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Sample records for breaks treating adolescents

  1. Treating Children and Adolescents

    Science.gov (United States)

    ... Children and Adolescents Go Back Treating Children and Adolescents Email Print + Share For the most part, the ... tailored, based upon the child's weight. Children and adolescents are moving through a period of physical and ...

  2. Treating Children and Adolescents

    Science.gov (United States)

    ... Children and Adolescents Go Back Treating Children and Adolescents Email Print + Share For the most part, the ... side effects. Side effects from sulfasalazine may include headache, sun sensitivity rash, or other signs of sulfa ...

  3. Treating Depression and Oppositional Behavior in Adolescents

    Science.gov (United States)

    Jacobs, Rachel H.; Becker-Weidman, Emily G.; Reinecke, Mark A.; Jordan, Neil; Silva, Susan G.; Rohde, Paul; March, John S.

    2010-01-01

    Adolescents with depression and high levels of oppositionality often are particularly difficult to treat. Few studies, however, have examined treatment outcomes among youth with both externalizing and internalizing problems. This study examines the effect of fluoxetine, cognitive behavior therapy (CBT), the combination of fluoxetine and CBT, and…

  4. Preventing and Treating Substance Abuse among Adolescents

    Science.gov (United States)

    Sussman, Steve

    2011-01-01

    Substance misuse is one of the most prevalent causes of adolescent injury and death. Additionally, 5-8% of adolescents in the U.S. qualify for a diagnosis of substance abuse disorder. This article discusses formal prevention and treatment program models, focusing on a continuum of care which extends from prevention to treatment alternatives.…

  5. Tobacco control for clinicians who treat adolescents.

    Science.gov (United States)

    Sargent, James D; DiFranza, Joseph R

    2003-01-01

    Smoking remains the most common preventable cause of death in the developed world, and is rapidly becoming an important cause of death in the developing world. Nicotine is a powerfully addictive substance, and the tobacco industry spends billions annually promoting it in the United States. It is therefore important for clinicians to understand why people smoke, to address smoking in patients of all ages, and to lobby for health-preserving tobacco control policies at the community level. Children take up smoking in response to social influences: smoking by friends, parents, and family, and through exposure to smoking in media. Parents who smoke not only model the behavior, but also often make the product available by leaving cigarettes around the house. Media influences include the dollar 10 billion spent per year on tobacco marketing, but more importantly, the modeling of the behavior on screen by movie and television stars. Once children start smoking, many rapidly lose autonomy over the behavior. Youth can get hooked after smoking just a few cigarettes. The most effective community efforts for reducing tobacco use are: raising the price of tobacco; halting the sale of tobacco to minors; enforcing strict school tobacco policies; and making public places smoke free through local ordinances. Working with individuals, clinicians should support cessation in all smokers, including parents of children and adolescents. They should screen children for smoking risk factors beginning at age 10. They should teach parents to maintain smoke-free households, to set nonsmoking expectations early on, and to monitor adolescents for signs of smoking. Parents should limit exposure to adult media (e.g., R-rated movies) and use family television time to discuss the effect of seeing screen depictions of smoking on adolescent behavior. Adolescents who smoke should be assessed for signs of nicotine dependence and counseled about quitting. Clinicians are effective community voices; they

  6. Adolescent Catatonia Successfully Treated with Lorazepam and Aripiprazole

    Directory of Open Access Journals (Sweden)

    Aaron J. Roberto

    2014-01-01

    Full Text Available Catatonia is especially concerning in children and adolescents. It leads to significant impairment, including emotional distress, difficulty communicating, and other debilitating symptoms. In this case report, we discuss a patient with no previous history of neuroleptic medication or psychotic symptoms, presenting with first-episode catatonia in the presence of disorganized, psychotic thoughts. We then review the catatonia syndrome, citing examples in the literature supporting its underdiagnosis in children and adolescents, and discuss successful treatment modalities. It is important to diagnose and treat catatonia as efficiently as possible, to limit functional and emotional distress to the patient.

  7. Child personality facets and overreactive parenting as predictors of aggression and rule-breaking trajectories from childhood to adolescence

    OpenAIRE

    Becht, Andrik I.; Prinzie, Peter; Dekovic, Maja; Van Den Akker, Alithe L.; Rebecca L. Shiner

    2016-01-01

    This study examined trajectories of aggression and rule breaking during the transition from childhood to adolescence (ages 9–15), and determined whether these trajectories were predicted by lower order personality facets, overreactive parenting, and their interaction. At three time points separated by 2-year intervals, mothers and fathers reported on their children's aggression and rule breaking (N = 290, M age = 8.8 years at Time 1). At Time 1, parents reported on their children's personalit...

  8. Effectiveness of amitriptyline for treating functional dyspepsia in adolescents

    Directory of Open Access Journals (Sweden)

    Indra Mustawa

    2017-01-01

    Full Text Available Background Functional dyspepsia is common among adolescents. Pain reduces children’s quality of life, psychosocial functioning, and school attendance. Amitriptyline is assumed to be one of the alternative treatments in functional dyspepsia. Objective To investigate the effectiveness of amytriptyline as a treatment  for  functional dyspepsia in adolescents. Methods We conducted a randomized, single-blind, controlled trial from January to March 2011 in junior and senior high school students in Dobo City, Aru Island District, Maluku Province. Adolescents suffering from functional dyspepsia and who fulfilled the inclusion criteria were eligible for the study. Subjects were randomized into two groups. Each group received 10 mg (for body weight < 35 kg or 20 mg (for body weight ≥ 35 kg amitriptyline or placebo once per day for 28 days. Pain frequency was measured in terms of abdominal pain episodes per month, and duration was measured in minutes. Data were analyzed using t-test. Results Eighty-eight students participated in this study: the amitriptyline group (43 subjects and the placebo group (45 subjects. There were no statistically significant differences between the amitriptyline and placebo groups in frequency (P=0.777; 95%CI -0.846 to 1.129 or duration (P=0.728 of abdominal pain after treatment. Conclusion  Amitriptyline is not more effective than placebo for treating functional dyspepsia in adolescents.

  9. Child personality facets and overreactive parenting as predictors of aggression and rule-breaking trajectories from childhood to adolescence.

    Science.gov (United States)

    Becht, Andrik I; Prinzie, Peter; Deković, Maja; van den Akker, Alithe L; Shiner, Rebecca L

    2016-05-01

    This study examined trajectories of aggression and rule breaking during the transition from childhood to adolescence (ages 9-15), and determined whether these trajectories were predicted by lower order personality facets, overreactive parenting, and their interaction. At three time points separated by 2-year intervals, mothers and fathers reported on their children's aggression and rule breaking (N = 290, M age = 8.8 years at Time 1). At Time 1, parents reported on their children's personality traits and their own overreactivity. Growth mixture modeling identified three aggression trajectories (low decreasing, high decreasing, and high increasing) and two rule-breaking trajectories (low and high). Lower optimism and compliance and higher energy predicted trajectories for both aggression and rule breaking, whereas higher expressiveness and irritability and lower orderliness and perseverance were unique risk factors for increasing aggression into adolescence. Lower concentration was a unique risk factor for increasing rule breaking. Parental overreactivity predicted higher trajectories of aggression but not rule breaking. Only two Trait × Overreactivity interactions were found. Our results indicate that personality facets could differentiate children at risk for different developmental trajectories of aggression and rule breaking.

  10. Child personality facets and overreactive parenting as predictors of aggression and rule-breaking trajectories from childhood to adolescence

    NARCIS (Netherlands)

    Becht, Andrik I.; Prinzie, Peter; Dekovic, Maja; van den Akker, Alithe L.; Shiner, Rebecca L.

    2016-01-01

    This study examined trajectories of aggression and rule breaking during the transition from childhood to adolescence (ages 9–15), and determined whether these trajectories were predicted by lower order personality facets, overreactive parenting, and their interaction. At three time points separated

  11. Child personality facets and overreactive parenting as predictors of aggression and rule-breaking trajectories from childhood to adolescence

    NARCIS (Netherlands)

    Becht, A.I.; Prinzie, P.; Deković, M.; van den Akker, A.L.; Shiner, R.L.

    2016-01-01

    This study examined trajectories of aggression and rule breaking during the transition from childhood to adolescence (ages 9-15), and determined whether these trajectories were predicted by lower order personality facets, overreactive parenting, and their interaction. At three time points separated

  12. Teacher-student relationships and adolescent behavioral engagement and rule-breaking behavior: The moderating role of dopaminergic genes.

    Science.gov (United States)

    De Laet, Steven; Colpin, Hilde; Van Leeuwen, Karla; Van den Noortgate, Wim; Claes, Stephan; Janssens, Annelies; Goossens, Luc; Verschueren, Karine

    2016-06-01

    This study examined whether the dopamine transporter DAT1 and the dopamine receptor DRD4 genes moderate the effect of student-reported teacher-student relationship affiliation or dissatisfaction on parent-reported adolescent rule-breaking behavior and behavioral engagement. The sample included 1053 adolescents (51% boys, Mage=13.79) from grades 7 to 9. Regression analyses were conducted using Mplus while controlling for multiple testing and nested data. Adolescents who experienced stronger affiliation with their teachers were more engaged in school, whereas greater dissatisfaction predicted more rule-breaking behavior. In addition, a significant gene-environment interaction was found for both genes examined. The link between low teacher-student affiliation and low engagement was more pronounced for DAT1-10R homozygotes. The link between high teacher-student dissatisfaction and more rule-breaking was stronger for DRD4 non-long carriers. Implications for understanding the role of teacher-student relationships in adolescence and suggestions for future research are outlined.

  13. Comorbid psychopathology in adolescents and young adults treated for substance use disorders: a review.

    NARCIS (Netherlands)

    Couwenbergh, C.; Brink, W. van den; Zwart, K.P.; Vreugdenhil, C.; Wijngaarden-Cremers, P. van; Gaag, R.J. van der

    2006-01-01

    OBJECTIVE: In a recent review, the prevalence of comorbid psychiatric disorders in non-treated adolescents and young adults with substance use disorders (SUD) in the general population was summarized. This review looks into the prevalence of psychiatric comorbidity in adolescents and young adults tr

  14. Behavioral Problems in Children and Adolescents with Difficult-To-Treat Asthma

    NARCIS (Netherlands)

    Verkleij, Marieke; van de Griendt, Erik-Jonas; Kaptein, Ad A.; van Essen-Zandvliet, Liesbeth; Duiverman, Eric; Geenen, Rinie

    2011-01-01

    Background. The aim of this study was to quantify behavioral problems in clinically treated children and adolescents with asthma and to examine the association of these problems and quality of life with difficult-to-treat asthma. Methods. Clinical patients with difficult-to-treat asthma (n = 31) and

  15. Transactional Links Between Teacher-Student Relationships and Adolescent Rule-Breaking Behavior and Behavioral School Engagement: Moderating Role of a Dopaminergic Genetic Profile Score.

    Science.gov (United States)

    De Laet, Steven; Colpin, Hilde; Van Leeuwen, Karla; Van den Noortgate, Wim; Claes, Stephan; Janssens, Annelies; Goossens, Luc; Verschueren, Karine

    2016-06-01

    Throughout adolescence, there is an increase in rule-breaking behavior and a decrease in behavioral school engagement. The role of teacher-student relationship quality in the development of these adjustment problems remains understudied. This study examined how adolescent-reported teacher-student affiliation and dissatisfaction and parent-reported rule-breaking behavior and behavioral engagement impact one another throughout adolescence. In addition, we examined the moderating effect of genes by means of a Biologically Informed Multilocus genetic Profile Score (BIMPS), a composite score reflecting the cumulative effect of multiple dopaminergic genes, with a higher score indicating higher dopamine signaling in the adolescent brain. We used three-year longitudinal data from 1111 adolescents (51 % boys; M age = 13.79), and their parents. Cross-lagged analyses revealed a transactional process in which adolescents who display more rule-breaking behavior and less behavioral engagement experienced increased subsequent dissatisfaction with their teachers, which in turn further increased their adjustment problems. Also, adolescents with more adjustment problems experienced decreased subsequent affiliation with their teachers. The other way around, adolescents' behavioral engagement also benefitted from positive relationships with teachers. Multi-group analyses revealed genetic moderation for behavioral engagement, but not for rule-breaking. Specifically, adolescents who had a BIMPS score coding for moderate levels of dopamine signaling (instead of high or low signaling) were most affected in their behavioral engagement when they experienced dissatisfaction with their teachers. Our study findings may guide schools in implementing interventions to create a supportive class and school environment including positive, supportive teacher-student relationships and indicate that providing a such a supportive school environment is important for all adolescents.

  16. Personal Values and Moral Disengagement Promote Aggressive and Rule-Breaking Behaviours in Adolescents With Disruptive Behaviour Disorders: A Pilot Study.

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    Paciello, Marinella; Muratori, Pietro; Ruglioni, Laura; Milone, Annarita; Buonanno, Carlo; Capo, Rosario; Lochman, John E; Barcaccia, Barbara

    2017-01-01

    The pilot study presented in this article investigated the role of moral-cognitive features in understanding aggressive and rule-breaking behaviours in adolescents with Disruptive Behaviour Disorder (DBD). We collected two samples. The community sample was composed of 85 adolescents, whereas the DBD sample was composed of 30 adolescents. Compared with a community sample, adolescents with DBD are more inclined to use moral disengagement (MD) to legitimize their aggressive and rule-breaking behaviours. Moreover, regression models showed that self-enhancement values and MD foster externalizing behaviours taking into account both gender and the group they belonged to, that is, either clinical or community sample. Instead, self-transcendence values could prevent externalizing problems by inhibiting MD. Implications of these findings for assessment and therapeutic interventions are discussed.

  17. Adverse events in children and adolescents treated with quetiapine

    DEFF Research Database (Denmark)

    Jakobsen, Klaus D; Wallach-Kildemoes, Helle; Bruhn, Christina H

    2017-01-01

    Quetiapine is a low-affinity dopamine D2 receptor antagonist, approved for the treatment of bipolar disorder and schizophrenia in children and adolescents by the Food and Drug Administration, but not by European Medicine Agency. Although knowledge of adverse drug reactions in children and adolesc......Quetiapine is a low-affinity dopamine D2 receptor antagonist, approved for the treatment of bipolar disorder and schizophrenia in children and adolescents by the Food and Drug Administration, but not by European Medicine Agency. Although knowledge of adverse drug reactions in children...... 10–17 years) and six patients were boys. The main reported ADEs were (i) endocrine, for example, hyperprolactinemia and hyperthyroidism, (ii) cardiac, for example, tachycardia and QT prolongation, (iii) neurological, for example, seizures and cerebral hemorrhage, and (iv) psychiatric, for example...

  18. DNA breaks induced by micromolar concentrations of dimethylnitrosamine in liver primary cell cultures from untreated and phenobarbital treated rats.

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    Mendoza-Figueroa, T; López-Revilla, R; Villa-Treviño, S

    1983-05-01

    Direct genotoxic effects of the alkylating agent dimethylnitrosamine (DMN) have been difficult to detect in several short-term tests. We simplified our method to detect DNA breaks induced by DMN in rat liver primary cell cultures, and increased its sensitivity about 150 times by changing the conditions of ultracentrifugation and exposure to DMN. Additionally we increased 4 times the sensitivity of the improved assay by isolating hepatocytes from rats treated with phenobarbital (PB). Treatment for 24 h with 60 microM and 13.5 microM DMN of hepatocytes isolated from untreated and PB-treated rats, respectively, decreased the molecular weight of DNA by 50%. After 24 h exposure to 13.5 microM [14C]DMN, hepatocytes from PB-treated rats incorporated 3 times more radioactivity into trichloroacetic acid precipitable material than hepatocytes from untreated rats. Also PB-treatment increased remarkably cytotoxic effects of DMN while it did not modify the cytotoxicity nor the genotoxicity of the direct-acting alkylating agent N-methyl-N'-nitro-N-nitrosoguanidine. These results show that DMN is more genotoxic for hepatocytes from PB-treated rats, and suggest that the enhanced genotoxicity is probably due to an augmented metabolism of DMN by these cultures. Our improved assay of DNA breaks as an indicator of DMN genotoxicity is now as sensitive but faster to perform than hepatocyte-mediated mutagenesis. It could be used to explore genotoxic effects of other alkylating agents and the action of microsomal enzyme modifiers on genotoxicity.

  19. Adolescent Catatonia Successfully Treated with Lorazepam and Aripiprazole

    OpenAIRE

    Roberto, Aaron J.; Subhash Pinnaka; Abhishek Mohan; Hiejin Yoon; Kyle A. B. Lapidus

    2014-01-01

    Catatonia is especially concerning in children and adolescents. It leads to significant impairment, including emotional distress, difficulty communicating, and other debilitating symptoms. In this case report, we discuss a patient with no previous history of neuroleptic medication or psychotic symptoms, presenting with first-episode catatonia in the presence of disorganized, psychotic thoughts. We then review the catatonia syndrome, citing examples in the literature supporting its underdiagno...

  20. Breaking the Taboo: Illicit Drug Use among Adolescents with Type 1 Diabetes Mellitus

    Directory of Open Access Journals (Sweden)

    Anna M. Hogendorf

    2016-01-01

    Full Text Available Background. The aim of the study was to explore the prevalence of illicit drug use in a group of Polish adolescents with type 1 diabetes (DM1 in comparison with a national cohort of their healthy peers. Methods. Two hundred and nine adolescents with DM1, aged 15–18 years, were studied in 2013 with an anonymous questionnaire prepared for the European School Survey Project on Alcohol and Other Drugs (ESPAD. The control group was a representative sample of 12114 students at the same age who took part in ESPAD in 2011. Metabolic control was regarded as good if self-reported HbA1c was <8% or poor if HbA1c was ≥8%. Results. Lifetime prevalence of illicit drug use was lower among adolescents with DM1 than in the control group [58 (28% versus 5524 (46%, p=10-5]. Cannabis preparations were the most frequently used substances [38 (18.3% versus 3976 (33.1%, p=10-5], followed by tranquilizers, sedatives, and amphetamine. Lifetime and last 12-month use of cannabis were associated with poorer glycemic control (HbA1c ≥ 8%, p<0.01 and 0.02, respectively. Conclusions. Adolescents with DM1 report using illicit drugs to a lesser extent than their healthy peers. The use of cannabis is associated with a poorer metabolic control in teens with DM1.

  1. Family Characteristics, Custody Arrangements, and Adolescent Psychological Well-Being after Lesbian Mothers Break up

    Science.gov (United States)

    Gartrell, Nanette; Bos, Henny; Peyser, Heidi; Deck, Amalia; Rodas, Carla

    2011-01-01

    As part of the largest, longest running prospective American study of same-sex parent families, the present investigation examined relationship dissolution in planned lesbian families. Data were collected from 40 separated couples and their 17-year-old adolescent offspring--19 girls and 21 boys. Nearly all breakups occurred before the former…

  2. Breaking the Silence: Sharing the Japanese American Internment Experience with Adolescent Readers.

    Science.gov (United States)

    Harada, Violet H.

    1996-01-01

    Discusses 26 books that can help promote inquiry and discussion among adolescent readers regarding the internment of Japanese Americans during World War II. Notes that the books provide a historical overview and reveal personal points of view about the internment. (SR)

  3. Family characteristics, custody arrangements, and adolescent psychological well-being after lesbian mothers break up

    NARCIS (Netherlands)

    Gartrell, N.; Bos, H.; Peyser, H.; Deck, A.; Rodas, C.

    2011-01-01

    As part of the largest, longest running prospective American study of same-sex parent families, the present investigation examined relationship dissolution in planned lesbian families. Data were collected from 40 separated couples and their 17-year-old adolescent offspring—19 girls and 21 boys. Near

  4. Integrating the therapeutic into the developmental in treating disturbed adolescents.

    Science.gov (United States)

    Bloch, H Spencer

    2012-01-01

    This clinical study is organized around the treatment of a late adolescent who feared suiciding impulsively during an immobilizing depression and who proceeded to develop other severe symptoms. Yet he steadfastly refused to take medication and objected to seeing a therapist as well. His reason was an overriding wish to deal with his difficulties himself, a feature of his normal developmental imperative to emancipate to a young-adult level of psychological autonomy. Thus, the therapeutic task was to simultaneously hold him in treatment while supporting that normal developmental requisite. Elaborating upon this integration of the psychodynamic and the developmental is the major purpose of this study.

  5. Treating child and adolescent anxiety effectively: Overview of systematic reviews.

    Science.gov (United States)

    Bennett, Kathryn; Manassis, Katharina; Duda, Stephanie; Bagnell, Alexa; Bernstein, Gail A; Garland, E Jane; Miller, Lynn D; Newton, Amanda; Thabane, Lehana; Wilansky, Pamela

    2016-12-01

    We conducted an overview of systematic reviews about child and adolescent anxiety treatment options (psychosocial; medication; combination; web/computer-based treatment) to support evidence informed decision-making. Three questions were addressed: (i) Is the treatment more effective than passive controls? (ii) Is there evidence that the treatment is superior to or non-inferior to (i.e., as good as) active controls? (iii) What is the quality of evidence for the treatment? Pre-specified inclusion criteria identified high quality systematic reviews (2000-2015) reporting treatment effects on anxiety diagnosis and symptom severity. Evidence quality (EQ) was rated using Oxford evidence levels [EQ1 (highest); EQ5 (lowest)]. Twenty-two of 39 eligible reviews were high quality (AMSTAR score≥3/5). CBT (individual or group, with or without parents) was more effective than passive controls (EQ1). CBT effects compared to active controls were mixed (EQ1). SSRI/SNRI were more effective than placebo (EQ1) but comparative effectiveness remains uncertain. EQ for combination therapy could not be determined. RCTs of web/computer-based interventions showed mixed results (EQ1). CBM/ABM was not more efficacious than active controls (EQ1). No other interventions could be rated. High quality RCTs support treatment with CBT and medication. Findings for combination and web/computer-based treatment are encouraging but further RCTs are required. Head-to-head comparisons of active treatment options are needed.

  6. Vitamin D in Health and Disease in Adolescents: When to Screen, Whom to Treat, and How to Treat.

    Science.gov (United States)

    Golden, Neville H; Carey, Dennis E

    2016-01-01

    The existing guidelines on screening and treatment are confusing because different guidelines target different populations. The IOM and AAP guidelines target generally healthy populations, whereas the Endocrine Society and other subspecialty guidelines target individuals with specific medical conditions associated with increased bone fragility. These distinctions have not always been well articulated. For healthy adolescents, the AAP does not recommend universal screening or screening of obese or dark-skinned individuals. Increased dietary intake of vitamin D is recommended, and vitamin D supplementation can be considered if the RDA cannot be met. For adolescents with chronic medical illnesses associated with increased fracture risk, screening for vitamin D deficiency should be performed by obtaining a serum 25-OHD level. Those found to be deficient (25-OHD level vitamin D2 or vitamin D3 higher than the daily requirement (as discussed in the section on vitamin D and chronic disease), followed by a maintenance dose. A repeat 25-OHD level should be obtained after the therapeutic course is completed. Some experts advocate for achievement of 25-OHD levels greater than 30 ng/mL in conditions associated with increased bone fragility, and several pediatric subspecialty organizations have made recommendations specific to the diseases they treat. In such instances, the recommendations of the pediatric subspecialty organizations should take precedence over the AAP recommendations for adolescents with chronic illnesses associated with increased bone fragility because the AAP recommendations were primarily targeted at a healthy population.

  7. Joint trajectories for social and physical aggression as predictors of adolescent maladjustment: internalizing symptoms, rule-breaking behaviors, and borderline and narcissistic personality features.

    Science.gov (United States)

    Underwood, Marion K; Beron, Kurt J; Rosen, Lisa H

    2011-05-01

    This investigation examined the relation between developmental trajectories jointly estimated for social and physical aggression and adjustment problems at age 14. Teachers provided ratings of children's social and physical aggression in Grades 3, 4, 5, 6, and 7 for a sample of 255 children (131 girls, 21% African American, 52% European American, 21% Mexican American). Participants, parents, and teachers completed measures of the adolescent's adjustment to assess internalizing symptoms, rule-breaking behaviors, and borderline and narcissistic personality features. Results showed that membership in a high and rising trajectory group predicted rule-breaking behaviors and borderline personality features. Membership in a high desister group predicted internalizing symptoms, rule-breaking behaviors, and borderline and narcissistic personality features. The findings suggest that although low levels of social and physical aggression may not bode poorly for adjustment, individuals engaging in high levels of social and physical aggression in middle childhood may be at greatest risk for adolescent psychopathology, whether they increase or desist in their aggression through early adolescence.

  8. Aripiprazole for treating irritability in children & adolescents with autism: A systematic review

    Directory of Open Access Journals (Sweden)

    Ahmad Ghanizadeh

    2015-01-01

    Full Text Available Background & objectives: No clear therapeutic benefits of antipsychotics have been reported for the treatment of behavioural symptoms in autism. This systematic review provides an assessment of evidence for treating irritability in autism by aripiprazole. Methods: The databases of MEDLINE/PubMed and Google Scholar were searched for relevant articles about the effect of aripiprazole in children with autism. The articles were searched according to the inclusion and exclusion criteria specifed for this review. All the double-blind, controlled, randomized, clinical trials examining the efficacy of aripiprazole for treating children and adolescents with autism were included. Results: From the 93 titles identified, 26 were irrelevant and 58 were evaluated for more details. Only five articles met the inclusive criteria. The evidence from precise randomized double blind clinical trials of aripiprazole for the treatment of autism in children and adolescents was convincing enough to recommend aripiprazole. Adverse effects were not very common and were usually mild. Interpretation & conclusions: Current evidence suggests that aripiprazole is as effective and safe as risperidone for treating irritability in autism. However, further studies with larger sample size and longer duration are required.

  9. Incidence of cancer in adolescent idiopathic scoliosis patients treated 25 years previously

    DEFF Research Database (Denmark)

    Simony, Ane; Hansen, Emil Jesper; Christensen, Steen Bach;

    2016-01-01

    PURPOSE: To report the incidence of cancer in a cohort of adolescent idiopathic scoliosis (AIS) patients treated 25 years previously. METHODS: 215 consecutive AIS patients treated between 1983 and 1990 were identified and requested to return for clinical and radiographic examination. The incidence...... of cancer was determined through chart review and follow-up interviews. Using the original radiographic log file that included patient position, mAs, kV and the total number of X-rays taken, a radiation physicist calculated the total radiation dose during treatment and follow-up adjusted for BMI and sex...... radiation exposure was 0.8-1.4 mSV per examination and 2.4-5.6 mSv/year. An average of 16 radiographs were taken during the treatment period. Nine AIS patients developed cancer, mostly breast (3) and endometrial (4). The AIS patients had a relative risk of 4.8 (CI 2.3-5.8, p

  10. Nasal septum changes in adolescent patients treated with rapid maxillary expansion

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    Tehnia Aziz

    2016-02-01

    Full Text Available Objective: To analyze cone-beam computed tomography (CBCT scans to measure changes in nasal septal deviation (NSD after rapid maxillary expansion (RME treatment in adolescent patients. Methods: This retrospective study involved 33 patients presenting with moderate to severe nasal septum deviation as an incidental finding. Out of these 33 patients, 26 were treated for transverse maxillary constriction with RME and seven, who did not undergo RME treatment, were included in the study as control group. CBCT scans were taken before appliance insertion and after appliance removal. These images were analyzed to measure changes in nasal septum deviation (NSD. Analysis of variance for repeated measures (ANOVA was used. Results: No significant changes were identified in NSD regardless of the application or not of RME treatment and irrespective of the baseline deviation degree. Conclusion: This study did not provide strong evidence to suggest that RME treatment has any effect on NSD in adolescent patients; however, the results should be interpreted with caution, due to the small sample size and large variation amongst individual patient characteristics.

  11. Visual, auditory, and somatosensorial evoked potentials in early and late treated adolescents with phenylketonuria.

    Science.gov (United States)

    Leuzzi, V; Cardona, F; Antonozzi, I; Loizzo, A

    1994-11-01

    Pattern reversal visual, auditory, and somatosensorial evoked potentials were recorded in two groups of phenylketonuric (PKU) adolescents after protracted exposition to high concentrations of phenylalanine following diet discontinuation. The first group consisted of 11 early treated (before age 3 months) PKU patients (ET-PKU); the second group consisted of 11 late detected (after age 8 months), symptomatic, PKU subjects (LT-PKU). Despite the relevant lag between the two groups in mental development and neurological status, no clear-cut difference in evoked potentials could be detected. Only the wave I latency of the brainstem auditory evoked potentials (BAEPs) was significantly shorter in ET- versus LT-PKU children. The P100 latency, I-V interpeak latency (IPL), and I-III IPL seem to discriminate the less severe form of PKU (ET-PKU type 3) from the most severe forms, ET-PKU type 1 plus 2 and LT-PKU. No correlations were found between clinical, biochemical, and neurophysiological parameters. The present data suggest that evoked potentials technique is of limited sensitivity in detecting central nervous system (CNS) alterations in PKU adolescents after diet discontinuation.

  12. Adolescent Volar Barton Fracture with Open Physis treated with Volar Plating using Buttressing Principle

    Directory of Open Access Journals (Sweden)

    Shah H

    2015-07-01

    Full Text Available Objective: The objective of the study was to assess the outcome of Salter- Harris type III distal radius fracture fixed using the principle of buttressing and avoiding screw insertion through the physis. Materials and Method: Eight school going children in the age group of 11-16 years with volar Barton fractures were treated with a volar plate using the buttress principle without inserting screws in the distal fragment. Patients were evaluated over a period of 18 months. Clinical evaluation was done using the Green O’Brien criteria and radiological evaluation using the Sarmiento criteria. Results: The average union time was two months. All the patients had good to excellent functional outcome with full extension and flexion. Conclusion: Buttress plating of volar Barton fractures in the adolescent age group is an excellent technique to achieve satisfactory outcome without violation of the physis.

  13. Breaking Away to Find a Way: Poverty and School Failure in a Spanish Adolescent Life-History

    Science.gov (United States)

    Calderon-Almendros, I.

    2011-01-01

    This article is part of a biographical research study, and explores the social path that an adolescent from a marginal background in Malaga (Spain) has travelled throughout his life. The research shows a class differentiation that divides society in two: you, who control the means of production, impose your culture, and define the policy and the…

  14. Tratamento de macroprolactinoma com cabergolina em adolescente An adolescent patient with prolactinoma treated with cabergoline

    Directory of Open Access Journals (Sweden)

    Leila Warszawski

    2011-09-01

    Full Text Available OBJETIVO: Relatar um caso de macroprolactinoma diagnosticado em adolescente e tratado com cabergolina. DESCRIÇÃO DO CASO: Paciente do sexo feminino, 15 anos, iniciou quadro clínico aos dez anos, com cefaleia, obesidade e não havia apresentado menarca ao diagnóstico. A dosagem sérica inicial de prolactina foi de 2492ng/mL (valor de referência: 19-25ng/mL. A ressonância nuclear magnética de crânio evidenciou formação expansiva selar e suprasselar compatível com macroadenoma hipofisário sem compressão do quiasma óptico. Seis meses após o início do tratamento com cabergolina, houve queda significativa dos níveis séricos de prolactina para 87,7ng/mL, com redução de 76% no tamanho da lesão e melhora sintomática. COMENTÁRIOS: A ocorrência dos prolactinomas é rara na infância e na adolescência, mas o seu comportamento pode ser mais agressivo. O diagnóstico precoce e o manejo adequado do caso são importantes para um bom prognóstico.OBJECTIVE: To report a teenager with macroprolactinoma treated with cabergoline. CASE DESCRIPTION: A 15-year old female adolescent reported the onset of headaches and obesity since ten years old. At diagnosis amenorrhea was not present. The serum level of prolactin was initially 2492ng/mL (reference values: 19-25ng/mL. Magnetic resonance images of the skull revealed an expansive sellar and suprasellar pituitary macroadenoma without optical chiasmal compression. Six months after starting treatment with cabergoline, there was a significant decrease of prolactin levels to 87.7 ng/mL, with a 76% reduction in the lesion size and she reported improvement of the symptoms. COMMENTS: In childhood and adolescence, prolactinomas are rare, but when they occur the clinical course is more aggressive. Early diagnosis and proper management of the disease are important for a good prognosis.

  15. The role of the primary care provider in preventing and treating alcohol problems in adolescents

    NARCIS (Netherlands)

    Knight, [No Value

    2001-01-01

    Adolescents use alcohol more frequently and heavily than all other illicit drugs combined.(1) Given the myriad health, developmental, and social problems associated with alcohol use, it is not surprising that the American Medical Association's Guidelines for Adolescent Preventive Services recommends

  16. Comparison of Long-Term Outcomes in Adolescents with Anorexia Nervosa Treated with Family Therapy

    Science.gov (United States)

    Lock, James; Couturier, Jennifer; Agras, W. Stewart

    2006-01-01

    Objective: To describe the relative effectiveness of a short versus long course of family-based therapy (FBT) for adolescent anorexia nervosa at long-term follow-up. Method: This study used clinical and structured interviews to assess psychological and psychosocial outcomes of adolescents (ages 12-18 years at baseline) who were previously treated…

  17. Self-determined motivation towards physical activity in adolescents treated for obesity: an observational study

    Directory of Open Access Journals (Sweden)

    Theuwis Lotte

    2011-09-01

    Full Text Available Abstract Background Within the Self-Determination Theory (SDT framework, the first major study aim was to investigate the SDT tenets in an obese adolescent population by examining the factor structure of the Behavioural Regulation in Exercise Questionnaire-2 (BREQ-2 and by investigating associations between physical activity (PA and motivation in obese adolescents. The second aim was to study differences in motivation according to adolescents' educational level, since lower educated obese adolescent are a sub-risk group for lower PA levels among the obese adolescents. The third aim was to investigate whether attending a residential obesity treatment program could lead to an increase in autonomous motivation towards PA and to see if the treatment effect on motivation was different in low versus high educated youth. Methods For the first study aim, the sample comprised 177 obese adolescents at the start of a 10-month multidisciplinary residential obesity treatment program (BMI = 35.9 ± 6.0 kg/m2, 15.1 ± 1.5 years, 62% girls. A subsample of 65 adolescents (stratified by educational level were divided into low (n = 34 versus high educated (n = 31 as part of the second and third study aim. Motivation was assessed using the BREQ-2 and PA using the Flemish Physical Activity Questionnaire. Results Exploratory factor analysis showed sufficient validations with the original factor for 17 out of 19 BREQ-2 items. Significant positive correlations were found between PA and the composite score of relative autonomy (r = 0.31, p Conclusions The BREQ-2 can be used in an obese adolescent population. Higher levels of autonomous motivation towards PA were related to higher PA levels. Adolescents had increases in both autonomous and controlled forms of motivation during treatment. Special attention for lower educated adolescents during treatment is needed, as they have a lower autonomous motivation at the start of treatment and an increase in introjected

  18. Un juego de cartas durante los recreos escolares mejora los hábitos alimentarios en adolescentes A school breaks card game improves eating habits in adolescents

    Directory of Open Access Journals (Sweden)

    I. J. Pérez López

    2012-12-01

    Full Text Available Introducción: Los hábitos alimentarios de la población española son un problema cada vez más preocupante en la actualidad y, en especial, durante la adolescencia. Objetivos: Mejorar los hábitos alimentarios saludables (desayuno, ingestas de fruta y agua, consumo de refrescos, bollería-golosinas y fritos en adolescentes. Métodos: La intervención se llevó a cabo durante 3 meses, con alumnos de entre 12 y 16 años, mediante una propuesta educativa a través de un juego de cartas (construido ad hoc, denominado "Fighting for my health", y que se desarrolló en los recreos escolares. Éste se complementó con la metodología del compromiso saludable, caracterizado fundamentalmente por el trabajo colaborativo entre escuela y familia y por el fomento de la responsabilidad del alumnado hacia su salud. Se contó con 2 grupos (experimental y control, cada uno de ellos con un número total de 48 adolescentes. Resultados: Tras la puesta en práctica de la intervención se lograron mejoras significativas en 5 de los 6 hábitos trabajados (la excepción fue el consumo de fritos en el grupo experimental. Entre ellas sobresale especialmente la diferencia altamente significativa (p Introduction: Feeding habits among the Spanish population are currently an increasing and concerning problem, especially during adolescence. Objectives: To improve feeding habits (breakfast, consumption of fruit and water, soft drinks, pastries, sweets and fried food in adolescents. Methods: The intervention was conducted for 3 months in students from 12 to 16 years old, through an educational proposal based on a card game (built ad hoc called "Fighting for my health", which was developed during the school breaks. This game was supplemented with the methodology of a healthy commitment, based mainly on the cooperative work between schools and families and the promotion of the responsibility among students about their health. Two groups were included (intervention and control

  19. Treating paternal drug abuse using Learning Sobriety Together: effects on adolescents versus children.

    Science.gov (United States)

    Kelley, Michelle L; Fals-Stewart, William

    2008-01-01

    The focus of this study was whether couples-based treatment for substance abuse had comparable secondary benefits on the internalizing and externalizing behaviors of adolescent versus child siblings living in their homes. Couples took part in a couples-based treatment for substance abuse that combines Behavioral Couples Therapy and individual counseling (i.e., Learning Sobriety Together). During a 17-month assessment period, the relationship between parents' functioning (i.e., fathers' drug use as determined by percent days abstinent and parents' dyadic adjustment) as rated by mothers, fathers, and children's teachers and internalizing behavior (as rated by mothers' only) was stronger for children than their adolescent siblings, particularly in terms of children's externalizing behaviors. Interventions that reduce paternal drug use and improve couple functioning may reduce internalizing and externalizing symptoms for children in their homes; however, adolescents may need more intensive interventions to address internalizing and externalizing symptoms.

  20. Glycaemic control and prevalence of hypoglycaemic events in children and adolescents with type 1 diabetes mellitus treated with insulin analogues

    Directory of Open Access Journals (Sweden)

    Plavšić Ljiljana

    2014-01-01

    Full Text Available Background/Aim. An ideal insulin regimen for children and adolescents with type 1 diabetes mellitus (T1DM should be physiological, flexibile and predictable, protecting against hypoglycaemia. The aim of this study was to evaluate the influence of insulin analogues on glycaemic control and the occurrence of hypoglycaemic episodes in children and adolescents with T1DM. Methods. The study group consisted of 151 children and adolescents (90 boys, 61 girls treated with human insulins for at least 12 months before introducing insulin analogues. All the patients were divided into two groups: the group I consisted of 72 (47.7% patients treated with three injections of regular human insulin before meals and long-acting analogue (RHI/LA, and the group II of 79 (52.3% patients treated with a combination of rapid-acting and long-acting analogue (RA/LA. The levels of glycated hemoglobin (HbA1c and the number of hypoglycaemic episodes were assessed at the beginning of therapy with insulin analogues, and after 6 and 12 months. Results. The mean HbA1c was significantly lower in the group I (RHI/LA after 6 months (9.15% vs 8.20%, p < 0.001 and after 12 months (9.15% vs 8.13%, p < 0.001 as well as in the group II (RA/LA after 6 months (9.40% vs 8.24%, p < 0.001 and after 12 months of insulin analogues treatment (9.40% vs 8.38%, p < 0.001. The frequency of severe hypoglycaemia was significantly lower in both groups after 6 months (in the group I from 61.1% to 4.2% and in the group II from 54.4% to 1.3%, p < 0.001, and after 12 months (in the group I from 61.1% to 1.4% and in the group II from 54.4% to 1.3%, p < 0.001. Conclusion. Significantly better HbA1c values and lower risk of severe hypoglycaemia were established in children and adolescents with T1DM treated with insulin analogues.

  1. Eye movement desensitization and reprocessing for treating psychological disturbances in Taiwanese adolescents who experienced Typhoon Morakot.

    Science.gov (United States)

    Tang, Tze-Chun; Yang, Pinchen; Yen, Cheng-Fang; Liu, Tai-Ling

    2015-07-01

    In this case-control study, we aimed to assess the intervention effects of four-session eye movement desensitization and reprocessing (EMDR) on reducing the severity of disaster-related anxiety, general anxiety, and depressive symptoms in Taiwanese adolescents who experienced Typhoon Morakot. A total of 83 adolescents with posttraumatic stress disorder related to Typhoon Morakot, major depressive disorder, or current moderate or high suicide risk after experiencing Typhoon Morakot were allocated to a four-session course of EMDR (N = 41) or to treatment as usual (TAU; N = 42). A multivariate analysis of covariance was performed to examine the effects of EMDR in reducing the severity of disaster-related anxiety, general anxiety, and depressive symptoms in adolescents by using preintervention severity values as covariates. The multivariate analysis of covariance results indicated that the EMDR group exhibited significantly lower preintervention severity values of general anxiety and depression than did the TAU group. In addition, the preintervention severity value of disaster-related anxiety in the EMDR group was lower than that in the TAU group (p = 0.05). The results of this study support that EMDR could alleviate general anxiety and depressive symptoms and reduce disaster-related anxiety in adolescents experiencing major traumatic disasters.

  2. Psychopathy as predictor and moderator of Multisystemic Therapy outcomes among adolescents treated for antisocial behavior

    NARCIS (Netherlands)

    Manders, W.A.; Deković, M.; Asscher, J.J.; van der Laan, P.H.; Prins, P.J.M.

    2013-01-01

    Objective: The aim of the present study was to determine whether psychopathic traits act as a predictor and/or moderator of the effectiveness of Multisystemic Therapy (MST). Method: The sample included N = 256 adolescents (188 boys and 68 girls) referred for conduct problems, randomized to MST or Tr

  3. Treating stereotypy in adolescents diagnosed with autism by refining the tactic of "using stereotypy as reinforcement".

    Science.gov (United States)

    Potter, Jacqueline N; Hanley, Gregory P; Augustine, Matotopa; Clay, Casey J; Phelps, Meredith C

    2013-01-01

    Use of automatically reinforced stereotypy as reinforcement has been shown to be successful for increasing socially desirable behaviors in persons with intellectual disabilities (Charlop, Kurtz, & Casey, 1990; Hanley, Iwata, Thompson, & Lindberg, 2000; Hung, 1978). A component analysis of this treatment was conducted with 3 adolescents who had been diagnosed with autism, and then extended by (a) progressively increasing the quantitative and qualitative aspects of the response requirement to earn access to stereotypy, (b) arranging objective measures of client preference for contingent access to stereotypy compared to other relevant treatments for their automatically reinforced stereotypy, and (c) assessing the social validity of this treatment with other relevant stakeholders. Implications for addressing stereotypy and increasing the leisure skills of adolescents with autism are discussed.

  4. Severe hypertension due to renal polar artery stenosis in an adolescent treated with coil embolization

    Energy Technology Data Exchange (ETDEWEB)

    Docx, Martine K. [Koningin Paola Kinderziekenhuis, Department of Paediatrics, Chronic Diseases and Hypertension, Antwerp (Belgium); Vandenberghe, Philippe [Koningin Paola Kinderziekenhuis, Department of Paediatric Cardiology, Antwerp (Belgium); Maleux, Geert [University Hospitals Leuven, Department of Radiology, Leuven (Belgium); Gewillig, Marc [University Hospitals Leuven, Department of Paediatric Cardiology, Leuven (Belgium); Mertens, Luc [Hospital for Sick Children, Paediatric Cardiology, Toronto (Canada)

    2009-11-15

    A 12-year-old boy presented with severe arterial hypertension due to a severe subsegmental renal artery stenosis. Treatment consisted of selective embolization of the stenosed polar artery, which resulted in near normalization of the arterial pressures. Renal artery stenosis should always be considered, even in young adolescents, as a cause for arterial hypertension. Only selective angiography was able to demonstrate the subsegmental artery stenosis in this patient. (orig.)

  5. Dying after cure: A case of suicide in an adolescent treated for cancer

    Directory of Open Access Journals (Sweden)

    Laura Veneroni

    2015-01-01

    Full Text Available Although suicide among childhood cancer survivors is rare, there is still a significantly higher risk in this population than in healthy adolescents. A 17-year-old girl cured of Burkitt lymphoma committed suicide after completing her treatment. She had never previously shown signs of psychological suffering and was in good general health. This case made the operators wonder how this tragic possibility might be prevented. It is essential for the ongoing monitoring of the psychological and social suffering of young people during follow-up programs to be assured by a multidisciplinary team involved in the patient′s global care.

  6. Health-related quality of life of adolescents conservatively treated for idiopathic scoliosis in Korea: a cross-sectional study

    OpenAIRE

    Lee, Hyejung; Choi, Jihea; Hwang, Jin-Ho; Park, Jung Hyun

    2016-01-01

    Background Young adolescents with scoliosis are more likely than adults to experience psychological distress affecting health-related quality of life (HRQoL). Adolescence is a sensitive period of psychological development, and thus physical deformity from scoliosis can negatively affect body image and appearance of adolescents. The present study evaluated HRQoL in young Korean adolescents with idiopathic scoliosis and identified related factors. Methods One hundred and ten adolescents with id...

  7. Break It

    Institute of Scientific and Technical Information of China (English)

    MATTHEW PLOWRIGHT; GWYNN GUILFORD

    2008-01-01

    @@ Resolutions are not natural - otherwise you wouldn't have to "resolve" to execute them. This year, instead of planning how to commit to a slew of unattainable goals, why not prepare for breaking your resolutions the right way?

  8. Nutritional assessment and lipid profile in HIV-infected children and adolescents treated with highly active antiretroviral therapy

    Directory of Open Access Journals (Sweden)

    Marina Hjertquist Tremeschin

    2011-06-01

    Full Text Available INTRODUCTION: HIV-infected children and adolescents treated with highly active antiretroviral therapy (HAART regimens that include a protease inhibitor (PI can show significant improvements in clinical outcomes, nutritional status and quality of life. The study aimed to report nutritional and metabolic alterations for pediatric patients continuously exposed to HAART and for healthy controls for up to 1 year. METHODS: Clinical, anthropometric, lipid profile and food intake data were collected prospectively over approximately 12-months for each patient. RESULTS: Fifty-one individuals were studied, of these, 16 were healthy. After 12 months follow-up, HIV-positive individuals remained below the healthy control group parameters. No change was observed concerning food intake. Triglyceride serum levels were higher in patients using protease inhibitor at the onset of the study [PI groups: 114 (43 - 336, and 136 (63 - 271 versus control group: 54.5 (20 - 162; p = 0.003], but after twelve months follow-up, only the group using protease inhibitor for up to two months presented higher values [140 (73 - 273 versus 67.5 (33 - 117; p = 0.004]. HDL-cholesterol was lower in HIV-positive individuals [HIV-positive groups: 36 (27 - 58 and 36 (23 - 43; control 49.5 (34 - 69; p = 0.004]. CONCLUSIONS: HIV-infected children and adolescents treated with highly active antiretroviral therapy showed compromised nutritional parameters compared to a paired healthy control group. Individuals using protease inhibitor presented worse triglyceride serum levels compared to their healthy counterparts.

  9. Neurological, Metabolic, and Psychiatric Adverse Events in Children and Adolescents Treated With Aripiprazole

    DEFF Research Database (Denmark)

    Jakobsen, Klaus Damgaard; Bruhn, Christina Hedegaard; Pagsberg, Anne-Katrine

    2016-01-01

    with schizophrenia and psychoses, not otherwise specified; and the non-PS group consisted of fourteen cases including autism spectrum disorders, attention deficit and hyperactivity disorder, obsessive-compulsive disorder, and Tourette syndrome. The main reported adverse effects in the non-PS group were chronic......Aripiprazole is a partial dopamine agonist with only minor neurological and psychiatric adverse effects, making it a potential first-line drug for the treatment of psychiatric disorders. However, the evidence of its use in children and adolescents is rather sparse. The aim of this case study...... [aripiprazole] AND all spontaneous reports since the introduction of aripiprazole in 2003 until December 31, 2015. Nineteen case reports were included in the study and included both patients with psychotic disorders (PS group) and nonpsychotic disorders (non-PS group). The PS group consisted of 5 patients...

  10. Aripiprazole versus risperidone for treating children and adolescents with tic disorder: a randomized double blind clinical trial.

    Science.gov (United States)

    Ghanizadeh, Ahmad; Haghighi, Alireza

    2014-10-01

    There are some uncontrolled studies about the efficacy and safety of both aripiprazole and risperidone for treating tic disorder. Moreover, the efficacy of these medications has never been compared. This is the first double blind randomized clinical trial comparing the safety and efficacy of aripiprazole and risperidone for treating patients with tic disorder. Sixty children and adolescents with tic disorder were randomly allocated into one of the two groups to receive either aripiprazole or risperidone for 2 months. The primary outcome measure was the score of Yale Global Tic Severity Scale. In addition, health related quality of life and adverse events were assessed. Both aripiprazole and risperidone decreased the Yale Global Tic Severity Scale score during this trial. Moreover, both medications increased the health related quality of life score. Both aripiprazole and risperidone were tolerated well. Aripiprazole [3.22 (1.9) mg/day] decreased tic score as much as risperidone [0.6 (0.2) mg/day]. Their adverse effects and their effects on health related quality of life were comparable. However, risperidone increased the patients' social functioning more than aripiprazole in short term.

  11. Adolescent Spasmodic Torticollis Treated by Moxibustion——A Report on 30 Cases

    Institute of Scientific and Technical Information of China (English)

    Zhou Liwu

    2007-01-01

    @@ Spasmodic torticollis is characterized by involuntary contraction of the cervical muscles and the patient will have uni-directional paroxysmal vibration of the neck. The author has treated the disease by applying moxibustion and achieved quite satisfactory therapeutic effects. A report follows.

  12. Renal function in HIV-infected children and adolescents treated with tenofovir disoproxil fumarate and protease inhibitors

    Directory of Open Access Journals (Sweden)

    Pontrelli Giuseppe

    2012-01-01

    Full Text Available Abstract Background Kidney disease is an important complication in HIV infected people, and this may be related to infection or antiretroviral therapy (ART. Our aim is to assess renal function in HIV infected paediatric patients, who may be particularly affected and are likely to take ART for longer than adults, and investigate the long term role of Tenofovir Disoproxil Fumarate (TDF alone or co-administered with Ritonavir-boosted Protease Inhibitors (PI. Methods Serum creatinine, phosphate and potassium levels, with estimated Glomerular Filtration Rate (eGFR, had been prospectively evaluated for 2 years in a cohort of HIV infected children and adolescents (age 9-18 on ART, and data analyzed according to the exposure to TDF or simultaneous TDF and PI. Results Forty-nine patients were studied (57% female, mean age 14. Sixty-three percent were treated with ART containing TDF (Group A, and 37% without TDF (Group B; 47% with concomitant use of TDF and PI (Group C and 53% without this combination (Group D. The groups didn't differ for age, gender or ethnicity. The median creatinine increased in the entire cohort and in all the groups analyzed; eGFR decreased from 143.6 mL/min/1.73 m2 at baseline to 128.9 after 2 years (p = 0.006 in the entire cohort. Three patients presented a mild eGFR reduction, all were on TDF+PI. Phosphatemia decreased significantly in the entire cohort (p = 0.0003 and in TDF+PI group (p = 0.0128 after 2 years. Five patients (10% developed hypophosphatemia (Division of Acquired Immune Deficiency AE grade 1 or 2, and four of them were on TDF+PI. Conclusions Renal function decrease and hypophosphatemia occur over time in HIV infected children and adolescents on ART. The association with co-administration of TDF and PI appears weak, and further studies are warranted.

  13. The Break

    DEFF Research Database (Denmark)

    Strand, Anete Mikkala Camille

    2016-01-01

    The chapter elaborates on how to deal with one of the major challenges facing organizations worldwide; Stress. The Break enacts a quantum approach to meet the challenges by proposing a combination of three different quantum storytelling technologies; protreptic mentoring, walking and material sto...

  14. Breaking Routines

    DEFF Research Database (Denmark)

    Kesting, Peter; Jørgensen, Frances

    2010-01-01

    On some level, innovation begins when the current way of doing things is questioned and alternatives are sought. In cognitive terms, this can be conceptualized as the point at which an agent breaks with existing routine and returns to planning and decision-making. Thus far, however, very little...

  15. Supersymmetry breaking

    Indian Academy of Sciences (India)

    Emilian Dudas

    2009-01-01

    We review the various mechanisms of supersymmetry breaking and its trans-mission to the observable sector. We argue that hybrid models where gauge dominates over gravity mediation, but gravity provides the main contributions to the Higgs sector masses and the neutralino mass, are able to combine the advantages and reduce the disadvantages of the two transmission mechanisms.

  16. Aripiprazole for treating irritability in children & adolescents with autism: A systematic review

    OpenAIRE

    Ahmad Ghanizadeh; Sylvie Tordjman; Nematollah Jaafari

    2015-01-01

    Background & objectives: No clear therapeutic benefits of antipsychotics have been reported for the treatment of behavioural symptoms in autism. This systematic review provides an assessment of evidence for treating irritability in autism by aripiprazole. Methods: The databases of MEDLINE/PubMed and Google Scholar were searched for relevant articles about the effect of aripiprazole in children with autism. The articles were searched according to the inclusion and exclusion criteria speci...

  17. The epidemiology of pharmacologically treated attention deficit hyperactivity disorder (ADHD) in children, adolescents and adults in UK primary care

    LENUS (Irish Health Repository)

    McCarthy, Suzanne

    2012-06-19

    AbstractBackgroundAttention Deficit Hyperactivity Disorder (ADHD) is a common neurodevelopmental disorder characterised by the symptoms of inattention, impulsivity and hyperactivity. ADHD was once perceived as a condition of childhood only; however increasing evidence has highlighted the existence of ADHD in older adolescents and adults. Estimates for the prevalence of ADHD in adults range from 2.5–4%. Few data exist on the prescribing trends of the stimulants methylphenidate and dexamfetamine, and the non-stimulant atomoxetine in the UK. The aim of this study was to investigate the annual prevalence and incidence of pharmacologically treated ADHD in children, adolescents and adults in UK primary care.MethodsThe Health Improvement Network (THIN) database was used to identify all patients aged over 6 years with a diagnosis of ADHD\\/hyperkinetic disorder and a prescription for methylphenidate, dexamfetamine or atomoxetine from 2003–2008. Annual prevalence and incidence of pharmacologically treated ADHD were calculated by age category and sex.ResultsThe source population comprised 3,529,615 patients (48.9% male). A total of 118,929 prescriptions were recorded for the 4,530 patients in the pharmacologically treated ADHD cohort during the 6-year study. Prevalence (per 1000 persons in the mid-year THIN population) increased within each age category from 2003 to 2008 [6–12 years: from 4.8 (95% CI: 4.5–5.1) to 9.2 (95% CI: 8.8–9.6); 13–17 years: from 3.6 (95% CI: 3.3–3.9) to 7.4 (95% CI: 7.0–7.8); 18–24 years: from 0.3 (95% CI: 0.2–0.3) to 1.1 (95% CI: 1.0–1.3); 25–45 years: from 0.02 (95% CI: 0.01–0.03) to 0.08 (95% CI: 0.06–0.10); >45 years: from 0.01 (95% CI: 0.00–0.01) to 0.02 (95% CI: 0.01–0.03). Whilst male patients aged 6-12 years had the highest prevalence; the relative increase in prescribing was higher amongst female patients of the same age - the increase in prevalence in females aged 6–12 years was 2.1 fold

  18. The epidemiology of pharmacologically treated attention deficit hyperactivity disorder (ADHD in children, adolescents and adults in UK primary care

    Directory of Open Access Journals (Sweden)

    McCarthy Suzanne

    2012-06-01

    Full Text Available Abstract Background Attention Deficit Hyperactivity Disorder (ADHD is a common neurodevelopmental disorder characterised by the symptoms of inattention, impulsivity and hyperactivity. ADHD was once perceived as a condition of childhood only; however increasing evidence has highlighted the existence of ADHD in older adolescents and adults. Estimates for the prevalence of ADHD in adults range from 2.5–4%. Few data exist on the prescribing trends of the stimulants methylphenidate and dexamfetamine, and the non-stimulant atomoxetine in the UK. The aim of this study was to investigate the annual prevalence and incidence of pharmacologically treated ADHD in children, adolescents and adults in UK primary care. Methods The Health Improvement Network (THIN database was used to identify all patients aged over 6 years with a diagnosis of ADHD/hyperkinetic disorder and a prescription for methylphenidate, dexamfetamine or atomoxetine from 2003–2008. Annual prevalence and incidence of pharmacologically treated ADHD were calculated by age category and sex. Results The source population comprised 3,529,615 patients (48.9% male. A total of 118,929 prescriptions were recorded for the 4,530 patients in the pharmacologically treated ADHD cohort during the 6-year study. Prevalence (per 1000 persons in the mid-year THIN population increased within each age category from 2003 to 2008 [6–12 years: from 4.8 (95% CI: 4.5–5.1 to 9.2 (95% CI: 8.8–9.6; 13–17 years: from 3.6 (95% CI: 3.3–3.9 to 7.4 (95% CI: 7.0–7.8; 18–24 years: from 0.3 (95% CI: 0.2–0.3 to 1.1 (95% CI: 1.0–1.3; 25–45 years: from 0.02 (95% CI: 0.01–0.03 to 0.08 (95% CI: 0.06–0.10; >45 years: from 0.01 (95% CI: 0.00–0.01 to 0.02 (95% CI: 0.01–0.03. Whilst male patients aged 6-12 years had the highest prevalence; the relative increase in prescribing was higher amongst female patients of the same age - the increase in prevalence in females aged 6–12 years was 2

  19. Quality of life in Danish children and adolescents with type 1 diabetes treated with continuous subcutaneous insulin infusion or multiple daily injections

    DEFF Research Database (Denmark)

    Birkebæk, Niels; Kristensen, Lene Juel; Mose, Anne;

    2014-01-01

    for more than one year) and 405 with MDI (238 for more than one year). Participants and their parents completed the Pediatric Quality of Life Inventory Diabetes and Generic Module. HbA1c was analyzed centrally. RESULTS: Parents reported children and adolescents on CSII for more than one year to have less......AIMS: The aims of the study were to compare health-related quality of life (HRQoL) in a National Danish population of children and adolescents with type 1 diabetes (T1D) treated with either continuous subcutaneous insulin injection (CSII) or multiple daily insulin injections (MDI...... diabetes-related symptoms and worry, less problems in communicating diabetes, and better generic functioning compared with those on MDI. Children and adolescents on CSII for more than one year reported less diabetes-related symptoms, but more treatment problems, and better generic functioning in all...

  20. Breaking Symmetries

    Directory of Open Access Journals (Sweden)

    Kirstin Peters

    2010-11-01

    Full Text Available A well-known result by Palamidessi tells us that πmix (the π-calculus with mixed choice is more expressive than πsep (its subset with only separate choice. The proof of this result argues with their different expressive power concerning leader election in symmetric networks. Later on, Gorla offered an arguably simpler proof that, instead of leader election in symmetric networks, employed the reducibility of incestual processes (mixed choices that include both enabled senders and receivers for the same channel when running two copies in parallel. In both proofs, the role of breaking (initial symmetries is more or less apparent. In this paper, we shed more light on this role by re-proving the above result - based on a proper formalization of what it means to break symmetries without referring to another layer of the distinguishing problem domain of leader election. Both Palamidessi and Gorla rephrased their results by stating that there is no uniform and reasonable encoding from πmix into πsep. We indicate how the respective proofs can be adapted and exhibit the consequences of varying notions of uniformity and reasonableness. In each case, the ability to break initial symmetries turns out to be essential.

  1. Perception of stress level, trunk appearance, body function and mental health in females with adolescent idiopathic scoliosis treated conservatively: a longitudinal analysis

    OpenAIRE

    Misterska, Ewa; Glowacki, Maciej; Latuszewska, Joanna; Adamczyk, Katarzyna

    2012-01-01

    Purpose In the presented study, we aimed to assess changes over time in the perception of trunk deformity, body function, stress level and mental health in females with adolescent idiopathic scoliosis (AIS) who were treated conservatively with a Cheneau brace, taking the Trunk Appearance Perception Scale (TAPS), Scoliosis Research Society-22 (SRS-22) and Bad Sobberheim Stress Questionnaires (BSSQ) criteria of evaluation into consideration. Methods The study design was comprised of three quest...

  2. Breaking Symmetries

    CERN Document Server

    Peters, Kirstin

    2010-01-01

    A well-known result by Palamidessi tells us that {\\pi}mix (the {\\pi}-calculus with mixed choice) is more expressive than {\\pi}sep (its subset with only separate choice). The proof of this result argues with their different expressive power concerning leader election in symmetric networks. Later on, Gorla of- fered an arguably simpler proof that, instead of leader election in symmetric networks, employed the reducibility of "incestual" processes (mixed choices that include both enabled senders and receivers for the same channel) when running two copies in parallel. In both proofs, the role of breaking (ini- tial) symmetries is more or less apparent. In this paper, we shed more light on this role by re-proving the above result-based on a proper formalization of what it means to break symmetries-without referring to another layer of the distinguishing problem domain of leader election. Both Palamidessi and Gorla rephrased their results by stating that there is no uniform and reason- able encoding from {\\pi}mix i...

  3. Breaking Symmetries

    CERN Document Server

    Peters, Kirstin; 10.4204/EPTCS.41.10

    2010-01-01

    A well-known result by Palamidessi tells us that \\pimix (the \\pi-calculus with mixed choice) is more expressive than \\pisep (its subset with only separate choice). The proof of this result argues with their different expressive power concerning leader election in symmetric networks. Later on, Gorla offered an arguably simpler proof that, instead of leader election in symmetric networks, employed the reducibility of incestual processes (mixed choices that include both enabled senders and receivers for the same channel) when running two copies in parallel. In both proofs, the role of breaking (initial) symmetries is more or less apparent. In this paper, we shed more light on this role by re-proving the above result - based on a proper formalization of what it means to break symmetries without referring to another layer of the distinguishing problem domain of leader election. Both Palamidessi and Gorla rephrased their results by stating that there is no uniform and reasonable encoding from \\pimix into \\pisep. We...

  4. The Break

    DEFF Research Database (Denmark)

    Strand, Anete Mikkala Camille; Larsen, Jens

    2015-01-01

    are elaborated as founding differences for the leadership actions to come aka for the engagement in practices of becoming. Material storytelling story modes are posed as material-discursive attempts at rebalancing present hegemonies of mind/body, nature/culture, matter/meaning, etc. with relation to the posed...... and euro each year. The paper tries to explore new ways to deal with these challenges through a quantum approach to storytelling where the enactment of core values, bodies, spaces and artifacts positions managers and CEO’s from major Scandinavian organizations in sites where they can re-evaluate their life...... stones on a table in an office of a municipality in Denmark. Silence….. Rebuilding rooms for taking breaks with the inclusion of different activities such as a game of soccer or a hike seems to provide the tools to rework these imbalances or enslaving patterns. Break……. The attempt at meeting...

  5. Treating adolescents with cannabis use disorder with Multidimensional Family Therapy (MDFT): Main results of a Randomized Controlled Trial (RCT)

    NARCIS (Netherlands)

    P. Tossmann (Peter); B. Jonas (Benjamin); H. Rigter (Henk); A. Gantner (Andreas)

    2012-01-01

    textabstractAims: To determine the effectiveness of Multidimensional Family Therapy (MDFT) among adolescents with cannabis use disorder in Germany. Methods: In a randomized controlled trial (RCT), MDFT was compared with Youth Psychotherapy (JUP), an individual intervention including Cognitive Behavi

  6. Cortical brain morphology in young, estrogen-naive, and adolescent, estrogen-treated girls with Turner syndrome.

    Science.gov (United States)

    Lepage, Jean-Francois; Mazaika, Paul K; Hong, David S; Raman, Mira; Reiss, Allan L

    2013-09-01

    Turner syndrome (TS) is a genetic condition that permits direct investigation of the complex interaction among genes, hormones, behavior, and brain development. Here, we used automated segmentation and surface-based morphometry to characterize the differences in brain morphology in children (n = 30) and adolescents (n = 16) with TS relative to age- and sex-matched control groups (n = 21 and 24, respectively). Our results show that individuals with TS, young and adolescent, present widespread reduction of gray matter volume, white matter volume and surface area (SA) over both parietal and occipital cortices bilaterally, as well as enlarged amygdala. In contrast to the young cohort, adolescents with TS showed significantly larger mean cortical thickness and significantly smaller total SA compared with healthy controls. Exploratory developmental analyses suggested aberrant regional brain maturation in the parahippocampal gyrus and orbitofrontal regions from childhood to adolescence in TS. These findings show the existence of abnormal brain morphology early in development in TS, but also suggest the presence of altered neurodevelopmental trajectories in some regions, which could potentially be the consequences of estrogen deficiency, both pre- and postnatally.

  7. Recognizing and treating uncommon behavioral and emotional disorders in children and adolescents who have been severely maltreated: reactive attachment disorder.

    Science.gov (United States)

    Haugaard, Jeffrey J; Hazan, Cindy

    2004-05-01

    This article explores reactive attachment disorder, a disorder that has been linked to severe and chronic maltreatment. The fundamental concepts of attachment theory are reviewed briefly, and the two types of behaviors associated with reactive attachment disorder in children and adolescents are discussed. Treatment strategies are explored, including the controversial holding or rebirthing strategies.

  8. One-year outcome and incidence of anorexia nervosa and restrictive eating disorders among adolescent girls treated as out-patients in a family-based setting.

    Science.gov (United States)

    Rosling, Agneta; Salonen Ros, Helena; Swenne, Ingemar

    2016-01-01

    Aims To study the 1-year outcome and to analyse predictors of outcome of a cohort of adolescent girls with anorexia nervosa (AN) or restrictive eating disorders not otherwise specified (EDNOSr) treated as out-patients in a family-based programme at a specialized eating disorder service. To calculate the incidence of anorexia nervosa among treatment-seeking girls younger than 18 in Uppsala County from 2004 to 2006. Methods A total of 168 female patients were offered treatment, and 141 were followed-up 1 year after starting treatment, 29 with AN and 112 with EDNOSr. Results Of the 29 girls who initially had AN, 6 (20%) had a good outcome and were free of any form of eating disorder at follow-up; only 1 (3%) had AN. Of the patients with EDNOSr, 54 (48%) had a good outcome and were free of eating disorders. Three (3%) had a poor outcome and had developed AN. The incidence of AN was 18/100,000 person-years in girls younger than 12 and 63/100,000 in girls younger than 18. Conclusion Restrictive eating disorders, including AN, in children and adolescents can be successfully treated in a family-based specialized out-patient service without in-patient care.

  9. Clinical audit on "Evaluation of special issues in adolescents with cancer treated in an adult cancer setting": An Indian experience

    Directory of Open Access Journals (Sweden)

    Naveen S Salins

    2012-01-01

    Results: Pain was the most common physical symptom seen in all 10 patients. 3 out of 10 patients were involved in decision making, 3 out of 10 patients had identity issues and 4 out of 10 patients had peer group isolation issues. Only 3 were aware of diagnosis and none were aware of treatment outcomes and mortality. 4 out of 10 had anxiety and depression and 3 out of 10 had body image issues. Sexuality, spiritual and existential issues were not explored in any of the patients studied. Conclusion: The outcomes of the study were in an adult oncology setting there was a poor recognition of key adolescent issues such as sexuality, body image, identity and peer group isolation. The psychosocial supports to these adolescents were minimal and spiritual and existential issues were not explored. The inferences drawn from this study suggested a need for multidisciplinary team approach oriented in handling adolescent care needs and preferably to have a dedicated space that will help the peer group to interact, bond and cope better with the illness.

  10. Bootstrap Dynamical Symmetry Breaking

    Directory of Open Access Journals (Sweden)

    Wei-Shu Hou

    2013-01-01

    Full Text Available Despite the emergence of a 125 GeV Higgs-like particle at the LHC, we explore the possibility of dynamical electroweak symmetry breaking by strong Yukawa coupling of very heavy new chiral quarks Q . Taking the 125 GeV object to be a dilaton with suppressed couplings, we note that the Goldstone bosons G exist as longitudinal modes V L of the weak bosons and would couple to Q with Yukawa coupling λ Q . With m Q ≳ 700  GeV from LHC, the strong λ Q ≳ 4 could lead to deeply bound Q Q ¯ states. We postulate that the leading “collapsed state,” the color-singlet (heavy isotriplet, pseudoscalar Q Q ¯ meson π 1 , is G itself, and a gap equation without Higgs is constructed. Dynamical symmetry breaking is affected via strong λ Q , generating m Q while self-consistently justifying treating G as massless in the loop, hence, “bootstrap,” Solving such a gap equation, we find that m Q should be several TeV, or λ Q ≳ 4 π , and would become much heavier if there is a light Higgs boson. For such heavy chiral quarks, we find analogy with the π − N system, by which we conjecture the possible annihilation phenomena of Q Q ¯ → n V L with high multiplicity, the search of which might be aided by Yukawa-bound Q Q ¯ resonances.

  11. Mental Health of Adults Treated in Adolescence with Scoliosis-Specific Exercise Program or Observed for Idiopathic Scoliosis

    OpenAIRE

    2014-01-01

    Objective. To examine general mental health in adult males and females, who in adolescence participated in a scoliosis-specific therapeutic exercise program or were under observation due to diagnosis of scoliosis. Design. Registry-based, cross-sectional study with retrospective data collection. Methods. Sixty-eight subjects (43 women) aged 30.10 (25–39) years, with mild or moderate scoliosis (11–36° Cobb angle), and 76 (38 women) nonscoliotic subjects, aged 30.11 (24–38) years, participated. ...

  12. Acute Myeloid Leukemia in Adolescents and Young Adults Treated in Pediatric and Adult Departments in the Nordic Countries

    DEFF Research Database (Denmark)

    Wennström, Lovisa; Edslev, Pernille Wendtland; Abrahamsson, Jonas;

    2016-01-01

    countries. RESULTS: The incidence of AML was 4.9/million/year for the age group 10-14 years, 6.5 for 15-18 years, and 6.9 for 19-30 years. Acute promyelocytic leukemia (APL) was more frequent in adults and in females of all ages. Pediatric patients with APL had similar overall survival as pediatric patients......BACKGROUND: Studies on adolescents and young adults with acute lymphoblastic leukemia suggest better results when using pediatric protocols for adult patients, while corresponding data for acute myeloid leukemia (AML) are limited. PROCEDURE: We investigated disease characteristics and outcome...

  13. Is the next generation of physicians adequately prepared to diagnose and treat eating disorders in children and adolescents?

    Science.gov (United States)

    Girz, Laura; Robinson, Adele Lafrance; Tessier, Carole

    2014-01-01

    This study examined medical residents' comfort with and knowledge of eating disorder assessment and treatment practices for children and adolescents. Since entering medical school, the majority of respondents reported receiving fewer than 5 hours of training in this area. Participants reported feeling more comfortable with the assessment of eating disorders than with their medical management and treatment. Questions testing participants' knowledge in these domains reflected this finding; participants did well on the assessment questions, but quite poorly on the treatment questions. Intensity of training and self-reported comfort with these skills predicted residents' knowledge, suggesting that additional training opportunities are warranted.

  14. Quality of life and social isolation in Greek adolescents with primary focal hyperhidrosis treated with botulinum toxin type A: a case series.

    Science.gov (United States)

    Kouris, Anargyros; Armyra, Kalliopi; Stefanaki, Christina; Christodoulou, Christos; Karimali, Polixeni; Kontochristopoulos, George

    2015-01-01

    Primary hyperhidrosis, although extensively documented in adults, typically has onset that dates back to early childhood. It is an unpleasant and socially disabling problem for the affected child, but little attention has been paid to the disease in adolescents. The objective of the current study was to evaluate the effectiveness of botulinum toxin type A (BTXA) in adolescents with primary palmar and axillary hyperhidrosis and to determine its effect on quality of life and social isolation. Thirty-five individuals (17 girls, 18 boys) with moderate to severe palmar and axillary hyperhidrosis were treated with BTXA (onabotulinum). Patients were examined at baseline and 6 months after treatment. The Hyperhidrosis Disease Severity Scale (HDSS) was used to evaluate disease severity and the Children's Dermatology Life Quality Index (CDLQI) was used to assess quality of life. The University of California at Los Angeles loneliness scale (UCLA version 3) was used to assess personal perception of loneliness and social isolation. The median age of the participants was 14 years, and 48.6% were female. Twenty-one had palmar hyperhidrosis, and 14 had axillary hyperhidrosis. Total CDLQI and social isolation scores decreased significantly after treatment with BTXA (both p hyperhidrosis. No statistically significant difference was documented for CDLQI and UCLA scores between boys and girls. Treatment of hyperhidrosis with BTXA resulted in improvement in quality of life, social skills, and activities.

  15. Long-term outcome of 25 children and adolescents with severe aplastic anemia treated with antithymocyte globulin

    Directory of Open Access Journals (Sweden)

    de-Medeiros C.R.

    2000-01-01

    Full Text Available Severe aplastic anemia (SAA is probably an immune-mediated disorder, and immunosuppressive therapy is recommended for patients with no available donor for bone marrow transplant. Between October 1984 and November 1987, 25 consecutive children and adolescents with SAA with no HLA-compatible marrow donor received equine antithymocyte globulin (ATG (15 mg kg-1 day-1 for 10 days. The patients were evaluated 6 weeks, 6 months, and 12 months after starting ATG treatment. Thereafter, patients were evaluated yearly until July 1998. Median age was 10 years (range, 1.5-20 years, granulocyte counts on referral ranged from 0.032 to 1.4 x 10(9/l (median 0.256 x 10(9/l, and 12 patients had granulocyte counts <0.2 x 10(9/l. At a median follow-up of 9.6 years (range, 8.6-11.8 years, 10 patients (40% remained alive with good marrow function. No morphologic evidence of hematological clonal disorders has been observed, although two patients probably have acquired clonal chromosomal abnormalities (trisomy 8 and del(6q21, respectively. Responses to ATG were observed between 6 weeks and 6 months from the start of treatment in 60% of evaluable patients. The response rate was not different in patients whose granulocyte count at diagnosis was <0.2 x 10(9/l, or in those who were <10 years of age. This study supports the view that, when compared with supportive measures, ATG is an effective treatment for children or adolescents with SAA. Although these results are inferior to those reported for marrow transplantation or more intensive immunosuppressive regimens, these patients who responded to ATG are long-term survivors with stable peripheral blood counts and a low rate of relapse.

  16. Epigenetic and genetic variants in the HTR1B gene and clinical improvement in children and adolescents treated with fluoxetine.

    Science.gov (United States)

    Gassó, Patricia; Rodríguez, Natalia; Blázquez, Ana; Monteagudo, Ana; Boloc, Daniel; Plana, Maria Teresa; Lafuente, Amalia; Lázaro, Luisa; Arnaiz, Joan Albert; Mas, Sergi

    2017-04-03

    The serotonin 1B receptor (5-HT1B) is important to both the pathogenesis of major depressive disorder and the antidepressant effects of selective serotonin reuptake inhibitors. Although fluoxetine has been shown to be effective and safe in children and adolescents, not all patients experience a proper clinical response, which has led to further study into the main factors involved in this inter-individual variability. Our aim was to study the effect of epigenetic and genetic factors that could affect 5-hydroxytryptamine receptor 1B (HTR1B) gene expression, and thereby response to fluoxetine. A total of 83 children and adolescents were clinically assessed 12weeks after of initiating an antidepressant treatment with fluoxetine for the first time. We evaluated the influence of single nucleotide polymorphisms (SNPs) specifically located in transcription factor binding sites (TFBSs) on their clinical improvement. A combined genetic analysis considering the significant SNPs together with the functional variant rs130058 previously associated in our population was also performed. Moreover, we assessed, for the first time in the literature, whether methylation levels of the HTR1B promoter region could be associated with the pharmacological response. Two, rs9361233 and rs9361235, were significantly associated with clinical improvement after treatment with fluoxetine. The heterozygous genotype combination analysis showed a negative correlation with clinical improvement. The lowest improvement was experienced by patients who were heterozygous for all three SNPs. Moreover, a negative correlation was found between clinical improvement and the average methylation level of the HTR1B promoter. These results give new evidence for the role of epigenetic and genetic factors which could modulate HTR1B expression in the pharmacological response to antidepressants.

  17. A Stylistic Analysis of Break,Break,Break

    Institute of Scientific and Technical Information of China (English)

    李瑶

    2015-01-01

    Break, Break, Break is a poem by Alfred Lord Tennyson, the Poet Laureate during the Queen Victoria's reign. This exquisite little poem is wel known for the poet's grief-stricken feelings and heart-broken emotions over the premature death of his best friend, Arthur Henry Halam. Most of the previous studies on this poem focus on the emotional level to consider it as an elegy, expressing sorrow and lamentation for the death of a particular person. However, in order to have a deep understanding in general, this paper analyzes the poem based on the stylistic theory, concerning on the lexical level and the semantic level. It aims at helping the readers to cultivate a sense of appropriateness, to sharpen the understanding and appreciation of literary works and to achieve adaptation in translation.

  18. Long-Term Quality of Life and Pregnancy Outcomes of Differentiated Thyroid Cancer Survivors Treated by Total Thyroidectomy and I131 during Adolescence and Young Adulthood

    Directory of Open Access Journals (Sweden)

    Melanie Metallo

    2016-01-01

    Full Text Available Introduction. Differentiated thyroid cancer (DTC is rare and confers good prognosis. Long-term health related quality of life (HRQoL and pregnancy outcomes are not well known in subjects treated during adolescence and young adulthood. Methods. Cross-sectional analysis of HRQoL and global self-esteem, using SF-36 and ISP-25 surveys, and of pregnancy outcomes in female survivors of DTC treated by total thyroidectomy and I131 before age of 25 years. Results. Forty-five of 61 patients (74% responded to the survey. Cumulative I131 activity was ≤3.85 GBq in 18 subjects and >3.85 GBq in 27 subjects. Mean time from diagnosis was 7.6 ± 5.2 years for the group ≤ 3.85 GBq versus 16.9 ± 11.6 years for the group > 3.85 GBq (P 3.85 GBq and 10 in patients from the group ≤ 3.85 GBq. Frequency of miscarriages was of 17% (group > 3.85 GBq and 10% (group ≤ 3.85 GBq with 9 and 24 live births, respectively. No congenital malformations or first year mortality was noted. Conclusion. Long-term HRQoL, global self-esteem, and pregnancy outcomes are not affected in young female survivors of DTC.

  19. Long-Term Quality of Life and Pregnancy Outcomes of Differentiated Thyroid Cancer Survivors Treated by Total Thyroidectomy and I131 during Adolescence and Young Adulthood

    Science.gov (United States)

    Metallo, Melanie; Groza, Lelia; Brunaud, Laurent; Klein, Marc; Weryha, Georges; Feigerlova, Eva

    2016-01-01

    Introduction. Differentiated thyroid cancer (DTC) is rare and confers good prognosis. Long-term health related quality of life (HRQoL) and pregnancy outcomes are not well known in subjects treated during adolescence and young adulthood. Methods. Cross-sectional analysis of HRQoL and global self-esteem, using SF-36 and ISP-25 surveys, and of pregnancy outcomes in female survivors of DTC treated by total thyroidectomy and I131 before age of 25 years. Results. Forty-five of 61 patients (74%) responded to the survey. Cumulative I131 activity was ≤3.85 GBq in 18 subjects and >3.85 GBq in 27 subjects. Mean time from diagnosis was 7.6 ± 5.2 years for the group ≤ 3.85 GBq versus 16.9 ± 11.6 years for the group > 3.85 GBq (P 3.85 GBq and 10 in patients from the group ≤ 3.85 GBq. Frequency of miscarriages was of 17% (group > 3.85 GBq) and 10% (group ≤ 3.85 GBq) with 9 and 24 live births, respectively. No congenital malformations or first year mortality was noted. Conclusion. Long-term HRQoL, global self-esteem, and pregnancy outcomes are not affected in young female survivors of DTC. PMID:26977147

  20. Mental Health of Adults Treated in Adolescence with Scoliosis-Specific Exercise Program or Observed for Idiopathic Scoliosis

    Directory of Open Access Journals (Sweden)

    Maciej Płaszewski

    2014-01-01

    Full Text Available Objective. To examine general mental health in adult males and females, who in adolescence participated in a scoliosis-specific therapeutic exercise program or were under observation due to diagnosis of scoliosis. Design. Registry-based, cross-sectional study with retrospective data collection. Methods. Sixty-eight subjects (43 women aged 30.10 (25–39 years, with mild or moderate scoliosis (11–36° Cobb angle, and 76 (38 women nonscoliotic subjects, aged 30.11 (24–38 years, participated. The time period since the end of the exercise or observation regimes was 16.5 (12-26 years. Beck Depression Inventory (BDI and General Health Questionnaire (GHQ-28 scores were analyzed with the χ2 and U tests. Multiple regression analyses for confounders were also performed. Results. Intergroup differences of demographic characteristics were nonsignificant. Scoliosis, gender, participation in the exercise program, employment, and marital status were associated with BDI scores. The presence of scoliosis and participation in the exercise program manifested association with the symptoms. Higher GHQ-28 “somatic symptoms” subscale scores interacted with the education level. Conclusions. Our findings correspond to the reports of a negative impact of the diagnosis of scoliosis and treatment on mental health. The decision to introduce a therapeutic program in children with mild deformities should be made with judgment of potential benefits, risks, and harm.

  1. Adolescent idiopathic scoliosis (AIS treated with arthrodesis and posterior titanium instrumentation: 8 to 12 years follow up without late infection

    Directory of Open Access Journals (Sweden)

    Gluch Herbert

    2009-08-01

    Full Text Available Abstract Background There are no data in the peer-reviewed literature regarding long term results in patients treated for AIS with a posterior titanium instrumentation. Therefore we assessed the outcome in 50 patients treated by titanium implant. Methods A total of 50 patients with a mean age of 16.6 years were treated. In all patients, titanium hooks and pedicle screws were used in combination. The demographic data and the pre- and post-operative radiographs of all 50 patients were re-examined, and 49 of the 50 patients (98% attended a radiological and clinical follow up-examination on average 10.1 years post-operatively. The clinical results were recorded by means of the SRS 24 questionnaire. Results In the frontal plane, the mean pre-operative thoracic and lumbar curve had been 62.4° and 43.5° respectively, post-operatively the curves were reduced to 26.9° and 16.3°, resulting in a correction rate of 56.9% for thoracic and 62.5% for lumbar curve. At the follow up-evaluation, the Cobb angle of the thoracic and lumbar curve was 31.0° and 21.3° respectively, giving a final correction rate of 50.3% for thoracic, and 51.0% for lumbar curve. 7 of the 50 patients (14.3% had undergo revision surgery for complications, but complete implant removal was necessary in only one case. Analysis of the SRS 24 questionnaire showed an average score of 95.8 points. Conclusion Posterior titanium instrumentation is a safe and effective procedure in the surgical correction of AIS. In this retrospective study with small patient number, it shows favourable long-term results; in particular, the loss of correction is low, no late infection occurred and there was a very high survival rate of the implant itself.

  2. Refractory vasculitic ulcer of the toe in adolescent suffering from Systemic Lupus Erythematosus treated successfully with hyperbaric oxygen therapy

    Directory of Open Access Journals (Sweden)

    Mauro Angela

    2010-10-01

    Full Text Available Abstract Skin ulcers are a dangerous and uncommon complication of vasculitis. We describe the case of a teenager suffering from Systemic Lupus Erythematosus with digital ulcer resistant to conventional therapy, treated successfully with Hyperbaric Oxygen Therapy. The application of hyperbaric oxygen, which is used for the treatment of ischemic ulcers, is an effective and safe therapeutic option in patients with ischemic vasculitic ulcers in combination with immunosuppressive drugs. Further studies are needed to evaluate its role as primary therapy for this group of patients.

  3. Psychotherapies for Children and Adolescents

    Science.gov (United States)

    ... Facts for Families Guide Psychotherapy for Children and Adolescents: Different Types No. 86; updated February 2017 Psychotherapy ... Therapy (DBT) can be used to treat older adolescents who have chronic suicidal feelings/thoughts, engage in ...

  4. Scoliosis in Children and Adolescents

    Science.gov (United States)

    ... Questions and Answers about Scoliosis in Children and Adolescents This publication defines scoliosis and provides information about ... it is diagnosed and treated in children and adolescents. You may be interested in contacting one or ...

  5. Cost-effectiveness of extended-release methylphenidate in children and adolescents with attention-deficit/hyperactivity disorder sub-optimally treated with immediate release methylphenidate.

    Directory of Open Access Journals (Sweden)

    Jurjen van der Schans

    Full Text Available Attention-Deficit/Hyperactivity Disorder (ADHD is a common psychiatric disorder in children and adolescents. Immediate-release methylphenidate (IR-MPH is the medical treatment of first choice. The necessity to use several IR-MPH tablets per day and associated potential social stigma at school often leads to reduced compliance, sub-optimal treatment, and therefore economic loss. Replacement of IR-MPH with a single-dose extended release (ER-MPH formulation may improve drug response and economic efficiency.To evaluate the cost-effectiveness from a societal perspective of a switch from IR-MPH to ER-MPH in patients who are sub-optimally treated.A daily Markov-cycle model covering a time-span of 10 years was developed including four different health states: (1 optimal response, (2 sub-optimal response, (3 discontinued treatment, and (4 natural remission. ER-MPH options included methylphenidate osmotic release oral system (MPH-OROS and Equasym XL/Medikinet CR. Both direct costs and indirect costs were included in the analysis, and effects were expressed as quality-adjusted life years (QALYs. Univariate, multivariate as well as probabilistic sensitivity analysis were conducted and the main outcomes were incremental cost-effectiveness ratios.Switching sub-optimally treated patients from IR-MPH to MPH-OROS or Equasym XL/Medikinet CR led to per-patient cost-savings of €4200 and €5400, respectively, over a 10-year treatment span. Sensitivity analysis with plausible variations of input parameters resulted in cost-savings in the vast majority of estimations.This study lends economic support to switching patients with ADHD with suboptimal response to short-acting IR-MPH to long-acting ER-MPH regimens.

  6. 正天丸治疗青少年颈源性头痛的疗效观察%Clinical observation on treating adolescent cervicogenic headache with the Zhengtian pills

    Institute of Scientific and Technical Information of China (English)

    丁蓓; 谭为华; 刘丽英; 曾珍; 李志强; 蒋毅; 李鸣娟

    2013-01-01

    Objective: To investigate the clinical effect on treating adolescent cervicogenic headache with the Zhengtian pills. Methods:120 patients with adolescent cervicogenic headache were divided into two groups, 60 cases in each group. The treated group was treated by Zhengtian pills combined with flunarizine hydrochloride capsules, while the control group was treated by Zhengtian pill only. Both groups were treated four weeks. Results:The total efficiency of the treated group and control group was 95%and 78%, respectively. There was significant difference between two groups (P<0.05). Conclusion:The Zhengtian pills has a good therapeutic effect on patients with adolescent cervicogenic headache, and it worthy of widespread clinical application.%  目的:探讨正天丸治疗颈源性头痛的临床疗效。方法:120例颈源性头痛患者随机分为两组,治疗组60例采用正天丸联合氟桂利嗪治疗,对照组60例采用单用氟桂利嗪治疗,疗程均为4周。结果:治疗组总有效率95%;对照组总有效率78%。治疗组治疗效果明显高于对照组,两组比较有显著性差异(P<0.05)。结论:正天丸治疗颈源性头痛临床疗效好,使用方便,无明显不良反应,值得推广。

  7. 意象对话技术治疗青少年抑郁症的疗效观察%Clinical Observation on Imagery Dialogue Technique in Treating Adolescence Depression

    Institute of Scientific and Technical Information of China (English)

    李翠萍; 杜圣英; 张旺信

    2013-01-01

    探讨意象对话技术对青少年抑郁症的疗效.150例青少年抑郁症患者分为3组,意象组:单纯意象对话技术治疗;药物组:帕罗西汀治疗;联合组:帕罗西汀辅助认知治疗.患者随访1年,用汉密顿抑郁量表进行评定.结果显示,意象对话技术对青少年抑郁症的疗效与帕罗西汀联合认知疗法疗效相当,比单用帕罗西汀疗效好.%To explore the effect of Imagery Dialogue Technique in the treatment of adolescence depression, 150 cases with adolescence depression were randomly divided into three groups. Imagery dialogue group: treated with only imagery dialogue technique; drug therapy groups; treated with Paroxetine; joint therapy groups: treated with Paroxetine and cognitive behavioral therapy and assessed by Hamilton depression scale. The results showed the effect of imagery dialogue technique on adolescence depression was equivalent to the effect of Paroxetine combined with cognitive and was better than the effect of Paroxetine.

  8. Adolescent depression: a metasynthesis.

    Science.gov (United States)

    Dundon, Edith Emma

    2006-01-01

    Concerns about the adequate assessment and treatment of adolescent depression have been in the forefront of pediatric mental health literature in the recent past. While quantitative studies have provided valuable information, the voice of the adolescent has been lacking in the development of theory and treatment of this prevalent disorder. Using approach, a metasynthesis of six qualitative studies was conducted. This process revealed six themes that outline the course of adolescents who struggle with depression: (a) beyond the blues, (b) spiraling down and within, (c) breaking points, (d) seeing and being seen, (e) seeking solutions, and (f) taking control. Knowledge of the experience of adolescent depression will aid practitioners in recognition and early intervention for the increasing number of adolescents suffering with depression, as well as guide educational initiatives to provide needed information on the symptoms of depression and available resources for getting help.

  9. Consistency of Trend Break Point Estimator with Underspecified Break Number

    Directory of Open Access Journals (Sweden)

    Jingjing Yang

    2017-01-01

    Full Text Available This paper discusses the consistency of trend break point estimators when the number of breaks is underspecified. The consistency of break point estimators in a simple location model with level shifts has been well documented by researchers under various settings, including extensions such as allowing a time trend in the model. Despite the consistency of break point estimators of level shifts, there are few papers on the consistency of trend shift break point estimators in the presence of an underspecified break number. The simulation study and asymptotic analysis in this paper show that the trend shift break point estimator does not converge to the true break points when the break number is underspecified. In the case of two trend shifts, the inconsistency problem worsens if the magnitudes of the breaks are similar and the breaks are either both positive or both negative. The limiting distribution for the trend break point estimator is developed and closely approximates the finite sample performance.

  10. Opposite regulation of cannabinoid CB1 and CB2 receptors in the prefrontal cortex of rats treated with cocaine during adolescence.

    Science.gov (United States)

    García-Cabrerizo, Rubén; García-Fuster, M Julia

    2016-02-26

    The endocannabinoid system is implicated in the neurobiology of cocaine addiction, although it is not clear how cocaine regulates brain CB1 and CB2 receptors, especially during adolescence, a critical moment for shaping adult response to drug use. This study evaluated CB1 and CB2 protein levels in prefrontal cortex (PFC) and hippocampus (HC) by western blot analysis with specific and validated antibodies: (1) basally during adolescence (post-natal day PND 40, PND 47, PND 54), (2) by a sensitizing regimen of cocaine (15mg/kg, 7 days, i.p.) during different windows of adolescence vulnerability (PND 33-39, PND 40-46, PND 47-53), and (3) following repeated cocaine administration during adolescence (PND 33-39) in adulthood (PND 64). The results demonstrated a dynamic and opposite basal modulation of CB1 and CB2 receptors in PFC and HC during adolescence. CB1 receptor levels were increased while CB2 receptors were decreased as compared to adulthood with asymptotes values around mid adolescence (PND 47) both in PFC (CB1: +45±22, pCB1: +53±23, pCB1 (+55±10%, p<0.05) and CB2 (-25±10%, p<0.05) receptors when administered during early adolescence and only in PFC. However, the changes observed in PFC by repeated cocaine administration in adolescence were transient and did not endure into adulthood. These results identified a period of vulnerability during adolescence at which cocaine dysregulated the content of CB receptors in PFC, suggesting an opposite role for these receptors in the effects mediated by cocaine.

  11. Superconductivity and symmetry breaking

    Energy Technology Data Exchange (ETDEWEB)

    Sarasua, L.G., E-mail: sarasua@fisica.edu.uy [Instituto de Fisica, Facultad de Ciencias, Universidad de la Republica, Montevideo (Uruguay)

    2012-02-15

    In the present work we consider the relation between superconductivity and spontaneous gauge symmetry breaking (SGBS). We show that ODLRO does not require in principle SBGS, even in the presence of particle number fluctuations, by examining exact solutions of a fermionic pairing model. The criteria become equivalent if a symmetry breaking field is allowed, which can be attributed to the interaction with the environment. However, superconducting states without SBGS are not forbidden.

  12. Electroweak symmetry breaking

    Energy Technology Data Exchange (ETDEWEB)

    Chanowitz, M.S.

    1990-09-01

    The Higgs mechanism is reviewed in its most general form, requiring the existence of a new symmetry-breaking force and associated particles, which need not however be Higgs bosons. The first lecture reviews the essential elements of the Higgs mechanism, which suffice to establish low energy theorems for the scattering of longitudinally polarized W and Z gauge bosons. An upper bound on the scale of the symmetry-breaking physics then follows from the low energy theorems and partial wave unitarity. The second lecture reviews particular models, with and without Higgs bosons, paying special attention to how the general features discussed in lecture 1 are realized in each model. The third lecture focuses on the experimental signals of strong WW scattering that can be observed at the SSC above 1 TeV in the WW subenergy, which will allow direct measurement of the strength of the symmetry-breaking force. 52 refs., 10 figs.

  13. Why do we treat adolescent idiopathic scoliosis? What we want to obtain and to avoid for our patients. SOSORT 2005 Consensus paper

    Directory of Open Access Journals (Sweden)

    Negrini Stefano

    2006-04-01

    Full Text Available Abstract Background Medicine is a scientific art: once science is not clear, choices are made according to individual and collective beliefs that should be better understood. This is particularly true in a field like adolescent idiopathic scoliosis, where currently does not exist definitive scientific evidence on the efficacy either of conservative or of surgical treatments. Aim of the study To verify the philosophical choices on the final outcome of a group of people believing and engaged in a conservative treatment of idiopathic scoliosis. Methods We performed a multifaceted study that included a bibliometric analysis, a questionnaire, and a careful Consensus reaching procedure between experts in the conservative treatment of scoliosis (SOSORT members. Results The Consensus reaching procedure has shown to be useful: answers changed in a statistically significant way, and 9 new outcome criteria were included. The most important final outcomes were considered Aesthetics (100%, Quality of life and Disability (more than 90%, while more than 80% of preferences went to Back Pain, Psychological well-being, Progression in adulthood, Breathing function, Scoliosis Cobb degrees (radiographic lateral flexion, Needs of further treatments in adulthood. Discussion In the literature prevail outcome criteria driven by the contingent treatment needs or the possibility to have measurement systems (even if it seems that usual clinical and radiographic methods are given much more importance than more complex Disability or Quality of Life instruments. SOSORT members give importance to a wide range of outcome criteria, in which clinical and radiographic issues have the lowest importance. Conclusion We treat our patients for what they need for their future (Breathing function, Needs of further treatments in adulthood, Progression in adulthood, and their present too (Aesthetics, Disability, Quality of life. Technical matters, such as rib hump or radiographic lateral

  14. Nutritional Status of Adolescent Girls from Rural Communities of Tigray, Northern Ethiopia

    NARCIS (Netherlands)

    Mulugeta, A.; Hagos, F.; Stroecker, B.; Kruseman, G.; Linderhof, V.G.M.; Zenebe, A.; Mekonen, Y.; Girmay, G.

    2009-01-01

    Background: Addressing the nutritional needs of adolescents could be an important step towards breaking the vicious cycle of intergenerational malnutrition. Objective: Assess nutritional status of rural adolescent girls. Design: Cross-sectional. Methods: Anthropometric and socio-demographic informat

  15. 解剖式(牙合)垫治疗青少年磨牙症的临床研究%Clinical study on anatomic occlusal pad treating bruxism in the adolescents

    Institute of Scientific and Technical Information of China (English)

    高乐; 万澎波; 王亚亚; 王智勇; 郑美红

    2011-01-01

    目的 研究下颌解剖式(牙合)垫治疗青少年夜磨牙症的临床效果.方法 选取磨牙症青少年患者56例,采用下领解剖式(牙合)垫治疗,依据一定的疗效标准追踪随访,随访3、6、12个月,检查下颌解剖式(牙合)垫,戴用情况,包括美学评价、(牙合)关系、颞下领关节症状等.结果 下颌解剖式(牙合)垫治疗磨牙症的总有效率为100%.结论 采用下颌解剖式(牙合)垫治疗青少年夜磨牙症取得良好疗效.%Objective To study the clinical effects of mandibular anatomic occlusal pad on bruxism in adolescents. Methods A total of 56 adolescents with bruxism were selected and treated with mandibular anatomic occlusal pad. According to certain standard of curative effect, the patients were followed up for 3, 6 and 12 months after treatment to test the wearing conditions, including aesthetic evaluation, occlusal relationships, and symptoms of temporomandibular joint etc. Results Total effective rate of mandibular anatomic occlusal pad treating bruxism was 100%. Conclusion Anatomic occlusal pad has a good effect in treating bruxism in adolescents.

  16. Adolescent development

    Science.gov (United States)

    Development - adolescent; Growth and development - adolescent ... During adolescence, children develop the ability to: Understand abstract ideas. These include grasping higher math concepts, and developing moral ...

  17. Suicide attempts by exogenous intoxication among female adolescents treated at a reference hospital in the city of Recife-PE, Brazil

    Directory of Open Access Journals (Sweden)

    Juliana Lourenço de Araújo Veras

    2011-10-01

    Full Text Available This study aimed to assess cases of self-inflicted poisoning among adolescents reported by the Toxicological Care Center of a reference hospital in Recife-PE, Brazil. The data were collected between March and May 2010 from hospital charts and structured interviews with the participants and parents/guardians. Among the 25 cases of attempted suicide registered in the period, 21 were female adolescents, who made up the sample of the present study. The adolescents were between 13 and 19 years of age. Pesticides were the most frequent toxic agent used (61.9%. The results of the present study underscore the importance of studying suicide in this population, with a focus on family relations, in order to lay the foundation for the development of prevention and treatment programs for this vulnerable group.

  18. Treatment of retinal detachments with multiple breaks by pneumatic retinopexy.

    Science.gov (United States)

    McAllister, I L; Zegarra, H; Meyers, S M; Gutman, F A

    1987-07-01

    Pneumatic retinopexy is a recent innovation in the treatment of uncomplicated retinal detachments due to a superior retinal break extending for 30 degrees or less. We describe four patients with retinal detachments involving multiple breaks who were successfully treated by a modification of this technique. One case involved a calculation of the size of the gas bubble required to achieve tamponade of both breaks simultaneously. The gas was then administered in two sequential injections, as the volume was too large to be given in a single dose. In the remaining three cases, the gas bubble was rotated from the position of tamponade for one break into a position where tamponade of the second break or groups of breaks was achieved.

  19. Model Breaking Points Conceptualized

    Science.gov (United States)

    Vig, Rozy; Murray, Eileen; Star, Jon R.

    2014-01-01

    Current curriculum initiatives (e.g., National Governors Association Center for Best Practices and Council of Chief State School Officers 2010) advocate that models be used in the mathematics classroom. However, despite their apparent promise, there comes a point when models break, a point in the mathematical problem space where the model cannot,…

  20. A trial of d-cycloserine to treat the social deficit in older adolescents and young adults with autism spectrum disorders.

    Science.gov (United States)

    Urbano, Maria; Okwara, Leonore; Manser, Paul; Hartmann, Kathrin; Deutsch, Stephen I

    2015-01-01

    Autism spectrum disorders are difficult for older adolescents and young adults as impaired social communication affects the transition to adult life. d-Cycloserine, a partial glycine agonist at the N-methyl-d-aspartic acid receptor, was tested in a double-blind randomized trial in 20 older adolescents and young adults with autism spectrum disorders using two dosing strategies (50 mg daily versus 50 mg weekly) for 8 weeks with a 2-week follow-up after discontinuation. d-Cycloserine caused statistically and clinically significant improvement with no differentiation between dosing strategies on the Social Responsiveness Scale and the Aberrant Behavior Checklist before and after d-cycloserine administration.

  1. Chiral symmetry and chiral-symmetry breaking

    Energy Technology Data Exchange (ETDEWEB)

    Peskin, M.E.

    1982-12-01

    These lectures concern the dynamics of fermions in strong interaction with gauge fields. Systems of fermions coupled by gauge forces have a very rich structure of global symmetries, which are called chiral symmetries. These lectures will focus on the realization of chiral symmetries and the causes and consequences of thier spontaneous breaking. A brief introduction to the basic formalism and concepts of chiral symmetry breaking is given, then some explicit calculations of chiral symmetry breaking in gauge theories are given, treating first parity-invariant and then chiral models. These calculations are meant to be illustrative rather than accurate; they make use of unjustified mathematical approximations which serve to make the physics more clear. Some formal constraints on chiral symmetry breaking are discussed which illuminate and extend the results of our more explicit analysis. Finally, a brief review of the phenomenological theory of chiral symmetry breaking is presented, and some applications of this theory to problems in weak-interaction physics are discussed. (WHK)

  2. Social functioning in adulthood : Understanding long-term outcomes of adolescents with chronic pain/fatigue treated at inpatient rehabilitation programs

    NARCIS (Netherlands)

    Westendorp, T.; Verbunt, J. A.; Remerie, S. C.; de Blecourt, A. C. E.; van Baalen, B.; Smeets, R J E M

    2016-01-01

    Background: Chronic pain and fatigue are both common complaints in childhood and adolescence and often persist over time. The aim of the study was to investigate whether chronic pain/fatigue persists during adulthood and how former patients function and participate in society as adults. Methods: Thi

  3. Cost-Effectiveness of Extended-Release Methylphenidate in Children and Adolescents with Attention-Deficit/Hyperactivity Disorder Sub-Optimally Treated with Immediate Release Methylphenidate

    NARCIS (Netherlands)

    van der Schans, Jurjen; Kotsopoulos, Niko; Hoekstra, Pieter J.; Hak, Eelko; Postma, Maarten J.

    2015-01-01

    BACKGROUND: Attention-Deficit/Hyperactivity Disorder (ADHD) is a common psychiatric disorder in children and adolescents. Immediate-release methylphenidate (IR-MPH) is the medical treatment of first choice. The necessity to use several IR-MPH tablets per day and associated potential social stigma at

  4. Differences in quantification of DNA double-strand breaks assessed by 53BP1/γH2AX focus formation assays and the comet assay in mammalian cells treated with irradiation and N-acetyl-L-cysteine.

    Science.gov (United States)

    Kurashige, Tomomi; Shimamura, Mika; Nagayama, Yuji

    2016-06-01

    The biological effect of ionizing radiation (IR) on genomic DNA is thought to be either direct or indirect; the latter is mediated by IR induction of free radicals and reactive oxygen species (ROS). This study was designed to evaluate the effect of N-acetyl-L-cysteine (NAC), a well-known ROS-scavenging antioxidant, on IR induction of genotoxicity, cytotoxicity and ROS production in mammalian cells, and aimed to clarify the conflicting data in previous publications. Although we clearly demonstrate the beneficial effect of NAC on IR-induced genotoxicity and cytotoxicity (determined using the micronucleus assay and cell viability/clonogenic assays), the data on NAC's effect on DNA double-strand break (DSB) formation were inconsistent in different assays. Specifically, mitigation of IR-induced DSBs by NAC was readily detected by the neutral comet assay, but not by the γH2AX or 53BP1 focus assays. NAC is a glutathione precursor and exerts its effect after conversion to glutathione, and presumably it has its own biological activity. Assuming that the focus assay reflects the biological responses to DSBs (detection and repair), while the comet assay reflects the physical status of genomic DNA, our results indicate that the comet assay could readily detect the antioxidant effect of NAC on DSB formation. However, NAC's biological effect might affect the detection of DSB repair by the focus assays. Our data illustrate that multiple parameters should be carefully used to analyze DNA damage when studying potential candidates for radioprotective compounds.

  5. Emotional well-being in children and adolescents treated with atomoxetine for attention-deficit/hyperactivity disorder: Findings from a patient, parent and physician perspective using items from the pediatric adverse event rating scale (PAERS

    Directory of Open Access Journals (Sweden)

    Dittmann Ralf W

    2008-05-01

    Full Text Available Abstract Background The objective of this analysis was to measure changes in items on the Pediatric Adverse Event Rating Scale (PAERS that relate to emotional well-being of children and adolescents with Attention-Deficit/Hyperactivity Disorder (ADHD during treatment with atomoxetine for up to 24 weeks from the perspective of the patient, the parent, and the physician. Methods Patients aged 6–17 years with ADHD were treated with atomoxetine (target dose 1.2 mg/kg/day. In the two studies on which this secondary analysis is based the PAERS was used to assess the tolerability of atomoxetine in children and adolescents. This scale has a total of 48 items. The ten items that reflect emotional well-being were selected to measure changes over time from a patient, parent, and physician perspective. Results 421 patients were treated with atomoxetine. 355 patients completed the 8-week treatment period, and 260 patients completed the 24-week treatment period. The ten items that reflect emotional well-being were grouped in five dimensions: depressed mood, self-harm, irritability/agitation, drowsiness, and euphoria. The scores of these dimensions decreased over time, both from a patient as well as from a parent and physician perspective. Only the dimension self-harm was extremely low at baseline and stayed low over time. The mean scores for the ten items depended on the rater perspective. Conclusion The emotional well-being of children and adolescents with ADHD improved in terms of depressed mood, irritability/agitation, drowsiness, and euphoria during treatment with atomoxetine for up to 24 weeks.

  6. Breaking News as Radicalisation

    DEFF Research Database (Denmark)

    Hartley, Jannie Møller

    The aim of the paper is to make explicit how the different categories are applied in the online newsroom and thus how new categories can be seen as positioning strategies in the form of radicalisations of already existing categories. Thus field theory provides us with tools to analyse how online...... journalists are using the categorisations to create hierarchies within the journalistic field in order to position themselves as specialists in what Tuchman has called developing news, aiming and striving for what today is know as breaking news and the “exclusive scoop,” as the trademark of online journalism...... provides us with the following two research questions: How does the category of breaking news fit into Tuchmans typology related to time, planning and technology? What types of stories are providing journalistic capital and how are online news stories categorised relatively within the journalistic field?...

  7. Predicting appointment breaking.

    Science.gov (United States)

    Bean, A G; Talaga, J

    1995-01-01

    The goal of physician referral services is to schedule appointments, but if too many patients fail to show up, the value of the service will be compromised. The authors found that appointment breaking can be predicted by the number of days to the scheduled appointment, the doctor's specialty, and the patient's age and gender. They also offer specific suggestions for modifying the marketing mix to reduce the incidence of no-shows.

  8. Single sector supersymmetry breaking

    Energy Technology Data Exchange (ETDEWEB)

    Luty, Markus A.; Terning, John

    1999-03-18

    We review recent work on realistic models that break supersymmetry dynamically and give rise to composite quarks and leptons, all in a single sector. These models have a completely natural suppression of flavor-changing neutral currents, and the hierarchy of Yukawa couplings is explained by the dimensionality of composite states. The generic signatures are unification of scalar masses with different quantum numbers at the compositeness scale, and lighter gaugino, Higgsino, and third-generation sfermion masses.

  9. Factors associated with caregiver burden among pharmacotherapy-treated children/adolescents with ADHD in the Caregiver Perspective on Pediatric ADHD survey in Europe

    Directory of Open Access Journals (Sweden)

    Fridman M

    2017-02-01

    Full Text Available Moshe Fridman,1 Tobias Banaschewski,2 Vanja Sikirica,3 Javier Quintero,4 M Haim Erder,3 Kristina S Chen5 1AMF Consulting, Inc., Los Angeles, CA, USA; 2Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim of the University of Heidelberg, Mannheim, Germany; 3Global Health Economics Outcomes Research and Epidemiology, Shire, Wayne, PA, USA; 4Psychiatry Department, Hospital Universitario Infanta Leonor, Complutense University, Madrid, Spain; 5Global Health Economics Outcomes Research and Epidemiology, Shire, Lexington, MA, USA Background: Burden on caregivers of children/adolescents with attention-deficit/hyperactivity disorder (ADHD is multidimensional, but incompletely understood. Objective: To analyze caregiver burden across the concepts of work, social/family life, and parental worry/stress, in relation to selected contributing factors. Methods: The online Caregiver Perspective on Pediatric ADHD survey was fielded in ten European countries. Analysis included children/adolescents (6–17 years who were receiving/had received ADHD pharmacotherapy in the previous 6 months. Caregivers recorded their child’s/adolescent’s symptoms “on”/“off” medication (ie, when the caregiver reported that the child/adolescent forgot/chose not to take medication, before the onset of medication effect, or medication worn off. Effects of ADHD severity, comorbidities, and medication adherence on each burden outcome were assessed (multiple regression models. Results: In total, 2,326 caregivers were included (children/adolescents’ mean age: 11.5 years, 80% male. Caregivers reported missed/altered work, avoiding social activity, increased parental worry/stress, and strain on family life, despite using ADHD pharmacotherapy. Child/adolescent comorbidities and ADHD severity were significantly related to all burden concepts measured; the strongest comorbidity associations were with altered

  10. Clinical progression of autoimmune thyroiditis in children and adolescents treated at the Instituto Nacional de Salud del Niño

    OpenAIRE

    Núñez Almache, Oswaldo; Facultad de Medicina, Universidad Nacional Federico Villarreal, Lima, Perú; Servicio de Endocrinología, Instituto Nacional de Salud del Niño, Lima, Perú; Del Aguila Villar, Carlos; Facultad de Medicina, Universidad Nacional Federico Villarreal, Lima, Perú; Servicio de Endocrinología, Instituto Nacional de Salud del Niño, Lima, Perú; Chavez Tejada, Eliana; Servicio de Endocrinología, Instituto Nacional de Salud del Niño (INSN), Lima; Espinoza Robles, Oscar; Servicio de Endocrinología, Instituto Nacional de Salud del Niño, Lima, Perú; Pinto Ibárcena, Paola; Servicio de Endocrinología, Instituto Nacional de Salud del Niño (INSN), Lima; Calagua Quispe, Martha; Servicio de Endocrinología, Instituto Nacional de Salud del Niño, Lima, Perú; De los Santos La Torre, Miguel; Servicio de Endocrinología, Instituto Nacional de Salud del Niño (INSN), Lima

    2016-01-01

    Introduction. Autoimmune thyroiditis is the most common cause of hypothyroidism in children. Clinical diagnosis depends on biochemical condition and monitoring is essential to adopt therapeutic measures and ensure proper growth and development. Objective. To describe the clinical progression of autoimmune thyroiditis in children and adolescents. Design. Retrospective, longitudinal series of cases study. Setting. Department of Endocrinology, Instituto Nacional de Salud del Niño, Lima, Peru (a ...

  11. Breaking bad news in cancer patients

    Directory of Open Access Journals (Sweden)

    Apostolos Konstantis

    2015-01-01

    Full Text Available Objective: In a regional hospital, many patients are newly diagnosed with cancer. Breaking the bad news in these patients and their relatives is a tough task. Many doctors are not experienced in talking to patients about death or death-related diseases. In recent years, there have been great efforts to change the current situation. The aim of this study was to investigate the experience and education of medical personnel in breaking bad news in a secondary hospital. Materials and Methods: 59 doctors from General Hospital of Komotini, Greece were included in the study. All the doctors were in clinical specialties that treated cancer patients. A brief questionnaire was developed based on current guidelines such as Baile/SPIKES framework and the ABCDE mnemonic. Results: Residents are involved in delivering bad news less frequently than specialists. Only 21 doctors (35.59% had specific training on breaking bad news. 20 doctors (33.90% were aware of the available techniques and protocols on breaking bad news. 47 doctors (79.66% had a consistent plan for breaking bad news. 57 (96.61% delivered bad news in a quiet place, 53 (89.83% ensured no interruptions and enough time, 53 (89.83% used simple words and 54 (91.53% checked for understanding and did not rush through the news. 46 doctors (77.97% allowed relatives to determine patient′s knowledge about the disease. Conclusions: There were low rates of specific training in breaking bad news. However, the selected location, the physician′s speech and their plan were according to current guidelines.

  12. Breaking Bad News in Cancer Patients

    Science.gov (United States)

    Konstantis, Apostolos; Exiara, Triada

    2015-01-01

    Objective: In a regional hospital, many patients are newly diagnosed with cancer. Breaking the bad news in these patients and their relatives is a tough task. Many doctors are not experienced in talking to patients about death or death-related diseases. In recent years, there have been great efforts to change the current situation. The aim of this study was to investigate the experience and education of medical personnel in breaking bad news in a secondary hospital. Materials and Methods: 59 doctors from General Hospital of Komotini, Greece were included in the study. All the doctors were in clinical specialties that treated cancer patients. A brief questionnaire was developed based on current guidelines such as Baile/SPIKES framework and the ABCDE mnemonic. Results: Residents are involved in delivering bad news less frequently than specialists. Only 21 doctors (35.59%) had specific training on breaking bad news. 20 doctors (33.90%) were aware of the available techniques and protocols on breaking bad news. 47 doctors (79.66%) had a consistent plan for breaking bad news. 57 (96.61%) delivered bad news in a quiet place, 53 (89.83%) ensured no interruptions and enough time, 53 (89.83%) used simple words and 54 (91.53%) checked for understanding and did not rush through the news. 46 doctors (77.97%) allowed relatives to determine patient's knowledge about the disease. Conclusions: There were low rates of specific training in breaking bad news. However, the selected location, the physician's speech and their plan were according to current guidelines. PMID:25709183

  13. Breaking the Waves

    DEFF Research Database (Denmark)

    Christensen, Poul Rind; Kirketerp, Anne

    2006-01-01

    The paper shortly reveals the history of a small school - the KaosPilots - dedicated to educate young people to carriers as entrepreneurs. In this contribution we want to explore how the KaosPilots managed to break the waves of institutionalised concepts and practices of teaching entrepreneurship....... Following the so-called 'Dogma' concept developed by Danish filmmakers, this contribution aim to explore the key elements making up the recipes guiding the entrepreneurship training program exercised by the school. Key factors forming a community of learning practice are outlined as well as the critical...... pedagogical elements on which the education in entrepreneurship rests....

  14. Symmetry breaking. 2. ed.

    Energy Technology Data Exchange (ETDEWEB)

    Strocchi, F. [Scuola Normale Superiore, Classe di Scienze, Pisa (Italy)

    2008-07-01

    This new edition of Prof. Strocchi's well received primer on rigorous aspects of symmetry breaking presents a more detailed and thorough discussion of the mechanism of symmetry breaking in classical field theory in relation with the Noether theorem. Moreover, the link between symmetry breaking without massless Goldstone bosons in Coulomb systems and in gauge theories is made more explicit in terms of the delocalized Coulomb dynamics. Furthermore, the chapter on the Higgs mechanism has been significantly expanded with a non-perturbative treatment of the Higgs phenomenon, at the basis of the standard model of particle physics, in the local and in the Coulomb gauges. Last but not least, a subject index has been added and a number of misprints have been corrected. From the reviews of the first edition: The notion of spontaneous symmetry breaking has proven extremely valuable, the problem is that most derivations are perturbative and heuristic. Yet mathematically precise versions do exist, but are not widely known. It is precisely the aim of his book to correct this unbalance. - It is remarkable to see how much material can actually be presented in a rigorous way (incidentally, many of the results presented are due to Strocchi himself), yet this is largely ignored, the original heuristic derivations being, as a rule, more popular. - At each step he strongly emphasizes the physical meaning and motivation of the various notions introduced, a book that fills a conspicuous gap in the literature, and does it rather well. It could also be a good basis for a graduate course in mathematical physics. It can be recommended to physicists as well and, of course, for physics/mathematics libraries. J.-P. Antoine, Physicalia 28/2, 2006 Strocchi's main emphasis is on the fact that the loss of symmetric behaviour requires both the non-symmetric ground states and the infinite extension of the system. It is written in a pleasant style at a level suitable for graduate students in

  15. New strategies to ensure good patient–physician communication when treating adolescents and young adults with cancer: the proposed model of the Milan Youth Project

    Directory of Open Access Journals (Sweden)

    Magni MC

    2015-08-01

    Full Text Available Maria Chiara Magni,1 Laura Veneroni,1 Carlo Alfredo Clerici,2 Tullio Proserpio,3 Giovanna Sironi,1 Michela Casanova,1 Stefano Chiaravalli,1 Maura Massimino,1 Andrea Ferrari1 1Pediatric Oncology Unit, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy; 2Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy; 3Pastoral Care Unit, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy Abstract: Adolescence is a particularly complex time of life, entailing physiological, psychological, and social changes that further the individual's cognitive, emotional, and social growth. Being diagnosed with cancer at this time can have important consequences on an individual's emotional and physical development, and adolescent and young adult cancer patients have particular medical and psychosocial needs. Patient–physician communications are important in any clinical relationship, but fundamental in the oncological sphere because their quality can affect the patient–physician relationship, the therapeutic alliance, and patient compliance. A major challenge when dealing with adolescent and young adult patients lies in striking the right balance between their need and right to understand their disease, treatment, and prognosis, and the need for them to remain hopeful and to protect their emotional sensitivity. We herein describe the activities of the Youth Project of the Istituto Nazionale Tumori in Milan, Italy in order to share a possible model of interaction with these special patients and the tactics our group has identified to help them communicate and share their thoughts. This model implies not only the involvement of a multidisciplinary team, including psychologists and spirituality experts, but also the constitution of dedicated creative activities to give patients the opportunity to express feelings they would otherwise never feel at ease putting into words. These efforts seek the goal to minimize the potentially

  16. A randomized controlled trial testing an adherence-optimized Vitamin D regimen to mitigate bone change in adolescents being treated for acute lymphoblastic leukemia.

    Science.gov (United States)

    Orgel, Etan; Mueske, Nicole M; Sposto, Richard; Gilsanz, Vicente; Wren, Tishya A L; Freyer, David R; Butturini, Anna M; Mittelman, Steven D

    2017-02-20

    Adolescents with acute lymphoblastic leukemia (ALL) develop osteopenia early in therapy, potentially exacerbated by high rates of concurrent Vitamin D deficiency. We conducted a randomized clinical trial testing a Vitamin D-based intervention to improve Vitamin D status and reduce bone density decline. Poor adherence to home supplementation necessitated a change to directly observed therapy (DOT) with intermittent, high-dose Vitamin D3 randomized versus standard of care (SOC). Compared to SOC, DOT Vitamin D3 successfully increased trough Vitamin 25(OH)D levels (p = .026) with no residual Vitamin D deficiency, 100% adherence to DOT Vitamin D3, and without associated toxicity. However, neither Vitamin D status nor supplementation impacted bone density. Thus, this adherence-optimized intervention is feasible and effective to correct Vitamin D deficiency in adolescents during ALL therapy. Repletion of Vitamin D and calcium alone did not mitigate osteopenia, however, and new, comprehensive approaches are needed to address treatment-associated osteopenia during ALL therapy.

  17. Why adolescents use substances of abuse.

    Science.gov (United States)

    Duhigg, Daniel

    2013-08-01

    In summary, adolescent substance use is associated with a variety of risks. Using a nonjudgmental and collaborative approach to treating adolescent substance users can yield positive results. Motivational interviewing and the adolescent community reinforcement approach are evidence-based, nonpharmacologic treatments for teens with substance use disorders.

  18. Dynamical Supersymmetry Breaking

    CERN Document Server

    Shadmi, Y; Shadmi, Yael; Shirman, Yuri

    2000-01-01

    Supersymmetry is one of the most plausible and theoretically motivated frameworks for extending the Standard Model. However, any supersymmetry in Nature must be a broken symmetry. Dynamical supersymmetry breaking (DSB) is an attractive idea for incorporating supersymmetry into a successful description of Nature. The study of DSB has recently enjoyed dramatic progress, fueled by advances in our understanding of the dynamics of supersymmetric field theories. These advances have allowed for direct analysis of DSB in strongly coupled theories, and for the discovery of new DSB theories, some of which contradict early criteria for DSB. We review these criteria, emphasizing recently discovered exceptions. We also describe, through many examples, various techniques for directly establishing DSB by studying the infrared theory, including both older techniques in regions of weak coupling, and new techniques in regions of strong coupling. Finally, we present a list of representative DSB models, their main properties, an...

  19. Corpuscular Breaking of Supersymmetry

    CERN Document Server

    Dvali, Gia

    2014-01-01

    Are topological solitons elementary or composites? We answer this question by drawing up a corpuscular formalism in which solitons are coherent states of quantum constituents. This naturally leads to a functional integral representation, in which the classical saddle point is reached as the most probable distribution of corpuscles in the $\\hbar = 0$ limit and where quantum corpuscular corrections correspond to excursions away from such a distribution that occur only for finite $\\hbar$. Several striking features come up. Topological charge emerges as a collective flow of quantum numbers carried by individual corpuscles. Moreover, the corpuscular corrections are not reducible to any known form of quantum corrections, such as loop expansions in the coupling constant $\\hbar g^2$ or semiclassical $e^{-1/\\hbar g^2}$ effects. Corpuscular corrections are stronger and appear already at order $\\sqrt{\\hbar g^2}$. In SUSY theories quantum corpuscular corrections generically break supersymmetry. We show that a domain wall...

  20. Break the Pattern!

    DEFF Research Database (Denmark)

    Hasse, Cathrine; Trentemøller, Stine

    Break the Pattern! A critical enquiry into three scientific workplace cultures: Hercules, Caretakers and Worker Bees is the third publication of the international three year long project "Understanding Puzzles in the Gendered European Map" (UPGEM). By contrasting empirical findings from academic...... workplaces in the five UPGEM-countries (Denmark, Estonia, Finland, Italy and Poland) we identify three clusters of cultural patterns in physics as culture. We call these Hercules, Caretakers and Worker Bees. We also consider the influence of national cultural historical processes on the scientific culture...... (physics in culture) and discuss how physics as and in culture influence the perception of science, of work and family life, of the interplay between religion and science as well as how physics as culture can either hinder or promote the career of female scientists....

  1. Dynamical (Super)Symmetry Breaking

    CERN Document Server

    Murayama, H

    2001-01-01

    Dynamical Symmetry Breaking (DSB) is a concept theorists rely on very often in the discussions of strong dynamics, model building, and hierarchy problems. In this talk, I will discuss why this is such a permeating concept among theorists and how they are used in understanding physics. I also briefly review recent progress in using dynamical symmetry breaking to construct models of supersymmetry breaking and fermion masses.

  2. Numerical analysis of etoposide induced DNA breaks.

    Directory of Open Access Journals (Sweden)

    Aida Muslimović

    Full Text Available BACKGROUND: Etoposide is a cancer drug that induces strand breaks in cellular DNA by inhibiting topoisomerase II (topoII religation of cleaved DNA molecules. Although DNA cleavage by topoisomerase II always produces topoisomerase II-linked DNA double-strand breaks (DSBs, the action of etoposide also results in single-strand breaks (SSBs, since religation of the two strands are independently inhibited by etoposide. In addition, recent studies indicate that topoisomerase II-linked DSBs remain undetected unless topoisomerase II is removed to produce free DSBs. METHODOLOGY/PRINCIPAL FINDINGS: To examine etoposide-induced DNA damage in more detail we compared the relative amount of SSBs and DSBs, survival and H2AX phosphorylation in cells treated with etoposide or calicheamicin, a drug that produces free DSBs and SSBs. With this combination of methods we found that only 3% of the DNA strand breaks induced by etoposide were DSBs. By comparing the level of DSBs, H2AX phosphorylation and toxicity induced by etoposide and calicheamicin, we found that only 10% of etoposide-induced DSBs resulted in histone H2AX phosphorylation and toxicity. There was a close match between toxicity and histone H2AX phosphorylation for calicheamicin and etoposide suggesting that the few etoposide-induced DSBs that activated H2AX phosphorylation were responsible for toxicity. CONCLUSIONS/SIGNIFICANCE: These results show that only 0.3% of all strand breaks produced by etoposide activate H2AX phosphorylation and suggests that over 99% of the etoposide induced DNA damage does not contribute to its toxicity.

  3. Electroweak breaking in supersymmetric models

    CERN Document Server

    Ibáñez, L E

    1992-01-01

    We discuss the mechanism for electroweak symmetry breaking in supersymmetric versions of the standard model. After briefly reviewing the possible sources of supersymmetry breaking, we show how the required pattern of symmetry breaking can automatically result from the structure of quantum corrections in the theory. We demonstrate that this radiative breaking mechanism works well for a heavy top quark and can be combined in unified versions of the theory with excellent predictions for the running couplings of the model. (To be published in ``Perspectives in Higgs Physics'', G. Kane editor.)

  4. Fasciola hepatica: histological demonstration of apoptosis in the reproductive organs of flukes of triclabendazole-sensitive and triclabendazole-resistant isolates, and in field-derived flukes from triclabendazole-treated hosts, using in situ hybridisation to visualise endonuclease-generated DNA strand breaks.

    Science.gov (United States)

    Hanna, R E B; Forster, F I; Brennan, G P; Fairweather, I

    2013-01-31

    Investigation of the triclabendazole (TCBZ) resistance status of populations of Fasciola hepatica in field cases of fasciolosis, where treatment failure has been reported, can be supported by histological examination of flukes collected from recently treated hosts. In TCBZ-sensitive flukes (TCBZ-S) exposed to TCBZ metabolites for 1-4days in vivo, but not in TCBZ-resistant flukes (TCBZ-R), morphological changes suggestive of apoptosis occur in cells undergoing meiosis or mitosis in the testis, ovary and vitelline follicles. In order to verify or refute the contention that efficacy of TCBZ treatment is associated with apoptosis in the reproductive organs of flukes, histological sections of TCBZ-S (Cullompton isolate) flukes and TCBZ-R (Sligo isolate) flukes were subjected to the TdT-mediated dUDP nick end labelling (TUNEL) in situ hybridisation method, a commercially available test specifically designed to label endonuclease-induced DNA strand breaks associated with apoptosis. Additionally, sections of in vivo-treated and untreated flukes originating from field outbreaks of suspected TCBZ-S and TCBZ-R fasciolosis were labelled by the TUNEL method. It was found that in treated TCBZ-S flukes, strong positive labelling indicating apoptosis was associated with morphologically abnormal cells undergoing mitosis or meiosis in the testis, ovary and vitelline follicles. Background labelling in the positive testis sections was attributed to heterophagy of cell debris by the sustentacular tissue. The triggering of apoptosis was probably related to failure of spindle formation at cell division, supporting the contention that TCBZ inhibits microtubule formation. In treated TCBZ-R (Sligo Type 1) flukes, and in treated flukes from field outbreaks of suspected TCBZ-R fasciolosis, no significant labelling was observed, while sections of fluke derived from a field case of fasciolosis where TCBZ resistance was not suspected were heavily labelled. Light labelling was associated with the

  5. Asthma care for children and adolescents

    OpenAIRE

    2015-01-01

    Background: Asthma is one of the most common chronic diseases among young children and adolescents. With high quality health care, most children and adolescents with asthma can live an active and normal life. Yet, many children and adolescents have uncontrolled asthma, with symptoms and exacerbations which may affect their daily life. Adolescence is a sensitive period and asthma may be difficult to treat due to poor adherence to treatment. Little is known about health care professionals’ adhe...

  6. On partially entanglement breaking channels

    CERN Document Server

    Chruscinski, D; Chruscinski, Dariusz; Kossakowski, Andrzej

    2005-01-01

    Using well known duality between quantum maps and states of composite systems we introduce the notion of Schmidt number of a quantum channel. It enables one to define classes of quantum channels which partially break quantum entanglement. These classes generalize the well known class of entanglement breaking channels.

  7. Entanglement–breaking indices

    Energy Technology Data Exchange (ETDEWEB)

    Lami, L. [Scuola Normale Superiore, I-56126 Pisa (Italy); Giovannetti, V. [NEST, Scuola Normale Superiore and Istituto Nanoscienze-CNR, I-56127 Pisa (Italy)

    2015-09-15

    We study a set of new functionals (called entanglement–breaking indices) which characterize how many local iterations of a given (local) quantum channel are needed in order to completely destroy the entanglement between the system of interest over which the transformation is defined and an external ancilla. The possibility of contrasting the noisy effects introduced by the channel iterations via the action of intermediate (filtering) transformations is analyzed. We provide some examples in which our functionals can be exactly calculated. The differences between unitary and non-unitary filtering operations are analyzed showing that, at least for systems of dimension d larger than or equal to 3, the non-unitary choice is preferable (the gap between the performances of the two cases being divergent in some cases). For d = 2 (qubit case), on the contrary, no evidences of the presence of such gap is revealed: we conjecture that for this special case unitary filtering transformations are optimal. The scenario in which more general filtering protocols are allowed is also discussed in some detail. The case of a depolarizing noise acting on a two–qubit system is exactly solved in a general case.

  8. Breaking the silence

    DEFF Research Database (Denmark)

    Konradsen, Hanne; Kirkevold, Marit; McCallin, Antoinette

    2012-01-01

    Little is known about the psychosocial effects of facial disfigurement. We present the results of a qualitative study following 15 patients who had been surgically treated for head, neck, or eye cancer over the course of their first postoperative year. Taped nurse-patient conversations and indivi...... a disfigured person to a person with a disfigurement. The model explains the process of adjustment and demonstrates various elements that could be used in interventions targeting patients who experience psychosocial problems....

  9. Efficacy analysis for adolescent idiopathic scoliosis treated with Milwaukee or Boston orthosis%Milwaukee和Boston支具治疗青少年特发性脊柱侧凸的疗效分析

    Institute of Scientific and Technical Information of China (English)

    张宏其; 黄术; 盛斌; 高琪乐; 王昱翔; 郭超峰; 唐明星

    2011-01-01

    目的 评估Milwaukee和Boston支具不同佩戴方式对于治疗青少年脊柱侧凸疗效.方法 回顾总结2004年2月至2009年3月间对85例骨骼发育未成熟的青少年特发性脊柱侧凸患儿的诊治.支具治疗的57例患儿,分别接受颈胸腰骶支具( CTLSO) -Milwaukee支具(28例)和胸腰骶矫形支具(TLSO) -Boston支具(29例)并辅以体操矫正.其中30例规律佩戴,每天21 ~23 h;27例间断佩戴,每天6 ~ 15 h;另28例未佩戴相应支具.每3~6个月定期观察患儿Cobb角和Risser征,复查时均摄佩带和卸下支具站立位全脊柱正侧位X线片及外观大体像.结果 73例获得2~5年的临床随访,时间(26.3±33.7)个月.Milwaukee支具组:规律佩戴支具类有效率达91.67%(11/12),间断佩戴支具类有效率达56.25%(9/16),未佩戴支具类有效率为20%(4/20).经比较Milwaukee支具规律类优于支具间断类和无支具类(P<0.05).Boston支具组:规律佩戴支具类有效率达88.89%(16/18),间断佩戴支具类有效率达54.55%(6/11),未佩戴支具类有效率为25%(2/8).经比较Boston支具规律类优于支具间断类和无支具类(P<0.05).文中支具和患儿选择不同,因此未对两种支具临床疗效对比.结论 两种支具均应坚持正确规律的佩戴,两种支具组规律类疗效优于各支具组间断类和无支具类,对于符合支具治疗指征的AIS患儿疗效确切.%Objective To evaluate the efficacy about the different wearing manner with Milwaukee and Boston for the treatment of adolescent idiopathic scoliosis (AIS).Methods Retrospectively summarization and analysis was performed in 85 adolescent patients with idiopathic scoliosis who were treated from February 2004 to March 2009.The skeletal growth of them had not completed.There were 57 cases who received brace treatment.In them,28 were treated with (CTLSO) Milwaukee brace,and the rest were treated with (TLSO) Boston brace and orthopedic gymnastics.The 30 cases wear

  10. Adolescents' Explanations for Romantic Dissolutions: A Developmental Perspective

    Science.gov (United States)

    Connolly, Jennifer; McIsaac, Caroline

    2009-01-01

    Our objective was to examine the prevalence and developmental significance of romantic break-ups in adolescence, a relatively unexplored area of study. We examined their occurrence in a sample of 910 adolescents, first noting the frequency of these events across age, gender, and romantic experience, and then analyzing the dissolution explanations…

  11. Treating Infertility

    Science.gov (United States)

    ... Education & Events Advocacy For Patients About ACOG Treating Infertility Home For Patients Search FAQs Treating Infertility Page ... Treating Infertility FAQ137, March 2015 PDF Format Treating Infertility Gynecologic Problems What is infertility? What treatment options ...

  12. Breaking beer bottles with cavitation

    Science.gov (United States)

    Jung, Sunny; Fontana, Jake; Palffy-Muhoray, Peter; Shelley, Michael

    2009-03-01

    Hitting the top of a beer bottle, nearly full of water, with an open hand can cause the bottle to break, with the bottom separating from upper section. We have studied this phenomenon using a high-speed camera, and observed the formation, coalescence and collapse of bubbles. The breaking of glass is due to cavitation, typically occurring near the bottom edge. We make numerical estimates of the relevant physical parameters, and compare these with experimental observations.

  13. The symmetry breaking phenomenon in anharmonic oscillator model

    CERN Document Server

    Mastine, Antonio Carlos; Natti, Erica Regina Takano

    2010-01-01

    In this article a non-perturbative time-dependent technique is used to treat the initial value problem, in Quantum Mechanics context, for a non-equilibrium self-interacting fermionic system in the presence of an external magnetic field. Particularly, in mean-field regime, we study the dynamical symmetry breaking phenomenon, identifying the physical processes associated.

  14. Fetal cerebral ventricular atria width of 8-10mm: A possible prenatal risk factor for adolescent treated Attention Deficit Hyperactivity Disorder (ADHD).

    Science.gov (United States)

    Kivilevitch, Zvi; Gabis, Lidia V; Katorza, Eldad; Achiron, Reuven

    2016-01-01

    The purpose of our research was to study the in-utero and long term post-natal outcome of fetal isolated cerebral ventricular atria width between 8 and 10mm. We conducted a retrospective, observational, case-control study, of low risk pregnant women, between 1993 and 2001. One hundred and forty one fetuses with isolated cerebral ventricular atria width between 8 and 10mm, corresponding to 2-4 standard deviations above the mean, and 309 controls, with atrial width below this level, were included for the analysis. Clinical data concerning pre and post-natal outcome was retrieved from computerized medical records. Matching of cases with controls was based on age, with a ratio of 2-3 controls per case. Statistical analysis included: T-test, Chi-Square, and Multiple Logistic Regression analysis. The study group was characterized by a predominance of male gender, left side involvement, and higher birth weight, compared to the control group. Long term post-natal follow-up at a mean age of 12.7 years (±1.9) demonstrated an adjusted odds ratio of 2.589 (95% CI 1.415-4.737, p=0.001), being diagnosed as Attention Deficit Hyperactivity Disorder (ADHD), and treated by Methylphenidate (Ritalin(®)), during childhood, compared to the control group (23.6% and 10.0% respectively) (p=0.001). Cerebral atria width was an independent factor, controlled for the only two significant variants between groups, gender and weight over 90th centile. In conclusions, our preliminary results show that fetuses with prenatal finding of isolated cerebral ventricular atria width between 8 and 10mm are more likely of being diagnosed and treated as ADHD during childhood.

  15. The incidence of caries and white spot lesions in orthodontically treated adolescents with a comprehensive caries prophylactic regimen--a prospective study.

    Science.gov (United States)

    Hadler-Olsen, Sigurd; Sandvik, Kristin; El-Agroudi, Mohammad A; Øgaard, Bjørn

    2012-10-01

    The aim of the study was to assess the effect of a comprehensive prophylactic regimen in reducing the incidence of white spot lesions (WSL) and caries during orthodontic treatment. Eighty consecutive patients, scheduled for fixed appliance treatment in both jaws were compared with a non-orthodontic matched-control group. The oral hygiene regimen consisted of brushing two to three times daily, flossing, fluoride rinse, and plaque disclosing tablets. Patients were requested to avoid carbonated soft drinks/acidic juices and candies. The WSL index of Gorelick et al. (Gorelick L, Geiger A M, Gwinnett A J 1982 Incidence of white spot formation after bonding and banding. American Journal of Orthodontics 81: 93-98) was used. Caries were scored according to Amarante et al. (Amarante E, Raadal M, Espelid I 1998 Impact of diagnostic criteria on the prevalence of dental caries in Norwegian children aged 5, 12 and 18 years. Community Dental Oral Epidemiology 26: 87-94). We collected data from all finished cases. It comprised 40 subjects in the orthodontic group (mean age: 13.6 years, range: 12-16 years) and 40 matched controls. The average treatment time was 18 months (range: 9-25 months). The mean increase in WSL index in the orthodontic group was 1.9 and 0.4 in the control group (P = 0.001). The mean increase in dentine caries was 0.5 lesions and 0.7 lesions in the in the orthodontic group and control group, respectively (P = 0.62). Twenty-three per cent of treated patients showed good compliance, 68 per cent moderate compliance, and 9 per cent poor compliance. The mean increase in WSL was 1.0, 1.4, and 3.3 in the good, moderate, and poor compliance group, respectively (P = 0.155). Orthodontically treated patients have significantly higher risk for developing WSL than untreated patients, while there is no difference with respect to development of new dentinal caries lesions. This study showed that a possible relationship between compliance and WSL development existed.

  16. Adolescent patient with bilateral crossbite treated with surgically assisted rapid maxillary expansion: a case report evaluated by the 3d laser scanner, and using FESA method.

    Science.gov (United States)

    Ivanov, Ch I; Velemínská, J; Dostálová, T; Foltán, R

    2011-01-01

    Our purpose in this case report is to present an orthodontic treatment obtained and the results achieved in 17-year-old white female patient with Angle Class II malocclusion and bilateral posterior crossbite. Patient was treated with bonded acrylic Hyrax appliance and surgically assisted rapid maxillary expansion (SARME). The multiloop system 0.16 TMA (ß titanium) arch wire was used in the alignment phase and on purpose to prohibit bite opening and optimize threedimensional movement control. After treatment bonded lingual retainers were placed in between maxillary central incisors and in mandible canine-to-canine. A functional removable Klammt appliance was used for retention. The 3D Laser Scanner Roland LPX-250 was used in order to obtain digital dental casts. Evaluation of the treatment results was measured on these models and using finite element scaling analysis (FESA). An Angle Class I relationship was obtained after 2½ years of treatment, function and facial aesthetics were improved. The shape of the palate changed significant in the width direction, not significantly in length and high direction. The greatest expansion of palate was found in the region between the palatal cusps of the first molars 26.6%, followed by first 21.9% and second premolars 16.5%. SARME in adult patients with bilateral cross bite and maxillary deficiency lead to satisfactory results. The 3D laser scanned models and their measurements, using advanced software's are successfully used for precise studies.

  17. One-Dimensional Horizontal Boussinesq Model Enhanced for Non-Breaking and Breaking Waves

    Institute of Scientific and Technical Information of China (English)

    DONG Guo-hai; MA Xiao-zhou; TENG Bin

    2008-01-01

    Based on a set of fully nonlinear Boussinesq equations up to the order of O(μ2, ε3μ2) (where ε is the ratio of wave amplitude to water depth and μ is the ratio of water depth to wave length) a numerical wave model is formulated. The model's linear dispersion is acceptably accurate to μ≌1.0, which is confirmed by comparisons between the simulated and measured time series of the regular waves propagating on a submerged bar. The moving shoreline is treated numerically by replacing the solid beach with a permeable beach. Run-up of nonbreaking waves is verified against the analytical solution for nonlinear shallow water waves. The inclusion of wave breaking is fulfilled by introducing an eddy term in the momentum equation to serve as the breaking wave force term to dissipate wave energy in the surf zone. The model is applied to cross-shore motions of regular waves including various types of breaking on plane sloping beaches. Comparisons of the model test results comprising spatial distribution of wave height and mean water level with experimental data are presented.

  18. Developmental hip dysplasia in adolescence

    Directory of Open Access Journals (Sweden)

    Vukašinović Zoran

    2009-01-01

    Full Text Available The authors define adolescence and developmental dysplasia of the hip (DDH. Special attention is paid to pathological findings characteristic of DDH in adolescence (unrecognized and untreated DDH; treated DDH, but non-terminated treatment; DDH diagnosed with delay, inadequately treated, with complications. The authors emphasise that DDH treatment has to be successfully terminated well before the adolescence; possibilities are explained on management modes at the time of adolescence, and possible persons guilty for the persistence of later hip problems are indicated. Based on the authors' experience and having in mind all surgical possibilities for the treatment (pelvic osteotomies, femoral osteotomies, trochanteroplasties, leg length equalization procedures the authors propose treatment protocols. The intention is to provide better treatment results and to prevent secondary hip arthrosis. Furthermore, how to improve the struggle against DDH is suggested.

  19. Retinal breaks due to intravitreal ocriplasmin

    Directory of Open Access Journals (Sweden)

    Silva RA

    2014-08-01

    Full Text Available Ruwan A Silva, Darius M Moshfeghi, Theodore Leng Byers Eye Institute at Stanford, Stanford University School of Medicine, Palo Alto, CA, USA Abstract: Ocriplasmin represents a new treatment option for numerous vitreoretinopathies involving an abnormal vitreomacular interface. While the drug may circumvent the traditional risks of surgical treatment, pharmacologic vitreolysis is not devoid of risk itself. This report presents two cases, one of vitreomacular traction syndrome and the other of a full-thickness macular hole, both of which were treated with an intravitreal injection of ocriplasmin. Notably, in both cases, vitreomacular traction of the macula appears to have been alleviated; however, failure to completely relieve vitreoretinal traction from the peripheral retina generated retinal breaks with one patient eventually developing a macula-involving retinal detachment. Thus, even in instances of ‘successful’ pharmacologic treatment of vitreomacular traction, continued follow-up evaluation is essential. Keywords: posterior vitreous detachment, retinal detachment, vitreomacular traction, ocriplasmin, retinal break, macular hole, laser retinopexy

  20. An Analysis of Break,Break,Break Based on the Stylistic Theory

    Institute of Scientific and Technical Information of China (English)

    李瑶

    2014-01-01

    Break,Break,Break is a poem by Alfred Lord Tennyson, the Poet Laureate during the Queen Victoria's reign. This exquisite little poem is wel known for the poet’s grief-stricken feelings and heart-broken emotions over the premature death of his best friend, Arthur Henry Hal am. Most of the previous studies on this poem focus on the emotional level to consider it as an elegy, expressing sorrow and lamentation for the death of a particular person. However, in order to have a deep understanding in general, this paper analyzes the poem based on the stylistic theory, concerning on the phonological level and the grammatical level. It aims at helping the readers to cultivate a sense of appropriateness, to sharpen the understanding and appreciation of literary works and to achieve adaptation in translation.

  1. Adolescent Idiopathic Scoliosis

    Directory of Open Access Journals (Sweden)

    Safak Ekinci

    2014-06-01

    Full Text Available Scoliosis is called idiopathic when no other underlying disease can be identified. The etiology of adolescent idiopathic scoliosis (AIS is still unknown despite many years of research effort. Theories on AIS's etiology have included mechanical, hormonal, metabolic, neuromuscular, growth, and genetic abnormalities. Skeletally immature patients with adolescent idiopathic scoliosis are at risk of curve progression. The adolescent onset of severe idiopathic scoliosis has traditionally been evaluated using standing posteroanterior radiographs of the full spine to assess lateral curvature with the Cobb method. Scoliosis in children of school age and above primarily occurs in girls. The therapeutic goal in children is to prevent progression. In children, scoliosis of 20 and deg; or more should be treated with a brace, and scoliosis of 45 and deg; or more with surgery. [Arch Clin Exp Surg 2014; 3(3.000: 174-182

  2. Hole localization and symmetry breaking

    NARCIS (Netherlands)

    Broer, R; Nieuwpoort, W.C.

    1999-01-01

    A brief overview is presented of some theoretical work on the symmetry breaking of electronic wavefunctions that followed the early work on Bagus and Schaefer who observed that a considerable lower SCF energy could be obtained for an ionized state of the O2 molecule with a 1s hole if the symmetry re

  3. Appointment breaking: causes and solutions.

    Science.gov (United States)

    Bean, A G; Talaga, J

    1992-12-01

    From a review of research on health care appointment breaking, the authors find that patient demographic characteristics, psychosocial problems, previous appointment keeping, health beliefs, and situational factors predict no-show behavior. Suggestions are offered for designing the marketing mix to increase patient appointment keeping. Methods for mitigating the negative effects of no-shows on health care providers are described.

  4. Code breaking in the pacific

    CERN Document Server

    Donovan, Peter

    2014-01-01

    Covers the historical context and the evolution of the technically complex Allied Signals Intelligence (Sigint) activity against Japan from 1920 to 1945 Describes, explains and analyzes the code breaking techniques developed during the war in the Pacific Exposes the blunders (in code construction and use) made by the Japanese Navy that led to significant US Naval victories

  5. Inflationary implications of supersymmetry breaking

    NARCIS (Netherlands)

    Borghese, Andrea; Roest, Diederik; Zavala, Ivonne

    2013-01-01

    We discuss a general bound on the possibility to realise inflation in any minimal supergravity with F-terms. The derivation crucially depends on the sGoldstini, the scalar field directions that are singled out by spontaneous supersymmetry breaking. The resulting bound involves both slow-roll paramet

  6. Breaking Carbon Lock-in

    DEFF Research Database (Denmark)

    Driscoll, Patrick Arthur

    2014-01-01

    This central focus of this paper is to highlight the ways in which path dependencies and increasing returns (network effects) serve to reinforce carbon lock-in in large-scale road transportation infrastructure projects. Breaking carbon lock-in requires drastic changes in the way we plan future...

  7. Strong coupling electroweak symmetry breaking

    Energy Technology Data Exchange (ETDEWEB)

    Barklow, T.L. [Stanford Linear Accelerator Center, Menlo Park, CA (United States); Burdman, G. [Univ. of Wisconsin, Madison, WI (United States). Dept. of Physics; Chivukula, R.S. [Boston Univ., MA (United States). Dept. of Physics

    1997-04-01

    The authors review models of electroweak symmetry breaking due to new strong interactions at the TeV energy scale and discuss the prospects for their experimental tests. They emphasize the direct observation of the new interactions through high-energy scattering of vector bosons. They also discuss indirect probes of the new interactions and exotic particles predicted by specific theoretical models.

  8. Small Break Air Ingress Experiment

    Energy Technology Data Exchange (ETDEWEB)

    Chang Oh; Eung Soo Kim

    2011-09-01

    The small break air-ingress experiment, described in this report, is designed to investigate air-ingress phenomena postulated to occur in pipes in a very high temperature gas-cooled reactor (VHTRs). During this experiment, air-ingress rates were measured for various flow and break conditions through small holes drilled into a pipe of the experimental apparatus. The holes were drilled at right angles to the pipe wall such that a direction vector drawn from the pipe centerline to the center of each hole was at right angles with respect to the pipe centerline. Thus the orientation of each hole was obtained by measuring the included angle between the direction vector of each hole with respect to a reference line anchored on the pipe centerline and pointing in the direction of the gravitational force. Using this reference system, the influence of several important parameters on the air ingress flow rate were measured including break orientation, break size, and flow velocity . The approach used to study the influence of these parameters on air ingress is based on measuring the changes in oxygen concentrations at various locations in the helium flow circulation system as a function of time using oxygen sensors (or detectors) to estimate the air-ingress rates through the holes. The test-section is constructed of a stainless steel pipe which had small holes drilled at the desired locations.

  9. Aluminum break-point contacts

    NARCIS (Netherlands)

    Heinemann, Martina; Groot, R.A. de

    1997-01-01

    Ab initio molecular dynamics is used to study the contribution of a single Al atom to an aluminum breakpoint contact during the final stages of breaking and the initial stages of the formation of such a contact. A hysteresis effect is found in excellent agreement with experiment and the form of the

  10. How do accretion discs break?

    Science.gov (United States)

    Dogan, Suzan

    2016-07-01

    Accretion discs are common in binary systems, and they are often found to be misaligned with respect to the binary orbit. The gravitational torque from a companion induces nodal precession in misaligned disc orbits. In this study, we first calculate whether this precession is strong enough to overcome the internal disc torques communicating angular momentum. We compare the disc precession torque with the disc viscous torque to determine whether the disc should warp or break. For typical parameters precession wins: the disc breaks into distinct planes that precess effectively independently. To check our analytical findings, we perform 3D hydrodynamical numerical simulations using the PHANTOM smoothed particle hydrodynamics code, and confirm that disc breaking is widespread and enhances accretion on to the central object. For some inclinations, the disc goes through strong Kozai cycles. Disc breaking promotes markedly enhanced and variable accretion and potentially produces high-energy particles or radiation through shocks. This would have significant implications for all binary systems: e.g. accretion outbursts in X-ray binaries and fuelling supermassive black hole (SMBH) binaries. The behaviour we have discussed in this work is relevant to a variety of astrophysical systems, for example X-ray binaries, where the disc plane may be tilted by radiation warping, SMBH binaries, where accretion of misaligned gas can create effectively random inclinations and protostellar binaries, where a disc may be misaligned by a variety of effects such as binary capture/exchange, accretion after binary formation.

  11. Mother-Adolescent Health Communication: Are All Conversations Created Equally?

    Science.gov (United States)

    Boone, Tanya L.; Lefkowitz, Eva S.

    2007-01-01

    Fifty-two mother-adolescent dyads (mean adolescent age = 16.3) participated in an observational study of communication about health topics. The aim of the study was to examine mother-adolescent conversations about health issues--drugs/alcohol, sexuality, nutrition/exercise--to determine the extent to which the mothers treat these issues similarly.…

  12. O8.07HISTOLOGY, LOCALISATION, TREATMENT AND OUTCOME OF 339 CONSECUTIVE CHILDREN AND ADOLESCENTS WITH LOW GRADE GLIOMAS TREATED AT THE MEDICAL UNIVERSITY OF VIENNA BETWEEN 1993 AND 2012

    Science.gov (United States)

    Slavc, I.; Chocholous, M.; Woehrer, A.; Heumesser, R.; Azizi, A.; Haberler, C.; Peyrl, A.; Dorfer, C.; Dieckmann, K.; Czech, T.

    2014-01-01

    Low grade gliomas (LGG) comprise a spectrum of different tumor entities corresponding to WHO grade I and II, including pilocytic astrocytoma, diffuse glioma and glioneuronal tumors. LGG in children differ in histologic distribution, molecular profile, localisation in the CNS and outcome from LGGs in adults. We report on a series of patients treated at a single center over 20 years. PATIENTS: Between 1993 and 2012, 339 consecutive patients with a median age of 8 years (range 4 months - 18 years, p25 = 3.7 years, p75 = 13.4 years) were treated at the Medical University of Vienna. 19.5% of the patients were <3 years of age at diagnosis. Gender distribution was equal. Tumors were associated with syndromes in 84 of the patients (NF1: n = 64, TSC: n = 17, and other: n = 3). Localisation was supratentorial midline in 112, cerebral hemispheres in 105, posterior fossa in 86, ventricular system in 27 and spinal in 9 patients. 66 patients with a median age of 4.4 years had optic pathway gliomas. RESULTS: Gross total resection was performed in 109, subtotal resection in 49, partial resection in 57, and biopsy in 22 patients. 83 patients had no surgery (patients with NF1, TSC, tectal glioma or tumors confined to the optic nerves and chiasm), and in the remaining the degree of resection was not evaluable. 37 patients had 2 tumor surgeries, 14 three, 5 four and one had 5 tumor surgeries during their course of disease. Histology was pilocytic astrocytoma in 122, pilomyxoid astrocytoma in 10, diffuse astrocytoma in 42, ganglioglioma in 30, subependymal giant cell astrocytoma in 17, oligoastrocytoma in 11, and other rarer histologies in the remaining patients. Twelve patients (3.5%) died and 84 patients (24.8%) had at least one event. After a median follow-up of 107 months (14-300) the 1-year overall survival (OS) was 100%, the 10-year OS 96.1 ± 1.2%, and the 20-year OS 95.3 ± 1.4%. Event-free survival (EFS) after 1 year was 92.9 ± 1.4%, after 10 years 73.8 ± 2.6% and after 20

  13. Breaking Wave Characteristics and Breaking Wave Forces on Slender Cylinders

    OpenAIRE

    Chella, Mayilvahanan Alagan

    2016-01-01

    Offshore wind farms have become an increasingly important source of clean and renewable energy. Most recent offshore wind farms are deployed close to the coast in shallow waters. One of the major factors influencing the initial investment of this technology is the design of the substructure and foundation. The physical processes associated with the non-linear shallow water hydrodynamics are rather complex since the wave motion is strongly influenced by the seabed. Breaking wave...

  14. A model of intrinsic symmetry breaking

    Energy Technology Data Exchange (ETDEWEB)

    Ge, Li [Research Center for Quantum Manipulation, Department of Physics, Fudan University, Shanghai 200433 (China); Li, Sheng [Department of Physics, Zhejiang Normal University, Zhejiang 310004 (China); George, Thomas F., E-mail: tfgeorge@umsl.edu [Office of the Chancellor and Center for Nanoscience, Department of Chemistry and Biochemistry, University of Missouri-St. Louis, St. Louis, MO 63121 (United States); Department of Physics and Astronomy, University of Missouri-St. Louis, St. Louis, MO 63121 (United States); Sun, Xin, E-mail: xin_sun@fudan.edu.cn [Research Center for Quantum Manipulation, Department of Physics, Fudan University, Shanghai 200433 (China)

    2013-11-01

    Different from the symmetry breaking associated with a phase transition, which occurs when the controlling parameter is manipulated across a critical point, the symmetry breaking presented in this Letter does not need parameter manipulation. Instead, the system itself suddenly undergoes symmetry breaking at a certain time during its evolution, which is intrinsic symmetry breaking. Through a polymer model, it is revealed that the origin of the intrinsic symmetry breaking is nonlinearity, which produces instability at the instance when the evolution crosses an inflexion point, where this instability breaks the original symmetry.

  15. Homosexuality, Counseling, and the Adolescent Male

    Science.gov (United States)

    Kremer, Ellen R.; And Others

    1975-01-01

    Authors report relatively high incidence of homosexuality among adolescents. They review various attitudes, theories and methods to treat homosexuality. Counselor should be aware of his/her own attitudes and reactions towards homosexuality and should be ready to discuss it in a direct, nonthreatened and open manner with adolescents and other…

  16. Parent-Adolescent Conflict: An Empirical Review.

    Science.gov (United States)

    Hall, James A.

    1987-01-01

    Compares psychoanalytic, systems, and social learning theories to determine the empirical support for each theoretical orientation in treating problematic conflict between parents and adolescents. Discusses parent-adolescent conflict, including developmental stage theory, parenting styles, peer pressures, communication skills, marital conflict,…

  17. 功能锻炼配合推拿治疗青少年颈椎病40例疗效分析%Efficacy analysis on treating 80 cases of adolescent cervical spondylosis with functional exercise combined with massage therapy

    Institute of Scientific and Technical Information of China (English)

    贺春明

    2013-01-01

      目的:观察功能锻炼联合推拿治疗青少年颈椎病的疗效.方法:选择80例青少年颈椎病随机分为两组,对照组给予推拿治疗,实验组给予功能锻炼联合推拿,对比疗效.结果:实验组疗效优于对照组,P<0.05.结论:采用功能锻炼联合推拿治疗青少年颈椎病的效果较好,值得临床推广应用.%Objective: To observe the efficacy of treating adolescent cervical spondylosis with functional exercise combined with massage therapy. Methods: 80 patients with adolescent cervical spondylosis were randomly divided into two groups. The control group was given massage therapy, while the experimental group was given functional exercise more. The efficacies in both groups were compared. Results: The efficacy in the experimental group was significantly better than that in the control group (P<0.05). Conclusion: The functional exercise combined with massage therapy was effective in treating adolescent cervical spondylosis, worth a wide clinical application.

  18. Symmetries, Symmetry Breaking, Gauge Symmetries

    CERN Document Server

    Strocchi, Franco

    2015-01-01

    The concepts of symmetry, symmetry breaking and gauge symmetries are discussed, their operational meaning being displayed by the observables {\\em and} the (physical) states. For infinitely extended systems the states fall into physically disjoint {\\em phases} characterized by their behavior at infinity or boundary conditions, encoded in the ground state, which provide the cause of symmetry breaking without contradicting Curie Principle. Global gauge symmetries, not seen by the observables, are nevertheless displayed by detectable properties of the states (superselected quantum numbers and parastatistics). Local gauge symmetries are not seen also by the physical states; they appear only in non-positive representations of field algebras. Their role at the Lagrangian level is merely to ensure the validity on the physical states of local Gauss laws, obeyed by the currents which generate the corresponding global gauge symmetries; they are responsible for most distinctive physical properties of gauge quantum field ...

  19. On Anomaly Mediated SUSY Breaking

    CERN Document Server

    de Alwis, S P

    2008-01-01

    A discrepancy between the Anomaly Mediated Supersymmetry Breaking (AMSB) gaugino mass calculated from the work of Kaplunovsky and Louis (hep-th/9402005) (KL) and other calculations in the literature is explained, and it is argued that the KL expression is the correct one relevant to the Wilsonian action. Furthermore it is argued that the AMSB contribution to the squark and slepton masses should be replaced by the contribution pointed out by Dine and Seiberg (DS) which has nothing to do with Weyl anomalies. This is not in general equivalent to the AMSB expression, and it is shown that there are models in which the usual AMSB expression would vanish but the DS one is non-zero. In fact the latter has aspects of both AMSB and gauge mediated SUSY breaking. In particular like the latter, it gives positive squared masses for sleptons.

  20. Renormalizable theories with symmetry breaking

    CERN Document Server

    Becchi, Carlo M

    2016-01-01

    The description of symmetry breaking proposed by K. Symanzik within the framework of renormalizable theories is generalized from the geometrical point of view. For an arbitrary compact Lie group, a soft breaking of arbitrary covariance, and an arbitrary field multiplet, the expected integrated Ward identities are shown to hold to all orders of renormalized perturbation theory provided the Lagrangian is suitably chosen. The corresponding local Ward identity which provides the Lagrangian version of current algebra through the coupling to an external, classical, Yang-Mills field, is then proved to hold up to the classical Adler-Bardeen anomaly whose general form is written down. The BPHZ renormalization scheme is used throughout in such a way that the algebraic structure analyzed in the present context may serve as an introduction to the study of fully quantized gauge theories.

  1. Breaking through the tranfer tunnel

    CERN Multimedia

    Laurent Guiraud

    2001-01-01

    This image shows the tunnel boring machine breaking through the transfer tunnel into the LHC tunnel. Proton beams will be transferred from the SPS pre-accelerator to the LHC at 450 GeV through two specially constructed transfer tunnels. From left to right: LHC Project Director, Lyn Evans; CERN Director-General (at the time), Luciano Maiani, and Director for Accelerators, Kurt Hubner.

  2. Explaining quantum spontaneous symmetry breaking

    Science.gov (United States)

    Liu, Chuang; Emch, Gérard G.

    Two accounts of quantum symmetry breaking (SSB) in the algebraic approach are compared: the representational and the decompositional account. The latter account is argued to be superior for understanding quantum SSB. Two exactly solvable models are given as applications of our account: the Weiss-Heisenberg model for ferromagnetism and the BCS model for superconductivity. Finally, the decompositional account is shown to be more conducive to the causal explanation of quantum SSB.

  3. Literary Careers: Breaks and Stalls

    OpenAIRE

    Crozier, W. Ray

    2001-01-01

    In his article, "Literary Careers: Breaks and Stalls," W. Ray Crozier argues that biographical evidence points to considerable individual variation in writers' output over the life span even when allowance is made for longevity and length of writing career. This issue has been neglected by psychological accounts of creativity. Crozier outlines a theoretical framework for understanding variation in terms of an "artistic career." This is conceptualised as a sequence of projects, the success of ...

  4. Using Music Techniques To Treat Adolescent Depression.

    Science.gov (United States)

    Hendricks, C. Bret; Robinson, Beth; Bradley, Loretta J.; Davis, Kenneth

    1999-01-01

    Discusses a school-based therapy program using music for teenagers (N=19) who demonstrated depressive symptoms. Pre- and post-testing indicated a significant decrease in depressive symptoms. Offers recommendations for further research. (Author/MKA)

  5. On the Translating Styles of Two Chinese Versions in Break, Break, Break%评Break,Break,Break两种译文的翻译风格

    Institute of Scientific and Technical Information of China (English)

    许颖红

    2011-01-01

    美国著名翻译家提莫志克指出,翻译就其本质而言只能是一部分翻译,忠实地再现原文所有的信息根本不可能,诗歌的准确翻译就更不容易了。对丁尼生的一首短诗的两种译文进行评析,希望通过分析能对此诗有更深刻的理解。%Tymocko, famous American translator, points out that translation is actually only the translation of part of the language because it is impossible to reproduce all the messages. It is even more difiqeuh to translate a poem. For profound understanding, this paper contrasts two Chinese versions of Break, Break, Break, a short poem of Tennyson.

  6. Accessibility of adolescent health services

    Directory of Open Access Journals (Sweden)

    S Richter

    2000-09-01

    Full Text Available Adolescents represent a large proportion of the population. As they mature and become sexually active, they face more serious health risks. Most face these risks with too little factual information, too little guidance about sexual responsibility and multiple barriers to accessing health care. A typical descriptive and explanatory design was used to determine what the characteristics of an accessible adolescent health service should be. Important results and conclusions that were reached indicate that the adolescent want a medical doctor and a registered nurse to be part of the health team treating them and they want to be served in the language of their choice. Family planning, treatment of sexually transmitted diseases and psychiatric services for the prevention of suicide are services that should be included in an adolescent accessible health service. The provision of health education concerning sexual transmitted diseases and AIDS is a necessity. The service should be available thought out the week (included Saturdays and within easy reach. It is recommended that minor changes in existing services be made, that will contribute towards making a health delivery service an adolescent accessible service. An adolescent accessible health service can in turn make a real contribution to the community’s efforts to improve the health of its adolescents and can prove to be a rewarding professional experience to the health worker.

  7. Adolescent Loneliness.

    Science.gov (United States)

    Goldenberg, Sheila

    Research has suggested that the incidence of loneliness peaks at adolescence and decreases with age. Changes in the determinants of loneliness during adolescence were investigated for grade 8, grade 11, and university students. Subjects (N=410) completed a written questionnaire which included ten items from the UCLA Loneliness Scale, the…

  8. Positively Adolescent!

    Science.gov (United States)

    Williamson, Sue

    2000-01-01

    Believes that music teachers should reassess their views toward adolescent behavior in the music classroom by learning to see their behavior in a positive light. Describes teaching strategies that build on four adolescent behaviors: (1) desire for peer acceptance; (2) abundant energy; (3) love of fun; and (4) limited time-managing skills. (CMK)

  9. Punishing adolescents

    DEFF Research Database (Denmark)

    Ryberg, Jesper

    2014-01-01

    Should an adolescent offender be punished more leniently than an adult offender? Many theorists believe the answer to be in the affirmative. According to the diminished culpability model, adolescents are less mature than adults and, therefore, less responsible for their wrongdoings and should...

  10. Leaders break ground for INFINITY

    Science.gov (United States)

    2008-01-01

    Community leaders from Mississippi and Louisiana break ground for the new INFINITY at NASA Stennis Space Center facility during a Nov. 20 ceremony. Groundbreaking participants included (l to r): Gottfried Construction representative John Smith, Mississippi Highway Commissioner Wayne Brown, INFINITY board member and Apollo 13 astronaut Fred Haise, Stennis Director Gene Goldman, Studio South representative David Hardy, Leo Seal Jr. family representative Virginia Wagner, Hancock Bank President George Schloegel, Mississippi Rep. J.P. Compretta, Mississippi Band of Choctaw Indians representative Charlie Benn and Louisiana Sen. A.G. Crowe.

  11. History of electroweak symmetry breaking

    CERN Document Server

    Kibble, T W B

    2015-01-01

    In this talk, I recall the history of the development of the unified electroweak theory, incorporating the symmetry-breaking Higgs mechanism, as I saw it from my standpoint as a member of Abdus Salam's group at Imperial College. I start by describing the state of physics in the years after the Second World War, explain how the goal of a unified gauge theory of weak and electromagnetic interactions emerged, the obstacles encountered, in particular the Goldstone theorem, and how they were overcome, followed by a brief account of more recent history, culminating in the historic discovery of the Higgs boson in 2012.

  12. Treatment Options for Primary Refractory/Recurrent Hodgkin Lymphoma in Children and Adolescents

    Science.gov (United States)

    ... Primary Refractory/Recurrent Hodgkin Lymphoma in Children and Adolescents Primary refractory Hodgkin lymphoma is lymphoma that continues ... treated with an adult treatment regimen . Children and adolescents may have treatment-related side effects that appear ...

  13. Introduction to Electroweak Symmetry Breaking

    Energy Technology Data Exchange (ETDEWEB)

    Dawson,S.

    2008-10-02

    The Standard Model (SM) is the backbone of elementary particle physics-not only does it provide a consistent framework for studying the interactions of quark and leptons, but it also gives predictions which have been extensively tested experimentally. In these notes, I review the electroweak sector of the Standard Model, discuss the calculation of electroweak radiative corrections to observables, and summarize the status of SM Higgs boson searches. Despite the impressive experimental successes, however, the electroweak theory is not completely satisfactory and the mechanism of electroweak symmetry breaking is untested. I will discuss the logic behind the oft-repeated statement: 'There must be new physics at the TeV scale'. These lectures reflect my strongly held belief that upcoming results from the LHC will fundamentally change our understanding of electroweak symmetry breaking. In these lectures, I review the status of the electroweak sector of the Standard Model, with an emphasis on the importance of radiative corrections and searches for the Standard Model Higgs boson. A discussion of the special role of the TeV energy scale in electroweak physics is included.

  14. Chiral symmetry breaking and monopoles

    CERN Document Server

    Di Giacomo, Adriano; Pucci, Fabrizio

    2015-01-01

    To understand the relation between the chiral symmetry breaking and monopoles, the chiral condensate which is the order parameter of the chiral symmetry breaking is calculated in the $\\overline{\\mbox{MS}}$ scheme at 2 [GeV]. First, we add one pair of monopoles, varying the monopole charges $m_{c}$ from zero to four, to SU(3) quenched configurations by a monopole creation operator. The low-lying eigenvalues of the Overlap Dirac operator are computed from the gauge links of the normal configurations and the configurations with additional monopoles. Next, we compare the distributions of the nearest-neighbor spacing of the low-lying eigenvalues with the prediction of the random matrix theory. The low-lying eigenvalues not depending on the scale parameter $\\Sigma$ are compared to the prediction of the random matrix theory. The results show the consistency with the random matrix theory. Thus, the additional monopoles do not affect the low-lying eigenvalues. Moreover, we discover that the additional monopoles increa...

  15. How often precipitation records break?

    Science.gov (United States)

    Papalexiou, Simon Michael; Oikonomou, Maria; Floutsakou, Athina; Bessas, Nikolaos; Mamassis, Nikos

    2016-04-01

    How often precipitation records break? Are there any factors that determine the average time needed for the next maximum to occur? In order to investigate these simple questions we use several hundreds of daily precipitation records (more than 100 years long each) and we study the time intervals between each successive maximum precipitation value. We investigate if the record breaking time interval is related (a) to the autocorrelation structure, (b) to probability dry, and (c) to the tail of the marginal distribution. For the last, we first, evaluate which type of tail is better fitted by choosing among three general types of tails corresponding to the distributions Pareto, Lognormal and Weibull; and second, we assess the heaviness of the tail based on the estimated shape parameter. The performance of each tail is evaluated in terms of return period values, i.e., we compare the empirical return periods of precipitation values above a threshold with the predicted ones by each of the three types of fitted tails.

  16. Boundary breaking for interdisciplinary learning

    Directory of Open Access Journals (Sweden)

    Adi Kidron

    2015-10-01

    Full Text Available The purpose of this work is to contribute to the body of knowledge on processesby which students develop interdisciplinary understanding of contents, as well as to suggest technology-enhanced means for supporting them in these processes in the context of higher education. In doing so, we suggest a rethinking of three traditional practices that tend to characterise typical higher education instruction: (1 compartmentalisation of disciplines; (2 traditional pedagogy; and (3 traditional hierarchies based on levels of expertise. Our high-level conjecture was that meaningful dialogue with peers and experts supports both the deepening of ideas in one knowledge domain and the formation of connections between ideas from several domains, both of which are required for the development of interdisciplinary understanding. We developed the Boundary Breaking for Interdisciplinary Learning (BBIL model, which harnesses technology to break boundaries between disciplines, learners and organisational levels of hierarchy. Findings indicate that 36 undergraduate students who participated in an interdisciplinary online course that implemented the BBIL model have significantly improved their interdisciplinary understanding of the course contents. This study illustrates how innovative use of available, free and low-cost technology can produce a ‘positive disruption’ in higher education instruction.

  17. Improved single sector supersymmetry breaking

    Energy Technology Data Exchange (ETDEWEB)

    Luty, Markus A.; Terning, John

    1998-12-09

    Building on recent work by N. Arkani-Hamed and the present authors, we construct realistic models that break supersymmetry dynamically and give rise to composite quarks and leptons, all in a single strongly-coupled sector. The most important improvement compared to earlier models is that the second-generation composite states correspond to dimension-2 ''meson'' operators in the ultraviolet. This leads to a higher scale for flavor physics, and gives a completely natural suppression of flavor-changing neutral currents. We also construct models in which the hierarchy of Yukawa couplings is explained by the dimensionality of composite states. These models provide an interesting and viable alternative to gravity- and gauge-mediated models. The generic signatures are unification of scalar masses with different quantum numbers at the compositeness scale, and lighter gaugino, Higgsino, and third-generation squark and slepton masses. We also analyze large classes of models that give rise to both compositeness and supersymmetry breaking, based on gauge theories with confining, fixed-point, or free-magnetic dynamics.

  18. Stages of Adolescence

    Science.gov (United States)

    ... Español Text Size Email Print Share Stages of Adolescence Page Content Article Body Adolescence, these years from puberty to adulthood, may be roughly divided into three stages: early adolescence, generally ages eleven to fourteen; middle adolescence, ages ...

  19. Socially induced morphine pseudosensitization in adolescent mice.

    Science.gov (United States)

    Hodgson, Stephen R; Hofford, Rebecca S; Roberts, Kris W; Wellman, Paul J; Eitan, Shoshana

    2010-03-01

    Given that social influences are among the strongest predictors of adolescents' drug use, this study examined the effect of social interaction on morphine-induced hyperlocomotion in both adolescent and adult mice. Three experimental groups of adolescent and adult male mice were examined (i) morphine-treated mice (twice daily, 10-40 mg/kg, subcutaneous), (ii) saline-injected mice housed together with the morphine-treated mice ('saline cage-mates'), and (iii) saline-injected mice housed physically and visually separated from the morphine-treated mice ('saline alone'). After the treatment period, mice were tested individually for their locomotor response to 10 mg/kg morphine (subcutaneous). Adolescent saline cage-mates, though administered morphine for the very first time, exhibited an enhanced hyperlocomotion response similar to the locomotor sensitization response exhibited by the morphine-treated mice. This was not observed in adults. In adults, there were no significant differences in morphine-induced hyperlocomotion between saline alone and saline cage-mates. As expected, morphine-treated adults and adolescents both exhibited locomotor sensitization. These results show a vulnerability to social influences in adolescent mice, which does not exist in adult mice.

  20. Sediment transport under breaking waves

    DEFF Research Database (Denmark)

    Christensen, Erik Damgaard; Hjelmager Jensen, Jacob; Mayer, Stefan

    2000-01-01

    The sediment transport in the surf zone is modelled by combining a Navier-Stokes solver, a free surface model, a turbulence model, and a sediment transport model. The flow solver is based on the finite volume technique for non-orthogonal grids. The model is capable of simulating the turbulence...... generated at the surface where the wave breaks as well as the turbulence generated near the bed due to the wave-motion and the undertow. In general, the levels of turbulent kinetic energy are found to be higher than experiments show. This results in an over prediction of the sediment transport. Nevertheless......, some qualitative features have been modelled with success such as the onshore transport under plunging breakers and offshore transport under spilling breakers....

  1. Dynamical centrosymmetry breaking in graphene

    CERN Document Server

    Carvalho, David N; Biancalana, Fabio

    2016-01-01

    We discover an unusual phenomenon that occurs when a graphene monolayer is illuminated by a short and intense pulse at normal incidence. Due to the pulse-induced oscillations of the Dirac cones, a dynamical breaking of the layer's centrosymmetry takes place, leading to the generation of second harmonic waves. We prove that this result can only be found by using the full Dirac equation and show that the widely used semiconductor Bloch equations fail to reproduce this and some other important physics of graphene. Our results open new windows in the understanding of nonlinear light-matter interactions in a wide variety of new 2D materials with a gapped or ungapped Dirac-like dispersion.

  2. Electroweak symmetry breaking via QCD.

    Science.gov (United States)

    Kubo, Jisuke; Lim, Kher Sham; Lindner, Manfred

    2014-08-29

    We propose a new mechanism to generate the electroweak scale within the framework of QCD, which is extended to include conformally invariant scalar degrees of freedom belonging to a larger irreducible representation of SU(3)c. The electroweak symmetry breaking is triggered dynamically via the Higgs portal by the condensation of the colored scalar field around 1 TeV. The mass of the colored boson is restricted to be 350  GeV≲mS≲3  TeV, with the upper bound obtained from perturbative renormalization group evolution. This implies that the colored boson can be produced at the LHC. If the colored boson is electrically charged, the branching fraction of the Higgs boson decaying into two photons can slightly increase, and moreover, it can be produced at future linear colliders. Our idea of nonperturbative electroweak scale generation can serve as a new starting point for more realistic model building in solving the hierarchy problem.

  3. Gedanken Worlds without Higgs: QCD-Induced Electroweak Symmetry Breaking

    Energy Technology Data Exchange (ETDEWEB)

    Quigg, Chris; /Fermilab /Karlsruhe U., TTP; Shrock, Robert; /YITP, Stony Brook

    2009-01-01

    To illuminate how electroweak symmetry breaking shapes the physical world, we investigate toy models in which no Higgs fields or other constructs are introduced to induce spontaneous symmetry breaking. Two models incorporate the standard SU(3){sub c} {circle_times} SU(2){sub L} {circle_times} U(1){sub Y} gauge symmetry and fermion content similar to that of the standard model. The first class--like the standard electroweak theory--contains no bare mass terms, so the spontaneous breaking of chiral symmetry within quantum chromodynamics is the only source of electroweak symmetry breaking. The second class adds bare fermion masses sufficiently small that QCD remains the dominant source of electroweak symmetry breaking and the model can serve as a well-behaved low-energy effective field theory to energies somewhat above the hadronic scale. A third class of models is based on the left-right-symmetric SU(3){sub c} {circle_times} SU(2){sub L} {circle_times} SU(2){sub R} {circle_times} U(1)B?L gauge group. In a fourth class of models, built on SU(4){sub PS} {circle_times} SU(2){sub L} {circle_times} SU(2){sub R} gauge symmetry, lepton number is treated as a fourth color. Many interesting characteristics of the models stem from the fact that the effective strength of the weak interactions is much closer to that of the residual strong interactions than in the real world. The Higgs-free models not only provide informative contrasts to the real world, but also lead us to consider intriguing issues in the application of field theory to the real world.

  4. Gravity with background fields and diffeomorphism breaking

    CERN Document Server

    Bluhm, Robert

    2016-01-01

    Effective gravitational field theories with background fields break local Lorentz symmetry and diffeomorphism invariance. Examples include Chern-Simons gravity, massive gravity, and the Standard-Model Extension (SME). The physical properties and behavior of these theories depend greatly on whether the spacetime symmetry breaking is explicit or spontaneous. With explicit breaking, the background fields are fixed and nondynamical, and the resulting theories are fundamentally different from Einstein's General Relativity (GR). However, when the symmetry breaking is spontaneous, the background fields are dynamical in origin, and many of the usual features of Einstein's GR still apply.

  5. Linhas escleróticas metafisárias em crianças e adolescentes em uso de alendronato Sclerotic metaphyseal lines in children and adolescents treated with alendronate

    Directory of Open Access Journals (Sweden)

    Érika C.C. Silva

    2010-06-01

    Full Text Available INTRODUÇÃO: Os bisfosfonatos inibem a reabsorção óssea pela interferência na ação dos osteoclastos. Dentre os efeitos adversos, as linhas escleróticas em metáfise de ossos longos são descritas como principal alteração radiográfica na faixa etária pediátrica. OBJETIVO: Avaliar a frequência de alterações radiográficas causadas pelo alendronato utilizado em crianças e adolescentes com baixa densidade óssea ou calcinose. PACIENTES E MÉTODOS: Foi realizado um estudo do tipo coorte retrospectiva analisando-se prontuários de 21 pacientes que fizeram uso de alendronato semanal por no mínimo 10 meses. Os pacientes realizaram radiografias de ossos longos antes do início do alendronato e aproximadamente um ano após o seu uso. RESULTADOS: Onze pacientes (52,3% apresentaram linhas escleróticas em metáfise dos ossos longos. A localização mais frequente foi em tíbia (8/11 pacientes, seguida de fêmur (7/11, úmero (6/11, rádio (4/11, ulna (3/11 e fíbula (2/11. Nenhum paciente apresentou regress��o das alterações radiográficas durante o tempo de evolução (até 1,1 ano após a suspensão do alendronato. CONCLUSÃO: Se usado com critério, o alendronato é seguro e as alterações radiográficas não mostraram ter um significado mais importante.INTRODUCTION: Bisphosphonates inhibit bone resorption by interfering with the action of osteoclasts. Among the adverse effects, sclerotic lines observed in the metaphysis of long bones have been described as the main imaging finding in pediatric patients. OBJECTIVE: To evaluate the frequency of radiographic changes caused by alendronate in children and adolescents with low bone density or calcinosis. PATIENTS AND METHODS: We conducted a cross-sectional study with 21 patients who were treated with once-weekly alendronate for at least 10 months. Patients underwent x-rays of long bones before the start of alendronate and approximately one year after its use. RESULTS: Eleven patients

  6. Treating Vomiting

    Science.gov (United States)

    ... hours. Your pediatrician usually won’t prescribe a drug to treat the vomiting, but some doctors will prescribe antinausea medications to children. If your child also has diarrhea, ask your pediatrician for instructions on giving liquids ...

  7. Treating Meningitis

    Science.gov (United States)

    ... David C. Spencer, MD Steven Karceski, MD Treating meningitis Steven Karceski, MD WHAT DID THE AUTHORS STUDY? ... study, “ Dexamethasone and long-term survival in bacterial meningitis, ” Dr. Fritz and his colleagues carefully evaluated 2 ...

  8. On breaks of the Indian monsoon

    Indian Academy of Sciences (India)

    Sulochana Gadgil; P V Joseph

    2003-12-01

    For over a century, the term break has been used for spells in which the rainfall over the Indian monsoon zone is interrupted. The phenomenon of `break monsoon' is of great interest because long intense breaks are often associated with poor monsoon seasons. Such breaks have distinct circulation characteristics (heat trough type circulation) and have a large impact on rainfed agriculture.Although interruption of the monsoon rainfall is considered to be the most important feature of the break monsoon, traditionally breaks have been identified on the basis of the surface pressure and wind patterns over the Indian region. We have defined breaks (and active spells) on the basis of rainfall over the monsoon zone. The rainfall criteria are chosen so as to ensure a large overlap with the traditional breaks documented by Ramamurthy (1969) and De et al (1998). We have identified these rainbreaks for 1901-89. We have also identified active spells on the basis of rainfall over the Indian monsoon zone. We have shown that the all-India summer monsoon rainfall is significantly negatively correlated with the number of rainbreak days (correlation coefficient −0.56) and significantly positively correlated with the number of active days (correlation coefficient 0.47).Thus the interannual variation of the all-India summer monsoon rainfall is shown to be related to the number of days of rainbreaks and active spells identified here. There have been several studies of breaks (and also active spells in several cases) identified on the basis of different criteria over regions differing in spatial scales (e.g., Webster et al 1998; Krishnan et al 2000; Goswami and Mohan 2000; and Annamalai and Slingo 2001). We find that there is considerable overlap between the rainbreaks we have identified and breaks based on the traditional definition. There is some overlap with the breaks identified by Krishnan et al (2000) but little overlap with breaks identified by Webster et al (1998). Further

  9. Social influences on morphine sensitization in adolescent females

    OpenAIRE

    2010-01-01

    We recently observed that social interactions influence morphine responsiveness in adolescent males. Given sex-related differences in both social interactions and responses to morphine, the present study examines social influences on morphine sensitization in adolescent female mice. Four experimental groups were examined: [1] morphine-treated mice (twice daily, 10–40 mg/kg, s.c.) housed physically and visually separated from saline-treated mice (‘morphine only’), [2] morphine-treated mice hou...

  10. Dynamical gauge symmetry breaking on the lattice

    Energy Technology Data Exchange (ETDEWEB)

    Farakos, K.; Koutsoumbas, G.; Zoupanos, G. (National Research Centre for the Physical Sciences Democritos, Athens (Greece))

    1990-10-11

    We study, using lattice techniques, the dynamical symmetry breaking of a three-dimensional theory that mimics the electroweak sector of the standard model. We show that in the strong coupling limit of a QCD-like theory the fermion condensates which are produced induce dynamical symmetry breaking of the sector corresponding to the electroweak gauge group. (orig.).

  11. Charge-symmetry-breaking nucleon form factors

    CERN Document Server

    Kubis, Bastian

    2009-01-01

    A quantitative understanding of charge-symmetry breaking is an increasingly important ingredient for the extraction of the nucleon's strange vector form factors. We review the theoretical understanding of the charge-symmetry-breaking form factors, both for single nucleons and for Helium-4.

  12. Prognostic factors of improvement in health-related quality of life in atomoxetine-treated children and adolescents with attention-deficit/hyperactivity disorder, based on a pooled analysis.

    Science.gov (United States)

    Montoya, Alonso; Quail, Deborah; Anand, Ernie; Cardo, Esther; Alda, José A; Escobar, Rodrigo

    2014-03-01

    The objective of this study is to identify prognostic factors of treatment response to atomoxetine in improvement of health-related quality of life (HR-QoL), measured by the Child Health and Illness Profile-Child Edition Parent Report Form (CHIP-CE PRF) Achievement and Risk Avoidance domains, in children and adolescents with attention-deficit/hyperactivity disorder (ADHD). Pooled data from 3 placebo-controlled trials and separate data from 3 open-label trials of atomoxetine in children and adolescents with ADHD were analyzed using logistic regression methods. Based on baseline impairment in the Achievement and/or Risk Avoidance domains (CHIP-CE PRF Risk Avoidance domains. Data of 190 and 183 subjects from the pooled sample, and 422 and 355 subjects from the open-label trials were included in the analysis of Achievement and Risk Avoidance domains. Baseline CHIP-CE subdomain scores proved to be the most robust prognostic factors for treatment outcome in both domains, based on data from the pooled sample of double-blind studies and from the individual open-label studies (odds ratios [OR] 0.74-1.56, p ADHD Rating Scale scores in the first 4-6 weeks) was another robust prognostic factor, based on data from the open-label studies (OR 2.99-6.19, p factors of atomoxetine treatment outcome in HR-QoL in children and adolescents with ADHD.

  13. Big break for charge symmetry

    CERN Document Server

    Miller, G A

    2003-01-01

    Two new experiments have detected charge-symmetry breaking, the mechanism responsible for protons and neutrons having different masses. Symmetry is a crucial concept in the theories that describe the subatomic world because it has an intimate connection with the laws of conservation. The theory of the strong interaction between quarks - quantum chromodynamics - is approximately invariant under what is called charge symmetry. In other words, if we swap an up quark for a down quark, then the strong interaction will look almost the same. This symmetry is related to the concept of sup i sospin sup , and is not the same as charge conjugation (in which a particle is replaced by its antiparticle). Charge symmetry is broken by the competition between two different effects. The first is the small difference in mass between up and down quarks, which is about 200 times less than the mass of the proton. The second is their different electric charges. The up quark has a charge of +2/3 in units of the proton charge, while ...

  14. Tricky Treats

    Centers for Disease Control (CDC) Podcasts

    2008-08-04

    The Eagle Books are a series of four books that are brought to life by wise animal characters - Mr. Eagle, Miss Rabbit, and Coyote - who engage Rain That Dances and his young friends in the joy of physical activity, eating healthy foods, and learning from their elders about health and diabetes prevention. Tricky Treats shows children the difference between healthy snacks and sweet treats.  Created: 8/4/2008 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP).   Date Released: 8/5/2008.

  15. Research progress on dam-break floods

    KAUST Repository

    Wu, Jiansong

    2011-08-01

    Because of the catastrophic effects downstream of dam-break failure, more and more researchers around the world have been working on the study of dam-break flows to accurately forecast the downstream inundation mapping. With the rapid development of computer hardware and computing techniques, numerical study on dam-break flows has been a popular research subject. In the paper, the numerical methodologies used to solve the governing partial differential equations of dam-break flows are classified and summarized, and their characteristics and applications are discussed respectively. Furthermore, the fully-developed mathematical models developed in recent decades are reviewed, and also introduced the authors\\' on-going work. Finally, some possible future developments on modeling the dam-break flows and some solutions are presented and discussed. © 2011 IEEE.

  16. Numerical study of airflow over breaking waves

    Science.gov (United States)

    Yang, Zixuan; Shen, Lian

    2016-11-01

    We present direct numerical simulation (DNS) results on airflow over breaking waves. Air and water are simulated as a coherent system. The initial condition for the simulation is a fully-developed turbulent airflow over strongly-forced steep waves. The airflow is driven by a shear stress at the top. The effects of the initial wave steepness and wave age are studied systematically. Because wave breaking is an unsteady process, we use ensemble averaging of a large number of runs to obtain turbulent statistics. Simulation results show that the airflow above does not see the wave trough during wave breaking. Vortex structures at different stages of wave breaking are analyzed based on a linear stochastic estimation method. It is found that the wave breaking alters the pattern of vortex structures.

  17. A laboratory study of breaking waves

    Directory of Open Access Journals (Sweden)

    Jaros³aw Têgowski

    2004-09-01

    Full Text Available This paper deals with some aspects of the wave-breaking phenomenon. The objectives were to study wave-breaking criteria, and the probability of whitecap coverage under fully controlled wave conditions. An additional task was to in vestigate the characteristic spectral features of the noise produced by breaking waves and the acoustic energy generated during wave breaking events. A controlled experiment was carried out in the Ocean Basin Laboratory at MARINTEK, Trondheim (Norway. Waves were generated by a computer-controlled multi-flap wave maker, which reproduced a realistic pattern of the sea surface for the prescribed spectra. Using wave staff recordings and photographic techniques, correlations between the breaking parameters and the radiated acoustic emissions were established.

  18. Adolescent loneliness.

    Science.gov (United States)

    Williams, E G

    1983-01-01

    The purpose of this study was to investigate the phenomenon of loneliness in delinquent adolescents with regard to types of delinquency offenses committed, demographic characteristics, and personality characteristics in the areas of interpersonal needs for inclusion, control, and affection. The types of delinquency offenses were categorized as burglary, runaway, drugs, assault, and incorrigible. The demographic variables examined were age, sex, race, family rank or birth order, family structure in terms of parental presence, family income level, religion, and geographic locale. A sample of 98 adolescents was obtained from juvenile detention facilities in three metropolitan areas in the United States. Subjects ranged in age from 12 to 18. Subjects were asked to complete the Loneliness Questionnaire as a self-reported measure of loneliness. Subjects also provided information about themselves relative to demographic characteristics and completed the FIRO-B Questionnaire, which measured interpersonal needs for inclusion, control, and affection. The results revealed no significant differences with regard to any of the demographic variables when the effect of each was considered alone. However, there was a significant effect on loneliness by income when considered jointly with other demographic variables. Adolescents from the middle income group expressed more loneliness than those from the upper and lower income groups. No significant differences were observed with regard to personality characteristics related to interpersonal needs for inclusion and affection, but delinquent adolescents with medium to high needs for control indicated significantly more feelings of loneliness than delinquent adolescents with low needs for control.

  19. Breaking soliton equations and negative-order breaking soliton equations of typical and higher orders

    Indian Academy of Sciences (India)

    ABDUL-MAJID WAZWAZ

    2016-11-01

    We develop breaking soliton equations and negative-order breaking soliton equations of typical and higher orders. The recursion operator of the KdV equation is used to derive these models.We establish the distinctdispersion relation for each equation. We use the simplified Hirota’s method to obtain multiple soliton solutions for each developed breaking soliton equation. We also develop generalized dispersion relations for the typical breaking soliton equations and the generalized negative-order breaking soliton equations. The results provide useful information on the dynamics of the relevant nonlinear negative-order equations.

  20. Interventions for treating obesity in children

    NARCIS (Netherlands)

    Oude Luttikhuis, Hiltje; Baur, Louise; Jansen, Hanneke; Shrewsbury, Vanessa A.; O'Malley, Claire; Stolk, Ronald P.; Summerbell, Carolyn D.

    2009-01-01

    Background Child and adolescent obesity is increasingly prevalent, and can be associated with significant short- and long-term health consequences. Objectives To assess the efficacy of lifestyle, drug and surgical interventions for treating obesity in childhood. Search strategy We searched CENTRAL o

  1. Science Illiteracy: Breaking the Cycle

    Science.gov (United States)

    Lebofsky, L. A.; Lebofsky, N. R.

    2003-12-01

    At the University of Arizona, as at many state universities and colleges, the introductory science classes for non-science majors may be the only science classes that future K--8 teachers will take. The design of the UA's General Education program requires all future non-science certified teachers to take the General Education science classes. These classes are therefore an ideal venue for the training of the state's future teachers. Many students, often including future teachers, are ill-prepared for college, i.e., they lack basic science content knowledge, basic mathematics skills, and reading and writing skills. They also lack basic critical thinking skills and study skills. It is within this context that our future teachers are trained. How do we break the cycle of science illiteracy? There is no simple solution, and certainly not a one-size-fits-all panacea that complements every professor's style of instruction. However, there are several programs at the University of Arizona, and also principles that I apply in my own classes, that may be adaptable in other classrooms. Assessment of K--12 students' learning supports the use of inquiry-based science instruction. This approach can be incorporated in college classes. Modeling proven and productive teaching methods for the future teachers provides far more than ``just the facts,'' and all students gain from the inquiry approach. Providing authentic research opportunities employs an inquiry-based approach. Reading (outside the textbook) and writing provide feedback to students with poor writing and critical thinking skills. Using peer tutors and an instant messaging hot line gives experience to the tutors and offers "comfortable" assistance to students.

  2. Morning and evening behavior in children and adolescents treated with atomoxetine once daily for Attention-Deficit/Hyperactivity Disorder (ADHD: Findings from two 24-week, open-label studies

    Directory of Open Access Journals (Sweden)

    Schacht Alexander

    2009-02-01

    Full Text Available Abstract Background The impact of once daily atomoxetine treatment on symptoms in children and adolescents with ADHD may vary over the day. In order to capture such variations, two studies were undertaken in children and adolescents with ADHD using two instruments that capture morning and evening behavior and ADHD-related difficulties over the day. This secondary measure analysis builds on two primary analyses that were conducted separately for children and adolescents and also published separately. Methods In two open-label studies, ADHD patients aged 6–17 years (n = 421, received atomoxetine in the morning (target-dose 0.5–1.2 mg/kg/day for up to 24 weeks. Morning and evening behavior was assessed using the investigator-rated Weekly Rating of Evening and Morning Behavior (WREMB-R scale. ADHD-related difficulties at various times of the day (morning, during school, during homework, evening were assessed using the Global Impression of Perceived Difficulties (GIPD scale, rated by patients, parents and physicians. Data from both studies were combined for this secondary measure analysis. Results Both WREMB-R subscores decreased significantly over time, the evening subscore from 13.7 (95% CI 13.2;14.2 at baseline to 8.0 (7.4;8.5 at week 2, the morning subscore from 4.3 (4.0;4.5 to 2.4 (2.2;2.6. Scores then remained stable until week 24. All GIPD items improved correspondingly. At all times of the day, patients rated ADHD-related difficulties as less severe than parents and physicians. Conclusion These findings from two open-label studies suggest that morning and evening behavior and ADHD-related difficulties in the mornings and evenings improve over time with once daily atomoxetine treatment.

  3. Particle production from symmetry breaking after inflation

    CERN Document Server

    García-Bellido, J; Garcia-Bellido, Juan; Morales, Ester Ruiz

    2002-01-01

    Recent studies suggest that the process of symmetry breaking after inflation typically occurs very fast, within a single oscillation of the symmetry-breaking field, due to the spinodal growth of its long-wave modes, otherwise known as `tachyonic preheating'. In this letter we show how this sudden transition from the false to the true vacuum can induce a significant production of particles, bosons and fermions, coupled to the symmetry-breaking field. We find that this new mechanism of particle production in the early Universe may have interesting consequences for the origin of dark matter and the generation of the observed baryon asymmetry through leptogenesis.

  4. Interpersonal Theory and Music Techniques: A Case Study for a Family With a Depressed Adolescent

    Science.gov (United States)

    Hendricks, C. Bret; Bradley, Loretta J.

    2005-01-01

    Interpersonal psychotherapy (IPT-A) is a brief, time-limited therapy developed for use with adolescents diagnosed with major depression. IPT-A has been shown to be effective with adolescents in family counseling milieus. Music therapy techniques also have been successfully used to treat adolescent depression. This article provides mental health…

  5. Treatment of 56 Cases of Women with Post-adolescent Acne by Auricular Point Sticking Method

    Institute of Scientific and Technical Information of China (English)

    DING Min; JIANG Ya-qiu; CUI Xue-jun

    2008-01-01

    @@ Acne is a common disorder in adolescence. However, more and more patients are over 25 years old. This type of acne is recurrent, so it is called post-adolescence acne. The author treated 56 cases of women with post-adolescence acne by auricular point sticking method, and obtained excellent results. It is reported as follows.

  6. Unconventional supersymmetry and its breaking

    Energy Technology Data Exchange (ETDEWEB)

    Alvarez, Pedro D., E-mail: alvarez@physics.ox.ac.uk [Centro de Estudios Científicos (CECS), Av. Arturo Prat 514, Valdivia (Chile); Universidad Andrés Bello, Av. República 440, Santiago (Chile); Rudolf Peierls Centre for Theoretical Physics, University of Oxford, Oxford (United Kingdom); Pais, Pablo, E-mail: pais@cecs.cl [Centro de Estudios Científicos (CECS), Av. Arturo Prat 514, Valdivia (Chile); Universidad Andrés Bello, Av. República 440, Santiago (Chile); Zanelli, Jorge, E-mail: z@cecs.cl [Centro de Estudios Científicos (CECS), Av. Arturo Prat 514, Valdivia (Chile); Universidad Andrés Bello, Av. República 440, Santiago (Chile)

    2014-07-30

    We present a gauge theory for a superalgebra that includes an internal gauge (G) and local Lorentz (so(1,D−1)) algebras. These two symmetries are connected by fermionic supercharges. The field content of the system includes a (non-)abelian gauge potential A, a spin-1/2 Dirac spinor ψ, the Lorentz connection ω{sup ab}, and the vielbein e{sub μ}{sup a}. The connection one-form A is in the adjoint representation of G, while ψ is in the fundamental. In contrast to standard supersymmetry and supergravity, the metric is not a fundamental field and is in the center of the superalgebra: it is not only invariant under the internal gauge group, G, and under Lorentz transformations, SO(1,D−1), but is also invariant under supersymmetry. The distinctive features of this theory that mark the difference with standard supersymmetries are: i) the number of fermionic and bosonic states is not necessarily the same; ii) there are no superpartners with equal mass; iii) although this supersymmetry originates in a local gauge theory and gravity is included, there is no gravitino; iv) fermions acquire mass from their coupling to the background or from higher order self-couplings, while bosons remain massless. In odd dimensions, the Chern–Simons (CS) form provides an action that is (quasi-)invariant under the entire superalgebra. In even dimensions, the Yang–Mills (YM) form is the only natural option and the symmetry breaks down to G⊗SO(1,D−1). In four dimensions, the construction follows the Townsend–Mac Dowell–Mansouri approach, starting with an osp(4|2)∼usp(2,2|1) connection. Due to the absence of osp(4|2)-invariant traces in four dimensions, the resulting Lagrangian is only invariant under u(1)⊕so(3,1), which includes a Nambu–Jona-Lasinio (NJL) term. In this case, the Lagrangian depends on a single dimensionful parameter that fixes Newton's constant, the cosmological constant and the NJL coupling.

  7. Adolescent growth and development.

    Science.gov (United States)

    Chulani, Veenod L; Gordon, Lonna P

    2014-09-01

    Adolescence is a developmental stage defined by physical and psychosocial maturation. This article reviews normal pubertal development and the evaluation and management of adolescents with suspected pubertal abnormalities and provides an overview of adolescent psychosocial development.

  8. Adolescent homosexuality.

    Science.gov (United States)

    Stronski Huwiler, S M; Remafedi, G

    1998-01-01

    Homosexuality has existed in all civilizations, but societal disapproval and cultural taboos have negatively influenced its recognition. A significant percentage of youths identify themselves as homosexual, and even more experience sex with the same sex or are confused about sexual feelings. A unifying etiological theory attributes the expression of sexual orientation to genes that shape the central nervous system's development, organization, and structure via prenatal sex steroids. Environmental factors may influence the expression of genetic potential. Several models of psychosocial development describe initial stages of awareness and confusion about same-sex attractions, followed by acknowledgement of homosexuality, disclosure to others, and eventual integration of sexual identity into a comprehensive sense of self. Stressors related to isolation, stigma, and violence may predispose homosexual adolescents to impaired social, emotional, and physical health, resulting in depression and suicide, school problems, substance abuse, running away eating disorders, risky sexual behavior, and illegal conduct. As with all adolescents, the overall goals in the care of homosexual youth are to promote normal adolescent development, social and emotional well-being, and physical health. A comprehensive, multidisciplinary approach is required to address medical, mental health, and psychosocial issues within the context of the adolescents' community and culture.

  9. Symmetry Breaking for Answer Set Programming

    CERN Document Server

    Drescher, Christian

    2010-01-01

    In the context of answer set programming, this work investigates symmetry detection and symmetry breaking to eliminate symmetric parts of the search space and, thereby, simplify the solution process. We contribute a reduction of symmetry detection to a graph automorphism problem which allows to extract symmetries of a logic program from the symmetries of the constructed coloured graph. We also propose an encoding of symmetry-breaking constraints in terms of permutation cycles and use only generators in this process which implicitly represent symmetries and always with exponential compression. These ideas are formulated as preprocessing and implemented in a completely automated flow that first detects symmetries from a given answer set program, adds symmetry-breaking constraints, and can be applied to any existing answer set solver. We demonstrate computational impact on benchmarks versus direct application of the solver. Furthermore, we explore symmetry breaking for answer set programming in two domains: firs...

  10. Water Breaking: Understand This Sign of Labor

    Science.gov (United States)

    Healthy Lifestyle Labor and delivery, postpartum care Water breaking worries? Prepare yourself for childbirth by getting the facts about this important sign of labor. By Mayo Clinic Staff If you're ...

  11. Psychiatric Comorbidities among Female Adolescents with Anorexia Nervosa

    Science.gov (United States)

    Salbach-Andrae, Harriet; Lenz, Klaus; Simmendinger, Nicole; Klinkowski, Nora; Lehmkuhl, Ulrike; Pfeiffer, Ernst

    2008-01-01

    This study investigated current comorbid Axis I diagnoses associated with Anorexia Nervosa (AN) in adolescents. The sample included 101 female adolescents treated at a psychiatric unit for primary DSM-IV diagnoses of AN. 73.3% of the AN patients were diagnosed as having a current comorbidity of at least one comorbid Axis I diagnosis, with no…

  12. Breaking antidunes: Cyclic behavior due to hysteresis

    DEFF Research Database (Denmark)

    Deigaard, Rolf

    2006-01-01

    The cyclic behavior of breaking antidunes (growth, breaking of surface wave, obliteration) is investigated by use of a numerical model. The model includes the transition between supercritical and transcritical flow. As the antidune grows the flow becomes transcritical and a hydraulic jump is form...... upstream of the antidune crest. The relation between growth of the antidune and supercritical flow and between decay and transcritical flow is shown, and the significance of hysteresis in the flow conditions is investigated....

  13. Symmetry Breaking and Second Order Phase Transitions

    Institute of Scientific and Technical Information of China (English)

    ZhangFengshou; R.M.Lynden-Bell

    2003-01-01

    In an earlier paper we showed that symmetry breaking could be induced in the triiodide ion by varying the solvent. Experiments and simulations suggest that protic solvents which can form hydrogen bonds with a negative ion cause symmetry breaking of the ion, so that the charge becomes concentrated at one end of the ion and the corresponding bond elongates. We suggested that one could draw an analogy between the mean field Ising model with free energy,

  14. Dynamical supersymmetry breaking and unification of couplings

    CERN Document Server

    Dubovsky, S L; Troitsky, S V

    1997-01-01

    We consider the possibility of unification of the Supersymmetric Standard Model gauge groups with those of the dynamical supersymmetry breaking (DSB) sector in theories with gauge mediated supersymmetry breaking. We find constraints on the DSB gauge group beta function that come from unification of the gauge coupling constants of the two sectors. These constraints are satisfied by a fairly wide class of models. We discuss possible unification scenarios in the context of a simple model.

  15. Dormancy Breaking in Ormosia arborea Seeds

    OpenAIRE

    Edilma Pereira Gonçalves; Franklim Sales de Jesus Soares; Sérgio dos Santos Silva; Débora de Souza Tavares; Jeandson Silva Viana; Brenda Colleen Clifton Cardoso

    2011-01-01

    Ormosia arborea is a tree species planted in urban areas and used to restore degraded areas. Its seeds are dormant and propagation is difficult. This study compares different dormancy breaking methods and physiological seed quality and seedling production. The seeds were germinated in sand in the laboratory of the Universidade Estadual de Santa Cruz, Ilhéus, Bahia, Brazil. The following dormancy breaking treatments were applied: control (intact seeds), 100°C water immersion; boiling water imm...

  16. Is soft breaking of BRST symmetry consistent?

    CERN Document Server

    Lavrov, Peter; Reshetnyak, Alexander

    2011-01-01

    A definition of soft breaking of BRST symmetry in the field-antifield formalism is proposed, valid for general gauge theories and arbitrary gauge fixing. The Ward identities for the generating functionals of Green's functions are derived, and their gauge dependence is investigated. We present a generalization of the Gribov-Zwanziger action to a one-parameter linear gauge. It is argued that gauge theories with a soft breaking of BRST symmetry are inconsistent.

  17. String breaking in two-dimensional QCD

    CERN Document Server

    Hornbostel, K J

    1999-01-01

    I present results of a numerical calculation of the effects of light quark-antiquark pairs on the linear heavy-quark potential in light-cone quantized two-dimensional QCD. I extract the potential from the Q-Qbar component of the ground-state wavefunction, and observe string breaking at the heavy-light meson pair threshold. I briefly comment on the states responsible for the breaking.

  18. Phil Anderson and Gauge Symmetry Breaking

    Science.gov (United States)

    Witten, Edward

    In this article, I describe the celebrated paper that Phil Anderson wrote in 1962 with early contributions to the idea of gauge symmetry breaking in particle physics. To set the stage, I describe the work of Julian Schwinger to which Anderson was responding, and also some of Anderson's own work on superconductivity that provided part of the context. After describing Anderson's work I describe the later work of others, leading to the modern understanding of gauge symmetry breaking in weak interactions...

  19. Kinematic criterion for breaking of shoaling waves

    Science.gov (United States)

    Liberzon, Dan; Itay, Uri

    2016-11-01

    Validity of a kinematic criterion for breaking of shoaling waves was examined experimentally. Results obtained by simultaneous measurements of water surface velocity by PTV and of the propagation velocity of a steep crest up to the point of breaking inception during shoaling will be reported. The experiments performed in a large wave tank examining breaking behavior of gentle spillers during shoaling on three different slopes suggest a validity of the recently proposed kinematic criterion. The breaking inception was found to occur when the horizontal velocity of the water surface on the steep (local steepness of 0.41-0.6) crest reaches a threshold value of 0.85-0.95 of that of the crest propagation. The exact moment and position of breaking inception detected using a Phase Time Method (PTM), characterizing a unique shape of the local frequency fluctuations at the inception. Future implementation of the PTM method for detection of breaking events in irregular wave fields will be discussed. Supported by German-Israeli Foundation for Scientific Research and Development (GIF) Grant #2019392.

  20. Warp Breaks Detection in Jacquard Weaving Using MEMS: Effect of Weave on Break Signals

    Directory of Open Access Journals (Sweden)

    Jin H Lee, Ph.D.

    2008-03-01

    Full Text Available This paper reports a study to detect warp breaks in terms of weave structure using MEMS accelerometer based detection system. The system is briefly described. The output signals of MEMS sensors, which were mounted on harness cords of a Jacquard machine, at the moment of warp yarn break and after the break for a broad range of basic weaves were acquired during weaving. The weaves investigated are commonly used in Jacquard weaving to form patterns. The strength of the MEMS output acceleration signals was analyzed in time domain. The results show that the system is capable of detecting warp yarn breaks for the broad range of weaves studied.

  1. Family dysfunction in adolescents with suicidal behavior and in adolescents with conduct disorders

    Directory of Open Access Journals (Sweden)

    Ivanović-Kovačević Svetlana

    2005-01-01

    Full Text Available Introduction. The period of life known as adolescence generally refers to transition from childhood to adulthood. Adolescents' progress toward autonomy involves remaining connected with, as well as separated from parents. Young people and their parents usually have mixed feelings about adolescent autonomy and attachment. An estimated 50% of children born in the 80s have spent part of their developmental years in single-parent households. Divorce is almost always a stressful event in children's lives. Youthful suicide rate has increased dramatically and is the third leading cause of death among 15-19 year olds. Conduct disorder is one of the most frequently diagnosed conditions in adolescents. Suicidal adolescents and adolescents with conduct disorder are much more likely than their peers to have grown up in disrupted, disorganized homes with lack of attachment between parents and their children. Material and methods This prospective study was carried out during 2002, 2003, and 2004. The research included 60 adolescents treated at the Center for Child and Adolescent Psychiatry in Novi Sad, 30 with diagnosed conduct disorder and 30 with suicidal behavior. Results Along with other kinds of distress, suicidal adolescents have experienced an escalation of family problems a few months prior to attempted suicide. Discussion Divorce and life in single-parent households is almost always a stressful period in children's lives. Conduct disorder and suicidal behavior represent a desperate cry for help. Conclusion Most adolescents in both groups live in single-parent house­holds. These young people have frequently passed into adolescence with little reason to feel that they could rely on their parents for support, or on their home as a place of sanctuary. .

  2. Jet simulations and gamma-ray burst afterglow jet breaks

    NARCIS (Netherlands)

    van Eerten, H. J.; Meliani, Z.; Wijers, R.A.M.J.; Keppens, R.

    2010-01-01

    The conventional derivation of the gamma-ray burst afterglow jet break time uses only the blast wave fluid Lorentz factor and therefore leads to an achromatic break. We show that in general gamma-ray burst afterglow jet breaks are chromatic across the self-absorption break. Depending on circumstance

  3. Jet simulations and gamma-ray burst afterglow jet breaks

    NARCIS (Netherlands)

    van Eerten, H. J.; Meliani, Z.; Wijers, Ramj; Keppens, R.

    2011-01-01

    The conventional derivation of the gamma-ray burst afterglow jet break time uses only the blast wave fluid Lorentz factor and therefore leads to an achromatic break. We show that in general gamma-ray burst afterglow jet breaks are chromatic across the self-absorption break. Depending on circumstance

  4. Jet simulations and gamma-ray burst afterglow jet breaks

    NARCIS (Netherlands)

    van Eerten, H.J.; Meliani, Z.; Wijers, R.A.M.J.; Keppens, R.

    2012-01-01

    The conventional derivation of the gamma-ray burst afterglow jet break time uses only the blast wave fluid Lorentz factor and therefore leads to an achromatic break. We show that in general gamma-ray burst afterglow jet breaks are chromatic across the self-absorption break. Depending on circumstance

  5. 雌激素联合二甲双胍治疗青春期多囊卵巢综合症效果分析%Effect of metformin combined estrogen in treating adolescent polycystic ovary syndrome

    Institute of Scientific and Technical Information of China (English)

    张雪花; 徐金贵; 陈双忠

    2015-01-01

    目的:研究雌激素联合二甲双胍治疗青春期多囊卵巢综合症的临床效果。方法:选取2010年3月至2014年5月共120例于我院就诊的青春期多囊卵巢综合征患者,将其半随机分为研究组和对照组,其中研究组患者采用雌激素联合二甲双胍治疗,对照组患者采用雌激素补充治疗。对比两组患者空腹胰岛素变化、空腹血糖、血浆性激素变化情况。结果:两组患者 FIN、FBS 在治疗3个月后均有明显改善,且研究组改善明显,具有统计学差异(P <0.05);两组患者血浆性激素 T、LH、FSH、LH/FSH 在治疗3个月后均有下降,且研究组下降明显,具有统计学差异(P <0.05)。结论:雌激素联合二甲双胍治疗青春期多囊卵巢综合征可有效降低雄激素水平,改善患者胰岛素抵抗、卵巢功能、临床症状,效果满意。%Objectives:To study the effect of metformin combined estrogen in the treatment of adolescent polycystic ovary syndrome.Methods:120 adolescent polycystic ovary syndrome patients between March 2011 and May 2014 selected and half -randomly divided into study group and control group.The patients in study group re-ceived estrogen combined with metformin,while patients in control group employed estrogen only.The fasting insu-lin changes,fasting glucose and plasma sex hormone of the two groups were compared.Results:Both groups of pa-tients had improved FIN,FBS after three months,and the research group improved more obviously,with statistically significant difference (P <0.05).Both groups of patients had decreased plasma sex hormone T,LH,FSH,LH/FSH after three months,and the research group decreased more obviously,with statistically difference (P <0.05). Conclusion:In the treatment of adolescent polycystic ovary syndrome,estrogen combined with metformin can effec-tively reduce androgen levels,improve the patients’insulin resistance,ovarian function and clinical symptoms

  6. Integrating translational neuroscience to improve drug abuse treatment for adolescents.

    Science.gov (United States)

    Boyce, Cheryl Anne; Lynne-Landsman, Sarah D

    2013-06-01

    Adolescence is an exciting and challenging period of maturation, rapid brain development, and developmental changes in neurobiological, neurocognitive, and neurobehavioral processes. Although behavioral therapies available for adolescent substance abuse have increased, effectiveness research in this area lags considerably behind that of clinical research on treatment for drug-abusing adults. Behavioral treatment approaches show significant promise for treating drug-abusing adolescents, but many have not incorporated innovations in neuroscience on brain development, cognitive processes, and neuroimaging. Linking developmental neuroscience with behavioral treatments can create novel drug abuse interventions and increase the effectiveness of existing interventions for substance-abusing adolescents. Contemporary research on brain development, cognition, and neuroscience is ripe for translation to inform developmentally sensitive drug abuse treatments for adolescents. Neuroscientists and interventionists are challenged to build mutual collaborations for integration of neuroscience and drug abuse treatment for adolescents.

  7. Break-glass handling exceptional situations in access control

    CERN Document Server

    Petritsch, Helmut

    2014-01-01

    Helmut Petritsch describes the first holistic approach to Break-Glass which covers the whole life-cycle: from access control modeling (pre-access), to logging the security-relevant system state during Break-Glass accesses (at-access), and the automated analysis of Break-Glass accesses (post-access). Break-Glass allows users to override security restrictions in exceptional situations. While several Break-Glass models specific to given access control models have already been discussed in research (e.g., extending RBAC with Break-Glass), the author introduces a generic Break-Glass model. The pres

  8. Report of Break Out Group 1

    DEFF Research Database (Denmark)

    Alward, Randy; Carley, Kathleen M.; Madsen, Fredrik Huitfeldt

    2006-01-01

    To help understand a network and its ability to continue operating when under attack, the break out group discussed issues that need to be considered when presenting network vulnerability information to an analyst, manager or commander in effective support of that person's "observe, orient, decide......, action" (OODA) loop. The break out group discussed vulnerability presentation needs common across various application domains, particularly in support of network discovery and network analysis tasks in those domains. Finally, the break out group wished to determine whether there is a means...... of characterizing a vulnerability. This would take into account the potential for the vulnerability to be exploited as well as the potential impact on the operations supported by the network, and on the network structure itself, of a successful exploit of that vulnerability....

  9. Workshop on electroweak symmetry breaking: proceedings

    Energy Technology Data Exchange (ETDEWEB)

    Hinchliffe, I. (ed.)

    1984-10-01

    A theoretical workshop on electroweak symmetry breaking at the Superconducting Supercollider was held at Lawrence Berkeley Laboratory, June 4-22, 1984. The purpose of the workshop was to focus theoretical attention on the ways in which experimentation at the SSC could reveal manifestations of the phenomenon responsible for electroweak symmetry breaking. This issue represents, at present, the most compelling scientific argument for the need to explore the energy region to be made accessible by the SSC, and a major aim of the workshop was to involve a broad cross section of particle theorists in the ongoing process of sharpening the requirements for both accelerator and detector design that will ensure detection and identification of meaningful signals, whatever form the electroweak symmetry breaking phenomenon should actually take. Separate entries were prepared for the data base for the papers presented.

  10. Isospin Breaking Effects on the Lattice

    CERN Document Server

    Tantalo, Nazario

    2013-01-01

    Isospin symmetry is not exact and the corrections to the isosymmetric limit are, in general, at the percent level. For gold plated quantities, such as pseudoscalar meson masses or the kaon leptonic and semileptonic decay rates, these effects are of the same order of magnitude of the errors quoted in nowadays lattice calculations and cannot be neglected any longer. In this talk I discuss the methods that have been developed in the last few years to calculate isospin breaking corrections by starting from first principles lattice simulations. In particular, I discuss how to perform a combined QCD+QED lattice simulation and a renormalization prescription to be used in order to separate QCD from QED isospin breaking effects. A brief review of recent lattice results of isospin breaking effects on the hadron spectrum is also included.

  11. Large eddy simulation of breaking waves

    DEFF Research Database (Denmark)

    Christensen, Erik Damgaard; Deigaard, Rolf

    2001-01-01

    is described by large eddy simulation where the larger turbulent features are simulated by solving the flow equations, and the small scale turbulence that is not resolved by the flow model is represented by a sub-grid model. A simple Smagorinsky sub-grid model has been used for the present simulations......A numerical model is used to simulate wave breaking, the large scale water motions and turbulence induced by the breaking process. The model consists of a free surface model using the surface markers method combined with a three-dimensional model that solves the flow equations. The turbulence....... The incoming waves are specified by a flux boundary condition. The waves are approaching in the shore-normal direction and are breaking on a plane, constant slope beach. The first few wave periods are simulated by a two-dimensional model in the vertical plane normal to the beach line. The model describes...

  12. Gauge mediated supersymmetry breaking and neutrino anomalies

    CERN Document Server

    Joshipura, A S; Joshipura, Anjan S.; Vempati, Sudhir K.

    1999-01-01

    Supersymmetric standard model with softly broken lepton symmetry provides a suitable framework to accommodate the solar and atmospheric neutrino anomalies. This model contains a natural explanation for large mixing and hierarchal masses without fine tuning of the parameters. Neutrino spectrum is particularly constrained in the minimal messenger model (MMM) of gauge mediated SUSY breaking, since all SUSY breaking effects are controlled in MMM by a single parameter. We study the structure of neutrino masses and mixing both in MMM and in simple extensions of it in the context of solar and atmospheric neutrino anomalies.

  13. Breaking the cycle of family violence

    OpenAIRE

    Heikkinen, Eeva

    2009-01-01

    ABSTRACT Heikkinen Eeva. Breaking the cycle of family violence. Järvenpää, Autumn 2009, 51 pages, 2 appendices. Diaconia University of Applied Sciences, Diak South, Järvenpää. Degree Programme in Social Services. The research was done in a shelter for battered family members, a place where families can go, when they are unable to stay at home because of violence. The aim of the research was to find out the role of the shelter in breaking the cycle of family violence and to ...

  14. Dynamical Symmetry Breaking in Warped Compactifications

    CERN Document Server

    Rius, N

    2001-01-01

    We study dynamical electroweak symmetry breaking in the Randall-Sundrum scenario. We show that one extra dimension is enough to give the correct pattern of electroweak symmetry breaking in a simple model with gauge bosons and the right-handed top quark in the bulk. The top quark mass is also in agreement with experiment. Furthermore, we propose an extended scenario with all Standard Model gauge bosons and fermions propagating in the bulk, which naturally accommodates the fermion mass hierarchies. No new fields or interactions beyond the observed in the Standard Model are required.

  15. Factorization breaking in diffractive dijet photoproduction

    Energy Technology Data Exchange (ETDEWEB)

    Klasen, M. [Hamburg Univ. (Germany). 2. Inst. fuer Theoretische Physik]|[Centre National de la Recherche Scientifique, 38 - Grenoble (France). Univ. Joseph Fourier, Lab. de Physique Subatomique et de Cosmologie; Kramer, G. [Hamburg Univ. (Germany). 2. Inst. fuer Theoretische Physik

    2004-08-01

    We have calculated the diffractive dijet cross section in low-Q{sup 2} ep scattering in the HERA regime. The results of the calculation in LO and NLO are compared to recent experimental data of the H1 collaboration. We find that in LO the calculated cross sections are in reasonable agreement with the experimental results. In NLO, however, some of the cross sections disagree, showing that factorization breaking occurs in that order. By suppressing the resolved contribution by a factor of approximately three, good agreement with all the data is found. The size of the factorization breaking effects in diffractive dijet photoproduction agrees well with absorptive model predictions. (orig.)

  16. Factorization breaking in diffractive dijet photoproduction

    Energy Technology Data Exchange (ETDEWEB)

    Klasen, M. [Universite Joseph Fourier, CNRS-IN2P3, Laboratoire de Physique Subatomique et de Cosmologie, Grenoble (France); Universitaet Hamburg, II. Institut fuer Theoretische Physik, Hamburg (Germany); Kramer, G. [Universitaet Hamburg, II. Institut fuer Theoretische Physik, Hamburg (Germany)

    2004-12-01

    We have calculated the diffractive dijet cross section in low-Q{sup 2} ep scattering in the HERA regime. The results of the calculation in LO and NLO are compared to recent experimental data of the H1 Collaboration. We find that in LO the calculated cross sections are in reasonable agreement with the experimental results. In NLO, however, some of the cross sections disagree, showing that factorization breaking occurs in that order. By suppressing the resolved contribution by a factor of approximately three, good agreement with all the data is found. The size of the factorization breaking effects in diffractive dijet photoproduction agrees well with absorptive model predictions. (orig.)

  17. Effective dissipation: breaking time-reversal symmetry

    CERN Document Server

    Brown, Aidan I

    2016-01-01

    At molecular scales, fluctuations play a significant role and prevent biomolecular processes from always proceeding in a preferred direction, raising the question of how limited amounts of free energy can be dissipated to obtain directed progress. We examine the system and process characteristics that efficiently break time-reversal symmetry at fixed energy loss; in particular for a simple model of a molecular machine, an intermediate energy barrier produces unusually high asymmetry for a given dissipation. Such insight into symmetry-breaking factors that produce particularly high time asymmetry suggests generalizations to a broader class of systems.

  18. Mediation of supersymmetry breaking in extra dimensions

    CERN Document Server

    Scrucca, C A

    2004-01-01

    I review the mechanisms of supersymmetry breaking mediation that occur in sequestered models, where the visible and the hidden sectors are separated by an extra dimension and communicate only via gravitational interactions. By locality, soft breaking terms are forbidden at the classical level and reliably computable within an effective field theory approach at the quantum level. I present a self-contained discussion of these radiative gravitational effects and the resulting pattern of soft masses, and give an overview of realistic model building based on this set-up. I consider both flat and warped extra dimensions, as well as the possibility that there be localized kinetic terms for the gravitational fields.

  19. What records have we been breaking

    Science.gov (United States)

    Bartholow, J.M.; Milhous, R.

    2002-01-01

    a??Today was another record-breaking day,a?? the evening radio or television declares. High temperatures, low temperatures, floods, drought a?? take your choice. But how can we put these pronouncements in perspective? What do they really mean? We present two types of information in this article: 1) an analysis of daily air temperature and precipitation for Fort Collins and 2) an analysis of annual precipitation for Fort Collins. Each analysis provides a different meaning to the statement about a record-breaking day or year.

  20. Detecting Structural Breaks using Hidden Markov Models

    DEFF Research Database (Denmark)

    Ntantamis, Christos

    Testing for structural breaks and identifying their location is essential for econometric modeling. In this paper, a Hidden Markov Model (HMM) approach is used in order to perform these tasks. Breaks are defined as the data points where the underlying Markov Chain switches from one state to another....... The estimation of the HMM is conducted using a variant of the Iterative Conditional Expectation-Generalized Mixture (ICE-GEMI) algorithm proposed by Delignon et al. (1997), that permits analysis of the conditional distributions of economic data and allows for different functional forms across regimes...

  1. La poetica degli spazi di Breaking Bad

    Directory of Open Access Journals (Sweden)

    Sara Martin

    2015-12-01

    Full Text Available Breaking Bad (2008-2013 produced, thanks to the creativity of Vince Gilligan and his writing room, some of the most emblematic characters in the history of contemporary television. Also, the writers of Breaking Bad were able to devise places and spaces that play important symbolic functions: spaces of mediation, spaces of transit, sacred spaces. This article investigates the meanings and characteristics of some of these settings: the swimming pool, the White family home, the meth lab. The analysis considers also the relation between characters and spaces, paying particular attention to the places inhabited by the main character, Walter White.

  2. Numerical Study on Breaking Criteria for Solitary Waves

    Institute of Scientific and Technical Information of China (English)

    Chung-ren CHOU; Ruey-syan SHIH; John Z. YIM

    2003-01-01

    Studies of the breaking criteria for solitary waves on a slope are presented in this paper. The boundary element method is used to model the processes of shoaling and breaking of solitary waves on various slopes. Empirical formulae that can be used to characterize the breaking of solitary waves are presented. These include the breaking index, the wave height, the water depth, and the maximum particle velocity at the point of breaking. Comparisons with the results of other researches are given.

  3. Influence of night-breaks on flowering and phytohormones content in Hyoscyamus niger L.

    Directory of Open Access Journals (Sweden)

    Jan Kopcewicz

    2014-02-01

    Full Text Available Night-breaks caused both stimulated shoot growth and caused formation of flowers as well as a general increase in the content of phytohormones in leaves of the long-day plant Hyoscyamus niger L. At the time of flower formation in night-break treated plants, new gibberellin-like substances also appear. The results show that night-breaks cause similar changes in the phytohormones content as a long inductive photoperiod. It may be assumed that independently of the way of induction, the generative differentiation of long-day plants is always accompanied by a general increase in the amount of endogenous hormones and the appearance of new gibberellins. These results suggest the possibility of a morphogenetic role of hormones, especially gibberellins, in the phenomena of flower formation and differentiation.

  4. Path-breaking books in regional science

    NARCIS (Netherlands)

    Waldorf, BS

    2004-01-01

    This article presents a collection of regional science books that long-standing members of the Regional Science Association International (RSAI) identified as path-breaking books. The most frequently nominated books include the "classics" by Isard, the seminal books in urban economics by Alonso, Mut

  5. Variations on supersymmetry breaking and neutrino spectra

    Energy Technology Data Exchange (ETDEWEB)

    Borzumati, F.; Hamaguchi, K.; Nomura, Y.; Yanagida, T.

    2000-12-11

    The problem of generating light neutrinos within supersymmetric models is discussed. It is shown that the hierarchy of scales induced by supersymmetry breaking can give rise to suppression factors of the correct order of magnitude to produce experimentally allowed neutrino spectra.

  6. Geometrical hierarchy and spontaneous symmetry breaking

    Energy Technology Data Exchange (ETDEWEB)

    Farakos, K.; Koutsoumbas, G.; Surridge, M.; Zoupanos, G.

    1987-06-04

    A four-dimensional gauge theory, where Higgs fields and the corresponding potential appear naturally, is obtained by dimensionally reducing a pure gauge theory over a compact coset space S/R. We show, using an explicit example, that a hierarchy of the scales in the coset space can change the spontaneous symmetry breaking of the four-dimensional gauge theory.

  7. Dimensional reduction and dynamical symmetry breaking

    Energy Technology Data Exchange (ETDEWEB)

    Forgacs, P.; Zoupanos, G.

    1984-11-22

    We present a model in which the electroweak gauge group is broken according to a dynamical scenario based on the chiral symmetry breaking of high colour representations. The dynamical scenario requires also the existence of elementary Higgs fields, which in the present scheme come from the dimensional reduction of a pure gauge theory.

  8. Dimensional reduction and dynamical symmetry breaking

    Energy Technology Data Exchange (ETDEWEB)

    Forgacs, P.; Zoupanos, G. (European Organization for Nuclear Research, Geneva (Switzerland))

    1984-11-22

    We present a model in which the electroweak gauge group is broken according to a dynamical scenario based on the chiral symmetry breaking of high colour representations. The dynamical scenario also requires the existence of elementary Higgs fields, which in the present scheme come from the dimensional reduction of a pure gauge theory.

  9. Dynamical Symmetry Breaking in RN Quantum Gravity

    Directory of Open Access Journals (Sweden)

    A. T. Kotvytskiy

    2011-01-01

    Full Text Available We show that in the RN gravitation model, there is no dynamical symmetry breaking effect in the formalism of the Schwinger-Dyson equation (in flat background space-time. A general formula for the second variation of the gravitational action is obtained from the quantum corrections hμν (in arbitrary background metrics.

  10. Breaking a magnetic zero locus: asymptotic analysis

    OpenAIRE

    Raymond, Nicolas

    2014-01-01

    25 pages; This paper deals with the spectral analysis of the Laplacian in presence of a magnetic field vanishing along a broken line. Denoting by $\\theta$ the breaking angle, we prove complete asymptotic expansions of all the lowest eigenpairs when $\\theta$ goes to $0$. The investigation deeply uses a coherent states decomposition and a microlocal analysis of the eigenfunctions.

  11. Symmetry Breaking for Black-Scholes Equations

    Institute of Scientific and Technical Information of China (English)

    YANG Xuan-Liu; ZHANG Shun-Li; QU Chang-Zheng

    2007-01-01

    Black-Scholes equation is used to model stock option pricing. In this paper, optimal systems with one to four parameters of Lie point symmetries for Black-Scholes equation and its extension are obtained. Their symmetry breaking interaction associated with the optimal systems is also studied. As a result, symmetry reductions and corresponding solutions for the resulting equations are obtained.

  12. A gravity term from spontaneous symmetry breaking

    CERN Document Server

    Moise, Mihai

    2014-01-01

    In this model, the gravity term in the Lagrangean comes from spontaneous symmetry breaking of an additional scalar quadruplet field $\\Upsilon$. The resulting gravitational field is approximate to one of the models of coframe gravity with parameters $\\rho_1 + 4 \\rho_2 = 0$, $\\rho_3 = 0$. This article includes an exact solution of coframe gravity with model parameters $\\rho_1 \

  13. Symmetry and symmetry breaking in particle physics

    OpenAIRE

    Tsou, ST

    1998-01-01

    Symmetry, in particular gauge symmetry, is a fundamental principle in theoretical physics. It is intimately connected to the geometry of fibre bundles. A refinement to the gauge principle, known as ``spontaneous symmetry breaking'', leads to one of the most successful theories in modern particle physics. In this short talk, I shall try to give a taste of this beautiful and exciting concept.

  14. Density Functional Simulation of a Breaking Nanowire

    DEFF Research Database (Denmark)

    Nakamura, A.; Brandbyge, Mads; Hansen, Lars Bruno;

    1999-01-01

    We study the deformation and breaking of an atomic-sized sodium wire using density functional simulations. The wire deforms through sudden atomic rearrangements and smoother atomic displacements. The conductance of the wire exhibits plateaus at integer values in units of 2e(2)/h corresponding...

  15. Supersymmetry Breaking and the Cosmological Constant

    CERN Document Server

    Banks, T

    2014-01-01

    I review three attempts to explain the small value of the cosmological constant, and their connection to SUSY breaking. They are The String Landscape, Supersymmetric Large Extra Dimensions (SLED), and the Holographic Space-time Formalism invented by Fischler and myself.

  16. Adolescent Drug Abuse: Etiological and Treatment Considerations

    Science.gov (United States)

    Amini, Fariboz; And Others

    1976-01-01

    Issues involved in treating adolescent drug abusers and literature describing abuser personality traits are examined. The Youth Service at Langley Porter Institute and the problems encountered and solutions attempted there are discussed. The importance of residential as opposed to outpatient treatment and honesty in staff-patient relationships is…

  17. Iron Deficiency in Adolescents and Young Adults.

    Science.gov (United States)

    Risser, William L.; Risser, Jan M. H.

    1990-01-01

    Reviews the prevalence, natural history, causes, impact on performance, diagnosis, and treatment of iron deficiency in adolescent and young adult athletes. All athletes should be screened and treated. The best diagnosis involves determining serum ferritin and hemoglobin levels. Treatment requires therapeutic doses of oral ferrous iron for several…

  18. Infantile acne treated with oral isotretinoin

    DEFF Research Database (Denmark)

    Miller, Iben Marie; Echeverría, Begoña; Torrelo, Antonio;

    2013-01-01

    In contrast to adolescent acne, infantile acne (IA) is a rare condition with only a limited body of available literature. In this descriptive, retrospective study, we reviewed six cases from 2002 to 2010 treated with oral isotretinoin. The average age of onset was 6.16 months (range 0-21 mos......). Consistent with the previous, limited literature, we found predominantly boys are affected, a predilection for the cheeks, and a polymorphic inflammatory morphology. Two patients had a family history of acne. All cases were successfully and safely treated with oral isotretinoin. The suggested treatment...... of childhood acne is similar to that of adolescents (graded according to the severity of the skin disease and risk of scarring). Oral isotretinoin appears to be an effective and safe treatment for severe IA....

  19. 面部针刺联合壮药面膜治疗青春期湿热质痤疮的疗效评价%Clinical evaluation on treating adolescent acne by facial acupuncture plus traditional mask

    Institute of Scientific and Technical Information of China (English)

    钟江; 李艳艳; 梁金雨; 岳天天

    2014-01-01

    目的:观察面部针刺联合壮药面膜治疗青春期湿热质痤疮的临床疗效。方法:采用随机数字表法把符合标准的100例患者分为两组,各50例。观察组采用针刺面部一定穴位,留针20min,出针后外敷壮药面膜,2d/次,保留20min;对照组取阿达帕林凝胶外用,每晚1次。两组均连续治疗6周。对两组疗效、治疗前后湿热质积分进行比较。结果:两组疗效及湿热质积分比较,差异均有显著性(P<0.05,P<0.01)。结论:面部针刺联合壮药面膜治疗青春期湿热质痤疮能有效降低积分,安全性好,疗效较满意。%Objective: To observe clinical effects of facial acupuncture plus traditional mask on adolescent acne. Methods: In the observation, acupuncture at special acu-point for 20 minutes, then applying traditional mask for 20 minutes for every 2 days; in the control, external applying adapalene gel for every night, all groups were running 6 weeks. Results: The difference of Shi and Re Zhi scores and clinical effects between two groups was significant (P<0.05,P<0.01). Conclusion: Facial acupuncture plus traditional mask can achieved satisfactory effects.

  20. Meanings intrafamilial sexual abuse for female adolescents

    Directory of Open Access Journals (Sweden)

    Juliana Hilario Maranhão

    2014-12-01

    Full Text Available This article came from the monographic study “Resilience and Sexual Violence: a study of adolescents victimized by sexual abuse assistance” (MARANHÃO, 2008, in which was investigated the building resilience in victimized adolescents. Resilience is characterized as overcoming adversity, setting up as something procedural, promoted by the interaction of personal and collective protection, in particular context of risk or social vulnerability. We made the trimming about the meanings and feelings of sexual victimization within the family from the perception of adolescents between 12 and 16 years of age that received care in a Specialized Reference Social Assistance in 2010. The research is qualitative, having as theoretical-methodological referential the Historic-Cultural Theory. Data collection was used by semi-structured interview. We realize that the profile of the victims are set up by females, the beginning of sexual abuse occurred between childhood and preadolescence. The profile of perpetrators are men, adults, acting the role of the stepfather, father and uncle. Despite an abject sense, adolescents could not break the cycle of violence. Friends, extended family, and the work of professionals emerged as support for the redefinition of the abusive relationships.

  1. Influencing Factors of Breaking Capacity of Double-Break Vacuum Circuit Breakers

    Directory of Open Access Journals (Sweden)

    Shengwen Shu

    2013-06-01

    Full Text Available Using a series arrangement of two vacuum interrupters (VIs has been proved to be an effective way of developing higher voltage vacuum circuit breakers (VCBs, which are known as double-break VCBs. The uniform distribution of the transient recovery voltage (TRV across each VI is very critical for the breaking capacity of double-break VCBs. In this paper, the TRV distribution characteristics of double-break VCBs was studied by the synthetic test and the PSCAD/EMTDC simulation based on a vacuum arc interruption model. The results show that the bias of the TRV distribution ratio is caused by the stray capacitance and the imbalanced post arc plasma characteristic in each VI, which is consistent with the theoretical analysis. Moreover, the negative effect of grading capacitors was discussed. The results show that it is advisable to limit the value of grading capacitors to those ranges which can guarantee sufficiently improve the voltage distribution.

  2. Analysis of Melancholy in Alfred Tennyson’s“Break, Break, Break”

    Institute of Scientific and Technical Information of China (English)

    张兰兰

    2012-01-01

      s: As a“Poet Laureate”, Alfred Lord Tennyson has been loved and respected by critics and readers. He is famous not only for his unsurpassed virtuosity, but also the melancholy feeling in his poetry. He excels at penning short lyrics, among which“Break, Break, Break”is one of the representatives. This paper analyzes the melancholy in the poem from different per⁃spectives, the rhetorical device of repetend, the diction and the sound.

  3. The characteristics of serious suicide attempters in Japanese adolescents- comparison study between adolescents and adults

    Directory of Open Access Journals (Sweden)

    Kawashima Yoshitaka

    2012-11-01

    Full Text Available Abstract Background Suicide is the leading cause of death among Japanese adolescents, and they may commit suicide differently from adults. However, there are few studies in medical-based data concerning adolescent patients seriously attempting suicide. We aimed to explore the characteristics of serious suicide attempts in Japanese adolescents, comparing them with those in adults. Methods We investigated adolescents who seriously attempted suicide and were treated at the Critical Care Medical Center (CCMC of Nippon Medical School Hospital between 2000 and 2010, and we compared them with adult suicide attempters treated during 2009. We retrospectively studied medical records and collected clinical data and socio-demographic factors, including age, sex, psychiatric symptoms or diagnosis, methods of suicide attempt, motives for suicide attempt, previous deliberate self-harm, previous psychiatric history, parent loss experience, and previous psychiatric history in the family. Results Adolescent attempters were 15 males and 44 females, 13 to 18 years old (mean 16.39. Adult attempters were 37 males and 65 females, 19 to 79 years old (mean 39.45. In comparison to adult attempters, adolescent attempters were more frequently diagnosed with Borderline Personality Disorder (BPD, had more school problems and parent loss experience, but they had less financial problems. Gender differences between adolescents and adults were examined, and male adolescent attempters were found to be more frequently diagnosed with schizophrenia and had less financial problems than their adult counterparts, while female adolescent attempters were more frequently diagnosed with BPD, had more school problems and parent loss, but they had less previous psychiatric history than their adult counterparts. Conclusions Our findings indicated that adolescent attempters were more frequently diagnosed with BPD and had more school problems and parent loss experience but had less financial

  4. Dynamics of Symmetry Breaking and Tachyonic Preheating

    CERN Document Server

    Felder, G; Greene, P B; Kofman, L A; Linde, Andrei D; Tkachev, Igor I; Felder, Gary; Garcia-Bellido, Juan; Greene, Patrick B.; Kofman, Lev; Linde, Andrei; Tkachev, Igor

    2001-01-01

    We reconsider the old problem of the dynamics of spontaneous symmetry breaking using 3d lattice simulations, and develop a theory of tachyonic preheating, which occurs due to the spinodal instability of the scalar field. Tachyonic preheating is so efficient that symmetry breaking typically completes within a single oscillation of the field distribution as it rolls towards the minimum of its effective potential. As an application of this theory we consider preheating in the hybrid inflation scenario, including SUSY-motivated F-term and D-term inflationary models. We show that preheating in hybrid inflation is typically tachyonic and the stage of oscillations of a homogeneous component of the scalar fields driving inflation ends after a single oscillation. Our results may also be relevant for the theory of the formation of disoriented chiral condensates in heavy ion collisions.

  5. Cosmology of biased discrete symmetry breaking

    Science.gov (United States)

    Gelmini, Graciela B.; Gleiser, Marcelo; Kolb, Edward W.

    1988-01-01

    The cosmological consequences of spontaneous breaking of an approximate discrete symmetry are studied. The breaking leads to formation of proto-domains of false and true vacuum separated by domain walls of thickness determined by the mass scale of the model. The cosmological evolution of the walls is extremely sensitive to the magnitude of the biasing; several scenarios are possible, depending on the interplay between the surface tension on the walls and the volume pressure from the biasing. Walls may disappear almost immediately after they form, or may live long enough to dominate the energy density of the Universe and cause power-law inflation. Limits are obtained on the biasing that characterizes each possible scenario.

  6. Symmetry breaking in non conservative systems

    CERN Document Server

    Martínez-Pérez, N E

    2016-01-01

    We apply Noether's theorem to show how the invariances of conservative systems are broken for nonconservative systems, in the variational formulation of Galley. This formulation considers a conservative action, extended by the inclusion of a time reversed sector and a nonconservative generalized potential. We assume that this potential is invariant under the symmetries of the initial conservative system. The breaking occurs because the time reversed sector requires inverse symmetry transformations, under which the nonconservative potential is not invariant. The resulting violation of the conservation laws is consistent with the equations of motion. We generalize this formulation for fermionic and sypersymmetric systems. In the case of a supersymmetric oscillator, the effect of damping is that the bosonic and fermionic components become different frequencies. Considering that initially the nonconservative action is invariant under supersymmetry, and that the breaking is associated to an instability, this resul...

  7. Metastable spontaneous breaking of N=2 supersymmetry

    Energy Technology Data Exchange (ETDEWEB)

    Légeret, Benoît; Scrucca, Claudio A., E-mail: claudio.scrucca@epfl.ch; Smyth, Paul

    2013-05-24

    We show that contrary to the common lore it is possible to spontaneously break N=2 supersymmetry even in simple theories without constant Fayet–Iliopoulos terms. We consider the most general N=2 supersymmetric theory with one hypermultiplet and one vector multiplet without Fayet–Iliopoulos terms, and show that metastable supersymmetry breaking vacua can arise if both the hyper-Kähler and the special-Kähler geometries are suitably curved. We then also prove that while all the scalars can be massive, the lightest one is always lighter than the vector boson. Finally, we argue that these results also directly imply that metastable de Sitter vacua can exist in N=2 supergravity theories with Abelian gaugings and no Fayet–Iliopoulos terms, again contrary to common lore, at least if the cosmological constant is sufficiently large.

  8. Lyman Break Galaxies in the NGST Era

    CERN Document Server

    Ferguson, H C; Papovich, C; Ferguson, Henry C.; Dickinson, Mark; Papovich, Casey

    2002-01-01

    With SIRTF and NGST in the offing, it is interesting to examine what the stellar populations of z~3 galaxies models imply for the existence and nature of Lyman-break galaxies at higher redshift. To this end, we ``turn back the clock'' on the stellar population models that have been fit to optical and infrared data of Lyman-break galaxies at z~3. The generally young ages (typically 10^8 +- 0.5 yr) of these galaxies imply that their stars were not present much beyond z=4. For smooth star-formation histories SFR(t) and Salpeter IMFs, the ionizing radiation from early star-formation in these galaxies would be insufficient to reionize the intergalactic medium at z~6, and the luminosity density at z~4 would be significantly lower than observed. We examine possible ways to increase the global star-formation rate at higher redshift without violating the stellar-population constraints at z~3.

  9. The Radiative Z2 Breaking Twin Higgs

    CERN Document Server

    Yu, Jiang-Hao

    2016-01-01

    In twin Higgs model, the Higgs boson mass is protected by a $Z_2$ symmetry. The $Z_2$ symmetry needs to be broken either explicitly or spontaneously to obtain misalignment between electroweak and new physics vacua. We propose a novel $Z_2$ breaking mechanism, in which the $Z_2$ is spontaneously broken by radiative corrections to the Higgs potential. Two twin Higgses with different vacua are needed, and vacuum misalignment is realized by opposite but comparable contributions from gauge and Yukawa interactions to the potential. Due to fully radiative symmetry breaking, the Higgs sector is completely determined by twin Higgs vacuum, Yukawa and gauge couplings. There are eight pseudo-Goldstone bosons: the Higgs boson, inert doublet Higgs, and three twin scalars. We show the 125 GeV Higgs mass and constraints from Higgs coupling measurements could be satisfied.

  10. Symmetry Breaking in Neuroevolution: A Technical Report

    CERN Document Server

    Urfalioglu, Onay

    2011-01-01

    Artificial Neural Networks (ANN) comprise important symmetry properties, which can influence the performance of Monte Carlo methods in Neuroevolution. The problem of the symmetries is also known as the competing conventions problem or simply as the permutation problem. In the literature, symmetries are mainly addressed in Genetic Algoritm based approaches. However, investigations in this direction based on other Evolutionary Algorithms (EA) are rare or missing. Furthermore, there are different and contradictionary reports on the efficacy of symmetry breaking. By using a novel viewpoint, we offer a possible explanation for this issue. As a result, we show that a strategy which is invariant to the global optimum can only be successfull on certain problems, whereas it must fail to improve the global convergence on others. We introduce the \\emph{Minimum Global Optimum Proximity} principle as a generalized and adaptive strategy to symmetry breaking, which depends on the location of the global optimum. We apply the...

  11. Collective neutrino oscillations and spontaneous symmetry breaking

    Science.gov (United States)

    Duan, Huaiyu

    2015-08-01

    Neutrino oscillations in a hot and dense astrophysical environment such as a core-collapse supernova pose a challenging, seven-dimensional flavor transport problem. To make the problem even more difficult (and interesting), neutrinos can experience collective oscillations through nonlinear refraction in the dense neutrino medium in this environment. Significant progress has been made in the last decade towards the understanding of collective neutrino oscillations in various simplified neutrino gas models with imposed symmetries and reduced dimensions. However, a series of recent studies seem to have "reset" this progress by showing that these models may not be compatible with collective neutrino oscillations because the latter can break the symmetries spontaneously if they are not imposed. We review some of the key concepts of collective neutrino oscillations by using a few simple toy models. We also elucidate the breaking of spatial and directional symmetries in these models because of collective oscillations.

  12. Collective neutrino oscillations and spontaneous symmetry breaking

    CERN Document Server

    Duan, Huaiyu

    2015-01-01

    Neutrino oscillations in a hot and dense astrophysical environment such as a core-collapse supernova pose a challenging, seven-dimensional flavor transport problem. To make the problem even more difficult (and interesting), neutrinos can experience collective oscillations through nonlinear refraction in the dense neutrino medium in this environment. Significant progress has been made in the last decade towards the understanding of collective neutrino oscillations in various simplified neutrino gas models with imposed symmetries and reduced dimensions. However, a series of recent studies seem to have "reset" this progress by showing that these models may not be compatible with collective neutrino oscillations because the latter can break the symmetries spontaneously if they are not imposed. We review some of the key concepts of collective neutrino oscillations by using a few simple toy models. We also elucidate the breaking of spatial and directional symmetries in these models because of collective oscillation...

  13. Symmetry-breaking oscillations in membrane optomechanics

    Science.gov (United States)

    Wurl, C.; Alvermann, A.; Fehske, H.

    2016-12-01

    We study the classical dynamics of a membrane inside a cavity in the situation where this optomechanical system possesses a reflection symmetry. Symmetry breaking occurs through supercritical and subcritical pitchfork bifurcations of the static fixed-point solutions. Both bifurcations can be observed through variation of the laser-cavity detuning, which gives rise to a boomerang-like fixed-point pattern with hysteresis. The symmetry-breaking fixed points evolve into self-sustained oscillations when the laser intensity is increased. In addition to the analysis of the accompanying Hopf bifurcations we describe these oscillations at finite amplitudes with an ansatz that fully accounts for the frequency shift relative to the natural membrane frequency. We complete our study by following the route to chaos for the membrane dynamics.

  14. The Impact of Gender on the Quality of Life in Patients with Adolescent Idiopathic Scoliosis (A IS) Treated with Brace%不同性别对青少年特发性脊柱侧凸患者支具治疗生存质量评价的影响

    Institute of Scientific and Technical Information of China (English)

    周惠清; 张建新; 林思舜; 柳明忠; 林松庆

    2012-01-01

    目的:检测男女性别不同对青少年特发性脊柱侧凸(AIS)患者支具治疗生存质量评价的影响.方法:将87例支具治疗AIS患者分为2组,男性41例,女性46例,平均随访时间2.5年.2组患者在年龄、随访时间、支具治疗类型、主弯所在节段、以及支具治疗前、治疗后cobb角和Risser征等比较差异无统计学意义(P>0.05),87例患者均填写脊柱侧凸研究会患者问卷-22(SRS-22)量表,比较2组间量表单个维度和单个条目得分的差别.结果:女性治疗满意度维度得分高于男性(P<0.05),女性自我形象/外观维度得分也高于男性(P<0.05);其中自我形象/外观维度的条目4、6、10,以及治疗满意度维度的条目22的得分比较差异有统计学意义(P<0.05);但2组功能/活动度、疼痛和精神健康维度的得分比较差异无统计学意义(P>0.05).结论:性别不同会影响AIS患者支具治疗生存质量的评测结果,评测患者生存质量时需考虑此因素影响.%Objective: To observe the impact of gender on the quality of life in patients with adolescent idiopathic scoliosis (AIS) treated with brace. Methods:87 patients (male 41 cases, female 46) with AIS treated with brace were divided into two groups. The mean follow-up time was 2. 5 years. There was no significant difference (P>0. 05) in age, follow-up time, the type of brace treatment, the main curved located segments, and the Cobb's angle before and after brace treatment and Risser sign in two groups. The questionnaires -22 (SRS-22) scales were filled in for all 87 patients, the scores of dimensions and single items were compared between the two groups. Results: The scores of therapeutic satisfaction in women were higher than that in men (P0. 05) in self-image / appearance of the dimension entries 4,6,10 and the score of therapeutic satisfaction in 22 entries (P0. 05) in function, activity, pain and scores of mental health dimensions in the two group. Conclusions

  15. Dynamical symmetry breaking in quantum field theories

    CERN Document Server

    Miransky, Vladimir A

    1993-01-01

    The phenomenon of dynamical symmetry breaking (DSB) in quantum field theory is discussed in a detailed and comprehensive way. The deep connection between this phenomenon in condensed matter physics and particle physics is emphasized. The realizations of DSB in such realistic theories as quantum chromodynamics and electroweak theory are considered. Issues intimately connected with DSB such as critical phenomenona and effective lagrangian approach are also discussed.

  16. Music and Video Gaming during Breaks

    OpenAIRE

    Liu, Shuyan; Schad, Daniel J; Kuschpel, Maxim S.; Rapp, Michael A.; Heinz, Andreas

    2016-01-01

    Different systems for habitual versus goal-directed control are thought to underlie human decision-making. Working memory is known to shape these decision-making systems and their interplay, and is known to support goal-directed decision making even under stress. Here, we investigated if and how decision systems are differentially influenced by breaks filled with diverse everyday life activities known to modulate working memory performance. We used a within-subject design where young adult...

  17. Supersymmetry breaking made easy, viable, and generic

    CERN Document Server

    Murayama, Hitoshi

    2007-01-01

    The kind of supersymmetry that can be discovered at the LHC must be very much flavor-blind, which used to require very special intelligently designed models of supersymmetry breaking. This led to the pessimism for some in the community that it is not likely for the LHC to discover supersymmetry. I point out that this is not so, because a garden-variety supersymmetric theories actually can do this job.

  18. Wave breaking in tapered holey fibers

    Institute of Scientific and Technical Information of China (English)

    Shuguang Li; Lei Zhang; Bo Fu; Yi Zheng; Ying Han; Xingtao Zhao

    2011-01-01

    We numerically study the propagation of 1-ps laser pulse in three tapered holey fibers (THFs). The curvature indices of the concave, linear, and convex tapers are 2.0, 1.0, and 0.5, respectively. The central wavelength, located in the normal dispersion regime, is 800 nm. The nonlinear coefficient of the THFs increases from the initial 0.095 m-1· W-1 to the final 0.349 m-l·W-1. Wave breaking accompanied by oscillatory structures occurs near pulse edges, and sidelobes appear in the pulse spectrum. With the increase in propagation distance z, the pulse shape becomes broader and the pulse spectrum flattens. A concave THF is advantageous to the generation of wave breaking and enables easier achievement of super fiat spectra at short lengths.%@@ We numerically study the propagation of 1-ps laser pulse in three tapered holey fibers (THFs).The curvature indices of the concave, linear, and convex tapers are 2.0, 1.0, and 0.5, respectively.The central wavelength, located in the normal dispersion regime, is 800 nm.The nonlinear coefficient of the THFs increases from the initial 0.095 m-1.W-1 to the final 0.349 m-1.W-1.Wave breaking accompanied by oscillatory structures occurs near pulse edges, and sidelobes appear in the pulse spectrum.With the increase in propagation distance z, the pulse shape becomes broader and the pulse spectrum flattens.A concave THF is advantageous to the generation of wave breaking and enables easier achievement of super flat spectra at short lengths.

  19. Adjoint string breaking in the pseudoparticle approach

    CERN Document Server

    Szasz, Christian

    2008-01-01

    We apply the pseudoparticle approach to SU(2) Yang-Mills theory and perform a detailed study of the potential between two static charges for various representations. Whereas for charges in the fundamental representation we find a linearly rising confining potential, we clearly observe string breaking, when considering charges in the adjoint representation. We also demonstrate Casimir scaling and compute gluelump masses for different spin and parity. Numerical results are in qualitative agreement with lattice results.

  20. Adolescent and School Health

    Science.gov (United States)

    ... Search The CDC Cancel Submit Search The CDC Adolescent and School Health Note: Javascript is disabled or ... help strengthen their capacity to improve child and adolescent health. More > DASH Home About DASH At A ...

  1. Adolescent health psychology.

    Science.gov (United States)

    Williams, Paula G; Holmbeck, Grayson N; Greenley, Rachel Neff

    2002-06-01

    In this article, a biopsychosocial model of adolescent development is used as an organizing framework for a review of primary, secondary, and tertiary prevention research with adolescent populations. During adolescence many critical health behaviors emerge, affecting future disease outcomes in adulthood. In addition, most of the predominant causes of morbidity and mortality in adolescence are unique to this period of development, indicating that health-focused interventions must be tailored specifically to adolescents. Moreover, it is during adolescence that lifelong patterns of self-management of and adjustment to chronic health conditions are established. Thus, an increased focus on adolescence in health psychology research is important both to improve the health of adolescents per se and to optimize health trajectories into adulthood.

  2. Spontaneous chiral symmetry breaking in the Tayler instability

    CERN Document Server

    Del Sordo, Fabio; Brandenburg, Axel; Mitra, Dhrubaditya

    2011-01-01

    The chiral symmetry breaking properties of the Tayler instability are discussed. Effective amplitude equations are determined in one case. This model has three free parameters that are determined numerically. Comparison with chiral symmetry breaking in biochemistry is made.

  3. A qualitative analysis of adolescent, caregiver, and clinician perceptions of the impact of migraines on adolescents' social functioning.

    Science.gov (United States)

    Donovan, Elizabeth; Mehringer, Stacey; Zeltzer, Lonnie K

    2013-12-01

    Migraines dramatically affect adolescents' quality of life. One area of particular importance is the impact of migraines on adolescents' social functioning. To understand the impact of migraines on adolescents' social functioning from multiple informants, we performed semistructured interviews with adolescents who have migraines, their caregivers, and clinicians who treat adolescents who have migraines. Three major themes related to social functioning were identified from the adolescent interviews: The need to be alone; lack of support from siblings; and the feeling of not being understood by others. The caregiver interviews yielded three main themes related to family functioning: that plans can change quickly; that family life revolves around helping the child with the migraine; and parents' feelings of inadequacy in helping their child. There were two main themes derived from the clinician interviews related to perception of family functioning: the importance of parental involvement; and the role of adolescents' school and social lives in migraine prevention. There are a number of unmet needs among adolescents with recurrent migraine and their families. Interviews with adolescents, caregivers, and clinicians suggest a number of areas for intervention.

  4. A break in the obesity epidemic?

    DEFF Research Database (Denmark)

    Visscher, T L S; Heitmann, B L; Rissanen, A

    2015-01-01

    Recent epidemiologic papers are presenting prevalence data suggesting breaks and decreases in obesity rates. However, before concluding that the obesity epidemic is not increasing anymore, the validity of the presented data should be discussed more thoroughly. We had a closer look into the litera......, focusing on trends in waist circumference rather than BMI leads to a less optimistic conclusion: the public health problem of obesity is still increasing.International Journal of Obesity advance online publication, 22 July 2014; doi:10.1038/ijo.2014.98.......Recent epidemiologic papers are presenting prevalence data suggesting breaks and decreases in obesity rates. However, before concluding that the obesity epidemic is not increasing anymore, the validity of the presented data should be discussed more thoroughly. We had a closer look...... into the literature presented in recent reviews to address the major potential biases and distortions, and to develop insights about how to interpret the presented suggestions for a potential break in the obesity epidemic. Decreasing participation rates, the use of reported rather than measured data and small sample...

  5. Enhanced breaking of heavy quark spin symmetry

    Directory of Open Access Journals (Sweden)

    Feng-Kun Guo

    2014-11-01

    Full Text Available Heavy quark spin symmetry is useful to make predictions on ratios of decay or production rates of systems involving heavy quarks. The breaking of spin symmetry is generally of the order of O(ΛQCD/mQ, with ΛQCD the scale of QCD and mQ the heavy quark mass. In this paper, we will show that a small S- and D-wave mixing in the wave function of the heavy quarkonium could induce a large breaking in the ratios of partial decay widths. As an example, we consider the decays of the ϒ(10860 into the χbJω (J=0,1,2, which were recently measured by the Belle Collaboration. These decays exhibit a huge breaking of the spin symmetry relation were the ϒ(10860 a pure 5S bottomonium state. We propose that this could be a consequence of a mixing of the S-wave and D-wave components in the ϒ(10860. Prediction on the ratio Γ(ϒ(10860→χb0ω/Γ(ϒ(10860→χb2ω is presented assuming that the decay of the D-wave component is dominated by the coupled-channel effects.

  6. Kinematic dynamo, supersymmetry breaking, and chaos

    Science.gov (United States)

    Ovchinnikov, Igor V.; Enßlin, Torsten A.

    2016-04-01

    The kinematic dynamo (KD) describes the growth of magnetic fields generated by the flow of a conducting medium in the limit of vanishing backaction of the fields onto the flow. The KD is therefore an important model system for understanding astrophysical magnetism. Here, the mathematical correspondence between the KD and a specific stochastic differential equation (SDE) viewed from the perspective of the supersymmetric theory of stochastics (STS) is discussed. The STS is a novel, approximation-free framework to investigate SDEs. The correspondence reported here permits insights from the STS to be applied to the theory of KD and vice versa. It was previously known that the fast KD in the idealistic limit of no magnetic diffusion requires chaotic flows. The KD-STS correspondence shows that this is also true for the diffusive KD. From the STS perspective, the KD possesses a topological supersymmetry, and the dynamo effect can be viewed as its spontaneous breakdown. This supersymmetry breaking can be regarded as the stochastic generalization of the concept of dynamical chaos. As this supersymmetry breaking happens in both the diffusive and the nondiffusive cases, the necessity of the underlying SDE being chaotic is given in either case. The observed exponentially growing and oscillating KD modes prove physically that dynamical spectra of the STS evolution operator that break the topological supersymmetry exist with both real and complex ground state eigenvalues. Finally, we comment on the nonexistence of dynamos for scalar quantities.

  7. Dormancy Breaking in Ormosia arborea Seeds

    Directory of Open Access Journals (Sweden)

    Edilma Pereira Gonçalves

    2011-01-01

    Full Text Available Ormosia arborea is a tree species planted in urban areas and used to restore degraded areas. Its seeds are dormant and propagation is difficult. This study compares different dormancy breaking methods and physiological seed quality and seedling production. The seeds were germinated in sand in the laboratory of the Universidade Estadual de Santa Cruz, Ilhéus, Bahia, Brazil. The following dormancy breaking treatments were applied: control (intact seeds, 100°C water immersion; boiling water immersion followed by 24 hours of soaking; scarification with number 100 and number 50 sandpaper opposite from root emergence; sulfuric acid immersion for 1 hour, 50, 45, and 30 minutes. Seed immersion in 100°C and boiling water did not break the dormancy. The study species showed a greater vigor of seedling when its seeds were submitted to treatments associated with tegument rupturing by sandpaper or sulfuric acid. On the other hand, seed scarification with sulfuric acid for 1 hour, 50, 45, and 30 minutes or sandpaper favored seed germination and vigor.

  8. Breaking bad news: a patient's perspective.

    Science.gov (United States)

    Dias, Lauren; Chabner, Bruce A; Lynch, Thomas J; Penson, Richard T

    2003-01-01

    Shortly before his death in 1995, Kenneth B. Schwartz, a cancer patient at Massachusetts General Hospital (MGH), founded The Kenneth B. Schwartz Center at MGH. The Schwartz Center is a nonprofit organization dedicated to supporting and advancing compassionate health care delivery that provides hope to the patient, support to caregivers, and encourages the healing process. The Center sponsors the Schwartz Center Rounds, a monthly multidisciplinary forum where caregivers reflect on important psychosocial issues faced by patients, their families, and their caregivers, and gain insight and support from fellow staff members. Clinicians in the field of oncology are unavoidably forced to break bad news. The Schwartz Center Rounds focuses on issues of communication between patients and their caregivers, one of the most difficult aspects of which is breaking bad news. The invited patient, a woman who had been living with a low-grade cancer for many years, spoke about her experiences both as a person living with cancer and as the daughter of a patient diagnosed with cancer. Her father's suicide, precipitated by being told his diagnosis, puts the horror of receiving bad news into stark relief. She provides a fascinating account of how she proactively adjusted to her diagnosis, and fought for optimal quality of life. This article discusses issues of support, abandonment, and how hope is conveyed, and reviews the literature that informs good clinical practice in breaking bad news.

  9. Improvement of flavor and viscosity in hot and cold break tomato juice and sauce by peel removal.

    Science.gov (United States)

    Mirondo, Rita; Barringer, Sheryl

    2015-01-01

    Tomatoes are typically not peeled before being made into juice but the peels contain enzymes that affect the odor, flavor, and viscosity of the juice. The peels are removed in the finisher, but their presence during the break process may affect quality. Juice was processed from peeled and unpeeled tomatoes using hot or cold break. The juices were pasteurized by high temperature short time (HTST), low temperature long time (LTLT), or with a retort. The control samples were treated with 10% calcium chloride to stop enzymatic activity in the juice. Sauce was made from juice and the tomato products were analyzed for volatiles, color, viscosity, and by sensory. Cold break juice made with peel contained higher levels of some lipoxygenase-, carotenoid-, and amino acid-derived volatiles, than the juice made without peel. Because of the lack of enzyme activity, hot break juices had lower levels of these volatiles and there was no significant difference between hot break juices made with and without peel. CaCl2 -treated and HTST juice had higher levels of most of the volatiles than LTLT, including the lipoxygenase-derived volatiles. The presence of peel produced a significant decrease in the viscosity of the cold break juice and sauce. There was no significant difference in the hue angle, total soluble solids, pH, titratable acidity, and vitamin C for most of the treatments. The texture, flavor, and overall liking of cold break juice made without peel were preferred over cold break juice made with peel whereas the color was less preferred. Between the sauces no significant differences in preference were obtained.

  10. Integral measurement of break-up excitation function using a multiple silicon telescope

    Energy Technology Data Exchange (ETDEWEB)

    Corre, J.M.; Anne, R.; Lewitowicz, M.; Saint-Laurent, M.G. [Grand Accelerateur National d`Ions Lourds (GANIL), 14 - Caen (France); Borcea, C.; Carstoiu, F.; Negoita, F. [Institute of Atomic Physics, Bucharest (Romania); Borrel, V.; Guillemaud-Mueller, D.; Mueller, A.C.; Pougheon, F.; Sorlin, O. [Paris-11 Univ., 91 - Orsay (France). Inst. de Physique Nucleaire; Dlouhy, Z. [NPI, Rez (Czech Republic); Fomichev, A.S.; Lukyanov, S.M.; Penoinzhkevich, Y.E.; Skobelev, N.K. [Joint Inst. for Nuclear Research, Dubna (Russian Federation); Kordyasz, A. [Warsaw Univ. (Poland). Inst. Fizyki Doswiadczalnej

    1994-12-31

    A simple method is proposed for measuring the inclusive break-up excitation function which the experimental device, consisting of a set of successive silicon detectors, serves the double purpose of decreasing the incident beam energy and of detecting and identifying the reaction products. Monte Carlo simulations revealed the merits and the limitations of the method. Finally, experimental data for tritons are treated in order to obtain relevant physical informations (authors). 9 refs., 9 figs.

  11. Healthy breaks: tasty tips for the under fives

    OpenAIRE

    Public Health Agency

    2014-01-01

    Today the Public Health Agency is launching a new resource pack designed to assist nursery schools and playgroups deliver a healthy breaks scheme.All nursery schools and playgroups in Northern Ireland will receive the pack - 'Healthy breaks for pre-school children' - which includes a poster and information leaflets for parents explaining why a healthy break is so important for pre-school children and some tips and ideas for healthy nutritious breaks.Judith Hanvey, Regional Food in Schools Co-...

  12. Adolescence and Mythology

    Science.gov (United States)

    Anastasopoulos, Dimitris; Soumaki, Eugenia; Anagnostopoulos, Dimitris

    2010-01-01

    The article begins with a brief exploration of the various aspects of adolescent's psychic qualities as these are described in Greek mythology. It is argued that myths are an integral part of the way that adolescence is perceived and myths play an important role in adolescents' psychic and external world, as well as in their mythological thinking.…

  13. Demystifying the Adolescent Brain

    Science.gov (United States)

    Steinberg, Laurence

    2011-01-01

    Understanding the nature of brain development in adolescence helps explain why adolescents can vacillate so often between mature and immature behavior. Early and middle adolescence, in particular, are times of heightened vulnerability to risky and reckless behavior because the brain's reward center is easily aroused, but the systems that control…

  14. Effect of physical activities on obese adolescents

    Directory of Open Access Journals (Sweden)

    Sergio Roberto Adriano Prati

    2008-06-01

    Full Text Available The increase in body fat levels associated with the decrease in physical activities in adolescents has been the concern of recent researches because there is a strong correlation between the growing number of early-age obesity cases and the appearance of cardiovascular diseases, diabetes, hypertension, behavior problems and even death when not treated in time. So this study aimed to analyze through a bibliographical investigation some of the factors that cause obesity in adolescents and propose alternative physical activities to help in the treatment and minimize the problem. The analysis showed that programmed, controlled and adequate physical activities, associated with changes in behavior and lifestyle, may revert obesity condition and improve life quality of these adolescents.

  15. Use of Electroconvulsive Therapy in an Adolescent Patient with Catatonia

    OpenAIRE

    Sandeep Grover; Natasha Kate; Gaurav Gupta

    2014-01-01

    There is lot of skepticism about the use of electroconvulsive therapy (ECT) in children and adolescents. However, available literature suggests that use of ECT can be at times life-saving in adolescents, especially those presenting with severe catatonia. We treated a 16-year-old female who presented to us with catatonia with a course of nine ECTs, with which she showed marked improvement. Review of the literature suggests that ECT should be considered as the second line treatment in the manag...

  16. Ethics and risk management in administrative child and adolescent psychiatry.

    Science.gov (United States)

    Sondheimer, Adrian

    2010-01-01

    This article examines ethics (the philosophic study of "doing the right thing") and risk management (the practice that seeks to manage the likelihood of "doing the wrong thing") and the relationship between them in the context of administrative child and adolescent psychiatry. Issues that affect child and adolescent psychiatrists who manage staff and business units and clinical practitioners who treat and manage individual patients are addressed. Malpractice, budgeting, credentialing, boundaries, assessment, documentation, treatment, research, dangerousness, and confidentiality are among the topics reviewed.

  17. Use of electroconvulsive therapy in an adolescent patient with catatonia

    Directory of Open Access Journals (Sweden)

    Sandeep Grover

    2014-01-01

    Full Text Available There is lot of skepticism about the use of electroconvulsive therapy (ECT in children and adolescents. However, available literature suggests that use of ECT can be at times life-saving in adolescents, especially those presenting with severe catatonia. We treated a 16-year-old female who presented to us with catatonia with a course of nine ECTs, with which she showed marked improvement. Review of the literature suggests that ECT should be considered as the second line treatment in the management of catatonia in adolescents.

  18. Adolescent substance use and unplanned pregnancy: strategies for risk reduction.

    Science.gov (United States)

    Connery, Hilary Smith; Albright, Brittany B; Rodolico, John M

    2014-06-01

    Substance use among adolescents increases the risk of unplanned pregnancies, which then increases the risk of fetal exposure to addictive, teratogenic substances. Specific interventions are necessary to target pregnancy planning and contraception among reproductive-age substance users. Screening for substance use using the CRAFFT is recommended in all health care settings treating adolescent patients. Screening for tobacco and nicotine use is also recommended along with the provision of smoking cessation interventions. Using motivational interviewing style and strategies is recommended to engage adolescents in discussions related to reducing substance use, risky sexual behavior, and probability of unplanned pregnancy or late-detection pregnancy.

  19. Adolescent boys and girls with behavioral disorders in residential homes: A camera-glasses study

    Directory of Open Access Journals (Sweden)

    Alexander Wettstein

    2013-03-01

    Full Text Available Children and adolescents with behavioral disorders are often referred to residential homes. These homes cater and treat socially disadvantaged adolescents with a history of deviant behavior. This study investigated the environment of eight adolescents in these residential homes and four non-aggressive adolescents living with their families. The daily activities were recorded by using camera-glasses attached to the subject. These activities took place in school, leisure time, family and residential homes. Other additional methods were used to investigate the perception and experience of these adolescents. The results of this study indicate that the adolescents in residential homes have a smaller living space in contrast to the non-aggressive adolescents. They also have less close relationships and fewer interactions with their peers. Moreover they have more conflicts and show more often aggressive behavior and they are more often victims of aggression.

  20. Spontaneous symmetry breaking in a classical particle

    CERN Document Server

    Sánchez, L A; Sanchez, Luis Alberto; Mahecha, Jorge

    2003-01-01

    Due to the fact that only matter fields have phase, frequently is believed that the gauge principle can induce gauge fields only in quantum systems. But this is not necessary. This paper, of pedagogical scope, presents a classical system constituted by a particle in a classical potential, which is used as a model to illustrate the gauge principle and the spontaneous symmetry breaking. Those concepts appear in the study of second order phase transitions. Ferroelectricity, ferromagnetism, superconductivity, plasmons in a free electron gas, and the mass of vector bosons in the gauge field Yang-Mills theories, are some of the phenomena in which these transitions occur.

  1. Phenomenology of symmetry breaking from extra dimensions

    CERN Document Server

    Alfaro, J; Gavela-Legazpi, Maria Belen; Rigolin, S; Salvatori, M

    2007-01-01

    Motivated by the electroweak hierarchy problem, we study the symmetry breaking pattern induced by a background magnetic flux living on extra dimensions, with the four-dimensional scalar fields being gauge boson components in full space. For SU(N) and two compact, toroidal, extra dimensions, we determine analytically the possible field configurations of stable vacua and their symmetries. From the four-dimensional point of view, the system responds dynamically to the magnetic background by an infinite chain of vacuum expectation values so as to reach a stable vacuum. The equivalence between flux compactification and constant boundary conditions - either Scherk-Schwarz or twisted - is established.

  2. Chiral symmetry breaking in continuum QCD

    Science.gov (United States)

    Mitter, Mario; Pawlowski, Jan M.; Strodthoff, Nils

    2015-03-01

    We present a quantitative analysis of chiral symmetry breaking in two-flavor continuum QCD in the quenched limit. The theory is set up at perturbative momenta, where asymptotic freedom leads to precise results. The evolution of QCD towards the hadronic phase is achieved by means of dynamical hadronization in the nonperturbative functional renormalization group approach. We use a vertex expansion scheme based on gauge-invariant operators and discuss its convergence properties and the remaining systematic errors. In particular, we present results for the quark propagator, the full tensor structure and momentum dependence of the quark-gluon vertex, and the four-Fermi scatterings.

  3. Electroweak symmetry breaking beyond the Standard Model

    Indian Academy of Sciences (India)

    Gautam Bhattacharyya

    2012-10-01

    In this paper, two key issues related to electroweak symmetry breaking are addressed. First, how fine-tuned different models are that trigger this phenomenon? Second, even if a light Higgs boson exists, does it have to be necessarily elementary? After a brief introduction, the fine-tuning aspects of the MSSM, NMSSM, generalized NMSSM and GMSB scenarios shall be reviewed, then the little Higgs, composite Higgs and the Higgsless models shall be compared. Finally, a broad overview will be given on where we stand at the end of 2011.

  4. Breaking Barriers in Polymer Additive Manufacturing

    Energy Technology Data Exchange (ETDEWEB)

    Love, Lonnie J [ORNL; Duty, Chad E [ORNL; Post, Brian K [ORNL; Lind, Randall F [ORNL; Lloyd, Peter D [ORNL; Kunc, Vlastimil [ORNL; Peter, William H [ORNL; Blue, Craig A [ORNL

    2015-01-01

    Additive Manufacturing (AM) enables the creation of complex structures directly from a computer-aided design (CAD). There are limitations that prevent the technology from realizing its full potential. AM has been criticized for being slow and expensive with limited build size. Oak Ridge National Laboratory (ORNL) has developed a large scale AM system that improves upon each of these areas by more than an order of magnitude. The Big Area Additive Manufacturing (BAAM) system directly converts low cost pellets into a large, three-dimensional part at a rate exceeding 25 kg/h. By breaking these traditional barriers, it is possible for polymer AM to penetrate new manufacturing markets.

  5. String Breaking in Four Dimensional Lattice QCD

    CERN Document Server

    Duncan, A; Thacker, H

    2001-01-01

    Virtual quark pair screening leads to breaking of the string between fundamental representation quarks in QCD. For unquenched four dimensional lattice QCD, this (so far elusive) phenomenon is studied using the recently developed truncated determinant algorithm (TDA). The dynamical configurations were generated on an Athlon 650 MHz PC. Quark eigenmodes up to 420 MeV are included exactly in these TDA studies performed at low quark mass on large coarse (but O($a^2$) improved) lattices. A study of Wilson line correlators in Coulomb gauge extracted from an ensemble of 1000 two-flavor dynamical configurations reveals evidence for flattening of the string tension at distances R $\\geq$ approximately 1 fm.

  6. On inflation, cosmological constant, and SUSY breaking

    CERN Document Server

    Linde, Andrei

    2016-01-01

    We consider a broad class of inflationary models of two unconstrained chiral superfields, the stabilizer $S$ and the inflaton $\\Phi$, which can describe inflationary models with nearly arbitrary potentials. These models include, in particular, the recently introduced theories of cosmological attractors, which provide an excellent fit to the latest Planck data. We show that by adding to the superpotential of the fields $S$ and $\\Phi$ a small term depending on a nilpotent chiral superfield $P$ one can break SUSY and introduce a small cosmological constant without affecting main predictions of the original inflationary scenario.

  7. SU(3) flavour breaking and baryon structure

    Energy Technology Data Exchange (ETDEWEB)

    Cooke, A.N.; Horsley, R. [Edinburgh Univ. (United Kingdom). School of Physics and Astronomy; Nakamura, Y. [RIKEN Advanced Institute for Computational Science, Kobe, Hyogo (Japan); Pleiter, D. [Forschungszentrum Juelich GmbH (Germany). Juelich Supercomputing Centre (JSC); Regensburg Univ. (Germany). Institut fuer Theoretische Physik; Rakow, P.E.L. [Liverpool Univ. (United Kingdom). Theoretical Physics Div.; Shanahan, P.; Zanotti, J.M. [Adelaide Univ., SA (Australia). CSSM, School of Chemistry and Physics; Schierholz, G. [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Stueben, H. [Hamburg Univ. (Germany). Regionales Rechenzentrum; Collaboration: QCDSF/UKQCD Collaboration

    2013-11-15

    We present results from the QCDSF/UKQCD collaboration for hyperon electromagnetic form factors and axial charges obtained from simulations using N{sub f}=2+1 flavours of O(a)-improved Wilson fermions. We also consider matrix elements relevant for hyperon semileptonic decays. We find flavour-breaking effects in hyperon magnetic moments which are consistent with experiment, while our results for the connected quark spin content indicates that quarks contribute more to the spin of the {Xi} baryon than they do to the proton.

  8. De Sitter Uplift with Dynamical Susy Breaking

    CERN Document Server

    Retolaza, Ander

    2015-01-01

    We propose the use of D-brane realizations of Dynamical Supersymmetry Breaking (DSB) gauge sectors as sources of uplift in compactifications with moduli stabilization onto de Sitter vacua. This construction is fairly different from the introduction of anti D-branes, yet allows for tunably small contributions to the vacuum energy via their embedding into warped throats. The idea is explicitly exemplified by the embedding of the 1-family $SU(5)$ DSB model in a local warped throat with fluxes, which we discuss in detail in terms of orientifolds of dimer diagrams.

  9. De Sitter uplift with Dynamical Susy Breaking

    Science.gov (United States)

    Retolaza, Ander; Uranga, Angel

    2016-04-01

    We propose the use of D-brane realizations of Dynamical Supersymmetry Breaking (DSB) gauge sectors as sources of uplift in compactifications with moduli stabilization onto de Sitter vacua. This construction is fairly different from the introduction of anti D-branes, yet allows for tunably small contributions to the vacuum energy via their embedding into warped throats. The idea is explicitly exemplified by the embedding of the 1-family SU(5) DSB model in a local warped throat with fluxes, which we discuss in detail in terms of orientifolds of dimer diagrams.

  10. Breaking of Cooper pairs in 108Pd

    Science.gov (United States)

    Rahmatinejad, A.; Kakavand, T.; Razavi, R.

    2016-04-01

    In this paper, breaking of Cooper pairs in 108Pd is investigated within the canonical ensemble framework and the BCS model. Our results show an evidence of two phase transitions, which are related to neutron and proton systems. Also, with consideration of pairing interaction, the role of neutron and proton systems in entropy, spin cutoff parameter and as a result in the moment of inertia are investigated. The results show minor role for the proton system at low temperatures and approximately equal roles for both neutron and proton systems after the critical temperature. Good agreement was observed between obtained results and the experimental data.

  11. Dynamical Supersymmetry Breaking Why and How

    CERN Document Server

    Poppitz, E R

    1998-01-01

    This theoretical review is intended to give non-theorists a flavor of the ideas driving the current efforts to experimentally find supersymmetry. We discuss the main reasons behind the expectation that supersymmetry may be "just around the corner" and may be discovered in the near future. We use simple quantum-mechanical examples to illustrate the concept---and the power---of supersymmetry, the possible ways to break supersymmetry, and the dynamical generation of small scales. We then describe how this theoretical machinery helps shape our perception of what physics beyond the electroweak scale might be.

  12. Cascading Multicriticality in Nonrelativistic Spontaneous Symmetry Breaking

    CERN Document Server

    Griffin, Tom; Horava, Petr; Yan, Ziqi

    2015-01-01

    Without Lorentz invariance, spontaneous global symmetry breaking can lead to multicritical Nambu-Goldstone modes with a higher-order low-energy dispersion $\\omega\\sim k^n$ ($n=2,3,\\ldots$), whose naturalness is protected by polynomial shift symmetries. Here we investigate the role of infrared divergences and the nonrelativistic generalization of the Coleman-Hohenberg-Mermin-Wagner (CHMW) theorem. We find novel cascading phenomena with large hierarchies between the scales at which the value of $n$ changes, leading to an evasion of the "no-go" consequences of the relativistic CHMW theorem.

  13. Cosmological SUSY Breaking and the Pyramid Schemes

    CERN Document Server

    Banks, T

    2014-01-01

    I review the ideas of holographic space-time (HST), Cosmological SUSY breaking (CSB), and the Pyramid Schemes, which are the only known models of Tera-scale physics consistent with CSB, current particle data, and gauge coupling unification. There is considerable uncertainty in the estimate of the masses of supersymmetric partners of the standard model particles, but the model predicts that the gluino is probably out of reach of the LHC, squarks may be in reach, and the NLSP is a right handed slepton, which should be discovered soon.

  14. Tree Level Mediation of Supersymmetry Breaking

    Energy Technology Data Exchange (ETDEWEB)

    Nardecchia, Marco, E-mail: marco.nardecchia@sissa.it [SISSA/ISAS and INFN, I-34013 Trieste (Italy)

    2010-11-01

    We propose a new scheme in which supersymmetry breaking is communicated to the MSSM sfermions by GUT gauge interactions at the tree level. The (positive) contribution of MSSM fields to Str(M{sup 2}) is automatically compensated by a (negative) contribution from heavy fields. Sfermion masses are flavour universal, thus solving the supersymmetric flavour problem. In the simplest SO(10) embedding, the ratio of different sfermion masses is predicted and differs from mSugra and other schemes, thus making this framework testable at the LHC. Gaugino masses are generated at the loop level but enhanced by model dependent factors.

  15. Insight into Phenomena of Symmetry Breaking Bifurcation

    Institute of Scientific and Technical Information of China (English)

    FANG Tong; ZHANG Ying

    2008-01-01

    @@ We show that symmetry-breaking (SB) bifurcation is just a transition of different forms of symmetry, while still preserving system's symmetry. SB bifurcation always associates with a periodic saddle-node bifurcation, identifiable by a zero maximum of the top Lyapunov exponent of the system. In addition, we show a significant phase portrait of a newly born periodic saddle and its stable and unstable invariant manifolds, together with their neighbouring flow pattern of Poincaré mapping points just after the periodic saddle-node bifurcation, thus gaining an insight into the mechanism of SB bifurcation.

  16. Parity Breaking Medium and Squeeze Operators

    CERN Document Server

    Andrianov, A A; Soldati, R

    2016-01-01

    The transition between a Minkowski space region and a parity breaking medium domain is thoroughly discussed. The requirement of continuity of the field operator content across the separating boundary of the two domains leads to Bogolyubov transformations, squeezed pairs states and squeeze operators that turn out to generate a functional SU(2) algebra. According to this algebraic approach, the reflection and transmission probability amplitude across the separating boundary are computed. The suitable generalization of the well known Sauter-Schwinger-Nikishov formula to the emission or absorption of squeezed pairs out of the vacuum is obtained.

  17. Primary prevention of adolescent pregnancy.

    Science.gov (United States)

    Schinke, S P; Blythe, B J; Gilchrist, L D; Burt, G A

    1981-01-01

    Teenage pregnancy is associated with many health, emotional and socioeconomic problems including higher rates of anemia, labor complications, mortality, legal and social struggles and hhigher divorce rates. Professional social workers need strategies to help teenagers avoid early, unwanted pregnancy. This paper offers promising experential and research backing for a primary prevention group work strategy for all adolescents. Social and health programs overlook educational, cognitive anc interpersonal factors biasing youths' ability to comprehend and regulate contraception. Primary prevention to assist adolescents in thinking analytically about their sexual behavior must stress problem solving and decision-making as well as facts about human reproduction and birth control. To implement decisions, youths also need interpersonal communication skills. Small groups are ideal for delivering cognitive-behavioral primary prevention. This approach is based on the premise that youths become pregnant not because of a lack of relevant information, but because they lack cognitive and behavioral skills necessary to use information. Group work involving role-playing helps develop communication skills. Results from 2 field studies describe short-term and longitudinal benefits of the prevention strategy. Professionals can reach significant numbers of youth in this way. By treating sexual issues and the risk of pregnancy as normal in adolescence, social workers can introduce information and pertinent skills to all teenagers. No one is singled out as deviant and the group format enables young people to discuss taboo topics, discovering what the norms are and gradually learning how to deal with peers, family members, techers and others. Adolescents in primary prevention groups gained knowledge, cognitive skills and communication acumen. Improved attitudes toward family planning, increased regular contraception and less unsafe sex resulted from this cognitive-behavioral approach

  18. Differential behavioural and neurochemical outcomes from chronic paroxetine treatment in adolescent and adult rats: a model of adverse antidepressant effects in human adolescents?

    Science.gov (United States)

    Karanges, Emily; Li, Kong M; Motbey, Craig; Callaghan, Paul D; Katsifis, Andrew; McGregor, Iain S

    2011-05-01

    Selective serotonin reuptake inhibitor use is associated with increased risk of suicidal ideation in adolescent humans, yet the neuropharmacological basis of this phenomenon is unknown. Consequently, we examined the behavioural and neurochemical effects of chronic paroxetine (PRX) treatment in adult and adolescent rats. Rats received PRX in their drinking water (target dose 10 mg/kg) for 22 d, during which time they were assessed for depression- and anxiety-like behaviours. Subsequent ex-vivo analyses examined serum PRX concentrations, striatal neurotransmitter content, and regional serotonin and dopamine transporter (SERT, DAT) binding density. After 11-12 d treatment, PRX-treated adolescent rats showed a significant inhibition of social interaction while adults were unaffected. After 19-20 d treatment, adolescents failed to show an antidepressant-like effect of PRX treatment on the forced swim test (FST), while PRX-treated adults showed a typical decrease in immobility and increase in swimming. Two PRX-treated adolescents died unexpectedly after the FST suggesting a compromised response to physical stress. Despite their greater apparent adverse reaction to the drug, adolescents had significantly lower plasma PRX than adults at day 22 of treatment. Chronic PRX treatment had similar effects in adults and adolescents on striatal 5-HT (unchanged relative to controls) and 5-HIAA levels (decreased), while markers of dopaminergic function (DOPAC, HVA, DA turnover) were increased in adults only. SERT density was up-regulated in the amygdala in PRX-treated adolescents only while DAT density in the nucleus accumbens was down-regulated only in PRX-treated adults. These data suggest that the immature rat brain responds differently to PRX and that this might be of use in modelling the atypical response of human adolescents to antidepressants. The age-specific PRX-induced changes in dopaminergic markers and SERT and DAT binding provide clues as to the neural mechanisms

  19. Advances in understanding and treating ADHD

    Directory of Open Access Journals (Sweden)

    Hendricks Kaitlin

    2011-06-01

    Full Text Available Abstract Attention deficit hyperactivity disorder (ADHD is a neurocognitive behavioral developmental disorder most commonly seen in childhood and adolescence, which often extends to the adult years. Relative to a decade ago, there has been extensive research into understanding the factors underlying ADHD, leading to far more treatment options available for both adolescents and adults with this disorder. Novel stimulant formulations have made it possible to tailor treatment to the duration of efficacy required by patients, and to help mitigate the potential for abuse, misuse and diversion. Several new non-stimulant options have also emerged in the past few years. Among these, cognitive behavioral interventions have proven popular in the treatment of adult ADHD, especially within the adult population who cannot or will not use medications, along with the many medication-treated patients who continue to show residual disability.

  20. How Is LAM Treated?

    Science.gov (United States)

    ... no cure for LAM, doctors treat LAM with sirolimus (rapamycin), a medicine that stabilizes lung function, treats an ... new treatment recommendations. Medicines Your doctor may prescribe sirolimus (rapamycin) to treat your condition, or bronchodilators or ...

  1. Chiral Gauge Dynamics and Dynamical Supersymmetry Breaking

    Energy Technology Data Exchange (ETDEWEB)

    Poppitz, Erich; /Toronto U.; Unsal, Mithat; /SLAC /Stanford U.

    2009-05-07

    We study the dynamics of a chiral SU(2) gauge theory with a Weyl fermion in the I = 3/2 representation and of its supersymmetric generalization. In the former, we find a new and exotic mechanism of confinement, induced by topological excitations that we refer to as magnetic quintets. The supersymmetric version was examined earlier in the context of dynamical supersymmetry breaking by Intriligator, Seiberg, and Shenker, who showed that if this gauge theory confines at the origin of moduli space, one may break supersymmetry by adding a tree level superpotential. We examine the dynamics by deforming the theory on S{sup 1} x R{sup 3}, and show that the infrared behavior of this theory is an interacting CFT at small S{sup 1}. We argue that this continues to hold at large S{sup 1}, and if so, that supersymmetry must remain unbroken. Our methods also provide the microscopic origin of various superpotentials in SQCD on S{sup 1} x R{sup 3}--which were previously obtained by using symmetry and holomorphy--and resolve a long standing interpretational puzzle concerning a flux operator discovered by Affleck, Harvey, and Witten. It is generated by a topological excitation, a 'magnetic bion', whose stability is due to fermion pair exchange between its constituents. We also briefly comment on composite monopole operators as leading effects in two dimensional antiferromagnets.

  2. Large-field inflation and supersymmetry breaking

    Energy Technology Data Exchange (ETDEWEB)

    Buchmueller, Wilfried; Wieck, Clemens [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Dudas, Emilian; Heurtier, Lucien [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Ecole Polytechnique, Palaiseau (France). CPht

    2014-07-15

    Large-field inflation is an interesting and predictive scenario. Its non-trivial embedding in supergravity was intensively studied in the recent literature, whereas its interplay with supersymmetry breaking has been less thoroughly investigated. We consider the minimal viable model of chaotic inflation in supergravity containing a stabilizer field, and add a Polonyi field. Furthermore, we study two possible extensions of the minimal setup. We show that there are various constraints: first of all, it is very hard to couple an O'Raifeartaigh sector with the inflaton sector, the simplest viable option being to couple them only through gravity. Second, even in the simplest model the gravitino mass is bounded from above parametrically by the inflaton mass. Therefore, high-scale supersymmetry breaking is hard to implement in a chaotic inflation setup. As a separate comment we analyze the simplest chaotic inflation construction without a stabilizer field, together with a supersymmetrically stabilized Kaehler modulus. Without a modulus, the potential of such a model is unbounded from below. We show that a heavy modulus cannot solve this problem.

  3. The Masses of Lyman Break Galaxies

    Science.gov (United States)

    Primack, Joel R.; Wechsler, Risa H.; Somerville, Rachel S.

    Data on galaxies at high redshift, identified by the Lyman-break photometric technique, can teach us about how galaxies form and evolve. The stellar masses and other properties of such Lyman break galaxies (LBGs) depend sensitively on the details of star formation. In this paper we consider three different star formation prescriptions, and use semi-analytic methods applied to the now-standard ΛCDM theory of hierarchical structure formation to show how these assumptions about star formation affect the predicted masses of the stars in these galaxies and the masses of the dark matter halos that host them. We find that, within the rather large uncertainties, recent estimates of the stellar masses of LBGs from multi-color photometry are consistent with the predictions of all three models. However, the estimated stellar masses are more consistent with the predictions of two of the models in which star formation is accelerated at high redshifts z ≳ 3, and of these models the one in which many of the LBGs are merger-driven starbursts is also more consistent with indications that many high redshift galaxies are gas rich. The clustering properties of LBGs have put some constraints on the masses of their host halos, but due to similarities in the halo occupation of the three models we consider and degeneracies between model parameters, current constraints are not yet sufficient to distinguish between realistic models.

  4. The Masses of Lyman Break Galaxies

    CERN Document Server

    Primack, Joel R; Somerville, R S; Primack, Joel R.; Wechsler, Risa H.; Somerville, Rachel S.

    2001-01-01

    Data on galaxies at high redshift, identified by the Lyman-break photometric technique, can teach us about how galaxies form and evolve. The stellar masses and other properties of such Lyman break galaxies (LBGs) depend sensitively on the details of star formation. In this paper we consider three different star formation prescriptions, and use semi-analytic methods applied to the now-standard $\\Lambda$CDM theory of hierarchical structure formation to show how these assumptions about star formation affect the predicted masses of the stars in these galaxies and the masses of the dark matter halos that host them. We find that, within the rather large uncertainties, recent estimates of the stellar masses of LBGs from multi-color photometry are consistent with the predictions of all three models. However, the estimated stellar masses are more consistent with the predictions of two of the models in which star formation is accelerated at high redshifts $z\\gsim3$, and of these models the one in which many of the LBGs...

  5. Chiral symmetry breaking, instantons, and monopoles

    CERN Document Server

    Di Giacomo, Adriano

    2015-01-01

    The purpose of this study is to show that monopoles induce the chiral symmetry breaking. In order to indicate the evidence, we add one pair of monopoles with magnetic charges to the quenched SU(3) configurations by a monopole creation operator, and investigate the propaties of the chiral symmetry breaking using the Overlap fermion. We show that instantons are created by the monopoles. The pseudoscalar meson mass and decay constant are computed from the correlation functions, and the renormalization constant $Z_{S}$ is determined by the non perturbative method. The renormalization group invariant chiral condensate in $\\overline{\\mbox{MS}}$-scheme at 2 [GeV] is evaluated by the Gell-Mann-Oakes-Renner formula, and the random matrix theory. Finally, we estimate the renormalization group invariant quark masses $\\bar{m} = (m_{u} + m_{d})/2$, and $m_{s}$ in $\\overline{\\mbox{MS}}$-scheme at 2 [GeV]. The preliminary results indicate that the chiral condensate decreases and the quark masses become slightly heavy by inc...

  6. Generalized Soft Breaking Leverage for the MSSM

    CERN Document Server

    Ün, Cem Salih; Kerman, Saime; Solmaz, Levent

    2014-01-01

    In this work we study implications of additional non-holomorphic soft breaking terms (mu', A'_t, A'_b and A'_tau$) on the MSSM phenomenology. By respecting the existing bounds on the mass measurements and restrictions coming from certain B-decays, we probe reactions of the MSSM to these additional soft breaking terms. We provide examples in which some slightly excluded solutions of the MSSM can be made to be consistent with the current experimental results. During this, even after applying additional fine-tuning constraints the non-holomorphic terms are allowed to be as large as hundreds of GeV. Such terms prove that they are capable of enriching the phenomenology and varying the mass spectra of the MSSM heavily, with a reasonable amount of fine-tuning. We observe that higgsinos, the lightest stop, the heavy Higgs boson states A, H, charged H, sbottom and stau exhibit the highest sensitivity to the new terms. We also show how the light stop can become nearly degenerate with top quark using these non-holomorph...

  7. Chip breaking system for automated machine tool

    Science.gov (United States)

    Arehart, Theodore A.; Carey, Donald O.

    1987-01-01

    The invention is a rotary selectively directional valve assembly for use in an automated turret lathe for directing a stream of high pressure liquid machining coolant to the interface of a machine tool and workpiece for breaking up ribbon-shaped chips during the formation thereof so as to inhibit scratching or other marring of the machined surfaces by these ribbon-shaped chips. The valve assembly is provided by a manifold arrangement having a plurality of circumferentially spaced apart ports each coupled to a machine tool. The manifold is rotatable with the turret when the turret is positioned for alignment of a machine tool in a machining relationship with the workpiece. The manifold is connected to a non-rotational header having a single passageway therethrough which conveys the high pressure coolant to only the port in the manifold which is in registry with the tool disposed in a working relationship with the workpiece. To position the machine tools the turret is rotated and one of the tools is placed in a material-removing relationship of the workpiece. The passageway in the header and one of the ports in the manifold arrangement are then automatically aligned to supply the machining coolant to the machine tool workpiece interface for breaking up of the chips as well as cooling the tool and workpiece during the machining operation.

  8. Repair of DNA Double-Strand Breaks

    Science.gov (United States)

    Falk, Martin; Lukasova, Emilie; Kozubek, Stanislav

    The genetic information of cells continuously undergoes damage induced by intracellular processes including energy metabolism, DNA replication and transcription, and by environmental factors such as mutagenic chemicals and UV and ionizing radiation. This causes numerous DNA lesions, including double strand breaks (DSBs). Since cells cannot escape this damage or normally function with a damaged genome, several DNA repair mechanisms have evolved. Although most "single-stranded" DNA lesions are rapidly removed from DNA without permanent damage, DSBs completely break the DNA molecule, presenting a real challenge for repair mechanisms, with the highest risk among DNA lesions of incorrect repair. Hence, DSBs can have serious consequences for human health. Therefore, in this chapter, we will refer only to this type of DNA damage. In addition to the biochemical aspects of DSB repair, which have been extensively studied over a long period of time, the spatio-temporal organization of DSB induction and repair, the importance of which was recognized only recently, will be considered in terms of current knowledge and remaining questions.

  9. Spontaneous spherical symmetry breaking in atomic confinement

    CERN Document Server

    Sveshnikov, K

    2016-01-01

    The effect of spontaneous breaking of initial SO(3) symmetry is shown to be possible for an H-like atom in the ground state, when it is confined in a spherical box under general boundary conditions of "not going out" through the box surface (i.e. third kind or Robin's ones), for a wide range of physically reasonable values of system parameters. The reason is that such boundary conditions could yield a large magnitude of electronic wavefunction in some sector of the box boundary, what in turn promotes atomic displacement from the box center towards this part of the boundary, and so the underlying SO(3) symmetry spontaneously breaks. The emerging Goldstone modes, coinciding with rotations around the box center, restore the symmetry by spreading the atom over a spherical shell localized at some distances from the box center. Atomic confinement inside the cavity proceeds dynamically -- due to the boundary condition the deformation of electronic wavefunction near the boundary works as a spring, that returns the at...

  10. Golden Probe of Electroweak Symmetry Breaking

    Science.gov (United States)

    Chen, Yi; Lykken, Joe; Spiropulu, Maria; Stolarski, Daniel; Vega-Morales, Roberto

    2016-12-01

    The ratio of the Higgs couplings to W W and Z Z pairs, λW Z, is a fundamental parameter in electroweak symmetry breaking as well as a measure of the (approximate) custodial symmetry possessed by the gauge boson mass matrix. We show that Higgs decays to four leptons are sensitive, via tree level or one-loop interference effects, to both the magnitude and, in particular, overall sign of λW Z. Determining this sign requires interference effects, as it is nearly impossible to measure with rate information. Furthermore, simply determining the sign effectively establishes the custodial representation of the Higgs boson. We find that h →4 ℓ (4 ℓ≡2 e 2 μ , 4 e , 4 μ ) decays have excellent prospects of directly establishing the overall sign at a high luminosity 13 TeV LHC. We also examine the ultimate LHC sensitivity in h →4 ℓ to the magnitude of λW Z. Our results are independent of other measurements of the Higgs boson couplings and, in particular, largely free of assumptions about the top quark Yukawa couplings which also enter at one loop. This makes h →4 ℓ a unique and independent probe of electroweak symmetry breaking and custodial symmetry.

  11. D-branes, Supersymmetry Breaking, and Neutrinos

    CERN Document Server

    Seo, Jihye

    2010-01-01

    This thesis studies meta- and exactly stable supersymmetry breaking mechanisms in heterotic and type IIB string theories and constructs an F-theory Grand Unified Theory model for neutrino physics in which neutrino mass is determined by the supersymmetry breaking mechanism. Focussing attention on heterotic string theory compactified on a 4-torus, stability of non-supersymmetric states is studied. A non-supersymmetric state with robust stability is constructed, and its exact stability is proven in a large region of moduli space of T^4 against all the possible decay mechanisms allowed by charge conservation. Using string-string duality, the results are interpreted in terms of Dirichlet-branes in type IIA string theory compactified on an orbifold limit of a K3 surface. In type IIB string theory, metastable and exactly stable non-supersymmetric systems are constructed using D-branes and Calabi-Yau geometry. Branes and anti-branes wrap rigid and separate 2-spheres inside a non-compact Calabi-Yau three-fold: supersy...

  12. Vitamin D deficiency in adolescents.

    Science.gov (United States)

    Soliman, Ashraf T; De Sanctis, Vincenzo; Elalaily, Rania; Bedair, Said; Kassem, Islam

    2014-11-01

    The prevalence of severe vitamin D deficiency (VDD) in adolescents is variable but considerably high in many countries, especially in Middle-east and Southeast Asia. Different factors attribute to this deficiency including lack of sunlight exposure due to cultural dress codes and veiling or due to pigmented skin, and less time spent outdoors, because of hot weather, and lower vitamin D intake. A potent adaptation process significantly modifies the clinical presentation and therefore clinical presentations may be subtle and go unnoticed, thus making true prevalence studies difficult. Adolescents with severe VDD may present with vague manifestations including pain in weight-bearing joints, back, thighs and/or calves, difficulty in walking and/or climbing stairs, or running and muscle cramps. Adaptation includes increased parathormone (PTH) and deceased insulin-like growth factor-I (IGF-I) secretion. PTH enhances the tubular reabsorption of Ca and stimulates the kidneys to produce 1, 25-(OH) 2D3 that increases intestinal calcium absorption and dissolves the mineralized collagen matrix in bone, causing osteopenia and osteoporosis to provide enough Ca to prevent hypocalcaemia. Decreased insulin like growth factor-I (IGF-I) delays bone growth to economize calcium consumption. Radiological changes are not uncommon and include osteoporosis/osteopenia affecting long bones as well as vertebrae and ribs, bone cysts, decalcification of the metaphysis of the long bones and pseudo fractures. In severe cases pathological fractures and deformities may occur. Vitamin D treatment of adolescents with VDD differs considerably in different studies and proved to be effective in treating all clinical, biochemical, and radiological manifestations. Different treatment regiments for VDD have been discussed and presented in this mini-review for practical use. Adequate vitamin D replacement after treating VDD, improving calcium intake (milk and dairy products), encouraging adequate exposure

  13. Nutritional assessment and lipid profile in HIV-infected children and adolescents treated with highly active antiretroviral therapy Avaliação nutricional e do perfil lipídico em crianças e adolescentes infectadas pelo HIV tratadas com terapia antirretroviral de alta potência

    Directory of Open Access Journals (Sweden)

    Marina Hjertquist Tremeschin

    2011-06-01

    Full Text Available INTRODUCTION: HIV-infected children and adolescents treated with highly active antiretroviral therapy (HAART regimens that include a protease inhibitor (PI can show significant improvements in clinical outcomes, nutritional status and quality of life. The study aimed to report nutritional and metabolic alterations for pediatric patients continuously exposed to HAART and for healthy controls for up to 1 year. METHODS: Clinical, anthropometric, lipid profile and food intake data were collected prospectively over approximately 12-months for each patient. RESULTS: Fifty-one individuals were studied, of these, 16 were healthy. After 12 months follow-up, HIV-positive individuals remained below the healthy control group parameters. No change was observed concerning food intake. Triglyceride serum levels were higher in patients using protease inhibitor at the onset of the study [PI groups: 114 (43 - 336, and 136 (63 - 271 versus control group: 54.5 (20 - 162; p = 0.003], but after twelve months follow-up, only the group using protease inhibitor for up to two months presented higher values [140 (73 - 273 versus 67.5 (33 - 117; p = 0.004]. HDL-cholesterol was lower in HIV-positive individuals [HIV-positive groups: 36 (27 - 58 and 36 (23 - 43; control 49.5 (34 - 69; p = 0.004]. CONCLUSIONS: HIV-infected children and adolescents treated with highly active antiretroviral therapy showed compromised nutritional parameters compared to a paired healthy control group. Individuals using protease inhibitor presented worse triglyceride serum levels compared to their healthy counterparts.INTRODUÇÃO: Crianças e adolescentes infectadas pelo HIV e tratadas com terapia antirretroviral de alta potência (TAAP, que inclui inibidor de protease (IP podem apresentar significante melhora clínica no estado nutricional e na qualidade de vida. O objetivo é relatar as alterações nutricionais e metabólicas em pacientes pediátricos expostos a TAAP e controles saud

  14. Scleral buckling with a noncontact wide-angle viewing system in the management of retinal detachment with undetected retinal break: a case report

    Directory of Open Access Journals (Sweden)

    Kita M

    2013-03-01

    Full Text Available Mihori Kita, Yukiko Fujii, Naoaki Kawagoe, Sachiyo HamaDepartment of Ophthalmology, National Hospital Organization Kyoto Medical Center, Kyoto, JapanAbstract: A young patient who showed rhegmatogenous retinal detachment with preoperatively undetected retinal break was successfully treated by scleral buckling using a noncontact wide-angle viewing system.Keywords: retinal detachment, retinal breaks, scleral buckling, noncontact wide-angle viewing system

  15. Webcam Delivery of the Camperdown Program for Adolescents Who Stutter: A Phase I Trial

    Science.gov (United States)

    Carey, Brenda; O'Brian, Sue; Onslow, Mark; Packman, Ann; Menzies, Ross

    2012-01-01

    Purpose: This Phase I clinical trial explored the viability of webcam Internet delivery of the Camperdown Program for adolescents who stutter. Method and Procedure: Participants were 3 adolescents ages 13, 15, and 16 years, with moderate-severe stuttering. Each was treated with the Camperdown Program delivered by webcam with no clinic attendance.…

  16. Webcam Delivery of the Camperdown Program for Adolescents Who Stutter: A Phase II Trial

    Science.gov (United States)

    Carey, Brenda; O'Brian, Sue; Lowe, Robyn; Onslow, Mark

    2014-01-01

    Purpose: This Phase II clinical trial examined stuttering adolescents' responsiveness to the Webcam-delivered Camperdown Program. Method: Sixteen adolescents were treated by Webcam with no clinic attendance. Primary outcome was percentage of syllables stuttered (%SS). Secondary outcomes were number of sessions, weeks and hours to maintenance,…

  17. Child and adolescent mental health care in Dutch general practice: time trend analyses.

    NARCIS (Netherlands)

    Zwaanswijk, M.; Dijk, C.E. van; Verheij, R.A.

    2011-01-01

    Background: Because most children and adolescents visit their general practitioner (GP) regularly, general practice is a useful setting in which child and adolescent mental health problems can be identified, treated or referred to specialised care. Measures to strengthen Dutch primary mental health

  18. The effects of physical activity interventions on psychosocial outcomes in adolescents: A meta-analytic review

    NARCIS (Netherlands)

    Spruit, A.; Assink, M.; van Vugt, E.; van der Put, C.; Stams, G.J.

    2016-01-01

    Physical activity interventions are often implemented in the adolescent mental health care practice to prevent or treat psychosocial problems. To date, no systematic review of the effect of these physical activity interventions in adolescents has been conducted. In the current study, four multilevel

  19. Adolescents' Thoughts about Abstinence Curb the Return of Marijuana Use during and after Treatment

    Science.gov (United States)

    King, Kevin M.; Chung, Tammy; Maisto, Stephen A.

    2009-01-01

    Despite evidence showing that readiness to change substance use predicts reductions in substance use among treated adolescents, there is little research on changes in thoughts about abstinence and marijuana use during and after treatment. The current study tested whether time-varying changes in adolescents' motivation to abstain and perceived…

  20. The use and abuse of prescription medication to facilitate or enhance sexual behavior among adolescents.

    Science.gov (United States)

    Apodaca, T R; Moser, N C

    2011-01-01

    Adolescents naturally experience an increased interest in sexual behavior, but they usually lack much experience. Thus, any prescription medication that holds the potential to ease or facilitate sexual matters holds a unique allure. Widespread cultural awareness of medications to treat erectile dysfunction (ED) has combined with a recent trend toward increased adolescent prescription drug abuse to create unique challenges for industry, clinicians, and researchers.

  1. Adult Arrests Records and Court Outcomes of Adolescents with Serious Emotional Disturbance.

    Science.gov (United States)

    Davis, Maryann; Cooper, Deborah K.

    This study used archival data to examine adult charges and court outcomes for 82 individuals who had been treated in public mental health programs as adolescents. Subjects' clinical records from their adolescent day treatment (18 percent), residential (23 percent) or hospital program (58 percent) were reviewed for sociodemographics, clinical…

  2. Surgery for the treatment of obesity in children and adolescents (Review)

    NARCIS (Netherlands)

    Ells, Louisa J.; Mead, Emma; Atkinson, Greg; Corpeleijn, Eva; Roberts, Katharine; Viner, Russell; Baur, Louise; Metzendorf, Maria-Inti; Richter, Bernd

    2015-01-01

    Background Child and adolescent overweight and obesity have increased globally, and are associated with significant short and long term health consequences. Objectives To assess the effects of surgical interventions for treating obesity in childhood and adolescence. Search methods We searched the Co

  3. Participants' Experiences of an Early Cognitive Behavioral Intervention for Adolescents with Symptoms of Depression

    Science.gov (United States)

    Bru, Lene; Solholm, Roar; Idsoe, Thormod

    2013-01-01

    Cognitive-behavioral therapy (CBT) has been documented to be effective in treating depression in adolescence, but there is great variability in the clinical outcome of CBT trials. This may in part be due to variations in the content of, and emphasis on different CBT components. Moreover, little is known about adolescents' subjective experiences of…

  4. Alliance and Outcome in Cognitive-Behavioral Therapy for Adolescent Depression

    Science.gov (United States)

    Shirk, Stephen R.; Gudmundsen, Gretchen; Kaplinski, Heather Crisp; McMakin, Dana L.

    2008-01-01

    This study examined predictive relations between therapeutic alliance and treatment outcomes in manual-guided, cognitive-behavioral therapy for adolescent depression. Fifty-four adolescents met criteria for a depressive disorder and were treated in school-based clinics. Alliance was measured after the third session from both therapist and…

  5. School-Based Cognitive-Behavioral Therapy for Adolescent Depression: A Benchmarking Study

    Science.gov (United States)

    Shirk, Stephen R.; Kaplinski, Heather; Gudmundsen, Gretchen

    2009-01-01

    The current study evaluated cognitive-behavioral therapy (CBT) for adolescent depression delivered in health clinics and counseling centers in four high schools. Outcomes were benchmarked to results from prior efficacy trials. Fifty adolescents diagnosed with depressive disorders were treated by eight doctoral-level psychologists who followed a…

  6. Compliance with the Legislation on Alcohol Serving and Selling and Alcohol Intoxications in Adolescents

    NARCIS (Netherlands)

    Hoof, van Joris J.; Boeynaems, Gerben; Vanderlely, Nicolaas

    2014-01-01

    Purpose: study the relation between compliance to the legal age limits for alcohol sales and alcohol intoxication in adolescents. Methods: from 2007 till 2012 we collected data on adolescents, with a positive BAC, treated in a hospital. Within the Dutch Pediatric Surveillance System (NSCK), pediatr

  7. Pilot Study: Fluvoxamine Treatment for Depression and Anxiety Disorders in Children and Adolescents with Cancer

    Science.gov (United States)

    Gothelf, Doron; Rubinstein, Maly; Shemesh, Eyal; Miller, Orit; Farbstein, Ilana; Klein, Anat; Weizman, Abraham; Apter, Alan; Yaniv, Isaac

    2005-01-01

    Objective: To evaluate the safety, tolerability, and benefit of fluvoxamine for the treatment of major depressive disorder or anxiety disorders in children and adolescents with cancer. Method: The study was conducted from 2001 to 2004 at a pediatric hematology-oncology center. Fifteen children and adolescents with cancer were treated with…

  8. Adolescent childbearing.

    Science.gov (United States)

    Vernon, M

    1991-05-01

    The concern for the consequences of adolescent pregnancy are discussed. Childbirth among unmarried teenagers results in a higher incidence of low birth weight babies, a higher infant mortality and morbidity rate, a higher percentage of childbirth complications, a decreased likelihood of completing school, a higher risk of unemployment and welfare dependency, limited vocational opportunities, larger families, and vulnerability to psychological problems and distress. In 1988, 66% of all births to teens occurred outside of marriage. Out of wedlock live births to teens 14 years rose from 80.8% in 1970 to 92.5% in 1986, and for teens 15-19 years, 29.5% to 60.8%. 70% have a repeat pregnancy within the 1st year following their 1st childbirth. 50% have a 2nd child within 3 years. Most 2nd pregnancies occur in teenagers who are not using effective contractive methods, and the pregnancy is frequently unplanned and unwanted. The factors affecting the rate of 2nd pregnancy are age, race, marital status, education, and economic status. Teenage mothers tend to come from disadvantaged backgrounds, and childbearing compounds the poverty. Aid to families with dependent children 50% of payments were to teen mothers for the birth of their 1st child. Teen fathers are usually low income providers. The public costs are high. Some teen fathers abandon their children after birth, but many are interested in supporting their child. Specific programs to help prepare fathers are needed. Teenage mothers are stressed by child care arrangements, living arrangements, employment, school, relationships with peers, relationships with parents, housework and errands, health, finances, job counseling, community services, and child care information. Parents play an important role in guiding sexual involvement and early childbearing, and need to understand why teens get pregnant and to keep channels of communication open. Teens are influenced by media, peer pressure, lack of self-esteem, unhappiness

  9. Perceived quality of the parental relationship and divorce effects on sexual behaviour in Spanish adolescents.

    Science.gov (United States)

    Orgilés, Mireia; Carratalá, Elena; Espada, José P

    2015-01-01

    Parental divorce has been linked to some risky sexual behaviour in previous studies. Here we examine whether the sexual behaviour of adolescents is related more to the perceived quality of the interparental relationship or to the parents' divorce in a sample from Spain, the country that has experienced the greatest recent increase in marital break-ups in the European Union. Participants were 801 adolescents aged between 14 and 17, who completed questionnaires anonymously. Adolescents who perceive high conflict in their parents' marriages have more sexual activity and engage in more risk practices in some sexual behaviours compared to adolescents with divorced parents and low interparental conflict. When adolescents perceive low conflict, those with divorced parents are more sexually active than adolescents with married parents, but they do not engage in more risk practices. The perceived quality of the parental relationship has a greater negative impact on adolescents than does the type of family structure. The study highlights the need to address the parents' marital relationship in the implementation of prevention programmes of sexual risk behaviours in Spanish adolescents.

  10. DNA Strand Breaks, Neurodegeneration and Aging in the Brain

    Science.gov (United States)

    Katyal, Sachin; McKinnon, Peter J.

    2013-01-01

    Defective responses to DNA single- or double-strand breaks can result in neurological disease, underscoring the critical importance of DNA repair for neural homeostasis. Human DNA repair-deficient syndromes are generally congenital, in which brain pathology reflects the consequences of developmentally incurred DNA damage. Although, it is unclear to what degree DNA strand-break repair defects in mature neural cells contributes to disease pathology. However, DNA single-strand breaks are a relatively common lesion which if not repaired can impact cells via interference with transcription. Thus, this lesion, and probably to a lesser extent DNA double strand breaks, may be particularly relevant to aging in the neural cell population. In this review we will examine the consequences of defective DNA strand break repair towards homeostasis in the brain. Further, we also consider the utility of mouse models as reagents to understand the connection between DNA strand breaks and aging in the brain. PMID:18455751

  11. Symmetry Breaking in MILP Formulations for Unit Commitment Problems

    KAUST Repository

    Lima, Ricardo

    2015-12-11

    This paper addresses the study of symmetry in Unit Commitment (UC) problems solved by Mixed Integer Linear Programming (MILP) formulations, and using Linear Programming based Branch & Bound MILP solvers. We propose three sets of symmetry breaking constraints for UC MILP formulations exhibiting symmetry, and its impact on three UC MILP models are studied. The case studies involve the solution of 24 instances by three widely used models in the literature, with and without symmetry breaking constraints. The results show that problems that could not be solved to optimality within hours can be solved with a relatively small computational burden if the symmetry breaking constraints are assumed. The proposed symmetry breaking constraints are also compared with the symmetry breaking methods included in two MILP solvers, and the symmetry breaking constraints derived in this work have a distinct advantage over the methods in the MILP solvers.

  12. Statistical model on the surface elevation of waves with breaking

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    In the surface wind drift layer with constant momentum flux, two sets of the consistent surface eleva- tion expressions with breaking and occurrence conditions for breaking are deduced from the first in- tegrals of the energy and vortex variations and the kinetic and mathematic breaking criterions, then the expression of the surface elevation with wave breaking is established by using the Heaviside function. On the basis of the form of the sea surface elevation with wave breaking and the understanding of small slope sea waves, a triple composite function of real sea waves is presented including the func- tions for the breaking, weak-nonlinear and basic waves. The expression of the triple composite func- tion and the normal distribution of basic waves are the expected theoretical model for surface elevation statistics.

  13. Eveningness as a risk for behavioral problems in late adolescence.

    Science.gov (United States)

    Merikanto, Ilona; Pesonen, Anu-Katriina; Kuula, Liisa; Lahti, Jari; Heinonen, Kati; Kajantie, Eero; Räikkönen, Katri

    2017-01-01

    Circadian preference toward eveningness has been associated with increased risk for mental health problems both in early adolescence and in adulthood. However, in late adolescence, when circadian rhythm naturally shifts to later, its significance for mental health is not clear. Accordingly, we studied how circadian rhythm estimated both by self-reported chronotype and by actigraph-defined midpoint of sleep was associated with self-reported psychiatric problems based on Youth Self Report (YSR). The study builds on a community cohort born in 1998, Helsinki, Finland. At age 17 years (mean age = 16.9, SD = 0.1 years), 183 adolescents (65.6% of the invited) participated in the study. We used the shortened version of the Horne-Östberg morningness-eveningness Questionnaire to define the chronotype, and actigraphs to define the naturally occur circadian rhythm over a 4 to 17 days' period (mean nights N = 8.3, SD = 1.8). The Achenbach software was used to obtain T-score values for YSR psychiatric problem scales. The analyses were adjusted for important covariates including gender, socioeconomic status, body mass index, pubertal maturation, mother's licorice consumption during pregnancy, and actigraph-defined sleep duration and quality. Eveningness was associated with higher scores in rule-breaking behavior and conduct problems (as assessed either by midpoint of sleep or by self-reported chronotype, p-values adolescents, is also present in late adolescence when circadian rhythms shift toward evening.

  14. Turkish adolescents' loneliness.

    Science.gov (United States)

    Ayhan, Aynur Bütün; Simşek, Sükran; Aral, Neriman; Baran, Gülen

    2012-04-01

    The goal of this study was to characterize loneliness among adolescents with respect to socioeconomic level, sex, and mothers' and fathers' education. General information about the 400 adolescents and their families were obtained. The UCLA Loneliness Scale was administered. Results of a hierarchical multiple regression showed that mothers' educational level explained a slight but statistically significant amount of variance in adolescents' loneliness scores while sex, socioeconomic level and fathers' educational level did not.

  15. Biased discrete symmetry breaking and Fermi balls

    CERN Document Server

    MacPherson, A L; Macpherson, Alick L; Campbell, Bruce A

    1994-01-01

    The spontaneous breaking of an approximate discrete symmetry is considered, with the resulting protodomains of true and false vacuum being separated by domain walls. Given a strong, symmetric Yukawa coupling of the real scalar field to a generic fermion, the domain walls accumulate a gas of fermions, which modify the domain wall dynamics. The splitting of the degeneracy of the ground states results in the false vacuum protodomain structures eventually being fragmented into tiny false vacuum bags with a Fermi gas shell (Fermi balls), that may be cosmologically stable due to the Fermi gas pressure and wall curvature forces, acting on the domain walls. As fermions inhabiting the domain walls do not undergo number density freeze out, stable Fermi balls exist only if a fermion anti-fermion asymmetry occurs. Fermi balls formed with a new Dirac fermion that possesses no standard model gauge charges provide a novel cold dark matter candidate.

  16. Acoustic Emission from Breaking a Bamboo Chopstick

    Science.gov (United States)

    Tsai, Sun-Ting; Wang, Li-Min; Huang, Panpan; Yang, Zhengning; Chang, Chin-De; Hong, Tzay-Ming

    2016-01-01

    The acoustic emission from breaking a bamboo chopstick or a bundle of spaghetti is found to exhibit similar behavior as the famous seismic laws of Gutenberg and Richter, Omori, and Båth. By the use of a force-sensing detector, we establish a positive correlation between the statistics of sound intensity and the magnitude of a tremor. We also manage to derive these laws analytically without invoking the concept of a phase transition, self-organized criticality, or fractal. Our model is deterministic and relies on the existence of a structured cross section, either fibrous or layered. This success at explaining the power-law behavior supports the proposal that geometry is sometimes more important than mechanics.

  17. Supersymmetry Breaking, Gauge Mediation, and the LHC

    Energy Technology Data Exchange (ETDEWEB)

    Shih, David [Rutgers Univ., New Brunswick, NJ (United States)

    2015-04-14

    Gauge mediated SUSY breaking (GMSB) is a promising class of supersymmetric models that automatically satisfies the precision constraints. Prior work of Meade, Seiberg and Shih in 2008 established the full, model-independent parameter space of GMSB, which they called "General Gauge Mediation" (GGM). During the first half of 2010-2015, Shih and his collaborators thoroughly explored the parameter space of GGM and established many well-motivated benchmark models for use by the experimentalists at the LHC. Through their work, the current constraints on GGM from LEP, the Tevatron and the LHC were fully elucidated, together with the possible collider signatures of GMSB at the LHC. This ensured that the full discovery potential for GGM could be completely realized at the LHC.

  18. Symmetry breaking at magnetic surfaces and interfaces

    Energy Technology Data Exchange (ETDEWEB)

    Qiu, Z. Q.

    1998-11-20

    Examples represented of how symmetry breaking enters into consideration of the physical properties of magnetic surfaces and ultrathin films. The role of magnetic anisotropy is discussed to understand: (i) the existence of two-dimensional (2D) magnetic long-ranged order at finite temperature, (ii) magnetization scaling behavior at the Curie transition, (iii) the 2D spin reorientation transition, and (iv) step-induced magnetic behavior. Experimental examples cited include ultrathin magnetic Fe and Co overlayer and wedge structures grown onto single crystal substrates that are either flat or curved to produce vicinal surfaces with a continuous gradient in the step density. Also included is an example of an atomically flat manganite intergrowth that appears as a stacking fault in a bulk single crystal of a naturally layered structure.

  19. Symmetry breaking: The standard model and superstrings

    Energy Technology Data Exchange (ETDEWEB)

    Gaillard, M.K.

    1988-08-31

    The outstanding unresolved issue of the highly successful standard model is the origin of electroweak symmetry breaking and of the mechanism that determines its scale, namely the vacuum expectation value (vev)v that is fixed by experiment at the value v = 4m//sub w//sup 2///g/sup 2/ = (..sqrt..2G/sub F/)/sup /minus/1/ approx. = 1/4 TeV. In this talk I will discuss aspects of two approaches to this problem. One approach is straightforward and down to earth: the search for experimental signatures, as discussed previously by Pierre Darriulat. This approach covers the energy scales accessible to future and present laboratory experiments: roughly (10/sup /minus/9/ /minus/ 10/sup 3/)GeV. The second approach involves theoretical speculations, such as technicolor and supersymmetry, that attempt to explain the TeV scale. 23 refs., 5 figs.

  20. Magnetic rotation and chiral symmetry breaking

    Indian Academy of Sciences (India)

    Ashok Kumar Jain; Amita

    2001-08-01

    The deformed mean field of nuclei exhibits various geometrical and dynamical symmetries which manifest themselves as various types of rotational and decay patterns. Most of the symmetry operations considered so far have been defined for a situation wherein the angular momentum coincides with one of the principal axes and the principal axis cranking may be invoked. New possibilities arise with the observation of rotational features in weakly deformed nuclei and now interpreted as magnetic rotational bands. More than 120 MR bands have now been identified by filtering the existing data. We present a brief overview of these bands. The total angular momentum vector in such bands is tilted away from the principal axes. Such a situation gives rise to several new possibilities including breaking of chiral symmetry as discussed recently by Frauendorf. We present the outcome of such symmetries and their possible experimental verification. Some possible examples of chiral bands are presented.

  1. Gravitino condensation, supersymmetry breaking and inflation

    CERN Document Server

    Houston, N

    2015-01-01

    Motivated by dualistic considerations of the reality of quark condensation in quantum chromodynamics, and the connections of supergravity to the exotic physics of string and M-theory, in this thesis we investigate the dynamical breaking of local supersymmetry via gravitino condensation. We firstly demonstrate non-perturbative gravitino mass generation via this mechanism in flat spacetime, and from this derive the condensate mode wavefunction renormalisation. By then calculating the full canonically normalised one-loop effective potential for the condensate mode about a de Sitter background, we demonstrate that, contrary to claims in the literature, this process may both occur and function in a phenomenologically viable manner. In particular, we find that outside of certain unfortunate gauge choices, the stability of the condensate is intimately tied via gravitational degrees of freedom to the sign of the tree-level cosmological constant. Furthermore, we find that the energy density liberated may provide the n...

  2. Breaking a Dark Degeneracy with Gravitational Waves

    CERN Document Server

    Lombriser, Lucas

    2015-01-01

    We identify a scalar-tensor model embedded in the Horndeski action whose cosmological background and linear scalar fluctuations are degenerate with the concordance cosmology. The model admits a self-accelerated background expansion at late times that is stable against perturbations with a sound speed attributed to the new field that is equal to the speed of light. While degenerate in scalar fluctuations, self acceleration of the model implies a present cosmological tensor mode propagation at 5% less efficient than in general relativity. These discrepancies will be testable with future measurements of gravitational waves emitted by events at cosmological distances. Hence, they can be used to break the dark degeneracy in our current observations between two fundamentally different explanations of cosmic acceleration - a cosmological constant and a scalar-tensor modification of gravity.

  3. Discrete Symmetry Breaking in Fractional Chern Insulators

    Science.gov (United States)

    Kumar, Akshay; Roy, Rahul; Sondhi, S. L.

    2014-03-01

    We study the interplay between quantum hall ordering and spontaneous translational symmetry breaking in a multiple Chern number (C > 1) band at partial filling. We begin with non-interacting fermions in a family of square lattice models with flat C=2 bands and a wide band gap, and add nearest neighbor density-density repulsive interactions. By means of Hartree-Fock theory supplemented by numerical exact diagonalization for a small system at 1/2 filling, we find that the system generically develops charge density wave order with two degenerate ground states. We note that this physics is especially transparent in the limit in which the C=2 band describes two decoupled C=1 bands. We discuss the nature of domain walls in this phase and note the close analogy to the quantum Hall Ising ferromagnet in the multivalley problem. Finally we discuss generalizations to other fillings and higher Chern numbers.

  4. Self-breaking retarded acid emulsion

    Energy Technology Data Exchange (ETDEWEB)

    Scherubel, G.A.

    1979-02-20

    A subterranean formation is acidized with an acid-in-oil emulsion consisting of an aqueous acidizing solution, an oil, an alkyl C/sub 8/ to C/sub 18/ primary fatty amine, and at least one diethanolamide of at least one C/sub 8/ to C/sub 18/ fatty acid. The present invention is an improved acid-in-oil acidizing emulsion, and acidizing method such as an emulsion, the emulsion being of the type containing an effective amount of at least one C/sub 8/ to C/sub 18/ primary amine as a cationic surfactant to increase the normal reaction. The diethanolamine is a nonionic surfactant which causes the emulsion to break as the acidizing capacity of the emulsion becomes substantially depleted, i.e., spent, on the formation. 41 claims.

  5. Dirac Gauginos in Low Scale Supersymmetry Breaking

    CERN Document Server

    Goodsell, Mark D

    2014-01-01

    It has been claimed that Dirac gaugino masses are necessary for realistic models of low-scale supersymmetry breaking, and yet very little attention has been paid to the phenomenology of a light gravitino when gauginos have Dirac masses. We begin to address this deficit by investigating the couplings and phenomenology of the gravitino in the effective Lagrangian approach. We pay particular attention to the phenomenology of the scalar octets, where new decay channels open up. This leads us to propose a new simplified effective scenario including only light gluinos, sgluons and gravitinos, allowing the squarks to be heavy -- with the possible exception of the third generation. Finally, we comment on the application of our results to Fake Split Supersymmetry.

  6. Dirac gauginos in low scale supersymmetry breaking

    Energy Technology Data Exchange (ETDEWEB)

    Goodsell, Mark D., E-mail: mark.goodsell@lpthe.jussieu.fr [Sorbonne Universités, UPMC Univ. Paris 06, UMR 7589, LPTHE, F-75005, Paris (France); CNRS, UMR 7589, LPTHE, F-75005, Paris (France); Tziveloglou, Pantelis, E-mail: pantelis.tziveloglou@vub.ac.be [Theoretische Natuurkunde and IIHE, Vrije Universiteit Brussel, Pleinlaan 2, B-1050 Brussels (Belgium); International Solvay Institutes, Brussels (Belgium)

    2014-12-15

    It has been claimed that Dirac gaugino masses are necessary for realistic models of low-scale supersymmetry breaking, and yet very little attention has been paid to the phenomenology of a light gravitino when gauginos have Dirac masses. We begin to address this deficit by investigating the couplings and phenomenology of the gravitino in the effective Lagrangian approach. We pay particular attention to the phenomenology of the scalar octets, where new decay channels open up. This leads us to propose a new simplified effective scenario including only light gluinos, sgluons and gravitinos, allowing the squarks to be heavy – with the possible exception of the third generation. Finally, we comment on the application of our results to Fake Split Supersymmetry.

  7. Information Content of Spontaneous Symmetry Breaking

    CERN Document Server

    Gleiser, Marcelo

    2012-01-01

    We propose a measure of order in the context of nonequilibrium field theory and argue that this measure, which we call relative configurational entropy (RCE), may be used to quantify the emergence of coherent low-entropy configurations, such as time-dependent or time-independent topological and nontopological spatially-extended structures. As an illustration, we investigate the nonequilibrium dynamics of spontaneous symmetry-breaking in three spatial dimensions. In particular, we focus on a model where a real scalar field, prepared initially in a symmetric thermal state, is quenched to a broken-symmetric state. For a certain range of initial temperatures, spatially-localized, long-lived structures known as oscillons emerge in synchrony and remain until the field reaches equilibrium again. We show that the RCE correlates with the number-density of oscillons, thus offering a quantitative measure of the emergence of nonperturbative spatiotemporal patterns that can be generalized to a variety of physical systems.

  8. Multiscale Simulation of Breaking Wave Impacts

    DEFF Research Database (Denmark)

    Lindberg, Ole

    -distance based adaptivity method and redistributed via a point position filtering method. The incompressible and inviscid ALE-WLS model is applied to the following standard validation test cases: deforming elliptical drop, small amplitude standing waves and the dam break problem. The deforming elliptical drop...... and mass conservation is satisfied through a pressure-corrector type calculation of the pressure. The weighted least squares method (WLS) is combined with approximate Riemann solvers to introduce numerical smoothing of the solution around steep gradients in the velocity and pressure fields. The Poisson...... equation is solved and the pressure boundary conditions are satisfied by a generalized finite pointset method (GFPM); This provides a geometrically flexible and stable solution for the fluid pressure. The numerical approximations of these equations are performed on unstructured point distributions...

  9. Time-symmetry breaking in turbulence

    CERN Document Server

    Jucha, Jennifer; Pumir, Alain; Bodenschatz, Eberhard

    2014-01-01

    In three-dimensional turbulent flows, the flux of energy from large to small scales breaks time symmetry. We show here that this irreversibility can be quantified by following the relative motion of several Lagrangian tracers. We find by analytical calculation, numerical analysis and experimental observation that the existence of the energy flux implies that, at short times, two particles separate temporally slower forwards than backwards, and the difference between forward and backward dispersion grows as $t^3$. We also find the geometric deformation of material volumes, surrogated by four points spanning an initially regular tetrahedron, to show sensitivity to the time-reversal with an effect growing linearly in $t$. We associate this with the structure of the strain rate in the flow.

  10. Higgsless approach to electroweak symmetry breaking

    CERN Document Server

    Grojean, Christophe

    2007-01-01

    Higgsless models are an attempt to achieve a breaking of the electroweak symmetry via boundary conditions at the end-points of a fifth dimension compactified on an interval, as an alternative to the usual Higgs mechanism. There is no physical Higgs scalar in the spectrum and the perturbative unitarity violation scale is delayed via the exchange of massive spin-1 KK resonances. The correct mass spectrum is reproduced in a model in warped space, which inherits a custodial symmetry from a left–right gauge symmetry in the bulk. Phenomenological challenges as well as collider signatures are presented. From the AdS/CFT perspective, this model appears as a weakly coupled dual to walking technicolour models.

  11. Breaking the sound barrier in holography

    Science.gov (United States)

    Hoyos, Carlos; Jokela, Niko; Rodríguez Fernández, David; Vuorinen, Aleksi

    2016-11-01

    It has been conjectured that the speed of sound in holographic models with UV fixed points has an upper bound set by the value of the quantity in conformal field theory. If true, this would set stringent constraints for the presence of strongly coupled quark matter in the cores of physical neutron stars, as the existence of two-solar-mass stars appears to demand a very stiff equation of state. In this article, we present a family of counterexamples to the speed of sound conjecture, consisting of strongly coupled theories at finite density. The theories we consider include N =4 super Yang-Mills at finite R -charge density and nonzero gaugino masses, while the holographic duals are Einstein-Maxwell theories with a minimally coupled scalar in a charged black hole geometry. We show that for a small breaking of conformal invariance, the speed of sound approaches the conformal value from above at large chemical potentials.

  12. Breaking Gaussian incompatibility on continuous variable quantum systems

    Energy Technology Data Exchange (ETDEWEB)

    Heinosaari, Teiko, E-mail: teiko.heinosaari@utu.fi [Turku Centre for Quantum Physics, Department of Physics and Astronomy, University of Turku, FI-20014 Turku (Finland); Kiukas, Jukka, E-mail: jukka.kiukas@aber.ac.uk [Department of Mathematics, Aberystwyth University, Penglais, Aberystwyth, SY23 3BZ (United Kingdom); Schultz, Jussi, E-mail: jussi.schultz@gmail.com [Turku Centre for Quantum Physics, Department of Physics and Astronomy, University of Turku, FI-20014 Turku (Finland); Dipartimento di Matematica, Politecnico di Milano, Piazza Leonardo da Vinci 32, I-20133 Milano (Italy)

    2015-08-15

    We characterise Gaussian quantum channels that are Gaussian incompatibility breaking, that is, transform every set of Gaussian measurements into a set obtainable from a joint Gaussian observable via Gaussian postprocessing. Such channels represent local noise which renders measurements useless for Gaussian EPR-steering, providing the appropriate generalisation of entanglement breaking channels for this scenario. Understanding the structure of Gaussian incompatibility breaking channels contributes to the resource theory of noisy continuous variable quantum information protocols.

  13. Three-Dimensional Simulations of Deep-Water Breaking Waves

    CERN Document Server

    Brucker, Kyle A; Dommermuth, Douglas G; Adams, Paul

    2014-01-01

    The formulation of a canonical deep-water breaking wave problem is introduced, and the results of a set of three-dimensional numerical simulations for deep-water breaking waves are presented. In this paper fully nonlinear progressive waves are generated by applying a normal stress to the free surface. Precise control of the forcing allows for a systematic study of four types of deep-water breaking waves, characterized herein as weak plunging, plunging, strong plunging, and very strong plunging.

  14. DNA Strand Breaks, Neurodegeneration and Aging in the Brain

    OpenAIRE

    Katyal, Sachin; McKinnon, Peter J

    2008-01-01

    Defective responses to DNA single- or double-strand breaks can result in neurological disease, underscoring the critical importance of DNA repair for neural homeostasis. Human DNA repair-deficient syndromes are generally congenital, in which brain pathology reflects the consequences of developmentally incurred DNA damage. Although, it is unclear to what degree DNA strand-break repair defects in mature neural cells contributes to disease pathology. However, DNA single-strand breaks are a relat...

  15. Review of Rotational Symmetry Breaking in Baby Skyrme Models

    CERN Document Server

    Karliner, Marek

    2009-01-01

    We discuss one of the most interesting phenomena exhibited by baby skyrmions -- breaking of rotational symmetry. The topics we will deal with here include the appearance of rotational symmetry breaking in the static solutions of baby Skyrme models, both in flat as well as in curved spaces, the zero-temperature crystalline structure of baby skyrmions, and finally, the appearance of spontaneous breaking of rotational symmetry in rotating baby skyrmions.

  16. Soft breaking of BRST symmetry and gauge dependence

    CERN Document Server

    Lavrov, P M; Reshetnyak, A A

    2012-01-01

    We continue investigation of soft breaking of BRST symmetry in the Batalin-Vilkovisky (BV) formalism beyond regularizations like dimensional ones used in our previous paper. We generalize a definition of soft breaking of BRST symmetry valid for general gauge theories and arbitrary gauge fixing. The gauge dependence of generating functionals of Green's functions is investigated. It is proved that such introduction of a soft breaking of BRST symmetry into gauge theories leads to inconsistency of the conventional BV formalism.

  17. Dynamical Breaking of Generalized Yang-Mills Theory

    Institute of Scientific and Technical Information of China (English)

    WANGDian-Fu; SONGHe-Shan

    2004-01-01

    The dynamical breaking of a generalized Yang-Mills theory is discussed. It is shown, in terms of the Nambu Jona-Lasinio mechanism, that the gauge symmetry breaking can be realized dynamically in the generalized Yang-Mills theory. The combination of the generalized Yang-Mills theory and the NJL mechanism provides a way to overcome the difficulties related to the Higgs field and the Higgs mechanism in the usual spontaneous symmetry breaking theory.

  18. Dynamical Breaking of Generalized Yang-Mills Theory

    Institute of Scientific and Technical Information of China (English)

    WANG Dian-Fu; SONG He-Shah

    2004-01-01

    The dynamical breaking of a generalized Yang-Mills theory is discussed. It is shown, in terms of the Nambu-Jona-Lasinio mechanism, that the gauge symmetry breaking can be realized dynamically in the generalized Yang-Mills theory. The combination of the generalized Yang-Mills theory and the NJL mechanism provides a way to overcome the difficulties related to the Higgs field and the Higgs mechanism in the usual spontaneous symmetry breaking theory.

  19. Socially-induced morphine pseudo-sensitization in adolescent mice

    OpenAIRE

    Hodgson, Stephen R.; Hofford, Rebecca S.; Roberts, Kris W.; Wellman, Paul J.; Eitan, Shoshana

    2010-01-01

    Given that social influences are among the strongest predictors of adolescents’ drug use, this study examined the effect of social interaction on morphine-induced hyper-locomotion in both adolescent and adult mice. Three experimental groups of adolescent and adult male mice were examined: 1) morphine-treated mice (twice daily, 10–40 mg/kg, s.c.), 2) saline-injected mice housed together with the morphine-treated mice (‘saline cage-mates’), and 3) saline-injected mice housed physically and visu...

  20. Adolescent pregnancy and contraception.

    Science.gov (United States)

    Dalby, Jessica; Hayon, Ronni; Carlson, Jensena

    2014-09-01

    7% of US teen women became pregnant in 2008, totaling 750,000 pregnancies nationwide. For women ages 15 to 19, 82% of pregnancies are unintended. Adolescents have a disproportionate risk of medical complications in pregnancy. Furthermore, adolescent parents and their infants both tend to suffer poor psychosocial outcomes. Preventing unintended and adolescent pregnancies are key public health objectives for Healthy People 2020. Screening for sexual activity and pregnancy risk should be a routine part of all adolescent visits. Proven reductions in unintended pregnancy in teens are attained by providing access to contraception at no cost and promoting the most-effective methods.

  1. Nutrition in the adolescent.

    Science.gov (United States)

    Wahl, R

    1999-02-01

    This article reviews the nutritional requirements of puberty and the clinical assessment of nutritional status, and discusses the nutritional risks imposed by vegetarian diets, pregnancy, and athletic involvement. Energy (calories) and protein are essential in pubertal development. Adolescent females require approximately 2200 calories/day, whereas male adolescents require 2500-3000 calories/day. Additional intake requirements include fat, calcium, iron, zinc, vitamins, and fiber. The clinical assessment of nutritional status begins with obtaining a good diet history of the patient and this could be offered by the body mass index. Nutritional deficiencies and poor eating habits established during adolescence can have long-term consequences, including delayed sexual maturation, loss of final adult height, osteoporosis, hyperlipidemia, and obesity. As for vegetarian adolescents, nutritional risks include lack of iodine, vitamin B12, vitamin D, and some essential fatty acids. In addition, substances in some grains reduce gut absorption, thus increasing mineral deficiencies. Pregnancy may also be a risk factor for poor nutrition during adolescence. A pregnant adolescent has different nutritional needs because she is still growing. Among adolescent athletes many are turning to nutritional supplements in an attempt to improve athletic performance. A balanced, varied diet provides adequate calories and nutrition to meet the needs of most adolescents. They also have greater water needs than do adult athletes. Details on adolescent health concerns are further discussed in this article.

  2. A Boussinesq Equation-Based Model for Nearshore Wave Breaking

    Institute of Scientific and Technical Information of China (English)

    余建星; 张伟; 王广东; 杨树清

    2004-01-01

    Based on the wave breaking model by Li and Wang (1999), this work is to apply Dally' s analytical solution to the wave-height decay irstead of the empirical and semi-empirical hypotheses of wave-height distribution within the wave breaking zone. This enhances the applicability of the model. Computational results of shoaling, location of wave breaking, wave-height decay after wave breaking, set-down and set-up for incident regular waves are shown to have good agreement with experimental and field data.

  3. Can spontaneous symmetry breaking occur in potential with one minimum?

    CERN Document Server

    Acus, A

    2000-01-01

    Spontaneous symmetry breaking occurs when the symmetry that a physical system possesses, is not preserved for the ground state of the system. Although the procedure of symmetry breaking is quite clear from the mathematical point of view, the physical interpretation of the phenomenon is worth to be better understood. In this note we present a simple and instructive example of the symmetry breaking in a mechanical system. It demonstrates that the spontaneous symmetry breaking can occur for the spatially extended solutions in a potential characterised by a single minimum.

  4. Wilson flux breaking and coset space dimensional reduction

    Energy Technology Data Exchange (ETDEWEB)

    Zoupanos, G.

    1988-02-11

    Higher dimensional gauge theories lead, after dimensional reduction on coset spaces, to four-dimensional gauge theories usually with the natural emergence of a Higgs sector which is completely determined. However, the Higgs fields never appear in the adjoint representation which in many GUTs could lead to a successful spontaneous symmetry breaking towards the low energy gauge group. As an alternative we suggest that the breaking of the four-dimensional GUTs obtained from CSDR could be provided by the Wilson flux breaking and we discuss some semirealistic examples. We also speculate on the possibility that the breaking of the electroweak sector has dynamical origin.

  5. Simulation of dike-break processes in the Yellow River

    Institute of Scientific and Technical Information of China (English)

    LIANG; Lin(梁林); NI; Jinren(倪晋仁); A.G.L.; Borthwick; B.D.; Rogers

    2002-01-01

    Although dike-break and dam-break processes have similar unsteady and discontinuous hydrodynamic characteristics, there are significant differences. In general, dam-break simulations focus on the flood discharge, whereas dike-break simulations are required to provide detailed information on the hydraulic and breach evolution processes, such as pit-scour and breach-expansion. In order to overcome the difficulties inherent in applying existing dam-break models to dike-breaks, this paper presents an integrated model that combines the shallow water, sediment transport, riverbed deformation and breach-expansion equations. A Godunov-type finite volume method is used for the flow simulation, based on a fixed quadtree grid system. The hydrodynamic aspects of the model are validated for an idealized rectangular dam break. A representative reach in the Yellow River is selected at a location where there is a significant risk of a dike-break, and full-scale topographic and hydrologic data are available. Typical dike-break processes are successfully simulated, with predicted hydraulic characteristics and terrain changes qualitatively in agreement with laboratory data. The modeling study is of practical importance for implementation of engineering countermeasures in the Yellow River, such as breach blocking and head wrapping.

  6. Counseling sexually active teenagers treated with potential human teratogens.

    Science.gov (United States)

    Shilalukey, K; Kaufman, M; Bradley, S; Francombe, W H; Amankwah, K; Goldberg, E; Shear, N; Olivieri, N F; Koren, G

    1997-09-01

    Adolescents with hemoglobinopathies need daily chelation therapy with drugs which are known or suspected to be teratogenic. The prevention of fetal exposure to such drugs is therefore a major task for health professionals caring for these patients. We describe a pilot program aiming to prevent pregnancy among sexually active adolescents treated with iron chelators in Toronto. Most of them had normal response to GnRH, suggesting endocrinologic fertility, and unlike the literature concerning their healthy peers, all sexually active patients in this study reported use of at least one form of contraception.

  7. Factors associated with the over-treatment and under-treatment of gonorrhea and chlamydia in adolescents presenting to a public hospital emergency department

    Directory of Open Access Journals (Sweden)

    Mutimbwa Anaene

    2016-12-01

    Conclusion: Adolescents and young adults screened for STIs have a high prevalence of GC/CT. A significant proportion of these patients end up over-treated and an even higher proportion are under-treated.

  8. Adolescent physical activity and health: a systematic review.

    Science.gov (United States)

    Hallal, Pedro C; Victora, Cesar G; Azevedo, Mario R; Wells, Jonathan C K

    2006-01-01

    Physical activity in adolescence may contribute to the development of healthy adult lifestyles, helping reduce chronic disease incidence. However, definition of the optimal amount of physical activity in adolescence requires addressing a number of scientific challenges. This article reviews the evidence on short- and long-term health effects of adolescent physical activity. Systematic reviews of the literature were undertaken using a reference period between 2000 and 2004, based primarily on the MEDLINE/PubMed database. Relevant studies were identified by examination of titles, abstracts and full papers, according to inclusion criteria defined a priori. A conceptual framework is proposed to outline how adolescent physical activity may contribute to adult health, including the following pathways: (i) pathway A--tracking of physical activity from adolescence to adulthood; (ii) pathway B--direct influence of adolescent physical activity on adult morbidity; (iii) pathway C--role of physical activity in treating adolescent morbidity; and (iv) pathway D - short-term benefits of physical activity in adolescence on health. The literature reviews showed consistent evidence supporting pathway 'A', although the magnitude of the association appears to be moderate. Thus, there is an indirect effect on all health benefits resulting from adult physical activity. Regarding pathway 'B', adolescent physical activity seems to provide long-term benefits on bone health, breast cancer and sedentary behaviours. In terms of pathway 'C', water physical activities in adolescence are effective in the treatment of asthma, and exercise is recommended in the treatment of cystic fibrosis. Self-esteem is also positively affected by adolescent physical activity. Regarding pathway 'D', adolescent physical activity provides short-term benefits; the strongest evidence refers to bone and mental health. Appreciation of different mechanisms through which adolescent physical activity may influence adult

  9. Cognitive Behavioral Treatment for Posttraumatic Stress Disorder in Children and Adolescents

    OpenAIRE

    Dorsey, Shannon; Briggs, Ernestine C.; Woods, Briana A.

    2011-01-01

    A number of Cognitive Behavioral Therapy (CBT) approaches are available for treating child and adolescent posttraumatic stress disorder (PTSD). Similar to other CBT treatments, particularly those for anxiety disorders, these treatments all include common elements (e.g., psychoeducation, relaxation and affective modulation skills, exposure). The goals of this review are to: 1) delineate common elements in CBT approaches for treating child and adolescent PTSD; 2) provide a detailed review of tw...

  10. Supersymmetry Breaking in Disordered Systems and Relation to Functional Renormalization and Replica-Symmetry Breaking

    OpenAIRE

    Wiese, Kay Joerg

    2004-01-01

    In this article, we study an elastic manifold in quenched disorder in the limit of zero temperature. Naively it is equivalent to a free theory with elasticity in Fourier-space proportional to k^4 instead of k^2, i.e. a model without disorder in two space-dimensions less. This phenomenon, called dimensional reduction, is most elegantly obtained using supersymmetry. However, scaling arguments suggest, and functional renormalization shows that dimensional reduction breaks down beyond the Larkin ...

  11. Baixa renda como fator de proteção contra asma em crianças e adolescentes usuários do Sistema Único de Saúde Low income as a protective factor against asthma in children and adolescents treated via the Brazilian Unified Health System

    Directory of Open Access Journals (Sweden)

    Murilo Carlos Amorim de Britto

    2008-05-01

    -off points related to the national minimum wage (R$350.00: 50% of minimum wage = satisfactory income (23.7% of the sample. There was no association between poverty and development of asthma. CONCLUSIONS: Poverty is not protective against asthma in children and adolescents treated via the Brazilian Unified Health System, as we might suppose based on the hygiene hypothesis. However, cohort studies are needed in order to confirm these findings.

  12. A Microscopic View of Oil Slick Break-Up and Emulsion Formation in Breaking Waves

    Science.gov (United States)

    Law, J.; Shahrokhi, H.; Shaw, J. M.

    1996-11-01

    The hydrodynamic behaviour of oil spills in breaking waves determines the appropriateness and effectiveness of remedial measures during clean-up operations. Oil slicks either disperse as fine drops or form water in oil emulsions when exposed to breaking waves. However, there is little agreement with respect to the controlling variables or mechanisms for emulsification or dispersion and predictions are unreliable. For example, predicted energy dissipation rates in breaking waves are too low to account for the drop sizes encountered experimentally[1]. In this paper, we assess the impact of hydrodynamics and physical properties on the formation of dispersions or emulsions. The maximum stable drop size for dispersions arising from oil slicks and water in oil emulsions are shown to be controlled by Raleigh-Taylor instability or the prevalent local shear stress. Data from four experimental studies[2-5], with a broad range of physical properties were fitted quantitatively. As high shear events are intermittent, stable water in oil emulsions can be formed by dispersion inversion near the water air interface or by water entrained by gas bubbles passing through oil slicks. 1) Li & Garrett, 19th AMOP, Calgary AB, 1, 185-198 (1996). 2) Lin et al., Report CG-D-54-78, U.S. Coast Guard, Washington D.C. (1978). 3) Buist, MASc Thesis, University of Toronto (1979). 4) Wallace et al., 9th AMOP, Edmonton AB, 2, 421-429, June 10-12 (1986). 5) Ross Environmental Research Ltd., Ottawa ON, Report EE-96, (1987).

  13. Skills Associated with Line Breaks in Elite Rugby Union

    Directory of Open Access Journals (Sweden)

    Steve den Hollander, James Brown, Michael Lambert, Paul Treu, Sharief Hendricks

    2016-09-01

    Full Text Available The ability of the attacking team to break through the defensive line is a key indicator of success as it creates opportunities to score tries. The aim of this study was to analyse line breaks and identify the associated skills and playing characteristics. The 2013 Super Rugby season (125 games was analysed, in which 362 line breaks were identified and coded using variables that assessed team patterns and non-contact attacking skills in the phases preceding the line break. There was an average of 3 line breaks per game, with 39% of line breaks resulting in a try. Line breaks occurred when the ball-carrier was running fast [61%, x2(4 = 25.784, p = 0.000, Cramer’s v = 0.1922, weak]. At a moderate distance, short lateral passes (19% and skip passes (15% attributed to the highest percentage of line breaks [x2(26 = 50.899, p = 0.036, Cramer’s v = 0.2484, moderate]. Faster defensive line speeds resulted in more line breaks [x2(12 = 61.703, p < 0.001, Cramer’s v = 0.3026, moderate]. Line breaks are associated with overall team success and try scoring opportunities. Awareness of the defenders line speed and depth, fast running speed when receiving the ball and quick passing between attackers to the outside backs creates line break opportunities. During training, coaches should emphasise the movement speed of the ball between attackers and manipulate the speed and distance of the defenders.

  14. Do Adolescents Prefer Electronic Books to Paper Books?

    Directory of Open Access Journals (Sweden)

    Margaret K. Merga

    2015-11-01

    Full Text Available While electronic books offer a range of benefits and may be supposed to be more appealing to young people than paper books, this assumption is often treated as fact by educational researchers. Understanding adolescents’ true current preferences is essential, as incorrect assumptions can lead to decisions which restrict adolescent access to their preferred book mode. The belief that adolescents prefer electronic books to paper books has already led to some school libraries being expunged of paper books. As adolescents show a higher level of aliteracy than younger children, and regular reading offers a broad range of benefits for young people, it is imperative that school’s decisions around providing access to books are responsive to adolescent students’ genuine preferences. This paper analyses the current and relevant academic research around adolescent preferences for book modes, finding that, at present, the contention that adolescents prefer electronic books is not supported by the available research. In addition, there are a number of issues identified that make analyzing the findings in this area problematic. Future studies in this area are needed before an adolescent preference for electronic books can be unequivocally substantiated.

  15. Pathological Internet Use and Risk-Behaviors among European Adolescents

    Directory of Open Access Journals (Sweden)

    Tony Durkee

    2016-03-01

    Full Text Available Risk-behaviors are a major contributor to the leading causes of morbidity among adolescents and young people; however, their association with pathological Internet use (PIU is relatively unexplored, particularly within the European context. The main objective of this study is to investigate the association between risk-behaviors and PIU in European adolescents. This cross-sectional study was conducted within the framework of the FP7 European Union project: Saving and Empowering Young Lives in Europe (SEYLE. Data on adolescents were collected from randomized schools within study sites across eleven European countries. PIU was measured using Young’s Diagnostic Questionnaire (YDQ. Risk-behaviors were assessed using questions procured from the Global School-Based Student Health Survey (GSHS. A total of 11,931 adolescents were included in the analyses: 43.4% male and 56.6% female (M/F: 5179/6752, with a mean age of 14.89 ± 0.87 years. Adolescents reporting poor sleeping habits and risk-taking actions showed the strongest associations with PIU, followed by tobacco use, poor nutrition and physical inactivity. Among adolescents in the PIU group, 89.9% were characterized as having multiple risk-behaviors. The significant association observed between PIU and risk-behaviors, combined with a high rate of co-occurrence, underlines the importance of considering PIU when screening, treating or preventing high-risk behaviors among adolescents.

  16. The relationship between Asperger's syndrome and schizophrenia in adolescence.

    Science.gov (United States)

    Waris, Petra; Lindberg, Nina; Kettunen, Kirsi; Tani, Pekka

    2013-04-01

    Asperger's syndrome (AS), a pervasive developmental disorder (PDD), has nowadays been widely advocated in media. Therefore, psychiatrists treating adolescents frequently meet patients as well as their families reporting of symptoms resembling those of Asperger's syndrome. It is known that symptoms of Asperger's syndrome have some overlap with those of schizophrenia, but less is known about comorbidity between these two syndromes. We describe a sample of 18 adolescents with early onset schizophrenia. Diagnosis of schizophrenia was based on assessment with Kiddie Schedule for Affective Disorders and Schizophrenia. The diagnostic interview for Social and Communication Disorders version 11 was used to assess autism spectrum disorders. Ten adolescents fulfilled symptom criteria of Asperger's syndrome after the onset of schizophrenia, while only two persons had Asperger's syndrome before the onset of schizophrenia, a prerequisite for diagnosis. 44% of the adolescents fulfilled the diagnosis of some PDD in childhood. Most of them were, however, unrecognized before the onset of schizophrenia. On the other hand, all 18 patients had one or more symptoms of PDDS in adolescence. Adolescents with schizophrenia have often symptoms consistent with AS, although only few of them have fulfilled the diagnostic criteria in their childhood, a prerequisite for the diagnosis of AS. There is a risk for misdiagnosis of adolescents with autistic symptoms if detailed longitudinal anamnesis is not obtained.

  17. Pathological Internet Use and Risk-Behaviors among European Adolescents.

    Science.gov (United States)

    Durkee, Tony; Carli, Vladimir; Floderus, Birgitta; Wasserman, Camilla; Sarchiapone, Marco; Apter, Alan; Balazs, Judit A; Bobes, Julio; Brunner, Romuald; Corcoran, Paul; Cosman, Doina; Haring, Christian; Hoven, Christina W; Kaess, Michael; Kahn, Jean-Pierre; Nemes, Bogdan; Postuvan, Vita; Saiz, Pilar A; Värnik, Peeter; Wasserman, Danuta

    2016-03-08

    Risk-behaviors are a major contributor to the leading causes of morbidity among adolescents and young people; however, their association with pathological Internet use (PIU) is relatively unexplored, particularly within the European context. The main objective of this study is to investigate the association between risk-behaviors and PIU in European adolescents. This cross-sectional study was conducted within the framework of the FP7 European Union project: Saving and Empowering Young Lives in Europe (SEYLE). Data on adolescents were collected from randomized schools within study sites across eleven European countries. PIU was measured using Young's Diagnostic Questionnaire (YDQ). Risk-behaviors were assessed using questions procured from the Global School-Based Student Health Survey (GSHS). A total of 11,931 adolescents were included in the analyses: 43.4% male and 56.6% female (M/F: 5179/6752), with a mean age of 14.89 ± 0.87 years. Adolescents reporting poor sleeping habits and risk-taking actions showed the strongest associations with PIU, followed by tobacco use, poor nutrition and physical inactivity. Among adolescents in the PIU group, 89.9% were characterized as having multiple risk-behaviors. The significant association observed between PIU and risk-behaviors, combined with a high rate of co-occurrence, underlines the importance of considering PIU when screening, treating or preventing high-risk behaviors among adolescents.

  18. Friday on My Mind: The Relation of Partying with Antisocial Behavior of Early Adolescents. The TRAILS Study

    Science.gov (United States)

    Veenstra, Rene; Huitsing, Gijs; Dijkstra, Jan Kornelis; Lindenberg, Siegwart

    2010-01-01

    The relation between partying and antisocial behavior was investigated using a sample of Dutch early adolescents (T2: N = 1,076; M age = 13.52). Antisocial behavior was divided into rule-breaking and aggressive behavior. Using a goal-framing approach, it was argued that the relation of partying to antisocial behavior depends on the way the need to…

  19. Friday on My Mind : The Relation of Partying With Antisocial Behavior of Early Adolescents. The TRAILS Study

    NARCIS (Netherlands)

    Veenstra, Rene; Huitsing, Gijs; Dijkstra, Jan; Lindenberg, Siegwart

    2010-01-01

    The relation between partying and antisocial behavior was investigated using a sample of Dutch early adolescents (T2: N=1,076; M age=13.52). Antisocial behavior was divided into rule-breaking and aggressive behavior. Using a goal-framing approach, it was argued that the relation of partying to antis

  20. Laparoscopic cryoablation of angiomyolipomas in adolescents and young adults

    DEFF Research Database (Denmark)

    Trelborg, Karina; Nielsen, Tommy Kjærgaard; Østraat, Ernst Øyvind;

    2016-01-01

    described in adults, whereas experiences with adolescents and young adults are limited. We present here for the first time a series of renal AMLs within adolescents and young adults treated with laparoscopic assisted cryoablation (LCA). OBJECTIVE: The aim was to evaluate whether LCA of AMLs in adolescents...... and young adults is a safe and feasible treatment modality. STUDY DESIGN: From October 2009 to September 2013 a total of five patients at our institution were diagnosed with AMLs requiring treatment. Four patients had TS and one had AML of sporadic origin, all five patients underwent LCA. Data were......-sparing approach in adolescents and young adults. The low perioperative complication rate and promising effect on outcome might allow treatment of subclinical AMLs in order to minimize the risk of potentially life-threatening complications and preserve renal function....

  1. Gender and Adolescent Development

    Science.gov (United States)

    Perry, David G.; Pauletti, Rachel E.

    2011-01-01

    This article summarizes and critiques recent trends in research and theory on the role of gender in adolescent development. First, gender differences in key areas of adolescent functioning are reviewed. Second, research on 3 constructs that are especially relevant to the investigation of within-gender individual differences in gender…

  2. Adolescence Education Newsletter, 2001.

    Science.gov (United States)

    Villanueva, Carmelita L., Ed.; Espada-Carlos, Lichelle Dara, Ed.

    2001-01-01

    This document comprises the two 2001 issues of a UNESCO newsletter addressing topics related to adolescent well-being in the Asia-Pacific region, particularly reproductive and sexual health. Each issue contains news from the region on various initiatives related to adolescent health and education, as well as Web links and publications on the…

  3. Adolescence Education Newsletter, 1999.

    Science.gov (United States)

    Villanueva, Carmelita L., Ed.; Padilla, Teresita M., Ed.

    1999-01-01

    This document comprises the two 1999 issues of a UNESCO newsletter addressing topics related to adolescent well-being in the Asia-Pacific region, particularly reproductive and sexual health. Each issue contains news from the region on various initiatives related to adolescent heath and education, as well as Web links and publications on the…

  4. Adolescence Education Newsletter, 1998.

    Science.gov (United States)

    Villanueva, Carmelita L., Ed.; Padilla, Teresita M., Ed.

    1998-01-01

    This document comprises two issues of a new UNESCO newsletter addressing topics related to adolescent well-being in the Asia-Pacific region, particularly reproductive and sexual health. Both issues contain news from the region on various initiatives related to adolescent health and education, as well as Web links and publications on the subject.…

  5. Adolescence Education Newsletter, 2000.

    Science.gov (United States)

    Villanueva, Carmelita L., Ed.; Padilla, Teresita M., Ed.

    2000-01-01

    This document comprises the two 2000 issues of a UNESCO newsletter addressing topics related to adolescent well-being in the Asia-Pacific region, particularly reproductive and sexual health. Each issue contains news from the region on various initiatives related to adolescent health and education, as well as Web links and publications on the…

  6. Adolescence Education Newsletter, 2002.

    Science.gov (United States)

    Villanueva, Carmelita L., Ed.; Espada-Carlos, Lichelle Dara, Ed.

    2002-01-01

    This document consists of the two 2002 issues of a UNESCO newsletter addressing topics related to adolescent well-being in the Asia-Pacific region, particularly reproductive and sexual health. Each issue includes news from the region on various initiatives related to adolescent health and education, as well as Web links and publications on the…

  7. Early Adolescent Ego Development.

    Science.gov (United States)

    James, Michael A.

    1980-01-01

    Presented are the theoretical characteristics of social identity in early adolescence (ages 10 to 15). It is suggested that no longer is identity thought to begin with adolescence, but may have its beginnings in the preteen years. The article draws heavily on Eriksonian concepts. (Editor/KC)

  8. Adolescent Rebellion and Politics.

    Science.gov (United States)

    Meeus, Wim

    1988-01-01

    Examination of 352 Dutch secondary school students reveals that adolescents with high-level education who endorse adolescent rebellion have a more distinctly left-wing profile--in both their political party preferences and their political views--than those with low-level education, who more often ratified political intolerance. (BJV)

  9. Adolescent Development Reconsidered.

    Science.gov (United States)

    Gilligan, Carol

    1987-01-01

    Emphasizes necessity of reconsideration of adolescent development, for these reasons: the view of childhood has changed; females have not been systematically studied; theories of cognitive development favor mathematical and scientific thinking over the humanities; and because the psychology of adolescence is anchored in separation and independence…

  10. Adolescent Literacy. Focus On

    Science.gov (United States)

    Molineaux, Rebecca

    2009-01-01

    Evidence suggests that there is a crisis in adolescent literacy. Part of the problem is that students often receive little literacy instruction after elementary school. This "Focus On" examines the literacy instruction that adolescents need to be successful as they move on to more challenging texts in middle and high school. In addition, this…

  11. The Adolescent Brain

    Science.gov (United States)

    Casey, B. J.; Getz, Sarah; Galvan, Adriana

    2008-01-01

    Adolescence is a developmental period characterized by suboptimal decisions and actions that give rise to an increased incidence of unintentional injuries and violence, alcohol and drug abuse, unintended pregnancy and sexually transmitted diseases. Traditional neurobiological and cognitive explanations for adolescent behavior have failed to…

  12. Adolescent Steroid Use.

    Science.gov (United States)

    Office of Inspector General (DHHS), Washington, DC.

    The study focused on non-medical steroid use by adolescents according to data obtained from the National Institute on Drug Abuse, professional literature, 30 key informants knowledgeable in steroid issues, and 72 current or former steroid users. The findings indicated: (1) over 250,000 adolescents, primarily males, used or have used steroids, and…

  13. Diagnosing ADHD in Adolescence

    Science.gov (United States)

    Sibley, Margaret H.; Pelham, William E., Jr.; Molina, Brooke S. G.; Gnagy, Elizabeth M.; Waschbusch, Daniel A.; Garefino, Allison C.; Kuriyan, Aparajita B.; Babinski, Dara E.; Karch, Kathryn M.

    2012-01-01

    Objective: This study examines adolescent-specific practical problems associated with current practice parameters for diagnosing attention-deficit/hyperactivity disorder (ADHD) to inform recommendations for the diagnosis of ADHD in adolescents. Specifically, issues surrounding the use of self- versus informant ratings, diagnostic threshold, and…

  14. A systematic review of community-based parenting interventions for adolescents with challenging behaviours.

    Science.gov (United States)

    Medlow, Sharon; Klineberg, Emily; Jarrett, Carmen; Steinbeck, Katharine

    2016-10-01

    Parenting skills training is an established means of treating challenging behaviours among young children, but there has been limited research on its efficacy when used to treat challenging adolescent behaviour. The aim of this systematic review was to evaluate the efficacy and effectiveness of community-based parenting interventions designed for families with adolescents, as judged in terms of increased knowledge and skills among parents, improvements in adolescent behaviour, and program feasibility within community settings. Results indicated that intervention group parents typically made greater gains than did control group parents on measures of good parenting, with positive flow-on effects to some aspects of challenging adolescent behaviours. Limited evidence suggests that group and individual intervention formats may be equally effective and that there is no advantage to the participation of the target adolescent in the intervention.

  15. The Adolescent Behavioral Activation Program: Adapting Behavioral Activation as a Treatment for Depression in Adolescence.

    Science.gov (United States)

    McCauley, Elizabeth; Gudmundsen, Gretchen; Schloredt, Kelly; Martell, Christopher; Rhew, Isaac; Hubley, Samuel; Dimidjian, Sona

    2016-01-01

    This study aimed to examine implementation feasibility and initial treatment outcomes of a behavioral activation (BA) based treatment for adolescent depression, the Adolescent Behavioral Activation Program (A-BAP). A randomized, controlled trial was conducted with 60 clinically referred adolescents with a depressive disorder who were randomized to receive either 14 sessions of A-BAP or uncontrolled evidenced-based practice for depression. The urban sample was 64% female, predominantly Non-Hispanic White (67%), and had an average age of 14.9 years. Measures of depression, global functioning, activation, and avoidance were obtained through clinical interviews and/or through parent and adolescent self-report at preintervention and end of intervention. Intent-to-treat linear mixed effects modeling and logistic regression analysis revealed that both conditions produced statistically significant improvement from pretreatment to end of treatment in depression, global functioning, and activation and avoidance. There were no significant differences across treatment conditions. These findings provide the first step in establishing the efficacy of BA as a treatment for adolescent depression and support the need for ongoing research on BA as a way to enhance the strategies available for treatment of depression in this population.

  16. Parents' and Adolescents' Preferences for Intensified or Reduced Treatment in Randomized Lymphoblastic Leukemia Trials

    DEFF Research Database (Denmark)

    Tulstrup, Morten; Larsen, Hanne Baekgaard; Castor, Anders;

    2016-01-01

    .01). Younger children participated more frequently in only 6MP than in only ASP (14% vs. 5%), and adolescents vice versa (2% vs. 17%; P = 0.001). CONCLUSIONS: Parents' and adolescents' divergent inclinations toward intensified or reduced therapy emphasize the necessity of actively involving adolescents......BACKGROUND: When offered participation in clinical trials, families of children with cancer face a delicate balance between cure and toxicity. Since parents and children may perceive this balance differently, this paper explores whether adolescent patients have different enrollment patterns...... prospectively registered by the treating physicians. RESULTS: Parents of young children favored treatment intensifications (Dx/VCR: 12% refusal; 6MP: 14%; ASP: 21%), whereas parents of adolescents favored treatment reductions (Dx/VCR: 52% refusal; 6MP: 30%; ASP: 8%). Adolescents were more likely to refuse...

  17. Psychotherapeutic approaches to non-suicidal self-injury in adolescents

    Directory of Open Access Journals (Sweden)

    Washburn Jason J

    2012-03-01

    Full Text Available Abstract Non-suicidal self-injury (NSSI among adolescents is gaining increasing attention in both clinical and scientific arenas. The lifetime prevalence of NSSI is estimated to vary between 7.5% to 8% for preadolescents, increasing to between 12% and 23% for adolescents. Despite the prevalence and the increasing interest in NSSI, few psychotherapeutic treatments have been designed specifically for NSSI, and no treatments have been evaluated specifically for the treatment of NSSI among adolescents. Consequently, child and adolescent clinicians are left with little evidence-based guidance for treating this challenging population. To provide some guidance, evaluations of treatments for adults with NSSI and for adolescents with related conditions, such as deliberate self-harm and borderline personality disorder, are reviewed. Clinical guidelines and resources are also discussed to assist with the gaps in the knowledge base for treatment of NSSI among adolescents.

  18. Psychotherapeutic approaches to non-suicidal self-injury in adolescents.

    Science.gov (United States)

    Washburn, Jason J; Richardt, Sarah L; Styer, Denise M; Gebhardt, Michelle; Juzwin, K R; Yourek, Adrienne; Aldridge, Delia

    2012-03-30

    Non-suicidal self-injury (NSSI) among adolescents is gaining increasing attention in both clinical and scientific arenas. The lifetime prevalence of NSSI is estimated to vary between 7.5% to 8% for preadolescents, increasing to between 12% and 23% for adolescents. Despite the prevalence and the increasing interest in NSSI, few psychotherapeutic treatments have been designed specifically for NSSI, and no treatments have been evaluated specifically for the treatment of NSSI among adolescents. Consequently, child and adolescent clinicians are left with little evidence-based guidance for treating this challenging population. To provide some guidance, evaluations of treatments for adults with NSSI and for adolescents with related conditions, such as deliberate self-harm and borderline personality disorder, are reviewed. Clinical guidelines and resources are also discussed to assist with the gaps in the knowledge base for treatment of NSSI among adolescents.

  19. Experimental Study on Coal-Breaking Pressure for Compressed Air

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    Based on lab model experiments and through the limit analysis, the theoretical formula of calculauoncoal-breaking pressure with compressed air was derived. The experimental result shows that blasting pressure mustexceed 84.0 MPa to break coal with compressive strength of 13.2 MPa. The research provides an important theoretical basis for the design of airshooting mining and industrial tests.

  20. DNA breaks early in replication in B cell cancers

    Science.gov (United States)

    Research by scientists at the NCI has identified a new class of DNA sites in cells that break early in the replication process. They found that these break sites correlate with damage often seen in B cell cancers, such as diffuse large B cell lymphoma.

  1. Mechanisms of supersymmetry breaking in the minimal supersymmetric standard model

    Indian Academy of Sciences (India)

    Probir Roy

    2003-02-01

    We provide a bird’s eyeview of current ideas on supersymmetry breaking mechanisms in the MSSM. The essentials of gauge, gravity, anomaly and gaugino/higgsino mediation mechanisms are covered briefly and the phenomenology of the associated models is touched upon. A few statement are also made on braneworld supersymmetry breaking.

  2. Mediation of Supersymmetry Breaking via Anti-Generation Fields

    CERN Document Server

    Ito, M

    2000-01-01

    In the context of the weakly coupled heterotic string, we propose a new model of mediating supersymmetry breaking. The breakdown of supersymmetry in the hidden sector is transmitted to anti-generation fields via gravitational interactions. Subsequent transmission of the breaking to the MSSM sector occurs via gauge interactions. It is shown that the mass spectra of superparticles are phenomenologically viable.

  3. Inverse Symmetry Breaking and the Exact Renormalization Group

    CERN Document Server

    Pietroni, M; Tetradis, N

    1997-01-01

    We discuss the question of inverse symmetry breaking at non-zero temperature using the exact renormalization group. We study a two-scalar theory and concentrate on the nature of the phase transition during which the symmetry is broken. We also examine the persistence of symmetry breaking at temperatures higher than the critical one.

  4. Spontaneous Breaking of Spatial and Spin Symmetry in Spinor Condensates

    DEFF Research Database (Denmark)

    Scherer, M.; Lücke, B.; Gebreyesus, G.;

    2010-01-01

    Parametric amplification of quantum fluctuations constitutes a fundamental mechanism for spontaneous symmetry breaking. In our experiments, a spinor condensate acts as a parametric amplifier of spin modes, resulting in a twofold spontaneous breaking of spatial and spin symmetry in the amplified...

  5. "Old Dead Guys": Using Activity Breaks to Teach History

    Science.gov (United States)

    Holles, Joseph H.

    2009-01-01

    The people and history of chemical engineering surround us: Gibbs free energy, Arrhenius Equation, and Reynolds number. Since these seminal figures appear in almost every classroom lecture, they provide an opportunity for a historically focused activity break. Each activity break provides the students with an image of the historical figure along…

  6. Shear stresses and mean flow in shoaling and breaking waves

    NARCIS (Netherlands)

    Stive, M.J.F.; De Vriend, H.J.

    1994-01-01

    We investigate the vertical, wave averaged distributions of shear stresses and Eulerian flow in normally incident, shoaling and breaking waves. It is found that shear stresses are solely due to wave amplitude variations, which can be caused by shoaling, boundary layer dissipation and/or breaking wav

  7. Unstable volatility functions: the break preserving local linear estimator

    DEFF Research Database (Denmark)

    Casas, Isabel; Gijbels, Irene

    The objective of this paper is to introduce the break preserving local linear (BPLL) estimator for the estimation of unstable volatility functions. Breaks in the structure of the conditional mean and/or the volatility functions are common in Finance. Markov switching models (Hamilton, 1989) and t...

  8. The Year Zero: Iconoclastic Breaks with the Past

    NARCIS (Netherlands)

    de Baets, Antoon

    2015-01-01

    Some regimes try to force a complete break with the past and even to start from the year zero. Throughout history, such iconoclastic breaks were meant to erase, once and for all, the entire past or to destroy as many of its relics and symbols as possible, and either to reach orregain some faraway go

  9. Distributed Decision Making in Combined Vehicle Routing and Break Scheduling

    NARCIS (Netherlands)

    Meyer, Christoph Manuel; Kopfer, Herbert; Kok, Adrianus Leendert; Schutten, Marco; Kreowski, Hans-Jörg; Scholz-Reiter, Bernd; Thoben, Klaus-Dieter

    2011-01-01

    The problem of combined vehicle routing and break scheduling comprises three subproblems: clustering of customer requests, routing of vehicles, and break scheduling. In practice, these subproblems are usually solved in the interaction between planners and drivers. We consider the case that the plann

  10. Distributed Decision Making in Combined Vehicle Routing and Break Scheduling

    NARCIS (Netherlands)

    Meyer, Christoph Manuel; Kopfer, Herbert; Kok, Adrianus Leendert; Schutten, Marco

    2009-01-01

    The problem of combined vehicle routing and break scheduling comprises three subproblems: clustering of customer requests, routing of vehicles, and break scheduling. In practice, these subproblems are usually solved in the interaction between planners and drivers. We consider the case that the plann

  11. ANALYSIS OF MEN'S AND WOMEN'S BASKETBALL FAST-BREAKS

    Directory of Open Access Journals (Sweden)

    Ignacio Refoyo

    2009-01-01

    opposition. For men, some dependence relationships were found between the fast break result and the following variables: duration, completion area, and opposition to its completion. For women, the results revealed a weak association between the fast break result and the opposition to its completion.

  12. Examining structural breaks and growth rates in international health expenditures.

    Science.gov (United States)

    Narayan, Paresh Kumar

    2006-09-01

    Over the last decade, there has been a growing interest in examining health expenditures. In this paper, we study the behaviour of health expenditures in the G3 countries (USA, the UK, and Japan) and three European countries (the UK, Switzerland and Spain) over the period 1960-2000 from a different perspective, in that we examine: (1) whether there is a common structural break in health expenditures across the G3 and European countries; (2) whether structural breaks have slowed down health expenditure growth rates in these countries or vice versa. Our main findings are that: (1) health expenditures share a common break in both bivariate and trivariate cases, and structural breaks and break intervals suggest that either one or a combination of events (second oil price shock, the 1987 stock market crash and/or recessions) have contributed to the commonality of break in health expenditures in the G3, while the oil price shocks have been instrumental in the commonality of breaks for the European countries; (2) except for the UK, structural breaks have slowed down growth rates in health expenditures for the USA, Japan, Switzerland and Spain.

  13. Young Children's Interpretations of Page Breaks in Contemporary Picture Storybooks

    Science.gov (United States)

    Sipe, Lawrence R.; Brightman, Anne E.

    2009-01-01

    This article reports on a study of the responses of a second-grade class to the page breaks in contemporary picturebooks. In a picturebook, the text and accompanying illustrations are divided into a series of facing pages called openings, and the divisions between the openings are called page breaks or turns. Unlike a novel, in which the page…

  14. Treated Effluent Disposal Facility

    Data.gov (United States)

    Federal Laboratory Consortium — Treated non-hazardous and non-radioactive liquid wastes are collected and then disposed of through the systems at the Treated Effluent Disposal Facility (TEDF). More...

  15. How Is Anemia Treated?

    Science.gov (United States)

    ... such as beef or liver), as well as chicken, turkey, pork, fish, and shellfish. Nonmeat foods that ... cause of anemia. Some of these medicines include: Antibiotics to treat infections. Hormones to treat heavy menstrual ...

  16. Adolescent attachment and psychopathology.

    Science.gov (United States)

    Rosenstein, D S; Horowitz, H A

    1996-04-01

    The relationships among attachment classification, psychopathology, and personality traits were examined in a group of 60 psychiatrically hospitalized adolescents. The concordance of attachment classification was examined in 27 adolescent-mother pairs. Both adolescent and maternal attachment status were overwhelmingly insecure and were highly concordant. Adolescents showing a dismissing attachment organization were more likely to have a conduct or substance abuse disorder, narcissistic or antisocial personality disorder, and self-reported narcissistic, antisocial, and paranoid personality traits. Adolescents showing a preoccupied attachment organization were more likely to have an affective disorder, obsessive-compulsive, histrionic, borderline or schizotypal personality disorder, and self-reported avoidant, anxious, and dysthymic personality traits. The results support a model of development of psychopathology based partially on relational experiences with parents.

  17. Rural female adolescence: Indian scenario.

    Science.gov (United States)

    Kumari, R

    1995-01-01

    This article describes the life conditions of female adolescents in India and issues such as health, discrimination in nutrition and literacy, child labor, early marriage, juvenile delinquency, and violence against girls in rural areas of India. Data are obtained from interview samples conducted among 12 villages in north India. Female adolescents suffer from a variety of poverty-ridden village life conditions: caste oppression, lack of facilities, malnutrition, educational backwardness, early marriage, domestic burden, and gender neglect. Girls carry a heavy work burden. Adolescence in rural areas is marked by the onset of puberty and the thrust into adulthood. Girls have no independent authority to control their sexuality or reproduction. Girls are expected to get married and produce children. Control of female sexuality is shifted from the father to the husband. There is a strong push to marry girls soon after menstruation, due to the burden of imposing strict restrictions on female sexuality, the desire to reduce the burden of financial support, and the need to ensure social security for daughters. Girls may not go out alone or stay outside after dark. Many rural parents fear that education and freedom would ruin their daughter. Girls develop a low self-image. Rural villages have poor sanitation, toilet facilities, and drainage systems. Girls are ignorant of health and sex education and lack access to education. The neglect of female children includes malnutrition, sex bias, and early marriage. In 1981, almost 4 out of every 100 girls had to work. 5.527 million girls 5-14 years old were child laborers. Girls are veiled, footbound, circumcised, and burnt by dowry hungry in-laws. Female delinquents are subjected to sexual harassment and sometime to sexual abuse while in custody. Cows are treated better in rural India than women. Gender disparity is caused by the perpetuation of patriarchal masculine values.

  18. The blues of adolescent romance: observed affective interactions in adolescent romantic relationships associated with depressive symptoms.

    Science.gov (United States)

    Ha, Thao; Dishion, Thomas J; Overbeek, Geertjan; Burk, William J; Engels, Rutger C M E

    2014-05-01

    We examined the associations between observed expressions of positive and negative emotions during conflict discussions and depressive symptoms during a 2-year period in a sample of 160 adolescents in 80 romantic relationships (M age = 15.48, SD = 1.16). Conflict discussions were coded using the 10-code Specific Affect Coding System. Depressive symptoms were assessed at the time of the observed conflict discussions (Time 1) and 2 years later (Time 2). Data were analyzed using actor-partner interdependence models. Girls' expression of both positive and negative emotions at T1 was related to their own depressive symptoms at T2 (actor effect). Boys' positive emotions and negative emotions (actor effect) and girls' negative emotions (partner effect) were related to boys' depressive symptoms at T2. Contrary to expectation, relationship break-up and relationship satisfaction were unrelated to changes in depressive symptoms or expression of negative or positive emotion during conflict discussion. These findings underscore the unique quality of adolescent romantic relationships and suggest new directions in the study of the link between mental health and romantic involvement in adolescence.

  19. Dynamical Electroweak Symmetry Breaking from Extra Dimensions

    CERN Document Server

    Hashimoto, M; Yamawaki, K; Hashimoto, Michio; Tanabashi, Masaharu; Yamawaki, Koichi

    2003-01-01

    We study the dynamical electroweak symmetry breaking (DEWSB) in the $D (=6,8,...)$-dimensional bulk with compactified extra dimensions. We identify the critical binding strength for triggering the DEWSB, based on the ladder Schwinger-Dyson equation. In the top mode standard model with extra dimensions, where the standard model gauge bosons and the third generation of quarks and leptons are put in the bulk, we analyze the most attractive channel (MAC) by using renormalization group equations (RGEs) of (dimensionless) bulk gauge couplings and determine the effective cutoff where the MAC coupling exceeds the critical value. We then find that the top-condensation can take place for D=8. Combining RGEs of top-Yukawa and Higgs-quartic couplings with compositeness conditions, we predict the top mass, $m_t=173-180$ GeV, and the Higgs mass, $m_H=181-211$ GeV, for D=8, where we took the universal compactification scale $1/R = 1-100$ TeV.

  20. Dynamical Electroweak Symmetry Breaking from Extra Dimensions

    Science.gov (United States)

    Hashimoto, Michio; Tanabashi, Masaharu; Yamawaki, Koichi

    2003-08-01

    We study the dynamical electroweak symmetry breaking (DEWSB) in the D(= 6, 8, ⋯)-dimensional bulk with compactified extra dimensions. We identify the critical binding strength for triggering the DEWSB, based on the ladder Schwinger-Dyson equation. In the top mode standard model with extra dimensions, where the standard model gauge bosons and the third generation of quarks and leptons are put in the bulk, we analyze the most attractive channel (MAC) by using renormalization group equations (RGEs) of (dimensionless) bulk gauge couplings and determine the effective cutoff where the MAC coupling exceeds the critical value. We then find that the top-condensation can take place for D = 8. Combining RGEs of top-Yukawa and Higgs-quartic couplings with compositeness conditions, we predict the top mass, mt = 173 - 180 GeV, and the Higgs mass, mH = 181 - 211 GeV, for D = 8, where we took the universal compactification scale 1/R = 1 - 100 TeV.

  1. Generalized geometry and partial supersymmetry breaking

    Energy Technology Data Exchange (ETDEWEB)

    Triendl, Hagen Mathias

    2010-08-15

    This thesis consists of two parts. In the first part we use the formalism of (exceptional) generalized geometry to derive the scalar field space of SU(2) x SU(2)-structure compactifications. We show that in contrast to SU(3) x SU(3) structures, there is no dynamical SU(2) x SU(2) structure interpolating between an SU(2) structure and an identity structure. Furthermore, we derive the scalar manifold of the low-energy effective action for consistent Kaluza-Klein truncations as expected from N = 4 supergravity. In the second part we then determine the general conditions for the existence of stable Minkowski and AdS N = 1 vacua in spontaneously broken gauged N = 2 supergravities and construct the general solution under the assumption that two appropriate commuting isometries exist in the hypermultiplet sector. Furthermore, we derive the low-energy effective action below the scale of partial supersymmetry breaking and show that it satisfies the constraints of N = 1 supergravity. We then apply the discussion to special quaternionic-Kaehler geometries which appear in the low-energy limit of SU(3) x SU(3)-structure compactifications and construct Killing vectors with the right properties. Finally we discuss the string theory realizations for these solutions. (orig.)

  2. Breaking temporal symmetries for emission and absorption

    Science.gov (United States)

    Hadad, Yakir; Soric, Jason C.; Alu, Andrea

    2016-01-01

    Time-reversal symmetries impose stringent constraints on emission and absorption. Antennas, from radiofrequencies to optics, are bound to transmit and receive signals equally well from the same direction, making a directive antenna prone to receive echoes and reflections. Similarly, in thermodynamics Kirchhoff’s law dictates that the absorptivity and emissivity are bound to be equal in reciprocal systems at equilibrium, e(ω,θ)=a(ω,θ), with important consequences for thermal management and energy applications. This bound requires that a good absorber emits a portion of the absorbed energy back to the source, limiting its overall efficiency. Recent works have shown that weak time modulation or mechanical motion in suitably designed structures may largely break reciprocity and time-reversal symmetry. Here we show theoretically and experimentally that a spatiotemporally modulated device can be designed to have drastically different emission and absorption properties. The proposed concept may provide significant advances for compact and efficient radiofrequency communication systems, as well as for energy harvesting and thermal management when translated to infrared frequencies. PMID:26984502

  3. LHC Report: a break from luminosity production

    CERN Multimedia

    Jan Uythoven for the LHC team

    2016-01-01

    The LHC has been in great shape over the last few months, delivering over 20 fb-1 of integrated luminosity before the ICHEP conference in Chicago at the beginning of August. This is not much below the 25 fb-1 target for the whole of 2016. With this success in mind, a break in luminosity production was taken for six days, starting on 26 July 2016, for a machine development period.   This year, 20 days of the LHC schedule are devoted to machine development with the aim of carrying out detailed studies of the accelerator. The 20 days are divided over five different periods, called MD blocks. They can be seen as an investment in the future, so the machine can produce collisions more efficiently in the months and years to come. A detailed programme is worked out for each MD block, whereby different specialist teams are assigned periods of four to twelve hours, depending on the topic, to perform their previously approved tests. The MD program continues 24 hours per day, as in normal physics operation. One...

  4. Parametric Symmetry Breaking in a Nonlinear Resonator

    Science.gov (United States)

    Leuch, Anina; Papariello, Luca; Zilberberg, Oded; Degen, Christian L.; Chitra, R.; Eichler, Alexander

    2016-11-01

    Much of the physical world around us can be described in terms of harmonic oscillators in thermodynamic equilibrium. At the same time, the far-from-equilibrium behavior of oscillators is important in many aspects of modern physics. Here, we investigate a resonating system subject to a fundamental interplay between intrinsic nonlinearities and a combination of several driving forces. We have constructed a controllable and robust realization of such a system using a macroscopic doubly clamped string. We experimentally observe a hitherto unseen double hysteresis in both the amplitude and the phase of the resonator's response function and present a theoretical model that is in excellent agreement with the experiment. Our work unveils that the double hysteresis is a manifestation of an out-of-equilibrium symmetry breaking between parametric phase states. Such a fundamental phenomenon, in the most ubiquitous building block of nature, paves the way for the investigation of new dynamical phases of matter in parametrically driven many-body systems and motivates applications ranging from ultrasensitive force detection to low-energy computing memory units.

  5. Control of roofs difficult to break down

    Energy Technology Data Exchange (ETDEWEB)

    Lukashov, V.G.; Suslyakov, V.P.; Korobov, A.N.

    1981-03-01

    This paper describes a method of advanced torpedoing a roof difficult to break down at the Polysaevskaya coal mine. It consists in placing explosive charges in the roof ahead of the coal face. Three schemes were tested: boreholes were drilled parallel to the face, perpendicular or inclined at an angle to the face. Boreholes were 112 mm in diameter and their length ranged from 30 to 100 m, distance between the boreholes amounted to 20 m. 6ZhV ammonite explosive, 90 mm in diameter and 500 mm long, were used. Torpedos were 2 m long, and separated by 3 to 4 m long air pockets. When a roof characterized by a high compressive strength coefficient (about 10 on the Protod'yakonov scale) was torpedoed, 250 kg of ammonite were used for a borehole 80 m long, and 160 kg for a borehole 50 m long. When borehole length was reduced to 40 m explosive consumption decreased to 117 kg. In the case of rocks with compressive strength coefficient of 6, explosive amount was two times lower. In a coal mine in which an OKP-70 face system was used applying advanced torpedoing increased labor productivity of the face by 30% and reduced cost of mining by 42%. Number of work accidents was reduced 13 times. (In Russian)

  6. Golden Probe of Electroweak Symmetry Breaking

    CERN Document Server

    Chen, Yi; Spiropulu, Maria; Stolarski, Daniel; Vega-Morales, Roberto

    2016-01-01

    The ratio of the Higgs couplings to $WW$ and $ZZ$ pairs, $\\lambda_{WZ}$, is a fundamental parameter in electroweak symmetry breaking as well as a measure of the (approximate) custodial symmetry possessed by the gauge boson mass matrix. We show that Higgs decays to four leptons are sensitive, via tree level/1-loop interference effects, to both the magnitude and, in particular, overall sign of $\\lambda_{WZ}$. Determining this sign requires interference effects, as it is nearly impossible to measure with rate information. Furthermore, simply determining the sign effectively establishes the custodial representation of the Higgs boson. We find that $h\\to4\\ell$ ($4\\ell \\equiv 2e2\\mu, 4e, 4\\mu$) decays have excellent prospects of directly establishing the overall sign at a high luminosity 13 TeV LHC. We also examine the ultimate LHC sensitivity in $h\\to4\\ell$ to the magnitude of $\\lambda_{WZ}$. Our results are independent of other measurements of the Higgs boson couplings and, in particular, largely free of assumpti...

  7. Kinematic Dynamo, Supersymmetry Breaking, and Chaos

    CERN Document Server

    Ovchinnikov, Igor V

    2015-01-01

    The kinematic dynamo (KD) describes the growth of magnetic fields generated by the flow of a conducting medium in the limit of vanishing backaction of the fields onto the flow. The KD is therefore an important model system for understanding astrophysical magnetism. Here, the mathematical correspondence between the KD and a specific stochastic differential equation (SDE) viewed from the perspective of the supersymmetric theory of stochastics (STS) is discussed. The STS is a novel, approximation-free framework to investigate SDEs. The correspondence reported here permits insights from the STS to be applied to the theory of KD and vice versa. It was previously known that the fast KD in the idealistic limit of no magnetic diffusion requires chaotic flows. The KD-STS correspondence shows that this is also true for the diffusive KD. From the STS perspective, the KD possesses a topological supersymmetry and the dynamo effect can be viewed as its spontaneous breakdown. This supersymmetry breaking can be regarded as t...

  8. Warped electroweak breaking without custodial symmetry

    Science.gov (United States)

    Cabrer, Joan A.; von Gersdorff, Gero; Quirós, Mariano

    2011-03-01

    We propose an alternative to the introduction of an extra gauge (custodial) symmetry to suppress the contribution of KK modes to the T parameter in warped theories of electroweak breaking. The mechanism is based on a general class of warped 5D metrics and a Higgs propagating in the bulk. The metrics are nearly AdS in the UV region but depart from AdS in the IR region, towards where KK fluctuations are mainly localized, and have a singularity outside the slice between the UV and IR branes. This gravitational background is generated by a bulk stabilizing scalar field which triggers a natural solution to the hierarchy problem. Depending on the model parameters, gauge-boson KK modes can be consistent with present bounds on EWPT for mKK≳1 TeV at 95% CL. The model contains a light Higgs mode which unitarizes the four-dimensional theory. The reduction in the precision observables can be traced back to a large wave function renormalization for this mode.

  9. Warped Electroweak Breaking Without Custodial Symmetry

    CERN Document Server

    Cabrer, Joan A; Quiros, Mariano

    2010-01-01

    We propose an alternative to the introduction of an extra gauge (custodial) symmetry to suppress the contribution of KK modes to the T parameter in warped theories of electroweak breaking. The mechanism is based on a general class of warped 5D metrics and a Higgs propagating in the bulk. The metrics are nearly AdS in the UV region but depart from AdS in the IR region, towards where KK fluctuations are mainly localized, and have a singularity outside the slice between the UV and IR branes. This gravitational background is generated by a bulk stabilizing scalar field which triggers a natural solution to the hierarchy problem. Depending on the model parameters, gauge-boson KK modes can be consistent with present bounds on EWPT for m > 1 TeV at 95% CL. The model contains a light Higgs mode which unitarizes the four-dimensional theory. The reduction in the precision observables can be traced back to a large wave function renormalization for this mode.

  10. Self-breaking retarded acid emulsion

    Energy Technology Data Exchange (ETDEWEB)

    Scherubel, G.A.

    1980-10-07

    An acid-in-oil acidizing emulsion, and acidizing method use an emulsion of the type containing an effective amount of at least one C8 to C18 primary amine as a cationic surfactant to increase the normal reaction time of the acid with an acid soluble formation. The composition and method aspects are both affected by the inclusion in the emulsion of an effective amount of a nonionic surfactant. Specifically, the emulsion resides in a composition for acidizing a subterranean formation, the composition being of the acidizing solution-in-oil emulsion type containing an effective amount of an alkyl C8 to C18 primary amine to reduce the normal reaction rate of the emulsion, and an effective amount of at least one diethanolamide of at least one C8 to C18 fatty acid so that the emulsion substantially completely breaks when the acidizing capacity of the emulsion becomes substantially spent as a result of reaction with such a formation. 19 claims.

  11. A Molecular Model for Chiral Symmetry Breaking

    Science.gov (United States)

    Latinwo, Folarin; Stillinger, Frank; Debenedetti, Pablo

    In this work, we present a new class of molecular models for chiral phenomena in condensed matter systems. A key feature of these models is the ability of the four-site (tetramer) ``molecules'' to inter-convert between two distinct chiral forms (enantiomers). Given this feature, we use analytical theory and computer simulations to investigate the emergent chiral properties (including symmetry breaking) over a range of conditions. In particular, we consider the single-molecule level and condensed-phase behavior of our model system. Interestingly, we find that our liquid-phase predictions are in excellent agreement with recent experimental reports on chiral self-sorting in isotropic liquids. From this perspective, our model demonstrates accurate predictive capabilities, as well as a platform for understanding the microscopic origins of a variety of chiral phenomena. In a broader context, we anticipate that this class of models will be relevant to chirality-dominated areas such as the pharmaceutical industry and pre-biotic geochemistry.

  12. Spontaneous Planar Chiral Symmetry Breaking in Cells

    Science.gov (United States)

    Hadidjojo, Jeremy; Lubensky, David

    Recent progress in animal development has highlighted the central role played by planar cell polarity (PCP) in epithelial tissue morphogenesis. Through PCP, cells have the ability to collectively polarize in the plane of the epithelium by localizing morphogenetic proteins along a certain axis. This allows direction-dependent modulation of tissue mechanical properties that can translate into the formation of complex, non-rotationally invariant shapes. Recent experimental observations[1] show that cells, in addition to being planar-polarized, can also spontaneously develop planar chirality, perhaps in the effort of making yet more complex shapes that are reflection non-invariant. In this talk we will present our work in characterizing general mechanisms that can lead to spontaneous chiral symmetry breaking in cells. We decompose interfacial concentration of polarity proteins in a hexagonal cell packing into irreducible representations. We find that in the case of polar concentration distributions, a chiral state can only be reached from a secondary instability after the cells are polarized. However in the case of nematic distributions, we show that a finite-amplitude (subcritical, or ``first-order'') nematic transition can send the system from disorder directly to a chiral state. In addition, we find that perturbing the system by stretching the hexagonal packing enables direct (supercritical, or ``second-order'') chiral transition in the nematic case. Finally, we do a Landau expansion to study competition between stretch-induced chirality and the tendency towards a non-chiral state in packings that have retained the full 6-fold symmetry.

  13. Contrasting effects of interference and of breaks in interval timing.

    Science.gov (United States)

    Gaudreault, Rémi; Fortin, Claudette; Macar, Françoise

    2010-01-01

    When a break is introduced during an interval to be timed, the interval is perceived shorter as break location is delayed. This is interpreted as a result of attention sharing between timing and monitoring the source of the break signal. Similar effects and interpretations are found in another context involving interfering tasks. Such tasks are assumed to induce transient interruptions in timing, comparable to those obtained with breaks. Break and interference conditions were contrasted in a temporal reproduction procedure with identical stimuli. Both conditions induced temporal underestimation and similar location effects. Similar trends occurred in a control condition where no processing of the interfering signal was required. The data suggest that expectancy, intentional processing, and automatic attraction of attention shorten temporal estimates.

  14. A Supersymmetric Composite Model with Dynamical Supersymmetry Breaking

    CERN Document Server

    Kitazawa, N; Kitazawa, Noriaki; Okada, Nobuchika

    1997-01-01

    We present a supersymmetric composite model with dynamical supersymmetry breaking. The model is based on the gauge group $SU(2)_S \\times SU(2)_H \\times SU(3)_c \\times SU(2)_L \\times U(1)_Y$. Supersymmetry is dynamically broken by the non-perturbative effect of the $SU(2)_S$ `supercolor' interaction. The large top Yukawa coupling is naturally generated by the $SU(2)_H$ `hypercolor' interaction as recently proposed by Nelson and Strassler. The supersymmetry breaking is mediated to the standard model sector by a new mechanism. The electroweak symmetry breaking is caused by the radiative correction due to the large top Yukawa coupling with the supersymmetry breaking. This is the `radiative breaking scenario', which originates from the dynamics of the supercolor and hypercolor gauge interactions.

  15. ANALISA BREAK EVENT POINT (BEP TERHADAP LABA PERUSAHAAN

    Directory of Open Access Journals (Sweden)

    Muhammad Yusuf

    2015-09-01

    Full Text Available Break event point or the break-even point can be defined as a situation where the operating company does not make a profit and not a loss. The goal is to provide the knowledge to increase knowledge about the break event point (the point of principal and its relationship with the company profit and to know how the results of the. Analysis break event point is very important for the leadership of the company to determine the production rate how much the cost will be equal to the amount of sales or in other words to determine the break event point we will determine the relationship between sales, production, selling price, cost, loss or profit, making it easier for leaders to take discretion.DOI: 10.15408/ess.v4i1.1955 

  16. Incidence of cervical intraepithelial lesions in a population of adolescents treated in public health services in Rio de Janeiro, Brazil Incidência de lesões intra-epiteliais cervicais em população de adolescentes atendidas em serviço público de saúde no Rio de Janeiro, Brasil

    Directory of Open Access Journals (Sweden)

    Denise Leite Maia Monteiro

    2009-05-01

    Full Text Available This study aimed to estimate the incidence and types of cervical cytopathological findings in adolescents who were treated in public health services between 1993 and 2006. This is a cohort study, with the following inclusion criteria: O objetivo foi estimar a incidência e os tipos das alterações citopatológicas cervicais em adolescentes acompanhadas em serviço público entre 1993-2006. Estudo de coorte, tendo como critérios de inclusão: idade < 20 anos, apresentar atividade sexual, citopatologia negativa para lesão cervical na entrada do estudo ou tempo de atividade sexual <1 ano. Os dados foram coletados de prontuários de 403 adolescentes. Foi estimada densidade de incidência, e para o cálculo da incidência das alterações citopatológicas referentes a cinco anos de acompanhamento após atividade sexual foi utilizado o método atuarial. No primeiro ano de atividade sexual, a incidência de lesões cervicais foi de 24,1%. Houve redução da incidência nos quatro anos subseqüentes com variação entre 3-8%. A densidade de incidência foi de 4,7 casos/100 pessoas-ano. O primeiro diagnóstico citológico anormal mostrou atipias em células escamosas de significado indeterminado (ASCUS em 5,5% (22 das pacientes, lesão intra-epitelial escamosa de baixo grau (LSIL em 28% (113 e lesão intra-epitelial escamosa de alto grau (HSIL em 3% (12. Oito (67% dos casos de HSIL ocorreram no primeiro ano de atividade sexual. A incidência de alterações citopatológicas é alta no início da vida sexual, sugerindo ser importante a inclusão das adolescentes sexualmente ativas no Programa de Controle do Câncer de Colo Uterino.

  17. Risperidone-induced symptomatic hyperprolactinaemia in adolescents.

    Science.gov (United States)

    Holzer, Laurent; Eap, Chin B

    2006-04-01

    Studies performed in adult patients unambiguously demonstrate a marked effect of risperidone on prolactin blood levels, with possible clinical effects related to hyperprolactinemia, such as gynecomastia and galactorrhea. However, the largest study performed in children and adolescents showed a weak effect of risperidone on prolactin concentrations during short-term treatment and a negligible effect during long-term treatment, which was probably because of the relatively low dosages of risperidone used [approximately 0.04 mg/(kg x d)]. Among the 10 psychotic adolescents treated with risperidone in our unit, we had 3 cases of gynecomastia in 3 male patients and 2 cases of galactorrhea in 2 female patients. The prolactin blood levels in these cases and in 3 other patients without apparent prolactin-related side effects were all above the normal range (median, 59 ng/mL; range, 30-123 ng/mL). Thus, risperidone administered to adolescents at doses commonly used for the treatment of psychotic symptoms can strongly increase prolactin levels, with clinical consequences such as gynecomastia and/or galactorrhea. Given that the long-term effects of antipsychotic drug-induced hyperprolactinemia are not well documented, especially regarding osteopenia, infertility, growth, and pubertal delay, risperidone should be administered with caution to children and adolescents.

  18. Refeeding Hypophosphatemia in Adolescents With Anorexia Nervosa

    Science.gov (United States)

    Nicholls, Dasha

    2013-01-01

    The rate of adolescents presenting with anorexia nervosa (AN) is increasing. Medically unstable adolescents are admitted to the hospital for nutrition restoration. A lack of global consensus on appropriate refeeding practices of malnourished patients has resulted in inconsistent refeeding practices. Refeeding hypophosphatemia (RH) is the most common complication associated with refeeding the malnourished patient. This review sought to identify the range of refeeding rates adopted globally and the implication that total energy intake and malnutrition may have on RH while refeeding adolescents with anorexia nervosa. Studies were identified by a systematic electronic search of medical databases from 1980 to September 2012. Seventeen publications were identified, including 6 chart reviews, 1 observational study, and 10 case reports, with a total of 1039 subjects. The average refeeding energy intake was 1186 kcal/d, ranging from 125–1900 kcal/d, with a mean percentage median body mass index (% mBMI) of 78%. The average incidence rate of RH was 14%. A significant correlation between malnutrition (% mBMI) and post-refeeding phosphate was identified (R 2 = 0.6, P = .01). This review highlights the disparity in refeeding rates adopted internationally in treating malnourished adolescents with anorexia nervosa. Based on this review, the severity of malnutrition seems to be a marker for the development of RH more so than total energy intake. PMID:23459608

  19. Adolescent sexuality and its problems.

    Science.gov (United States)

    Yang, M

    1995-09-01

    Adolescent sexual activity is increasing globally. Abstinence and a delay in the start of sexual intercourse may be the most effective methods in preventing the consequences of teenage sexual activity. However, these goals are seldom met. With the change in social norms, peer pressure and media influences; teenagers are engaging in premarital sex earlier. Family life education in countries like Sweden and Finland reduces teenage pregnancy and abortion. It is unrealistic to expect sexually active adolescents to stop their sexual activity. An effective contraceptive method will provide an alternative to prevent teenage pregnancy. Issues on compliance of contraceptive use, especially at the very outset of sexual activity should be addressed. Most of the problems associated with teenage pregnancy are now thought to be related to the social circumstances of the mother, the poor nutritional status before pregnancy and poor attendance at antenatal clinics. Risk-taking behaviour in this age group will also make them more prone to contracting sexually transmitted diseases. High risk groups should be screened and treated early. Contraceptive methods with protection against sexually transmitted diseases should be advised.

  20. Spectra of massive QCD Dirac Operators from Random Matrix Theory all three chiral symmetry breaking patterns

    CERN Document Server

    Akemann, G

    2001-01-01

    The microscopic spectral eigenvalue correlations of QCD Dirac operators in the presence of dynamical fermions are calculated within the framework of Random Matrix Theory (RMT). Our approach treats the low--energy correlation functions of all three chiral symmetry breaking patterns (labeled by the Dyson index $\\beta=1,2$ and 4) on the same footing, offering a unifying description of massive QCD Dirac spectra. RMT universality is explicitly proven for all three symmetry classes and the results are compared to the available lattice data for $\\beta=4$.

  1. Adolescent and Parental Contributions to Parent-Adolescent Hostility Across Early Adolescence.

    Science.gov (United States)

    Weymouth, Bridget B; Buehler, Cheryl

    2016-04-01

    Early adolescence is characterized by increases in parent-adolescent hostility, yet little is known about what predicts these changes. Utilizing a fairly large sample (N = 416, 51 % girls, 91 % European American), this study examined the conjoint and unique influences of adolescent social anxiety symptoms and parental intrusiveness on changes in parent-adolescent hostility across early adolescence. Higher mother and father intrusiveness were associated with increased mother- and father-adolescent hostility. An examination of reciprocal effects revealed that mother- and father-adolescent hostility predicted increased mother and father intrusiveness. Significant associations were not substantiated for adolescent social anxiety symptoms. These findings suggest that intrusive parenting has important implications for subsequent parent-adolescent interactions and that similar patterns may characterize some aspects of mother- and father-adolescent relationships.

  2. The anaplastic cancer of the child and adolescent cavum in East Algeria. About 284 cases treated at the Benbadis university hospital center of Constantine. Results at long term; Le cancer indifferencie du cavum chez l'enfant et l'adolescent de l'est algerien. A propos de 284 cas traites au centre hospitalier universitaire Benbadis de Constantine. Resultats a long terme

    Energy Technology Data Exchange (ETDEWEB)

    Sahli, B.; Bali, M.S.; Meziane, A.; Merikhi, T.; Djemaa, A. [CHU Benbadis, Service d' Oncologie-Radiotherapie, Constantine (Algeria)

    2009-10-15

    The naso-pharynx cancer in child and adolescent is often diagnosed when it is locally evolved, a multimodal treatment allows a to get a better local control rate with an acceptable early toxicity comparable to the adult's one but with more late toxicity. The introduction of of new chemotherapy drugs and the use of new radiotherapy techniques will certainly allow to improve the results and to reduce the complications. (N.C.)

  3. Teaching adolescents about adolescence: experiences from an interdisciplinary adolescent health course.

    Science.gov (United States)

    Aronowitz, Teri

    2006-01-01

    As abstract reasoning increases in complexity, adolescents may face dissonance between new thoughts and prior beliefs. Students in the health professions may be forced to resolve these dissonances in order to execute their professional responsibilities. In developing an undergraduate interdisciplinary course on adolescent health, the authors anticipated challenges in teaching adolescents about adolescence. Over the course of the semester, the anticipated challenges became reality. The author discusses pertinent developmental theories and their application in facilitating late adolescent identity formation and professional role development.

  4. 3D Simulation of Dam-break effect on a Solid Wall using Smoothed Particle Hydrodynamics

    CERN Document Server

    Suprijadi,; Naa, Christian; Putra, Anggy Trisnawan

    2013-01-01

    Dam is built for water supply, water flow or flooding control and electricity energy storage, but in other hand, dam is one of the most dangerous natural disaster in many countries including in Indonesia. The impact of dam break in neighbour area and is huge and many flooding in remote area, as happen in Dam Situ Gintung in Tangerang (close to Jakarta) in 2009. Smoothed Particle Hydrodynamics (SPH), is one of numerical method based on Lagrangian grid which is ap- plied in astrophysical simulation may be used to solve the simulation on dam break effect. The development of SPH methods become alternative methods to solving Navier Stokes equation, which is main key in fluid dynamic simulation. In this paper, SPH is developed for supporting solid par- ticles in use for 3D dam break effect (3D-DBE) simulation. Solid particle have been treated same as fluid particles with additional calculation for converting gained position became translation and rotation of solid object in a whole body. With this capability, the r...

  5. Electronic cigarettes induce DNA strand breaks and cell death independently of nicotine in cell lines

    Science.gov (United States)

    Yu, Vicky; Rahimy, Mehran; Korrapati, Avinaash; Xuan, Yinan; Zou, Angela E.; Krishnan, Aswini R.; Tsui, Tzuhan; Aguilera, Joseph A.; Advani, Sunil; Crotty Alexander, Laura E.; Brumund, Kevin T.; Wang-Rodriguez, Jessica

    2016-01-01

    Objectives Evaluate the cytotoxicity and genotoxicity of short- and long-term e-cigarette vapor exposure on a panel of normal epithelial and head and neck squamous cell carcinoma (HNSCC) cell lines. Materials and Methods HaCaT, UMSCC10B, and HN30 were treated with nicotine-containing and nicotine-free vapor extract from two popular e-cigarette brands for periods ranging from 48 hours to 8 weeks. Cytotoxicity was assessed using Annexin V flow cytometric analysis, trypan blue exclusion, and clonogenic assays. Genotoxicity in the form of DNA strand breaks was quantified using the neutral comet assay and γ-H2AX immunostaining. Results E-cigarette-exposed cells showed significantly reduced cell viability and clonogenic survival, along with increased rates of apoptosis and necrosis, regardless of e-cigarette vapor nicotine content. They also exhibited significantly increased comet tail length and accumulation of γ-H2AX foci, demonstrating increased DNA strand breaks. Conclusion E-cigarette vapor, both with and without nicotine, is cytotoxic to epithelial cell lines and is a DNA strand break-inducing agent. Further assessment of the potential carcinogenic effects of e-cigarette vapor is urgently needed. PMID:26547127

  6. The implementation of the algorithm of break surface simulation while designing the well breaking

    Directory of Open Access Journals (Sweden)

    Lukichev S.V.

    2015-06-01

    Full Text Available A method of calculating the break surface formed as a result of blast-hole rings' short-delay blasting has been developed. The method is based on simulation modeling of a process of broken rock separation from rock mass. A modeling tool has been implemented as a part of the module for designing cave large-scale blasts included in MINEFRAME software package. It has been shown that the tool can evaluate possible outcomes of the project of cave large-scale blast properly

  7. Atopic dermatitis in adolescence

    Directory of Open Access Journals (Sweden)

    Giampaolo Ricci

    2011-12-01

    Full Text Available Atopic dermatitis (AD is a chronic inflammatory skin disorder that typically occurs during childhood especially in the first year of life, with a variable frequency from 10% to 30%. Recent studies have shown that in Europe among 10-20% of children with AD suffer from this disorder also in adolescence. AD is a chronic inflammatory skin disease with a typical onset in the first years of life and with a 10- 30% prevalence among young children. AD prevalence in adolescence has been estimated around 5-15% in European countries. AD persists from childhood through adolescence in around 40% of cases and some risk factors have been identified: female sex, sensitization to inhalant and food allergens, allergic asthma and/or rhinoconjunctivitis, the practice of certain jobs. During adolescence, AD mainly appears on the face and neck, often associated with overinfection by Malassezia, and on the palms and soles. AD persistence during adolescence is correlated with psychological diseases such as anxiety; moreover, adolescents affected by AD might have problems in the relationship with their peers. Stress and the psychological problems represent a serious burden for adolescents with AD and cause a significant worsening of the patients’ quality of life (QoL. The pharmacological treatment is similar to other age groups. Educational and psychological approaches should be considered in the most severe cases.

  8. Breaking Bad News to Togolese Patients.

    Science.gov (United States)

    Kpanake, Lonzozou; Sorum, Paul Clay; Mullet, Etienne

    2016-11-01

    The aim of this study was to map Togolese people's positions regarding the breaking of bad news to elderly patients. Two hundred eleven participants who had in the past received bad medical news were presented with 72 vignettes depicting communication of bad news to elderly female patients and asked to indicate the acceptability of the physician's conduct in each case. The vignettes were all combinations of five factors: (a) the severity of the disease, (b) the patient's wishes about disclosure, (c) the level of social support during hospitalization, (d) the patient's psychological robustness, and (e) the physician's decision about how to communicate the bad news. Five qualitatively different positions were found. Two percent of the participants preferred that the physician always tell the full truth to both the patient and her relatives, 8% preferred that the truth be told depending on the physician's perception of the situation, 15% preferred that the physician tell the truth but understood that in some cases nondisclosure to the patient was not inappropriate, 33% preferred that the physician tell the full truth to the relatives but not as much information to the patient, and 42% preferred that the physician tell the full truth to the relatives only. These findings present a challenge to European physicians taking care of African patients living in Europe or working in African hospitals, and to African physicians trained in Europe and now working in their home countries. If these physicians respect the imperative of always telling the truth directly to their patients, their behavior may trigger anger and considerable misunderstanding among African patients and their families.

  9. PCB-Based Break-Out Box

    Science.gov (United States)

    Lee, Jason H.

    2011-01-01

    Break-out boxes (BOBs) are necessary for all electrical integration/cable checkouts and troubleshooting. Because the price of a BOB is high, and no work can be done without one, often the procedure stops, simply waiting for a BOB. A less expensive BOB would take less time in the integration, testing, and troubleshooting process. The PCB-based BOB works and looks the same as a standard JPL BOB, called Gold Boxes. The only differences between the old BOB and the new PCB-based BOB is that the new one has 80 percent of its circuitry in a printed circuit board. This process reduces the time for fabrication, thus making the BOBs less expensive. Moreover, because of its unique design, the new BOBs can be easily assembled and fixed. About 80 percent of the new PCB-based BOB is in a $22 (at the time of this reporting) custom-designed, yet commercially available PCB. This device has been used successfully to verify that BOB cables were properly made. Also, upon completion, the BOB was beeped out via a multimeter to ensure that all sockets on the connectors were properly connected to the respective banana jack. When compared to the Gold Box BOBs, the new BOB has many advantages. It is much more cost efficient, it delivers equal usability at substantially lower cost of the BOB, and the Gold Box is much heavier when compared to the new BOB. The new BOB is also a bit longer and much more versatile in that connectors are easily changeable and if a banana jack is broken, it can be replaced instead of throwing away an entire BOB.

  10. Depression, pathological dependence, and risky behaviour in adolescence.

    Science.gov (United States)

    Amorosi, Marialisa; Ruggieri, F; Franchi, G; Masci, I

    2012-09-01

    During adolescence, there is an increased chance of increased incidence of depression and the development of addictive/dependent behaviours such as pathological gambling, excessive Internet use and compulsive shopping, Here we present a psychoeducational approach in the schools of Pescara and Penne to identify and treat these problems.

  11. Spontaneous symmetry breaking in a split potential box

    Science.gov (United States)

    Shamriz, Elad; Dror, Nir; Malomed, Boris A.

    2016-08-01

    We report results of an analysis of the spontaneous symmetry breaking (SSB) in a basic (actually, simplest) model that is capable of producing the SSB phenomenology in a one-dimensional setting. It is based on the Gross-Pitaevskii-nonlinear Schrödinger equation with the cubic self-attractive term and a double-well potential built as an infinitely deep potential box split by a narrow (δ functional) barrier. The barrier's strength ɛ is the single free parameter of the scaled form of the model. It may be implemented in atomic Bose-Einstein condensates and nonlinear optics. The SSB bifurcation of the symmetric ground state (g.s.) is predicted analytically in two limit cases, viz., for deep or weak splitting of the potential box by the barrier (ɛ ≫1 or ɛ ≪1 , respectively). For the generic case, a variational approximation (VA) is elaborated. The analytical findings are presented along with systematic numerical results. The stability of stationary states is studied through the calculation of eigenvalues for small perturbations and by means of direct simulations. The g.s. always undergoes the SSB bifurcation of the supercritical type, as predicted by the VA at moderate values of ɛ , although the VA fails at small ɛ , due to inapplicability of the underlying ansatz in that case. However, the latter case is correctly treated by the approximation based on a soliton ansatz. On top of the g.s., the first and second excited states are studied too. The antisymmetric mode (the first excited state) is destabilized at a critical value of its norm. The second excited state undergoes SSB bifurcation, like the g.s., but, unlike it, the bifurcation produces an unstable asymmetric mode. All unstable modes tend to spontaneously reshape into the asymmetric g.s.

  12. Searching High and Low: Prosodic Breaks Disambiguate Relative Clauses

    Science.gov (United States)

    Fromont, Lauren A.; Soto-Faraco, Salvador; Biau, Emmanuel

    2017-01-01

    During natural speech perception, listeners rely on a wide range of cues to support comprehension, from semantic context to prosodic information. There is a general consensus that prosody plays a role in syntactic parsing, but most studies focusing on ambiguous relative clauses (RC) show that prosodic cues, alone, are insufficient to reverse the preferred interpretation of sentence. These findings suggest that universally preferred structures (e.g., Late Closure principle) matter far more than prosodic cues in such cases. This study explores an alternative hypothesis: that the weak effect of prosody might be due to the influence of various syntactic, lexical-semantic, and acoustic confounding factors, and investigate the consequences of prosodic breaks while controlling these variables. We used Spanish RC sentences in three experimental conditions where the presence and position (following the first or second noun phrase) of prosodic breaks was manipulated. The results showed that the placement of a prosodic break determined sentence interpretation by changing the preferred attachment of the RC. Listeners’ natural preference for low attachment (in the absence of break) was reinforced when a prosodic break was placed after the first noun. In contrast, a prosodic break placed after the second noun reversed the preferred interpretation of the sentence, toward high attachment. We argue that, in addition to other factors, listeners indeed use prosodic breaks as robust cues to syntactic parsing during speech processing, as these cues may direct listeners toward one interpretation or another. PMID:28203214

  13. Modeling of the eddy viscosity by breaking waves

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    Breaking wave induced nearsurface turbulence has important consequences for many physical and biochemical processes including water column and nutrients mixing, heat and gases exchange across air-sea interface. The energy loss from wave breaking and the bubble plume penetration depth are estimated. As a consequence, the vertical distribution of the turbulent kinetic energy (TKE), the TKE dissipation rate and the eddy viscosity induced by wave breaking are also provided. It is indicated that model results are found to be consistent with the observational evidence that most TKE generated by wave breaking is lost within a depth of a few meters near the sea surface. High turbulence level with intensities of eddy viscosity induced by breaking is nearly four orders larger than υwl(=κu *wz), the value predicted for the wall layer scaling close to the surface, where u *w is the friction velocity in water, κ with 0.4 is the von Kármán constant, and z is the water depth, and the strength of the eddy viscosity depends both on wind speed and sea state, and decays rapidly through the depth. This leads to the conclusion that the breaking wave induced vertical mixing is mainly limited to the near surface layer, well above the classical values expected from the similarity theory. Deeper down, however, the effects of wave breaking on the vertical mixing become less important.

  14. Music Therapy with Adolescents

    Directory of Open Access Journals (Sweden)

    Jukko Tervo

    2005-03-01

    Full Text Available The therapeutic community described in this paper was situated at the University of Oulu Central Hospital Department of Psychiatry, Finland, during the years 1979-1989. The ward consisted of eight beds, four for boys and four for girls. The basic emphasis in the treatment was laid on psychoanalytic psychotherapy and music and art therapies suitable for the stage of adolescent development. Adolescent community therapy (psychoanalytic psychotherapy, music therapy, art therapy, special school etc. creates an environment which supports individual growth of the adolescent and youth culture. This, in turn, simultaneously supports psychotherapy.

  15. The role of bicultural stress and perceived context of reception in the expression of aggression and rule breaking behaviors among recent-immigrant Hispanic youth.

    Science.gov (United States)

    Forster, Myriam; Grigsby, Timothy; Soto, Daniel W; Schwartz, Seth J; Unger, Jennifer B

    2015-07-01

    Adolescent aggression and delinquency impede healthy adjustment in early adulthood and may have particularly serious long-term consequences for minority youth. Therefore, prevention research should examine these behaviors within a sociocultural framework among newer immigrant samples to determine whether, and how, adaptation to life in the US affects these behaviors. This study investigated the role of two sociocultural variables-bicultural stress and negative context of reception-on changes in aggression and rule breaking behaviors over two time points among recently immigrated Hispanic adolescents residing in Los Angeles (N = 136) and Miami-Dade (N = 142) counties. Linear stepwise regression models were used to assess the associations between predictors and behavioral outcomes. Bicultural stress and negative context of reception both had independent associations, above and beyond parental involvement and delinquent peer associations, with changes in aggressive and rule-breaking behavior during the first year of high school. These findings suggest that social, cultural, and interpersonal processes all influence deviant behaviors in recent-immigrant Hispanic populations. We discuss the implications of these finding for prevention and intervention research and practice. We also recommend that future research continue to examine the role of these factors over the course of adolescence and consider sociocultural influences when designing behavioral interventions for Hispanic immigrant populations.

  16. Facilitating Teamwork in Adolescent and Young Adult Oncology.

    Science.gov (United States)

    Johnson, Rebecca H; Macpherson, Catherine Fiona; Smith, Ashley W; Block, Rebecca G; Keyton, Joann

    2016-11-01

    A case of a young adult patient in the days immediately after a cancer diagnosis illustrates the critical importance of three interrelated core coordinating mechanisms-closed-loop communication, shared mental models, and mutual trust-of teamwork in an adolescent and young adult multidisciplinary oncology team. The case illustrates both the opportunities to increase team member coordination and the problems that can occur when coordination breaks down. A model for teamwork is presented, which highlights the relationships among these coordinating mechanisms and demonstrates how balance among them works to optimize team function and patient care. Implications for clinical practice and research suggested by the case are presented.

  17. Metastable Supersymmetry Breaking and Minimal Gauge Mediation on Branes

    CERN Document Server

    Halyo, Edi

    2010-01-01

    We construct a model with D5 branes wrapped on a deformed and resolved $A_6$ singularity which realizes metastable supersymmetry breaking and minimal gauge mediation. Supersymmetry is broken at tree level by the F--term of singlet which also obtains a VEV as required in gauge mediation. Three nodes of the singularity are used to break supersymmetry whereas the other three realize gauge mediation. The supersymmetry breaking scale is suppressed due to brane instanton effects which are computed using a geometric transition.

  18. An automatic system for elaboration of chip breaking diagrams

    DEFF Research Database (Denmark)

    Andreasen, Jan Lasson; De Chiffre, Leonardo

    1998-01-01

    A laboratory system for fully automatic elaboration of chip breaking diagrams has been developed and tested. The system is based on automatic chip breaking detection by frequency analysis of cutting forces in connection with programming of a CNC-lathe to scan different feeds, speeds and cutting...... depths. An evaluation of the system based on a total of 1671 experiments has shown that unfavourable snarled chips can be detected with 98% certainty which indeed makes the system a valuable tool in chip breakability tests. Using the system, chip breaking diagrams can be elaborated with a previously...

  19. Fermion mass generation and electroweak symmetry breaking from colour forces

    Energy Technology Data Exchange (ETDEWEB)

    Zoupanos, G. (European Organization for Nuclear Research, Geneva (Switzerland))

    1983-09-29

    The colour gauge group is extended to SU(3) x SU(3) and is subsequently broken to diagonal SU(3)sub(c). Under the diagonal SU(3)sub(c) the fundamental fermionic constituents of the larger strong group become ordinary quarks plus new quarks with exotic quantum numbers. Chiral symmetry breaking in the exotic quark sector may occur at much larger mass scales than ordinary chiral symmetry breaking, and could produce dynamical breaking of electroweak gauge symmetry and radiative masses for the light fermions.

  20. Active and break spells of the Indian summer monsoon

    Indian Academy of Sciences (India)

    M Rajeevan; Sulochana Gadgil; Jyoti Bhate

    2010-06-01

    In this paper, we suggest criteria for the identification of active and break events of the Indian summer monsoon on the basis of recently derived high resolution daily gridded rainfall dataset over India (1951–2007). Active and break events are defined as periods during the peak monsoon months of July and August, in which the normalized anomaly of the rainfall over a critical area, called the monsoon core zone exceeds 1 or is less than −1.0 respectively, provided the criterion is satisfied for at least three consecutive days. We elucidate the major features of these events. We consider very briefly the relationship of the intraseasonal fluctuations between these events and the interannual variation of the summer monsoon rainfall. We find that breaks tend to have a longer life-span than active spells. While, almost 80% of the active spells lasted 3–4 days, only 40% of the break spells were of such short duration. A small fraction (9%) of active spells and 32% of break spells lasted for a week or longer. While active events occurred almost every year, not a single break occurred in 26% of the years considered. On an average, there are 7 days of active and break events from July through August. There are no significant trends in either the days of active or break events. We have shown that there is a major difference between weak spells and long intense breaks. While weak spells are characterized by weak moist convective regimes, long intense break events have a heat trough type circulation which is similar to the circulation over the Indian subcontinent before the onset of the monsoon. The space-time evolution of the rainfall composite patterns suggests that the revival from breaks occurs primarily from northward propagations of the convective cloud zone. There are important differences between the spatial patterns of the active/break spells and those characteristic of interannual variation, particularly those associated with the link to ENSO. Hence, the

  1. Spontaneous symmetry breaking, self-trapping, and Josephson oscillations

    CERN Document Server

    2013-01-01

    This volume collects a a number of contributions on spontaneous symmetry breaking. Current studies in this general field are going ahead at a full speed. The book present review chapters which give an overview on the major break throughs of recent years. It covers a number of different physical settings which are introduced when a nonlinearity is added to the underlying symmetric problems and its strength exceeds a certain critical value. The corresponding loss of symmetry, called spontaneous symmetry breaking, alias self-trapping into asymmetric states is extensively discussed in this book.

  2. Breaking of Waves over a Steep Bottom Slope

    DEFF Research Database (Denmark)

    Jensen, Morten S.

    The thesis deals with the wave breaking process of waves propagating over a steep submerged bottom slope. The amount of energy dissipated in the wave breaking process is focused upon. An extensive number of experimental tests (>400) using regular and irregular waves breaking over a simulated reef...... in the hydraulic laboratory are performed. Based on the experimental tests several formulae developed. Formulae  are capable of predicting the transmitted wave height and wave energy flux, respectively. Futhermore, a numerical wave model based on the extended Mild-Slope equation has been developed. The model...

  3. Adolescent Egocentrism in Early and Late Adolescence.

    Science.gov (United States)

    Enright, Robert D.; And Others

    1979-01-01

    To assess adolescent egocentrism-sociocentrism, an instrument was devised to measure Elkind's constructs (the imaginary audience, the personal fable, and general self-absorption), plus nonsocial focuses and political focuses. Subjects were ten males and ten females each from three age groups: sixth-grade, eighth-grade, and college. (Author/SJL)

  4. Vitamin D deficiency in adolescents

    Directory of Open Access Journals (Sweden)

    Ashraf T Soliman

    2014-01-01

    Full Text Available The prevalence of severe vitamin D deficiency (VDD in adolescents is variable but considerably high in many countries, especially in Middle-east and Southeast Asia. Different factors attribute to this deficiency including lack of sunlight exposure due to cultural dress codes and veiling or due to pigmented skin, and less time spent outdoors, because of hot weather, and lower vitamin D intake. A potent adaptation process significantly modifies the clinical presentation and therefore clinical presentations may be subtle and go unnoticed, thus making true prevalence studies difficult. Adolescents with severe VDD may present with vague manifestations including pain in weight-bearing joints, back, thighs and/or calves, difficulty in walking and/or climbing stairs, or running and muscle cramps. Adaptation includes increased parathormone (PTH and deceased insulin-like growth factor-I (IGF-I secretion. PTH enhances the tubular reabsorption of Ca and stimulates the kidneys to produce 1, 25-(OH 2D3 that increases intestinal calcium absorption and dissolves the mineralized collagen matrix in bone, causing osteopenia and osteoporosis to provide enough Ca to prevent hypocalcaemia. Decreased insulin like growth factor-I (IGF-I delays bone growth to economize calcium consumption. Radiological changes are not uncommon and include osteoporosis/osteopenia affecting long bones as well as vertebrae and ribs, bone cysts, decalcification of the metaphysis of the long bones and pseudo fractures. In severe cases pathological fractures and deformities may occur. Vitamin D treatment of adolescents with VDD differs considerably in different studies and proved to be effective in treating all clinical, biochemical, and radiological manifestations. Different treatment regiments for VDD have been discussed and presented in this mini-review for practical use. Adequate vitamin D replacement after treating VDD, improving calcium intake (milk and dairy products, encouraging

  5. [Adolescence and choice of contraceptive].

    Science.gov (United States)

    Theunissen, L

    1986-11-01

    The majority of books, studies, and publications on adolescence are written by adults, whose frequent focus on unbridled adolescent sexuality, adolescents in crisis, or immature adolescents does not seem to correspond to the self-image of adolescents. All authors agree that adolescence is the period between childhood and adulthood beginning at puberty, but opinions differ as to the termination of adolescence and entrance into adulthood. The most significant consensus about adolescence is its tendency to become prolonged. The majority of authors regard adolescence as a preparation for adult life and hence as a natural phase necessary and indispensable to human existence. Ethnographic studies of societies that do not acknowledge adolescence demonstrate, however, that it is not a natural phase. It is also evident that comparatively few roles in modern society require lengthy periods of preparation such as adolescence. It is therefore difficult to regard adolescence as a time of preparation for adult life. From a historic perspective, adolescence emerged with the socioeconomic transformations of industrialization. Mechanization and automation excluded numerous types of workers, especially young workers, from the labor force. Adolescence represents marginalization of young people in response to socioeconomic exigencies rather than a period of preparation for a better adult life. The marginalization is internalized in the consciousness of adults and youth alike and in their hierarchical relations. The marginalization of young people is expressed in the domain of sexuality by the fact that, although physiologically mature, adolescents are not viewed as psychologically mature enough to have children. Adolescents have sexual relations at increasingly young ages, but unlike adults they are not permitted by society the choice of having a child. Contraception, an option for adults, becomes obligatory for sexually active adolescents. The refusal of contraception or failure to

  6. Individual Variation and Family-Community Ties: A Behavioral Genetic Analysis of the Intergenerational Closure in the Lives of Adolescents

    Science.gov (United States)

    Cleveland, H. Harrington; Crosnoe, Robert

    2004-01-01

    Intergenerational closure refers to parents' knowing the parents of their adolescents' friends. This study treated intergenerational closure - as reported by the parents of adolescent twins - as the dependent variable in a behavioral genetic analysis. The sample consisted of identical and fraternal twin pairs in the National Longitudinal Study of…

  7. The Treatment of Adolescent Suicide Attempters Study (TASA): Predictors of Suicidal Events in an Open Treatment Trial

    Science.gov (United States)

    Brent, David A.; Greenhill, Laurence L.; Compton, Scott; Emslie, Graham; Wells, Karen; Walkup, John T.; Vitiello, Benedetto; Bukstein, Oscar; Stanley, Barbara; Posner, Kelly; Kennard, Betsy D.; Cwik, Mary F.; Wagner, Ann; Coffey, Barbara; March, John S.; Riddle, Mark; Goldstein, Tina; Curry, John; Barnett, Shannon; Capasso, Lisa; Zelazny, Jamie; Hughes, Jennifer; Shen, Sa; Gugga, S. Sonia; Turner, J. Blake

    2009-01-01

    Objective: To identify the predictors of suicidal events and attempts in adolescent suicide attempters with depression treated in an open treatment trial. Method: Adolescents who had made a recent suicide attempt and had unipolar depression (n =124) were either randomized (n = 22) or given a choice (n = 102) among three conditions. Two…

  8. Lactose intolerance in infants, children, and adolescents.

    Science.gov (United States)

    Heyman, Melvin B

    2006-09-01

    The American Academy of Pediatrics Committee on Nutrition presents an updated review of lactose intolerance in infants, children, and adolescents. Differences between primary, secondary, congenital, and developmental lactase deficiency that may result in lactose intolerance are discussed. Children with suspected lactose intolerance can be assessed clinically by dietary lactose elimination or by tests including noninvasive hydrogen breath testing or invasive intestinal biopsy determination of lactase (and other disaccharidase) concentrations. Treatment consists of use of lactase-treated dairy products or oral lactase supplementation, limitation of lactose-containing foods, or dairy elimination. The American Academy of Pediatrics supports use of dairy foods as an important source of calcium for bone mineral health and of other nutrients that facilitate growth in children and adolescents. If dairy products are eliminated, other dietary sources of calcium or calcium supplements need to be provided.

  9. How Is Pericarditis Treated?

    Science.gov (United States)

    ... complications of pericarditis. Two serious complications are cardiac tamponade and chronic constrictive pericarditis. Cardiac tamponade is treated with a procedure called pericardiocentesis (per- ...

  10. [The pregnant adolescent].

    Science.gov (United States)

    Grenon-Plante, D

    1982-03-01

    According to the Canadian Association of Family Planning 85% of adolescents are unprotected at their 1st intercourse, and 16% become pregnant; only 20% of those having a regular sex life use contraception. Women below 20 contributed to 17% of births in 1976 in Canada; in the same year 41.5% of all new mothers were unmarried, and only 27.5% of new fathers accepted responsibility for their paternity. These figures give an idea of the extent of the problem of unwanted pregnancy among adolescents, a problem shared by all Western countries. The adolescent mother is too young to know what she wants, not to mention to accept responsibility for the caring of an infant. Risk of maternal mortality is twice as great among teenage mothers, and so is risk of infant death, mostly due to prematurity. Nurses can play a very important role in helping adolescent mothers, and they must never project their moral values on their young patients.

  11. Health counseling of adolescents.

    Science.gov (United States)

    Joffe, A; Radius, S M

    1991-05-01

    Health counseling is a fundamental aspect of health care for adolescents and is a natural extension of the concept of anticipatory guidance. It is a dynamic process involving active participation by adolescents. Pediatricians are a valued source of health-relevant information, but must also recognize how their attitudes and beliefs can affect the counseling process. Knowledge of the multitude of changes occurring during adolescence and an understanding of the role of health-risking behaviors in meeting various developmental needs are critical to successful counseling. Particular attention must be focused on ways to help adolescents develop the skills necessary to maintain health-promoting lifestyles and to resist peer pressure to engage in health-risking behaviors.

  12. Abortion in adolescence.

    Science.gov (United States)

    Greydanus, D E; Railsback, L D

    1985-09-01

    This article reviews the difficult but complex subject of abortion in adolescents. Methods of abortion are outlined and additional aspects are presented: psychological effects, counseling issues, and legal parameters. It is our conclusion that intense efforts should be aimed at education of youth about sexuality and prevention of pregnancy, utilizing appropriate contraceptive services. When confronted with a youth having an unwanted pregnancy, all legal options need to be carefully explored: delivery, adoption, or abortion. The decision belongs to the youth and important individuals in her environment. Understanding developmental aspects of adolescence will help the clinician deal with the pregnant teenagers. If abortion is selected, a first trimester procedure is best. Finally, physicians are urged to be aware of the specific, ever changing legal dynamics concerning this subject which are present in their states. Abortion is a phenomenon which has become an emotional but undeniably important aspect of adolescent sexuality and adolescent health care, in this country and around the world.

  13. Individual differences in responses to nicotine: tracking changes from adolescence to adulthood

    Institute of Scientific and Technical Information of China (English)

    Ming LI; Alexa MEAD; Rick A BEVINS

    2009-01-01

    Aim: The present study determined the extent to which individual differences in responses to the psychostimulating effect of nicotine during adolescence predict similar individual differences during adulthood in rats. We also examined the possible long-term effects of adolescent nicotine exposure on adult prepulse inhibition (PPI) of the acoustic startle response, a measure of sensorimotor gating ability.Methods: During the adolescent phase, rats were administered saline, 0.10, 0.40, or 0.60 mg/kg nicotine via subcutaneous injections for 8 days, and motor activity was measured daily. During the adult phase, these rats were treated with the same nicotine dose as in adolescence for 8 additional days. The adolescent saline rats (now adults) were subdivided into four groups and administered saline, 0.10, 0.40, or 0.60 mg/kg nicotine, respectively. PPI was assessed 12 days after the last nicotine treatment.Results: During both phases, nicotine increased motor activity across test days in a dose-dependent manner. Motor activity of rats treated with nicotine during adolescence was positively correlated with the activity recorded from the same rats during adulthood. In both phases, there were profound individual differences in the responses to the nicotine treatments. In addition, adolescent rats treated with nicotine did not show decreased motor response to the initial exposure to nicotine. Finally, adolescent exposure to nicotine at 0.4 mg/kg, but not adulthood exposure to the same dose of nicotine, produced a robust disruption of PPI, with individual rats showing different degrees of PPI disruption.Conclusion: These findings suggest that adolescent rats have increased sensitivity to the psychostimulating effect and decreased sensitivity to the aversive effect of nicotine. Also, nicotine exposure during adolescence may have long-term detrimental effects on sensorimotor gating ability.

  14. Sexting among peruvian adolescents

    OpenAIRE

    West, Joshua H.; Lister, Cameron E; Hall, P Cougar; Crookston, Benjamin T; Snow, Paola Rivera; Zvietcovich, Maria Elena; West, Richard P

    2014-01-01

    Background Sexting (sexual messaging via mobile devices) among adolescents may result in increased risky sexual practices, psychological distress and in some cases, suicide. There is very little research on sexting in developing nations, such as Peru. In particular, little is known about gender differences in the correlates of sexting. The purpose of this study was to determine the sexting prevalence and correlates of sexting among adolescent boys and girls in Cusco, Peru. Methods The study s...

  15. Adolescents sexual practices

    OpenAIRE

    Frias, Ana; Chora, Antónia

    2013-01-01

    Introduction: If teens options are experimenting sexualized practices, we should facilitate their knowledge, make them aware of their choices and help them living their sexuality in a safer mode. Objectives: To identify adolescents sexual practices; characterize the attitudes of teenagers against the use of contraception. Methods: quantitative research with exploratory nature. We studied a convenience sample of 301 adolescents of both sexes whitch attend the 9th grade. Sexual practices and a...

  16. Implants in adolescents.

    Science.gov (United States)

    Shah, Rohit A; Mitra, Dipika K; Rodrigues, Silvia V; Pathare, Pragalbha N; Podar, Rajesh S; Vijayakar, Harshad N

    2013-07-01

    Implants have gained tremendous popularity as a treatment modality for replacement of missing teeth in adults. There is extensive research present on the use of implants in adults, but there is a dearth of data available on the same in adolescents. The treatment planning and execution of implant placement in adolescents is still in its infancy. This review article is an attempt to bring together available literature.

  17. Implants in adolescents

    Directory of Open Access Journals (Sweden)

    Rohit A Shah

    2013-01-01

    Full Text Available Implants have gained tremendous popularity as a treatment modality for replacement of missing teeth in adults. There is extensive research present on the use of implants in adults, but there is a dearth of data available on the same in adolescents. The treatment planning and execution of implant placement in adolescents is still in its infancy. This review article is an attempt to bring together available literature.

  18. Adolescent fertility: worldwide concerns.

    Science.gov (United States)

    Senderowitz, J; Paxman, J M

    1985-04-01

    There is growing concern over the adverse health, social, economic, and demographic effects of adolescent fertility. Morbidity and mortality rates ar significantly higher for teenage mothers and their infants, and early initiation of childbearing generally means truncated education, lower future family income, and larger completed family size. Adolescent fertility rates, which largely reflect marriage patterns, range from 4/1000 in Mauritania; in sub-Saharan Africa, virtually all rates are over 100. In most countries, adolescent fertility rates are declining due to rising age at marriage, increased educational and economic opportunities for young women, changes in social customs, increased use of contraception, and access to abortion. However, even if fertility rates were to decline dramatically among adolescent women in developing countries, their sheer numbers imply that their fertility will have a major impact on world population growth in the years ahead. The number of women in the world ages 15-19 years is expected to increase from 245 million in 1985 to over 320 million in the years 2020; 82% of these women live in developing countries. As a result of more and earlier premarital sexual activity, fostered by the lengthening gap between puberty and marriage, diminished parental and social controls, and increasing peer and media pressure to be sexually active, abortion and out-of-wedlock childbearing are increasing among teenagers in many developed and rapidly urbanizing developing countries. Laws and policies regarding sex education in the schools and access to family planning services by adolescents can either inhibit or support efforts to reduce adolescent fertility. Since contraceptive use is often sporadic and ineffective among adolescents, family planning services are crucial. Such programs should aim to reduce adolescents' dependence on abortion through preventive measures and increase awareness of the benefits of delayed sexual activity. Similarly, sex

  19. Catalysis of Dynamical Chiral Symmetry Breaking by Chiral Chemical Potential

    CERN Document Server

    Braguta, V V

    2016-01-01

    In this paper we study the properties of media with chiral imbalance parameterized by chiral chemical potential. It is shown that depending on the strength of interaction between constituents in the media the chiral chemical potential either creates or enhances dynamical chiral symmetry breaking. Thus the chiral chemical potential plays a role of the catalyst of dynamical chiral symmetry breaking. Physically this effect results from the appearance of the Fermi surface and additional fermion states on this surface which take part in dynamical chiral symmetry breaking. An interesting conclusion which can be drawn is that at sufficiently small temperature chiral plasma is unstable with respect to condensation of Cooper pairs and dynamical chiral symmetry breaking even for vanishingly small interactions between constituents.

  20. Parking Areas at Cedar Breaks National Monument, Utah (prkareas)

    Data.gov (United States)

    National Park Service, Department of the Interior — This polygon dataset locates the parking areas within Cedar Breaks National Monument. The parking areas were digitized from the 2002 Color aerial photographs and the...