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Sample records for brasil-argentina agencia contabil controle mater nuclear

  1. A integração bilateral Brasil-Argentina: tecnologia nuclear e Mercosul

    Directory of Open Access Journals (Sweden)

    Odete Maria de Oliveira

    1998-06-01

    Full Text Available O presente trabalho focaliza o complexo processo de integração bilateral Brasil-Argentina, iniciado formalmente na década de 80, desdobrado em sua dupla abrangência: a cooperação pacífica da tecnologia nuclear; b constituição de um mercado comum. A evolução desse processo conduziu-se através de ciclos fundamentais: primeira etapa, antecedentes de aproximação; segunda etapa, os decisivos instrumentos da ampla integração; terceira etapa, solidificação de duas bases, uma de nível tecnológico nuclear, pactuando um sistema sui generis de salvaguardas e a vigência do Tratado de Tlatelolco (emendado, e, outra, de nível econômico pelo Tratado de Assunção, instituindo o Mercosul.The present work focuses on the complex bilateral integration process involving Brazil and Argentina that began formally during the 80's, and displayed in its double scope: a pacific cooperation on nuclear technology; b constitution of a common market. This process evolution took place in three fundamental circles: the first one, approximation antecedents; the second one, decisive instruments for a large integration; and the third one, the solidification of two basis, one at the nuclear technological level, joining the two countries in the sui generis back up system and the operation of the Tlatelolco Treaty, the other, at the economic level instituting the Mercosur by the Asunción Treaty.

  2. A integração bilateral Brasil-Argentina: tecnologia nuclear e Mercosul

    National Research Council Canada - National Science Library

    Odete Maria de Oliveira

    1998-01-01

    ...; and the third one, the solidification of two basis, one at the nuclear technological level, joining the two countries in the sui generis back up system and the operation of the Tlatelolco Treaty, the...

  3. ABACC - Brazil-Argentina Agency for Accounting and Control of Nuclear Materials, a model of integration and transparence; ABACC - Agencia Brasileno-Argentina de Contabilidad y Control de Materiales Nucleares, un ejemplo de integracion y transparencia

    Energy Technology Data Exchange (ETDEWEB)

    Oliveira, Antonio A.; Do Canto, Odilon Marcusso, E-mail: oliveira@abacc.org.br, E-mail: odilon@abacc.org.br [Agencia Brasileno Argentina de Contabilidad y Control de Materiales Nucleares (ABACC), Rio de Janeiro, RJ (Brazil)

    2013-07-01

    Argentina and Brazil began its activities in the nuclear area about the same time, in the 50 century past. The existence of an international nuclear nonproliferation treaty-TNP-seen by Brazil and Argentina as discriminatory and prejudicial to the interests of the countries without nuclear weapons, led to the need for a common system of control of nuclear material between the two countries to somehow provide assurances to the international community of the exclusively peaceful purpose of its nuclear programs. The creation of a common system, assured the establishment of uniform procedures to implement safeguards in Argentina and Brazil, so the same requirements and safeguards procedures took effect in both countries, and the operators of nuclear facilities began to follow the same rules of control of nuclear materials and subjected to the same type of verification and control. On July 18, 1991, the Bilateral Agreement for the Exclusively Peaceful Use of Nuclear Energy created a binational body, the Argentina-Brazil Agency for Accounting and Control of Nuclear Materials-ABACC-to implement the so-called Common System of Accounting and Control of Nuclear materials - SCCC. The deal provided, permanently, a clear commitment to use exclusively for peaceful purposes all material and nuclear facilities under the jurisdiction or control of the two countries. The Quadripartite Agreement, signed in December of that year, between the two countries, ABACC and IAEA completed the legal framework for the implementation of comprehensive safeguards system. The 'model ABACC' now represents a paradigmatic framework in the long process of economic, political, technological and cultural integration of the two countries. Argentina and Brazil were able to establish a guarantee system that is unique in the world today and that consolidated and matured over more than twenty years, has earned the respect of the international community.

  4. Átomos na integração: a aproximação Brasil-Argentina no campo nuclear e a construção do Mercosul

    Directory of Open Access Journals (Sweden)

    Everton Vieira Vargas

    1997-06-01

    Full Text Available Este trabalho tenciona ser uma reflexão sobre a importância da aproximação entre o Brasil e a Argentina no campo nuclear, na segunda metade da década de 80 e no início dos anos 90, como fundamento para a construção de um relacionamento novo que suplantou uma rivalidade histórica entre ambos. O processo de aproximação encetado com um propósito aparentemente econômico, tinha uma dimensão estratégica. As repercussões desse esforço iam além dos interesses bilaterais imediatos e se refletiram na busca de uma nova inserção internacional dos dois países, num momento de transformações profundas nos planos interno e internacional. Através do programa de integração Brasil-Argentina (que mais tarde também envolveu o Uruguai e do MERCOSUL buscou-se estabelecer uma arquitetura político-jurídica, que criou uma realidade que extrapola o campo econômico e projeta-se no terreno político.This paper aims to be a reflection on the importance of the Brazil and Argentina closer relations in the nuclear field, in the late eighties and early nineties, as the basis for building a new relationship that replaced a historical rivalry. The aproximation process has begun with apparently economic purposes, but also had a strategic dimension. The repercussions of this effort went beyond immediate bilateral interests, reflected in the search for a new international insertion by both countries, at a time of deep transformations, both internally and internationally. The Brazil-Argentina integration program (that later also involved Uruguay and MERCOSUL led to the establishment of a political-legal structure that created a reality that goes beyond economics to the political domain.

  5. The Nuclear and Safety Council and the Nuclear Energy Agency; El Consejo de Seguridad Nuclear y la Agencia de Energia Nuclear. Una estrecha colaboracion

    Energy Technology Data Exchange (ETDEWEB)

    Martinez Ten, C.

    2008-07-01

    On the occasion of the fiftieth anniversary of creation of the Nuclear Energy Agency (NEA), specialised agency within the Organisation for Economic Cooperation and Development (OECD), the President of the Spanish Nuclear Safety Council (CSN), summarizes the activities of the NEA throughout its life up to now. Since it started up, the CSN has worked closely with this international organization, as a reflection of the strong commitment, shared by both institutions, each one in its field, to reach the highest levels in the regulation which contributes decisively to the nuclear safety of the Spanish nuclear power plants. (Author)

  6. The accountability of the brazilian regulatory agencies: the experience of the National Petroleum Agency; O controle externo das agencias reguladoras: o caso da Agencia Nacional do Petroleo

    Energy Technology Data Exchange (ETDEWEB)

    Pinto Junior, Helder Queiroz; Borges, Heloisa Lopes [Universidade Federal do Rio de Janeiro (UFRJ), RJ (Brazil). Inst. de Economia. Grupo de Economia da Energia

    2004-07-01

    During the reform process for which passed the Brazilian Oil and Gas Industry, the academic debate was centered mostly in the sectorial restructuring process, in the contract designs and regulatory environment for the industries in change, particularly the desired attributes of its institutions. The debate tends, in the present, to converge towards the existence of different possible combinations between market structures and institutional structures (the regulators among them) that would lead to a desirable result. Thus, the various characteristics and configurations, originally appointed as necessary conditions for the success of any reform, are not dealt with such great deference anymore. The hypothesis that the existence of a independent regulator is a determinant choice for the success of structural and institutional reforms was relaxed as general rule, but there are still strong economic reasons to justify the option, adopted in Brazil. The creation of the Oil National Agency (ANP), the Brazilian regulator for the Oil and Gas Industry is a recent phenomenon. And few studies specifically approach the issue of its accountability, institutional role that in Brazil is delegated mostly, but not exclusively, to the National Court of Accounts (Tribunal de Contas da Uniao). Therefore, the objective of this work will be to discuss the different possibilities of accountability over the ANP, evaluating the paper and the functions of the TCU and the forms of external control on the Agency, pointing out the possibilities, the impediments and the challenges, as well as the economic consequences to the Natural Gas Industry of the current configuration. (author)

  7. La comunicación interna y los conflictos laborales internos de la Agencia de Regulación y Control de Electricidad - ARCONEL

    OpenAIRE

    Ramos Ulloa, Andrés Camilo

    2016-01-01

    En la actualidad el éxito de toda empresa o institución se fundamenta en la comunicación interna ya que su propósito es llevar a cabo el cambio por ende el desarrollo empresarial. El objetivo del presente trabajo de investigación es establecer y definir parámetros que permitan mejorar las relaciones laborales en la Agencia de Control y Regulación de Electricidad ARCONEL, a fin de potencializar todos los recursos e influir sobre la acción en beneficio de la institución. Se inicia con una descr...

  8. MaterSci

    CERN Document Server

    MaterSci.Net provides a searchable database of Internet resources related to Materials Science and Metallurgy. Launched in January of 2000, the mission of MaterSci.Net is to become the best source for information related to all branches of Materials. This includes consideration of materials and components as used therein, standardization of definitions, nomenclature, symbols, and operating characteristics; and exchange of information as by techn. papers, conference sessions, and demonstrations

  9. The Nuclear Energy Agency of the OECD through its history; La Agencia de Energia Nuclear de la OCDE, a traves de su historia

    Energy Technology Data Exchange (ETDEWEB)

    Echavarri, L.

    2008-07-01

    This year, 2008, marks the 50th Anniversary of the OECD Nuclear Energy Agency (NEA). During these years the Agency has adapted to the evolution of the world energy situation. At the beginning the Agency launches international collaboration projects to establish the technological bases required for nuclear energy, then helps member countries in the construction of nuclear power plants and later analyzes the safety criteria as a consequence of the Three Miles Island and Chernobyl accidents. Based on this experience, the NEA faces the X XI Century prepared to contribute, even more, to a better international collaboration for a safe, environmentally friendly and economical use of the nuclear energy. (Author)

  10. NUCLEAR REACTOR CONTROL SYSTEM

    Science.gov (United States)

    Epler, E.P.; Hanauer, S.H.; Oakes, L.C.

    1959-11-01

    A control system is described for a nuclear reactor using enriched uranium fuel of the type of the swimming pool and other heterogeneous nuclear reactors. Circuits are included for automatically removing and inserting the control rods during the course of normal operation. Appropriate safety circuits close down the nuclear reactor in the event of emergency.

  11. IMPACTUL DATELOR CONTABILE ÎN PRACTICA FISCALĂ

    Directory of Open Access Journals (Sweden)

    Maia BAJAN

    2015-12-01

    Full Text Available Popularitatea dezbaterilor privind relaţiile dintre contabilitate şi fiscalitate a căpătat noi dimensiuni în contextul glo­balizării, deschiderii pieţelor şi necesităţii de racordare la anumite cadre. Întrucât fiscalitatea şi contabilitatea sunt două ştiinţe independente una de cealaltă, activitatea economico-financiară a entităţilor, instituţiilor de stat sau altor regii autonome este într-un final reflectată în documentele contabile şi în cele fiscale. În acest context, este necesar ca ele să fie analizate în ansamblu. Totuşi, dintotdeauna a existat problema concilierii celor două domenii, geneza acesteia fiind diferenţele dintre principiile contabile şi cele fiscale privind evaluarea şi calculul economic. Acestea din urmă urmăresc stimularea sau inhibarea unor activităţi; respectiv, este de înţeles că principiile fiscale nu vor prezenta mereu imaginea fidelă a operaţiilor ce au loc în cadrul entităţii. THE IMPACT OF ACCOUNTING INFORMATION ON TAX PURPOSESThe degree of awareness towards the relationships between accounting and taxation has reached as new level in the context of the actual deep globalization process, the open markets and the need for connection to certain frames. Given that accountancy and taxation are two independent sciences, the economic activity of entities, state institutions or other autonomous administrative bodies is in the end reflected both in accounting and tax documents. Therefore, it is necessary to analyze them as a whole. Nonetheless, there has always existed the issue of conciliating the two domains, because of the differences among accounting and tax principles for evaluation and economic calculation. Tax principles are generally set as to stimulate or inhibit certain activities. It is obvious that they will not always reflect the true and fair view of the operations taking place within the entity. 

  12. Stabat Mater. Chant gregorien / Patric Wiklacz

    Index Scriptorium Estoniae

    Wiklacz, Patric

    1997-01-01

    Uuest heliplaadist "Stabat Mater. Chant gregorien. Palestrina: Stabat Mater a 8; Pärt: Stabat Mater; Browne: Stabat Mater dolorosa a 6. Fretwork (concort de violes)". Virgin Classics 545 272-2 (CD: 167F)

  13. Colombia, Brasil, Argentina y Chilepráctica educativa y orientaciones pedagógicas

    Directory of Open Access Journals (Sweden)

    Carlos Federico Ayala Zuluaga

    2017-01-01

    Full Text Available El presente artículo discute aspectos de la Práctica Educativa en cuatro universidades oficiales, o del estado, en: Colombia, Brasil, Argentina, y Chile y está en relación con las orientaciones pedagógicas propuestas por Feiman (1990 e Imbernon (2007. El enfoque de la investigación es cualitativo y busca comprender aspectos intrínsecos, regionales, culturales, y políticos de la práctica educativa relacionada con orientaciones pedagógicas, mediante un proceso de preanálisis fluctuante de la información, la codificación e identificación de categorías, y finalmente la descripción, categorización, inferencia e interpretación de la información recogida. En los resultados se evidencia que las orientaciones pedagógicas convergen en la acción, la reflexión, el conocimiento, el uso de las Tecnologías digitales de información y comunicación, y en el desarrollo de la identidad docente. Conclusiones principales: las orientaciones pedagógicas predominantes en la práctica educativa oficial son la académica y la tecnicista, y en las universidades son la tradicional, académica, de eficacia social, hermenéutica y la centrada en procesos.

  14. Invasive vertebrate species in Chile and their control and monitoring by governmental agencies Especies de vertebrados invasores en Chile y su control y monitoreo por agencias gubernamentales

    Directory of Open Access Journals (Sweden)

    J. AGUSTÍN IRIARTE

    2005-03-01

    Full Text Available We provide an overview of the current status of vertebrate invasive species throughout Chile, updating information on terrestrial exotics and reporting for the first time the situation of exotic freshwater fishes. In addition, we document the legislation and programs that the Chilean government has implemented to limit the entry of exotics to the country or minimize their impact on native wild flora and fauna and on natural ecosystems. We document what is known about the introduction of 26 exotic fish species to continental waters of the country, discussing the distribution and putative effects of those 11 species that may be considered invasive. From a previous list of 24 terrestrial vertebrate invaders, we withdraw the Argentine tortoise (Chelonoidis chilensis, reindeer (Rangifer tarandus and mouflon (Ovis ammon because there are no data on their subsistence in the wild. On the other hand, we add three new species: red-eared freshwater turtle (Trachemys scripta, monk parakeet (Myiopsitta monachus, and red-crested cardinal (Paroaria coronata, thus keeping the total number of terrestrial invaders unchanged at 24 species. The chief agency in charge of existing laws and regulations regarding the import of exotic freshwater species is the National Fisheries Service (SERNAPESCA, in Spanish, a dependency of the Ministry of Economy. The main agency in charge of enforcing existing laws and regulations regarding the import of exotic terrestrial species to Chile is the Agriculture and Livestock Service (SAG, in Spanish, a dependency of the Ministry of Agriculture. Currently, SAG is not only controlling major border passes, seaports and airports, but also is funding studies to monitor and control already existing invaders. In addition, the Chilean Forest Service (CONAF, in Spanish is also concerned about invasive species, but only if they enter national parks and reserves within the National System of Protected Wildlife Areas (SNASPE, in Spanish

  15. Nuclear energy Agency (NEA) of OECD: 50 years of contributions to nuclear safety; La Agencia de Energia Nuclear (NEA) de la OCDE: 50 anos de contribucion a la seguridad nuclear

    Energy Technology Data Exchange (ETDEWEB)

    Reig, J.

    2009-07-01

    The article describes the evolution of the OECD Nuclear Energy Agency (NEA) from its inception to today, when they have just commemorated its 50th anniversary. The Agency's contribution in the fields of nuclear safety, regulation, radiation protection and waste management are presented. The article refers to the impact in the Agency's activities of the two accidents occurred in Chernobyl and three Mile Island, as well as the influence of the moratorium at the end of the 80's and the renaissance happening these past years. Special emphasis is given to two key programmes of the Agency, like the Multinational Design Evaluation Programme (MDEP) and the Generation IV Forum (GIF). The conclusion presents the Agency decision to continue contribute contributing to the use of nuclear energy in a safe, economic and environmentally friendly manner. (Author)

  16. Gestor de reservas para una agencia de viaje

    OpenAIRE

    Vilela Atachao, Judith

    2013-01-01

    Vivimos en una sociedad donde necesitamos simplificar y agilizar las gestiones laborales de pequeñas y medianas empresas, informatizando estas tareas ofrecerán más servicios y de mejor calidad a sus clientes. Con esta línea de pensamiento surge la creación de este proyecto, gestor de reservas para una agencia de viajes “Manabí”. Debido al gran volumen de trabajo que experimentan empresas como la de una agencia de viajes y el hecho de que quieran llevar un control de su gesti...

  17. Nuclear reactor control column

    Science.gov (United States)

    Bachovchin, Dennis M.

    1982-01-01

    The nuclear reactor control column comprises a column disposed within the nuclear reactor core having a variable cross-section hollow channel and containing balls whose vertical location is determined by the flow of the reactor coolant through the column. The control column is divided into three basic sections wherein each of the sections has a different cross-sectional area. The uppermost section of the control column has the greatest cross-sectional area, the intermediate section of the control column has the smallest cross-sectional area, and the lowermost section of the control column has the intermediate cross-sectional area. In this manner, the area of the uppermost section can be established such that when the reactor coolant is flowing under normal conditions therethrough, the absorber balls will be lifted and suspended in a fluidized bed manner in the upper section. However, when the reactor coolant flow falls below a predetermined value, the absorber balls will fall through the intermediate section and into the lowermost section, thereby reducing the reactivity of the reactor core and shutting down the reactor.

  18. Própolis produzida no sul do Brasil, Argentina e Uruguai: evidências fitoquímicas de sua origem vegetal

    Directory of Open Access Journals (Sweden)

    Park Yong Kun

    2002-01-01

    Full Text Available A própolis é uma substância resinosa coletada pelas abelhas de diversas partes da planta. Sua composição depende da época, vegetação e área de coleta. Própolis produzida por abelhas Apis mellifera africanizada do sul do Brasil, Argentina e Uruguai foram investigadas por meio de técnicas cromatográficas. De acordo com os resultados obtidos por CCDAE-FR, CLAE-FR e CG-EM, as própolis do sul do Brasil foram classificadas em 5 grupos distintos. Com base nas evidências fitoquímicas, Populus alba foi identificada como a principal fonte da própolis do grupo 3 do sul do Brasil, Argentina e Uruguai.

  19. El contrato de agencia comercial

    Directory of Open Access Journals (Sweden)

    María Elisa Camacho López

    2008-12-01

    Full Text Available Uno de los compromisos asumidos por el Gobierno de la República de Colombia en el Tratado de Libre Comercio celebrado con el Gobierno de los Estados Unidos, cuyo texto aún no ha entrado en vigor, consiste en la eliminación o modificación de algunos de los elementos que regulan el contrato de Agencia Comercial, los cuales, a su vez, valga la pena resaltar, nunca han gozado de una pacífica comprensión. Razón por la cual, aprovechando ambas circunstancias, hemos querido analizar el proceso de tipificación de este contrato a nivel global, desde sus inicios hasta sus más recientes desarrollos, con el objeto de determinar la conveniencia de los cambios solicitados.

  20. Problema de la agencia y la cultura corporativa estalinista

    Directory of Open Access Journals (Sweden)

    Yurí Gorbaneff

    2004-12-01

    Full Text Available El problema de la agencia es de los obstáculos para la eficiencia de las organizaciones. A partir de Alchian y Demsetz (1972.la teoría sugiere dos soluciones: la propiedad privada y la cultura corporativa. Sin embargo, aislar el efecto de la cultura sobre las organizaciones no es fácil. La "ingeniería social" estalinista ofrece un material interesante para evaluar los efectos de la cultura corporativa sobre el sistema económico. Acá se sostiene la hipótesis de que los dirigentes soviéticos, al enfrentar los crecientes costos de la agencia tuvieron que inventar otra método, que no fuera la propiedad privada ni el control democrático directo sobre el aparato productivo, para controlar la pérdida de la agencia. Ellos recurrieron a la implantación de la cultura corporativa heroica a nivel nacional. Este trabajo muestra que la propaganda política, el arte, la literatura, los movimientos populares y el culto a la personalidad de Stalin fueran las herramientas gerenciales clave para implantar la cultura corporativa heroica, indispensable en la economía planificada. Su aplicación fue exitosa y generó las condiciones necesarias para la industrialización entre 1920 y 1930 y para el alto desempeño de la economía soviética durante la Segunda Guerra Mundial. La segunda hipótesis consiste en que el fantasma de la agencia, ahuyentado entre 1920 y 1950 por la cultura heroica estalinista, terminó devorando la economía planificada.

  1. Controlled Nuclear Fusion.

    Science.gov (United States)

    Glasstone, Samuel

    This publication is one of a series of information booklets for the general public published by The United States Atomic Energy Commission. Among the topics discussed are: Importance of Fusion Energy; Conditions for Nuclear Fusion; Thermonuclear Reactions in Plasmas; Plasma Confinement by Magnetic Fields; Experiments With Plasmas; High-Temperature…

  2. Nuclear physicist, arms control advocate

    CERN Multimedia

    Chang, K

    2002-01-01

    Victor F. Weisskopf, a nuclear physicist who worked on the Manhattan Project to build the first atomic bomb in World War II and later became an ardent advocate of arms control, died Monday at his home in Newton, MA, USA. He was 93 (1 page).

  3. Análise do sistema de normalização contabilística da Polónia

    OpenAIRE

    Silva, Ana Margarida Pinto

    2009-01-01

    A Lei da Contabilidade (“Ustawa o Rachunkowosci”), aprovada pelo Parlamento Polaco em 29 de Setembro de 1994, constituiu um passo significativo na incorporação das normas de Contabilidade ocidentais. De acordo com UNCTD (2008), essa lei define os mais importantes e fundamentais conceitos contabilísticos, tornando as demonstrações financeiras polacas comparáveis e proporcionando uma maior transparência nas operações económicas na Polónia. Desde o início da reforma da Contabil...

  4. Whither the legal control of nuclear energy?

    Energy Technology Data Exchange (ETDEWEB)

    Riley, Peter [Leicester School of Law (United Kingdom). Environmental Law Unit

    1995-12-31

    International nuclear trade is governed by the regime of legal control of nuclear energy, nuclear materials, knowledge of nuclear processes and weapons. Nuclear trade is under pinned by international agreements concerning physical protection and safeguards, the control of nuclear weapons, the protection of nuclear materials from terrorist action and third part liability. The political and geographical boundary changes of the past two years have significantly altered the background against which this regime has developed. Such changes have affected nuclear trade. The paper summarised the legal control of nuclear energy between States, identifies the areas of change which may affect this regime and the consequences for international trade. Conclusions are drawn as to the development of the international legal control of nuclear energy. (author). 21 refs.

  5. Intercomparison of activity measures of 1 {sup 31}I, {sup 67}Ga and {sup 201}Tl in nuclear medicine services in Recife/PE; Intercomparacao de medidas de atividade de {sup 131}I, {sup 67}Ga e {sup 201}Tl em servicos de medicina nuclear do Recife/PE

    Energy Technology Data Exchange (ETDEWEB)

    Couto, Iris Tairini V. do, E-mail: iristairini@hotmail.com [Instituto Federal de Educacao, Ciencia e Tecnologia de Pernambuco (IFPE), Recife, PE (Brazil); Fragoso, Maria da Conceicao de F.; Oliveira, Mercia Liane de, E-mail: mercial@cnen.gov.br [Centro Regional de Ciencias Nucleares do Nordeste (CRCN-NE/CNEN-PE), Recife, PE (Brazil)

    2013-07-01

    In this work, we intend to evaluate the performance of radionuclide calibrators of the Nuclear Medicine Services of the Recife (Brazil), the measurement procedures used by the professionals of these services and the frequency of the application of quality control testing required by Comissao Nacional de Energia Nuclear (CNEN) and the Agencia Nacional de Vigilancia Sanitaria (ANVISA), performing an intercomparison of radionuclides measurements.

  6. Comparative evaluation of guided tissue regeneration with use of collagen-based barrier freeze-dried dura mater allograft for mandibular class 2 furcation defects (a comparative controlled clinical study).

    Science.gov (United States)

    Patel, Sandeep; Kubavat, Ajay; Ruparelia, Brijesh; Agarwal, Arvind; Panda, Anup

    2012-01-01

    The aim of periodontal surgery is complete regeneration. The present study was designed to evaluate and compare clinically soft tissue changes in form of probing pocket depth, gingival shrinkage, attachment level and hard tissue changes in form of horizontal and vertical bone level using resorbable membranes. Twelve subjects with bilateral class 2 furcation defects were selected. After initial phase one treatment, open debridement was performed in control site while freezedried dura mater allograft was used in experimental site. Soft and hard tissue parameters were registered intrasurgically. Nine months reentry ensured better understanding and evaluation of the final outcome of the study. Guided tissue regeneration is a predictable treatment modality for class 2 furcation defect. There was statistically significant reduction in pocket depth as compared to control (p tissue parameter, significant defect fill resulted in experimental group, while in control group, less significant defect fill was found in horizontal direction and nonsignificant defect fill was found in vertical direction. The results showed statistically significant improvement in soft and hard tissue parameters and less gingival shrinkage in experimental sites compared to control site. The use of FDDMA in furcation defects helps us to achieve predictable results. This cross-linked collagen membrane has better handling properties and ease of procurement as well as economic viability making it a logical material to be used in regenerative surgeries.

  7. Nuclear reactor kinetics and plant control

    CERN Document Server

    Oka, Yoshiaki

    2013-01-01

    Understanding time-dependent behaviors of nuclear reactors and the methods of their control is essential to the operation and safety of nuclear power plants. This book provides graduate students, researchers, and engineers in nuclear engineering comprehensive information on both the fundamental theory of nuclear reactor kinetics and control and the state-of-the-art practice in actual plants, as well as the idea of how to bridge the two. The first part focuses on understanding fundamental nuclear kinetics. It introduces delayed neutrons, fission chain reactions, point kinetics theory, reactivit

  8. Autonomous Control of Space Nuclear Reactors Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Nuclear reactors to support future robotic and manned missions impose new and innovative technological requirements for their control and protection instrumentation....

  9. Reactivity control assembly for nuclear reactor

    Science.gov (United States)

    Bollinger, Lawrence R.

    1984-01-01

    Reactivity control assembly for nuclear reactor comprises supports stacked above reactor core for holding control rods. Couplers associated with the supports and a vertically movable drive shaft have lugs at their lower ends for engagement with the supports.

  10. Relações Brasil-Argentina: a cooperação cultural como instrumento de integração regional

    Directory of Open Access Journals (Sweden)

    Raquel Paz dos Santos

    2009-12-01

    Full Text Available Este estudo desenvolve uma nova perspectiva das relações Brasil-Argentina a partir da análise de sua dimensão cultural entre os anos 1930-1954. Trata-se de mostrar como uma aproximação entre esses dois países foi incentivada através de projetos de cooperação intelectual, científica e artística, com o objetivo de desfazer imagens negativas e criar um sentimento de fraternidade entre brasileiros e argentinos. Com base na ideia de que uma maior cooperação contribuiria para o fortalecimento da região, e com o objetivo de alcançar uma futura integração econômica, essa prática também foi estimulada entre os demais países da América do Sul.

  11. 77 FR 28407 - Special Nuclear Material Control and Accounting Systems for Nuclear Power Plants

    Science.gov (United States)

    2012-05-14

    ... COMMISSION Special Nuclear Material Control and Accounting Systems for Nuclear Power Plants AGENCY: Nuclear...-5028, ``Special Nuclear Material Control and Accounting Systems for Nuclear Power Plants.'' In DG-5028... Control and Accounting Systems for Nuclear Power Plants.'' DATES: Submit comments by July 16, 2012...

  12. Plan de empresa. Agencia de marketing y publicidad.

    OpenAIRE

    NAVARRO TARAZONA, ALEJANDRO

    2015-01-01

    [ES] Se analiza la puesta en marcha de un modelo de negocio consistente en una agencia que ofrece servicios de marketing integrales y/o puntuales, con el principal objetivo de darse a conocer y ofrecer sus servicios a todas aquellas empresas que necesitan dicho servicio para satisfacer sus necesidades y convertirse en una empresa de referencia en el sector, mediante un trabajo eficaz y rentable. Navarro Tarazona, A. (2015). Plan de empresa. Agencia de marketing y publicidad....

  13. Nuclear electric propulsion reactor control systems status

    Science.gov (United States)

    Ferg, D. A.

    1973-01-01

    The thermionic reactor control system design studies conducted over the past several years for a nuclear electric propulsion system are described and summarized. The relevant reactor control system studies are discussed in qualitative terms, pointing out the significant advantages and disadvantages including the impact that the various control systems would have on the nuclear electric propulsion system design. A recommendation for the reference control system is made, and a program for future work leading to an engineering model is described.

  14. 78 FR 38739 - Special Nuclear Material Control and Accounting Systems for Nuclear Power Plants

    Science.gov (United States)

    2013-06-27

    ... COMMISSION Special Nuclear Material Control and Accounting Systems for Nuclear Power Plants AGENCY: Nuclear... Accounting Systems for Nuclear Power Plants.'' This regulatory guide provides guidance on recordkeeping and... nuclear material control and accounting system requirements for nuclear power plants. This guide applies...

  15. Autonomous Control of Space Nuclear Reactors Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Nuclear reactors to support future lunar and Mars robotic and manned missions impose new and innovative technological requirements for their control and protection...

  16. Alteraçoes das práticas contabilísticas na Casa da Moeda de Lisboa no século XVIII = Changes in accounting practices at the Lisbon Mint in the 18th century

    Directory of Open Access Journals (Sweden)

    Rita Martins De Sousa

    2011-12-01

    Full Text Available En este artículo se explica el cambio de prácticas contables en la Casa da Moeda de Lisboa encuadrándolas en la política de difusión de la contabilidad por partida doble en el ámbito público en Portugal durante la segunda mitad del siglo XVIII.La necesidad del Estado de ejercer un mayor control sobre sus fuentes de ingresos justificó la transformación ocurrida demostrando la adaptación de las prácticas contables a las características de cada organización. En la Casa da Moeda, lo específico de su misión acuñación de monedas originó una legislación propia fechada en 1773. La periodización de estas prácticas contables en la Casa da Moeda de Lisboa se organizó en tres fases: la primera entre 1686 y 1761, la segunda entre 1761 y 1773 y por último desde 1773 a 1797, período final de este estudio.This article explains the changes made to accounting practices at the Lisbon Mint within the context of the introduction of double-entry bookkeeping into the public sphere in Portugal during the second half of the 18th century.The State’s requirement to exercise greater control over its sources of income justified the changes that took place, with accounting practices being adapted to the features of each organisation. The Mint's specific function –the minting of metallic money– gave rise to the creation of its own particular legislation, in 1773. The study of these accounting practices at the Lisbon Mint will be divided into three separate periods: firstly from 1686 to 1761, secondly from 1761 to 1773, and finally from 1773 to 1797. Neste artigo explica-se a alteração das práticas contabilísticas na Casa da Moeda de Lisboa enquadrando-as na política de difusão da contabilidade por partidas dobradas na esfera pública, em Portugal, na segunda metade do século XVIII.A necessidade de um maior controlo exercido pelo Estado sobre as suas fontes de receita justificarão as transformações ocorridas, demonstrando estas a

  17. Development and evaluation of Standard Operating Procedures (SOPs) for quality control tests and radiological protection activities in a Nuclear Medicine Service

    Energy Technology Data Exchange (ETDEWEB)

    Krempser, Alexandre R., E-mail: krempser@peb.ufrj.br [Universidade Federal do Rio de Janeiro (PEB/COPPE/UFRJ), RJ (Brazil). Programa de Engenharia Biomedica; Soares, Alexandre B. [Universidade Federal do Rio de Janeiro (IF/UFRJ), Rio de Janeiro, RJ (Brazil). Inst. de Fisica; Corbo, Rossana [Universidade Federal do Rio de Janeiro (FM/UFRJ), Rio de Janeiro, RJ (Brazil). Dept. de Radiologia

    2011-07-01

    The quality management in Nuclear Medicine Services is a requirement of national and international standards. The Brazilian regulatory agency in health surveillance, the Agencia Nacional de Vigilancia Sanitaria (ANVISA), in its Resolucao de Diretoria Colegiada (Collegiate Directory Resolution) no. 38, requires the elaboration of documents describing the technical and clinical routine activities. This study aimed to elaborate, implement and evaluate Standard Operating Procedures (SOPs) for quality control tests and radiological protection activities in the Nuclear Medicine Service of a university hospital. Eighteen SOPs were developed, involving tasks related to dose calibrator, gamma camera, Geiger-Muller detectors and radiological protection activities. The performance of its application was evaluated for a period of six months. It was observed a reduction in 75% of reported operational errors and 42% of the number of reported incidents with contamination by radioactive material. The SOPs were adequate and successful in its application. New procedures involving clinical activities will also be developed and evaluated. (author)

  18. Autonomous Control of Nuclear Power Plants

    Energy Technology Data Exchange (ETDEWEB)

    Basher, H.

    2003-10-20

    A nuclear reactor is a complex system that requires highly sophisticated controllers to ensure that desired performance and safety can be achieved and maintained during its operations. Higher-demanding operational requirements such as reliability, lower environmental impacts, and improved performance under adverse conditions in nuclear power plants, coupled with the complexity and uncertainty of the models, necessitate the use of an increased level of autonomy in the control methods. In the opinion of many researchers, the tasks involved during nuclear reactor design and operation (e.g., design optimization, transient diagnosis, and core reload optimization) involve important human cognition and decisions that may be more easily achieved with intelligent methods such as expert systems, fuzzy logic, neural networks, and genetic algorithms. Many experts in the field of control systems share the idea that a higher degree of autonomy in control of complex systems such as nuclear plants is more easily achievable through the integration of conventional control systems and the intelligent components. Researchers have investigated the feasibility of the integration of fuzzy logic, neural networks, genetic algorithms, and expert systems with the conventional control methods to achieve higher degrees of autonomy in different aspects of reactor operations such as reactor startup, shutdown in emergency situations, fault detection and diagnosis, nuclear reactor alarm processing and diagnosis, and reactor load-following operations, to name a few. With the advancement of new technologies and computing power, it is feasible to automate most of the nuclear reactor control and operation, which will result in increased safety and economical benefits. This study surveys current status, practices, and recent advances made towards developing autonomous control systems for nuclear reactors.

  19. Multivariable Feedback Control of Nuclear Reactors

    Directory of Open Access Journals (Sweden)

    Rune Moen

    1982-07-01

    Full Text Available Multivariable feedback control has been adapted for optimal control of the spatial power distribution in nuclear reactor cores. Two design techniques, based on the theory of automatic control, were developed: the State Variable Feedback (SVF is an application of the linear optimal control theory, and the Multivariable Frequency Response (MFR is based on a generalization of the traditional frequency response approach to control system design.

  20. 10 CFR 74.51 - Nuclear material control and accounting for strategic special nuclear material.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Nuclear material control and accounting for strategic special nuclear material. 74.51 Section 74.51 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) MATERIAL CONTROL AND ACCOUNTING OF SPECIAL NUCLEAR MATERIAL Formula Quantities of Strategic Special Nuclear...

  1. Mater semper incertus est: who's your mummy?

    Science.gov (United States)

    D'alton-Harrison, Rita

    2014-01-01

    In English law, the legal term for father has been given a broad definition but the definition of mother remains rooted in biology with the Roman law principle mater semper certa est (the mother is always certain) remaining the norm. However, motherhood may be acquired through giving birth to a child, by donation of gametes or by caring and nurturing a child so that the identity of the mother is no longer certain particularly in the case of surrogacy arrangements. While the law in the UK may automatically recognise the parental status of a commissioning father in a traditional surrogacy arrangement, the parental status of the commissioning mother is not automatically recognised in either a traditional or a gestational surrogacy arrangement. Thus the maxim mater est quam gestation demonstrat (meaning the mother is demonstrated by gestation) is also not approached consistently in the legal interpretation of parentage or motherhood in surrogacy as against other assisted reproduction methods. This raises questions about the extent to which motherhood should be affected by the method of reproduction and whether the sociological and philosophical concept of motherhood should, in the case of surrogacy, give rise to a new principle of 'mater semper incertus est' (the mother is uncertain). This article will argue that the time has come to move away from a legal definition of 'mother' that is based on biology to one that recognises the different forms of motherhood. © The Author [2014]. Published by Oxford University Press; all rights reserved. For Permissions, please email: journals.permissions@oup.com.

  2. 22 CFR 123.20 - Nuclear related controls.

    Science.gov (United States)

    2010-04-01

    ... of nuclear weapons, or other non-nuclear parts of nuclear weapons systems involving Restricted Data... amended. The technical data or defense services relating to nuclear weapons, nuclear weapons systems or... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Nuclear related controls. 123.20 Section 123.20...

  3. Damper mechanism for nuclear reactor control elements

    Science.gov (United States)

    Taft, William Elwood

    1976-01-01

    A damper mechanism which provides a nuclear reactor control element decelerating function at the end of the scram stroke. The total damping function is produced by the combination of two assemblies, which operate in sequence. First, a tapered dashram assembly decelerates the control element to a lower velocity, after which a spring hydraulic damper assembly takes over to complete the final damping.

  4. Biomechanical characterization of human dura mater.

    Science.gov (United States)

    De Kegel, Dries; Vastmans, Julie; Fehervary, Heleen; Depreitere, Bart; Vander Sloten, Jos; Famaey, Nele

    2018-03-01

    A reliable computational model of the human head is necessary for better understanding of the physical mechanisms of traumatic brain injury (TBI), car-crash investigation, development of protective head gear and advancement of dural replacement materials. The performance and biofidelity of these models depend largely on the material description of the different structures present in the head. One of these structures is the dura mater, the protective layer around the brain. We tested five human dura mater specimens, with samples at different locations, using planar biaxial tests. We describe the resulting stress-strain curves using both the anisotropic Gasser-Ogden-Holzapfel (GOH) model and the isotropic one-term Ogden model. The low-strain section of the curves is also described using a Neo-Hookean formulation. The obtained stress-strain curves reveal highly nonlinear but isotropic behaviour. A significant amount of inter- and intra-specimen variability is noticed, whereby the latter does not seem to be influenced by location. The GOH model achieves the best fit of the individual test data. A simple Neo-Hookean model can only be used with extreme caution, as it does not manage to capture the nonlinear effects present even at low strains. Copyright © 2017 Elsevier Ltd. All rights reserved.

  5. Advanced control system for nuclear power plants

    Energy Technology Data Exchange (ETDEWEB)

    Ikekita, Iwao; Neda, Toshikatsu (Toshiba Corp., Kawasaki, Kanagawa (Japan))

    1983-08-01

    It is necessary to construct and operate safe nuclear power plants at high rate of operation as nuclear power generation increased and the unit capacity became large, and it is important to achieve it economically. In order to attain these requirments, the role played by the monitoring and control techniques is very large. In this paper, the outline of the recent monitoring and control techniques for BWR power stations is described, centering around the new system for reducing the burden of operators and the improvement to increase the reliability of existing equipment and system. The change of the monitoring and control techniques for nuclear power stations during 15 year period is shown, and the merits realized are explained. The central control system called PODIA (Plant Operation by Displayed Information and Automation) was developed by Toshiba in 1975. The DMS (Display and Monitoring System) with two TOSBAC 7/70 process computers and five colored CRTs has been operated. The SPDS (Safety Parameter Display System) is the system for helping operators at the time of emergency. The analogdigital multiloop integrated control system, the use of ICs for and the digitalizing of control systems and so on have improved the reliability. The techniques for raising the reliability and economical efficiency of nuclear power plants hereafter are digital techniques, light transmission and diagnostic techniques.

  6. Fast-acting nuclear reactor control device

    Science.gov (United States)

    Kotlyar, Oleg M.; West, Phillip B.

    1993-01-01

    A fast-acting nuclear reactor control device for moving and positioning a fety control rod to desired positions within the core of the reactor between a run position in which the safety control rod is outside the reactor core, and a shutdown position in which the rod is fully inserted in the reactor core. The device employs a hydraulic pump/motor, an electric gear motor, and solenoid valve to drive the safety control rod into the reactor core through the entire stroke of the safety control rod. An overrunning clutch allows the safety control rod to freely travel toward a safe position in the event of a partial drive system failure.

  7. Autonomous Control of Space Nuclear Reactors

    Science.gov (United States)

    Merk, John

    2013-01-01

    Nuclear reactors to support future robotic and manned missions impose new and innovative technological requirements for their control and protection instrumentation. Long-duration surface missions necessitate reliable autonomous operation, and manned missions impose added requirements for failsafe reactor protection. There is a need for an advanced instrumentation and control system for space-nuclear reactors that addresses both aspects of autonomous operation and safety. The Reactor Instrumentation and Control System (RICS) consists of two functionally independent systems: the Reactor Protection System (RPS) and the Supervision and Control System (SCS). Through these two systems, the RICS both supervises and controls a nuclear reactor during normal operational states, as well as monitors the operation of the reactor and, upon sensing a system anomaly, automatically takes the appropriate actions to prevent an unsafe or potentially unsafe condition from occurring. The RPS encompasses all electrical and mechanical devices and circuitry, from sensors to actuation device output terminals. The SCS contains a comprehensive data acquisition system to measure continuously different groups of variables consisting of primary measurement elements, transmitters, or conditioning modules. These reactor control variables can be categorized into two groups: those directly related to the behavior of the core (known as nuclear variables) and those related to secondary systems (known as process variables). Reliable closed-loop reactor control is achieved by processing the acquired variables and actuating the appropriate device drivers to maintain the reactor in a safe operating state. The SCS must prevent a deviation from the reactor nominal conditions by managing limitation functions in order to avoid RPS actions. The RICS has four identical redundancies that comply with physical separation, electrical isolation, and functional independence. This architecture complies with the

  8. Agencia de autocuidado y factores de riesgo cardiovascular en adolescentes

    Directory of Open Access Journals (Sweden)

    Rosa del Socorro Morales Aguilar

    2016-05-01

    Full Text Available Objetivo: Este estudio tuvo como objetivo determinar la relación entre la capacidad de agencia de autocuidado y los factores de riesgo cardiovascular en adolescentes de una Institución de Educación Superior en el Distrito de Barranquilla, Colombia. Metodología: Estudio descriptivo, exploratorio, de corte transversal, con abordaje cuantitativo, basado en la Teoría del Déficit de Autocuidado de Dorothea Orem. La muestra fue compuesta por 133 adolescentes, seleccionados mediante muestreo aleatorio simple. Se aplicaron la Escala Apreciación de la Agencia de Autocuidado (segunda versión en español, el Cuestionario Internacional de Actividad Física (versión corta y la Encuesta Mundial de Tabaquismo en Jóvenes. Para el análisis de los niveles de significancia se utilizó la prueba de Kruskal-Wallis para muestras independientes. Resultados: La mayor parte de los participantes presentó niveles de capacidad de agencia de autocuidado media y alta respectivamente. De acuerdo con la identificación de los factores de riesgo para enfermedad cardiovascular, se evidenció que los adolescentes presentaron probabilidades de desarrollar alguna enfermedad cardiovascular hacia el futuro, dado el comportamiento de los factores de riesgo, como son la obesidad y el sedentarismo. En cuanto a la relación entre la capacidad de agencia de autocuidado y los factores de riesgo, se encontró asociación significativa al relacionar la capacidad de agencia de autocuidado con las categorías de clasificación de la presión arterial. Conclusiones: Los resultados encontrados en el presente estudio coinciden con lo hallado por otros investigadores que afirman que el sedentarismo y la obesidad son los factores de riesgo con mayor presencia en los adolescentes. De igual manera, los hallazgos indican que los adolescentes mostraron capacidad de agencia de autocuidado de nivel medio, pero sólo se encontró asociaci

  9. Controlled Nuclear Fusion: Status and Outlook

    Science.gov (United States)

    Rose, David J.

    1971-01-01

    Presents the history, current concerns and potential developments of nuclear fusion as a major energy source. Controlled fusion research is summarized, technological feasibility is discussed and environmental factors are examined. Relationships of alternative energy sources as well as energy utilization are considered. (JM)

  10. Reactivity control assembly for nuclear reactor. [LMFBR

    Science.gov (United States)

    Bollinger, L.R.

    1982-03-17

    This invention, which resulted from a contact with the United States Department of Energy, relates to a control mechanism for a nuclear reactor and, more particularly, to an assembly for selectively shifting different numbers of reactivity modifying rods into and out of the core of a nuclear reactor. It has been proposed heretofore to control the reactivity of a breeder reactor by varying the depth of insertion of control rods (e.g., rods containing a fertile material such as ThO/sub 2/) in the core of the reactor, thereby varying the amount of neutron-thermalizing coolant and the amount of neutron-capturing material in the core. This invention relates to a mechanism which can advantageously be used in this type of reactor control system.

  11. Los cambios en el control de mando en las firmas según la teoría de agencia: una hipótesis para explicar el surgimiento del Sindicato Antioqueño Los cambios en el control de mando en las firmas según la teoría de agencia: una hipótesis para explicar el surgimiento del Sindicato Antioqueño

    Directory of Open Access Journals (Sweden)

    Diana Londoño Correa

    2005-12-01

    Full Text Available En este artículo se sintetizan los planteamientos de la teoría de agencia y se hace énfasis enla vertiente positivista de esta teoría, la cual muestra fortalezas para explicar el surgimientodel Sindicato Antioqueño, hoy llamado Grupo Empresarial Antioqueño (GEA, uno de losgrandes grupos económicos colombianos. En este trabajo se muestra cómo los intereses delos administradores de las empresas y de un grupo de los accionistas guiaron las actividadesque dieron como resultado el entrecruce de acciones entre empresas a partir del cual se hancoordinado las operaciones de un conjunto de sociedades con sede en Medellín. Este documentoes un subproducto de la investigación “Caracterización del centro corporativo del SindicatoAntioqueño” realizada en el marco de la Maestría en Ciencias de la Administración de laUniversidad EAFIT.This paper reviews the main aspects of the agency theory, and emphasizes on the positivist line, which shows strengths in explaining the birth of the Sindicato Antioqueño or the Grupo Empresarial Antioqueño (GEA, recognized as one of the largest Colombian economic groups. The main conclusion is that the managers’ interests as well as those of a group of shareholders where the ones pursued, and that in the process, cross ownership between the companies were established. This article is a result of the research “Characterization of the Sindicato Antioqueños´s Head Quarters”.

  12. Estudo do sistema normativo contabilístico das microentidades: sua utilidade na perspetiva da entidade e dos profissionais da contabilidade

    OpenAIRE

    Araújo, Cátia Sofia Oliveira Cerqueira

    2017-01-01

    Dissertação de mestrado em Contabilidade As micro e pequenas entidades assumem um papel importante na dinâmica económica de Portugal e da Europa, pela sua representatividade no tecido empresarial. Neste sentido, a União Europeia (UE) tem vindo a estabelecer medidas que aliviem a carga administrativa e contabilístico-financeira do grupo das pequenas empresas, com vista à melhoria do seu ambiente empresarial e internacionalização. É neste âmbito que em Portugal é publicada a N...

  13. Controlling a nuclear spin in a nanodiamond

    Science.gov (United States)

    Knowles, Helena S.; Kara, Dhiren M.; Atatüre, Mete

    2017-09-01

    The sensing capability of a single optically bright electronic spin in diamond can be enhanced by making use of proximal dark nuclei as ancillary spins. Such systems, so far realized only in bulk diamond, can provide orders of magnitude higher sensitivity and spectral resolution in the case of magnetic sensing, as well as improved readout fidelity and state storage time in quantum information schemes. Nanodiamonds offer opportunities for scanning and embedded nanoscale probes, yet electronic-nuclear spin complexes have so far remained inaccessible. Here, we demonstrate coherent control of a 13C nuclear spin located 4 Å from a nitrogen-vacancy center in a nanodiamond and show coherent exchange between the two components of this hybrid spin system. We extract a free precession time T2* of 26 μ s for the nuclear spin, which exceeds the bare-electron free-precession time in nanodiamond by two orders of magnitude.

  14. Control of radioactive waste in nuclear medicine; Controle de rejeitos radioativos em medicina nuclear

    Energy Technology Data Exchange (ETDEWEB)

    Staevie, G.L.G.; Gattringer, D.K.; Tessmann, M.; Dal Mas, C.R. [Pontificia Univ. Catolica do Rio Grande do Sul, Porto Alegre, RS (Brazil). Hospital Sao Lucas

    1996-12-31

    A collection of data about the control of waste in nuclear medicine of Hospital Sao Lucas of PUCRS, Porto Alegre, RS (Brazil) is presented. Better procedures of storing and decrease radioactive waste and improve the service are proposed

  15. Fission control system for nuclear reactor

    Science.gov (United States)

    Conley, G.H.; Estes, G.P.

    Control system for nuclear reactor comprises a first set of reactivity modifying rods fixed in a reactor core with their upper ends stepped in height across the core, and a second set of reactivity modifying rods movable vertically within the reactor core and having their lower ends stepped to correspond with the stepped arrangement of the first set of rods, pairs of the rods of the first and second sets being in coaxial alignment.

  16. The control of nuclear sector; Le controle du nucleaire

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-07-01

    The Asn is loaded with the control of the nuclear safety and the radiation protection in France: it provides this control, in the name of the state, to protect the workers, the patients, the public and the environment of the risks in relation with nuclear activities. The control is the core business of Asn. Asn so checks the nuclear basic installations (I.N.B.), since their conception until their dismantling, the pressure equipment specially conceived for these installations, the management of the radioactive waste as well as the transport of radioactive substances. Asn also checks all the industrial and research installations as well as the hospitals where are used ionizing radiations. It is a more recent profession there, because dating the reform of the control of the nuclear power of 2002, which constitutes that of the radiation protection. The first responsibility of the activities at risks falls to the one who begins them. This principle applies to all the sectors checked by Asn: an industrialist is responsible for the safety of the nuclear installations which he exploits, a doctor is responsible for the use of the ionizing radiations which he uses. (N.C.)

  17. Retención de clientes en agencias de eventos

    Directory of Open Access Journals (Sweden)

    Claudia Gómez-Ramírez

    2011-01-01

    Full Text Available Como componente de la mezcla de comunicación efectiva para las marcas se encuentran los "Eventos", que hoy en día exigen una gestión estratégica. Resulta clave, para las organizaciones especializadas en la prestación de este servicio, aplicar herramientas que les permitan ser competitivas a largo plazo gracias a la diferenciación. Para ello, el CESA ha estudiado la relación cliente-agencia de comunicación de marketing, fundamentalmente respecto a la importancia de la retención de clientes en relaciones B2B, como las que se llevan a cabo entre agencias de eventos y sus clientes. En el presente artículo se exponen los principales hallazgos de una investigación de tipo exploratorio acerca del tema de retención de clientes, que incluye perfiles, elementos claves para la satisfacción y factores relevantes de la relación clienteagencia de eventos como elementos fundamentales de la gestión empresarial. Al tener un mayor conocimiento del perfil de los clientes, las agencias podrán ser más productivas y competitivas, pues estarán en capacidad de ofrecer iniciativas de servicios con características particulares.

  18. ¿Las agencias son unidades administrativas especiales?

    Directory of Open Access Journals (Sweden)

    Consuelo Sarria

    2015-06-01

    Full Text Available Al plantearse como tema del artículo el de si las agencias son unidades administrativas especiales, el trabajo debe abordar dos conceptos aparentemente diferentes en cuanto al contenido y la génesis, pues de un lado se tiene conocimiento de las unidades administrativas especiales creadas con la finalidad de realizar actividades propias de un ministerio o departamento administrativo, y que, en consecuencia, siguiendo lineamientos jurisprudenciales, debían formar parte de la estructura de aquellos o estos. No obstante el reproche doctrinal referido a que a ciertas unidades administrativas se les otorgaba personería jurídica, llama la atención el cambio de criterio jurisprudencial que las avaló, y la manera en que a partir de la Constitución de 1991 se regularon unidades con o sin personería jurídica. Al abordar el tema de las agencias del Estado resulta relevante el origen anglosajón del término y la ausencia de características que las identifiquen, y la ausencia de un régimen común. Se hace especial mención a la reforma de 2011 y a cómo se crearon varias Agencias del Estado, algunas definidas como Unidades Administrativas Especiales, ante lo que cabe interrogarse sobre la correspondencia entre ambas nociones.

  19. Nuclear reactor shutdown control rod assembly

    Science.gov (United States)

    Bilibin, Konstantin

    1988-01-01

    A temperature responsive, self-actuated nuclear reactor shutdown control rod assembly 10. The upper end 18 of a lower drive line 17 fits within the lower end of an upper drive line 12. The lower end (not shown) of the lower drive line 17 is connected to a neutron absorber. During normal temperature conditions the lower drive line 17 is supported by detent means 22,26. When an overtemperature condition occurs thermal actuation means 34 urges ring 26 upwardly sufficiently to allow balls 22 to move radially outwardly thereby allowing lower drive line 17 to move downwardly toward the core of the nuclear reactor resulting in automatic reduction of the reactor powder.

  20. "Mater puerorum'. A medieval naming for an enigmatic children's disease.

    Science.gov (United States)

    Kottek, S S

    1981-09-01

    The pediatric clinical entity called "Mater Puerorum' appears first in the latin translation of Rhazes' "Practica Puerorum' and in his "Continens'. His descriptions of the disease could give some likeness either to a diagnosis of night terrors, or of hyperpyretic convulsions, or of a slight form of epilepsy. Mater Puerorum is afterwards described by most pediatric authors till the Renaissance period without much originality. Rhazes being one of their main sources anyway. Mater Puerorum has been considered by Still and Radbill as a synonym for hysterical fits in children. Going back to the Arabic original naming: Ummu's Sibyan, we venture another etymology based on Babylonian-Judeo-Arabic demonology. The "Mother of the Children' could be the female demon Karina--or Lilith--which is said to come to plague the children at night. The naming Mater Puerorum could thus be ascribed to a folklore origin, rather than to hysteria.

  1. Collective control of a nuclear reactor

    Energy Technology Data Exchange (ETDEWEB)

    Rognin, L.

    1995-06-01

    Nowadays, mainly related to the increasing complexity of working environments, working activities become more and collective. The present research on the paradoxical nature of working teams, considered from a reliability point of view. This document is composed of four Sections. The first Section introduces the context of the research, its objectives and the underlying assumptions. In the second Section, we describe a working situation, which is the control of a nuclear reactor. Relations between cooperative work and reliability are discussed in the third Section. Finally, in the fourth Section, a synthesis of the research and some perspectives are proposed. (authors). 7 refs.

  2. Análisis estadístico de las actuaciones inspectoras (Agencia Estatal de la Administración Tributaria. Periodo: 1995-2000)

    OpenAIRE

    Andrés Aucejo, Eva; Royuela Mora, Vicente

    2003-01-01

    El presente informe tiene como finalidad analizar estadísticamente los conflictos que origina la actuación de los órganos de inspección encuadrados en la Agencia Estatal de la Administración Tributaria a través del estudio descriptivo de las actuaciones de control realizadas por la Inspección de Tributos.

  3. Retención de clientes en agencias de eventos

    OpenAIRE

    Claudia Gómez-Ramírez

    2011-01-01

    Como componente de la mezcla de comunicación efectiva para las marcas se encuentran los "Eventos", que hoy en día exigen una gestión estratégica. Resulta clave, para las organizaciones especializadas en la prestación de este servicio, aplicar herramientas que les permitan ser competitivas a largo plazo gracias a la diferenciación. Para ello, el CESA ha estudiado la relación cliente-agencia de comunicación de marketing, fundamentalmente respecto a la importancia de la retención de clientes en ...

  4. Problema de la agencia y la cultura corporativa estalinista

    OpenAIRE

    Yurí Gorbaneff

    2004-01-01

    El problema de la agencia es de los obstáculos para la eficiencia de las organizaciones. A partir de Alchian y Demsetz (1972).la teoría sugiere dos soluciones: la propiedad privada y la cultura corporativa. Sin embargo, aislar el efecto de la cultura sobre las organizaciones no es fácil. La "ingeniería social" estalinista ofrece un material interesante para evaluar los efectos de la cultura corporativa sobre el sistema económico. Acá se sostiene la hipótesis de que los dirigentes soviético...

  5. Agencia de autocuidado y factores de riesgo cardiovascular en adolescentes

    OpenAIRE

    Rosa del Socorro Morales Aguilar; Magda Lucia Flórez Flórez

    2016-01-01

    Objetivo: Este estudio tuvo como objetivo determinar la relación entre la capacidad de agencia de autocuidado y los factores de riesgo cardiovascular en adolescentes de una Institución de Educación Superior en el Distrito de Barranquilla, Colombia. Metodología: Estudio descriptivo, exploratorio, de corte transversal, con abordaje cuantitativo, basado en la Teoría del Déficit de Autocuidado de Dorothea Orem. La muestra fue compuesta por 133 adolescentes, seleccionados mediante muestreo aleator...

  6. Plasma Physics and Controlled Nuclear Fusion

    CERN Document Server

    Miyamoto, Kenro

    2005-01-01

    The primary objectives of this book are, firstly, to present the essential theoretical background needed to understand recent fusion research and, secondly, to describe the current status of fusion research for graduate students and senior undergraduates. It will also serve as a useful reference for scientists and engineers working in the related fields. In Part I, Plasma Physics, the author explains the basics of magneto-hydrodynamics and kinetic theory in a simple and compact way and, at the same time, covers important new topics for fusion studies such as the ballooning representation, instabilities driven by energetic particles and various plasma models for computer simulations. Part II, Controlled Nuclear Fusion, attempts to review the "big picture" in fusion research. All important phenomena and technologies are addressed, with a particular emphasis on the topics of most concern in current research.

  7. Safety regulations of fuzzy-logic control to nuclear reactors

    OpenAIRE

    Ruan, Da

    2000-01-01

    We present an R&D project on fuzzy-logic control applications to the Belgian Nuclear Reactor 1 (BR1) at the Belgian Nuclear Research Centre (SCK•CEN). The project started in 1995 and aimed at investigating the added value of fuzzy logic control for nuclear reactors. We first review some relevant literature on fuzzy logic control in nuclear reactors, then present the state-of-the-art of the BR1 project, with an understanding of the safety requirements for this real fuzzy-logic control ...

  8. 10 CFR 74.41 - Nuclear material control and accounting for special nuclear material of moderate strategic...

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Nuclear material control and accounting for special nuclear material of moderate strategic significance. 74.41 Section 74.41 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) MATERIAL CONTROL AND ACCOUNTING OF SPECIAL NUCLEAR MATERIAL Special Nuclear Material...

  9. 10 CFR 74.31 - Nuclear material control and accounting for special nuclear material of low strategic significance.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Nuclear material control and accounting for special nuclear material of low strategic significance. 74.31 Section 74.31 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) MATERIAL CONTROL AND ACCOUNTING OF SPECIAL NUCLEAR MATERIAL Special Nuclear Material of Low...

  10. Electronic dura mater for long-term multimodal neural interfaces

    Science.gov (United States)

    Minev, Ivan R.; Musienko, Pavel; Hirsch, Arthur; Barraud, Quentin; Wenger, Nikolaus; Moraud, Eduardo Martin; Gandar, Jérôme; Capogrosso, Marco; Milekovic, Tomislav; Asboth, Léonie; Torres, Rafael Fajardo; Vachicouras, Nicolas; Liu, Qihan; Pavlova, Natalia; Duis, Simone; Larmagnac, Alexandre; Vörös, Janos; Micera, Silvestro; Suo, Zhigang; Courtine, Grégoire; Lacour, Stéphanie P.

    2015-01-01

    The mechanical mismatch between soft neural tissues and stiff neural implants hinders the long-term performance of implantable neuroprostheses. Here, we designed and fabricated soft neural implants with the shape and elasticity of dura mater, the protective membrane of the brain and spinal cord. The electronic dura mater, which we call e-dura, embeds interconnects, electrodes, and chemotrodes that sustain millions of mechanical stretch cycles, electrical stimulation pulses, and chemical injections. These integrated modalities enable multiple neuroprosthetic applications. The soft implants extracted cortical states in freely behaving animals for brain-machine interface and delivered electrochemical spinal neuromodulation that restored locomotion after paralyzing spinal cord injury.

  11. Nuclear Forensic Science: Analysis of Nuclear Material Out of Regulatory Control

    Science.gov (United States)

    Kristo, Michael J.; Gaffney, Amy M.; Marks, Naomi; Knight, Kim; Cassata, William S.; Hutcheon, Ian D.

    2016-06-01

    Nuclear forensic science seeks to identify the origin of nuclear materials found outside regulatory control. It is increasingly recognized as an integral part of a robust nuclear security program. This review highlights areas of active, evolving research in nuclear forensics, with a focus on analytical techniques commonly employed in Earth and planetary sciences. Applications of nuclear forensics to uranium ore concentrates (UOCs) are discussed first. UOCs have become an attractive target for nuclear forensic researchers because of the richness in impurities compared to materials produced later in the fuel cycle. The development of chronometric methods for age dating nuclear materials is then discussed, with an emphasis on improvements in accuracy that have been gained from measurements of multiple radioisotopic systems. Finally, papers that report on casework are reviewed, to provide a window into current scientific practice.

  12. Transformaciones performativas: agencia y vulnerabilidad en Judith Butler

    Directory of Open Access Journals (Sweden)

    Mónica Cano Abadía

    2015-02-01

    Full Text Available El objetivo de este artículo es analizar cómo la teoría de la performatividad de Judith Butler posibilita pensar la capacidad de acción y resistencia de los sujetos. Butler propone deconstruir la categoría de identidad a través de la performatividad, que nos permite pensarnos como sujetos en el límite, interdependientes y vulnerables. Al considerarnos como seres performativos y, además, vulnerables a nuestras interacciones tanto con el contexto como con las demás personas, todo cuestionamiento de las normas sociales que nos rodean llevarán irremediablemente a una transformación del propio yo. Esta transformación que comienza en nuestras propias identidades, conduce a otra manera de entender lo humano y a otra forma de plantear nuestras agencias políticas.

  13. Viscoelastic finite-element analysis of human skull - dura mater ...

    African Journals Online (AJOL)

    SERVER

    2008-03-18

    Mar 18, 2008 ... Key words: Viscoelasticity, finite-element analysis (FEA), strain, human skull, dura mater, intracranial pressure. INTRODUCTION. Intracranial pressure (ICP) is the ... We presented the development and validation of a 3D finite-element model intended to better understand the deformation mechanisms of ...

  14. Viscoelastic finite-element analysis of human skull - dura mater ...

    African Journals Online (AJOL)

    SERVER

    2008-03-18

    Mar 18, 2008 ... 1981). MATERIALS AND METHODS. In order to determine the influence of the viscoelastic nature of the human skull and dura mater on their deformation, we made the finite-element analysis of cranial cavity with the ICP scope from 1.5 to 5 kPa respectively. By ignoring the viscoelasticity of human skull.

  15. Viscoelastic finite-element analysis of human skull - dura mater ...

    African Journals Online (AJOL)

    In the work, the dynamic characteristics of the human skull-dura mater system were studied. For the purpose of our analysis, we adopted a model consisted of a hollow sphere. By using the 'Patran and. Ansys' finite element processor, a simplified three-dimensional finite element model (FEM) of a human skull was ...

  16. Insurer risk control and nuclear liability

    Energy Technology Data Exchange (ETDEWEB)

    DeMerchant, C. [Nuclear Insurance Association of Canada, Toronto, ON (Canada)

    2015-07-01

    We specialize in high quality insurance risk management, underwriting and inspections for Canadian nuclear exposures. We provide true risk transfer, secure insurance capacity and collaborate with the world's nuclear experts to create innovative domestic solutions for our clients and members. The benefit of our experience works for all stake holders: insured clients, members, multi-level government agencies and all Canadians. NIAC has a 55-year history of partnering with insurers around the globe to create reliable risk management for the nuclear industry. We offer Canadian risk solutions, thought leadership and expertise that provides security and confidence to our customers and members. NIAC leads in the areas of nuclear insurance law, good governance and claims administration to create a true Centre of Excellence.

  17. Reflexión y nuevos retos de Unibasq, Agencia de Calidad del Sistema Universitario Vasco.

    OpenAIRE

    Fernández de Labastida Amurrio, Eva; Ferreira García, Eva; Zuramendi Isla, Aitor

    2016-01-01

    Unibasq es la Agencia de Calidad del Sistema Universitario Vasco. Creada en 2004, su trayectoria, al igual que en otras agencias, es paralela a la construcción del Espacio Europeo de Educación Superior (EEES). En este artículo analizamos la evolución de Unibasq, los cambios de su marco legal y sus competencias, y la visión actual y de futuro. La evolución refleja el aumento continuo de la actividad y la consolidación de la Agencia como asesora en el Sistema Universitario Vasco. Los cam...

  18. Examen de Auditoria Integral al Departamento de Crédito y Cobranza de la Agencia Echeandía

    OpenAIRE

    Garcia Saltos, Washington Renato

    2014-01-01

    El Examen de Auditoria Integral al Departamento de Crédito y Cobranza de la Agencia Echeandía de la Cooperativa de Ahorro y Crédito Guaranda Limitada, se realizó aplicando las etapas de Auditoria de Control Interno, Cumplimiento, Gestión y Financiera. Se inició la auditoría con el análisis del Estatuto Social, Planes Estratégico, Operativo y Presupuestario, Orgánico Estructural, Manual de Crédito y Estados Financieros, para obtener una visión general del componente a auditar, posteriormente ...

  19. Agencia de autocuidado y adherencia al tratamiento en personas con factores de riesgo cardiovascular

    National Research Council Canada - National Science Library

    Velandia-Arias, Anita; Rivera-Alvarez, Luz N

    2009-01-01

    Metodos Diseno descriptivo correlacional que midio y relaciono la Agencia de autocuidado y la Adherencia a los tratamientos en una muestra de 201 personas que contaban con algun factor de riesgo cardiovascular...

  20. Collagen-inspired self-assembling materals

    NARCIS (Netherlands)

    Skrzeszewska, P.J.

    2011-01-01

      The rapid increase of the quality of life together with the progress of medical science asks for the development of new, tuneable and controllable materials. For the same reason, materials used for biomedical applications have to be increasingly biocompatible, biodegradable and

  1. Proliferation of nuclear weapons: opportunities for control and abolition.

    Science.gov (United States)

    Sidel, Victor W; Levy, Barry S

    2007-09-01

    Nuclear weapons pose a particularly destructive threat. Prevention of the proliferation and use of nuclear weapons is urgently important to public health. "Horizontal" proliferation refers to nation-states or nonstate entities that do not have, but are acquiring, nuclear weapons or developing the capability and materials for producing them. "Vertical" proliferation refers to nation-states that do possess nuclear weapons and are increasing their stockpiles of these weapons, improving the technical sophistication or reliability of their weapons, or developing new weapons. Because nation-states or other entities that wish to use or threaten to use nuclear weapons need methods for delivering those weapons, proliferation of delivery mechanisms must also be prevented. Controlling proliferation--and ultimately abolishing nuclear weapons--involves national governments, intergovernmental organizations, nongovernmental and professional organizations, and society at large.

  2. ANÁLISIS DEL SECTOR DE LAS AGENCIAS DE VIAJES EN ESPAÑA: UNA APROXIMACIÓN DESDE LA CARACTERIZACIÓN DEL SECTOR ENTRE LAS AGENCIAS DE VIAJES TRADICIONALES Y LAS AGENCIAS DE VIAJES ONLINE

    Directory of Open Access Journals (Sweden)

    Luis Lacalle Muñoz

    2013-06-01

    Full Text Available El sector de las agencias de viajes español está sufriendo en los últimos años una importantísima transformación. El número de agencias se ha visto reducido de manera drástica y la composición de la industria también se ha visto alterada. Por otra parte, cada vez es mayor el número de agencias online que desplazan a aquellas que realizan su labor de intermediación de una manera tradicional. No sólo en número sino también atendiendo a la cuota de mercado. El presente artículo además de presentar una aproximación al criterio de división entre agencias tradicionales y online, ofrece una perspectiva de la actual composición y reciente evolución del sector.

  3. Collagen-inspired self-assembling materals

    OpenAIRE

    Skrzeszewska, P.J.

    2011-01-01

      The rapid increase of the quality of life together with the progress of medical science asks for the development of new, tuneable and controllable materials. For the same reason, materials used for biomedical applications have to be increasingly biocompatible, biodegradable and biofunctional. Most of the available systems, however, lack one property or the other. For example, conventional animal-derived gelatin that is often used in biomedicine, is susceptible to a risk of contaminatio...

  4. CAPACIDAD DE AGENCIA DE AUTOCUIDADO EN LAS PERSONAS ADULTAS QUE PADECEN ARTRITIS REUMATOIDE

    Directory of Open Access Journals (Sweden)

    Viriam Leiva Díaz

    2012-04-01

    Full Text Available El objetivo de la investigación consistió en analizar la capacidad de agencia de autocuidado que poseen laspersonas con diagnóstico de artritis reumatoide, quienes habitan en los cantones de Palmares y San Ramón. Se desarrolló una metodología de investigación cuantitativa de tipo descriptiva transversal. En cuanto a la población participante del estudio, estuvo conformada por 13 personas diagnosticadas con artritis reumatoide; respecto de los instrumentos utilizados para recolectar información, a los colaboradores se les aplicó el instrumento “Escala de apreciación de la capacidad de agencia de autocuidado”, propuesta por Dorothea Orem. Se determinó que los participantes poseen alta capacidad de agencia de autocuidado en las diferentes categorías, ya que únicamente se detectó baja capacidad de agencia de autocuidado en cuanto a interacción social (2 personas, y respecto del consumo insuficiente de alimentos (5 personas. La escala ASA permite a la Enfermera (o determinar la capacidad de agencia de autocuidado, de forma oportuna y eficaz. Además, permitió a las investigadoras observar un panorama general de las necesidades de autocuidado de la población participante y constatar que esta presenta alta capacidad de agencia de autocuidado.

  5. A problemática contabilística dos ativos fixos tangíveis e os efeitos de uma cultura marcada pelos contributos e influências fiscais - o caso do setor dos transportes rodoviários de passageiros

    OpenAIRE

    Santos, Filipe José Cardoso dos

    2016-01-01

    Mestrado em Contabilidade A forte globalização dos mercados, a existência de um ambiente empresarial muito competitivo e o elevado nível de conhecimento dos stakeholdres, tem exigido às empresas informação financeira (IF) com elevada qualidade e competência. Na persecução deste objetivo, em Portugal, a 1 de janeiro de 2010, é introduzido o Sistema de Normalização Contabilística (SNC). Trata-se de um modelo de normalização contabilística assente no normativo internacional (IAS/IFRS), vin...

  6. Impacto da adoção do sistema de normalização contabilística - entidades do setor não lucrativo (SNC-ESNL) nas Santas Casas da Misericórdia: estudo de caso

    OpenAIRE

    Alegria, Maykol A.; Ribeiro, Nuno A.; Nogueira, Sónia P.

    2014-01-01

    Este estudio tiene como objetivo entender el impacto que la implementación del “Sistema de Normalização Contabilística - Entidades do Setor Não Lucrativo” en los estados financieros de la “Santa Casa daMisericórdia do Porto”, en 2011. En concreto, se pretende evaluar los impactos de la im plementación del“Sistema de Normalização Contabilística - Entidades do Setor Não Lucrativo”, en las diferentes rubricas de los estados financieros (balance y cuenta de resultados) y ciertos...

  7. Regulatory control of nuclear safety in Finland. Annual report 1999

    Energy Technology Data Exchange (ETDEWEB)

    Tossavainen, K. [ed.

    2000-06-01

    This report concerns the regulatory control of nuclear energy in Finland in 1999. Its submission to the Ministry of Trade and Industry by the Finnish Radiation and Nuclear Safety Authority (STUK) is stipulated in section 121 of the Nuclear Energy Decree. STUK's regulatory work was focused on the operation of the Finnish nuclear power plants as well as on nuclear waste management and safeguards of nuclear materials. The operation of the Finnish nuclear power plants was in compliance with the conditions set out in their operating licences and with current regulations, with the exception of some inadvertent deviations from the Technical Specifications. No plant events endangering the safe use of nuclear energy occurred. The individual doses of all nuclear power plant workers remained below the dose threshold. The collective dose of the workers was low, compared internationally, and did not exceed STUK's guidelines at either nuclear power plant. The radioactive releases were minor and the dose calculated on their basis for the most exposed individual in the vicinity of the plant was well below the limit established in a decision of the Council of State at both Loviisa and Olkiluoto nuclear power plants. STUK issued statements to the Ministry of Trade and Industry about the environmental impact assessment programme reports on the possible nuclear power plant projects at Olkiluoto and Loviisa and about the continued operation of the research reactor in Otaniemi, Espoo. A Y2k-related safety assessment of the Finnish nuclear power plants was completed in December. In nuclear waste management STUK's regulatory work was focused on spent fuel storage and final disposal plans as well as on the treatment, storage and final disposal of reactor waste. No events occurred in nuclear waste management that would have endangered safety. A statement was issued to the Ministry of Trade and Industry about an environmental impact assessment report on a proposed final

  8. Nuclear electric power safety, operation, and control aspects

    CERN Document Server

    Knowles, J Brian

    2013-01-01

    Assesses the engineering of renewable sources for commercial power generation and discusses the safety, operation, and control aspects of nuclear electric power From an expert who advised the European Commission and UK government in the aftermath of Three Mile Island and Chernobyl comes a book that contains experienced engineering assessments of the options for replacing the existing, aged, fossil-fired power stations with renewable, gas-fired, or nuclear plants. From geothermal, solar, and wind to tidal and hydro generation, Nuclear Electric Power: Safety, Operation, and Control Aspects ass

  9. Relación de agencia y monopolio. El caso del tabaco en España (1887-1986

    Directory of Open Access Journals (Sweden)

    Eva Chamorro

    2016-01-01

    Full Text Available Los análisis históricos contables permiten evidenciar, bajo el marco de la teoría de la agencia, los conflictos de intereses que se producen en una organización. Nuestro objetivo, con un estudio longitudinal, basado en fuentes primarias, es comprobar cómo se regula una relación de agencia a través de contratos formales, y el papel que asume la contabilidad. El caso en el que nos basamos, y que puede ser una importante contribución en ese sentido, es el del arrendamiento del monopolio estatal del tabaco a una empresa privada, desde el inicio de la gestión (1887 hasta que empieza a desaparecer esta actividad monopolística (1986. Nuestros hallazgos ponen de manifiesto que los contratos establecidos permiten un gran control del principal sobre el agente y que no se cumplen todas las condiciones que deben darse para considerarlos «un buen acuerdo contractual». Por otro lado, la contabilidad aparece como un instrumento clave para el control del Estado sobre las empresas arrendatarias. Nuestra principal conclusión es que el agente es quien asume mayor riesgo en el arrendamiento, y el principal mantiene un comportamiento oportunista durante todo el periodo, lo que contradice los planteamientos más generalizados de la teoría y permite relajar sus asunciones iniciales.

  10. Ensino médio e ensino técnico na América Latina: Brasil, Argentina e Chile Mid level schooling and vocational training in Latin America: Brazil, Argentina and Chile

    Directory of Open Access Journals (Sweden)

    Luiz Antônio Cunha

    2000-12-01

    Full Text Available O artigo analisa políticas educacionais em três países latino-americanos (Brasil, Argentina e Chile, nos anos 80 e 90, comparando-as, em cada país, com as das décadas anteriores, assim como entre uns e outros. Como foco de análise, o autor tomou a educação intermediária, definida como a posicionada entre a educação obrigatória e a educação superior. As políticas para esse segmento, em cada país, foram examinadas com referência à persistência e/ou à mudança da dualidade estrutural. A conclusão do autor é a de que Brasil e Argentina elaboraram e implementam políticas tendentes ao reforço da dualidade, ao passo que o Chile anuncia políticas de sua atenuação.This article analyzes educational policy in three Latin American countries (Brazil, Argentina and Chile during the 80s and 90s, making comparisons within each country in relation to earlier decades, as well as among the countries. With an analytical focus the author takes mid level schooling defined as that which occurs between obligatory schooling and higher education. The policies for this segment in each country, were examined with reference to the persistence and/or change of the structural duality. The author's conclusion is that Brazil and Argentina have developed and implemented policies tending to reinforce this duality, and that Chile has articulated policies to attenuate it.

  11. Control of nuclear organization by F-actin binding proteins.

    Science.gov (United States)

    Pfisterer, Karin; Jayo, Asier; Parsons, Maddy

    2017-03-04

    The regulation of nuclear shape and deformability is a key factor in controlling diverse events from embryonic development to cancer cell metastasis, but the mechanisms governing this process are still unclear. Our recent study demonstrated an unexpected role for the F-actin bundling protein fascin in controlling nuclear plasticity through a direct interaction with Nesprin-2. Nesprin-2 is a component of the LINC complex that is known to couple the F-actin cytoskeleton to the nuclear envelope. We demonstrated that fascin, which is predominantly associated with peripheral F-actin rich filopodia, binds directly to Nesprin-2 at the nuclear envelope in a range of cell types. Depleting fascin or specifically blocking the fascin-Nesprin-2 complex leads to defects in nuclear polarization, movement and cell invasion. These studies reveal a novel role for an F-actin bundling protein in control of nuclear plasticity and underline the importance of defining nuclear-associated roles for F-actin binding proteins in future.

  12. Nuclear Arms Control, Nonproliferation, and Counterterrorism: Impacts on Public Health

    Science.gov (United States)

    Pregenzer, Arian

    2014-01-01

    Reducing the risks of nuclear war, limiting the spread of nuclear weapons, and reducing global nuclear weapons stockpiles are key national and international security goals. They are pursued through a variety of international arms control, nonproliferation, and counterterrorism treaties and agreements. These legally binding and political commitments, together with the institutional infrastructure that supports them, work to establish global norms of behavior and have limited the spread of weapons of mass destruction. Beyond the primary security objectives, reducing the likelihood of the use of nuclear weapons, preventing environmental releases of radioactive material, increasing the availability of safe and secure nuclear technology for peaceful purposes, and providing scientific data relevant to predicting and managing the consequences of natural or human-caused disasters worldwide provide significant benefits to global public health. PMID:24524501

  13. Análise de práticas contabilísticas na antiga civilização mesopotâmica = Analysis of accounting practices in the former mesopotamian Civilization

    Directory of Open Access Journals (Sweden)

    Miguel Gonçalves

    2010-01-01

    Full Text Available Constitui um facto perfeitamente verificável que nas últimas décadas se tem vindo a dedicar umaatenção crescente a trabalhos em História da Contabilidade. Antes dos estudos consideradoshoje como fazendo parte da Nova História da Contabilidade, os historiadores da nossa disciplinaconsagraram as suas investigações a aspectos relacionados com a origem e os processosevolutivos da Contabilidade, particularmente no que toca ao exame de práticas contabilísticas emcivilizações antigas. Com base na revisão da literatura de autores não-contabilísticos econtabilísticos (principalmente aqueles que se podem classificar como historiadoresconvencionais da Contabilidade, a questão magna que versamos neste trabalho respeita ànarração resumida de algumas técnicas contabilísticas praticadas no seio da mais antigacivilização da humanidade - a Mesopotâmia.It is a perfectly verifiable fact that in recent decades increasing attention has been devoting to works inAccounting History. Before studies considered today as part of the New Accounting History, historiansof our discipline dedicated their research to aspects on the origin and evolutionary processes ofAccounting, particularly with regard to the examination of accounting practices in ancient civilizations.Based on the review of the literature of non-accounting and Accounting authors, mainly those that canbe classified as conventional Accounting historians, the broader issue discussed in this work thusrelates to the narrative summary of some accounting techniques practiced within the most ancientcivilization of mankind - Mesopotamia.

  14. El papel de las agencias de seguros en la competencia entre compañías aseguradoras

    OpenAIRE

    Leonardo Medrano

    2008-01-01

    Este artículo estudia el mercado de seguros cuando las compañías aseguradoras (aseguradoras) venden sus pólizas por medio de agencias de seguros (agencias o agentes). Analiza los efectos de las comisiones por ventas pagadas a las agencias en las primas de seguros y en el bienestar del consumidor. Se considera el comportamiento oportunista de las agencias al vender las pólizas emitidas por la aseguradora que le ofrece la comisión mas alta. Se consideran también diferentes estructuras de mercad...

  15. Smart Windows: Switching Light Transmittance by Responsive Organometallic Poly(ionic liquid)s: Control by Cross Talk of Thermal and Redox Stimuli (Adv. Funct. Mater. 41/2017)

    NARCIS (Netherlands)

    Zhang, Kaihuan; Zhang, Minmin; Feng, Xueling; Hempenius, Mark A.; Vancso, G. Julius

    2017-01-01

    In article number 1702784, G. Julius Vancso and co-workers report an organometallic polymer with sulfonate side groups for transmittance control. The novel polymer, produced by a simple one-step synthesis, exhibits both a lower critical solution temperature (LCST)-type phase transition and an

  16. Nuclear reactor flow control method and apparatus

    Science.gov (United States)

    Church, J.P.

    1993-03-30

    Method and apparatus for improving coolant flow in a nuclear reactor during accident as well as nominal conditions. The reactor has a plurality of fuel elements in sleeves and a plenum above the fuel and through which the sleeves penetrate. Holes are provided in the sleeve so that coolant from the plenum can enter the sleeve and cool the fuel. The number and size of the holes are varied from sleeve to sleeve with the number and size of holes being greater for sleeves toward the center of the core and less for sleeves toward the periphery of the core. Preferably the holes are all the same diameter and arranged in rows and columns, the rows starting from the bottom of every sleeve and fewer rows in peripheral sleeves and more rows in the central sleeves.

  17. Nuclear Command and Control: Current Programs and Issues

    Science.gov (United States)

    2006-05-03

    Altitude Electromagnetic Pulse ( HEMP ) and High Power Microwave (HPM) Devices: Threat Assessments, by Clay Wilson. 54 Dee Ann Divis, “Protection Not in...Some analysts argue that detonating a high altitude nuclear burst to generate EMP against the U.S. critical infrastructure might be one way that China...infrastructure, including command and control systems, through an electromagnetic pulse (EMP).53 A high altitude nuclear explosion generates an electrical

  18. Regulatory control of nuclear safety in Finland. Annual report 1998

    Energy Technology Data Exchange (ETDEWEB)

    Tossavainen, K. [ed.

    1999-10-01

    The report describes regulatory control of the safe use of nuclear energy by the Radiation and Nuclear Safety Authority (STUK) in 1998. STUK is the Finnish nuclear safety authority. The submission of this report to the Ministry of Trade and Industry is stipulated in Section 121 of the Nuclear Energy Decree. It was verified by regulatory control that the operation of Finnish NPPs was in compliance with conditions set out in the operating licences of the plants and with regulations currently in force. In addition to supervising the normal operation of the plants, STUK oversaw projects carried out at the plant units, which related to the uprating of their power and the improvement of their safety. STUK issued to the Ministry of Trade and Industry a statement about applications for the renewal of the operating licences of Loviisa and Olkiluoto NPPs, which had been submitted by Imatran Voima Oy and Teollisuuden Voima Oy. Regulatory activities in the field of nuclear waste management were focused on the storage and final disposal of spent fuel as well as the treatment, storage and final disposal of reactor waste. STUK issued a statement to the Ministry of Trade and Industry about an environmental impact assessment programme pertaining to a spent fuel repository project, which had been submitted by Posiva Oy, as well as on Imatran Voima Oy's application concerning the operation of a repository for medium- and low-level reactor waste from Loviisa NPP. The use of nuclear materials was in compliance with the regulations currently in force and also the whereabouts of every batch of nuclear material were ensured by safeguards control. In international safeguards, important changes took place, which were reflected also in safeguards activities at national level. International co-operation continued based on financing both from STUK's budget and from additional sources. The focus of co-operation funded from outside sources was as follows: improvement of the safety of

  19. Mutual control of X-rays and nuclear transitions

    Energy Technology Data Exchange (ETDEWEB)

    Gunst, Jonas Friedrich

    2015-12-14

    In the course of this Thesis the mutual control between X-rays and nuclear transitions is investigated theoretically. In the first Part, we study the nuclear photoexcitation with the highly brilliant and coherent X-ray free-electron lasers (XFELs). Apart from amplifying the direct resonant interaction with nuclear transitions, the super-intense XFEL can produce new states of matter like cold, high-density plasmas where secondary nuclear excitation channels may come into play, e.g., nuclear excitation by electron capture (NEEC). Our results predict that in the case of {sup 57}Fe targets secondary NEEC can be safely neglected, whereas it is surprisingly the dominating contribution (in comparison to the direct photoexcitation) for the XFEL-induced {sup 93m}Mo isomer triggering. Based on these case studies, we elaborate a general set of criteria to identify the prevailing excitation channel for a certain nuclear isotope. These criteria may be most relevant for future nuclear resonance experiments at XFEL facilities. On the opposite frontier, the interplay between single X-ray photons and nuclear transitions offer potential storage and processing applications for information science in their most compact form. In the second Part of this Thesis, we show that nuclear forward scattering off {sup 57}Fe targets can be employed to process polarization-encoded single X-rays via timed magnetic field rotations. Apart from the realization of logical gates with X-rays, the polarization encoding is used to design an X-ray quantum eraser scheme where the interference between scattering paths can be switched off and on in a controlled manner. Such setups may advance time-energy complementarity tests to so far unexplored parameter regimes, e.g., to the domain of X-ray quanta.

  20. Tangible interfaces for virtual nuclear power plant control desk

    Energy Technology Data Exchange (ETDEWEB)

    Aghina, Mauricio Alves C.; Mol, Antonio Carlos A.; Jorge, Carlos Alexandre F.; Lapa, Celso M.F. [Instituto de Engenharia Nuclear (IEN/CNEN-RJ), Rio de Janeiro, RJ (Brazil); Nomiya, Diogo [Engenharia Eletrica (UFRJ), Universidade Federal do Rio de Janeiro, RJ (Brazil); Cunha, Gerson G.; Landau, Luiz [Programa de Engenharia Civil (PEC/COPPE/UFRJ), Universidade Federal do Rio de Janeiro, RJ (Brazil)

    2011-07-01

    Due to the high safety requirements for nuclear power plant operation, control desks must be designed in such a way operators can take all the procedures safely, with a good overview of all variable indicators and easy access to actuator controls. Also, operators must see alarms indication in a way they can easily identify any abnormal conditions and bring the NPP back to normal operation. The ergonomics and human factors fields have helped evaluations to improve the design of nuclear power plant control systems. Lately, the use of virtual control desks have helped even more such evaluations, by integrating in one platform both nuclear power plant dynamics simulator with a high visual fidelity control desk proto typing. Operators can interact with these virtual control desks in a similar way as with real ones. Such a virtual control desk has been under development at Instituto de Engenharia Nuclear, IEN/CNEN. This paper reports the latest improvements, with the use of more interaction modes, to turn operation a friendlier task. An automatic speech recognition interface has been implemented as a self-contained system, by accessing directly MS Windows Application Interface, and with online neural network training for spoken commend recognition. Thus, operators can switch among different desk views. Besides this, head tracking interfaces have been integrated with the virtual control desk, to move within desk views according to users head movements. Both marker and markerless-based head tracking interfaces have been implemented. Results are shown and commented. (author)

  1. Use of hafnium in control bars of nuclear reactors; Uso de hafnio en barras de control de reactores nucleares

    Energy Technology Data Exchange (ETDEWEB)

    Ramirez S, J.R.; Alonso V, G. [ININ, 52045 Ocoyoacac, Estado de Mexico (Mexico)]. e-mail: jrrs@nuclear.inin-mx

    2003-07-01

    Recently the use of hafnium as neutron absorber material in nuclear reactors has been reason of investigation by virtue of that this material has nuclear properties as to the neutrons absorption and structural that can prolong the useful life of the control mechanisms of the nuclear reactors. In this work some of those more significant hafnium properties are presented like nuclear material. Also there are presented calculations carried out with the HELIOS code for fuel cells of uranium oxide and of uranium and plutonium mixed oxides under controlled conditions with conventional bars of boron carbide and also with similar bars to which are substituted the absorbent material by metallic hafnium, the results are presented in this work. (Author)

  2. Recent control and instrumentation systems for BWR nuclear power plant

    Energy Technology Data Exchange (ETDEWEB)

    Fujii, Hiroaki; Higashikawa, Yuichi; Sato, Hideyuki (Hitachi Ltd., Tokyo (Japan))

    1990-10-01

    For the needs of the more stable operation of nuclear power stations, the upgrading of the measurement and control system for BWRs has been promoted by positively introducing remarkably advancing electronic technology. Further, it is aimed at to construct the synthetic digitized measurement and control system for nuclear power stations to heighten the operation reliability in ABWRs. As the first step of the development in the synthetic digitization, the monitoring and control system for radioactive waste treatment was put in practical use for No.5 plant of Kashiwazaki, Kariwa Nuclear Power Station, Tokyo Electric Power Co., Inc. Hitachi Ltd. has promoted the development and the application to actual plants of the measurement and control system for BWRs, in which digital control technology, optical information transmission technology and the operation-supporting technology using a computer were utilized. Hereafter, it is intended to expand the application of digital measurement and control aiming at improving the reliability, operation performance and maintainability. The nuclear power plant control complex with advanced man-machine interface-90 (NUCAMM-90) was developed, and its application to actual plants is planned. (K.I.).

  3. Development of Nuclear Control and Management Information Treatment System

    Energy Technology Data Exchange (ETDEWEB)

    Yoo, J. G.; Lee, B. D.; So, D. S. [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2007-07-01

    To implement obligations under the Non-Proliferation Treaty (NPT) and the bilateral agreements more effectively, we proposed a computerized system named the Nuclear Control and Management Information Treatment System (NCAMITS) as a part of the Nuclear Transparency Enhancement Project at the Korea Atomic Energy Research Institute (KAERI). The database system is designed not only to undertake the facility-level accounting for and control of nuclear material at KAERI, but also to meet the requirements of the State (National) System of Accounting and Control (SSAC). Since the NCAMITS will provide services for the facility operators as well as the safeguard information managers at KAERI, the development of the system is supposed to accommodate the end-user's convenience and the manager's sophisticated specifications as well.

  4. Nuclear Instrumentation and Control Cyber Testbed Considerations – Lessons Learned

    Energy Technology Data Exchange (ETDEWEB)

    Jonathan Gray; Robert Anderson; Julio G. Rodriguez; Cheol-Kwon Lee

    2014-08-01

    Abstract: Identifying and understanding digital instrumentation and control (I&C) cyber vulnerabilities within nuclear power plants and other nuclear facilities, is critical if nation states desire to operate nuclear facilities safely, reliably, and securely. In order to demonstrate objective evidence that cyber vulnerabilities have been adequately identified and mitigated, a testbed representing a facility’s critical nuclear equipment must be replicated. Idaho National Laboratory (INL) has built and operated similar testbeds for common critical infrastructure I&C for over ten years. This experience developing, operating, and maintaining an I&C testbed in support of research identifying cyber vulnerabilities has led the Korean Atomic Energy Research Institute of the Republic of Korea to solicit the experiences of INL to help mitigate problems early in the design, development, operation, and maintenance of a similar testbed. The following information will discuss I&C testbed lessons learned and the impact of these experiences to KAERI.

  5. Ética policial: una aproximación desde la agencia*

    Directory of Open Access Journals (Sweden)

    Nidian Johana Sanabria Cárdena

    2012-07-01

    Full Text Available El presente texto se propone mostrar la posibilidad de la agencia desde un curso de ética en el marco de la formación ejecutiva del cuerpo policial. Se partede los avances logrados en las discusiones sobre el concepto de agencia, en particular en la sociología norteamericana. Seguido, se procede a presentar las prácticas desarrolladas con los estudiantes, con el propósito de sugerir posibilidades para dicha agencia desde sí mismos. Y finalmente, se reflexiona sobre las posibilidades de que esta propuesta pueda resultar útil en el desarrollo institucional de la Policía Nacional de Colombia.

  6. SPRING DRIVEN ACTUATING MECHANISM FOR NUCLEAR REACTOR CONTROL

    Science.gov (United States)

    Bevilacqua, F.; Uecker, D.F.; Groh, E.F.

    1962-01-23

    l962. rod in a nuclear reactor to shut it down. The control rod or an extension thereof is wound on a drum as it is withdrawn from the reactor. When an emergency occurs requiring the reactor to be shut down, the drum is released so as to be free to rotate, and the tendency of the control rod or its extension coiled on the drum to straighten itself is used for quickly returning the control rod to the reactor. (AEC)

  7. Educação e hegemonia na América Latina de hoje: projetos de sociedade e de educação nos anos 90: Brasil, Argentina, Chile e Venezuela

    Directory of Open Access Journals (Sweden)

    Adriana Almeida Sales de Melo

    2000-01-01

    Full Text Available Iniciada em março de 1999, esta pesquisa está se desenvolvendo como elemento de meu doutorado em educação. Este trabalho também faz parte do Projeto CORI/MERCOSUL, área temática Educação, desde 1999. Esta investigação tem como tema central a relação entre os diversos projetos de sociedade e de educação dos principais sujeitos políticos coletivos que planejam e atuam na direção atual das políticas educacionais dos países da América Latina. Pretendemos analisar o processo de transição e consolidação democrática do Brasil, Argentina, Chile e Venezuela; bem como o redirecionamento das políticas educacionais nestes ambientes culturais, no sentido de esclarecer as contradições entre as demandas e objetivos dos sujeitos políticos coletivos locais e internacionais em seu movimento de construção de um projeto hegemônico de sociedade e de educação; ora neoliberal, ora democrático de massas. Este tipo de análise pode trazer contribuições reais no sentido da construção e sistematização de elementos de integração entre as diversas identidades históricas e culturais dos nossos países; interferindo sob a forma de novas categorias de investigação, no nosso planejamento e ação educacionais locais. Started in 1999, march, this research is going on as an element of my education doctorate. This work is also part of CORI/MERCOSUL project, at education thematic area, since 1999. This investigation has as central theme the relation between "society and education projects" of the principal politician social subjects that plan and actuate in the actual educational policies directions at Latin America countries. We intend to analyze the democratic transition and consolidation in Brazil, Argentina, Chile and Venezuela; and also the educational policies redirections in these cultural ambiance; in the way to clarify the contradictions between these social subjects demands and objectives in their building process of "society

  8. The future of U.S.-Russia nuclear arms control

    Science.gov (United States)

    Pifer, Steven

    2017-11-01

    Nuclear arms control has long made contributions to U.S.-Soviet and U.S.-Russian security, but the current regime is at risk. The 1987 Intermediate-range Nuclear Forces Treaty may be headed for collapse. Both the United States and Russia are modernizing their strategic forces, and the fate of the 2010 New Strategic Arms Reduction Treaty is unclear. In the unlikely case that the sides are prepared to go beyond New START, there are ways to address further reductions and related issues. A collapse of the arms control regime, on the other hand, would mean the end of constraints on U.S. and Russian nuclear forces, a significant loss of transparency, and potential costs to U.S. security.

  9. ¿A qué juega barbie? obligatoria y heterosexualidad agencia cultural

    OpenAIRE

    Maria Teresa Garzón M

    2011-01-01

    A través del examen de una experiencia de agencia cultural, este artículo de reflexión aborda el concepto de heterosexualidad obligatoria, o heteronormatividad, y lo concibe como un sistema político que tiene impacto en la vida de las mujeres, al constreñirlas en una forma dicotómica de existir, relacionarse y definirse. Se estima que gracias a la agencia cultural es posible cuestionar ese sistema político —logrando un impacto en el mundo de lo simbólico y lo imaginario que lo convierte en he...

  10. Agencia de autocuidado y adherencia al tratamiento en personas con factores de riesgo cardiovascular

    OpenAIRE

    Velandia-Arias, Anita; Rivera-Álvarez, Luz N.

    2013-01-01

    Objetivo Se determino la relación existente entre la Agencia de autocuidado con la adherencia al tratamiento farmacológico y no farmacológico  en pacientes con algún factor de riesgo cardiovascular del programa de crónicos del  hospital Tunjuelito.  Métodos Diseño descriptivo correlacional que midió y relacionó la Agencia de autocuidado y la Adherencia a los tratamientos en una muestra de 201 personas que contaban con algún factor de riesgo cardiovascular: Obesidad, Sedentarismo, Hipertensión...

  11. El turismo, la discapacidad y el rol de las agencias de viaje

    OpenAIRE

    Banegas, Clara Rosario

    2016-01-01

    El presente trabajo de tesis aborda un estudio sobre la situación actual del turismo, la discapacidad y el Rol de las Agencias de Viajes de la ciudad de La Plata, teniendo como objetivo general conocer y analizar la oferta turística de productos y servicios especiales actuales de las Agencias de Viajes en relación a las personas con Discapacidad. Para ello se desarrolla una metodología cuanti y cualitiva a través del análisis y revisión bibliográfica combinada con la realización de entrevi...

  12. METHOD AND APPARATUS FOR CONTROL OF A NUCLEAR REACTOR

    Science.gov (United States)

    Cawley, W.E.

    1962-12-11

    A method and apparatus are described for controlling an overmoderated nuclear reactor containing columns of fuel elements aligned in a plurality of coolant tubes in a stream of coolant water. The invention includes means for adjusting the distance between halves of the fuel element column to vary the relative proportion of fuel and moderator at the center of the reactor. (AEC)

  13. Nuclear polyhedrosis virus as biological control agent of Spodoptera exigua

    NARCIS (Netherlands)

    Smits, P.H.

    1987-01-01

    Several aspects of the control of the beet armyworm, Spodopteraexigua (Hübner) (Lepidoptera: Noctuidae) in greenhouse crops with nuclear polyhedrosis viruses (NPVs) (Baculoviridae, subgroup A) were studied.

    Beet armyworm behaviour was observed in various

  14. Radioactive Iodine and Krypton Control for Nuclear Fuel Reprocessing Facilities

    OpenAIRE

    Nick R. Soelberg; Troy G. Garn; Mitchell R. Greenhalgh; Jack D. Law; Robert Jubin; Denis M. Strachan; Praveen K. Thallapally

    2013-01-01

    The removal of volatile radionuclides generated during used nuclear fuel reprocessing in the US is almost certain to be necessary for the licensing of a reprocessing facility in the US. Various control technologies have been developed, tested, or used over the past 50 years for control of volatile radionuclide emissions from used fuel reprocessing plants. The US DOE has sponsored, since 2009, an Off-gas Sigma Team to perform research and development focused on the most pressing volatile radio...

  15. Control of nuclear β-dystroglycan content is crucial for the maintenance of nuclear envelope integrity and function.

    Science.gov (United States)

    Vélez-Aguilera, Griselda; de Dios Gómez-López, Juan; Jiménez-Gutiérrez, Guadalupe E; Vásquez-Limeta, Alejandra; Laredo-Cisneros, Marco S; Gómez, Pablo; Winder, Steve J; Cisneros, Bulmaro

    2018-02-01

    β-Dystroglycan (β-DG) is a plasma membrane protein that has ability to target to the nuclear envelope (NE) to maintain nuclear architecture. Nevertheless, mechanisms controlling β-DG nuclear localization and the physiological consequences of a failure of trafficking are largely unknown. We show that β-DG has a nuclear export pathway in myoblasts that depends on the recognition of a nuclear export signal located in its transmembrane domain, by CRM1. Remarkably, NES mutations forced β-DG nuclear accumulation resulting in mislocalization and decreased levels of emerin and lamin B1 and disruption of various nuclear processes in which emerin (centrosome-nucleus linkage and β-catenin transcriptional activity) and lamin B1 (cell cycle progression and nucleoli structure) are critically involved. In addition to nuclear export, the lifespan of nuclear β-DG is restricted by its nuclear proteasomal degradation. Collectively our data show that control of nuclear β-DG content by the combination of CRM1 nuclear export and nuclear proteasome pathways is physiologically relevant to preserve proper NE structure and activity. Copyright © 2017 Elsevier B.V. All rights reserved.

  16. Next Generation Nuclear Plant Resilient Control System Functional Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Lynne M. Stevens

    2010-07-01

    Control Systems and their associated instrumentation must meet reliability, availability, maintainability, and resiliency criteria in order for high temperature gas-cooled reactors (HTGRs) to be economically competitive. Research, perhaps requiring several years, may be needed to develop control systems to support plant availability and resiliency. This report functionally analyzes the gaps between traditional and resilient control systems as applicable to HTGRs, which includes the Next Generation Nuclear Plant; defines resilient controls; assesses the current state of both traditional and resilient control systems; and documents the functional gaps existing between these two controls approaches as applicable to HTGRs. This report supports the development of an overall strategy for applying resilient controls to HTGRs by showing that control systems with adequate levels of resilience perform at higher levels, respond more quickly to disturbances, increase operational efficiency, and increase public protection.

  17. Nuclear envelope breakdown is under nuclear not cytoplasmic control in sea urchin zygotes

    OpenAIRE

    1995-01-01

    Nuclear envelope breakdown (NEB) and entry into mitosis are though to be driven by the activation of the p34cdc2-cyclin B kinase complex or mitosis promoting factor (MPF). Checkpoint control mechanisms that monitor essential preparatory events for mitosis, such as DNA replication, are thought to prevent entry into mitosis by downregulating MPF activation until these events are completed. Thus, we were surprised to find that when pronuclear fusion in sea urchin zygotes is blocked with Colcemid...

  18. The first two patients with dura mater associated Creutzfeldt-Jakob disease in the Netherlands

    NARCIS (Netherlands)

    Croes, E. A.; Jansen, G. H.; Lemstra, A. W.; Frijns, C. J.; van Gool, W. A.; van Duijn, C. M.

    2001-01-01

    Creutzfeldt-Jakob disease (CJD) can be transmitted through human growth hormone or gonadotrophin administration, dura mater or cornea transplantation, depth EEG monitoring and the use of contaminated neurosurgical instruments. We describe the first two dura mater associated CJD cases in the

  19. Liver phantom for quality control and training in nuclear medicine

    Science.gov (United States)

    Lima Ferreira, Fernanda Carla; Souza, Divanizia do Nascimento

    2011-10-01

    In nuclear medicine, liver scintigraphy aims to verify organ function based on the radionuclide concentration in the liver and bile flow and is also used to detect tumors. Therefore it is necessary to perform quality control tests in the gamma camera before running the exam to prevent false results. Quality control tests of the gamma camera should thus be performed before running the exam to prevent false results. Such tests generally use radioactive material inside phantoms for evaluation of gamma camera parameters in quality control procedures. Phantoms can also be useful for training doctors and technicians in nuclear medicine procedures. The phantom proposed here has artifacts that simulate nodules; it may take on different quantities, locations and sizes and it may also be mounted without the introduction of nodules. Thus, its images may show hot or cold nodules or no nodules. The phantom consists of acrylic plates hollowed out in the centre, with the geometry of an adult liver. Images for analyses of simulated liver scintigraphy were obtained with the detector device at 5 cm from the anterior surface of the phantom. These simulations showed that this object is suitable for quality control in nuclear medicine because it was possible to visualize artifacts larger than 7.9 mm using a 256×256 matrix and 1000 kcpm. The phantom constructed in this work will also be useful for training practitioners and technicians in order to prevent patients from repeat testing caused by error during examinations.

  20. Patenting the bomb: nuclear weapons, intellectual property, and technological control.

    Science.gov (United States)

    Wellerstein, Alex

    2008-03-01

    During the course of the Manhattan Project, the U.S. government secretly attempted to acquire a monopoly on the patent rights for inventions used in the production of nuclear weapons and nuclear energy. The use of patents as a system of control, while common for more mundane technologies, would seem at first glance to conflict with the regimes of secrecy that have traditionally been associated with nuclear weapons. In explaining the origins and operations of the Manhattan Project patent system, though, this essay argues that the utilization of patents was an ad hoc attempt at legal control of the atomic bomb by Manhattan Project administrators, focused on the monopolistic aspects of the patent system and preexisting patent secrecy legislation. From the present perspective, using patents as a method of control for such weapons seems inadequate, if not unnecessary; but at the time, when the bomb was a new and essentially unregulated technology, patents played an important role in the thinking of project administrators concerned with meaningful postwar control of the bomb.

  1. Nonlinear Control of Hydraulic Manipulator for Decommissioning Nuclear Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Myoung-Ho; Lee, Sung-Uk; Kim, Chang-Hoi; Choi, Byung-Seon; Moon, Jei-Kwon [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2016-10-15

    Robot technique is need to decommission nuclear reactor because of high radiation environment. Especially, Manipulator systems are useful for dismantling complex structure in a nuclear facility. In addition, Hydraulic system is applied to handle heavy duty object. Since hydraulic system can demonstrate high power. The manipulator with hydraulic power is already developed. To solve this problem, various nonlinear control method includes acceleration control. But, it is difficult because acceleration value is highly noisy. In this paper, the nonlinear control algorithm without acceleration control is studied. To verify, the hydraulic manipulator model had been developed. Furthermore, the numerical simulation is carried out. The nonlinear control without acceleration parameter method is developed for hydraulic manipulator. To verify control algorithm, the manipulator is modeled by MBD and the hydraulic servo system is also derived. In addition, the numerical simulation is also carried out. Especially, PID gain is determined though TDC algorithm. In the result of numerical simulation, tracking performance is good without acceleration control. Thus, the PID though TDC with SMC is good for hydraulic manipulator control.

  2. Quality indexes for selecting control materials of the nuclear reactors

    Energy Technology Data Exchange (ETDEWEB)

    Martinez-Val, J.M.; Pena, J.; Esteban Naudin, A.

    1981-01-01

    Quality indexes are established and valued for selecting control materials, The requirements for accomplishing such purposes are explained with detailed analysis: absortion cross section must be as high as possible, adequate reactivity evolution versus depletion, good resistance to radiation, appropiate thermal stability, mechanical resistance and ductility, chemical compatibility with the environment, good heat transfer properties, abundant in the nature and low costs. At present Westinghouse desire to commercialize hafnium as control material shows the exciting task of looking for new materials controlling nuclear reactors.

  3. Comportamientos y capacidad de agencia de autocuidado de adultos con insuficiencia cardiaca

    Directory of Open Access Journals (Sweden)

    EDITH ARREDONDO HOLGUÍN

    2010-06-01

    Full Text Available Este estudio tiene como objetivo describir comportamientos y capacidad de agencia de autocuidado de pacientes con insuficiencia cardiaca de una clínica cardiovascular de Medellín entre noviembre de 2007 y mayo de 2008. Es un estudio descriptivo con abordaje cuantitativo. La muestra fue de 206 adultos con insuficiencia cardiaca diagnosticados por sintomatología clínica, fracción de eyección menor o igual a 40%. Se usaron para la recolección de datos la Escala Capacidad de Agencia de Autocuidado desarrollada por Isemberg y Evers et ál. (1993, traducida por Gallego, que mide el nivel de agencia de autocuidado, y la Escala Comportamientos de Autocuidado validada en Colombia en 2007 por Arredondo, que mide la frecuencia de comportamientos de autocuidado de adultos con insuficiencia cardiaca en la solicitud de ayuda, adaptación a vivir con la enfermedad y el régimen terapéutico, modificación del autoconcepto y aceptación de sí mismo, vivir con efectos de la insuficiencia cardiaca y el tratamiento. Concluye que el mayor número de pacientes eran hombres; que factores básicos condicionantes como el apoyo de la familia, desempeño de un trabajo, afiliación al sistema de salud, nivel socioeconómico y acceso a un nivel educativo fueron importantes para los pacientes. La frecuencia de comportamientos de autocuidado fue media en los adultos en la mayoría de las dimensiones y el nivel de agencia fue alto y muy alto. Igualmente se concluyó que no hay una correlación entre agencia y comportamientos de autocuidado. Lo que plantea que los adultos tienen el conocimiento pero no han tomado la decisión de realizar acciones de autocuidado.

  4. Universal quantum control in zero-field nuclear magnetic resonance

    Science.gov (United States)

    Bian, Ji; Jiang, Min; Cui, Jiangyu; Liu, Xiaomei; Chen, Botao; Ji, Yunlan; Zhang, Bo; Blanchard, John; Peng, Xinhua; Du, Jiangfeng

    2017-05-01

    This paper describes a general method for the manipulation of nuclear spins in zero magnetic field. In the absence of magnetic fields, the spins lose the individual information on chemical shifts and inequivalent spins can only be distinguished by nuclear gyromagnetic ratios and spin-spin couplings. For spin-1/2 nuclei with different gyromagnetic ratios (i.e., different species) in zero magnetic field, we describe the scheme to realize a set of universal quantum logic gates, e.g., arbitrary single-qubit gates and a two-qubit controlled-not gate. This method allows for universal quantum control in systems which might provide promising applications in materials science, chemistry, biology, quantum information processing, and fundamental physics.

  5. La escuela media en su límite. Diferencias y continuidades en las configuraciones nacionales de la región: los casos de Brasil, Argentina y Chile: différences et continuités des configurations nationales dans la région: les cas du Brésil, de l'Argentine et du Chili

    Directory of Open Access Journals (Sweden)

    Guillermina Tiramonti

    2011-09-01

    Full Text Available El artículo se refiere a la exigencia de universalización del nivel medio que pende sobre los distintos países de la región, reconstruye los discursos que fundamentan y legitiman estas demandas. El texto muestra la expansión del nivel, las modificaciones que las distintas reformas han introducido y marca las invariancias de un formato escolar que se mantiene desde su creación a fines del siglo XIX. Analiza las diferentes configuraciones nacionales de la educación media con referencia a tres países; Brasil, Argentina y Chile y marca la continuidad de las estrategias de inclusión con segregación y la funcionalidad de la expansión con las exigencias del mercado y del orden político.

  6. Development of Computer-Aided Learning Programs on Nuclear Nonproliferation and Control

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Hyun Chul [Korea Institute of Nuclear Nonproliferation and Control, Daejeon (Korea, Republic of)

    2011-10-15

    The fulfillment of international norms for nuclear nonproliferation is indispensable to the promotion of nuclear energy. The education and training for personnel and mangers related to the nuclear material are one of crucial factors to avoid unintended non-compliance to international norms. Korea Institute of Nuclear Nonproliferation and Control (KINAC) has been providing education and training on nuclear control as its legal duty. One of the legally mandatory educations is 'nuclear control education' performed since 2006 for the observation of the international norms on nuclear nonproliferation and the spread of the nuclear control culture. The other is 'physical protection education' performed since 2010 for maintaining the national physical protection regime effectively and the spread of the nuclear security culture. The 2010 Nuclear Security Summit was held in Washington, DC to enhance international cooperation to prevent nuclear terrorism. During the Summit, the South Korea was chosen to host the second Nuclear Summit in 2012. South Korean President announced that South Korea would share its expertise and support the Summit's mission by setting up an international education and training center on nuclear security in 2014. KINAC is making a full effort to set up the center successfully. An important function of the center is education and training in the subjects of nuclear nonproliferation, nuclear safeguards, nuclear security, and nuclear export/import control. With increasing importance of education and training education on nuclear nonproliferation and control, KINAC has been developing computer-aided learning programs on nuclear nonproliferation and control to overcome the weaknesses in classroom educations. This paper shows two learning programs. One is an e-learning system on the nuclear nonproliferation and control and the other is a virtual reality program for training nuclear material accountancy inspection of light water

  7. Ergonomics in the licensing and evaluation of nuclear reactors control room; A ergonomia no licenciamento e na avaliacao de salas de controle de reatores nucleares

    Energy Technology Data Exchange (ETDEWEB)

    Santos, Isaac Jose Antonio Luquetti dos [Instituto de Engenharia Nuclear (IEN), Rio de Janeiro, RJ (Brazil); Vidal, Mario Cesar Rodriguez [Universidade Federal, Rio de Janeiro, RJ (Brazil). Coordenacao dos Programas de Pos-graduacao de Engenharia. Programa de Engenharia de Producao

    2002-07-01

    A nuclear control room is a complex system that controls a thermodynamic process used to produce electrical energy. The operators interact with the control room through interfaces that have significant implications to nuclear plant safety and influence the operator activity. The TMI (Three Mile Island) accident demonstrated that only the anthropometric aspects were not enough for an adequate nuclear control room design. The studies showed that the accident was aggravated because the designers had not considered adequately human factor aspects. After TMI accident, the designers introduce in the nuclear control room development only human factors standards and human factors guidelines. The ergonomics approaches was not considered. Our objective is introduce in nuclear control room design and nuclear control room evaluation, a methodology that. includes human factors standards, human factors guidelines and ergonomic approaches, the operator activity analysis. (author)

  8. Nuclear Ras2-GTP controls invasive growth in Saccharomyces cerevisiae.

    Science.gov (United States)

    Broggi, Serena; Martegani, Enzo; Colombo, Sonia

    2013-01-01

    Using an eGFP-RBD3 probe, which specifically binds Ras-GTP, we recently showed that the fluorescent probe was localized to the plasma membrane and to the nucleus in wild type cells growing exponentially on glucose medium, indicating the presence of active Ras in these cellular compartments. To investigate the nuclear function of Ras-GTP, we generated a strain where Ras2 is fused to the nuclear export signal (NES) from the HIV virus, in order to exclude this protein from the nucleus. Our results show that nuclear active Ras2 is required for invasive growth development in haploid yeast, while the expression of the NES-Ras2 protein does not cause growth defects either on fermentable or non-fermentable carbon sources and does not influence protein kinase A (PKA) activity related phenotypes analysed. Moreover, we show that the cAMP/PKA pathway controls invasive growth influencing the localization of active Ras. In particular, we show that PKA activity plays a role in the localization of active Ras and influences the ability of the cells to invade the agar: high PKA activity leads to a predominant nuclear accumulation of active Ras and induces invasive growth, while low PKA activity leads to plasma membrane localization of active Ras and to a defective invasive growth phenotype.

  9. Advanced interaction media in nuclear power plant control rooms.

    Science.gov (United States)

    Stephane, Lucas

    2012-01-01

    The shift from analog to digital Instruments (related mainly to information visualization) and Controls in Nuclear Power Plant Main Control Rooms (NPP MCR) is a central current topic of investigation. In NPP MCR, digitalization was implemented gradually, analog and digital systems still coexisting for the two main systems related to safety--Safety Instruments and Control System (SICS) and Process Instruments and Controls System (PICS). My ongoing research focuses on the introduction of Advanced Interaction Media (AIM) such as stereoscopic 3D visualization and multi-touch surfaces in control rooms. This paper proposes a Safety-Centric approach for gathering the Design Rationale needed in the specification of such novel AIM concepts as well as their evaluation through user tests. Beyond methodological research, the final output of the current research is to build an experimental simulator aiming to enhance improvements in Human-Systems Integration (HSI). This paper provides an overview of the topics under consideration.

  10. Nuclear Technology Series. Course 6: Instrumentation and Control of Reactors and Plant Systems.

    Science.gov (United States)

    Center for Occupational Research and Development, Inc., Waco, TX.

    This technical specialty course is one of thirty-five courses designed for use by two-year postsecondary institutions in five nuclear technician curriculum areas: (1) radiation protection technician, (2) nuclear instrumentation and control technician, (3) nuclear materials processing technician, (4) nuclear quality-assurance/quality-control…

  11. Defense Nuclear Facilities Safety Board: Improvements Needed to Strengthen Internal Control and Promote Transparency

    Science.gov (United States)

    2015-01-01

    of nuclear weapons, disposal of nuclear waste and components, and decommissioning and cleanup of facilities once they are no longer needed.1 These...design, construction, operation, and decommissioning of DOE defense nuclear facilities ; (2) investigating any event or practice at these facilities that...DEFENSE NUCLEAR FACILITIES SAFETY BOARD Improvements Needed to Strengthen Internal Control and Promote

  12. Nuclear envelope breakdown is under nuclear not cytoplasmic control in sea urchin zygotes.

    Science.gov (United States)

    Sluder, G; Thompson, E A; Rieder, C L; Miller, F J

    1995-06-01

    Nuclear envelope breakdown (NEB) and entry into mitosis are though to be driven by the activation of the p34cdc2-cyclin B kinase complex or mitosis promoting factor (MPF). Checkpoint control mechanisms that monitor essential preparatory events for mitosis, such as DNA replication, are thought to prevent entry into mitosis by downregulating MPF activation until these events are completed. Thus, we were surprised to find that when pronuclear fusion in sea urchin zygotes is blocked with Colcemid, the female pronucleus consistently breaks down before the male pronucleus. This is not due to regional differences in the time of MPF activation, because pronuclei touching each other break down asynchronously to the same extent. To test whether NEB is controlled at the nuclear or cytoplasmic level, we activated the checkpoint for the completion of DNA synthesis separately in female and male pronuclei by treating either eggs or sperm before fertilization with psoralen to covalently cross-link base-paired strands of DNA. When only the maternal DNA is cross-linked, the male pronucleus breaks down first. When the sperm DNA is cross-linked, male pronuclear breakdown is substantially delayed relative to female pronuclear breakdown and sometimes does not occur. Inactivation of the Colcemid after female NEB in such zygotes with touching pronuclei yields a functional spindle composed of maternal chromosomes and paternal centrosomes. The intact male pronucleus remains located at one aster throughout mitosis. In other experiments, when psoralen-treated sperm nuclei, over 90% of the zygote nuclei do not break down for at least 2 h after the controls even though H1 histone kinase activity gradually rises close to, or higher than, control mitotic levels. The same is true for normal zygotes treated with aphidicolin to block DNA synthesis. From these results, we conclude that NEB in sea urchin zygotes is controlled at the nuclear, not cytoplasmic, level, and that mitotic levels of

  13. The evolution of legal approaches to controlling nuclear and radiological weapons and combating the threat of nuclear terrorism

    NARCIS (Netherlands)

    Herbach, J.

    2015-01-01

    This chapter traces the evolution of international law related to the weaponization of nuclear and other radioactive materials, focusing in particular on the law pertaining to preventing acts of nuclear terrorism. International efforts to control atomic energy have evolved substantially since the

  14. Interacción social y agencia en la disposición cultural universitaria

    Directory of Open Access Journals (Sweden)

    Rosa Mirian Caamaño Zambrano

    2017-07-01

    Full Text Available El objetivo del artículo es revelar sistemas de acciones en la enseñanza e investigación, sustentado en habilidades culturales. Para la estrategia metodológica se realizó la revisión bibliográfica de la interacción social basada en la observación de la comunidad universitaria. El resultado conduce a la teoría de la agencia, promoción y orientación de la acción en la sociedad, con desafíos al aprendizaje desde un rol comprensivo de los profesores. Se propone reflexionar acerca de la importancia y vías de la agencia cultural universitaria, los impactos que el proceso extensionista produce en la interacción social, y los efectos que provoca sobre los objetivos curriculares.

  15. ¿A qué juega barbie? obligatoria y heterosexualidad agencia cultural

    Directory of Open Access Journals (Sweden)

    Maria Teresa Garzón M

    2011-09-01

    Full Text Available A través del examen de una experiencia de agencia cultural, este artículo de reflexión aborda el concepto de heterosexualidad obligatoria, o heteronormatividad, y lo concibe como un sistema político que tiene impacto en la vida de las mujeres, al constreñirlas en una forma dicotómica de existir, relacionarse y definirse. Se estima que gracias a la agencia cultural es posible cuestionar ese sistema político —logrando un impacto en el mundo de lo simbólico y lo imaginario que lo convierte en hegemónico— y contribuir a su desmonte.

  16. BENCHMARKING INTERNO EN UNA CENTRAL DE COMPRAS DE AGENCIAS DE VIAJES

    Directory of Open Access Journals (Sweden)

    Isabel Montero Muradas

    2010-01-01

    Full Text Available El sector turístico es uno de los más dinámicos de nuestra economía que necesita poner en marcha nuevas estrategias para mantener sus niveles de participación en el PIB. El objetivo de este trabajo es determinar, mediante un análisis conjunto probabilístico, utilizando el modelo de Rasch, la importancia relativa de los factores determinantes de la oferta turística de una alianza estratégica entre agencias de viajes: Travel Advisors Guild (TAG. En los resultados se destaca el posicionamiento de las agencias integradas en el TAG, así como los desajustes competitivos internos.

  17. El papel de las agencias de seguros en la competencia entre compañías aseguradoras

    Directory of Open Access Journals (Sweden)

    Leonardo Medrano

    2008-01-01

    Full Text Available Este artículo estudia el mercado de seguros cuando las compañías aseguradoras (aseguradoras venden sus pólizas por medio de agencias de seguros (agencias o agentes. Analiza los efectos de las comisiones por ventas pagadas a las agencias en las primas de seguros y en el bienestar del consumidor. Se considera el comportamiento oportunista de las agencias al vender las pólizas emitidas por la aseguradora que le ofrece la comisión mas alta. Se consideran también diferentes estructuras de mercado: un duopolio de aseguradoras que compiten en comisiones (competencia entre aseguradoras, la colusión entre aseguradoras con las agencias manteniendose independientes (colusión horizontal o monopolio de aseguradoras y la colusión entre aseguradoras y agencias (integración vertical o agentes exclusivos. Mostramos que la competencia entre aseguradoras y la integración vertical generan primas más altas que la colusión horizontal. Además, mostramos que la comisión óptima desde del punto de vista del consumidor pueda ser mayor que la comisión generada por cualquiera de las tres estructuras de mercado antes señaladas

  18. Controlling Androgen receptor nuclear localization by dendrimer conjugates

    Science.gov (United States)

    Wang, Haoyu

    Androgen Receptor (AR) antagonists, such as bicalutamide and flutamide have been used widely in the treatment of prostate cancer. Although initial treatment is effective, prostate cancer cells often acquire antiandrogen resistance with prolonged treatment. AR over-expression and AR mutations contribute to the development of antiandrogen resistant cancer. Second generation antiandrogens such as enzalutamide are more effective and show reduced AR nuclear localization. In this study, derivatives of PAN52, a small molecule antiandrogen previously developed in our lab, were conjugated to the surface of generation 4 and generation 6 PAMAM dendrimers to obtain antiandrogen PAMAM dendrimer conjugates (APDC). APDCs readily enter cells and associate with AR in the cytoplasm. Due to their large size and positive charge, they can not enter the nucleus, thus retaining AR in the cytoplasm. In addition, APDCs are effective in decreasing AR mediated transcription and cell proliferation. APDC is the first AR antagonists that inhibit DHT-induced nuclear localization of AR. By inhibiting AR nuclear localization, APDC represents a new class of antiandrogens that offer an alternative approach to addressing antiandrogen-resistant prostate cancer. Lysine post-translational modification of AR Nuclear Localization Sequence (NLS) has great impact on AR cellular localization. It is of interest to understand which modifications modulate AR translocation into the nucleus. In this study, we prepared dendrimer-based acetyltransferase mimetic (DATM), DATM is able to catalytically acetylate AR in CWR22Rv1 cells, which will be a useful tool for studying AR modification effect on AR cellular localization. Derivatives of DATM, which transfer other chemical groups to AR, can be prepared similarly, and with more dendrimer based AR modification tools prepared in future, we will be able to understand and control AR cellular localization through AR modification.

  19. Fuzzy control applied to nuclear power plant pressurizer system

    Energy Technology Data Exchange (ETDEWEB)

    Oliveira, Mauro V.; Almeida, Jose C.S., E-mail: mvitor@ien.gov.b, E-mail: jcsa@ien.gov.b [Instituto de Engenharia Nuclear (IEN/CNEN-RJ), Rio de Janeiro, RJ (Brazil)

    2011-07-01

    In a pressurized water reactor (PWR) nuclear power plants (NPPs) the pressure control in the primary loop is very important for keeping the reactor in a safety condition and improve the generation process efficiency. The main component responsible for this task is the pressurizer. The pressurizer pressure control system (PPCS) utilizes heaters and spray valves to maintain the pressure within an operating band during steady state conditions, and limits the pressure changes, during transient conditions. Relief and safety valves provide overpressure protection for the reactor coolant system (RCS) to ensure system integrity. Various protective reactor trips are generated if the system parameters exceed safe bounds. Historically, a proportional-integral derivative (PID) controller is used in PWRs to keep the pressure in the set point, during those operation conditions. The purpose of this study has two main goals: first is to develop a pressurizer model based on artificial neural networks (ANNs); second is to develop a fuzzy controller for the PWR pressurizer pressure, and compare its performance with the P controller. Data from a simulator PWR plant was used to test the ANN and the controllers as well. The reference simulator is a Westinghouse 3-loop PWR plant with a total thermal output of 2785 MWth. The simulation results show that the pressurizer ANN model response are in reasonable agreement with the simulated power plant, and the fuzzy controller built in this study has better performance compared to the P controller. (author)

  20. A Balance between Nuclear and Cytoplasmic Volumes Controls Spindle Length

    Science.gov (United States)

    Novakova, Lucia; Kovacovicova, Kristina; Dang-Nguyen, Thanh Quang; Sodek, Martin; Skultety, Michal; Anger, Martin

    2016-01-01

    Proper assembly of the spindle apparatus is crucially important for faithful chromosome segregation during anaphase. Thanks to the effort over the last decades, we have very detailed information about many events leading to spindle assembly and chromosome segregation, however we still do not understand certain aspects, including, for example, spindle length control. When tight regulation of spindle size is lost, chromosome segregation errors emerge. Currently, there are several hypotheses trying to explain the molecular mechanism of spindle length control. The number of kinetochores, activity of molecular rulers, intracellular gradients, cell size, limiting spindle components, and the balance of the spindle forces seem to contribute to spindle size regulation, however some of these mechanisms are likely specific to a particular cell type. In search for a general regulatory mechanism, in our study we focused on the role of cell size and nuclear to cytoplasmic ratio in this process. To this end, we used relatively large cells isolated from 2-cell mouse embryos. Our results showed that the spindle size upper limit is not reached in these cells and suggest that accurate control of spindle length requires balanced ratio between nuclear and cytoplasmic volumes. PMID:26886125

  1. Cranial Reconstruction following the Removal of an Infected Synthetic Dura Mater Substitute

    Directory of Open Access Journals (Sweden)

    Nobutaka Yoshioka, MD

    2014-04-01

    Conclusions: Staged cranial reconstruction after the removal of an infected synthetic dura mater substitute using an algorithmic approach is feasible and safe, produces satisfactory cosmetic results, and is not associated with any complications.

  2. Evidence for CGRP re‐uptake in rat dura mater encephali

    National Research Council Canada - National Science Library

    Gupta, Saurabh; Amrutkar, Dipak Vasantrao; Mataji, Aydin; Salmasi, Hassan; Hay‐Schmidt, Anders; Sheykhzade, Majid; Messlinger, Karl; Olesen, Jes; Jansen‐Olesen, Inger

    2010-01-01

    BACKGROUND AND PURPOSE Calcitonin gene‐related peptide (CGRP) is widely distributed in the trigeminovascular system and released from sensory fibres of the cranial dura mater upon noxious stimulation...

  3. Local mechanical anisotropy in human cranial dura mater allografts.

    Science.gov (United States)

    Sacks, M S; Jimenez Hamann, M C; Otaño-Lata, S E; Malinin, T I

    1998-08-01

    Human cranial dura mater (CDM) allograft's success as a repair biomaterial is partly due to its high mechanical strength, which facilitates its ability to form water-tight barriers and resist high in-vivo mechanical loads. Previous studies on CDM allograft mechanical behavior used large test specimens and concluded that the allograft was mechanically isotropic. However, we have quantified CDM microstructure using small angle light scattering (SALS) and found regions of well-aligned fibers displaying structural symmetry between the right and left halves (Jimenez et al., 1998). The high degree of fiber alignment in these regions suggests that they are mechanically anisotropic. However, identification of these regions using SALS requires irreversible tissue dehydration, which may affect mechanical properties. Instead, we utilized CDM structural symmetry to estimate the fiber architecture of one half of the CDM using computer graphics to flip the SALS fiber architecture map of the corresponding half about the plane of symmetry. Test specimens (20 mm x 4 mm) were selected parallel and perpendicular to the preferred fiber directions and subjected to uniaxial mechanical failure testing. CDM allografts were found to be locally anisotropic, having an ultimate tensile strength (UTS) parallel to the fibers of 12.76 +/- 1.65 MPa, and perpendicular to the fibers of 5.21 +/- 1.01 MPa (mean +/- sem). These results indicate that uniaxial mechanical tests on large samples used in previous studies tended to mask the local anisotropic nature of the smaller constituent sections. The testing methods established in this study can be used in the evaluation of new CDM processing methods and post-implant allograft mechanical integrity.

  4. Radioactive Iodine and Krypton Control for Nuclear Fuel Reprocessing Facilities

    Energy Technology Data Exchange (ETDEWEB)

    Soelberg, Nick R. [Idaho National Laboratory, Idaho Falls, ID 83415, USA; Garn, Troy G. [Idaho National Laboratory, Idaho Falls, ID 83415, USA; Greenhalgh, Mitchell R. [Idaho National Laboratory, Idaho Falls, ID 83415, USA; Law, Jack D. [Idaho National Laboratory, Idaho Falls, ID 83415, USA; Jubin, Robert [Oak Ridge National Laboratory, Oak Ridge, TN 37831, USA; Strachan, Denis M. [Pacific Northwest National Laboratory, Richland, WA 99252, USA; Thallapally, Praveen K. [Pacific Northwest National Laboratory, Richland, WA 99252, USA

    2013-01-01

    The removal of volatile radionuclides generated during used nuclear fuel reprocessing in the US is almost certain to be necessary for the licensing of a reprocessing facility in the US. Various control technologies have been developed, tested, or used over the past 50 years for control of volatile radionuclide emissions from used fuel reprocessing plants. The US DOE has sponsored, since 2009, an Off-gas Sigma Team to perform research and development focused on the most pressing volatile radionuclide control and immobilization problems. In this paper, we focus on the control requirements and methodologies for85Kr and129I. Numerous candidate technologies have been studied and developed at laboratory and pilot-plant scales in an effort to meet the need for high iodine control efficiency and to advance alternatives to cryogenic separations for krypton control. Several of these show promising results. Iodine decontamination factors as high as 105, iodine loading capacities, and other adsorption parameters including adsorption rates have been demonstrated under some conditions for both silver zeolite (AgZ) and Ag-functionalized aerogel. Sorbents, including an engineered form of AgZ and selected metal organic framework materials (MOFs), have been successfully demonstrated to capture Kr and Xe without the need for separations at cryogenic temperatures.

  5. Radioactive Iodine and Krypton Control for Nuclear Fuel Reprocessing Facilities

    Directory of Open Access Journals (Sweden)

    Nick R. Soelberg

    2013-01-01

    Full Text Available The removal of volatile radionuclides generated during used nuclear fuel reprocessing in the US is almost certain to be necessary for the licensing of a reprocessing facility in the US. Various control technologies have been developed, tested, or used over the past 50 years for control of volatile radionuclide emissions from used fuel reprocessing plants. The US DOE has sponsored, since 2009, an Off-gas Sigma Team to perform research and development focused on the most pressing volatile radionuclide control and immobilization problems. In this paper, we focus on the control requirements and methodologies for 85Kr and 129I. Numerous candidate technologies have been studied and developed at laboratory and pilot-plant scales in an effort to meet the need for high iodine control efficiency and to advance alternatives to cryogenic separations for krypton control. Several of these show promising results. Iodine decontamination factors as high as 105, iodine loading capacities, and other adsorption parameters including adsorption rates have been demonstrated under some conditions for both silver zeolite (AgZ and Ag-functionalized aerogel. Sorbents, including an engineered form of AgZ and selected metal organic framework materials (MOFs, have been successfully demonstrated to capture Kr and Xe without the need for separations at cryogenic temperatures.

  6. An expert display system and nuclear power plant control rooms

    Science.gov (United States)

    Beltracchi, L.

    1988-04-01

    General topics for consideration when designing expert display systems and nuclear power plant control room displays are summarized. A system is proposed in which the display of segments (a combined series of graphic primitives or a reusable collection of graphic primitives and primitives attributes stored in memory) controls a cathode-ray-tube's screen to form an image of plant operations. The image consists of an icon of: (1) the process (heat engine cycle), (2) plant control systems, and (3) safety systems. A set of data-driven, forward-chaining computer-stored rules control the display segments. As plant operation changes, measured plant data are processed through the rules, and the results control the deletion and addition of segments to the display format. The icon contains information needed by control rooms operators to monitor plant operations. One example of an expert display is illustrated for the operator's task of monitoring leakage from a safety valve in a steam line of a boiling water reactor (BWR). In another example, the use of an expert display to monitor plant operations during pre-trip, trip, and post-trip operations is discussed as a universal display.

  7. La agencia de medios en el nuevo escenario comunicativo / Media agency in the new communicative scenario

    Directory of Open Access Journals (Sweden)

    Araceli Castelló Martínez

    2014-12-01

    Full Text Available La industria comunicativa vive un periodo de cambios profundos a los que la agencia de medios, uno de los actores principales en el mercado publicitario, no ha permanecido ajena. La transmedialidad de los contenidos, los nuevos formatos publicitarios en los diferentes medios, el engagement que demanda el anunciante o el fomento de la experiencia del usuario, entre otros aspectos, han revolucionado la definición de las estrategias de medios. Los objetivos del presente artículo pasan por analizar el papel actual de la agencia de medios en el mercado publicitario y estudiar las características de las estrategias de medios en el presente contexto comunicativo así como su integración en las estrategias de comunicación. La metodología se basa en una revisión bibliográfica de publicaciones dedicadas a la planificación publicitaria y la agencia de medios en base a una serie de palabras clave y en un análisis de los servicios que ofrecen las agencias de medios en sus páginas web. Los resultados destacan el papel estratégico que ha adquirido la agencia de medios en el actual escenario comunicativo, por una parte, y la integración y la transmedialidad que caracterizan hoy en día a las estrategias de medios, por otra. Abstract Communication industry lives a period of profound changes that the media agency, one of the key players in the advertising market, has not remained apart from. Transmediality of contents, new advertising formats in the various media, the engagement that advertisers demand or the encouragement of the users experience, among others, have revolutionized the definition of media strategies.The goals of the present article focus on analyzing the current role of the media agency in the advertising market and studying the characteristics of media strategies in the present communicative context as well as their integration in communication strategies. The methodology is based on a literature review of publications devoted to

  8. Information Foraging in Nuclear Power Plant Control Rooms

    Energy Technology Data Exchange (ETDEWEB)

    R.L. Boring

    2011-09-01

    nformation foraging theory articulates the role of the human as an 'informavore' that seeks information and follows optimal foraging strategies (i.e., the 'information scent') to find meaningful information. This paper briefly reviews the findings from information foraging theory outside the nuclear domain and then discusses the types of information foraging strategies operators employ for normal and off-normal operations in the control room. For example, operators may employ a predatory 'wolf' strategy of hunting for information in the face of a plant upset. However, during routine operations, the operators may employ a trapping 'spider' strategy of waiting for relevant indicators to appear. This delineation corresponds to information pull and push strategies, respectively. No studies have been conducted to determine explicitly the characteristics of a control room interface that is optimized for both push and pull information foraging strategies, nor has there been empirical work to validate operator performance when transitioning between push and pull strategies. This paper explores examples of control room operators as wolves vs. spiders and con- cludes by proposing a set of research questions to investigate information foraging in control room settings.

  9. Flammability Control In A Nuclear Waste Vitrification System

    Energy Technology Data Exchange (ETDEWEB)

    Zamecnik, John R.; Choi, Alexander S.; Johnson, Fabienne C.; Miller, Donald H.; Lambert, Daniel P.; Stone, Michael E.; Daniel, William E. Jr.

    2013-07-25

    The Defense Waste Processing Facility at the Savannah River Site processes high-level radioactive waste from the processing of nuclear materials that contains dissolved and precipitated metals and radionuclides. Vitrification of this waste into borosilicate glass for ultimate disposal at a geologic repository involves chemically modifying the waste to make it compatible with the glass melter system. Pretreatment steps include removal of excess aluminum by dissolution and washing, and processing with formic and nitric acids to: 1) adjust the reduction-oxidation (redox) potential in the glass melter to reduce radionuclide volatility and improve melt rate; 2) adjust feed rheology; and 3) reduce by steam stripping the amount of mercury that must be processed in the melter. Elimination of formic acid in pretreatment has been studied to eliminate the production of hydrogen in the pretreatment systems, which requires nuclear grade monitoring equipment. An alternative reductant, glycolic acid, has been studied as a substitute for formic acid. However, in the melter, the potential for greater formation of flammable gases exists with glycolic acid. Melter flammability is difficult to control because flammable mixtures can be formed during surges in offgases that both increase the amount of flammable species and decrease the temperature in the vapor space of the melter. A flammable surge can exceed the 60% of the LFL with no way to mitigate it. Therefore, careful control of the melter feed composition based on scaled melter surge testing is required. The results of engineering scale melter tests with the formic-nitric flowsheet and the use of these data in the melter flammability model are presented.

  10. Quality control in nuclear medicine;Mise en oeuvre du controle de qualite en medecine nucleaire

    Energy Technology Data Exchange (ETDEWEB)

    Voyant, C. [Hopital de Castelluccio, unite de radiophysique, 20 - Ajaccio (France); Universite de Corse, CNRS UMR SPE 6134, 20 - Corte (France)

    2010-03-15

    Like in many nuclear medicine centers, the A.F.S.S.A.P.S. decision of November 25, 2008, has slightly changed our habits. The centers with medical physicist already made most of these controls, and this concept was not new for them. But what about the other centers? Sometimes, measures were made as expected, other times the manufacturers were expected to do them during the maintenance time, often nothing was formalized, and even in some cases nothing was done. Our experience in quality control in nuclear medicine is relatively recent, but we find interesting to raise some issues, including the duration for all these controls, the possible delegations, the means necessary to build them and difficulties in applying these controls. (author)

  11. Understanding Nuclear Weapons and Arms Control: A Guide to the Issues. New Edition.

    Science.gov (United States)

    Mayers, Teena

    Intended for secondary and college level students and teachers, this guide discusses the nuclear arms control issue. There are four sections. Section I discusses U.S. nuclear strategy from 1945 to the present, strategic nuclear weapons competition between the United States and the Union of Soviet Socialist Republics (U.S.S.R.), U.S.…

  12. Controlling the Power Output of a Nuclear Reactor with Fuzzy Logic

    NARCIS (Netherlands)

    Ruan, D.; Wal, A.J. van der

    1997-01-01

    The application of fuzzy logic control (FLC) in the domain of nuclear industry presents a tremendous challenge. The main reason for this is the public awareness of the risks of nuclear reactors and the very strict safety regulations in force for nuclear power plants. The very same regulations

  13. Fault-tolerant adaptive control for load-following in static space nuclear power systems

    Science.gov (United States)

    Parlos, Alexander G.; Onbasioglu, Fetiye O.; Peddicord, Kenneth L.; Metzger, John D.

    1992-01-01

    The possible use of a dual-loop model-based adaptive control system for load following in static space nuclear power systems is investigated. The proposed approach has thus far been applied only to a thermoelectric space nuclear power system but is equally applicable to other static space nuclear power systems such as thermionic systems.

  14. 10 CFR 50.44 - Combustible gas control for nuclear power reactors.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Combustible gas control for nuclear power reactors. 50.44... for nuclear power reactors. (a) Definitions—(1) Inerted atmosphere means a containment atmosphere with... pressurized water nuclear power reactor with an operating license on October 16, 2003, except for those...

  15. Controlling the power output of a nuclear reactor with fuzzy logic

    NARCIS (Netherlands)

    Ruan, D.; Wal, A.J. van der

    1998-01-01

    The application of fuzzy logic control (FLC) in the domain of nuclear industry presents a tremendous challenge. The main reason for this is the public awareness of the risks of nuclear reactors and the very strict safety regulations in force for nuclear power plants. The very same regulations

  16. 10 CFR 1017.8 - Subject areas eligible to be Unclassified Controlled Nuclear Information.

    Science.gov (United States)

    2010-01-01

    ... nuclear weapons or components that were once classified as Restricted Data, as defined in section 11y. of... Nuclear Information. 1017.8 Section 1017.8 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) IDENTIFICATION AND PROTECTION OF UNCLASSIFIED CONTROLLED NUCLEAR INFORMATION Initially Determining What Information...

  17. Database design for Physical Access Control System for nuclear facilities

    Energy Technology Data Exchange (ETDEWEB)

    Sathishkumar, T., E-mail: satishkumart@igcar.gov.in; Rao, G. Prabhakara, E-mail: prg@igcar.gov.in; Arumugam, P., E-mail: aarmu@igcar.gov.in

    2016-08-15

    Highlights: • Database design needs to be optimized and highly efficient for real time operation. • It requires a many-to-many mapping between Employee table and Doors table. • This mapping typically contain thousands of records and redundant data. • Proposed novel database design reduces the redundancy and provides abstraction. • This design is incorporated with the access control system developed in-house. - Abstract: A (Radio Frequency IDentification) RFID cum Biometric based two level Access Control System (ACS) was designed and developed for providing access to vital areas of nuclear facilities. The system has got both hardware [Access controller] and software components [server application, the database and the web client software]. The database design proposed, enables grouping of the employees based on the hierarchy of the organization and the grouping of the doors based on Access Zones (AZ). This design also illustrates the mapping between the Employee Groups (EG) and AZ. By following this approach in database design, a higher level view can be presented to the system administrator abstracting the inner details of the individual entities and doors. This paper describes the novel approach carried out in designing the database of the ACS.

  18. Nonlinear Fuzzy Model Predictive Control for a PWR Nuclear Power Plant

    OpenAIRE

    Liu, Xiangjie; Wang, Mengyue

    2014-01-01

    Reliable power and temperature control in pressurized water reactor (PWR) nuclear power plant is necessary to guarantee high efficiency and plant safety. Since the nuclear plants are quite nonlinear, the paper presents nonlinear fuzzy model predictive control (MPC), by incorporating the realistic constraints, to realize the plant optimization. T-S fuzzy modeling on nuclear power plant is utilized to approximate the nonlinear plant, based on which the nonlinear MPC controller is devised via pa...

  19. Evolution in nuclear strategy in US and Russia and its implications in arms control

    Energy Technology Data Exchange (ETDEWEB)

    Sokov, N

    2003-07-01

    Today, there is a growing tendency in war-fighting scenarios to include limited use of nuclear weapons. New developments in nuclear policy could be attributed to changes in the international situation like the multiplication of low level conflicts and the threat of terrorism. This paper analyzes the evolution of the Russian nuclear doctrine, the transformation of the US nuclear policy and their consequences on arms control. (J.S.)

  20. Capacidad de agencia de autocuidado y factores de riesgo cardiovascular en adolescentes

    OpenAIRE

    Morales Aguilar, Rosa del Socorro

    2013-01-01

    Este estudio tuvo como objetivo determinar la relación entre la capacidad de agencia de autocuidado y los factores de riesgo cardiovascular en adolescentes de una Institución de Educación Superior en el Distrito de Barranquilla. Metodología: Estudio descriptivo, exploratorio, de corte transversal, con abordaje cuantitativo, basado en la teoría del déficit de autocuidado de Orem. La muestra fue de 133 adolescentes, seleccionados mediante muestreo aleatorio simple. Se aplicó la escala ASA, el c...

  1. Los despachos de agencia (teletipos) como tipo documental Agency dispatches (teletypes) as a documentary type

    OpenAIRE

    Jorge Caldera Serrano

    2007-01-01

    Se analiza el despacho de agencia como tipo documental que debe ser conservado y analizado por parte de los departamentos de documentación de los medios de comunicación tanto de prensa escrita como audiovisuales y sonoros. Para llevar a cabo dicho análisis se realiza un estudio sobre su estructura semántica discursiva que sirva como base para la identificación de los puntos de acceso con los que debe contar la base de datos que albergue dicho material: información temática; cronológica, geogr...

  2. Entre crisis, agencia y retorno: vulnerabilidad de las migrantes bolivianas en Italia

    OpenAIRE

    Yépez del Castillo, Isabel; Marzadro, Mirko

    2014-01-01

    En este artículo se abordan las interrelaciones entre crisis, migración y mercado de trabajo y su incidencia en la agencia migratoria femenina, tanto en relación con la decisión inicial de migrar hacia Italia, como con la posibilidad posterior de retornar a Bolivia. A partir de la información recogida en una encuesta de gran envergadura realizada en Cochabamba y del seguimiento de diversas trayectorias migratorias femeninas, damos cuenta de la vulnerabilidad extrema a la que están sometidas l...

  3. La comunicación directiva interna en las agencias de publicidad españolas

    OpenAIRE

    Etayo Pérez, Cristina

    2008-01-01

    La comunicación interna en las empresas se ha configurado como uno de los activos estratégicos clave para la gestión. En este contexto adquiere especial relevancia la comunicación que los directivos mantienen con sus empleados. En este trabajo se analizan las acciones de comunicación de directivos de agencias de publicidad con el objetivo de obtener conclusiones sobre dos tipos de cuestiones. En primer lugar se analiza cómo los directivos de estas empresas gestionan y coordinan la comunicació...

  4. La Planificación Estratégica en la Agencia

    OpenAIRE

    Álvarez Ruiz, Xosé Antón

    2005-01-01

    Este artículo explica cómo las técnicas de la Planificación Estratégica (Strategic Planning) han entrado en las agencias de publicidad de la mano del Planner y se han desarrollado con rapidez en los últimos años. También trata de la relación entre el planner y el equipo creativo. [ABSTRAC] This article explains how the techniques of the Strategic Planning and the Planner have entered into the advertising agencies very quickly during the last past years. Also it explain the relationship ...

  5. Startup control of the TOPAZ-II space nuclear reactor

    OpenAIRE

    Astrin, Cal D.

    1996-01-01

    Approved for public release; distribution isunlimited. The Russian designed and manufactured TOPAZ-II Thermionic Nuclear Space Reactor has been supplied to the Ballistic Missile Defense Organization for study as part of the TOPAZ International Program. A Preliminary Nuclear Safety Assessment investigated the readiness to use the TOPAZ-II in support of a Nuclear Electric Propulsion Space Test Mission (NEPSTP). Among the anticipated system modifications required for launching the TOPAZ-II sy...

  6. Electromagnetic Signature Technique as a Promising Tool to Verify Nuclear Weapons Storage and Dismantlement under a Nuclear Arms Control Regime

    Energy Technology Data Exchange (ETDEWEB)

    Bunch, Kyle J.; Williams, Laura S.; Jones, Anthony M.; Ramuhalli, Pradeep

    2012-08-01

    The 2010 ratification of the New START Treaty has been widely regarded as a noteworthy national security achievement for both the Obama administration and the Medvedev-Putin regime, but deeper cuts are envisioned under future arms control regimes. Future verification needs will include monitoring the storage of warhead components and fissile materials and verifying dismantlement of warheads, pits, secondaries, and other materials. From both the diplomatic and technical perspectives, verification under future arms control regimes will pose new challenges. Since acceptable verification technology must protect sensitive design information and attributes, non-nuclear non-sensitive signatures may provide a significant verification tool without the use of additional information barriers. The use of electromagnetic signatures to monitor nuclear material storage containers is a promising technology with the potential to fulfill these challenging requirements. Research performed at Pacific Northwest National Laboratory (PNNL) has demonstrated that low frequency electromagnetic signatures of sealed metallic containers can be used to confirm the presence of specific components on a “yes/no” basis without revealing classified information. Arms control inspectors might use this technique to verify the presence or absence of monitored items, including both nuclear and non-nuclear materials. Although additional research is needed to study signature aspects such as uniqueness and investigate container-specific scenarios, the technique potentially offers a rapid and cost-effective tool to verify reduction and dismantlement of U.S. and Russian nuclear weapons.

  7. Hogares conyugales y redes sociales: la agencia de las senegalesas migrantes

    Directory of Open Access Journals (Sweden)

    Beatriz Ródenas Cerezo

    2017-06-01

    Full Text Available Comprender los diferentes tipos de agencia que ejercen las migrantes senegalesas implica tomar en consideración el contexto social, económico y familiar que las envuelve. A partir del caso de los hogares transnacionales ubicados entre Senegal y Valencia, el presente estudio clasifica los diferentes patrones organizativos hallados en los hogares conyugales senegaleses, en virtud del grado de colaboración económica que se dé en el matrimonio. A continuación se relacionan estos patrones con las diferentes presencias que las mujeres senegalesas mantienen en redes externas a la familia conyugal, en un intento de comprender por qué diferentes mujeres ejercen diferentes líneas de acción fuera del matrimonio. De esta manera, se rescata el trabajo pionero de Bott (1957[1990] sobre la relación entre los roles conyugales y las redes sociales, a la vez que se profundiza en nuestra comprensión de la agencia de las mujeres migrantes.

  8. Plant retinoblastoma homologues control nuclear proliferation in the female gametophyte.

    Science.gov (United States)

    Ebel, Chantal; Mariconti, Luisa; Gruissem, Wilhelm

    2004-06-17

    Haploid spores of plants divide mitotically to form multicellular gametophytes. The female spore (megaspore) of most flowering plants develops by means of a well-defined programme into the mature megagametophyte consisting of the egg apparatus and a central cell. We investigated the role of the Arabidopsis retinoblastoma protein homologue and its function as a negative regulator of cell proliferation during megagametophyte development. Here we show that three mutant alleles of the gene for the Arabidopsis retinoblastoma-related protein, RBR1 (ref. 4), are gametophytic lethal. In heterozygous plants 50% of the ovules are aborted when the mutant allele is maternally inherited. The mature unfertilized mutant megagametophyte fails to arrest mitosis and undergoes excessive nuclear proliferation in the embryo sac. Supernumerary nuclei are present at the micropylar end of the megagametophyte, which develops into the egg apparatus and central cell. The central cell nucleus, which gives rise to the endosperm after fertilization, initiates autonomous endosperm development reminiscent of fertilization-independent seed (fis) mutants. Thus, RBR1 has a novel and previously unrecognized function in cell cycle control during gametogenesis and in the repression of autonomous endosperm development.

  9. Anatomical relationships of the pia mater to cerebral blood vessels in man.

    Science.gov (United States)

    Hutchings, M; Weller, R O

    1986-09-01

    Using scanning and transmission electron microscopy and light microscopy, the authors studied the human pia mater and its relationship to the entry of blood vessels into the normal cerebral cortex. The purpose of this investigation was to examine the long-established concept that the subarachnoid space communicates directly with the perivascular spaces of the cerebral cortex. Brains obtained post mortem from subjects with recent subarachnoid hemorrhage (SAH) and purulent leptomeningitis were studied by light microscopy to determine the permeability of the pia mater to red blood cells and inflammatory cells. Scanning electron microscopy showed that the normal pia mater is a flat sheet of cells that is reflected from the surface of the brain to form the outer coating of the meningeal vessels in the subarachnoid space. Transmission electron microscopy confirmed that the cells of the pia mater are joined by junctional complexes and form a continuous sheet that separates the subarachnoid space on one side from the subpial and perivascular spaces on the other. Thus, neither the pia mater nor the subarachnoid space extends into the brain beside blood vessels as they enter the cerebral cortex. The perivascular spaces were, in fact, found to be confluent with the subpial space and not with the subarachnoid space. In cases of recent SAH, red blood cells did not enter the perivascular spaces from the subarachnoid space; neither did India ink injected post mortem into the subarachnoid space pass into the perivascular spaces. The results of these crude tracer studies suggest that the pia mater is an effective barrier to the passage of particulate matter. Histological examination of brains of patients who had died with purulent leptomeningitis showed that inflammatory cells were present in the cortical perivascular spaces and in the contiguous subpial spaces. The presence of a large number of inflammatory cells in the subarachnoid space suggests that inflammatory cells readily

  10. Implementing nuclear non-proliferation in Finland. Regulatory control, international cooperation and the Comprehensive Nuclear-Test-Ban Treaty. Annual report 2011

    Energy Technology Data Exchange (ETDEWEB)

    Okko, O. (ed.)

    2012-07-01

    The regulatory control of nuclear materials (i.e. nuclear safeguards) is a prerequisite for the peaceful use of nuclear energy in Finland. Safeguards are required for Finland to comply with international agreements on nuclear non-proliferation - mainly the Non-Proliferation Treaty (NPT). This regulatory control is exercised by the Nuclear Materials Section of the Finnish Radiation and Nuclear Safety Authority (STUK). The results of STUK's nuclear safeguards inspection activities in 2011 continued to demonstrate that the Finnish licence holders take good care of their nuclear materials. There were no indications of undeclared nuclear materials or activities and the inspected materials and activities were in accordance with the licence holders' declarations.

  11. A comparative study on export control systems of nuclear technology in ROK and USA

    Energy Technology Data Exchange (ETDEWEB)

    Tae, Jae Woong; Shin, Dong Hoon [Korea Institute of Nuclear Nonproliferation and Control, Daejeon (Korea, Republic of)

    2013-10-15

    Perfect removal of transferred technology is impossible because it is impossible to find all copies of technologies such as files and documents. International community concerns about Terrorists' acquirement of nuclear technologies related to nuclear reactors, enrichment and reprocessing Facilities and heavy water production facilities, which can be used for production of nuclear weapons. Non-state actors as well as concerning countries have tried to possess nuclear technology for developing nuclear weapons. Non-state actors' activities threaten global nuclear security. Korea exported four nuclear power plants to UAE and a research reactor to Jordan. Non-state actors may try to procure nuclear equipment and technology from Korean nuclear industries. Therefore, the export control system should be enhanced for national nuclear security and safety. In this study, the export control system of Korea and the United States were compared concerning to nuclear technology. In summary, controlled activities related to nuclear technology are treated more variously and more diverse activities are controlled in the United States than In Korea. Catch-all control will lose its effectiveness without this. Related to the control of ITT (Intangible Technology Transfer), Korea and the United States are trying to amend the export control regulation. Both of them are trying to control intangible technology transfers effectively. Revised Foreign Trade Act in Korea is expected to introduce a more rigorous system of nuclear technology controls. It focuses on nationality rather than residence. The revised law may face into other problems such as dual nationals like as the United States. However, this satisfies legislative requirements for control of a deemed export. The revised law will enter into force in 2014. Accurate meanings of technology and export will be defined soon in the enforcement decree and the public notice before 2014. However, it is hard to revise the definition

  12. Radioactive Iodine and Krypton Control for Nuclear Fuel Reprocessing Facilities

    Energy Technology Data Exchange (ETDEWEB)

    Soelberg, Nicolas R.; Garn, Troy; Greenhalgh, Mitchell; Law, Jack; Jubin, Robert T.; Strachan, Denis M.; Thallapally, Praveen K.

    2013-07-22

    Nuclear fission results in the production of fission products and activation products, some of which tend to be volatile during used fuel reprocessing. These can evolve in volatile species in the reprocessing facility off-gas streams, depending on the separations and reprocessing technologies that are used. Radionuclides that have been identified as “volatile radionuclides” are noble gases (most notably isotopes of Kr and Xe); 3H; 14C; and 129I. Radionuclides that tend to form volatile species that evolve into reprocessing facility off-gas systems are more challenging to efficiently control compared to radionuclides that tend to stay in solid or liquid phases. Future used fuel reprocessing facilities in the United States can require efficient capture of some volatile radionuclides in their off-gas streams to meet regulatory emission requirements. In aqueous reprocessing, these radionuclides are most commonly expected to evolve into off-gas streams in tritiated water [3H2O (T2O) and 3HHO (THO)], radioactive CO2, noble gases, and gaseous HI, I2, or volatile organic iodides. The fate and speciation of these radionuclides from a non-aqueous fuel reprocessing facility is less well known at this time, but active investigations are in progress. An Off-Gas Sigma Team was formed in late FY 2009 to integrate and coordinate the Fuel Cycle Research and Development (FCR&D) activities directed towards the capture and sequestration of the these volatile radionuclides (Jubin 2012a). The Sigma Team concept was envisioned to bring together multidisciplinary teams from across the DOE complex that would work collaboratively to solve the technical challenges and to develop the scientific basis for the capture and immobilization technologies such that the sum of the efforts was greater than the individual parts. The Laboratories currently participating in this effort are Argonne National Laboratory (ANL), Idaho National Laboratory (INL), Oak Ridge National Laboratory (ORNL), Pacific

  13. Addendum: Compliant electrostatic chuck based on hairy microstructure (2013 Smart Mater. Struct. 22 015019) and Electrostatic chuck consisting of polymeric electrostatic inductive fibers for handling of objects with rough surfaces (2013 Smart Mater. Struct. 22 095010)

    Science.gov (United States)

    Saito, Shigeki; Kikutani, Takeshi; Takahashi, Kunio; Takarada, Wataru; Soda, Fumiaki; Sawai, Kenji; Dhelika, Radon

    2014-07-01

    The recent papers Saito et al 2013 Smart Mater. Struct. 22 015019 and Dhelika et al 2013 Smart Mater. Struct. 22 095010 described studies of an electrostatic chuck that mimics the structure of gecko-like toes. Earlier work published by the authors and other researchers is cited to further illustrate the origin and motivation of the research.

  14. The ANEEL and the PL 3.337/2004; analysis of the management, organization and social control of the regulator agencies under the legal optics; A ANEEL e o PL 3.337/2004: uma analise da gestao, organizacao e controle social das agencias reguladoras sob o prisma juridico

    Energy Technology Data Exchange (ETDEWEB)

    Costa, Hirdan Katarina de Medeiros; Bermann, Celio [Universidade de Sao Paulo (USP), SP (Brazil). Inst. de Eletrotecnica e Energia. Programa Interunidades de Pos-Graduacao em Energia]. E-mails: hirdanmedeiros@iee.usp.br; cbermann@iee.usp.br

    2006-07-01

    Since 1990 movement of opening economic sectors and public services long ago explored only the State in Brazil, what it parallel caused the institution of agencies with the target to oversee and to regulate definitive sector affection to the utility public. Ahead of this context, the agency process was attended to it, with looks it to monitor, to regulate and to oversee the activities of steady the incoming actors and already in these markets by means of specific and various laws. Thus, justifying the importance of the existence of a General Law of the Regulating Agencies, the Legislative Bill meets in the National Congress no. 3.337/04. Therefore, the present work, by means of bibliographical research and analysis the Bill in question, it intended to approach the points most controversial raised by studious of the Brazilian right in relation to the impact of the these changes proposals in the structure of the National Agency of Electric Energy. In this direction, the main focus was the contract of management, the interaction between the agencies and the institutions of free market defense, the agencies of control and the public hearings and consultations. (author)

  15. Progress of nuclear safety for symbiosis and sustainability advanced digital instrumentation, control and information systems for nuclear power plants

    CERN Document Server

    Yoshikawa, Hidekazu

    2014-01-01

    This book introduces advanced methods of computational and information systems allowing readers to better understand the state-of-the-art design and implementation technology needed to maintain and enhance the safe operation of nuclear power plants. The subjects dealt with in the book are (i) Full digital instrumentation and control systems and human?machine interface technologies (ii) Risk? monitoring methods for large and? complex? plants (iii) Condition monitors for plant components (iv) Virtual and augmented reality for nuclear power plants and (v) Software reliability verification and val

  16. Nonlinear Fuzzy Model Predictive Control for a PWR Nuclear Power Plant

    Directory of Open Access Journals (Sweden)

    Xiangjie Liu

    2014-01-01

    Full Text Available Reliable power and temperature control in pressurized water reactor (PWR nuclear power plant is necessary to guarantee high efficiency and plant safety. Since the nuclear plants are quite nonlinear, the paper presents nonlinear fuzzy model predictive control (MPC, by incorporating the realistic constraints, to realize the plant optimization. T-S fuzzy modeling on nuclear power plant is utilized to approximate the nonlinear plant, based on which the nonlinear MPC controller is devised via parallel distributed compensation (PDC scheme in order to solve the nonlinear constraint optimization problem. Improved performance compared to the traditional PID controller for a TMI-type PWR is obtained in the simulation.

  17. Page 1 Bull. Mater. Sci., Vol. 17, No. 6, November 1994, pp. 999-004 ...

    Indian Academy of Sciences (India)

    Bull. Mater. Sci., Vol. 17, No. 6, November 1994, pp. 999-004, C Printed in India. Role of dopant cations in the gelation behaviour of silica sols. A PATRA and D GANGULI. Sol-Gel Laboratory, Central Glass & Ceramic Research Institute, Calcutta 700 032, India. Abstract. Gelation times of tetraethyl orthosilicate-derived sols ...

  18. 76 FR 36993 - Medical Devices; Neurological Devices; Clarification of Classification for Human Dura Mater...

    Science.gov (United States)

    2011-06-24

    ... Drug Administration (FDA) is amending the device regulations to clarify the applicability of the device... of the final rule, human dura mater was regulated as a medical device under Sec. 882.5975. As stated... CFR Part 882 Medical devices, Neurological devices. Therefore, under the Federal Food, Drug, and...

  19. Interaction of ionizing radiation with mater; Oddzialywanie promieniowania jonizujacego z materia

    Energy Technology Data Exchange (ETDEWEB)

    Pogocki, D. [Institute of Nuclear Chemistry and Technology, Warsaw (Poland)

    1997-10-01

    The early radiation effects (e.g. excitation, ionization) have been described and compared for different kind of radiation interacting with mater. The mechanism of energy deposition in connection with radiation dose and their spatial distribution has been shown.The commonly used definitions and units in radiation dosimetry have been also reviewed. 4 refs, 4 figs.

  20. Migration of Older to New Digital Control Systems in Nuclear Power Plant Main Control Rooms

    Energy Technology Data Exchange (ETDEWEB)

    Kovesdi, Casey Robert [Idaho National Lab. (INL), Idaho Falls, ID (United States); Joe, Jeffrey Clark [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2016-04-01

    The United States (U.S.) Department of Energy (DOE) Office of Nuclear Energy (NE) has the primary mission to advance nuclear power by resolving socio-technical issues through research and development (R&D). One DOE-NE activity supporting this mission is the Light Water Reactor Sustainability (LWRS) program. LWRS has the overall objective to sustain the operation of existing commercial nuclear power plants (NPPs) through conducting R&D across multiple “pathways,” or R&D focus areas. The Advanced Instrumentation, Information, and Control (II&C) Systems Technologies pathway conducts targeted R&D to address aging and reliability concerns with the legacy instrumentation and control (I&C) and related information systems in operating U.S. NPPs. This work involves (1) ensuring that legacy analog II&C systems are not life-limiting issues for the LWR fleet, and (2) implementing digital II&C technology in a manner that enables broad innovation and business improvement in the NPP operating model. Under the LWRS Advanced II&C pathway, Human Factors experts at Idaho National Laboratory (INL) have been conducting R&D in support of NPP main control room (MCR) modernization activities. Work in prior years has focused on migrating analog I&C systems to new digital I&C systems (). In fiscal year 2016 (FY16), one new focus area for this research is migrating older digital I&C systems to new and advanced digital I&C systems. This report summarizes a plan for conducting a digital-to-digital migration of a legacy digital I&C system to a new digital I&C system in support of control room modernization activities.

  1. Routine quality control of clinical nuclear medicine instrumentation: a brief review.

    Science.gov (United States)

    Zanzonico, Pat

    2008-07-01

    This article reviews routine quality-control (QC) procedures for current nuclear medicine instrumentation, including the survey meter, dose calibrator, well counter, intraoperative probe, organ ("thyroid") uptake probe, gamma-camera, SPECT and SPECT/CT scanner, and PET and PET/CT scanner. It should be particularly useful for residents, fellows, and other trainees in nuclear medicine, nuclear cardiology, and radiology. The procedures described and their respective frequencies are presented only as general guidelines.

  2. Routine Quality Control of Clinical Nuclear Medicine Instrumentation: A Brief Review*

    OpenAIRE

    Zanzonico, Pat

    2008-01-01

    This article reviews routine quality-control (QC) procedures for current nuclear medicine instrumentation, including the survey meter, dose calibrator, well counter, intraoperative probe, organ (“thyroid”) uptake probe, γ-camera, SPECT and SPECT/CT scanner, and PET and PET/CT scanner. It should be particularly useful for residents, fellows, and other trainees in nuclear medicine, nuclear cardiology, and radiology. The procedures described and their respective frequencies are presented only as...

  3. Establishment of a national program for quality control of nuclear medicine instrumentation.

    Science.gov (United States)

    Coca Perez, Marco A; Torres Aroche, Leonel A; Bejerano, Gladys López; Mayor, Roberto Fraxedas; Corona, Consuelo Varela; López, Adlin

    2008-12-01

    Monitoring the quality of instrumentation used in nuclear medicine is mandatory to guarantee the clinical efficacy of medical practice. A national program for the quality control of nuclear medicine instruments was established in Cuba and was certified and approved by the regulatory authorities. The program, which establishes official regulations and audit services, sets up educational activities, distributes technical documentation, and maintains a national phantom bank, constitutes a valuable and useful tool to guarantee the quality of nuclear medicine instrumentation.

  4. El espionaje y agencias de seguridad: los Estados Unidos y la Federación Rusa

    Directory of Open Access Journals (Sweden)

    Daniela Alejandra Alba Useche

    2014-01-01

    Full Text Available La evolución del espionaje y la tecnología desde la Guerra Fría entre los Estados Unidos y la Federación Rusa se ha desarrollado a través de las Agencias de Seguridad, pero desde los ataques del 11-S, hubo un giro en los métodos de atacar el terrorismo; este tema se convirtió en la prioridad para Estados Unidos y para el resto del mundo. Por esta razón, se están desarrollando vertiginosamente programas de vigilancia, recopilación y análisis de información, sirviéndose del ciberespacio y del ciberespionaje, donde ahora todos somos observados y la privacidad ha sido reemplazada por la vigilancia ‘en aras’ de la seguridad.

  5. El contrato de agencia comercial. Análisis dentro del contexto del derecho romano

    Directory of Open Access Journals (Sweden)

    María Elisa Camacho López

    2009-06-01

    Full Text Available Sumario: Premisa. Principios derivados del sistema jurídico romano-germánico aplicables al contrato de agencia comercial. i. Algunas figuras de la actividad mercantil en el derecho romano. ii. Cláusulas de no competencia. A. Posibles fuentes de la obligación de no competencia en el derecho romano. 1. Obsequium. 2. Operae iuratae. 3. Operae stipulatae. 4. Stipulatio. 5. Contratos innominados. 6. Lex mancipii. B. Licitud o ilicitud de la obligación de no competencia en el derecho romano. C. Condena por el incumplimiento de la obligación de no competir. iii. Consecuencias de la terminación del contrato. A. Revocación del mandato por parte del mandante. B. Renuncia del mandato por parte del mandatario. iv. Conclusiones

  6. Notas sobre modernidad, decolonialidad y agencia cultural en Latinoamérica

    Directory of Open Access Journals (Sweden)

    Salvador Leetoy

    2016-08-01

    Full Text Available Este artículo hace una reflexión sobre apropiaciones de la modernidad que influyen en la condición latinoamericana en el marco de sus procesos decoloniales. Se discute cómo la diversidad de estrategias de agencia cultural de la zona construye una modernidad desde abajo constituida de manera transgresiva. Se establece que, pensar en Latinoamérica como un mero pastiche ideológico que combina discursos de la premodernidad, la modernidad y la posmodernidad, obedece más a una óptica eurocéntrica ajena a sus condiciones históricas, sociales y políticas, que a una reflexión contextual de las circunstancias que han ido determinando nuestra particular condición subalterna.

  7. Agencias de empleo y desarrollo local: ¿una actividad del Tercer Sector?

    Directory of Open Access Journals (Sweden)

    Ricardo Calvo Palomares

    2010-01-01

    Full Text Available En la actualidad, el desarrollo económico y social de un territorio necesita de los esfuerzos mancomunados de todos y cada uno de los agentes presentes en el medio. Es por ello que el presente artículo pretende reflexionar sobre la vinculación directa existente entre dos de ellos, por un lado las Agencias de Desarrollo Local (ADL como máximo exponente del modelo de desarrollo local y por otro las organizaciones pertenecientes al Tercer Sector, como entidades clave en el sostenimiento y desarrollo social de la comunidad. Para ello partiendo de las características propias del modelo actual de desarrollo local implantado, propondremos dos decálogos de conclusiones, que analicen tanto las similitudes como las divergencias existentes entre estos dos modelos.

  8. El maestro y las lentejuelas. Pensar la intervención feminista desde las agencias culturales

    Directory of Open Access Journals (Sweden)

    María Teresa Garzón Martínez

    2017-06-01

    Full Text Available El presente artículo tiene como objetivo pensar una modalidad de intervención feminista desde las agencias culturales y, al mismo tiempo, sistematizar una experiencia que tiene como base la Investigación Acción Participativa (IAP, con el ánimo de poner a discusión supuestos teóricos, metodológicos y políticos al respecto. Tanto los hallazgos aquí presentados como la originalidad del proyecto se encuentran en posicionar el trabajo con y desde la cultura como necesario para el feminismo, y en demostrar la utilidad de la IAP como itinerario de investigación y sustento de intervención.

  9. Dura mater mitral and tricuspid bioprostheses: 30 years of follow-up Bioprótese de dura mater mitral e tricúspide: 30 anos de acompanhamento

    Directory of Open Access Journals (Sweden)

    Luiz Boro Puig

    2003-01-01

    Full Text Available PURPOSE: The dura mater bioprosthesis was developed in the Department of Cardiopneumology of the Hospital das Clínicas of the University of São Paulo Medical School in 1971. Here, we present the clinical results of the dura mater bioprosthesis over 30 years of follow-up. METHODS: We studied 70 consecutive patients who underwent mitral or tricuspid valve replacement with a dura mater bioprosthesis between January 1971 and August 1972. RESULTS: The early mortality was 10% (7 patients. The follow-up was 87% complete (9 patients were lost to follow-up. Two patients were alive and asymptomatic 30 years after valve replacement; 33 patients underwent reoperations due to valve dysfunction, and 19 died during the follow-up period. At 30 years, the actuarial survival was 49.2 ± 8.6%; freedom from rupture, 27.0 ± 10.2%; freedom from calcification, 78.8 ± 8.6%; and freedom from reoperation, 18.8 ± 7.5%. CONCLUSIONS: The dura mater bioprosthesis played an important role in the treatment of patients with mitral and tricuspid valve disease. The low rate of thromboembolism and the long period of follow-up without evidence of valve dysfunction, which occurred for several of our patients, are important characteristics of these bioprosthesis.A bioprótese de dura-mater foi desenvolvida no Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo em 1971. Este trabalho apresenta os resultados clínicos com 30 anos de seguimento. MÉTODOS: Foram estudados 70 pacientes consecutivos com bioprótese mitral ou tricúspide, operados de janeiro de 1971 a agosto de 1972. RESULTADOS: A mortalidade imediata foi 10% (7 pacientes. Dois pacientes evoluem bem com a bioprótese de dura-máter, 9 não tem seguimento atualizado, 33 apresentaram disfunção da bioprotese e foram reoperados e 19 faleceram durante a evolução tardia. A curva atuarial de sobrevida foi de 49,2 ± 8,6%, livre de rotura, 27,0 ± 10,2%, livre de calcificação, 78,8 ± 8,6% e

  10. Controlling the Proliferation of Nuclear Weapons: Study Guide for Teachers and Students

    Science.gov (United States)

    United States Institute of Peace, 2005

    2005-01-01

    The objectives of this teaching guide are: (1) to increase student understanding of the prevalence and spread of nuclear weapons; (2) to familiarize students with historic and contemporary measures to control nuclear proliferation and stimulate their thinking of potential strategies for doing so in the future; (3) to develop students' analytical…

  11. Temporal control of nuclear envelope assembly by phosphorylation of lamin B receptor.

    Science.gov (United States)

    Tseng, Li-Chuan; Chen, Rey-Huei

    2011-09-01

    The nuclear envelope of metazoans disassembles during mitosis and reforms in late anaphase after sister chromatids have well separated. The coordination of these mitotic events is important for genome stability, yet the temporal control of nuclear envelope reassembly is unknown. Although the steps of nuclear formation have been extensively studied in vitro using the reconstitution system from egg extracts, the temporal control can only be studied in vivo. Here, we use time-lapse microscopy to investigate this process in living HeLa cells. We demonstrate that Cdk1 activity prevents premature nuclear envelope assembly and that phosphorylation of the inner nuclear membrane protein lamin B receptor (LBR) by Cdk1 contributes to the temporal control. We further identify a region in the nucleoplasmic domain of LBR that inhibits premature chromatin binding of the protein. We propose that this inhibitory effect is partly mediated by Cdk1 phosphorylation. Furthermore, we show that the reduced chromatin-binding ability of LBR together with Aurora B activity contributes to nuclear envelope breakdown. Our studies reveal for the first time a mechanism that controls the timing of nuclear envelope reassembly through modification of an integral nuclear membrane protein.

  12. Lessons from UNSCOM/IAEA applicable to nuclear arms control

    Energy Technology Data Exchange (ETDEWEB)

    Dorn, D.W.

    1995-12-05

    In early 1991, the Security Council of the United Nations tasked the Director General of the International Atomic Energy Agency, with the assistance and cooperation of the United Nations Special Commission, to oversee the destruction, removal or rendering harmless of nuclear weapons material and capabilities in Iraq. The conduct of the nuclear inspections, and the subsequent activities (identification, destruction, removal rendering harmless), have provided a wealth of experience and insight into the inspection and monitoring process as well as into the political realities of such an operation. The early inspections were conducted in an atmosphere of discovery and inexperience on both the part of the Iraqis and the IAEA and UNSCOM. As time went on, the Iraqis became more adept at hiding and obscuring relevant documents and equipment, and the inspection teams became more knowledgeable about inspection and investigative techniques, and the pre-existing Iraqi programs. A continuous monitoring presence in Iraq has now been established and an import/export monitoring regime is being developed. While steps taken to date have proven effective in inhibiting resumption of nuclear weaponization activities, it remains to be seen how effective these measures will be in the future. The external and internal conditions which led the Iraqi leadership to undertake a nuclear weaponization program have not changed, and the prognosis for the long term is uncertain. The entire process in Iraq has shown how fragile are the tools available to the international community, and how a determined proliferator can evade inspection and monitoring measures. Such measures cannot prevent nuclear proliferation, they can only hope to deter it, or, failing in that, detect it.

  13. Nuclear receptors linking circadian rhythms and cardiometabolic control.

    Science.gov (United States)

    Duez, Hélène; Staels, Bart

    2010-08-01

    Many behavioral and physiological processes, including locomotor activity, blood pressure, body temperature, sleep (fasting)/wake (feeding) cycles, and metabolic regulation display diurnal rhythms. The biological clock ensures proper metabolic alignment of energy substrate availability and processing. Studies in animals and humans highlight a strong link between circadian disorders and altered metabolic responses and cardiovascular events. Shift work, for instance, increases the risk to develop metabolic abnormalities resembling the metabolic syndrome. Nuclear receptors have long been known as metabolic regulators. Several of them (ie, Rev-erbalpha, RORalpha, and peroxisome proliferation-activated receptors) are subjected to circadian variations and are integral components of molecular clock machinery. In turn, these nuclear receptors regulate downstream target genes in a circadian manner, acting to properly gate metabolic events to the appropriate circadian time window.

  14. Control of radioactive waste in dismantling of a nuclear facility; Control de residuos radiactivos en desmantelamiento de una instalacion nuclear

    Energy Technology Data Exchange (ETDEWEB)

    Campayo, E.

    2014-07-01

    In the dismantling of a nuclear facility are generated radioactive waste that must be suitably processed. The overall process, in a simplified manner, contemplates the characterization in origin, their segregation on the basis of physical, mechanical, and radiological characteristics and their packaging. (Author)

  15. Claudia Quinta (Pro Caelio 34 and an altar to Magna Mater

    Directory of Open Access Journals (Sweden)

    Eleanor Winsor Leach

    2010-11-01

    Full Text Available Among the items of sculpture from the Capitoline collection now housed in the Museum of the Power Station Montemartini is a marble relief altar of the Claudian Period (E. Simon's dating dedicated to the mater deorum and the navis salvia and depicting the arrival of the goddess Cybele at Rome by ship. The dedicator is one Claudia Syntyche and the sculpture alludes to the legends attached to a much honored woman of the Claudian family whom Cicero, in his oration pro Caelio brought on stage in a cameo appearance to bolster his case against the controversial contemporary woman Clodia Metelli as one of the accusers of his client M. Caelius Rufus. This paper will consider questions raised by the iconography of the altar with reference to the development of Claudia's legend in Roman mythology and subsequently ask who was this Claudia the dedicator and why did she choose Magna Mater for her vow?

  16. Adaptive Neural Network Algorithm for Power Control in Nuclear Power Plants

    Science.gov (United States)

    Masri Husam Fayiz, Al

    2017-01-01

    The aim of this paper is to design, test and evaluate a prototype of an adaptive neural network algorithm for the power controlling system of a nuclear power plant. The task of power control in nuclear reactors is one of the fundamental tasks in this field. Therefore, researches are constantly conducted to ameliorate the power reactor control process. Currently, in the Department of Automation in the National Research Nuclear University (NRNU) MEPhI, numerous studies are utilizing various methodologies of artificial intelligence (expert systems, neural networks, fuzzy systems and genetic algorithms) to enhance the performance, safety, efficiency and reliability of nuclear power plants. In particular, a study of an adaptive artificial intelligent power regulator in the control systems of nuclear power reactors is being undertaken to enhance performance and to minimize the output error of the Automatic Power Controller (APC) on the grounds of a multifunctional computer analyzer (simulator) of the Water-Water Energetic Reactor known as Vodo-Vodyanoi Energetichesky Reaktor (VVER) in Russian. In this paper, a block diagram of an adaptive reactor power controller was built on the basis of an intelligent control algorithm. When implementing intelligent neural network principles, it is possible to improve the quality and dynamic of any control system in accordance with the principles of adaptive control. It is common knowledge that an adaptive control system permits adjusting the controller’s parameters according to the transitions in the characteristics of the control object or external disturbances. In this project, it is demonstrated that the propitious options for an automatic power controller in nuclear power plants is a control system constructed on intelligent neural network algorithms.

  17. Study and development of advanced control techniques for nuclear reactors and robots

    Energy Technology Data Exchange (ETDEWEB)

    March-Leuba, C.

    1989-08-01

    This report studies and develops some aspects of the optimal control theory with the objective of evaluating benefits that the nuclear industry could obtain by applying advanced control techniques. First, the basic relationship between optimal control theory and closed-loop control design has been identified. As a result of this work, new algorithms have been developed for feedback implementations. The applicability of these new algorithms to problems such as state estimation, filtering, model update, and model decoupling has been studied. In addition, new alternatives to control design that are not based on optimal control theory have been developed. A broad range of application examples has been presented for several physical systems, including pressurized water nuclear reactors, boiling water nuclear reactors, steam generators, and robotics. 22 refs., 26 figs.

  18. Effects of Radiation on Spinal Dura Mater and Surrounding Tissue in Mice.

    Directory of Open Access Journals (Sweden)

    Noriaki Yokogawa

    Full Text Available Spinal surgery in a previously irradiated field carries increased risk of perioperative complications, such as delayed wound healing or wound infection. In addition, adhesion around the dura mater is often observed clinically. Therefore, similar to radiation-induced fibrosis--a major late-stage radiation injury in other tissue--epidural fibrosis is anticipated to occur after spinal radiation. In this study, we performed histopathologic assessment of postirradiation changes in the spinal dura mater and peridural tissue in mice.The thoracolumbar transition of ddY mice was irradiated with a single dose of 10 or 20 Gy. After resection of the irradiated spine, occurrence of epidural fibrosis and expression of transforming growth factor beta 1 in the spinal dura mater were evaluated. In addition, microstructures in the spinal dura mater and peridural tissue were assessed using an electron microscope.In the 20-Gy irradiated mice, epidural fibrosis first occurred around 12 weeks postirradiation, and was observed in all cases from 16 weeks postirradiation. In contrast, epidural fibrosis was not observed in the nonirradiated mice. Compared with the nonirradiated mice, the 10- and 20-Gy irradiated mice had significantly more overexpression of transforming growth factor beta 1 at 1 week postirradiation and in the late stages after irradiation. In microstructural assessment, the arachnoid barrier cell layer was thinned at 12 and 24 weeks postirradiation compared with that in the nonirradiated mice.In mice, spinal epidural fibrosis develops in the late stages after high-dose irradiation, and overexpression of transforming growth factor beta 1 occurs in a manner similar to that seen in radiation-induced fibrosis in other tissue. Additionally, thinning of the arachnoid barrier cell layer was observed in the late stages after irradiation. Thus, consideration should be given to the possibility that these phenomena can occur as radiation-induced injuries of the

  19. Effects of Radiation on Spinal Dura Mater and Surrounding Tissue in Mice.

    Science.gov (United States)

    Yokogawa, Noriaki; Murakami, Hideki; Demura, Satoru; Kato, Satoshi; Yoshioka, Katsuhito; Yamamoto, Miyuki; Iseki, Shoichi; Tsuchiya, Hiroyuki

    2015-01-01

    Spinal surgery in a previously irradiated field carries increased risk of perioperative complications, such as delayed wound healing or wound infection. In addition, adhesion around the dura mater is often observed clinically. Therefore, similar to radiation-induced fibrosis--a major late-stage radiation injury in other tissue--epidural fibrosis is anticipated to occur after spinal radiation. In this study, we performed histopathologic assessment of postirradiation changes in the spinal dura mater and peridural tissue in mice. The thoracolumbar transition of ddY mice was irradiated with a single dose of 10 or 20 Gy. After resection of the irradiated spine, occurrence of epidural fibrosis and expression of transforming growth factor beta 1 in the spinal dura mater were evaluated. In addition, microstructures in the spinal dura mater and peridural tissue were assessed using an electron microscope. In the 20-Gy irradiated mice, epidural fibrosis first occurred around 12 weeks postirradiation, and was observed in all cases from 16 weeks postirradiation. In contrast, epidural fibrosis was not observed in the nonirradiated mice. Compared with the nonirradiated mice, the 10- and 20-Gy irradiated mice had significantly more overexpression of transforming growth factor beta 1 at 1 week postirradiation and in the late stages after irradiation. In microstructural assessment, the arachnoid barrier cell layer was thinned at 12 and 24 weeks postirradiation compared with that in the nonirradiated mice. In mice, spinal epidural fibrosis develops in the late stages after high-dose irradiation, and overexpression of transforming growth factor beta 1 occurs in a manner similar to that seen in radiation-induced fibrosis in other tissue. Additionally, thinning of the arachnoid barrier cell layer was observed in the late stages after irradiation. Thus, consideration should be given to the possibility that these phenomena can occur as radiation-induced injuries of the spine.

  20. A quality control method for nuclear instrumentation and control systems based on software safety prediction

    Science.gov (United States)

    Son, Han Seong; Seong, Poong Hyun

    2000-04-01

    In the case of safety-related applications like nuclear instrumentation and control (NI&C), safety-oriented quality control is required. The objective of this paper is to present a software safety classification method as a safety-oriented quality control tool. Based on this method, we predict the risk (and thus safety) of software items that are at the core of NI&C systems. Then we classify the software items according to the degree of the risk. The method can be used earlier than at the detailed design phase. Furthermore, the method can also be used in all the development phases without major changes. The proposed method seeks to utilize the measures that can be obtained from the safety analysis and requirements analysis. Using the measures proved to be desirable in a few aspects. The authors have introduced fuzzy approximate reasoning to the classification method because experts' knowledge covers the vague frontiers between good quality and bad quality with linguistic uncertainty and fuzziness. Fuzzy Colored Petri Net (FCPN) is introduced in order to offer a formal framework for the classification method and facilitate the knowledge representation, modification, or verification. Through the proposed quality control method, high-quality NI&C systems can be developed effectively and used safely.

  1. A quantitative comparison of dura mater tissue structures measured with atomic force microscopy.

    Science.gov (United States)

    Sikora, Andrzej; Kedzia, Alicja

    2012-01-01

    The growth of a human embryo is a very sophisticated process. Understanding the way it proceeds is a key factor in pathology preventing and treating diseases. Therefore one needs to use advanced to tools and methods to investigate various aspects of the anatomy and physiology of humans during the first months of growth. This work is focused on the structure of dura mater tissue, one of the membranes protecting the brain, which can be responsible for a number of health issues if it develops abnormally. The aim of the work was to observe dura mater tissue structure with atomic force microscopy and to provide a quantitative method of discrimination of both the periosteal and meningeal layers in a 6-month-old human embryo. The measurements were performed with atomic force microscopy, in air, using tapping mode. The sample was stored in formaldehyde and dried prior to the measurements. The results obtained permitted observation of the structure of the tissue, in particular the presence of collagen fibers. By applying various image analysis tools, quantitative descriptions of both layers were created in order to distinguish them. The experiment proved that atomic force microscopy can be a useful tool in the investigation of the development process of the dura mater tissue in terms of the appearance of differences related to various functions of the periosteal and meningeal layers.

  2. Development of a PID-Fuzzy controller in the water level control of a pressurizer of a nuclear reactor

    Energy Technology Data Exchange (ETDEWEB)

    Brito, Thiago S.P.; Lira, Carlos A.B.O.; Vasconcelos, Wagner E., E-mail: thiago.brito86@yahoo.com.br, E-mail: cabol@ufpe.br, E-mail: wagner@unicap.br [Universidade Federal de Pernambuco (UFPE), Recife, PE (Brazil). Centro de Tecnologia e Geociencias. Departamento de Energia Nuclear; Universidade Catolica de Pernambuco (UNICAP), Recife, PE (Brazil). Centro de Ciencias e Tecnologia

    2017-11-01

    It is well known that safety in the operation of nuclear power plants is a primary requirement because a failure of this system can result in serious problems to the environment. A nuclear reactor has several systems that help keep it in normal operation, within safety margins. Many of these systems operate in the control of variable quantities in the primary circuit of a reactor. However, nuclear reactors are nonlinear physical systems, and this introduces a complexity in the control strategies. Among several mechanisms in the thermal-hydraulic system of a reactor that actuate as a controller, the pressurizer is the component responsible for absorbing pressure variations that occur in the primary circuit. This work aims at the development of a PID controller (Proportional Integral Derivative) based on fuzzy logic to operate in a pressurizer of a nuclear Pressurized Water Reactor. A Fuzzy Controller was developed using the process of fuzzification, inference, and defuzzification of the variables of interest to a pressurizer, then this controller was coupled to a PID Controller building a PID Controller, but oriented by Fuzzy logic. Subsequently, the PID-Fuzzy Controller was experimentally validated in a Simulation Plant in which transients like those in a PWR were conducted. The PID parameters were analyzed and adjusted for better responses and results. The results of the validation were also compared to simple controllers (on / off). (author)

  3. Satellite Surveillance of Nuclear Plant, Assisting IAEA Control

    Science.gov (United States)

    Mileikowsky, Curt

    1997-01-01

    One of the great problems for world society today is what to do with the 100 000 tons of spent fuel — produced by 400 power reactors in over 30 nations — that contain 1000 tons of civilian plutonium and that will double in volume over the next 10 to 15 years. That future amount of civilian plutonium represents material for 400 000 nuclear bombs: simple ones, relatively easily made, ideal for terrorists, of the strength of 10-70% of the Hiroshima bomb. Because of this risk, spent fuel has to be safeguarded for 10 000 years. The most straightforward way to eliminate the need for safeguarding spent fuel would be to burn it. That could best be done with an accelerator-driven subcritical reactor, i.e. one that cannot function without the assistance of a 1-2.5 GeV proton accelerator supplying the lacking neutrons and which therefore makes for an extremely safe plant that cannot run amok (as Chernobyl did for example). 100 of such plant could burn all the plutonium produced by the 400 present-type reactors in the world and simultaneously produce profitable electric power. But such a scheme requires proof that the accelerators could not themselves be used for producing nuclear bomb material. That utterly important task for world society could be significantly supported by the new commercial high resolution observation satellites.

  4. OVERVIEW OF A RECONFIGURABLE SIMULATOR FOR MAIN CONTROL ROOM UPGRADES IN NUCLEAR POWER PLANTS

    Energy Technology Data Exchange (ETDEWEB)

    Ronald L. Boring

    2012-10-01

    This paper provides background on a reconfigurable control room simulator for nuclear power plants. The main control rooms in current nuclear power plants feature analog technology that is growing obsolete. The need to upgrade control rooms serves the practical need of maintainability as well as the opportunity to implement newer digital technologies with added functionality. There currently exists no dedicated research simulator for use in human factors design and evaluation activities for nuclear power plant modernization in the U.S. The new research simulator discussed in this paper provides a test bed in which operator performance on new control room concepts can be benchmarked against existing control rooms and in which new technologies can be validated for safety and usability prior to deployment.

  5. Autenticidad, marca personal y agencia sexual: el posfeminismo lésbico en youtube

    Directory of Open Access Journals (Sweden)

    Antonio Caballero Gálvez

    2017-12-01

    Full Text Available Youtube, espacio mediático postelevisivo por excelencia, modifica los códigos de representación y comunicación entre jóvenes sobre temas como la identidad y la orientación sexual. Así, la plataforma de vídeo se ha convertido en el arma definitiva del activismo LGTBQ (Polo, 2016 donde gays, lesbianas, bisexuales y queers se abren paso en la red. Esto ocurre mientras el posfeminismo se consolida en los medios mainstream como lo que parece la única vía de representación femenina: ostentado en numerosas ocasiones por iconos de la cultura popular, el posfeminismo se caracteriza por un efecto ‘rebote’ contra el feminismo histórico, reivindicando una mujer liberada, asertiva y auténtica, obviando así las injusticias del patriarcado que siguen existiendo (Tasker y Negra, 2005; Gill, 2007. Los patrones de estas representaciones posfeministas están vinculadas por una parte con la autenticidad, el éxito, la libertad de elección y el empoderamiento femenino y, por otra parte, con la agencia sexual de las mujeres y el uso que éstas hacen de su cuerpo para conseguir privilegios. Este estudio indaga en cómo las representaciones de youtubers lesbianas, por una parte, reproducen y, por otra parte, se resisten a este posfeminismo mainstream. Con este objetivo hemos seleccionado una muestra de cinco youtubers lesbianas españolas con un gran número de suscriptores (YellowMellow, Dulceida, Xuri Fenton, Gominuke, Koala Rabioso. Los resultados muestran, por un lado, la gestión del propio cuerpo principalmente situada fuera de la mirada masculina y generadora de nuevos imaginarios - en este caso, lésbicos. Esto otorga a las youtubers lesbianas una agencia sexual que no está enmarcada en el posfeminismo, sino que desarrolla su propio lenguaje. Por otro lado, estas youtubers ostentan una autenticidad más reflexiva (Giddens, 1994 y más comprometida que la de las representaciones posfeministas, generalmente vacías de contenido pol

  6. Nuclear materials control technology in the post-cold war world: Radiation-based methods and information management systems

    Energy Technology Data Exchange (ETDEWEB)

    Tape, J.W.; Eccleston, G.W.; Ensslin, N.; Markin, J.T.

    1993-06-01

    The end of the cold war is providing both opportunities and requirements for improving the control of nuclear materials around the world. The dismantlement of nuclear weapons and the growth of nuclear power, including the use of plutonium in light water reactors and breeder reactor programs, coupled with enhanced proliferation concerns, drive the need for improved nuclear materials control. We describe nuclear materials control and the role of technology in making controls more effective and efficient. The current use and anticipated development in selected radiation-based methods and related information management systems am described briefly.

  7. Subdural hematoma (SDH): assessment of macrophage reactivity within the dura mater and underlying hematoma.

    Science.gov (United States)

    Al-Sarraj, S; Mohamed, S; Kibble, M; Rezaie, P

    2004-01-01

    Macrophages are an inherent component of the dura mater, and can be characterised in cases of subdural hematoma (SDH) by their progressive and varying accumulation within areas of damage. Gross and histological methods used to determine the age of SDH are inexact. These are in part due to the active nature of such lesions and the diverse manner in which trauma victims respond to injury. Correct diagnosis has obvious medico-legal implications. However, there is as yet no specific diagnostic method that allows the age of SDH to be reliably determined. This study investigated the progressive and orderly pattern of reactivity of resident and infiltrating dural macrophages that occurs in response to injury associated with SDH. 26 postmortem cases of traumatic SDH were examined with survival times (onset of trauma to death) ranging from a few hours and up to 31 days. Macrophage reactivity associated with the dura mater and the underlying hematoma was determined using CD68 and MHC class II immunohistochemistry and the qualitative and quantitative findings compared with the presence of iron detected using conventional Perl's Prussian blue method. The results show that CD68 and MHC class II are differentially expressed within the dura mater and hematoma in SDH, and that the expression of MHC class II is markedly upregulated in the inner aspect of the dura mater within the initial 24 hours following injury. CD68 expression can be detected quantitatively in the hematoma, 24-48 hours after SDH, and within the dura following this period. Linear regression analysis further revealed a significant and positive association between the expression of MHC class II or CD68 antigens and the progressive survival of SDH up to 31 days post-injury, which was not seen with Perl's histochemical method. The expression of MHC class II antigen was a distinguishing, and quantifiable feature particularly localized within the inner aspect of the dura from a very early stage in the progression of

  8. The orphan nuclear hormone receptor ERRβ controls rod photoreceptor survival

    Science.gov (United States)

    Onishi, Akishi; Peng, Guang-Hua; Poth, Erin M.; Lee, Daniel A.; Chen, Jichao; Alexis, Uel; de Melo, Jimmy; Chen, Shiming; Blackshaw, Seth

    2010-01-01

    Mutation of rod photoreceptor-enriched transcription factors is a major cause of inherited blindness. We identified the orphan nuclear hormone receptor estrogen-related receptor β (ERRβ) as selectively expressed in rod photoreceptors. Overexpression of ERRβ induces expression of rod-specific genes in retinas of wild-type as well as Nrl−/− mice, which lack rod photoreceptors. Mutation of ERRβ results in dysfunction and degeneration of rods, whereas inverse agonists of ERRβ trigger rapid rod degeneration, which is rescued by constitutively active mutants of ERRβ. ERRβ coordinates expression of multiple genes that are rate-limiting regulators of ATP generation and consumption in photoreceptors. Furthermore, enhancing ERRβ activity rescues photoreceptor defects that result from loss of the photoreceptor-specific transcription factor Crx. Our findings demonstrate that ERRβ is a critical regulator of rod photoreceptor function and survival, and suggest that ERRβ agonists may be useful in the treatment of certain retinal dystrophies. PMID:20534447

  9. Hermenéutica de la persona. Modos de reconocimiento a través de la agencia.

    Directory of Open Access Journals (Sweden)

    Francisco Guzmán Castillo

    2010-08-01

    Full Text Available El propósito de este artículo es analizar cómo y por qué reconocemos a los otros como personas plenas, y cuáles son los mecanismos sociales que justifican y permiten que algunas personas sean tratadas como objetos, de forma opresiva y discriminatoria. En mi análisis partiré de la agencia intencional como elemento necesario en cualquier modelo de construcción de la persona. Aún así, se discutirá si la intencionalidad puede considerarse como un atributo exclusivo de los humanos. Expondré tres modelos explicativos para describir la manera en que las personas se relacionan unos con otros y con el entorno. Estos modelos son: el de los tipos literarios, el del dipolo de agencia y el modelo espacial de agencia. Finalmente reivindicaré la importancia del cuerpo como instancia constitutiva del constructo persona, con una importancia igual a la de la subjetividad y la de las circunstancias ambientales. Fecha de recepción: 04 de julio de 2010. Fecha de aceptación: 10 de agosto de 2010.

  10. Hermenéutica de la persona. Modos de reconocimiento a través de la agencia.

    Directory of Open Access Journals (Sweden)

    Francisco Guzmán Castillo

    2010-08-01

    Full Text Available El propósito de este artículo es analizar cómo y por qué reconocemos a los otros como personas plenas, y cuáles son los mecanismos sociales que justifican y permiten que algunas personas sean tratadas como objetos, de forma opresiva y discriminatoria. En mi análisis partiré de la agencia intencional como elemento necesario en cualquier modelo de construcción de la persona. Aún así, se discutirá si la intencionalidad puede considerarse como un atributo exclusivo de los humanos. Expondré tres modelos explicativos para describir la manera en que las personas se relacionan unos con otros y con el entorno. Estos modelos son: el de los tipos literarios, el del dipolo de agencia y el modelo espacial de agencia. Finalmente reivindicaré la importancia del cuerpo como instancia constitutiva del constructo persona, con una importancia igual a la de la subjetividad y la de las circunstancias ambientales.

  11. Información económica de Agencias Internacionales de Noticias: Impacto en la imagen de Venezuela

    Directory of Open Access Journals (Sweden)

    Nora Martínez

    2013-01-01

    Full Text Available El presente artículo tiene como objetivo analizar la influencia de las informaciones económicas generadas por las agencias internacionales de noticias sobre la imagen de Venezuela. Para lograr este propósito, se planteó un cuerpo teórico basado en diversos autores y se desarrolló una investigación descriptiva, cuya población estuvo integrada por periódicos de América Latina inscritos en la Sociedad Interamericana de Prensa (SIP, en especial los que mantienen suscripción con las agencias internacionales de noticias; siendo las unidades de información los editores y directores de la fuente de economía de dichos diarios. Los resultados arrojaron que las informaciones que difunden las agencias internacionales de noticias en Latinoamérica influyen en la formación de la imagen de Venezuela, partiendo de que el 70% de la muestra nunca ha visitado el país y que su opinión está basada en las informaciones económicas y políticas que recibe a diario de estas empresas noticiosas.Apartir de estas reseñas se generan opiniones sobre Venezuela con un matiz político, económico y social negativo, contrario a la percepción hacia sus habitantes basada en calidez y hospitalidad y en paisajes hermosos.

  12. Processing used nuclear fuel with nanoscale control of uranium and ultrafiltration

    Energy Technology Data Exchange (ETDEWEB)

    Wylie, Ernest M.; Peruski, Kathryn M.; Prizio, Sarah E. [Department of Civil and Environmental Engineering and Earth Sciences, University of Notre Dame, Notre Dame, IN 46556 (United States); Bridges, Andrea N.A.; Rudisill, Tracy S.; Hobbs, David T. [Savannah River National Laboratory, Aiken, SC 29808 (United States); Phillip, William A. [Department of Chemical and Biomolecular Engineering, University of Notre Dame, Notre Dame, IN 46556 (United States); Burns, Peter C., E-mail: pburns@nd.edu [Department of Civil and Environmental Engineering and Earth Sciences, University of Notre Dame, Notre Dame, IN 46556 (United States); Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN 46556 (United States)

    2016-05-15

    Current separation and purification technologies utilized in the nuclear fuel cycle rely primarily on liquid–liquid extraction and ion-exchange processes. Here, we report a laboratory-scale aqueous process that demonstrates nanoscale control for the recovery of uranium from simulated used nuclear fuel (SIMFUEL). The selective, hydrogen peroxide induced oxidative dissolution of SIMFUEL material results in the rapid assembly of persistent uranyl peroxide nanocluster species that can be separated and recovered at moderate to high yield from other process-soluble constituents using sequestration-assisted ultrafiltration. Implementation of size-selective physical processes like filtration could results in an overall simplification of nuclear fuel cycle technology, improving the environmental consequences of nuclear energy and reducing costs of processing. - Highlights: • Nanoscale control in irradiated fuel reprocessing. • Ultrafiltration to recover uranyl cage clusters. • Alternative to solvent extraction for uranium purification.

  13. Export Control Guide: Loose Parts Monitoring Systems for Nuclear Power Plants

    Energy Technology Data Exchange (ETDEWEB)

    Langenberg, Donald W. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2012-12-01

    This report describes a typical LPMS, emphasizing its application to the RCS of a modern NPP. The report also examines the versatility of AE monitoring technology by describing several nuclear applications other than loose parts monitoring, as well as some non-nuclear applications. In addition, LPMS implementation requirements are outlined, and LPMS suppliers are identified. Finally, U.S. export controls applicable to LPMSs are discussed.

  14. Near-term improvements for nuclear power plant control room annunciator systems. [PWR; BWR

    Energy Technology Data Exchange (ETDEWEB)

    Rankin, W.L.; Duvernoy, E.G.; Ames, K.R.; Morgenstern, M.H.; Eckenrode, R.J.

    1983-04-01

    This report sets forth a basic design philosophy with its associated functional criteria and design principles for present-day, hard-wired annunciator systems in the control rooms of nuclear power plants. It also presents a variety of annunciator design features that are either necessary for or useful to the implementation of the design philosophy. The information contained in this report is synthesized from an extensive literature review, from inspection and analysis of control room annunciator systems in the nuclear industry and in related industries, and from discussions with a variety of individuals who are knowledgeable about annunciator systems, nuclear plant control rooms, or both. This information should help licensees and license applicants in improving their hard-wired, control room annunciator systems as outlined by NUREG-0700.

  15. Diversity Strategies for Nuclear Power Plant Instrumentation and Control Systems

    Energy Technology Data Exchange (ETDEWEB)

    Wood, Richard Thomas [ORNL; Belles, Randy [ORNL; Cetiner, Mustafa Sacit [ORNL; Holcomb, David Eugene [ORNL; Korsah, Kofi [ORNL; Loebl, Andy [ORNL; Mays, Gary T [ORNL; Muhlheim, Michael David [ORNL; Mullens, James Allen [ORNL; Poore III, Willis P [ORNL; Qualls, A L [ORNL; Wilson, Thomas L [ORNL; Waterman, Michael E. [U.S. Nuclear Regulatory Commission

    2010-02-01

    This report presents the technical basis for establishing acceptable mitigating strategies that resolve diversity and defense-in-depth (D3) assessment findings and conform to U.S. Nuclear Regulatory Commission (NRC) requirements. The research approach employed to establish appropriate diversity strategies involves investigation of available documentation on D3 methods and experience from nuclear power and nonnuclear industries, capture of expert knowledge and lessons learned, determination of best practices, and assessment of the nature of common-cause failures (CCFs) and compensating diversity attributes. The research described in this report does not provide guidance on how to determine the need for diversity in a safety system to mitigate the consequences of potential CCFs. Rather, the scope of this report provides guidance to the staff and nuclear industry after a licensee or applicant has performed a D3 assessment per NUREG/CR-6303 and determined that diversity in a safety system is needed for mitigating the consequences of potential CCFs identified in the evaluation of the safety system design features. Succinctly, the purpose of the research described in this report was to answer the question, 'If diversity is required in a safety system to mitigate the consequences of potential CCFs, how much diversity is enough?' The principal results of this research effort have identified and developed diversity strategies, which consist of combinations of diversity attributes and their associated criteria. Technology, which corresponds to design diversity, is chosen as the principal system characteristic by which diversity criteria are grouped to form strategies. The rationale for this classification framework involves consideration of the profound impact that technology-focused design diversity provides. Consequently, the diversity usage classification scheme involves three families of strategies: (1) different technologies, (2) different approaches within

  16. [A set of quality and safety indicators for hospitals of the "Agencia Valenciana de Salud"].

    Science.gov (United States)

    Nebot-Marzal, C M; Mira-Solves, J J; Guilabert-Mora, M; Pérez-Jover, V; Pablo-Comeche, D; Quirós-Morató, T; Cuesta Peredo, D

    2014-01-01

    To prepare a set of quality and safety indicators for Hospitals of the «Agencia Valenciana de Salud». The qualitative technique Metaplan® was applied in order to gather proposals on sustainability and nursing. The catalogue of the «Spanish Society of Quality in Healthcare» was adopted as a starting point for clinical indicators. Using the Delphi technique, 207 professionals were invited to participate in the selecting the most reliable and feasible indicators. Lastly, the resulting proposal was validated with the managers of 12 hospitals, taking into account the variability, objectivity, feasibility, reliability and sensitivity, of the indicators. Participation rates varied between 66.67% and 80.71%. Of the 159 initial indicators, 68 were prioritized and selected (21 economic or management indicators, 22 nursing indicators, and 25 clinical or hospital indicators). Three of them were common to all three categories and two did not match the specified criteria during the validation phase, thus obtaining a final catalogue of 63 indicators. A set of quality and safety indicators for Hospitals was prepared. They are currently being monitored using the hospital information systems. Copyright © 2013 SECA. Published by Elsevier Espana. All rights reserved.

  17. Del sujeto a la agencia (a través de lo político

    Directory of Open Access Journals (Sweden)

    José Enrique Ema López

    2004-05-01

    Full Text Available Este trabajo tiene su campo de preocupaciones en la ?trastienda? de la teorización social sobre la acción política. Y aunque tomamos como punto de partida la imposibilidad de fundamentar la acción política en el sujeto universal del Racionalismo y Humanismo moderno, pretendemos hacer compatible un conjunto de críticas a este Humanismo y Racionalismo con una apuesta y compromiso con algunas de las propuestas emancipatorias de la modernidad. Así, presentaremos dos formas de abordar las tensiones provocadas por el privilegio del sujeto de la modernidad para pensar en la política. Una de ellas se centrará en su politización radical, introduciendo al sujeto como territorio y consecuencia de la propia acción. Otra, presenta la noción de agencia como privilegio de las conexiones y los movimientos frente a las (identidades, para explicar la acción.

  18. Multi-Canister overpack pressurization monitoring and control methodology for the spent nuclear fuel project

    Energy Technology Data Exchange (ETDEWEB)

    Pajunen, A.L., Westinghouse Hanford

    1996-07-19

    A control methodology is developed and monitoring alternatives evaluated for controlling pressurization in a Multi- Canister Overpack for the Hanford Spent Nuclear Fuel Project. Monitoring alternative evaluations include concept description, identification of uncertainties, and identification of experimental work required for implementation. A monitoring alternative is recommended and implementation requirements, risks and start up testing associated with the recommendation are discussed.

  19. Control oriented modeling and simulation of the sawtooth instability in nuclear fusion tokamak plasmas

    NARCIS (Netherlands)

    Witvoet, G.; Westerhof, E.; Steinbuch, M.; Doelman, N.J.; Baar, M.R. de

    2009-01-01

    Tokamak plasmas in nuclear fusion are subject to various instabilities. A clear example is the sawtooth instability, which has both positive and negative effects on the plasma. To optimize between these effects control of the sawtooth period is necessary. This paper presents a simple control

  20. Nonlinear control for core power of pressurized water nuclear reactors using constant axial offset strategy

    Directory of Open Access Journals (Sweden)

    Gholam Reza Ansarifar

    2015-12-01

    Full Text Available One of the most important operations in nuclear power plants is load following, in which an imbalance of axial power distribution induces xenon oscillations. These oscillations must be maintained within acceptable limits otherwise the nuclear power plant could become unstable. Therefore, bounded xenon oscillation is considered to be a constraint for the load following operation. In this paper, the design of a sliding mode control (SMC, which is a robust nonlinear controller, is presented. SMC is a means to control pressurized water nuclear reactor (PWR power for the load following operation problem in a way that ensures xenon oscillations are kept bounded within acceptable limits. The proposed controller uses constant axial offset (AO strategy to ensure xenon oscillations remain bounded. The constant AO is a robust state constraint for the load following problem. The reactor core is simulated based on the two-point nuclear reactor model with a three delayed neutron groups. The stability analysis is given by means of the Lyapunov approach, thus the control system is guaranteed to be stable within a large range. The employed method is easy to implement in practical applications and moreover, the SMC exhibits the desired dynamic properties during the entire output-tracking process independent of perturbations. Simulation results are presented to demonstrate the effectiveness of the proposed controller in terms of performance, robustness, and stability. Results show that the proposed controller for the load following operation is so effective that the xenon oscillations are kept bounded in the given region.

  1. WTEC panel report on European nuclear instrumentation and controls. Final report

    Energy Technology Data Exchange (ETDEWEB)

    White, J.D.; Lanning, D.D.; Johnson, P.M.H. [eds.] [World Technology Evaluation Center, Baltimore, MD (United States); Shelton, R.D. [World Technology Evaluation Center, Baltimore, MD (United States)

    1991-12-01

    A study of instrumentation and controls (I and C) technology used in nuclear power plants in Europe was conducted by a panel of US specialists. This study plants in Europe was conducted by a panel of US specialists. This study included a review of the literature on the subject, followed by a visit to some of the leading organizations in Europe in the field nuclear I and C. Areas covered are: (1) role of the operator and control room design; (2) transition from analog to digital technology; (3) computerized operator support systems for fault management; (4) control strategies and techniques; (5) Nuclear power plant I and C architecture; (6) instrumentation and (7) computer standards and tools. The finding relate to poor reactions.

  2. Technology Roadmap Instrumentation, Control, and Human-Machine Interface to Support DOE Advanced Nuclear Energy Programs

    Energy Technology Data Exchange (ETDEWEB)

    Donald D Dudenhoeffer; Burce P Hallbert

    2007-03-01

    Instrumentation, Controls, and Human-Machine Interface (ICHMI) technologies are essential to ensuring delivery and effective operation of optimized advanced Generation IV (Gen IV) nuclear energy systems. In 1996, the Watts Bar I nuclear power plant in Tennessee was the last U.S. nuclear power plant to go on line. It was, in fact, built based on pre-1990 technology. Since this last U.S. nuclear power plant was designed, there have been major advances in the field of ICHMI systems. Computer technology employed in other industries has advanced dramatically, and computing systems are now replaced every few years as they become functionally obsolete. Functional obsolescence occurs when newer, more functional technology replaces or supersedes an existing technology, even though an existing technology may well be in working order.Although ICHMI architectures are comprised of much of the same technology, they have not been updated nearly as often in the nuclear power industry. For example, some newer Personal Digital Assistants (PDAs) or handheld computers may, in fact, have more functionality than the 1996 computer control system at the Watts Bar I plant. This illustrates the need to transition and upgrade current nuclear power plant ICHMI technologies.

  3. Nuclear weapons, scientists, and the post-Cold War challenge selected papers on arms control

    CERN Document Server

    Drell, Sidney D

    2007-01-01

    This volume includes a representative selection of Sidney Drell's recent writings and speeches (circa 1993 to the present) on public policy issues with substantial scientific components. Most of the writings deal with national security, nuclear weapons, and arms control and reflect the author's personal involvement in such issues dating back to 1960. Fifteen years after the demise of the Soviet Union, the gravest danger presented by nuclear weapons is the spread of advanced technology that may result in the proliferation of nuclear weapons. Of most concern would be their acquisition by hostile governments and terrorists who are unconstrained by accepted norms of civilized behavior. The current challenges are to prevent this from happening and, at the same time, to pursue aggressively the opportunity to escape from an outdated nuclear deterrence trap.

  4. Gestão do Capital Humano: comparação na localização de software de gestão do capital humano entre os países Brasil, Argentina e MéxicoHuman Capital Management: comparison in the location of softwares of human capital management among the countries Brazil, Argentina and MexicoGestión del Capital Humano: una comparación entre Brasil, Argentina y México con respecto a la localización del software de gestión del capital humano

    Directory of Open Access Journals (Sweden)

    DIAS, Dilson

    2009-12-01

    Full Text Available RESUMOA área de administração de pessoal iniciou, dentro das organizações, um processo que hoje é o grande foco dos investimentos na busca da competitividade de mercado, tão acirrada em tempos de forte globalização, que é a gestão do capital humano. Há algum tempo, as organizações já perceberam que o diferencial para ser competitivo não está no que se produz e sim nas pessoas que tornam tal processo uma realidade. Como se vive atualmente a era do conhecimento, os softwares de gestão do capital humano vieram para potencializar a gestão desses recursos humanos, tornando mais ágil o processo de disseminação. Tanto quanto a veloz expansão dos softwares, as empresas se estenderam para diversas regiões do planeta, o que gera a demanda de ter um software adequado às convenções locais, seja ele localizado ou não. A localização de software é uma área de estudos recentes, mas já conta com investimentos em centros de pesquisas por parte de transnacionais. Como objetivo geral da presente pesquisa, buscou-se comparar as principais informações pertinentes à área de administração de pessoal entre Brasil, Argentina e México, para a Localização de um software de gestão do capital humano, e dessa formar e inspirar outros pesquisadores a explorarem este assunto em outras áreas da Administração. A pesquisa utilizou o método comparativo. Quanto aos objetivos pode ser classificada como descritiva e exploratória; quanto aos procedimentos pode ser classificada como bibliográfica e documental; e quanto à abordagem do problema, pode ser classificada como quantitativa e qualitativa. Foram aplicados questionários estruturados em empresas da Argentina e do México, e a análise dos resultados permitiu que fosse possível identificar quais são as áreas de atuação de maior aderência nesses países, e principalmente quais são as informações de maior e menor aderência para a localização dos softwares brasileiros. O

  5. Two-pulse laser control of nuclear and electronic motion

    DEFF Research Database (Denmark)

    Grønager, Michael; Henriksen, Niels Engholm

    1997-01-01

    We discuss an explicitly time-dependent two-pulse laser scheme for controlling where nuclei and electrons are going in unimolecular reactions. We focus on electronic motion and show, with HD+ as an example, that one can find non-stationary states where the electron (with some probability) oscilla......We discuss an explicitly time-dependent two-pulse laser scheme for controlling where nuclei and electrons are going in unimolecular reactions. We focus on electronic motion and show, with HD+ as an example, that one can find non-stationary states where the electron (with some probability...

  6. Mechanical properties of dura mater from the rat brain and spinal cord.

    Science.gov (United States)

    Maikos, Jason T; Elias, Ragi A I; Shreiber, David I

    2008-01-01

    The dura mater is the outermost and most substantial meningial layer of central nervous system (CNS) tissue that acts as a protective membrane for the brain and spinal cord. In animal models of traumatic brain injury and spinal cord injury, mechanical insults are often delivered directly to the dura to injure the underlying tissue. As such, including a description of the mechanical properties of dura mater is critical for biomechanical analyses of these models. We have characterized the mechanical response of dura mater from the rat brain and spinal cord in uniaxial tension. Testing was performed at low (0.0014 sec(-1)) and high (19.42 sec(-1)) strain rates. Both rat cranial dura and spinal dura demonstrated non-linear stress-strain responses characteristic of collagenous soft tissues. The non-linear increase in stress lagged in the spinal dura compared to the cranial dura. The slow rate data was fit to a one-term Ogden hyperelastic constitutive law, and significant differences were observed for the stiffness, G, and the parameter, alpha, which nominally introduces non-linearity. High strain rate stress-relaxation tests were performed to 10% strain, which was held for 10 sec. The relaxation was fit to a four-term Prony series exponential decay. Cranial dura and spinal dura demonstrated similar overall relaxation, but significant differences were identified in the distribution of the relaxation over the Prony series parameters, which demonstrated that cranial dura tended to relax faster. Polarized light microscopy revealed that the structural entities of spinal dura were aligned in the axial direction, whereas cranial dura did not demonstrate a preferential alignment. This was confirmed qualitatively with Masson's Tri-chrome and Verhoeff's Van Gieson staining for collagen and elastin, which also indicated greater elastin content for the spinal dura than for the cranial dura.

  7. Anatomic study and clinical significance of the dorsal meningovertebral ligaments of the thoracic dura mater.

    Science.gov (United States)

    Chen, Rongzi; Shi, Benchao; Zheng, Xuefeng; Zhou, Zhilai; Jin, Anmin; Ding, Zihai; Lv, Hai; Zhang, Hui

    2015-05-15

    A dissection-based study of 18 embalmed thoracic specimens. To investigate the properties and clinical significance of the dorsal meningovertebral ligaments of the thoracic dura mater. Previously, we performed a comprehensive anatomic study on the dorsal meningovertebral ligaments in the lumbosacral and cervical regions, whereby we concluded that the ligaments were an anatomic factor leading to dural laceration and hemorrhage during flavectomy and laminectomy. Unfortunately, thus far, no systematic anatomic study has been undertaken to examine the dorsal meningovertebral ligaments of the thoracic dura mater. Eighteen adult embalmed cadavers were studied, and the morphology, orientation, attachment site, and distribution traits of the dorsal meningovertebal ligaments were observed. In addition, the length, width, or diameter and thickness of the ligaments were measured using a Vernier caliper. Two meningovertebal ligaments were removed for histological examination. In the thoracic region, the dorsal meningovertebral ligaments anchored the dura mater to the lamina or ligamentum flavum. The meningovertebral ligaments displayed a relatively even distribution along the upper thoracic region (T1-T7) and a gradual increase in frequency in the lower thoracic region from T7 to T12. The meningovertebral ligaments protrude into the dura and correspondingly become an integral part of the dura. Some ligaments are accompanied by or are attached to blood vessels. Histological examination of the meningovertebral ligaments revealed fibrous connective tissue. The dorsal meningovertebral ligaments exist between the dural sac and ligamentum flavum or lamina in the thoracic spine. Based on their anatomic features, meningovertebral ligaments may be one potential cause for dural laceration and epidural hemorrhage. We propose that, during thoracic flavectomy and laminectomy, the meningovertebral ligaments should first be identified and properly handled, thereby minimizing the occurrence

  8. KEDO LWR construction project and application of nuclear export control to the project

    Energy Technology Data Exchange (ETDEWEB)

    Kim, J. S.; Lee, J. W.; Kim, K. J.; Min, K. S.; Choi, Y. M. [KAERI, Taejon (Korea, Republic of)

    2001-10-01

    The nuclear crisis caused by the inconsistency included in DPRK's intial report to the IAEA has passed many stages such as DPRK's declaration to withdraw from NPT and rejection of the IAEA special inspection, etc. Finally, US and DPRK had singed to the Agreed Framework which has several responsibilities to be implemented by each sides. One of them is to supply 2 LWR to the DPRK in place of the freeze of graphite moderated reactors that were operating or constructing in DPRK at that time. As an implementing organization, KEDO has been established. KEPCO, the main contrator of KEDO, is constructing the KEDO Reactor unit 1 at Kumho site according to the Supply Agreement between KEDO and DPRK. It means that the nuclear items such as facilities, equipments, nuclear material and related technology have to transferred to DPRK under the domestic nuclear export control regulation. This paper is prepared to overview the KEDO LWR project with the view of export control and review on the national nuclear export control policies, license requirements, and DDCC management.

  9. Instrumentation and controls evaluation for space nuclear power systems

    Science.gov (United States)

    Anderson, J. L.; Oakes, L. C.

    Design of control and protection systems should be coordinated with the design of the neutronic, thermal-hydraulic, and mechanical aspects of the core and plant at the earliest possible stage of concept development. An integrated systematic design approach is necessary to prevent uncoordinated choices in one technology area from imposing impractical or impossible requirements in another. Significant development and qualification will be required for virtually every aspect of reactor control and instrumentation. In-core instrumentation widely used in commercial light water reactors will not likely be usable in the higher temperatures of a space power plant. Thermocouples for temperature measurement and gamma thermometers for flux measurement appear to be the only viable candidates. Recent developments in ex-core neutron detectors may provide achievable alternatives to in-core measurements. Reliable electronic equipment and high-temperature actuators will require major development efforts.

  10. Compatibility of refractory materials for nuclear reactor poison control systems

    Science.gov (United States)

    Sinclair, J. H.

    1974-01-01

    Metal-clad poison rods have been considered for the control system of an advanced space power reactor concept studied at the NASA Lewis Research Center. Such control rods may be required to operate at temperatures of about 140O C. Selected poison materials (including boron carbide and the diborides of zirconium, hafnium, and tantalum) were subjected to 1000-hour screening tests in contact with candidate refractory metal cladding materials (including tungsten and alloys of tantalum, niobium, and molybdenum) to assess the compatibility of these materials combinations at the temperatures of interest. Zirconium and hafnium diborides were compatible with refractory metals at 1400 C, but boron carbide and tantalum diboride reacted with the refractory metals at this temperature. Zirconium diboride also showed promise as a reaction barrier between boron carbide and tungsten.

  11. Proceedings of the second US Department of Energy environmental control symposium. Volume 2. Nuclear energy, conservation, and solar energy

    Energy Technology Data Exchange (ETDEWEB)

    None

    1980-06-01

    These proceedings document the presentations given at the Second Environmental Control Symposium. Symposium presentations highlighted environmental control activities which span the entire DOE. Volume II contains papers relating to: environmental control aspects of nuclear energy use and development; nuclear waste management; renewable energy sources; transportation and building conservation (fuel economy, gasohol, building standards, and industry); and geothermal energy, power transmission, and energy storage. (DMC)

  12. Multi-region fuzzy logic controller with local PID controllers for U-tube steam generator in nuclear power plant

    Directory of Open Access Journals (Sweden)

    Puchalski Bartosz

    2015-12-01

    Full Text Available In the paper, analysis of multi-region fuzzy logic controller with local PID controllers for steam generator of pressurized water reactor (PWR working in wide range of thermal power changes is presented. The U-tube steam generator has a nonlinear dynamics depending on thermal power transferred from coolant of the primary loop of the PWR plant. Control of water level in the steam generator conducted by a traditional PID controller which is designed for nominal power level of the nuclear reactor operates insufficiently well in wide range of operational conditions, especially at the low thermal power level. Thus the steam generator is often controlled manually by operators. Incorrect water level in the steam generator may lead to accidental shutdown of the nuclear reactor and consequently financial losses. In the paper a comparison of proposed multi region fuzzy logic controller and traditional PID controllers designed only for nominal condition is presented. The gains of the local PID controllers have been derived by solving appropriate optimization tasks with the cost function in a form of integrated squared error (ISE criterion. In both cases, a model of steam generator which is readily available in literature was used for control algorithms synthesis purposes. The proposed multi-region fuzzy logic controller and traditional PID controller were subjected to broad-based simulation tests in rapid prototyping software - Matlab/Simulink. These tests proved the advantage of multi-region fuzzy logic controller with local PID controllers over its traditional counterpart.

  13. Publicidad para inmigrantes en España. Un estudio desde las agencias

    Directory of Open Access Journals (Sweden)

    Antonio-J. Baladrón-Pazos

    2011-01-01

    Full Text Available En este artículo se aborda la situación actual y el futuro de la publicidad para inmigrantes en España. Se recogen los resultados de una investigación tipo Delphi realizada en 2009 y 2010 entre directivos de las agencias étnicas. El objetivo principal fue llevar a cabo un análisis sobre las tendencias que, según estos directivos, caracterizarán la publicidad para inmigrantes en los próximos años y sobre cómo realmente ellos desearían que evolucionase esta publicidad. Se reflexiona sobre la necesidad que tienen las empresas de orientar su comunicación a una sociedad cada vez más traspasada por la diversidad cultural, debido al notable crecimiento de la inmigración en la España de los últimos años. Entre las conclusiones obtenidas, destaca que en el futuro la publicidad para inmigrantes pasará por un mayor grado de creatividad, de utilización de la Web 2.0., de profesionalización del sector y de investigación sobre este segmento. También se platea como hipótesis de futuro que en esta publicidad sea cada vez menos relevante la dimensión étnica, teniendo menos importancia los referentes culturales de los orígenes de los inmigrantes. Esto será debido que los nuevos residentes estarán cada vez más integrados en la sociedad española y serán cada vez más incorporados a la planificación de todo tipo de campañas.

  14. Virtual Visit to the ATLAS Control Room by Institute of Nuclear Physics, Cracow, Poland

    CERN Multimedia

    ATLAS Experiment

    2012-01-01

    The 12 Festival of Science "Theory-knowledge-experience...". Fest will be located on the traditional Main Square, which is visited by thousands of citizens and tourists. Institute of Nuclear Physics as usual participates in this annual event. Our visitors will learn the secrets of the CERN experiments on the Large Hadron Collider - ATLAS, LHCb, ALICE, CMS, find out more about the Higgs particles, antimatter quark-gluon plasma (beeing guided by our scientists and PhD students). One of the attractions will be ATLAS Control Room Virtual Visit. Visiting people will have an opportunity to see how ATLAS is controlled and operated to collect its exciting data and ask questions to scientists and engineers involved in LHC program at CERN. Institute of Nuclear Physics has prepared also several interactive demonstrations of Atomic Force Microscopy, Magnetic Resonance, Hadron Therapy and Crystal Physics. The Institute of Nuclear Physics of the Polish Academy of Sciences carries out basic and applied research in physics, ...

  15. Dynamic nuclear polarization and optimal control spatial-selective 13C MRI and MRS

    DEFF Research Database (Denmark)

    Vinding, Mads Sloth; Laustsen, Christoffer; Maximov, Ivan I.

    2013-01-01

    Aimed at 13C metabolic magnetic resonance imaging (MRI) and spectroscopy (MRS) applications, we demonstrate that dynamic nuclear polarization (DNP) may be combined with optimal control 2D spatial selection to simultaneously obtain high sensitivity and well-defined spatial restriction. This is ach......Aimed at 13C metabolic magnetic resonance imaging (MRI) and spectroscopy (MRS) applications, we demonstrate that dynamic nuclear polarization (DNP) may be combined with optimal control 2D spatial selection to simultaneously obtain high sensitivity and well-defined spatial restriction....... This is achieved through the development of spatial-selective single-shot spiral-readout MRI and MRS experiments combined with dynamic nuclear polarization hyperpolarized [1-13C]pyruvate on a 4.7T pre-clinical MR scanner. The method stands out from related techniques by facilitating anatomic shaped region....... The technique may be important for early detection of abnormal metabolism, monitoring disease progression, and drug research....

  16. Discussion on software aging management of nuclear power plant safety digital control system.

    Science.gov (United States)

    Liang, Huihui; Gu, Pengfei; Tang, Jianzhong; Chen, Weihua; Gao, Feng

    2016-01-01

    Managing the aging of digital control systems ensures that nuclear power plant systems are in adequate safety margins during their life cycles. Software is a core component in the execution of control logic and differs between digital and analog control systems. The hardware aging management for the digital control system is similar to that for the analog system, which has matured over decades of study. However, software aging management is still in the exploratory stage. Software aging evaluation is critical given the higher reliability and safety requirements of nuclear power plants. To ensure effective inputs for reliability assessment, this paper provides the required software aging information during the life cycle. Moreover, the software aging management scheme for safety digital control system is proposed on the basis of collected aging information.

  17. Leo Szilard Lectureship Award Talk: Controlling and eliminating nuclear-weapon materials

    Science.gov (United States)

    von Hippel, Frank

    2010-02-01

    Fissile material -- in practice plutonium and highly enriched uranium (HEU) -- is the essential ingredient in nuclear weapons. Controlling and eliminating fissile material and the means of its production is therefore the common denominator for nuclear disarmament, nuclear non-proliferation and the prevention of nuclear terrorism. From a fundamentalist anti-nuclear-weapon perspective, the less fissile material there is and the fewer locations where it can be found, the safer a world we will have. A comprehensive fissile-material policy therefore would have the following elements: *Consolidation of all nuclear-weapon-usable materials at a minimum number of high-security sites; *A verified ban on the production of HEU and plutonium for weapons; *Minimization of non-weapon uses of HEU and plutonium; and *Elimination of all excess stocks of plutonium and HEU. There is activity on all these fronts but it is not comprehensive and not all aspects are being pursued vigorously or competently. It is therefore worthwhile to review the situation. )

  18. A Business Case for Nuclear Plant Control Room Modernization

    Energy Technology Data Exchange (ETDEWEB)

    Thomas, Ken [Idaho National Lab. (INL), Idaho Falls, ID (United States); Lawrie, Sean [Idaho National Lab. (INL), Idaho Falls, ID (United States); Niedermuller, Josef M. [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2016-06-01

    This paper presents a generic business case for implementation of technology that supports Control Room Modernization (CRM). The analysis presented in two forms; 1) a standalone technology upgrade, and 2) a technology upgrade that is built upon and incremental to a prior business case created for Mobile Work Packages (MWP). The business case contends that advanced communication and networking and analytical technologies will allow NPP to conduct control room operations with improved focus by reducing human factors and redundant manpower, and therefore operate with fewer errors. While some labor savings can be harvested in terms of overtime, the majority of savings are demonstrated as reduced time to take the plant off line and bring back on line in support of outages. The benefits are quantified to a rough order of magnitude that provides directional guidance to NPPs that are interested in developing a similar business case. This business case focuses on modernization of the operator control room and does not consider a complete overhaul and modernization of a plants instrument and control systems. While operators may be considering such an investment at their plants, the sizable capital investment required is not likely supported by a cost/benefit analysis alone. More likely, it is driven by obsolescence and reliability issues, and requires consideration of mechanical condition of plant systems, capital depreciation, financing, relicensing and overall viability of the plant asset over a 20-year horizon in a competitive market. Prior studies [REF] have indicated that such a modernization of plant I&C systems, alone or as part of a larger modernization effort, can yield very significant reductions in O&M costs. However, the depth of research and analysis required to develop a meaningful business case for a plant modernization effort is well beyond the scope of this study. While CRM as considered in this study can be easily integrated as part of grander plant

  19. History of the nuclear matter safety and control law; Historique de la loi sur la protection et le controle des matieres nucleaires

    Energy Technology Data Exchange (ETDEWEB)

    Dean, G.

    1994-12-31

    In this text we give the history of the law creation on the control and safety of nuclear matter. Initially based on the CEA regulation single owner of nuclear matter, the development of nuclear energy has conducted the French government to edict law in relation with IAEA and Euratom recommendations.

  20. Advanced international training course on state systems of accounting for and control of nuclear materials

    Energy Technology Data Exchange (ETDEWEB)

    1981-10-01

    This report incorporates all lectures and presentations at the Advanced International Training Course on State Systems of Accounting for and Control of Nuclear Material held April 27 through May 12, 1981 at Santa Fe and Los Alamos, New Mexico, and Richland, Washington, USA. Authorized by the US Nuclear Non-Proliferation Act and sponsored by the US Department of Energy in cooperation with the International Atomic Energy Agency, the course was developed to provide practical training in the design, implementation, and operation of a state system of nuclear materials accountability and control that satisfies both national and international safeguards. Major emphasis for the 1981 course was placed on safeguards methods used at bulk-handling facilities, particularly low-enriched uranium conversion and fuel fabrication plants. The course was conducted by the University of California's Los Alamos National Laboratory, the Battelle Pacific Northwest Laboratory, and Exxon Nuclear Company, Inc. Tours and demonstrations were arranged at both the Los Alamos National Laboratory, Los Alamos, New Mexico, and the Exxon Nuclear fuel fabrication plant, Richland, Washington.

  1. Nuclear polyhedrosis virus as a biological control agent for Malacosoma americanum (Lepidoptera: Lasiocampidae)

    Science.gov (United States)

    R.A. Progar; M.J. Rinella; D. Fekedulegn; L. Butler

    2010-01-01

    In addition to damaging trees, the eastern tent caterpillar is implicated in early fetal loss and late-term abortion in horses. In a field study, we evaluated the potential biological control of the caterpillar using eastern tent caterpillar nuclear polyhedrosis virus (ETNPV), a naturally occurring virus that is nearly species-specific. Egg masses were hatched and...

  2. Synthesis of Model Based Robust Stabilizing Reactor Power Controller for Nuclear Power Plant

    Directory of Open Access Journals (Sweden)

    Arshad Habib Malik

    2011-04-01

    Full Text Available In this paper, a nominal SISO (Single Input Single Output model of PHWR (Pressurized Heavy Water Reactor type nuclear power plant is developed based on normal moderator pump-up rate capturing the moderator level dynamics using system identification technique. As the plant model is not exact, therefore additive and multiplicative uncertainty modeling is required. A robust perturbed plant model is derived based on worst case model capturing slowest moderator pump-up rate dynamics and moderator control valve opening delay. Both nominal and worst case models of PHWR-type nuclear power plant have ARX (An Autoregressive Exogenous structures and the parameters of both models are estimated using recursive LMS (Least Mean Square optimization algorithm. Nominal and worst case discrete plant models are transformed into frequency domain for robust controller design purpose. The closed loop system is configured into two port model form and H? robust controller is synthesized. The H?controller is designed based on singular value loop shaping and desired magnitude of control input. The selection of desired disturbance attenuation factor and size of the largest anticipated multiplicative plant perturbation for loop shaping of H? robust controller form a constrained multi-objective optimization problem. The performance and robustness of the proposed controller is tested under transient condition of a nuclear power plant in Pakistan and found satisfactory.

  3. LA AGENCIA DE LA NIÑA Y EL NIÑO EN LA CONDICIÓN PRE-CIUDADANA

    Directory of Open Access Journals (Sweden)

    Marcela González Coto

    2012-01-01

    Full Text Available El presente ensayo se deriva del trabajo que recientemente han desarrollado la Fundación PANIAMOR y la Dirección General del Programa CEN-CINAI del Ministerio de Salud, sobre la formación ciudadana de los niños y las niñas costarricenses en la primera infancia. Las acciones conjuntas se han enfocado en la capacidad de agencia de los niños y las niñas, entendida como la disposición para explorar, reflexionar, actuar y valorarse en sus entornos como sujetos políticos. Para este fin, en este ensayo se lleva a cabo un análisis crítico de los modelos ideológicos y culturales que, en la sociedad contemporánea, legitiman y fomentan la condición de "pre-ciudadanía" de la infancia, mermando su desempeño, presente y futuro, como ciudadanos plenos de la sociedad. El análisis se sustenta en materiales diversos, de distintos orígenes, todos relativos a las condiciones actuales de la infancia y las formas como se restringen estas capacidades de agencia. El ensayo también aborda las dificultades y obstáculos que enfrenta un replanteamiento de las relaciones entre adultos y niños. También se documentan los esfuerzos recientes, tanto locales como internacionales, para crear marcos alternativos desde los cuales replantear la relación institucional entre unos y otros. Como principal resultado del ensayo, se delinean un conjunto de directrices, con expresión curricular, que pueden sustentar el desarrollo de las capacidades de agencia infantil con una manifestación directa en la niñez ciudadana, la cual, se plantea, se articula en tres dimensiones o ejes de desarrollo (la responsabilidad, la autonomía y el pensamiento complejo.

  4. MATER - Pianeta Terra-Mare: an interactive and multidisciplinary approach to Geosphere sciences

    Science.gov (United States)

    Piangiamore, Giovanna Lucia; Fanelli, Emanuela; Furia, Stefania; Garau, Daniela; Merlino, Silvia; Musacchio, Gemma; Carla Centineo, Maria

    2016-04-01

    Recent studies demonstrate that Earth and Marine Sciences are not properly treated in scholastic programs and in textbooks are included in a superficial way. These topics are interdisciplinary and experimental (biology, ecology, oceanography and geology) and the recent advance in these fields is strictly linked to technologic improvement. School cannot keep up with the huge advances of knowledge experimented in the last 20 years, also for the lack of didactic laboratories sufficiently updated to support experimental activities. In this context, in 2014-15 three Italian Research Institutes (INGV, ISMAR-CNR and ENEA-CRAM) have decided to support the Unified School District "ISA 10"of Lerici (Liguria, Italy) - comprehensive of kindergartner, primary and middle schools - to develop the project MATER - Pianeta Terra-Mare (Planet Earth and Sea). The acronym MATER (MARe and TERra) has also a gender value, as people involved in the projects were women, mostly researchers and teachers, which have worked side by side with other women belonging to environmental and cultural associations of the territory. This heterogeneous group has a common objective: to promote the diffusion of a scientific culture and to sensitize students from 3 to 14 years towards problems occurring in marine and terrestrial environments, fostering the settlement of a sustainable attitude to the exploitation of natural resources and consciousness to natural hazards, such as earthquakes and floods, quite common in the Ligurian region. MATER has been considered as one of the best projects funded by MIUR (Italian Ministry of Education, University and Research) inside the Dissemination of Scientific and Technological Culture call for the year 2014. Natural hazards (Planet Earth) and the chemical-physical aspects and resources of the marine environment (Planet Sea) were the two modules of the project. Planet Earth developed through Piovono Idee! (Cloudy with a chance of Ideas!), an interactive exhibition on

  5. Methodology for risk-based configuration control of nuclear power plant operation

    Energy Technology Data Exchange (ETDEWEB)

    Valle, Antonio Torres, E-mail: atorres@instec.cu [Departamento de Ingeniería Nuclear, Instituto Superior de Tecnologías y Ciencias Aplicadas, Ciudad Habana (Cuba); Oliva, Jose de Jesus Rivero, E-mail: rivero@poli.ufrj.br [Universidade Federal do Rio de Janeiro (UFRJ), RJ (Brazil). Departamento de Engenharia Nuclear

    2012-07-01

    The hazardous configurations control in Nuclear Power Plants is an application of a previous Probabilistic Safety Analysis (PSA). A more complete option would be the risk monitoring for the online detection of these configurations but expert personnel would be required to deal with the complexities of PSA and risk monitor. The paper presents a simpler but effective approach: a method of configuration control, based on dependencies matrixes. The algorithm is included in a computer code called SECURE A-Z. The configuration control is carried out in a qualitative way, without previous PSA results and not using a Risk Monitor. The simplicity of the method warrants its application to facilities where these tools have not been developed, allowing the detection of hazardous configurations during operation and increasing plant safety. This configuration control system was implemented in the Embalse Nuclear Power Plant in Argentina. The paper shows the application of the algorithm to the analysis of a simplified safety system. (author)

  6. Medios regionales y agencias de publicidad: El planificador y su decisión al elegir un medio para pautar

    OpenAIRE

    Luna Salas, Vicky

    2013-01-01

    El presente trabajo está dividido en cinco capítulos. En el primero, se define la importancia de los medios regionales en la sociedad, la necesidad de contar con publicidad como fuente de financiamiento, el problema, los objetivos y delimitaciones y los alcances de esta investigación. El segundo capítulo ubica a los medios regionales en el contexto publicitario y se definen términos como publicidad, agencia publicitaria, centrales de medios, pauta, medios de comunicación y, ent...

  7. Transformación digital y publicidad : la planificación estratégica digital en las agencias

    OpenAIRE

    Forniés Rodríguez, Alba

    2017-01-01

    La digitalització ha produït canvis en tots els departaments de les agències de publicitat. En aquest estudi s’investiga com ha afectat la transformació digital al departament de planificació estratègica, oferint una visió general de la situació actual de la planificació estratègica digital a les agències. La digitalización ha producido cambios en todos los departamentos de las agencias de publicidad. En este estudio se investiga cómo ha afectado la transformación digital en el departament...

  8. Teoría de agencia: una revisión del origen biológico del delito

    OpenAIRE

    Iván Araya; Fernando A. Crespo

    2016-01-01

    Este trabajo aborda la causa del conflicto entre principal y agente, buscando respuestas en las disciplinas de la biología, particularmente en las ciencias de la antropología criminal. Se ha realizado un ensamble entre los hallazgos de la teoría de agencia y la teoría de los delitos de cuello blanco, reinterpretando las actuaciones del agente desde su configuración entre instinto, herencia y personalidad. Los resultados en las ciencias biológicas podrían aportar nuevas interpretaciones y expl...

  9. Externalización de la gestión documental audiovisual en las televisiones por medio de productoras audiovisuales y agencias de noticias

    Directory of Open Access Journals (Sweden)

    Jorge CALDERA-SERRANO

    Full Text Available Se analiza la simplificación en el método de análisis de contenido en los archivos televisivos derivados de factores diversos tales como la reestructuración de la organización documental, los ajustes de los recursos humanos y económicos así como la adquisición de la descripción de análisis del contenido a empresas creadoras de contenidos tales como las productoras y las agencias de noticias audiovisuales. Ambos factores, de forma simbiótica, han modificado la descripción documental eliminando la descripción de contenido temático, geográfico y onomástico así como el control terminológico y documental por medio de herramientas propias del lenguaje documental. Estos cambios se traducen en graves problemas de normalización y recuperación que no parecen solventados por medio de técnicas para la identificación automática de contenido audiovisual (herramientas biométricas.

  10. Emociones, agencia y experiencia escolar: el papel de los vínculos en los procesos de inclusión escolar en el nivel secundario

    Directory of Open Access Journals (Sweden)

    Mariana Nobile

    2014-04-01

    Full Text Available Desde hace unos años venimos explorando el modo en que la dimensión emocional de la experiencia escolar interviene en los procesos de inclusión-exclusión educativa en el nivelsecundario. Aquí analizamos en profundidad las entrevistas realizadas a 16 jóvenes de sectores populares que han egresado de las llamadas “Escuelas de Reingreso” en las que se indagaron las formas en que ellos enunciaban su experiencia emocional, explorando lasfuentes de dicha emocionalidad. Respeto, entusiasmo y tranquilidad fueron lasformas enunciativas utilizadas para describir sus experiencias. Nuestra hipótesis es que el tipo de vínculos construidos con los docentes en el marco de un formato escolar particular genera una emocionalidad positiva, que permite resignificar la trayectoria escolar personal, reposicionarse frente a la institución escolar y potenciar su sensación de agencia, en términos de sentirse con mayores márgenes de control acerca de su propia vida, permitiéndole de este modo desplegar diferentes tipos de estrategias personales para su integración laboral, educativa y familiar.

  11. Control rod system useable for fuel handling in a gas-cooled nuclear reactor

    Science.gov (United States)

    Spurrier, Francis R.

    1976-11-30

    A control rod and its associated drive are used to elevate a complete stack of fuel blocks to a position above the core of a gas-cooled nuclear reactor. A fuel-handling machine grasps the control rod and the drive is unlatched from the rod. The stack and rod are transferred out of the reactor, or to a new location in the reactor, by the fuel-handling machine.

  12. The nuclear IκB family of proteins controls gene regulation and immune homeostasis.

    Science.gov (United States)

    MaruYama, Takashi

    2015-10-01

    The inhibitory IκB family of proteins is subdivided into two groups based on protein localization in the cytoplasm or in the nucleus. These proteins interact with NF-κB, a major transcription factor regulating the expression of many inflammatory cytokines, by modulating its transcriptional activity. However, nuclear IκB family proteins not only interact with NF-κB to change its transcriptional activity, but they also bind to chromatin and control gene expression. This review provides an overview of nuclear IκB family proteins and their role in immune homeostasis. Copyright © 2015 Elsevier B.V. All rights reserved.

  13. Nuclear export controls and the CTBT: Where we`ve been and challenges ahead -- Views of an engineer

    Energy Technology Data Exchange (ETDEWEB)

    Lundy, A.S.

    1998-09-01

    The paper discusses the following topics: the importance of export controls; the uniqueness of nuclear weapons and their export control requirements; ``dual-use`` controls; and recent developments in nonproliferation beyond export control. Also discussed are some non-obvious challenges which include computer modeling and visualization, and fissile material availability and instant nukes. The author concludes by asking the Nuclear Suppliers Group to consider whether there are ways to make its controls more effective.

  14. The development of radiation hardened robot for nuclear facility - Development of embedded controller for hydraulic robot

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Byung Kook; Kim, Jae Kwon [Korea Advanced Institute of Science and Technology, Taejon (Korea)

    2000-04-01

    We designed and implemented a reliable hierarchical control system for hydraulic robots for nuclear power plant maintenance. In hazardous environments such as nuclear power plants, robot systems or automated equipment should be used instead of human being for maintenance and repair. Such robot should guarantee high reliability in hazardous environments such as high radiation or high temperature. The overall system is composed of three hierarchical subsystems: i) supervisory controller in safe zone for operator interaction with monitoring and commanding and graphic user interface, ii) master controller in semi-hazardous zone for control function, and iii) slave controller in hazardous zone for sensing and actuation. These subsystems are connected with suitable communication channels: a) master-slave communication channel implemented with CAN (Control Area Network) and b) supervisory-master communication with Ethernet. The master and the slave controllers construct a feedback closed-loop control system. In order to improve reliability, the slave controller is duplicated using cold-standby scheme, and master-slave communication channel is also duplicated. The overall system is implemented harmonically, and we obtained fast control interval of 1msec, which is sufficient for high-performance real-time control. 12 refs., 58 figs., 13 tabs. (Author)

  15. Dynamic Modeling and Control Characteristics of the Two-Modular HTR-PM Nuclear Plant

    Directory of Open Access Journals (Sweden)

    Zhe Dong

    2017-01-01

    Full Text Available The modular high temperature gas-cooled reactor (MHTGR is a typical small modular reactor (SMR with inherent safety feature. Due to its high reactor outlet coolant temperature, the MHTGR can be applied not only for electricity production but also as a heat source for industrial complexes. Through multimodular scheme, that is, the superheated steam flows produced by multiple MHTGR-based nuclear supplying system (NSSS modules combined together to drive a common thermal load, the inherent safety feature of MHTGR is applicable to large-scale nuclear plants at any desired power ratings. Since the plant power control technique of traditional single-modular nuclear plants cannot be directly applied to the multimodular plants, it is necessary to develop the power control method of multimodular plants, where dynamical modeling, control design, and performance verification are three main aspects of developing plant control method. In this paper, the study in the power control for two-modular HTR-PM plant is summarized, and the verification results based on numerical simulation are given. The simulation results in the cases of plant power step and ramp show that the plant control characteristics are satisfactory.

  16. Nonlinear Coordinated Control for MHTGR-Based Nuclear Steam Supply Systems

    Science.gov (United States)

    Dong, Zhe

    2014-10-01

    Because of its inherent safety feature and potential economic competitiveness, modular high temperature gas-cooled reactor (MHTGR) has been seen as one of the best candidates for building the next generation nuclear plants. As a typical small modular reactor (SMR), MHTGR can be incorporated with new energy resources to build micro-grids, and can also be utilized to build large nuclear energy systems having inherent safety feature at any power rating. The nuclear steam supplying system (NSSS) of MHTGR-based plants is composed of an MHTGR and a once-through steam generator (OTSG). The NSSS coordinated control is crucial for providing the load-following function. Motivated by this, a nonlinear coordinated control for MHTGR-based NSSSs is proposed in this paper. Based upon theoretical analysis, sufficient conditions for this newly-built control law to guarantee globally asymptotic closed-loop stability are given. The feasibility of this novel coordinated control strategy is verified through numerical simulation, and simulation results show that this new control law can provide satisfactory regulating performance for the NSSS by properly choosing its feedback gains. Moreover, this coordinated control has a very simple form, which means that it can be easily implemented in practical engineering.

  17. Simulation of neutron multiplicity measurements using Geant4. Open source software for nuclear arms control

    Energy Technology Data Exchange (ETDEWEB)

    Kuett, Moritz

    2016-07-07

    Nuclear arms control, including nuclear safeguards and verification technologies for nuclear disarmament typically use software as part of many different technological applications. This thesis proposes to use three open source criteria for such software, allowing users and developers to have free access to a program, have access to the full source code and be able to publish modifications for the program. This proposition is presented and analyzed in detail, together with the description of the development of ''Open Neutron Multiplicity Simulation'', an open source software tool to simulate neutron multiplicity measurements. The description includes physical background of the method, details of the developed program and a comprehensive set of validation calculations.

  18. A organizaçâo contabilística no sector conserveiro entre o final do século XIX e a primeira metade do século XX: o caso Júdice Fialho = The accounting model in the Portuguese canned-fish industry between the end of the 19th century and the first...

    Directory of Open Access Journals (Sweden)

    Ana Rita Faria

    2011-12-01

    evolution of accounting practices in Portugal, namely studies based on the analysis of surviving business records of firms, justifies this study.The study concludes that, in the absence of a set of accounting principles and procedures available to all enterprises, the management of Júdice Fialho sought to adopt, from within the varied material available at the time, those accounting techniques which were most relevant to their business operations and actual needs at that time. During the period under examination, the company’s accounting records did not suffer significant changes. The formation as a partnership in 1938, four years after the death of its founder, could have acted has a stimulus for change, but that didn’t happen.Este estudo tem por objectivo analisar a organização contabilística de uma das maiores empresas da indústria de conservas de peixe portuguesa, a Júdice Fialho, entre o final do século XIX e a primeira metade do século XX. Pretende ainda confrontar a organização contabilística existente na empresa com os modelos divulgados na literatura contabilística portuguesa publicada no mesmo período.A justificação para a sua realização residiu na escassez de estudos baseados na análise de registos contabilísticos originais e na disponibilidade, no Arquivo Histórico do Museu Municipal de Portimão (Algarve, de documentação contabilística relativa a esta grande empresa. O estudo conclui que, na ausência de um conjunto de regras e princípios de Contabilidade comuns as todas as empresas, a Júdice Fialho procurou adoptar, considerando a diversidade de soluções contabilísticas divulgadas na literatura da especialidade, a mais adequada às suas características e necessidades reais. A contabilidade da empresa está organizada para fornecer informação sobre os resultados particulares de cada segmento organizacional (fábrica, secção, oficina, depósito, … e não sobre os lucros ou prejuízos obtidos na venda dos diversos produtos

  19. All-electric control of donor nuclear spin qubits in silicon

    Science.gov (United States)

    Sigillito, Anthony J.; Tyryshkin, Alexei M.; Schenkel, Thomas; Houck, Andrew A.; Lyon, Stephen A.

    2017-10-01

    The electronic and nuclear spin degrees of freedom of donor impurities in silicon form ultra-coherent two-level systems that are potentially useful for applications in quantum information and are intrinsically compatible with industrial semiconductor processing. However, because of their smaller gyromagnetic ratios, nuclear spins are more difficult to manipulate than electron spins and are often considered too slow for quantum information processing. Moreover, although alternating current magnetic fields are the most natural choice to drive spin transitions and implement quantum gates, they are difficult to confine spatially to the level of a single donor, thus requiring alternative approaches. In recent years, schemes for all-electrical control of donor spin qubits have been proposed but no experimental demonstrations have been reported yet. Here, we demonstrate a scalable all-electric method for controlling neutral 31P and 75As donor nuclear spins in silicon. Using coplanar photonic bandgap resonators, we drive Rabi oscillations on nuclear spins exclusively using electric fields by employing the donor-bound electron as a quantum transducer, much in the spirit of recent works with single-molecule magnets. The electric field confinement leads to major advantages such as low power requirements, higher qubit densities and faster gate times. Additionally, this approach makes it possible to drive nuclear spin qubits either at their resonance frequency or at its first subharmonic, thus reducing device bandwidth requirements. Double quantum transitions can be driven as well, providing easy access to the full computational manifold of our system and making it convenient to implement nuclear spin-based qudits using 75As donors.

  20. Regularity of the wear control of radioactive sources from the nuclear measurers; Regularidad del control del desgaste de fuentes radioactivas de los medidores nucleares

    Energy Technology Data Exchange (ETDEWEB)

    Ferreira L, M. [Instituto de Pesquisas Energeticas e Nucleares - IPEN-CNEN-SP, Av. Prof. Lineu Prestes 2242 - Cidade Universitaria -CEP(ZC) 05508-900, tel: (005511) 3816-9215, Sao Paulo, (Brazil)]. e-mail: mflima@ipen.br

    2006-07-01

    The control of radioactive sources in Brazil is regulated by the CNEN (National Comissao of Nuclear Energy). The Laboratory of Descontaminacao of the IPEN (Institute of Energy Y Nuclear Investigations) it offers to the companies that work with nuclear measurers, essays for control of the source wear according to the ISO 9978/1992 through the smear tests Y of leakage. The analyses are taken in alpha Y beta detectors of low bottom radiation with annual detection limits around 1 Bq. Certificates of the accepted analyses by the CNEN for sources that already passed its time of validity assured by the makers, but its continue operational are emitted. The smear test is repeated the whole year, while the leakage test repeats to every two years. A balance of the last two years of the activities of the laboratory shows the regularity of the clients Y the growth of companies specialized in radioprotection with official of radioprotection, credited by the regulatory authority that its act as intermediaries in the process, contacting the clients, gathering the samples next to the proprietors of sources Y hiring our services. Overalls, proves that the inspection activities by part of the regulatory authority are fulfil. In 2004, 192 sources were analyzed by the smear method Y 86 sources by leakage. In 2005, 232 sources were analyzed by the smear method Y 60 sources by leakage. All the leakage tests was made in sources of Americium of oneself Y only client that brings the sources so that they dismantle them to him in the Sources production laboratory of the IPEN. By the quantity Y age of the sources that were analyzed in those two years, it is proven that the number of sources without use conditions (total activity measured by the two added methods smaller than 180Bq) it doesn't arrive to 2%. (Author)

  1. The antimigraine drug, sumatriptan (GR43175), selectively blocks neurogenic plasma extravasation from blood vessels in dura mater.

    OpenAIRE

    Buzzi, M. G.; Moskowitz, M. A.

    1990-01-01

    1. We describe the actions of GR43175, a 5-hydroxytryptamine1 (5-HT1)-like receptor agonist, on neurogenically-mediated plasma protein extravasation within an important pain-sensitive intracranial tissue, the dura mater. 2. GR43175 markedly attenuated extravasation of 125I-albumin from blood vessels within ipsilateral dura mater when administered to rats (100 micrograms kg-1) fifteen minutes before unilateral electrical trigeminal stimulation (1.2 mA, 5 Hz, 5 ms, 5 min); the ratio (stimulated...

  2. Nuclear Technology Requires Control by the People, anywhere on Our Planet.

    Science.gov (United States)

    Synek, Miroslav

    2000-03-01

    ------- Human society on our planet, in its historical development, utilizing the knowledge of physics, has reached a powerful technology of nuclear intercontinental ballistic missiles, conceivably controllable through a computerized "push-button". Whenever this technology falls under the control of an irresponsible , miscalculating, or, insane, DICTATOR, with powerful means of a mass-produced nuclear built-up, anywhere on our planet, the very survival of all humanity on our planet could be threatened. --- Therefore, it is a historical urgency that this technology is under the control by a government of the people, by the people and for the people, based on a sufficiently secure system of FREE ELECTIONS, in any country on our planet, wherever and whenever such a threatening possibility exists.

  3. Analysis results for the stereotypes regarding colors applied to the nuclear power plant control room

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jung Woon; Oh, In Seok; Lee, Yong Hee; Lee, Hyun Chul [KAERI, Taejon (Korea, Republic of); Lee, Dhong Ha [Suwon Univ., Suwon (Korea, Republic of)

    2003-01-01

    The general public not engaged in the nuclear power plant industry have no idea of the color usage in the nuclear control room. So we converted the specific color usage situation into similar but general situations. In questionnaire, we gave subjects the general situation where color coding is applied and alternative colors which were applied to the HF010 guidelines. And we asked the subjects to choose the colors proper to the situation and to rank the colors according to the degree of suitability. Two hundred fifty college students participated in the experiment. The results suggest that we can use any color coding system in the conventional control room and the CRT in the control deck because most people have no special previous color-meaning association but red-emergency relation.

  4. Revision of criteria for foodstuffs control following a nuclear or radiological emergency

    Energy Technology Data Exchange (ETDEWEB)

    Park, Sang Hyun; Lee, Young Min; Jeong, Seung Young [Korea Institute of Nuclear Safety, Daejeon (Korea, Republic of)

    2015-10-15

    GAL(generic action level)s were derived using cost-benefit methods. But the factors used to derive GALs, such as Gross National Product (GNP) and cost of foodstuff, have been changed for last 10 years. Moreover the standards did not consider exposure situation change from emergency exposure to existing exposure situation. In this study, two ways to revise existing standards for foodstuff control were considered; 1st, revision of GAL, 2nd, newly derived reference level. In this study, two methods to revise food control criteria following nuclear emergency were suggested. GAL based on recent GNI and cost of foodstuff would be revised and decreased up to 30 % than existing criteria. DRLs reflecting exposure situation and consumption pattern were smaller than existing criteria for group 1 nuclides. The approach considered in the study would be applied to set up domestic criteria for food control during and following nuclear or radiological emergency.

  5. El Contrato de Agencia Comercial y los Cambios Introducidos en la Negociación del TLC Entre EE.UU. y los Países Andinos

    Directory of Open Access Journals (Sweden)

    Adriana López

    2011-07-01

    Full Text Available Tomando en consideración que dentro del tratado de libre comercio entre los Países Andinos y los Estados Unidos, se negociaron algunos cambios importantes en la regulación sobre el contrato de agencia comercial, ésta investigación tiene como objetivo principal, mostrar cuales fueron los puntos negociados por los Estados Unidos y por Colombia para este contrato, y exponer cuáles serán los cambios que el Congreso colombiano tendrá que introducir al Código de Comercio, en materia de agencia comercial.

  6. Field control of single x-ray photons in nuclear forward scattering

    CERN Document Server

    Kong, Xiangjin; Pálffy, Adriana

    2013-01-01

    Means to coherently control single x-ray photons in resonant scattering of light off nuclei by electric or magnetic fields are investigated theoretically. In order to derive the time response in nuclear forward scattering, we adapt the Maxwell-Bloch equations known from quantum optics to describe the resonant light pulse propagation through a nuclear medium. Two types of time-dependent perturbations of nuclear forward scattering are considered for coherent control of the resonantly scattered x-ray quanta. First, the simultaneous coherent propagation of two pulses through the nuclear sample is addressed. We find that the signal of a weak pulse can be enhanced or suppressed by a stronger pulse simultaneously propagating through the sample in counter-propagating geometry. Second, the effect of a time-dependent hyperfine splitting is investigated and we put forward a scheme that allows parts of the spectrum to be shifted forward in time. This is the inverse effect of coherent photon storage and may become a valua...

  7. Developing a taxonomy of coordination behaviours in nuclear power plant control rooms during emergencies.

    Science.gov (United States)

    Wang, Dunxing; Gao, Qin; Li, Zhizhong; Song, Fei; Ma, Liang

    2017-12-01

    This study aims to develop a taxonomy of coordination behaviours during emergencies in nuclear power plants (NPPs). We summarised basic coordination behaviours from literature in aviation, health care and nuclear field and identified coordination behaviours specific to the nuclear domain by interviewing and surveying control crew operators. The established taxonomy includes 7 workflow stages and 24 basic coordination behaviours. To evaluate the reliability and feasibility of the taxonomy, we analysed 12 videos of operators' training sessions by coding coordination behaviours with the taxonomy and the inter-rater reliability was acceptable. Further analysis of the frequency, the duration and the direction of the coordination behaviours revealed four coordination problems. This taxonomy provides a foundation of systematic observation of coordination behaviours among NPP crews, advances researchers' understanding of the coordination mechanism during emergencies in NPPs and facilitate the possibility to deepen the understanding of the relationships between coordination behaviours and team performance. Practitioner Summary: A taxonomy of coordination behaviours during emergencies in nuclear power plants was developed. Reliability and feasibility of the taxonomy was verified through the analysis of 12 training sessions. The taxonomy can serve as an observation system for analysis of coordination behaviours and help to identify coordination problems of control crews.

  8. La rehabilitación de un ícono de la modernidad la Iglesia Mater Misericordiae = The rehabilitation of an icon of modernity the Church Mater Misericordiae

    Directory of Open Access Journals (Sweden)

    María Belén Gómez

    2017-12-01

    Full Text Available La iglesia Mater Misericordiae es un edificio sacro levantado en Baranzate (Milán a finales de la década de los años 50.Supone la culminación de una serie de experiencias que pretendían la renovación de la liturgia y, con ello, la renovación de laarquitectura. Su construcción, enmarcada dentro de un plan más amplio acometido por el Arzobispado de Milán, supuso un gran avance en varios campos relacionados, principalmente, con la modernidad de la arquitectura sacra, la construcción y las nuevas tecnologías. Incorpora el uso no solamente del hormigón, material poco utilizado hasta ese momento en construcciones sacras, sino que, además, introduce un sistema de prefabricación y postesado “In situ” para la ejecución de la estructura que muestra el interés de los técnicos de la época por hallar nuevos medios de sistematización de la construcción. El sistema constructivo de cerramiento utilizado permite delimitar el espacio litúrgico mediante una piel translúcida que rodea el espacio, permitiendo la entrada de luz natural durante el día y la iluminación del entorno durante la noche. La presente investigación trata sobre las diferentes soluciones que se han empleado en la resolución de las fachadas de cerramiento, haciendo especial hincapié en la solución utilizada en la última rehabilitación a la que ha sido sometida. En este caso se han tratado de incorporar las tecnologías modernas más avanzadas para la resolución de los problemas que esta presentaba pero respetando al máximo la idea del proyecto original. Abstract The church Mater Misericordiae is a sacred building raised in Baranzate (Milan at the end of the decade of the 50s. It supposes the culmination of a series of experiences that were claiming the renovation of the liturgy and, with it, the renovation of the architecture. His construction, framed within a broader plan undertaken by the Archbishopric of Milan, supposed a great advance in several fields

  9. Applying Human Factors Evaluation and Design Guidance to a Nuclear Power Plant Digital Control System

    Energy Technology Data Exchange (ETDEWEB)

    Thomas Ulrich; Ronald Boring; William Phoenix; Emily Dehority; Tim Whiting; Jonathan Morrell; Rhett Backstrom

    2012-08-01

    The United States (U.S.) nuclear industry, like similar process control industries, has moved toward upgrading its control rooms. The upgraded control rooms typically feature digital control system (DCS) displays embedded in the panels. These displays gather information from the system and represent that information on a single display surface. In this manner, the DCS combines many previously separate analog indicators and controls into a single digital display, whereby the operators can toggle between multiple windows to monitor and control different aspects of the plant. The design of the DCS depends on the function of the system it monitors, but revolves around presenting the information most germane to an operator at any point in time. DCSs require a carefully designed human system interface. This report centers on redesigning existing DCS displays for an example chemical volume control system (CVCS) at a U.S. nuclear power plant. The crucial nature of the CVCS, which controls coolant levels and boration in the primary system, requires a thorough human factors evaluation of its supporting DCS. The initial digital controls being developed for the DCSs tend to directly mimic the former analog controls. There are, however, unique operator interactions with a digital vs. analog interface, and the differences have not always been carefully factored in the translation of an analog interface to a replacement DCS. To ensure safety, efficiency, and usability of the emerging DCSs, a human factors usability evaluation was conducted on a CVCS DCS currently being used and refined at an existing U.S. nuclear power plant. Subject matter experts from process control engineering, software development, and human factors evaluated the DCS displays to document potential usability issues and propose design recommendations. The evaluation yielded 167 potential usability issues with the DCS. These issues should not be considered operator performance problems but rather opportunities

  10. Measuring Human Performance in Simulated Nuclear Power Plant Control Rooms Using Eye Tracking

    Energy Technology Data Exchange (ETDEWEB)

    Kovesdi, Casey Robert [Idaho National Lab. (INL), Idaho Falls, ID (United States); Rice, Brandon Charles [Idaho National Lab. (INL), Idaho Falls, ID (United States); Bower, Gordon Ross [Idaho National Lab. (INL), Idaho Falls, ID (United States); Spielman, Zachary Alexander [Idaho National Lab. (INL), Idaho Falls, ID (United States); Hill, Rachael Ann [Idaho National Lab. (INL), Idaho Falls, ID (United States); LeBlanc, Katya Lee [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2015-11-01

    Control room modernization will be an important part of life extension for the existing light water reactor fleet. As part of modernization efforts, personnel will need to gain a full understanding of how control room technologies affect performance of human operators. Recent advances in technology enables the use of eye tracking technology to continuously measure an operator’s eye movement, which correlates with a variety of human performance constructs such as situation awareness and workload. This report describes eye tracking metrics in the context of how they will be used in nuclear power plant control room simulator studies.

  11. Mater Nostra: The Anti-blasphemy Message of the Feminist Punk-Prayer

    Directory of Open Access Journals (Sweden)

    Elena Ivanovna Volkova

    2014-12-01

    Full Text Available In this essay I develop a blasphemy counter-discourse arguing that it was ecclesial and state authorities who committed blasphemies, which were condemned by Pussy Riot’s punk-prayer. Thus, the performance in this respect may be interpreted as an anti-blasphemy protest. The blasphemy list includes the collaboration of the church with the authoritarian state, known as heresy of Sergianism; Caesar and Temple idolatry, blasphemy against the Holy Spirit, Virgin Mary and Folly for Christ’s sake. The punk-prayer may be interpreted as a feminine version of the Lord’s Prayer – Mater Nostra. Several corporeal narratives in the background – women’s dress code and rape debates, Virgin Mary’s belt, and its alleged miraculous ability to help women to deliver a baby – may be seen as allegories of feminist vs. patriarchal opposition in Russian religious and political culture.

  12. INDUSTRIAL CONTROL SYSTEM CYBER SECURITY: QUESTIONS AND ANSWERS RELEVANT TO NUCLEAR FACILITIES, SAFEGUARDS AND SECURITY

    Energy Technology Data Exchange (ETDEWEB)

    Robert S. Anderson; Mark Schanfein; Trond Bjornard; Paul Moskowitz

    2011-07-01

    Typical questions surrounding industrial control system (ICS) cyber security always lead back to: What could a cyber attack do to my system(s) and; how much should I worry about it? These two leading questions represent only a fraction of questions asked when discussing cyber security as it applies to any program, company, business, or organization. The intent of this paper is to open a dialog of important pertinent questions and answers that managers of nuclear facilities engaged in nuclear facility security and safeguards should examine, i.e., what questions should be asked; and how do the answers affect an organization's ability to effectively safeguard and secure nuclear material. When a cyber intrusion is reported, what does that mean? Can an intrusion be detected or go un-noticed? Are nuclear security or safeguards systems potentially vulnerable? What about the digital systems employed in process monitoring, and international safeguards? Organizations expend considerable efforts to ensure that their facilities can maintain continuity of operations against physical threats. However, cyber threats particularly on ICSs may not be well known or understood, and often do not receive adequate attention. With the disclosure of the Stuxnet virus that has recently attacked nuclear infrastructure, many organizations have recognized the need for an urgent interest in cyber attacks and defenses against them. Several questions arise including discussions about the insider threat, adequate cyber protections, program readiness, encryption, and many more. These questions, among others, are discussed so as to raise the awareness and shed light on ways to protect nuclear facilities and materials against such attacks.

  13. Control Systems for a Dynamic Multi-Physics Model of a Nuclear Hybrid Energy System

    Energy Technology Data Exchange (ETDEWEB)

    Greenwood, Michael Scott [ORNL; Fugate, David W [ORNL; Cetiner, Sacit M [ORNL

    2017-01-01

    A Nuclear Hybrid Energy System (NHES) uses a nuclear reactor as the basic power generation unit, and the power generated is used by multiple customers as either thermal power, electrical power, or both. The definition and architecture of a particular NHES can be adapted based on the needs and opportunities of different local markets. For example, locations in need of potable water may be best served by coupling a desalination plant to the NHES. Similarly, a location near oil refineries may have a need for emission-free hydrogen production. Using the flexible, multi-domain capabilities of Modelica, Argonne National Laboratory, Idaho National Laboratory, and Oak Ridge National Laboratory are investigating the dynamics (e.g., thermal hydraulics and electrical generation/consumption) and cost of a hybrid system. This paper examines the NHES work underway, emphasizing the control system developed for individual subsystems and the overall supervisory control system.

  14. Simulation and Automation of Microwave Frequency Control in Dynamic Nuclear Polarization for Solid Polarized Targets

    Science.gov (United States)

    Perera, Gonaduwage; Johnson, Ian; Keller, Dustin

    2017-09-01

    Dynamic Nuclear Polarization (DNP) is used in most of the solid polarized target scattering experiments. Those target materials must be irradiated using microwaves at a frequency determined by the difference in the nuclear Larmor and electron paramagnetic resonance (EPR) frequencies. But the resonance frequency changes with time as a result of radiation damage. Hence the microwave frequency should be adjusted accordingly. Manually adjusting the frequency can be difficult, and improper adjustments negatively impact the polarization. In order to overcome these difficulties, two controllers were developed which automate the process of seeking and maintaining the optimal frequency: one being a standalone controller for a traditional DC motor and the other a LabVIEW VI for a stepper motor configuration. Further a Monte-Carlo simulation was developed which can accurately model the polarization over time as a function of microwave frequency. In this talk, analysis of the simulated data and recent improvements to the automated system will be presented. DOE.

  15. Production of an English/Russian glossary of terminology for nuclear materials control and accounting

    Energy Technology Data Exchange (ETDEWEB)

    Schachowskoj, S.; Smith, H.A. Jr.

    1995-05-01

    The program plans for Former Soviet Union National Nuclear Materials Control and Accounting (MC and A) Systems Enhancements call for the development of an English/Russian Glossary of MC and A terminology. This glossary was envisioned as an outgrowth of the many interactions, training sessions, and other talking and writing exercises that would transpire in the course of carrying out these programs. This report summarizes the status of the production of this glossary, the most recent copy of which is attached to this report. The glossary contains over 950 terms and acronyms associated with nuclear material control and accounting for safeguards and nonproliferation. This document is organized as follows: English/Russian glossary of terms and acronyms; Russian/English glossary of terms and acronyms; English/Russian glossary of acronyms; and Russian/English glossary of acronyms.

  16. Instrumentation and Control Needs for Reliable Operation of Lunar Base Surface Nuclear Power Systems

    Science.gov (United States)

    Turso, James; Chicatelli, Amy; Bajwa, Anupa

    2005-01-01

    As one of the near-term goals of the President's Vision for Space Exploration, establishment of a multi-person lunar base will require high-endurance power systems which are independent of the sun, and can operate without replenishment for several years. These requirements may be obtained using nuclear power systems specifically designed for use on the lunar surface. While it is envisioned that such a system will generally be supervised by humans, some of the evolutions required maybe semi or fully autonomous. The entire base complement for near-term missions may be less than 10 individuals, most or all of which may not be qualified nuclear plant operators and may be off-base for extended periods thus, the need for power system autonomous operation. Startup, shutdown, and load following operations will require the application of advanced control and health management strategies with an emphasis on robust, supervisory, coordinated control of, for example, the nuclear heat source, energy conversion plant (e.g., Brayton Energy Conversion units), and power management system. Autonomous operation implies that, in addition to being capable of automatic response to disturbance input or load changes, the system is also capable of assessing the status of the integrated plant, determining the risk associated with the possible actions, and making a decision as to the action that optimizes system performance while minimizing risk to the mission. Adapting the control to deviations from design conditions and degradation due to component failures will be essential to ensure base inhabitant safety and mission success. Intelligent decisions will have to be made to choose the right set of sensors to provide the data needed to do condition monitoring and fault detection and isolation because of liftoff weight and space limitations, it will not be possible to have an extensive set of instruments as used for earth-based systems. Advanced instrumentation and control technologies will be

  17. Nonlinear Adaptive Dynamic Output-Feedback Power-Level Control of Nuclear Heating Reactors

    Directory of Open Access Journals (Sweden)

    Zhe Dong

    2013-01-01

    Full Text Available Due to the high safety performance of small nuclear reactors, there is a promising future for small reactors. Nuclear heating reactor (NHR is a small reactor that has many advanced safety features such as the integrated arrangement, natural circulation at any power levels, self-pressurization, hydraulic control rod driving, and passive residual heating removing and can be applied to the fields of district heating, seawater desalination, and electricity production. Since the NHR dynamics has strong nonlinearity and uncertainty, it is meaningful to develop the nonlinear adaptive power-level control technique. From the idea of physically based control design method, a novel nonlinear adaptive power-level control is given for the NHR in this paper. It is theoretically proved that this newly built controller does not only provide globally asymptotic closed-loop stability but is also adaptive to the system uncertainty. Numerical simulation results show the feasibility of this controller and the relationship between the performance and controller parameters.

  18. Baseline Evaluations to Support Control Room Modernization at Nuclear Power Plants

    Energy Technology Data Exchange (ETDEWEB)

    Boring, Ronald L.; Joe, Jeffrey C.

    2015-02-01

    For any major control room modernization activity at a commercial nuclear power plant (NPP) in the U.S., a utility should carefully follow the four phases prescribed by the U.S. Nuclear Regulatory Commission in NUREG-0711, Human Factors Engineering Program Review Model. These four phases include Planning and Analysis, Design, Verification and Validation, and Implementation and Operation. While NUREG-0711 is a useful guideline, it is written primarily from the perspective of regulatory review, and it therefore does not provide a nuanced account of many of the steps the utility might undertake as part of control room modernization. The guideline is largely summative—intended to catalog final products—rather than formative—intended to guide the overall modernization process. In this paper, we highlight two crucial formative sub-elements of the Planning and Analysis phase specific to control room modernization that are not covered in NUREG-0711. These two sub-elements are the usability and ergonomics baseline evaluations. A baseline evaluation entails evaluating the system as-built and currently in use. The usability baseline evaluation provides key insights into operator performance using the control system currently in place. The ergonomics baseline evaluation identifies possible deficiencies in the physical configuration of the control system. Both baseline evaluations feed into the design of the replacement system and subsequent summative benchmarking activities that help ensure that control room modernization represents a successful evolution of the control system.

  19. Reflected kinetics model for nuclear space reactor kinetics and control scoping calculations

    Energy Technology Data Exchange (ETDEWEB)

    Washington, K.E.

    1986-05-01

    The objective of this research is to develop a model that offers an alternative to the point kinetics (PK) modelling approach in the analysis of space reactor kinetics and control studies. Modelling effort will focus on the explicit treatment of control drums as reactivity input devices so that the transition to automatic control can be smoothly done. The proposed model is developed for the specific integration of automatic control and the solution of the servo mechanism problem. The integration of the kinetics model with an automatic controller will provide a useful tool for performing space reactor scoping studies for different designs and configurations. Such a tool should prove to be invaluable in the design phase of a space nuclear system from the point of view of kinetics and control limitations.

  20. Quality control in nuclear fuel fabrication on the inspection basis; Control de calidad para fabricacion de combustible nuclear en base a inspecciones

    Energy Technology Data Exchange (ETDEWEB)

    Fuentes S, A. [Instituto Tecnologico de Toluca, Toluca (Mexico)

    1997-12-31

    Every plant productive of electric power requires the use of energetics for the transformation to electricity. In the nucleo electric plant the energetic is the uranium, in which it makes ensembles and is used as fuel in the reactor. To assure that the fuel ensembles fulfill the specifications and requirements of design stipulated in the nucleo electric plant is that under a quality control through inspections during the fabrication process. The purpose of this work is to study and verify that the lineaments of the standard 10 CFR 50 appendix B `Quality assurement for nuclear plants` specially in the criteria `Inspections` that is used to guarantee the quality of the ensembles. This standard is the one that rules every activity and operation inside the pilot plant and its established in the quality program in the production of nuclear fuel for the Laguna Verde plant. The quality of the assemble is verified through each one of the tests or inspections due to the importance of it in the fabrication of fuel. (Author)

  1. To control the nuclear safety and the radiation protection; Controler la surete nucleaire et la radioprotection

    Energy Technology Data Exchange (ETDEWEB)

    Lacoste, A.C. [Direction Generale de la Surete Nucleaire et de la Radioprotection, 75 - Paris (France); Bordarier, Ph. [Autorite de Surete Nucleaire (ASN), 75 - Paris (France); Saint-Raymond, Ph. [Conseil General des Mines, 75 - Paris (France); Repussard, J. [Institut de Radioprotection et de Surete Nucleaire (IRSN), 92 - Clamart (France); Gouze, J.R. [Apave Groupe, 75 - Paris (France); Degos, L. [Haute Autorite de Sante, 93 - Saint-Denis La Plaine (France); Massart, S.; Wiroth, P.; Thezee, Ch.; Petit, G. [Electricite de France (EDF), 75 - Paris (France); Cahen, B.; Hubert, I.; Wiroth, P.; Thezee, Ch.; Petit, G. [Ministere de l' Ecologie et du Developpement Durable, Direction de la Prevention des Pollutions et des Risques (DPPR), 75 - Paris (France); Kaufer, B. [Organisation for Economic Co-Operation and Development, Nuclear Energy Agency (AEN/OCDE), 75 - Paris (France); Taniguchi, T. [Agence Internationale de l' Energie Atomique (AIEA), Vienna (Austria); Revol, H. [Office Parlementaire d' Evaluation des Choix Scientifiques et Technologiques (OPECST), 75 - Paris (France)

    2005-10-15

    Publishing this dossier, the aim is to present the principles and the variety of issues linked to nuclear safety and radiation protection supervision, and the main strategic choices made to use efficiently and effectively A.S.N. supervision means. A.S.N. is responsible for nuclear safety and radiation protection supervision. A.S.N. has to be itself evaluated and supervised by external bodies. The Parliament Office for Evaluation of Scientific and Technological Options (O.P.E.C.S.T.) supervises it; the foreign peers watch and A.S.N. has to be the object of an international audit conducted by its peers under the leadership of I.A.E.A. by the beginning of 2007. (N.C.)

  2. Muusikapassioon mõttepeeglis. Täna kõlab "Stabat Mater" / Anne Peäske

    Index Scriptorium Estoniae

    Peäske, Anne, 1946-

    2005-01-01

    Arvo Pärdi "Passio" ettekandest 11.sept. Rakvere Kolmainu kirikus. Elmo Lööve, Raivo Palmaru, Jaan Rääts, Toivo Tulev, Aarne Talvik, Ingmar Kurg, Olev Oja ja Eleonora Pärt Arvo Pärdi muusikast. A. Pärdi "Stabat Mater" ansambli Theatre of Voices esituses 14. sept. Rakvere Kolmainu kirikus

  3. The Mater-Bi® biodegradable film for strawberry (Fragaria x ananassa Duch. mulching: effects on fruit yield and quality

    Directory of Open Access Journals (Sweden)

    Luigi Morra

    2016-08-01

    Full Text Available Two trials in different agricultural farms were carried out from October 2014 to June 2015 with the aim to assess the advantages linked to the substitution of the low density polyethylene (LDPE films for soil mulching with the Mater-Bi® biodegradable films in the strawberry cultivation under tunnel in Campania. Lifetime of biodegradable mulch and influence of type of mulch on the yield and the quality of cvs Sabrina and Fortuna were evaluated. Plants were cultivated on mulched, raised beds, high 40 cm from bottom soil. Mater-Bi® film was 20 µm thick while LDPE film was 50 mm thick. The physical-chemical parameters (firmness, pH, total soluble solid content, titratable acidity and skin colour and some bioactive compounds (total polyphenols, flavonoids, anthocyanins, antioxidant activity of fruits were determined by three samplings effected in consecutive months (from March to May 2015 of the harvest cycle. Biodegradable film guaranteed an effective mulch along the whole strawberry cycle (9-10 months including the time of drawing up of film. Yields of cv Sabrina on LDPE was 18% higher than those on Mater-Bi® while the opposite was detected in cv Fortuna (+10%. The physical-chemical parameters of fruits were not modified by the mulches. The content of the bioactive compounds, instead, resulted, in each time of sampling, significantly higher in fruits picked on Mater-Bi® based film.

  4. Vacuum-assisted closure of necrotic and infected cranial wound with loss of dura mater: A technical note.

    Science.gov (United States)

    Ahmed, Osama; Storey, Christopher M; Zhang, Shihao; Chelly, Marjorie R; Yeoh, Melvin S; Nanda, Anil

    2015-01-01

    Complex cranial wounds can be a problematic occurrence for surgeons. Vacuum-assisted closure devices have a wide variety of applications and have recently been used in neurosurgical cases involving complex cranial wounds. There is only one report regarding the use of a vacuum-assisted closure device with loss of dura mater. We report a complicated case of a necrotic cranial wound with loss of dura mater. A 68-year-old female underwent an evacuation of a subdural hematoma. Postoperatively, the patient developed a wound infection that required removal of the bone flap. The wound developed a wedge-shaped necrosis of the scalp with exposure of brain tissue due to loss of dura mater from previous surgeries. She underwent debridement and excision of the necrotic tissue with placement of a synthetic dural graft (Durepair®, Medtronic, Inc.) and placement of a wound vac. The patient underwent a latissismus dorsi muscle flap reconstruction that subsequently failed. After the wound vac was replaced, the synthetic dural graft was replaced with a fascia lata graft and an anterolateral thigh free flap reconstruction. We describe the technical nuances of this complicated case, how the obstacles were handled, and the literature that discusses the utility. We describe a case of a complex cranial wound and technical nuances on how to utilize a wound-vac with loss of dura mater.

  5. [A case of cavernous angioma at the convexity in the dura mater: characteristics of images in the literature].

    Science.gov (United States)

    Yonezawa, Ushio; Ikawa, Fusao; Hamasaki, Osamu; Hidaka, Toshikazu; Kurokawa, Yasuharu; Onuma, Hideyuki

    2014-08-01

    We describe a rare case of cavernous angioma in the dura mater and discuss published MRI findings on similar cases. The patient was a 78-year-old woman who was referred to Shimane Prefectural Central Hospital with complaints of headaches. We were subsequently able to identify a tumor at the convexity in the dura mater. The tumor showed a high intensity on T2-weighted images and was heterogeneously enhanced on contrast-enhanced T1-weighted images. The maximum size of the tumor was 35 mm. Moreover, preoperative angiography showed a slight vascularity in the tumor. We performed surgery with the expectation of finding a meningioma, metastatic brain tumor, or another mesenchymal tumor. The tumor was dark and red, attached to the dura mater, and adhered to the arachnoid. However, we were able to peel the tumor away from the meninges and achieved a total removal of the mass, successfully cutting a fine feeding cortical artery. The patient was discharged without neurological defects 9 days after surgery;the pathological diagnosis was cavernous angioma. In conclusion, it is difficult to discern between meningioma and cavernous angioma in the dura mater. However, the specificity of high intensity on T2-weighted images is relatively high, and preoperative diagnosis can be determined by MRI and angiography findings.

  6. A HUMAN FACTORS META MODEL FOR U.S. NUCLEAR POWER PLANT CONTROL ROOM MODERNIZATION

    Energy Technology Data Exchange (ETDEWEB)

    Joe, Jeffrey C.

    2017-03-01

    Over the last several years, the United States (U.S.) Department of Energy (DOE) has sponsored human factors research and development (R&D) and human factors engineering (HFE) activities through its Light Water Reactor Sustainability (LWRS) program to modernize the main control rooms (MCR) of commercial nuclear power plants (NPP). Idaho National Laboratory (INL), in partnership with numerous commercial nuclear utilities, has conducted some of this R&D to enable the life extension of NPPs (i.e., provide the technical basis for the long-term reliability, productivity, safety, and security of U.S. NPPs). From these activities performed to date, a human factors meta model for U.S. NPP control room modernization can now be formulated. This paper discusses this emergent HFE meta model for NPP control room modernization, with the goal of providing an integrated high level roadmap and guidance on how to perform human factors R&D and HFE for those in the U.S. nuclear industry that are engaging in the process of upgrading their MCRs.

  7. Control of metabolism by nutrient-regulated nuclear receptors acting in the brain.

    Science.gov (United States)

    Bantubungi, Kadiombo; Prawitt, Janne; Staels, Bart

    2012-07-01

    Today, we are witnessing a rising incidence of obesity worldwide. This increase is due to a sedentary life style, an increased caloric intake and a decrease in physical activity. Obesity contributes to the appearance of type 2 diabetes, dyslipidemia and cardiovascular complications due to atherosclerosis, and nephropathy. Therefore, the development of new therapeutic strategies may become a necessity. Given the metabolism controlling properties of nuclear receptors in peripheral organs (such as liver, adipose tissues, pancreas) and their implication in various processes underlying metabolic diseases, they constitute interesting therapeutic targets for obesity, dyslipidemia, cardiovascular disease and type 2 diabetes. The recent identification of the central nervous system as a player in the control of peripheral metabolism opens new avenues to our understanding of the pathophysiology of obesity and type 2 diabetes and potential novel ways to treat these diseases. While the metabolic functions of nuclear receptors in peripheral organs have been extensively investigated, little is known about their functions in the brain, in particular with respect to brain control of energy homeostasis. This review provides an overview of the relationships between nuclear receptors in the brain, mainly at the hypothalamic level, and the central regulation of energy homeostasis. In this context, we will particularly focus on the role of PPARα, PPARγ, LXR and Rev-erbα. Copyright © 2011 Elsevier Ltd. All rights reserved.

  8. Modeling and Control of Fluid Flow Networks with Application to a Nuclear-Solar Hybrid Plant

    Directory of Open Access Journals (Sweden)

    Zhe Dong

    2017-11-01

    Full Text Available Fluid flow networks (FFNs can be utilized to integrate multiple once-through heat supply system (OTHSS modules based on either the same or different energy resources such as the renewable, nuclear and fossil for multi-modular and hybrid energy systems. Modeling and control is very important for the safe, stable and efficient operation of the FFNs, whose objective is to maintain both the flowrates and pressure-drops of the network branches within specific bounds. In this paper, a differential-algebraic nonlinear dynamic model for general FFNs with multiple pump branches is proposed based on both the branch hydraulics and network graph properties. Then, an adaptive decentralized FFN flowrate-pressure control law, which takes a proportional-integral (PI form with saturation on the integral terms, is established. This newly-built control not only guarantees satisfactory closed-loop global stability but also has no need for the values of network hydraulic parameters. This adaptive control is then applied to the flowrate-pressure regulation of the secondary FFN of a two-modular nuclear-solar hybrid energy system and numerical simulation results show the feasibility and high performance of this network control strategy. Due to its concise form, this new flowrate-pressure FFN controller can be easily implemented practically.

  9. Nuclear receptor DHR4 controls the timing of steroid hormone pulses during Drosophila development.

    Directory of Open Access Journals (Sweden)

    Qiuxiang Ou

    2011-09-01

    Full Text Available In insects, precisely timed periodic pulses of the molting hormone ecdysone control major developmental transitions such as molts and metamorphosis. The synthesis and release of ecdysone, a steroid hormone, is itself controlled by PTTH (prothoracicotopic hormone. PTTH transcript levels oscillate with an 8 h rhythm, but its significance regarding the timing of ecdysone pulses is unclear. PTTH acts on its target tissue, the prothoracic gland (PG, by activating the Ras/Raf/ERK pathway through its receptor Torso, however direct targets of this pathway have yet to be identified. Here, we demonstrate that Drosophila Hormone Receptor 4 (DHR4, a nuclear receptor, is a key target of the PTTH pathway and establishes temporal boundaries by terminating ecdysone pulses. Specifically, we show that DHR4 oscillates between the nucleus and cytoplasm of PG cells, and that the protein is absent from PG nuclei at developmental times when low titer ecdysone pulses occur. This oscillatory behavior is blocked when PTTH or torso function is abolished, resulting in nuclear accumulation of DHR4, while hyperactivating the PTTH pathway results in cytoplasmic retention of the protein. Increasing DHR4 levels in the PG can delay or arrest development. In contrast, reducing DHR4 function in the PG triggers accelerated development, which is caused by precocious ecdysone signaling due to a failure to repress ecdysone pulses. Finally, we show that DHR4 negatively regulates the expression of a hitherto uncharacterized cytochrome P450 gene, Cyp6t3. Disruption of Cyp6t3 function causes low ecdysteroid titers and results in heterochronic phenotypes and molting defects, indicating a novel role in the ecdysone biosynthesis pathway. We propose a model whereby nuclear DHR4 controls the duration of ecdysone pulses by negatively regulating ecdysone biosynthesis through repression of Cyp6t3, and that this repressive function is temporarily overturned via the PTTH pathway by removing DHR4

  10. Pulsed estrogen therapy prevents post-OVX porcine dura mater microvascular network weakening via a PDGF-BB-dependent mechanism.

    Directory of Open Access Journals (Sweden)

    Olga V Glinskii

    Full Text Available In postmenopausal women, estrogen (E2 deficiencies are frequently associated with higher risk of intracranial hemorrhage, increased incidence of stroke, cerebral aneurysm, and decline in cognitive abilities. In younger postpartum women and those using oral contraceptives, perturbations in E2 are associated with higher risk of cerebral venous thrombosis. A number of serious intracranial pathologic conditions linked to E2 deficiencies, such as dural sinus thrombosis, dural fistulae, non-parenchymal intracranial hemorrhages, migraines, and spontaneous cerebrospinal fluid leaks, involve the vessels not of the brain itself, but of the outer fibrous membrane of the brain, the dura mater (DM. The pathogenesis of these disorders remains mysterious and how estrogen regulates structural and functional integrity of DM vasculature is largely unknown. Here, we demonstrate that post ovariectomy (OVX DM vascular remodeling is manifested by microvessel destabilization, capillary rarefaction, increased vascular permeability, and aberrant angio-architecture, and is the result of disrupted E2-regulated PDGF-BB signaling within dura microvasculature. These changes, associated with the reduction in systemic PDGF-BB levels, are not corrected by a flat-dose E2 hormone replacement therapy (HRT, but are largely prevented using HRT schedules mimicking physiological E2 fluctuations. We demonstrate that 1 E2 regulates PDGF-BB production by endothelial cells in a dose-dependent manner and 2 optimization of PDGF-BB levels and induction of robust PDGF-mediated endothelial cell-vascular pericyte interactions require high (estrous E2 concentrations. We conclude that high (estrous levels of E2 are important in controlling PDGF-mediated crosstalk between endothelial cells and pericytes, a fundamental mechanism governing microvessel stability and essential for preserving intracranial homeostasis.

  11. Externalización de la gestión documental audiovisual en las televisiones por medio de productoras audiovisuales y agencias de noticias

    National Research Council Canada - National Science Library

    CALDERA-SERRANO, Jorge

    2015-01-01

    ... de la organización documental, los ajustes de los recursos humanos y económicos así como la adquisición de la descripción de análisis del contenido a empresas creadoras de contenidos tales como las productoras y las agencias de noticias audiovisuales...

  12. Las Agencias de Viajes ante la influencia de las Redes Sociales en el turismo. El caso de Ourense.

    Directory of Open Access Journals (Sweden)

    Laura Rodríguez Cid

    2015-01-01

    Full Text Available El modelo turístico tradicional ha experimentado un cambio con la llegada de las nuevas tecnologías. Las tradicionales herramientas de marketing empleadas por las Agencias de Viajes se están quedando atrás para dar paso a nuevos y mejorados métodos de comercialización y promoción de productos turísticos basados en la utilización de las Tecnologías de la Información y la Comunicación (TIC. Los hábitos de compra han cambiado debido a la rápida evolución de Internet en los últimos 10 años. Se ha pasado de la Web 1.0, de carácter estático y de lectura, a la Web 2.0 que ha generalizado la creación de contenidos y la comunicación on -line entre usuarios, convirtiéndose en creadores y a su vez en consumidores de la información. En los últimos años, las empresas turísticas han comenzado a crear canales de comercialización directos con el cliente, evitando así negociar con los intermediarios, lo que ha mejorado la eficiencia y la reducción de costes. Esto ha permitido que los usuarios puedan contratar un viaje o un servicio turístico a través de la red con unos costes notablemente inferiores. El asesoramiento que antes sólo se encontraba en las Agencias de Viajes, ahora es proporcionado por los usuarios que han consumido el servicio y cuya experiencia aporta una visión única y diferente. Todo este fenómeno ha ocasionado que este sector pase a un segundo plano, con un turista más experimentado, más exigente y familiarizado con estas nuevas herramientas nacidas de la Web 2.0. Numerosas agencias han cerrado sus negocios y tienden a desaparecer tal y como las conocemos actualmente. Sin embargo, son muchas las posibilidades que se les presentan si se adaptan al mercado actual, un entorno que fomenta el uso de las nuevas tecnologías y que utiliza la Web 2.0 y las Redes Sociales para mantener y captar nuevos clientes.

  13. Development of a control logic for nuclear heating operation for primary system for SMART

    Energy Technology Data Exchange (ETDEWEB)

    Seo, Jae Kwang; Kang, H. O.; Yoon, J. H.; Kim, K. K.; Lee, D. J

    2000-11-01

    A nuclear heating concept is adopted in the SMART compared with the commercial nuclear power plant using the primary coolant pumps for heating the primary system. In this report, five options of heatup control logic are proposed and each option is evaluated using MMS code. In option 1, control rod is controlled by a signal of difference in require heatup rate (dT/dt)req. and actual heatup rate (dT/dt)act., which is calculated from the measured value of core outlet temperature. In option 2, control rod is controlled by a signal of difference in reference temperature and actual measured temperature. In option 3, control rod is controlled by a signal of difference in required core power Qcore and actual measured core power N. Primary side temperature difference in measured values between steam generator (SG) inlet and outlet is used in determining Qcore in option 3. Because of this dependency on difference in measured temperature Qcore, in conjunction with measurement channel error in temperature, involves certain uncertainty during specially low flow conditions where primary side temperature difference in SG inlet and outlet is very small. Option 4 is a modified version of option 3. In option 4, SG outlet temperature is not needed to calculate Qcore. However a compensating program which enable Qcore to be evaluated without SG outlet temperature is needed. In option 5, control rod is controlled by a signal of difference in required preset step core power Qcore and actual measured core power N. From the simulation results it is concluded that option 5 using step power setting during heatup operation is suitable for as a heatup control logic for SMART.

  14. Brasil, Argentina e América do Sul

    Directory of Open Access Journals (Sweden)

    Paulo Nogueira Batista Jr.

    2005-12-01

    Full Text Available ESTE trabalho discute alguns aspectos da evolução econômica recente do Brasil, da Argentina e de outros países da América do Sul. Tendências econômicas e intelectuais perigosas, tais como a "globalização", o chamado Consenso de Washington, a dolarização e as negociações da Alca (Área de Livre Comércio das Américas, perderam ímpeto e a América do Sul está se movendo gradualmente na direção de um posicionamento mais independente na condução das suas política econômicas e internacionais. As mudanças foram muito mais significativas na Argentina do que no Brasil e isso se tornou fonte de alguma tensão entre os dois principais países sul-americanos. Não obstante, uma aliança estratégica entre Argentina e Brasil continua sendo a pedra angular da integração da América do Sul.THIS PAPER discusses some aspects of the recent economic evolution of Brazil, Argentina and other South American countries. Dangerous economic and intellectual trends, such as "globalization", the so-called Washington Consensus, dollarization, and FTAA (Free Trade Area of the Americas negotiations, have lost momentum and South America is moving gradually towards a more independent stance in the conduct of its economic and foreign policies. Changes have been much more significant in Argentina than in Brazil and this has become a source of some tension between the two major South American countries. Nevertheless, a strategic alliance between Argentina and Brazil remains the corner stone of South American integration.

  15. Material control and accounting in the Department of Energy's nuclear fuel complex

    Energy Technology Data Exchange (ETDEWEB)

    None

    1989-01-01

    Material control and accounting takes place within an envelope of activities related to safeguards and security, as well as to safety, health, and environment, all of which need to be managed to assure that the entire nuclear fuel complex can operate in a societally accepted manner. Within this envelope the committee was directed to carry out the following scope of work: (1) Review the MCandA systems in use at selected DOE facilities that are processing special nuclear material (SNM) in various physical and chemical forms. (2) Design and convene a workshop for senior representatives from each of DOE's facilities on the flows and inventories of nuclear materials. (3) Plan and conduct a series of site visits to each of the facilities to observe first hand the processing operations and the related MCandA systems. (4) Review the potential improvement in overall safeguard systems effectiveness, as measured by expected reduction in inventory difference control limits and inventory differences for materials balance accounts and facilities, or other criteria as appropriate. Indicate how this affects the relative degree of uncertainty in the system. (5) Review the efficiency of operating the MCandA system with and without the upgrading options and assess whether upgrading will contribute further efficiencies in operation, which may reduce many of the current operations costs. Determine if the current system is cost-effective. (6) Recommend the most promising technical approaches for further development by DOE and further study as warranted.

  16. Nuclear Rocket Test Facility Decommissioning Including Controlled Explosive Demolition of a Neutron-Activated Shield Wall

    Energy Technology Data Exchange (ETDEWEB)

    Michael Kruzic

    2007-09-01

    Located in Area 25 of the Nevada Test Site, the Test Cell A Facility was used in the 1960s for the testing of nuclear rocket engines, as part of the Nuclear Rocket Development Program. The facility was decontaminated and decommissioned (D&D) in 2005 using the Streamlined Approach For Environmental Restoration (SAFER) process, under the Federal Facilities Agreement and Consent Order (FFACO). Utilities and process piping were verified void of contents, hazardous materials were removed, concrete with removable contamination decontaminated, large sections mechanically demolished, and the remaining five-foot, five-inch thick radiologically-activated reinforced concrete shield wall demolished using open-air controlled explosive demolition (CED). CED of the shield wall was closely monitored and resulted in no radiological exposure or atmospheric release.

  17. Review of Methods Related to Assessing Human Performance in Nuclear Power Plant Control Room Simulations

    Energy Technology Data Exchange (ETDEWEB)

    Katya L Le Blanc; Ronald L Boring; David I Gertman

    2001-11-01

    With the increased use of digital systems in Nuclear Power Plant (NPP) control rooms comes a need to thoroughly understand the human performance issues associated with digital systems. A common way to evaluate human performance is to test operators and crews in NPP control room simulators. However, it is often challenging to characterize human performance in meaningful ways when measuring performance in NPP control room simulations. A review of the literature in NPP simulator studies reveals a variety of ways to measure human performance in NPP control room simulations including direct observation, automated computer logging, recordings from physiological equipment, self-report techniques, protocol analysis and structured debriefs, and application of model-based evaluation. These methods and the particular measures used are summarized and evaluated.

  18. Teoría de agencia: una revisión del origen biológico del delito

    Directory of Open Access Journals (Sweden)

    Iván Araya

    2016-01-01

    Full Text Available Este trabajo aborda la causa del conflicto entre principal y agente, buscando respuestas en las disciplinasde la biología, particularmente en las ciencias de la antropología criminal. Se ha realizado un ensambleentre los hallazgos de la teoría de agencia y la teoría de los delitos de cuello blanco, reinterpretando lasactuaciones del agente desde su configuración entre instinto, herencia y personalidad. Los resultadosen las ciencias biológicas podrían aportar nuevas interpretaciones y explicaciones en las ciencias de laadministración, avanzando hacia mejores conceptualizaciones del conflicto, mediante teorías con mayorcontenido empírico. En general, pese al conflicto permanente entre las partes, su dinámica potencia losresultados perseguidos por el principal.

  19. Teoría de agencia: una revisión del origen biológico del delito

    Directory of Open Access Journals (Sweden)

    Iván Araya

    2016-04-01

    Full Text Available Este trabajo aborda la causa del conflicto entre principal y agente, buscando respuestas en las disciplinas de la biología, particularmente en las ciencias de la antropología criminal. Se ha realizado un ensamble entre los hallazgos de la teoría de agencia y la teoría de los delitos de cuello blanco, reinterpretando las actuaciones del agente desde su configuración entre instinto, herencia y personalidad. Los resultados en las ciencias biológicas podrían aportar nuevas interpretaciones y explicaciones en las ciencias de la administración, avanzando hacia mejores conceptualizaciones del conflicto, mediante teorías con mayor contenido empírico. En general, pese al conflicto permanente entre las partes, su dinámica potencia los resultados perseguidos por el principal.

  20. Model-Free Coordinated Control for MHTGR-Based Nuclear Steam Supply Systems

    Directory of Open Access Journals (Sweden)

    Zhe Dong

    2016-01-01

    Full Text Available The modular high temperature gas-cooled reactor (MHTGR is a typical small modular reactor (SMR that offers simpler, standardized and safer modular design by being factory built, requiring smaller initial capital investment, and having a shorter construction period. Thanks to its small size, the MHTGRs could be beneficial in providing electric power to remote areas that are deficient in transmission or distribution and in generating local power for large population centers. Based on the multi-modular operation scheme, the inherent safety feature of the MHTGRs can be applicable to large nuclear plants of any desired power rating. The MHTGR-based nuclear steam supplying system (NSSS is constituted by an MHTGR, a side-by-side arranged helical-coil once-through steam generator (OTSG and some connecting pipes. Due to the side-by-side arrangement, there is a tight coupling effect between the MHTGR and OTSG. Moreover, there always exists the parameter perturbation of the NSSSs. Thus, it is meaningful to study the model-free coordinated control of MHTGR-based NSSSs for safe, stable, robust and efficient operation. In this paper, a new model-free coordinated control strategy that regulates the nuclear power, MHTGR outlet helium temperature and OTSG outlet overheated steam temperature by properly adjusting the control rod position, helium flowrate and feed-water flowrate is established for the MHTGR-based NSSSs. Sufficient conditions for the globally asymptotic closed-loop stability is given. Finally, numerical simulation results in the cases of large range power decrease and increase illustrate the satisfactory performance of this newly-developed model-free coordinated NSSS control law.

  1. Argonne National Laboratory papers presented at third ANS topical meeting on the technology of controlled nuclear fusion

    Energy Technology Data Exchange (ETDEWEB)

    1978-01-01

    The 9 papers included in this Technical Memorandum were presented at the Third ANS Topical Meeting on the Technology of Controlled Nuclear Fusion that was held in Santa Fe, New Mexico on May 9-11, 1978.

  2. Advantages of a program of quality control in the nuclear medicine equipment; Ventajas de un programa de control de calidad en los equipos de medicina nuclear

    Energy Technology Data Exchange (ETDEWEB)

    Trujillo Z, F.E.; Argumosa, E. [Departamento de Medicina Nuclear del Instituto Nacional de Cancerologia, Tlalpan, Mexico D.F. (Mexico); Herrera R, M.R. [Hospital Infantil de Mexico ' Federico Gomez' , Mexico D.F. (Mexico)

    2007-07-01

    In Nuclear Medicine more 90% of the entirety of the carried out procedures its are with diagnostic ends where it is acquired one or several images. This makes indispensable to have an appropriate operation of the dedicated equipment to produce images and also of those non former images, as the activity caliper, to assure an appropriate quality diagnoses not from the images and the correct dose administration to the patient. In this work the main calibrations that should be carried out and an example of the program of quality control of a gamma camera mark Siemens and model E.CAM are presented. Considerations that should take as for the radiological protection are exposed. Comments on the parameters that correct the required calibrations and the images taken place by an operation or inadequate calibrations are included. In conclusion, the necessity of a program that it contains as minimum the quality control of the gamma cameras and of the activity caliper, having as main advantages a good image quality diagnoses and to minimize the dose imparted the patient are exposed. (Author)

  3. Results of automatic system implementation for the friction control rods execution in Cofrentes nuclear power plant

    Energy Technology Data Exchange (ETDEWEB)

    Palomo, M., E-mail: mpalomo@iqn.upv.es [Universidad Politecnica de Valencia (UPV) (Spain); Urrea, M., E-mail: matias.urrea@iberdrola.es [Iberdrola Generacion S.A. Valencia (Spain). C.N. Cofrentes; Curiel, M., E-mail: m.curiel@lainsa.com [Logistica y Acondicionamientos Industriales (LAINSA), Valencia (Spain); Arnaldos, A., E-mail: a.arnaldos@titaniast.com [TITANIA Servicios Teconologicos, Valencia (Spain)

    2011-07-01

    The purpose of this presentation is to show the obtained results in Cofrentes Nuclear Power Plant (Spain) of Control Rods PCC/24 Friction Test Procedure. In order to perform this, a Control Rod Friction Test System has been developed. Principally, this system consists on software and data acquisition hardware that obtains and analyzes the control rod pressure variation on which the test is being made. The PCC/24 Procedure objective is to detect an excessive friction in the control rod movement that could cause a CRD (Control Rod Drive) movement slower than usual. This test is necessary every time that an anomalous alteration is produced in the reactor core that could affect to a fuel rod, and it is executed before the time measure of control rods rapid scram test of the affected rods. This test has to be carried out to all the reactor control rods and takes valuable time during plant refuelling. So, by means of an automatic system to perform the test, we obtain an important time saving during refuelling. On the other hand, the on-line monitoring of the control rod insertion and changes in differential pressure, permits a control rod operation fast and safe validation. Moreover, an automatic individual report of every rod is generated by the system and a final global result report of the entire test developed in refuelling is generated. The mentioned reports can be attached directly to the procedure documents obtaining an office data processing important saving time.(author)

  4. Results of automatic system implementation for the friction control rods execution in Cofrentes nuclear power plant

    Energy Technology Data Exchange (ETDEWEB)

    Curiel, M. [Logistica y Acondicionamientos Industriales SAU, Sorolla Center, local 10, Av. de las Cortes Valencianas, 46015 Valencia (Spain); Palomo, M. J. [ISIRYM, Universidad Politecnica de Valencia, Camino de Vera s/n, Valencia (Spain); Urrea, M. [Iberdrola Generacion S. A., Central Nuclear Cofrentes, Carretera Almansa Requena s/n, 04662 Cofrentes, Valencia (Spain); Arnaldos, A., E-mail: m.curiel@lainsa.co [TITANIA Servicios Tecnologicos SL, Sorolla Center, local 10, Av. de las Cortes Valencianas No. 58, 46015 Valencia (Spain)

    2010-10-15

    The purpose of this presentation is to show the obtained results in Cofrentes nuclear power plant (Spain) of control rods Pcc/24 friction test procedure. In order to perform this, a control rod friction test system has been developed. Principally, this system consists on software and data acquisition hardware that obtains and analyzes the control rod pressure variation on which the test is being made. The Pcc/24 procedure objective is to detect an excessive friction in the control rod movement that could cause a control rod drive movement slower than usual. This test is necessary every time that an anomalous alteration is produced in the reactor core that could affect to a fuel rod, and it is executed before the time measure of control rods rapid scram test of the affected rods. This test has to be carried out to all the reactor control rods and takes valuable time during plant refuelling. So, by means of an automatic system to perform the test, we obtain an important time saving during refuelling. On the other hand, the on-line monitoring of the control rod insertion and changes in differential pressure, permits a control rod operation fast and safe validation. Moreover, an automatic individual report of every rod is generated by the system and a final global result report of the entire test developed in refuelling is generated. The mentioned reports can be attached directly to the procedure documents obtaining an office data processing important saving time. (Author)

  5. Studies and research concerning BNFP: computerized nuclear materials control and accounting system development evaluation report, FY 1978

    Energy Technology Data Exchange (ETDEWEB)

    Crawford, J M; Ehinger, M H; Joseph, C; Madeen, M L

    1978-10-01

    Development work on a computerized system for nuclear materials control and accounting in a nuclear fuel reprocessing plant is described and evaluated. Hardware and software were installed and tested to demonstrate key measurement, measurement control, and accounting requirements at accountability input/output points using natural uranium. The demonstration included a remote data acquisition system which interfaces process and special instrumentation to a cenral processing unit.

  6. Emociones, agencia y experiencia escolar: el papel de los vínculos en los procesos de inclusión escolar en el nivel secundario

    Directory of Open Access Journals (Sweden)

    Mariana Nobile

    2014-04-01

    Full Text Available Normal 0 false false false ES-TRAD JA X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:12.0pt; font-family:Cambria; mso-ascii-font-family:Cambria; mso-ascii-theme-font:minor-latin; mso-hansi-font-family:Cambria; mso-hansi-theme-font:minor-latin;} Desde hace unos años venimos explorando el modo en que la dimensión emocional de la experiencia escolar interviene en los procesos de inclusión-exclusión educativa en el nivel secundario. Aquí analizamos las entrevistas en profundidad realizadas a 16 jóvenes de sectores populares que han egresado de las llamadas “Escuelas de Reingreso” en las que se indagaron las formas en que enunciaban su experiencia emocional, explorando las fuentes de dicha emocionalidad. Respeto, entusiasmo y tranquilidad fueron las formas enunciativas utilizadas para describir sus experiencias. Nuestra hipótesis es que el tipo de vínculos construidos con los docentes en el marco de un formato escolar particular genera una emocionalidad positiva, que permite resignificar la trayectoria escolar personal, reposicionarse frente a la institución escolar y potenciar su sensación de agencia, en términos de sentirse con mayores márgenes de control acerca de su propia vida, permitiéndole de este modo desplegar diferentes tipos de estrategias personales para su integración laboral, educativa y familiar.

  7. The control of operational risk in nuclear power plant operations - Some cross-cultural perspectives

    Energy Technology Data Exchange (ETDEWEB)

    Suchard, A.; Rochlin, G. (Univ. of California, Berkeley (United States))

    1992-01-01

    The operation of nuclear power plants requires the management of a complex technology under exacting performance and safety criteria. Organizations operating nuclear power plants are faced with the challenge of simultaneously meeting technical, organizational, and social demands, striving toward perfection in a situation where learning by trial and error can be too costly. In this process, they interact with regulatory bodies who seek to help minimize operational risk by imposing and upholding safety standards. The character of this interaction differs in various countries, as does the larger cultural setting. The study generally pursued the question of how organizations operating complex and demanding technologies adapt to such requirements and circumstances, and how they can succeed in delivering nearly error-free performance. One aspect of this study includes the comparison of organizational and cultural environments for nuclear power plant operations in the US, France, Germany, Sweden, and Switzerland. The research involved in-depth, continuous observations on location and interviews with plant personnel, especially control operators, at one plant in each country.

  8. Operation and Control Simulation of a Modular High Temperature Gas Cooled Reactor Nuclear Power Plant

    Science.gov (United States)

    Li, Haipeng; Huang, Xiaojin; Zhang, Liangju

    2008-08-01

    Issues in the operation and control of the multi-modular nuclear power plant are complicated. The high temperature gas cooled reactor pebble-bed module (HTR-PM) plant with two-module will be built as a demonstration plant in China. To investigate the operation and control characteristics of the plant, a simplified dynamic model is developed and mathematically formulated based upon the fundamental conversation of mass, energy and momentum. The model is implemented in a personal computer to simulate the power increase process of the HTR-PM operation. The open loop operation with no controller is first simulated and the results show that the essential parameter steam temperature varies drastically with time, which is not allowable in the normal operation. According to the preliminary control strategy of the HTR-PM, a simple steam temperature controller is proposed. The controller is of Proportional-type with a time lag. The closed loop operation with a steam temperature controller is then implemented and the simulation results show that the steam temperature and also other parameters are all well controlled in the allowable range.

  9. EARLY-STAGE DESIGN AND EVALUATION FOR NUCLEAR POWER PLANT CONTROL ROOM UPGRADES

    Energy Technology Data Exchange (ETDEWEB)

    Ronald L. Boring; Jeffrey C. Joe; Thomas A. Ulrich; Roger T. Lew

    2015-03-01

    As control rooms are modernized with new digital systems at nuclear power plants, it is necessary to evaluate operator performance with these systems as part of a verification and validation process. While there is regulatory and industry guidance for some modernization activities, there are no well defined standard processes or predefined metrics available for assessing what is satisfactory operator interaction with new systems, especially during the early design stages. This paper proposes a framework defining the design process and metrics for evaluating human system interfaces as part of control room modernization. The process and metrics are generalizable to other applications and serve as a guiding template for utilities undertaking their own control room modernization activities.

  10. Quality control of inner nuclear membrane proteins by the Asi complex.

    Science.gov (United States)

    Foresti, Ombretta; Rodriguez-Vaello, Victoria; Funaya, Charlotta; Carvalho, Pedro

    2014-11-07

    Misfolded proteins in the endoplasmic reticulum (ER) are eliminated by a quality control system called ER-associated protein degradation (ERAD). However, it is unknown how misfolded proteins in the inner nuclear membrane (INM), a specialized ER subdomain, are degraded. We used a quantitative proteomics approach to reveal an ERAD branch required for INM protein quality control in yeast. This branch involved the integral membrane proteins Asi1, Asi2, and Asi3, which assembled into an Asi complex. Besides INM misfolded proteins, the Asi complex promoted the degradation of functional regulators of sterol biosynthesis. Asi-mediated ERAD was required for ER homeostasis, which suggests that spatial segregation of protein quality control systems contributes to ER function. Copyright © 2014, American Association for the Advancement of Science.

  11. Effect of Environmental Chemical Stress on Nuclear Noncoding RNA Involved in Epigenetic Control

    Directory of Open Access Journals (Sweden)

    Patrizio Arrigo

    2015-01-01

    Full Text Available In the last decade the role of noncoding RNAs (ncRNAs emerges not only as key elements of posttranscriptional gene silencing, but also as important players of epigenetic regulation. New kind and new functions of ncRNAs are continuously discovered and one of their most important roles is the mediation of environmental signals, both physical and chemical. The activity of cytoplasmic short ncRNA is extensively studied, in spite of the fact that their function and role in the nuclear compartment are not yet completely unraveled. Cellular nucleus contains a multiplicity of long and short ncRNAs controlling at different levels transcriptional and epigenetic processes. In addition, some ncRNAs are involved in RNA editing and quality control. In this paper we review the existing knowledge dealing with how chemical stressors can influence the functionality of short nuclear ncRNAs. Furthermore, we perform bioinformatics analyses indicating that chemical environmental stressors not only induce DNA damage but also influence the mechanism of ncRNAs production and control.

  12. Upgrade of the Nuclear Material Protection, Control and Accounting System at the VNIIEF Industrial Zone

    Energy Technology Data Exchange (ETDEWEB)

    Lewis, J.C.; Maltsev, V.; Singh, S.P.

    1999-09-20

    The Industrial Zone at the Russian Federal Nuclear Center/All-Russian Scientific Research Institute of Experimental Physics (RFNC/VNEEF) consists of ten guarded areas with twenty two material balance areas (A and As). The type of facilities in the Industrial Zone include storage sites, machine shops, research facilities, and training facilities. Modernization of the Material Protection, Control and Accounting (MPC and A) System at the Industrial Zone started in 1997. This paper provides a description of, the methodology/strategy used in the upgrade of the MFC and A system.

  13. Modal seismic analysis of a nuclear power plant control panel and comparison with SAP 4

    Science.gov (United States)

    Pamidi, M. R.; Pamidi, P. R.

    1976-01-01

    The application of NASTRAN to seismic analysis by considering the example of a nuclear power plant control panel was considered. A modal analysis of a three-dimensional model of the panel, consisting of beam and quadri-lateral membrane elements, is performed. Using the results of this analysis and a typical response spectrum of an earthquake, the seismic response of the structure is obtained. ALTERs required to the program in order to compute the maximum modal responses as well as the resultant response are given. The results are compared with those obtained by using the SAP IV computer program.

  14. State-of-the-art report for the instrumentation and control technology based on the nuclear-information technology convergence

    Energy Technology Data Exchange (ETDEWEB)

    Kwon, Kee Choon; Kim, Chang Hwoi; Lee, Dong Young; Lee, Cheol Kwon; Lee, Hyun Chul [KAERI, Daejeon (Korea, Republic of)

    2011-12-15

    As digitalized the instrumentation and control systems in nuclear power plants, in the past that were implemented in an analog system or circuit for monitoring, control and protection, most of the them is implemented in embedded software based on hardware platform. Digital instrumentation and control system hardware platforms and a digital safety systems have developed in Korea. The fundamental technology of the software part of MMIS (Man-Machine Interface System) has achieved the localization. But in order to secure our global competitiveness, in the -based software, the source of the content areas / It is needed to develop core technologies of the software and contents areas based on the nuclear-IT convergence technology. In this report, the IT technology centered for the characteristics of embedded software applied to nuclear power is described. Also state-of-the-art IT technologies that will converge to nuclear power plants are mentioned

  15. JRTF: A Flexible Software Framework for Real-Time Control in Magnetic Confinement Nuclear Fusion Experiments

    Science.gov (United States)

    Zhang, M.; Zheng, G. Z.; Zheng, W.; Chen, Z.; Yuan, T.; Yang, C.

    2016-04-01

    The magnetic confinement nuclear fusion experiments require various real-time control applications like plasma control. ITER has designed the Fast Plant System Controller (FPSC) for this job. ITER provided hardware and software standards and guidelines for building a FPSC. In order to develop various real-time FPSC applications efficiently, a flexible real-time software framework called J-TEXT real-time framework (JRTF) is developed by J-TEXT tokamak team. JRTF allowed developers to implement different functions as independent and reusable modules called Application Blocks (AB). The AB developers only need to focus on implementing the control tasks or the algorithms. The timing, scheduling, data sharing and eventing are handled by the JRTF pipelines. JRTF provides great flexibility on developing ABs. Unit test against ABs can be developed easily and ABs can even be used in non-JRTF applications. JRTF also provides interfaces allowing JRTF applications to be configured and monitored at runtime. JRTF is compatible with ITER standard FPSC hardware and ITER (Control, Data Access and Communication) CODAC Core software. It can be configured and monitored using (Experimental Physics and Industrial Control System) EPICS. Moreover the JRTF can be ported to different platforms and be integrated with supervisory control software other than EPICS. The paper presents the design and implementation of JRTF as well as brief test results.

  16. Quality assessment of radiopharmaceuticals in nuclear medicine services at Northeast states, Brazil; Avaliacao da qualidade de radiofarmacos em servicos de medicina nuclear de estados da regiao nordeste

    Energy Technology Data Exchange (ETDEWEB)

    Andrade, Wellington Gomes de

    2012-07-01

    The radiopharmaceuticals are used in the field nuclear medicine services (NMS) as tracer in the diagnoses and treatment of many diseases. Radiopharmaceuticals used in nuclear medicine and usually have a minimum of pharmacological effect. The procedures for labelling Radiopharmaceuticals should be observed in order to minimize risks to patients, employees and individuals from the public, and to be administered in humans, must be sterile and free of pyrogens and possess elements all measures of quality controls required a conventional drug. The 'Agencia Nacional de Vigilancia Sanitaria (ANVISA)' in its 'Resolucao de Diretoria Colegiada' (RDC) No. 38 of June 4{sup th} 2008, decided that the NMS must perform quality control in the generators eluate and radiopharmaceuticals according to recommendations of manufacturers and scientific evidence accepted by ANVISA. Thus, this study proposes to evaluate the quality of the generator {sup 99M}o-{sup 99m}Tc eluate and radiopharmaceuticals labeled with {sup 99m}Tc used in most NMS of some states in the Northeast, in relation to radionuclide, chemical, radiochemical purity and pH and promote the inclusion of procedure for quality control of radiopharmaceuticals in routine NMS. The results show that 90% radionuclidic purity, 98.2% purity chemical and radiochemical purity of 46% and 100% of the eluates are in agreement with international pharmacopoeias; already radiopharmaceuticals showed 82.6% purity and all radiochemical pH values are also in accordance with international pharmacopoeias. Even with so many positive results, staff the majority of MNS was not able to perform the quality control of the eluates and radiopharmaceuticals. Showing the importance of implementing of quality control programs of the eluates and radiopharmaceuticals in nuclear medicine. (author)

  17. Nutrient-sensing nuclear receptors PPARα and FXR control liver energy balance.

    Science.gov (United States)

    Preidis, Geoffrey A; Kim, Kang Ho; Moore, David D

    2017-04-03

    The nuclear receptors PPARα (encoded by NR1C1) and farnesoid X receptor (FXR, encoded by NR1H4) are activated in the liver in the fasted and fed state, respectively. PPARα activation induces fatty acid oxidation, while FXR controls bile acid homeostasis, but both nuclear receptors also regulate numerous other metabolic pathways relevant to liver energy balance. Here we review evidence that they function coordinately to control key nutrient pathways, including fatty acid oxidation and gluconeogenesis in the fasted state and lipogenesis and glycolysis in the fed state. We have also recently reported that these receptors have mutually antagonistic impacts on autophagy, which is induced by PPARα but suppressed by FXR. Secretion of multiple blood proteins is a major drain on liver energy and nutrient resources, and we present preliminary evidence that the liver secretome may be directly suppressed by PPARα, but induced by FXR. Finally, previous studies demonstrated a striking deficiency in bile acid levels in malnourished mice that is consistent with results in malnourished children. We present evidence that hepatic targets of PPARα and FXR are dysregulated in chronic undernutrition. We conclude that PPARα and FXR function coordinately to integrate liver energy balance.

  18. Nuclear hormone receptor NHR-49 controls fat consumption and fatty acid composition in C. elegans.

    Directory of Open Access Journals (Sweden)

    Marc R Van Gilst

    2005-02-01

    Full Text Available Mammalian nuclear hormone receptors (NHRs, such as liver X receptor, farnesoid X receptor, and peroxisome proliferator-activated receptors (PPARs, precisely control energy metabolism. Consequently, these receptors are important targets for the treatment of metabolic diseases, including diabetes and obesity. A thorough understanding of NHR fat regulatory networks has been limited, however, by a lack of genetically tractable experimental systems. Here we show that deletion of the Caenorhabditis elegans NHR gene nhr-49 yielded worms with elevated fat content and shortened life span. Employing a quantitative RT-PCR screen, we found that nhr-49 influenced the expression of 13 genes involved in energy metabolism. Indeed, nhr-49 served as a key regulator of fat usage, modulating pathways that control the consumption of fat and maintain a normal balance of fatty acid saturation. We found that the two phenotypes of the nhr-49 knockout were linked to distinct pathways and were separable: The high-fat phenotype was due to reduced expression of enzymes in fatty acid beta-oxidation, and the shortened adult life span resulted from impaired expression of a stearoyl-CoA desaturase. Despite its sequence relationship with the mammalian hepatocyte nuclear factor 4 receptor, the biological activities of nhr-49 were most similar to those of the mammalian PPARs, implying an evolutionarily conserved role for NHRs in modulating fat consumption and composition. Our findings in C. elegans provide novel insights into how NHR regulatory networks are coordinated to govern fat metabolism.

  19. Advanced Outage and Control Center: Strategies for Nuclear Plant Outage Work Status Capabilities

    Energy Technology Data Exchange (ETDEWEB)

    Gregory Weatherby

    2012-05-01

    The research effort is a part of the Light Water Reactor Sustainability (LWRS) Program. LWRS is a research and development program sponsored by the Department of Energy, performed in close collaboration with industry to provide the technical foundations for licensing and managing the long-term, safe and economical operation of current nuclear power plants. The LWRS Program serves to help the US nuclear industry adopt new technologies and engineering solutions that facilitate the continued safe operation of the plants and extension of the current operating licenses. The Outage Control Center (OCC) Pilot Project was directed at carrying out the applied research for development and pilot of technology designed to enhance safe outage and maintenance operations, improve human performance and reliability, increase overall operational efficiency, and improve plant status control. Plant outage management is a high priority concern for the nuclear industry from cost and safety perspectives. Unfortunately, many of the underlying technologies supporting outage control are the same as those used in the 1980’s. They depend heavily upon large teams of staff, multiple work and coordination locations, and manual administrative actions that require large amounts of paper. Previous work in human reliability analysis suggests that many repetitive tasks, including paper work tasks, may have a failure rate of 1.0E-3 or higher (Gertman, 1996). With between 10,000 and 45,000 subtasks being performed during an outage (Gomes, 1996), the opportunity for human error of some consequence is a realistic concern. Although a number of factors exist that can make these errors recoverable, reducing and effectively coordinating the sheer number of tasks to be performed, particularly those that are error prone, has the potential to enhance outage efficiency and safety. Additionally, outage management requires precise coordination of work groups that do not always share similar objectives. Outage

  20. Modeling and control of a nuclear power plant using AI techniques

    Energy Technology Data Exchange (ETDEWEB)

    Oliveira, Mauro Vitor de; Almeida, Jose Carlos Soares de, E-mail: mvitor@ien.gov.br, E-mail: jcsa@ien.gov.br [Instituto de Engenharia Nuclear (IEN/CNEN-RJ), Rio de Janeiro, RJ (Brazil)

    2013-07-01

    In pressurized water reactor (PWR) nuclear power plants (NPPs) pressure control in the primary loops is fundamental for keeping the reactor in a safety condition and improve the generation process efficiency. The main component responsible for this task is the pressurizer. The pressurizer pressure control system (PPCS) utilizes heaters and spray valves to maintain the pressure within an operating band during steady state conditions, and limits the pressure changes during transient conditions. Relief and safety valves provide overpressure protection for the reactor coolant system (RCS) to ensure system integrity. Various protective reactor trips are generated if the system parameters exceed safe bounds. Historically, a proportional-integral-derivative (PID) controller is used in PWRs to keep the pressure in the set point, during those operation conditions. The purpose of this study is to develop fuzzy controllers for the PWR pressurizer modeled by an artificial neural network (ANN) and compare their performance with conventional ones. Data from a 2785 MWth Westinghouse 3-loop PWR simulator was used to test both the conventional and the fuzzy controllers. The simulation results show that the fuzzy controllers have better performance compared with conventional ones. (author)

  1. Digital control systems in nuclear power plants: Failure information, modeling concepts, and applications

    Energy Technology Data Exchange (ETDEWEB)

    Galyean, W.J.

    1993-06-23

    This report briefly describes some current applications of advanced computerized digital display and control systems at US commercial nuclear power plants and presents the results of a literature search that was made to gather information on the reliability of these systems. Both hardware and software reliability were addressed in this review. Only limited failure rate information was found, with the chemical process industry being the primary source of information on hardware failure rates and expert opinion the primary source for software failure rates. Safety-grade digital control systems are typically installed on a functional like-for-like basis, replacing older analog systems without substantially changing interactions with other plant systems. Future work includes performing a limited probabilistic risk assessment of a representative DCS to assess its risk significance.

  2. Digital control systems in nuclear power plants: Failure information, modeling concepts, and applications. Revision 1

    Energy Technology Data Exchange (ETDEWEB)

    Galyean, W.J.

    1993-06-23

    This report briefly describes some current applications of advanced computerized digital display and control systems at US commercial nuclear power plants and presents the results of a literature search that was made to gather information on the reliability of these systems. Both hardware and software reliability were addressed in this review. Only limited failure rate information was found, with the chemical process industry being the primary source of information on hardware failure rates and expert opinion the primary source for software failure rates. Safety-grade digital control systems are typically installed on a functional like-for-like basis, replacing older analog systems without substantially changing interactions with other plant systems. Future work includes performing a limited probabilistic risk assessment of a representative DCS to assess its risk significance.

  3. An integrated software testing framework for FGA-based controllers in nuclear power plants

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Jae Yeob; Kim, Eun Sub; Yoo, Jun Beom [Div. of Computer Science and Engineering, Konkuk University, Seoul (Korea, Republic of); Lee, Young Jun; Choi, Jong Gyun [MMIS Lab., Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2016-04-15

    Field-programmable gate arrays (FPGAs) have received much attention from the nuclear industry as an alternative platform to programmable logic controllers for digital instrumentation and control. The software aspect of FPGA development consists of several steps of synthesis and refinement, and also requires verification activities, such as simulations that are performed individually at each step. This study proposed an integrated software-testing framework for simulating all artifacts of the FPGA software development simultaneously and evaluating whether all artifacts work correctly using common oracle programs. This method also generates a massive number of meaningful simulation scenarios that reflect reactor shutdown logics. The experiment, which was performed on two FPGA software implementations, showed that it can dramatically save both time and costs.

  4. Engineering light-inducible nuclear localization signals for precise spatiotemporal control of protein dynamics in living cells.

    Science.gov (United States)

    Niopek, Dominik; Benzinger, Dirk; Roensch, Julia; Draebing, Thomas; Wehler, Pierre; Eils, Roland; Di Ventura, Barbara

    2014-07-14

    The function of many eukaryotic proteins is regulated by highly dynamic changes in their nucleocytoplasmic distribution. The ability to precisely and reversibly control nuclear translocation would, therefore, allow dissecting and engineering cellular networks. Here we develop a genetically encoded, light-inducible nuclear localization signal (LINuS) based on the LOV2 domain of Avena sativa phototropin 1. LINuS is a small, versatile tag, customizable for different proteins and cell types. LINuS-mediated nuclear import is fast and reversible, and can be tuned at different levels, for instance, by introducing mutations that alter AsLOV2 domain photo-caging properties or by selecting nuclear localization signals (NLSs) of various strengths. We demonstrate the utility of LINuS in mammalian cells by controlling gene expression and entry into mitosis with blue light.

  5. Vacuum-assisted closure for complex cranial wounds involving the loss of dura mater.

    Science.gov (United States)

    Powers, Alexander K; Neal, Matthew T; Argenta, Louis C; Wilson, John A; DeFranzo, Anthony J; Tatter, Stephen B

    2013-02-01

    The aim in this study was to describe the safety and efficacy of vacuum-assisted closure (VAC) in patients with complex cranial wounds with extensive scalp, bone, and dural defects who were not candidates for immediate free tissue transfer. Five patients (4 men and 1 woman) ages 24-73 years with complex cranial wounds were treated with VAC at Wake Forest Baptist Medical Center. Etiologies included trauma, squamous cell carcinoma, and malignant meningioma. Cutaneous wound defects measured as large as 15 cm in diameter. Four of the 5 patients had open skull defects with concomitant dural defects, and 1 patient had dural dehiscence. After surgical debridement, all 5 patients were treated with the direct application of a VAC device to a reapproximated dura mater (1 patient), to a pericranial flap (1 patient), or to a regenerative tissue matrix overlying CNS tissue (3 patients). In all cases involving open cranial wounds, the VAC device promoted granulation tissue formation over the dural substitute, prevented CSF leakage, and kept the wounds free from local infection. The duration of VAC therapy ranged from 16 to 91 days. Although VAC therapy was intended as a temporary measure until these patients could be stabilized for larger tissue transfer procedures or they succumbed to their primary pathology, 1 patient had a successful skin graft following VAC therapy. Hydrocephalus requiring shunt placement developed in 2 patients during VAC therapy. The VAC dressings applied to a tissue matrix or other barrier over brain tissue in extensive cranial wounds are safe and well tolerated, providing a functional barrier and preventing infection.

  6. [Ion-beam irradiated ePTFE for an artificial dura mater].

    Science.gov (United States)

    Takahashi, Noriyoshi; Ujiie, Hiroshi; Suzuki, Yoshiaki; Iwaki, Masaya; Hori, Tomokatsu

    2003-10-01

    Expanded polytetrafluoroethylene (ePTFE) is a stable polymer and widely used as a prosthesis because of its chemical inertness. However, ePTFE as an artificial dura mater is often associated with postoperative leakage of the cerebrospinal fluid (CSF) due to its very low adhesiveness to fibrin glue and surrounding tissue. The surfaces of ePTFE were modified by ion-beam irradiation in order to improve tissue adhesiveness. The morphological changes of ePTFE that was irradiated with 150 keV-He+, Net, Ar+ and Kr+ ions applied at a rate of 1 x 10(14), 5 x 10(14) and 1 x 10(15) ions/cm2 were examined with scanning electron microscopy. Next, surrounding tissue reactions to the implanted ePTFE into the rabbit calvarial defects were analyzed at intervals from 1 week up to 1 month. The micromesh structures of the ePTFE were destroyed by ion-beam irradiation, and the depth and width of the gaps increased with heavy particle ion and irradiated fluence. In an implantation study using experimental rabbits, a dura defect was patched with four types of ion-beam irradiated ePTFE with different in irradiation fluence. A CSF leakage was observed in the rabbit covered with non-irradiated ePTFE, but, CSF leakage did not occur in any of the rabbits covered with ion-beam irradiated ePTFE that adhered in a water-tight manner to surrounding tissues. Histological study indicated that fibroblast-like cells had infiltrated and anchored the gaps in the ion-beam irradiated ePTFE. Ar+ or Kr+ with 1 x 10(15) ions/cm2 irradiated ePTFE had the highest adhesiveness and produced the best healing of dura defects.

  7. Nuclear Rocket Facility Decommissioning Project: Controlled Explosive Demolition of Neutron Activated Shield Wall

    Energy Technology Data Exchange (ETDEWEB)

    Michael R. Kruzic

    2007-09-16

    Located in Area 25 of the Nevada Test Site (NTS), the Test Cell A (TCA) Facility was used in the early to mid-1960s for the testing of nuclear rocket engines, as part of the Nuclear Rocket Development Program, to further space travel. Nuclear rocket testing resulted in the activation of materials around the reactors and the release of fission products and fuel particles in the immediate area. Identified as Corrective Action Unit 115, the TCA facility was decontaminated and decommissioned (D&D) from December 2004 to July 2005 using the Streamlined Approach for Environmental Restoration (SAFER) process, under the ''Federal Facility Agreement and Consent Order''. The SAFER process allows environmental remediation and facility closure activities (i.e., decommissioning) to occur simultaneously provided technical decisions are made by an experienced decision maker within the site conceptual site model, identified in the Data Quality Objective process. Facility closure involved a seven-step decommissioning strategy. Key lessons learned from the project included: (1) Targeted preliminary investigation activities provided a more solid technical approach, reduced surprises and scope creep, and made the working environment safer for the D&D worker. (2) Early identification of risks and uncertainties provided opportunities for risk management and mitigation planning to address challenges and unanticipated conditions. (3) Team reviews provided an excellent mechanism to consider all aspects of the task, integrated safety into activity performance, increase team unity and ''buy-in'' and promoted innovative and time saving ideas. (4) Development of CED protocols ensured safety and control. (5) The same proven D&D strategy is now being employed on the larger ''sister'' facility, Test Cell C.

  8. Bile acids regulate nuclear receptor (Nur77) expression and intracellular location to control proliferation and apoptosis.

    Science.gov (United States)

    Hu, Ying; Chau, Thinh; Liu, Hui-Xin; Liao, Degui; Keane, Ryan; Nie, Yuqiang; Yang, Hui; Wan, Yu-Jui Yvonne

    2015-02-01

    Bile acids (BA) are endogenous agents capable of causing cancer throughout the gastrointestinal (GI) tract. To uncover the mechanism by which BAs exert carcinogenic effects, both human liver and colon cancer cells as well as mouse primary hepatocytes were treated with BAs and assayed for viability, genotoxic stress, and transcriptional response. BAs induced both Nur77 (NR4A1) and proinflammatory gene expression. The intracellular location of BA-induced Nur77 was time dependent; short-term (1-3 hours) exposure induced nuclear Nur77, whereas longer (1-2 days) exposure also increased cytosolic Nur77 expression and apoptosis. Inhibiting Nur77 nuclear export with leptomycin B decreased lithocholic acid (LCA)-induced apoptosis. Extended (7 days) treatment with BA generated resistance to BA with increased nuclear Nur77, viability, and mobility. While, knockdown of Nur77 in BA-resistant cells increased cellular susceptibility to LCA-induced apoptosis. Moreover, in vivo mouse xenograft experiments demonstrated that BA-resistant cells form larger tumors with elevated Nur77 expression compared with parental controls. DNA-binding and gene expression assays identified multiple survival genes (CDK4, CCND2, MAP4K5, STAT5A, and RBBP8) and a proapoptosis gene (BID) as Nur77 targets. Consistently, BA-induced upregulation of the aforementioned genes was abrogated by a lack of Nur77. Importantly, Nur77 was overexpressed in high percentage of human colon and liver cancer specimens, and the intracellular location of Nur77 correlated with elevated serum total BA levels in patients with colon cancer. These data show for the first time that BAs via Nur77 have a dual role in modulating cell survival and death. These findings establish a direct link between Nur77 and the carcinogenic effect of BAs. ©2014 American Association for Cancer Research.

  9. Digital Full-Scope Simulation of a Conventional Nuclear Power Plant Control Room, Phase 2: Installation of a Reconfigurable Simulator to Support Nuclear Plant Sustainability

    Energy Technology Data Exchange (ETDEWEB)

    Ronald L. Boring; Vivek Agarwal; Kirk Fitzgerald; Jacques Hugo; Bruce Hallbert

    2013-03-01

    The U.S. Department of Energy’s Light Water Reactor Sustainability program has developed a control room simulator in support of control room modernization at nuclear power plants in the U.S. This report highlights the recent completion of this reconfigurable, full-scale, full-scope control room simulator buildout at the Idaho National Laboratory. The simulator is fully reconfigurable, meaning it supports multiple plant models developed by different simulator vendors. The simulator is full-scale, using glasstop virtual panels to display the analog control boards found at current plants. The present installation features 15 glasstop panels, uniquely achieving a complete control room representation. The simulator is also full-scope, meaning it uses the same plant models used for training simulators at actual plants. Unlike in the plant training simulators, the deployment on glasstop panels allows a high degree of customization of the panels, allowing the simulator to be used for research on the design of new digital control systems for control room modernization. This report includes separate sections discussing the glasstop panels, their layout to mimic control rooms at actual plants, technical details on creating a multi-plant and multi-vendor reconfigurable simulator, and current efforts to support control room modernization at U.S. utilities. The glasstop simulator provides an ideal testbed for prototyping and validating new control room concepts. Equally importantly, it is helping create a standardized and vetted human factors engineering process that can be used across the nuclear industry to ensure control room upgrades maintain and even improve current reliability and safety.

  10. Development of a nuclear reactor control system simulator using virtual instruments

    Energy Technology Data Exchange (ETDEWEB)

    Pinto, Antonio Juscelino; Mesquita, Amir Zacarias; Lameiras, Fernando Soares, E-mail: ajp@cdtn.b, E-mail: amir@cdtn.b, E-mail: fsl@cdtn.b [Centro de Desenvolvimento da Tecnologia Nuclear (CDTN/CNEN-MG), Belo Horizonte, MG (Brazil)

    2011-07-01

    The International Atomic Energy Agency recommends the use of safety and friendly interfaces for monitoring and controlling the operational parameters of the nuclear reactors. This article describes a digital system being developed to simulate the behavior of the operating parameters using virtual instruments. The control objective is to bring the reactor power from its source level (mW) to a full power (kW). It is intended for education of basic reactor neutronic and thermohydraulic principles such as the multiplication factor, criticality, reactivity, period, delayed neutron, control by rods, fuel and coolant temperatures, power, etc. The 250 kW IPR-R1 TRIGA research reactor at Nuclear Technology Development Centre - CDTN was used as reference. TRIGA reactors, developed by General Atomics (GA), are the most widely used research reactor in the world. The simulator system is being developed using the LabVIEW (Laboratory Virtual Instruments Engineering Workbench) software, considering the modern concept of virtual instruments (VI's) using electronic processor and visual interface in video monitor. The main purpose of the system is to provide training tools for instructors and students, allowing navigating by user-friendly operator interface and monitoring tendencies of the operational variables. It will be an interactive tool for training and teaching and could be used to predict the reactor behavior. Some scenarios are presented to demonstrate that it is possible to know the behavior of some variables from knowledge of input parameters. The TRIGA simulator system will allow the study of parameters, which affect the reactor operation, without the necessity of using the facility. (author)

  11. Medical Image Processing Server applied to Quality Control of Nuclear Medicine.

    Science.gov (United States)

    Vergara, C.; Graffigna, J. P.; Marino, E.; Omati, S.; Holleywell, P.

    2016-04-01

    This paper is framed within the area of medical image processing and aims to present the process of installation, configuration and implementation of a processing server of medical images (MIPS) in the Fundación Escuela de Medicina Nuclear located in Mendoza, Argentina (FUESMEN). It has been developed in the Gabinete de Tecnologia Médica (GA.TE.ME), Facultad de Ingeniería-Universidad Nacional de San Juan. MIPS is a software that using the DICOM standard, can receive medical imaging studies of different modalities or viewing stations, then it executes algorithms and finally returns the results to other devices. To achieve the objectives previously mentioned, preliminary tests were conducted in the laboratory. More over, tools were remotely installed in clinical enviroment. The appropiate protocols for setting up and using them in different services were established once defined those suitable algorithms. Finally, it’s important to focus on the implementation and training that is provided in FUESMEN, using nuclear medicine quality control processes. Results on implementation are exposed in this work.

  12. Verification of failover effects from distributed control system communication networks in digitalized nuclear power plants

    Energy Technology Data Exchange (ETDEWEB)

    Min, Moon Gi; Lee, Jae Ki; Lee, Kwang Hyun; Lee, Dong Il; Lim, Hee Taek [Korea Hydro and Nuclear Power Co., Ltd, Daejeon (Korea, Republic of)

    2017-08-15

    Distributed Control System (DCS) communication networks, which use Fast Ethernet with redundant networks for the transmission of information, have been installed in digitalized nuclear power plants. Normally, failover tests are performed to verify the reliability of redundant networks during design and manufacturing phases; however, systematic integrity tests of DCS networks cannot be fully performed during these phases because all relevant equipment is not installed completely during these two phases. In additions, practical verification tests are insufficient, and there is a need to test the actual failover function of DCS redundant networks in the target environment. The purpose of this study is to verify that the failover functions works correctly in certain abnormal conditions during installation and commissioning phase and identify the influence of network failover on the entire DCS. To quantify the effects of network failover in the DCS, the packets (Protocol Data Units) must be collected and resource usage of the system has to be monitored and analyzed. This study introduces the use of a new methodology for verification of DCS network failover during the installation and commissioning phases. This study is expected to provide insight into verification methodology and the failover effects from DCS redundant networks. It also provides test results of network performance from DCS network failover in digitalized domestic nuclear power plants (NPPs)

  13. “Latin American News Agency Should be Formed…” Las agencias de noticias internacionales en el México posrevolucionario, 1920-1934

    Directory of Open Access Journals (Sweden)

    Sebastián Rivera Mir

    2015-05-01

    Full Text Available En el presente artículo se analizan las agencias de información internacionales vinculadas a los gobiernos posrevolucionarios, entre 1920 y 1934. Este tema no ha sido previamente abordado ni por la historiografía mexicana, ni por los estudios comunicacionales. El objetivo es penetrar en el complejo escenario informativo que se comenzó a construir durante este periodo. Las agencias fueron diseñadas en un contexto donde Estados Unidos realizaba una fuerte campaña propagandística en contra de la revolución mexicana, y los gobiernos de México decidieron contrarrestar esta situación a través de una serie de iniciativas donde las agencias ocuparon un espacio importante. En este escenario se recurrió metodológicamente a la idea de construcción de frentes contrahegemónicos desarrollada por Jorge González. A lo largo de la investigación se distinguieron más de una decena de este tipo de entidades, y se lograron establecer los mecanismos que utilizó el Estado mexicano para desplegar sus objetivos

  14. Psychological factors of professional success of nuclear power plant main control room operators

    Directory of Open Access Journals (Sweden)

    Kosenkov A.A.

    2014-12-01

    Full Text Available Aim: to conduct a comparative analysis of the psychological characteristics of the most and least successful main control room operators. Material and Methods. Two NPP staff groups: the most and least successful main control room operators, who worked in routine operating conditions, were surveyed. Expert evaluation method has been applied to identify the groups. The subjects were administered the Minnesota Multiphasic Personality Inventory (MMPI, Cattell's Sixteen Personality Factor Questionnaire (16PF form A and Raven's Progressive Matrices test. Results. Numerous significant psychological differences between the groups of most and least successful control room operators were obtained: the best operators were significantly more introverted and correctly solved more logical tasks with smaller percentage of mistakes under time pressure than worst ones. Conclusions: 1. The psychodiagnostic methods used in the study were adequate to meet research objective 2. Tendency to introversion, as well as developed the ability to solve logic problems undertime pressure, apparently, are important professional qualities for control room operators. These indicators should be considered in the process of psychological selection and professional guidance of nuclear power plant operators.

  15. Strategy for Migration of Traditional to Hybrid Control Boards in a Nuclear Power Plant

    Energy Technology Data Exchange (ETDEWEB)

    Boring, Ronald Laurids [Idaho National Lab. (INL), Idaho Falls, ID (United States); Joe, Jeffrey Clark [Idaho National Lab. (INL), Idaho Falls, ID (United States); Ulrich, Thomas Anthony [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2014-07-01

    This strategy document describes the NUREG-0711 based human factors engineering (HFE) phases and associated elements required to support design, verification and validation (V&V), and implementation of new digital control room elements in a legacy analog main control room (MCR). Information from previous planning and analysis work serves as the foundation for creating a human-machine interface (HMI) specification for distributed control systems (DCSs) to be implemented as part of nuclear power plant (NPP) modernization. This document reviews ways to take the HMSI specification and use it when migrating legacy displays or designing displays with new functionality. These displays undergo iterative usability testing during the design phase and then an integrated system validation (ISV) in the full-scope control room training simulator. Following successful demonstration of operator performance using the systems during the ISV, the new DCS is implemented at the plant, first in the training simulator and then in the MCR. This document concludes with a sample project plan, including a 15-month timeline from DCS design through implementation. Included is a discussion of how the U.S. Department of Energy’s Human System Simulation Laboratory (HSSL) can be used to support design and V&V activities. This report completes a Level 4 (M4) milestone under the U.S. Department of Energy’s (DOE’s) Light Water Reactor Sustainability (LWRS) Program.

  16. ATCA/AXIe compatible board for fast control and data acquisition in nuclear fusion experiments

    Energy Technology Data Exchange (ETDEWEB)

    Batista, A.J.N., E-mail: toquim@ipfn.ist.utl.pt [Associacao EURATOM/IST, Instituto de Plasmas e Fusao Nuclear - Laboratorio Associado, Instituto Superior Tecnico - Universidade Tecnica de Lisboa, Lisboa (Portugal); Leong, C.; Bexiga, V. [INESC-ID, Lisboa (Portugal); Rodrigues, A.P.; Combo, A.; Carvalho, B.B.; Fortunato, J.; Correia, M. [Associacao EURATOM/IST, Instituto de Plasmas e Fusao Nuclear - Laboratorio Associado, Instituto Superior Tecnico - Universidade Tecnica de Lisboa, Lisboa (Portugal); Teixeira, J.P.; Teixeira, I.C. [INESC-ID, Lisboa (Portugal); Sousa, J.; Goncalves, B.; Varandas, C.A.F. [Associacao EURATOM/IST, Instituto de Plasmas e Fusao Nuclear - Laboratorio Associado, Instituto Superior Tecnico - Universidade Tecnica de Lisboa, Lisboa (Portugal)

    2012-12-15

    Highlights: Black-Right-Pointing-Pointer High performance board for fast control and data acquisition. Black-Right-Pointing-Pointer Large IO channel number per board with galvanic isolation. Black-Right-Pointing-Pointer Optimized for high reliability and availability. Black-Right-Pointing-Pointer Targeted for nuclear fusion experiments with long duration discharges. Black-Right-Pointing-Pointer To be used on the ITER Fast Plant System Controller prototype. - Abstract: An in-house development of an Advanced Telecommunications Computing Architecture (ATCA) board for fast control and data acquisition, with Input/Output (IO) processing capability, is presented. The architecture, compatible with the ATCA (PICMG 3.4) and ATCA eXtensions for Instrumentation (AXIe) specifications, comprises a passive Rear Transition Module (RTM) for IO connectivity to ease hot-swap maintenance and simultaneously to increase cabling life cycle. The board complies with ITER Fast Plant System Controller (FPSC) guidelines for rear IO connectivity and redundancy, in order to provide high levels of reliability and availability to the control and data acquisition systems of nuclear fusion devices with long duration plasma discharges. Simultaneously digitized data from all Analog to Digital Converters (ADC) of the board can be filtered/decimated in a Field Programmable Gate Array (FPGA), decreasing data throughput, increasing resolution, and sent through Peripheral Component Interconnect (PCI) Express to multi-core processors in the ATCA shelf hub slots. Concurrently the multi-core processors can update the board Digital to Analog Converters (DAC) in real-time. Full-duplex point-to-point communication links between all FPGAs, of peer boards inside the shelf, allow the implementation of distributed algorithms and Multi-Input Multi-Output (MIMO) systems. Support for several timing and synchronization solutions is also provided. Some key features are onboard ADC or DAC modules with galvanic isolation

  17. On The Export Control Of High Speed Imaging For Nuclear Weapons Applications

    Energy Technology Data Exchange (ETDEWEB)

    Watson, Scott Avery [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Altherr, Michael Robert [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-09-15

    Since the Manhattan Project, the use of high-speed photography, and its cousins flash radiography1 and schieleren photography have been a technological proliferation concern. Indeed, like the supercomputer, the development of high-speed photography as we now know it essentially grew out of the nuclear weapons program at Los Alamos2,3,4. Naturally, during the course of the last 75 years the technology associated with computers and cameras has been export controlled by the United States and others to prevent both proliferation among non-P5-nations and technological parity among potential adversaries among P5 nations. Here we revisit these issues as they relate to high-speed photographic technologies and make recommendations about how future restrictions, if any, should be guided.

  18. Intelligent software system for the advanced control room of a nuclear power plant

    Energy Technology Data Exchange (ETDEWEB)

    Chang, Soon Heung; Choi, Seong Soo; Park, Jin Kyun; Heo, Gyung Young [Korea Advanced Institute of Science and Technology, Taejon (Korea, Republic of); Kim, Han Gon [Korea Electric Power Research Institute, Taejon (Korea, Republic of)

    1997-12-31

    The intelligent software system for nuclear power plants (NPPs) has been conceptually designed in this study. Its design goals are to operate NPPs in an improved manner and to support operators` cognitive takes. It consists of six major modules such as {sup I}nformation Processing,{sup {sup A}}larm Processing,{sup {sup P}}rocedure Tracking,{sup {sup P}}erformance Diagnosis,{sup a}nd {sup E}vent Diagnosis{sup m}odules for operators and {sup M}alfunction Diagnosis{sup m}odule for maintenance personnel. Most of the modules have been developed for several years and the others are under development. After the completion of development, they will be combined into one system that would be main parts of advanced control rooms in NPPs. 5 refs., 4 figs. (Author)

  19. Using micro saint to predict performance in a nuclear power plant control room

    Energy Technology Data Exchange (ETDEWEB)

    Lawless, M.T.; Laughery, K.R. [Micro Analysis and Design, Inc., Boulder, CO (United States); Persenky, J.J. [Nuclear Regulatory Commission, Washington, DC (United States)

    1995-09-01

    The United States Nuclear Regulatory Commission (NRC) requires a technical basis for regulatory actions. In the area of human factors, one possible technical basis is human performance modeling technology including task network modeling. This study assessed the feasibility and validity of task network modeling to predict the performance of control room crews. Task network models were built that matched the experimental conditions of a study on computerized procedures that was conducted at North Carolina State University. The data from the {open_quotes}paper procedures{close_quotes} conditions were used to calibrate the task network models. Then, the models were manipulated to reflect expected changes when computerized procedures were used. These models` predictions were then compared to the experimental data from the {open_quotes}computerized conditions{close_quotes} of the North Carolina State University study. Analyses indicated that the models predicted some subsets of the data well, but not all. Implications for the use of task network modeling are discussed.

  20. A Study of BUS Architecture Design for Controller of Nuclear Power Plant Using FPGA

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Dongil; Yun, Donghwa; Hwang, Sungjae; Kim, Myeongyun; Lee, Dongyun [PONUTech Co. Ltd., Seoul (Korea, Republic of)

    2014-05-15

    CPU (Central Processing Unit) operating speed and communication rate have been more technically improved than before. However, whole system is been a degradation of performance by electronic and structural limitation of parallel bus. Transmission quantity and speed have a limit and need arbiter in order to do arbitration because several boards shared parallel bus. Arbiter is a high complexity in implementing so it increases component per chip. If a parallel bus uses, it will occurs some problems what are reflection noise, power/ground noise (or ground bounce) as SSN (Simultaneous Switching Noise) and crosstalk noise like magnetic coupling. In this paper, in order to solve a problem of parallel bus in controller of NPP (Nuclear Power Plant), proposes the bus architecture design using FPGA (Field Programmable Gate Array) based on LVDS (Low Voltage Differential Signaling)

  1. Team interaction skills evaluation criteria for nuclear power plant control room operators

    Energy Technology Data Exchange (ETDEWEB)

    Montgomery, J.C. [Pacific Northwest Lab., Richland, WA (United States); Toquam, J. [Battelle Human Affairs Research Center, Seattle, WA (United States); Gaddy, C. [General Physics Corp., Columbia, MD (United States)

    1991-09-01

    Previous research has shown the value of good team interaction skills to group performance, yet little progress has been made on in terms of how such skills can be measured. In this study rating scales developed previously (Montgomery, et al., 1990) were extensively revised and cast into a Behaviorally Anchored Rating Scale (BARS) and a Behavioral Frequency format. Rating data were collected using 13 training instructors at the Diablo Canyon Nuclear Plant, who rated three videotapes of simulator scenario performance during a day-long training session and later evaluated control room crews during requalification training. High levels of interrater agreement on both rating scales were found. However, the factor structure of the ratings was generally inconsistent with that hypothesized. Analysis of training ratings using Cronbach`s components of accuracy (Cronbach, 1955) indicated that BARS ratings generally exhibited less error than did the Behavioral Frequency ratings. The results are discussed in terms of both field and research implications.

  2. Aging Management Guideline for commercial nuclear power plants: Motor control centers; Final report

    Energy Technology Data Exchange (ETDEWEB)

    Toman, G.; Gazdzinski, R.; O`Hearn, E. [Ogden Environmental and Energy Services Co., Inc., Blue Bell, PA (United States)

    1994-02-01

    This Aging Management Guideline (AMG) provides recommended methods for effective detection and mitigation of age-related degradation mechanisms in Boiling Water Reactor (BWR) and Pressurized Water Reactor (PWR) commercial nuclear power plant motor control centers important to license renewal. The intent of this AMG is to assist plant maintenance and operations personnel in maximizing the safe, useful life of these components. It also supports the documentation of effective aging management programs required under the License Renewal Rule 10 CFR Part 54. This AMG is presented in a manner that allows personnel responsible for performance analysis and maintenance to compare their plant-specific aging mechanisms (expected or already experienced) and aging management program activities to the more generic results and recommendations presented herein.

  3. International training course on implementation of state systems of accounting for and control of nuclear materials: proceedings

    Energy Technology Data Exchange (ETDEWEB)

    1984-06-01

    This report incorporates all lectures and presentations at the International Training Course on Implementation of State Systems of Accounting for and Control of Nuclear Materials held October 17 through November 4, 1983, at Santa Fe and Los Alamos, New Mexico and Richland, Washington, USA. Authorized by the US Nuclear Non-Proliferation Act and sponsored by the US Department of Energy in cooperation with the International Atomic Energy Agency, the course was developed to provide practical training in the design, implementation, and operation of a State system of nuclear materials accountability and control that satisfies both national and international safeguards requirements. Major emphasis for the 1983 course was placed on safeguards methods used at bulk-handling facilities, particularly low-enriched uranium conversion and fuel fabrication plants. The course was conducted by the University of California's Los Alamos National Laboratory and Exxon Nuclear Company, Inc. Tours and demonstrations were arranged at the Los Alamos National Laboratory, Los Alamos, New Mexico, and the Exxon Nuclear fuel fabrication plant, the Battelle Pacific Northwest Laboratory, Westinghouse Fast Flux Test Facility Visitor Center, and Washington Public Power System nuclear reactor facilities in Richland, Washington. Individual presentations were indexed for inclusion in the Energy Data Base.

  4. Evaluation of nitrogen containing reducing agents for the corrosion control of materials relevant to nuclear reactors

    Energy Technology Data Exchange (ETDEWEB)

    Kumar, Padma S. [Water and Steam Chemistry Division, BARC Facilities, Kalpakkam, Tamilnadu (India); Mohan, D. [Department of Chemistry, Anna University, Chennai, Tamilnadu (India); Chandran, Sinu; Rajesh, Puspalata; Rangarajan, S. [Water and Steam Chemistry Division, BARC Facilities, Kalpakkam, Tamilnadu (India); Velmurugan, S., E-mail: svelu@igcar.gov.in [Water and Steam Chemistry Division, BARC Facilities, Kalpakkam, Tamilnadu (India)

    2017-02-01

    Materials undergo enhanced corrosion in the presence of oxidants in aqueous media. Usually, hydrogen gas or water soluble reducing agents are used for inhibiting corrosion. In the present study, the feasibility of using alternate reducing agents such as hydrazine, aqueous ammonia, and hydroxylamine that can stay in the liquid phase was investigated. A comparative study of corrosion behavior of the structural materials of the nuclear reactor viz. carbon steel (CS), stainless steel (SS-304 LN), monel-400 and incoloy-800 in the oxidizing and reducing conditions was also made. In nuclear industry, the presence of radiation field adds to the corrosion problems. The radiolysis products of water such as oxygen and hydrogen peroxide create an oxidizing environment that enhances the corrosion. Electrochemical studies at 90 °C showed that the reducing agents investigated were efficient in controlling corrosion processes in the presence of oxygen and hydrogen peroxide. Evaluation of thermal stability of hydrazine and its effect on corrosion potential of SS-304 LN were also investigated in the temperature range of 200–280 °C. The results showed that the thermal decomposition of hydrazine followed a first order kinetics. Besides, a change in electrochemical corrosion potential (ECP) was observed from −0.4 V (Vs SHE) to −0.67 V (Vs SHE) on addition of 5 ppm of hydrazine at 240 °C. Investigations were also made to understand the distribution behavior of hydrogen peroxide and hydrazine in water-steam phases and it was found that both the phases showed identical behavior. - Highlights: • Hydrazine was found to be a promising reducing agent for oxidant control. • In presence of hydrazine corrosion potential of SS304 LN was well below −230 mV. • SS304LN could be protected from IGSCC by hydrazine addition. • Thermal and radiation stability of hydrazine at 285 °C was found satisfactory.

  5. Virus-Induced Chaperone-Enriched (VICE domains function as nuclear protein quality control centers during HSV-1 infection.

    Directory of Open Access Journals (Sweden)

    Christine M Livingston

    2009-10-01

    Full Text Available Virus-Induced Chaperone-Enriched (VICE domains form adjacent to nuclear viral replication compartments (RC during the early stages of HSV-1 infection. Between 2 and 3 hours post infection at a MOI of 10, host protein quality control machinery such as molecular chaperones (e.g. Hsc70, the 20S proteasome and ubiquitin are reorganized from a diffuse nuclear distribution pattern to sequestration in VICE domains. The observation that VICE domains contain putative misfolded proteins suggests that they may be similar to nuclear inclusion bodies that form under conditions in which the protein quality control machinery is overwhelmed by the presence of misfolded proteins. The detection of Hsc70 in VICE domains, but not in nuclear inclusion bodies, indicates that Hsc70 is specifically reorganized by HSV-1 infection. We hypothesize that HSV-1 infection induces the formation of nuclear protein quality control centers to remodel or degrade aberrant nuclear proteins that would otherwise interfere with productive infection. Detection of proteolytic activity in VICE domains suggests that substrates may be degraded by the 20S proteasome in VICE domains. FRAP analysis reveals that GFP-Hsc70 is dynamically associated with VICE domains, suggesting a role for Hsc70 in scanning the infected nucleus for misfolded proteins. During 42 degrees C heat shock, Hsc70 is redistributed from VICE domains into RC perhaps to remodel viral replication and regulatory proteins that have become insoluble in these compartments. The experiments presented in this paper suggest that VICE domains are nuclear protein quality control centers that are modified by HSV-1 to promote productive infection.

  6. The impact of the instrumentation and control systems in the safety of a nuclear plant: a general vision; El impacto de los sistemas de instrumentacion y control en la seguridad de una planta nuclear: una vision general

    Energy Technology Data Exchange (ETDEWEB)

    Celis del Angel, L.; Rivero, T., E-mail: lina.celis@inin.gob.mx [ININ, Carretera Mexico-Toluca s/n, 52750 Ocoyoacac, Estado de Mexico (Mexico)

    2011-11-15

    One of the fundamental components so much for the sure operation, like in emergency cases or accident are the equipment s and instrumentation and control systems. The nuclear industry has had some accidents where the instrumentation and control have played and important part: a wrong design, instrumentation lack, faulty systems of safety, etc. At the present time the necessity to modernize the instrumentation and control in a nuclear power plant is before the challenge of finding innovative forms to improve the competitiveness and readiness, reducing operation costs without put ing in risk the safety and reliability of the nuclear power plant. Most of the nuclear power plants require actualizing their instrumentation and control systems, here the digital systems represent a great alternative, improving the performance and the safety, increasing the readiness and reducing the maintenance s. However they require of strict tests that allow assuring their application in critical systems. It is also necessary, the development of modernization programs that allow the programmed substitution of the systems without affecting the readiness of the nuclear power plants. During this whole modernization process will be necessary to put special attention in the cyber-safety because the attacks every time they are more elaborated. Therefore will be necessary to go toward the modernization of the instrumentation and control with the challenge of making without detriment some in the safety of the normal operation and with response reliability in emergency conditions or accident that which represents an effort that should not be postponed in the case of the nuclear power plant of Laguna Verde. (Author)

  7. Transcriptional Regulation by Nuclear Corepressors and PGC-1α: Implications for Mitochondrial Quality Control and Insulin Sensitivity

    Directory of Open Access Journals (Sweden)

    Zhengtang Qi

    2012-01-01

    Full Text Available The peroxisome proliferator-activated receptors (PPARs and estrogen-related receptor (ERRα are ligand-activated nuclear receptors that coordinately regulate gene expression. Recent evidence suggests that nuclear corepressors, NCoR, RIP140, and SMRT, repress nuclear receptors-mediated transcriptional activity on specific promoters, and thus regulate insulin sensitivity, adipogenesis, mitochondrial number, and activity in vivo. Moreover, the coactivator PGC-1α that increases mitochondrial biogenesis during exercise and calorie restriction directly regulates autophagy in skeletal muscle and mitophagy in the pathogenesis of Parkinson's disease. In this paper, we discuss the PGC-1α’s novel role in mitochondrial quality control and the role of nuclear corepressors in regulating insulin sensitivity and interacting with PGC-1α.

  8. Grafía, el trabajo en una agencia de prensa especializada en infográficos (6

    Directory of Open Access Journals (Sweden)

    Julio Alonso

    1998-01-01

    Full Text Available El periodista gráfico Julio Alonso conoció los 'secretos' de la infografía en el diario 'El País' (Madrid y después se ocupó de la dirección de arte de la Agencia Grafía, la primera entidad de este tipo dedicada a la realización de infografía para medios impresos. El trabajo aquí presentado data del periodo en que Alonso trabajó en Grafía y corresponde a la lección impartida en el curso sobre infografía periodística celebrado en la Universidad Internacional Menéndez y Pelayo, en su sede de Cuenca. Se trata de la sexta entrega del libro colectivo sobre infografía periodística, iniciado por Mario R. García, del Poynter Institute de Florida (EE.UU., y continuado por Elio Leturia, grafista del diario norteamericano The Detroit Free Press; por el catedrático de Periodismo José Manuel de Pablos, de la Universidad de La Laguna (Canarias; el ex director de arte del diario Le Monde (París, Michel Gafré, y el profesor Kevin G. Barnhurst, de la Siracuse University.

  9. The Quantometer as an analytical instrument in the control of nuclear materials; El cuantometro como instrumento analitico en el control de materiales nucleares

    Energy Technology Data Exchange (ETDEWEB)

    Alvarez Gonzalez, F.; Roca Adell, M.; Fernandez Cellini, R.

    1961-07-01

    In order to solve different problems of chemical analysis in the fields of nuclear industry and research, a Quantometer is used with a high number of channels. A detailed study to choose the more suitable spectral lines is described. The different channels have been distributed into two programs to allow the analysis of high and low concentrations. The Quantometer is being applied successfully to analyse soils, plant ashes, rocks and ores, uranium and its compounds, zirconium, graphite, alloys and other nuclear materials. (Author) 6 refs.

  10. Page 1 . Bull, Mater. Sci., Vol. 15, No. 6, December 1992, pp. 543 ...

    Indian Academy of Sciences (India)

    -based alloys have been in use in the nuclear and chemical industries for quite some time. Considerable improvement in properties of zirconium-based alloys has been achieved by suitable modification of alloy compositions. In addition to.

  11. The Programmable Logic Controller and its application in nuclear reactor systems

    Energy Technology Data Exchange (ETDEWEB)

    Palomar, J.; Wyman, R. [Lawrence Livermore National Lab., CA (United States)

    1993-09-01

    This document provides recommendations to guide reviewers in the application of Programmable Logic Controllers (PLCS) to the control, monitoring and protection of nuclear reactors. The first topics addressed are system-level design issues, specifically including safety. The document then discusses concerns about the PLC manufacturing organization and the protection system engineering organization. Supplementing this document are two appendices. Appendix A summarizes PLC characteristics. Specifically addressed are those characteristics that make the PLC more suitable for emergency shutdown systems than other electrical/electronic-based systems, as well as characteristics that improve reliability of a system. Also covered are PLC characteristics that may create an unsafe operating environment. Appendix B provides an overview of the use of programmable logic controllers in emergency shutdown systems. The intent is to familiarize the reader with the design, development, test, and maintenance phases of applying a PLC to an ESD system. Each phase is described in detail and information pertinent to the application of a PLC is pointed out.

  12. Measuring Situation Awareness of Operating Team in Different Main Control Room Environments of Nuclear Power Plants

    Directory of Open Access Journals (Sweden)

    Seung Woo Lee

    2016-02-01

    Full Text Available Environments in nuclear power plants (NPPs are changing as the design of instrumentation and control systems for NPPs is rapidly moving toward fully digital instrumentation and control, and modern computer techniques are gradually introduced into main control rooms (MCRs. Within the context of these environmental changes, the level of performance of operators in a digital MCR is a major concern. Situation awareness (SA, which is used within human factors research to explain to what extent operators of safety-critical systems know what is transpiring in the system and the environment, is considered a prerequisite factor to guarantee the safe operation of NPPs. However, the safe operation of NPPs can be guaranteed through a team effort. In this regard, the operating team's SA in a conventional and digital MCR should be measured in order to assess whether the new design features implemented in a digital MCR affect this parameter. This paper explains the team SA measurement method used in this study and the results of applying this measurement method to operating teams in different MCR environments. The paper also discusses several empirical lessons learned from the results.

  13. International training course on implementation of state systems of accounting for and control of nuclear materials: proceedings

    Energy Technology Data Exchange (ETDEWEB)

    1986-06-01

    This report incorporates all lectures and presentations at the International Training Course on Implementation of State Systems of Accounting for and Control of Nuclear Materials held June 3 through June 21, 1985, at Santa Fe and Los Alamos, New Mexico, and San Clemente, California. Authorized by the US Nuclear Non-Proliferation Act and sponsored by the US Department of Energy in cooperation with the International Atomic Energy Agency, the Course was developed to provide practical training in the design, implementation, and operation of a state system of nuclear materials accountability and control that satisfies both national and international safeguards requirements. Major emphasis for the 1985 course was placed on safeguards methods used at item-control facilities, particularly nuclear power generating stations and test reactors. An introduction to safeguards methods used at bulk handling facilities, particularly low-enriched uranium conversion and fuel fabrication plants, was also included. The course was conducted by the University of California's Los Alamos National Laboratory and the Southern California Edison Company. Tours and demonstrations were arranged at the Los Alamos National Laboratory, Los Alamos, New Mexico, and the San Onofre Nuclear Generating Station, San Clemente, California.

  14. Laser bonding with ICG-infused chitosan patches: preliminary experiences in suine dura mater and vocal folds

    Science.gov (United States)

    Rossi, Francesca; Matteini, Paolo; Ratto, Fulvio; Pini, Roberto; Iacoangeli, Maurizio; Giannoni, Luca; Fortuna, Damiano; Di Cicco, Emiliano; Corbara, Sylwia; Dallari, Stefano

    2014-05-01

    Laser bonding is a promising minimally invasive approach, emerging as a valid alternative to conventional suturing techniques. It shows widely demonstrated advantages in wound treatment: immediate closuring effect, minimal inflammatory response and scar formation, reduced healing time. This laser based technique can overcome the difficulties in working through narrow surgical corridors (e.g. the modern "key-hole" surgery as well as the endoscopy setting) or in thin tissues that are impossible to treat with staples and/or stitches. We recently proposed the use of chitosan matrices, stained with conventional chromophores, to be used in laser bonding of vascular tissue. In this work we propose the same procedure to perform laser bonding of vocal folds and dura mater repair. Laser bonding of vocal folds is proposed to avoid the development of adhesions (synechiae), after conventional or CO2 laser surgery. Laser bonding application in neurosurgery is proposed for the treatment of dural defects being the Cerebro Spinal Fluid leaks still a major issue. Vocal folds and dura mater were harvested from 9-months old porks and used in the experimental sessions within 4 hours after sacrifice. In vocal folds treatment, an IdocyanineGreen-infused chitosan patch was applied onto the anterior commissure, while the dura mater was previously incised and then bonded. A diode laser emitting at 810 nm, equipped with a 600 μm diameter optical fiber was used to weld the patch onto the tissue, by delivering single laser spots to induce local patch/tissue adhesion. The result is an immediate adhesion of the patch to the tissue. Standard histology was performed, in order to study the induced photothermal effect at the bonding sites. This preliminary experimental activity shows the advantages of the proposed technique in respect to standard surgery: simplification of the procedure; decreased foreign-body reaction; reduced inflammatory response; reduced operating times and better handling in

  15. Development of uranium reference particles for nuclear safeguards and non-proliferation control

    Science.gov (United States)

    Kips, Ruth

    In the oversight of the nuclear Non-Proliferation Treaty and as part of the Additional Protocol of the International Atomic Energy Agency, environmental sampling has become an important tool for the detection of non-declared nuclear activities. One extensively developed technique in environmental sampling (ES) makes use of pieces of cotton cloth called swipes to wipe surfaces in and around a nuclear facility. The dust collected on these swipes typically contains micrometer-sized uranium particles with an isotopic composition characteristic for the processes at the inspected facility. Since its implementation in the 1990s, ES has proven to be a very effective tool in the detection of clandestine activities owing to a number of highly sensitive and selective techniques, including secondary ion mass spectrometry and thermal ionisation mass spectrometry. However, considering the potential consequences of the analyses, these measurements need to be subjected to a rigorous quality management system. In a continuous effort to improve the accuracy and detection efficiency of the uranium isotope ratio measurements, uranium particle reference materials are being developed by different research groups. It was concluded however, that the existing methods for the production of particulate reference materials generally do not reproduce the particles recovered from swipe samples. For this reason, we developed the aerosol deposition chamber at the Institute for Reference Materials and Measurements for the production of reference uranium particles that are representative of the particles collected at enrichment facilities. This method is based on the controlled hydrolysis of milligram amounts of uranium hexafluoride with a certified uranium isotopic composition. After optimization of the experimental set-up, the particles produced by the aerosol deposition chamber were characterized by scanning electron microscopy, transmission electron microscopy, micro-Raman spectroscopy and

  16. Nuclear Rocket Facility Decommissioning Project: Controlled Explosive Demolition of Neutron-Activated Shield Wall

    Energy Technology Data Exchange (ETDEWEB)

    Michael R. Kruzic

    2008-06-01

    Located in Area 25 of the Nevada Test Site (NTS), the Test Cell A (TCA) Facility (Figure 1) was used in the early to mid-1960s for testing of nuclear rocket engines, as part of the Nuclear Rocket Development Program, to further space travel. Nuclear rocket testing resulted in the activation of materials around the reactors and the release of fission products and fuel particles. The TCA facility, known as Corrective Action Unit 115, was decontaminated and decommissioned (D&D) from December 2004 to July 2005 using the Streamlined Approach for Environmental Restoration (SAFER) process, under the Federal Facility Agreement and Consent Order. The SAFER process allows environmental remediation and facility closure activities (i.e., decommissioning) to occur simultaneously, provided technical decisions are made by an experienced decision maker within the site conceptual site model. Facility closure involved a seven-step decommissioning strategy. First, preliminary investigation activities were performed, including review of process knowledge documentation, targeted facility radiological and hazardous material surveys, concrete core drilling and analysis, shield wall radiological characterization, and discrete sampling, which proved to be very useful and cost-effective in subsequent decommissioning planning and execution and worker safety. Second, site setup and mobilization of equipment and personnel were completed. Third, early removal of hazardous materials, including asbestos, lead, cadmium, and oil, was performed ensuring worker safety during more invasive demolition activities. Process piping was to be verified void of contents. Electrical systems were de-energized and other systems were rendered free of residual energy. Fourth, areas of high radiological contamination were decontaminated using multiple methods. Contamination levels varied across the facility. Fixed beta/gamma contamination levels ranged up to 2 million disintegrations per minute (dpm)/100

  17. NUCLEAR-MAGNETIC MINI-RELAXOMETER FOR LIQUID AND VISCOUS MEDIA CONTROL

    Directory of Open Access Journals (Sweden)

    V. V. Davydov

    2015-01-01

    Full Text Available The paper deals with a new method for registration of nuclear magnetic resonance signal of small volume liquid and viscous media being studied (0.5 ml in a weak magnetic field (0.06 –0.08 T, and measuring of longitudinal T1 and transverse T2 relaxation constants. A new construction of NMR mini-relaxometer magnetic system is developed for registration of NMR signal. The nonuniformity of a magnetic field in a pole where registration coil is located is 0,410–3 sm–1 (the induction is В0 = 0.079 T. An electrical circuit of autodyne receiver (weak fluctuations generator has been developed with usage of low noise differential amplifier and NMR signal operating and control scheme (based on microcontroller STM32 for measuring of relaxation constants of liquid and viscous media in automatic operating mode. New technical decisions made it possible to improve relaxometer response time and dynamic range of measurements for relaxation constants T1 and T2 in comparison with small sized nuclear-magnetic spectrometer developed by the authors earlier (with accuracy characteristics conservation. The developed schemes for self-tuning of registration frequency, generating amplitude of magnetic field H1 in registration coil, and amplitude and frequency of modulating field provide measuring of T1 and T2 with error less than 0.5 % and signal to noise ratio about 1.2 in temperature range from 3 to 400 C. A new construction of mini-relaxometer reduced the weight of the device to 4 kg (with independent supply unit and increased transportability and operating convenience.

  18. Standard guide for application of radiation monitors to the control and physical security of special nuclear material

    CERN Document Server

    American Society for Testing and Materials. Philadelphia

    1999-01-01

    1.1 This guide briefly describes the state-of-the-art of radiation monitors for detecting special nuclear material (SNM) (see 3.1.11) in order to establish the context in which to write performance standards for the monitors. This guide extracts information from technical documentation to provide information for selecting, calibrating, testing, and operating such radiation monitors when they are used for the control and protection of SNM. This guide offers an unobtrusive means of searching pedestrians, packages, and motor vehicles for concealed SNM as one part of a nuclear material control or security plan for nuclear materials. The radiation monitors can provide an efficient, sensitive, and reliable means of detecting the theft of small quantities of SNM while maintaining a low likelihood of nuisance alarms. 1.2 Dependable operation of SNM radiation monitors rests on selecting appropriate monitors for the task, operating them in a hospitable environment, and conducting an effective program to test, calibrat...

  19. Liver glucokinase gene expression is controlled by the onecut transcription factor hepatocyte nuclear factor-6.

    Science.gov (United States)

    Lannoy, V J; Decaux, J F; Pierreux, C E; Lemaigre, F P; Rousseau, G G

    2002-08-01

    Glucokinase plays a key role in glucose homeostasis and the expression of its gene is differentially regulated in pancreatic beta cells and in the liver through distinct promoters. The factors that determine the tissue-specific expression of the glucokinase gene are not known. Putative binding sites for hepatocyte nuclear factor (HNF)-6, the prototype of the ONECUT family of transcription factors, are present in the hepatic promoter of the glucokinase gene and hnf6 knockout mice are diabetic [corrected]. We hypothesized that HNF-6 controls the activity of the hepatic glucokinase promoter. We tested the binding of recombinant HNF-6 to DNA sequences from the mouse hepatic glucokinase promoter in vitro and the effect of HNF-6 on promoter activity in transfected cells. We investigated in vivo the role of HNF-6 in mice by examining the effect of inactivating the hnf6 gene on glucokinase gene-specific deoxyribonuclease I hypersensitive sites in liver chromatin and on liver glucokinase mRNA concentration. HNF-6 bound to the hepatic promoter of the glucokinase gene and stimulated its activity. Inactivation of the hnf6 gene did not modify the pattern of deoxyribonuclease I hypersensitive sites but was associated with a decrease of liver glucokinase mRNA to half the control value. Although HNF-6 is not required to open chromatin of the hepatic promoter of the glucokinase gene, it stimulates transcription of the glucokinase gene in the liver. This could partly explain the diabetes observed in hnf6 knockout mice.

  20. Research and development on the application of advanced control technologies to advanced nuclear reactor systems: A US national perspective

    Energy Technology Data Exchange (ETDEWEB)

    White, J.D.; Monson, L.R.; Carrol, D.G.; Dayal, Y. (Oak Ridge National Lab., TN (USA); Argonne National Lab., IL (USA); General Electric Co., San Jose, CA (USA))

    1989-01-01

    Control system designs for nuclear power plants are becoming more advanced through the use of digital technology and automation. This evolution is taking place because of: (1) the limitations in analog based control system performance and maintenance and availability and (2) the promise of significant improvement in plant operation and availability due to advances in digital and other control technologies. Digital retrofits of control systems in US nuclear plants are occurring now. Designs of control and protection systems for advanced LWRs are based on digital technology. The use of small inexpensive, fast, large-capacity computers in these designs is the first step of an evolutionary process described in this paper. Under the sponsorship of the US Department of Energy (DOE), Oak Ridge National Laboratory, Argonne National Laboratory, GE Nuclear Energy and several universities are performing research and development in the application of advances in control theory, software engineering, advanced computer architectures, artificial intelligence, and man-machine interface analysis to control system design. The target plant concept for the work described in this paper is the Power Reactor Inherently Safe Module reactor (PRISM), an advanced modular liquid metal reactor concept. This and other reactor designs which provide strong passive responses to operational upsets or accidents afford good opportunities to apply these advances in control technology. 18 refs., 5 figs.

  1. Components of the Arabidopsis nuclear pore complex play multiple diverse roles in control of plant growth.

    Science.gov (United States)

    Parry, Geraint

    2014-11-01

    The nuclear pore complex (NPC) is a multisubunit protein conglomerate that facilitates movement of RNA and protein between the nucleus and cytoplasm. Relatively little is known regarding the influence of the Arabidopsis NPC on growth and development. Seedling development, flowering time, nuclear morphology, mRNA accumulation, and gene expression changes in Arabidopsis nucleoporin mutants were investigated. Nuclear export of mRNA is differentially affected in plants with defects in nucleoporins that lie in different NPC subcomplexes. This study reveals differences in the manner by which nucleoporins alter molecular and plant growth phenotypes, suggesting that nuclear pore subcomplexes play distinct roles in nuclear transport and reveal a possible feedback relationship between the expression of genes involved in nuclear transport. © The Author 2014. Published by Oxford University Press on behalf of the Society for Experimental Biology.

  2. Seismic risk control of nuclear power plants using seismic protection systems in stable continental regions: The UK case

    Energy Technology Data Exchange (ETDEWEB)

    Medel-Vera, Carlos, E-mail: cbmedel@uc.cl; Ji, Tianjian, E-mail: tianjian.ji@manchester.ac.uk

    2016-10-15

    Highlights: • Strategies to reduce seismic risk for nuclear power stations in the UK are analysed. • Efficiency of devices to reduce risk: viscous-based higher than hysteretic-based. • Scenario-based incremental dynamic analysis is introduced for use in nuclear stations. • Surfaces of seismic unacceptable performance for nuclear stations are proposed. - Abstract: This article analyses three different strategies on the use of seismic protection systems (SPS) for nuclear power plants (NPPs) in the UK. Such strategies are based on the experience reported elsewhere of seismically protected nuclear reactor buildings in other stable continental regions. Analyses are conducted using an example of application based on a 1000 MW Pressurised Water Reactor building located in a representative UK nuclear site. The efficiency of the SPS is probabilistically assessed to achieve possible risk reduction for both rock and soil sites in comparison with conventionally constructed NPPs. Further analyses are conducted to study how the reduction of risk changes when all controlling scenarios of the site are included. This is done by introducing a scenario-based incremental dynamic analysis aimed at the generation of surfaces for unacceptable performance of NPPs as a function of earthquake magnitude (M{sub w}) and distance-to-site (R{sub epi}). General guidelines are proposed to potentially use SPS in future NPPs in the UK. Such recommendations can be used by the British nuclear industry in the future development of 12 new reactors to be built in the next two decades to generate 16 GWe of new nuclear capacity.

  3. Contribuição para a história da profissão contabilística em Portugal: o primeiro guarda-livros com diploma escolar (1771

    Directory of Open Access Journals (Sweden)

    Miguel Gonçalves

    2017-07-01

    Full Text Available O trabalho introduz na historiografia contabilística o nome de um agente português que ajudou a disseminar as partidas dobradas em Portugal e divulga, comentando criticamente, a versão manuscrita original daquele que se crê ser o primeiro diploma de curso de um guarda-livros português. O profissional em questão, Felix Potier (1741-1790, um português nascido em Lisboa, filho de um negociante francês aí radicado, formou-se em 1763, mas apenas em 1771 terá requerido o seu diploma de curso. Potier foi um dos primeiros 61 alunos da Aula do Comércio, escola de contabilidade fundada em 1759 em Lisboa por Sebastião José de Carvalho e Melo, mais conhecido pelo seu título nobiliárquico de Marquês de Pombal (1770. Dos 61 alunos matriculados aquando da inauguração da escola, apenas 31 terão pedido à Junta do Comércio o seu diploma de conclusão de curso. E, tudo assim o indica, apenas uma dessas cartas de curso certificadoras das habilitações literárias obtidas na Aula do Comércio sobreviveu à inexorável passagem do tempo; aquela que este artigo intenta mostrar à comunidade, datada de 10 de janeiro de 1771, emitida pela Junta do Comércio, a instituição governamental a quem cabia a incumbência de gerir a escola. Potier iniciou o seu percurso profissional no Erário Régio (1763-1767 e depois, em 1767, começou a sua atividade no Colégio Real dos Nobres, instituição na qual foi o responsável pela contabilidade durante mais de 20 anos. As conclusões apoiam-se em fontes primárias de investigação, em legislação e em recursos secundários. O artigo contribui para a literatura com informação que permite um novo verbete no Dicionário de Professores e Alunos das Aulas de Comércio (1974, compêndio de Francisco Santana, cuja atualização se julga muito útil para a história da contabilidade lusófona. O estudo adiciona, bem assim, outros novos elementos ao conhecimento em geral e ao conhecimento da história da

  4. Nuclear Safety

    Energy Technology Data Exchange (ETDEWEB)

    Silver, E G [ed.

    1989-01-01

    This document is a review journal that covers significant developments in the field of nuclear safety. Its scope includes the analysis and control of hazards associated with nuclear energy, operations involving fissionable materials, and the products of nuclear fission and their effects on the environment. Primary emphasis is on safety in reactor design, construction, and operation; however, the safety aspects of the entire fuel cycle, including fuel fabrication, spent-fuel processing, nuclear waste disposal, handling of radioisotopes, and environmental effects of these operations, are also treated.

  5. Simulator of Cryogenic process and Refrigeration, and its Control in scientific -nuclear facilities with EcosimPro; Simulador de procesos criogenicos y de refrigeracion y de su control en las grandes instalaciones cienfificas nucleares con Ecosimpro

    Energy Technology Data Exchange (ETDEWEB)

    Veleiro Blanco, A. M.

    2011-07-01

    The cryogenic plants and their control in Scientific-Nuclear Facilities is complicated by the large number of variables and the wide range of variation during operation. Initially the design and control of these systems in CERN was based on stationary calculations which non yielded the expected results. Due to its complexity, the dynamic simulation is the only way to get adequate results during operational transients.

  6. Dynamical nuclear polarization using multi-colour control of color centers in diamond

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Pengcheng [Huazhong University of Science and Technology, School of Physics, Wuhan (China); Huazhong University of Science and Technology, Center for Quantum Optical Science, Wuhan (China); Plenio, Martin B. [Universitaet Ulm, Institut fuer Theoretische Physik, Ulm (Germany); Universitaet Ulm, Center for Integrated Quantum Science and Technology, Ulm (Germany); Cai, Jianming [Huazhong University of Science and Technology, School of Physics, Wuhan (China); Huazhong University of Science and Technology, Center for Quantum Optical Science, Wuhan (China); Universitaet Ulm, Institut fuer Theoretische Physik, Ulm (Germany); Universitaet Ulm, Center for Integrated Quantum Science and Technology, Ulm (Germany)

    2016-12-15

    Dynamical nuclear polarization (DNP) transfers the polarization of electron spins at cryogenic temperatures to achieve strong nuclear polarization for applications in nuclear magnetic resonance. Recently introduced approaches employ optical pumping of nitrogen-vacancy (NV) centers in diamond to achieve DNP even at ambient temperatures. In such schemes microwave radiation is used to establish a Hartmann-Hahn condition between the NV electron spin and proximal nuclear spins to facilitate polarization transfer. For a single monochromatic microwave driving field, the Hartmann-Hahn condition cannot be satisfied for an ensemble of NV centers due to inhomogeneous broadening and reduces significantly the overall efficiency of dynamical nuclear polarization using an ensemble of NV centers. Here, we adopt generalized Hartmann-Hahn type dynamical nuclear polarization schemes by applying microwave driving fields with (multiple) time-modulated frequencies. We show that it is possible to enhance the effective coupling between an ensemble of NV center spins with inhomogeneous broadening and nuclear spins, thereby improving significantly the overall efficiency of dynamical nuclear polarization. This approach can also be used to achieve dynamical nuclear polarization of an ensemble of nuclei with a distribution of Larmor frequencies, which would be helpful in magnetic resonance spectroscopy using a single NV spin sensor. (orig.)

  7. Case-control study on childhood cancer in the vicinity of nuclear power plants in Germany 1980-2003.

    Science.gov (United States)

    Spix, Claudia; Schmiedel, Sven; Kaatsch, Peter; Schulze-Rath, Renate; Blettner, Maria

    2008-01-01

    The 1984 Windscale study raised concern about a possible association between living in the vicinity of nuclear power plants and childhood cancer. No such effect for all cancers was seen in ecological studies in Germany (1980-1995). Results from exploratory analyses led to a new study. Pre-selected areas around all 16 major nuclear power plants in Germany formed the study area. The design is a matched case-control study; cases are all cancers under five years diagnosed in 1980-2003: 1592 cases, and 4735 controls. Inverse distance of place of residence to the nearest nuclear power plant at the time of diagnosis was used as the independent variable in a conditional logistic regression model. Results show an increased risk for childhood cancer under five years when living near nuclear power plants in Germany. The inner 5-km zone shows an increased risk (odds ratio 1.47; lower one-sided 95% confidence limit 1.16). The effect was largely restricted to leukaemia. The results are compatible with the corresponding subgroups in the previous German ecological studies, with which this study shares most of the cases. They contrast with the lack of an effect observed or expected from other studies due to low doses from routine nuclear power plant operation.

  8. Characterization and morphological comparison of human dura mater, temporalis fascia, and pericranium for the correct selection of an autograft in duraplasty procedures.

    Science.gov (United States)

    Morales-Avalos, Rodolfo; Soto-Domínguez, Adolfo; García-Juárez, Jaime; Saucedo-Cardenas, Odila; Bonilla-Galvan, José R; Cardenas-Serna, Marcela; Guzmán-López, Santos; Elizondo-Omaña, Rodrigo E

    2017-01-01

    The objective of this study was to characterize and compare the morphological characteristics of the dura mater, the pericranium, and the temporal fascia to ascertain the most adequate tissue to use as a dura graft. 20 dura mater, 20 pericranium and 20 temporalis fascia samples were analyzed. Each of the samples was stained with hematoxylin and eosin, orcein, Van Gieson, Masson's trichrome and Verhoeff-Van Gieson (600 slides in total) for a general morphological evaluation, as well as a quantitative, morphometric and densitometric analysis of elastic fibers present in each of the tissues. The micro-densitometric analysis of the tissues indicated that the area occupied by the elastic fibers showed values of 1.766 ± 1.376, 4.580 ± 3.041, and 8.253 ± 4.467 % for the dura mater, the temporalis fascia and the pericranium, respectively (p fascia and the pericranium, respectively (p fascia and dura mater vs. pericranium). This is the first study to compare the dura mater with tissues for dural autograft and to quantify the elastic component present in these tissues. The results indicate that the temporalis fascia is a better dural graft because of its intrinsic tissue properties.

  9. The transcription factor hepatocyte nuclear factor-6 controls the development of pancreatic ducts in the mouse.

    Science.gov (United States)

    Pierreux, Christophe E; Poll, Aurélie V; Kemp, Caroline R; Clotman, Frédéric; Maestro, Miguel A; Cordi, Sabine; Ferrer, Jorge; Leyns, Luc; Rousseau, Guy G; Lemaigre, Frédéric P

    2006-02-01

    A number of hereditary polycystic diseases are associated with formation of cysts within the pancreatic ducts. The cysts result from abnormal tubulogenesis, but how normal pancreatic duct development is controlled remains poorly understood. Here, we investigate the transcriptional mechanisms that control pancreatic duct development by addressing the role of the transcription factor hepatocyte nuclear factor (HNF)-6. Using immunostaining, we have determined the expression pattern of HNF-6 in pancreatic ducts during mouse development. Hnf6 null mice at various stages of development were studied by immunolocalization methods to assess the morphology, differentiation, and proliferation status of ductal cells. The expression of genes involved in hereditary polycystic diseases was determined by real-time, reverse-transcription polymerase chain reaction (RT-PCR). We show that HNF-6 is expressed in the pancreatic duct epithelium throughout development and that, in the absence of HNF-6, duct morphogenesis is perturbed. Although development of the intercalated ducts is normal, cysts appear within the interlobular and intralobular ducts. This is associated with abnormal development of primary cilia at the apical pole of the duct cells and with reduced expression of a set of genes involved in polycystic diseases, namely those coding for HNF-1beta and for the cilium-associated proteins polyductin/fibrocystin and cystin. We identify HNF-6 as the first transcriptional regulator of pancreatic duct development and reveal the existence of different regulatory mechanisms in distinct duct compartments. HNF-6 controls a network of genes involved in cilium formation and in hereditary polycystic diseases. Finally, HNF-6 deficiency represents a genetically defined model of pancreatic cystic disease.

  10. Reparación de la duramadre con poliesteruretano Repair of dura mater with polyesterurethane

    Directory of Open Access Journals (Sweden)

    K Barbosa

    2005-03-01

    were excluded. The clinical observations were made a day after surgery, at 15 and 90 days later to find signs of filtration of cerebrospinal fluid, wound infection and meningitis. Results: Neither filtration of the cerebrospinal fluid nor infection was found in any of the 30 patients (craniotomy 53.3 %, craniectomy 3.3 %, repair of depressed fractures of the cranium 20 %, repair of lumbar myelomeningocele 6.7 %, instrumentation and fusion of thoracolumbar spine 3.3 %, thoracic laminectomy 3.3 %, lumbar laminectomies 6.7 %, and lumbar discectomy 3.3 %. In a patient that was reoperated on (relapse due to cerebral metastasis, there were not observed adherences of the graft to the cortical surface. Conclusions: It seems that polyesterutherane is an appropriate dural substitute that can be easily manipulated (and in this case with no cost and that produces a hermetic closure of the dura mater without complications or adherences to the cortical surface. Key words: Duroplasty, dural substitute, polyesterurethane

  11. Nuclear war and nuclear peace

    Energy Technology Data Exchange (ETDEWEB)

    Segal, G.; Moreton, E.; Freedman, L.; Baylis, J.

    1983-01-01

    This book is an in-depth examination of East-West tactical and strategic nuclear weapons policy. The contributors explore such issues as the history and implications of tactical weapons in Europe, the general conflicts that have characterized US and Soviet interaction, the development of British nuclear weapons policy, and arms control including SALT I and II and the START talks.

  12. A Pilot Study Investigating the Effects of Advanced Nuclear Power Plant Control Room Technologies: Methods and Qualitative Results

    Energy Technology Data Exchange (ETDEWEB)

    BLanc, Katya Le [Idaho National Lab. (INL), Idaho Falls, ID (United States); Powers, David [Idaho National Lab. (INL), Idaho Falls, ID (United States); Joe, Jeffrey [Idaho National Lab. (INL), Idaho Falls, ID (United States); Spielman, Zachary [Idaho National Lab. (INL), Idaho Falls, ID (United States); Rice, Brandon [Idaho National Lab. (INL), Idaho Falls, ID (United States); Fitzgerald, Kirk [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2015-08-01

    Control room modernization is an important part of life extension for the existing light water reactor fleet. None of the 99 currently operating commercial nuclear power plants in the U.S. has completed a full-scale control room modernization to date. Nuclear power plant main control rooms for the existing commercial reactor fleet remain significantly analog, with only limited digital modernizations. Upgrades in the U.S. do not achieve the full potential of newer technologies that might otherwise enhance plant and operator performance. The goal of the control room upgrade benefits research is to identify previously overlooked benefits of modernization, identify candidate technologies that may facilitate such benefits, and demonstrate these technologies through human factors research. This report describes a pilot study to test upgrades to the Human Systems Simulation Laboratory at INL.

  13. Applications of Kalman Filtering to nuclear material control. [Kalman filtering and linear smoothing for detecting nuclear material losses

    Energy Technology Data Exchange (ETDEWEB)

    Pike, D.H.; Morrison, G.W.; Westley, G.W.

    1977-10-01

    The feasibility of using modern state estimation techniques (specifically Kalman Filtering and Linear Smoothing) to detect losses of material from material balance areas is evaluated. It is shown that state estimation techniques are not only feasible but in most situations are superior to existing methods of analysis. The various techniques compared include Kalman Filtering, linear smoothing, standard control charts, and average cumulative summation (CUSUM) charts. Analysis results indicated that the standard control chart is the least effective method for detecting regularly occurring losses. An improvement in the detection capability over the standard control chart can be realized by use of the CUSUM chart. Even more sensitivity in the ability to detect losses can be realized by use of the Kalman Filter and the linear smoother. It was found that the error-covariance matrix can be used to establish limits of error for state estimates. It is shown that state estimation techniques represent a feasible and desirable method of theft detection. The technique is usually more sensitive than the CUSUM chart in detecting losses. One kind of loss which is difficult to detect using state estimation techniques is a single isolated loss. State estimation procedures are predicated on dynamic models and are well-suited for detecting losses which occur regularly over several accounting periods. A single isolated loss does not conform to this basic assumption and is more difficult to detect.

  14. Quality control for the equipment of Nuclear medicine: experience of the H.U. de la Princesa; Control de calidad del equipamiento en Medicina Nuclear. Experiencia enel H.U. de la Princesa

    Energy Technology Data Exchange (ETDEWEB)

    Espana, M.L.; Gracia, A.; Prieto, C.; Lopez F, P. [Servicio de ProteccionRadiologica. Hospital Universitario de la Princesa C/ Diego de Leon 62, 28006Madrid (Spain)

    1998-12-31

    The quality control of the equipment used in a nuclear medicine service is a fundamental aspect in the Quality Assurance Program that in the present time is starting in our hospital. the objective of this work is to present the internal protocol used, its problematic associated with its starting, and the results obtained in the quality control as of the gamma camera as of the activimeter. In addition to the equipment own to the nuclear medicine service it has been used a Cs-137 source and puppets for several purposes. The results obtained demonstrated the stability of the controlled parameters which has led us to a restating of the established periodicities in our internal protocol, over all for some constancy tests. (Author)

  15. Enxertos homólogos de esclera e dura-máter em olhos de coelhos: análise histopatológica comparativa Homologous scleral and dura mater grafts in rabbit eyes

    Directory of Open Access Journals (Sweden)

    Davi Araf

    2007-12-01

    Full Text Available OBJETIVO: Avaliar a reação tecidual à implantação de enxertos homólogos de esclera e dura-máter. MÉTODOS: Foram realizadas cirurgias experimentais em 41 coelhos albinos da raça Nova Zelândia, sendo que dois coelhos foram selecionados, ao acaso, para serem doadores dos enxertos a serem utilizados no experimento. Trinta coelhos foram divididos em dois grupos: grupo D e grupo E, sendo submetidos à implantação dos tecidos homólogos e nove animais constituíram o grupo controle (grupo DE, submetidos à cirurgia sem enxertia. Os olhos foram enucleados e amostras foram colhidas em duas, seis e 12 semanas após o experimento, constituindo os subgrupos I, II e III. RESULTADOS: Foi realizada análise histopatológica qualitativa, além de estudo semiquantitativo comparativo da vascularização e infiltrado inflamatório na esclera e dura-máter transplantadas. Procedeu-se, também, a histomorfometria das medidas do lado dos enxertos com sistema analisador de imagens. Não houve diferença estatisticamente significante comparando-se a vascularização, infiltrado inflamatório e medidas do lado, entre os subgrupos I de esclera em relação à dura-máter, assim como nos subgrupos II. Não foram comparados os subgrupos III, pois foram observados somente fragmentos dos enxertos de dura-máter. CONCLUSÕES: O enxerto de dura-máter mostrou intensa reabsorção e progressiva substituição por tecido conjuntivo frouxo. O enxerto de esclera mostrou discreta reabsorção na periferia com formação de membrana fibrosa mais evidente, integrando este à esclera do hospedeiro.PURPOSE: To evaluate tissue reaction to implantation of homologous scleral and dura mater grafts. METHODS: Experimental surgeries were performed on 41 albine New Zealand rabbits; two rabbits were selected at random to be graft donors. Thirty rabbits were divided into two groups: group D and group E, receiving grafts of homologous tissues. The remaining nine animals comprised the

  16. DOE/DHS INDUSTRIAL CONTROL SYSTEM CYBER SECURITY PROGRAMS: A MODEL FOR USE IN NUCLEAR FACILITY SAFEGUARDS AND SECURITY

    Energy Technology Data Exchange (ETDEWEB)

    Robert S. Anderson; Mark Schanfein; Trond Bjornard; Paul Moskowitz

    2011-07-01

    Many critical infrastructure sectors have been investigating cyber security issues for several years especially with the help of two primary government programs. The U.S. Department of Energy (DOE) National SCADA Test Bed and the U.S. Department of Homeland Security (DHS) Control Systems Security Program have both implemented activities aimed at securing the industrial control systems that operate the North American electric grid along with several other critical infrastructure sectors (ICS). These programs have spent the last seven years working with industry including asset owners, educational institutions, standards and regulating bodies, and control system vendors. The programs common mission is to provide outreach, identification of cyber vulnerabilities to ICS and mitigation strategies to enhance security postures. The success of these programs indicates that a similar approach can be successfully translated into other sectors including nuclear operations, safeguards, and security. The industry regulating bodies have included cyber security requirements and in some cases, have incorporated sets of standards with penalties for non-compliance such as the North American Electric Reliability Corporation Critical Infrastructure Protection standards. These DOE and DHS programs that address security improvements by both suppliers and end users provide an excellent model for nuclear facility personnel concerned with safeguards and security cyber vulnerabilities and countermeasures. It is not a stretch to imagine complete surreptitious collapse of protection against the removal of nuclear material or even initiation of a criticality event as witnessed at Three Mile Island or Chernobyl in a nuclear ICS inadequately protected against the cyber threat.

  17. Applications of nuclear physics

    Science.gov (United States)

    Hayes, A. C.

    2017-02-01

    Today the applications of nuclear physics span a very broad range of topics and fields. This review discusses a number of aspects of these applications, including selected topics and concepts in nuclear reactor physics, nuclear fusion, nuclear non-proliferation, nuclear-geophysics, and nuclear medicine. The review begins with a historic summary of the early years in applied nuclear physics, with an emphasis on the huge developments that took place around the time of World War II, and that underlie the physics involved in designs of nuclear explosions, controlled nuclear energy, and nuclear fusion. The review then moves to focus on modern applications of these concepts, including the basic concepts and diagnostics developed for the forensics of nuclear explosions, the nuclear diagnostics at the National Ignition Facility, nuclear reactor safeguards, and the detection of nuclear material production and trafficking. The review also summarizes recent developments in nuclear geophysics and nuclear medicine. The nuclear geophysics areas discussed include geo-chronology, nuclear logging for industry, the Oklo reactor, and geo-neutrinos. The section on nuclear medicine summarizes the critical advances in nuclear imaging, including PET and SPECT imaging, targeted radionuclide therapy, and the nuclear physics of medical isotope production. Each subfield discussed requires a review article unto itself, which is not the intention of the current review; rather, the current review is intended for readers who wish to get a broad understanding of applied nuclear physics.

  18. Applications of nuclear physics.

    Science.gov (United States)

    Hayes, A C

    2017-02-01

    Today the applications of nuclear physics span a very broad range of topics and fields. This review discusses a number of aspects of these applications, including selected topics and concepts in nuclear reactor physics, nuclear fusion, nuclear non-proliferation, nuclear-geophysics, and nuclear medicine. The review begins with a historic summary of the early years in applied nuclear physics, with an emphasis on the huge developments that took place around the time of World War II, and that underlie the physics involved in designs of nuclear explosions, controlled nuclear energy, and nuclear fusion. The review then moves to focus on modern applications of these concepts, including the basic concepts and diagnostics developed for the forensics of nuclear explosions, the nuclear diagnostics at the National Ignition Facility, nuclear reactor safeguards, and the detection of nuclear material production and trafficking. The review also summarizes recent developments in nuclear geophysics and nuclear medicine. The nuclear geophysics areas discussed include geo-chronology, nuclear logging for industry, the Oklo reactor, and geo-neutrinos. The section on nuclear medicine summarizes the critical advances in nuclear imaging, including PET and SPECT imaging, targeted radionuclide therapy, and the nuclear physics of medical isotope production. Each subfield discussed requires a review article unto itself, which is not the intention of the current review; rather, the current review is intended for readers who wish to get a broad understanding of applied nuclear physics.

  19. MAP kinase-signaling controls nuclear translocation of tripeptidyl-peptidase II in response to DNA damage and oxidative stress

    Energy Technology Data Exchange (ETDEWEB)

    Preta, Giulio; Klark, Rainier de; Chakraborti, Shankhamala [Center for Molecular Medicine (CMM), Department of Medicine, Karolinska Institutet, Karolinska University Hospital, 171 76 Stockholm (Sweden); Glas, Rickard, E-mail: rickard.glas@ki.se [Center for Molecular Medicine (CMM), Department of Medicine, Karolinska Institutet, Karolinska University Hospital, 171 76 Stockholm (Sweden)

    2010-08-27

    Research highlights: {yields} Nuclear translocation of TPPII occurs in response to different DNA damage inducers. {yields} Nuclear accumulation of TPPII is linked to ROS and anti-oxidant enzyme levels. {yields} MAPKs control nuclear accumulation of TPPII. {yields} Inhibited nuclear accumulation of TPPII decreases DNA damage-induced {gamma}-H2AX expression. -- Abstract: Reactive oxygen species (ROS) are a continuous hazard in eukaroytic cells by their ability to cause damage to biomolecules, in particular to DNA. Previous data indicated that the cytosolic serine peptidase tripeptidyl-peptidase II (TPPII) translocates into the nucleus of most tumor cell lines in response to {gamma}-irradiation and ROS production; an event that promoted p53 expression as well as caspase-activation. We here observed that nuclear translocation of TPPII was dependent on signaling by MAP kinases, including p38MAPK. Further, this was caused by several types of DNA-damaging drugs, a DNA cross-linker (cisplatinum), an inhibitor of topoisomerase II (etoposide), and to some extent also by nucleoside-analogues (5-fluorouracil, hydroxyurea). In the minority of tumor cell lines where TPPII was not translocated into the nucleus in response to DNA damage we observed reduced intracellular ROS levels, and the expression levels of redox defense systems were increased. Further, treatment with the ROS-inducer {gamma}-hexa-chloro-cyclohexane ({gamma}-HCH, lindane), an inhibitor of GAP junctions, restored nuclear translocation of TPPII in these cell lines upon {gamma}-irradiation. Moreover, blocking nuclear translocation of TPPII in etoposide-treated cells, by using a peptide-derived inhibitor (Z-Gly-Leu-Ala-OH), attenuated expression of {gamma}-H2AX in {gamma}-irradiated melanoma cells. Our results indicated a role for TPPII in MAPK-dependent DNA damage signaling.

  20. The Fun30 chromatin remodeler Fft3 controls nuclear organization and chromatin structure of insulators and subtelomeres in fission yeast.

    Directory of Open Access Journals (Sweden)

    Babett Steglich

    2015-03-01

    Full Text Available In eukaryotic cells, local chromatin structure and chromatin organization in the nucleus both influence transcriptional regulation. At the local level, the Fun30 chromatin remodeler Fft3 is essential for maintaining proper chromatin structure at centromeres and subtelomeres in fission yeast. Using genome-wide mapping and live cell imaging, we show that this role is linked to controlling nuclear organization of its targets. In fft3∆ cells, subtelomeres lose their association with the LEM domain protein Man1 at the nuclear periphery and move to the interior of the nucleus. Furthermore, genes in these domains are upregulated and active chromatin marks increase. Fft3 is also enriched at retrotransposon-derived long terminal repeat (LTR elements and at tRNA genes. In cells lacking Fft3, these sites lose their peripheral positioning and show reduced nucleosome occupancy. We propose that Fft3 has a global role in mediating association between specific chromatin domains and the nuclear envelope.

  1. Nuclear medicine incident reporting in Australia: control charts and notification rates inform quality improvement.

    Science.gov (United States)

    Larcos, G; Collins, L T; Georgiou, A; Westbrook, J I

    2015-06-01

    Australia has a statutory incident reporting system for radiopharmaceutical maladministrations, but additional research into registry data is required for the purpose of quality improvement in nuclear medicine. We (i) used control charts to identify factors contributing to special cause variation (indicating higher than expected rates) in maladministrations and (ii) evaluated the impact of heterogeneous notification criteria and extent of underreporting among jurisdictions and individual facilities, respectively. Anonymised summaries of Australian Radiation Incident Register reports permitted calculation of national monthly maladministration notification rates for 2007-2012 and preparation of control charts. Multivariate logistic regression assessed the association of population, insurance and regulatory characteristics with maladministration notifications in each Australian State and Territory. Maladministration notification rates from two facilities with familiarity of notification processes and commitment to radiation protection were compared with those elsewhere. Special cause variation occurred in only 3 months, but contributed to 21% of all incidents (42 of 197 patients), mainly because of 'clusters' of maladministrations (n = 24) arising from errors in bulk radiopharmaceutical dispensing. Maladministration notification rates varied significantly between jurisdictions (0 to 12.2 maladministrations per 100 000 procedures (P < 0.05)) and individual facilities (31.7 vs 5.8 per 100 000; χ(2) = 40; 1 degree of freedom, P < 0.001). Unexpected increases in maladministration notifications predominantly relate to incident 'clusters' affecting multiple patients. The bulk preparation of radiopharmaceuticals is a vulnerable process and merits additional safeguards. Maladministration notification rates in Australia are heterogeneous. Adopting uniform maladministration notification criteria among States and Territories and methods to overcome underreporting are

  2. Estructura y agencia en la migración infantil centroamericana

    OpenAIRE

    Acuña González, Guillermo E.

    2016-01-01

    Al promediar el año 2014 se activaron voces que alertaban sobre la presencia de decenas de miles de niños y niñas migrantes centroamericanos tratando de cruzar la frontera entre México y Estados Unidos. Las respuestas elaboradas por las autoridades migratorias y estatales de ambos países privilegiaron un esquema de seguridad y control, sin atender las especificidades de esta migración. Los discursos públicos homogeneizaron las miradas sobre quienes hacían parte de estos procesos migratorios e...

  3. La Elección Estratégica y el Enfoque de la Teoría de Agencia – Un Ensayo Teórico

    Directory of Open Access Journals (Sweden)

    Rosalia Barbosa Lavarda

    2011-09-01

    Full Text Available definición de los factores, se puede decir que la concepción y visión directiva, con el enfoque de la lógica dominante y de la strategic choice elige, con su estrategia, el entorno o el mercado en el cual la empresa actuará. Por su vez el condicionamiento contingente influye en los productos o servicios que la empresa obtendrá, lo cual condiciona los tipos de trabajo y el sistema técnico o tecnología que la empresa utilizará, que a su vez, conduce las formas y necesidades organizativas. El entendimiento es que hay un marco conceptual en torno de la concepción y visión directiva, el condicionamiento contingente, los tipos de trabajo y el enfoque de la teoría de agencia. Ese pensamiento va se estableciendo en lo largo del trabajo a con el fin de contestar la siguiente cuestión de investigación: ¿Cómo y a través de que variables la organización puede minimizar los problemas de agencia y mejorar la gestión del trabajo? Cuanto a la forma de desarrollo del estudio ese se caracteriza como un ensayo teórico (Whetten, 2003, una vez que revisó conceptos y teorías en trabajos,seminales de manera a encontrar la adecuada gestión (fit de las variables de diseño para posibilitar la propuesta de una mejor gestión de los diferentes tipos de trabajo, minimizando los problemas de agencia, principalmente para organizaciones que se dan cuenta que el entorno siempre influye o condiciona los productos y servicios de la empresa, previamente concebidos por la elección estratégica.

  4. ‘Una ventanita’: Vida cotidiana de las dueñas de casa y agencia de las máquinas tragamonedas en Chile

    Directory of Open Access Journals (Sweden)

    Francisco Olivos Ravé

    2012-07-01

    Full Text Available Este artículo intenta dar respuesta de forma etnográfica a la pregunta de cuál es el sentido que ocupan las máquinas tragamonedas y la agencia que estas tienen sobre la vida cotidiana de las dueñas de casa de un barrio de clase media baja en la comuna de San Bernardo, Santiago. Se descubre que el juego en las máquinas tragamonedas no constituye un momento extraordinario, sino que es parte de la rutina, pero a la vez permite una ruptura de la simultaneidad del tiempo libre con el de las labores del hogar que caracteriza a otras actividades como ver televisión. Sin embargo, gracias al enfoque de la teoría del actor red es posible observar que la agencia de las máquinas tragamonedas canaliza el escape de lo que significa la casa, es decir, de las responsabilidades y de los problemas familiares. Se genera, por otra parte, un encuentro de las dueñas de casa con su self. Asimismo, la agencia de las máquinas tragamonedas desencadena controversias en la familia volviéndola parte de la red que se forma en torno el juego. Finalmente, se plantea que las decisiones que se tomen en torno a la legislación sobre el juego deben tener en cuenta una traducción que permita comprender la lógica del juego en la vida cotidiana de las dueñas de casa y de los jugadores en general.

  5. Interactive Virtual Reactor and Control Room for Education and Training at Universities and Nuclear Power Plants

    Energy Technology Data Exchange (ETDEWEB)

    Satoh, Yoshinori; Li, Ye; Zhu, Xuefeng; Rizwan, Uddin [University of Illinois, Urbana (United States)

    2014-08-15

    Efficient and effective education and training of nuclear engineering students and nuclear workers are critical for the safe operation and maintenance of nuclear power plants. With an eye toward this need, we have focused on the development of 3D models of virtual labs for education, training as well as to conduct virtual experiments. These virtual labs, that are expected to supplement currently available resources, and have the potential to reduce the cost of education and training, are most easily developed on game-engine platforms. We report some recent extensions to the virtual model of the University of Illinois TRIGA reactor.

  6. Heat Transfer Salts for Nuclear Reactor Systems - Chemistry Control, Corrosion Mitigation, and Modeling

    Energy Technology Data Exchange (ETDEWEB)

    Anderson, Mark [Univ. of Wisconsin, Madison, WI (United States); Sridharan, Kumar [Univ. of Wisconsin, Madison, WI (United States); Morgan, Dane [Univ. of Wisconsin, Madison, WI (United States); Peterson, Per [Univ. of Wisconsin, Madison, WI (United States); Calderoni, Pattrick [Univ. of Wisconsin, Madison, WI (United States); Scheele, Randall [Univ. of Wisconsin, Madison, WI (United States); Casekka, Andrew [Univ. of Wisconsin, Madison, WI (United States); McNamara, Bruce [Univ. of Wisconsin, Madison, WI (United States)

    2015-01-22

    The concept of a molten salt reactor has existed for nearly sixty years. Previously all work was done during a large collaborative effort at Oak Ridge National Laboratory, culminating in a research reactor which operated for 15,000 hours without major error. This technical success has garnished interest in modern, high temperature, reactor schemes. Research using molten fluoride salts for nuclear applications requires a steady supply of high grade molten salts. There is no bulk supplier of research grade fluoride salts in the world, so a facility which could provide all the salt needed for testing at the University of Wisconsin had to be produced. Two salt purification devices were made for this purpose, a large scale purifier, and a small scale purifier, each designed to clean the salts from impurities and reduce their corrosion potential. As of now, the small scale has performed with flibe salt, hydrogen, and hydrogen fluoride, yielding clean salt. This salt is currently being used in corrosion testing facilities at the Massachusetts Institute of Technology and the University of Wisconsin. Working with the beryllium based salts requires extensive safety measures and health monitoring to prevent the development of acute or chronic beryllium disease, two pulmonary diseases created by an allergic reaction to beryllium in the lungs. Extensive health monitoring, engineering controls, and environment monitoring had to be set up with the University of Wisconsin department of Environment, Health and Safety. The hydrogen fluoride required for purification was also an extreme health hazard requiring thoughtful planning and execution. These dangers have made research a slow and tedious process. Simple processes, such as chemical handling and clean-up, can take large amounts of ingenuity and time. Other work has complemented the experimental research at Wisconsin to advance high temperature reactor goals. Modeling work has been performed in house to re

  7. Evaluación de los contenidos de información de medicamentos en un grupo de agencias reguladoras de medicamentos

    OpenAIRE

    Gil Rojas, Yaneth

    2016-01-01

    OBJETIVO: Evaluar las diferencias de información publicada por el Invima y otras Autoridades Reguladoras de Medicamentos en relación a un grupo de variables seleccionadas y analizar las diferencias aplicando estrategias de visualización de datos. METODOLOGÍA: Estudio descriptivo de corte transversal, en el cual se comparan las diferencias en la información de medicamentos publicada en las agencias reguladoras de medicamentos. Para la definición de los criterios de comparación, más relevantes ...

  8. Propuesta de análisis de puestos de trabajo para la Agencia de Servicios de Electricidad de Esparza, del Instituto Costarricense de Electricidad

    OpenAIRE

    Chaves Chaves, Henry

    2007-01-01

    Tesis de maestría -- Universidad de Costa Rica. Posgrado en Administración y Dirección de Empresas. Maestría Profesional en Administración y Dirección de Empresas, 2007 Chaves Chaves, Henry Evaluar el Análisis de puestos de trabajo aplicado en la actualidad en la Agencia de Servicios Eléctricos de Esparza, para plantear una propuesta de soluciones a los problemas que se identifiquen. Trabajo final de graduación. Programa de Posgrado en Administración y en Dirección de Empresas. –San José, ...

  9. Análisis de los expedientes sobre medicamentos genéricos incoados ante la Agencia Española del Medicamento periodo 2000-2002

    OpenAIRE

    Santos Real, Heidi de los

    2005-01-01

    Los medicamentos requieren una autorización para ser comercializados. La finalidad de la autorización es evitar el uso no controlado de estos productos, que pueden ser nocivos y suponer un riesgo para la salud pública. Para obtener la autorización de comercialización de un medicamento por parte de la Agencia Española del Medicamento, deben seguirse determinados procedimientos de registro que garantizan la concesión de las autorizaciones tras el cumplimiento de estrictos criterios de calidad, ...

  10. UNIVERSITY TEACHING-LEARNING PROCESS: REFLECTIONS THROUGHOUT THE AGENCY THEORY EL PROCESO DE ENSEÑANZA-APRENDIZAJE UNIVERSITARIO: REFLEXIONES A TRAVÉS DE LA TEORÍA DE AGENCIA

    Directory of Open Access Journals (Sweden)

    Víctor Jacques Parraguez

    2011-03-01

    Full Text Available This work analyses some reasons that might explain the insufficient academic level which is perceived in universities of developing countries. The discussion element is the teacher-student relationship which is studied under the perspective of the agency theory. It is concluded that in absence of efficient monitoring mechanisms of the teacher and student’s behavior might proliferate gaps of due diligence which attempts against the quality of the teaching-learning process.En este trabajo se analizan algunas razones que pueden explicar el insuficiente nivel académico que se percibe en universidades de países en vías de desarrollo. El elemento de discusión es la relación profesor-alumno que es estudiada bajo el prisma de la teoría de agencia. Se concluye que en ausencia de eficientes mecanismos de control de la conducta tanto del profesor como del estudiante pueden proliferar vicios de responsabilidad que atentan contra la calidad del proceso de enseñanza-aprendizaje.

  11. Supporting the President's Arms Control and Nonproliferation Agenda: Transparency and Verification for Nuclear Arms Reductions

    Energy Technology Data Exchange (ETDEWEB)

    Doyle, James E [Los Alamos National Laboratory; Meek, Elizabeth [Los Alamos National Laboratory

    2009-01-01

    The President's arms control and nonproliferation agenda is still evolving and the details of initiatives supporting it remain undefined. This means that DOE, NNSA, NA-20, NA-24 and the national laboratories can help define the agenda, and the policies and the initiatives to support it. This will require effective internal and interagency coordination. The arms control and nonproliferation agenda is broad and includes the path-breaking goal of creating conditions for the elimination of nuclear weapons. Responsibility for various elements of the agenda will be widely scattered across the interagency. Therefore an interagency mapping exercise should be performed to identify the key points of engagement within NNSA and other agencies for creating effective policy coordination mechanisms. These can include informal networks, working groups, coordinating committees, interagency task forces, etc. It will be important for NA-20 and NA-24 to get a seat at the table and a functional role in many of these coordinating bodies. The arms control and nonproliferation agenda comprises both mature and developing policy initiatives. The more mature elements such as CTBT ratification and a follow-on strategic nuclear arms treaty with Russia have defined milestones. However, recent press reports indicate that even the START follow-on strategic arms pact that is planned to be complete by the end of 2009 may take significantly longer and be more expansive in scope. The Russians called for proposals to count non-deployed as well as deployed warheads. Other elements of the agenda such as FMCT, future bilateral nuclear arms reductions following a START follow-on treaty, nuclear posture changes, preparations for an international nuclear security summit, strengthened international safeguards and multilateral verification are in much earlier stages of development. For this reason any survey of arms control capabilities within the USG should be structured to address potential needs

  12. Survey and analysis on environmental and electromagnetic effect on instrumentation and control equipment of nuclear power plants

    Energy Technology Data Exchange (ETDEWEB)

    Hwang, In Koo; Lee, Dong Young; Cha, Kyung Ho

    2001-03-01

    As the instrumentation and control (I and C) equipment suppliers tend to provide digital components rather than conventional analog type components for instrumentation and control systems of nuclear power plants(NPPs), it is unavoidable to adopt digital equipment for safety I and C systems as well as non-safety systems. However, the full introduction of digital equipment for I and C systems of nuclear power plants raises several concerns which have not been considered in conventional analog I and C equipment. The two major examples of the issues of digital systems are environmental/electromagnetic compatibility (EMC) and software reliability. This report presents the survey and research results on environmental and electromagnetic effect on I and C equipment of nuclear power plants to give a guideline for aging management and design process. Electromagnetic site surveys were conducted to be used as a part of technical basis to demonstrate that I and C systems are compatible with the ambient electromagnetic noise in Korean nuclear power plants.

  13. Poderes y Agencia: el resto es literatura / Proxy and Agency: the Rest is Literature

    Directory of Open Access Journals (Sweden)

    Katheen McNerney

    2011-01-01

    Full Text Available Resumen: De entre la gran multitud de emigrantes catalano-parlantes que llegó a la Cuba colonial, un cierto número de mujeres llegó a La Habana en busca de sus esposos, aquellos con los que se habían casado “por poderes” (poders justo antes de realizar el largo viaje. La obra de Carmen Riera Cap al cel obert narra la historia de las hermanas Fortesa, enviadas desde Mallorca. A Isabel la eligió su padre para casarla con un primo rico y se envió a María para acompañarla. Solamente María sobrevive el terrible viaje, que tiene lugar durante la última fase del control español sobre Cuba. Una vez en Cuba y recuperada de los avatares del viaje, María considera la vida monástica, pero en vez de ello, en su primera decisión real, acepta la oferta de matrimonio de Josep Fortalesa.El sistema de poderes continuó aun tras la independencia de Cuba del control de España en 1898 y esta forma de matrimonio conforma el tema de L’herència de Cuba de Margarida Aritzeta, en cuya portada se describe como “absolutament verídica”. Eugènia se casa con Basilio, un vecino de su pequeño pueblo aragonés cuando él, por medio de una carta y billete a la isla, manda que la traigan una vez instalado él allí después del viaje de 1925. Las dos novelas forman, de manera conjunta y a grandes rasgos, unos cien años de historia cubana, desde finales del siglo diecinueve hasta finales del siglo veinte, poniendo de relieve la lucha de mujeres que a menudo parecen arrastradas como hojas secas en un huracán, como diría Gertrudis Gómez de Avellaneda.

  14. Cosmic radiation increases the risk of nuclear cataract in airline pilots: a population-based case-control study.

    Science.gov (United States)

    Rafnsson, Vilhjalmur; Olafsdottir, Eydis; Hrafnkelsson, Jon; Sasaki, Hiroshi; Arnarsson, Arsaell; Jonasson, Fridbert

    2005-08-01

    Aviation involves exposure to ionizing radiation of cosmic origin. The association between lesions of the ocular lens and ionizing radiation is well-known. To investigate whether employment as a commercial airline pilot and the resulting exposure to cosmic radiation is associated with lens opacification. This is a population-based case-control study of 445 men. Lens opacification was classified into 4 types using the World Health Organization simplified grading system. These 4 types, serving as cases, included 71 persons with nuclear cataracts, 102 with cortical lens opacification, 69 with central optical zone involvement, and 32 with posterior subcapsular lens opacification. Control subjects are those with a different type of lens opacification or without lens opacification. Exposure was assessed based on employment time as pilots, annual number of hours flown on each aircraft type, time tables, flight profiles, and individual cumulative radiation doses (in millisieverts) calculated by a software program. Odds ratios were calculated using logistic regression. The odds ratio for nuclear cataract risk among cases and controls was 3.02 (95% confidence interval, 1.44-6.35) for pilots compared with nonpilots, adjusted for age, smoking status, and sunbathing habits. The odds ratio for nuclear cataract associated with estimation of cumulative radiation dose (in millisieverts) to the age of 40 years was 1.06 (95% confidence interval, 1.02-1.10), adjusted for age, smoking status, and sunbathing habits. The association between the cosmic radiation exposure of pilots and the risk of nuclear cataracts, adjusted for age, smoking status, and sunbathing habits, indicates that cosmic radiation may be a causative factor in nuclear cataracts among commercial airline pilots.

  15. Calculation of neutron activation of control rods of a nuclear reactor, using MCNP5; Calculo de activacion neutronica de barras de control de un reactor nuclear, utilizando MCNP5

    Energy Technology Data Exchange (ETDEWEB)

    Pena V, J.D.

    2016-07-01

    The control rods of a nuclear reactor are activated by neutron irradiation. The generated activity produces a dose around the rod which is irrelevant inside the reactor, but significant when the rod is withdrawn and placed in a storage pool, because this dose is a potential risk to the surrounding personnel. On the other hand, most of the activation occurs in the stainless steel components of the rod. The Monte Carlo model can reliably determine the activation produced in a stainless steel part exposed to a neutron flux in a reactor and the dose measurement around this part. This thesis presents the Monte Carlo models developed for the activation of the control rods of the TRIGA Mark III reactor of Instituto Nacional de Investigaciones Nucleares (ININ) when only standard fuel was available. Therefore, the validations of the Monte Carlo models are reliable. (Author)

  16. Nuclear track microfilters in controlled drug delivery against chronic skin disease

    Energy Technology Data Exchange (ETDEWEB)

    Gopalani, D. E-mail: deflab@sancharnet.in; Jodha, A.S.; Saravanan, S.; Kumar, S

    2003-06-01

    Nuclear track microfilters have been developed for transdermal therapeutic system. The transdermal therapeutic method reduces the toxicity of the drug as compared to other conventional methods. For this purpose a slow drug release system containing the nuclear track microfilter was developed. This device was applied to the patients suffering from psoriasis and cellulites diseases. The delivery of the drug to the patient was confirmed through high performance liquid chromatography. The preliminary results have shown that patients are responding to drugs with minimum toxicity.

  17. Under control. An archeology of nuclear power; Unter Kontrolle. Eine Archaeologie der Atomkraft

    Energy Technology Data Exchange (ETDEWEB)

    Sattel, Volker; Stefanescu, Stefan

    2013-07-01

    The volume includes a variety of photographs from different German research and power reactors, simulators, the infrastructure of power plants, working situations in the power plant, including fuel exchange and inspection procedures, the dismantling of decommissioned power nuclear facilities and radioactive waste storage facilities. The second part includes interviews with scientists concerning radiobiology, nuclear waste storage, fuel reprocessing, reactor physics, reactor operation, training in the simulator and risk research.

  18. Role of nuclear grade graphite in controlling oxidation in modular HTGRs

    Energy Technology Data Exchange (ETDEWEB)

    Windes, Willaim [Idaho National Lab. (INL), Idaho Falls, ID (United States); Strydom, G. [Idaho National Lab. (INL), Idaho Falls, ID (United States); Kane, J. [Idaho National Lab. (INL), Idaho Falls, ID (United States); Smith, R. [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2014-11-01

    The passively safe High Temperature Gas-cooled Reactor (HTGR) design is one of the primary concepts considered for Generation IV and Small Modular Reactor (SMR) programs. The helium cooled, nuclear grade graphite moderated core achieves extremely high operating temperatures allowing either industrial process heat or electricity generation at high efficiencies. In addition to their neutron moderating properties, nuclear grade graphite core components provide excellent high temperature stability, thermal conductivity, and chemical compatibility with the high temperature nuclear fuel form. Graphite has been continuously used in nuclear reactors since the 1940’s and has performed remarkably well over a wide range of core environments and operating conditions. Graphite moderated, gas-cooled reactor designs have been safely used for research and power production purposes in multiple countries since the inception of nuclear energy development. However, graphite is a carbonaceous material, and this has generated a persistent concern that the graphite components could actually burn during either normal or accident conditions [ , ]. The common assumption is that graphite, since it is ostensibly similar to charcoal and coal, will burn in a similar manner. While charcoal and coal may have the appearance of graphite, the internal microstructure and impurities within these carbonaceous materials are very different. Volatile species and trapped moisture provide a source of oxygen within coal and charcoal allowing them to burn. The fabrication process used to produce nuclear grade graphite eliminates these oxidation enhancing impurities, creating a dense, highly ordered form of carbon possessing high thermal diffusivity and strongly (covalently) bonded atoms.

  19. Efficient planning and cost control in the demolition of nuclear facilities; Effiziente Planung und Kostenueberwachung beim Rueckbau Kerntechnischer Anlagen

    Energy Technology Data Exchange (ETDEWEB)

    Auler, I.; Petrasch, P. [NUKEM GmbH, Bereich NIS Ingenieure, Alzenau (Germany)

    2006-10-15

    Demolishing a nuclear facility is not only a technical challenge but also implies demanding measures of planning and project control, especially cost control. Major reasons and the requirements they entail are covered in the article. The long period of time required for demolition projects, and a number of specific criteria to be met, are major challenges facing planning, management, and control. The most important controlled variables are deadlines, manpower, equipment, and cost. For a project to succeed, planning therefore must closely interact with execution. Project planning and control systems must be structured clearly, flexible, and able to handle and document procedures, plant data, and costs in an interconnected fashion. They must incorporate both work flow and database functions. NIS Ingenieure developed the CORA and CALCOM project planning and control system specifically for planning and control of the decommissioning and disposal of nuclear facilities. The system is operated in close exchange of data with proven project management systems, such as MS PROJECT or PRIMAVERA. The system has proved its merits for many years in concept development, benchmark exercises, sensitivity analyses, and comparisons of targets versus performance in project planning and control. (orig.)

  20. Hepatocyte Nuclear Factor 4α Controls Iron Metabolism and Regulates Transferrin Receptor 2 in Mouse Liver*

    Science.gov (United States)

    Matsuo, Shunsuke; Ogawa, Masayuki; Muckenthaler, Martina U.; Mizui, Yumiko; Sasaki, Shota; Fujimura, Takafumi; Takizawa, Masayuki; Ariga, Nagayuki; Ozaki, Hiroaki; Sakaguchi, Masakiyo; Gonzalez, Frank J.; Inoue, Yusuke

    2015-01-01

    Iron is an essential element in biological systems, but excess iron promotes the formation of reactive oxygen species, resulting in cellular toxicity. Several iron-related genes are highly expressed in the liver, a tissue in which hepatocyte nuclear factor 4α (HNF4α) plays a critical role in controlling gene expression. Therefore, the role of hepatic HNF4α in iron homeostasis was examined using liver-specific HNF4α-null mice (Hnf4aΔH mice). Hnf4aΔH mice exhibit hypoferremia and a significant change in hepatic gene expression. Notably, the expression of transferrin receptor 2 (Tfr2) mRNA was markedly decreased in Hnf4aΔH mice. Promoter analysis of the Tfr2 gene showed that the basal promoter was located at a GC-rich region upstream of the transcription start site, a region that can be transactivated in an HNF4α-independent manner. HNF4α-dependent expression of Tfr2 was mediated by a proximal promoter containing two HNF4α-binding sites located between the transcription start site and the translation start site. Both the GC-rich region of the basal promoter and the HNF4α-binding sites were required for maximal transactivation. Moreover, siRNA knockdown of HNF4α suppressed TFR2 expression in human HCC cells. These results suggest that Tfr2 is a novel target gene for HNF4α, and hepatic HNF4α plays a critical role in iron homeostasis. PMID:26527688

  1. Hepatocyte Nuclear Factor 4α Controls Iron Metabolism and Regulates Transferrin Receptor 2 in Mouse Liver.

    Science.gov (United States)

    Matsuo, Shunsuke; Ogawa, Masayuki; Muckenthaler, Martina U; Mizui, Yumiko; Sasaki, Shota; Fujimura, Takafumi; Takizawa, Masayuki; Ariga, Nagayuki; Ozaki, Hiroaki; Sakaguchi, Masakiyo; Gonzalez, Frank J; Inoue, Yusuke

    2015-12-25

    Iron is an essential element in biological systems, but excess iron promotes the formation of reactive oxygen species, resulting in cellular toxicity. Several iron-related genes are highly expressed in the liver, a tissue in which hepatocyte nuclear factor 4α (HNF4α) plays a critical role in controlling gene expression. Therefore, the role of hepatic HNF4α in iron homeostasis was examined using liver-specific HNF4α-null mice (Hnf4a(ΔH) mice). Hnf4a(ΔH) mice exhibit hypoferremia and a significant change in hepatic gene expression. Notably, the expression of transferrin receptor 2 (Tfr2) mRNA was markedly decreased in Hnf4a(ΔH) mice. Promoter analysis of the Tfr2 gene showed that the basal promoter was located at a GC-rich region upstream of the transcription start site, a region that can be transactivated in an HNF4α-independent manner. HNF4α-dependent expression of Tfr2 was mediated by a proximal promoter containing two HNF4α-binding sites located between the transcription start site and the translation start site. Both the GC-rich region of the basal promoter and the HNF4α-binding sites were required for maximal transactivation. Moreover, siRNA knockdown of HNF4α suppressed TFR2 expression in human HCC cells. These results suggest that Tfr2 is a novel target gene for HNF4α, and hepatic HNF4α plays a critical role in iron homeostasis. © 2015 by The American Society for Biochemistry and Molecular Biology, Inc.

  2. Development of advanced automatic control system for nuclear ship. 2. Perfect automatic operation after reactor scram events

    Energy Technology Data Exchange (ETDEWEB)

    Yabuuchi, Noriaki; Nakazawa, Toshio; Takahashi, Hiroki; Shimazaki, Junya; Hoshi, Tsutao [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    1997-11-01

    An automatic operation system has been developed for the purpose of realizing a perfect automatic plant operation after reactor scram events. The goal of the automatic operation after a reactor scram event is to bring the reactor hot stand-by condition automatically. The basic functions of this system are as follows; to monitor actions of the equipments of safety actions after a reactor scram, to control necessary control equipments to bring a reactor to a hot stand-by condition automatically, and to energize a decay heat removal system. The performance evaluation on this system was carried out by comparing the results using to Nuclear Ship Engineering Simulation System (NESSY) and the those measured in the scram test of the nuclear ship `Mutsu`. As the result, it was showed that this system had the sufficient performance to bring a reactor to a hot syand-by condition quickly and safety. (author)

  3. Virtual control desk for operators training: a case study for a nuclear power plant simulator; Mesa de controle virtual para treinamento de operadores: um estudo de caso para um simulador de usina nuclear

    Energy Technology Data Exchange (ETDEWEB)

    Aghina, Mauricio Alves da Cunha e

    2009-03-15

    Nuclear Power Plant (NPP) is a facility for electrical energy generation. Because of its high degree of complexity and very rigid norms of security it is extremely necessary that operators are very well trained for the NPP operation. A mistaken operation by a human operator may cause a shutdown of the NPP, incurring in a huge economical damage for the owner and for the population in the case of a electric net black out. To reduce the possibility of a mistaken operation, the NPP usually have a full scope simulator of the plant's control room, which is the physical copy of the original control room. The control of this simulator is a computer program that can generate the equal functioning of the normal one or some scenarios of accidents to train the operators in many abnormal conditions of the plant. A physical copy of the control room has a high cost for its construction, not only of its facilities but also for its physical components. The proposal of this work is to present a project of a virtual simulator with the modeling in 3D stereo of a control room of a given nuclear plant with the same operation functions of the original simulator. This virtual simulator will have a lower cost and serves for pretraining of operators with the intention of making them familiar to the original control room. (author)

  4. Topical dura mater application of CFA induces enhanced expression of c-fos and glutamate in rat trigeminal nucleus caudalis

    DEFF Research Database (Denmark)

    Lukács, M; Warfvinge, K; Tajti, J

    2017-01-01

    BACKGROUND: Migraine is a debilitating neurological disorder where trigeminovascular activation plays a key role. We have previously reported that local application of Complete Freund's Adjuvant (CFA) onto the dura mater caused activation in rat trigeminal ganglion (TG) which was abolished......) was achieved by application of CFA onto the dural parietal surface. SZR72 was given intraperitoneally (i.p.), one dose prior CFA deposition and repeatedly daily for 7 days. Immunohistochemical studies were performed for mapping glutamate, c-fos, PACAP, substance P, IL-6, IL-1β and TNFα in the TNC/Sp5 and other...... regions of the brainstem and at the C1-C2 regions of the spinal cord. RESULTS: We found that CFA increased c-fos and glutamate immunoreactivity in TNC and C1-C2 neurons. This effect was mitigated by SZR72. PACAP positive fibers were detected in the fasciculus cuneatus and gracilis. Substance P, TNFα, IL-6...

  5. Nuclear safety

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2014-07-01

    The Program on Nuclear Safety comprehends Radioprotection, Radioactive Waste Management and Nuclear Material Control. These activities are developed at the Nuclear Safety Directory. The Radioactive Waste Management Department (GRR) was formally created in 1983, to promote research and development, teaching and service activities in the field of radioactive waste. Its mission is to develop and employ technologies to manage safely the radioactive wastes generated at IPEN and at its customer’s facilities all over the country, in order to protect the health and the environment of today's and future generations. The Radioprotection Service (GRP) aims primarily to establish requirements for the protection of people, as workers, contractors, students, members of the general public and the environment from harmful effects of ionizing radiation. Furthermore, it also aims to establish the primary criteria for the safety of radiation sources at IPEN and planning and preparing for response to nuclear and radiological emergencies. The procedures about the management and the control of exposures to ionizing radiation are in compliance with national standards and international recommendations. Research related to the main activities is also performed. The Nuclear Material Control has been performed by the Safeguard Service team, which manages the accountability and the control of nuclear material at IPEN facilities and provides information related to these activities to ABACC and IAEA. (author)

  6. Las relaciones públicas ante el reto digital y el fenómeno Twiter: estudio sobre la respuesta de las agencias de RRPP y del subsector empresarial de las bebidas fermentadas en España

    OpenAIRE

    Fernández Muñoz, Cristóbal

    2012-01-01

    El principal objetivo marcado en este trabajo de investigación es el de profundizar en el conocimiento del impacto que la comunicación digital está teniendo entre los practicantes de las Relaciones Públicas en España en el ámbito de las agencias de servicios profesionales y de un subsector empresarial español, en este caso el de las bebidas fermentas, como muestra del universo corporativo en nuestro país. Las agencias de RR.PP. y los departamentos de comunicación de las organizaciones del sec...

  7. Influencia de la cultura financiera en los niveles de productividad de los Técnicos operativos de Créditos del Banco de la Nación - Agencia Arequipa: 2012 - 2014

    OpenAIRE

    Sánchez Advíncula, Jaime Fredy

    2016-01-01

    La presente investigación tiene como objetivo analizar la influencia de la cultura financiera de los clientes que atiende el Banco de la Nación – Agencia Arequipa, en los niveles de productividad de los Técnicos Operativos de Créditos. La hipótesis de investigación fue verificada, ya que la cultura financiera de los clientes del Banco de la Nación – Agencia Arequipa, influye en los niveles de productividad de los Técnicos Operativos de Créditos. Se trata de una investigación...

  8. Automated system of control of radioactive liquid effluents of patients submitted to therapy in hospitals of nuclear medicine (SACEL); Sistema automatizado de control de efluentes liquidos radiactivos de pacientes sometidos a terapia en hospitales de medicina nuclear (SACEL)

    Energy Technology Data Exchange (ETDEWEB)

    Ruiz C, M.A.; Rivero G, T.; Celis del Angel, L.; Sainz M, E.; Molina, G. [ININ, 52045 Ocoyoacac, Estado de Mexico (Mexico)]. e-mail: marc@nuclear.inin.mx

    2006-07-01

    Different hospitals of nuclear medicine require of the technical attendance for the design, construction and instrumentation of an effluents retention system coming from the room dedicated to the medical application of iodine 131, with the one object of giving execution to the normative requirements of radiological protection, settled down in the General Regulation of Radiological Safety (RGSR) emitted by the CNSNS in November, 1988 and in the corresponding official standards. An automatic system of flow measurement, the activity concentration of the effluents to the drainage, the discharges control and the automated report it will allow the execution of the national regulations, also the elimination of unhealthy activities as the taking of samples, analysis of those same and the corresponding paperwork, its will allow that the SACEL is capable of to carry out registrations that are to consult in an automated way. The changes in the demands of the National Commission of Nuclear Safety and Safeguards in relation to the liberation of radioactive material in hospitals by medical treatments, it has created the necessity to develop a system that quantifies and dose the liquid effluents of people under thyroid treatment with iodine-131 to the drainage. The Automated System of Control of radioactive liquids effluents generated in Hospitals of Nuclear Medicine (SACEL) developed in the National Institute of Nuclear Research, it fulfills this regulation, besides improving the work conditions for the medical and technical personnel of the hospital in that are installed, since this system has the advantage of to be totally automated and to require of a minimum of attendance. The SACEL is an electro-hydraulic system of effluents control, based in the alternate operation of two decay deposits of the activity of the material contaminated with iodine-131. The system allows to take a registration of those volumes and liberated dose, besides being able to be monitoring in remote

  9. Department of Energy Nuclear Material Protection, Control, and Accounting Program at the Mangyshlak Atomic Energy Complex, Aktau, Republic of Kazakhstan

    Energy Technology Data Exchange (ETDEWEB)

    Case, R.; Berry, R.B.; Eras, A. [and others

    1998-08-01

    As part of the Cooperative Threat Reduction Nuclear Material Protection, Control, and Accounting (MPC and A) Program, the US Department of Energy and Mangyshlak Atomic Energy Complex (MAEC), Aktau, Republic of Kazakstan have cooperated to enhance existing MAEC MPC and A features at the BN-350 liquid-metal fast-breeder reactor. This paper describes the methodology of the enhancement activities and provides representative examples of the MPC and A augmentation implemented at the MAEC.

  10. El uso de la información de agencia en las ediciones electrónicas de diarios en España

    Directory of Open Access Journals (Sweden)

    David Sancha

    2005-11-01

    Full Text Available Los diarios de información general disponen en Internet de servicios de información on line actualizados permanentemente, que tienen en las agencias de noticias su fuente informativa fundamental. La urgencia por la publicación y la necesidad de llevar a cabo una actualización acumulativa lleva a una reelaboración mínima de los despachos que sirven las agencias y genera una homogeneización de los contenidos que se publican en los servicios on line de los distintos diarios. La presente investigación aborda mediante datos estadísticos, análisis de casos y entrevistas cómo los matices editoriales de cada publicación se diluyen en la redacción de las noticias y cada medio se ve obligado a buscar nuevos elementos informativos donde imprimir su carácter ideológico y diferenciar su producto de la competencia.

  11. Controlling the atom. The beginnings of nuclear regulation 1946--1962

    Energy Technology Data Exchange (ETDEWEB)

    Mazuzan, G.T.; Walker, J.S.

    1997-08-01

    This book traces the early history of nuclear power regulation in the US. It focuses on the Atomic Energy Commission (AEC), the federal agency that until 1975 was primarily responsible for planning and carrying out programs to protect public health and safety from the hazards of the civilian use of nuclear energy. It also describes the role of other groups that figured significantly in the development of regulatory policies, including the congressional Joint Committee on Atomic Energy, federal agencies other than the AEC, state governments, the nuclear industry, and scientific organizations. And it considers changes in public perceptions of and attitudes toward atomic energy and the dangers of radiation exposure. The context in which regulatory programs evolved is a rich and complex mixture of political, legislative, legal, technological, scientific, and administrative history. The basic purpose of this book is to provide the Nuclear Regulatory Commission (NRC), which inherited responsibility for nuclear safety after Congress disbanded the AEC, and the general public with information on the historical antecedents and background of regulatory issues.

  12. Microtubule Initiation from the Nuclear Surface Controls Cortical Microtubule Growth Polarity and Orientation in Arabidopsis thaliana

    Science.gov (United States)

    Ambrose, Chris; Wasteneys, Geoffrey O.

    2014-01-01

    The nuclear envelope in plant cells has long been known to be a microtubule organizing center (MTOC), but its influence on microtubule organization in the cell cortex has been unclear. Here we show that nuclear MTOC activity favors the formation of longitudinal cortical microtubule (CMT) arrays. We used green fluorescent protein (GFP)-tagged gamma tubulin-complex protein 2 (GCP2) to identify nuclear MTOC activity and GFP-tagged End-Binding Protein 1b (EB1b) to track microtubule growth directions. We found that microtubules initiate from nuclei and enter the cortex in two directions along the long axis of the cell, creating bipolar longitudinal CMT arrays. Such arrays were observed in all cell types showing nuclear MTOC activity, including root hairs, recently divided cells in root tips, and the leaf epidermis. In order to confirm the causal nature of nuclei in bipolar array formation, we displaced nuclei by centrifugation, which generated a corresponding shift in the bipolarity split point. We also found that bipolar CMT arrays were associated with bidirectional trafficking of vesicular components to cell ends. Together, these findings reveal a conserved function of plant nuclear MTOCs and centrosomes/spindle pole bodies in animals and fungi, wherein all structures serve to establish polarities in microtubule growth. PMID:25008974

  13. Microtubule initiation from the nuclear surface controls cortical microtubule growth polarity and orientation in Arabidopsis thaliana.

    Science.gov (United States)

    Ambrose, Chris; Wasteneys, Geoffrey O

    2014-09-01

    The nuclear envelope in plant cells has long been known to be a microtubule organizing center (MTOC), but its influence on microtubule organization in the cell cortex has been unclear. Here we show that nuclear MTOC activity favors the formation of longitudinal cortical microtubule (CMT) arrays. We used green fluorescent protein (GFP)-tagged gamma tubulin-complex protein 2 (GCP2) to identify nuclear MTOC activity and GFP-tagged End-Binding Protein 1b (EB1b) to track microtubule growth directions. We found that microtubules initiate from nuclei and enter the cortex in two directions along the long axis of the cell, creating bipolar longitudinal CMT arrays. Such arrays were observed in all cell types showing nuclear MTOC activity, including root hairs, recently divided cells in root tips, and the leaf epidermis. In order to confirm the causal nature of nuclei in bipolar array formation, we displaced nuclei by centrifugation, which generated a corresponding shift in the bipolarity split point. We also found that bipolar CMT arrays were associated with bidirectional trafficking of vesicular components to cell ends. Together, these findings reveal a conserved function of plant nuclear MTOCs and centrosomes/spindle pole bodies in animals and fungi, wherein all structures serve to establish polarities in microtubule growth. © The Author 2014. Published by Oxford University Press on behalf of Japanese Society of Plant Physiologists. All rights reserved. For permissions, please email: journals.permissions@oup.com.

  14. Remote-Controlled Robots Used for the Management of Severe Accident of the Fukushima Nuclear Power Plant

    Energy Technology Data Exchange (ETDEWEB)

    Cho, Jai Wan; Jeong, Kyung Min [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2011-10-15

    In this paper, remote-controlled robots, which have been used to stabilize and shut down the three troubled reactors (unit 1, 2 and 3) of the Fukushima nuclear power plant, are presented. From the press materials of NISA (nuclear and industrial safety agency), TEPCO (Tokyo electric power company) and the Yomiuri online news, we investigated the robots, which have been used for the management of severe accident of the Fukushima nuclear power plant. The military robots provided by USA, Packbot and Warrior, which are unmanned ground robots, have been sent into Unit 1 to Unit 3 to grasp the inside situation of reactor building and to record the radiation from the interior of reactors no. 1, 2, and 3. The Japanese robot, Quince, which was originally designed to be a rescue robot for disaster recovery, were modified and sent to carry out the installation of a water level gauge for the accumulated water in the basement of Unit 2. Unmanned military aerial robot, T-Hawk, provided by USA was used to check the status of rubbles around reactor building of Unit 1, 2, 3 and 4. And remote controlled construction robots made by Japan are used to clear outdoor rubbles by wireless remote control to improve working conditions

  15. AKT3 controls mitochondrial biogenesis and autophagy via regulation of the major nuclear export protein CRM-1.

    Science.gov (United States)

    Corum, Daniel G; Tsichlis, Philip N; Muise-Helmericks, Robin C

    2014-01-01

    Our previous work has shown that Akt3 is required for mitochondrial biogenesis in primary human endothelial cells (ECs) and in Akt3-null mice; Akt3 affects subcellular localization of peroxisome proliferator-activated receptor γ coactivator-1 (PGC-1α), the master regulator of mitochondrial biogenesis. The purpose of this study is to determine the mechanism by which Akt3 controls the subcellular distribution of PGC-1α and to explore the effect on mitochondrial biogenesis and turnover during angiogenesis. Here we use standard biochemical analyses and Akt3-knockdown strategies to show that Akt3 controls the stabilization of chromosome maintenance region-1 (CRM-1), the major nuclear export receptor. Site-directed mutagenesis and association analyses show that PGC-1α nuclear export is CRM-1 dependent. Akt3 knockdown and CRM-1 overexpression cause 3-fold reductions in PGC-1α target gene expression, compared to control levels. Akt3 inhibition causes autophagy, as measured by autophagosome formation, in a CRM-1-dependent, Akt1/mTOR-independent pathway. In vivo, Akt3-null and heterozygous mice show dose-dependent decreases in angiogenesis compared to wild-type littermates (~5- and 2.5-fold decreases, respectively), as assessed by Matrigel plug assays. This correlates with an ~1.5-fold decrease in mitochondrial Cox IV expression. Our studies suggest that Akt3 is a regulator of mitochondrial dynamics in the vasculature via regulation of CRM-1-dependent nuclear export.

  16. Nuclear entry of the circadian regulator mPER1 is controlled by mammalian casein kinase I epsilon.

    Science.gov (United States)

    Vielhaber, E; Eide, E; Rivers, A; Gao, Z H; Virshup, D M

    2000-07-01

    The molecular oscillator that keeps circadian time is generated by a negative feedback loop. Nuclear entry of circadian regulatory proteins that inhibit transcription from E-box-containing promoters appears to be a critical component of this loop in both Drosophila and mammals. The Drosophila double-time gene product, a casein kinase I epsilon (CKIepsilon) homolog, has been reported to interact with dPER and regulate circadian cycle length. We find that mammalian CKIepsilon binds to and phosphorylates the murine circadian regulator mPER1. Unlike both dPER and mPER2, mPER1 expressed alone in HEK 293 cells is predominantly a nuclear protein. Two distinct mechanisms appear to retard mPER1 nuclear entry. First, coexpression of mPER2 leads to mPER1-mPER2 heterodimer formation and cytoplasmic colocalization. Second, coexpression of CKIepsilon leads to masking of the mPER1 nuclear localization signal and phosphorylation-dependent cytoplasmic retention of both proteins. CKIepsilon may regulate mammalian circadian rhythm by controlling the rate at which mPER1 enters the nucleus.

  17. Status of nuclear medicine in Beijing: insights from the Beijing Quality Control Centre Survey 2005-2006.

    Science.gov (United States)

    Hongwei, Si; Jianhua, Geng; Shengzu, Chen

    2008-03-01

    To evaluate the status of nuclear medicine in Beijing during 2005. For evaluating the status, a survey was performed in September 2006 by postal questionnaires. Forty-two nuclear medicine departments in Beijing were investigated regarding staff, equipment and clinical applications. Up to January 2007, thirty nuclear medicine departments had responded to our survey (response rate, 71.4%). These departments employed a total of 321 staff (141 physicians, 122 technicians, seven physicists, 22 nurses and 29 other staff) and were equipped with 47 scanners (42 SPECT, three PET, two PET/CT) before September 2006. During 2005, these departments completed 88 135 scans (84 734 SPECT, 3401 PET), 462 246 radioimmunoassays and 2228 radioisotope treatment (1288 Graves' disease, 268 thyroid cancer, 166 bone metastasis, 506 other). Furthermore, eight major hospitals hired more highly qualified staff with greater experience, such as professors or associate professors, and who had more clinical applications than did non-majors. The percentage of the departments that conducted daily and monthly quality control procedures was 43.3% and 40.0%, respectively. Nuclear medicine departments in Beijing are on a considerable scale, but still have a long way to go in order to be well developed. Hospitals in Beijing should increase the number of physicists and perform QA/QC procedures more frequently.

  18. National phantoms bank for the service of nuclear medicine in Cuba. Utility for the quality control of the instrumentation; Banco de fantomas nacional para los servicios de medicina nuclear en Cuba. Utilidad para el control de calidad de la instrumentacion

    Energy Technology Data Exchange (ETDEWEB)

    Varela C, C.; Diaz B, M. [CCEEM, Calle 4 No. 455 (altos) e/19 y 21, Vedado, Ciudad Habana (Cuba); Lopez B, G.M. [CPHR, Calle 20 No. 4113 e/41 y 47, Playa Ciudad Habana (Cuba)]. e-mail: consuelo.varela@infomed.sld.cu

    2006-07-01

    Although, most of the applications in Nuclear Medicine have diagnostic ends, its going enlarging considerably the therapeutic applications. So that the diagnostic accuracy or the therapy effectiveness have not been affected, it becomes indispensable the quality control of the instrumentation, independently of its technological complexity and/or its exploitation period. Before the real lack of phantoms in the institutions, it was created a bank that puts to disposition of all the institutions, the existent phantoms in the country, and those that are going acquired, centralized by the State Control of Medical Equipment Center (CCEEM) and with Web access in its place www.eqmed.sld.cu. Having like base the elaboration of the National Protocol for the Quality Control of the Instrumentation in Nuclear Medicine that keeps in mind the international normative and the own existent conditions, were dictated and established two national regulations and its are being carried out the first audits to the instrumentation quality. These have evidenced the partial realization of the established quality controls in the services, the necessity to make aware as for the fulfillment of the criteria and quality concepts for the instrumentation, as well as the necessity to increase the phantoms number to the bank to guarantee the fulfillment of the Quality Control Programs. (Author)

  19. Is IQ in Childhood Associated with Suicidal Thoughts and Attempts? Findings from the Mater University Study of Pregnancy and Its Outcomes

    Science.gov (United States)

    Alati, Rosa; Gunnell, David; Najman, Jake; Williams, Gail; Lawlor, Debbie

    2009-01-01

    This study explores associations of IQ at age 14 with adult symptoms of suicidal thoughts and attempts at age 21. Analysis was based on the Mater University Study of Pregnancy and its outcomes, an Australian prospective birth cohort study started in Brisbane Australia in 1981. We assessed associations with suicide thoughts, plans, and attempts. We…

  20. Robust observer based control for axial offset in pressurized-water nuclear reactors based on the multipoint reactor model using Lyapunov approach

    Energy Technology Data Exchange (ETDEWEB)

    Zaidabadinejad, Majid; Ansarifar, Gholam Reza [Isfahan Univ. (Iran, Islamic Republic of). Dept. of Nuclear Engineering

    2017-11-15

    In nuclear reactor imbalance of axial power distribution induces xenon oscillations. These fluctuations must be maintained bounded within allowable limits. Otherwise, the nuclear power plant could become unstable. Therefore, bounded these oscillations is considered to be a restriction for the load following operation. Also, in order to design the nuclear reactor control systems, poisons concentrations, especially xenon must be accessible. But, physical measurement of these parameters is impossible. In this paper, for the first time, in order to estimate the axial xenon oscillations and ensures these oscillations are kept bounded within allowable limits during load-following operation, a robust observer based nonlinear control based on multipoint kinetics reactor model for pressurized-water nuclear reactors is presented. The reactor core is simulated based on the multi-point nuclear reactor model (neutronic and thermal-hydraulic). Simulation results are presented to demonstrate the effectiveness of the proposed observer based controller for the load-following operation.

  1. Radiological protection and routinary controls of an activimeter with a cesium and barium sources in an nuclear medicine center; Proteccion radiologica y controles rutinarios de un activimetro con fuentes de cesio y bario en un centro de medicina nuclear

    Energy Technology Data Exchange (ETDEWEB)

    Morales L, M.E. [IPEN INEN, Centro de Medicina Nuclear, Av. Aviacion 3799, Lima 34 (Peru)]. e-mail: toyoco3000@hotmail.com

    2006-07-01

    In the present work the results when carrying out the routine controls in a Deluxe Isotope (Calibrator II) equipment, with some sources of Cesium 137 and Barium 133, in a Nuclear Medicine Center that operates from the year 1983 in a modern one construction inside the Institute of Neoplastic Illnesses (INEN) are shown. Taking in account the Radiological Protection measures to verify if the equipment responds to the personnel's demands in the measurements of activities of the diverse radionuclides that are used in different types of exams that are carried out in this Nuclear Medicine Center are the objectives of this work. This Center was equipped initially with donated equipment by the International Atomic Energy Agency (IAEA) with those that it develops assistance, educational works and of research, giving services to patients of the INEN and other public and private medical centers. (Author)

  2. O Brasil, a AIEA e o Regime de Não Proliferação Nuclear (1957-2014: entre a cooperação e a desconfiança.

    Directory of Open Access Journals (Sweden)

    Edson José Perosa

    2014-10-01

    Full Text Available A AIEA foi criada em 1957 após a proposta ‘‘átomos para paz’’ do presidente estadunidense Eisenhower, apresentada na ONU em 1953. A Agência deveria promover o uso pacífico da energia nuclear e coibir seu uso militar. O Tratado de Não Proliferação Nuclear (TNP, por sua vez, foi aprovado em 1968 e entrou em vigor em 1970. Os países que aderissem a esse tratado se comprometiam em não desenvolver armas nucleares e, por sua vez, os que já dispunham desses armamentos se comprometiam em reduzir seus arsenais. Esses são dois dos principais instrumentos do regime de não proliferação nuclear. O Brasil adotou uma postura crítica em relação ao TNP, criticando-o como sendo discriminatório. Com relação à AIEA, o governo brasileiro manteve contatos com a Agência e firmou tratados com ela – como o tratado tripartite Brasil-RFA-AIEA e o tratado quadripartite Brasil-Argentina-AIEA-ABACC.  Diferentemente de outros atores do regime de não proliferação, o Brasil pareceu mais disposto a aceitar a tutela da AIEA, ainda que não aderisse integralmente às salvaguardas da Agência. Ademais, a Agência – por meio dos tratados assinados com ela – pode ter sido um meio para o Brasil tentar legitimar seu programa nuclear como pacífico.

  3. A dynamic failure evaluation of a simplified digital control system of a nuclear power plant pressurizer

    Energy Technology Data Exchange (ETDEWEB)

    Pinto, J.M.O.; Melo, P.F. Frutuoso e, E-mail: jpinto@nuclear.ufrj.b, E-mail: frutuoso@nuclear.ufrj.b [Universidade Federal do Rio de Janeiro (UFRJ), RJ (Brazil); Saldanha, P.L.C., E-mail: plsaldanha@gmail.co, E-mail: pedroabeu@gmail.co [Associacao Brasileira de Ensino Universitario (UNIABEU), Nova Iguacu, RJ (Brazil)

    2010-07-01

    Given the increasing use of digital systems in nuclear power plants, a specific approach to reliability and risk analysis has been required. The digital system reflects many interactions between hardware, software, process variables, and human actions. At the same time, the software, does not have a reliability approach as well-defined as the one existing for the other physical components of the system. Then, its reliability analysis is still under development due to difficulties arising from the complexity, flexibility and interactions present in such systems.The traditional approach of using fault trees is static and does not approach the dynamic interactions in such systems, such as delays in capture and processing information, memory, logic loops, system states, etc. It is necessary to find a reliability methodology that takes into account these issues without violating the existing requirements concerning safety analysis, such as: ability to distinguish between common-cause failures, availability of relevant information to users, like minimal cut sets, and failure probabilities as long as the possibility of incorporating the results into existing probabilistic safety assessments (PSA).One approach is to trace all the possible errors of the digital system through dynamic methodologies. The DFM (Dynamic Flow-graph Methodology) is one of the methodologies that better meets the requirements for modeling dynamic systems. It discretizes the most relevant variables of the analyzed system in states that reflect their behavior, sets the logic that connects them through decision tables and finally performs a system analysis, aiming, for example, the root causes (prime implicants) of a given top event of failure. Three aspects have been addressed, the modeling of the system itself, the incorporation of results to probabilistic safety analyses and identification of software failures.To illustrate the DFM, a simplified digital control system of a typical PWR pressurizer

  4. A proposal for phosphor imager acceptance testing procedure and routine quality controls in nuclear pharmacy practice.

    Science.gov (United States)

    Urbano, Nicoletta; Modoni, Sergio

    2011-07-01

    The digital autoradiography system is currently used in nuclear medicine for quantitative imaging of radioactivity distribution (thin layer chromatography samples, tissue sections, and cell cultures). The aim of this study was to define a set of tests for setting up a specific acceptance testing procedure and routine quality controls for this instrument. Over a 3-month period, we analyzed the active components of the instrument (phosphor screen and photometer) by using suitable self-manufactured equipment (phantoms, lead plate, lead cylinder, and photographic paper) required to realize, in a routine quality program, the following tests: integral uniformity (IU) and differential uniformity (DU) in a useful field of view (UFOV) and a central field of view (CFOV), resolution, geometric linearity, and sensitivity. Screen IU was 19.7 ± 2.3% (UFOV) and 11.1 ± 3.7% (CFOV). Screen DU ranged between 1.6 ± 1.1 and 1.8 ± 0.9% for UFOV and between 1.2 ± 0.4 and 1.4 ± 0.6% for CFOV. Screen resolution measured as full-width at half-maximum was 1.94 ± 0.08 mm. Screen sensitivity was 505.1 ± 10.4 digital light units and ranged between -3.15 and +3.49% with reference to the mean of measured values. Photometer IU was 17.4 ± 0.2% (UFOV) and 13.7 ± 1.1% (CFOV). Photometer DU ranged between 1.9 ± 0.9 and 2.3 ± 1.2% for UFOV and between 1.9 ± 0.8 and 2.1 ± 1.1% for CFOV. Photometer resolution was good (full-width at half-maximum =0.5 ± 0.076 mm). Our results suggest that the methodology we propose could be an easy, accurate, quick, and low-cost tool to guarantee the correct instrument basic function.

  5. Assessing controls on perched saturated zones beneath the Idaho Nuclear Technology and Engineering Center, Idaho

    Science.gov (United States)

    Mirus, Benjamin B.; Perkins, Kim S.; Nimmo, John R.

    2011-01-01

    Waste byproducts associated with operations at the Idaho Nuclear Technology and Engineering Center (INTEC) have the potential to contaminate the eastern Snake River Plain (ESRP) aquifer. Recharge to the ESRP aquifer is controlled largely by the alternating stratigraphy of fractured volcanic rocks and sedimentary interbeds within the overlying vadose zone and by the availability of water at the surface. Beneath the INTEC facilities, localized zones of saturation perched on the sedimentary interbeds are of particular concern because they may facilitate accelerated transport of contaminants. The sources and timing of natural and anthropogenic recharge to the perched zones are poorly understood. Simple approaches for quantitative characterization of this complex, variably saturated flow system are needed to assess potential scenarios for contaminant transport under alternative remediation strategies. During 2009-2011, the U.S. Geological Survey (USGS), in cooperation with the U.S. Department of Energy, employed data analysis and numerical simulations with a recently developed model of preferential flow to evaluate the sources and quantity of recharge to the perched zones. Piezometer, tensiometer, temperature, precipitation, and stream-discharge data were analyzed, with particular focus on the possibility of contributions to the perched zones from snowmelt and flow in the neighboring Big Lost River (BLR). Analysis of the timing and magnitude of subsurface dynamics indicate that streamflow provides local recharge to the shallow, intermediate, and deep perched saturated zones within 150 m of the BLR; at greater distances from the BLR the influence of streamflow on recharge is unclear. Perched water-level dynamics in most wells analyzed are consistent with findings from previous geochemical analyses, which suggest that a combination of annual snowmelt and anthropogenic sources (for example, leaky pipes and drainage ditches) contribute to recharge of shallow and

  6. SMRT repression of nuclear receptors controls the adipogenic set point and metabolic homeostasis

    NARCIS (Netherlands)

    Nofsinger, Russell R.; Li, Pingping; Hong, Suk-Hyun; Jonker, Johan W.; Barish, Grant D.; Ying, Hao; Cheng, Sheue-Yann; LeBlanc, Mathias; Xu, Wei; Pei, Liming; Kang, Yeon-Joo; Nelson, Michael; Downes, Michael; Yu, Ruth T.; Olefsky, Jerrold M.; Lee, Chih-Hao; Evans, Ronald M.

    2008-01-01

    The nuclear receptor corepressor, silencing mediator of retinoid and thyroid hormone receptors (SMRT), is recruited by a plethora of transcription factors to mediate lineage and signal-dependent transcriptional repression. We generated a knockin mutation in the receptor interaction domain (RID) of

  7. Star-PAP Control of BIK Expression and Apoptosis Is Regulated by Nuclear PIPKIα and PKCδ Signaling

    Science.gov (United States)

    Li, Weimin; Laishram, Rakesh S.; Ji, Zhe; Barlow, Christy A.; Tian, Bin; Anderson, Richard A.

    2012-01-01

    SUMMARY BIK protein is an initiator of mitochondrial apoptosis and BIK expression is induced by pro-apoptotic signals including DNA damage. Here we demonstrate that 3′-end processing and expression of BIK mRNA are controlled by the nuclear PI4,5P2-regulated poly(A) polymerase Star-PAP downstream of DNA damage. Nuclear PKCδ is a key mediator of apoptosis and DNA damage stimulates PKCδ association with the Star-PAP complex where PKCδ is required for Star-PAP-dependent BIK expression. PKCδ binds the PI4,5P2-generating enzyme PIPKIα, which is essential for PKCδ interaction with the Star-PAP complex and PKCδ activity is directly stimulated by PI4,5P2. Features in the BIK 3′-UTR uniquely define Star-PAP specificity and may block canonical PAP activity toward BIK mRNA. This reveals a nuclear phosphoinositide signaling nexus where PIPKIα, PI4,5P2 and PKCδ regulate Star-PAP control of BIK expression and induction of apoptosis. This pathway is distinct from the Star-PAP-mediated oxidative stress pathway indicating signal-specific regulation of mRNA 3′-end processing. PMID:22244330

  8. Comparison of the Standards applied to Instrumentation and Control Systems for Nuclear Power Stations in Korea and Russia

    Energy Technology Data Exchange (ETDEWEB)

    Park, Joo Hyun; Hwang, In Koo; Lee, Dong Young

    2005-04-15

    This report describes a comparison result of technical standards applied to instrumentation and control systems for nuclear power plants between in Korea and in Russia. Russia also has a state-run organization authorized to conduct approval, cancellation, and audit in use of nuclear facility or equipment. The Russian standards for nuclear instrumentation and control equipment are analogous with the Korean ones in the aspect of basic concepts and principles. However, there are some differences in document structure, design requirements, qualification test items, depth of contents between two standard systems. The biggest deviation exists in the standard documents for seismic qualification and electromagnetic interference qualification. Korean seismic qualification standard utilizing US approach, defines testing and qualification methods specifically and clearly. Russian standards however provide only conceptual definitions and requirements in the seismic related aspects. Therefore, it is conceived that any equipment or system qualified seismically in accordance with Korean standards should additionally provide technical evidence that it is satisfactory with Russian standards as well. In electromagnetic interference qualification, because Russian standard requires more testing items than the current Korean standard, the additional qualification tests are necessary to meet the Russian requirements. However, these additional test items are based on IEC(International Electrotechnical Commission), therefore it is not a problem to perform those tests in a Korean testing facility.

  9. Active Interrogation using Photofission Technique for Nuclear Materials Control and Accountability

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Haori [Oregon State Univ., Corvallis, OR (United States)

    2016-03-31

    Innovative systems with increased sensitivity and resolution are in great demand to detect diversion and to prevent misuse in support of nuclear materials management for the U.S. fuel cycle. Nuclear fission is the most important multiplicative process involved in non-destructive active interrogation. This process produces the most easily recognizable signature for nuclear materials. In addition to thermal or high-energy neutrons, high-energy gamma rays can also excite a nucleus and cause fission through a process known as photofission. Electron linear accelerators (linacs) are widely used as the interrogating photon sources for inspection methods involving photofission technique. After photofission reactions, prompt signals are much stronger than the delayed signals, but it is difficult to quantify them in practical measurements. Delayed signals are easily distinguishable from the interrogating radiation. Linac-based, advanced inspection techniques utilizing the delayed signals after photofission have been extensively studied for homeland security applications. Previous research also showed that a unique delayed gamma ray energy spectrum exists for each fissionable isotope. In this work, high-energy delayed γ-rays were demonstrated to be signatures for detection, identification, and quantification of special nuclear materials. Such γ-rays were measured in between linac pulses using independent data acquisition systems. A list-mode system was developed to measure low-energy delayed γ-rays after irradiation. Photofission product yields of 238U and 239Pu were determined based on the measured delayed γ-ray spectra. The differential yields of delayed γ-rays were also proven to be able to discriminate nuclear from non-nuclear materials. The measurement outcomes were compared with Monte Carlo simulation results. It was demonstrated that the current available codes have capabilities and limitations in the simulation of photofission process. A two

  10. Sipping machine control system new design to perform integrity of nuclear fuel test in Cofrentes power plant

    Energy Technology Data Exchange (ETDEWEB)

    Palomo, M., E-mail: mpalomo@iqn.upv.es [Departamento de Ingenieria Quimica y Nuclear. Universidad Politecnica de Valencia (Spain); Urrea, M., E-mail: Matias.urrea@iberdrola.es [C.N.Cofrentes - Iberdrola Generacion S.A., Cofrentes, Valencia (Spain); Curiel, M., E-mail: m.curiel@lainsa.com [LAINSA Grupo Dominguis, Valencia (Spain); Arnaldos, A., E-mail: a.arnaldos@titaniast.com [TITANIA Servicios Tecnologicos SL, Grupo Dominguis, Valencia (Spain)

    2011-07-01

    This paper we present is related to SIPPING machine control system new design to perform integrity of nuclear fuel test. This test is a non destructive technique used for evaluating the radiated nuclear fuel coating structural integrity. It is based on the radioactive emission detection of fission elements in the reactor cooling system, using the fuel inspection equipment (SIPPING). SIPPING equipment consists of one simultaneous test bell-shaped vessel of eight fuel elements, and another one for individual element test, a control workstation and some accessories (cables, thermocouples, hoses). SIPPING inspection is carried out by means of fuel element vessel. Through air injection, water flows around the element and heat evacuation is reduced, so fuel elements temperature increases. Those elements with faults shall expelled fission components dissolved in water and/or as a gas component. The project aim is the SIPPING system control design and software based on LabVIEW, for control, monitoring and documentation of the SIPPING Test. This project shall give a major functionality to the system and, at the same time, shall facilitate the user a friendlier and interactive environment allowing: to substitute the present work platform with a real-time electronic system based on cRIO and a control software ad-hoc designed for SIPPING system; to equip new system of a major redundancy for data storage, minimising loss probability of the same. (author)

  11. Sipping machine control system new design to perform integrity of nuclear fuel test in Cofrentes power plant

    Energy Technology Data Exchange (ETDEWEB)

    Curiel, M. [Logistica y Acondicionamientos Industriales SAU, Sorolla Center, local 10, Av. de las Cortes Valencianas No. 58, 46015 Valencia (Spain); Palomo, M. J. [ISIRYM, Universidad Politecnica de Valencia, Camino de Vera s/n, Valencia (Spain); Urrea, M. [Iberdrola Generacion S. A., Central Nuclear Cofrentes, Carretera Almansa Requena s/n, 04662 Cofrentes, Valencia (Spain); Vaquer, J., E-mail: m.curiel@lainsa.co [TITANIA Servicios Tecnologicos SL, Sorolla Center, local 10, Av. de las Cortes Valencianas No. 58, 46015 Valencia (Spain)

    2010-10-15

    This paper related to Sipping machine control system new design to perform integrity of nuclear fuel test. This test is a non destructive technique used for evaluating the radiated nuclear fuel coating structural integrity. It is based on the radioactive emission detection of fission elements in the reactor cooling system, using the fuel inspection equipment Sipping. The equipment consists of one simultaneous test bell-shaped vessel of eight fuel elements, and another one for individual element test, a control workstation and some accessories (cables, thermocouples, hoses). Sipping inspection is carried out by means of fuel element vessel. Through air injection, water flows around the element and heat evacuation is reduced, so fuel elements temperature increases. Those elements with faults shall expelled fission components dissolved in water and/or as a gas component. The project aim is the Sipping system control design and software based on LabVIEWTM, for control, monitoring and documentation of the Sipping test. This project shall give a major functionality to the system and, at the same time, shall facilitate the user a friendlier and interactive environment allowing: 1) To substitute the present work platform with a real-time electronic system based on cRIO and a control software ad-hoc designed for Sipping system. 2) To equip new system of a major redundancy for data storage, minimising loss probability of the same. (Author)

  12. Spectroscopic On-Line Monitoring for Process Control and Safeguarding of Radiochemical Streams in Nuclear Fuel Reprocessing Facilities

    Energy Technology Data Exchange (ETDEWEB)

    Bryan, Samuel A.; Levitskaia, Tatiana G.; Casella, Amanda J.; Peterson, James M.; Johnsen, Amanda M.; Lines, Amanda M.; Thomas, Elizabeth M.

    2011-03-01

    The current book chapter presents preliminary work toward the use of spectroscopic on-line monitoring for process control and safeguarding of radiochemical streams. Raman spectroscopy was demonstrated as a method for determining U(VI), nitrate, and nitric acid, while visible-near-infrared (vis-NIR) spectroscopy was demonstrated as a method for determining Pu(IV), Np(V), U(VI) and Nd(III). This method has been established using fuel reprocessing solution stimulants under dynamic flow conditions and on commercial spent nuclear fuel samples. Partial least squares (PLS) models for each analyte were prepared, and the fits of the data presented. A brief review of literature relevant to the use of vibrational spectroscopy and physicochemical measurements for process monitoring of nuclear fuel solutions is reported.

  13. Simulation of the control systems of the Laguna Verde nuclear power station; Simulacion de los sistemas de control de la Central Laguna Verde

    Energy Technology Data Exchange (ETDEWEB)

    Arjona L, Marco Antonio; Rodriguez Lozano, Saul [Instituto de Investigaciones Electricas, Cuernavaca (Mexico)

    1992-03-01

    In this article, the control systems modeled in the Laguna Verde Nuclear Power Station (CNLV) simulator, are presented. A functional description of each one of them is given and the way they were modeled for their simulation in real time, is also described. [Espanol] En este articulo, se presentan los sistemas de control modelados en el simulador de la Central Laguna Verde (CLV). Se da una descripcion funcional de cada uno de ellos y se describe la forma en que fueron modelados para su simulacion en tiempo real.

  14. Delegation, Presidential Regimes, and Latin American Regulatory Agencies Delegación, regimenes presidenciales y agencias reguladoras en América Latina

    Directory of Open Access Journals (Sweden)

    Jacint Jordana

    2010-04-01

    Full Text Available During the 1990s, a large number of regulatory agencies were created or reformed in different sectors in Latin American countries. Almost all included political delegation mechanisms, intended as formal rules to enhance credible commitments to time-consistent policies. In this paper, using an original data set of agencies’ head tenure in the telecommunications and finance regulatory agencies, we discuss if these mechanisms worked as planned, and find a divergence between actual mandates and the formally established fixed terms, effected by means of systematic early resignations. Our findings reveal, however, some consistent patterns of behavior. Stronger legislative presidential power reduced effective delegation to some extent, and agencies’ organizational strengths protected them from patron-age. We also confirmed the existence of some significant differences be-tween the two sectors examined. Having slightly weaker delegation rules, delegation practices were also less effective in telecommunications than in financial services, contrary to expectations about credible commitments. Durante los años 1990, muchas agencias reguladoras fueron creadas o reformadas en diferentes sectores en los países latinoamericanos. Casi todas incluyeron mecanismos de delegación política, entendidos como reglas formales para mejorar los compromisos creíbles sobre políticas que requieren coherencia en el tiempo. En este trabajo, utilizando un conjunto de datos originales sobre los responsables de las agencias reguladoras de las telecomunicaciones y de las finanzas, se discute si estos mecanismos funcionaron como estaba previsto, identificándose una divergencia entre los mandatos reales y los términos formalmente establecidos, debido a la existencia de numerosas renuncias anticipadas. Nuestros hallazgos revelan, sin embargo, algunos patrones consistentes de comportamiento: un mayor poder presidencial sobre el legislativo reduce la delegación efectiva

  15. FAULT DIAGNOSIS WITH MULTI-STATE ALARMS IN A NUCLEAR POWER CONTROL SIMULATOR

    Energy Technology Data Exchange (ETDEWEB)

    Austin Ragsdale; Roger Lew; Brian P. Dyre; Ronald L. Boring

    2012-10-01

    This research addresses how alarm systems can increase operator performance within nuclear power plant operations. The experiment examined the effect of two types of alarm systems (two-state and three-state alarms) on alarm compliance and diagnosis for two types of faults differing in complexity. We hypothesized three-state alarms would improve performance in alarm recognition and fault diagnoses over that of two-state alarms. We used sensitivity and criterion based on Signal Detection Theory to measure performance. We further hypothesized that operator trust would be highest when using three-state alarms. The findings from this research showed participants performed better and had more trust in three-state alarms compared to two-state alarms. Furthermore, these findings have significant theoretical implications and practical applications as they apply to improving the efficiency and effectiveness of nuclear power plant operations.

  16. Current perspectives on the role of TRAMP in nuclear RNA surveillance and quality control

    OpenAIRE

    Pan K; Huang Z; Lee JTH; Wong CM

    2015-01-01

    Kewu Pan, Zhe Huang, Jimmy Tsz Hang Lee, Chi-Ming Wong State Key Laboratory of Pharmaceutical Biotechnology, Department of Medicine, Shenzhen Institute of Research and Innovation, the University of Hong Kong, Pokfulam, Hong Kong Abstract: The TRAMP complex assists the nuclear exosome to degrade a broad range of ribonucleic acid (RNA) substrates by increasing both exoribonucleolytic activity and substrate specificity. However, how the interactions between the TRAMP subunits and the components...

  17. ADF and Cofilin1 Control Actin Stress Fibers, Nuclear Integrity, and Cell Survival.

    Science.gov (United States)

    Kanellos, Georgios; Zhou, Jing; Patel, Hitesh; Ridgway, Rachel A; Huels, David; Gurniak, Christine B; Sandilands, Emma; Carragher, Neil O; Sansom, Owen J; Witke, Walter; Brunton, Valerie G; Frame, Margaret C

    2015-12-01

    Genetic co-depletion of the actin-severing proteins ADF and CFL1 triggers catastrophic loss of adult homeostasis in multiple tissues. There is impaired cell-cell adhesion in skin keratinocytes with dysregulation of E-cadherin, hyperproliferation of differentiated cells, and ultimately apoptosis. Mechanistically, the primary consequence of depleting both ADF and CFL1 is uncontrolled accumulation of contractile actin stress fibers associated with enlarged focal adhesions at the plasma membrane, as well as reduced rates of membrane protrusions. This generates increased intracellular acto-myosin tension that promotes nuclear deformation and physical disruption of the nuclear lamina via the LINC complex that normally connects regulated actin filaments to the nuclear envelope. We therefore describe a pathway involving the actin-severing proteins ADF and CFL1 in regulating the dynamic turnover of contractile actin stress fibers, and this is vital to prevent the nucleus from being damaged by actin contractility, in turn preserving cell survival and tissue homeostasis. Copyright © 2015 The Authors. Published by Elsevier Inc. All rights reserved.

  18. Nuclear medicine scans in Beijing: insights from the Beijing Quality Control Centre Survey 2005-2006.

    Science.gov (United States)

    Hongwei, Si; Jianhua, Geng; Shengzu, Chen

    2007-08-01

    To survey nuclear medicine scans carried out in Beijing during 2005. Forty-two nuclear medicine departments were surveyed by using mailed questionnaires sent during September 2006. By the end of January 2007, 30 out of 42 hospitals had replied to our survey. The estimated annual number of SPECT procedures was 6.72 per 1000 population during 2005. Among SPECT applications, whole-body bone scans (n=23,090) were performed with the highest frequency, followed by myocardial perfusion imaging (n=19,092), and renal function imaging (n=10,287). The estimated number of myocardial perfusion scintigraphy scans was 1530 procedures per million population. The annual number of PET procedures was 0.25 per 1000 population. Most of these PET and SPECT examinations used relative monotonous radiotracers and most patients were in the age group of 40-70 years. However, for each cancer and each type of application, age distributions slightly varied. In addition, the analysis of gender distribution revealed that the number of male patients was higher than for female patients. The number of nuclear medicine scans carried out in Beijing during 2005 was considerable, with unbalanced clinical applications. Excluded myocardial perfusion scintigraphy, the frequencies of some applications were still lower than in western countries. Furthermore, most procedures used relatively monotonous radiotracers. Most patients were in the age group of 40-70 years and were male.

  19. Nuclear calcium controls the apoptotic-like cell death induced by d-erythro-sphinganine in tobacco cells.

    Science.gov (United States)

    Lachaud, Christophe; Da Silva, Daniel; Cotelle, Valérie; Thuleau, Patrice; Xiong, Tou Cheu; Jauneau, Alain; Brière, Christian; Graziana, Annick; Bellec, Yannick; Faure, Jean-Denis; Ranjeva, Raoul; Mazars, Christian

    2010-01-01

    Studies performed in animals have highlighted the major role of sphingolipids in regulating the balance between cell proliferation and cell death. Sphingolipids have also been shown to induce cell death in plants via calcium-based signalling pathways but the contribution of free cytosolic and/or nuclear calcium in the overall process has never been evaluated. Here, we show that increase in tobacco BY-2 cells of the endogenous content of Long Chain Bases (LCBs) caused by external application of d-erythro-sphinganine (DHS) is followed by immediate dose-dependent elevations of cellular free calcium concentration within the first minute in the cytosol and 10min later in the nucleus. Cells challenged with DHS enter a death process through apoptotic-like mechanisms. Lanthanum chloride, a general blocker of calcium entry, suppresses the cellular calcium variations and the PCD induced by DHS. Interestingly, dl-2-amino-5-phosphopentanoic acid (AP5) and [(+)-dizocilpine] (MK801), two inhibitors of animal and plant ionotropic glutamate receptors, suppress DHS-induced cell death symptoms by selectively inhibiting the variations of nuclear calcium concentration. The selective action of these compounds demonstrates the crucial role of nuclear calcium signature in controlling DHS-induced cell death in tobacco cells. 2009 Elsevier Ltd. All rights reserved.

  20. Human factors design, verification, and validation for two types of control room upgrades at a nuclear power plant

    Energy Technology Data Exchange (ETDEWEB)

    Boring, Laurids Ronald [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2014-10-01

    This paper describes the NUREG-0711 based human factors engineering (HFE) phases and associated elements required to support design, verification and validation (V&V), and implementation of a new plant process computer (PPC) and turbine control system (TCS) at a representative nuclear power plant. This paper reviews ways to take a human-system interface (HSI) specification and use it when migrating legacy PPC displays or designing displays with new functionality. These displays undergo iterative usability testing during the design phase and then undergo an integrated system validation (ISV) in a full scope control room training simulator. Following the successful demonstration of operator performance with the systems during the ISV, the new system is implemented at the plant, first in the training simulator and then in the main control room.

  1. An Investigation for Arranging the Video Display Unit Information in a Main Control Room of Advanced Nuclear Power Plants

    Energy Technology Data Exchange (ETDEWEB)

    Hsu, Chong Cheng; Yang, Chih Wei [Institute of Nuclear Energy Research, Atomic Energy Council, Taoyuan (China)

    2014-08-15

    Current digital instrumentation and control and main control room (MCR) technology has extended the capability of integrating information from numerous plant systems and transmitting needed information to operations personnel in a timely manner that could not be envisioned when previous generation plants were designed and built. A MCR operator can complete all necessary operating actions on the video display unit (VDU). It is extremely flexible and convenient for operators to select and to control the system display on the screen. However, a high degree of digitalization has some risks. For example, in nuclear power plants, failures in the instrumentation and control devices could stop the operation of the plant. Human factors engineering (HFE) approaches would be a manner to solve this problem. Under HFE considerations, there exists 'population stereotype' for operation. That is, the operator is used to operating a specific display on the specific VDU for operation. Under emergency conditions, there is possibility that the operator will response with this habit population stereotype, and not be aware that the current situation has already changed. Accordingly, the advanced nuclear power plant should establish the MCR VDU configuration plan to meet the consistent teamwork goal under normal operation, transient and accident conditions. On the other hand, the advanced nuclear power plant should establish the human factors verification and validation plan of the MCR VDU configuration to verify and validate the configuration of the MCR VDUs, and to ensure that the MCR VDU configuration allows the operator shift to meet the HFE consideration and the consistent teamwork goal under normal operation, transient and accident conditions. This paper is one of the HF V V plans of the MCR VDU configuration of the advanced nuclear power plant. The purpose of this study is to confirm whether the VDU configuration meets the human factors principles and the consistent

  2. Page 1 Bull. Mater. Sci., Vol. 6, No. 6, December 1984, pp. 971–977 ...

    Indian Academy of Sciences (India)

    indispensable tools for vapour deposition of materials (Holland 1956; Chopra 1969;. Jackson 1970; Maissel and Glang 1970). The technique offers manifold advantages over the other conventional methods such as thermal (resistive heating) and electron beam evaporation when a precise control over the film composition, ...

  3. Page 1 Bull. Mater. Sci., Vol. 6, No. 1, February 1984, pp. 99-104. (C ...

    Indian Academy of Sciences (India)

    (unnotched) of some of these imide-amine and epoxy/glass fabric composites were found to be better than the control. Keywords. Imide-amine hardness; epoxy resin. 1. Introduction. Epoxy resins constitute one of the most important class of matrix materials in high performance composite systems. This is due to their ...

  4. Análisis de puestos del Departamento de Crédito de la Agencia de Esparza del Banco Nacional de Costa Rica y propuesta de soluciones

    OpenAIRE

    Rojas Hernández, Ronald

    2007-01-01

    Tesis de maestría -- Universidad de Costa Rica. Posgrado en Administración y Dirección de Empresas. Maestría Profesional en Administración y Dirección de Empresas, 2007 El objetivo general es “evaluar la situación actual del análisis de puestos en el Departamento de Crédito de la Agencia de Esparza del Banco Nacional de Costa Rica para plantear una propuesta de soluciones a los problemas que se detecten”. Aparte los objetivos específicos son: a) Exponer las bases teóricas del análisis de p...

  5. Las competencias en la educación superior: tecnologías de gobierno para la gestión de la capacidad de agencia

    Directory of Open Access Journals (Sweden)

    Olga Cecilia Díaz Flórez

    2014-02-01

    Full Text Available El artículo sitúa las competencias como tecnología propia de un gobierno social gestado desde el neoliberalismo, cuyas prácticas de regulación son fortalecidas tanto con las políticas de los organismos internacionales como desde las políticas oficiales del país, destacando cómo en unos y otros se impulsan unas formas de gobierno flexible, pragmático, que responde adaptativamente a los cambios y que, sin embargo, favorecen prácticas que abren espacios a las fisuras, las contraconductas, los antagonismos: de un lado, con la promoción de la capacidad de agencia, y, de otro, con los escenarios que generan apertura, a través del impulso a la modulación y la automodulación.

  6. Implementation of a quality control program of the equipment of the nuclear medicine services in Chile; Implementacion de un programa de control de calidad del equipamiento de los servicios de medicina nuclear de Chile

    Energy Technology Data Exchange (ETDEWEB)

    Astudillo, R.; Diaz, G.; Ferreira, A.; Garcia, M.; Hermosilla, A.; Pacheco, F.; Vasquez, M. [Universidad de la Frontera, Departamento de Ciencias Fisicas, Av. Francisco Salazar 1145, Temuco 4811230, Araucania (Chile); Coca, M., E-mail: ferreira.sdgr@gmail.com [MedScan Concepcion, Paicavi 270, Concepcion (Chile)

    2014-08-15

    Now days in Chile there are more of 43 Nuclear Medicine centers; most of them have gamma cameras in order to study physiological process in diagnostic and treatment of patients pathologies. This requires having the equipment in optimal operating condition and it is ensured with quality control programs that are based on a series of tests relating to protocols, such as TECDOC-602 y AAPM No.6. Planar test often applied in gamma cameras including: spatial resolution, spatial linearity, sensitivity and uniformity. SPECT tests consider: tomography uniformity, rotation center tomography resolution and total performance. The tests in dose calibrator are: background measurement, accuracy, precision, linearity and reproducibility. The tests above require the use of radioactive sources and specific simulators patterns or phantom based on international standards such as The National Electrical Manufacturers Association (Nema), International Atomic Energy Agency (IAEA) and The American Association of Medical Physics (AAPM). In this work we carried out several tests of quality control in a Nuclear Medicine Center of Temuco and we propose to implement the applied methodology in others similar Chilean centers. (author)

  7. Prioridades de intervención para la fase aguda de las emergencias complejas formuladas por nueve agencias de ayuda humanitaria

    Directory of Open Access Journals (Sweden)

    Carmen Sofía Carrillo Jaimes

    2004-01-01

    Full Text Available Las Emergencias Complejas son un problema de Salud Pública internacional de frecuencia y magnitud crecientes que producen una importante mortalidad y morbilidad especialmente durante su fase aguda. El objetivo de este estudio es identificar y analizar las áreas prioritarias de intervención en la fase aguda de una emergencia compleja formuladas en los manuales operativos de las principales agencias de ayuda, así como el nivel de desarrollo y estructuración de las actividades propuestas en cada área de prioridad. Métodos: Como material de estudio se utilizaron los manuales de intervención elaborados por 9 de las principales agencias de ayuda. Se procedió a un análisis cuantitativo de las 16 prioridades de intervención planteadas así como del nivel de formulación de cada prioridad en base al desarrollo de 73 variables o aspectos de las propuestas formuladas en los manuales. Resultados: El manual de ACNUR recoge el 90% de las 73 variables de desarrollo de las prioridades y el de Oficina de Coordinación de Asuntos Humanitarios de Naciones Unidas el 35% de las 73 variables. ACNUR presenta el mejor desarrollo de las variables no sanitarias, seguido de MSF y USAID. Médicos sin fronteras muestra un grado de desarrollo de las variables sanitarias del 97,3% seguido de ACNUR (94,7%, USAID y UNICEF (92,1%. Conclusiones: Se ha encontrado que ACNUR tiene la propuesta más integral y Oficina de Coordinación de Asuntos Humanitarios de Naciones Unidas la más discreta. Existe una tendencia general a desarrollar y unificar los indicadores de salud, mientras que otros aspectos no se desarrollan.

  8. Environmental control of plant nuclear gene expression by chloroplast redox signals

    Directory of Open Access Journals (Sweden)

    Jeannette ePfalz

    2012-11-01

    Full Text Available Plant photosynthesis takes place in specialised cell organelles, the chloroplasts, which perform all essential steps of this process. The proteins involved in photosynthesis are encoded by genes located on the plastid and nuclear genomes. Proper function and regulation of light harvesting and energy fixation thus requires a tight coordination of the gene expression machineries in the two genetic compartments. This is achieved by a bi-directional exchange of information between nucleus and plastids. Signals emerging from plastids report the functional and developmental state of the organelle to the nucleus and initiate distinct nuclear gene expression profiles, which trigger responses that support or improve plastid functions. Recent research indicated that this signalling is absolutely essential for plant growth and development. Reduction/oxidation (redox signals from photosynthesis are key players in this information network since they do report functional disturbances in photosynthesis, the primary energy source of plants. Such disturbances are caused by environmental fluctuations for instance in illumination, temperature or water availability. These environmental changes affect the linear electron flow of photosynthesis and result in changes of the redox state of the components involved (e.g. the plastoquinone pool or coupled to it (e.g. the thioredoxin pool. Thus, the changes in redox state directly reflect the environmental impact and serve as immediate plastidial signals to the nucleus. The triggered responses range from counterbalancing reactions within the physiological range up to severe stress responses including cell death. This review focuses on physiological redox signals from photosynthetic electron transport, their relation to the environment, potential transduction pathways to the nucleus and their impact on nuclear gene expression.

  9. Basis for and practical methods of controlling painting activities at the Sequoyah Nuclear Plant

    Energy Technology Data Exchange (ETDEWEB)

    Campbell, R.R. [Tennessee Valley Authority, Chattanooga, TN (United States)

    1997-08-01

    Sequoyah Nuclear Plant (SQN) follows the guidance presented in Regulatory Guide (R.G.) 1.52, {open_quotes}Design, Testing, and Maintenance Criteria for Atmospheric Cleanup System Air Filtration and Adsorption System Units of Light-Water-Cooled Nuclear Power Plants{close_quotes} in protecting its charcoal filter trains from the effects of painting and other chemical releases. SQN, as well as other nuclear facilities around the country, have the problem of how to address the issue of protection of Engineered Safety Feature (ESF) filter systems from degradation due to communication with airborne hydrocarbons (i.e., primarily paints and solvents). R.G. 1.52 (and a similar statement from R.G. 1.140) states in part,{open_quotes}Testing should be performed ... following painting, fire, or chemical release in any ventilation zone communicating with the system...,{close_quotes} and requires that a test be performed upon any kind of painting or chemical release. This is considered overly restrictive if the activity is minor and in a location remote from the charcoal filters. Charcoal filters used in air cleaning systems are required to filter out radioactive iodine from an airstream before its release from the plant to the environment. Charcoal filters will age with time because of their ability to adsorb many different types of material. This aging affects the charcoal by lowering its iodine retention efficiency, and therefore the charcoal needs to be protected from the effects of chemicals such as paint fumes. 14 refs., 3 tabs.

  10. Archaeometric analysis of Roman bronze coins from the Magna Mater temple using solid-state voltammetry and electrochemical impedance spectroscopy.

    Science.gov (United States)

    Di Turo, Francesca; Montoya, Noemí; Piquero-Cilla, Joan; De Vito, Caterina; Coletti, Fulvio; Favero, Gabriele; Doménech-Carbó, Antonio

    2017-02-22

    Voltammetry of microparticles (VMP) and electrochemical impedance spectroscopy (EIS) techniques, complemented by SEM-EDX and Raman spectroscopy, were applied to a set of 15 Roman bronze coins and one Tessera from the temple of Magna Mater (Rome, Italy). The archaeological site, dated back between the second half and the end of the 4th century A.D., presented a complicated stratigraphic context. Characteristic voltammetric patterns for cuprite and tenorite for sub-microsamples of the corrosion layers of the coins deposited onto graphite electrodes in contact with 0.10 M HClO4 aqueous solution yielded a grouping of the coins into three main groups. This grouping was confirmed and refined using EIS experiments of the coins immersed in air-saturated mineral water using the reduction of dissolved oxygen as a redox probe. The electrochemical grouping of coins corroborated the complex stratigraphy of the archaeological site and, above all, the reuse of the coins during the later periods due to the economic issues related to the fall of the Roman Empire. Copyright © 2016 Elsevier B.V. All rights reserved.

  11. Intrauterine growth and intelligence within sibling pairs: findings from the Mater-University study of pregnancy and its outcomes.

    Science.gov (United States)

    Lawlor, Debbie A; Bor, William; O'Callaghan, Michael J; Williams, Gail M; Najman, Jake M

    2005-04-01

    To examine the association between intrauterine growth and intelligence. Population based birth cohort study of sibling pairs born within a maximum of three years of each other. Mater-University women and children's hospital, Brisbane, Australia. 235 (470 children) sibling pairs. Among one randomly selected sibling from each pair verbal comprehension at age 5, general intelligence at age 14, and reading ability at age 14 increased linearly with increasing gestational age and sex standardised birth weight z scores. With adjustment for maternal age, race, and smoking during pregnancy, birth order, family income, and parental education the associations with verbal comprehension at age 5 and general intelligence at age 14 remained, whereas the association with reading ability at age 14 was attenuated to the null. Within sibling pairs, differences in intrauterine growth were positively associated with differences in verbal comprehension at age 5 (test score difference per one unit difference in birth weight z score = 1.52 (0.11 to 3.26)) and general intelligence at age 14 (1.09 (0.01 to 2.18)), but not with reading ability at age 14. Socioeconomic position or other fixed maternal characteristics do not seem to explain the positive association between intrauterine growth and childhood intelligence.

  12. Nuclear Medicine

    Science.gov (United States)

    ... Parents/Teachers Resource Links for Students Glossary Nuclear Medicine What is nuclear medicine? What are radioactive tracers? ... funded researchers advancing nuclear medicine? What is nuclear medicine? Nuclear medicine is a medical specialty that uses ...

  13. Evaluation of training programs and entry-level qualifications for nuclear-power-plant control-room personnel based on the systems approach to training

    Energy Technology Data Exchange (ETDEWEB)

    Haas, P M; Selby, D L; Hanley, M J; Mercer, R T

    1983-09-01

    This report summarizes results of research sponsored by the US Nuclear Regulatory Commission (NRC) Office of Nuclear Regulatory Research to initiate the use of the Systems Approach to Training in the evaluation of training programs and entry level qualifications for nuclear power plant (NPP) personnel. Variables (performance shaping factors) of potential importance to personnel selection and training are identified, and research to more rigorously define an operationally useful taxonomy of those variables is recommended. A high-level model of the Systems Approach to Training for use in the nuclear industry, which could serve as a model for NRC evaluation of industry programs, is presented. The model is consistent with current publically stated NRC policy, with the approach being followed by the Institute for Nuclear Power Operations, and with current training technology. Checklists to be used by NRC evaluators to assess training programs for NPP control-room personnel are proposed which are based on this model.

  14. The development of advanced robotic technology. A study on the tele-existence and intelligent control of a robot system for nuclear power plants

    Energy Technology Data Exchange (ETDEWEB)

    Chung, Myung Jin; Byun, Jueng Nam; Kim, Jong Hwan; Lee, Ju Jang; Bang, Seok Won; Chu, Gil Hwan; Park, Jong Cheol; Choi, Jong Seok; Yang, Jung Min; Hong, Sun Ki [Korea Advanced Institute of Science and Technology, Taejon (Korea, Republic of)

    1995-07-01

    To increase the efficiency of human intelligence it is required to develop an intelligent monitoring and system. In this research, we develop intelligent control methods related with tele-operation, tele-existence, real-time control technique, and intelligent control technique. Those are key techniques in tele-operation, especially for the repair and maintenance of nuclear power plants. The objective of this project is to develop of the tele-existence and intelligent control system for a robot used in the nuclear power plants. (author). 20 refs.

  15. Network communication for remote technology and NDT controls on current nuclear power plants

    Energy Technology Data Exchange (ETDEWEB)

    Capitaine, A. [Electricite de France, 92 - Clamart (France). Service Etudes et Projets Thermiques et Nucleaires

    2001-07-01

    Among the most important targets for ''UTILITIES'' are to increase nuclear power plant availability and reduce the workers dosimetry. A possible way to reach these targets is to reduce the duration of the refueling period and to limit the number of operators in the work areas It is necessary to use remote technology and to provide much equipment to support the main activities during refueling. Remote technology is a possible solution to remove operators from the maintenance area. The main activities concerned are the NDT inspection on the primary components and fuel handling system. Recent progress on remote technology made by the electronic industry and network communication has increased their capacities. It is easier now to use them, and more and more people are familiar with these technologies. Internet, manufacturing, supervision, and surgery use these technologies. Now it seems appropriate to examine these technologies for current maintenance in nuclear plants. Remote technologies and communication network can help to solve current difficulties in the maintenance field and dosimetry limits. For a long time, many people thought that the cost and the difficulty of applying new technologies would be not extremely expensive, but this is no longer the case. Now with the first feed back we can show that these technologies are a good answer for increased availability and reduction of dosimetry. (author)

  16. SMRT repression of nuclear receptors controls the adipogenic set point and metabolic homeostasis.

    Science.gov (United States)

    Nofsinger, Russell R; Li, Pingping; Hong, Suk-Hyun; Jonker, Johan W; Barish, Grant D; Ying, Hao; Cheng, Sheue-Yann; Leblanc, Mathias; Xu, Wei; Pei, Liming; Kang, Yeon-Joo; Nelson, Michael; Downes, Michael; Yu, Ruth T; Olefsky, Jerrold M; Lee, Chih-Hao; Evans, Ronald M

    2008-12-16

    The nuclear receptor corepressor, silencing mediator of retinoid and thyroid hormone receptors (SMRT), is recruited by a plethora of transcription factors to mediate lineage and signal-dependent transcriptional repression. We generated a knockin mutation in the receptor interaction domain (RID) of SMRT (SMRT(mRID)) that solely disrupts its interaction with nuclear hormone receptors (NHRs). SMRT(mRID) mice are viable and exhibit no gross developmental abnormalities, demonstrating that the reported lethality of SMRT knockouts is determined by non-NHR transcription factors. However, SMRT(mRID) mice exhibit widespread metabolic defects including reduced respiration, altered insulin sensitivity, and 70% increased adiposity. The latter phenotype is illustrated by the observation that SMRT(mRID)-derived MEFs display a dramatically increased adipogenic capacity and accelerated differentiation rate. Collectively, our results demonstrate that SMRT-RID-dependent repression is a key determinant of the adipogenic set point as well as an integrator of glucose metabolism and whole-body metabolic homeostasis.

  17. Amplification of Nicotiana sylvestris mitochondrial subgenomes is under nuclear control and is associated with phenotypic changes.

    Science.gov (United States)

    Albert, Béatrice; Lelandais, Christine; Pla, Magali; Leuret, Corine; Vitart, Véronique; Mathieu, Chantal; Sihachakr, Darasinh; Godelle, Bernard; De Paepe, Rosine

    2003-01-01

    We have previously shown the presence in a Nicotiana sylvestris protoplast-derived plant of both a nuclear mutation conferring male sterility (ms4) and a mtDNA reorganisation, named U, characterised by the amplification of substoichiometric mtDNA fragments generated by recombination in the parent T mtDNA. Here we show by physical mapping that the recombining repeats are in direct orientation, thus generating two subgenomes both of which are amplified in the U organisation to the detriment of the parent molecule, and are maintained through sexual reproduction. The nuclear ms4 mutation is likely to have play a role in the shift in mitochondrial molecule equilibrium, as higher levels of recombinant fragments were present in protoplast-derived T calli carrying the ms4 allele than in wild type calli or leaves. The MS4 gene could then lead to conflictual situation. However, subgenomic molecules were counter-selected during the regeneration process, suggesting the existence of different selective pressures in differentiated and non-differentiated cells. The U organisation is associated with higher stem height and late flowering, characters that may not be neutral from a selection point of view. The U equilibrium is an unusual example of sudden mtDNA reorganisation, without obvious differences in genetic information and with only a limited phenotypic impact.

  18. Evaluation of ecological interface design for nuclear process control: situation awareness effects.

    Science.gov (United States)

    Burns, Catherine M; Skraaning, Gyrd; Jamieson, Greg A; Lau, Nathan; Kwok, Jordanna; Welch, Robin; Andresen, Gisle

    2008-08-01

    We determine whether an ecological interface display for nuclear power plant operations supports improved situation awareness over traditional and user-centered displays in a realistic environment. Ecological interface design (EID) has not yet been fully evaluated with real operators facing realistic scenarios. Ecological displays were evaluated alongside traditional and user-centered "advanced" displays in a full-scope nuclear power plant simulation. Licensed plant operators used the displays in realistic scenarios that either had procedural support or did not have procedural support. All three displays were evaluated for their ability to support operator situation awareness. A significant three-way interaction effect was observed on two independent measures of situation awareness. For both measures, ecological displays improved situation awareness in scenarios that did not have procedural support, primarily in the detection phases of those scenarios. No other pronounced effects appeared across both measures. The observed improvement was sufficiently large to suggest that EID could improve situation awareness in situations where procedures are unavailable. However, the EID displays did not lead to improved situation awareness in the other conditions of the evaluation, and participants using these displays occasionally underperformed on single measures of situation awareness. This suggests that the approach requires further development, particularly in integrating EID with procedural support. This research has important findings for the ongoing development of the EID approach, the design of industrial operator displays, and design to support situation awareness.

  19. Baseline Study Methodology for Future Phases of Research on Nuclear Power Plant Control Room Technologies

    Energy Technology Data Exchange (ETDEWEB)

    Le Blanc, Katya Lee [Idaho National Lab. (INL), Idaho Falls, ID (United States); Bower, Gordon Ross [Idaho National Lab. (INL), Idaho Falls, ID (United States); Hill, Rachael Ann [Idaho National Lab. (INL), Idaho Falls, ID (United States); Spielman, Zachary Alexander [Idaho National Lab. (INL), Idaho Falls, ID (United States); Rice, Brandon Charles [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2016-07-01

    In order to provide a basis for industry adoption of advanced technologies, the Control Room Upgrades Benefits Research Project will investigate the benefits of including advanced technologies as part of control room modernization This report describes the background, methodology, and research plan for the first in a series of full-scale studies to test the effects of advanced technology in NPP control rooms. This study will test the effect of Advanced Overview Displays in the partner Utility’s control room simulator

  20. Emotional learning based intelligent controller for a PWR nuclear reactor core during load following operation

    Energy Technology Data Exchange (ETDEWEB)

    Khorramabadi, Sima Seidi [Department of Mechanical Engineering, Sharif University of Technology, P.O. Box 11365-9567, Tehran (Iran, Islamic Republic of)], E-mail: sima_s_kh@yahoo.com; Boroushaki, Mehrdad [Department of Mechanical Engineering, Sharif University of Technology, P.O. Box 11365-9567, Tehran (Iran, Islamic Republic of); Lucas, Caro [Center of Excellence for Control and Intelligent Processing, Department of Electrical and Computer Engineering, University of Tehran, and School of Intelligent Systems, IPM, P.O. Box 14395-515, Tehran (Iran, Islamic Republic of)

    2008-11-15

    The design and evaluation of a novel approach to reactor core power control based on emotional learning is described. The controller includes a neuro-fuzzy system with power error and its derivative as inputs. A fuzzy critic evaluates the present situation, and provides the emotional signal (stress). The controller modifies its characteristics so that the critic's stress is reduced. Simulation results show that the controller has good convergence and performance robustness characteristics over a wide range of operational parameters.

  1. The Future Nuclear Arms Control Agenda and Its Potential Implications for the Air Force

    Science.gov (United States)

    2015-08-01

    contributions to U.S. arms control decision-making; and areas for Air Force “ homework ” to prepare for and engage effectively in an evolving arms control...judgments about bottom-line implications for the Air Force. There also is a quick reprise of the Air Force “ homework ” across the arms control domains...deployments closer to Russia’s borders; the availability of credible military alternatives to carry out missions that might be executed by banned

  2. A Mathematical Model for the Removal of Organic Mater in Stabilization Ponds

    Directory of Open Access Journals (Sweden)

    Waldir Medri

    2002-03-01

    Full Text Available This work presents an application to systemize the construction of ponds systems for treatment of domestic sewage. It consisted of two anaerobic ponds operated in parallel during May/97 to April/99. These were connected in series with a chicaned facultative pond. The treatment system was controlled with samples collected from the crude sewage (compound sample, in the affluents and effluents of the ponds and along the flux of the anaerobic and facultative ponds. The following parameters were analyzed: pH, Biochemical Oxygen Demand, Chemical Oxygen Demand, Total Solids, Sedimentable Solids, Total Coliforms, Oxygen Consumed in Acid Medium (OCAM and temperature.Este trabalho apresenta uma aplicação para sistematizar a construção de sistemas de lagoas para tratamento de esgoto doméstico. O sistema consiste de duas lagoas anaeróbias operando em paralelo durante o período de maio/97 até abril/99. Estas lagoas eram conectadas em série com uma lagoa facultativa chicaneada. O sistema de tratamento foi monitorado com amostra coletadas no esgoto bruto (amostra composta, nos afluentes e efluentes das lagoas e ao longo dos fluxos das lagoas anaeróbia e facultativa. Os seguintes parâmetros foram analisados: pH, Demanda Bioquímica de Oxigênio (DBO, Demanda Química de Oxigênio (DQO, Sólidos Totais (ST, Sólidos Sedimentáveis (SS, Coliformes Totais (CT, Oxigênio Consumido em Meio Ácido (OCMA e Temperatura.

  3. Evaluation of the Nuclear Medicine facilities in Minas Gerais state: quality control program of equipment; Avaliacao dos servicos de Medicina Nuclear do estado de Minas Gerais: programa de controle de qualidade dos equipamentos

    Energy Technology Data Exchange (ETDEWEB)

    Kubo, Tadeu Takao Almodovar; Biancardi, Rodrigo; Rocha, Adriana Marcia Guimaraes; Ferreira, Denia Romao; Silva, Franciele Aquiles Anjos; Assuncao, Jonathan Buenos Aires; Alves, Ederson Henrique; Almeida, Ana Flavia Batista; Alves, Nathalia Fernandes; Xavier, Faber Henrique Zacarias; Gontijo, Rodrigo Modesto Gadelha; Mamede, Marcelo, E-mail: mamede.mm@gmail.com [Centro de Desenvolvimento da Tecnologia Nuclear (CDTN/CNEN), Belo Horizonte, MG (Brazil); Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG (Brazil). Departamento Anatomia e Imagem

    2017-11-01

    With the reformulation of the CNEN-NN-3.05 standard in December 2013, Brazil's Nuclear Medicine (NMS) services have to perform a greater number of quality controls for SPECT and PET equipment. However, little is known about the reality of the quality control programs of these services regarding the application of the new standard. Thus, in this context, the objective of the present study was to evaluate the quality control program of MNSs in the state of Minas Gerais. All NMSs in the state of Minas Gerais were invited to participate in the project. Of these, 34.48% (20 facilities) agreed to participate in the project, 50.00% (29 facilities) did not respond to the invitation and 15.52%(9 facilities) declined their participation. Thus, as of November 2015, 20 SPECT and 2 PET/CT equipment were evaluated for the performance of the quality control tests recommended by the new CNEN standard. The phantoms required for the evaluation came from the Laboratory of Dosimetry and Quality Control of UFMG. Even with the deadlines set by CNEN for the implementation of the quality control program in the NMSs, more than 50% of the evaluated services did not implement the quality controls, and the absence of specific phantoms is the main reason for the failure. Among the problems found in the installations, the most critical were: collimators with no conditions of use in the clinical routine, linearity problems of the evaluated image and values of image uniformity superior to the limits of acceptance. Problems in the uniformity and linearity of the image found directly impacted the performance of other tests, such as spatial resolution, SPECT performance, among others. In a general way, the NMSs in the state of Minas Gerais evaluated with the present study are in clinical feasible conditions. (author)

  4. Electric-stepping-motor tests for a control-drum actuator of a nuclear reactor

    Science.gov (United States)

    Kieffer, A. W.

    1972-01-01

    Experimental tests were conducted on two stepping motors for application as reactor control-drum actuators. Various control-drum loads with frictional resistances ranging from approximately zero to 40 N-m and inertias ranging from zero to 0.424 kg-sq m were tested.

  5. The transcription factor Prep1 controls hepatic insulin sensitivity and gluconeogenesis by targeting nuclear localization of FOXO1.

    Science.gov (United States)

    Kulebyakin, Konstantin; Penkov, Dmitry; Blasi, Francesco; Akopyan, Zhanna; Tkachuk, Vsevolod

    2016-12-02

    Liver plays a key role in controlling body carbohydrate homeostasis by switching between accumulation and production of glucose and this way maintaining constant level of glucose in blood. Increased blood glucose level triggers release of insulin from pancreatic β-cells. Insulin represses hepatic glucose production and increases glucose accumulation. Insulin resistance is the main cause of type 2 diabetes and hyperglycemia. Currently thiazolidinediones (TZDs) targeting transcriptional factor PPARγ are used as insulin sensitizers for treating patients with type 2 diabetes. However, TZDs are reported to be associated with cardiovascular and liver problems and stimulate obesity. Thus, it is necessary to search new approaches to improve insulin sensitivity. A promising candidate is transcriptional factor Prep1, as it was shown earlier it could affect insulin sensitivity in variety of insulin-sensitive tissues. The aim of the present study was to evaluate a possible involvement of transcriptional factor Prep1 in control of hepatic glucose accumulation and production. We created mice with liver-specific Prep1 knockout and discovered that hepatocytes derived from these mice are much more sensitive to insulin, comparing to their WT littermates. Incubation of these cells with 100 nM insulin results in almost complete inhibition of gluconeogenesis, while in WT cells this repression is only partial. However, Prep1 doesn't affect gluconeogenesis in the absence of insulin. Also, we observed that nuclear content of gluconeogenic transcription factor FOXO1 was greatly reduced in Prep1 knockout hepatocytes. These findings suggest that Prep1 may control hepatic insulin sensitivity by targeting FOXO1 nuclear stability. Copyright © 2016 Elsevier Inc. All rights reserved.

  6. Nuclear LSm8 affects number of cytoplasmic processing bodies via controlling cellular distribution of Like-Sm proteins.

    Science.gov (United States)

    Novotny, Ivan; Podolská, Katerina; Blazíková, Michaela; Valásek, Leos Shivaya; Svoboda, Petr; Stanek, David

    2012-10-01

    Processing bodies (P-bodies) are dynamic cytoplasmic structures involved in mRNA degradation, but the mechanism that governs their formation is poorly understood. In this paper, we address a role of Like-Sm (LSm) proteins in formation of P-bodies and provide evidence that depletion of nuclear LSm8 increases the number of P-bodies, while LSm8 overexpression leads to P-body loss. We show that LSm8 knockdown causes relocalization of LSm4 and LSm6 proteins to the cytoplasm and suggest that LSm8 controls nuclear accumulation of all LSm2-7 proteins. We propose a model in which redistribution of LSm2-7 to the cytoplasm creates new binding sites for other P-body components and nucleates new, microscopically visible structures. The model is supported by prolonged residence of two P-body proteins, DDX6 and Ago2, in P-bodies after LSm8 depletion, which indicates stronger interactions between these proteins and P-bodies. Finally, an increased number of P-bodies has negligible effects on microRNA-mediated translation repression and nonsense mediated decay, further supporting the view that the function of proteins localized in P-bodies is independent of visible P-bodies.

  7. Nuclear disarmament verification

    Energy Technology Data Exchange (ETDEWEB)

    DeVolpi, A.

    1993-12-31

    Arms control treaties, unilateral actions, and cooperative activities -- reflecting the defusing of East-West tensions -- are causing nuclear weapons to be disarmed and dismantled worldwide. In order to provide for future reductions and to build confidence in the permanency of this disarmament, verification procedures and technologies would play an important role. This paper outlines arms-control objectives, treaty organization, and actions that could be undertaken. For the purposes of this Workshop on Verification, nuclear disarmament has been divided into five topical subareas: Converting nuclear-weapons production complexes, Eliminating and monitoring nuclear-weapons delivery systems, Disabling and destroying nuclear warheads, Demilitarizing or non-military utilization of special nuclear materials, and Inhibiting nuclear arms in non-nuclear-weapons states. This paper concludes with an overview of potential methods for verification.

  8. Improvement of automatic control systems of high-power turbines of PAO tubroatom for nuclear power plants

    Science.gov (United States)

    Shvetsov, V. L.; Babaev, I. N.

    2017-09-01

    The main technical solutions applied by PAO Turboatom used as the compensatory measures at the increase of the period of nonstop operation of nuclear power plants' (NPP) turbines with VVER-1000 type reactors up to 18 months are (1) replacing the standard hydraulic speed controller with an electronic one, (2) introduction of overclocking protection, (3) modernization of units of stop-control valves of high pressures, (4) installation of locking dampers on the receiver tubes of turbines of the first and second modification, and (5) improving the quality of repairs by reviewing the requirements for their implementation. The introduction of complex diagnostics of a control system on the basis of automatic treatment of results of registration of working parameters of the turbine is allocated as a separate prospective direction. Using an electronic controller of speed makes it possible to simplify the procedure of its inclusion in work at the failure of an electro-hydraulic system of control and vice versa. The regimes of maintaining the turbine rotor speed, steam pressure on the outlet of turbine, and the positions of main servomotors were introduced into the functions of the electronic controller. An electronic controller of speed includes its own electro-hydraulic transducer, turbine rotor speed sensor, and sensors of the position of main servomotors. Into the functions of electro- hydraulic control system and electronic speed controller, the function of overclocking protection, which determines the formation of commands for stopping the turbine at the exceeding of both the defined level of rotation speed and the defined combination of achieved rotation speed and angular acceleration of rotor, was introduced. To simplify the correction of forces acting on the control valve cups, the design of the cups was changed, and it has the profiled inserts. The solutions proposed were implemented on K-1100-60/1500-2M turbines of Rostov NPP. From the composition of control system

  9. The Nuclear Oncogene SET Controls DNA Repair by KAP1 and HP1 Retention to Chromatin

    Directory of Open Access Journals (Sweden)

    Alkmini Kalousi

    2015-04-01

    Full Text Available Cells experience damage from exogenous and endogenous sources that endanger genome stability. Several cellular pathways have evolved to detect DNA damage and mediate its repair. Although many proteins have been implicated in these processes, only recent studies have revealed how they operate in the context of high-ordered chromatin structure. Here, we identify the nuclear oncogene SET (I2PP2A as a modulator of DNA damage response (DDR and repair in chromatin surrounding double-strand breaks (DSBs. We demonstrate that depletion of SET increases DDR and survival in the presence of radiomimetic drugs, while overexpression of SET impairs DDR and homologous recombination (HR-mediated DNA repair. SET interacts with the Kruppel-associated box (KRAB-associated co-repressor KAP1, and its overexpression results in the sustained retention of KAP1 and Heterochromatin protein 1 (HP1 on chromatin. Our results are consistent with a model in which SET-mediated chromatin compaction triggers an inhibition of DNA end resection and HR.

  10. The falsification of Chiral Nuclear Forces

    Science.gov (United States)

    Ruiz Arriola, E.; Amaro, J. E.; Navarro Perez, R.

    2017-03-01

    Predictive power in theoretical nuclear physics has been a major concern in the study of nuclear structure and reactions. The Effective Field Theory (EFT) based on chiral expansions provides a model independent hierarchy for many body forces at long distances but their predictive power may be undermined by the regularization scheme dependence induced by the counterterms and encoding the short distances dynamics which seem to dominate the uncertainties. We analyze several examples including zero energy NN scattering or perturbative counterterm-free peripheral scattering where one would expect these methods to work best and unveil relevant systematic discrepancies when a fair comparison to the Granada-2013 NN-database and partial wave analysis (PWA) is undertaken. Work supported by Spanish Ministerio de Economia y Competitividad and European FEDER funds (grant FIS2014-59386-P), the Agencia de Innovacion y Desarrollo de Andalucia (grant No. FQM225), the U.S. Department of Energy by Lawrence Livermore National Laboratory under Contract No. DE-AC52-07NA27344, U.S. Department of Energy, Office of Science, Office of Nuclear Physics under Award No. DE-SC0008511 (NUCLEI SciDAC Collaboration)

  11. Investigation on the use digital controls instead of PID analog controls in the level control of steam generators of nuclear power PWR; Investigacao sobre o uso de controladores digitais em substituicao aos controladores analogicos PID para o controle de nivel de geradores de vapor de centrais nucleares PWR

    Energy Technology Data Exchange (ETDEWEB)

    Alvarenga, Marco Antonio Bayout

    2012-07-01

    The aim of this study is to identify current alternatives for the implementation of digital controllers in the level control of steam generators of nuclear power PWR (Pressurized Water Reaetor). It is intended to identify the types of digital controls that are available from the theoretical and conceptual viewpoints for this purpose. We investigate the advantages and disadvantages of each controller model. From this assessment are pointed the most suitable models in hierarchical scale. This evaluation also serves to suggest possible types of control installation as a whole, where the level control of the steam generators becomes just one of many controls that are part of the plant. In this case, the use of digital controls allows the non-linear and multivariable treatment which is characteristic of complex systems, such as the nuclear power generation. The treatment of nonlinearities and multivariable aspects allows a more detailed study of the stability of these plants when they are subject to transients or several accidents, such as the case of losing external power of transients. In the specific case of steam generators, the instabilities result from the emergence of the shrink and swell phenomenas, depending on the load variations of thermonuclear plant. The application of several types and digital controllers, considering these inherent characteristics of the level control of steam generators, allows to infer which types of controllers are more appropriate to treat instabilities of this type and to make conjectures in its use for the cases of more complex instabilities, considering the integration of all nucleus-plant controls.

  12. AN ANALYSIS OF TECHNICAL SECURITY CONTROL REQUIREMENTS FOR DIGITAL I&C SYSTEMS IN NUCLEAR POWER PLANTS

    Directory of Open Access Journals (Sweden)

    JAE-GU SONG

    2013-10-01

    Full Text Available Instrumentation and control systems in nuclear power plants have been digitalized for the purpose of maintenance and precise operation. This digitalization, however, brings out issues related to cyber security. In the most recent past, international standard organizations, regulatory institutes, and research institutes have performed a number of studies addressing these systems cyber security. In order to provide information helpful to the system designers in their application of cyber security for the systems, this paper presents methods and considerations to define attack vectors in a target system, to review and select the requirements in the Regulatory Guide 5.71, and to integrate the results to identify applicable technical security control requirements. In this study, attack vectors are analyzed through the vulnerability analyses and penetration tests with a simplified safety system, and the elements of critical digital assets acting as attack vectors are identified. Among the security control requirements listed in Appendices B and C to Regulatory Guide 5.71, those that should be implemented into the systems are selected and classified in groups of technical security control requirements using the results of the attack vector analysis. For the attack vector elements of critical digital assets, all the technical security control requirements are evaluated to determine whether they are applicable and effective, and considerations in this evaluation are also discussed. The technical security control requirements in three important categories of access control, monitoring and logging, and encryption are derived and grouped according to the elements of attack vectors as results for the sample safety system.

  13. A fuzzy rule base for the control of a nuclear reactor

    Energy Technology Data Exchange (ETDEWEB)

    Si-Fodil, M.; Guely, F.; Siarry, P. [Ecole Centrale de Paris, 92 - Chatenay-Malabry (France); Tyran, J.L. [Electricite de France (EDF), 78 - Chatou (France). Direction des Etudes et Recherches

    1998-12-31

    This paper presents the development of a real time fuzzy controller for the power axial-offset and the R control rods insertion in a pressurized water reactor (PWR). Fundamentally two parameters are concerned by this task : the power axial-offset and rods position. The focus of this study is the automation of the control of the power axial-offset by adding soluble boron, and by minimizing the flows through the water pump. Water or boron is injected into the reactor. It is also important to take into consideration the liquid waste volume. Our aim is to run the fuzzy controller at least as efficient as an expert operator. The system has been implemented in simulation using the Matlab-Simulink on a Sun workstation. (authors) 6 refs.

  14. 77 FR 43506 - DoD Unclassified Controlled Nuclear Information (UCNI)

    Science.gov (United States)

    2012-07-25

    ...) Information. Any fact or concept, regardless of the physical form or characteristics of the medium on or in..., and control of the Under Secretary of Defense for Acquisition, Technology, and Logistics, shall: (1...

  15. 76 FR 22849 - DoD Unclassified Controlled Nuclear Information (UCNI)

    Science.gov (United States)

    2011-04-25

    ...) Information. Any fact or concept, regardless of the physical form or characteristics of the medium on or in..., and control of the Under Secretary of Defense for Acquisition, Technology and Logistics, shall: (1...

  16. Psychological factors of professional success of nuclear power plant main control room operators

    OpenAIRE

    Kosenkov A.A.

    2014-01-01

    Aim: to conduct a comparative analysis of the psychological characteristics of the most and least successful main control room operators. Material and Methods. Two NPP staff groups: the most and least successful main control room operators, who worked in routine operating conditions, were surveyed. Expert evaluation method has been applied to identify the groups. The subjects were administered the Minnesota Multiphasic Personality Inventory (MMPI), Cattell's Sixteen Personality Factor Questio...

  17. The affective bases of team performance during nonroutine events: The case of nuclear power plant control room crews

    Science.gov (United States)

    Kaplan, Seth A.

    By conceiving of teams' nonroutine performance as a series of coping responses, this paper examines how crewmembers' positive and negative affectivity (PA, NA) impact individual behaviors and team processes. A theoretical model is developed in which trait affect's influence is predicted to vary depending on the nature of the task, the level of analysis, and the timing of behaviors. The model is empirically tested using coded behaviors of 75 nuclear power plant control room operators, composing 17 crews, who engage in a high-fidelity training simulation. Results using random coefficient modeling were mixed, but generally failed to support the study hypotheses. Discussion focuses on the potential benefits of NA in organizations and on the limitations of the current study context.

  18. Virtual Visit to the ATLAS Control Room during Researchers Night by Institute of Nuclear Physics Polish Academy of Sciences, Cracow

    CERN Multimedia

    ATLAS Experiment

    2012-01-01

    We invite our "6-th Ma?opolska Researchers Night" guests for Virtual Visits in ATLAS Control Room. They could ask Polish scientists and experts during a lecture "How a mass is created - the Higgs boson discovery" to be given by dr Anna Kaczmarska. "Ma?opolska Researchers Night" is a part of European Researchers Night events to be held in more than 200 cities. Institute of Nuclear Physics Polish Academy of Sciences invites Cracow citizens and tourists visiting our town to its laboratories and to the "Science Garden" formed, especially for this event, in front of the main building. Visitors will have an unique opportunity to discuss science problems with researches and students. Wide range of demonstrations of interesting activities performed in our institute will be presented, these include among others: - AIC 144 Cyclotron with hadrons' therapy facility for eye treatment - Dosimetry and environmental pollution monitoring - Large Hadron Collider experiments - Van de Graff linear accelerator with proton micro b...

  19. Investigation of the impact of main control room digitalization on operators cognitive reliability in nuclear power plants.

    Science.gov (United States)

    Zhou, Yong; Mu, Haiying; Jiang, Jianjun; Zhang, Li

    2012-01-01

    Currently, there is a trend in nuclear power plants (NPPs) toward introducing digital and computer technologies into main control rooms (MCRs). Safe generation of electric power in NPPs requires reliable performance of cognitive tasks such as fault detection, diagnosis, and response planning. The digitalization of MCRs has dramatically changed the whole operating environment, and the ways operators interact with the plant systems. If the design and implementation of the digital technology is incompatible with operators' cognitive characteristics, it may have negative effects on operators' cognitive reliability. Firstly, on the basis of three essential prerequisites for successful cognitive tasks, a causal model is constructed to reveal the typical human performance issues arising from digitalization. The cognitive mechanisms which they impact cognitive reliability are analyzed in detail. Then, Bayesian inference is used to quantify and prioritize the influences of these factors. It suggests that interface management and unbalanced workload distribution have more significant impacts on operators' cognitive reliability.

  20. LA AGENCIA DE LA NIÑA Y EL NIÑO EN LA CONDICIÓN PRE-CIUDADANA AGENCY (CHILDHOOD IN THE PRE-CITIZEN CONDITION

    Directory of Open Access Journals (Sweden)

    González Coto, Marcela

    2012-05-01

    Full Text Available Resumen: El presente ensayo se deriva del trabajo que recientemente han desarrollado la Fundación PANIAMOR y la Dirección General del Programa CEN-CINAI del Ministerio de Salud, sobre la formación ciudadana de los niños y las niñas costarricenses en la primera infancia. Las acciones conjuntas se han enfocado en la capacidad de agencia de los niños y las niñas, entendida como la disposición para explorar, reflexionar, actuar y valorarse en sus entornos como sujetos políticos. Para este fin, en este ensayo se lleva a cabo un análisis crítico de los modelos ideológicos y culturales que, en la sociedad contemporánea, legitiman y fomentan la condición de “pre-ciudadanía” de la infancia, mermando su desempeño, presente y futuro, como ciudadanos plenos de la sociedad. El análisis se sustenta en materiales diversos, de distintos orígenes, todos relativos a las condiciones actuales de la infancia y las formas como se restringen estas capacidades de agencia. El ensayo también aborda las dificultades y obstáculos que enfrenta un replanteamiento de las relaciones entre adultos y niños. También se documentan los esfuerzos recientes, tanto locales como internacionales, para crear marcos alternativos desde los cuales replantear la relación institucional entre unos y otros. Como principal resultado del ensayo, se delinean un conjunto de directrices, con expresión curricular, que pueden sustentar el desarrollo de las capacidades de agencia infantil con una manifestación directa en la niñez ciudadana, la cual, se plantea, se articula en tres dimensiones o ejes de desarrollo (la responsabilidad, la autonomía y el pensamiento complejo.Abstract: This essay is derived from the works that have recently developed the PANIAMOR Foundation and the General Board of Directors of the CEN-CINAI Program of the National Ministry of Health, on the civic education of Costa Rican children in early childhood. Joint activities have focused on the

  1. A monitoring network of the radioactive releases control due to Garigliano nuclear power plant decommissioning

    Energy Technology Data Exchange (ETDEWEB)

    Sabbarese, C.; Esposito, A.M.; Visciano, L.; D' onofrio, A.; Lubritto, C.; Terrasi, F. [Napoli Univ., Dipt. di Scienze Ambientali (Italy); Roca, V. [Napoli Univ. Federico 2, Dipt. di Scienze Fisiche (Italy); Alfieri, S.; Migliore, G. [Centrale Nucleare del Garigliano, SoGIN, Sessa Aurunca (Caserta) (Italy)

    2004-07-01

    The present study is the second part of a program of characterization of the site surrounding the SoGIN Garigliano Nuclear Power Plant (South Italy). The operation of the reactor was stopped in 1978 and it is currently involved in decommissioning activities. In the first phase of the project, the reference groups of the population were established on the basis of a socio-economical study of the site. The radiological doses due to the assumed radioactive releases during the decommissioning phase were calculated in reference to the characterization of the studied area by collection of environmental parameters, such as climatological, hydrological, geomorphological ones. The implementation of transport and diffusion specific models of some radionuclides in the environment was another step for the dose calculation using specific evaluation software: VADOSCA (an Italian software used for Italian NPPs), PC-PREAM (by English NRPB), FRAMES (by American NPL). The second part of the study focuses on the project of an environmental network designed in order to ensure the continuous monitoring of the radioactive release concentrations. All the criteria for the choice of grid points, on the basis of specific paths of transfer in the environment, were established for all the environmental compartments. This study was supported by a field campaign, with the aim to assess the 'zero level' due to the natural radioactivity and past anthropogenic activities, and by laboratory measurements (gamma detection by HPGe for different natural and anthropogenic gamma-emitters), so that the measured radioactive concentrations can be compared to the calculated ones. This work is an example of applied radioecological study on contaminated sites focused on the project of a planned monitoring grid for all environmental compartments (i.e. atmospheric, marine, freshwater and terrestrial) that will be used during the decommissioning release activities, but it could also be the basis for

  2. Preliminary study on the relation between the coping patterns and mental health of radiation control personnel and nondestructive inspectors engaged in the periodic inspections of nuclear power plants.

    Science.gov (United States)

    Nagaoka, Chika; Uchida, Yukiko

    2014-01-01

    In order to safely manage nuclear power plants, their workforce should be mentally healthy. This study clarifies the coping strategies of radiation control personnel and nondestructive inspectors engaged in the periodic inspection of nuclear power plants, the effect of the coping strategies on their mental health, as well as any effect based on whether or not they had worked after the nuclear disaster caused by the Great East Japan Earthquake and tsunami in March 2011. A questionnaire survey was administered to 133 technicians attending a certification course, and among them, our subjects of analysis were 104 people with work experience in radiation control and/or nondestructive inspection. The results indicated that even among workers of the same company who were assigned to similar duties in the periodic inspections of nuclear power plants, the group that had worked at a nuclear plant after the disaster had a tendency to use coping strategies, such as giving up and avoidance-like thinking, which was dissimilar to the group that had not worked at a nuclear plant after the disaster. Further, the former group had higher levels of distress than those who tended to use other coping strategies. In addition, the results suggested that the plan-drafting strategy adopted by the group that had not worked after the disaster did not result in stress reduction. Based on these results, we propose a stress management program specifically for radiation workers.

  3. Alma Mater: 2014/ Pavasaris

    OpenAIRE

    Latvijas Universitāte. Preses centrs

    2014-01-01

    Andra Čudare. Studentu students Rūta Mājeniece -- Studiju prakse - piedzīvo grāmatās rakstīto -- Lauma Abramoviča. Inta Brūna: cilvēks var padarīt ļoti daudz, ja vēlas -- LU Preses centrs. Prezentē jaunās Zobārstniecības mācību klīnikas telpas un programmu -- LU Preses centrs. Latvijas Universitāte Eiropas kultūras kontekstā -- Katrīna Žukova. LU dienesta romāni un mīlas stāsti -- Grācija Tafuni. Nevīžība un precizitāte: vienas medaļas divas puses -- Santa Margēviča. Klase aizraujošām mācībām...

  4. Análisis de la construcción de la agencia social de las mujeres: estudio de caso: mesa de género de Puente Piedra.

    OpenAIRE

    Necochea Salguero, Meylí

    2013-01-01

    El problema sociológico que se estudia en este trabajo utiliza el concepto de agencia social para explicar el proceso de construcción de la capacidad de acción que va adquiriendo la Mesa de Género de Puente Piedra (MGPP), colectivo de mujeres formado en el 2006, que busca el reconocimiento del gobierno local del distrito para institucionalizar una agenda particular y convertirla en asunto público. Tesis

  5. Technical evaluation of the electrical, instrumentation, and control design aspects of the low temperature overpressure protection system for the Point Beach Nuclear Power Plant, Units 1 and 2

    Energy Technology Data Exchange (ETDEWEB)

    Laudenbach, D.H.

    1979-03-01

    The technical evaluation is presented for the electrical, instrumentation, and control design aspects of the low temperature overpressure protection system for the Point Beach nuclear power plant, Units 1 and 2. Design basis criteria used to evaluate the acceptability of the system included operator action, system testability, single failure criterion, and seismic Category I and IEEE Std-279-1971 criteria. This report is supplied as part of the Selected Electrical, Instrumentation, and Control Systems Issues Support Program being conducted for the U.S. Nuclear Regulatory Commission by Lawrence Livermore Laboratory.

  6. Survey on quality control of radiopharmaceutical dose calibrators in nuclear medicine units in the city of São Paulo, SP, Brazil

    OpenAIRE

    Bessa, Ana Carolina Moreira de; Costa, Alessandro Martins da; Caldas, Linda V. E.

    2008-01-01

    OBJETIVO: Realizar levantamento sobre quais testes de controle de qualidade são realizados nos calibradores de dose dos serviços de medicina nuclear da cidade de São Paulo, SP. Estudar a exatidão das medições de atividade de sete calibradores de dose no Laboratório de Calibração de Instrumentos do Instituto de Pesquisas Energéticas e Nucleares, usando fontes de radionuclídeos importantes clinicamente. MATERIAIS E MÉTODOS: O levantamento sobre o controle de qualidade foi realizado a partir de ...

  7. Efecto de un plan educativo en la capacidad de agencia de autocuidado del paciente con hipertensión arterial en una institución de segundo nivel

    Directory of Open Access Journals (Sweden)

    Diana Marcela Achury-Saldaña

    2013-01-01

    Full Text Available El propósito de este estudio fue determinar el efecto de un plan educativo en la capacidad de agencia de autocuidado del pa- ciente hipertenso en una institución de segundo nivel. Materiales y métodos: se realizó un estudio de intervención pre y postest, con la participación de 83 pacientes con diagnóstico de hipertensión arterial, a quienes se les aplicó el instrumento “ Evaluación de la capacidad de agencia de autocuidado en el paciente hipertenso ” al inicio del estudio y tres meses posteriores a la implementación del plan educativo. Resultados: el plan educativo mejoró tanto la capacidad de agencia de autocuidado global como sus rangos, encontrando significancia estadística con un valor de probabilidad menor de 0,002 y de 0,0001 respectivamente. Conclusiones: las intervenciones educativas estructuradas a partir de la identificación de las necesidades individuales de información, en conjunto con el empoderamiento del individuo y el seguimiento por parte del profesional de enfermería, permiten alcanzar conductas permanentes de autocuidado que facilitan el autoconocimiento, la modificación del comportamiento así como la adquisición de conocimientos y habilidades.

  8. Automation inflicted differences on operator performance in nuclear power plant control rooms

    Energy Technology Data Exchange (ETDEWEB)

    Andersson, Jonas; Osvalder, A.L. [Chalmers Univ. of Technology, Dept. of Product and Producton Development (Sweden)

    2007-03-15

    Today it is possible to automate almost any function in a human-machine system. Therefore it is important to find a balance between automation level and the prerequisites for the operator to maintain safe operation. Different human factors evaluation methods can be used to find differences between automatic and manual operations that have an effect on operator performance; e.g. Predictive Human Error Analysis (PHEA), NASA Task Load Index (NASA-TLX), Halden Questionnaire, and Human Error Assessment and Reduction Technique (HEART). Results from an empirical study concerning automation levels, made at Ringhals power plant, showed that factors as time pressure and criticality of the work situation influenced the operator's performance and mental workload more than differences in level of automation. The results indicate that the operator's attention strategies differ between the manual and automatic sequences. Independently of level of automation, it is essential that the operator retains control and situational understanding. When performing a manual task, the operator is 'closer' to the process and in control with sufficient situational understanding. When the level of automation increases, the demands on information presentation increase to ensure safe plant operation. The need for control can be met by introducing 'control gates' where the operator has to accept that the automatic procedures are continuing as expected. Situational understanding can be established by clear information about process status and by continuous feedback. A conclusion of the study was that a collaborative control room environment is important. Rather than allocating functions to either the operator or the system, a complementary strategy should be used. Key parameters to consider when planning the work in the control room are time constraints and task criticality and how they affect the performance of the joint cognitive system.However, the examined working

  9. Joint System Prognostics For Increased Efficiency And Risk Mitigation In Advanced Nuclear Reactor Instrumentation and Control

    Energy Technology Data Exchange (ETDEWEB)

    Donald D. Dudenhoeffer; Tuan Q. Tran; Ronald L. Boring; Bruce P. Hallbert

    2006-08-01

    The science of prognostics is analogous to a doctor who, based on a set of symptoms and patient tests, assesses a probable cause, the risk to the patient, and a course of action for recovery. While traditional prognostics research has focused on the aspect of hydraulic and mechanical systems and associated failures, this project will take a joint view in focusing not only on the digital I&C aspect of reliability and risk, but also on the risks associated with the human element. Model development will not only include an approximation of the control system physical degradation but also on human performance degradation. Thus the goal of the prognostic system is to evaluate control room operation; to identify and potentially take action when performance degradation reduces plant efficiency, reliability or safety.

  10. Control of the axial offset in a nuclear reactor at power maneuvering

    Directory of Open Access Journals (Sweden)

    Maksim V. Maksimov

    2014-12-01

    Full Text Available High reliability and security of power unit are basic requirements when the power unit maneuvering mode operation. The reactor stability under disturbances both at steady load and maneuvering load embodies the guarantees of power unit safe and reliable operation. A quantitative measure of the reactor stability is assessed by the axial offset representing the technological characteristics of energy release uniformity, therefore the axial offset minimum deviation is WWER-1000 operation efficiency measure. The power unit capacity automated control systems’ influence on axial offset under maneuvering mode is investigated. Considered is the power unit compromise-combined control program, which maintains a constant axial offset value when power unit switching from one power level to another.

  11. A Agência Brasileiro-Argentina de Contabilidade e Controle de Materiais Nucleares: uma Leitura Neoliberal Institucionalista

    Directory of Open Access Journals (Sweden)

    Diego Felipe Antunes

    2016-12-01

    Full Text Available A América Latina é uma região rica em arranjos institucionais responsáveis por avançar processos de integração regional. Dentro dessa vastidão, alguns casos específicos acabam perdendo-se, independentemente de seu sucesso ou fracasso. Buscando contribuir para a bibliografia que procura suprir essa deficiência, o presente trabalho tem como objetivo analisar o processo de formação e a atuação de um caso bem-sucedido de integração: a Agência Brasileiro-Argentina de Contabilidade e Controle de Materiais Nucleares (ABACC. Tal análise busca responder a seguinte pergunta: quais elementos explicam esse sucesso? A hipótese é a de que proposições neoliberal-institucionalistas são aptas a oferecer tal explicação. Para tal, faz-se uso da teoria Neoliberal Institucionalista para compreender de que forma essa agência contribuiu para o fim das tensões nucleares entre Brasil e Argentina no fim do século passado. O artigo se divide em três seções: na primeira, realiza-se uma discussão acerca do Neoliberalismo Institucionalista, suas propostas, críticas e choques com o Neorrealismo; em seguida, o processo histórico de formação da ABACC, bem como seus meios de atuação, é apresentado; por fim, a terceira seção realiza um esforço de leitura da atuação da agência a partir do instrumental teórico neoliberal.

  12. [Guidelines for radiation protection in medicine--radiopharmaceutical quality control. German Society of Nuclear Medicine].

    Science.gov (United States)

    Brandau, W

    1994-04-01

    For the first time the revision of the "Guideline for radiation protection in medicine" defines extensive quality control procedures for radiopharmaceuticals. The principles of the 99Mo/99mTc-generator, the preparation of 99mTc-radiopharmaceuticals and the origin of the most frequent radiochemical impurities are illustrated. An introduction into the theory of thin layer chromatography is combined with a listing of radiochromatographic systems. This enables the determination of the radiochemical purity of the most important radiopharmaceuticals in clinical routine.

  13. Nuclear Parity with China?

    Science.gov (United States)

    2012-01-01

    Comprehensive Nuclear-Test- Ban Treaty (CTBT) in 1996, and applied for membership in the Missile Technology Control Regime (MTCR) in 2004. Since at least the...first nuclear test ban agreements? Is the United States seeking to gain relative advantage under the guise of nuclear parity? Caroline Ziemke-Dickens...of what senior State Department officials call “doing our homework ” for future arms control negotiations, and even there is has a low standing

  14. Diseño de un modelo de scoring para la gestión eficiente de la cartera en una agencia de cobranzas

    Directory of Open Access Journals (Sweden)

    Luis David Delgado Vélez

    2017-06-01

    Full Text Available El objetivo de esta investigación es diseñar un modelo de scoring para el manejo eficiente de la cartera en una agencia de cobranzas en Colombia. Para ello, se utilizó un modelo de regresión logística con una base de datos de 16.000 clientes morosos de bancos, cooperativas y empresas de servicios públicos. Los resultados indican que, según las características socioeconómicas, la morosidad, los ingresos y el endeudamiento, el 50% de las carteras comercial, de consumo y microcrédito son recuperables. En conclusión, los modelos de scoring son de gran utilidad para la gestión financiera, dado que facilita la implementación de políticas de ventas en términos de plazos y cupos, además de realizar seguimientos más individualizados a sus clientes.

  15. Niñas y niños colombianos en los Estados Unidos. Agencia, identidades y cambios culturales alrededor de la comida

    Directory of Open Access Journals (Sweden)

    María Claudia Duque Páramo

    2008-01-01

    Full Text Available Con base en un estudio participativo y etnográfico realizado durante 2003 y 2004 en Tampa (Florida con niñas y niños colombianos entre siete y los doce años se explora la relación entre migración, niñez, agencia, alimentación y cultura. La idea central es que los niños migrantes son agentes y actores que construyen identidades que se expresan en sus prácticas y gustos alimentarios. A la manera de un fenómeno de creolización, los inmigrantes mezclan elementos culturales de la región de origen en Colombia con elementos del nuevo contexto en los Estados Unidos, produciendo nuevos y diferentes significados y símbolos culturales. Se resalta la importancia de hacer estudios de corte antropológico que permitan reconocer las sutilezas de las experiencias de los inmigrantes, así como reconocer y valorar a los niños como agentes que construyen culturas e identidades.

  16. Inferring Invasion History of Red Swamp Crayfish (Procambarus clarkii in China from Mitochondrial Control Region and Nuclear Intron Sequences

    Directory of Open Access Journals (Sweden)

    Yanhe Li

    2015-06-01

    Full Text Available Identifying the dispersal pathways of an invasive species is useful for adopting the appropriate strategies to prevent and control its spread. However, these processes are exceedingly complex. So, it is necessary to apply new technology and collect representative samples for analysis. This study used Approximate Bayesian Computation (ABC in combination with traditional genetic tools to examine extensive sample data and historical records to infer the invasion history of the red swamp crayfish, Procambarus clarkii, in China. The sequences of the mitochondrial control region and the proPOx intron in the nuclear genome of samples from 37 sites (35 in China and one each in Japan and the USA were analyzed. The results of combined scenarios testing and historical records revealed a much more complex invasion history in China than previously believed. P. clarkii was most likely originally introduced into China from Japan from an unsampled source, and the species then expanded its range primarily into the middle and lower reaches and, to a lesser extent, into the upper reaches of the Changjiang River in China. No transfer was observed from the upper reaches to the middle and lower reaches of the Changjiang River. Human-mediated jump dispersal was an important dispersal pathway for P. clarkii. The results provide a better understanding of the evolutionary scenarios involved in the rapid invasion of P. clarkii in China.

  17. Chloroplast biogenesis-associated nuclear genes: Control by plastid signals evolved prior to their regulation as part of photomorphogenesis.

    Directory of Open Access Journals (Sweden)

    Alison C HIlls

    2015-12-01

    Full Text Available The assembly of photosynthetically-competent chloroplasts occurs in angiosperm seedlings when first exposed to light, and is due to the control by light of photosynthesis-associated nuclear genes (PhANGs, also dependent upon plastid-to-nucleus biogenic communication signals. The relationship between light- and plastid signal-regulation of PhANGs is close but poorly understood. In contrast, many conifers green in the dark and the promoter of a pine PhANG, Lhcb, is active in the dark in tobacco. Here we show that the activity of this promoter in tobacco is sensitive to plastid photobleaching, or to the inhibition of plastid translation in the light or the dark, and the same interventions reduce expression of the native gene in pine seedlings, demonstrating classic plastid biogenic signalling in gymnosperms. Furthermore, Arabidopsis mutations causing defective plastid biogenesis suppress the effect in darkness of mutations in COP1 and DET1, repressors of photomorphogenesis, for the expression of several PhANGs but not a photosynthesis-unrelated, light-regulated gene. GLK transcriptional regulators mediate the response of LHCB but not of other tested PhANGs. We propose gain of the ability by repressors of photomorphogenesis to suppress the response of PhANG promoters to positive plastid biogenic signals in the dark to have contributed to the evolution of light control of chloroplast biogenesis.

  18. Asociación entre la capacidad de la agencia de autocuidado y la adherencia a tratamientos farmacológicos y no farmacológicos en personas con alguna condición de enfermedad coronaria

    Directory of Open Access Journals (Sweden)

    CLARA VICTORIA BASTIDAS SÁNCHEZ

    2007-12-01

    Full Text Available El propósito del estudio con un diseño descriptivo, transversal y correlacional- fue explorar la relación entre agencia de autocuidado y adherencia en 115 pacientes con enfermedad coronaria seleccionados intencionalmente de una población de pacientes coronarios que asistieron a la consulta de cardiología en una clínica de la ciudad de Ibagué durante cuatro meses del año 2005. Se midió la capacidad de la agencia con el instrumento Evaluación de la Capacidad de la Agencia de Autocuidado, validado en su versión al español, y se calculó la adherencia a tratamientos farmacológicos y no farmacológicos en el mismo grupo mediante una escala que corresponde al resultado de adherencia y sus indicadores de la taxonomía NOC acompañada de una guía de valoración. Esa escala traducida al español fue evaluada en su comprensión por un grupo de enfermeras con experiencia clínica y docente en el área. El perfil clínico del grupo consistió en tres grupos, de acuerdo con la complejidad del régimen de medicamentos: 24, 58, 911 y de la condición de la enfermedad coronaria con tratamiento convencional, enfermedad coronaria con tratamiento intervencionista y pacientes con falla coronaria. Mediante pruebas de correlación tipo Pearson se pudo confirmar una asociación moderadamente positiva entre la capacidad de la agencia de autocuidado y la adherencia a tratamientos farmacológicos y no farmacológicos, aspecto este que se había sugerido al proponer el estudio; es decir que la adherencia y la capacidad de la agencia de autocuidado son comportamientos positivos que están presentes con características similares en personas con enfermedad coronaria como las de esta muestra. Se confirmó que la complejidad del régimen terapéutico tiene influencia en la adherencia, aun cuando en este grupo solo se mostró en una manera leve pero positiva, concordante con lo encontrado en otros estudios reportados por la OMS.

  19. Fabrication of cermet bearings for the control system of a high temperature lithium cooled nuclear reactor

    Science.gov (United States)

    Yacobucci, H. G.; Heestand, R. L.; Kizer, D. E.

    1973-01-01

    The techniques used to fabricate cermet bearings for the fueled control drums of a liquid metal cooled reference-design reactor concept are presented. The bearings were designed for operation in lithium for as long as 5 years at temperatures to 1205 C. Two sets of bearings were fabricated from a hafnium carbide - 8-wt. % molybdenum - 2-wt. % niobium carbide cermet, and two sets were fabricated from a hafnium nitride - 10-wt. % tungsten cermet. Procedures were developed for synthesizing the material in high purity inert-atmosphere glove boxes to minimize oxygen content in order to enhance corrosion resistance. Techniques were developed for pressing cylindrical billets to conserve materials and to reduce machining requirements. Finishing was accomplished by a combination of diamond grinding, electrodischarge machining, and diamond lapping. Samples were characterized in respect to composition, impurity level, lattice parameter, microstructure and density.

  20. Quality control at the Regional Centre of Nuclear Sciences chemical dosimetry laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Souza, Vivianne L.B. de; Melo, Roberto T. de; Silva, Danubia B. da; Pedroza, Eryka H.; Rodrigues, Kelia R.G.; Cunha, Manuela S. da; Figueiredo, Marcela D.C. de [Centro Regional de Ciencias Nucleares (CRCN-NE/CNEN-PE), Recife, PE (Brazil); Oliveira, Aristides, E-mail: vlsouza@cnen.gov.b, E-mail: rtmelo@cnen.gov.b [Hospital de Cancer de Pernambuco, Recife, PE (Brazil)

    2011-07-01

    Standards for accreditation of laboratories as in ISO 9001 in section: 4.11 require inspection, measuring and equipment testing; likewise, IEC 17025: 2005 in section: 5.5.2 requires the equipment to be calibrated or verified before being put into use. In our laboratory, quality control is often accomplished by standards set done by the laboratory scientists themselves; however, at present, Hellma secondary calibration standards (4026 - Holmium oxide - Filters: F0, F2, F3, F4 and filter didymium - F7) have been used in order to verify if errors in the laboratory have been close to the 1-2% margin. Control graphs were made by using the results of synthetically prepared standards and standardized spectral calibration certificates. The set of secondary calibration standards permits to check the accuracy of the spectrophotometers used in research for both the absorbance in the visible spectrum (at 440, 465, 546, 590 and 635 nm wavelengths) and for the wavelengths (270, 280, 300, 320 nm) of the ultraviolet light. Filters (F0, F2, F3, F4 and F7) are stable and do not suffer the influence of temperature (the influence is negligible), the F0 filter was being used as a blank. The purpose is to verify whether the spectrometer needs adjustments, an important procedure to check absorbance stability, baseline flatness, slit width accuracy and stray radiation. The calibration tests are performed annually in our laboratory and recalibration of Hellma secondary standards is recommended every two years. The results show that the Chemical Dosimetry Laboratory in CRCN has a calibrated spectrophotometer and their synthetic standards for Fricke dosimetry could be used as an alternative method for testing the proficiency and competence of calibration laboratories in accordance with the regulations and standards. (author)