WorldWideScience

Sample records for broad-band ft-icr penning

  1. A broad-Band FT-ICR Penning TRap System for KATRIN

    CERN Document Server

    Ubieto-Diaz, M; Lukic, S; Nagy, Sz; Stahl, S; Blaum, K

    2009-01-01

    The KArlsruhe TRItium Neutrino experiment KATRIN aims at improving the upper limit of the mass of the electron antineutrino to about 0.2 eV (90% c.l.) by investigating the beta-decay of tritium gas molecules. The experiment is currently under construction to start first data taking in 2012. One source of systematic uncertainties in the KATRIN experiment is the formation of ion clusters when tritium decays and decay products interact with residual tritium molecules. It is essential to monitor the abundances of these clusters since they have different final state energies than tritium ions. For this purpose, a prototype of a cylindrical Penning trap has been constructed and tested at the Max-Planck-Institute for Nuclear Physics in Heidelberg, which will be installed in the KATRIN beam line. This system employs the technique of Fourier-Transform Ion-Cyclotron-Resonance in order to measure the abundances of the different stored ion species.

  2. Simultaneous monitoring of the radial modes of the ion motion and their manipulation in Penning traps by FT-ICR mass spectrometry

    CERN Document Server

    Breitenfeldt, M; Herlert, A; Marxa, G; Schweikhard, L

    2007-01-01

    It is demonstrated how FT-ICR MS can be used to monitor both the coherent magnetron motion and the cyclotron motion of ions stored in a Penning trap. By use of the ICR signal intensity at the magnetron frequency, ν−, and the reduced cyclotron frequency, ν+, the manipulation of the ion motion by dipolar, quadrupolar, and octupolar excitation has been followed. In particular, the conversion between the magnetron and the cyclotron motion by quadrupolar and octupolar excitation at the corresponding resonance frequencies νc = ν+ + ν− and 2νc, respectively, has been observed by detection of the magnetron and the cyclotron signal. While the ion motion under the influence of a quadrupolar excitation has already been studied extensively, the octupolar excitation has been introduced only recently. As compared to other techniques, such as the time-of-flight ion-cyclotron-resonance detection method, FT-ICR MS allows to simultaneously investigate the influence of an excitation on the cyclotron und the magnetron ...

  3. Structural Characterization of Anhydroicaritin Glycosides Using ESI-FT-ICR Mass Spectrometry

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR-MS) was used to determine the structures of anhydroicaritin glycosides by the MS/MS experiments of anhydroicaritin glycosides and their methylated derivatives. With high accuracy FT-ICR-MS provides much information about the structures of compounds, FT-ICR-MS shows the great potential application in the structural characterization of unknown compounds.

  4. Tracking the Magnetron Motion in FT-ICR Mass Spectrometry

    Science.gov (United States)

    Jertz, Roland; Friedrich, Jochen; Kriete, Claudia; Nikolaev, Evgeny N.; Baykut, Gökhan

    2015-08-01

    In Fourier transform ion cyclotron resonance spectrometry (FT-ICR MS) the ion magnetron motion is not usually directly measured, yet its contribution to the performance of the FT-ICR cell is important. Its presence is manifested primarily by the appearance of even-numbered harmonics in the spectra. In this work, the relationship between the ion magnetron motion in the ICR cell and the intensities of the second harmonic signal and its sideband peak in the FT-ICR spectrum is studied. Ion motion simulations show that during a cyclotron motion excitation of ions which are offset to the cell axis, a position-dependent radial drift of the cyclotron center takes place. This radial drift can be directed outwards if the ion is initially offset towards one of the detection electrodes, or it can be directed inwards if the ion is initially offset towards one of the excitation electrodes. Consequently, a magnetron orbit diameter can increase or decrease during a resonant cyclotron excitation. A method has been developed to study this behavior of the magnetron motion by acquiring a series of FT-ICR spectra using varied post-capture delay (PCD) time intervals. PCD is the delay time after the capture of the ions in the cell before the cyclotron excitation of the ion is started. Plotting the relative intensity of the second harmonic sideband peak versus the PCD in each mass spectrum leads to an oscillating "PCD curve". The position and height of minima and maxima of this curve can be used to interpret the size and the position of the magnetron orbit. Ion motion simulations show that an off-axis magnetron orbit generates even-numbered harmonic peaks with sidebands at a distance of one magnetron frequency and multiples of it. This magnetron offset is due to a radial offset of the electric field axis versus the geometric cell axis. In this work, we also show how this offset of the radial electric field center can be corrected by applying appropriate DC correction voltages to the

  5. Fourier transform ion cyclotron resonance (FT ICR) mass spectrometry: Theory and simulations.

    Science.gov (United States)

    Nikolaev, Eugene N; Kostyukevich, Yury I; Vladimirov, Gleb N

    2016-01-01

    Fourier transform ion cyclotron resonance (FT ICR) mass spectrometer offers highest resolving power and mass accuracy among all types of mass spectrometers. Its unique analytical characteristics made FT ICR important tool for proteomics, metabolomics, petroleomics, and investigation of complex mixtures. Signal acquisition in FT ICR MS takes long time (up to minutes). During this time ion-ion interaction considerably affects ion motion and result in decreasing of the resolving power. Understanding of those effects required complicated theory and supercomputer simulations but culminated in the invention of the ion trap with dynamic harmonization which demonstrated the highest resolving power ever achieved. In this review we summarize latest achievements in theory and simulation of FT ICR mass spectrometers.

  6. Developments in FT-ICR MS instrumentation, ionization techniques, and data interpretation methods for petroleomics.

    Science.gov (United States)

    Cho, Yunju; Ahmed, Arif; Islam, Annana; Kim, Sunghwan

    2015-01-01

    Because of the increasing importance of heavy and unconventional crude oil as an energy source, there is a growing need for petroleomics: the pursuit of more complete and detailed knowledge of the chemical compositions of crude oil. Crude oil has an extremely complex nature; hence, techniques with ultra-high resolving capabilities, such as Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS), are necessary. FT-ICR MS has been successfully applied to the study of heavy and unconventional crude oils such as bitumen and shale oil. However, the analysis of crude oil with FT-ICR MS is not trivial, and it has pushed analysis to the limits of instrumental and methodological capabilities. For example, high-resolution mass spectra of crude oils may contain over 100,000 peaks that require interpretation. To visualize large data sets more effectively, data processing methods such as Kendrick mass defect analysis and statistical analyses have been developed. The successful application of FT-ICR MS to the study of crude oil has been critically dependent on key developments in FT-ICR MS instrumentation and data processing methods. This review offers an introduction to the basic principles, FT-ICR MS instrumentation development, ionization techniques, and data interpretation methods for petroleomics and is intended for readers having no prior experience in this field of study.

  7. Vacuum Ultraviolet Photodissociation and Fourier Transform–Ion Cyclotron Resonance (FT-ICR) Mass Spectrometry: Revisited

    Energy Technology Data Exchange (ETDEWEB)

    Shaw, Jared B.; Robinson, Errol W.; Pasa-Tolic, Ljiljana

    2016-02-16

    We revisited the implementation of UVPD within the ICR cell of a FT-ICR mass spectrometer. UVPD performance characteristics were examined in the context of recent developments in the understanding of UVPD and in-cell tandem mass spectrometry. Efficient UVPD and photo-ECD of a model peptide and small protein within the ICR cell of a FT-ICR mass spectrometer are accomplished through appropriate modulation of laser pulse timing relative to ion magnetron motion and the potential applied to an ion optical element that photons impinge on. It is shown that UVPD yields efficient and extensive fragmentation resulting in excellent sequence coverage for model peptide and protein cations.

  8. Extracting biomolecule collision cross sections from the high-resolution FT-ICR mass spectral linewidths.

    Science.gov (United States)

    Jiang, Ting; Chen, Yu; Mao, Lu; Marshall, Alan G; Xu, Wei

    2016-01-14

    It is known that the ion collision cross section (CCS) may be calculated from the linewidth of a Fourier transform ion cyclotron resonance (FT-ICR) mass spectral peak at elevated pressure (e.g., ∼10(-6) Torr). However, the high mass resolution of FT-ICR is sacrificed in those experiments due to high buffer gas pressure. In this study, we describe a linewidth correction method to eliminate the windowing-induced peak broadening effect. Together with the energetic ion-neutral collision model previously developed by our group, this method enables the extraction of CCSs of biomolecules from high-resolution FT-ICR mass spectral linewidths, obtained at a typical operating buffer gas pressure of modern FT-ICR instruments (∼10(-10) Torr). CCS values of peptides including MRFA, angiotensin I, and bradykinin measured by the proposed method agree well with ion mobility measurements, and the unfolding of protein ions (ubiquitin) at higher charge states is also observed. PMID:26314765

  9. Application of Printed Circuit Board Technology to FT-ICR MS Analyzer Cell Construction and Prototyping

    Science.gov (United States)

    Leach, Franklin E.; Norheim, Randolph; Anderson, Gordon; Pasa-Tolic, Ljiljana

    2014-12-01

    Although Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS) remains the mass spectrometry platform that provides the highest levels of performance for mass accuracy and resolving power, there is room for improvement in analyzer cell design as the ideal quadrupolar trapping potential has yet to be generated for a broadband MS experiment. To this end, analyzer cell designs have improved since the field's inception, yet few research groups participate in this area because of the high cost of instrumentation efforts. As a step towards reducing this barrier to participation and allowing for more designs to be physically tested, we introduce a method of FT-ICR analyzer cell prototyping utilizing printed circuit boards at modest vacuum conditions. This method allows for inexpensive devices to be readily fabricated and tested over short intervals and should open the field to laboratories lacking or unable to access high performance machine shop facilities because of the required financial investment.

  10. Vacuum Ultraviolet Photodissociation and Fourier Transform-Ion Cyclotron Resonance (FT-ICR) Mass Spectrometry: Revisited.

    Science.gov (United States)

    Shaw, Jared B; Robinson, Errol W; Paša-Tolić, Ljiljana

    2016-03-15

    We revisited the implementation of 193 nm ultraviolet photodissociation (UVPD) within the ion cyclotron resonance (ICR) cell of a Fourier transform-ion cyclotron resonance (FT-ICR) mass spectrometer. UVPD performance characteristics were examined in the context of recent developments in the understanding of UVPD and in-cell tandem mass spectrometry. Efficient UVPD and photo-ECD of a model peptide and proteins within the ICR cell of a FT-ICR mass spectrometer are accomplished through appropriate modulation of laser pulse timing, relative to ion magnetron motion and the potential applied to an ion optical element upon which photons impinge. It is shown that UVPD yields efficient and extensive fragmentation, resulting in excellent sequence coverage for model peptide and protein cations.

  11. The Chemical Exhaust Hazards of Dichlorosilane Deposits Determined with FT-ICR Mass Spectrometry

    Energy Technology Data Exchange (ETDEWEB)

    JAREK, RUSSELL L.; THORNBERG, STEVEN M.

    1999-10-01

    Flammable deposits have been analyzed from the exhaust systems of tools employing dichlorosilane (DCS) as a processing gas. Exact mass determinations with a high-resolution Fourier-transform ion-cyclotron resonance (FT-ICR) mass spectrometer allowed the identification of various polysiloxane species present in such an exhaust flow. Ion-molecule reactions indicate the preferred reaction pathway of siloxane formation is through HCl loss, leading to the highly reactive polysiloxane that was detected in the flammable deposits.

  12. Electrospray ionization FT-ICR mass spectrometry of ARN naphthenic acids in crudes : preconcentration and quantification

    Energy Technology Data Exchange (ETDEWEB)

    Mapolelo, M.M.; Rodgers, R.P.; Marshall, A.G. [Florida State Univ., Tallahassee, FL (United States). Dept. of Chemistry and Biochemistry; Florida State Univ., Tallahassee, FL (United States). Cyclotron Resonance Program, National High Magnetic Field Laboratory

    2008-07-01

    The deposition of naphthenate solids and formation of sodium soaps in oil production equipment are known to create flow assurance problems for oilfield operators. Calcium naphthenate formation depends largely on tetraprotic naphthenic acids known as ARN acids in crude oil, whereas sodium naphthenates originate from less substituted lower molecular weight naphthenic acids. This study attempted to preconcentrate and quantify ARN-type acids in whole crude oils. Fourier transform ion cyclotron resonance (FT-ICR) mass spectroscopy (MS) provided detailed acidic speciation for all crudes and deposits analyzed. The preconcentration step involved bubbling ammonia into toluene-diluted crudes known to have ARN-type acids. ARN acids from the crystals increased from undetectable in the parent crude, to the most abundant acid species in the extract mass spectrum. A pure ARN acid standard was prepared for quantitation from successive cleaning and acid digestion of a naphthenate deposit. Analysis of the standard by negative-ion electrospray ionization (ESI) FT-ICR MS showed only ARN acid species. The paper described how API gravity, solvent systems and the paraffinic versus aromatic composition in the crude oil can influence crystal formation. Correlation of FT-ICR MS data of the respective crudes known to contain ARN acids naturally and crudes spiked with ARN acid standard were discussed and the significance of the preconcentration step was highlighted as a method to enhance the detection of ARN acids in crudes.

  13. Mass measurements on neutron-deficient nuclides at SHIPTRAP and commissioning of a cryogenic narrow-band FT-ICR mass spectrometer

    Energy Technology Data Exchange (ETDEWEB)

    Ferrer Garcia, R.

    2007-07-01

    The dissertation presented here deals with high-precision Penning trap mass spectrometry on short-lived radionuclides. Owed to the ability of revealing all nucleonic interactions, mass measurements far off the line of {beta}-stability are expected to bring new insight to the current knowledge of nuclear properties and serve to test the predictive power of mass models and formulas. In nuclear astrophysics, atomic masses are fundamental parameters for the understanding of the synthesis of nuclei in the stellar environments. This thesis presents ten mass values of radionuclides around A=90 interspersed in the predicted rp-process pathway. Six of them have been experimentally determined for the first time. The measurements have been carried out at the Penning-trap mass spectrometer SHIPTRAP using the destructive time-of-flight ion-cyclotron-resonance (TOF-ICR) detection technique. Given the limited performance of the TOF-ICR detection when trying to investigate heavy/superheavy species with small production cross sections ({sigma} <1 {mu}b), a new detection system is found to be necessary. Thus, the second part of this thesis deals with the commissioning of a cryogenic double-Penning trap system for the application of a highly-sensitive, narrow-band Fourier-transform ion-cyclotron-resonance (FT-ICR) detection technique. With the non-destructive FT-ICR detection method a single singly-charged trapped ion will provide the required information to determine its mass. First off-line tests of a new detector system based on a channeltron with an attached conversion dynode, of a cryogenic pumping barrier, to guarantee ultra-high vacuum conditions during mass determination, and of the detection electronics for the required single-ion sensitivity are reported. (orig.)

  14. Mass measurements on neutron-deficient nuclides at SHIPTRAP and commissioning of a cryogenic narrow-band FT-ICR mass spectrometer

    International Nuclear Information System (INIS)

    The dissertation presented here deals with high-precision Penning trap mass spectrometry on short-lived radionuclides. Owed to the ability of revealing all nucleonic interactions, mass measurements far off the line of β-stability are expected to bring new insight to the current knowledge of nuclear properties and serve to test the predictive power of mass models and formulas. In nuclear astrophysics, atomic masses are fundamental parameters for the understanding of the synthesis of nuclei in the stellar environments. This thesis presents ten mass values of radionuclides around A=90 interspersed in the predicted rp-process pathway. Six of them have been experimentally determined for the first time. The measurements have been carried out at the Penning-trap mass spectrometer SHIPTRAP using the destructive time-of-flight ion-cyclotron-resonance (TOF-ICR) detection technique. Given the limited performance of the TOF-ICR detection when trying to investigate heavy/superheavy species with small production cross sections (σ <1 μb), a new detection system is found to be necessary. Thus, the second part of this thesis deals with the commissioning of a cryogenic double-Penning trap system for the application of a highly-sensitive, narrow-band Fourier-transform ion-cyclotron-resonance (FT-ICR) detection technique. With the non-destructive FT-ICR detection method a single singly-charged trapped ion will provide the required information to determine its mass. First off-line tests of a new detector system based on a channeltron with an attached conversion dynode, of a cryogenic pumping barrier, to guarantee ultra-high vacuum conditions during mass determination, and of the detection electronics for the required single-ion sensitivity are reported. (orig.)

  15. Chemical characterization of synthetic cannabinoids by electrospray ionization FT-ICR mass spectrometry.

    Science.gov (United States)

    Kill, Jade B; Oliveira, Izabela F; Tose, Lilian V; Costa, Helber B; Kuster, Ricardo M; Machado, Leandro F; Correia, Radigya M; Rodrigues, Rayza R T; Vasconcellos, Géssica A; Vaz, Boniek G; Romão, Wanderson

    2016-09-01

    The synthetic cannabinoids (SCs) represent the most recent advent of the new psychotropic substances (NPS) and has become popularly known to mitigate the effects of the Δ(9)-THC. The SCs are dissolved in organic solvents and sprayed in a dry herbal blend. However, little information is reported on active ingredients of SCs as well as the excipients or diluents added to the herbal blend. In this work, the direct infusion electrospray ionization Fourier transform ion cyclotron mass spectrometry technique (ESI-FT-ICR MS) was applied to explore the chemical composition of nine samples of herbal extract blends, where a total of 11 SCs (UR-144, JWH-073, XLR-11, JWH-250, JWH-122, AM-2201, AKB48, JWH-210, JWH-081, MAM-2201 and 5F-AKB48) were identified in the positive ionization mode, ESI(+), and other 44 chemical species (saturated and unsaturated fatty acids, sugars, flavonoids, etc.) were detected in the negative ionization mode, ESI(-). Additionally, CID experiments were performed, and fragmentation pathways were proposed to identify the connectivity of SCs. Thus, the direct infusion ESI-FT-ICR MS technique is a powerful tool in forensic chemistry that enables the rapid and unequivocal way for the determination of molecular formula, the degree of unsaturation (DBE-double bond equivalent) and exact mass (<1ppm) of a total of 55 chemical species without the prior separation step. PMID:27471991

  16. Top-Down Mass Spectrometry Imaging of Intact Proteins by LAESI FT-ICR MS

    CERN Document Server

    Kiss, András; Reschke, Brent R; Powell, Matthew J; Heeren, Ron M A

    2013-01-01

    Laser Ablation Electrospray Ionization is a recent development in mass spectrometry imaging. It has been shown that lipids and small metabolites can be imaged in various samples such as plant material, tissue sections or bacterial colonies without anysample pre-treatment. Further, laser ablation electrospray ionization has been shown to produce multiply charged protein ions from liquids or solid surfaces. This presents a means to address one of the biggest challenges in mass spectrometry imaging; the identification of proteins directly from biological tissue surfaces. Such identification is hindered by the lack of multiply charged proteins in common MALDI ion sources and the difficulty of performing tandem MS on such large, singly charged ions. We present here top-down identification of intact proteins from tissue with a LAESI ion source combined with a hybrid ion-trap FT-ICR mass spectrometer. The performance of the system was first tested with a standard protein with ECD and IRMPD fragmentation to prove the...

  17. An investigation of emulsion interfacial material by ultrahigh resolution FT-ICR mass spectrometry

    Energy Technology Data Exchange (ETDEWEB)

    Ehrmann, B.M. [Florida State Univ., Tallahassee, FL (United States). Dept. of Chemistry and Biochemistry; Juyal, P. [Florida State Univ., Tallahassee, FL (United States). National High Magnetic Field Laboratory; Rodgers, R.P.; Marshall, A.G. [Florida State Univ., Tallahassee, FL (United States). Dept. of Chemistry and Biochemistry; Florida State Univ., Tallahassee, FL (United States). National High Magnetic Field Laboratory

    2008-07-01

    The formation of water-oil emulsions in crude oil poses a large problem for the petroleum industry because of the production losses and cost associated with chemicals used to break the emulsions. The species responsible for emulsion formation must therefore be identified and characterized. It has been suggested that asphaltenes absorb and accumulate at the emulsion water-oil interface and contribute to emulsion stability. However, studies have also shown that co-precipitated material may contribute to the stability of the water-oil emulsions. Fourier transform ion cyclotron resonance (FT-ICR) mass spectroscopy (MS) analysis of the acidic portion of interfacial material has revealed that it is also enriched in specific Ox and SOx species relative to the parent crude. The similarity between the co-precipitate and isolated interfacial material suggests that naphthenic acids strongly interact with the asphaltenes. As a result, they co-precipitate with them even though naphthenic acids alone are soluble in n-heptane. This study characterized the interfacial material and a crude oil known to cause emulsions in the field. The basic, acidic, and aromatic species in the isolated interfacial material and parent crude were highlighted by positive/negative electrospray ionization and atmospheric pressure photoionization (APPI) high resolution Fourier transform ion cyclotron resonance (FT-ICR) mass spectrometry. The composition of the interfacial material was also investigated. An attempt was made to regenerate the emulsion after isolation, in the absence of the parent crude. Once the emulsion was formed, the isolated interfacial material was analyzed to determine the minimum components required to form a stable emulsion. This provided a direct comparison between the species identified in the interfacial material and those that interact with the asphaltene fraction of the crude oil.

  18. 2D FT-ICR MS of Calmodulin: A Top-Down and Bottom-Up Approach

    Science.gov (United States)

    Floris, Federico; van Agthoven, Maria; Chiron, Lionel; Soulby, Andrew J.; Wootton, Christopher A.; Lam, Yuko P. Y.; Barrow, Mark P.; Delsuc, Marc-André; O'Connor, Peter B.

    2016-09-01

    Two-dimensional Fourier transform ion cyclotron resonance mass spectrometry (2D FT-ICR MS) allows data-independent fragmentation of all ions in a sample and correlation of fragment ions to their precursors through the modulation of precursor ion cyclotron radii prior to fragmentation. Previous results show that implementation of 2D FT-ICR MS with infrared multi-photon dissociation (IRMPD) and electron capture dissociation (ECD) has turned this method into a useful analytical tool. In this work, IRMPD tandem mass spectrometry of calmodulin (CaM) has been performed both in one-dimensional and two-dimensional FT-ICR MS using a top-down and bottom-up approach. 2D IRMPD FT-ICR MS is used to achieve extensive inter-residue bond cleavage and assignment for CaM, using its unique features for fragment identification in a less time- and sample-consuming experiment than doing the same thing using sequential MS/MS experiments.

  19. Molecular characterization and comparison of shale oils generated by different pyrolysis methods using FT-ICR mass spectrometry

    Science.gov (United States)

    Jin, J.M.; Kim, S.; Birdwell, J.E.

    2011-01-01

    Fourier transform ion cyclotron resonance mass spectrometry (FT ICR-MS) was applied in the analysis of shale oils generated using two different pyrolysis systems under laboratory conditions meant to simulate surface and in situ oil shale retorting. Significant variations were observed in the shale oils, particularly the degree of conjugation of the constituent molecules. Comparison of FT ICR-MS results to standard oil characterization methods (API gravity, SARA fractionation, gas chromatography-flame ionization detection) indicated correspondence between the average Double Bond Equivalence (DBE) and asphaltene content. The results show that, based on the average DBE values and DBE distributions of the shale oils examined, highly conjugated species are enriched in samples produced under low pressure, high temperature conditions and in the presence of water.

  20. Studies on Triterpenoids and Flavones in Glycyrrhiza uralensis Fisch. By HPLC-ESI-MSn and FT-ICR-MSn

    Institute of Scientific and Technical Information of China (English)

    MENG Xiangyu; LI Huilin; SONG Fengrui; LIU Chunming; LIU Zhiqiang; LIU Shuying

    2009-01-01

    Seven compounds, four flavones and three triterpenoids from Glycyrrhiza uralensis Fisch. Extract are identified by high performance liquid chromatography coupled with electrospray ionization multi-tandem mass spectrometry (HPLC-ESI-MSn). The fragmentation pathways of these compounds are investigated by ESI-MSn and Fourier transform ion cyclotron resonance multiple-stage tandem mass spectrometry (FT-ICR-MSn). Comparing the reten-tion times (tR) and mass spectra with those of reference compounds, seven components are identified in Glycyrrhiza uralensis Fisch. And their MSn data proposed plausible schemes for their fragmentation. All the experimental results show that ESI-MSn and FT-ICR-MSn are powerful tools for the structural characterization of triterpenoids and fla-vones.

  1. High Mass Accuracy and High Mass Resolving Power FT-ICR Secondary Ion Mass Spectrometry for Biological Tissue Imaging

    CERN Document Server

    Smith, Donald F; Leach, Franklin E; Robinson, Errol W; Paša-Tolić, Ljiljana; Heeren, Ron M A

    2013-01-01

    Biological tissue imaging by secondary ion mass spectrometry has seen rapid development with the commercial availability of polyatomic primary ion sources. Endogenous lipids and other small bio-molecules can now be routinely mapped on the sub-micrometer scale. Such experiments are typically performed on time-of-flight mass spectrometers for high sensitivity and high repetition rate imaging. However, such mass analyzers lack the mass resolving power to ensure separation of isobaric ions and the mass accuracy for elemental formula assignment based on exact mass measurement. We have recently reported a secondary ion mass spectrometer with the combination of a C60 primary ion gun with a Fourier transform ion cyclotron resonance mass spectrometer (FT-ICR MS) for high mass resolving power, high mass measurement accuracy and tandem mass spectrometry capabilities. In this work, high specificity and high sensitivity secondary ion FT-ICR MS was applied to chemical imaging of biological tissue. An entire rat brain tissu...

  2. Distributed computing strategies for processing of FT-ICR MS imaging datasets for continuous mode data visualization

    Energy Technology Data Exchange (ETDEWEB)

    Smith, Donald F.; Schulz, Carl; Konijnenburg, Marco; Kilic, Mehmet; Heeren, Ronald M.

    2015-03-01

    High-resolution Fourier transform ion cyclotron resonance (FT-ICR) mass spectrometry imaging enables the spatial mapping and identification of biomolecules from complex surfaces. The need for long time-domain transients, and thus large raw file sizes, results in a large amount of raw data (“big data”) that must be processed efficiently and rapidly. This can be compounded by largearea imaging and/or high spatial resolution imaging. For FT-ICR, data processing and data reduction must not compromise the high mass resolution afforded by the mass spectrometer. The continuous mode “Mosaic Datacube” approach allows high mass resolution visualization (0.001 Da) of mass spectrometry imaging data, but requires additional processing as compared to featurebased processing. We describe the use of distributed computing for processing of FT-ICR MS imaging datasets with generation of continuous mode Mosaic Datacubes for high mass resolution visualization. An eight-fold improvement in processing time is demonstrated using a Dutch nationally available cloud service.

  3. Distributed computing strategies for processing of FT-ICR MS imaging datasets for continuous mode data visualization.

    Science.gov (United States)

    Smith, Donald F; Schulz, Carl; Konijnenburg, Marco; Kilic, Mehmet; Heeren, Ron M A

    2015-03-01

    High-resolution Fourier transform ion cyclotron resonance (FT-ICR) mass spectrometry imaging enables the spatial mapping and identification of biomolecules from complex surfaces. The need for long time-domain transients, and thus large raw file sizes, results in a large amount of raw data ("big data") that must be processed efficiently and rapidly. This can be compounded by large-area imaging and/or high spatial resolution imaging. For FT-ICR, data processing and data reduction must not compromise the high mass resolution afforded by the mass spectrometer. The continuous mode "Mosaic Datacube" approach allows high mass resolution visualization (0.001 Da) of mass spectrometry imaging data, but requires additional processing as compared to feature-based processing. We describe the use of distributed computing for processing of FT-ICR MS imaging datasets with generation of continuous mode Mosaic Datacubes for high mass resolution visualization. An eight-fold improvement in processing time is demonstrated using a Dutch nationally available cloud service.

  4. High field FT-ICR mass spectrometry for molecular characterization of snow board from Moscow regions.

    Science.gov (United States)

    Mazur, Dmitry M; Harir, Mourad; Schmitt-Kopplin, Philippe; Polyakova, Olga V; Lebedev, Albert T

    2016-07-01

    High field Fourier transform ion cyclotron resonance (FT-ICR) mass spectrometry analysis of eight snow samples from Moscow city allowed us to identify more than 2000 various elemental compositions corresponding to regional air pollutants. The hierarchical cluster analysis (HCA) of the data showed good concordance of three main groups of samples with the main wind directions. The North-West group (A1) is represented by several homologous CHOS series of aliphatic organic aerosols. They may form as a result of enhanced photochemical reactions including oxidation of hydrocarbons with sulfonations due to higher amount of SO2 emissions in the atmosphere in this region. Group A2, corresponding to the South-East part of Moscow, contains large amount of oxidized hydrocarbons of different sources that may form during oxidation in atmosphere. These hydrocarbons appear correlated to emissions from traffic, neighboring oil refinery, and power plants. Another family of compounds specific for this region involves CHNO substances formed during oxidation processes including NOx and NO3 radical since emissions of NOx are higher in this part of the city. Group A3 is rich in CHO type of compounds with high H/C and low O/C ratios, which is characteristic of oxidized hydrocarbon-like organic aerosol. CHNO types of compounds in A3 group are probably nitro derivatives of condensed hydrocarbons such as PAH. This non-targeted profiling revealed site specific distribution of pollutants and gives a chance to develop new strategies in air quality control and further studies of Moscow environment. PMID:26994789

  5. TG/DTG, FT-ICR Mass Spectrometry, and NMR Spectroscopy Study of Heavy Fuel Oil

    KAUST Repository

    Elbaz, Ayman M.

    2015-11-12

    There is an increasing interest in the comprehensive study of heavy fuel oil (HFO) due to its growing use in furnaces, boilers, marines, and recently in gas turbines. In this work, the thermal combustion characteristics and chemical composition of HFO were investigated using a range of techniques. Thermogravimetric analysis (TGA) was conducted to study the nonisothermal HFO combustion behavior. Chemical characterization of HFO was accomplished using various standard methods in addition to direct infusion atmospheric pressure chemical ionization Fourier transform ion cyclotron resonance mass spectrometry (APCI-FTICR MS), high resolution 1H nuclear magnetic resonance (NMR), 13C NMR, and two-dimensional heteronuclear multiple bond correlation (HMBC) spectroscopy. By analyzing thermogravimetry and differential thermogravimetry (TG/DTG) results, three different reaction regions were identified in the combustion of HFO with air, specifically, low temperature oxidation region (LTO), fuel deposition (FD), and high temperature oxidation (HTO) region. At the high end of the LTO region, a mass transfer resistance (skin effect) was evident. Kinetic analysis in LTO and HTO regions was conducted using two different kinetic models to calculate the apparent activation energy. In both models, HTO activation energies are higher than those for LTO. The FT-ICR MS technique resolved thousands of aromatic and sulfur containing compounds in the HFO sample and provided compositional details for individual molecules of three major class species. The major classes of compounds included species with one sulfur atom (S1), with two sulfur atoms (S2), and purely hydrocarbons (HC). The DBE (double bond equivalent) abundance plots established for S1 and HC provided additional information on their distributions in the HFO sample. The 1H NMR and 13C NMR results revealed that nearly 59% of the 1H nuclei were distributed as paraffinic CH2 and 5% were in aromatic groups. Nearly 21% of 13C nuclei were

  6. Dissolved organic carbon (DOC) in soil extracts investigated by FT-ICR-MS

    Science.gov (United States)

    Hofmann, D.; Steffen, D.; Jablonowski, N. D.; Burauel, P.

    2012-04-01

    Soil drying and rewetting usually increases the release of xenobiotics like pesticides present in agricultural soils. Besides the effect on the release of two aged 14C-labeled pesticide residues we focus on the characterisation of simultaneously remobilized dissolved organic carbon (DOC) to gain new insights into structure and stability aspects of soil organic carbon fractions. The test soil (gleyic cambisol; Corg 1.2%, pH 7.2) was obtained from the upper soil layer of two individual outdoor lysimeter studies containing either environmentally long-term aged 14C residues of the herbicide ethidimuron (0-10 cm depth; time of aging: 9 years) or methabenzthiazuron (0-30 cm depth; time of aging: 17 years). Soil samples (10 g dry soil equivalents) were (A=dry/wet) previously dried (45°C) or (B=wet/wet) directly mixed with pure water (1+2, w:w), shaken (150 rpm, 1 h), and centrifuged (2000 g). This extraction procedure was repeated several individual times, for both setups. The first three individual extractions, respectively were used for further investigations. Salt was removed from samples prior analysis because of a possible quench effect in the electrospray (ESI) source by solid phase extraction (SPE) with Chromabond C18 Hydra-cartridges (Macherey-Nagel) and methanol as backextraction solvent. The so preconcentrated and desalted samples were introduced by flow injection analysis (FIA) in a fourier transform ion cyclotron resonance mass spectrometer (FT-ICR-MS), equipped with an ESI source and a 7 T supra-conducting magnet (LTQ-FT Ultra, ThermoFisher Scientific). This technique is the key technique for complex natural systems attributed by their outstanding mass resolution (used 400.000 at m/z 400 Da) and mass accuracy (≤ 1ppm) by simultaneously providing molecular level details of thousands of compounds and was successful applied for the investigations of natural organic matter (NOM) different sources like marine and surface water, soil, sediment, bog and crude oil

  7. Silicon micromachined broad band light source

    Science.gov (United States)

    George, Thomas (Inventor); Jones, Eric (Inventor); Tuma, Margaret L. (Inventor); Eastwood, Michael (Inventor); Hansler, Richard (Inventor)

    2004-01-01

    A micro electromechanical system (MEMS) broad band incandescent light source includes three layers: a top transmission window layer; a middle filament mount layer; and a bottom reflector layer. A tungsten filament with a spiral geometry is positioned over a hole in the middle layer. A portion of the broad band light from the heated filament is reflective off the bottom layer. Light from the filament and the reflected light of the filament are transmitted through the transmission window. The light source may operate at temperatures of 2500 K or above. The light source may be incorporated into an on board calibrator (OBC) for a spectrometer.

  8. Gas Chromatography Coupled to Atmospheric Pressure Chemical Ionization FT-ICR Mass Spectrometry for Improvement of Data Reliability.

    Science.gov (United States)

    Schwemer, Theo; Rüger, Christopher P; Sklorz, Martin; Zimmermann, Ralf

    2015-12-15

    Atmospheric pressure chemical ionization (APCI) offers the advantage of molecular ion information with low fragmentation. Hyphenating APCI to gas chromatography (GC) and ultrahigh resolution mass spectrometry (FT-ICR MS) enables an improved characterization of complex mixtures. Data amounts acquired by this system are very huge, and existing peak picking algorithms are usually extremely time-consuming, if both gas chromatographic and ultrahigh resolution mass spectrometric data are concerned. Therefore, automatic routines are developed that are capable of handling these data sets and further allow the identification and removal of known ionization artifacts (e.g., water- and oxygen-adducts, demethylation, dehydrogenation, and decarboxylation). Furthermore, the data quality is enhanced by the prediction of an estimated retention index, which is calculated simply from exact mass data combined with a double bond equivalent correction. This retention index is used to identify mismatched elemental compositions. The approach was successfully tested for analysis of semivolatile components in heavy fuel oil and diesel fuel as well as primary combustion particles emitted by a ship diesel research engine. As a result, 10-28% of the detected compounds, mainly low abundant species, classically assigned by using only the mass spectrometric information, were identified as not valid and removed. Although GC separation is limited by the slow acquisition rate of the FT-ICR MS (information.

  9. The GREGOR Broad-Band Imager

    Science.gov (United States)

    von der Lühe, O.; Volkmer, R.; Kentischer, T. J.; Geißler, R.

    2012-11-01

    The design and characteristics of the Broad-Band Imager (BBI) of GREGOR are described. BBI covers the visible spectral range with two cameras simultaneously for a large field and with critical sampling at 390 nm, and it includes a mode for observing the pupil in a Foucault configuration. Samples of first-light observations are shown.

  10. Broad-band acoustic hyperbolic metamaterial

    CERN Document Server

    Shen, Chen; Sui, Ni; Wang, Wenqi; Cummer, Steven A; Jing, Yun

    2015-01-01

    Acoustic metamaterials (AMMs) are engineered materials, made from subwavelength structures, that exhibit useful or unusual constitutive properties. There has been intense research interest in AMMs since its first realization in 2000 by Liu et al. A number of functionalities and applications have been proposed and achieved using AMMs. Hyperbolic metamaterials are one of the most important types of metamaterials due to their extreme anisotropy and numerous possible applications, including negative refraction, backward waves, spatial filtering, and subwavelength imaging. Although the importance of acoustic hyperbolic metamaterials (AHMMs) as a tool for achieving full control of acoustic waves is substantial, the realization of a broad-band and truly hyperbolic AMM has not been reported so far. Here, we demonstrate the design and experimental characterization of a broadband AHMM that operates between 1.0 kHz and 2.5 kHz.

  11. Utilizing a Robotic Sprayer for High Lateral and Mass Resolution MALDI FT-ICR MSI of Microbial Cultures

    Energy Technology Data Exchange (ETDEWEB)

    Anderton, Christopher R.; Chu, Rosalie K.; Tolic, Nikola; Creissen, Alain V.; Pasa-Tolic, Ljiljana

    2016-01-07

    The ability to visualize biochemical interactions between microbial communities using MALDI MSI has provided tremendous insights into a variety of biological fields. Matrix application using a sieve proved to be incredibly useful, but it had many limitations that include uneven matrix coverage and limitation in the types of matrices one could employ in their studies. Recently, there has been a concerted effort to improve matrix application for studying agar plated microbial cultures, many of which utilized automated matrix sprayers. Here, we describe the usefulness of using a robotic sprayer for matrix application. The robotic sprayer has two-dimensional control over where matrix is applied and a heated capillary that allows for rapid drying of the applied matrix. This method provided a significant increase in MALDI sensitivity over the sieve method, as demonstrated by FT-ICR MS analysis, facilitating the ability to gain higher lateral resolution MS images of Bacillus Subtilis than previously reported. This method also allowed for the use of different matrices to be applied to the culture surfaces.

  12. Oligomers, organosulfates, and nitrooxy organosulfates in rainwater identified by ultra-high resolution electrospray ionization FT-ICR mass spectrometry

    Directory of Open Access Journals (Sweden)

    K. E. Altieri

    2009-04-01

    Full Text Available Wet deposition is an important removal mechanism for atmospheric organic matter, and a potentially important input for receiving ecosystems, yet less than 50% of rainwater organic matter is considered chemically characterized. Precipitation samples collected in New Jersey, USA, were analyzed by negative ion ultra-high resolution electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS. Elemental compositions of 552 unique molecular species were determined in the mass range 50–500 Da in the rainwater. Four main groups of organic compounds were identified: compounds containing carbon, hydrogen, and oxygen (CHO only, sulfur (S containing CHOS compounds, nitrogen (N containing CHON compounds, and S- and N- containing CHONS compounds. Organic acids commonly identified in precipitation were detected in the rainwater. Within the four main groups of compounds detected in the rainwater, oligomers, organosulfates, and nitrooxy-organosulfates were assigned based on elemental formula comparisons. The majority of the compounds identified are products of atmospheric reactions and are known contributors to secondary organic aerosol (SOA formed from gas phase, aerosol phase, and in-cloud reactions in the atmosphere. It is suggested that the large uncharacterized component of SOA is the main contributor to the large uncharacterized component of rainwater organic matter.

  13. Oligomers, organosulfates, and nitrooxy organosulfates in rainwater identified by ultra-high resolution electrospray ionization FT-ICR mass spectrometry

    Science.gov (United States)

    Altieri, K. E.; Turpin, B. J.; Seitzinger, S. P.

    2009-04-01

    Wet deposition is an important removal mechanism for atmospheric organic matter, and a potentially important input for receiving ecosystems, yet less than 50% of rainwater organic matter is considered chemically characterized. Precipitation samples collected in New Jersey, USA, were analyzed by negative ion ultra-high resolution electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS). Elemental compositions of 552 unique molecular species were determined in the mass range 50-500 Da in the rainwater. Four main groups of organic compounds were identified: compounds containing carbon, hydrogen, and oxygen (CHO) only, sulfur (S) containing CHOS compounds, nitrogen (N) containing CHON compounds, and S- and N- containing CHONS compounds. Organic acids commonly identified in precipitation were detected in the rainwater. Within the four main groups of compounds detected in the rainwater, oligomers, organosulfates, and nitrooxy-organosulfates were assigned based on elemental formula comparisons. The majority of the compounds identified are products of atmospheric reactions and are known contributors to secondary organic aerosol (SOA) formed from gas phase, aerosol phase, and in-cloud reactions in the atmosphere. It is suggested that the large uncharacterized component of SOA is the main contributor to the large uncharacterized component of rainwater organic matter.

  14. High molecular weight SOA formation during limonene ozonolysis: insights from ultrahigh-resolution FT-ICR mass spectrometry characterization

    Science.gov (United States)

    Kundu, S.; Fisseha, R.; Putman, A. L.; Rahn, T. A.; Mazzoleni, L. R.

    2012-06-01

    The detailed molecular composition of laboratory generated limonene ozonolysis secondary organic aerosol (SOA) was studied using ultrahigh-resolution Fourier transform ion cyclotron resonance (FT-ICR) mass spectrometry. Approximately 1200 molecular formulas were identified in the SOA over the mass range of 140 to 850 Da. Four characteristic groups of high relative abundance species were observed; they indicate an array of accretion products that retain a large fraction of the limonene skeleton. The identified molecular formulas of each of the groups are related to one another by CH2, O and CH2O homologous series. The CH2 and O homologous series of the low molecular weight (MW) SOA (m/z 300) were found to constitute a significant number fraction of the identified SOA components. The formation of high MW compounds was evaluated by molecular formula trends, fragmentation analysis of select high MW compounds and a comprehensive reaction matrix including the identified low MW SOA, hydroperoxides and Criegee radicals as building blocks. Although the formation of high MW SOA may occur via a variety of radical and non-radical reaction channels, the combined approach indicates a greater importance of the non-condensation reactions over aldol and ester condensation reaction channels. Among these hemi-acetal reactions appear to be most dominant followed by hydroperoxide and Criegee reaction channels.

  15. Comparison of collision-induced dissociation and electron-induced dissociation of phillyrin using FT-ICR MS

    Science.gov (United States)

    Lin, Zhenguang; Lin, Zhiwei; Mu, Yingdi; Yan, Dong

    2016-10-01

    Electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry using collision-induced dissociation (CID) and electron capture dissociation (ECD) at high mass resolution was first applied to investigate the characteristic fragment ions of phillyrin. The CID experimental results demonstrated the elemental composition of fragment ions unambiguously, so a reasonable fragmentation pathway of phillyrin was proposed. The ECD fragmentation mechanism was believed to be fundamentally different from the CID method. ECD could be used not only in the biological field but also as a powerful complement to the structural identification of small molecular compounds. The characteristic fragmentation pathways were helpful in analyzing and interpreting the stability and property of the parent ion. The ESI FT-ICR MS using CID and ECD methods was applied to investigate the characteristic fragment ions of Phillyrin for the first time. The fragmentation process of phillyrin which formation of the peroxide bond by CID, was discussed in detail. These characteristic fragmentation pathways were helpful to analyze and interpret the stability and property of the parent ion. It was clearly demonstrated that ECD can be not only used to Biological field but also a powerful complement to the structure identification of small molecules.

  16. Chemical Composition and Potential Environmental Impacts of Water-Soluble Polar Crude Oil Components Inferred from ESI FT-ICR MS

    OpenAIRE

    Liu, Yina; Kujawinski, Elizabeth B.

    2015-01-01

    Polar petroleum components enter marine environments through oil spills and natural seepages each year. Lately, they are receiving increased attention due to their potential toxicity to marine organisms and persistence in the environment. We conducted a laboratory experiment and employed state-of-the-art Fourier-transform ion cyclotron resonance mass spectrometry (FT-ICR-MS) to characterize the polar petroleum components within two operationally-defined seawater fractions: the water-soluble f...

  17. High-field FT-ICR-MS and aromaticity equivalent approach for structural identification of water soluble organic compounds (WSOC)

    Science.gov (United States)

    Harir, Mourad; Yassine, Mahmoud M.; Dabek-Zlotorzynska, Ewa; Hertkorn, Norbert; Schmitt-Kopplin, Philippe

    2015-04-01

    Organic aerosol (OA) makes up a large and often dominant fraction, (20 to 90%) of the submicron atmospheric particulate mass, and its effects are becoming increasingly important in determining climatic and health effects of atmospheric aerosols. Despite the abundance of OA, our understanding of the sources, formation processes and atmospheric properties of OA is limited. Atmospheric OA has both primary (directly emitted) and secondary (formed in the atmosphere from precursor gases) sources, which can be natural (e.g. vegetation) and/or anthropogenic (e.g. fossil-based vehicle exhaust or biomass burning). A significant fraction of OA contains as much as 20-70% of water soluble organic compounds (WSOC). The WSOC fraction is a very complex mixture of low volatility, polyfunctional aliphatic and aromatic compounds containing carboxyl, alcohol, carbonyl, sulfo, nitro, and other functionalities. This high degree of chemical complexity of atmospheric organics has inspired a number of sophisticated approaches that are capable of identifying and detecting a variety of different analytes in OA. Accordingly, one of the most challenging areas of atmospheric particulate matter (PM) analysis is to comprehend the molecular complexity of the OA, especially WSOC fraction, a significant component of atmospheric fine PM (PM2.5). The sources of WSOC are not well understood, especially the relative contributions of primary vs. secondary organic aerosol. Therefore, the molecular characterization of WSOC is important because it allows gaining insight into aerosol sources and underlying mechanisms of secondary organic aerosols (SOA) formation and transformation. In this abstract, molecular characterization of WSOC was achieved using high-field mass spectrometry FT-ICR-MS and aromaticity equivalent approach. Aromaticity equivalent (Xc), defined recently as a new parameter calculated from the assigned molecular formulas (complementary to the aromaticity index [1]), is introduced to improve

  18. High molecular weight SOA formation during limonene ozonolysis: insights from ultrahigh-resolution FT-ICR mass spectrometry characterization

    Directory of Open Access Journals (Sweden)

    S. Kundu

    2012-01-01

    Full Text Available The detailed molecular composition of secondary organic aerosols (SOA from limonene ozonolysis was studied using ultrahigh-resolution Fourier transform ion cyclotron resonance (FT-ICR mass spectrometry. High molecular weight (MW compounds (m/z > 300 were found to constitute a significant number fraction of the identified SOA components. Double bond equivalents (DBE = the number of rings plus the number of double bonds increased with MW. The O:C ratios and relative abundances of compounds decreased with increasing MW. The mass spectra of limonene contain 4 distinct clusters of negative ions: Group I (140 < m/z < 300, Group II (300 < m/z < 500, Group III (500 < m/z < 700 and Group IV (700 < m/z < 850. A number of CH2 and O homologous series of low MW SOA (Group 1 with carbon number 7–15 and oxygen number 3–9 were observed. Their occurrence can be explained with isomerization and elimination reactions of Criegee radicals, reactions between alkyl peroxy radicals, and scission of alkoxy radicals resulting from the Criegee radicals. Additionally, fragmentation analysis and observations of formaldehyde homologous series provide evidence for aerosol growth by the reactive uptake of generated gas-phase carbonyls in limonene ozonolysis. The decreasing O:C ratios between group of compounds indicated the importance of condensation (aldol and esterification reaction pathways for high MW compound formation. However, the prominent DBE changes of 2 between the groups of compounds and selected fragmentation (MS/MS analysis of Group II and Group III ions indicated a predominance of non-condensation (hydroperoxide, Criegee and hemi-acetal reaction pathways. A reaction matrix created with the combination of low MW SOA, hydroperoxides, and Criegee radicals indicated higher frequencies for the hemi-acetal and condensation reaction pathways. Overall, the combined approach confirms the importance of non

  19. High molecular weight SOA formation during limonene ozonolysis: insights from ultrahigh-resolution FT-ICR mass spectrometry characterization

    Directory of Open Access Journals (Sweden)

    S. Kundu

    2012-06-01

    Full Text Available The detailed molecular composition of laboratory generated limonene ozonolysis secondary organic aerosol (SOA was studied using ultrahigh-resolution Fourier transform ion cyclotron resonance (FT-ICR mass spectrometry. Approximately 1200 molecular formulas were identified in the SOA over the mass range of 140 to 850 Da. Four characteristic groups of high relative abundance species were observed; they indicate an array of accretion products that retain a large fraction of the limonene skeleton. The identified molecular formulas of each of the groups are related to one another by CH2, O and CH2O homologous series. The CH2 and O homologous series of the low molecular weight (MW SOA (m/z < 300 are explained with a combination of functionalization and fragmentation of radical intermediates and reactive uptake of gas-phase carbonyls. They include isomerization and elimination reactions of Criegee radicals, reactions between alkyl peroxy radicals, and scission of alkoxy radicals resulting from the Criegee radicals. The presence of compounds with 10–15 carbon atoms in the first group (e.g. C11H18O6 provides evidence for SOA formation by the reactive uptake of gas-phase carbonyls during limonene ozonolysis. The high MW compounds (m/z > 300 were found to constitute a significant number fraction of the identified SOA components. The formation of high MW compounds was evaluated by molecular formula trends, fragmentation analysis of select high MW compounds and a comprehensive reaction matrix including the identified low MW SOA, hydroperoxides and Criegee radicals as building blocks. Although the formation of high MW SOA may occur via a variety of radical and non-radical reaction channels, the combined approach indicates a greater importance of the non-condensation reactions over aldol and ester condensation reaction channels. Among these hemi-acetal reactions appear to be most

  20. Molecular characterisation of soil organic matter by laser-desorption ionization Fourier-transform ion cyclotron resonance mass spectrometry (LDI-FT-ICR-MS)

    Science.gov (United States)

    Abiven, S.; Fuchser, J.; Schmidt, M. W. I.; Dittmar, T.

    2012-04-01

    Soil organic matter (SOM) characterisation has been an analytical challenge for decades. On one hand, methods like humic substances extraction describe large pools of molecules, but these extractions target operationnally- rather than chemically-defined pools. On the other hand, specific compound analysis provides a more precise overview on the molecules present in the soil, but the sum of these molecules represents only a minor portion of the soil organic matter. Despite these shortcomings, soil organic matter characterisation is used in many concepts of soil science. For example, the soil aggregation hierarchical model describes the physical organisation of soils into fractions bound together by organic matter of different quality for each size fraction. Due to the method inadequation, most of these concepts still need to be validated. We took advantage of a unique analytical set-up coupling laser-desorption ionization (LDI) to ultrahigh-resolution mass spectrometry via the Fourier-transform ion cyclotron resonance technique (FT-ICR-MS) to further characterise soil organic matter and to validate the soil aggregation hierarchical model. Soil aggregates (3-5 mm) were collected from two soils, a cambisol (32 % clay, 4.2 %C), and a loess-derived soil (15% clay, 1.6 %C). Aggregates were fractionated by fast wetting into 250 μm fractions. These fractions were air-dried and ground to powder prior to analysis. LDI-FT-ICR-MS analyses were performed on otherwise untreated samples. Thousands of molecular formulae were identified in each samples, many of them could be associated with polyphenolic structures. The combination of LDI with ultrahigh-resolution FT-ICR-MS offers fundmentally new insights into soil organic matter, one of the largest organic matter pools on Earth.

  1. Functional Groups and Structural Insights of Water-Soluble Organic Carbon using Ultrahigh Resolution FT-ICR Tandem Mass Spectrometry

    Science.gov (United States)

    Mazzoleni, L. R.; Habib, D.; Zhao, Y.; Dalbec, M.; Samburova, V.; Hallar, G.; Zielinska, B.; Lowenthal, D.

    2013-12-01

    Water-soluble organic carbon (WSOC) is a complex mixture of thousands of organic compounds which may have significant influence on the climate-relevant properties of atmospheric aerosols. An improved understanding of the molecular composition of WSOC is needed to evaluate the effect of aerosol composition upon aerosol physical properties. Products of gas phase, aqueous phase and particle phase reactions contribute to pre-existing aerosol organic mass or nucleate new aerosol particles. Thus, ambient aerosols carry a complex array of WSOC components with variable chemical signatures depending upon its origin and aerosol life-cycle processes. In this work, ultrahigh resolution Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS) was used to characterize aerosol WSOC collected during the summer of 2010 at the Storm Peak Laboratory (3210 m a.s.l.) near Steamboat Springs, CO. Approximately 4000 molecular formulas were assigned in the mass range of m/z 100-800 after negative-ion electrospray ionization. The observed trends indicate significant non-oxidative accretion reaction pathways for the formation of high molecular weight WSOC components closely associated with terpene ozonolysis secondary organic aerosol (SOA). The aerosol WSOC was further characterized using ultrahigh resolution tandem MS analysis with infrared multiphoton dissociation to determine the functional groups and structural properties of 1700 WSOC species up to m/z 600. Due to the complex nature of the WSOC, multiple precursor ions were simultaneously fragmented. The exact mass measurements of the precursor and product ions facilitated molecular formula assignments and matching of neutral losses. The most important neutral losses are CO2, H2O, CH3OH, HNO3, CH3NO3, SO3 and SO4. The presence and frequency of these losses indicate the type of functional groups contained in the precursor structures. Consistent with the acidic nature of WSOC compounds, the most frequently observed losses

  2. Characterization of chemical constituents in Rhodiola Crenulate by high-performance liquid chromatography coupled with Fourier-transform ion cyclotron resonance mass spectrometer (HPLC-FT-ICR MS).

    Science.gov (United States)

    Han, Fei; Li, Yanting; Mao, Xinjuan; Xu, Rui; Yin, Ran

    2016-05-01

    In this work, an approach using high-performance liquid chromatography coupled with diode-array detection and Fourier-transform ion cyclotron resonance mass spectrometer (HPLC-FT-ICR MS) for the identification and profiling of chemical constituents in Rhodiola crenulata was developed for the first time. The chromatographic separation was achieved on an Inertsil ODS-3 column (150 mm × 4.6 mm,3 µm) using a gradient elution program, and the detection was performed on a Bruker Solarix 7.0 T mass spectrometer equipped with electrospray ionization source in both positive and negative modes. Under the optimized conditions, a total of 48 chemical compounds, including 26 alcohols and their glycosides, 12 flavonoids and their glycosides, 5 flavanols and gallic acid derivatives, 4 organic acids and 1 cyanogenic glycoside were identified or tentatively characterized. The results indicated that the developed HPLC-FT-ICR MS method with ultra-high sensitivity and resolution is suitable for identifying and characterizing the chemical constituents in R. crenulata. And it provides a helpful chemical basis for further research on R. crenulata. Copyright © 2016 John Wiley & Sons, Ltd.

  3. Epitope mapping of 7S cashew antigen in complex with antibody by solution-phase H/D exchange monitored by FT-ICR mass spectrometry.

    Science.gov (United States)

    Guan, Xiaoyan; Noble, Kyle A; Tao, Yeqing; Roux, Kenneth H; Sathe, Shridhar K; Young, Nicolas L; Marshall, Alan G

    2015-06-01

    The potential epitope of a recombinant food allergen protein, cashew Ana o 1, reactive to monoclonal antibody, mAb 2G4, has been mapped by solution-phase amide backbone H/D exchange (HDX) monitored by Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS). Purified mAb 2G4 was incubated with recombinant Ana o 1 (rAna o 1) to form antigen:monoclonal antibody (Ag:mAb) complexes. Complexed and uncomplexed (free) rAna o 1 were then subjected to HDX-MS analysis. Five regions protected from H/D exchange upon mAb binding are identified as potential conformational epitope-contributing segments. PMID:26169135

  4. Rapid Screening for Potential Epitopes Reactive with a Polycolonal Antibody by Solution-Phase H/D Exchange Monitored by FT-ICR Mass Spectrometry

    Science.gov (United States)

    Zhang, Qian; Noble, Kyle A.; Mao, Yuan; Young, Nicolas L.; Sathe, Shridhar K.; Roux, Kenneth H.; Marshall, Alan G.

    2013-07-01

    The potential epitopes of a recombinant food allergen protein, cashew Ana o 2, reactive to polyclonal antibodies, were mapped by solution-phase amide backbone H/D exchange (HDX) coupled with Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS). Ana o 2 polyclonal antibodies were purified in the serum from a goat immunized with cashew nut extract. Antibodies were incubated with recombinant Ana o 2 (rAna o 2) to form antigen:polyclonal antibody (Ag:pAb) complexes. Complexed and uncomplexed (free) rAna o 2 were then subjected to HDX-MS analysis. Four regions protected from H/D exchange upon pAb binding are identified as potential epitopes and mapped onto a homologous model.

  5. Infrared Matrix-Assisted Laser Desorption Electrospray Ionization (IR-MALDESI) Imaging Source Coupled to a FT-ICR Mass Spectrometer

    Science.gov (United States)

    Robichaud, Guillaume; Barry, Jeremy A.; Garrard, Kenneth P.; Muddiman, David C.

    2013-01-01

    Mass spectrometry imaging (MSI) allows for the direct monitoring of the abundance and spatial distribution of chemical compounds over the surface of a tissue sample. This technology has opened the field of mass spectrometry to numerous innovative applications over the past 15 years. First used with SIMS and MALDI MS that operate under vacuum, interest has grown for mass spectrometry ionization sources that allow for effective imaging but where the analysis can be performed at ambient pressure with minimal or no sample preparation. We introduce here a versatile source for MALDESI imaging analysis coupled to a hybrid LTQ-FT-ICR mass spectrometer. The imaging source offers single shot or multi-shot capability per pixel with full control over the laser repetition rate and mass spectrometer scanning cycle. Scanning rates can be as fast as 1 pixel/second and a spatial resolution of 45 μm was achieved with oversampling.

  6. The comparison of naturally weathered oil and artificially photo-degraded oil at the molecular level by a combination of SARA fractionation and FT-ICR MS

    International Nuclear Information System (INIS)

    Highlights: • Weathered oils from the Hebei Spirit oil spill and photo degraded oils are compared. • We investigate changes of polar species at the molecular level by 15T FT-ICR MS. • Significant reduction of sulfur class compounds in saturates fraction is observed. • The relative abundance of protonated compounds (presumably basic nitrogen compounds) increase after degradation. • Changes of polar compounds occurred by natural and photo degradation are similar. -- Abstract: Two sets of oil samples, one obtained from different weathering stages of the M/V Hebei Spirit oil spill site and the other prepared by an in vitro photo-degradation experiment, were analyzed and compared at the molecular level by atmospheric pressure photo-ionization coupled with Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS). For a more detailed comparison at the molecular level, the oil samples were separated into saturate, aromatic, resin, and asphaltene (SARA) fractions before MS analysis. Gravimetric analysis of the SARA fractions revealed a decreased weight percentage of the aromatic fraction and an increased resin fraction in both sets of samples. Molecular-level investigations of the SARA fractions showed a significant reduction in the S1 class in the saturate fraction and increase of S1O1 class compounds with high DBE values in resin fraction. Levels of N1 and N1O1 class compounds resulting in protonated ions (presumably basic nitrogen compounds) increased after degradation compared to compounds generating molecular ions (presumably non-basic nitrogen compounds). This study revealed changes occurring in heteroatom polar species of crude oils such as sulfur and nitrogen containing compounds that have not been easily detected with conventional GC based techniques

  7. Broad-band hard X-ray reflectors

    DEFF Research Database (Denmark)

    Joensen, K.D.; Gorenstein, P.; Hoghoj, P.;

    1997-01-01

    Interest in optics for hard X-ray broad-band application is growing. In this paper, we compare the hard X-ray (20-100 keV) reflectivity obtained with an energy-dispersive reflectometer, of a standard commercial gold thin-film with that of a 600 bilayer W/Si X-ray supermirror. The reflectivity of ...

  8. Molecular-Scale Investigation with ESI-FT-ICR-MS on Fractionation of Dissolved Organic Matter Induced by Adsorption on Iron Oxyhydroxides.

    Science.gov (United States)

    Lv, Jitao; Zhang, Shuzhen; Wang, Songshan; Luo, Lei; Cao, Dong; Christie, Peter

    2016-03-01

    Adsorption by minerals is a common geochemical process of dissolved organic matter (DOM) which may induce fractionation of DOM at the mineral-water interface. Here, we examine the molecular fractionation of DOM induced by adsorption onto three common iron oxyhydroxides using electrospray ionization coupled with Fourier-transform ion cyclotron resonance mass spectrometry (ESI-FT-ICR-MS). Ferrihydrite exhibited higher affinity to DOM and induced more pronounced molecular fractionation of DOM than did goethite or lepidocrocite. High molecular weight (>500 Da) compounds and compounds high in unsaturation or rich in oxygen including polycyclic aromatics, polyphenols and carboxylic compounds had higher affinity to iron oxyhydroxides and especially to ferrihydrite. Low molecular weight compounds and compounds low in unsaturation or containing few oxygenated groups (mainly alcohols and ethers) were preferentially maintained in solution. This study confirms that the double bond equivalence and the number of oxygen atoms are valuable parameters indicating the selective fractionation of DOM at mineral and water interfaces. The results of this study provide important information for further understanding the behavior of DOM in the natural environment. PMID:26815589

  9. Chemical Composition and Potential Environmental Impacts of Water-Soluble Polar Crude Oil Components Inferred from ESI FT-ICR MS.

    Directory of Open Access Journals (Sweden)

    Yina Liu

    Full Text Available Polar petroleum components enter marine environments through oil spills and natural seepages each year. Lately, they are receiving increased attention due to their potential toxicity to marine organisms and persistence in the environment. We conducted a laboratory experiment and employed state-of-the-art Fourier-transform ion cyclotron resonance mass spectrometry (FT-ICR-MS to characterize the polar petroleum components within two operationally-defined seawater fractions: the water-soluble fraction (WSF, which includes only water-soluble molecules, and the water-accommodated fraction (WAF, which includes WSF and microscopic oil droplets. Our results show that compounds with higher heteroatom (N, S, O to carbon ratios (NSO:C than the parent oil were selectively partitioned into seawater in both fractions, reflecting the influence of polarity on aqueous solubility. WAF and WSF were compositionally distinct, with unique distributions of compounds across a range of hydrophobicity. These compositional differences will likely result in disparate impacts on environmental health and organismal toxicity, and thus highlight the need to distinguish between these often-interchangeable terminologies in toxicology studies. We use an empirical model to estimate hydrophobicity character for individual molecules within these complex mixtures and provide an estimate of the potential environmental impacts of different crude oil components.

  10. Characterizing the secondary organic aerosol products of ozone and α-pinene using ultrahigh-resolution FT-ICR mass spectrometry

    Science.gov (United States)

    Putman, A.; Offenberg, J. H.; Fisseha, R.; Kundu, S.; Rahn, T.; Mazzoleni, L. R.

    2011-12-01

    Three samples of secondary organic aerosol (SOA) were generated by reacting a-pinene and ozone in the presence of variable concentrations of hydroxyl radical scavenging cyclohexane and were characterized by ultrahigh-resolution Fourier transform ion cyclotron resonance mass spectrometry (FT ICR MS). The reactions were performed in the presence of different concentrations of hydroxyl radical scavenger. This provided an opportunity to examine the molecular level differences of SOA. More than 900 chemical formulas for negative ions were identified over the mass range of 100 to 820 u. The experimental reproducibility of the SOA composition and the technical reproducibility of the mass spectra were evaluated. Similar chemical formulas with similar relative abundances were observed in all three experiments. A few exceptions were particular high relative abundance signals such as m/z 357, 367 and 539, whose production efficiency increased in the presence of cyclohexane, and m/z 185, 199, 215, 231 and 261, whose production efficiency decreased in the presence of cyclohexane. In general, the composition of a-pinene SOA was only slightly influenced by the concentration of the hydroxyl radical scavenger, cyclohexane. The negative ion spectra of the SOA contained four groups of peaks over the following mass ranges: 150 aldol condensations or esterification reactions. To provide insight into the formation mechanisms, the molecular structures of selected group II compounds (300 < n < 475) were investigated using ultra-high resolution MS2.

  11. Analysis of impact of temperature and saltwater on Nannochloropsis salina bio-oil production by ultra high resolution APCI FT-ICR MS

    KAUST Repository

    Sanguineti, Michael Mario

    2015-05-01

    Concentrated Nannochloropsis salina paste was reconstituted in distilled water and synthetic saltwater and processed at 250°C and 300°C via hydrothermal liquefaction. The resulting bio-oils yielded a diverse distribution of product classes, as analyzed by ultra high resolution APCI FT-ICR MS. The organic fractions were analyzed and both higher temperatures and distilled water significantly increase the number of total compounds present and the number of product classes. Major bio-oil products consisted of N1O1, hydrocarbon, and O2 classes, while O1, O4, S1, N1O2, and N2O2 classes represented the more significant minor classes. Both chlorine and sulfur containing compounds were detected in both distilled and saltwater reactions, while fewer numbers of chlorine and sulfur containing products were present in the organic fraction of the saltwater reactions. Further refinement to remove the chlorine and sulfur contents appears necessary with marine microalgal bio-oils produced via hydrothermal liquefaction. The higher heating value (MJ/kg) as calculated by the Boie equation of classes of interest in the bio-oil reveals a significant potential of algal hydrothermal liquefaction products as a sustainable and renewable fuel feedstock. © 2015.

  12. Changes of Petroleum Acid Distribution Characterized by FT-ICR MS in Heavy Acidic Crude Oil after True Boiling Point Distillation

    Institute of Scientific and Technical Information of China (English)

    Liu Yingrong; Zhang Qundan; Wang Wei; Liu Zelong; Zhu Xinyi; Tian Songbai

    2014-01-01

    The molecular transformations of carboxylic acids in heavy acidic SL crude before and after true boiling point distillation were examined by ultra-high resolution negative-ion electrospray ionization (ESI) Fourier transform ion cyclo-tron resonance mass spectrometry (FT-ICR MS). The acid class (heteroatom number), type (z numbers) and carbon number distributions were positively characterized. It was found out that the total acid number (TAN) of SL crude decreased after true boiling point distillation, and the abundance of O2 class in mass spectra was also found to be reduced from 67.6%to 34.5%in SL TBP mixed crude as measured by MS spectra, indicating to a potential carboxylic acid decomposition. However, it was interesting that the carboxylic acids type distribution in both oils was almost the same although their relative abundance in SL TBP mixed crude turned to be much lower, suggesting that various petroleum carboxylic acid types have the similar thermal decomposition reaction behavior. Furthermore, for each O2 type of acids in SL TBP mixed crude, the abundance of carboxylic acids with carbon number higher than 35 was reduced greatly, especially for those with carbon number higher than 60, the mass peaks of which were nearly totally removed, indicating that the large carboxylic acid molecules in heavy fractions decomposed more signiifcantly because of longer heating time during the true boiling point distillation process. As a result, the reduction of TAN may be caused by the thermal decomposition of carboxylic acids especially those with high carbon number, suggesting that quick distillation or much lower pressure is required to avoid the thermal decomposition.

  13. Ultra-Broad-Band Optical Parametric Amplifier or Oscillator

    Science.gov (United States)

    Strekalov, Dmitry; Matsko, Andrey; Savchenkov, Anatolly; Maleki, Lute

    2009-01-01

    A concept for an ultra-broad-band optical parametric amplifier or oscillator has emerged as a by-product of a theoretical study in fundamental quantum optics. The study was originally intended to address the question of whether the two-photon temporal correlation function of light [in particular, light produced by spontaneous parametric down conversion (SPDC)] can be considerably narrower than the inverse of the spectral width (bandwidth) of the light. The answer to the question was found to be negative. More specifically, on the basis of the universal integral relations between the quantum two-photon temporal correlation and the classical spectrum of light, it was found that the lower limit of two-photon correlation time is set approximately by the inverse of the bandwidth. The mathematical solution for the minimum two-photon correlation time also provides the minimum relative frequency dispersion of the down-converted light components; in turn, the minimum relative frequency dispersion translates to the maximum bandwidth, which is important for the design of an ultra-broad-band optical parametric oscillator or amplifier. In the study, results of an analysis of the general integral relations were applied in the case of an optically nonlinear, frequency-dispersive crystal in which SPDC produces collinear photons. Equations were found for the crystal orientation and pump wavelength, specific for each parametric-down-converting crystal, that eliminate the relative frequency dispersion of collinear degenerate (equal-frequency) signal and idler components up to the fourth order in the frequency-detuning parameter

  14. 焦化蜡油中碱性氮化合物的ESI FT-ICR MS表征及其催化裂化反应特性%CHARACTERIZATION OF BASIC NITROGEN COMPOUNDS IN COKER GAS OIL BY ESI FT-ICR MS AND THEIR CATALYTIC CRACKING PERFORMANCE

    Institute of Scientific and Technical Information of China (English)

    陈小博; 沈本贤; 孙金鹏; 山红红

    2013-01-01

    利用盐酸-乙醇溶液对焦化蜡油(CGO)中的碱性氮化合物进行了萃取分离,采用电喷雾-傅里叶变换离子回旋共振质谱仪(ESI FT-ICR MS)对CGO及其盐酸抽提物中的碱性氮化合物进行了表征,并在小型提升管催化裂化实验装置上,考察了碱性氮化合物的催化裂化反应特性.结果表明:CGO中的碱性氮化合物以N1类化合物为主,主要是带烷基或环烷基侧链的喹啉类和苯并喹啉类衍生物;在催化裂化条件下,萃取出的碱性氮化合物仍具有一定的催化裂化性能,但转化率较低,主要发生烷基侧链、环烷基侧链以及联苯桥键的断裂反应,较高含量的碱性氮化合物和多环芳烃是导致其转化率低、产物分布差的关键因素.%The basic nitrogen compounds were extracted by hydrochloric acid and alcohol from CGO.Then the types and structures of basic nitrogen species in CGO and its hydrochloric extract were characterized by Electrospray Ionization (ESI) Fourier Transform Ion Cyclotron Resonance Mass Spectrometry (FT-ICR MS),and the catalytic cracking performance of the basic nitrogen compounds was studied.The data indicate that N1 type basic nitrogen compounds are dominant in CGO and these species are mainly derivatives of quinoline and benzoquinoline with alkyl and cycloalkyl chains.Under the conditions of FCC,the basic nitrogen compounds extracted from CGO still have certain catalytic cracking ability;however,the conversion is relatively low.The bond-breakages of alkyl side-chains,cycloalkyl side-chains and biphenyl bridge are the main reaction.High content of basic nitrogen compounds and polycyclic aromatic hydrocarbons are the key factors that lead to lower conversion and poorer products distribution.

  15. Broad-band study with Suzaku of the magnetar class

    CERN Document Server

    Enoto, Teruaki; Makishima, Kazuo; Rea, Nanda; Hurley, Kevein; Shibata, Shinpei

    2010-01-01

    Broad-band (0.8-70 keV) spectra of the persistent X-ray emission from 9 magnetars were obtained with Suzaku, including 3 objects in apparent outburst. The soft X-ray component was detected from all of them, with a typical blackbody temperature of kT ~ 0.5 keV, while the hard-tail component, dominating above ~10 keV, was detected at ~1 mCrab intensity from 7 of them. Therefore, the spectrum composed of a soft emission and a hard-tail component may be considered to be a common property of magnetars, both in their active and quiescent states. Wide-band spectral analyses revealed that the hard-tail component has a 1-60 keV flux, Fh, comparable to or even higher than that carried by the 1-60 keV soft component, Fs. The hardness ratio of these objects, defined as xi=Fh/Fs, was found to be tightly anti-correlated with their characteristic age tau as xi=(3.3+/-0.3)x(tau/1 kyr)^(-0.67+/-0.04) with a correlation coefficient of -0.989, over the range from xi~10 to xi~0.1. Magnetars in outburst states were found to lie o...

  16. Broad band spectroscopic ellipsometry for the characterization of photovoltaic materials

    Energy Technology Data Exchange (ETDEWEB)

    Abou-Elfotouh, F.A.; Horner, G.S.; Coutts, T.J.; Wanlass, M.W. (Solar Energy Research Inst., Golden, CO (USA))

    1991-05-01

    The availability of commercial spectroscopic ellipsometers (SE) has been restricted to the UV-visible range from 250-900 nm. Although this is useful for many applications, it must be extended to the near IR region (up to 1700 nm) for the study of the optical behavior of most photovoltaic materials. This paper discusses the development of a broad band (300-1700 nm) SE which has been used to measure the optical characteristics of various materials. Among these are the polycrystalline thin film materials, CuInSe{sub 2} and CdTe (for which single crystal samples have also been investigated), and materials for high efficiency cascade solar cells including InP, InGaAs and InGaAsP. Most of these data are not presently available over such a wide spectral range. Experimentally, a rotating polarizer-fixed analyzer ellipsometer with an a.c. detection system has been developed for accurate measurement of psi and {Delta}, the relevant ellipsometric parameters, in the near IR. This approach has certain advantages over the rotating analyzer-fixed polarizer systems including reduced sensitivity to room light. The analytical methods include the use of a specially developed computer modeling program which gives psi and {Delta} for a given set of values related to the film thickness (which may be finite or zero) and to the optical properties of the substrate. (orig.).

  17. A rapid and sensitive UHPLC-FT-ICR MS/MS method for identification of chemical constituents in Rhodiola crenulata extract, rat plasma and rat brain after oral administration.

    Science.gov (United States)

    Han, Fei; Li, Yanting; Ma, Li; Liu, Tianfeng; Wu, Yawen; Xu, Rui; Song, Aihua; Yin, Ran

    2016-11-01

    A rapid and sensitive UHPLC-FT-ICR MS/MS method was developed for the first time to analyze the extract of Rhodiola crenulata and the constituents absorbed into rat blood and brain after oral administration. Under the optimized conditions, a total of 64 chemical constituents were identified or tentatively characterized in vitro in 30min, and also 24 and 9 chemical constituents were detected in rat plasma and brain respectively, by comparing the retention time, accurate mass and/or MS/MS data of blank and dosed sample. The results indicated that the developed UHPLC-FT-ICR MS/MS method was suitable for detection and identifying the chemical constituents in Rhodiola crenulata extract, rat plasma and rat brain, and it could be used as a powerful and reliable analytical strategy for rapid identification of chemical constituents in vitro and in vivo for other traditional Chinese herbal medicines (TCMs). Furthermore, the detected chemical constituents in rat brain could be speculated to be the pharmacodynamic substances of Rhodiola crenulata for Alzheimer's disease (AD) and it could also provide useful chemical information for further mass spectrometry imaging and bioactive substances research on Rhodiola crenulata. PMID:27591603

  18. The characteristic of power flow in broad band dynamic vibration absorber

    Institute of Scientific and Technical Information of China (English)

    WANG Minqing; SHENG Meiping; SUN Jincai; LIU Yi

    2002-01-01

    DVA (dynamic vibration absorber) is good for restrain of the resonance vibration in low frequency, especially under the condition that there are only one mode or two modes in a frequency band. It seems rather difficult to control the resonance vibration of elastic structures in high frequency, since usually there are so many modes in high frequency band. The broad band DVA is brought forward to reduce the resonance vibration of elastic structures. The broad band DVA is designed on the basis of the characteristic of power flow in structure in this paper.The broad band DVA is effective on absorbing the resonance vibration power flow of the mostimportant modes. The ability of absorbing vibration for the broad band DVA is analyzed indetail. The results obtained in this paper provide a basis for the optimization design of thebroad band DVA and the optimization positions on structures.

  19. System Realization of Broad Band Digital Beam Forming for Digital Array Radar

    Directory of Open Access Journals (Sweden)

    Wang Feng

    2013-09-01

    Full Text Available Broad band Digital Beam Forming (DBF is the key technique for the realization of Digital Array Radar (DAR. We propose the method of combination realization of the channel equalization and DBF time delay filter function by using adaptive Sample Matrix Inversion algorithm. The broad band DBF function is realized on a new DBF module based on parallel fiber optic engines and Field Program Gate Array (FPGA. Good performance is achieved when it is used to some radar products.

  20. Estimating carbon dioxide fluxes from temperate mountain grasslands using broad-band vegetation indices

    Directory of Open Access Journals (Sweden)

    G. Wohlfahrt

    2010-02-01

    Full Text Available The broad-band normalised difference vegetation index (NDVI and the simple ratio (SR were calculated from measurements of reflectance of photosynthetically active and short-wave radiation at two temperate mountain grasslands in Austria and related to the net ecosystem CO2 exchange (NEE measured concurrently by means of the eddy covariance method. There was no significant statistical difference between the relationships of midday mean NEE with narrow- and broad-band NDVI and SR, measured during and calculated for that same time window, respectively. The skill of broad-band NDVI and SR in predicting CO2 fluxes was higher for metrics dominated by gross photosynthesis and lowest for ecosystem respiration, with NEE in between. A method based on a simple light response model whose parameters were parameterised based on broad-band NDVI allowed to improve predictions of daily NEE and is suggested to hold promise for filling gaps in the NEE time series. Relationships of CO2 flux metrics with broad-band NDVI and SR however generally differed between the two studied grassland sites indicting an influence of additional factors not yet accounted for.

  1. Broad-Band Spectral Indices Variability of BL Lacertae by Wavelet Method

    Indian Academy of Sciences (India)

    Hao-Jing Zhang; Jing-Ming Bai; Yu-Ying Bao; Xiong Zhang

    2014-09-01

    BL Lacertae is one of the famous AGN that shows convincing evidence to support periodic variability. We compile R-band data and radio 22 GHz database from the available literature to build the light curves and to calculate broad-band spectral indices. This paper employs the wavelet periodic estimation method. The analysis results indicate that the most possible period is 7.02–7.36 yr in the selected wave-bands. The broad-band spectral indices have a possible period of 4.11 yr as a half value in selected wave-bands. The results confirm that the variability period in the radio 22 GHz is in agreement with the optical R band of about 7.01 yr, as also mentioned in other literatures.

  2. Broad-Band Visually Evoked Potentials: Re(convolution in Brain-Computer Interfacing.

    Directory of Open Access Journals (Sweden)

    Jordy Thielen

    Full Text Available Brain-Computer Interfaces (BCIs allow users to control devices and communicate by using brain activity only. BCIs based on broad-band visual stimulation can outperform BCIs using other stimulation paradigms. Visual stimulation with pseudo-random bit-sequences evokes specific Broad-Band Visually Evoked Potentials (BBVEPs that can be reliably used in BCI for high-speed communication in speller applications. In this study, we report a novel paradigm for a BBVEP-based BCI that utilizes a generative framework to predict responses to broad-band stimulation sequences. In this study we designed a BBVEP-based BCI using modulated Gold codes to mark cells in a visual speller BCI. We defined a linear generative model that decomposes full responses into overlapping single-flash responses. These single-flash responses are used to predict responses to novel stimulation sequences, which in turn serve as templates for classification. The linear generative model explains on average 50% and up to 66% of the variance of responses to both seen and unseen sequences. In an online experiment, 12 participants tested a 6 × 6 matrix speller BCI. On average, an online accuracy of 86% was reached with trial lengths of 3.21 seconds. This corresponds to an Information Transfer Rate of 48 bits per minute (approximately 9 symbols per minute. This study indicates the potential to model and predict responses to broad-band stimulation. These predicted responses are proven to be well-suited as templates for a BBVEP-based BCI, thereby enabling communication and control by brain activity only.

  3. Broad Band Spectral Index TeV Blazars Detected by Fermi LAT

    Indian Academy of Sciences (India)

    Yong Juan Cha; Xiong Zhang

    2014-09-01

    We collected the radio, K-band, optical, X-ray, and -ray data for 35 TeV blazars detected by Fermi LAT and studied the possible correlation between different broad band spectral indices (r.o, r.x, ir.o, ir.x, o., x.) in all states (average/high/low). Based on our results, we suggested that the seed photons of the -ray drive from the synchrotron radiation themselves.

  4. Broad-band near-field ground motion simulations in 3-dimensional scattering media

    KAUST Repository

    Imperatori, W.

    2012-12-06

    The heterogeneous nature of Earth\\'s crust is manifested in the scattering of propagating seismic waves. In recent years, different techniques have been developed to include such phenomenon in broad-band ground-motion calculations, either considering scattering as a semi-stochastic or purely stochastic process. In this study, we simulate broad-band (0–10 Hz) ground motions with a 3-D finite-difference wave propagation solver using several 3-D media characterized by von Karman correlation functions with different correlation lengths and standard deviation values. Our goal is to investigate scattering characteristics and its influence on the seismic wavefield at short and intermediate distances from the source in terms of ground motion parameters. We also examine scattering phenomena, related to the loss of radiation pattern and the directivity breakdown. We first simulate broad-band ground motions for a point-source characterized by a classic ω2 spectrum model. Fault finiteness is then introduced by means of a Haskell-type source model presenting both subshear and super-shear rupture speed. Results indicate that scattering plays an important role in ground motion even at short distances from the source, where source effects are thought to be dominating. In particular, peak ground motion parameters can be affected even at relatively low frequencies, implying that earthquake ground-motion simulations should include scattering also for peak ground velocity (PGV) calculations. At the same time, we find a gradual loss of the source signature in the 2–5 Hz frequency range, together with a distortion of the Mach cones in case of super-shear rupture. For more complex source models and truly heterogeneous Earth, these effects may occur even at lower frequencies. Our simulations suggests that von Karman correlation functions with correlation length between several hundred metres and few kilometres, Hurst exponent around 0.3 and standard deviation in the 5–10 per cent

  5. Vacuum UV broad-band absorption spectroscopy: a powerful diagnostic tool for reactive plasma monitoring

    OpenAIRE

    Cunge, G; Fouchier, M; Brihoum, M; Bodart, P.; Touzeau, M.; N. Sadeghi

    2011-01-01

    Abstract Broad band UV-visible absorption spectroscopy is widely used to measure the concentration of radicals in reactive plasmas. We extended the applicability of this technique to the VUV (115 nm to 200 nm), the spectral range in which the electronic transitions from the ground state to the Rydberg or pre-dissociated states of many closed shell molecules are located. This gives access to the absolute densities of species which do not, or weakly absorb in the UV/visible range. The techni...

  6. Dual-etalon cavity ring-down frequency-comb spectroscopy with broad band light source

    Science.gov (United States)

    Chandler, David W; Strecker, Kevin E

    2014-04-01

    In an embodiment, a dual-etalon cavity-ring-down frequency-comb spectrometer system is described. A broad band light source is split into two beams. One beam travels through a first etalon and a sample under test, while the other beam travels through a second etalon, and the two beams are recombined onto a single detector. If the free spectral ranges ("FSR") of the two etalons are not identical, the interference pattern at the detector will consist of a series of beat frequencies. By monitoring these beat frequencies, optical frequencies where light is absorbed may be determined.

  7. Achievement of Narrow-Band CARS Signal by Manipulating Broad-band Laser Spectrum

    International Nuclear Information System (INIS)

    We theoretically demonstrate the achievement of narrow-band coherent anti-Stokes Raman scattering (CARS) signal by manipulating broad-band probe spectrum. The narrowing of the CARS signal depends on the spectrum bandwidth of the probe beam, and thus high-resolution CARS signal for a complicated quantum system can be obtained by the simple spectrum manipulation. Furthermore, the energy-level diagram for the complicated quantum system can also be labelled by measuring the CARS signal at a given frequency. (fundamental areas of phenomenology (including applications))

  8. A Soft X-ray Polarimeter Designed for Broad-band X-ray Telescopes

    OpenAIRE

    Marshall, Herman L.

    2007-01-01

    A novel approach for measuring linear X-ray polarization over a broad-band using conventional imaging optics and cameras is described. A new type of high efficiency grating, called the critical angle transmission grating is used to disperse soft X-rays radially from the telescope axis. A set of multilayer-coated paraboloids re-image the dispersed X-rays to rings in the focal plane. The intensity variation around these rings is measured to determine three Stokes parameters: I, Q, and U. By lat...

  9. THE BROAD-BAND CCD PHOTOMETRY AND DUST PRODUCTION RATES OF COMET HALE-BOPP

    Institute of Scientific and Technical Information of China (English)

    Huang Keliang; Hu Jingyao; Zhou Hongnan

    2000-01-01

    Based upon broad-band CCD observation data of comet Hale-Bopp obtained by a 60cm telescope at Xinglong Station of Beijing Astronomical Observatory during March-August, 1996, the photometric results of comet Hale-Bopp are reported. Using the photometric results, the dust production rate, radius and mass of nucleus of comet Hale-Bopp are estimated as follows: dM/dt~1.5×105 kgs-1, Rn~35.5km, and Mn~5.65×1016kg.

  10. The broad-band CCD photometry and dust production rates of comet Hale-Bopp

    Institute of Scientific and Technical Information of China (English)

    黄克谅; 胡景耀; 周洪楠

    2000-01-01

    Based upon broad-band CCD observation data of comet Hale-Bopp obtained by a 60 cm telescope at Xinglong Station of Beijing Astronomical Observatory during March-August, 1996, the photometric results of comet Hale-Bopp are reported. Using the photometric results, the dust production rate, radius and mass of nucleus of comet Hale-Bopp are estimated as follows: dM/df ~ 1.5 × 105 kgs-1, Rn~35.5 km, and Mn~5.65×1016 kg.

  11. The broad-band CCD photometry and dust production rates of comet Hale-Bopp

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    Based upon broad-band CCD observation data of comet Hale-Bopp obtained by a 60 cm telescope at Xinglong Station of Beijing Astronomical Observatory during March-August, 1996, the photometric results of comet Hale-Bopp are reported. Using the photometric results, the dust production rate, radius and mass of nucleus of comet Hale-Bopp are estimated as follows: dM/dt~1.5×105 kgs-1, Rn~35.5 km, and Mn~5.65×1016 kg.

  12. The diverse broad-band light-curves of Swift GRBs reproduced with the cannonball model

    CERN Document Server

    Dado, Shlomo; De Rújula, A

    2009-01-01

    Two radiation mechanisms, inverse Compton scattering (ICS) and synchrotron radiation (SR), suffice within the cannonball (CB) model of long gamma ray bursts (LGRBs) and X-ray flashes (XRFs) to provide a very simple and accurate description of their observed prompt emission and afterglows. Simple as they are, the two mechanisms and the burst environment generate the rich structure of the light curves at all frequencies and times. This is demonstrated for 33 selected Swift LGRBs and XRFs, which are well sampled from early time until late time and well represent the entire diversity of the broad band light curves of Swift LGRBs and XRFs. Their prompt gamma-ray and X-ray emission is dominated by ICS of glory light. During their fast decline phase, ICS is taken over by SR which dominates their broad band afterglow. The pulse shape and spectral evolution of the gamma-ray peaks and the early-time X-ray flares, and even the delayed optical `humps' in XRFs, are correctly predicted. The canonical and non-canonical X-ra...

  13. Suzaku broad band observations of the Seyfert 1 galaxies Mrk 509 and Mrk 841

    CERN Document Server

    Cerruti, M; Boisson, C; Costantini, E; Longinotti, A L; Matt, G; Mouchet, M; Petrucci, P O

    2011-01-01

    We report an analysis and modelling of new Suzaku observations of the Seyfert 1 galaxies Mrk509 and Mrk841, taken between April and November 2006, for Mrk509, and January and July 2007, for Mrk841, for a total exposure time of ~100 ks each. Data from XIS and HXD/PIN instruments, going from 0.5 to 60 keV, represent the best resolution simultaneous broad band X-ray spectrum for these objects. We fitted the broad band spectrum of both sources with a double Comptonisation model, adding a neutral reflection from distant material and a two-phase warm absorber. We then studied the two competitive models aimed to explain the soft excess with atomic processes: a blurred ionised disc reflection and an ionised absorption by a high velocity material. When fitting the data in the 3-10 keV range with a power law spectrum, and extrapolating this result to low energies, a soft excess is clearly observed below 2 keV: its strength is however weak compared to past observations of both sources. A moderate hard excess is seen at ...

  14. Estimate of the atmospheric turbidity from three broad-band solar radiation algorithms. A comparative study

    Directory of Open Access Journals (Sweden)

    G. López

    2004-09-01

    Full Text Available Atmospheric turbidity is an important parameter for assessing the air pollution in local areas, as well as being the main parameter controlling the attenuation of solar radiation reaching the Earth's surface under cloudless sky conditions. Among the different turbidity indices, the Ångström turbidity coefficient β is frequently used. In this work, we analyse the performance of three methods based on broad-band solar irradiance measurements in the estimation of β. The evaluation of the performance of the models was undertaken by graphical and statistical (root mean square errors and mean bias errors means. The data sets used in this study comprise measurements of broad-band solar irradiance obtained at eight radiometric stations and aerosol optical thickness measurements obtained at one co-located radiometric station. Since all three methods require estimates of precipitable water content, three common methods for calculating atmospheric precipitable water content from surface air temperature and relative humidity are evaluated. Results show that these methods exhibit significant differences for low values of precipitable water. The effect of these differences in precipitable water estimates on turbidity algorithms is discussed. Differences in hourly turbidity estimates are later examined. The effects of random errors in pyranometer measurements and cloud interferences on the performance of the models are also presented. Examination of the annual cycle of monthly mean values of β for each location has shown that all three turbidity algorithms are suitable for analysing long-term trends and seasonal patterns.

  15. Unveiling the broad band X-ray continuum and iron line complex in Mkr 841

    CERN Document Server

    Petrucci, P O; Matt, G; Longinotti, A L; Malzac, J; Mouchet, M; Boisson, C; Maraschi, L; Nandra, K; Ferrando, P

    2007-01-01

    Mkr 841 is a bright Seyfert 1 galaxy known to harbor a strong soft excess and a variable K$\\alpha$ iron line. It has been observed during 3 different periods by XMM for a total cumulated exposure time of $\\sim$108 ks. We present in this paper a broad band spectral analysis of the complete EPIC-pn data sets. We were able to test two different models for the soft excess, a relativistically blurred photoionized reflection (\\r model) and a relativistically smeared ionized absorption (\\a model). The continuum is modeled by a simple cut-off power law and we also add a neutral reflection. These observations reveal the extreme and puzzling spectral and temporal behaviors of the soft excess and iron line. The 0.5-3 keV soft X-ray flux decreases by a factor 3 between 2001 and 2005 and the line shape appears to be a mixture of broad and narrow components. We succeed in describing this complex broad-band 0.5-10 keV spectral variability using either \\r or \\a to fit the soft excess. Both models give statistically equivalen...

  16. A GaAs monolithic low-noise broad-band amplifier

    Science.gov (United States)

    Archer, J. A.; Weidlich, H. P.; Pettenpaul, E.; Petz, F. A.; Huber, J.

    1981-12-01

    This paper describes the design, fabrication, and performance of GaAs monolithic low-noise broad-band amplifiers intended for broadcast receiver antenna amplifier, IF amplifier, and instrumentation applications. The process technology includes the use of Czochralski-grown semiinsulating substrates, localized implantation of ohmic and FET channel regions, and silicon nitride for passivation and MIM capacitors. The amplifiers employ shunt feedback to obtain input matching and flat broad-band response. One amplifier provides a gain of 24 dB, bandwidth of 930 MHz, and noise figure of 5.0 dB. A second amplifier provides a gain of 17 dB, bandwidth of 1400 MHz, and noise figure of 5.6 dB. Input and output VSWR's are typically less than 2:1 and the third-order intercept points are 28 and 32 dB, respectively. Improved noise figure and intercept point can be achieved by the use of external RF chokes.

  17. 烃源岩生成有机酸过程的高分辨质谱研究%Characterizing thermal evolution of acid species in hydrocarbon source rock by using negative-ion ESI FT-ICR MS

    Institute of Scientific and Technical Information of China (English)

    蒋启贵; 刘鹏; 黎茂稳; 陶国亮

    2014-01-01

    研究石油中有机酸的生成过程对研究储层改造、石油润湿性及页岩油可动性评价具有重要意义。在热压生烃模拟实验基础上,对Ⅲ型烃源岩不同演化阶段生成油中的非烃馏分进行了负离子电喷雾傅立叶变换离子回旋共振质谱分析,研究了烃源岩生成有机酸过程。对样品生成有机酸分析表明,在整个演化过程烃源岩都能生成有机酸,在低演化阶段主要生成脂肪酸,随演化程度的升高,脂肪酸丰度快速减少,芳环酸开始大量生成。随演化程度的增加,芳环上短链取代基发生断裂,并促进了有机酸的缩合,使得生成的有机酸缩合度逐渐提高,高碳数有机酸逐渐减少;烃源岩生成脂肪酸系列中存在偶奇优势,生成的C16、C18脂肪酸存在异常高丰度, C16、C18脂肪酸异常丰度现象可能是污染造成的,是否与烃源岩类型及成熟度有关尚需进一步研究。%The study on the generation process of organic acid species in hydrocarbon source rocks is of a great significance for understanding reservoir alteration, oil wettability, and shale oil removability evaluation. Based on the thermocompression simulation experiment of hydrocarbon generation, the polar species of the expelled oils from a source rock (Type Ⅲ kerogen) at different maturity stages were determined by negative-ion electrospray ionization (ESI) Fourier Transform Ion Cyclotron Mass Spectrometry (ESI FT-ICR MS). The result shows that the organic acid species can be generated during the whole thermal evolution of hydrocarbon source rock. At low maturity levels (early oil window), fatty acids (DBE=1) are the most abundant species. With the increasing maturity, naphthenic acids and aromatic acids become dominant species. At higher maturity levels, most of the acidic species have been thermally cracked and aromatized, thus only the O2 class with short chains and high DBE values (aromatic acids

  18. Broad-band analysis of the spectral evolution of GX 339-4

    Science.gov (United States)

    Clavel, M.; Rodriguez, J.; Corbel, S.

    2015-07-01

    Black Hole X-ray binaries display large outbursts during which their spectral properties are strongly variable. Their high-energy emission includes the contribution of thermal and non-thermal components that are respectively attributed to the emission of an accretion disk and the one of a jet. How these structures form and evolve over time is still under investigation. The aim of our group is to provide the most up to date generic properties of these objects, as observed along the course of their outbursts, in order to constrain the theoretical models. Therefore, I will present the systematic broad-band analysis of the spectral properties of black hole binaries that we are currently developing, using the 2010 outburst of GX 339-4 as an example. I will give an overview of the results we obtained using observations at all wavelengths from proprietary radio data to hard X-rays.

  19. Broad-band time-resolved near infrared spectroscopy in the TJ-II stellarator

    Energy Technology Data Exchange (ETDEWEB)

    Rodriguez, M.C.; Pastor, I.; Cal, E. de la; McCarthy, K.J. [Laboratorio Nacional de Fusion, CIEMAT, Madrid (Spain); Diaz, D. [Universidad Autonoma de Madrid, Dept Quimica Fisica Aplicada, Madrid (Spain)

    2014-11-15

    First experimental results on broad-band, time-resolved Near Infrared (NIR;here loosely defined as covering from 750 to 1650 nm) passive spectroscopy using a high sensitivity InGaAs detector are reported for the TJ-II Stellarator. Experimental set-up is described together with its main characteristics, the most remarkable ones being its enhanced NIR response, broadband spectrum acquisition in a single shot, and time-resolved measurements with up to 1.8 kHz spectral rate. Prospects for future work and more extended physics studies in this newly open spectral region in TJ-II are discussed. (copyright 2014 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim) (orig.)

  20. Mapping the Broad-band Spectrum of a New Candidate Intermediate Mass Black Hole

    Science.gov (United States)

    Farrell, Sean

    2014-10-01

    We request joint XMM-Newton & HST observations of a new intermediate mass black hole candidate in the galaxy LEDA 87326 to map the broad-band spectral energy distribution from X-ray to near-IR. Previous observations with the XMM-Newton EPIC and OM cameras detected an X-ray source with an observed 0.2-10 keV luminosity of 6E41 erg/s, with the X-ray spectrum dominated by a hard power law and the UV/optical data consistent with thermal emission from a cool (~0.08 keV) accretion disc. The high X-ray luminosity and low disc temperature imply a black hole mass > 4000 Msun. By observing this source simultaneously with XMM-Newton and the HST we will confirm that the observed optical emission is from an accretion disc and determine whether any reprocessing in the outer disc is present.

  1. Broad-band Circularly Polarized Patch Antenna for Multi-Mode Navigation Application

    Directory of Open Access Journals (Sweden)

    Wangencheng

    2012-11-01

    Full Text Available A broad-band circularly polarizedpatch antenna is developed for GPS/ GLONASS/ BEIDOU/ GALILEO systems. The antenna includes four L-probes, a circular patch with four edges trimming and a feed network. The four L-probes are excited by a feed network in equal magnitude and successive 90 phase difference. The edge cutting method is used to improve the axial ratio, impedance bandwidth and reduced the size of the antenna. The measured gains at 1227 and 1575 MHz are about 8 and 10 dB respectively. The 10 dB return loss bandwidth of the antenna is 42.9% from 1.1 to 1.7 GHz; the 3 dB axial ratio bandwidth of the antenna is 30% from 1.19 to 1.61 GHz. Low multipath effects have been observed of the antenna.

  2. Laser induced broad band anti-Stokes white emission from LiYbF4 nanocrystals

    Institute of Scientific and Technical Information of China (English)

    L. Marciniak; R. Tomala; M. Stefanski; D. Hreniak; W. Strek

    2016-01-01

    Spectroscopic properties of tetragonal LiYbF4 nanocrystals under high dense NIR excitation at vacuum condition were in-vestigated. White, broad band emission covering whole visible part of the spectrum from LiYbF4 nanocrystals was observed. Its in-tensity strongly depended on the excitation power, excitation wavelength and ambient pressure. Temperature of the nanocrystals un-der 975 nm excitation was determined as a function of excitation power. Strong photo-induced current was observed from LiYbF4 pallet. The emission kinetic was analyzed. The mechanism of the anti-Stokes white emission was discussed in terms of the la-ser-induced charge transfer emission from Yb2+ states.

  3. Characteristics of spatial modulation in nonlinear propagation of broad-band lasers stacked by chirped pulses

    International Nuclear Information System (INIS)

    To identify the potential risks of spatial modulation of broad-band laser beams stacked by chirped pulses on the safety of optics, this paper numerically investigated the effect of temporal modulation on the generation and growth of spatial modulation during its nonlinear propagation. When there is no additional spatial modulation and the B integral is limited in the practical working range(usually less than 2.0 rad), no spatial modulation will be generated for both normal dispersion and anomalous dispersion;while with the B integral further increasing, spatial modulation will emerge with a rapid growth. When there is additional spatial modulation for anomalous dispersion, the spatial modulation with additional temporal modulation will grow more quickly than that without additional temporal modulation. However, for normal dispersion,the growth of spatial modulation for both cases is similar. (authors)

  4. The range of validity of cluster masses and ages derived from broad-band photometry

    CERN Document Server

    Apellániz, J Maíz

    2009-01-01

    I analyze the stochastic effects introduced by the sampling of the stellar initial mass function (SIMF) in the derivation of the individual masses and the cluster mass function (CMF) from broad-band visible-NIR unresolved photometry. The classical method of using unweighted UBV photometry to simultaneously establish ages and extinctions of stellar clusters is found to be unreliable for clusters older than approx. 30 Ma, even for relatively large cluster masses. On the other hand, augmenting the filter set to include longer-wavelength filters and using weights for each filter increases the range of masses and ages that can be accurately measured with unresolved photometry. Nevertheless, a relatively large range of masses and ages is found to be dominated by SIMF sampling effects that render the observed masses useless, even when using UBVRIJHK photometry.

  5. The broad-band X-ray spectrum of Cygnus X-2

    Science.gov (United States)

    Pravdo, S. H.

    1983-01-01

    Cygnus X-2 was observed with the broad-band X-ray spectroscopy experiment, HEAO 1 A-2, in the energy range 0.4-18 keV for four intervals of approximately 31 s over the course of 5 days in 1977. The spectra can be adequately represented by single-temperature thermal bremmstrahlung continua with temperatures ranging from 3.7 x 10 to the 7th K to 6.4 x 10 to the 7th K. An examination of the spectra and the spectra-luminosity relationship effectively rules out one degenerate dwarf model for the X-ray emission. The far-UV continuum emission could be dominated by this continuum component during X-ray high states, an effect which would be detected in optical UV line observations. A Comptonized X-ray cloud around a neutron star remains a viable model for the observed X-ray spectra.

  6. A Soft X-ray Polarimeter Designed for Broad-band X-ray Telescopes

    CERN Document Server

    Marshall, Herman L

    2007-01-01

    A novel approach for measuring linear X-ray polarization over a broad-band using conventional imaging optics and cameras is described. A new type of high efficiency grating, called the critical angle transmission grating is used to disperse soft X-rays radially from the telescope axis. A set of multilayer-coated paraboloids re-image the dispersed X-rays to rings in the focal plane. The intensity variation around these rings is measured to determine three Stokes parameters: I, Q, and U. By laterally grading the multilayer optics and matching the dispersion of the gratings, one may take advantage of high multilayer reflectivities and achieve modulation factors over 50% over the entire 0.2 to 0.8 keV band. A sample design is shown that could be used with the Constellation-X optics.

  7. Higher degree moment tensor inversion of Mani earthquake using far-field broad- band recording

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    Breakthrough point source model, extended earthquake source model is used to calculate more seismic source parameters in this paper. We express seismic source using higher degree moment tensors, to reduce a large number terms originally presenting in higher degree moment tensor representation, Haskell rupture model is used. We inverted the source parameters of Mani earthquake in Tibet using broad-band body wave of 32 stations of Global Seismograph Network (GSN), the results show that it is a strike-slip fault, rupture direction is 75° , rupture duration is 19 s, the fault plan is f =77° , d =88° , l =0° , the auxiliary plane is f =347° , d =90° , l =178° , and the fault dimension is 47 km′ 28 km. These results will give new quantitative data for earth dynamics and have practical meaning for seismic source tomography research.

  8. Cerebral oxygenation monitoring during cardiac bypass surgery in infants with broad band spatially resolved spectroscopy

    Science.gov (United States)

    Soschinski, Jan; Ben Mine, Lofti; Geraskin, Dmitri; Bennink, Gerardus; Kohl-Bareis, Matthias

    2007-07-01

    Neurological impairments following cardio-pulmonary bypass (CPB) during open heart surgery can result from microembolism and ischaemia. Here we present results from monitoring cerebral haemodynamics during CPB with near infrared spatially resolved broadband spectroscopy. In particular, the study has the objective (a) to monitor oxy- and deoxy-hemoglobin concentrations (oxy-Hb, deoxy-Hb) and their changes as well as oxygen saturation during CPB surgery and (b) to develop and test algorithms for the calculation of these parameters from broad band spectroscopy. For this purpose a detection system was developed based on an especially designed lens imaging spectrograph with optimised sensitivity of recorded reflectance spectra for wavelengths between 600 and 1000 nm. The high f/#-number of 1:1.2 of the system results in about a factor of 10 higher light throughput combined with a lower astigmatism and crosstalk between channels when compared with a commercial mirror spectrometers (f/# = 1:4). For both hemispheres two independent channels each with three source-detector distances (ρ = 25 . 35 mm) were used resulting in six spectra. The broad band approach allows to investigate the influence of the wavelength range on the calculated haemoglobin concentrations and their changes and oxygen saturation when the attenuation A(λ) and its slope ΔA(λ)/Δρ are evaluated. Furthermore, the different depth sensitivities of these measurement parameters are estimated from Monte Carlo simulations and exploited for an optimization of the cerebral signals. It is demonstrated that the system does record cerebral oxygenation parameters during CPB in infants. In particular, the correlation of haemoglobin concentrations with blood supply (flow, pressure) by the heart-lung machine and the significant decreases in oxygen saturation during cardiac arrest is discussed.

  9. Broad band seismology in the Scotia region. The base Esperanza seismological observatory

    International Nuclear Information System (INIS)

    The lithospheric study and the identification of relevant lateral heterogeneities in the Antarctic continent and borderlands, is essential to understand the geodynamic evolution both of the continental and oceanic bordering regions. The complexity of the geological evolution and the structural properties of the lithosphere in the Scotia area have been stressed by many authors. The present setting of the area is the result of the mutual interaction among the Antarctic, South American and several minor plants whose geodynamic history and actual boundaries are still partially unknown. The intense seismic activity that characterizes the region encourages the use of the seismological approach to investigate the lithospheric structure of the area. Since January 1992 a broad band three components station is operating at the Antarctic base Esperanza in the NE area of Antarctic Peninsula. The station has been installed with financial support of the Italian Programma Nazionale di Ricerche in Antartide (PNRA) by Osservatorio Geofisico Sperimentale (OGS) and Instituto Antartico Argentino (IAA). Russi et al. (1994) have analyzed selected recordings using the frequency-time analysis (FTAN) method obtaining some relevant information on the large scale structure of the lithosphere in the Scotia region even if data recorded by a single station were available. The extension of our analysis to further events and to horizontal component records is here presented. Within the framework of the international co-operation to the Antarctic Seismographic Network, the OGS and the IAA are upgrading the Esperanza station and installing an additional broad band station near the town of Ushuaia (Tierra del Fuego, Argentina) with the financial support of PNRA. The inversion of the dispersion curves through the FTAN of the signals recorded by an increased number of stations and generated by events with source-station paths spanning the region will allow us to extract the elastic and anelastic

  10. Study of LEO-SAT microwave link for broad-band mobile satellite communication system

    Science.gov (United States)

    Fujise, Masayuki; Chujo, Wataru; Chiba, Isamu; Furuhama, Yoji; Kawabata, Kazuaki; Konishi, Yoshihiko

    1993-01-01

    In the field of mobile satellite communications, a system based on low-earth-orbit satellites (LEO-SAT's) such as the Iridium system has been proposed. The LEO-SAT system is able to offer mobile telecommunication services in high-latitude areas. Rain degradation, fading and shadowing are also expected to be decreased when the system is operated at a high elevation angle. Furthermore, the propagation delay generated in the LEO-SAT system is less pronounced than that in the geostationary orbit satellite (GEO-SAT) system and, in voice services, the effect of the delay is almost negligible. We proposed a concept of a broad-band mobile satellite communication system with LEO-SAT's and Optical ISL. In that system, a fixed L-band (1.6/1.5 GHz) multibeam is used to offer narrow band service to the mobile terminals in the entire area covered by a LEO-SAT and steerable Ka-band (30/20 GHz) spot beams are used for the wide band service. In this paper, we present results of a study of LEO-SAT microwave link between a satellite and a mobile terminal for a broad-band mobile satellite communication system. First, the results of link budget calculations are presented and the antennas mounted on satellites are shown. For a future mobile antenna technology, we also show digital beamforming (DBF) techniques. DBF, together with modulation and/or demodulation, is becoming a key technique for mobile antennas with advanced functions such as antenna pattern calibration, correction, and radio interference suppression. In this paper, efficient DBF techniques for transmitting and receiving are presented. Furthermore, an adaptive array antenna system suitable for this LEO-SAT is presented.

  11. [Optimization of broad-band flat-field holographic concave grating without astigmatism].

    Science.gov (United States)

    Kong, Peng; Tang, Yu-guo; Bayanheshig; Li, Wen-hao; Cui, Jin-jiang

    2012-02-01

    The desirable imaging locations of the flat-field holographic concave gratings should be in a plane. And the object can be imaged perfectly by the grating when the tangential focal curve and sagittal focal curve both superpose the intersection of the image plane and dispersion plane. But actually, the defocus can not be eliminated over the entire wavelength range, while the astigmatism vanishes when the grating parameters satisfy some conditions. An optimization method for broad-band flat-field holographic concave gratings with absolute astigmatism correction was proposed. The ray tracing software ZEMAX was used for investigating the imaging properties of the grating. And we made a comparison between spectral performance of gratings designed by this new method and that by conventional method, respectively. The results indicated that the spectral performance of gratings designed by using the absolute astigmatism correction method can be as good as gratings designed with the conventional method. And the focusing performance in the sagittal direction is much better, so that the S/N ratio can be greatly improved.

  12. High sensitivity ultra-broad-band absorption spectroscopy of inductively coupled chlorine plasma

    Science.gov (United States)

    Marinov, Daniil; Foucher, Mickaël; Campbell, Ewen; Brouard, Mark; Chabert, Pascal; Booth, Jean-Paul

    2016-06-01

    We propose a method to measure the densities of vibrationally excited Cl2(v) molecules in levels up to v  =  3 in pure chlorine inductively coupled plasmas (ICPs). The absorption continuum of Cl2 in the 250-450 nm spectral range is deconvoluted into the individual components originating from the different vibrational levels of the ground state, using a set of ab initio absorption cross sections. It is shown that gas heating at constant pressure is the major depletion mechanism of the Cl2 feedstock in the plasma. In these line-integrated absorption measurements, the absorption by the hot (and therefore rarefied) Cl2 gas in the reactor centre is masked by the cooler (and therefore denser) Cl2 near the walls. These radial gradients in temperature and density make it difficult to assess the degree of vibrational excitation in the centre of the reactor. The observed line-averaged vibrational distributions, when analyzed taking into account the radial temperature gradient, suggest that vibrational and translational degrees of freedom in the plasma are close to local equilibrium. This can be explained by efficient vibrational-translational (VT) relaxation between Cl2 and Cl atoms. Besides the Cl2(v) absorption band, a weak continuum absorption is observed at shorter wavelengths, and is attributed to photodetachment of Cl- negative ions. Thus, line-integrated densities of negative ions in chlorine plasmas can be directly measured using broad-band absorption spectroscopy.

  13. Attenuation structure beneath the volcanic front in northeastern Japan from broad-band seismograms

    Science.gov (United States)

    Takanami, Tetsuo; Selwyn Sacks, I.; Hasegawa, Akira

    2000-10-01

    Anelastic structure in the asthenosphere beneath the volcanic front in northeastern Japan arc is estimated by using the spectral amplitude ratio data of P and S waves from about 100 events which occurred in the subducting Pacific slab below Japan. These earthquakes occurred within a 90 km radius centered about the station Sawauchi (SWU), with focal depths ranging from 60 to 200 km. Waveforms were recorded by the Carnegie broad-band three-component seismograph and were corrected for instrument responses, crustal reverberations, corner frequencies, and superimposed noise. Ray paths and travel times of P and S waves are calculated using a three-dimensional velocity model [Zhao, D., Hasegawa, A., Horiuchi, S., 1992. J. Geophys. Res. 97, 19909-19928]. We find a low- Q region ( QS˜70) extending down to 55 km depth from the lower crust beneath the volcanic front. Using Q-temperature laboratory results [Sato, H., Sacks, I.S., Murase, T., Muncill, G., Fukushima, H., 1989. J. Geophys. Res. 94, 10647-10661], this implies a temperature of about 130°C higher than the eastern forearc region and about 30°C higher than the western backarc region, in good agreement with the tomographic results of Zhao et al. [Zhao, D., Hasegawa, A., Horiuchi, S., 1992. J. Geophys. Res. 97, 19909-19928]. This suggests that low velocities in the crust and uppermost mantle beneath SWU may be explained by a subsolidus temperature increase without partial melting.

  14. The impact of JWST broad-band filter choice on photometric redshift estimation

    CERN Document Server

    Bisigello, L; Colina, L; Fèvre, O Le; Nørgaard-Nielsen, H U; Pérez-González, P G; Pye, J; van der Werf, P; Ilbert, O; Grogin, N; Koekemoer, A

    2016-01-01

    The determination of galaxy redshifts in James Webb Space Telescope (JWST)'s blank-field surveys will mostly rely on photometric estimates, based on the data provided by JWST's Near-Infrared Camera (NIRCam) at 0.6-5.0 {\\mu}m and Mid Infrared Instrument (MIRI) at {\\lambda}>5.0 {\\mu}m. In this work we analyse the impact of choosing different combinations of NIRCam and MIRI broad-band filters (F070W to F770W), as well as having ancillary data at {\\lambda}=10, but the zphot quality significantly degrades at S/N<=5. Adding MIRI photometry with one magnitude brighter depth than the NIRCam depth allows for a redshift recovery of 83-99%, depending on SED type, and its effect is particularly noteworthy for galaxies with nebular emission. The vast majority of NIRCam galaxies with [F150W]=29 AB mag at z=7-10 will be detected with MIRI at [F560W, F770W]<28 mag if these sources are at least mildly evolved or have spectra with emission lines boosting the mid-infrared fluxes.

  15. Recovering galaxy stellar population properties from broad-band spectral energy distribution fitting

    CERN Document Server

    Pforr, Janine; Tonini, Chiara

    2012-01-01

    We explore the dependence of galaxy stellar population properties derived from broad-band SED-fitting - such as age, stellar mass, dust reddening, etc. - on a variety of parameters, such as SFHs, metallicity, IMF, dust reddening and reddening law, and wavelength coverage. Mock galaxies serve as test particles. We confirm our earlier results based on real z=2 galaxies, that usually adopted \\tau-models lead to overestimate the SFR and to underestimate the stellar mass. Here, we show that - for star-forming galaxies - ages, masses and reddening, can be well determined simultaneously only when the correct SFH is identified. This is the case for inverted-\\tau-models at high-z, for which we find that the mass recovery (at fixed IMF) is as good as ~0.04 dex. Since the right SFH is usually unknown we quantify offsets generated by adopting standard fitting setups. Stellar masses are generally underestimated resulting from underestimating ages. For fitting setups with a variety of SFHs the median mass recovery at z ~ 2...

  16. The solar wind control of Jupiter's broad-band kilometric radio emission

    Science.gov (United States)

    Barrow, C. H.; Leblanc, Y.; Desch, M. D.

    1988-01-01

    Observations of the solar wind close to Jupiter are compared with the broad-band kilometric radio emission (bKOM), using data recorded by Voyager 1 and Voyager 2 during 1979. The lower bKOM frequencies, less than about 300 kHz, are found to correlate with the solar wind density and pressure and with the interplanetary magnetic field (IMF) magnitude during periods when there is a well-defined magnetic sector structure. The results suggest that lower frequency bKOM events are most likely to occur after a sector boundary has passed Jupiter during the period when the solar wind density and the IMF magnitude are increasing towards the sector center. The average bKOM energy per Jovian rotation tends to have lower values soon after the sector center has passed. Higher-frequency/higher-energy bKOM emission may be contaminated by hectometric emission (HOM) and differently correlated with solar activity. The solar wind control may also be obscured by some stronger control. It is suggested that electron density fluctuations in the Io torus, where the source is believed to be located, may be responsible for variations in the beaming and hence variations in the observed emission.

  17. Broad band X-ray spectrum of KS 1947+300 with BeppoSAX

    CERN Document Server

    Naik, S; Dotani, T; Paul, B

    2006-01-01

    We present results obtained from three BeppoSAX observations of the accretion-powered transient X-ray pulsar KS 1947+300 carried out during the declining phase of its 2000 November -- 2001 June outburst. A detailed spectral study of KS 1947+300 across a wide X-ray band (0.1--100.0 keV) is attempted for the first time here. Timing analysis of the data clearly shows a 18.7 s pulsation in the X-ray light curves in the above energy band. The pulse profile of KS 1947+300 is characterized by a broad peak with sharp rise followed by a narrow dip. The dip in the pulse profile shows a very strong energy dependence. Broad-band pulse-phase-averaged spectroscopy obtained with three of the BeppoSAX instruments shows that the energy spectrum in the 0.1--100 keV energy band has three components, a Comptonized component, a ~0.6 keV blackbody component, and a narrow and weak iron emission line at 6.7 keV with a low column density of material in the line of sight. We place an upper limit on the equivalent width of the iron K_\\...

  18. Toward broad-band x-ray detected ferromagnetic resonance in longitudinal geometry

    International Nuclear Information System (INIS)

    An ultrahigh-vacuum-compatible setup for broad-band X-ray detected ferromagnetic resonance (XFMR) in longitudinal geometry is introduced which relies on a low-power, continuous-wave excitation of the ferromagnetic sample. A simultaneous detection of the conventional ferromagnetic resonance via measuring the reflected microwave power and the XFMR signal of the X-ray absorption is possible. First experiments on the Fe and Co L3-edges of a permalloy film covered with Co nanostripes as well as the Fe and Ni K-edges of a permalloy film are presented and discussed. Two different XFMR signals are found, one of which is independent of the photon energy and therefore does not provide element-selective information. The other much weaker signal is element-selective, and the dynamic magnetic properties could be detected for Fe and Co separately. The dependence of the latter XFMR signal on the photon helicity of the synchrotron light is found to be distinct from the usual x-ray magnetic circular dichroism effect

  19. Broad band turbulent spectra in gamma-ray burst light curves

    CERN Document Server

    van Putten, Maurice H P M; Frontera, Filippo

    2014-01-01

    Broad band power density spectra offer a window to understanding turbulent behavior in the emission mechanism and, at the highest frequencies, in the putative inner engines powering long GRBs. We describe a chirp search method which steps aside Fourier analysis for signal detection in the Poisson noise-dominated 2 kHz sampled BeppoSAX light curves. An efficient numerical implementation is described in $O(Nn\\log n)$ operations, where $N$ is the number of chirp templates and $n$ is the length of the light curve time series, suited for embarrassingly parallel processing. For detection of individual chirps of duration $\\tau=1$ s, the method is one order of magnitude more sensitive in SNR than Fourier analysis. The Fourier-chirp spectra of GRB 010408 and GRB 970816 show a continuation of the spectral slope up to 1 kHz of turbulence identified in low frequency Fourier analysis. The same continuation is observed in an ensemble averaged spectrum of 40 bright long GRBs. An outlook on a similar analysis of upcoming gra...

  20. Ultra-Broad Band Radar Cross Section Reduction of Waveguide Slot Antenna with Metamaterials

    Directory of Open Access Journals (Sweden)

    Qiang Fu

    2016-06-01

    Full Text Available To reduce the radar cross section of a waveguide slot antenna, a three-layer metamaterial is presented based on orthogonal double split-ring resonators. The absorption characteristics of three-layer metamaterial are demonstrated by simulation. Moreover, the metamaterials have been loaded on common waveguide slot antenna according to the surface current distribution. The ultra-broad band radar cross section reduction of the antenna with metamaterials had been theoretically and experimentally investigated by radiating and scattering performances. Experimental and simulated results showed that the proposed antenna with metamaterials performed broadband radar cross section reduction from 3.9 GHz to 18 GHz and the gain had been improved due to the coupling effect between slot and the period structure. The maximal radar cross section reduction achieved 17.81 dB at 8.68 GHz for x-polarized incidence and 21.79 dB at 6.25 GHz for y-polarized waves.

  1. A broad band x-ray imaging spectrophotometer to observe SN1987A

    International Nuclear Information System (INIS)

    This paper reports on a broad band x-ray imaging spectrophotometer (BBXRIS), to be flown as a sounding rocket payload in late 1987. It has been built to make high spatial and spectral resolution observations of SN1987A. The focal plane instrument, an imaging gas scintillation proportional counter, offers energy resolution of 8% (FWHM) at 6 keV, and is sensitive to x-rays from 0.1 to 20.0 keV. Soft x-rays (0.1--1.8 keV) are imaged by a nested pair of Wolter Type I grazing incidence mirrors with a resolution of 8 arcmin, a field of view of 2.6 degrees, and an effective area of 70 cm2 at 0.2 keV. A specially designed collimator is able to resolve SN1987A from LMC X-1 and provide approximately 70 cm2 of effective area from 0.1--20.0 keV

  2. The puzzling case of GRB 990123: prompt emission and broad-band afterglow modeling

    CERN Document Server

    Corsi, A; Kuulkers, E; Amati, L; Antonelli, L A; Costa, E; Feroci, M; Frontera, F; Guidorzi, C; Heise, J; Zand, J; Maiorano, E; Montanari, E; Nicastro, L; Pian, E; Soffitta, P

    2005-01-01

    We report on BeppoSAX simultaneous X- and gamma-ray observations of the bright GRB 990123. We present the broad-band spectrum of the prompt emission, including optical, X- and gamma-rays, confirming the suggestion that the emission mechanisms at low and high frequencies must have different physical origins. In the framework of the standard fireball model, we discuss the X-ray afterglow observed by the NFIs and its hard X-ray emission up to 60 keV several hours after the burst, detected for about 20 ks by the PDS. Considering the 2-10 keV and optical light curves, the 0.1-60 keV spectrum during the 20 ks in which the PDS signal was present and the 8.46 GHz upper limits, we find that the multi-wavelength observations cannot be readily accommodated by basic afterglow models. While the temporal and spectral behavior of the optical afterglow is possibly explained by a synchrotron cooling frequency between the optical and the X-ray energy band during the NFIs observations, in X-rays this assumption only accounts fo...

  3. BROAD-BAND AND WIDE DYNAMIC-RANGE SEISMIC OBSERVATIONS WITH AN STS-SEISMOGRAPH AT SYOWA STATION, EAST ANTARCTICA

    OpenAIRE

    カナオ, マサキ; カミヌマ, カツタダ; Masaki, KANAO; Katsutada, Kaminuma

    1994-01-01

    Broad-band and wide dynamic-range seismic observations with a three-component Streckeisen seismometer (STS-1V, -1H) have been carried out at Syowa Station, East Antarctica since April 1989. A digital acquisition system for broad-band (BRB) velocity signals was started from May 1990,for the purpose of providing valuable data for the study of global seismology. In this paper, the seismic observations with STS are presented during the winter period of the 33rd Japanese Antarctic Research Expedit...

  4. Model atmospheres broad-band colors, bolometric corrections and temperature calibrations for O - M stars

    Science.gov (United States)

    Bessell, M. S.; Castelli, F.; Plez, B.

    1998-05-01

    Broad band colors and bolometric corrections in the Johnson-Cousins-Glass system (Bessell, 1990; Bessell & Brett, 1988) have been computed from synthetic spectra from new model atmospheres of Kurucz (1995a), Castelli (1997), Plez, Brett & Nordlund (1992), Plez (1995-97), and Brett (1995a,b). These atmospheres are representative of larger grids that are currently being completed. We discuss differences between the different grids and compare theoretical color-temperature relations and the fundamental color temperature relations derived from: (a) the infrared-flux method (IRFM) for A-K stars (Blackwell & Lynas-Gray 1994; Alonso et al. 1996) and M dwarfs (Tsuji et al. 1996a); (b) lunar occultations (Ridgway et al. 1980) and (c) Michelson interferometry (Di Benedetto & Rabbia 1987; Dyck et al. 1996; Perrin et al. 1997) for K-M giants, and (d) eclipsing binaries for M dwarfs. We also compare color - color relations and color - bolometric correction relations and find good agreement except for a few colors. The more realistic fluxes and spectra of the new model grids should enable accurate population synthesis models to be derived and permit the ready calibration of non-standard photometric passbands. As well, the theoretical bolometric corrections and temperature - color relations will permit reliable transformation from observed color magnitude diagrams to theoretical HR diagrams. Tables 1-6 are only available in electronic form at the CDS via anonymous ftp to cdsarc.u-strasbg.fr (130.79.128.5) or via http://cdsweb.u-strasbg.fr/Abstract.html

  5. Properties of Broad Band Continuum of Narrow Line Seyfert 1 Galaxies

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    We have performed a statistical study of the properties of the broadband continuum of Narrow Line Seyfert 1 galaxies (NLS1s) by collecting ratio,infrared, optical and X-ray continuum data from various databases and comparedthe results with control samples of Broad Line Seyfert 1 galaxies (BLSls). We findthat the fraction (~ 6%) of Radio Loud (RL) NLSls is significantly less than thatof BLS1s (~ 13%), which is caused by the lack of radio-very-loud sources in theformer. The rarity of RL NLS1s, especially radio-very-loud ones, is consistent withthe scenario of small black hole and high accretion rate for NLSls. Six new radio loudNLSls are found and five RL NLS1 candidates are presented. In comparison withthe BLS1s, the NLS1s tend to have stronger far infrared emission, cooler infraredcolors and redder B- K color, which suggests that NLS1s are hosted by dust-richernuclei. The NLS1s also show steeper soft X-ray spectrum and large soft X-rayto optical flux ratio, while a significant fraction show fiat soft X-ray spectra. Atleast two factors can account for this, absorption and spectral variability. We alsoperform a correlation analysis between various broad band data. It is found thatmost correlations identified for NLS1s are also valid for radio quiet BLS1s: (1) theoptical colors are anti-correlated with X-ray spectral index; (2) higher optical, X-ray and NIR luminosity objects show bluer optical colors and red H - K color; (3)higher luminosity objects show warmer IRAS color; (4) the radio loudness correlateswith B - K and X-ray to optical flux ratio. Radio loud objects behave somewhatdifferently in a few correlations.

  6. Multiwavelength observations of the energetic GRB 080810: detailed mapping of the broad-band spectral evolution

    Science.gov (United States)

    Page, K. L.; Willingale, R.; Bissaldi, E.; Postigo, A. De Ugarte; Holland, S. T.; McBreen, S.; O'Brien, P. T.; Osborne, J. P.; Prochaska, J. X.; Rol, E.; Rykoff, E. S.; Starling, R. L. C.; Tanvir, N. R.; van der Horst, A. J.; Wiersema, K.; Zhang, B.; Aceituno, F. J.; Akerlof, C.; Beardmore, A. P.; Briggs, M. S.; Burrows, D. N.; Castro-Tirado, A. J.; Connaughton, V.; Evans, P. A.; Fynbo, J. P. U.; Gehrels, N.; Guidorzi, C.; Howard, A. W.; Kennea, J. A.; Kouveliotou, C.; Pagani, C.; Preece, R.; Perley, D.; Steele, I. A.; Yuan, F.

    2009-11-01

    GRB 080810 was one of the first bursts to trigger both Swift and the Fermi Gamma-ray Space Telescope. It was subsequently monitored over the X-ray and UV/optical bands by Swift, in the optical by Robotic Optical Transient Search Experiment (ROTSE) and a host of other telescopes, and was detected in the radio by the Very Large Array. The redshift of z = 3.355 +/- 0.005 was determined by Keck/High Resolution Echelle Spectrometer (HIRES) and confirmed by RTT150 and NOT. The prompt gamma/X-ray emission, detected over 0.3-103 keV, systematically softens over time, with Epeak moving from ~600 keV at the start to ~40 keV around 100s after the trigger; alternatively, this spectral evolution could be identified with the blackbody temperature of a quasi-thermal model shifting from ~60 to ~3keV over the same time interval. The first optical detection was made at 38s, but the smooth, featureless profile of the full optical coverage implies that this is originated from the afterglow component, not from the pulsed/flaring prompt emission. Broad-band optical and X-ray coverage of the afterglow at the start of the final X-ray decay (~8ks) reveals a spectral break between the optical and X-ray bands in the range of 1015-2 × 1016Hz. The decay profiles of the X-ray and optical bands show that this break initially migrates blueward to this frequency and then subsequently drifts redward to below the optical band by ~3 × 105s. GRB 080810 was very energetic, with an isotropic energy output for the prompt component of 3 × 1053 and 1.6 × 1052 erg for the afterglow; there is no evidence for a jet break in the afterglow up to 6d following the burst. This paper is dedicated to the memory of Professor Martin Turner, who sadly passed away during its writing. Martin was an influential figure in X-ray Astronomy and an excellent PhD supervisor. He will be greatly missed. E-mail: kpa@star.le.ac.uk ‡ NASA postdoctoral program fellow.

  7. Enlarged broad band photodetection using Indium doped TiO{sub 2} alloy thin film

    Energy Technology Data Exchange (ETDEWEB)

    Sarkar, Mitra Barun [National Institute of Technology Agartala, Department of Electronics and Communication Engineering, Jirania, Tripura (West) 799055 (India); Mondal, Aniruddha, E-mail: aniruddhamo@gmail.com [National Institute of Technology Agartala, Department of Electronics and Communication Engineering, Jirania, Tripura (West) 799055 (India); Choudhuri, Bijit; Mahajan, Bikram Kishore; Chakrabartty, Shubhro [National Institute of Technology Agartala, Department of Electronics and Communication Engineering, Jirania, Tripura (West) 799055 (India); Ngangbam, Chitralekha [National Institute of Technology Manipur, Department of Electronics and Communication Engineering, Takyelpat, Imphal, Manipur 795001 (India)

    2014-12-05

    Highlights: • An easy technique has been used to dope Indium (instantaneous source) into TiO{sub 2} TF. • An inhomogeneous layer of In{sub x}Ti{sub y}O{sub 2} alloy was formed due to doping. • The lattice constant and optical band gap of TiO{sub 2} has increased after In doping. • Enhanced visible light absorption and detection were recorded for In doped TiO{sub 2} TF. • Almost no delay in photo response for In doped photodetector was observed. - Abstract: An instantaneous source of Indium (In) was used to dope the TiO{sub 2} thin film (TF) on the Si substrate. The X-ray diffraction depicted the presence of rutile phases of TiO{sub 2}, which shifted to the lower value 61.7 from 61.9 (2θ). Secondary ion mass spectrometry (SIMS) reveals that the diffusion of Indium ion yield decreases sharply from the surface, as approached toward the TiO{sub 2} TF–Si substrate interface. The bulk diffusion of In into TiO{sub 2} was observed at a depth of 125–200 nm, up to the edge of TiO{sub 2} TF. An inhomogeneous layer of In{sub x}Ti{sub y}O{sub 2} alloy was formed during annealing process. An average of two fold enhanced photo absorption was recorded for the In doped TiO{sub 2} TF in the 300–350 nm and 450–800 nm regions respectively. The main band gap of In doped TiO{sub 2} was increased to 3.4 eV, whereas the large absorption edge was observed at 3.1 eV. The leakage current (34 nA at −0.5 V) of In doped TiO{sub 2} TF detector was significantly reduced. A maximum 2.5 times (−3.5 V) enlarged photodetection has been observed for In doped TiO{sub 2} TF device under white light illumination. The In doped TiO{sub 2} TF detector shows the broad band photodetection, with an infinitesimal delay in its photo response time as compared to undoped TiO{sub 2} TF.

  8. Broad-band spectrophotometry of HAT-P-32 b: Search for a scattering signature in the planetary spectrum

    CERN Document Server

    Mallonn, M; Herrero, E; Hoyer, S; Kirk, J; Wheatley, P J; Seeliger, M; Mackebrandt, F; von Essen, C; Strassmeier, K G; Granzer, T; Künstler, A; Dhillon, V S; Marsh, T R; Gaitan, J

    2016-01-01

    Multi-colour broad-band transit observations offer the opportunity to characterise the atmosphere of an extrasolar planet with small- to medium-sized telescopes. One of the most favourable targets is the hot Jupiter HAT-P-32 b. We combined 21 new transit observations of this planet with 36 previously published light curves for a homogeneous analysis of the broad-band transmission spectrum from the Sloan u' band to the Sloan z' band. Our results rule out cloud-free planetary atmosphere models of solar metallicity. Furthermore, a discrepancy at reddest wavelengths to previously published results makes a recent tentative detection of a scattering feature less likely. Instead, the available spectral measurements of HAT-P-32 b favour a completely flat spectrum from the near-UV to the near-IR. A plausible interpretation is a thick cloud cover at high altitudes.

  9. Coherent-subspace array processing based on wavelet covariance: an application to broad-band, seismo-volcanic signals

    Science.gov (United States)

    Saccorotti, G.; Nisii, V.; Del Pezzo, E.

    2008-07-01

    Long-Period (LP) and Very-Long-Period (VLP) signals are the most characteristic seismic signature of volcano dynamics, and provide important information about the physical processes occurring in magmatic and hydrothermal systems. These events are usually characterized by sharp spectral peaks, which may span several frequency decades, by emergent onsets, and by a lack of clear S-wave arrivals. These two latter features make both signal detection and location a challenging task. In this paper, we propose a processing procedure based on Continuous Wavelet Transform of multichannel, broad-band data to simultaneously solve the signal detection and location problems. Our method consists of two steps. First, we apply a frequency-dependent threshold to the estimates of the array-averaged WCO in order to locate the time-frequency regions spanned by coherent arrivals. For these data, we then use the time-series of the complex wavelet coefficients for deriving the elements of the spatial Cross-Spectral Matrix. From the eigenstructure of this matrix, we eventually estimate the kinematic signals' parameters using the MUltiple SIgnal Characterization (MUSIC) algorithm. The whole procedure greatly facilitates the detection and location of weak, broad-band signals, in turn avoiding the time-frequency resolution trade-off and frequency leakage effects which affect conventional covariance estimates based upon Windowed Fourier Transform. The method is applied to explosion signals recorded at Stromboli volcano by either a short-period, small aperture antenna, or a large-aperture, broad-band network. The LP (0.2 2s) of the explosion recordings from the broad-band network. Source locations obtained this way are fully compatible with those retrieved from application of more traditional (and computationally expensive) time-domain techniques, such as the Radial Semblance method.

  10. Preliminary measurements of gamma ray effects on characteristics of broad-band GaAs field-effect transistor preamplifiers

    International Nuclear Information System (INIS)

    The effect of gamma radiation on electrical characteristics of cryogenically cooled broad-band low-noise microwave preamplifiers has been preliminarily evaluated. The change in the gain and noise figure of a 1-2 GHz preamplifier using GaAs microwave transistors was determined at gamma doses between 105 rad to 5 /times/ 108 rad. The gain and noise figure was measured at ambient temperatures of 300 K and 80 K. 8 refs., 2 figs

  11. Broad-band modelling of short gamma-ray bursts with energy injection from magnetar spin-down and its implications for radio detectability

    NARCIS (Netherlands)

    B.P. Gompertz; A.J. van der Horst; P.T. O'Brien; G.A. Wynn; K. Wiersema

    2015-01-01

    The magnetar model has been proposed to explain the apparent energy injection in the X-ray light curves of short gamma-ray bursts (SGRBs), but its implications across the full broad-band spectrum are not well explored. We investigate the broad-band modelling of four SGRBs with evidence for energy in

  12. A tunable dual-broad-band branch-line coupler utilizing composite right/left-handed transmission lines

    Institute of Scientific and Technical Information of China (English)

    ZHANG Yu; HU Li; HE Sai-ling

    2005-01-01

    A tunable dual-broad-band branch-line coupler (BLC) utilizing composite right/left-handed (CRLH) transmission lines is presented. Two λ/4 segments consisting of CRLH transmission lines are added to each port to broaden the dual bands of the branch-line coupler. Numerical simulation and optimal design of the novel coupler are presented. The dual bands of the novel coupler are tunable and broad. The 1-dB bandwidth of each passband is more than 16% of the central frequency.

  13. TRIGA-TRAP: A Penning trap setup for mass measurements on exotic and heavy nuclides

    International Nuclear Information System (INIS)

    The research reactor Triga Mainz offers unique possibilities for on-line mass measurements on neutron-rich isotopes as produced by fission of U-235, Pu-239 or Cf-249 targets. In addition, off-line measurements of actinide elements up to Cf-252 are planned. To this end a new Penning trap mass spectrometer will be installed at Triga Mainz, featuring not only the commonly used time-of-flight resonance technique, but also the non-destructive narrow-band image current technique, enabling the detection of a single singly-charged ion stored in the trap. Triga-Trap is the first on-line mass spectrometer for singly-charged heavy ions using this image current detection technique in combination with cryogenic Penning traps. In case of many heavy and superheavy nuclides, the production rates are often less than a few ions per second, but some isotopes exhibit comparably long half-lives in the order of seconds, which allows for repeated measurement cycles on the same trap content. Measurements with the newly developed narrow-band FT-ICR system at Triga-Trap will also serve as tests for future experiments at SHIPTRAP at GSI or MATS at FAIR

  14. Active Noise Control for Narrow-band and Broad-band Signals Using Q-Learning Technique

    Directory of Open Access Journals (Sweden)

    B. Raeisy

    2013-06-01

    Full Text Available The acoustic noise pollution is one of the serious disasters in the current industrialized life. Though traditional solutions based on noise absorption have many different applications, but these methods have low performance for low frequency noises. Active Noise Control (ANC has been introduced to resolve this problem. In this paper, a new active method is introduced for suppressing acoustic noises based on the reinforcement learning. To achieve this, an algorithm to control periodic noises is suggested. Then, the method is developed further to deal with multi-tonal signals with a large number of harmonics. At the next step, the broad-band signals are considered. The problem is broken into some sub-problems in frequency domain and each is solved via a reinforcement learning approach. In all of the proposed techniques no model for the environment is needed. Combining the reinforcement learning and the traditional methods in ANC for broad-band signals is a new line research considered here. This combination could increase the speed of the response, but some information of the dynamics of the environment is needed. This will cause the system to become compatible with gradual changes of the environment. Simulation results show the effectiveness of the proposed approach.

  15. A flexible experimental setup for femtosecond time-resolved broad-band ellipsometry and magneto-optics

    Energy Technology Data Exchange (ETDEWEB)

    Boschini, F.; Hedayat, H.; Piovera, C.; Dallera, C. [Dipartimento di Fisica, Politecnico di Milano, p.zza Leonardo da Vinci 32, 20133 Milano (Italy); Gupta, A. [Department of Chemistry, University of Alabama, Tuscaloosa, Alabama 35487 (United States); Carpene, E., E-mail: ettore.carpene@polimi.it [CNR-IFN, Dipartimento di Fisica, Politecnico di Milano, p.zza Leonardo da Vinci 32, 20133 Milano (Italy)

    2015-01-15

    A versatile experimental setup for femtosecond time-resolved ellipsometry and magneto-optical Kerr effect measurements in the visible light range is described. The apparatus is based on the pump-probe technique and combines a broad-band probing beam with an intense near-infrared pump. According to Fresnel scattering matrix formalism, the analysis of the reflected beam at different polarization states of the incident probe light allows one to determine the diagonal and the off-diagonal elements of the dielectric tensor in the investigated sample. Moreover, the pump-probe method permits to study the dynamics of the dielectric response after a short and intense optical excitation. The performance of the experimental apparatus is tested on CrO{sub 2} single crystals as a benchmark.

  16. Swiss AlpArray: deployment of the Swiss AlpArray temporary broad-band stations and their noise characterization

    Science.gov (United States)

    Molinari, Irene; Kissling, Edi; Clinton, John; Hetényi, György; Šipka, Vesna; Stipćević, Josip; Dasović, Iva; Solarino, Stefano; Wéber, Zoltán; Gráczer, Zoltán; Electronics Lab, SED

    2016-04-01

    One of the main actions of the AlpArray European initiative is the deployment of a dense seismic broad-band network, that complements the existing permanent stations. This will ensure a spatially homogeneous seismic coverage of the greater Alpine area for at least two years, allowing a great number of innovative scientific works to be carried out. Our contribution to the AlpArray Seismic Network consists in the deployment of 24 temporary broad-band stations: three in Switzerland, twelve in Italy, three in Croatia, three in Bosnia and Herzegovina and three in Hungary. This deployment is lead by ETH Zurich and founded by the Swiss-AlpArray Sinergia programme by SNSF, and is the result of a fruitful collaboration between five research institutes. Stations were installed between Autumn and Winter 2015. Our installations are both free field and in-house and consist of 21 STS-2 and 3 Trillium Compact sensors equipped with Taurus digitizers and 3G telemetry sending data in real time to the ETH EIDA node. In this work, we present sites and stations setting and we discuss in details the characteristics in terms of site effects and noise level of each station. In particular we analyse the power spectral density estimates investigating the major source of noise and the background noise related to seasons, time of the day, human activities and type of installation. In addition we will show examples of data usage - i.e. earthquake locations, noise cross correlations, measures of surface wave dispersion curves. We thanks the Swiss AlpArray Field Team: Blanchard A., Erlanger E. D., Jarić D., Herak D., M. Herak, Hermann M., Koelemeijer P. J., Markušić S., Obermann A., Sager K., Šikman S., Singer J., Winterberg S. SED Electronic Lab: Barman S., Graf P., Hansemann R., Haslinger F., Hiemer S., Racine R., Tanner R., Weber F.

  17. Broad-band spectral energy distribution of 3000 Å break quasars from the Sloan Digital Sky Survey

    Science.gov (United States)

    Meusinger, H.; Schalldach, P.; Mirhosseini, A.; Pertermann, F.

    2016-03-01

    Context. In past decades, huge surveys have confirmed the existence of populations of exotic and hitherto unknown quasar types. The discovery and investigation of these rare peculiar objects is important because they may represent links to special evolutionary stages and hold clues to the evolution of quasars and galaxies. Aims: The Sloan Digital Sky Survey (SDSS) discovered the unusual quasars J010540.75-003313.9 and J220445.27+003141.8 and a small number of similar objects. Their spectra are characterised by a break in the continuum around 3000 Å that neither shows the typical structure of broad absorption line (BAL) troughs nor is explained by typical intrinsic dust reddening. The main aim of the present paper was twofold. First, a new target-oriented search was performed in the spectra database of the SDSS to construct a sizable sample of such 3000 Å break quasars. Second, their broad-band spectral energy distribution (SED) was compared with SEDs of BAL quasars. Methods: We used the method of Kohonen self-organising maps for data mining in the SDSS spectra archive to search for more quasars with properties comparable to the prototypes J010540.75-003313.9 and J220445.27+003141.8. We constructed a sample of 3000 Å break quasars and comparison samples of quasars with similar properties, to some extent, but also showing indications for typical BAL features. Particular attention was payed to a possible contamination by rare stellar spectral types, in particular DQ white dwarfs. We construct ensemble-averaged broad-band SEDs based on archival data from SDSS, GALEX, 2MASS, UKIDSS, WISE, and other surveys. The SEDs were corrected for dust absorption at the systemic redshifts of the quasars by the comparison with the average SED of normal quasars. Results: We compiled a list of 23 quasars classified as 3000 Å break quasars with properties similar to 010540.75-003313.9 and J220445.27+003141.8. Their de-reddened arithmetic median composite SED is indistinguishable

  18. The Seismic Broad Band Western Mediterranean (wm) Network and the Obs Fomar Pool: Current state and Obs activities.

    Science.gov (United States)

    Pazos, Antonio; Davila, Jose Martin; Buforn, Elisa; Bezzeghoud, Mourad; Harnafi, Mimoun; Mattesini, Mauricio; Caldeira, Bento; Hanka, Winfried; El Moudnib, Lahcen; Strollo, Angelo; Roca, Antoni; Lopez de Mesa, Mireya; Dahm, Torsten; Cabieces, Roberto

    2016-04-01

    The Western Mediterranean (WM) seismic network started in 1996 as an initiative of the Royal Spanish Navy Observatory (ROA) and the Universidad Complutense de Madrid (UCM), with the collaboration of the GeoForschungsZentrum (GFZ) of Potsdam. A first broad band seismic station (SFUC) was installed close to Cádiz (South Spain). Since then, additional stations have been installed in the Ibero-Moghrebian region. In 2005, the "WM" code was assigned by the FDSN and new partners were jointed: Evora University (UEVO, Portugal), the Scientifique Institute of Rabat (ISRABAT, Morocco), and GFZ. Now days, the WM network is composed by 15 BB stations, all of them with Streckaisen STS-2 or STS-2.5 sensors, Quanterra or Earthdata digitizers and SeiscomP. Most them have co-installed a permanent geodetic GPS stations, and some them also have an accelerometer. There are 10 stations deployed in Spanish territory (5 in the Iberian peninsula, 1 in Balearic islands and 4 in North Africa Spanish places) with VSAT or Internet communications, 2 in Portugal (one of them without real time), and 3 in Morocco (2 VSAT and 1 ADSL). Additionally, 2 more stations (one in South Spain and one in Morocco) will be installed along this year. Additionally ROA has deployed a permanent real time VBB (CMG-3T: 360s) station at the Alboran Island. Due to the fact that part of the seismic activity is located at marine areas, and also because of the poor geographic azimuthal coverage at some zones provided by the land stations (specially in the SW of the San Vicente Cape area), ROA and UCM have acquired six broad band "LOBSTERN" OBS, manufactured by KUM (Kiel, Germany), conforming the OBS FOMAR pool. Three of them with CMG-40T sensor and the other with Trillium 120. These OBS were deployed along the Gibraltar strait since January to November 2014 to study the microseismicity in the Gibraltar strait area. In September 2015 FOMAR network has been deployed in SW of the San Vicente Cape for 8 months as a part of

  19. Broad-band spectral energy distribution of 3000 Angstroem break quasars from the Sloan Digital Sky Survey

    CERN Document Server

    Meusinger, H; Mirhosseini, A; Pertermann, F

    2016-01-01

    The Sloan Digital Sky Survey (SDSS) discovered a few unusual quasars with a characteristic break in the continuum around 3000 A that neither shows the typical structure of broad absorption line (BAL) troughs nor is explained by typical intrinsic dust reddening. We used the method of Kohonen self-organising maps for a systematical search for quasars with such properties in the SDSS spectra archive. We constructed a sample of 23 quasars classified as 3000 A break quasars and two comparison samples of quasars with similar properties, to some extent, but also showing typical BAL features. We computed ensemble-averaged broad-band SEDs based on archival data from SDSS, GALEX, 2MASS, UKIDSS, and WISE. The SEDs were corrected for intrinsic dust absorption by the comparison with the average SED of normal quasars. The de-reddened arithmetic median composite SED of the 3000 A break quasars is found to be indistinguishable from that of the unusual BAL quasars. We conclude that 3000 A break quasars are most likely extreme...

  20. Performance of the NIST goniocolorimeter with a broad-band source and multichannel charged coupled device based spectrometer

    Science.gov (United States)

    Podobedov, V. B.; Miller, C. C.; Nadal, M. E.

    2012-09-01

    The authors describe the NIST high-efficiency instrument for measurements of bidirectional reflectance distribution function of colored materials, including gonioapparent materials such as metallic and pearlescent coatings. The five-axis goniospectrometer measures the spectral reflectance of samples over a wide range of illumination and viewing angles. The implementation of a broad-band source and a multichannel CCD spectrometer corrected for stray light significantly increased the efficiency of the goniometer. In the extended range of 380 nm to 1050 nm, a reduction of measurement time from a few hours to a few minutes was obtained. Shorter measurement time reduces the load on the precise mechanical assembly ensuring high angular accuracy over time. We describe the application of matrix-based correction of stray light and the extension of effective dynamic range of measured fluxes to the values of 106 to 107 needed for the absolute characterization of samples. The measurement uncertainty was determined to be 0.7% (k = 2), which is comparable with similar instruments operating in a single channel configuration. Several examples of reflectance data obtained with the improved instrument indicate a 0.3% agreement compared to data collected with the single channel configuration.

  1. Broad-band Observations and Modeling of the Shell-Type Supernova Remnant G347.3-0.5

    CERN Document Server

    Ellison, D C; Gaensler, B M; Ellison, Donald C.; Slane, Patrick; Gaensler, Bryan M.

    2001-01-01

    The supernova remnant G347.3--0.5 emits a featureless power-law in X-rays, thought to indicate shock-acceleration of electrons to high energies. We here produce a broad-band spectrum of the bright NW limb of this source by combining radio observations from the Australia Telescope Compact Array (ATCA), X-ray observations from the Advanced Satellite for Cosmology and Astrophysics (ASCA), and TeV gamma-ray observations from the CANGAROO imaging Cerenkov telescope. We assume this emission is produced by an electron population generated by diffusive shock acceleration at the remnant forward shock. The nonlinear aspects of the particle acceleration force a connection between the widely different wavelength bands and between the electrons and the unseen ions, presumably accelerated simultaneously with the electrons. This allows us to infer the relativistic proton spectrum and estimate ambient parameters such as the supernova explosion energy, magnetic field, matter density in the emission region, and efficiency of t...

  2. Recovering galaxy stellar population properties from broad-band spectral energy distribution fitting II. The case with unknown redshift

    CERN Document Server

    Pforr, Janine; Tonini, Chiara

    2013-01-01

    (Abridged) In a recent work we explored the dependence of galaxy stellar population properties derived from broad-band spectral energy distribution fitting on the fitting parameters, e.g. SFHs, age grid, metallicity, IMF, dust reddening, reddening law, filter setup and wavelength coverage. In this paper we consider also redshift as a free parameter in the fit and study whether one can obtain reasonable estimates of photometric redshifts and stellar population properties at once. We use mock star-forming as well as passive galaxies placed at various redshifts (0.5 to 3) as test particles. Mock star-forming galaxies are extracted from a semi-analytical galaxy formation model. We show that for high-z star-forming galaxies photometric redshifts, stellar masses and reddening can be determined simultaneously when using a broad wavelength coverage and a wide template setup in the fit. Masses are similarly well recovered (median ~ 0.2 dex) as at fixed redshift. For old galaxies with little recent star formation masse...

  3. Broad-band transmission spectrum and K-band thermal emission of WASP-43b as observed from the ground

    CERN Document Server

    Chen, Guo; Wang, Hongchi; Nikolov, Nikolay; Fortney, Jonathan J; Seemann, Ulf; Wang, Wei; Mancini, Luigi; Henning, Thomas

    2014-01-01

    (Abridged) We observed one transit and one occultation of the hot Jupiter WASP-43b simultaneously in the g'r'i'z'JHK bands using the GROND instrument on the MPG/ESO 2.2-meter telescope. From the transit event, we have independently derived WASP-43's system parameters with high precision, and improved the period to be 0.81347437(13) days. No significant variation in transit depths is detected, with the largest deviations coming from the i', H, and K bands. Given the observational uncertainties, the broad-band transmission spectrum can be explained by either a flat featureless straight line that indicates thick clouds, synthetic spectra with absorption signatures of atomic Na/K or molecular TiO/VO that indicate cloud-free atmosphere, or a Rayleigh scattering profile that indicates high-altitude hazes. From the occultation event, we have detected planetary dayside thermal emission in the K-band with a flux ratio of 0.197 +/- 0.042%, which confirms previous detections obtained in the 2.09 micron narrow band and K...

  4. Multi-cavity coupling acoustic metamaterials with low-frequency broad band gaps based on negative mass density

    Science.gov (United States)

    Yang, Chuanhui; Wu, Jiu Hui; Cao, Songhua; Jing, Li

    2016-08-01

    This paper studies a novel kind of low-frequency broadband acoustic metamaterials with small size based on the mechanisms of negative mass density and multi-cavity coupling. The structure consists of a closed resonant cavity and an open resonant cavity, which can be equivalent to a homogeneous medium with effective negative mass density in a certain frequency range by using the parameter inversion method. The negative mass density makes the anti-resonance area increased, which results in broadened band gaps greatly. Owing to the multi-cavity coupling mechanism, the local resonances of the lower frequency mainly occur in the closed cavity, while the local resonances of the higher frequency mainly in the open cavity. Upon the interaction between the negative mass density and the multi-cavity coupling, there exists two broad band gaps in the range of 0-1800 Hz, i.e. the first-order band gap from 195 Hz to 660 Hz with the bandwidth of 465 Hz and the second-order band gap from 1157 Hz to 1663 Hz with the bandwidth of 506 Hz. The acoustic metamaterials with small size presented in this paper could provide a new approach to reduce the low-frequency broadband noises.

  5. Spectral modification of the laser emission of a terahertz quantum cascade laser induced by broad-band double pulse injection seeding

    Energy Technology Data Exchange (ETDEWEB)

    Markmann, Sergej, E-mail: sergej.markmann@ruhr-uni-bochum.de; Nong, Hanond, E-mail: nong.hanond@ruhr-uni-bochum.de; Hekmat, Negar; Jukam, Nathan [AG Terahertz Spektroskopie und Technologie, Ruhr-Universität Bochum, D-44780 Bochum (Germany); Pal, Shovon [AG Terahertz Spektroskopie und Technologie, Ruhr-Universität Bochum, D-44780 Bochum (Germany); Lehrstuhl für Angewandte Festkörperphysik, Ruhr-Universität Bochum, D-44780 Bochum (Germany); Scholz, Sven; Kukharchyk, Nadezhda; Ludwig, Arne; Wieck, Andreas D. [Lehrstuhl für Angewandte Festkörperphysik, Ruhr-Universität Bochum, D-44780 Bochum (Germany); Dhillon, Sukhdeep; Tignon, Jérôme [Laboratoire Pierre Aigrain, Ecole Normale Supérieure, UMR 8551 CNRS, UPMC, Univ. Paris 6, 75005 Paris (France); Marcadet, Xavier [Alcatel-Thales III-V Lab, Route Départementale 128, 91767 Palaiseau Cedex (France); Bock, Claudia; Kunze, Ulrich [Lehrstuhl für Werkstoffe und Nanoelektronik, Ruhr-Universität Bochum, D-44780 Bochum (Germany)

    2015-09-14

    We demonstrate by injection seeding that the spectral emission of a terahertz (THz) quantum cascade laser (QCL) can be modified with broad-band THz pulses whose bandwidths are greater than the QCL bandwidth. Two broad-band THz pulses delayed in time imprint a modulation on the single THz pulse spectrum. The resulting spectrum is used to injection seed the THz QCL. By varying the time delay between the THz pulses, the amplitude distribution of the QCL longitudinal modes is modified. By applying this approach, the QCL emission is reversibly switched from multi-mode to single mode emission.

  6. Synchronous chaos and broad band gamma rhythm in a minimal multi-layer model of primary visual cortex.

    Science.gov (United States)

    Battaglia, Demian; Hansel, David

    2011-10-01

    Visually induced neuronal activity in V1 displays a marked gamma-band component which is modulated by stimulus properties. It has been argued that synchronized oscillations contribute to these gamma-band activity. However, analysis of Local Field Potentials (LFPs) across different experiments reveals considerable diversity in the degree of oscillatory behavior of this induced activity. Contrast-dependent power enhancements can indeed occur over a broad band in the gamma frequency range and spectral peaks may not arise at all. Furthermore, even when oscillations are observed, they undergo temporal decorrelation over very few cycles. This is not easily accounted for in previous network modeling of gamma oscillations. We argue here that interactions between cortical layers can be responsible for this fast decorrelation. We study a model of a V1 hypercolumn, embedding a simplified description of the multi-layered structure of the cortex. When the stimulus contrast is low, the induced activity is only weakly synchronous and the network resonates transiently without developing collective oscillations. When the contrast is high, on the other hand, the induced activity undergoes synchronous oscillations with an irregular spatiotemporal structure expressing a synchronous chaotic state. As a consequence the population activity undergoes fast temporal decorrelation, with concomitant rapid damping of the oscillations in LFPs autocorrelograms and peak broadening in LFPs power spectra. We show that the strength of the inter-layer coupling crucially affects this spatiotemporal structure. We predict that layer VI inactivation should induce global changes in the spectral properties of induced LFPs, reflecting their slower temporal decorrelation in the absence of inter-layer feedback. Finally, we argue that the mechanism underlying the emergence of synchronous chaos in our model is in fact very general. It stems from the fact that gamma oscillations induced by local delayed

  7. Design of broad-band mixer on V-band%V波段宽带混频器的设计

    Institute of Scientific and Technical Information of China (English)

    宋翔; 年夫顺; 代秀

    2012-01-01

    Because of broad-band mixer's broad working band and low conversion loss,it is often used in communication, radar and microwave measurement systems. In this paper, the design and the performance of a V-band single balance mixer based on fin-line circuit are described. From the theory of the single balance mixer,the design of the single balance mixer-circuit and the structure of waveguide to fin line are expounded. Finally,the conversion loss of this mixer is less than 10 dBm and has a good flatness when the mixer's RF is sweeping from 50~75 GHz.%宽带混频器由于其工作带宽大,变频损耗低,在通信、雷达以及微波毫米波测试仪器等系统得到广泛的应用.介绍了一种V波段鳍线单平衡混频器的设计过程并给出了测试结果.从单平衡混频器的基本原理出发,阐述了鳍线单平衡混频电路和矩形波导到鳍线的过渡结构的设计.最后制作出的宽带混频器在射频频率为50~75 GHz的整个V波段内,变频损耗小于10 dBm,并有良好的变频损耗平坦度.

  8. X-Ray Emitting GHz-Peaked Spectrum Galaxies: Testing a Dynamical-Radiative Model with Broad-Band Spectra

    Energy Technology Data Exchange (ETDEWEB)

    Ostorero, L.; /Turin U. /INFN, Turin; Moderski, R.; /Warsaw, Copernicus Astron. Ctr. /KIPAC, Menlo Park; Stawarz, L.; /KIPAC, Menlo Park /Jagiellonian U., Astron. Observ.; Diaferio, A.; /Turin U. /INFN, Turin; Kowalska, I.; /Warsaw U. Observ.; Cheung, C.C.; /NASA, Goddard /Naval Research Lab, Wash., D.C.; Kataoka, J.; /Waseda U., RISE; Begelman, M.C.; /JILA, Boulder; Wagner, S.J.; /Heidelberg Observ.

    2010-06-07

    In a dynamical-radiative model we recently developed to describe the physics of compact, GHz-Peaked-Spectrum (GPS) sources, the relativistic jets propagate across the inner, kpc-sized region of the host galaxy, while the electron population of the expanding lobes evolves and emits synchrotron and inverse-Compton (IC) radiation. Interstellar-medium gas clouds engulfed by the expanding lobes, and photoionized by the active nucleus, are responsible for the radio spectral turnover through free-free absorption (FFA) of the synchrotron photons. The model provides a description of the evolution of the GPS spectral energy distribution (SED) with the source expansion, predicting significant and complex high-energy emission, from the X-ray to the {gamma}-ray frequency domain. Here, we test this model with the broad-band SEDs of a sample of eleven X-ray emitting GPS galaxies with Compact-Symmetric-Object (CSO) morphology, and show that: (i) the shape of the radio continuum at frequencies lower than the spectral turnover is indeed well accounted for by the FFA mechanism; (ii) the observed X-ray spectra can be interpreted as non-thermal radiation produced via IC scattering of the local radiation fields off the lobe particles, providing a viable alternative to the thermal, accretion-disk dominated scenario. We also show that the relation between the hydrogen column densities derived from the X-ray (N{sub H}) and radio (N{sub HI}) data of the sources is suggestive of a positive correlation, which, if confirmed by future observations, would provide further support to our scenario of high-energy emitting lobes.

  9. Synchronous chaos and broad band gamma rhythm in a minimal multi-layer model of primary visual cortex.

    Directory of Open Access Journals (Sweden)

    Demian Battaglia

    2011-10-01

    Full Text Available Visually induced neuronal activity in V1 displays a marked gamma-band component which is modulated by stimulus properties. It has been argued that synchronized oscillations contribute to these gamma-band activity. However, analysis of Local Field Potentials (LFPs across different experiments reveals considerable diversity in the degree of oscillatory behavior of this induced activity. Contrast-dependent power enhancements can indeed occur over a broad band in the gamma frequency range and spectral peaks may not arise at all. Furthermore, even when oscillations are observed, they undergo temporal decorrelation over very few cycles. This is not easily accounted for in previous network modeling of gamma oscillations. We argue here that interactions between cortical layers can be responsible for this fast decorrelation. We study a model of a V1 hypercolumn, embedding a simplified description of the multi-layered structure of the cortex. When the stimulus contrast is low, the induced activity is only weakly synchronous and the network resonates transiently without developing collective oscillations. When the contrast is high, on the other hand, the induced activity undergoes synchronous oscillations with an irregular spatiotemporal structure expressing a synchronous chaotic state. As a consequence the population activity undergoes fast temporal decorrelation, with concomitant rapid damping of the oscillations in LFPs autocorrelograms and peak broadening in LFPs power spectra. We show that the strength of the inter-layer coupling crucially affects this spatiotemporal structure. We predict that layer VI inactivation should induce global changes in the spectral properties of induced LFPs, reflecting their slower temporal decorrelation in the absence of inter-layer feedback. Finally, we argue that the mechanism underlying the emergence of synchronous chaos in our model is in fact very general. It stems from the fact that gamma oscillations induced by

  10. COMPARING BROAD-BAND AND RED EDGE-BASED SPECTRAL VEGETATION INDICES TO ESTIMATE NITROGEN CONCENTRATION OF CROPS USING CASI DATA

    Directory of Open Access Journals (Sweden)

    Y. Wang

    2016-06-01

    Full Text Available In recent decades, many spectral vegetation indices (SVIs have been proposed to estimate the leaf nitrogen concentration (LNC of crops. However, most of these indices were based on the field hyperspectral reflectance. To test whether they can be used in aerial remote platform effectively, in this work a comparison of the sensitivity between several broad-band and red edge-based SVIs to LNC is investigated over different crop types. By using data from experimental LNC values over 4 different crop types and image data acquired using the Compact Airborne Spectrographic Imager (CASI sensor, the extensive dataset allowed us to evaluate broad-band and red edge-based SVIs. The result indicated that NDVI performed the best among the selected SVIs while red edge-based SVIs didn’t show the potential for estimating the LNC based on the CASI data due to the spectral resolution. In order to search for the optimal SVIs, the band combination algorithm has been used in this work. The best linear correlation against the experimental LNC dataset was obtained by combining the 626.20nm and 569.00nm wavebands. These wavelengths correspond to the maximal chlorophyll absorption and reflection position region, respectively, and are known to be sensitive to the physiological status of the plant. Then this linear relationship was applied to the CASI image for generating an LNC map, which can guide farmers in the accurate application of their N fertilization strategies.

  11. Comparing Broad-Band and Red Edge-Based Spectral Vegetation Indices to Estimate Nitrogen Concentration of Crops Using Casi Data

    Science.gov (United States)

    Wang, Yanjie; Liao, Qinhong; Yang, Guijun; Feng, Haikuan; Yang, Xiaodong; Yue, Jibo

    2016-06-01

    In recent decades, many spectral vegetation indices (SVIs) have been proposed to estimate the leaf nitrogen concentration (LNC) of crops. However, most of these indices were based on the field hyperspectral reflectance. To test whether they can be used in aerial remote platform effectively, in this work a comparison of the sensitivity between several broad-band and red edge-based SVIs to LNC is investigated over different crop types. By using data from experimental LNC values over 4 different crop types and image data acquired using the Compact Airborne Spectrographic Imager (CASI) sensor, the extensive dataset allowed us to evaluate broad-band and red edge-based SVIs. The result indicated that NDVI performed the best among the selected SVIs while red edge-based SVIs didn't show the potential for estimating the LNC based on the CASI data due to the spectral resolution. In order to search for the optimal SVIs, the band combination algorithm has been used in this work. The best linear correlation against the experimental LNC dataset was obtained by combining the 626.20nm and 569.00nm wavebands. These wavelengths correspond to the maximal chlorophyll absorption and reflection position region, respectively, and are known to be sensitive to the physiological status of the plant. Then this linear relationship was applied to the CASI image for generating an LNC map, which can guide farmers in the accurate application of their N fertilization strategies.

  12. Modulations of broad-band radio continua and X-ray emissions in the large X-ray flare on 03 November 2003

    Science.gov (United States)

    Dauphin, C.; Vilmer, N.; Lüthi, T.; Trottet, G.; Krucker, S.; Magun, A.

    The GOES X3.9 flare on 03 November 2003 at ˜09:45 UT was observed from metric to millimetric wavelengths by the Nançay Radioheliograph (NRH), the Radio Solar Telescope Network (RSTN) and by radio instruments operated by the Institute of Applied Physics (University of Bern). This flare was simultaneously observed and imaged up to several 100 keV by the RHESSI experiment. The time profile of the X-ray emission above 100 keV and of the radio emissions shows two main parts, impulsive emission lasting about 3 min and long duration emission (partially observed by RHESSI) separated in time by 4 min. We shall focus here on the modulations of the broad-band radio continua and of the X-ray emissions observed in the second part of the flare. The observations suggest that gyrosynchrotron emission is the prevailing emission mechanism even at decimetric wavelengths for the broad-band radio emission. Following this interpretation, we deduce the density and the magnetic field of the decimetric sources and briefly comment on possible interpretations of the modulations.

  13. Broad-band coupling of THz radiation to an YBa2Cu3O7-δ hot-electron bolometer mixer

    International Nuclear Information System (INIS)

    We report on broad-band coupling of THz radiation to an YBa2Cu3O7-δ superconducting hot-electron bolometer. The bolometer - a micro-bridge of an YBa2Cu3O7-δ film with a PrBa2Cu3O7-δ protection layer - was built in a hybrid quasioptical antenna system consisting of a planar self-complementary spiral antenna on a dielectric substrate and an extended hyperhemispherical lens. The planar antenna was integrated into a coplanar transmission line for broad-band intermediate-frequency matching. Measurements performed in the direct detection regime between 2.5 THz and 4.2 THz delivered a system coupling efficiency for the radiation in the fundamental Gaussian mode of about 0.1 and a beam width of the radiation pattern of less than one degree. The pattern was consistent with the far-field radiation pattern that we calculated with a ray-tracing technique. At an intermediate frequency of 1.5 GHz we measured an output noise temperature of approx. 160 K for the bolometer driven in the resistive state by both dc and THz current and estimated, for the heterodyne regime, a system noise temperature of approx. 3x105 K. We studied the effect of a protection layer on the rate of phonon escape from the micro-bridge and, thus, on the output frequency bandwidth of the device. We discuss possibilities of a significant improvement of the device performance. (author)

  14. Imaging of the Deep Structure by Long Term Broad Band OBSs \\ \\ -- Trans-PHS Profile and NW Pacific WP-2 site --

    Science.gov (United States)

    Shiobara, H.; Sugioka, H.; Yoneshima, S.; Mochizuki, K.; Mochizuki, M.; Kodaira, S.; Hino, R.; Shinohara, M.; Kanazawa, T.; Fukao, Y.

    2001-12-01

    As an important part of the Ocean Hemisphere network Project, long term ocean bottom seismic observations have been started and some of their data have been retrieved already. One of them, the trans-Philippine Sea profile observation (15 Long Term OBSs, Nov. 1999 -- July 2000) was preliminarily reported at the last AGU fall meeting (S51B-02, 2000). Other long term broad band observations had been performed twice at the northwestern Pacific (Broad Band OBS, NWPAC1: Aug. 1999 -- May 2000, NWPAC2: May 2000 -- Nov. 2000), where the borehole seismic observatory (WP-2) has been activated in Nov. 2000. The LTOBS and the BBOBS contain a semi broad band sensor (WB2023LP, PMD) which has the pass band from 30s to 50Hz and a broad band sensor (CMG-1T, Guralp) which has the pass band from 360s to 80Hz, respectively. The seismic data is recorded continuously with a sampling frequency of 128Hz by a 20bit ADC on four 2.5 inch 6.5 GB HDDs. The direction of horizontal components are determined from the data of the direct water wave during the airgun shooting or P-SV converted waves at the sediment-basement interface. Running acceleration power spectra (0dB=1m2/s4/Hz) of these data during the whole observation period indicate followings; 1) sufficiently low noise band exists in the frequency range of 10--100mHz and the lowest level is close to the NLNM, but the horizontal noise level varies about 20--30dB with a dominant 12 hours interval, 2) high level micro seismic noise in the range of 0.1--1Hz is always near the NHNM and varies about 30--40dB. In this presentation, preliminary results of the deep structure imaging from these vast data by a receiver function analysis is shown. To perform this analysis with the OBS data, removal of water column reverberations and reduction of high level micro seismic noise should be necessary. The former process has a difficulty in the estimation of the water-sea bottom reflection coefficient and requires the data of higher sampling frequency, more

  15. Broad-band modelling of short gamma-ray bursts with energy injection from magnetar spin-down and its implications for radio detectability

    Science.gov (United States)

    Gompertz, B. P.; van der Horst, A. J.; O'Brien, P. T.; Wynn, G. A.; Wiersema, K.

    2015-03-01

    The magnetar model has been proposed to explain the apparent energy injection in the X-ray light curves of short gamma-ray bursts (SGRBs), but its implications across the full broad-band spectrum are not well explored. We investigate the broad-band modelling of four SGRBs with evidence for energy injection in their X-ray light curves, applying a physically motivated model in which a newly formed magnetar injects energy into a forward shock as it loses angular momentum along open field lines. By performing an order of magnitude search for the underlying physical parameters in the blast wave, we constrain the characteristic break frequencies of the synchrotron spectrum against their manifestations in the available multiwavelength observations for each burst. The application of the magnetar energy injection profile restricts the successful matches to a limited family of models that are self-consistent within the magnetic dipole spin-down framework. We produce synthetic light curves that describe how the radio signatures of these SGRBs ought to have looked given the restrictions imposed by the available data, and discuss the detectability of these signatures with present-day and near-future radio telescopes. Our results show that both the Atacama Large Millimeter Array (ALMA) and the upgraded Very Large Array are now sensitive enough to detect the radio signature within two weeks of trigger in most SGRBs, assuming our sample is representative of the population as a whole. We also find that the upcoming Square Kilometre Array will be sensitive to depths greater than those of our lower limit predictions.

  16. Broad-band monitoring tracing the evolution of the jet and disc in the black hole candidate X-ray binary MAXI J1659-152

    Science.gov (United States)

    van der Horst, A. J.; Curran, P. A.; Miller-Jones, J. C. A.; Linford, J. D.; Gorosabel, J.; Russell, D. M.; de Ugarte Postigo, A.; Lundgren, A. A.; Taylor, G. B.; Maitra, D.; Guziy, S.; Belloni, T. M.; Kouveliotou, C.; Jonker, P. G.; Kamble, A.; Paragi, Z.; Homan, J.; Kuulkers, E.; Granot, J.; Altamirano, D.; Buxton, M. M.; Castro-Tirado, A.; Fender, R. P.; Garrett, M. A.; Gehrels, N.; Hartmann, D. H.; Kennea, J. A.; Krimm, H. A.; Mangano, V.; Ramirez-Ruiz, E.; Romano, P.; Wijers, R. A. M. J.; Wijnands, R.; Yang, Y. J.

    2013-12-01

    MAXI J1659-152 was discovered on 2010 September 25 as a new X-ray transient, initially identified as a gamma-ray burst, but was later shown to be a new X-ray binary with a black hole as the most likely compact object. Dips in the X-ray light curves have revealed that MAXI J1659-152 is the shortest period black hole candidate identified to date. Here we present the results of a large observing campaign at radio, submillimetre, near-infrared (nIR), optical and ultraviolet (UV) wavelengths. We have combined this very rich data set with the available X-ray observations to compile a broad-band picture of the evolution of this outburst. We have performed broad-band spectral modelling, demonstrating the presence of a spectral break at radio frequencies and a relationship between the radio spectrum and X-ray states. Also, we have determined physical parameters of the accretion disc and put them into context with respect to the other parameters of the binary system. Finally, we have investigated the radio-X-ray and nIR/optical/UV-X-ray correlations up to ˜3 yr after the outburst onset to examine the link between the jet and the accretion disc, and found that there is no significant jet contribution to the nIR emission when the source is in the soft or intermediate X-ray spectral state, consistent with our detection of the jet break at radio frequencies during these states.

  17. Quantification of magnetic nanoparticles with broad-band-frequency magnetic susceptibility measurements: a case study of an upper loess/palaeosol succession at Luochuan, Chinese Loess Plateau

    Science.gov (United States)

    Kodama, Kazuto; An, Zhisheng; Chang, Hong; Qiang, Xiaoke

    2014-11-01

    Broad-band magnetic susceptibility (MS) measurement, a novel magnetic method capable of quantifying a narrow grain size distribution (GSD) of superparamagnetic (SP) particles by measuring low-field MS at a number of frequency steps spanning four orders of magnitude, has been tested in a loess/palaeosol section at Luochuan in the Chinese Loess Plateau. The studied succession consists of sequences from the latest palaeosol unit (S0) to the upper part of the loess unit (L2), spanning the last glacial-interglacial cycle. Reconstructed GSDs consist of volume fractions on the order of 10-24 m3, and the mean GSDs are modal but with distinctive skewness among the loess, the weakly developed palaeosols (weak palaeosols), and the mature palaeosols. This indicates that the mean volume of SP particles in this loess/palaeosol sequence tends to increase during the transition from loess → weak palaeosol → palaeosol, an indication of grain growth as pedogenesis progresses. Total frequency dependence, or TFD(per cent), the difference between χ130 at the lowest (130 Hz) and χ500k at the highest (500 kHz) frequencies normalized to χ130, is judged to be a more suitable index than previous frequency dependence parameters for the concentration of SP particles. TFD(per cent) has a strong correlation with χ130, showing a continuous `growth curve' with the rate of increase being highest for the loess, moderate for the weak palaeosols, and saturated for the palaeosols. The characteristic curve suggests that smaller SP particles are preferentially formed in the earlier stage of pedogenesis rather than the later phase when even larger particles are formed in mature palaeosols. These results demonstrate that the broad-band MS measurement method will be useful for the quantitative assessment of magnetic nanoparticles in soils and sediments.

  18. Penning trap at IGISOL

    Energy Technology Data Exchange (ETDEWEB)

    Szerypo, J. E-mail: jerzy.szerypo@phys.jyu.fi; Jokinen, A.; Kolhinen, V.S.; Nieminen, A.; Rinta-Antila, S.; Aeystoe, J

    2002-04-22

    The IGISOL facility at the Department of Physics of the University of Jyvaeskylae (JYFL) is delivering radioactive beams of short-lived exotic nuclei, in particular the neutron-rich isotopes from the fission reaction. These nuclei are studied with the nuclear spectroscopy methods. In order to substantially increase the quality and sensitivity of such studies, the beam should undergo beam handling: cooling, bunching and isobaric purification. The first two processes are performed with the use of an RFQ cooler/buncher. The isobaric purification will be made by a Penning trap placed after the RF-cooler element. This contribution describes the current status of the Penning trap project and its future prospects. The latter comprise the precise nuclear mass measurements, nuclear spectroscopy in the Penning trap interior as well as the laser spectroscopy on the extracted beams.

  19. 笔%Pen

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    @@ Small as it is,the pen has changed the course of history,shaped the destiny of nations,facilitated the commerce of peoples,imprisoned the elusive thoughts of man,recorded events,carried news,and done more work for mankind than all other tools or weapons.

  20. Comparison of broad band time series recorded parallel by FGI type interferometric water level and Lippmann type pendulum tilt meters at Conrad observatory, Austria

    Science.gov (United States)

    Ruotsalainen, Hannu; Papp, Gabor; Leonhardt, Roman; Ban, Dora; Szücs, Eszter; Benedek, Judith

    2016-04-01

    The Finnish Geodetic Institute (FGI) the progenitor of Finnish Geospatial Research Institute of NLS designed and built a 5.5m long prototype of interferometric water level tiltmeter (iWT) in early 2014. Geodetic and Geophysical Institute (GGI), Sopron, Hungary bought the instrument and started tilt measurement in August 2014 at the Conrad observatory (COBS), Austria to monitor geodynamical phenomena like microseisms, free oscillations of the Earth, earth tides, mass loading effects and crustal deformations in cooperation with Austrian Central Institute for Meteorology and Geodynamics (ZAMG) and the FGI. On the July 16 2015 a Lippmann-type 2D tilt sensor (LTS) was also installed by GGI on the 6 m long pier where iWT was set up previously. This situation opens a possibility to do broad band (from secular to seismic variations up to 15 Hz) geophysical signal analysis comparing the responses of long (several meters) and short (a few decimeters) base instruments implementing different physical principles (relative height change of a level surface and inclination change of the plumb line). The characteristics of the sensors are studied by the evaluation of the spectra of recorded signals dominated by microseisms. The iWT has internal interferometric calibration and it can be compared to Lippmanns tilt meter one. Both instruments show good long term ( > 1 day) stability when earth tides and ocean and air mass loading tilts are modelled.

  1. Contamination of Broad-Band Photometry by Nebular Emission in High Redshift Galaxies: Investigations with Keck's MOSFIRE Near-Infrared Spectrograph

    CERN Document Server

    Schenker, Matthew A; Konidaris, Nick P; Stark, Daniel P

    2013-01-01

    Earlier work has raised the potential importance of nebular emission in the derivation of the physical characteristics of high redshift Lyman break galaxies. Within certain redshift ranges, and especially at z ~ 6-7, such lines may be strong enough to reduce estimates of the stellar masses and ages of galaxies compared those derived assuming broad-band photometry represents stellar light alone. To test this hypothesis at the highest redshifts where such lines can be probed with ground-based facilities, we examine the near-infrared spectra of a representative sample of 20 3.0 < z < 3.8 Lyman break galaxies using the newly-commissioned MOSFIRE near-infrared spectrograph at the Keck I telescope. We use this data to derive the rest-frame equivalent widths (EW) of [O III] emission and show that these are comparable to estimates derived using the SED fitting technique introduced for sources of known redshift by Stark et al (2013). Although our current sample is modest, its [O III] EW distribution is consisten...

  2. Broad-band spectrophotometry of the hot Jupiter HAT-P-12b from the near-UV to the near-IR

    CERN Document Server

    Mallonn, M; Weingrill, J; von Essen, C; Strassmeier, K G; Piotto, G; Pagano, I; Scandariato, G; Csizmadia, Sz; Herrero, E; Sada, P V; Dhillon, V S; Marsh, T R; Künstler, A; Bernt, I; Granzer, T

    2015-01-01

    The detection of trends or gradients in the transmission spectrum of extrasolar planets is possible with observations at very low spectral resolution. Transit measurements of sufficient accuracy using selected broad-band filters allow for an initial characterization of the atmosphere of the planet. We obtained time series photometry of 20 transit events and analyzed them homogeneously, along with eight light curves obtained from the literature. In total, the light curves span a range from 0.35 to 1.25 microns. During two observing seasons over four months each, we monitored the host star to constrain the potential influence of starspots on the derived transit parameters. We rule out the presence of a Rayleigh slope extending over the entire optical wavelength range, a flat spectrum is favored for HAT-P-12b with respect to a cloud-free atmosphere model spectrum. A potential cause of such gray absorption is the presence of a cloud layer at the probed latitudes. Furthermore, in this work we refine the transit pa...

  3. A Decade of Short-duration Gamma-ray Burst Broad-band Afterglows: Energetics, Circumburst Densities, and Jet Opening Angles

    CERN Document Server

    Fong, Wen-fai; Margutti, Raffaella; Zauderer, B Ashley

    2015-01-01

    We present a comprehensive catalog and analysis of broad-band afterglow observations for 103 short-duration gamma-ray bursts (GRBs), comprised of all short GRBs from November 2004 to March 2015 with prompt follow-up observations in the X-ray, optical, near-infrared and/or radio bands. These afterglow observations have uncovered 71 X-ray detections, 30 optical/NIR detections, and 4 radio detections. Employing the standard afterglow synchrotron model, we perform joint probability analyses for a subset of 38 short GRBs with well-sampled light curves to infer the burst isotropic-equivalent energies and circumburst densities. For this subset, we find median isotropic-equivalent gamma-ray and kinetic energies of E_gamma,iso~2x10^51 erg, and E_K,iso~(1-3)x10^51 erg, respectively, depending on the values of the model input parameters. We further find that short GRBs occur in low-density environments, with a median density of n~(3-15)x10^-3 cm^-3, and that ~80-95% of bursts have densities of less than 1 cm^-3. We inve...

  4. 5.5-MeV proton irradiation of a strained quantum-well laser diode and a multiple quantum-well broad-band LED

    International Nuclear Information System (INIS)

    The degradation under 5.5-MeV proton irradiation of two classes of quantum-well-based fiber-optic light sources was evaluated for satellite applications. The first was an InGaAs/GaAs strained-layer quantum-well (QW) laser; the second was a broad-band light-emitting diode (LED) based on dual asymmetric quantum wells in the InGaAs/GaAs/AlGaAs system. In contrast to earlier reports comparing bulk active-region heterostructure LEDs with similarly structured laser diodes, these QW LEDs were more tolerant of proton irradiation (-3dB power at ∼3x1013 protons/cm2) than the QW lasers (-3dB power at ∼3x1012 protons/cm2). The LEDs were operated far into gain saturation with a high-loss cavity structure, while the lasers were operated in a region where gain was more sensitive to current density. Therefore atomic displacement-related recombination sites had a greater detrimental effect upon the lasers than the LEDs. The lasers held constant slope efficiency, and current thresholds increased linearly with proton fluence, while both LED power and slope efficiency decreased with proton fluence. Similar damage factors were found to those predicted from a universal damage factor versus non-ionizing energy deposition relation reported by others, and appears to extend that relation to include these QW photonic devices

  5. Sensitivity of broad-band ground-motion simulations to earthquake source and Earth structure variations: an application to the Messina Straits (Italy)

    KAUST Repository

    Imperatori, W.

    2012-03-01

    In this paper, we investigate ground-motion variability due to different faulting approximations and crustal-model parametrizations in the Messina Straits area (Southern Italy). Considering three 1-D velocity models proposed for this region and a total of 72 different source realizations, we compute broad-band (0-10 Hz) synthetics for Mw 7.0 events using a fault plane geometry recently proposed. We explore source complexity in terms of classic kinematic (constant rise-time and rupture speed) and pseudo-dynamic models (variable rise-time and rupture speed). Heterogeneous slip distributions are generated using a Von Karman autocorrelation function. Rise-time variability is related to slip, whereas rupture speed variations are connected to static stress drop. Boxcar, triangle and modified Yoffe are the adopted source time functions. We find that ground-motion variability associated to differences in crustal models is constant and becomes important at intermediate and long periods. On the other hand, source-induced ground-motion variability is negligible at long periods and strong at intermediate-short periods. Using our source-modelling approach and the three different 1-D structural models, we investigate shaking levels for the 1908 Mw 7.1 Messina earthquake adopting a recently proposed model for fault geometry and final slip. Our simulations suggest that peak levels in Messina and Reggio Calabria must have reached 0.6-0.7 g during this earthquake.

  6. Virial Black Hole Mass Estimates for 280,000 AGNs from the SDSS Broad-Band Photometry and Single Epoch Spectra

    CERN Document Server

    Kozłowski, Szymon

    2016-01-01

    We use the Sloan Digital Sky Survey (SDSS) Quasar Data Release 12 (DR12Q), containing nearly 300,000 AGNs, to calculate the monochromatic luminosities at 5100\\AA, 3000\\AA, and 1350\\AA, derived from the broad-band extinction-corrected SDSS magnitudes. After matching them to their counterparts based on spectra and published in the SDSS Quasar Data Release 7 (DR7Q), we find perfect correlations with minute mean offsets ($\\sim$0.01 dex) and dispersions of differences of 0.11, 0.10, 0.12 dex, respectively, across a 2.5 dex luminosity range. We then estimate the active galactic nuclei (AGNs) black hole masses using the broad line region radius--luminosity relations and the FWHM of the MgII and CIV emission lines, to provide a catalog of 283,032 virial black hole mass estimates (132,451 for MgII, 213,068 for CIV, and 62,487 for both) along with the bolometric luminosity and the Eddington ratio estimates for $0.1

  7. ASCA Observations of the Starburst-Driven Superwind Galaxy NGC 2146 Broad Band (0.6 - 9 keV) Spectral Properties

    CERN Document Server

    Ceca, R D; Heckman, T M; Lehnert, M D; Weaver, K A

    1998-01-01

    We report ASCA GIS and SIS observations of the nearby (D = 11.6 Mpc), nearly edge-on, starburst galaxy NGC 2146. These X-ray spectral data complement ROSAT PSPC and HRI imaging discussed by Armus et al., 1995. The broad band (0.6-9 keV) X-ray spectrum of NGC 2146 is best described by a two component model: the soft X-ray emission with a Raymond-Smith thermal plasma model having a temperature of kT $\\sim 0.8$ keV; the hard X-ray emission with a thermal plasma model having kT $\\sim 8$ keV or a power-law model having a photon index of above the Galactic value. The soft (hard) thermal component provides about 30% (70%) of the total luminosity in the 0.5 - 2.0 keV energy band, while in the 2-10 keV energy range only the hard component plays a major role. The spectral results allow us to set tighter constraints on the starburst-driven superwind model, which we show can satisfactorily account for the luminosity, mass, and energy content represented by the soft X-ray spectral component. We estimate that the mass outf...

  8. INTEGRAL discovery of unusually long broad-band X-ray activity from the Supergiant Fast X-ray Transient IGR J18483-0311

    CERN Document Server

    Sguera, V; Bird, A J; Bazzano, A

    2015-01-01

    We report on a broad-band X-ray study (0.5-250 keV) of the Supergiant Fast X-ray Transient IGR J18483-0311 using archival INTEGRAL data and a new targeted XMM-Newton observation. Our INTEGRAL investigation discovered for the first time an unusually long X-ray activity (3-60 keV) which continuously lasted for at least 11 days, i.e. a significant fraction (about 60%) of the entire orbital period, and spanned orbital phases corresponding to both periastron and apastron passages. This prolongated X-ray activity is at odds with the much shorter durations marking outbursts from classical SFXTs especially above 20 keV, as such it represents a departure from their nominal behavior and it adds a further extreme characteristic to the already extreme SFXT IGR J18483-0311. Our IBIS/ISGRI high energy investigation (100-250 keV) of archival outbursts activity from the source showed that the recently reported hint of a possible hard X-ray tail is not real and it is likely due to noisy background. The new XMM-Newton targeted...

  9. Modelling the variable broad-band optical/UV/X-ray spectrum of PG1211+143: Implications for the ionized outflow

    CERN Document Server

    Papadakis, I E; Panagiotou, C

    2016-01-01

    We present the results from a detailed analysis of the 2007 Swift monitoring campaign of the quasar PG1211+143. We constructed broad-band, optical/UV/X-ray spectral energy distributions over three X-ray flux intervals. We fitted them with a model which accounts for the disc and the X-ray coronal emission and the warm absorber (well established in this source). The three flux spectra are well fitted by the model we considered. The disc inner temperature remains constant at ~2 eV, while X-rays are variable both in spectral slope and normalization. The absorber covers almost 90% of the central source. It is outflowing with a velocity less than 2.3*10^4 km/s (3sigma upper limit), and has a column density of ~10^23.2. Its ionization parameter varies by a factor of 1.6, and it is in photo-ionizing equilibrium with the ionizing flux. It is located at a distance of less than 0.35 pc from the central source and its relative thickness, DR/R is less than 0.1. The absorber' s ionization parameter variations can explain t...

  10. Pen-side testing

    International Nuclear Information System (INIS)

    Pen-side diagnostic testing is often required to provide real time information about the health status of an animal or herd. The rapid results are generally needed in the face of a disease outbreak where the diagnostician/clinician is presented with dead or dying animals. Another use of pen-side tests is as part of a preventive medicine/herd health programme, where the information can be used for determining pathogen incidence and prevalence in the herd, identifying potential carrier animals or evaluating subtle changes in overall herd health as a result of management changes. Still another area is as a part of health certification before sale or stocking, or during processing following slaughter. Advanced testing methods, which in the past were only appropriate for use in a laboratory setting, have now been formatted for use in the field. Enzyme immunoassays (EIAs) and immunochromatorgraphy have greatly enhanced diagnostic pen-side capabilities. These test systems allow for the rapid, sensitive and specific detection of target antigen or antibody and require little or no scientific equipment. Because of the wide format flexibility these immunochemical technologies allow, they have come to dominate the diagnostic industry, both in the laboratory and in the field. Using liquid phase or precipitating chromogens, the tests can be visually interpreted and do not need instrumentation. Immunochromatography, a simplified assay system, has found widespread application as a field or pen-side test. The entire assay takes only one or two steps, and the results appear within 5-10 minutes. In the future, DNA based diagnostics will become more adaptable for use in the field. The DNA hybridization systems are at present cumbersome and require elevated temperatures. Companies are currently working to develop fast formulas that provide results in less than an hour, have a limited number of steps and can be performed at lower temperatures. (author)

  11. Modelling the variable broad-band optical/UV/X-ray spectrum of PG1211+143: implications for the ionized outflow

    Science.gov (United States)

    Papadakis, I. E.; Nicastro, F.; Panagiotou, C.

    2016-06-01

    Context. We present the results from a detailed analysis of the 2007 Swift monitoring campaign of the quasar PG1211+143. Aims: We study its broad-band optical/UV-X-ray spectral energy distribution and its variations, with the use of physically motivated models. Methods: We constructed broad-band, optical/UV-X-ray spectral energy distributions over three X-ray flux intervals, and we fitted them with a model which accounts for the disc and the X-ray coronal emission. We also added a spectral model component to account for the presence of the warm absorber which has been well established from past observations of the source. Results: We detected no optical/UV variations over the two-month period of the monitoring campaign. On the other hand, the X-rays are highly variable in a correlated way in the soft and hard X-ray bands with an amplitude larger than has been commonly observed in nearby Seyferts, even on longer time scales. The three flux spectra are well fitted by the model we considered. The disc inner temperature remains constant at ~2 eV, while X-rays are variable in slope and normalization. The absorber covers almost 90% of the central source. It is outflowing with a velocity less than 2.3 × 104 km s-1 (3σ upper limit), and has a column density of log NH ~ 23.2. Its ionization parameter varies by a factor of 1.6, and it is in photo-ionizing equilibrium with the ionizing flux. It is located at a distance of less than 0.35 pc from the central source, and its relative thickness, ΔR/R, is less than 0.1. The absorber's ionization parameter variations can explain the larger than average amplitude of the X-ray variations. Conclusions: The absence of optical/UV variations are consistent with the high black hole mass estimate of ~108M⊙ for this object, which implies variability time scales longer than the period of the Swift observations. It argues against the presence of inward propagating fluctuations in the disc as the reason for the flux variability in this

  12. Broad-band spectrophotometry of the hot Jupiter HAT-P-12b from the near-UV to the near-IR

    Science.gov (United States)

    Mallonn, M.; Nascimbeni, V.; Weingrill, J.; von Essen, C.; Strassmeier, K. G.; Piotto, G.; Pagano, I.; Scandariato, G.; Csizmadia, Sz.; Herrero, E.; Sada, P. V.; Dhillon, V. S.; Marsh, T. R.; Künstler, A.; Bernt, I.; Granzer, T.

    2015-11-01

    Context. The detection of trends or gradients in the transmission spectrum of extrasolar planets is possible with observations at very low spectral resolution. Transit measurements of sufficient accuracy using selected broad-band filters allow for an initial characterization of the atmosphere of the planet. Aims: We want to investigate the atmosphere of the hot Jupiter HAT-P-12b for an increased absorption at the very blue wavelength regions caused by scattering. Furthermore, we aim for a refinement of the transit parameters and the orbital ephemeris. Methods: We obtained time series photometry of 20 transit events and analyzed them homogeneously, along with eight light curves obtained from the literature. In total, the light curves span a range from 0.35 to 1.25 microns. During two observing seasons over four months each, we monitored the host star to constrain the potential influence of starspots on the derived transit parameters. Results: We rule out the presence of a Rayleigh slope extending over the entire optical wavelength range, a flat spectrum is favored for HAT-P-12b with respect to a cloud-free atmosphere model spectrum. A potential cause of such gray absorption is the presence of a cloud layer at the probed latitudes. Furthermore, in this work we refine the transit parameters, the ephemeris and perform a TTV analysis in which we found no indication for an unseen companion. The host star showed a mild non-periodic variability of up to 1%. However, no stellar rotation period could be detected to high confidence.

  13. Seismic source study of the 1989, October 29, Chenoua (Algeria earthquake from aftershocks, broad-band and strong ground motion records

    Directory of Open Access Journals (Sweden)

    L. Rivera

    2003-06-01

    Full Text Available The broad-band teleseismics records of the earthquake of October 29,1989 in Algeria (MW = 6.0 allow a detailed study of the rupture process of this earthquake. The focal mechanism obtained by P and SH modeling corresponds to reverse faulting with a small amount of left-lateral movement along a fault striking 246° and dipping 56°. The rupture is found to be complex with two sub-events separated in time but occurring on the same plane. The lowfrequency records of an accelerometer located some 25 km to the west of the main shock are also better fi tted when the rupture is composed of a double pulse. In the two cases, there is strong evidence for the rupture to propagate from south-west towards north-east.The relocalisation of the main shock by using a master-event technique and the data from Italian and Spanish stations led to the same conclusions. Soon after the main event, a temporary seimic network was installed in the epicentral area. The aftershock clouds defi ne a SW-NE fault dipping to the NW compatible with the results of the modelisations of the teleseismic body-waves and the accelerogram. The focal mechanisms correspond mainly to reverse faulting. The maximum principal direction of the stress tensor obtained from the inversion is about N-S and the minimum is vertical, typical of a compressive regime. The Chenoua earthquake took place on a fault which was not recognized as active. Repeated comparable seismic events on this fault and on the fault that borders the massif to the south explain this intriguing topographic feature.

  14. Dynamics of the 2007 Eruptions of Piton de la Fournaise and the Related Caldera Collapse from a Single Very Broad-band Seismic Station

    Science.gov (United States)

    Fontaine, Fabrice R.; Roult, Geneviève; Michon, Laurent; Barruol, Guilhem; Ferrazzini, Valérie; Di Muro, Andrea; Reymond, Dominique; Peltier, Aline; Staudacher, Thomas

    2014-05-01

    Seismic records from the RER very broad-band seismic station (La Réunion Island) belonging to the GEOSCOPE network are investigated to understand the eruptive succession (February to May) of Piton de la Fournaise and the caldera collapse episode of April 2007. Data first indicate that the short-lived, small volume, summit eruption of February 18 occurred during a phase of continuous inflation initiated in January 2007. Inflation decelerated around 2 weeks before a second short-lived small volume eruption on March 30-31 on the SE flank, almost simultaneous with a sudden, large deflation of the edifice. Deflation rate, which had stabilized at a relatively low level, increased anew on April 1 while no magma was emitted, followed on April 2 by a more distant and one of the most voluminous eruptions of the last two centuries at La Réunion Island. The RER station shows that very long period (VLP) and ultra long period (ULP) events developed during this period. Seven ULP events preceded the caldera collapse and 48 ones occurred during the caldera collapse over 9 days, most of which during the first 30 hours. A thorough examination of the seismic signals corrected for tide effects shows that each collapse event was coeval with VLP and ULP signals. Each individual collapse showed similar ULP and VLP signals characterized by periods of ~ 500 s and ~ 7 s, respectively. The back-azimuth of most ULP signals related to the caldera collapse points clearly toward the Dolomieu caldera. The strikingly constant duration of the VLP signals (around 20 s) related to the collapse events and their occurrence before the collapse initiation suggest a physical control of the volcanic edifice. Waveforms and spectrograms of the various caldera collapse events show very homogeneous patterns, suggesting a similar and repeating volcano-tectonic process for the formation of the VLP signals events. Although tilt may be responsible of part of the ULP signals observed during the collapse events, we

  15. 雾化幕障宽波段消光性能研究%Study on broad band extinction performance of atomized screen

    Institute of Scientific and Technical Information of China (English)

    杜雪峰; 潘功配; 曲家惠; 赵新颖; 张旗

    2015-01-01

    A new jamming technology of atomized screen was studied to overcome the shortcomings of existing broad band jamming technology, such as the short acting time and the narrow jamming wave band. The theory of multiband jamming and the formula of atomized screen was introduced. The jamming effect on multiband such as visible light, laser, infrared, millimeter wave radar and centimeter wave radar has been tested. Necessary theory and experimental data were provided for the application of this technology. The experimental results show that visible light and laser could be shielded when the foam diameter of atomized screen was 2- 3 mm and the thickness was 50 cm. Under the same conditions, the transmission of infrared was less than 5%, and the good screening effect was achieved on millimeter wave radar and centimeter wave radar. The high efficiency interfering time was above 20 min. The study shows that the new atomized screen was a potential wide frequency passive interfering medium.%现有宽波段干扰技术普遍存在作用时间太短、干扰波段不够宽等问题,为此研究了新型的雾化幕障干扰技术。研究了其多波段干扰原理、原料配方,并针对可见光、激光、红外、毫米波和厘米波波段光源进行消光性能实验研究。实验结果表明:泡径为2~3 mm厚50 cm的雾化幕障,可完全屏蔽可见光和激光信号,红外透过率小于5%;对毫米波和厘米波信号也能达到良好的遮蔽效果,高效干扰时间在20 min以上,是一种有潜质的宽频无源干扰介质。

  16. Improvement of penning ion sources

    CERN Document Server

    Bizyukov, A A; Kashaba, A Y; Sereda, K N

    2000-01-01

    It is shown that the loss of a longitudinal symmetry of magnetic field distribution in respect to the centre of the Penning discharge system causes change of electrostatic potential distribution in the discharge gap leads to appearance of asymmetry of current magnitude to the cathodes of the Penning cell,change of magnitude of current density and energy distribution of the ion beam extracted in a longitudinal direction.The use of an inhomogeneous magnetic field which is longitudinally asymmetrical concerning electrodes of the system allows to increase current efficiency of Penning ion sources from 0,2 to 0,55.

  17. Multi-Segment Direct Inject nano-ESI-LTQ-FT-ICR-MS/MS For Protein Identification

    Directory of Open Access Journals (Sweden)

    Neal Rachel E

    2011-07-01

    Full Text Available Abstract Reversed phase high performance liquid chromatography (HPLC interfaced to electrospray tandem mass spectrometry (MS/MS is commonly used for the identification of peptides from proteolytically cleaved proteins embedded in a polyacrylamide gel matrix as well as for metabolomics screening. HPLC separations are time consuming (30-60 min average, costly (columns and mobile phase reagents, and carry the risk of column carry over between samples. The use of a chip-based nano-ESI platform (Advion NanoMate based on replaceable nano-tips for sample introduction eliminates sample cross-contamination, provides unchanging sample matrix, and enhances spray stability with attendant increases in reproducibility. Recent papers have established direct infusion nano-ESI-MS/MS utilizing the NanoMate for protein identification of gel spots based on full range MS scans with data dependent MS/MS. In a full range scan, discontinuous ion suppression due to sample matrix can impair identification of putative mass features of interest in both the proteomic and metabolomic workflows. In the current study, an extension of an established direct inject nano-ESI-MS/MS method is described that utilizes the mass filtering capability of an ion-trap for ion packet separation into four narrow mass ranges (50 amu overlap with segment specific dynamic data dependent peak inclusion for MS/MS fragmentation (total acquisition time of 3 minutes. Comparison of this method with a more traditional nanoLC-MS/MS based protocol utilizing solvent/sample stream splitting to achieve nanoflow demonstrated comparable results for protein identification from polyacrylamide gel matrices. The advantages of this method include full automation, lack of cross-contamination, low cost, and high throughput.

  18. Advanced Mass Calibration and Visualization for FT-ICR Mass Spectrometry Imaging

    OpenAIRE

    Smith, Donald F.; Kharchenko, Andriy; Konijnenburg, Marco; Klinkert, Ivo; Pasa-Tolic, Ljiljana; Ron M A Heeren

    2013-01-01

    Mass spectrometry imaging by Fourier transform ion cyclotron resonance yields hundreds of unique peaks, many of which cannot be resolved by lower performance mass spectrometers. The high mass accuracy and high mass resolving power allow confident identification of small molecules and lipids directly from biological tissue sections. Here, calibration strategies for Fourier transform ion cyclotron resonance mass spectrometry imaging were investigated. Sub parts-per-million mass accuracy is demo...

  19. Advanced Mass Calibration and Visualization for FT-ICR Mass Spectrometry Imaging

    CERN Document Server

    Smith, Donald F; Konijnenburg, Marco; Klinkert, Ivo; Pasa-Tolic, Ljiljana; Heeren, Ron M A

    2013-01-01

    Mass spectrometry imaging by Fourier transform ion cyclotron resonance yields hundreds of unique peaks, many of which cannot be resolved by lower performance mass spectrometers. The high mass accuracy and high mass resolving power allow confident identification of small molecules and lipids directly from biological tissue sections. Here, calibration strategies for Fourier transform ion cyclotron resonance mass spectrometry imaging were investigated. Sub parts-per-million mass accuracy is demonstrated over an entire tissue section. Ion abundance fluctuations are corrected for by addition of total and relative ion abundances for a root-mean-square error of 0.158 ppm on 16,764 peaks. A new approach for visualization of Fourier transform ion cyclotron resonance mass spectrometry imaging data at high resolution is presented. The Mosaic Data-cube provides a flexible means to visualize the entire mass range at a mass spectral bin width of 0.001 Dalton. The high resolution Mosaic Data-cube resolves spectral features ...

  20. Mylan to Offer Generic EpiPen

    Science.gov (United States)

    ... news/fullstory_160669.html Mylan to Offer Generic EpiPen Manufacturer responds to mounting criticism about price hikes ... cheaper generic version of the emergency allergy treatment EpiPen will be made available within the next few ...

  1. 基于FPGA的宽带多普勒测速声纳数字系统的设计与实现%Design and implementation of the digital system of broad band Doppler velocity measuring sonar based on FPGA

    Institute of Scientific and Technical Information of China (English)

    杨威; 李迪; 赵极远

    2012-01-01

    针对多普勒测速声纳的高精度要求,采用宽带发射信号和相控阵波束形成技术,并利用FPGA在数据处理方面高速、并行、实时的特点,在以Altera StratixⅡ EP2S60F48414 FPGA为核心的系统上设计了宽带多普勒测速声纳数字系统,实现了采样控制及带通滤波、波束形成、相关运算等信号处理算法.测试结果显示,宽带信号能够更好地满声纳系统高精度要求.%To meet the high precision of the doppler velocity measuring sonar, the broad band transmitting signal and phased -array are used, also with the high speed, parallel, real-time characteristic of processing data by FPGAs, the digital system of the Doppler velocity measuring sonar is designed and implemented on the core of Altera's Stratixll EP2S60F484I4 FPGA , the sampling control, band-pass filtering, beam forming, correlation operation and other signal processing algorithms have been realized . Meanwhile, the test results show that the broad band signal can meet the high precision of sonar system better.

  2. Broad-band multisection electrooptic modulators

    Science.gov (United States)

    Lax, Benjamin; Marino, Richard M.; Eng, Richard S.

    1988-10-01

    A general solution has been derived for expressing the conversion of power from a base frequency to a modulation sideband using a multisection electrooptic modulator. The objective is to obtain broadband frequency modulation of a laser by the use of multiple collinear electrooptic crystals with microwave power levels well below the breakdown threshold. It is found that segmented structures lead to greater bandwidths, which increase with the number of modulator sections. This is achieved by adjusting the phases of microwaves between sections to maximize the single-sideband conversion efficiency. It is shown that a 10.6-micron CO2 laser modulator with six geometrically identical CdTe sections can potentially achieve a 3-dB bandwidth of nearly 6 GHz using a 10-kW traveling-wave tube operating at 16-GHz center frequency.

  3. Broad band acoustic spectroscopy in disordered systems

    OpenAIRE

    Battistoni, Andrea

    2015-01-01

    The present work of thesis is situated within the framework of the study of disordered systems as liquids and glasses. A liquid is a system characterized by long range translational invariance and by a short range ordered structure. In the liquid state, contrarily to the crystalline one, there is not structural periodicity and all we learnt from solid state physics (Block’s theorem, phonons, Brillouin’s zones, eigen-states of plane waves, etc.) must be fully revised. The mac...

  4. Broad band sound from wind turbine generators

    Science.gov (United States)

    Hubbard, H. H.; Shepherd, K. P.; Grosveld, F. W.

    1981-01-01

    Brief descriptions are given of the various types of large wind turbines and their sound characteristics. Candidate sources of broadband sound are identified and are rank ordered for a large upwind configuration wind turbine generator for which data are available. The rotor is noted to be the main source of broadband sound which arises from inflow turbulence and from the interactions of the turbulent boundary layer on the blade with its trailing edge. Sound is radiated about equally in all directions but the refraction effects of the wind produce an elongated contour pattern in the downwind direction.

  5. Broad-band X-ray emission and the reality of the broad iron line from the neutron star-white dwarf X-ray binary 4U 1820-30

    Science.gov (United States)

    Mondal, Aditya S.; Dewangan, G. C.; Pahari, M.; Misra, R.; Kembhavi, A. K.; Raychaudhuri, B.

    2016-09-01

    Broad relativistic iron lines from neutron star X-ray binaries are important probes of the inner accretion disc. The X-ray reflection features can be weakened due to strong magnetic fields or very low iron abundances such as is possible in X-ray binaries with low mass, first generation stars as companions. Here, we investigate the reality of the broad iron line detected earlier from the neutron-star low-mass X-ray binary 4U 1820-30 with a degenerate helium dwarf companion. We perform a comprehensive, systematic broad-band spectral study of the atoll source using Suzaku and simultaneous NuSTAR and Swift observations. We have used different continuum models involving accretion disc emission, thermal blackbody and thermal Comptonization of either disc or blackbody photons. The Suzaku data show positive and negative residuals in the region of Fe K band. These features are well described by two absorption edges at 7.67 ± 0.14 keV and 6.93 ± 0.07 keV or partial covering photoionized absorption or by blurred reflection. Though, the simultaneous Swift and NuSTAR data do not clearly reveal the emission or absorption features, the data are consistent with the presence of either absorption or emission features. Thus, the absorption based models provide an alternative to the broad iron line or reflection model. The absorption features may arise in winds from the inner accretion disc. The broad-band spectra appear to disfavour continuum models in which the blackbody emission from the neutron-star surface provides the seed photons for thermal Comptonization. Our results suggest emission from a thin accretion disc (kTdisc ˜ 1 keV), Comptonization of disc photons in a boundary layer most likely covering a large fraction of the neutron-star surface and innermost parts of the accretion disc, and blackbody emission (kTbb ˜ 2 keV) from the polar regions.

  6. Vegetation survey of PEN Branch wetlands

    Energy Technology Data Exchange (ETDEWEB)

    1991-01-01

    A survey was conducted of vegetation along Pen Branch Creek at Savannah River Site (SRS) in support of K-Reactor restart. Plants were identified to species by overstory, understory, shrub, and groundcover strata. Abundance was also characterized and richness and diversity calculated. Based on woody species basal area, the Pen Branch delta was the most impacted, followed by the sections between the reactor and the delta. Species richness for shrub and groundcover strata were also lowest in the delta. No endangered plant species were found. Three upland pine areas were also sampled. In support of K Reactor restart, this report summarizes a study of the wetland vegetation along Pen Branch. Reactor effluent enters Indian Grove Branch and then flows into Pen Branch and the Pen Branch Delta.

  7. Synthesis and luminescence properties of a broad-band red phosphor Ca{sub 3}Si{sub 2}O{sub 7}:Eu{sup 2+} for warm white light-emitting diodes

    Energy Technology Data Exchange (ETDEWEB)

    Qian Fengjiao [College of Materials Science and Technology, Nanjing University of Aeronautics and Astronautics, Nanjing 210016 (China); Fu Renli, E-mail: renlifu@nuaa.edu.cn [College of Materials Science and Technology, Nanjing University of Aeronautics and Astronautics, Nanjing 210016 (China); Agathopoulos, Simeon [Materials Science and Engineering Department, University of Ioannina, GR-451 10 Ioannina (Greece); Gu Xiguang; Song Xiufeng [College of Materials Science and Technology, Nanjing University of Aeronautics and Astronautics, Nanjing 210016 (China)

    2012-01-15

    Single-phase broad-band red-emitting Ca{sub 3}Si{sub 2}O{sub 7}:Eu{sup 2+} phosphors, with photoluminescence features that qualify them as candidates for white light-emitting diodes applications, were successfully synthesized via a modified solid-state reaction method that employed H{sub 3}BO{sub 3} as a flux. The phosphors produced have an intense broad red emission band, with a peak at 603 nm, a full width at half maximum of 110 nm, and color coordinates of (0.550, 0.438). Concentration quenching occurred at 0.01 mol Eu{sup 2+}. The discussion of the results shows that Eu{sup 2+} ions should be accommodated at the Ca-sites of the lattice, dipole-dipole interactions should predominantly govern the energy transfer mechanism among them, and the critical distance between them is {approx}31 A. - Highlights: > Pure Ca{sub 3}Si{sub 2}O{sub 7}:Eu{sup 2+} phosphor was successfully synthesized by adding H{sub 3}BO{sub 3} . > Effects of H{sub 3}BO{sub 3} on phase formation and emission intensity were presented. > Luminescence properties in conjunction with Ca{sub 3}Si{sub 2}O{sub 7} structure were studied. > Energy transfer mechanism of Eu{sup 2+} and its critical distance were proposed.

  8. Erfahrungen mit einem C-Pen

    OpenAIRE

    Ziegler, Christoph

    2002-01-01

    Gemeinsamer Workshop von Universitaetsrechenzentrum und Professur Rechnernetze und verteilte Systeme der Fakultaet fuer Informatik der TU Chemnitz. Der Vortrag beginnt mit der Vorstellung eines C-Pen. Erfahrungen mit der praktischen Anwendung eines solchen "Computer-Stiftes" bilden den Hauptteil.

  9. Tips for Traveling with HomePEN

    Science.gov (United States)

    ... Keep Private Resources: Travel Tips Share | Tips for Traveling with HomePEN A little preparation can go a ... on your Behalf (12/2010) Other Articles on Travel TSA Program Aims to Help Elderly, Disabled, Sick ...

  10. Runs 800, 813, 842 and physics runs from 18.1.77 to 21.5.77, Development of a new set-up for working line measurements including a Fast Fourier Transform Spectrum Analyser and using weak beam excitiation with broad-band noise

    CERN Document Server

    Borer, J

    1977-01-01

    Runs 800, 813, 842 and physics runs from 18.1.77 to 21.5.77, Development of a new set-up for working line measurements including a Fast Fourier Transform Spectrum Analyser and using weak beam excitiation with broad-band noise

  11. Pen- Name in Persian and Arabic Poetry

    Directory of Open Access Journals (Sweden)

    Ebrahim Khodayar

    2012-04-01

    Full Text Available Abstract Pen-name (Takhalloss is one of the main features of Persian poetry. It has been a matter of concern among many of Persian language geography poets in the orient at least up to the Mashrouteh era. Pen-name has been promoted among the other Muslim nations throuph Persian poetry. Although it is not as famous in the Arab nations as in the Persian speaking nations, it is known as “Alqab-o-shoara” among the Arab nations and, through this way, it has affected the poetrical wealth of the Arabic poets.   The Present paper, using description-analystic approach, compares the pen-names of Persian and Arabic poets under the title of “pen-names” and investigates their features in both cultures. The main research question is: What are the similarities and differences of poetic-names, in Persian and Arabic poets in terms of the type of name, position and importance? The results showed that Pseudonym by its amazing expansion in Persian poetry has also influenced Arabic poetry. In addition to the factors affecting in the choice of pen-names (like pseudonym, pen-name, nickname..., sometimes such external factors as events, commends, community benefactors and climate, as well as internal factors including the poets’ inner beliefs are associated too. .

  12. Understanding the Dynamics of the February-April 2007 Eruptions of the Piton de la Fournaise and the Related Caldera Collapse from a Single Very Broad-band Seismic Station

    Science.gov (United States)

    Fontaine, F. R.; Roult, G. C.; Michon, L.; Barruol, G.; Ferrazzini, V.; di Muro, A.; Reymond, D.; Peltier, A.; Staudacher, T.

    2013-12-01

    Seismic records from the RER very broad-band seismic station (La Réunion Island) belonging to the GEOSCOPE network are investigated to understand the eruptive succession (February to May) of Piton de la Fournaise and the caldera collapse episode of April 2007. Data first indicate that the short-lived, small volume, summit eruption of February 18 occurred during a phase of continuous inflation initiated in end of January 2007. Inflation decelerated around 2 weeks before a second short-lived small volume eruption on March 30-31 on the SE flank, which was coeval with a sudden, large deflation of the edifice. Deflation rate, which was stabilized at a relatively low level, increased anew on April 1 while no magma was emitted, followed on April 2 by a distant and one of the most voluminous eruptions of the last two centuries at La Réunion Island. The RER station shows that very long period (VLP) and ultra long period (ULP) events developed during this period. Seven ULP events preceded the caldera collapse and 48 ones occurred during the caldera collapse over 9 days, most of which during the first 30 hours. A thorough examination of the seismic signal corrected from the tide effects shows that each collapse event was coeval with VLP and ULP signals. Each repeating individual collapse showed similar ULP and VLP signals characterized by periods of ~ 500 s and ~ 7 s, respectively. Polarization measurements (back-azimuth) of the ULP clearly point toward a source located beneath the Dolomieu crater. The strikingly constant duration of the VLP signals (around 20 s) related to the collapse events and occurring before the collapse initiation suggests a physical control of the volcanic edifice. Waveforms and spectrograms of the various caldera collapse events show very homogeneous patterns, suggesting a similar and repeating volcano-tectonic process for the formation of the VLP signals events. Although tilt may be responsible of part of the ULP signals observed during the

  13. Comparison of collision-induced dissociation and electron-induced dissociation of phillyrin using FT-ICR MS.

    Science.gov (United States)

    Lin, Zhenguang; Lin, Zhiwei; Mu, Yingdi; Yan, Dong

    2016-10-01

    Electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry using collision-induced dissociation (CID) and electron capture dissociation (ECD) at high mass resolution was first applied to investigate the characteristic fragment ions of phillyrin. The CID experimental results demonstrated the elemental composition of fragment ions unambiguously, so a reasonable fragmentation pathway of phillyrin was proposed. The ECD fragmentation mechanism was believed to be fundamentally different from the CID method. ECD could be used not only in the biological field but also as a powerful complement to the structural identification of small molecular compounds. The characteristic fragmentation pathways were helpful in analyzing and interpreting the stability and property of the parent ion. PMID:27258687

  14. High mass accuracy and high mass resolving power FT-ICR secondary ion mass spectrometry for biological tissue imaging

    NARCIS (Netherlands)

    Smith, D.F.; Kiss, A.; Leach, F.E.; Robinson, E.W.; Paša-Tolić, L.; Heeren, R.M.A.

    2013-01-01

    Biological tissue imaging by secondary ion mass spectrometry has seen rapid development with the commercial availability of polyatomic primary ion sources. Endogenous lipids and other small bio-molecules can now be routinely mapped on the sub-micrometer scale. Such experiments are typically performe

  15. Mass Recalibration of FT-ICR Mass Spectrometry Imaging Data Using the Average Frequency Shift of Ambient Ions

    Science.gov (United States)

    Barry, Jeremy A.; Robichaud, Guillaume; Muddiman, David C.

    2013-07-01

    Achieving and maintaining high mass measurement accuracy (MMA) throughout a mass spectrometry imaging (MSI) experiment is vital to the identification of the observed ions. However, when using FTMS instruments, fluctuations in the total ion abundance at each pixel due to inherent biological variation in the tissue section can introduce space charge effects that systematically shift the observed mass. Herein we apply a recalibration based on the observed cyclotron frequency shift of ions found in the ambient laboratory environment, polydimethylcyclosiloxanes (PDMS). This calibration method is capable of achieving part per billion (ppb) mass accuracy with relatively high precision for an infrared matrix-assisted laser desorption electrospray ionization (IR-MALDESI) MSI dataset. Comparisons with previously published mass calibration approaches are also presented.

  16. 长线缆宽带瞬态脉冲骚扰的传播特性分析%Propagation Characteristics of Broad Band Transient Pulse disturbance in Long Cables

    Institute of Scientific and Technical Information of China (English)

    冯德旺

    2012-01-01

    In order to solve the problem of dispersion transmission line power, Fourier sine series was used to represent electrical fast transient/burst (EFT/B). The RLCG models of twistedpair, single-line, double-line, and coaxial-cable were constructed based on the transmission line theory. Furthermore, with an application of superposition theorem, the propagation characteristics of broad band disturbance in long cables were analyzed. The results show that the disturbance voltage polarity and peak value continually changed with the increase of propagation distance. Twisted-pair and double-line had natural restrain function for EFT/B disturbance propagation in them since their voltages all attenuated to zero in load end of lkm. The disturbance voltage of coaxial-cable was the lowest in short distance, and its peak value fluctuated between positive and negative polarity in long distance. So, coaxial-cable was easily influenced by EFT/B. The disturbance voltage of single-line produced smart oscillation with the increase of propagation distance, and occurred 2. 5 times as high as EFT/B peak value in open-circuit. Finally, common mode interference was confirmed as the main form of EFT/B.%将电快速瞬变脉冲群(EFT/B)展开为傅里叶正弦级数,解决了色散传输线的激励加载问题.建立双绞线、单导线、双导线和同轴电缆的传输线模型,采用叠加原理分析宽带骚扰的传播特性,结果表明:骚扰电压极性会随着传播距离增大而不断转换,电压峰值在正负极性间呈振荡变化.双绞线和双导线对骚扰的传播具有自然抑制作用,长度为1 km时负载端的骚扰电压已衰减为0;同轴电缆在距离较短时骚扰电压峰值最低,距离较长时电压峰值会产生波动,带负载时正反向电压峰值都很大,长距离传输信号易受EFT/B的影响;单导线骚扰电压振荡最明显,且负载开路时会产生叠加效应,电压峰值最大可达激励源电压峰值的2.5倍,对地共模干扰是EFT/B的主要形式.

  17. An evaluation of prefilled insulin pens: a focus on the Next Generation FlexPen®

    Directory of Open Access Journals (Sweden)

    Estella M Davis

    2010-08-01

    Full Text Available Estella M Davis, Emily L Sexson, Mikayla L Spangler, Pamela A ForalDepartment of Pharmacy Practice, Creighton University School of Pharmacy and Health Professions, Omaha, Nebraska, USAAbstract: Insulin pen delivery systems are preferred by patients over the traditional vial and syringe method for insulin delivery because they are simple and easy to use, improve confidence in dosing insulin, and have less interference with activities and improved discretion with use. Insulin manufacturers have made numerous improvements to their first marketed pen devices and are now introducing their next generation of devices. Design modifications to the newest generation of prefilled insulin pen devices are intended to improve the ease of use and safety and continue to positively impact adherence to insulin. This review focuses on the Next Generation FlexPen® with regard to design considerations to reduce injection force, improve accuracy and ease of use, and evaluate the preference of patient and health-care provider compared with other disposable, prefilled insulin pen devices.Keywords: diabetes, dose accuracy, injection force, patient preference, insulin pen device

  18. Damping effects in Penning trap mass spectrometry

    CERN Document Server

    George, S; Kowalska, M; Dworschak, M; Neidherr, D; Blaum, K; Schweikhard, L; Ramirez, E M; Breitenfeldt, M; Kretzschmar, M; Herfurth, F; Schwarz, S; Herlert, A

    2011-01-01

    Collisions of ions with residual gas atoms in a Penning trap can have a strong influence on the trajectories of the ions, depending on the atom species and the gas pressure. We report on investigations of damping effects in time-of-flight ion-cyclotron resonance mass spectrometry with the Penning trap mass spectrometers ISOLTRAP at ISOLDE/CERN (Geneva, Switzerland) and SHIPTRAP at GSI (Darmstadt, Germany). The work focuses on the interconversion of the magnetron and cyclotron motional modes, in particular the modification of the resonance profiles for quadrupolar excitation due to the damping effect of the residual gas. Extensive experiments have been performed with standard and Ramsey excitation schemes. The results are in good agreement with predictions obtained by analytical continuation of the formulae for the undamped case.

  19. Nonlinear PIC simulation in a Penning trap

    Science.gov (United States)

    Lapenta, G.; Delzanno, G. L.; Finn, J. M.

    2002-01-01

    We study the nonlinear dynamics of a Penning trap plasma, including the effect of the finite length and end curvature of the plasma column. A new cylindrical PIC code, called KANDINSKY, has been implemented by using a new interpolation scheme. The principal idea is to calculate the volume of each cell from a particle volume, in the same manner as it is done for the cell charge. With this new method, the density is conserved along streamlines and artificial sources of compressibility are avoided. The code has been validated with a reference Eulerian fluid code. We compare the dynamics of three different models: a model with compression effects, the standard Euler model and a geophysical fluid dynamics model. The results of our investigation prove that Penning traps can really be used to simulate geophysical fluids.

  20. Extreme-field physics in Penning traps

    Energy Technology Data Exchange (ETDEWEB)

    Vogel, M., E-mail: m.vogel@gsi.de [GSI Helmholtzzentrum für Schwerionenforschung (Germany); Birkl, G. [TU Darmstadt, Institut für Angewandte Physik (Germany); Ebrahimi, M. S.; Lindenfels, D. von [GSI Helmholtzzentrum für Schwerionenforschung (Germany); Martin, A. [TU Darmstadt, Institut für Angewandte Physik (Germany); Paulus, G. G. [IOQ, Universität Jena (Germany); Quint, W. [GSI Helmholtzzentrum für Schwerionenforschung (Germany); Ringleb, S. [IOQ, Universität Jena (Germany); Stöhlker, Th.; Wiesel, M. [GSI Helmholtzzentrum für Schwerionenforschung (Germany)

    2015-11-15

    We present two Penning trap experiments concerned with different aspects of the physics of extreme electromagnetic fields, the ARTEMIS experiment designed for bound-electron magnetic moment measurements in the presence of the extremely strong fields close to the nucleus of highly charged ions, and the HILITE experiment, in which well-defined ion targets are to be subjected to high-intensity laser fields.

  1. Maximum Likelihood Analysis in the PEN Experiment

    Science.gov (United States)

    Lehman, Martin

    2013-10-01

    The experimental determination of the π+ -->e+ ν (γ) decay branching ratio currently provides the most accurate test of lepton universality. The PEN experiment at PSI, Switzerland, aims to improve the present world average experimental precision of 3 . 3 ×10-3 to 5 ×10-4 using a stopped beam approach. During runs in 2008-10, PEN has acquired over 2 ×107 πe 2 events. The experiment includes active beam detectors (degrader, mini TPC, target), central MWPC tracking with plastic scintillator hodoscopes, and a spherical pure CsI electromagnetic shower calorimeter. The final branching ratio will be calculated using a maximum likelihood analysis. This analysis assigns each event a probability for 5 processes (π+ -->e+ ν , π+ -->μ+ ν , decay-in-flight, pile-up, and hadronic events) using Monte Carlo verified probability distribution functions of our observables (energies, times, etc). A progress report on the PEN maximum likelihood analysis will be presented. Work supported by NSF grant PHY-0970013.

  2. Usability of the Stylus Pen in Mobile Electronic Documentation

    Directory of Open Access Journals (Sweden)

    Eunil Park

    2015-11-01

    Full Text Available Stylus pens are often used with mobile information devices. However, few studies have examined the stylus’ simple movements because the technical expertise to support documentation with stylus pens has not been developed. This study examined the usability of stylus pens in authentic documentation tasks, including three main tasks (sentence, table, and paragraph making with two types of styluses (touchsmart stylus and mobile stylus and a traditional pen. The statistical results showed that participants preferred the traditional pen in all criteria. Because of inconvenient hand movements, the mobile stylus was the least preferred on every task. Mobility does not provide any advantage in using the stylus. In addition, the study also found inconvenient hand support using a stylus and different feedback between a stylus and a traditional pen.

  3. Calibrating pen dosimeters with and without a phantom

    Energy Technology Data Exchange (ETDEWEB)

    Nonato, Fernanda B.C.; Cescon, Claudinei T.; Caldas, Linda V.E., E-mail: fbnonato@ipen.b, E-mail: ctcescon@ipen.b, E-mail: lcaldas@ipen.b [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2011-07-01

    Thirty one direct reading dosimeters (pen dosimeters) were calibrated and tested in standard beams of gamma radiation, with and without the use of a phantom. The calibration was performed with a Co-60 source and tested with a Cs-137 source. The dose-response curves of the pen dosimeters and their calibration factors for a Co-60 source, with and without the use of a phantom were obtained. The results show the need to calibrate the pen dosimeters with a phantom. (author)

  4. Coefficient of variation and Power Pen's parade computation

    OpenAIRE

    Sadefo Kamdem, Jules

    2011-01-01

    Under the the assumption that income y is a power function of its rank among n individuals, we approximate the coefficient of variation and gini index as functions of the power degree of the Pen's parade. Reciprocally, for a given coefficient of variation or gini index, we propose the analytic expression of the degree of the power Pen's parade; we can then compute the Pen's parade.

  5. Simulation of the Lanzhou Penning Trap LPT

    Institute of Scientific and Technical Information of China (English)

    HUANG Wen-Xue; WANG Jun-Ying; WANG Yue; TIAN Yu-Lin; ZHU Zhi-Chao; XU Hu-Shan; XIAO Guo-Qing

    2009-01-01

    The LPT (Lanzhou Penning Trap) is under construction and its task is to perform direct mass measurement of fusion-evaporation residues and if possible for heavy isotopes. Detailed simulations have been done for a good understanding to the ion's movement and mechanics in the trap. The optimization of the LPT is also performed based on the simulation. With a scale of 0.5 mm per grid used in the simulation and many other limitations a highest mass resolution has been achieved to be 1.9 × 10-5. An unexpected behaviour in the simulation related to magnetron motion has been found.

  6. French Pen Pals Made Easy KS3

    CERN Document Server

    Leleu, Sinéad

    2010-01-01

    French Pen Pals Made Easy provides an easy way for pupils to communicate in French with other French speakers. It contains fill-in-the-gap letters, so even pupils just beginning to learn French can have the satisfaction of being able to communicate effectively in French. The format is ideal for non-specialist teachers as it does not require fluency and little or no preparation is required. English translations of the letters are included, as are lists of vocabulary, key grammar points and exten

  7. Comparing soil and pond ash feedlot pen surfaces for environmental management

    Science.gov (United States)

    Removing manure and replacing soil to maintain pen surfaces is expensive. Pond ash (PA), a coal-fired electrical generation by-product, has good support qualities. A study was conducted comparing the performance of pond ash (PA) surfaced pens with soil surface (SS) pens. Four pens of an eight pen se...

  8. Penning trap for isobaric mass separation at IGISOL

    CERN Document Server

    Kolhinen, V; Hakala, J; Jokinen, A; Kopecky, S; Rinta-Antila, S; Szerypo, J; Äystö, J

    2003-01-01

    A cylindrical Penning trap has been built at the ion guide isotope separator facility IGISOL of the University of Jyvaeskylae. The main goal of the Penning trap application is to purify low-energy radioactive ion beams. The aim is to make isobarically pure beams. The technical description is presented.

  9. Penning trap for isobaric mass separation at IGISOL

    Energy Technology Data Exchange (ETDEWEB)

    Kolhinen, V.S. E-mail: veli.kolhinen@phys.jyu.fi; Eronen, T.; Hakala, J.; Jokinen, A.; Kopecky, S.; Rinta-Antila, S.; Szerypo, J.; Aeystoe, J

    2003-05-01

    A cylindrical Penning trap has been built at the ion guide isotope separator facility IGISOL of the University of Jyvaeskylae. The main goal of the Penning trap application is to purify low-energy radioactive ion beams. The aim is to make isobarically pure beams. The technical description is presented.

  10. 9 CFR 313.1 - Livestock pens, driveways and ramps.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Livestock pens, driveways and ramps. 313.1 Section 313.1 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF... INSPECTION AND CERTIFICATION HUMANE SLAUGHTER OF LIVESTOCK § 313.1 Livestock pens, driveways and ramps....

  11. Dosing Accuracy of Insulin Pens Versus Conventional Syringes and Vials

    NARCIS (Netherlands)

    Y.M. Luijf; J.H. Devries

    2010-01-01

    Pen injection devices have acquired a pivotal role in insulin delivery, surpassing the use of conventional insulin syringes in many parts of the world. In this review we sought to determine differences in dosing accuracy between insulin pens and conventional syringes and vials, also touching on pati

  12. Parallel Processing of Broad-Band PPM Signals

    Science.gov (United States)

    Gray, Andrew; Kang, Edward; Lay, Norman; Vilnrotter, Victor; Srinivasan, Meera; Lee, Clement

    2010-01-01

    A parallel-processing algorithm and a hardware architecture to implement the algorithm have been devised for timeslot synchronization in the reception of pulse-position-modulated (PPM) optical or radio signals. As in the cases of some prior algorithms and architectures for parallel, discrete-time, digital processing of signals other than PPM, an incoming broadband signal is divided into multiple parallel narrower-band signals by means of sub-sampling and filtering. The number of parallel streams is chosen so that the frequency content of the narrower-band signals is low enough to enable processing by relatively-low speed complementary metal oxide semiconductor (CMOS) electronic circuitry. The algorithm and architecture are intended to satisfy requirements for time-varying time-slot synchronization and post-detection filtering, with correction of timing errors independent of estimation of timing errors. They are also intended to afford flexibility for dynamic reconfiguration and upgrading. The architecture is implemented in a reconfigurable CMOS processor in the form of a field-programmable gate array. The algorithm and its hardware implementation incorporate three separate time-varying filter banks for three distinct functions: correction of sub-sample timing errors, post-detection filtering, and post-detection estimation of timing errors. The design of the filter bank for correction of timing errors, the method of estimating timing errors, and the design of a feedback-loop filter are governed by a host of parameters, the most critical one, with regard to processing very broadband signals with CMOS hardware, being the number of parallel streams (equivalently, the rate-reduction parameter).

  13. High Reflectivity, Broad-Band Silver Coating Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Silver coatings for optics greater than 2-meters in diameter are sought by NASA for future space telescope systems. In the Phase I research, Surface Optics...

  14. Ultra-broad band supercontinuum produced by terawatt femtosecond laser

    Institute of Scientific and Technical Information of China (English)

    张伟力; 王清月; 邢岐荣; 柴路; K.M.Yoo

    1997-01-01

    The characteristics of supercontinuum produced by high-intensity femtosecond pulses were investigated under different interaction lengths, various pump intensities, different pump wavelengths at the fundamental 800 nm and its second-harmonic 400 nm. High transfer-efficiency supercontinuum with flat-top in liquid media was produced. As the main nonlinear mechanisms, the effects of self-phase modulation (SPM) and four-photon parametric emission were also investigated.

  15. Muscle Oxygenation During Running Assessed by Broad Band NIRS.

    Science.gov (United States)

    Steimers, A; Vafiadou, M; Koukourakis, G; Geraskin, D; Neary, P; Kohl-Bareis, M

    2016-01-01

    We used spatially resolved near-infrared spectroscopy (SRS-NIRS) to assess calf and thigh muscle oxygenation during running on a motor-driven treadmill. Two protocols were used: An incremental speed protocol was performed in 5-min stages, while a pacing paradigm modulated the step frequency (2.3 Hz [SLow]; 3.3 Hz [SHigh]) during a constant velocity for 2 min each. A SRS-NIRS broadband system was used to measure total haemoglobin concentration and oxygen saturation (SO2). An accelerometer was placed on the hip joints to measure limb acceleration through the experiment. The data showed that the calf desaturated to a significantly lower level than the thigh. During the pacing protocol, SO2 was significantly different between the high and low step frequencies. Additionally, physiological data as measured by spirometry were different between the SLow vs. SHigh pacing trials. Significant differences in VO2 at the same workload (speed) indicate alterations in mechanical efficiency. These data suggest that SRS broadband NIRS can be used to discern small changes in muscle oxygenation, making this device useful for metabolic exercise studies in addition to spirometry and movement monitoring by accelerometers. PMID:26782193

  16. Broad-Band EUV Multilayer Coatings For Solar Physics Project

    Data.gov (United States)

    National Aeronautics and Space Administration — We propose to develop and commercialize a new class of aperiodic multilayer coating that is designed to provide high normal-incidence reflectance over a wide...

  17. Free space optical networks for ultra-broad band services

    CERN Document Server

    Kartalopoulos, Stamatios V

    2011-01-01

    "Free Space Optical Network is a next generation communication network which uses optical waves instead of microwaves, potentially offering faster communication with ultra band width, meaning more complex communication services can be simultaneously offered. This book describes the network concepts in simple language starting with point-to-point free space optics basics and discusses networking, interoperability with existing communication network, and security. An ideal resource for communication professionals just entering the free space optical communication field and graduate students majoring in optical communications"--Provided by publisher.

  18. Ultra-broad band absorber made by tungsten and aluminium

    Science.gov (United States)

    Wang, Wei; Zhao, Ding; Li, Qiang; Qiu, Min

    2016-01-01

    A broadband absorber comprising tungsten cubic arrays, a alumina layer and a tungsten film, is numerically and experimentally investigated, which exhibits near-unity absorption of visible and near-infrared light from 400 nm to 1150 nm. Benefiting from high melting points of tungsten and alumina, this device has great application potential in solar cells and thermal emission.

  19. Computer-aided design of broad band reflection type amplifiers

    DEFF Research Database (Denmark)

    Hammershaimb, Edgar; Jeppesen, Palle; Schjær-Jacobsen, Hans

    1974-01-01

    Microwave negative resistance reflection type amplifiers using stable transferred electron devices (TED's) are optimized by numerical optimization techniques programmed for an interactive graphic datascreen. The small signal impedance of packaged TED's is measured on an automatic network analyzer....... At the same time the impedance of unpackaged devices are obtained by on-line correction for the package parasitics. The microwave circuit chosen is a multiple slug coaxial cavity, that is modelled by sections of lossy transmission lines including step susceptances. The measured small signal impedance...

  20. High Reflectivity, Broad-Band Silver Coating Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Future space telescopes such as the Super Nova Acceleration Probe (SNAP) require exceptionally reflective coatings applied to mirrors several meters in diameter. In...

  1. Broad Band Antireflection Coatings for Silicon and Germanium Substrates.

    Science.gov (United States)

    Bezuidenhout, Dirk Francois

    Infrared antireflection coatings for silicon and germanium substrates and some of the associated problems are addressed in this thesis. One of the first problems identified and investigated was that of the adhesion of ZnS films to germanium substrates. The cleaning of the Ge discs was evaluated by means of Auger spectroscopy. The main contaminant species found were carbon, oxygen and in the case of germanium substrates sulphur. No sulphur was found on silicon substrates. A wash in a series of organic solutions followed by a bake inside the vacuum chamber lead to much improved though still not acceptable adhesion of ZnS films to germanium substrates. The influence of a contact layer between the substrate and ZnS was investigated. Firstly, metal contact layers (Ni, Cr, Cu) were tried to improve the adhesion of the ZnS films. These samples (germanium-metal-zinc sulphide) were annealed in air in order to transfer the germanium -metal film to a germanide region and thus high optical transmission at long wave-lengths. Slight absorption still results even after the annealing of these samples. A dielectric material, Y_2O_3 , was therefore tested replacing the metal films. The system Ge-Y_2O_3 -ZnS in conjunction with an organic wash and vacuum bake lead to excellent adhesion of the ZnS layers to the germanium substrates. The next problem area addressed was that of a low refractive index material replacement for ThF _4. Four materials were investigated, i.e. ZnS, PbF_2, Y_2O _3 and YF_3. The refractive indices found for these compounds in thin film form at a wavelength of 10 μm is 2,18 for ZnS, 1,7 for PbF_2, 1,42 for Y_2O_3 and 1,3 for YF_3. From these results YF_3 was chosen as low refractive index material in the coating designs. Multi-layer coatings incorporating ZnS, Ge and YF_3 films were designed and evaporated. Measured reflectance values below 0,2% were obtained from 9 μm to 11 mum. These systems were stable and robust. Finally, a silicon ball lens was antireflected utilizing an oxidation process. This method led to a uniformly thick layer across the complete surface of the lens.

  2. Broad Band Properties of the BAT Selected AGN

    Science.gov (United States)

    Mushotzky, Richard; Winter, Lisa; Tueller, Jack

    2008-01-01

    I will present the x-ray spectral properties of approx.150 BAT selected ACN focusing on the issues of spectral complexity, x-ray absorption and its distribution and that contribution of sources to the x-ray background. If time permits we will also present the nature of the host galaxies of the ACN and their relationship to merger candidates.

  3. Penning trap with an inclined magnetic field

    Science.gov (United States)

    Yaremko, Yurij; Przybylska, Maria; Maciejewski, Andrzej J.

    2016-08-01

    A modified Penning trap with a spatially uniform magnetic field B inclined with respect to the axis of rotational symmetry of the electrodes is considered. The inclination angle can be arbitrary. Canonical transformation of phase variables transforming the Hamiltonian of the considered system into a sum of three uncoupled harmonic oscillators is found. We determine the region of stability in space of two parameters controlling the dynamics: the trapping parameter κ and the squared sine of the inclination angle ϑ 0 . If the angle ϑ 0 is smaller than 54°, a charge occupies a finite spatial volume within the processing chamber. A rigid hierarchy of trapping frequencies is broken if B is inclined at the critical angle: the magnetron frequency reaches the modified cyclotron frequency while the axial frequency exceeds them. Apart from this resonance, we reveal the family of resonant curves in the region of stability. In the relativistic regime, the system is not linear. We show that it is not integrable in the Liouville sense. The averaging over the fast variable allows to reduce the system to two degrees of freedom. An analysis of the Poincaré cross-sections of the averaged systems shows the regions of effective stability of the trap.

  4. Doctor--how do I use my EpiPen?

    Science.gov (United States)

    Mehr, Sam; Robinson, Marnie; Tang, Mimi

    2007-08-01

    Parents and children who have been prescribed an Epipen are often unable to demonstrate its correct administration. One contributory factor may be that doctors are unfamiliar with the EpiPen and are unable to demonstrate the correct administration of the pen to the family. The aim of this study was to determine the rate of correct EpiPen demonstration by junior and Senior Medical Staff at a major tertiary paediatric Hospital. Junior and Senior medical staff were scored on their ability to correctly use the EpiPen trainer. A 6 step scoring system was used. One-hundred doctors were recruited (Residents n = 31, Senior Residents n = 39, Fellow/Consultants n = 30). Junior and Senior Medical staff had similar scores for EpiPen demonstration, the number that needed to read the EpiPen instructions prior to use and the frequancy of accidental self-injection into the thumb. Only two doctors (2%) demonstrated all 6 administration steps correctly. The most frequent errors made were not holding the pen in place for >5 seconds (57%), failure to apply pressure to activate (21%), and self-injection into the thumb (16%). Ninety five doctors needed to read the instructions, and of these, only 39 (41%) then proceeded to correctly demonstrate the remaining 5 steps. Forty-five doctors had previously dispensed an EpiPen, but only three demonstrated its use to parents/children with a trainer. The majority of doctors do not know how to use an Epipen and are unable to provide appropriate education to parents/children. In 37% of cases, the demonstration would not have delivered adrenaline to a patient.

  5. Analysis of roller pen inks by capillary zone electrophoresis

    Institute of Scientific and Technical Information of China (English)

    ZHAO Pengcheng; WANG Yanji; XU Yuanyuan; YAO Lijuan

    2007-01-01

    The analysis of roller pen inks has become more and more important in fraudulent document examination because of the extensive use of roller pens in financial documents.Capillary electrophoresis with powerful resolution was applied for the analysis of roller pen inks.The experiment focused on the optimization of the separation of the extract from commercially available roller pen entries.A better separation electropherogram was obtained when a 20 mM borate buffer at pH 8.5 and a fused silica capillary with an inner diameter of 100 μm with a total length of 47 (40 cm to the detector window)were used.Five inks from roller pens of different manufacturers and countries were analyzed,and their electropherograms showed that most patterns are distinctly different from each other.Capillary with inner diameter of 100 μm increased the intensity of determination;therefore,color dyes were identified in the visible range and were able to provide more information for comparing types of roller pen inks.

  6. A motion control function evaluation system employing a pen tablet.

    Science.gov (United States)

    Iwamoto, Junichi; Yonezawa, Yoshiharu; Maki, Hiromichi; Ogawa, Hidekuni; Ninomiya, Ishio; Sata, Koji; Nomura, Naonobu; Hamada, Shingo; Hahn, Allen W; Caldwell, W Morton

    2005-01-01

    We have developed a new pen tablet based system for evaluation of hand motion control function as influenced by brain disease. The system consists of a laptop computer and a pen tablet data entry device. The pen tablet is placed in front of the subject who is instructed to tap the pen at a constant location. When the subject taps the pen, the tablet transfers the pen position to the laptop computer. The computer then saves the tap position, along with the time elapsed between each tap. The subject is instructed to tap 50 times with each hand with the eyes closed. The absolute distance moved between each two successive tap positions is detected. Tapping period, total tapping time and total distance moved are also calculated. Measurements were performed on ten normal subjects and three subjects with cerebral infarction. The results indicate that cerebral infarction subjects' average total tap point distance moved and absolute distance moved are greater than in the normal subjects. Conversely, all subjects in both groups produced only normal variations in tapping period and total tapping time. Our system can therefore quantitatively evaluate hand motion control function by the total and absolute distance moved. PMID:15850121

  7. Picking among pen-reared quail

    Science.gov (United States)

    Nestler, R.B.; Coburn, D.R.; Titus, H.W.

    1945-01-01

    During five years (1939-43) of nutritional research on pen-reared bobwhite quail at the Patuxent Research Refuge, Bowie, Maryland, observations on picking among birds of all ages showed the following results: 1. Picking occurred on all grains tested: corn, wheat, oats, oat groats, barley, millet, buckwheat, kaffir, and mixtures of cereals. The lowest incidence was with buckwheat as the sole grain in a growing diet....2. Picking occurred on all levels of fiber from one to 11per cent in a growing diet....3. Picking occurred on various grinds of corn, barley, and oats, but was least when these cereals were ground in a hammer mill with 3/32 inch mesh screen....4. The incidence was as high on diets containing animal protein as on those containing no animal protein. ....5. After picking began, the addition of one or two per cent of salt to the diet for several days was effective, in many instances, in checking the disorder. Results at the Refuge and the answers to questionnaires from 222 private propagators of gamebirds showed that in two-thirds. of the cases, treatment with an increased quantity of salt successfully stopped the trouble. As a preventative, however, salt was of little value. Picking occurred on both low and high levels of salt.....6. Supplementing the regular diet with certain feed concentrates such as fishmeal, soybean oil meal, liver meal, or chopped greens offered in a separate feeder for a day or two, was as efficacious as the addition of salt.....7. More picking occurred among quail chicks on a 22 per cent level of protein than on higher levels.....8. There was less picking on diets relished by the birds than on those seemingly unpalatable.....9. There was no correlation. between the amount of floor space per chick and the incidence of picking.....10. Increasing the feeding and drinking space seemed to have a marked beneficial effect.....11. Some adult birds on wire floors resorted to self-picking of their feet after the toes were frost-bitten.

  8. PEN as substrate for new solar cell technologies

    Energy Technology Data Exchange (ETDEWEB)

    Fonrodona, M.; Escarre, J.; Villar, F.; Soler, D.; Asensi, J.M.; Bertomeu, J.; Andreu, J. [CeRMAE-Departament de Fisica Aplicada i Optica, Universitat de Barcelona, Marti i Franques 1, 08028 Barcelona, Catalonia (Spain)

    2005-10-14

    The possible use of polyethylene naphthalate as substrate for low-temperature deposited solar cells has been studied in this paper. The transparency of this polymer makes it a candidate to be used in both substrate and superstrate configurations. ZnO:Al has been deposited at room temperature on top of PEN. The resulting structure PEN/ZnO:Al presented good optical and electrical properties. PEN has been successfully textured (nanometer and micrometer random roughness) using hot-embossing lithography. Reflector structures have been built depositing Ag and ZnO:Al on top of the stamped polymer. The deposition of these layers did not affect the final roughness of the whole. The reflector structure has been morphologically and optically analysed to verify its suitability to be used in solar cells.

  9. III. Penning ionization, associative ionization and chemi-ionization processes

    International Nuclear Information System (INIS)

    Physical mechanisms of three important ionization processes in a cold plasma and the methods of their experimental study are discussed. An apparatus for the investigation of the Penning ionization using ionization processes of long lived metastable rare gas atoms is described. Methods of determining interaction energies and ionization rates from the measured energy spectra of the originating electrons are described and illustrated by several examples. Typical associative ionization processes are listed and the ionization rates are compared with those of the Penning ionization. Interactions with short-lived excited particles and the transfer of excitation without ionization are discussed. (J.U.)

  10. Scaled, circular-emitter Penning SPS for intense H- beams

    International Nuclear Information System (INIS)

    The Los Alamos versions of the Penning Surface-Plasma Source (SPS) routinely generate H- ion beams with pulsed currents over 100 mA. However, these sources employ geometries that result in the extraction of slit beams (0.5 x 10 mm2). Our modeling with the SNOW code indicates that the beam from a 5.4-mm-diam circular emitter will have lower emittance and divergence for transport to and injection into our radio-frequency quadrupole (RFQ) accelerator. This paper describes a newly constructed Penning SPS that has most of its discharge chamber dimensions scaled up by a factor of 4 to accommodate this circular emitter

  11. Lorentz-violating spinor electrodynamics and Penning traps

    CERN Document Server

    Ding, Yunhua

    2016-01-01

    The prospects are explored for testing Lorentz- and CPT-violating quantum electrodynamics in experiments with Penning traps. We present the Lagrange density of Lorentz-violating spinor electrodynamics with operators of mass dimensions up to six, and we discuss some of its properties. The theory is used to derive Lorentz- and CPT-violating perturbative shifts of the energy levels of a particle confined to a Penning trap. Observable signals are discussed for trapped electrons, positrons, protons, and antiprotons. Existing experimental measurements on anomaly frequencies are used to extract new or improved bounds on numerous coefficients for Lorentz and CPT violation, using sidereal variations of observables and comparisons between particles and antiparticles.

  12. Identification of Potential Glycoprotein Biomarkers in Estrogen Receptor Positive (ER+ and Negative (ER- Human Breast Cancer Tissues by LC-LTQ/FT-ICR Mass Spectrometry

    Directory of Open Access Journals (Sweden)

    Suzan M. Semaan, Xu Wang, Alan G. Marshall, Qing-Xiang Amy Sang

    2012-01-01

    Full Text Available Breast cancer is the second most fatal cancer in American women. To increase the life expectancy of patients with breast cancer new diagnostic and prognostic biomarkers and drug targets must be identified. A change in the glycosylation on a glycoprotein often causes a change in the function of that glycoprotein; such a phenomenon is correlated with cancerous transformation. Thus, glycoproteins in human breast cancer estrogen receptor positive (ER+ tissues and those in the more advanced stage of breast cancer, estrogen receptor negative (ER- tissues, were compared. Glycoproteins showing differences in glycosylation were examined by 2-dimensional gel electrophoresis with double staining (glyco- and total protein staining and identified by reversed-phase nano-liquid chromatography coupled with a hybrid linear quadrupole ion trap/ Fourier transform ion cyclotron resonance mass spectrometer. Among the identified glycosylated proteins are alpha 1 acid glycoprotein, alpha-1-antitrypsin, calmodulin, and superoxide dismutase mitochondrial precursor that were further verified by Western blotting for both ER+ and ER- human breast tissues. Results show the presence of a possible glycosylation difference in alpha-1-antitrypsin, a potential tumor-derived biomarker for breast cancer progression, which was expressed highest in the ER- samples.

  13. Applications of Fourier Transform Ion Cyclotron Resonance (FT-ICR) and Orbitrap Based High Resolution Mass Spectrometry in Metabolomics and Lipidomics

    Science.gov (United States)

    Ghaste, Manoj; Mistrik, Robert; Shulaev, Vladimir

    2016-01-01

    Metabolomics, along with other “omics” approaches, is rapidly becoming one of the major approaches aimed at understanding the organization and dynamics of metabolic networks. Mass spectrometry is often a technique of choice for metabolomics studies due to its high sensitivity, reproducibility and wide dynamic range. High resolution mass spectrometry (HRMS) is a widely practiced technique in analytical and bioanalytical sciences. It offers exceptionally high resolution and the highest degree of structural confirmation. Many metabolomics studies have been conducted using HRMS over the past decade. In this review, we will explore the latest developments in Fourier transform mass spectrometry (FTMS) and Orbitrap based metabolomics technology, its advantages and drawbacks for using in metabolomics and lipidomics studies, and development of novel approaches for processing HRMS data. PMID:27231903

  14. Unraveling the venom proteome of the bumblebee (Bombus terrestris) by integrating a combinatorial peptide ligand library approach with FT-ICR MS.

    Science.gov (United States)

    Van Vaerenbergh, Matthias; Debyser, Griet; Smagghe, Guy; Devreese, Bart; de Graaf, Dirk C

    2015-08-01

    Within the Apidae, the largest family of bees with over 5600 described species, the honeybee is the sole species with a well studied venom proteome. So far, only little research has focused on bumblebee venom. Recently, the genome sequence of the European large earth bumblebee (Bombus terrestris) became available and this allowed the first in-depth proteomic analysis of its venom composition. We identified 57 compounds, with 52 of them never described in bumblebee venom. Remarkably, 72% of the detected compounds were found to have a honeybee venom homolog, which reflects the similar defensive function of both venoms and the high degree of homology between both genomes. However, both venoms contain a selection of species-specific toxins, revealing distinct damaging effects that may have evolved in response to species-specific attackers. Further, this study extends the list of potential venom allergens. The availability of both the honeybee and bumblebee venom proteome may help to develop a strategy that solves the current issue of false double sensitivity in allergy diagnosis, which is caused by cross-reactivity between both venoms. A correct diagnosis is important as it is recommended to perform an immunotherapy with venom of the culprit species. PMID:26071081

  15. Gold chloride clusters with Au(III) and Au(I) probed by FT-ICR mass spectrometry and MP2 theory.

    Science.gov (United States)

    Lemke, Kono H

    2014-05-01

    Microsolvated clusters of gold chloride are probed by electrospray ionization mass spectrometry (ESI-MS) and scalar relativistic electronic structure calculations. Electrospray ionization of aqueous AuCl3 leads to mononuclear clusters of types [AuCl2](+)(H2O)n (n = 0-4), [AuOHCl](+)(H2O)n (n = 0-1) and [AuCl2](+)(HCl)2(H2O)n (n = 0-4). In addition, strong ion signals due to dinuclear [Au2Cl5-xOHx](+)(H2O)n (x = 0-1) are present in ESI mass spectra of aqueous AuCl3, with the abundance of individual dinuclear species controlled by the concentration-dependent variation of the precursor complexes [AuCl2-xOHx](+)(H2O)n and AuCl3. Equilibrium structures, energies and thermodynamic properties of mono- and dinuclear gold clusters have been predicted using MP2 and CCSD(T) theory, and these data have been applied to examine the influence of microsolvation on cluster stability. Specifically, results from CCSD(T) calculations indicate that non-covalently bound ion-neutral complexes Au(+)(Cl2)(H2O)n, with formal Au(I), are the dominant forms of mononuclear gold with n = 0-2, while higher hydrates (n > 2) are covalently bound [AuCl2](+)(H2O)n complexes in which gold exists as Au(III). MP2 calculations show that the lowest energy structure of dinuclear gold is an ion-molecule cluster [Au2Cl(Cl2)2](+) consisting of a single-bridged digold-chloronium ion bound end-on to two dichlorine ligands, with two higher energy isomers, single-bridged [Au2Cl3(Cl2)](+) and double-bridged [Au2Cl5](+) clusters. Finally, AuAu interactions in the singly-bridged clusters [Au2Cl(Cl2)2](+)(H2O)n and [Au2Cl3(Cl2)](+)(H2O)n are examined employing a wide range of computational tools, including natural bond order (NBO) analysis and localized orbital locator (LOL) profiles. PMID:24643288

  16. Testing Lorentz and CPT Symmetries in Penning Traps

    CERN Document Server

    Ding, Yunhua

    2016-01-01

    A modified Dirac equation with general Lorentz- and CPT-violating operators in the electromagnetic field is studied. Constraints on and possible sensitivities to Lorentz-violating coefficients in the nonminimal sector up to mass-dimension six can be obtained by analyzing Penning-trap results involving anomaly frequencies.

  17. Multi-pen Sketch Recognition in a Learning Environment

    Directory of Open Access Journals (Sweden)

    Liam Don

    2009-04-01

    Full Text Available Virtual physics environments are becoming increasingly popular as a teaching tool for high school level mechanical physics. While useful, these tools often offer a complex user interface, lacking the intuitive nature of the traditional whiteboard. Furthermore, the systems are often too advanced to be used by novice students for further experimentation. In this paper we describe a physics learning environment using multicolour sketch recognition techniques on digital whiteboards. The recognition system is based on a combination of Support Vector Machines and rule based methods. By assigning the various drawing modes to different physical drawing pens, we can resolve several ambiguities appearing in single pen sketching interfaces. Moreover, we argue that we can reduce the cognitive load of the user by exploiting the physical realisation of drawing modes in the form of drawing pens, instead of using textual descriptions of the modes on the screen. The system was tested using a constructive interaction method, with users completing a set task; first in a multi-pen drawing environment, and then for comparison purposes in a singlepen equivalent.

  18. Le Pen õigustas natside tegevust Prantsusmaal / Margo Pajuste

    Index Scriptorium Estoniae

    Pajuste, Margo

    2005-01-01

    Prantsuse paremäärmusliku partei juht Jean-Marie Le Pen väitis, et Saksa okupatsioon II maailmasõja ajal Prantsusmaal ei olnud eriti ebainimlik ja et kui väited massimõrvade kohta Prantsusmaal vastaksid tõele, poleks olnud vaja luua koonduslaagreid poliitvangidele. Reageeringutest Le Peni väidete kohta Prantsusmaal

  19. A Digital Library for Education: The PEN-DOR Project.

    Science.gov (United States)

    Fullerton, Karen; Greenberg, Jane; McClure, Maureen; Rasmussen, Edie; Stewart, Darin

    1999-01-01

    Describes Pen-DOR (Pennsylvania Education Network Digital Object Repository), a digital library designed to provide K-12 educators with access to multimedia resources and tools to create new lesson plans and modify existing ones via the World Wide Web. Discusses design problems of a distributed, object-oriented database architecture and describes…

  20. A Pen-Based System for the Psychiatric Emergency Room

    OpenAIRE

    Kennedy, Robert S.

    1995-01-01

    Translating paper based clinical assessment forms to computer based forms for a Psychiatric Emergency Room was facilitated by the use of a computer using Windows for Pen® system and a familiar database. Offering a smooth transition from paper to electronic forms was the primary goal for this busy metropolitan Psychiatric Emergency Room.

  1. Is the Penning Ion Trap Suitable for Quantum Computation?

    Science.gov (United States)

    Bollinger, J. J.; Kriesel, J. M.; Itano, W. M.; Mitchell, T. B.

    2001-10-01

    There is a great deal of interest in finding a physical system which can perform computations through quantum unitary operations and be scaled to large numbers of qubits. rf ion traps have been used in pioneering experiments on a few qubits. The Penning ion trap has some potential advantages compared to the rf trap. In rf traps, heating and decoherence rates of ion motional states have been observed to scale inversely with the size of the electrodes. Penning traps can have large electrodes while still retaining the large (5-10 MHz) motional frequencies required for quantum logic operations. This is because large static fields are more easily generated than large amplitude rf fields. Addressing of individual ions in the Penning trap is complicated by the plasma rotation, but should be possible with crystallized, planar plasmas controlled by a combination of rotating fields (a ``hard disk" geometry). We will discuss the pros and cons as well as some initial experiments to investigate the suitability of the Penning trap for quantum computation.

  2. Economic evaluation of the administration of follitropin-beta with a pen device.

    NARCIS (Netherlands)

    Bruynesteyn, K.; Bonsel, G.J.; Braat, D.D.M.; Fauser, B.C.J.M.; Devroey, P.; Genugten, M.L.L van

    2005-01-01

    Previous studies suggest that administration of follitropin-beta with a pen device (Puregon Pen(R)) is more convenient, less painful and 16-18% more efficient. The aim of this study was to perform an economic evaluation of the administration of follitropin-beta by this pen device against follitropin

  3. Possible contamination with clenbuterol from treated veal calves to untreated pen mates

    NARCIS (Netherlands)

    Groot, M.J.; Lasaroms, J.J.P.; Bennekom, van E.O.; Hende, van J.; Nielen, M.W.F.

    2013-01-01

    To investigate whether clenbuterol-treated calves could contaminate untreated pen mates, three animal experiments were performed. (1) One calf of a pen of five was treated with clenbuterol by injection (Ventipulmin injection, REG NL 2532, 2.5 mL/100 kg) twice a day for 10 days. (2) In two pens, one

  4. Impacts of a freedom farrowing pen design on sow behaviours and performance.

    Science.gov (United States)

    Gu, Zhaobing; Gao, Yajun; Lin, Baozhong; Zhong, Zhengze; Liu, Zuohua; Wang, Chaoyuan; Li, Baoming

    2011-12-15

    The limited space in farrowing crate imposes many challenges, such as prolonged farrowing duration and high piglet stillbirth rate. Although the features of farrowing pens compensate for the drawbacks of farrowing crates, they are associated with high piglet crushing mortality caused by the greater space afforded to sows and their rolling-over behaviour. Therefore, a freedom farrowing pen was designed to overcome the drawbacks of both farrowing crates and farrowing pens. The main features of the freedom farrowing pen are its left anti-crushing bar and detachable right anti-crushing bar on the sides of the sow lying area. It also has a 10 cm-high anti-crushing bar in the non-lying area. Eighteen healthy, multiparous Yorkshire sows (3-7 parity) were averaged and randomly assigned to farrowing crates, farrowing pens, and freedom farrowing pens to compare the effects of the farrowing systems on sow behaviour and performance. Results showed that the farrowing duration and the mean piglet birth intervals were longer for the sows in farrowing crates than for those in farrowing pens and freedom farrowing pens (P0.05). The piglet stillbirth rate was higher for the sows in farrowing crates than for those in farrowing pens and freedom farrowing pens (PCrushing mortality was higher among piglets in farrowing pens (Ppiglets in freedom farrowing pens and those in farrowing crates (P>0.05). The freedom farrowing pen and the farrowing pen allowed sows to turn around and move freely, but because of the different structures of their anti-crushing bars, the increase in sow movement did not cause higher piglet crushing mortality (P>0.05). Sows in freedom farrowing pens were found to be more protective of their piglets. PMID:21880386

  5. Penning ionization of doped helium nanodroplets following EUV excitation

    CERN Document Server

    Buchta, D; Brauer, N B; Drabbels, M; O'Keeffe, P; Devetta, M; DiFraia, M; Callegari, C; Richter, R; Coreno, M; Prince, K; Stienkemeier, F; Moshammer, R; Mudrich, M

    2013-01-01

    Helium nanodroplets are widely used as a cold, weakly interacting matrix for spectroscopy of embedded species. In this work we excite or ionize doped He droplets using synchrotron radiation and study the effect onto the dopant atoms depending on their location inside the droplets (rare gases) or outside at the droplet surface (alkali metals). Using photoelectron-photoion coincidence imaging spectroscopy at variable photon energies (20-25 eV), we compare the rates of charge-transfer to Penning ionization of the dopants in the two cases. The surprising finding is that alkali metals, in contrast to the rare gases, are efficiently Penning ionized upon excitation of the (n=2)-bands of the host droplets. This indicates rapid migration of the excitation to the droplet surface, followed by relaxation, and eventually energy transfer to the alkali dopants.

  6. Beyond the Brillouin limit with the Penning Fusion Experiment

    International Nuclear Information System (INIS)

    Several years ago, it was proposed that a dense non-neutral plasma could be produced in a Penning trap. Nonneutral plasmas have excellent confinement, and such a dense plasma might produce simultaneously high density and good confinement. Recently, this theoretical conjecture has been demonstrated in a small (3 mm radius) electron experiment, PFX (Penning Fusion Experiment). Densities up to 35 times the Brillouin density (limiting number density in a static trap) have been inferred from the observed strong (100:1) spherical focusing. Electrons are injected at low energy from a single pole of the sphere. A surprising observation is the self-organization of the system into a spherical state, which occurs precisely when the trap parameters are adjusted to produce a spherical well. This organization is caused by a bootstrapping mechanism which produces a hysteresis. Observations of energy-scattered electrons confirm the existence of a dense spherical focus. copyright 1997 American Institute of Physics

  7. Determining isotopic distributions of fission products with a penning trap

    Energy Technology Data Exchange (ETDEWEB)

    Penttilae, H.; Karvonen, P.; Eronen, T.; Elomaa, V.V.; Hager, U.; Hakala, J.; Jokinen, A.; Kankainen, A.; Moore, I.D.; Peraejaervi, K.; Rahaman, S.; Rinta-Antila, S.; Saastamoinen, A.; Sonoda, T.; Aeystoe, J. [University of Jyvaeskylae, Department of Physics, Jyvaeskylae (Finland); Rubchenya, V. [University of Jyvaeskylae, Department of Physics, Jyvaeskylae (Finland); V.G. Khlopin Radium Institute, St. Petersburg (Russian Federation)

    2010-04-15

    A novel method to determine independent yields in particle-induced fission employing the ion guide technique and ion counting after a Penning trap has been developed. The method takes advantage of the fact that a Penning trap can be used as a precision mass filter, which allows an unambiguous identification of the fission fragments. The method was tested with 25MeV and 50MeV proton-induced fission of {sup 238}U. The data is internally reproducible with an accuracy of a few per cent. A satisfactory agreement was obtained with older ion guide yield measurements in 25MeV proton-induced fission. The results for Rb and Cs yields in 50MeV proton-induced fission agree with previous measurements performed at an isotope separator equipped with a chemically selective ion source. (orig.)

  8. Translocation techniques used to establish pen farmed Alaskan reindeer

    Directory of Open Access Journals (Sweden)

    R. A. Dieterich

    1990-09-01

    Full Text Available Small herds of reindeer (Rangifer tarandus frequently have been needed to be established in fenced holding pens for research or commercial reasons in Alaska and other areas. Native ranges of reindeer in Alaska were not on road systems, and the diet of the native reindeer had to be changed when they were translocated to small pens. Economics of transportation and feeding played an important role in the feasibility of translocation. Gathering and holding of reindeer for shipment, transport methods, adjustment of free-ranging reindeer to confinement, and a new diet were primary considerations to insure survival. Minimal psychologic stress of short duration, thermoregulation, and physical comfort were extremely important in carrying out a successful translocation. Receiving facilities, feed, and personnel were equally important. A minimum of one month was required to adjust reindeer to confinement and diet change.

  9. Lorentz-violating spinor electrodynamics and Penning traps

    Science.gov (United States)

    Ding, Yunhua; Kostelecký, V. Alan

    2016-09-01

    The prospects are explored for testing Lorentz- and C P T -violating quantum electrodynamics in experiments with Penning traps. We present the Lagrange density of Lorentz-violating spinor electrodynamics with operators of mass dimensions up to 6, and we discuss some of its properties. The theory is used to derive Lorentz- and C P T -violating perturbative shifts of the energy levels of a particle confined to a Penning trap. Observable signals are discussed for trapped electrons, positrons, protons, and antiprotons. Existing experimental measurements on anomaly frequencies are used to extract new or improved bounds on numerous coefficients for Lorentz and C P T violation, using sidereal variations of observables and comparisons between particles and antiparticles.

  10. The high-precision Penning trap mass spectrometer PENTATRAP

    Energy Technology Data Exchange (ETDEWEB)

    Doerr, Andreas; Bekker, Hendrik; Blaum, Klaus; Goncharov, Mikhail; Hoekel-Schmoeger, Christian [Max-Planck-Institut fuer Kernphysik, Heidelberg (Germany); Fakultaet fuer Physik und Astronomie, Ruprecht-Karls-Universitaet, Heidelberg (Germany); Boehm, Christine [Max-Planck-Institut fuer Kernphysik, Heidelberg (Germany); Fakultaet fuer Physik und Astronomie, Ruprecht-Karls-Universitaet, Heidelberg (Germany); Extreme Matter Institute EMMI, Helmholtz Gemeinschaft, Darmstadt (Germany); Crespo Lopez-Urrutia, Jose; Eliseev, Sergey; Repp, Julia; Roux, Christian; Sturm, Sven [Max-Planck-Institut fuer Kernphysik, Heidelberg (Germany); Novikov, Yuri [Petersburg Nuclear Physics Institute, Gatchina (Russian Federation); Ulmer, Stefan [Max-Planck-Institut fuer Kernphysik, Heidelberg (Germany); RIKEN Advanced Science Institute, Hirosawa, Wako, Saitama (Japan)

    2013-07-01

    Currently, the high-precision Penning trap mass spectrometer PENTATRAP is being built up at the Max-Planck-Institut fuer Kernphysik, Heidelberg, Germany. It aims at mass-ratio measurements of medium- to high-Z elements with uncertainties of a few parts in 10{sup 12}. Mass-ratios will be determined by the measurement of cyclotron frequency-ratios in the strong magnetic field of the trap. The experiment will host five identical cylindrical Penning traps and will allow for simultaneous cyclotron frequency determinations in all measurement traps. It will feature access to highly charged ions provided by EBITs. Measurements at PENTATRAP will contribute to various fields of physics. For example, input parameters for neutrino mass determinations will be provided with measurements of Q-values of relevant β-transitions. The current status of the experiment will be outlined in the talk.

  11. Non-linear PIC simulation in a penning trap

    Energy Technology Data Exchange (ETDEWEB)

    Delzanno, G. L. (Gian L.); Lapenta, G. M. (Giovanni M.); Finn, J. M. (John M.)

    2001-01-01

    We study the non-linear dynamics of a Penning trap plasma, including the effect of the finite length and end curvature of the plasma column. A new cylindrical PIC code, called KANDINSKY, has been implemented by using a new interpolation scheme. The principal idea is to calculate the volume of each cell from a particle volume, in the same manner as it is done for the cell charge. With this new method, the density is conserved along streamlines and artificial sources of compressibility are avoided. The code has been validated with a reference Eulerian fluid code. We compare the dynamics of three different models: a model with compression effects, the standard Euler model and a geophysical fluid dynamics model. The results of our investigation prove that Penning traps can really be used to simulate geophysical fluids.

  12. Recent developments in Penning-trap mass spectrometry

    Science.gov (United States)

    Block, M.

    2016-06-01

    Penning-trap mass spectrometry provides atomic masses with the highest precision. At accelerator-based on-line facilities it is applied to investigate exotic radionuclides in the context of tests of fundamental symmetries, nuclear structure studies, and nuclear astrophysics research. Recent progress in slowing down radioactive ion-beams in buffer-gas cells in combination with advanced ion-manipulation techniques has paved the way to reach nuclides ever-more far from stability. In this endeavor many efforts are underway to increase the sensitivity, the efficiency, and the precision of Penning-trap mass spectrometry. In this article some recent experimental developments are addressed with the focus on the phase-imaging ion-cyclotron-resonance technique and the Fourier transform ion-cyclotron-resonance technique.

  13. Tako-tsubo-like cardiomyopathy after EpiPen administration.

    Science.gov (United States)

    Zubrinich, C M; Farouque, H M Omar; Rochford, S E; Sutherland, M F

    2008-11-01

    Tako-tsubo-like cardiomyopathy is characterized by acute chest pain, electrocardiographic changes and increased cardiac enzymes in the absence of obstructive coronary vessel disease. We describe the development of tako-tsubo-like cardiomyopathy in an elderly woman after the use of an EpiPen for generalized urticaria and angioedema. As adrenaline may participate in the pathogenesis of this condition, the need for careful patient selection and education in the use of adrenaline self-injectors remains imperative.

  14. The EpiPen and the ischaemic finger.

    Science.gov (United States)

    Singh, Talvinder; Randhawa, Susheelwant; Khanna, Rakesh

    2007-08-01

    We present a case of a 24-year-old with a history of accidental injection of adrenaline from an EpiPen into the proximal aspect of her left index finger. Various methods were advocated to treat digital ischaemia but were of no benefit. Topical infiltration of phentolamine in 1 ml of lignocaine 2% was given at the puncture site with immediate results of resolution of digital ischaemia.

  15. Thermoplastic polymers surfaces for Dip-Pen Nanolithography of oligonucleotides

    Energy Technology Data Exchange (ETDEWEB)

    Suriano, Raffaella [Dipartimento di Chimica, Materiali e Ingegneria Chimica “Giulio Natta”, Politecnico di Milano, Piazza Leonardo da Vinci 32, 20133 Milano (Italy); Biella, Serena, E-mail: serena.biella@polimi.it [Dipartimento di Chimica, Materiali e Ingegneria Chimica “Giulio Natta”, Politecnico di Milano, Piazza Leonardo da Vinci 32, 20133 Milano (Italy); Cesura, Federico; Levi, Marinella; Turri, Stefano [Dipartimento di Chimica, Materiali e Ingegneria Chimica “Giulio Natta”, Politecnico di Milano, Piazza Leonardo da Vinci 32, 20133 Milano (Italy)

    2013-05-15

    Different thermoplastic polymers were spin-coated to prepare smooth surfaces for the direct deposition of end-group modified oligonucleotides by Dip-Pen Nanolithography. A study of the diffusion process was done in order to investigate the dependence of calibration coefficient and quality of deposited features on environmental parameters (temperature, relative humidity) and ink's molecular weight and functionality. The optimization of the process parameters led to the realization of high quality and density nanoarrays on plastics.

  16. Pen Branch Delta and Savannah River Swamp Hydraulic Model

    International Nuclear Information System (INIS)

    The proposed Savannah River Site (SRS) Wetlands Restoration Project area is located in Barnwell County, South Carolina on the southwestern boundary of the SRS Reservation. The swamp covers about 40.5 km2 and is bounded to the west and south by the Savannah River and to the north and east by low bluffs at the edge of the Savannah River floodplain. Water levels within the swamp are determined by stage along the Savannah River, local drainage, groundwater seepage, and inflows from four tributaries, Beaver Dam Creek, Fourmile Branch, Pen Branch, and Steel Creek. Historic discharges of heated process water into these tributaries scoured the streambed, created deltas in the adjacent wetland, and killed native vegetation in the vicinity of the delta deposits. Future releases from these tributaries will be substantially smaller and closer to ambient temperatures. One component of the proposed restoration project will be to reestablish indigenous wetland vegetation on the Pen Branch delta that covers about 1.0 km2. Long-term predictions of water levels within the swamp are required to determine the characteristics of suitable plants. The objective of the study was to predict water levels at various locations within the proposed SRS Wetlands Restoration Project area for a range of Savannah River flows and regulated releases from Pen Branch. TABS-MD, a United States Army Corps of Engineer developed two-dimensional finite element open channel hydraulic computer code, was used to model the SRS swamp area for various flow conditions

  17. Pen Branch Delta and Savannah River Swamp Hydraulic Model

    Energy Technology Data Exchange (ETDEWEB)

    Chen, K.F.

    1999-05-13

    The proposed Savannah River Site (SRS) Wetlands Restoration Project area is located in Barnwell County, South Carolina on the southwestern boundary of the SRS Reservation. The swamp covers about 40.5 km2 and is bounded to the west and south by the Savannah River and to the north and east by low bluffs at the edge of the Savannah River floodplain. Water levels within the swamp are determined by stage along the Savannah River, local drainage, groundwater seepage, and inflows from four tributaries, Beaver Dam Creek, Fourmile Branch, Pen Branch, and Steel Creek. Historic discharges of heated process water into these tributaries scoured the streambed, created deltas in the adjacent wetland, and killed native vegetation in the vicinity of the delta deposits. Future releases from these tributaries will be substantially smaller and closer to ambient temperatures. One component of the proposed restoration project will be to reestablish indigenous wetland vegetation on the Pen Branch delta that covers about 1.0 km2. Long-term predictions of water levels within the swamp are required to determine the characteristics of suitable plants. The objective of the study was to predict water levels at various locations within the proposed SRS Wetlands Restoration Project area for a range of Savannah River flows and regulated releases from Pen Branch. TABS-MD, a United States Army Corps of Engineer developed two-dimensional finite element open channel hydraulic computer code, was used to model the SRS swamp area for various flow conditions.

  18. Effect of calcium hydroxide application to cattle feedlot pens on Escherichia coli O157:H7 and total E. coli in pen surface manure

    Science.gov (United States)

    Introduction: Cattle and beef products are sources of the pathogen Escherichia coli O157:H7. Lime products have a long history of use in cattle production as disinfectants for sick pens, calving pens, and muddy areas, to control the spread of diseases. Lime may also be useful as a preharvest trea...

  19. Public debate on the Penly 3 project. Construction of an electronuclear production unit of the Penly site (Seine-Maritime)

    International Nuclear Information System (INIS)

    After a presentation of the objectives of the Penly 3 project, this report gives an overview of the context of electricity production (increasing world demand, geographically unbalanced energy reserves with fluctuating prices and a tendency to increase, French energy assessment, electricity peculiarities, electricity production and consumption in France in 2009, climate change issue). It presents the Penly 3 project and its alternatives within the frame of the French environment and energy policy. The project is then presented in terms of safety objectives, of design choices, of environmental improvements (water sampling, thermal, chemical and radioactive releases, wastes, sound and visual impact, foreseen cost and financing), and then in terms of socio-economical impact. The main steps of the project are briefly indicated

  20. Demonstration of the Double Penning Trap Technique with a Single Proton

    CERN Document Server

    Mooser, A; Franke, K.; Kracke, H.; Leiteritz, C.; Rodegheri, C.C.; Nagahama, H.; Schneider, G.; Smorra, C.; Blaum, K.; Matsuda, Y.; Quint, W.; Walz, J.; Yamazaki, Y.; Ulmer, S.; Yamazaki, Y; Ulmer, S

    2013-01-01

    Spin flips of a single proton were driven in a Penning trap with a homogeneous magnetic field. For the spin-state analysis the proton was transported into a second Penning trap with a superimposed magnetic bottle, and the continuous Stern-Gerlach effect was applied. This first demonstration of the double Penning trap technique with a single proton suggests that the antiproton magnetic moment measurement can potentially be improved by three orders of magnitude or more.

  1. Functional Evaluation of the Reusable JuniorSTAR® Half-Unit Insulin Pen

    OpenAIRE

    Klonoff, David; Nayberg, Irina; Rabbone, Ivana; Domenger, Catherine; Stauder, Udo; Oualali, Hamid; Danne, Thomas

    2015-01-01

    Background: The functional performance of the JuniorSTAR® (Sanofi, Paris, France) half-unit insulin pen was evaluated through a series of specific objective tests to assess the dose accuracy, pen weight, injection force, and dialing torque. Method: Pens (n = 60) were tested under standard atmospheric conditions with 3 different types of insulins manufactured by Sanofi (insulin glargine, insulin glulisine, and biphasic insulin isophane). The dose accuracy was tested according to the ISO 11608-...

  2. An all-at-once factorial method to optimize dip-pen deposition of liquid protein inks

    Science.gov (United States)

    Henning, A. K.; Rozhok, S.; Fragala, J.; Shile, R.; Ouyang, K.

    2013-03-01

    An all-at-once factorial method is presented, which optimizes protein ink deposition using microfabricated pens by identifying the pen design which writes the greatest number of uniform-size spots or droplets without re-inking. Pen features associated with capillary ink transport are varied according to statistical design-of-experiment (SDOE) principles, and evaluated using a special 1D pen array of twelve pens. Variable parameter pens are bracketed by control pens. Each pen array element embodies one component of the SDOE matrix. All parameters are evaluated simultaneously with a single droplet writing pass. Results can also be evaluated simultaneously, leading to rapid choice of those pen parameters which deliver the greatest number of printed features having the smallest coefficient of variation.

  3. An evaluation of exercise pen use by circus tigers (Pathera tigris tigris).

    Science.gov (United States)

    Nevill, Christian H; Friend, Ted H; Windom, Amy G

    2010-01-01

    This study quantified the behavior of 11 tigers during periodic access to an exercise pen throughout the day and night. The study determined the amount of time spent in the pen and the percentage of time spent performing stereotypic pacing, normal locomotor behavior, and lying down while in the pen. Average access to the exercise pen was 10 hr 49 min overnight and 5 hr 30 min during the day. At night, the tigers spent 29.1% of their time in the exercise pen, during which they paced 19.6% and performed normal locomotor behavior for 23.1% of that time. By day, they spent 40.4% of their time in the exercise pen, during which they paced 10.0% and performed normal locomotor behavior 35.7% of that time. The tigers spent the rest of the time in the pen lying down. Overall, tigers will utilize an exercise pen, spending a greater percentage of time in the pen during the day than at night and also performing less stereotyped pacing than at night.

  4. Observation of Spherical Focus in an Electron Penning Trap

    International Nuclear Information System (INIS)

    We produce simultaneously dense and well-confined nonneutral plasmas by spherical focusing. A small (3mm radius) Penning trap has low-energy electrons injected at a single pole of the sphere. Precisely when the trap parameters are adjusted to produce a spherical well, the system self-organizes into a spherical state through a bootstrapping mechanism which produces a hysteresis. Additional confirmation of the dense spherical focus is provided by electrons scattered by the central core. Core densities up to 35 times the Brillouin density have been inferred from the data. copyright 1996 The American Physical Society

  5. First direct Penning trap mass measurements on nobelium and lawrencium

    International Nuclear Information System (INIS)

    The mass measurements of the three nobelium isotopes 252-254No and the lawrencium isotope 255Lr measured with the Penning trap mass spectrometer SHIPTRAP/GSI have been evaluated. These were the first direct mass measurements of transfermium elements ever performed. The results mark the first step in the exploration of masses of even heavier nuclides which is planned at SHIPTRAP. The main objective is to measure the endpoints of α-decay chains starting from superheavy nuclei in the region of the predicted island of stability. The SHIPTRAP results were compared with previous measurements based on α-decay chains and new literature values were obtained.

  6. DESIGN AND ANALYSIS OF 3D PRINTING PEN

    OpenAIRE

    Mr. Nayan Jyoti Gogoi *, Prof. T. Jeyapoovan

    2016-01-01

    In present time 3d models and prototypes helping lot of engineers and in many technical areas mainly in design field to design a real model as quickly as possible with the help of 3d printing technology. The demand for 3d printing applications are increasing day by day and it is reaching to a height of end no of applications. In this project I am going to discuss how we can make an affordable and user friendly 3d printing device which can be used as a 3d printing pen as well as a device which...

  7. Recent results from the Penning trap mass spectrometer ISOLTRAP

    CERN Document Server

    Blaum, Klaus; Beck, D; Bollen, Georg; Delahaye, P; Guenaut, C; Herfurth, F; Kellerbauer, Alban G; Kluge, H J; Lunney, M D; Rodríguez, D; Schwarz, S; Schweikhard, L; Weber, C; Yazidjian, C

    2004-01-01

    In the last few years a number of new scientific highlights have been obtained by ISOLTRAP, the tandem Penning trap mass spectrometer for on-line mass measurements of short-lived radionuclides. The precise determination of nuclear binding energies far from stability includes nuclei that are produced at rates of 100 ions/s and with half-lives below 100 ms. The mass resolving power reaches 10$^{7}$ and the uncertainty of the resulting mass values has been pushed down to $1 \\times 10^{-8}$. In this article recent ISOLTRAP mass measurements are summarized and the current status of ISOLTRAP is presented.

  8. Mechanism of force mode dip-pen nanolithography

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Haijun, E-mail: yanghaijun@sinap.ac.cn, E-mail: swguo@sjtu.edu.cn, E-mail: wanghuabin@cigit.ac.cn [Key Laboratory for Thin Film and Microfabrication of the Ministry of Education, Research Institute of Micro/Nano Science and Technology, Shanghai Jiao Tong University, Shanghai 200240 (China); Interfacial Water Division and Key Laboratory of Interfacial Physics and Technology, Shanghai Institute of Applied Physics, CAS, Shanghai 201800 (China); Xie, Hui; Rong, Weibin; Sun, Lining [State Key Laboratory of Robotics and Systems, Harbin Institute of Technology, Harbin 150080 (China); Wu, Haixia; Guo, Shouwu, E-mail: yanghaijun@sinap.ac.cn, E-mail: swguo@sjtu.edu.cn, E-mail: wanghuabin@cigit.ac.cn [Key Laboratory for Thin Film and Microfabrication of the Ministry of Education, Research Institute of Micro/Nano Science and Technology, Shanghai Jiao Tong University, Shanghai 200240 (China); Wang, Huabin, E-mail: yanghaijun@sinap.ac.cn, E-mail: swguo@sjtu.edu.cn, E-mail: wanghuabin@cigit.ac.cn [Centre for Tetrahertz Research, Chongqing Institute of Green and Intelligent Technology, Chinese Academy of Sciences, Chongqing 400714 (China)

    2014-05-07

    In this work, the underlying mechanism of the force mode dip-pen nanolithography (FMDPN) is investigated in depth by analyzing force curves, tapping mode deflection signals, and “Z-scan” voltage variations during the FMDPN. The operation parameters including the relative “trigger threshold” and “surface delay” parameters are vital to control the loading force and dwell time for ink deposition during FMDPN. A model is also developed to simulate the interactions between the atomic force microscope tip and soft substrate during FMDPN, and verified by its good performance in fitting our experimental data.

  9. Assessing usability, label comprehension, pen robustness and pharmacokinetics of a self-administered prefilled autoinjector pen of methotrexate in patients with rheumatoid arthritis

    OpenAIRE

    Pachon, Jaime A; Kivitz, Alan J; Heuer, Kay-Uwe; Pichlmeier, Uwe

    2014-01-01

    Objective: To assess usability, bioavailability, and safety of subcutaneous self-administration of 0.3 mL of methotrexate 50 mg/mL solution via a prefilled autoinjector pen (methotrexate pen) in patients with rheumatoid arthritis. Methods: The study enrolled methotrexate-naïve and methotrexate-experienced patients aged ≥16 years. Visit 1 (Day 1) included methotrexate pen usage training with documentation, patient self-injection, and a patient-training questionnaire completed by the healthcare...

  10. A Penning-assisted subkilovolt coaxial plasma source

    International Nuclear Information System (INIS)

    A Penning-assisted 20 MW coaxial plasma source (plasma gun), which can achieve breakdown at sub-kV voltages, is described. The minimum breakdown voltage is about 400 V, significantly lower than previously reported values of 1-5 kV. The Penning region for electrons is created using a permanent magnet assembly, which is mounted to the inside of the cathode of the coaxial plasma source. A theoretical model for the breakdown is given. A 900 V 0.5 F capacitor bank supplies energy for gas breakdown and plasma sustainment from 4 to 6 ms duration. Typical peak gun current is about 100 kA and gun voltage between anode and cathode after breakdown is about 200 V. A circuit model is used to understand the current-voltage characteristics of the coaxial gun plasma. Energy deposited into the plasma accounts for about 60% of the total capacitor bank energy. This plasma source is uniquely suitable for studying multi-MW multi-ms plasmas with sub-MJ capacitor bank energy

  11. Spontaneous release of bacteriophage particles by Lactobacillus rhamnosus pen.

    Science.gov (United States)

    Jarocki, Piotr; Podleśny, Marcin; Pawelec, Jarosław; Malinowska, Agata; Kowalczyk, Sylwia; Targoński, Zdzisław

    2013-03-01

    The identification of bacteriophage proteins on the surface of Lactobacillus rhamnosus Pen was performed by LC-MS/MS analysis. Among the identified proteins, we found a phage-derived major tail protein, two major head proteins, a portal protein, and a host specificity protein. Electron microscopy of a cell surface extract revealed the presence of phage particles in the analyzed samples. The partial sequence of genes encoding the major tail protein for all tested L. rhamnosus strains was determined with specific primers designed in this study. Next, RT-PCR analysis allowed detection of the expression of the major tail protein gene in L. rhamnosus strain Pen at all stages of bacterial growth. The transcription of genes encoding the major tail protein was also proved for other L. rhamnosus strains used in this study. The present work demonstrates the spontanous release of prophage-encoded particles by a commercial probiotic L. rhamnosus strain, which did not significantly affect the bacterial growth of the analyzed strain.

  12. Instabilities of an electron cloud in a penning trap

    International Nuclear Information System (INIS)

    Penning traps have been used in recent years for a variety of experiments: measurement of electronic or nuclear g factors, high precision mass measurements, or plasma studies. Three dimensional confinement of charged particles is obtained by a static electric field applied between electrodes and superposition of a magnetic field. Storage times of many hours or even days can be obtained under well defined conditions and the stored particles are then subject to investigations. We have measured the storage instabilities of electrons in a Penning trap at low magnetic fields. These measurements are carried out. as a function of the trapping voltage, for different magnetic fields. It is seen that these instabilities occur at the same positions when the trapping voltage is expressed as a percentage of the maximum voltage, given by the stability limit. The characteristic frequencies at which these instabilities occur, obey a relation that is given by ηzωz + η+ω+ + η-ω- = 0, where ωz,ω+ and ω- are the axial, perturbed cyclotron and the magnetron frequencies of the trapped electrons respectively, and the n's are integers. The reason for these instabilities are attributed to higher order static perturbations in the trapping potential. (authors)

  13. Development of hollow anode penning ion source for laboratory application

    Science.gov (United States)

    Das, B. K.; Shyam, A.; Das, R.; Rao, A. D. P.

    2012-03-01

    The research work presented here focuses for the development of miniature penning type ion source. One hollow anode penning type ion source was developed in our laboratory. The size of the ion source is 38 mm diameter and 55 mm length. The ion source consists of two cathodes, a hollow anode and one piece of rare earth permanent magnet. The plasma was created in the plasma region between cathodes and the hollow anode. The J × B force in the region helps for efficient ionization of the gas even in the high vacuum region˜1×10 -5 Torr. The ions were extracted in the axial direction with help of the potential difference between the electrodes and the geometry of the extraction angle. The effect of the extraction electrode geometry for efficient extraction of the ions from the plasma region was examined. This ion source is a self extracted ion source. The self extracted phenomena reduce the cost and the size of the ion source. The extracted ion current was measured by a graphite probe. An ion current of more than 200 μA was observed at the probe placed 70 mm apart from the extraction electrode. In this paper, the structure of the ion source, effect of operating pressure, potential difference and the magnetic field on the extracted ion current is reported.

  14. Development of hollow anode penning ion source for laboratory application

    International Nuclear Information System (INIS)

    The research work presented here focuses for the development of miniature penning type ion source. One hollow anode penning type ion source was developed in our laboratory. The size of the ion source is 38 mm diameter and 55 mm length. The ion source consists of two cathodes, a hollow anode and one piece of rare earth permanent magnet. The plasma was created in the plasma region between cathodes and the hollow anode. The J × B force in the region helps for efficient ionization of the gas even in the high vacuum region∼1×10-5 Torr. The ions were extracted in the axial direction with help of the potential difference between the electrodes and the geometry of the extraction angle. The effect of the extraction electrode geometry for efficient extraction of the ions from the plasma region was examined. This ion source is a self extracted ion source. The self extracted phenomena reduce the cost and the size of the ion source. The extracted ion current was measured by a graphite probe. An ion current of more than 200 μA was observed at the probe placed 70 mm apart from the extraction electrode. In this paper, the structure of the ion source, effect of operating pressure, potential difference and the magnetic field on the extracted ion current is reported.

  15. Vegetation survey of Pen Branch and Four Mile Creek wetlands

    Energy Technology Data Exchange (ETDEWEB)

    1992-01-01

    One hundred-fifty plots were recently sampled (vegetational sampling study) at the Savannah River Site (SRS). An extensive characterization of the vascular flora, in four predetermined strata (overstory, Understory, shrub layer, and ground cover), was undertaken to determine dominance, co-dominance, and the importance value (I.V.) of each species. These results will be used by the Savannah River Laboratory (SRL) to evaluate the environmental status of Four Mile Creek, Pen Branch, and two upland pine stands. Objectives of this study were to: Describe in detail the plant communities previously mapped with reference to the topography and drainage, including species of plants present: Examine the successional trends within each sampling area and describe the extent to which current vegetation communities have resulted from specific earlier vegetation disturbances (e.g., logging and grazing); describe in detail the botanical field techniques used to sample the flora; describe the habitat and location of protected and/or rare species of plants; and collect and prepare plant species as herbarium quality specimens. Sampling was conducted at Four Mile Creek and Pen Branch, and in two upland pine plantations of different age growth.

  16. Vegetation survey of Pen Branch and Four Mile Creek wetlands

    Energy Technology Data Exchange (ETDEWEB)

    1992-10-01

    One hundred-fifty plots were recently sampled (vegetational sampling study) at the Savannah River Site (SRS). An extensive characterization of the vascular flora, in four predetermined strata (overstory, Understory, shrub layer, and ground cover), was undertaken to determine dominance, co-dominance, and the importance value (I.V.) of each species. These results will be used by the Savannah River Laboratory (SRL) to evaluate the environmental status of Four Mile Creek, Pen Branch, and two upland pine stands. Objectives of this study were to: Describe in detail the plant communities previously mapped with reference to the topography and drainage, including species of plants present: Examine the successional trends within each sampling area and describe the extent to which current vegetation communities have resulted from specific earlier vegetation disturbances (e.g., logging and grazing); describe in detail the botanical field techniques used to sample the flora; describe the habitat and location of protected and/or rare species of plants; and collect and prepare plant species as herbarium quality specimens. Sampling was conducted at Four Mile Creek and Pen Branch, and in two upland pine plantations of different age growth.

  17. 多波段相关光子光谱分布与时间相关性测量实验研究%Research on the Distribution of Broad-Band Correlated Photon Spectra and the Measurement of Time-Correlation

    Institute of Scientific and Technical Information of China (English)

    高冬阳; 李健军; 夏茂鹏; 郑小兵

    2016-01-01

    基于相关光子的定标技术能够实现“无标准传递”绝对定标,研究相关光子的光谱辐射特性及时间相关特性对遥感器在宽波段的辐射定标具有重要意义。为满足光电探测器在宽谱段量子效率定标需求,基于相关光子的定标技术有必要从单一波段向更多波段扩展。根据自发参量下转换所满足的相位匹配条件,推导出相关光子在晶体内的非共线角计算公式,通过数值模拟相关光子光谱辐射角度分布规律,优化晶体相位匹配角,使得自发参量下转换产生的相关光子具有宽光谱分布,并且相关光子辐射角度与光谱波长能够一一对应。根据光谱分布数值模拟结果,建立了多波段相关光子的光谱分布和时间相关性测量实验系统,利用该系统测量了四对相关光子的光谱分布、符合计数、相关时间以及偏振特性。其中,测量的光谱分布范围为633~808 nm,最大光谱分布测量偏差为1.51 mm,光谱分布实验测量结果与数值模拟结果符合一致;测量了四对相关光子对的相关时间,最小相关时间为0.32 ns,并在实验中观察到了“符合三峰”现象;相关光子单光子计数及符合计数与泵浦光的偏振方向呈正弦函数关系。实验研究表明,相关光子对具有可见光~近红外宽波段分布、时间相关及偏振特性。论文研究结果在国内外尚属首次报道,该研究结果有望应用于光电探测器在多波段的辐射定标。%The correlated photon technique makes it possible to achieve a radiation calibration processing without chain transfer-ring.The study of the spectral radiation character and time correlation of the photon is of great significance for broad-band radio-metric calibration.To absolutely calibrate quantum efficiency of photoelectric detector,it is necessary to extend calibration band from single band to more bands.According to the phase-matching condition of the spontaneous

  18. Assessing usability, label comprehension, pen robustness and pharmacokinetics of a self-administered prefilled autoinjector pen of methotrexate in patients with rheumatoid arthritis

    Directory of Open Access Journals (Sweden)

    Jaime A Pachon

    2014-12-01

    Full Text Available Objective: To assess usability, bioavailability, and safety of subcutaneous self-administration of 0.3 mL of methotrexate 50 mg/mL solution via a prefilled autoinjector pen (methotrexate pen in patients with rheumatoid arthritis. Methods: The study enrolled methotrexate-naïve and methotrexate-experienced patients aged ≥16 years. Visit 1 (Day 1 included methotrexate pen usage training with documentation, patient self-injection, and a patient-training questionnaire completed by the healthcare professional. Visit 2 (Days 8–10 included evaluation of patient self-injection through four scenarios: holding needle in place for 5 s, confirming methotrexate delivery, skin pinch, and pen disposal. At Visit 2, patient opinion and training retention (since Visit 1 were also assessed. Pharmacokinetic parameters were assessed in 25 patients, who were stratified by body weight and randomized to receive injections in the abdomen or the upper thigh. Results: At Visit 1, 12 of 106 patients had questions about the pen, and 4 required self-injection assistance. At Visit 2, the mean performance rating for all scenarios was ≥9.8 (scale: 1 (very difficult−10 (very easy. Successful completion rates were 96.2%–100%; 91.3%–100% of patients required no assistance. Impressions of the pen were favorable; 98.1% of patients passed the written examination. All methotrexate pens effectively delivered 0.3 mL methotrexate and were intact after use. Body weight >100 kg significantly decreased total and peak methotrexate exposure when administered abdominally. No adverse effects resulted in drug discontinuation. Conclusion: The methotrexate pen was used with a high degree of effectiveness, satisfaction, and safety, indicating that this delivery system may be a viable option for patients requiring subcutaneous methotrexate.

  19. Update of Research Activities Related to the Pen Branch Restoration Effort on the Savannah River Site

    Energy Technology Data Exchange (ETDEWEB)

    Kolka, R.K.; Trettin, C.C.; Nelson, E.A.

    2000-01-01

    Comprehensive description of Pen Branch restoration plans and related research projects documented in the 1996 annual report. The purpose of the annual report is to update progress over the past year and to project 1998 research expectations for studies included in the Pen Branch Restoration Project. A full updated reference list is provided at the end of the report.

  20. Gender Representation in an Electronic City Hall: Female Adoption of Santa Monica's PEN System.

    Science.gov (United States)

    Collins-Jarvis, Lori A.

    1993-01-01

    Discussion of the use of electronic networking systems by women focuses on a study of their use of the Public Electronic Network (PEN) in Santa Monica (California). Characteristics of PEN that contributed to female adoption are described; gender, political participation, and motivation are examined; and future research is suggested. (46…

  1. Lessons from the operation of the `Penning-Fluorescent' TPC and prospects

    CERN Document Server

    Gonzalez-Diaz, Diego; Castel, J; Cebrian, S; Dafni, T; Garcia, J A; Gomez, H; Herrera, D C; Iguaz, F J; Irastorza, I G; Lagraba, A; Luzon, G; Rodriguez, A; Ruiz-Choliz, E; Ferrer-Ribas, A Tomas E; Giomataris, I

    2015-01-01

    We have recently reported the development of a new type of high-pressure Xenon time projection chamber operated with an ultra-low diffusion mixture and that simultaneously displays Penning effect and fluorescence in the near-visible region (300 nm). The concept, dubbed `Penning-Fluorescent' TPC, allows the simultaneous reconstruction of primary charge and scintillation with high topological and calorimetric fidelity.

  2. The Effect of a College Pen Incentive on Survey Response Rate among Recent College Graduates

    Science.gov (United States)

    Stange, Jonathan P.; Zyzanski, Stephen J.

    2011-01-01

    Incentives have shown a variable effect in improving survey response rates, but the effect of a pen from an organization to which the respondent has loyalty has not been studied. Recent college graduates were randomized to receive or not receive a college logo pen accompanying an initial survey mailing. Among 119 total respondents, there were no…

  3. H- beam emittance measurements for the penning and the asymmetric, grooved magnetron surface-plasma sources

    International Nuclear Information System (INIS)

    Beam-intensity and emittance measurements show that the H- beam from our Penning surface-plasma source (SPS) has twice the intensity and ten times the brightness of the H- beam from an asymmetric, grooved magnetron SPS. We deduce H- ion temperatures of 5 eV for the Penning SPS and 22 eV for the asymmetric, grooved magnetron

  4. 9 CFR 309.1 - Ante-mortem inspection in pens of official establishments.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Ante-mortem inspection in pens of... AND VOLUNTARY INSPECTION AND CERTIFICATION ANTE-MORTEM INSPECTION § 309.1 Ante-mortem inspection in...) Such ante-mortem inspection shall be made in pens on the premises of the establishment at which...

  5. "Aloha", Hoosier! A Pen-Pal Activity in the Third Grade

    Science.gov (United States)

    Callahan, Raymond; Chan, Kam Chi

    2007-01-01

    Ray, a preservice teacher in Indiana, and Maxine, a 35-year teaching veteran in Hawai'i, set up a pen-pal program for the third grade students in their respective classrooms, 4,000 miles apart. This pen-pal program, used in conjunction with children's literature and community and technology resources, brought about memorable learning experiences.…

  6. A Context-Aware Infrastructure for Supporting Applications with Pen-Based Interaction

    Institute of Scientific and Technical Information of China (English)

    LI Yang(栗阳); GUAN ZhiWei(关志伟); DAI GuoZhong(戴国忠); REN XiangShi(任向实); HAN Yong(韩勇)

    2003-01-01

    Pen-based user interfaces which leverage the affordances of the pen provide userswith more flexibility and natural interaction. However, it is difficult to construct usable pen-baseduser interfaces because of the lack of support for their development. Toolkit-level support has beenexploited to solve this problem, but this approach makes it hard to gain platform independence,easy maintenance and easy extension. In this paper a context-aware infrastructure is created,called WEAVER, to provide pen interaction services for both novel pen-based applications andlegacy GUI-based applications. WEAVER aims to support the pen as another standard interactivedevice along with the keyboard and mouse and present a high-level access interface to pen input.It employs application context to tailor its service to different applications. By modeling theapplication context and registering the relevant action adapters, WEAVER can offer services,such as gesture recognition, continuous handwriting and other fundamental ink manipulations, toappropriate applications. One of the distinct features of WEAVER is that off-the-shelf GUI-basedsoftware packages can be easily enhanced with pen interaction without modifying the existing code.In this paper, the architecture and components of WEAVER are described. In addition, examplesand feedbacks of its use are presented.

  7. Rap van tong, scherp van pen. Literaire discussiecultuur in Nederlandse praatjespamfletten (circa 1600-1750)

    NARCIS (Netherlands)

    Dingemanse, C.W.

    2008-01-01

    In the early modern period pamphlets constituted the most important medium to influence public opinion in the Netherlands. The thesis Rap van tong, scherp van pen (Glib tongues, sharp pens) focuses on the literary and rhetorical aspects of a remarkable type of pamphlet called praatje (small-talk), w

  8. Flexible AMOLED display on polyethylene napthalate (PEN) foil with metal-oxide TFT backplane

    NARCIS (Netherlands)

    Tripathi, A.K.; Putten, B. van der; Steen, J.L. van der; Tempelaars, K.; Cobb, B.; Ameys, M.; Ke, T.H.; Myny, K.; Steudel, S.; Nag, M.; Schols, S.; Vicca, P.; Smout, S.; Genoe, J.; Heremans, P.; Yakimets, I.; Gelinck, G.H.

    2012-01-01

    We present a top emitting monochrome AMOLED display with 85dpi resolution using an amorphous Indium-Gallium-Zinc-Oxide (IGZO) TFT backplane on PEN-foil. Maximum processing temperature was limited to 150 °C in order to ensure an overlay accuracy < 3μm on PEN foil. The backplane process flow is based

  9. Operation of the CSNS Penning surface H~- ion source

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    The accelerator complex of the China Spallation Neutron Source (CSNS) consists of a H- linear accelerator (linac) and a rapid cycling synchrotron (RCS). The linac contains a Penning surface H- ion source. The designed energy and the beam current of the source are 50 keV and 20 mA respectively, with a normalized root mean square (norm. rms.) emittance of 0.2π mm mrad. The manufactures and tests of the discharge chamber are in great progress. The construction of H- ion source test stand has been completed, and the operation of the source is also in progress. Stable H- ion beams with energy of 50 keV and current up to 50 mA are attained. Emittance measurement for the H- beam is being prepared.

  10. Analysis of electron dynamics in non-ideal Penning traps

    Energy Technology Data Exchange (ETDEWEB)

    Coppa, G.; Mulas, R. [Dipartimento Energia, Politecnico di Torino, 10129 Torino (Italy); D' Angola, A. [Dipartimento di Ingegneria e Fisica dell' Ambiente, Universita della Basilicata, 85100 Potenza (Italy)

    2012-06-15

    Penning traps that are used for particular applications, such as in ion pump technology, Larmor, bouncing, and diocotron frequencies, can be of the same order of magnitude. The paper deals with the dynamics of electrons confined in such devices starting from the study of the properties of the trajectories. In cases of interest, in which electron-neutral collision frequency is much smaller with respect to the characteristic frequencies of the motion, suitable time averages of the trajectories are introduced in order to simplify the analysis of the problem. In the work, time averages have been calculated in a simple way by using an approximate r-z decoupling of the effective potential. Results obtained with the method are presented and discussed in both linear and nonlinear regimes.

  11. Study of Ammonia Emissions in a Ventilated Pig Pen

    DEFF Research Database (Denmark)

    Rong, Li

    reported in literature, little effort has been made to investigate the accuracy of current Henry’s law constant for modeling ammonia mass transfer process and study ammonia emissions in a full scale pig pen from fluid dynamics by CFD simulations. This will be the main objectives of this study. The ammonia...... the accuracy of Henry’s law constants to determine the ammonia concentration in the air through the air-liquid interface. None of the present Henry’s law constant models provide a respectable agreement between simulated and measured results. A simplified model to determine the ammonia concentration in the air...... through the air-liquid interface is suggested from vapor-liquid equilibrium properties of ammonia water. Furthermore, the effects of airflow and temperature on ammonia mass transfer coefficient are also analyzed under different concentration boundary conditions determined by various Henry’s law constant...

  12. Rapid crystallization of externally produced ions in a Penning trap

    CERN Document Server

    Murboeck, T; Birkl, G; Noertershaeuser, W; Thompson, R C; Vogel, M

    2016-01-01

    We have studied the cooling dynamics, formation process and geometric structure of mesoscopic crystals of externally produced magnesium ions in a Penning trap. We present a cooling model and measurements for a combination of buffer gas cooling and laser cooling which has been found to reduce the ion kinetic energy by eight orders of magnitude from several hundreds of eV to micro-eV and below within seconds. With ion numbers of the order of 1000 to 100000, such cooling leads to the formation of ion Coulomb crystals which display a characteristic shell structure in agreement with theory of non-neutral plasmas. We show the production and characterization of two-species ion crystals as a means of sympathetic cooling of ions lacking a suitable laser-cooling transition.

  13. Dip-pen nanolithography-assisted protein crystallization.

    Science.gov (United States)

    Ielasi, Francesco S; Hirtz, Michael; Sekula-Neuner, Sylwia; Laue, Thomas; Fuchs, Harald; Willaert, Ronnie G

    2015-01-14

    We demonstrate the use of dip-pen nanolithography (DPN) to crystallize proteins on surface-localized functionalized lipid layer arrays. DOPC lipid layers, containing small amounts of biotin-DOPE lipid molecules, were printed on glass substrates and evaluated in vapor diffusion and batch crystallization screening setups, where streptavidin was used as a model protein for crystallization. Independently of the crystallization system used and the geometry of the lipid layers, nucleation of streptavidin crystals occurred specifically on the DPN-printed biotinylated structures. Protein crystallization on lipid array patches is also demonstrated in a microfluidic chip, which opens the way toward high-throughput screening to find suitable nucleation and crystal growth conditions. The results demonstrate the use of DPN in directing and inducing protein crystallization on specific surface locations.

  14. The Penning trap system used by the BASE experiment

    CERN Multimedia

    Marcastel, Fabienne

    2015-01-01

    A cut-away schematic of the Penning trap system used by BASE. The experiment receives antiprotons from CERN's AD; negative hydrogen ions are formed during injection into the apparatus. The set-up works with only a pair of particles at a time, while a cloud of a few hundred others are held in the reservoir trap, for future use. Here, an antiproton is in the measurement trap, while the negative hydyrogen ion is in held by the downstream park electrode. When the antiproton has been measured, it is moved to the upstream park electrode and the hydrogen ion is brought in to the measurement trap. This is repeated thousands of times, enabling a high-precision comparison of the charge-to-mass ratios of the two particles.

  15. Recent results from the Penning trap mass spectrometer JYFLTRAP

    International Nuclear Information System (INIS)

    Accurate mass determination employing Penning ion traps has gained increasing importance after the installation of several new on-line facilities at accelerator labs. These setups combine unique production possibilities for rare isotopes with elaborate ion-capture and manipulation techniques. Since the final commissioning of the JYFLTRAP setup at the IGISOL facility in Jyvaeskylae, the masses of more than 200 short-lived nuclides have been measured. Their knowledge applies to studies on nuclear structure, the modeling of nucleosynthesis processes, tests of the conserved vector current (CVC) hypothesis and the unitarity of the CKM matrix, and furthermore, can help to assist in ongoing searches of neutrinoless double-beta decays. This presentation focuses on recent highlights studied at JYFLTRAP

  16. Recent results from the Penning trap mass spectrometer JYFLTRAP

    Energy Technology Data Exchange (ETDEWEB)

    Weber, Christine; Elomaa, Viki-Veikko; Eronen, Tommi; Hakala, Jani; Jokinen, Ari; Kankainen, Anu; Rahaman, Saidur; Rissanen, Juho; Aeystoe, Juha [Department of Physics, (YFL), University of Jyvaeskylae (Finland)

    2009-07-01

    Accurate mass determination employing Penning ion traps has gained increasing importance after the installation of several new on-line facilities at accelerator labs. These setups combine unique production possibilities for rare isotopes with elaborate ion-capture and manipulation techniques. Since the final commissioning of the JYFLTRAP setup at the IGISOL facility in Jyvaeskylae, the masses of more than 200 short-lived nuclides have been measured. Their knowledge applies to studies on nuclear structure, the modeling of nucleosynthesis processes, tests of the conserved vector current (CVC) hypothesis and the unitarity of the CKM matrix, and furthermore, can help to assist in ongoing searches of neutrinoless double-beta decays. This presentation focuses on recent highlights studied at JYFLTRAP.

  17. RESEARCHES REGARDING THE MAIN REPRODUCTION INDICATORS DETERMINATED IN SOWS, STAND GESTATION PEN TIPE

    Directory of Open Access Journals (Sweden)

    RAMONA UNTARU

    2013-12-01

    Full Text Available Current researches were carried out with the goal to quantisize the lost from the weaning to early gestation at the sows housed in open pen gestation. In this trail we tested two pen types, different not only by size, but also by feeders’ emplacement. The main reproduction indicators that we calculated until the 28 gestation day were the proportion of sows in heat after weaning, the weaning to estrus interval and the gestation rates. The weaning to estrus interval was about 4 to 7 days, most sows were in heat in the day 5 and 6 days after weaning. The percent of heat detection after weaning was 71.42% for the small pens and 70.71% for the big pens (differences statistically non significant, chi test value was 0.983. The gestation rate at 28 days after insemination was 91.62% for the small pens and 94.72% for the large pens (chi test value 0,959, statistically non significant differences. The overpopulation for heat induction and after that chipping animals together in those pens, show that the lost are up to 40.47%, between weaning – day 28 of gestation.

  18. Identification of colorants in pigmented pen inks by laser desorption mass spectrometry.

    Science.gov (United States)

    Papson, Kaitlin; Stachura, Sylwia; Boralsky, Luke; Allison, John

    2008-01-01

    Pigments are rapidly replacing dyes as colorants in pen and printer inks, due to their superior colors and stability. Unfortunately, tools commonly used in questioned document examination for analyzing pen inks, such as TLC, cannot be used for the analysis of insoluble pigments on paper. Laser desorption mass spectrometry is demonstrated here as a tool for analyzing pigment-based pen inks. A pulsed nitrogen laser can be focused onto a pen stroke from a pigmented ink pen on paper, and positive and negative ions representative of the pigment can be generated for subsequent mass spectrometric analysis. Targeted pens for this work were a set of Uni-ball 207 pigmented ink pens containing blue, light blue, orange, green, violet, red, pink, and black inks. Copper phthalocyanine was identified as the pigment used to make both blue inks. A mixture of halogenated copper phthalocyanines were identified in the green ink. Unexpectedly, the pink ink was found to contain a red pigment, Pigment Red 12, treated with a mixture of water-soluble dyes. Each sample yielded ions representative of the pigments present.

  19. Identification of colorants in pigmented pen inks by laser desorption mass spectrometry.

    Science.gov (United States)

    Papson, Kaitlin; Stachura, Sylwia; Boralsky, Luke; Allison, John

    2008-01-01

    Pigments are rapidly replacing dyes as colorants in pen and printer inks, due to their superior colors and stability. Unfortunately, tools commonly used in questioned document examination for analyzing pen inks, such as TLC, cannot be used for the analysis of insoluble pigments on paper. Laser desorption mass spectrometry is demonstrated here as a tool for analyzing pigment-based pen inks. A pulsed nitrogen laser can be focused onto a pen stroke from a pigmented ink pen on paper, and positive and negative ions representative of the pigment can be generated for subsequent mass spectrometric analysis. Targeted pens for this work were a set of Uni-ball 207 pigmented ink pens containing blue, light blue, orange, green, violet, red, pink, and black inks. Copper phthalocyanine was identified as the pigment used to make both blue inks. A mixture of halogenated copper phthalocyanines were identified in the green ink. Unexpectedly, the pink ink was found to contain a red pigment, Pigment Red 12, treated with a mixture of water-soluble dyes. Each sample yielded ions representative of the pigments present. PMID:18279246

  20. Dielectric study of the glass transition of PET/PEN blends

    OpenAIRE

    Sellares, J.; Diego, J A; Canadas, J. C.; Mudarra, M.; Belana, J.; Colomer, P.; Roman, F.; Y. Calventus

    2012-01-01

    An analysis of the glass transition of four materials with similar chemical structures is performed: PET, PEN and two PET/PEN blends (90/10 and 70/30 w/w). During the melt processing of the blends transesterification reactions yield block and random PET/PEN copolymers that act as compatibilizers. The blends obtained in this way have been characterized by 1H-NMR and DSC. A degree of randomness of 0.38 and 0.26 has been found for the 90/10 and 70/30 copolymers. It is shown by DSC that this copo...

  1. Psychometric Assessment of the Injection Pen Assessment Questionnaire (IPAQ: measuring ease of use and preference with injection pens for human growth hormone

    Directory of Open Access Journals (Sweden)

    Pleil Andreas M

    2012-10-01

    Full Text Available Abstract Purpose To examine the psychometric properties of the Injection Pen Assessment Questionnaire (IPAQ including the following: 1 item and scale characteristics (e.g., frequencies, item distributions, and factor structure, 2 reliability, and 3 validity. Methods Focus groups and one-on-one dyad interviews guided the development of the IPAQ. The IPAQ was subsequently tested in 136 parent–child dyads in a Phase 3, 2-month, open-label, multicenter trial for a new Genotropin® disposable pen. Factor analysis was performed to inform the development of a scoring algorithm, and reliability and validity of the IPAQ were evaluated using the data from this two months study. Psychometric analyses were conducted separately for each injection pen. Results Confirmatory factor analysis provides evidence supporting a second order factor solution for four subscales and a total IPAQ score. These factor analysis results support the conceptual framework developed from previous qualitative research in patient dyads using the reusable pen. However, the IPAQ subscales did not consistently meet acceptable internal consistency reliability for some group level comparisons. Cronbach’s alphas for the total IPAQ score for both pens were 0.85, exceeding acceptable levels of reliability for group comparisons. Conclusions The total IPAQ score is a useful measure for evaluating ease of use and preference for injection pens in clinical trials among patient dyads receiving hGH. The psychometric properties of the individual subscales, mainly the lower internal consistency reliability of some of the subscales and the predictive validity findings, do not support the use of subscale scores alone as a primary endpoint.

  2. penORNL: a parallel Monte Carlo photon and electron transport package using PENELOPE

    Energy Technology Data Exchange (ETDEWEB)

    Bekar, Kursat B. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Miller, Thomas Martin [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Patton, Bruce W. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Weber, Charles F. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2015-01-01

    The parallel Monte Carlo photon and electron transport code package penORNL was developed at Oak Ridge National Laboratory to enable advanced scanning electron microscope (SEM) simulations on high performance computing systems. This paper discusses the implementations, capabilities and parallel performance of the new code package. penORNL uses PENELOPE for its physics calculations and provides all available PENELOPE features to the users, as well as some new features including source definitions specifically developed for SEM simulations, a pulse-height tally capability for detailed simulations of gamma and x-ray detectors, and a modified interaction forcing mechanism to enable accurate energy deposition calculations. The parallel performance of penORNL was extensively tested with several model problems, and very good linear parallel scaling was observed with up to 512 processors. penORNL, along with its new features, will be available for SEM simulations upon completion of the new pulse-height tally implementation.

  3. Noble-gas ionization in the ion source with Penning effect

    International Nuclear Information System (INIS)

    By additional use of that the ion source efficiency can be increased the Penning ionization. The results of estimates of certain coefficients for the processes taking place in the plasma ion sources are presented

  4. Dynamic monitoring of weight data at the pen vs at the individual level

    DEFF Research Database (Denmark)

    Jensen, Dan; Toft, Nils; Kristensen, A. R. K.;

    The PigIT project, led by the University of Copenhagen, aims at improving welfare and productivity in growing pigs using ICT methods. Automatically and manually recorded data are currently being collected in a production herd. One of the first steps of the project is to make use of the manually...... recorded weight data from finisher pigs. Data are collected at insertion and at the exit of the first pigs in the pen, and in few pens, the weight is recorded weekly. Dynamic linear models are fitted on the weight data, at the pig level (univariate), at the double pen level using averaged weight...... (univariate) and using individual pig values as parameters in a hierarchical (multivariate) model including section, double pen, and individual level. Variance components of the different models are estimated using the Expectation Maximization algorithm. The difference of information obtained at the...

  5. Cooling of radioactive ions with the Penning trap REXTRAP

    CERN Document Server

    Ames, F; Delahaye, P; Forstner, O; Huber, G; Kester, O; Reisinger, K; Schmidt, P

    2005-01-01

    Cooling of radioactive ion beams in a Penning trap is an essential component of the post-accelerator REX-ISOLDE at CERN. Prior to their charge-breeding and acceleration, ions from the on-line mass separator ISOLDE are accumulated, cooled and bunched with REXTRAP. This beam preparation provides short ion pulses with low emittance, key ingredient for a high efficiency of REX-ISOLDE. Two different cooling techniques have been investigated with REXTRAP. Both rely on the use of a buffer gas as the coolant but differ in the way the transversal compression of the stored ion cloud is achieved. Sideband cooling with a light buffer gas as coolant is the standard technique used at REXTRAP so far. With this technique an efficiency of about 45% for the injection, cooling, and extraction process has been obtained for stable and radioactive ions. For about 105 simultaneously stored ions the resulting emittance of the extracted ion pulses is about 10pimm mrad at 30 keV beam energy. For much larger numbers of ions shifts of t...

  6. Squid Pen Chitin Chitooligomers as Food Colorants Absorbers

    Directory of Open Access Journals (Sweden)

    Tzu-Wen Liang

    2015-01-01

    Full Text Available One of the most promising applications of chitosanase is the conversion of chitinous biowaste into bioactive chitooligomers (COS. TKU033 chitosanase was induced from squid pen powder (SPP-containing Bacillus cereus TKU033 medium and purified by ammonium sulfate precipitation and column chromatography. The enzyme was relatively more thermostable in the presence of the substrate and had an activity of 93% at 50 °C in a pH 5 buffer solution for 60 min. Furthermore, the enzyme used for the COS preparation was also studied. The enzyme products revealed various mixtures of COS that with different degrees of polymerization (DP, ranging from three to nine. In the culture medium, the fermented SPP was recovered, and it displayed a better adsorption rate (up to 96% for the disperse dyes than the water-soluble food colorants, Allura Red AC (R40 and Tartrazne (Y4. Fourier transform-infrared spectroscopic (FT-IR analysis proved that the adsorption of the dyes onto fermented SPP was a physical adsorption. Results also showed that fermented SPP was a favorable adsorber and could be employed as low-cost alternative for dye removal in wastewater treatment.

  7. Beyond the Brillouin limit with the Penning fusion experiment

    International Nuclear Information System (INIS)

    Several years ago, it was proposed that a dense nonneutral plasma could be produced in a Penning trap. Nonneutral plasmas have excellent confinement. Thus, such a dense plasma might produce simultaneously high density and good confinement (as needed for fusion). Recently, this theoretical conjecture has been demonstrated in a small (3 mm radius) electron experiment (PFX). Densities up to 35 times the Brillouin density (limiting number density in a static trap) have been inferred from the observed strong (100:1) spherical focussing. Electrons are injected at low energy from a single pole of the sphere. A surprising observation is the self-organization of the system into a spherical state, which occurs precisely when the trap parameters are adjusted to produce a spherical well. This organization is observed by a bootstrapping which produces a hysteresis. Additional observations which confirm the dense spherical focus are energy-scattered electrons and deflections of an electron probe beam by the space charge of the central focus

  8. The global diversity of sea pens (Cnidaria: Octocorallia: Pennatulacea.

    Directory of Open Access Journals (Sweden)

    Gary C Williams

    Full Text Available Recent advances in deep-sea exploration technology coupled with an increase in worldwide biotic surveys, biological research, and underwater photography in shallow water marine regions such as coral reefs, has allowed for a relatively rapid expansion of our knowledge in the global diversity of many groups of marine organisms. This paper is part of the PLoS ONE review collection of WoRMS (the Worldwide Register of Marine Species, on the global diversity of marine species, and treats the pennatulacean octocorals, a group of cnidarians commonly referred to as sea pens or sea feathers. This also includes sea pansies, some sea whips, and various vermiform taxa. Pennatulaceans are a morphologically diverse group with an estimated 200 or more valid species, displaying worldwide geographic and bathymetric distributions from polar seas to the equatorial tropics and from intertidal flats to over 6100 m in depth. The paper treats new discoveries and taxa new to science, and provides greater resolution in geographic and bathymetric distributions data than was previously known, as well as descriptions of life appearances in life and in situ observations at diverse depth.

  9. Aracnologias - As tecituras de Penélope

    Directory of Open Access Journals (Sweden)

    Cristina Stevens

    2009-12-01

    Full Text Available Análise da personagem Penélope, de Homero, e a transformação ousada de Joyce dessa representação clássica da fidelidade feminina em Molly Bloom, a esposa infiel, sexualizada, trivial, lírica. Essas duas personagens são comparadas com sua mais recente recriação em The Penelopiad (2005, da escritora canadense Margaret Atwood. Uma importante categoria analítica dos estudos feministas e de gênero, a questão da voz é enfatizada na presente análise; essa personagem feminina é objeto da narrativa masculina (A Odisseia e Ulisses, mas no romance de Atwood essa personagem é sujeito de sua narrativa, elaborando uma tecitura “penelopeana” transgressora da versão clássica. Focalizaremos também o poder do silêncio na narrativa de autoria feminina, através do monólogo interior de Molly e da voz que fala do mundo dos mortos em The Penelopiad. Os conceitos de “abjeto” e “linguagem semiótica” de Kristeva são base para nosso trabalho, o qual problematiza a aparente imagem de passividade dessas mulheres que buscam o controle sobre suas vidas.

  10. Cooling of highly charged ions in a Penning trap

    Energy Technology Data Exchange (ETDEWEB)

    Gruber, L

    2000-03-31

    Highly charged ions are extracted from an electron beam ion trap and guided to Retrap, a cryogenic Penning trap, where they are merged with laser cooled Be{sup +} ions. The Be{sup +} ions act as a coolant for the hot highly charged ions and their temperature is dropped by about 8 orders of magnitude in a few seconds. Such cold highly charged ions form a strongly coupled nonneutral plasma exhibiting, under such conditions, the aggregation of clusters and crystals. Given the right mixture, these plasmas can be studied as analogues of high density plasmas like white dwarf interiors, and potentially can lead to the development of cold highly charged ion beams for applications in nanotechnology. Due to the virtually non existent Doppler broadening, spectroscopy on highly charged ions can be performed to an unprecedented precision. The density and the temperature of the Be{sup +} plasma were measured and highly charged ions were sympathetically cooled to similar temperatures. Molecular dynamics simulations confirmed the shape, temperature and density of the highly charged ions. Ordered structures were observed in the simulations.

  11. Detection electronics at the Penning trap mass spectrometer PENTATRAP

    Energy Technology Data Exchange (ETDEWEB)

    Doerr, Andreas; Boehm, Christine; Repp, Julia; Roux, Christian; Blaum, Klaus [Physikalisches Institut, Ruprecht-Karls-Universitaet, 69120 Heidelberg (Germany); Max-Planck-Institut fuer Kernphysik, 69117 Heidelberg (Germany); Crespo Lopez-Urrutia, Jose; Eliseev, Sergey; Goncharov, Mikhail [Max-Planck-Institut fuer Kernphysik, 69117 Heidelberg (Germany); Novikov, Yuri [St. Petersburg Nuclear Physics Institute, 188300 Gatchina (Russian Federation); Sturm, Sven [Johannes Gutenberg-Universitaet, Institut fuer Physik, 55099 Mainz (Germany); Ulmer, Stefan [Physikalisches Institut, Ruprecht-Karls-Universitaet, 69120 Heidelberg (Germany); Johannes Gutenberg-Universitaet, Institut fuer Physik, 55099 Mainz (Germany)

    2011-07-01

    The ''five Penning trap'' mass spectrometer PENTATRAP is currently under construction at the Max-Planck-Institut fuer Kernphysik in Heidelberg. Measurements of masses of single stable and long lived highly charged ions with a relative uncertainty on the order of 10{sup -11} are aimed at. The experiment is based on the non-destructive detection of image currents the ion induces in the trap electrodes. Essential part of each detection circuit is an inductance, configured either as a copper wire coil or as a superconducting toroid, in both cases mounted in a copper housing. Since signals are small ({proportional_to}fA), low-noise detection electronics is needed to obtain a sufficient signal-to-noise ratio. Therefore the first amplification stage is a cryogenic GaAs amplifier. Currently, we evaluate the possible use of a SQUID based amplifier. Furthermore, an axial frequency down converter providing a high level of sideband rejection has been set up. Further details on the detection electronics mentioned above will be presented in the poster.

  12. Detection electronics at the Penning-trap mass spectrometer PENTATRAP

    Energy Technology Data Exchange (ETDEWEB)

    Doerr, Andreas; Repp, Julia; Roux, Christian; Blaum, Klaus [Fakultaet fuer Physik und Astronomie, Ruprecht-Karls-Universitaet, 69120 Heidelberg (Germany); Max-Planck-Institut fuer Kernphysik, 69117 Heidelberg (Germany); Boehm, Christine [Fakultaet fuer Physik und Astronomie, Ruprecht-Karls-Universitaet, 69120 Heidelberg (Germany); Max-Planck-Institut fuer Kernphysik, 69117 Heidelberg (Germany); ExtreMe Matter Institute EMMI, Helmholtz Gemeinschaft, 64291 Darmstadt (Germany); Eliseev, Sergey; Goncharov, Mikhail [Max-Planck-Institut fuer Kernphysik, 69117 Heidelberg (Germany); Sturm, Sven [Max-Planck-Institut fuer Kernphysik, 69117 Heidelberg (Germany); Institut fuer Physik, Johannes Gutenberg-Universitaet, 55099 Mainz (Germany); Ulmer, Stefan [Atomic Physics Laboratory, RIKEN Advanced Science Institute, Hirosawa, Wako, Saitama 351-0198 (Japan)

    2012-07-01

    The five Penning-trap mass spectrometer PENTATRAP is currently being built at the Max-Planck-Institut fuer Kernphysik in Heidelberg. Measurements of masses of single stable and long lived highly charged ions with a relative uncertainty on the order of 10{sup -11} are aimed for. The experiment is based on the non-destructive detection of image currents the ion induces in the trap electrodes. Essential part of each detection circuit is a cryogenic high-Q inductance, configured either as a copper wire coil or as a superconducting toroid, in both cases mounted in a copper housing. The following amplification stages consist of cryogenic GaAs FET amplifiers, which provide high input impedances and have low input-related noise densities. With these cryogenic detection systems, the tiny image currents ({proportional_to}fA) induced by a single ion become detectable. The current status of the detection electronics as well as future perspectives are presented in the talk.

  13. Robot Guided 'Pen Skill' Training in Children with Motor Difficulties.

    Science.gov (United States)

    Shire, Katy A; Hill, Liam J B; Snapp-Childs, Winona; Bingham, Geoffrey P; Kountouriotis, Georgios K; Barber, Sally; Mon-Williams, Mark

    2016-01-01

    Motor deficits are linked to a range of negative physical, social and academic consequences. Haptic robotic interventions, based on the principles of sensorimotor learning, have been shown previously to help children with motor problems learn new movements. We therefore examined whether the training benefits of a robotic system would generalise to a standardised test of 'pen-skills', assessed using objective kinematic measures [via the Clinical Kinematic Assessment Tool, CKAT]. A counterbalanced, cross-over design was used in a group of 51 children (37 male, aged 5-11 years) with manual control difficulties. Improved performance on a novel task using the robotic device could be attributed to the intervention but there was no evidence of generalisation to any of the CKAT tasks. The robotic system appears to have the potential to support motor learning, with the technology affording numerous advantages. However, the training regime may need to target particular manual skills (e.g. letter formation) in order to obtain clinically significant improvements in specific skills such as handwriting.

  14. Robot Guided 'Pen Skill' Training in Children with Motor Difficulties.

    Directory of Open Access Journals (Sweden)

    Katy A Shire

    Full Text Available Motor deficits are linked to a range of negative physical, social and academic consequences. Haptic robotic interventions, based on the principles of sensorimotor learning, have been shown previously to help children with motor problems learn new movements. We therefore examined whether the training benefits of a robotic system would generalise to a standardised test of 'pen-skills', assessed using objective kinematic measures [via the Clinical Kinematic Assessment Tool, CKAT]. A counterbalanced, cross-over design was used in a group of 51 children (37 male, aged 5-11 years with manual control difficulties. Improved performance on a novel task using the robotic device could be attributed to the intervention but there was no evidence of generalisation to any of the CKAT tasks. The robotic system appears to have the potential to support motor learning, with the technology affording numerous advantages. However, the training regime may need to target particular manual skills (e.g. letter formation in order to obtain clinically significant improvements in specific skills such as handwriting.

  15. Pen-chant: Acoustic emissions of handwriting and drawing

    Science.gov (United States)

    Seniuk, Andrew G.

    The sounds generated by a writing instrument ('pen-chant') provide a rich and underutilized source of information for pattern recognition. We examine the feasibility of recognition of handwritten cursive text, exclusively through an analysis of acoustic emissions. We design and implement a family of recognizers using a template matching approach, with templates and similarity measures derived variously from: smoothed amplitude signal with fixed resolution, discrete sequence of magnitudes obtained from peaks in the smoothed amplitude signal, and ordered tree obtained from a scale space signal representation. Test results are presented for recognition of isolated lowercase cursive characters and for whole words. We also present qualitative results for recognizing gestures such as circling, scratch-out, check-marks, and hatching. Our first set of results, using samples provided by the author, yield recognition rates of over 70% (alphabet) and 90% (26 words), with a confidence of +/-8%, based solely on acoustic emissions. Our second set of results uses data gathered from nine writers. These results demonstrate that acoustic emissions are a rich source of information, usable---on their own or in conjunction with image-based features---to solve pattern recognition problems. In future work, this approach can be applied to writer identification, handwriting and gesture-based computer input technology, emotion recognition, and temporal analysis of sketches.

  16. Lipid dip-pen nanolithography on self-assembled monolayers

    Science.gov (United States)

    Gavutis, Martynas; Navikas, Vytautas; Rakickas, Tomas; Vaitekonis, Šarūnas; Valiokas, Ramūnas

    2016-02-01

    Dip-pen nanolithography (DPN) with lipids as an ink enables functional micro/nanopatterning on different substrates at high process speeds. However, only a few studies have addressed the influence of the physicochemical properties of the surface on the structure and phase behavior of DPN-printed lipid assemblies. Therefore, by combining the scanning probe and optical imaging techniques in this work we have analyzed lipid microdomain formation on the self-assembled monolayers (SAMs) on gold as well-defined model surfaces that displayed hydrophilic (protein-repellent) or hydrophobic (protein-adhesive) characteristics. We have found that on the tri(ethylene glycol)-terminated SAM the lipid ink transfer was fast (~10-1 μm3 s-1), quasi-linear and it yielded unstable, sparsely packed lipid microspots. Contrary to this, on the methyl-terminated SAM the lipid transfer was ~20 times slower, nonlinear, and the obtained stable dots of ~1 μm in diameter consisted of lipid multilayers. Our comparative analysis indicated that the measured lipid transfer was consistent with the previously reported so-called polymer transfer model (Felts et al 2012, Nanotechnology 23 215301). Further on, by employing the observed distinct contrast in the DPN ink behavior we constructed confined lipid microdomains on pre-patterned SAMs, in which the lipids assembled either into monolayer or multilamellar phases. Such microdomains can be further utilized for lipid membrane mimetics in microarray and lab-on-a-chip device formats.

  17. Robot Guided 'Pen Skill' Training in Children with Motor Difficulties.

    Science.gov (United States)

    Shire, Katy A; Hill, Liam J B; Snapp-Childs, Winona; Bingham, Geoffrey P; Kountouriotis, Georgios K; Barber, Sally; Mon-Williams, Mark

    2016-01-01

    Motor deficits are linked to a range of negative physical, social and academic consequences. Haptic robotic interventions, based on the principles of sensorimotor learning, have been shown previously to help children with motor problems learn new movements. We therefore examined whether the training benefits of a robotic system would generalise to a standardised test of 'pen-skills', assessed using objective kinematic measures [via the Clinical Kinematic Assessment Tool, CKAT]. A counterbalanced, cross-over design was used in a group of 51 children (37 male, aged 5-11 years) with manual control difficulties. Improved performance on a novel task using the robotic device could be attributed to the intervention but there was no evidence of generalisation to any of the CKAT tasks. The robotic system appears to have the potential to support motor learning, with the technology affording numerous advantages. However, the training regime may need to target particular manual skills (e.g. letter formation) in order to obtain clinically significant improvements in specific skills such as handwriting. PMID:26967993

  18. Verifying the accuracy of the TITAN Penning-trap mass spectrometer

    CERN Document Server

    Brodeur, M; Brunner, T; Ettenauer, S; Gallant, A T; Simon, V V; Smith, M J; Lapierre, A; Ringle, R; Delheij, P; Good, M; Lunney, D; Dilling, J

    2011-01-01

    TITAN (TRIUMF's Ion Traps for Atomic and Nuclear science) is an online facility designed to carry out high-precision mass measurements on singly and highly charged radioactive ions. The TITAN Penning trap has been built and optimized in order to perform such measurements with an accuracy in the sub ppb-range. A detailed characterization of the TITAN Penning trap is presented and a new compensation method is derived and demonstrated, verifying the performance in the range of sub-ppb.

  19. Update on insulin treatment for dogs and cats: insulin dosing pens and more

    Directory of Open Access Journals (Sweden)

    Thompson A

    2015-04-01

    Full Text Available Ann Thompson,1 Patty Lathan,2 Linda Fleeman3 1School of Veterinary Science, The University of Queensland, Gatton, QLD, Australia; 2College of Veterinary Medicine Mississippi State University, Starkville, MS, USA; 3Animal Diabetes Australia, Melbourne, VIC, Australia Abstract: Insulin therapy is still the primary therapy for all diabetic dogs and cats. Several insulin options are available for each species, including veterinary registered products and human insulin preparations. The insulin chosen depends on the individual patient's requirements. Intermediate-acting insulin is usually the first choice for dogs, and longer-acting insulin is the first choice for cats. Once the insulin type is chosen, the best method of insulin administration should be considered. Traditionally, insulin vials and syringes have been used, but insulin pen devices have recently entered the veterinary market. Pens have different handling requirements when compared with standard insulin vials including: storage out of the refrigerator for some insulin preparations once pen cartridges are in use; priming of the pen to ensure a full dose of insulin is administered; and holding the pen device in place for several seconds during the injection. Many different types of pen devices are available, with features such as half-unit dosing, large dials for visually impaired people, and memory that can display the last time and dose of insulin administered. Insulin pens come in both reusable and disposable options. Pens have several benefits over syringes, including improved dose accuracy, especially for low insulin doses. Keywords: diabetes, mellitus, canine, feline, NPH, glargine, porcine lente

  20. Mass measurements near the $r$-process path using the Canadian Penning Trap mass spectrometer

    OpenAIRE

    Van Schelt, J.; Lascar, D.; G. Savard; Clark, J. A.; Caldwell, S.; Chaudhuri, A.; Fallis, J.; Greene, J. P.; Levand, 1 A. F.; Li, G.; Sharma, K. S.; Sternberg, M. G.; Sun, T.; Zabransky, B. J.

    2012-01-01

    The masses of 40 neutron-rich nuclides from Z = 51 to 64 were measured at an average precision of $\\delta m/m= 10^{-7}$ using the Canadian Penning Trap mass spectrometer at Argonne National Laboratory. The measurements, of fission fragments from a $^{252}$Cf spontaneous fission source in a helium gas catcher, approach the predicted path of the astrophysical $r$ process. Where overlap exists, this data set is largely consistent with previous measurements from Penning traps, storage rings, and ...

  1. 中性笔绿色设计研究%Green Design Study of Gel Pen

    Institute of Scientific and Technical Information of China (English)

    贝广霞; 何盛; 刘世豪

    2015-01-01

    The problems of environmental pollution are increasingly serious with the widely use of Gel Pen,Gel Pen pollution has become a large white pollution as the same as the plastic bag . This paper analyzes the effects of various component and harm on environment of the abandoned Gel Pen, focusing on the structure of Gel pen , the research proposed a green design method . Through the redesign for the structure of Gel Pen , it is convenient to fill ink into the pen and to replace the damaged pen tip ,which can extend the life of Gel Pen , reduce the waste of resources and environmental pollution, and realize the purpose of environmental protection.%随着中性笔的推广,由此带来的环境污染问题也日益严重,“中性笔污染”已经成为继塑料袋之后的又一大白色污染。在分析废弃中性笔各零部件对环境所带来的影响及危害的基础上,从中性笔本身的设计结构出发,提出了中性笔的绿色设计方案。通过对中性笔芯结构的改进,使笔杆和笔头的连接为密封螺纹连接,大大延长了中性笔芯的使用寿命,达到节能减排,保护环境的目的。

  2. Observer agreement on pen level prevalence of clinical signs in finishing pigs.

    Science.gov (United States)

    Petersen, Henrik Hagbard; Enøe, Claes; Nielsen, Elisabeth Okholm

    2004-07-16

    Four observers performed a standard clinical examination of finisher pigs in two commercial finisher herds. In herd 1,600 finisher pigs in 44 pens were examined. The observers assessed clinical signs of lameness, umbilical hernia and tail bite according to a standardized procedure. The prevalence of the clinical signs was estimated at the pen level. The procedure was repeated after 3 months in another herd, where 730 finisher pigs in 69 pens were examined. The agreement between observer pairs was assessed using prevalence-adjusted bias-adjusted kappa (PABAK) and proportionate-agreement estimates (Ppo) and Pneg). Observer bias was present despite training and standardization of the participating observers. The highest pen level agreement for the observer pairs was found for pens that had one or more pigs with tail bite (PABAK = 0.82-1.00) and umbilical hernia (PABAK = 0.77-1.00). The agreement was fair-to-moderate for identification of pens holding one or more lame pigs (PABAK = 0.27-0.7). In general, the average agreement of observer pairs on absence of clinical signs (Pneg) was higher than for presence (Ppos). The observer bias varied between observer pairs and with the clinical signs. PMID:15325769

  3. A Rapid and Sensitive Assay for the Detection of Benzylpenicillin (PenG in Milk.

    Directory of Open Access Journals (Sweden)

    Anna Pennacchio

    Full Text Available Antibiotics, such as benzyl-penicillin (PenG and cephalosporin, are the most common compounds used in animal therapy. Their massive and illegal use in animal therapy and prophylaxis inevitably causes the presence of traces in foods of animal origin (milk and meat, which creates several problems for human health. With the aim to prevent the negative impact of β-lactam and, in particular, PenG residues present in the milk on customer health, many countries have established maximum residue limits (MRLs. To cope with this problem here, we propose an effective alternative, compared to the analytical methods actually employed, to quantify the presence of penicillin G using the surface plasmon resonance (SPR method. In particular, the PenG molecule was conjugated to a protein carrier to immunize a rabbit and produce polyclonal antibodies (anti-PenG. The produced antibodies were used as molecular recognition elements for the design of a competitive immune-assay for the detection of PenG by SPR experiments. The detection limit of the developed assay was found to be 8.0 pM, a value much lower than the MRL of the EU regulation limit that is fixed at 12 nM. Thus, our results clearly show that this system could be successfully suitable for the accurate and easy determination of PenG.

  4. Breakdown Voltage Research of Penning Gas Mixture in Plasma Display Panel

    Institute of Scientific and Technical Information of China (English)

    Guo Bingang; Liu Chunliang; Song Zhongxiao; Fan Yufeng; Xia Xing; Liu Liu; Fan Duowang

    2005-01-01

    Paschen law and equations, which ignore the influence of the Penning ionization on the electron ionization coefficient (α), are always used as the approximation of the breakdown voltage criterion of the Penning gas mixture in current researches of discharge characteristics of the plasma display panel (PDP). It is doubtful that whether their results match the facts. Based on the Townsend gas self-sustaining discharge condition and the chemical kinetics analysis of the Penning gas mixture discharging in PDP, the empirical equation to describe the breakdown of the Penning gas mixture is given. It is used to calculate the breakdown voltage curves of Ne-Xe/MgO and Ne-Ar/MgO in a testing macroscopic discharge cell of AC-PDP. The effective secondary electron emission coefficients (γeff) of the MgO protective layers are derived by comparing the breakdown voltage curves obtained from the empirical equation with the experimental data of breakdown voltages. In comparison with the results calculated by the Paschen law and the equation which ignore the influence of the Penning ionization on α , the results calculated by the empirical equation have better conformity with experimental data. The empirical equation characterizes the breakdown of the Penning gas mixture in PDP effectively, and gives a convenient way to study its breakdown characteristics and the secondary electron emission behaviors.

  5. RESEARCHES REGARDING THE MAIN REPRODUCTION INDICATORS DETERMINATED IN SOWS, STAND GESTATION PEN TIPE

    Directory of Open Access Journals (Sweden)

    TELEA ADA

    2007-01-01

    Full Text Available Current researches were carried out with the goal to quantisize the lost from the weaning to early gestation at the sows housed in open pen gestation. In this trail wetested two pen types, different not only by size, but also by feeders’ emplacement.The main reproduction indicators that we calculated until the 28 gestation day werethe proportion of sows in heat after weaning, the weaning to estrus interval and thegestation rates. The weaning to estrus interval was about 4 to 7 days, most sowswere in heat in the day 5 and 6 days after weaning. The percent of heat detectionafter weaning was 71.42% for the small pens and 70.71% for the big pens(differences statistically non significant, chi test value was 0.983. The gestation rateat 28 days after insemination was 91.62% for the small pens and 94.72% for thelarge pens (chi test value 0,959, statistically non significant differences. Theoverpopulation for heat induction and after that chipping animals together in thosepens, show that the lost are up to 40.47%, between weaning – day 28 of gestation.

  6. Penning ionization and photoionization electron spectrometry of hydrogen bromide

    International Nuclear Information System (INIS)

    An electron spectrometric study has been performed on HBr using metastable helium and neon atoms as well as helium resonance photons. High resolution electron spectra were obtained for a mixed He (21S, 23S) beam, a pure He(23S) beam, a mixed Ne(3s3P2,3P0) beam, and for HeI VUV light. From the comparison of vibrational populations of HBr+ (X,v') and HBr+ (A,v'), formed by either He* and Ne* Penning ionization (PI) or HeI photoionization, we conclude that HBr+ (X) formation by PI exhibits only little perturbation of HBr potentials, whereas HBr+ (A) formation by PI exhibits substantial bond stretching of HBr due to metastable atom attack preferably from the H end. For He(21S) + HBr the X- and A-state vibrational peak shapes are substantially broader than for the He(23S) + HBr case pointing to an additional, charge exchange interaction (He+ + HBr-) in the entrance channel of the former system which is also responsible for a broad feature found at lower electron energies in the He(21S,23S) induced PI electron spectra. For the first time, we have detected the low energy electrons in both the He(21S) + HBr and He (23S) + HBr spectra, associated with the major mechanism for the formation of Br+ ions: energy transfer to repulsive HBr** Rydberg states, dissociating to H (1s) and autoionizing Br** atoms. The HBr+ (X) 2Π3/2:2Π1/2 fine structure branching ratios vary significantly with the ionizing agent in a similar way as for the isoelectronic, atomic target case krypton. (orig.)

  7. [Histopathology of meibomian gland abnormalities in experimental PenCB intoxicated beagle treated with squalane].

    Science.gov (United States)

    Kohno, T; Ohnishi, Y

    1989-05-01

    In order to examine the effect of squalane to excrete PCB from the intoxicated animals, histopathological studies of Meibomian gland abnormalities were carried out in experimental PenCB (3,4,5,3',4'-pentachlorobiphenyl) intoxicated beagles treated with squalane. All experimental animals except a control group showed characteristic changes of Meibomian glands: dilation of the duct and squamous metaplasia of the alveolar cells. According to the degree of these findings, five stages were divided in the processes of Medibomian gland changes. The PenCB intoxicated dogs initially showed mild pathological changes of the glands and later moderate to severe degrees of findings. In the PenCB intoxicated animals treated with squalane, severe degree of Meibomian gland findings were found in the early stage and mild to moderate abnormalities in the late stage. The concentration of PenCB in blood varied in each animal, and the animals with advanced Medibomian gland abnormalities tended to have high level of PenCB concentration in blood. In conclusion, the effect of squalane to excrete PCB from the intoxicated animals were not determined in this study.

  8. Behavioral, thermoregulatory, and operational aspects of shallow pool pens used in gilts production

    Directory of Open Access Journals (Sweden)

    Heverton Michael Biazzi

    2014-12-01

    Full Text Available This work was conducted to assess behaviors, thermoregulatory, and operational aspects of gilt breeding (Body weight, 25–110 kg whilst the animals were housed in 2-cm deep shallow pool pens (SPP, without the addition of water, compared to the use of fully compact floor pens (TSF during the winter and summer seasons. Commercial female strains for high lean tissue accretion were used, housed in grower/finisher pens for 108 days (11 animals/pen, 1.2 m2/animal. Instantaneous observations of behavior were carried out every 12 min between 7:00 and 19:00 hours throughout the six days of the raising period. At the end of the raising period, the operational aspects of cleaning the facilities were analyzed. A 2 × 2 factorial scheme design was used, with two types of floors and two seasons, with three replicates. The average temperatures in winter and summer were 19.9 ± 2.2°C and 24.5 ± 2.3°C, respectively. The use of SPP reduced aggressive behavior and increased exploratory behavior, increased the time for the daily cleaning, and reduced the time for the final cleaning of the pens.

  9. The Possible Role of Penning Ionization Processes in Planetary Atmospheres

    Directory of Open Access Journals (Sweden)

    Stefano Falcinelli

    2015-03-01

    Full Text Available In this paper we suggest Penning ionization as an important route of formation for ionic species in upper planetary atmospheres. Our goal is to provide relevant tools to researchers working on kinetic models of atmospheric interest, in order to include Penning ionizations in their calculations as fast processes promoting reactions that cannot be neglected. Ions are extremely important for the transmission of radio and satellite signals, and they govern the chemistry of planetary ionospheres. Molecular ions have also been detected in comet tails. In this paper recent experimental results concerning production of simple ionic species of atmospheric interest are presented and discussed. Such results concern the formation of free ions in collisional ionization of H2O, H2S, and NH3 induced by highly excited species (Penning ionization as metastable noble gas atoms. The effect of Penning ionization still has not been considered in the modeling of terrestrial and extraterrestrial objects so far, even, though metastable helium is formed by radiative recombination of He+ ions with electrons. Because helium is the second most abundant element of the universe, Penning ionization of atomic or molecular species by He*(23S1 is plausibly an active route of ionization in relatively dense environments exposed to cosmic rays.

  10. Microstructural control over soluble pentacene deposited by capillary pen printing for organic electronics.

    Science.gov (United States)

    Lee, Wi Hyoung; Min, Honggi; Park, Namwoo; Lee, Junghwi; Seo, Eunsuk; Kang, Boseok; Cho, Kilwon; Lee, Hwa Sung

    2013-08-28

    Research into printing techniques has received special attention for the commercialization of cost-efficient organic electronics. Here, we have developed a capillary pen printing technique to realize a large-area pattern array of organic transistors and systematically investigated self-organization behavior of printed soluble organic semiconductor ink. The capillary pen-printed deposits of organic semiconductor, 6,13-bis(triisopropylsilylethynyl) pentacene (TIPS_PEN), was well-optimized in terms of morphological and microstructural properties by using ink with mixed solvents of chlorobenzene (CB) and 1,2-dichlorobenzene (DCB). Especially, a 1:1 solvent ratio results in the best transistor performances. This result is attributed to the unique evaporation characteristics of the TIPS_PEN deposits where fast evaporation of CB induces a morphological evolution at the initial printed position, and the remaining DCB with slow evaporation rate offers a favorable crystal evolution at the pinned position. Finally, a large-area transistor array was facilely fabricated by drawing organic electrodes and active layers with a versatile capillary pen. Our approach provides an efficient printing technique for fabricating large-area arrays of organic electronics and further suggests a methodology to enhance their performances by microstructural control of the printed organic semiconducting deposits.

  11. Field-scale evaluation of water fluxes and manure solution leaching in feedlot pen soils.

    Science.gov (United States)

    García, Ana R; Maisonnave, Roberto; Massobrio, Marcelo J; Fabrizio de Iorio, Alicia R

    2012-01-01

    Accumulation of beef cattle manure on feedlot pen surfaces generates large amounts of dissolved solutes that can be mobilized by water fluxes, affecting surface and groundwater quality. Our objective was to examine the long-term impacts of a beef cattle feeding operation on water fluxes and manure leaching in feedlot pens located on sandy loam soils of the subhumid Sandy Pampa region in Argentina. Bulk density, gravimetric moisture content, and chloride concentration were quantified. Rain simulation trials were performed to estimate infiltration and runoff rates. Using chloride ion as a tracer, profile analysis techniques were applied to estimate the soil moisture flux and manure conservative chemical components leaching rates. An organic stratum was found over the surface of the pen soil, separated from the underlying soil by a highly compacted thin layer (the manure-soil interface). The soil beneath the organic layer showed greater bulk density in the A horizon than in the control soil and had greater moisture content. Greater concentrations of chloride were found as a consequence of the partial sealing of the manure-soil interface. Surface runoff was the dominant process in the feedlot pen soil, whereas infiltration was the main process in control soil. Soil moisture flux beneath pens decreased substantially after 15 yr of activity. The estimated minimum leaching rate of chloride was 13 times faster than the estimated soil moisture flux. This difference suggests that chloride ions are not exclusively transported by advective flow under our conditions but also by solute diffusion and preferential flow. PMID:23099951

  12. Classical calculation of relativistic frequency-shifts in an ideal Penning trap

    CERN Document Server

    Ketter, Jochen; Höcker, Martin; Schuh, Marc; Streubel, Sebastian; Blaum, Klaus

    2013-01-01

    The ideal Penning trap consists of a uniform magnetic field and an electrostatic quadrupole potential. In the classical low-energy limit, the three characteristic eigenfrequencies of a charged particle trapped in this configuration do not depend on the amplitudes of the three eigenmotions. No matter how accurate the experimental realization of the ideal Penning trap, its harmonicity is ultimately compromised by special relativity. Using a classical formalism of first-order perturbation theory, we calculate the relativistic frequency-shifts associated with the motional degrees of freedom for a spinless particle stored in an ideal Penning trap, and we compare the results with the simple but surprisingly accurate model of relativistic mass-increase.

  13. Séminaire sur les Pensées de Pascal

    OpenAIRE

    Descotes, Dominique

    2016-01-01

    À l’initiative de Laurent Thirouin, Antony McKenna et Dominique Descotes, le CIBP organise un séminaire consacré aux Pensées. Projet du séminaire Son objet est un examen méthodique et ordonné des fragments des Pensées, en vue de constituer un état des sources et des principaux commentaires, et de faire le point sur les interprétations majeures dont les textes ont fait l’objet. Le séminaire procédera à l’examen par ordre des fragments des Pensées, sans chercher à passer rapidement aux plus con...

  14. Efficacy of monensin against turkey coccidiosis in laboratory and floor-pen experiments.

    Science.gov (United States)

    Anderson, W I; Reid, W M; McDougald, L R

    1976-01-01

    Monensin at 60, 80, or 100 ppm in feed reduced mortality and lesion scores while protecting against weight loss of turkeys infected with the major pathogenic species: Eimeria adenoides, E. meleagrimitis, and E. gallopavonis. With single and mixed infections in battery-cage experiments, the death rate of unmedicated turkey poults was 33-75%. Weight gains were significantly (P is less than or equal to 0.05) better with 100 ppm monensin than 60 ppm, as were also lesion scores. Under floor-pen conditions there were no significant differences among monensin treatments. Moisture content of the litter was significantly lower in all monensin-medicated pens (40%, compared with 52% moisture in pens of unmedicated controls).

  15. Cost minimization analysis of different growth hormone pen devices based on time-and-motion simulations

    Directory of Open Access Journals (Sweden)

    Kim Jaewhan

    2010-04-01

    Full Text Available Abstract Background Numerous pen devices are available to administer recombinant Human Growth Hormone (rhGH, and both patients and health plans have varying issues to consider when selecting a particular product and device for daily use. Therefore, the present study utilized multi-dimensional product analysis to assess potential time involvement, required weekly administration steps, and utilization costs relative to daily rhGH administration. Methods Study objectives were to conduct 1 Time-and-Motion (TM simulations in a randomized block design that allowed time and steps comparisons related to rhGH preparation, administration and storage, and 2 a Cost Minimization Analysis (CMA relative to opportunity and supply costs. Nurses naïve to rhGH administration and devices were recruited to evaluate four rhGH pen devices (2 in liquid form, 2 requiring reconstitution via TM simulations. Five videotaped and timed trials for each product were evaluated based on: 1 Learning (initial use instructions, 2 Preparation (arrange device for use, 3 Administration (actual simulation manikin injection, and 4 Storage (maintain product viability between doses, in addition to assessment of steps required for weekly use. The CMA applied micro-costing techniques related to opportunity costs for caregivers (categorized as wages, non-drug medical supplies, and drug product costs. Results Norditropin® NordiFlex and Norditropin® NordiPen (NNF and NNP, Novo Nordisk, Inc., Bagsværd, Denmark took less weekly Total Time (p ® Pen (GTP, Pfizer, Inc, New York, New York or HumatroPen® (HTP, Eli Lilly and Company, Indianapolis, Indiana. Time savings were directly related to differences in new package Preparation times (NNF (1.35 minutes, NNP (2.48 minutes GTP (4.11 minutes, HTP (8.64 minutes, p Conclusions Time-and-motion simulation data used to support a micro-cost analysis demonstrated that the pen device with the greater time demand has highest net costs.

  16. EpiPen epidemic: suggestions for rational prescribing in childhood food allergy.

    Science.gov (United States)

    Kemp, A S

    2003-07-01

    There has been a marked increase in community concerns of the risk of food induced anaphylaxis in children and a consequent increase in the provision of the self or carer injectable epinephrine (EpiPen) (CSL Ltd, Parkville, Victoria, Australia)). The Australian use of EpiPens in children under 10 years has increased by 300% over 5 years with a crude rate of EpiPen provision of 1 per 544 Australian children aged under 10 years. However, the risk of a fatal reaction to food, particularly in preschool children, is remote (in Australia, an estimated one fatality in 30 years in the under 5-year-old population and two deaths in 10 years in the entire child population). It is therefore important to provide a perspective on the risk of death from food induced anaphylactic to parents and carers in view of the anxiety generated on this issue. The indications for provision of an EpiPen to children are not well defined. Six risk factors, which can be considered in evaluating the risk of a life-threatening reaction (age over 5 years; a history of respiratory tract involvement with the initial or subsequent reactions; a history of asthma requiring preventer medication; peanut or tree nut sensitivity; reactions induced by traces or small amounts of allergen; a strongly positive skin prick test) are proposed. It is suggested that the greater the number that are positive, the lower the threshold for provision of an EpiPen. In addition, instruction in EpiPen administration and the provision of both a clear and simple anaphylaxis action plan and a rational perspective on the remote risk of death is just as important as the provision of the device itself.

  17. Electric and magnetic field optimization procedure for Penning trap mass spectrometers

    CERN Document Server

    Beck, D; Bollen, G; Delahaye, P; George, S; Guénaut, C; Herfurth, F; Herlert, A; Lunney, D; Schweikhard, L; Yazidjian, C

    2009-01-01

    Significant systematic errors in high-precision Penning trap mass spectrometry can result from electric and magnetic field imperfections. An experimental procedure to minimize these uncertainties is presented for the on-line Penning trap mass spectrometer ISOLTRAP, located at ISOLDE/CERN. The deviations from the ideal magnetic and electric fields are probed by measuring the cyclotron frequency and the reduced cyclotron frequency, respectively, of stored ions as a function of the time between the ejection of ions from the preparation trap and their capture in the precision trap, which influences the energy of their axial motion. The correction parameters are adjusted to minimize the frequency shifts.

  18. From Pen-and-Paper Sketches to Prototypes: The Advanced Interaction Design Environment

    DEFF Research Database (Denmark)

    Störrle, Harald

    2014-01-01

    Pen and paper is still the best tool for sketching GUIs. How-ever, sketches cannot be executed, at best we have facilitated or animated scenarios. The Advanced User Interaction Environment facilitates turn-ing hand-drawn sketches into executable prototypes.......Pen and paper is still the best tool for sketching GUIs. How-ever, sketches cannot be executed, at best we have facilitated or animated scenarios. The Advanced User Interaction Environment facilitates turn-ing hand-drawn sketches into executable prototypes....

  19. Assessment of Pen Branch delta and corridor vegetation changes using multispectral scanner data 1992--1994

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-01-01

    Airborne multispectral scanner data were used to monitor natural succession of wetland vegetation species over a three-year period from 1992 through 1994 for Pen Branch on the Savannah River Site in South Carolina. Image processing techniques were used to identify and measure wetland vegetation communities in the lower portion of the Pen Branch corridor and delta. The study provided a reliable means for monitoring medium- and large-scale changes in a diverse environment. Findings from the study will be used to support decisions regarding remediation efforts following the cessation of cooling water discharge from K reactor at the Department of Energy`s Savannah River Site in South Carolina.

  20. CrossRef Space-charge effects in Penning ion traps

    CERN Document Server

    Porobić, T; Breitenfeldt, M; Couratin, C; Finlay, P; Knecht, A; Fabian, X; Friedag, P; Fléchard, X; Liénard, E; Ban, G; Zákoucký, D; Soti, G; Van Gorp, S; Weinheimer, Ch; Wursten, E; Severijns, N

    2015-01-01

    The influence of space-charge on ion cyclotron resonances and magnetron eigenfrequency in a gas-filled Penning ion trap has been investigated. Off-line measurements with View the MathML source using the cooling trap of the WITCH retardation spectrometer-based setup at ISOLDE/CERN were performed. Experimental ion cyclotron resonances were compared with ab initio Coulomb simulations and found to be in agreement. As an important systematic effect of the WITCH experiment, the magnetron eigenfrequency of the ion cloud was studied under increasing space-charge conditions. Finally, the helium buffer gas pressure in the Penning trap was determined by comparing experimental cooling rates with simulations.

  1. Development of a highly-sensitive Penning ionization electron spectrometer using the magnetic bottle effect

    Energy Technology Data Exchange (ETDEWEB)

    Ota, Masahiro; Ishiguro, Yuki; Nakajima, Yutaro; Miyauchi, Naoya; Yamakita, Yoshihiro, E-mail: yamakita@uec.ac.jp [Department of Engineering Science, Graduate School of Informatics and Engineering The University of Electro-Communications 1-5-1 Chofugaoka, Chofu, Tokyo 182-8585 (Japan)

    2016-02-01

    This paper reports on a highly-sensitive retarding-type electron spectrometer for a continuous source of electrons, in which the electron collection efficiency is increased by utilizing the magnetic bottle effect. This study demonstrates an application to Penning ionization electron spectroscopy using collisional ionization with metastable He*(2{sup 3}S) atoms. Technical details and performances of the instrument are presented. This spectrometer can be used for studies of functional molecules and assemblies, and exterior electron densities are expected to be selectively observed by the Penning ionization.

  2. A Survey of Pen name semantic Applications in Rumis Sonnets (Ghazals

    Directory of Open Access Journals (Sweden)

    Zohre AhmadiPoor anari

    2015-04-01

    Full Text Available Abstract The pen name in sonnet is the poet’s poetic name which most of the poets mention it in their verses. Jalāl ad-Dīn Muhammad Balkhī also known as Jalāl ad-Dīn Rumi lived in 13th-century was a Persian Moslem poet, theologian, and Sufi mystic. He has written more than 3229 sonnets and dedicated to Shams Tabrizi. Thus mentioned, names such “Shams”, “Shams od-Din” and “Shams al-Haq” in the ending lines of his sonnets.    One of the points which could be studied about pen name is study of theme or concepts which are mentioned alongside that. Entirely it has been said that the same theme which comes with the pen name “Shams” in 992 sonnets. In this study, we pay attention to mentioning the poets desired name which is not necessarily the pen name in Rumis’ sonnets, what theme does it carry and what is relationship of it with the previous lines?    Themes which the poets apply in their sonnets beside pen name is mostly what that has been mentioned in the previous lines. However, in times the concept mentioned along side with the pen name is independent from the sonnet concepts, mostly eulogy. Studying Hafiz and Saadi sonnets shows that the most important themes existing are: love declaration, advice, eulogizing and sometimes a mischievous concept.    Rumis’ sonnets are lover-based. Therefore, there is much talk of the lover in the whole sonnet. But in other poet’s sonnets, the lover (the poet is the main theme is the sonnet. The poet may find a way to praise his own poem or stays in his dreamy world and focuses on the romantic feelings. Considering the fact that unlike other poets Rumi has not mentioned his own pen name but his lover “Shams”, the study focuses on the themes which are mentioned by the pen name “Shams” as the following: 1-Eulogy: One third of the Shams pen names are eulogies. The sufist approach has given the lines a special color. The similes and metaphors used for him are heavenly and

  3. RESEARCHES REGARDING THE MAIN REPRODUCTION INDICATORS DETERMINATED IN SOWS, STAND GESTATION PEN TIPE

    OpenAIRE

    TELEA ADA; IVAN ALEXANDRA; PANDUR IOANA; UNTARU RAMONA; N. PĂCALĂ

    2013-01-01

    Current researches were carried out with the goal to quantisize the lost from the weaning to early gestation at the sows housed in open pen gestation. In this trail we tested two pen types, different not only by size, but also by feeders’ emplacement. The main reproduction indicators that we calculated until the 28 gestation day were the proportion of sows in heat after weaning, the weaning to estrus interval and the gestation rates. The weaning to estrus interval was about 4 to 7 days, most ...

  4. Psychometric Assessment of the Injection Pen Assessment Questionnaire (IPAQ): measuring ease of use and preference with injection pens for human growth hormone

    OpenAIRE

    Pleil Andreas M; Kimel Miriam; McCormack Julie; Rajicic Natasa; Hey-Hadavi Judith

    2012-01-01

    Abstract Purpose To examine the psychometric properties of the Injection Pen Assessment Questionnaire (IPAQ) including the following: 1) item and scale characteristics (e.g., frequencies, item distributions, and factor structure), 2) reliability, and 3) validity. Methods Focus groups and one-on-one dyad interviews guided the development of the IPAQ. The IPAQ was subsequently tested in 136 parent–child dyads in a Phase 3, 2-month, open-label, multicenter trial for a new Genotropin® disposable ...

  5. The Comparison of the Rheological Behaviour of PET and PEN%PEN和PET的流变性能

    Institute of Scientific and Technical Information of China (English)

    李文刚; 罗琳琳; 路海冰; 袁雯

    2011-01-01

    聚2,6-萘二甲酸乙二醇酯(PEN)是一种结构上与PET非常相近的新型聚酯,近年来逐渐成为研究的热点.利用哈克流变仪对PET和PEN在不同温度及剪切速率下的流变性能进行了研究.流变行为研究表明:PEN的剪切黏度随剪切速度的增加而减小,属于典型的非牛顿流体;从流变曲线上来看,随着剪切速率的改变,PEN的剪切黏度的变化要小;而黏流活化能则表明:PEN剪切黏度的变化对温度的变化更敏感,这就意味着PEN对加工工艺具有更高的要求.%Poly (ethylene 2,6-naphthalate) (PEN) was a new kind of polyester with the structure like poly (ethylene terephthalate) (PET). Because of the double benzene nucleus in PEN,PEN products had high strength and modulus,stable dimension and thermal stability and so on. In recent years, PEN was gradually becoming a research focus. The results of rheology showed that the apparent viscosity of PEN decreased with the increase of shearing speed, so PEN belongs to the typical Non-Newton Fluid. The apparent viscosity of PEN was smaller dependent on shear rate than PET from the flow curve. The low activation energy indicated that the change of apparent viscosity of PEN was more sensitive to the changes of temperature, so higher requirements was needed for the processing of PEN.

  6. Cascaded Energy Transfer for Efficient Broad-Band Pumping of High Quality, Micro Lasers

    Energy Technology Data Exchange (ETDEWEB)

    Rotschild, Carmel; Tomes, M.; Mendoza, H.; Andrew, T. L.; Swager, Timothy M.; Carmon, T.; Baldo, Marc

    2011-05-24

    Micro-ring lasers that exhibit a quality factor (Q) larger than 5.2 × 10{sup 6} with a direct-illumination, non-resonant pump are demonstrated. The micro-rings are coated with three organic dyes forming a cascaded energy-transfer, which reduces material-losses by a factor larger than 10{sup 4}, transforming incoherent light to coherent light with high quantum-efficiency. The operating principle is general and can enable fully integrated on-chip, high-Q micro-lasers.

  7. A new method for detemining the Angstrom turbidity coefficient from broad-band filter measurements.

    OpenAIRE

    Utrillas Esteban, Mª Pilar; Pedrós Esteban, Roberto; Martínez Lozano, José Antonio; Tena Sangüesa, Fernando

    2000-01-01

    In this work, a new method for determining Ångström turbidity coefficients is presented. This method is based on broadband filter irradiance measurements. By combining measurements obtained with different filters it is possible to obtain a single value of the turbidity coefficient representative of the whole measurement range of the pyrheliometer. The results provided by this new method are compared with the original Ångström method and turbidity coefficient values derived by spectroradiometr...

  8. Nonlinear optics with broad-band lasers: Progress report, July 15, 1987-April 14, 1988

    International Nuclear Information System (INIS)

    During this reporting period several important results were obtained on the fluctuation dynamics of both continuous-wave (cw) and pulsed dye lasers, as well as their effects in certain nonlinear optical processes: (1) A new method discovered for producing optical pulses with broad bandwidths (5 GHz) and smooth, slowly varying amplitude. The bandwidth is determined purely by phase fluctuations. (2) A theoretical treatment of pulsed dye lasers was developed to explain intensity autocorrelation measurements. (3) The effects of laser bandwidth on the resonance fluorescence spectrum of a two-level atom were calculated. (4) The source of mode intensity fluctuations in a multimode, cw dye laser were shown, both experimentally and theoretically, to be caused by deterministic chaos, rather than quantum noise as had been previously assumed in the literature

  9. Broad-band Gausssian noise is most effective in improving motor performance and is most pleasant

    Directory of Open Access Journals (Sweden)

    Carlos eTrenado

    2014-02-01

    Full Text Available Modern attempts to improve human performance focus on stochastic resonance (SR. SR is a phenomenon in nonlinear systems characterized by a response increase of the system induced by a particular level of input noise. Recently, we reported that an optimum level of 0-15 Hz Gaussian noise applied to the human index finger improved static isometric force compensation. A possible explanation was a better sensorimotor integration caused by increase in sensitivity of peripheral receptors and/or of internal SR. The present study in 10 subjects compares SR effects in the performance of the same motor task and on pleasantness, by applying three Gaussian noises chosen on the sensitivity of the fingertip receptors (0-15 Hz mostly for Merkel receptors, 250-300 Hz for Pacini corpuscules and 0-300 Hz for all. We document that only the 0-300 Hz noise induced SR effect during the transitory phase of the task. In contrast, the motor performance was improved during the stationary phase for all three noise frequency bandwidths. This improvement was stronger for 0-300 Hz and 250-300 Hz than for 0-15 Hz noise. Further, we found higher degree of pleasantness for 0-300 Hz and 250-300 Hz noise bandwidths than for 0-15 Hz. Thus, we show that the most appropriate Gaussian noise that could be used in haptic gloves is the 0-300 Hz, as it improved motor performance during both stationary and transitory phases. In addition, this noise had the highest degree of pleasantness and thus reveals that the glabrous skin can also forward pleasant sensations. These new findings provide worthy information for neurorehabilitation.

  10. Molecular response of nasal mucosa to therapeutic exposure to broad-band ultraviolet radiation.

    Science.gov (United States)

    Mitchell, David; Paniker, Lakshmi; Sanchez, Guillermo; Bella, Zsolt; Garaczi, Edina; Szell, Marta; Hamid, Qutayba; Kemeny, Lajos; Koreck, Andrea

    2010-01-01

    Ultraviolet radiation (UVR) phototherapy is a promising new treatment for inflammatory airway diseases. However, the potential carcinogenic risks associated with this treatment are not well understood. UV-specific DNA photoproducts were used as biomarkers to address this issue. Radioimmunoassay was used to quantify cyclobutane pyrimidine dimers (CPDs) and (6-4) photoproducts in DNA purified from two milieus: nasal mucosa samples from subjects exposed to intranasal phototherapy and human airway (EpiAirway) and human skin (EpiDerm) tissue models. Immunohistochemistry was used to detect CPD formation and persistence in human nasal biopsies and human tissue models. In subjects exposed to broadband ultraviolet radiation, DNA damage frequencies were determined prior to as well as immediately after treatment and at increasing times post-treatment. We observed significant levels of DNA damage immediately after treatment and efficient removal of the damage within a few days. No residual damage was observed in human subjects exposed to multiple UVB treatments several weeks after the last treatment. To better understand the molecular response of the nasal epithelium to DNA damage, parallel experiments were conducted in EpiAirway and EpiDerm model systems. Repair rates in these two tissues were very similar and comparable to that observed in human skin. The data suggest that the UV-induced DNA damage response of respiratory epithelia is very similar to that of the human epidermis and that nasal mucosa is able to efficiently repair UVB induced DNA damage.

  11. Towards doubling solar harvests using wide-angle, broad-band microfluidic beam steering arrays.

    Science.gov (United States)

    DiDomenico, Leo D

    2015-11-30

    This paper introduces Microfluidic Beam Steering (MBS), which is a new technique for electronically steering light having multiple octaves of bandwidth, any polarization state and incidence from any direction of the sky without significant restrictions due to physical area, optical loss and power handling capacity. It is based on optical elements comprising both transparent solids and electronically controllable fluids to control Total Internal Reflection (TIR), refraction and/or diffraction from micro-structured surfaces within a transparent solid. A TIR-based MBS is discussed in the context of solar energy and its potential to significantly increase annual energy harvests from solar arrays situated on fixed areas like roofs. The advantages and challenges associated with analog and digital MBS systems are discussed and early-stage MBS hardware is demonstrated. Finally, an analytic model of sun-tracking is provided to formally establish the potential for MBS to increase annual solar energy harvests by approximately 45% more than conventional 0-Degree Of Freedom (0-DOF) solar arrays, 62% more than 1-DOF arrays and 233% more than 2-DOF arrays, all at 20% atmospheric aerosol scattering. PMID:26698790

  12. Secure communication in fiber optic systems via transmission of broad-band optical noise.

    Science.gov (United States)

    Buskila, O; Eyal, A; Shtaif, M

    2008-03-01

    We propose a new scheme for data encryption in the physical layer. Our scheme is based on the distribution of a broadband optical noise-like signal between Alice and Bob. The broadband signal is used for the establishment of a secret key that can be used for the secure transmission of information by using the one-time-pad method. We characterize the proposed scheme and study its applicability to the existing fiber-optics communications infrastructure.

  13. Optimized Variational 1D Boussinesq Modelling for broad-band waves over flat bottom

    NARCIS (Netherlands)

    Lakhturov, I.; Adytia, D.; Groesen, van E.

    2012-01-01

    The Variational Boussinesq Model (VBM) for waves above a layer of ideal fluid conserves mass, momentum, energy, and has decreased dimensionality compared to the full problem. It is derived from the Hamiltonian formulation via an approximation of the kinetic energy, and can provide approximate disper

  14. Optimized variational Boussinesq modelling; part 1: Broad-band waves over flat bottom

    NARCIS (Netherlands)

    Lakhturov, I.; Groesen, van E.

    2010-01-01

    The Variational Boussinesq Model (VBM) for waves above a layer of ideal fluid conserves mass, momentum, energy, and has decreased dimensionality compared to the full problem. It is derived from the Hamiltonian formulation via an approximation of the kinetic energy, and can provide approximate disper

  15. Happy Birthday Swift: Ultra-long GRB141121A and its broad-band Afterglow

    CERN Document Server

    Cucchiara, A; Corsi, A; Cenko, S B; Perley, D A; Marshall, A Lien F E; Pagani, C; Toy, V L; Capone, J I; Frail, D A; Horesh, A; Modjaz, M; Butler, N R; Littlejohns, O M; Watson, A M; Kutyrev, A S; Lee, W H; Richer, M G; Klein, C R; Fox, O D; Prochaska, J X; Bloom, J S; Troja, E; Ramirez-Ruiz, E; de Diego, J A; Georgiev, L; Gonzalez, J; Roman-Zuniga, C G; Gehrels, N; Moseley, H

    2015-01-01

    We present our extensive observational campaign on the Swift-discovered GRB141121A, al- most ten years after its launch. Our observations covers radio through X-rays, and extends for more than 30 days after discovery. The prompt phase of GRB 141121A lasted 1410 s and, at the derived redshift of z = 1.469, the isotropic energy is E{\\gamma},iso = 8.0x10^52 erg. Due to the long prompt duration, GRB141121A falls into the recently discovered class of UL-GRBs. Peculiar features of this burst are a flat early-time optical light curve and a radio-to-X-ray rebrightening around 3 days after the burst. The latter is followed by a steep optical-to-X-ray decay and a much shallower radio fading. We analyze GRB 141121A in the context of the standard forward-reverse shock (FS,RS) scenario and we disentangle the FS and RS contributions. Finally, we comment on the puzzling early-time (t ~3 d) behavior of GRB 141121A, and suggest that its interpretation may require a two-component jet model. Overall, our analysis confirms that ...

  16. BROAD-BAND EMISSION OF Cr3+ IN MgAl2O4 SPINEL

    OpenAIRE

    Strek, W.; Dere, P.; Jezowska-Trzebiatowska, B.

    1987-01-01

    The double luminescence behaviour of Cr (III) in synthetic MgAl2O4 spinel was observed. The nature of such a behaviour is investigated by means the time-resolved luminescence studies at different excitation wavelengths. It is shown that the broad-broad emission observed in synthetic spinel is due to the spin-allowed 4T2 → 4A2 fluorescence transition.

  17. The Application Analysis of Concurrent Multipath Transfer over Broad-band Network

    Institute of Scientific and Technical Information of China (English)

    赵欢欢

    2016-01-01

    In the network for data transmission using CMT, there are multiple paths to choose, and the time delay of each path is not the same, there is a certain issue packet out-of-order. This article studied and analyzed the packet transmission in the sender, for each path assigned specific packet sequence number, in order to reduce the random sequence problem, improve the efficien-cy of network transmission. In the network for data transmission using CMT, there are multiple paths to choose, and the time de-lay of each path is not the same, there is a certain issue packet out-of-order. This article studied and analyzed the packet transmis-sion in the sender, for each path assigned specific packet sequence number, in order to reduce the random sequence problem, im-prove the efficiency of network transmission.

  18. Broad-band Gaussian noise is most effective in improving motor performance and is most pleasant.

    Science.gov (United States)

    Trenado, Carlos; Mikulić, Areh; Manjarrez, Elias; Mendez-Balbuena, Ignacio; Schulte-Mönting, Jürgen; Huethe, Frank; Hepp-Reymond, Marie-Claude; Kristeva, Rumyana

    2014-01-01

    Modern attempts to improve human performance focus on stochastic resonance (SR). SR is a phenomenon in non-linear systems characterized by a response increase of the system induced by a particular level of input noise. Recently, we reported that an optimum level of 0-15 Hz Gaussian noise applied to the human index finger improved static isometric force compensation. A possible explanation was a better sensorimotor integration caused by increase in sensitivity of peripheral receptors and/or of internal SR. The present study in 10 subjects compares SR effects in the performance of the same motor task and on pleasantness, by applying three Gaussian noises chosen on the sensitivity of the fingertip receptors (0-15 Hz mostly for Merkel receptors, 250-300 Hz for Pacini corpuscles and 0-300 Hz for all). We document that only the 0-300 Hz noise induced SR effect during the transitory phase of the task. In contrast, the motor performance was improved during the stationary phase for all three noise frequency bandwidths. This improvement was stronger for 0-300 Hz and 250-300 Hz than for 0-15 Hz noise. Further, we found higher degree of pleasantness for 0-300 Hz and 250-300 Hz noise bandwidths than for 0-15 Hz. Thus, we show that the most appropriate Gaussian noise that could be used in haptic gloves is the 0-300 Hz, as it improved motor performance during both stationary and transitory phases. In addition, this noise had the highest degree of pleasantness and thus reveals that the glabrous skin can also forward pleasant sensations. PMID:24550806

  19. Multiplexed Volume Bragg Gratings in Narrowand Broad-band Spectral Systems: Analysis and Application

    Science.gov (United States)

    Ingersoll, Gregory B.

    Volume Bragg gratings (VBGs) are important holographic optical elements in many spectral systems. Using multiple volume gratings, whether multiplexed or arranged sequentially, provides advantages to many types of systems in overall efficiency, dispersion performance, flexibility of design, etc. However, the use of multiple gratings---particularly when the gratings are multiplexed in a single holographic optical element (HOE)---is subject to inter-grating coupling effects that ultimately limit system performance. Analyzing these coupling effects requires a more complex mathematical model than the straightforward analysis of a single volume grating. We present a matrix-based algorithm for determining diffraction efficiencies of significant coupled waves in these multiplexed grating holographic optical elements (HOEs). Several carefully constructed experiments with spectrally multiplexed gratings in dichromated gelatin verify our conclusions. Applications of this theory to broad- and narrow-band systems are explored in detailed simulations. Broadband systems include spectrum splitters for diverse-bandgap photovoltaic (PV) cells. Volume Bragg gratings can serve as effective spectrum splitters, but the inherent dispersion of a VBG can be detrimental given a broad-spectrum input. The performance of a holographic spectrum splitter element can be improved by utilizing multiple volume gratings, each operating in a slightly different spectral band. However, care must be taken to avoid inter-grating coupling effects that limit ultimate performance. We explore broadband multi-grating holographic optical elements (HOEs) in sandwiched arrangements where individual single-grating HOEs are placed in series, and in multiplexed arrangements where multiple gratings are recorded in a single HOE. Particle swarm optimization (PSO) is used to tailor these systems to the solar spectrum taking into account both efficiency and dispersion. Both multiplexed and sandwiched two-grating systems exhibit performance improvements over single-grating solutions, especially when reduced dispersion is required. Dispersion performance can be further improved by employing more than two VBGs in the spectrum splitter, but efficiency is compromised by additional cross-coupling effects. Narrow-band applications of the multi-grating theory include spectral beam combining (SBC) systems. SBC systems utilizing multiple VBGs must be carefully analyzed to maximize channel density and efficiency, and thus output radiance. This analysis grows increasingly difficult as the number of channels in the system increases, and heuristic optimization techniques (e.g. PSO) are again useful tools for exploring the limits of these systems. We explore three classes of multi-grating SBC systems: "cascaded" where each grating adds a new channel to the system in sequence, "sandwiched" where several individual gratings are placed together and all channels enter the system at the same facet, and "multiplexed" where all of the gratings occupy the same holographic optical element (HOE). Loss mechanisms differ among these three basic classes, and the optimization algorithm shows that the highest channel density for a given minimum efficiency and fixed operating bandwidth is achieved for a cascaded-grating system. The multiplexed-grating system exhibits the lowest channel density under that same constraints but has the distinct advantage of being realized by a single HOE. For a particular application, one must weigh channel density and efficiency versus system complexity when choosing among these basic classes of SBC system. Additionally, one may need to consider the effects of finite-width input beams. As input beam radius is reduced, angular clipping effects begin to dominate over spectral interference and crosstalk effects, limiting all three classes of SBC systems in a similar manner.

  20. Development of a large reactive silencer to attenuate mid frequency broad band sound: a case study

    Energy Technology Data Exchange (ETDEWEB)

    Sacks, M. P.; Kane, J.

    1996-08-01

    Development of a large reactive silencer, modifying the pollution control system of a fluid catalytic cracking unit at an east coast oil refinery, was described. The modification was necessitated by complaints from nearby residents, and company determination that sound levels in the community could reach 75dBA to 80 dBA under frequent downwind conditions in an otherwise quiet residential area. Design, construction and testing of a scale model, static testing of the full size silencer prior to delivery and installation, and preliminary in situ results were reviewed and discussed. 1 ref., 5 figs.

  1. Passive, broad-band seismic measurements for geothermal exploration : The GAPSS experiment

    Science.gov (United States)

    Saccorotti, Gilberto; Piccinini, Davide; Zupo, Maria; Mazzarini, Francesco; Cauchie, Lena; Chiarabba, Claudio; Piana Agostinetti, Nicola

    2014-05-01

    Passive seismological imaging techniques based on either transient (earthquakes) or sustained (background noise) signals can provide detailed descriptions of subsurface attributes as seismic velocity, attenuation, and anisotropy. However, the correspondence between these parameters and the physical properties of crustal fluids is still ambiguous. Moreover, the resolving capabilities and condition of applicability of emerging techniques such as the Ambient Noise Tomography are still to be investigated thoroughly. Following these arguments, a specific project (GAPSS-Geothermal Area Passive Seismic Sources) was planned, in order to test passive exploration methods on a well-known geothermal area, namely the Larderello-Travale Geothermal Field (LTGF). This geothermal area is located in the western part of Tuscany (Italy), and it is the most ancient geothermal power field of the world. Heat flow in this area can reach local peaks of 1000 mW/m3. The deep explorations in this area showed a deeper reservoir (3000 to 4000 m depth) located within the metamorphic rocks in the contact aureole of the Pliocene-Quaternary granites; it is characterized by a wide negative gravimetric anomaly, interpreted as partially molten granite at temperatures of 800°C. From seismic surveys the K-marker K (pressurized horizons) was found at depths between 3 and 7 km. The structural grain of the geothermal field is characterized by N-W trending and N-E dipping normal faults whose activity lasts since the Pliocene. GAPSS lasted from early May, 2012, through October, 2013. It consisted of up to 20 temporary seismic stations, complemented by two permanent stations from the National Seismic Network of Italy. The resulting array has an aperture of about 50 Km, with station spacings between 2 and 50 km. Stations are equipped with either broadband (40s and 120s) or intermediate-period (5s), 3-components seismometers. LTGF is seismically active. During the first 10 months of measurements, we located more than 1000 earthquakes, with a peak rate of up to 40 shocks/day. Preliminary results from analysis of these signals include: (i) The analysis of clustered microearthquakes likely resulting from re-injection processes, thus allowing for the detailed determination of the temporal and magnitude distributions which are likely indicators of induced seismicity; (ii) Seismic noise analysis for deriving the 0.05-0.5 Hz dispersive properties of the noise wavefield, which are inverted for shear-wave velocity profiles; (iii) The analysis of Shear-Wave-Splitting from local earthquake data, from which we found an anisotropic layer which correlates well with the K-horizon; (iv) Local-earthquake Travel-Time tomography for both P- and S-wave velocities, and (v) telesismic receiver function aimed at determining the high-resolution (body. In this manner, we are able to precisely locate the source of the seismic anisotropy at depth. In this communication we present preliminary results from these analysis, I turn discussing their applicability to the exploration of geothermal resources.

  2. Advanced broad-band solid-state supermirror polarizers for cold neutrons

    CERN Document Server

    Petukhov, A K; Bigault, T; Courtois, P; Jullien, D; Soldner, T

    2016-01-01

    An ideal solid-state supermirror (SM) neutron polarizer assumes total reflection of neutrons from the SM coating for one spin-component and total absorption for the other, thus providing a perfectly polarized neutron beam at the exit. However, in practice, the substrate's neutron-nucleai optical potential does not match perfectly that for spin-down neutrons in the SM. For a positive step in the optical potential (as in a Fe/SiN(x) SM on Si substrate), this mismatch results in spin-independent total reflection for neutrons with small momentum transfer Q, limiting the useful neutron bandwidth in the low-Q region. To overcome this limitation, we propose to replace Si single-crystal substrates by media with higher optical potential than that for spin-down neutrons in the SM ferromagnetic layers. We found single-crystal sapphire and single-crystal quartz as good candidates for solid-state Fe/SiN(x) SM polarizers. To verify this idea, we coated a thick plate of single-crystal sapphire with a m=2.4 Fe/SiN(x) SM. At ...

  3. A new mechanism for generating broad band pulsar-like polarization

    Energy Technology Data Exchange (ETDEWEB)

    Singleton, John [Los Alamos National Laboratory; Fasel, Joseph [Los Alamos National Laboratory; Middleditch, John [Los Alamos National Laboratory; Perez, Mario [Los Alamos National Laboratory; Schmidt, Andrea [Los Alamos National Laboratory; Ardavan, Arzhang [OXFORD UNIV; Ardavan, Houshang [U OF CAMBRIDGE

    2009-01-01

    Observational data imply the presence of superluminal electric currents in pulsar magnetospheres. Such sources are not inconsistent with special relativity; they have already been created in the laboratory. Here we describe the distinctive features of the radiation beam that is generated by a rotating superluminal source and show that it consists of subbeams that are narrower the farther the observer is from the source: subbeams whose intensities decay as 1/R instead of 1/R{sup 2} with distance (R), the fields of its subbeams are characterized by three concurrent polarization modes: two modes that are 'orthogonal' and a third mode whose position angle swings across the subbeam bridging those of the other two, (iii) its overall beam consists of an incoherent superposition of such coherent subbeams and has an intensity profile that reflects the azimuthal distribution of the contributing part of the source (the part of the source that approaches the observer with the speed of light and zero acceleration), its spectrum (the superluminal counterpart of synchrotron spectrum) is broader than that of any other known emission and entails oscillations whose spacings and amplitudes respectively increase and decrease algebraically with increasing frequency, and the degree of its mean polarization and the fraction of its linear polarization both increase with frequency beyond the frequency for which the observer falls within the Fresnel zone. We also compare these features with those of the radiation received from the Crab pulsar.

  4. Seismo-volcano source localization with triaxial broad-band seismic array

    Science.gov (United States)

    Inza, L. A.; Mars, J. I.; Métaxian, J. P.; O'Brien, G. S.; Macedo, O.

    2011-10-01

    Seismo-volcano source localization is essential to improve our understanding of eruptive dynamics and of magmatic systems. The lack of clear seismic wave phases prohibits the use of classical location methods. Seismic antennas composed of one-component (1C) seismometers provide a good estimate of the backazimuth of the wavefield. The depth estimation, on the other hand, is difficult or impossible to determine. As in classical seismology, the use of three-component (3C) seismometers is now common in volcano studies. To determine the source location parameters (backazimuth and depth), we extend the 1C seismic antenna approach to 3Cs. This paper discusses a high-resolution location method using a 3C array survey (3C-MUSIC algorithm) with data from two seismic antennas installed on an andesitic volcano in Peru (Ubinas volcano). One of the main scientific questions related to the eruptive process of Ubinas volcano is the relationship between the magmatic explosions and long-period (LP) swarms. After introducing the 3C array theory, we evaluate the robustness of the location method on a full wavefield 3-D synthetic data set generated using a digital elevation model of Ubinas volcano and an homogeneous velocity model. Results show that the backazimuth determined using the 3C array has a smaller error than a 1C array. Only the 3C method allows the recovery of the source depths. Finally, we applied the 3C approach to two seismic events recorded in 2009. Crossing the estimated backazimuth and incidence angles, we find sources located 1000 ± 660 m and 3000 ± 730 m below the bottom of the active crater for the explosion and the LP event, respectively. Therefore, extending 1C arrays to 3C arrays in volcano monitoring allows a more accurate determination of the source epicentre and now an estimate for the depth.

  5. High sensitivity ultra-broad-band absorption spectroscopy of inductively coupled chlorine plasma

    OpenAIRE

    Marinov, Daniil; Foucher, Mickaël; Campbell, Ewen; Brouard, Mark; Chabert, Pascal; Booth, Jean-Paul

    2016-01-01

    International audience We propose a method to measure the densities of vibrationally excited Cl 2 (v) molecules in levels up to v = 3 in pure chlorine inductively coupled plasmas. The absorption continuum of Cl 2 in the 250 – 450 nm spectral range is deconvoluted into the individual components originating from the different vibrational levels of the ground state, using a set of ab-initio absorption cross sections. It is shown that gas heating at constant pressure is the major depletion mec...

  6. Study of Zweig's rule using phi mesons in a broad band neutral beam

    International Nuclear Information System (INIS)

    A study of Zweig's rule using phi mesons in a high energy photon beam was performed. Measurement of the ratio sigma(γA → phi ππA)/sigma(γA → ωππA) = 0.10 +- 0.02 is taken as evidence that there is not as strong suppression as could be expected. Other ratios show strange particle production down from nonstrange particle production by a factor of twelve. Decays involving phi mesons are studied, and the only candidate seen is a four sigma effect in the mode two phis with a mass 2.15 GeV. F meson, charm pseudo-scalar meson and exotic vector mesons which might decay into phis are not seen. The phi prime is not seen with an upper limit sigma(γA → phi'A)B(phi' → K+K-π+π-) < 6 nb per nucleon

  7. Broad band Transmission Performance over Residential Power Lines Employing VDSL2

    Directory of Open Access Journals (Sweden)

    Usha Rani K R

    2013-01-01

    Full Text Available Bridging and Transmission of VDSL2 broadband over power lines has received considerable attention recently to cater to broadband distribution within the premises of a residence. Power lines are fundamentally different from telephone lines both in topology and load impedance. Power lines have a thicker gauge and shorter straight lengths, apart from a large number of bridge taps (BT with inductive load terminations, which are not matched to line impedances. In this paper ABCD parameters of the individual sections are used to analyze the power line channel of upto 10 bridge taps over a 600 meter length. The noise profiles considered include periodic impulse noise which is predominant over power line sections, apart from AWGN. Tone loading profiles have been obtained using Discrete Multitone Transmission (DMT as in VDSL2 over a bandwidth of 30 MHz. This analysis points to the fact that lower Transmit PSD would suffice to match the rates achievable by traditional VDSL2 when bridge taps are open. However with inductive loads typical in residences, we recommend a two step approach of (a equipping existing VDSL2 modem front end hybrids with settable impedances that would approach a conjugate match of the loaded line along with (b capability to nominally increase the Transmit PSD and added subbands to achieve the desired rates in a seamless manner as in VDSL2.

  8. A compact planar multi-broad band monopole antenna for mobile devices

    Science.gov (United States)

    Zhong, Xiaoqing; Yao, Bin; Zheng, Qinhong; Yang, Jikong; Cao, Xiangqi

    2015-10-01

    A Multiple-frequency broadband planar monopole antenna is proposed in this Paper. The antenna is stimulated and numerically optimized by HFSS13.0 (High Frequency Structure Simulator). The size of it is 39mm×22mm×1.7mm. The antenna resonates at many frequencies. The parameter S11antenna matches well with its feed-line and covers many useful operation frequency bands, including 2G(DCS1800 and PCS1900), 3G(UMTS), 4G(LTE2300 and LTE2500), ISM, WLAN. It is quiet appropriate for the present ultra-thin smart phones

  9. Compact High-Resolution Broad-Band Terahertz Fabry-Perot Spectrometer Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Our objective is to develop a compact scanning Fabry-Perot spectrometer, for satellite far-infrared astronomy and Earth remote sensing, that operates at wavelengths...

  10. AlpArray - a broad(band) seismology initiative on the European Alps

    Science.gov (United States)

    Hetényi, G.

    2012-12-01

    AlpArray is a new initiative to study the greater Alpine area with a large-scale broadband seismological network. The interested parties (currently 57 institutes in 16 countries) plan to combine their existing infrastructures into an all-out transnational effort that includes data acquisition, processing, imaging and interpretation. The experiment will encompass the greater Alpine area from the Black Forest and the Bohemian Massif in the north to the Northern Apennines in the south and from the Pannonian Basin in the east to the French Massif Central in the west. We aim to cover this region with a high-quality broadband seismometer backbone by combining the ca. 220 existing permanent stations with additional 300-340 instruments from mobile pools, all of them to be deployed between August 2014 and August 2016. In this way, we plan to achieve homogeneous and high resolution coverage (ca. 40 km average station spacing). Furthermore, we also plan to deploy a few densely spaced targeted networks along swaths across - and in regions of - key parts of the Alpine chain on shorter time scales. These efforts on land will be combined with deployments of ca. 40-45 ocean bottom seismometers in the Mediterranean Sea. We also aim to implement the best practice for synchronizing mobile pool operation procedures and data handling: common data centre and data management procedure, free access to data to participants as soon as possible through EIDA. Data will be open to the public 3 years after the experiment ends. The main scientific goal of AlpArray is to investigate the structure and evolution of the lithosphere beneath the Alps. A primary target is the geometry and configuration of subducting slabs and their polarity switch beneath the arc. Numerous regional questions such as seismic hazard will be tackled. Targets will be imaged at several depths (e.g., from near-surface structure down to upper mantle anisotropy), scales (e.g., from local seismicity to mantle transition zone thickness variations), using different methodologies in the sub-regions of interest. An overview of these targets and the methodologies intended to be applied in connection with the seismological measurements will be presented. The geodynamic interpretation of the acquired data will be complemented by other Earth Science disciplines such as state-of-the-art numerical and analogue modelling, gravity and magneto-telluric measurements, as well as structural geology. In conclusion, we hope to turn the strong community interest into a truly interdisciplinary and collaborative project in the key region for seismotectonic activity and dynamics of Europe. At this poster we welcome anybody who is interested to hear more on the project, who would like share their experience with similar large-scale field experiment(s), and/or who has scientific, practical or funding advice.

  11. Beam-based model of broad-band impedance of the Diamond Light Source

    Science.gov (United States)

    Smaluk, Victor; Martin, Ian; Fielder, Richard; Bartolini, Riccardo

    2015-06-01

    In an electron storage ring, the interaction between a single-bunch beam and a vacuum chamber impedance affects the beam parameters, which can be measured rather precisely. So we can develop beam-based numerical models of longitudinal and transverse impedances. At the Diamond Light Source (DLS) to get the model parameters, a set of measured data has been used including current-dependent shift of betatron tunes and synchronous phase, chromatic damping rates, and bunch lengthening. A matlab code for multiparticle tracking has been developed. The tracking results and analytical estimations are quite consistent with the measured data. Since Diamond has the shortest natural bunch length among all light sources in standard operation, the studies of collective effects with short bunches are relevant to many facilities including next generation of light sources.

  12. Broad-Band Imaging of a Large Sample of Irregular Galaxies

    CERN Document Server

    Hunter, D A; Hunter, Deidre A.; Elmegreen, Bruce G.

    2005-01-01

    We present the results of UBV imaging of a large sample of irregular galaxies: 94 Im systems, 24 Blue Compact Dwarfs (BCDs), and 18 Sm galaxies. We also include JHK imaging of 41 of these galaxies. The sample spans a large range in galactic parameters. Ellipse fit axial ratios, inclinations, and position angles are derived, integrated photometry and azimuthally-averaged surface photometry profiles are determined, and exponential fits give the central surface brightnesses, scale lengths, and isophotal and half-power radii. These data are used to address the shapes of Im galaxies, look for clues to past interactions in large-scale peculiarities, examine the nature and consequences of bars, study color gradients and large-scale color variations, and compare the exponential disk profiles of the young and old stellar components. For example, color gradients exhibit a great variety and not all passbands are correlated. Bars are associated with higher star formation rates. Many irregulars show a double exponential r...

  13. Experimental estimations of viscoelastic properties of multilayer damped plates in broad-band frequency range

    CERN Document Server

    Ege, Kerem; Laulagnet, Bernard; Guyader, Jean-Louis

    2012-01-01

    Regarding lightweighting structures for aeronautics, automotive or construction applications, the level of performance of solutions proposed in terms of damping and isolation is fundamental. Hence multilayered plate appears as an interesting answer if damping performances are properly optimized. In this paper, a novel modal analysis method (Ege et al, JSV 325 (4-5), 2009) is used to identify viscoelastic properties (loss factors, Young's modulus) of "polyethylene thermoplastic / aluminum" bilayer plates. The thermoplastic is chosen for its high loss factors and relative low mass. The experimental method consists in a high-resolution technique (ESPRIT algorithm) which allows precise estimations of the viscoelastic properties even in frequency domains with high modal overlap (high damping or modal density). Experimental loss factors estimated from impact hammer excitations on the free-free plates highly corresponds with two theoretical estimations. In the first model (Guyader & Lesueur, JSV 58(1), 1978) the...

  14. High-performance broad-band spectroscopy for breast cancer risk assessment

    Science.gov (United States)

    Pawluczyk, Olga; Blackmore, Kristina; Dick, Samantha; Lilge, Lothar

    2005-09-01

    Medical diagnostics and screening are becoming increasingly demanding applications for spectroscopy. Although for many years the demand was satisfied with traditional spectrometers, analysis of complex biological samples has created a need for instruments capable of detecting small differences between samples. One such application is the measurement of absorbance of broad spectrum illumination by breast tissue, in order to quantify the breast tissue density. Studies have shown that breast cancer risk is closely associated with the measurement of radiographic breast density measurement. Using signal attenuation in transillumination spectroscopy in the 550-1100nm spectral range to measure breast density, has the potential to reduce the frequency of ionizing radiation, or making the test accessible to younger women; lower the cost and make the procedure more comfortable for the patient. In order to determine breast density, small spectral variances over a total attenuation of up to 8 OD have to be detected with the spectrophotometer. For this, a high performance system has been developed. The system uses Volume Phase Holographic (VPH) transmission grating, a 2D detector array for simultaneous registration of the whole spectrum with high signal to noise ratio, dedicated optical system specifically optimized for spectroscopic applications and many other improvements. The signal to noise ratio exceeding 50,000 for a single data acquisition eliminates the need for nitrogen cooled detectors and provides sufficient information to predict breast tissue density. Current studies employing transillumination breast spectroscopy (TIBS) relating to breast cancer risk assessment and monitoring are described.

  15. Broad band polarimetric follow-up of Type IIP SN 2012aw

    CERN Document Server

    Kumar, Brajesh; Eswaraiah, C; Gorosabel, J

    2014-01-01

    We present the results based on R-band polarimetric follow-up observations of the nearby (~10 Mpc) Type II-plateau SN 2012aw. Starting from ~10 days after the SN explosion, these polarimetric observations cover ~90 days (during the plateau phase) and are distributed over 9 epochs. To characterize the Milky Way interstellar polarization (ISP_MW ), we have observed 14 field stars lying in a radius of 10 degree around the SN. We have also tried to subtract the host galaxy dust polarization component assuming that the dust properties in the host galaxy are similar to that observed for Galactic dust and the general magnetic field follow the large scale structure of the spiral arms of a galaxy. After correcting the IS_PMW , our analysis infer that SN 2012aw has maximum polarization of 0.85% +- 0.08% but polarization angle does not show much variation with a weighted mean value of ~138 degree. However, if both ISP_MW and host galaxy polarization (ISP_HG ) components are subtracted from the observed polarization valu...

  16. Broad Band Optical Properties of Large Area Monolayer CVD Molybdenum Disulfide

    OpenAIRE

    Li, Wei; Birdwell, A. Glen; Amani, Matin; Burke, Robert A.; Ling, Xi; Lee, Yi-Hsien; Liang, Xuelei; Peng, Lianmao; Richter, Curt A.; Kong, Jing; Gundlach, David J.; Nguyen, N.V.

    2014-01-01

    Recently emerging large-area single-layer MoS2 grown by chemical vapor deposition has triggered great interest due to its exciting potential for applications in advanced electronic and optoelectronic devices. Unlike gapless graphene, MoS2 has an intrinsic band gap in the visible which crosses over from an indirect to a direct gap when reduced to a single atomic layer. In this article, we report a comprehensive study of fundamental optical properties of MoS2 revealed by optical spectroscopy of...

  17. Broad-band chopper for a CW proton linac at Fermilab

    Energy Technology Data Exchange (ETDEWEB)

    Gianfelice-Wendt, E.; Lebedev, V.A.; Solyak, N.; Nagaitsev, S.; Sun, D.; /Fermilab

    2011-03-01

    The future Fermilab program in the high energy physics is based on a new facility called the Project X [1] to be built in the following decade. It is based on a 3 MW CW linear accelerator delivering the 3 GeV 1 mA H{sup -} beam to a few experiments simultaneously. Small fraction of this beam will be redirected for further acceleration to 8 GeV to be injected to the Recycler/Main Injector for a usage in a neutrino program and other synchrotron based high energy experiments. Requirements and technical limitations to the bunch-by-bunch chopper for the Fermilab Project X are discussed.

  18. Broad Band Observations of Gravitationally Lensed Blazar during a Gamma-Ray Outburst

    Directory of Open Access Journals (Sweden)

    Julian Sitarek

    2016-09-01

    Full Text Available QSO B0218+357 is a gravitationally lensed blazar located at a cosmological redshift of 0.944. In July 2014 a GeV flare was observed by Fermi-LAT, triggering follow-up observations with the MAGIC telescopes at energies above 100 GeV. The MAGIC observations at the expected time of arrival of the trailing component resulted in the first detection of QSO B0218+357 in Very-High-Energy (VHE, >100 GeV gamma rays. We report here the observed multiwavelength emission during the 2014 flare.

  19. Broad-band Gaussian noise is most effective in improving motor performance and is most pleasant.

    Science.gov (United States)

    Trenado, Carlos; Mikulić, Areh; Manjarrez, Elias; Mendez-Balbuena, Ignacio; Schulte-Mönting, Jürgen; Huethe, Frank; Hepp-Reymond, Marie-Claude; Kristeva, Rumyana

    2014-01-01

    Modern attempts to improve human performance focus on stochastic resonance (SR). SR is a phenomenon in non-linear systems characterized by a response increase of the system induced by a particular level of input noise. Recently, we reported that an optimum level of 0-15 Hz Gaussian noise applied to the human index finger improved static isometric force compensation. A possible explanation was a better sensorimotor integration caused by increase in sensitivity of peripheral receptors and/or of internal SR. The present study in 10 subjects compares SR effects in the performance of the same motor task and on pleasantness, by applying three Gaussian noises chosen on the sensitivity of the fingertip receptors (0-15 Hz mostly for Merkel receptors, 250-300 Hz for Pacini corpuscles and 0-300 Hz for all). We document that only the 0-300 Hz noise induced SR effect during the transitory phase of the task. In contrast, the motor performance was improved during the stationary phase for all three noise frequency bandwidths. This improvement was stronger for 0-300 Hz and 250-300 Hz than for 0-15 Hz noise. Further, we found higher degree of pleasantness for 0-300 Hz and 250-300 Hz noise bandwidths than for 0-15 Hz. Thus, we show that the most appropriate Gaussian noise that could be used in haptic gloves is the 0-300 Hz, as it improved motor performance during both stationary and transitory phases. In addition, this noise had the highest degree of pleasantness and thus reveals that the glabrous skin can also forward pleasant sensations.

  20. The Leaky Lens: A Broad-Band Fixed-Beam Leaky-Wave Antenna

    NARCIS (Netherlands)

    Neto, A.; Bruni, S.; Gerini, G.; Sabbadini, M.

    2005-01-01

    A novel type of leaky-wave antenna is presented. Differently from previously reported leaky-wave antennas, it is characterized by a constant beam direction over a very wide range of frequencies. The radiation originates at a slot etched at the interface between air and a dense dielectric, which is s

  1. Statistical analysis concerning broad band measurements of radio frequency electromagnetic fields

    International Nuclear Information System (INIS)

    Electromagnetic fields (EMF) actually represents one of the most common and the fastest growing environmental factors influencing human life. The care of the public community for the so called electromagnetic pollution is continually increasing because of the booming use of mobile phones over the past decade in business, commerce and social life. Moreover the incumbent third generation mobile systems will increase the use of all communication technologies, including fax, e-mail and Internet accesses. This extensive use has been accompanied by public debate about possible adverse effects on human health. In particular there are concerns related to the emission of radiofrequency radiation from the cellular phones and from base stations. Due to this very fast and wide development of cellular telephony more and more data are becoming available from monitoring, measuring and predicting electromagnetic fields as requested by the laws in order to get the authorization to install antenna and apparatus size of the database is such consistent that statistics have been carried out with a high degree of confidence: in particular in this paper statistical analysis has been focussed on data collected during about 1000 check measurements of electromagnetic field values performed by a private company in 167 different located in almost all Italian regions. One of the aim set consist in to find the most critical factors for the measurements, besides the field conformation: position in space, logistic conditions, technology employed, distance from the centre of the antenna, etc. The first step of the study deals with the building of a database fulfilled with information relevant to the measurements. In a second step, by means of appropriate statistical procedures, the electromagnetic field is evaluated and then the different measurement procedures are critically reviewed

  2. Liquid deuterium neutron attenuator for broad-band photon beam facility

    International Nuclear Information System (INIS)

    The photo-production facility at Fermilab uses a two section liquid deuterium attenuator, 103 feet in length, to reduce the neutron flux and produce a pure high energy photon beam. The facility is located in the Proton East experimental hall, and includes nine 10 foot long sweeping magnets. A unique refrigeration system supplies mechanically refrigerated helium gas trace cooling to condense deuterium directly in a flask. The control system permits remote operation of the cryogenic system and also acts as an interface to the Proton Area operations computer. The computer can be used to monitor the operating parameters and for partial control of the system. The facility is presently in use as part of the Proton Area experimental program. (auth)

  3. A tunable, linac based, intense, broad-band THz source forpump-probe experiments

    Energy Technology Data Exchange (ETDEWEB)

    Schmerge, J. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Adolphsen, C. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Corbett, J. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Dolgashev, V. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Durr, H. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Fazio, M. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Fisher, A. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Frisch, J. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Gaffney, K. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Guehr, M. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Hastings, J. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Hettel, B. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Hoffmann, M. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Hogan, M. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Holtkamp, N. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Huang, X. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Huang, Z. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Kirchmann, P. [SLAC National Accelerator Lab., Menlo Park, CA (United States); LaRue, J. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Limborg, C. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Lindenberg, A. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Loos, H. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Maxwell, T. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Nilsson, A. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Raubenheimer, T. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Reis, D. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Ross, M. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Shen, Z. -X. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Stupakov, G. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Tantawi, S. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Tian, K. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Wu, Z. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Xiang, D. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Yakimenko, V. [SLAC National Accelerator Lab., Menlo Park, CA (United States)

    2015-02-02

    We propose an intense THz source with tunable frequency and bandwidth that can directly interact with the degrees of freedom that determine the properties of materials and thus provides a new tool for controlling and directing these ultrafast processes as well as aiding synthesis of new materials with new functional properties. This THz source will broadly impact our understanding of dynamical processes in matter at the atomic-scale and in real time. Established optical pumping schemes using femtosecond visible frequency laser pulses for excitation are extended into the THz frequency regime thereby enabling resonant excitation of bonds in correlated solid state materials (phonon pumping), to drive low energy electronic excitations, to trigger surface chemistry reactions, and to all-optically bias a material with ultrashort electric fields or magnetic fields. A linac-based THz source can supply stand-alone experiments with peak intensities two orders of magnitude stronger than existing laser-based sources, but when coupled with atomic-scale sensitive femtosecond x-ray probes it opens a new frontier in ultrafast science with broad applications to correlated materials, interfacial and liquid phase chemistry, and materials in extreme conditions.

  4. Data Acquisition and Control System for Broad-band Microwave Reflectometry on EAST

    CERN Document Server

    Wen, Fei; Zhang, Shoubiao; Kong, Defeng; Wang, Yuming; Han, Xiang; Qu, Hao; Gao, Xiang

    2014-01-01

    Microwave reflectometry is a non-intrusive plasma diagnostic tool which is widely applied in many fusion devices. In 2014, the microwave reflectometry on Experimental Advanced Superconducting Tokamak (EAST) had been upgraded to measure plasma density profile and fluctuation, which covered the frequency range of Q-band (32-56 GHz), V-band (47-76 GHz) and W-band (71-110 GHz). This paper presented a dedicated data acquisition and control system (DAQC) to meet the measurement requirements of high accuracy and temporal resolution. The DAQC consisted of two control modules, which integrated arbitrary waveform generation block (AWG) and trigger processing block (TP), and two data acquisition modules (DAQ) that was implemented base on the PXIe platform from National Instruments (NI). All the performance parameters had satisfied the requirements of reflectometry. The actual performance will be further examined in the experiments of EAST in 2014.

  5. Nest building and posture changes and activity budget of gilts housed in pens and crates

    DEFF Research Database (Denmark)

    Andersen, Inger Lise; Vasdal, Guro; Pedersen, Lene Juul

    2014-01-01

    The aim of the present work was to study nest building, posture changes and the overall activity budget of gilts in pens vs. crates. Twenty-three HB gilts (high piglet survival day 5) and 21 LB gilts (low piglet survival day 5) were video recorded from day 110 in pregnancy to four days after farr...

  6. Demonstration of Thermodynamics and Kinetics Using FriXion Erasable Pens

    Science.gov (United States)

    Campbell, Dean J.; Bosma, Wayne B.; Bannon, Stephen J.; Gunter, Molly M.; Hammar, Margaret K.

    2012-01-01

    FriXion erasable pens contain thermochromic inks that have colored low-temperature forms and colorless high-temperature forms. Liquid nitrogen can be used to kinetically trap the high-temperature forms of the ink at temperatures at which ordinarily the low-temperature forms are more thermodynamically stable. (Contains 2 figures.)

  7. Mass measurements of short-lived nuclides using the Isoltrap preparation Penning trap

    Energy Technology Data Exchange (ETDEWEB)

    Naimi, S., E-mail: Sarah.Naimi@csnsm.in2p3.fr [RIKEN, Atomic Physics Laboratory (Japan); Rosenbusch, M. [Ernst-Moritz-Arndt-Universitaet, Institut fuer Physik (Germany); Audi, G. [Universite de Paris Sud, CSNSM-IN2P3-CNRS (France); Blaum, K.; Boehm, Ch.; Borgmann, Ch. [Max-Planck-Institut fuer Kernphysik (Germany); Breitenfeldt, M. [Katholieke Universiteit Leuven, Instituut voor Kern- en Stralingsfysica (Belgium); George, S. [Michigan State University, NSCL (United States); Herfurth, F. [GSI Helmholtzzentrum fuer Schwerionenforschung GmbH (Germany); Herlert, A. [University of Manchester, School of Physics and Astronomy (United Kingdom); Kowalska, M. [CERN, Physics Department (Switzerland); Kreim, S. [Max-Planck-Institut fuer Kernphysik (Germany); Lunney, D. [Universite de Paris Sud, CSNSM-IN2P3-CNRS (France); Minaya-Ramirez, E. [GSI Helmholtzzentrum fuer Schwerionenforschung GmbH (Germany); Neidherr, D. [Johannes Gutenberg-Universitaet, Institut fuer Physik (Germany); Schweikhard, L. [Ernst-Moritz-Arndt-Universitaet, Institut fuer Physik (Germany); Wang, M. [Universite de Paris Sud, CSNSM-IN2P3-CNRS (France)

    2011-07-15

    For exotic nuclear species, short decay half-lives make precision mass measurements particularly challenging. Combining isobaric purification and the mass measurement in the same trap may offer an interesting compromise between losses due to half-life and measurement precision. Here we discuss a mass measurement performed in a preparation Penning trap, and perform a study of the resonance lineshape.

  8. Personality and psychopathology: a theory-based revision of Eysenck's PEN Model

    NARCIS (Netherlands)

    Kampen, van D.

    2009-01-01

    The principal aim of this paper is to investigate whether it is possible to create a personality taxonomy of clinical relevance out of Eysenck’s original PEN model by repairing the various shortcomings that can be noted in Eysenck’s personality theory, particularly in relation to P or Psychoticism.

  9. Shallow seismic structure of the Pen Duick area, Gulf of Cadiz

    Science.gov (United States)

    de Haas, Henk; van Weering, Tjeerd C. E.; Tokarev, Mikhail; Ivanov, Michael; Gorban, Anna; Mienis, Furu

    2010-05-01

    This paper addresses the relationship between structural features, seabed morphology and carbonate mounds in the Pen Duick and Renard Ridge area of the El Arraiche mud volcano field in the south-eastern Gulf of Cadiz, based on seismic and multibeam echosounder data. In 2006 a grid of 100 high resolution 24-channel seismic lines with a length of about 5 nautical miles and a spacing of about 50 m mainly aligned NE-SW and NW-SE was recorded using an array of three sleeve guns (40, 20 and 10 cu.inch) towed at 37 meters behind the ship. Shooting was done every 5 seconds at a pressure of 100 bars and an average sailing speed of 4.2 knots, thus with an average shot distance of 10.5 metres across the Pen Duick Escarpment and the Lazarillo de Tormes mud volcano. Addditional lines were recorded as cross lines for correlation accross the western cone of the Gemini mud volcano. During a follow-up cruise in October 2006 with RV Pelagia, the multibeam coverage was expanded to include the Gemini and Al Idrissi mud volcanoes and adjacent area. NMO corrections, CDP stacking and swell correction were applied to improve the raw images. Results show that the Pen Duick Escarpment is lined along its upper flank with a string of relatively small and steep mound structures. The majority of mounds concentrate on the top and on the western slope of the Pen Duick Escarpment. A large chain of mounds (about 1.6 km long) is situated to the west of the Pen Duick Escarpment. There are also small isolated groups of mounds located to the east of the Pen Duick Escarpment. These mounds do not show a clear internal structure. The seismic facies within the mounds are chaotic. The mounds at the Pen Duick Escarpment occur locally clustered but mainly as isolated structures They are at maximum about 50 m high, are located in water depths from 500 to 650 m and consist mainly of fine grained (muddy) sediments. Our seismic profiles do not reflect a relationship with the possible presence of gas, gashydrates

  10. Sow postural changes, responsiveness to piglet screams, and their impact on piglet mortality in pens and crates.

    Science.gov (United States)

    Melišová, M; Illmann, G; Chaloupková, H; Bozděchová, B

    2014-07-01

    Free farrowing pens (pens) improve the welfare of sows but may increase sow activity and negatively influence piglet production. The aim of this study was to assess the effect of pens and crates on sow postural changes, piglet trapping, sow responses to piglet screams, piglet mortality, and piglet BW gain. It was predicted that provision of greater space (in pens) would increase not only the frequency of sow postural changes and the probability of trappisng but also sow responses to the screams of piglets; thus, the outcome would be no differences in fatal piglet crushing or overall mortality between the housing systems. Sows were randomly moved to either a farrowing pen (n = 20) or farrowing crate (n = 18). Sow behavior was recorded and analyzed for 72 h from the birth of the first piglet (BFP). Sow postural changes included rolling from a ventral to lateral position and vice versa and going from standing to sitting, standing to lying, and sitting to lying. Occurrences of piglet trapping and sow responsiveness to real crushing situations were analyzed. Sow responsiveness was assessed in response to audio playbacks (PB) of piglet screams on d 3 postpartum (48 to 72 h after BFP; PB crush calls) and real piglet crushing during the first 72 h after BFP (real crush calls). Piglet BW gain was estimated 24 h after BFP, piglet BW was recorded at weaning, and piglet crushing and piglet mortality were recorded during the 72 h after BFP. Data were analyzed using PROC MIXED and PROC GENMOD of SAS. Sows in pens showed more postural changes (P = 0.04) and tended to have greater incidences of piglet trapping (P = 0.07) than those in crates. Sow response to PB crush calls was greater in pens (P = 0.04) but did not differ for real crush calls between pens and crates (P = 0.62). There was no effect on the probability of piglet crushing (P = 0.38) and mortality (P = 0.41) during the 72 h after BFP nor in piglet mortality at weaning (P = 0.81) between pens and crates. Piglet BW gain

  11. Sow postural changes, responsiveness to piglet screams, and their impact on piglet mortality in pens and crates.

    Science.gov (United States)

    Melišová, M; Illmann, G; Chaloupková, H; Bozděchová, B

    2014-07-01

    Free farrowing pens (pens) improve the welfare of sows but may increase sow activity and negatively influence piglet production. The aim of this study was to assess the effect of pens and crates on sow postural changes, piglet trapping, sow responses to piglet screams, piglet mortality, and piglet BW gain. It was predicted that provision of greater space (in pens) would increase not only the frequency of sow postural changes and the probability of trappisng but also sow responses to the screams of piglets; thus, the outcome would be no differences in fatal piglet crushing or overall mortality between the housing systems. Sows were randomly moved to either a farrowing pen (n = 20) or farrowing crate (n = 18). Sow behavior was recorded and analyzed for 72 h from the birth of the first piglet (BFP). Sow postural changes included rolling from a ventral to lateral position and vice versa and going from standing to sitting, standing to lying, and sitting to lying. Occurrences of piglet trapping and sow responsiveness to real crushing situations were analyzed. Sow responsiveness was assessed in response to audio playbacks (PB) of piglet screams on d 3 postpartum (48 to 72 h after BFP; PB crush calls) and real piglet crushing during the first 72 h after BFP (real crush calls). Piglet BW gain was estimated 24 h after BFP, piglet BW was recorded at weaning, and piglet crushing and piglet mortality were recorded during the 72 h after BFP. Data were analyzed using PROC MIXED and PROC GENMOD of SAS. Sows in pens showed more postural changes (P = 0.04) and tended to have greater incidences of piglet trapping (P = 0.07) than those in crates. Sow response to PB crush calls was greater in pens (P = 0.04) but did not differ for real crush calls between pens and crates (P = 0.62). There was no effect on the probability of piglet crushing (P = 0.38) and mortality (P = 0.41) during the 72 h after BFP nor in piglet mortality at weaning (P = 0.81) between pens and crates. Piglet BW gain

  12. Transport of three veterinary antimicrobials from feedlot pens via simulated rainfall runoff.

    Science.gov (United States)

    Sura, Srinivas; Degenhardt, Dani; Cessna, Allan J; Larney, Francis J; Olson, Andrew F; McAllister, Tim A

    2015-07-15

    Veterinary antimicrobials are introduced to wider environments by manure application to agricultural fields or through leaching or runoff from manure storage areas (feedlots, stockpiles, windrows, lagoons). Detected in manure, manure-treated soils, and surface and ground water near intensive cattle feeding operations, there is a concern that environmental contamination by these chemicals may promote the development of antimicrobial resistance in bacteria. Surface runoff and leaching appear to be major transport pathways by which veterinary antimicrobials eventually contaminate surface and ground water, respectively. A study was conducted to investigate the transport of three veterinary antimicrobials (chlortetracycline, sulfamethazine, tylosin), commonly used in beef cattle production, in simulated rainfall runoff from feedlot pens. Mean concentrations of veterinary antimicrobials were 1.4 to 3.5 times higher in surface material from bedding vs. non-bedding pen areas. Runoff rates and volumetric runoff coefficients were similar across all treatments but both were significantly higher from non-bedding (0.53Lmin(-1); 0.27) than bedding areas (0.40Lmin(-1); 0.19). In keeping with concentrations in pen surface material, mean concentrations of veterinary antimicrobials were 1.4 to 2.5 times higher in runoff generated from bedding vs. non-bedding pen areas. Water solubility and sorption coefficient of antimicrobials played a role in their transport in runoff. Estimated amounts of chlortetracycline, sulfamethazine, and tylosin that could potentially be transported to the feedlot catch basin during a one in 100-year precipitation event were 1.3 to 3.6ghead(-1), 1.9ghead(-1), and 0.2ghead(-1), respectively. This study demonstrates the magnitude of veterinary antimicrobial transport in feedlot pen runoff and supports the necessity of catch basins for runoff containment within feedlots.

  13. Analysis of archaeological triacylglycerols by high resolution nanoESI, FT-ICR MS and IRMPD MS/MS: Application to 5th century BC-4th century AD oil lamps from Olbia (Ukraine)

    Science.gov (United States)

    Garnier, Nicolas; Rolando, Christian; Høtje, Jakob Munk; Tokarski, Caroline

    2009-07-01

    This work presents the precise identification of triacylglycerols (TAGs) extracted from archaeological samples using a methodology based on nanoelectrospray and Fourier transform mass spectrometry. The archaeological TAG identification needs adapted sample preparation protocols to trace samples in advanced degradation state. More precisely, the proposed preparation procedure includes extraction of the lipid components from finely grinded ceramic using dichloromethane/methanol mixture with additional ultrasonication treatment, and TAG purification by solid phase extraction on a diol cartridge. Focusing on the analytical approach, the implementation of "in-house" species-dependent TAG database was investigated using MS and InfraRed Multiphoton Dissociation (IRMPD) MS/MS spectra; several vegetal oils, dairy products and animal fats were studied. The high mass accuracy of the Fourier transform analyzer ([Delta]m below 2.5 ppm) provides easier data interpretation, and allows distinction between products of different origins. In details, the IRMPD spectra of the lithiated TAGs reveal fragmentation reactions including loss of free neutral fatty acid and loss of fatty acid as [alpha],[beta]-unsaturated moieties. Based on the developed preparation procedure and on the constituted database, TAG extracts from 5th century BC to 4th century AD Olbia lamps were analyzed. The structural information obtained succeeds in identifying that bovine/ovine fats were used as fuel used in these archaeological Olbia lamps.

  14. Charge transfer and penning ionization of dopants in or on helium nanodroplets exposed to EUV radiation.

    Science.gov (United States)

    Buchta, Dominic; Krishnan, Siva R; Brauer, Nils B; Drabbels, Marcel; O'Keeffe, Patrick; Devetta, Michele; Di Fraia, Michele; Callegari, Carlo; Richter, Robert; Coreno, Marcello; Prince, Kevin C; Stienkemeier, Frank; Moshammer, Robert; Mudrich, Marcel

    2013-05-30

    Helium nanodroplets are widely used as a cold, weakly interacting matrix for spectroscopy of embedded species. In this work, we excite or ionize doped He droplets using synchrotron radiation and study the effect onto the dopant atoms depending on their location inside the droplets (rare gases) or outside at the droplet surface (alkali metals). Using photoelectron-photoion coincidence imaging spectroscopy at variable photon energies (20-25 eV), we compare the rates of charge-transfer to Penning ionization of the dopants in the two cases. The surprising finding is that alkali metals, in contrast to the rare gases, are efficiently Penning ionized upon excitation of the (n = 2)-bands of the host droplets. This indicates rapid migration of the excitation to the droplet surface, followed by relaxation, and eventually energy transfer to the alkali dopants.

  15. Penning traps with unitary architecture for storage of highly charged ions

    CERN Document Server

    Tan, Joseph N; Guise, Nicholas D; 10.1063/1.3685246

    2012-01-01

    Penning traps are made extremely compact by embedding rare-earth permanent magnets in the electrode structure. Axially-oriented NdFeB magnets are used in unitary architectures that couple the electric and magnetic components into an integrated structure. We have constructed a two- magnet Penning trap with radial access to enable the use of laser or atomic beams, as well as the collection of light. An experimental apparatus equipped with ion optics is installed at the NIST electron beam ion trap (EBIT) facility, constrained to fit within 1 meter at the end of a horizontal beamline for transporting highly charged ions. Highly charged ions of neon and argon, extracted with initial energies up to 4000 eV per unit charge, are captured and stored to study the confinement properties of a one-magnet trap and a two-magnet trap. Design considerations and some test results are discussed.

  16. Status and Outlook of CHIP-TRAP: the Central Michigan University High Precision Penning Trap

    CERN Document Server

    Redshaw, Matthew; Hawks, Paul; Gamage, Nadeesha D; Hunt, Curtis; Kandegedara, Rathnayake M E B; Ratnayake, Ishara S; Sharp, Lance

    2015-01-01

    At Central Michigan University we are developing a high-precision Penning trap mass spectrometer (CHIP-TRAP)that will focus on measurements with long-lived radioactive isotopes. CHIP-TRAP will consist of a pair of hyperbolic precision-measurement Penning traps, and a cylindrical capture/?filter trap in a 12 T magnetic field. Ions will be produced by external ion sources, including a laser ablation source, and transported to the capture trap at low energies enabling ions of a given m=q ratio to be selected via their time-of-flight. In the capture trap, contaminant ions will be removed with a mass-selective rf dipole excitation and the ion of interest will be transported to the measurement traps. A phase-sensitive image charge detection technique will be used for simultaneous cyclotron frequency measurements on single ions in the two precision traps, resulting in a reduction in statistical uncertainty due to magnetic field fluctuations.

  17. Fabrication and performance of PEN SOFCs with proton-conducting electrolyte

    Institute of Scientific and Technical Information of China (English)

    ZHONG Li; LUO Jingli

    2007-01-01

    A positive-electrolyte-negative (PEN) assembly solid oxide fuel cell (SOFC) with a thin electrolyte film for intermediate temperature operation was fabricated.Instead of the traditional screen-printing method,both anode and cathode catalysts were pressed simultaneously and formed with the fabrication of nano-composite electrolyte by press method.This design offered some advantageous configurations that diminished ohmic resistance between electrolyte and electrodes.It also increased the proton-conducting rate and improved the performance of SOFCs due to the reduction of membrane thickness and good contact between electrolyte and electrodes.The fabricated PEN cell generated electricity between 600℃ and 680~C using H2S as fuel feed and Ni-S-based composite anode,nano-composite electrolyte (Li2SO4 + Al2O3) film and a NiO-based composite cathode were achieved at 600℃ and 680℃,respectively.

  18. Transparent conducting ZnO:Ga films prepared on PEN substrates by using RF magnetron sputtering

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Jeong-Yeon; Kim, Byeong-Guk; Lee, Seok-Jin; Park, Seung-Beum; Park, Jae-Hwan; Lim, Dong-Gun; Kweon, Soon-Yong [Chungju National University, Chungju (Korea, Republic of)

    2010-05-15

    The use of transparent conducting oxide films on polymer substrates has increased, as these substrates are suitable for flexible displays and optoelectronics. In this research, we studied the effects of O{sub 2} plasma pretreatment on the properties of Ga-doped zinc- oxide (GZO) films on PEN substrates. The films were fabricated using the RF magnetron sputtering process. To improve the surface adhesion and the electrical properties, the O{sub 2} plasma pretreatment process prior to GZO sputtering. With the appropriate O{sub 2} plasma treatment, the resistivity of the GZO films on the PEN substrates was 1.5 x 10{sup -3} ohm-cm. The transmittance of the films on the substrates at a wavelength of 550 nm was about 90%.

  19. High-precision masses of neutron-deficient rubidium isotopes using a Penning trap mass spectrometer

    CERN Document Server

    Kellerbauer, A G; Beck, D; Blaum, K; Bollen, G; Guénaut, C; Herfurth, F; Herlert, A; Kluge, H J; Lunney, D; Schwarz, S; Schweikhard, L; Weber, C; Yazidjian, C

    2007-01-01

    The atomic masses of the neutron-deficient radioactive rubidium isotopes $^{74-77,79,80,83}$Rb have been measured with the Penning trap mass spectrometer ISOLTRAP. Using the time-of-flight cyclotron resonance technique, relative mass uncertainties ranging from $1.6 \\times 10^{-8}$ to $5.6 \\times 10^{-8}$ were achieved. In all cases, the mass precision was significantly improved as compared with the prior Atomic-Mass Evaluation; no significant deviations from the literature values were observed. The exotic nuclide $^{74}$Rb with a half-life of only 65 ms, is the shortest-lived nuclide on which a high-precision mass measurement in a Penning trap has been carried out. The significance of these measurements for a check of the conserved-vector-current hypothesis of the weak interaction and the unitarity of the Cabibbo-Kobayashi-Maskawa matrix is discussed.

  20. Fabrication of High Aspect Ratio Micro-Penning-Malmberg Gold Plated Silicon Trap Arrays

    CERN Document Server

    Narimannezhad, Alireza; Weber, Marc H; Lynn, Kelvin G

    2013-01-01

    Acquiring a portable high density charged particles trap might consist of an array of micro-Penning-Malmberg traps (microtraps) with substantially lower end barriers potential than conventional Penning-Malmberg traps [1]. We report on the progress of the fabrication of these microtraps designed for antimatter storage such as positrons. The fabrication of large length to radius aspect ratio (1000:1) microtrap arrays involved advanced techniques including photolithography, deep reactive ion etching (DRIE) of silicon wafers to achieve through-vias, gold sputtering of the wafers on the surfaces and inside the vias, and thermal compression bonding of the wafers. This paper describes the encountered issues during fabrication and addresses geometry errors and asymmetries. In order to minimize the patch effects on the lifetime of the trapped positrons, the bonded stacks were gold electroplated to achieve a uniform gold surface. We show by simulation and analytical calculation that how positrons confinement time depen...

  1. Reliability of short form-36 in an Internet- and a pen-and-paper version

    DEFF Research Database (Denmark)

    Basnov, Maja; Kongsved, Sissel Marie; Bech, Per;

    2009-01-01

    Use of Internet versions of questionnaires may have several advantages in clinical and epidemiological research, but we know little about if Internet versions differ with respect to validity and reliability. We aimed to compare Internet- and pen-and-paper versions of short form-36 (SF-36) with re......Use of Internet versions of questionnaires may have several advantages in clinical and epidemiological research, but we know little about if Internet versions differ with respect to validity and reliability. We aimed to compare Internet- and pen-and-paper versions of short form-36 (SF-36...... in the alternative version. Test-retest reliability was assessed by the intra-class correlation coefficient. Internal consistency was calculated as Cronbach's alpha. The between-version test-retest reliability for the eight subscales were between 0.63 and 0.92. Cronbach's alpha for the two versions were all between...

  2. The effects of pen partitions and thermal pig simulators on airflow in a livestock test room

    DEFF Research Database (Denmark)

    Bjerg, B.; Svidt, Kjeld; Zhang, G.;

    2000-01-01

    measurements and CFD simulations showed that the introduction of pen partitions and thermal pig simulators reduced the air velocities in the occupied zone of the test room. Detailed geometric modelling of the animals might often be unnecessary for simulation of airflow in livestock rooms. This will especially......The aim of this work was to investigate the influence of pen partitions and heated simulated pigs on airflow in a slot ventilated test room and to evaluate computer fluid dynamics (CFD) as a tool to predict airflow in livestock rooms. To obtain two-dimensional flow in the occupied zone, four...... guiding plates were mounted beneath the ceiling in the test room. Experiments were carried out in three arrangements: (a) the room with guiding plates; (b) the room with guiding plates and eight heated pig simulators; and (c) the room with guiding plates, eight heated pig simulators and 0.8 m high...

  3. 头孢曲松低敏淋球菌中penA基因的初步研究%A Preliminary Study on the PenA Gene in Neisseria Gonorrhoeae Isolates with Reduced Susceptibility to Ceftriaxone

    Institute of Scientific and Technical Information of China (English)

    其木格; 张秀丽; 塔娜; 董磊

    2013-01-01

    目的:检测头孢曲松低敏淋球菌中penA基因的改变,探讨其是否与淋球菌对头孢曲松敏感性降低有关.方法:通过对5株头孢曲松低敏和1株头孢曲松敏感的淋球菌进行penA基因全基因测序,进一步了解penA基因的碱基置换或插入情况及青霉素结合蛋白2(PBP2)的结构模式.结果:5株头孢曲松低敏淋球菌的penA基因中有多个碱基置换或突变,没有发现含有镶嵌状penA基因结构模式.结论:penA基因的多个碱基置换或突变可能与淋球菌对头孢曲松敏感性降低相关.

  4. DD-08PHASE I CANCER CLINICAL TRIAL FOR 4-DEMETHYL-4-CHOLESTERYLOXYCARBONYLPENCLOMEDINE (DM-CHOC-PEN)

    Science.gov (United States)

    Ware, Marcus; Weiner, Roy; Friedlander, Paul; Gordon, Crag; Saenger, Yvonne; Mahmood, Tallat; Rodgers, Andrew; Bastian, Gerald; Urien, S.; Lee; Morgan, Roy

    2014-01-01

    PURPOSE: DM-CHOC-PEN is a poly-chlorinated pyridine cholesteryl carbonate whose MOA is via alkylation of DNA @ N7 – guanine and via oxidative stress. The aims of this clinical trial were to determine maximum-tolerated dose (MTD), safety, dose-limiting toxicities (DLTs), pharmacokinetics (PK) of DM-CHOC-PEN and monitor for clinical responses. METHODS: DM-CHOC-PEN was administered as a 3-hr IV infusion once every 21-days to patients with advanced cancer; melanoma (n = 3), colorectal CA (n = 3), breast (n = 3) and glioblastoma multiforme (n = 6). The trial included patients with advanced cancer +/- CNS involvement. The starting dose was 39 mg/m2 with escalations to date up to 111 mg/m2. RESULTS: Twenty-six (26) patients have been treated. The MTD was 2-tiered and defined as 85.8 mg/m2 for patients with liver involvement and 98.7 mg/m2 for patients without liver abnormalities. The most common adverse effects were fatigue (n = 2), liver dysfunction – elevated bilirubin (Gr-3, n = 3; Gr-2, n = 1), ALT/AST (Gr-2, n = 3), alk phos (Gr-2, n = 3) and an allergic reaction (Gr-2, n = 1). Three (3) patients with liver metastasis demonstrated hyperbilirubinemia (Gr-3 SLT) – 2 at the 98.7 mg/m2 and one (1) at the 111 mg/m2 levels Five (5) additional patients with liver disease have been treated at 85.8 mg/m2 level without toxicity. CONCLUSIONS: DM-CHOC-PEN is safe at the presented dose levels and has a favorable PK profile. Eight (8) patients had responses or significant PFS, including 6 with CNS involvement. A Phase II trial has begun in patients with primary brain cancer and brain metastases from melanoma, breast cancer and lung cancer.

  5. pOM: Linking Pen Gestures to Computer-Aided Composition Processes

    OpenAIRE

    Garcia, Jérémie; Leroux, Philippe; Bresson, Jean

    2014-01-01

    International audience Illuminated manuscripts of medieval music contain rich decorations in addition to handwritten neumatic notation. Our project with composer Philippe Leroux investigates the use of such handwritten symbols during the composition of his piece Quid sit musicus. We introduce pOM, an interactive paper application and a library for the OpenMusic computer-aided composition environment which links pen gestures over an old manuscript to compositional processes. The paper inter...

  6. The mechanical design and simulation of a scaled H{sup −} Penning ion source

    Energy Technology Data Exchange (ETDEWEB)

    Rutter, T., E-mail: theo.rutter@stfc.ac.uk; Faircloth, D.; Turner, D.; Lawrie, S. [Rutherford Appleton Laboratory, Didcot OX110QX (United Kingdom)

    2016-02-15

    The existing ISIS Penning H{sup −} source is unable to produce the beam parameters required for the front end test stand and so a new, high duty factor, high brightness scaled source is being developed. This paper details first the development of an electrically biased aperture plate for the existing ISIS source and second, the design, simulation, and development of a prototype scaled source.

  7. Optical pen-size reflectometer for monitoring of early dental erosion in native and polished enamels

    OpenAIRE

    Rakhmatullina, Ekaterina; Bossen, Anke; Bachofner, Kai K.; Meier, Christoph; Lussi, Adrian

    2013-01-01

    Application of the specular reflection intensity was previously reported for the quantification of early dental erosion. Further development of the technique and assembly of the miniaturized pen-size instrument are described. The optical system was adjusted to fit into a handy device which could potentially access different positions in the oral cavity. The assembled instrument could successfully detect early erosion progression in both polished (n=70) and native (n=20) human enamels. Differe...

  8. Managing infertility with the follitropin alfa prefilled pen injector - patient considerations.

    Science.gov (United States)

    Bühler, Klaus

    2015-01-01

    Gonadotropin treatment has been used in fertility treatment since the 1930s. First, preparations coming from animals were injected, then, gonadotropins prepared from the pituitary glands of human cadavers. A great step was achieved with the introduction of human menopausal gonadotropin extracted from the urine of postmenopausal women. When cases of Creutzfeld-Jacob disease were recognized after the use of human pituitary-derived hormone injections, urinary gonadotropins were increasingly purified and then produced by the use of recombinant DNA technology. Recombinant gonadotropins were characterized by the extreme high specificity and the nearly 100% purity. This allows for follitropin alfa, the first recombinant-human follicle stimulating hormone (r-hFSH) approved, to be quantified and filled by mass, with a small variance of only ±2% and no more with a bioassay with a variance of 45%. With recombinant preparations, it is also possible to cover the tremendous growing demand for gonadotropins. Ovarian stimulation has become a self-injecting procedure for the patients. Accurate and easy-to-use injection devices which minimize pain, difficulty, and stress are essential for patient compliance. So, two pen injectors adapted from the well-known insulin pen were introduced in fertility treatment, one as a multiple-use device rechargeable with premixed, prefilled cartridges with r-hFSH (follitropin β) and the other a disposable, prefilled drug delivery system with a liquid formulation of follitropin alfa filled by mass. The efficacy in comparison to the quite more cumbersome handling with ampoules and syringes has been proven very quickly. In several studies, it has been shown that patients had a preference to the prefilled follitropin alfa pen due to the faster preparation and were more confident of accurate dosing. The follitropin alfa (filled by mass [FbM]) prefilled pen is a move toward better quality of treatment and also better quality of life for the women within

  9. Application of the CO2-PENS risk analysis tool to the Rock Springs Uplift, Wyoming

    Science.gov (United States)

    Stauffer, P.H.; Pawar, R.J.; Surdam, R.C.; Jiao, Z.; Deng, H.; Lettelier, B.C.; Viswanathan, H.S.; Sanzo, D.L.; Keating, G.N.

    2011-01-01

    We describe preliminary application of the CO2-PENS performance and risk analysis tool to a planned geologic CO2 sequestration demonstration project in the Rock Springs Uplift (RSU), located in south western Wyoming. We use data from the RSU to populate CO2-PENS, an evolving system-level modeling tool developed at Los Alamos National Laboratory. This tool has been designed to generate performance and risk assessment calculations for the geologic sequestration of carbon dioxide. Our approach follows Systems Analysis logic and includes estimates of uncertainty in model parameters and Monte-Carlo simulations that lead to probabilistic results. Probabilistic results provide decision makers with a range in the likelihood of different outcomes. Herein we present results from a newly implemented approach in CO 2-PENS that captures site-specific spatially coherent details such as topography on the reservoir/cap-rock interface, changes in saturation and pressure during injection, and dip on overlying aquifers that may be impacted by leakage upward through wellbores and faults. We present simulations of CO 2 injection under different uncertainty distributions for hypothetical leaking wells and faults. Although results are preliminary and to be used only for demonstration of the approach, future results of the risk analysis will form the basis for a discussion on methods to reduce uncertainty in the risk calculations. Additionally, we present ideas on using the model to help locate monitoring equipment to detect potential leaks. By maintaining site-specific details in the CO2-PENS analysis we provide a tool that allows more logical presentations to stakeholders in the region. ?? 2011 Published by Elsevier Ltd.

  10. Experimental transmission by mosquitoes of Plasmodium hermani between domestic turkeys and pen-reared bobwhites.

    Science.gov (United States)

    Nayar, J K; Young, M D; Forrester, D J

    1982-10-01

    Plasmodium hermani was experimentally transmitted from domestic turkey poults (Meleagris gallopavo) to pen-reared bobwhites (Colinus virginianus) and then from these bobwhites back to domestic turkey poults. Transmission was achieved by Culex nigripalpus both by bites of the mosquito and by intraperitoneal injection of sporozoites. All of the 23 bobwhites and the 13 turkeys exposed to sporozoites became infected. These results indicate that the bobwhite might be a reservoir host for this malaria of wild turkeys in nature.

  11. Experimentally transmitted marble spleen disease in pen-raised wild turkeys.

    Science.gov (United States)

    Iltis, J P; Jakowski, R M; Wyand, D S

    1975-10-01

    Pen-raised North American wild turkeys (Meleagris gallopavo L.) were experimentally infected with marble spleen disease (MSD) to determine their susceptibility to this disease. Gross and microscopic lesions were consistent with experimental MSD in pheasants and domestic turkeys: an enlarged mottled spleen, intranuclear inclusion bodies, and absence of pulmonary edema and hemorrhage. Detectable levels of viral antigen were not demonstrable in sera of turkeys using the agar gell precipitin test.

  12. Pen injected apomorphine against off phenomena in late Parkinson's disease: a double blind, placebo controlled study.

    OpenAIRE

    Ostergaard, L; Werdelin, L.; Odin, P; Lindvall, O; Dupont, E.; Christensen, P. B.; Boisen, E; Jensen, N B; Ingwersen, S H; Schmiegelow, M

    1995-01-01

    The effect, therapeutic dose range, and pharmacokinetics of apomorphine, given as subcutaneous injections by a single use pen, were evaluated in the treatment of off phenomena in 22 patients with idiopathic Parkinson's disease. At study entry a placebo controlled apomorphine test was performed, and apomorphine doses were then individually titrated (mean 3.4 (range 0.8-6.0) mg) and compared with placebo in a double blind cross over phase. With apomorphine compared with placebo the mean daily d...

  13. Integrated research on the Pen Duick cold-water coral mounds: the MiCROSYSTEMS approach

    OpenAIRE

    Van Rooij, D.; De Mol, L.; D. Blamart; Mienis, F.; L. M. Wehrmann; Barbieri, R; Maignien, L.; Templer, S. P.; Haas, H; Henriet, J.-P.; The MiCROSYSTEMS Science Team

    2010-01-01

    The ESF EuroDIVERSITY MiCROSYSTEMS project aimed to turn the cold-water coral (CWC) mounds on the Pen Duick Escarpment (PDE) in the Gulf of Cadiz into a natural laboratory, exploring this highly complex biotope and to characterize its biodiversity. A common point of discussion with all other CWC mound provinces, surpassing its broad range of regional and morphological variability, concerns the driving forces regarding the initiation of these complex deep-water systems. Both oceanographic and ...

  14. Using digital pens and digital notebooks for supporting research and teaching at university

    OpenAIRE

    Pikl, Bojan

    2014-01-01

    Digital pens combine affordances of paper and digital world. Documents with similar content could be combined into a single document called digital notebook. Our idea was to include the functionality of integrating different types of documents into a text editor, which enables users to edit the main document in one place. The application was developed for Livescribe and LaTeX because both tools are currently implemented among university teachers. Tagging helps to organize and search for do...

  15. Helping Teachers Create a Dynamic Learning Environment Using Pen-Based Technology

    OpenAIRE

    Benlloch-Dualde, José Vicente; Buendía García, Félix; Cano, Juan Carlos; Blanc Clavero, Sara; Lemus Zúñiga, Lenin Guillermo

    2013-01-01

    There is evidence that Pen-based Technologies (PBTs) can facilitate radical changes that would make it possible to address problems typically associated with lecture-based pedagogical models. In the context of universitylevel Computer Science studies, there is widespread consensus that PBTs—and tablet PCs, in particular—are tools that have great potential for encouraging interaction in the classroom and promoting a far more dynamic learning environment. In view off the complexity ...

  16. Robot Guided ‘Pen Skill’ Training in Children with Motor Difficulties

    OpenAIRE

    Katy A Shire; Hill, Liam J. B.; Snapp-Childs, Winona; Bingham, Geoffrey P.; Georgios K Kountouriotis; Barber, Sally; Mon-Williams, Mark

    2016-01-01

    Motor deficits are linked to a range of negative physical, social and academic consequences. Haptic robotic interventions, based on the principles of sensorimotor learning, have been shown previously to help children with motor problems learn new movements. We therefore examined whether the training benefits of a robotic system would generalise to a standardised test of ‘pen-skills’, assessed using objective kinematic measures [via the Clinical Kinematic Assessment Tool, CKAT]. A counterbalan...

  17. Setup of a Penning trap for precision laser spectroscopy at HITRAP

    OpenAIRE

    Andelkovic, Zoran

    2012-01-01

    Ion traps have been established as a powerful tool for ion cooling and laser spectroscopy experiments since a long time ago. SpecTrap, one of the precision experiments associated to the HITRAP facility at GSI, is implementing a Penning trap for studies of large bunches of externally produced highly charged ions. The extremely strong electric and magnetic fields that exist around the nuclei of heavy elements drastically change their electronic properties, such as energy level sp...

  18. LEBIT II: Upgrades and developments for high precision Penning trap mass measurements with rare isotopes

    Energy Technology Data Exchange (ETDEWEB)

    Redshaw, M., E-mail: redsh1m@cmich.edu [Department of Physics, Central Michigan University, Mount Pleasant, MI 48859 (United States); Bollen, G.; Bustabad, S.; Kwiatkowski, A.A.; Lincoln, D.L.; Novario, S.J. [National Superconducting Cyclotron Laboratory, East Lansing, MI 48224 (United States); Department of Physics, Michigan State University, East Lansing, MI 48224 (United States); Ringle, R.; Schwarz, S. [National Superconducting Cyclotron Laboratory, East Lansing, MI 48224 (United States); Valverde, A.A. [National Superconducting Cyclotron Laboratory, East Lansing, MI 48224 (United States); Department of Physics, Michigan State University, East Lansing, MI 48224 (United States)

    2013-12-15

    Highlights: • Development and implementation of new experimental techniques at the Low Energy Beam and Ion Trap (LEBIT) facility at the National Superconducting Cyclotron Laboratory (NSCL). • Development of a laser ablation ion source for the production of carbon clusters for use as mass references and stable isotopes for offline mass measurement programs. • Implementation of stored waveform inverse Fourier transform (SWIFT) for efficient removal of contaminant ions. • Development of a miniature Penning trap to be installed in the LEBIT magnet and used as a magnetometer for monitoring temporal variations in the magnetic field strength. • Development of a new 7 T single-ion Penning trap (SIPT) at the NSCL that will use image charge detection for ultra-high sensitivity measurements of short-lived rare isotopes with very low production rates. -- Abstract: During the next several years and decades the extension of high-precision Penning trap mass spectrometry measurements to more-exotic isotopes, lying far from the valley of stability will continue to provide significant contributions to nuclear physics. However, such measurements must overcome the challenges of working with isotopes that have low production rates and short lifetimes. At the Low Energy Beam and Ion Trap (LEBIT) facility at the National Superconducting Cyclotron Laboratory, a number of developments have been implemented or are underway to meet these challenges by minimizing rare-isotope preparation and measurement time, maximizing use of available beam time, and increasing sensitivity. These developments and the current status of the LEBIT facility will be discussed.

  19. Technical developments for an upgrade of the LEBIT Penning trap mass spectrometry facility for rare isotopes

    Energy Technology Data Exchange (ETDEWEB)

    Redshaw, M., E-mail: redshaw@nscl.msu.edu [Michigan State University, NSCL (United States); Barquest, B. R.; Bollen, G.; Bustabad, S. E. [Michigan State University, NSCL and Department of Physics and Astronomy (United States); Campbell, C. M. [LBNL (United States); Ferrer, R. [University of Leuven, Department of Physics and Astronomy (Belgium); Gehring, A. [Michigan State University, NSCL and Department of Chemistry (United States); Kwiatkowski, A. A. [Michigan State University, NSCL and Department of Physics and Astronomy (United States); Lincoln, D. L. [Michigan State University, NSCL (United States); Morrissey, D. J.; Pang, G. K. [Michigan State University, NSCL and Department of Chemistry (United States); Ringle, R.; Schwarz, S. [Michigan State University, NSCL (United States)

    2011-07-15

    The LEBIT (Low Energy Beam and Ion Trap) facility is the only Penning trap mass spectrometry (PTMS) facility to utilize rare isotopes produced via fast-beam fragmentation. This technique allows access to practically all elements lighter than uranium, and in particular enables the production of isotopes that are not available or that are difficult to obtain at isotope separation on-line facilities. The preparation of the high-energy rare-isotope beam produced by projectile fragmentation for low-energy PTMS experiments is achieved by gas stopping to slow down and thermalize the fast-beam ions, along with an rf quadrupole cooler and buncher and rf quadrupole ion guides to deliver the beam to the Penning trap. During its first phase of operation LEBIT has been very successful, and new developments are now underway to access rare isotopes even farther from stability, which requires dealing with extremely short lifetimes and low production rates. These developments aim at increasing delivery efficiency, minimizing delivery and measurement time, and maximizing use of available beam time. They include an upgrade to the gas-stopping station, active magnetic field monitoring and stabilization by employing a miniature Penning trap as a magnetometer, the use of stored waveform inverse Fourier transform (SWIFT) to most effectively remove unwanted ions, and charge breeding.

  20. A proposed method to measure relativistic kinetic energy of electrons in Penning Trap

    International Nuclear Information System (INIS)

    Penning ion trap is a versatile tool which serves as a storage device for sub-atomic particles using a combination of quadrupolar electric potential for axial confinement and a strong magnetic field for radial confinement. Trapped particles have three oscillatory motions: 1) axial motion, along the direction of the magnetic field with frequency ωz, 2) the trap modified cyclotron motion at a higher frequency ω+, 3) slow magnetron motion with frequency ω+ , where ω- z + . The cryogenic Penning trap has so far been used for various precision measurements like the measurement of (g-2) parameter of electron and positron and several other similar studies. In this work, a new method of measuring the shape of a beta spectrum by high precision measurement of the relativistic kinetic energy of the electrons using a cryogenic Penning trap is proposed. Using this method, it might be possible to measure the shape of the end-point of a beta spectrum with a high precision enabling the mass measurement of electron-neutrino

  1. Characterization of pen-tip coordinates and velocity using electromyographic signals of the forearm muscles

    Directory of Open Access Journals (Sweden)

    Inès CHIHI

    2013-05-01

    Full Text Available Handwriting is considered as one of the most delicate and complex human activities. This habit requires a certain level of evolution of the language, the control of the graphic space and a certain degree of affective and praxis development. The production of a meaningful and readable writing involves a variety of motor commands generated by the brain and sent to the muscles to define, with an extreme precision, the motion of each joint at a given time. In this paper, two models characterizing the handwriting process are proposed. Using the activities of the forearm muscles, called the ElectroMyoGraphic signals (EMG, the first model is based on the coordinates of the pen-tip moving on (x,y plan and the second model is defined from the velocity of the pen-tip. The parameters' estimation of both models is determined from the Recursive Least Square algorithm (RLS. The comparison of responses of two proposed structures shows the interest of the velocity to model the complex biological process. Indeed, the model based on the velocity shows best results then the model bases on the coordinates of the pen-tip.

  2. Marker and pen graffiti cleaning on diverse calcareous stones by different laser techniques

    Science.gov (United States)

    Andriani, S. E.; Catalano, I. M.; Daurelio, G.; Albanese, A.

    2007-05-01

    Industries nowadays continuously produce new types of inks for markers and pens, so new different graffiti appear . In this paper laser cleaning tests on 41 new marker and pen types ( fluorescent, permanent, water-based, acrylic tempera, metallic paint, waterproof inks ), applied into laboratory on different litho- type samples (Chianca, Travertino di Roma, Tufo Carparo fine grain, Sabbie), typical stones employed in much more monuments in Puglia and Italian architectures were carried out. The same ones, were exposed for twelve months to outdoor ageing, subject to sunshine, rain, wind, IR and UV solar radiations. Ablation experiments and tests by using different cleaning techniques, each one in Dry and Wet condition (classic technique, Daurelio technique 1 and Daurelio technique 2 and others new techniques) and two different Nd:YAG laser systems (Palladio by QUANTA SYSTEM and SMART CLEAN II by EL.EN.), were adopted. The experimental modes, N-Mode (1064nm - 150, 300 and 500 μs pulse duration), Q-Switch (1064nm - 8 ns pulse duration) and SFR (Short Free Running - 1064 nm - 40 to 110μs pulse duration) were tested on each marked stones. It was found that according to the different ink types and stone substrate, Q-Switch laser cleaning ablation with optimized laser technique are the best solution to marker an pen graffiti removal. The work is still in progress.

  3. Chitinolytic Bacteria-Assisted Conversion of Squid Pen and Its Effect on Dyes and Pigments Adsorption

    Directory of Open Access Journals (Sweden)

    Tzu-Wen Liang

    2015-07-01

    Full Text Available The aim of this work was to produce chitosanase by fermenting from squid pen, and recover the fermented squid pen for dye removal by adsorption. One chitosanase induced from squid pen powder (SPP-containing medium by Bacillus cereus TKU034 was purified in high purification fold (441 and high yield of activity recovery (51% by ammonium sulfate precipitation and combined column chromatography. The SDS-PAGE results showed its molecular mass to be around 43 kDa. The TKU034 chitosanase used for the chitooligomers preparation was studied. The enzyme products revealed that the chitosanase could degrade chitosan with various degrees of polymerization, ranging from 3 to 9, as well as the chitosanase in an endolytic manner. Besides, the fermented SPP was recovered and displayed a better adsorption rate (up to 99.5% for the disperse dyes (red, yellow, blue, and black than the water-soluble food colorants, Allura Red AC (R40 and Tartrazine (Y4. The adsorbed R40 on the unfermented SPP and the fermented SPP was eluted by distilled water and 1 M NaOH to confirm the dye adsorption mechanism. The fermented SPP had a slightly higher adsorption capacity than the unfermented, and elution of the dye from the fermented SPP was easier than from the unfermented. The main dye adsorption mechanism of fermented SPP was physical adsorption, while the adsorption mechanism of unfermented SPP was chemical adsorption.

  4. Preferences of lame cows for type of surface and level of social contact in hospital pens

    DEFF Research Database (Denmark)

    Jensen, M. B.; Herskin, Mette S.; Thomsen, Peter T.;

    2015-01-01

    To investigate preferences of lame cows for flooring and level of social contact, 37 lame, lactating dairy cows (diagnosed with sole ulcer or white line disease) were housed individually for 6 d in experimental hospital pens, where they could choose between 2 equally sized areas (6m × 4.5m......) with either deep-bedded sand or a rubber surface. On both surfaces, cows could choose between 2 equally sized areas either near or away from heifers in a neighboring group pen. Cows spent more time lying on the deep-bedded sand than on the rubber surface (870 vs. 71min/d), whereas they spent less time upright...... from them; this was true both while lying (565 vs. 374min/d) and upright (276 vs. 223min/d). Self-grooming was seen significantly more near neighboring heifers than away from them (4.8 vs. 3.3% of time spent upright). When lying, cows more often positioned themselves in areas of the pen where...

  5. Capture and isolation of highly-charged ions in a unitary Penning trap

    CERN Document Server

    Brewer, Samuel M; Tan, Joseph N

    2013-01-01

    We recently used a compact Penning trap to capture and isolate highly-charged ions extracted from an electron beam ion trap (EBIT) at the National Institute of Standards and Technology (NIST). Isolated charge states of highly-stripped argon and neon ions with total charge $Q \\geq 10$, extracted at energies of up to $4\\times 10^3\\,Q$ eV, are captured in a trap with well depths of $\\,\\approx (4\\, {\\rm to}\\, 12)\\,Q$ eV. Here we discuss in detail the process to optimize velocity-tuning, capture, and storage of highly-charged ions in a unitary Penning trap designed to provide easy radial access for atomic or laser beams in charge exchange or spectroscopic experiments, such as those of interest for proposed studies of one-electron ions in Rydberg states or optical transitions of metastable states in multiply-charged ions. Under near-optimal conditions, ions captured and isolated in such rare-earth Penning traps can be characterized by an initial energy distribution that is $\\approx$ 60 times narrower than typically...

  6. Dose measurement in periapical radiographic exams using dosemeter pen: a look at the radioprotection

    Energy Technology Data Exchange (ETDEWEB)

    Oliveira, Renato; Ferreira, Vanessa, E-mail: vanessamachado@ufmg.br [Curso Superior de Tecnologia em Radiologia. Faculdade de Medicina. Universidade Federal de Minas Gerais, Belo Horizonte, MG (Brazil); Pereira, Claubia; Oliveira, Arno H.; Veloso, M.A.F., E-mail: gbarros@nuclear.ufmg.br, E-mail: claubia@nuclear.ufmg.br, E-mail: heeren@nuclear.ufmg.br, E-mail: Dora@nuclear.ufmg.br [Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG (Brazil). Dept. de Engenharia Nuclear

    2011-07-01

    The use of radiology has been a large increase with the crescent accessibility to dental care, orthodontics and aesthetic. Besides the increase in the number of exams, there was an increase in radiation dose during dental exams such as computed tomography. The objective of this work is to evaluate the radiation dose to which the patient is subjected in a peri apical dental radiography. The dose values were measured with a dosimeter pen during radiographs in real exams peri apical with the X-ray equipment Timex 70 C Gnatus. During the exams realization, was maintained, in the holder, the dosimeter pen near to the region of interest. The values collected were recorded in dosimeter pen. These values were compared with the reference doses of the Portaria 453 of ANVISA, this procedure allows to verify if the recommended dose limits for this exam are being respected. These data indicates if the used equipment is calibrated and in good condition of use. It was performed a comparison between the obtained experimental dose values and the values found from computer simulation with the code MCNPX 2.6.0. (author)

  7. Valorization of chitosan from squid pens and further use on the development of scaffolds for biomedical applications

    OpenAIRE

    Reys, L. L.; S.S. Silva; Oliveira, Joaquim M.; Frias, A. M.; Mano, J. F.; Silva, Tiago H.; Reis, R. L.

    2012-01-01

    Objectives: The aim of the present work is the valorization of squid pens through the production of chitosan that can be used for the development of biomedical applications. The present work is focused on !-chitin extraction from squid pens of the species Dosidicus gigas and its further conversion into chitosan. The biomedical potential of the isolated squid chitosan was assessed by processing this polymer as scaffolds for tissue engineering strategies. Methods: Alkali solut...

  8. Forensic Analysis of Blue Ball point Pen Inks Using Ultraviolet-Visible Spectrometer and Ultra-Performance Liquid Chromatograph

    International Nuclear Information System (INIS)

    Twelve varieties of blue ball point pens were selected and analyzed using UV-Vis spectrometer and ultra-performance liquid chromatography (UPLC). The aim of the study was to determine discrimination power (DP) of these methods in differentiating pen inks collected from the market in Malaysia. Discrimination analysis of 66 possible pen-pair of blue ball point pens was carried out via one-way ANOVA based on obtained chromatogram and spectra. A total of 18 peaks were determined as coming from inks based on the chromatographic data extracted at three different wavelengths (279, 370 and 400 nm). While for the UV-Vis spectrometer analysis, presence of peaks at 303, 545, 577 and 584 nm wavelengths were recorded. UV-Vis spectral data were mainly produced by the colorant components (for example, dyes) found in inks and UPLC may detect ink components other than dyes, for example, additives. As conclusion, the DP for UV-Vis and UPLC were determined to be 72.12 % and 98.48 %, respectively. This manuscript demonstrates the potential of UPLC for discriminating pen inks based on non-dye components. Additionally, the dye components in inks do not seem to play important role in discrimination of pen inks. (author)

  9. Propylthiouracil Attenuates Experimental Pulmonary Hypertension via Suppression of Pen-2, a Key Component of Gamma-Secretase.

    Directory of Open Access Journals (Sweden)

    Ying-Ju Lai

    Full Text Available Gamma-secretase-mediated Notch3 signaling is involved in smooth muscle cell (SMC hyper-activity and proliferation leading to pulmonary arterial hypertension (PAH. In addition, Propylthiouracil (PTU, beyond its anti-thyroid action, has suppressive effects on atherosclerosis and PAH. Here, we investigated the possible involvement of gamma-secretase-mediated Notch3 signaling in PTU-inhibited PAH. In rats with monocrotaline-induced PAH, PTU therapy improved pulmonary arterial hypertrophy and hemodynamics. In vitro, treatment of PASMCs from monocrotaline-treated rats with PTU inhibited their proliferation and migration. Immunocyto, histochemistry, and western blot showed that PTU treatment attenuated the activation of Notch3 signaling in PASMCs from monocrotaline-treated rats, which was mediated via inhibition of gamma-secretase expression especially its presenilin enhancer 2 (Pen-2 subunit. Furthermore, over-expression of Pen-2 in PASMCs from control rats increased the capacity of migration, whereas knockdown of Pen-2 with its respective siRNA in PASMCs from monocrotaline-treated rats had an opposite effect. Transfection of PASMCs from monocrotaline-treated rats with Pen-2 siRNA blocked the inhibitory effect of PTU on PASMC proliferation and migration, reflecting the crucial role of Pen-2 in PTU effect. We present a novel cell-signaling paradigm in which overexpression of Pen-2 is essential for experimental pulmonary arterial hypertension to promote motility and growth of smooth muscle cells. Propylthiouracil attenuates experimental PAH via suppression of the gamma-secretase-mediated Notch3 signaling especially its presenilin enhancer 2 (Pen-2 subunit. These findings provide a deep insight into the pathogenesis of PAH and a novel therapeutic strategy.

  10. Åpen programvare i offentlig sektor: Hva kreves for at åpne programvarer skal innføres i offentlig sektor?

    OpenAIRE

    Olsen, Ørjan

    2006-01-01

    Denne oppgaven er en casestudie om innføring av åpen programvare i offentlig sektor. Problemstillinger er: Hva kreves for at åpen programvare skal innføres i offentlig sektor? Min forskning er hovedsakelig basert på intervjuer i de tre styringsnivåer innen offentlig sektor som er involvert i arbeidet med åpen programvare. Dokumentasjon og noe observasjon er også brukt som datainnsamling. Litteraturen som omhandler åpen programvare er for det meste utenlandsk, men de beskriver godt hvordan si...

  11. Operational and theoretical temperature considerations in a Penning surface plasma source

    Energy Technology Data Exchange (ETDEWEB)

    Faircloth, D. C., E-mail: dan.faircloth@stfc.ac.uk; Lawrie, S. R. [ISIS Neutron and Muon Facility, STFC Rutherford Appleton Laboratory, Harwell Oxford, OX11 0QX (United Kingdom); Pereira Da Costa, H. [CERN, Geneva (Switzerland); Dudnikov, V. [Muons Inc. United States of America (United States)

    2015-04-08

    A fully detailed 3D thermal model of the ISIS Penning surface plasma source is developed in ANSYS. The proportion of discharge power applied to the anode and cathode is varied until the simulation matches the operational temperature observations. The range of possible thermal contact resistances are modelled, which gives an estimation that between 67% and 85% of the discharge power goes to the cathode. Transient models show the electrode surface temperature rise during the discharge pulse for a range of duty cycles. The implications of these measurements are discussed and a mechanism for governing cesium coverage proposed. The requirements for the design of a high current long pulse source are stated.

  12. Managing infertility with the follitropin alfa prefilled pen injector – patient considerations

    Directory of Open Access Journals (Sweden)

    Bühler K

    2015-06-01

    Full Text Available Klaus Bühler Centre for Gynaecological Endocrinology and Reproductive Medicine, Stuttgart, Germany Abstract: Gonadotropin treatment has been used in fertility treatment since the 1930s. First, preparations coming from animals were injected, then, gonadotropins prepared from the pituitary glands of human cadavers. A great step was achieved with the introduction of human menopausal gonadotropin extracted from the urine of postmenopausal women. When cases of Creutzfeld-Jacob disease were recognized after the use of human pituitary-derived hormone injections, urinary gonadotropins were increasingly purified and then produced by the use of recombinant DNA technology. Recombinant gonadotropins were characterized by the extreme high specificity and the nearly 100% purity. This allows for follitropin alfa, the first recombinant-human follicle stimulating hormone (r-hFSH approved, to be quantified and filled by mass, with a small variance of only ±2% and no more with a bioassay with a variance of 45%. With recombinant preparations, it is also possible to cover the tremendous growing demand for gonadotropins. Ovarian stimulation has become a self-injecting procedure for the patients. Accurate and easy-to-use injection devices which minimize pain, difficulty, and stress are essential for patient compliance. So, two pen injectors adapted from the well-known insulin pen were introduced in fertility treatment, one as a multiple-use device rechargeable with premixed, prefilled cartridges with r-hFSH (follitropin β and the other a disposable, prefilled drug delivery system with a liquid formulation of follitropin alfa filled by mass. The efficacy in comparison to the quite more cumbersome handling with ampoules and syringes has been proven very quickly. In several studies, it has been shown that patients had a preference to the prefilled follitropin alfa pen due to the faster preparation and were more confident of accurate dosing. The follitropin alfa

  13. Skin Blood Perfusion and Cellular Response to Insertion of Insulin Pen Needles With Different Diameters

    DEFF Research Database (Denmark)

    Præstmark, Kezia Ann; Stallknecht, Bente Merete; Bo Jensen, Casper;

    2014-01-01

    skin blood perfusion response around needle insertion sites. Three common sized pen needles of 28G, 30G, and 32G as well as hooked 32G needles, were inserted into the neck skin of pigs and then removed. Laser Speckle Contrast Analysis was used to measure skin blood perfusion for 20 minutes after...... the insertions. Seven pigs were included in the study and a total of 118 randomized needle insertions were conducted. Histology was made of tissue samples inserted with 18G, 28G, and 32G needles, and stained to quantify red and white blood cell response. Based on area under curve, calculated for each individual...

  14. PENTATRAP: A novel Penning-trap system for high-precision mass measurements

    OpenAIRE

    Dörr, A.

    2015-01-01

    The novel Penning-trap mass spectrometer PENTATRAP aims at mass-ratio determinations of medium-heavy to heavy ions with relative uncertainties below 10−11. From the mass ratios of certain ion species, the corresponding mass differences will be determined with sub-eV/c2uncertainties. These mass differences are relevant for neutrino-mass experiments, a test of special relativity and tests of bound-state QED. Means to obtain the required precision are very stable trapping fields, the use of high...

  15. Retroperitoneal migration of a self-inflicted ballpoint pen via the urethra

    Directory of Open Access Journals (Sweden)

    Jose Cury

    2006-04-01

    Full Text Available Numerous accounts documenting the introduction of foreign bodies into the urinary bladder have been reported. These foreign bodies are typically self-inserted via urethral but migration from adjacent organs by an ulcerative process and penetrating injuries are also reported. However, "contrary" migration of a self-inflicted vesical foreign body to the retroperitoneum was not previously reported in literature. We report here a case of a ballpoint pen self-inserted via urethral by a female patient, which was identified in retroperitoneal position years later.

  16. Gaze-shifting:direct-indirect input with pen and touch modulated by gaze

    OpenAIRE

    Pfeuffer, Ken; Alexander, Jason; Chong, Ming Ki; Zhang, Yanxia; Gellersen, Hans

    2015-01-01

    Modalities such as pen and touch are associated with direct input but can also be used for indirect input. We propose to combine the two modes for direct-indirect input modulated by gaze. We introduce gaze-shifting as a novel mechanism for switching the input mode based on the alignment of manual input and the user's visual attention. Input in the user's area of attention results in direct manipulation whereas input offset from the user's gaze is redirected to the visual target. The technique...

  17. Diagnosis of Hydrogen Plasma in a Miniature Penning Ion Source by Double Probes

    Institute of Scientific and Technical Information of China (English)

    JIN Dazhi; YANG Zhonghai; XIAO Kunxiang; DAI Jingyi

    2009-01-01

    Parameters of hydrogen plasma in a miniature Penning discharge ion source,including the electron temperature and the electron density,were measured by using double probes.The results indicate that the electron density increases and the electron temperature decreases with the increase in gas pressure and the discharge current.The electron temperature is about 5~9 eV and the electron density is 6.0x1013~1.2×1014 m-3 while the discharge current is in a range of 50~12μA.

  18. Fiber supercapacitors utilizing pen ink for flexible/wearable energy storage

    Energy Technology Data Exchange (ETDEWEB)

    Fu, Yongping; Cai, Xin; Wu, Hongwei; Lv, Zhibin; Hou, Shaocong; Peng, Ming; Yu, Xiao; Zou, Dechun [Beijing National Laboratory for Molecular Sciences, Key Laboratory of Polymer Chemistry and Physics of the Ministry of Education, College of Chemistry and Molecular Engineering, Peking University, Beijing (China)

    2012-11-08

    A novel type of flexible fiber/wearable supercapacitor that is composed of two fiber electrodes - a helical spacer wire and an electrolyte - is demonstrated. In the carbon-based fiber supercapacitor (FSC), which has high capacitance performance, commercial pen ink is directly utilized as the electrochemical material. FSCs have potential benefits in the pursuit of low-cost, large-scale, and efficient flexible/wearable energy storage systems. (Copyright copyright 2012 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  19. Phase space analysis for dynamics of three vortices of pure electron plasma trapped with Penning trap

    Energy Technology Data Exchange (ETDEWEB)

    Sanpei, Akio [Department of Electronics, Kyoto Institute of Technology, Goshokaido-cho, Matsugasaki, Sakyo Ward, Kyoto 606-8585 Japan (Japan); Soga, Yukihiro [Institute of Science and Engineering, Kanazawa University, Kakuma-machi, Kanazawa, Ishikawa 920-1192 Japan (Japan); Ito, Kiyokazu [Graduate School of Advanced Sciences of Matter, Hiroshima University, 1-3-1 Kagamiyama, Higashi-Hiroshima, Hiroshima 739-8530 Japan (Japan); Himura, Haruhiko [Department of Electronics, Kyoto Institute of Technology, Goshokaido-cho, Matsugasaki, Sakyo Ward, Kyoto 606-8585 (Japan)

    2015-06-29

    A trilinear phase space analysis is applied for dynamics of three electron clumps confined with a Penning-Malmberg trap. We show that the Aref’s concept of phase space describe the observed features of the dynamics of three point vortices qualitatively. In vacuum, phase point P moves to physical region boundary in phase space, i.e. triangular configuration cannot be kept. With the addition of a low level background vorticity distribution (BGVD), the excursion of the clumps is reduced and the distance between P and stable point does not extend in the phase space.

  20. Phase space analysis for dynamics of three vortices of pure electron plasma trapped with Penning trap

    International Nuclear Information System (INIS)

    A trilinear phase space analysis is applied for dynamics of three electron clumps confined with a Penning-Malmberg trap. We show that the Aref’s concept of phase space describe the observed features of the dynamics of three point vortices qualitatively. In vacuum, phase point P moves to physical region boundary in phase space, i.e. triangular configuration cannot be kept. With the addition of a low level background vorticity distribution (BGVD), the excursion of the clumps is reduced and the distance between P and stable point does not extend in the phase space

  1. Poly(-β-hydroxybutyrate) (PHB) depolymerase PHAZ Pen from Penicillium expansum: purification, characterization and kinetic studies

    OpenAIRE

    Gowda U. S., Vaishnavi; Shivakumar, Srividya

    2015-01-01

    Very few studies have been dedicated to R-hydroxyacids (R-HA) production using extracellular polyhydroxyalkanoate depolymerases (ePhaZs). Penicillium expansum produced maximum extracellular polyhydroxybutyrate depolymerase (~6 U/mL) by 72 h when grown in mineral salt medium containing 0.2 % w/v PHB, pH 5.0, at 30 °C and 200 rpm shaking conditions. Partial purification of the extracellular poly(-β-hydroxybutyrate) depolymerase PHAZ Pen from P. expansum by two steps using ammonium sulphate (80 ...

  2. JYFLTRAP: a cylindrical Penning trap for isobaric beam purification at IGISOL

    Energy Technology Data Exchange (ETDEWEB)

    Kolhinen, V.S.; Kopecky, S. E-mail: kopecky@phys.jyu.fi; Eronen, T.; Hager, U.; Hakala, J.; Huikari, J.; Jokinen, A.; Nieminen, A.; Rinta-Antila, S.; Szerypo, J.; Aeystoe, J

    2004-08-11

    A Penning trap has been installed for isobaric beam purification at the IGISOL-facility at the University of Jyvaeskylae. In this paper, the technical details of this new device together with results of the first tests are presented. The mass resolving power, depending on the excitation parameters and the ion species, can be as high as 145 000 and the total transmission has been determined to be 17%. In addition, it is shown that with this experimental setup it is possible to measure atomic masses up to A=120 with accuracies of approximately 50 keV.

  3. Mass measurements of neutron-deficient nuclides close to A=80 with a Penning trap

    Energy Technology Data Exchange (ETDEWEB)

    Kankainen, A.; Elomaa, V.-V.; Eronen, T.; Hager, U.; Hakala, J.; Jokinen, A.; Moore, I.; Penttilae, H.; Peraejaervi, K.; Rahaman, S.; Rinta-Antila, S.; Ronkanen, P.; Saastamoinen, A.; Sonoda, T.; Aeystoe, J. [University of Jyvaeskylae, Department of Physics, P.O. Box 35 (Finland); Batist, L.; Novikov, Yu.N.; Popov, A.V.; Seliverstov, D.M. [Petersburg Nuclear Physics Institute, Gatchina (Russian Federation); Eliseev, S.A.; Vorobjev, G.K. [Petersburg Nuclear Physics Institute, Gatchina (Russian Federation); GSI, Darmstadt (Germany)

    2006-09-15

    The masses of {sup 80,} {sup 81,} {sup 82,} {sup 83}Y, {sup 83,} {sup 84,} {sup 85,} {sup 86,} {sup 88}Zr and {sup 85,} {sup 86,} {sup 87,} {sup 88}Nb have been measured with a typical precision of 7keV by using the Penning trap setup at IGISOL. The mass of {sup 84}Zr has been measured for the first time. These precise mass measurements have improved S{sub p} and Q{sub EC} values for astrophysically important nuclides. (orig.)

  4. Capture and isolation of highly-charged ions in a unitary Penning trap

    OpenAIRE

    Brewer, Samuel M.; Nicholas D. Guise; Tan, Joseph N

    2013-01-01

    We recently used a compact Penning trap to capture and isolate highly-charged ions extracted from an electron beam ion trap (EBIT) at the National Institute of Standards and Technology (NIST). Isolated charge states of highly-stripped argon and neon ions with total charge $Q \\geq 10$, extracted at energies of up to $4\\times 10^3\\,Q$ eV, are captured in a trap with well depths of $\\,\\approx (4\\, {\\rm to}\\, 12)\\,Q$ eV. Here we discuss in detail the process to optimize velocity-tuning, capture, ...

  5. High-Accuracy Mass Determination of Unstable Nuclei with a Penning Trap Mass Spectrometer.

    CERN Multimedia

    2002-01-01

    The mass of a nucleus is its most fundamental property. A systematic study of nuclear masses as a function of neutron and proton number allows the observation of collective and single-particle effects in nuclear structure. Accurate mass data are the most basic test of nuclear models and are essential for their improvement. This is especially important for the astrophysical study of nuclear synthesis. In order to achieve the required high accuracy, the mass of ions captured in a Penning trap is determined via their cyclotron frequency $ \

  6. A clear atomic example for the surface sensitivity of penning ionization

    OpenAIRE

    Hotop, Hartmut; Ruf, Martin W.; Yencha, A.J.; Fricke, Burkhard

    1990-01-01

    Using a crossed-beam apparatus with a double hemispherical electron spectrometer, we have studied the spectrum of electrons released in thermal energy ionizing collisions of metastable He^*(2^3S) atoms with ground state Yb(4f^14 6s^2 ^1S_0) atoms, thereby providing the first Penning electron spectrum of an atomic target with-4f-electrons. In contrast to the HeI (58.4nm) and NeI (73.6/74.4nm) photoelectron spectra of Yb, which show mainly 4f- and 6s-electron emission in about a 5:1 ra...

  7. The Islamic connotation in the Gematric pen-names of Franqois Rabelais

    Directory of Open Access Journals (Sweden)

    Tine Kurent

    1991-12-01

    Full Text Available François Rabelais signed his books on Gargantua et Pantagruel with pen­ names. The gematric value of his pseudonyms, NASIER, M. ALCOFRIBAS, and ALCOFRIBAS NASIER, are 66, 99 and 152, respectively. With numbers 66 and 99, Rabelais identified himself as the Apocalyptic beast, according to the report by St, John the Divine: And I beheld another beast coming up out of the earth; and he had horns like a lamb. The ram's and buck's horns are indeed similar to the Indian figures 66 and 99.

  8. Forensic Analysis of Blue Ball point Pen Inks on Questioned Documents by High Performance Thin Layer Chromatography Technique (HPTLC)

    International Nuclear Information System (INIS)

    Nowadays, crimes related to forged documents are increasing. Any erasure, addition or modification in the document content always involves the use of writing instrument such as ball point pens. Hence, there is an evident need to develop a fast and accurate ink analysis protocol to solve this problem. This study is aimed to determine the discrimination power of high performance thin layer chromatography (HPTLC) technique for analyzing a set of blue ball point pen inks. Ink samples deposited on paper were extracted using methanol and separated via a solvent mixture of ethyl acetate, methanol and distilled water (70: 35: 30, v/ v/ v). In this method, the discrimination power of 89.40 % was achieved, which confirm that the proposed method was able to differentiate a significant number of pen-pair samples. In addition, composition of blue pen inks was found to be homogeneous (RSD < 2.5 %) and the proposed method showed good repeatability and reproducibility (RSD < 3. 0%). As a conclusion, HPTLC is an effective tool to separate blue ball point pen inks. (author)

  9. [Effects of large bio-manipulation fish pen on community structure of crustacean zooplankton in Meiliang Bay of Taihu Lake].

    Science.gov (United States)

    Ke, Zhi-Xin; Xie, Ping; Guo, Long-Gen; Xu, Jun; Zhou, Qiong

    2012-08-01

    In 2005, a large bio-manipulation pen with the stock of silver carp and bighead carp was built to control the cyanobacterial bloom in Meiliang Bay of Taihu Lake. This paper investigated the seasonal variation of the community structure of crustacean zooplankton and the water quality within and outside the pen. There were no significant differences in the environmental parameters and phytoplankton biomass within and outside the pen. The species composition and seasonal dynamics of crustacean zooplankton within and outside the pen were similar, but the biomass of crustacean zooplankton was greatly suppressed by silver carp and bighead carp. The total crustacean zooplankton biomass and cladocerans biomass were significantly lower in the pen (P carp and bighead carp exerted more pressure on cladoceran species than on copepod species. A distinct seasonal succession of crustacean zooplankton was observed in the Bay. Many crustacean species were only dominated in given seasons. Large-sized crustacean (mainly Daphnia sp. and Cyclops vicnus) dominated in winter and spring, while small-sized species (mainly Bosmina sp., Ceriodaphnia cornuta, and Limnoithona sinensis) dominated in summer and autumn. Canonical correspondence analysis showed that water transparency, temperature, and phytoplankton biomass were the most important factors affecting the seasonal succession of the crustacean. PMID:23189709

  10. Photophysical and photochemical effects of UV and VUV photo-oxidation and photolysis on PET and PEN

    Science.gov (United States)

    Morgan, Andrew

    Polyethylene Terephthalate (PET) is a widely used polymer in the bottling, packaging, and clothing industry. In recent years an increasing global demand for PET has taken place due to the Solar Disinfection (SODIS) process. SODIS is a method of sterilizing fresh water into drinkable water. The PET bottles are used in the process to contain the water during solar irradiation due to its highly transparent optical property. Alongside PET, polyethylene 2,6-napthalate (PEN) is used in bottling and flexible electronic applications. The surface of PEN would need to be modified to control the hydrophilicity and the interaction it exudes as a substrate. The UV light absorption properties of PET and PEN are of great importance for many applications, and thus needs to be studied along with its photochemical resistance. The optical and chemical nature of PET was studied as it was treated by UV photo-oxidation, photo-ozonation, and photolysis under atmospheric pressure. Another investigation was also used to study PEN and PET as they are treated by vacuum UV (VUV) photo-oxidation, VUV photolysis, and remote oxygen reactions. The extent of the photoreactions' effect into the depth of the polymers is examined as treatment conditions are changed. The different experimental methods established the rate of several competing photoreactions on PET and PEN during irradiance, and their effect on the optical quality of the polymers.

  11. Marker Pen Lithography for Flexible and Curvilinear On-Chip Energy Storage

    KAUST Repository

    Jiang, Qiu

    2015-07-14

    On-chip energy storage using microsupercapacitors can serve the dual role of supplementing batteries for pulse power delivery, and replacement of bulky electrolytic capacitors in ac-line filtering applications. Despite complexity and processing costs, microfabrication techniques are being employed in fabricating a great variety of microsupercapacitor devices. Here, a simple, cost-effective, and versatile strategy is proposed to fabricate flexible and curvilinear microsupercapacitors (MSCs). The protocol involves writing sacrificial ink patterns using commercial marker pens on rigid, flexible, and curvilinear substrates. It is shown that this process can be used in both lift-off and etching modes, and the possibility of multistack design of active materials using simple pen lithography is demonstrated. As a prototype, this method is used to produce conducting polymer MSCs involving both poly(3,4-ethylenedioxythiophene), polyaniline, and metal oxide (MnO2) electrode materials. Typical values of energy density in the range of 5-11 mWh cm-3 at power densities of 1-6 W cm-3 are achieved, which is comparable to thin film batteries and superior to the carbon and metal oxide based microsupercapacitors reported in the literature. The simplicity and broad scope of this innovative strategy can open up new avenues for easy and scalable fabrication of a wide variety of on-chip energy storage devices. © 2015 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim.

  12. Heritability of dimensions of Eysenck's pen model and the alternative five-factor model of personality

    Directory of Open Access Journals (Sweden)

    Smederevac Snežana

    2006-01-01

    Full Text Available The main aim of this study is to estimate the heritability of AFFM and PEN dimensions, including 67 pairs of twins (34 monozygotic and 33 dizygotic of both genders, aged 18 - 44. The heritability has been estimated by the biometric method, two full (ACE and ADE and three reduced (AE, DE and CE models tested for each personality trait. Taking into consideration the AFFM dimensions, additive genetic factors and a non-shared environment contribute the most significantly to the phenotypic variation of activity, sociability and the impulsive sensation seeking; anxiety and aggressiveness are best accounted for by the dominant genetic effects. In the PEN domain, fit indicators suggest that ACE and the reduced AE models provide the best explanation for the phenotypic manifestations of neuroticism, while ACE and CE models account for the variation of L scale. Although the fit indicators calculated for extraversion and psychotic behavior are somewhat problematic, the parameter estimates show that extraversion is best accounted for by the additive genetic variance, shared environmental effects, and the non-shared environment, whereas psychotic behavior is the most adequately explained by both shared and non-shared environmental effects.

  13. PENTATRAP. A novel Penning-trap system for high-precision mass measurements

    Energy Technology Data Exchange (ETDEWEB)

    Doerr, Andreas

    2015-01-21

    The novel Penning-trap mass spectrometer PENTATRAP aims at mass-ratio determinations of medium-heavy to heavy ions with relative uncertainties below 10{sup -11}. From the mass ratios of certain ion species, the corresponding mass differences will be determined with sub-eV/c{sup 2} uncertainties. These mass differences are relevant for neutrino-mass experiments, a test of special relativity and tests of bound-state QED. Means to obtain the required precision are very stable trapping fields, the use of highly-charged ions produced by EBITs, a non-destructive cyclotron-frequency determination scheme employing detectors with single-ion sensitivity and a five-trap tower, that allows for measurement schemes being insensitive to magnetic field drifts. Within this thesis, part of the detection electronics was set up and tested under experimental conditions. A single-trap setup was realized. A Faraday cup in the trap tower enabled the proper adjustment of the settings of the beamline connecting the EBIT and the Penning-trap system, resulting in the first trapping of ions at PENTATRAP. A stabilization of switched voltages in the beamline and detailed studies of ion bunch characteristics allowed for reproducible loading of only a few ions. Detection of the axial oscillation of the trapped ions gave hints that in some cases, even single ions had been trapped. Furthermore, valuable conclusions about necessary modifications of the setup could be drawn.

  14. Personality and Psychopathology: a Theory-Based Revision of Eysenck's PEN Model.

    Science.gov (United States)

    van Kampen, Dirk

    2009-12-08

    The principal aim of this paper is to investigate whether it is possible to create a personality taxonomy of clinical relevance out of Eysenck's original PEN model by repairing the various shortcomings that can be noted in Eysenck's personality theory, particularly in relation to P or Psychoticism. Addressing three approaches that have been followed to answer the question 'which personality factors are basic?', arguments are listed to show that particularly the theory-informed approach, originally defended by Eysenck, may lead to scientific progress. However, also noting the many deficiencies in the nomological network surrounding P, the peculiar situation arises that we adhere to Eysenck's theory-informed methodology, but criticize his theory. These arguments and criticisms led to the replacement of P by three orthogonal and theory-based factors, Insensitivity (S), Orderliness (G), and Absorption (A), that together with the dimensions E or Extraversion and N or Neuroticism, that were retained from Eysenck's PEN model, appear to give a comprehensive account of the main vulnerability factors in schizophrenia and affective disorders, as well as in other psychopathological conditions.

  15. Estructuras de fondo rehundido altomedievales en la Península Ibérica

    Directory of Open Access Journals (Sweden)

    TEJERIZO GARCÍA, C.

    2014-01-01

    Full Text Available La presencia de estructuras de fondo rehundido en contextos arqueológicos altomedievales está ampliamente documentada en toda Europa y cuenta con una dilatada historiografía. En la Península Ibérica, asociado a la expansión urbanística, se ha podido detectar un conjunto muy significativo de estas estructuras. Sin embargo, la falta de sistematización y análisis ha llevado a algunos problemas en su detección y documentación, así como a excesos conceptuales y de interpretación. En este trabajo se realiza una recopilación analítica de las evidencias de estructuras de fondo rehundido de época altomedieval presentes en la Península Ibérica mostrando su alta complejidad y diversidad. Basado en un análisis de la evidencia disponible, y frente a las tesis etnicistas que las vinculan a la llegada de grupos alóctonos, se propone una interpretación relacionada con el desarrollo de un modo de producción campesino tras la desarticulación de la economía imperial romana.

  16. Stocking density during the initial grow-out phase of tambatinga in net pens

    Directory of Open Access Journals (Sweden)

    Ana Paula Oeda Rodrigues

    2016-01-01

    Full Text Available ABSTRACT: The aim of this study was to determine the most adequate stocking density for tambatinga during the initial grow-out phase in net pens, considering fish growth, health, and financial aspects. Three stocking densities (400, 500, and 600 fish m-3 were evaluated for 60 days in a completely randomized design (n=4. There were no significant differences among the stocking densities for growth performance parameters, but yield was higher in the density of 600 fish m-3 (3,909.43±397.79kg m-3 compared to 400 fish m-3 (2,656.43±665.45kg m-3. Glucose, hematocrit, and total plasma proteins levels did not differ among treatments. The production was economically feasible for the three stocking densities. However, the density of 600 fish m-3 showed the highest profit. According to the results, 600 fish m-3 is the most adequate density for the initial grow-out phase of tambatinga in net pens.

  17. Decay study of neutron-rich zirconium isotopes employing a Penning trap as a spectroscopy tool

    Energy Technology Data Exchange (ETDEWEB)

    Rinta-Antila, S.; Eronen, T.; Elomaa, V.V.; Hager, U.; Hakala, J.; Jokinen, A.; Karvonen, P.; Penttilae, H.; Rissanen, J.; Sonoda, T.; Saastamoinen, A.; Aeystoe, J. [University of Jyvaeskylae, Department of Physics (Finland)

    2007-01-15

    A new technique to produce isobarically pure ion beams for decay spectroscopy by using a gas-filled Penning trap was commissioned at the ion guide isotope separator on-line facility, IGISOL. {beta}-decays of neutron-rich {sup 100}Zr, {sup 102}Zr and {sup 104}Zr isotopes were studied with this technique. In addition, the Q{sub {beta}{sup -}} values of {sup 100,102,104}Zr {beta}-decays were determined from the direct mass measurements of zirconium and niobium isotopes performed with a high-precision Penning trap. The mass of {sup 104}Nb was directly measured for the first time and the obtained mass excess value for the longer-living (1{sup +}) state is -71823{+-}10 keV. For the ground states of {sup 100}Nb and {sup 102}Nb the obtained mass excess values were -79802{+-}20 keV and -76309{+-}10 keV, respectively. The observed distribution of the {beta} strength supports a prolate deformation assignment for {sup 100,102,104}Zr isotopes. (orig.)

  18. Characteristics of deacetylation and depolymerization of β-chitin from jumbo squid (Dosidicus gigas) pens.

    Science.gov (United States)

    Jung, Jooyeoun; Zhao, Yanyun

    2011-09-27

    This study evaluated the deacetylation characteristics of β-chitin from jumbo squid (Dosidicus gigas) pens by using strongly alkaline solutions of NaOH or KOH. Taguchi design was employed to investigate the effect of reagent concentration, temperature, time, and treatment step on molecular mass (MM) and degree of deacetylation (DDA) of the chitosan obtained. The optimal treatment conditions for achieving high MM and DDA of chitosan were identified as: 40% NaOH at 90°C for 6h with three separate steps (2h+2h+2h) or 50% NaOH at 90°C for 6h with one step, or 50% KOH at 90°C for 4h with three steps (1h+1h+2h) or 6h with one step. The most important factor affecting DDA and MM was temperature and time, respectively. The chitosan obtained was then further depolymerized by cellulase or lysozyme with cellulase giving a higher degradation ratio, lower relative viscosity, and a larger amount of reducing-end formations than that of lysozyme due to its higher susceptibility. This study demonstrated that jumbo squid pens are a good source of materials to produce β-chitosan with high DDA and a wide range of MM for various potential applications. PMID:21700271

  19. Disposable pen-shaped capillary gel electrophoresis cartridge for fluorescence detection of bio-molecules

    Science.gov (United States)

    Amirkhanian, Varoujan; Tsai, Shou-Kuan

    2014-03-01

    We introduce a novel and cost-effective capillary gel electrophoresis (CGE) system utilizing disposable pen-shaped gelcartridges for highly efficient, high speed, high throughput fluorescence detection of bio-molecules. The CGE system has been integrated with dual excitation and emission optical-fibers with micro-ball end design for fluorescence detection of bio-molecules separated and detected in a disposable pen-shaped capillary gel electrophoresis cartridge. The high-performance capillary gel electrophoresis (CGE) analyzer has been optimized for glycoprotein analysis type applications. Using commercially available labeling agent such as ANTS (8-aminonapthalene-1,3,6- trisulfonate) as an indicator, the capillary gel electrophoresis-based glycan analyzer provides high detection sensitivity and high resolving power in 2-5 minutes of separations. The system can hold total of 96 samples, which can be automatically analyzed within 4-5 hours. This affordable fiber optic based fluorescence detection system provides fast run times (4 minutes vs. 20 minutes with other CE systems), provides improved peak resolution, good linear dynamic range and reproducible migration times, that can be used in laboratories for high speed glycan (N-glycan) profiling applications. The CGE-based glycan analyzer will significantly increase the pace at which glycoprotein research is performed in the labs, saving hours of preparation time and assuring accurate, consistent and economical results.

  20. Water and chloride transport in a fine-textured soil in a feedlot pen.

    Science.gov (United States)

    Veizaga, E A; Rodríguez, L; Ocampo, C J

    2015-11-01

    Cattle feeding in feedlot pens produces large amounts of manure and animal urine. Manure solutions resulting from surface runoff are composed of numerous chemical constituents whose leaching causes salinization of the soil profile. There is a relatively large number of studies on preferential flow characterization and modeling in clayed soils. However, research on water flow and solute transport derived from cattle feeding operations in fine-textured soils under naturally occurring precipitation events is less frequent. A field monitoring and modeling investigation was conducted at two plots on a fine-textured soil near a feedlot pen in Argentina to assess the potential of solute leaching into the soil profile. Soil pressure head and chloride concentration of the soil solution were used in combination with HYDRUS-1D numerical model to simulate water flow and chloride transport resorting to the concept of mobile/immobile-MIM water for solute transport. Pressure head sensors located at different depths registered a rapid response to precipitation suggesting the occurrence of preferential flow-paths for infiltrating water. Cracks and small fissures were documented at the field site where the % silt and % clay combined is around 94%. Chloride content increased with depth for various soil pressure head conditions, although a dilution process was observed as precipitation increased. The MIM approach improved numerical results at one of the tested sites where the development of cracks and macropores is likely, obtaining a more dynamic response in comparison with the advection-dispersion equation. PMID:26348833

  1. Water and chloride transport in a fine-textured soil in a feedlot pen

    Science.gov (United States)

    Veizaga, E. A.; Rodríguez, L.; Ocampo, C. J.

    2015-11-01

    Cattle feeding in feedlot pens produces large amounts of manure and animal urine. Manure solutions resulting from surface runoff are composed of numerous chemical constituents whose leaching causes salinization of the soil profile. There is a relatively large number of studies on preferential flow characterization and modeling in clayed soils. However, research on water flow and solute transport derived from cattle feeding operations in fine-textured soils under naturally occurring precipitation events is less frequent. A field monitoring and modeling investigation was conducted at two plots on a fine-textured soil near a feedlot pen in Argentina to assess the potential of solute leaching into the soil profile. Soil pressure head and chloride concentration of the soil solution were used in combination with HYDRUS-1D numerical model to simulate water flow and chloride transport resorting to the concept of mobile/immobile-MIM water for solute transport. Pressure head sensors located at different depths registered a rapid response to precipitation suggesting the occurrence of preferential flow-paths for infiltrating water. Cracks and small fissures were documented at the field site where the % silt and % clay combined is around 94%. Chloride content increased with depth for various soil pressure head conditions, although a dilution process was observed as precipitation increased. The MIM approach improved numerical results at one of the tested sites where the development of cracks and macropores is likely, obtaining a more dynamic response in comparison with the advection-dispersion equation.

  2. Ion bunch stacking in a Penning trap after purification in an electrostatic mirror trap

    CERN Document Server

    Rosenbusch, M; Blaum, K; Borgmann, Ch; Kreim, S; Lunney, D; Manea, V; Schweikhard, L; Wienholtz, F; Wolf, R N

    2014-01-01

    The success of many measurements in analytical mass spectrometry as well as in precision mass determinations for atomic and nuclear physics is handicapped when the ion sources deliver ``contaminations'', i.e., unwanted ions of masses similar to those of the ions of interest. In particular, in ion-trapping devices, large amounts of contaminant ions result in significant systematic errors-if the measurements are possible at all. We present a solution for such cases: The ions from a quasi-continuous source are bunched in a linear radio-frequency-quadrupole ion trap, separated by a multi-reflection time-of-flight section followed by a Bradbury-Nielsen gate, and then captured in a Penning trap. Buffer-gas cooling is used to damp the ion motion in the latter, which allows a repeated opening of the Penning trap for a stacking of mass-selected ion bunches. Proof-of-principle demonstrations have been performed with the ISOLTRAP setup at ISOLDE/CERN, both with Cs-133(+) ions from an off-line ion source and by applicati...

  3. Comparison of filters: Inkjet printed on PEN substrate versus a laser-etched on LCP substrate

    KAUST Repository

    Arabi, Eyad A.

    2014-10-01

    In this paper, microstrip-based bandpass filters on polyethylene naphthalate (PEN) and liquid crystal polymers (LCP) are presented to investigate the performance of filters on ultra-thin substrates. PEN (with a thickness of 120 μm) has been characterized and used for a filter for the first time. In addition to being low cost and transparent, it demonstrates comparable RF performance to LCP. The conductor losses are compared by fabricating filters with inkjet printed lines as well as laser etched copper clad LCP sheets. With 5 layers of inkjet printing, and a curing temperature below 200°C, a final silver thickness of 2 μm and conductivity of 9.6 × 106 S/m are achieved. The designs are investigated at two frequencies, 24 GHz as well as 5 GHz to assess their performance at high and low frequencies respectively. The 24 GHz inkjet printed filter shows an insertion loss of 2 dB, while the 5 GHz design gives an insertion loss of 8 dB. We find that thin substrates have a strong effect on the insertion loss of filters especially as the frequency is reduced. The same design, realized on LCP (thickness of 100 μm) through laser etching, demonstrates a very similar performance, thus verifying this finding. © 2014 European Microwave Association.

  4. Diphysa yucatanensis (Papilionoideae: Leguminosae), una especie nueva de la península de Yucatán

    OpenAIRE

    Ana Hanan A.; Mario Sousa S.

    2009-01-01

    Se describe e ilustra Diphysa yucatanensis como una especie nueva. Se distribuye en la península de Yucatán (Campeche, Quintana Roo, Yucatán, Belice y El Petén [Guatemala]) y zonas aledañas en Chiapas y Tabasco, México. Históricamente se le ha confundido con D. carthagenensis Jacq., la cual sólo recientemente ha sido encontrada en la parte más árida de la península.

  5. New Ceftriaxone- and Multidrug-Resistant Neisseria gonorrhoeae Strain with a Novel Mosaic penA Gene Isolated in Japan.

    Science.gov (United States)

    Nakayama, Shu-Ichi; Shimuta, Ken; Furubayashi, Kei-Ichi; Kawahata, Takuya; Unemo, Magnus; Ohnishi, Makoto

    2016-07-01

    We have characterized in detail a new ceftriaxone- and multidrug-resistant Neisseria gonorrhoeae strain (FC428) isolated in Japan in 2015. FC428 differed from previous ceftriaxone-resistant strains and contained a novel mosaic penA allele encoding a new mosaic penicillin-binding protein 2 (PBP 2). However, the resistance-determining 3'-terminal region of penA was almost identical to the regions of two previously reported ceftriaxone-resistant strains from Australia and Japan, indicating that both ceftriaxone-resistant strains and conserved ceftriaxone resistance-determining PBP 2 regions might spread. PMID:27067334

  6. New Ceftriaxone- and Multidrug-Resistant Neisseria gonorrhoeae Strain with a Novel Mosaic penA Gene Isolated in Japan.

    Science.gov (United States)

    Nakayama, Shu-Ichi; Shimuta, Ken; Furubayashi, Kei-Ichi; Kawahata, Takuya; Unemo, Magnus; Ohnishi, Makoto

    2016-07-01

    We have characterized in detail a new ceftriaxone- and multidrug-resistant Neisseria gonorrhoeae strain (FC428) isolated in Japan in 2015. FC428 differed from previous ceftriaxone-resistant strains and contained a novel mosaic penA allele encoding a new mosaic penicillin-binding protein 2 (PBP 2). However, the resistance-determining 3'-terminal region of penA was almost identical to the regions of two previously reported ceftriaxone-resistant strains from Australia and Japan, indicating that both ceftriaxone-resistant strains and conserved ceftriaxone resistance-determining PBP 2 regions might spread.

  7. Using the PEN-3 Model to Plan Culturally Competent Domestic Violence Intervention and Prevention Services in Chinese American and Immigrant Communities

    Science.gov (United States)

    Yick, Alice G.; Oomen-Early, Jody

    2009-01-01

    Purpose: The purpose of this article is two-fold. First, it applies the PEN-3 model to the topic of domestic violence within the Chinese American and Chinese immigrant community. The PEN-3 model was developed by Collins Airhihenbuwa, and it focuses on placing culture at the forefront of health promotion. It consists of three dimensions: cultural…

  8. 纳米复合塑料PET/PEN/NCL在啤酒瓶上的应用%Application of PET/PEN/NCL Nano-meter Composite to Beer Bottle

    Institute of Scientific and Technical Information of China (English)

    屈菊萍; 成战胜

    2006-01-01

    用对苯二甲酸二甲酯(DMT)与2,6-萘二甲酸二甲酯(DMN)两种单体,共缩聚为聚对苯二甲酸二乙醇酯(PET)和聚2,6-萘二甲酸二乙酯(PEN)共聚物.讨论了不同用量的纳米累托土(NCL)和PEN对共聚物PET/PEN/NCL及切片性能的影响.结果表明:纳米PET/PEN/NCL复合材料的合成工艺与普通聚酯切片的合成工艺相近,w(PEN)=6%、w(NCL)=3.0%的纳米啤酒瓶可耐105 ℃高温,对O2、CO2气体的阻隔性比PET瓶提高5~6倍,保质期可达5个月,运输和贮存比较安全,可满足工业需求.

  9. Benzene activation and H/D isotope effects in reactions of size selected iron, cobalt and nickel cluster ions

    Energy Technology Data Exchange (ETDEWEB)

    Merkert, Christine; Mohrbach, Jennifer; Tombers, Matthias; Barzen, Lars; Gaffga, Maximilian; Niedner-Schatteburg, Gereon [Fachbereich Chemie and Forschungszentrum OPTIMAS, Technische Universitaet Kaiserslautern, 67663 Kaiserslautern (Germany)

    2013-07-01

    A Penning ion trap served to investigate the reaction of size selected transition metal cluster ions in the size range 3FT-ICR) mass spectrometry on anionic and cationic iron, cobalt and nickel clusters. Kinetic Isotope Effects KIE(n) in total reaction rates are inverse, Dehydrogenation Isotope Effects DIE(n) are predominantly normal. A multistep model of adsorption and stepwise dehydrogenation from the precursor adsorbate proves suitable to rationalize the found KIEs and DIEs in principle.

  10. Identification of amino acids conferring high-level resistance to expanded-spectrum cephalosporins in the penA gene from Neisseria gonorrhoeae strain H041.

    Science.gov (United States)

    Tomberg, Joshua; Unemo, Magnus; Ohnishi, Makoto; Davies, Christopher; Nicholas, Robert A

    2013-07-01

    The recent identification of a high-level-ceftriaxone-resistant (MIC = 2 to 4 μg/ml) isolate of Neisseria gonorrhoeae from Japan (H041) portends the loss of ceftriaxone as an effective treatment for gonococcal infections. This is of grave concern because ceftriaxone is the last remaining option for first-line empirical antimicrobial monotherapy. The penA gene from H041 (penA41) is a mosaic penA allele similar to mosaic alleles conferring intermediate-level cephalosporin resistance (Ceph(i)) worldwide but has 13 additional mutations compared to the mosaic penA gene from the previously studied Ceph(i) strain 35/02 (penA35). When transformed into the wild-type strain FA19, the penA41 allele confers 300- and 570-fold increases in the MICs for ceftriaxone and cefixime, respectively. In order to understand the mechanisms involved in high-level ceftriaxone resistance and to improve surveillance and epidemiology during the potential emergence of ceftriaxone resistance, we sought to identify the minimum number of amino acid alterations above those in penA35 that confer high-level resistance to ceftriaxone. Using restriction fragment exchange and site-directed mutagenesis, we identified three mutations, A311V, T316P, and T483S, that, when incorporated into the mosaic penA35 allele, confer essentially all of the increased resistance of penA41. A311V and T316P are close to the active-site nucleophile Ser310 that forms the acyl-enzyme complex, while Thr483 is predicted to interact with the carboxylate of the β-lactam antibiotic. These three mutations have thus far been described only for penA41, but dissemination of these mutations in other mosaic alleles would spell the end of ceftriaxone as an effective treatment for gonococcal infections.

  11. Cold-water coral mounds on the Pen Duick Escarpment, Gulf of Cadiz: The MiCROSYSTEMS project approach

    NARCIS (Netherlands)

    Van Rooij, D.; Blamart, D.; De Mol, L.; Mienis, F.; Pirlet, H.; Wehrmann, L. M.; Barbieri, R.; Maignien, L.; Templer, S. P.; de Haas, H.; Hebbeln, D.; Frank, N.; Larmagnat, S.; Stadnitskaia, A.; Stivaletta, N.; van Weering, T.; Zhang, Y.; Hamoumi, N.; Cnudde, V.; Duyck, P.; Henriet, J.-P.; The MiCROSYSTEMS MD 169 Shipboard Party

    2011-01-01

    Here we present a case study of three cold-water coral mounds in a juvenile growth stage on top of the Pen Duick Escarpment in the Gulf of Cadiz; Alpha, Beta and Gamma mounds. Although cold-water corals are a common feature on the adjacent cliffs, mud volcanoes and open slope, no actual living cold-

  12. Comparing the Use of the Interpersonal Computer, Personal Computer and Pen-and-Paper When Solving Arithmetic Exercises

    Science.gov (United States)

    Alcoholado, Cristián; Diaz, Anita; Tagle, Arturo; Nussbaum, Miguel; Infante, Cristián

    2016-01-01

    This study aims to understand the differences in student learning outcomes and classroom behaviour when using the interpersonal computer, personal computer and pen-and-paper to solve arithmetic exercises. In this multi-session experiment, third grade students working on arithmetic exercises from various curricular units were divided into three…

  13. Dip-Pen Nanolithography on (Bio)Reactive Monolayer and Block-Copolymer Platforms: Deposition of Lines of Single Macromolecules

    NARCIS (Netherlands)

    Salazar, Ramon B.; Shovsky, Alexander; Schönherr, Holger; Vancso, G. Julius

    2006-01-01

    The application of atomic force microscopy (AFM) tip-mediated molecular transfer (dip-pen nanolithography or DPN) to fabricate nanopatterned (bio)reactive platforms based on dendrimers on reactive self-assembled monolayer (SAM) and polymer thin films is discussed. The transfer of high-molar-mass pol

  14. Aportaciones a la flora vascular del norte de la Península Ibérica

    Directory of Open Access Journals (Sweden)

    Fidalgo, E., Llorente, A., Cadiñanos, J.A., Tarruella, J.

    2012-01-01

    Full Text Available Se citan varios taxones nuevos o interesantes de la flora vascular del norte de la Península Ibérica, concretamente de las provincias vascas de Álava, Vizcaya y Guipúzcoa y de las comunidades de Cantabria, Asturias, Castilla-León y Navarra.

  15. 9 CFR 309.7 - Livestock affected with anthrax; cleaning and disinfection of infected livestock pens and driveways.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Livestock affected with anthrax... INSPECTION § 309.7 Livestock affected with anthrax; cleaning and disinfection of infected livestock pens and driveways. (a) Any livestock found on ante-mortem inspection to be affected with anthrax shall be...

  16. Full color flexible top-emission AMOLED display on polyethylene naphthalate (PEN) foil with metal oxide TFTs backplane

    NARCIS (Netherlands)

    Fukui, Y.; Shibata, M.; Tanaka, Y.; Okumoto, K.; Morita, K.; Otake, K.; Tripathi, A.K.; Putten, B. van der; Steen, J.L. van der; Tempelaars, K.; Leuken, L. van; Li, F.; Yakimets, I.; Gelinck, G.H.; Myny, K.; Smout, S.; Willegems, M.; Schols, S.; Steudel, S.; Genoe, J.; Heremans, P.

    2013-01-01

    We have developed a full color flexible top-emission AMOLED display with 80 ppi resolution using In-Ga-Zn-O TFT backplane on PEN foil under the maximum process temperature of 150 oC. Notwithstanding the low processing temperature, the TFTs with SiOx passivation layer show high reliability with VTH s

  17. 9 CFR 72.17 - Unloading noninfected cattle for rest, feed, and water only, permitted in authorized pens for...

    Science.gov (United States)

    2010-01-01

    ... TRANSPORTATION OF ANIMALS (INCLUDING POULTRY) AND ANIMAL PRODUCTS TEXAS (SPLENETIC) FEVER IN CATTLE § 72.17... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Unloading noninfected cattle for rest, feed, and water only, permitted in authorized pens for such purpose. 72.17 Section 72.17 Animals...

  18. 9 CFR 72.11 - Quarantined area; cattle considered infested; requirements for placing in noninfectious pens or...

    Science.gov (United States)

    2010-01-01

    ... TRANSPORTATION OF ANIMALS (INCLUDING POULTRY) AND ANIMAL PRODUCTS TEXAS (SPLENETIC) FEVER IN CATTLE § 72.11... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Quarantined area; cattle considered infested; requirements for placing in noninfectious pens or premises. 72.11 Section 72.11 Animals...

  19. 9 CFR 313.50 - Tagging of equipment, alleyways, pens, or compartments to prevent inhumane slaughter or handling...

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Tagging of equipment, alleyways, pens, or compartments to prevent inhumane slaughter or handling in connection with slaughter. 313.50 Section 313.50 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF...

  20. Analysis of the burden of treatment in patients receiving an EpiPen for yellow jacket anaphylaxis

    NARCIS (Netherlands)

    Elberink, Joanne N. G. Oude; van der Heide, S.; Guyatt, Gordon H.; Dubois, Anthony E. J.

    2006-01-01

    Background: Venom immunotherapy (VIT) is a treatment with established efficacy for the prevention of repeated anaphylactic reactions in patients with Hymenoptera allergy, which also allows patients to discontinue carrying an EpiPen. Despite their merits, both treatments can have negative aspects pot

  1. Pen-mate directed behaviour in ad libitum fed pigs given different quantities and frequencies of straw

    DEFF Research Database (Denmark)

    Amdi, C.; Lahrmann, H.P.; Oxholm, L.C.;

    2015-01-01

    is expensive. In addition, straw needs to remain fresh in order to have a degree of novelty. The aim of this study was to investigate pen-mate directed behaviour in pigs given different straw treatments. Pigs were assigned to one of five treatments testing either quantity or frequency of chopped......-mate directed behaviour were recorded. In addition, residual straw in the pens was assessed using four categories ranging from straw in a thin layer; little straw; few straws; and soiled straw. Pigs were active for about 30% of the registered time, but overall no differences in total pen-mate directed behaviour...... pigs were active for about 30% of the day corresponding to less than 5 h per day. Of the active time, an average of 17 min was spent on pen-mate directed behaviour. Only minor differences were found in the residual straw assessment, T25 had a higher percentage of little straw left compared to T50 and T...

  2. WITCH a Penning trap retardation spectrometer combination for precision studies of the weak interaction

    CERN Document Server

    Delauré, B J; Golovko, V V; Kozlov, V Yu; Phalet, T; Schuurmans, P; Severijns, N; Vereecke, B; Versyck, S; Beck, D; Quint, W; Ames, F; Reisinger, K; Forstner, O; Deutsch, J; Bollen, G; Schwarz, S

    2003-01-01

    The weak interaction trap for charged particles (WITCH) setup is being installed at the ISOLDE facility (CERN) to test the Standard Model of the electroweak interaction. This will be done by searching for scalar and tensor admixtures in nuclear $\\beta$-decay. The $\\beta$-neutrino angular correlation is an excellent probe to determine the possible strength of those non-Standard Model contributions. The WITCH setup combines the unique storage features of a Penning trap to produce a scattering free radioactive source with a retardation spectrometer to measure the recoil energy spectrum of the daughter nuclei after $\\beta$-decay with high precision. Physics beyond the Standard Model would lead to deviations from the expected spectral shape. (7 refs).

  3. A study on flow characteristics of fountain-pen nano-lithography with active membrane pumping

    International Nuclear Information System (INIS)

    In this study, the flow characteristics of a FPN (Fountain Pen Nano-Lithography) using active membrane pumping are investigated. The FPN has integrated chamber, micro channel, and high capacity reservoir for continuous ink feed. The most important aspect in this probe provided control of fluid injection using active membrane pumping in chamber. The flow rates in channel by capillary force are theoretically analyzed, including the control of the mass flow rates by the deflection of the membrane. The above results are compared with the numerical simulations that calculated by commercial code, FLUENT. The velocity of the fluid in micro channel shows linear behaviors. And the mass flows are proportional to the second order function of the pumping pressure that is imposed to the membrane

  4. University Mentoring with the Support of a Digital Pen and Hypermedia Resources

    Directory of Open Access Journals (Sweden)

    Manuel Francisco Aguilar Tamayo

    2014-12-01

    Full Text Available This paper systematizes face-to-face tutoring experience and the use of technologies to make audio and written recordings of tutorial sessions with undergraduate, master’s and doctoral students available online. One hundred and three tutorial sessions with 26 students and a single tutor are analyzed; the sessions were recorded by means of a digital pen that recorded sound and writing synchronously. By means of this analysis students’ issues and problems were identified and a model for connecting teaching strategy and the production of hypermedia resources is presented. We contend that it is important to create learning resources to accompany the educational process of tutees. In conclusion the study presents a model for organizing and supporting university level tutoring.

  5. La "etnicidad marginal" de las comunas de la península de Santa Elena, Ecuador

    Directory of Open Access Journals (Sweden)

    Martín Bazurco

    2005-06-01

    Full Text Available Las comunas de la Península de Santa Elena representan la continuidad histórica de las antiguas jefaturas Manteño - Huancavilcas. Estas comunas han logrado mantener el control de su territorio y una relativa autonomía socio-económica a lo largo de todo el período colonial y republicano, poniendo en práctica diversas estrategias de articulación con la sociedad dominante. Sin embargo, la supervivencia de estas comunidades se debate, hoy en día, entre las agresiones extemas a su temitodo, y su "etnicidad marginal" que las excluye del marco constitucional ecuatoriano destinado a la protección de los tenitorios étnicos. A continuación se analiza el proceso de resignificación de la diversidad al que están abocadas las comunas de la PSE.

  6. Simbuca, using a graphics card to simulate Coulomb interactions in a penning trap

    CERN Document Server

    Van Gorp, S; Friedag, P; De Leebeeck, V; Tandecki, M; Weinheimer, C; Breitenfeldt, M; Traykov, E; Severijn, N; Mader, J; Soti, G; Iitaka, T; Herlert, A; Wauters, F; Zakoucky, D; Kozlov, V; Roccia, S

    2011-01-01

    In almost all cases, N-body simulations are limited by the computation time available. Coulomb interaction calculations scale with O(N(2)) with N the number of particles. Approximation methods exist already to reduce the computation time to O(NlogN) although calculating the interaction still dominates the total simulation time. We present Simbuca, a simulation package for thousands of ions moving in a Penning trap which will be applied for the WITCH experiment. Simbuca uses the output of the Cunbody-1 library, which calculates the gravitational interaction between entities on a graphics card, and adapts it for Coulomb calculations. Furthermore the program incorporates three realistic buffer gas models, the possibility of importing realistic electric and magnetic fieldmaps and different order integrators with adaptive step size and error control. The software is released under the GNU General Public License and free for use. Crown Copyright (C) 2010 Published by Elsevier B.V. All rights reserved.

  7. Simbuca, using a graphics card to simulate Coulomb interactions in a penning trap

    Energy Technology Data Exchange (ETDEWEB)

    Van Gorp, S., E-mail: simon.vangorp@fys.kuleuven.b [Instituut voor Kern- en Stralingsfysica, K.U.Leuven, Celestijnenlaan 200D, B-3001 Leuven (Belgium); Beck, M. [Universitaet Muenster, Institut fuer Kernphysik, Wilhelm-Klemm-Strasse 9, D-48149 Muenster (Germany); Breitenfeldt, M.; De Leebeeck, V. [Instituut voor Kern- en Stralingsfysica, K.U.Leuven, Celestijnenlaan 200D, B-3001 Leuven (Belgium); Friedag, P. [Universitaet Muenster, Institut fuer Kernphysik, Wilhelm-Klemm-Strasse 9, D-48149 Muenster (Germany); Herlert, A. [CERN, CH-1211 Geneve 23 (Switzerland); Iitaka, T. [Computational Astrophysics Laboratory, RIKEN, 2-1 Hirosawa, Wako, Saitama 351-0198 (Japan); Mader, J. [Universitaet Muenster, Institut fuer Kernphysik, Wilhelm-Klemm-Strasse 9, D-48149 Muenster (Germany); Kozlov, V. [Karlsruhe Institute of Technology, Institut fuer Kernphysik, Postfach 3640, D-76021 Karlsruhe (Germany); Roccia, S.; Soti, G.; Tandecki, M.; Traykov, E.; Wauters, F. [Instituut voor Kern- en Stralingsfysica, K.U.Leuven, Celestijnenlaan 200D, B-3001 Leuven (Belgium); Weinheimer, Ch. [Universitaet Muenster, Institut fuer Kernphysik, Wilhelm-Klemm-Strasse 9, D-48149 Muenster (Germany); Zakoucky, D. [Nuclear Physics Institute, ASCR, CZ-250 68 Rez (Czech Republic); Severijns, N. [Instituut voor Kern- en Stralingsfysica, K.U.Leuven, Celestijnenlaan 200D, B-3001 Leuven (Belgium)

    2011-05-11

    In almost all cases, N-body simulations are limited by the computation time available. Coulomb interaction calculations scale with O(N{sup 2}) with N the number of particles. Approximation methods exist already to reduce the computation time to O(NlogN), although calculating the interaction still dominates the total simulation time. We present Simbuca, a simulation package for thousands of ions moving in a Penning trap which will be applied for the WITCH experiment. Simbuca uses the output of the Cunbody-1 library, which calculates the gravitational interaction between entities on a graphics card, and adapts it for Coulomb calculations. Furthermore the program incorporates three realistic buffer gas models, the possibility of importing realistic electric and magnetic fieldmaps and different order integrators with adaptive step size and error control. The software is released under the GNU General Public License and free for use.

  8. Cylindrical Penning traps with dynamic orthogonalized anharmonicity compensation for precision experiments

    CERN Document Server

    Fei Xiang

    1999-01-01

    Harmonic potentials can be produced in cylindrical ion traps by means of dynamic orthogonalized anharmonicity compensation with use of two (or multiple) sets of compensation electrodes. One special example is for traps with multiple identical electrodes which are not only easy to construct and allow access to the center region of the trap for particle loading and releasing, laser beams, and microwaves, but also flexible in forming harmonic potential wells in many locations. The nested trap configuration and the side-by-side trap configuration are readily available in this special scheme. Analytical solutions for cylindrical traps with multiple sets of compensation potentials are presented. This work will be useful for studies involving Penning trap diagnostics, atomic and molecular interactions (including the production of antihydrogen atoms), accurate mass measurements of exotic particles, and precision measurements of the spin precession frequencies of trapped particles.

  9. Profile measurements in the plasma edge of MAST using a ball pen probe

    CERN Document Server

    Walkden, N R; Allan, S; Dudson, B D; Elmore, S; Fishpool, G; Harrison, J; Kirk, A; Komm, M

    2014-01-01

    The ball pen probe (BPP) technique is used successfully to make profile measurements of plasma potential, electron temperature and radial electric field on the Mega Amp Spherical Tokamak (MAST). The potential profile measured by the BPP is shown to significantly differ from the floating potential both in polarity and profile shape. By combining the BPP potential and the floating potential the electron temperature can be measured, which is compared with the Thomson scattering (TS) diagnostic. Excellent agreement between the two diagnostics is obtained when secondary electron emission is accounted for in the floating potential. From the BPP profile an estimate of the radial electric field is extracted which is shown to be of the order ~1kV/m and increases with plasma current. Corrections to the BPP measurement, constrained by the TS comparison, introduce uncertainty into the ER measurements. The uncertainty is most significant in the electric field well inside the separatrix. The electric field is used to estim...

  10. Customizing Properties of β-Chitin in Squid Pen (Gladius by Chemical Treatments

    Directory of Open Access Journals (Sweden)

    Alessandro Ianiro

    2014-12-01

    Full Text Available The squid pen (gladius from the Loligo vulgaris was used for preparation of β-chitin materials characterized by different chemical, micro- and nano-structural properties that preserved, almost completely the macrostructural and the mechanical ones. The β-chitin materials obtained by alkaline treatment showed porosity, wettability and swelling that are a function of the duration of the treatment. Microscopic, spectroscopic and synchrotron X-ray diffraction techniques showed that the chemical environment of the N-acetyl groups of the β-chitin chains changes after the thermal alkaline treatment. As a consequence, the crystalline packing of the β-chitin is modified, due to the intercalation of water molecules between β-chitin sheets. Potential applications of these β-chitin materials range from the nanotechnology to the regenerative medicine. The use of gladii, which are waste products of the fishing industry, has also important environmental implications.

  11. Les deux faces de la pensée de E.A. Martel

    OpenAIRE

    Jacques Choppy

    1997-01-01

    Réunion de textes de Martel: 1 - Extraits du Nouveau Traité des Eaux Souterraines (1921), donnant l’essentiel de la pensée de l’auteur sur l’hydraulique et la morphologie du karst. 2 - En opposition à cette vision, rappelée de nombreuses fois par l’auteur, extraits de diverses publications (de 1894 à 1930), admettant qu’un fonctionnement en régime noyé était possible: Martel est donc l’un des tout premiers ayant observé des formes de creusement en régime noyé, et les ayant interprétées comme ...

  12. In situ electromagnetic field diagnostics with an electron plasma in a Penning-Malmberg trap

    CERN Document Server

    Amole, C; Baquero-Ruiz, M.; Bertsche, W.; Butler, E.; Capra, A.; Cesar, C.L.; Charlton, M.; Deller, A.; Evetts, N.; Eriksson, S.; Fajans, J.; Friesen, T.; Fujiwara, M.C.; Gill, D.R.; Gutierrez, A.; Hangst, J.S.; Hardy, W.N.; Hayden, M.E.; Isaac, C.A.; Jonsell, S.; Kurchaninov, L.; Little, A.; Madsen, N.; McKenna, J.T.K.; Menary, S.; Napoli, S.C.; Olchanski, K.; Olin, A.; Pusa, P.; Rasmussen, C.; Robicheaux, F.; Sarid, E.; Silveira, D.M.; So, C.; Stracka, S.; Tharp, T.; Thompson, R.I.; van der Werf, D.P.; Wurtele, J.S.

    2014-01-01

    We demonstrate a novel detection method for the cyclotron resonance frequency of an electron plasma in a Penning-Malmberg trap. With this technique, the electron plasma is used as an in situ diagnostic tool for measurement of the static magnetic field and the microwave electric field in the trap. The cyclotron motion of the electron plasma is excited by microwave radiation and the temperature change of the plasma is measured non-destructively by monitoring the plasma's quadrupole mode frequency. The spatially-resolved microwave electric field strength can be inferred from the plasma temperature change and the magnetic field is found through the cyclotron resonance frequency. These measurements were used extensively in the recently reported demonstration of resonant quantum interactions with antihydrogen.

  13. Development of educational software for beam loading analysis using pen-based user interfaces

    Directory of Open Access Journals (Sweden)

    Yong S. Suh

    2014-01-01

    Full Text Available Most engineering software tools use typical menu-based user interfaces, and they may not be suitable for learning tools because the solution processes are hidden and students can only see the results. An educational tool for simple beam analyses is developed using a pen-based user interface with a computer so students can write and sketch by hand. The geometry of beam sections is sketched, and a shape matching technique is used to recognize the sketch. Various beam loads are added by sketching gestures or writing singularity functions. Students sketch the distributions of the loadings by sketching the graphs, and they are automatically checked and the system provides aids in grading the graphs. Students receive interactive graphical feedback for better learning experiences while they are working on solving the problems.

  14. Suppression of the e- coextracted from a Penning surface-plasma H- source

    International Nuclear Information System (INIS)

    The ratio of electrons to negative ions extracted from Penning surface-plasma sources (SPS) such as the 8X source is low even before any steps are taken to suppress the electrons. For the 8X source the e-/H- ratio is typically four or five to one for H- operation and nine to one for D- operation. Because the coextracted e- present a power-loading problem to the 8X source extraction system, methods to dissipate and/or reduce the power in the e- beam must be developed before extracting a dc H- or D- beam. Thus, an experiment was run to see if a collar installed in the near extraction region of the 8X source suppresses the electrons extracted from that source

  15. An ultra-stable voltage source for precision Penning-trap experiments

    Science.gov (United States)

    Böhm, Ch.; Sturm, S.; Rischka, A.; Dörr, A.; Eliseev, S.; Goncharov, M.; Höcker, M.; Ketter, J.; Köhler, F.; Marschall, D.; Martin, J.; Obieglo, D.; Repp, J.; Roux, C.; Schüssler, R. X.; Steigleder, M.; Streubel, S.; Wagner, Th.; Westermann, J.; Wieder, V.; Zirpel, R.; Melcher, J.; Blaum, K.

    2016-08-01

    An ultra-stable and low-noise 25-channel voltage source providing 0 to -100 V has been developed. It will supply stable bias potentials for Penning-trap electrodes used in high-precision experiments. The voltage source generates all its supply voltages via a specially designed transformer. Each channel can be operated either in a precision mode or can be dynamically ramped. A reference module provides reference voltages for all the channels, each of which includes a low-noise amplifier to gain a factor of 10 in the output stage. A relative voltage stability of δV / V ≈ 2 ×10-8 has been demonstrated at -89 V within about 10 min.

  16. Penning trap assisted decay spectroscopy of neutron-rich {sup 115}Ru

    Energy Technology Data Exchange (ETDEWEB)

    Kurpeta, J.; Plochocki, A.; Urban, W. [Warsaw University, Faculty of Physics, Warsaw (Poland); Elomaa, V.V.; Eronen, T.; Hakala, J.; Jokinen, A.; Karvonen, P.; Moore, I.; Penttilae, H.; Rahaman, S.; Rinta-Antila, S.; Rissanen, J.; Ronkainen, J.; Saastamoinen, A.; Sonoda, T.; Weber, C.; Aeystoe, J. [University of Jyvaeskylae, Department of Physics (Finland)

    2007-03-15

    Exotic, neutron-rich {sup 111}Mo and {sup 115}Ru nuclei, produced in proton-induced fission of {sup 238}U target, were separated with the IGISOL mass separator. The separator was coupled to the JYFLTRAP Penning trap to select the ions of a single, desired element out of the isobaric IGISOL beam. Monoisotopic samples of {sup 115}Ru and {sup 111}Mo ions were observed with a microchannel plate detector after the trap or were implanted on a catcher foil for gamma- and beta-ray coincidence spectroscopy. In spite of short data taking time new gamma transitions were identified in the beta decay of very neutron-rich {sup 115}Ru. (orig.)

  17. JYFLTRAP: a penning trap for precision mass spectroscopy and isobaric purification

    Energy Technology Data Exchange (ETDEWEB)

    Eronen, T.; Kolhinen, V.S.; Elomaa, V.V.; Gorelov, D.; Hager, U.; Hakala, J.; Jokinen, A.; Kankainen, A.; Karvonen, P.; Kopecky, S.; Moore, I.D.; Penttilae, H.; Rahaman, S.; Rinta-Antila, S.; Rissanen, J.; Saastamoinen, A.; Szerypo, J.; Weber, C.; Aeystoe, J. [University of Jyvaeskylae, Jyvaeskylae (Finland)

    2012-04-15

    In this article a comprehensive description and performance of the double Penning-trap setup JYFLTRAP will be detailed. The setup is designed for atomic mass measurements of both radioactive and stable ions and additionally serves as a very high-resolution mass separator. The setup is coupled to the IGISOL facility at the accelerator laboratory of the University of Jyvaeskylae. The trap has been online since 2003 and it was shut down in the summer of 2010 for relocation to the upgraded IGISOL facility. Numerous atomic mass and decay energy measurements have been performed using the time-of-flight ion-cyclotron resonance technique. The trap has also been used in several decay spectroscopy experiments as a high-resolution mass filter. (orig.)

  18. Communication: Importance of rotationally inelastic processes in low-energy Penning ionization of CHF3

    Science.gov (United States)

    Jankunas, Justin; Jachymski, Krzysztof; Hapka, Michał; Osterwalder, Andreas

    2016-06-01

    Low energy reaction dynamics can strongly depend on the internal structure of the reactants. The role of rotationally inelastic processes in cold collisions involving polyatomic molecules has not been explored so far. Here we address this problem by performing a merged-beam study of the He(3S1)+CHF3 Penning ionization reaction in a range of collision energies E/kB = 0.5-120 K. The experimental cross sections are compared with total reaction cross sections calculated within the framework of quantum defect theory. We find that the broad range of collision energies combined with the relatively small rotational constants of CHF3 makes rotationally inelastic collisions a crucial player in the total reaction dynamics. Quantitative agreement between theory and experiment is only obtained if the energy-dependent probability for rotational excitation is included in the calculations, in stark contrast to previous experiments where classical scaling laws were able to describe the results.

  19. Photoassociation spectroscopy in Penning ionization reactions at sub-Kelvin temperatures

    CERN Document Server

    Skomorowski, Wojciech; Narevicius, Edvardas; Koch, Christiane P

    2016-01-01

    Penning ionization reactions in merged beams with precisely controlled collision energies have been shown to accurately probe quantum mechanical effects in reactive collisions. A complete microscopic understanding of the reaction is, however, faced with two major challenges---the highly excited character of the reaction's entrance channel and the limited precision of even the best state-of-the-art ab initio potential energy surfaces. Here, we suggest photoassociation spectroscopy as a tool to identify the character of orbiting resonances in the entrance channel and probe the ionization width as a function of inter-particle separation. We introduce the basic concept and discuss the general conditions under which this type of spectroscopy will be successful.

  20. Importance of rotationally inelastic processes in low-energy Penning ionization of CHF$_3$

    CERN Document Server

    Jankunas, Justin; Hapka, Michał; Osterwalder, Andreas

    2016-01-01

    Low energy reaction dynamics can strongly depend on the internal structure of the reactants. The role of rotationally inelastic processes in cold collisions involving polyatomic molecules has not been explored so far. Here we address this problem performing a merged-beam study of the He*+CHF$_3$ Penning ionization reaction in a range of collision energies $E/k_B$=0.5--120 K. The experimental cross sections are compared with total reaction cross sections calculated within the framework of the quantum defect theory. We find that the broad range of collision energies combined with the relatively small rotational constants of \\chfs makes rotationally inelastic collisions a crucial player in the total reaction dynamics. Quantitative agreement between theory and experiment is only obtained if the energy-dependent probability for rotational excitation is included in the calculations, in stark contrast to previous experiments where classical scaling laws were able to describe the results.

  1. Development and Evaluation of Disaster Information Management System Using Digital Pens and Tabletop User Interfaces

    Science.gov (United States)

    Fukada, Hidemi; Kobayashi, Kazue; Satou, Kenji; Kawana, Hideyuki; Masuda, Tomohiro

    Most traditional disaster information systems are necessary to post expert staff with high computer literacy to operate the system quickly and correctly in the tense situation when a disaster occurs. However, in the current disaster response system of local governments, it is not easy for local governments to post such expert staff because they are struggling with staff cuts due to administrative and fiscal reform. In this research, we propose a disaster information management system that can be easily operated, even under the disorderly conditions of a disaster, by municipal personnel in charge of disaster management. This system achieves usability enabling easy input of damage information, even by local government staff with no expertise, by using a digital pen and tabletop user interface. Evaluation was conducted by prospective users using a prototype, and the evaluation results are satisfactory with regard to the function and operationality of the proposed system.

  2. Paper-pen peer-correction versus wiki-based peer-correction

    Directory of Open Access Journals (Sweden)

    Froldova Vladimira

    2016-01-01

    Full Text Available This study reports on the comparison of the students’ achievement and their attitudes towards the use of paper-pen peer-correction and wiki-based peer-correction within English language lessons and CLIL Social Science lessons at the higher secondary school in Prague. Questionnaires and semi-structured interviews were utilized to gather information. The data suggests that students made considerable use of wikis and showed higher degrees of motivation in wiki-based peer-correction during English language lessons than in CLIL Social Science lessons. In both cases wikis not only contributed to developing students’ writing skills, but also helped students recognize the importance of collaboration.

  3. Discharge characteristics of a penning ion source for compact neutron generator

    Science.gov (United States)

    Liu, Weibo; Li, Mingjuan; Gao, Kun; Gu, Deshan

    2014-12-01

    We investigate the discharge characteristics of a penning ion source for a compact sealed neutron generator in DC mode. A measuring system consisting of console, vacuum gauges, and teslameter is established. By using the measuring system, the discharge current as a function of ion source voltage, gas pressure, and magnetic field is studied. The results show that the neutron generator can operate in a safe and steady state when the experimental parameters are as follows: ion source voltage of 1.2-2 kV, gas pressure of 4×10-2-8×10-2 Pa, and magnetic field of 0.3-0.5 T. Within these ranges, the neutron yield of the generator can reach 2×108 n/s.

  4. Discharge characteristics of a penning ion source for compact neutron generator

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Weibo, E-mail: liuwb_1108@163.com [Department of Opto-Electronic Engineering, Binzhou University, Binzhou 256603 (China); Li, Mingjuan [Flying College, Binzhou University, Binzhou 256603 (China); Gao, Kun [Department of Opto-Electronic Engineering, Binzhou University, Binzhou 256603 (China); Gu, Deshan [School of Physics, Northeast Normal University, Changchun 130024 (China)

    2014-12-21

    We investigate the discharge characteristics of a penning ion source for a compact sealed neutron generator in DC mode. A measuring system consisting of console, vacuum gauges, and teslameter is established. By using the measuring system, the discharge current as a function of ion source voltage, gas pressure, and magnetic field is studied. The results show that the neutron generator can operate in a safe and steady state when the experimental parameters are as follows: ion source voltage of 1.2–2 kV, gas pressure of 4×10{sup −2}–8×10{sup −2} Pa, and magnetic field of 0.3–0.5 T. Within these ranges, the neutron yield of the generator can reach 2×10{sup 8} n/s.

  5. Accuracy studies with carbon clusters at the Penning trap mass spectrometer TRIGA-TRAP

    Science.gov (United States)

    Ketelaer, J.; Beyer, T.; Blaum, K.; Block, M.; Eberhardt, K.; Eibach, M.; Herfurth, F.; Smorra, C.; Nagy, Sz.

    2010-05-01

    Extensive cross-reference measurements of well-known frequency ratios using various sizes of carbon cluster ions 12Cn + (10≤n≤23) were performed to determine the effects limiting the accuracy of mass measurements at the Penning-trap facility TRIGA-TRAP. Two major contributions to the uncertainty of a mass measurement have been identified. Fluctuations of the magnetic field cause an uncertainty in the frequency ratio due to the required calibration by a reference ion of uf(νref)/νref = 6(2) × 10-11/min × Δt. A mass-dependent systematic shift of the frequency ratio of epsilonm(r)/r = -2.2(2) × 10-9 × (m-mref)/u has been found as well. Finally, the nuclide 197Au was used as a cross-check since its mass is already known with an uncertainty of 0.6 keV.

  6. Development of miniaturized, spectroscopically assisted Penning gauges for fractional helium and hydrogen neutral pressure measurements

    Science.gov (United States)

    Flesch, K.; Kremeyer, T.; Schmitz, O.; Soukhanovskii, V.; Wenzel, U.

    2016-11-01

    Direct measurements of the helium (He) fractional neutral pressure in the neutral gas around fusion devices is challenging because of the small mass difference between the abundant D2 molecules and the He ash which will be produced by deuterium-tritium fusion. To study He exhaust, an in situ Penning gauge system is being developed at UW-Madison that is optimized for good pressure and high spectroscopic sensitivity. Three different anode geometries have been studied regarding their vacuum electrostatic fields, light output, and ion current. The light output of the two new anode configurations are at least one order of magnitude above the currently available designs, hence improving the spectroscopic sensitivity at similar total neutral pressure resolution.

  7. A novel squid pen chitosan/hydroxyapatite/β-tricalcium phosphate composite for bone tissue engineering

    International Nuclear Information System (INIS)

    Squid pen chitosan was used in the fabrication of biocomposite scaffolds for bone tissue engineering. Hydroxyapatite (HA) and beta-tricalcium phosphate (β-TCP) obtained from waste mussel shells were used as the calcium phosphate source. The composite was prepared using 2.5% tripolyphosphate (TPP) and 1% glycerol as a cross-linker and plasticizer, respectively. The weight percent (wt.%) ratios of the ceramic components in the composite were 20/10/70, 30/20/50 and 40/30/30 (HA/β-TCP/Chi). The biodegradation rate and structural properties of the scaffolds were investigated. Scanning electron microscopy (SEM) and microCT(μCT) results indicated that the composites have a well defined lamellar structure with an average pore size of 200 μm. The porosity of the composites decreased from 88 to 56% by increasing the ratio of HA/β-TCP from 30 to 70%. After 28 days of incubation in a physiological solution, the scaffolds were degraded by approximately 30%. In vitro investigations showed that the composites were cytocompatible and supported the growth of L929 and Saos-2 cells. The obtained data suggests that the squid pen chitosan composites are potential candidates for bone regeneration. - Highlights: • Biocomposite scaffolds were made from mussel shells HA and β-TCP, and squid pin chitosan. • The porosity of the composites decreased with an increase in HA/β-TCP ratio. • Composites were cytocompatible and supported the growth of L929 and Saos-2 cells. • Composite containing 50% HA and β-TCP had the best mechanical properties

  8. MEMS-enabled Dip Pen Nanolithography for directed nanoscale deposition and high-throughput nanofabrication

    Science.gov (United States)

    Haaheim, J. R.; Nafday, O. A.; Levesque, T.; Fragala, J.; Shile, R.

    2009-02-01

    Precision nanoscale deposition is a fundamental requirement for nanoscience research, development, and commercial implementation. Dip Pen Nanolithography(R) (DPN) is an inherently additive SPM-based technique which operates under ambient conditions, making it suitable to deposit a wide range of biological and inorganic materials. This technique is fundamentally enabled by a portfolio of MEMS devices tailored for microfluidic ink delivery, directed placement of nanoscale materials via actuated cantilevers, and cm2 tip arrays for high-throughput nanofabrication. Multiplexed deposition of nanoscale materials is a challenging problem, but we have implemented InkWells(TM) to enable selective delivery of ink materials to different tips in multiple probe arrays, while preventing cross-contamination. Active Pens(TM) can take advantage of this, directly place a variety of materials in nanoscale proximity, and do so in a "clean" fashion since the cantilevers can be manipulated in Z. Further, massively parallel two-dimensional nanopatterning with DPN is now commercially available via NanoInk's 2D nano PrintArray(TM), making DPN a highthroughput, flexible and versatile method for precision nanoscale pattern formation. By fabricating 55,000 tip-cantilevers across a 1 cm2 chip, we leverage the inherent versatility of DPN and demonstrate large area surface coverage, routinely achieving throughputs of 3×107 μm2 per hour. Further, we have engineered the device to be easy to use, wire-free, and fully integrated with the NSCRIPTOR's scanner, stage, and sophisticated lithography routines. In this talk we discuss the methods of operating this commercially available device, and subsequent results showing sub-100 nm feature sizes and excellent uniformity (standard deviation portfolio including: 1) rapidly and flexibly generating nanostructures; 2) chemically directed assembly and 3) directly writing biological materials.

  9. First direct mass measurements on nobelium and lawrencium with the Penning trap mass spectrometer SHIPTRAP

    Energy Technology Data Exchange (ETDEWEB)

    Dworschak, Michael Gerhard

    2009-12-08

    The Penning trap mass spectrometer SHIPTRAP at GSI Darmstadt was set up for high-precision mass measurements of heavy radionuclides produced in fusion evaporation reactions and separated from the primary beam by the velocity filter SHIP. It consists of a gas stopping cell for the deceleration of the high energetic reaction products, an RFQ cooler and buncher for cooling and accumulation of the ions, and a double Penning trap system to perform mass measurements. The mass is determined by measuring the cyclotron frequency of the ion of interest in a strong homogeneous magnetic field and comparing it to the frequency of a well-known reference ion. With this method relative uncertainties in the order of 10{sup -8} can be achieved. Recently, mass measurements of the three nobelium isotopes {sup 252-254}No (Z=102) and the lawrencium isotope {sup 255}Lr (Z=103) were performed successfully. These were the first direct mass measurements of transuranium elements ever per- formed. The production rate of the atoms of interest was about one per second or less. The results of the measurements on nobelium confirm the previous mass values which were deduced from Q{sub {alpha}} values. In the case of {sup 255}Lr the mass excess value, which was previously only estimated from systematic trends, was for the first time directly measured. These results mark the first step in the exploration of the region of transuranium elements which is planned at SHIPTRAP. The main objective is to fix the endpoints of {alpha} decay chains which are originating from superheavy elements close to the predicted island of stability. (orig.)

  10. Neonatal piglet traits of importance for survival in crates and indoor pens.

    Science.gov (United States)

    Pedersen, L J; Berg, P; Jørgensen, G; Andersen, I L

    2011-04-01

    The primary aim of the present study was to investigate whether the same piglet traits contributed to the same causes of neonatal piglet mortality in crates (CT) and pens (PN). Gilts originating from 2 distinct genetic groups that differed in breeding value for piglet survival rate at d 5 (SR5) were used. These were distributed to farrow in either PN or CT as follows: high-SR5 and CT (n = 30); low-SR5 and CT (n = 27); high-SR5 and PN (n = 22); and low-SR5 and PN (n = 24). Data on individual piglets were collected at birth, including interbirth interval; birth order; birth weight; rectal temperature at birth, 2 h after birth, and 24 h after birth; cordal plasma lactate; and latency to first suckle. Based on autopsy, causes of mortality were divided into stillborn, bitten to death, starvation, crushed, disease, and other causes. Potential risk factors of dying were estimated using a GLM with a logit link function. No significant effect (NS) of housing was observed on the odds of a piglet being stillborn (F(1,73) = 0.1, NS), being crushed (F(1,53) = 1.4, NS), or dying of starvation (F(1,53) = 0.3, NS). No significant differences were observed between the 2 genetic groups for any category of mortality. Piglet traits for pre- and postnatal survival were the same for CT and PN. The odds of being stillborn were increased in piglets born late in the birth order (F(1,1061) = 33.5, P piglets, the greater were the odds of being crushed (F(1,1050) = 18, P piglets. The results emphasize that the microclimate in the PN for newborn piglets and its heat-preserving properties are more important for survival than whether the sow is crated or penned.

  11. A novel squid pen chitosan/hydroxyapatite/β-tricalcium phosphate composite for bone tissue engineering

    Energy Technology Data Exchange (ETDEWEB)

    Shavandi, Amin, E-mail: amin.shavandi@postgrad.otago.ac.nz [Department of Food Sciences, University of Otago, Dunedin (New Zealand); Department of Applied Sciences, University of Otago, Dunedin (New Zealand); Bekhit, Alaa El-Din A. [Department of Food Sciences, University of Otago, Dunedin (New Zealand); Sun, Zhifa; Ali, Azam [Department of Physics, University of Otago, Dunedin (New Zealand); Gould, Maree [Department of Anatomy, University of Otago, Dunedin (New Zealand)

    2015-10-01

    Squid pen chitosan was used in the fabrication of biocomposite scaffolds for bone tissue engineering. Hydroxyapatite (HA) and beta-tricalcium phosphate (β-TCP) obtained from waste mussel shells were used as the calcium phosphate source. The composite was prepared using 2.5% tripolyphosphate (TPP) and 1% glycerol as a cross-linker and plasticizer, respectively. The weight percent (wt.%) ratios of the ceramic components in the composite were 20/10/70, 30/20/50 and 40/30/30 (HA/β-TCP/Chi). The biodegradation rate and structural properties of the scaffolds were investigated. Scanning electron microscopy (SEM) and microCT(μCT) results indicated that the composites have a well defined lamellar structure with an average pore size of 200 μm. The porosity of the composites decreased from 88 to 56% by increasing the ratio of HA/β-TCP from 30 to 70%. After 28 days of incubation in a physiological solution, the scaffolds were degraded by approximately 30%. In vitro investigations showed that the composites were cytocompatible and supported the growth of L929 and Saos-2 cells. The obtained data suggests that the squid pen chitosan composites are potential candidates for bone regeneration. - Highlights: • Biocomposite scaffolds were made from mussel shells HA and β-TCP, and squid pin chitosan. • The porosity of the composites decreased with an increase in HA/β-TCP ratio. • Composites were cytocompatible and supported the growth of L929 and Saos-2 cells. • Composite containing 50% HA and β-TCP had the best mechanical properties.

  12. El Grupo Trinity Peninsula en la península Tabarin, extremo norte de la península Antártica

    Directory of Open Access Journals (Sweden)

    R.A. del Valle

    2007-12-01

    Full Text Available La península Tabarin, Antártida Occidental, exhibe rocas deformadas durante los ciclos orogénicos gondwánico y ándico. La Formación Hope Bay y Formación Düse Bay (Carbonífero tardío-Triásico están incluidas dentro del Grupo Trinity Peninsula, registrando el ciclo orogénico gondwánico. Las estructuras sedimentarias, asociaciones de facies y rasgos deposicionales de la Formación Hope Bay, sugieren sedimentación en ambientes marinos someros. La presencia de capas calcáreas con morfología build-up y matas calcáreas, y rocas piroclásticas, incluyendo ignimbritas, peperitas y depósitos ricos es escoria volcánica, también indican escasa profundidad del mar para la sedimentación de la Formación Düse Bay. El área de aporte del Grupo Trinity Peninsula estaba compuesta por rocas volcánicas y plutónicas con cantidades menores de rocas sedimentarias y metamórficas, probablemente ubicadas hacia el este para la parte inferior Formación Hope Bay de la secuencia, y hacia el oeste para la parte superior de la Formación Düse Bay, con mayor participación volcánica en el último caso. El ambiente de sedimentación más probable para la Formación Hope Bay fue una plataforma silícicoclástica somera y de baja energía, y una cuenca de retroarco de antepaís, relacionada con la orogenia gondwánica, en el caso de la Formación Düse Bay.

  13. Speech understanding in noise with the Roger Pen, Naida CI Q70 processor, and integrated Roger 17 receiver in a multi-talker network.

    Science.gov (United States)

    De Ceulaer, Geert; Bestel, Julie; Mülder, Hans E; Goldbeck, Felix; de Varebeke, Sebastien Pierre Janssens; Govaerts, Paul J

    2016-05-01

    Roger is a digital adaptive multi-channel remote microphone technology that wirelessly transmits a speaker's voice directly to a hearing instrument or cochlear implant sound processor. Frequency hopping between channels, in combination with repeated broadcast, avoids interference issues that have limited earlier generation FM systems. This study evaluated the benefit of the Roger Pen transmitter microphone in a multiple talker network (MTN) for cochlear implant users in a simulated noisy conversation setting. Twelve post-lingually deafened adult Advanced Bionics CII/HiRes 90K recipients were recruited. Subjects used a Naida CI Q70 processor with integrated Roger 17 receiver. The test environment simulated four people having a meal in a noisy restaurant, one the CI user (listener), and three companions (talkers) talking non-simultaneously in a diffuse field of multi-talker babble. Speech reception thresholds (SRTs) were determined without the Roger Pen, with one Roger Pen, and with three Roger Pens in an MTN. Using three Roger Pens in an MTN improved the SRT by 14.8 dB over using no Roger Pen, and by 13.1 dB over using a single Roger Pen (p processor to take advantage of the Roger system. The listening advantage and ease of use should encourage more clinicians to recommend and fit Roger in adult cochlear implant patients. PMID:25983309

  14. Amplification of an MFS Transporter Encoding Gene penT Significantly Stimulates Penicillin Production and Enhances the Sensitivity of Penicillium chrysogenum to Phenylacetic Acid

    Institute of Scientific and Technical Information of China (English)

    Jing Yang; Xinxin Xu; Gang Liu

    2012-01-01

    Penicillin is historically important as the first discovered drug against bacterial infections in human.Although the penicillin biosynthetic pathway and regulatory mechanism have been well studied in Penicillium chrysogenum,the compartnentation and molecular transport of penicillin or its precursors are still poorly understood.In search of the genomic database,more than 830 open reading frames (ORFs) were found to encode transmembrane proteins of P.chrysogenum.In order to investigate their roles on penicillin production,one of them (penT) was selected and cloned.The deduced protein of penT belongs to the major facilitator superfamily (MFS) and contains 12transmembrane spanning domains (TMS).During fermentation,the transcription of penT was greatly induced by penicillin precursors phenylacetic acid (PAA) and phenoxyacetic acid (POA).Knock-down of penT resulted in significant decrease of penicillin production,while over-expression of penT under the promoter of trpC enhanced the penicillin production.Introduction of an additional penT in the wild-type strain of P.chrysogenum doubled the penicillin production and enhanced the sensitivity of P.chrysogenum to the penicillin precursors PAA or POA.These results indicate that penT stimulates penicillin production probably through enhancing the translocation of penicillin precursors across fungal cellular membrane.

  15. Simplicity, safety, and acceptability of insulin pen use versus the conventional vial/syringe device in patients with type 1 and type 2 diabetes mellitus in Lebanon

    Science.gov (United States)

    Ramadan, Wijdan H; Khreis, Noura A; Kabbara, Wissam K

    2015-01-01

    Background The aim of the study was to evaluate the simplicity, safety, patients’ preference, and convenience of the administration of insulin using the pen device versus the conventional vial/syringe in patients with diabetes. Methods This observational study was conducted in multiple community pharmacies in Lebanon. The investigators interviewed patients with diabetes using an insulin pen or conventional vial/syringe. A total of 74 questionnaires were filled over a period of 6 months. Answers were entered into the Statistical Package for Social Sciences (SPSS) software and Excel spreadsheet. t-test, logistic regression analysis, and correlation analysis were used in order to analyze the results. Results A higher percentage of patients from the insulin pen users group (95.2%) found the method easy to use as compared to only 46.7% of the insulin conventional users group (P 0.001, relative risk [RR]: 2.041, 95% confidence interval [CI]: 1.178–3.535). Moreover, 61.9% and 26.7% of pen users and conventional users, respectively, could read the scale easily (P 0.037, RR 2.321, 95% CI: 0.940–5.731), while 85.7% of pen users found it more convenient shifting to pen and 86.7% of the conventional users would want to shift to pen if it had the same cost. Pain perception was statistically different between the groups. A much higher percentage (76.2%) of pen users showed no pain during injection compared to only 26.7% of conventional users (P 0.003, RR 2.857, 95% CI: 1.194–6.838). Conclusion The insulin pen was significantly much easier to use and less painful than the conventional vial/syringe. Proper education on the methods of administration/storage and disposal of needles/syringes is needed in both groups. PMID:25848231

  16. Utjecaj različitih profilaktičkih pasta i vremena čišćenja na DIAGNOdent/DIAGNOdent pen-vrijednosti

    OpenAIRE

    Dukić, Walter; Vindakijević, Željka; Lulić Dukić, Olga; Milardović, Slađana

    2007-01-01

    Svrha: Svrha rada bila je analizirati utjecaj uporabe različitih profilaktičkih pasta na vrijednosti očitanja DIAGNOdent/DIAGNOdent-penom (DD/DD pen) i utjecaj različitih vremena i tehnika ispiranja ostataka pasta na očitanje DD/DD pen-vrijednosti. Također je trebalo ustanoviti postoje li razlike u očitanju vrijednosti između DD i DD pen-uređaja. Materijal i postupci: Na 35 zdravih trajnih trećih molara DD/DD penuređajima izmjerene su referentne vrijednosti te su odabrani zubi čije vrijed...

  17. NeuroPigPen: A Scalable Toolkit for Processing Electrophysiological Signal Data in Neuroscience Applications Using Apache Pig.

    Science.gov (United States)

    Sahoo, Satya S; Wei, Annan; Valdez, Joshua; Wang, Li; Zonjy, Bilal; Tatsuoka, Curtis; Loparo, Kenneth A; Lhatoo, Samden D

    2016-01-01

    The recent advances in neurological imaging and sensing technologies have led to rapid increase in the volume, rate of data generation, and variety of neuroscience data. This "neuroscience Big data" represents a significant opportunity for the biomedical research community to design experiments using data with greater timescale, large number of attributes, and statistically significant data size. The results from these new data-driven research techniques can advance our understanding of complex neurological disorders, help model long-term effects of brain injuries, and provide new insights into dynamics of brain networks. However, many existing neuroinformatics data processing and analysis tools were not built to manage large volume of data, which makes it difficult for researchers to effectively leverage this available data to advance their research. We introduce a new toolkit called NeuroPigPen that was developed using Apache Hadoop and Pig data flow language to address the challenges posed by large-scale electrophysiological signal data. NeuroPigPen is a modular toolkit that can process large volumes of electrophysiological signal data, such as Electroencephalogram (EEG), Electrocardiogram (ECG), and blood oxygen levels (SpO2), using a new distributed storage model called Cloudwave Signal Format (CSF) that supports easy partitioning and storage of signal data on commodity hardware. NeuroPigPen was developed with three design principles: (a) Scalability-the ability to efficiently process increasing volumes of data; (b) Adaptability-the toolkit can be deployed across different computing configurations; and (c) Ease of programming-the toolkit can be easily used to compose multi-step data processing pipelines using high-level programming constructs. The NeuroPigPen toolkit was evaluated using 750 GB of electrophysiological signal data over a variety of Hadoop cluster configurations ranging from 3 to 30 Data nodes. The evaluation results demonstrate that the toolkit

  18. Usability of devices for self-injection: results of a formative study on a new disposable pen injector

    Directory of Open Access Journals (Sweden)

    Lange J

    2014-06-01

    Full Text Available Jakob Lange,1 Philipp Richard,1 Nick Bradley21Ypsomed AG, Burgdorf, Switzerland; 2Bergo, Glasgow, United KingdomAbstract: This article presents a late-stage formative usability study of a pen-injector platform device. Such devices are used for the subcutaneous delivery of biopharmaceuticals, primarily for self-administration by the patient. The study was conducted with a broad user population, defined to represent user characteristics across a range of indications. The goals of the study were to confirm that the pen could be used without recurring patterns of use errors leading to hazardous situations, to evaluate the comprehension of the instructions for use (IFU, and to determine if training is necessary. In the study, a total of 36 participants in six groups (health care providers, caregivers, adolescents, diabetics with retinopathy, diabetics with neuropathy, and patients with arthritis each read the IFU, prepared the device, and performed two simulated injections into an injection pad. Any use errors, near misses, or deviations from the IFU procedure were recorded. The overall success rate (injection completed by the participant without need for assistance was 94% for the first and 100% for the second injection. Ninety-two percent of the participants reported that they felt confident using the device, 100% found the IFU helpful, and 75% found the device positively comfortable to use. Overall, a total average of 3.35 deviations and errors per user and injection were recorded (there were no near misses. Subtracting the errors without any potential for negative consequences for the injection or the user (trivial deviations, as well as those related to attaching and removing the pen needle (independent of the design of the pen itself, led to an average of 1.31 potentially relevant deviations per user and injection. It was concluded that the pen injector together with the IFU could be safely and efficiently used by all user groups without any

  19. Deep-sea pennatulaceans (sea pens) - recent discoveries, morphological adaptations, and responses to benthic oceanographic parameters

    Science.gov (United States)

    Williams, G. C.

    2015-12-01

    Pennatulaceans are sessile, benthic marine organisms that are bathymetrically wide-ranging, from the intertidal to approximately 6300 m in depth, and are conspicuous constituents of deep-sea environments. The vast majority of species are adapted for anchoring in soft sediments by the cylindrical peduncle - a muscular hydrostatic skeleton. However, in the past decade a few species ("Rockpens") have been discovered and described that can attach to hard substratum such as exposed rocky outcrops at depths between 669 and 1969 m, by a plunger-like adaptation of the base of the peduncle. Of the thirty-six known genera, eleven (or 30%) have been recorded from depths greater than 1000 m. The pennatulacean depth record holders are an unidentified species of Umbellula from 6260 m in the Peru-Chile Trench and a recently-discovered and described genus and species, Porcupinella profunda, from 5300 m the Porcupine Abyssal Plain of the northeastern Atlantic. A morphologically-differentiated type of polyp (acrozooid) have recently been discovered and described in two genera of shallow-water coral reef sea pens. Acrozooids apparently represent asexual buds and presumably can detach from the adult to start clonal colonies through asexual budding. Acrozooids are to be expected in deep-sea pennatulaceans, but so far have not been observed below 24 m in depth. Morphological responses at depths greater than 1000 m in deep-sea pennatulaceas include: fewer polyps, larger polyps, elongated stalks, and clustering of polyps along the rachis. Responses to deep-ocean physical parameters and anthropogenic changes that could affect the abundance and distribution of deep-sea pennatulaceans include changes in bottom current flow and food availability, changes in seawater temperature and pH, habitat destruction by fish trawling, and sunken refuse pollution. No evidence of the effects of ocean acidification or other effects of anthropogenic climate change in sea pens of the deep-sea has been

  20. Neonatal piglet traits of importance for survival in crates and indoor pens.

    Science.gov (United States)

    Pedersen, L J; Berg, P; Jørgensen, G; Andersen, I L

    2011-04-01

    The primary aim of the present study was to investigate whether the same piglet traits contributed to the same causes of neonatal piglet mortality in crates (CT) and pens (PN). Gilts originating from 2 distinct genetic groups that differed in breeding value for piglet survival rate at d 5 (SR5) were used. These were distributed to farrow in either PN or CT as follows: high-SR5 and CT (n = 30); low-SR5 and CT (n = 27); high-SR5 and PN (n = 22); and low-SR5 and PN (n = 24). Data on individual piglets were collected at birth, including interbirth interval; birth order; birth weight; rectal temperature at birth, 2 h after birth, and 24 h after birth; cordal plasma lactate; and latency to first suckle. Based on autopsy, causes of mortality were divided into stillborn, bitten to death, starvation, crushed, disease, and other causes. Potential risk factors of dying were estimated using a GLM with a logit link function. No significant effect (NS) of housing was observed on the odds of a piglet being stillborn (F(1,73) = 0.1, NS), being crushed (F(1,53) = 1.4, NS), or dying of starvation (F(1,53) = 0.3, NS). No significant differences were observed between the 2 genetic groups for any category of mortality. Piglet traits for pre- and postnatal survival were the same for CT and PN. The odds of being stillborn were increased in piglets born late in the birth order (F(1,1061) = 33.5, P piglets, the greater were the odds of being crushed (F(1,1050) = 18, P crushed (F(1,1050) = 4.6, P = 0.03), starving (F(1,1050) = 16.6, P crushing, starvation, and disease. Neither housing nor breeding value influenced mortality or traits of importance for the inborn viability of piglets. The results emphasize that the microclimate in the PN for newborn piglets and its heat-preserving properties are more important for survival than whether the sow is crated or penned. PMID:21148785