

    Science.gov (United States)

    McDade, Joel R; Waxmonsky, Nicole C; Swanson, Lianna E; Fan, Melina

    2016-01-01

    CRISPR/Cas9 technology is ideally suited for genome-wide screening applications due to the ease of generating guide RNAs (gRNAs) and the versatility of Cas9 or Cas9 derivatives to knockout, repress, or activate expression of target genes. Several pooled lentiviral CRISPR libraries have been developed and are now publicly available, but while using CRISPR/Cas9 for genetic experiments has become widely adopted, genome-wide screening experiments remain technically challenging. This review covers the basics of CRISPR/Cas9, describes several publicly available CRISPR libraries, and provides a general protocol for conducting genome-wide screening experiments using CRISPR/Cas9. © 2016 by John Wiley & Sons, Inc. PMID:27366891

  6. Theoretical and practical considerations of measuring extravascular lung water

    International Nuclear Information System (INIS)

    The volume of extravascular lung water is currently measured in vivo from the difference in mean transit times of the extrapolated first-pass dilution curves of two indicators, one diffusible and the other confined to the intravascular space. To overcome the limitations of this method, one can prolong the measurement interval, introduce a highly diffusible indicator, or both. In the first case, recirculating indicators are measured and included in the computation by deconvolution of the mean transit time through the lung. In the second case, heat is used as the water indicator. In the third case, not yet explored, recirculating heat would be measured and long thermal transit times uncovered. In view of the complexity of the deconvolution method and the pitfalls of the thermal dilution method, a radiographic score of pulmonary edema may be more useful clinically to assess the volume of extravascular lung water in patients with heart disease or adult respiratory distress syndrome. 49 references

  7. Theoretical and practical considerations of measuring extravascular lung water

    Energy Technology Data Exchange (ETDEWEB)

    Giuntini, C.; Pistolesi, M.; Miniati, M.; Fazio, F.

    1988-07-01

    The volume of extravascular lung water is currently measured in vivo from the difference in mean transit times of the extrapolated first-pass dilution curves of two indicators, one diffusible and the other confined to the intravascular space. To overcome the limitations of this method, one can prolong the measurement interval, introduce a highly diffusible indicator, or both. In the first case, recirculating indicators are measured and included in the computation by deconvolution of the mean transit time through the lung. In the second case, heat is used as the water indicator. In the third case, not yet explored, recirculating heat would be measured and long thermal transit times uncovered. In view of the complexity of the deconvolution method and the pitfalls of the thermal dilution method, a radiographic score of pulmonary edema may be more useful clinically to assess the volume of extravascular lung water in patients with heart disease or adult respiratory distress syndrome. 49 references.

  8. Dyslexia in general practice education: considerations for recognition and support.

    Science.gov (United States)

    Shrewsbury, Duncan

    2016-07-01

    Dyslexia is a common developmental learning difficulty, which persists throughout life. It is highly likely that those working in primary care will know, or even work with someone who has dyslexia. Dyslexia can impact on performance in postgraduate training and exams. The stereotypical characteristics of dyslexia, such as literacy difficulties, are often not obvious in adult learners. Instead, recognition requires a holistic approach to evaluating personal strengths and difficulties, in the context of a supportive relationship. Strategies to support dyslexic learners should consider recommendations made in formal diagnostic reports, and aim to address self-awareness and coping skills. PMID:27306461

  9. THEORETICAL CONSIDERATIONS AND PRACTICAL APPROACHES FOR CALCULATING IPI AND ICA

    OpenAIRE

    Mircea BURIAN; Diana ASTALÎŞ; Mircea CHIRA; Nina ALEXEVICI

    2010-01-01

    Implementation of the Classification of Activities in the NationalEconomy revision 2 (CANE – Rev.2) in industrial statistics domain, raised a number of technical and methodological issues with complex implications in determining the industrial production index (IPI) and respectively of turnover index in industry (ICA) both at the national level and especially at the territorial level /county level. This is due to the large volume of processed data in terms of the adoption of 2005 as base year...

  10. Policies to Enable Bioenergy Deployment: Key Considerations and Good Practices

    Energy Technology Data Exchange (ETDEWEB)

    Smolinksi, Sharon [National Renewable Energy Lab. (NREL), Golden, CO (United States); Cox, Sadie [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2016-05-01

    Bioenergy is renewable energy generated from biological source materials, and includes electricity, transportation fuels and heating. Source materials are varied types of biomass, including food crops such as corn and sugarcane, non-edible lignocellulosic materials such as agricultural and forestry waste and dedicated crops, and municipal and livestock wastes. Key aspects of policies for bioenergy deployment are presented in this brief as part of the Clean Energy Solutions Center's Clean Energy Policy Brief Series.

  11. Practical considerations for addressing uncertainties in monitoring bulk deposition

    International Nuclear Information System (INIS)

    The assessment of the deposition of both wet (rain and cloud) and dry sedimenting particles is a prerequisite for estimating element fluxes in ecosystem research. Many nations and institutions operate deposition networks using different types of sampler. However, these samplers have rarely been characterized with respect to their sink properties. Major errors in assessing bulk deposition can result from poor sampling properties and defective sampling strategies. Relevant properties are: sampler geometry and material, in particular the shape of the rim; sink properties for gases and aerosols; and microbial transformations of the collected samples. An adequate number of replicates allows the identification of samples which are contaminated, in particular by bird droppings. The paper discusses physical and chemical properties of the samplers themselves. The dependence of measurement accuracy on the number of replicates and the sampling area exposed is discussed. Recommendations are given for sampling strategies, and for making corrections and substitution of missing data. - Recommendations are given for sampling strategies and for making corrections and substitution of missing data

  12. Vitamin Requirements and Deficiencies: Theoretical and Practical Considerations for Athletes.

    Science.gov (United States)

    Sirota, Lorraine

    1991-01-01

    Research indicates athletes may require more of certain nutrients than other healthy individuals. The article discusses vitamin requirements and deficiencies and how to supply the needed nutrients. Since coaches, trainers, and physical education teachers influence their athletes' behaviors, they must examine the issues associated with vitamin…

  13. On-chip antenna: Practical design and characterization considerations

    KAUST Repository

    Shamim, Atif

    2012-07-28

    This paper highlights the challenges of an emergent field, namely, on-chip antenna design. Consistent with the RF System-on-Chip (SoC) concept, co-design strategy for circuits and on-chip antennas is described. A number of design and layout issues, arising from the highly integrated nature of this kind of systems, are discussed. The characterization difficulties related to on-chip antennas radiation properties are also highlighted. Finally, a novel on-wafer test fixture is proposed to measure the gain and radiation pattern of the on-chip antennas in the anechoic chamber.

  14. Feed-in Tariffs: Good Practices and Design Considerations

    Energy Technology Data Exchange (ETDEWEB)

    Cox, Sadie [National Renewable Energy Lab. (NREL), Golden, CO (United States); Esterly, Sean [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2016-01-02

    In recent years, feed-in tariff (FIT) activity has focused primarily on revisions to current policies, underscoring the need for stable and predictable, yet flexible, policy environments. This policy brief provides a primer on key FIT design elements, lessons from country experience, and support resources to enable more detailed and country-specific FIT policy design.

  15. DNA methylation based biomarkers: Practical considerations and applications

    DEFF Research Database (Denmark)

    Nielsen, Helene Myrtue; How Kit, Alexandre; Tost, Jorg

    2012-01-01

    biochemical molecules such as proteins, DNA, RNA or lipids, whereby protein biomarkers have been the most extensively studied and used, notably in blood-based protein quantification tests or immunohistochemistry. The rise of interest in epigenetic mechanisms has allowed the identification of a new type of...... specific and sensitive than commonly used protein biomarkers, which could clearly justify their use in clinics. However, very few of them are at the moment used in clinics and even less commercial tests are currently available. The objective of this review is to discuss the advantages of DNA methylation as...... biomarker, DNA methylation, which is of great potential for many applications. This stable and heritable covalent modification mostly affects cytosines in the context of a CpG dinucleotide in humans. It can be detected and quantified by a number of technologies including genome-wide screening methods as...

  16. Practical clinical considerations of luting cements: A review

    OpenAIRE

    Lad, Pritam P; Kamath, Maya; Tarale, Kavita; Kusugal, Preethi B

    2014-01-01

    The longevity of fixed partial denture depends on the type of luting cement used with tooth preparation. The clinician’s understating of various cements, their advantages and disadvantages is of utmost importance. In recent years, many luting agents cements have been introduced claiming clinically better performance than existing materials due to improved characteristics. Both conventional and contemporary dental luting cements are discussed here. The various agents discussed are: Zinc pho...

  17. Electromyography in musculoskeletal pain: A reappraisal and practical considerations

    Directory of Open Access Journals (Sweden)

    R P Lazaro

    2015-01-01

    Conclusions: Use of EMG in the diagnosis of local MSP, unless associated with clinical neurologic deficits, almost always yields negative results. The utility of this procedure is limited to pathology in the motor unit. It cannot assess the function of the sensory components of the spinal roots, small-diameter sensory nerves, and the sensory innervation of the spine via sinuvertebral nerve. Therefore, if the motor unit is anatomically and physiologically intact, the procedure is of little value in the diagnosis of MSP. Likewise, peripheral nerve conduction study is likely to be normal unless clear neurologic deficits are present. The present study illustrates that a good history and meticulous neurologic examination should be an integral part of an ideal electrodiagnostic procedure.

  18. Infasurf and Curosurf: Theoretical and Practical Considerations with New Surfactants

    OpenAIRE

    Nguyen, Thuy N.; Cunsolo, Stephanie M.; Gal, Peter; Ransom, J. Laurence

    2003-01-01

    Type II pneumocytes, normally responsible for surfactant production and release, are insufficiently formed and differentiated in the premature infant born before 34 weeks' gestation. Without an adequate amount of pulmonary surfactant, alveolar surface tension increases, leading to collapse and decreased lung compliance. Pulmonary surfactants are naturally occurring substances made of lipids and proteins. They lower surface tension at the interface between the air in the lungs, specifically at...

  19. Analysing Existing Datasets: Some Considerations Arising from Practical Experience

    Science.gov (United States)

    Yorke, Mantz

    2011-01-01

    Data that have been collected for specific purposes may be exploited in the service of other interests (such as institutional research), though the exploitation may have to be accompanied by methodological compromises of various kinds. As a consequence, the findings might satisfy the criterion of being "good enough" for the purposes of practical…

  20. Practical considerations for ventilating calf barns in winter.

    Science.gov (United States)

    Nordlund, Kenneth V

    2008-03-01

    The use of air sampling devices to measure the concentrations of airborne bacteria in clinical investigations and research trials in calf barns has indicated that traditional systems of ventilation are problematic in cold weather. Individual pen designs should have two solid sides, but the front and rear should be as open as possible. Thermal stress should be managed by providing deep bedding and not by enclosing the pen. Air hygiene can be improved by reducing stocking density and using supplemental positive-pressure ventilation systems to deliver small amounts of air to each pen. Implementation of these recommendations can produce calf barns that seem to equal calf hutches in minimizing disease and provide better working conditions for the caregivers. PMID:18299031

  1. Scale and Governance: Conceptual Considerations and Practical Implications

    NARCIS (Netherlands)

    Kok, K.; Veldkamp, T.

    2011-01-01

    Policies have many unforeseen impacts on social-ecological systems at different levels of spatial and temporal scales. Partly because of this, both scale and governance have been and continue to be hotly debated and studied topics within many scientific disciplines. Although there are two distinct v

  2. Education and Development: Twelve Considerations for Transformative Practice

    Science.gov (United States)

    VanBalkom, W. Duffie; Eastham, Sarada

    2011-01-01

    Twelve factors that are essential to consider when embarking on the process of transformative development are examined in the context of international development programming in education and training. Each factor raises a number of questions for the deliberations of policy makers, development practitioners, scholars, international educators,…

  3. Practical considerations for addressing uncertainties in monitoring bulk deposition

    Energy Technology Data Exchange (ETDEWEB)

    Erisman, J.W. [ECN Clean Fossil Fuels, Petten (Netherlands); Daemmgen, U. [Institute of Agroecology, Federal Agricultural Research Centre, Braunschweig (Germany); Cape, J.N.; Fowler, D. [Centre for Ecology and Hydrology, Bush Estate, Penicuik, Scotland (United Kingdom); Gruenhage, L. [Institute for Plant Ecology, Justus-Liebig-University, Giessen (Germany)

    2005-03-01

    The assessment of the deposition of both wet (rain and cloud) and dry sedimentation particles is a prerequisite for estimating element fluxes in ecosystem research. Many nations and institutions operate deposition networks using different types of sampler. However, these samplers have rarely been characterized with respect to their sink properties. Major errors in assessing bulk deposition can result from poor sampling properties and defective sampling strategies. Relevant properties are: sampler geometry and material, in particular the shape of the rim; sink properties for gases and aerosols; and microbial transformations of the collected samples. An adequate number of replicates allows the identification of samples which are contaminated, in particular by bird droppings. The paper discusses physical and chemical properties of the samplers themselves. The dependence of measurement accuracy on the number of replicates and the sampling area exposed is discussed. Recommendations are given for sampling strategies, and for making corrections and substitution of missing data. Recommendations are given for sampling strategies and for making corrections and substitution of missing data.

  4. Practical considerations for addressing uncertainties in monitoring bulk deposition

    Energy Technology Data Exchange (ETDEWEB)

    Daemmgen, Ulrich [Institute of Agroecology, Federal Agricultural Research Centre, Bundesallee 50, D-38116 Braunschweig (Germany)]. E-mail: ulrich.daemmgen@fal.de; Erisman, Jan Willem [Netherlands Energy Research Foundation ECN, P.O. Box 1, NL-1755 ZG Petten (Netherlands); Cape, J. Neil [Centre for Ecology and Hydrology, Bush Estate, Penicuik EH26 0QB, Scotland (United Kingdom); Gruenhage, Ludger [Institute for Plant Ecology, Justus-Liebig-University, Heinrich-Buff-Ring 26-32, D-35392 Giessen (Germany); Fowler, David [Centre for Ecology and Hydrology, Bush Estate, Penicuik EH26 0QB, Scotland (United Kingdom)

    2005-04-01

    The assessment of the deposition of both wet (rain and cloud) and dry sedimenting particles is a prerequisite for estimating element fluxes in ecosystem research. Many nations and institutions operate deposition networks using different types of sampler. However, these samplers have rarely been characterized with respect to their sink properties. Major errors in assessing bulk deposition can result from poor sampling properties and defective sampling strategies. Relevant properties are: sampler geometry and material, in particular the shape of the rim; sink properties for gases and aerosols; and microbial transformations of the collected samples. An adequate number of replicates allows the identification of samples which are contaminated, in particular by bird droppings. The paper discusses physical and chemical properties of the samplers themselves. The dependence of measurement accuracy on the number of replicates and the sampling area exposed is discussed. Recommendations are given for sampling strategies, and for making corrections and substitution of missing data. - Recommendations are given for sampling strategies and for making corrections and substitution of missing data.

  5. Practical considerations for adaptive trial design and implementation

    CERN Document Server

    Pinheiro, José; Kuznetsova, Olga

    2014-01-01

    This edited volume is a definitive text on adaptive clinical trial designs from creation and customization to utilization. As this book covers the full spectrum of topics involved in the adaptive designs arena, it will serve as a valuable reference for researchers working in industry, government and academia. The target audience is anyone involved in the planning and execution of clinical trials, in particular, statisticians, clinicians, pharmacometricians, clinical operation specialists, drug supply managers, and infrastructure providers.  In spite of the increased efficiency of adaptive trials in saving costs and time, ultimately getting drugs to patients sooner, their adoption in clinical development is still relatively low.  One of the chief reasons is the higher complexity of adaptive design trials as compared to traditional trials. Barriers to the use of clinical trials with adaptive features include the concerns about the integrity of study design and conduct, the risk of regulatory non-acceptance, t...

  6. Renewable Electricity Standards: Good Practices and Design Considerations

    Energy Technology Data Exchange (ETDEWEB)

    Cox, Sadie [National Renewable Energy Lab. (NREL), Golden, CO (United States); Esterly, Sean [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2016-01-02

    In widespread use globally, renewable electricity standards (RES) are one of the most widely adopted renewable energy policies and a critical regulatory vehicle to accelerate renewable energy deployment. This policy brief provides an introduction to key RES design elements, lessons from country experience, and support resources to enable more detailed and country-specific RES policy design.

  7. CONSIDERATIONS ON TOURIST MARKETING THEORY AND PRACTICE IN ROMANIA

    OpenAIRE

    Erika KULCSÁR

    2012-01-01

    Tourism marketing as a distinct field of marketing services has been and will certainly be a discipline that will be studied in greater depth by experts in this field of great interest. Tourist destinations lead a fierce battle to capture and maintain consumer interest in tourism products and services. For this reason tourist destinations and tourist entities operating in the tourism market should pay special attention to tourism marketing mix elements (product, price, distribution, promotion...

  8. The LMS Selection Process: Practices and Considerations. ECAR Research Bulletin

    Science.gov (United States)

    Cavanagh, Thomas B.

    2014-01-01

    With more than 80% of institutions offering online learning options and even more using web technologies to enhance traditional classroom instruction, the learning management system (LMS) is increasingly an indispensable, enterprise-level technology for today's colleges and universities. Naturally, each institution has a unique set of…

  9. Practical considerations of pyrite oxidation control in uranium tailings

    International Nuclear Information System (INIS)

    The problems posed by the oxidation of pyrite in uranium tailings include the generation of sulfuric acid and acid sulfate metal salts. These have substantial negative impacts on watercourse biota by themselves, and the lowered pH levels tend to mobilize heavy metals present in the tailings the rate of oxidation of pyrite at lower pH levels is catalyzed by sulfur and iron oxidizing bacteria present in soils. No single clear solution to the problems came from this study. Exclusion of air is a most important preventative of bacterial catalysis of oxidation. Bactericides, chemically breaking the chain of integrated oxidation reactions, maintaining anaerobic conditions, or maintaining a neutral or alkaline pH all reduce the oxidation rate. Removal of pyrite by flotation will reduce but not eliminate the impact of pyrite oxidation. Controlled oxidation of the remaining sulfide in the flotation tails would provide an innocuous tailing so far as acidity generation is concerned

  10. Brain imaging and psychotherapy: methodological considerations and practical implications.

    Science.gov (United States)

    Linden, David E J

    2008-11-01

    The development of psychotherapy has been based on psychological theories and clinical effects. However, an investigation of the neurobiological mechanisms of psychological interventions is also needed in order to improve indication and prognosis, inform the choice of parallel pharmacotherapy, provide outcome measures and potentially even aid the development of new treatment protocols. This neurobiological investigation can be informed by animal models, for example of learning and conditioning, but will essentially need the non-invasive techniques of functional neuroimaging in order to assess psychotherapy effects on patients' brains, which will be reviewed here. Most research so far has been conducted in obsessive compulsive disorder (OCD), anxiety disorders and depression. Effects in OCD were particularly exciting in that both cognitive behavioural therapy and medication with a selective serotonin inhibitor led to a reduction in blood flow in the caudate nucleus. In phobia, brief courses of behavioural therapy produced marked reductions of paralimbic responses to offensive stimuli in line with the clinical improvement. Findings in depression are less consistent, with both increases and decreases in prefrontal metabolism being reported. However, they are important in pointing to different mechanisms for the clinical effects of pharmacotherapy (more "bottom up") and psychotherapy (more "top down"). For the future it would be desirable if the findings of psychotherapy changes to brain activation patterns were confirmed in larger groups with homogenous imaging protocols. Functional imaging has already made great contributions to the understanding of the neural correlates of psychopathology. For example, evidence converges to suggest that the subgenual cingulate is crucial for mood regulation. One current clinical application of these findings is deep brain stimulation in areas highlighted by such imaging studies. I will discuss their initial application in depression and OCD, and suggest potential alternative options based on recent developments in neurofeedback technology. PMID:18985299

  11. Psychotropic Medications in Autism: Practical Considerations for Parents

    Science.gov (United States)

    Williamson, Edwin D.; Martin, Andres

    2012-01-01

    Medications are widely prescribed in children with autism spectrum disorders. Most commonly these medications are used to decrease symptoms that fall under three main clusters: irritability, ADHD-like symptoms, and repetitive behaviors. In this guide we introduce basic approaches to medications in children with autism and review the scientific…

  12. Sprint Running Performance Monitoring: Methodological and Practical Considerations.

    Science.gov (United States)

    Haugen, Thomas; Buchheit, Martin

    2016-05-01

    The aim of this review is to investigate methodological concerns associated with sprint performance monitoring, more specifically the influence and magnitude of varying external conditions, technology and monitoring methodologies not directly related to human physiology. The combination of different starting procedures and triggering devices can cause up to very large time differences, which may be many times greater than performance changes caused by years of conditioning. Wind, altitude, temperature, barometric pressure and humidity can all combine to yield moderate time differences over short sprints. Sprint performance can also be affected by the athlete's clothing, principally by its weight rather than its aerodynamic properties. On level surfaces, the track compliance must change dramatically before performance changes larger than typical variation can be detected. An optimal shoe bending stiffness can enhance performance by a small margin. Fully automatic timing systems, dual-beamed photocells, laser guns and high-speed video are the most accurate tools for sprint performance monitoring. Manual timing and single-beamed photocells should be avoided over short sprint distances (10-20 m) because of large absolute errors. The validity of today's global positioning systems (GPS) technology is satisfactory for long distances (>30 m) and maximal velocity in team sports, but multiple observations are still needed as reliability is questionable. Based on different approaches used to estimate the smallest worthwhile performance change and the typical error of sprint measures, we have provided an assessment of the usefulness of speed evaluation from 5 to 40 m. Finally, we provide statistical guidelines to accurately assess changes in individual performance; i.e. considering both the smallest worthwhile change in performance and the typical error of measurement, which can be reduced while repeating the number of trials. PMID:26660758

  13. Analysis of reactor cavity radiation streaming: some practical considerations

    International Nuclear Information System (INIS)

    A description is presented of a cost effective analysis procedure for use in the prediction of radiation environments in the cavity and containment building of a nuclear power reactor. Comments are offered on potential problems in certification of analysis procedures and the availability of benchmarkable data sets, both measurements and calculations

  14. Endodontic Considerations in Three-canalled Premolars: A Practical Update.

    Science.gov (United States)

    Mohammadi, Zahed; Shalavi, Sousan; Giardino, Luciano; Asgary, Saeed

    2016-01-01

    The most difficult clinical considertions in orthograde root canal treatment are generally related to the anatomy of the teeth. Three-canalled maxillary and mandibular premolars (mini-molars) have been reported in several studies. The purpose of this paper was to review various aspects of three-canalled premolars including incidence, clinical and radiographic diagnosis, racial predisposition, access cavity preparation, instrumentation and obturation. PMID:27141223

  15. Nutritional Considerations for the Overweight Young Athlete.

    Science.gov (United States)

    Chu, Lisa; Timmons, Brian W

    2015-11-01

    Nutritional considerations for the overweight young athlete have not been thoroughly discussed in the scientific literature. With the high prevalence of childhood obesity, more children participating in sports are overweight or obese. This is particularly true for select sports, such as American football, where large size provides an added advantage. While sport participation should be encouraged because of the many benefits of physical activity, appropriate nutritional practices are vital for growth, and optimizing performance and health. The overweight young athlete may face certain challenges because of variable energy costs and nutrient requirements for growth and routine training, compared with nonoverweight athletes. Special attention should be given to adopting healthy lifestyle choices to prevent adverse health effects due to increased adiposity. In this review, we aim to discuss special nutritional considerations and highlight gaps in the literature concerning nutrition for overweight young athletes compared with their nonoverweight peers. PMID:26251973

  16. Ethical Considerations in Technology Transfer.

    Science.gov (United States)

    Froehlich, Thomas J.

    1991-01-01

    Examines ethical considerations involved in the transfer of appropriate information technology to less developed countries. Approaches to technology are considered; two philosophical frameworks for studying ethical considerations are discussed, i.e., the Kantian approach and the utilitarian perspective by John Stuart Mill; and integration of the…

  17. Advanced LBB methodology and considerations

    Energy Technology Data Exchange (ETDEWEB)

    Olson, R.; Rahman, S.; Scott, P. [Battelle, Columbus, OH (United States)] [and others

    1997-04-01

    LBB applications have existed in many industries and more recently have been applied in the nuclear industry under limited circumstances. Research over the past 10 years has evolved the technology so that more advanced consideration of LBB can now be given. Some of the advanced considerations for nuclear plants subjected to seismic loading evaluations are summarized in this paper.

  18. Justification and radiology: Some ethical considerations

    International Nuclear Information System (INIS)

    This paper, which seeks to address the issue of justification in radiology, intends firstly to comment on the current discussion of the ethical foundation of radiological practice that focuses on the move from utilitarianism to the rights-centred criterion. Secondly, and this constitutes the bulk of the paper, it aims to offer a philosophical perspective, which is hoped will lead to a consideration of certain specific areas in ethical decision-making in the attempts here to deal with the main issue of justification in radiology. (authors)

  19. Some Considerations in Designing a GPS Pseudolite

    Science.gov (United States)

    Rapinski, J.; Koziar, M.; Rzepecka, Z.; Cellmer, S.; Chrzanowski, A.

    2012-01-01

    Pseudolites are transmitters of GPS-like signals placed on the ground. Though pseudolites are well known devices and have already been used in the project where visibility to the GNSS satellites is limited, there are still many issues that need enhancement. A prototype of a low-cost pseudolite is being designed and assembled at the University of Warmia and Mazury. This will allow for conducting tests with various codes, signals and software. The goal of the project is to apply the pseudolite as an augmentation to GNSS positioning tasks in geodetic engineering projects. Some practical considerations crucial for the design are discussed in this paper.

  20. PROJECT-SPECIFIC TYPE A VERIFICATION FOR THE HIGH FLUX BEAM REACTOR UNDERGROUND UTILITIES REMOVAL PHASE 2 D/F WASTE LINE REMOVAL, BROOKHAVEN NATIONAL LABORATORY UPTON, NEW YORK

    International Nuclear Information System (INIS)

    Oak Ridge Institute for Science and Education (ORISE) has reviewed the project documentation and data for the High Flux Beam Reactor (HFBR) Underground Utilities removal Phase 2; the D/F Waste Line removal at Brookhaven National Laboratory (BNL) in Upton, New York. The Brookhaven Survey Group (BSG) has completed removal and performed the final status survey (FSS) of the D/F Waste Line that provided the conduit for pumping waste from Building 750 to Building 801. Sample results have been submitted as required to demonstrate that the cleanup goals of 15 mrem/yr above background to a resident in 50 years have been met. Four rounds of sampling, from pre-excavation to final status survey (FSS), were performed as specified in the Field Sampling Plan (FSP) (BNL 2010a). It is the policy of the US Departmental of Energy (DOE) to perform independent verifications of decontamination and decomissioning activities conducted at DOE facilities. ORISE has been designated as the organization responsible for this task at the HFBR. ORISE together with DOE determined that a Type A verification of the D/F Waste Line was appropriate based on its method of construction and upon the minimal potential for residual radioactivity in the area. The removal of underground utilities is being performed in three stages in the process to decommission the HFBR facility and support structures. Phase 2 of this project included the grouting and removal of 1100 feet of 2-inch pipe and 640 feet of 4-inch pipe that served as the D/F Waste Line. Based on the pre-excavation sample results of the soil overburden, the potential for contamination of the soil surrounding the pipe is minimal (BNL 2010a). ORISE reviewed the BNL FSP and identified comments for consideration (ORISE 2010). BNL prepared a revised FSP that addressed each ORISE comment adequately (BNL 2010a). ORISE referred to the revised Phase 2 D/F Waste Line removal FSP FSS data to conduct the Type A verification and determine whether the intent odf

  1. Structural sizing considerations for large space platforms

    Science.gov (United States)

    Heard, W. L., Jr.; Bush, H. G.; Walz, J. E.; Rehder, J. J.

    1980-01-01

    Structural optimization studies are made using mathematical programming techniques to examine minimum mass structural proportions of deployable and erectable tetrahedral truss platforms subject to the integrated effects of practical design requirements. Considerations integrated into the optimization process are: 1) lowest natural frequencies of the platform and individual platform components (struts); 2) packaging constraints imposed by the Shuttle cargo bay capacity; 3) initial curvature of the struts; 4) column buckling of the struts due to gravity gradient, orbital transfer, strut length tolerance, or design loads; and 5) practical lower limits for strut diameter and wall thickness. Ultra-low mass designs are shown to be possible with strut proportions much more slender than those conventionally used for earthbound application.

  2. Ethical considerations in cardiovascular prevention.

    Science.gov (United States)

    Follath, F

    2009-12-01

    patients and healthy subjects for the general population seen in everyday practice? Increasingly, the economic aspects of long-term prevention and problems of a fair allocation of limited healthcare resources are also important issues giving rise to contrasting views among patients, doctors, insurance providers and politicians. What are the priorities and who should decide? Ethical considerations relating to the above questions in CV prevention are discussed in this article. PMID:19500153

  3. Utility considerations for tritium production

    International Nuclear Information System (INIS)

    The Southern Nuclear Company has a long-standing commitment to nuclear power and is interested in pursuing the possible use of one of its existing commercial reactors as an alternative for reinitiating the production of tritium to support the nation's defense program requirements. We understand that Congress and the administration agree on the need to replenish the nation's supply of tritium and that a number of production options are under consideration. This paper discusses the financial considerations, legal and regulatory considerations for the production of tritium utilizing a commercial power reactor

  4. Regulatory Considerations in Toxicological Neuropathology

    Science.gov (United States)

    Pathological assessment of the nervous system is included in several US Environmental Protection Agency [US EPA or Agency] and Organization for Economic Cooperation and Development [OECD] testing guidelines for health effects of chemicals. A variety of considerations are importan...

  5. Type A Verification Report For The High Flux Beam Reactor Stack And Grounds, Brookhaven National Laboratory, Upton, New York DCN: 5098-SR-08-0

    International Nuclear Information System (INIS)

    The U.S. Department of Energy (DOE) Order 458.1 requires independent verification (IV) of DOE cleanup projects (DOE 2011). The Oak Ridge Institute for Science and Education (ORISE) has been designated as the responsible organization for IV of the High Flux Beam Reactor (HFBR) Stack and Grounds area at Brookhaven National Laboratory (BNL) in Upton, New York. The IV evaluation may consist of an in-process inspection with document and data reviews (Type A Verification) or a confirmatory survey of the site (Type B Verification). DOE and ORISE determined that a Type A verification of the documents and data for the HFBR Stack and Grounds: Survey Units (SU) 6, 7, and 8 was appropriate based on the initial survey unit classification, the walkover surveys, and the final analytical results provided by the Brookhaven Science Associates (BSA).

  6. Considerable Life Extension versus Immortality

    OpenAIRE

    Rosa Rantanen

    2012-01-01

    The ethical desirability of considerable life extension by medical technology has become an increasingly discussed topic in bioethics during recent years. Immortality can be seen as a maximum of life extension. Because of this, many authors use the term 'immortality' for referring to a lifespan that is considerably longer than our current one. However, being literally immortal would be very different from living for hundreds, or even thousands, of years. The arguments that have been made abou...

  7. NUTRITION CONSIDERATIONS IN FOOD SELECTION

    OpenAIRE

    Rimal, Arbindra; Fletcher, Stanley M.; McWatters, Kay H.

    2000-01-01

    The importance of nutrition consideration to households in food selection is instrumental in the development of information programs to promote public health and to market healthy food. Using a national telephone survey of 2880 U.S. households, this study examines the role and influence of socio-economic characteristics and lifestyle on a household meal plannerÂ’s consideration of four dietary components in food selection. Household income, children in households, geographic location, and gen...

  8. The Value of Literacy Practices

    OpenAIRE

    Esposito, Lucio; Kebede, Bereket; Maddox, Bryan

    2015-01-01

    The concepts of literacy events and practices have received considerable attention in educational research and policy. In comparison, the question of value, that is, ‘which literacy practices do people most value?’ has been neglected. With the current trend of cross-cultural adult literacy assessment, it is increasingly important to recognise locally valued literacy practices. In this paper we argue that measuring preferences and weighting of literacy practices provides an empirical and democ...

  9. Deadline pressure and human error: a study of human failures on a particle accelerator at Brookhaven National Laboratory

    International Nuclear Information System (INIS)

    The decline in industrial efficiency may be linked to decreased reliability of complex automatic systems. This decline threatens the viability of complex organizations in industrialized economies. Industrial engineering techniques that minimize system failure by increasing the reliability of systems hardware are well developed in comparison with those available to reduce human operator errors. The problem of system reliability and the associated costs of breakdown can be reduced if we understand how highly skilled technical personnel function in complex operations and systems. The purpose of this research is to investigate how human errors are affected by deadline pressures, technical communication and other socio-dynamic factors. Through the analysis of a technologically complex particle accelerator prototype at Brookhaven National Laboratory, two failure mechanisms: (1) physical defects in the production process and (2) human operator errors were identified. Two instruments were used to collect information on human failures: objective laboratory data and a human failure questionnaire. The results of human failures from the objective data were used to test for the deadline hypothesis and also to validate the human failure questionnaire. To explain why the human failures occurred, data were collected from a four-part, closed choice questionnaire administered to two groups of scientists, engineers, and technicians, working together against a deadline to produce an engineering prototype of a particle accelerator

  10. Magnetic measurements of permanent magnet insertion devices at the BNL-NSLS [Brookhaven National Laboratory--National Synchrotron Light Source

    International Nuclear Information System (INIS)

    Since June 1988, three permanent magnet insertion devices of the hybrid type have been installed into the x-ray ring at the National Synchrotron Light Source at Brookhaven National Lab. as part of the Phase II facility upgrade. The three magnets consist of a soft x-ray undulator (SXU) and two hybrid wigglers, with peak fields of 0.35 and 1.2 Tesla respectively. The SXU magnet has iron poles, samarium cobalt permanent magnets, 80mm period length, 77 poles, and a gap range of 31--100 mm. For this gap range the undulator parameter K, where K = 0.934 B(Tesla)λ(cm), ranges from 2.6 to 0.15. The hybrid wigglers have vanadium pomander poles, samarium cobalt magnets, 120MM periods, 31 poles, and a gap range of 22--122mm. For this gap range K ranges from 13.0 to 0.5. All three of these magnets have electromagnetic coils which can be powered to adjust the value of the magnet field integral. Both point and integral magnetic measurements were performed on these magnets; some of the measurement results will be presented in this paper

  11. THE RELATIVISTIC HEAVY ION COLLIDER (RHIC) REFRIGERATOR SYSTEM AT BROOKHAVEN NATIONAL LABORATORY: SYSTEM PERFORMANCE AND OPERATIONS UPGRADES FOR 2003

    International Nuclear Information System (INIS)

    The main function of the RHIC cryogenic system is to maintain the superconducting magnets in the two rings of the new collider-accelerator at Brookhaven National Laboratory at or below 4.5K. The main feature in the RHIC cryogenic system is the helium refrigerator. A new process control philosophy was implemented that allows this system to track the actual load from the accelerator rings and lets it respond accordingly. The refrigerator capacity decreases as the load decreases and increases as the load increases. This has resulted in the following improvements in the operation of the system: (1) Higher reliability because the rotating equipment does not have to run at full load continuously. (2) Greater stability because the system tracks the load continuously and responds quickly to any transients such as a quench. (3) Reduced power consumption because the discharge pressure of the system is adjusted continuously to match the load; therefore, the compressors draw less power when the load fi-om the accelerator rings decreases. This paper also addresses other modifications introduced that added to the efficiency, stability, and reliability of the system. As a result of this upgrade the Carnot efficiency of the refrigerator system has increased to 15% from around 10%

  12. The NASA Space Radiation Laboratory at Brookhaven National Laboratory: Preparation and delivery of ion beams for space radiation research

    International Nuclear Information System (INIS)

    The NASA Space Radiation Laboratory (NSRL) at Brookhaven National Laboratory (BNL) was commissioned in October 2002 and became operational in July 2003. The NSRL was constructed in collaboration with NASA for the purpose of performing space radiation research as part of the NASA space program. The NSRL can accept a wide variety of ions from BNL's Collider Accelerator Department (CAD) Booster accelerator. These ion beams are extracted from the accelerator with kinetic energies ranging from 0.05 to 3 GeV/nucleon. Many different beam conditions have been produced for experiments at NSRL. The facilities at BNL and the design of the NSRL facility permit a wide variety of beams to be produced with a great degree of flexibility in the delivery of ion beams to experiments. In this report we will describe the facility and its performance over the eight experimental run periods that have taken place since it became operational. We will also describe the current and future capabilities of the NSRL.

  13. Comparative Analysis of Brookhaven National Laboratory Nuclear Decay Data and Super-Kamiokande Neutrino Data: Indication of a Solar Connection

    CERN Document Server

    Sturrock, P A

    2015-01-01

    An experiment carried out at the Brookhaven National Laboratory from February 1982 to December 1989 acquired 364 measurements of the beta-decay rates of a sample of 36Cl and of a sample of 32Si. The experimenters reported finding small periodic annual deviations of the data points from an exponential decay - of uncertain origin. We here analyze this dataset by power spectrum analysis and by forming spectrograms and phasegrams. We confirm the occurrence of annual oscillations but we also find evidence of oscillations in a band of frequencies appropriate for the internal rotation of the Sun. Both datasets show clear evidence of a transient oscillation with a frequency of 12.7 cycles per year that falls in the range of rotational frequencies for the solar radiative zone. We repeat these analyses for 358 neutrino measurements acquired by Super-Kamiokande over the interval May 1986 to August 2001. Spectrogram analysis yields a strong and steady oscillation at about 9.5 cycles per year and an intermittent oscillati...

  14. Design of a high-flux epithermal neutron beam using 235U fission plates at the Brookhaven Medical Research Reactor.

    Science.gov (United States)

    Liu, H B; Brugger, R M; Rorer, D C; Tichler, P R; Hu, J P

    1994-10-01

    Beams of epithermal neutrons are being used in the development of boron neutron capture therapy for cancer. This report describes a design study in which 235U fission plates and moderators are used to produce an epithermal neutron beam with higher intensity and better quality than the beam currently in use at the Brookhaven Medical Research Reactor (BMRR). Monte Carlo calculations are used to predict the neutron and gamma fluxes and absorbed doses produced by the proposed design. Neutron flux measurements at the present epithermal treatment facility (ETF) were made to verify and compare with the computed results where feasible. The calculations indicate that an epithermal neutron beam produced by a fission-plate converter could have an epithermal neutron intensity of 1.2 x 10(10) n/cm2.s and a fast neutron dose per epithermal neutron of 2.8 x 10(-11) cGy.cm2/nepi plus being forward directed. This beam would be built into the beam shutter of the ETF at the BMRR. The feasibility of remodeling the facility is discussed. PMID:7869995

  15. PROJECT-SPECIFIC TYPE A VERIFICATION FOR THE HIGH FLUX BEAM REACTOR UNDERGROUND UTILITIES REMOVAL PHASE 3 TRENCH 1, BROOKHAVEN NATIONAL LABORATORY UPTON, NEW YORK

    International Nuclear Information System (INIS)

    The Oak Ridge Institute for Science and Education (ORISE) has reviewed the project documentation and data for the High Flux Beam Reactor (HFBR) Underground Utilities removal Phase 3; Trench 1 at Brookhaven National Laboratory (BNL) in Upton, New York. The Brookhaven Survey Group (BSG) has completed removal and performed Final Status Survey (FSS) of the 42-inch duct and 14-inch line in Trench 1 from Building 801 to the Stack. Sample results have been submitted as required to demonstrate that the cleanup goal of (le)15 mrem/yr above background to a resident in 50 years has been met. Four rounds of sampling, from pre-excavation to FSS, were performed as specified in the Field Sampling Plan (FSP) (BNL 2010a). It is the policy of the U.S. Department of Energy (DOE) to perform independent verifications of decontamination and decommissioning activities conducted at DOE facilities. ORISE has been designated as the organization responsible for this task for the HFBR Underground Utilities. ORISE, together with DOE, determined that a Type A verification of Trench 1 was appropriate based on recent verification results from Trenches 2, 3, 4, and 5, and the minimal potential for residual radioactivity in the area. The removal of underground utilities has been performed in three stages to decommission the HFBR facility and support structures. Phase 3 of this project included the removal of at least 200 feet of 36-inch to 42-inch duct from the west side to the south side of Building 801, and the 14-inch diameter Acid Waste Line that spanned from 801 to the Stack within Trench 1. Based on the pre-excavation sample results of the soil overburden, the potential for contamination of the soil surrounding the pipe is minimal (BNL 2010a). ORISE reviewed the gamma spectroscopy results for 14 FSS soil samples, four core samples, and one duplicate sample collected from Trench 1. Sample results for the radionuclides of concern were below the established cleanup goals. However, in sample PH-3

  16. Evidence based practice

    DEFF Research Database (Denmark)

    Hjørland, Birger

    2011-01-01

    Evidence-based practice (EBP) is an influential interdisciplinary movement that originated in medicine as evidence-based medicine (EBM) about 1992. EBP is of considerable interest to library and information science (LIS) because it focuses on a thorough documentation of the basis for the decision...

  17. Chernobyl - considerations of an insurer

    International Nuclear Information System (INIS)

    The author underlines the insurers' reactions after the Chernobyl accident. Firstly, their reactions as providers of security for loss and destruction in power plants and for third party liability: offers of financial cover have not been affected - quite the contrary - since 26 April 1986. He then refers to their consideration of the detrimental consequences: Chernobyl has revealed a new aspect of nuclear incidents - the addition of various types of expenditure quite apart from compensation of personal injury or property may considerably increase their economic impact (NEA)

  18. Bioanalytical method transfer considerations of chromatographic-based assays.

    Science.gov (United States)

    Williard, Clark V

    2016-07-01

    Bioanalysis is an important part of the modern drug development process. The business practice of outsourcing and transferring bioanalytical methods from laboratory to laboratory has increasingly become a crucial strategy for successful and efficient delivery of therapies to the market. This chapter discusses important considerations when transferring various types of chromatographic-based assays in today's pharmaceutical research and development environment. PMID:27277876

  19. Ethical considerations in revision rhinoplasty.

    Science.gov (United States)

    Wayne, Ivan

    2012-08-01

    The problems that arise when reviewing another surgeon's work, the financial aspects of revision surgery, and the controversies that present in marketing and advertising will be explored. The technological advances of computer imaging and the Internet have introduced new problems that require our additional consideration. PMID:22872552

  20. Considerations on Writing Test Construction

    Institute of Scientific and Technical Information of China (English)

    王欣

    2005-01-01

    Writing test , wins its popularity in measuring the mastery of one's language ability. In view of the significant role writing playing in a test , some considerations on writing test construction are presented in this paper which anticipates the effective ways for measuring one's complex language ability of application.

  1. CSEWG SYMPOSIUM, A CSWEG RETROSPECTIVE. 35TH ANNIVERSARY CROSS SECTION EVALUATION WORKING GROUP, NOV. 5, 2001, BROOKHAVEN NATIONAL LABORATORY.

    Energy Technology Data Exchange (ETDEWEB)

    DUNFORD, C.; HOLDEN, N.; PEARLSTEIN, S.

    2001-11-05

    This publication has been prepared to record some of the history of the Cross Section Evaluation Working Group (CSEWG). CSEWG is responsible for creating the evaluated nuclear data file (ENDF/B) which is widely used by scientists and engineers who are involved in the development and maintenance of applied nuclear technologies. This organization has become the model for the development of nuclear data libraries throughout the world. The data format (ENDF) has been adopted as the international standard. On November 5, 2001, a symposium was held at Brookhaven National Laboratory to celebrate the 50 th meeting of the CSEWG organization and the 35 th anniversary of its first meeting in November 1966. The papers presented in this volume were prepared by present and former CSEWG members for presentation at the November 2001 symposium. All but two of the presentations are included. I have included an appendix to list all of the CSEWG members and their affiliations, which has been compiled from the minutes of each of the CSEWG meetings. Minutes exist for all meetings except the 4 th meeting held in January 1968. The list includes 348 individuals from 71 organizations. The dates for each of the 50 CSEWG meetings are listed. The committee structure and chairmen of all committees and subcommittees are also included in the appendix. This volume is dedicated to three individuals whose foresight and talents made CSEWG possible and successful. They are Henry Honeck who lead the effort to develop the ENDF format and the CSEWG system, Ira Zartman, the Atomic Energy Commission program manager who provided the programmatic direction and support, and Sol Pearlstein who led the development of the CESWG organization and the ENDF/B evaluated nuclear data library.

  2. Proposed ultraviolet free-electron laser at Brookhaven National Laboratory: A source for time-resolved biochemical spectroscopy

    International Nuclear Information System (INIS)

    Brookhaven National Laboratory is designing an ultraviolet free- electron laser (UV-FEL) user facility that will provide pico-second and sub-picosecond pulses of coherent ultraviolet radiation for wavelengths from 300 to 75 nm. Pulse width will be variable from abut 7 ps to ∼ 200 fs, with repetition rates as high as 104 Hz, single pulse energies > 1 mJ and hence peak pulse power >200 MW and average beam power > 10 W. The facility will be capable of ''pump-probe'' experiments utilizing the FEL radiation with: (1) synchronized auxiliary lasers, (2) a second, independently tunable FEL beam, or (3) broad-spectrum, high-intensity x-rays from the adjacent National Synchrotron Light Source. The UV-FEL consists of a high repetition rate recirculating superconducting linear accelerator which feeds pulses of electrons to two magnetic wigglers. Within these two devices, photons from tunable ''conventional'' laser would be frequency multiplied and amplified. By synchronously tuning the seed laser and modulating the energy of the electron beam, tuning of as much as 60% in wavelength is possible between alternating pulses supplied to different experimental stations, with Fourier transform limited resolution. Thus, up to four independent experiments may operate at one time, each with independent control of the wavelength and pulse duration. The UV-FEL will make possible new avenues of inquiry in time studies of diverse field including chemical, surface, and solid state physics, biology and materials science. The experimental area is scheduled to include a station dedicated to biological research. The complement of experimental and support facilities required by the biology station will be determined by the interests of the user community. 7 refs., 5 figs

  3. Tests of an environmental and personnel safe cleaning process for Brookhaven National Laboratory accelerator and storage ring components

    International Nuclear Information System (INIS)

    A large measure of the successful operation of the National Synchrotron Light Source (NSLS) at Brookhaven National Laboratory (BNL) for over a decade can be attributed to the cleaning of its ultrahigh vacuum (UHV) components during and after construction. A new UHV cleaning process, which has to be environmentally and personnel safe, is needed to replace the harsh, unfriendly process which is still in use. Dow Advanced Cleaning Systems was contracted to develop a replacement process without the use of harsh chemicals and which must clean vacuum surfaces as well as the existing process. Acceptance of the replacement process was primarily based on photon stimulated desorption (PSD) measurements of beam tube samples run on NSLS beam line U10B. One meter long beam tube samples were fabricated from aluminum, 304 stainless steel, and oxygen-free copper. Initially, coupon samples were cleaned and passed preliminary testing for the proposed process. Next, beam tube samples of each material were cleaned, and the PSD measured on beam line U10B using white light with a critical energy of 487 eV. Prior to cleaning, the samples were contaminated with a mixture of cutting oils, lubricants, vacuum oils, and vacuum grease. The contaminated samples were then baked. Samples of each material were also cleaned with the existing process after the same preparation. Beam tube samples were exposed to between 1022 and 1023 photons per meter for a PSD measurement. Desorption yields for H2, CO, CO2, CH4, and H2O are reported for both the existing cleaning and for the replacement cleaning process. Preliminary data, residual gas scans, and PSD results are given and discussed. The new process is also compared with new cleaning methods developed in other laboratories. After modification, the new UHV cleaning process was accepted by BNL

  4. Psychosocial considerations about children and radiological events

    International Nuclear Information System (INIS)

    Children are identified as a vulnerable population in the case of radiological events because of their increased physical sensitivity to radiation and its impact on critical development stages. Using a comprehensive integrated risk framework, psychosocial risk protective factors are discussed in a social ecology paradigm. Children have been shown to be both vulnerable and resilient; they are both easily impressionable and also quick to adapt and learn. Psychosocial interventions during, after and most efficiently before an event can improve outcome, especially if they involve parents and schools, media and work organisations. Public education through children should be encouraged to increase knowledge of radiation and strategies to minimise exposure and irradiation. Children can become vectors of prevention, preparedness and mitigation through information and behavioural rehearsal. Special consideration must therefore be given to education, school programmes, practice rehearsal and media exposure. (authors)

  5. Psychosocial considerations about children and radiological events.

    Science.gov (United States)

    Lemyre, Louise; Corneil, Wayne; Johnson, Colleen; Boutette, Paul

    2010-11-01

    Children are identified as a vulnerable population in the case of radiological events because of their increased physical sensitivity to radiation and its impact on critical development stages. Using a comprehensive integrated risk framework, psychosocial risk protective factors are discussed in a social ecology paradigm. Children have been shown to be both vulnerable and resilient; they are both easily impressionable and also quick to adapt and learn. Psychosocial interventions during, after and most efficiently before an event can improve outcome, especially if they involve parents and schools, media and work organisations. Public education through children should be encouraged to increase knowledge of radiation and strategies to minimise exposure and irradiation. Children can become vectors of prevention, preparedness and mitigation through information and behavioural rehearsal. Special consideration must therefore be given to education, school programmes, practice rehearsal and media exposure. PMID:20798186

  6. Implicit equity considerations in radiation protection standards

    International Nuclear Information System (INIS)

    The maturity of the practice of protecting against radiation provides a vehicle for testing both the definition of implied preference and the usefulness of any quantitative results. The author reviews the 50-year background and the rationale for imposing radiation standards. He analyzes the procedure for making quantitative risk estimates and their use to determine implied risk preference for occupational, individual, and population exposure. Equity did not emerge as a consideration in the early days when the threshold concept dominated, but did become an issue when different standards were set for workers and members of the general public; i.e., for voluntary/involuntary exposure. Intergeneration inequities have only recently become a critical issue. They arise because radioactive wastes have no productive value, but the strategic weapons program has assured some degree of social continuity. 19 references, 7 tables

  7. Consideration Sets and Competitive Marketing

    OpenAIRE

    Eliaz, K.; Spiegler, R.

    2006-01-01

    We study a market model in which competing �firms use costly marketing devices to influence the set of alternatives which consumers perceive as relevant. Consumers in our model are boundedly rational in the sense that they have an imperfect perception of what is relevant to their decision problem. They apply well-defined preferences to a "consideration set", which is a function of the marketing devices employed by the firms. We examine the implications of this behavioral model in the co...

  8. General B factory design considerations

    International Nuclear Information System (INIS)

    We describe the general considerations that go into the design of an asymmetric B factory collider. Justification is given for the typical parameters of such a facility, and the physics and technology challenges that arise from these parameter choices are discussed. Cost and schedule issues for a B factory are discussed briefly. A summary of existing proposals is presented, noting their similarities and differences. (orig.)

  9. Self-Neglect: Ethical Considerations.

    Science.gov (United States)

    Day, Mary Rose; Leahy-Warren, Patricia; McCarthy, Geraldine

    2016-01-01

    Self-neglect is a significant international public health issue. Estimates suggest that there may be over one million cases per year in the United States. Aging populations will put more people at risk of self-neglect. This chapter presents background literature, self-neglect definitions and policy context, risk factors, and a brief overview of research on perspectives of self-neglect from both clients and community health and social care professionals. A case study is presented from the perspective of an individual and is used to explore ethical issues therein. A person-centered assessment within a multidisciplinary team approach is required for building a therapeutic relationship with clients. Capacity is a central issue in the management of responses to self-neglect. Ethical considerations of importance for community health and social care professionals include beneficence and nonmaleficence, autonomy and capacity, and respect for people's rights and dignity. A model of ethical justification is presented to explain dilemmas, challenges, and actions. Competence of professionals, multidisciplinary team working, informed consent, privacy, confidentiality, and best interest are also critical considerations. Effective decision making by an interdisciplinary team of professionals needs to be person-centered and give due consideration to the best interest of self-neglecting clients. The purpose of this chapter is to provide an in-depth discussion and examination of ethical issues and challenges relating to self-neglecting clients. PMID:26673378

  10. Energy-related perturbations of the northeast coastal zone: five years (1974-1979) of oceanographic research at Brookhaven National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Walsh, J.J.

    1980-03-01

    Since inception of oceanographic research at Brookhaven National Laboratory in 1974, over 75 cruises and 150 papers and reports have been completed. In comparison of shelf ecosystems at high, mid, and low latitudes, an understanding of the natural variability of US coastal waters has been derived. Annual carbon and nitrogen budgets suggest that the energy flow is diverted to a pelagic food web in summer-fall and a demersal food web in winter-spring within the Mid-Atlantic Bight. The impact of energy-related perturbations can now be assessed within the context of natural oscillation of the coastal food web.

  11. Features material considerations polyester resins

    OpenAIRE

    Алексеева, Н. Н.; Маслош, О. В.; Островерхова, И. А.; Маслош, В. З.

    2011-01-01

    The features of drafting of financial balance of processes of receipt of polyester resins are considered. It is marked that practical output of polyesters always anymore theoretical. The method of drafting of financial balance of processes of receipt of polyesters is offered.

  12. Ethical Considerations for Internet Counseling.

    Science.gov (United States)

    Attridge, William C.

    With the advent of new technologies, the possibility for providing quality, Internet-based, therapeutic counseling services becomes more attainable and realistic every year. Since the National Board for Certified Counselors announced the adoption of voluntary standards for the practice of Internet-based counseling, a new dimension has been added…

  13. Fitness for All: Conceptual Considerations.

    Science.gov (United States)

    Lockhart, Barbara D.

    1994-01-01

    Article proposes concepts that could be the basis for fitness attitudes and practices for all people regardless of skill, age, or expertise. An intrinsic definition of fitness highlights the importance of exercise and relaxation to fitness, integration of the whole self, and acceptance of self based on inherent worth. (SM)

  14. Self-Assembly by Instruction: Designing Nanoscale Systems Using DNA-Based Approaches (474th Brookhaven Lecture)

    Energy Technology Data Exchange (ETDEWEB)

    Gang, Oleg [Center for Functional Nanomaterials

    2012-01-18

    In the field of nanoscience, if you can control how nanoparticles self-assemble in particular structures — joining each other, for example, as molecules can form, atom-by-atom — you can design new materials that have unique properties that industry needs. Nature already uses the DNA genetic code to instruct the building of specific proteins and whole organisms in both plants and people. Taking a cue from nature, scientists at BNL devised a way of using strands of synthetic DNA attached to the surface of nanoparticles to instruct them to self-assemble into specific nanoscale structures, clusters, and three-dimensional organizations. Novel materials designed and fabricated this way promise use in photovoltaics, energy storage, catalysis, cell-targeted systems for more effective medical treatments, and biomolecular sensing for environmental monitoring and medical applications. To find out more about the rapid evolution of this nanoassembly method and its applications, join Physicist Oleg Gang of the Center for Functional Nanomaterials (CFN) as he gives the 474th Brookhaven Lecture, titled “Self-Assembly by Instruction: Designing Nanoscale Systems Using DNA-Based Approaches." Gang, who has led this work at the CFN, will explain the rapid evolution of this nanoassembly method, and discuss its present and future applications in highly specific biosensors, optically active nano-materials, and new ways to fabricate complex architectures in a rational manner via self-assembly. Gang and his colleagues used the CFN and the National Synchrotron Light Source (NSLS) facilities to perform their groundbreaking research. At the CFN, the scientists used electron microscopes and optical methods to visualize the clusters that they fabricated. At the NSLS, they applied x-rays to study a particles-assembly process in solution, DNA’s natural environment. Gang earned a Ph.D. in soft matter physics from Bar-Ilan University in 2000, and he was a Rothschild Fellow at Harvard

  15. Proceedings of RIKEN BNL Research Center Workshop: Brookhaven Summer Program on Quarkonium Production in Elementary and Heavy Ion Collisions

    Energy Technology Data Exchange (ETDEWEB)

    Dumitru, A.; Lourenco, C.; Petreczky, P.; Qiu, J., Ruan, L.

    2011-08-03

    Understanding the structure of the hadron is of fundamental importance in subatomic physics. Production of heavy quarkonia is arguably one of the most fascinating subjects in strong interaction physics. It offers unique perspectives into the formation of QCD bound states. Heavy quarkonia are among the most studied particles both theoretically and experimentally. They have been, and continue to be, the focus of measurements in all high energy colliders around the world. Because of their distinct multiple mass scales, heavy quarkonia were suggested as a probe of the hot quark-gluon matter produced in heavy-ion collisions; and their production has been one of the main subjects of the experimental heavy-ion programs at the SPS and RHIC. However, since the discovery of J/psi at Brookhaven National Laboratory and SLAC National Accelerator Laboratory over 36 years ago, theorists still have not been able to fully understand the production mechanism of heavy quarkonia, although major progresses have been made in recent years. With this in mind, a two-week program on quarkonium production was organized at BNL on June 6-17, 2011. Many new experimental data from LHC and from RHIC were presented during the program, including results from the LHC heavy ion run. To analyze and correctly interpret these measurements, and in order to quantify properties of the hot matter produced in heavy-ion collisions, it is necessary to improve our theoretical understanding of quarkonium production. Therefore, a wide range of theoretical aspects on the production mechanism in the vacuum as well as in cold nuclear and hot quark-gluon medium were discussed during the program from the controlled calculations in QCD and its effective theories such as NRQCD to various models, and to the first principle lattice calculation. The scientific program was divided into three major scientific parts: basic production mechanism for heavy quarkonium in vacuum or in high energy elementary collisions; the

  16. Application of the SmartSampling Methodology to the Evaluation of Contaminated Landscape Soils at Brookhaven National Laboratory

    International Nuclear Information System (INIS)

    Portions of the SmartSamplingtrademark analysis methodology have been applied to the evaluation of radioactive contaminated landscape soils at Brookhaven National Laboratory. Specifically, the spatial, volumetric distribution of cesium-137 (137Cs) contamination within Area of Concern 16E-1 has been modeled probabilistically using a geostatistical methodology, with the purpose of identifying the likelihood of successfully reducing, with respect to a pre-existing, baseline remediation plan, the volume of soil that must be disposed of offsite during clean-up. The principal objective of the analysis was to evaluate the likelihood of successful deployment of the Segmented Gate System (SGS), a novel remediation approach that emphasizes real-time separation of clean from contaminated materials during remediation operations. One primary requirement for successful application of the segmented gate technology investigated is that a variety of contaminant levels exist at the deployment site, which would enable to the SGS to discriminate material above and below a specified remediation threshold value. The results of this analysis indicate that there is potential for significant volume reduction with respect to the baseline remediation plan at a threshold excavation level of 23 pCi/g 137Cs. A reduction of approximately 50%, from a baseline volume of approximately 1,064.7 yd3 to less than 550 yd3, is possible with acceptance of only a very small level of engineering risk. The vast majority of this volume reduction is obtained by not excavating almost all of levels 3 and 4 (from 12 to 24 inches in depth), which appear to be virtually uncontaminated, based on the available data. Additional volume reductions related to soil materials on levels 1 (depths of 0--6 inches) and 2 (6--12 inches) may be possible, specifically through use of the SGS technology. Level-by-level evaluation of simulation results suggests that as much as 26 percent of level 1 and as much as 65% of level 2

  17. Commercial considerations in tissue engineering.

    Science.gov (United States)

    Mansbridge, Jonathan

    2006-10-01

    Tissue engineering is a field with immense promise. Using the example of an early tissue-engineered skin implant, Dermagraft, factors involved in the successful commercial development of devices of this type are explored. Tissue engineering has to strike a balance between tissue culture, which is a resource-intensive activity, and business considerations that are concerned with minimizing cost and maximizing customer convenience. Bioreactor design takes place in a highly regulated environment, so factors to be incorporated into the concept include not only tissue culture considerations but also matters related to asepsis, scaleup, automation and ease of use by the final customer. Dermagraft is an allogeneic tissue. Stasis preservation, in this case cryopreservation, is essential in allogeneic tissue engineering, allowing sterility testing, inventory control and, in the case of Dermagraft, a cellular stress that may be important for hormesis following implantation. Although the use of allogeneic cells provides advantages in manufacturing under suitable conditions, it raises the spectre of immunological rejection. Such rejection has not been experienced with Dermagraft. Possible reasons for this and the vision of further application of allogeneic tissues are important considerations in future tissue-engineered cellular devices. This review illustrates approaches that indicate some of the criteria that may provide a basis for further developments. Marketing is a further requirement for success, which entails understanding of the mechanism of action of the procedure, and is illustrated for Dermagraft. The success of a tissue-engineered product is dependent on many interacting operations, some discussed here, each of which must be performed simultaneously and well. PMID:17005024

  18. Circuit considerations for repetitive railguns

    Energy Technology Data Exchange (ETDEWEB)

    Honih, E.M.

    1986-01-01

    Railgun electromagnetic launchers have significant military and scientific potential. They provide direct conversion of electrical energy to projectile kinetic energy, and they offer the hope of achieving projectile velocities greatly exceeding the limits of conventional guns. With over 10 km/sec already demonstrated, railguns are attracting attention for tactical and strategic weapons systems and for scientific equation-of-state research. The full utilization of railguns will require significant improvements in every aspect of system design - projectile, barrel, and power source - to achieve operation on a large scale. This paper will review fundamental aspects of railguns, with emphasis on circuit considerations and repetitive operation.

  19. Brookhaven: Spin result underlined

    International Nuclear Information System (INIS)

    A recent experiment looking at violent proton-proton elastic scattering confirms, with high precision, earlier data which puzzled many theorists. Most pictures of strong interactions based on perturbative quark-gluon field theory (Quantum Chromodynamics, QCD) suggested that spin effects should disappear with energy and as the collisions become more violent

  20. Brookhaven highlights 1994

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-12-31

    Established in 1947 on Long Island, New York, on the site of the former army Camp Upton, BNL is a multidisciplinary laboratory that carries out basic and applied research in the physical, biomedical and environmental sciences and in selected energy technologies. The Laboratory is managed by Associated Universities, Inc., under contract to the US Department of Energy. BNL`s annual budget is about $400 million, and the Laboratory`s facilities are valued at replacements cost in excess of over $2.8 billion. Employees number around 3,300,and over 4,000 guests, collaborators and students come each year to use the Laboratory`s facilities and work with the staff. Scientific and technical achievements at BNL have made their way into daily life in areas as varied as health care, construction materials and video games. The backbone of these developments is fundamental research, which is and always will be an investment in the future.

  1. Brookhaven National Laboratory

    Science.gov (United States)

    ... big data challenges facing researchers in science, technology, engineering, and mathematics ... fundamental research in nuclear and particle physics to gain a deeper understanding of matter, energy, ...

  2. Brookhaven highlights 1994

    International Nuclear Information System (INIS)

    Established in 1947 on Long Island, New York, on the site of the former army Camp Upton, BNL is a multidisciplinary laboratory that carries out basic and applied research in the physical, biomedical and environmental sciences and in selected energy technologies. The Laboratory is managed by Associated Universities, Inc., under contract to the US Department of Energy. BNL's annual budget is about $400 million, and the Laboratory's facilities are valued at replacements cost in excess of over $2.8 billion. Employees number around 3,300,and over 4,000 guests, collaborators and students come each year to use the Laboratory's facilities and work with the staff. Scientific and technical achievements at BNL have made their way into daily life in areas as varied as health care, construction materials and video games. The backbone of these developments is fundamental research, which is and always will be an investment in the future

  3. Three essays on resource economics. Demand systems for energy forecasting: Practical considerations for estimating a generalized logit model, To borrow or not to borrow: A variation on the MacDougal-Kemp theme, and, Valuing reduced risk for households with children or the retired

    Science.gov (United States)

    Weng, Weifeng

    This thesis presents papers on three areas of study within resource and environmental economics. "Demand Systems For Energy Forecasting" provides some practical considerations for estimating a Generalized Logit model. The main reason for using this demand system for energy and other factors is that the derived price elasticities are robust when expenditure shares are small. The primary objective of the paper is to determine the best form of the cross-price weights, and a simple inverse function of the expenditure share is selected. A second objective is to demonstrate that the estimated elasticities are sensitive to the units specified for the prices, and to show how price scales can be estimated as part of the model. "To Borrow or Not to Borrow: A Variation on the MacDougal-Kemp Theme" studies the impact of international capital movements on the conditional convergence of economies differing from each other only in initial wealth. We found that in assets, income, consumption and utility, convergence obtains, with and only with, the absence of international capital movement. When a rich country invests in a poor country, the balance of debt increases forever. Asset ownership is increased in all periods for the lender, and asset ownership of the borrower is deceased. Also, capital investment decreases the lender's utility for early periods, but increases it forever after a cross-over point. In contrast, the borrower's utility increases for early periods, but then decreases forever. "Valuing Reduced Risk for Households with Children or the Retired" presents a theoretical model of how families value risk and then exams family automobile purchases to impute the average Value of a Statistical Life (VSL) for each type of family. Data for fatal accidents are used to estimate survival rates for individuals in different types of accidents, and the probabilities of having accidents for different types of vehicle. These models are used to determine standardized risks for

  4. Mechanical considerations and design skills.

    Energy Technology Data Exchange (ETDEWEB)

    Alvis, Robert L.

    2008-03-01

    The purpose of the report is to provide experienced-based insights into design processes that will benefit designers beginning their employment at Sandia National Laboratories or those assuming new design responsibilities. The main purpose of this document is to provide engineers with the practical aspects of system design. The material discussed here may not be new to some readers, but some of it was to me. Transforming an idea to a design to solve a problem is a skill, and skills are similar to history lessons. We gain these skills from experience, and many of us have not been fortunate enough to grow in an environment that provided the skills that we now need. I was fortunate to grow up on a farm where we had to learn how to maintain and operate several different kinds of engines and machines. If you are like me, my formal experience is partially based upon the two universities from which I graduated, where few practical applications of the technologies were taught. What was taught was mainly theoretical, and few instructors had practical experience to offer the students. I understand this, as students have their hands full just to learn the theoretical. The practical part was mainly left up to 'on the job experience'. However, I believe it is better to learn the practical applications early and apply them quickly 'on the job'. System design engineers need to know several technical things, both in and out of their field of expertise. An engineer is not expected to know everything, but he should know when to ask an expert for assistance. This 'expert' can be in any field, whether it is in analyses, drafting, machining, material properties, testing, etc. The best expert is a person who has practical experience in the area of needed information, and consulting with that individual can be the best and quickest way for one to learn. If the information provided here can improve your design skills and save one design from having a problem

  5. Nutritional Considerations for Cancer Patients

    OpenAIRE

    Chen, Angela

    1985-01-01

    Although weight loss is a frequent, though not invariable, component of the cancer syndrome, the associated malnutrition is a poor prognostic sign among both children and adults. This article describes the possible mechanisms of cancer cachexia; reviews the present state of nutritional support in cancer patients; identifies nutritional problems and workable approaches during the pre- and post-treatment periods; discusses the unconventional nutritional practices commonly encountered and lists ...

  6. Considerations concerning cosumer behaviour theory

    OpenAIRE

    Ioan Cucu; Codruta Dura

    2001-01-01

    The consumer`s scale of preference, which is the starting point of the theory of consumer behaviour can be ilustrated very clearly by indifference curves. The point where budget line meets the highest possible indifference curve compatible with the consumer`s income and prices represents the state of equilibrum for the consumer. Consumer behaviuor theory gains still more practical importance if consumer preferences are subjected to detailed psychological and sociological analysis.

  7. [Occult child abuse (opinions, considerations, personal observations)].

    Science.gov (United States)

    Paci, A; Migliaccio, P; Paci, G

    1999-01-01

    At the beginning of the statement the authors point out some lesser aspects of child's ill-treatment (previously suggested by them in other occasions) as expressions of very strict educational systems which strongly limit childrens' freedom or impose them several extrascholastic activities (such as: athletics, music with participation in competitive examination, studies of foreign languages, Latin and so on) where the child must excel in (composex of the "leader-child"). Then these authors suggest using the term "abuse" to mean lexically every excessive, undue, arbitrary use and not only "sexual". They point out the seriousness of abuse as far as juvenile exploitation is concerned both in case of manual labour and prostitution. But the pay particularly attention to the problem of sport when it is gone in for too intensively (as athletics). These authors infact sum up the harms that sport can cause when it is gone in for during the age under the stabilized puberty. Physical harms may occur especially during the practice of risky sports such as: Alpine skiing, cycling on the road, swimming combined with diving, fencing, boxing) and during tiring condition, while psychic harms can entail a fall in scholastic performances, irritability, insomnia, anxiety. The authors depreciate the behaviour of those parents who stimulate their children' aggressiveness during competitions and scold them when their performances are insufficient, or give them forbidden stimulants of hormonal anabolic drugs instead of taking care of their children in order to keep away from the arms mentioned above. However, after all these observations and considerations about competitive sports in juvenile age, these authors can firmly state that all this could be meant as an important aspects of the juvenile exploitation that must be taken in great consideration. PMID:11293144

  8. Assessment: Examining Practice in Entrepreneurship Education

    Science.gov (United States)

    Pittaway, Luke; Edwards, Corina

    2012-01-01

    Purpose: The purpose of this paper is to develop knowledge about the nature of student assessment practice in entrepreneurship education. Design/methodology/approach: This paper introduces general assessment practice issues and highlights key considerations. It explains prior research on assessment practice in entrepreneurship education and argues…

  9. Security Consideration With Dynamic Routing

    Directory of Open Access Journals (Sweden)

    VISWESWARARAO BOLLA

    2012-03-01

    Full Text Available One of the major issues for data communication over wired and wireless networks is the security. the past work is on the designs of cryptography algorithms and system infrastructures. Dynamic routing algorithm called improved dynamic routing with security consideration, which is based on the concept of Zone Routing Protocol (ZRP that could randomize delivery paths for data transmission. The algorithm is easy to implement and compatible with popular routing protocols, such as the Routing Information Protocol (RIP in wired networks and Destination-Sequenced Distance Vector (DSDV protocol in wireless networks, without introducing extra control messages. This algorithm is mainly proposed to improve the and to overcome the limitations existing with the present cryptographic algorithms and protocols. Although some designs like IP security, Secure Socket Layer provide essential security, E-Mail security they unavoidably introduce substantial overheads in the Gateway/Host performance and effective network bandwidths.

  10. Multi-unit operations considerations

    International Nuclear Information System (INIS)

    Several nuclear weapons programs have or are pursuing the implementation of multi-unit operations for tasks such as disassembly and inspection, and rebuild. A multi-unit operation is interpreted to mean the execution of nuclear explosive operating procedures in a single facility by two separate teams of technicians. The institution of a multi-unit operations program requires careful consideration of the tools, resources, and environment provided to the technicians carrying out the work. Therefore, a systematic approach is necessary to produce safe, secure, and reliable processes. In order to facilitate development of a more comprehensive multi-unit operations program, the current work details categorized issues that should be addressed prior to the implementation of multi-unit operations in a given weapons program. The issues have been organized into the following categories: local organizational conditions, work process flow/material handling/workplace configuration, ambient environmental conditions, documented safety analysis, and training

  11. Sodium concrete reaction: structural considerations

    International Nuclear Information System (INIS)

    An overview of the sodium concrete reaction phenomenon, with emphasis on structural considerations, is presented. Available test results for limestone, basalt, and magnetite concrete with various test article configurations are reviewed. Generally, tests indicate reaction is self limiting before all sodium is used. Uncertainties, however, concerning the mechanism for penetration of sodium into concrete have resulted in different theories about a reaction model. Structural behavior may be significant in the progression of the reaction due to thermal-structural-chemical interactions involving tensile cracking, compressive crushing, or general deterioration of concrete and the exposure of fresh concrete surfaces to react with sodium. Structural behavior of test articles and potential factors that could enhance the progression of the reaction are discussed

  12. Environmental considerations in PHWR systems

    International Nuclear Information System (INIS)

    Siting of Nuclear Power Plants (NPPs) involves consideration of environmental factors and design characteristics of the reactor in combination. The environmental aspects can be broadly classified into two categories, namely, (1) those that affect the safety of the power plant and (2) those that have an impact on the public and environment. Factors such as seismicity, subsidence, liquefaction, flooding, air-craft crashes and proximity to toxic/explosive chemicals are some of the aspects which have a bearing on the safe operation of the plant. On the other hand, population distribution in the immediate environs of the site, meteorology, surface hydrology, geohydrology and dietary and dwelling habits of the people in the surrounding areas are the site characteristics which contribute to the environmental impact. All these aspects have been briefly discussed in this paper consistent with IAEA-NUSS programme. (author). 6 refs

  13. Consideration of convergence judgment method with source acceleration in Monte Carlo criticality calculation

    International Nuclear Information System (INIS)

    Theoretical consideration is made for possibility to accelerate and judge convergence of a conventional Monte Carlo iterative calculation when it is used for a weak neutron interaction problem. And the clue for this consideration is rendered with some application analyses using the OECD/NEA source convergence benchmark problems. Some practical procedures are proposed to realize these acceleration and judgment methods in practical application using a Monte Carlo code. (author)

  14. Special Consideration in Post-Secondary Institutions: Trends at a Canadian University

    Science.gov (United States)

    Zimmermann, Joelle; Kamenetsky, Stuart B.; Pongracic, Syb

    2015-01-01

    This study examined trends in the practice of granting special consideration for missed tests and late papers in colleges and universities. We analyzed a database of 4,183 special consideration requests at a large Canadian university between 1998 and 2008. Results show a growing rate of requests per enrolment between 2001 and 2007. Although…

  15. Supplemental oxygen therapy: Important considerations in oral and maxillofacial surgery

    OpenAIRE

    Singh, Virendra; Gupta, Pranav; Khatana, Shruti; Bhagol, Amrish

    2011-01-01

    The administration of supplemental oxygen is an essential element of appropriate management for a wide range of clinical conditions; crossing different medical and surgical specialities. The present review summarizes the role of supportive oxygen therapy in various clinical conditions encountered in our day-to-day practice in the speciality of oral and maxillofacial surgery; including major trauma, shock, sepsis; perioperative and postoperative considerations and in patients with various othe...

  16. Considerations in using radiation dosimetry data in epidemiologic studies

    International Nuclear Information System (INIS)

    From experience to date, it is concluded that cohorts can be divided into useable risk groups without need for extensive calculations of individual doses. Several possible risk group classification schemes are presented for use with standard methods of data analysis. The rationale, advantages, and disadvantages of each are discussed with respect to possible classification biases, and statistical and practical considerations. Data from a cohort of nuclear material workers are used to illustrate these dichotomous and ordinal schemes

  17. Slowing tropical forest biodiversity losses: Cost and compensation considerations

    OpenAIRE

    Kramer, R

    1996-01-01

    This paper discusses some of the work that has been done on cost estimation of biodiversity conservation for protected areas in the tropics. It also summarizes some conceptual and practical considerations related to compensating local residents who lose land use opportunities due to conservation activities. The main costs associated with conservation and the creation of national parks or reserves arise from land acquisition, hiring and training personnel, and the development of infrastructure...

  18. A Study of Higher-Order Mode Damping in the Superconducting Energy Recovery LINAC at Brookhaven National Laboratory

    Science.gov (United States)

    Hammons, Lee Reginald, III

    An energy recovery LINAC (ERL) is being constructed at Brookhaven National Laboratory that will involve a superconducting LINAC along with a superconducting electron gun, all operating at 703.75 MHz. The ERL will serve as a testbed for the concepts and technologies required to implement future upgrades in the Relativistic Heavy Ion Collider (RHIC). Because of the high current and high charge requirements of the ERL, effective higher-order mode (HOM) damping is an essential component of the ERL research and development program. This thesis focuses on three areas of HOM characterization and damping development: damping of HOMs in the five-cell LINAC, use of the electron gun fundamental power couplers (FPCs) to damp HOMs, and the development of a ceramic/ferrite damper for the electron gun. The five-cell LINAC uses an HOM load lined with ferrite and attached to the beampipe on either side of the cavity. These studies characterized the frequency-dependent nature of the ferrite absorbing material and derived a set of "portable" ferrite parameters that simplified simulation work. Using these "portable" parameters, it was determined that the ferrite absorber is effective in damping the HOMs of the five-cell cavity over a range of frequencies. In addition, higher-order mode damping in the electron gun was studied using the fundamental power couplers. The gun cavity is a superconducting half-cell structure designed to accelerate electrons to an energy of 2.5 MeV and features dual fundamental power couplers. The HOMs of the gun cavity were studied along with the damping capabilities of the FPCs. Simulation studies determined that the FPCs couple strongly to many of the HOMs studied. However, the transition between the coaxial FPCs and the waveguide that feeds power to the FPCs is a "doorknob" type transition, and it was found that this component shows the best transmission qualities between 1 and 2 GHz, thus limiting the damping capabilities of the FPCs to this bandwidth. It

  19. Space Tourism: Orbital Debris Considerations

    Science.gov (United States)

    Mahmoudian, N.; Shajiee, S.; Moghani, T.; Bahrami, M.

    2002-01-01

    Space activities after a phase of research and development, political competition and national prestige have entered an era of real commercialization. Remote sensing, earth observation, and communication are among the areas in which this growing industry is facing competition and declining government money. A project like International Space Station, which draws from public money, has not only opened a window of real multinational cooperation, but also changed space travel from a mere fantasy into a real world activity. Besides research activities for sending man to moon and Mars and other outer planets, space travel has attracted a considerable attention in recent years in the form of space tourism. Four countries from space fairing nations are actively involved in the development of space tourism. Even, nations which are either in early stages of space technology development or just beginning their space activities, have high ambitions in this area. This is worth noting considering their limited resources. At present, trips to space are available, but limited and expensive. To move beyond this point to generally available trips to orbit and week long stays in LEO, in orbital hotels, some of the required basic transportations, living requirements, and technological developments required for long stay in orbit are already underway. For tourism to develop to a real everyday business, not only the price has to come down to meaningful levels, but also safety considerations should be fully developed to attract travelers' trust. A serious hazard to space activities in general and space tourism in particular is space debris in earth orbit. Orbiting debris are man-made objects left over by space operations, hazardous to space missions. Since the higher density of debris population occurs in low earth orbit, which is also the same orbit of interest to space tourism, a careful attention should be paid to the effect of debris on tourism activities. In this study, after a

  20. ALARP considerations in criticality safety assessments

    International Nuclear Information System (INIS)

    Demonstrating that the risk to the public and workers is As Low As Reasonably Practicable (ALARP) is a fundamental requirement of safety cases for nuclear facilities in the United Kingdom. This is embodied in the Safety Assessment Principles (SAPs) published by the Regulator, the essence of which is incorporated within the safety assessment processes of the various nuclear site licensees. The concept of ALARP within criticality safety assessments has taken some time to establish in the United Kingdom. In principle, the licensee is obliged to search for a deterministic criticality safety solution, such as safe geometry vessels and passive control features, rather than placing reliance on active measurement devices and plant administrative controls. This paper presents a consideration of some ALARP issues in relation to the development of criticality safety cases. The paper utilises some idealised examples covering a range of issues facing the criticality safety assessor, including new plant design, operational plant and decommissioning activities. These examples are used to outline the elements of the criticality safety cases and present a discussion of ALARP in the context of criticality safety assessments. (author)