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Sample records for brasil-argentina agencia contabil controle mater nuclear

  1. A integração bilateral Brasil-Argentina: tecnologia nuclear e Mercosul

    Directory of Open Access Journals (Sweden)

    Odete Maria de Oliveira

    1998-06-01

    Full Text Available O presente trabalho focaliza o complexo processo de integração bilateral Brasil-Argentina, iniciado formalmente na década de 80, desdobrado em sua dupla abrangência: a cooperação pacífica da tecnologia nuclear; b constituição de um mercado comum. A evolução desse processo conduziu-se através de ciclos fundamentais: primeira etapa, antecedentes de aproximação; segunda etapa, os decisivos instrumentos da ampla integração; terceira etapa, solidificação de duas bases, uma de nível tecnológico nuclear, pactuando um sistema sui generis de salvaguardas e a vigência do Tratado de Tlatelolco (emendado, e, outra, de nível econômico pelo Tratado de Assunção, instituindo o Mercosul.The present work focuses on the complex bilateral integration process involving Brazil and Argentina that began formally during the 80's, and displayed in its double scope: a pacific cooperation on nuclear technology; b constitution of a common market. This process evolution took place in three fundamental circles: the first one, approximation antecedents; the second one, decisive instruments for a large integration; and the third one, the solidification of two basis, one at the nuclear technological level, joining the two countries in the sui generis back up system and the operation of the Tlatelolco Treaty, the other, at the economic level instituting the Mercosur by the Asunción Treaty.

  2. ABACC - Brazil-Argentina Agency for Accounting and Control of Nuclear Materials, a model of integration and transparence; ABACC - Agencia Brasileno-Argentina de Contabilidad y Control de Materiales Nucleares, un ejemplo de integracion y transparencia

    Energy Technology Data Exchange (ETDEWEB)

    Oliveira, Antonio A.; Do Canto, Odilon Marcusso, E-mail: oliveira@abacc.org.br, E-mail: odilon@abacc.org.br [Agencia Brasileno Argentina de Contabilidad y Control de Materiales Nucleares (ABACC), Rio de Janeiro, RJ (Brazil)

    2013-07-01

    Argentina and Brazil began its activities in the nuclear area about the same time, in the 50 century past. The existence of an international nuclear nonproliferation treaty-TNP-seen by Brazil and Argentina as discriminatory and prejudicial to the interests of the countries without nuclear weapons, led to the need for a common system of control of nuclear material between the two countries to somehow provide assurances to the international community of the exclusively peaceful purpose of its nuclear programs. The creation of a common system, assured the establishment of uniform procedures to implement safeguards in Argentina and Brazil, so the same requirements and safeguards procedures took effect in both countries, and the operators of nuclear facilities began to follow the same rules of control of nuclear materials and subjected to the same type of verification and control. On July 18, 1991, the Bilateral Agreement for the Exclusively Peaceful Use of Nuclear Energy created a binational body, the Argentina-Brazil Agency for Accounting and Control of Nuclear Materials-ABACC-to implement the so-called Common System of Accounting and Control of Nuclear materials - SCCC. The deal provided, permanently, a clear commitment to use exclusively for peaceful purposes all material and nuclear facilities under the jurisdiction or control of the two countries. The Quadripartite Agreement, signed in December of that year, between the two countries, ABACC and IAEA completed the legal framework for the implementation of comprehensive safeguards system. The 'model ABACC' now represents a paradigmatic framework in the long process of economic, political, technological and cultural integration of the two countries. Argentina and Brazil were able to establish a guarantee system that is unique in the world today and that consolidated and matured over more than twenty years, has earned the respect of the international community.

  3. ABACC: annual report 2012 - Brazilian-Argentine Agency for the Accounting and Control of Nuclear Materials; ABACC: informe annual 2012 - Agencia Brasileiro-Argentina de Contabilidade e Controle de Materiais Nucleares

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2012-07-01

    This document reports the actives during the year 2012 related to: technical activities as safeguards application and advances in application of safeguards; main activities conducted in Brazil and main activities developed at ABACC headquarters; management of the Quadripartite Agreement and of the SCCC - Common System for Accounting and Control of Nuclear Materials; training; technical cooperation; institutional, administrative and financial activities; perspectives for 2013; list of inspectors; list of Brazilian and Argentine facilities subject to the Quadripartite Agreement.

  4. Nuclear control

    Energy Technology Data Exchange (ETDEWEB)

    Yoon, Wan Kee [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)

    1995-02-01

    International cooperation in nuclear industries requires nuclear control as prerequisites. The concept of nuclear control is based on the Treaty on the Non-proliferation of Nuclear Weapon (NPT). The International Atomic Energy Agency (IAEA) plays central role in implementing nuclear control. Nuclear control consists of nuclear safeguards, physical protection, and export/import control. Each member state of NPT is subject to the IAEA`s safeguards by concluding safeguards agreements with the IAEA. IAEA recommends member states to implement physical protection on nuclear materials by `The Physical Protection of Nuclear Material` and `The Convention on the Physical Protection of Nuclear Material` of IAEA. Export/Import Control is to deter development of nuclear weapons by controlling international trade on nuclear materials, nuclear equipments and technology. Current status of domestic and foreign nuclear control implementation including recent induction of national inspection system in Korea is described and functions of recently set-up Technology Center for Nuclear Control (TCNC) under the Korea Atomic Energy Research Institute (KAERI) are also explained. 6 tabs., 11 refs. (Author).

  5. A rivalidade Brasil-Argentina e a Guerra Fria

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    Carlos Eduardo Vidigal

    2014-12-01

    Full Text Available Peronismo e anti-peronismo definiram o padrão da rivalidade Brasil-Argentina no contexto do início da guerra fria. Inúmeros documentos diplomáticos brasileiros – ofícios, despachos, memorandos, telegramas – datados dos anos de 1946 a 1948 apresentavam em seus títulos temas como “infiltração argentina no Sul do Brasil”, “expansionismo político da Argentina”, “política expansionista da Argentina”, etc. Pode-se afirmar que o anti-peronismo consolidou-se em setores dirigentes do país, por meio de uma política que ultrapassava, de algum modo, o próprio peronismo. Por exemplo, a ideia de que a Argentina procurava expandir sua área de influência na América do Sul remonta, pelo menos ao período anterior a segunda grande guerra. Assim, a identificação da forma como se construiu o anti-peronismo no Brasil permite avaliar mais especificamente que interesses e quais setores alimentaram visões contrárias ao diálogo bilateral.

  6. The Nuclear and Safety Council and the Nuclear Energy Agency; El Consejo de Seguridad Nuclear y la Agencia de Energia Nuclear. Una estrecha colaboracion

    Energy Technology Data Exchange (ETDEWEB)

    Martinez Ten, C.

    2008-07-01

    On the occasion of the fiftieth anniversary of creation of the Nuclear Energy Agency (NEA), specialised agency within the Organisation for Economic Cooperation and Development (OECD), the President of the Spanish Nuclear Safety Council (CSN), summarizes the activities of the NEA throughout its life up to now. Since it started up, the CSN has worked closely with this international organization, as a reflection of the strong commitment, shared by both institutions, each one in its field, to reach the highest levels in the regulation which contributes decisively to the nuclear safety of the Spanish nuclear power plants. (Author)

  7. The accountability of the brazilian regulatory agencies: the experience of the National Petroleum Agency; O controle externo das agencias reguladoras: o caso da Agencia Nacional do Petroleo

    Energy Technology Data Exchange (ETDEWEB)

    Pinto Junior, Helder Queiroz; Borges, Heloisa Lopes [Universidade Federal do Rio de Janeiro (UFRJ), RJ (Brazil). Inst. de Economia. Grupo de Economia da Energia

    2004-07-01

    During the reform process for which passed the Brazilian Oil and Gas Industry, the academic debate was centered mostly in the sectorial restructuring process, in the contract designs and regulatory environment for the industries in change, particularly the desired attributes of its institutions. The debate tends, in the present, to converge towards the existence of different possible combinations between market structures and institutional structures (the regulators among them) that would lead to a desirable result. Thus, the various characteristics and configurations, originally appointed as necessary conditions for the success of any reform, are not dealt with such great deference anymore. The hypothesis that the existence of a independent regulator is a determinant choice for the success of structural and institutional reforms was relaxed as general rule, but there are still strong economic reasons to justify the option, adopted in Brazil. The creation of the Oil National Agency (ANP), the Brazilian regulator for the Oil and Gas Industry is a recent phenomenon. And few studies specifically approach the issue of its accountability, institutional role that in Brazil is delegated mostly, but not exclusively, to the National Court of Accounts (Tribunal de Contas da Uniao). Therefore, the objective of this work will be to discuss the different possibilities of accountability over the ANP, evaluating the paper and the functions of the TCU and the forms of external control on the Agency, pointing out the possibilities, the impediments and the challenges, as well as the economic consequences to the Natural Gas Industry of the current configuration. (author)

  8. The "RESEAU MATER": An efficient infection control for endometritis, but not for urinary tract infection after vaginal delivery.

    Science.gov (United States)

    Ayzac, Louis; Caillat-Vallet, Emmanuelle; Girard, Raphaële; Berland, Michel

    2016-09-01

    "RESEAU MATER" is useful to monitor nosocomial infections in maternity and contributes to the decreasing trend of it, since its implementation. Specifically, this network demonstrates its efficiency in the control of endometritis following vaginal deliveries, but not in the control of urinary tract infections. The aim of this study is to determine whether the difference between the control of endometritis and of urinary tract infection could be explained by an unsuitable regression model or by an unsuitable care policy concerning urinary cares. This study includes (1) the analysis of historic data of the network and (2) the description of French guidelines for maternity cares and available evaluations, concerning endometritis and urinary tract infection prevention. Univariate and multivariate odds ratios (ORs) were calculated for the total study period of 1999-2013, for these infections and their risk factors. The endometritis frequency is decreasing, in association with no significant evolution of associated risk factors, but urinary tract infection frequency is constant, in association with a increasing trend of its risk factors such as intermittent catheterization and epidural analgesia. In French guidelines, all preventive measures against endometritis are clearly broadcasted by all field operators, and repeated audits have reinforced the control of their application. But preventive measures against urinary tract infection seem to be broadcasted exclusively in the circle of infection prevention agencies and not in the obstetrics societies or in the Health Ministry communication. Urinary tract infection prevention requires a clearer public and professional policy in favor of a more efficient urinary cares, with a specific target to maternity.

  9. Nanoscale Electrodes: Nanoscale Electrodes for Flexible Electronics by Swelling Controlled Cracking (Adv. Mater. 30/2016).

    Science.gov (United States)

    Zhao, Qiang; Wang, Wenjun; Shao, Jinyou; Li, Xiangming; Tian, Hongmiao; Liu, Lu; Mei, Xuesong; Ding, Yucheng; Lu, Bingheng

    2016-08-01

    The fabrication of nanospaced electrodes on a flexible substrate is a great challenge. W. Wang, J. Shao, and co-workers propose a novel approach to fabricate nanogap electrodes for flexible electronics using a swelling-controlled cracking method, which is described on page 6337. This method has the advantages of high applicability, parallel manufacturing capacity, and compatibility with flexible substrates. It provides a new way to create high-performance flexible electronics in a cost-efficient fashion.

  10. #LADM: la agencia de medios

    OpenAIRE

    Castelló Martínez, Araceli (1981-)

    2013-01-01

    El libro pretende ser un manual dedicado a la agencia de medios, actor protagonista hoy en día en la industria publicitaria, desde un enfoque práctico y afín a la realidad profesional. En “#LADM: la agencia de medios” se repasa la evolución histórica de la agencia de medios, su estructura y funciones en el proceso publicitario, el proceso de trabajo en investigación de medios y planificación publicitaria a partir de la revisión de los principales documentos de trabajo, las relaciones de la ag...

  11. Mujeres, esfera pública y populismo en Brasil, Argentina y Ecuador, 1870-1960

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    Ximena Sosa-Buchholz

    2008-06-01

    Full Text Available Este trabajo se enfoca en las luchas de las mujeres para convertirse en actores políticos en tres países latinoamericanos: Brasil, Argentina y Ecuador. Analiza la educación de las mujer es como un factor decisivo para obtener el derecho al voto e ingresar a la arena pública mediante la publicación de periódicos. Se estudia la manera como las mujeres crearon sus propias organizaciones políticas, muchas de las cuales fueron respaldadas por liberales, conservadores e incluso socialistas. A pesar de que la lucha para conquistar el voto femenino fue una combinación entre las organizaciones de derechos femeninos, el diálogo interamericano y el apoyo de figuras públicas masculinas, fueron los líderes populistas quienes aprobaron el derecho al voto femenino. Ellos usaron este derecho para atraer el voto femenino en sus reelecciones presidenciales.

  12. Stabat Mater. Chant gregorien / Patric Wiklacz

    Index Scriptorium Estoniae

    Wiklacz, Patric

    1997-01-01

    Uuest heliplaadist "Stabat Mater. Chant gregorien. Palestrina: Stabat Mater a 8; Pärt: Stabat Mater; Browne: Stabat Mater dolorosa a 6. Fretwork (concort de violes)". Virgin Classics 545 272-2 (CD: 167F)

  13. Invasive vertebrate species in Chile and their control and monitoring by governmental agencies Especies de vertebrados invasores en Chile y su control y monitoreo por agencias gubernamentales

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    J. AGUSTÍN IRIARTE

    2005-03-01

    Full Text Available We provide an overview of the current status of vertebrate invasive species throughout Chile, updating information on terrestrial exotics and reporting for the first time the situation of exotic freshwater fishes. In addition, we document the legislation and programs that the Chilean government has implemented to limit the entry of exotics to the country or minimize their impact on native wild flora and fauna and on natural ecosystems. We document what is known about the introduction of 26 exotic fish species to continental waters of the country, discussing the distribution and putative effects of those 11 species that may be considered invasive. From a previous list of 24 terrestrial vertebrate invaders, we withdraw the Argentine tortoise (Chelonoidis chilensis, reindeer (Rangifer tarandus and mouflon (Ovis ammon because there are no data on their subsistence in the wild. On the other hand, we add three new species: red-eared freshwater turtle (Trachemys scripta, monk parakeet (Myiopsitta monachus, and red-crested cardinal (Paroaria coronata, thus keeping the total number of terrestrial invaders unchanged at 24 species. The chief agency in charge of existing laws and regulations regarding the import of exotic freshwater species is the National Fisheries Service (SERNAPESCA, in Spanish, a dependency of the Ministry of Economy. The main agency in charge of enforcing existing laws and regulations regarding the import of exotic terrestrial species to Chile is the Agriculture and Livestock Service (SAG, in Spanish, a dependency of the Ministry of Agriculture. Currently, SAG is not only controlling major border passes, seaports and airports, but also is funding studies to monitor and control already existing invaders. In addition, the Chilean Forest Service (CONAF, in Spanish is also concerned about invasive species, but only if they enter national parks and reserves within the National System of Protected Wildlife Areas (SNASPE, in Spanish

  14. From Virgil to Alma Mater

    Science.gov (United States)

    Spitz, Ellen Handler

    2007-01-01

    For a college to become an alma mater in the hearts of its students, it must show, true to the Latin meaning, the wisdom and comfort of a good foster mother. Since "alma mater" is Latin, and since the study of Latin has waned on all educational levels in both pious and secular milieus, the author wonders whether folks who use that term really know…

  15. El contrato de agencia comercial

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    María Elisa Camacho López

    2008-12-01

    Full Text Available Uno de los compromisos asumidos por el Gobierno de la República de Colombia en el Tratado de Libre Comercio celebrado con el Gobierno de los Estados Unidos, cuyo texto aún no ha entrado en vigor, consiste en la eliminación o modificación de algunos de los elementos que regulan el contrato de Agencia Comercial, los cuales, a su vez, valga la pena resaltar, nunca han gozado de una pacífica comprensión. Razón por la cual, aprovechando ambas circunstancias, hemos querido analizar el proceso de tipificación de este contrato a nivel global, desde sus inicios hasta sus más recientes desarrollos, con el objeto de determinar la conveniencia de los cambios solicitados.

  16. Própolis produzida no sul do Brasil, Argentina e Uruguai: evidências fitoquímicas de sua origem vegetal

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    Park Yong Kun

    2002-01-01

    Full Text Available A própolis é uma substância resinosa coletada pelas abelhas de diversas partes da planta. Sua composição depende da época, vegetação e área de coleta. Própolis produzida por abelhas Apis mellifera africanizada do sul do Brasil, Argentina e Uruguai foram investigadas por meio de técnicas cromatográficas. De acordo com os resultados obtidos por CCDAE-FR, CLAE-FR e CG-EM, as própolis do sul do Brasil foram classificadas em 5 grupos distintos. Com base nas evidências fitoquímicas, Populus alba foi identificada como a principal fonte da própolis do grupo 3 do sul do Brasil, Argentina e Uruguai.

  17. Problema de la agencia y la cultura corporativa estalinista

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    Yurí Gorbaneff

    2004-12-01

    Full Text Available El problema de la agencia es de los obstáculos para la eficiencia de las organizaciones. A partir de Alchian y Demsetz (1972.la teoría sugiere dos soluciones: la propiedad privada y la cultura corporativa. Sin embargo, aislar el efecto de la cultura sobre las organizaciones no es fácil. La "ingeniería social" estalinista ofrece un material interesante para evaluar los efectos de la cultura corporativa sobre el sistema económico. Acá se sostiene la hipótesis de que los dirigentes soviéticos, al enfrentar los crecientes costos de la agencia tuvieron que inventar otra método, que no fuera la propiedad privada ni el control democrático directo sobre el aparato productivo, para controlar la pérdida de la agencia. Ellos recurrieron a la implantación de la cultura corporativa heroica a nivel nacional. Este trabajo muestra que la propaganda política, el arte, la literatura, los movimientos populares y el culto a la personalidad de Stalin fueran las herramientas gerenciales clave para implantar la cultura corporativa heroica, indispensable en la economía planificada. Su aplicación fue exitosa y generó las condiciones necesarias para la industrialización entre 1920 y 1930 y para el alto desempeño de la economía soviética durante la Segunda Guerra Mundial. La segunda hipótesis consiste en que el fantasma de la agencia, ahuyentado entre 1920 y 1950 por la cultura heroica estalinista, terminó devorando la economía planificada.

  18. Global nuclear material control model

    Energy Technology Data Exchange (ETDEWEB)

    Dreicer, J.S.; Rutherford, D.A.

    1996-05-01

    The nuclear danger can be reduced by a system for global management, protection, control, and accounting as part of a disposition program for special nuclear materials. The development of an international fissile material management and control regime requires conceptual research supported by an analytical and modeling tool that treats the nuclear fuel cycle as a complete system. Such a tool must represent the fundamental data, information, and capabilities of the fuel cycle including an assessment of the global distribution of military and civilian fissile material inventories, a representation of the proliferation pertinent physical processes, and a framework supportive of national or international perspective. They have developed a prototype global nuclear material management and control systems analysis capability, the Global Nuclear Material Control (GNMC) model. The GNMC model establishes the framework for evaluating the global production, disposition, and safeguards and security requirements for fissile nuclear material.

  19. Technical supports for nuclear control

    Energy Technology Data Exchange (ETDEWEB)

    An, Jong Sung; Kwak, Eun Hoh; Noh, Sung Kee; Soh, Dong Sub; Yoon, Wan Kee; Shin, Jang Soo; Paek, Dae Hyun; Park, Wan Soo; Kim, Hyun Tae; Park, Chan Sik; Cha, Hong Yul; Choi, Yoon Dong; Park, Jin Hoh; Lee, Eui Jin; An, Jin Soo; Kim, Jong Heui [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)

    1994-12-01

    The project was carried out to support the establishment of the system of accountancy and control of nuclear materials in Korea. The training of inspectors and seminar were held to improve inspection capability of the nuclear inspectors. The information about the north Korean nuclear activities were successfully analyzed. In the drafts of nuclear energy law the national inspection and the regulation of physical protection were newly introduced for the purpose to clarify the openness of nuclear activities in Korea. 1 fig, 20 tabs, 19 refs. (Author).

  20. Controlled Nuclear Fusion.

    Science.gov (United States)

    Glasstone, Samuel

    This publication is one of a series of information booklets for the general public published by The United States Atomic Energy Commission. Among the topics discussed are: Importance of Fusion Energy; Conditions for Nuclear Fusion; Thermonuclear Reactions in Plasmas; Plasma Confinement by Magnetic Fields; Experiments With Plasmas; High-Temperature…

  1. Treatment for infection of artificial dura mater using free fascia lata.

    Science.gov (United States)

    Nakano, Takashi; Yoshikawa, Katsuhiro; Kunieda, Takeharu; Arakawa, Yoshiki; Kikuchi, Takayuki; Yamawaki, Satoko; Naitoh, Motoko; Kawai, Katsuya; Suzuki, Shigehiko

    2014-07-01

    Synthetic artificial dura mater materials, such as expanded polytetrafluoroethylene sheets, are widely used in dura mater reconstruction in cases involving brain tumors or trauma surgery. In patients with postoperative infection related to the use of artificial dura mater, surgical debridement of the infected wound and removal of the artificial dura mater materials are necessary to control infection. In cases involving cerebrospinal fluid leakage, dura mater reconstruction must be performed immediately. Many useful techniques for performing dura mater reconstruction to treat postoperative infection have been reported; however, some have drawbacks with respect to the need for microvascular anastomosis or difficulties in obtaining watertight closure. We successfully treated 6 patients with postoperative artificial dura mater infection using free thigh fascia lata. Some surgeons believe that the use of free fascia in infected wounds is dangerous because free fascia is a non-vascularized tissue. However, performing complete debridement and covering such free fascia with well-vascularized tissue allow the fascia to become vascularized and tolerant of infection. Therefore, if the blood flow in the scalp is acceptable after a sufficient debridement, free fascia lata can be used for reconstruction in patients with postoperative infection of artificial dura mater. Furthermore, skull reconstruction can be performed safely and easily with solid-type artificial bone, sometimes combined with tissue expansion, thus resulting in good aesthetic outcomes.

  2. A informação contabilística nas decisões financeiras das pequenas empresas

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    Leonor da C. Ferreira Nunes

    2004-12-01

    Full Text Available O presente artigo tem por objectivo analisar a importância da informação contabilística atribuída pelos empresários/gestores das pequenas empresas na tomada de decisão estratégica (que comporta as decisões de investimento, financiamento e distribuição de dividendos e operacional (relacionada com as decisões de gestão corrente. Assim como, verificar se existem grupos distintos de empresas na importância atribuída à informação contabilística segundo as decisões estratégicas e operacionais e se esses grupos se distinguem entre si, quando a contabilidade é feita na própria empresa ou por um gabinete de contabilidade/consultadoria externa. Os resultados evidenciam que os empresários/ gestores atribuem uma maior importância à informação contabilística nas decisões de investimento e operacionais do que nas decisões de financiamento e distribuição de dividendos. Constatou-se que, quando a contabilidade é feita na própria empresa, os empresários/gestores atribuem maior importância à informação contabilística tanto nas decisões estratégicas como operacionais.This paper analyzes the role of accounting information for small firms' owners and/or managers for financial (i.e. for making decisions on investment, financing and dividends as well as operational decision making. Furthermore, this research aims to identify different groups of firms regarding the importance they give to accounting information for strategic and operational decision making, and considering the financial statements elaborated within the company or by an external accounting or consulting firm. Data were submitted to bivariate and multivariate statistical analyses. The results show that small firms' owners and/or managers confer more importance to accounting information for investment and operational decision making than for financing and dividends decision making. Moreover, the owners and/or managers give more importance to accounting

  3. Celulares: a emergência de um novo tipo de controle materno Cell phones: the emergence of a new king of materal control

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    Ana Maria Nicolaci-da-Costa

    2006-12-01

    Full Text Available Em uma pesquisa exploratória sobre o uso de celulares por jovens das camadas médias cariocas, entre 18 e 25 de idade, foi constatado que eles reclamavam muito que suas mães os controlavam ininterruptamente por meio de seus celulares. Para averiguar mais detalhadamente o que acontece entre mães e filhos dessa faixa etária, foi realizada uma segunda pesquisa. Nesta, foram entrevistadas 20 mães, também pertencentes às camadas médias cariocas, cujos filhos tinham perfil análogo ao dos jovens da primeira pesquisa. Para todas, a principal função dos celulares é abertamente a de controlar os filhos. Elas mostraram, no entanto, saber que há uma diferença entre o controle que vigorava quando eram jovens e aquele ao qual hoje submetem os filhos. Teorias contemporâneas sobre controle e vigilância de fato argumentam que houve uma substituição do controle normativo e coercitivo da modernidade pelo "ter conhecimento" do que se passa, característico da Era da Informação.An exploratory research on the use of cell phones by middle-class youngsters, ages 18 to 25, residing in Rio de Janeiro, revealed that they complained a great deal that their mothers controlled them unrelentingly by means of cell phones. To take a deeper look into what happens between mothers and children in this age group, a second investigation was carried out. Twenty middle-class mothers were interviewed, whose children's profile were analogous to that of the youngsters in the previous research. For all of the mothers, the main benefit of cell phones is to control their children. Nevertheless, they demonstrated to know that there's a difference between the control that they submit their children to from that that prevailed when they themselves were young. Contemporary control and surveillance theories, in fact, argue that the normative and coercive control of modernity has been replaced by "having knowledge" of what goes on, which is characteristic of the Information

  4. A reforma do setor elétrico no Brasil, Argentina e México: contrastes e perspectivas em debate

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    Alessandro André Leme

    2009-06-01

    Full Text Available A década de 1990 foi marcada por um movimento global de Reformas do Estado, principalmente nos países em desenvolvimento. Nesse processo, as orientações das agências multilaterais fizeram-se mais presentes. O conjunto de reformas liberalizantes transferiu para o setor privado setores até então em mãos do Estado. Dentre esses setores destacamos o caso da infra-estrutura energética. O setor elétrico no Brasil, na Argentina e no México consolidou-se após a II Guerra Mundial, sendo majoritariamente ligado ao Estado. Na década de 1990, nesses três países, esse setor passa por mudanças privatizantes. O quadro de fundo (plano político-econômico era muito similar entre os países, embora preservassem particularidades econômicas e político-institucionais. A crise de hiperinflação na década de 1980 e as fortes pressões dos organismos multilaterais para a realização de reformas para o mercado (privatização e flexibilização, dentre outros aspectos levou a mudanças no setor elétrico desses países. Partimos, neste trabalho, de uma abordagem histórico-estrutural e estratégica. Analisamos as reformas no setor elétrico brasileiro em diálogo com as ocorridas na Argentina e no México. Concluímos definindo as principais semelhanças e diferenças entre as políticas liberalizantes do setor elétrico no Brasil, Argentina e México e delimitamos os principais fatores dessas variações, ressaltando a não existência de unicidade histórica na escolhas de estratégias, mas sim composição de estratégias de desenvolvimento decorrentes do embate entre as diversas forças políticas presentes e atuantes num determinado espaço (Estado com suas variantes nacionais e internacionais.

  5. Nuclear physicist, arms control advocate

    CERN Multimedia

    Chang, K

    2002-01-01

    Victor F. Weisskopf, a nuclear physicist who worked on the Manhattan Project to build the first atomic bomb in World War II and later became an ardent advocate of arms control, died Monday at his home in Newton, MA, USA. He was 93 (1 page).

  6. Climate Control Using Nuclear Energy

    CERN Document Server

    Modgil, Moninder Singh

    2008-01-01

    We examine implications of anthropogenic low pressure regions, - created by injecting heat from nuclear reactors, into atmosphere. We suggest the possibility that such artificially generated low pressure regions, near hurricanes could disrupt their growth, path, and intensity. This method can also create controlled tropical stroms, which lead to substantial rainfall in arid areas, such as - (1)Sahara desert, (2) Australian interior desert, and (3) Indian Thar desert. A simple vortex suction model is developed to study, effect on atmospheric dynamics, by such a nuclear heat injection system.

  7. Intercomparison of activity measures of 1 {sup 31}I, {sup 67}Ga and {sup 201}Tl in nuclear medicine services in Recife/PE; Intercomparacao de medidas de atividade de {sup 131}I, {sup 67}Ga e {sup 201}Tl em servicos de medicina nuclear do Recife/PE

    Energy Technology Data Exchange (ETDEWEB)

    Couto, Iris Tairini V. do, E-mail: iristairini@hotmail.com [Instituto Federal de Educacao, Ciencia e Tecnologia de Pernambuco (IFPE), Recife, PE (Brazil); Fragoso, Maria da Conceicao de F.; Oliveira, Mercia Liane de, E-mail: mercial@cnen.gov.br [Centro Regional de Ciencias Nucleares do Nordeste (CRCN-NE/CNEN-PE), Recife, PE (Brazil)

    2013-07-01

    In this work, we intend to evaluate the performance of radionuclide calibrators of the Nuclear Medicine Services of the Recife (Brazil), the measurement procedures used by the professionals of these services and the frequency of the application of quality control testing required by Comissao Nacional de Energia Nuclear (CNEN) and the Agencia Nacional de Vigilancia Sanitaria (ANVISA), performing an intercomparison of radionuclides measurements.

  8. Current Situation of International Nuclear Arms Control and Nuclear Disarmament

    Institute of Scientific and Technical Information of China (English)

    Gong; Xianfu

    2014-01-01

    <正>Currently,international nuclear arms control and nuclear disarmament process is showing both encouraging and frustrating signs,with a stress on the latter.The following is a general picture:First,the new U.S.-Russian nuclear disarmament process faces challenges and prospect of a new round of nuclear disarmament negotiation is grim.As a result of implementing the New START signed in February 2011,as of March 1,2014,the United States has 1585

  9. Whither the legal control of nuclear energy?

    Energy Technology Data Exchange (ETDEWEB)

    Riley, Peter [Leicester School of Law (United Kingdom). Environmental Law Unit

    1995-12-31

    International nuclear trade is governed by the regime of legal control of nuclear energy, nuclear materials, knowledge of nuclear processes and weapons. Nuclear trade is under pinned by international agreements concerning physical protection and safeguards, the control of nuclear weapons, the protection of nuclear materials from terrorist action and third part liability. The political and geographical boundary changes of the past two years have significantly altered the background against which this regime has developed. Such changes have affected nuclear trade. The paper summarised the legal control of nuclear energy between States, identifies the areas of change which may affect this regime and the consequences for international trade. Conclusions are drawn as to the development of the international legal control of nuclear energy. (author). 21 refs.

  10. Relações Brasil-Argentina: a cooperação cultural como instrumento de integração regional

    Directory of Open Access Journals (Sweden)

    Raquel Paz dos Santos

    2009-12-01

    Full Text Available Este estudo desenvolve uma nova perspectiva das relações Brasil-Argentina a partir da análise de sua dimensão cultural entre os anos 1930-1954. Trata-se de mostrar como uma aproximação entre esses dois países foi incentivada através de projetos de cooperação intelectual, científica e artística, com o objetivo de desfazer imagens negativas e criar um sentimento de fraternidade entre brasileiros e argentinos. Com base na ideia de que uma maior cooperação contribuiria para o fortalecimento da região, e com o objetivo de alcançar uma futura integração econômica, essa prática também foi estimulada entre os demais países da América do Sul.

  11. Autonomous Control of Space Nuclear Reactors Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Nuclear reactors to support future robotic and manned missions impose new and innovative technological requirements for their control and protection instrumentation....

  12. Nuclear reactor kinetics and plant control

    CERN Document Server

    Oka, Yoshiaki

    2013-01-01

    Understanding time-dependent behaviors of nuclear reactors and the methods of their control is essential to the operation and safety of nuclear power plants. This book provides graduate students, researchers, and engineers in nuclear engineering comprehensive information on both the fundamental theory of nuclear reactor kinetics and control and the state-of-the-art practice in actual plants, as well as the idea of how to bridge the two. The first part focuses on understanding fundamental nuclear kinetics. It introduces delayed neutrons, fission chain reactions, point kinetics theory, reactivit

  13. The nuclear materials control technology briefing book

    Energy Technology Data Exchange (ETDEWEB)

    Hartwell, J.K.; Fernandez, S.J.

    1992-03-01

    As national and international interests in nuclear arms control and non-proliferation of nuclear weapons, intensify, it becomes ever more important that contributors be aware of the technologies available for the measurement and control of the nuclear materials important to nuclear weapons development. This briefing book presents concise, nontechnical summaries of various special nuclear material (SNM) and tritium production monitoring technologies applicable to the control of nuclear materials and their production. Since the International Atomic Energy Agency (IAEA) operates a multinational, on-site-inspector-based safeguards program in support of the Treaty on the Non-Proliferation of Nuclear Weapons (NPT), many (but not all) of the technologies reported in this document are in routine use or under development for IAEA safeguards.

  14. 78 FR 38739 - Special Nuclear Material Control and Accounting Systems for Nuclear Power Plants

    Science.gov (United States)

    2013-06-27

    ... COMMISSION Special Nuclear Material Control and Accounting Systems for Nuclear Power Plants AGENCY: Nuclear... nuclear material control and accounting system requirements for nuclear power plants. This guide applies... Nuclear Material Control and Accounting Systems for Nuclear Power Plants.'' ANSI N15.8-2009...

  15. 77 FR 28407 - Special Nuclear Material Control and Accounting Systems for Nuclear Power Plants

    Science.gov (United States)

    2012-05-14

    ... COMMISSION Special Nuclear Material Control and Accounting Systems for Nuclear Power Plants AGENCY: Nuclear...-5028, ``Special Nuclear Material Control and Accounting Systems for Nuclear Power Plants.'' In DG-5028... Control and Accounting Systems for Nuclear Power Plants.'' DATES: Submit comments by July 16,...

  16. Development and evaluation of Standard Operating Procedures (SOPs) for quality control tests and radiological protection activities in a Nuclear Medicine Service

    Energy Technology Data Exchange (ETDEWEB)

    Krempser, Alexandre R., E-mail: krempser@peb.ufrj.br [Universidade Federal do Rio de Janeiro (PEB/COPPE/UFRJ), RJ (Brazil). Programa de Engenharia Biomedica; Soares, Alexandre B. [Universidade Federal do Rio de Janeiro (IF/UFRJ), Rio de Janeiro, RJ (Brazil). Inst. de Fisica; Corbo, Rossana [Universidade Federal do Rio de Janeiro (FM/UFRJ), Rio de Janeiro, RJ (Brazil). Dept. de Radiologia

    2011-07-01

    The quality management in Nuclear Medicine Services is a requirement of national and international standards. The Brazilian regulatory agency in health surveillance, the Agencia Nacional de Vigilancia Sanitaria (ANVISA), in its Resolucao de Diretoria Colegiada (Collegiate Directory Resolution) no. 38, requires the elaboration of documents describing the technical and clinical routine activities. This study aimed to elaborate, implement and evaluate Standard Operating Procedures (SOPs) for quality control tests and radiological protection activities in the Nuclear Medicine Service of a university hospital. Eighteen SOPs were developed, involving tasks related to dose calibrator, gamma camera, Geiger-Muller detectors and radiological protection activities. The performance of its application was evaluated for a period of six months. It was observed a reduction in 75% of reported operational errors and 42% of the number of reported incidents with contamination by radioactive material. The SOPs were adequate and successful in its application. New procedures involving clinical activities will also be developed and evaluated. (author)

  17. Los cambios en el control de mando en las firmas según la teoría de agencia: una hipótesis para explicar el surgimiento del Sindicato Antioqueño Los cambios en el control de mando en las firmas según la teoría de agencia: una hipótesis para explicar el surgimiento del Sindicato Antioqueño

    Directory of Open Access Journals (Sweden)

    Diana Londoño Correa

    2005-12-01

    Full Text Available En este artículo se sintetizan los planteamientos de la teoría de agencia y se hace énfasis enla vertiente positivista de esta teoría, la cual muestra fortalezas para explicar el surgimientodel Sindicato Antioqueño, hoy llamado Grupo Empresarial Antioqueño (GEA, uno de losgrandes grupos económicos colombianos. En este trabajo se muestra cómo los intereses delos administradores de las empresas y de un grupo de los accionistas guiaron las actividadesque dieron como resultado el entrecruce de acciones entre empresas a partir del cual se hancoordinado las operaciones de un conjunto de sociedades con sede en Medellín. Este documentoes un subproducto de la investigación “Caracterización del centro corporativo del SindicatoAntioqueño” realizada en el marco de la Maestría en Ciencias de la Administración de laUniversidad EAFIT.This paper reviews the main aspects of the agency theory, and emphasizes on the positivist line, which shows strengths in explaining the birth of the Sindicato Antioqueño or the Grupo Empresarial Antioqueño (GEA, recognized as one of the largest Colombian economic groups. The main conclusion is that the managers’ interests as well as those of a group of shareholders where the ones pursued, and that in the process, cross ownership between the companies were established. This article is a result of the research “Characterization of the Sindicato Antioqueños´s Head Quarters”.

  18. Autonomous Control of Space Nuclear Reactors Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Nuclear reactors to support future lunar and Mars robotic and manned missions impose new and innovative technological requirements for their control and protection...

  19. Contributions of nuclear architecture to transcriptional control.

    Science.gov (United States)

    Stein, G S; van Wijnen, A J; Stein, J; Lian, J B; Montecino, M

    1995-01-01

    Three parameters of nuclear structure contribute to transcriptional control. The linear representation of promoter elements provides competency for physiological responsiveness within the contexts of development as well as cycle- and phenotype-dependent regulation. Chromatin structure and nucleosome organization reduce distances between independent regulatory elements providing a basis for integrating components of transcriptional control. The nuclear matrix supports gene expression by imposing physical constraints on chromatin related to three-dimensional genomic organization. In addition, the nuclear matrix facilitates gene localization as well as the concentration and targeting of transcription factors. Several lines of evidence are presented that are consistent with involvement of multiple levels of nuclear architecture in cell growth and tissue-specific gene expression during differentiation. Growth factor and steroid hormone responsive modifications in chromatin structure, nucleosome organization, and the nuclear matrix that influence transcription of the cell cycle-regulated histone gene and the bone tissue-specific osteocalcin gene during progressive expression of the osteoblast phenotype are considered.

  20. Multivariable Feedback Control of Nuclear Reactors

    Directory of Open Access Journals (Sweden)

    Rune Moen

    1982-07-01

    Full Text Available Multivariable feedback control has been adapted for optimal control of the spatial power distribution in nuclear reactor cores. Two design techniques, based on the theory of automatic control, were developed: the State Variable Feedback (SVF is an application of the linear optimal control theory, and the Multivariable Frequency Response (MFR is based on a generalization of the traditional frequency response approach to control system design.

  1. Autonomous Control of Nuclear Power Plants

    Energy Technology Data Exchange (ETDEWEB)

    Basher, H.

    2003-10-20

    A nuclear reactor is a complex system that requires highly sophisticated controllers to ensure that desired performance and safety can be achieved and maintained during its operations. Higher-demanding operational requirements such as reliability, lower environmental impacts, and improved performance under adverse conditions in nuclear power plants, coupled with the complexity and uncertainty of the models, necessitate the use of an increased level of autonomy in the control methods. In the opinion of many researchers, the tasks involved during nuclear reactor design and operation (e.g., design optimization, transient diagnosis, and core reload optimization) involve important human cognition and decisions that may be more easily achieved with intelligent methods such as expert systems, fuzzy logic, neural networks, and genetic algorithms. Many experts in the field of control systems share the idea that a higher degree of autonomy in control of complex systems such as nuclear plants is more easily achievable through the integration of conventional control systems and the intelligent components. Researchers have investigated the feasibility of the integration of fuzzy logic, neural networks, genetic algorithms, and expert systems with the conventional control methods to achieve higher degrees of autonomy in different aspects of reactor operations such as reactor startup, shutdown in emergency situations, fault detection and diagnosis, nuclear reactor alarm processing and diagnosis, and reactor load-following operations, to name a few. With the advancement of new technologies and computing power, it is feasible to automate most of the nuclear reactor control and operation, which will result in increased safety and economical benefits. This study surveys current status, practices, and recent advances made towards developing autonomous control systems for nuclear reactors.

  2. Nuclear propulsion control and health monitoring

    Science.gov (United States)

    Walter, P. B.; Edwards, R. M.

    1993-01-01

    An integrated control and health monitoring architecture is being developed for the Pratt & Whitney XNR2000 nuclear rocket. Current work includes further development of the dynamic simulation modeling and the identification and configuration of low level controllers to give desirable performance for the various operating modes and faulted conditions. Artificial intelligence and knowledge processing technologies need to be investigated and applied in the development of an intelligent supervisory controller module for this control architecture.

  3. Retención de clientes en agencias de eventos

    Directory of Open Access Journals (Sweden)

    Claudia Gómez-Ramírez

    2011-01-01

    Full Text Available Como componente de la mezcla de comunicación efectiva para las marcas se encuentran los "Eventos", que hoy en día exigen una gestión estratégica. Resulta clave, para las organizaciones especializadas en la prestación de este servicio, aplicar herramientas que les permitan ser competitivas a largo plazo gracias a la diferenciación. Para ello, el CESA ha estudiado la relación cliente-agencia de comunicación de marketing, fundamentalmente respecto a la importancia de la retención de clientes en relaciones B2B, como las que se llevan a cabo entre agencias de eventos y sus clientes. En el presente artículo se exponen los principales hallazgos de una investigación de tipo exploratorio acerca del tema de retención de clientes, que incluye perfiles, elementos claves para la satisfacción y factores relevantes de la relación clienteagencia de eventos como elementos fundamentales de la gestión empresarial. Al tener un mayor conocimiento del perfil de los clientes, las agencias podrán ser más productivas y competitivas, pues estarán en capacidad de ofrecer iniciativas de servicios con características particulares.

  4. "Mater puerorum'. A medieval naming for an enigmatic children's disease.

    Science.gov (United States)

    Kottek, S S

    1981-09-01

    The pediatric clinical entity called "Mater Puerorum' appears first in the latin translation of Rhazes' "Practica Puerorum' and in his "Continens'. His descriptions of the disease could give some likeness either to a diagnosis of night terrors, or of hyperpyretic convulsions, or of a slight form of epilepsy. Mater Puerorum is afterwards described by most pediatric authors till the Renaissance period without much originality. Rhazes being one of their main sources anyway. Mater Puerorum has been considered by Still and Radbill as a synonym for hysterical fits in children. Going back to the Arabic original naming: Ummu's Sibyan, we venture another etymology based on Babylonian-Judeo-Arabic demonology. The "Mother of the Children' could be the female demon Karina--or Lilith--which is said to come to plague the children at night. The naming Mater Puerorum could thus be ascribed to a folklore origin, rather than to hysteria.

  5. Controlled Nuclear Fusion: Status and Outlook

    Science.gov (United States)

    Rose, David J.

    1971-01-01

    Presents the history, current concerns and potential developments of nuclear fusion as a major energy source. Controlled fusion research is summarized, technological feasibility is discussed and environmental factors are examined. Relationships of alternative energy sources as well as energy utilization are considered. (JM)

  6. Reactivity control assembly for nuclear reactor. [LMFBR

    Science.gov (United States)

    Bollinger, L.R.

    1982-03-17

    This invention, which resulted from a contact with the United States Department of Energy, relates to a control mechanism for a nuclear reactor and, more particularly, to an assembly for selectively shifting different numbers of reactivity modifying rods into and out of the core of a nuclear reactor. It has been proposed heretofore to control the reactivity of a breeder reactor by varying the depth of insertion of control rods (e.g., rods containing a fertile material such as ThO/sub 2/) in the core of the reactor, thereby varying the amount of neutron-thermalizing coolant and the amount of neutron-capturing material in the core. This invention relates to a mechanism which can advantageously be used in this type of reactor control system.

  7. Agencias gubernamentales internacionales y orientación de carreras

    OpenAIRE

    Conger, Stuart

    1999-01-01

    La OCDE (Organización Internacional para Cooperación Económica y Desarrollo), como muchas organizaciones internacionales y nacionales que tienen que ver con el desarrollo económico, cree que la orientación para la carrera tiene un rol importante para promover el desarrollo de los recursos humanos de un país. Generalmente las agencias de desarrollo económico siempre recomiendan que los servicios de orientación para la carrera sean fortalecidos. Sin embargo, con demasiada frecuencia no reconoce...

  8. Optimization Algorithms for Nuclear Reactor Power Control

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Yeong Min; Oh, Won Jong; Oh, Seung Jin; Chun, Won Gee; Lee, Yoon Joon [Jeju National University, Jeju (Korea, Republic of)

    2010-10-15

    One of the control techniques that could replace the present conventional PID controllers in nuclear plants is the linear quadratic regulator (LQR) method. The most attractive feature of the LQR method is that it can provide the systematic environments for the control design. However, the LQR approach heavily depends on the selection of cost function and the determination of the suitable weighting matrices of cost function is not an easy task, particularly when the system order is high. The purpose of this paper is to develop an efficient and reliable algorithm that could optimize the weighting matrices of the LQR system

  9. Annual report 2013 - ABACC - Brazilian-Argentina agency for accounting and control of nuclear materials; Relatorio anual 2013 - ABACC - Agencia Brasileiro-Argentina de Contabilidade e Controle de Materiais Nucleares

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2013-07-01

    The document reports the activities of the commission and all technical activities. Shows the presence of ABACC at events; the strengthening technical capability; technical cooperation, institutional and administrative and financial activities; an outlook for 2014. Gives a list of the ABACC inspectors and presents the facilities under the Quadripartite Agreement.

  10. The control of nuclear sector; Le controle du nucleaire

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-07-01

    The Asn is loaded with the control of the nuclear safety and the radiation protection in France: it provides this control, in the name of the state, to protect the workers, the patients, the public and the environment of the risks in relation with nuclear activities. The control is the core business of Asn. Asn so checks the nuclear basic installations (I.N.B.), since their conception until their dismantling, the pressure equipment specially conceived for these installations, the management of the radioactive waste as well as the transport of radioactive substances. Asn also checks all the industrial and research installations as well as the hospitals where are used ionizing radiations. It is a more recent profession there, because dating the reform of the control of the nuclear power of 2002, which constitutes that of the radiation protection. The first responsibility of the activities at risks falls to the one who begins them. This principle applies to all the sectors checked by Asn: an industrialist is responsible for the safety of the nuclear installations which he exploits, a doctor is responsible for the use of the ionizing radiations which he uses. (N.C.)

  11. Nuclear thermal rocket engine operation and control

    Science.gov (United States)

    Gunn, Stanley V.; Savoie, Margarita T.; Hundal, Rolv

    1993-06-01

    The operation of a typical Rover/Nerva-derived nuclear thermal rocket (NTR) engine is characterized and the control requirements of the NTR are defined. A rationale for the selection of a candidate diverse redundant NTR engine control system is presented and the projected component operating requirements are related to the state of the art of candidate components and subsystems. The projected operational capabilities of the candidate system are delineated for the startup, full-thrust, shutdown, and decay heat removal phases of the engine operation.

  12. Complete Genome Sequence of Bacillus megaterium Myophage Mater

    OpenAIRE

    Lancaster, Jacob C.; Hodde, Mary K.; Hernandez, Adriana C.; Kuty Everett, Gabriel F.

    2015-01-01

    Bacillus megaterium is a ubiquitous, soil inhabiting Gram-positive bacterium that is a common model organism and is used in industrial applications for protein production. The following reports the complete sequencing and annotation of the genome of B. megaterium myophage Mater and describes the major features identified.

  13. The Labour Market Effects of "Alma Mater": Evidence from Italy

    Science.gov (United States)

    Brunello, Giorgio; Cappellari, Lorenzo

    2008-01-01

    We use data from a nationally representative survey of Italian graduates to study whether "Alma Mater" matters for employment and earnings 3 years after graduation. We find that the attended college matters, and that there are important college-related differences, both among and within regions of the country. These differences, however,…

  14. Collective control of a nuclear reactor

    Energy Technology Data Exchange (ETDEWEB)

    Rognin, L.

    1995-06-01

    Nowadays, mainly related to the increasing complexity of working environments, working activities become more and collective. The present research on the paradoxical nature of working teams, considered from a reliability point of view. This document is composed of four Sections. The first Section introduces the context of the research, its objectives and the underlying assumptions. In the second Section, we describe a working situation, which is the control of a nuclear reactor. Relations between cooperative work and reliability are discussed in the third Section. Finally, in the fourth Section, a synthesis of the research and some perspectives are proposed. (authors). 7 refs.

  15. Collagen-inspired self-assembling materals

    NARCIS (Netherlands)

    Skrzeszewska, P.J.

    2011-01-01

      The rapid increase of the quality of life together with the progress of medical science asks for the development of new, tuneable and controllable materials. For the same reason, materials used for biomedical applications have to be increasingly biocompatible, biodegradable and biofunctional

  16. Ránking de anuncios y agencias de publicidad en Venezuela

    Directory of Open Access Journals (Sweden)

    Estela Núñez Barriopedro

    2015-01-01

    Full Text Available El objetivo de este trabajo es realizar un análisis de la posición actual de las agencias de publicidad venezolanas y de sus anuncios en el UNIR (Uni- versidad Internacional de la Rioja Ranking Iberoamericano de Publicidad. Asimismo, se estudia la tendencia de sus posiciones y se realiza una clasifica- ción de agencias y anuncios en cuartiles según su posición y puntuación en el ranking. Para el caso de Venezuela, se analiza el ranking de anuncios en 2012-2013 y el ranking de agencias en 2014-2015 para una muestra total de 2.130 y 2.175 anuncios, 775 y 538 agencias respectivamente en Iberoamérica.

  17. Plasma Physics and Controlled Nuclear Fusion

    CERN Document Server

    Miyamoto, Kenro

    2005-01-01

    The primary objectives of this book are, firstly, to present the essential theoretical background needed to understand recent fusion research and, secondly, to describe the current status of fusion research for graduate students and senior undergraduates. It will also serve as a useful reference for scientists and engineers working in the related fields. In Part I, Plasma Physics, the author explains the basics of magneto-hydrodynamics and kinetic theory in a simple and compact way and, at the same time, covers important new topics for fusion studies such as the ballooning representation, instabilities driven by energetic particles and various plasma models for computer simulations. Part II, Controlled Nuclear Fusion, attempts to review the "big picture" in fusion research. All important phenomena and technologies are addressed, with a particular emphasis on the topics of most concern in current research.

  18. Análise de práticas contabilísticas na antiga civilização mesopotâmica = Analysis of accounting practices in the former mesopotamian Civilization

    Directory of Open Access Journals (Sweden)

    Miguel Gonçalves

    2010-01-01

    Full Text Available Constitui um facto perfeitamente verificável que nas últimas décadas se tem vindo a dedicar umaatenção crescente a trabalhos em História da Contabilidade. Antes dos estudos consideradoshoje como fazendo parte da Nova História da Contabilidade, os historiadores da nossa disciplinaconsagraram as suas investigações a aspectos relacionados com a origem e os processosevolutivos da Contabilidade, particularmente no que toca ao exame de práticas contabilísticas emcivilizações antigas. Com base na revisão da literatura de autores não-contabilísticos econtabilísticos (principalmente aqueles que se podem classificar como historiadoresconvencionais da Contabilidade, a questão magna que versamos neste trabalho respeita ànarração resumida de algumas técnicas contabilísticas praticadas no seio da mais antigacivilização da humanidade - a Mesopotâmia.It is a perfectly verifiable fact that in recent decades increasing attention has been devoting to works inAccounting History. Before studies considered today as part of the New Accounting History, historiansof our discipline dedicated their research to aspects on the origin and evolutionary processes ofAccounting, particularly with regard to the examination of accounting practices in ancient civilizations.Based on the review of the literature of non-accounting and Accounting authors, mainly those that canbe classified as conventional Accounting historians, the broader issue discussed in this work thusrelates to the narrative summary of some accounting techniques practiced within the most ancientcivilization of mankind - Mesopotamia.

  19. ANÁLISIS DEL SECTOR DE LAS AGENCIAS DE VIAJES EN ESPAÑA: UNA APROXIMACIÓN DESDE LA CARACTERIZACIÓN DEL SECTOR ENTRE LAS AGENCIAS DE VIAJES TRADICIONALES Y LAS AGENCIAS DE VIAJES ONLINE

    Directory of Open Access Journals (Sweden)

    Luis Lacalle Muñoz

    2013-06-01

    Full Text Available El sector de las agencias de viajes español está sufriendo en los últimos años una importantísima transformación. El número de agencias se ha visto reducido de manera drástica y la composición de la industria también se ha visto alterada. Por otra parte, cada vez es mayor el número de agencias online que desplazan a aquellas que realizan su labor de intermediación de una manera tradicional. No sólo en número sino también atendiendo a la cuota de mercado. El presente artículo además de presentar una aproximación al criterio de división entre agencias tradicionales y online, ofrece una perspectiva de la actual composición y reciente evolución del sector.

  20. CAPACIDAD DE AGENCIA DE AUTOCUIDADO EN LAS PERSONAS ADULTAS QUE PADECEN ARTRITIS REUMATOIDE

    Directory of Open Access Journals (Sweden)

    Viriam Leiva Díaz

    2012-04-01

    Full Text Available El objetivo de la investigación consistió en analizar la capacidad de agencia de autocuidado que poseen laspersonas con diagnóstico de artritis reumatoide, quienes habitan en los cantones de Palmares y San Ramón. Se desarrolló una metodología de investigación cuantitativa de tipo descriptiva transversal. En cuanto a la población participante del estudio, estuvo conformada por 13 personas diagnosticadas con artritis reumatoide; respecto de los instrumentos utilizados para recolectar información, a los colaboradores se les aplicó el instrumento “Escala de apreciación de la capacidad de agencia de autocuidado”, propuesta por Dorothea Orem. Se determinó que los participantes poseen alta capacidad de agencia de autocuidado en las diferentes categorías, ya que únicamente se detectó baja capacidad de agencia de autocuidado en cuanto a interacción social (2 personas, y respecto del consumo insuficiente de alimentos (5 personas. La escala ASA permite a la Enfermera (o determinar la capacidad de agencia de autocuidado, de forma oportuna y eficaz. Además, permitió a las investigadoras observar un panorama general de las necesidades de autocuidado de la población participante y constatar que esta presenta alta capacidad de agencia de autocuidado.

  1. Thrust Vector Control for Nuclear Thermal Rockets

    Science.gov (United States)

    Ensworth, Clinton B. F.

    2013-01-01

    Future space missions may use Nuclear Thermal Rocket (NTR) stages for human and cargo missions to Mars and other destinations. The vehicles are likely to require engine thrust vector control (TVC) to maintain desired flight trajectories. This paper explores requirements and concepts for TVC systems for representative NTR missions. Requirements for TVC systems were derived using 6 degree-of-freedom models of NTR vehicles. Various flight scenarios were evaluated to determine vehicle attitude control needs and to determine the applicability of TVC. Outputs from the models yielded key characteristics including engine gimbal angles, gimbal rates and gimbal actuator power. Additional factors such as engine thrust variability and engine thrust alignment errors were examined for impacts to gimbal requirements. Various technologies are surveyed for TVC systems for the NTR applications. A key factor in technology selection is the unique radiation environment present in NTR stages. Other considerations including mission duration and thermal environments influence the selection of optimal TVC technologies. Candidate technologies are compared to see which technologies, or combinations of technologies best fit the requirements for selected NTR missions. Representative TVC systems are proposed and key properties such as mass and power requirements are defined. The outputs from this effort can be used to refine NTR system sizing models, providing higher fidelity definition for TVC systems for future studies.

  2. Relación de agencia y monopolio. El caso del tabaco en España (1887-1986

    Directory of Open Access Journals (Sweden)

    Eva Chamorro

    2016-01-01

    Full Text Available Los análisis históricos contables permiten evidenciar, bajo el marco de la teoría de la agencia, los conflictos de intereses que se producen en una organización. Nuestro objetivo, con un estudio longitudinal, basado en fuentes primarias, es comprobar cómo se regula una relación de agencia a través de contratos formales, y el papel que asume la contabilidad. El caso en el que nos basamos, y que puede ser una importante contribución en ese sentido, es el del arrendamiento del monopolio estatal del tabaco a una empresa privada, desde el inicio de la gestión (1887 hasta que empieza a desaparecer esta actividad monopolística (1986. Nuestros hallazgos ponen de manifiesto que los contratos establecidos permiten un gran control del principal sobre el agente y que no se cumplen todas las condiciones que deben darse para considerarlos «un buen acuerdo contractual». Por otro lado, la contabilidad aparece como un instrumento clave para el control del Estado sobre las empresas arrendatarias. Nuestra principal conclusión es que el agente es quien asume mayor riesgo en el arrendamiento, y el principal mantiene un comportamiento oportunista durante todo el periodo, lo que contradice los planteamientos más generalizados de la teoría y permite relajar sus asunciones iniciales.

  3. 小儿外科手术中行丙泊酚靶控加单次硬膜的效果探究%Effect exploration of implementation of propofol target control plus one-time dura mater in pediatric surgery

    Institute of Scientific and Technical Information of China (English)

    时文俊

    2014-01-01

    Objective To investigate the implementation effect of propofol target control plus one-time dura mater in pediatric surgery. Methods Eighty children who received surgical treatment in our hospital from September 2012 to January 2014 were selected as the study subjects and randomly and evenly divided into the study group and the control group, which received one-time epidural plus propofol target control and ketamine anesthesia respectively. The patients' blood pressure, heart rate, oxyhemoglobin saturation, physical tamper, muscle relaxation and other indicators of the two groups in different time periods were compared. Results In the control group, the blood pressure and heart rates at the beginning of surgery and at the end of surgery increased significantly compared to the blood pressure and heart rate before surgery(P < 0.05), and in the study group, the blood pressure did not change significantly, but it was lower than that of the control group in the corresponding period, with statistically significant difference(P<0.05). In the study group, the heart rates at the beginning of surgery and at the end of surgery reduced significantly compared to the heart rate before surgery(P<0.05) and reduced a lot compared to the heart rate of the control group in the corresponding period(P<0.05). The study group had less physical tamper and shorter awakening time, with statistically significant differences(P < 0.05). Conclusion In pediatric surgery, the implementation of propofol target control plus one-time dura mater does not have large influence on the children's respiratory circulation and has the features of good effect, fast awakening and safety.%目的:探究在小儿外科手术中行丙泊酚靶控加单次硬膜的效果。方法选取2012年9月~2014年1月来本院接受手术治疗的80例患儿作为研究对象,随机等分为研究组和对照组,分别为单次硬膜外加丙泊酚靶控和氯胺酮麻醉,比较不同时间段的两组患者血

  4. Closed loop control of the sawtooth instability in nuclear fusion

    NARCIS (Netherlands)

    Witvoet, G.; Steinbuch, M.; Westerhof, E.; Doelman, N.J.; Baar, M.R. de

    2010-01-01

    In nuclear fusion the sawtooth instability is an important plasma phenomenon, having both positive and negative effects on the tokamak plasma. Control of its period is essential in future nuclear fusion reactors. This paper presents a control oriented model of the sawtooth instability, with current

  5. Nuclear Forensic Science: Analysis of Nuclear Material Out of Regulatory Control

    Science.gov (United States)

    Kristo, Michael J.; Gaffney, Amy M.; Marks, Naomi; Knight, Kim; Cassata, William S.; Hutcheon, Ian D.

    2016-06-01

    Nuclear forensic science seeks to identify the origin of nuclear materials found outside regulatory control. It is increasingly recognized as an integral part of a robust nuclear security program. This review highlights areas of active, evolving research in nuclear forensics, with a focus on analytical techniques commonly employed in Earth and planetary sciences. Applications of nuclear forensics to uranium ore concentrates (UOCs) are discussed first. UOCs have become an attractive target for nuclear forensic researchers because of the richness in impurities compared to materials produced later in the fuel cycle. The development of chronometric methods for age dating nuclear materials is then discussed, with an emphasis on improvements in accuracy that have been gained from measurements of multiple radioisotopic systems. Finally, papers that report on casework are reviewed, to provide a window into current scientific practice.

  6. El efecto de los conflictos de agencia en las políticas de dividendos a los accionistas. El caso chileno

    Directory of Open Access Journals (Sweden)

    Fernando Lefort

    2008-01-01

    Full Text Available En este articulo investigo los coeficientes (ratios de pago de dividendos de las compañías chilenas pueden explicarse por el grado de los conflictos potenciales de agencia entre los accionistas minoritarios y los que controlan la empresa. Utilizo el análisis de regresión de un panel de datos y un estudio de hechos para someter a prueba diferentes hipótesis relacionadas con el afecto de la gestión empresarial en las políticas de pago a los accionistas.Los resultados muestran que en el contexto de una economía emergente, como la chilena, que presenta una alta concentración de la propiedad y una extendida utilización de conglomerados y estructuras piramidales, la teoría de la búsqueda de la renta para explicar los efectos de los problemas de agencia en las políticas de pago de dividendos parecen ser en particular pertinentes. Las compañías que presentan un grado mas alto de coincidencia entre los derechos de flujo de efectivo y los derechos de control tienden a tener políticas de dividendos mas generosas. Por otra parte, los anuncios de dividendos inesperadamente altos que hacen compañías con un potencial mayor de conflictos de agencia presentan rendimientos anormalmente altos.

  7. Regulatory control of nuclear safety in Finland. Annual report 1997

    Energy Technology Data Exchange (ETDEWEB)

    Tossavainen, K. [ed.

    1998-08-01

    The report describes regulatory control of the use of nuclear energy by the Radiation and Nuclear Safety Authority (STUK) in Finland in 1997. Nuclear regulatory control ascertained that the operation of Finnish NPPs was in compliance with the conditions set out in operating licences and current regulations. In addition to NPP normal operation, STUK oversaw projects at the plant units relating to power uprating and safety improvements. STUK prepared statements for the Ministry of Trade and Industry about the applications for renewing the operating licenses of Loviisa and Olkiluoto NPPs. The most important items of supervision in nuclear waste management were studies relating to the final disposal of spent fuel from NPPs and the review of the licence application for a repository for low- and intermediate-level reactor waste from Loviisa NPP. Preparation of general safety regulations for the final disposal of spent nuclear fuel, to be published in the form of a Council of State Decision, was started. By safeguards control, the use of nuclear materials was verified to be in compliance with current regulations and that the whereabouts of every batch of nuclear material were always known. Nuclear material safeguards were stepped up to prevent illicit trafficking of nuclear materials and other radioactive materials. In co-operation with the Ministry for Foreign Affairs and the Institute of Seismology (University of Helsinki), preparations were undertaken to implement the Comprehensive Nuclear Test Ban Treaty (CTBT). For enforcement of the Treaty and as part of the international regulatory approach, STUK is currently developing laboratory analyses relating to airborne radioactivity measurements. The focus of co-operation funded by external sources was as follows: improvement of the safety of Kola and Leningrad NPPs, improvement of nuclear waste management in North-West Russia, development of the organizations of nuclear safety authorities in Eastern Europe and development

  8. Cavernous hemangioma of the dura mater mimicking meningioma

    Science.gov (United States)

    Di Vitantonio, Hambra; De Paulis, Danilo; Ricci, Alessandro; Marzi, Sara; Dehcordi, Soheila Raysi; Galzio, Renato Juan

    2015-01-01

    Background: Cavernomas are benign lesions that most commonly occur intra-parenchymally, but occasionally they have been described as arising from the dura mater. Extra-axial cavernous angiomas (or hemangiomas) account for 0.4–2% of all intracranial vascular malformations, and they usually occur in the middle cranial fossa, associated with the cavernous sinus. Other possible localizations (e.g. tentorium, convexity, anterior cranial fossa, cerebellopontine angle, Meckel's cave, sella turcica and internal auditory meatus) are rare, and they account only for 0.2–0.5%. Case Description: We report a case of a 30-year-old female presenting with a 2 years history of headache unresponsive to drug therapy. The magnetic resonance imaging showed a dural-based lesion in the left frontal region; the lesion size was: 1.5 cm × 3.5 cm. The appearance suggested a convexity meningioma. A left frontal craniotomy was performed, and the histopathological diagnosis deposed for a cavernous hemangioma of the dura mater. The follow-up at 1-year was good without any neurologic deficit. Conclusions: Dural-based cavernous hemangiomas of the convexity are uncommon lesions. Up to now, only 13 cases have been described in the literature. The authors have discussed clinical aspects, radiological features, surgical treatment, and operative findings. PMID:26421218

  9. Ética policial: una aproximación desde la agencia*

    Directory of Open Access Journals (Sweden)

    Nidian Johana Sanabria Cárdena

    2012-07-01

    Full Text Available El presente texto se propone mostrar la posibilidad de la agencia desde un curso de ética en el marco de la formación ejecutiva del cuerpo policial. Se partede los avances logrados en las discusiones sobre el concepto de agencia, en particular en la sociología norteamericana. Seguido, se procede a presentar las prácticas desarrolladas con los estudiantes, con el propósito de sugerir posibilidades para dicha agencia desde sí mismos. Y finalmente, se reflexiona sobre las posibilidades de que esta propuesta pueda resultar útil en el desarrollo institucional de la Policía Nacional de Colombia.

  10. U.S. national nuclear material control and accounting system

    Energy Technology Data Exchange (ETDEWEB)

    Taylor, S; Terentiev, V G

    1998-12-01

    Issues related to nuclear material control and accounting and illegal dealing in these materials were discussed at the April 19--20, 1996 Moscow summit meeting (G7 + Russia). The declaration from this meeting reaffirmed that governments are responsible for the safety of all nuclear materials in their possession and for the effectiveness of the national control and accounting system for these materials. The Russian delegation at this meeting stated that ''the creation of a nuclear materials accounting, control, and physical protection system has become a government priority''. Therefore, in order to create a government nuclear material control and accounting system for the Russian Federation, it is critical to study the structure, operating principles, and regulations supporting the control and accounting of nuclear materials in the national systems of nuclear powers. In particular, Russian specialists have a definite interest in learning about the National Nuclear Material Control and Accounting System of the US, which has been operating successfully as an automated system since 1968.

  11. Teoría de la agencia y sus aplicaciones en el mercadeo

    Directory of Open Access Journals (Sweden)

    Yuri Gorbaneff

    2001-12-01

    Full Text Available La teoría de la Agencia Principal, TAP, permite mejorar nuestra comprensión de la empresa, especialmente en el área de mercadeo. Se utiliza como una plataforma conceptual para modelar situaciones en las aéreas de administración del personal de mercadeo, en el manejo de los canales y en las relaciones entre proveedores y clientes. Por su parte, el dominio de la teoría de juegos no es un requisito sine qua non para poder utilizar la teoría de la agencia y modelar las situaciones concretas.

  12. Agencia de autocuidado y adherencia al tratamiento en personas con factores de riesgo cardiovascular

    OpenAIRE

    Velandia-Arias, Anita; Rivera-Álvarez, Luz N.

    2013-01-01

    Objetivo Se determino la relación existente entre la Agencia de autocuidado con la adherencia al tratamiento farmacológico y no farmacológico  en pacientes con algún factor de riesgo cardiovascular del programa de crónicos del  hospital Tunjuelito.  Métodos Diseño descriptivo correlacional que midió y relacionó la Agencia de autocuidado y la Adherencia a los tratamientos en una muestra de 201 personas que contaban con algún factor de riesgo cardiovascular: Obesidad, Sedentarismo, Hipertensión...

  13. PPARs: Nuclear Receptors Controlled by, and Controlling, Nutrient Handling through Nuclear and Cytosolic Signaling

    Directory of Open Access Journals (Sweden)

    Maria Moreno

    2010-01-01

    Full Text Available Peroxisome proliferator-activated receptors (PPARs, which are known to regulate lipid homeostasis, are tightly controlled by nutrient availability, and they control nutrient handling. In this paper, we focus on how nutrients control the expression and action of PPARs and how cellular signaling events regulate the action of PPARs in metabolically active tissues (e.g., liver, skeletal muscle, heart, and white adipose tissue. We address the structure and function of the PPARs, and their interaction with other nuclear receptors, including PPAR cross-talk. We further discuss the roles played by different kinase pathways, including the extracellular signal-regulated kinases/mitogen-activated protein kinase (ERK MAPK, AMP-activated protein kinase (AMPK, Akt/protein kinase B (Akt/PKB, and the NAD+-regulated protein deacetylase SIRT1, serving to control the activity of the PPARs themselves as well as that of a key nutrient-related PPAR coactivator, PPARγ coactivator-1α (PGC-1α. We also highlight how currently applied nutrigenomic strategies will increase our understanding on how nutrients regulate metabolic homeostasis through PPAR signaling.

  14. Sensitive Magnetic Control of Ensemble Nuclear Spin Hyperpolarisation in Diamond

    CERN Document Server

    Wang, Hai-Jing; Avalos, Claudia E; Seltzer, Scott J; Budker, Dmitry; Pines, Alexander; Bajaj, Vikram S

    2012-01-01

    Dynamic nuclear polarisation, which transfers the spin polarisation of electrons to nuclei, is routinely applied to enhance the sensitivity of nuclear magnetic resonance; it is also critical in spintronics, particularly when spin hyperpolarisation can be produced and controlled optically or electrically. Here we show the complete polarisation of nuclei located near the optically-polarised nitrogen-vacancy (NV) centre in diamond. When approaching the ground-state level anti-crossing condition of the NV electron spins, 13C nuclei in the first-shell are polarised in a pattern that depends sensitively and sharply upon the magnetic field. Based on the anisotropy of the hyperfine coupling and of the optical polarisation mechanism, we predict and observe a complete reversal of the nuclear spin polarisation with a few-mT change in the magnetic field. The demonstrated sensitive magnetic control of nuclear polarisation at room temperature will be useful for sensitivity-enhanced NMR, nuclear-based spintronics, and quant...

  15. Nuclear electric power safety, operation, and control aspects

    CERN Document Server

    Knowles, J Brian

    2013-01-01

    Assesses the engineering of renewable sources for commercial power generation and discusses the safety, operation, and control aspects of nuclear electric power From an expert who advised the European Commission and UK government in the aftermath of Three Mile Island and Chernobyl comes a book that contains experienced engineering assessments of the options for replacing the existing, aged, fossil-fired power stations with renewable, gas-fired, or nuclear plants. From geothermal, solar, and wind to tidal and hydro generation, Nuclear Electric Power: Safety, Operation, and Control Aspects ass

  16. Regulatory control of nuclear safety in Finland. Annual report 1999

    Energy Technology Data Exchange (ETDEWEB)

    Tossavainen, K. [ed.

    2000-06-01

    This report concerns the regulatory control of nuclear energy in Finland in 1999. Its submission to the Ministry of Trade and Industry by the Finnish Radiation and Nuclear Safety Authority (STUK) is stipulated in section 121 of the Nuclear Energy Decree. STUK's regulatory work was focused on the operation of the Finnish nuclear power plants as well as on nuclear waste management and safeguards of nuclear materials. The operation of the Finnish nuclear power plants was in compliance with the conditions set out in their operating licences and with current regulations, with the exception of some inadvertent deviations from the Technical Specifications. No plant events endangering the safe use of nuclear energy occurred. The individual doses of all nuclear power plant workers remained below the dose threshold. The collective dose of the workers was low, compared internationally, and did not exceed STUK's guidelines at either nuclear power plant. The radioactive releases were minor and the dose calculated on their basis for the most exposed individual in the vicinity of the plant was well below the limit established in a decision of the Council of State at both Loviisa and Olkiluoto nuclear power plants. STUK issued statements to the Ministry of Trade and Industry about the environmental impact assessment programme reports on the possible nuclear power plant projects at Olkiluoto and Loviisa and about the continued operation of the research reactor in Otaniemi, Espoo. A Y2k-related safety assessment of the Finnish nuclear power plants was completed in December. In nuclear waste management STUK's regulatory work was focused on spent fuel storage and final disposal plans as well as on the treatment, storage and final disposal of reactor waste. No events occurred in nuclear waste management that would have endangered safety. A statement was issued to the Ministry of Trade and Industry about an environmental impact assessment report on a proposed final

  17. Educação e hegemonia na América Latina de hoje: projetos de sociedade e de educação nos anos 90: Brasil, Argentina, Chile e Venezuela

    Directory of Open Access Journals (Sweden)

    Adriana Almeida Sales de Melo

    2000-01-01

    Full Text Available Iniciada em março de 1999, esta pesquisa está se desenvolvendo como elemento de meu doutorado em educação. Este trabalho também faz parte do Projeto CORI/MERCOSUL, área temática Educação, desde 1999. Esta investigação tem como tema central a relação entre os diversos projetos de sociedade e de educação dos principais sujeitos políticos coletivos que planejam e atuam na direção atual das políticas educacionais dos países da América Latina. Pretendemos analisar o processo de transição e consolidação democrática do Brasil, Argentina, Chile e Venezuela; bem como o redirecionamento das políticas educacionais nestes ambientes culturais, no sentido de esclarecer as contradições entre as demandas e objetivos dos sujeitos políticos coletivos locais e internacionais em seu movimento de construção de um projeto hegemônico de sociedade e de educação; ora neoliberal, ora democrático de massas. Este tipo de análise pode trazer contribuições reais no sentido da construção e sistematização de elementos de integração entre as diversas identidades históricas e culturais dos nossos países; interferindo sob a forma de novas categorias de investigação, no nosso planejamento e ação educacionais locais. Started in 1999, march, this research is going on as an element of my education doctorate. This work is also part of CORI/MERCOSUL project, at education thematic area, since 1999. This investigation has as central theme the relation between "society and education projects" of the principal politician social subjects that plan and actuate in the actual educational policies directions at Latin America countries. We intend to analyze the democratic transition and consolidation in Brazil, Argentina, Chile and Venezuela; and also the educational policies redirections in these cultural ambiance; in the way to clarify the contradictions between these social subjects demands and objectives in their building process of "society

  18. Control of nuclear organization by F-actin binding proteins.

    Science.gov (United States)

    Pfisterer, Karin; Jayo, Asier; Parsons, Maddy

    2017-01-06

    The regulation of nuclear shape and deformability is a key factor in controlling diverse events from embryonic development to cancer cell metastasis, but the mechanisms governing this process are still unclear. Our recent study demonstrated an unexpected role for the F-actin bundling protein fascin in controlling nuclear plasticity through a direct interaction with Nesprin-2. Nesprin-2 is a component of the LINC complex that is known to couple the F-actin cytoskeleton to the nuclear envelope. We demonstrated that fascin, which is predominantly associated with peripheral F-actin rich filopodia, binds directly to Nesprin-2 at the nuclear envelope in a range of cell types. Depleting fascin or specifically blocking the fascin-Nesprin-2 complex leads to defects in nuclear polarization, movement and cell invasion. These studies reveal a novel role for an F-actin bundling protein in control of nuclear plasticity and underline the importance of defining nuclear-associated roles for F-actin binding proteins in future.

  19. Comportamientos y capacidad de agencia de autocuidado de adultos con insuficiencia cardiaca

    Directory of Open Access Journals (Sweden)

    EDITH ARREDONDO HOLGUÍN

    2010-06-01

    Full Text Available Este estudio tiene como objetivo describir comportamientos y capacidad de agencia de autocuidado de pacientes con insuficiencia cardiaca de una clínica cardiovascular de Medellín entre noviembre de 2007 y mayo de 2008. Es un estudio descriptivo con abordaje cuantitativo. La muestra fue de 206 adultos con insuficiencia cardiaca diagnosticados por sintomatología clínica, fracción de eyección menor o igual a 40%. Se usaron para la recolección de datos la Escala Capacidad de Agencia de Autocuidado desarrollada por Isemberg y Evers et ál. (1993, traducida por Gallego, que mide el nivel de agencia de autocuidado, y la Escala Comportamientos de Autocuidado validada en Colombia en 2007 por Arredondo, que mide la frecuencia de comportamientos de autocuidado de adultos con insuficiencia cardiaca en la solicitud de ayuda, adaptación a vivir con la enfermedad y el régimen terapéutico, modificación del autoconcepto y aceptación de sí mismo, vivir con efectos de la insuficiencia cardiaca y el tratamiento. Concluye que el mayor número de pacientes eran hombres; que factores básicos condicionantes como el apoyo de la familia, desempeño de un trabajo, afiliación al sistema de salud, nivel socioeconómico y acceso a un nivel educativo fueron importantes para los pacientes. La frecuencia de comportamientos de autocuidado fue media en los adultos en la mayoría de las dimensiones y el nivel de agencia fue alto y muy alto. Igualmente se concluyó que no hay una correlación entre agencia y comportamientos de autocuidado. Lo que plantea que los adultos tienen el conocimiento pero no han tomado la decisión de realizar acciones de autocuidado.

  20. The Designing Bus for Nuclear Safety Class Controller

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Dongil; Lee, Myeongkyun; Yun, Donghwa [PONUTech Co,. Ltd., Research Institute, Ulsan (Korea, Republic of); Ryoo, Kwangki [Hanbat National Univ., Daejeon (Korea, Republic of)

    2013-10-15

    EtherCAT (Ethernet for Control Automation Technology) is based on the IEEE 802.3 standard as one of the communication which is the I/O (Input/Output), sensors and communication function of PLC (Programmable Logic Controller) in industry and factory environment use is increasing. The Nuclear Safety Class Controller implemented by the EtherCAT applied bus can be shown the improving performance of data transmission in the controller.

  1. Regulatory control of nuclear safety in Finland. Annual report 1998

    Energy Technology Data Exchange (ETDEWEB)

    Tossavainen, K. [ed.

    1999-10-01

    The report describes regulatory control of the safe use of nuclear energy by the Radiation and Nuclear Safety Authority (STUK) in 1998. STUK is the Finnish nuclear safety authority. The submission of this report to the Ministry of Trade and Industry is stipulated in Section 121 of the Nuclear Energy Decree. It was verified by regulatory control that the operation of Finnish NPPs was in compliance with conditions set out in the operating licences of the plants and with regulations currently in force. In addition to supervising the normal operation of the plants, STUK oversaw projects carried out at the plant units, which related to the uprating of their power and the improvement of their safety. STUK issued to the Ministry of Trade and Industry a statement about applications for the renewal of the operating licences of Loviisa and Olkiluoto NPPs, which had been submitted by Imatran Voima Oy and Teollisuuden Voima Oy. Regulatory activities in the field of nuclear waste management were focused on the storage and final disposal of spent fuel as well as the treatment, storage and final disposal of reactor waste. STUK issued a statement to the Ministry of Trade and Industry about an environmental impact assessment programme pertaining to a spent fuel repository project, which had been submitted by Posiva Oy, as well as on Imatran Voima Oy's application concerning the operation of a repository for medium- and low-level reactor waste from Loviisa NPP. The use of nuclear materials was in compliance with the regulations currently in force and also the whereabouts of every batch of nuclear material were ensured by safeguards control. In international safeguards, important changes took place, which were reflected also in safeguards activities at national level. International co-operation continued based on financing both from STUK's budget and from additional sources. The focus of co-operation funded from outside sources was as follows: improvement of the safety of

  2. Mutual control of X-rays and nuclear transitions

    Energy Technology Data Exchange (ETDEWEB)

    Gunst, Jonas Friedrich

    2015-12-14

    In the course of this Thesis the mutual control between X-rays and nuclear transitions is investigated theoretically. In the first Part, we study the nuclear photoexcitation with the highly brilliant and coherent X-ray free-electron lasers (XFELs). Apart from amplifying the direct resonant interaction with nuclear transitions, the super-intense XFEL can produce new states of matter like cold, high-density plasmas where secondary nuclear excitation channels may come into play, e.g., nuclear excitation by electron capture (NEEC). Our results predict that in the case of {sup 57}Fe targets secondary NEEC can be safely neglected, whereas it is surprisingly the dominating contribution (in comparison to the direct photoexcitation) for the XFEL-induced {sup 93m}Mo isomer triggering. Based on these case studies, we elaborate a general set of criteria to identify the prevailing excitation channel for a certain nuclear isotope. These criteria may be most relevant for future nuclear resonance experiments at XFEL facilities. On the opposite frontier, the interplay between single X-ray photons and nuclear transitions offer potential storage and processing applications for information science in their most compact form. In the second Part of this Thesis, we show that nuclear forward scattering off {sup 57}Fe targets can be employed to process polarization-encoded single X-rays via timed magnetic field rotations. Apart from the realization of logical gates with X-rays, the polarization encoding is used to design an X-ray quantum eraser scheme where the interference between scattering paths can be switched off and on in a controlled manner. Such setups may advance time-energy complementarity tests to so far unexplored parameter regimes, e.g., to the domain of X-ray quanta.

  3. Use of hafnium in control bars of nuclear reactors; Uso de hafnio en barras de control de reactores nucleares

    Energy Technology Data Exchange (ETDEWEB)

    Ramirez S, J.R.; Alonso V, G. [ININ, 52045 Ocoyoacac, Estado de Mexico (Mexico)]. e-mail: jrrs@nuclear.inin-mx

    2003-07-01

    Recently the use of hafnium as neutron absorber material in nuclear reactors has been reason of investigation by virtue of that this material has nuclear properties as to the neutrons absorption and structural that can prolong the useful life of the control mechanisms of the nuclear reactors. In this work some of those more significant hafnium properties are presented like nuclear material. Also there are presented calculations carried out with the HELIOS code for fuel cells of uranium oxide and of uranium and plutonium mixed oxides under controlled conditions with conventional bars of boron carbide and also with similar bars to which are substituted the absorbent material by metallic hafnium, the results are presented in this work. (Author)

  4. Development of Nuclear Control and Management Information Treatment System

    Energy Technology Data Exchange (ETDEWEB)

    Yoo, J. G.; Lee, B. D.; So, D. S. [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2007-07-01

    To implement obligations under the Non-Proliferation Treaty (NPT) and the bilateral agreements more effectively, we proposed a computerized system named the Nuclear Control and Management Information Treatment System (NCAMITS) as a part of the Nuclear Transparency Enhancement Project at the Korea Atomic Energy Research Institute (KAERI). The database system is designed not only to undertake the facility-level accounting for and control of nuclear material at KAERI, but also to meet the requirements of the State (National) System of Accounting and Control (SSAC). Since the NCAMITS will provide services for the facility operators as well as the safeguard information managers at KAERI, the development of the system is supposed to accommodate the end-user's convenience and the manager's sophisticated specifications as well.

  5. Nuclear Instrumentation and Control Cyber Testbed Considerations – Lessons Learned

    Energy Technology Data Exchange (ETDEWEB)

    Jonathan Gray; Robert Anderson; Julio G. Rodriguez; Cheol-Kwon Lee

    2014-08-01

    Abstract: Identifying and understanding digital instrumentation and control (I&C) cyber vulnerabilities within nuclear power plants and other nuclear facilities, is critical if nation states desire to operate nuclear facilities safely, reliably, and securely. In order to demonstrate objective evidence that cyber vulnerabilities have been adequately identified and mitigated, a testbed representing a facility’s critical nuclear equipment must be replicated. Idaho National Laboratory (INL) has built and operated similar testbeds for common critical infrastructure I&C for over ten years. This experience developing, operating, and maintaining an I&C testbed in support of research identifying cyber vulnerabilities has led the Korean Atomic Energy Research Institute of the Republic of Korea to solicit the experiences of INL to help mitigate problems early in the design, development, operation, and maintenance of a similar testbed. The following information will discuss I&C testbed lessons learned and the impact of these experiences to KAERI.

  6. REFLECTIONS ON THE FUTURE OF NUCLEAR ARMS CONTROL IN 2011REFLECTIONS ON THE FUTURE OF NUCLEAR ARMS CONTROL IN 2011%REFLECTIONS ON THE FUTURE OF NUCLEAR ARMS CONTROL IN2011REFLECTIONS ON THE FUTURE OF NUCLEAR ARMS CONTROL IN2011

    Institute of Scientific and Technical Information of China (English)

    Paul Schulte

    2011-01-01

    @@ The first vision for removing the threat of nuclear weapons, within a year of their first use, was the far-reaching agenda of the Acheson Lilienthal Report on the International Control of Atomic Energy in 1946[1] proposing that all fissile material should be transferred to a new international agency (the Atomic Development Authority) which would release small amounts to individual nations for peaceful uses.This proposal, like many others, fell victim to the ideologically aggravated suspicions of the Cold War.But, over time, and even during periods of intense east-west suspicion, a substantial body of negotiated agreements has been achieved.Almost all necessarily involved the nuclear superpowers, who led the way in the expansion of nuclear weapons, and whose arsenals therefore needed to be limited as a precondition for achieving wider global nuclear stability.

  7. BENCHMARKING INTERNO EN UNA CENTRAL DE COMPRAS DE AGENCIAS DE VIAJES

    Directory of Open Access Journals (Sweden)

    Isabel Montero Muradas

    2010-01-01

    Full Text Available El sector turístico es uno de los más dinámicos de nuestra economía que necesita poner en marcha nuevas estrategias para mantener sus niveles de participación en el PIB. El objetivo de este trabajo es determinar, mediante un análisis conjunto probabilístico, utilizando el modelo de Rasch, la importancia relativa de los factores determinantes de la oferta turística de una alianza estratégica entre agencias de viajes: Travel Advisors Guild (TAG. En los resultados se destaca el posicionamiento de las agencias integradas en el TAG, así como los desajustes competitivos internos.

  8. Light signaling controls nuclear architecture reorganization during seedling establishment

    NARCIS (Netherlands)

    Bourbousse, C.; Mestiri, I.; Zabulon, G.; Bourge, M.; Formiggini, F.; Koini, M.A.; Brown, S.C.; Fransz, P.; Bowler, C.; Barneche, F.

    2015-01-01

    The spatial organization of chromatin can be subject to extensive remodeling in plant somatic cells in response to developmental and environmental signals. However, the mechanisms controlling these dynamic changes and their functional impact on nuclear activity are poorly understood. Here, we determ

  9. El papel de las agencias de seguros en la competencia entre compañías aseguradoras

    Directory of Open Access Journals (Sweden)

    Leonardo Medrano

    2008-01-01

    Full Text Available Este artículo estudia el mercado de seguros cuando las compañías aseguradoras (aseguradoras venden sus pólizas por medio de agencias de seguros (agencias o agentes. Analiza los efectos de las comisiones por ventas pagadas a las agencias en las primas de seguros y en el bienestar del consumidor. Se considera el comportamiento oportunista de las agencias al vender las pólizas emitidas por la aseguradora que le ofrece la comisión mas alta. Se consideran también diferentes estructuras de mercado: un duopolio de aseguradoras que compiten en comisiones (competencia entre aseguradoras, la colusión entre aseguradoras con las agencias manteniendose independientes (colusión horizontal o monopolio de aseguradoras y la colusión entre aseguradoras y agencias (integración vertical o agentes exclusivos. Mostramos que la competencia entre aseguradoras y la integración vertical generan primas más altas que la colusión horizontal. Además, mostramos que la comisión óptima desde del punto de vista del consumidor pueda ser mayor que la comisión generada por cualquiera de las tres estructuras de mercado antes señaladas

  10. Distribución del riesgo en el contrato de agencia comercial.

    Directory of Open Access Journals (Sweden)

    Jaime Alberto Mendieta

    2006-01-01

    Full Text Available El Nacimiento del contrato supone el recorrido de su definición jurídica, por ello resulta de suma importancia identificar la promoción y la distribución del riesgo como elementos distintivos en el contrato de agencia comercial, complemento de los ya tan discutidos elementos contenidos en el artículo 1317 del Código de Comercio.

  11. Distribución del riesgo en el contrato de agencia comercial.

    Directory of Open Access Journals (Sweden)

    Jaime Alberto Mendieta

    2006-06-01

    Full Text Available El Nacimiento del contrato supone el recorrido de su definición jurídica, por ello resulta de suma importancia identificar la promoción y la distribución del riesgo como elementos distintivos en el contrato de agencia comercial, complemento de los ya tan discutidos elementos contenidos en el artículo 1317 del Código de Comercio.

  12. Cranial Reconstruction following the Removal of an Infected Synthetic Dura Mater Substitute

    Directory of Open Access Journals (Sweden)

    Nobutaka Yoshioka, MD

    2014-04-01

    Conclusions: Staged cranial reconstruction after the removal of an infected synthetic dura mater substitute using an algorithmic approach is feasible and safe, produces satisfactory cosmetic results, and is not associated with any complications.

  13. Demonstration of Quantum Entanglement Control Using Nuclear Magnetic Resonance

    Institute of Scientific and Technical Information of China (English)

    XIE Jing-Yi; ZHANG Jing-Fu; DENG Zhi-Wei; LU Zhi-Heng

    2004-01-01

    @@ With the two forms of the quantum entanglement control, the quantum entanglement swapping and preservation are demonstrated in a three-qubit nuclear magnetic resonance quantum computer. The pseudopure state is prepared to represent the quantum entangled states through macroscopic signals. Entanglement swapping is directly realized by a swap operation. By controlling the interactions between the system and its environment,we can preserve an initial entangled state for a longer time. The experimental results are in agreement with the experiment.

  14. Next Generation Nuclear Plant Resilient Control System Functional Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Lynne M. Stevens

    2010-07-01

    Control Systems and their associated instrumentation must meet reliability, availability, maintainability, and resiliency criteria in order for high temperature gas-cooled reactors (HTGRs) to be economically competitive. Research, perhaps requiring several years, may be needed to develop control systems to support plant availability and resiliency. This report functionally analyzes the gaps between traditional and resilient control systems as applicable to HTGRs, which includes the Next Generation Nuclear Plant; defines resilient controls; assesses the current state of both traditional and resilient control systems; and documents the functional gaps existing between these two controls approaches as applicable to HTGRs. This report supports the development of an overall strategy for applying resilient controls to HTGRs by showing that control systems with adequate levels of resilience perform at higher levels, respond more quickly to disturbances, increase operational efficiency, and increase public protection.

  15. Mechanical and thermal properties of bacterial-cellulose-fibre-reinforced Mater-Bi® bionanocomposite

    Directory of Open Access Journals (Sweden)

    Hamonangan Nainggolan

    2013-05-01

    Full Text Available The effects of the addition of fibres of bacterial cellulose (FBC to commercial starch of Mater-Bi® have been investigated. FBC produced by cultivating Acetobacter xylinum for 21 days in glucose-based medium were purified by sodium hydroxide 2.5 wt % and sodium hypochlorite 2.5 wt % overnight, consecutively. To obtain water-free BC nanofibres, the pellicles were freeze dried at a pressure of 130 mbar at a cooling rate of 10 °C min−1. Both Mater-Bi and FBC were blended by using a mini twin-screw extruder at 160 °C for 10 min at a rotor speed of 50 rpm. Tensile tests were performed according to ASTM D638 to measure the Young’s modulus, tensile strength and elongation at break. A field emission scanning electron microscope was used to observe the morphology at an accelerating voltage of 10 kV. The crystallinity (Tc and melting temperature (Tm were measured by DSC. Results showed a significant improvement in mechanical and thermal properties in accordance with the addition of FBC into Mater-Bi. FBC is easily incorporated in Mater-Bi matrix and produces homogeneous Mater-Bi/FBC composite. The crystallinity of the Mater-Bi/FBC composites decrease in relation to the increase in the volume fraction of FBC.

  16. COMMERCIAL UTILITY PERSPECTIVES ON NUCLEAR POWER PLANT CONTROL ROOM MODERNIZATION

    Energy Technology Data Exchange (ETDEWEB)

    Jeffrey C. Joe; Ronald L. Boring; Julius J. Persensky

    2012-07-01

    Commercial nuclear power plants (NPPs) in the United States need to modernize their main control rooms (MCR). Many NPPs have done partial upgrades with some success and with some challenges. The Department of Energy’s (DOE) Light Water Reactor Sustainability (LWRS) Program, and in particular the Advanced Instrumentation and Controls (I&C) and Information Systems Technologies Research and Development (R&D) Pathway within LWRS, is designed to assist commercial nuclear power industry with their MCR modernization efforts. As part of this framework, a survey was issued to utility representatives of the LWRS Program Advanced Instrumentation, Information, and Control Systems/Technologies (II&C) Utility Working Group to obtain their views on a range of issues related to MCR modernization, including: drivers, barriers, and technology options, and the effects these aspects will have on concepts of operations, modernization strategies, and staffing. This paper summarizes the key survey results and discusses their implications.

  17. La agencia de medios en el nuevo escenario comunicativo / Media agency in the new communicative scenario

    Directory of Open Access Journals (Sweden)

    Araceli Castelló Martínez

    2014-12-01

    Full Text Available La industria comunicativa vive un periodo de cambios profundos a los que la agencia de medios, uno de los actores principales en el mercado publicitario, no ha permanecido ajena. La transmedialidad de los contenidos, los nuevos formatos publicitarios en los diferentes medios, el engagement que demanda el anunciante o el fomento de la experiencia del usuario, entre otros aspectos, han revolucionado la definición de las estrategias de medios. Los objetivos del presente artículo pasan por analizar el papel actual de la agencia de medios en el mercado publicitario y estudiar las características de las estrategias de medios en el presente contexto comunicativo así como su integración en las estrategias de comunicación. La metodología se basa en una revisión bibliográfica de publicaciones dedicadas a la planificación publicitaria y la agencia de medios en base a una serie de palabras clave y en un análisis de los servicios que ofrecen las agencias de medios en sus páginas web. Los resultados destacan el papel estratégico que ha adquirido la agencia de medios en el actual escenario comunicativo, por una parte, y la integración y la transmedialidad que caracterizan hoy en día a las estrategias de medios, por otra. Abstract Communication industry lives a period of profound changes that the media agency, one of the key players in the advertising market, has not remained apart from. Transmediality of contents, new advertising formats in the various media, the engagement that advertisers demand or the encouragement of the users experience, among others, have revolutionized the definition of media strategies.The goals of the present article focus on analyzing the current role of the media agency in the advertising market and studying the characteristics of media strategies in the present communicative context as well as their integration in communication strategies. The methodology is based on a literature review of publications devoted to

  18. Decontamination of control rod housing from Palisades Nuclear Power Station.

    Energy Technology Data Exchange (ETDEWEB)

    Kaminski, M.D.; Nunez, L.; Purohit, A.

    1999-05-03

    Argonne National Laboratory has developed a novel decontamination solvent for removing oxide scales formed on ferrous metals typical of nuclear reactor piping. The decontamination process is based on the properties of the diphosphonic acids (specifically 1-hydroxyethane-1,1-diphosphonic acid or HEDPA) coupled with strong reducing-agents (e.g., sodium formaldehyde sulfoxylate, SFS, and hydroxylamine nitrate, HAN). To study this solvent further, ANL has solicited actual stainless steel piping material that has been recently removed from an operating nuclear reactor. On March 3, 1999 ANL received segments of control rod housing from Consumers Energy's Palisades Nuclear Plant (Covert, MI) containing radioactive contamination from both neutron activation and surface scale deposits. Palisades Power plant is a PWR type nuclear generating plant. A total of eight segments were received. These segments were from control rod housing that was in service for about 6.5 years. Of the eight pieces that were received two were chosen for our experimentation--small pieces labeled Piece A and Piece B. The wetted surfaces (with the reactor's pressurized water coolant/moderator) of the pieces were covered with as a scale that is best characterized visually as a smooth, shiny, adherent, and black/brown in color type oxide covering. This tenacious oxide could not be scratched or removed except by aggressive mechanical means (e.g., filing, cutting).

  19. Enfermeiros e o Mercosul: regulamentação e controle do exercício profissional

    Directory of Open Access Journals (Sweden)

    Ana Luiza Stiebler Vieira

    1998-03-01

    Full Text Available Estudo comparado da regulamentação e controle do exercício profissional dos enfermeiros no Brasil, Argentina, Uruguai e Paraguai, delineando suas especificidades, diferenças e semelhanças, na perspectiva de implantação do Mercado Comum do Cone Sul, o qual pressupõe a livre circulação de trabalhadores nos mercados de trabalho dos países-membros do Tratado de Assunção.

  20. Methods of Verification, Accountability and Control of Special Nuclear Material

    Energy Technology Data Exchange (ETDEWEB)

    Stewart, J.E.

    1999-05-03

    This session demonstrates nondestructive assay (NDA) measurement, surveillance and analysis technology required to protect, control and account (MPC and A) for special nuclear materials (SNM) in sealed containers. These measurements, observations and analyses comprise state-of-the art, strengthened, SNM safeguards systems. Staff member specialists, actively involved in research, development, training and implementation worldwide, will present six NDA verification systems and two software tools for integration and analysis of facility MPC and A data.

  1. Robotic control architecture development for automated nuclear material handling systems

    Energy Technology Data Exchange (ETDEWEB)

    Merrill, R.D.; Hurd, R.; Couture, S.; Wilhelmsen, K.

    1995-02-01

    Lawrence Livermore National Laboratory (LLNL) is engaged in developing automated systems for handling materials for mixed waste treatment, nuclear pyrochemical processing, and weapon components disassembly. In support of these application areas there is an extensive robotic development program. This paper will describe the portion of this effort at LLNL devoted to control system architecture development, and review two applications currently being implemented which incorporate these technologies.

  2. Ergonomics in the licensing and evaluation of nuclear reactors control room; A ergonomia no licenciamento e na avaliacao de salas de controle de reatores nucleares

    Energy Technology Data Exchange (ETDEWEB)

    Santos, Isaac Jose Antonio Luquetti dos [Instituto de Engenharia Nuclear (IEN), Rio de Janeiro, RJ (Brazil); Vidal, Mario Cesar Rodriguez [Universidade Federal, Rio de Janeiro, RJ (Brazil). Coordenacao dos Programas de Pos-graduacao de Engenharia. Programa de Engenharia de Producao

    2002-07-01

    A nuclear control room is a complex system that controls a thermodynamic process used to produce electrical energy. The operators interact with the control room through interfaces that have significant implications to nuclear plant safety and influence the operator activity. The TMI (Three Mile Island) accident demonstrated that only the anthropometric aspects were not enough for an adequate nuclear control room design. The studies showed that the accident was aggravated because the designers had not considered adequately human factor aspects. After TMI accident, the designers introduce in the nuclear control room development only human factors standards and human factors guidelines. The ergonomics approaches was not considered. Our objective is introduce in nuclear control room design and nuclear control room evaluation, a methodology that. includes human factors standards, human factors guidelines and ergonomic approaches, the operator activity analysis. (author)

  3. Control of convergent yolk syncytial layer nuclear movement in zebrafish.

    Science.gov (United States)

    Carvalho, Lara; Stühmer, Jan; Bois, Justin S; Kalaidzidis, Yannis; Lecaudey, Virginie; Heisenberg, Carl-Philipp

    2009-04-01

    Nuclear movements play an essential role in metazoan development. Although the intracellular transport mechanisms underlying nuclear movements have been studied in detail, relatively little is known about signals from surrounding cells and tissues controlling these movements. Here, we show that, in gastrulating zebrafish embryos, convergence movements of nuclei within the yolk syncytial layer (YSL) are guided by mesoderm and endoderm progenitors migrating along the surface of the yolk towards the dorsal side of the developing gastrula. Progenitor cells direct the convergence movements of internal yolk syncytial nuclei (iYSN) by modulating cortical flow within the YSL in which the iYSN are entrained. The effect of mesoderm and endoderm progenitors on the convergence movement of iYSN depends on the expression of E-cadherin, indicating that adhesive contact between the cells and the YSL is required for the mesendoderm-modulated YSL cortical flow mediating nuclear convergence. In summary, our data reveal a crucial function for cortical flow in the coordination of syncytial nuclear movements with surrounding cells and tissues during zebrafish gastrulation.

  4. Development of Computer-Aided Learning Programs on Nuclear Nonproliferation and Control

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Hyun Chul [Korea Institute of Nuclear Nonproliferation and Control, Daejeon (Korea, Republic of)

    2011-10-15

    The fulfillment of international norms for nuclear nonproliferation is indispensable to the promotion of nuclear energy. The education and training for personnel and mangers related to the nuclear material are one of crucial factors to avoid unintended non-compliance to international norms. Korea Institute of Nuclear Nonproliferation and Control (KINAC) has been providing education and training on nuclear control as its legal duty. One of the legally mandatory educations is 'nuclear control education' performed since 2006 for the observation of the international norms on nuclear nonproliferation and the spread of the nuclear control culture. The other is 'physical protection education' performed since 2010 for maintaining the national physical protection regime effectively and the spread of the nuclear security culture. The 2010 Nuclear Security Summit was held in Washington, DC to enhance international cooperation to prevent nuclear terrorism. During the Summit, the South Korea was chosen to host the second Nuclear Summit in 2012. South Korean President announced that South Korea would share its expertise and support the Summit's mission by setting up an international education and training center on nuclear security in 2014. KINAC is making a full effort to set up the center successfully. An important function of the center is education and training in the subjects of nuclear nonproliferation, nuclear safeguards, nuclear security, and nuclear export/import control. With increasing importance of education and training education on nuclear nonproliferation and control, KINAC has been developing computer-aided learning programs on nuclear nonproliferation and control to overcome the weaknesses in classroom educations. This paper shows two learning programs. One is an e-learning system on the nuclear nonproliferation and control and the other is a virtual reality program for training nuclear material accountancy inspection of light water

  5. Basic Model of a Control Assembly Drop in Nuclear Reactors

    Directory of Open Access Journals (Sweden)

    Radek BULÍN

    2013-06-01

    Full Text Available This paper is focused on the modelling and dynamic analysis of a nonlinear system representing a control assembly of the VVER 440/V213 nuclear reactor. A simple rigid body model intended for basic dynamic analyses is introduced. It contains the influences of the pressurized water and mainly the eects of possible control assembly contacts with guiding tubes inside the reactor. Another approach based on a complex multibody model is further described and the suitability of both modelling approaches is discussed.

  6. Nuclear PTEN controls DNA repair and sensitivity to genotoxic stress

    Science.gov (United States)

    Bassi, C; Ho, J; Srikumar, T; Dowling, RJO; Gorrini, C; Miller, SJ; Mak, TW; Neel, BG; Raught, B; Stambolic, V

    2016-01-01

    Loss of function of the Phosphatase and tensin homologue deleted on chromosome 10 (PTEN) tumor suppressor gene is associated with many human cancers. In the cytoplasm, PTEN antagonizes the Phosphatidylinositol 3′ kinase (PI3K) signaling pathway. PTEN also accumulates in the nucleus, where its function remains poorly understood. We demonstrate that SUMOylation (SUMO) of PTEN controls its nuclear localization. In cells exposed to genotoxic stress, SUMO-PTEN was rapidly excluded from the nucleus dependent on the protein kinase Ataxia telangiectasia mutated (ATM). Cells lacking nuclear PTEN were hypersensitive to DNA damage, while PTEN-deficient cells were susceptible to killing by a combination of genotoxic stress and a small molecule PI3K inhibitor both in vitro and in vivo. Our findings may have implications for individualized therapy for patients with PTEN-deficient tumors. PMID:23888040

  7. Heterogeneous Nuclear Reactor Models for Optimal Xenon Control.

    Science.gov (United States)

    Gondal, Ishtiaq Ahmad

    Nuclear reactors are generally modeled as homogeneous mixtures of fuel, control, and other materials while in reality they are heterogeneous-homogeneous configurations comprised of fuel and control rods along with other materials. Similarly, for space-time studies of a nuclear reactor, homogeneous, usually one-group diffusion theory, models are used, and the system equations are solved by either nodal or modal expansion approximations. Study of xenon-induced problems has also been carried out using similar models and with the help of dynamic programming or classical calculus of variations or the minimum principle. In this study a thermal nuclear reactor is modeled as a two-dimensional lattice of fuel and control rods placed in an infinite-moderator in plane geometry. The two-group diffusion theory approximation is used for neutron transport. Space -time neutron balance equations are written for two groups and reduced to one space-time algebraic equation by using the two-dimensional Fourier transform. This equation is written at all fuel and control rod locations. Iodine -xenon and promethium-samarium dynamic equations are also written at fuel rod locations only. These equations are then linearized about an equilibrium point which is determined from the steady-state form of the original nonlinear system equations. After studying poisonless criticality, with and without control, and the stability of the open-loop system and after checking its controllability, a performance criterion is defined for the xenon-induced spatial flux oscillation problem in the form of a functional to be minimized. Linear -quadratic optimal control theory is then applied to solve the problem. To perform a variety of different additional useful studies, this formulation has potential for various extensions and variations; for example, different geometry of the problem, with possible extension to three dimensions, heterogeneous -homogeneous formulation to include, for example, homogeneously

  8. Nonlinear H-infinity control of nuclear steam generators

    Science.gov (United States)

    Ramalho, Fernando Pinto

    Motivated by the fact that problems related to the control of steam generators are responsible for a significant amount of downtime in nuclear power plants, this thesis investigates the applicability of linear and nonlinear Hinfinity theory to the control of nuclear steam generators. A nonlinear model based on mass, energy, and momentum balances was developed for a U-tube steam generator, with the water level and steam quality at the exit of the riser considered as state variables. In this model the steam flow to the turbines and the heat flow from the primary to the secondary side are represented as disturbances affecting the system, while the feedwater flow is used to compensate for changes in the water level. The performance specifications for the feedback loop are encoded using weight functions incorporated into an augmented plant, and the control problem is formulated to minimize the effects of disturbances on the controlled variables. The solution of the optimization problem is reduced to the solution of a set of differential equations, which, in the linear case, is equivalent to the solution of Riccati equations. The linear Hinfinity controller and filter were obtained for the U-tube steam generator with and without weight functions, and simulations for a 50 s ramp transient resulting in 50% decrease in the heat and steam flows were performed over 300 s. The use of weights provided less variation in the water level, and an excellent noise rejection capability was observed. For the nonlinear Hinfinity formulation a finite-difference method was used to solve the state and costate equations numerically for optimal feedwater flow minimizing water level variations. The combined solution of the state equation in the forward direction and the costate equations in the backward direction converged in 10 iteractions. The nonlinear controller results in less variation in the water level than the corresponding linear Hinfinity controller, demonstrating the feasibility

  9. PLAN DE NEGOCIO PARA UNA AGENCIA DEDICADA A MARKETING DIGITAL, ESPECIALMENTE PARA EL MERCADO CHINO

    OpenAIRE

    HUANG, JIARUI

    2014-01-01

    El presente plan de negocio analiza la viabilidad del proyecto empresarial de una Agencia de Marketing online, especialmente relacionado con el mercado Chino. Se ofrecerá a los clientes servicios marketing para introducir y/o establecer al mercado chino, tanto para mercado chino en China o en España. El proyecto surge de la tendencia del sector y la experiencia personal. El sector de marketing es un campo en permanente crecimiento y renovación, donde el perfil de clientes incorpora progres...

  10. El impacto del reglamento «Roma I» en el contrato internacional de agencia

    OpenAIRE

    Aguilar Grieder, Hilda

    2011-01-01

    El Reglamento «Roma I» sobre la ley aplicable a las obligaciones contractuales ha introducido modifi caciones sustanciales relevantes con respecto a su antecesor: el Convenio de Roma. Algunas de las novedades del Reglamento «Roma I» afectan al régimen general de determinación de la lex contractus, dentro del cual queda encuadrado uno de los contratos más habituales en la práctica comercial internacional de nuestros días: el contrato internacional de agencia comercial. El presente ...

  11. El contrato de agencia comercial. Análisis dentro del contexto del derecho romano

    OpenAIRE

    María Elisa Camacho López

    2009-01-01

    Sumario: Premisa. Principios derivados del sistema jurídico romano-germánico aplicables al contrato de agencia comercial. i. Algunas figuras de la actividad mercantil en el derecho romano. ii. Cláusulas de no competencia. A. Posibles fuentes de la obligación de no competencia en el derecho romano. 1. Obsequium. 2. Operae iuratae. 3. Operae stipulatae. 4. Stipulatio. 5. Contratos innominados. 6. Lex mancipii. B. Licitud o ilicitud de la obligación de no competencia en el derecho romano. C. Con...

  12. Redes sociales y modelos de agencias ciudadanas de comunicación

    OpenAIRE

    Viana, César

    2011-01-01

    El uso voluntario y espontáneo de las redes sociales también resulta en procesos históricos, etnográficos, antropológicos y sociológicos. Esta investigación se basa en un estudio de mercado que demuestra los usos, hábitos y tendencias de las redes sociales en España, Brasil y México. Los datos analizados indican el potencial para que se establezca una agencia ciudadana de comunicación entre los usuarios de sistemas informáticos que posibilitan la convivencia en redes en nivel mundial, desde q...

  13. CAPACIDAD DE AGENCIA DE AUTOCUIDADO EN LAS PERSONAS ADULTAS QUE PADECEN ARTRITIS REUMATOIDE

    OpenAIRE

    2012-01-01

    El objetivo de la investigación consistió en analizar la capacidad de agencia de autocuidado que poseen laspersonas con diagnóstico de artritis reumatoide, quienes habitan en los cantones de Palmares y San Ramón. Se desarrolló una metodología de investigación cuantitativa de tipo descriptiva transversal. En cuanto a la población participante del estudio, estuvo conformada por 13 personas diagnosticadas con artritis reumatoide; respecto de los instrumentos utilizados para recolectar informació...

  14. An Approach to Autonomous Control for Space Nuclear Power Systems

    Energy Technology Data Exchange (ETDEWEB)

    Wood, Richard Thomas [ORNL; Upadhyaya, Belle R. [University of Tennessee, Knoxville (UTK)

    2011-01-01

    Under Project Prometheus, the National Aeronautics and Space Administration (NASA) investigated deep space missions that would utilize space nuclear power systems (SNPSs) to provide energy for propulsion and spacecraft power. The initial study involved the Jupiter Icy Moons Orbiter (JIMO), which was proposed to conduct in-depth studies of three Jovian moons. Current radioisotope thermoelectric generator (RTG) and solar power systems cannot meet expected mission power demands, which include propulsion, scientific instrument packages, and communications. Historically, RTGs have provided long-lived, highly reliable, low-power-level systems. Solar power systems can provide much greater levels of power, but power density levels decrease dramatically at {approx} 1.5 astronomical units (AU) and beyond. Alternatively, an SNPS can supply high-sustained power for space applications that is both reliable and mass efficient. Terrestrial nuclear reactors employ varying degrees of human control and decision-making for operations and benefit from periodic human interaction for maintenance. In contrast, the control system of an SNPS must be able to provide continuous operatio for the mission duration with limited immediate human interaction and no opportunity for hardware maintenance or sensor calibration. In effect, the SNPS control system must be able to independently operate the power plant while maintaining power production even when subject to off-normal events and component failure. This capability is critical because it will not be possible to rely upon continuous, immediate human interaction for control due to communications delays and periods of planetary occlusion. In addition, uncertainties, rare events, and component degradation combine with the aforementioned inaccessibility and unattended operation to pose unique challenges that an SNPS control system must accommodate. Autonomous control is needed to address these challenges and optimize the reactor control design.

  15. Fuzzy control applied to nuclear power plant pressurizer system

    Energy Technology Data Exchange (ETDEWEB)

    Oliveira, Mauro V.; Almeida, Jose C.S., E-mail: mvitor@ien.gov.b, E-mail: jcsa@ien.gov.b [Instituto de Engenharia Nuclear (IEN/CNEN-RJ), Rio de Janeiro, RJ (Brazil)

    2011-07-01

    In a pressurized water reactor (PWR) nuclear power plants (NPPs) the pressure control in the primary loop is very important for keeping the reactor in a safety condition and improve the generation process efficiency. The main component responsible for this task is the pressurizer. The pressurizer pressure control system (PPCS) utilizes heaters and spray valves to maintain the pressure within an operating band during steady state conditions, and limits the pressure changes, during transient conditions. Relief and safety valves provide overpressure protection for the reactor coolant system (RCS) to ensure system integrity. Various protective reactor trips are generated if the system parameters exceed safe bounds. Historically, a proportional-integral derivative (PID) controller is used in PWRs to keep the pressure in the set point, during those operation conditions. The purpose of this study has two main goals: first is to develop a pressurizer model based on artificial neural networks (ANNs); second is to develop a fuzzy controller for the PWR pressurizer pressure, and compare its performance with the P controller. Data from a simulator PWR plant was used to test the ANN and the controllers as well. The reference simulator is a Westinghouse 3-loop PWR plant with a total thermal output of 2785 MWth. The simulation results show that the pressurizer ANN model response are in reasonable agreement with the simulated power plant, and the fuzzy controller built in this study has better performance compared to the P controller. (author)

  16. The evolution of legal approaches to controlling nuclear and radiological weapons and combating the threat of nuclear terrorism

    NARCIS (Netherlands)

    J. Herbach

    2015-01-01

    This chapter traces the evolution of international law related to the weaponization of nuclear and other radioactive materials, focusing in particular on the law pertaining to preventing acts of nuclear terrorism. International efforts to control atomic energy have evolved substantially since the on

  17. Liquidación de tributos aduaneros y responsabilidad social de los importadores y Agencias de Aduanas en Colombia

    OpenAIRE

    2013-01-01

    La investigación “Liquidación de Tributos Aduaneros y Responsabilidad Social de los Importadores y Agencias de Aduanas en Colombia”, presenta un análisis con respecto al proceso de importación de mercancías extranjeras especialmente en la liquidación y pago de tributos aduaneros como práctica de responsabilidad social empresarial – RES de las agencias de aduanas en Colombia, por ser el tributo un instrumento para proporcionar los dineros que financian las necesidades del Estado como congl...

  18. El enfoque de las capacidades, la agencia cognitiva y los recursos morales

    Directory of Open Access Journals (Sweden)

    Agustín Reyes Morela

    2012-02-01

    Full Text Available El enfoque de Sen se presenta como una alternativa en el terreno de la justicia distributiva. Su noción central es la de capacidad de agencia, es decir, la libertad efectiva para alcanzar aquello que se tienen razones para valorar. A su vez, la idea de agencia cognitiva refiere a la capacidad de revisar o reforzar estas razones. Bajo la autocomprensión de las sociedades modernas, la única forma válida de desarrollarla es a través de la deliberación pública. Del intercambio surgen los recursos morales (entre ellos las razones morales que permiten modificar la concepción del bien y fortalecer sentido de justicia de los sujetos.The Sen’s approach is presented as an alternative in the field of distributive justice. Its main concept is the capability of agency, namely the effective freedom to achieve whatever you have reason to value. In turn, the idea of cognitive agency refers to the capability to review and strengthen these reasons. Under the self-understanding of modern societies, the only valid way to develop them is through public deliberation. Through the exchange emerge the moral resources that allow to modify the conception of the good and strengthen the sense of justice of the people.

  19. Radioactive Iodine and Krypton Control for Nuclear Fuel Reprocessing Facilities

    Directory of Open Access Journals (Sweden)

    Nick R. Soelberg

    2013-01-01

    Full Text Available The removal of volatile radionuclides generated during used nuclear fuel reprocessing in the US is almost certain to be necessary for the licensing of a reprocessing facility in the US. Various control technologies have been developed, tested, or used over the past 50 years for control of volatile radionuclide emissions from used fuel reprocessing plants. The US DOE has sponsored, since 2009, an Off-gas Sigma Team to perform research and development focused on the most pressing volatile radionuclide control and immobilization problems. In this paper, we focus on the control requirements and methodologies for 85Kr and 129I. Numerous candidate technologies have been studied and developed at laboratory and pilot-plant scales in an effort to meet the need for high iodine control efficiency and to advance alternatives to cryogenic separations for krypton control. Several of these show promising results. Iodine decontamination factors as high as 105, iodine loading capacities, and other adsorption parameters including adsorption rates have been demonstrated under some conditions for both silver zeolite (AgZ and Ag-functionalized aerogel. Sorbents, including an engineered form of AgZ and selected metal organic framework materials (MOFs, have been successfully demonstrated to capture Kr and Xe without the need for separations at cryogenic temperatures.

  20. The ANEEL and the PL 3.337/2004; analysis of the management, organization and social control of the regulator agencies under the legal optics; A ANEEL e o PL 3.337/2004: uma analise da gestao, organizacao e controle social das agencias reguladoras sob o prisma juridico

    Energy Technology Data Exchange (ETDEWEB)

    Costa, Hirdan Katarina de Medeiros; Bermann, Celio [Universidade de Sao Paulo (USP), SP (Brazil). Inst. de Eletrotecnica e Energia. Programa Interunidades de Pos-Graduacao em Energia]. E-mails: hirdanmedeiros@iee.usp.br; cbermann@iee.usp.br

    2006-07-01

    Since 1990 movement of opening economic sectors and public services long ago explored only the State in Brazil, what it parallel caused the institution of agencies with the target to oversee and to regulate definitive sector affection to the utility public. Ahead of this context, the agency process was attended to it, with looks it to monitor, to regulate and to oversee the activities of steady the incoming actors and already in these markets by means of specific and various laws. Thus, justifying the importance of the existence of a General Law of the Regulating Agencies, the Legislative Bill meets in the National Congress no. 3.337/04. Therefore, the present work, by means of bibliographical research and analysis the Bill in question, it intended to approach the points most controversial raised by studious of the Brazilian right in relation to the impact of the these changes proposals in the structure of the National Agency of Electric Energy. In this direction, the main focus was the contract of management, the interaction between the agencies and the institutions of free market defense, the agencies of control and the public hearings and consultations. (author)

  1. Interaction of ionizing radiation with mater; Oddzialywanie promieniowania jonizujacego z materia

    Energy Technology Data Exchange (ETDEWEB)

    Pogocki, D. [Institute of Nuclear Chemistry and Technology, Warsaw (Poland)

    1997-10-01

    The early radiation effects (e.g. excitation, ionization) have been described and compared for different kind of radiation interacting with mater. The mechanism of energy deposition in connection with radiation dose and their spatial distribution has been shown.The commonly used definitions and units in radiation dosimetry have been also reviewed. 4 refs, 4 figs.

  2. To the Editor: comment on Eremets and Troyan, Nature Mater. 10, 927-931 (2011)

    OpenAIRE

    Goncharov, Alexander F.; Struzhkin, Viktor V.

    2012-01-01

    Eremets and Troyan (Nature Mater. 10, 927-931 (2011)) claim that they produced the conducting liquid hydrogen state at 270 GPa and 295 K. Their evidence consists of disappearance of Raman signals, visual observations, and measurements of electrical conductivity in diamond anvil cells (DAC). However, there is no proof that the reported observations are due to transformations in hydrogen.

  3. Evidence for CGRP re-uptake in rat dura mater encephali

    DEFF Research Database (Denmark)

    Gupta, Saurabh; Amrutkar, Dipak Vasantrao; Mataji, Aydin;

    2010-01-01

    Calcitonin gene-related peptide (CGRP) is widely distributed in the trigeminovascular system and released from sensory fibres of the cranial dura mater upon noxious stimulation. Such release may be a mechanism underlying migraine headache. Based on data from guinea pig basilar artery preparations...

  4. Nuclear Command, Control, and Communications: Update on DOD’s Modernization

    Science.gov (United States)

    2015-06-15

    Page 1 GAO-15-584R NC3 Modernization Review 441 G St. N.W. Washington, DC 20548 June 15, 2015 Congressional Committees Nuclear Command...Control, and Communications: Update on DOD’s Modernization Nuclear command, control, and communications (NC3) is a large and complex system... architecture consists of components that support day-to-day nuclear and conventional operations prior to a nuclear event as well as those that provide

  5. 10 CFR 74.31 - Nuclear material control and accounting for special nuclear material of low strategic significance.

    Science.gov (United States)

    2010-01-01

    ... and maintain a measurement system which assures that all quantities in the material accounting records...) In each inventory period, control total material control and accounting measurement uncertainty so... 10 Energy 2 2010-01-01 2010-01-01 false Nuclear material control and accounting for...

  6. Voluntary Code of Conduct for Nuclear Export Control by Private Sector

    Energy Technology Data Exchange (ETDEWEB)

    Jo, Seong Youn; Shin, Dong Hoon [Korea Institute of Nuclear Non-Prolferation and Control Daejeon (Korea, Republic of)

    2011-10-15

    The nuclear renaissance offered a good opportunity to overcome energy crisis that we are bound to confront in the near future. At the opposite end, however, our world might be exposed to a new threat which could be resulted from the boost of nuclear power. The expansion of nuclear power plants worldwide inevitably makes the countries involve more transaction in nuclear items, which could lead to increase in nuclear proliferation risk. The international efforts to prevent proliferation attempts have been mainly being focused on limitation of nuclear sensitive technology and nuclear material. Considering the governments of major nuclear suppliers' key roles in the stage, it should be notable that a new initiative by private nuclear companies has been raised for the purpose of strengthening nuclear export control

  7. Information Foraging in Nuclear Power Plant Control Rooms

    Energy Technology Data Exchange (ETDEWEB)

    R.L. Boring

    2011-09-01

    nformation foraging theory articulates the role of the human as an 'informavore' that seeks information and follows optimal foraging strategies (i.e., the 'information scent') to find meaningful information. This paper briefly reviews the findings from information foraging theory outside the nuclear domain and then discusses the types of information foraging strategies operators employ for normal and off-normal operations in the control room. For example, operators may employ a predatory 'wolf' strategy of hunting for information in the face of a plant upset. However, during routine operations, the operators may employ a trapping 'spider' strategy of waiting for relevant indicators to appear. This delineation corresponds to information pull and push strategies, respectively. No studies have been conducted to determine explicitly the characteristics of a control room interface that is optimized for both push and pull information foraging strategies, nor has there been empirical work to validate operator performance when transitioning between push and pull strategies. This paper explores examples of control room operators as wolves vs. spiders and con- cludes by proposing a set of research questions to investigate information foraging in control room settings.

  8. A versatile computer-controlled pulsed nuclear quadrupole resonance spectrometer

    Science.gov (United States)

    Fisher, Gregory; MacNamara, Ernesto; Santini, Robert E.; Raftery, Daniel

    1999-12-01

    A new, pulsed nuclear quadrupole resonance (NQR) spectrometer capable of performing a variety of pulsed and swept experiments is described. The spectrometer features phase locked, superheterodyne detection using a commercial spectrum analyzer and a fully automatic, computer-controlled tuning and matching network. The tuning and matching network employs stepper motors which turn high power air gap capacitors in a "moving grid" optimization strategy to minimize the reflected power from a directional coupler. In the duplexer circuit, digitally controlled relays are used to switch different lengths of coax cable appropriate for the different radio frequencies. A home-built pulse programmer card controls the timing of radio frequency pulses sent to the probe, while data acquisition and control software is written in Microsoft Quick Basic. Spin-echo acquisition experiments are typically used to acquire the data, although a variety of pulse sequences can be employed. Scan times range from one to several hours depending upon the step resolution and the spectral range required for each experiment. Pure NQR spectra of NaNO2 and 3-aminopyridine are discussed.

  9. HFE safety reviews of advanced nuclear power plant control rooms

    Science.gov (United States)

    Ohara, John

    1994-01-01

    Advanced control rooms (ACR's) will utilize human-system interface (HSI) technologies that may have significant implications for plant safety in that they will affect the operator's overall role and means of interacting with the system. The Nuclear Regulatory Commission (NRC) reviews the human factors engineering (HFE) aspects of HSI's to ensure that they are designed to good HFE principles and support performance and reliability in order to protect public health and safety. However, the only available NRC guidance was developed more than ten years ago, and does not adequately address the human performance issues and technology changes associated with ACR's. Accordingly, a new approach to ACR safety reviews was developed based upon the concept of 'convergent validity'. This approach to ACR safety reviews is described.

  10. Flammability Control In A Nuclear Waste Vitrification System

    Energy Technology Data Exchange (ETDEWEB)

    Zamecnik, John R.; Choi, Alexander S.; Johnson, Fabienne C.; Miller, Donald H.; Lambert, Daniel P.; Stone, Michael E.; Daniel, William E. Jr.

    2013-07-25

    The Defense Waste Processing Facility at the Savannah River Site processes high-level radioactive waste from the processing of nuclear materials that contains dissolved and precipitated metals and radionuclides. Vitrification of this waste into borosilicate glass for ultimate disposal at a geologic repository involves chemically modifying the waste to make it compatible with the glass melter system. Pretreatment steps include removal of excess aluminum by dissolution and washing, and processing with formic and nitric acids to: 1) adjust the reduction-oxidation (redox) potential in the glass melter to reduce radionuclide volatility and improve melt rate; 2) adjust feed rheology; and 3) reduce by steam stripping the amount of mercury that must be processed in the melter. Elimination of formic acid in pretreatment has been studied to eliminate the production of hydrogen in the pretreatment systems, which requires nuclear grade monitoring equipment. An alternative reductant, glycolic acid, has been studied as a substitute for formic acid. However, in the melter, the potential for greater formation of flammable gases exists with glycolic acid. Melter flammability is difficult to control because flammable mixtures can be formed during surges in offgases that both increase the amount of flammable species and decrease the temperature in the vapor space of the melter. A flammable surge can exceed the 60% of the LFL with no way to mitigate it. Therefore, careful control of the melter feed composition based on scaled melter surge testing is required. The results of engineering scale melter tests with the formic-nitric flowsheet and the use of these data in the melter flammability model are presented.

  11. Intelligent control and automation technology for nuclear application

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Jae Hee; Eom, Heung Sub; Kim, Ko Ryu; Lee, Jae Cheol; Choi, You Rak; Lee, Soo Cheol [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)

    1996-06-01

    Using recent technologies on a mobile robot and computer science, we developed an automatic inspection system for weld lines of the reactor pressure vessel. The ultrasonic inspection of the reactor pressure vessel is currently performed by commercialized robot manipulators. Since, however, the conventional fixed type robot manipulator is very huge, heavy and expensive, it needs long inspection time and is hard to handle and maintain. In order to resolve these problems, we developed a new inspection automation system using a small mobile robot crawling on the vertical wall. According to the conceptual design studied in the first year, we developed the inspection automation system including an underwater inspection robot, a laser position control subsystem and a main control subsystem. And we carried out underwater experiments on the reactor vessel mockup. After finishing this project successfully, we have a plan to commercialize our inspection system. Using this system, we can expect much reduction of the inspection time, performance enhancement, automatic management of inspection history, etc. In the economic point of view, we can also expect import substitution more than 5 million dollars. The established essential technologies for intelligent control and automation are expected to be synthetically applied to the automation of similar systems in nuclear power plants. 4 tabs., 37 figs., 6 refs. (Author).

  12. El contrato de agencia comercial. Análisis dentro del contexto del derecho romano

    Directory of Open Access Journals (Sweden)

    María Elisa Camacho López

    2009-06-01

    Full Text Available Sumario: Premisa. Principios derivados del sistema jurídico romano-germánico aplicables al contrato de agencia comercial. i. Algunas figuras de la actividad mercantil en el derecho romano. ii. Cláusulas de no competencia. A. Posibles fuentes de la obligación de no competencia en el derecho romano. 1. Obsequium. 2. Operae iuratae. 3. Operae stipulatae. 4. Stipulatio. 5. Contratos innominados. 6. Lex mancipii. B. Licitud o ilicitud de la obligación de no competencia en el derecho romano. C. Condena por el incumplimiento de la obligación de no competir. iii. Consecuencias de la terminación del contrato. A. Revocación del mandato por parte del mandante. B. Renuncia del mandato por parte del mandatario. iv. Conclusiones

  13. Agencias de empleo y desarrollo local: ¿una actividad del Tercer Sector?

    Directory of Open Access Journals (Sweden)

    Ricardo Calvo Palomares

    2010-01-01

    Full Text Available En la actualidad, el desarrollo económico y social de un territorio necesita de los esfuerzos mancomunados de todos y cada uno de los agentes presentes en el medio. Es por ello que el presente artículo pretende reflexionar sobre la vinculación directa existente entre dos de ellos, por un lado las Agencias de Desarrollo Local (ADL como máximo exponente del modelo de desarrollo local y por otro las organizaciones pertenecientes al Tercer Sector, como entidades clave en el sostenimiento y desarrollo social de la comunidad. Para ello partiendo de las características propias del modelo actual de desarrollo local implantado, propondremos dos decálogos de conclusiones, que analicen tanto las similitudes como las divergencias existentes entre estos dos modelos.

  14. El espionaje y agencias de seguridad: los Estados Unidos y la Federación Rusa

    Directory of Open Access Journals (Sweden)

    Daniela Alejandra Alba Useche

    2014-01-01

    Full Text Available La evolución del espionaje y la tecnología desde la Guerra Fría entre los Estados Unidos y la Federación Rusa se ha desarrollado a través de las Agencias de Seguridad, pero desde los ataques del 11-S, hubo un giro en los métodos de atacar el terrorismo; este tema se convirtió en la prioridad para Estados Unidos y para el resto del mundo. Por esta razón, se están desarrollando vertiginosamente programas de vigilancia, recopilación y análisis de información, sirviéndose del ciberespacio y del ciberespionaje, donde ahora todos somos observados y la privacidad ha sido reemplazada por la vigilancia ‘en aras’ de la seguridad.

  15. Controlling the power output of a nuclear reactor with fuzzy logic

    NARCIS (Netherlands)

    Ruan, D.; Wal, A.J. van der

    1998-01-01

    The application of fuzzy logic control (FLC) in the domain of nuclear industry presents a tremendous challenge. The main reason for this is the public awareness of the risks of nuclear reactors and the very strict safety regulations in force for nuclear power plants. The very same regulations preven

  16. Controlling the Power Output of a Nuclear Reactor with Fuzzy Logic

    NARCIS (Netherlands)

    Ruan, D.; Wal, A.J. van der

    1997-01-01

    The application of fuzzy logic control (FLC) in the domain of nuclear industry presents a tremendous challenge. The main reason for this is the public awareness of the risks of nuclear reactors and the very strict safety regulations in force for nuclear power plants. The very same regulations preven

  17. Understanding Nuclear Weapons and Arms Control: A Guide to the Issues. New Edition.

    Science.gov (United States)

    Mayers, Teena

    Intended for secondary and college level students and teachers, this guide discusses the nuclear arms control issue. There are four sections. Section I discusses U.S. nuclear strategy from 1945 to the present, strategic nuclear weapons competition between the United States and the Union of Soviet Socialist Republics (U.S.S.R.), U.S.…

  18. Evolution in nuclear strategy in US and Russia and its implications in arms control

    Energy Technology Data Exchange (ETDEWEB)

    Sokov, N

    2003-07-01

    Today, there is a growing tendency in war-fighting scenarios to include limited use of nuclear weapons. New developments in nuclear policy could be attributed to changes in the international situation like the multiplication of low level conflicts and the threat of terrorism. This paper analyzes the evolution of the Russian nuclear doctrine, the transformation of the US nuclear policy and their consequences on arms control. (J.S.)

  19. Experiences in the computerized control rooms design for Nuclear Power Plants; Experiencias en el diseno de salas de control computarizadas para centrales nucleares

    Energy Technology Data Exchange (ETDEWEB)

    Moyano de la Heras, N.; Fernandez Illobre, L.; Valdivia Martin, C.

    2010-07-01

    This paper presents Tecnatom experiences obtained during the control rooms design for the Fuming and Fangjiasham Nuclear Power Plants (CPR type). These are two different locations where two pressurized water reactors, with three loops each one, will be installed.

  20. Chm7 and Heh1 collaborate to link nuclear pore complex quality control with nuclear envelope sealing.

    Science.gov (United States)

    Webster, Brant M; Thaller, David J; Jäger, Jens; Ochmann, Sarah E; Borah, Sapan; Lusk, C Patrick

    2016-11-15

    The integrity of the nuclear envelope barrier relies on membrane remodeling by the ESCRTs, which seal nuclear envelope holes and contribute to the quality control of nuclear pore complexes (NPCs); whether these processes are mechanistically related remains poorly defined. Here, we show that the ESCRT-II/III chimera, Chm7, is recruited to a nuclear envelope subdomain that expands upon inhibition of NPC assembly and is required for the formation of the storage of improperly assembled NPCs (SINC) compartment. Recruitment to sites of NPC assembly is mediated by its ESCRT-II domain and the LAP2-emerin-MAN1 (LEM) family of integral inner nuclear membrane proteins, Heh1 and Heh2. We establish direct binding between Heh2 and the "open" forms of both Chm7 and the ESCRT-III, Snf7, and between Chm7 and Snf7. Interestingly, Chm7 is required for the viability of yeast strains where double membrane seals have been observed over defective NPCs; deletion of CHM7 in these strains leads to a loss of nuclear compartmentalization suggesting that the sealing of defective NPCs and nuclear envelope ruptures could proceed through similar mechanisms.

  1. Claudia Quinta (Pro Caelio 34 and an altar to Magna Mater

    Directory of Open Access Journals (Sweden)

    Eleanor Winsor Leach

    2010-11-01

    Full Text Available Among the items of sculpture from the Capitoline collection now housed in the Museum of the Power Station Montemartini is a marble relief altar of the Claudian Period (E. Simon's dating dedicated to the mater deorum and the navis salvia and depicting the arrival of the goddess Cybele at Rome by ship. The dedicator is one Claudia Syntyche and the sculpture alludes to the legends attached to a much honored woman of the Claudian family whom Cicero, in his oration pro Caelio brought on stage in a cameo appearance to bolster his case against the controversial contemporary woman Clodia Metelli as one of the accusers of his client M. Caelius Rufus. This paper will consider questions raised by the iconography of the altar with reference to the development of Claudia's legend in Roman mythology and subsequently ask who was this Claudia the dedicator and why did she choose Magna Mater for her vow?

  2. Study on Seal Technology for Nuclear Material Control

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    The seals have important application in nuclear safeguards, and are designed to record unauthorizedaccess or entry to inspected material and equipment. They can provide assurance for the continuity andintegrity of nuclear material accountancy. It is very useful to improve the inspection efficiency by means

  3. RTC-control of power transients in nuclear reactors

    Energy Technology Data Exchange (ETDEWEB)

    Ratemi, Wajdi Mohamed [Alfateh University, PO Box 13040, Tripoli (Libyan Arab Jamahiriya)

    2006-07-01

    In this paper, the new Reactivity Trace Curve (RTC) method (Ratemi 1993,1994), which is based on the dynamic period studies (Bernard et al.,1984), has been studied for maneuvering of the nuclear reactor power without power shooting. The reactor is modeled with one group of delayed neutrons with temperature feedback effect, as well as, Xenon feedback effect. A precursors concentration model is used to provide for the effective dynamic decay constant (in one group case, it is a static one). The RTC-identifier which is given by a differential equation is then solved at each sampling time (for one group, it has an analytical solution). Its solution is what is called the Reactivity Trace Curve which keeps the power steady at the desired power. An inverse kinetic model which uses the on-line power data for reactivity calculation is used to provide initial condition (initial reactivity) for the RTC- power controller. Also feedback model are needed to evaluate both the temperature and Xenon reactivities which when subtracted from the RTC-value, one then can determine the reactivity required to keep the reactor power steady without power shooting. (authors)

  4. Electromagnetic Signature Technique as a Promising Tool to Verify Nuclear Weapons Storage and Dismantlement under a Nuclear Arms Control Regime

    Energy Technology Data Exchange (ETDEWEB)

    Bunch, Kyle J.; Williams, Laura S.; Jones, Anthony M.; Ramuhalli, Pradeep

    2012-08-01

    The 2010 ratification of the New START Treaty has been widely regarded as a noteworthy national security achievement for both the Obama administration and the Medvedev-Putin regime, but deeper cuts are envisioned under future arms control regimes. Future verification needs will include monitoring the storage of warhead components and fissile materials and verifying dismantlement of warheads, pits, secondaries, and other materials. From both the diplomatic and technical perspectives, verification under future arms control regimes will pose new challenges. Since acceptable verification technology must protect sensitive design information and attributes, non-nuclear non-sensitive signatures may provide a significant verification tool without the use of additional information barriers. The use of electromagnetic signatures to monitor nuclear material storage containers is a promising technology with the potential to fulfill these challenging requirements. Research performed at Pacific Northwest National Laboratory (PNNL) has demonstrated that low frequency electromagnetic signatures of sealed metallic containers can be used to confirm the presence of specific components on a “yes/no” basis without revealing classified information. Arms control inspectors might use this technique to verify the presence or absence of monitored items, including both nuclear and non-nuclear materials. Although additional research is needed to study signature aspects such as uniqueness and investigate container-specific scenarios, the technique potentially offers a rapid and cost-effective tool to verify reduction and dismantlement of U.S. and Russian nuclear weapons.

  5. Fuzzy-logic approach to HTR nuclear power plant model control

    Energy Technology Data Exchange (ETDEWEB)

    Bubak, M.; Moscinski, J. (Akademia Gorniczo-Hutnicza, Krakow (Poland)); Jewulski, J. (Institute of Physical Chemistry, Krakow (Poland))

    1983-01-01

    The fuzzy-set theory is used to incorporate linguistic 'rules of the thumb' of a human operator in the HTR nuclear power plant controller. The results of the extensive computer simulations are encouraging and confirm the usefulness of this approach in nuclear power plant control. In the Appendix, a short introduction to fuzzy logic is given.

  6. Fighting Obsolescence in the Nuclear Power Industry. Motor Control Centers-solutions and Case Study

    Energy Technology Data Exchange (ETDEWEB)

    Portillo, J.; Torralba Piqueras, A.

    2014-07-01

    Motor Control Centers (MCCs) are vital to the operation and control of nuclear power plants. A significant and growing problem within the global nuclear industry is the aging of MCC components. Obsolescence of various components within the MCCs such as molded case circuit breakers, starters, relays, heaters, transformers, etc., are impacting the reliability of MCCs to perform their intended safety function. (Author)

  7. 10 CFR 50.44 - Combustible gas control for nuclear power reactors.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Combustible gas control for nuclear power reactors. 50.44... FACILITIES Standards for Licenses, Certifications, and Regulatory Approvals § 50.44 Combustible gas control for nuclear power reactors. (a) Definitions—(1) Inerted atmosphere means a containment atmosphere...

  8. Investigation of control rod worth and nuclear end of life of BWR control rods

    Energy Technology Data Exchange (ETDEWEB)

    Magnusson, Per

    2008-01-15

    This work has investigated the Control Rod Worth (CRW) and Nuclear End of Life (NEOL) values for BWR control rods. A study of how different parameters affect NEOL was performed with the transport code PHOENIX4. It was found that NEOL, expressed in terms of {sup 10}B depletion, can be generalized beyond the conditions for which the rod is depleted, such as different power densities and void fractions, the corresponding variation in the NEOL will be about 0.2-0.4% {sup 10}B. It was also found that NEOL results for different fuel types and different fuel enrichments have a variation of about 2-3% in {sup 10}B depletion. A comparative study on NHOL and CRW was made between PHOENIX4 and the stochastic Monte Carlo code MCNP. It was found that there is a significant difference, both due to differences in the codes and to limitations in the geometrical modeling in PHOENIX4. Since MCNP is considered more physically correct, a methodology was developed to calculate the nuclear end of life of BWR control rods with MCNP. The advantages of the methodology are that it does not require other codes to perform the depletion of the absorber material, it can describe control rods of any design and it can deplete the control rod absorber material without burning the fuel. The disadvantage of the method is that is it time-consuming.

  9. Apuntes metodológicos de desarrollo orientado a agentes: Aplicación a una agencia de viajes.

    OpenAIRE

    Lázaro Molina, Jorge

    2006-01-01

    Apuntes metodológicos de desarrollo orientado a agentes con un ejemplo de aplicación a una agencia de viajes. Se centra en una ampliación de la metodología Gaia con AUML y algunas técnicas más. Además de su aplicación en la implementación mediante la plataforma JADE.

  10. Implementing nuclear non-proliferation in Finland. Regulatory control, international cooperation and the Comprehensive Nuclear-Test-Ban Treaty. Annual report 2011

    Energy Technology Data Exchange (ETDEWEB)

    Okko, O. (ed.)

    2012-07-01

    The regulatory control of nuclear materials (i.e. nuclear safeguards) is a prerequisite for the peaceful use of nuclear energy in Finland. Safeguards are required for Finland to comply with international agreements on nuclear non-proliferation - mainly the Non-Proliferation Treaty (NPT). This regulatory control is exercised by the Nuclear Materials Section of the Finnish Radiation and Nuclear Safety Authority (STUK). The results of STUK's nuclear safeguards inspection activities in 2011 continued to demonstrate that the Finnish licence holders take good care of their nuclear materials. There were no indications of undeclared nuclear materials or activities and the inspected materials and activities were in accordance with the licence holders' declarations.

  11. Información económica de Agencias Internacionales de Noticias: Impacto en la imagen de Venezuela

    Directory of Open Access Journals (Sweden)

    Nora Martínez

    2013-01-01

    Full Text Available El presente artículo tiene como objetivo analizar la influencia de las informaciones económicas generadas por las agencias internacionales de noticias sobre la imagen de Venezuela. Para lograr este propósito, se planteó un cuerpo teórico basado en diversos autores y se desarrolló una investigación descriptiva, cuya población estuvo integrada por periódicos de América Latina inscritos en la Sociedad Interamericana de Prensa (SIP, en especial los que mantienen suscripción con las agencias internacionales de noticias; siendo las unidades de información los editores y directores de la fuente de economía de dichos diarios. Los resultados arrojaron que las informaciones que difunden las agencias internacionales de noticias en Latinoamérica influyen en la formación de la imagen de Venezuela, partiendo de que el 70% de la muestra nunca ha visitado el país y que su opinión está basada en las informaciones económicas y políticas que recibe a diario de estas empresas noticiosas.Apartir de estas reseñas se generan opiniones sobre Venezuela con un matiz político, económico y social negativo, contrario a la percepción hacia sus habitantes basada en calidez y hospitalidad y en paisajes hermosos.

  12. Nonlinear Fuzzy Model Predictive Control for a PWR Nuclear Power Plant

    Directory of Open Access Journals (Sweden)

    Xiangjie Liu

    2014-01-01

    Full Text Available Reliable power and temperature control in pressurized water reactor (PWR nuclear power plant is necessary to guarantee high efficiency and plant safety. Since the nuclear plants are quite nonlinear, the paper presents nonlinear fuzzy model predictive control (MPC, by incorporating the realistic constraints, to realize the plant optimization. T-S fuzzy modeling on nuclear power plant is utilized to approximate the nonlinear plant, based on which the nonlinear MPC controller is devised via parallel distributed compensation (PDC scheme in order to solve the nonlinear constraint optimization problem. Improved performance compared to the traditional PID controller for a TMI-type PWR is obtained in the simulation.

  13. Progress of nuclear safety for symbiosis and sustainability advanced digital instrumentation, control and information systems for nuclear power plants

    CERN Document Server

    Yoshikawa, Hidekazu

    2014-01-01

    This book introduces advanced methods of computational and information systems allowing readers to better understand the state-of-the-art design and implementation technology needed to maintain and enhance the safe operation of nuclear power plants. The subjects dealt with in the book are (i) Full digital instrumentation and control systems and human?machine interface technologies (ii) Risk? monitoring methods for large and? complex? plants (iii) Condition monitors for plant components (iv) Virtual and augmented reality for nuclear power plants and (v) Software reliability verification and val

  14. Los despachos de agencia (teletipos como tipo documental Agency dispatches (teletypes as a documentary type

    Directory of Open Access Journals (Sweden)

    Jorge Caldera Serrano

    2007-06-01

    Full Text Available Se analiza el despacho de agencia como tipo documental que debe ser conservado y analizado por parte de los departamentos de documentación de los medios de comunicación tanto de prensa escrita como audiovisuales y sonoros. Para llevar a cabo dicho análisis se realiza un estudio sobre su estructura semántica discursiva que sirva como base para la identificación de los puntos de acceso con los que debe contar la base de datos que albergue dicho material: información temática; cronológica, geográfica y onomástica.An agency's dispatch is analyzed as a documentary type (print, audiovisual and sound material which must be preserved and analyzed by the documentation departments of the mass media. In order to carry out such analysis, a study of the semantic structure of their discourse is made to serve as a basis for the identification of access points that the data base requires if it is to store such material: subject, chronological, geographic and author information.

  15. Del sujeto a la agencia (a través de lo político

    Directory of Open Access Journals (Sweden)

    José Enrique Ema López

    2004-05-01

    Full Text Available Este trabajo tiene su campo de preocupaciones en la ?trastienda? de la teorización social sobre la acción política. Y aunque tomamos como punto de partida la imposibilidad de fundamentar la acción política en el sujeto universal del Racionalismo y Humanismo moderno, pretendemos hacer compatible un conjunto de críticas a este Humanismo y Racionalismo con una apuesta y compromiso con algunas de las propuestas emancipatorias de la modernidad. Así, presentaremos dos formas de abordar las tensiones provocadas por el privilegio del sujeto de la modernidad para pensar en la política. Una de ellas se centrará en su politización radical, introduciendo al sujeto como territorio y consecuencia de la propia acción. Otra, presenta la noción de agencia como privilegio de las conexiones y los movimientos frente a las (identidades, para explicar la acción.

  16. Human factors design review guidelines for advanced nuclear control room technologies

    Energy Technology Data Exchange (ETDEWEB)

    O' Hara, J.; Brown, W. (Brookhaven National Lab., Upton, NY (United States)); Granda, T.; Baker, C. (Carlow Associates, Inc., Fairfax, VA (United States))

    1991-01-01

    Advanced control rooms (ACRs) for future nuclear power plants are being designed utilizing computer-based technologies. The US Nuclear Regulatory Commission reviews the human engineering aspects of such control rooms to ensure that they are designed to good human factors engineering principles and that operator performance and reliability are appropriately supported in order to protect public health and safety. This paper describes the rationale, general approach, and initial development of an NRC Advanced Control Room Design Review Guideline. 20 refs., 1 fig.

  17. A rhomboid gene controls speciation through regulation of nuclear-mitochondrial compatibility in Triticum

    Science.gov (United States)

    The nuclear encoded species cytoplasm specific (scs) genes control nuclear-cytoplasmic compatibility in Triticum. Alloplasmic cells, which have nucleus and cytoplasm derived from different species, produce vigorous and vital organisms only when the correct version of scs is present in their nucleus....

  18. Controlling the Proliferation of Nuclear Weapons: Study Guide for Teachers and Students

    Science.gov (United States)

    United States Institute of Peace, 2005

    2005-01-01

    The objectives of this teaching guide are: (1) to increase student understanding of the prevalence and spread of nuclear weapons; (2) to familiarize students with historic and contemporary measures to control nuclear proliferation and stimulate their thinking of potential strategies for doing so in the future; (3) to develop students' analytical…

  19. Tumefactive immunoglobulin G4-related disease involving the dura mater: A case report and literature review

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jeong Hoon; Lee, Ji Hoon; Ko, Yong; Paik, Seoung Sam; Lee, Young Jun [Dept. of Radiology, Hanyang University Hospital, Seoul (Korea, Republic of); Park, Dong Woo [Dept. of Radiology, Hanyang University Hospital, Seoul (Korea, Republic of)

    2015-08-15

    Immunoglobulin G4 (IgG4)-related disease is a well-known disorder characterized by an inflammatory reaction with an increase in the number of IgG4-positive plasma cells associated with sclerosis. IgG4-related disease often affects the dura mater with a pattern of diffuse thickening when the central nervous system is involved. However, some nodular dural thickening requires discrimination from tumors because of obviously different treatment options. We report of a case of IgG4-related disease with tumefactive dural involvement.

  20. VARSTVO DELAVK MATER V LUČI NOVEJŠE SODNE PRAKSE EU

    OpenAIRE

    2011-01-01

    Uskladiti poklicno in družinsko življenje je velik izziv za delavke matere, sploh v današnjem času, ko sta v večini primerov zaposlena tako oče kot mati. Cilj na področju delovnega prava je zato zagotavljati delavkam materam posebno varstvo. S tem je mišljeno predvsem varstvo pred prekinitvijo poklicne poti zaradi materinstva. Veliko žensk se zanj namreč ne odloča ravno z razlogom bojazni pred odpovedjo pogodbe o zaposlitvi s strani delodajalca ter kolebanjem med materinstvom in kariero. Dipl...

  1. Nuclear RNA surveillance: role of TRAMP in controlling exosome specificity.

    Science.gov (United States)

    Schmidt, Karyn; Butler, J Scott

    2013-01-01

    The advent of high-throughput sequencing technologies has revealed that pervasive transcription generates RNAs from nearly all regions of eukaryotic genomes. Normally, these transcripts undergo rapid degradation by a nuclear RNA surveillance system primarily featuring the RNA exosome. This multimeric protein complex plays a critical role in the efficient turnover and processing of a vast array of RNAs in the nucleus. Despite its initial discovery over a decade ago, important questions remain concerning the mechanisms that recruit and activate the nuclear exosome. Specificity and modulation of exosome activity requires additional protein cofactors, including the conserved TRAMP polyadenylation complex. Recent studies suggest that helicase and RNA-binding subunits of TRAMP direct RNA substrates for polyadenylation, which enhances their degradation by Dis3/Rrp44 and Rrp6, the two exosome-associated ribonucleases. These findings indicate that the exosome and TRAMP have evolved highly flexible functions that allow recognition of a wide range of RNA substrates. This flexibility provides the nuclear RNA surveillance system with the ability to regulate the levels of a broad range of coding and noncoding RNAs, which results in profound effects on gene expression, cellular development, gene silencing, and heterochromatin formation. This review summarizes recent findings on the nuclear RNA surveillance complexes, and speculates upon possible mechanisms for TRAMP-mediated substrate recognition and exosome activation.

  2. Lessons from UNSCOM/IAEA applicable to nuclear arms control

    Energy Technology Data Exchange (ETDEWEB)

    Dorn, D.W.

    1995-12-05

    In early 1991, the Security Council of the United Nations tasked the Director General of the International Atomic Energy Agency, with the assistance and cooperation of the United Nations Special Commission, to oversee the destruction, removal or rendering harmless of nuclear weapons material and capabilities in Iraq. The conduct of the nuclear inspections, and the subsequent activities (identification, destruction, removal rendering harmless), have provided a wealth of experience and insight into the inspection and monitoring process as well as into the political realities of such an operation. The early inspections were conducted in an atmosphere of discovery and inexperience on both the part of the Iraqis and the IAEA and UNSCOM. As time went on, the Iraqis became more adept at hiding and obscuring relevant documents and equipment, and the inspection teams became more knowledgeable about inspection and investigative techniques, and the pre-existing Iraqi programs. A continuous monitoring presence in Iraq has now been established and an import/export monitoring regime is being developed. While steps taken to date have proven effective in inhibiting resumption of nuclear weaponization activities, it remains to be seen how effective these measures will be in the future. The external and internal conditions which led the Iraqi leadership to undertake a nuclear weaponization program have not changed, and the prognosis for the long term is uncertain. The entire process in Iraq has shown how fragile are the tools available to the international community, and how a determined proliferator can evade inspection and monitoring measures. Such measures cannot prevent nuclear proliferation, they can only hope to deter it, or, failing in that, detect it.

  3. O Goodwill na Avaliação de Empresas: Um Estudo Sobre a Realização de Testes de Imparidades e as Alterações Contabilísticas no Âmbito das Concentrações de Atividades Empresariais

    Directory of Open Access Journals (Sweden)

    Thiago de Sousa Barros

    2013-07-01

    Full Text Available Este artigo descreve as principais alterações introduzidas no normativo contabilístico internacional no que tange ao goodwill e suas eventuais implicações na informação contabilística divulgada. Ademais, este trabalho caracteriza os intangíveis sem condições de reconhecimento, com destaque para o goodwill, suas especificidades, as controvérsias reinantes entre pesquisadores no tocante à sua contabilização, enfatizando, neste prisma, a necessidade de realização dos testes de imparidade. Nessa esfera, o presente artigo centra-se em analisar a polêmica da determinação da taxa de desconto, estudar o conceito de justo valor e observar a relação entre contabilidade e as técnicas de avaliação de empresas. Por fim, este trabalho lança luz à importância da adoção dessas normas por países como Portugal e Brasil, a fim de garantir uma informação financeira com alto índice de relevância e fiabilidade, afinal as informações divulgadas pelas empresas ajudam os usuários das Demonstrações Financeiras Consolidadas a avaliar a natureza, os riscos e os efeitos financeiros associados às concentrações de atividades empresariais e ao goodwill, aspectos estes de extrema importância para a tomada de decisões.

  4. Superradiant control of gamma-ray propagation by vibrating nuclear arrays

    CERN Document Server

    Zhang, Xiwen

    2013-01-01

    The collective nature of light interactions with atomic and nuclear ensembles yields the fascinating phenomena of superradiance and radiation trapping. We study the interaction of gamma rays with a coherently vibrating periodic array of two-level nuclei. Such nuclear motion can be generated, e.g., in ionic crystals illuminated by a strong driving optical laser field. We find that deflection of the incident gamma beam into the Bragg angle can be switched on and off by nuclear vibrations on a superradiant time scale determined by the collective nuclear frequency, which is of the order of terahertz. Namely, if the incident gamma wave is detuned from the nuclear transition by much larger frequency it passes through the static nuclear array. However, if the nuclei vibrate with the frequency of the gamma ray detuning then parametric resonance can yield energy transfer into the Bragg deflected beam on the superradiant time scale, which can be used for fast control of gamma rays.

  5. Design concepts for a nuclear digital instrumentation and control system platform

    Energy Technology Data Exchange (ETDEWEB)

    Ou, T. C.; Chen, C. K.; Chen, P. J.; Shyu, S. S.; Lee, C. L. [Institute of Nuclear Energy Research, Atomic Energy Council, No. 1000 Wenhua Rd., Jiaan Village, Longtan Township, Taoyuan County 32546 Taiwan (China); Hsieh, S. F., E-mail: tcou@iner.gov.t [Electronics Group, Formosa Plastics Co., 100 Sue-Guan Road, Jen-Wu Hsiang, Kaohsiung County, Taiwan (China)

    2010-10-15

    The objective of this paper is to present the development results of the nuclear instrumentation and control system in Taiwan. As the Taiwan nuclear power plants age, the need to consider upgrading of both their safety and non-safety-related instrumentation and control systems becomes more urgent. Meanwhile, the digital instrumentation and control system that is based on current fast evolving electronic and information technologies are difficult to maintain effectively. Therefore, Institute of Nuclear Energy Research was made a decision to promote the Taiwan Nuclear Instrumentation and Control System project to collaborate with domestic electronic industry to establish self-reliant capabilities on the design, manufacturing, and application of nuclear instrumentation and control systems with newer technology. In the case of safety-related applications like nuclear instrumentation and control, safety-oriented quality control is required. In order to establish a generic qualified digital platform, the world-wide licensing experience should be considered in the licensing process. This paper describes the qualification and certification tools by IEC 61508 for design and development of safety related equipment and explains the basis for many decisions made while performing the digital upgrade. (Author)

  6. A organizaçâo contabilística no sector conserveiro entre o final do século XIX e a primeira metade do século XX: o caso Júdice Fialho = The accounting model in the Portuguese canned-fish industry between the end of the 19th century and the first...

    Directory of Open Access Journals (Sweden)

    Ana Rita Faria

    2011-12-01

    evolution of accounting practices in Portugal, namely studies based on the analysis of surviving business records of firms, justifies this study.The study concludes that, in the absence of a set of accounting principles and procedures available to all enterprises, the management of Júdice Fialho sought to adopt, from within the varied material available at the time, those accounting techniques which were most relevant to their business operations and actual needs at that time. During the period under examination, the company’s accounting records did not suffer significant changes. The formation as a partnership in 1938, four years after the death of its founder, could have acted has a stimulus for change, but that didn’t happen.Este estudo tem por objectivo analisar a organização contabilística de uma das maiores empresas da indústria de conservas de peixe portuguesa, a Júdice Fialho, entre o final do século XIX e a primeira metade do século XX. Pretende ainda confrontar a organização contabilística existente na empresa com os modelos divulgados na literatura contabilística portuguesa publicada no mesmo período.A justificação para a sua realização residiu na escassez de estudos baseados na análise de registos contabilísticos originais e na disponibilidade, no Arquivo Histórico do Museu Municipal de Portimão (Algarve, de documentação contabilística relativa a esta grande empresa. O estudo conclui que, na ausência de um conjunto de regras e princípios de Contabilidade comuns as todas as empresas, a Júdice Fialho procurou adoptar, considerando a diversidade de soluções contabilísticas divulgadas na literatura da especialidade, a mais adequada às suas características e necessidades reais. A contabilidade da empresa está organizada para fornecer informação sobre os resultados particulares de cada segmento organizacional (fábrica, secção, oficina, depósito, … e não sobre os lucros ou prejuízos obtidos na venda dos diversos produtos

  7. An improved implicit multiple model predictive control used for movable nuclear power plant

    Energy Technology Data Exchange (ETDEWEB)

    Tai Yun, E-mail: nalren@stu.xjtu.edu.c [School of Energy and Power Engineering, Xi' an Jiaotong University, Xi' an Shaanxi, 710049 (China); Hou Suxia, E-mail: hsxhjj@sina.com.c [School of Energy and Power Engineering, Xi' an Jiaotong University, Xi' an Shaanxi, 710049 (China); Li Chong, E-mail: abcdirxj@stu.xjtu.edu.c [School of Energy and Power Engineering, Xi' an Jiaotong University, Xi' an Shaanxi, 710049 (China); Zhao Fuyu, E-mail: fyzhao@mail.xjtu.edu.c [School of Energy and Power Engineering, Xi' an Jiaotong University, Xi' an Shaanxi, 710049 (China)

    2010-10-15

    Compared with the nuclear power station, the movable nuclear plant has the special requirement of the load following ability and is more difficult to control. In this work, a MMPC (multiple model predictive control) method is applied to the power system of the movable nuclear plant. The linear models used to describe the power changing process, according to which the local controllers are designed, still suffer rough switching. In this paper, work has been done on the improvement of MMPC to make it better in application to the power system of the movable nuclear plant. The simulation results show that these modifications are available to improve the system's dynamic characters, and the multiple strategy is efficacious to solve the control problem of the parameter time-variable nonlinear system.

  8. Comparison of Hazard Analysis Requirements for Instrumentation and Control System of Nuclear Power Plants

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jang Soo [KAERI, Daejeon (Korea, Republic of); Yoo, Jun Beom [Konkuk University, Seoul (Korea, Republic of)

    2014-08-15

    A hazard, in general, is defined as 'potential for harm.' In this paper, the scope of 'harm' is limited to the loss of a safety function in a Nuclear Power Plant (NPP). The Hazard Analysis (HA) of an Instrumentation and Control (I and C) systems is to identify the relationship from the logical faults, error, and failure of I and C systems to the physical harm of the nuclear power plant, and also to find the impact of the external hazard, e.g., tsunami, of the nuclear power plant to the I and C systems. This paper includes the survey of the existing hazard analysis requirements in the nuclear industries. The purpose of the paper is to compare the HA requirements in various international standards in unclear domain, specifically the safety requirements and guidance for the instrumentation and control system for the nuclear power plant from IAEA, IEC, IEEE, and NRC.

  9. Publicidad para inmigrantes en España. Un estudio desde las agencias

    Directory of Open Access Journals (Sweden)

    Antonio-J. Baladrón-Pazos

    2011-01-01

    Full Text Available En este artículo se aborda la situación actual y el futuro de la publicidad para inmigrantes en España. Se recogen los resultados de una investigación tipo Delphi realizada en 2009 y 2010 entre directivos de las agencias étnicas. El objetivo principal fue llevar a cabo un análisis sobre las tendencias que, según estos directivos, caracterizarán la publicidad para inmigrantes en los próximos años y sobre cómo realmente ellos desearían que evolucionase esta publicidad. Se reflexiona sobre la necesidad que tienen las empresas de orientar su comunicación a una sociedad cada vez más traspasada por la diversidad cultural, debido al notable crecimiento de la inmigración en la España de los últimos años. Entre las conclusiones obtenidas, destaca que en el futuro la publicidad para inmigrantes pasará por un mayor grado de creatividad, de utilización de la Web 2.0., de profesionalización del sector y de investigación sobre este segmento. También se platea como hipótesis de futuro que en esta publicidad sea cada vez menos relevante la dimensión étnica, teniendo menos importancia los referentes culturales de los orígenes de los inmigrantes. Esto será debido que los nuevos residentes estarán cada vez más integrados en la sociedad española y serán cada vez más incorporados a la planificación de todo tipo de campañas.

  10. Factores determinantes y coste económico del absentismo de pacientes en consultas externas de la Agencia Sanitaria Costa del Sol

    Directory of Open Access Journals (Sweden)

    M.L. Jabalera Mesa

    2015-08-01

    Full Text Available Fundamento: Identificar los factores de la persona, el proceso y el contexto que influyen en el cumplimiento de las citas de consultas externas en la Agencia Sanitaria Costa del Sol, describiendo el perfil del paciente que no acude a su cita, los motivos del absentismo y realizando una estimación del coste económico. Método: Estudio observacional, multicéntrico de casos y controles, mediante encuesta a pacientes citados en consultas ambulatorias durante 2013 y 2014 y análisis de costes por consultas. Resultados: Participaron en el estudio 882 pacientes (294 casos y 588 controles. El olvido (29,6%; n=87 y el fallo en la comunicación (16%; n=47, fueron los principales motivos manifestados por los pacientes absentistas. Una menor demora en la cita y la edad avanzada se asociaban significativamente con menos ausencias, al igual que haber frecuentado más las consultas en el último año. El coste económico fue superior a 3 millones de euros para una tasa de inasistencia del 13,8%. Conclusiones: Los pacientes jóvenes que no frecuentan habitualmente las consultas constituyen el grupo de mayor riesgo de ausencia a las citas programadas en nuestra área sanitaria. Los principales motivos del absentismo son evitables y podrían beneficiarse de intervenciones como la mejora de los procedimientos de comunicación o sistemas de recordatorio de citas.

  11. Nuclear RNA Surveillance: Role of TRAMP in Controlling Exosome Specificity

    OpenAIRE

    Schmidt, Karyn; Butler, J. Scott

    2013-01-01

    The advent of high throughput sequencing technologies has revealed that pervasive transcription generates RNAs from nearly all regions of eukaryotic genomes. Normally these transcripts undergo rapid degradation by a nuclear RNA surveillance system primarily featuring the RNA exosome. This multimeric protein complex plays a critical role in the efficient turnover and processing of a vast array of RNAs in the nucleus. Despite its initial discovery over a decade ago, important questions remain c...

  12. Antecedents to and outcomes of Rh(D) isoimmunization: Mater Mothers Hospital, Brisbane, 1988-1995.

    Science.gov (United States)

    Portmann, C; Ludlow, J; Joyce, A; Chan, F Y

    1997-02-01

    We analyzed the antecedents and outcomes of Rh(D) isoimmunization in a local population. Forty-two Rh(D) isoimmunized women attending Mater Mothers Hospital for antenatal care were identified through the Mater Hospital Blood Bank database; their records were reviewed for variables including sensitizing events, obstetric interventions and pregnancy outcomes. In this group, 74% of women became sensitized despite receiving anti-D immune globulin, 17% did not receive anti-D appropriately and the other failed to attend for treatment of bleeding in pregnancy. Antenatal sensitization was implicated in 6 women (14%) and potentially responsible for isoimmunization in another 18. Over half of the 80 viable pregnancies in this study group required some form of obstetric intervention. Thirty pregnancies required amniocentesis and 1 in 3 babies underwent either intrauterine or exchange transfusion. Three fetal deaths occurred as a result of severe disease. This study offers information highlighting circumstances in which immunoprophylaxis guidelines have failed to impart protection against Rh(D) sensitization and the consequences of such failures.

  13. Use of equine pericardium sheet (LYOMESH®) as dura mater substitute in endoscopic endonasal transsphenoidal surgery

    Science.gov (United States)

    Cavallo, Luigi M.; Solari, Domenico; Somma, Teresa; Di Somma, Alberto; Chiaramonte, Carmela; Cappabianca, Paolo

    Objective The aim of this study was to describe the use of equine pericardium sheet (Lyomesh ® ) as dural substitute for sellar reconstruction after endoscopic endonasal transsphenoidal surgery for the removal of pituitary adenomas. Methods We reviewed data of patients that underwent surgery by means of an endoscopic endonasal transsphenoidal approach for the removal of pituitary adenomas over a 12-months period, starting in May 2012, i.e. when we adopted Lyomesh ® (Audio Technologies, Piacenza, Italy) an equine pericardium sheet, as dura mater substitute. Results: During the 12-months period evaluated, we performed an endoscopic endonasal transsphenoidal operation for a variety of pituitary lesions on 102 consecutive patients. Among these, in 12 patients (9.4%) harboring a pituitary adenoma, the implant of the pericardium sheet was used. Four patients (33.3%) presented a small intraoperative cerebrospinal fluid (CSF) leak; in these cases the Lyomesh ® was placed intradurally with fibrin glue and, thereafter, several layers were positioned in extradural space. In 8 other subjects without any evidence of CSF leak, the dural substitute was placed intradurally and fibrin glue was injected intradurally to hold the material in place. Conclusions: Even if based on a relatively small patient series, our experience demonstrated that the use of equine pericardium sheet (Lyomesh ® ) as dura mater substitute in transsphenoidal surgery is safe and biocompatible, as compared with other dural substitutes. PMID:24251248

  14. Control of radioactive waste in dismantling of a nuclear facility; Control de residuos radiactivos en desmantelamiento de una instalacion nuclear

    Energy Technology Data Exchange (ETDEWEB)

    Campayo, E.

    2014-07-01

    In the dismantling of a nuclear facility are generated radioactive waste that must be suitably processed. The overall process, in a simplified manner, contemplates the characterization in origin, their segregation on the basis of physical, mechanical, and radiological characteristics and their packaging. (Author)

  15. MATER - Pianeta Terra-Mare: an interactive and multidisciplinary approach to Geosphere sciences

    Science.gov (United States)

    Piangiamore, Giovanna Lucia; Fanelli, Emanuela; Furia, Stefania; Garau, Daniela; Merlino, Silvia; Musacchio, Gemma; Carla Centineo, Maria

    2016-04-01

    Recent studies demonstrate that Earth and Marine Sciences are not properly treated in scholastic programs and in textbooks are included in a superficial way. These topics are interdisciplinary and experimental (biology, ecology, oceanography and geology) and the recent advance in these fields is strictly linked to technologic improvement. School cannot keep up with the huge advances of knowledge experimented in the last 20 years, also for the lack of didactic laboratories sufficiently updated to support experimental activities. In this context, in 2014-15 three Italian Research Institutes (INGV, ISMAR-CNR and ENEA-CRAM) have decided to support the Unified School District "ISA 10"of Lerici (Liguria, Italy) - comprehensive of kindergartner, primary and middle schools - to develop the project MATER - Pianeta Terra-Mare (Planet Earth and Sea). The acronym MATER (MARe and TERra) has also a gender value, as people involved in the projects were women, mostly researchers and teachers, which have worked side by side with other women belonging to environmental and cultural associations of the territory. This heterogeneous group has a common objective: to promote the diffusion of a scientific culture and to sensitize students from 3 to 14 years towards problems occurring in marine and terrestrial environments, fostering the settlement of a sustainable attitude to the exploitation of natural resources and consciousness to natural hazards, such as earthquakes and floods, quite common in the Ligurian region. MATER has been considered as one of the best projects funded by MIUR (Italian Ministry of Education, University and Research) inside the Dissemination of Scientific and Technological Culture call for the year 2014. Natural hazards (Planet Earth) and the chemical-physical aspects and resources of the marine environment (Planet Sea) were the two modules of the project. Planet Earth developed through Piovono Idee! (Cloudy with a chance of Ideas!), an interactive exhibition on

  16. Adaptive Neural Network Algorithm for Power Control in Nuclear Power Plants

    Science.gov (United States)

    Masri Husam Fayiz, Al

    2017-01-01

    The aim of this paper is to design, test and evaluate a prototype of an adaptive neural network algorithm for the power controlling system of a nuclear power plant. The task of power control in nuclear reactors is one of the fundamental tasks in this field. Therefore, researches are constantly conducted to ameliorate the power reactor control process. Currently, in the Department of Automation in the National Research Nuclear University (NRNU) MEPhI, numerous studies are utilizing various methodologies of artificial intelligence (expert systems, neural networks, fuzzy systems and genetic algorithms) to enhance the performance, safety, efficiency and reliability of nuclear power plants. In particular, a study of an adaptive artificial intelligent power regulator in the control systems of nuclear power reactors is being undertaken to enhance performance and to minimize the output error of the Automatic Power Controller (APC) on the grounds of a multifunctional computer analyzer (simulator) of the Water-Water Energetic Reactor known as Vodo-Vodyanoi Energetichesky Reaktor (VVER) in Russian. In this paper, a block diagram of an adaptive reactor power controller was built on the basis of an intelligent control algorithm. When implementing intelligent neural network principles, it is possible to improve the quality and dynamic of any control system in accordance with the principles of adaptive control. It is common knowledge that an adaptive control system permits adjusting the controller’s parameters according to the transitions in the characteristics of the control object or external disturbances. In this project, it is demonstrated that the propitious options for an automatic power controller in nuclear power plants is a control system constructed on intelligent neural network algorithms.

  17. LA AGENCIA DE LA NIÑA Y EL NIÑO EN LA CONDICIÓN PRE-CIUDADANA

    Directory of Open Access Journals (Sweden)

    Marcela González Coto

    2012-01-01

    Full Text Available El presente ensayo se deriva del trabajo que recientemente han desarrollado la Fundación PANIAMOR y la Dirección General del Programa CEN-CINAI del Ministerio de Salud, sobre la formación ciudadana de los niños y las niñas costarricenses en la primera infancia. Las acciones conjuntas se han enfocado en la capacidad de agencia de los niños y las niñas, entendida como la disposición para explorar, reflexionar, actuar y valorarse en sus entornos como sujetos políticos. Para este fin, en este ensayo se lleva a cabo un análisis crítico de los modelos ideológicos y culturales que, en la sociedad contemporánea, legitiman y fomentan la condición de "pre-ciudadanía" de la infancia, mermando su desempeño, presente y futuro, como ciudadanos plenos de la sociedad. El análisis se sustenta en materiales diversos, de distintos orígenes, todos relativos a las condiciones actuales de la infancia y las formas como se restringen estas capacidades de agencia. El ensayo también aborda las dificultades y obstáculos que enfrenta un replanteamiento de las relaciones entre adultos y niños. También se documentan los esfuerzos recientes, tanto locales como internacionales, para crear marcos alternativos desde los cuales replantear la relación institucional entre unos y otros. Como principal resultado del ensayo, se delinean un conjunto de directrices, con expresión curricular, que pueden sustentar el desarrollo de las capacidades de agencia infantil con una manifestación directa en la niñez ciudadana, la cual, se plantea, se articula en tres dimensiones o ejes de desarrollo (la responsabilidad, la autonomía y el pensamiento complejo.

  18. Teoría de agencia: una revisión del origen biológico del delito

    OpenAIRE

    Iván Araya; Crespo, Fernando A.

    2016-01-01

    Este trabajo aborda la causa del conflicto entre principal y agente, buscando respuestas en las disciplinasde la biología, particularmente en las ciencias de la antropología criminal. Se ha realizado un ensambleentre los hallazgos de la teoría de agencia y la teoría de los delitos de cuello blanco, reinterpretando lasactuaciones del agente desde su configuración entre instinto, herencia y personalidad. Los resultadosen las ciencias biológicas podrían aportar nuevas interpretaciones y explicac...

  19. La gestión pública a través de agencias: experiencias europeas

    OpenAIRE

    1993-01-01

    Este artículo tiene por objeto analizar las recientes experiencias de gestión a través de agencias en las administraciones públicas europeas. Comienza por revisar la evolución del caso sueco, donde este modelo cuenta con una larga tradición histórica. A continuación, se contempla con cierto detalle el programa «Next Steps», por el que se adopta el citado esquema organizativo en la Administración británica. Por último, nos detendremos en la experiencia francesa, más modesta en sus aspiraciones...

  20. Emociones, agencia y experiencia escolar: el papel de los vínculos en los procesos de inclusión escolar en el nivel secundario

    Directory of Open Access Journals (Sweden)

    Mariana Nobile

    2014-04-01

    Full Text Available Desde hace unos años venimos explorando el modo en que la dimensión emocional de la experiencia escolar interviene en los procesos de inclusión-exclusión educativa en el nivelsecundario. Aquí analizamos en profundidad las entrevistas realizadas a 16 jóvenes de sectores populares que han egresado de las llamadas “Escuelas de Reingreso” en las que se indagaron las formas en que ellos enunciaban su experiencia emocional, explorando lasfuentes de dicha emocionalidad. Respeto, entusiasmo y tranquilidad fueron lasformas enunciativas utilizadas para describir sus experiencias. Nuestra hipótesis es que el tipo de vínculos construidos con los docentes en el marco de un formato escolar particular genera una emocionalidad positiva, que permite resignificar la trayectoria escolar personal, reposicionarse frente a la institución escolar y potenciar su sensación de agencia, en términos de sentirse con mayores márgenes de control acerca de su propia vida, permitiéndole de este modo desplegar diferentes tipos de estrategias personales para su integración laboral, educativa y familiar.

  1. Externalización de la gestión documental audiovisual en las televisiones por medio de productoras audiovisuales y agencias de noticias

    Directory of Open Access Journals (Sweden)

    Jorge CALDERA-SERRANO

    Full Text Available Se analiza la simplificación en el método de análisis de contenido en los archivos televisivos derivados de factores diversos tales como la reestructuración de la organización documental, los ajustes de los recursos humanos y económicos así como la adquisición de la descripción de análisis del contenido a empresas creadoras de contenidos tales como las productoras y las agencias de noticias audiovisuales. Ambos factores, de forma simbiótica, han modificado la descripción documental eliminando la descripción de contenido temático, geográfico y onomástico así como el control terminológico y documental por medio de herramientas propias del lenguaje documental. Estos cambios se traducen en graves problemas de normalización y recuperación que no parecen solventados por medio de técnicas para la identificación automática de contenido audiovisual (herramientas biométricas.

  2. 10 CFR 50.34a - Design objectives for equipment to control releases of radioactive material in effluents-nuclear...

    Science.gov (United States)

    2010-01-01

    ... radioactive material in effluents-nuclear power reactors. 50.34a Section 50.34a Energy NUCLEAR REGULATORY... objectives for equipment to control releases of radioactive material in effluents—nuclear power reactors. (a... equipment to be installed to maintain control over radioactive materials in gaseous and liquid...

  3. OVERVIEW OF A RECONFIGURABLE SIMULATOR FOR MAIN CONTROL ROOM UPGRADES IN NUCLEAR POWER PLANTS

    Energy Technology Data Exchange (ETDEWEB)

    Ronald L. Boring

    2012-10-01

    This paper provides background on a reconfigurable control room simulator for nuclear power plants. The main control rooms in current nuclear power plants feature analog technology that is growing obsolete. The need to upgrade control rooms serves the practical need of maintainability as well as the opportunity to implement newer digital technologies with added functionality. There currently exists no dedicated research simulator for use in human factors design and evaluation activities for nuclear power plant modernization in the U.S. The new research simulator discussed in this paper provides a test bed in which operator performance on new control room concepts can be benchmarked against existing control rooms and in which new technologies can be validated for safety and usability prior to deployment.

  4. Delayed entanglement echo for individual control of a large number of nuclear spins

    Science.gov (United States)

    Wang, Zhen-Yu; Casanova, Jorge; Plenio, Martin B.

    2017-03-01

    Methods to selectively detect and manipulate nuclear spins by single electrons of solid-state defects play a central role for quantum information processing and nanoscale nuclear magnetic resonance (NMR). However, with standard techniques, no more than eight nuclear spins have been resolved by a single defect centre. Here we develop a method that improves significantly the ability to detect, address and manipulate nuclear spins unambiguously and individually in a broad frequency band by using a nitrogen-vacancy (NV) centre as model system. On the basis of delayed entanglement control, a technique combining microwave and radio frequency fields, our method allows to selectively perform robust high-fidelity entangling gates between hardly resolved nuclear spins and the NV electron. Long-lived qubit memories can be naturally incorporated to our method for improved performance. The application of our ideas will increase the number of useful register qubits accessible to a defect centre and improve the signal of nanoscale NMR.

  5. Structural control of the stability of nuclear waste glasses

    Science.gov (United States)

    Calas, G.; Galoisy, L.; Cormier, L.; Bergeron, B.; Jollivet, P.

    2009-05-01

    Vitrification of liquid high-level radioactive waste in borosilicate glasses has received a great attention in several countries. The fundamental properties of the waste forms are their chemical and mechanical durability. We present an overview of the local structure of inactive analogs of the French nuclear glass, using structural information obtained by a combination of X-ray absorption Fine Structure (XAFS) and Wide Angle X-ray Scattering (WAXS). We will first contrast several classes of elements, such as Zr, Mo or Zn, which give nuclear glasses peculiar positive or adverse properties for the industrial process: enhanced chemical stability, phase separation, crystal nucleation and separation. These properties may be rationalized using Pauling rules, familiar to Mineralogists, as other properties are correctly modelled in simplified glass compositions using molecular dynamics. We will also point out the importance of the melt-to-glass transition and the consequence of the glass structural properties on the resistance of glassy matrices to irradiation. Glass alteration affects the long-term stability of the glass. It is characterized by an amorphous (glass)-amorphous (gel) transformation. Depending on alteration conditions, alteration layers may have or not a protective character, which will influence radionuclide retention over time. We will present the structural modification of the surface chemistry of the glass monoliths during short-term experiments and the evolution towards a gel, which forms progressively at the expense of the glass. The protective character of the gel, observed during glass leaching under near-saturated conditions, will be rationalized by its structural properties.

  6. Malfunction analysis response system (MARS) for nuclear power plants control rooms

    Energy Technology Data Exchange (ETDEWEB)

    Peters, F.; Rossmann, D.L.

    1984-01-01

    Whenever the need for the safe and reliable operation of a complex system exists, a major requirement for success is the actions of the people involved. This is especially true when a time-critical response is required. In this context, the operation of a nuclear power plant is exemplary. Lessons from the Three Mile Island-2 incident show that insufficient attention was paid to the man/machine interface. Since that time, considerable effort has been directed by the nuclear industry toward the improvement of control room instrumentation, emergency operating procedures, and operator training. The improvement of the safety of nuclear power plants through the reduction of operator errors is discussed. The nuclear power plant operator's diagnostic role is analogous to that of a flight controller for a manned space flight mission. Both must be able to quickly understand and integrate large quantities of information on current system operation with background data on system design and performance.

  7. Control flow of radiopharmaceuticals in nuclear medicine by means of an E-service; Control flujo de radiofarmacos en medicine nuclear por medio de un E-servicio

    Energy Technology Data Exchange (ETDEWEB)

    Nunez Martin, L.; Gonzalez de Mingo, M. A.; Fragua Redondo, J. A.; Martinez Ortega, J.; Gutierrez Camunas, S.; Redondo Miguel, A. B.

    2013-07-01

    The almost generalized use of single-dose Nuclear Medicine for performing diagnostic tests or treatments, and the consequent complexity that accompanies its management, has resulted in the need to control the flow of material radioisotopic tools. An e-service is designed to manage the flow of radiopharmaceuticals and control its use and spending. This control does not only affect the efficiency in the use and cost of material, but in the radioactive waste associated with the non-use and waste reduction and a more effective organization of the Department. (Author)

  8. Mater Nostra: The Anti-blasphemy Message of the Feminist Punk-Prayer

    Directory of Open Access Journals (Sweden)

    Elena Ivanovna Volkova

    2014-12-01

    Full Text Available In this essay I develop a blasphemy counter-discourse arguing that it was ecclesial and state authorities who committed blasphemies, which were condemned by Pussy Riot’s punk-prayer. Thus, the performance in this respect may be interpreted as an anti-blasphemy protest. The blasphemy list includes the collaboration of the church with the authoritarian state, known as heresy of Sergianism; Caesar and Temple idolatry, blasphemy against the Holy Spirit, Virgin Mary and Folly for Christ’s sake. The punk-prayer may be interpreted as a feminine version of the Lord’s Prayer – Mater Nostra. Several corporeal narratives in the background – women’s dress code and rape debates, Virgin Mary’s belt, and its alleged miraculous ability to help women to deliver a baby – may be seen as allegories of feminist vs. patriarchal opposition in Russian religious and political culture.

  9. Sumoylation of Human Translationally Controlled Tumor Protein Is Important for Its Nuclear Transport

    OpenAIRE

    Gnanasekar Munirathinam; Kalyanasundaram Ramaswamy

    2012-01-01

    Translationally controlled tumor protein (TCTP) lacks nuclear bipartite localization signal sequence; yet TCTP is present abundantly in the nucleus. At present it is not known how TCTP gets transported to the nucleus. Sequence analyses showed that all TCTPs described to date have putative small ubiquitin-like modifier (SUMO) motifs. Since SUMO modification plays an important role in the nuclear transport of proteins, we evaluated whether SUMO motifs are important for transport of TCTP into th...

  10. Nuclear Safety Functions of ITER Gas Injection System Instrumentation and Control and the Concept Design

    Science.gov (United States)

    Yang, Yu; Maruyama, S.; Fossen, A.; Villers, F.; Kiss, G.; Zhang, Bo; Li, Bo; Jiang, Tao; Huang, Xiangmei

    2016-08-01

    The ITER Gas Injection System (GIS) plays an important role on fueling, wall conditioning and distribution for plasma operation. Besides that, to support the safety function of ITER, GIS needs to implement three nuclear safety Instrumentation and Control (I&C) functions. In this paper, these three functions are introduced with the emphasis on their latest safety classifications. The nuclear I&C design concept is briefly discussed at the end.

  11. Export Control Guide: Loose Parts Monitoring Systems for Nuclear Power Plants

    Energy Technology Data Exchange (ETDEWEB)

    Langenberg, Donald W. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2012-12-01

    This report describes a typical LPMS, emphasizing its application to the RCS of a modern NPP. The report also examines the versatility of AE monitoring technology by describing several nuclear applications other than loose parts monitoring, as well as some non-nuclear applications. In addition, LPMS implementation requirements are outlined, and LPMS suppliers are identified. Finally, U.S. export controls applicable to LPMSs are discussed.

  12. Near-term improvements for nuclear power plant control room annunciator systems. [PWR; BWR

    Energy Technology Data Exchange (ETDEWEB)

    Rankin, W.L.; Duvernoy, E.G.; Ames, K.R.; Morgenstern, M.H.; Eckenrode, R.J.

    1983-04-01

    This report sets forth a basic design philosophy with its associated functional criteria and design principles for present-day, hard-wired annunciator systems in the control rooms of nuclear power plants. It also presents a variety of annunciator design features that are either necessary for or useful to the implementation of the design philosophy. The information contained in this report is synthesized from an extensive literature review, from inspection and analysis of control room annunciator systems in the nuclear industry and in related industries, and from discussions with a variety of individuals who are knowledgeable about annunciator systems, nuclear plant control rooms, or both. This information should help licensees and license applicants in improving their hard-wired, control room annunciator systems as outlined by NUREG-0700.

  13. El Contrato de Agencia Comercial y los Cambios Introducidos en la Negociación del TLC Entre EE.UU. y los Países Andinos

    Directory of Open Access Journals (Sweden)

    Adriana López

    2011-07-01

    Full Text Available Tomando en consideración que dentro del tratado de libre comercio entre los Países Andinos y los Estados Unidos, se negociaron algunos cambios importantes en la regulación sobre el contrato de agencia comercial, ésta investigación tiene como objetivo principal, mostrar cuales fueron los puntos negociados por los Estados Unidos y por Colombia para este contrato, y exponer cuáles serán los cambios que el Congreso colombiano tendrá que introducir al Código de Comercio, en materia de agencia comercial.

  14. El Contrato de Agencia Comercial y los Cambios Introducidos en la Negociación del TLC Entre EE.UU. y los Países Andinos

    Directory of Open Access Journals (Sweden)

    Adriana López

    2011-06-01

    Full Text Available Tomando en consideración que dentro del tratado de libre comercio entre los Países Andinos y los Estados Unidos, se negociaron algunos cambios importantes en la regulación sobre el contrato de agencia comercial, ésta investigación tiene como objetivo principal, mostrar cuales fueron los puntos negociados por los Estados Unidos y por Colombia para este contrato, y exponer cuáles serán los cambios que el Congreso colombiano tendrá que introducir al Código de Comercio, en materia de agencia comercial.

  15. Development of Export Control Comprehensive Management Model for Nuclear Power Plants and Others Projects

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Chansuh; Seo, Hana; Choi, Sundo [Korea Institute of Nuclear Nonproliferation And Control, Daejeon (Korea, Republic of)

    2014-05-15

    It is required that there are lots of managements of care and concern if the project contains strategic items such as NPPs. The Korean nuclear industry and its related companies, such as the Korea Hydro and Nuclear Power (KHNP), are promoting greater exports of NPPs. It is likely that Korea will export more this technology to newcomer states in the future. As a result, the ROK has been improving its export control management system for NPPs. In keeping with this national effort, Korea Institute of Nuclear Nonproliferation And Control (KINAC) developed comprehensive export control management model for NPPs and other projects, in preparation for this projected growth in the industry. This model also applies to the nuclear export case of the UAE, aims to manage the project from bidding to the end of the contract. The recent Export Licensing of Nuclear Facility Technology was reflected in the Notice on Export and Import of Strategic Items in January 2014. Through this license, the large-scale project legislation framework was established. It can also minimize nonproliferation concerns of the international community through strict management. It is expected that the Korea will be able to enhance transparency and secure the nuclear use, while meeting nonproliferation purpose.

  16. Consideration of Command and Control Performance during Accident Management Process at the Nuclear Power Plant

    Energy Technology Data Exchange (ETDEWEB)

    Ahmed, Nisrene M. [Korea Advanced Institute of Science and Technology, Daejeon (Korea, Republic of); Kim, Sok Chul [Korea Institute of Nuclear Safety, Daejeon (Korea, Republic of)

    2015-10-15

    The accident at the Fukushima Daiichi nuclear power plants shifted the nuclear safety paradigm from risk management to on-site management capability during a severe accident. The kernel of on-site management capability during an accident at a nuclear power plant is situation awareness and agility of command and control. However, little consideration has been given to accident management. After the events of September 11, 2001 and the catastrophic Fukushima nuclear disaster, agility of command and control has emerged as a significant element for effective and efficient accident management, with many studies emphasizing accident management strategies, particularly man-machine interface, which is considered a key role in ensuring nuclear power plant safety during severe accident conditions. This paper proposes a conceptual model for evaluating command and control performance during the accident management process at a nuclear power plant. Communication and information processing while responding to an accident is one of the key issues needed to mitigate the accident. This model will give guidelines for accurate and fast communication response during accident conditions.

  17. Diversity Strategies for Nuclear Power Plant Instrumentation and Control Systems

    Energy Technology Data Exchange (ETDEWEB)

    Wood, Richard Thomas [ORNL; Belles, Randy [ORNL; Cetiner, Mustafa Sacit [ORNL; Holcomb, David Eugene [ORNL; Korsah, Kofi [ORNL; Loebl, Andy [ORNL; Mays, Gary T [ORNL; Muhlheim, Michael David [ORNL; Mullens, James Allen [ORNL; Poore III, Willis P [ORNL; Qualls, A L [ORNL; Wilson, Thomas L [ORNL; Waterman, Michael E. [U.S. Nuclear Regulatory Commission

    2010-02-01

    This report presents the technical basis for establishing acceptable mitigating strategies that resolve diversity and defense-in-depth (D3) assessment findings and conform to U.S. Nuclear Regulatory Commission (NRC) requirements. The research approach employed to establish appropriate diversity strategies involves investigation of available documentation on D3 methods and experience from nuclear power and nonnuclear industries, capture of expert knowledge and lessons learned, determination of best practices, and assessment of the nature of common-cause failures (CCFs) and compensating diversity attributes. The research described in this report does not provide guidance on how to determine the need for diversity in a safety system to mitigate the consequences of potential CCFs. Rather, the scope of this report provides guidance to the staff and nuclear industry after a licensee or applicant has performed a D3 assessment per NUREG/CR-6303 and determined that diversity in a safety system is needed for mitigating the consequences of potential CCFs identified in the evaluation of the safety system design features. Succinctly, the purpose of the research described in this report was to answer the question, 'If diversity is required in a safety system to mitigate the consequences of potential CCFs, how much diversity is enough?' The principal results of this research effort have identified and developed diversity strategies, which consist of combinations of diversity attributes and their associated criteria. Technology, which corresponds to design diversity, is chosen as the principal system characteristic by which diversity criteria are grouped to form strategies. The rationale for this classification framework involves consideration of the profound impact that technology-focused design diversity provides. Consequently, the diversity usage classification scheme involves three families of strategies: (1) different technologies, (2) different approaches within

  18. Sequence variation in the guillemot (Alcidae: Cepphus) mitochondrial control region and its nuclear homolog.

    Science.gov (United States)

    Kidd, M G; Friesen, V L

    1998-01-01

    We describe sequence variation in the mitochondrial control region and its nuclear homolog in three species and seven subspecies of guillemots (Cepphus spp.). Nuclear homologs of the 5' end of the control region were found in all individuals. Nuclear sequences were approximately 50% divergent from their mitochondrial counterparts and formed a distinct phylogenetic clade; the mitochondrial-nuclear introgression event must have predated the radiation of Cepphus. As in other vertebrates, the guillemot control region has a relatively conserved central block flanked by hypervariable 5' and 3' ends. Mean pairwise interspecific divergence values among control regions were lower than those in other birds. All individuals were heteroplasmic for the number of simple tandem nucleotide repeats (A(n)C) at the 3' end of the control region. Phylogenetic analyses suggest that black guillemots are basal to pigeon and spectacled guillemots, but evolutionary relationships among subspecies remain unresolved, possibly due to incomplete lineage sorting. Describing molecular variation in nuclear homologs of mitochondrial genes is of general interest in phylogenetics because, if undetected, the homologs may confound interpretations of mitochondrial phylogenies.

  19. ARMS CONTROL: U.S. Efforts to Control the Transfer of Nuclear-Capable Missile Technology

    Science.gov (United States)

    2015-12-11

    risk of diversion is an important part of its analysis, Commerce focuses its reviews on certain countries that are developing nuclear-capable missiles...ogy to countries developing nuclear-capable missile systems. Our work was conducted in the United States at the Departments of State, Commerce , and...the MTCR in halting the transfer of MTCR-related systems and technology to countries developing nuclear-capable missile systems. The objectives, scope

  20. Nuclear receptors in inflammation control: repression by GR and beyond.

    Science.gov (United States)

    Chinenov, Yurii; Gupte, Rebecca; Rogatsky, Inez

    2013-11-05

    Inflammation is a protective response of organisms to pathogens, irritation or injury. Primary inflammatory sensors activate an array of signaling pathways that ultimately converge upon a few transcription factors such as AP1, NFκB and STATs that in turn stimulate expression of inflammatory genes to ultimately eradicate infection and repair the damage. A disturbed balance between activation and inhibition of inflammatory pathways can set the stage for chronic inflammation which is increasingly recognized as a key pathogenic component of autoimmune, metabolic, cardiovascular and neurodegenerative disorders. Nuclear receptors (NRs) are a large family of transcription factors many of which are known for their potent anti-inflammatory actions. Activated by small lipophilic ligands, NRs interact with a wide range of transcription factors, cofactors and chromatin-modifying enzymes, assembling numerous cell- and tissue-specific DNA-protein transcriptional regulatory complexes with diverse activities. Here we discuss established and emerging roles and mechanisms by which NRs and, in particular, the glucocorticoid receptor (GR) repress genes encoding cytokines, chemokines and other pro-inflammatory mediators.

  1. Review of criteria for nuclear criticality safety control in transportation

    Energy Technology Data Exchange (ETDEWEB)

    Thomas, J. T.; Smith, D. R.

    1978-01-01

    Basic elements in the review of criteria for nuclear criticality safety in transportation are the magnitudes of reactivity changes that may occur to a shipment of packages and those inherent in the regulatory procedure of assessment. The generic representation of criticality of reflected arrays of uncontained fissionable materials is used as a basis for comparison of packaged fissionable materials. The reactivities associated with array changes and perturbations representative of credible conditions that may occur in storage or transportation are summarized for air-spaced units of fissionable materials. Calculations of packaged fissionable material determined reactivities associated with similar changes to arrays of packages. Typical thermal insulating materials being studied are Celotex, wood, Foamglas, and a bonded vermiculite. The effect on the array neutron multiplication of these, with and without steel as an inner and outer container material, is examined. The present stage of the study has produced results illustrating the variable margin of subcriticality manifested by the criteria. Depending upon the packaging, mass loading and array reflector condition, the margin of subcriticality can be of the order of 1% in k/sub eff/.

  2. Muusikapassioon mõttepeeglis. Täna kõlab "Stabat Mater" / Anne Peäske

    Index Scriptorium Estoniae

    Peäske, Anne, 1946-

    2005-01-01

    Arvo Pärdi "Passio" ettekandest 11.sept. Rakvere Kolmainu kirikus. Elmo Lööve, Raivo Palmaru, Jaan Rääts, Toivo Tulev, Aarne Talvik, Ingmar Kurg, Olev Oja ja Eleonora Pärt Arvo Pärdi muusikast. A. Pärdi "Stabat Mater" ansambli Theatre of Voices esituses 14. sept. Rakvere Kolmainu kirikus

  3. The Mater-Bi® biodegradable film for strawberry (Fragaria x ananassa Duch. mulching: effects on fruit yield and quality

    Directory of Open Access Journals (Sweden)

    Luigi Morra

    2016-08-01

    Full Text Available Two trials in different agricultural farms were carried out from October 2014 to June 2015 with the aim to assess the advantages linked to the substitution of the low density polyethylene (LDPE films for soil mulching with the Mater-Bi® biodegradable films in the strawberry cultivation under tunnel in Campania. Lifetime of biodegradable mulch and influence of type of mulch on the yield and the quality of cvs Sabrina and Fortuna were evaluated. Plants were cultivated on mulched, raised beds, high 40 cm from bottom soil. Mater-Bi® film was 20 µm thick while LDPE film was 50 mm thick. The physical-chemical parameters (firmness, pH, total soluble solid content, titratable acidity and skin colour and some bioactive compounds (total polyphenols, flavonoids, anthocyanins, antioxidant activity of fruits were determined by three samplings effected in consecutive months (from March to May 2015 of the harvest cycle. Biodegradable film guaranteed an effective mulch along the whole strawberry cycle (9-10 months including the time of drawing up of film. Yields of cv Sabrina on LDPE was 18% higher than those on Mater-Bi® while the opposite was detected in cv Fortuna (+10%. The physical-chemical parameters of fruits were not modified by the mulches. The content of the bioactive compounds, instead, resulted, in each time of sampling, significantly higher in fruits picked on Mater-Bi® based film.

  4. Nonlinear control for core power of pressurized water nuclear reactors using constant axial offset strategy

    Energy Technology Data Exchange (ETDEWEB)

    Ansarifar, Gholam Reza; Saadatzi, Saeed [Dept. of Nuclear Engineering, Faculty of Advanced Sciences and Technology, University of Isfahan, Isfahan (Iran, Islamic Republic of)

    2015-12-15

    One of the most important operations in nuclear power plants is load following, in which an imbalance of axial power distribution induces xenon oscillations. These oscillations must be maintained within acceptable limits otherwise the nuclear power plant could become unstable. Therefore, bounded xenon oscillation is considered to be a constraint for the load following operation. In this paper, the design of a sliding mode control (SMC), which is a robust nonlinear controller, is presented. SMC is a means to control pressurized water nuclear reactor (PWR) power for the load following operation problem in a way that ensures xenon oscillations are kept bounded within acceptable limits. The proposed controller uses constant axial offset (AO) strategy to ensure xenon oscillations remain bounded. The constant AO is a robust state constraint for the load following problem. The reactor core is simulated based on the two-point nuclear reactor model with a three delayed neutron groups. The stability analysis is given by means of the Lyapunov approach, thus the control system is guaranteed to be stable within a large range. The employed method is easy to implement in practical applications and moreover, the SMC exhibits the desired dynamic properties during the entire output-tracking process independent of perturbations. Simulation results are presented to demonstrate the effectiveness of the proposed controller in terms of performance, robustness, and stability. Results show that the proposed controller for the load following operation is so effective that the xenon oscillations are kept bounded in the given region.

  5. WTEC panel report on European nuclear instrumentation and controls. Final report

    Energy Technology Data Exchange (ETDEWEB)

    White, J.D.; Lanning, D.D.; Johnson, P.M.H. [eds.] [World Technology Evaluation Center, Baltimore, MD (United States); Shelton, R.D. [World Technology Evaluation Center, Baltimore, MD (United States)

    1991-12-01

    A study of instrumentation and controls (I and C) technology used in nuclear power plants in Europe was conducted by a panel of US specialists. This study plants in Europe was conducted by a panel of US specialists. This study included a review of the literature on the subject, followed by a visit to some of the leading organizations in Europe in the field nuclear I and C. Areas covered are: (1) role of the operator and control room design; (2) transition from analog to digital technology; (3) computerized operator support systems for fault management; (4) control strategies and techniques; (5) Nuclear power plant I and C architecture; (6) instrumentation and (7) computer standards and tools. The finding relate to poor reactions.

  6. Technology Roadmap Instrumentation, Control, and Human-Machine Interface to Support DOE Advanced Nuclear Energy Programs

    Energy Technology Data Exchange (ETDEWEB)

    Donald D Dudenhoeffer; Burce P Hallbert

    2007-03-01

    Instrumentation, Controls, and Human-Machine Interface (ICHMI) technologies are essential to ensuring delivery and effective operation of optimized advanced Generation IV (Gen IV) nuclear energy systems. In 1996, the Watts Bar I nuclear power plant in Tennessee was the last U.S. nuclear power plant to go on line. It was, in fact, built based on pre-1990 technology. Since this last U.S. nuclear power plant was designed, there have been major advances in the field of ICHMI systems. Computer technology employed in other industries has advanced dramatically, and computing systems are now replaced every few years as they become functionally obsolete. Functional obsolescence occurs when newer, more functional technology replaces or supersedes an existing technology, even though an existing technology may well be in working order.Although ICHMI architectures are comprised of much of the same technology, they have not been updated nearly as often in the nuclear power industry. For example, some newer Personal Digital Assistants (PDAs) or handheld computers may, in fact, have more functionality than the 1996 computer control system at the Watts Bar I plant. This illustrates the need to transition and upgrade current nuclear power plant ICHMI technologies.

  7. Two-pulse laser control of nuclear and electronic motion

    DEFF Research Database (Denmark)

    Grønager, Michael; Henriksen, Niels Engholm

    1997-01-01

    We discuss an explicitly time-dependent two-pulse laser scheme for controlling where nuclei and electrons are going in unimolecular reactions. We focus on electronic motion and show, with HD+ as an example, that one can find non-stationary states where the electron (with some probability) oscilla...

  8. Temperature-controlled molecular depolarization gates in nuclear magnetic resonance

    Energy Technology Data Exchange (ETDEWEB)

    Schroder, Leif; Schroder, Leif; Chavez, Lana; Meldrum, Tyler; Smith, Monica; Lowery, Thomas J.; E. Wemmer, David; Pines, Alexander

    2008-02-27

    Down the drain: Cryptophane cages in combination with selective radiofrequency spin labeling can be used as molecular 'transpletor' units for transferring depletion of spin polarization from a hyperpolarized 'source' spin ensemble to a 'drain' ensemble. The flow of nuclei through the gate is adjustable by the ambient temperature, thereby enabling controlled consumption of hyperpolarization.

  9. Research on pressure control of pressurizer in pressurized water reactor nuclear power plant

    Science.gov (United States)

    Dai, Ling; Yang, Xuhong; Liu, Gang; Ye, Jianhua; Qian, Hong; Xue, Yang

    2010-07-01

    Pressurizer is one of the most important components in the nuclear reactor system. Its function is to keep the pressure of the primary circuit. It can prevent shutdown of the system from the reactor accident under the normal transient state while keeping the setting value in the normal run-time. This paper is mainly research on the pressure system which is running in the Daya Bay Nuclear Power Plant. A conventional PID controller and a fuzzy controller are designed through analyzing the dynamic characteristics and calculating the transfer function. Then a fuzzy PID controller is designed by analyzing the results of two controllers. The fuzzy PID controller achieves the optimal control system finally.

  10. Multi-region fuzzy logic controller with local PID controllers for U-tube steam generator in nuclear power plant

    Directory of Open Access Journals (Sweden)

    Puchalski Bartosz

    2015-12-01

    Full Text Available In the paper, analysis of multi-region fuzzy logic controller with local PID controllers for steam generator of pressurized water reactor (PWR working in wide range of thermal power changes is presented. The U-tube steam generator has a nonlinear dynamics depending on thermal power transferred from coolant of the primary loop of the PWR plant. Control of water level in the steam generator conducted by a traditional PID controller which is designed for nominal power level of the nuclear reactor operates insufficiently well in wide range of operational conditions, especially at the low thermal power level. Thus the steam generator is often controlled manually by operators. Incorrect water level in the steam generator may lead to accidental shutdown of the nuclear reactor and consequently financial losses. In the paper a comparison of proposed multi region fuzzy logic controller and traditional PID controllers designed only for nominal condition is presented. The gains of the local PID controllers have been derived by solving appropriate optimization tasks with the cost function in a form of integrated squared error (ISE criterion. In both cases, a model of steam generator which is readily available in literature was used for control algorithms synthesis purposes. The proposed multi-region fuzzy logic controller and traditional PID controller were subjected to broad-based simulation tests in rapid prototyping software - Matlab/Simulink. These tests proved the advantage of multi-region fuzzy logic controller with local PID controllers over its traditional counterpart.

  11. Nuclear weapons, scientists, and the post-Cold War challenge selected papers on arms control

    CERN Document Server

    Drell, Sidney D

    2007-01-01

    This volume includes a representative selection of Sidney Drell's recent writings and speeches (circa 1993 to the present) on public policy issues with substantial scientific components. Most of the writings deal with national security, nuclear weapons, and arms control and reflect the author's personal involvement in such issues dating back to 1960. Fifteen years after the demise of the Soviet Union, the gravest danger presented by nuclear weapons is the spread of advanced technology that may result in the proliferation of nuclear weapons. Of most concern would be their acquisition by hostile governments and terrorists who are unconstrained by accepted norms of civilized behavior. The current challenges are to prevent this from happening and, at the same time, to pursue aggressively the opportunity to escape from an outdated nuclear deterrence trap.

  12. Processing used nuclear fuel with nanoscale control of uranium and ultrafiltration

    Science.gov (United States)

    Wylie, Ernest M.; Peruski, Kathryn M.; Prizio, Sarah E.; Bridges, Andrea N. A.; Rudisill, Tracy S.; Hobbs, David T.; Phillip, William A.; Burns, Peter C.

    2016-05-01

    Current separation and purification technologies utilized in the nuclear fuel cycle rely primarily on liquid-liquid extraction and ion-exchange processes. Here, we report a laboratory-scale aqueous process that demonstrates nanoscale control for the recovery of uranium from simulated used nuclear fuel (SIMFUEL). The selective, hydrogen peroxide induced oxidative dissolution of SIMFUEL material results in the rapid assembly of persistent uranyl peroxide nanocluster species that can be separated and recovered at moderate to high yield from other process-soluble constituents using sequestration-assisted ultrafiltration. Implementation of size-selective physical processes like filtration could results in an overall simplification of nuclear fuel cycle technology, improving the environmental consequences of nuclear energy and reducing costs of processing.

  13. FRAMEWORK AND APPLICATION FOR MODELING CONTROL ROOM CREW PERFORMANCE AT NUCLEAR POWER PLANTS

    Energy Technology Data Exchange (ETDEWEB)

    Ronald L Boring; David I Gertman; Tuan Q Tran; Brian F Gore

    2008-09-01

    This paper summarizes an emerging project regarding the utilization of high-fidelity MIDAS simulations for visualizing and modeling control room crew performance at nuclear power plants. The key envisioned uses for MIDAS-based control room simulations are: (i) the estimation of human error associated with advanced control room equipment and configurations, (ii) the investigative determination of contributory cognitive factors for risk significant scenarios involving control room operating crews, and (iii) the certification of reduced staffing levels in advanced control rooms. It is proposed that MIDAS serves as a key component for the effective modeling of cognition, elements of situation awareness, and risk associated with human performance in next generation control rooms.

  14. Pulsed estrogen therapy prevents post-OVX porcine dura mater microvascular network weakening via a PDGF-BB-dependent mechanism.

    Directory of Open Access Journals (Sweden)

    Olga V Glinskii

    Full Text Available In postmenopausal women, estrogen (E2 deficiencies are frequently associated with higher risk of intracranial hemorrhage, increased incidence of stroke, cerebral aneurysm, and decline in cognitive abilities. In younger postpartum women and those using oral contraceptives, perturbations in E2 are associated with higher risk of cerebral venous thrombosis. A number of serious intracranial pathologic conditions linked to E2 deficiencies, such as dural sinus thrombosis, dural fistulae, non-parenchymal intracranial hemorrhages, migraines, and spontaneous cerebrospinal fluid leaks, involve the vessels not of the brain itself, but of the outer fibrous membrane of the brain, the dura mater (DM. The pathogenesis of these disorders remains mysterious and how estrogen regulates structural and functional integrity of DM vasculature is largely unknown. Here, we demonstrate that post ovariectomy (OVX DM vascular remodeling is manifested by microvessel destabilization, capillary rarefaction, increased vascular permeability, and aberrant angio-architecture, and is the result of disrupted E2-regulated PDGF-BB signaling within dura microvasculature. These changes, associated with the reduction in systemic PDGF-BB levels, are not corrected by a flat-dose E2 hormone replacement therapy (HRT, but are largely prevented using HRT schedules mimicking physiological E2 fluctuations. We demonstrate that 1 E2 regulates PDGF-BB production by endothelial cells in a dose-dependent manner and 2 optimization of PDGF-BB levels and induction of robust PDGF-mediated endothelial cell-vascular pericyte interactions require high (estrous E2 concentrations. We conclude that high (estrous levels of E2 are important in controlling PDGF-mediated crosstalk between endothelial cells and pericytes, a fundamental mechanism governing microvessel stability and essential for preserving intracranial homeostasis.

  15. Coherence and control of quantum registers based on electronic spin in a nuclear spin bath.

    Science.gov (United States)

    Cappellaro, P; Jiang, L; Hodges, J S; Lukin, M D

    2009-05-29

    We consider a protocol for the control of few-qubit registers comprising one electronic spin embedded in a nuclear spin bath. We show how to isolate a few proximal nuclear spins from the rest of the bath and use them as building blocks for a potentially scalable quantum information processor. We describe how coherent control techniques based on magnetic resonance methods can be adapted to these solid-state spin systems, to provide not only efficient, high fidelity manipulation but also decoupling from the spin bath. As an example, we analyze feasible performances and practical limitations in the realistic setting of nitrogen-vacancy centers in diamond.

  16. Agencia, materialidad y documentación del arte de los medios

    Directory of Open Access Journals (Sweden)

    Pau Alsina

    2014-07-01

    Full Text Available El arte de los medios goza de una larga y fértil historia que ha generado innumerables prácticas artísticas de gran calidad así como no pocos estudios  teóricos e históricos sobre las diferentes tendencias, creadores, o sobre las diferentes zonas geográficas que han intervenido e intervienen en la construcción de su pasado y su presente (Wilson,2001; Paul, 2003; Daniels, 2004, 2005; Popper, 2007; Grau, 2007; Alsina, 2007; Shanken 2009. No obstante las própias características y el componente experimental inherente a este conjunto de prácticas también ha aportado importantes preguntas relativas a la transformación de la naturaleza de los procesos que el arte de los medios introduce en las formas tradicionales de habérselas con el arte y el mundo del arte. El propósito de este artículo es incidir específicamente en aquellos procesos vinculados a la construcción de archivos y documentación, así como tambien a la propia conservación del arte de los medios, a través de un análisis de la problemática de la materialidad y la agencia en las prácticas artísticas . La perspectiva que adoptaremos no se limitará a la discusión técnica de las diferentes soluciones a las problemáticas planteadas por las mismas prácticas sino más bien a la problematización del problema mismo desde la perspectiva de la arqueología de los medios (Kittler, 1997; Ernst 2005; Zielinski, 2006; Huhtamo, Parikka, 2011; y el conjunto de reflexiones vinculadas al denominado nuevo materialismo (Delanda, 2000; Barad, 2003; Law, 2007; Coole, 2010 . La misma diversidad de taxonomías aparecidas en relación al arte de los medios, en donde a menudo se destaca en la propia terminología su base tecnológica -video arte, net art, software art, a-life art etc..- nos sirve de punto de partida para reivindicar hasta qué punto la agencialidad del substrato  material y tecnológico de la práctica artística está indisolublemente unida a su discurso simb

  17. Proceedings of the second US Department of Energy environmental control symposium. Volume 2. Nuclear energy, conservation, and solar energy

    Energy Technology Data Exchange (ETDEWEB)

    None

    1980-06-01

    These proceedings document the presentations given at the Second Environmental Control Symposium. Symposium presentations highlighted environmental control activities which span the entire DOE. Volume II contains papers relating to: environmental control aspects of nuclear energy use and development; nuclear waste management; renewable energy sources; transportation and building conservation (fuel economy, gasohol, building standards, and industry); and geothermal energy, power transmission, and energy storage. (DMC)

  18. Instrumentation and control developments in the Los Alamos nuclear test program

    Energy Technology Data Exchange (ETDEWEB)

    Perea, J.A.

    1988-01-01

    The United States Department of Energy contracts the Los Alamos National Laboratory to carry out a Nuclear Weapons Test Program in support of the national defense. The program is one of ongoing research to design, build, and test prototype nuclear devices. The goal is to determine what should ultimately be incorporated into the nation's nuclear defense stockpile. All nuclear tests are conducted underground at the Nevada Test Site (NTS). This paper describes the instrumentation and control techniques used by Los Alamos to carry out the tests. Specifically, the contrast between historical methods and new, computer-based technology are discussed. Previous techniques required large numbers of expensive, heavy hardwire cables extending from the surface to the diagnostics rack at the bottom of the vertical shaft. These cables, which provided singular control/monitor functions, have been replaced by a few optical fibers and power cables. This significant savings has been enabled through the adaptation of industrial process control technology using programmable computer control and distributed input/output. Finally, an ongoing process of developing and applying the most suitable instrumentation and control technology to the unique requirements of the Test Program is discussed. 2 refs.

  19. Discussion on software aging management of nuclear power plant safety digital control system.

    Science.gov (United States)

    Liang, Huihui; Gu, Pengfei; Tang, Jianzhong; Chen, Weihua; Gao, Feng

    2016-01-01

    Managing the aging of digital control systems ensures that nuclear power plant systems are in adequate safety margins during their life cycles. Software is a core component in the execution of control logic and differs between digital and analog control systems. The hardware aging management for the digital control system is similar to that for the analog system, which has matured over decades of study. However, software aging management is still in the exploratory stage. Software aging evaluation is critical given the higher reliability and safety requirements of nuclear power plants. To ensure effective inputs for reliability assessment, this paper provides the required software aging information during the life cycle. Moreover, the software aging management scheme for safety digital control system is proposed on the basis of collected aging information.

  20. Las Agencias de Viajes ante la influencia de las Redes Sociales en el turismo. El caso de Ourense.

    Directory of Open Access Journals (Sweden)

    Laura Rodríguez Cid

    2015-01-01

    Full Text Available El modelo turístico tradicional ha experimentado un cambio con la llegada de las nuevas tecnologías. Las tradicionales herramientas de marketing empleadas por las Agencias de Viajes se están quedando atrás para dar paso a nuevos y mejorados métodos de comercialización y promoción de productos turísticos basados en la utilización de las Tecnologías de la Información y la Comunicación (TIC. Los hábitos de compra han cambiado debido a la rápida evolución de Internet en los últimos 10 años. Se ha pasado de la Web 1.0, de carácter estático y de lectura, a la Web 2.0 que ha generalizado la creación de contenidos y la comunicación on -line entre usuarios, convirtiéndose en creadores y a su vez en consumidores de la información. En los últimos años, las empresas turísticas han comenzado a crear canales de comercialización directos con el cliente, evitando así negociar con los intermediarios, lo que ha mejorado la eficiencia y la reducción de costes. Esto ha permitido que los usuarios puedan contratar un viaje o un servicio turístico a través de la red con unos costes notablemente inferiores. El asesoramiento que antes sólo se encontraba en las Agencias de Viajes, ahora es proporcionado por los usuarios que han consumido el servicio y cuya experiencia aporta una visión única y diferente. Todo este fenómeno ha ocasionado que este sector pase a un segundo plano, con un turista más experimentado, más exigente y familiarizado con estas nuevas herramientas nacidas de la Web 2.0. Numerosas agencias han cerrado sus negocios y tienden a desaparecer tal y como las conocemos actualmente. Sin embargo, son muchas las posibilidades que se les presentan si se adaptan al mercado actual, un entorno que fomenta el uso de las nuevas tecnologías y que utiliza la Web 2.0 y las Redes Sociales para mantener y captar nuevos clientes.

  1. Virtual Visit to the ATLAS Control Room by Institute of Nuclear Physics, Cracow, Poland

    CERN Multimedia

    ATLAS Experiment

    2012-01-01

    The 12 Festival of Science "Theory-knowledge-experience...". Fest will be located on the traditional Main Square, which is visited by thousands of citizens and tourists. Institute of Nuclear Physics as usual participates in this annual event. Our visitors will learn the secrets of the CERN experiments on the Large Hadron Collider - ATLAS, LHCb, ALICE, CMS, find out more about the Higgs particles, antimatter quark-gluon plasma (beeing guided by our scientists and PhD students). One of the attractions will be ATLAS Control Room Virtual Visit. Visiting people will have an opportunity to see how ATLAS is controlled and operated to collect its exciting data and ask questions to scientists and engineers involved in LHC program at CERN. Institute of Nuclear Physics has prepared also several interactive demonstrations of Atomic Force Microscopy, Magnetic Resonance, Hadron Therapy and Crystal Physics. The Institute of Nuclear Physics of the Polish Academy of Sciences carries out basic and applied research in physics, ...

  2. Dynamic nuclear polarization and optimal control spatial-selective 13C MRI and MRS

    DEFF Research Database (Denmark)

    Vinding, Mads Sloth; Laustsen, Christoffer; Maximov, Ivan I.

    2013-01-01

    Aimed at 13C metabolic magnetic resonance imaging (MRI) and spectroscopy (MRS) applications, we demonstrate that dynamic nuclear polarization (DNP) may be combined with optimal control 2D spatial selection to simultaneously obtain high sensitivity and well-defined spatial restriction. This is ach......Aimed at 13C metabolic magnetic resonance imaging (MRI) and spectroscopy (MRS) applications, we demonstrate that dynamic nuclear polarization (DNP) may be combined with optimal control 2D spatial selection to simultaneously obtain high sensitivity and well-defined spatial restriction....... This is achieved through the development of spatial-selective single-shot spiral-readout MRI and MRS experiments combined with dynamic nuclear polarization hyperpolarized [1-13C]pyruvate on a 4.7T pre-clinical MR scanner. The method stands out from related techniques by facilitating anatomic shaped region...

  3. Coherent control and suppressed nuclear feedback of a single quantum dot hole qubit

    CERN Document Server

    De Greve, Kristiaan; Press, David; Ladd, Thaddeus D; Bisping, Dirk; Schneider, Christian; Kamp, Martin; Worschech, Lukas; Hoefling, Sven; Forchel, Alfred; Yamamoto, Yoshihisa

    2011-01-01

    Future communication and computation technologies that exploit quantum information require robust and well-isolated qubits. Electron spins in III-V semiconductor quantum dots, while promising candidates, see their dynamics limited by undesirable hysteresis and decohering effects of the nuclear spin bath. Replacing electrons with holes should suppress the hyperfine interaction and consequently eliminate strong nuclear effects. Using picosecond optical pulses, we demonstrate coherent control of a single hole qubit and examine both free-induction and spin-echo decay. In moving from electrons to holes, we observe significantly reduced hyperfine interactions, evidenced by the reemergence of hysteresis-free dynamics, while obtaining similar coherence times, limited by non-nuclear mechanisms. These results demonstrate the potential of optically controlled, quantum dot hole qubits.

  4. Development of design support tool using integrated hierarchical control chart (HCC) and IEC61131 for nuclear power plant control

    Energy Technology Data Exchange (ETDEWEB)

    Nasimi, E.; Gabbar, H.A. [Univ. of Ontario Inst. of Tech., Oshawa, Ontario (Canada)

    2009-07-01

    This paper proposes a new intelligent and highly automated Hierarchical Control Chart (HCC) and operations mapping solution for nuclear power plant operators that provides control system designers, developers and operators with a single view of all elements and systems across a power plant with the integrated interactive data access and information retrieval capabilities that enables a faster fault diagnostics as well aids in a more efficient decision making for the routine daily tasks. (author)

  5. Application of telerobotic control to remote processing of nuclear material

    Energy Technology Data Exchange (ETDEWEB)

    Merrill, R.D.; Grasz, E.L.; Herget, C.J.; Gavel, D.T.; Addis, R.B.; DeMinico, G.A.

    1991-07-08

    In processing radioactive material there are certain steps which have customarily required operators working at glove box enclosures. This can subject the operators to low level radiation dosages and the risk of accidental contamination, as well as generate significant radioactive waste to accommodate the human interaction. An automated system is being developed to replace the operator at the glove box and thus remove the human from these risks, and minimize waste. Although most of the processing can be automated with very little human operator interaction, there are some tasks where intelligent intervention is necessary to adapt to unexpected circumstances and events. These activities will require that the operator be able to interact with the process using a remote manipulator in a manner as natural as if the operator were actually in the work cell. This robot-based remote manipulation system, or telerobot, must provide the operator with an effective means of controlling the robot arm, gripper and tools. This paper describes the effort in progress in Lawrence Livermore National Laboratory to achieve this capability. 8 refs.

  6. 10 CFR 1017.11 - Information exempt from being Unclassified Controlled Nuclear Information.

    Science.gov (United States)

    2010-01-01

    ... scientific information (i.e., information resulting from research directed toward increasing fundamental... 10 Energy 4 2010-01-01 2010-01-01 false Information exempt from being Unclassified Controlled Nuclear Information. 1017.11 Section 1017.11 Energy DEPARTMENT OF ENERGY (GENERAL...

  7. 76 FR 22849 - DoD Unclassified Controlled Nuclear Information (UCNI)

    Science.gov (United States)

    2011-04-25

    ... CONTROLLED NUCLEAR INFORMATION/EXEMPT FROM MANDATORY DISCLOSURE UNDER U.S.C. 552(b)(3), AS AUTHORIZED BY 10 U... any desktop trash or recycling files. (4) Unauthorized disclosure of DoD UCNI justifies investigative.... (1) Pursuant to 10 U.S.C. 128, information that qualifies as DoD UCNI is exempt from...

  8. Synthesis of Model Based Robust Stabilizing Reactor Power Controller for Nuclear Power Plant

    Directory of Open Access Journals (Sweden)

    Arshad Habib Malik

    2011-04-01

    Full Text Available In this paper, a nominal SISO (Single Input Single Output model of PHWR (Pressurized Heavy Water Reactor type nuclear power plant is developed based on normal moderator pump-up rate capturing the moderator level dynamics using system identification technique. As the plant model is not exact, therefore additive and multiplicative uncertainty modeling is required. A robust perturbed plant model is derived based on worst case model capturing slowest moderator pump-up rate dynamics and moderator control valve opening delay. Both nominal and worst case models of PHWR-type nuclear power plant have ARX (An Autoregressive Exogenous structures and the parameters of both models are estimated using recursive LMS (Least Mean Square optimization algorithm. Nominal and worst case discrete plant models are transformed into frequency domain for robust controller design purpose. The closed loop system is configured into two port model form and H? robust controller is synthesized. The H?controller is designed based on singular value loop shaping and desired magnitude of control input. The selection of desired disturbance attenuation factor and size of the largest anticipated multiplicative plant perturbation for loop shaping of H? robust controller form a constrained multi-objective optimization problem. The performance and robustness of the proposed controller is tested under transient condition of a nuclear power plant in Pakistan and found satisfactory.

  9. Advanced international training course on state systems of accounting for and control of nuclear materials

    Energy Technology Data Exchange (ETDEWEB)

    1981-10-01

    This report incorporates all lectures and presentations at the Advanced International Training Course on State Systems of Accounting for and Control of Nuclear Material held April 27 through May 12, 1981 at Santa Fe and Los Alamos, New Mexico, and Richland, Washington, USA. Authorized by the US Nuclear Non-Proliferation Act and sponsored by the US Department of Energy in cooperation with the International Atomic Energy Agency, the course was developed to provide practical training in the design, implementation, and operation of a state system of nuclear materials accountability and control that satisfies both national and international safeguards. Major emphasis for the 1981 course was placed on safeguards methods used at bulk-handling facilities, particularly low-enriched uranium conversion and fuel fabrication plants. The course was conducted by the University of California's Los Alamos National Laboratory, the Battelle Pacific Northwest Laboratory, and Exxon Nuclear Company, Inc. Tours and demonstrations were arranged at both the Los Alamos National Laboratory, Los Alamos, New Mexico, and the Exxon Nuclear fuel fabrication plant, Richland, Washington.

  10. Teoría de agencia: una revisión del origen biológico del delito

    Directory of Open Access Journals (Sweden)

    Iván Araya

    2016-01-01

    Full Text Available Este trabajo aborda la causa del conflicto entre principal y agente, buscando respuestas en las disciplinasde la biología, particularmente en las ciencias de la antropología criminal. Se ha realizado un ensambleentre los hallazgos de la teoría de agencia y la teoría de los delitos de cuello blanco, reinterpretando lasactuaciones del agente desde su configuración entre instinto, herencia y personalidad. Los resultadosen las ciencias biológicas podrían aportar nuevas interpretaciones y explicaciones en las ciencias de laadministración, avanzando hacia mejores conceptualizaciones del conflicto, mediante teorías con mayorcontenido empírico. En general, pese al conflicto permanente entre las partes, su dinámica potencia losresultados perseguidos por el principal.

  11. Modeling and Control of a Large Nuclear Reactor A Three-Time-Scale Approach

    CERN Document Server

    Shimjith, S R; Bandyopadhyay, B

    2013-01-01

    Control analysis and design of large nuclear reactors requires a suitable mathematical model representing the steady state and dynamic behavior of the reactor with reasonable accuracy. This task is, however, quite challenging because of several complex dynamic phenomena existing in a reactor. Quite often, the models developed would be of prohibitively large order, non-linear and of complex structure not readily amenable for control studies. Moreover, the existence of simultaneously occurring dynamic variations at different speeds makes the mathematical model susceptible to numerical ill-conditioning, inhibiting direct application of standard control techniques. This monograph introduces a technique for mathematical modeling of large nuclear reactors in the framework of multi-point kinetics, to obtain a comparatively smaller order model in standard state space form thus overcoming these difficulties. It further brings in innovative methods for controller design for systems exhibiting multi-time-scale property,...

  12. The development of radiation hardened robot for nuclear facility - Development of embedded controller for hydraulic robot

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Byung Kook; Kim, Jae Kwon [Korea Advanced Institute of Science and Technology, Taejon (Korea)

    2000-04-01

    We designed and implemented a reliable hierarchical control system for hydraulic robots for nuclear power plant maintenance. In hazardous environments such as nuclear power plants, robot systems or automated equipment should be used instead of human being for maintenance and repair. Such robot should guarantee high reliability in hazardous environments such as high radiation or high temperature. The overall system is composed of three hierarchical subsystems: i) supervisory controller in safe zone for operator interaction with monitoring and commanding and graphic user interface, ii) master controller in semi-hazardous zone for control function, and iii) slave controller in hazardous zone for sensing and actuation. These subsystems are connected with suitable communication channels: a) master-slave communication channel implemented with CAN (Control Area Network) and b) supervisory-master communication with Ethernet. The master and the slave controllers construct a feedback closed-loop control system. In order to improve reliability, the slave controller is duplicated using cold-standby scheme, and master-slave communication channel is also duplicated. The overall system is implemented harmonically, and we obtained fast control interval of 1msec, which is sufficient for high-performance real-time control. 12 refs., 58 figs., 13 tabs. (Author)

  13. Controlling Halo-chaos Complexity for Nuclear Power System and Managing High Technology Field

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    Variability is one of most important features of complexity in the complex systems because of itssensitivities to small perturbation. Various possible competing behaviors in the systems provide greatflexibility in controlling dynamical complexity and can manage/select a desired behavior for applicationsin real world. In many high-tech fields, how to control or manage complexity is of significant andchallenge issue. Taking as a typical example, accelerator driven clean nuclear power system (ADS) is one

  14. A brief review of intermediate controlled nuclear syntheses (ICNS) without harmful radiations

    Energy Technology Data Exchange (ETDEWEB)

    Lanjewar, R. B. [Department of Chemistry Dharampeth M. P. Deo Memorial Science College, NAGPUR-440033, India rb-lanjewar@rediffmail.com (India)

    2015-03-10

    Hadronic mechanics gave birth to new magnecular fuels. The present day demand is of clean energy source that is cheap and abundant. Clean energy can be obtained by harnessing renewable energy sources like solar, wind etc. Nuclear energy conventionally produced by fission reactions emits hazardous radiation and radioactive waste. The requirements of clean and safe energy gets fulfilled by novel fuel that achieved by elevating the traditional quantum mechanics to hadronic mechanics and to hadronic chemistry. In the present paper, a comprehensive review on both the theoretical and experimental aspect of the Intermediate Controlled Nuclear Synthesis (ICNS) as developed by Italian American Scientist Professor R. M. Santilli.

  15. Simulation of Digital Control Computer of Nuclear Power Plant Based on Virtual Machine Technology

    Energy Technology Data Exchange (ETDEWEB)

    Hou, Xue Yan; Li, Shu; Li, Qing [China Nuclear Power Operation Technology Co., Wuhan (China)

    2011-08-15

    Based on analyzing DCC (Digital Control Computer) instruction sets, memory map, display controllers and I/O system, virtual machine of DCC (abbr. VM DCC) has been developed. The executive and control programs, same as running on NPP (Nuclear Power Plant) unit's DCC, can run on the VM DCC smoothly and get same control results. Dual VM DCC system has been successfully applied in NPP FSS(Full Scope Simulator) training. It not only improves FSS's fidelity but also makes maintaining easier.

  16. Brasil, Argentina e América do Sul

    Directory of Open Access Journals (Sweden)

    Paulo Nogueira Batista Jr.

    2005-12-01

    Full Text Available ESTE trabalho discute alguns aspectos da evolução econômica recente do Brasil, da Argentina e de outros países da América do Sul. Tendências econômicas e intelectuais perigosas, tais como a "globalização", o chamado Consenso de Washington, a dolarização e as negociações da Alca (Área de Livre Comércio das Américas, perderam ímpeto e a América do Sul está se movendo gradualmente na direção de um posicionamento mais independente na condução das suas política econômicas e internacionais. As mudanças foram muito mais significativas na Argentina do que no Brasil e isso se tornou fonte de alguma tensão entre os dois principais países sul-americanos. Não obstante, uma aliança estratégica entre Argentina e Brasil continua sendo a pedra angular da integração da América do Sul.THIS PAPER discusses some aspects of the recent economic evolution of Brazil, Argentina and other South American countries. Dangerous economic and intellectual trends, such as "globalization", the so-called Washington Consensus, dollarization, and FTAA (Free Trade Area of the Americas negotiations, have lost momentum and South America is moving gradually towards a more independent stance in the conduct of its economic and foreign policies. Changes have been much more significant in Argentina than in Brazil and this has become a source of some tension between the two major South American countries. Nevertheless, a strategic alliance between Argentina and Brazil remains the corner stone of South American integration.

  17. Simulation of neutron multiplicity measurements using Geant4. Open source software for nuclear arms control

    Energy Technology Data Exchange (ETDEWEB)

    Kuett, Moritz

    2016-07-07

    Nuclear arms control, including nuclear safeguards and verification technologies for nuclear disarmament typically use software as part of many different technological applications. This thesis proposes to use three open source criteria for such software, allowing users and developers to have free access to a program, have access to the full source code and be able to publish modifications for the program. This proposition is presented and analyzed in detail, together with the description of the development of ''Open Neutron Multiplicity Simulation'', an open source software tool to simulate neutron multiplicity measurements. The description includes physical background of the method, details of the developed program and a comprehensive set of validation calculations.

  18. Regularity of the wear control of radioactive sources from the nuclear measurers; Regularidad del control del desgaste de fuentes radioactivas de los medidores nucleares

    Energy Technology Data Exchange (ETDEWEB)

    Ferreira L, M. [Instituto de Pesquisas Energeticas e Nucleares - IPEN-CNEN-SP, Av. Prof. Lineu Prestes 2242 - Cidade Universitaria -CEP(ZC) 05508-900, tel: (005511) 3816-9215, Sao Paulo, (Brazil)]. e-mail: mflima@ipen.br

    2006-07-01

    The control of radioactive sources in Brazil is regulated by the CNEN (National Comissao of Nuclear Energy). The Laboratory of Descontaminacao of the IPEN (Institute of Energy Y Nuclear Investigations) it offers to the companies that work with nuclear measurers, essays for control of the source wear according to the ISO 9978/1992 through the smear tests Y of leakage. The analyses are taken in alpha Y beta detectors of low bottom radiation with annual detection limits around 1 Bq. Certificates of the accepted analyses by the CNEN for sources that already passed its time of validity assured by the makers, but its continue operational are emitted. The smear test is repeated the whole year, while the leakage test repeats to every two years. A balance of the last two years of the activities of the laboratory shows the regularity of the clients Y the growth of companies specialized in radioprotection with official of radioprotection, credited by the regulatory authority that its act as intermediaries in the process, contacting the clients, gathering the samples next to the proprietors of sources Y hiring our services. Overalls, proves that the inspection activities by part of the regulatory authority are fulfil. In 2004, 192 sources were analyzed by the smear method Y 86 sources by leakage. In 2005, 232 sources were analyzed by the smear method Y 60 sources by leakage. All the leakage tests was made in sources of Americium of oneself Y only client that brings the sources so that they dismantle them to him in the Sources production laboratory of the IPEN. By the quantity Y age of the sources that were analyzed in those two years, it is proven that the number of sources without use conditions (total activity measured by the two added methods smaller than 180Bq) it doesn't arrive to 2%. (Author)

  19. Revision of criteria for foodstuffs control following a nuclear or radiological emergency

    Energy Technology Data Exchange (ETDEWEB)

    Park, Sang Hyun; Lee, Young Min; Jeong, Seung Young [Korea Institute of Nuclear Safety, Daejeon (Korea, Republic of)

    2015-10-15

    GAL(generic action level)s were derived using cost-benefit methods. But the factors used to derive GALs, such as Gross National Product (GNP) and cost of foodstuff, have been changed for last 10 years. Moreover the standards did not consider exposure situation change from emergency exposure to existing exposure situation. In this study, two ways to revise existing standards for foodstuff control were considered; 1st, revision of GAL, 2nd, newly derived reference level. In this study, two methods to revise food control criteria following nuclear emergency were suggested. GAL based on recent GNI and cost of foodstuff would be revised and decreased up to 30 % than existing criteria. DRLs reflecting exposure situation and consumption pattern were smaller than existing criteria for group 1 nuclides. The approach considered in the study would be applied to set up domestic criteria for food control during and following nuclear or radiological emergency.

  20. Analysis results for the stereotypes regarding colors applied to the nuclear power plant control room

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jung Woon; Oh, In Seok; Lee, Yong Hee; Lee, Hyun Chul [KAERI, Taejon (Korea, Republic of); Lee, Dhong Ha [Suwon Univ., Suwon (Korea, Republic of)

    2003-01-01

    The general public not engaged in the nuclear power plant industry have no idea of the color usage in the nuclear control room. So we converted the specific color usage situation into similar but general situations. In questionnaire, we gave subjects the general situation where color coding is applied and alternative colors which were applied to the HF010 guidelines. And we asked the subjects to choose the colors proper to the situation and to rank the colors according to the degree of suitability. Two hundred fifty college students participated in the experiment. The results suggest that we can use any color coding system in the conventional control room and the CRT in the control deck because most people have no special previous color-meaning association but red-emergency relation.

  1. Nuclear EGFR characterize still controlled proliferation retained in better differentiated clear cell RCC.

    Science.gov (United States)

    Ahel, J; Dordevic, G; Markic, D; Mozetic, V; Spanjol, J; Grahovac, B; Stifter, S

    2015-08-01

    Renal cell carcinoma (RCC) is the most common solid kidney tumor representing 2-3% of all cancers, with the highest frequency occurring in Western countries. There was a worldwide and European annual increase in incidence of approximately 2% although incidence has been stabilized in last few years. One third of the patients already have metastases in the time of the diagnosis with poor prognosis because RCC are radio and chemoresistant. The prognostic value of EGFR over-expression in RCC is a controversial issue that could be explained by different histological types of study tumors and non-standardized criteria for evaluation of expression. Recent evidences points to a new mode of EGFR signaling pathway in which activated EGFR undergoes nuclear translocalization and then, as transcription factor, mediates gene expression and other cellular events required for highly proliferating activities. According to our observations, the membranous expression of EGFR associates with high nuclear grade and poor differentiated tumors. On the other hand, nuclear EGFR expression was high in low nuclear graded and well differentiated tumors with good prognosis. We hypothesize that this mode of EGFR signaling characterizes still controlled proliferation retained in well differentiated RCC with Furhman nuclear grade I or II.

  2. Ultrafast control of nuclear spins using only microwave pulses: towards switchable solid-state quantum gates

    CERN Document Server

    Mitrikas, George; Papavassiliou, Georgios

    2009-01-01

    Since the idea of quantum information processing (QIP) fascinated the scientific community, electron and nuclear spins have been regarded as promising candidates for quantum bits (qubits). A fundamental challenge in the realization of a solid-state quantum computer is the construction of fast and reliable two-qubit quantum gates. Of particular interest in this direction are hybrid systems of electron and nuclear spins, where the two qubits are coupled through the hyperfine interaction. However, the significantly different gyromagnetic ratios of electron and nuclear spins do not allow for their coherent manipulation at the same time scale. Here we demonstrate the control of the alpha-proton nuclear spin, I=1/2, coupled to the stable radical CH(COOH)2, S=1/2, in a gamma-irradiated malonic acid single crystal using only microwave pulses. We show that, depending on the state of the electron spin (mS=+1/2 or -1/2), the nuclear spin can be locked in a desired state or oscillate between mI=+1/2 and mI=-1/2 on the na...

  3. Research Status of the Artiifcial Dura Mater%人工硬脑膜材料的研究现状

    Institute of Scientific and Technical Information of China (English)

    张宇杭; 胥光申

    2016-01-01

    在神经外科手术中,硬脑膜替代物对于维持解剖学的完整和脑组织保护是十分重要的。近年来,随着组织工程和生物材料研究技术的发展,人工硬脑膜的研究取得许多进展。本文对人工硬脑膜国内外的相关文献进行了检索和综合分析,并展望了未来人工硬脑膜研究重点和发展方向。%Dura mater substitutes are of great importance in keeping anatomies intact and protecting brain tissue in neurosurgical operations. With the continuous development of tissue engineering and biomaterials in recent years, the research progress of the artiifcial dural materials has made remarkable progress. In this paper, the related literature about dura mater both at home and abroad were searched and analyzed comprehensively. The paper also examined the prospect of the focus and development direction of dura mater in the future research.

  4. Evaluation of quality control of radiopharmaceuticals in Nuclear Medicine service; Avaliacao do controle de qualidade de radiofarmacos em servico de medicina nuclear

    Energy Technology Data Exchange (ETDEWEB)

    Tavares, Jamille A. Lopes; Lira, Renata F. de, E-mail: jam_alt@hotmail.com, E-mail: renatafariasdelira@hotmail.com [Universidade Federal de Pernambuco (UFPE), Recife (Brazil); Santos, Marcus Aurelio P. dos, E-mail: masantos@cnen.gov.br [Centro Regional de Ciencias Nucleares do Nordeste (CRCN-NE/CNEN-PE), Recife, PE (Brazil)

    2014-07-01

    Radiopharmaceuticals are a type of pharmaceutical preparation associated with radionuclides with purpose of diagnosis and therapy. Nuclear Medicine Services (NMS) should perform quality control of radiopharmaceuticals according to the recommendations of the manufacturer and scientific evidences accepted by the National Agency Sanitary Surveillance ( Brazilian ANVISA). This study evaluated the quality of the main radiopharmaceuticals in a NMS of the state of Pernambuco in relation to pH and radiochemical purity. The results showed that 96.8% of the radiopharmaceuticals showed radiochemical purity and all pH values were within the range recommended by the American pharmacopoeia. The study found that the quality control when inserted into the NMS, provides important data that allows exclusion of radiopharmaceuticals with low radiochemistry purity, favoring a reliable diagnosis and ensuring good radiation protection practices and biosecurity for patient and occupationally exposed individuals.

  5. Applying Human Factors Evaluation and Design Guidance to a Nuclear Power Plant Digital Control System

    Energy Technology Data Exchange (ETDEWEB)

    Thomas Ulrich; Ronald Boring; William Phoenix; Emily Dehority; Tim Whiting; Jonathan Morrell; Rhett Backstrom

    2012-08-01

    The United States (U.S.) nuclear industry, like similar process control industries, has moved toward upgrading its control rooms. The upgraded control rooms typically feature digital control system (DCS) displays embedded in the panels. These displays gather information from the system and represent that information on a single display surface. In this manner, the DCS combines many previously separate analog indicators and controls into a single digital display, whereby the operators can toggle between multiple windows to monitor and control different aspects of the plant. The design of the DCS depends on the function of the system it monitors, but revolves around presenting the information most germane to an operator at any point in time. DCSs require a carefully designed human system interface. This report centers on redesigning existing DCS displays for an example chemical volume control system (CVCS) at a U.S. nuclear power plant. The crucial nature of the CVCS, which controls coolant levels and boration in the primary system, requires a thorough human factors evaluation of its supporting DCS. The initial digital controls being developed for the DCSs tend to directly mimic the former analog controls. There are, however, unique operator interactions with a digital vs. analog interface, and the differences have not always been carefully factored in the translation of an analog interface to a replacement DCS. To ensure safety, efficiency, and usability of the emerging DCSs, a human factors usability evaluation was conducted on a CVCS DCS currently being used and refined at an existing U.S. nuclear power plant. Subject matter experts from process control engineering, software development, and human factors evaluated the DCS displays to document potential usability issues and propose design recommendations. The evaluation yielded 167 potential usability issues with the DCS. These issues should not be considered operator performance problems but rather opportunities

  6. Measuring Human Performance in Simulated Nuclear Power Plant Control Rooms Using Eye Tracking

    Energy Technology Data Exchange (ETDEWEB)

    Kovesdi, Casey Robert [Idaho National Lab. (INL), Idaho Falls, ID (United States); Rice, Brandon Charles [Idaho National Lab. (INL), Idaho Falls, ID (United States); Bower, Gordon Ross [Idaho National Lab. (INL), Idaho Falls, ID (United States); Spielman, Zachary Alexander [Idaho National Lab. (INL), Idaho Falls, ID (United States); Hill, Rachael Ann [Idaho National Lab. (INL), Idaho Falls, ID (United States); LeBlanc, Katya Lee [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2015-11-01

    Control room modernization will be an important part of life extension for the existing light water reactor fleet. As part of modernization efforts, personnel will need to gain a full understanding of how control room technologies affect performance of human operators. Recent advances in technology enables the use of eye tracking technology to continuously measure an operator’s eye movement, which correlates with a variety of human performance constructs such as situation awareness and workload. This report describes eye tracking metrics in the context of how they will be used in nuclear power plant control room simulator studies.

  7. Preliminary exploration of the development of a collagenous artificial dura mater for sustained antibiotic release

    Institute of Scientific and Technical Information of China (English)

    WANG Hao; DONG Hui; KANG Cheng-gui; LIN Cheng; YE Xun; ZHAO Yuan-li

    2013-01-01

    Background Intracranial infection is one of the most common complications of open craniocerebral injury and of conventional craniotomy in neurosurgery.The presence of blood-brain barrier leads to lower drug concentrations in the cerebrospinal fluid than in the venous blood.Increasing the intravenous dosage or frequency carries the risk of systemic adverse reactions or infections in other parts of the body.Developing an artificial dura mater (ADM) for sustained antibiotic release for use during neurosurgery can solve the problems perfectly.Methods Three types of drug-loaded ADMs made of collagen and containing cefuroxime sodium,ceftriaxone sodium,or norvancomycin were prepared.The antibacterial activity and sustained release characteristics of the ADMs were examined using bacteriostatic and release tests.Results Single-layered collagen based ADMs (40 mm×50 mm×5 mm) containing 18 mg cefuroxime sodium or ceftriaxone sodium were not suitable for continued development because of drug preservation and stability issues.Using smaller ADMs (20 mm×30 mm×7 mm),containing 4.86 mg of norvancomycin,with increased collagen density and a three-layered film with two outer drug-free films above and below the antibiotic layer resulted in sustained cumulative release of 2.91 mg (59.9%) of norvancomycin over 72 hours.The similar factor (f2) comparison method proved that products from a same batch were statistically significant similar (f2 >50).Conclusions Artificial ADMs made of collagen can be processed to provide a mature dural repair material for the sustained release of norvancomycin.This system may provide a basis for developing sustained release materials for other drugs.

  8. Anthropometric Considerations in the Modernized Main Control Room: Application to a Virtual Nuclear Power Plant Control Panel

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Chih Wei; Cheng, Tsung Chieh [Institute of Nuclear Energy Research, Taoyuan (China); Lin, Chiuhsiang Joe [Chung-Yuan Christian University, Chung Li (China)

    2011-08-15

    This study investigates the anthropometric considerations in the main control room (MCR) application to a virtual nuclear power plant (NPP) control panel. Influences of working postures and physical demands on the operational performance are also discussed. Finally, the present research provides a case example to illustrate the influences of anthropometric considerations on the control panel design for MCR operators by applying virtual reality (VR) technology. The MCR design primarily evolved in different countries. The datasets available is usually insufficient or inconsistent for the end users. To solve the upper mentioned problem, this study put emphasis on applying VR technology to anthropometric considerations support control panel design in the modernized MCR. Although the concept of applying VR technology on anthropometric considerations in this paper is related to the MCR in NPPs, it could be easily applied for the purposes of any type of control room in a similar manner.

  9. Development of nuclear power plant online monitoring system using statistical quality control

    Energy Technology Data Exchange (ETDEWEB)

    An, Sang Ha

    2006-02-15

    Statistical Quality Control techniques have been applied to many aspects of industrial engineering. An application to nuclear power plant maintenance and control is also presented that can greatly improve plant safety. As a demonstration of such an approach, a specific system is analyzed: the reactor coolant pumps (RCP) and the fouling resistance of heat exchanger. This research uses Shewart X-bar, R charts, Cumulative Sum charts (CUSUM), and Sequential Probability Ratio Test (SPRT) to analyze the process for the state of statistical control. And we made Control Chart Analyzer (CCA) to support these analyses that can make a decision of error in process. The analysis shows that statistical process control methods can be applied as an early warning system capable of identifying significant equipment problems well in advance of traditional control room alarm indicators. Such a system would provide operators with enough time to respond to possible emergency situations and thus improve plant safety and reliability.

  10. Reflected kinetics model for nuclear space reactor kinetics and control scoping calculations

    Energy Technology Data Exchange (ETDEWEB)

    Washington, K.E.

    1986-05-01

    The objective of this research is to develop a model that offers an alternative to the point kinetics (PK) modelling approach in the analysis of space reactor kinetics and control studies. Modelling effort will focus on the explicit treatment of control drums as reactivity input devices so that the transition to automatic control can be smoothly done. The proposed model is developed for the specific integration of automatic control and the solution of the servo mechanism problem. The integration of the kinetics model with an automatic controller will provide a useful tool for performing space reactor scoping studies for different designs and configurations. Such a tool should prove to be invaluable in the design phase of a space nuclear system from the point of view of kinetics and control limitations.

  11. RanBP3 Regulates Melanoma Cell Proliferation via Selective Control of Nuclear Export.

    Science.gov (United States)

    Pathria, Gaurav; Garg, Bhavuk; Wagner, Christine; Garg, Kanika; Gschaider, Melanie; Jalili, Ahmad; Wagner, Stephan N

    2016-01-01

    Chromosome region maintenance 1-mediated nucleocytoplasmic transport has been shown as a potential anticancer target in various malignancies. However, the role of the most characterized chromosome region maintenance 1 cofactor ran binding protein 3 (RanBP3) in cancer cell biology has never been investigated. Utilizing a loss-of-function experimental setting in a vast collection of genetically varied melanoma cell lines, we observed the requirement of RanBP3 in melanoma cell proliferation and survival. Mechanistically, we suggest the reinstatement of transforming growth factor-β (TGF-β)-Smad2/3-p21(Cip1) tumor-suppressor axis as part of the RanBP3 silencing-associated antiproliferative program. Employing extensive nuclear export sequence analyses and immunofluorescence-based protein localization studies, we further present evidence suggesting the requirement of RanBP3 function for the nuclear exit of the weak nuclear export sequence-harboring extracellular signal-regulated kinase protein, although it is dispensable for general CRM1-mediated nuclear export of strong nuclear export sequence-harboring cargoes. Rendering mechanistic support to RanBP3 silencing-mediated apoptosis, consequent to extracellular signal-regulated kinase nuclear entrapment, we observed increased levels of cytoplasmically restricted nonphosphorylated/active proapoptotic Bcl-2-antagonist of cell death (BAD) protein. Last, we present evidence suggesting the frequently activated mitogen-activated protein kinase signaling in melanoma as a potential founding basis for a deregulated post-translational control of RanBP3 activity. Collectively, the presented data suggest RanBP3 as a potential target for therapeutic intervention in human melanoma.

  12. The potential role of nuclear power in controlling CO sub 2 emissions

    Energy Technology Data Exchange (ETDEWEB)

    Fulkerson, W.; Jones, J.E.; Delene, J.G.; Perry, A.M.; Cantor, R.A.

    1990-01-01

    Nuclear power currently reduces CO{sub 2} emissions from fossil fuel burning worldwide by about 8% (0.4 Gt(C)/yr). It can continue to play an important role only if it can grow substantially in the next 50 years. For such growth to occur public confidence will need to improve throughout the world. That might happen if (a) other non-fossil alternatives are inadequate to meet electricity demand growth, (b) the risks to society from global warming are perceived to be very high, (c) nuclear technology improves substantially, and (d) an international institutional setting is devised to manage the nuclear enterprise so that the technology is available to all nations while catastrophic accidents and proliferation of nuclear weapon capabilities are avoided. It seems feasible that the necessary technological and institutional advances can be devised and tested over the next 20 years. It is also plausible that the direct costs of electricity produced by the system would be in the range of 50-100 mills/kWhr (1990 dollars) delivered to the grid. In other words, the direct costs of nuclear power should not be greater than they are today. Achieving such an outcome will require aggressive technical and institutional RD D performed in a cooperative international setting. If rapid growth of nuclear power can begin again in 15-20 years it could supply 30-50% of world electricity in 50 years and cut CO{sub 2} emission rates by up to 2.5 Gt(C)/yr. This would be a substantial contribution to controlling greenhouse gases, but it is not sufficient. Improved efficiency and various renewable energy sources must also grow rapidly if CO{sub 2} emission rates from electricity generation are to be reduced from the current value of about 2 Gt(C)/yr. 41 refs., 4 figs., 3 tabs.

  13. INDUSTRIAL CONTROL SYSTEM CYBER SECURITY: QUESTIONS AND ANSWERS RELEVANT TO NUCLEAR FACILITIES, SAFEGUARDS AND SECURITY

    Energy Technology Data Exchange (ETDEWEB)

    Robert S. Anderson; Mark Schanfein; Trond Bjornard; Paul Moskowitz

    2011-07-01

    Typical questions surrounding industrial control system (ICS) cyber security always lead back to: What could a cyber attack do to my system(s) and; how much should I worry about it? These two leading questions represent only a fraction of questions asked when discussing cyber security as it applies to any program, company, business, or organization. The intent of this paper is to open a dialog of important pertinent questions and answers that managers of nuclear facilities engaged in nuclear facility security and safeguards should examine, i.e., what questions should be asked; and how do the answers affect an organization's ability to effectively safeguard and secure nuclear material. When a cyber intrusion is reported, what does that mean? Can an intrusion be detected or go un-noticed? Are nuclear security or safeguards systems potentially vulnerable? What about the digital systems employed in process monitoring, and international safeguards? Organizations expend considerable efforts to ensure that their facilities can maintain continuity of operations against physical threats. However, cyber threats particularly on ICSs may not be well known or understood, and often do not receive adequate attention. With the disclosure of the Stuxnet virus that has recently attacked nuclear infrastructure, many organizations have recognized the need for an urgent interest in cyber attacks and defenses against them. Several questions arise including discussions about the insider threat, adequate cyber protections, program readiness, encryption, and many more. These questions, among others, are discussed so as to raise the awareness and shed light on ways to protect nuclear facilities and materials against such attacks.

  14. Personnel exposure control system with auto thermoluminescence dosimeter in Shimane Nuclear Power Station

    Energy Technology Data Exchange (ETDEWEB)

    Matsubayashi, Hideo; Ochi, Susumu (Chugoku Electric Power Co. Inc., Hiroshima (Japan))

    1982-03-01

    In the past, film badges and pocket dosimeters were put on the persons who entered a controlled area in a nuclear power station to measure the external radiation exposure. For these, read out error or mistake, delay in taking out the result, trouble for monitoring many persons, etc. were problems. To solve these problems, the auto thermoluminescence dosimeter (ATLD) system has been introduced in Shimane Nuclear Power Station in place of pocket dosimeters since the second half of fiscal 1978. The outline of the system and the composition and software of the TLD automatic readout system are described. For the control of access to controlled areas, workers are forced to pass the check point where watchmen check everyone's ID card, and subjected to the check-up with the TLD automatic readout device. The checking items in the case of entering the areas are: (1) confirmation of licensee, (2) confirmation of the term of validity for the medical examination on ionizing radiation, (3) checking for exposure dose compared to the controlled exposure level, (4) confirmation of time limit to stay in controlled areas, and (5) TLD element annealing condition. The checking items in the case of leaving the areas are: (1) checking for identifying the TLD element that the personnel has brought in, (2) exposure dose compared to the controlled exposure level, (3) time for which the personnel stayed in controlled areas.

  15. Nonlinear Adaptive Dynamic Output-Feedback Power-Level Control of Nuclear Heating Reactors

    Directory of Open Access Journals (Sweden)

    Zhe Dong

    2013-01-01

    Full Text Available Due to the high safety performance of small nuclear reactors, there is a promising future for small reactors. Nuclear heating reactor (NHR is a small reactor that has many advanced safety features such as the integrated arrangement, natural circulation at any power levels, self-pressurization, hydraulic control rod driving, and passive residual heating removing and can be applied to the fields of district heating, seawater desalination, and electricity production. Since the NHR dynamics has strong nonlinearity and uncertainty, it is meaningful to develop the nonlinear adaptive power-level control technique. From the idea of physically based control design method, a novel nonlinear adaptive power-level control is given for the NHR in this paper. It is theoretically proved that this newly built controller does not only provide globally asymptotic closed-loop stability but is also adaptive to the system uncertainty. Numerical simulation results show the feasibility of this controller and the relationship between the performance and controller parameters.

  16. Baseline Evaluations to Support Control Room Modernization at Nuclear Power Plants

    Energy Technology Data Exchange (ETDEWEB)

    Boring, Ronald L.; Joe, Jeffrey C.

    2015-02-01

    For any major control room modernization activity at a commercial nuclear power plant (NPP) in the U.S., a utility should carefully follow the four phases prescribed by the U.S. Nuclear Regulatory Commission in NUREG-0711, Human Factors Engineering Program Review Model. These four phases include Planning and Analysis, Design, Verification and Validation, and Implementation and Operation. While NUREG-0711 is a useful guideline, it is written primarily from the perspective of regulatory review, and it therefore does not provide a nuanced account of many of the steps the utility might undertake as part of control room modernization. The guideline is largely summative—intended to catalog final products—rather than formative—intended to guide the overall modernization process. In this paper, we highlight two crucial formative sub-elements of the Planning and Analysis phase specific to control room modernization that are not covered in NUREG-0711. These two sub-elements are the usability and ergonomics baseline evaluations. A baseline evaluation entails evaluating the system as-built and currently in use. The usability baseline evaluation provides key insights into operator performance using the control system currently in place. The ergonomics baseline evaluation identifies possible deficiencies in the physical configuration of the control system. Both baseline evaluations feed into the design of the replacement system and subsequent summative benchmarking activities that help ensure that control room modernization represents a successful evolution of the control system.

  17. Reliable Wireless Data Acquisition and Control Techniques within Nuclear Hot Cell Facilities

    Energy Technology Data Exchange (ETDEWEB)

    Kurtz, J.L.; Tulenko, J.

    2000-09-20

    On this NEER project the University of Florida has investigated and applied advanced communications techniques to address data acquisition and control problems within the Fuel Conditioning Facility (FCF) of Argonne National Laboratory-West (ANL-W) in Idaho Falls. The goals of this project have been to investigate and apply wireless communications techniques to solve the problem of communicating with and controlling equipment and systems within a nuclear hot cell facility with its attendant high radiation levels. Different wireless techniques, including radio frequency, infrared and power line communications were reviewed. For each technique, the challenges of radiation-hardened implementation were addressed. In addition, it has been a project goal to achieve the highest level of system reliability to ensure safe nuclear operations. Achievement of these goals would allow the eventual elimination of through-the-wall, hardwired cabling that is currently employed in the hot cell, along wit h all of the attendant problems that limit measurement mobility and flexibility.

  18. Production of an English/Russian glossary of terminology for nuclear materials control and accounting

    Energy Technology Data Exchange (ETDEWEB)

    Schachowskoj, S.; Smith, H.A. Jr.

    1995-05-01

    The program plans for Former Soviet Union National Nuclear Materials Control and Accounting (MC and A) Systems Enhancements call for the development of an English/Russian Glossary of MC and A terminology. This glossary was envisioned as an outgrowth of the many interactions, training sessions, and other talking and writing exercises that would transpire in the course of carrying out these programs. This report summarizes the status of the production of this glossary, the most recent copy of which is attached to this report. The glossary contains over 950 terms and acronyms associated with nuclear material control and accounting for safeguards and nonproliferation. This document is organized as follows: English/Russian glossary of terms and acronyms; Russian/English glossary of terms and acronyms; English/Russian glossary of acronyms; and Russian/English glossary of acronyms.

  19. Quality control in nuclear fuel fabrication on the inspection basis; Control de calidad para fabricacion de combustible nuclear en base a inspecciones

    Energy Technology Data Exchange (ETDEWEB)

    Fuentes S, A. [Instituto Tecnologico de Toluca, Toluca (Mexico)

    1997-12-31

    Every plant productive of electric power requires the use of energetics for the transformation to electricity. In the nucleo electric plant the energetic is the uranium, in which it makes ensembles and is used as fuel in the reactor. To assure that the fuel ensembles fulfill the specifications and requirements of design stipulated in the nucleo electric plant is that under a quality control through inspections during the fabrication process. The purpose of this work is to study and verify that the lineaments of the standard 10 CFR 50 appendix B `Quality assurement for nuclear plants` specially in the criteria `Inspections` that is used to guarantee the quality of the ensembles. This standard is the one that rules every activity and operation inside the pilot plant and its established in the quality program in the production of nuclear fuel for the Laguna Verde plant. The quality of the assemble is verified through each one of the tests or inspections due to the importance of it in the fabrication of fuel. (Author)

  20. Idiopathic spinal cord herniation with duplicated dura mater and dorsal subarachnoid septum. Report of a case and review of the literature

    Science.gov (United States)

    Yamamoto, Norio; Higashino, Kousaku; Sairyo, Koichi

    2014-01-01

    Background Idiopathic spinal cord herniation (ISCH) is a rare condition and its pathogenesis remains unclear. The purpose of this case report is to present an ISCH case with dorsal subarachnoid septum suggesting the pathogenesis of ISCH being adhesions from preexisting inflammation. Methods Single case report. Results A 60-year-old woman presented with Brown-Séquard syndrome below the level of T6. Magnetic resonance imaging revealed the thoracic spinal cord was displaced ventrally, and the dorsal subarachnoid space was enlarged and had a septum between the spinal cord and dura mater. Intraoperatively, the dorsal dura mater was seen to be adherent and the subarachnoid septum was identified after durotomy. The inner layer defect of the duplicated dura mater was found in the ventral dura mater, through which the spinal cord had herniated. After releasing the septum, the adhesions around the dura mater, and the hiatus, the spinal cord was reduced. Conclusions The present case indicates that adhesions around the dura mater can be the pathogenesis of ISCH. PMID:25694934

  1. Logical operations with single x-ray photons via dynamically-controlled nuclear resonances.

    Science.gov (United States)

    Gunst, Jonas; Keitel, Christoph H; Pálffy, Adriana

    2016-04-27

    Photonic qubits lie at the heart of quantum information technology, often encoding information in their polarization state. So far, only low-frequency optical and infrared photons have been employed as flying qubits, as the resources that are at present easiest to control. With their essentially different way of interacting with matter, x-ray qubits would bear however relevant advantages: they are extremely robust, penetrate deep through materials, and can be focused down to few-nm waveguides, allowing unprecedented miniaturization. Also, x-rays are resonant to nuclear transitions, which are very well isolated from the environment and present long coherence times. Here, we show theoretically that x-ray polarization qubits can be dynamically controlled by nuclear Mössbauer resonances. The control knob is played by nuclear hyperfine magnetic fields, that allow via fast rotations precise processing of single x-ray quanta polarization. With such rotations, single-qubit and binary logical operations such as a destructive C-NOT gate can be implemented.

  2. NaK flow control by electromagnetic pump of the SNAP-10A space nuclear reactor

    Energy Technology Data Exchange (ETDEWEB)

    Borges, Eduardo M.; Braz Filho, Francisco A.; Guimaraes, Lamartine N.F., E-mail: eduardo@ieav.cta.br, E-mail: fbraz@ieav.cta.br, E-mail: guimarae@ieav.cta.br [Instituto de Estudos Avancados (IEAv/DCTA), Sao Jose dos Campos, SP (Brazil)

    2013-07-01

    In the Institute for Advanced Studies (IEAv), were developed, successfully, the first two direct current electromagnetic pumps (DC EM pumps) of Brazil. The first was built with C-type magnet and coils; and the second, with Samarium-Cobalt permanent magnets, for magnetic field generation. Both were tested and performed quite satisfactory. The electromagnetic pump uses the Faraday principle, in which the interaction of the magnetic field and electric current generates the magneto-motive force, which produces the circulation of the fluid. This type of equipment may be used for controlling the liquid metal flow in nuclear space fast reactors. This paper shows the computer programs developed for design and evaluation of DC EM and electromagnetic thermoelectric (EMTE) pumps, the DC EM pump of Samarium-Cobalt magnets data to Mercury loop flow control, the EMTE pump of SNAP space nuclear reactor. It also compares the theoretical results to experimental data of NaK primary loop flow control by electromagnetic thermoelectric pump of the SNAP-10A space nuclear reactor, with satisfactory results, confirming the viability of the electromagnetic pumps evaluation scheme. (author)

  3. Los archivos fotográficos de las agencias como fuentes de información para las televisiones españolas

    Directory of Open Access Journals (Sweden)

    Caldera-Serrano, Jorge

    2015-02-01

    Full Text Available Se describe el uso del material fotográfico en los sistemas de información documental de las empresas audiovisuales televisivas, centrándonos posteriormente en las agencias de información como fuente de información primaria en dichas instituciones. Para realizar este análisis, se describen igualmente los sistemas documentales de las cadenas así como el uso actual de material fotográfico en las empresas audiovisuales. Se descubre el escaso uso de material fotográfico en las empresas televisivas y la cada vez menor existencia de departamentos de documentación fotográfica en las televisiones, siendo sustituido por la adquisición de material fotográfico a agencias de noticias.

  4. Sumoylation of Human Translationally Controlled Tumor Protein Is Important for Its Nuclear Transport

    Directory of Open Access Journals (Sweden)

    Gnanasekar Munirathinam

    2012-01-01

    Full Text Available Translationally controlled tumor protein (TCTP lacks nuclear bipartite localization signal sequence; yet TCTP is present abundantly in the nucleus. At present it is not known how TCTP gets transported to the nucleus. Sequence analyses showed that all TCTPs described to date have putative small ubiquitin-like modifier (SUMO motifs. Since SUMO modification plays an important role in the nuclear transport of proteins, we evaluated whether SUMO motifs are important for transport of TCTP into the nucleus. We show that TCTP exists in sumoylated form in cytoplasm and nucleus of mammalian cells. Point mutation of lysine residue in the SUMO motif compromised the ability of TCTP to get sumoylated in vitro. When cells were transfected with FLAG-tagged mutated TCTP, nuclear transport of TCTP was inhibited confirming that sumoylation is critical for the nuclear transport of TCTP. Our previous studies demonstrated that TCTP can function as an antioxidant protein in the nucleus. When we mutated TCTP at the SUMO motif the antioxidant function of TCTP was compromised. Results presented in this study thus show that sumoylation plays an important role in the transport of TCTP into the nucleus where they function as antioxidant protein.

  5. Prioridades de intervención para la fase aguda de las emergencias complejas formuladas por nueve agencias de ayuda humanitaria

    OpenAIRE

    2004-01-01

    Las Emergencias Complejas son un problema de Salud Pública internacional de frecuencia y magnitud crecientes que producen una importante mortalidad y morbilidad especialmente durante su fase aguda. El objetivo de este estudio es identificar y analizar las áreas prioritarias de intervención en la fase aguda de una emergencia compleja formuladas en los manuales operativos de las principales agencias de ayuda, así como el nivel de desarrollo y estructuración de las actividad...

  6. Dynamic flowgraph modeling of process and control systems of a nuclear-based hydrogen production plant

    Energy Technology Data Exchange (ETDEWEB)

    Al-Dabbagh, Ahmad W. [Faculty of Engineering and Applied Science, University of Ontario Institute of Technology, 2000 Simcoe Street North, Oshawa, Ontario (Canada); Lu, Lixuan [Faculty of Energy Systems and Nuclear Science, Faculty of Engineering and Applied Science, University of Ontario Institute of Technology, 2000 Simcoe Street North, Oshawa, Ontario (Canada)

    2010-09-15

    Modeling and analysis of system reliability facilitate the identification of areas of potential improvement. The Dynamic Flowgraph Methodology (DFM) is an emerging discrete modeling framework that allows for capturing time dependent behaviour, switching logic and multi-state representation of system components. The objective of this research is to demonstrate the process of dynamic flowgraph modeling of a nuclear-based hydrogen production plant with the copper-chlorine (Cu-Cl) cycle. Modeling of the thermochemical process of the Cu-Cl cycle in conjunction with a networked control system proposed for monitoring and control of the process is provided. This forms the basis for future component selection. (author)

  7. Material control and accounting in the Department of Energy's nuclear fuel complex

    Energy Technology Data Exchange (ETDEWEB)

    None

    1989-01-01

    Material control and accounting takes place within an envelope of activities related to safeguards and security, as well as to safety, health, and environment, all of which need to be managed to assure that the entire nuclear fuel complex can operate in a societally accepted manner. Within this envelope the committee was directed to carry out the following scope of work: (1) Review the MCandA systems in use at selected DOE facilities that are processing special nuclear material (SNM) in various physical and chemical forms. (2) Design and convene a workshop for senior representatives from each of DOE's facilities on the flows and inventories of nuclear materials. (3) Plan and conduct a series of site visits to each of the facilities to observe first hand the processing operations and the related MCandA systems. (4) Review the potential improvement in overall safeguard systems effectiveness, as measured by expected reduction in inventory difference control limits and inventory differences for materials balance accounts and facilities, or other criteria as appropriate. Indicate how this affects the relative degree of uncertainty in the system. (5) Review the efficiency of operating the MCandA system with and without the upgrading options and assess whether upgrading will contribute further efficiencies in operation, which may reduce many of the current operations costs. Determine if the current system is cost-effective. (6) Recommend the most promising technical approaches for further development by DOE and further study as warranted.

  8. Emergency control room design of a nuclear reactor used to produce radioisotope

    Energy Technology Data Exchange (ETDEWEB)

    Santos, Isaac J.A.L. dos; Farias, Larissa P. de; Ponte, Luana T.L.; Goncalves, Gabriel L.; Castro, Heraclito M.; Farias, Marcos S.; Carvalho, Paulo V.R. de; Vianna Filho, Alfredo M.V., E-mail: luquetti@ien.gov.br [Instituto Engenharia Nuclear (IEN/CNEN-RJ), Rio de Janeiro, RJ (Brazil). Departamento Engenharia Nuclear

    2015-07-01

    A control room is defined as a functional entity with an associated physical structure, where the operators carry out the centralized control, monitoring and administrative responsibilities. Emergency control room acts as an alternative control room for the purpose of shutting down or maintaining the facility in a safe shutdown state when the main control room is uninhabitable. The mission of emergency control room is to provide the resources to bring the plant to a safe shutdown condition after an evacuation of the main control room. An evacuation of the main control room is assumed when there is no possibility to accomplish tasks involved in the shutdown except reactor trip. The purpose of this paper is to present a specific approach for the design of the emergency control room of a nuclear reactor used to produce radioisotope. The approach is based on human factors standards and the participation of a multidisciplinary team in the development phase of the design. Using the information gathered from standards and from the multidisciplinary team a 3D Sketch and a 3D printing of the emergency control room were created. (author)

  9. Identificação e diferenciação de herpesvírus bovino tipos 1 e 5 isolados de amostras clínicas no Centro-Sul do Brasil, Argentina e Uruguai (1987-2006 Identification and differentiation of herpesvirus types 1 and 5 isolated from clinical samples in central-southern Brazil, Argentina and Uruguay (1987-2006

    Directory of Open Access Journals (Sweden)

    Mariana Sá e Silva

    2007-10-01

    Full Text Available Os herpesvírus bovino tipos 1 e 5 (BoHV-1; BoHV-5 são genética e antigenicamente muito semelhantes e por isso são indistinguíveis pela maioria dos testes diagnósticos. Como o BoHV-1 tem sido classicamente associado com doença respiratória e genital, os herpesvírus isolados dessas enfermidades têm sido provisoriamente - e às vezes definitivamente - identificados como BoHV-1. Da mesma forma, os casos de infecção neurológica por herpesvírus em bovinos têm sido atribuídos em sua totalidade ao BoHV-5. Este trabalho relata a identificação de 40 amostras de herpesvírus isoladas de diferentes casos clínicos na região Centro-Sul do Brasil, Argentina e Uruguai entre 1987 e 2006, pelo uso de um PCR capaz de diferenciar esses vírus. As amostras identificadas como BoHV-1 (n=16 foram isoladas de doença respiratória (n=3, balanopostite e/ou vulvovaginite (n=3, do sêmen de touros saudáveis (n=5 e de casos doença neurológica (n=5. As amostras virais identificadas como BoHV-5 (n=24 foram em sua maioria isoladas de doença neurológica (n=21, mas também do sêmen de touros saudáveis (n=2 e do baço de um bezerro com doença sistêmica (n=1. Esses resultados demonstram que tanto o BoHV-1 como o BoHV-5 não estão estritamente associados às suas respectivas síndromes clínicas e que podem estar freqüentemente envolvidos em casos clínicos classicamente atribuídos ao outro vírus. Esses achados também reforçam a necessidade de se identificar corretamente os isolados de herpesvírus para um melhor conhecimento da sua patogenia e epidemiologia.Bovine herpesviruses types 1 and 5 (BoHV-1; BoHV-5 are genetically and antigenically closely related such they can not be distinguished by routine diagnostic tests. As BoHV-1 has been historically associated with respiratory and genital disease, herpesviruses isolated from these clinical syndromes have been tentatively - and sometimes definitively - diagnosed as BoHV-1. Likewise, cases of

  10. Radiation exposure control from the application of nuclear gauges in the mining industry in Ghana.

    Science.gov (United States)

    Faanu, A; Darko, E O; Awudu, A R; Schandorf, C; Emi-Reynolds, G; Yeboah, J; Glover, E T; Kattah, V K

    2010-05-01

    The use of nuclear gauges for process control and elemental analysis in the mining industry in Ghana, West Africa, is wide spread and on the increase in recent times. The Ghana Radiation Protection Board regulates nuclear gauges through a system of notification and authorization by registration or licensing, inspection, and enforcement. Safety assessments for authorization and enforcement have been established to ensure the safety and security of radiation sources as well as protection of workers and the general public. Appropriate training of mine staff is part of the efforts to develop the necessary awareness about the safety and security of radiation sources. The knowledge and skills acquired will ensure the required protection and safety at the workplaces. Doses received by workers monitored over a period between 1998 and 2007 are well below the annual dose limit of 20 mSv recommended by the International Commission on Radiological Protection.

  11. Emerging Technologioes in Instrumentation and Controls and Their Potential Regulatory Implications for Nuclear Power Plants

    Energy Technology Data Exchange (ETDEWEB)

    Korsah, Kofi [ORNL; Bobrek, Miljko [ORNL; Cetiner, Mustafa Sacit [ORNL; Ewing, Paul D [ORNL; Holcomb, David Eugene [ORNL; Howlader, Mostofa [ORNL; Killough, Stephen M [ORNL; Kisner, Roger A [ORNL; Loebl, Andy [ORNL; Moore, Michael Roy [ORNL; Muhlheim, Michael David [ORNL; Mullens, James Allen [ORNL; Shourbaji, Ayman A [ORNL; Wilson, Thomas L [ORNL

    2009-01-01

    This paper provides a summary of eight instrumentation and control (&C) technology areas, with applications in nuclear power plants (NPPs), that were the focus of a recent study performed by Oak Ridge National Laboratory (ORNL) for the Nuclear Regulatory Commission (NRC.) The state of the technology s application in NPPs, along with potential regulatory impact(s), are discussed. The technology focus areas are: (1) sensors and measurement systems, (2) communications media and networking, (3) microprocessors and other integrated circuits, (4) computational platforms, (5) surveillance, diagnostics, and prognostics, (6) human-system interactions, (7) high-integrity software, and (8) I&C architectures in new plants. The regulatory implications of these focus areas with regard to their application in NPPs are also discussed.

  12. Review of Methods Related to Assessing Human Performance in Nuclear Power Plant Control Room Simulations

    Energy Technology Data Exchange (ETDEWEB)

    Katya L Le Blanc; Ronald L Boring; David I Gertman

    2001-11-01

    With the increased use of digital systems in Nuclear Power Plant (NPP) control rooms comes a need to thoroughly understand the human performance issues associated with digital systems. A common way to evaluate human performance is to test operators and crews in NPP control room simulators. However, it is often challenging to characterize human performance in meaningful ways when measuring performance in NPP control room simulations. A review of the literature in NPP simulator studies reveals a variety of ways to measure human performance in NPP control room simulations including direct observation, automated computer logging, recordings from physiological equipment, self-report techniques, protocol analysis and structured debriefs, and application of model-based evaluation. These methods and the particular measures used are summarized and evaluated.

  13. Teoría de agencia (TA: supuestos teóricos aplicables a la gestión universitaria

    Directory of Open Access Journals (Sweden)

    Francisco Aníbal Ganga Contreras

    2015-07-01

    Full Text Available : En Iberoamérica han surgido inquietudes con respecto a la efectividad de las universidades, particularmente respecto de su calidad. Se tiene como premisa indiscutida que la gestión del gobierno universitario es uno de los factores determinantes para mejorar el quehacer administrativo y, desde ahí, las tareas académicas. El propósito de este trabajo es realizar un análisis desde la teoría de agencia (TA como una aproximación que puede ayudar a detectar y corregir problemas de gestión del gobierno universitario, entendiendo que se trata de una deriva teórica y no doctrinaria. Para lograr este propósito, se procedió a revisar más de un centenar de textos y artículos publicados en revistas académicas de prestigio internacional. Como hallazgos relevantes, se pueden destacar la identificación y la reflexión en torno a elementos y factores determinantes considerados por la TA, que son aplicables al mundo de la gestión universitaria (GU.

  14. Grafía, el trabajo en una agencia de prensa especializada en infográficos (6

    Directory of Open Access Journals (Sweden)

    Julio Alonso

    1998-01-01

    Full Text Available El periodista gráfico Julio Alonso conoció los 'secretos' de la infografía en el diario 'El País' (Madrid y después se ocupó de la dirección de arte de la Agencia Grafía, la primera entidad de este tipo dedicada a la realización de infografía para medios impresos. El trabajo aquí presentado data del periodo en que Alonso trabajó en Grafía y corresponde a la lección impartida en el curso sobre infografía periodística celebrado en la Universidad Internacional Menéndez y Pelayo, en su sede de Cuenca. Se trata de la sexta entrega del libro colectivo sobre infografía periodística, iniciado por Mario R. García, del Poynter Institute de Florida (EE.UU., y continuado por Elio Leturia, grafista del diario norteamericano The Detroit Free Press; por el catedrático de Periodismo José Manuel de Pablos, de la Universidad de La Laguna (Canarias; el ex director de arte del diario Le Monde (París, Michel Gafré, y el profesor Kevin G. Barnhurst, de la Siracuse University.

  15. Nuclear safeguards; Salvaguardias nucleares

    Energy Technology Data Exchange (ETDEWEB)

    Zurron, O.

    2015-07-01

    Safeguards control at the Juzbado Plant is implemented through the joint IAEA/EURATOM partnership approach in force within the European Union for all nuclear facilities. this verification agreement is designed to minimize burden on the operators whilst ensuring that both inspectorate achieve the objectives related to their respective safeguards regimes. This paper outlines the safeguards approaches followed by the inspectorate and the particularities of the Juzbado Plants nuclear material accountancy and control system. (Authors)

  16. Model-Free Coordinated Control for MHTGR-Based Nuclear Steam Supply Systems

    Directory of Open Access Journals (Sweden)

    Zhe Dong

    2016-01-01

    Full Text Available The modular high temperature gas-cooled reactor (MHTGR is a typical small modular reactor (SMR that offers simpler, standardized and safer modular design by being factory built, requiring smaller initial capital investment, and having a shorter construction period. Thanks to its small size, the MHTGRs could be beneficial in providing electric power to remote areas that are deficient in transmission or distribution and in generating local power for large population centers. Based on the multi-modular operation scheme, the inherent safety feature of the MHTGRs can be applicable to large nuclear plants of any desired power rating. The MHTGR-based nuclear steam supplying system (NSSS is constituted by an MHTGR, a side-by-side arranged helical-coil once-through steam generator (OTSG and some connecting pipes. Due to the side-by-side arrangement, there is a tight coupling effect between the MHTGR and OTSG. Moreover, there always exists the parameter perturbation of the NSSSs. Thus, it is meaningful to study the model-free coordinated control of MHTGR-based NSSSs for safe, stable, robust and efficient operation. In this paper, a new model-free coordinated control strategy that regulates the nuclear power, MHTGR outlet helium temperature and OTSG outlet overheated steam temperature by properly adjusting the control rod position, helium flowrate and feed-water flowrate is established for the MHTGR-based NSSSs. Sufficient conditions for the globally asymptotic closed-loop stability is given. Finally, numerical simulation results in the cases of large range power decrease and increase illustrate the satisfactory performance of this newly-developed model-free coordinated NSSS control law.

  17. Laser bonding with ICG-infused chitosan patches: preliminary experiences in suine dura mater and vocal folds

    Science.gov (United States)

    Rossi, Francesca; Matteini, Paolo; Ratto, Fulvio; Pini, Roberto; Iacoangeli, Maurizio; Giannoni, Luca; Fortuna, Damiano; Di Cicco, Emiliano; Corbara, Sylwia; Dallari, Stefano

    2014-05-01

    Laser bonding is a promising minimally invasive approach, emerging as a valid alternative to conventional suturing techniques. It shows widely demonstrated advantages in wound treatment: immediate closuring effect, minimal inflammatory response and scar formation, reduced healing time. This laser based technique can overcome the difficulties in working through narrow surgical corridors (e.g. the modern "key-hole" surgery as well as the endoscopy setting) or in thin tissues that are impossible to treat with staples and/or stitches. We recently proposed the use of chitosan matrices, stained with conventional chromophores, to be used in laser bonding of vascular tissue. In this work we propose the same procedure to perform laser bonding of vocal folds and dura mater repair. Laser bonding of vocal folds is proposed to avoid the development of adhesions (synechiae), after conventional or CO2 laser surgery. Laser bonding application in neurosurgery is proposed for the treatment of dural defects being the Cerebro Spinal Fluid leaks still a major issue. Vocal folds and dura mater were harvested from 9-months old porks and used in the experimental sessions within 4 hours after sacrifice. In vocal folds treatment, an IdocyanineGreen-infused chitosan patch was applied onto the anterior commissure, while the dura mater was previously incised and then bonded. A diode laser emitting at 810 nm, equipped with a 600 μm diameter optical fiber was used to weld the patch onto the tissue, by delivering single laser spots to induce local patch/tissue adhesion. The result is an immediate adhesion of the patch to the tissue. Standard histology was performed, in order to study the induced photothermal effect at the bonding sites. This preliminary experimental activity shows the advantages of the proposed technique in respect to standard surgery: simplification of the procedure; decreased foreign-body reaction; reduced inflammatory response; reduced operating times and better handling in

  18. Biological Effects of Clinically Relevant CoCr Nanoparticles in the Dura Mater: An Organ Culture Study

    Directory of Open Access Journals (Sweden)

    Iraklis Papageorgiou

    2014-06-01

    Full Text Available Medical interventions for the treatment of spinal disc degeneration include total disc replacement and fusion devices. There are, however, concerns regarding the generation of wear particles by these devices, the majority of which are in the nanometre sized range with the potential to cause adverse biological effects in the surrounding tissues. The aims of this study were to develop an organ culture model of the porcine dura mater and to investigate the biological effects of CoCr nanoparticles in this model. A range of histological techniques were used to analyse the structure of the tissue in the organ culture. The biological effects of the CoCr wear particles and the subsequent structural changes were assessed using tissue viability assays, cytokine assays, histology, immunohistochemistry, and TEM imaging. The physiological structure of the dura mater remained unchanged during the seven days of in vitro culture. There was no significant loss of cell viability. After exposure of the organ culture to CoCr nanoparticles, there was significant loosening of the epithelial layer, as well as the underlying collagen matrix. TEM imaging confirmed these structural alterations. These structural alterations were attributed to the production of MMP-1, -3, -9, -13, and TIMP-1. ELISA analysis revealed that there was significant release of cytokines including IL-8, IL-6, TNF-α, ECP and also the matrix protein, tenascin-C. This study suggested that CoCr nanoparticles did not cause cytotoxicity in the dura mater but they caused significant alterations to its structural integrity that could lead to significant secondary effects due to nanoparticle penetration, such as inflammation to the local neural tissue.

  19. Results of automatic system implementation for the friction control rods execution in Cofrentes nuclear power plant

    Energy Technology Data Exchange (ETDEWEB)

    Curiel, M. [Logistica y Acondicionamientos Industriales SAU, Sorolla Center, local 10, Av. de las Cortes Valencianas, 46015 Valencia (Spain); Palomo, M. J. [ISIRYM, Universidad Politecnica de Valencia, Camino de Vera s/n, Valencia (Spain); Urrea, M. [Iberdrola Generacion S. A., Central Nuclear Cofrentes, Carretera Almansa Requena s/n, 04662 Cofrentes, Valencia (Spain); Arnaldos, A., E-mail: m.curiel@lainsa.co [TITANIA Servicios Tecnologicos SL, Sorolla Center, local 10, Av. de las Cortes Valencianas No. 58, 46015 Valencia (Spain)

    2010-10-15

    The purpose of this presentation is to show the obtained results in Cofrentes nuclear power plant (Spain) of control rods Pcc/24 friction test procedure. In order to perform this, a control rod friction test system has been developed. Principally, this system consists on software and data acquisition hardware that obtains and analyzes the control rod pressure variation on which the test is being made. The Pcc/24 procedure objective is to detect an excessive friction in the control rod movement that could cause a control rod drive movement slower than usual. This test is necessary every time that an anomalous alteration is produced in the reactor core that could affect to a fuel rod, and it is executed before the time measure of control rods rapid scram test of the affected rods. This test has to be carried out to all the reactor control rods and takes valuable time during plant refuelling. So, by means of an automatic system to perform the test, we obtain an important time saving during refuelling. On the other hand, the on-line monitoring of the control rod insertion and changes in differential pressure, permits a control rod operation fast and safe validation. Moreover, an automatic individual report of every rod is generated by the system and a final global result report of the entire test developed in refuelling is generated. The mentioned reports can be attached directly to the procedure documents obtaining an office data processing important saving time. (Author)

  20. Results of automatic system implementation for the friction control rods execution in Cofrentes nuclear power plant

    Energy Technology Data Exchange (ETDEWEB)

    Palomo, M., E-mail: mpalomo@iqn.upv.es [Universidad Politecnica de Valencia (UPV) (Spain); Urrea, M., E-mail: matias.urrea@iberdrola.es [Iberdrola Generacion S.A. Valencia (Spain). C.N. Cofrentes; Curiel, M., E-mail: m.curiel@lainsa.com [Logistica y Acondicionamientos Industriales (LAINSA), Valencia (Spain); Arnaldos, A., E-mail: a.arnaldos@titaniast.com [TITANIA Servicios Teconologicos, Valencia (Spain)

    2011-07-01

    The purpose of this presentation is to show the obtained results in Cofrentes Nuclear Power Plant (Spain) of Control Rods PCC/24 Friction Test Procedure. In order to perform this, a Control Rod Friction Test System has been developed. Principally, this system consists on software and data acquisition hardware that obtains and analyzes the control rod pressure variation on which the test is being made. The PCC/24 Procedure objective is to detect an excessive friction in the control rod movement that could cause a CRD (Control Rod Drive) movement slower than usual. This test is necessary every time that an anomalous alteration is produced in the reactor core that could affect to a fuel rod, and it is executed before the time measure of control rods rapid scram test of the affected rods. This test has to be carried out to all the reactor control rods and takes valuable time during plant refuelling. So, by means of an automatic system to perform the test, we obtain an important time saving during refuelling. On the other hand, the on-line monitoring of the control rod insertion and changes in differential pressure, permits a control rod operation fast and safe validation. Moreover, an automatic individual report of every rod is generated by the system and a final global result report of the entire test developed in refuelling is generated. The mentioned reports can be attached directly to the procedure documents obtaining an office data processing important saving time.(author)

  1. Applying human factors to the design of control centre and workstation of a nuclear reactor

    Energy Technology Data Exchange (ETDEWEB)

    Santos, Isaac J.A. Luquetti dos; Carvalho, Paulo V.R.; Goncalves, Gabriel de L., E-mail: luquetti@ien.gov.br [Instituto de Engenharia Nuclear (IEN/CNEN-RJ), Rio de Janeiro, RJ (Brazil); Souza, Tamara D.M.F.; Falcao, Mariana A. [Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro, RJ (Brazil). Dept. de Desenho Industrial

    2013-07-01

    Human factors is a body of scientific factors about human characteristics, covering biomedical, psychological and psychosocial considerations, including principles and applications in the personnel selection areas, training, job performance aid tools and human performance evaluation. Control Centre is a combination of control rooms, control suites and local control stations which are functionally related and all on the same site. Digital control room includes an arrangement of systems, equipment such as computers and communication terminals and workstations at which control and monitoring functions are conducted by operators. Inadequate integration between control room and operators reduces safety, increases the operation complexity, complicates operator training and increases the likelihood of human errors occurrence. The objective of this paper is to present a specific approach for the conceptual and basic design of the control centre and workstation of a nuclear reactor used to produce radioisotope. The approach is based on human factors standards, guidelines and the participation of a multidisciplinary team in the conceptual and basic phases of the design. Using the information gathered from standards and from the multidisciplinary team, an initial sketch 3D of the control centre and workstation are being developed. (author)

  2. Advantages of a program of quality control in the nuclear medicine equipment; Ventajas de un programa de control de calidad en los equipos de medicina nuclear

    Energy Technology Data Exchange (ETDEWEB)

    Trujillo Z, F.E.; Argumosa, E. [Departamento de Medicina Nuclear del Instituto Nacional de Cancerologia, Tlalpan, Mexico D.F. (Mexico); Herrera R, M.R. [Hospital Infantil de Mexico ' Federico Gomez' , Mexico D.F. (Mexico)

    2007-07-01

    In Nuclear Medicine more 90% of the entirety of the carried out procedures its are with diagnostic ends where it is acquired one or several images. This makes indispensable to have an appropriate operation of the dedicated equipment to produce images and also of those non former images, as the activity caliper, to assure an appropriate quality diagnoses not from the images and the correct dose administration to the patient. In this work the main calibrations that should be carried out and an example of the program of quality control of a gamma camera mark Siemens and model E.CAM are presented. Considerations that should take as for the radiological protection are exposed. Comments on the parameters that correct the required calibrations and the images taken place by an operation or inadequate calibrations are included. In conclusion, the necessity of a program that it contains as minimum the quality control of the gamma cameras and of the activity caliper, having as main advantages a good image quality diagnoses and to minimize the dose imparted the patient are exposed. (Author)

  3. Quality assessment of radiopharmaceuticals in nuclear medicine services at Northeast states, Brazil; Avaliacao da qualidade de radiofarmacos em servicos de medicina nuclear de estados da regiao nordeste

    Energy Technology Data Exchange (ETDEWEB)

    Andrade, Wellington Gomes de

    2012-07-01

    The radiopharmaceuticals are used in the field nuclear medicine services (NMS) as tracer in the diagnoses and treatment of many diseases. Radiopharmaceuticals used in nuclear medicine and usually have a minimum of pharmacological effect. The procedures for labelling Radiopharmaceuticals should be observed in order to minimize risks to patients, employees and individuals from the public, and to be administered in humans, must be sterile and free of pyrogens and possess elements all measures of quality controls required a conventional drug. The 'Agencia Nacional de Vigilancia Sanitaria (ANVISA)' in its 'Resolucao de Diretoria Colegiada' (RDC) No. 38 of June 4{sup th} 2008, decided that the NMS must perform quality control in the generators eluate and radiopharmaceuticals according to recommendations of manufacturers and scientific evidence accepted by ANVISA. Thus, this study proposes to evaluate the quality of the generator {sup 99M}o-{sup 99m}Tc eluate and radiopharmaceuticals labeled with {sup 99m}Tc used in most NMS of some states in the Northeast, in relation to radionuclide, chemical, radiochemical purity and pH and promote the inclusion of procedure for quality control of radiopharmaceuticals in routine NMS. The results show that 90% radionuclidic purity, 98.2% purity chemical and radiochemical purity of 46% and 100% of the eluates are in agreement with international pharmacopoeias; already radiopharmaceuticals showed 82.6% purity and all radiochemical pH values are also in accordance with international pharmacopoeias. Even with so many positive results, staff the majority of MNS was not able to perform the quality control of the eluates and radiopharmaceuticals. Showing the importance of implementing of quality control programs of the eluates and radiopharmaceuticals in nuclear medicine. (author)

  4. EARLY-STAGE DESIGN AND EVALUATION FOR NUCLEAR POWER PLANT CONTROL ROOM UPGRADES

    Energy Technology Data Exchange (ETDEWEB)

    Ronald L. Boring; Jeffrey C. Joe; Thomas A. Ulrich; Roger T. Lew

    2015-03-01

    As control rooms are modernized with new digital systems at nuclear power plants, it is necessary to evaluate operator performance with these systems as part of a verification and validation process. While there is regulatory and industry guidance for some modernization activities, there are no well defined standard processes or predefined metrics available for assessing what is satisfactory operator interaction with new systems, especially during the early design stages. This paper proposes a framework defining the design process and metrics for evaluating human system interfaces as part of control room modernization. The process and metrics are generalizable to other applications and serve as a guiding template for utilities undertaking their own control room modernization activities.

  5. Real-time corrosion control system for cathodic protection of buried pipes for nuclear power plant

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Ki Tae; Kim, Hae Woong; Kim, Young Sik [School of Materials Science and Engineering, Andong National University, Andong (Korea, Republic of); Chang, Hyun Young; Lim, Bu Taek; Park, Heung Bae [Power Engineering Research Institute, KEPCO Engineering and Construction Company, Seongnam (Korea, Republic of)

    2015-02-15

    Since the operation period of nuclear power plants has increased, the degradation of buried pipes gradually increases and recently it seems to be one of the emerging issues. Maintenance on buried pipes needs high quality of management system because outer surface of buried pipe contacts the various soils but inner surface reacts with various electrolytes of fluid. In the USA, USNRC and EPRI have tried to manage the degradation of buried pipes. However, there is little knowledge about the inspection procedure, test and manage program in the domestic nuclear power plants. This paper focuses on the development and build-up of real-time monitoring and control system of buried pipes. Pipes to be tested are tape-coated carbon steel pipe for primary component cooling water system, asphalt-coated cast iron pipe for fire protection system, and pre-stressed concrete cylinder pipe for sea water cooling system. A control system for cathodic protection was installed on each test pipe which has been monitored and controlled. For the calculation of protection range and optimization, computer simulation was performed using COMSOL Multiphysics (Altsoft co.)

  6. Development of a remote controlled robot system for monitoring nuclear power plant

    Energy Technology Data Exchange (ETDEWEB)

    Woo, Hee Gon; Song, Myung Jae; Shin, Hyun Bum; Oh, Gil Hwan; Maeng, Sung Jun; Choi, Byung Jae; Chang, Tae Woo [Korea Electric Power Research Institute, Taejon (Korea, Republic of); Lee, Bum Hee; Yoo, Jun; Choi, Myung Hwan; Go, Nak Yong; Lee, Kee Dong; Lee, Young Dae; Cho, Hae Kyeng; Nam, Yoon Suk [Electric and Science Research Center, (Korea, Republic of)

    1996-12-31

    It`s a final report of the development of remote controlled robot system for monitoring the facilities in nuclear power plant and contains as follows, -Studying the technologies in robot developments and analysing the requirements and working environments - Development of the test mobile robot system - Development of the mobile-robot - Development of the Mounted system on the Mobile robot - Development of the Monitoring system - Mobil-robot applications and future study. In this study we built the basic technologies and schemes for future robot developments and applications. (author). 20 refs., figs.

  7. Modal seismic analysis of a nuclear power plant control panel and comparison with SAP 4

    Science.gov (United States)

    Pamidi, M. R.; Pamidi, P. R.

    1976-01-01

    The application of NASTRAN to seismic analysis by considering the example of a nuclear power plant control panel was considered. A modal analysis of a three-dimensional model of the panel, consisting of beam and quadri-lateral membrane elements, is performed. Using the results of this analysis and a typical response spectrum of an earthquake, the seismic response of the structure is obtained. ALTERs required to the program in order to compute the maximum modal responses as well as the resultant response are given. The results are compared with those obtained by using the SAP IV computer program.

  8. Visualisation of the intact dura mater and brain surface in infant autopsies: a minimally destructive technique for the post-mortem assessment of head injury.

    Science.gov (United States)

    Cheshire, Emma C; Malcomson, Roger D G; Rutty, Guy N; James, Deryk S

    2015-03-01

    During the post-mortem examination of babies and young children, it is important to be able to visualise the brain and its coverings, particularly in cases where a head injury is likely to have occurred. In this paper, we present an improved method for removal of the calvarial bones in infant autopsies to enable viewing of the dura mater and brain. In contrast to the standard post-mortem procedure for observing and removing the brain, this novel technique is minimally disruptive, allowing the dura mater to remain undamaged. Specialised paediatric neurosurgical tools were used to remove the skull bones from 23 neonates, infants and young children during post-mortem examination. In 21 of our 23 cases, the calvarial bones were removed successfully with the dura mater remaining intact. In one case, there was a thickening of the dura mater which created a strong adherence of this membrane to the bone. In another case, the dura mater was slightly damaged due to the inexperience of the operator in using the neurosurgical tools. This method of calvarial bone removal reduces the degree of post-mortem artefact and enhances the ability to observe and photographically document autopsy findings, including the artefact-free detection of signs of injury such as epidural or subdural haematoma, and brain swelling. This technique has now become a routine practise in both of our units to remove the skull bones in infant/young children post-mortem examinations.

  9. Nuclear Data Library Effects on Fast to Thermal Flux Shapes Around PWR Control Rod Tips

    Science.gov (United States)

    Vasiliev, A.; Ferroukhi, H.; Zhu, T.; Pautz, A.

    2014-04-01

    The development of a high-fidelity computational scheme to estimate the accumulated fluence at the tips of PWR control rods (CR) has been initiated at the Paul Scherrer Institut (PSI). Both the fluence from high-energy (E>1 MeV) neutrons as well as for the thermal range (EMCNPX model that is then used to compute the neutron fluxes. A particular aspect that needs scrutiny is the ability of the MCNPX-based calculation methodology to accurately predict the flux shapes along the control rod surfaces, especially for fully withdrawn CRs. In that case, the tip is located a short distance above the core/reflector interface and since this situation corresponds to a large part of reactor operation, the accumulated fluence will highly depend on the achieved calculation accuracy and precision in this non-fueled zone. The objective of the work presented in this paper is to quantify the influence of nuclear data on the calculated fluxes at the CR tips by (1) conducting a systematic comparison of modern neutron cross-section libraries, including JENDL-4.0, JEFF-3.1.1 and ENDF/B-VII.0, and (2) by quantifying the uncertainties in the neutron flux calculations with the help of available neutron cross-section variances/covariances data. For completeness, the magnitude of these nuclear data-based uncertainties is also assessed in relation to the influence from other typical sources of modeling uncertainties/biases.

  10. Nutrient-sensing nuclear receptors PPARα and FXR control liver energy balance.

    Science.gov (United States)

    Preidis, Geoffrey A; Kim, Kang Ho; Moore, David D

    2017-04-03

    The nuclear receptors PPARα (encoded by NR1C1) and farnesoid X receptor (FXR, encoded by NR1H4) are activated in the liver in the fasted and fed state, respectively. PPARα activation induces fatty acid oxidation, while FXR controls bile acid homeostasis, but both nuclear receptors also regulate numerous other metabolic pathways relevant to liver energy balance. Here we review evidence that they function coordinately to control key nutrient pathways, including fatty acid oxidation and gluconeogenesis in the fasted state and lipogenesis and glycolysis in the fed state. We have also recently reported that these receptors have mutually antagonistic impacts on autophagy, which is induced by PPARα but suppressed by FXR. Secretion of multiple blood proteins is a major drain on liver energy and nutrient resources, and we present preliminary evidence that the liver secretome may be directly suppressed by PPARα, but induced by FXR. Finally, previous studies demonstrated a striking deficiency in bile acid levels in malnourished mice that is consistent with results in malnourished children. We present evidence that hepatic targets of PPARα and FXR are dysregulated in chronic undernutrition. We conclude that PPARα and FXR function coordinately to integrate liver energy balance.

  11. Nuclear hormone receptor NHR-49 controls fat consumption and fatty acid composition in C. elegans.

    Directory of Open Access Journals (Sweden)

    Marc R Van Gilst

    2005-02-01

    Full Text Available Mammalian nuclear hormone receptors (NHRs, such as liver X receptor, farnesoid X receptor, and peroxisome proliferator-activated receptors (PPARs, precisely control energy metabolism. Consequently, these receptors are important targets for the treatment of metabolic diseases, including diabetes and obesity. A thorough understanding of NHR fat regulatory networks has been limited, however, by a lack of genetically tractable experimental systems. Here we show that deletion of the Caenorhabditis elegans NHR gene nhr-49 yielded worms with elevated fat content and shortened life span. Employing a quantitative RT-PCR screen, we found that nhr-49 influenced the expression of 13 genes involved in energy metabolism. Indeed, nhr-49 served as a key regulator of fat usage, modulating pathways that control the consumption of fat and maintain a normal balance of fatty acid saturation. We found that the two phenotypes of the nhr-49 knockout were linked to distinct pathways and were separable: The high-fat phenotype was due to reduced expression of enzymes in fatty acid beta-oxidation, and the shortened adult life span resulted from impaired expression of a stearoyl-CoA desaturase. Despite its sequence relationship with the mammalian hepatocyte nuclear factor 4 receptor, the biological activities of nhr-49 were most similar to those of the mammalian PPARs, implying an evolutionarily conserved role for NHRs in modulating fat consumption and composition. Our findings in C. elegans provide novel insights into how NHR regulatory networks are coordinated to govern fat metabolism.

  12. Advanced Outage and Control Center: Strategies for Nuclear Plant Outage Work Status Capabilities

    Energy Technology Data Exchange (ETDEWEB)

    Gregory Weatherby

    2012-05-01

    The research effort is a part of the Light Water Reactor Sustainability (LWRS) Program. LWRS is a research and development program sponsored by the Department of Energy, performed in close collaboration with industry to provide the technical foundations for licensing and managing the long-term, safe and economical operation of current nuclear power plants. The LWRS Program serves to help the US nuclear industry adopt new technologies and engineering solutions that facilitate the continued safe operation of the plants and extension of the current operating licenses. The Outage Control Center (OCC) Pilot Project was directed at carrying out the applied research for development and pilot of technology designed to enhance safe outage and maintenance operations, improve human performance and reliability, increase overall operational efficiency, and improve plant status control. Plant outage management is a high priority concern for the nuclear industry from cost and safety perspectives. Unfortunately, many of the underlying technologies supporting outage control are the same as those used in the 1980’s. They depend heavily upon large teams of staff, multiple work and coordination locations, and manual administrative actions that require large amounts of paper. Previous work in human reliability analysis suggests that many repetitive tasks, including paper work tasks, may have a failure rate of 1.0E-3 or higher (Gertman, 1996). With between 10,000 and 45,000 subtasks being performed during an outage (Gomes, 1996), the opportunity for human error of some consequence is a realistic concern. Although a number of factors exist that can make these errors recoverable, reducing and effectively coordinating the sheer number of tasks to be performed, particularly those that are error prone, has the potential to enhance outage efficiency and safety. Additionally, outage management requires precise coordination of work groups that do not always share similar objectives. Outage

  13. An integrated software testing framework for FGA-based controllers in nuclear power plants

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Jae Yeob; Kim, Eun Sub; Yoo, Jun Beom [Div. of Computer Science and Engineering, Konkuk University, Seoul (Korea, Republic of); Lee, Young Jun; Choi, Jong Gyun [MMIS Lab., Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2016-04-15

    Field-programmable gate arrays (FPGAs) have received much attention from the nuclear industry as an alternative platform to programmable logic controllers for digital instrumentation and control. The software aspect of FPGA development consists of several steps of synthesis and refinement, and also requires verification activities, such as simulations that are performed individually at each step. This study proposed an integrated software-testing framework for simulating all artifacts of the FPGA software development simultaneously and evaluating whether all artifacts work correctly using common oracle programs. This method also generates a massive number of meaningful simulation scenarios that reflect reactor shutdown logics. The experiment, which was performed on two FPGA software implementations, showed that it can dramatically save both time and costs.

  14. Real time virtual reality 3D animation and control system for nuclear service robotics

    Energy Technology Data Exchange (ETDEWEB)

    Petrosky, L.J. [Westinghouse Electric Corporation (United States)

    1998-07-01

    The ROSACAD robotic control system developed by Westinghouse Electric Corporation provides a robot operator with real time 3D virtual reality animation of the robot in its environment and provides on-line look ahead collision avoidance. The operator interface is ideal for systems that use teleoperation, or those in which the robot's work envelope is congested with many obstacles. The operations software uses object-oriented coding, which allows easy extension to new applications and is specifically design to integrate teleoperation interpersed with autonomous sequences. Any robot and environment can he modeled through the use of the ROBCAD solid modeling software, including the presence of moving obstacles. ROSACAD is a generic interface and control system that has beer applied in many diverse robotic systems ranging from nuclear steam generator service arms to pipe crawlers. (authors)

  15. Digital control systems in nuclear power plants: Failure information, modeling concepts, and applications

    Energy Technology Data Exchange (ETDEWEB)

    Galyean, W.J.

    1993-06-23

    This report briefly describes some current applications of advanced computerized digital display and control systems at US commercial nuclear power plants and presents the results of a literature search that was made to gather information on the reliability of these systems. Both hardware and software reliability were addressed in this review. Only limited failure rate information was found, with the chemical process industry being the primary source of information on hardware failure rates and expert opinion the primary source for software failure rates. Safety-grade digital control systems are typically installed on a functional like-for-like basis, replacing older analog systems without substantially changing interactions with other plant systems. Future work includes performing a limited probabilistic risk assessment of a representative DCS to assess its risk significance.

  16. Digital control systems in nuclear power plants: Failure information, modeling concepts, and applications. Revision 1

    Energy Technology Data Exchange (ETDEWEB)

    Galyean, W.J.

    1993-06-23

    This report briefly describes some current applications of advanced computerized digital display and control systems at US commercial nuclear power plants and presents the results of a literature search that was made to gather information on the reliability of these systems. Both hardware and software reliability were addressed in this review. Only limited failure rate information was found, with the chemical process industry being the primary source of information on hardware failure rates and expert opinion the primary source for software failure rates. Safety-grade digital control systems are typically installed on a functional like-for-like basis, replacing older analog systems without substantially changing interactions with other plant systems. Future work includes performing a limited probabilistic risk assessment of a representative DCS to assess its risk significance.

  17. Estructura y agencia en la migración infantil centroamericana

    OpenAIRE

    Acuña González, Guillermo E.

    2016-01-01

    Al promediar el año 2014 se activaron voces que alertaban sobre la presencia de decenas de miles de niños y niñas migrantes centroamericanos tratando de cruzar la frontera entre México y Estados Unidos. Las respuestas elaboradas por las autoridades migratorias y estatales de ambos países privilegiaron un esquema de seguridad y control, sin atender las especificidades de esta migración. Los discursos públicos homogeneizaron las miradas sobre quienes hacían parte de estos procesos migratorios e...

  18. Engineering light-inducible nuclear localization signals for precise spatiotemporal control of protein dynamics in living cells.

    Science.gov (United States)

    Niopek, Dominik; Benzinger, Dirk; Roensch, Julia; Draebing, Thomas; Wehler, Pierre; Eils, Roland; Di Ventura, Barbara

    2014-07-14

    The function of many eukaryotic proteins is regulated by highly dynamic changes in their nucleocytoplasmic distribution. The ability to precisely and reversibly control nuclear translocation would, therefore, allow dissecting and engineering cellular networks. Here we develop a genetically encoded, light-inducible nuclear localization signal (LINuS) based on the LOV2 domain of Avena sativa phototropin 1. LINuS is a small, versatile tag, customizable for different proteins and cell types. LINuS-mediated nuclear import is fast and reversible, and can be tuned at different levels, for instance, by introducing mutations that alter AsLOV2 domain photo-caging properties or by selecting nuclear localization signals (NLSs) of various strengths. We demonstrate the utility of LINuS in mammalian cells by controlling gene expression and entry into mitosis with blue light.

  19. Risks and challenges associated with the design and construction of a nuclear power plant; Control de riesgos y retos asociados al diseno y construccion de una central nuclear

    Energy Technology Data Exchange (ETDEWEB)

    Liebana Martinez, B.; Armas Garcia, A.; Martinez Gozalo, I.

    2011-07-01

    The construction of a nuclear power plant project, considering the period prior to the operation of the plant, requires a very strict risk control to ensure compliance with a series of challenges. The present paper identifying the most important challenges facing the construct ability and license requirements of the process, identifying the interfaces and proposing a methodology of construction to meet the challenge of a construction process in 5 years.

  20. ‘Una ventanita’: Vida cotidiana de las dueñas de casa y agencia de las máquinas tragamonedas en Chile

    Directory of Open Access Journals (Sweden)

    Francisco Olivos Ravé

    2012-07-01

    Full Text Available Este artículo intenta dar respuesta de forma etnográfica a la pregunta de cuál es el sentido que ocupan las máquinas tragamonedas y la agencia que estas tienen sobre la vida cotidiana de las dueñas de casa de un barrio de clase media baja en la comuna de San Bernardo, Santiago. Se descubre que el juego en las máquinas tragamonedas no constituye un momento extraordinario, sino que es parte de la rutina, pero a la vez permite una ruptura de la simultaneidad del tiempo libre con el de las labores del hogar que caracteriza a otras actividades como ver televisión. Sin embargo, gracias al enfoque de la teoría del actor red es posible observar que la agencia de las máquinas tragamonedas canaliza el escape de lo que significa la casa, es decir, de las responsabilidades y de los problemas familiares. Se genera, por otra parte, un encuentro de las dueñas de casa con su self. Asimismo, la agencia de las máquinas tragamonedas desencadena controversias en la familia volviéndola parte de la red que se forma en torno el juego. Finalmente, se plantea que las decisiones que se tomen en torno a la legislación sobre el juego deben tener en cuenta una traducción que permita comprender la lógica del juego en la vida cotidiana de las dueñas de casa y de los jugadores en general.

  1. La Elección Estratégica y el Enfoque de la Teoría de Agencia – Un Ensayo Teórico

    Directory of Open Access Journals (Sweden)

    Rosalia Barbosa Lavarda

    2011-09-01

    Full Text Available definición de los factores, se puede decir que la concepción y visión directiva, con el enfoque de la lógica dominante y de la strategic choice elige, con su estrategia, el entorno o el mercado en el cual la empresa actuará. Por su vez el condicionamiento contingente influye en los productos o servicios que la empresa obtendrá, lo cual condiciona los tipos de trabajo y el sistema técnico o tecnología que la empresa utilizará, que a su vez, conduce las formas y necesidades organizativas. El entendimiento es que hay un marco conceptual en torno de la concepción y visión directiva, el condicionamiento contingente, los tipos de trabajo y el enfoque de la teoría de agencia. Ese pensamiento va se estableciendo en lo largo del trabajo a con el fin de contestar la siguiente cuestión de investigación: ¿Cómo y a través de que variables la organización puede minimizar los problemas de agencia y mejorar la gestión del trabajo? Cuanto a la forma de desarrollo del estudio ese se caracteriza como un ensayo teórico (Whetten, 2003, una vez que revisó conceptos y teorías en trabajos,seminales de manera a encontrar la adecuada gestión (fit de las variables de diseño para posibilitar la propuesta de una mejor gestión de los diferentes tipos de trabajo, minimizando los problemas de agencia, principalmente para organizaciones que se dan cuenta que el entorno siempre influye o condiciona los productos y servicios de la empresa, previamente concebidos por la elección estratégica.

  2. Impact of holmium fibre laser radiation (λ = 2.1 μm) on the spinal cord dura mater and adipose tissue

    Science.gov (United States)

    Filatova, S. A.; Kamynin, V. A.; Ryabova, A. V.; Loshchenov, V. B.; Zelenkov, P. V.; Zolotovskii, I. O.; Tsvetkov, V. B.; Kurkov, A. S.

    2015-08-01

    The impact of holmium fibre laser radiation on the samples of biologic tissues (dura mater of spinal cord and adipose tissue with interlayers of muscle) is studied. The experimental results are evaluated by the size of carbonisation and coagulation necrosis zones. The experiment shows that in the case of irradiation of the spinal cord dura mater samples the size of carbonisation and coagulation necrosis zones is insignificant. In the adipose tissue the carbonisation zone is also insignificant, but the region of cellular structure disturbance is large. In the muscle tissue the situation is opposite. The cw laser operation provides clinically acceptable degree of destruction in tissue samples with a minimal carbonisation zone.

  3. Development of a nuclear reactor control system simulator using virtual instruments

    Energy Technology Data Exchange (ETDEWEB)

    Pinto, Antonio Juscelino; Mesquita, Amir Zacarias; Lameiras, Fernando Soares, E-mail: ajp@cdtn.b, E-mail: amir@cdtn.b, E-mail: fsl@cdtn.b [Centro de Desenvolvimento da Tecnologia Nuclear (CDTN/CNEN-MG), Belo Horizonte, MG (Brazil)

    2011-07-01

    The International Atomic Energy Agency recommends the use of safety and friendly interfaces for monitoring and controlling the operational parameters of the nuclear reactors. This article describes a digital system being developed to simulate the behavior of the operating parameters using virtual instruments. The control objective is to bring the reactor power from its source level (mW) to a full power (kW). It is intended for education of basic reactor neutronic and thermohydraulic principles such as the multiplication factor, criticality, reactivity, period, delayed neutron, control by rods, fuel and coolant temperatures, power, etc. The 250 kW IPR-R1 TRIGA research reactor at Nuclear Technology Development Centre - CDTN was used as reference. TRIGA reactors, developed by General Atomics (GA), are the most widely used research reactor in the world. The simulator system is being developed using the LabVIEW (Laboratory Virtual Instruments Engineering Workbench) software, considering the modern concept of virtual instruments (VI's) using electronic processor and visual interface in video monitor. The main purpose of the system is to provide training tools for instructors and students, allowing navigating by user-friendly operator interface and monitoring tendencies of the operational variables. It will be an interactive tool for training and teaching and could be used to predict the reactor behavior. Some scenarios are presented to demonstrate that it is possible to know the behavior of some variables from knowledge of input parameters. The TRIGA simulator system will allow the study of parameters, which affect the reactor operation, without the necessity of using the facility. (author)

  4. Integrated Cost and Schedule Control Systems for Nuclear Power Plant Construction: Leveraging Strategic Advantages to Owners and EPC Firms

    Directory of Open Access Journals (Sweden)

    Youngsoo Jung

    2015-01-01

    Full Text Available As the owners expect that the cost and time for nuclear power plant construction would decrease with new entrants into the market, there will be severer competition in the nuclear industry. In order to achieve performance improvement and to attain competitive advantages under the globalized competition, practitioners and researchers in the nuclear industry have recently exerted efforts to develop an advanced and efficient management methodology for the nuclear mega-projects. Among several candidates, integrated cost and schedule control system is of great concern because it can effectively manage the three most important project performances including cost, time, and quality. In this context, the purpose of this paper is to develop a project numbering system (PNS of integrated cost and schedule control system for nuclear power plant construction. Distinct attributes of nuclear power plant construction were investigated first in order to identify influencing variables that characterize real-world implementation of advanced cost and schedule controls. A scenario was then developed and analysed to simulate a case-project. By using this case-project, proposed management requirements, management methods, measurement techniques, data structure, and data collection methods for integrated cost and schedule PNS were illustrated. Finally, findings and implications are outlined, and recommendations for further research are presented.

  5. Cambios en la política de la Agencia de Naciones Unidas para refugiados de Palestina (UNRWA) tras la llegada de Hamas al poder 2002-2010

    OpenAIRE

    Aranguren Zaldúa, Sergio Andrés

    2014-01-01

    Este estudio de caso busca evaluar los cambios en las políticas de la Agencia de Naciones Unidas para los Refugiados de Palestina en Oriente Próximo (UNRWA), luego de la llegada de Hamas al poder en Franja de Gaza en el año 2006. Así, es necesario partir de la creación y consolidación de ambas organizaciones, hasta el 2006, cuando se vieron en la necesidad de armonizar y complementar sus políticas por medio de la educación, para atender y satisfacer las necesidades de la población refugiada p...

  6. Evaluación de los contenidos de información de medicamentos en un grupo de agencias reguladoras de medicamentos

    OpenAIRE

    Gil Rojas, Yaneth

    2016-01-01

    OBJETIVO: Evaluar las diferencias de información publicada por el Invima y otras Autoridades Reguladoras de Medicamentos en relación a un grupo de variables seleccionadas y analizar las diferencias aplicando estrategias de visualización de datos. METODOLOGÍA: Estudio descriptivo de corte transversal, en el cual se comparan las diferencias en la información de medicamentos publicada en las agencias reguladoras de medicamentos. Para la definición de los criterios de comparación, más relevantes ...

  7. Digital Full-Scope Simulation of a Conventional Nuclear Power Plant Control Room, Phase 2: Installation of a Reconfigurable Simulator to Support Nuclear Plant Sustainability

    Energy Technology Data Exchange (ETDEWEB)

    Ronald L. Boring; Vivek Agarwal; Kirk Fitzgerald; Jacques Hugo; Bruce Hallbert

    2013-03-01

    The U.S. Department of Energy’s Light Water Reactor Sustainability program has developed a control room simulator in support of control room modernization at nuclear power plants in the U.S. This report highlights the recent completion of this reconfigurable, full-scale, full-scope control room simulator buildout at the Idaho National Laboratory. The simulator is fully reconfigurable, meaning it supports multiple plant models developed by different simulator vendors. The simulator is full-scale, using glasstop virtual panels to display the analog control boards found at current plants. The present installation features 15 glasstop panels, uniquely achieving a complete control room representation. The simulator is also full-scope, meaning it uses the same plant models used for training simulators at actual plants. Unlike in the plant training simulators, the deployment on glasstop panels allows a high degree of customization of the panels, allowing the simulator to be used for research on the design of new digital control systems for control room modernization. This report includes separate sections discussing the glasstop panels, their layout to mimic control rooms at actual plants, technical details on creating a multi-plant and multi-vendor reconfigurable simulator, and current efforts to support control room modernization at U.S. utilities. The glasstop simulator provides an ideal testbed for prototyping and validating new control room concepts. Equally importantly, it is helping create a standardized and vetted human factors engineering process that can be used across the nuclear industry to ensure control room upgrades maintain and even improve current reliability and safety.

  8. Poderes y Agencia: el resto es literatura / Proxy and Agency: the Rest is Literature

    Directory of Open Access Journals (Sweden)

    Katheen McNerney

    2011-01-01

    Full Text Available Resumen: De entre la gran multitud de emigrantes catalano-parlantes que llegó a la Cuba colonial, un cierto número de mujeres llegó a La Habana en busca de sus esposos, aquellos con los que se habían casado “por poderes” (poders justo antes de realizar el largo viaje. La obra de Carmen Riera Cap al cel obert narra la historia de las hermanas Fortesa, enviadas desde Mallorca. A Isabel la eligió su padre para casarla con un primo rico y se envió a María para acompañarla. Solamente María sobrevive el terrible viaje, que tiene lugar durante la última fase del control español sobre Cuba. Una vez en Cuba y recuperada de los avatares del viaje, María considera la vida monástica, pero en vez de ello, en su primera decisión real, acepta la oferta de matrimonio de Josep Fortalesa.El sistema de poderes continuó aun tras la independencia de Cuba del control de España en 1898 y esta forma de matrimonio conforma el tema de L’herència de Cuba de Margarida Aritzeta, en cuya portada se describe como “absolutament verídica”. Eugènia se casa con Basilio, un vecino de su pequeño pueblo aragonés cuando él, por medio de una carta y billete a la isla, manda que la traigan una vez instalado él allí después del viaje de 1925. Las dos novelas forman, de manera conjunta y a grandes rasgos, unos cien años de historia cubana, desde finales del siglo diecinueve hasta finales del siglo veinte, poniendo de relieve la lucha de mujeres que a menudo parecen arrastradas como hojas secas en un huracán, como diría Gertrudis Gómez de Avellaneda.

  9. UNIVERSITY TEACHING-LEARNING PROCESS: REFLECTIONS THROUGHOUT THE AGENCY THEORY EL PROCESO DE ENSEÑANZA-APRENDIZAJE UNIVERSITARIO: REFLEXIONES A TRAVÉS DE LA TEORÍA DE AGENCIA

    Directory of Open Access Journals (Sweden)

    Víctor Jacques Parraguez

    2011-03-01

    Full Text Available This work analyses some reasons that might explain the insufficient academic level which is perceived in universities of developing countries. The discussion element is the teacher-student relationship which is studied under the perspective of the agency theory. It is concluded that in absence of efficient monitoring mechanisms of the teacher and student’s behavior might proliferate gaps of due diligence which attempts against the quality of the teaching-learning process.En este trabajo se analizan algunas razones que pueden explicar el insuficiente nivel académico que se percibe en universidades de países en vías de desarrollo. El elemento de discusión es la relación profesor-alumno que es estudiada bajo el prisma de la teoría de agencia. Se concluye que en ausencia de eficientes mecanismos de control de la conducta tanto del profesor como del estudiante pueden proliferar vicios de responsabilidad que atentan contra la calidad del proceso de enseñanza-aprendizaje.

  10. REVIEW Of COMPUTERIZED PROCEDURE GUIDELINES FOR NUCLEAR POWER PLANT CONTROL ROOMS

    Energy Technology Data Exchange (ETDEWEB)

    David I Gertman; Katya Le Blanc; Ronald L Boring

    2011-09-01

    Computerized procedures (CPs) are recognized as an emerging alternative to paper-based procedures for supporting control room operators in nuclear power plants undergoing life extension and in the concept of operations for advanced reactor designs. CPs potentially reduce operator workload, yield increases in efficiency, and provide for greater resilience. Yet, CPs may also adversely impact human and plant performance if not designed and implemented properly. Therefore, it is important to ensure that existing guidance is sufficient to provide for proper implementation and monitoring of CPs. In this paper, human performance issues were identified based on a review of the behavioral science literature, research on computerized procedures in nuclear and other industries, and a review of industry experience with CPs. The review of human performance issues led to the identification of a number of technical gaps in available guidance sources. To address some of the gaps, we developed 13 supplemental guidelines to support design and safety. This paper presents these guidelines and the case for further research.

  11. Medical Image Processing Server applied to Quality Control of Nuclear Medicine.

    Science.gov (United States)

    Vergara, C.; Graffigna, J. P.; Marino, E.; Omati, S.; Holleywell, P.

    2016-04-01

    This paper is framed within the area of medical image processing and aims to present the process of installation, configuration and implementation of a processing server of medical images (MIPS) in the Fundación Escuela de Medicina Nuclear located in Mendoza, Argentina (FUESMEN). It has been developed in the Gabinete de Tecnologia Médica (GA.TE.ME), Facultad de Ingeniería-Universidad Nacional de San Juan. MIPS is a software that using the DICOM standard, can receive medical imaging studies of different modalities or viewing stations, then it executes algorithms and finally returns the results to other devices. To achieve the objectives previously mentioned, preliminary tests were conducted in the laboratory. More over, tools were remotely installed in clinical enviroment. The appropiate protocols for setting up and using them in different services were established once defined those suitable algorithms. Finally, it’s important to focus on the implementation and training that is provided in FUESMEN, using nuclear medicine quality control processes. Results on implementation are exposed in this work.

  12. Strategy for Migration of Traditional to Hybrid Control Boards in a Nuclear Power Plant

    Energy Technology Data Exchange (ETDEWEB)

    Boring, Ronald Laurids [Idaho National Lab. (INL), Idaho Falls, ID (United States); Joe, Jeffrey Clark [Idaho National Lab. (INL), Idaho Falls, ID (United States); Ulrich, Thomas Anthony [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2014-07-01

    This strategy document describes the NUREG-0711 based human factors engineering (HFE) phases and associated elements required to support design, verification and validation (V&V), and implementation of new digital control room elements in a legacy analog main control room (MCR). Information from previous planning and analysis work serves as the foundation for creating a human-machine interface (HMI) specification for distributed control systems (DCSs) to be implemented as part of nuclear power plant (NPP) modernization. This document reviews ways to take the HMSI specification and use it when migrating legacy displays or designing displays with new functionality. These displays undergo iterative usability testing during the design phase and then an integrated system validation (ISV) in the full-scope control room training simulator. Following successful demonstration of operator performance using the systems during the ISV, the new DCS is implemented at the plant, first in the training simulator and then in the MCR. This document concludes with a sample project plan, including a 15-month timeline from DCS design through implementation. Included is a discussion of how the U.S. Department of Energy’s Human System Simulation Laboratory (HSSL) can be used to support design and V&V activities. This report completes a Level 4 (M4) milestone under the U.S. Department of Energy’s (DOE’s) Light Water Reactor Sustainability (LWRS) Program.

  13. Psychological factors of professional success of nuclear power plant main control room operators

    Directory of Open Access Journals (Sweden)

    Kosenkov A.A.

    2014-12-01

    Full Text Available Aim: to conduct a comparative analysis of the psychological characteristics of the most and least successful main control room operators. Material and Methods. Two NPP staff groups: the most and least successful main control room operators, who worked in routine operating conditions, were surveyed. Expert evaluation method has been applied to identify the groups. The subjects were administered the Minnesota Multiphasic Personality Inventory (MMPI, Cattell's Sixteen Personality Factor Questionnaire (16PF form A and Raven's Progressive Matrices test. Results. Numerous significant psychological differences between the groups of most and least successful control room operators were obtained: the best operators were significantly more introverted and correctly solved more logical tasks with smaller percentage of mistakes under time pressure than worst ones. Conclusions: 1. The psychodiagnostic methods used in the study were adequate to meet research objective 2. Tendency to introversion, as well as developed the ability to solve logic problems undertime pressure, apparently, are important professional qualities for control room operators. These indicators should be considered in the process of psychological selection and professional guidance of nuclear power plant operators.

  14. ATCA/AXIe compatible board for fast control and data acquisition in nuclear fusion experiments

    Energy Technology Data Exchange (ETDEWEB)

    Batista, A.J.N., E-mail: toquim@ipfn.ist.utl.pt [Associacao EURATOM/IST, Instituto de Plasmas e Fusao Nuclear - Laboratorio Associado, Instituto Superior Tecnico - Universidade Tecnica de Lisboa, Lisboa (Portugal); Leong, C.; Bexiga, V. [INESC-ID, Lisboa (Portugal); Rodrigues, A.P.; Combo, A.; Carvalho, B.B.; Fortunato, J.; Correia, M. [Associacao EURATOM/IST, Instituto de Plasmas e Fusao Nuclear - Laboratorio Associado, Instituto Superior Tecnico - Universidade Tecnica de Lisboa, Lisboa (Portugal); Teixeira, J.P.; Teixeira, I.C. [INESC-ID, Lisboa (Portugal); Sousa, J.; Goncalves, B.; Varandas, C.A.F. [Associacao EURATOM/IST, Instituto de Plasmas e Fusao Nuclear - Laboratorio Associado, Instituto Superior Tecnico - Universidade Tecnica de Lisboa, Lisboa (Portugal)

    2012-12-15

    Highlights: Black-Right-Pointing-Pointer High performance board for fast control and data acquisition. Black-Right-Pointing-Pointer Large IO channel number per board with galvanic isolation. Black-Right-Pointing-Pointer Optimized for high reliability and availability. Black-Right-Pointing-Pointer Targeted for nuclear fusion experiments with long duration discharges. Black-Right-Pointing-Pointer To be used on the ITER Fast Plant System Controller prototype. - Abstract: An in-house development of an Advanced Telecommunications Computing Architecture (ATCA) board for fast control and data acquisition, with Input/Output (IO) processing capability, is presented. The architecture, compatible with the ATCA (PICMG 3.4) and ATCA eXtensions for Instrumentation (AXIe) specifications, comprises a passive Rear Transition Module (RTM) for IO connectivity to ease hot-swap maintenance and simultaneously to increase cabling life cycle. The board complies with ITER Fast Plant System Controller (FPSC) guidelines for rear IO connectivity and redundancy, in order to provide high levels of reliability and availability to the control and data acquisition systems of nuclear fusion devices with long duration plasma discharges. Simultaneously digitized data from all Analog to Digital Converters (ADC) of the board can be filtered/decimated in a Field Programmable Gate Array (FPGA), decreasing data throughput, increasing resolution, and sent through Peripheral Component Interconnect (PCI) Express to multi-core processors in the ATCA shelf hub slots. Concurrently the multi-core processors can update the board Digital to Analog Converters (DAC) in real-time. Full-duplex point-to-point communication links between all FPGAs, of peer boards inside the shelf, allow the implementation of distributed algorithms and Multi-Input Multi-Output (MIMO) systems. Support for several timing and synchronization solutions is also provided. Some key features are onboard ADC or DAC modules with galvanic isolation

  15. An innovative approach for Steam Generator Pressure Control of a nuclear power plant

    Energy Technology Data Exchange (ETDEWEB)

    Gaikwad, Avinash J., E-mail: avinashg@barc.gov.in [Reactor Safety Division, BARC, Trombay, Mumbai 400094 (India); Vijayan, P.K. [Reactor Engineering Divisions, BARC, Trombay, Mumbai 400094 (India); Bhartiya, Sharad [Chemical Engineering Departments, IIT, Powai, Mumbai (India); Kumar, Rajesh; Lele, H.G.; Vaze, K.K. [Reactor Safety Division, BARC, Trombay, Mumbai 400094 (India)

    2011-12-15

    Highlights: Black-Right-Pointing-Pointer Most of the transients/accidents have their origin in the mismatch among the heat generated in the reactor core and the heat removal in the SGs. Black-Right-Pointing-Pointer The main objective of balancing the heat generation, transfer and removal gets lost due to simplification of SGPC leading to reduced availability. Black-Right-Pointing-Pointer A new Advanced Process Control (APC) is proposed to ride over the existing SGPC to achieve the goal of prompt removal of the heat transfer mismatch. Black-Right-Pointing-Pointer The APC logic will lead to overall performance improvements and plant availability for all other transients also. - Abstract: The main function of the Steam Generator Pressure Control (SGPC) Program is to match the power (heat) generation in the reactor core with the heat removal in the steam generators (SGs). For most of the designs these programs have been over simplified to cater to the limitation of the instrumentation and control, hardware and software. The main objective of balancing the heat generation, transfer and removal gets lost in the process, which leads to reduction in the availability of the nuclear power plant. This is reflected in under utilization of the process and control system provisions to avoid reactor trips on low/high pressure. Most of the transients/accidents have their origin in the mismatch among the heat generated in the reactor core and the heat removal in the SGs. A new Advanced Process Control (APC) based supervisory controller is proposed to ride over the existing SGPC to achieve the goal. This APC makes use of the estimated/measured heat generation-removal error to alter the SGPC set point to tide over the transients after detection. The transients are detected based on the magnitude of this error to activate the APC. After tiding over the transient successfully the control switches back to the existing SGPC. For evaluation of this error additional instrumentation is

  16. Theoretical approaches to control spin dynamics in solid-state nuclear magnetic resonance

    Indian Academy of Sciences (India)

    Eugene Stephane Mananga

    2015-12-01

    This article reviews theoretical approaches for controlling spin dynamics in solid-state nuclear magnetic resonance. We present fundamental theories in the history of NMR, namely, the average Hamiltonian and Floquet theories. We also discuss emerging theories such as the Fer and Floquet-Magnus expansions. These theories allow one to solve the time-dependent Schrodinger equation, which is still the central problem in spin dynamics of solid-state NMR. Examples from the literature that highlight several applications of these theories are presented, and particular attention is paid to numerical integrators and propagator operators. The problem of time propagation calculated with Chebychev expansion and the future development of numerical directions with the Cayley transformation are considered. The bibliography includes 190 references.

  17. A Study of BUS Architecture Design for Controller of Nuclear Power Plant Using FPGA

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Dongil; Yun, Donghwa; Hwang, Sungjae; Kim, Myeongyun; Lee, Dongyun [PONUTech Co. Ltd., Seoul (Korea, Republic of)

    2014-05-15

    CPU (Central Processing Unit) operating speed and communication rate have been more technically improved than before. However, whole system is been a degradation of performance by electronic and structural limitation of parallel bus. Transmission quantity and speed have a limit and need arbiter in order to do arbitration because several boards shared parallel bus. Arbiter is a high complexity in implementing so it increases component per chip. If a parallel bus uses, it will occurs some problems what are reflection noise, power/ground noise (or ground bounce) as SSN (Simultaneous Switching Noise) and crosstalk noise like magnetic coupling. In this paper, in order to solve a problem of parallel bus in controller of NPP (Nuclear Power Plant), proposes the bus architecture design using FPGA (Field Programmable Gate Array) based on LVDS (Low Voltage Differential Signaling)

  18. Intelligent software system for the advanced control room of a nuclear power plant

    Energy Technology Data Exchange (ETDEWEB)

    Chang, Soon Heung; Choi, Seong Soo; Park, Jin Kyun; Heo, Gyung Young [Korea Advanced Institute of Science and Technology, Taejon (Korea, Republic of); Kim, Han Gon [Korea Electric Power Research Institute, Taejon (Korea, Republic of)

    1997-12-31

    The intelligent software system for nuclear power plants (NPPs) has been conceptually designed in this study. Its design goals are to operate NPPs in an improved manner and to support operators` cognitive takes. It consists of six major modules such as {sup I}nformation Processing,{sup {sup A}}larm Processing,{sup {sup P}}rocedure Tracking,{sup {sup P}}erformance Diagnosis,{sup a}nd {sup E}vent Diagnosis{sup m}odules for operators and {sup M}alfunction Diagnosis{sup m}odule for maintenance personnel. Most of the modules have been developed for several years and the others are under development. After the completion of development, they will be combined into one system that would be main parts of advanced control rooms in NPPs. 5 refs., 4 figs. (Author)

  19. Aging Management Guideline for commercial nuclear power plants: Motor control centers; Final report

    Energy Technology Data Exchange (ETDEWEB)

    Toman, G.; Gazdzinski, R.; O`Hearn, E. [Ogden Environmental and Energy Services Co., Inc., Blue Bell, PA (United States)

    1994-02-01

    This Aging Management Guideline (AMG) provides recommended methods for effective detection and mitigation of age-related degradation mechanisms in Boiling Water Reactor (BWR) and Pressurized Water Reactor (PWR) commercial nuclear power plant motor control centers important to license renewal. The intent of this AMG is to assist plant maintenance and operations personnel in maximizing the safe, useful life of these components. It also supports the documentation of effective aging management programs required under the License Renewal Rule 10 CFR Part 54. This AMG is presented in a manner that allows personnel responsible for performance analysis and maintenance to compare their plant-specific aging mechanisms (expected or already experienced) and aging management program activities to the more generic results and recommendations presented herein.

  20. Control and applications of cooperating disparate robotic manipulators relevant to nuclear waste management

    Science.gov (United States)

    Lew, Jae Young; Book, Wayne J.

    1991-01-01

    Remote handling in nuclear waste management requires a robotic system with precise motion as well as a large workspace. The concept of a small arm mounted on the end of a large arm may satisfy such needs. However, the performance of such a serial configuration lacks payload capacity which is a crucial factor for handling a massive object. Also, this configuration induces more flexibility on the structure. To overcome these problems, the topology of bracing the tip of the small arm (not the large arm) and having an end effector in the middle of the chain is proposed in this paper. Also, control of these cooperating disparate manipulators is accomplished in computer simulations. Thus, this robotic system can have the accuracy of the small arm, and at the same time, it can have the payload capacity and large workspace of the large arm.

  1. The impact of the instrumentation and control systems in the safety of a nuclear plant: a general vision; El impacto de los sistemas de instrumentacion y control en la seguridad de una planta nuclear: una vision general

    Energy Technology Data Exchange (ETDEWEB)

    Celis del Angel, L.; Rivero, T., E-mail: lina.celis@inin.gob.mx [ININ, Carretera Mexico-Toluca s/n, 52750 Ocoyoacac, Estado de Mexico (Mexico)

    2011-11-15

    One of the fundamental components so much for the sure operation, like in emergency cases or accident are the equipment s and instrumentation and control systems. The nuclear industry has had some accidents where the instrumentation and control have played and important part: a wrong design, instrumentation lack, faulty systems of safety, etc. At the present time the necessity to modernize the instrumentation and control in a nuclear power plant is before the challenge of finding innovative forms to improve the competitiveness and readiness, reducing operation costs without put ing in risk the safety and reliability of the nuclear power plant. Most of the nuclear power plants require actualizing their instrumentation and control systems, here the digital systems represent a great alternative, improving the performance and the safety, increasing the readiness and reducing the maintenance s. However they require of strict tests that allow assuring their application in critical systems. It is also necessary, the development of modernization programs that allow the programmed substitution of the systems without affecting the readiness of the nuclear power plants. During this whole modernization process will be necessary to put special attention in the cyber-safety because the attacks every time they are more elaborated. Therefore will be necessary to go toward the modernization of the instrumentation and control with the challenge of making without detriment some in the safety of the normal operation and with response reliability in emergency conditions or accident that which represents an effort that should not be postponed in the case of the nuclear power plant of Laguna Verde. (Author)

  2. Virus-Induced Chaperone-Enriched (VICE domains function as nuclear protein quality control centers during HSV-1 infection.

    Directory of Open Access Journals (Sweden)

    Christine M Livingston

    2009-10-01

    Full Text Available Virus-Induced Chaperone-Enriched (VICE domains form adjacent to nuclear viral replication compartments (RC during the early stages of HSV-1 infection. Between 2 and 3 hours post infection at a MOI of 10, host protein quality control machinery such as molecular chaperones (e.g. Hsc70, the 20S proteasome and ubiquitin are reorganized from a diffuse nuclear distribution pattern to sequestration in VICE domains. The observation that VICE domains contain putative misfolded proteins suggests that they may be similar to nuclear inclusion bodies that form under conditions in which the protein quality control machinery is overwhelmed by the presence of misfolded proteins. The detection of Hsc70 in VICE domains, but not in nuclear inclusion bodies, indicates that Hsc70 is specifically reorganized by HSV-1 infection. We hypothesize that HSV-1 infection induces the formation of nuclear protein quality control centers to remodel or degrade aberrant nuclear proteins that would otherwise interfere with productive infection. Detection of proteolytic activity in VICE domains suggests that substrates may be degraded by the 20S proteasome in VICE domains. FRAP analysis reveals that GFP-Hsc70 is dynamically associated with VICE domains, suggesting a role for Hsc70 in scanning the infected nucleus for misfolded proteins. During 42 degrees C heat shock, Hsc70 is redistributed from VICE domains into RC perhaps to remodel viral replication and regulatory proteins that have become insoluble in these compartments. The experiments presented in this paper suggest that VICE domains are nuclear protein quality control centers that are modified by HSV-1 to promote productive infection.

  3. International training course on implementation of state systems of accounting for and control of nuclear materials: proceedings

    Energy Technology Data Exchange (ETDEWEB)

    1984-06-01

    This report incorporates all lectures and presentations at the International Training Course on Implementation of State Systems of Accounting for and Control of Nuclear Materials held October 17 through November 4, 1983, at Santa Fe and Los Alamos, New Mexico and Richland, Washington, USA. Authorized by the US Nuclear Non-Proliferation Act and sponsored by the US Department of Energy in cooperation with the International Atomic Energy Agency, the course was developed to provide practical training in the design, implementation, and operation of a State system of nuclear materials accountability and control that satisfies both national and international safeguards requirements. Major emphasis for the 1983 course was placed on safeguards methods used at bulk-handling facilities, particularly low-enriched uranium conversion and fuel fabrication plants. The course was conducted by the University of California's Los Alamos National Laboratory and Exxon Nuclear Company, Inc. Tours and demonstrations were arranged at the Los Alamos National Laboratory, Los Alamos, New Mexico, and the Exxon Nuclear fuel fabrication plant, the Battelle Pacific Northwest Laboratory, Westinghouse Fast Flux Test Facility Visitor Center, and Washington Public Power System nuclear reactor facilities in Richland, Washington. Individual presentations were indexed for inclusion in the Energy Data Base.

  4. The Programmable Logic Controller and its application in nuclear reactor systems

    Energy Technology Data Exchange (ETDEWEB)

    Palomar, J.; Wyman, R. [Lawrence Livermore National Lab., CA (United States)

    1993-09-01

    This document provides recommendations to guide reviewers in the application of Programmable Logic Controllers (PLCS) to the control, monitoring and protection of nuclear reactors. The first topics addressed are system-level design issues, specifically including safety. The document then discusses concerns about the PLC manufacturing organization and the protection system engineering organization. Supplementing this document are two appendices. Appendix A summarizes PLC characteristics. Specifically addressed are those characteristics that make the PLC more suitable for emergency shutdown systems than other electrical/electronic-based systems, as well as characteristics that improve reliability of a system. Also covered are PLC characteristics that may create an unsafe operating environment. Appendix B provides an overview of the use of programmable logic controllers in emergency shutdown systems. The intent is to familiarize the reader with the design, development, test, and maintenance phases of applying a PLC to an ESD system. Each phase is described in detail and information pertinent to the application of a PLC is pointed out.

  5. The Quantometer as an analytical instrument in the control of nuclear materials; El cuantometro como instrumento analitico en el control de materiales nucleares

    Energy Technology Data Exchange (ETDEWEB)

    Alvarez Gonzalez, F.; Roca Adell, M.; Fernandez Cellini, R.

    1961-07-01

    In order to solve different problems of chemical analysis in the fields of nuclear industry and research, a Quantometer is used with a high number of channels. A detailed study to choose the more suitable spectral lines is described. The different channels have been distributed into two programs to allow the analysis of high and low concentrations. The Quantometer is being applied successfully to analyse soils, plant ashes, rocks and ores, uranium and its compounds, zirconium, graphite, alloys and other nuclear materials. (Author) 6 refs.

  6. Agencia de autocuidado y factores básicos condicionantes en adultos mayores Autocuidado e fatores básicos condicionantes em adultos maiores Self-care agency and basic conditioning factors in the elderly

    OpenAIRE

    Alba Rosa Fernández; Fred Gustavo Manrique-Abril

    2011-01-01

    La agencia de autocuidado es la capacidad que posee un individuo para cuidar de sí mismo; en ella pueden influir unos elementos que son propios de la persona o del ambiente en que vive, llamados factores básicos condicionantes. Objetivo: determinar la agencia de autocuidado y los factores básicos condicionantes en adultos mayores con hipertensión arterial, de Tunja, Boyacá, Colombia. Metodología: estudio descriptivo, de corte transversal, con 240 adultos mayores, realizado en julio de 2009. S...

  7. Las relaciones públicas ante el reto digital y el fenómeno Twiter: estudio sobre la respuesta de las agencias de RRPP y del subsector empresarial de las bebidas fermentadas en España

    OpenAIRE

    Fernández Muñoz, Cristóbal

    2012-01-01

    El principal objetivo marcado en este trabajo de investigación es el de profundizar en el conocimiento del impacto que la comunicación digital está teniendo entre los practicantes de las Relaciones Públicas en España en el ámbito de las agencias de servicios profesionales y de un subsector empresarial español, en este caso el de las bebidas fermentas, como muestra del universo corporativo en nuestro país. Las agencias de RR.PP. y los departamentos de comunicación de las organizaciones del sec...

  8. Agencias sociales: una estrategia de gestión, apropiación de políticas públicas e inclusión social en comunidades indígenas wayuu

    OpenAIRE

    2016-01-01

    Para lograr que las comunidades indígenas wayuu, con su rezago social, se apropien de los beneficios de las políticas públicas en Colombia, el grupo de investigación Contacto con la comunidad, auspiciado por la Universidad de la Guajira, ha creado y desarrollado un concepto estratégico denominado agencias sociales. Estas agencias son un agente colectivo mediador intencional entre las comunidades, las instituciones públicas y el centro de conocimiento o academia, para la apropiación de las pol...

  9. La comunicación como proceso de construcción de ciudadanía y de agencia política en los colectivos juveniles

    Directory of Open Access Journals (Sweden)

    Daniel Valencia Nieto

    2010-01-01

    Full Text Available Este artículo se ocupa de describir los hallazgos del proyecto de investigación sobre las prácticas juveniles como expresiones ciudadanas. Desde la relación comunicación/ política, el artículo da cuenta de cómo se pueden identificar los procesos de construcción de la agencia política de los colectivos juveniles. Se ocupa de analizar, a partir de los modelos de organización, de las acciones emprendidas y de las formas de comunicación, cómo los miembros de los grupos juveniles intentan generar un tipo de agencia política para las reivindicaciones sociales que demandan mediante la acción colectiva. Finalmente, el artículo se ocupa de describir cómo, por medio de los procesos de comunicación, se hace visible la amplitud y la diversidad de los ejercicios ciudadanos de los jóvenes. Llama la atención sobre los problemas y dificultades que enfrentan estos grupos en cuanto a su latencia y permanencia en la vida política, a la vez que destaca el potencial formativo de dichas prácticas.

  10. El uso de la información de agencia en las ediciones electrónicas de diarios en España

    Directory of Open Access Journals (Sweden)

    David Sancha

    2005-11-01

    Full Text Available Los diarios de información general disponen en Internet de servicios de información on line actualizados permanentemente, que tienen en las agencias de noticias su fuente informativa fundamental. La urgencia por la publicación y la necesidad de llevar a cabo una actualización acumulativa lleva a una reelaboración mínima de los despachos que sirven las agencias y genera una homogeneización de los contenidos que se publican en los servicios on line de los distintos diarios. La presente investigación aborda mediante datos estadísticos, análisis de casos y entrevistas cómo los matices editoriales de cada publicación se diluyen en la redacción de las noticias y cada medio se ve obligado a buscar nuevos elementos informativos donde imprimir su carácter ideológico y diferenciar su producto de la competencia.

  11. Visualization of the network of primo vessels and primo nodes above the pia mater of the brain and spine of rats by using Alcian blue.

    Science.gov (United States)

    Lee, Ho-Sung; Lee, Byung-Cheon

    2012-10-01

    By spraying and injecting Alcian blue into the lateral ventricle, we were able to visualize the network of the nerve primo vascular system above the pia mater of the brain and spine of rats. Staining these novel structures above the pia mater with 4',6-diamidino-2-phenylindole demonstrated that they coexisted in cellular and extracellular DNA forms. The cellular primo node consisted of many cells surrounded by rod-shaped nuclei while the extracellular primo node had a different morphology from that of a general cell in terms of DNA signals, showing granular DNA in a threadlike network of extracellular DNA. Also, differently from F-actin in general cells, the F-actin in the primo vessel was short and rod-shaped. Light and transmission electron microscopic images of the PN showed that the nerve primo vascular system above the pia mater of the brain and spine was a novel dynamic network, suggesting the coexistence of DNA and extracellular DNA. Based on these data, we suggest that a novel dynamic system with a certain function exists above the pia mater of the central nerve system. We also discuss the potential of this novel network system in the brain and spine as related to acupuncture meridians and neural regeneration.

  12. International training course on implementation of state systems of accounting for and control of nuclear materials: proceedings

    Energy Technology Data Exchange (ETDEWEB)

    1986-06-01

    This report incorporates all lectures and presentations at the International Training Course on Implementation of State Systems of Accounting for and Control of Nuclear Materials held June 3 through June 21, 1985, at Santa Fe and Los Alamos, New Mexico, and San Clemente, California. Authorized by the US Nuclear Non-Proliferation Act and sponsored by the US Department of Energy in cooperation with the International Atomic Energy Agency, the Course was developed to provide practical training in the design, implementation, and operation of a state system of nuclear materials accountability and control that satisfies both national and international safeguards requirements. Major emphasis for the 1985 course was placed on safeguards methods used at item-control facilities, particularly nuclear power generating stations and test reactors. An introduction to safeguards methods used at bulk handling facilities, particularly low-enriched uranium conversion and fuel fabrication plants, was also included. The course was conducted by the University of California's Los Alamos National Laboratory and the Southern California Edison Company. Tours and demonstrations were arranged at the Los Alamos National Laboratory, Los Alamos, New Mexico, and the San Onofre Nuclear Generating Station, San Clemente, California.

  13. Nuclear Rocket Facility Decommissioning Project: Controlled Explosive Demolition of Neutron-Activated Shield Wall

    Energy Technology Data Exchange (ETDEWEB)

    Michael R. Kruzic

    2008-06-01

    Located in Area 25 of the Nevada Test Site (NTS), the Test Cell A (TCA) Facility (Figure 1) was used in the early to mid-1960s for testing of nuclear rocket engines, as part of the Nuclear Rocket Development Program, to further space travel. Nuclear rocket testing resulted in the activation of materials around the reactors and the release of fission products and fuel particles. The TCA facility, known as Corrective Action Unit 115, was decontaminated and decommissioned (D&D) from December 2004 to July 2005 using the Streamlined Approach for Environmental Restoration (SAFER) process, under the Federal Facility Agreement and Consent Order. The SAFER process allows environmental remediation and facility closure activities (i.e., decommissioning) to occur simultaneously, provided technical decisions are made by an experienced decision maker within the site conceptual site model. Facility closure involved a seven-step decommissioning strategy. First, preliminary investigation activities were performed, including review of process knowledge documentation, targeted facility radiological and hazardous material surveys, concrete core drilling and analysis, shield wall radiological characterization, and discrete sampling, which proved to be very useful and cost-effective in subsequent decommissioning planning and execution and worker safety. Second, site setup and mobilization of equipment and personnel were completed. Third, early removal of hazardous materials, including asbestos, lead, cadmium, and oil, was performed ensuring worker safety during more invasive demolition activities. Process piping was to be verified void of contents. Electrical systems were de-energized and other systems were rendered free of residual energy. Fourth, areas of high radiological contamination were decontaminated using multiple methods. Contamination levels varied across the facility. Fixed beta/gamma contamination levels ranged up to 2 million disintegrations per minute (dpm)/100

  14. Standard guide for application of radiation monitors to the control and physical security of special nuclear material

    CERN Document Server

    American Society for Testing and Materials. Philadelphia

    1999-01-01

    1.1 This guide briefly describes the state-of-the-art of radiation monitors for detecting special nuclear material (SNM) (see 3.1.11) in order to establish the context in which to write performance standards for the monitors. This guide extracts information from technical documentation to provide information for selecting, calibrating, testing, and operating such radiation monitors when they are used for the control and protection of SNM. This guide offers an unobtrusive means of searching pedestrians, packages, and motor vehicles for concealed SNM as one part of a nuclear material control or security plan for nuclear materials. The radiation monitors can provide an efficient, sensitive, and reliable means of detecting the theft of small quantities of SNM while maintaining a low likelihood of nuisance alarms. 1.2 Dependable operation of SNM radiation monitors rests on selecting appropriate monitors for the task, operating them in a hospitable environment, and conducting an effective program to test, calibrat...

  15. Fine control of nuclear confinement identifies a threshold deformation leading to lamina rupture and induction of specific genes.

    Science.gov (United States)

    Le Berre, Maël; Aubertin, Johannes; Piel, Matthieu

    2012-11-01

    The quest to understand how the mechanical and geometrical environment of cells impacts their behavior and fate has been a major force driving the recent development of new technologies in cell biology research. Despite rapid advances in this field, many challenges remain in order to bridge the gap between the classical and simple cell culture plate and the biological reality of actual tissue. In tissues, cells have their physical space constrained by neighboring cells and the extracellular matrix. Here, we propose a simple and versatile device to precisely and dynamically control this confinement parameter in cultured cells. We show that there is a precise threshold deformation above which the nuclear lamina breaks and reconstructs, whereas nuclear volume changes. We also show that different nuclear deformations correlate with the expression of specific sets of genes, including nuclear factors and classical mechanotransduction pathways. This versatile device thus enables the precise control of cell and nuclear deformation by confinement and the correlative study of the associated molecular events.

  16. Dynamical nuclear polarization using multi-colour control of color centers in diamond

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Pengcheng [Huazhong University of Science and Technology, School of Physics, Wuhan (China); Huazhong University of Science and Technology, Center for Quantum Optical Science, Wuhan (China); Plenio, Martin B. [Universitaet Ulm, Institut fuer Theoretische Physik, Ulm (Germany); Universitaet Ulm, Center for Integrated Quantum Science and Technology, Ulm (Germany); Cai, Jianming [Huazhong University of Science and Technology, School of Physics, Wuhan (China); Huazhong University of Science and Technology, Center for Quantum Optical Science, Wuhan (China); Universitaet Ulm, Institut fuer Theoretische Physik, Ulm (Germany); Universitaet Ulm, Center for Integrated Quantum Science and Technology, Ulm (Germany)

    2016-12-15

    Dynamical nuclear polarization (DNP) transfers the polarization of electron spins at cryogenic temperatures to achieve strong nuclear polarization for applications in nuclear magnetic resonance. Recently introduced approaches employ optical pumping of nitrogen-vacancy (NV) centers in diamond to achieve DNP even at ambient temperatures. In such schemes microwave radiation is used to establish a Hartmann-Hahn condition between the NV electron spin and proximal nuclear spins to facilitate polarization transfer. For a single monochromatic microwave driving field, the Hartmann-Hahn condition cannot be satisfied for an ensemble of NV centers due to inhomogeneous broadening and reduces significantly the overall efficiency of dynamical nuclear polarization using an ensemble of NV centers. Here, we adopt generalized Hartmann-Hahn type dynamical nuclear polarization schemes by applying microwave driving fields with (multiple) time-modulated frequencies. We show that it is possible to enhance the effective coupling between an ensemble of NV center spins with inhomogeneous broadening and nuclear spins, thereby improving significantly the overall efficiency of dynamical nuclear polarization. This approach can also be used to achieve dynamical nuclear polarization of an ensemble of nuclei with a distribution of Larmor frequencies, which would be helpful in magnetic resonance spectroscopy using a single NV spin sensor. (orig.)

  17. Control of multiscale systems with constraints. 2. Fractal nuclear isomers and clusters

    CERN Document Server

    Adamenko, S; Novikov, V

    2013-01-01

    We consider the influence of the Fermi statistics of nucleons on the binding energy of a new type of nuclear structures such as fractal nuclear clusters (fractal isomers of nuclei). It is shown that the fractal nuclear isomers possess a wide spectrum of binding energies that exceed, in many cases, the values known at the present time. The transition of the nuclear matter in the form of ordinary nuclei (drops of the nuclear fluid) in the state with the fractal structure or in the form of bubble nuclei opens new sources of energy and has huge perspectives. This transition is based on a new state of matter - collective coherently correlated state. It manifests itself, first of all, in the property of nonlocality of nuclear multiparticle processes. We develop a phenomenological theory of the binding energy of nuclear fractal structures and modify the Bethe - Weizs\\"acker formula for nuclear clusters with the mass number A, charge Z, and fractal dimension D_f. The consideration of fractal nuclear isomers allows on...

  18. An agonist–antagonist cerebellar nuclear system controlling eyelid kinematics during motor learning

    Directory of Open Access Journals (Sweden)

    Raudel eSánchez-Campusano

    2012-03-01

    Full Text Available The presence of two antagonistic groups of deep cerebellar nuclei neurons has been reported as necessary for a proper dynamic control of learned motor responses. Most models of cerebellar function seem to ignore the biomechanical need for a double activation–deactivation system controlling eyelid kinematics, since most of them accept that, for closing the eyelid, only the activation of the orbicularis oculi muscle (via the red nucleus to the facial motor nucleus is necessary, without a simultaneous deactivation of levator palpebrae motoneurons (via unknown pathways projecting to the perioculomotor area. We have analyzed the kinetic neural commands of two antagonistic types of cerebellar posterior interpositus neuron (types A and B, the electromyographic activity of the orbicularis oculi muscle, and eyelid kinematic variables in alert behaving cats during classical eyeblink conditioning, using a delay paradigm. We addressed the hypothesis that the interpositus nucleus can be considered an agonist–antagonist system controlling eyelid kinematics during motor learning. To carry out a comparative study of the kinetic–kinematic relationships, we applied timing and dispersion pattern analyses. We concluded that, in accordance with a dominant role of cerebellar circuits for the facilitation of flexor responses, type A neurons fire during active eyelid downward displacements ─ i.e., during the active contraction of the orbicularis oculi muscle. In contrast, type B neurons present a high tonic rate when the eyelids are wide open, and stop firing during any active downward displacement of the upper eyelid. From a functional point of view, it could be suggested that type B neurons play a facilitative role for the antagonistic action of the levator palpebrae muscle. From an anatomical point of view, the possibility that cerebellar nuclear type B neurons project to the perioculomotor area ─ i.e., more or less directly onto levator palpebrae

  19. On a distinctive feature of problems of calculating time-average characteristics of nuclear reactor optimal control sets

    Science.gov (United States)

    Trifonenkov, A. V.; Trifonenkov, V. P.

    2017-01-01

    This article deals with a feature of problems of calculating time-average characteristics of nuclear reactor optimal control sets. The operation of a nuclear reactor during threatened period is considered. The optimal control search problem is analysed. The xenon poisoning causes limitations on the variety of statements of the problem of calculating time-average characteristics of a set of optimal reactor power off controls. The level of xenon poisoning is limited. There is a problem of choosing an appropriate segment of the time axis to ensure that optimal control problem is consistent. Two procedures of estimation of the duration of this segment are considered. Two estimations as functions of the xenon limitation were plot. Boundaries of the interval of averaging are defined more precisely.

  20. A Pilot Study Investigating the Effects of Advanced Nuclear Power Plant Control Room Technologies: Methods and Qualitative Results

    Energy Technology Data Exchange (ETDEWEB)

    BLanc, Katya Le [Idaho National Lab. (INL), Idaho Falls, ID (United States); Powers, David [Idaho National Lab. (INL), Idaho Falls, ID (United States); Joe, Jeffrey [Idaho National Lab. (INL), Idaho Falls, ID (United States); Spielman, Zachary [Idaho National Lab. (INL), Idaho Falls, ID (United States); Rice, Brandon [Idaho National Lab. (INL), Idaho Falls, ID (United States); Fitzgerald, Kirk [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2015-08-01

    Control room modernization is an important part of life extension for the existing light water reactor fleet. None of the 99 currently operating commercial nuclear power plants in the U.S. has completed a full-scale control room modernization to date. Nuclear power plant main control rooms for the existing commercial reactor fleet remain significantly analog, with only limited digital modernizations. Upgrades in the U.S. do not achieve the full potential of newer technologies that might otherwise enhance plant and operator performance. The goal of the control room upgrade benefits research is to identify previously overlooked benefits of modernization, identify candidate technologies that may facilitate such benefits, and demonstrate these technologies through human factors research. This report describes a pilot study to test upgrades to the Human Systems Simulation Laboratory at INL.

  1. Quality control for the equipment of Nuclear medicine: experience of the H.U. de la Princesa; Control de calidad del equipamiento en Medicina Nuclear. Experiencia enel H.U. de la Princesa

    Energy Technology Data Exchange (ETDEWEB)

    Espana, M.L.; Gracia, A.; Prieto, C.; Lopez F, P. [Servicio de ProteccionRadiologica. Hospital Universitario de la Princesa C/ Diego de Leon 62, 28006Madrid (Spain)

    1998-12-31

    The quality control of the equipment used in a nuclear medicine service is a fundamental aspect in the Quality Assurance Program that in the present time is starting in our hospital. the objective of this work is to present the internal protocol used, its problematic associated with its starting, and the results obtained in the quality control as of the gamma camera as of the activimeter. In addition to the equipment own to the nuclear medicine service it has been used a Cs-137 source and puppets for several purposes. The results obtained demonstrated the stability of the controlled parameters which has led us to a restating of the established periodicities in our internal protocol, over all for some constancy tests. (Author)

  2. Physical Mechanisms and Feedback Control of Beam Halo-Chaos for Accelerator-driven Radioactive-clean Nuclear Power Systems

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    High-current proton beams have attractive features for possible breakthrough applications, especially for accelerator-driven radioactive-clean nuclear power systems (ADS), which make nuclear energy systems safer, cleaner, cheaper, and therefore more practical. However, beam halo-chaos in ADS has become one of the key technical issues because it can cause excessive radio-activation from the accelerators and significantly limits the industrial applications of the new accelerators.Some general engineering methods for chaos control have been developed, but they generally

  3. Applications of Kalman Filtering to nuclear material control. [Kalman filtering and linear smoothing for detecting nuclear material losses

    Energy Technology Data Exchange (ETDEWEB)

    Pike, D.H.; Morrison, G.W.; Westley, G.W.

    1977-10-01

    The feasibility of using modern state estimation techniques (specifically Kalman Filtering and Linear Smoothing) to detect losses of material from material balance areas is evaluated. It is shown that state estimation techniques are not only feasible but in most situations are superior to existing methods of analysis. The various techniques compared include Kalman Filtering, linear smoothing, standard control charts, and average cumulative summation (CUSUM) charts. Analysis results indicated that the standard control chart is the least effective method for detecting regularly occurring losses. An improvement in the detection capability over the standard control chart can be realized by use of the CUSUM chart. Even more sensitivity in the ability to detect losses can be realized by use of the Kalman Filter and the linear smoother. It was found that the error-covariance matrix can be used to establish limits of error for state estimates. It is shown that state estimation techniques represent a feasible and desirable method of theft detection. The technique is usually more sensitive than the CUSUM chart in detecting losses. One kind of loss which is difficult to detect using state estimation techniques is a single isolated loss. State estimation procedures are predicated on dynamic models and are well-suited for detecting losses which occur regularly over several accounting periods. A single isolated loss does not conform to this basic assumption and is more difficult to detect.

  4. On the Future of Global Nuclear Arms Control and Disarmament Process

    Institute of Scientific and Technical Information of China (English)

    Shi Jianbin; Zhu Jianyu

    2016-01-01

    Because of the amazing destructions and great damages,nuclear weapons have been the objects the international community devotes itself to restrict and eliminate since their emergence.Compared to the height of the Cold War,although currently the size of the U.S.and Russian nuclear arsenals have been greatly

  5. Initial Position, Personal Control, and Attributional Augmentation of Persuasive Communication on Nuclear Disarmament.

    Science.gov (United States)

    Fleming, John H.; Shaver, Kelly G.

    The effectiveness of two alternative attitude change strategies--a traditional persuasive strategy and a combined attributional/persuasive strategy--in altering attitudes toward nuclear disarmament were compared. Seventeen male and 39 female undergraduate students at a small university participated. A nuclear disarmament attitude pretest was…

  6. Reliability centered maintenance applied to the control rod drives of a nuclear power reactor

    Energy Technology Data Exchange (ETDEWEB)

    Lyytikaeinen, A.; Holmberg, J. (Technical Research Centre of Finland, Espoo (Finland)); Unga, E. (Teollisuuden Voima Oy, Olkiluoto (Finland))

    1990-12-01

    Reliability Centered Maintenance (RCM) offers a hybrid reliability analysis methodology to evaluate the level of maintenance and direct the resources in an effective manner. The RCM analysis consists of several steps, including a Logic Tree Analysis (LTA) for identification of applicable and efficient preventive maintenance task. As a result of the analysis the total amount of maintenance of equipment is decreased or increased, depending on whether the failures are potential having adverse effects on plant safety, availability or economics. A RCM analysis results thus in an improved preventive maintenance program, which is supposed to decrease the maintenance and outage costs and at the same time increase the system safety and reliability. A problem is the relatively large and slow analysis effort, the fact which tends to inhibit the large scale and continuous application of this useful method. A case study is described, in which the control rod equipment at the TVO I/II nuclear units was analyzed and the problematics of the RCM-method is discussed. (au).

  7. Control of in vivo (cellular) phleomycin sensitivity by nuclear genotype, growth phase, and metal ions

    Energy Technology Data Exchange (ETDEWEB)

    Moore, C.W.

    1982-03-01

    Nuclear genotype, growth phase, and the presence of metal ions all proved to be important in controlling the lethal effects of phleomycin in eukaryotic Saccharomyces cerevisiae. Among 120 normal and radiation-sensitive strains compared for their sensitivities to lethal effects of phleomycin, all mutant strains exhibiting enhanced sensitivities to phleomycin killing were also sensitive to killing by ionizing radiation. Mutants exhibiting sensitivities to phleomycin similar to normal strains of the same ploidy were sensitive to ultraviolet radiation. We conclude that cellular recovery from phleomycin-induced damage in yeast depends upon the function of some or all of 13 independent genes and upon at least some of the same steps in cellular pathways for the biological repair of damage by ionizing radiation. In this respect, the action of phleomycin is similar to the action of its structurally similar analog, bleomycin, even though phleomycin was substantially more cytotoxic. Stationary-phase haploid yeast cells were more sensitive than exponentially growing cells to killing by phleomycin. Survival of stationary-phase yeast was reduced to 0.3 +/- 0.07% (S.E.) after 20-min exposures to phleomycin (1 microgram/ml; approximately 6.7 x 10(-7) M), but lethal effects of phleomycin were completely eradicated (98% survival) by the presence of 0.05 M ethylenediaminetetraacetate during the treatment period. The inactivation indicates an important role for one or more metal ion(s) in the in vivo toxicity of the phleomycin-bleomycin group of anticancer antibiotics.

  8. Delegation, Presidential Regimes, and Latin American Regulatory Agencies Delegación, regimenes presidenciales y agencias reguladoras en América Latina

    Directory of Open Access Journals (Sweden)

    Jacint Jordana

    2010-04-01

    Full Text Available During the 1990s, a large number of regulatory agencies were created or reformed in different sectors in Latin American countries. Almost all included political delegation mechanisms, intended as formal rules to enhance credible commitments to time-consistent policies. In this paper, using an original data set of agencies’ head tenure in the telecommunications and finance regulatory agencies, we discuss if these mechanisms worked as planned, and find a divergence between actual mandates and the formally established fixed terms, effected by means of systematic early resignations. Our findings reveal, however, some consistent patterns of behavior. Stronger legislative presidential power reduced effective delegation to some extent, and agencies’ organizational strengths protected them from patron-age. We also confirmed the existence of some significant differences be-tween the two sectors examined. Having slightly weaker delegation rules, delegation practices were also less effective in telecommunications than in financial services, contrary to expectations about credible commitments. Durante los años 1990, muchas agencias reguladoras fueron creadas o reformadas en diferentes sectores en los países latinoamericanos. Casi todas incluyeron mecanismos de delegación política, entendidos como reglas formales para mejorar los compromisos creíbles sobre políticas que requieren coherencia en el tiempo. En este trabajo, utilizando un conjunto de datos originales sobre los responsables de las agencias reguladoras de las telecomunicaciones y de las finanzas, se discute si estos mecanismos funcionaron como estaba previsto, identificándose una divergencia entre los mandatos reales y los términos formalmente establecidos, debido a la existencia de numerosas renuncias anticipadas. Nuestros hallazgos revelan, sin embargo, algunos patrones consistentes de comportamiento: un mayor poder presidencial sobre el legislativo reduce la delegación efectiva

  9. DOE/DHS INDUSTRIAL CONTROL SYSTEM CYBER SECURITY PROGRAMS: A MODEL FOR USE IN NUCLEAR FACILITY SAFEGUARDS AND SECURITY

    Energy Technology Data Exchange (ETDEWEB)

    Robert S. Anderson; Mark Schanfein; Trond Bjornard; Paul Moskowitz

    2011-07-01

    Many critical infrastructure sectors have been investigating cyber security issues for several years especially with the help of two primary government programs. The U.S. Department of Energy (DOE) National SCADA Test Bed and the U.S. Department of Homeland Security (DHS) Control Systems Security Program have both implemented activities aimed at securing the industrial control systems that operate the North American electric grid along with several other critical infrastructure sectors (ICS). These programs have spent the last seven years working with industry including asset owners, educational institutions, standards and regulating bodies, and control system vendors. The programs common mission is to provide outreach, identification of cyber vulnerabilities to ICS and mitigation strategies to enhance security postures. The success of these programs indicates that a similar approach can be successfully translated into other sectors including nuclear operations, safeguards, and security. The industry regulating bodies have included cyber security requirements and in some cases, have incorporated sets of standards with penalties for non-compliance such as the North American Electric Reliability Corporation Critical Infrastructure Protection standards. These DOE and DHS programs that address security improvements by both suppliers and end users provide an excellent model for nuclear facility personnel concerned with safeguards and security cyber vulnerabilities and countermeasures. It is not a stretch to imagine complete surreptitious collapse of protection against the removal of nuclear material or even initiation of a criticality event as witnessed at Three Mile Island or Chernobyl in a nuclear ICS inadequately protected against the cyber threat.

  10. Radiological controls and worker and public health and safety: An independent safety assessment of Department of Energy nuclear reactor facilities

    Energy Technology Data Exchange (ETDEWEB)

    Tew, J.L.; Miles, M.E.; Knuth, D.; Boyd, R.

    1981-02-01

    DOE has formed a Nuclear Facilities Personnel Qualification and Training (NFPQT) Committee to assess the implications of the Report of the President's Commission on the Accident at Three Mile Island that are applicable to DOE's nuclear reactor operations. Thirteen DOE nuclear reactors were reviewed by the Committee. This report was prepared to provide a measure of how the radiological control and environmental practices at the 13 individual DOE reactor facilities measure up to (1) the recommendations contained in the Report of the President's Commission on the Accident at Three Mile Island, (2) the requirements and guidelines contained, and (3) the requirements of the applicable Title and Part of the Code of Federal Regulations.

  11. Modification and updating of documentation in equipment of panels of control room in nuclear power plant operation; Modificacion y actualizacion de documentacion en aparatos de paneles de sala de control en una central nuclear en operacion

    Energy Technology Data Exchange (ETDEWEB)

    Agudo Montero, L.

    2013-07-01

    The present paper describes a case very unique specific design of interactive 2D-CAD application, that has been developed by Empresarios Agrupados as engineering support to the nuclear power plants, aware of the problem that exists with the documentation of the instruments and devices that are on the panels of Control room, and that only have the documentation generated in its day by the manufacturers of these panels. To this end, an application (application DOPAB) has been developed to help solve the problem of management, design and modification of wiring and wiring devices existing in the Control room control panels.

  12. Heat Transfer Salts for Nuclear Reactor Systems - Chemistry Control, Corrosion Mitigation, and Modeling

    Energy Technology Data Exchange (ETDEWEB)

    Anderson, Mark [Univ. of Wisconsin, Madison, WI (United States); Sridharan, Kumar [Univ. of Wisconsin, Madison, WI (United States); Morgan, Dane [Univ. of Wisconsin, Madison, WI (United States); Peterson, Per [Univ. of Wisconsin, Madison, WI (United States); Calderoni, Pattrick [Univ. of Wisconsin, Madison, WI (United States); Scheele, Randall [Univ. of Wisconsin, Madison, WI (United States); Casekka, Andrew [Univ. of Wisconsin, Madison, WI (United States); McNamara, Bruce [Univ. of Wisconsin, Madison, WI (United States)

    2015-01-22

    The concept of a molten salt reactor has existed for nearly sixty years. Previously all work was done during a large collaborative effort at Oak Ridge National Laboratory, culminating in a research reactor which operated for 15,000 hours without major error. This technical success has garnished interest in modern, high temperature, reactor schemes. Research using molten fluoride salts for nuclear applications requires a steady supply of high grade molten salts. There is no bulk supplier of research grade fluoride salts in the world, so a facility which could provide all the salt needed for testing at the University of Wisconsin had to be produced. Two salt purification devices were made for this purpose, a large scale purifier, and a small scale purifier, each designed to clean the salts from impurities and reduce their corrosion potential. As of now, the small scale has performed with flibe salt, hydrogen, and hydrogen fluoride, yielding clean salt. This salt is currently being used in corrosion testing facilities at the Massachusetts Institute of Technology and the University of Wisconsin. Working with the beryllium based salts requires extensive safety measures and health monitoring to prevent the development of acute or chronic beryllium disease, two pulmonary diseases created by an allergic reaction to beryllium in the lungs. Extensive health monitoring, engineering controls, and environment monitoring had to be set up with the University of Wisconsin department of Environment, Health and Safety. The hydrogen fluoride required for purification was also an extreme health hazard requiring thoughtful planning and execution. These dangers have made research a slow and tedious process. Simple processes, such as chemical handling and clean-up, can take large amounts of ingenuity and time. Other work has complemented the experimental research at Wisconsin to advance high temperature reactor goals. Modeling work has been performed in house to re

  13. Archaeometric analysis of Roman bronze coins from the Magna Mater temple using solid-state voltammetry and electrochemical impedance spectroscopy.

    Science.gov (United States)

    Di Turo, Francesca; Montoya, Noemí; Piquero-Cilla, Joan; De Vito, Caterina; Coletti, Fulvio; Favero, Gabriele; Doménech-Carbó, Antonio

    2017-02-22

    Voltammetry of microparticles (VMP) and electrochemical impedance spectroscopy (EIS) techniques, complemented by SEM-EDX and Raman spectroscopy, were applied to a set of 15 Roman bronze coins and one Tessera from the temple of Magna Mater (Rome, Italy). The archaeological site, dated back between the second half and the end of the 4th century A.D., presented a complicated stratigraphic context. Characteristic voltammetric patterns for cuprite and tenorite for sub-microsamples of the corrosion layers of the coins deposited onto graphite electrodes in contact with 0.10 M HClO4 aqueous solution yielded a grouping of the coins into three main groups. This grouping was confirmed and refined using EIS experiments of the coins immersed in air-saturated mineral water using the reduction of dissolved oxygen as a redox probe. The electrochemical grouping of coins corroborated the complex stratigraphy of the archaeological site and, above all, the reuse of the coins during the later periods due to the economic issues related to the fall of the Roman Empire.

  14. Uncover the mantle: rediscovering Gregório Lopes palette and technique with a study on the painting "Mater Misericordiae"

    Science.gov (United States)

    Antunes, Vanessa; Candeias, António; Oliveira, Maria J.; Carvalho, Maria L.; Dias, Cristina Barrocas; Manhita, Ana; Francisco, Maria J.; Costa, Sónia; Lauw, Alexandra; Manso, Marta

    2016-11-01

    Gregório Lopes (c. 1490-1550) was one of the most prominent painters of the renaissance and Mannerism in Portugal. The painting "Mater Misericordiae" made for the Sesimbra Holy House of Mercy, circa 1535-1538, is one of the most significant works of the artist, and his only painting on this theme, being also one of the most significant Portuguese paintings of sixteenth century. The recent restoration provided the possibility to study materially the painting for the first time, with a multianalytical methodology incorporating portable energy-dispersive X-ray fluorescence spectroscopy, scanning electron microscopy-energy-dispersive spectroscopy, micro-X-ray diffraction, micro-Raman spectroscopy and high-performance liquid chromatography coupled to diode array and mass spectrometry detectors. The analytical study was complemented by infrared reflectography, allowing the study of the underdrawing technique and also by dendrochronology to confirm the date of the wooden panels (1535-1538). The results of this study were compared with previous ones on the painter's workshop, and significant differences and similitudes were found in the materials and techniques used.

  15. Influencia del estilo directivo en la comunicación interna de las organizaciones. Una aplicación a las agencias de publicidad

    Directory of Open Access Journals (Sweden)

    Ángela Preciado-Hoyos

    2014-01-01

    Full Text Available Este artículo parte del presupuesto de que la manera como se dirige una organización entraña una forma específica de comunicar, por lo que al identificar el tipo de dirección que se despliega pueden preverse los com - portamientos de comunicación de un directivo. Para ello se formula un mo - delo de relaciones entre estilo directivo y comunicación interna. A partir de un análisis teórico se identifican cinco estilos prototípicos: laissez-faire , orientado a la tarea, orientado a las relaciones, liderazgo y liderazgo caris - mático, y se definen los modos de comunicación propios de cada uno de ellos. En la segunda parte del artículo, el modelo se contrasta en una mues - tra de agencias de publicidad españolas.

  16. Las competencias en la educación superior: tecnologías de gobierno para la gestión de la capacidad de agencia

    Directory of Open Access Journals (Sweden)

    Olga Cecilia Díaz Flórez

    2014-02-01

    Full Text Available El artículo sitúa las competencias como tecnología propia de un gobierno social gestado desde el neoliberalismo, cuyas prácticas de regulación son fortalecidas tanto con las políticas de los organismos internacionales como desde las políticas oficiales del país, destacando cómo en unos y otros se impulsan unas formas de gobierno flexible, pragmático, que responde adaptativamente a los cambios y que, sin embargo, favorecen prácticas que abren espacios a las fisuras, las contraconductas, los antagonismos: de un lado, con la promoción de la capacidad de agencia, y, de otro, con los escenarios que generan apertura, a través del impulso a la modulación y la automodulación.

  17. Interactive Virtual Reactor and Control Room for Education and Training at Universities and Nuclear Power Plants

    Energy Technology Data Exchange (ETDEWEB)

    Satoh, Yoshinori; Li, Ye; Zhu, Xuefeng; Rizwan, Uddin [University of Illinois, Urbana (United States)

    2014-08-15

    Efficient and effective education and training of nuclear engineering students and nuclear workers are critical for the safe operation and maintenance of nuclear power plants. With an eye toward this need, we have focused on the development of 3D models of virtual labs for education, training as well as to conduct virtual experiments. These virtual labs, that are expected to supplement currently available resources, and have the potential to reduce the cost of education and training, are most easily developed on game-engine platforms. We report some recent extensions to the virtual model of the University of Illinois TRIGA reactor.

  18. Supporting the President's Arms Control and Nonproliferation Agenda: Transparency and Verification for Nuclear Arms Reductions

    Energy Technology Data Exchange (ETDEWEB)

    Doyle, James E [Los Alamos National Laboratory; Meek, Elizabeth [Los Alamos National Laboratory

    2009-01-01

    The President's arms control and nonproliferation agenda is still evolving and the details of initiatives supporting it remain undefined. This means that DOE, NNSA, NA-20, NA-24 and the national laboratories can help define the agenda, and the policies and the initiatives to support it. This will require effective internal and interagency coordination. The arms control and nonproliferation agenda is broad and includes the path-breaking goal of creating conditions for the elimination of nuclear weapons. Responsibility for various elements of the agenda will be widely scattered across the interagency. Therefore an interagency mapping exercise should be performed to identify the key points of engagement within NNSA and other agencies for creating effective policy coordination mechanisms. These can include informal networks, working groups, coordinating committees, interagency task forces, etc. It will be important for NA-20 and NA-24 to get a seat at the table and a functional role in many of these coordinating bodies. The arms control and nonproliferation agenda comprises both mature and developing policy initiatives. The more mature elements such as CTBT ratification and a follow-on strategic nuclear arms treaty with Russia have defined milestones. However, recent press reports indicate that even the START follow-on strategic arms pact that is planned to be complete by the end of 2009 may take significantly longer and be more expansive in scope. The Russians called for proposals to count non-deployed as well as deployed warheads. Other elements of the agenda such as FMCT, future bilateral nuclear arms reductions following a START follow-on treaty, nuclear posture changes, preparations for an international nuclear security summit, strengthened international safeguards and multilateral verification are in much earlier stages of development. For this reason any survey of arms control capabilities within the USG should be structured to address potential needs

  19. O Brasil, a AIEA e o Regime de Não Proliferação Nuclear (1957-2014: entre a cooperação e a desconfiança.

    Directory of Open Access Journals (Sweden)

    Edson José Perosa

    2014-10-01

    Full Text Available A AIEA foi criada em 1957 após a proposta ‘‘átomos para paz’’ do presidente estadunidense Eisenhower, apresentada na ONU em 1953. A Agência deveria promover o uso pacífico da energia nuclear e coibir seu uso militar. O Tratado de Não Proliferação Nuclear (TNP, por sua vez, foi aprovado em 1968 e entrou em vigor em 1970. Os países que aderissem a esse tratado se comprometiam em não desenvolver armas nucleares e, por sua vez, os que já dispunham desses armamentos se comprometiam em reduzir seus arsenais. Esses são dois dos principais instrumentos do regime de não proliferação nuclear. O Brasil adotou uma postura crítica em relação ao TNP, criticando-o como sendo discriminatório. Com relação à AIEA, o governo brasileiro manteve contatos com a Agência e firmou tratados com ela – como o tratado tripartite Brasil-RFA-AIEA e o tratado quadripartite Brasil-Argentina-AIEA-ABACC.  Diferentemente de outros atores do regime de não proliferação, o Brasil pareceu mais disposto a aceitar a tutela da AIEA, ainda que não aderisse integralmente às salvaguardas da Agência. Ademais, a Agência – por meio dos tratados assinados com ela – pode ter sido um meio para o Brasil tentar legitimar seu programa nuclear como pacífico.

  20. Prioridades de intervención para la fase aguda de las emergencias complejas formuladas por nueve agencias de ayuda humanitaria

    Directory of Open Access Journals (Sweden)

    Carmen Sofía Carrillo Jaimes

    2004-01-01

    Full Text Available Las Emergencias Complejas son un problema de Salud Pública internacional de frecuencia y magnitud crecientes que producen una importante mortalidad y morbilidad especialmente durante su fase aguda. El objetivo de este estudio es identificar y analizar las áreas prioritarias de intervención en la fase aguda de una emergencia compleja formuladas en los manuales operativos de las principales agencias de ayuda, así como el nivel de desarrollo y estructuración de las actividades propuestas en cada área de prioridad. Métodos: Como material de estudio se utilizaron los manuales de intervención elaborados por 9 de las principales agencias de ayuda. Se procedió a un análisis cuantitativo de las 16 prioridades de intervención planteadas así como del nivel de formulación de cada prioridad en base al desarrollo de 73 variables o aspectos de las propuestas formuladas en los manuales. Resultados: El manual de ACNUR recoge el 90% de las 73 variables de desarrollo de las prioridades y el de Oficina de Coordinación de Asuntos Humanitarios de Naciones Unidas el 35% de las 73 variables. ACNUR presenta el mejor desarrollo de las variables no sanitarias, seguido de MSF y USAID. Médicos sin fronteras muestra un grado de desarrollo de las variables sanitarias del 97,3% seguido de ACNUR (94,7%, USAID y UNICEF (92,1%. Conclusiones: Se ha encontrado que ACNUR tiene la propuesta más integral y Oficina de Coordinación de Asuntos Humanitarios de Naciones Unidas la más discreta. Existe una tendencia general a desarrollar y unificar los indicadores de salud, mientras que otros aspectos no se desarrollan.

  1. A study on associations of Korean sample group for colors applied to the nuclear power plant control room

    Energy Technology Data Exchange (ETDEWEB)

    Oh, In Seok; Lee, Jung Woon; Lee, Yong Hee; Lee, Hyun Chul [Korea Atomic Energy Research Institute, Taejeon (Korea); Lee, Dhong Ha [Suwon University, Whasung (Korea)

    2002-05-01

    Colors are widely used to warn risk levels and to attract attention of the public. Korea Standard Nuclear Reactor Control Room (KSNRCR) also uses several colors to differentiate warnings, priorities, status, borders, and messages based on the HF010 guideline. However the previous studies showed that the general public not engaged in a specific job domain had different associations of colors as regulated in the standards or the guidelines. It is also expected that the general public not engaged in nuclear power plant industry will have different color association system from the color coding system applied to the KSNRCR. So, this study was performed to show whether there is any difference between color association of a sample Korean group and the color meanings specified in the HF010 guideline. The general public not engaged in the nuclear power plant industry have no idea of the color usage in the nuclear control room. So we converted the specific color usage situation into similar but general situations. In questionnaire, we gave subjects the general situation where color coding is appled and alternative colors which were applied to the HF010 guidelines. And we asked the subjects to choose the colors proper to the situation and to rank the colors according to the degree of suitability. A hundred college students participated in the experiment. 10 refs., 7 tabs. (Author)

  2. Current perspectives on the role of TRAMP in nuclear RNA surveillance and quality control

    Directory of Open Access Journals (Sweden)

    Pan K

    2015-04-01

    Full Text Available Kewu Pan, Zhe Huang, Jimmy Tsz Hang Lee, Chi-Ming Wong State Key Laboratory of Pharmaceutical Biotechnology, Department of Medicine, Shenzhen Institute of Research and Innovation, the University of Hong Kong, Pokfulam, Hong Kong Abstract: The TRAMP complex assists the nuclear exosome to degrade a broad range of ribonucleic acid (RNA substrates by increasing both exoribonucleolytic activity and substrate specificity. However, how the interactions between the TRAMP subunits and the components of the nuclear exosome regulate their functions in RNA degradation and substrate specificity remain unclear. This review aims to provide a summary of the recent findings on the role of the TRAMP complex in nuclear RNA degradation. The new insights from recent structural biological studies are discussed. Keywords: TRAMP, nuclear exosome, NEXT, RNA surveillance

  3. Defense Nuclear Facilities Safety Board: Improvements Needed to Strengthen Internal Control and Promote Transparency

    Science.gov (United States)

    2015-01-01

    includes guidance. DNFSB refers to guidance as “work practices” and are not mandatory . Page 15 GAO-15-181 Nuclear Safety Board Technical...Federal Programs Congressional Relations Public Affairs Please Print on Recycled Paper.

  4. Impact of holmium fibre laser radiation (λ = 2.1 μm) on the spinal cord dura mater and adipose tissue

    Energy Technology Data Exchange (ETDEWEB)

    Filatova, S A; Kamynin, V A; Ryabova, A V; Loshchenov, V B; Tsvetkov, V B; Kurkov, A S [A M Prokhorov General Physics Institute, Russian Academy of Sciences, Moscow (Russian Federation); Zelenkov, P V [N. N. Burdenko Scientific Research Neurosurgery Institute, Moscow (Russian Federation); Zolotovskii, I O [Ulyanovsk State University, Ulyanovsk (Russian Federation)

    2015-08-31

    The impact of holmium fibre laser radiation on the samples of biologic tissues (dura mater of spinal cord and adipose tissue with interlayers of muscle) is studied. The experimental results are evaluated by the size of carbonisation and coagulation necrosis zones. The experiment shows that in the case of irradiation of the spinal cord dura mater samples the size of carbonisation and coagulation necrosis zones is insignificant. In the adipose tissue the carbonisation zone is also insignificant, but the region of cellular structure disturbance is large. In the muscle tissue the situation is opposite. The cw laser operation provides clinically acceptable degree of destruction in tissue samples with a minimal carbonisation zone. (laser applications in medicine)

  5. Nuclear track microfilters in controlled drug delivery against chronic skin disease

    Energy Technology Data Exchange (ETDEWEB)

    Gopalani, D. E-mail: deflab@sancharnet.in; Jodha, A.S.; Saravanan, S.; Kumar, S

    2003-06-01

    Nuclear track microfilters have been developed for transdermal therapeutic system. The transdermal therapeutic method reduces the toxicity of the drug as compared to other conventional methods. For this purpose a slow drug release system containing the nuclear track microfilter was developed. This device was applied to the patients suffering from psoriasis and cellulites diseases. The delivery of the drug to the patient was confirmed through high performance liquid chromatography. The preliminary results have shown that patients are responding to drugs with minimum toxicity.

  6. Qualitative Considerations of Nuclear Forces at Lower Numbers and Implications for Future Arms Control Negotiations

    Science.gov (United States)

    2012-07-01

    above the other two. The decision to select a heuristic of grouping characteristics rather than ranking characteristics one through eight reflected...Survivability Variety of Yield Options This three tier matrix provided a heuristic framework for assessing the relative importance of each of the eight...a nuclear strike mission. They lack a nuclear stand-off capability and can only employ gravity bombs. There is significant risk to aircrew within

  7. The Future Nuclear Arms Control Agenda and Its Potential Implications for the Air Force

    Science.gov (United States)

    2015-08-01

    process aims to build habits of cooperation between the militaries and officials of the United States and China. There has been progress in pursuit of...impacts on China’s nuclear posture. Other statements have stressed that China’s future nuclear modernization is linked to the U.S.-China offense-defense...unique backgrounds. Such an oral history could be done with a mix of workshops, one-on-one interviews, and responses to written questions. Once

  8. Nuclear Factor-kappaB controls the reaggregation of 3D neurosphere cultures in vitro

    Directory of Open Access Journals (Sweden)

    D Widera

    2006-05-01

    Full Text Available The approach of reaggregation involves the regeneration and self-renewal of histotypical 3D spheres from isolated tissue kept in suspension culture. Reaggregated spheres can be used as tumour, genetic, biohybrid and neurosphere models. In addition the functional superiority of 3D aggregates over conventional 2D cultures developed the use of neurospheres for brain engineering of CNS diseases. Thus 3D aggregate cultures created enormous interest in mechanisms that regulate the formation of multicellular aggregates in vitro. Here we analyzed mechanisms guiding the development of 3D neurosphere cultures. Adult neural stem cells can be cultured as self-adherent clusters, called neurospheres. Neurospheres are characterised as heterogeneous clusters containing unequal stem cell sub-types. Tumour necrosis factor-alpha (TNF- alpha is one of the crucial inflammatory cytokines with multiple actions on several cell types. TNF- alpha strongly activates the canonical Nuclear Factor Kappa-B (NF-kappaB pathway. In order to investigate further functions of TNF in neural stem cells (NSCs we tested the hypothesis that TNF is able to modulate the motility and/or migratory behaviour of SVZ derived adult neural stem cells. We observed a significantly faster sphere formation in TNF treated cultures than in untreated controls. The very fast aggregation of isolated NSCs (<2h is a commonly observed phenomenon, though the mechanisms of 3D neurosphere formation remain largely unclear. Here we demonstrate for the first time, increased aggregation and enhanced motility of isolated NSCs in response to the TNF-stimulus. Moreover, this phenomenon is largely dependent on activated transcription factor NF-kappaB. Both, the pharmacological blockade of NF-kappaB pathway by pyrrolidine dithiocarbamate (PDTC or Bay11-7082 and genetic blockade by expression of a transdominant-negative super-repressor IkappaB-AA1 led to decreased aggregation.

  9. Evaluation of electromagnetic interference environment of the instrumentation and control systems in nuclear power units

    Energy Technology Data Exchange (ETDEWEB)

    Min, Moon-Gi; Lee, Jae-Ki; Ji, Yeong-Haw; Jo, Sung-Han [Korea Hydro & Nuclear Power Co., Ltd., 1312-70 Yuesong-daero, Yuseong-Gu, Daejeon 305-343 (Korea, Republic of); Kim, Hee-Je, E-mail: heeje@pusan.ac.kr [Pusan National University, 2, Busandaehak-ro 63beon-gil, Geumjeong-gu, Busan 609-735 (Korea, Republic of)

    2015-04-15

    Highlights: • We surveyed the electromagnetic emissions at the location of I&C systems. • We assessed the electromagnetic levels on reactor types from thirteen nuclear plants. • We evaluated the margin between plant emission limits and the highest composite levels. • We presented the formula of radiated susceptibility test levels to non-safety-related I&C systems. - Abstract: The electromagnetic interference (EMI) generated from sources in power units can interfere with digital Instrument and Control (I&C) systems. When EMI is emitted with conducted and radiated noise, it interferes with the signals of the I&C systems. Since the digital I&C systems are efficient and competitively priced, the analogue I&C systems have been upgraded and replaced with digital I&C systems, but these systems have less EMI immunity. When safety-related I&C systems are installed in the units, the verification of equipment EMI should not be done in site-specific tests but in test facilities. There are needs to do the overall site-specific EMI assessment of I&C systems depending on the reactor types from thirteen operating units. This study evaluated the margin between plant emission limits and the highest composite plant emissions of the EMI. When the non-safety-related I&C equipment or systems are placed in the units, there are no individual test levels of the radiated electrical field. If need be, the level should comply with the test levels of the radiated electrical field on the safety-related I&C systems. This paper presents the test levels of radiated electrical fields to non-safety-related I&C equipment or systems.

  10. Role of nuclear grade graphite in controlling oxidation in modular HTGRs

    Energy Technology Data Exchange (ETDEWEB)

    Windes, Willaim [Idaho National Lab. (INL), Idaho Falls, ID (United States); Strydom, G. [Idaho National Lab. (INL), Idaho Falls, ID (United States); Kane, J. [Idaho National Lab. (INL), Idaho Falls, ID (United States); Smith, R. [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2014-11-01

    The passively safe High Temperature Gas-cooled Reactor (HTGR) design is one of the primary concepts considered for Generation IV and Small Modular Reactor (SMR) programs. The helium cooled, nuclear grade graphite moderated core achieves extremely high operating temperatures allowing either industrial process heat or electricity generation at high efficiencies. In addition to their neutron moderating properties, nuclear grade graphite core components provide excellent high temperature stability, thermal conductivity, and chemical compatibility with the high temperature nuclear fuel form. Graphite has been continuously used in nuclear reactors since the 1940’s and has performed remarkably well over a wide range of core environments and operating conditions. Graphite moderated, gas-cooled reactor designs have been safely used for research and power production purposes in multiple countries since the inception of nuclear energy development. However, graphite is a carbonaceous material, and this has generated a persistent concern that the graphite components could actually burn during either normal or accident conditions [ , ]. The common assumption is that graphite, since it is ostensibly similar to charcoal and coal, will burn in a similar manner. While charcoal and coal may have the appearance of graphite, the internal microstructure and impurities within these carbonaceous materials are very different. Volatile species and trapped moisture provide a source of oxygen within coal and charcoal allowing them to burn. The fabrication process used to produce nuclear grade graphite eliminates these oxidation enhancing impurities, creating a dense, highly ordered form of carbon possessing high thermal diffusivity and strongly (covalently) bonded atoms.

  11. Stimulation of rat cranial dura mater with potassium chloride causes CGRP release into the cerebrospinal fluid and increases medullary blood flow.

    Science.gov (United States)

    Dux, Mária; Will, Christine; Eberhardt, Mirjam; Fischer, Michael J M; Messlinger, Karl

    2017-02-10

    Primary headaches may be accompanied by increased intracranial blood flow induced by the release of the potent vasodilator calcitonin gene-related peptide (CGRP) from activated meningeal afferents. We aimed to record meningeal and medullary blood flow simultaneously and to localize the sites of CGRP release in rodent preparations in vivo and ex vivo. Blood flow in the exposed rat parietal dura mater and the medulla oblongata was recorded by laser Doppler flowmetry, while the dura was stimulated by topical application of 60mM potassium chloride (KCl). Samples of jugular venous plasma and cerebrospinal fluid (CSF) collected from the cisterna magna were analysed for CGRP concentrations using an enzyme immunoassay. In a hemisected rat skull preparation lined with dura mater the CGRP releasing effect of KCl superfusion was examined. Superfusion of the dura mater with KCl decreased meningeal blood flow unless alpha-adrenoceptors were blocked by phentolamine, whereas the medullary blood flow was increased. The same treatment caused increased CGRP concentrations in jugular plasma and CSF and induced significant CGRP release in the hemisected rat skull preparation. Anaesthesia of the trigeminal ganglion by injection of lidocaine reduced increases in medullary blood flow and CGRP concentration in the CSF upon meningeal KCl application. CGRP release evoked by depolarisation of meningeal afferents is accompanied by increased blood flow in the medulla oblongata but not the dura mater. This discrepancy can be explained by the smooth muscle depolarising effect of KCl and the activation of sympathetic vasoconstrictor mechanisms. The medullary blood flow response is most likely mediated by CGRP released from activated central terminals of trigeminal afferents. Increased blood supply of the medulla oblongata and CGRP release into the CSF may also occur in headaches accompanying vigorous activation of meningeal afferents.

  12. The Effects of 910-MHz Electromagnetic Field on Rat Cranial Arachnoid and Dura Mater Collagen. The Axial Periodicity of Collagen Fibrils

    Directory of Open Access Journals (Sweden)

    Margaret Tzaphlidou

    2004-01-01

    Full Text Available The axial periodicity of rat arachnoid and dura mater collagen fibrils exposed to 910 MHz for 2 h/day for 30 consecutive days was measured by means of image analysis of electron-optical data. Such measurements were compared with those from sham-exposed animals. These measurements reveal that on exposure, the intermolecular interactions during collagen fibril assembly are affected.

  13. Virtual control desk for operators training: a case study for a nuclear power plant simulator; Mesa de controle virtual para treinamento de operadores: um estudo de caso para um simulador de usina nuclear

    Energy Technology Data Exchange (ETDEWEB)

    Aghina, Mauricio Alves da Cunha e

    2009-03-15

    Nuclear Power Plant (NPP) is a facility for electrical energy generation. Because of its high degree of complexity and very rigid norms of security it is extremely necessary that operators are very well trained for the NPP operation. A mistaken operation by a human operator may cause a shutdown of the NPP, incurring in a huge economical damage for the owner and for the population in the case of a electric net black out. To reduce the possibility of a mistaken operation, the NPP usually have a full scope simulator of the plant's control room, which is the physical copy of the original control room. The control of this simulator is a computer program that can generate the equal functioning of the normal one or some scenarios of accidents to train the operators in many abnormal conditions of the plant. A physical copy of the control room has a high cost for its construction, not only of its facilities but also for its physical components. The proposal of this work is to present a project of a virtual simulator with the modeling in 3D stereo of a control room of a given nuclear plant with the same operation functions of the original simulator. This virtual simulator will have a lower cost and serves for pretraining of operators with the intention of making them familiar to the original control room. (author)

  14. Evidence for novel age-dependent network structures as a putative primo vascular network in the dura mater of the rat brain

    Institute of Scientific and Technical Information of China (English)

    Ho-Sung Lee; Dai-In Kang; Seung Zhoo Yoon; Yeon Hee Ryu; Inhyung Lee; Hoon-Gi Kim; Byung-Cheon Lee; Ki Bog Lee

    2015-01-01

    With chromium-hematoxylin staining, we found evidence for the existence of novel age-depen-dent network structures in the dura mater of rat brains. Under stereomicroscopy, we noticed that chromium-hematoxylin-stained threadlike structures, which were barely observable in 1-week-old rats, were networked in specific areas of the brain, for example, the lateral lobes and the cerebella, in 4-week-old rats. In 7-week-old rats, those structures were found to have become larger and better networked. With phase contrast microscopy, we found that in 1-week-old rats, chromium-hematoxylin-stained granules were scattered in the same areas of the brain in which the network structures would later be observed in the 4- and 7-week-old rats. Such age-depen-dent network structures were examined by using optical and transmission electron microscopy, and the following results were obtained. The scattered granules fused into networks with increas-ing age. Cross-sections of the age-dependent network structures demonstrated heavily-stained basophilic substructures. Transmission electron microscopy revealed the basophilic substructures to be clusters with high electron densities consisting of nanosized particles. We report these data as evidence for the existence of age-dependent network structures in the dura mater, we discuss their putative functions of age-dependent network structures beyond the general concept of the dura mater as a supporting matrix.

  15. Robust control of entanglement in a Nitrogen-vacancy centre coupled to a Carbon-13 nuclear spin in diamond

    OpenAIRE

    Said, R S; Twamley, J.

    2009-01-01

    We address a problem of generating a robust entangling gate between electronic and nuclear spins in the system of a single nitrogen-vacany centre coupled to a nearest Carbon-13 atom in diamond against certain types of systematic errors such as pulse-length and off-resonance errors. We analyse the robustness of various control schemes: sequential pulses, composite pulses and numerically-optimised pulses. We find that numerically-optimised pulses, produced by the gradient ascent pulse engineeri...

  16. Applications of nuclear physics

    Science.gov (United States)

    Hayes, A. C.

    2017-02-01

    Today the applications of nuclear physics span a very broad range of topics and fields. This review discusses a number of aspects of these applications, including selected topics and concepts in nuclear reactor physics, nuclear fusion, nuclear non-proliferation, nuclear-geophysics, and nuclear medicine. The review begins with a historic summary of the early years in applied nuclear physics, with an emphasis on the huge developments that took place around the time of World War II, and that underlie the physics involved in designs of nuclear explosions, controlled nuclear energy, and nuclear fusion. The review then moves to focus on modern applications of these concepts, including the basic concepts and diagnostics developed for the forensics of nuclear explosions, the nuclear diagnostics at the National Ignition Facility, nuclear reactor safeguards, and the detection of nuclear material production and trafficking. The review also summarizes recent developments in nuclear geophysics and nuclear medicine. The nuclear geophysics areas discussed include geo-chronology, nuclear logging for industry, the Oklo reactor, and geo-neutrinos. The section on nuclear medicine summarizes the critical advances in nuclear imaging, including PET and SPECT imaging, targeted radionuclide therapy, and the nuclear physics of medical isotope production. Each subfield discussed requires a review article unto itself, which is not the intention of the current review; rather, the current review is intended for readers who wish to get a broad understanding of applied nuclear physics.

  17. Automated system of control of radioactive liquid effluents of patients submitted to therapy in hospitals of nuclear medicine (SACEL); Sistema automatizado de control de efluentes liquidos radiactivos de pacientes sometidos a terapia en hospitales de medicina nuclear (SACEL)

    Energy Technology Data Exchange (ETDEWEB)

    Ruiz C, M.A.; Rivero G, T.; Celis del Angel, L.; Sainz M, E.; Molina, G. [ININ, 52045 Ocoyoacac, Estado de Mexico (Mexico)]. e-mail: marc@nuclear.inin.mx

    2006-07-01

    Different hospitals of nuclear medicine require of the technical attendance for the design, construction and instrumentation of an effluents retention system coming from the room dedicated to the medical application of iodine 131, with the one object of giving execution to the normative requirements of radiological protection, settled down in the General Regulation of Radiological Safety (RGSR) emitted by the CNSNS in November, 1988 and in the corresponding official standards. An automatic system of flow measurement, the activity concentration of the effluents to the drainage, the discharges control and the automated report it will allow the execution of the national regulations, also the elimination of unhealthy activities as the taking of samples, analysis of those same and the corresponding paperwork, its will allow that the SACEL is capable of to carry out registrations that are to consult in an automated way. The changes in the demands of the National Commission of Nuclear Safety and Safeguards in relation to the liberation of radioactive material in hospitals by medical treatments, it has created the necessity to develop a system that quantifies and dose the liquid effluents of people under thyroid treatment with iodine-131 to the drainage. The Automated System of Control of radioactive liquids effluents generated in Hospitals of Nuclear Medicine (SACEL) developed in the National Institute of Nuclear Research, it fulfills this regulation, besides improving the work conditions for the medical and technical personnel of the hospital in that are installed, since this system has the advantage of to be totally automated and to require of a minimum of attendance. The SACEL is an electro-hydraulic system of effluents control, based in the alternate operation of two decay deposits of the activity of the material contaminated with iodine-131. The system allows to take a registration of those volumes and liberated dose, besides being able to be monitoring in remote

  18. Implementation of Unclassified Controlled Nuclear Information guidelines for fixed-site safeguards and security (FSSS) at Los Alamos National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Rood, P.L.

    1995-02-01

    Unclassified Controlled Nuclear Information (UCNI) is one type of sensitive information that DOE employees, including computer users, must now identify and protect. Guidelines to identify information as UCNI are gradually being put in place. The publication of Unclassified Controlled Nuclear Information Topical Guideline for Fixed-Site Safeguards and Security, TG-FSSS-1, is a major step in the development of UCNI guidelines. This DOE published guide cuts across and addresses many different programmatic areas including automated data processing. Our local guideline, Los Alamos National Laboratory Unclassified Controlled Nuclear Information Guideline for Fixed-Site Safeguards and Security, IG-LAFSSS-1, is based on TG-FSSS-1. In this paper, I plan to discuss the background of UCNI, the definition of UCNI, information that qualifies as UCNI, the consequences of information being UCNI, the development of UCNI guidelines, TG-FSSS-1 and IG-LAFSSS-1, the relationship of UCNI to classification, and the implementation of the IG-LAFSSS-1 at Los Alamos.

  19. AKT3 controls mitochondrial biogenesis and autophagy via regulation of the major nuclear export protein CRM-1.

    Science.gov (United States)

    Corum, Daniel G; Tsichlis, Philip N; Muise-Helmericks, Robin C

    2014-01-01

    Our previous work has shown that Akt3 is required for mitochondrial biogenesis in primary human endothelial cells (ECs) and in Akt3-null mice; Akt3 affects subcellular localization of peroxisome proliferator-activated receptor γ coactivator-1 (PGC-1α), the master regulator of mitochondrial biogenesis. The purpose of this study is to determine the mechanism by which Akt3 controls the subcellular distribution of PGC-1α and to explore the effect on mitochondrial biogenesis and turnover during angiogenesis. Here we use standard biochemical analyses and Akt3-knockdown strategies to show that Akt3 controls the stabilization of chromosome maintenance region-1 (CRM-1), the major nuclear export receptor. Site-directed mutagenesis and association analyses show that PGC-1α nuclear export is CRM-1 dependent. Akt3 knockdown and CRM-1 overexpression cause 3-fold reductions in PGC-1α target gene expression, compared to control levels. Akt3 inhibition causes autophagy, as measured by autophagosome formation, in a CRM-1-dependent, Akt1/mTOR-independent pathway. In vivo, Akt3-null and heterozygous mice show dose-dependent decreases in angiogenesis compared to wild-type littermates (~5- and 2.5-fold decreases, respectively), as assessed by Matrigel plug assays. This correlates with an ~1.5-fold decrease in mitochondrial Cox IV expression. Our studies suggest that Akt3 is a regulator of mitochondrial dynamics in the vasculature via regulation of CRM-1-dependent nuclear export.

  20. Controlling the atom. The beginnings of nuclear regulation 1946--1962

    Energy Technology Data Exchange (ETDEWEB)

    Mazuzan, G.T.; Walker, J.S.

    1997-08-01

    This book traces the early history of nuclear power regulation in the US. It focuses on the Atomic Energy Commission (AEC), the federal agency that until 1975 was primarily responsible for planning and carrying out programs to protect public health and safety from the hazards of the civilian use of nuclear energy. It also describes the role of other groups that figured significantly in the development of regulatory policies, including the congressional Joint Committee on Atomic Energy, federal agencies other than the AEC, state governments, the nuclear industry, and scientific organizations. And it considers changes in public perceptions of and attitudes toward atomic energy and the dangers of radiation exposure. The context in which regulatory programs evolved is a rich and complex mixture of political, legislative, legal, technological, scientific, and administrative history. The basic purpose of this book is to provide the Nuclear Regulatory Commission (NRC), which inherited responsibility for nuclear safety after Congress disbanded the AEC, and the general public with information on the historical antecedents and background of regulatory issues.

  1. National phantoms bank for the service of nuclear medicine in Cuba. Utility for the quality control of the instrumentation; Banco de fantomas nacional para los servicios de medicina nuclear en Cuba. Utilidad para el control de calidad de la instrumentacion

    Energy Technology Data Exchange (ETDEWEB)

    Varela C, C.; Diaz B, M. [CCEEM, Calle 4 No. 455 (altos) e/19 y 21, Vedado, Ciudad Habana (Cuba); Lopez B, G.M. [CPHR, Calle 20 No. 4113 e/41 y 47, Playa Ciudad Habana (Cuba)]. e-mail: consuelo.varela@infomed.sld.cu

    2006-07-01

    Although, most of the applications in Nuclear Medicine have diagnostic ends, its going enlarging considerably the therapeutic applications. So that the diagnostic accuracy or the therapy effectiveness have not been affected, it becomes indispensable the quality control of the instrumentation, independently of its technological complexity and/or its exploitation period. Before the real lack of phantoms in the institutions, it was created a bank that puts to disposition of all the institutions, the existent phantoms in the country, and those that are going acquired, centralized by the State Control of Medical Equipment Center (CCEEM) and with Web access in its place www.eqmed.sld.cu. Having like base the elaboration of the National Protocol for the Quality Control of the Instrumentation in Nuclear Medicine that keeps in mind the international normative and the own existent conditions, were dictated and established two national regulations and its are being carried out the first audits to the instrumentation quality. These have evidenced the partial realization of the established quality controls in the services, the necessity to make aware as for the fulfillment of the criteria and quality concepts for the instrumentation, as well as the necessity to increase the phantoms number to the bank to guarantee the fulfillment of the Quality Control Programs. (Author)

  2. Radiological protection and routinary controls of an activimeter with a cesium and barium sources in an nuclear medicine center; Proteccion radiologica y controles rutinarios de un activimetro con fuentes de cesio y bario en un centro de medicina nuclear

    Energy Technology Data Exchange (ETDEWEB)

    Morales L, M.E. [IPEN INEN, Centro de Medicina Nuclear, Av. Aviacion 3799, Lima 34 (Peru)]. e-mail: toyoco3000@hotmail.com

    2006-07-01

    In the present work the results when carrying out the routine controls in a Deluxe Isotope (Calibrator II) equipment, with some sources of Cesium 137 and Barium 133, in a Nuclear Medicine Center that operates from the year 1983 in a modern one construction inside the Institute of Neoplastic Illnesses (INEN) are shown. Taking in account the Radiological Protection measures to verify if the equipment responds to the personnel's demands in the measurements of activities of the diverse radionuclides that are used in different types of exams that are carried out in this Nuclear Medicine Center are the objectives of this work. This Center was equipped initially with donated equipment by the International Atomic Energy Agency (IAEA) with those that it develops assistance, educational works and of research, giving services to patients of the INEN and other public and private medical centers. (Author)

  3. Nuclear factor I-C reciprocally regulates adipocyte and osteoblast differentiation via control of canonical Wnt signaling.

    Science.gov (United States)

    Zhou, Jie; Wang, Shan; Qi, Qi; Yang, Xiaoyue; Zhu, Endong; Yuan, Hairui; Li, Xuemei; Liu, Ying; Li, Xiaoxia; Wang, Baoli

    2017-01-25

    Nuclear factor I-C (NFIC) has recently been identified as an important player in osteogenesis and bone homeostasis in vivo However, the molecular mechanisms involved have yet to be defined. In the current study, Nfic expression was altered in primary marrow stromal cells and established progenitor lines after adipogenic and osteogenic treatment. Overexpression of Nfic in stromal cells ST2, mesenchymal cells C3H10T1/2, and primary marrow stromal cells inhibited adipogenic differentiation, whereas it promoted osteogenic differentiation. Conversely, silencing of endogenous Nfic in the cell lines enhanced adipogenic differentiation, whereas it blocked osteogenic differentiation. Mechanism investigations revealed that Nfic overexpression promoted nuclear translocation of β-catenin and increased nuclear protein levels of β-catenin and transcription factor 7-like 2 (TCF7L2). Promoter studies and the chromatin immunoprecipitation (ChIP) assay revealed that NFIC directly binds to the promoter of low-density lipoprotein receptor-related protein 5 (Lrp5) and thereafter transactivates the promoter. Finally, inactivation of canonical Wnt signaling in ST2 attenuated the inhibition of adipogenic differentiation and stimulation of osteogenic differentiation by NFIC. Our study suggests that NFIC balances adipogenic and osteogenic differentiation from progenitor cells through controlling canonical Wnt signaling and highlights the potential of NFIC as a target for new therapies to control metabolic disorders like osteoporosis and obesity.-Zhou, J., Wang, S., Qi, Q., Yang, X., Zhu, E., Yuan, H., Li, X., Liu, Y., Li, X., Wang, B. Nuclear factor I-C reciprocally regulates adipocyte and osteoblast differentiation via control of canonical Wnt signaling.

  4. Assessing controls on perched saturated zones beneath the Idaho Nuclear Technology and Engineering Center, Idaho

    Science.gov (United States)

    Mirus, Benjamin B.; Perkins, Kim S.; Nimmo, John R.

    2011-01-01

    Waste byproducts associated with operations at the Idaho Nuclear Technology and Engineering Center (INTEC) have the potential to contaminate the eastern Snake River Plain (ESRP) aquifer. Recharge to the ESRP aquifer is controlled largely by the alternating stratigraphy of fractured volcanic rocks and sedimentary interbeds within the overlying vadose zone and by the availability of water at the surface. Beneath the INTEC facilities, localized zones of saturation perched on the sedimentary interbeds are of particular concern because they may facilitate accelerated transport of contaminants. The sources and timing of natural and anthropogenic recharge to the perched zones are poorly understood. Simple approaches for quantitative characterization of this complex, variably saturated flow system are needed to assess potential scenarios for contaminant transport under alternative remediation strategies. During 2009-2011, the U.S. Geological Survey (USGS), in cooperation with the U.S. Department of Energy, employed data analysis and numerical simulations with a recently developed model of preferential flow to evaluate the sources and quantity of recharge to the perched zones. Piezometer, tensiometer, temperature, precipitation, and stream-discharge data were analyzed, with particular focus on the possibility of contributions to the perched zones from snowmelt and flow in the neighboring Big Lost River (BLR). Analysis of the timing and magnitude of subsurface dynamics indicate that streamflow provides local recharge to the shallow, intermediate, and deep perched saturated zones within 150 m of the BLR; at greater distances from the BLR the influence of streamflow on recharge is unclear. Perched water-level dynamics in most wells analyzed are consistent with findings from previous geochemical analyses, which suggest that a combination of annual snowmelt and anthropogenic sources (for example, leaky pipes and drainage ditches) contribute to recharge of shallow and

  5. Core Power Control of the fast nuclear reactors with estimation of the delayed neutron precursor density using Sliding Mode method

    Energy Technology Data Exchange (ETDEWEB)

    Ansarifar, G.R., E-mail: ghr.ansarifar@ast.ui.ac.ir; Nasrabadi, M.N.; Hassanvand, R.

    2016-01-15

    Highlights: • We present a S.M.C. system based on the S.M.O for control of a fast reactor power. • A S.M.O has been developed to estimate the density of delayed neutron precursor. • The stability analysis has been given by means Lyapunov approach. • The control system is guaranteed to be stable within a large range. • The comparison between S.M.C. and the conventional PID controller has been done. - Abstract: In this paper, a nonlinear controller using sliding mode method which is a robust nonlinear controller is designed to control a fast nuclear reactor. The reactor core is simulated based on the point kinetics equations and one delayed neutron group. Considering the limitations of the delayed neutron precursor density measurement, a sliding mode observer is designed to estimate it and finally a sliding mode control based on the sliding mode observer is presented. The stability analysis is given by means Lyapunov approach, thus the control system is guaranteed to be stable within a large range. Sliding Mode Control (SMC) is one of the robust and nonlinear methods which have several advantages such as robustness against matched external disturbances and parameter uncertainties. The employed method is easy to implement in practical applications and moreover, the sliding mode control exhibits the desired dynamic properties during the entire output-tracking process independent of perturbations. Simulation results are presented to demonstrate the effectiveness of the proposed controller in terms of performance, robustness and stability.

  6. Sipping machine control system new design to perform integrity of nuclear fuel test in Cofrentes power plant

    Energy Technology Data Exchange (ETDEWEB)

    Palomo, M., E-mail: mpalomo@iqn.upv.es [Departamento de Ingenieria Quimica y Nuclear. Universidad Politecnica de Valencia (Spain); Urrea, M., E-mail: Matias.urrea@iberdrola.es [C.N.Cofrentes - Iberdrola Generacion S.A., Cofrentes, Valencia (Spain); Curiel, M., E-mail: m.curiel@lainsa.com [LAINSA Grupo Dominguis, Valencia (Spain); Arnaldos, A., E-mail: a.arnaldos@titaniast.com [TITANIA Servicios Tecnologicos SL, Grupo Dominguis, Valencia (Spain)

    2011-07-01

    This paper we present is related to SIPPING machine control system new design to perform integrity of nuclear fuel test. This test is a non destructive technique used for evaluating the radiated nuclear fuel coating structural integrity. It is based on the radioactive emission detection of fission elements in the reactor cooling system, using the fuel inspection equipment (SIPPING). SIPPING equipment consists of one simultaneous test bell-shaped vessel of eight fuel elements, and another one for individual element test, a control workstation and some accessories (cables, thermocouples, hoses). SIPPING inspection is carried out by means of fuel element vessel. Through air injection, water flows around the element and heat evacuation is reduced, so fuel elements temperature increases. Those elements with faults shall expelled fission components dissolved in water and/or as a gas component. The project aim is the SIPPING system control design and software based on LabVIEW, for control, monitoring and documentation of the SIPPING Test. This project shall give a major functionality to the system and, at the same time, shall facilitate the user a friendlier and interactive environment allowing: to substitute the present work platform with a real-time electronic system based on cRIO and a control software ad-hoc designed for SIPPING system; to equip new system of a major redundancy for data storage, minimising loss probability of the same. (author)

  7. Sipping machine control system new design to perform integrity of nuclear fuel test in Cofrentes power plant

    Energy Technology Data Exchange (ETDEWEB)

    Curiel, M. [Logistica y Acondicionamientos Industriales SAU, Sorolla Center, local 10, Av. de las Cortes Valencianas No. 58, 46015 Valencia (Spain); Palomo, M. J. [ISIRYM, Universidad Politecnica de Valencia, Camino de Vera s/n, Valencia (Spain); Urrea, M. [Iberdrola Generacion S. A., Central Nuclear Cofrentes, Carretera Almansa Requena s/n, 04662 Cofrentes, Valencia (Spain); Vaquer, J., E-mail: m.curiel@lainsa.co [TITANIA Servicios Tecnologicos SL, Sorolla Center, local 10, Av. de las Cortes Valencianas No. 58, 46015 Valencia (Spain)

    2010-10-15

    This paper related to Sipping machine control system new design to perform integrity of nuclear fuel test. This test is a non destructive technique used for evaluating the radiated nuclear fuel coating structural integrity. It is based on the radioactive emission detection of fission elements in the reactor cooling system, using the fuel inspection equipment Sipping. The equipment consists of one simultaneous test bell-shaped vessel of eight fuel elements, and another one for individual element test, a control workstation and some accessories (cables, thermocouples, hoses). Sipping inspection is carried out by means of fuel element vessel. Through air injection, water flows around the element and heat evacuation is reduced, so fuel elements temperature increases. Those elements with faults shall expelled fission components dissolved in water and/or as a gas component. The project aim is the Sipping system control design and software based on LabVIEWTM, for control, monitoring and documentation of the Sipping test. This project shall give a major functionality to the system and, at the same time, shall facilitate the user a friendlier and interactive environment allowing: 1) To substitute the present work platform with a real-time electronic system based on cRIO and a control software ad-hoc designed for Sipping system. 2) To equip new system of a major redundancy for data storage, minimising loss probability of the same. (Author)

  8. Review report: safety and reliability issues on digital instrumentation and control systems in nuclear power plants and United States Nuclear Regulatory Commission`s dispositions

    Energy Technology Data Exchange (ETDEWEB)

    Watanabe, Norio; Suzudo, Tomoaki [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    1998-09-01

    Recently, digital instrumentation and control (I and C) systems have been applied to nuclear power plants (NPPs) in various countries. Introduction of digital I and C systems, however, raises special issues on design, implementation, safety and licensing. Since FY 1997, the Japan Atomic Energy Research Institute (JAERI) has been carrying out a project, Study on Reliability of Digital I and C Systems, which includes extensive reviews of design approaches, technical standards, regulatory processes, especially, in the United States. This report summarizes the results from the study of National Research Council (NRC) and the U.S. Nuclear Regulatory Commission`s (USNRC`s) responses to the recommendations made by the NRC`s study. That study identified six technical key issues (system aspects of digital I and C technology, software quality assurance, common-mode software failure potential, safety and reliability assessment methods, human factors and man-machine interface, dedication of commercial off-the-shelf hardware and software) and two strategic key issues (case-by-case licensing process, adequacy of technical infrastructure) that arise from the introduction of digital I and C technology and then, made recommendations to the USNRC for coping with digital I and C applications. The USNRC responded to each recommendation and showed their own dispositions in which the USNRC agreed with most of the recommendations. In Japan, it is expected that introduction of digital I and C technology is inevitable in NPPs because the vendors are gradually discontinuing support and stocking of analog components. To cope with such situations, there is a need to develop and update the standards and guidelines applicable to digital I and C technology. The key issues and the USNRC`s dispositions provided in this report is believed to be useful for developing and updating them. (J.P.N.)

  9. Nuclear exports. Parliamentary control and confidentiality; Parlamentarische Kontrolle und Geheimhaltungsbeduerftigkeit bei Nuklearexporten. Zum Urteil des Bundesverfassungsgerichts vom 21. Oktober 2014

    Energy Technology Data Exchange (ETDEWEB)

    Feldmann, Ulrike

    2015-03-15

    With its decision taken on 21. October 2014 (Az.: 2 BvE 5/11) the Federal Constitutional Court (BVerfG) decided during court proceedings between administrative bodies on the scope and limits of the parliamentary right of information. Even though the proceeding did not deal with nuclear exports but arm exports, foreign trade law, however, does not only designate an export licence obligation for military weapons but also for so called dual-use goods meaning goods, which can be used both for friendly as well as for military purposes. The export of these goods requires according to the so-called Dual-Use Regulation (EG) 428/2009 a licence. Annex I category 0 of the regulation (EG) 428/2009 lists a variety of nuclear materials, plants and equipment items for which this licence applies. In the same manner as arm exports, also exports of nuclear dual-use goods are being discussed in a special cabinet committee, the Federal Security Council (BSR), which shall coordinate cross-departmentally the German security and defence policy under consideration of economic interests and which categorises its results, according to the rules of procedure, as confidential. Also legally not regulated but common ''preliminary enquiries'' at the responsible Federal Ministry or rather Federal Office of Economics and Export Control by companies which plan an export and want to affirm the general approval for their export business prior to conclusion of contract take not only place for arm exports but also for nuclear dual-use goods. The decision by the Federal Constitutional Court can be applied to consultations about the authorisation of nuclear dual-use goods.

  10. Comparison of the Standards applied to Instrumentation and Control Systems for Nuclear Power Stations in Korea and Russia

    Energy Technology Data Exchange (ETDEWEB)

    Park, Joo Hyun; Hwang, In Koo; Lee, Dong Young

    2005-04-15

    This report describes a comparison result of technical standards applied to instrumentation and control systems for nuclear power plants between in Korea and in Russia. Russia also has a state-run organization authorized to conduct approval, cancellation, and audit in use of nuclear facility or equipment. The Russian standards for nuclear instrumentation and control equipment are analogous with the Korean ones in the aspect of basic concepts and principles. However, there are some differences in document structure, design requirements, qualification test items, depth of contents between two standard systems. The biggest deviation exists in the standard documents for seismic qualification and electromagnetic interference qualification. Korean seismic qualification standard utilizing US approach, defines testing and qualification methods specifically and clearly. Russian standards however provide only conceptual definitions and requirements in the seismic related aspects. Therefore, it is conceived that any equipment or system qualified seismically in accordance with Korean standards should additionally provide technical evidence that it is satisfactory with Russian standards as well. In electromagnetic interference qualification, because Russian standard requires more testing items than the current Korean standard, the additional qualification tests are necessary to meet the Russian requirements. However, these additional test items are based on IEC(International Electrotechnical Commission), therefore it is not a problem to perform those tests in a Korean testing facility.

  11. 77 FR 43506 - DoD Unclassified Controlled Nuclear Information (UCNI)

    Science.gov (United States)

    2012-07-25

    ... abbreviated ``DOD UCNI'') at the bottom on: the outside of the front cover, if any; the outside of the back...(s) and associated electrical systems, barriers, and back-up power systems not observable from a... adversary to defeat a security measure, e.g., fire, safety, nuclear accident, radiological release, or...

  12. Nuclear Compartmentalization Contributes to Stage-Specific Gene Expression Control in Trypanosoma cruzi

    Science.gov (United States)

    Pastro, Lucía; Smircich, Pablo; Di Paolo, Andrés; Becco, Lorena; Duhagon, María A.; Sotelo-Silveira, José; Garat, Beatriz

    2017-01-01

    In the protozoan parasite Trypanosoma cruzi, as in other trypanosomatids, transcription of protein coding genes occurs in a constitutive fashion, producing large polycistronic transcription units. These units are composed of non-functionally related genes which are pervasively processed to yield each mRNA. Therefore, post-transcriptional processes are crucial to regulate gene expression. Considering that nuclear compartmentalization could contribute to gene expression regulation, we comparatively studied the nuclear, cytoplasmic and whole cell transcriptomes of the non-infective epimastigote stage of T. cruzi, using RNA-Seq. We found that the cytoplasmic transcriptome tightly correlates with the whole cell transcriptome and both equally correlate with the proteome. Nonetheless, 1,200 transcripts showed differential abundance between the nuclear and cytoplasmic fractions. For the genes with transcript content augmented in the nucleus, significant structural and compositional differences were found. The analysis of the reported epimastigote translatome and proteome, revealed scarce ribosome footprints and encoded proteins for them. Ontology analyses unveiled that many of these genes are distinctive of other parasite life-cycle stages. Finally, the relocalization of transcript abundance in the metacyclic trypomastigote infective stage was confirmed for specific genes. While gene expression is strongly dependent on transcript steady-state level, we here highlight the importance of the distribution of transcripts abundance between compartments in T. cruzi. Particularly, we show that nuclear compartmentation is playing an active role in the developmental stage determination preventing off-stage expression. PMID:28243589

  13. Permeability of dura mater

    DEFF Research Database (Denmark)

    Tfelt-Hansen, Peer Carsten

    2011-01-01

    In the wake of cortical spreading depression (CSD) it has been suggested that noxious substances diffuse through the dura with resulting firing of epidural nerves. In my view this is unlikely because there are good reasons to suggest that there must be a dura-brain barrier. Alternatively collater...

  14. Program for upgrading nuclear materials protection, control, and accounting at all facilities within the All-Russian Institute of Experimental Physics (VNIIEF)

    Energy Technology Data Exchange (ETDEWEB)

    Yuferev, V.; Zhikharev, S.; Yakimov, Y. [All-Russian Inst. of Experimental Physics, Moscow (Russian Federation)] [and others

    1998-12-31

    As part of the Department of Energy-Russian program for strengthening nuclear material protection, control, and accounting (MPC and A), plans have now been formulated to install an integrated MPC and A system at all facilities containing large quantities of weapons-usable nuclear material within the All-Russian Institute of Experimental Physics (VNIIEF, Arzamas-16) complex. In addition to storage facilities, the complex houses a number of critical facilities used to conduct nuclear physics research and facilities for developing procedures for disassembly of nuclear weapons.

  15. Active Interrogation using Photofission Technique for Nuclear Materials Control and Accountability

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Haori [Oregon State Univ., Corvallis, OR (United States)

    2016-03-31

    Innovative systems with increased sensitivity and resolution are in great demand to detect diversion and to prevent misuse in support of nuclear materials management for the U.S. fuel cycle. Nuclear fission is the most important multiplicative process involved in non-destructive active interrogation. This process produces the most easily recognizable signature for nuclear materials. In addition to thermal or high-energy neutrons, high-energy gamma rays can also excite a nucleus and cause fission through a process known as photofission. Electron linear accelerators (linacs) are widely used as the interrogating photon sources for inspection methods involving photofission technique. After photofission reactions, prompt signals are much stronger than the delayed signals, but it is difficult to quantify them in practical measurements. Delayed signals are easily distinguishable from the interrogating radiation. Linac-based, advanced inspection techniques utilizing the delayed signals after photofission have been extensively studied for homeland security applications. Previous research also showed that a unique delayed gamma ray energy spectrum exists for each fissionable isotope. In this work, high-energy delayed γ-rays were demonstrated to be signatures for detection, identification, and quantification of special nuclear materials. Such γ-rays were measured in between linac pulses using independent data acquisition systems. A list-mode system was developed to measure low-energy delayed γ-rays after irradiation. Photofission product yields of 238U and 239Pu were determined based on the measured delayed γ-ray spectra. The differential yields of delayed γ-rays were also proven to be able to discriminate nuclear from non-nuclear materials. The measurement outcomes were compared with Monte Carlo simulation results. It was demonstrated that the current available codes have capabilities and limitations in the simulation of photofission process. A two

  16. LA AGENCIA DE LA NIÑA Y EL NIÑO EN LA CONDICIÓN PRE-CIUDADANA AGENCY (CHILDHOOD IN THE PRE-CITIZEN CONDITION

    Directory of Open Access Journals (Sweden)

    González Coto, Marcela

    2012-05-01

    Full Text Available Resumen: El presente ensayo se deriva del trabajo que recientemente han desarrollado la Fundación PANIAMOR y la Dirección General del Programa CEN-CINAI del Ministerio de Salud, sobre la formación ciudadana de los niños y las niñas costarricenses en la primera infancia. Las acciones conjuntas se han enfocado en la capacidad de agencia de los niños y las niñas, entendida como la disposición para explorar, reflexionar, actuar y valorarse en sus entornos como sujetos políticos. Para este fin, en este ensayo se lleva a cabo un análisis crítico de los modelos ideológicos y culturales que, en la sociedad contemporánea, legitiman y fomentan la condición de “pre-ciudadanía” de la infancia, mermando su desempeño, presente y futuro, como ciudadanos plenos de la sociedad. El análisis se sustenta en materiales diversos, de distintos orígenes, todos relativos a las condiciones actuales de la infancia y las formas como se restringen estas capacidades de agencia. El ensayo también aborda las dificultades y obstáculos que enfrenta un replanteamiento de las relaciones entre adultos y niños. También se documentan los esfuerzos recientes, tanto locales como internacionales, para crear marcos alternativos desde los cuales replantear la relación institucional entre unos y otros. Como principal resultado del ensayo, se delinean un conjunto de directrices, con expresión curricular, que pueden sustentar el desarrollo de las capacidades de agencia infantil con una manifestación directa en la niñez ciudadana, la cual, se plantea, se articula en tres dimensiones o ejes de desarrollo (la responsabilidad, la autonomía y el pensamiento complejo.Abstract: This essay is derived from the works that have recently developed the PANIAMOR Foundation and the General Board of Directors of the CEN-CINAI Program of the National Ministry of Health, on the civic education of Costa Rican children in early childhood. Joint activities have focused on the

  17. Nuclear analytical chemistry

    Energy Technology Data Exchange (ETDEWEB)

    Brune, D.; Forkman, B.; Persson, B.

    1984-01-01

    This book covers the general theories and techniques of nuclear chemical analysis, directed at applications in analytical chemistry, nuclear medicine, radiophysics, agriculture, environmental sciences, geological exploration, industrial process control, etc. The main principles of nuclear physics and nuclear detection on which the analysis is based are briefly outlined. An attempt is made to emphasise the fundamentals of activation analysis, detection and activation methods, as well as their applications. The book provides guidance in analytical chemistry, agriculture, environmental and biomedical sciences, etc. The contents include: the nuclear periodic system; nuclear decay; nuclear reactions; nuclear radiation sources; interaction of radiation with matter; principles of radiation detectors; nuclear electronics; statistical methods and spectral analysis; methods of radiation detection; neutron activation analysis; charged particle activation analysis; photon activation analysis; sample preparation and chemical separation; nuclear chemical analysis in biological and medical research; the use of nuclear chemical analysis in the field of criminology; nuclear chemical analysis in environmental sciences, geology and mineral exploration; and radiation protection.

  18. Fault Diagnosis with Multi-State Alarms in a Nuclear Power Control Simulation

    Energy Technology Data Exchange (ETDEWEB)

    Stuart A. Ragsdale; Roger Lew; Ronald L. Boring

    2014-09-01

    This research addresses how alarm systems can increase operator performance within nuclear power plant operations. The experiment examined the effects of two types of alarm systems (two-state and three-state alarms) on alarm compliance and diagnosis for two types of faults differing in complexity. We hypothesized the use of three-state alarms would improve performance in alarm recognition and fault diagnoses over that of two-state alarms. Sensitivity and criterion based on the Signal Detection Theory were used to measure performance. We further hypothesized that operator trust would be highest when using three-state alarms. The findings from this research showed participants performed better and had more trust in three-state alarms compared to two-state alarms. Furthermore, these findings have significant theoretical implications and practical applications as they apply to improving the efficiency and effectiveness of nuclear power plant operations.

  19. FAULT DIAGNOSIS WITH MULTI-STATE ALARMS IN A NUCLEAR POWER CONTROL SIMULATOR

    Energy Technology Data Exchange (ETDEWEB)

    Austin Ragsdale; Roger Lew; Brian P. Dyre; Ronald L. Boring

    2012-10-01

    This research addresses how alarm systems can increase operator performance within nuclear power plant operations. The experiment examined the effect of two types of alarm systems (two-state and three-state alarms) on alarm compliance and diagnosis for two types of faults differing in complexity. We hypothesized three-state alarms would improve performance in alarm recognition and fault diagnoses over that of two-state alarms. We used sensitivity and criterion based on Signal Detection Theory to measure performance. We further hypothesized that operator trust would be highest when using three-state alarms. The findings from this research showed participants performed better and had more trust in three-state alarms compared to two-state alarms. Furthermore, these findings have significant theoretical implications and practical applications as they apply to improving the efficiency and effectiveness of nuclear power plant operations.

  20. Thermal control of high energy nuclear waste, space option. [mathematical models

    Science.gov (United States)

    Peoples, J. A.

    1979-01-01

    Problems related to the temperature and packaging of nuclear waste material for disposal in space are explored. An approach is suggested for solving both problems with emphasis on high energy density waste material. A passive cooling concept is presented which utilized conduction rods that penetrate the inner core. Data are presented to illustrate the effectiveness of the rods and the limit of their capability. A computerized thermal model is discussed and developed for the cooling concept.

  1. Active Interrogation using Photofission Technique for Nuclear Materials Control and Accountability

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Haori [Oregon State Univ., Corvallis, OR (United States)

    2016-03-31

    Innovative systems with increased sensitivity and resolution are in great demand to detect diversion and to prevent misuse in support of nuclear materials management for the U.S. fuel cycle. Nuclear fission is the most important multiplicative process involved in non-destructive active interrogation. This process produces the most easily recognizable signature for nuclear materials. In addition to thermal or high-energy neutrons, high-energy gamma rays can also excite a nucleus and cause fission through a process known as photofission. Electron linear accelerators (linacs) are widely used as the interrogating photon sources for inspection methods involving photofission technique. After photofission reactions, prompt signals are much stronger than the delayed signals, but it is difficult to quantify them in practical measurements. Delayed signals are easily distinguishable from the interrogating radiation. linac-based, advanced inspection techniques utilizing the delayed signals after photofission have been extensively studied for homeland security applications. Previous research also showed that a unique delayed gamma ray energy spectrum exists for each fissionable isotope.

  2. Efecto de un plan educativo en la capacidad de agencia de autocuidado del paciente con hipertensión arterial en una institución de segundo nivel

    Directory of Open Access Journals (Sweden)

    Diana Marcela Achury-Saldaña

    2013-01-01

    Full Text Available El propósito de este estudio fue determinar el efecto de un plan educativo en la capacidad de agencia de autocuidado del pa- ciente hipertenso en una institución de segundo nivel. Materiales y métodos: se realizó un estudio de intervención pre y postest, con la participación de 83 pacientes con diagnóstico de hipertensión arterial, a quienes se les aplicó el instrumento “ Evaluación de la capacidad de agencia de autocuidado en el paciente hipertenso ” al inicio del estudio y tres meses posteriores a la implementación del plan educativo. Resultados: el plan educativo mejoró tanto la capacidad de agencia de autocuidado global como sus rangos, encontrando significancia estadística con un valor de probabilidad menor de 0,002 y de 0,0001 respectivamente. Conclusiones: las intervenciones educativas estructuradas a partir de la identificación de las necesidades individuales de información, en conjunto con el empoderamiento del individuo y el seguimiento por parte del profesional de enfermería, permiten alcanzar conductas permanentes de autocuidado que facilitan el autoconocimiento, la modificación del comportamiento así como la adquisición de conocimientos y habilidades.

  3. Evidence for Nuclear Control of the Expression of the atpA and atpB Chloroplast Genes in Chlamydomonas.

    Science.gov (United States)

    Drapier, D.; Girard-Bascou, J.; Wollman, F. A.

    1992-03-01

    We analyzed three nuclear mutants of Chlamydomonas reinhardtii altered in the expression of the chloroplast genes atpA or atpB coding for the [alpha] or [beta] subunit of the chloroplast ATP synthase. These mutants revealed the existence of three nuclear products controlling the expression of the two chloroplast genes: the first one acts on the translation of the atpA transcript, and the two others act specifically on the stability of either the atpB or the atpA mRNAs. The nuclear mutation responsible for the decreased stability of the atpB mRNA prevented translation of the corresponding polypeptide. In contrast, the mutation responsible for the decreased stability of the atpA mRNA had limited effect on the translation of the [alpha] subunit, thereby allowing its accumulation and assembly in an active ATP synthase. Although acting originally on the expression of only one of the two main coupling factor 1 subunits, the three mutations caused a change in the translation rate of the other subunit, as viewed in 5-min pulse labeling experiments. This is indicative of a concerted expression of the [alpha] and [beta] subunits at an early post-translational step, or during translation, that may be critical for the assembly of the chloroplast ATP synthase.

  4. Human factors design, verification, and validation for two types of control room upgrades at a nuclear power plant

    Energy Technology Data Exchange (ETDEWEB)

    Boring, Laurids Ronald [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2014-10-01

    This paper describes the NUREG-0711 based human factors engineering (HFE) phases and associated elements required to support design, verification and validation (V&V), and implementation of a new plant process computer (PPC) and turbine control system (TCS) at a representative nuclear power plant. This paper reviews ways to take a human-system interface (HSI) specification and use it when migrating legacy PPC displays or designing displays with new functionality. These displays undergo iterative usability testing during the design phase and then undergo an integrated system validation (ISV) in a full scope control room training simulator. Following the successful demonstration of operator performance with the systems during the ISV, the new system is implemented at the plant, first in the training simulator and then in the main control room.

  5. An Investigation for Arranging the Video Display Unit Information in a Main Control Room of Advanced Nuclear Power Plants

    Energy Technology Data Exchange (ETDEWEB)

    Hsu, Chong Cheng; Yang, Chih Wei [Institute of Nuclear Energy Research, Atomic Energy Council, Taoyuan (China)

    2014-08-15

    Current digital instrumentation and control and main control room (MCR) technology has extended the capability of integrating information from numerous plant systems and transmitting needed information to operations personnel in a timely manner that could not be envisioned when previous generation plants were designed and built. A MCR operator can complete all necessary operating actions on the video display unit (VDU). It is extremely flexible and convenient for operators to select and to control the system display on the screen. However, a high degree of digitalization has some risks. For example, in nuclear power plants, failures in the instrumentation and control devices could stop the operation of the plant. Human factors engineering (HFE) approaches would be a manner to solve this problem. Under HFE considerations, there exists 'population stereotype' for operation. That is, the operator is used to operating a specific display on the specific VDU for operation. Under emergency conditions, there is possibility that the operator will response with this habit population stereotype, and not be aware that the current situation has already changed. Accordingly, the advanced nuclear power plant should establish the MCR VDU configuration plan to meet the consistent teamwork goal under normal operation, transient and accident conditions. On the other hand, the advanced nuclear power plant should establish the human factors verification and validation plan of the MCR VDU configuration to verify and validate the configuration of the MCR VDUs, and to ensure that the MCR VDU configuration allows the operator shift to meet the HFE consideration and the consistent teamwork goal under normal operation, transient and accident conditions. This paper is one of the HF V V plans of the MCR VDU configuration of the advanced nuclear power plant. The purpose of this study is to confirm whether the VDU configuration meets the human factors principles and the consistent

  6. Nuclear pore complex remodeling by p75NTR cleavage controls TGF-β signaling and astrocyte functions

    Science.gov (United States)

    Schachtrup, Christian; Ryu, Jae Kyu; Mammadzada, Könül; Khan, Abdullah S.; Carlton, Peter M.; Perez, Alex; Christian, Frank; Le Moan, Natacha; Vagena, Eirini; Baeza-Raja, Bernat; Rafalski, Victoria; Chan, Justin P.; Nitschke, Roland; Houslay, Miles D.; Ellisman, Mark H.; Wyss-Coray, Tony; Palop, Jorge J.; Akassoglou, Katerina

    2016-01-01

    Astrocytes play critical roles in neuronal activity and inhibition of regeneration. Here we show that the cleaved p75 neurotrophin receptor (p75NTR) is a component of the nuclear pore complex (NPC) required for glial scar formation and reduced gamma oscillations in mice via regulation of TGF-β signaling. The cleaved p75NTR interacts with nucleoporins to promote Smad2 nucleocytoplasmic shuttling. Thus, NPC remodeling by regulated intramembrane cleavage of p75NTR controls astrocyte-neuronal communication in response to profibrotic factors. PMID:26120963

  7. Implementation of a quality control program of the equipment of the nuclear medicine services in Chile; Implementacion de un programa de control de calidad del equipamiento de los servicios de medicina nuclear de Chile

    Energy Technology Data Exchange (ETDEWEB)

    Astudillo, R.; Diaz, G.; Ferreira, A.; Garcia, M.; Hermosilla, A.; Pacheco, F.; Vasquez, M. [Universidad de la Frontera, Departamento de Ciencias Fisicas, Av. Francisco Salazar 1145, Temuco 4811230, Araucania (Chile); Coca, M., E-mail: ferreira.sdgr@gmail.com [MedScan Concepcion, Paicavi 270, Concepcion (Chile)

    2014-08-15

    Now days in Chile there are more of 43 Nuclear Medicine centers; most of them have gamma cameras in order to study physiological process in diagnostic and treatment of patients pathologies. This requires having the equipment in optimal operating condition and it is ensured with quality control programs that are based on a series of tests relating to protocols, such as TECDOC-602 y AAPM No.6. Planar test often applied in gamma cameras including: spatial resolution, spatial linearity, sensitivity and uniformity. SPECT tests consider: tomography uniformity, rotation center tomography resolution and total performance. The tests in dose calibrator are: background measurement, accuracy, precision, linearity and reproducibility. The tests above require the use of radioactive sources and specific simulators patterns or phantom based on international standards such as The National Electrical Manufacturers Association (Nema), International Atomic Energy Agency (IAEA) and The American Association of Medical Physics (AAPM). In this work we carried out several tests of quality control in a Nuclear Medicine Center of Temuco and we propose to implement the applied methodology in others similar Chilean centers. (author)

  8. An analysis of Technical Security Control Requirements For Digital I and C Systems in Nuclear Power Plants

    Energy Technology Data Exchange (ETDEWEB)

    Song, Jaegu; Lee, Jungwoon; Park, Geeyong; Kwon, Keechoon; Lee, Dongyoung; Lee, Cheolkwon [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2013-10-15

    Instrumentation and control systems in nuclear power plants have been digitalized for the purpose of maintenance and precise operation. This digitalization, however, brings out issues related to cyber security. In the most recent past, international standard organizations, regulatory institutes, and research institutes have performed a number of studies addressing these systems cyber security. In order to provide information helpful to the system designers in their application of cyber security for the systems, this paper presents methods and considerations to define attack vectors in a target system, to review and select the requirements in the Regulatory Guide 5.71, and to integrate the results to identify applicable technical security control requirements. In this study, attack vectors are analyzed through the vulnerability analyses and penetration tests with a simplified safety system, and the elements of critical digital assets acting as attack vectors are identified. Among the security control requirements listed in Appendices B and C to Regulatory Guide 5.71, those that should be implemented into the systems are selected and classified in groups of technical security control requirements using the results of the attack vector analysis. For the attack vector elements of critical digital assets, all the technical security control requirements are evaluated to determine whether they are applicable and effective, and considerations in this evaluation are also discussed. The technical security control requirements in three important categories of access control, monitoring and logging, and encryption are derived and grouped according to the elements of attack vectors as results for the sample safety system.

  9. Las agencias de viaje virtuales: ¿Cómo analizar la calidad de e-servicio y sus efectos sobre la satisfacción del cliente?

    Directory of Open Access Journals (Sweden)

    Rodolfo Vázquez-Casielles

    2009-01-01

    Full Text Available La forma de hacer negocios en la industria turística ha cambiado dramáticamente debido al desarrollo de las tecnologías de la información. El negocio de las reservas online en el mercado español mueve en torno a 5.800 millones de euros y las agencias de viajes virtuales (AVV abarcan la tercera parte del total de esta facturación. En este contexto, la competencia de las AVV es cada vez más intensa y resulta fundamental comprender la calidad de e-servicio percibida por sus clientes. El objetivo de este artículo es identificar las dimensiones de calidad de servicio recibida a través de la web y su influencia sobre la satisfacción del turista potencial. Asimismo, también se analizan las fortalezas y las debilidades de las AVV con respecto a dichas dimensiones con el fin de orientar el diseño de su oferta.

  10. Basis for and practical methods of controlling painting activities at the Sequoyah Nuclear Plant

    Energy Technology Data Exchange (ETDEWEB)

    Campbell, R.R. [Tennessee Valley Authority, Chattanooga, TN (United States)

    1997-08-01

    Sequoyah Nuclear Plant (SQN) follows the guidance presented in Regulatory Guide (R.G.) 1.52, {open_quotes}Design, Testing, and Maintenance Criteria for Atmospheric Cleanup System Air Filtration and Adsorption System Units of Light-Water-Cooled Nuclear Power Plants{close_quotes} in protecting its charcoal filter trains from the effects of painting and other chemical releases. SQN, as well as other nuclear facilities around the country, have the problem of how to address the issue of protection of Engineered Safety Feature (ESF) filter systems from degradation due to communication with airborne hydrocarbons (i.e., primarily paints and solvents). R.G. 1.52 (and a similar statement from R.G. 1.140) states in part,{open_quotes}Testing should be performed ... following painting, fire, or chemical release in any ventilation zone communicating with the system...,{close_quotes} and requires that a test be performed upon any kind of painting or chemical release. This is considered overly restrictive if the activity is minor and in a location remote from the charcoal filters. Charcoal filters used in air cleaning systems are required to filter out radioactive iodine from an airstream before its release from the plant to the environment. Charcoal filters will age with time because of their ability to adsorb many different types of material. This aging affects the charcoal by lowering its iodine retention efficiency, and therefore the charcoal needs to be protected from the effects of chemicals such as paint fumes. 14 refs., 3 tabs.

  11. Microscopic control of $^{29}$Si nuclear spins near phosphorus donors in silicon

    CERN Document Server

    Järvinen, J; Ahokas, J; Sheludyakov, S; Vainio, O; Lehtonen, L; Vasiliev, S; Fujii, Y; Mitsudo, S; Mizusaki, T; Gwak, M; Lee, SangGap; Lee, Soonchil; Vlasenko, L

    2014-01-01

    Dynamic nuclear polarization of $^{29}$Si nuclei in resolved lattice sites near the phosphorus donors in natural silicon of has been created using the Overhauser and solid effects. Polarization has been observed as a pattern of well separated holes and peaks in the electron spin resonance line of the donor. The Overhauser effect in ESR hole burning experiments was used to manipulate the polarization of $^{29}$Si spins at ultra low (100-500 mK) temperatures and in high magnetic field of 4.6 T. Extremely narrow holes of 15 mG width were created after several seconds of pumping.

  12. Geometric optimal control of the contrast imaging problem in Nuclear Magnetic Resonance

    CERN Document Server

    Bonnard, B; Glaser, S J; Lapert, M; Sugny, D; Zhang, Y

    2012-01-01

    The objective of this article is to introduce the tools to analyze the contrast imaging problem in Nuclear Magnetic Resonance. Optimal trajectories can be selected among extremal solutions of the Pontryagin Maximum Principle applied to this Mayer type optimal problem. Such trajectories are associated to the question of extremizing the transfer time. Hence the optimal problem is reduced to the analysis of the Hamiltonian dynamics related to singular extremals and their optimality status. This is illustrated by using the examples of cerebrospinal fluid / water and grey / white matter of cerebrum.

  13. The development of advanced robotic technology. A study on the tele-existence and intelligent control of a robot system for nuclear power plants

    Energy Technology Data Exchange (ETDEWEB)

    Chung, Myung Jin; Byun, Jueng Nam; Kim, Jong Hwan; Lee, Ju Jang; Bang, Seok Won; Chu, Gil Hwan; Park, Jong Cheol; Choi, Jong Seok; Yang, Jung Min; Hong, Sun Ki [Korea Advanced Institute of Science and Technology, Taejon (Korea, Republic of)

    1995-07-01

    To increase the efficiency of human intelligence it is required to develop an intelligent monitoring and system. In this research, we develop intelligent control methods related with tele-operation, tele-existence, real-time control technique, and intelligent control technique. Those are key techniques in tele-operation, especially for the repair and maintenance of nuclear power plants. The objective of this project is to develop of the tele-existence and intelligent control system for a robot used in the nuclear power plants. (author). 20 refs.

  14. Asociación entre la capacidad de la agencia de autocuidado y la adherencia a tratamientos farmacológicos y no farmacológicos en personas con alguna condición de enfermedad coronaria

    Directory of Open Access Journals (Sweden)

    CLARA VICTORIA BASTIDAS SÁNCHEZ

    2007-12-01

    Full Text Available El propósito del estudio con un diseño descriptivo, transversal y correlacional- fue explorar la relación entre agencia de autocuidado y adherencia en 115 pacientes con enfermedad coronaria seleccionados intencionalmente de una población de pacientes coronarios que asistieron a la consulta de cardiología en una clínica de la ciudad de Ibagué durante cuatro meses del año 2005. Se midió la capacidad de la agencia con el instrumento Evaluación de la Capacidad de la Agencia de Autocuidado, validado en su versión al español, y se calculó la adherencia a tratamientos farmacológicos y no farmacológicos en el mismo grupo mediante una escala que corresponde al resultado de adherencia y sus indicadores de la taxonomía NOC acompañada de una guía de valoración. Esa escala traducida al español fue evaluada en su comprensión por un grupo de enfermeras con experiencia clínica y docente en el área. El perfil clínico del grupo consistió en tres grupos, de acuerdo con la complejidad del régimen de medicamentos: 24, 58, 911 y de la condición de la enfermedad coronaria con tratamiento convencional, enfermedad coronaria con tratamiento intervencionista y pacientes con falla coronaria. Mediante pruebas de correlación tipo Pearson se pudo confirmar una asociación moderadamente positiva entre la capacidad de la agencia de autocuidado y la adherencia a tratamientos farmacológicos y no farmacológicos, aspecto este que se había sugerido al proponer el estudio; es decir que la adherencia y la capacidad de la agencia de autocuidado son comportamientos positivos que están presentes con características similares en personas con enfermedad coronaria como las de esta muestra. Se confirmó que la complejidad del régimen terapéutico tiene influencia en la adherencia, aun cuando en este grupo solo se mostró en una manera leve pero positiva, concordante con lo encontrado en otros estudios reportados por la OMS.

  15. A model for the control of DNA integrity by the sperm nuclear matrix

    Directory of Open Access Journals (Sweden)

    Joanna E Gawecka

    2015-01-01

    Full Text Available The highly condensed chromatin of mammalian spermatozoa is usually considered to be biologically inert before fertilization. However, we have demonstrated that even in this compacted state, sperm chromatin is subject to degradation at open configurations associated with the nuclear matrix through a process we have termed sperm chromatin fragmentation (SCF. This suggests that a mechanism exists to monitor the health of spermatozoa during transit through the male reproductive tract and to destroy the genome of defective sperm cells. The site of DNA damage in SCF, the matrix attachment sites, are the same that we hypothesize initiate DNA synthesis in the zygote. When sperm that have damaged DNA are injected into the oocyte, the newly created zygote responds by delaying DNA synthesis in the male pronucleus and, if the damage is severe enough, arresting the embryo′s development. Here we present a model for paternal DNA regulation by the nuclear matrix that begins during sperm maturation and continues through early embryonic development.

  16. Electron dynamics upon ionization: Control of the timescale through chemical substitution and effect of nuclear motion

    Energy Technology Data Exchange (ETDEWEB)

    Vacher, Morgane; Bearpark, Michael J.; Robb, Michael A. [Department of Chemistry, Imperial College London, London SW7 2AZ (United Kingdom); Mendive-Tapia, David [Laboratoire CEISAM - UMR CNR 6230, Université de Nantes, 2 Rue de la Houssinière, BP 92208, 44322 Nantes Cedex 3 (France)

    2015-03-07

    Photoionization can generate a non-stationary electronic state, which leads to coupled electron-nuclear dynamics in molecules. In this article, we choose benzene cation as a prototype because vertical ionization of the neutral species leads to a Jahn-Teller degeneracy between ground and first excited states of the cation. Starting with equal populations of ground and first excited states, there is no electron dynamics in this case. However, if we add methyl substituents that break symmetry but do not radically alter the electronic structure, we see charge migration: oscillations in the spin density that we can correlate with particular localized electronic structures, with a period depending on the gap between the states initially populated. We have also investigated the effect of nuclear motion on electron dynamics using a complete active space self-consistent field (CASSCF) implementation of the Ehrenfest method, most previous theoretical studies of electron dynamics having been carried out with fixed nuclei. In toluene cation for instance, simulations where the nuclei are allowed to move show significant differences in the electron dynamics after 3 fs, compared to simulations with fixed nuclei.

  17. CREB controls hepatic lipid metabolism through nuclear hormone receptor PPAR-gamma.

    Science.gov (United States)

    Herzig, Stephan; Hedrick, Susan; Morantte, Ianessa; Koo, Seung-Hoi; Galimi, Francesco; Montminy, Marc

    2003-11-13

    Fasting triggers a series of hormonal cues that promote energy balance by inducing glucose output and lipid breakdown in the liver. In response to pancreatic glucagon and adrenal cortisol, the cAMP-responsive transcription factor CREB activates gluconeogenic and fatty acid oxidation programmes by stimulating expression of the nuclear hormone receptor coactivator PGC-1 (refs 2-5). In parallel, fasting also suppresses lipid storage and synthesis (lipogenic) pathways, but the underlying mechanism is unknown. Here we show that mice deficient in CREB activity have a fatty liver phenotype and display elevated expression of the nuclear hormone receptor PPAR-gamma, a key regulator of lipogenic genes. CREB inhibits hepatic PPAR-gamma expression in the fasted state by stimulating the expression of the Hairy Enhancer of Split (HES-1) gene, a transcriptional repressor that is shown here to be a mediator of fasting lipid metabolism in vivo. The coordinate induction of PGC-1 and repression of PPAR-gamma by CREB during fasting provides a molecular rationale for the antagonism between insulin and counter-regulatory hormones, and indicates a potential role for CREB antagonists as therapeutic agents in enhancing insulin sensitivity in the liver.

  18. Evaluation of training programs and entry-level qualifications for nuclear-power-plant control-room personnel based on the systems approach to training

    Energy Technology Data Exchange (ETDEWEB)

    Haas, P M; Selby, D L; Hanley, M J; Mercer, R T

    1983-09-01

    This report summarizes results of research sponsored by the US Nuclear Regulatory Commission (NRC) Office of Nuclear Regulatory Research to initiate the use of the Systems Approach to Training in the evaluation of training programs and entry level qualifications for nuclear power plant (NPP) personnel. Variables (performance shaping factors) of potential importance to personnel selection and training are identified, and research to more rigorously define an operationally useful taxonomy of those variables is recommended. A high-level model of the Systems Approach to Training for use in the nuclear industry, which could serve as a model for NRC evaluation of industry programs, is presented. The model is consistent with current publically stated NRC policy, with the approach being followed by the Institute for Nuclear Power Operations, and with current training technology. Checklists to be used by NRC evaluators to assess training programs for NPP control-room personnel are proposed which are based on this model.

  19. Material control in nuclear fuel fabrication facilities. Part II. Accountability, instrumentation and measurement techniques in fuel fabrication facilities

    Energy Technology Data Exchange (ETDEWEB)

    Borgonovi, G.M.; McCartin, T.J.; McDaniel, T.; Miller, C.L.; Nguyen, T.

    1978-01-01

    This report describes the measurement techniques, the instrumentation, and the procedures used in accountability and control of nuclear materials, as they apply to fuel fabrication facilities. A general discussion is given of instrumentation and measurement techniques which are presently used being considered for fuel fabrication facilities. Those aspects which are most significant from the point of view of satisfying regulatory constraints have been emphasized. Sensors and measurement devices have been discussed, together with their interfacing into a computerized system designed to permit real-time data collection and analysis. Estimates of accuracy and precision of measurement techniques have been given, and, where applicable, estimates of associated costs have been presented. A general description of material control and accounting is also included. In this section, the general principles of nuclear material accounting have been reviewed first (closure of material balance). After a discussion of the most current techniques used to calculate the limit of error on inventory difference, a number of advanced statistical techniques are reviewed. The rest of the section deals with some regulatory aspects of data collection and analysis, for accountability purposes, and with the overall effectiveness of accountability in detecting diversion attempts in fuel fabrication facilities. A specific example of application of the accountability methods to a model fuel fabrication facility is given. The effect of random and systematic errors on the total material uncertainty has been discussed, together with the effect on uncertainty of the length of the accounting period.

  20. How reliable is the mean-field nuclear matter description for supporting chiral effective lagrangians?

    CERN Document Server

    Delfino, A; Frederico, T

    1996-01-01

    The link between non-linear chiral effective Lagrangians and the Walecka model description of bulk nuclear matter [1] is questioned. This fact is by itself due to the Mean Field Approximation (MFA) which in nuclear mater makes the picture of a nucleon-nucleon interaction based on scalar(vector) meson exchange, equivalent to the description of a nuclear matter based on attractive and repulsive contact interactions. We present a linear chiral model where this link between the Walecka model and an underlying to chiral symmetry realization still holds, due to MFA.

  1. Interactions between mRNA export commitment, 3'-end quality control, and nuclear degradation

    DEFF Research Database (Denmark)

    Libri, Domenico; Dower, Ken; Boulay, Jocelyne;

    2002-01-01

    elongation. Indeed, we find that a pool of heat shock HSP104 transcripts are 3'-end truncated in THO complex mutant as well as sub2 mutant backgrounds. Surprisingly, however, this defect can be suppressed by deletion of the 3'-5' exonuclease Rrp6p. This indicates that incomplete RNAs result from nuclear...... that the failure to retain and/or degrade defective mRNAs is deleterious. mRNAs produced in the 3'-end processing mutants rna14-3 and rna15-2, as well as an RNA harboring a 3' end generated by a self-cleaving hammerhead ribozyme, are also retained in Rrp6p-dependent transcription site foci. Taken together, our...

  2. Nociceptive behaviors were induced by electrical stimulation of the dura mater surrounding the superior sagittal sinus in conscious adult rats and reduced by morphine and rizatriptan benzoate.

    Science.gov (United States)

    Dong, Zhao; Jiang, Lei; Wang, Xiaohui; Wang, Xiaolin; Yu, Shengyuan

    2011-01-12

    The trigeminovascular nociception induced by electrical stimulation of the dura mater surrounding the superior sagittal sinus in anesthetized animals has been widely used as a model for investigation of the pathophysiology of vascular headache such as migraine. However, little is known whether pain behaviors can be induced using this model in conscious animals. Thus, to establish a new model of trigeminovascular nociception in conscious animals and to examine the effects of morphine and rizatriptan benzoate on nociceptive behaviors in this new model, we electrically stimulated the dura mater surrounding the superior sagittal sinus. We found that grooming and head-flick activities were altered partially in a frequency-dependent way and that frequencies ranging from 10 to 20 Hz more easily provoked these behaviors. Moreover, we also demonstrated that these behaviors were reduced by morphine and rizatriptan benzoate. Thus, this new model will provide a useful and appropriate tool to directly assess changes in the intensity of pain for further investigation of pathophysiological mechanisms of migraine in conscious animals.

  3. Phylogenetic relationships of Australian and New Zealand feral pigs assessed by mitochondrial control region sequence and nuclear GPIP genotype.

    Science.gov (United States)

    Gongora, Jaime; Fleming, Peter; Spencer, Peter B S; Mason, Richard; Garkavenko, Olga; Meyer, Johann-Nikolaus; Droegemueller, Cord; Lee, Jun Heon; Moran, Chris

    2004-11-01

    Pigs were introduced into Australia and New Zealand in the 18th and 19th centuries, with some establishing feral populations. With few records of pig introductions into these two countries, molecular phylogenetic analysis was used to assess their origins. Mitochondrial (mt) control region sequence and nuclear glucosephosphate isomerase pseudogene (GPIP) restriction fragments were used, as distinct European and Asian domestic pig and Wild Boar control region clades and GPIP genotypes can be recognised. Feral pig control region sequences clustered with either European or Asian domestic pig sequences and both Asian and European GPIP alleles were segregating. It was not possible to distinguish direct importation of Asian domestic animals into Australia and New Zealand from indirect introgression of Asian domestic sequences via Europe. However, the clustering of three feral control region sequences of pigs from northern Australia with Asian Wild Boar implies unrecorded introduction of Wild Boar or crossbred animals into Australia. However, two of these feral pigs had European GPIP alleles. In combination, analyses of control region and GPIP markers suggest that both European and Asian pigs have contributed in similar frequencies to the origins of Australian feral pigs.

  4. Report on nuclear installations safety and security control. Rapport sur le controle de la surete et de la securite des installations nucleaires. Surete des installations. Securite et information

    Energy Technology Data Exchange (ETDEWEB)

    Birraux, C.; Serusclat, F.

    1990-01-01

    This report of the parliamentary office for evaluation of scientific and technological choices bearing on the safety and security of nuclear installations is divided into 2 volumes bearing on: - Volume I: nuclear installations safety. - nuclear safety and international organizations. - works separation: Finland, Belgium and Federal Republic of Germany. - French organization. - Volume II: security and information. - French nuclear security. - Public information.

  5. The Relationship between Nuclear Disarmament and Nuclear Nonproliferation

    Institute of Scientific and Technical Information of China (English)

    Sun; Xiangli

    2015-01-01

    The history of nuclear weapons development since the end of World War II is also one of nuclear arms control.There are two major aspects that represent the global efforts of nuclear arms control,which include limiting on nuclear weapon development in quantities and qualities,and limiting on the proliferation of nuclear weapons and the relevant research and development technologies.The limitation on the nuclear weapons development constitute

  6. Investigation on the use digital controls instead of PID analog controls in the level control of steam generators of nuclear power PWR; Investigacao sobre o uso de controladores digitais em substituicao aos controladores analogicos PID para o controle de nivel de geradores de vapor de centrais nucleares PWR

    Energy Technology Data Exchange (ETDEWEB)

    Alvarenga, Marco Antonio Bayout

    2012-07-01

    The aim of this study is to identify current alternatives for the implementation of digital controllers in the level control of steam generators of nuclear power PWR (Pressurized Water Reaetor). It is intended to identify the types of digital controls that are available from the theoretical and conceptual viewpoints for this purpose. We investigate the advantages and disadvantages of each controller model. From this assessment are pointed the most suitable models in hierarchical scale. This evaluation also serves to suggest possible types of control installation as a whole, where the level control of the steam generators becomes just one of many controls that are part of the plant. In this case, the use of digital controls allows the non-linear and multivariable treatment which is characteristic of complex systems, such as the nuclear power generation. The treatment of nonlinearities and multivariable aspects allows a more detailed study of the stability of these plants when they are subject to transients or several accidents, such as the case of losing external power of transients. In the specific case of steam generators, the instabilities result from the emergence of the shrink and swell phenomenas, depending on the load variations of thermonuclear plant. The application of several types and digital controllers, considering these inherent characteristics of the level control of steam generators, allows to infer which types of controllers are more appropriate to treat instabilities of this type and to make conjectures in its use for the cases of more complex instabilities, considering the integration of all nucleus-plant controls.

  7. Nonlinear Control of Beam Halo-Chaos in Accelerator-Driven Clean Nuclear Power System

    Institute of Scientific and Technical Information of China (English)

    FANG JinQing; CHEN GuanRong; ZHOU LiuLai; WENG JiaQiang

    2002-01-01

    Beam halo-chaos in high-current accelerators has become a key concerned issue because it can cause excessive radioactivity from the accelerators therefore significantly limits their applications in industry, medicine, and national defense. Some general engineering methods for chaos control have been developed in recent years, but they generally are unsuccessful for beam halo-chaos suppression due to many technical constraints. Beam halo-chaos is essentially a spatiotemporal chaotic motion within a high power proton accelerator. In this paper, some efficient nonlinear control methods, including wavelet function feedback control as a special nonlinear control method, are proposed for controlling beam halo-chaos under five kinds of the initial proton beam distributions (i.e., Kapchinsky-Vladimirsky, full Gauss,3-sigma Gauss, water-bag, and parabola distributions) respectively. Particles-in-cell simulations show that after control of beam halo-chaos, the beam halo strength factor is reduced to zero, and other statistical physical quantities of beam halo-chaos are doubly reduced. The methods we developed is very effective for suppression of proton beam halo-chaos in a periodic focusing channel of accelerator. Some potential application of the beam halo-chaos control in experiments is finally pointed out.

  8. Individual dose monitoring of the nuclear medicine departments staff controlled by Central Laboratory for Radiological Protection.

    Science.gov (United States)

    Szewczak, Kamil; Jednoróg, Sławomir; Krajewski, Paweł

    2013-01-01

    Presented paper describes the results of the individual doses measurements for ionizing radiation, carried out by the Laboratory of Individual and Environmental Doses Monitoring (PDIS) of the Central Laboratory for Radiological Protection in Warsaw (CLOR) for the medical staff employees in several nuclear medicine (NM) departments across Poland. In total there are48 NM departments in operation in Poland [1] (consultation in Nuclear Atomic Agency). Presented results were collected over the period from January 2011 to December 2011 at eight NM departments located in Krakow, Warszawa (two departments), Rzeszow (two departments), Opole, Przemysl and Gorzow Wielkopolski. For radiation monitoring three kinds of thermo luminescence dosimeters (TLD) were used. The first TLD h collected information about whole body (C) effective dose, the second dosimeter was mounted in the ring (P) meanwhile the third on the wrist (N) of the tested person. Reading of TLDs was performed in quarterly periods. As a good approximation of effective and equivalent dose assessment of operational quantities both the individual dose equivalent Hp(10) and the Hp(0.07) were used. The analysis of the data was performed using two methods The first method was based on quarterly estimations of Hp(10)q and Hp(0.07)q while the second measured cumulative annual doses Hp(10)a and Hp(0.07)a. The highest recorded value of the radiation dose for quarterly assessments reached 24.4 mSv and was recorded by the wrist type dosimeter worn by a worker involved in source preparation procedure. The mean values of Hp(10)q(C type dosimeter) and Hp(0.07)q (P and N type dosimeter) for all monitored departments were respectively 0.46 mSv and 3.29 mSv. There was a strong correlation between the performed job and the value of the received dose. The highest doses always were absorbed by those staff members who were involved in sources preparation. The highest annual cumulative dose for a particular worker in the considered time

  9. AN ANALYSIS OF TECHNICAL SECURITY CONTROL REQUIREMENTS FOR DIGITAL I&C SYSTEMS IN NUCLEAR POWER PLANTS

    Directory of Open Access Journals (Sweden)

    JAE-GU SONG

    2013-10-01

    Full Text Available Instrumentation and control systems in nuclear power plants have been digitalized for the purpose of maintenance and precise operation. This digitalization, however, brings out issues related to cyber security. In the most recent past, international standard organizations, regulatory institutes, and research institutes have performed a number of studies addressing these systems cyber security. In order to provide information helpful to the system designers in their application of cyber security for the systems, this paper presents methods and considerations to define attack vectors in a target system, to review and select the requirements in the Regulatory Guide 5.71, and to integrate the results to identify applicable technical security control requirements. In this study, attack vectors are analyzed through the vulnerability analyses and penetration tests with a simplified safety system, and the elements of critical digital assets acting as attack vectors are identified. Among the security control requirements listed in Appendices B and C to Regulatory Guide 5.71, those that should be implemented into the systems are selected and classified in groups of technical security control requirements using the results of the attack vector analysis. For the attack vector elements of critical digital assets, all the technical security control requirements are evaluated to determine whether they are applicable and effective, and considerations in this evaluation are also discussed. The technical security control requirements in three important categories of access control, monitoring and logging, and encryption are derived and grouped according to the elements of attack vectors as results for the sample safety system.

  10. Mitochondrial calcium uniporter Mcu controls excitotoxicity and is transcriptionally repressed by neuroprotective nuclear calcium signals.

    Science.gov (United States)

    Qiu, Jing; Tan, Yan-Wei; Hagenston, Anna M; Martel, Marc-Andre; Kneisel, Niclas; Skehel, Paul A; Wyllie, David J A; Bading, Hilmar; Hardingham, Giles E

    2013-01-01

    The recent identification of the mitochondrial Ca(2+) uniporter gene (Mcu/Ccdc109a) has enabled us to address its role, and that of mitochondrial Ca(2+) uptake, in neuronal excitotoxicity. Here we show that exogenously expressed Mcu is mitochondrially localized and increases mitochondrial Ca(2+) levels following NMDA receptor activation, leading to increased mitochondrial membrane depolarization and excitotoxic cell death. Knockdown of endogenous Mcu expression reduces NMDA-induced increases in mitochondrial Ca(2+), resulting in lower levels of mitochondrial depolarization and resistance to excitotoxicity. Mcu is subject to dynamic regulation as part of an activity-dependent adaptive mechanism that limits mitochondrial Ca(2+) overload when cytoplasmic Ca(2+) levels are high. Specifically, synaptic activity transcriptionally represses Mcu, via a mechanism involving the nuclear Ca(2+) and CaM kinase-mediated induction of Npas4, resulting in the inhibition of NMDA receptor-induced mitochondrial Ca(2+) uptake and preventing excitotoxic death. This establishes Mcu and the pathways regulating its expression as important determinants of excitotoxicity, which may represent therapeutic targets for excitotoxic disorders.

  11. The falsification of Chiral Nuclear Forces

    Science.gov (United States)

    Ruiz Arriola, E.; Amaro, J. E.; Navarro Perez, R.

    2017-03-01

    Predictive power in theoretical nuclear physics has been a major concern in the study of nuclear structure and reactions. The Effective Field Theory (EFT) based on chiral expansions provides a model independent hierarchy for many body forces at long distances but their predictive power may be undermined by the regularization scheme dependence induced by the counterterms and encoding the short distances dynamics which seem to dominate the uncertainties. We analyze several examples including zero energy NN scattering or perturbative counterterm-free peripheral scattering where one would expect these methods to work best and unveil relevant systematic discrepancies when a fair comparison to the Granada-2013 NN-database and partial wave analysis (PWA) is undertaken. Work supported by Spanish Ministerio de Economia y Competitividad and European FEDER funds (grant FIS2014-59386-P), the Agencia de Innovacion y Desarrollo de Andalucia (grant No. FQM225), the U.S. Department of Energy by Lawrence Livermore National Laboratory under Contract No. DE-AC52-07NA27344, U.S. Department of Energy, Office of Science, Office of Nuclear Physics under Award No. DE-SC0008511 (NUCLEI SciDAC Collaboration)

  12. Quantum control of the hyperfine-coupled electron and nuclear spins in alkali-metal atoms

    Science.gov (United States)

    Merkel, Seth T.; Jessen, Poul S.; Deutsch, Ivan H.

    2008-08-01

    We study quantum control of the full hyperfine manifold in the ground-electronic state of alkali-metal atoms based on applied radio frequency and microwave fields. Such interactions should allow essentially decoherence-free dynamics and the application of techniques for robust control developed for NMR spectroscopy. We establish the conditions under which the system is controllable in the sense that one can generate an arbitrary unitary map on the system. We apply this to the case of Cs133 with its d=16 dimensional Hilbert space of magnetic sublevels in the 6S1/2 state, and design control wave forms that generate an arbitrary target state from an initial fiducial state. We develop a generalized Wigner function representation for this space consisting of the direct sum of two irreducible representations of SU(2), allowing us to visualize these states. The performance of different control scenarios is evaluated based on the ability to generate a high-fidelity operation in an allotted time with the available resources. We find good operating points commensurate with modest laboratory requirements.

  13. Investigation of the impact of main control room digitalization on operators cognitive reliability in nuclear power plants.

    Science.gov (United States)

    Zhou, Yong; Mu, Haiying; Jiang, Jianjun; Zhang, Li

    2012-01-01

    Currently, there is a trend in nuclear power plants (NPPs) toward introducing digital and computer technologies into main control rooms (MCRs). Safe generation of electric power in NPPs requires reliable performance of cognitive tasks such as fault detection, diagnosis, and response planning. The digitalization of MCRs has dramatically changed the whole operating environment, and the ways operators interact with the plant systems. If the design and implementation of the digital technology is incompatible with operators' cognitive characteristics, it may have negative effects on operators' cognitive reliability. Firstly, on the basis of three essential prerequisites for successful cognitive tasks, a causal model is constructed to reveal the typical human performance issues arising from digitalization. The cognitive mechanisms which they impact cognitive reliability are analyzed in detail. Then, Bayesian inference is used to quantify and prioritize the influences of these factors. It suggests that interface management and unbalanced workload distribution have more significant impacts on operators' cognitive reliability.

  14. Virtual Visit to the ATLAS Control Room during Researchers Night by Institute of Nuclear Physics Polish Academy of Sciences, Cracow

    CERN Multimedia

    ATLAS Experiment

    2012-01-01

    We invite our "6-th Ma?opolska Researchers Night" guests for Virtual Visits in ATLAS Control Room. They could ask Polish scientists and experts during a lecture "How a mass is created - the Higgs boson discovery" to be given by dr Anna Kaczmarska. "Ma?opolska Researchers Night" is a part of European Researchers Night events to be held in more than 200 cities. Institute of Nuclear Physics Polish Academy of Sciences invites Cracow citizens and tourists visiting our town to its laboratories and to the "Science Garden" formed, especially for this event, in front of the main building. Visitors will have an unique opportunity to discuss science problems with researches and students. Wide range of demonstrations of interesting activities performed in our institute will be presented, these include among others: - AIC 144 Cyclotron with hadrons' therapy facility for eye treatment - Dosimetry and environmental pollution monitoring - Large Hadron Collider experiments - Van de Graff linear accelerator with proton micro b...

  15. Population structure of the African savannah elephant inferred from mitochondrial control region sequences and nuclear microsatellite loci

    DEFF Research Database (Denmark)

    Nyakaana, S; Arctander, P; Siegismund, H R

    2002-01-01

    Two hundred and thirty-six mitochondrial DNA nucleotide sequences were used in combination with polymorphism at four nuclear microsatellite loci to assess the amount and distribution of genetic variation within and between African savannah elephants. They were sampled from 11 localities in eastern...... populations and 44 alleles in the total sample were found. The gene diversity ranged from 0.51 to 0.72 in the localities studied. An analysis of molecular variance showed significant genetic differentiation between populations within regions and also between regions. The extent of subdivision between...... populations at the mtDNA control region was approximately twice as high as shown by the microsatellite loci (mtDNA F(ST) = 0.59; microsatellite R(ST) = 0.31). We discuss our results in the light of Pleistocene refugia and attribute the observed pattern to population divergence in allopatry accompanied...

  16. The Correlations of Educational Service,Perceived College Support and College Students’ Commitment to Alma Mater%大学生母校承诺的心理结构及其影响因素研究

    Institute of Scientific and Technical Information of China (English)

    陈志霞; 张敏

    2014-01-01

    母校承诺是指大学生对母校的心理认同和情感依恋,培养大学生对母校的积极情感,是大学生情感教育的重要构成部分。研究结果表明:大学生母校承诺的心理结构包含认知承诺、感情承诺和责任承诺三个部分,高校教育服务质量通过母校支持感的部分中介作用对大学生母校承诺发挥积极影响。因此,高校应从认知、情感和责任三维角度来加强对学生母校情感的综合培养,通过提高高校教育服务质量和学生的母校支持感进而增强其母校承诺。%Commitment to Alma Mater is a kind of psychological identification and emotional attachment for Alma Mater of college students. The structure and mechanism of college students ’ commitment to Alma Mater are analyzed through both theoretical analysis and empirical research. The results are as follows:Commitment to Alma Mater is composed of three factors:cognitive commitment,affective commitment and obligation commitment, and students’ perceived college support plays a partially intermediary role in the relationship between the quality of college’s education and service and college students’ commitment to Alma Mater. In order to improve college students ’ commitment to Alma Mater , colleges and universities should educate college students ’ affection to Alma Mater from cognitive,affective,responsible aspects and improve the commitment to Alma Mater through enhancing the quality of college’s education and service and the perceived college support.

  17. Orphan Nuclear Receptor ERRα Controls Macrophage Metabolic Signaling and A20 Expression to Negatively Regulate TLR-Induced Inflammation.

    Science.gov (United States)

    Yuk, Jae-Min; Kim, Tae Sung; Kim, Soo Yeon; Lee, Hye-Mi; Han, Jeongsu; Dufour, Catherine Rosa; Kim, Jin Kyung; Jin, Hyo Sun; Yang, Chul-Su; Park, Ki-Sun; Lee, Chul-Ho; Kim, Jin-Man; Kweon, Gi Ryang; Choi, Hueng-Sik; Vanacker, Jean-Marc; Moore, David D; Giguère, Vincent; Jo, Eun-Kyeong

    2015-07-21

    The orphan nuclear receptor estrogen-related receptor α (ERRα; NR3B1) is a key metabolic regulator, but its function in regulating inflammation remains largely unknown. Here, we demonstrate that ERRα negatively regulates Toll-like receptor (TLR)-induced inflammation by promoting Tnfaip3 transcription and fine-tuning of metabolic reprogramming in macrophages. ERRα-deficient (Esrra(-/-)) mice showed increased susceptibility to endotoxin-induced septic shock, leading to more severe pro-inflammatory responses than control mice. ERRα regulated macrophage inflammatory responses by directly binding the promoter region of Tnfaip3, a deubiquitinating enzyme in TLR signaling. In addition, Esrra(-/-) macrophages showed an increased glycolysis, but impaired mitochondrial respiratory function and biogenesis. Further, ERRα was required for the regulation of NF-κB signaling by controlling p65 acetylation via maintenance of NAD(+) levels and sirtuin 1 activation. These findings unravel a previously unappreciated role for ERRα as a negative regulator of TLR-induced inflammatory responses through inducing Tnfaip3 transcription and controlling the metabolic reprogramming.

  18. Leukaemia in young children in the vicinity of British nuclear power plants: a case–control study

    Science.gov (United States)

    Bithell, J F; Murphy, M F G; Stiller, C A; Toumpakari, E; Vincent, T; Wakeford, R

    2013-01-01

    Background: Concern about the risk of leukaemia in children living near nuclear power plants (NPPs) persists. Previous British analyses have been area based and consequently thought to be less effective than case–control studies. Methods: Cases of childhood leukaemia and non-Hodgkin lymphoma (LNHL) born and diagnosed in Great Britain between 1962 and 2007, with matched cancer-free controls, were analysed by logistic regression to estimate the risk of residential proximity at birth and diagnosis to the nearest NPP, adjusting for relevant variables. Results: For 9821 children with LNHL under the age of 5 years, the estimated extra risk associated with residential proximity to an NPP at birth was negative—interpolated Odds Ratio (OR) at 5 km was 0.86 (0.49–1.52). The comparison of 10 618 children with LNHL under five with 16 760 similarly aged children with other cancers also gave a negative estimate of the extra risk of residential proximity at diagnosis—interpolated OR at 5 km was 0.86 (0.62–1.18). Conclusion: Our results show little evidence of an increase in risk of LNHL to children aged under 5 years from living in the vicinity of an NPP. Risk estimates are incompatible with comparable ones published in a recent German case–control study. PMID:24030074

  19. 核电压力容器焊接过程中的生产管理%Production Control to Welding of Nuclear Reactor Pressure Vessels

    Institute of Scientific and Technical Information of China (English)

    宋桂艳

    2014-01-01

    The article describes the welding method for nuclear reactor pressure vessels and the key points of plan control and welding production control and process control in welding operation.%概述核电压力容器焊接的特点,指出焊接生产过程中计划管理、焊接生产过程管理和过程控制的重点内容。

  20. Automation inflicted differences on operator performance in nuclear power plant control rooms

    Energy Technology Data Exchange (ETDEWEB)

    Andersson, Jonas; Osvalder, A.L. [Chalmers Univ. of Technology, Dept. of Product and Producton Development (Sweden)

    2007-03-15

    Today it is possible to automate almost any function in a human-machine system. Therefore it is important to find a balance between automation level and the prerequisites for the operator to maintain safe operation. Different human factors evaluation methods can be used to find differences between automatic and manual operations that have an effect on operator performance; e.g. Predictive Human Error Analysis (PHEA), NASA Task Load Index (NASA-TLX), Halden Questionnaire, and Human Error Assessment and Reduction Technique (HEART). Results from an empirical study concerning automation levels, made at Ringhals power plant, showed that factors as time pressure and criticality of the work situation influenced the operator's performance and mental workload more than differences in level of automation. The results indicate that the operator's attention strategies differ between the manual and automatic sequences. Independently of level of automation, it is essential that the operator retains control and situational understanding. When performing a manual task, the operator is 'closer' to the process and in control with sufficient situational understanding. When the level of automation increases, the demands on information presentation increase to ensure safe plant operation. The need for control can be met by introducing 'control gates' where the operator has to accept that the automatic procedures are continuing as expected. Situational understanding can be established by clear information about process status and by continuous feedback. A conclusion of the study was that a collaborative control room environment is important. Rather than allocating functions to either the operator or the system, a complementary strategy should be used. Key parameters to consider when planning the work in the control room are time constraints and task criticality and how they affect the performance of the joint cognitive system.However, the examined working

  1. Technical evaluation of the electrical, instrumentation, and control design aspects of the low temperature overpressure protection system for the Point Beach Nuclear Power Plant, Units 1 and 2

    Energy Technology Data Exchange (ETDEWEB)

    Laudenbach, D.H.

    1979-03-01

    The technical evaluation is presented for the electrical, instrumentation, and control design aspects of the low temperature overpressure protection system for the Point Beach nuclear power plant, Units 1 and 2. Design basis criteria used to evaluate the acceptability of the system included operator action, system testability, single failure criterion, and seismic Category I and IEEE Std-279-1971 criteria. This report is supplied as part of the Selected Electrical, Instrumentation, and Control Systems Issues Support Program being conducted for the U.S. Nuclear Regulatory Commission by Lawrence Livermore Laboratory.

  2. Technical evaluation of the electrical, instrumentation, and control design aspects of the low temperature overpressure protection system for the Haddam Neck Nuclear Power Plant

    Energy Technology Data Exchange (ETDEWEB)

    Laudenbach, D.H.

    1979-03-01

    The technical evaluation of the electrical, instrumentation, and control design aspects of the low temperature overpressure protection system for the Haddam Neck Nuclear Power Plant is presented. Design basis criteria used to evaluate the acceptability of the system included operator action, system testability, single failure criterion, and seismic Category I and IEEE Std-279-1971 criteria. This report is supplied as part of the Selected Electrical, Instrumentation, and Control Systems Issues Support Program being conducted for the U.S. Nuclear Regulatory Commission by Lawrence Livermore Laboratory.

  3. Joint System Prognostics For Increased Efficiency And Risk Mitigation In Advanced Nuclear Reactor Instrumentation and Control

    Energy Technology Data Exchange (ETDEWEB)

    Donald D. Dudenhoeffer; Tuan Q. Tran; Ronald L. Boring; Bruce P. Hallbert

    2006-08-01

    The science of prognostics is analogous to a doctor who, based on a set of symptoms and patient tests, assesses a probable cause, the risk to the patient, and a course of action for recovery. While traditional prognostics research has focused on the aspect of hydraulic and mechanical systems and associated failures, this project will take a joint view in focusing not only on the digital I&C aspect of reliability and risk, but also on the risks associated with the human element. Model development will not only include an approximation of the control system physical degradation but also on human performance degradation. Thus the goal of the prognostic system is to evaluate control room operation; to identify and potentially take action when performance degradation reduces plant efficiency, reliability or safety.

  4. Pakistans Nuclear Weapons

    Science.gov (United States)

    2016-02-12

    Command and Control Support System, which “enables robust Command and Control capability of all strategic assets with round the clock situational...Building Confidence in Pakistan’s Nuclear Security,” Arms Control Today, December 2007; Robin Walker, “Pakistan’s Evolution as a Nuclear Weapons State: Lt...that understands the importance and the high priority that the world places on nuclear security. 136 Ambassador Olson told the House Foreign

  5. The Fos expression in rat brain following electrical stimulation of dura mater surrounding the superior sagittal sinus changed with the pre-treatment of rizatriptan benzoate.

    Science.gov (United States)

    Wang, Xiaolin; Yu, Shengyuan; Dong, Zhao; Jiang, Lei

    2011-01-07

    Fos expression in the brain was systematically investigated by means of immunohistochemical staining after electrical stimulation of the dura mater surrounding the superior sagittal sinus in conscious rats. Fos-like immunoreactive neurons are distributed mainly in the upper cervical spinal cord, spinal trigeminal nucleus caudal part, raphe magnus nucleus, periaqueductal gray, ventromedial hypothalamic nucleus, and mediodorsal thalamus nucleus. With the pre-treatment of intraperitoneal injection of rizatriptan benzoate, the number of Fos-like immunoreactive neurons decreased in the spinal trigeminal nucleus caudal part and raphe magnus nucleus, increased in the periaqueductal gray, and remained unchanged in the ventromedial hypothalamic nucleus and mediodorsal thalamus nucleus. These results provide morphological evidence that the nuclei described above are involved in the development and maintenance of the trigeminovascular headache.

  6. Realización del programa “Proyecto estratégico de seguridad alimentaria” por la Agencia de Desarrollo Rural innovaciones para el desarrollo competitivo S.C. : En el municipio de Maravilla Tenejapa (Chiapas, México)

    OpenAIRE

    Gil Jiménez, Karla Elizabeth; Aguilar López, Flor Magali

    2015-01-01

    La agroecología se opone a la reducción de la biodiversidad, uso de agroquímicos y se opone al desplazamiento del pequeño agricultor. En las últimas décadas, aumenta la conciencia sobre la necesidad de reorientar los sistemas de producción rural para convertirlos en modelos ecológicos de uso. Esto implica una nueva conciencia social, política de difusión y consolidación de los principios de la agroecología. En el año 2013, en el municipio de Maravilla Tenejapa, Chiapas, la Agencia de Desarrol...

  7. Estrategias para mejorar el desempeño laboral a través de incentivos y capacitación en los empleados de las agencias aduanales de la Delegación Gustavo A. Madero.

    OpenAIRE

    2015-01-01

    El presente trabajo de investigación propone una serie de estrategias con el fin de ayudar a los agentes aduanales de nuestro país a mejorar el desempeño laboral de los empleados que trabajan en sus agencias aduanales. La investigación realizada parte de 2 variables importantes mismas que fueron trabajadas a lo largo de la investigación:  Capacitación.  Incentivos. Factores que influyen como motivante para un buen desempeño laboral en los empleados de Silva Herzog Consorcio Aduanal...

  8. Capacidad de agencia de autocuidado en personas con hipertensión arterial de la fundación médico preventiva, san josé de cúcuta, 2004.

    OpenAIRE

    Peñaloza García, Mónica

    2012-01-01

    Estudio novedoso en la región, realizado por Enfermería con la finalidad de describir la Capacidad de Agencia de Autocuidado en personas con hipertensión arterial, pertenecientes al convenio de magisterio e inscritos en el programa de patologías crónicas de la Fundación Médico Preventiva, San José de Cúcuta, año 2004, según Teoría del Autocuidado planteada por Orem en 1993.Iinvestigación tipo descriptivo, abordaje cuantitativo y corte transversal, que obtuvo muestra de 77 individuos cum...

  9. Proceso de Evaluación de desempeño: análisis desde la teoría de la burocracia y de la agencia: estudios de caso del subsector hotelero en Medellín

    OpenAIRE

    Castaño Serna, Diana Marcela

    2014-01-01

    Resumen: Esta investigación tiene como objetivo principal estudiar el proceso de Evaluación de Desempeño y como se encuentra influenciado por la teoría de la burocracia y la teoría de la Agencia en el subsector hotelero de la ciudad de Medellín. El proceso de Evaluación de desempeño se considera de gran importancia para este subsector dado que el servicio que estos otorgan depende directamente del desempeño de los trabajadores y es lo que determina la satisfacción de los clientes, a partir de...

  10. Análisis descriptivo de los planes de investigación en pediatría resueltos por la Agencia Europea del Medicamento durante el periodo 2007-2009.

    OpenAIRE

    2011-01-01

    Análisis descriptivo de la información contenida en los Planes de Investigación Pediátricos (PIPs) resueltos por la Agencia Europea del Medicamento durante los años 2007-2009, para analizar tanto las características de los medicamentos que han presentado un PIP como las del propio plan de investigación. También se analizan los grupos terapéuticos a los que pertenecen los medicamentos incluidos en los PIPs, las edades de la población pediátrica incluidas en los PIPs y los estudios incluidos en...

  11. Nuclear disarmament verification

    Energy Technology Data Exchange (ETDEWEB)

    DeVolpi, A.

    1993-12-31

    Arms control treaties, unilateral actions, and cooperative activities -- reflecting the defusing of East-West tensions -- are causing nuclear weapons to be disarmed and dismantled worldwide. In order to provide for future reductions and to build confidence in the permanency of this disarmament, verification procedures and technologies would play an important role. This paper outlines arms-control objectives, treaty organization, and actions that could be undertaken. For the purposes of this Workshop on Verification, nuclear disarmament has been divided into five topical subareas: Converting nuclear-weapons production complexes, Eliminating and monitoring nuclear-weapons delivery systems, Disabling and destroying nuclear warheads, Demilitarizing or non-military utilization of special nuclear materials, and Inhibiting nuclear arms in non-nuclear-weapons states. This paper concludes with an overview of potential methods for verification.

  12. Instrumentation, control and data acquisition system with multiple configurations for test in nuclear environment

    Energy Technology Data Exchange (ETDEWEB)

    Monti, Chiara, E-mail: chiara.monti@enea.it; Neri, Carlo; Pollastrone, Fabio

    2015-10-15

    Highlights: • ENEA developed and characterized a first prototype of the In-Vessel Viewing System (IVVS) probe for ITER. • Piezo motor technology to be used in IVVS probe was tested in neutrons, gamma radiations, high temperature, vacuum and high magnetic fields. • A general architecture of the Data Acquisition and Control System (DACS) was defined and then specialized for each test. • The test campaign has validated instrumentation solutions, which can be effectively used in final IVVS implementation or other ITER diagnostics or applications. - Abstract: The In-Vessel Viewing System is a 3D laser scanning system which will be used to inspect the blanket first wall in ITER. To make the IVVS probe design compatible with the harsh environmental conditions present in ITER, a test campaign was performed in 2012–2013 to verify the adequacy of the main components of the IVVS probe. The IVVS components inspected were an optical encoder, passive components and two customized ultrasonic piezoceramic motors that were instrumented with various sensors. A general architecture of the Data Acquisition and Control System (DACS) was defined and then specialized for each test. To be suitable for this test campaign, the DACS had to host various I/O modules and to properly interface the driver of the customized piezo motors, in order to permit the full control of the test and the acquisition of experimental data. This paper presents the instrumentation solutions designed and implemented for different facilities constraints and the related DACS developed in four specialized versions for the described test campaign.

  13. Prediction of the lifetime of the elements of the safety and control rods of nuclear reactors

    Energy Technology Data Exchange (ETDEWEB)

    Voskoboinikov, V.V.; Emel' yanov, I. Ya.; Lineva, A.F.; Pushkin, S.N.; Semchenko, E.L.; Usov, P.P.

    1987-07-01

    The authors construct a mathematical model based on the analytical solution to such parameters as magnetic flux, alignment, sliding friction, erosion, abrasion, corrosion, and irradiation for the purpose of predicting the service life of electromagnetically driven control rods and their drives. The analytical solution was verified experimentally on a bench simulation where it was found that incorrect assembly and alignment not only serve as the largest contributors to shortened service life of the rods and drives but also render the calculations of the model invalid.

  14. Electron-Nuclear Dynamics in a Quantum Dot under Nonunitary Electron Control

    Science.gov (United States)

    2011-07-20

    Þ sin2 ! eTR 2 ; (8) where Se is the length of the electron steady-state SV and for brevity we have suppressed the superscript 1 [13]. The zero...of m such that ð!e þmAÞTR is an odd integer multiple of , and the locations of these peaks can be controlled by adjusting ! eTR . A systematic...q20 2q0 cos; ð1 q20Þ tanð! eTR =2Þ; q0! eTR sin; (11) where c is as in Ref. [15]. Nonzero x; y components arise from expanding the Overhauser

  15. Chloroplast biogenesis-associated nuclear genes: Control by plastid signals evolved prior to their regulation as part of photomorphogenesis.

    Directory of Open Access Journals (Sweden)

    Alison C HIlls

    2015-12-01

    Full Text Available The assembly of photosynthetically-competent chloroplasts occurs in angiosperm seedlings when first exposed to light, and is due to the control by light of photosynthesis-associated nuclear genes (PhANGs, also dependent upon plastid-to-nucleus biogenic communication signals. The relationship between light- and plastid signal-regulation of PhANGs is close but poorly understood. In contrast, many conifers green in the dark and the promoter of a pine PhANG, Lhcb, is active in the dark in tobacco. Here we show that the activity of this promoter in tobacco is sensitive to plastid photobleaching, or to the inhibition of plastid translation in the light or the dark, and the same interventions reduce expression of the native gene in pine seedlings, demonstrating classic plastid biogenic signalling in gymnosperms. Furthermore, Arabidopsis mutations causing defective plastid biogenesis suppress the effect in darkness of mutations in COP1 and DET1, repressors of photomorphogenesis, for the expression of several PhANGs but not a photosynthesis-unrelated, light-regulated gene. GLK transcriptional regulators mediate the response of LHCB but not of other tested PhANGs. We propose gain of the ability by repressors of photomorphogenesis to suppress the response of PhANG promoters to positive plastid biogenic signals in the dark to have contributed to the evolution of light control of chloroplast biogenesis.

  16. Inferring Invasion History of Red Swamp Crayfish (Procambarus clarkii in China from Mitochondrial Control Region and Nuclear Intron Sequences

    Directory of Open Access Journals (Sweden)

    Yanhe Li

    2015-06-01

    Full Text Available Identifying the dispersal pathways of an invasive species is useful for adopting the appropriate strategies to prevent and control its spread. However, these processes are exceedingly complex. So, it is necessary to apply new technology and collect representative samples for analysis. This study used Approximate Bayesian Computation (ABC in combination with traditional genetic tools to examine extensive sample data and historical records to infer the invasion history of the red swamp crayfish, Procambarus clarkii, in China. The sequences of the mitochondrial control region and the proPOx intron in the nuclear genome of samples from 37 sites (35 in China and one each in Japan and the USA were analyzed. The results of combined scenarios testing and historical records revealed a much more complex invasion history in China than previously believed. P. clarkii was most likely originally introduced into China from Japan from an unsampled source, and the species then expanded its range primarily into the middle and lower reaches and, to a lesser extent, into the upper reaches of the Changjiang River in China. No transfer was observed from the upper reaches to the middle and lower reaches of the Changjiang River. Human-mediated jump dispersal was an important dispersal pathway for P. clarkii. The results provide a better understanding of the evolutionary scenarios involved in the rapid invasion of P. clarkii in China.

  17. Personas con diabetes mellitus tipo 2 y su capacidad de agencia de autocuidado, Cartagena Pessoas com diabete mellitus tipo 2 e sua capacidade de agência de autocuidado, Cartagena Patients with Type 2 Mellitus Diabetes and their Self-Care Agency Capacity, Cartagena

    Directory of Open Access Journals (Sweden)

    Arleth Herrera Lían

    2012-07-01

    Full Text Available Contexto: La diabetes mellitus tipo 2 se constituye en un problema de salud pública por las repercusiones bio-psicosociales, la presencia de complicaciones neurovasculares y metabólicas en la persona que la padece. Enfermería cumple un papel importante a través de la educación y la capacitación. Objetivo: Identificar la capacidad de agencia de autocuidado de las personas con diagnóstico de diabetes mellitus tipo 2, inscritos en los programas de control de diabetes en 19 UPAS de Cartagena. Metodología: diseño descriptivo con abordaje cuantitativo, en una muestra de 225 adultos de ambos sexos, seleccionados en forma aleatoria. La capacidad de agencia de autocuidado se identificó con la escala de Valoración de las capacidades de autocuidado, desarrollada por Isenberg y Everest, traducida al español por Gallegos y adaptada por la Universidad Nacional de Colombia. Para presentar los datos se utilizó la estadística descriptiva, los resultados se presentan en tablas y gráficas. Resultados: Predominó el sexo femenino (68,4 %; la unión libre (59,1 %; escolaridad (50,6 % con básica primaria; bajos ingresos económicos (menos de un salario mínimo mensual vigente, 34.7 %. Al valorar la capacidad de agencia de autocuidado, el 73.8 % de los pacientes obtuvo una calificación de muy buena (76-100 %, según escala. Al valorar los aspectos comprendidos en la escala se encontró que más del 50 % de las personas siempre sacan tiempo para ellos, piden explicación sobre su salud, examinan su cuerpo para ver si hay cambios y conservan un ambiente limpio. Conclusiones: El apoyo social recibido por los pacientes con diabetes mellitus tipo 2 y las prácticas de higiene personal y del entorno, el conocimiento y la adherencia a la dieta, permiten a los pacientes una buena capacidad de agencia de autocuidado.Contexto: A diabete mellitus tipo 2 se configura como um problema de saúde pública por conta das repercussões biopsicossociais e da presen

  18. The Research of Project Schedule Plan and Control on UPS Design in Nuclear Island of Z Nuclear Power Plant%Z核电站核岛UPS设备设计进度计划及控制研究

    Institute of Scientific and Technical Information of China (English)

    林建

    2012-01-01

    采用工作分解结构分解了Z核电站核岛UPS设备设计项目,并用关键路径法编制了该项目进度,结合项目特点,基于PDCA控制流程对项目实施进度控制,确保项目顺利实施.%This paper uses work breakdown structure to break down the UPS design project in nuclear island of Z nuclear power plant, uses critical path method to build the schedule of the project, combined with the characteristics of the project, based on the PDCA control flow, controls the progress of project implementation and ensures the smooth implementation of the project.

  19. Fabrication of cermet bearings for the control system of a high temperature lithium cooled nuclear reactor

    Science.gov (United States)

    Yacobucci, H. G.; Heestand, R. L.; Kizer, D. E.

    1973-01-01

    The techniques used to fabricate cermet bearings for the fueled control drums of a liquid metal cooled reference-design reactor concept are presented. The bearings were designed for operation in lithium for as long as 5 years at temperatures to 1205 C. Two sets of bearings were fabricated from a hafnium carbide - 8-wt. % molybdenum - 2-wt. % niobium carbide cermet, and two sets were fabricated from a hafnium nitride - 10-wt. % tungsten cermet. Procedures were developed for synthesizing the material in high purity inert-atmosphere glove boxes to minimize oxygen content in order to enhance corrosion resistance. Techniques were developed for pressing cylindrical billets to conserve materials and to reduce machining requirements. Finishing was accomplished by a combination of diamond grinding, electrodischarge machining, and diamond lapping. Samples were characterized in respect to composition, impurity level, lattice parameter, microstructure and density.

  20. Modernization of the feedwater heaters control level of the Almaraz I Nuclear Power Plant by OVATION system; Modernizacion del control de nivel de los calentadores de agua de alimentacion de C.N. Almaraz I mediante el sistema OVATION

    Energy Technology Data Exchange (ETDEWEB)

    Madronal Rodriguez, E.; Cabrero Munoz, J. E.

    2010-07-01

    As a result of the process of technological renovation of the heaters system and the power increase project, Almaraz Nuclear Power Plant has made several design changes in the feedwater heaters system. Within these changes, the old heaters control loops are replaced because the new power will increase the heaters drainage caudal. This modernization is carried out using the OVATION control system.

  1. Quality control at the Regional Centre of Nuclear Sciences chemical dosimetry laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Souza, Vivianne L.B. de; Melo, Roberto T. de; Silva, Danubia B. da; Pedroza, Eryka H.; Rodrigues, Kelia R.G.; Cunha, Manuela S. da; Figueiredo, Marcela D.C. de [Centro Regional de Ciencias Nucleares (CRCN-NE/CNEN-PE), Recife, PE (Brazil); Oliveira, Aristides, E-mail: vlsouza@cnen.gov.b, E-mail: rtmelo@cnen.gov.b [Hospital de Cancer de Pernambuco, Recife, PE (Brazil)

    2011-07-01

    Standards for accreditation of laboratories as in ISO 9001 in section: 4.11 require inspection, measuring and equipment testing; likewise, IEC 17025: 2005 in section: 5.5.2 requires the equipment to be calibrated or verified before being put into use. In our laboratory, quality control is often accomplished by standards set done by the laboratory scientists themselves; however, at present, Hellma secondary calibration standards (4026 - Holmium oxide - Filters: F0, F2, F3, F4 and filter didymium - F7) have been used in order to verify if errors in the laboratory have been close to the 1-2% margin. Control graphs were made by using the results of synthetically prepared standards and standardized spectral calibration certificates. The set of secondary calibration standards permits to check the accuracy of the spectrophotometers used in research for both the absorbance in the visible spectrum (at 440, 465, 546, 590 and 635 nm wavelengths) and for the wavelengths (270, 280, 300, 320 nm) of the ultraviolet light. Filters (F0, F2, F3, F4 and F7) are stable and do not suffer the influence of temperature (the influence is negligible), the F0 filter was being used as a blank. The purpose is to verify whether the spectrometer needs adjustments, an important procedure to check absorbance stability, baseline flatness, slit width accuracy and stray radiation. The calibration tests are performed annually in our laboratory and recalibration of Hellma secondary standards is recommended every two years. The results show that the Chemical Dosimetry Laboratory in CRCN has a calibrated spectrophotometer and their synthetic standards for Fricke dosimetry could be used as an alternative method for testing the proficiency and competence of calibration laboratories in accordance with the regulations and standards. (author)

  2. Breach of clause of local content by the concessionaire: sanctions imposed by the ANP (Agencia Nacional do Petroleo, Gas Natural e Biocombustives); Descumprimento da clausula de conteudo local por parte do concessionario: sancoes impostas pela ANP (Agencia Nacional do Petroleo, Gas Natural e Biocombustiveis)

    Energy Technology Data Exchange (ETDEWEB)

    Nunes, Cintia Bezerra de Melo Pereira [Universidade Federal do Rio Grande do Norte (UFRN), Natal, RN (Brazil). Faculdade de Direito], email: cintianunes@gmail.com

    2009-08-15

    The hydrocarbon exploration in the country follows the dictates expressly provided in the Constitution: it is a monopoly of the Union, can carry out the activities of the sector be undertaken by state enterprises or private, domestic or foreign. They explore oil and natural gas within the boundaries of the blocks awarded to them by means of a concession contract signed with the Agencia Nacional do Petroleo, Natural Gas e Biocombustives (hereafter ANP) after the bidding procedure, which is also done through this federal agency. The activity is then performed by the companies under their own risk, automatically acquiring the ownership of the hydrocarbons produced in accordance with Article 26 of the Petroleum Law (Federal Law No. 9.478/1997). The tenders held by the ANP have three criteria for judging the deal: Signature Bonus (amount to be paid by the bidder to the Union), the Minimum Exploration Program (business plan) and Local Content (planned spending on goods and services of domestic industry ). After the evaluation of bids, the winning bidder is required to sign the concession contract, containing the contents of the proposal submitted. Thus, the failure of the proposal released by the winning bidder when the stage of the contract is not merely a breach of expectation, but true noncompliance with contract terms. Whereas this agreement is governed by public law, such an act of the concessionaire would incur serious consequences, which will be object of this work, focusing on the provision of local content.

  3. On the Cultivation of Students' Sense of the Love for the Alma Mater during Higher Education%培养学生爱校情怀在高等教育中的作用和途径

    Institute of Scientific and Technical Information of China (English)

    赵慧

    2011-01-01

    The survey from MyCOS shows that the graduates from colleges and universities are not willing to recommend their alma mater to the public at present.In order to increase the students' acceptability of their alma mater,colleges and universities should not only make a great effort to do a good job in other aspects,but also focus on the cultivation of students' sense of the love for the alma mater in the process of higher education.The thesis mainly indicates the cultivation of students' sense of the love for the alma mater from the following three points.%麦可思公司的调查结果显示,目前各类高校的毕业生对母校的推荐度普遍较低。要提高学生对学校的认可度,高校在努力做好其它各项工作的同时,应该把大学生爱校情怀的培养贯穿于高等教育的始终。可以通过抓住新生入学契机,加强培养学生爱校情怀,搭建学生爱校情怀的平台,注重学生的毕业教育等三条途径现实对大学生爱校情怀的培养。

  4. Nonaqueous magnetic nanoparticle suspensions with controlled particle size and nuclear magnetic resonance properties.

    Science.gov (United States)

    Meledandri, Carla J; Stolarczyk, Jacek K; Ghosh, Swapankumar; Brougham, Dermot F

    2008-12-16

    We report the preparation of monodisperse maghemite (gamma-Fe2O3) nanoparticle suspensions in heptane, by thermal decomposition of iron(III) acetylacetonate in the presence of oleic acid and oleylamine surfactants. By varying the surfactant/Fe precursor mole ratio during synthesis, control was exerted both over the nanocrystal core size, in the range from 3 to 6 nm, and over the magnetic properties of the resulting nanoparticle dispersions. We report field-cycling 1H NMR relaxation analysis of the superparamagnetic relaxation rate enhancement of nonaqueous suspensions for the first time. This approach permits measurement of the relaxivity and provides information on the saturation magnetization and magnetic anisotropy energy of the suspended particles. The saturation magnetization was found to be in the expected range for maghemite particles of this size. The anisotropy energy was found to increase significantly with decreasing particle size, which we attribute to increased shape anisotropy. This study can be used as a guide for the synthesis of maghemite nanoparticles with selected magnetic properties for a given application.

  5. A Phylogenetically Conserved Group of Nuclear Factor-Y Transcription Factors Interact to Control Nodulation in Legumes.

    Science.gov (United States)

    Baudin, Maël; Laloum, Tom; Lepage, Agnès; Rípodas, Carolina; Ariel, Federico; Frances, Lisa; Crespi, Martin; Gamas, Pascal; Blanco, Flavio Antonio; Zanetti, Maria Eugenia; de Carvalho-Niebel, Fernanda; Niebel, Andreas

    2015-12-01

    The endosymbiotic association between legumes and soil bacteria called rhizobia leads to the formation of a new root-derived organ called the nodule in which differentiated bacteria convert atmospheric nitrogen into a form that can be assimilated by the host plant. Successful root infection by rhizobia and nodule organogenesis require the activation of symbiotic genes that are controlled by a set of transcription factors (TFs). We recently identified Medicago truncatula nuclear factor-YA1 (MtNF-YA1) and MtNF-YA2 as two M. truncatula TFs playing a central role during key steps of the Sinorhizobium meliloti-M. truncatula symbiotic interaction. NF-YA TFs interact with NF-YB and NF-YC subunits to regulate target genes containing the CCAAT box consensus sequence. In this study, using a yeast two-hybrid screen approach, we identified the NF-YB and NF-YC subunits able to interact with MtNF-YA1 and MtNF-YA2. In yeast (Saccharomyces cerevisiae) and in planta, we further demonstrated by both coimmunoprecipitation and bimolecular fluorescence complementation that these NF-YA, -B, and -C subunits interact and form a stable NF-Y heterotrimeric complex. Reverse genetic and chromatin immunoprecipitation-PCR approaches revealed the importance of these newly identified NF-YB and NF-YC subunits for rhizobial symbiosis and binding to the promoter of MtERN1 (for Ethylene Responsive factor required for Nodulation), a direct target gene of MtNF-YA1 and MtNF-YA2. Finally, we verified that a similar trimer is formed in planta by the common bean (Phaseolus vulgaris) NF-Y subunits, revealing the existence of evolutionary conserved NF-Y protein complexes to control nodulation in leguminous plants. This sheds light on the process whereby an ancient heterotrimeric TF mainly controlling cell division in animals has acquired specialized functions in plants.

  6. 硬脊膜完整性可影响脑脊液中细胞因子的水平☆%Dura mater spinalis integrity may influence cytokine levels in the cerebrospinal fluid

    Institute of Scientific and Technical Information of China (English)

    白万山; 王新伟; 袁文; 王占超; 梁磊; 王会学

    2013-01-01

    BACKGROUND:Pathophysiological mechanisms after spinal cord injury are very complex, so there is no compressive and in-depth understanding on it. OBJECTIVE:To study the effect of dura mater spinalis integrity on cytokine levels in the cerebrospinal fluid of animal models of spinal cord injury. METHODS:The white rabbit models of spinal cord injury were established using clamp compression method, and then the models were randomly divided into four groups:no dura mater spinalis defect group, dura mater spinalis defect group, dura mater spinalis defect composite with membrane repairing group and dura mater spinalis defect composite with autologous fascia repair group. Enzyme-linked immunosorbent assay was performed to detect the changes of levels of cytokines (interleukin-6, interleukin-10 and tumor necrosis factorα) in the cerebrospinal fluid at 30 minutes, 1, 3, 6, 12 and 36 hours after surgery. RESULTS AND CONCLUSION:The levels of interleukin-6, interleukin-10 and tumor necrosis factorαin the cerebrospinal fluid of the dura mater spinalis defect group, dura mater spinalis defect composite with membrane repairing group and dura mater spinalis defect composite with autologous fascia repair group were significantly lower than those of the no dura mater spinalis defect group at 6 hours after surgery (P0.05). The results indicate that maintaining the integrity of dura mater spinalis of the spinal cord injury model can affect the levels of interleukin-6, interleukin-10 and tumor necrosis factorαin the cerebrospinal fluid, thus inhibiting the inflammatory response.%  背景:脊髓损伤后的病理生理机制非常复杂,人们对此认识还很不全面、深入。目的:观察脊髓损伤动物模型中硬脊膜完整性对脑脊液内细胞因子水平的影响。  方法:采用钳夹压迫法建立新西兰大白兔脊髓损伤模型,随机分为无硬脊膜缺损组、硬脊膜缺损组、硬脊膜缺损复合膜修复组、硬脊膜缺损

  7. A preliminary user-friendly, digital console for the control room parameters supervision in old-generation Nuclear Plants

    Energy Technology Data Exchange (ETDEWEB)

    Memmi, F.; Falconi, L.; Cappelli, M.; Palomba, M.; Santoro, E.; Bove, R.; Sepielli, M. [UTFISST, ENEA Casaccia, via Anguillarese 301, Rome (Italy)

    2012-07-01

    Improvements in the awareness of a system status is an essential requirement to achieve safety in every kind of plant. In particular, in the case of Nuclear Power Plants (NPPs), a progress is crucial to enhance the Human Machine Interface (HMI) in order to optimize monitoring and analyzing processes of NPP operational states. Firstly, as old-fashioned plants are concerned, an upgrading of the whole console instrumentation is desirable in order to replace an analog visualization with a full-digital system. In this work, we present a novel instrument able to interface the control console of a nuclear reactor, developed by using CompactRio, a National Instruments embedded architecture and its dedicated programming language. This real-time industrial controller composed by a real-time processor and FPGA modules has been programmed to visualize the parameters coming from the reactor, and to storage and reproduce significant conditions anytime. This choice has been made on the basis of the FPGA properties: high reliability, determinism, true parallelism and re-configurability, achieved by a simple programming method, based on LabVIEW real-time environment. The system architecture exploits the FPGA capabilities of implementing custom timing and triggering, hardware-based analysis and co-processing, and highest performance control algorithms. Data stored during the supervisory phase can be reproduced by loading data from a measurement file, re-enacting worthwhile operations or conditions. The system has been thought to be used in three different modes, namely Log File Mode, Supervisory Mode and Simulation Mode. The proposed system can be considered as a first step to develop a more complete Decision Support System (DSS): indeed this work is part of a wider project that includes the elaboration of intelligent agents and meta-theory approaches. A synoptic has been created to monitor every kind of action on the plant through an intuitive sight. Furthermore, another important

  8. Expansión de las capacidades de funcionamiento de las Agencias Turísticas para la competitividad en el mercado turístico y construir una visión de Turismo Humano

    Directory of Open Access Journals (Sweden)

    Félix Jiménez Jiménez

    2015-01-01

    Full Text Available El objetivo central es proponer la técnica metodológica denominada “expansión de las capacidades turísticas de funcionamiento” o “de mercado turístico de las agencias turísticas” y posibilitar la construcción de un nuevo paradigma al que se denomina turismo humano; lo cual es posible mediante la oportunidad que brinda el método científico a través de la lógica empírica analítica de estudiar la teoría y la metodología del desarrollo humano; concluyéndose que su perspectiva expresada en el estudio de las capacidades de funcionamiento o mercado es válida y oportuna para estudiar la realidad turística. Así se da respuesta al recurrente fracaso de las pequeñas y medianas empresas turísticas (PYMES sustentadas en el modelo tradicional de economía positiva, racional-funcionalista. En teoría y praxis, la expansión de las capacidades turísticas de funcionamiento debe convertirse en la técnica principal para que las agencias turísticas (PYMES puedan incursionar con éxito en el mercado turístico, generar rentabilidad, bienestar individual y colectivo.

  9. Nuclear Confidence

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    The Fukushima nuclear accident provides valuable lessons for China national nuclear Corp.as it continues to expand its operations AS Japan’s Fukushima nuclear crisis sparks a global debate over nuclear safety,China National Nuclear Corp. (CNNC),the country’s largest nuclear plant operator, comes under the spotlight.

  10. Software development for ACR-approved phantom-based nuclear medicine tomographic image quality control with cross-platform compatibility

    Science.gov (United States)

    Oh, Jungsu S.; Choi, Jae Min; Nam, Ki Pyo; Chae, Sun Young; Ryu, Jin-Sook; Moon, Dae Hyuk; Kim, Jae Seung

    2015-07-01

    Quality control and quality assurance (QC/QA) have been two of the most important issues in modern nuclear medicine (NM) imaging for both clinical practices and academic research. Whereas quantitative QC analysis software is common to modern positron emission tomography (PET) scanners, the QC of gamma cameras and/or single-photon-emission computed tomography (SPECT) scanners has not been sufficiently addressed. Although a thorough standard operating process (SOP) for mechanical and software maintenance may help the QC/QA of a gamma camera and SPECT-computed tomography (CT), no previous study has addressed a unified platform or process to decipher or analyze SPECT phantom images acquired from various scanners thus far. In addition, a few approaches have established cross-platform software to enable the technologists and physicists to assess the variety of SPECT scanners from different manufacturers. To resolve these issues, we have developed Interactive Data Language (IDL)-based in-house software for crossplatform (in terms of not only operating systems (OS) but also manufacturers) analyses of the QC data on an ACR SPECT phantom, which is essential for assessing and assuring the tomographical image quality of SPECT. We applied our devised software to our routine quarterly QC of ACR SPECT phantom images acquired from a number of platforms (OS/manufacturers). Based on our experience, we suggest that our devised software can offer a unified platform that allows images acquired from various types of scanners to be analyzed with great precision and accuracy.

  11. Cold nuclear fusion

    Directory of Open Access Journals (Sweden)

    Huang Zhenqiang Huang Yuxiang

    2013-10-01

    Full Text Available In normal temperature condition, the nuclear force constraint inertial guidance method, realize the combination of deuterium and tritium, helium and lithium... And with a magnetic moment of light nuclei controlled cold nuclear collide fusion, belongs to the nuclear energy research and development in the field of applied technology "cold nuclear collide fusion". According to the similarity of the nuclear force constraint inertial guidance system, the different velocity and energy of the ion beam mixing control, developed ion speed dc transformer, it is cold nuclear fusion collide, issue of motivation and the nuclear power plant start-up fusion and power transfer system of the important equipment, so the merger to apply for a patent

  12. Photonic Crystals: Two-Dimensional Programmable Manipulation of Magnetic Nanoparticles on-Chip (Adv. Mater. 15/2014)

    DEFF Research Database (Denmark)

    Sarella, Anandakumar; Torti, Andrea; Donolato, Marco

    2014-01-01

    P. Vavassori and co-workers demonstrate on page 2384 that field-controlled displacement of magnetic domain walls in ferromagnetic nano-ring structures allows for capture and 2-dimensional remote manipulation of fluidborne magnetic nanoparticles over a chip surface.......P. Vavassori and co-workers demonstrate on page 2384 that field-controlled displacement of magnetic domain walls in ferromagnetic nano-ring structures allows for capture and 2-dimensional remote manipulation of fluidborne magnetic nanoparticles over a chip surface....

  13. Application of portable nuclear gauge to the control of soil, asphalt and concrete compaction; A aplicacao dos medidores nucleares portateis no controle de compactacao de solos, asfalto e concreto

    Energy Technology Data Exchange (ETDEWEB)

    Castro, Bruno Almeida Cunha de [PATTROL, Pavimentos, Tracados e Obras Ltda. (Brazil)

    1999-07-01

    This paper presents an overview on the density and humidity determination methodology by using nuclear techniques, describing the different process phases and demonstrating their advantages compared to the traditional methods.

  14. Nuclear moments

    CERN Document Server

    Kopferman, H; Massey, H S W

    1958-01-01

    Nuclear Moments focuses on the processes, methodologies, reactions, and transformations of molecules and atoms, including magnetic resonance and nuclear moments. The book first offers information on nuclear moments in free atoms and molecules, including theoretical foundations of hyperfine structure, isotope shift, spectra of diatomic molecules, and vector model of molecules. The manuscript then takes a look at nuclear moments in liquids and crystals. Discussions focus on nuclear paramagnetic and magnetic resonance and nuclear quadrupole resonance. The text discusses nuclear moments and nucl

  15. 核磁共振中的量子控制∗%Quantum control of nuclear magnetic resonance spin systems

    Institute of Scientific and Technical Information of China (English)

    李俊; 崔江煜; 杨晓东; 罗智煌; 潘健; 余琦; 李兆凯; 彭新华; 杜江峰

    2015-01-01

    With the development of quantum information science, the active manipulation of quantum systems is becoming an important research frontier. To build realistic quantum information processors, one of the challenges is to implement arbitrary desired operations with high precision on quantum systems. A large number of quantum control methods and relevant numerical techniques have been put forward in recent years, such as quantum optimal control and quantum feedback control. Nuclear magnetic resonance (NMR) spin systems offer an excellent testbed to develop benchmark tools and techniques for controlling quantum systems. In this review paper, we briefly introduce some of the basic control ideas developed for NMR systems in recent years. We first explain, for the liquid spin systems, the physics of various couplings and the causes of relaxation effects. These mechanisms govern the system dynamics, and thus are crucial for constructing rigorous and efficient control models. We also identify three types of available control means: 1) raido-frequency fields as coherent controls; 2) phase cycling, gradient fields and relaxation effects as non-unitary controls; 3) radiation damping effect as feedback control mechanism. Then, we elucidate some important control tasks, which may arise from the conventional NMR spectroscopy (e.g., pulse design and polarization transfer) or from quantum information science (e.g., algorithmic cooling and pseudo-pure state preparation). In the last part, we review some of the most important control methods that are applicable to NMR control tasks. For systems with a relatively small number of spins, it is possible to use analytic optimal control theory to realize the target unitary operations. However, for larger systems, numerical methods are necessary. The gradient ascent pulse engineering algorithm and pulse compiler techniques are the most successful techniques for implementing complicated quantum networks currently. There are some interesting

  16. Organosilica: Chemistry of Mesoporous Organosilica in Nanotechnology: Molecularly Organic-Inorganic Hybridization into Frameworks (Adv. Mater. 17/2016).

    Science.gov (United States)

    Chen, Yu; Shi, Jianlin

    2016-05-01

    Organic-inorganic hybrid materials can combine the advantages of organic and inorganic materials, and overcome their drawbacks accordingly. On page 3235, Y. Chen and J. L. Shi review and discuss research progress on the design, synthesis, structure, and composition control of organic-inorganic hybrid mesoporous organosilica nanoparticles (MONs). Extensive applications of MONs in nanotechnology, mainly in nanomedicine, nanocatalysis and nanofabrication are discussed.

  17. Direct digital control of furnaces irradiated in nuclear reactors; Surveillance et regulation multiplexee par calculateur numerique de fours irradies

    Energy Technology Data Exchange (ETDEWEB)

    Joumard, R. [Commissariat a l' Energie Atomique, Grenoble (France). Centre d' Etudes Nucleaires

    1969-07-01

    An experimental direct digital control system has been realised in the 'C.E.N.G.', in order to verify that a computer makes easier the control of the experiments done in the nuclear reactors and to solve the theoretical and technical difficulties. The regulation is applied to thermal processes. The sampled data systems theory permits to choose the type of an efficient and simple digital compensator, and to establish a diagram which gives the values of the correcting parameters (obtained by minimizing the difference between the output and the input when perturbations occur). The programme execute, in simultaneity, supervision and regulation. Complex possibilities of printing out measures and alarms existed. The computer works out an incremental correction which makes step motors to turn. These motors act on the heating organs. The theoretical values and answers have been confirmed. The accuracy was limited essentially by the input quantification (1/1000 th). The comfort of such a system has been noticeable. (author) [French] Une installation de controle numerique direct fut realisee a titre experimental au C.E.N.G pour verifier qu'un ordinateur rendait plus aisee l'exploitation des experiences faites en pile nucleaire et pour degager les difficultes theoriques et techniques. La regulation s'applique a des processus thermiques. La theorie des systemes echantillonnes a permis de choisir un type de correcteur numerique simple et efficace et d'etablir un abaque qui donne les valeurs des parametres correcteurs minimisant les ecarts enregistres entre la reponse et la consigne en presence de perturbations. Le programme effectuait simultanement de la surveillance et de la regulation. Une restitution complexe des informations et des alarmes sur machine a ecrire etait possible. Le calculateur elaborait une correction incrementielle qui faisait tourner des moteurs pas a pas, lesquels commandaient les organes de puissance de chauffage. Les valeurs

  18. 秦山核电二期核岛控制系统维护优化及改进%The Maintenance Improvement Of Nuclear Island Control System in Qinshan Nuclear Power PlantⅡ

    Institute of Scientific and Technical Information of China (English)

    张洁

    2016-01-01

    秦山二期核岛控制系统采用的是Foxboro公司的SPEC200组装式仪表,主要采用小规模集成电路、运算放大器为机组的元件来控制。过程仪表机柜系统(KRG)参与核岛控制及保护信号处理过程,是核电厂核岛核辅重要的信号处理系统,其稳定运行是保障电厂安全运行的一道重要屏障。本文简要介绍了秦山核电二期扩建机组过程仪表系统的原理及功能,结合系统多年运行事件反馈和现场工作经验,从电源改造、电源机箱维护优化、组件维护优化、等几个方面,剖析了系统现存问题和故障现象,对后续系统维护提出了相应的优化改进建议。%Nuclear island control system in Qinshan nuclear power plant Ⅱ is designed based on the Foxboro’s SPEC 200 system,which is controlled by the components mainly including small-scale integrated circuits and operational amplifiers. Processing instrument system can also be called KRG system , it is a important signal processing system for nuclear island and nuclear auxiliary system and participate in nuclear island controlling and protect signal processing. Its safe operation is very important to the safety of the unit. This paper briefly describes the principle and function of KRG system . According to the feedback of operating experience and experience in the field, it deeply analyzes the existing problems of the system in multiple aspects including power supply improvement, component maintenance, digital transformation. It also proposes optimization suggestion for the system.

  19. Final Technical Report on Quantifying Dependability Attributes of Software Based Safety Critical Instrumentation and Control Systems in Nuclear Power Plants

    Energy Technology Data Exchange (ETDEWEB)

    Smidts, Carol [The Ohio State Univ., Columbus, OH (United States); Huang, Funqun [The Ohio State Univ., Columbus, OH (United States); Li, Boyuan [The Ohio State Univ., Columbus, OH (United States); Li, Xiang [The Ohio State Univ., Columbus, OH (United States)

    2016-03-25

    With the current transition from analog to digital instrumentation and control systems in nuclear power plants, the number and variety of software-based systems have significantly increased. The sophisticated nature and increasing complexity of software raises trust in these systems as a significant challenge. The trust placed in a software system is typically termed software dependability. Software dependability analysis faces uncommon challenges since software systems’ characteristics differ from those of hardware systems. The lack of systematic science-based methods for quantifying the dependability attributes in software-based instrumentation as well as control systems in safety critical applications has proved itself to be a significant inhibitor to the expanded use of modern digital technology in the nuclear industry. Dependability refers to the ability of a system to deliver a service that can be trusted. Dependability is commonly considered as a general concept that encompasses different attributes, e.g., reliability, safety, security, availability and maintainability. Dependability research has progressed significantly over the last few decades. For example, various assessment models and/or design approaches have been proposed for software reliability, software availability and software maintainability. Advances have also been made to integrate multiple dependability attributes, e.g., integrating security with other dependability attributes, measuring availability and maintainability, modeling reliability and availability, quantifying reliability and security, exploring the dependencies between security and safety and developing integrated analysis models. However, there is still a lack of understanding of the dependencies between various dependability attributes as a whole and of how such dependencies are formed. To address the need for quantification and give a more objective basis to the review process -- therefore reducing regulatory uncertainty

  20. International law and arms control: Soviet Union and Russia’s stance on nuclear test ban treaties

    Directory of Open Access Journals (Sweden)

    Renata Hessmann Dalaqua

    2013-12-01

    Full Text Available The long-lasting struggle against nuclear tests can be examined through different perspectives. In this paper, the focus will be on the part played by the USSR and Russia in the international efforts aimed at establishing legal instruments to outlaw nuclear explosions in space, underground, under water and in the atmosphere.  A luta contra os testes nucleares pode ser examinada sob diferentes perspectivas. Aqui, o foco recairá sobre o papel desempenhado pela União Soviética e Rússia na criação de instrumentos legais para proibir explosões nucleares no espaço, no subsolo, debaixo da água e na atmosfera.

  1. Final Technical Report on Quantifying Dependability Attributes of Software Based Safety Critical Instrumentation and Control Systems in Nuclear Power Plants

    Energy Technology Data Exchange (ETDEWEB)

    Smidts, Carol [The Ohio State Univ., Columbus, OH (United States); Huang, Funqun [The Ohio State Univ., Columbus, OH (United States); Li, Boyuan [The Ohio State Univ., Columbus, OH (United States); Li, Xiang [The Ohio State Univ., Columbus, OH (United States)

    2016-03-25

    With the current transition from analog to digital instrumentation and control systems in nuclear power plants, the number and variety of software-based systems have significantly increased. The sophisticated nature and increasing complexity of software raises trust in these systems as a significant challenge. The trust placed in a software system is typically termed software dependability. Software dependability analysis faces uncommon challenges since software systems’ characteristics differ from those of hardware systems. The lack of systematic science-based methods for quantifying the dependability attributes in software-based instrumentation as well as control systems in safety critical applications has proved itself to be a significant inhibitor to the expanded use of modern digital technology in the nuclear industry. Dependability refers to the ability of a system to deliver a service that can be trusted. Dependability is commonly considered as a general concept that encompasses different attributes, e.g., reliability, safety, security, availability and maintainability. Dependability research has progressed significantly over the last few decades. For example, various assessment models and/or design approaches have been proposed for software reliability, software availability and software maintainability. Advances have also been made to integrate multiple dependability attributes, e.g., integrating security with other dependability attributes, measuring availability and maintainability, modeling reliability and availability, quantifying reliability and security, exploring the dependencies between security and safety and developing integrated analysis models. However, there is still a lack of understanding of the dependencies between various dependability attributes as a whole and of how such dependencies are formed. To address the need for quantification and give a more objective basis to the review process -- therefore reducing regulatory uncertainty

  2. Development of advanced direct perception displays for nuclear power plants to enhance monitoring, control and fault management

    Energy Technology Data Exchange (ETDEWEB)

    Jones, B.G.; Shaheen, S.; Moray, N. [and others

    1997-08-01

    Traditional Single-Sensor-Single Indicator (SSSI) displays are poorly matched to the cognitive abilities of operators, especially for large and complex systems. It is difficult for operators to monitor very large arrays of displays and controls, and to integrate the information displayed therein. In addition, standard operating procedures (SOPs) are bulky (running to many hundreds of pages) and difficult to use, and operators may become lost. For these reasons, and also because it is becoming increasingly difficult to find replacements for aging hardware components, there is a trend towards computerized graphical interfaces for nuclear power plants (NPPs). There is, however, little rational theory for display design in this domain. This report describes some recent theoretical developments and shows how to develop displays which will greatly reduce the cognitive load on the operator and allow the use of perceptual rather than cognitive mechanisms while using SON and to support state diagnosis and fault management. The report outlines the conceptual framework within which such a new approach could be developed, and provides an example of how the operating procedures for the start-up sequence of a NPP could be realized. A detailed description of a set of displays for a graphical interface for the SON of the feedwater system is provided as an example of how the proposed approach could be realized, and a general account of how it would fit into the overall start-up sequence is given. Examples of {open_quotes}direct perception{close_quotes} or {open_quotes}ecological{close_quotes} configural state space displays to support the use of the proposed direct manipulation SOP interface are provided, and also a critical discussion which identifies some difficulties which may be anticipated should the general approach herein advocated be adopted.

  3. Revision curricular a partir de un analisis comparativo de las discrepancias en los curriculos de una escuela de optometria en Puerto Rico con las competencias requeridas para las agencias de revalida y acreditacion 2004

    Science.gov (United States)

    Rivera Pacheco, Andres

    El proposito de esta investigacion, un estudio cualitativo de caso, fue comparar y contrastar el curriculo vigente de la Escuela de Optometria de la UIAPR con las competencias y estandares requeridos por las agencias de acreditacion y de revalida. Con este proposito, decidimos realizar una revision y un analisis de documentos: el prontuario de cada uno de los cursos de los curriculos implantados en el 1993 y en el 2001; las competencias y estandares establecidos por las agencias de revalida y de acreditacion; y las estadisticas en las que se analiza el porcentaje de estudiantes que aprueban cada una de las partes de los examenes de revalida entre el 1998 al 2003. Se realizaron entrevistas dirigidas para dar apoyo y complementar la revision y el analisis de estos documentos. Los participantes de las entrevistas fueron tres estudiantes de la clase de optometria del 2004 (ultima clase del curriculo del 1993); tres estudiantes de la clase de optometria del 2005 (primera clase graduanda del curriculo vigente) y tres profesores y/o directores de los Departamentos de Ciencias Basicas, Ciencias Clinicas y Cuidado al Paciente. Esta investigacion se enmarco en el modelo de evaluacion curricular de discrepancia de Malcolm Provus y en el modelo de desarrollo basado en competencias. Uno de los hallazgos mas importantes del estudio es que los cambios que se implantaron al curriculo del 2001 no han logrado que los estudiantes mejoren su ejecucion en los examenes de revalida. Por otro lado, se encontro que el curriculo vigente atiende completamente los estandares de la practica de Optometria, pero no las competencias. Esta informacion fue validada mediante el uso de una tabla de cotejo para el analisis de los cursos y de la informacion obtenida de las entrevistas. El estudio determina y concluye que existen discrepancias entre los prontuarios de los cursos del curriculo y las competencias requeridas por la agencia de revalida. Segundo, que el Departamento de Ciencias Basicas es el

  4. Effects of variation of chitosan concentration on the characteristics of membrane cellulose bacteria-chitosan biocomposites as candidates for artificial dura mater

    Science.gov (United States)

    Widiyanti, Prihartini; Jabbar, Hajria; Rudyardjo, Djony Izak

    2017-02-01

    This study was conducted to determine the effect of variation in concentration of chitosan on the physical and biological characteristics of the membrane of bacterial cellulose-chitosan biocomposites through immersion precipitation method. Bacterial cellulose membrane was soaked in a solution of chitosan whose concentration variation are 0.1%; 0.3%; 0.5% and 0.7%. The characterization tests which were conducted included the analysis of functional groups (FTIR), tensile strength test, morphology test (SEM), and cytotoxicity assay using MTT Assay method. Based on the cluster analysis test, the results of FTIR spectra indicate changes in the physical bond which means that there is interaction between the bacterial cellulose membrane with chitosan on each sample. The bacteria produced cellulose membrane with tensile strength of 10.53 ± 0.19 MPa while the microbial cellulose membrane by adding 0.5% chitosan concentration had tensile strength value of 8:58 ± 0.19 MPa. It shows that with the addition of chitosan it would decrease the tensile strength in microbial cellulose membrane. This was shown by 496.2 nm - 2,032 µm pore size with a thickness (mm) of 0:35 ± 0.33 to 0.81 ± 0.26. Based on the test results of the analysis of functional groups, tensile strength test, and morphology test, membrane microbial cellulose-chitosan biocomposites have the potential to be used as artificial dura mater candidate.

  5. Automatic chemical monitoring in the composition of functions performed by the unit level control system in the new projects of nuclear power plant units

    Science.gov (United States)

    Denisova, L. G.; Khrennikov, N. N.

    2014-08-01

    The article presents information on the state of regulatory framework and development of a subsystem for automated chemical monitoring of water chemistries in the primary and secondary coolant circuits used as part of the automatic process control system in new projects of VVER reactor-based nuclear power plant units. For the strategy of developing and putting in use the water chemistry-related part of the automated process control system within the standard AES-2006 nuclear power plant project to be implemented, it is necessary to develop regulatory documents dealing with certain requirements imposed on automatic water chemistry monitoring systems in accordance with the requirements of federal codes and regulations in the field of using atomic energy.

  6. Nuclear ventriculography

    Science.gov (United States)

    ... ventriculography (RNV); Multiple gate acquisition scan (MUGA); Nuclear cardiology; Cardiomyopathy - nuclear ventriculography ... 56. Udelson JE, Dilsizian V, Bonow RO. Nuclear cardiology. In: Bonow RO, Mann DL, Zipes DP, Libby ...

  7. Nuclear Medicine.

    Science.gov (United States)

    Badawi, Ramsey D.

    2001-01-01

    Describes the use of nuclear medicine techniques in diagnosis and therapy. Describes instrumentation in diagnostic nuclear medicine and predicts future trends in nuclear medicine imaging technology. (Author/MM)

  8. Expansión de las capacidades de funcionamiento de las Agencias Turísticas para la competitividad en el mercado turístico y construir una visión de Turismo Humano

    OpenAIRE

    Félix Jiménez Jiménez; Ana Isabel Muñoz Mason; Laura Fuentes Moraleda

    2015-01-01

    El objetivo central es proponer la técnica metodológica denominada “expansión de las capacidades turísticas de funcionamiento” o “de mercado turístico de las agencias turísticas” y posibilitar la construcción de un nuevo paradigma al que se denomina turismo humano; lo cual es posible mediante la oportunidad que brinda el método científico a través de la lógica empírica analítica de estudiar la teoría y la metodología del desarrollo humano; concluyéndose que su perspectiva expresada en el estu...

  9. Nuclear Forensics at Los Alamos National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Kinman, William Scott [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Steiner, Robert Ernest [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Lamont, Stephen Philip [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-09-30

    Nuclear forensics assists in responding to any event where nuclear material is found outside of regulatory control; a response plan is presented and a nuclear forensics program is undergoing further development so that smugglers are sufficiently deterred.

  10. Inspection of nuclear pressure equipment: principles, issues and perspectives; Le controle des equipements sous pression nucleaires: principes, enjeux et perspectives

    Energy Technology Data Exchange (ETDEWEB)

    Limousin, S. [Autorite de Surete Nucleaire (ASN), Dir. des Equipements sous Pression Nucleaires, 75 - Paris (France)

    2010-02-15

    French regulations about nuclear pressure equipment (like steam generators and the reactor pressure vessel) take into account hazards due to the energy contained in the equipment but also add specific requirements due for instance to the radioactivity or safety for instance. ASN is in charge of the conformity assessment of the most important equipment and monitors the licensee who is responsible of in service inspection and maintenance. Because of the internationalization of nuclear component manufacturing, and consequently new comers in this area, a careful monitoring of subcontractors is needed. The major anomalies detected in steam generator over the past few years showed the necessity of being careful and humble towards degradation mechanisms. Nuclear pressure equipment regulations enables ASN to perform an efficient oversight of licensees and component manufacturer in a context of international manufacturing and licence renewal. (author)

  11. Nuclear Theory - Nuclear Power

    Science.gov (United States)

    Svenne, J. P.; Canton, L.; Kozier, K. S.

    2008-01-01

    The results from modern nuclear theory are accurate and reliable enough to be used for practical applications, in particular for scattering that involves few-nucleon systems of importance to nuclear power. Using well-established nucleon-nucleon (NN) interactions that fit well the NN scattering data, and the AGS form of the three-body theory, we have performed precise calculations of low-energy neutron-deuteron (n+d) scattering. We show that three-nucleon force effects that have impact on the low-energy vector analyzing powers have no practical effects on the angular distribution of the n+d cross-section. There appear to be problems for this scattering in the evaluated nuclear data file (ENDF) libraries, at the incident neutron energies less than 3.2 MeV. Supporting experimental data in this energy region are rather old (>25 years), sparse and often inconsistent. Our three-body results at low energies, 50 keV to 10.0 MeV, are compared to the ENDF/B-VII.0 and JENDL (Japanese Evaluated Nuclear Data Library) -3.3 evaluated angular distributions. The impact of these results on the calculated reactivity for various critical systems involving heavy water is shown.

  12. The rejection of the comprehensive nuclear test ban treaty by the US Senate: a reverse for the nuclear arms control?; Le rejet du traite d'interdiction complete des essais nucleaires par le Senat Americain: un revers pour l'arms control nucleaire?

    Energy Technology Data Exchange (ETDEWEB)

    Sitt, B. [Universite de Marne la Vallee, 77 (France)

    2000-07-01

    On October 13, 1999, after a hasty debate, the US Senate rejected the comprehensive nuclear test ban treaty (CTBT) signed 3 years ago. This article analyses this event with respect to the US domestic context (discussions at the Senate, reaction of the Presidency) and with respect to the international context (international reactions, future of the treaty, consequences on arms control policy). (J.S.)

  13. Efeito da quercetina sobre o extravasamento plasmático no sistema nervoso dura-mater de ratos

    Directory of Open Access Journals (Sweden)

    Luiz Arthur Rangel Cyrino

    2002-01-01

    Full Text Available Estudos recentes têm demonstrado que os bioflavonóides afetam vários sistemas enzimáticos nos mamíferos. A dura-máter é um tecido que recebe inervação peptidérgica. No cérebro, a inflamação neurogênica envolve a liberação da substância P (SP por terminais nervosos sensoriais e é modulada pela endopeptidase neutra (NEP e pela enzima conversora da angiotensina (ECA. Neste estudo, avaliamos o efeito da quercetina, que representa mais de 50% dos bioflavonóides, sobre o extravasamento plasmático induzido pela SP em tecidos selecionados no sistema nervoso central de ratos e dura-máter. Também examinamos o efeito da inibição seletiva das enzimas metabolizadoras da SP (NEP e ECA. A administração de SP (10 nmol/kg e 30 nmol/kg, i.v. aumentou o extravasamento plasmático de maneira dose dependente na duramáter, não apresentando nenhum efeito nos outros tecidos; este efeito foi potencializado por inibidores seletivos da NEP e da ECA. A quercetina (30 mg/kg v.o. aumentou o extravasamento plasmático em relação ao controle em todos os tecidos. O prétratamento com quercetina potenciou significativamente o extravasamento plasmático induzido pela SP (10 nmol/kg na dura-máter. Resultados obtidos com o pré-tratamento com antagonistas específicos para receptores da substância P e bradicinina (NK-1 e B2 sugerem que o aumento do extravasamento plasmático induzido pela quercetina e a potenciação da resposta à SP foram devidos ao acúmulo deste neuropeptídeo na dura-máter.

  14. A nuclear criticality safety assessment of the loss of moderation control in 2 1/2 and 10-ton cylinders containing enriched UF{sub 6}

    Energy Technology Data Exchange (ETDEWEB)

    Newvahner, R.L. [Martin Marietta Energy Systems, Inc., Piketon, OH (United States); Pryor, W.A. [PAI Corp., Oak Ridge, TN (United States)

    1991-12-31

    Moderation control for maintaining nuclear criticality safety in 2 {1/2}-ton, 10-ton, and 14-ton cylinders containing enriched uranium hexafluoride (UF{sub 6}) has been used safely within the nuclear industry for over thirty years, and is dependent on cylinder integrity and containment. This assessment evaluates the loss of moderation control by the breaching of containment and entry of water into the cylinders. The first objective of this study was to estimate the required amounts of water entering these large UF{sub 6} cylinders to react with, and to moderate the uranium compounds sufficiently to cause criticality. Hypothetical accident situations were modeled as a uranyl fluoride (UO{sub 2}F{sub 2}) slab above a UF{sub 6} hemicylinder, and a UO{sub 2}F{sub 2} sphere centered within a UF{sub 6} hemicylinder. These situations were investigated by computational analyses utilizing the KENO V.a Monte Carlo Computer Code. The results were used to estimate both the masses of water required for criticality, and the limiting masses of water that could be considered safe. The second objective of the assessment was to calculate the time available for emergency control actions before a criticality would occur, i.e., a {open_quotes}safetime{close_quotes}, for various sources of water and different size openings in a breached cylinder. In the situations considered, except the case for a fire hose, the safetime appears adequate for emergency control actions. The assessment shows that current practices for handling moderation controlled cylinders of low enriched UF{sub 6}, along with the continuation of established personnel training programs, ensure nuclear criticality safety for routine and emergency operations.

  15. Contribution to the safety assessment of instrumentation and control software for nuclear power plants: Application to SPIN N4

    Energy Technology Data Exchange (ETDEWEB)

    Soubies, B.; Henry, J.Y.; Le Meur, M. [and others

    1995-04-01

    1300 MWe pressurised water reactors (PWRs), like the 1400 MWe reactors, operate with microprocessor-based safety systems. This is particularly the case for the Digital Integrated Protection System (SPIN), which trips the reactor in an emergency and sets in action the safeguard functions. The softwares used in these systems must therefore be highly dependable in the execution of their functions. In the case of SPIN, three players are working at different levels to achieve this goal: the protection system manufacturer, Merlin Gerin; the designer of the nuclear steam supply system, Framatome; the operator of the nuclear power plants, Electricite de France (EDF), which is also responsible for the safety of its installations. Regulatory licenses are issued by the French safety authority, the Nuclear Installations Safety Directorate (French abbreviation DSIN), subsequent to a successful examination of the technical provisions adopted by the operator. This examination is carried out by the IPSN and the standing group on nuclear reactors. This communication sets out: the methods used by the manufacturer to develop SPIN software for the 1400 MWe PWRs (N4 series); the approach adopted by the IPSN to evaluate the safety software of the protection system for the N4 series of reactors.

  16. A Dual Mechanism Controls Nuclear Localization in the Atypical Basic-Helix-Loop-Helix Protein PAR1 of Arabidopsis thaliana

    Institute of Scientific and Technical Information of China (English)

    Anahit Galstyan; Jordi Bou-Torrent; Irma Roig-Villanova; Jaime F. Martínez-García

    2012-01-01

    PAR1 is an atypical basic-helix-loop-helix (bHLH) protein that negatively regulates the shade avoidance syndrome in Arabidopsis thaliana acting as a transcriptional cofactor.Consistently with this function,PAR1 has to be in the nucleus to display biological activity.Previous structure-function analyses revealed that the N-terminal region of PAR1 drives the protein to the nucleus.However,truncated forms of PAR1 lacking this region still display biological activity,implying that PAR1 has additional mechanisms to localize into the nucleus.In this work,we compared the primary structure of PAR1 and various related and unrelated plant bHLH proteins,which led us to suggest that PAR1 contains a non-canonical nuclear localization signal (NLS) in the N-terminal region.By overexpressing truncated and mutated derivatives of PAR1,we have also investigated the importance of other regions of PAR1,such as the acidic and the extended HLH dimerization domains,for its nuclear localization.We found that,in the absence of the N-terminal region,a functional HLH domain is required for nuclear localization.Our results suggest the existence of a dual mechanism for PAR1 nuclear localization:(1) one mediated by the N-terminal non-consensus NLS and (2) a second one that involves interaction with other proteins via the dimerization domain.

  17. Material control in nuclear fuel fabrication facilities. Part I. Fuel descriptions and fabrication processes, P. O. 1236909 Final report

    Energy Technology Data Exchange (ETDEWEB)

    Borgonovi, G.M.; McCartin, T.J.; Miller, C.L.

    1978-12-01

    The report presents information on foreign nuclear fuel fabrication facilities. Fuel descriptions and fuel fabrication information for three basic reactor types are presented: The information presented for LWRs assumes that Pu--U Mixed Oxide Fuel (MOX) will be used as fuel.

  18. Preventing the spread of nuclear weapons : The law of arms control and the international non-proliferation regime

    NARCIS (Netherlands)

    Coppen, T.

    2016-01-01

    The proliferation of nuclear weapons remains a severe threat to international peace, security and stability. In order to counter this threat, the international community has taken numerous measures, legal and otherwise, resulting in a global framework of treaties and political agreements known as th

  19. Microarray analysis of gene expression after electrical stimulation of the dura mater surrounding the superior sagittal sinus in conscious adult rats

    Institute of Scientific and Technical Information of China (English)

    Jiang Lei; Dong Zhao; Li Fengpeng; Liu Ruozhuo; Qiu Enchao; Wang Xiaolin; Yu Shengyuan

    2014-01-01

    Background The molecular and cellular origins of migraine headache are among the most complex problems in contemporary neurology.Up to now the pathogenesis of migraine still remains unclearly defined.The objective of this study was to explore new factors that may be related to the mechanism of migraine.Methods The present study performed a comprehensive analysis of gene expression in the trigeminal nucleus caudalis induced by electrical stimulation of dura mater surrounding the superior sagittal sinus in conscious rats using microarray analysis followed by quantitative real-time reverse-transcribed polymerase chain reaction (qRT-PCR) verification.Student's two sample t-test was employed when two groups were compared.A P value <0.05 was considered to be statistically significant.Results Comparing the placebo and the electrical stimulation groups,40 genes were determined to be significantly differentially expressed.These significantly differentially expressed genes were involved in many pathways,including transporter activity,tryptophan metabolism,G protein signaling,kinase activity,actin binding,signal transducer activity,anion transport,protein folding,enzyme inhibitor activity,coenzyme metabolism,binding,ion transport,cell adhesion,metal ion transport,oxidoreductase activity,mitochondrion function,and others.Most of the genes were involved in more than 2 pathways.Of particular interest is the up-regulation of Phactr3 and Akap5 and the down-regulation of Kdr.Conclusion These findings may provide important clues for a better understanding of the molecular mechanism of migraine.

  20. NUCLEAR REACTOR

    Science.gov (United States)

    Miller, H.I.; Smith, R.C.

    1958-01-21

    This patent relates to nuclear reactors of the type which use a liquid fuel, such as a solution of uranyl sulfate in ordinary water which acts as the moderator. The reactor is comprised of a spherical vessel having a diameter of about 12 inches substantially surrounded by a reflector of beryllium oxide. Conventionnl control rods and safety rods are operated in slots in the reflector outside the vessel to control the operation of the reactor. An additional means for increasing the safety factor of the reactor by raising the ratio of delayed neutrons to prompt neutrons, is provided and consists of a soluble sulfate salt of beryllium dissolved in the liquid fuel in the proper proportion to obtain the result desired.