WorldWideScience

Sample records for breaks treating adolescents

  1. When the Levee Breaks: Treating Adolescents and Families in the Aftermath of Hurricane Katrina

    Science.gov (United States)

    Rowe, Cynthia L.; Liddle, Howard A.

    2008-01-01

    Hurricane Katrina brought to the surface serious questions about the capacity of the public health system to respond to community-wide disaster. The storm and its aftermath severed developmentally protective family and community ties; thus its consequences are expected to be particularly acute for vulnerable adolescents. Research confirms that…

  2. WHEN THE LEVEE BREAKS: TREATING ADOLESCENTS AND FAMILIES IN THE AFTERMATH OF HURRICANE KATRINA

    OpenAIRE

    Rowe, Cynthia L.; Liddle, Howard A.

    2008-01-01

    Hurricane Katrina brought to the surface serious questions about the capacity of the public health system to respond to community-wide disaster. The storm and its aftermath severed developmentally protective family and community ties; thus its consequences are expected to be particularly acute for vulnerable adolescents. Research confirms that teens are at risk for a range of negative outcomes under conditions of life stress and family disorganization. Specifically, the multiple interacting r...

  3. Treating Children and Adolescents

    Science.gov (United States)

    ... dosages also must be tailored, based upon the child's weight. Children and adolescents are moving through a period of physical and emotional growth and development. Special consideration must be given to potential side ...

  4. Treating Adolescents for Substance Abuse and Comorbid Psychiatric Disorders

    OpenAIRE

    Riggs, Paula D.

    2003-01-01

    Recent research has identified a cluster of standardized approaches that effectively treat adolescents with substance abuse disorders. Many of these approaches share elements that may be adopted to improve outcomes in substance treatment programs. In adolescents, treatment goals should be informed by a comprehensive assessment that includes the adolescent patient’s developmental history and evaluation of psychiatric comorbidity. Treatment for behavioral, psychosocial, and psychiatric problems...

  5. Preventing and Treating Substance Abuse among Adolescents

    Science.gov (United States)

    Sussman, Steve

    2011-01-01

    Substance misuse is one of the most prevalent causes of adolescent injury and death. Additionally, 5-8% of adolescents in the U.S. qualify for a diagnosis of substance abuse disorder. This article discusses formal prevention and treatment program models, focusing on a continuum of care which extends from prevention to treatment alternatives.…

  6. Chromosomal break points in irradiated and ethyl methane sulphonate treated leucocytes of patients with Down syndrome

    International Nuclear Information System (INIS)

    Frequencies of chromosomal damage in the peripheral leucocytes of patients with Down syndrome, on exposure to gamma rays (2Gy) or ethyl methane sulphonate (EMS, 1 x 10-4M), were assessed. Analysis of break points in the chromosomes of irradiated cells revealed a non-random occurrence. Six of the break points observed in EMS-treated cells were found to overlap with those recorded in irradiated cells. Thirteen break points observed were found to correlate with the location of cancer-specific break points and four of these coincided with the bands where oncogenes have been located. Two break points were localised to the same bands as that of known heritable fragile sites. (author). 17 refs., 2 figs., 3 tabs

  7. Tobacco control for clinicians who treat adolescents.

    Science.gov (United States)

    Sargent, James D; DiFranza, Joseph R

    2003-01-01

    Smoking remains the most common preventable cause of death in the developed world, and is rapidly becoming an important cause of death in the developing world. Nicotine is a powerfully addictive substance, and the tobacco industry spends billions annually promoting it in the United States. It is therefore important for clinicians to understand why people smoke, to address smoking in patients of all ages, and to lobby for health-preserving tobacco control policies at the community level. Children take up smoking in response to social influences: smoking by friends, parents, and family, and through exposure to smoking in media. Parents who smoke not only model the behavior, but also often make the product available by leaving cigarettes around the house. Media influences include the dollar 10 billion spent per year on tobacco marketing, but more importantly, the modeling of the behavior on screen by movie and television stars. Once children start smoking, many rapidly lose autonomy over the behavior. Youth can get hooked after smoking just a few cigarettes. The most effective community efforts for reducing tobacco use are: raising the price of tobacco; halting the sale of tobacco to minors; enforcing strict school tobacco policies; and making public places smoke free through local ordinances. Working with individuals, clinicians should support cessation in all smokers, including parents of children and adolescents. They should screen children for smoking risk factors beginning at age 10. They should teach parents to maintain smoke-free households, to set nonsmoking expectations early on, and to monitor adolescents for signs of smoking. Parents should limit exposure to adult media (e.g., R-rated movies) and use family television time to discuss the effect of seeing screen depictions of smoking on adolescent behavior. Adolescents who smoke should be assessed for signs of nicotine dependence and counseled about quitting. Clinicians are effective community voices; they

  8. Treating depression in children and adolescents: what options now?

    Science.gov (United States)

    Varley, Christopher K

    2006-01-01

    There have been significant developments in the understanding of depression in children and adolescents in the past few years, including an increased recognition that significant depressive illness occurs in this patient group. Pharmacological and psychotherapeutic treatments are used to manage depression in children and adolescents, and there is evidence from randomised, double-blind, placebo-controlled trials of benefit for both approaches. However, not all medication trials have been positive. In addition, there have been increasing concerns about specific safety issues related to the use of medications to treat depression, with an overall finding of mood-related adverse effects, including suicide attempts, in 4% of active drug versus 2% of placebo recipients in controlled trials involving children and adolescents. This has resulted in regulatory actions in a number of countries that have ranged from the declaration of contraindication for most antidepressants (in Great Britain), to relegation of antidepressants to a second-line intervention (in New Zealand) to a Black Box warning (in the US). It can be concluded that best practice combines treatment with both medication and psychotherapy, and that important safety issues must be monitored carefully when children and adolescents are treated for depression. On balance, there appears to be evidence of the benefit for antidepressant medications in children and adolescents, which outweigh safety concerns. PMID:16396520

  9. Developmental pathways from childhood aggression-disruptiveness, chronic peer rejection, and deviant friendships to early-adolescent rule breaking.

    Science.gov (United States)

    Ettekal, Idean; Ladd, Gary W

    2015-01-01

    Childhood aggression-disruptiveness (AD), chronic peer rejection, and deviant friendships were examined as predictors of early-adolescent rule-breaking behaviors. Using a sample of 383 children (193 girls and 190 boys) who were followed from ages 6 to 14, peer rejection trajectories were identified and incorporated into a series of alternative models to assess how chronic peer rejection and deviant friendships mediate the association between stable childhood AD and early-adolescent rule breaking. There were multiple mediated pathways to rule breaking that included both behavioral and relational risk factors, and findings were consistent for boys and girls. Results have implications for better understanding the influence of multiple social processes in the continuity of antisocial behaviors from middle childhood to early adolescence. PMID:25403544

  10. Parents‘ and peers‘ influence on norms and norm-breaking behavior of Slovak adolescent boys and girls

    Czech Academy of Sciences Publication Activity Database

    Ruiselová, Z.; Urbánek, Tomáš

    2008-01-01

    Roč. 50, č. 2 (2008), s. 191-200. ISSN 0039-3320 Institutional research plan: CEZ:AV0Z70250504 Keywords : adolescents * norm-breaking behavior * structural equations model Subject RIV: AN - Psychology Impact factor: 0.258, year: 2008

  11. Adolescent idiopathic scoliosis: Retrospective analysis of 235 surgically treated cases

    Directory of Open Access Journals (Sweden)

    Unnikrishnan Ranjith

    2010-01-01

    Full Text Available Background : The surgical treatment of adolescent idiopathic scoliosis (AIS has taken great strides in the last two decades. There have been no long term reported studies on AIS from India with documented long term followup. In this study we review a single surgical team′s series of 235 surgically treated cases of AIS with a follow-up from two to six years. Materials and Methods : Pre operative charts, radiographs and MRI scans for 235 patients were collected for this study. The patients were grouped into three groups where anterior correction and fusion (n=47, posterior correction and fusion (n=123 and combined anterior release and posterior instrumentation (n=65 was performed. Each group was divided into two subgroups based on the surgical approach and instrumentation strategy (all screw construct or hybrid construct used. Patients were followed up for coronal and saggital plane corrections, apical vertebral translation (AVT, trunk balance and back pain. The percentage of correction was calculated in each group as well as sub groups. Results : The incidence of MRI detected intraspinal anomaly in this series is 5.9% with 3.4% of them requiring neurosurgical procedure along with scoliosis correction. Average coronal major curve correction was 66% in the all screw group and 58.5% in the hybrid group. The coronal plane correction was better when the all screw constructs were employed. Also, the AVT and trunk balance was better with the all screw constructs. The anterior corrections resulted in better correction of the AVT and trunk balance as compared to the posterior correction. There were eight (3.4% complications in this series. The coronal and saggital plane correction paralleled the published international standards. Conclusion : The coronal plane correction was better when all screw constructs were employed. Use of all pedicle screw systems obviated the need for costoplasty in most cases. The increased incidence of intraspinal anomaly may

  12. Developmental Pathways from Childhood Aggression-Disruptiveness, Chronic Peer Rejection and Deviant Friendships to Early-Adolescent Rule Breaking

    OpenAIRE

    Ettekal, Idean; Ladd, Gary W.

    2014-01-01

    Childhood aggression-disruptiveness, chronic peer rejection, and deviant friendships were examined as predictors of early-adolescent rule breaking behaviors. Using a sample of 383 children (193 girls and 190 boys) who were followed from ages 6 to 14, peer rejection trajectories were identified and incorporated into a series of alternative models to assess how chronic peer rejection and deviant friendships mediate the association between stable childhood aggression-disruptiveness and early-ado...

  13. A model treating the DNA double-strand break repair inhibition by damage clustering

    International Nuclear Information System (INIS)

    A microdosimetric model for the interpretation of radiation induced irreparable DNA double-strand breaks was applied to the biological endpoint of chromosomal aberrations. The model explains irreparable DNA double-strand breaks in terms of break clustering in DNA subunits. The model predicts quite good chromosomal aberrations in gamma- and X-ray irradiated V79 cells and human lymphocytes. In the case of α-particle irradiation the presumption had to be made, that only the cells with indirect events in the nucleus (due to delta-electrons) reach the metaphase and are analysed. With the help of this model we are able to explain the peculiar effectiveness of ultrasoft C-X-rays in human lymphocytes. In addition, an interpretation of experiments with accelerated and spatially correlated particles is given. (author)

  14. Transactional Links Between Teacher-Student Relationships and Adolescent Rule-Breaking Behavior and Behavioral School Engagement: Moderating Role of a Dopaminergic Genetic Profile Score.

    Science.gov (United States)

    De Laet, Steven; Colpin, Hilde; Van Leeuwen, Karla; Van den Noortgate, Wim; Claes, Stephan; Janssens, Annelies; Goossens, Luc; Verschueren, Karine

    2016-06-01

    Throughout adolescence, there is an increase in rule-breaking behavior and a decrease in behavioral school engagement. The role of teacher-student relationship quality in the development of these adjustment problems remains understudied. This study examined how adolescent-reported teacher-student affiliation and dissatisfaction and parent-reported rule-breaking behavior and behavioral engagement impact one another throughout adolescence. In addition, we examined the moderating effect of genes by means of a Biologically Informed Multilocus genetic Profile Score (BIMPS), a composite score reflecting the cumulative effect of multiple dopaminergic genes, with a higher score indicating higher dopamine signaling in the adolescent brain. We used three-year longitudinal data from 1111 adolescents (51 % boys; M age = 13.79), and their parents. Cross-lagged analyses revealed a transactional process in which adolescents who display more rule-breaking behavior and less behavioral engagement experienced increased subsequent dissatisfaction with their teachers, which in turn further increased their adjustment problems. Also, adolescents with more adjustment problems experienced decreased subsequent affiliation with their teachers. The other way around, adolescents' behavioral engagement also benefitted from positive relationships with teachers. Multi-group analyses revealed genetic moderation for behavioral engagement, but not for rule-breaking. Specifically, adolescents who had a BIMPS score coding for moderate levels of dopamine signaling (instead of high or low signaling) were most affected in their behavioral engagement when they experienced dissatisfaction with their teachers. Our study findings may guide schools in implementing interventions to create a supportive class and school environment including positive, supportive teacher-student relationships and indicate that providing a such a supportive school environment is important for all adolescents. PMID:27013478

  15. Treating Social Anxiety in Adolescents: Ten Group Therapy Lesson Plans

    Science.gov (United States)

    Mazur-Elmer, Alison; McBride, Dawn

    2009-01-01

    This project provides a comprehensive overview of the research literature on social anxiety disorder (SAD) in adolescents and concludes by offering a set of 10 group therapy lesson plans for SAD that therapists can use in their practice. The overview includes a description of social anxiety disorder and highlights various theories of anxiety. The…

  16. An Investigation of Successfully Treated Adolescent Sex Offenders

    Science.gov (United States)

    Franey, Kristina Crumpton; Viglione, Donald J.; Wayson, Peter; Clipson, Clark; Brager, Robert

    2004-01-01

    Little is known about the characteristics of adolescent sex offenders who do not reoffend. Most studies emphasize reoffense rates, recidivism and those who reoffend. Moreover, these studies provide quantitative summaries without describing the individual, his behavior, and challenges after treatment. The present study seeks to provide novel…

  17. Cognitive outcome in children and adolescents treated for acute lymphoblastic leukaemia with chemotherapy only

    OpenAIRE

    Lofstad, G Elisabeth; Reinfjell, Trude; Hestad, Knut; Diseth, Trond H

    2009-01-01

    Objective: To examine cognitive outcome in children and adolescents with acute lymphoblastic leukaemia (ALL) in remission, treated with central nervous system prophylactic chemotherapy only. Method: Thirty-five children and adolescents, age 8.4–15.3 years in long-term remission from ALL, 4.2–12.4 years post diagnosis, without relapse and no prediagnosis history of neurodevelopmental disorder were compared with 35 healthy controls matched for gender and age, on measures of intellectual functio...

  18. [Psychosocial Characteristics of Adolescents Treated for Alcohol Intoxication in Emergency Departments].

    Science.gov (United States)

    Wartberg, Lutz; Diestelkamp, Silke; Arnaud, Nicolas; Thomasius, Rainer

    2016-09-01

    Psychosocial Characteristics of Adolescents Treated for Alcohol Intoxication in Emergency Departments In Germany, every year a substantial number of adolescents is treated in emergency departments for acute alcohol intoxication. Until now, only few studies have been published investigating psychosocial aspects in this group of adolescents. In the present study 316 adolescents were surveyed in the emergency department regarding their problematic use of alcohol and illicit drugs, their patterns of alcohol consumption, their alcohol-related and mental problems. We reported results for the whole sample. Additionally, the sample was divided in two groups based on the result in an established screening instrument for problematic alcohol use (CRAFFT-d). To compare the two groups we conducted unpaired t tests, chi-square tests and logistic regression analyses. Compared to the other group the adolescents exceeding the cut-off value of the CRAFFT-d reported a statistically significant higher past 30-day binge drinking frequency and number of standard-drinks consumed on a typical drinking occasion, more alcohol-related problems, more frequently a problematic use of illicit drugs and more mental problems (regarding antisocial behavior, anger control problems and self-esteem). Antisocial behavior was the most important factor for the affiliation to one of the two groups. The application of the screening instrument for problematic alcohol use (CRAFFT-d) in the emergency department seems to be a promising approach to identify adolescents with a general higher psychosocial burden. PMID:27595810

  19. Breaking the Taboo: Illicit Drug Use among Adolescents with Type 1 Diabetes Mellitus

    Directory of Open Access Journals (Sweden)

    Anna M. Hogendorf

    2016-01-01

    Full Text Available Background. The aim of the study was to explore the prevalence of illicit drug use in a group of Polish adolescents with type 1 diabetes (DM1 in comparison with a national cohort of their healthy peers. Methods. Two hundred and nine adolescents with DM1, aged 15–18 years, were studied in 2013 with an anonymous questionnaire prepared for the European School Survey Project on Alcohol and Other Drugs (ESPAD. The control group was a representative sample of 12114 students at the same age who took part in ESPAD in 2011. Metabolic control was regarded as good if self-reported HbA1c was <8% or poor if HbA1c was ≥8%. Results. Lifetime prevalence of illicit drug use was lower among adolescents with DM1 than in the control group [58 (28% versus 5524 (46%, p=10-5]. Cannabis preparations were the most frequently used substances [38 (18.3% versus 3976 (33.1%, p=10-5], followed by tranquilizers, sedatives, and amphetamine. Lifetime and last 12-month use of cannabis were associated with poorer glycemic control (HbA1c ≥ 8%, p<0.01 and 0.02, respectively. Conclusions. Adolescents with DM1 report using illicit drugs to a lesser extent than their healthy peers. The use of cannabis is associated with a poorer metabolic control in teens with DM1.

  20. Influence of mea on dna breaks accumulation in bac. stearothermophilus exposed to γ- and UV-radiation and treated with nitrosomethylurea

    International Nuclear Information System (INIS)

    β-Mercaptoethylamine (MEA) decreased the accumulation of enzymatic single- and double-strand breaks in DNA of thermophilic bacteria exposed to γ- and UV- radiation and treated with N-nitroso-N-methylurea. The protective effect of MEA, as registered according to accumulation of single-strand and double-strand breaks in DNA of Bac. stearothermophilus immediately after irradiation and after 30 min postirradiation incubation, was similar

  1. Evaluation of the Immediate Dentofacial Changes in Late Adolescent Patients Treated with the Forsus™ FRD

    OpenAIRE

    Gunay, Esen Ali; Arun, Tulin; Nalbantgil, Didem

    2011-01-01

    Objectives: The purpose of this study was to evaluate the short-term dentoalveolar and soft tissue changes in late adolescent patients treated with the Forsus™ FRD. Methods: A prospective study was carried out on 54 lateral cephalometric radiograms that were taken before placement and after removal of the appliance in the treatment group (15 subjects) and at the beginning and six months after in the control group (12 subjects). The patient selection criteria were as follows: skeletal and dent...

  2. Children and adolescents previously treated with glucocorticoids display lower verbal intellectual abilities

    DEFF Research Database (Denmark)

    Holm, Sara Krøis; Vestergaard, Martin; Madsen, Kathrine Skak;

    2015-01-01

    AIM: Perinatal exposure to glucocorticoids has been associated with adverse cerebral effects, but little is known about their effect on cognitive development and exposure later in childhood. This study examined intellectual abilities, memory and behavioural problems in children previously treated...... equivalents was 158 mg/kg (range 21-723) and the mean time that had elapsed since treatment was three-and-a-half (standard deviation 2.2) years. Intellectual abilities were assessed with the Wechsler Intelligence Scale for Children and memory performance and behavioural problems with a pattern recognition...... disease groups. There were no significant dose-response relationships regarding verbal intellectual abilities. CONCLUSION: Children and adolescents previously treated with glucocorticoids seemed to have lower intellectual verbal abilities than healthy controls....

  3. Hyperprolactinemia in Thai children and adolescents with autism spectrum disorder treated with risperidone

    Science.gov (United States)

    Hongkaew, Yaowaluck; Ngamsamut, Nattawat; Puangpetch, Apichaya; Vanwong, Natchaya; Srisawasdi, Pornpen; Chamnanphon, Montri; Chamkrachchangpada, Bhunnada; Tan-kam, Teerarat; Limsila, Penkhae; Sukasem, Chonlaphat

    2015-01-01

    Hyperprolactinemia is a common adverse effect observed in children with autism spectrum disorder (ASD) during pharmacotherapy with risperidone. The main aim of this study was to investigate important clinical factors influencing the prolactin response in risperidone-treated Thai ASD. A total of 147 children and adolescents (127 males and 20 females) aged 3–19 years with ASD received risperidone treatment (0.10–6.00 mg/day) for up to 158 weeks. Prolactin levels were measured by chemiluminescence immunoassay. The clinical data of patients collected from medical records – age, weight, height, body mass index, dose of risperidone, duration of treatment, and drug-use pattern – were recorded. Hyperprolactinemia was observed in 66 of 147 (44.90%) subjects. Median prolactin level at the high doses (24.00, interquartile range [IQR] 14.30–29.20) of risperidone was significantly found to be higher than at the recommended (16.20, IQR 10.65–22.30) and low (11.70, IQR 7.51–16.50) doses of risperidone. There was no relationship between prolactin levels and duration of risperidone treatment. Dose-dependence is identified as a main factor associated with hyperprolactinemia in Thai children and adolescents with ASD treated with risperidone. This study suggests that risperidone treatment causes prolactin elevations and the effects of risperidone on prolactin are probably dose-related in pediatric patients. PMID:25653528

  4. Hyperprolactinemia in Thai children and adolescents with autism spectrum disorder treated with risperidone

    Directory of Open Access Journals (Sweden)

    Hongkaew Y

    2015-01-01

    Full Text Available Yaowaluck Hongkaew,1,2 Nattawat Ngamsamut,3 Apichaya Puangpetch,1,2 Natchaya Vanwong,1,2 Pornpen Srisawasdi,4 Montri Chamnanphon,1,2 Bhunnada Chamkrachchangpada,3 Teerarat Tan-kam,3 Penkhae Limsila,3 Chonlaphat Sukasem1,2 1Division of Pharmacogenomics and Personalized Medicine, Department of Pathology, Faculty of Medicine, 2Laboratory for Pharmacogenomics, Somdech Phra Debaratana Medical Center (SDMC, Ramathibodi Hospital, Mahidol University, 3Yuwaprasart Waithayopathum Child and Adolescent Psychiatric Hospital, Department of Mental Health Services, Ministry of Public Health, 4Division of Clinical Chemistry, Department of Pathology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand Abstract: Hyperprolactinemia is a common adverse effect observed in children with autism spectrum disorder (ASD during pharmacotherapy with risperidone. The main aim of this study was to investigate important clinical factors influencing the prolactin response in risperidone-treated Thai ASD. A total of 147 children and adolescents (127 males and 20 females aged 3–19 years with ASD received risperidone treatment (0.10–6.00 mg/day for up to 158 weeks. Prolactin levels were measured by chemiluminescence immunoassay. The clinical data of patients collected from medical records – age, weight, height, body mass index, dose of risperidone, duration of treatment, and drug-use pattern – were recorded. Hyperprolactinemia was observed in 66 of 147 (44.90% subjects. Median prolactin level at the high doses (24.00, interquartile range [IQR] 14.30–29.20 of risperidone was significantly found to be higher than at the recommended (16.20, IQR 10.65–22.30 and low (11.70, IQR 7.51–16.50 doses of risperidone. There was no relationship between prolactin levels and duration of risperidone treatment. Dose-dependence is identified as a main factor associated with hyperprolactinemia in Thai children and adolescents with ASD treated with

  5. Subsequent fertility and birth histories of children and adolescents treated with 131I for thyroid cancer

    International Nuclear Information System (INIS)

    Forty patients aged 20 years or less who had been treated with 131I after surgery for papillary-follicular thyroid carcinoma were contacted for followup study. Five had died and two were unmarried; the remaining 33 were studied with respect to their subsequent reproductive histories and the health of the offspring. The mean age at the time of the first 131I therapeutic dose was 14.6 years (range 6 to 20), and the average followup interval, from that first dose until followup, was 18.7 years (range 14 to 25). The mean total dose of 131I was 196 mCi (range 80 to 691). The incidences of infertility (12 percent), miscarriage (1.4 percent), prematurity (8 percent), and major congenital anomaly (1.4 percent) found in this series are not significantly different from those in the general population. Thus, our study offers no overt evidence of genetic damage in children and adolescents treated with high doses of 131I for thyroid carcinoma

  6. Tratamento de macroprolactinoma com cabergolina em adolescente An adolescent patient with prolactinoma treated with cabergoline

    Directory of Open Access Journals (Sweden)

    Leila Warszawski

    2011-09-01

    Full Text Available OBJETIVO: Relatar um caso de macroprolactinoma diagnosticado em adolescente e tratado com cabergolina. DESCRIÇÃO DO CASO: Paciente do sexo feminino, 15 anos, iniciou quadro clínico aos dez anos, com cefaleia, obesidade e não havia apresentado menarca ao diagnóstico. A dosagem sérica inicial de prolactina foi de 2492ng/mL (valor de referência: 19-25ng/mL. A ressonância nuclear magnética de crânio evidenciou formação expansiva selar e suprasselar compatível com macroadenoma hipofisário sem compressão do quiasma óptico. Seis meses após o início do tratamento com cabergolina, houve queda significativa dos níveis séricos de prolactina para 87,7ng/mL, com redução de 76% no tamanho da lesão e melhora sintomática. COMENTÁRIOS: A ocorrência dos prolactinomas é rara na infância e na adolescência, mas o seu comportamento pode ser mais agressivo. O diagnóstico precoce e o manejo adequado do caso são importantes para um bom prognóstico.OBJECTIVE: To report a teenager with macroprolactinoma treated with cabergoline. CASE DESCRIPTION: A 15-year old female adolescent reported the onset of headaches and obesity since ten years old. At diagnosis amenorrhea was not present. The serum level of prolactin was initially 2492ng/mL (reference values: 19-25ng/mL. Magnetic resonance images of the skull revealed an expansive sellar and suprasellar pituitary macroadenoma without optical chiasmal compression. Six months after starting treatment with cabergoline, there was a significant decrease of prolactin levels to 87.7 ng/mL, with a 76% reduction in the lesion size and she reported improvement of the symptoms. COMMENTS: In childhood and adolescence, prolactinomas are rare, but when they occur the clinical course is more aggressive. Early diagnosis and proper management of the disease are important for a good prognosis.

  7. Clinical Case Rounds in Child and Adolescent Psychiatry: Enuresis and ADHD in Older Children and an Adolescent Treated with Stimulant Medication: A Case Series

    OpenAIRE

    Williamson, Lloyda B.; Gower, Michael; Ulzen, Thaddeus

    2011-01-01

    Uncommonly, older children and adolescents can present with a history of enuresis. Resolution of enuresis followed the diagnosis and treatment of Attention Deficit Hyperactivity Disorder (ADHD) in each child in this case series. Subjects were three children with DSM-IV-TR ADHD, who presented with a history of primary nocturnal enuresis (PNE). Our results reveal that a subgroup of children with ADHD plus enuresis, when treated with stimulant medication, demonstrated resolution of enuresis as w...

  8. Risperidone induces long-lasting changes in the conditioned avoidance response and accumbal gene expression selectively in animals treated as adolescents.

    Science.gov (United States)

    Moe, Aung Aung Kywe; Kurniawan, Nyoman D; Alexander, Suzanne; Cui, Xiaoying; Burne, Thomas H J; Eyles, Darryl W

    2016-09-01

    Adolescence is a period of dynamic remodeling and maturation in the brain. Exposure to psychotropic drugs during adolescence can potentially alter neural maturation in the adolescent brain subsequently altering neural function at maturity. In this regard, antipsychotic drugs (APDs) are important given a notable global increase in prescription of these APDs to adolescents for a variety of behavioural symptoms and conditions over the past twenty years. However, there is a paucity of data on the long-term consequences of APDs on the adolescent brain. In this preclinical study, we have examined whether the adolescent brain is more susceptible than the adult brain to long-term neural changes induced by risperidone, which is the APD most frequently prescribed to adolescents. Rats were chronically treated (21 days) with 1.3 mg/kg/day risperidone or vehicle either as adolescents (postnatal day (PND) 36-56)) or adults (PND80-100). Behaviour was assessed using the well-described suppression of the conditioned avoidance response (CAR) by APDs. We examined CAR after all animals had reached maturity (PND127). We show that mature rats treated with risperidone as adolescents had increased CAR suppression compared to adults when rechallenged with this same drug. In the nucleus accumbens, significant downregulation of serotonergic 5HT2A receptors and catechol-o-methyl transferase mRNA levels was observed only in the adolescent treated animals. Impaired 5HT2A receptor signaling may explain the increased CAR suppression observed in rats treated with risperidone as adolescents. Magnetic resonance imaging (MRI), however, did not detect any risperidone-induced long-term brain structural change at maturity. These findings confirm that APD administration during adolescence may produce long-term behavioural and neurochemical alterations. PMID:27130903

  9. Cognitive–Behavioral Therapy and Hypnotic Relaxation to Treat Sleep Problems in an Adolescent With Diabetes

    OpenAIRE

    Perfect, Michelle M.; Elkins, Gary R.

    2010-01-01

    Inadequate sleep among adolescents frequently contributes to obesity and reduced academic performance, along with symptoms of anxiety, depression, fatigue, and attention deficits. The etiological bases of sleep quality has been associated with both stress and sleep habits. These problems tend to be especially important for adolescents with diabetes as the effects of poor sleep complicate health outcomes. This case example concerns a 14-year-old adolescent girl with a history of type I diabete...

  10. Testing the Effects of Peer Socialization versus Selection on Alcohol and Marijuana Use among Treated Adolescents

    OpenAIRE

    Becker, Sara J.; Curry, John F.

    2013-01-01

    This study examined the relative influence of peer socialization and selection on alcohol and marijuana use among 106 adolescents who received a brief intervention. Adolescents were recruited between 2003 and 2007 and followed for 12 months as part of a SAMHSA-funded study. Cross-lagged panel models using four assessment points examined the longitudinal relationship between adolescent substance use and peer substance involvement separately for alcohol and marijuana. Consistent with community ...

  11. Body composition changes during interventions to treat overweight and obesity in children and adolescents: a descriptive review

    OpenAIRE

    Pilar de Miguel-Etayo; Moreno, Luis A; Iris Iglesia; Silvia Bel-Serrat; Theodora Mouratidou; Garagorri, Jesús M.

    2013-01-01

    Nutrition, physical activity and behavior-modifying techniques are widely applied components of interventions treating obesity. Our aim was to review available information on the short and long term effects of intervention treatment on body fat composition of overweight and obese children and adolescents and, to obtain a further understanding on how different body composition techniques detect longitudinal changes. In total, thirteen papers were included; seven included a multidisciplinary in...

  12. Breaking Away to Find a Way: Poverty and School Failure in a Spanish Adolescent Life-History

    Science.gov (United States)

    Calderon-Almendros, I.

    2011-01-01

    This article is part of a biographical research study, and explores the social path that an adolescent from a marginal background in Malaga (Spain) has travelled throughout his life. The research shows a class differentiation that divides society in two: you, who control the means of production, impose your culture, and define the policy and the…

  13. Treating Adolescents with Social Anxiety Disorder in School: An Attention Control Trial

    Science.gov (United States)

    Warner, Carrie Masia; Fisher, Paige H.; Shrout, Patrick E.; Rathor, Snigdha; Klein, Rachel G.

    2007-01-01

    Background: Anxiety disorders are often undetected and untreated in adolescents. This study evaluates the relative efficacy of a school-based, cognitive-behavioral intervention compared to an educational-supportive treatment for adolescents with social anxiety disorder. Methods: Thirty-six students (30 females), ages 14 to 16, were randomized to a…

  14. Self-determined motivation towards physical activity in adolescents treated for obesity: an observational study

    Directory of Open Access Journals (Sweden)

    Theuwis Lotte

    2011-09-01

    Full Text Available Abstract Background Within the Self-Determination Theory (SDT framework, the first major study aim was to investigate the SDT tenets in an obese adolescent population by examining the factor structure of the Behavioural Regulation in Exercise Questionnaire-2 (BREQ-2 and by investigating associations between physical activity (PA and motivation in obese adolescents. The second aim was to study differences in motivation according to adolescents' educational level, since lower educated obese adolescent are a sub-risk group for lower PA levels among the obese adolescents. The third aim was to investigate whether attending a residential obesity treatment program could lead to an increase in autonomous motivation towards PA and to see if the treatment effect on motivation was different in low versus high educated youth. Methods For the first study aim, the sample comprised 177 obese adolescents at the start of a 10-month multidisciplinary residential obesity treatment program (BMI = 35.9 ± 6.0 kg/m2, 15.1 ± 1.5 years, 62% girls. A subsample of 65 adolescents (stratified by educational level were divided into low (n = 34 versus high educated (n = 31 as part of the second and third study aim. Motivation was assessed using the BREQ-2 and PA using the Flemish Physical Activity Questionnaire. Results Exploratory factor analysis showed sufficient validations with the original factor for 17 out of 19 BREQ-2 items. Significant positive correlations were found between PA and the composite score of relative autonomy (r = 0.31, p Conclusions The BREQ-2 can be used in an obese adolescent population. Higher levels of autonomous motivation towards PA were related to higher PA levels. Adolescents had increases in both autonomous and controlled forms of motivation during treatment. Special attention for lower educated adolescents during treatment is needed, as they have a lower autonomous motivation at the start of treatment and an increase in introjected

  15. Can the provision of games equipment at school break time increase the physical activity levels of adolescents?

    OpenAIRE

    Carter, Alice; Evans, Adam

    2013-01-01

    The promotion of physical activity to young people is currently a public health priority due to growing concerns that this group is not sufficiently physically active. Adolescence in particular is characterised with a decline in physical activity levels (Verstraete, et al 2006, Journal of Public Health, 16: 415-419). There exists an increased concern that Physical Education lessons within the National School Curriculum do not assist with this downward trend in activity levels, thus the notion...

  16. Self-Esteem in Children and Adolescents Differently Treated for Locomotory Trauma

    OpenAIRE

    Jonovska, Suzana; Frančišković, Tanja; Kvesić, Ante; Nikolić, Hary; Brekalo, Zrinko; Pavlović, Eduard; Dalija Bilić, Daliborka

    2007-01-01

    Self-esteem involves the evaluative and affective dimensions of self-concept. It could be influenced by stress situations such as diseases or injuries, especially in the period of puberty and adolescence. The aim of this study was to establish the influence of isolated long tubular bone limbs’ fractures in children and adolescents and type of its treatment (conservative or active surgical treatment-various techniques) on self-esteem of patients, as well as to establish relationships ...

  17. Treatment resistant adolescent depression with upper airway resistance syndrome treated with rapid palatal expansion: a case report

    Directory of Open Access Journals (Sweden)

    Miller Paul

    2012-12-01

    Full Text Available Abstract Introduction To the best of our knowledge, this is the first report of a case of treatment-resistant depression in which the patient was evaluated for sleep disordered breathing as the cause and in which rapid palatal expansion to permanently treat the sleep disordered breathing produced a prolonged symptom-free period off medication. Case presentation An 18-year-old Caucasian man presented to our sleep disorders center with chronic severe depression that was no longer responsive to medication but that had recently responded to electroconvulsive therapy. Ancillary, persistent symptoms included mild insomnia, moderate to severe fatigue, mild sleepiness and severe anxiety treated with medication. Our patient had no history of snoring or witnessed apnea, but polysomnography was consistent with upper airway resistance syndrome. Although our patient did not have an orthodontic indication for rapid palatal expansion, rapid palatal expansion was performed as a treatment of his upper airway resistance syndrome. Following rapid palatal expansion, our patient experienced a marked improvement of his sleep quality, anxiety, fatigue and sleepiness. His improvement has been maintained off all psychotropic medication and his depression has remained in remission for approximately two years following his electroconvulsive therapy. Conclusions This case report introduces the possibility that unrecognized sleep disordered breathing may play a role in adolescent treatment-resistant depression. The symptoms of upper airway resistance syndrome are non-specific enough that every adolescent with depression, even those responding to medication, may have underlying sleep disordered breathing. In such patients, rapid palatal expansion, by widening the upper airway and improving airflow during sleep, may produce a prolonged improvement of symptoms and a tapering of medication. Psychiatrists treating adolescents may benefit from having another treatment option for

  18. A witness breaks his silence: the meaning of a therapist's response to an adolescent's self-destruction.

    Science.gov (United States)

    Frankel, J

    2001-03-01

    I describe the case of a self-mutilating adolescent girl and my dilemma, as her therapist, about telling her parents about her self-abuse. I use two complementary, mutually enhancing relational theories of trauma--Ferenczi's (1933) and Davies and Frawley's (1994)--to help understand the minefield I was in. Davies and Frawley describe certain relational configurations that are typical of trauma victims. I believe that it is not only unavoidable but therapeutically vital for therapists to participate in these configurations so they can know the patient's experience in a personal way. It is also crucial that they be witnesses who provide recognition for the patient's pain and, in so doing, relieve the intolerable feeling of isolation that Ferenczi proposed was the most basic trauma. In addition, I discuss the observation that some people who have not been previously traumatized in any gross way manifest characteristics of trauma. PMID:11441515

  19. Eye movement desensitization and reprocessing for treating psychological disturbances in Taiwanese adolescents who experienced Typhoon Morakot.

    Science.gov (United States)

    Tang, Tze-Chun; Yang, Pinchen; Yen, Cheng-Fang; Liu, Tai-Ling

    2015-07-01

    In this case-control study, we aimed to assess the intervention effects of four-session eye movement desensitization and reprocessing (EMDR) on reducing the severity of disaster-related anxiety, general anxiety, and depressive symptoms in Taiwanese adolescents who experienced Typhoon Morakot. A total of 83 adolescents with posttraumatic stress disorder related to Typhoon Morakot, major depressive disorder, or current moderate or high suicide risk after experiencing Typhoon Morakot were allocated to a four-session course of EMDR (N = 41) or to treatment as usual (TAU; N = 42). A multivariate analysis of covariance was performed to examine the effects of EMDR in reducing the severity of disaster-related anxiety, general anxiety, and depressive symptoms in adolescents by using preintervention severity values as covariates. The multivariate analysis of covariance results indicated that the EMDR group exhibited significantly lower preintervention severity values of general anxiety and depression than did the TAU group. In addition, the preintervention severity value of disaster-related anxiety in the EMDR group was lower than that in the TAU group (p = 0.05). The results of this study support that EMDR could alleviate general anxiety and depressive symptoms and reduce disaster-related anxiety in adolescents experiencing major traumatic disasters. PMID:26162817

  20. Neurological, Metabolic, and Psychiatric Adverse Events in Children and Adolescents Treated With Aripiprazole.

    Science.gov (United States)

    Jakobsen, Klaus Damgaard; Bruhn, Christina Hedegaard; Pagsberg, Anne-Katrine; Fink-Jensen, Anders; Nielsen, Jimmi

    2016-10-01

    Aripiprazole is a partial dopamine agonist with only minor neurological and psychiatric adverse effects, making it a potential first-line drug for the treatment of psychiatric disorders. However, the evidence of its use in children and adolescents is rather sparse. The aim of this case study is to discuss adverse drug reaction (ADR) reports concerning aripiprazole-associated neurological and psychiatric events in children and adolescents. The ADR report database at Danish Medicines Agency was searched for all ADRs involving children and adolescents (disorders (PS group) and nonpsychotic disorders (non-PS group). The PS group consisted of 5 patients with schizophrenia and psychoses, not otherwise specified; and the non-PS group consisted of fourteen cases including autism spectrum disorders, attention deficit and hyperactivity disorder, obsessive-compulsive disorder, and Tourette syndrome. The main reported adverse effects in the non-PS group were chronic insomnia, Parkinsonism, behavioral changes psychoses, and weight gain, whereas the adverse effects in the PS group was predominantly anxiety, convulsions, and neuroleptic malignant syndrome. Although aripiprazole is considered safe and well tolerated in children and adolescents, severe adverse events as neuroleptic malignant syndrome, extreme insomnia, and suicidal behavior has been reported to health authorities. Clinicians should pay attention to these possible hazards when prescribing aripiprazole to this vulnerable group of patients. PMID:27504593

  1. An Integrative Conceptual Framework for Assessing and Treating Suicidal Behavior in Adolescents.

    Science.gov (United States)

    Rudd, M. David; Joiner, Thomas E., Jr.

    1998-01-01

    An integrative conceptual framework is provided for ongoing assessment and day-to-day treatment of suicidal adolescents. Goals are to provide a summary of therapeutic and assessment tasks consistent with existing standards of care and supported by empirical findings and to emphasize the roles, tasks, demands, and limitations of psychotherapy with…

  2. Reduction of Drug Abuse in Adolescents Previously Treated with Stimulants for ADHD

    Directory of Open Access Journals (Sweden)

    J Gordon Millichap

    2008-11-01

    Full Text Available The effects of early stimulant medication on subsequent risk for cigarette smoking and substance use disorders (SUDs were evaluated in a 5-year, case-controlled, follow-up study of adolescent girls with ADHD at the Pediatric Psychopharmacology Program, Masachusetts General Hospital, Boston, MA, and Department of Psychiatry, New York State University, Syracuse, NY.

  3. Severe hypertension due to renal polar artery stenosis in an adolescent treated with coil embolization

    Energy Technology Data Exchange (ETDEWEB)

    Docx, Martine K. [Koningin Paola Kinderziekenhuis, Department of Paediatrics, Chronic Diseases and Hypertension, Antwerp (Belgium); Vandenberghe, Philippe [Koningin Paola Kinderziekenhuis, Department of Paediatric Cardiology, Antwerp (Belgium); Maleux, Geert [University Hospitals Leuven, Department of Radiology, Leuven (Belgium); Gewillig, Marc [University Hospitals Leuven, Department of Paediatric Cardiology, Leuven (Belgium); Mertens, Luc [Hospital for Sick Children, Paediatric Cardiology, Toronto (Canada)

    2009-11-15

    A 12-year-old boy presented with severe arterial hypertension due to a severe subsegmental renal artery stenosis. Treatment consisted of selective embolization of the stenosed polar artery, which resulted in near normalization of the arterial pressures. Renal artery stenosis should always be considered, even in young adolescents, as a cause for arterial hypertension. Only selective angiography was able to demonstrate the subsegmental artery stenosis in this patient. (orig.)

  4. Neurological, Metabolic, and Psychiatric Adverse Events in Children and Adolescents Treated With Aripiprazole

    DEFF Research Database (Denmark)

    Jakobsen, Klaus Damgaard; Bruhn, Christina Hedegaard; Pagsberg, Anne-Katrine;

    2016-01-01

    insomnia, Parkinsonism, behavioral changes psychoses, and weight gain, whereas the adverse effects in the PS group was predominantly anxiety, convulsions, and neuroleptic malignant syndrome. Although aripiprazole is considered safe and well tolerated in children and adolescents, severe adverse events as...... neuroleptic malignant syndrome, extreme insomnia, and suicidal behavior has been reported to health authorities. Clinicians should pay attention to these possible hazards when prescribing aripiprazole to this vulnerable group of patients....

  5. Peer relations scale for adolescents treated for substance use disorder: a factor analytic presentation

    Directory of Open Access Journals (Sweden)

    Yao Ping

    2012-07-01

    Full Text Available Abstract Background The literature indicates that peer relations are an important aspect of the treatment and recovery of adolescents with substance use disorder (SUD. Unfortunately, no standard measure of peer relations exists. The objective of this research is to use exploratory factor analysis to examine the underlying factor structure of a 14-item peer relations scale for use in this treatment population. Methods Participants are 509 adolescents discharged from primary substance abuse treatment from 2003–2010. The data are from research conducted between six and twelve months post discharge via a 230-item questionnaire that included the 14-item peer relations scale. The scale has questions that assess the degree to which the adolescent's social contacts conform to norms of positive behavior and therefore foster non-use and recovery. The response rate was 62%. Results The scale was decomposed by principal component factor analysis. When the matrix was rotated by varimax a three factor solution explaining 99.99% of the common variance emerged. The first factor yielded ten items that measure association with peers who engage in positive versus delinquent social behavior (positive versus negative social behavior. The three items in the second factor specify association with peers who use versus those who don’t use drugs, and thereby encourage recovery and discourage drug use (drug use. The third and factor contained two items measuring the degree to which the recovering adolescent associates with new or previous friends (post treatment peer association. Conclusions This scale is useful as a standard measure in that it begins to identify the measurable dimensions of peer relations that influence sustaining post treatment recovery.

  6. Treating paternal drug abuse using Learning Sobriety Together: Effects on adolescents versus children

    OpenAIRE

    Kelley, Michelle L.; Fals-Stewart, William

    2007-01-01

    The focus of this study was whether couples-based treatment for substance abuse had comparable secondary benefits on the internalizing and externalizing behaviors of adolescent versus child siblings living in their homes. Couples took part in a couples-based treatment for substance abuse that combines Behavioral Couples Therapy and individual counseling (i.e., Learning Sobriety Together). During a 17-month assessment period, the relationship between parents’ functioning (i.e., fathers’ drug u...

  7. Un juego de cartas durante los recreos escolares mejora los hábitos alimentarios en adolescentes A school breaks card game improves eating habits in adolescents

    Directory of Open Access Journals (Sweden)

    I. J. Pérez López

    2012-12-01

    Full Text Available Introducción: Los hábitos alimentarios de la población española son un problema cada vez más preocupante en la actualidad y, en especial, durante la adolescencia. Objetivos: Mejorar los hábitos alimentarios saludables (desayuno, ingestas de fruta y agua, consumo de refrescos, bollería-golosinas y fritos en adolescentes. Métodos: La intervención se llevó a cabo durante 3 meses, con alumnos de entre 12 y 16 años, mediante una propuesta educativa a través de un juego de cartas (construido ad hoc, denominado "Fighting for my health", y que se desarrolló en los recreos escolares. Éste se complementó con la metodología del compromiso saludable, caracterizado fundamentalmente por el trabajo colaborativo entre escuela y familia y por el fomento de la responsabilidad del alumnado hacia su salud. Se contó con 2 grupos (experimental y control, cada uno de ellos con un número total de 48 adolescentes. Resultados: Tras la puesta en práctica de la intervención se lograron mejoras significativas en 5 de los 6 hábitos trabajados (la excepción fue el consumo de fritos en el grupo experimental. Entre ellas sobresale especialmente la diferencia altamente significativa (p Introduction: Feeding habits among the Spanish population are currently an increasing and concerning problem, especially during adolescence. Objectives: To improve feeding habits (breakfast, consumption of fruit and water, soft drinks, pastries, sweets and fried food in adolescents. Methods: The intervention was conducted for 3 months in students from 12 to 16 years old, through an educational proposal based on a card game (built ad hoc called "Fighting for my health", which was developed during the school breaks. This game was supplemented with the methodology of a healthy commitment, based mainly on the cooperative work between schools and families and the promotion of the responsibility among students about their health. Two groups were included (intervention and control

  8. The outcome and prognosis factors of adolescent nasopharyngeal carcinoma treated in a single institute-analysis of 148 patients

    International Nuclear Information System (INIS)

    Objective: To evaluate the clinical characteristics, outcome and prognostic factors of adolescent nasopharyngeal carcinoma. Methods: Between Jan 1990 and Dec 2009, totally 148 pathological confirmed nasopharyngeal carcinoma (NPC) patients with age ≤20 years were treated in our hospital, including stage II 8, stage III 58, stage IV 81, and unknown 1 when restaged by TNM system (UICC 2002), ninety-four (63.5%) patients were treated with radiotherapy alone, 54 (36.5%)patients were treated with radiotherapy combined with cisplatin-based chemotherapy. Results: The median follow-up time for all patients was 44.5 months. The 5-year overall survival (OS), local-regional control (LRC) and distant metastasis-free survival (DMFS) rates were 82.9%, 85.1% and 78.6%. There were 42 patients (28.4%) failed with 16 regional recurrence and 29 distant metastasis, and 3 with both; bone metastasis was the most common site of distant metastasis(22/29). In univariate analysis,the adverse prognostic factors for OS were stage T4(χ2=5.61, P=0.018), radiation dose 2=5.30, P=0.021), for LRC was radiation dose 2=4.24, P=0.039). In multivariate analysis, radiation dose 4 were the independent prognostic factors for OS (χ2=5.73, 5.56, P=0.017, 0.018), for LRC was radiation dose 2=5.81, P=0.016). Conclusions: The outcome of the present series was excellent, total nasopharyngeal radiation dose less than 70 Gy is inappropriate. Reduce the distant metastasis and late toxicities were the future direction for the treatment of adolescent nasopharyngeal carcinoma. (authors)

  9. Breaking Bat

    Science.gov (United States)

    Aguilar, Isaac-Cesar; Kagan, David

    2013-01-01

    The sight of a broken bat in Major League Baseball can produce anything from a humorous dribbler in the infield to a frightening pointed projectile headed for the stands. Bats usually break at the weakest point, typically in the handle. Breaking happens because the wood gets bent beyond the breaking point due to the wave sent down the bat created…

  10. Dying after cure: A case of suicide in an adolescent treated for cancer

    Directory of Open Access Journals (Sweden)

    Laura Veneroni

    2015-01-01

    Full Text Available Although suicide among childhood cancer survivors is rare, there is still a significantly higher risk in this population than in healthy adolescents. A 17-year-old girl cured of Burkitt lymphoma committed suicide after completing her treatment. She had never previously shown signs of psychological suffering and was in good general health. This case made the operators wonder how this tragic possibility might be prevented. It is essential for the ongoing monitoring of the psychological and social suffering of young people during follow-up programs to be assured by a multidisciplinary team involved in the patient′s global care.

  11. Nutritional assessment and lipid profile in HIV-infected children and adolescents treated with highly active antiretroviral therapy

    Directory of Open Access Journals (Sweden)

    Marina Hjertquist Tremeschin

    2011-06-01

    Full Text Available INTRODUCTION: HIV-infected children and adolescents treated with highly active antiretroviral therapy (HAART regimens that include a protease inhibitor (PI can show significant improvements in clinical outcomes, nutritional status and quality of life. The study aimed to report nutritional and metabolic alterations for pediatric patients continuously exposed to HAART and for healthy controls for up to 1 year. METHODS: Clinical, anthropometric, lipid profile and food intake data were collected prospectively over approximately 12-months for each patient. RESULTS: Fifty-one individuals were studied, of these, 16 were healthy. After 12 months follow-up, HIV-positive individuals remained below the healthy control group parameters. No change was observed concerning food intake. Triglyceride serum levels were higher in patients using protease inhibitor at the onset of the study [PI groups: 114 (43 - 336, and 136 (63 - 271 versus control group: 54.5 (20 - 162; p = 0.003], but after twelve months follow-up, only the group using protease inhibitor for up to two months presented higher values [140 (73 - 273 versus 67.5 (33 - 117; p = 0.004]. HDL-cholesterol was lower in HIV-positive individuals [HIV-positive groups: 36 (27 - 58 and 36 (23 - 43; control 49.5 (34 - 69; p = 0.004]. CONCLUSIONS: HIV-infected children and adolescents treated with highly active antiretroviral therapy showed compromised nutritional parameters compared to a paired healthy control group. Individuals using protease inhibitor presented worse triglyceride serum levels compared to their healthy counterparts.

  12. Effects of treating gender dysphoria and anorexia nervosa in a transgender adolescent: Lessons learned.

    Science.gov (United States)

    Strandjord, Sarah E; Ng, Henry; Rome, Ellen S

    2015-11-01

    Patients with gender dysphoria and patients with eating disorders often experience discontent with their bodies. Several reports have recognized the co-occurrence of these two conditions, typically in adults who identify as transgender females and desire a more feminine physique. This case report, in contrast, describes a 16-year-old patient with a female sex assigned at birth who first presented with features consistent with anorexia nervosa and later revealed underlying gender dysphoria with a drive for a less feminine body shape. We discuss both the path to recognizing gender dysphoria in this patient as well as the impact of treatment on his eating disorder and overall well-being. This case is one of only a few reports describing a female-to-male transgender patient with an eating disorder and is the first to explore the effects of hormone and surgical intervention in an adolescent patient. PMID:26337148

  13. Drug Reaction With Eosinophilia and Systemic Symptoms (DRESS) in an Adolescent Treated With Lamotrigine.

    Science.gov (United States)

    Ginory, Almari; Chaney-Catchpole, Michelle; Demetree, Julie M; Mayol Sabatier, Laura M; Nguyen, Mathew

    2013-07-01

    Drug reaction with eosinophilia and systemic symptoms (DRESS) is a hypersensitivity syndrome most commonly associated with antiepileptic agents, allopurinol, and sulfonamides. It is a severe adverse reaction associated with fever, rash, eosinophilia, lymphadenopathy, and internal organ involvement. We present the case of a 17-year-old Caucasian female with bipolar disorder type II and posttraumatic stress disorder treated with lamotrigine for a non-Food and Drug Administration-approved indication that developed DRESS syndrome at an initial dose higher than that recommended. Her symptoms were atypical in that she developed a rash with influenza-like symptoms that resolved after discontinuation of lamotrigine and returned 8 days later. She was hospitalized because of elevated liver enzymes and treated with corticosteroids. In patients presenting with rash and systemic symptoms, DRESS syndrome should be considered and treated appropriately to reduce mortality, which can be as high as 10%. Treatment includes withdrawal of the offending agent and corticosteroids. PMID:24052787

  14. Adolescent Spasmodic Torticollis Treated by Moxibustion——A Report on 30 Cases

    Institute of Scientific and Technical Information of China (English)

    Zhou Liwu

    2007-01-01

    @@ Spasmodic torticollis is characterized by involuntary contraction of the cervical muscles and the patient will have uni-directional paroxysmal vibration of the neck. The author has treated the disease by applying moxibustion and achieved quite satisfactory therapeutic effects. A report follows.

  15. Drug Reaction With Eosinophilia and Systemic Symptoms (DRESS) in an Adolescent Treated With Lamotrigine

    OpenAIRE

    Ginory, Almari; Chaney-Catchpole, Michelle; Demetree, Julie M.; Mayol Sabatier, Laura M.; Nguyen, Mathew

    2013-01-01

    Drug reaction with eosinophilia and systemic symptoms (DRESS) is a hypersensitivity syndrome most commonly associated with antiepileptic agents, allopurinol, and sulfonamides. It is a severe adverse reaction associated with fever, rash, eosinophilia, lymphadenopathy, and internal organ involvement. We present the case of a 17-year-old Caucasian female with bipolar disorder type II and posttraumatic stress disorder treated with lamotrigine for a non-Food and Drug Administration-approved indica...

  16. The epidemiology of pharmacologically treated attention deficit hyperactivity disorder (ADHD) in children, adolescents and adults in UK primary care

    LENUS (Irish Health Repository)

    McCarthy, Suzanne

    2012-06-19

    AbstractBackgroundAttention Deficit Hyperactivity Disorder (ADHD) is a common neurodevelopmental disorder characterised by the symptoms of inattention, impulsivity and hyperactivity. ADHD was once perceived as a condition of childhood only; however increasing evidence has highlighted the existence of ADHD in older adolescents and adults. Estimates for the prevalence of ADHD in adults range from 2.5–4%. Few data exist on the prescribing trends of the stimulants methylphenidate and dexamfetamine, and the non-stimulant atomoxetine in the UK. The aim of this study was to investigate the annual prevalence and incidence of pharmacologically treated ADHD in children, adolescents and adults in UK primary care.MethodsThe Health Improvement Network (THIN) database was used to identify all patients aged over 6 years with a diagnosis of ADHD\\/hyperkinetic disorder and a prescription for methylphenidate, dexamfetamine or atomoxetine from 2003–2008. Annual prevalence and incidence of pharmacologically treated ADHD were calculated by age category and sex.ResultsThe source population comprised 3,529,615 patients (48.9% male). A total of 118,929 prescriptions were recorded for the 4,530 patients in the pharmacologically treated ADHD cohort during the 6-year study. Prevalence (per 1000 persons in the mid-year THIN population) increased within each age category from 2003 to 2008 [6–12 years: from 4.8 (95% CI: 4.5–5.1) to 9.2 (95% CI: 8.8–9.6); 13–17 years: from 3.6 (95% CI: 3.3–3.9) to 7.4 (95% CI: 7.0–7.8); 18–24 years: from 0.3 (95% CI: 0.2–0.3) to 1.1 (95% CI: 1.0–1.3); 25–45 years: from 0.02 (95% CI: 0.01–0.03) to 0.08 (95% CI: 0.06–0.10); >45 years: from 0.01 (95% CI: 0.00–0.01) to 0.02 (95% CI: 0.01–0.03). Whilst male patients aged 6-12 years had the highest prevalence; the relative increase in prescribing was higher amongst female patients of the same age - the increase in prevalence in females aged 6–12 years was 2.1 fold

  17. The epidemiology of pharmacologically treated attention deficit hyperactivity disorder (ADHD in children, adolescents and adults in UK primary care

    Directory of Open Access Journals (Sweden)

    McCarthy Suzanne

    2012-06-01

    Full Text Available Abstract Background Attention Deficit Hyperactivity Disorder (ADHD is a common neurodevelopmental disorder characterised by the symptoms of inattention, impulsivity and hyperactivity. ADHD was once perceived as a condition of childhood only; however increasing evidence has highlighted the existence of ADHD in older adolescents and adults. Estimates for the prevalence of ADHD in adults range from 2.5–4%. Few data exist on the prescribing trends of the stimulants methylphenidate and dexamfetamine, and the non-stimulant atomoxetine in the UK. The aim of this study was to investigate the annual prevalence and incidence of pharmacologically treated ADHD in children, adolescents and adults in UK primary care. Methods The Health Improvement Network (THIN database was used to identify all patients aged over 6 years with a diagnosis of ADHD/hyperkinetic disorder and a prescription for methylphenidate, dexamfetamine or atomoxetine from 2003–2008. Annual prevalence and incidence of pharmacologically treated ADHD were calculated by age category and sex. Results The source population comprised 3,529,615 patients (48.9% male. A total of 118,929 prescriptions were recorded for the 4,530 patients in the pharmacologically treated ADHD cohort during the 6-year study. Prevalence (per 1000 persons in the mid-year THIN population increased within each age category from 2003 to 2008 [6–12 years: from 4.8 (95% CI: 4.5–5.1 to 9.2 (95% CI: 8.8–9.6; 13–17 years: from 3.6 (95% CI: 3.3–3.9 to 7.4 (95% CI: 7.0–7.8; 18–24 years: from 0.3 (95% CI: 0.2–0.3 to 1.1 (95% CI: 1.0–1.3; 25–45 years: from 0.02 (95% CI: 0.01–0.03 to 0.08 (95% CI: 0.06–0.10; >45 years: from 0.01 (95% CI: 0.00–0.01 to 0.02 (95% CI: 0.01–0.03. Whilst male patients aged 6-12 years had the highest prevalence; the relative increase in prescribing was higher amongst female patients of the same age - the increase in prevalence in females aged 6–12 years was 2

  18. Quality of life in Danish children and adolescents with type 1 diabetes treated with continuous subcutaneous insulin infusion or multiple daily injections

    DEFF Research Database (Denmark)

    Birkebæk, Niels; Kristensen, Lene Juel; Mose, Anne; Thastum, Mikael

    2014-01-01

    investigate whether HRQoL assessments were influenced by treatment duration. METHODS: Participants were recruited through the Danish Registry for Diabetes in Childhood and Adolescence. A total of 700 children and adolescents (360 girls), 8-17 years, were included. Of these, 295 were treated with CSII (160 for...... diabetes-related symptoms and worry, less problems in communicating diabetes, and better generic functioning compared with those on MDI. Children and adolescents on CSII for more than one year reported less diabetes-related symptoms, but more treatment problems, and better generic functioning in all...... subscales except social functioning compared with those on MDI for more than one year. Comparing those on CSII and MDI for less than one year, no differences in HRQoL ratings were found, apart from better rating of treatment barriers in the MDI group. CONCLUSIONS: This Danish national study on HRQoL in...

  19. Perception of stress level, trunk appearance, body function and mental health in females with adolescent idiopathic scoliosis treated conservatively: a longitudinal analysis

    OpenAIRE

    Misterska, Ewa; Glowacki, Maciej; Latuszewska, Joanna; Adamczyk, Katarzyna

    2012-01-01

    Purpose In the presented study, we aimed to assess changes over time in the perception of trunk deformity, body function, stress level and mental health in females with adolescent idiopathic scoliosis (AIS) who were treated conservatively with a Cheneau brace, taking the Trunk Appearance Perception Scale (TAPS), Scoliosis Research Society-22 (SRS-22) and Bad Sobberheim Stress Questionnaires (BSSQ) criteria of evaluation into consideration. Methods The study design was comprised of three quest...

  20. Long-Term Quality of Life and Pregnancy Outcomes of Differentiated Thyroid Cancer Survivors Treated by Total Thyroidectomy and I131 during Adolescence and Young Adulthood

    OpenAIRE

    Metallo, Melanie; Groza, Lelia; Brunaud, Laurent; Klein, Marc; Weryha, Georges; Feigerlova, Eva

    2016-01-01

    Introduction. Differentiated thyroid cancer (DTC) is rare and confers good prognosis. Long-term health related quality of life (HRQoL) and pregnancy outcomes are not well known in subjects treated during adolescence and young adulthood. Methods. Cross-sectional analysis of HRQoL and global self-esteem, using SF-36 and ISP-25 surveys, and of pregnancy outcomes in female survivors of DTC treated by total thyroidectomy and I131 before age of 25 years. Results. Forty-five of 61 patients (74%) res...

  1. String breaking

    CERN Document Server

    Bali, G S; Lippert, T; Neff, H; Prkacin, Z; Schilling, K; Bali, Gunnar S; Dussel, Thomas; Lippert, Thomas; Neff, Hartmut; Prkacin, Zdravko; Schilling, Klaus

    2006-01-01

    We numerically investigate the transition of the static quark-antiquark string into a static-light meson-antimeson system. Improving noise reduction techniques, we are able to resolve the signature of string breaking dynamics for Nf=2 lattice QCD at zero temperature. We discuss the lattice techniques used and present results on energy levels and mixing angle of the static two-state system. We visualize the action density distribution in the region of string breaking as a function of the static colour source-antisource separation. The results can be related to properties of quarkonium systems.

  2. Supersymmetry breaking

    Indian Academy of Sciences (India)

    Emilian Dudas

    2009-01-01

    We review the various mechanisms of supersymmetry breaking and its trans-mission to the observable sector. We argue that hybrid models where gauge dominates over gravity mediation, but gravity provides the main contributions to the Higgs sector masses and the neutralino mass, are able to combine the advantages and reduce the disadvantages of the two transmission mechanisms.

  3. The Break

    DEFF Research Database (Denmark)

    Strand, Anete Mikkala Camille

    2016-01-01

    The chapter elaborates on how to deal with one of the major challenges facing organizations worldwide; Stress. The Break enacts a quantum approach to meet the challenges by proposing a combination of three different quantum storytelling technologies; protreptic mentoring, walking and material sto...... provider and witness to your elaborations. It’s really that simple! The chapter concludes towards a set of Dogmas for future reference in addressing these challenges in this manner....

  4. Outcome and pathologic classification of children and adolescents with mediastinal large B-cell lymphoma treated with FAB/LMB96 mature B-NHL therapy

    OpenAIRE

    Gerrard, Mary; Waxman, Ian M.; Sposto, Richard; Auperin, Anne; Perkins, Sherrie L.; Goldman, Stanton; Harrison, Lauren; Pinkerton, Ross; McCarthy, Keith; Raphael, Martine; Patte, Catherine; Cairo, Mitchell S

    2013-01-01

    Mediastinal large B-cell lymphoma (MLBL) represents 2% of mature B-cell non-Hodgkin lymphoma in patients ≤ 18 years of age. We analyzed data from childhood and adolescent patients with stage III MLBL (n = 42) and non-MLBL DLBCL (n = 69) treated with Group B therapy in the French-American-British/Lymphome Malins de Burkitt (FAB/LMB) 96 study. MLBL patients had a male/female 26/16; median age, 15.7 years (range, 12.5-19.7); and LDH < 2 versus ≥ 2 × the upper limit of normal, 23:19. Six MLBL pat...

  5. Adolescent External Iliac Artery Trauma: Recurrent Aneurysmal Dilatation of an Iliofemoral Saphenous Vein Graft Treated by Stent-Grafting

    International Nuclear Information System (INIS)

    An adolescent male sustained a severe penetrating injury to the external iliac artery. Emergency surgical revascularization was with a reversed long saphenous vein interposition graft. The primary graft and the subsequent revision graft both became aneurysmal. The second graft aneurysm was successfully excluded by endovascular stent-grafts with medium-term primary patency. A venous graft was used initially rather than a synthetic graft to reduce the risk of infection and the potential problems from future growth. Aneurysmal dilatation of venous grafts in children and adolescents is a rare but recognized complication. To the best of our knowledge, exclusion of these aneurysms with stent-grafts has not been previously reported in the adolescent population.

  6. Commentary: Making the brain matter in assessing and treating adolescent substance use--a commentary on Conrod and Nikolaou (2016).

    Science.gov (United States)

    Mosconi, Matthew W; Lejuez, Carl W

    2016-03-01

    Adolescence represents a period of vulnerability to psychiatric problems due to a range of factors, including advances in social and cognitive abilities, increased levels of autonomy in decision-making and behavioral governance, and greater exposure to opportunities for risk-taking behavior. Adding to these psychological and social challenges, adolescence also is marked by robust maturational changes affecting both the microcircuitry and connectivity between widely distributed brain systems. These changes alter the communication among parallel, distributed brain networks, have implications for one's vulnerability to engage in risk behavior and make the brain particularly susceptible to external perturbations, such as exposure to neurotoxic substances. PMID:26889899

  7. Impact of long-term use of eHealth systems in adolescents with type 1 diabetes treated with sensor-augmented pump therapy.

    Science.gov (United States)

    Schiaffini, R; Tagliente, I; Carducci, C; Ullmann, N; Ciampalini, P; Lorubbio, A; Cappa, M

    2016-07-01

    Telemedicine in diabetes includes telemonitoring and transmission of important data (self monitoring of blood glucose data, insulin therapy, pump setting, etc.) from the patient s home to the diabetic unit, with a real-time health feedback. Moreover, an eHealth approach is thought to facilitate diabetes management and to improve compliance to CSII/SAP treatment in adolescents, but to date, limited literature related to this topic is available and long-term studies are still lacking. The main aim of this study was to compare the long-term effect on glycometabolic control of eHealth intervention and traditional care in T1DM SAP-treated adolescents. In our study we demonstrated a favorable impact of monthly teleassistance on treatment compliance. Adolescents receiving frequent feedback provided by the medicalmultidisciplinary team, due to the telemonitoring, resulted more compliant in self-management of diabetes. In particular, the medical team feedback resulted in interventions on behavioral errors and insulin therapy adjustments, leading to an improved glycometabolic control. PMID:26289613

  8. Breaking Symmetries

    CERN Document Server

    Peters, Kirstin

    2010-01-01

    A well-known result by Palamidessi tells us that {\\pi}mix (the {\\pi}-calculus with mixed choice) is more expressive than {\\pi}sep (its subset with only separate choice). The proof of this result argues with their different expressive power concerning leader election in symmetric networks. Later on, Gorla of- fered an arguably simpler proof that, instead of leader election in symmetric networks, employed the reducibility of "incestual" processes (mixed choices that include both enabled senders and receivers for the same channel) when running two copies in parallel. In both proofs, the role of breaking (ini- tial) symmetries is more or less apparent. In this paper, we shed more light on this role by re-proving the above result-based on a proper formalization of what it means to break symmetries-without referring to another layer of the distinguishing problem domain of leader election. Both Palamidessi and Gorla rephrased their results by stating that there is no uniform and reason- able encoding from {\\pi}mix i...

  9. The Break

    DEFF Research Database (Denmark)

    Strand, Anete Mikkala Camille; Larsen, Jens

    2015-01-01

    to Explore your Leadership” . ”Time to reflect closer to heaven as we did in the Pyrenees, makes me humble and simplifies the thoughts on how to lead within my own set of values. It´s all about energy”, (Lars Lund Hansen, manager, Novo Nordisk) A few objects; a neckless, a candle, a dragon and five crystal...... terrain break elaborates the terrain of Organizations anno 2015 as a terrain of complexity, streamlining, language-orientation and dis-functionality. The latter in regard to a WHO acknowledged concern for health issues related to work-related stress (Prætorius, 2012) and an ongoing urge for learning...... that language and the social has been granted too much power on the dispense of the bodily, physical and biological – or in short, in dispense of the material. The break To be or not to be poses the theoretical notion of dis-/continuity (Barad, 2007, 2010) from the quantum approach to storytelling (Strand 2012...

  10. One-year outcome and incidence of anorexia nervosa and restrictive eating disorders among adolescent girls treated as out-patients in a family-based setting.

    Science.gov (United States)

    Rosling, Agneta; Salonen Ros, Helena; Swenne, Ingemar

    2016-01-01

    Aims To study the 1-year outcome and to analyse predictors of outcome of a cohort of adolescent girls with anorexia nervosa (AN) or restrictive eating disorders not otherwise specified (EDNOSr) treated as out-patients in a family-based programme at a specialized eating disorder service. To calculate the incidence of anorexia nervosa among treatment-seeking girls younger than 18 in Uppsala County from 2004 to 2006. Methods A total of 168 female patients were offered treatment, and 141 were followed-up 1 year after starting treatment, 29 with AN and 112 with EDNOSr. Results Of the 29 girls who initially had AN, 6 (20%) had a good outcome and were free of any form of eating disorder at follow-up; only 1 (3%) had AN. Of the patients with EDNOSr, 54 (48%) had a good outcome and were free of eating disorders. Three (3%) had a poor outcome and had developed AN. The incidence of AN was 18/100,000 person-years in girls younger than 12 and 63/100,000 in girls younger than 18. Conclusion Restrictive eating disorders, including AN, in children and adolescents can be successfully treated in a family-based specialized out-patient service without in-patient care. PMID:26915921

  11. One-year outcome and incidence of anorexia nervosa and restrictive eating disorders among adolescent girls treated as out-patients in a family-based setting

    Science.gov (United States)

    Rosling, Agneta; Salonen Ros, Helena; Swenne, Ingemar

    2016-01-01

    Aims To study the 1-year outcome and to analyse predictors of outcome of a cohort of adolescent girls with anorexia nervosa (AN) or restrictive eating disorders not otherwise specified (EDNOSr) treated as out-patients in a family-based programme at a specialized eating disorder service. To calculate the incidence of anorexia nervosa among treatment-seeking girls younger than 18 in Uppsala County from 2004 to 2006. Methods A total of 168 female patients were offered treatment, and 141 were followed-up 1 year after starting treatment, 29 with AN and 112 with EDNOSr. Results Of the 29 girls who initially had AN, 6 (20%) had a good outcome and were free of any form of eating disorder at follow-up; only 1 (3%) had AN. Of the patients with EDNOSr, 54 (48%) had a good outcome and were free of eating disorders. Three (3%) had a poor outcome and had developed AN. The incidence of AN was 18/100,000 person-years in girls younger than 12 and 63/100,000 in girls younger than 18. Conclusion Restrictive eating disorders, including AN, in children and adolescents can be successfully treated in a family-based specialized out-patient service without in-patient care. PMID:26915921

  12. Clinical audit on "Evaluation of special issues in adolescents with cancer treated in an adult cancer setting": An Indian experience

    Directory of Open Access Journals (Sweden)

    Naveen S Salins

    2012-01-01

    Results: Pain was the most common physical symptom seen in all 10 patients. 3 out of 10 patients were involved in decision making, 3 out of 10 patients had identity issues and 4 out of 10 patients had peer group isolation issues. Only 3 were aware of diagnosis and none were aware of treatment outcomes and mortality. 4 out of 10 had anxiety and depression and 3 out of 10 had body image issues. Sexuality, spiritual and existential issues were not explored in any of the patients studied. Conclusion: The outcomes of the study were in an adult oncology setting there was a poor recognition of key adolescent issues such as sexuality, body image, identity and peer group isolation. The psychosocial supports to these adolescents were minimal and spiritual and existential issues were not explored. The inferences drawn from this study suggested a need for multidisciplinary team approach oriented in handling adolescent care needs and preferably to have a dedicated space that will help the peer group to interact, bond and cope better with the illness.

  13. Mental Health of Adults Treated in Adolescence with Scoliosis-Specific Exercise Program or Observed for Idiopathic Scoliosis

    OpenAIRE

    Maciej Płaszewski; Igor Cieśliński; Roman Nowobilski; Tomasz Kotwicki; Jacek Terech; Mariusz Furgał

    2014-01-01

    Objective. To examine general mental health in adult males and females, who in adolescence participated in a scoliosis-specific therapeutic exercise program or were under observation due to diagnosis of scoliosis. Design. Registry-based, cross-sectional study with retrospective data collection. Methods. Sixty-eight subjects (43 women) aged 30.10 (25–39) years, with mild or moderate scoliosis (11–36° Cobb angle), and 76 (38 women) nonscoliotic subjects, aged 30.11 (24–38) years, participated. ...

  14. Long term outcome of adolescent and adult patients with pineal parenchymal tumors treated with fractionated radiotherapy between 1982 and 2003 -- a single institution's experience

    International Nuclear Information System (INIS)

    To evaluate the effectivity of fractionated radiotherapy in adolescent and adult patients with pineal parenchymal tumors (PPT). Between 1982 and 2003, 14 patients with PPTs were treated with fractionated radiotherapy. 4 patients had a pineocytoma (PC), one a PPT with intermediate differentiation (PPTID) and 9 patients a pineoblastoma (PB), 2 of which were recurrences. All patients underwent radiotherapy on the primary tumor site with a median total dose of 54 Gy. In 9 patients with primary PB treatment included whole brain irradiation (3 patients) or irradiation of the craniospinal axis (6 patients) with a median total dose of 35 Gy. Median follow-up was 123 months in the PC patients and 109 months in the patients with primary PB. 7 patients were free from relapse at the end of follow-up. One PC patient died from spinal seeding. Among 5 PB patients treated with radiotherapy without chemotherapy, 3 developed local or spinal tumor recurrence. Both patients treated for PB recurrences died. The patient with PPTID is free of disease 7 years after radiotherapy. Local radiotherapy seems to be effective in patients with PC and some PPTIDs. Diagnosis and treatment of patients with more aggressive variants of PPTIDs as well as treatment of PB needs to be further improved, since local and spinal failure even despite craniospinal irradiation (CSI) is common. As PPT are very rare tumors, treatment within multi-institutional trials remains necessary

  15. Sustained First Remission in an Adolescent With Hepatosplenic T-Cell Lymphoma Treated With T-Cell Leukemia Induction, Nucleoside Analog-Based Consolidation, and Early Hematopoietic Stem Cell Transplant

    OpenAIRE

    Schafer, Eric; Chen, Allen; Arceci, Robert J.

    2009-01-01

    Hepatosplenic T-cell lymphoma (HTCL) is a rare malignancy. Prognosis is poor with only a few case reports of long-term survivors. While HTCL universally involves the bone marrow, the condition has been most often treated with multimodal lymphoma specific chemotherapy. We report a durable, sustained first remission in an adolescent treated for HTCL who received induction therapy according to a high risk T-cell leukemia regimen, a nucleoside analog-based consolidation, and allogeneic transplant...

  16. Early injury to cortical and cancellous bone from induction chemotherapy for adolescents and young adults treated for acute lymphoblastic leukemia.

    Science.gov (United States)

    Orgel, E; Mueske, N M; Wren, T A L; Gilsanz, V; Butturini, A M; Freyer, D R; Mittelman, S D

    2016-04-01

    Diminished bone density and skeletal fractures are common morbidities during and following therapy for acute lymphoblastic leukemia (ALL). While cumulative doses of osteotoxic chemotherapy for ALL have been reported to adversely impact bone density, the timing of onset of this effect as well as other changes to bone structure is not well characterized. We therefore conducted a prospective cohort study in pre-adolescent and adolescent patients (10-21years) newly diagnosed with ALL (n=38) to explore leukemia-related changes to bone at diagnosis and the subsequent impact of the first phase of chemotherapy ("Induction"). Using quantitative computerized tomography (QCT), we found that pre-chemotherapy bone properties were similar to age- and sex-matched controls. Subsequently over the one month Induction period, however, cancellous volumetric bone mineral density (vBMD) decreased markedly (-26.8%, ptibia -0.0%, p=0.860, femur -0.7%, p=0.290). The tibia underwent significant cortical thinning (average cortical thickness-1.2%, p<0.001; cortical area-0.4%, p=0.014), while the femur was less affected. Areal BMD (aBMD) concurrently measured by dual-energy X-ray absorptiometry (DXA) underestimated changes from baseline as compared to vBMD. Biochemical evidence revealed prevalent Vitamin D insufficiency and a net resorptive state at start and end of Induction. Our findings demonstrate for the first time that significant alterations to cancellous and cortical bone develop during the first month of treatment, far earlier during ALL therapy than previously considered. Given that osteotoxic chemotherapy is integral to curative regimens for ALL, these results provide reason to re-evaluate traditional approaches toward chemotherapy-associated bone toxicity and highlight the urgent need for investigation into interventions to mitigate this common adverse effect. PMID:26851412

  17. Long-term outcome of 25 children and adolescents with severe aplastic anemia treated with antithymocyte globulin

    Directory of Open Access Journals (Sweden)

    de-Medeiros C.R.

    2000-01-01

    Full Text Available Severe aplastic anemia (SAA is probably an immune-mediated disorder, and immunosuppressive therapy is recommended for patients with no available donor for bone marrow transplant. Between October 1984 and November 1987, 25 consecutive children and adolescents with SAA with no HLA-compatible marrow donor received equine antithymocyte globulin (ATG (15 mg kg-1 day-1 for 10 days. The patients were evaluated 6 weeks, 6 months, and 12 months after starting ATG treatment. Thereafter, patients were evaluated yearly until July 1998. Median age was 10 years (range, 1.5-20 years, granulocyte counts on referral ranged from 0.032 to 1.4 x 10(9/l (median 0.256 x 10(9/l, and 12 patients had granulocyte counts <0.2 x 10(9/l. At a median follow-up of 9.6 years (range, 8.6-11.8 years, 10 patients (40% remained alive with good marrow function. No morphologic evidence of hematological clonal disorders has been observed, although two patients probably have acquired clonal chromosomal abnormalities (trisomy 8 and del(6q21, respectively. Responses to ATG were observed between 6 weeks and 6 months from the start of treatment in 60% of evaluable patients. The response rate was not different in patients whose granulocyte count at diagnosis was <0.2 x 10(9/l, or in those who were <10 years of age. This study supports the view that, when compared with supportive measures, ATG is an effective treatment for children or adolescents with SAA. Although these results are inferior to those reported for marrow transplantation or more intensive immunosuppressive regimens, these patients who responded to ATG are long-term survivors with stable peripheral blood counts and a low rate of relapse.

  18. Long-Term Quality of Life and Pregnancy Outcomes of Differentiated Thyroid Cancer Survivors Treated by Total Thyroidectomy and I131 during Adolescence and Young Adulthood

    Directory of Open Access Journals (Sweden)

    Melanie Metallo

    2016-01-01

    Full Text Available Introduction. Differentiated thyroid cancer (DTC is rare and confers good prognosis. Long-term health related quality of life (HRQoL and pregnancy outcomes are not well known in subjects treated during adolescence and young adulthood. Methods. Cross-sectional analysis of HRQoL and global self-esteem, using SF-36 and ISP-25 surveys, and of pregnancy outcomes in female survivors of DTC treated by total thyroidectomy and I131 before age of 25 years. Results. Forty-five of 61 patients (74% responded to the survey. Cumulative I131 activity was ≤3.85 GBq in 18 subjects and >3.85 GBq in 27 subjects. Mean time from diagnosis was 7.6 ± 5.2 years for the group ≤ 3.85 GBq versus 16.9 ± 11.6 years for the group > 3.85 GBq (P 3.85 GBq and 10 in patients from the group ≤ 3.85 GBq. Frequency of miscarriages was of 17% (group > 3.85 GBq and 10% (group ≤ 3.85 GBq with 9 and 24 live births, respectively. No congenital malformations or first year mortality was noted. Conclusion. Long-term HRQoL, global self-esteem, and pregnancy outcomes are not affected in young female survivors of DTC.

  19. Consensus statement on the management of the GH-treated adolescent in the transition to adult care

    DEFF Research Database (Denmark)

    Clayton, P E; Cuneo, R C; Juul, A; Monson, J P; Shalet, S M; Tauber, M

    2005-01-01

    The European Society for Paediatric Endocrinology held a consensus workshop in Manchester, UK in December 2003 to discuss issues relating to the care of GH-treated patients in the transition from paediatric to adult life. Clinicians experienced in the care of paediatric and adult patients on GH t...

  20. Bootstrap Dynamical Symmetry Breaking

    Directory of Open Access Journals (Sweden)

    Wei-Shu Hou

    2013-01-01

    Full Text Available Despite the emergence of a 125 GeV Higgs-like particle at the LHC, we explore the possibility of dynamical electroweak symmetry breaking by strong Yukawa coupling of very heavy new chiral quarks Q . Taking the 125 GeV object to be a dilaton with suppressed couplings, we note that the Goldstone bosons G exist as longitudinal modes V L of the weak bosons and would couple to Q with Yukawa coupling λ Q . With m Q ≳ 700  GeV from LHC, the strong λ Q ≳ 4 could lead to deeply bound Q Q ¯ states. We postulate that the leading “collapsed state,” the color-singlet (heavy isotriplet, pseudoscalar Q Q ¯ meson π 1 , is G itself, and a gap equation without Higgs is constructed. Dynamical symmetry breaking is affected via strong λ Q , generating m Q while self-consistently justifying treating G as massless in the loop, hence, “bootstrap,” Solving such a gap equation, we find that m Q should be several TeV, or λ Q ≳ 4 π , and would become much heavier if there is a light Higgs boson. For such heavy chiral quarks, we find analogy with the π − N system, by which we conjecture the possible annihilation phenomena of Q Q ¯ → n V L with high multiplicity, the search of which might be aided by Yukawa-bound Q Q ¯ resonances.

  1. Refractory vasculitic ulcer of the toe in adolescent suffering from Systemic Lupus Erythematosus treated successfully with hyperbaric oxygen therapy

    Directory of Open Access Journals (Sweden)

    Mauro Angela

    2010-10-01

    Full Text Available Abstract Skin ulcers are a dangerous and uncommon complication of vasculitis. We describe the case of a teenager suffering from Systemic Lupus Erythematosus with digital ulcer resistant to conventional therapy, treated successfully with Hyperbaric Oxygen Therapy. The application of hyperbaric oxygen, which is used for the treatment of ischemic ulcers, is an effective and safe therapeutic option in patients with ischemic vasculitic ulcers in combination with immunosuppressive drugs. Further studies are needed to evaluate its role as primary therapy for this group of patients.

  2. Long-Term Quality of Life and Pregnancy Outcomes of Differentiated Thyroid Cancer Survivors Treated by Total Thyroidectomy and I(131) during Adolescence and Young Adulthood.

    Science.gov (United States)

    Metallo, Melanie; Groza, Lelia; Brunaud, Laurent; Klein, Marc; Weryha, Georges; Feigerlova, Eva

    2016-01-01

    Introduction. Differentiated thyroid cancer (DTC) is rare and confers good prognosis. Long-term health related quality of life (HRQoL) and pregnancy outcomes are not well known in subjects treated during adolescence and young adulthood. Methods. Cross-sectional analysis of HRQoL and global self-esteem, using SF-36 and ISP-25 surveys, and of pregnancy outcomes in female survivors of DTC treated by total thyroidectomy and I(131) before age of 25 years. Results. Forty-five of 61 patients (74%) responded to the survey. Cumulative I(131) activity was ≤3.85 GBq in 18 subjects and >3.85 GBq in 27 subjects. Mean time from diagnosis was 7.6 ± 5.2 years for the group ≤ 3.85 GBq versus 16.9 ± 11.6 years for the group > 3.85 GBq (P self-esteem was observed. Thirty pregnancies after I(131) were noted in patients from the group > 3.85 GBq and 10 in patients from the group ≤ 3.85 GBq. Frequency of miscarriages was of 17% (group > 3.85 GBq) and 10% (group ≤ 3.85 GBq) with 9 and 24 live births, respectively. No congenital malformations or first year mortality was noted. Conclusion. Long-term HRQoL, global self-esteem, and pregnancy outcomes are not affected in young female survivors of DTC. PMID:26977147

  3. Cost-effectiveness of extended-release methylphenidate in children and adolescents with attention-deficit/hyperactivity disorder sub-optimally treated with immediate release methylphenidate.

    Directory of Open Access Journals (Sweden)

    Jurjen van der Schans

    Full Text Available Attention-Deficit/Hyperactivity Disorder (ADHD is a common psychiatric disorder in children and adolescents. Immediate-release methylphenidate (IR-MPH is the medical treatment of first choice. The necessity to use several IR-MPH tablets per day and associated potential social stigma at school often leads to reduced compliance, sub-optimal treatment, and therefore economic loss. Replacement of IR-MPH with a single-dose extended release (ER-MPH formulation may improve drug response and economic efficiency.To evaluate the cost-effectiveness from a societal perspective of a switch from IR-MPH to ER-MPH in patients who are sub-optimally treated.A daily Markov-cycle model covering a time-span of 10 years was developed including four different health states: (1 optimal response, (2 sub-optimal response, (3 discontinued treatment, and (4 natural remission. ER-MPH options included methylphenidate osmotic release oral system (MPH-OROS and Equasym XL/Medikinet CR. Both direct costs and indirect costs were included in the analysis, and effects were expressed as quality-adjusted life years (QALYs. Univariate, multivariate as well as probabilistic sensitivity analysis were conducted and the main outcomes were incremental cost-effectiveness ratios.Switching sub-optimally treated patients from IR-MPH to MPH-OROS or Equasym XL/Medikinet CR led to per-patient cost-savings of €4200 and €5400, respectively, over a 10-year treatment span. Sensitivity analysis with plausible variations of input parameters resulted in cost-savings in the vast majority of estimations.This study lends economic support to switching patients with ADHD with suboptimal response to short-acting IR-MPH to long-acting ER-MPH regimens.

  4. Suicide attempts by exogenous intoxication among female adolescents treated at a reference hospital in the city of Recife-PE, Brazil

    OpenAIRE

    Juliana Lourenço de Araújo Veras; Cintia Regina Tornisiello Katz

    2011-01-01

    This study aimed to assess cases of self-inflicted poisoning among adolescents reported by the Toxicological Care Center of a reference hospital in Recife-PE, Brazil. The data were collected between March and May 2010 from hospital charts and structured interviews with the participants and parents/guardians. Among the 25 cases of attempted suicide registered in the period, 21 were female adolescents, who made up the sample of the present study. The adolescents were between 13 and 19 years of ...

  5. Electroweak symmetry breaking through supersymmetry breaking

    International Nuclear Information System (INIS)

    The connection between the scales of SU(2) x U(1) gauge symmetry breaking and supersymmetry breaking is didactically displayed in the framework of a T.O.Y. (Theory Overestimating Yukawas) model, a version of the (M + 1) SSM (supersymmetric extension of the standard model with a gauge singlet) in which the relevant parameters are determined in the fixed point regime. Some conspicuous features of supersymmetric particle physics are reviewed in the light of this simplified model. An alternative theory corresponding to lim (M + 1) SSM → MSSM, leads to interesting inequalities among the supersymmetric breaking parameters of the MSSM

  6. 意象对话技术治疗青少年抑郁症的疗效观察%Clinical Observation on Imagery Dialogue Technique in Treating Adolescence Depression

    Institute of Scientific and Technical Information of China (English)

    李翠萍; 杜圣英; 张旺信

    2013-01-01

    探讨意象对话技术对青少年抑郁症的疗效.150例青少年抑郁症患者分为3组,意象组:单纯意象对话技术治疗;药物组:帕罗西汀治疗;联合组:帕罗西汀辅助认知治疗.患者随访1年,用汉密顿抑郁量表进行评定.结果显示,意象对话技术对青少年抑郁症的疗效与帕罗西汀联合认知疗法疗效相当,比单用帕罗西汀疗效好.%To explore the effect of Imagery Dialogue Technique in the treatment of adolescence depression, 150 cases with adolescence depression were randomly divided into three groups. Imagery dialogue group: treated with only imagery dialogue technique; drug therapy groups; treated with Paroxetine; joint therapy groups: treated with Paroxetine and cognitive behavioral therapy and assessed by Hamilton depression scale. The results showed the effect of imagery dialogue technique on adolescence depression was equivalent to the effect of Paroxetine combined with cognitive and was better than the effect of Paroxetine.

  7. Chiral symmetry and chiral-symmetry breaking

    International Nuclear Information System (INIS)

    These lectures concern the dynamics of fermions in strong interaction with gauge fields. Systems of fermions coupled by gauge forces have a very rich structure of global symmetries, which are called chiral symmetries. These lectures will focus on the realization of chiral symmetries and the causes and consequences of thier spontaneous breaking. A brief introduction to the basic formalism and concepts of chiral symmetry breaking is given, then some explicit calculations of chiral symmetry breaking in gauge theories are given, treating first parity-invariant and then chiral models. These calculations are meant to be illustrative rather than accurate; they make use of unjustified mathematical approximations which serve to make the physics more clear. Some formal constraints on chiral symmetry breaking are discussed which illuminate and extend the results of our more explicit analysis. Finally, a brief review of the phenomenological theory of chiral symmetry breaking is presented, and some applications of this theory to problems in weak-interaction physics are discussed

  8. Onabotulinumtoxin A for Treating Overactive/Poor Compliant Bladders in Children and Adolescents with Neurogenic Bladder Secondary to Myelomeningocele

    Directory of Open Access Journals (Sweden)

    Antonio Marte

    2012-12-01

    Full Text Available This retrospective study was performed to verify the efficacy and safety of Onabotulinumtoxin A (BTX-A in treating children with neurogenic bladder (NB secondary to myelomeningocele (MMC with detrusor overactivity/low compliance. From January 2002 to June 2011, 47 patients out of 68 with neuropathic bladder were selected (22 females, 25 males, age range 5–17 years; mean age 10.7 years at first injection. They presented overactive/poor compliant neurogenic bladders on clean intermittent catheterization, and were resistant or non compliant to pharmacological therapy. Ten patients presented second to fourth grade concomitant monolateral/bilateral vesicoureteral reflux (VUR. All patients were incontinent despite catheterization. In the majority of patients Botulinum-A toxin was administered under general/local anesthesia by the injection of 200 IU of toxin, without exceeding the dosage of 12IU/kg body weight, diluted in 20 cc of saline solution in 20 sites, except in the periureteral areas. Follow-up included clinical and ultrasound examination, urodynamics performed at 6, 12 and 24 weeks, and annually thereafter. Seven patients remained stable, 21 patients required a second injection after 6–9 months and 19 a third injection. VUR was corrected, when necessary, in the same session after the BT-A injection, by 1–3 cc of subureteral Deflux®. Urodynamic parameters considered were leak point pressure (LPP, leak point volume (LPV and specific volume at 20 cm H2O pressure. The results were analyzed using the Wilcoxon test. All patients experienced a significant 66.45% average increase of LPV (Wilcoxon paired rank test = 7169 × 10 −10 and a significant 118.57% average increase of SC 20 (Wilcoxon paired rank test = 2.466 × 10 −12. The difference between preoperative and postoperative LPP resulted not significant (Wilcoxon paired rank test = 0.8858 No patient presented severe systemic complications; 38/47 patients presented slight hematuria for

  9. Onabotulinumtoxin A for treating overactive/poor compliant bladders in children and adolescents with neurogenic bladder secondary to myelomeningocele.

    Science.gov (United States)

    Marte, Antonio

    2013-01-01

    This retrospective study was performed to verify the efficacy and safety of Onabotulinumtoxin A (BTX-A) in treating children with neurogenic bladder (NB) secondary to myelomeningocele (MMC) with detrusor overactivity/low compliance. From January 2002 to June 2011, 47 patients out of 68 with neuropathic bladder were selected (22 females, 25 males, age range 5-17 years; mean age 10.7 years at first injection). They presented overactive/poor compliant neurogenic bladders on clean intermittent catheterization, and were resistant or non compliant to pharmacological therapy. Ten patients presented second to fourth grade concomitant monolateral/bilateral vesicoureteral reflux (VUR). All patients were incontinent despite catheterization. In the majority of patients Botulinum-A toxin was administered under general/local anesthesia by the injection of 200 IU of toxin, without exceeding the dosage of 12 IU/kg body weight, diluted in 20 cc of saline solution in 20 sites, except in the periureteral areas. Follow-up included clinical and ultrasound examination, urodynamics performed at 6, 12 and 24 weeks, and annually thereafter. Seven patients remained stable, 21 patients required a second injection after 6-9 months and 19 a third injection. VUR was corrected, when necessary, in the same session after the BT-A injection, by 1-3 cc of subureteral Deflux®. Urodynamic parameters considered were leak point pressure (LPP), leak point volume (LPV) and specific volume at 20 cm H(2)O pressure. The results were analyzed using the Wilcoxon test. All patients experienced a significant 66.45% average increase of LPV (Wilcoxon paired rank test = 7169 × 10(-10)) and a significant 118.57% average increase of SC 20 (Wilcoxon paired rank test = 2.466 × 10(-12)). The difference between preoperative and postoperative LPP resulted not significant (Wilcoxon paired rank test = 0.8858) No patient presented severe systemic complications; 38/47 patients presented slight hematuria for 2-3 days. Two

  10. A Stylistic Analysis of Break,Break,Break

    Institute of Scientific and Technical Information of China (English)

    李瑶

    2015-01-01

    Break, Break, Break is a poem by Alfred Lord Tennyson, the Poet Laureate during the Queen Victoria's reign. This exquisite little poem is wel known for the poet's grief-stricken feelings and heart-broken emotions over the premature death of his best friend, Arthur Henry Halam. Most of the previous studies on this poem focus on the emotional level to consider it as an elegy, expressing sorrow and lamentation for the death of a particular person. However, in order to have a deep understanding in general, this paper analyzes the poem based on the stylistic theory, concerning on the lexical level and the semantic level. It aims at helping the readers to cultivate a sense of appropriateness, to sharpen the understanding and appreciation of literary works and to achieve adaptation in translation.

  11. Improvement in Quality of Life Questionnaire Measures (PCOSQ) in Obese Adolescent Females with PCOS treated with Lifestyle Changes and Oral Contraceptives, with or without Metformin

    OpenAIRE

    Harris-Glocker, Miranda; Davidson, Kristin; Kochman, Lynda; Guzick, David; Hoeger, Kathleen

    2009-01-01

    We studied the effect of metformin or placebo in a lifestyle modification program (LSM) combined with oral contraceptives (OC) on quality of life parameters measured by the PCOS questionnaire (PCOSQ) in obese adolescent women with validated PCOS.

  12. Dynamical supersymmetry breaking

    International Nuclear Information System (INIS)

    Supersymmetry, and in particular, dynamical supersymmetry breaking, offers the hope of a natural solution of the gauge hierarchy problem in grand unification. I briefly review recent work on dynamical supersymmetry breaking in four-dimensional Higgs theories and its application to grand unified model building

  13. 解剖式(牙合)垫治疗青少年磨牙症的临床研究%Clinical study on anatomic occlusal pad treating bruxism in the adolescents

    Institute of Scientific and Technical Information of China (English)

    高乐; 万澎波; 王亚亚; 王智勇; 郑美红

    2011-01-01

    目的 研究下颌解剖式(牙合)垫治疗青少年夜磨牙症的临床效果.方法 选取磨牙症青少年患者56例,采用下领解剖式(牙合)垫治疗,依据一定的疗效标准追踪随访,随访3、6、12个月,检查下颌解剖式(牙合)垫,戴用情况,包括美学评价、(牙合)关系、颞下领关节症状等.结果 下颌解剖式(牙合)垫治疗磨牙症的总有效率为100%.结论 采用下颌解剖式(牙合)垫治疗青少年夜磨牙症取得良好疗效.%Objective To study the clinical effects of mandibular anatomic occlusal pad on bruxism in adolescents. Methods A total of 56 adolescents with bruxism were selected and treated with mandibular anatomic occlusal pad. According to certain standard of curative effect, the patients were followed up for 3, 6 and 12 months after treatment to test the wearing conditions, including aesthetic evaluation, occlusal relationships, and symptoms of temporomandibular joint etc. Results Total effective rate of mandibular anatomic occlusal pad treating bruxism was 100%. Conclusion Anatomic occlusal pad has a good effect in treating bruxism in adolescents.

  14. Suicide attempts by exogenous intoxication among female adolescents treated at a reference hospital in the city of Recife-PE, Brazil

    Directory of Open Access Journals (Sweden)

    Juliana Lourenço de Araújo Veras

    2011-10-01

    Full Text Available This study aimed to assess cases of self-inflicted poisoning among adolescents reported by the Toxicological Care Center of a reference hospital in Recife-PE, Brazil. The data were collected between March and May 2010 from hospital charts and structured interviews with the participants and parents/guardians. Among the 25 cases of attempted suicide registered in the period, 21 were female adolescents, who made up the sample of the present study. The adolescents were between 13 and 19 years of age. Pesticides were the most frequent toxic agent used (61.9%. The results of the present study underscore the importance of studying suicide in this population, with a focus on family relations, in order to lay the foundation for the development of prevention and treatment programs for this vulnerable group.

  15. Break the ice

    Institute of Scientific and Technical Information of China (English)

    2015-01-01

    Jacky:My sister is mad at me.She refuses(拒绝)to talk to me.What can I do to break the ice?Ella:You can buy her a little gift.Break的意思是"打破",ice是指"冰块"。冰是又冷又硬的东西,作为俗语break the ice是指"打破沉默(僵局)"。Jacky惹妹妹生气,妹妹不理他了,他能通过送小礼物break the ice吗?

  16. Adolescent development

    Science.gov (United States)

    Development - adolescent; Growth and development - adolescent ... rights and privileges. Establish and maintain satisfying relationships. Adolescents will learn to share intimacy without feeling worried ...

  17. Adolescent development

    Science.gov (United States)

    Development - adolescent; Growth and development - adolescent ... During adolescence, children develop the ability to: Understand abstract ideas. These include grasping higher math concepts, and developing moral ...

  18. Cost-Effectiveness of Extended-Release Methylphenidate in Children and Adolescents with Attention-Deficit/Hyperactivity Disorder Sub-Optimally Treated with Immediate Release Methylphenidate

    NARCIS (Netherlands)

    van der Schans, Jurjen; Kotsopoulos, Niko; Hoekstra, Pieter J.; Hak, Eelko; Postma, Maarten J.

    2015-01-01

    BACKGROUND: Attention-Deficit/Hyperactivity Disorder (ADHD) is a common psychiatric disorder in children and adolescents. Immediate-release methylphenidate (IR-MPH) is the medical treatment of first choice. The necessity to use several IR-MPH tablets per day and associated potential social stigma at

  19. Supersymmetry breaking from superstrings

    International Nuclear Information System (INIS)

    The gauge hierarchy problem is briefly reviewed and a class of effective field theories obtained from superstrings is described. These are characterized by a classical symmetry, related to the space-time duality of string theory, that is responsible for the suppression of observable supersymmetry breaking effects. At the quantum level, the symmetry is broken by anomalies that provide the seed of observable supersymmetry breaking, and an acceptably large gauge hierarchy may be generated. 26 refs

  20. Emotional well-being in children and adolescents treated with atomoxetine for attention-deficit/hyperactivity disorder: Findings from a patient, parent and physician perspective using items from the pediatric adverse event rating scale (PAERS

    Directory of Open Access Journals (Sweden)

    Dittmann Ralf W

    2008-05-01

    Full Text Available Abstract Background The objective of this analysis was to measure changes in items on the Pediatric Adverse Event Rating Scale (PAERS that relate to emotional well-being of children and adolescents with Attention-Deficit/Hyperactivity Disorder (ADHD during treatment with atomoxetine for up to 24 weeks from the perspective of the patient, the parent, and the physician. Methods Patients aged 6–17 years with ADHD were treated with atomoxetine (target dose 1.2 mg/kg/day. In the two studies on which this secondary analysis is based the PAERS was used to assess the tolerability of atomoxetine in children and adolescents. This scale has a total of 48 items. The ten items that reflect emotional well-being were selected to measure changes over time from a patient, parent, and physician perspective. Results 421 patients were treated with atomoxetine. 355 patients completed the 8-week treatment period, and 260 patients completed the 24-week treatment period. The ten items that reflect emotional well-being were grouped in five dimensions: depressed mood, self-harm, irritability/agitation, drowsiness, and euphoria. The scores of these dimensions decreased over time, both from a patient as well as from a parent and physician perspective. Only the dimension self-harm was extremely low at baseline and stayed low over time. The mean scores for the ten items depended on the rater perspective. Conclusion The emotional well-being of children and adolescents with ADHD improved in terms of depressed mood, irritability/agitation, drowsiness, and euphoria during treatment with atomoxetine for up to 24 weeks.

  1. CP breaking in lattice chiral gauge theories

    International Nuclear Information System (INIS)

    The CP symmetry is not manifestly implemented for the local and doubler-free Ginsparg-Wilson operator in lattice chiral gauge theory. We precisely identify where the effects of this CP breaking appear. We show that they appear in: (I) Overall constant phase of the fermion generating functional. (II) Overall constant coefficient of the fermion generating functional. (III) Fermion propagator appearing in external fermion lines and the propagator connected to Yukawa vertices. The first effect appears from the transformation of the path integral measure and it is absorbed into a suitable definition of the constant phase factor for each topological sector; in this sense there appears no 'CP anomaly'. The second constant arises from the explicit breaking in the action and it is absorbed by the suitable weights with which topological sectors are summed. The last one in the propagator is inherent to this formulation and cannot be avoided by a mere modification of the projection operator, for example, in the framework of the Ginsparg-Wilson operator. This breaking emerges as an (almost) contact term in the propagator when the Higgs field, which is treated perturbatively, has no vacuum expectation value. In the presence of the vacuum expectation value, however, a completely new situation arises and the breaking becomes intrinsically non-local, though this breaking may still be removed in a suitable continuum limit. This non-local CP breaking is expected to persist for a non-perturbative treatment of the Higgs coupling. (author)

  2. 中西医联合治疗青少年抑郁症疗效观察%Effect observation on treating adolescent depressive disorder in the integrative medicine

    Institute of Scientific and Technical Information of China (English)

    叶沐镕

    2013-01-01

      目的:探求中西医联合治疗青少年抑郁症的疗效是否优于单独运用西医治疗.方法:将78例青少年抑郁症患者随机分为观察组和对照组,两组各39例,观察组服用舍曲林加中药汤剂,而对照组只应用舍曲林.采用汉密尔顿抑郁量表(HAMD)评定临床疗效.结果:观察组治疗有效率为94.44%,对照组有效率为78.38%.两组治疗前 HAMD 得分无显著差异,但治疗后2周、1个月、2个月后观察组减分率显著高于对照组.结论:单用西药治疗青少年抑郁症有一定疗效,但中西医联合治疗具有起效快、疗效稳定和持续时间长的优势,更利于青少年的人格发展和身心健康.%Objective: To compare the efficacies between the integrative medicine and modern medicine alone on adolescent depression disorder, to optimize the treatment of adolescent depression. Methods:78 depressed adolescent patients were randomly divided into the treated group and the control group, 39 patients in each group. Patients in the treated group were given sertraline combined with Chinese decoction, while the control group patients took only sertraline. Hamilton Depression Rating Scale (HAMD) was applied to evaluate the clinical efficacy. Results: The total effective rate in the treated group was 94.44%, while that in the control group was only 78.38%. No significant differences were detected in HAMD score before treatment, but reduction rate in the treated group was significantly higher than that in the control group two weeks, one month, and two months after the treatment. Conclusion: Western medicine treatment only had a certain effect on adolescents’ depression, but the integrative medicine had advantages of rapid onset, stable efficacy and long duration. The integrated therapy is more conducive to the character development and physical and mental health of young people.

  3. A trial of d-cycloserine to treat the social deficit in older adolescents and young adults with autism spectrum disorders.

    Science.gov (United States)

    Urbano, Maria; Okwara, Leonore; Manser, Paul; Hartmann, Kathrin; Deutsch, Stephen I

    2015-01-01

    Autism spectrum disorders are difficult for older adolescents and young adults as impaired social communication affects the transition to adult life. d-Cycloserine, a partial glycine agonist at the N-methyl-d-aspartic acid receptor, was tested in a double-blind randomized trial in 20 older adolescents and young adults with autism spectrum disorders using two dosing strategies (50 mg daily versus 50 mg weekly) for 8 weeks with a 2-week follow-up after discontinuation. d-Cycloserine caused statistically and clinically significant improvement with no differentiation between dosing strategies on the Social Responsiveness Scale and the Aberrant Behavior Checklist before and after d-cycloserine administration. PMID:25923852

  4. New strategies to ensure good patient–physician communication when treating adolescents and young adults with cancer: the proposed model of the Milan Youth Project

    OpenAIRE

    Ferrari, Andrea

    2015-01-01

    Maria Chiara Magni,1 Laura Veneroni,1 Carlo Alfredo Clerici,2 Tullio Proserpio,3 Giovanna Sironi,1 Michela Casanova,1 Stefano Chiaravalli,1 Maura Massimino,1 Andrea Ferrari1 1Pediatric Oncology Unit, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy; 2Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy; 3Pastoral Care Unit, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy Abstract: Adolescence is a particularly complex time of life, entailing p...

  5. New strategies to ensure good patient–physician communication when treating adolescents and young adults with cancer: the proposed model of the Milan Youth Project

    OpenAIRE

    Magni MC; Veneroni L; Clerici CA; Proserpio T; Sironi G; Casanova M.; Chiaravalli S; Massimino M; Ferrari A.

    2015-01-01

    Maria Chiara Magni,1 Laura Veneroni,1 Carlo Alfredo Clerici,2 Tullio Proserpio,3 Giovanna Sironi,1 Michela Casanova,1 Stefano Chiaravalli,1 Maura Massimino,1 Andrea Ferrari1 1Pediatric Oncology Unit, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy; 2Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy; 3Pastoral Care Unit, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy Abstract: Adolescence is a particularly complex time of life, entailing p...

  6. Outcome of children and adolescents with Burkitt lymphoma and diffuse large B cell lymphoma treated with a modified NHL-BFM-90 protocol

    Institute of Scientific and Technical Information of China (English)

    孙晓非

    2014-01-01

    Objective To evaluate the efficacy of a modified NHL-BFM-90 protocol in childhood and adolescence with Burkitt lymphoma(BL)and diffuse large B-cell lymphoma(DLBCL).Methods A total of 138 de novo patients with BL and DLBCL were enrolled.All patients were stratified into low(R1),intermediate(R2)and high risk(R3)groups based on the stage,chemotherapy

  7. Break preclusion: an overview

    International Nuclear Information System (INIS)

    This paper is the result of an attempt to understand the frequently referred terms 'Break Preclusion' (BP) and 'Leak Before Break' (LBB) criteria in the safety literature and available relevant information on internet. Break Preclusion means exclusion of assumption of double ended guillotine rupture of pipelines and instead assuming leak before break which allows to use a reliable system for leak detection signal to shutdown the reactor before the pipe rupture occurs. In other words it means discovery of leak before fracture may occur in service. Pressure vessels and Piping of main steam lines are the areas of application of LBB. Early detection of leak enables shutdown of the reactor of the nuclear power plant. The information used for review are based on abstracts and/or concise form of papers available on internet. As early as in 1982 preclusion of double ended circumferential rupture of the main coolant line was attempted. Break preclusion concept, BPC and LBB both are based on high level knowledge of fracture mechanics. (author)

  8. Warped Supersymmetry Breaking

    CERN Document Server

    Burgess, C P; de Alwis, S P; Giddings, S B; Maharana, A; Quevedo, Fernando; Suruliz, K

    2008-01-01

    We address the size of supersymmetry-breaking effects within higher-dimensional settings where the observable sector resides deep within a strongly warped region, with supersymmetry breaking not necessarily localized in that region. Our particular interest is in how the supersymmetry-breaking scale seen by the observable sector depends on this warping. We obtain this dependence in two ways: by computing within the microscopic (string) theory supersymmetry-breaking masses in supermultiplets; and by investigating how warping gets encoded into masses within the low-energy 4D effective theory. We find that the lightest gravitino mode can have mass much less than the straightforward estimate from the mass shift of the unwarped zero mode. This lightest Kaluza-Klein excitation plays the role of the supersymmetric partner of the graviton and has a warped mass m_{3/2} proportional to e^A, with e^A the warp factor, and controls the size of the soft SUSY breaking terms. We formulate the conditions required for the exist...

  9. Electroweak symmetry breaking

    International Nuclear Information System (INIS)

    The Higgs mechanism is reviewed in its most general form, requiring the existence of a new symmetry-breaking force and associated particles, which need not however be Higgs bosons. The first lecture reviews the essential elements of the Higgs mechanism, which suffice to establish low energy theorems for the scattering of longitudinally polarized W and Z gauge bosons. An upper bound on the scale of the symmetry-breaking physics then follows from the low energy theorems and partial wave unitarity. The second lecture reviews particular models, with and without Higgs bosons, paying special attention to how the general features discussed in lecture 1 are realized in each model. The third lecture focuses on the experimental signals of strong WW scattering that can be observed at the SSC above 1 TeV in the WW subenergy, which will allow direct measurement of the strength of the symmetry-breaking force. 52 refs., 10 figs

  10. Differences in quantification of DNA double-strand breaks assessed by 53BP1/γH2AX focus formation assays and the comet assay in mammalian cells treated with irradiation and N-acetyl-L-cysteine

    Science.gov (United States)

    Kurashige, Tomomi; Shimamura, Mika; Nagayama, Yuji

    2016-01-01

    The biological effect of ionizing radiation (IR) on genomic DNA is thought to be either direct or indirect; the latter is mediated by IR induction of free radicals and reactive oxygen species (ROS). This study was designed to evaluate the effect of N-acetyl-L-cysteine (NAC), a well-known ROS-scavenging antioxidant, on IR induction of genotoxicity, cytotoxicity and ROS production in mammalian cells, and aimed to clarify the conflicting data in previous publications. Although we clearly demonstrate the beneficial effect of NAC on IR-induced genotoxicity and cytotoxicity (determined using the micronucleus assay and cell viability/clonogenic assays), the data on NAC's effect on DNA double-strand break (DSB) formation were inconsistent in different assays. Specifically, mitigation of IR-induced DSBs by NAC was readily detected by the neutral comet assay, but not by the γH2AX or 53BP1 focus assays. NAC is a glutathione precursor and exerts its effect after conversion to glutathione, and presumably it has its own biological activity. Assuming that the focus assay reflects the biological responses to DSBs (detection and repair), while the comet assay reflects the physical status of genomic DNA, our results indicate that the comet assay could readily detect the antioxidant effect of NAC on DSB formation. However, NAC's biological effect might affect the detection of DSB repair by the focus assays. Our data illustrate that multiple parameters should be carefully used to analyze DNA damage when studying potential candidates for radioprotective compounds. PMID:26951077

  11. Routinizing Breaking News

    DEFF Research Database (Denmark)

    Hartley, Jannie Møller

    2011-01-01

    This chapter revisits seminal theoretical categorizations of news proposed three decades earlier by US sociologist Gaye Tuchman. By exploring the definition of ”breaking news” in the contemporary online newsrooms of three Danish news organisations, the author offers us a long overdue re-theorizat...

  12. Breaking the Waves

    DEFF Research Database (Denmark)

    Christensen, Poul Rind; Kirketerp, Anne

    2006-01-01

    The paper shortly reveals the history of a small school - the KaosPilots - dedicated to educate young people to carriers as entrepreneurs. In this contribution we want to explore how the KaosPilots managed to break the waves of institutionalised concepts and practices of teaching entrepreneurship...

  13. Model Breaking Points Conceptualized

    Science.gov (United States)

    Vig, Rozy; Murray, Eileen; Star, Jon R.

    2014-01-01

    Current curriculum initiatives (e.g., National Governors Association Center for Best Practices and Council of Chief State School Officers 2010) advocate that models be used in the mathematics classroom. However, despite their apparent promise, there comes a point when models break, a point in the mathematical problem space where the model cannot,…

  14. New strategies to ensure good patient–physician communication when treating adolescents and young adults with cancer: the proposed model of the Milan Youth Project

    Directory of Open Access Journals (Sweden)

    Magni MC

    2015-08-01

    Full Text Available Maria Chiara Magni,1 Laura Veneroni,1 Carlo Alfredo Clerici,2 Tullio Proserpio,3 Giovanna Sironi,1 Michela Casanova,1 Stefano Chiaravalli,1 Maura Massimino,1 Andrea Ferrari1 1Pediatric Oncology Unit, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy; 2Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy; 3Pastoral Care Unit, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy Abstract: Adolescence is a particularly complex time of life, entailing physiological, psychological, and social changes that further the individual's cognitive, emotional, and social growth. Being diagnosed with cancer at this time can have important consequences on an individual's emotional and physical development, and adolescent and young adult cancer patients have particular medical and psychosocial needs. Patient–physician communications are important in any clinical relationship, but fundamental in the oncological sphere because their quality can affect the patient–physician relationship, the therapeutic alliance, and patient compliance. A major challenge when dealing with adolescent and young adult patients lies in striking the right balance between their need and right to understand their disease, treatment, and prognosis, and the need for them to remain hopeful and to protect their emotional sensitivity. We herein describe the activities of the Youth Project of the Istituto Nazionale Tumori in Milan, Italy in order to share a possible model of interaction with these special patients and the tactics our group has identified to help them communicate and share their thoughts. This model implies not only the involvement of a multidisciplinary team, including psychologists and spirituality experts, but also the constitution of dedicated creative activities to give patients the opportunity to express feelings they would otherwise never feel at ease putting into words. These efforts seek the goal to minimize the potentially

  15. Chiral symmetry and chiral-symmetry breaking

    Energy Technology Data Exchange (ETDEWEB)

    Peskin, M.E.

    1982-12-01

    These lectures concern the dynamics of fermions in strong interaction with gauge fields. Systems of fermions coupled by gauge forces have a very rich structure of global symmetries, which are called chiral symmetries. These lectures will focus on the realization of chiral symmetries and the causes and consequences of thier spontaneous breaking. A brief introduction to the basic formalism and concepts of chiral symmetry breaking is given, then some explicit calculations of chiral symmetry breaking in gauge theories are given, treating first parity-invariant and then chiral models. These calculations are meant to be illustrative rather than accurate; they make use of unjustified mathematical approximations which serve to make the physics more clear. Some formal constraints on chiral symmetry breaking are discussed which illuminate and extend the results of our more explicit analysis. Finally, a brief review of the phenomenological theory of chiral symmetry breaking is presented, and some applications of this theory to problems in weak-interaction physics are discussed. (WHK)

  16. Antidepressant Medications for Children and Adolescents: Information for Parents and Caregivers

    Science.gov (United States)

    ... will investigate how best to treat adolescents whose depression is resistant to the first SSRI medication they have tried. ... Adolescents with Depression Study (TADS) Treatment of SSRI-resistant Depression in Adolescents (TORDIA) PubMed: Journal Articles about Children ...

  17. Incompatibility breaking quantum channels

    International Nuclear Information System (INIS)

    A typical bipartite quantum protocol, such as EPR-steering, relies on two quantum features, entanglement of states and incompatibility of measurements. Noise can delete both of these quantum features. In this work we study the behavior of incompatibility under noisy quantum channels. The starting point for our investigation is the observation that compatible measurements cannot become incompatible by the action of any channel. We focus our attention to channels which completely destroy the incompatibility of various relevant sets of measurements. We call such channels incompatibility breaking, in analogy to the concept of entanglement breaking channels. This notion is relevant especially for the understanding of noise-robustness of the local measurement resources for steering. (paper)

  18. Breaking News as Radicalisation

    DEFF Research Database (Denmark)

    Hartley, Jannie Møller

    The aim of the paper is to make explicit how the different categories are applied in the online newsroom and thus how new categories can be seen as positioning strategies in the form of radicalisations of already existing categories. Thus field theory provides us with tools to analyse how online...... journalists are using the categorisations to create hierarchies within the journalistic field in order to position themselves as specialists in what Tuchman has called developing news, aiming and striving for what today is know as breaking news and the “exclusive scoop,” as the trademark of online journalism...... in a media environment where immediacy rules (Domingo 2008a). Following this research the primary focus of this paper is the category breaking news and Tuchmans developing news, but as they are all connected the analysis will also draw upon the other categories in Tuchmans typology. The theoretical...

  19. Dynamical Electroweak Symmetry Breaking

    Czech Academy of Sciences Publication Activity Database

    Hošek, Jiří; Smetana, Adam

    Berlin: Springer, 2014, s. 17-28. ISBN 978-3-319-07072-8 R&D Projects: GA ČR GA202/06/0734; GA MŠk LA08015; GA MŠk LA08032 Institutional support: RVO:61389005 Keywords : dynamical electroweak symmetry breaking * top-quark condensation * neutriono condensation * strong Yukawa dynamics * flavor gauge dynamics Subject RIV: BE - Theoretical Physics

  20. Predicting appointment breaking.

    Science.gov (United States)

    Bean, A G; Talaga, J

    1995-01-01

    The goal of physician referral services is to schedule appointments, but if too many patients fail to show up, the value of the service will be compromised. The authors found that appointment breaking can be predicted by the number of days to the scheduled appointment, the doctor's specialty, and the patient's age and gender. They also offer specific suggestions for modifying the marketing mix to reduce the incidence of no-shows. PMID:10142384

  1. On the symmetry breaking phenomenon

    OpenAIRE

    Birtea, Petre; Puta, Mircea; Ratiu, Tudor S.; Tudoran, Ruazvan Micu

    2006-01-01

    We investigate the problem of symmetry breaking in the framework of dynamical systems with symmetry on a smooth manifold. Two cases will be analyzed: general and Hamiltonian dynamical systems. We give sufficient conditions for symmetry breaking in both cases.

  2. Symmetry breaking. 2. ed.

    International Nuclear Information System (INIS)

    This new edition of Prof. Strocchi's well received primer on rigorous aspects of symmetry breaking presents a more detailed and thorough discussion of the mechanism of symmetry breaking in classical field theory in relation with the Noether theorem. Moreover, the link between symmetry breaking without massless Goldstone bosons in Coulomb systems and in gauge theories is made more explicit in terms of the delocalized Coulomb dynamics. Furthermore, the chapter on the Higgs mechanism has been significantly expanded with a non-perturbative treatment of the Higgs phenomenon, at the basis of the standard model of particle physics, in the local and in the Coulomb gauges. Last but not least, a subject index has been added and a number of misprints have been corrected. From the reviews of the first edition: The notion of spontaneous symmetry breaking has proven extremely valuable, the problem is that most derivations are perturbative and heuristic. Yet mathematically precise versions do exist, but are not widely known. It is precisely the aim of his book to correct this unbalance. - It is remarkable to see how much material can actually be presented in a rigorous way (incidentally, many of the results presented are due to Strocchi himself), yet this is largely ignored, the original heuristic derivations being, as a rule, more popular. - At each step he strongly emphasizes the physical meaning and motivation of the various notions introduced, a book that fills a conspicuous gap in the literature, and does it rather well. It could also be a good basis for a graduate course in mathematical physics. It can be recommended to physicists as well and, of course, for physics/mathematics libraries. J.-P. Antoine, Physicalia 28/2, 2006 Strocchi's main emphasis is on the fact that the loss of symmetric behaviour requires both the non-symmetric ground states and the infinite extension of the system. It is written in a pleasant style at a level suitable for graduate students in

  3. Breaking bad news in cancer patients

    Directory of Open Access Journals (Sweden)

    Apostolos Konstantis

    2015-01-01

    Full Text Available Objective: In a regional hospital, many patients are newly diagnosed with cancer. Breaking the bad news in these patients and their relatives is a tough task. Many doctors are not experienced in talking to patients about death or death-related diseases. In recent years, there have been great efforts to change the current situation. The aim of this study was to investigate the experience and education of medical personnel in breaking bad news in a secondary hospital. Materials and Methods: 59 doctors from General Hospital of Komotini, Greece were included in the study. All the doctors were in clinical specialties that treated cancer patients. A brief questionnaire was developed based on current guidelines such as Baile/SPIKES framework and the ABCDE mnemonic. Results: Residents are involved in delivering bad news less frequently than specialists. Only 21 doctors (35.59% had specific training on breaking bad news. 20 doctors (33.90% were aware of the available techniques and protocols on breaking bad news. 47 doctors (79.66% had a consistent plan for breaking bad news. 57 (96.61% delivered bad news in a quiet place, 53 (89.83% ensured no interruptions and enough time, 53 (89.83% used simple words and 54 (91.53% checked for understanding and did not rush through the news. 46 doctors (77.97% allowed relatives to determine patient′s knowledge about the disease. Conclusions: There were low rates of specific training in breaking bad news. However, the selected location, the physician′s speech and their plan were according to current guidelines.

  4. Asthma care for children and adolescents

    OpenAIRE

    Jonsson, Marina

    2015-01-01

    Background: Asthma is one of the most common chronic diseases among young children and adolescents. With high quality health care, most children and adolescents with asthma can live an active and normal life. Yet, many children and adolescents have uncontrolled asthma, with symptoms and exacerbations which may affect their daily life. Adolescence is a sensitive period and asthma may be difficult to treat due to poor adherence to treatment. Little is known about health care professionals’ adhe...

  5. Skin Diseases and the Adolescent

    Science.gov (United States)

    Bauer, Marjorie

    1970-01-01

    Discusses such concerns as acne, syphilis, drug abuse, and tatoos. Indicates need for physician not only to treat skin diseases but to help adolescents to accept themselves and find constructive directions. (CJ)

  6. Sport injuries in adolescents

    OpenAIRE

    Susanne Habelt; Carol Claudius Hasler; Klaus Steinbrück; Martin Majewski

    2011-01-01

    In spite of the wide range of injuries in adolescents during sports activities, there are only a few studies investigating the type and frequency of sport injuries in puberty. However, this information may help to prevent, diagnose and treat sports injuries among teens. 4468 injuries in adolescent patients were treated over a ten year period of time: 66,97% were boys and 32.88% girls. The most frequent sports injuries were football (31.13%) followed by handball (8.89%) and sports during scho...

  7. Break the Pattern!

    DEFF Research Database (Denmark)

    Hasse, Cathrine; Trentemøller, Stine

    Break the Pattern! A critical enquiry into three scientific workplace cultures: Hercules, Caretakers and Worker Bees is the third publication of the international three year long project "Understanding Puzzles in the Gendered European Map" (UPGEM). By contrasting empirical findings from academic...... workplaces in the five UPGEM-countries (Denmark, Estonia, Finland, Italy and Poland) we identify three clusters of cultural patterns in physics as culture. We call these Hercules, Caretakers and Worker Bees. We also consider the influence of national cultural historical processes on the scientific culture...

  8. Symmetries and Symmetry Breaking

    CERN Document Server

    Van Oers, W T H

    2003-01-01

    In understanding the world of matter, the introduction of symmetry principles following experimentation or using the predictive power of symmetry principles to guide experimentation is most profound. The conservation of energy, linear momentum, angular momentum, charge, and CPT involve fundamental symmetries. All other conservation laws are valid within a restricted subspace of the four interactions: the strong, the electromagnetic, the weak, and the gravitational interaction. In this paper comments are made regarding parity violation in hadronic systems, charge symmetry breaking in two nucleon and few nucleon systems, and time-reversal-invariance in hadronic systems.

  9. Breaking the Silence

    Institute of Scientific and Technical Information of China (English)

    1998-01-01

    Many women who suffer from vaginitis have kept silent about their illness because they think it is shameful to have such a disease. The International Women’s Health Coalition (IWHC) has publicized the problem, referring to it as a "culture of silence"inherited from traditional thinking. The coalition has made attempts to improve women’s health conditions by changing people’s misconceptions about the disease. In 1997, under a grant from the American Ford Foundation, the Sichuan Provincial Women’s Federation carried out a study on women’s repro-ductive health, aimed at "breaking the silence."

  10. Efficacy and Safety of Botulinum Toxin A for Treating Bladder Hyperactivity in Children and Adolescents with Neuropathic Bladder Secondary to Myelomeningocele

    OpenAIRE

    Marte, Antonio; Borrelli, Micaela; Prezioso, Maurizio; Pintozzi, Lucia; Parmeggiani, Pio

    2013-01-01

    We verified the efficacy and safety of botulinum toxin A (BTX-A) in treating bladder overactivity in children with neurogenic bladder (NB) secondary to myelomeningocele (MMC). Forty-seven patients (22, females; 25, males; age range, 5–17 years; mean age, 10.7 years) with poorly compliant/overactive neurogenic bladder on clean intermittent catheterization (CIC) and resistance or noncompliant to anticholinergics were injected with 200 IU of BTX-A intradetrusor. All patients experienced a signif...

  11. Spontaneous breaking of supersymmetry

    Energy Technology Data Exchange (ETDEWEB)

    Zumino, B.

    1981-12-01

    There has been recently a revival of interest in supersymmetric gauge theories, stimulated by the hope that supersymmetry might help in clarifying some of the questions which remain unanswered in the so called Grand Unified Theories and in particular the gauge hierarchy problem. In a Grand Unified Theory one has two widely different mass scales: the unification mass M approx. = 10/sup 15/GeV at which the unification group (e.g. SU(5)) breaks down to SU(3) x SU(2) x U(1) and the mass ..mu.. approx. = 100 GeV at which SU(2) x U(1) is broken down to the U(1) of electromagnetism. There is at present no theoretical understanding of the extreme smallness of the ratio ..mu../M of these two numbers. This is the gauge hierarchy problem. This lecture attempts to review the various mechanisms for spontaneous supersymmetry breaking in gauge theories. Most of the discussions are concerned with the tree approximation, but what is presently known about radiative correction is also reviewed.

  12. Examination of the adolescent patient.

    Science.gov (United States)

    Hampton, H L

    2000-03-01

    Adolescent patients need knowledge and motivation to practice a healthy lifestyle. The provider of adolescent health care is uniquely qualified to provide factual health information and practical advice. Enlisting parental support for confidential adolescent health services usually is not problematic when parents and health care providers share common goals and responsibility. The health care provider must develop rapport to foster high-risk health behavior disclosure and must promote health messages that are stronger than those received from peers, television, movies, and magazines. Adolescents who elect to abstain from sexual activity need as much support as sexually active patients. Depression, substance abuse, and eating disorders must be recognized and treated. Preventative health care services for adolescents can be optimized when office staff understand the special needs of these young women. The physician's concerns regarding the health of adolescent patients will be welcomed by patients, their parents, and the community. PMID:10693179

  13. Perspectives of Adolescents with Disabilities on Summer Employment and Community Experiences

    Science.gov (United States)

    Trainor, Audrey A.; Carter, Erik W.; Swedeen, Beth; Owens, Laura; Cole, Odessa; Smith, Shane

    2011-01-01

    Although summer represents an opportune time for adolescents to garner employment and community experiences that may further long-term transition goals, little is known about the expectations and needs of adolescents with disabilities during this break in the academic school year. In this article, the authors explore adolescents' perceptions about…

  14. Violent breaking wave impacts

    DEFF Research Database (Denmark)

    Bredmose, Henrik; Peregrine, D.H.; Bullock, G.N.

    2009-01-01

    When an ocean wave breaks against a steep-fronted breakwater, sea wall or a similar marine structure, its impact on the structure can be very violent. This paper describes the theoretical studies that, together with field and laboratory investigations, have been carried out in order to gain a...... better understanding of the processes involved. The wave's approach towards a structure is modelled with classical irrotational flow to obtain the different types of impact profiles that may or may not lead to air entrapment. The subsequent impact is modelled with a novel compressible-flow model for a...... homogeneous mixture of incompressible liquid and ideal gas. This enables a numerical description of both trapped air pockets and the propagation of pressure shock waves through the aerated water. An exact Riemann solver is developed to permit a finite-volume solution to the flow model with smallest possible...

  15. Electroweak breaking in supersymmetric models

    CERN Document Server

    Ibáñez, L E

    1992-01-01

    We discuss the mechanism for electroweak symmetry breaking in supersymmetric versions of the standard model. After briefly reviewing the possible sources of supersymmetry breaking, we show how the required pattern of symmetry breaking can automatically result from the structure of quantum corrections in the theory. We demonstrate that this radiative breaking mechanism works well for a heavy top quark and can be combined in unified versions of the theory with excellent predictions for the running couplings of the model. (To be published in ``Perspectives in Higgs Physics'', G. Kane editor.)

  16. Break location effects on PWR small break LOCA phenomena

    International Nuclear Information System (INIS)

    The report presents experimental results of a small lower plenum break test of SB-PV-01 conducted at the large-Scale Test Facility (LSTF) of the Rig-of-Safety Assessment (ROSA)-IV program. This test simulates a loss-of-coolant accident (LOCA) caused by instrument tubes break (break area corresponds to 0.5% of the cold leg flow area) in a Westinghouse-type pressurized water reactor (PWR) assuming both manual actuation for all of the high pressure injection (HPI) systems and failure of the auxiliary feedwater systems. The report clarifies long-term system responses, especially the core cooling conditions related to the primary mass inventory. Also it clarifies break location effects on small break LOCA phenomena by comparing other five similar LOCA tests with break locations at cold leg, hot leg, upper head, pressurizer top (TMI-type) and SG U-tubes. It is coucluded that the lower plenum break is the severest on core heatup due to the highest break flow rate and the least primary mass recovery after the ECCS among the six tests. (author)

  17. Severe Class II Division 1 malocclusion in an adolescent patient, treated with a novel sagittal-guidance Twin-block appliance.

    Science.gov (United States)

    Li, Peilun; Feng, Jing; Shen, Gang; Zhao, Ning

    2016-07-01

    Class II malocclusion is a challenging anomaly in orthodontic practice. Various types of functional appliances are used to correct Class II skeletal and occlusal disharmonies in growing patients, including the Twin-block. We used a modified sagittal-guidance Twin-block appliance combined with a fixed appliance and microimplant anchorage to treat a 13-year-old Chinese boy with a severe skeletal Class II malocclusion and mandibular retrognathia. Normal overjet and a Class I molar relationship were achieved because of the advancement of mandibular development, the restriction of maxillary growth, and dentoalveolar modifications in both the maxilla and the mandible. Favorable skeletal, dental, and soft tissue relationships were accomplished after 24 months of treatment. After 2 years of retention, the results remained stable. PMID:27364217

  18. Fetal cerebral ventricular atria width of 8-10mm: A possible prenatal risk factor for adolescent treated Attention Deficit Hyperactivity Disorder (ADHD).

    Science.gov (United States)

    Kivilevitch, Zvi; Gabis, Lidia V; Katorza, Eldad; Achiron, Reuven

    2016-01-01

    The purpose of our research was to study the in-utero and long term post-natal outcome of fetal isolated cerebral ventricular atria width between 8 and 10mm. We conducted a retrospective, observational, case-control study, of low risk pregnant women, between 1993 and 2001. One hundred and forty one fetuses with isolated cerebral ventricular atria width between 8 and 10mm, corresponding to 2-4 standard deviations above the mean, and 309 controls, with atrial width below this level, were included for the analysis. Clinical data concerning pre and post-natal outcome was retrieved from computerized medical records. Matching of cases with controls was based on age, with a ratio of 2-3 controls per case. Statistical analysis included: T-test, Chi-Square, and Multiple Logistic Regression analysis. The study group was characterized by a predominance of male gender, left side involvement, and higher birth weight, compared to the control group. Long term post-natal follow-up at a mean age of 12.7 years (±1.9) demonstrated an adjusted odds ratio of 2.589 (95% CI 1.415-4.737, p=0.001), being diagnosed as Attention Deficit Hyperactivity Disorder (ADHD), and treated by Methylphenidate (Ritalin(®)), during childhood, compared to the control group (23.6% and 10.0% respectively) (p=0.001). Cerebral atria width was an independent factor, controlled for the only two significant variants between groups, gender and weight over 90th centile. In conclusions, our preliminary results show that fetuses with prenatal finding of isolated cerebral ventricular atria width between 8 and 10mm are more likely of being diagnosed and treated as ADHD during childhood. PMID:26672679

  19. 青少年脊柱侧凸症的支具治疗:应用与评估%Adolescent scoliosis treated with braces: application and evaluation

    Institute of Scientific and Technical Information of China (English)

    钱雪华; 孙鹏; 施杞

    2005-01-01

    目的:探讨青少年脊柱侧凸症的非手术疗法之一支具治疗的应用历史,疗效评估及其副作用.资料来源:应用计算机检索Medline 1970-01/2003-12和Embase1970-01/2004-04有关青少年脊柱侧凸症支具治疗的文章,检索词为"Adolescent idiopathic scoliosis,brace,review",并限定文章语言种类为English.资料选择:根据综述描述及引用文献,选取使用支具治疗青少年脊柱侧凸症的研究报道.纳入标准:符合随机临床试验,有正常组对照或/和支具类型之间的对比评估分析及10个月以上的随访研究.排除标准:明显不符合临床随机实验要求的文章.资料提炼:共检索到42篇支具治疗青少年脊柱侧凸症的综述文献,从中筛选出24篇文献,分析评估青少年脊柱侧凸症的支具应用,排除的文献包括同一内容的实验研究及未做随访的研究文章.资料综合:24个实验包括5 432例患者,均采取各种支具治疗青少年脊柱侧凸症.支具类型包括Boston、Charleston、胸腰骶支具和Milwaukee等.目前对支具的有效性及支具选择方面仍存在不同意见.不恰当的支具治疗可能引起多种并发症,如皮肤溃疡、心理障碍、背痛、胸廓畸形及影响呼吸功能障碍等.结论:虽然对支具使用和效果评估存在不同意见,但一般认为规范化的早期支具治疗可以有限的控制青少年脊柱侧凸症的畸形进展.

  20. Frequent marijuana use in adolescence.

    Science.gov (United States)

    Schwartz, R H

    1985-01-01

    Although the adolescent's first use of marijuana is rarely pleasant, peer pressure often causes continued experimenting and a search for the euphoric "high." Preoccupation with use of the drug leads to mood changes, withdrawal, academic underachievement and confusion. Family members may refuse to admit that a drug problem exists and may subsequently develop dependency problems of their own. By assuming responsibility for the adolescent's drug problem, a parent enables the drug use to continue. To break this cycle, family members must seek guidance from a rehabilitation professional. PMID:3871295

  1. The incidence of caries and white spot lesions in orthodontically treated adolescents with a comprehensive caries prophylactic regimen--a prospective study.

    Science.gov (United States)

    Hadler-Olsen, Sigurd; Sandvik, Kristin; El-Agroudi, Mohammad A; Øgaard, Bjørn

    2012-10-01

    The aim of the study was to assess the effect of a comprehensive prophylactic regimen in reducing the incidence of white spot lesions (WSL) and caries during orthodontic treatment. Eighty consecutive patients, scheduled for fixed appliance treatment in both jaws were compared with a non-orthodontic matched-control group. The oral hygiene regimen consisted of brushing two to three times daily, flossing, fluoride rinse, and plaque disclosing tablets. Patients were requested to avoid carbonated soft drinks/acidic juices and candies. The WSL index of Gorelick et al. (Gorelick L, Geiger A M, Gwinnett A J 1982 Incidence of white spot formation after bonding and banding. American Journal of Orthodontics 81: 93-98) was used. Caries were scored according to Amarante et al. (Amarante E, Raadal M, Espelid I 1998 Impact of diagnostic criteria on the prevalence of dental caries in Norwegian children aged 5, 12 and 18 years. Community Dental Oral Epidemiology 26: 87-94). We collected data from all finished cases. It comprised 40 subjects in the orthodontic group (mean age: 13.6 years, range: 12-16 years) and 40 matched controls. The average treatment time was 18 months (range: 9-25 months). The mean increase in WSL index in the orthodontic group was 1.9 and 0.4 in the control group (P = 0.001). The mean increase in dentine caries was 0.5 lesions and 0.7 lesions in the in the orthodontic group and control group, respectively (P = 0.62). Twenty-three per cent of treated patients showed good compliance, 68 per cent moderate compliance, and 9 per cent poor compliance. The mean increase in WSL was 1.0, 1.4, and 3.3 in the good, moderate, and poor compliance group, respectively (P = 0.155). Orthodontically treated patients have significantly higher risk for developing WSL than untreated patients, while there is no difference with respect to development of new dentinal caries lesions. This study showed that a possible relationship between compliance and WSL development existed. PMID

  2. R-parity breaking phenomenology

    International Nuclear Information System (INIS)

    We review various features of the R-parity breaking phenomenology, with particular attention to the low energy observables, and to the patterns of the R-parity breaking interactions that arise in Grand Unified models. (author). 22 refs, 1 fig., 3 tabs

  3. On partially entanglement breaking channels

    OpenAIRE

    Chruściński, Dariusz; Kossakowski, Andrzej

    2005-01-01

    Using well known duality between quantum maps and states of composite systems we introduce the notion of Schmidt number of a quantum channel. It enables one to define classes of quantum channels which partially break quantum entanglement. These classes generalize the well known class of entanglement breaking channels.

  4. Entanglement–breaking indices

    International Nuclear Information System (INIS)

    We study a set of new functionals (called entanglement–breaking indices) which characterize how many local iterations of a given (local) quantum channel are needed in order to completely destroy the entanglement between the system of interest over which the transformation is defined and an external ancilla. The possibility of contrasting the noisy effects introduced by the channel iterations via the action of intermediate (filtering) transformations is analyzed. We provide some examples in which our functionals can be exactly calculated. The differences between unitary and non-unitary filtering operations are analyzed showing that, at least for systems of dimension d larger than or equal to 3, the non-unitary choice is preferable (the gap between the performances of the two cases being divergent in some cases). For d = 2 (qubit case), on the contrary, no evidences of the presence of such gap is revealed: we conjecture that for this special case unitary filtering transformations are optimal. The scenario in which more general filtering protocols are allowed is also discussed in some detail. The case of a depolarizing noise acting on a two–qubit system is exactly solved in a general case

  5. Breaking the silence

    DEFF Research Database (Denmark)

    Konradsen, Hanne; Kirkevold, Marit; McCallin, Antoinette;

    2012-01-01

    Little is known about the psychosocial effects of facial disfigurement. We present the results of a qualitative study following 15 patients who had been surgically treated for head, neck, or eye cancer over the course of their first postoperative year. Taped nurse-patient conversations and...... disfigured person to a person with a disfigurement. The model explains the process of adjustment and demonstrates various elements that could be used in interventions targeting patients who experience psychosocial problems....

  6. Spontaneous symmetry breaking in QCD

    International Nuclear Information System (INIS)

    We study dynamical chiral symmetry breaking in QCD by the use of the generalized Hartree-Fock method. The low energy quark mass is calculated to the second order of diagrammatic expansion around shifted perturbative vacuum where quarks are massive. We show that the low energy mass is finite and renormalization group invariant. We find that the finite mass gap emerges as the solutions of gap equation and stationarity condition, thereby breaking the chiral symmetry. We also discuss the possibility that the breaking solution may exist up to all orders. (author)

  7. The symmetry breaking phenomenon in anharmonic oscillator model

    CERN Document Server

    Mastine, Antonio Carlos; Natti, Erica Regina Takano

    2010-01-01

    In this article a non-perturbative time-dependent technique is used to treat the initial value problem, in Quantum Mechanics context, for a non-equilibrium self-interacting fermionic system in the presence of an external magnetic field. Particularly, in mean-field regime, we study the dynamical symmetry breaking phenomenon, identifying the physical processes associated.

  8. Break! On the unpleasant, the marginal, the taboo, and the controversial in Norwegian museums

    OpenAIRE

    Liv Ramskjaer

    2014-01-01

    This paper explores the programme entitled Break, which was launched within a grouping of Norwegian museums in 2003. Break emerged in the context of a more critical approach to museum practice and their ways of dealing with controversial pasts in the wake of the new museology. A central goal for Break has been to promote a shift from the presentation of conventionally treated narratives in order to focus on areas that are marginal, hidden, contested and regarded as unpleasant. The programme h...

  9. Adolescent Vaccination

    OpenAIRE

    Mustafa Hacımustafaoğlu

    2008-01-01

    Adolescent period usually are omitted regarding the vaccination and the other health evaluations, in our country. Adolescent period is usually considered as between the ages of 8-18 years. During this period, it is important to evaluate routine adolescent examination as well as vaccination status.Childhood (0-18 years) vaccination can be considered in three stages; infantil period vaccinations (

  10. Developmental hip dysplasia in adolescence

    Directory of Open Access Journals (Sweden)

    Vukašinović Zoran

    2009-01-01

    Full Text Available The authors define adolescence and developmental dysplasia of the hip (DDH. Special attention is paid to pathological findings characteristic of DDH in adolescence (unrecognized and untreated DDH; treated DDH, but non-terminated treatment; DDH diagnosed with delay, inadequately treated, with complications. The authors emphasise that DDH treatment has to be successfully terminated well before the adolescence; possibilities are explained on management modes at the time of adolescence, and possible persons guilty for the persistence of later hip problems are indicated. Based on the authors' experience and having in mind all surgical possibilities for the treatment (pelvic osteotomies, femoral osteotomies, trochanteroplasties, leg length equalization procedures the authors propose treatment protocols. The intention is to provide better treatment results and to prevent secondary hip arthrosis. Furthermore, how to improve the struggle against DDH is suggested.

  11. Topcolor breaking through boundary conditions

    International Nuclear Information System (INIS)

    The nontrivial boundary conditions (BC's) for the topcolor breaking are investigated in the context of the TeV-scale extra dimension scenario. In the gauge symmetry breaking mechanism via the BC's we do not need to incorporate a dynamical mechanism for the topcolor breaking into the model. Moreover, the topcolor breaking can be realized without introducing explicitly a (composite) scalar field. We present a six dimensional model where the top and bottom quarks in the bulk have the topcolor charge while the other quarks in the bulk do not. We also put the electroweak gauge interaction in the six dimensional bulk. The bottom quark condensation is naturally suppressed owing to the powerlike running of the bulk U(1)Y interaction, so that only the top condensation is expected to take place. We explore such a possibility based on the ladder Schwinger-Dyson equation and show the cutoff to make the model viable

  12. Supersymmetry Breaking in Warped Geometry

    OpenAIRE

    Choi, Kiwoon; Kim, Do Young; Kim, Ian-Woo; Kobayashi, Tatsuo

    2003-01-01

    We examine the soft supersymmetry breaking parameters in supersymmetric theories on a slice of AdS_5 which generate the hierarchical Yukawa couplings by dynamically localizing the bulk matter fields in extra dimension. Such models can be regarded as the AdS dual of the recently studied 4-dimensional models which contain a supersymmetric CFT to generate the hierarchical Yukawa couplings. In such models, if supersymmetry breaking is mediated by the bulk radion superfield and/or some brane chira...

  13. Group Counseling and Psychotherapy with Adolescents.

    Science.gov (United States)

    MacLennan, Beryce W.; Felsenfeld, Naomi

    Intended as an aid in conceptualizing group programs for adolescents and as a basic text on group methods, the book examines the goals and processes of socialization and rehabilitation. Areas treated include the group as an agent of change, the adolescent and his culture, general considerations in group counseling and group psychotherapy, process…

  14. Adolescent Victims of Abuse: A Treatment Model.

    Science.gov (United States)

    Anderson-Merchant, Darlene

    This paper presents a theory and model for treating adolescent victims of physical and sexual abuse and neglect. The theory examines issues related to abuse or neglect and the effect that an abusive history has on adolescent development. Specific issues noted are depression, anger, low self-esteem, self-shame, lack of trust, a sense of…

  15. Anchor Points Reactive Potential for Bond-Breaking Reactions.

    Science.gov (United States)

    Yang, Ke R; Xu, Xuefei; Truhlar, Donald G

    2014-03-11

    We present a new method for fitting potential energy surfaces in molecular-mechanics-like internal coordinates based on data from electronic structure calculations. The method should be applicable to chemical reactions involving either bond dissociation or isomerization and is illustrated here for bond dissociation, in particular the breaking of an O-H bond in methanol and the breaking of an N-H bond in dimethylamine. As compared to previously available systematic methods for fitting global potential energy surfaces, it extends the maximum size of the system than can be treated by at least an order of magnitude. PMID:26580172

  16. Using Music Techniques To Treat Adolescent Depression.

    Science.gov (United States)

    Hendricks, C. Bret; Robinson, Beth; Bradley, Loretta J.; Davis, Kenneth

    1999-01-01

    Discusses a school-based therapy program using music for teenagers (N=19) who demonstrated depressive symptoms. Pre- and post-testing indicated a significant decrease in depressive symptoms. Offers recommendations for further research. (Author/MKA)

  17. Sexual Issues in Treating Trauma Survivors

    OpenAIRE

    Zoldbrod, Aline P.

    2014-01-01

    The effect of interpersonal trauma on sexuality can be profound. The field of sexual trauma is complex empirically and clinically, with contradictory theories and conflicting data. Research definitions and treatment protocols for child sexual abuse are very imprecise. There are no firm, empirically proven guidelines for treating men and women who have been sexually abused as children or adolescents. Overt sexual abuse (OSA) in children and adolescents is defined here as molestation, rape, or ...

  18. Acute and subacute dermal toxicity of Break-Free CLP: a weapons cleaning and maintenance compound.

    Science.gov (United States)

    Arfsten, D P; Johnson, E W; Thitoff, A R; Jung, A E; Still, K R; Brinkley, W W; Schaeffer, D J; Jederberg, W W; Bobb, A J

    2005-01-01

    Break-Free CLP((R)) is a commercial cleaning, lubricating and preserving compound used in both the military and civilian sectors for maintenance of small- and large-caliber weapons. Like many commercial mixtures, there is very little information available on the toxicity of Break-Free CLP. Studies were conducted to characterize the biological effects of single or repeat dermal application of Break-Free CLP to the clipped backs of CD-1 mice. Break-Free CLP was applied neat, 50 microl three times of week for up to 2 weeks. Foci of epithelial ulceration were observed in skin sections from 22% of Break-Free CLP-treated animals in conjunction with markedly thickened epithelium suggesting that robust epithelial regeneration was occurring in these animals. Skin histopathology of Break-Free CLP-treated animals closely matched the histopathology from mice treated repeatedly with 2% croton oil in acetone (dermal irritation positive control). Serum alkaline phosphatase activity was significantly (P croton oil or 7,12-dimethylbenz[a]anthracene (DMBA) compared with negative and vehicle control mice. Skin nitric oxide (NO) levels were not significantly elevated for mice treated with Break-Free CLP but were significantly elevated for mice treated with dermal irritation positive control compound DMBA. The cumulative skin changes in Break-Free CLP-treated animals support conducting a subchronic dermal application study. The observed decreases in serum alkaline phosphatase activity suggest that future studies should include the liver and bone as possible target organs. Additionally, dermal penetration studies could provide key health risk assessment information for characterizing the potential health risks associated with chronic dermal exposure to Break-Free CLP. PMID:16025432

  19. Hypnoimmunotherapy in an adolescent

    International Nuclear Information System (INIS)

    The case report of an adolescent who visited the consulting room for presenting alopecia since 3 years ago, after the divorce of her parents is presented. Hypnosis was applied with imaging procedures such as the autoscopy and the immunostimulating therapy of the cellular immunity. The typical lesions of alopecia disappeared, so the patient's improvement was achieved, as well as a remarkable reduction of the treatment period. The use of the combined hypnoimmunotherapy is recommended to treat appropriately this type of dermatopathy

  20. Symmetry breaking in molecular ferroelectrics.

    Science.gov (United States)

    Shi, Ping-Ping; Tang, Yuan-Yuan; Li, Peng-Fei; Liao, Wei-Qiang; Wang, Zhong-Xia; Ye, Qiong; Xiong, Ren-Gen

    2016-07-11

    Ferroelectrics are inseparable from symmetry breaking. Accompanying the paraelectric-to-ferroelectric phase transition, the paraelectric phase adopting one of the 32 crystallographic point groups is broken into subgroups belonging to one of the 10 ferroelectric point groups, i.e. C1, C2, C1h, C2v, C4, C4v, C3, C3v, C6 and C6v. The symmetry breaking is captured by the order parameter known as spontaneous polarization, whose switching under an external electric field results in a typical ferroelectric hysteresis loop. In addition, the responses of spontaneous polarization to other external excitations are related to a number of physical effects such as second-harmonic generation, piezoelectricity, pyroelectricity and dielectric properties. Based on these, this review summarizes recent developments in molecular ferroelectrics since 2011 and focuses on the relationship between symmetry breaking and ferroelectricity, offering ideas for exploring high-performance molecular ferroelectrics. PMID:27051889

  1. One-Dimensional Horizontal Boussinesq Model Enhanced for Non-Breaking and Breaking Waves

    Institute of Scientific and Technical Information of China (English)

    DONG Guo-hai; MA Xiao-zhou; TENG Bin

    2008-01-01

    Based on a set of fully nonlinear Boussinesq equations up to the order of O(μ2, ε3μ2) (where ε is the ratio of wave amplitude to water depth and μ is the ratio of water depth to wave length) a numerical wave model is formulated. The model's linear dispersion is acceptably accurate to μ≌1.0, which is confirmed by comparisons between the simulated and measured time series of the regular waves propagating on a submerged bar. The moving shoreline is treated numerically by replacing the solid beach with a permeable beach. Run-up of nonbreaking waves is verified against the analytical solution for nonlinear shallow water waves. The inclusion of wave breaking is fulfilled by introducing an eddy term in the momentum equation to serve as the breaking wave force term to dissipate wave energy in the surf zone. The model is applied to cross-shore motions of regular waves including various types of breaking on plane sloping beaches. Comparisons of the model test results comprising spatial distribution of wave height and mean water level with experimental data are presented.

  2. Psychopathology in adolescent children of physicians.

    OpenAIRE

    Stein, B A; Leventhal, S. E.

    1984-01-01

    The clinical records of 27 adolescent children of physicians who were treated in a psychiatric unit for adolescents were studied. Most of the children had been referred by their physician fathers for evaluation of conduct or mood disorders. These referrals were often the focus of family distress. There appeared to be no typical syndrome presented by physicians' children. Those treating such patients should be especially sensitive to the possibility that parental denial will increase the patie...

  3. Breaks in plasmid DNA strand induced by laser radiation at a wavelength of 193 nm

    International Nuclear Information System (INIS)

    DNA of plasmid pB322 irradiated with laser at a wavelength of 193 nm was treated with an extract containing proteins from E.coli K12 AB1157 (wild-type). The enzymes were found to produce single- and double-strand DNA breaks, which was interpreted as a transformation of a portion of cyclobutane pyrimidine dimers and (6-4) photoproducts into nonrepairable single-strand DNA breaks. The products resulted from ionization of DNA, in particular, single-strand breaks, transform to double-strand breaks. A comparison of these data with the data on survival of plasmid upon transformation of E.coli K12 AB1157 enables one to assess the biological significance of single- and double-strand breaks. The inactivation of the plasmid is mainly determined by the number of directly formed laser-induced single-strand breaks. 26 refs.; 2 figs

  4. Give me a better break: Choosing workday break activities to maximize resource recovery.

    Science.gov (United States)

    Hunter, Emily M; Wu, Cindy

    2016-02-01

    Surprisingly little research investigates employee breaks at work, and even less research provides prescriptive suggestions for better workday breaks in terms of when, where, and how break activities are most beneficial. Based on the effort-recovery model and using experience sampling methodology, we examined the characteristics of employee workday breaks with 95 employees across 5 workdays. In addition, we examined resources as a mediator between break characteristics and well-being. Multilevel analysis results indicated that activities that were preferred and earlier in the work shift related to more resource recovery following the break. We also found that resources mediated the influence of preferred break activities and time of break on health symptoms and that resource recovery benefited person-level outcomes of emotional exhaustion, job satisfaction, and organizational citizenship behavior. Finally, break length interacted with the number of breaks per day such that longer breaks and frequent short breaks were associated with more resources than infrequent short breaks. PMID:26375961

  5. An Analysis of Break,Break,Break Based on the Stylistic Theory

    Institute of Scientific and Technical Information of China (English)

    李瑶

    2014-01-01

    Break,Break,Break is a poem by Alfred Lord Tennyson, the Poet Laureate during the Queen Victoria's reign. This exquisite little poem is wel known for the poet’s grief-stricken feelings and heart-broken emotions over the premature death of his best friend, Arthur Henry Hal am. Most of the previous studies on this poem focus on the emotional level to consider it as an elegy, expressing sorrow and lamentation for the death of a particular person. However, in order to have a deep understanding in general, this paper analyzes the poem based on the stylistic theory, concerning on the phonological level and the grammatical level. It aims at helping the readers to cultivate a sense of appropriateness, to sharpen the understanding and appreciation of literary works and to achieve adaptation in translation.

  6. Accessibility of adolescent health services

    Directory of Open Access Journals (Sweden)

    S Richter

    2000-09-01

    Full Text Available Adolescents represent a large proportion of the population. As they mature and become sexually active, they face more serious health risks. Most face these risks with too little factual information, too little guidance about sexual responsibility and multiple barriers to accessing health care. A typical descriptive and explanatory design was used to determine what the characteristics of an accessible adolescent health service should be. Important results and conclusions that were reached indicate that the adolescent want a medical doctor and a registered nurse to be part of the health team treating them and they want to be served in the language of their choice. Family planning, treatment of sexually transmitted diseases and psychiatric services for the prevention of suicide are services that should be included in an adolescent accessible health service. The provision of health education concerning sexual transmitted diseases and AIDS is a necessity. The service should be available thought out the week (included Saturdays and within easy reach. It is recommended that minor changes in existing services be made, that will contribute towards making a health delivery service an adolescent accessible service. An adolescent accessible health service can in turn make a real contribution to the community’s efforts to improve the health of its adolescents and can prove to be a rewarding professional experience to the health worker.

  7. Liquid-Bridge Breaking Limits

    Science.gov (United States)

    Macner, Ashley; Steen, Paul

    2011-11-01

    Wet adhesion by liquid bridges in large arrays shows promise for use in lightweight, controllable on-demand devices. Applications include grab/release of wafer substrates, transport of micron-sized tiles for use in 3D printing and micro-dosing of personalized pharmaceutical drugs. By wetting and spreading, a drop can form a bridge and thereby ``grab'' a nearby solid substrate. By volume decrease or extension, the bridge can break. The breaking limit corresponds to bridge instability which can be predicted, knowing the static mechanical response of the bridge. Mechanical behaviors include force-volume (FV), pressure-volume (pV) and force-length (FL) responses. Instability crucially depends on the mode of failure - failure under constant-force or constant length are typical cases. We study single bridge equilibria for their breaking limits. FV diagrams for the pin-pin equal and pin-pin unequal radii boundary conditions for different bridge heights are measured in the laboratory. The FL response in the case of pin-pin equal radii is also measured. Results are compared to predictions of static theory. Static results are then used to compare to dynamical sequences where volume is driven quasistatically by syringe or an electro-osmotic pump. As the breaking limit is approached, the shape deformation accelerates leading to non-equilibrium shapes not captured by the static analysis.

  8. Strong coupling electroweak symmetry breaking

    Energy Technology Data Exchange (ETDEWEB)

    Barklow, T.L. [Stanford Linear Accelerator Center, Menlo Park, CA (United States); Burdman, G. [Univ. of Wisconsin, Madison, WI (United States). Dept. of Physics; Chivukula, R.S. [Boston Univ., MA (United States). Dept. of Physics

    1997-04-01

    The authors review models of electroweak symmetry breaking due to new strong interactions at the TeV energy scale and discuss the prospects for their experimental tests. They emphasize the direct observation of the new interactions through high-energy scattering of vector bosons. They also discuss indirect probes of the new interactions and exotic particles predicted by specific theoretical models.

  9. Sediment transport under breaking waves

    DEFF Research Database (Denmark)

    Christensen, Erik Damgaard; Hjelmager Jensen, Jacob; Mayer, Stefan

    2000-01-01

    generated at the surface where the wave breaks as well as the turbulence generated near the bed due to the wave-motion and the undertow. In general, the levels of turbulent kinetic energy are found to be higher than experiments show. This results in an over prediction of the sediment transport. Nevertheless...

  10. Oil prices: Breaks and trends

    International Nuclear Information System (INIS)

    This paper contributes to the literature of the stationarity of financial time series and the literature on oil and macroeconomics in several ways. First, it uses Kejriwal and Perron (2010) sequential procedure to endogenously determine multiple structural changes in real oil prices without facing the circular testing problem between structural changes and stationary assumptions of previous tests. Second, it performs a diagnostic check to detect the significance and magnitude of the potential breaks. Third, it uses the above information to test for the existence of stochastic trends in real oil prices, and fourth, it speculates about possible explanations for the break dates found in order to encourage further work and discussions. The exercise uses monthly data from January 1861 to August 2011. - Highlights: ► The model endogenously determine multiple structural changes in real oil prices. ► The methods used does not face the circular testing problem. ► It also detect the significance and magnitude of the breaks detected. ► It tests for the existence of stochastic trends. ► It explains the reasons for the break dates found

  11. Instantons and chiral symmetry breaking

    International Nuclear Information System (INIS)

    A detailed investigation of chiral symmetry breaking due to instanton dynamics is carried out, within the framework of the dilute gas approximation, for quarks in both the fundamental and adjoint representations of SU(2). The momentum dependence of the dynamical mass is found to be very similar in each representation. (orig.)

  12. Code breaking in the pacific

    CERN Document Server

    Donovan, Peter

    2014-01-01

    Covers the historical context and the evolution of the technically complex Allied Signals Intelligence (Sigint) activity against Japan from 1920 to 1945 Describes, explains and analyzes the code breaking techniques developed during the war in the Pacific Exposes the blunders (in code construction and use) made by the Japanese Navy that led to significant US Naval victories

  13. How do accretion discs break?

    Science.gov (United States)

    Dogan, Suzan

    2016-07-01

    Accretion discs are common in binary systems, and they are often found to be misaligned with respect to the binary orbit. The gravitational torque from a companion induces nodal precession in misaligned disc orbits. In this study, we first calculate whether this precession is strong enough to overcome the internal disc torques communicating angular momentum. We compare the disc precession torque with the disc viscous torque to determine whether the disc should warp or break. For typical parameters precession wins: the disc breaks into distinct planes that precess effectively independently. To check our analytical findings, we perform 3D hydrodynamical numerical simulations using the PHANTOM smoothed particle hydrodynamics code, and confirm that disc breaking is widespread and enhances accretion on to the central object. For some inclinations, the disc goes through strong Kozai cycles. Disc breaking promotes markedly enhanced and variable accretion and potentially produces high-energy particles or radiation through shocks. This would have significant implications for all binary systems: e.g. accretion outbursts in X-ray binaries and fuelling supermassive black hole (SMBH) binaries. The behaviour we have discussed in this work is relevant to a variety of astrophysical systems, for example X-ray binaries, where the disc plane may be tilted by radiation warping, SMBH binaries, where accretion of misaligned gas can create effectively random inclinations and protostellar binaries, where a disc may be misaligned by a variety of effects such as binary capture/exchange, accretion after binary formation.

  14. Small Break Air Ingress Experiment

    Energy Technology Data Exchange (ETDEWEB)

    Chang Oh; Eung Soo Kim

    2011-09-01

    The small break air-ingress experiment, described in this report, is designed to investigate air-ingress phenomena postulated to occur in pipes in a very high temperature gas-cooled reactor (VHTRs). During this experiment, air-ingress rates were measured for various flow and break conditions through small holes drilled into a pipe of the experimental apparatus. The holes were drilled at right angles to the pipe wall such that a direction vector drawn from the pipe centerline to the center of each hole was at right angles with respect to the pipe centerline. Thus the orientation of each hole was obtained by measuring the included angle between the direction vector of each hole with respect to a reference line anchored on the pipe centerline and pointing in the direction of the gravitational force. Using this reference system, the influence of several important parameters on the air ingress flow rate were measured including break orientation, break size, and flow velocity . The approach used to study the influence of these parameters on air ingress is based on measuring the changes in oxygen concentrations at various locations in the helium flow circulation system as a function of time using oxygen sensors (or detectors) to estimate the air-ingress rates through the holes. The test-section is constructed of a stainless steel pipe which had small holes drilled at the desired locations.

  15. Inflationary implications of supersymmetry breaking

    NARCIS (Netherlands)

    Borghese, Andrea; Roest, Diederik; Zavala, Ivonne

    2013-01-01

    We discuss a general bound on the possibility to realise inflation in any minimal supergravity with F-terms. The derivation crucially depends on the sGoldstini, the scalar field directions that are singled out by spontaneous supersymmetry breaking. The resulting bound involves both slow-roll paramet

  16. Punishing adolescents

    DEFF Research Database (Denmark)

    Ryberg, Jesper

    2014-01-01

    Should an adolescent offender be punished more leniently than an adult offender? Many theorists believe the answer to be in the affirmative. According to the diminished culpability model, adolescents are less mature than adults and, therefore, less responsible for their wrongdoings and should...

  17. Adolescent Literacy

    Science.gov (United States)

    Ippolito, Jacy, Ed.; Steele, Jennifer L., Ed.; Samson, Jennifer F., Ed.

    2012-01-01

    "Adolescent Literacy" initially appeared as a special issue of the "Harvard Educational Review". It explores key issues and debates in the adolescent literacy crisis, the popular use of cognitive strategies, and disciplinary and content-area literacy. Also examined are alternative forms of literacy, afterschool interventions, new instruction…

  18. Treating Meningitis

    Science.gov (United States)

    ... David C. Spencer, MD Steven Karceski, MD Treating meningitis Steven Karceski, MD WHAT DID THE AUTHORS STUDY? ... study, “ Dexamethasone and long-term survival in bacterial meningitis, ” Dr. Fritz and his colleagues carefully evaluated 2 ...

  19. Gender dysphoria in adolescence.

    Science.gov (United States)

    Leibowitz, Scott; de Vries, Annelou L C

    2016-01-01

    Adolescents presenting with gender-related concerns are increasingly seeking support from providers from a variety of disciplines within health care settings across the world. For those treating young people who meet the criteria for the DSM 5 diagnosis of gender dysphoria (GD), complex decisions in clinical care are common. Defining best practice with this population with respect to interventions that span mental health, physical, and surgical domains can be challenging, given a relative dearth of empirical data available; yet practice guidelines have emerged from different professional organizations which can aid with this. For this review paper, a broad literature search was performed to identify relevant studies pertaining to the care of adolescents with GD. In addition, an overview of trends in clinical practice, including shifts in conceptualization of how clinicians and patients define care that is considered affirming when working with this population, is described. This paper explores the characteristics of referral patterns to specialized clinics, provides a brief overview of gender identity development in adolescence, and then describes the phenomenology of known aetiological factors and co-occurring psychiatric issues in adolescents with GD. Additionally, clinical management considerations that detail assessment aims and common treatment interventions across disciplines will be explored. PMID:26828376

  20. A model of intrinsic symmetry breaking

    Energy Technology Data Exchange (ETDEWEB)

    Ge, Li [Research Center for Quantum Manipulation, Department of Physics, Fudan University, Shanghai 200433 (China); Li, Sheng [Department of Physics, Zhejiang Normal University, Zhejiang 310004 (China); George, Thomas F., E-mail: tfgeorge@umsl.edu [Office of the Chancellor and Center for Nanoscience, Department of Chemistry and Biochemistry, University of Missouri-St. Louis, St. Louis, MO 63121 (United States); Department of Physics and Astronomy, University of Missouri-St. Louis, St. Louis, MO 63121 (United States); Sun, Xin, E-mail: xin_sun@fudan.edu.cn [Research Center for Quantum Manipulation, Department of Physics, Fudan University, Shanghai 200433 (China)

    2013-11-01

    Different from the symmetry breaking associated with a phase transition, which occurs when the controlling parameter is manipulated across a critical point, the symmetry breaking presented in this Letter does not need parameter manipulation. Instead, the system itself suddenly undergoes symmetry breaking at a certain time during its evolution, which is intrinsic symmetry breaking. Through a polymer model, it is revealed that the origin of the intrinsic symmetry breaking is nonlinearity, which produces instability at the instance when the evolution crosses an inflexion point, where this instability breaks the original symmetry.

  1. Presowing treatments for breaking seed dormancy of Hovenia dulcis Thunb.

    OpenAIRE

    Grbić Mihailo; Skočajić Dragana; Đukić Matilda; Đunisijević Danijela

    2006-01-01

    The aim of the experiment was to determine the optimal presowing treat­ment for breaking seed dormancy of Japanese raisin tree (Hovenia dulcis Thunb.), a very rare exotic species introduced to the Mediterranean parts of Serbia and Mon­tenegro. Three pretreatments are applied: mechanical scarification and chemical scarification (conc. H2SO4) lasting for 5 and 120 minutes. The best treatment was the longer chemical scarification, which confirmed the dormancy of the seedcoat.

  2. Presowing treatments for breaking seed dormancy of Hovenia dulcis Thunb.

    Directory of Open Access Journals (Sweden)

    Grbić Mihailo

    2006-01-01

    Full Text Available The aim of the experiment was to determine the optimal presowing treat­ment for breaking seed dormancy of Japanese raisin tree (Hovenia dulcis Thunb., a very rare exotic species introduced to the Mediterranean parts of Serbia and Mon­tenegro. Three pretreatments are applied: mechanical scarification and chemical scarification (conc. H2SO4 lasting for 5 and 120 minutes. The best treatment was the longer chemical scarification, which confirmed the dormancy of the seedcoat.

  3. Stages of Adolescence

    Science.gov (United States)

    ... Español Text Size Email Print Share Stages of Adolescence Page Content Article Body Adolescence, these years from puberty to adulthood, may be roughly divided into three stages: early adolescence, generally ages eleven to fourteen; middle adolescence, ages ...

  4. Breaking GSM with rainbow Tables

    CERN Document Server

    Meyer, Steven

    2011-01-01

    Since 1998 the GSM security has been academically broken but no real attack has ever been done until in 2008 when two engineers of Pico Computing (FPGA manufacture) revealed that they could break the GSM encryption in 30 seconds with 200'000$ hardware and precomputed rainbow tables. Since then the hardware was either available for rich people only or was confiscated by government agencies. So Chris Paget and Karsten Nohl decided to react and do the same thing but in a distributed open source form (on torrent). This way everybody could "enjoy" breaking GSM security and operators will be forced to upgrade the GSM protocol that is being used by more than 4 billion users and that is more than 20 years old.

  5. Renormalizable theories with symmetry breaking

    CERN Document Server

    Becchi, Carlo M

    2016-01-01

    The description of symmetry breaking proposed by K. Symanzik within the framework of renormalizable theories is generalized from the geometrical point of view. For an arbitrary compact Lie group, a soft breaking of arbitrary covariance, and an arbitrary field multiplet, the expected integrated Ward identities are shown to hold to all orders of renormalized perturbation theory provided the Lagrangian is suitably chosen. The corresponding local Ward identity which provides the Lagrangian version of current algebra through the coupling to an external, classical, Yang-Mills field, is then proved to hold up to the classical Adler-Bardeen anomaly whose general form is written down. The BPHZ renormalization scheme is used throughout in such a way that the algebraic structure analyzed in the present context may serve as an introduction to the study of fully quantized gauge theories.

  6. Symmetry breaking in supersymmetric GUTs

    International Nuclear Information System (INIS)

    This paper analyzes the first step of symmetry breaking in N=1 supersymmetric unified theories. The possible patterns of gauge symmetry breaking consistent with supersymmetry are characterized. Some well-known properties of the scalar potential in supersymmetric gauge theories are reviewed. Simple methods to discover which v.e.v.'s of a given multiplet of scalar fields are consistent with the conditions of given equations are introduced. The vanishing of the D2-term and of the F2-term is discussed and a simple lemma derived from the former. The results of these discussions are applied to some possible candidates for a supersymmetric gauge theory based on the gauge groups SU(5), 0(10), and E6

  7. Symmetries, Symmetry Breaking, Gauge Symmetries

    CERN Document Server

    Strocchi, Franco

    2015-01-01

    The concepts of symmetry, symmetry breaking and gauge symmetries are discussed, their operational meaning being displayed by the observables {\\em and} the (physical) states. For infinitely extended systems the states fall into physically disjoint {\\em phases} characterized by their behavior at infinity or boundary conditions, encoded in the ground state, which provide the cause of symmetry breaking without contradicting Curie Principle. Global gauge symmetries, not seen by the observables, are nevertheless displayed by detectable properties of the states (superselected quantum numbers and parastatistics). Local gauge symmetries are not seen also by the physical states; they appear only in non-positive representations of field algebras. Their role at the Lagrangian level is merely to ensure the validity on the physical states of local Gauss laws, obeyed by the currents which generate the corresponding global gauge symmetries; they are responsible for most distinctive physical properties of gauge quantum field ...

  8. Breaking of de Sitter Symmetry

    CERN Document Server

    Bander, Myron

    2010-01-01

    We show that an interacting spin-0 field on a de Sitter space background will break the underlying de Sitter symmetry. This is done first for a (1+1) de Sitter space where a boson-fermion correspondence permits us to solve certain interacting theories by transforming them into free ones of opposite statistics. A massless boson interacting by a sine-Gordon potential is shown to be equivalent to a free massive fermion with the mass depending on the de Sitter time thus breaking the symmetry explicitly. We then show that for larger dimensions and any boson potential, to one loop, an anomaly develops and the currents generating the de Sitter transformations are not conserved.

  9. Complete quantum measurements break entanglement

    International Nuclear Information System (INIS)

    A complete measurement of a quantum observable (POVM) is a measurement of the maximally refined version of the POVM. Complete measurements give information on multiplicities of measurement outcomes and can be used as state preparation procedures. Moreover, any observable can be measured completely. In this Letter, we show that a complete measurement breaks entanglement completely between the system, ancilla and their environment. Finally, consequences for the quantum Zeno effect and complete position measurements are discussed.

  10. Linhas escleróticas metafisárias em crianças e adolescentes em uso de alendronato Sclerotic metaphyseal lines in children and adolescents treated with alendronate

    Directory of Open Access Journals (Sweden)

    Érika C.C. Silva

    2010-06-01

    Full Text Available INTRODUÇÃO: Os bisfosfonatos inibem a reabsorção óssea pela interferência na ação dos osteoclastos. Dentre os efeitos adversos, as linhas escleróticas em metáfise de ossos longos são descritas como principal alteração radiográfica na faixa etária pediátrica. OBJETIVO: Avaliar a frequência de alterações radiográficas causadas pelo alendronato utilizado em crianças e adolescentes com baixa densidade óssea ou calcinose. PACIENTES E MÉTODOS: Foi realizado um estudo do tipo coorte retrospectiva analisando-se prontuários de 21 pacientes que fizeram uso de alendronato semanal por no mínimo 10 meses. Os pacientes realizaram radiografias de ossos longos antes do início do alendronato e aproximadamente um ano após o seu uso. RESULTADOS: Onze pacientes (52,3% apresentaram linhas escleróticas em metáfise dos ossos longos. A localização mais frequente foi em tíbia (8/11 pacientes, seguida de fêmur (7/11, úmero (6/11, rádio (4/11, ulna (3/11 e fíbula (2/11. Nenhum paciente apresentou regress��o das alterações radiográficas durante o tempo de evolução (até 1,1 ano após a suspensão do alendronato. CONCLUSÃO: Se usado com critério, o alendronato é seguro e as alterações radiográficas não mostraram ter um significado mais importante.INTRODUCTION: Bisphosphonates inhibit bone resorption by interfering with the action of osteoclasts. Among the adverse effects, sclerotic lines observed in the metaphysis of long bones have been described as the main imaging finding in pediatric patients. OBJECTIVE: To evaluate the frequency of radiographic changes caused by alendronate in children and adolescents with low bone density or calcinosis. PATIENTS AND METHODS: We conducted a cross-sectional study with 21 patients who were treated with once-weekly alendronate for at least 10 months. Patients underwent x-rays of long bones before the start of alendronate and approximately one year after its use. RESULTS: Eleven patients

  11. 16th Edition Breaks New Ground

    Institute of Scientific and Technical Information of China (English)

    Zhao Fei

    2010-01-01

    @@ Breaking new ground,Intertextile Shanghai Apparel Fabrics,successfully closed its doors on October 22nd,2010at the Shanghai New International Exhibition Centre,attracting a record breaking,more than 57,000 buyers.

  12. Spontaneous Breaking of the Quantum Superposition

    OpenAIRE

    Pankovic, Vladan; Predojevic, Milan

    2007-01-01

    In this work spontaneous (non-dynamical) breaking (effective hiding) of the unitary quantum mechanical dynamical symmetry (superposition) is considered. It represents an especial but very interesting case of the general formalism of the spontaneous symmetry breaking (effective hiding). Conceptual analogies with spontaneous breaking of the gauge symmetry in Weinberg-Sallam's electro-weak interaction are pointed out. Also, consequences of the spontaneous superposition breaking in the measuremen...

  13. Tricky Treats

    Centers for Disease Control (CDC) Podcasts

    2008-08-04

    The Eagle Books are a series of four books that are brought to life by wise animal characters - Mr. Eagle, Miss Rabbit, and Coyote - who engage Rain That Dances and his young friends in the joy of physical activity, eating healthy foods, and learning from their elders about health and diabetes prevention. Tricky Treats shows children the difference between healthy snacks and sweet treats.  Created: 8/4/2008 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP).   Date Released: 8/5/2008.

  14. Electroweak symmetry breaking at photon colliders

    International Nuclear Information System (INIS)

    The electroweak-symmetry-breaking sector of the standard model can be weakly-coupled or can be strongly-coupled, which is characterized by some kinds of strong interaction among the Goldstone bosons of the electroweak-symmetry-breaking sector. In this paper, we summarize an investigation of probing the strong electroweak-symmetry-breaking effects at photon colliders. ((orig.))

  15. Exploring Cartan gravity with dynamical symmetry breaking

    International Nuclear Information System (INIS)

    It has been known for some time that General Relativity can be regarded as a Yang–Mills-type gauge theory in a symmetry broken phase. In this picture the gravity sector is described by an SO(1, 4) or SO(2, 3) gauge field Abμa and Higgs field Va which acts to break the symmetry down to that of the Lorentz group SO(1, 3). This symmetry breaking mirrors that of electroweak theory. However, a notable difference is that while the Higgs field Φ of electroweak theory is taken as a genuine dynamical field satisfying a Klein–Gordon equation, the gauge independent norm V2 ≡ ηabVaVb of the Higgs-type field Va is typically regarded as non-dynamical. Instead, in many treatments Va does not appear explicitly in the formalism or is required to satisfy V2 = const. ≠ 0 by means of a Lagrangian constraint. As an alternative to this we propose a class of polynomial actions that treat both the gauge connection Abμa and Higgs field Va as genuine dynamical fields with no ad hoc constraints imposed. The resultant equations of motion consist of a set of first-order partial differential equations. We show that for certain actions these equations may be cast in a second-order form, corresponding to a scalar–tensor model of gravity. One simple choice leads to the extensively studied Peebles–Ratra rolling quintessence model. Another choice yields a scalar–tensor symmetry broken phase of the theory with positive cosmological constant and an effective mass M of the gravitational Higgs field ensuring the constancy of V2 at low energies and agreement with empirical data if M is sufficiently large. More general cases are discussed corresponding to variants of Chern–Simons modified gravity and scalar-Euler form gravity, each of which yield propagating torsion. (paper)

  16. Management of psoriasis in adolescence

    Directory of Open Access Journals (Sweden)

    Fotiadou C

    2014-03-01

    Full Text Available Christina Fotiadou, Elizabeth Lazaridou, Demetrios Ioannides First Department of Dermatology–Venereology, Aristotle University Medical School, Thessaloniki, Greece Abstract: Psoriasis is a chronic inflammatory cutaneous disorder affecting 2%–4% of the world's population. The prevalence of the disease in childhood and adolescence ranges between 0.5% and 2%. The management of psoriasis in adolescence is an intriguing and complicated task. Given the paucity of officially approved therapies, the very limited evidence-based data from randomized controlled trials, and the absence of standardized guidelines, physicians must rely on published experience from case reports both from the field of dermatology as well as from the application of these drugs for other pediatric conditions coming from the disciplines of rheumatology, gastroenterology, and oncology. Psoriatic adolescents deal with a potentially disfiguring and lifelong disease that could permanently impair their psychological development. It must be clarified to them that psoriasis does not have a permanent cure, and therefore the main goal of treatments is to establish disease control and prolonged periods between flares. The majority of adolescents suffer from mild psoriasis, and thus they are treated basically with topical treatment modalities. Phototherapy is reserved for adolescents with mild-to-moderate plaque disease and/or guttate psoriasis when routine visits to specialized centers do not create practical problems. Systemic agents and biologics are administered to patients with moderate-to-severe plaque psoriasis, pustular psoriasis, or erythrodermic psoriasis. Keywords: adolescent psoriasis, pediatric psoriasis, treatment, systemic treatment, biologic agents

  17. Pharmacotherapy of inattention and ADHD in adolescents.

    Science.gov (United States)

    McBurnett, Keith; Swetye, Michael; Muhr, Heather; Hendren, Robert L

    2013-08-01

    This article reviews the current use of stimulants in adolescents. The evidence base for treatment of attention-deficit/hyperactivity disorder (ADHD) in adolescents is meager compared with that of ADHD in children, and much recent research of older populations with ADHD has been directed toward adults rather than adolescents. The structure of psychosocial treatment of ADHD differs across developmental ranges. For example, in children, treatment of ADHD uses direct behavior modification via parents and teachers. Treatment approaches then change toward contracting in adolescents (acknowledging the emerging independence common at this age) and toward self-management and coaching in adults. Medication for ADHD, however, does not substantially differ across developmental epochs. In supplementation of data, specifically on adolescence, much of our understanding of treating adolescents comes from upward or downward extension of the child and adult data. Symptomatic treatment (treatment for inattention, hyperactivity, or impulsive behavior) has always been a parallel approach to diagnostic and developmentally specific selection of treatment based on an incomplete literature. In recognition, this article assumes that inference from children or adults to adolescents, in the absence of adolescent-specific data, is commonplace and often confirmed with clinical experience. Such inferences, in the face of literature gaps, in no way obviate the need for continued research focused on adolescence. PMID:24298754

  18. Adolescent pregnancy.

    Science.gov (United States)

    Short, J D; Slusher, I L

    1994-01-01

    Kentucky has the fourth highest percentage of infants born to teenage mothers in the US. Risk factors for adolescent pregnancy are poor academic performance, family history of adolescent pregnancy, absence of one or both biological parents in the home, troubled family relationships, family violence, history of substance abuse, and poor self-concept. Pregnancy adds new developmental requirements to the continual developmental crisis of adolescence. Some of these developmental requirements are dealing with pregnancy and birth of a child and peer and family reactions and relationships. Pregnant teens are at high risk for anemia, preeclampsia, preterm delivery, and low birth weight infants. The health care team must assess the abilities, needs, practices, and priorities of teens. Nurses should promote health and positive health practices in teens. They should focus on prevention of adolescent pregnancy and on meeting the needs of pregnant teens. Adolescent pregnancy interventions include education and adolescent-centered special programs. Peer groups, role playing, videos, and computer games are individualized and effective education techniques for teens. Formal adolescent pregnancy prevention programs are abstinence education, knowledge-based programs, and clinic-focused or school-based programs. A combination of approaches is more effective than using just one approach. Adolescent pregnancy prevention interventions should promote the value of education, discourage substance abuse, and provide counseling for victims of child abuse. Pregnant teens should receive prenatal care as soon as possible. One health care agency should combine physical care, psychosocial support, and education for teens. Kentucky schools help pregnant teens continue their education and help them obtain information and support for care for themselves and their babies. Nurses can be effective at reducing the number of unwanted teen pregnancies. PMID:7934083

  19. Early maladaptive schemas and their relationship to psychopathology in adolescence

    OpenAIRE

    Makinson, Jenny Elizabeth

    2013-01-01

    Schema therapy was developed by Jeffery Young to treat adults with personality disorders, and has been evidenced to be effective in treating both Axis I and Axis II disorders. While Young stipulates that schemas are likely to be in place by adolescence, there is currently little agreement over the appropriateness of schema theory and therapy in understanding and treating psychopathology in adolescence. This thesis aims to explore the evidence–base and potential utility of apply...

  20. Social influences on morphine sensitization in adolescent females

    OpenAIRE

    Hofford, Rebecca S.; Roberts, Kris W; Wellman, Paul J.; Eitan, Shoshana

    2010-01-01

    We recently observed that social interactions influence morphine responsiveness in adolescent males. Given sex-related differences in both social interactions and responses to morphine, the present study examines social influences on morphine sensitization in adolescent female mice. Four experimental groups were examined: [1] morphine-treated mice (twice daily, 10–40 mg/kg, s.c.) housed physically and visually separated from saline-treated mice (‘morphine only’), [2] morphine-treated mice hou...

  1. Narcolepsy in adolescents.

    Science.gov (United States)

    Sullivan, Shannon S

    2010-12-01

    Narcolepsy is a disorder of children and adolescence, but until recently it was often not identified until adulthood, with a reported time from onset to diagnosis of about a decade. This disorder affects approximately 0.05% of the population and starts in childhood and adolescence about half of the time. With narcolepsy, the boundaries between wake, sleep, and dreams are blurred. The cardinal features of narcolepsy-cataplexy are daytime somnolence, cataplexy (sometimes occurring long after onset of sleepiness), sleep paralysis, and hypnagogic hallucinations. Weight gain, disturbed nocturnal sleep, and social/school functional changes are common; reactive substance use to maintain wakefulness during the day may also be seen. Males and females are equally affected. It is classically associated with HLA DQB1*0602, the most specific genetic marker for narcolepsy across all ethnic groups. CSF hypocretin has recently been found to be depleted in this disorder, and late-breaking data support that the disease is caused by autoimmune destruction of hypocretin-producing neurons in the hypothalamus. There is no known cure for narcolepsy. Therapies include behavioral/ scheduling modification, medications to combat daytime sleepiness and cataplexy, and treatment of concomitant disorders leading to daytime sleepiness. The differential diagnosis for this disorder should include other disorders of excessive daytime sleepiness with a proclivity toward onset in adolescence, such as delayed sleep phase syndrome, obstructive sleep apnea, and insufficient sleep time; substance use; and less commonly neurologic disorders such as Klein Levin syndrome, Prader-Willi syndrome, and others. Immunomodulator therapy and hypocretin replacement are proposed therapies that hold promise for the future. PMID:21302860

  2. Interventions for treating obesity in children

    NARCIS (Netherlands)

    Oude Luttikhuis, Hiltje; Baur, Louise; Jansen, Hanneke; Shrewsbury, Vanessa A.; O'Malley, Claire; Stolk, Ronald P.; Summerbell, Carolyn D.

    2009-01-01

    Background Child and adolescent obesity is increasingly prevalent, and can be associated with significant short- and long-term health consequences. Objectives To assess the efficacy of lifestyle, drug and surgical interventions for treating obesity in childhood. Search strategy We searched CENTRAL o

  3. Breaking stress of neutron star crust

    CERN Document Server

    Chugunov, A I

    2010-01-01

    The breaking stress (the maximum of the stress-strain curve) of neutron star crust is important for neutron star physics including pulsar glitches, emission of gravitational waves from static mountains, and flares from star quakes. We perform many molecular dynamic simulations of the breaking stress at different coupling parameters (inverse temperatures) and strain rates. We describe our results with the Zhurkov model of strength. We apply this model to estimate the breaking stress for timescales ~1 s - 1 year, which are most important for applications, but much longer than can be directly simulated. At these timescales the breaking stress depends strongly on the temperature. For coupling parameter <200, matter breaks at very small stress, if it is applied for a few years. This viscoelastic creep can limit the lifetime of mountains on neutron stars. We also suggest an alternative model of timescale-independent breaking stress, which can be used to estimate an upper limit on the breaking stress.

  4. History of electroweak symmetry breaking

    CERN Document Server

    Kibble, T W B

    2015-01-01

    In this talk, I recall the history of the development of the unified electroweak theory, incorporating the symmetry-breaking Higgs mechanism, as I saw it from my standpoint as a member of Abdus Salam's group at Imperial College. I start by describing the state of physics in the years after the Second World War, explain how the goal of a unified gauge theory of weak and electromagnetic interactions emerged, the obstacles encountered, in particular the Goldstone theorem, and how they were overcome, followed by a brief account of more recent history, culminating in the historic discovery of the Higgs boson in 2012.

  5. Leaders break ground for INFINITY

    Science.gov (United States)

    2008-01-01

    Community leaders from Mississippi and Louisiana break ground for the new INFINITY at NASA Stennis Space Center facility during a Nov. 20 ceremony. Groundbreaking participants included (l to r): Gottfried Construction representative John Smith, Mississippi Highway Commissioner Wayne Brown, INFINITY board member and Apollo 13 astronaut Fred Haise, Stennis Director Gene Goldman, Studio South representative David Hardy, Leo Seal Jr. family representative Virginia Wagner, Hancock Bank President George Schloegel, Mississippi Rep. J.P. Compretta, Mississippi Band of Choctaw Indians representative Charlie Benn and Louisiana Sen. A.G. Crowe.

  6. History of electroweak symmetry breaking

    Science.gov (United States)

    Kibble, T. W. B.

    2015-07-01

    In this talk, I recall the history of the development of the unified electroweak theory, incorporating the symmetry-breaking Higgs mechanism, as I saw it from my standpoint as a member of Abdus Salam's group at Imperial College. I start by describing the state of physics in the years after the Second World War, explain how the goal of a unified gauge theory of weak and electromagnetic interactions emerged, the obstacles encountered, in particular the Goldstone theorem, and how they were overcome, followed by a brief account of more recent history, culminating in the historic discovery of the Higgs boson in 2012.

  7. Supersymmetry breaking in string theory

    International Nuclear Information System (INIS)

    I briefly review the problems with previous investigations of supersymmetry breaking in string theory --- at tree-level, at one-loop, and non-perturbatively. A variant of the original non-perturbative scenario is proposed, in which gaugino condensation takes place in two different strongly-interacting hidden-sector gauge groups. In the new scenario it is possible to generate a large hierarchy of mass scale and to simultaneously stabilize the dilaton at a large expectation value (weak coupling). However, it is still uncertain whether supersymmetry is broken in such a vacuum. 26 refs

  8. Spontaneous Breaking of Flavor Symmetry

    CERN Document Server

    Törnqvist, N A

    1996-01-01

    It is shown that part of the quark masses of the standard model can be generated spontaneously within the strong interactions of QCD. After the breaking of U(Nf) x U(Nf) symmetry by the vacuum, also the resulting flavor symmetric, degenerate meson mass spectrum is shown to be unstable with respect to quantum loops, for rather general models. For a C-degenerate meson spectrum the stable mass spectrum obeys the Okubo-Zweig-Iizuka rule and the approximateequal spacing rule.

  9. Breaking Carbon Lock-in

    DEFF Research Database (Denmark)

    Driscoll, Patrick Arthur

    2014-01-01

    This central focus of this paper is to highlight the ways in which path dependencies and increasing returns (network effects) serve to reinforce carbon lock-in in large-scale road transportation infrastructure projects. Breaking carbon lock-in requires drastic changes in the way we plan future...... transportation infrastructure projects, and documentary evidence presented here from the metropolitan regions of Copenhagen, Denmark and Portland, USA suggest that there may be a discontinuity in the system of automobility (Urry, 2004) thereby increasing the likelihood that such drastic measures may in fact be...

  10. Progress in Electroweak Symmetry Breaking

    CERN Document Server

    Dawson, S

    2015-01-01

    In this talk, I discuss theoretical advances in understanding the properties of the Higgs boson and the implications for models of electroweak symmetry breaking. I begin by reviewing some of the recent progress in Standard Model calculations for Higgs boson production and decay rates, followed by a lightning tour of the use of effective field theories in the search for new physics in the Higgs sector. I end with a discussion of the complementarity of precision Higgs coupling measurements and direct searches for heavy particles for the discovery of Beyond the Standard Model physics in the electroweak sector.

  11. Type III Guyon Syndrome in 'B Boy' Break-Dancer: A Case Report

    Science.gov (United States)

    Hu, Soo-young; Choi, Jin-gyu

    2015-01-01

    Although the musculoskeletal injuries associated with break-dancing which is gaining more popularity among adolescent and young people has been reported, the report regarding a peripheral nerve injury associated with breakdance is scarce. We report a rare case of a young amateur break-dancer, 'b-boy' who suffered from a painful paresthesia in his left hand, later diagnosed as type III Guyon's canal syndrome. A 23-year-old, right handed college man presented with a tenderness over the left hypothenar eminence and painful paresthesia over the ring and little fingers of 3 months duration. He trained himself as an amateur 'b boy' break-dancer for the last 10 months. Conservative management under the diagnosis of wrist sprain before presentation did not improve his hand pain. An magnetic resonance imaging and electrodiagnostic study revealed that painful paresthesia was caused by type III Guyon's canal syndrome, and 4 weeks of corticosteroid treatment was given with resolution of pain and paresthesia.

  12. Influence of night-breaks on flowering and phytohormones content in Hyoscyamus niger L.

    OpenAIRE

    Jan Kopcewicz; Gabriela Centkowska

    2014-01-01

    Night-breaks caused both stimulated shoot growth and caused formation of flowers as well as a general increase in the content of phytohormones in leaves of the long-day plant Hyoscyamus niger L. At the time of flower formation in night-break treated plants, new gibberellin-like substances also appear. The results show that night-breaks cause similar changes in the phytohormones content as a long inductive photoperiod. It may be assumed that independently of the way of induction, the generativ...

  13. [Adolescence: viewpoints from adolescent psychiatry].

    Science.gov (United States)

    Bürgin, D; von Klitzing, K

    1994-05-01

    Adolescence is a phase of human development which is marked by a high vulnerability due to the ongoing psycho-physiological transformations. The regulation of the self-esteem is especially in danger in youngsters who went into adolescence with a marked burden of conflicts or who lived in families with disturbed intrafamilial dynamics. To be present as a partner and not to find the solutions for the adolescents' conflicts, to accept their questioning of what is established and to recognize their movements of reconciliation are the quite complex demands put on to the world of the adults. Adolescents urge us to a review of our own adolescence, to a balancing of hate and love, openness and rigidity, and to dialectic movements between disintegration and reintegration as well as between the generations. Any help, be it on the physical, the social or the psychic level, should be directed toward a restitution of the intrapsychic, intrafamilial or intergenerational balance; sociocultural factors have also always to be respected. The helpers--especially in a culture with rapid change--are often confronted with their own adolescence, which took place a generation before and mostly under totally different conditions. PMID:8016759

  14. Boundary breaking for interdisciplinary learning

    Directory of Open Access Journals (Sweden)

    Adi Kidron

    2015-10-01

    Full Text Available The purpose of this work is to contribute to the body of knowledge on processesby which students develop interdisciplinary understanding of contents, as well as to suggest technology-enhanced means for supporting them in these processes in the context of higher education. In doing so, we suggest a rethinking of three traditional practices that tend to characterise typical higher education instruction: (1 compartmentalisation of disciplines; (2 traditional pedagogy; and (3 traditional hierarchies based on levels of expertise. Our high-level conjecture was that meaningful dialogue with peers and experts supports both the deepening of ideas in one knowledge domain and the formation of connections between ideas from several domains, both of which are required for the development of interdisciplinary understanding. We developed the Boundary Breaking for Interdisciplinary Learning (BBIL model, which harnesses technology to break boundaries between disciplines, learners and organisational levels of hierarchy. Findings indicate that 36 undergraduate students who participated in an interdisciplinary online course that implemented the BBIL model have significantly improved their interdisciplinary understanding of the course contents. This study illustrates how innovative use of available, free and low-cost technology can produce a ‘positive disruption’ in higher education instruction.

  15. Introduction to Electroweak Symmetry Breaking

    Energy Technology Data Exchange (ETDEWEB)

    Dawson,S.

    2008-10-02

    The Standard Model (SM) is the backbone of elementary particle physics-not only does it provide a consistent framework for studying the interactions of quark and leptons, but it also gives predictions which have been extensively tested experimentally. In these notes, I review the electroweak sector of the Standard Model, discuss the calculation of electroweak radiative corrections to observables, and summarize the status of SM Higgs boson searches. Despite the impressive experimental successes, however, the electroweak theory is not completely satisfactory and the mechanism of electroweak symmetry breaking is untested. I will discuss the logic behind the oft-repeated statement: 'There must be new physics at the TeV scale'. These lectures reflect my strongly held belief that upcoming results from the LHC will fundamentally change our understanding of electroweak symmetry breaking. In these lectures, I review the status of the electroweak sector of the Standard Model, with an emphasis on the importance of radiative corrections and searches for the Standard Model Higgs boson. A discussion of the special role of the TeV energy scale in electroweak physics is included.

  16. Chiral symmetry breaking and monopoles

    CERN Document Server

    Di Giacomo, Adriano; Pucci, Fabrizio

    2015-01-01

    To understand the relation between the chiral symmetry breaking and monopoles, the chiral condensate which is the order parameter of the chiral symmetry breaking is calculated in the $\\overline{\\mbox{MS}}$ scheme at 2 [GeV]. First, we add one pair of monopoles, varying the monopole charges $m_{c}$ from zero to four, to SU(3) quenched configurations by a monopole creation operator. The low-lying eigenvalues of the Overlap Dirac operator are computed from the gauge links of the normal configurations and the configurations with additional monopoles. Next, we compare the distributions of the nearest-neighbor spacing of the low-lying eigenvalues with the prediction of the random matrix theory. The low-lying eigenvalues not depending on the scale parameter $\\Sigma$ are compared to the prediction of the random matrix theory. The results show the consistency with the random matrix theory. Thus, the additional monopoles do not affect the low-lying eigenvalues. Moreover, we discover that the additional monopoles increa...

  17. [Vulnerability in adolescent health: contemporary issues].

    Science.gov (United States)

    Silva, Marta Angélica Iossi; Mello, Flávia Carvalho Malta de; Mello, Débora Falleiros de; Ferriani, Maria das Graças Carvalho; Sampaio, Julliane Messias Cordeiro; Oliveira, Wanderlei Abadio de

    2014-02-01

    The objective of this exploratory study with a qualitative approach was to analyze how adolescents perceive reality in terms of vulnerability in respect to health. A total of 17 semi-structured interviews were staged with adolescents from two elementary-middle (k-8) schools in a city in the interior of São Paulo, Brazil. Content analysis was used to interpret the data, from which three thematic nuclei emerged. The results revealed that the adolescents understand the complex interaction between individual predisposition and health vulnerability, as well as the issues related to social structure, which contributes to strengthening the concept of vulnerability based on individual, social and programmatic logic. It was established that public policies, prevention and care provided during adolescence should not be guided by a single reference point, but instead by the plurality of the adolescent individuals concerning vulnerability in their dimensions, which should be acknowledged in order to break with the idea of the universality of the process of becoming an adolescent. PMID:24863838

  18. Morning and evening behavior in children and adolescents treated with atomoxetine once daily for Attention-Deficit/Hyperactivity Disorder (ADHD: Findings from two 24-week, open-label studies

    Directory of Open Access Journals (Sweden)

    Schacht Alexander

    2009-02-01

    Full Text Available Abstract Background The impact of once daily atomoxetine treatment on symptoms in children and adolescents with ADHD may vary over the day. In order to capture such variations, two studies were undertaken in children and adolescents with ADHD using two instruments that capture morning and evening behavior and ADHD-related difficulties over the day. This secondary measure analysis builds on two primary analyses that were conducted separately for children and adolescents and also published separately. Methods In two open-label studies, ADHD patients aged 6–17 years (n = 421, received atomoxetine in the morning (target-dose 0.5–1.2 mg/kg/day for up to 24 weeks. Morning and evening behavior was assessed using the investigator-rated Weekly Rating of Evening and Morning Behavior (WREMB-R scale. ADHD-related difficulties at various times of the day (morning, during school, during homework, evening were assessed using the Global Impression of Perceived Difficulties (GIPD scale, rated by patients, parents and physicians. Data from both studies were combined for this secondary measure analysis. Results Both WREMB-R subscores decreased significantly over time, the evening subscore from 13.7 (95% CI 13.2;14.2 at baseline to 8.0 (7.4;8.5 at week 2, the morning subscore from 4.3 (4.0;4.5 to 2.4 (2.2;2.6. Scores then remained stable until week 24. All GIPD items improved correspondingly. At all times of the day, patients rated ADHD-related difficulties as less severe than parents and physicians. Conclusion These findings from two open-label studies suggest that morning and evening behavior and ADHD-related difficulties in the mornings and evenings improve over time with once daily atomoxetine treatment.

  19. Pajamas or Tuxedo? Digitalk and Formality in Adolescent Writing

    Science.gov (United States)

    Turner, Kristen H.

    2012-01-01

    Today's adolescents write to communicate--via text messaging, instant messaging, and social networking posts. They are skilled at manipulating their out-of-school digital language to communicate with an intended audience and to capture individual voice. Because the writing is informal, teens have the ability to break rules, and they can do so…

  20. Primary care management of depression in children and adolescents.

    Science.gov (United States)

    Haefner, Judy

    2016-06-19

    Depression is the most common mental health disorder in children and adolescents, and primary care is often the first point of contact for children and adolescents with depression. Depression impacts all areas of life, impairing academics and interactions with family and friends. The purpose of this article is to help NPs identify and treat children and adolescents presenting with depression in the primary care setting. PMID:27214067

  1. Clozapine for treatment of aggression in non-psychotic adolescents.

    Science.gov (United States)

    Kumar, Tarun; Kathpal, Archana; Demer, James

    2016-08-01

    Use of Second Generation Antipsychotics (SGAs) in children and adolescents has grown more significantly in recent years. Clozapine has shown good results for the treatment of aggression in adult population but no case has been reported about the use of clozapine for treatment of aggression in non-psychotic adolescents. We present cases of 2 adolescents in which clozapine was used primarily to treat their aggressive behavior and suicidal ideation. PMID:27520908

  2. Interpersonal Theory and Music Techniques: A Case Study for a Family With a Depressed Adolescent

    Science.gov (United States)

    Hendricks, C. Bret; Bradley, Loretta J.

    2005-01-01

    Interpersonal psychotherapy (IPT-A) is a brief, time-limited therapy developed for use with adolescents diagnosed with major depression. IPT-A has been shown to be effective with adolescents in family counseling milieus. Music therapy techniques also have been successfully used to treat adolescent depression. This article provides mental health…

  3. Nervousness and Performance Characteristics as Predictors of Peer Behavior towards Socially Anxious Adolescents

    Science.gov (United States)

    Blote, Anke W.; Duvekot, Jorieke; Schalk, Rozemarijn D. F.; Tuinenburg, Eveline M.; Westenberg, P. Michiel

    2010-01-01

    Social anxiety in adolescents has frequently been linked to negative outcomes from social interactions. The present study investigated whether socially anxious adolescents are treated negatively by their classmates and which characteristics of socially anxious adolescents could explain negative social responses. Classroom observations of class…

  4. Treatment of 56 Cases of Women with Post-adolescent Acne by Auricular Point Sticking Method

    Institute of Scientific and Technical Information of China (English)

    DING Min; JIANG Ya-qiu; CUI Xue-jun

    2008-01-01

    @@ Acne is a common disorder in adolescence. However, more and more patients are over 25 years old. This type of acne is recurrent, so it is called post-adolescence acne. The author treated 56 cases of women with post-adolescence acne by auricular point sticking method, and obtained excellent results. It is reported as follows.

  5. Gedanken Worlds without Higgs: QCD-Induced Electroweak Symmetry Breaking

    Energy Technology Data Exchange (ETDEWEB)

    Quigg, Chris; /Fermilab /Karlsruhe U., TTP; Shrock, Robert; /YITP, Stony Brook

    2009-01-01

    To illuminate how electroweak symmetry breaking shapes the physical world, we investigate toy models in which no Higgs fields or other constructs are introduced to induce spontaneous symmetry breaking. Two models incorporate the standard SU(3){sub c} {circle_times} SU(2){sub L} {circle_times} U(1){sub Y} gauge symmetry and fermion content similar to that of the standard model. The first class--like the standard electroweak theory--contains no bare mass terms, so the spontaneous breaking of chiral symmetry within quantum chromodynamics is the only source of electroweak symmetry breaking. The second class adds bare fermion masses sufficiently small that QCD remains the dominant source of electroweak symmetry breaking and the model can serve as a well-behaved low-energy effective field theory to energies somewhat above the hadronic scale. A third class of models is based on the left-right-symmetric SU(3){sub c} {circle_times} SU(2){sub L} {circle_times} SU(2){sub R} {circle_times} U(1)B?L gauge group. In a fourth class of models, built on SU(4){sub PS} {circle_times} SU(2){sub L} {circle_times} SU(2){sub R} gauge symmetry, lepton number is treated as a fourth color. Many interesting characteristics of the models stem from the fact that the effective strength of the weak interactions is much closer to that of the residual strong interactions than in the real world. The Higgs-free models not only provide informative contrasts to the real world, but also lead us to consider intriguing issues in the application of field theory to the real world.

  6. Electroweak Symmetry Breaking by QCD

    CERN Document Server

    Kubo, Jisuke; Lindner, Manfred

    2014-01-01

    We propose a new mechanism to generate the electroweak scale within the framework of QCD, which is extended to include conformally invariant scalar degrees of freedom belonging to a larger irreducible representation of $SU(3)_c$. The electroweak symmetry breaking is triggered dynamically via the Higgs portal by the condensation of the colored scalar field around $1$ TeV. The mass of the colored boson is restricted to be $350$ GeV $\\lesssim m_S\\lesssim 3$ TeV, with the upper bound obtained from renormalization group evolution. This implies that the colored boson can be produced at LHC. If the colored boson is electrically charged, the branching fraction of the Higgs decaying into two photons can slightly increase, and moreover, it can be produced at future linear colliders.

  7. Symmetry Breaking in Finite Volume

    Institute of Scientific and Technical Information of China (English)

    LIU Chuan

    2000-01-01

    Spontaneous symmetry breaking is a cooperative phenomenon for systems with infinitely many degrees of freedom and it plays an essential role in quantum field theories. Lattice O(N) model is studied within the Hamiltonian approach using an adiabatic approximation. It is shown that the low-lying spectrum of the system in the broken phase can be understood by using the adiabatic, or Born-Oppenheimer approximation, which turns out to become an expansion in the inverse power of volume. In the infinite volume limit, the symmetry is broken while in the finite volume the slow rotation of the zero-momentum mode restores the symmetry and gives rise to the rotator spectrum, which has been observed in realistic Monte Carlo simulations.

  8. Z'-mediated supersymmetry breaking.

    Science.gov (United States)

    Langacker, Paul; Paz, Gil; Wang, Lian-Tao; Yavin, Itay

    2008-02-01

    We consider a class of models in which supersymmetry breaking is communicated dominantly via a U1' gauge interaction, which also helps solve the mu problem. Such models can emerge naturally in top-down constructions and are a version of split supersymmetry. The spectrum contains heavy sfermions, Higgsinos, exotics, and Z' approximately 10-100 TeV, light gauginos approximately 100-1000 GeV, a light Higgs boson approximately 140 GeV, and a light singlino. A specific set of U1' charges and exotics is analyzed, and we present five benchmark models. The implications for the gluino lifetime, cold dark matter, and the gravitino and neutrino masses are discussed. PMID:18352261

  9. Dynamical centrosymmetry breaking in graphene

    CERN Document Server

    Carvalho, David N; Biancalana, Fabio

    2016-01-01

    We discover an unusual phenomenon that occurs when a graphene monolayer is illuminated by a short and intense pulse at normal incidence. Due to the pulse-induced oscillations of the Dirac cones, a dynamical breaking of the layer's centrosymmetry takes place, leading to the generation of second harmonic waves. We prove that this result can only be found by using the full Dirac equation and show that the widely used semiconductor Bloch equations fail to reproduce this and some other important physics of graphene. Our results open new windows in the understanding of nonlinear light-matter interactions in a wide variety of new 2D materials with a gapped or ungapped Dirac-like dispersion.

  10. Breaking the cycle of abuse.

    Science.gov (United States)

    Egeland, B; Jacobvitz, D; Sroufe, L A

    1988-08-01

    The aim of this study was to identify variables that distinguish mothers who broke the cycle of abuse from mothers who were abused as children and who also abused their own children. Based on maternal interviews and questionnaires completed over a 64-month period, measures of mothers' past and current relationship experiences, stressful life events, and personality characteristics were obtained. Abused mothers who were able to break the abusive cycle were significantly more likely to have received emotional support from a nonabusive adult during childhood, participated in therapy during any period of their lives, and to have had a nonabusive and more stable, emotionally supportive, and satisfying relationship with a mate. Abused mothers who reenacted their maltreatment with their own children experienced significantly more life stress and were more anxious, dependent, immature, and depressed. PMID:3168615

  11. Mutual information and spontaneous symmetry breaking

    OpenAIRE

    Hamma, A.; Giampaolo, S. M.; Illuminati, F.

    2015-01-01

    We show that the metastable, symmetry-breaking ground states of quantum many-body Hamiltonians have vanishing quantum mutual information between macroscopically separated regions, and are thus the most classical ones among all possible quantum ground states. This statement is obvious only when the symmetry-breaking ground states are simple product states, e.g. at the factorization point. On the other hand, symmetry-breaking states are in general entangled along the entire ordered phase, and t...

  12. Gravity with background fields and diffeomorphism breaking

    CERN Document Server

    Bluhm, Robert

    2016-01-01

    Effective gravitational field theories with background fields break local Lorentz symmetry and diffeomorphism invariance. Examples include Chern-Simons gravity, massive gravity, and the Standard-Model Extension (SME). The physical properties and behavior of these theories depend greatly on whether the spacetime symmetry breaking is explicit or spontaneous. With explicit breaking, the background fields are fixed and nondynamical, and the resulting theories are fundamentally different from Einstein's General Relativity (GR). However, when the symmetry breaking is spontaneous, the background fields are dynamical in origin, and many of the usual features of Einstein's GR still apply.

  13. Psychiatric Comorbidities among Female Adolescents with Anorexia Nervosa

    Science.gov (United States)

    Salbach-Andrae, Harriet; Lenz, Klaus; Simmendinger, Nicole; Klinkowski, Nora; Lehmkuhl, Ulrike; Pfeiffer, Ernst

    2008-01-01

    This study investigated current comorbid Axis I diagnoses associated with Anorexia Nervosa (AN) in adolescents. The sample included 101 female adolescents treated at a psychiatric unit for primary DSM-IV diagnoses of AN. 73.3% of the AN patients were diagnosed as having a current comorbidity of at least one comorbid Axis I diagnosis, with no…

  14. Unmotivated Adolescents.

    Science.gov (United States)

    Smith, Jill; Diller, Howard

    This book examines the characteristics and educational needs of unmotivated adolescents. It suggests that many of these students suffer from low self-esteem and are learning disabled and/or have an attention deficit disorder with hyperactivity. It offers a definition of learning disabilities that emphasizes the presence of significant differences…

  15. Adolescent Suicide.

    Science.gov (United States)

    Ray, Lynda Y.; Johnson, Norbert

    1983-01-01

    Explores the causes and symptoms of adolescent suicide including depression, loss of parent, alienation from family, and a mystical concept of death. Treatment procedures with unsuccessful suicide attempters and their parents are described and prevention strategies are discussed which involve teachers and counselors as well as parents. (JAC)

  16. [Adolescent sexuality].

    Science.gov (United States)

    Calero, Juan del Rey

    2010-01-01

    The social Adolescent features are insecurity, narcissism, eroticism, more impetuosity than reason. 1/3 of adolescents have risk behaviour for health. The pregnancy rate in adolescent are 9/1,000 (11,720, the abort about 50 %). The total abort (2009) were 114,480. Increase the rate of 8,4 (1990) to 14,6/ 1,000 (2009). The sexual education fails. The consulting about contraceptives get pregnancy of the OR 3,2, condom OR 2,7. The adolescent are influenced in his matter: oeer have 70-75 % of influence, mother 30-40 %, father 15 %, for yhe environment and education Cyberspace access to information: 33 % exposed to unwanted sexual materials, 1 in 7 solicited sexual online. The argument have 4 central topic: Morality and Responsibility, Desire (responsibility vs gratification), Danger (fear related to pregnancy and STD/VIH), and Victimization. The prevention of STD: so called safe sex, delayed, and abstinence, Prevention HPV vaccine. The information is not enough, are necessary personal integral formation in values as self control, abstinence, mutual respect, responsibility, reasonable decisions. PMID:21877398

  17. How Adolescent Girls Understand and Manage Depression Within Their Peer Group: A Grounded Theory Investigation

    OpenAIRE

    Pinto-Foltz, Melissa D.; Hines-Martin, Vicki; Logsdon, M. Cynthia

    2010-01-01

    Depression is prevalent among adolescent girls, but few receive mental health treatment. Adolescent girls often forgo needed mental health treatment because they fear responses of peers about depression. Understanding the processes of how adolescent girls respond to peers with depression is an important first step to improve access to mental health treatment. This qualitative study describes the knowledge, perceptions, and behaviors of adolescent girls about depression and mental health treat...

  18. On breaks of the Indian monsoon

    Indian Academy of Sciences (India)

    Sulochana Gadgil; P V Joseph

    2003-12-01

    For over a century, the term break has been used for spells in which the rainfall over the Indian monsoon zone is interrupted. The phenomenon of `break monsoon' is of great interest because long intense breaks are often associated with poor monsoon seasons. Such breaks have distinct circulation characteristics (heat trough type circulation) and have a large impact on rainfed agriculture.Although interruption of the monsoon rainfall is considered to be the most important feature of the break monsoon, traditionally breaks have been identified on the basis of the surface pressure and wind patterns over the Indian region. We have defined breaks (and active spells) on the basis of rainfall over the monsoon zone. The rainfall criteria are chosen so as to ensure a large overlap with the traditional breaks documented by Ramamurthy (1969) and De et al (1998). We have identified these rainbreaks for 1901-89. We have also identified active spells on the basis of rainfall over the Indian monsoon zone. We have shown that the all-India summer monsoon rainfall is significantly negatively correlated with the number of rainbreak days (correlation coefficient −0.56) and significantly positively correlated with the number of active days (correlation coefficient 0.47).Thus the interannual variation of the all-India summer monsoon rainfall is shown to be related to the number of days of rainbreaks and active spells identified here. There have been several studies of breaks (and also active spells in several cases) identified on the basis of different criteria over regions differing in spatial scales (e.g., Webster et al 1998; Krishnan et al 2000; Goswami and Mohan 2000; and Annamalai and Slingo 2001). We find that there is considerable overlap between the rainbreaks we have identified and breaks based on the traditional definition. There is some overlap with the breaks identified by Krishnan et al (2000) but little overlap with breaks identified by Webster et al (1998). Further

  19. Detecting Structural Breaks using Hidden Markov Models

    DEFF Research Database (Denmark)

    Ntantamis, Christos

    Testing for structural breaks and identifying their location is essential for econometric modeling. In this paper, a Hidden Markov Model (HMM) approach is used in order to perform these tasks. Breaks are defined as the data points where the underlying Markov Chain switches from one state to another...

  20. Electroweak Symmetry Breaking and the Higgs Boson

    CERN Document Server

    Pich, Antonio

    2015-01-01

    The first LHC run has confirmed the Standard Model as the correct theory at the electroweak scale, and the existence of a Higgs-like particle associated with the spontaneous breaking of the electroweak gauge symmetry. These lectures overview the present knowledge on the Higgs boson and discuss alternative scenarios of electroweak symmetry breaking which are already being constrained by the experimental data.

  1. Multiscale Simulation of Breaking Wave Impacts

    DEFF Research Database (Denmark)

    Lindberg, Ole

    compare reasonably well. The incompressible and inviscid ALE-WLS model is coupled with the potential flow model of Engsig-Karup et al. [2009], to perform multiscale calculation of breaking wave impacts on a vertical breakwater. The potential flow model provides accurate calculation of the wave...... potential flow model to provide multiscale calculation of forces from breaking wave impacts on structures....

  2. DNA Replication Reaches the Breaking Point

    OpenAIRE

    Petrini, John H.J.

    2009-01-01

    DNA strand breaks that result in stalled or damaged replication forks can be detrimental to the DNA replication process. In this issue, Doksani et al. (2009) examine the impact of a single double-stranded DNA break on replication in the budding yeast, Saccharomyces cerevisiae.

  3. Four Top Production and Electroweak Symmetry Breaking

    OpenAIRE

    Cheung, Kingman

    1995-01-01

    With the recent discovery of a heavy top quark $(m_t \\approx 175 - 200$ GeV), the top quark opens an window to electroweak symmetry breaking. We propose the study of four-top, $t\\bar t t\\bar t$, production at hadronic supercolliders as a probe to electroweak symmetry breaking.

  4. Anatomy of String Breaking in QCD

    OpenAIRE

    Prkacin, Zdravko; Bali, Gunnar S.; Dussel, Thomas; Lippert, Thomas; Neff, Hartmut; Schilling, Klaus

    2005-01-01

    We investigate the string breaking mechanism in n_f=2 QCD. We discuss the lattice techniques used and present results on energy levels and mixing angle of the static BBbar|QbarQ two-state system. The string breaking is visualized, by means of an animation of the action density distribution as a function of the static colour source-antisource separation.

  5. Big break for charge symmetry

    CERN Document Server

    Miller, G A

    2003-01-01

    Two new experiments have detected charge-symmetry breaking, the mechanism responsible for protons and neutrons having different masses. Symmetry is a crucial concept in the theories that describe the subatomic world because it has an intimate connection with the laws of conservation. The theory of the strong interaction between quarks - quantum chromodynamics - is approximately invariant under what is called charge symmetry. In other words, if we swap an up quark for a down quark, then the strong interaction will look almost the same. This symmetry is related to the concept of sup i sospin sup , and is not the same as charge conjugation (in which a particle is replaced by its antiparticle). Charge symmetry is broken by the competition between two different effects. The first is the small difference in mass between up and down quarks, which is about 200 times less than the mass of the proton. The second is their different electric charges. The up quark has a charge of +2/3 in units of the proton charge, while ...

  6. Research progress on dam-break floods

    KAUST Repository

    Wu, Jiansong

    2011-08-01

    Because of the catastrophic effects downstream of dam-break failure, more and more researchers around the world have been working on the study of dam-break flows to accurately forecast the downstream inundation mapping. With the rapid development of computer hardware and computing techniques, numerical study on dam-break flows has been a popular research subject. In the paper, the numerical methodologies used to solve the governing partial differential equations of dam-break flows are classified and summarized, and their characteristics and applications are discussed respectively. Furthermore, the fully-developed mathematical models developed in recent decades are reviewed, and also introduced the authors\\' on-going work. Finally, some possible future developments on modeling the dam-break flows and some solutions are presented and discussed. © 2011 IEEE.

  7. Supersymmetry Breaking by Higher Dimension Operators

    CERN Document Server

    Farakos, Fotis; Kehagias, Alex; Porrati, Massimo

    2014-01-01

    We discuss a supersymmetry breaking mechanism for N = 1 theories triggered by higher dimensional op- erators. We consider such operators for real linear and chiral spinor superfields that break superymmetry and reduce to the Volkov-Akulov action. We also consider supersymmetry breaking induced by a higher dimensional operator of a nonminimal scalar (complex linear) multiplet. The latter differs from the stan- dard chiral multiplet in its auxiliary sector, which contains, in addition to the complex scalar auxiliary of a chiral superfield, a complex vector and two spinors auxiliaries. By adding an appropriate higher di- mension operator, the scalar auxiliary may acquire a nonzero vev triggering spontaneous supersymmetry breaking. We find that the spectrum of the theory in the supersymmetry breaking vacuum consists of a free chiral multiplet and a constraint chiral superfield describing the goldstino. Interestingly, the latter turns out to be one of the auxiliary fermions, which becomes dynamical in the supersym...

  8. Mixing-induced spontaneous supersymmetry breaking

    International Nuclear Information System (INIS)

    It is conjectured that flavor mixing furnishes a universal mechanism for the spontaneous breaking of supersymmetry. The conjecture is proved explicitly for the mixing of two chiral N=1 supermultiplets and arguments for its general validity are given. That is an instance of the O'Raifeartaigh Lagrangian for which there is no tree-level nor perturbative breaking. Nonetheless, the dynamical breaking occurs due to the vacuum condensate, a mixing-induced nonperturbative effect that lifts the zero point energy. -- Highlights: → In this paper we propose a novel mechanism for spontaneous supersymmetry (SUSY) breaking based on flavor mixing. → We prove the conjecture in detail for the free massive Wess-Zumino case and give robust arguments for the general validity. → We present here is a dynamical SUSY breaking that is induced by a nonperturbative quantum effect.

  9. A laboratory study of breaking waves

    Directory of Open Access Journals (Sweden)

    Jaros³aw Têgowski

    2004-09-01

    Full Text Available This paper deals with some aspects of the wave-breaking phenomenon. The objectives were to study wave-breaking criteria, and the probability of whitecap coverage under fully controlled wave conditions. An additional task was to in vestigate the characteristic spectral features of the noise produced by breaking waves and the acoustic energy generated during wave breaking events. A controlled experiment was carried out in the Ocean Basin Laboratory at MARINTEK, Trondheim (Norway. Waves were generated by a computer-controlled multi-flap wave maker, which reproduced a realistic pattern of the sea surface for the prescribed spectra. Using wave staff recordings and photographic techniques, correlations between the breaking parameters and the radiated acoustic emissions were established.

  10. Low concentration of arsenite exacerbates UVR-induced DNA strand breaks by inhibiting PARP-1 activity

    International Nuclear Information System (INIS)

    Epidemiological studies have associated arsenic exposure with many types of human cancers. Arsenic has also been shown to act as a co-carcinogen even at low concentrations. However, the precise mechanism of its co-carcinogenic action is unknown. Recent studies indicate that arsenic can interfere with DNA-repair processes. Poly(ADP-ribose) polymerase (PARP)-1 is a zinc-finger DNA-repair protein, which can promptly sense DNA strand breaks and initiate DNA-repair pathways. In the present study, we tested the hypothesis that low concentrations of arsenic could inhibit PAPR-1 activity and so exacerbate levels of ultraviolet radiation (UVR)-induced DNA strand breaks. HaCat cells were treated with arsenite and/or UVR, and then DNA strand breaks were assessed by comet assay. Low concentrations of arsenite (≤ 2 μM) alone did not induce significant DNA strand breaks, but greatly enhanced the DNA strand breaks induced by UVR. Further studies showed that 2 μM arsenite effectively inhibited PARP-1 activity. Zinc supplementation of arsenite-treated cells restored PARP-1 activity and significantly diminished the exacerbating effect of arsenite on UVR-induced DNA strand breaks. Importantly, neither arsenite treatment, nor zinc supplementation changed UVR-triggered reactive oxygen species (ROS) formation, suggesting that their effects upon UVR-induced DNA strand breaks are not through a direct free radical mechanism. Combination treatments of arsenite with PARP-1 inhibitor 3-aminobenzamide or PARP-1 siRNA demonstrate that PARP-1 is the target of arsenite. Together, these findings show that arsenite at low concentration exacerbates UVR-induced DNA strand breaks by inhibiting PARP-1 activity, which may represent an important mechanism underlying the co-carcinogenicity of arsenic

  11. The effects of black garlic (Allium sativum L.) ethanol extract on the estimated total number of Purkinje cells and motor coordination of male adolescent Wistar rats treated with monosodium glutamate.

    Science.gov (United States)

    Aminuddin, M; Partadiredja, G; Sari, D C R

    2015-03-01

    A number of studies have indicated that monosodium glutamate (MSG) might cause negative effects on the nervous system, including in the cerebellum. Garlic (Allium sativum) has long been known as a flavouring agent and a traditional remedy for various illnesses. The present study aimed at investigating the effects of garlic on the motor coordination and the number of Purkinje cells present in rats treated with MSG. A total of 25 male Wistar rats aged 4 to 5 weeks old were used in this study and were divided into five groups, namely a negative control (C-) group, which received 0.9 % NaCl solution, a positive control (C+) group, which received MSG, and three treated groups, which received 2 mg/g bw of MSG and 2.5 mg (T2.5), 5 mg (T5), or 10 mg (T10) of black garlic solution per oral administration (per 200 g bw), respectively. All treatments were carried out for 10 days. Upon the end of the treatment, the motor performance of all rats were tested using the rotarod apparatus. The rats were subsequently sacrificed, and the cerebella of the rats were processed for stereological analyses. It has been found that the number of Purkinje cells of the cerebella of all treated groups were significantly higher than that of the group treated with MSG only. No changes in motor coordination function were observed as a result of MSG treatment. PMID:24737450

  12. The Relation between Popularity and Aggressive, Destructive, and Norm-Breaking Behaviors: Moderating Effects of Athletic Abilities, Physical Attractiveness, and Prosociality

    Science.gov (United States)

    Dijkstra, Jan Kornelis; Lindenberg, Siegwart; Verhulst, Frank C.; Ormel, Johan; Veenstra, Rene

    2009-01-01

    The aim of this study was to examine the relations between popularity and different types of aggressive, destructive, and norm-breaking behaviors in a large cross-sectional sample of adolescents (N=3,312, M age=13.60). We were interested in the extent to which the relations of these behaviors with popularity were moderated by positive features…

  13. Social influences on morphine sensitization in adolescent females.

    Science.gov (United States)

    Hofford, Rebecca S; Roberts, Kris W; Wellman, Paul J; Eitan, Shoshana

    2010-08-01

    We recently observed that social interactions influence morphine responsiveness in adolescent males. Given sex-related differences in both social interactions and responses to morphine, the present study examines social influences on morphine sensitization in adolescent female mice. Four experimental groups were examined: (1) morphine-treated mice (twice daily, 10-40 mg/kg, s.c.) housed physically and visually separated from saline-treated mice ('morphine only'), (2) morphine-treated mice housed together with saline-treated mice ('morphine cage-mates (of saline)'), (3) saline-treated mice housed together with morphine-treated mice ('saline cage-mates (of morphine)'), and (4) saline-treated mice housed physically and visually separated from morphine-treated mice ('saline only'). Following the treatment period, mice were tested individually for their locomotor response to 20 mg/kg morphine (s.c.). There were no significant differences in morphine-induced hyper-locomotion between saline only and saline cage-mates (of morphine) female adolescent mice. Notably, morphine only mice exhibited significantly greater morphine sensitization as compared to morphine cage-mates (of saline). Thus, this study demonstrates social influences on morphine sensitization in adolescent females. Drug use during early adolescence is a key predictor of later drug abuse and dependence during adulthood. Thus, understanding the specific vulnerabilities to drug use in this age group may represent a first step in helping develop more effective treatment programs. PMID:20456874

  14. Breaking stress of neutron star crust

    International Nuclear Information System (INIS)

    Complete text of publication follows. The breaking stress (the maximum of the stress-strain curve) of neutron star crust is important for neutron star physics including pulsar glitches, emission of gravitational waves from static mountains, and flares from star quakes. We perform many molecular dynamic simulations of the breaking stress at different coupling parameters (inverse temperatures), strain rates and composition of matter. We describe our results with the Zhurkov model of strength. We apply this model to estimate the breaking stress for timescales ∼1 s - 1 year, which are most important for applications, but much longer than can be directly simulated. At these timescales the breaking stress depends strongly on the temperature. For coupling parameter Γ<200 matter breaks at very small stress, if it is applied for a few years. This viscoelastic creep can limit the lifetime of mountains on neutron stars. We also suggest an alternative model of timescale-independent breaking stress, which can be used to estimate an upper limit on the breaking stress. This work was partially supported by the Russian Foundation for Basic Research (grant 11-02-00253-a), by the State Program 'Leading Scientific Schools of Russian Federation' (grant NSh 3769.2010.2), by the President grant for young Russian scientists (MK-5857.2010.2), by United States DOE grant (DE-FG02-87ER40365) and by Shared University Research grants from IBM, Inc. to Indiana University.

  15. Family dysfunction in adolescents with suicidal behavior and in adolescents with conduct disorders

    Directory of Open Access Journals (Sweden)

    Ivanović-Kovačević Svetlana

    2005-01-01

    Full Text Available Introduction. The period of life known as adolescence generally refers to transition from childhood to adulthood. Adolescents' progress toward autonomy involves remaining connected with, as well as separated from parents. Young people and their parents usually have mixed feelings about adolescent autonomy and attachment. An estimated 50% of children born in the 80s have spent part of their developmental years in single-parent households. Divorce is almost always a stressful event in children's lives. Youthful suicide rate has increased dramatically and is the third leading cause of death among 15-19 year olds. Conduct disorder is one of the most frequently diagnosed conditions in adolescents. Suicidal adolescents and adolescents with conduct disorder are much more likely than their peers to have grown up in disrupted, disorganized homes with lack of attachment between parents and their children. Material and methods This prospective study was carried out during 2002, 2003, and 2004. The research included 60 adolescents treated at the Center for Child and Adolescent Psychiatry in Novi Sad, 30 with diagnosed conduct disorder and 30 with suicidal behavior. Results Along with other kinds of distress, suicidal adolescents have experienced an escalation of family problems a few months prior to attempted suicide. Discussion Divorce and life in single-parent households is almost always a stressful period in children's lives. Conduct disorder and suicidal behavior represent a desperate cry for help. Conclusion Most adolescents in both groups live in single-parent house­holds. These young people have frequently passed into adolescence with little reason to feel that they could rely on their parents for support, or on their home as a place of sanctuary. .

  16. Studying Adolescence

    OpenAIRE

    Richter, Linda M.

    2006-01-01

    Young people in their teens constitute the largest age group in the world, in a special stage recognized across the globe as the link in the life cycle between childhood and adulthood. Longitudinal studies in both developed and developing countries and better measurements of adolescent behavior are producing new insights. The physical and psychosocial changes that occur during puberty make manifest generational and early-childhood risks to development, in the form of individual differences in...

  17. Dirac Neutrino Masses from Generalized Supersymmetry Breaking

    International Nuclear Information System (INIS)

    We demonstrate that Dirac neutrino masses in the experimentally preferred range are generated within supersymmetric gauge extensions of the standard model with a generalized supersymmetry breaking sector. If the superpotential neutrino Yukawa terms are forbidden by the gauge symmetry [such as a U(1)'], sub-eV scale effective Dirac mass terms can arise at tree level from hard supersymmetry breaking Yukawa couplings, or at one loop due to nonanalytic soft supersymmetry breaking trilinear scalar couplings. The radiative neutrino magnetic and electric dipole moments vanish at one-loop order

  18. Spontaneous chiral parity breaking by hydromagnetic buoyancy

    CERN Document Server

    Chatterjee, Piyali; Brandenburg, Axel; Rheinhardt, Matthias

    2010-01-01

    Evidence for a parity-breaking nature of the magnetic buoyancy instability in a stably stratified gas is reported. In the absence of rotation, no helicity is produced, but the non-helical state is found to be unstable to small helical perturbations during the development of the instability. The parity-breaking nature of an instability in magnetohydrodynamics appears to be the first of its kind and is similar to chiral symmetry breaking in biochemistry. Applications to the production of mean fields in galaxy clusters are being discussed.

  19. Spontaneous chiral symmetry breaking by hydromagnetic buoyancy

    Science.gov (United States)

    Chatterjee, Piyali; Mitra, Dhrubaditya; Brandenburg, Axel; Rheinhardt, Matthias

    2011-08-01

    Evidence for the parity-breaking nature of the magnetic buoyancy instability in a stably stratified gas is reported. In the absence of rotation, no helicity is produced, but the nonhelical state is found to be unstable to small helical perturbations during the development of the instability. The parity-breaking nature of this magnetohydrodynamic instability appears to be the first of its kind and has properties similar to those in chiral symmetry breaking in biochemistry. Applications to the production of mean fields in galaxy clusters are discussed.

  20. Infantile acne treated with oral isotretinoin

    DEFF Research Database (Denmark)

    Miller, Iben Marie; Echeverría, Begoña; Torrelo, Antonio;

    2013-01-01

    In contrast to adolescent acne, infantile acne (IA) is a rare condition with only a limited body of available literature. In this descriptive, retrospective study, we reviewed six cases from 2002 to 2010 treated with oral isotretinoin. The average age of onset was 6.16 months (range 0-21 mos......). Consistent with the previous, limited literature, we found predominantly boys are affected, a predilection for the cheeks, and a polymorphic inflammatory morphology. Two patients had a family history of acne. All cases were successfully and safely treated with oral isotretinoin. The suggested treatment of...... childhood acne is similar to that of adolescents (graded according to the severity of the skin disease and risk of scarring). Oral isotretinoin appears to be an effective and safe treatment for severe IA....

  1. Adolescent Interpersonal Communication Patterns

    OpenAIRE

    Grobler, S

    1999-01-01

    Adolescents are admitted to psychiatric wards presenting with psychiatric problems which are essentially secondary to problematic interpersonal relationships. Successful interpersonal relationships however depend on effective interpersonal communication. Therefore the aim of research on adolescent interpersonal communication was to explore and describe the interpersonal communication patterns of adolescents and to develop an interpersonal communication skills approach to facilitate adolescent...

  2. Adolescent Development: Workshop II.

    Science.gov (United States)

    Keng, Chiam Heng; And Others

    Workshops concerning adolescent development explored problems of adolescents, schooling and adolescence, preparation for adulthood, leisure and recreation, as well as values, culture, and change in relation to the development of youth. The discussion of adolescents' problems identified major problem areas, (emphasizing problems of communicating…

  3. Adolescent Attitudes about Rape.

    Science.gov (United States)

    Kershner, Ruth

    1996-01-01

    A very significant problem in society is adolescent rape victimization and the growing number of adolescent perpetrators. This paper examines adolescent attitudes about rape in order to develop curricular materials. It is found that adolescents exhibit conservative attitudes about gender roles, general rape myths, and victim issues. (Author)

  4. Breaking seed dormancy of three orthodox Mediterranean Rosaceae species.

    Science.gov (United States)

    Iakovoglou, Valasia; Radoglou, Kalliopi

    2015-03-01

    Biodiversity levels could be enhanced when regenerating a site by seed-derived seedlings. However, seed dormancy poses limitations for many species. As a result, nurseries either produce seedlings from species where dormancy is not an obstacle, or they propagate through cuttings with the risk of decreasing the genetic diversity within and among species at the regenerated sites. In the present study, breaking of seed dormancy was investigated in valuable Mediterranean species of Prunus avium, Prunus spinosa and Rosa canina Specifically, in order to break dormancy, seeds of those species were warm-, cold-stratified and chemically treated. Based on the results, maximum germination for P. avium was 12% when seeds were warm stratified for four weeks altered with eight weeks of cold stratification. For P. spinosa, maximum percent germination was 26% when seeds were warm stratified for two weeks and continuously altered for eight weeks of cold stratification. Finally, for R. canina maximum percent germination was 40% under four weeks of warm stratification altered with twenty weeks of cold stratification, when seeds were pretreated with H2SO4 for 15 min. A maximum of twelve weeks of cold stratification for P. avium, P. spinosa and 20 weeks for R. canina provided almost zero percent germination. The results indicated that all three species experienced intense dormancy levels suggesting that those species need to be treated properly prior to sowing. Nonetheless, additional experiments are needed to achieve greater germination percentage of highly valuable species in orderto encourage seed derived seedling production. PMID:25895254

  5. Formation of radiation-induced DNA breaks: the ratio of double-strand breaks to single-strand breaks

    International Nuclear Information System (INIS)

    Ionizing radiation causes the formation of strand breaks in cellular DNA, as well as other types of lesions in the chromatin of cells. Some of the earliest investigations of the molecular basis of radiation-induced damage and the implications of enzymatic repair were done by Dr. H. S. Kaplan. Because it is difficult to assay for DNA lesions in the large mammalian genome, the authors have developed a method of assaying for DNA double-strand breaks in the supercoiled nucleosome-complexed Simian virus 40 (SV40) genome, irradiated intracellularly. In this communication they present their measurements of the DNA double-strand breaks (DSBs) to single-strand breaks (SSBs) ratio obtained from the intracellularly irradiated SV40 genome. After cobalt gamma ray and X ray irradiations, this ratio is about 1/10. Their methods and results are compared with pertinent data in the literature. If the DSBs/SSBs ratio of 1/10 for cellular chromatin is correct, a substantial number of DNA double-strand breaks are formed in a mammalian cell after moderate doses (1 Gy) of radiation. The implications of different types of DNA double-strand breaks are discussed

  6. Unconventional supersymmetry and its breaking

    Energy Technology Data Exchange (ETDEWEB)

    Alvarez, Pedro D., E-mail: alvarez@physics.ox.ac.uk [Centro de Estudios Científicos (CECS), Av. Arturo Prat 514, Valdivia (Chile); Universidad Andrés Bello, Av. República 440, Santiago (Chile); Rudolf Peierls Centre for Theoretical Physics, University of Oxford, Oxford (United Kingdom); Pais, Pablo, E-mail: pais@cecs.cl [Centro de Estudios Científicos (CECS), Av. Arturo Prat 514, Valdivia (Chile); Universidad Andrés Bello, Av. República 440, Santiago (Chile); Zanelli, Jorge, E-mail: z@cecs.cl [Centro de Estudios Científicos (CECS), Av. Arturo Prat 514, Valdivia (Chile); Universidad Andrés Bello, Av. República 440, Santiago (Chile)

    2014-07-30

    We present a gauge theory for a superalgebra that includes an internal gauge (G) and local Lorentz (so(1,D−1)) algebras. These two symmetries are connected by fermionic supercharges. The field content of the system includes a (non-)abelian gauge potential A, a spin-1/2 Dirac spinor ψ, the Lorentz connection ω{sup ab}, and the vielbein e{sub μ}{sup a}. The connection one-form A is in the adjoint representation of G, while ψ is in the fundamental. In contrast to standard supersymmetry and supergravity, the metric is not a fundamental field and is in the center of the superalgebra: it is not only invariant under the internal gauge group, G, and under Lorentz transformations, SO(1,D−1), but is also invariant under supersymmetry. The distinctive features of this theory that mark the difference with standard supersymmetries are: i) the number of fermionic and bosonic states is not necessarily the same; ii) there are no superpartners with equal mass; iii) although this supersymmetry originates in a local gauge theory and gravity is included, there is no gravitino; iv) fermions acquire mass from their coupling to the background or from higher order self-couplings, while bosons remain massless. In odd dimensions, the Chern–Simons (CS) form provides an action that is (quasi-)invariant under the entire superalgebra. In even dimensions, the Yang–Mills (YM) form is the only natural option and the symmetry breaks down to G⊗SO(1,D−1). In four dimensions, the construction follows the Townsend–Mac Dowell–Mansouri approach, starting with an osp(4|2)∼usp(2,2|1) connection. Due to the absence of osp(4|2)-invariant traces in four dimensions, the resulting Lagrangian is only invariant under u(1)⊕so(3,1), which includes a Nambu–Jona-Lasinio (NJL) term. In this case, the Lagrangian depends on a single dimensionful parameter that fixes Newton's constant, the cosmological constant and the NJL coupling.

  7. Interventions for treating obesity in children

    OpenAIRE

    Oude Luttikhuis, Hiltje; Baur, Louise; Jansen, Hanneke; Shrewsbury, Vanessa A; O'Malley, Claire; Stolk, Ronald P.; Summerbell, Carolyn D

    2009-01-01

    Background Child and adolescent obesity is increasingly prevalent, and can be associated with significant short- and long-term health consequences. Objectives To assess the efficacy of lifestyle, drug and surgical interventions for treating obesity in childhood. Search strategy We searched CENTRAL on The Cochrane Library Issue 2 2008, MEDLINE, EMBASE, CINAHL, PsycINFO, ISI Web of Science, DARE and NHS EED. Searches were undertaken from 1985 to May 2008. References were checked. No language re...

  8. Dirac neutrino masses from generalized supersymmetry breaking

    International Nuclear Information System (INIS)

    We demonstrate that Dirac neutrino masses in the experimentally preferred range are generated within supersymmetric gauge extensions of the Standard Model with a generalized supersymmetry breaking sector. If the usual superpotential Yukawa couplings are forbidden by the additional gauge symmetry (such as a U(1)'), effective Dirac mass terms involving the ''wrong Higgs'' field can arise either at tree level due to hard supersymmetry breaking fermion Yukawa couplings, or at one-loop due to nonanalytic or ''nonholomorphic'' soft supersymmetry breaking trilinear scalar couplings. As both of these operators are naturally suppressed in generic models of supersymmetry breaking, the resulting neutrino masses are naturally in the sub-eV range. The neutrino magnetic and electric dipole moments resulting from the radiative mechanism also vanish at one-loop order. (orig.)

  9. Dirac Neutrino Masses from Generalized Supersymmetry Breaking

    CERN Document Server

    Demir, Durmus A; Langacker, Paul

    2007-01-01

    We demonstrate that Dirac neutrino masses in the experimentally preferred range are generated within supersymmetric gauge extensions of the Standard Model with a generalized supersymmetry breaking sector. If the usual superpotential Yukawa couplings are forbidden by the additional gauge symmetry (such as a U(1)'), effective Dirac mass terms involving the "wrong Higgs" field can arise either at tree level due to hard supersymmetry breaking fermion Yukawa couplings, or at one-loop due to nonanalytic or "nonholomorphic" soft supersymmetry breaking trilinear scalar couplings. As both of these operators are naturally suppressed in generic models of supersymmetry breaking, the resulting neutrino masses are naturally in the sub-eV range. The neutrino magnetic and electric dipole moments resulting from the radiative mechanism also vanish at one-loop order.

  10. Spontaneous chiral symmetry breaking in metamaterials

    Science.gov (United States)

    Liu, Mingkai; Powell, David A.; Shadrivov, Ilya V.; Lapine, Mikhail; Kivshar, Yuri S.

    2014-07-01

    Spontaneous chiral symmetry breaking underpins a variety of areas such as subatomic physics and biochemistry, and leads to an impressive range of fundamental phenomena. Here we show that this prominent effect is now available in artificial electromagnetic systems, enabled by the advent of magnetoelastic metamaterials where a mechanical degree of freedom leads to a rich variety of strong nonlinear effects such as bistability and self-oscillations. We report spontaneous symmetry breaking in torsional chiral magnetoelastic structures where two or more meta-molecules with opposite handedness are electromagnetically coupled, modifying the system stability. Importantly, we show that chiral symmetry breaking can be found in the stationary response of the system, and the effect is successfully demonstrated in a microwave pump-probe experiment. Such symmetry breaking can lead to a giant nonlinear polarization change, energy localization and mode splitting, which provides a new possibility for creating an artificial phase transition in metamaterials, analogous to that in ferrimagnetic domains.

  11. Development of Adolescent Relationships

    OpenAIRE

    Goede, I.H.A. de

    2009-01-01

    This dissertation on “Development of Adolescent Relationships” addresses relationships with parents, friends, and romantic partners in adolescence from a developmental perspective. By studying both parent-adolescent relationships and peer relationships at the same time, as well as interrelations between these types of relationships, this dissertation provides more information on the processes taking place in relationships during adolescence. Findings indicate that parent-adolescent relationsh...

  12. Relativistic theory of string breaking in QCD

    CERN Document Server

    Simonov, Yu A

    2011-01-01

    The QCD string breaking due to quark pair creation in the vacuum confining field, possibly accompanied by vector, scalar or Nambu-Goldstone bosons, is studied nonperturbatively. The scalar light pair creation vertex occurs due to chiral symmetry breaking and has a confining form, which is computed explicitly together with subleading vector contributions. Dependence on light quark mass and flavor is specifically studied. The dominant scalar term is in good agreement with the $^3P_0$ model and experimental data.

  13. AIR LOAD BREAK SWITCH DESIGN PARAMETERS

    OpenAIRE

    Støa-Aanensen, Nina Sasaki

    2015-01-01

    Current interruption is vital in the power system, as this makes it possible to control the use of different loads, change the grid configuration, and minimize damage when faults occur. This thesis presents a study of the different switch design and test circuit parameters involved in medium voltage air load break switching and how they affect the thermal interrupting capability. Mediumvoltage load break switches are common in the distribution grid, and are a cheaper option ...

  14. Grand unification with large supersymmetry breaking

    International Nuclear Information System (INIS)

    General criteria are given for the magnitudes of mass splittings between supersymmetric partners compatible with the desired hierarchy of mass scales in GUTs. These splittings arise naturally when masses are generated radiatively from a Higgs sector breaking supersymmetry through the O'Raifeartaigh mechanism (Nucl. Phys; B96:331 (1975)). Explicit GUTs are constructed in which the supersymmetry breaking scale may easily be as large as the Planck mass. (author)

  15. Dirac Neutrino Masses from Generalized Supersymmetry Breaking

    OpenAIRE

    Demir, Durmus A.; Everett, Lisa L.; Langacker, Paul

    2007-01-01

    We demonstrate that Dirac neutrino masses in the experimentally preferred range are generated within supersymmetric gauge extensions of the Standard Model with a generalized supersymmetry breaking sector. If the usual superpotential Yukawa couplings are forbidden by the additional gauge symmetry (such as a U(1)'), effective Dirac mass terms involving the "wrong Higgs" field can arise either at tree level due to hard supersymmetry breaking fermion Yukawa couplings, or at one-loop due to nonana...

  16. A random fuse model for breaking processes

    OpenAIRE

    de Arcangelis, L.; Redner, S.; Herrmann, H. J.

    1985-01-01

    We introduce and study a simple idealized model to describe breaking processes by analysing the current-carrying properties of a random network consisting of insulators and fuses. By increasing the value of the external voltage applied across the network, a sequence of fuses will « burn out » and change irreversible into insultating bonds. This process terminates when a conducting path no longer exists in the network. We monitor several basic quantities during this breaking process, such as t...

  17. Yet another symmetry breaking to be discovered

    CERN Document Server

    Yoshimura, M

    2016-01-01

    The discovery of spontaneous symmetry breaking in particle physics was the greatest contribution in Nambu's achievements. There is another class of symmetries that exist in the low energy nature, yet is doomed to be broken at high energy, due to a lack of protection of the gauge symmetry. I shall review our approach to search for this class of symmetry breaking, the lepton number violation linked to generation of the matter-antimatter asymmetry in our universe.

  18. Dark matter from dynamical SUSY breaking

    OpenAIRE

    Fan, JiJi; Thaler, Jesse; Wang, Lian-Tao

    2010-01-01

    We consider explicit models of dynamical supersymmetry breaking where dark matter is a 10 – 100 TeV strongly-interacting composite state carrying no standard model quantum numbers. These constructions are simple variants of well-known supersymmetry breaking mechanisms, augmented to allow for a large “flavor” symmetry. Dark matter is the lightest composite modulus charged under this symmetry and is a viable cold dark matter candidate with a thermal relic abundance. This is an at...

  19. Holographic realization of gauge mediated supersymmetry breaking

    CERN Document Server

    Skenderis, Kostas

    2012-01-01

    The general gauge mediation scenario provides a framework in which properties of a visible sector with soft supersymmetry breaking are computed from current correlation functions in the supersymmetry breaking hidden sector. In this paper we will use holography to model strongly coupled hidden sectors by weakly curved geometries and describe how the current correlators relevant for general gauge mediation are computed by holographic methods. We illustrate the general setup by a toy example which captures most of the relevant features.

  20. Chimera Death: Symmetry Breaking in Dynamical Networks

    OpenAIRE

    Zakharova, Anna; Kapeller, Marie; Schöll, Eckehard

    2014-01-01

    For a network of generic oscillators with nonlocal topology and symmetry-breaking coupling we establish novel partially coherent inhomogeneous spatial patterns, which combine the features of chimera states (coexisting incongruous coherent and incoherent domains) and oscillation death (oscillation suppression), which we call chimera death. We show that due to the interplay of nonlocality and breaking of rotational symmetry by the coupling two distinct scenarios from oscillatory behavior to a s...

  1. Yet another symmetry breaking to be discovered

    Science.gov (United States)

    Yoshimura, M.

    2016-07-01

    The discovery of spontaneous symmetry breaking in particle physics was the greatest contribution in Nambu's achievements. There is another class of symmetries that exist in low-energy nature, yet is doomed to be broken at high energy, due to a lack of protection of the gauge symmetry. I shall review our approach to searching for this class of symmetry breaking, the lepton number violation linked to the generation of the matter-antimatter asymmetry in our universe.

  2. Iron Deficiency in Adolescents and Young Adults.

    Science.gov (United States)

    Risser, William L.; Risser, Jan M. H.

    1990-01-01

    Reviews the prevalence, natural history, causes, impact on performance, diagnosis, and treatment of iron deficiency in adolescent and young adult athletes. All athletes should be screened and treated. The best diagnosis involves determining serum ferritin and hemoglobin levels. Treatment requires therapeutic doses of oral ferrous iron for several…

  3. Break! On the unpleasant, the marginal, the taboo, and the controversial in Norwegian museums

    Directory of Open Access Journals (Sweden)

    Liv Ramskjaer

    2014-10-01

    Full Text Available This paper explores the programme entitled Break, which was launched within a grouping of Norwegian museums in 2003. Break emerged in the context of a more critical approach to museum practice and their ways of dealing with controversial pasts in the wake of the new museology. A central goal for Break has been to promote a shift from the presentation of conventionally treated narratives in order to focus on areas that are marginal, hidden, contested and regarded as unpleasant. The programme has aimed to strengthen museums as active social institutions that are able to engage successfully with current issues and to stimulate serious reflection among visitors. While the concern to avoid making waves or drawing negative publicity often hinders museums from tackling controversial issues, Break is distinctive in that the initiative came not from within the institutional setting of the museum but among certain authorities in Norway that served as its leading agents. In this short reflection on Break, I explore two key questions: How has Break encouraged new approaches to difficult and, in particular, marginalised histories; and what representations have ensued from it that may help to continue problematising museum collections in Norway and stimulating critical engagement.

  4. Adolescent witnesses in cases of teen dating violence: An analysis of peer responses

    OpenAIRE

    Helena Bonache; Francisca Exposito; Josefa Ruiz

    2010-01-01

    Gender violence is a serious problem that also affects the adolescent population (González & Santana, 2001). The victims of such violence in adolescence, should they seek help, rely primarily on their peers and rarely report it to adults (Weisz et al., 2007). The responses or reactions of avoidance, minimization or protection that their peers may have contribute to the victim maintaining or breaking the "unhealthy" relationship. An experimental study was designed to examine the reactions of a...

  5. Different repair kinetic of DSBs induced by mitomycin C in peripheral lymphocytes of obese and normal weight adolescents.

    Science.gov (United States)

    Azzarà, Alessia; Pirillo, Chiara; Giovannini, Caterina; Federico, Giovanni; Scarpato, Roberto

    2016-07-01

    In 2013, 42 million children under the age of 5 years were overweight or obese. In the context of obesity, we recently showed that (1) peripheral lymphocytes of obese children/adolescents had an 8-fold increase in double strand breaks (DSBs), expressed as g-H2AX foci, than normal weight adolescents, and (2) 30% of the damage was retained into chromosome mutations. Thus, we investigated DSBs repair efficiency in a group of obese adolescents assessing the kinetic of H2AX phosphorylation in mitomycin C (MMC)-treated lymphocytes harvested 2 h- or 4 h-post mutagen treatment. According to our previous studies, these harvesting times represent the peak of DSBs induction and the time in which an appreciable DSBs reduction was observed. In addition, we evaluated the expression of the high mobility group box-1 protein (HMGB1), a chromatin remodelling protein involved in DSBs repair and obesity. Compared to normal weight adolescents, obese subjects 1) showed higher levels of g-H2AX foci at either 2 h- (0.239±0.041 vs. 0.473±0.048, P=0.0016) or 4 h- (0.150±0.026 vs. 0.255±0.030, P=0.0198) post mutagen treatment, and 2) have repaired a greater amount of the initial lesions (0.088±0.033 vs. 0.218±0.045, P=0.0408). Concordantly, 1) HMGB1 levels of obese individuals increased and decreased at 2h- or 4 h-post mutagen treatment, respectively, and 2) the opposite occurred for the normal weight adolescents where the protein was down-expressed at 2h and over-expressed at 4h. In conclusion, lymphocytes of obese and normal weight adolescents showed a distinct temporal kinetic of repairing MMC-induced DSBs, together with a different expression of HMGB1. The finding that obesity may modulate the repair of DNA damage induced in lymphocytes by genotoxic agents should be confirmed by further experiments. PMID:27174706

  6. Sport injuries in adolescents.

    Science.gov (United States)

    Habelt, Susanne; Hasler, Carol Claudius; Steinbrück, Klaus; Majewski, Martin

    2011-09-01

    In spite of the wide range of injuries in adolescents during sports activities, there are only a few studies investigating the type and frequency of sport injuries in puberty. However, this information may help to prevent, diagnose and treat sports injuries among teens. 4468 injuries in adolescent patients were treated over a ten year period of time: 66,97% were boys and 32.88% girls. The most frequent sports injuries were football (31.13%) followed by handball (8.89%) and sports during school (8.77%). The lower extremity was involved in 68.71% of the cases. Knee problems were seen in 29.79% of the patients; 2.57% spine and 1.99% head injuries. Injuries consisted primarily of distortions (35.34%) and ligament tears (18.76%); 9,00% of all injuries were fractures. We found more skin wounds (6:1) and fractures (7:2) in male patients compared to females. The risk of ligament tears was highest during skiing. Three of four ski injuries led to knee problems. Spine injuries were observed most often during horse riding (1:6). Head injuries were seen in bicycle accidents (1:3). Head injuries were seen in male patients much more often then in female patients (21:1). Fractures were noted during football (1:9), skiing (1:9), inline (2:3), and during school sports (1:11). Many adolescents participate in various sports. Notwithstanding the methodological problems with epidemiological data, there is no doubt about the large number of athletes sustain musculoskeletal injuries, sometimes serious. In most instances, the accident does not happened during professional sports and training. Therefore, school teachers and low league trainer play an important role preventing further accidence based on knowledge of individual risk patterns of different sports.It is imperative to provide preventive medical check-ups, to monitor the sport-specific needs for each individual sports, to observe the training skills as well as physical fitness needed and to evaluation coaches education. PMID

  7. Sport injuries in adolescents

    Directory of Open Access Journals (Sweden)

    Susanne Habelt

    2011-11-01

    Full Text Available In spite of the wide range of injuries in adolescents during sports activities, there are only a few studies investigating the type and frequency of sport injuries in puberty. However, this information may help to prevent, diagnose and treat sports injuries among teens. 4468 injuries in adolescent patients were treated over a ten year period of time: 66,97% were boys and 32.88% girls. The most frequent sports injuries were football (31.13% followed by handball (8.89% and sports during school (8.77%. The lower extremity was involved in 68.71% of the cases. Knee problems were seen in 29.79% of the patients; 2.57% spine and 1.99% head injuries. Injuries consisted primarily of distortions (35.34% and ligament tears (18.76%; 9,00% of all injuries were fractures. We found more skin wounds (6:1 and fractures (7:2 in male patients compared to females. The risk of ligament tears was highest during skiing. Three of four ski injuries led to knee problems. Spine injuries were observed most often during horse riding (1:6. Head injuries were seen in bicycle accidents (1:3. Head injuries were seen in male patients much more often then in female patients (21:1. Fractures were noted during football (1:9, skiing (1:9, inline (2:3, and during school sports (1:11. Many adolescents participate in various sports. Notwithstanding the methodological problems with epidemiological data, there is no doubt about the large number of athletes sustain musculoskeletal injuries, sometimes serious. In most instances, the accident does not happened during professional sports and training. Therefore, school teachers and low league trainer play an important role preventing further accidence based on knowledge of individual risk patterns of different sports. It is imperative to provide preventive medical check-ups, to monitor the sport-specific needs for each individual sports, to observe the training skills as well as physical fitness needed and to evaluation coaches education.

  8. Apophyseal damage in adolescent athlete

    International Nuclear Information System (INIS)

    The increasing demands on the adolescent athlete in high perfomance sports puts high biomechanical stress on the growing structures of the active and passive locomotor system. The ''growing factor'' itself increases stretching forces on tendon insertions, which are often overloaded when a physical demanding sport is performed additionally. The apophysis is an ossification nucleus near the tendon insertion, which appears before the growing age resumes and these apophysis finally fuses with the adjacent bone. The tensile forces from vigorous sports activity leads to a chronic or acute avulsion of the ossifying tendon insertion. The radiological appearance of this apophyseal damage with ossification and osteolytic processes is sometimes difficult with respect to differential diagnoses. Apophyseal impairment is associated with pain, tenderness to palpation and decreased muscle function. If it is not diagnosed and treated properly it can lead to end of career in many adolescent athletes. (orig.)

  9. Distúrbios psiquiátricos, tentativas de suicídio, lesões e envenenamento em adolescentes atendidos em uma unidade de emergência, Ribeirão Preto, São Paulo, 1988-1993 Psychiatric disorders, suicide attempts, lesions and poisoning among adolescents treated in an emergency room, Ribeirão Preto, São Paulo, 1988-1993

    Directory of Open Access Journals (Sweden)

    Ana Maria Fortaleza Teixeira

    1997-09-01

    Full Text Available Trata-se de um estudo epidemiológico acerca da ocorrência de distúrbios psiquiátricos e outros relacionados, segundo o Código Internacional de Doenças, em adolescentes atendidos no setor de urgências psiquiátricas de um hospital-escola de Ribeirão Preto, São Paulo, Brasil, durante o período de 1988 a 1993. Os adolescentes representaram 23% dos atendimentos no período. No sexo feminino, predominaram os Transtornos Neuróticos (300, Suicídio e Lesões Auto-Infligidas (E950-E959 e Psicoses Esquizofrênicas (295. No sexo masculino, sobressaíram-se os Quadros Relacionados a Álcool e Drogas (291, 292, 303, 304, 305, Psicoses Esquizofrênicas (295 e Transtornos Neuróticos (300. Dentre os adolescentes, predominaram as faixas 20 a 24 anos e 15 a 19 anos, consecutivamente.An epidemiological study was conducted to determine the occurrence of psychiatric and related disorders, according to the International Classification of Diseases, among adolescents treated in an emergency room of a teaching hospital in Ribeirão Preto, São Paulo, Brazil from 1988 to 1993. Adolescents studied represented 23% of the cases treated during this period. Neurotic Disorders (300, Suicide and self-inflicted Lesions (E950-E959, and Schizophrenic Psychoses (295 predominated among females. Signs and Symptoms related to alcohol and drugs (291, 292, 303, 304, 305, Schizophrenic Psychoses (295 and Neurotic Disorders (300 predominated among males. Adolescents studied were predominantly in the 20 to 24 and 15 to 19 year range, in this order.

  10. Adapting Cognitive-Behavioral Therapy for Depressed Adolescents Exposed to Interpersonal Trauma: A Case Study With Two Teens

    OpenAIRE

    DePrince, Anne P.; Shirk, Stephen R.

    2012-01-01

    A substantial body of evidence indicates that interpersonal trauma increases risk for adolescent and adult depression. Findings from 4 clinical trials for adolescent depression show poorer response to standard cognitive-behavioral therapy (CBT) among depressed adolescents with a trauma history than youth without such a history. This paper reports on the development of a modified CBT (mCBT) protocol that has been adapted for treating depressed adolescents who have been exposed to traumatic int...

  11. Effects of γ-hydroxybutyric acid on spatial learning and memory in adolescent and adult female rats

    OpenAIRE

    Sircar, Ratna; Basak, Ashim; Sircar, Debashish; Wu, Li-Cheng

    2010-01-01

    γ-hydroxybutyric acid (GHB) has been reported to disrupt spatial learning and memory in adolescent male rats. The present study was undertaken to determine the effects of GHB on the acquisition of spatial memory in adolescent female rats, and to investigate age specificity of the behavioral impairments. Adolescent female rats were subjected to repeated GHB or saline administrations, and tested in the Morris water maze. Compared to age-matched saline controls, adolescent GHB-treated rats took ...

  12. Meanings intrafamilial sexual abuse for female adolescents

    Directory of Open Access Journals (Sweden)

    Juliana Hilario Maranhão

    2014-12-01

    Full Text Available This article came from the monographic study “Resilience and Sexual Violence: a study of adolescents victimized by sexual abuse assistance” (MARANHÃO, 2008, in which was investigated the building resilience in victimized adolescents. Resilience is characterized as overcoming adversity, setting up as something procedural, promoted by the interaction of personal and collective protection, in particular context of risk or social vulnerability. We made the trimming about the meanings and feelings of sexual victimization within the family from the perception of adolescents between 12 and 16 years of age that received care in a Specialized Reference Social Assistance in 2010. The research is qualitative, having as theoretical-methodological referential the Historic-Cultural Theory. Data collection was used by semi-structured interview. We realize that the profile of the victims are set up by females, the beginning of sexual abuse occurred between childhood and preadolescence. The profile of perpetrators are men, adults, acting the role of the stepfather, father and uncle. Despite an abject sense, adolescents could not break the cycle of violence. Friends, extended family, and the work of professionals emerged as support for the redefinition of the abusive relationships.

  13. Modelling oil price volatility with structural breaks

    International Nuclear Information System (INIS)

    In this paper, we provide two main innovations: (i) we analyze oil prices of two prominent markets namely West Texas Intermediate (WTI) and Brent using the two recently developed tests by Narayan and Popp (2010) and Liu and Narayan, 2010 both of which allow for two structural breaks in the data series; and (ii) the latter method is modified to include both symmetric and asymmetric volatility models. We identify two structural breaks that occur in 1990 and 2008 which coincidentally correspond to the Iraqi/Kuwait conflict and the global financial crisis, respectively. We find evidence of persistence and leverage effects in the oil price volatility. While further extensions can be pursued, the consideration of asymmetric effects as well as structural breaks should not be jettisoned when modelling oil price volatility. - Highlights: ► We analyze oil price volatility using NP (2010) and LN (2010) tests. ► We modify the LN (2010) to account for leverage effects in oil price. ► We find two structural breaks that reflect major global crisis in the oil market. ► We find evidence of persistence and leverage effects in oil price volatility. ► Leverage effects and structural breaks are fundamental in oil price modelling.

  14. The characteristics of serious suicide attempters in Japanese adolescents- comparison study between adolescents and adults

    Directory of Open Access Journals (Sweden)

    Kawashima Yoshitaka

    2012-11-01

    Full Text Available Abstract Background Suicide is the leading cause of death among Japanese adolescents, and they may commit suicide differently from adults. However, there are few studies in medical-based data concerning adolescent patients seriously attempting suicide. We aimed to explore the characteristics of serious suicide attempts in Japanese adolescents, comparing them with those in adults. Methods We investigated adolescents who seriously attempted suicide and were treated at the Critical Care Medical Center (CCMC of Nippon Medical School Hospital between 2000 and 2010, and we compared them with adult suicide attempters treated during 2009. We retrospectively studied medical records and collected clinical data and socio-demographic factors, including age, sex, psychiatric symptoms or diagnosis, methods of suicide attempt, motives for suicide attempt, previous deliberate self-harm, previous psychiatric history, parent loss experience, and previous psychiatric history in the family. Results Adolescent attempters were 15 males and 44 females, 13 to 18 years old (mean 16.39. Adult attempters were 37 males and 65 females, 19 to 79 years old (mean 39.45. In comparison to adult attempters, adolescent attempters were more frequently diagnosed with Borderline Personality Disorder (BPD, had more school problems and parent loss experience, but they had less financial problems. Gender differences between adolescents and adults were examined, and male adolescent attempters were found to be more frequently diagnosed with schizophrenia and had less financial problems than their adult counterparts, while female adolescent attempters were more frequently diagnosed with BPD, had more school problems and parent loss, but they had less previous psychiatric history than their adult counterparts. Conclusions Our findings indicated that adolescent attempters were more frequently diagnosed with BPD and had more school problems and parent loss experience but had less financial

  15. Calculation of the limiting CESSAR Feedwater Line-Break and Steam Line-Break transients

    International Nuclear Information System (INIS)

    Argonne National Laboratory (ANL), under contract to the Nuclear Regulatory Commission, performed audit calculations of the limiting Feedwater Line Break (FLB) and Steam Line Break (SLB) transients presented in the CESSAR FSAR. The results of the FLB and SLB calculations are discussed

  16. Break-glass handling exceptional situations in access control

    CERN Document Server

    Petritsch, Helmut

    2014-01-01

    Helmut Petritsch describes the first holistic approach to Break-Glass which covers the whole life-cycle: from access control modeling (pre-access), to logging the security-relevant system state during Break-Glass accesses (at-access), and the automated analysis of Break-Glass accesses (post-access). Break-Glass allows users to override security restrictions in exceptional situations. While several Break-Glass models specific to given access control models have already been discussed in research (e.g., extending RBAC with Break-Glass), the author introduces a generic Break-Glass model. The pres

  17. Marginal Breaking of Conformal SUSY QCD

    CERN Document Server

    Cleary, Kevin F

    2015-01-01

    We provide an example of a 4D theory that exhibits the Contino-Pomarol-Rattazzi mechanism, where breaking conformal symmetry by an almost marginal operator leads to a light pseudo-Goldstone boson, the dilaton, and a parametrically suppressed contribution to vacuum energy. We consider SUSY QCD at the edge of the conformal window and break conformal symmetry by weakly gauging a subgroup of the flavor symmetry. Using Seiberg duality we show that for a range of parameters the singlet meson in the dual theory reaches the unitarity bound, however, this theory does not have a stable vacuum. We stabilize the vacuum with soft breaking terms, compute the mass of the dilaton, and determine the range of parameters where the leading contribution to the dilaton mass is from the almost marginal coupling.

  18. Supersymmetry breaking as a quantum phase transition

    International Nuclear Information System (INIS)

    We explore supersymmetry breaking in the light of a rich fixed-point structure of two-dimensional supersymmetric Wess-Zumino models with one supercharge using the functional renormalization group. We relate the dynamical breaking of supersymmetry to a renormalization group relevant control parameter of the superpotential which is a common relevant direction of all fixed points of the system. Supersymmetry breaking can thus be understood as a quantum phase transition analogous to similar transitions in correlated fermion systems. Supersymmetry gives rise to a new superscaling relation between the critical exponent associated with the control parameter and the anomalous dimension of the field - a scaling relation which is not known in standard spin systems.

  19. Supersymmetry breaking as a quantum phase transition

    CERN Document Server

    Gies, Holger; Wipf, Andreas

    2009-01-01

    We explore supersymmetry breaking in the light of a rich fixed-point structure of two-dimensional supersymmetric Wess-Zumino models with one supercharge using the functional renormalization group (RG). We relate the dynamical breaking of supersymmetry to an RG relevant control parameter of the superpotential which is a common relevant direction of all fixed points of the system. Supersymmetry breaking can thus be understood as a quantum phase transition analogously to similar transitions in correlated fermion systems. Supersymmetry gives rise to a new superscaling relation between the critical exponent associated with the control parameter and the anomalous dimension of the field -- a scaling relation which is not known in standard spin systems.

  20. Dynamical supersymmetry breaking on quantum moduli spaces

    International Nuclear Information System (INIS)

    Supersymmetry breaking by the quantum deformation of a classical moduli space is considered. A simple, non-chiral, renormalizable model is presented to illustrate this mechanism. The well-known, chiral, SU(3) x SU(2) model and its generalizations are shown to break supersymmetry by this mechanism in the limit Λ2>>Λ3. Other supersymmetry breaking models, with classical flat directions that are only lifted quantum mechanically, are presented. Finally, by integrating in vector matter, the strongly coupled region of chiral models with a dynamically generated superpotential is shown to be continuously connected to a weakly coupled description in terms of confined degrees of freedom, with supersymmetry broken at tree level. (orig.)

  1. Workshop on electroweak symmetry breaking: proceedings

    International Nuclear Information System (INIS)

    A theoretical workshop on electroweak symmetry breaking at the Superconducting Supercollider was held at Lawrence Berkeley Laboratory, June 4-22, 1984. The purpose of the workshop was to focus theoretical attention on the ways in which experimentation at the SSC could reveal manifestations of the phenomenon responsible for electroweak symmetry breaking. This issue represents, at present, the most compelling scientific argument for the need to explore the energy region to be made accessible by the SSC, and a major aim of the workshop was to involve a broad cross section of particle theorists in the ongoing process of sharpening the requirements for both accelerator and detector design that will ensure detection and identification of meaningful signals, whatever form the electroweak symmetry breaking phenomenon should actually take. Separate entries were prepared for the data base for the papers presented

  2. Enhanced breaking of heavy quark spin symmetry

    CERN Document Server

    Guo, Feng-Kun; Shen, Cheng-Ping

    2014-01-01

    Heavy quark spin symmetry is useful to make predictions on ratios of decay or production rates of systems involving heavy quarks. The breaking of spin symmetry is generally of the order of $O({\\Lambda_{\\rm QCD}/m_Q})$, with $\\Lambda_{\\rm QCD}$ the scale of QCD and $m_Q$ the heavy quark mass. In this paper, we propose a new mechanism to enhance the spin symmetry breaking. Taking the decays of the $\\Upsilon(10860)$ into the $\\chi_{bJ}\\omega\\, (J=0,1,2)$ as an example, we show that a small $S$- and $D$-wave mixing can induce a significant breaking of the spin symmetry relations for the ratios of the branching fractions of these decays, owing to an enhancement of the decays of the $D$-wave component due to nearby coupled channels.

  3. A break in the obesity epidemic?

    DEFF Research Database (Denmark)

    Visscher, T L S; Heitmann, B L; Rissanen, A;

    2015-01-01

    epidemic. However, follow-ups of short duration may, in part, explain the apparent break or decrease in the obesity epidemic. On the other hand, a single focus on body mass index (BMI) ⩾25 or ⩾30 kg m(-)(2) is likely to mask a real increase in the obesity epidemic. And, in both children and adults, trends......Recent epidemiologic papers are presenting prevalence data suggesting breaks and decreases in obesity rates. However, before concluding that the obesity epidemic is not increasing anymore, the validity of the presented data should be discussed more thoroughly. We had a closer look...... into the literature presented in recent reviews to address the major potential biases and distortions, and to develop insights about how to interpret the presented suggestions for a potential break in the obesity epidemic. Decreasing participation rates, the use of reported rather than measured data and small sample...

  4. Workshop on electroweak symmetry breaking: proceedings

    Energy Technology Data Exchange (ETDEWEB)

    Hinchliffe, I. (ed.)

    1984-10-01

    A theoretical workshop on electroweak symmetry breaking at the Superconducting Supercollider was held at Lawrence Berkeley Laboratory, June 4-22, 1984. The purpose of the workshop was to focus theoretical attention on the ways in which experimentation at the SSC could reveal manifestations of the phenomenon responsible for electroweak symmetry breaking. This issue represents, at present, the most compelling scientific argument for the need to explore the energy region to be made accessible by the SSC, and a major aim of the workshop was to involve a broad cross section of particle theorists in the ongoing process of sharpening the requirements for both accelerator and detector design that will ensure detection and identification of meaningful signals, whatever form the electroweak symmetry breaking phenomenon should actually take. Separate entries were prepared for the data base for the papers presented.

  5. Large eddy simulation of breaking waves

    DEFF Research Database (Denmark)

    Christensen, Erik Damgaard; Deigaard, Rolf

    2001-01-01

    A numerical model is used to simulate wave breaking, the large scale water motions and turbulence induced by the breaking process. The model consists of a free surface model using the surface markers method combined with a three-dimensional model that solves the flow equations. The turbulence is...... incoming waves are specified by a flux boundary condition. The waves are approaching in the shore-normal direction and are breaking on a plane, constant slope beach. The first few wave periods are simulated by a two-dimensional model in the vertical plane normal to the beach line. The model describes the...... steepening and the overturning of the wave. At a given instant, the model domain is extended to three dimensions, and the two-dimensional flow field develops spontaneously three-dimensional flow features with turbulent eddies. After a few wave periods, stationary (periodic) conditions are achieved. The...

  6. U(1) mediation of flux supersymmetry breaking

    International Nuclear Information System (INIS)

    We study the mediation of supersymmetry breaking triggered by background fluxes in Type II string compactifications with N = 1 supersymmetry. The mediation arises due to an U(1) vector multiplet coupling to both a hidden supersymmetry breaking flux sector and a visible D-brane sector. The required internal manifolds can be constructed by non-Kaehler resolutions of singular Calabi-Yau manifolds. The effective action encoding the U(1) coupling is then determined in terms of the global topological properties of the internal space. We investigate suitable local geometries for the hidden and visible sector in detail. This includes a systematic study of orientifold symmetries of del Pezzo surfaces realized in compact geometries after geometric transition. We construct compact examples admitting the key properties to realize flux supersymmetry breaking and U(1) mediation. Their toric realization allows us to analyze the geometry of curve classes and confirm the topological connection between the hidden and visible sector.

  7. Weyl geometric gravity and "breaking" of electroweak symmetry

    CERN Document Server

    Scholz, Erhard

    2011-01-01

    A Weyl geometric scale covariant approach to gravity due to Omote, Dirac, and Utiyama (1971ff) is reconsidered. It can be extended to the electroweak sector of elementary particle fields, taking into account their basic scaling freedom. Already Cheng (1988) indicated that electroweak symmetry breaking, usually attributed to the Higgs field with a boson expected at $0.1 - 1 \\,TeV$, may be due to a coupling between Weyl geometric gravity and electroweak interactions. Weyl geometry seems to be well suited for treating questions of elementary particle physics, which relate to scale invariance and its "breaking". This setting suggests the existence of a scalar field boson at the surprisingly low energy of $\\sim 1\\, eV$. That may appear unlikely; but, as a payoff, the naturalness problem of the standard Higgs field seems to become immaterial. Moreover, the acquirement of mass arises as a result of coupling to gravity in agreement with the understanding of mass as the gravitational charge of fields. Finally, the pot...

  8. Coupled simulation of steam line break accident

    International Nuclear Information System (INIS)

    The steam line break is a PWR type reactor design accident, which concerns coupled physical phenomena. To control these problems simulation are needed to define and validate the operating procedures. The benchmark OECD PWR MSLB (Main Steam Line Break) has been proposed by the OECD to validate the feasibility and the contribution of the multi-dimensional tools in the simulation of the core transients. First the benchmark OECD PWR MSLB is presented. Then the analysis of the three exercises (system with pinpoint kinetic, three-dimensional core and whole system with three-dimensional core) are discussed. (A.L.B.)

  9. Polarimetric contrast microscopy by orthogonality breaking

    International Nuclear Information System (INIS)

    We report the design and first implementation of an active polarimetric imaging system based on the recently introduced concept of polarimetric sensing by orthogonality breaking, which involves a specific crossed-polarization dual-frequency illumination. We describe the laser source architecture and microscope set-up devoted to visible imaging at 488 nm, as well as the specific homodyne detection chain required for orthogonality breaking measurements. The first polarimetric images obtained with this non-conventional approach are presented. The polarimetric contrasts observed validate the polarimetric sensitivity of the technique. (fast track communication)

  10. R-Parity Breaking in Minimal Supergravity

    CERN Document Server

    Díaz, M A

    1997-01-01

    We consider the Minimal Supergravity Model with universality of scalar and gaugino masses plus an extra bilinear term in the superpotential which breaks R-Parity and lepton number. We explicitly check the consistency of this model with the radiative breaking of the electroweak symmetry. A neutrino mass is radiatively induced, and large Higgs-Lepton mixings are compatible with its experimental bound. We also study briefly the lightest Higgs mass. This one-parameter extension of SUGRA-MSSM is the simplest way of introducing R-parity violation.

  11. Variations on Minimal Gauge Mediated Supersymmetry Breaking

    CERN Document Server

    Dine, Michael; Shirman, Yu; Dine, Michael; Nir, Yosef; Shirman, Yuri

    1997-01-01

    We study various modifications to the minimal models of gauge mediated supersymmetry breaking. We argue that, under reasonable assumptions, the structure of the messenger sector is rather restricted. We investigate the effects of possible mixing between messenger and ordinary squark and slepton fields and, in particular, violation of universality. We show that acceptable values for the $\\mu$ and $B$ parameters can naturally arise from discrete, possibly horizontal, symmetries. We claim that in models where the supersymmetry breaking parameters $A$ and $B$ vanish at tree level, $\\tan\\beta$ could be large without fine tuning. We explain how the supersymmetric CP problem is solved in such models.

  12. The experimental investigation of supersymmetry breaking

    International Nuclear Information System (INIS)

    If Nature is supersymmetric at the weak interaction scale, what can we hope to learn from experiments on supersymmetric particles? The most mysterious aspect of phenomenological supersymmetry is the mechanism of spontaneous supersymmetry breaking. This mechanism ties the observable pattern of supersymmetric particle masses to aspects of the underlying unified theory at very small distance scales. In this article, I will discuss a systematic experimental program to determine the mechanism of supersymmetry breaking. Both pp and e+e- colliders of the next generation play an essential role

  13. Chiral symmetry breaking in lattice electrodynamics

    International Nuclear Information System (INIS)

    Chiral symmetry breaking is studied in lattice quantum electrodynamics in the quenched approximation by computer-simulation methods. Simulations at zero temperature show that in non-zero for all couplings e2 greater than a critical value e2/sub c/. The sensitivity of to short-distance features of the lattice Action is studied by simulating variant gauge Actions. Simulations on asymmetric lattices do not reveal significant temperature dependence in the symmetry-breaking dynamics. Subtle effects and limitations of quenched calculations are discussed

  14. Effective dissipation: breaking time-reversal symmetry

    CERN Document Server

    Brown, Aidan I

    2016-01-01

    At molecular scales, fluctuations play a significant role and prevent biomolecular processes from always proceeding in a preferred direction, raising the question of how limited amounts of free energy can be dissipated to obtain directed progress. We examine the system and process characteristics that efficiently break time-reversal symmetry at fixed energy loss; in particular for a simple model of a molecular machine, an intermediate energy barrier produces unusually high asymmetry for a given dissipation. Such insight into symmetry-breaking factors that produce particularly high time asymmetry suggests generalizations to a broader class of systems.

  15. Chiral Symmetry Breaking from Center Vortices

    CERN Document Server

    Höllwieser, Roman; Schweigler, Thomas; Heller, Urs M

    2014-01-01

    We analyze the creation of near-zero modes from would-be zero modes of various topological charge contributions from classical center vortices in SU(2) lattice gauge theory. We show that colorful spherical vortex and instanton configurations have very similar Dirac eigenmodes and also vortex intersections are able to give rise to a finite density of near-zero modes, leading to chiral symmetry breaking via the Banks-Casher formula. We discuss the influence of the magnetic vortex fluxes on quarks and how center vortices may break chiral symmetry.

  16. Encyclopedia of adolescence

    NARCIS (Netherlands)

    Brown, B.B.; Prinstein, M.J.

    2011-01-01

    The period of adolescence involves growth, adaptation, and dramatic reorganization in almost every aspect of social and psychological development. The Encyclopedia of Adolescence offers an exhaustive and comprehensive review of current theory and research findings pertaining to this critical decade

  17. Post-Adolescent Issues

    Science.gov (United States)

    Search COPING & HEALING CARING FOR A CHILD: POST-ADOLESCENT ISSUES As your child reaches adulthood, there will ... intake. New issues that you and your post adolescent child may want to discus together with his/ ...

  18. Influence of night-breaks on flowering and phytohormones content in Hyoscyamus niger L.

    Directory of Open Access Journals (Sweden)

    Jan Kopcewicz

    2014-02-01

    Full Text Available Night-breaks caused both stimulated shoot growth and caused formation of flowers as well as a general increase in the content of phytohormones in leaves of the long-day plant Hyoscyamus niger L. At the time of flower formation in night-break treated plants, new gibberellin-like substances also appear. The results show that night-breaks cause similar changes in the phytohormones content as a long inductive photoperiod. It may be assumed that independently of the way of induction, the generative differentiation of long-day plants is always accompanied by a general increase in the amount of endogenous hormones and the appearance of new gibberellins. These results suggest the possibility of a morphogenetic role of hormones, especially gibberellins, in the phenomena of flower formation and differentiation.

  19. Effect of the caffeine on treated and non-treated plasmid DNA with stannic chloride

    International Nuclear Information System (INIS)

    Caffeine, a methilxantine drug is a component of coffee, tea, stimulants and other drinks. Caffeine inhibits phosphodiesterase leading to intracellular accumulation of cyclic AMP, blocks adenosine receptors, and increases the release of Ca2+. We have studied the possible effect of caffeine in DNA plasmid treated or not with stannous chloride (SnCl2). Previous evaluations of the effect of caffeine on the labeling of red blood cells and plasma proteins with technetium-99m have showed a decrease of % ATI in the insoluble fraction of plasma proteins. Samples of DNA were treated with SnCl2 (0 and 200μg/ml) in 0.8% agarose. SnCl2 has induced break on DNA and caffeine has not showed effect on the DNA. This indicates that caffeine does not eliminate the oxidant action of SnCl2 and does not promote break in isolated DNA plasmid. (author)

  20. Adolescent communication through music

    OpenAIRE

    Erdem, Cenk

    2011-01-01

    Famous nbsp; Greek Philosopher Plato states that young people need gymnastics for their bodies and music for their souls in his famous piece ldquo;The Republic rdquo; and any adult who observes the behaviours of adolescents can see that adolescents spend so much time with music and sports Lull shows that music functions as identification integration and expression for young adolescents So music preferences of adolescents may give some clues about their inner world nbsp; and personality traits...

  1. Group therapy for adolescents

    OpenAIRE

    Nada Hribar

    2001-01-01

    The group included adolescents from secondary school and some students. The group had weekly sessions or twice on mounth. The adolescents had varied simptoms: depressive, anxiety, psychosomatic disorders, learning difficulties, cunduct problems. All of adolescents were common on many problems in social interactions. The goal of therapeutic work were: to increase assertiveness skills and to reduce the anxious in social situations. The adolescents in group raised a self-esteem and developed som...

  2. Gifted Adolescents and Suicide.

    Science.gov (United States)

    Weisse, Dan E.

    1990-01-01

    Begins by presenting definitions of adolescence, suicide, and gifted, then goes on to examine issues related to suicide among gifted adolescents. Precipitating events for the gifted adolescent are identified, including perfectionism, disappointments, insecurities, career identity issues, and depression. Outlines warning signs and risk factors to…

  3. Adolescence and Mythology

    Science.gov (United States)

    Anastasopoulos, Dimitris; Soumaki, Eugenia; Anagnostopoulos, Dimitris

    2010-01-01

    The article begins with a brief exploration of the various aspects of adolescent's psychic qualities as these are described in Greek mythology. It is argued that myths are an integral part of the way that adolescence is perceived and myths play an important role in adolescents' psychic and external world, as well as in their mythological thinking.…

  4. Demystifying the Adolescent Brain

    Science.gov (United States)

    Steinberg, Laurence

    2011-01-01

    Understanding the nature of brain development in adolescence helps explain why adolescents can vacillate so often between mature and immature behavior. Early and middle adolescence, in particular, are times of heightened vulnerability to risky and reckless behavior because the brain's reward center is easily aroused, but the systems that control…

  5. Advances in understanding and treating ADHD

    Directory of Open Access Journals (Sweden)

    Hendricks Kaitlin

    2011-06-01

    Full Text Available Abstract Attention deficit hyperactivity disorder (ADHD is a neurocognitive behavioral developmental disorder most commonly seen in childhood and adolescence, which often extends to the adult years. Relative to a decade ago, there has been extensive research into understanding the factors underlying ADHD, leading to far more treatment options available for both adolescents and adults with this disorder. Novel stimulant formulations have made it possible to tailor treatment to the duration of efficacy required by patients, and to help mitigate the potential for abuse, misuse and diversion. Several new non-stimulant options have also emerged in the past few years. Among these, cognitive behavioral interventions have proven popular in the treatment of adult ADHD, especially within the adult population who cannot or will not use medications, along with the many medication-treated patients who continue to show residual disability.

  6. Operant Reinforcement with Structural Family Therapy in Treating Anorexia Nervosa

    Science.gov (United States)

    Perlman, Lawrence M.; Bender, Sheila S.

    1975-01-01

    The authors successfully treated two families in which the index patients were anorectic adolescent girls by combining structural family therapy with behavioral modification techniques. Phases which appear to be typical of the treatment are described. A discussion of the value of the operant reinforcement procedure in family therapy follows.…

  7. Stochastic properties of circuit breaking arcs

    Science.gov (United States)

    Rothhardt, L.

    1985-09-01

    Results are discussed for research work concerning the influence of cooling gas turbulence onto the breaker arc and the dielectric properties of the widely used cooling gases, air, and SF6, at elevated temperatures, both needed for numerical simulation of the breaking action.

  8. Symmetry Breaking for Black-Scholes Equations

    Institute of Scientific and Technical Information of China (English)

    YANG Xuan-Liu; ZHANG Shun-Li; QU Chang-Zheng

    2007-01-01

    Black-Scholes equation is used to model stock option pricing. In this paper, optimal systems with one to four parameters of Lie point symmetries for Black-Scholes equation and its extension are obtained. Their symmetry breaking interaction associated with the optimal systems is also studied. As a result, symmetry reductions and corresponding solutions for the resulting equations are obtained.

  9. Symmetry Breaking for Black-Scholes Equations

    Science.gov (United States)

    Yang, Xuan-Liu; Zhang, Shun-Li; Qu, Chang-Zheng

    2007-06-01

    Black-Scholes equation is used to model stock option pricing. In this paper, optimal systems with one to four parameters of Lie point symmetries for Black-Scholes equation and its extension are obtained. Their symmetry breaking interaction associated with the optimal systems is also studied. As a result, symmetry reductions and corresponding solutions for the resulting equations are obtained.

  10. Symmetry Breaking for Black-Scholes Equations

    International Nuclear Information System (INIS)

    Black-Scholes equation is used to model stock option pricing. In this paper, optimal systems with one to four parameters of Lie point symmetries for Black-Scholes equation and its extension are obtained. Their symmetry breaking interaction associated with the optimal systems is also studied. As a result, symmetry reductions and corresponding solutions for the resulting equations are obtained.

  11. Fragmentation in DNA double-strand breaks

    International Nuclear Information System (INIS)

    DNA double strand breaks are important lesions induced by irradiations. Random breakage model or quantification supported by this concept is suitable to analyze DNA double strand break data induced by low LET radiation, but deviation from random breakage model is more evident in high LET radiation data analysis. In this work we develop a new method, statistical fragmentation model, to analyze the fragmentation process of DNA double strand breaks. After charged particles enter the biological cell, they produce ionizations along their tracks, and transfer their energies to the cells and break the cellular DNA strands into fragments. The probable distribution of the fragments is obtained under the condition in which the entropy is maximum. Under the approximation E≅E0 + E1l + E2l2, the distribution functions are obtained as exp(αl + βl2). There are two components, the one proportional to exp(βl2), mainly contributes to the low mass fragment yields, the other component, proportional to exp(αl), decreases slowly as the mass of the fragments increases. Numerical solution of the constraint equations provides parameters α and β. Experimental data, especially when the energy deposition is higher, support the statistical fragmentation model. (authors)

  12. Report of Break Out Group 1

    DEFF Research Database (Denmark)

    Alward, Randy; Carley, Kathleen M.; Madsen, Fredrik Huitfeldt;

    2006-01-01

    To help understand a network and its ability to continue operating when under attack, the break out group discussed issues that need to be considered when presenting network vulnerability information to an analyst, manager or commander in effective support of that person's "observe, orient, decide...

  13. Weak mixing matrix under permutation symmetry breaking

    International Nuclear Information System (INIS)

    The two-Higgs-doublet extension of the standard electroweak model is considered. A permutation symmetry-breaking scheme is proposed and used to calculate the weak mixing matrix up to second order. The CP-violation factor J and the correction to Bjorken's approximation are then given. A special case is considered

  14. Dynamical Symmetry Breaking in RN Quantum Gravity

    Directory of Open Access Journals (Sweden)

    A. T. Kotvytskiy

    2011-01-01

    Full Text Available We show that in the RN gravitation model, there is no dynamical symmetry breaking effect in the formalism of the Schwinger-Dyson equation (in flat background space-time. A general formula for the second variation of the gravitational action is obtained from the quantum corrections hμν (in arbitrary background metrics.

  15. Physical implications of dynamical symmetry breaking

    International Nuclear Information System (INIS)

    Some model-independent physical implications of a class of hypercolorbased theories of dynamical symmetry-breaking are described and discussed. The role which e+e- colliders can play, in distinguishing between such theories and the canonical methodology, is underlined

  16. Physician-patient communication: breaking bad news.

    Science.gov (United States)

    Fields, Scott A; Johnson, W Michael

    2012-01-01

    Physicians often struggle with how to manage the task of breaking bad news with patients. Moreover, the arduous nature of the task can contribute to physician detachment from the patient or an avoidance of breaking the news in a timely manner. A plan of action can only improve physician confidence in breaking bad news, and also make the task more manageable. Over a decade ago, Rabow and McPhee offered a strategy; the ABCDE plan, which provided a patient centered framework from which to deliver troubling news to patients and families. At the heart of this plan was the creation of a safe environment, the demonstration of timely communication skills, and the display of empathy on the physician's part. Careful consideration of the doctor's own reactions to death and dying also played an important role. A close review of the five tenets of this plan indicates the relevance of Rabow and McPhee's strategy today. The patient base in our nation and state continues to be older, on average, and physicians are faced with numerous patients who have terminal illness. A constructive plan with specific ideas for breaking bad news can help physicians effectively navigate this difficult task. PMID:22655433

  17. Density Functional Simulation of a Breaking Nanowire

    DEFF Research Database (Denmark)

    Nakamura, A.; Brandbyge, Mads; Hansen, Lars Bruno;

    1999-01-01

    We study the deformation and breaking of an atomic-sized sodium wire using density functional simulations. The wire deforms through sudden atomic rearrangements and smoother atomic displacements. The conductance of the wire exhibits plateaus at integer values in units of 2e(2)/h corresponding to a...

  18. Achromatic Breaks for Swift GRBs: Any Evidence?

    OpenAIRE

    S. Covino(INAF - Oss. Astronomico di Brera); Malesani, D.; Tagliaferri, G.; Vergani, S.D.; Chincarini, G.; Kann, D. A.; A. Moretti(Fermilab, Batavia, IL, USA); Stella, L.

    2006-01-01

    The availability of multi-wavelength high-quality data of gamma-ray burst afterglows in the Swift era, contrary to the expectations, did not allow us to fully confirm yet one of the most fundamental features of the standard afterglow picture: the presence of an achromatic break in the decaying light curve. We briefly review the most interesting cases identified so far.

  19. The issue of supersymmetry breaking in strings

    International Nuclear Information System (INIS)

    We discuss the central role that supersymmetry plays in string models, both in spacetime and at the level of the string world-sheet. The problems associated with supersymmetry-breaking are reviewed together with some of the attempts to solve them, in the string as well as the field theory approach

  20. Firm break-up and performance

    Czech Academy of Sciences Publication Activity Database

    Kočenda, Evžen; Hanousek, Jan

    2012-01-01

    Roč. 13, č. 2 (2012), s. 121-143. ISSN 1435-6104 R&D Projects: GA ČR GA402/09/1595 Institutional support: PRVOUK-P23 Keywords : break-up of firms * corporate performance * ownership changes Subject RIV: AH - Economics Impact factor: 0.588, year: 2012

  1. Lifshitz-sector mediated SUSY breaking

    International Nuclear Information System (INIS)

    We propose a novel mechanism of SUSY breaking by coupling a Lorentz-invariant supersymmetric matter sector to non-supersymmetric gravitational interactions with Lifshitz scaling. The improved UV properties of Lifshitz propagators moderate the otherwise uncontrollable ultraviolet divergences induced by gravitational loops. This ensures that both the amount of induced Lorentz violation and SUSY breaking in the matter sector are controlled by ΛHL2/MP2, the ratio of the Hořava-Lifshitz cross-over scale ΛHL to the Planck scale MP. This ratio can be kept very small, providing a novel way of explicitly breaking supersymmetry without reintroducing fine-tuning. We illustrate our idea by considering a model of scalar gravity with Hořava-Lifshitz scaling coupled to a supersymmetric Wess-Zumino matter sector, in which we compute the two-loop SUSY breaking corrections to the masses of the light scalars due to the gravitational interactions and the heavy fields

  2. Symmetry breaking and restoration in gauge theories

    International Nuclear Information System (INIS)

    A review is made of the utilization of the Higgs mechanism in spontaneous symmetry breaking. It is shown that such as ideas came from an analogy with the superconductivity phenomenological theory based on a Ginzburg-Landau lagrangean. The symmetry restoration through the temperature influence is studied. (L.C.)

  3. Numerical Simulation of a Seaway with Breaking

    Science.gov (United States)

    Dommermuth, Douglas; O'Shea, Thomas; Brucker, Kyle; Wyatt, Donald

    2012-11-01

    The focus of this presentation is to describe the recent efforts to simulate a fully non-linear seaway with breaking by using a high-order spectral (HOS) solution of the free-surface boundary value problem to drive a three-dimensional Volume of Fluid (VOF) solution. Historically, the two main types of simulations to simulate free-surface flows are the boundary integral equations method (BIEM) and high-order spectral (HOS) methods. BIEM calculations fail at the point at which the surface impacts upon itself, if not sooner, and HOS methods can only simulate a single valued free-surface. Both also employ a single-phase approximation in which the effects of the air on the water are neglected. Due to these limitations they are unable to simulate breaking waves and air entrainment. The Volume of Fluid (VOF) method on the other hand is suitable for modeling breaking waves and air entrainment. However it is computationally intractable to generate a realistic non-linear sea-state. Here, we use the HOS solution to quickly drive, or nudge, the VOF solution into a non-linear state. The computational strategies, mathematical formulation, and numerical implementation will be discussed. The results of the VOF simulation of a seaway with breaking will also be presented, and compared to the single phase, single valued HOS results.

  4. Eye Movement Desensitization and Reprocessing for Adolescent Depression

    OpenAIRE

    Bae, Hwallip; Kim, Daeho; Park, Yong Chon

    2008-01-01

    While cognitive behavior therapy is considered to be the first-line therapy for adolescent depression, there are limited data on whether other psychotherapeutic techniques are also effective in treating adolescents with depression. This report suggests the potential application of eye movement desensitization and reprocessing (EMDR) for treatment of depressive disorder related, not to trauma, but to stressful life events. At present, EMDR has only been empirically validated for only trauma-re...

  5. Short stature in children and adolescence. Causes, diagnosis and treatment.

    OpenAIRE

    Hussimy Marchena Morera; Alina Ester González Hermida; Jorge Luis Irizar Hernández; Greyci Cuervo-Arango Bernia; Inés Martínez Fernández; Alberto Roteta Dorado

    2008-01-01

    Growth is a biological and dynamic process that begins with fecundation and ends at the final stage of adolescence. Its development is complex and different factors intervene in it. Short stature is the most frequent growth disorder in the daily medical practice; furthermore, it is the entity that produces concern and dissent in the patient and his/her relatives. To recognize and to treat early this growth and development altered in our children and adolescence permits us to adopt diagnosis s...

  6. Recovery from adolescent onset anorexia nervosa : a longitudinal study

    OpenAIRE

    Nilsson, Karin

    2007-01-01

    Anorexia Nervosa is a psychiatric illness with peak onset in ages 14-17. Most cases recover within a few years, but the illness can have a fatal outcome or long duration. Multifactor causes of anorexia nervosa include genetics, personality, family, and socio-cultural factors. This study measures mortality, recovery from anorexia nervosa, and psychosocial outcome of patients with adolescent onset anorexia nervosa that were treated in Child and Adolescent Psychiatry in northern Sweden from 1980...

  7. Characteristics and Treatment Programmes of Adolescent Sexual Offenders

    OpenAIRE

    CANKURTARAN ÖNTAŞ, Doç. Dr. Özlem

    2010-01-01

    Modern childhood approach provided that juvenile offenders are treated different form adult. This article is given information about theoritical expalanation, characteristics, treatment programmes of adolescent sexual offenders. There are two explanation about causes of juvenile sexual offenders. One of model is Ryan, Lane, Davis ve Lsaac (1987)’s sexual abuse cycle. This model assert that when adolescent meet negative reflections, He has negative self concept then has negative coping strateg...

  8. Do Adolescents Prefer Electronic Books to Paper Books?

    OpenAIRE

    Margaret K. Merga

    2015-01-01

    While electronic books offer a range of benefits and may be supposed to be more appealing to young people than paper books, this assumption is often treated as fact by educational researchers. Understanding adolescents’ true current preferences is essential, as incorrect assumptions can lead to decisions which restrict adolescent access to their preferred book mode. The belief that adolescents prefer electronic books to paper books has already led to some school libraries being expunged of pa...

  9. Degeneracy Breaking for K2 Microlens Parallaxes

    Science.gov (United States)

    Gould, Andrew; Yee, Jennifer; Carey, Sean

    2015-10-01

    By adding Spitzer observations to microlensing targets being observed from Kepler and Earth, we will create the first interplanetary network of microlensing observatories. This 3-observatory configuration has the unique potential to break the famous 4-fold degeneracy for space-based microlensing parallaxes. This is crucial both for the interpretation of some individual events and to rigorously validate the statistical methods that are used when (as is usually the case) this special 3-observatory configuration is not possible. The Kepler K2 C9 microlensing campaign will monitor about 4 square degrees of the Bulge from 6 Apr to 29 Jun, with the aim of measuring microlens parallaxes. Spitzer can observe this K2 field from 18 Jun to 26 Jul. The 11-day overlap between the two campaigns will allow us to break the 4-fold degeneracy of about 50 microlensing events. Some of these events will be well-covered over the peak from K2, with Spitzer observations of the falling wing providing the necessary information to break the degeneracy in the K2-Earth parallax. Others will be the reverse, with K2 observations of the rising event breaking the degeneracy in Spitzer-Earth parallaxes (i.e., for events peaking during the Spitzer campaign). Breaking this degeneracy leads to a definitive measurement of the magnitude of the microlens parallax vector, which will enable measurements of the masses and distances of the lens systems, including events with planets that contribute to the ~12 needed to make a first measurement of the Galactic distribution of planets, binaries, and many single-lens events, some of which could be black holes, brown dwarfs, or other interesting objects. The distance distribution of the ensemble of lenses can serve as a probe of Galactic structure. All lightcurves will be reduced using our customized software and then made public (for unrestricted use), within two months of the completion of observations (as we did for our 2015 observations).

  10. Effect of physical activities on obese adolescents

    Directory of Open Access Journals (Sweden)

    Sergio Roberto Adriano Prati

    2008-06-01

    Full Text Available The increase in body fat levels associated with the decrease in physical activities in adolescents has been the concern of recent researches because there is a strong correlation between the growing number of early-age obesity cases and the appearance of cardiovascular diseases, diabetes, hypertension, behavior problems and even death when not treated in time. So this study aimed to analyze through a bibliographical investigation some of the factors that cause obesity in adolescents and propose alternative physical activities to help in the treatment and minimize the problem. The analysis showed that programmed, controlled and adequate physical activities, associated with changes in behavior and lifestyle, may revert obesity condition and improve life quality of these adolescents.

  11. Adolescent boys and girls with behavioral disorders in residential homes: A camera-glasses study

    Directory of Open Access Journals (Sweden)

    Alexander Wettstein

    2013-03-01

    Full Text Available Children and adolescents with behavioral disorders are often referred to residential homes. These homes cater and treat socially disadvantaged adolescents with a history of deviant behavior. This study investigated the environment of eight adolescents in these residential homes and four non-aggressive adolescents living with their families. The daily activities were recorded by using camera-glasses attached to the subject. These activities took place in school, leisure time, family and residential homes. Other additional methods were used to investigate the perception and experience of these adolescents. The results of this study indicate that the adolescents in residential homes have a smaller living space in contrast to the non-aggressive adolescents. They also have less close relationships and fewer interactions with their peers. Moreover they have more conflicts and show more often aggressive behavior and they are more often victims of aggression.

  12. Sex differences in anxiety during adolescence : evidence from rodents and humans

    OpenAIRE

    Lynn, Debra Alana

    2012-01-01

    Anxiety disorders commonly emerge during adolescence, and girls are diagnosed with these disorders more frequently than boys. Understanding why anxiety disorders emerge and why non-clinical anxiety symptoms increase during adolescence is important for understanding this sex difference and how to treat adolescent sufferers. Potential mechanisms, such as puberty or cognitive biases, can be investigated both in humans and in rodent models of anxiety. This thesis aimed to characterise sex differe...

  13. The Impact of Protocol Assignment for Older Adolescents with Hodgkin Lymphoma

    OpenAIRE

    Pieters, Richard S.; Wagner, Henry; Baker, Stephen; Morano, Karen; Ulin, Kenneth; Cicchetti, Maria Giulia; Bishop-Jodoin, Maryann; FitzGerald, Thomas J

    2014-01-01

    Background and Purpose: Hodgkin lymphoma (HL) treatment has evolved to reduce or avoid radiotherapy (RT) dose and volume and minimize the potential for late effects. Some older adolescents are treated on adult protocols. The purpose of this study is to examine the protocol assignment of older adolescents and its impact on radiation dose to relevant thoracic structures. Materials and Methods: Cooperative group data were reviewed and 12 adolescents were randomly selected from a pediatric HL ...

  14. Social instability stress differentially affects amygdalar neuron adaptations and memory performance in adolescent and adult rats

    OpenAIRE

    Sheng-Feng Tsai; Chia-Yuan Chang; Lung Yu; Yu-Min Kuo

    2014-01-01

    Adolescence is a time of developmental changes and reorganization in the brain. It has been hypothesized that stress has a greater neurological impact on adolescents than on adults. However, scientific evidence in support of this hypothesis is still limited. We treated adolescent (4-week-old) and adult (8-week-old) rats with social instability stress for five weeks and compared the subsequent structural and functional changes to amygdala neurons. In the stress-free control condition, the a...

  15. Children and adolescents referred for treatment of anxiety disorders: differences in clinical characteristics

    OpenAIRE

    Waite, Polly; Creswell, Catharine

    2014-01-01

    Background Reports of the clinical characteristics of children and adolescents with anxiety disorders are typically based on community populations or from clinical samples with exclusion criterion applied. Little is known about the clinical characteristics of children and adolescents routinely referred for treatment for anxiety disorders. Furthermore, children and adolescents are typically treated as one homogeneous group although they may differ in ways that are clinically meaningful. Method...

  16. The Impact of Perceived Interpersonal Functioning on Treatment for Adolescent Depression: IPT-A versus Treatment as Usual in School-Based Health Clinics

    Science.gov (United States)

    Gunlicks-Stoessel, Meredith; Mufson, Laura; Jekal, Angela; Turner, J. Blake

    2010-01-01

    Objective: Aspects of depressed adolescents' perceived interpersonal functioning were examined as moderators of response to treatment among adolescents treated with interpersonal psychotherapy for depressed adolescents (IPT-A; Mufson, Dorta, Moreau, & Weissman, 2004) or treatment as usual (TAU) in school-based health clinics. Method: Sixty-three…

  17. Influencing Factors of Breaking Capacity of Double-Break Vacuum Circuit Breakers

    Directory of Open Access Journals (Sweden)

    Shengwen Shu

    2013-06-01

    Full Text Available Using a series arrangement of two vacuum interrupters (VIs has been proved to be an effective way of developing higher voltage vacuum circuit breakers (VCBs, which are known as double-break VCBs. The uniform distribution of the transient recovery voltage (TRV across each VI is very critical for the breaking capacity of double-break VCBs. In this paper, the TRV distribution characteristics of double-break VCBs was studied by the synthetic test and the PSCAD/EMTDC simulation based on a vacuum arc interruption model. The results show that the bias of the TRV distribution ratio is caused by the stray capacitance and the imbalanced post arc plasma characteristic in each VI, which is consistent with the theoretical analysis. Moreover, the negative effect of grading capacitors was discussed. The results show that it is advisable to limit the value of grading capacitors to those ranges which can guarantee sufficiently improve the voltage distribution.

  18. Primary prevention of adolescent pregnancy.

    Science.gov (United States)

    Schinke, S P; Blythe, B J; Gilchrist, L D; Burt, G A

    1981-01-01

    Teenage pregnancy is associated with many health, emotional and socioeconomic problems including higher rates of anemia, labor complications, mortality, legal and social struggles and hhigher divorce rates. Professional social workers need strategies to help teenagers avoid early, unwanted pregnancy. This paper offers promising experential and research backing for a primary prevention group work strategy for all adolescents. Social and health programs overlook educational, cognitive anc interpersonal factors biasing youths' ability to comprehend and regulate contraception. Primary prevention to assist adolescents in thinking analytically about their sexual behavior must stress problem solving and decision-making as well as facts about human reproduction and birth control. To implement decisions, youths also need interpersonal communication skills. Small groups are ideal for delivering cognitive-behavioral primary prevention. This approach is based on the premise that youths become pregnant not because of a lack of relevant information, but because they lack cognitive and behavioral skills necessary to use information. Group work involving role-playing helps develop communication skills. Results from 2 field studies describe short-term and longitudinal benefits of the prevention strategy. Professionals can reach significant numbers of youth in this way. By treating sexual issues and the risk of pregnancy as normal in adolescence, social workers can introduce information and pertinent skills to all teenagers. No one is singled out as deviant and the group format enables young people to discuss taboo topics, discovering what the norms are and gradually learning how to deal with peers, family members, techers and others. Adolescents in primary prevention groups gained knowledge, cognitive skills and communication acumen. Improved attitudes toward family planning, increased regular contraception and less unsafe sex resulted from this cognitive-behavioral approach

  19. A longitudinal biosocial study of cortisol and peer influence on the development of adolescent antisocial behavior.

    Science.gov (United States)

    Platje, E; Vermeiren, R R J M; Raine, A; Doreleijers, T A H; Keijsers, L G M T; Branje, S J T; Popma, A; van Lier, P A C; Koot, H M; Meeus, W H J; Jansen, L M C

    2013-11-01

    It is increasingly recognized that in order to understand the complex phenomenon of antisocial behavior, interrelations between biological and social risk factors should be taken into account. In the current study, this biosocial approach was applied to examine the mediating role of deviant peers in longitudinal associations linking the level of hypothalamic-pituitary-adrenal (HPA) axis activity to aggression and rule-breaking. Participants were 425 boys and girls from the general population, who were assessed yearly at ages 15, 16, and 17. As a measure of HPA axis activity, cortisol was assessed at awakening, 30, and 60 min later (the cortisol awakening response, CAR). Participants, as well as their best friend, reported on their own aggressive and rule-breaking behavior, thereby allowing to assess bidirectional influences within friendships. Aggression was only predicted by a decreased cortisol level at awakening, and not by aggressive behavior of their friend. Decreased levels of cortisol at awakening predicted adolescents' rule-breaking, which subsequently predicted increased rule-breaking of their best friend. The latter was only found for adolescents who changed friends, as compared to adolescents with the same friend in every year. Gender differences were not found. These findings suggest that interrelations between biological and social risk factors are different for the development of aggression versus rule-breaking. Furthermore, decreased levels of HPA axis activity may represent a susceptibility to selecting deviant peers. PMID:23927935

  20. Radiation-induced DNA strand breaks and the relationship between strand breaks and fecundity in mosquitofish

    International Nuclear Information System (INIS)

    Mosquitofish (Gambusia affines) were collected from a small pond on the US DOE reservation that is contaminated with 137Cs, 90Sr and other radionuclides. Fish from non-contaminated populations were also collected. DNA was isolated from both the liver and the blood and examined for DNA single- and double-strand breaks by gel electrophoresis. In general, both single- and double-strand DNA breaks were more prevalent in fish from radionuclide-contaminated sites than from uncontaminated sites. In addition, there were more double-strand than single-strand breaks in DNA from contaminated fish, and more strand breaks in blood cell than in liver DNA. Also, fecundity and number of malformed embryos were determined in fish from all sites. It was found that, for fish from the contaminated site, the number of DNA strand breaks was negatively correlated with fecundity, and that females with malformed embryos in their broods had more DNA strand breaks than did females with no malformed embryos. These findings have implications for both ecological risk assessment and evolutionary ecology

  1. Breast fibroadenomas in adolescents: current perspectives

    Directory of Open Access Journals (Sweden)

    Lee M

    2015-09-01

    Full Text Available Michelle Lee, Hooman T SoltanianDepartment of Plastic and Reconstructive Surgery, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, OH, USAAbstract: Fibroadenomas are one of the most common benign tumors of the breast in the adolescent population. They account for 68% of all breast masses and 44%–94% of all biopsied breast lesions. Fibroadenomas can range from asymptomatic masses to painful and rapidly growing tumors that can cause significant esthetic distortions of the breast. Given the prevalence of fibroadenomas in the adolescent population and the psychosocial morbidity of finding a mass in the adolescent breast, it is imperative for physicians treating adolescent patients to be familiar and up to date with this disease process. The goal of this article is to provide a brief review of the classification, etiology, symptoms, initial work-up, and update on the management of breast fibroadenomas in the adolescent population.Keywords: breast mass, benign breast neoplasm, breast growth, breast development, breast asymmetry

  2. Chiral symmetry breaking in d=3 NJL model in external gravitational and magnetic fields

    CERN Document Server

    Gitman, D M

    1996-01-01

    The phase structure of d=3 Nambu-Jona-Lasinio model in curved spacetime with magnetic field is investigated in the leading order of the 1/N-expansion and in linear curvature approximation (an external magnetic field is treated exactly). The possibility of the chiral symmetry breaking under the combined action of the external gravitational and magnetic fields is shown explicitly. At some circumstances the chiral symmetry may be restored due to the compensation of the magnetic field by the gravitational field.

  3. Chiral symmetry breaking in d=3 NJL model in external gravitational and magnetic fields

    OpenAIRE

    Gitman, D. M.; Odintsov, S. D.; Shil'nov, Yu. I.

    1996-01-01

    The phase structure of $d=3$ Nambu-Jona-Lasinio model in curved spacetime with magnetic field is investigated in the leading order of the $1/N$-expansion and in linear curvature approximation (an external magnetic field is treated exactly). The possibility of the chiral symmetry breaking under the combined action of the external gravitational and magnetic fields is shown explicitly. At some circumstances the chiral symmetry may be restored due to the compensation of the magnetic field by the ...

  4. Integral measurement of break-up excitation function using a multiple silicon telescope

    International Nuclear Information System (INIS)

    A simple method is proposed for measuring the inclusive break-up excitation function which the experimental device, consisting of a set of successive silicon detectors, serves the double purpose of decreasing the incident beam energy and of detecting and identifying the reaction products. Monte Carlo simulations revealed the merits and the limitations of the method. Finally, experimental data for tritons are treated in order to obtain relevant physical informations (authors). 9 refs., 9 figs

  5. Interventions for treating obesity in children.

    Science.gov (United States)

    De Miguel-Etayo, Pilar; Bueno, Gloria; Garagorri, Jesús M; Moreno, Luis A

    2013-01-01

    Childhood obesity remains an important public health concern and prevention programmes should be the priority in order to decrease the prevalence of obesity. The aim of this review is to summarize the most effective types of intervention for treating obesity in children and adolescents. A number of identified strategies used to treat childhood obesity range from lifestyle approaches, pharmacotherapy to surgical intervention. Dietary treatment of obese children and adolescents should aim to ensure adequate growth and development by reducing excessive fat mass accumulation, avoiding loss of lean body mass, improving well-being and self-esteem, and preventing cyclical weight regain. Management protocols involve behaviour modifications, family support, and lifestyle changes which are difficult to put into practice and may require multidisciplinary professional teams. The cornerstone of weight loss programmes is to achieve a negative energy balance. There is evidence that dietary interventions are more effective in achieving weight loss when combined with other strategies, such as increasing physical activity levels and/or psychological interventions to promote behavioural changes. Psychological interventions have been employed in an effort to achieve long-term maintenance of behavioural change. Childhood obesity treatments should involve a combination of lifestyle changes including strategies to reduce energy intake, increase physical activity, reduce sedentary activities, facilitate family involvement and change behaviours associated with eating and physical activity. However, drug therapy in obese children must not be used as isolated treatment but as complementary to the traditional treatments of diet, physical activity and lifestyle changes. Besides, surgical procedures have been used to treat severe morbid obesity in children and adolescents when more conservative treatments have proven to be inadequate. PMID:24029793

  6. Participants' Experiences of an Early Cognitive Behavioral Intervention for Adolescents with Symptoms of Depression

    Science.gov (United States)

    Bru, Lene; Solholm, Roar; Idsoe, Thormod

    2013-01-01

    Cognitive-behavioral therapy (CBT) has been documented to be effective in treating depression in adolescence, but there is great variability in the clinical outcome of CBT trials. This may in part be due to variations in the content of, and emphasis on different CBT components. Moreover, little is known about adolescents' subjective experiences of…

  7. Pilot Study: Fluvoxamine Treatment for Depression and Anxiety Disorders in Children and Adolescents with Cancer

    Science.gov (United States)

    Gothelf, Doron; Rubinstein, Maly; Shemesh, Eyal; Miller, Orit; Farbstein, Ilana; Klein, Anat; Weizman, Abraham; Apter, Alan; Yaniv, Isaac

    2005-01-01

    Objective: To evaluate the safety, tolerability, and benefit of fluvoxamine for the treatment of major depressive disorder or anxiety disorders in children and adolescents with cancer. Method: The study was conducted from 2001 to 2004 at a pediatric hematology-oncology center. Fifteen children and adolescents with cancer were treated with…

  8. Impact of antipsychotic medication on physical activity and physical fitness in adolescents: An exploratory study.

    Science.gov (United States)

    Vancampfort, Davy; Probst, Michel; Daenen, Anne; Damme, Tine Van; De Hert, Marc; Rosenbaum, Simon; Bruyninckx, David

    2016-08-30

    Antipsychotics are used increasingly in adolescents for a range of psychiatric disorders. The aim of the current study was to investigate whether physical activity levels and physical fitness of adolescent inpatients treated with antipsychotic medication, differs from either (i) antipsychotic naïve adolescents with mental health problems and, (ii) healthy controls. All participants completed the Physical Activity Questionnaire for Adolescents, the Positive-and-Negative-Affect-Schedule and performed the Eurofit test battery. Adolescents with mental health problems (irrespective of antipsychotic medication) were significantly (Prunning speed and cardiovascular endurance compared to healthy controls (n=15, 8♂, 15.9±1.3 years). Adolescents treated with antipsychotic medication (n=15, 8♂, 15.5±1.3 years) were less physically active and had an impaired whole body balance compared with antipsychotic naïve adolescents (n=15, 8♂, 15.7±1.4 years). Given the overwhelming deleterious impact of physical inactivity and low physical fitness on physical and mental health outcomes, interventions specifically targeting physical activity and physical fitness among adolescents experiencing mental illness, both treated with, and not treated with antipsychotic medication are warranted as a priority. Antipsychotic medication should be considered as a risk factor for physical inactivity and poor physical fitness. PMID:27288738

  9. Crack and Cocaine Use among Adolescents in Psychiatric Treatment: Associations with HIV Risk

    Science.gov (United States)

    Tolou-Shams, Marina; Feldstein Ewing, Sarah W. Tarantino, Nicholas; Brown, Larry K.

    2010-01-01

    Crack and cocaine use among adults has been associated with co-occurring psychiatric disorders as well as other drug use and unprotected sex. However, this issue is relatively unstudied in adolescents. This study collected data from 282 adolescents (mean age = 14.9 years) treated in intensive psychiatric treatment settings to understand the…

  10. Webcam Delivery of the Camperdown Program for Adolescents Who Stutter: A Phase II Trial

    Science.gov (United States)

    Carey, Brenda; O'Brian, Sue; Lowe, Robyn; Onslow, Mark

    2014-01-01

    Purpose: This Phase II clinical trial examined stuttering adolescents' responsiveness to the Webcam-delivered Camperdown Program. Method: Sixteen adolescents were treated by Webcam with no clinic attendance. Primary outcome was percentage of syllables stuttered (%SS). Secondary outcomes were number of sessions, weeks and hours to maintenance,…

  11. Webcam Delivery of the Camperdown Program for Adolescents Who Stutter: A Phase I Trial

    Science.gov (United States)

    Carey, Brenda; O'Brian, Sue; Onslow, Mark; Packman, Ann; Menzies, Ross

    2012-01-01

    Purpose: This Phase I clinical trial explored the viability of webcam Internet delivery of the Camperdown Program for adolescents who stutter. Method and Procedure: Participants were 3 adolescents ages 13, 15, and 16 years, with moderate-severe stuttering. Each was treated with the Camperdown Program delivered by webcam with no clinic attendance.…

  12. Surgery for the treatment of obesity in children and adolescents (Review)

    NARCIS (Netherlands)

    Ells, Louisa J.; Mead, Emma; Atkinson, Greg; Corpeleijn, Eva; Roberts, Katharine; Viner, Russell; Baur, Louise; Metzendorf, Maria-Inti; Richter, Bernd

    2015-01-01

    Background Child and adolescent overweight and obesity have increased globally, and are associated with significant short and long term health consequences. Objectives To assess the effects of surgical interventions for treating obesity in childhood and adolescence. Search methods We searched the Co

  13. Alliance and Outcome in Cognitive-Behavioral Therapy for Adolescent Depression

    Science.gov (United States)

    Shirk, Stephen R.; Gudmundsen, Gretchen; Kaplinski, Heather Crisp; McMakin, Dana L.

    2008-01-01

    This study examined predictive relations between therapeutic alliance and treatment outcomes in manual-guided, cognitive-behavioral therapy for adolescent depression. Fifty-four adolescents met criteria for a depressive disorder and were treated in school-based clinics. Alliance was measured after the third session from both therapist and…

  14. Adolescents' Thoughts about Abstinence Curb the Return of Marijuana Use during and after Treatment

    Science.gov (United States)

    King, Kevin M.; Chung, Tammy; Maisto, Stephen A.

    2009-01-01

    Despite evidence showing that readiness to change substance use predicts reductions in substance use among treated adolescents, there is little research on changes in thoughts about abstinence and marijuana use during and after treatment. The current study tested whether time-varying changes in adolescents' motivation to abstain and perceived…

  15. A Fourth Chiral Generation And Susy Breaking

    CERN Document Server

    Wingerter, Akin

    2011-01-01

    We revisit four generations within the context of supersymmetry. We compute the perturbativity limits for the fourth generation Yukawa couplings and show that if the masses of the fourth generation lie within reasonable limits of their present experimental lower bounds, it is possible to have perturbativity only up to scales around 1000 TeV, i.e. the current experimental bounds and perturbative unification are mutually exclusive. Such low scales are ideally suited to incorporate gauge mediated supersymmetry breaking, where the mediation scale can be as low as 10-20 TeV. The minimal messenger model, however, is highly constrained. Lack of electroweak symmetry breaking rules out a large part of the parameter space, and in the remaining part, the fourth generation stau is tachyonic.

  16. Four Generations: SUSY and SUSY Breaking

    CERN Document Server

    Godbole, Rohini M; Wingerter, Akin

    2009-01-01

    We revisit four generations within the context of supersymmetry. We compute the perturbativity limits for the fourth generation Yukawa couplings and show that if the masses of the fourth generation lie within reasonable limits of their present experimental lower bounds, it is possible to have perturbativity only up to scales around 1000 TeV. Such low scales are ideally suited to incorporate gauge mediated supersymmetry breaking, where the mediation scale can be as low as 10-20 TeV. The minimal messenger model, however, is highly constrained. While lack of electroweak symmetry breaking rules out a large part of the parameter space, a small region exists, where the fourth generation stau is tachyonic. General gauge mediation with its broader set of boundary conditions is better suited to accommodate the fourth generation.

  17. Fractional Branes and Dynamical Supersymmetry Breaking

    CERN Document Server

    Franco, S; Saad, F; Uranga, Angel M; Franco, Sebastian; Hanany, Amihay; Saad, Fouad; Uranga, Angel M.

    2006-01-01

    We study the dynamics of fractional branes at toric singularities, including cones over del Pezzo surfaces and the recently constructed Y^{p,q} theories. We find that generically the field theories on such fractional branes show dynamical supersymmetry breaking, due to the appearance of non-perturbative superpotentials. In special cases, one recovers the known cases of supersymmetric infrared behaviors, associated to SYM confinement (mapped to complex deformations of the dual geometries, in the gauge/string correspondence sense) or N=2 fractional branes. In the supersymmetry breaking cases, when the dynamics of closed string moduli at the singularity is included, the theories show a runaway behavior (involving moduli such as FI terms or equivalently dibaryonic operators), rather than stable non-supersymmetric minima. We comment on the implications of this gauge theory behavior for the infrared smoothing of the dual warped throat solutions with 3-form fluxes, describing duality cascades ending in such field th...

  18. Symmetry breaking in non conservative systems

    CERN Document Server

    Martínez-Pérez, N E

    2016-01-01

    We apply Noether's theorem to show how the invariances of conservative systems are broken for nonconservative systems, in the variational formulation of Galley. This formulation considers a conservative action, extended by the inclusion of a time reversed sector and a nonconservative generalized potential. We assume that this potential is invariant under the symmetries of the initial conservative system. The breaking occurs because the time reversed sector requires inverse symmetry transformations, under which the nonconservative potential is not invariant. The resulting violation of the conservation laws is consistent with the equations of motion. We generalize this formulation for fermionic and sypersymmetric systems. In the case of a supersymmetric oscillator, the effect of damping is that the bosonic and fermionic components become different frequencies. Considering that initially the nonconservative action is invariant under supersymmetry, and that the breaking is associated to an instability, this resul...

  19. The Radiative Z2 Breaking Twin Higgs

    CERN Document Server

    Yu, Jiang-Hao

    2016-01-01

    In twin Higgs model, the Higgs boson mass is protected by a $Z_2$ symmetry. The $Z_2$ symmetry needs to be broken either explicitly or spontaneously to obtain misalignment between electroweak and new physics vacua. We propose a novel $Z_2$ breaking mechanism, in which the $Z_2$ is spontaneously broken by radiative corrections to the Higgs potential. Two twin Higgses with different vacua are needed, and vacuum misalignment is realized by opposite but comparable contributions from gauge and Yukawa interactions to the potential. Due to fully radiative symmetry breaking, the Higgs sector is completely determined by twin Higgs vacuum, Yukawa and gauge couplings. There are eight pseudo-Goldstone bosons: the Higgs boson, inert doublet Higgs, and three twin scalars. We show the 125 GeV Higgs mass and constraints from Higgs coupling measurements could be satisfied.

  20. Mechanics of breaking coal by water jet

    Energy Technology Data Exchange (ETDEWEB)

    Chang, Z.; Xi, B.; Zhao, Y.; Zhao, L. [Taiyuan University of Technology, Taiyuan (China)

    2008-09-15

    It is presumed that the elastic modulus and compressive strength of inhomogeneous rock conform to the Weibull distribution. The methods of breaking inhomogeneous rock by water jet and the threshold pressure of the water jet were deduced using percolation theory. Continuous drilling in the inhomogeneous coal by water jet was numerically simulated by the finite element method and an experiment of breaking coal by water jet was carried out. The study indicated that under the pressure of water jets, the low strength cells in inhomogeneous rock are first destroyed and a crack is created. The effect of a water wedge occurring by the water jet entering the crack space produces a tensile stress concentration at the tip of a crack, so cracks expand rapidly and converge gradually. Eventually the rock is fragmented and a cracked pit forms. The length of a crack in coal caused by a water jet at 60 MPa is over 0.5 m. 8 refs., 6 figs.

  1. Phenomenological implications of low energy supersymmetry breaking

    International Nuclear Information System (INIS)

    The experimental signatures for low energy supersymmetry breaking are presented. The lightest standard model superpartner is unstable and decays to its partner plus a Goldstino, G. For a supersymmetry breaking scale below a few 1000 TeV this decay can take place within a detector, leading to very distinctive signatures. If a neutralino is the lightest standard model superpartner it decays by χ01→γ + G, and if kinematically accessible by χ01 → (Z0, h0, H0, A0) + G. These decays can give rise to displaced vertices. Alternately, if a slepton is the lightest standard model superpartner it decays by l→l + G. This can be seen as a greater than minimum ionizing charged particle track, possibly with a kink to a minimum ionizing track. (orig.)

  2. Electroweak symmetry breaking: Higgs/whatever

    International Nuclear Information System (INIS)

    In the first of these two lectures the Higgs mechanism is reviewed in its most general form, which does not necessarily require the existence of Higgs bosons. The general consequences of the hypothesis that electroweak symmetry breaking is due to the Higgs mechanism are deduced just from gauge invariance and unitarity. In the second lecture the general properties are illustrated with three specific models: the Weinberg-Salam model, its minimal supersymmetric extension, and technicolor. The second lecture concludes with a discussion of the experiment signals for strong WW scattering, whose presence or absence will allow us to determine whether the symmetry breaking sector lies above or below 1 TeV. 57 refs

  3. Rotation Breaking Induced by ELMs on EAST

    DEFF Research Database (Denmark)

    Xiong, H.; Xu, G.; Sun, Y.;

    Spontaneous rotation has been observed in LHCD H-mode plasmas with type III ELMs (edge localized modes) on EAST, and it revealed that type III ELMs can induce the loss of both core and edge toroidal rotation. Here we work on the breaking mechanism during the ELMs. Several large tokamaks have...... of magnetic surface, thus generate NTV (neoclassical toroidal viscosity) torque that affects toroidal rotation. We adopt 1cm maximum edge magnetic surface displacement from experimental observation, and our calculation shows that the edge torque is about 0.35 N/m2, and the core very small. The...... expected angular momentum density change is about 3.8 N/m2, nearly 10 times larger than the calculation. Previous work on EAST has suggested that there is a mechanism at the edge that breaks the rotation, while the core rotation change is mostly likely related with momentum transport to the edge. In other...

  4. Analysis of chiral symmetry breaking mechanism

    International Nuclear Information System (INIS)

    The renormalization group invariant quark condensate μ is determinate both from the consistent equation for quark condensate in the chiral limit and from the Schwinger-Dyson (SD) equation improved by the intermediate range QCD force singular like δ (q) which is associated with the gluon condensate. The solutions of μ in these two equations are consistent. We also obtain the critical strong coupling constant αc above which chiral symmetry breaks in two approaches. The nonperturbative kernel of the SD equation makes αc smaller and μ bigger. An intuitive picture of the condensation above αc is discussed. In addition, with the help of the Slavnov-Taylor-Ward (STW) identity we derive the equations for the nonperturbative quark propagator from SD equation in the presence of the intermediate-range force is also responsible for dynamical chiral symmetry breaking. (author)

  5. Boost Breaking in the EFT of Inflation

    CERN Document Server

    Delacretaz, Luca V; Senatore, Leonardo

    2015-01-01

    If time-translations are spontaneously broken, so are boosts. This symmetry breaking pattern can be non-linearly realized by either just the Goldstone boson of time translations, or by four Goldstone bosons associated with time translations and boosts. In this paper we extend the Effective Field Theory of Multifield Inflation to consider the case in which the additional Goldstone bosons associated with boosts are light and coupled to the Goldstone boson of time translations. The symmetry breaking pattern forces a coupling to curvature so that the mass of the additional Goldstone bosons is predicted to be equal to $\\sqrt{2}H$ in the vast majority of the parameter space where they are light. This pattern therefore offers a natural way of generating self-interacting particles with Hubble mass during inflation. After constructing the general effective Lagrangian, we study how these particles mix and interact with the curvature fluctuations, generating potentially detectable non-Gaussian signals.

  6. Nuclear break-up of 11Be

    CERN Document Server

    Lima, V; Lacroix, D; Blumenfeld, Y; Bourgeois, C; Chabot, M; Chomaz, Ph; Désesquelles, P; Duflot, V; Duprat, J; Fallot, M; Frascaria, N; Grévy, S; Guillemaud-Müller, D; Roussel-Chomaz, P; Savajols, H; Sorlin, O

    2007-01-01

    The break-up of 11Be was studied at 41AMeV using a secondary beam of 11Be from the GANIL facility on a 48Ti target by measuring correlations between the 10Be core, the emitted neutrons and gamma rays. The nuclear break-up leading to the emission of a neutron at large angle in the laboratory frame is identified with the towing mode through its characteristic n-fragment correlation. The experimental spectra are compared with a model where the time dependent Schrodinger equation (TDSE) is solved for the neutron initially in the 11 Be. A good agreement is found between experiment and theory for the shapes of neutron experimental energies and angular distributions. The spectroscopic factor of the 2s orbital is tentatively extracted to be 0.46+-0.15. The neutron emission from the 1p and 1d orbitals is also studied.

  7. Isospin breaking in octet baryon mass splittings

    Energy Technology Data Exchange (ETDEWEB)

    Horsley, R. [Edinburgh Univ. (United Kingdom). School of Physics and Astronomy; Najjar, J. [Regensburg Univ. (Germany). Institut fuer Theoretische Physik; Nakamura, Y. [RIKEN Advanced Institute for Computational Science, Kobe, Hyogo (Japan); Pleiter, D. [Forschungszentrum Juelich (Germany). Juelich Supercomputer Centre; Rakow, P.E.L. [Liverpool Univ. (United Kingdom). Theoretical Physics Division; Schierholz, G. [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Zanotti, J.M. [Adelaide Univ., SA (Australia). CSSM, School of Chemistry and Physics

    2012-06-15

    Using an SU(3) flavour symmetry breaking expansion in the quark mass, we determine the QCD component of the nucleon, Sigma and Xi mass splittings of the baryon octet due to up-down (and strange) quark mass differences in terms of the kaon mass splitting. Provided the average quark mass is kept constant, the expansion coefficients in our procedure can be determined from computationally cheaper simulations with mass degenerate sea quarks and partially quenched valence quarks. Both the linear and quadratic terms in the SU(3) flavour symmetry breaking expansion are considered; it is found that the quadratic terms only change the result by a few percent, indicating that the expansion is highly convergent.

  8. Isospin breaking in octet baryon mass splittings

    International Nuclear Information System (INIS)

    Using an SU(3) flavour symmetry breaking expansion in the quark mass, we determine the QCD component of the nucleon, Sigma and Xi mass splittings of the baryon octet due to up-down (and strange) quark mass differences in terms of the kaon mass splitting. Provided the average quark mass is kept constant, the expansion coefficients in our procedure can be determined from computationally cheaper simulations with mass degenerate sea quarks and partially quenched valence quarks. Both the linear and quadratic terms in the SU(3) flavour symmetry breaking expansion are considered; it is found that the quadratic terms only change the result by a few percent, indicating that the expansion is highly convergent.

  9. Symmetry Breaking in Neuroevolution: A Technical Report

    CERN Document Server

    Urfalioglu, Onay

    2011-01-01

    Artificial Neural Networks (ANN) comprise important symmetry properties, which can influence the performance of Monte Carlo methods in Neuroevolution. The problem of the symmetries is also known as the competing conventions problem or simply as the permutation problem. In the literature, symmetries are mainly addressed in Genetic Algoritm based approaches. However, investigations in this direction based on other Evolutionary Algorithms (EA) are rare or missing. Furthermore, there are different and contradictionary reports on the efficacy of symmetry breaking. By using a novel viewpoint, we offer a possible explanation for this issue. As a result, we show that a strategy which is invariant to the global optimum can only be successfull on certain problems, whereas it must fail to improve the global convergence on others. We introduce the \\emph{Minimum Global Optimum Proximity} principle as a generalized and adaptive strategy to symmetry breaking, which depends on the location of the global optimum. We apply the...

  10. Testing Chiral Symmetry Breaking at DAPHNE

    OpenAIRE

    M. R. Pennington

    1996-01-01

    The spontaneous breakdown of the chiral symmetry of the QCD Lagrangian ensures that $\\pi\\pi$ interactions are weak at low energies. How weak depends on the nature of explicit symmetry breaking. Measurements of $K_{e4}$ decays at DA$\\Phi$NE will provide a unique insight into this mechanism and test whether the $q{\\overline q}$--condensate is large or small.

  11. Music and Video Gaming during Breaks

    OpenAIRE

    Liu, Shuyan; Schad, Daniel J.; Kuschpel, Maxim S.; Michael A Rapp; Heinz, Andreas

    2016-01-01

    Different systems for habitual versus goal-directed control are thought to underlie human decision-making. Working memory is known to shape these decision-making systems and their interplay, and is known to support goal-directed decision making even under stress. Here, we investigated if and how decision systems are differentially influenced by breaks filled with diverse everyday life activities known to modulate working memory performance. We used a within-subject design where young adult...

  12. Supersymmetry breaking made easy, viable, and generic

    CERN Document Server

    Murayama, Hitoshi

    2007-01-01

    The kind of supersymmetry that can be discovered at the LHC must be very much flavor-blind, which used to require very special intelligently designed models of supersymmetry breaking. This led to the pessimism for some in the community that it is not likely for the LHC to discover supersymmetry. I point out that this is not so, because a garden-variety supersymmetric theories actually can do this job.

  13. The Experimental Investigation of Supersymmetry Breaking

    OpenAIRE

    Peskin, Michael E.

    1996-01-01

    If Nature is supersymmetric at the weak interaction scale, what can we hope to learn from experiments on supersymmetric particles? The most mysterious aspect of phenomenological supersymmetry is the mechanism of spontaneous supersymmetry breaking. This mechanism ties the observable pattern of supersymmetric particle masses to aspects of the underlying unified theory at very small distance scales. In this article, I will discuss a systematic experimental program to determine the mechanism of s...

  14. Numerical simulation of 3D breaking waves

    Science.gov (United States)

    Fraunie, Philippe; Golay, Frederic

    2015-04-01

    Numerical methods dealing with two phase flows basically can be classified in two ways : the "interface tracking" methods when the two phases are resolved separately including boundary conditions fixed at the interface and the "interface capturing" methods when a single flow is considered with variable density. Physical and numerical properties of the two approaches are discussed, based on some numerical experiments performed concerning 3D breaking waves. Acknowledgements : This research was supported by the Modtercom program of Region PACA.

  15. Dynamical symmetry breaking in quantum field theories

    CERN Document Server

    Miransky, Vladimir A

    1993-01-01

    The phenomenon of dynamical symmetry breaking (DSB) in quantum field theory is discussed in a detailed and comprehensive way. The deep connection between this phenomenon in condensed matter physics and particle physics is emphasized. The realizations of DSB in such realistic theories as quantum chromodynamics and electroweak theory are considered. Issues intimately connected with DSB such as critical phenomenona and effective lagrangian approach are also discussed.

  16. Spontaneous symmetry breaking of SU(n)

    International Nuclear Information System (INIS)

    The spontaneous symmetry breaking pattern for the gauge group SU(n) is found by studying the absolute minimum of the Higgs potential, chosen as a polynomial of degree 4 of one adjoint and one fundamental representation. SU(n) may be broken into SU(n - 1) or SU(h) x SU(n - 1 - h) x U(1) (h = 1,...n - 2), depending on the values of the parameters, but without any assumption on their smallness. (orig.)

  17. Wave breaking in tapered holey fibers

    Institute of Scientific and Technical Information of China (English)

    Shuguang Li; Lei Zhang; Bo Fu; Yi Zheng; Ying Han; Xingtao Zhao

    2011-01-01

    We numerically study the propagation of 1-ps laser pulse in three tapered holey fibers (THFs). The curvature indices of the concave, linear, and convex tapers are 2.0, 1.0, and 0.5, respectively. The central wavelength, located in the normal dispersion regime, is 800 nm. The nonlinear coefficient of the THFs increases from the initial 0.095 m-1· W-1 to the final 0.349 m-l·W-1. Wave breaking accompanied by oscillatory structures occurs near pulse edges, and sidelobes appear in the pulse spectrum. With the increase in propagation distance z, the pulse shape becomes broader and the pulse spectrum flattens. A concave THF is advantageous to the generation of wave breaking and enables easier achievement of super fiat spectra at short lengths.%@@ We numerically study the propagation of 1-ps laser pulse in three tapered holey fibers (THFs).The curvature indices of the concave, linear, and convex tapers are 2.0, 1.0, and 0.5, respectively.The central wavelength, located in the normal dispersion regime, is 800 nm.The nonlinear coefficient of the THFs increases from the initial 0.095 m-1.W-1 to the final 0.349 m-1.W-1.Wave breaking accompanied by oscillatory structures occurs near pulse edges, and sidelobes appear in the pulse spectrum.With the increase in propagation distance z, the pulse shape becomes broader and the pulse spectrum flattens.A concave THF is advantageous to the generation of wave breaking and enables easier achievement of super flat spectra at short lengths.

  18. Soft branes in supersymmetry-breaking backgrounds

    OpenAIRE

    McGuirk, Paul; Shiu, Gary; Ye, Fang

    2012-01-01

    We revisit the analysis of effective field theories resulting from non-supersymmetric perturbations to supersymmetric flux compactifications of the type-IIB superstring with an eye towards those resulting from the backreaction of a small number of anti-D3-branes. Independently of the background, we show that the low-energy Lagrangian describing the fluctuations of a stack of probe D3-branes exhibits soft supersymmetry breaking, despite perturbations to marginal operators that were not fully c...

  19. Electroweak Symmetry Breaking Beyond the Standard Model

    OpenAIRE

    Bhattacharyya, Gautam

    2012-01-01

    In this talk, I shall address two key issues related to electroweak symmetry breaking. First, how fine-tuned different models are that trigger this phenomenon? Second, even if a light Higgs boson exists, does it have to be necessarily elementary? After a brief introduction, I shall first review the fine-tuning aspects of the MSSM, NMSSM, generalized NMSSM and GMSB scenarios. I shall then compare and contrast the little Higgs, composite Higgs and the Higgsless models. Finally, I shall summariz...

  20. Induced Higgs couplings and spontaneous symmetry breaking

    International Nuclear Information System (INIS)

    It is shown that spontaneous symmetry breaking can arise in a non-Abelian gauge theory free of quartic scalar couplings only if fermions are present in the theory. A sufficiency condition is developed for positivity of the induced PHI4-potential as PHI→infinity. The same condition guarantees the existence of asymptotically free positive-eigenvalue solutions to the renormalization group equations for running coupling constants. Correspondence is established between ''eigenvalue'' and induced-potential approaches toward total asymptotic freedom. (author)

  1. Symmetry Breaking in Topological Quantum Gravity

    Science.gov (United States)

    Mielke, Eckehard W.

    2015-01-01

    A SL(5, R) gauge-invariant topological field theory of gravity and possible gauge unifications are considered in four-dimensions. The problem of quantization is evaluated in the asymptotic safety scenario. `Minimal' BF type models for the high energy limit are physically not quite realistic, a tiny symmetry breaking is needed to recover standard Einsteinian gravity for the oscopic metrical background with induced cosmological constant.

  2. Center vortices, confinement and chiral symmetry breaking

    International Nuclear Information System (INIS)

    The center vortex model, proposed as an explanation of confinement in non-abelian gauge theories is introduced. Some checks of the confinement properties of center vortices in SU(2) lattice gauge theory with improved Luescher-Weisz gauge action are presented. Phenomena related to chiral symmetry, such as topological charge and spontaneous chiral symmetry breaking (SCSB) are studied within the vortex model. In particular the influence of center vortices on the low-lying spectrum of the Dirac operator is analyzed. (author)

  3. How does DNA break during chromosomal translocations?

    OpenAIRE

    Nambiar, Mridula; Raghavan, Sathees C.

    2011-01-01

    Chromosomal translocations are one of the most common types of genetic rearrangements and are molecular signatures for many types of cancers. They are considered as primary causes for cancers, especially lymphoma and leukemia. Although many translocations have been reported in the last four decades, the mechanism by which chromosomes break during a translocation remains largely unknown. In this review, we summarize recent advances made in understanding the molecular mechanism of chromosomal t...

  4. Flavour Violation in Anomaly Mediated Supersymmetry Breaking

    OpenAIRE

    Allanach, B. C.; Hiller, G; Jones, D. R. T.; Slavich, P.(LPTHE, UPMC Univ. Paris 06, Sorbonne Universités, 4 Place Jussieu, 75252, Paris, France)

    2009-01-01

    32 pages, 8 figures International audience We study squark flavour violation in the anomaly mediated supersymmetry broken (AMSB) minimal supersymmetric standard model. Analytical expressions for the three-generational squark mass matrices are derived. We show that the anomaly-induced soft breaking terms have a decreasing amount of squark flavour violation when running from the GUT to the weak scale. Taking into account inter-generational squark mixing, we work out non-trivial constraint...

  5. Breaking of Nanotube Symmetry by Substrate Polarization

    OpenAIRE

    Petrov, Alexey G.; Rotkin, Slava V.

    2003-01-01

    Substrate and nanotube polarization are shown to change qualitatively a nanotube bandstructure. The effect is studied in a linear approximation in an external potential which causes the changes. A work function difference between the nanotube and gold surface is estimated to be large enough to break the band symmetry and lift a degeneracy of a lowest but one subband of a metallic nanotube. This subband splitting for [10,10] nanotube is about 50 meV in absence of other external potential.

  6. Breaking democracy with non renormalizable mass terms

    CERN Document Server

    Silva-Marcos, Joaquim I

    2001-01-01

    The exact democratic structure for the quark mass matrix, resulting from the action of the family symmetry group $A_{3L}\\times A_{3R}$, is broken by the vacuum expectation values of heavy singlet fields appearing in non renormalizable dimension 6 operators. Within this specific context of breaking of the family symmetry we formulate a very simple ansatz which leads to correct quark masses and mixings.

  7. Piecewise-smooth circle homeomorphisms with several break points

    International Nuclear Information System (INIS)

    We prove that the invariant probability measure of an ergodic piecewise-smooth circle homeomorphism with several break points and the product of the jumps at break points non-trivial is singular with respect to Lebesgue measure.

  8. The Beam Break-Up Numerical Simulator

    Energy Technology Data Exchange (ETDEWEB)

    Travish, G.A.

    1989-11-01

    Beam Break-Up (BBU) is a severe constraint in accelerator design, limiting beam current and quality. The control of BBU has become the focus of much research in the design of the next generation collider, recirculating and linear induction accelerators and advanced accelerators. Determining the effect on BBU of modifications to cavities, the focusing elements or the beam is frequently beyond the ability of current analytic models. A computer code was written to address this problem. The Beam Break-Up Numerical Simulator (BBUNS) was designed to numerically solve for beam break-up (BBU) due to an arbitrary transverse wakefield. BBUNS was developed to be as user friendly as possible on the Cray computer series. The user is able to control all aspects of input and output by using a single command file. In addition, the wakefield is specified by the user and read in as a table. The program can model energy variations along and within the beam, focusing magnetic field profiles can be specified, and the graphical output can be tailored. In this note we discuss BBUNS, its structure and application. Included are detailed instructions, examples and a sample session of BBUNS. This program is available for distribution. 50 refs., 18 figs., 5 tabs.

  9. Enhanced breaking of heavy quark spin symmetry

    International Nuclear Information System (INIS)

    Heavy quark spin symmetry is useful to make predictions on ratios of decay or production rates of systems involving heavy quarks. The breaking of spin symmetry is generally of the order of O(ΛQCD/mQ), with ΛQCD the scale of QCD and mQ the heavy quark mass. In this paper, we will show that a small S- and D-wave mixing in the wave function of the heavy quarkonium could induce a large breaking in the ratios of partial decay widths. As an example, we consider the decays of the ϒ(10860) into the χbJω(J=0,1,2), which were recently measured by the Belle Collaboration. These decays exhibit a huge breaking of the spin symmetry relation were the ϒ(10860) a pure 5S bottomonium state. We propose that this could be a consequence of a mixing of the S-wave and D-wave components in the ϒ(10860). Prediction on the ratio Γ(ϒ(10860)→χb0ω)/Γ(ϒ(10860)→χb2ω) is presented assuming that the decay of the D-wave component is dominated by the coupled-channel effects

  10. Kinematic dynamo, supersymmetry breaking, and chaos

    Science.gov (United States)

    Ovchinnikov, Igor V.; Enßlin, Torsten A.

    2016-04-01

    The kinematic dynamo (KD) describes the growth of magnetic fields generated by the flow of a conducting medium in the limit of vanishing backaction of the fields onto the flow. The KD is therefore an important model system for understanding astrophysical magnetism. Here, the mathematical correspondence between the KD and a specific stochastic differential equation (SDE) viewed from the perspective of the supersymmetric theory of stochastics (STS) is discussed. The STS is a novel, approximation-free framework to investigate SDEs. The correspondence reported here permits insights from the STS to be applied to the theory of KD and vice versa. It was previously known that the fast KD in the idealistic limit of no magnetic diffusion requires chaotic flows. The KD-STS correspondence shows that this is also true for the diffusive KD. From the STS perspective, the KD possesses a topological supersymmetry, and the dynamo effect can be viewed as its spontaneous breakdown. This supersymmetry breaking can be regarded as the stochastic generalization of the concept of dynamical chaos. As this supersymmetry breaking happens in both the diffusive and the nondiffusive cases, the necessity of the underlying SDE being chaotic is given in either case. The observed exponentially growing and oscillating KD modes prove physically that dynamical spectra of the STS evolution operator that break the topological supersymmetry exist with both real and complex ground state eigenvalues. Finally, we comment on the nonexistence of dynamos for scalar quantities.

  11. Dormancy Breaking in Ormosia arborea Seeds

    Directory of Open Access Journals (Sweden)

    Edilma Pereira Gonçalves

    2011-01-01

    Full Text Available Ormosia arborea is a tree species planted in urban areas and used to restore degraded areas. Its seeds are dormant and propagation is difficult. This study compares different dormancy breaking methods and physiological seed quality and seedling production. The seeds were germinated in sand in the laboratory of the Universidade Estadual de Santa Cruz, Ilhéus, Bahia, Brazil. The following dormancy breaking treatments were applied: control (intact seeds, 100°C water immersion; boiling water immersion followed by 24 hours of soaking; scarification with number 100 and number 50 sandpaper opposite from root emergence; sulfuric acid immersion for 1 hour, 50, 45, and 30 minutes. Seed immersion in 100°C and boiling water did not break the dormancy. The study species showed a greater vigor of seedling when its seeds were submitted to treatments associated with tegument rupturing by sandpaper or sulfuric acid. On the other hand, seed scarification with sulfuric acid for 1 hour, 50, 45, and 30 minutes or sandpaper favored seed germination and vigor.

  12. The Beam Break-Up Numerical Simulator

    International Nuclear Information System (INIS)

    Beam Break-Up (BBU) is a severe constraint in accelerator design, limiting beam current and quality. The control of BBU has become the focus of much research in the design of the next generation collider, recirculating and linear induction accelerators and advanced accelerators. Determining the effect on BBU of modifications to cavities, the focusing elements or the beam is frequently beyond the ability of current analytic models. A computer code was written to address this problem. The Beam Break-Up Numerical Simulator (BBUNS) was designed to numerically solve for beam break-up (BBU) due to an arbitrary transverse wakefield. BBUNS was developed to be as user friendly as possible on the Cray computer series. The user is able to control all aspects of input and output by using a single command file. In addition, the wakefield is specified by the user and read in as a table. The program can model energy variations along and within the beam, focusing magnetic field profiles can be specified, and the graphical output can be tailored. In this note we discuss BBUNS, its structure and application. Included are detailed instructions, examples and a sample session of BBUNS. This program is available for distribution. 50 refs., 18 figs., 5 tabs

  13. Healthy breaks: tasty tips for the under fives

    OpenAIRE

    Public Health Agency

    2014-01-01

    Today the Public Health Agency is launching a new resource pack designed to assist nursery schools and playgroups deliver a healthy breaks scheme.All nursery schools and playgroups in Northern Ireland will receive the pack - 'Healthy breaks for pre-school children' - which includes a poster and information leaflets for parents explaining why a healthy break is so important for pre-school children and some tips and ideas for healthy nutritious breaks.Judith Hanvey, Regional Food in Schools Co-...

  14. An alternative mechanism for radioprotection by dimethyl sulfoxide. Possible facilitation of DNA double-strand break repair

    International Nuclear Information System (INIS)

    The radioprotective effects of dimethyl sulfoxide (DMSO) have been known for many years, and the suppression of hydroxyl (OH) radicals induced by ionizing radiation has been thought to be the main cause of this effect. However, the DMSO concentration used was very high, and might be toxic, in earlier studies. In the present study, we administered a lower, non-toxic concentration (0.5%, id est (i.e.), 64 mM) of DMSO before irradiation and examined its radioprotective effects. Colony formation assay and micronucleus assay showed significant radioprotective effects in Chinese hamster ovary (CHO), but not in xrs5, which is defective in the repair function of DNA double-strand breaks. The levels of phosphorylated H2AX and the formation of 53BP1 foci 15 minutes after irradiation, which might reflect initial DNA double-strand breaks, in DMSO-treated CHO cells were similar to those in non-treated cells, suggesting that the radioprotective effects were not attributable to the suppression of general indirect action in the lower concentration of DMSO. On the other hand, 2 hours after irradiation, the average number of 53BP1 foci, which might reflect residual DNA double-strand breaks, was significantly decreased in DMSO-treated CHO cells compared to non-treated cells. The results indicated that low concentration of DMSO exerts radioprotective effects through the facilitation of DNA double-strand break repair rather than through the suppression of indirect action. (author)

  15. Dormancy-Breaking Requirements and Germination for Seeds of Ostrya carpinifolia Scop.

    Directory of Open Access Journals (Sweden)

    Elias PIPINIS

    2014-06-01

    Full Text Available The present research aims at investigating the combined effects of warm stratification (WS+cold stratification (CS, and gibberellic acid (GA3+cold stratification (CS on breaking dormancy and germination in seeds of Ostrya carpinifolia. The seeds were subjected to WS (20-25 ºC for 0, 1 and 2 months and were subsequently cold stratified at 3-5 ºC for 0, 1, 2, 3 and 4 months (1st experiment. A further amount of seeds was treated with 500, 1000 or 2000 ppm GA3 for 30 hours and then cold stratified at 3-5 ºC for 0, 1, 2, 3 and 4 months (2nd experiment. No germination was observed in the seeds subjected to only WS (1 and 2 months or CS for 1 month indicating that the seeds of O. carpinifolia are dormant . A 4-month stratification (1 month WS+3 month CS or 4 month CS fully released dormancy and led to a high germination percentage (94.17 and 98.34% respectively in a short time (7.12 and 7.00 days respectively. Warm stratification treatment prior to CS, was not required in order to break the seed dormancy of O. carpinifolia and also did not reduce the length of the (total stratification period required for breaking seed dormancy. Gibberellic acid (GA3 application entirely replaced the CS period required for breaking seed dormancy. The germination of the seeds treated only with 2000 ppm GA3 (0 months of CS was (94.17% as high as the germination of the seeds subjected to 4 months of CS (98.34%. It is obvious that the seedcoat of O. carpinifolia seeds was permeable to GA3 and did not mechanically restrict embryo growth, thus, the seeds did not exhibit physical dormancy. Based on dormancy breaking requirements, the O. carpinifolia seeds displayed intermediate physiological dormancy.

  16. 9 CFR 590.522 - Breaking room operations.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Breaking room operations. 590.522..., Processing, and Facility Requirements § 590.522 Breaking room operations. (a) The breaking room shall be kept... room personnel shall wash their hands thoroughly with odorless soap and water each time they enter...

  17. A strict QCD inequality and mechanisms for chiral symmetry breaking

    International Nuclear Information System (INIS)

    A strict QCD inequality allows one to discuss mechanisms proposed for breaking the chiral symmetry in QCD. ''Order parameters'' are identified such that if sufficiently many gauge field configurations contribute to them, spontaneous chiral symmetry breaking follows. As an application the role of instantons is discussed in chiral symmetry breaking in QCD. (orig.)

  18. 24 CFR 982.315 - Family break-up.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Family break-up. 982.315 Section... SECTION 8 TENANT BASED ASSISTANCE: HOUSING CHOICE VOUCHER PROGRAM Leasing a Unit § 982.315 Family break-up... assistance in the program if the family breaks up. The PHA administrative plan must state PHA policies on...

  19. Breaking of Waves over a Steep Bottom Slope

    DEFF Research Database (Denmark)

    Jensen, Morten S.

    The thesis deals with the wave breaking process of waves propagating over a steep submerged bottom slope. The amount of energy dissipated in the wave breaking process is focused upon. An extensive number of experimental tests (>400) using regular and irregular waves breaking over a simulated reef...

  20. Phenomenological approach to symmetry breaking pattern of democratic mass matrix

    CERN Document Server

    Harada, J

    2002-01-01

    We investigate the symmetry breaking pattern of the democratic mass matrix model, which leads to the small flavor mixing in quark sector and bi-large mixing in lepton sector. We present the symmetry breaking matrices in quark sector which are determined by alternative ways instead of conventional ansatz. These matrices might be useful for understanding the origin of democratic symmetry and its breaking.

  1. Familial hypercholesterolaemia in children and adolescents

    DEFF Research Database (Denmark)

    Wiegman, Albert; Gidding, Samuel S; Watts, Gerald F;

    2015-01-01

    Familial hypercholesterolaemia (FH) is a common genetic cause of premature coronary heart disease (CHD). Globally, one baby is born with FH every minute. If diagnosed and treated early in childhood, individuals with FH can have normal life expectancy. This consensus paper aims to improve awarenes...... management, we call for further studies in the young. Increased awareness, early identification, and optimal treatment from childhood are critical to adding decades of healthy life for children and adolescents with FH....

  2. Break Lines, Break lines were captured from Orthoimagery from our 1998 imagery, Published in unknown, Johnson County AIMS.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Break Lines dataset, was produced all or in part from Orthoimagery information as of unknown. It is described as 'Break lines were captured from Orthoimagery...

  3. On the application of symmetry breaking and its restoration to treat pairing correlation in finite nuclei

    CERN Document Server

    Hupin, Guillaume

    2012-01-01

    An alternative approach to symmetry restoration within Energy Density Functional, the Symmetry-Conserving EDF is discussed. In this approach, the energy is directly written in terms of the degrees of freedom encoded in the one-, two-... body density matrices of the state having good quantum numbers. The SC-EDF framework is illustrated within Projection After and Before variation applied to particle number restoration.

  4. Treating Influenza (Flu)

    Science.gov (United States)

    ... can be used to treat influenza illness. Antiviral drugs fight influenza viruses in your body. They are different from ... chills and fatigue. Your doctor may prescribe antiviral drugs to treat your flu illness. Should Istill get aflu vaccine? Yes. Antiviral ...

  5. How Is Pneumonia Treated?

    Science.gov (United States)

    ... page from the NHLBI on Twitter. How Is Pneumonia Treated? Treatment for pneumonia depends on the type ... can go back to their normal routines. Bacterial Pneumonia Bacterial pneumonia is treated with medicines called antibiotics. ...

  6. Adolescent childbearing.

    Science.gov (United States)

    Vernon, M

    1991-05-01

    The concern for the consequences of adolescent pregnancy are discussed. Childbirth among unmarried teenagers results in a higher incidence of low birth weight babies, a higher infant mortality and morbidity rate, a higher percentage of childbirth complications, a decreased likelihood of completing school, a higher risk of unemployment and welfare dependency, limited vocational opportunities, larger families, and vulnerability to psychological problems and distress. In 1988, 66% of all births to teens occurred outside of marriage. Out of wedlock live births to teens 14 years rose from 80.8% in 1970 to 92.5% in 1986, and for teens 15-19 years, 29.5% to 60.8%. 70% have a repeat pregnancy within the 1st year following their 1st childbirth. 50% have a 2nd child within 3 years. Most 2nd pregnancies occur in teenagers who are not using effective contractive methods, and the pregnancy is frequently unplanned and unwanted. The factors affecting the rate of 2nd pregnancy are age, race, marital status, education, and economic status. Teenage mothers tend to come from disadvantaged backgrounds, and childbearing compounds the poverty. Aid to families with dependent children 50% of payments were to teen mothers for the birth of their 1st child. Teen fathers are usually low income providers. The public costs are high. Some teen fathers abandon their children after birth, but many are interested in supporting their child. Specific programs to help prepare fathers are needed. Teenage mothers are stressed by child care arrangements, living arrangements, employment, school, relationships with peers, relationships with parents, housework and errands, health, finances, job counseling, community services, and child care information. Parents play an important role in guiding sexual involvement and early childbearing, and need to understand why teens get pregnant and to keep channels of communication open. Teens are influenced by media, peer pressure, lack of self-esteem, unhappiness

  7. Repeated alcohol administration during adolescence causes changes in the mesolimbic dopaminergic and glutamatergic systems and promotes alcohol intake in the adult rat.

    Science.gov (United States)

    Pascual, Maria; Boix, Jordi; Felipo, Vicente; Guerri, Consuelo

    2009-02-01

    Adolescence is a developmental period which the risk of drug and alcohol abuse increases. Since mesolimbic dopaminergic system undergoes developmental changes during adolescence, and this system is involved in rewarding effects of drugs of abuse, we addressed the hypothesis that ethanol exposure during juvenile/adolescent period over-activates mesolimbic dopaminergic system inducing adaptations which can trigger long-term enduring behavioural effects of alcohol abuse. We treated juvenile/adolescent or adult rats with ethanol (3 g/kg) for two-consecutive days at 48-h intervals over 14-day period. Here we show that intermittent ethanol treatment during the juvenile/adolescence period alters subsequent ethanol intake. In vivo microdialysis demonstrates that ethanol elicits a similar prolonged dopamine response in the nucleus accumbens of both adolescent and adult animals pre-treated with multiple doses of ethanol, although the basal dopamine levels were higher in ethanol-treated adolescents than in adult-treated animals. Repeated ethanol administration also down-regulates the expression of DRD2 and NMDAR2B phosphorylation in prefrontal cortex of adolescent animals, but not of adult rats. Finally, ethanol treatment during adolescence changes the acetylation of histones H3 and H4 in frontal cortex, nucleus accumbens and striatum, suggesting chromatin remodelling changes. In summary, our findings demonstrate the sensitivity of adolescent brain to ethanol effects on dopaminergic and glutamatergic neurotransmission, and suggest that abnormal plasticity in reward-related processes and epigenetic mechanisms could contribute to the vulnerability of adolescents to alcohol addiction. PMID:19077056

  8. Depression in adolescence

    OpenAIRE

    Thapar, Anita; Collishaw, Stephan; Pine, Daniel S.; Thapar, Ajay K

    2012-01-01

    Unipolar depressive disorder in adolescence is common worldwide but often unrecognised. The incidence, notably in girls, rises sharply after puberty and, by the end of adolescence, the 1 year prevalence rate exceeds 4%. The burden is highest in low-income and middle-income countries. Depression is associated with sub stantial present and future morbidity, and heightens suicide risk. The strongest risk factors for depression in adolescents are a family history of depression and exposure to psy...

  9. Chronic diseases in adolescence

    OpenAIRE

    Rončević Nevenka; Stojadinović Aleksandra; Odri Irena

    2006-01-01

    Introduction. The prevalence of chronic diseases in adolescence is constantly increasing, especially in the last two decades. Adolescence is a period of important changes: body growth and development, sexual development, development of cognitive abilities, change in family relations and between peers, formation of personal identity and personal system of values, making decisions on future occupation etc. Chronic diseases in adolescence. Chronic disorders affect all development issues and repr...

  10. Adolescence and Society

    OpenAIRE

    Fetihi, Leyla; Marmara Üniversitesi, Atatürk Eğitim Fakültesi, İlköğretim Bölümü

    2002-01-01

    Adolescence is quite a difficult and important developmental period of human lifecycle. Today going through adolescence is much more difficult than it was in the past. Adolescents are under the influence of various positive and negative factors, and they are growing up on their own mostly. Some of the problems of this period can be listed as drug use and addiction, high rates of crime, sex, sexual diseases, alcohol, smoking, traffic accidents, communication problems with parents, peer group p...

  11. ADOLESCENTS AND ALCOHOL

    OpenAIRE

    SPEAR, LINDA PATIA

    2013-01-01

    The high levels of alcohol consumption characteristic of adolescence may be in part biologically based, given that elevated consumption levels are also evident during this developmental transition in other mammalian species as well. Studies conducted using a simple animal model of adolescence in the rat has shown adolescents to be more sensitive than adults to social facilitatory and rewarding effects of alcohol, but less sensitive to numerous alcohol effects that may serve as cues to limit i...

  12. Effect of MDMA (ecstasy) on activity and cocaine conditioned place preference in adult and adolescent rats

    OpenAIRE

    Åberg, Maria; Wade, Dean; Wall, Erin; Izenwasser, Sari

    2006-01-01

    MDMA (ecstasy) is a drug commonly used in adolescence, and many users of MDMA also use other illicit drugs. It is not known whether MDMA during adolescence alters subsequent responses to cocaine differently than in adults. This study examined the effects of MDMA in adolescent and adult rats on cocaine conditioned reward. At the start of these experiments, adolescent rats were at postnatal day (PND) 33 and adult rats at PND 60. Each rat was treated for seven days with MDMA (2 or 5 mg/kg/day or...

  13. First empirical evaluation of outcomes for mentalization-based group therapy for adolescents with BPD

    DEFF Research Database (Denmark)

    Bo, Sune; Sharp, Carla; Beck, Emma;

    2016-01-01

    -based group therapy. Twenty-five adolescents completed the study of which the majority (23 out of 25) displayed improvement regarding borderline symptoms, depression, self-harm, peer-attachment, parent-attachment, mentalizing, and general psychopathology. Enhanced trust in peers and parents in combination......Adolescent Borderline Personality Disorder (BPD) is a devastating disorder, and it is essential to identify and treat the disorder in its early course. A total of 34 female Danish adolescents aged 15 to 18 years with BPD and sub-threshold BPD participated in one year of structured mentalization......-format mentalization- based treatment for adolescents with borderline traits....

  14. Treating Adolescent Obesity: A Pilot Project in a School.

    Science.gov (United States)

    Zakus, Gloria; And Others

    1981-01-01

    A weight control program for a group of eighth-grade girls, which included learning disabled students, was developed to change eating, exercise, and behavior patterns. The course included dietary management, physical activity, and behavior modification techniques. Results show that the students participating in the program decreased their weight…

  15. Baixa renda como fator de proteção contra asma em crianças e adolescentes usuários do Sistema Único de Saúde Low income as a protective factor against asthma in children and adolescents treated via the Brazilian Unified Health System

    Directory of Open Access Journals (Sweden)

    Murilo Carlos Amorim de Britto

    2008-05-01

    -off points related to the national minimum wage (R$350.00: 50% of minimum wage = satisfactory income (23.7% of the sample. There was no association between poverty and development of asthma. CONCLUSIONS: Poverty is not protective against asthma in children and adolescents treated via the Brazilian Unified Health System, as we might suppose based on the hygiene hypothesis. However, cohort studies are needed in order to confirm these findings.

  16. Group therapy for adolescents

    Directory of Open Access Journals (Sweden)

    Nada Hribar

    2001-03-01

    Full Text Available The group included adolescents from secondary school and some students. The group had weekly sessions or twice on mounth. The adolescents had varied simptoms: depressive, anxiety, psychosomatic disorders, learning difficulties, cunduct problems. All of adolescents were common on many problems in social interactions. The goal of therapeutic work were: to increase assertiveness skills and to reduce the anxious in social situations. The adolescents in group raised a self-esteem and developed some assertiveness skills: eye contact" and effective communication skills, persistence, refusing and requesting, giving and receiving critism, etc. The methods of work and techniques were based on principles of cognitive-behaviour therapy.

  17. Chronic diseases in adolescence

    Directory of Open Access Journals (Sweden)

    Rončević Nevenka

    2006-01-01

    Full Text Available Introduction. The prevalence of chronic diseases in adolescence is constantly increasing, especially in the last two decades. Adolescence is a period of important changes: body growth and development, sexual development, development of cognitive abilities, change in family relations and between peers, formation of personal identity and personal system of values, making decisions on future occupation etc. Chronic diseases in adolescence. Chronic disorders affect all development issues and represent an additional burden for adolescents. The interaction between chronic disorders and various development issues is complex and two-way: the disease may affect development, and development may affect the disease. Developmental, psychosocial and family factors are of great importance in the treatment of adolescents with chronic disorders. Chronic disorders affect all aspects of adolescent life, including relations with peers, school, nutrition, learning, traveling, entertainment, choice of occupation, plans for the future. Physicians should keep in mind that chronic diseases and their treatment represent only one aspect of person's life. Adolescents with chronic diseases have other needs as well, personal priorities, social roles and they expect these needs to be recognized and respected. Adolescent health care should be adjusted to the life style of adolescents.

  18. Repair of DNA double-strand breaks in Escherichia coli cells requires synthesis of proteins that can be induced by UV light

    International Nuclear Information System (INIS)

    The repair of DNA double-strand breaks in Escherichia coli cells irradiated with γ rays occurs only after new proteins are synthesized in response to damage introduced in the genome DNA. One protein whose synthesis is thus induced is the recA protein, and previous work has shown that recA- cells do not repair double-strand breaks. However, inducing recA protein by treating cells with nalidixic acid does not induce repair of double-strand breaks, so this repair requires more than the presence of the recA protein. When repair of double-strand breaks is blocked, the genome DNA is degraded by an endonuclease-like action. Evidence is presented to show that the inducible inhibition of DNA degradation after x-irradiation [Pollard, E.C. and Randall, E.P. (1973) Radiat. Res. 55, 265] is probably caused by the inducible repair of DNA double-strand breaks

  19. Sparticle spectrum and constraints in anomaly mediated supersymmetry breaking models

    CERN Document Server

    Huitu, K; Pandita, P N

    2002-01-01

    We study in detail the particle spectrum in anomaly mediated supersymmetry breaking models in which supersymmetry breaking terms are induced by super-Weyl anomaly. We investigate the minimal anomaly mediated supersymmetry breaking models, gaugino assisted supersymmetry breaking models, as well as models with additional residual non-decoupling D-term contributions due to an extra U(1) gauge symmetry at high energy scale. We derive sum rules for the sparticle masses in these models which can help in differentiating between them. We also obtain the sparticle spectrum numerically, and compare and contrast the results so obtained for the different types of anomaly mediated supersymmetry breaking models.

  20. Raman amplification in the coherent wave-breaking regime.

    Science.gov (United States)

    Farmer, J P; Pukhov, A

    2015-12-01

    In regimes far beyond the wave-breaking threshold of Raman amplification, we show that significant amplification can occur after the onset of wave breaking, before phase mixing destroys the coherent coupling between pump, probe, and plasma wave. Amplification in this regime is therefore a transient effect, with the higher-efficiency "coherent wave-breaking" (CWB) regime accessed by using a short, intense probe. Parameter scans illustrate the marked difference in behavior between below wave breaking, in which the energy-transfer efficiency is high but total energy transfer is low, wave breaking, in which efficiency is low, and CWB, in which moderate efficiencies allow the highest total energy transfer. PMID:26764840

  1. Extinction during memory reconsolidation blocks recovery of fear in adolescents.

    Science.gov (United States)

    Johnson, D C; Casey, B J

    2015-01-01

    Adolescence is a time of intensified emotional experiences, during which anxiety and stress-related disorders peak. The most effective behavioral therapies for treating these disorders share exposure-based techniques as a core component. Exposure-based therapies build on the principles of fear extinction learning and involve desensitizing the individual to cues that trigger anxiety. Yet, recent evidence shows an adolescent-specific diminished capacity to extinguish fear responses, suggesting that adolescents may respond less well to exposure-based therapies than other age groups. Here we demonstrate an alternative method for blocking the recall of fear memories in adolescents, building on principles of memory reconsolidation in adults. During memory reconsolidation, a memory that is recalled becomes labile during which time it can be updated. Prior research has shown that extinction training during memory reconsolidation attenuates the recovery of fear memory in human adults and in rodents. Using this method, we show attenuation of fear memory in adolescent humans. These findings have significant implications for treating one of the most vulnerable populations to anxiety and stress related disorders - adolescents - by optimizing exposure therapy based on principles of memory reconsolidation. PMID:25749583

  2. Adolescent physical activity and health: a systematic review.

    Science.gov (United States)

    Hallal, Pedro C; Victora, Cesar G; Azevedo, Mario R; Wells, Jonathan C K

    2006-01-01

    Physical activity in adolescence may contribute to the development of healthy adult lifestyles, helping reduce chronic disease incidence. However, definition of the optimal amount of physical activity in adolescence requires addressing a number of scientific challenges. This article reviews the evidence on short- and long-term health effects of adolescent physical activity. Systematic reviews of the literature were undertaken using a reference period between 2000 and 2004, based primarily on the MEDLINE/PubMed database. Relevant studies were identified by examination of titles, abstracts and full papers, according to inclusion criteria defined a priori. A conceptual framework is proposed to outline how adolescent physical activity may contribute to adult health, including the following pathways: (i) pathway A--tracking of physical activity from adolescence to adulthood; (ii) pathway B--direct influence of adolescent physical activity on adult morbidity; (iii) pathway C--role of physical activity in treating adolescent morbidity; and (iv) pathway D - short-term benefits of physical activity in adolescence on health. The literature reviews showed consistent evidence supporting pathway 'A', although the magnitude of the association appears to be moderate. Thus, there is an indirect effect on all health benefits resulting from adult physical activity. Regarding pathway 'B', adolescent physical activity seems to provide long-term benefits on bone health, breast cancer and sedentary behaviours. In terms of pathway 'C', water physical activities in adolescence are effective in the treatment of asthma, and exercise is recommended in the treatment of cystic fibrosis. Self-esteem is also positively affected by adolescent physical activity. Regarding pathway 'D', adolescent physical activity provides short-term benefits; the strongest evidence refers to bone and mental health. Appreciation of different mechanisms through which adolescent physical activity may influence adult

  3. Detection of strand breaks in phiX 174 RFI and PM2 DNA reacted with ultimate and proximate carcinogens.

    Science.gov (United States)

    Thielmann, H W

    1977-10-01

    Supercoiled DNA duplexes of phages phiX 174 and PM2 were treated in aqueous solution at neutral pH with ultimate and proximate carcinogens. Subsequently, the carcinogen-treated phage DNAs were subjected to velocity sedimentation in neutral and alkaline sucrose to quantitative introduction of single strand breaks. Reaction of phage DNA with the ultimate carcinogens N-methyl-N-nitrosourea (MeNOUr), N-ethyl-N-nitrosourea (EtNOUr), 7-bromomethyl-benza[a]-anthracene, N-acetoxy-2-acetylaminofluorene [(Ac)2ONFln] and K-region oxides for short periods followed by sedimentation in neutral sucrose gradients led to very few breaks. Incubation with the proximate carcinogens N-hydroxy-2-acetylaminofluorene, 2-acetylaminofluorene, 7-methyl-, and 7,12-dimethyl-benza[a]anthracene did not result in breaks. However, when the phage DNAs were reacted with the ultimate carcinogens under the same conditions but subsequently alkali-denatured and sedimented in alkaline sucrose gradients, single strand breaks were readily introduced. Incubation with the proximate carcinogens followed by alkali denaturation and sedimentation in alkaline sucrose showed that only 7,12-dimethyl-benz[a]anthracene and, to a minor extent, 7-methyl-benz[]anthracene caused alkali-inducible breaks. The ability of N-methyl-N'-nitro-N-nitrosoguanidine to effect breakdown of superhelical phage DNA in alkali was found enhanced in the presence of N-acetyl-cysteine. PMID:145749

  4. Fuel breaks affect nonnative species abundance in Californian plant communities

    Science.gov (United States)

    Merriam, K.E.; Keeley, J.E.; Beyers, J.L.

    2006-01-01

    We evaluated the abundance of nonnative plants on fuel breaks and in adjacent untreated areas to determine if fuel treatments promote the invasion of nonnative plant species. Understanding the relationship between fuel treatments and nonnative plants is becoming increasingly important as federal and state agencies are currently implementing large fuel treatment programs throughout the United States to reduce the threat of wildland fire. Our study included 24 fuel breaks located across the State of California. We found that nonnative plant abundance was over 200% higher on fuel breaks than in adjacent wildland areas. Relative nonnative cover was greater on fuel breaks constructed by bulldozers (28%) than on fuel breaks constructed by other methods (7%). Canopy cover, litter cover, and duff depth also were significantly lower on fuel breaks constructed by bulldozers, and these fuel breaks had significantly more exposed bare ground than other types of fuel breaks. There was a significant decline in relative nonnative cover with increasing distance from the fuel break, particularly in areas that had experienced more numerous fires during the past 50 years, and in areas that had been grazed. These data suggest that fuel breaks could provide establishment sites for nonnative plants, and that nonnatives may invade surrounding areas, especially after disturbances such as fire or grazing. Fuel break construction and maintenance methods that leave some overstory canopy and minimize exposure of bare ground may be less likely to promote nonnative plants. ?? 2006 by the Ecological Society of America.

  5. Break spectrum analyses for small break loss of coolant accidents in a RESAR-3S Plant

    International Nuclear Information System (INIS)

    A series of thermal-hydraulic analyses were performed to investigate phenomena occurring during small break loss-of-coolant-accident (LOCA) sequences in a RESAR-3S pressurized water reactor. The analysis included simulations of plant behavior using the TRAC-PF1 and RELAP5/MOD2 computer codes. Series of calculations were performed using both codes for different break sizes. The analyses presented here also served an audit function in that the results shown here were used by the US Nuclear Regulatory Commission (NRC) as an independent confirmation of similar analyses performed by Westinghouse Electric Company using another computer code. 10 refs., 62 figs., 14 tabs

  6. Conflict Resolution in Parent-Adolescent Relationships and Adolescent Delinquency

    Science.gov (United States)

    Van Doorn, Muriel D.; Branje, Susan J. T.; Meeus, Wim H. J.

    2008-01-01

    This study examines the relation between conflict resolution styles in parent-adolescent relationships and adolescent delinquency. Questionnaires about conflict resolution styles were completed by 284 early adolescents (mean age 13.3) and their parents. Adolescents also completed a questionnaire on delinquency. Hierarchical regression analyses…

  7. Cascading Multicriticality in Nonrelativistic Spontaneous Symmetry Breaking

    CERN Document Server

    Griffin, Tom; Horava, Petr; Yan, Ziqi

    2015-01-01

    Without Lorentz invariance, spontaneous global symmetry breaking can lead to multicritical Nambu-Goldstone modes with a higher-order low-energy dispersion $\\omega\\sim k^n$ ($n=2,3,\\ldots$), whose naturalness is protected by polynomial shift symmetries. Here we investigate the role of infrared divergences and the nonrelativistic generalization of the Coleman-Hohenberg-Mermin-Wagner (CHMW) theorem. We find novel cascading phenomena with large hierarchies between the scales at which the value of $n$ changes, leading to an evasion of the "no-go" consequences of the relativistic CHMW theorem.

  8. Heavy quark solitons strangeness and symmetry breaking

    CERN Document Server

    Momen, A; Subbaraman, A; Momen, Arshad; Schechter, Joseph; Subbaraman, Anand

    1994-01-01

    We discuss the generalization of the Callan-Klebanov model to the case of heavy quark baryons. The light flavor group is considered to be $SU(3)$ and the limit of heavy spin symmetry is taken. The presence of the Wess-Zumino-Witten term permits the neat development of a picture , at the collective level, of a light diquark bound to a ``heavy" quark with decoupled spin degree of freedom. The consequences of $SU(3)$ symmetry breaking are discussed in detail. We point out that the $SU(3)$ mass splittings of the heavy baryons essentially measure the ``low energy" physics once more and that the comparison with experiment is satisfactory.

  9. Heavy quark solitons: Strangeness and symmetry breaking

    International Nuclear Information System (INIS)

    We discuss the generalization of the Callan-Klebanov model to the case of heavy quark baryons. The light flavor group is considered to be SU(3) and the limit of heavy spin symmetry is taken. The presence of the Wess-Zumino-Witten term permits the neat development of a picture, at the collective level, of a light diquark bound to a ''heavy'' quark with decoupled spin degree of freedom. The consequences of SU(3) symmetry breaking are discussed in detail. We point out that the SU(3) mass splitting of the heavy baryons essentially measure the ''low energy'' physics once more and that the comparison with experiment is satisfactory

  10. Breaking the fault tree circular logic

    International Nuclear Information System (INIS)

    Event tree - fault tree approach to model failures of nuclear plants as well as of other complex facilities is noticeably dominant now. This approach implies modeling an object in form of unidirectional logical graph - tree, i.e. graph without circular logic. However, genuine nuclear plants intrinsically demonstrate quite a few logical loops (circular logic), especially where electrical systems are involved. This paper shows the incorrectness of existing practice of circular logic breaking by elimination of part of logical dependencies and puts forward a formal algorithm, which enables the analyst to correctly model the failure of complex object, which involves logical dependencies between system and components, in form of fault tree. (author)

  11. Spontaneous symmetry breaking in a classical particle

    CERN Document Server

    Sánchez, L A; Sanchez, Luis Alberto; Mahecha, Jorge

    2003-01-01

    Due to the fact that only matter fields have phase, frequently is believed that the gauge principle can induce gauge fields only in quantum systems. But this is not necessary. This paper, of pedagogical scope, presents a classical system constituted by a particle in a classical potential, which is used as a model to illustrate the gauge principle and the spontaneous symmetry breaking. Those concepts appear in the study of second order phase transitions. Ferroelectricity, ferromagnetism, superconductivity, plasmons in a free electron gas, and the mass of vector bosons in the gauge field Yang-Mills theories, are some of the phenomena in which these transitions occur.

  12. String breaking in four dimensional lattice QCD

    International Nuclear Information System (INIS)

    Virtual quark pair screening leads to breaking of the string between fundamental representation quarks in QCD. For unquenched four dimensional lattice QCD, this (so far elusive) phenomenon is studied using the recently developed truncated determinant algorithm (TDA). The dynamical configurations were generated on a 650 MHz PC. Quark eigenmodes up to 420 MeV are included exactly in these TDA studies performed at low quark mass on large coarse [but O(a2) improved] lattices. A study of Wilson line correlators in Coulomb gauge extracted from an ensemble of 1000 two-flavor dynamical configurations reveals evidence for flattening of the string tension at distances R∼>1 fm

  13. String Breaking in Four Dimensional Lattice QCD

    CERN Document Server

    Duncan, A; Thacker, H

    2001-01-01

    Virtual quark pair screening leads to breaking of the string between fundamental representation quarks in QCD. For unquenched four dimensional lattice QCD, this (so far elusive) phenomenon is studied using the recently developed truncated determinant algorithm (TDA). The dynamical configurations were generated on an Athlon 650 MHz PC. Quark eigenmodes up to 420 MeV are included exactly in these TDA studies performed at low quark mass on large coarse (but O($a^2$) improved) lattices. A study of Wilson line correlators in Coulomb gauge extracted from an ensemble of 1000 two-flavor dynamical configurations reveals evidence for flattening of the string tension at distances R $\\geq$ approximately 1 fm.

  14. SU(3) flavour breaking and baryon structure

    Energy Technology Data Exchange (ETDEWEB)

    Cooke, A.N.; Horsley, R. [Edinburgh Univ. (United Kingdom). School of Physics and Astronomy; Nakamura, Y. [RIKEN Advanced Institute for Computational Science, Kobe, Hyogo (Japan); Pleiter, D. [Forschungszentrum Juelich GmbH (Germany). Juelich Supercomputing Centre (JSC); Regensburg Univ. (Germany). Institut fuer Theoretische Physik; Rakow, P.E.L. [Liverpool Univ. (United Kingdom). Theoretical Physics Div.; Shanahan, P.; Zanotti, J.M. [Adelaide Univ., SA (Australia). CSSM, School of Chemistry and Physics; Schierholz, G. [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Stueben, H. [Hamburg Univ. (Germany). Regionales Rechenzentrum; Collaboration: QCDSF/UKQCD Collaboration

    2013-11-15

    We present results from the QCDSF/UKQCD collaboration for hyperon electromagnetic form factors and axial charges obtained from simulations using N{sub f}=2+1 flavours of O(a)-improved Wilson fermions. We also consider matrix elements relevant for hyperon semileptonic decays. We find flavour-breaking effects in hyperon magnetic moments which are consistent with experiment, while our results for the connected quark spin content indicates that quarks contribute more to the spin of the {Xi} baryon than they do to the proton.

  15. New Mechanisms For Transmission Of Supersymmetry Breaking

    CERN Document Server

    Ng, S P

    2004-01-01

    We considered new mechanisms for transmission of supersymmetry breaking and their phenomenological consequences. Specifically, we investigated the scalar mass corrections via five-dimensional supergravity loops and explored the possibility that supersymmetry is an accidental symmetry of Nature. We find that both these lead to phenomenologically viable scenarios. In the former, the negative slepton mass-squared masses arising from minimal anomaly mediation is cured. In the latter, which constitutes a paradigm shift, we find a more natural framework for low-energy supersymmetry than the conventional picture.

  16. Breaking Barriers in Polymer Additive Manufacturing

    Energy Technology Data Exchange (ETDEWEB)

    Love, Lonnie J [ORNL; Duty, Chad E [ORNL; Post, Brian K [ORNL; Lind, Randall F [ORNL; Lloyd, Peter D [ORNL; Kunc, Vlastimil [ORNL; Peter, William H [ORNL; Blue, Craig A [ORNL

    2015-01-01

    Additive Manufacturing (AM) enables the creation of complex structures directly from a computer-aided design (CAD). There are limitations that prevent the technology from realizing its full potential. AM has been criticized for being slow and expensive with limited build size. Oak Ridge National Laboratory (ORNL) has developed a large scale AM system that improves upon each of these areas by more than an order of magnitude. The Big Area Additive Manufacturing (BAAM) system directly converts low cost pellets into a large, three-dimensional part at a rate exceeding 25 kg/h. By breaking these traditional barriers, it is possible for polymer AM to penetrate new manufacturing markets.

  17. Dynamical supersymmetry breaking at low energies

    CERN Document Server

    Dine, Michael; Dine, Michael; Nelson, Ann E.

    1993-01-01

    Conventional approaches to supersymmetric model building suffer from several naturalness problems: they do not explain the large hierarchy between the weak scale and the Planck mass, and they require fine tuning to avoid large flavor changing neutral currents and particle electric dipole moments. The existence of models with dynamical supersymmetry breaking, which can explain the hierarchy, has been known for some time, but efforts to build such models have suffered from unwanted axions and difficulties with asymptotic freedom. In this paper, we describe an approach to model building with supersymmetry broken at comparatively low energies which solves these problems, and give a realistic example.

  18. Dynamical supersymmetry breaking at low energies

    International Nuclear Information System (INIS)

    Conventional approaches to supersymmetric model building suffer from several naturalness problems: they do not explain the large hierarchy between the weak scale and the Planck mass, and they require fine-tuning to avoid large flavor-changing neutral currents and particle electric dipole moments. The existence of models with dynamical supersymmetry breaking, which can explain the hierarchy, has been known for some time, but efforts to build such models have suffered from unwanted axions and difficulties with asymptotic freedom. In this paper we describe an approach to model building with supersymmetry broken at comparatively low energies which solves these problems, and give a realistic example

  19. Cosmological SUSY Breaking and the Pyramid Schemes

    CERN Document Server

    Banks, T

    2014-01-01

    I review the ideas of holographic space-time (HST), Cosmological SUSY breaking (CSB), and the Pyramid Schemes, which are the only known models of Tera-scale physics consistent with CSB, current particle data, and gauge coupling unification. There is considerable uncertainty in the estimate of the masses of supersymmetric partners of the standard model particles, but the model predicts that the gluino is probably out of reach of the LHC, squarks may be in reach, and the NLSP is a right handed slepton, which should be discovered soon.

  20. Percolation picture of nucleus break-up

    International Nuclear Information System (INIS)

    The production of nuclear fragments in multifragmentation and spallation reactions is viewed as a percolation phenomenon. A model of nuclear percolation is proposed. The criteria for linkage of nucleons to a cluster are defined in real and momentum spaces. In addition, ''compactness'' conditions are imposed to the clusters in both spaces. This model behaves in many respects as a two-dimensional site percolation model, exhibiting a rather well defined percolation threshold at psub(c) approximately 0.6. The concentration p is related to the number of fast particles leaving the nuclear volume. We discuss possible experimental signatures of this new break-up mechanism

  1. Postmodernism and Consumer Psychology: Transformation or Break?

    Directory of Open Access Journals (Sweden)

    Manel Hamouda

    2012-01-01

    Full Text Available The research’s aim is to identify the postmodern consumer characteristics. Studied through its main conditions (Hyperreality, Fragmentation, Decentered subject, Reversal of production and consumption and Paradoxical juxtaposition of opposites, postmodernism seems to affect some psychological traits of the consumer (Materialism, social desirability, locus of control and social identity. We tried to generate a number of assumptions. The check of these assumptions could answer us whether these psychological characteristics have been radically influenced by postmodernism and in this case, the consumer would have undergone a break or the effect is partial and it is only a simple transformation within the consumer.

  2. Implications of Local Chiral Symmetry Breaking

    CERN Document Server

    La, H S

    2003-01-01

    The spontaneous symmetry breaking of a local chiral symmetry to its diagonal vector symmetry naturally realizes a complete geometrical structure more general than that of Yang-Mills (YM) theory, rather similar to that of gravity. A good example is the Quantum Chromodynamics (QCD) with respect to the Chiral Color model. Also, a new anomaly-free particle content for a Chiral Color model is introduced: the Chiral Color can be realized without introducing whole new generations of quarks and leptons, but by simply enlarging each generation with new exotic fermions.

  3. Electroweak symmetry breaking beyond the Standard Model

    Indian Academy of Sciences (India)

    Gautam Bhattacharyya

    2012-10-01

    In this paper, two key issues related to electroweak symmetry breaking are addressed. First, how fine-tuned different models are that trigger this phenomenon? Second, even if a light Higgs boson exists, does it have to be necessarily elementary? After a brief introduction, the fine-tuning aspects of the MSSM, NMSSM, generalized NMSSM and GMSB scenarios shall be reviewed, then the little Higgs, composite Higgs and the Higgsless models shall be compared. Finally, a broad overview will be given on where we stand at the end of 2011.

  4. Low concentration of arsenite exacerbates UVR-induced DNA strand breaks by inhibiting PARP-1 activity.

    Science.gov (United States)

    Qin, Xu-Jun; Hudson, Laurie G; Liu, Wenlan; Timmins, Graham S; Liu, Ke Jian

    2008-10-01

    Epidemiological studies have associated arsenic exposure with many types of human cancers. Arsenic has also been shown to act as a co-carcinogen even at low concentrations. However, the precise mechanism of its co-carcinogenic action is unknown. Recent studies indicate that arsenic can interfere with DNA-repair processes. Poly(ADP-ribose) polymerase (PARP)-1 is a zinc-finger DNA-repair protein, which can promptly sense DNA strand breaks and initiate DNA-repair pathways. In the present study, we tested the hypothesis that low concentrations of arsenic could inhibit PAPR-1 activity and so exacerbate levels of ultraviolet radiation (UVR)-induced DNA strand breaks. HaCat cells were treated with arsenite and/or UVR, and then DNA strand breaks were assessed by comet assay. Low concentrations of arsenite (mechanism. Combination treatments of arsenite with PARP-1 inhibitor 3-aminobenzamide or PARP-1 siRNA demonstrate that PARP-1 is the target of arsenite. Together, these findings show that arsenite at low concentration exacerbates UVR-induced DNA strand breaks by inhibiting PARP-1 activity, which may represent an important mechanism underlying the co-carcinogenicity of arsenic. PMID:18619636

  5. Pathological Internet Use and Risk-Behaviors among European Adolescents

    Directory of Open Access Journals (Sweden)

    Tony Durkee

    2016-03-01

    Full Text Available Risk-behaviors are a major contributor to the leading causes of morbidity among adolescents and young people; however, their association with pathological Internet use (PIU is relatively unexplored, particularly within the European context. The main objective of this study is to investigate the association between risk-behaviors and PIU in European adolescents. This cross-sectional study was conducted within the framework of the FP7 European Union project: Saving and Empowering Young Lives in Europe (SEYLE. Data on adolescents were collected from randomized schools within study sites across eleven European countries. PIU was measured using Young’s Diagnostic Questionnaire (YDQ. Risk-behaviors were assessed using questions procured from the Global School-Based Student Health Survey (GSHS. A total of 11,931 adolescents were included in the analyses: 43.4% male and 56.6% female (M/F: 5179/6752, with a mean age of 14.89 ± 0.87 years. Adolescents reporting poor sleeping habits and risk-taking actions showed the strongest associations with PIU, followed by tobacco use, poor nutrition and physical inactivity. Among adolescents in the PIU group, 89.9% were characterized as having multiple risk-behaviors. The significant association observed between PIU and risk-behaviors, combined with a high rate of co-occurrence, underlines the importance of considering PIU when screening, treating or preventing high-risk behaviors among adolescents.

  6. Pathological Internet Use and Risk-Behaviors among European Adolescents.

    Science.gov (United States)

    Durkee, Tony; Carli, Vladimir; Floderus, Birgitta; Wasserman, Camilla; Sarchiapone, Marco; Apter, Alan; Balazs, Judit A; Bobes, Julio; Brunner, Romuald; Corcoran, Paul; Cosman, Doina; Haring, Christian; Hoven, Christina W; Kaess, Michael; Kahn, Jean-Pierre; Nemes, Bogdan; Postuvan, Vita; Saiz, Pilar A; Värnik, Peeter; Wasserman, Danuta

    2016-01-01

    Risk-behaviors are a major contributor to the leading causes of morbidity among adolescents and young people; however, their association with pathological Internet use (PIU) is relatively unexplored, particularly within the European context. The main objective of this study is to investigate the association between risk-behaviors and PIU in European adolescents. This cross-sectional study was conducted within the framework of the FP7 European Union project: Saving and Empowering Young Lives in Europe (SEYLE). Data on adolescents were collected from randomized schools within study sites across eleven European countries. PIU was measured using Young's Diagnostic Questionnaire (YDQ). Risk-behaviors were assessed using questions procured from the Global School-Based Student Health Survey (GSHS). A total of 11,931 adolescents were included in the analyses: 43.4% male and 56.6% female (M/F: 5179/6752), with a mean age of 14.89 ± 0.87 years. Adolescents reporting poor sleeping habits and risk-taking actions showed the strongest associations with PIU, followed by tobacco use, poor nutrition and physical inactivity. Among adolescents in the PIU group, 89.9% were characterized as having multiple risk-behaviors. The significant association observed between PIU and risk-behaviors, combined with a high rate of co-occurrence, underlines the importance of considering PIU when screening, treating or preventing high-risk behaviors among adolescents. PMID:27005644

  7. Pathological Internet Use and Risk-Behaviors among European Adolescents

    Science.gov (United States)

    Durkee, Tony; Carli, Vladimir; Floderus, Birgitta; Wasserman, Camilla; Sarchiapone, Marco; Apter, Alan; Balazs, Judit A.; Bobes, Julio; Brunner, Romuald; Corcoran, Paul; Cosman, Doina; Haring, Christian; Hoven, Christina W.; Kaess, Michael; Kahn, Jean-Pierre; Nemes, Bogdan; Postuvan, Vita; Saiz, Pilar A.; Värnik, Peeter; Wasserman, Danuta

    2016-01-01

    Risk-behaviors are a major contributor to the leading causes of morbidity among adolescents and young people; however, their association with pathological Internet use (PIU) is relatively unexplored, particularly within the European context. The main objective of this study is to investigate the association between risk-behaviors and PIU in European adolescents. This cross-sectional study was conducted within the framework of the FP7 European Union project: Saving and Empowering Young Lives in Europe (SEYLE). Data on adolescents were collected from randomized schools within study sites across eleven European countries. PIU was measured using Young’s Diagnostic Questionnaire (YDQ). Risk-behaviors were assessed using questions procured from the Global School-Based Student Health Survey (GSHS). A total of 11,931 adolescents were included in the analyses: 43.4% male and 56.6% female (M/F: 5179/6752), with a mean age of 14.89 ± 0.87 years. Adolescents reporting poor sleeping habits and risk-taking actions showed the strongest associations with PIU, followed by tobacco use, poor nutrition and physical inactivity. Among adolescents in the PIU group, 89.9% were characterized as having multiple risk-behaviors. The significant association observed between PIU and risk-behaviors, combined with a high rate of co-occurrence, underlines the importance of considering PIU when screening, treating or preventing high-risk behaviors among adolescents. PMID:27005644

  8. Do Adolescents Prefer Electronic Books to Paper Books?

    Directory of Open Access Journals (Sweden)

    Margaret K. Merga

    2015-11-01

    Full Text Available While electronic books offer a range of benefits and may be supposed to be more appealing to young people than paper books, this assumption is often treated as fact by educational researchers. Understanding adolescents’ true current preferences is essential, as incorrect assumptions can lead to decisions which restrict adolescent access to their preferred book mode. The belief that adolescents prefer electronic books to paper books has already led to some school libraries being expunged of paper books. As adolescents show a higher level of aliteracy than younger children, and regular reading offers a broad range of benefits for young people, it is imperative that school’s decisions around providing access to books are responsive to adolescent students’ genuine preferences. This paper analyses the current and relevant academic research around adolescent preferences for book modes, finding that, at present, the contention that adolescents prefer electronic books is not supported by the available research. In addition, there are a number of issues identified that make analyzing the findings in this area problematic. Future studies in this area are needed before an adolescent preference for electronic books can be unequivocally substantiated.

  9. Incidence of cervical intraepithelial lesions in a population of adolescents treated in public health services in Rio de Janeiro, Brazil Incidência de lesões intra-epiteliais cervicais em população de adolescentes atendidas em serviço público de saúde no Rio de Janeiro, Brasil

    Directory of Open Access Journals (Sweden)

    Denise Leite Maia Monteiro

    2009-05-01

    Full Text Available This study aimed to estimate the incidence and types of cervical cytopathological findings in adolescents who were treated in public health services between 1993 and 2006. This is a cohort study, with the following inclusion criteria: O objetivo foi estimar a incidência e os tipos das alterações citopatológicas cervicais em adolescentes acompanhadas em serviço público entre 1993-2006. Estudo de coorte, tendo como critérios de inclusão: idade < 20 anos, apresentar atividade sexual, citopatologia negativa para lesão cervical na entrada do estudo ou tempo de atividade sexual <1 ano. Os dados foram coletados de prontuários de 403 adolescentes. Foi estimada densidade de incidência, e para o cálculo da incidência das alterações citopatológicas referentes a cinco anos de acompanhamento após atividade sexual foi utilizado o método atuarial. No primeiro ano de atividade sexual, a incidência de lesões cervicais foi de 24,1%. Houve redução da incidência nos quatro anos subseqüentes com variação entre 3-8%. A densidade de incidência foi de 4,7 casos/100 pessoas-ano. O primeiro diagnóstico citológico anormal mostrou atipias em células escamosas de significado indeterminado (ASCUS em 5,5% (22 das pacientes, lesão intra-epitelial escamosa de baixo grau (LSIL em 28% (113 e lesão intra-epitelial escamosa de alto grau (HSIL em 3% (12. Oito (67% dos casos de HSIL ocorreram no primeiro ano de atividade sexual. A incidência de alterações citopatológicas é alta no início da vida sexual, sugerindo ser importante a inclusão das adolescentes sexualmente ativas no Programa de Controle do Câncer de Colo Uterino.

  10. Psychotherapeutic approaches to non-suicidal self-injury in adolescents

    Directory of Open Access Journals (Sweden)

    Washburn Jason J

    2012-03-01

    Full Text Available Abstract Non-suicidal self-injury (NSSI among adolescents is gaining increasing attention in both clinical and scientific arenas. The lifetime prevalence of NSSI is estimated to vary between 7.5% to 8% for preadolescents, increasing to between 12% and 23% for adolescents. Despite the prevalence and the increasing interest in NSSI, few psychotherapeutic treatments have been designed specifically for NSSI, and no treatments have been evaluated specifically for the treatment of NSSI among adolescents. Consequently, child and adolescent clinicians are left with little evidence-based guidance for treating this challenging population. To provide some guidance, evaluations of treatments for adults with NSSI and for adolescents with related conditions, such as deliberate self-harm and borderline personality disorder, are reviewed. Clinical guidelines and resources are also discussed to assist with the gaps in the knowledge base for treatment of NSSI among adolescents.

  11. Supersymmetry breaking in 4D string theory

    International Nuclear Information System (INIS)

    We construct a (locally supersymmetric) four-fermion effective lagrangian description of the strong binding effects responsible for the formation of a gaugino condensate, extending the analysis to include the multiple moduli of orbifold compactification. Using this to estimate the binding we find that supersymmetry is broken and a phenomenologically realistic value for the gravitino mass and gauge coupling constant at the unification scale with only one gaugino condensate may be obtained. The main source for supersymmetry breaking is the VEV of the auxiliary field of the dilaton hs (i.e. hS>>hT, where T are moduli fields). By studying the scalar potential we find either that the vacuum expectation values of the moduli have a common value related to the vacuum expectation value of the dilaton or that they take the values of the dual invariant points. A squeezed orbifold can thus naturally be obtained, allowing for the possibility of minimal string unification. We include chiral matter fields and derive the scalar potential up to one-loop level. The one-loop potential is responsible for stabilising the scalar potential for vanishing vacuum expectation values of the chiral matter fields. We then calculate the soft supersymmetry breaking parameters in the visible sector. Finally we show that with a suitable choice of superpotential it is possible to cancel the cosmological constant while having supersymmetry broken. ((orig.))

  12. On chiral symmetry breaking, topology and confinement

    Energy Technology Data Exchange (ETDEWEB)

    Shuryak, Edward

    2014-08-15

    We start with the relation between the chiral symmetry breaking and gauge field topology. New lattice results further enhance the notion of Zero Mode Zone, a very narrow strip of states with quasizero Dirac eigenvalues. Then we move to the issue of “origin of mass” and Brown–Rho scaling: a number of empirical facts contradicts to the idea that masses of quarks and such hadrons as ρ,N decrease near T{sub c}. We argue that while at T=0 the main contribution to the effective quark mass is chirally odd m{sub χ/}, near T{sub c} it rotates to chirally-even component m{sub χ}, because “infinite clusters” of topological solitons gets split into finite ones. Recent progress in understanding of topology require introduction of nonzero holonomy 〈A{sub 0}〉≠0, which splits instantons into N{sub c} (anti)selfdual “instanton–dyons”. Qualitative progress, as well as first numerical studies of the dyon ensemble are reported. New connections between chiral symmetry breaking and confinement are recently understood, since instanton–dyons generate holonomy potential with a minimum at confining value, if the ensemble is dense enough.

  13. Break-Induced Replication and Genome Stability

    Directory of Open Access Journals (Sweden)

    Anna Malkova

    2012-10-01

    Full Text Available Genetic instabilities, including mutations and chromosomal rearrangements, lead to cancer and other diseases in humans and play an important role in evolution. A frequent cause of genetic instabilities is double-strand DNA breaks (DSBs, which may arise from a wide range of exogeneous and endogeneous cellular factors. Although the repair of DSBs is required, some repair pathways are dangerous because they may destabilize the genome. One such pathway, break-induced replication (BIR, is the mechanism for repairing DSBs that possesses only one repairable end. This situation commonly arises as a result of eroded telomeres or collapsed replication forks. Although BIR plays a positive role in repairing DSBs, it can alternatively be a dangerous source of several types of genetic instabilities, including loss of heterozygosity, telomere maintenance in the absence of telomerase, and non-reciprocal translocations. Also, mutation rates in BIR are about 1000 times higher as compared to normal DNA replication. In addition, micro-homology-mediated BIR (MMBIR, which is a mechanism related to BIR, can generate copy-number variations (CNVs as well as various complex chromosomal rearrangements. Overall, activation of BIR may contribute to genomic destabilization resulting in substantial biological consequences including those affecting human health.

  14. Spontaneous spherical symmetry breaking in atomic confinement

    CERN Document Server

    Sveshnikov, K

    2016-01-01

    The effect of spontaneous breaking of initial SO(3) symmetry is shown to be possible for an H-like atom in the ground state, when it is confined in a spherical box under general boundary conditions of "not going out" through the box surface (i.e. third kind or Robin's ones), for a wide range of physically reasonable values of system parameters. The reason is that such boundary conditions could yield a large magnitude of electronic wavefunction in some sector of the box boundary, what in turn promotes atomic displacement from the box center towards this part of the boundary, and so the underlying SO(3) symmetry spontaneously breaks. The emerging Goldstone modes, coinciding with rotations around the box center, restore the symmetry by spreading the atom over a spherical shell localized at some distances from the box center. Atomic confinement inside the cavity proceeds dynamically -- due to the boundary condition the deformation of electronic wavefunction near the boundary works as a spring, that returns the at...

  15. Chip breaking system for automated machine tool

    Science.gov (United States)

    Arehart, Theodore A.; Carey, Donald O.

    1987-01-01

    The invention is a rotary selectively directional valve assembly for use in an automated turret lathe for directing a stream of high pressure liquid machining coolant to the interface of a machine tool and workpiece for breaking up ribbon-shaped chips during the formation thereof so as to inhibit scratching or other marring of the machined surfaces by these ribbon-shaped chips. The valve assembly is provided by a manifold arrangement having a plurality of circumferentially spaced apart ports each coupled to a machine tool. The manifold is rotatable with the turret when the turret is positioned for alignment of a machine tool in a machining relationship with the workpiece. The manifold is connected to a non-rotational header having a single passageway therethrough which conveys the high pressure coolant to only the port in the manifold which is in registry with the tool disposed in a working relationship with the workpiece. To position the machine tools the turret is rotated and one of the tools is placed in a material-removing relationship of the workpiece. The passageway in the header and one of the ports in the manifold arrangement are then automatically aligned to supply the machining coolant to the machine tool workpiece interface for breaking up of the chips as well as cooling the tool and workpiece during the machining operation.

  16. Spitzer View of Lyman Break Galaxies

    CERN Document Server

    Magdis, Georgios E

    2007-01-01

    Using a combination of deep MID-IR observations obtained by IRAC, MIPS and IRS on board Spitzer we investigate the MID-IR properties of Lyman Break Galaxies (LBGs) at z~3, establish a better understanding of their nature and attempt a complete characterisation of the population. With deep mid-infrared and optical observations of ~1000 LBGs covered by IRAC/MIPS and from the ground respectively, we extend the spectral energy distributions (SEDs) of the LBGs to mid-infrared. Spitzer data reveal for the first time that the mid-infrared properties of the population are inhomogeneous ranging from those with marginal IRAC detections to those with bright rest-frame near-infrared colors and those detected at 24mu MIPS band revealing the newly discovered population of the Infrared Luminous Lyman Break Galaxies (ILLBGs). To investigate this diversity, we examine the photometric properties of the population and we use stellar population synthesis models to probe the stellar content of these galaxies. We find that a fract...

  17. Hyperscaling violation and electroweak symmetry breaking

    International Nuclear Information System (INIS)

    We consider a class of simplified models of dynamical electroweak symmetry breaking built in terms of their five-dimensional weakly-coupled gravity duals, in the spirit of bottom-up holography. The sigma-model consists of two abelian gauge bosons and one real, non-charged scalar field coupled to gravity in five dimensions. The scalar potential is a simple exponential function of the scalar field. The background metric resulting from solving the classical equations of motion exhibits hyperscaling violation, at least at asymptotically large values of the radial direction. We study the spectrum of scalar composite states of the putative dual field theory by fluctuating the sigma-model scalars and gravity, and discuss in which cases we find a parametrically light scalar state in the spectrum. We model the spontaneous breaking of the (weakly coupled) gauge symmetry to the diagonal subgroup by the choice of IR boundary conditions. We compute the mass spectrum of spin-1 states, and the precision electroweak parameter S as a function of the hyperscaling coefficient. We find a general bound on the mass of the lightest spin-1 resonance, by requiring that the indirect bounds on the precision parameters be satisfied, that implies that precision electroweak physics excludes the possibility of a techni-rho meson with mass lighter than several TeV

  18. Smoking and adolescent health.

    Science.gov (United States)

    Park, Sang-Hee

    2011-10-01

    With the Westernization and opening of our society, adolescents' smoking is increasing and being popularized. Many adolescents start smoking at an early age out of curiosity and venturesomeness, and earlier start of smoking makes it more difficult to quit smoking. Adolescents' habitual smoking not only becomes a gateway to all kinds of substance abuse but also causes various health problems including upper respiratory infection, immature lung development, reduced maximum vital capacity, and lung cancer. Therefore, it is quite important to prevent adolescents from smoking. The lowering of adolescents' smoking rate cannot be achieved only through social restrictions such as stereotyped education on the harms of smoking and ID checking. In order to lower adolescents' smoking rate substantially, each area of society should develop standardized programs and make related efforts. As adolescents' smoking is highly influenced by home environment or school life, it is necessary to make efforts in effective education and social reinforcement in school, to establish related norms, and to execute preventive education using peer groups. When these efforts are spread throughout society in cooperation with homes and communities, they will be helpful to protect adolescents' health and improve their quality of life. PMID:22232621

  19. Inside the Adolescent Brain

    Science.gov (United States)

    Drury, Stacy S.

    2009-01-01

    Dr. Jay Giedd says that the main alterations in the adolescent brain are the inverted U-shaped developmental trajectories with late childhood/early teen peaks for gray matter volume among others. Giedd adds that the adolescent brain is vulnerable to substances that artificially modulate dopamine levels since its reward system is in a state of flux.

  20. Gender and Adolescent Development

    Science.gov (United States)

    Perry, David G.; Pauletti, Rachel E.

    2011-01-01

    This article summarizes and critiques recent trends in research and theory on the role of gender in adolescent development. First, gender differences in key areas of adolescent functioning are reviewed. Second, research on 3 constructs that are especially relevant to the investigation of within-gender individual differences in gender…

  1. Sexual behavior of adolescents

    Directory of Open Access Journals (Sweden)

    Mijatović-Jovanović Vesna

    2004-01-01

    Full Text Available Introduction Numerous studies have shown that sexual behavior increases among adolescents. Disharmony between biological and psychosocial maturity among young people may cause risky behavior, and endanger psychophysical and reproductive health of young persons. Material and methods A questionnaire on sexual behavior was completed by 169 adolescents, 1st and 4th year high school students. Results Every 6th first grade and every 2nd forth grade adolescent is sexually active. Male adolescents begin sexual activities significantly earlier (at the age of 15.6 than female adolescents (16.5. Also, young men have significantly more partners (3.6 than girls (1.3, and more parallel sexual relations than girls. Only 1/3 of sexually active adolescents always use some kind of contraception, more frequently boys (41.9% than girls (26.7%. Discussion Early commencement of sexual activity results with longer active period before realization of the reproductive function, which increases risk for reproductive health disorders. Unprotected sexual intercourse and large number of partners also present significant risk factors. Conclusion Sexual life of adolescents begins at the age of 16, on average, and only every third always uses contraceptive protection, which points to a need for better education on reproductive health by using contemporary methods. It is also necessary to increase availability of contraceptives (condoms at all places where adolescents spend time (in schools, bars, cinemas, disco clubs etc. in order to achieve responsible sexual behavior and protection of reproductive health among youth.

  2. Physical activity among adolescents

    DEFF Research Database (Denmark)

    Henriksen, P W; Ingholt, L; Rasmussen, M;

    2015-01-01

    The objectives of this study were (a) to examine the association between various kinds of parental social support and adolescents' physical activity (PA) and (b) to examine whether various kinds of social support from mothers and fathers were differently associated with boys' and girls' PA. Data...... understand why some adolescents are physically active and others are not....

  3. Adolescent Steroid Use.

    Science.gov (United States)

    Office of Inspector General (DHHS), Washington, DC.

    The study focused on non-medical steroid use by adolescents according to data obtained from the National Institute on Drug Abuse, professional literature, 30 key informants knowledgeable in steroid issues, and 72 current or former steroid users. The findings indicated: (1) over 250,000 adolescents, primarily males, used or have used steroids, and…

  4. Adolescence and Body Image.

    Science.gov (United States)

    Weinshenker, Naomi

    2002-01-01

    Discusses body image among adolescents, explaining that today's adolescents are more prone to body image distortions and dissatisfaction than ever and examining the historical context; how self-image develops; normative discontent; body image distortions; body dysmorphic disorder (BDD); vulnerability of boys (muscle dysmorphia); who is at risk;…

  5. Sexual Behavior in Adolescence

    Science.gov (United States)

    Hopkins, J. Roy

    1977-01-01

    Surveys conducted between the 1930's and 1970's on the sexual behavior of adolescents indicate the following: (1) older adolescents are more sexually experienced now than in earlier generations; (2) there has been a greater increase in incidence of premarital sex for females than males; and (3) there is a trend toward earlier sexual experience for…

  6. Adolescence Education Newsletter, 2001.

    Science.gov (United States)

    Villanueva, Carmelita L., Ed.; Espada-Carlos, Lichelle Dara, Ed.

    2001-01-01

    This document comprises the two 2001 issues of a UNESCO newsletter addressing topics related to adolescent well-being in the Asia-Pacific region, particularly reproductive and sexual health. Each issue contains news from the region on various initiatives related to adolescent health and education, as well as Web links and publications on the…

  7. Adolescence Education Newsletter, 2002.

    Science.gov (United States)

    Villanueva, Carmelita L., Ed.; Espada-Carlos, Lichelle Dara, Ed.

    2002-01-01

    This document consists of the two 2002 issues of a UNESCO newsletter addressing topics related to adolescent well-being in the Asia-Pacific region, particularly reproductive and sexual health. Each issue includes news from the region on various initiatives related to adolescent health and education, as well as Web links and publications on the…

  8. Rural female adolescence: Indian scenario.

    Science.gov (United States)

    Kumari, R

    1995-01-01

    This article describes the life conditions of female adolescents in India and issues such as health, discrimination in nutrition and literacy, child labor, early marriage, juvenile delinquency, and violence against girls in rural areas of India. Data are obtained from interview samples conducted among 12 villages in north India. Female adolescents suffer from a variety of poverty-ridden village life conditions: caste oppression, lack of facilities, malnutrition, educational backwardness, early marriage, domestic burden, and gender neglect. Girls carry a heavy work burden. Adolescence in rural areas is marked by the onset of puberty and the thrust into adulthood. Girls have no independent authority to control their sexuality or reproduction. Girls are expected to get married and produce children. Control of female sexuality is shifted from the father to the husband. There is a strong push to marry girls soon after menstruation, due to the burden of imposing strict restrictions on female sexuality, the desire to reduce the burden of financial support, and the need to ensure social security for daughters. Girls may not go out alone or stay outside after dark. Many rural parents fear that education and freedom would ruin their daughter. Girls develop a low self-image. Rural villages have poor sanitation, toilet facilities, and drainage systems. Girls are ignorant of health and sex education and lack access to education. The neglect of female children includes malnutrition, sex bias, and early marriage. In 1981, almost 4 out of every 100 girls had to work. 5.527 million girls 5-14 years old were child laborers. Girls are veiled, footbound, circumcised, and burnt by dowry hungry in-laws. Female delinquents are subjected to sexual harassment and sometime to sexual abuse while in custody. Cows are treated better in rural India than women. Gender disparity is caused by the perpetuation of patriarchal masculine values. PMID:12158005

  9. Breaks in Play: Do They Achieve Intended Aims?

    Science.gov (United States)

    Blaszczynski, Alexander; Cowley, Elizabeth; Anthony, Christina; Hinsley, Kate

    2016-06-01

    Breaks in play represent a responsible gambling strategy designed to disrupt states of dissociation and enhance the likelihood of drawing attention to a player's session behaviour and expenditure with respect to time and money. The aim of the break in play is to motivate the player to modify or cease gambling so the activity remains within affordable levels. The aim of this study was to investigate whether imposed breaks in play in the absence of accompanying warning messages were effective in reducing cravings. Participants (141 university students) were randomly allocated to one of three conditions: 15 min computer simulated Black Jack play followed by no break, a 3 or 8 min break in play. Participants were administered a battery of measures to assess problem gambling card play, cravings, and dissociation to assess the effects of length of break on cravings. Results indicated that cravings increased rather than decreased with imposed breaks in play, and that the strength of cravings were higher following the eight- compared to 3-min break. It was concluded that breaks in play in isolation might produce counterproductive, unintended, and even perverse effects. The policy implications for responsible gambling strategies is that breaks in play ought to be accompanied with warning and/or personal appraisal messages if optimal effects in reducing within session gambling expenditure are to be achieved. PMID:26275785

  10. Breakfast frequency among adolescents

    DEFF Research Database (Denmark)

    Pedersen, Trine Pagh; Holstein, Bjørn E; Damsgaard, Mogens Trab;

    2016-01-01

    OBJECTIVE: To investigate (i) associations between adolescents' frequency of breakfast and family functioning (close relations to parents, quality of family communication and family support) and (ii) if any observed associations between breakfast frequency and family functioning vary by...... (n 3054) from a random sample of forty-one schools. RESULTS: Nearly one-quarter of the adolescents had low breakfast frequency. Low breakfast frequency was associated with low family functioning measured by three dimensions. The OR (95 % CI) of low breakfast frequency was 1·81 (1·40, 2·33) for...... adolescents who reported no close relations to parents, 2·28 (1·61, 3·22) for adolescents who reported low level of quality of family communication and 2·09 (1·39, 3·15) for adolescents who reported low level of family support. Joint effect analyses suggested that the odds of low breakfast frequency among...

  11. Adolescent HIV treatment issues in South Africa.

    Science.gov (United States)

    Dawood, H

    2015-11-01

    Following the discovery of the human immunodeficiency virus (HIV), our knowledge of HIV infection and management has increased rapidly, but implementation of interventions has been slow in resource-limited settings. In particular, interventions such as antiretroviral treatment (ART) and prevention of mother-to-child transmission were hindered owing to lack of access to antiretroviral drugs. This resulted in ongoing HIV transmission, morbidity and mortality associated with opportunistic infections. Notwithstanding the current progress in HIV prevention and treatment, challenges remain in preventing new infections in adolescents and supporting and treating HIV-infected adolescents. Barriers to successful treatment of infection in adolescents include denial of diagnosis, poor understanding or perception of future benefits of treatment and current-orientated thinking that may contribute to non-adherence to ART. Side-effects that lead to stigmatisation, such as lipoatrophy (stavudine, zidovudine), diarrhoea and flatulence (lopinavir/ritonavir) and gynaecomastia (efavirenz), maybe intolerable and prevent adherence to treatment. This article highlights common treatment issues in HIV adolescent care and provides guidance on their management in the South African setting. PMID:26937511

  12. Friday on My Mind : The Relation of Partying With Antisocial Behavior of Early Adolescents. The TRAILS Study

    NARCIS (Netherlands)

    Veenstra, Rene; Huitsing, Gijs; Dijkstra, Jan; Lindenberg, Siegwart

    2010-01-01

    The relation between partying and antisocial behavior was investigated using a sample of Dutch early adolescents (T2: N=1,076; M age=13.52). Antisocial behavior was divided into rule-breaking and aggressive behavior. Using a goal-framing approach, it was argued that the relation of partying to antis

  13. Friday on My Mind: The Relation of Partying with Antisocial Behavior of Early Adolescents. The TRAILS Study

    Science.gov (United States)

    Veenstra, Rene; Huitsing, Gijs; Dijkstra, Jan Kornelis; Lindenberg, Siegwart

    2010-01-01

    The relation between partying and antisocial behavior was investigated using a sample of Dutch early adolescents (T2: N = 1,076; M age = 13.52). Antisocial behavior was divided into rule-breaking and aggressive behavior. Using a goal-framing approach, it was argued that the relation of partying to antisocial behavior depends on the way the need to…

  14. Multidimensional Family Therapy: Addressing Co-Occurring Substance Abuse and Other Problems among Adolescents with Comprehensive Family-Based Treatment

    OpenAIRE

    Rowe, Cynthia L.

    2010-01-01

    Adolescent substance abuse rarely occurs without other psychiatric and developmental problems, yet it is often treated and researched as if it can be isolated from comorbid conditions. Few comprehensive interventions are available that effectively address the range of co-occurring problems associated with adolescent substance abuse. This article reviews the clinical interventions and research evidence supporting the use of Multidimensional Family Therapy (MDFT) for adolescents with substance ...

  15. Semilocal string with Lorentz-breaking term

    International Nuclear Information System (INIS)

    Full text: Topological defects arising from the spontaneous symmetry breaking are physical systems of interest in a wide range of theories, from condensed matter to cosmology. These defects may arise from an abelian, as well as non-abelian, symmetry spontaneously broken. The type of the defect depends on the broken symmetry. Among the typical interesting defects are the vortex solutions, whose characteristics were extensively investigated in the literature. On the other hand,extensions of the standard model including Lorentz-violation terms have been greatly studied in recent years. It was demonstrated that a Maxwell-Higgs systems with a CPT-even Lorentz symmetry violating term yields Bogomolnyi-Prasad-Sommerfield (BPS) vortex solutions enjoying fractional quantization of the magnetic field. One of the benchmarks of the vortex theory is the semi local vortex. Usually, most part of the study of vortex was restricted to the local symmetry. However, the inclusion of a global symmetry, besides the usual local one, may lead to some interesting characteristics in the resulting topological defect as the presence of topological vortex even if the vacuum manifold is simply connected. This work is partially concerned with the demonstration that semi local vortices may be found in a usual Maxwell-Higgs system plus a CPT-even Lorentz symmetry violating term. In fact, starting from a SU(2) global x U(1) local symmetry, the symmetry breaks down to U(1) local. Hence, the first homotopy group is trivial, i. e., π1(SU(2)globalxU(1)local=U(1)local) = 1. However, the local symmetry also plays its role. Since the potential we shall deal with goes as usual, it is possible to say that as in the usual Higgs-Maxwell case , when no Lorentz-violating term is present, the arguments in favor of stable vortices are strong, but not exhaustive. In order to guarantee the existence of semi local vortices in the Maxwell-Higgs plus Lorentz-violating model, we have to construct the solutions. It was

  16. Breaking the cycle of dependency: dual diagnosis and AFDC families.

    Science.gov (United States)

    Bearman, D; Claydon, K; Kincheloe, J; Lodise, C

    1997-01-01

    This paper proposes that a comprehensive, long-term program with a case-management focus will produce better outcomes and be more cost-effective than the current approach to managing the illnesses of women on Temporary Assistance for Needy Families (or TANF, formerly known as AFDC) who are afflicted with both drug dependency and mental illness, i.e. a dual diagnosis. It is proposed that this comprehensive approach would diminish the generational cycle of substance abuse, dysfunction (including violence), and dependence on public support, which is too often the pattern in single-parent homes where the mother has been dually diagnosed. For our purposes, dual diagnosis is defined as any mental health diagnosis using the DSM-IV criteria coexisting with a diagnosis of substance abuse, whether licit or illicit. Current drug policy, particularly as it applies to those with a dual diagnosis, has an emphasis on criminal justice system solutions. It is extremely expensive (incarceration alone is variously estimated as costing $25,000 to $45,000 per year per person), and does little to treat, prevent, or consequently, reduce the problem. The model design discussed in this article provides for comprehensive treatment and support services to women with a dual diagnosis receiving TANF. Its goal is to help break the family cycle of system dependency. The article hypothesizes that if a well-designed program evaluation is implemented, it will demonstrate savings in reduced health care, criminal justice, and social service costs. PMID:9460030

  17. Peer Effects in Adolescent Cannabis Use: It's the Friends, Stupid

    OpenAIRE

    John Moriarty; Duncan McVicar; Kathryn Higgins

    2012-01-01

    This paper examines peer effects in adolescent cannabis use from several different reference groups, exploiting survey data that have many desirable properties and have not previously been used for this purpose. Treating the school grade as the reference group, and using both neighbourhood fixed effects and IV for identification, we find evidence of large, positive, and statistically significant peer effects. Treating nominated friends as the reference group, and using both school fixed effec...

  18. Psychiatric treatments for children and adolescents preferred by spanish psychiatrists

    OpenAIRE

    Josep Toro; María Mur; Tomás Cantó

    2006-01-01

    Objectives: To study the prescription criteria of Spanish psychiatrists treating children and adolescents. Methods: a survey was designed to record their first choice and complementary preferences for pharmacological, psychotherapeutic and psychoeducational interventions in five disorders: autism, depression, separation anxiety, obsessive compulsive and attention-deficit/hyperactivity disorders. Results: One hundred and nine psychiatrists responded. No distinction was made between children an...

  19. Serious Emotional Disturbance in Children and Adolescents: Multisystemic Therapy.

    Science.gov (United States)

    Henggeler, Scott W.; Schoenwald, Sonja K.; Rowland, Melisa D.; Cunningham, Phillippe B.

    Originally developed to treat antisocial behavior, multisystemic therapy (MST) has emerged as a leading evidence-based treatment for serious emotional disturbance in children and adolescents. This manual presents the MST approach to working with this challenging population. Delineated are ways to develop and implement collaborative interventions…

  20. Child and Adolescent Therapy: Cognitive-Behavioral Procedures. Fourth Edition

    Science.gov (United States)

    Kendall, Philip C., Ed.

    2011-01-01

    Widely regarded as the definitive clinical reference and text in the field, this authoritative volume presents effective cognitive-behavioral approaches for treating frequently encountered child and adolescent disorders. The editor and contributors are leading experts who provide hands-on, how-to-do-it descriptions illustrated with clinical…