Holographical description of BPS Wilson loops in flavored ABJM theory
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Chen, Bin [Department of Physics, and State Key Laboratory of Nuclear Physics and Technology,Peking University, 5 Yiheyuan Rd, Beijing 100871 (China); Collaborative Innovation Center of Quantum Matter,5 Yiheyuan Rd, Beijing 100871 (China); Center for High Energy Physics, Peking University,5 Yiheyuan Rd, Beijing 100871 (China); Wu, Jun-Bao [Institute of High Energy Physics, and Theoretical Physics Center for Science Facilities,Chinese Academy of Sciences, 19B Yuquan Road, Beijing 100049 (China); Zhu, Meng-Qi [SISSA,Via Bonomea 265, I 34136, Trieste (Italy)
2014-12-22
As holographic description of BPS Wilson loops in N=3 flavored ABJM theory with N{sub f}=k=1, BPS M2-branes in AdS{sub 4}×N(1,1) are studied in details. Two 1/3-BPS membrane configurations are found. One of them is dual to the 1/3-BPS Wilson loop of Gaiotto-Yin type. The regulated membrane action captures precisely the leading exponential behavior of the vacuum expectation values of 1/3-BPS Wilson loops in the strong coupling limit, which was computed before using supersymmetric localization technique. Moreover, there is no BPS membrane with more supersymmetries in the background, under quite natural assumption on the membrane worldvolume. This suggests that there is no Wilson loop preserving more than 1/3 supersymmetries in such flavored ABJM theory.
Twistor Parametrization of Locally BPS Super-Wilson Loops
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Cristian Vergu
2017-01-01
Full Text Available We consider the kinematics of the locally BPS super-Wilson loop in N=4 super-Yang-Mills with scalar coupling from a twistorial point of view. We find that the kinematics can be described either as supersymmetrized pure spinors or as a point in the product of two super-Grassmannian manifolds G2∣2(4∣4×G2∣2(4∣4. In this description of the kinematics the scalar–scalar correlation function appearing in the one-loop evaluation of the super-Wilson loop can be neatly written as a sum of four superdeterminants.
Novel BPS Wilson loops in three-dimensional quiver Chern–Simons-matter theories
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Hao Ouyang
2016-02-01
Full Text Available We show that generic three-dimensional N=2 quiver super Chern–Simons-matter theories admit Bogomol'nyi–Prasad–Sommerfield (BPS Drukker–Trancanelli (DT type Wilson loops. We investigate both Wilson loops along timelike infinite straight lines in Minkowski spacetime and circular Wilson loops in Euclidean space. In Aharnoy–Bergman–Jafferis–Maldacena theory, we find that generic BPS DT type Wilson loops preserve the same number of supersymmetries as Gaiotto–Yin type Wilson loops. There are several free parameters for generic BPS DT type Wilson loops in the construction, and supersymmetry enhancement for Wilson loops happens for special values of the parameters.
Gravity duals of half-BPS Wilson loops
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D'Hoker, Eric; Estes, John; Gutperle, Michael
2007-01-01
We explicitly construct the fully back-reacted half-BPS solutions in Type IIB supergravity which are dual to Wilson loops with 16 supersymmetries in N = 4 super Yang-Mills. In a first part, we use the methods of a companion paper to derive the exact general solution of the half-BPS equations on the space AdS 2 x S 2 x S 4 x Σ, with isometry group SO(2, 1) x SO(3) x SO(5) in terms of two locally harmonic functions on a Riemann surface Σ with boundary. These solutions, generally, have varying dilaton and axion, and non-vanishing 3-form fluxes. In a second part, we impose regularity and topology conditions. These non-singular solutions may be parametrized by a genus g ≥ 0 hyperelliptic surface Σ, all of whose branch points lie on the real line. Each genus g solution has only a single asymptotic AdS 5 x S 5 region, but exhibits g homology 3-spheres, and an extra g homology 5-spheres, carrying respectively RR 3-form and RR 5-form charges. For genus 0, we recover AdS 5 x S 5 with 3 free parameters, while for genus g ≥ 1, the solution has 2g+5 free parameters. The genus 1 case is studied in detail. Numerical analysis is used to show that the solutions are regular throughout the g = 1 parameter space. Collapse of a branch cut on Σ subtending either a homology 3-sphere or a homology 5-sphere is non-singular and yields the genus g-1 solution. This behavior is precisely expected of a proper dual to a Wilson loop in gauge theory
Gravity duals of half-BPS Wilson loops
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D' Hoker, Eric; Estes, John; Gutperle, Michael [Department of Physics and Astronomy, University of California, Los Angeles, CA 90095 (United States)
2007-06-15
We explicitly construct the fully back-reacted half-BPS solutions in Type IIB supergravity which are dual to Wilson loops with 16 supersymmetries in N = 4 super Yang-Mills. In a first part, we use the methods of a companion paper to derive the exact general solution of the half-BPS equations on the space AdS{sub 2} x S{sup 2} x S{sup 4} x {sigma}, with isometry group SO(2, 1) x SO(3) x SO(5) in terms of two locally harmonic functions on a Riemann surface {sigma} with boundary. These solutions, generally, have varying dilaton and axion, and non-vanishing 3-form fluxes. In a second part, we impose regularity and topology conditions. These non-singular solutions may be parametrized by a genus g {>=} 0 hyperelliptic surface {sigma}, all of whose branch points lie on the real line. Each genus g solution has only a single asymptotic AdS{sub 5} x S{sup 5} region, but exhibits g homology 3-spheres, and an extra g homology 5-spheres, carrying respectively RR 3-form and RR 5-form charges. For genus 0, we recover AdS{sub 5} x S{sup 5} with 3 free parameters, while for genus g {>=} 1, the solution has 2g+5 free parameters. The genus 1 case is studied in detail. Numerical analysis is used to show that the solutions are regular throughout the g = 1 parameter space. Collapse of a branch cut on {sigma} subtending either a homology 3-sphere or a homology 5-sphere is non-singular and yields the genus g-1 solution. This behavior is precisely expected of a proper dual to a Wilson loop in gauge theory.
BPS Wilson loops and Bremsstrahlung function in ABJ(M): a two loop analysis
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Bianchi, Marco S. [Institut für Physik, Humboldt-Universität zu Berlin,Newtonstraße 15, 12489 Berlin (Germany); Griguolo, Luca [Dipartimento di Fisica e Scienze della Terra, Università di Parmaand INFN Gruppo Collegato di Parma,Viale G.P. Usberti 7/A, 43100 Parma (Italy); Leoni, Matias [Physics Department, FCEyN-UBA & IFIBA-CONICETCiudad Universitaria, Pabellón I, 1428, Buenos Aires (Argentina); Penati, Silvia [Dipartimento di Fisica, Università di Milano-Bicoccaand INFN, Sezione di Milano-Bicocca,Piazza della Scienza 3, I-20126 Milano (Italy); Seminara, Domenico [Dipartimento di Fisica, Università di Firenzeand INFN Sezione di Firenze,via G. Sansone 1, 50019 Sesto Fiorentino (Italy)
2014-06-19
We study a family of circular BPS Wilson loops in N=6 super Chern-Simons-matter theories, generalizing the usual 1/2-BPS circle. The scalar and fermionic couplings depend on two deformation parameters and these operators can be considered as the ABJ(M) counterpart of the DGRT latitudes defined in N=4 SYM. We perform a complete two-loop analysis of their vacuum expectation value, discuss the appearance of framing-like phases and propose a general relation with cohomologically equivalent bosonic operators. We make an all-loop proposal for computing the Bremsstrahlung function associated to the 1/2-BPS cusp in terms of these generalized Wilson loops. When applied to our two-loop result it reproduces the known expression. Finally, we comment on the generalization of this proposal to the bosonic 1/6-BPS case.
Structure constants of defect changing operators on the 1/2 BPS Wilson loop
Kim, Minkyoo; Kiryu, Naoki; Komatsu, Shota; Nishimura, Takuya
2017-12-01
We study three-point functions of operators on the 1/2 BPS Wilson loop in planar N = 4 super Yang-Mills theory. The operators we consider are "defect changing operators", which change the scalar coupled to the Wilson loop. We first perform the computation at two loops in general set-ups, and then study a special scaling limit called the ladders limit, in which the spectrum is known to be described by a quantum mechanics with the SL(2,R) symmetry. In this limit, we resum the Feynman diagrams using the Schwinger-Dyson equation and determine the structure constants at all order in the rescaled coupling constant. Besides providing an interesting solvable example of defect conformal field theories, our result gives invaluable data for the integrability-based approach to the structure constants.
Half-BPS Wilson loop and AdS2/CFT1
Giombi, Simone; Roiban, Radu; Tseytlin, Arkady A.
2017-09-01
We study correlation functions of local operator insertions on the 1/2-BPS Wilson line in N = 4 super Yang-Mills theory. These correlation functions are constrained by the 1d superconformal symmetry preserved by the 1/2-BPS Wilson line and define a defect CFT1 living on the line. At strong coupling, a set of elementary operator insertions with protected scaling dimensions correspond to fluctuations of the dual fundamental string in AdS5×S5 ending on the line at the boundary and can be thought of as light fields propagating on the AdS2 worldsheet. We use AdS/CFT techniques to compute the tree-level AdS2 Witten diagrams describing the strong coupling limit of the four-point functions of the dual operator insertions. Using the OPE, we also extract the leading strong coupling corrections to the anomalous dimensions of the "two-particle" operators built out of elementary excitations. In the case of the circular Wilson loop, we match our results for the 4-point functions of a special type of scalar insertions to the prediction of localization to 2d Yang-Mills theory.
Precision calculation of 1/4-BPS Wilson loops in AdS{sub 5}×S{sup 5}
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Forini, V. [Institut für Physik, Humboldt-Universität zu Berlin, IRIS Adlershof, Zum Großen Windkanal 6, 12489 Berlin (Germany); Puletti, V. Giangreco M. [Science Institute, University of Iceland,Dunhaga 3, 107 Reykjavik (Iceland); Griguolo, L. [Dipartimento di Fisica e Scienze della Terra, Università di Parma andINFN Gruppo Collegato di Parma,Viale G.P. Usberti 7/A, 43100 Parma (Italy); Seminara, D. [Dipartimento di Fisica, Università di Firenze and INFN Sezione di Firenze,Via G. Sansone 1, 50019 Sesto Fiorentino (Italy); Vescovi, E. [Institut für Physik, Humboldt-Universität zu Berlin, IRIS Adlershof, Zum Großen Windkanal 6, 12489 Berlin (Germany)
2016-02-16
We study the strong coupling behaviour of 1/4-BPS circular Wilson loops (a family of “latitudes') in N=4 Super Yang-Mills theory, computing the one-loop corrections to the relevant classical string solutions in AdS{sub 5}×S{sup 5}. Supersymmetric localization provides an exact result that, in the large ’t Hooft coupling limit, should be reproduced by the sigma-model approach. To avoid ambiguities due to the absolute normalization of the string partition function, we compare the ratio between the generic latitude and the maximal 1/2-BPS circle: any measure-related ambiguity should simply cancel in this way. We use the Gel’fand-Yaglom method with Dirichlet boundary conditions to calculate the relevant functional determinants, that present some complications with respect to the standard circular case. After a careful numerical evaluation of our final expression we still find disagreement with the localization answer: the difference is encoded into a precise “remainder function'. We comment on the possible origin and resolution of this discordance.
International Nuclear Information System (INIS)
Brzoska, A.M.; Lenz, F.; Thies, M.; Negele, J.W.
2005-01-01
A phenomenological analysis of the distribution of Wilson loops in SU(2) Yang-Mills theory is presented in which Wilson loop distributions are described as the result of a diffusion process on the group manifold. It is shown that, in the absence of forces, diffusion implies Casimir scaling and, conversely, exact Casimir scaling implies free diffusion. Screening processes occur if diffusion takes place in a potential. The crucial distinction between screening of fundamental and adjoint loops is formulated as a symmetry property related to the center symmetry of the underlying gauge theory. The results are expressed in terms of an effective Wilson loop action and compared with various limits of SU(2) Yang-Mills theory
One-Loop BPS amplitudes as BPS-state sums
Angelantonj, Carlo; Pioline, Boris
2012-01-01
Recently, we introduced a new procedure for computing a class of one-loop BPS-saturated amplitudes in String Theory, which expresses them as a sum of one-loop contributions of all perturbative BPS states in a manifestly T-duality invariant fashion. In this paper, we extend this procedure to all BPS-saturated amplitudes of the form \\int_F \\Gamma_{d+k,d} {\\Phi}, with {\\Phi} being a weak (almost) holomorphic modular form of weight -k/2. We use the fact that any such {\\Phi} can be expressed as a linear combination of certain absolutely convergent Poincar\\'e series, against which the fundamental domain F can be unfolded. The resulting BPS-state sum neatly exhibits the singularities of the amplitude at points of gauge symmetry enhancement, in a chamber-independent fashion. We illustrate our method with concrete examples of interest in heterotic string compactifications.
Toward precision holography with supersymmetric Wilson loops
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Faraggi, Alberto [Instituto de Física, Pontificia Universidad Católica de Chile,Casilla 306, Santiago (Chile); Zayas, Leopoldo A. Pando [The Abdus Salam International Centre for Theoretical Physics,Strada Costiera 11, 34014 Trieste (Italy); Michigan Center for Theoretical Physics, Department of Physics,University of Michigan, Ann Arbor, MI 48109 (United States); Silva, Guillermo A. [Instituto de Física de La Plata - CONICET & Departamento de Física - UNLP,C.C. 67, 1900 La Plata (Argentina); Trancanelli, Diego [Institute of Physics, University of São Paulo,05314-970 São Paulo (Brazil)
2016-04-11
We consider certain 1/4 BPS Wilson loop operators in SU(N)N=4 supersymmetric Yang-Mills theory, whose expectation value can be computed exactly via supersymmetric localization. Holographically, these operators are mapped to fundamental strings in AdS{sub 5}×S{sup 5}. The string on-shell action reproduces the large N and large coupling limit of the gauge theory expectation value and, according to the AdS/CFT correspondence, there should also be a precise match between subleading corrections to these limits. We perform a test of such match at next-to-leading order in string theory, by deriving the spectrum of quantum fluctuations around the classical string solution and by computing the corresponding 1-loop effective action. We discuss in detail the supermultiplet structure of the fluctuations. To remove a possible source of ambiguity in the ghost zero mode measure, we compare the 1/4 BPS configuration with the 1/2 BPS one, dual to a circular Wilson loop. We find a discrepancy between the string theory result and the gauge theory prediction, confirming a previous result in the literature. We are able to track the modes from which this discrepancy originates, as well as the modes that by themselves would give the expected result.
ABJM Wilson loops in arbitrary representations
International Nuclear Information System (INIS)
Hatsuda, Yasuyuki; Moriyama, Sanefumi; Okuyama, Kazumi
2013-06-01
We study vacuum expectation values (VEVs) of circular half BPS Wilson loops in arbitrary representations in ABJM theory. We find that those in hook representations are reduced to elementary integrations thanks to the Fermi gas formalism, which are accessible from the numerical studies similar to the partition function in the previous studies. For non-hook representations, we show that the VEVs in the grand canonical formalism can be exactly expressed as determinants of those in the hook representations. Using these facts, we can study the instanton effects of the VEVs in various representations. Our results are consistent with the worldsheet instanton effects studied from the topological string and a prescription to include the membrane instanton effects by shifting the chemical potential, which has been successful for the partition function.
ABJM Wilson loops in arbitrary representations
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Hatsuda, Yasuyuki [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany). Theory Group; Tokyo Institute of Technology (Japan). Dept. of Physics; Honda, Masazumi [High Energy Accelerator Research Organization (KEK), Tsukuba, Ibaraki (Japan); Moriyama, Sanefumi [Nagoya Univ. (Japan). Kobayashi Maskawa Inst. and Graduate School of Mathematics; Okuyama, Kazumi [Shinshu Univ., Matsumoto, Nagano (Japan). Dept. of Physics
2013-06-15
We study vacuum expectation values (VEVs) of circular half BPS Wilson loops in arbitrary representations in ABJM theory. We find that those in hook representations are reduced to elementary integrations thanks to the Fermi gas formalism, which are accessible from the numerical studies similar to the partition function in the previous studies. For non-hook representations, we show that the VEVs in the grand canonical formalism can be exactly expressed as determinants of those in the hook representations. Using these facts, we can study the instanton effects of the VEVs in various representations. Our results are consistent with the worldsheet instanton effects studied from the topological string and a prescription to include the membrane instanton effects by shifting the chemical potential, which has been successful for the partition function.
Wilson loops, instantons and quantum mechanics
International Nuclear Information System (INIS)
Schiereck, Marc
2014-05-01
In this thesis we examine two different problems. The first is the computation of vacuum expectation values of Wilson loop operators in ABJM theory, the other problem is finding the instanton series of the refined topological string on certain local Calabi-Yau geometries in the Nekrasov-Shatashvili limit. Based on the description of ABJM theory as a matrix model, it is possible to find a description of it in terms of an ideal Fermi gas with a non-trivial one-particle Hamiltonian. The vacuum-expectation-values of Wilson loop operators in ABJM theory correspond to averages of operators in the statistical-mechanical problem. Using the WKB expansion, it is possible to extract the full 1/N expansion of the vevs, up to exponentially small contributions, for arbitrary Chern-Simons coupling. We compute these vevs for the 1/6 and 1/2 BPS Wilson loops at any winding number. These can be written in terms of the Airy function. The expressions we found reproduce the low genus results previously obtained in the 't Hooft expansion. In another problem we use mirror symmetry, quantum geometry and modularity properties of elliptic curves to calculate the refined free energies, given in terms of an instanton sum, in the Nekrasov-Shatashvili limit on non-compact toric Calabi-Yau manifolds, based on del Pezzo surfaces. Quantum geometry here is to be understood as a quantum deformed version of rigid special geometry, which has its origin in the quantum mechanical behavior of branes in the topological string B-model. We argue that in the Seiberg-Witten picture only the Coulomb parameters lead to quantum corrections, while the mass parameters remain uncorrected. In certain cases we also compute the expansion of the free energies at the orbifold point and the conifold locus. We compute the quantum corrections order by order on ℎ by deriving second order differential operators, which act on the classical periods.
Perturbation calculations with Wilson loop
International Nuclear Information System (INIS)
Peixoto Junior, L.B.
1984-01-01
We present perturbative calculations with the Wilson loop (WL). The dimensional regularization method is used with a special attention concerning to the problem of divergences in the WL expansion in second and fourth orders, in three and four dimensions. We show that the residue in the pole, in 4d, of the fourth order graphs contribution sum is important for the charge renormalization. We compute up to second order the exact expression of the WL, in three-dimensional gauge theories with topological mass as well as its assimptotic behaviour for small and large distances. the author [pt
The Wilson loop and some applications
International Nuclear Information System (INIS)
Bezerra, V.B.
1983-04-01
A simple relation between the classical Wilson loop and the angular deviation in the parallel displacement is found. An example of potentials which give field copies and which suplly the same classical Wilson loop for a particular trajectory is exhibited. The asymptotic behaviour of the Wilson loop for the BPST instanton and the meron, is discussed. By using the dimensional regularization technique to calculate the second order term of the quantum Wilson loop, the influence of geometrical factors for the residue in the pole due to contact points, cuspides and intersections, in function of the space-time ν, is investigated. Charge renormalization in Quantum electrodynamics is finally calculated by using the quantum Wilson loop. (L.C.) [pt
The Wilson loop and some applications
International Nuclear Information System (INIS)
Bezerra, V.B.
1983-01-01
A simple relation between the classical Wilson loop and the angular deviation in the parallel shift is found. An example of potential which given field copies and which give the same classical Wilson loop for a given trajectory is exchibited. Afterwards, the asymptotic behaviour of the Wilson loop for the BPST instanton and meron is discussed. Using the dimensional regularization technique to calculate the second order term of Quantum Wilson loop, the influence of geometrical factors for the residue in the polo due to contact points, cusp and intersections, in function of the upsilon dimension of the space-time is investigated. Finally, the charge renormalization in Quantum Electrodynamics using Quantum Wilson loop is calculated. (L.C.) [pt
Wilson loops in 3d {N} = 4 SQCD from Fermi gas
Okuyama, Kazumi
2016-11-01
We study 1/2 BPS Wilson loops in 3d {N} = 4 U( N ) Yang-Mills theory with one adjoint and N f fundamental hypermultiplets from the Fermi gas approach. By numerical fitting, we find the first few worldsheet instanton corrections to the Wilson loops with winding numbers 1, 2 and 3. We verify that our Fermi gas results are consistent with the matrix model results in the planar limit.
Eigenvalue distributions of Wilson loops
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Lohmayer, Robert
2010-07-01
In the first part of this thesis, we focus on the distribution of the eigenvalues of the unitary Wilson loop matrix in the two-dimensional case at arbitrary finite N. To characterize the distribution of the eigenvalues, we introduce three density functions (the ''symmetric'', the ''antisymmetric'', and the ''true'' eigenvalue density) which differ at finite N but possess the same infinite-N limit, exhibiting the Durhuus-Olesen phase transition. Using expansions of determinants and inverse determinants in characters of totally symmetric or totally antisymmetric representations of SU(N), the densities at finite N can be expressed in terms of simple sums involving only dimensions and quadratic Casimir invariants of certain irreducible representations of SU(N), allowing for a numerical computation of the densities at arbitrary N to any desired accuracy. We find that the true eigenvalue density, adding N oscillations to the monotonic symmetric density, is in some sense intermediate between the symmetric and the antisymmetric density, which in turn is given by a sum of N delta peaks located at the zeros of the average of the characteristic polynomial. Furthermore, we show that the dependence on N can be made explicit by deriving integral representations for the resolvents associated to the three eigenvalue densities. Using saddle-point approximations, we confirm that all three densities reduce to the Durhuus-Olesen result in the infinite-N limit. In the second part, we study an exponential form of the multiplicative random complex matrix model introduced by Gudowska-Nowak et al. Varying a parameter which can be identified with the area of the Wilson loop in the unitary case, the region of non-vanishing eigenvalue density of the N-dimensional complex product matrix undergoes a topological change at a transition point in the infinite-N limit. We study the transition by a detailed analysis of the average of the
Eigenvalue distributions of Wilson loops
International Nuclear Information System (INIS)
Lohmayer, Robert
2010-01-01
In the first part of this thesis, we focus on the distribution of the eigenvalues of the unitary Wilson loop matrix in the two-dimensional case at arbitrary finite N. To characterize the distribution of the eigenvalues, we introduce three density functions (the ''symmetric'', the ''antisymmetric'', and the ''true'' eigenvalue density) which differ at finite N but possess the same infinite-N limit, exhibiting the Durhuus-Olesen phase transition. Using expansions of determinants and inverse determinants in characters of totally symmetric or totally antisymmetric representations of SU(N), the densities at finite N can be expressed in terms of simple sums involving only dimensions and quadratic Casimir invariants of certain irreducible representations of SU(N), allowing for a numerical computation of the densities at arbitrary N to any desired accuracy. We find that the true eigenvalue density, adding N oscillations to the monotonic symmetric density, is in some sense intermediate between the symmetric and the antisymmetric density, which in turn is given by a sum of N delta peaks located at the zeros of the average of the characteristic polynomial. Furthermore, we show that the dependence on N can be made explicit by deriving integral representations for the resolvents associated to the three eigenvalue densities. Using saddle-point approximations, we confirm that all three densities reduce to the Durhuus-Olesen result in the infinite-N limit. In the second part, we study an exponential form of the multiplicative random complex matrix model introduced by Gudowska-Nowak et al. Varying a parameter which can be identified with the area of the Wilson loop in the unitary case, the region of non-vanishing eigenvalue density of the N-dimensional complex product matrix undergoes a topological change at a transition point in the infinite-N limit. We study the transition by a detailed analysis of the average of the modulus square of the characteristic polynomial. Furthermore
Probing Wilson loops in N=4 Chern–Simons-matter theories at weak coupling
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Luca Griguolo
2016-02-01
Full Text Available For three-dimensional N=4 super-Chern–Simons-matter theories associated to necklace quivers U(N0×U(N1×⋯U(N2r−1, we study at quantum level the two kinds of 1/2 BPS Wilson loop operators recently introduced in arXiv:1506.07614. We perform a two-loop evaluation and find the same result for the two kinds of operators, so moving to higher loops a possible quantum uplift of the classical degeneracy. We also compute the 1/4 BPS bosonic Wilson loop and discuss the quantum version of the cohomological equivalence between fermionic and bosonic Wilson loops. We compare the perturbative result with the Matrix Model prediction and find perfect matching, after identification and remotion of a suitable framing factor. Finally, we discuss the potential appearance of three-loop contributions that might break the classical degeneracy and briefly analyze possible implications on the BPS nature of these operators.
Symmetric Wilson Loops beyond leading order
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Xinyi Chen-Lin
2016-12-01
Full Text Available We study the circular Wilson loop in the symmetric representation of U(N in $\\mathcal{N} = 4$ super-Yang-Mills (SYM. In the large N limit, we computed the exponentially-suppressed corrections for strong coupling, which suggests non-perturbative physics in the dual holographic theory. We also computed the next-to-leading order term in 1/N, and the result matches with the exact result from the k-fundamental representation.
Phase transition of anti-symmetric Wilson loops in N=4 SYM
Okuyama, Kazumi
2017-12-01
We will argue that the 1/2 BPS Wilson loops in the anti-symmetric representations in the N=4 super Yang-Mills (SYM) theory exhibit a phase transition at some critical value of the 't Hooft coupling of order N 2. In the matrix model computation of Wilson loop expectation values, this phase transition corresponds to the transition between the one-cut phase and the two-cut phase. It turns out that the one-cut phase is smoothly connected to the small 't Hooft coupling regime and the 1/ N corrections of Wilson loops in this phase can be systematically computed from the topological recursion in the Gaussian matrix model.
Antisymmetric Wilson loops in N = 4 SYM beyond the planar limit
Gordon, James
2018-01-01
We study the 1/2 -BPS circular Wilson loop in the totally antisymmetric representation of the gauge group in N = 4 supersymmetric Yang-Mills. This observable is captured by a Gaussian matrix model with appropriate insertion. We compute the first 1 /N correction at leading order in 't Hooft coupling by means of the matrix model loop equations. Disagreement with the 1-loop effective action of the holographically dual D5-brane suggests the need to account for gravitational backreaction on the string theory side.
Wilson loop's phase transition probed by non-local observable
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Hui-Ling Li
2018-04-01
Full Text Available In order to give further insights into the holographic Van der Waals phase transition, it would be of great interest to investigate the behavior of Wilson loop across the holographic phase transition for a higher dimensional hairy black hole. We offer a possibility to proceed with a numerical calculation in order to discussion on the hairy black hole's phase transition, and show that Wilson loop can serve as a probe to detect a phase structure of the black hole. Furthermore, for a first order phase transition, we calculate numerically the Maxwell's equal area construction; and for a second order phase transition, we also study the critical exponent in order to characterize the Wilson loop's phase transition.
Strings in bubbling geometries and dual Wilson loop correlators
Aguilera-Damia, Jeremías; Correa, Diego H.; Fucito, Francesco; Giraldo-Rivera, Victor I.; Morales, Jose F.; Pando Zayas, Leopoldo A.
2017-12-01
We consider a fundamental string in a bubbling geometry of arbitrary genus dual to a half-supersymmetric Wilson loop in a general large representation R of the SU( N) gauge group in N=4 Supersymmetric Yang-Mills. We demonstrate, under some mild conditions, that the minimum value of the string classical action for a bubbling geometry of arbitrary genus precisely matches the correlator of a Wilson loop in the fundamental representation and one in a general large representation. We work out the case in which the large representation is given by a rectangular Young tableau, corresponding to a genus one bubbling geometry, explicitly. We also present explicit results in the field theory for a correlator of two Wilson loops: a large one in an arbitrary representation and a "small" one in the fundamental, totally symmetric or totally antisymmetric representation.
Scattering amplitudes and Wilson loops in twistor space
Adamo, Tim; Bullimore, Mathew; Mason, Lionel; Skinner, David
2011-11-01
This paper reviews the recent progress in twistor approaches to Wilson loops, amplitudes and their duality for {N}=4 super-Yang-Mills. Wilson loops and amplitudes are derived from first principles using the twistor action for maximally supersymmetric Yang-Mills theory. We start by deriving the MHV rules for gauge theory amplitudes from the twistor action in an axial gauge in twistor space, and show that this gives rise to the original momentum space version given by Cachazo, Svrček and Witten. We then go on to obtain from these the construction of the momentum twistor space loop integrand using (planar) MHV rules and show how it arises as the expectation value of a holomorphic Wilson loop in twistor space. We explain the connection between the holomorphic Wilson loop and certain light-cone limits of correlation functions. We give a brief review of other ideas in connection with amplitudes in twistor space: twistor-strings, recursion in twistor space, the Grassmannian residue formula for leading singularities and amplitudes as polytopes. This paper is an invited review for a special issue of Journal of Physics A: Mathematical and Theoretical devoted to ‘Scattering amplitudes in gauge theories’.
OPE for null Wilson loops and open spin chains
Belitsky, A. V.
2012-03-01
Maximal helicity-violating scattering amplitudes in N = 4 supersymmetric Yang-Mills theory are dual to Wilson loops on closed null polygons. We perform their operator product expansion analysis in two-dimensional kinematics in the soft-collinear approximation which corresponds to the case when some light-cone distances vanish. We construct the expansion in terms of multi-particle "heavy"-light operators, where the "heavy" fields are identified with the Wilson lines defining the OPE channel and the light fields emerge from the curvature of the contour. The correlation function of these define the remainder function. We study the dilatation operator for these operators at one-loop order and find that it corresponds to a non-compact open spin chain. This provides an alternative view on elementary excitations propagating on the GKP string at weak coupling, which now correspond to particles traveling along an open spin chain. The factorized structure of the Wilson loop in the soft limit allows one to represent the two-loop correction to the octagon Wilson loop as a convolution formula and find the corresponding remainder function.
Scattering amplitudes and Wilson loops in twistor space
Energy Technology Data Exchange (ETDEWEB)
Adamo, Tim; Mason, Lionel [Mathematical Institute, 24-29 St. Giles' , Oxford OX1 3LB (United Kingdom); Bullimore, Mathew [Rudolf Peierls Centre for Theoretical Physics, 1 Keble Road, Oxford OX1 3NP (United Kingdom); Skinner, David, E-mail: adamo@maths.ox.ac.uk [Perimeter Institute for Theoretical Physics, 31 Caroline Street North, Waterloo, Ontario N2 L 2Y5 (Canada)
2011-11-11
This paper reviews the recent progress in twistor approaches to Wilson loops, amplitudes and their duality for N=4 super-Yang-Mills. Wilson loops and amplitudes are derived from first principles using the twistor action for maximally supersymmetric Yang-Mills theory. We start by deriving the MHV rules for gauge theory amplitudes from the twistor action in an axial gauge in twistor space, and show that this gives rise to the original momentum space version given by Cachazo, Svrcek and Witten. We then go on to obtain from these the construction of the momentum twistor space loop integrand using (planar) MHV rules and show how it arises as the expectation value of a holomorphic Wilson loop in twistor space. We explain the connection between the holomorphic Wilson loop and certain light-cone limits of correlation functions. We give a brief review of other ideas in connection with amplitudes in twistor space: twistor-strings, recursion in twistor space, the Grassmannian residue formula for leading singularities and amplitudes as polytopes. This paper is an invited review for a special issue of Journal of Physics A: Mathematical and Theoretical devoted to 'Scattering amplitudes in gauge theories'. (review)
Wilson loops en la correspondencia AdS/CFT
Aguilera Damia, Jeremías
2017-01-01
Esta tesis está abocada al estudio de operadores no locales e invariantes de gauge, denominados Wilson loops, tanto a través de técnicas propias de teoría de cuerdas como por medio de técnicas avanzadas en teorías de gauge.
Energy Technology Data Exchange (ETDEWEB)
Forini, V. [Institut für Physik, Humboldt-Universität zu Berlin, IRIS Adlershof,Zum Großen Windkanal 6, 12489 Berlin (Germany); Tseytlin, A.A. [Theoretical Physics Group, Blackett Laboratory, Imperial College,London, SW7 2AZ (United Kingdom); Vescovi, E. [Institut für Physik, Humboldt-Universität zu Berlin, IRIS Adlershof,Zum Großen Windkanal 6, 12489 Berlin (Germany); Institute of Physics, University of São Paulo,Rua do Matão 1371, 05508-090 São Paulo (Brazil)
2017-03-01
We revisit the computation of the 1-loop string correction to the “latitude' minimal surface in AdS{sub 5}×S{sup 5} representing 1/4 BPS Wilson loop in planar N=4 SYM theory previously addressed in https://arxiv.org/abs/1512.00841 and https://arxiv.org/abs/1601.04708. We resolve the problem of matching with the subleading term in the strong coupling expansion of the exact gauge theory result (derived previously from localization) using a different method to compute determinants of 2d string fluctuation operators. We apply perturbation theory in a small parameter (angle of the latitude) corresponding to an expansion near the AdS{sub 2} minimal surface representing 1/2 BPS circular Wilson loop. This allows us to compute the corrections to the heat kernels and zeta-functions of the operators in terms of the known heat kernels on AdS{sub 2}. We apply the same method also to two other examples of Wilson loop surfaces: generalized cusp and k-wound circle.
Wilson-loop symmetry breaking reexamined
International Nuclear Information System (INIS)
Nakamura, A.; Shiraishi, K.
1988-07-01
The splitting in the energy of gauge field vacua on non-simply connected space S 3 /Z 2 is reconsidered. We show the calculation to the one-loop level for a Yang-Mills vector with a ghost field. We confirm our previous result and give a solution to the question offered by Freire, Romao and Barroso. (author)
Wilson loop invariants from WN conformal blocks
Directory of Open Access Journals (Sweden)
Oleg Alekseev
2015-12-01
Full Text Available Knot and link polynomials are topological invariants calculated from the expectation value of loop operators in topological field theories. In 3D Chern–Simons theory, these invariants can be found from crossing and braiding matrices of four-point conformal blocks of the boundary 2D CFT. We calculate crossing and braiding matrices for WN conformal blocks with one component in the fundamental representation and another component in a rectangular representation of SU(N, which can be used to obtain HOMFLY knot and link invariants for these cases. We also discuss how our approach can be generalized to invariants in higher-representations of WN algebra.
Planar and non-planar Wilson loops in QCD
International Nuclear Information System (INIS)
Bagan, E.; Latorre, J.I.; Massachusetts Inst. of Tech., Cambridge
1988-01-01
A general QCD sum rule calculation of vacuum expectation values of Wilson loops is presented and particularized to several specific planar and non-planar contours. The string tension obtained is √σ = 0.50(5) GeV. Within the errors of the approach, this result is shape-independent. We comment on the possibility that corrections to the area and perimeter laws could be parametrized by a geodesic curvature term. (orig.)
Comments on higher rank Wilson loops in N = 2∗
Liu, James T.; Zayas, Leopoldo A. Pando; Zhou, Shan
2018-01-01
For N = 2∗ theory with U( N ) gauge group we evaluate expectation values of Wilson loops in representations described by a rectangular Young tableau with n rows and k columns. The evaluation reduces to a two-matrix model and we explain, using a combination of numerical and analytical techniques, the general properties of the eigen-value distributions in various regimes of parameters ( N, λ , n, k) where λ is the 't Hooft coupling. In the large N limit we present analytic results for the leading and sub-leading contributions. In the particular cases of only one row or one column we reproduce previously known results for the totally symmetry and totally antisymmetric representations. We also extensively discusss the N = 4 limit of the N = 2∗ theory. While establishing these connections we clarify aspects of various orders of limits and how to relax them; we also find it useful to explicitly address details of the genus expansion. As a result, for the totally symmetric Wilson loop we find new contributions that improve the comparison with the dual holographic computation at one loop order in the appropriate regime.
String corrections to circular Wilson loop and anomalies
Cagnazzo, Alessandra; Medina-Rincon, Daniel; Zarembo, Konstantin
2018-02-01
We study string quantum corrections to the ratio of latitude and circular Wilson loops in N = 4 super-Yang-Mills theory at strong coupling. Conformal gauge for the corresponding minimal surface in AdS5 × S 5 is singular and we show that an IR anomaly associated with the divergence in the conformal factor removes previously reported discrepancy with the exact field-theory result. We also carefully check conformal anomaly cancellation and recalculate fluctuation determinants by directly evaluting phaseshifts for all the fluctuation modes.
Dual conformal transformations of smooth holographic Wilson loops
Energy Technology Data Exchange (ETDEWEB)
Dekel, Amit [Nordita, KTH Royal Institute of Technology and Stockholm University, Roslagstullsbacken 23, SE-106 91 Stockholm (Sweden)
2017-01-19
We study dual conformal transformations of minimal area surfaces in AdS{sub 5}×S{sup 5} corresponding to holographic smooth Wilson loops and some other related observables. To act with dual conformal transformations we map the string solutions to the dual space by means of T-duality, then we apply a conformal transformation and finally T-dualize back to the original space. The transformation maps between string solutions with different boundary contours. The boundary contours of the minimal surfaces are not mapped back to the AdS boundary, and the regularized area of the surface changes.
Correlation function of null polygonal Wilson loops with local operators
Alday, L. F.; Buchbinder, E. I.; Tseytlin, A. A.
2011-01-01
We consider the correlator of a light-like polygonal Wilson loop with n cusps with a local operator (like the dilaton or the chiral primary scalar) in planar N =4 super Yang-Mills theory. As a consequence of conformal symmetry, the main part of such correlator is a function F of 3n-11 conformal ratios. The first non-trivial case is n=4 when F depends on just one conformal ratio \\zeta. This makes the corresponding correlator one of the simplest non-trivial observables that one would like to c...
Higher rank ABJM Wilson loops from matrix models
Energy Technology Data Exchange (ETDEWEB)
Cookmeyer, Jonathan [Haverford College,370 Lancaster Avenue, Haverford, PA, 19041 (United States); Liu, James T. [Michigan Center for Theoretical Physics, Department of Physics, University of Michigan,450 Church Street, Ann Arbor, MI, 48109 (United States); Zayas, Leopoldo A. Pando [The Abdus Salam International Centre for Theoretical Physics,Strada Costiera 11, Trieste, 34014 (Italy)
2016-11-21
We compute the vacuum expectation values of 1/6 supersymmetric Wilson loops in higher dimensional representations of the gauge group in ABJM theory. We present results for the m-symmetric and m-antisymmetric representations by exploiting standard matrix model techniques. At leading order, in the saddle point approximation, our expressions reproduce holographic results from both D6 and D2 branes corresponding to the antisymmetric and symmetric representations, respectively. We also compute 1/N corrections to the leading saddle point results.
Higher Rank ABJM Wilson Loops from Matrix Models
Cookmeyer, Jonathan; Liu, James; Zayas, Leopoldo
2017-01-01
We compute the expectation values of 1/6 supersymmetric Wilson Loops in ABJM theory in higher rank representations. Using standard matrix model techniques, we calculate the expectation value in the rank m fully symmetric and fully antisymmetric representation where m is scaled with N. To leading order, we find agreement with the classical action of D6 and D2 branes in AdS4 ×CP3 respectively. Further, we compute the first subleading order term, which, on the AdS side, makes a prediction for the one-loop effective action of the corresponding D6 and D2 branes. Supported by the National Science Foundation under Grant No. PHY 1559988 and the US Department of Energy under Grant No. DE-SC0007859.
Holographic Wilson loops, dielectric interfaces, and topological insulators
Estes, John; O'Bannon, Andy; Tsatis, Efstratios; Wrase, Timm
2013-05-01
We use holography to study (3+1)-dimensional N=4 supersymmetric SU(Nc) Yang-Mills theory (SYM) in the large-Nc and large-coupling limits, with a (2+1)-dimensional interface where the Yang-Mills coupling or θ angle changes value, or “jumps.” We consider interfaces that either break all supersymmetry or that preserve half of the N=4 supersymmetry thanks to certain operators localized to the interface. Specifically, we compute the expectation values of a straight timelike Wilson line and of a rectangular Wilson loop in the fundamental representation of SU(Nc). The former gives us the self-energy of a heavy test charge while the latter gives us the potential between heavy test charges. A jumping coupling or θ angle acts much like a dielectric interface in electromagnetism: the self-energy or potential includes the effects of image charges. N=4 SYM with a jumping θ angle may also be interpreted as the low-energy effective description of a fractional topological insulator, as we explain in detail. For nonsupersymmetric interfaces, we find that the self-energy and potential are qualitatively similar to those in electromagnetism, despite the differences between N=4 SYM and electromagnetism. For supersymmetric interfaces, we find dramatic differences from electromagnetism which depend sensitively on the coupling of the test charge to the adjoint scalars of N=4 SYM. In particular, we find one special case where a test charge has a vanishing image charge.
Circular Wilson loops in defect conformal field theory
Energy Technology Data Exchange (ETDEWEB)
Aguilera-Damia, Jeremías; Correa, Diego H. [Instituto de Física La Plata, CONICET, Universidad Nacional de La Plata,C.C. 67, 1900 La Plata (Argentina); Giraldo-Rivera, Victor I. [International Centre for Theoretical Sciences (ICTS-TIFR),Shivakote, Hesaraghatta Hobli, Bengaluru 560089 (India)
2017-03-06
We study a D3-D5 system dual to a conformal field theory with a codimension-one defect that separates regions where the ranks of the gauge groups differ by k. With the help of this additional parameter, as observed by Nagasaki, Tanida and Yamaguchi, one can define a double scaling limit in which the quantum corrections are organized in powers of λ/k{sup 2}, which should allow to extrapolate results between weak and strong coupling regimes. In particular we consider a radius R circular Wilson loop placed at a distance L, whose internal space orientation is given by an angle χ. We compute its vacuum expectation value and show that, in the double scaling limit and for small χ and small L/R, weak coupling results can be extrapolated to the strong coupling limit.
Non-supersymmetric Wilson loop in N = 4 SYM and defect 1d CFT
Beccaria, Matteo; Giombi, Simone; Tseytlin, Arkady A.
2018-03-01
Following Polchinski and Sully (arXiv:1104.5077), we consider a generalized Wilson loop operator containing a constant parameter ζ in front of the scalar coupling term, so that ζ = 0 corresponds to the standard Wilson loop, while ζ = 1 to the locally supersymmetric one. We compute the expectation value of this operator for circular loop as a function of ζ to second order in the planar weak coupling expansion in N = 4 SYM theory. We then explain the relation of the expansion near the two conformal points ζ = 0 and ζ = 1 to the correlators of scalar operators inserted on the loop. We also discuss the AdS5 × S 5 string 1-loop correction to the strong-coupling expansion of the standard circular Wilson loop, as well as its generalization to the case of mixed boundary conditions on the five-sphere coordinates, corresponding to general ζ. From the point of view of the defect CFT1 defined on the Wilson line, the ζ-dependent term can be seen as a perturbation driving a RG flow from the standard Wilson loop in the UV to the supersymmetric Wilson loop in the IR. Both at weak and strong coupling we find that the logarithm of the expectation value of the standard Wilson loop for the circular contour is larger than that of the supersymmetric one, which appears to be in agreement with the 1d analog of the F-theorem.
Wilson loop correlators at strong coupling: from matrices to bubbling geometries
Gomis, Jaume; Matsuura, Shunji; Okuda, Takuya; Trancanelli, Diego
2008-08-01
We compute at strong coupling the large N correlation functions of supersymmetric Wilson loops in large representations of the gauge group with local operators of Script N = 4 super Yang-Mills. The gauge theory computation of these correlators is performed using matrix model techniques. We show that the strong coupling correlator of the Wilson loop with the stress tensor computed using the matrix model exactly matches the semiclassical computation of the correlator of the 't Hooft loop with the stress tensor, providing a non-trivial quantitative test of electric-magnetic duality of Script N = 4 super Yang-Mills. We then perform these calculations using the dual bulk gravitational picture, where the Wilson loop is described by a ``bubbling'' geometry. By applying holographic methods to these backgrounds we calculate the Wilson loop correlation functions, finding perfect agreement with our gauge theory results.
Anticommuting variables, internal degrees of freedom, and the Wilson loop
International Nuclear Information System (INIS)
Barducci, A.; Casalbuoni, R.; Lusanna, L.
1981-01-01
In this paper we show that is possible to give a real physical meaning to theories in which internal degrees of freedom are described by Grassmann variables. The physical theory is defined by means of an averaging procedure in terms of a distribution function in the Grassmann restricted space satisfying all the physical requirements. If we use this result for a scalar particle with inner degrees of freedom (electric charge, colour, ...) interacting with Yang-Mills gauge fields, it turns out that we can define two different classical theories. Taking the average of the coupled particle-field equations of motion, we recover the usual classical theory. Taking instead the average of the solution of such equations we get a theory which is free from all the classical infinities (and so of the causal defects, like runaway solution or pre-acceleration) but also of all the effects of the same order in the charges (like radiation). The main point is that the processes of averaging and integrating the equations of motion do not commute. Then for the case of colour degrees of freedom we study the quantization of the theory by the path-integral method and we show that the functional integration can be done for an arbitrary gluon field simply by using the classical solution. As a result we obtain an expression for the Wilson loop as a functional integral for the internal fermionic degrees of freedom. (orig.)
Wilson loop and dimensional reduction in noncommutative gauge theories
Lee, Sunggeun; Sin, Sang-Jin
2001-10-01
Using the anti-de Sitter (AdS) conformal field theory correspondence we study the UV behavior of Wilson loops in various noncommutative gauge theories. We get an area law in most cases and try to identify its origin. In the D3 case, we may identify the the origin as the D1 dominance over the D3: as we go to the boundary of AdS space, the effect of the flux of the D3 charge is highly suppressed, while the flux due to the D1 charge is enhanced. So near the boundary the theory is more like a theory on a D1-brane than that on a D3-brane. This phenomena is closely related to dimensional reduction due to the strong magnetic field in the charged particle in the magnetic field. The linear potential is not due to the confinement by IR effect but is the analogue of Coulomb's potential in 1+1 dimensions.
Wilson Loop and related strings for the instanton and their variational derivatives
International Nuclear Information System (INIS)
Bollini, C.G.; Giambiagi, J.J.; Tiomno, J.
1980-05-01
Ordered integrals along arcs (or circles) and segments for the instanton are computed. They are to obtain variational and partial derivatives for open an d closed strings. The D'Alembertian for wilson loops is also computed. (Author) [pt
Some remarks about the classical Wilson loop for a class of gauge field copies
International Nuclear Information System (INIS)
Bezerra, V.B.
1984-01-01
Ordered integrals along circles for a class of potentials that given the same field strength are computed. The asymptotic behaviour of the Wilson Loop associated to these potentials is discussed. (Author) [pt
Operator product expansion of higher rank Wilson loops from D-branes and matrix models
International Nuclear Information System (INIS)
Giombi, Simone; Ricci, Riccardo; Trancanelli, Diego
2006-01-01
In this paper we study correlation functions of circular Wilson loops in higher dimensional representations with chiral primary operators of N = 4 super Yang-Mills theory. This is done using the recently established relation between higher rank Wilson loops in gauge theory and D-branes with electric fluxes in supergravity. We verify our results with a matrix model computation, finding perfect agreement in both the symmetric and the antisymmetric case
All three-loop four-point correlators of half-BPS operators in planar $ \\mathcal{N} $ = 4 SYM
Chicherin, Dmitry; Heslop, Paul; Sokatchev, Emery
2016-01-01
We obtain the planar correlation function of four half-BPS operators of arbitrary weights, up to three loops. Our method exploits only elementary properties of the integrand of the planar correlator, such as its symmetries and singularity structure. This allows us to write down a general ansatz for the integrand. The coefficients in the ansatz are fixed by means of a powerful light-cone OPE relation between correlators with different weights. Our result is formulated in terms of a limited number of functions built from known one-, two- and three-loop conformal integrals. These results are useful for checking recent integrability predictions for the OPE structure constants.
Scaling properties of Wilson loops pierced by P-vortices
DEFF Research Database (Denmark)
Dunn, Patrick; Greensite, Jeffrey Paul
2012-01-01
these ratios are plotted versus loop area in physical units, for a range of lattice couplings, it is found that the points fall approximately on a single curve, consistent with scaling. We also find that the ratios are rather insensitive to the point where the minimal area of the loop is pierced by the P-vortex....
Holographic calculations of Euclidean Wilson loop correlator in Euclidean anti-de Sitter space
Energy Technology Data Exchange (ETDEWEB)
Ziama, Sannah [Department of Physics and Astronomy, University of Kentucky,505 Rose Street, Lexington, KY 40506-0055 (United States)
2015-04-07
The correlation functions of two or more Euclidean Wilson loops of various shapes in Euclidean anti-de Sitter space are computed by considering the minimal area surfaces connecting the loops. The surfaces are parametrized by Riemann theta functions associated with genus three hyperelliptic Riemann surfaces. In the case of two loops, the distance L by which they are separated can be adjusted by continuously varying a specific branch point of the auxiliary Riemann surface. When L is much larger than the characteristic size of the loops, then the loops are approximately regarded as local operators and their correlator as the correlator of two local operators. Similarly, when a loop is very small compared to the size of another loop, the small loop is considered as a local operator corresponding to a light supergravity mode.
Minimal area surfaces dual to Wilson loops and the Mathieu equation
Energy Technology Data Exchange (ETDEWEB)
Huang, Changyu; He, Yifei; Kruczenski, Martin [Department of Physics and Astronomy, Purdue University, 525 Northwestern Avenue, W. Lafayette, IN, 47907-2036 (United States)
2016-08-11
The AdS/CFT correspondence relates Wilson loops in N=4 SYM to minimal area surfaces in AdS{sub 5}×S{sup 5} space. Recently, a new approach to study minimal area surfaces in AdS{sub 3}⊂AdS{sub 5} was discussed based on a Schroedinger equation with a periodic potential determined by the Schwarzian derivative of the shape of the Wilson loop. Here we use the Mathieu equation, a standard example of a periodic potential, to obtain a class of Wilson loops such that the area of the dual minimal area surface can be computed analytically in terms of eigenvalues of such equation. As opposed to previous examples, these minimal surfaces have an umbilical point (where the principal curvatures are equal) and are invariant under λ-deformations. In various limits they reduce to the single and multiple wound circular Wilson loop and to the regular light-like polygons studied by Alday and Maldacena. In this last limit, the periodic potential becomes a series of deep wells each related to a light-like segment. Small corrections are described by a tight-binding approximation. In the circular limit they are well approximated by an expansion developed by A. Dekel. In the particular case of no umbilical points they reduce to a previous solution proposed by J. Toledo. The construction works both in Euclidean and Minkowski signature of AdS{sub 3}.
Minimal area surfaces dual to Wilson loops and the Mathieu equation
Huang, Changyu; He, Yifei; Kruczenski, Martin
2016-08-01
The AdS/CFT correspondence relates Wilson loops in {N}=4 SYM to minimal area surfaces in AdS 5 × S 5 space. Recently, a new approach to study minimal area surfaces in AdS 3 ⊂ AdS 5 was discussed based on a Schroedinger equation with a periodic potential determined by the Schwarzian derivative of the shape of the Wilson loop. Here we use the Mathieu equation, a standard example of a periodic potential, to obtain a class of Wilson loops such that the area of the dual minimal area surface can be computed analytically in terms of eigenvalues of such equation. As opposed to previous examples, these minimal surfaces have an umbilical point (where the principal curvatures are equal) and are invariant under λ-deformations. In various limits they reduce to the single and multiple wound circular Wilson loop and to the regular light-like polygons studied by Alday and Maldacena. In this last limit, the periodic potential becomes a series of deep wells each related to a light-like segment. Small corrections are described by a tight-binding approximation. In the circular limit they are well approximated by an expansion developed by A. Dekel. In the particular case of no umbilical points they reduce to a previous solution proposed by J. Toledo. The construction works both in Euclidean and Minkowski signature of AdS 3.
Recent results on the 3-loop heavy flavor Wilson coefficients in deep-inelastic scattering
Energy Technology Data Exchange (ETDEWEB)
Bluemlein, J.; Freitas A. de; Raab, C.; Wissbrock, F. [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany); Ablinger, J.; Hasselhuhn, A.; Round, M.; Schneider, C. [Johannes Kepler Univ., Linz (Austria). Research Inst. for Symbolic Computation; Manteuffel, A. von [Mainz Univ. (Germany). PRISMA Cluster of Excellence; Mainz Univ. (Germany). Inst. fuer Physik
2013-07-15
We report on recent progress in the calculation of the 3-loop massive Wilson coefficients in deep-inelastic scattering at general values of N for neutral and charged current reactions in the asymptotic region Q{sup 2}>>m{sup 2}.
The Wilson loop in Yang-Mills theory in the general axial gauge
Hand, B J; Hand, Brian J; Leibbrandt, George
1995-01-01
We test the unified-gauge formalism by computing a Wilson loop in Yang-Mills theory to one-loop order. The unified-gauge formalism is characterized by the abritrary, but fixed, four-vector N_\\mu, which collectively represents the light-cone gauge (N^2 = 0), the temporal gauge (N^2 > 0), the pure axial gauge (N^2 < 0) and the planar gauge (N^2 < 0). A novel feature of the calculation is the use of distinct sets of vectors, \\{ n_{\\mu}, n_{\\mu}^{\\ast} \\} and \\{N_{\\mu}, N_{\\mu}^{\\ast}\\}, for the path and for the gauge-fixing constraint, respectively. The answer for the Wilson loop is independent of N_{\\mu}, and agrees numerically with the result obtained in the Feymman gauge.
3-loop heavy flavor Wilson coefficients in deep-inelastic scattering
International Nuclear Information System (INIS)
Ablinger, J.; Hasselhuhn, A.; Schneider, C.; Manteuffel, A. von
2014-09-01
We present our most recent results on the calculation of the heavy flavor contributions to deep-inelastic scattering at 3-loop order in the large Q 2 limit, where the heavy flavor Wilson coefficients are known to factorize into light flavor Wilson coefficients and massive operator matrix elements. We describe the different techniques employed for the calculation and show the results in the case of the heavy flavor non-singlet and pure singlet contributions to the structure function F 2 (x,Q 2 ).
On the amplitude/Wilson loop duality in N=2 SCQCD
Directory of Open Access Journals (Sweden)
Marta Leoni
2015-07-01
Full Text Available We compute the four-point amplitude with external adjoint particles in N=2 SCQCD at two loops using N=1 superspace Feynman diagrams, extending the results of arXiv:1406.7283. We consider the diagrammatic difference with the corresponding process of N=4 SYM finding a non-vanishing result, which is a non-trivial function of the kinematic variables. This demonstrates that in N=2 SCQCD, even in the sector with external particles in the vector multiplet, the amplitude/Wilson loop duality is inevitably broken at two loops.
One-loop Wilson loops and the particle-interface potential in AdS/dCFT
Directory of Open Access Journals (Sweden)
Marius de Leeuw
2017-05-01
Full Text Available We initiate the calculation of quantum corrections to Wilson loops in a class of four-dimensional defect conformal field theories with vacuum expectation values based on N=4 super Yang–Mills theory. Concretely, we consider an infinite straight Wilson line, obtaining explicit results for the one-loop correction to its expectation value in the large-N limit. This allows us to extract the particle-interface potential of the theory. In a further double-scaling limit, we compare our results to those of a previous calculation in the dual string-theory set-up consisting of a D5-D3 probe-brane system with flux, and we find perfect agreement.
Wilson loops on three-manifolds and their M2-brane duals
International Nuclear Information System (INIS)
Farquet, Daniel; Sparks, James
2014-01-01
We compute the large N limit of Wilson loop expectation values for a broad class of N=2 supersymmetric gauge theories defined on a general class of background three-manifolds M 3 , diffeomorphic to S 3 . We find a simple closed formula which depends on the background geometry only through a certain supersymmetric Killing vector field. The supergravity dual of such a Wilson loop is an M2-brane wrapping the M-theory circle, together with a complex curve Σ 2 in a self-dual Einstein manifold M 4 , whose conformal boundary is M 3 . We show that the regularized action of this M2-brane also depends only on the supersymmetric Killing vector, precisely reproducing the large N field theory computation.
3-loop contributions to heavy flavor Wilson coefficients of neutral and charged current DIS
Energy Technology Data Exchange (ETDEWEB)
Hasselhuhn, Alexander
2013-11-15
In the present thesis several new contributions are made to achieve this goal. Different gauge-invariant subsets of graphs, i.e. whole color factors, are calculated, in order to break the ground for the systematic evaluation of new topologies and to develop corresponding computer algebra codes and computational algorithms to render a part of these problems. Furthermore, also some new results are obtained on the 2-loop level. The work focuses on the heavy quark corrections in the asymptotic region Q{sup 2} >> m{sup 2}, where the heavy flavor Wilson coefficients factorize into the light flavor Wilson coefficients and massive operator matrix elements. New contributions are obtained for the complete O({alpha}{sub s}{sup 3}n{sub f}T{sub F}{sup 2}) corrections to the operator matrix elements A{sub gq,Q} and A{sub gg,Q}. The computation of the Feynman integrals is performed using representations in generalized hypergeometric functions and finite sums. These sums are performed using modern symbolic summation methods implemented in the packages Sigma, Evaluate Multi Sums, and Sum Production. The results are renormalized and checked against Mellin moments. Furthermore, also the 2-loop corrections to the polarized massive OMEs {Delta}A{sub gq,Q} and {Delta}A{sub gg,Q} are calculated. Since the calculations are performed in dimensional regularization and Levi-Civita tensors are present in the diagrams, the OMEs are subject to a finite renormalization. New methods are developed to calculate genuine 3-loop topologies of ladder- and V-type, taking into account the number of heavy quark lines involved. The calculation methods involves mapping the Feynman parameterized representations onto multi-sums and using properties of Appell functions and other generalizations of hypergeometric functions. Two integrals are presented, for which the solution with summation methods remains yet an open problem. At three loops, for the first time also graphs with two distinct massive lines occur
3-loop contributions to heavy flavor Wilson coefficients of neutral and charged current DIS
International Nuclear Information System (INIS)
Hasselhuhn, Alexander
2013-11-01
In the present thesis several new contributions are made to achieve this goal. Different gauge-invariant subsets of graphs, i.e. whole color factors, are calculated, in order to break the ground for the systematic evaluation of new topologies and to develop corresponding computer algebra codes and computational algorithms to render a part of these problems. Furthermore, also some new results are obtained on the 2-loop level. The work focuses on the heavy quark corrections in the asymptotic region Q 2 >> m 2 , where the heavy flavor Wilson coefficients factorize into the light flavor Wilson coefficients and massive operator matrix elements. New contributions are obtained for the complete O(α s 3 n f T F 2 ) corrections to the operator matrix elements A gq,Q and A gg,Q . The computation of the Feynman integrals is performed using representations in generalized hypergeometric functions and finite sums. These sums are performed using modern symbolic summation methods implemented in the packages Sigma, Evaluate Multi Sums, and Sum Production. The results are renormalized and checked against Mellin moments. Furthermore, also the 2-loop corrections to the polarized massive OMEs ΔA gq,Q and ΔA gg,Q are calculated. Since the calculations are performed in dimensional regularization and Levi-Civita tensors are present in the diagrams, the OMEs are subject to a finite renormalization. New methods are developed to calculate genuine 3-loop topologies of ladder- and V-type, taking into account the number of heavy quark lines involved. The calculation methods involves mapping the Feynman parameterized representations onto multi-sums and using properties of Appell functions and other generalizations of hypergeometric functions. Two integrals are presented, for which the solution with summation methods remains yet an open problem. At three loops, for the first time also graphs with two distinct massive lines occur. A new method is presented for the calculation of such diagrams
On the large N limit, Wilson Loops, Confinement and Composite Antisymmetric Tensor Field theories
Castro, C
2004-01-01
A novel approach to evaluate the Wilson loops asociated with a $ SU ( \\infty )$ gauge theory in terms of pure string degrees of freedom is presented. It is based on the Guendelman-Nissimov-Pacheva formulation of composite antisymmetric tensor field theories of area (volume ) preserving diffeomorphisms which admit $p$-brane solutions and which provide a $new$ route to scale symmetry breaking and confinement in Yang-Mills theory. The quantum effects are discussed and we evaluate the vacuum expectation values (vev) of the Wilson loops in the large $N$ limit of the $quenched$ reduced $SU(N)$ Yang-Mills theory in terms of a path integral involving pure string degrees of freedom. The $quenched$ approximation is necessary to avoid a crumpling of the string world-sheet giving rise to very large Hausdorff dimensions as pointed out by Olesen. The approach is also consistent with the recent results based on the AdS/CFT correspondence and dual QCD models (dual Higgs model with dual Dirac strings ). More general Loop wav...
Hanada, Masanori; Miwa, Akitsugu; Nishimura, Jun; Takeuchi, Shingo
2009-05-08
In the string-gauge duality it is important to understand how the space-time geometry is encoded in gauge theory observables. We address this issue in the case of the D0-brane system at finite temperature T. Based on the duality, the temporal Wilson loop W in gauge theory is expected to contain the information of the Schwarzschild radius RSch of the dual black hole geometry as log(W)=RSch/(2pialpha'T). This translates to the power-law behavior log(W)=1.89(T/lambda 1/3)-3/5, where lambda is the 't Hooft coupling constant. We calculate the Wilson loop on the gauge theory side in the strongly coupled regime by performing Monte Carlo simulations of supersymmetric matrix quantum mechanics with 16 supercharges. The results reproduce the expected power-law behavior up to a constant shift, which is explainable as alpha' corrections on the gravity side. Our conclusion also demonstrates manifestly the fuzzball picture of black holes.
Relativistic corrections to the static energy in terms of Wilson loops at weak coupling
Energy Technology Data Exchange (ETDEWEB)
Peset, Clara [Technische Universitaet Muenchen, Physik Department T31, Garching (Germany); Pineda, Antonio [Universitat Autonoma de Barcelona, Grup de Fisica Teorica, Dept. Fisica y IFAE-BIST, Barcelona (Spain); Stahlhofen, Maximilian [Johannes Gutenberg University, PRISMA Cluster of Excellence, Institute of Physics, Mainz (Germany)
2017-10-15
We consider the O(1/m) and the spin-independent momentum-dependent O(1/m{sup 2}) quasi-static energies of heavy quarkonium (with unequal masses). They are defined nonperturbatively in terms of Wilson loops. We determine their short-distance behavior through O(α{sup 3}) and O(α{sup 2}), respectively. In particular, we calculate the ultrasoft contributions to the quasi-static energies, which requires the resummation of potential interactions. Our results can be directly compared to lattice simulations. In addition, we also compare the available lattice data with the expectations from effective string models for the long-distance behavior of the quasi-static energies. (orig.)
QCD Condensates and Holographic Wilson Loops for Asymptotically AdS Spaces
Energy Technology Data Exchange (ETDEWEB)
Quevedo, R. Carcasses [Instituto Balseiro, Centro Atomico Bariloche, 8400 San Carlos de Bariloche (Argentina); CONICET, Rivadavia 1917, 1033 Buenos Aires (Argentina); Goity, Jose L. [Hampton University, Hampton, VA 23668 (United States); Thomas Jefferson National Accelerator Facility, Newport News, VA (United States); Trinchero, Roberto C. [Instituto Balseiro, Centro Atomico Bariloche, 8400 San Carlos de Bariloche (Argentina); CONICET, Rivadavia 1917, 1033 Buenos Aires (Argentina)
2014-02-01
The minimization of the Nambu-Goto (NG) action for a surface whose contour defines a circular Wilson loop of radius a placed at a finite value of the coordinate orthogonal to the border is considered. This is done for asymptotically AdS spaces. The condensates of dimension n = 2, 4, 6, 8, and 10 are calculated in terms of the coefficients in the expansion in powers of the radius a of the on-shell subtracted NG action for small a->0. The subtraction employed is such that it presents no conflict with conformal invariance in the AdS case and need not introduce an additional infrared scale for the case of confining geometries. It is shown that the UV value of the gluon condensates is universal in the sense that it only depends on the first coefficients of the difference with the AdS case.
QCD condensates and holographic Wilson loops for asymptotically AdS spaces
Quevedo, R. Carcasses; Goity, J. L.; Trinchero, R. C.
2014-02-01
The minimization of the Nambu-Goto action for a surface whose contour defines a circular Wilson loop of radius a placed at a finite value of the coordinate orthogonal to the boundary is considered. This is done for asymptotically anti-de Sitter (AdS) spaces. The condensates of even dimension n =2 through 10 are calculated in terms of the coefficient of an in the expansion of the on-shell subtracted Nambu-Goto action for small a. The subtraction employed is such that it presents no conflict with conformal invariance in the AdS case and need not introduce an additional infrared scale for the case of confining geometries. It is shown that the UV value of the condensates is universal in the sense that they only depend on the first coefficients of the difference with the AdS case.
Wilson loop and dimensional reduction in non-commutative gauge theories
Lee, Sunggeun; Sin, Sang-Jin
2002-01-01
Using the AdS/CFT correspondence we study UV behavior of Wilson loops in various noncommutative gauge theories. We get an area law in most cases and try to identify its origin. In D3 case, we may identify the origin as the D1 dominance over the D3: as we go to the boundary of the AdS space, the effect of the flux of the D3 charge is highly suppressed, while the flux due to the D1 charge is enhanced. So near the boundary the theory is more like a theory on D1 brane than that on D3 brane. This phenomena is closely related to the dimensional reduction due to the strong magnetic field in the charged particle in the magnetic field. The linear potential is not due to the confinement by IR effect but is the analogue of Coulomb's potential in 1+1 dimension.
Energy Technology Data Exchange (ETDEWEB)
Ablinger, J.; Hasselhuhn, A.; Schneider, C. [Johannes Kepler Univ., Linz (Austria). Research Inst. for Symbolic Computation (RISC); Bluemlein, J.; Freitas, A. de [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany); Wissbrock, F. [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany); Johannes Kepler Univ., Linz (Austria). Research Inst. for Symbolic Computation (RISC); IHES, Bures-sur-Yvette (France)
2017-05-15
Starting at 3-loop order, the massive Wilson coefficients for deep-inelastic scattering and the massive operator matrix elements describing the variable flavor number scheme receive contributions of Feynman diagrams carrying quark lines with two different masses. In the case of the charm and bottom quarks, the usual decoupling of one heavy mass at a time no longer holds, since the ratio of the respective masses, η=m{sup 2}{sub c}/m{sup 2}{sub b}∝1/10, is not small enough. Therefore, the usual variable flavor number scheme (VFNS) has to be generalized. The renormalization procedure in the two-mass case is different from the single mass case derived earlier (I. Bierenbaum, J: Bluemlein, S. Klein, 2009). We present the moments N=2,4 and 6 for all contributing operator matrix elements, expanding in the ratio η. We calculate the analytic results for general values of the Mellin variable N in the flavor non-singlet case, as well as for transversity and the matrix element A{sup (3)}{sub gq}. We also calculate the two-mass scalar integrals of all topologies contributing to the gluonic operator matrix element A{sub gg}. As it turns out, the expansion in η is usually inapplicable for general values of N. We therefore derive the result for general values of the mass ratio. From the single pole terms we derive, now in a two-mass calculation, the corresponding contributions to the 3-loop anomalous dimensions. We introduce a new general class of iterated integrals and study their relations and present special values. The corresponding functions are implemented in computer-algebraic form.
Minimal area surfaces in AdS n+1 and Wilson loops
He, Yifei; Huang, Changyu; Kruczenski, Martin
2018-02-01
The AdS/CFT correspondence relates the expectation value of Wilson loops in N = 4 SYM to the area of minimal surfaces in AdS 5. In this paper we consider minimal area surfaces in generic Euclidean AdS n+1 using the Pohlmeyer reduction in a similar way as we did previously in Euclidean AdS 3. As in that case, the main obstacle is to find the correct parameterization of the curve in terms of a conformal parameter. Once that is done, the boundary conditions for the Pohlmeyer fields are obtained in terms of conformal invariants of the curve. After solving the Pohlmeyer equations, the area can be expressed as a boundary integral involving a generalization of the conformal arc-length, curvature and torsion of the curve. Furthermore, one can introduce the λ-deformation symmetry of the contours by a simple change in the conformal invariants. This determines the λ-deformed contours in terms of the solution of a boundary linear problem. In fact the condition that all λ deformed contours are periodic can be used as an alternative to solving the Pohlmeyer equations and is equivalent to imposing the vanishing of an infinite set of conserved charges derived from integrability.
Wilson loops from multicentre and rotating branes, mass gaps and phase structure in gauge theories
Brandhuber, A.
1999-01-01
Within the AdS/CFT correspondence we use multicentre D3-brane metrics to investigate Wilson loops and compute the associated heavy quark-antiquark potentials for the strongly coupled SU(N) super-Yang-Mills gauge theory, when the gauge symmetry is broken by the expectation values of the scalar fields. For the case of a uniform distribution of D3-branes over a disc, we find that there exists a maximum separation beyond which there is no force between the quark and the antiquark, i.e. the screening is complete. We associate this phenomenon with the possible existence of a mass gap in the strongly coupled gauge theory. In the finite-temperature case, when the corresponding supergravity solution is a rotating D3-brane solution, there is a class of potentials interpolating between a Coulombic and a confining behaviour. However, above a certain critical value of the mass parameter, the potentials exhibit a behaviour characteristic of statistical systems undergoing phase transitions. The physical path preserves the c...
Matsudo, Ryutaro; Kondo, Kei-Ichi; Shibata, Akihiro
2018-03-01
We examine how the average of double-winding Wilson loops depends on the number of color N in the SU(N) Yang-Mills theory. In the case where the two loops C1 and C2 are identical, we derive the exact operator relation which relates the doublewinding Wilson loop operator in the fundamental representation to that in the higher dimensional representations depending on N. By taking the average of the relation, we find that the difference-of-areas law for the area law falloff recently claimed for N = 2 is excluded for N ⩾ 3, provided that the string tension obeys the Casimir scaling for the higher representations. In the case where the two loops are distinct, we argue that the area law follows a novel law (N - 3)A1/(N - 1) + A2 with A1 and A2(A1 law when (N ⩾ 3). Indeed, this behavior can be confirmed in the two-dimensional SU(N) Yang-Mills theory exactly.
Wilson loops in 3-dimensional N = 6 supersymmetric Chern-Simons theory and their string theory duals
International Nuclear Information System (INIS)
Drukker, Nadav; Plefka, Jan; Young, Donovan
2008-01-01
We study Wilson loops in the three-dimensional N = 6 supersymmetric Chern-Simons theory recently constructed by Aharony, Bergman, Jafferis and Maldacena, that is conjectured to be dual to type IIA string theory on AdS 4 x CP 3 . We construct loop operators in the Chern-Simons theory which preserve 1/6 of the supercharges and calculate their expectation value up to 2-loop order at weak coupling. The expectation value at strong coupling is found by constructing the string theory duals of these operators. For low dimensional representations these are fundamental strings, for high dimensional representations these are D2-branes and D6-branes. In support of this identification we demonstrate that these string theory solutions match the symmetries, charges and the preserved supersymmetries of their Chern-Simons theory counterparts.
Wilson-Polyakov loops for critical strings and superstrings at finite temperature
International Nuclear Information System (INIS)
Green, M.B.
1992-01-01
An open string with end-points fixed at spatial separation L is a string theory analogue of the static quark-antiquark system in quenched QCD. Folowing a review of the quantum mechanics of this system in critical bosonic string theory the partition function at finite β (the inverse temperature) for fixed end-point open strings is discussed. This is related by a conformal transformation ('world-sheet duality') to the correlation function of two closed strings fixed at distinct spatial points (a string theory analogue of two Wilson-Polyakov loops). Temperature duality (β → β' = 4π 2 /β) relates this correlation function, in turn, to the finite-temperature Green function for a closed strong propagating between initial and final states that are at distinct (euclidean) space-time points. In addition, spatial duality relates the fixed end-point open string to the familiar open string with free end-points. A generalization to fixed end-points superstrings is suggested, in which the superalgebra may be viewed as the spatial dual of the usual open-string superalgebra. At zero temperature world-sheet duality relates the partition function of supersymmetric fixed end-point open strings to the correlation function of point-like closed-string states. These couple to combinations of the scalar and pseudoscalar states of a type-2b superstring superfield. At finite temperature supersymmetry is broken and this correlation function involves the propagation of non-supersymmetric states with non-zero winding numbers (which formally include a tachyon at temperatures above the Hagedorn transition). Temperature duality again relates the partition function to the finite-temperature Green function describing the propagator for point-like closed-string states of the dual theory, in which supersymmetry is broken. The singularity that arises in the critical bosonic theory as L is reduced below L = 2 π√α' is absent in the superstring and the static potential is well defined for all
International Nuclear Information System (INIS)
Brambilla, M.; Di Renzo, F.
2013-01-01
Numerical Stochastic Perturbation Theory was able to get three- (and even four-) loop results for finite Lattice QCD renormalization constants. More recently, a conceptual and technical framework has been devised to tame finite size effects, which had been reported to be significant for (logarithmically) divergent renormalization constants. In this work we present three-loop results for fermion bilinears in the Lattice QCD regularization defined by tree-level Symanzik improved gauge action and n f =2 Wilson fermions. We discuss both finite and divergent renormalization constants in the RI'-MOM scheme. Since renormalization conditions are defined in the chiral limit, our results also apply to Twisted Mass QCD, for which non-perturbative computations of the same quantities are available. We emphasize the importance of carefully accounting for both finite lattice space and finite volume effects. In our opinion the latter have in general not attracted the attention they would deserve. (orig.)
Directory of Open Access Journals (Sweden)
Matsudo Ryutaro
2018-01-01
Full Text Available We examine how the average of double-winding Wilson loops depends on the number of color N in the SU(N Yang-Mills theory. In the case where the two loops C1 and C2 are identical, we derive the exact operator relation which relates the doublewinding Wilson loop operator in the fundamental representation to that in the higher dimensional representations depending on N. By taking the average of the relation, we find that the difference-of-areas law for the area law falloff recently claimed for N = 2 is excluded for N ⩾ 3, provided that the string tension obeys the Casimir scaling for the higher representations. In the case where the two loops are distinct, we argue that the area law follows a novel law (N − 3A1/(N − 1 + A2 with A1 and A2(A1 < A2 being the minimal areas spanned respectively by the loops C1 and C2, which is neither sum-ofareas (A1 + A2 nor difference-of-areas (A2 − A1 law when (N ⩾ 3. Indeed, this behavior can be confirmed in the two-dimensional SU(N Yang-Mills theory exactly.
Wilson disease is a rare inherited disorder that prevents your body from getting rid of extra copper. You need ... copper into bile, a digestive fluid. With Wilson disease, the copper builds up in your liver, and ...
Energy Technology Data Exchange (ETDEWEB)
Gukov, Sergei [Walter Burke Institute for Theoretical Physics, California Institute of Technology,1200 E California Blvd, Pasadena, CA 91125 (United States); Max-Planck-Institut für Mathematik,Vivatsgasse 7, D-53111 Bonn (Germany); Nawata, Satoshi [Walter Burke Institute for Theoretical Physics, California Institute of Technology,1200 E California Blvd, Pasadena, CA 91125 (United States); Centre for Quantum Geometry of Moduli Spaces, University of Aarhus,Nordre Ringgade 1, DK-8000 (Denmark); Saberi, Ingmar [Walter Burke Institute for Theoretical Physics, California Institute of Technology,1200 E California Blvd, Pasadena, CA 91125 (United States); Stošić, Marko [CAMGSD, Departamento de Matemática, Instituto Superior Técnico,Av. Rovisco Pais, 1049-001 Lisbon (Portugal); Mathematical Institute SANU,Knez Mihajlova 36, 11000 Belgrade (Serbia); Sułkowski, Piotr [Walter Burke Institute for Theoretical Physics, California Institute of Technology,1200 E California Blvd, Pasadena, CA 91125 (United States); Faculty of Physics, University of Warsaw,ul. Pasteura 5, 02-093 Warsaw (Poland)
2016-03-02
This paper provides both a detailed study of color-dependence of link homologies, as realized in physics as certain spaces of BPS states, and a broad study of the behavior of BPS states in general. We consider how the spectrum of BPS states varies as continuous parameters of a theory are perturbed. This question can be posed in a wide variety of physical contexts, and we answer it by proposing that the relationship between unperturbed and perturbed BPS spectra is described by a spectral sequence. These general considerations unify previous applications of spectral sequence techniques to physics, and explain from a physical standpoint the appearance of many spectral sequences relating various link homology theories to one another. We also study structural properties of colored HOMFLY homology for links and evaluate Poincaré polynomials in numerous examples. Among these structural properties is a novel “sliding” property, which can be explained by using (refined) modular S-matrix. This leads to the identification of modular transformations in Chern-Simons theory and 3d N=2 theory via the 3d/3d correspondence. Lastly, we introduce the notion of associated varieties as classical limits of recursion relations of colored superpolynomials of links, and study their properties.
... tremor may include anticholinergics, tizanidine, baclofen, levodopa, or clonazepam. × Treatment WD requires lifelong treatment, generally using drugs ... tremor may include anticholinergics, tizanidine, baclofen, levodopa, or clonazepam. View Full Treatment Information Definition Wilson disease (WD) ...
Energy Technology Data Exchange (ETDEWEB)
Gudnason, Sven Bjarke [Institute of Modern Physics, Chinese Academy of Sciences,Lanzhou 730000 (China); Nitta, Muneto [Department of Physics, and Research and Education Center for Natural Sciences, Keio University,Hiyoshi 4-1-1, Yokohama, Kanagawa 223-8521 (Japan); Sawado, Nobuyuki [Department of Physics, Tokyo University of Science,Noda, Chiba 278-8510 (Japan)
2015-12-02
The BPS Skyrme model has many exact analytic solutions in flat space. We generalize the model to a curved space or spacetime and find that the solutions can only be BPS for a constant time-time component of the metric tensor. We find exact solutions on the curved spaces: a 3-sphere and a 3-hyperboloid; and we further find an analytic gravitating Skyrmion on the 3-sphere. For the case of a nontrivial time-time component of the metric, we suggest a potential for which we find analytic solutions on anti-de Sitter and de Sitter spacetimes in the limit of no gravitational backreaction. We take the gravitational coupling into account in numerical solutions and show that they are well approximated by the analytic solutions for weak gravitational coupling.
Generalized BPS magnetic monopoles
Casana, R.; Ferreira, M. M., Jr.; da Hora, E.
2012-10-01
We show the existence of Bogomol’nyi-Prasad-Sommerfield (BPS) magnetic monopoles in a generalized Yang-Mills-Higgs model which is controlled by two positive functions, g(ϕaϕa) and f(ϕaϕa). This effective model, in principle, would describe the dynamics of the nonabelian fields in a chromoelectric media. We check the consistency of our generalized construction by analyzing an explicit case ruled by a parameter β. We also use the well-known spherically symmetric Ansatz to attain the corresponding self-dual equations describing the topological solutions. The overall conclusion is that the new solutions behave around the canonical one, with smaller or greater characteristic length depending on the values of β.
Wilson lines in quantum field theory
Cherednikov, Igor O; Veken, Frederik F van der
2014-01-01
The objective of this book is to get the reader acquainted with theoretical and mathematical foundations of the concept of Wilson loops in the context of modern quantum field theory. It teaches how to perform independently with some elementary calculations on Wilson lines, and shows the recent development of the subject in different important areas of research.
BPS Skyrmions as neutron stars
Directory of Open Access Journals (Sweden)
C. Adam
2015-03-01
Full Text Available The BPS Skyrme model has been demonstrated already to provide a physically intriguing and quantitatively reliable description of nuclear matter. Indeed, the model has both the symmetries and the energy–momentum tensor of a perfect fluid, and thus represents a field theoretic realization of the “liquid droplet” model of nuclear matter. In addition, the classical soliton solutions together with some obvious corrections (spin–isospin quantization, Coulomb energy, proton–neutron mass difference provide an accurate modeling of nuclear binding energies for heavier nuclei. These results lead to the rather natural proposal to try to describe also neutron stars by the BPS Skyrme model coupled to gravity. We find that the resulting self-gravitating BPS Skyrmions provide excellent results as well as some new perspectives for the description of bulk properties of neutron stars when the parameter values of the model are extracted from nuclear physics. Specifically, the maximum possible mass of a neutron star before black-hole formation sets in is a few solar masses, the precise value of which depends on the precise values of the model parameters, and the resulting neutron star radius is of the order of 10 km.
BPS submodels of the Skyrme model
Energy Technology Data Exchange (ETDEWEB)
Adam, C., E-mail: adam@fpaxp1.usc.es [Departamento de Física de Partículas, Universidad de Santiago de Compostela and Instituto Galego de Física de Altas Enerxias (IGFAE), E-15782 Santiago de Compostela (Spain); Sanchez-Guillen, J. [Departamento de Física de Partículas, Universidad de Santiago de Compostela and Instituto Galego de Física de Altas Enerxias (IGFAE), E-15782 Santiago de Compostela (Spain); Wereszczynski, A. [Institute of Physics, Jagiellonian University, Lojasiewicza 11, Kraków (Poland)
2017-06-10
We show that the standard Skyrme model without pion mass term can be expressed as a sum of two BPS submodels, i.e., of two models whose static field equations, independently, can be reduced to first order equations. Further, these first order (BPS) equations have nontrivial solutions, at least locally. These two submodels, however, cannot have common solutions. Our findings also shed some light on the rational map approximation. Finally, we consider certain generalisations of the BPS submodels.
DEFF Research Database (Denmark)
Bownik, Marcin; Jakobsen, Mads Sielemann; Lemvig, Jakob
2017-01-01
A Wilson system is a collection of finite linear combinations of time frequency shifts of a square integrable function. In this paper we give an account of the construction of bimodular Wilson bases in higher dimensions from Gabor frames of redundancy two.......A Wilson system is a collection of finite linear combinations of time frequency shifts of a square integrable function. In this paper we give an account of the construction of bimodular Wilson bases in higher dimensions from Gabor frames of redundancy two....
Monte Carlo calculation with unquenched Wilson-Fermions
International Nuclear Information System (INIS)
Montvay, I.
1984-01-01
A Monte Carlo updating procedure taking into account the virtual quark loops is described. It is based on high order hopping parameter expansion of the quark determinant for Wilson-fermions. In a first test run Wilson-loop expectation values are measured on 6 4 lattice at β=5.70 using 16sup(th) order hopping parameter expansion for the quark determinant. (orig.)
Perturbative Renormalization of Wilson line operators
Constantinou, Martha; Panagopoulos, Haralambos
2018-03-01
We present results for the renormalization of gauge invariant nonlocal fermion operators which contain a Wilson line, to one loop level in lattice perturbation theory. Our calculations have been performed for Wilson/clover fermions and a wide class of Symanzik improved gluon actions. The extended nature of such `long-link' operators results in a nontrivial renormalization, including contributions which diverge linearly as well as logarithmically with the lattice spacing, along with additional finite factors. We present nonperturbative prescriptions to extract the linearly divergent contributions.
Light-cone superspace BPS theory
Hearin, Patrick
2011-05-01
The BPS bound is formulated in light-cone superspace for the N=4 super-Yang-Mills theory. As a consequence of the superalgebra all momenta are shown to be expressed as a quadratic form in the relevant supertransformations, and these forms are used to derive the light-cone superspace BPS equations. Finally, the superfield expressions are expanded out to component form, and the Wu-Yang monopole boosted to the infinite momentum frame is shown to be a solution.
Wilson's Disease Association International
... News & Announcements Wilson's Warriors Events Back The Big WOW 2017 Annual Conference WDA Publications Back Downloads Corporate Sponsorship Forms Membership Forms Resources The Big WOW Newsletters News Copper Connection Newsletter Resources Centers of ...
International Nuclear Information System (INIS)
Anon.
1994-01-01
On March 4, an international symposium and tribute was held at Fermilab in honour of the Laboratory's founding director Robert Rathbun Wilson on the occasion of his 80th birthday. The symposium - 'Celebrating an Era of Courage and Creativity' - featured talks and reflections by many of Wilson's colleagues and friends including Fermilab Director John Peoples and Director Emeritus Leon Lederman
Interacting open Wilson lines from noncommutative field theories
International Nuclear Information System (INIS)
Kiem, Youngjai; Lee, Sangmin; Rey, Soo-Jong; Sato, Haru-Tada
2002-01-01
In noncommutative field theories, it is known that the one-loop effective action describes the propagation of noninteracting open Wilson lines, obeying the flying dipole's relation. We show that the two-loop effective action describes the cubic interaction among 'closed string' states created by open Wilson line operators. Taking d-dimensional λ[Φ 3 ] * theory as the simplest setup, we compute the nonplanar contribution at a low-energy and large noncommutativity limit. We find that the contribution is expressible in a remarkably simple cubic interaction involving scalar open Wilson lines only and nothing else. We show that the interaction is purely geometrical and noncommutative in nature, depending only on the size of each open Wilson line
Classical and quantum aspects of BPS black holes in N=2,D=4 heterotic string compactifications
International Nuclear Information System (INIS)
Rey, S.-J.
1997-01-01
We study classical and quantum aspects of D=4, N=2 BPS black holes for T 2 compactification of D=6, N=1 heterotic string vacua. We extend dynamical relaxation phenomena of moduli fields to a background consisting of a BPS soliton or a black hole and provide a simpler but more general derivation of the Ferrara-Kallosh extremized black hole mass and entropy. We study quantum effects to the BPS black hole mass spectra and to their dynamical relaxation. We show that, despite non-renormalizability of string effective supergravity, the quantum effect modifies BPS mass spectra only through coupling constant and moduli field renormalizations. Based on target-space duality, we establish a perturbative non-renormalization theorem and obtain the exact BPS black hole mass and entropy in terms of the renormalized string loop-counting parameter and renormalized moduli fields. We show that a similar conclusion holds, in the large T 2 limit, for leading non-perturbative correction. We finally discuss implications to type-I and type-IIA Calabi-Yau black holes. (orig.)
BPS Lorentz-violating vortex solutions
International Nuclear Information System (INIS)
Casana, Rodolfo; Ferreira Junior, Manoel M.; Hora, E. da
2011-01-01
In this work, we deal with the construction of static Bogomol'nyi-Prasad-Sommerfield (BPS) rotationally symmetric configurations on the dimensional CPT-even Lorentz-breaking photonic sector of the Standard Model Extension (SME). The main objective of this presentation is to show the possibility of obtaining such BPS solutions, even in the presence of a Lorentz-violating background. A secondary objective is to analyze the effects of this background on such topologically non-trivial BPS configurations. In order to obtain these results, we deal with some specific components of Lorentz-violating field, handling with the static Euler-Lagrange equation of motion to gauge field, from which we fix temporal gauge (absence of electric field) as a proper gauge choice. Also, considering this equation, we consistently determine an interesting configuration (discarding non-interesting ones) to the Lorentz-breaking sector. Using this configuration and the standard rotationally symmetric vortex Ansatz (which describes the behaviors of Higgs and gauge fields via two profile functions, g(r) and a(r), respectively), we construct a rotationally symmetric expression to the energy density of the system. To obtain BPS solutions, we rewrite this expression in order to have static vortex solutions satisfying a set of first order differential equations (BPS ones). The existence of such solutions is strongly constrained by a relation between some parameters of the model, including the Lorentz-breaking one. Naturally, we show that the total energy of these BPS solutions is proportional to their magnetic flux, which is quantized according to their winding number. Using suitable boundary conditions (near the origin and asymptotically), we numerically integrate the BPS equations (by means of the shooting method). By this way, we obtain solutions for some physical quantities (Higgs field, magnetic field and energy density) for several values of the Lorentz-violating parameters. From these
African Journals Online (AJOL)
Ebot, Wilson Atem. Vol 8-9, No 1 (1995) - Articles Language and socio-cultural change in Ejagham Abstract PDF. ISSN: 1016-0728. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and Conditions of Use · Contact AJOL ...
DEFF Research Database (Denmark)
Engenheiro, E; Møller, R S; Pinto, M
2008-01-01
Mowat-Wilson syndrome (MWS) is an autosomal dominant developmental disorder with mental retardation and variable multiple congenital abnormalities due to mutations of the ZEB2 (ZFHX1B) gene at 2q22. MWS was first described in 1998 and the causative gene was delineated in 2001. Since then, 115 dif...
Exact BPS bound for noncommutative baby Skyrmions
Energy Technology Data Exchange (ETDEWEB)
Domrin, Andrei, E-mail: domrin@mi.ras.ru [Department of Mathematics and Mechanics, Moscow State University, Leninskie gory, 119992, GSP-2, Moscow (Russian Federation); Lechtenfeld, Olaf, E-mail: lechtenf@itp.uni-hannover.de [Institut für Theoretische Physik and Riemann Center for Geometry and Physics, Leibniz Universität Hannover, Appelstraße 2, 30167 Hannover (Germany); Linares, Román, E-mail: lirr@xanum.uam.mx [Departamento de Física, Universidad Autónoma Metropolitana Iztapalapa, San Rafael Atlixco 186, C.P. 09340, México D.F. (Mexico); Maceda, Marco, E-mail: mmac@xanum.uam.mx [Departamento de Física, Universidad Autónoma Metropolitana Iztapalapa, San Rafael Atlixco 186, C.P. 09340, México D.F. (Mexico)
2013-11-25
The noncommutative baby Skyrme model is a Moyal deformation of the two-dimensional sigma model plus a Skyrme term, with a group-valued or Grassmannian target. Exact abelian solitonic solutions have been identified analytically in this model, with a singular commutative limit. Inside any given Grassmannian, we establish a BPS bound for the energy functional, which is saturated by these baby Skyrmions. This asserts their stability for unit charge, as we also test in second-order perturbation theory.
Electrified BPS giants: BPS configurations on giant gravitons with static electric field
International Nuclear Information System (INIS)
Ali-Akbari, Mohammad; Sheikh-Jabbari, Mohammad Mahdi
2007-01-01
We consider D3-brane action in the maximally supersymmetric type IIB plane-wave background. Upon fixing the light-cone gauge, we obtain the light-cone Hamiltonian which is manifestly supersymmetric. The 1/2 BPS solutions of this theory (solutions which preserve 16 supercharges) are either of the form of spherical three branes, the giant gravitons, or zero size point like branes. We then construct specific classes of 1/4 BPS solutions of this theory in which static electric field on the brane is turned on. These solutions are deformations about either of the two 1/2 BPS solutions. In particular, we study in some detail 1/4 BPS configurations with electric dipole on the three sphere giant, i.e. BIons on the giant gravitons, which we hence call BIGGons. We also study BPS configurations corresponding to turning on a background uniform constant electric field. As a result of this background electric field the three sphere giant is deformed to squashed sphere, while the zero size point like branes turn into circular or straight fundamental strings in the plane-wave background, with their tension equal to the background electric field
Energy Technology Data Exchange (ETDEWEB)
Green, Daniel; /SLAC /Stanford U., Dept. Phys.
2008-04-29
Gravitational theories do not admit gauge invariant local operators. We study the limits under which there exists a quasi-local description for a class of non-local gravitational observables where a sum over worldlines plays the role of the Wilson line for gauge theory observables. We study non-local corrections to the local description and circumstances where these corrections become large. We find that these operators are quasi-local in at space and AdS, but fail to be quasi-local in de Sitter space.
Robert Wilson og muscial formatet
DEFF Research Database (Denmark)
Eigtved, Michael
2002-01-01
Artiklen undersøger hvordan Robert Wilson og Tom Waits' forestilling The Black Rider (1995) forholder sig til musicalkonventionerne......Artiklen undersøger hvordan Robert Wilson og Tom Waits' forestilling The Black Rider (1995) forholder sig til musicalkonventionerne...
Genetics Home Reference: Wilson disease
... the liver, brain, and eyes. The signs and symptoms of Wilson disease usually first appear between the ages of 6 ... adulthood and commonly occur in young adults with Wilson disease . Signs and symptoms of these problems can include clumsiness, tremors, difficulty ...
BPS sectors of the Skyrme model and their non-BPS extensions
Adam, C.; Foster, D.; Krusch, S.; Wereszczynski, A.
2018-02-01
Two recently found coupled Bogomol'nyi-Prasad-Sommerfield (BPS) submodels of the Skyrme model are further analyzed. First, we provide a geometrical formulation of the submodels in terms of the eigenvalues of the strain tensor. Second, we study their thermodynamical properties and show that the mean-field equations of state coincide at high pressure and read p =ρ ¯/3 . We also provide evidence that matter described by the first BPS submodel has some similarity with a Bose-Einstein condensate. Moreover, we show that extending the second submodel to a non-BPS model by including certain additional terms of the full Skyrme model does not spoil the respective ansatz, leading to an ordinary differential equation for the profile of the Skymion, for any value of the topological charge. This allows for an almost analytical description of the properties of Skyrmions in this model. In particular, we analytically study the breaking and restoration of the BPS property. Finally, we provide an explanation of the success of the rational map ansatz.
[Jacqueline Wilson. Tracy Beakeri sari] / Krista Kivisalu
Kivisalu, Krista, 1968-
2016-01-01
Tutvustus: Wilson, Jacqueline. Tracy Beakeri lugu. [Tallinn] : Pegasus, 2015 ; Wilson, Jacqueline. Pühadeüllatus. [Tallinn] : Pegasus, c2015 ; Wilson, Jacqueline. Julgusmäng. [Tallinn] : Pegasus, c2015
Black Holes in Supergravity: the non-BPS Branch
Gimon, Eric G; Simon, Joan; PH-TH
2008-01-01
We construct extremal, spherically symmetric black hole solutions to 4D supergravity with charge assignments that preclude BPS-saturation. In particular, we determine the ground state energy as a function of charges and moduli. We find that the mass of the non-BPS black hole remains that of a marginal bound state of four basic constituents throughout the entire moduli space and that there is always a non-zero gap above the BPS bound.
Black holes in supergravity: the non-BPS branch
Energy Technology Data Exchange (ETDEWEB)
Gimon, Eric; Gimon, Eric G.; Larsen, Finn; Simon, Joan
2007-10-25
We construct extremal, spherically symmetric black hole solutions to 4D supergravity with charge assignments that preclude BPS-saturation. In particular, we determine the ground state energy as a function of charges and moduli. We find that the mass of the non-BPS black hole remains that of a marginal bound state of four basic constituents throughout the entire moduli space and that there is always a non-zero gap above the BPS bound.
1/4 BPS States and Non-Perturbative Couplings in N=4 String Theories
Lerche, W.
1999-01-01
We compute certain 2K+4-point one-loop couplings in the type IIA string compactified on K3 x T^2, which are related a topological index on this manifold. Their special feature is that they are sensitive to only short and intermediate BPS multiplets. The couplings derive from underlying prepotentials of the form G(T,U)=d^{2K}V ln[chi10(T,U,V)], where chi10(T,U,V) is the helicity partition function of 1/4 BPS states. In the dual heterotic string on T^6, the amplitudes describe non-perturbative gravitational corrections due to bound states of fivebrane instantons with heterotic world-sheet instantons. We argue, as a consequence, that our results give information about instanton configurations in six dimensional Sp(2k) gauge theories on T^6.
Energy Technology Data Exchange (ETDEWEB)
Sati, Hisham [University of Pittsburgh,Pittsburgh, PA, 15260 (United States); Mathematics Program, Division of Science and Mathematics, New York University Abu Dhabi,Saadiyat Island, Abu Dhabi (United Arab Emirates); Schreiber, Urs [Mathematics Institute of the Academy,Žitna 25, Praha 1, 115 67 (Czech Republic)
2017-03-16
We uncover higher algebraic structures on Noether currents and BPS charges. It is known that equivalence classes of conserved currents form a Lie algebra. We show that at least for target space symmetries of higher parameterized WZW-type sigma-models this naturally lifts to a Lie (p+1)-algebra structure on the Noether currents themselves. Applied to the Green-Schwarz-type action functionals for super p-brane sigma-models this yields super Lie (p+1)-algebra refinements of the traditional BPS brane charge extensions of supersymmetry algebras. We discuss this in the generality of higher differential geometry, where it applies also to branes with (higher) gauge fields on their worldvolume. Applied to the M5-brane sigma-model we recover and properly globalize the M-theory super Lie algebra extension of 11-dimensional superisometries by 2-brane and 5-brane charges. Passing beyond the infinitesimal Lie theory we find cohomological corrections to these charges in higher analogy to the familiar corrections for D-brane charges as they are lifted from ordinary cohomology to twisted K-theory. This supports the proposal that M-brane charges live in a twisted cohomology theory.
Wilson Lines and Webs in Higher-Order QCD
White, Chris D.
2018-03-01
Wilson lines have a number of uses in non-abelian gauge theories. A topical example in QCD is the description of radiation in the soft or collinear limit, which must often be resummed to all orders in perturbation theory. Correlators involving a pair of Wilson lines are known to exponentiate in terms of special Feynman diagrams called "webs". I will show how this language can be extended to an arbitrary number of Wilson lines, which introduces novel new combinatoric structures (web mixing matrices) of interest in their own right. I will also summarise recent results obtained from applying this formalism at three-loop order, before concluding with a list of open problems.
Directory of Open Access Journals (Sweden)
Esra Tuğ
2007-01-01
Full Text Available Wilson Disease (WD is an autosomal recessive hereditary disease of human copper metabolism, which causes hepatic and neuropsychiatric diseases. Estimated prevalence is 1: 30.000. In WD, ATP7B gene located on chromosome 13 (13q14.3-q21.1, coding the protein for hepatic copper transport and, having an important role in copper metabolism has been affected. Clinical findings in WD are complex and, neurological symptoms such as tremor, disartria and psychiatric disorders, acute liver deficiency, chronic hepatit or cirrhosis may develop. For the last year, 27 years old female patient observed in other medical centre owing to benign positional vertigo applied to our department. Her sister and brother have been diagnosed as WD. No peripheral syptoms of hepatic disease or hepatosplenomegaly existed in our patient. Neurological examination was normal to except for positional tremor. Because our patient had rare clinical features for WD and bad prognosis, presented by us to emphasize necessity of the researched of the most frequent mutations seen in Turkiye.
Superconformal index, BPS monodromy and chiral algebras
Cecotti, Sergio; Song, Jaewon; Vafa, Cumrun; Yan, Wenbin
2017-11-01
We show that specializations of the 4d N=2 superconformal index labeled by an integer N is given by Tr ℳ N where ℳ is the Kontsevich-Soibelman monodromy operator for BPS states on the Coulomb branch. We provide evidence that the states enumerated by these limits of the index lead to a family of 2d chiral algebras A_N . This generalizes the recent results for the N = -1 case which corresponds to the Schur limit of the superconformal index. We show that this specialization of the index leads to the same integrand as that of the elliptic genus of compactification of the superconformal theory on S 2 × T 2 where we turn on 1/2N units of U(1) r flux on S 2.
How Is Wilson Disease Inherited?
... News & Announcements Wilson's Warriors Events Back The Big WOW 2018 Annual Conference WDA Publications Back Downloads Corporate Sponsorship Forms Membership Forms Resources The Big WOW Newsletters News Copper Connection Newsletter Resources Centers of ...
How Is Wilson Disease Diagnosed?
... News & Announcements Wilson's Warriors Events Back The Big WOW 2018 Annual Conference WDA Publications Back Downloads Corporate Sponsorship Forms Membership Forms Resources The Big WOW Newsletters News Copper Connection Newsletter Resources Centers of ...
BPS counting for knots and combinatorics on words
Energy Technology Data Exchange (ETDEWEB)
Kucharski, Piotr [Faculty of Physics, University of Warsaw,ul. Pasteura 5, 02-093 Warsaw (Poland); Sułkowski, Piotr [Faculty of Physics, University of Warsaw,ul. Pasteura 5, 02-093 Warsaw (Poland); Walter Burke Institute for Theoretical Physics, California Institute of Technology,Pasadena, CA 91125 (United States)
2016-11-21
We discuss relations between quantum BPS invariants defined in terms of a product decomposition of certain series, and difference equations (quantum A-polynomials) that annihilate such series. We construct combinatorial models whose structure is encoded in the form of such difference equations, and whose generating functions (Hilbert-Poincaré series) are solutions to those equations and reproduce generating series that encode BPS invariants. Furthermore, BPS invariants in question are expressed in terms of Lyndon words in an appropriate language, thereby relating counting of BPS states to the branch of mathematics referred to as combinatorics on words. We illustrate these results in the framework of colored extremal knot polynomials: among others we determine dual quantum extremal A-polynomials for various knots, present associated combinatorial models, find corresponding BPS invariants (extremal Labastida-Mariño-Ooguri-Vafa invariants) and discuss their integrality.
On super form factors of half-BPS operators in =4 super Yang-Mills
Penante, Brenda; Spence, Bill; Travaglini, Gabriele; Wen, Congkao
2014-04-01
We compute form factors of half-BPS operators in = 4 super Yang-Mills dual to massive Kaluza-Klein modes in supergravity. These are appropriate supersymmetrisations of the scalar operators Tr ( ϕ k ) for any k, which for k = 2 give the chiral part of the stress-tensor multiplet operator. Using harmonic superspace, we derive simple Ward identities for these form factors, which we then compute perturbatively at tree level and one loop. We propose a novel on-shell recursion relation which links form factors with different numbers of fields. Using this, we conjecture a general formula for the n-point MHV form factors of for arbitrary k and n. Finally, we use supersymmetric generalised unitarity to derive compact expressions for all one-loop MHV form factors of in terms of one-loop triangles and finite two-mass easy box functions.
Investigational drugs for bladder pain syndrome (BPS) / interstitial cystitis (IC).
Chuang, Yao-Chi; Chermansky, Christopher; Kashyap, Mahendra; Tyagi, Pradeep
2016-01-01
Bladder pain syndrome (BPS)/interstitial cystitis (IC) is associated with sensory lower urinary tract symptoms. Unfortunately, many of the existing oral treatments are ineffective in most patients of BPS/IC, which is the motivation for developing new drugs and therapeutic approaches. This review covers the latest drugs that have been investigated in BPS/IC patients. Intravesical treatments offer the opportunity to directly target the painful bladder with less systemic side effects. In this review, the authors analyze the existing literature supporting the treatment of BPS/IC with conventional drugs including heparin, hyaluronic acid, chondroitin sulfate, and dimethylsulfoxide (DMSO). Furthermore, investigational drugs such as tanezumab and adalimumab, capable of sequestering nerve growth factor (NGF), and Tumor necrosis factor-α (TNF- α) are discussed. Investigational treatments such as liposomes, botulinum toxin (BTX), liposomal BTX, PD-0299685 (a Ca(2+) channel ɑ2δ ligand), continuous intravesical lidocaine, and AQX-1125 (a novel SHIP1 activating compound) are also covered. New investigational drugs offer promising improvements in clinical outcomes for BPS/IC patients; however, BPS/IC is a chronic pain disorder that is very vulnerable to a strong placebo effect. In addition, BPS/IC is a heterogeneous disorder that can be classified into several phenotypes. Since different phenotypes of BPS/IC respond differently to systemic and intravesical treatments, the authors believe that new drugs developed for BPS/IC are more likely to meet their predetermined clinical endpoints if the inclusion/exclusion criterion is tailored to specific phenotype of BPS/IC patients.
Aggarwal, Annu; Bhatt, Mohit
2013-01-01
Wilson disease (WD) is an inherited disorder of chronic copper toxicosis characterized by excessive copper deposition in the body, primarily in the liver and the brain. It is a progressive disease and fatal if untreated. Excessive copper accumulation results from the inability of liver to excrete copper in bile. Copper is an essential trace metal and has a crucial role in many metabolic processes. Almost all of the body copper is protein bound. In WD, the slow but relentless copper accumulation overwhelms the copper chaperones (copper-binding proteins), resulting in high levels of free copper and copper-induced tissue injury. Liver is the central organ for copper metabolism, and copper is initially accumulated in the liver but over time spills to other tissues. WD has protean clinical manifestations mainly attributable to liver, brain, and osseomuscular impairment. Diagnosis of WD is challenging and based on combination of clinical features and laboratory tests. Identification of various high-frequency mutations identified in different population studies across the world has revived interest in developing DNA chips for rapid genetic diagnosis of WD. All symptomatic and all presymptomatic patients require lifelong decoppering with careful clinical tracking. Decoppering ensures that presymptomatic individuals remain symptom free. With judicious decoppering, given time, even patients with severe neurological disability improve and can return to normal life and resume school or work at par with their peers. Treatment regimens and tracking patients using the WD-specific Global Assessment Scale for WD (GAS for WD) are discussed. © 2013 Elsevier Inc. All rights reserved.
Directory of Open Access Journals (Sweden)
Mainardi Paola
2007-10-01
Full Text Available Abstract Mowat-Wilson syndrome (MWS is a multiple congenital anomaly syndrome characterized by a distinct facial phenotype (high forehead, frontal bossing, large eyebrows, medially flaring and sparse in the middle part, hypertelorism, deep set but large eyes, large and uplifted ear lobes, with a central depression, saddle nose with prominent rounded nasal tip, prominent columella, open mouth, with M-shaped upper lip, frequent smiling, and a prominent but narrow and triangular pointed chin, moderate-to-severe intellectual deficiency, epilepsy and variable congenital malformations including Hirschsprung disease (HSCR, genitourinary anomalies (in particular hypospadias in males, congenital heart defects, agenesis of the corpus callosum and eye anomalies. The prevalence of MWS is currently unknown, but 171 patients have been reported so far. It seems probable that MWS is under-diagnosed, particularly in patients without HSCR. MWS is caused by heterozygous mutations or deletions in the Zinc finger E-box-binding homeobox 2 gene, ZEB2, previously called ZFHX1B (SIP1. To date, over 100 deletions/mutations have been reported in patients with a typical phenotype; they are frequently whole gene deletions or truncating mutations, suggesting that haploinsufficiency is the main pathological mechanism. Studies of genotype-phenotype analysis show that facial gestalt and delayed psychomotor development are constant clinical features, while the frequent and severe congenital malformations are variable. In a small number of patients, unusual mutations can lead to an atypical phenotype. The facial phenotype is particularly important for the initial clinical diagnosis and provides the hallmark warranting ZEB2 mutational analysis, even in the absence of HSCR. The majority of MWS cases reported so far were sporadic, therefore the recurrence risk is low. Nevertheless, rare cases of sibling recurrence have been observed. Congenital malformations and seizures require
Garavelli, Livia; Mainardi, Paola Cerruti
2007-01-01
Mowat-Wilson syndrome (MWS) is a multiple congenital anomaly syndrome characterized by a distinct facial phenotype (high forehead, frontal bossing, large eyebrows, medially flaring and sparse in the middle part, hypertelorism, deep set but large eyes, large and uplifted ear lobes, with a central depression, saddle nose with prominent rounded nasal tip, prominent columella, open mouth, with M-shaped upper lip, frequent smiling, and a prominent but narrow and triangular pointed chin), moderate-to-severe intellectual deficiency, epilepsy and variable congenital malformations including Hirschsprung disease (HSCR), genitourinary anomalies (in particular hypospadias in males), congenital heart defects, agenesis of the corpus callosum and eye anomalies. The prevalence of MWS is currently unknown, but 171 patients have been reported so far. It seems probable that MWS is under-diagnosed, particularly in patients without HSCR. MWS is caused by heterozygous mutations or deletions in the Zinc finger E-box-binding homeobox 2 gene, ZEB2, previously called ZFHX1B (SIP1). To date, over 100 deletions/mutations have been reported in patients with a typical phenotype; they are frequently whole gene deletions or truncating mutations, suggesting that haploinsufficiency is the main pathological mechanism. Studies of genotype-phenotype analysis show that facial gestalt and delayed psychomotor development are constant clinical features, while the frequent and severe congenital malformations are variable. In a small number of patients, unusual mutations can lead to an atypical phenotype. The facial phenotype is particularly important for the initial clinical diagnosis and provides the hallmark warranting ZEB2 mutational analysis, even in the absence of HSCR. The majority of MWS cases reported so far were sporadic, therefore the recurrence risk is low. Nevertheless, rare cases of sibling recurrence have been observed. Congenital malformations and seizures require precocious clinical
Parton densities in quantum chromodynamics gauge invariance, path-dependence and Wilson lines
Cherednikov, Igor O
2016-01-01
The purpose of this book is to give a systematic pedagogical exposition of the quantitative analysis of Wilson lines and loops in quantum chromodynamics. Using techniques from the previous volume (Wilson Lines in Quantum Field Theory, 2014), ab initio techniques are developed and practical tools for their implementation presented. An emphasis is put on their renormalization and on implications on processes observable at experimental facilities.
Exploring autocorrelations in two-flavor Wilson Lattice QCD using DD-HMC algorithm
Chowdhury, Abhishek; De, Asit K.; De Sarkar, Sangita; Harindranath, A.; Maiti, Jyotirmoy; Mondal, Santanu; Sarkar, Anwesa
2013-05-01
We perform an extensive study of the autocorrelation of several observables in lattice QCD with two degenerate flavors of unimproved Wilson fermions and Wilson gauge action using the DD-HMC algorithm. We show that (1) at a given lattice spacing, autocorrelation of topological susceptibility and unsmeared plaquette show indication of a decrease with decreasing quark mass, (2) autocorrelation of topological susceptibility and topological charge density correlator increase with decreasing lattice spacing but the effect is milder in the latter case and (3) increasing the size and the smear level increase the autocorrelation of smeared Wilson loop.
The effective action of a BPS Alice string
Energy Technology Data Exchange (ETDEWEB)
Chatterjee, Chandrasekhar; Nitta, Muneto [Keio University, Department of Physics, and Research and Education Center for Natural Sciences, Yokohama, Kanagawa (Japan)
2017-11-15
Recently a BPS Alice string has been found in a U(1) x SO(3) gauge theory coupled with three charged complex scalar fields in the triplet representation (in JHEP 1709:046 arXiv:1703.08971 [hep-th], 2017). It is a half BPS state preserving a half of the supercharges when embedded into a supersymmetric gauge theory. In this paper, we study zero modes of a BPS Alice string. After presenting U(1) and translational zero modes, we construct the effective action of these modes. In contrast to a previous analysis of the conventional Alice string for which only large distance behaviors are known, we can exactly perform a calculation in the full space thanks to the BPS properties. (orig.)
Surface defect indices and 2d-4d BPS states
Córdova, Clay; Gaiotto, Davide; Shao, Shu-Heng
2017-12-01
We conjecture a formula for the Schur index of four-dimensional N=2 theories coupled to (2, 2) surface defects in terms of the 2 d-4 d BPS spectrum in the Coulomb phase of the theory. The key ingredient in our conjecture is a refined 2 d-4 d wall-crossing invariant, which we also formulate. Our result intertwines recent conjectures expressing the four-dimensional Schur index in terms of infrared BPS particles, with the Cecotti-Vafa formula for limits of the elliptic genus in terms of two-dimensional BPS solitons. We extend our discussion to framed 2 d-4 d BPS states, and use this to demonstrate a general relationship between surface defect indices and line defect indices. We illustrate our results in the example of su(2) super Yang-Mills coupled to the ℂℙ1 sigma model defect.
Open BPS wall crossing and M-theory
International Nuclear Information System (INIS)
Aganagic, Mina; Yamazaki, Masahito
2010-01-01
Consider the degeneracies of BPS bound states of one D6-brane wrapping Calabi-Yau X with D0-branes and D2-branes. When we include D4-branes wrapping Lagrangian cycles in addition, D2-branes can end on them. These give rise to new bound states in the d=2, N=(2,2) theory of the D4-branes. We call these 'open' BPS states, in contrast to closed BPS states that arise from D-branes without boundaries. Lifting this to M-theory, we show that the generating function is captured by free Fock space spanned by M2-brane particles ending on M5-branes wrapping the Lagrangian. This implies that the open BPS bound states are counted by the square of the open topological string partition function on X, reduced to the corresponding chamber. Our results give new predictions for open BPS invariants and their wall crossing phenomena when we change the open and closed string moduli. We relate our results to the work of Cecotti and Vafa on wall crossing in the two-dimensional N=(2,2) theories. The findings from the crystal melting model for the open BPS invariants proposed recently fit well with the M-theory predictions.
Sextet Model with Wilson Fermions
DEFF Research Database (Denmark)
Hansen, Martin; Pica, Claudio
2017-01-01
We present new results from our ongoing study of the SU(3) sextet model with two flavors in the two-index symmetric representation of the gauge group. In the simulations use unimproved Wilson fermions to investigate the infrared properties of the model. We have previously presented results...
Cerebral imaging for Wilson disease; Zerebrale Bildgebung bei Morbus Wilson
Energy Technology Data Exchange (ETDEWEB)
Andersen, K.; Saleh, A. [Universitaetsklinikum Duesseldorf (Germany). Inst. fuer Diagnostische Radiologie; Suedmeyer, M. [Universitaetsklinikum Duesseldorf (Germany). Klinik fuer Neurologie
2007-03-15
Wilson disease is an autosomal recessive inherited copper metabolic disorder that is characterized by diminished biliary excretion of copper and a raised serum level of free copper. This leads to a toxic copper accumulation, particularly in the liver and the brain. Therefore, clinical symptoms are dominated by hepatic and extrapyramidal symptoms. Untreated Wilson disease has an unfavorable outcome. Cerebral changes are depicted most sensitively by magnetic resonance tomography. Pathological findings mainly focus on the basal ganglia, the midbrain and the brainstem. Depending on the therapy and the severity of the neurological symptoms, signal increase as well as signal decrease may be observed in T1-weighted (T1w) and T2-weighted (T2w) images and can be reversible when using an appropriate therapy. Hyperintense areas in T2-weighted images are induced by edema, gliosis, demyelinisation or cystic degeneration. Signal increase in T1-weighted images are found in patients with hepatic insufficiency and are probably due to manganese deposits. Signal decrease in T2-weighted images is probably caused by the paramagnetic effect of the copper accumulation. Furthermore, recent studies show a correlation between the clinical severity and changes in diffusion-weighted sequences. Although cross-section imaging plays a rather subordinate role in the primary diagnostics of Wilson disease, the described cerebral changes in patients with extrapyramidal disturbances should include Wilson disease in the differential. Persistent or progressive hyperintense lesions in T2-weighted images reflect therapy failure, and clinical recovery correlates to an improvement in MR images. Therefore, repeat MR imaging can be used to monitor medical therapy.
An Unusual Phage Repressor Encoded by Mycobacteriophage BPs.
Directory of Open Access Journals (Sweden)
Valerie M Villanueva
Full Text Available Temperate bacteriophages express transcription repressors that maintain lysogeny by down-regulating lytic promoters and confer superinfection immunity. Repressor regulation is critical to the outcome of infection-lysogenic or lytic growth-as well as prophage induction into lytic replication. Mycobacteriophage BPs and its relatives use an unusual integration-dependent immunity system in which the phage attachment site (attP is located within the repressor gene (33 such that site-specific integration leads to synthesis of a prophage-encoded product (gp33103 that is 33 residues shorter at its C-terminus than the virally-encoded protein (gp33136. However, the shorter form of the repressor (gp33103 is stable and active in repression of the early lytic promoter PR, whereas the longer virally-encoded form (gp33136 is inactive due to targeted degradation via a C-terminal ssrA-like tag. We show here that both forms of the repressor bind similarly to the 33-34 intergenic regulatory region, and that BPs gp33103 is a tetramer in solution. The BPs gp33103 repressor binds to five regulatory regions spanning the BPs genome, and regulates four promoters including the early lytic promoter, PR. BPs gp33103 has a complex pattern of DNA recognition in which a full operator binding site contains two half sites separated by a variable spacer, and BPs gp33103 induces a DNA bend at the full operator site but not a half site. The operator site structure is unusual in that one half site corresponds to a 12 bp palindrome identified previously, but the other half site is a highly variable variant of the palindrome.
Duality and BPS spectra in N = 2 supersymmetric QCD
International Nuclear Information System (INIS)
Ferrari, F.
1997-01-01
I review, with some pedagogy, two different approaches to the computation of BPS spectra in N = 2 supersymmetric QCD with gauge group SU(2). The first one is semiclassical and has been widely used in the literature. The second one makes use of constraints coming from the non perturbative, global structure of the Coulomb branch of these theories. The second method allows for a description of discontinuities in the BPS spectra at strong coupling, and should lead to accurate test of duality conjectures in N = 2 theories. (orig.)
Gauged BPS baby Skyrmions with quantized magnetic flux
Adam, C.; Wereszczynski, A.
2017-06-01
A new type of gauged BPS baby Skyrme model is presented, where the derivative term is just the Schroers current (i.e., gauge invariant and conserved version of the topological current) squared. This class of models has a topological bound saturated for solutions of the pertinent Bogomolnyi equations supplemented by a so-called superpotential equation. In contrast to the gauged BPS baby Skyrme models considered previously, the superpotential equation is linear and, hence, completely solvable. Furthermore, the magnetic flux is quantized in units of 2 π , which allows, in principle, to define this theory on a compact manifold without boundary, unlike all gauged baby Skyrme models considered so far.
On super form factors of half-BPS operators in N=4 super Yang-Mills
Energy Technology Data Exchange (ETDEWEB)
Penante, Brenda; Spence, Bill; Travaglini, Gabriele; Wen, Congkao [Centre for Research in String Theory, School of Physics and Astronomy,Queen Mary University of London, Mile End Road, London E1 4NS (United Kingdom)
2014-04-11
We compute form factors of half-BPS operators in N=4 super Yang-Mills dual to massive Kaluza-Klein modes in supergravity. These are appropriate supersymmetrisations T{sub k} of the scalar operators Tr (ϕ{sup k}) for any k, which for k = 2 give the chiral part of the stress-tensor multiplet operator. Using harmonic superspace, we derive simple Ward identities for these form factors, which we then compute perturbatively at tree level and one loop. We propose a novel on-shell recursion relation which links form factors with different numbers of fields. Using this, we conjecture a general formula for the n-point MHV form factors of T{sub k} for arbitrary k and n. Finally, we use supersymmetric generalised unitarity to derive compact expressions for all one-loop MHV form factors of T{sub k} in terms of one-loop triangles and finite two-mass easy box functions.
Loop-space quantum formulation of free electromagnetism
International Nuclear Information System (INIS)
Di Bartolo, C.; Nori, F.; Gambini, R.; Trias, A.
1983-01-01
A procedure for direct quantization of free electromagnetism in the loop-space is proposed. Explicit solutions for the loop-dependent vacuum and the Wilson loop-average are given. It is shown that elementary lines of magnetic field appear as extremals in the vacuum state as a result of the regularization procedure
Loop quantization as a continuum limit
International Nuclear Information System (INIS)
Manrique, Elisa; Oeckl, Robert; Weber, Axel; Zapata, Jose A
2006-01-01
We present an implementation of Wilson's renormalization group and a continuum limit tailored for loop quantization. The dynamics of loop-quantized theories is constructed as a continuum limit of the dynamics of effective theories. After presenting the general formalism we show as a first explicit example the 2D Ising field theory, an interacting relativistic quantum field theory with local degrees of freedom quantized by loop quantization techniques
Wade Wilson Controls NFL Defenses, Diabetes.
Thompson, K
1989-12-01
When Minnesota Vikings quarterback Wade Wilson was diagnosed with diabetes just days before the 1985 season, he scrambled to learn how to manage the disease. With his health-and perhaps his career-hanging in the balance, Wilson deftly made the life-style changes necessary to continue play.
Cognitive impairment in Wilson's disease
Directory of Open Access Journals (Sweden)
Norberto Anizio Ferreira Frota
Full Text Available Abstract Wilson's disease (WD or hepatolenticular degeneration is a rare, genetic and systemic disease, caused by a deficit in the metabolism of copper, leading to its accumulation in different organs, mainly the liver, followed by the central nervous system, especially the basal ganglia. When symptoms begin between the second and third decades of life, approximately 50% of the patients show neurological symptoms. Although dystonia and dysarthria are the most common neurological signs, cognitive changes have been reported since the first cases were described in 1912. Memory change is one of the most common impairments, but other cognitive changes have been reported, including dementia in untreated cases. In this article we review the cognitive changes in WD patients and the occurrence of dementia.
BPS dynamics of the triple (p,q) string junction
International Nuclear Information System (INIS)
Rey, S.-J.; Yee, J.-T.
1998-01-01
We study the dynamics of the triple junction of (p,q) strings in type IIB string theory. We probe the tension and mass density of (p,q) strings by studying harmonic fluctuations of the triple junction. We show that they agree perfectly with the BPS formula provided a suitable geometric interpretation of the junction is given. We provide a precise statement of the BPS limit and force-balance property. At weak coupling and sufficiently dense limit, we argue that a (p,q) string embedded in the string network is a 'wiggly string', whose low-energy dynamics can be described via a renormalization group evolved, smooth effective non-relativistic string. We also suggest the possibility that, upon type IIB strings being promoted to the M-theory membrane, there can exist 'evanescent' bound-states at the triple junction in the continuum. (orig.)
[Interstitial cystitis/bladder pain syndrome (IC/BPS)].
Scheiner, David A; Perucchini, Daniele; Fink, Daniel; Betschart, Cornelia
2015-08-19
Interstitial cystitis/bladder pain syndrome (BPS) is still an etiologically poorly understood chronic pain syndrome. BPS is a clinical diagnosis. The current treatment modalities are aimed at symptom relief because no cure is possible. Analgesics may be used at any point in treatment but preferably for short-term relief for flares or bladder pain. AUA has issued clinical practice guidelines with a stepwise approach. The first-line therapy begins with self-care and behavior modification. Physical therapy and oral medications such as amitriptyline, PPS, or antihistamines belong to the second-line therapy. Third-line therapy requires cystoscopy and hydrodistension, treatment of Hunner lesions, or intravesical use of e.g. DMSO. Neuromodulation is considered a fourth-line therapy in patients who have failed third-line treatments. Fifth-line therapies consist of intravesical injection of BoNT or oral cyclosporin A. Cystectomy is the sixth-line therapy and the treatment of last resort.
Tachyon tube on non BPS D-branes
International Nuclear Information System (INIS)
Huang Wunghong
2004-01-01
We report our searches for a single tubular tachyonic solution of regular profile on unstable non BPS D3-branes. We first show that some extended Dirac-Born-Infeld tachyon actions in which new contributions are added to avoid the Derrick's no-go theorem still could not have a single regular tube solution. Next we use the Minahan-Zwiebach tachyon action to find the regular tube solutions with circular or elliptic cross section. With a critical electric field, the energy of the tube comes entirely from the D0 and strings, while the energy associated to the tubular D2-brane tension is vanishing. We also show that fluctuation spectrum around the tube solution does not contain tachyonic mode. The results are consistent with the identification of the tubular configuration as a BPS D2-brane. (author)
N=8 non-BPS Attractors, Fixed Scalars and Magic Supergravities
Ferrara, Sergio
2008-01-01
We analyze the Hessian matrix of the black hole potential of N=8, d=4 supergravity, and determine its rank at non-BPS critical points, relating the resulting spectrum to non-BPS solutions (with non-vanishing central charge) of N=2, d=4 magic supergravities and their ``mirror'' duals. We find agreement with the known degeneracy splitting of N=2 non-BPS spectrum of generic special Kahler geometries with cubic holomorphic prepotential. We also relate non-BPS critical points with vanishing central charge in N=2 magic supergravities to a particular reduction of the N=8, 1/8-BPS critical points.
Counting BPS states of the M5-brane
Energy Technology Data Exchange (ETDEWEB)
Bonelli, Giulio [Physique Theorique et Mathematique, Universite Libre de Bruxelles, Campus Plaine C.P. 231, 1050 Bruxelles (Belgium)
2002-09-01
An on-shell model for the supersymmetric index counting multiplicities of BPS states of the M5-brane theory is reviewed. In particular we explicitly study the tensionless Little String states appearing at intersections in a bound state of N 5-branes wrapped on a six-manifold with product topology M{sub 4} x T{sup 2}. (Abstract Copyright[2002], Wiley Periodicals, Inc.)
Some exact BPS solutions for exotic vortices and monopoles
Directory of Open Access Journals (Sweden)
Handhika S. Ramadhan
2016-07-01
Full Text Available We present several analytical solutions of BPS vortices and monopoles in the generalized Abelian Maxwell–Higgs and Yang–Mills–Higgs theories, respectively. These models have recently been extensively studied and several exact solutions have already been obtained in [1,2]. In each theory, the dynamics is controlled by the additional two positive scalar-field-dependent functions, f(|ϕ| and w(|ϕ|. For the case of vortices, we work in the ordinary symmetry-breaking Higgs potential, while for the case of monopoles we have the ordinary condition of the Prasad–Sommerfield limit. Our results generalize the exact solutions found previously. We also present solutions for BPS vortices with higher winding number. These solutions suffer from the condition that w(|ϕ| has negative value at some finite range of r, but we argue that since it satisfies the weaker positive-value conditions then the corresponding energy density is still positive-definite and, thus, they are acceptable BPS solutions.
Some exact BPS solutions for exotic vortices and monopoles
Ramadhan, Handhika S.
2016-07-01
We present several analytical solutions of BPS vortices and monopoles in the generalized Abelian Maxwell-Higgs and Yang-Mills-Higgs theories, respectively. These models have recently been extensively studied and several exact solutions have already been obtained in [1,2]. In each theory, the dynamics is controlled by the additional two positive scalar-field-dependent functions, f (| ϕ |) and w (| ϕ |). For the case of vortices, we work in the ordinary symmetry-breaking Higgs potential, while for the case of monopoles we have the ordinary condition of the Prasad-Sommerfield limit. Our results generalize the exact solutions found previously. We also present solutions for BPS vortices with higher winding number. These solutions suffer from the condition that w (| ϕ |) has negative value at some finite range of r, but we argue that since it satisfies the weaker positive-value conditions then the corresponding energy density is still positive-definite and, thus, they are acceptable BPS solutions.
Open Wilson lines and generalized star product in noncommutative scalar field theories
International Nuclear Information System (INIS)
Kiem, Youngjai; Sato, Haru-Tada; Rey, Soo-Jong; Yee, Jung-Tay
2002-01-01
Open Wilson line operators and a generalized star product have been studied extensively in noncommutative gauge theories. We show that they also show up in noncommutative scalar field theories as universal structures. We first point out that the dipole picture of noncommutative geometry provides an intuitive argument for the robustness of the open Wilson lines and generalized star products therein. We calculate the one-loop effective action of noncommutative scalar field theory with a cubic self-interaction and show explicitly that the generalized star products arise in the nonplanar part. It is shown that, at the low-energy, large noncommutativity limit, the nonplanar part is expressible solely in terms of the scalar open Wilson line operator and descendants
AN EXPERIMENTAL ASSESSMENT OF THE PLATE HEAT EXCHANGER CHARACTERISTICS BY WILSON PLOT METHOD
Directory of Open Access Journals (Sweden)
Jan Opatřil
2016-10-01
Full Text Available An aim of this paper is suggestion of the evaluation method based on the experimental data and the Wilson plot method for the Plate Heat Exchangers (PHE. For the purpose of the project the new experimental loop was built for the testing of PHE to obtain the overhaul heat transfer coefficient and pressure drop between inlet and outlet of the fluid. The measurement were done for three different PHE with the performance range 30-100kW. The working fluid was water on both sides of the PHE. The differences are in number of pates as well as in extrusion profiles. The Wilson plot evaluation method was involved for the processing experimental data. To obtain more accurate correlations between the experimental data and theoretical results yield of the Wilson plot, the method was enhanced by the measured pressure drop involving. This approach could be useful for PHE designing software and for the manufacturing company.
Psychiatric comorbidity in Wilson's disease.
Mura, Gioia; Zimbrean, Paula C; Demelia, Luigi; Carta, Mauro G
2017-10-01
Wilson's disease (WD) is a relatively rare autosomal recessive inherited disorder causing copper accumulation in different organs, mainly the liver and brain. Psychiatric disturbances represent a diagnostic and therapeutic issue in WD. A search for relevant articles was carried out on PubMed/Medline, Scopus, and Google Scholar, for papers focused on psychiatric disorders in WD published between 1985-2016. Ninety-two articles were included in this review, showing the findings from 35 observational and case-control studies and 57 case reports. This study discussed the findings on the prevalence of psychiatric symptoms in WD, their impact on the life of those diagnosed, and the efficacy of available treatments on the psychiatric outcomes of WD. Psychiatric disorders are confirmed frequent in WD, with a high prevalence of mood disorders, and contribute to worse Quality-of-Life and psychosocial outcomes. Because specific therapies for WD lead to a good life expectancy, adherence to medicaments and clinical monitoring should be warranted by a multidisciplinary approach, including a hepathologic, neurologic, and psychiatric careful evaluation and education of those affected and their relatives.
Liver transplantation for Wilson disease
Catana, Andreea M; Medici, Valentina
2012-01-01
The aim of this paper is to review the current status of liver transplantation (LT) for Wilson disease (WD), focusing on indications and controversies, especially in patients with neuropsychiatric disease, and on identification of acute liver failure (ALF) cases related to WD. LT remains the treatment of choice for patients with ALF, as initial presentation of WD or when anti-copper agents are stopped, and for patients with chronic liver disease progressed to cirrhosis, unresponsive to chelating medications or not timely treated with copper chelating agents. The indication for LT in WD remains highly debated in patients with progressive neurological deterioration and failure to improve with appropriate medical treatment. In case of Wilsonian ALF, early identification is key as mortality is 100% without emergency LT. As many of the copper metabolism parameters are believed to be less reliable in ALF, simple biochemical tests have been proposed for diagnosis of acute WD with good sensitivity and specificity. LT corrects copper metabolism and complications resulting from WD with excellent 1 and 5 year survival. Living related liver transplantation represents an alternative to deceased donor LT with excellent long-term survival, without disease recurrence. Future options may include hepatocyte transplantation and gene therapy. Although both of these have shown promising results in animal models of WD, prospective human studies are much needed to demonstrate their long-term beneficial effects and their potential to replace the need for medical therapy and LT in patients with WD. PMID:22312450
Advances in intravesical therapy for bladder pain syndrome (BPS)/interstitial cystitis (IC).
Meng, En; Hsu, Yu-Chao; Chuang, Yao-Chi
2018-01-01
Bladder pain syndrome (BPS)/interstitial cystitis (IC) is a chronic symptom complex that may cause bothersome storage symptoms and pain or discomfort of the bladder, adversely affecting a patient's quality of life. The etiology of IC/BPS remains unclear, and its cause may be multifactorial. Diagnosis of IC/BPS is based on clinical features, and the possibility of other conditions must be ruled out first. Although no definitive treatment is currently available for IC/BPS, various intravesical therapies are used for IC/BPS, including heparin, hyaluronic acid, chondroitin sulfate, pentosan polysulfate, dimethylsulfoxide, liposomes, and botulinum onabotulinumtoxinA (BoNT-A). This review summarizes the intravesical therapy for IC/BPS and discusses recent advances in the instillation of liposomal-mediated BoNT-A and other newly developed intravesical therapies. © 2018 John Wiley & Sons Australia, Ltd.
BPS States in the Duality Web of the Omega deformation
Hellerman, Simeon; Reffert, Susanne
2013-01-01
In this note, we study different limits of an Omega-deformed (2,0) six-dimensional gauge theory realized in a M-theory fluxtrap background. Via a chain of dualities, we connect the Omega-deformed SYM to a new four-dimensional gauge theory which we refer to as the reciprocal gauge theory. This theory has several properties in common with Liouville field theory, such as its gauge coupling b^2 =\\epsilon_2 / \\epsilon_1, and its behavior under S-duality. Finally, we realize the BPS states on the SYM side of the AGT correspondence and follow them along the chain of dualities. In the fluxtrap frame, we are dealing with two distinct types of states localized in different radial positions, while in the reciprocal frame, we find single states carrying both charges localized in one place which appear to be perturbatively stable. Our microscopic picture of the small-b limit exhibits semiclassically BPS bound states, which are not visible at the level of the partition function.
Gauge theory loop operators and Liouville theory
Energy Technology Data Exchange (ETDEWEB)
Drukker, Nadav [Humboldt Univ. Berlin (Germany). Inst. fuer Physik; Gomis, Jaume; Okuda, Takuda [Perimeter Inst. for Theoretical Physics, Waterloo, ON (Canada); Teschner, Joerg [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany)
2009-10-15
We propose a correspondence between loop operators in a family of four dimensional N=2 gauge theories on S{sup 4} - including Wilson, 't Hooft and dyonic operators - and Liouville theory loop operators on a Riemann surface. This extends the beautiful relation between the partition function of these N=2 gauge theories and Liouville correlators found by Alday, Gaiotto and Tachikawa. We show that the computation of these Liouville correlators with the insertion of a Liouville loop operator reproduces Pestun's formula capturing the expectation value of a Wilson loop operator in the corresponding gauge theory. We prove that our definition of Liouville loop operators is invariant under modular transformations, which given our correspondence, implies the conjectured action of S-duality on the gauge theory loop operators. Our computations in Liouville theory make an explicit prediction for the exact expectation value of 't Hooft and dyonic loop operators in these N=2 gauge theories. The Liouville loop operators are also found to admit a simple geometric interpretation within quantum Teichmueller theory as the quantum operators representing the length of geodesics. We study the algebra of Liouville loop operators and show that it gives evidence for our proposal as well as providing definite predictions for the operator product expansion of loop operators in gauge theory. (orig.)
Wilson lines and UV sensitivity in magnetic compactifications
Ghilencea, D. M.; Lee, Hyun Min
2017-06-01
We investigate the ultraviolet (UV) behaviour of 6D N=1 supersymmetric effective (Abelian) gauge theories compactified on a two-torus ( T 2) with magnetic flux. To this purpose we compute offshell the one-loop correction to the Wilson line state self-energy. The offshell calculation is actually necessary to capture the usual effective field theory expansion in powers of (∂ /Λ). Particular care is paid to the regularization of the (divergent) momentum integrals, which is relevant for identifying the corresponding counterterm(s). We find a counterterm which is a new higher dimensional effective operator of dimension d=6, that is enhanced for a larger compactification area (where the effective theory applies) and is consistent with the symmetries of the theory. Its consequences are briefly discussed and comparison is made with orbifold compactifications without flux.
ON-SHELL IMPROVEMENT OF THE MASSIVE WILSON QUARK ACTION.
Energy Technology Data Exchange (ETDEWEB)
AOKI, S.; KAYABA, Y.; KURAMASHI, Y.; YAMADA, N.
2005-04-01
We review a relativistic approach to the heavy quark physics in lattice QCD by applying a relativistic O(a) improvement to the massive Wilson quark action on the lattice. After explaining how power corrections of m{sub Q}a can be avoided and remaining uncertainties are reduced to be of order (a{Lambda}{sub QCD}){sup 2}, we demonstrate a determination of four improvement coefficients in the action up to one-loop level in a mass dependent way. We also show a perturbative determination of mass dependent renormalization factors and O(a) improvement coefficients for the vector and axial vector currents. Some preliminary results of numerical simulations are also presented.
One-loop anisotropy for improved actions
Perez, Margarita Garcia; van Baal, Pierre
1996-01-01
We determine the one-loop correction to the anisotropy factor for the square Symanzik improved lattice action, extracted fromthe finite volume effective action for SU(N) gauge theories in the background of a zero-momentum gauge field. The result is smaller by approximately a factor 3 than the one-loop correction for the anisotropic Wilson action. We also comment on the Hamiltonian limit.
Loop variables in the geometry of a rotating black string
International Nuclear Information System (INIS)
Carvalho, A M de M; Moraes, Fernando; Furtado, Claudio
2003-01-01
In this paper we analyse in the Wilson loop context the parallel transport of vectors and spinors around a closed loop in the background spacetime of a rotating black string in order to classify its global properties. We also examine particular closed orbits in this spacetime and verify the Mandelstam relations
Wang, Guangjun; Yu, Ermeng; Li, Zhifei; Yu, Deguang; Wang, Haiying; Gong, Wangbao
2016-06-01
The present study was conducted to evaluate the feasibility of replacing fish meal (FM) with bioactive peptides (BPs) in diet of white shrimp ( Litopenaeus vannamei). The changes in growth performance, body composition, non-specific immunity, and water quality were examined after the shrimp were fed four diets, in which 0% (control), 33.3%, 66.7% and 100% of FM was replaced by BPs, respectively. The groups were designated as Con, 1/3BPs, 2/3BPs, and 3/3BPs. A total of 720 shrimp with an initial body weight of 1.46 ± 0.78 g were fed the experimental diets for 56 days. The results revealed that: 1) the weight gain rate (WGR) in 1/3BPs, 2/3BPs, and 3/3BPs was significantly higher than that in Con ( P < 0.05), while no significant difference was found on survival rate and feed conversion ratio (FCR); 2) the whole-body crude protein (CP) and crude lipids (CL) were significantly different among groups, while there was no significant difference between crude ash and phosphorus contents; 3) the levels of acid phosphatase (ACP), lysozyme (LZM), superoxide dismutase (SOD), phenol oxidase (PO) and bactericidal activity increased significantly with the inclusion of BPs; 4) in terms of water quality, no significant difference was found in pH and dissolved oxygen among diets during the whole experimental period. Moreover, even though nitrite and ammonium levels tended to increase with time, there was no significant difference among groups. The results indicated that BPs is an applicable alternative of protein source, which can substitute FM in the diets of L. vannamei; it is able to effectively promote growth performance and improve immunity. Moreover, BPs in the diets had no negative impact on water quality.
Wilson-'t Hooft operators in four-dimensional gauge theories and S-duality
Kapustin, Anton
2006-07-01
We study operators in four-dimensional gauge theories which are localized on a straight line, create electric and magnetic flux, and in the UV limit break the conformal invariance in the minimal possible way. We call them Wilson-’t Hooft operators, since in the purely electric case they reduce to the well-known Wilson loops, while in general they may carry ’t Hooft magnetic flux. We show that to any such operator one can associate a maximally symmetric boundary condition for gauge fields on AdSE2×S2. We show that Wilson-’t Hooft operators are classified by a pair of weights (electric and magnetic) for the gauge group and its magnetic dual, modulo the action of the Weyl group. If the magnetic weight does not belong to the coroot lattice of the gauge group, the corresponding operator is topologically nontrivial (carries nonvanishing ’t Hooft magnetic flux). We explain how the spectrum of Wilson-’t Hooft operators transforms under the shift of the θ-angle by 2π. We show that, depending on the gauge group, either SL(2,Z) or one of its congruence subgroups acts in a natural way on the set of Wilson-’t Hooft operators. This can be regarded as evidence for the S-duality of N=4 super-Yang-Mills theory. We also compute the one-point function of the stress-energy tensor in the presence of a Wilson-’t Hooft operator at weak coupling.
Non-BPS multi-bubble microstate geometries
Energy Technology Data Exchange (ETDEWEB)
Bena, Iosif [Institut de Physique Théorique, Université Paris Saclay, CEA, CNRS,91191 Gif sur Yvette (France); Bossard, Guillaume [Centre de Physique Théorique, Ecole Polytechnique, CNRS, Université Paris-Saclay, 91128 Palaiseau Cedex (France); Katmadas, Stefanos [Dipartimento di Fisica, Università di Milano-Bicocca and INFN, Sezione di Milano-Bicocca,Milano (Italy); Turton, David [Institut de Physique Théorique, Université Paris Saclay, CEA, CNRS,91191 Gif sur Yvette (France)
2016-02-11
We construct the first smooth horizonless supergravity solutions that have two topologically-nontrivial three-cycles supported by flux, and that have the same mass and charges as a non-extremal D1-D5-P black hole. Our configurations are solutions to six-dimensional ungauged supergravity coupled to a tensor multiplet, and uplift to solutions of Type IIB supergravity. The solutions represent multi-center generalizations of the non-BPS solutions of Jejjala, Madden, Ross, and Titchener, which have over-rotating angular momenta. By adding an additional Gibbons-Hawking center, we succeed in lowering one of the two angular momenta below the cosmic censorship bound, and bringing the other very close to this bound. Our results demonstrate that it is possible to construct multi-center horizonless solutions corresponding to non-extremal black holes, and offer the prospect of ultimately establishing that finite-temperature black holes have nontrivial structure at the horizon.
Superconformal interpretation of BPS states in AdS geometries
Ferrara, Sergio; Ferrara, Sergio; Sokatchev, Emery
2001-01-01
We carry out a general analysis of the representations of the superconformal algebras SU(2,2/N), OSp(8/4,R) and OSp(8^*/4) and give their realization in superspace. We present a construction of their UIR's by multiplication of the different types of massless superfields ("supersingletons"). Particular attention is paid to the so-called "short multiplets". Representations undergoing shortening have "protected dimension" and correspond to BPS states in the dual supergravity theory in anti-de Sitter space. These results are relevant for the classification of multitrace operators in boundary conformally invariant theories as well as for the classification of AdS black holes preserving different fractions of supersymmetry.
(BPS) Fayet-Iliopoulos Terms in 5D Orbifold SUGRA
Paccetti-Correia, F; Tavartkiladze, Z; Correia, Filipe Paccetti; Schmidt, Michael G.; Tavartkiladze, Zurab
2005-01-01
We discuss Fayet-Iliopoulos terms in the context of five-dimensional supergravity compactified on an orbifold. For this purpose we use our superfield formulation of the off-shell 5D SUGRA. In the case of tuned FI terms, contrary to other claims, we find BPS solutions which ensure that N=1 supersymmetry is unbroken also in warped geometries. As in the rigid case, the FI terms induce odd masses for charged hypermultiplets, leading to the (de)localisation of the KK wave-functions near the fix-point branes. In the case of ungauged U(1)_R symmetry, we present also supersymmetric warped solutions in the presence of non-trivial profiles of charged hyperscalars.
Symmetries of the refined D1/D5 BPS spectrum
Benjamin, Nathan; Harrison, Sarah M.
2017-11-01
We examine the large N 1/4-BPS spectrum of the symmetric orbifold CFT Sym N ( M ) deformed to the supergravity point in moduli space for M = K3 and T 4. We consider refinement under both left- and right-moving SU(2) R symmetries of the superconformal algebra, and decompose the spectrum into characters of the algebra. We find that at large N the character decomposition satisfies an unusual property, in which the degeneracy only depends on a certain linear combination of left- and right-moving quantum numbers, suggesting deeper symmetry structure. Furthermore, we consider the action of discrete symmetry groups on these degeneracies, where certain subgroups of the Conway group are known to play a role. We also comment on the potential for larger discrete symmetry groups to appear in the large N limit.
BPS limit of multi- D- and DF-strings in boundary string field theory
International Nuclear Information System (INIS)
Go, Gyungchoon; Ishida, Akira; Kim, Yoonbai
2007-01-01
A BPS limit is systematically derived for straight multi- D- and DF-strings from the D3D-bar3 system in the context of boundary superstring field theory. The BPS limit is obtained in the limit of thin D(F)-strings, where the Bogomolny equation supports singular static multi-D(F)-string solutions. For the BPS multi-string configurations with arbitrary separations, BPS sum rule is fulfilled under a Gaussian type tachyon potential and reproduces exactly the descent relation. For the DF-strings ((p,q)-strings), the distribution of fundamental string charge density coincides with its energy density and the Hamiltonian density takes the BPS formula of square-root form
Wilson disease : from clinical to molecular
Houwen, Roderick Henk Johan
1991-01-01
Wilson disease is an autosomal recessive copper storage disease. It is characterized by an inability of the liver to; excrete copper into bile and to incorporate copper into ceruloplasmin. This results in a gradual accumulation of copper in the liver and subsequently in the brain and other organs,
SU(3) sextet model with Wilson fermions
DEFF Research Database (Denmark)
Hansen, Martin; Drach, Vincent; Pica, Claudio
2017-01-01
to be inside or very close to the lower boundary of the conformal window. We use the Wilson discretization for the fermions and map the phase structure of the lattice model. We study several spectral and gradient flow observables both in the bulk and the weak coupling phases. While in the bulk phase we find...
Wilson Fermions with Four Fermion Interactions
DEFF Research Database (Denmark)
Rantaharju, Jarno; Drach, Vincent; Hietanen, Ari
2015-01-01
We present a lattice study of a four fermion theory, known as Nambu Jona-Lasinio (NJL) theory, via Wilson fermions. Four fermion interactions naturally occur in several extensions of the Standard Model as a low energy parameterisation of a more fundamental theory. In models of dynamical electroweak...
CLASSICS Kenneth G. Wilson – Biographical
Indian Academy of Sciences (India)
His father, E Bright Wilson, was a student of the great. Linus Pauling, a member of the ... Harvard University; my mother had one year of graduate work in physics before her marriage. My grandfather on my ... Imagination by Kasner and Newman, and went on to work through a calculus text, until. I got stuck in a chapter on ...
Cora Wilson Stewart: Crusader against Illiteracy.
Nelms, Willie
This book is a biography of Cora Wilson Stewart, a Rowan County, Kentucky, school superintendent who rose to prominence with the establishment of the Moonlight Schools for adults with low literacy levels in 1911. It presents the details of her Kentucky crusade against illiteracy, then examines the personal part of her life as well as her later…
Indian Academy of Sciences (India)
perceptions of strongly interacting systems – either in particle physics or in condensed matter. The Nobel citation mentions the cryptic term 'renormalization group'. An article elsewhere in this issue ... young research student who had graduated from Harvard University in 1956 – Kenneth Wilson. Gell-Mann suggested that ...
Spectrum of the Wilson Dirac operator at finite lattice spacings
DEFF Research Database (Denmark)
Akemann, G.; Damgaard, Poul Henrik; Splittorff, Kim
2011-01-01
We consider the effect of discretization errors on the microscopic spectrum of the Wilson Dirac operator using both chiral Perturbation Theory and chiral Random Matrix Theory. A graded chiral Lagrangian is used to evaluate the microscopic spectral density of the Hermitian Wilson Dirac operator...... as well as the distribution of the chirality over the real eigenvalues of the Wilson Dirac operator. It is shown that a chiral Random Matrix Theory for the Wilson Dirac operator reproduces the leading zero-momentum terms of Wilson chiral Perturbation Theory. All results are obtained for fixed index...... of the Wilson Dirac operator. The low-energy constants of Wilson chiral Perturbation theory are shown to be constrained by the Hermiticity properties of the Wilson Dirac operator....
Open Wilson lines as states of closed string
International Nuclear Information System (INIS)
Murakami, Koichi; Nakatsu, Toshio
2003-01-01
A system of a D-brane in bosonic string theory on a constant B field background is studied in order to obtain further insight into the bulk-boundary duality. Boundary states which describe arbitrary numbers of open-string tachyons and gluons are given. The UV behavior of field theories on the non-commutative world-volume is investigated by using these states. We take the zero-slope limits of the generating functions of one-loop amplitudes of gluons (and open-string tachyons) in which the region of the small open-string proper time is magnified. The existence of a B field allows the limits to be slightly different from the standard field theory limits of a closed-string. These limits enable us to obtained world-volume theories at a trans-string scale. In this limit the generating functions are shown to be factorized into two curved open Wilson lines (and their analogues) and become integrals on the space of paths with a Gaussian distribution around straight lines. These facts indicate the possibility that field theories on the non-commutative world-volume are topological at such a trans-string scale. We also give a proof of the Dhar-Kitazawa conjecture by determining an explicit correspondence between the closed-string states and the paths. Momentum eigenstates of closed-string or momentum loops also play an important role in these analyses. (author)
Waterborne exposure to BPS causes thyroid endocrine disruption in zebrafish larvae.
Directory of Open Access Journals (Sweden)
Dan-Hua Zhang
Full Text Available Bisphenol S (BPS is widely used as a raw material in industry, resulting in its ubiquitous distribution in natural environment, including the aqueous environment. However, the effect of BPS on the thyroid endocrine system is largely unknown. In this study, zebrafish (Danio rerio embryos were exposed to BPS at 1, 3, 10, and 30 μg/L, from 2 h post-fertilization (hpf to 168hpf. Bioconcentration of BPS and whole-body thyroid hormones (THs, thyroid-stimulating hormone (TSH concentrations as well as transcriptional profiling of key genes related to the hypothalamic-pituitary-thyroid (HPT axis were examined. Chemical analysis indicated that BPS was accumulated in zebrafish larvae. Thyroxine (T4 and triiodothyronine (T3 levels were significantly decreased at ≥ 10 and 30 μg/L of BPS, respectively. However, TSH concentration was significantly induced in the 10 and 30 μg/L BPS-treated groups. After exposure to BPS, the mRNA expression of corticotrophin releasing hormone (crh and thyroglobulin (tg genes were up-regulated at ≥10 μg/L of BPS, in a dose-response manner. The transcription of genes involved in thyroid development (pax8 and synthesis (sodium/iodide symporter, slc5a5 were also significantly increased in the 30 μg/L of BPS treatment group. Moreover, exposure to 10 μg/L or higher concentration of BPS significantly up-regulated genes related to thyroid hormone metabolism (deiodinases, dio1, dio2 and uridinediphosphate glucoronosyltransferases, ugt1ab, which might be responsible for the altered THs levels. However, the transcript of transthyretin (ttr was significantly down-regulated at ≥ 3 μg/L of BPS, while the mRNA levels of thyroid hormone receptors (trα and trβ and dio3 remained unchanged. All the results indicated that exposure to BPS altered the whole-body THs and TSH concentrations and changed the expression profiling of key genes related to HPT axis, thus triggering thyroid endocrine disruption.
Energy Technology Data Exchange (ETDEWEB)
Nimmo, D.; Willox, M.; Hoefs, N.; Kondratieff, B.; Steidl-Pulley, T. [Colorado State Univ., Fort Collins, CO (United States); Beeson, D.
1995-12-31
Wilson`s Creek is a tributary of the James River in southwestern Missouri that flows from the urban area of Springfield through Wilson`s Creek National Battlefield Park. Previous investigators identified poor water quality in Wilson`s Creek and reported several fish kill incidences in the watershed. Water quality problems are complicated by a marked increase in urbanization within the watershed and the interaction of surface water with a complex karst groundwater system. The objective of this study was to use macroinvertebrate and fish communities, single species bioassays, and toxicity identification procedures (TIEs) to identify contaminants and their sources. Macroinvertebrate and fish indices as well as Ceriodaphnia dubia test indicated upstream contaminants were affecting water quality in the park. Toxicity identification procedures suggested that metals were likely responsible for the toxicity. Four samples from Wilson`s Creek showed zinc exceeding 25 parts-per-billion (ppb); nickel at about 20 ppb with occasional incidences of copper and industrial organics.
The spacetime life of a non-BPS D-particle
International Nuclear Information System (INIS)
Eyras, E.
2000-04-01
We investigate the classical geometry generated by a stable non-BPS D-particle. We consider the boundary state of a stable non-BPS D-particle in the covariant formalism in the type IIB theory orbifolded by (-1) F L ·I 4 . We calculate the scattering amplitude between two D-particles in the non-compact and compact orbifold and analyse the short and long distance behaviour. At short distances we find no force at order υ 2 for any radius, and at the critical radius we find a BPS-like behaviour up to υ 4 corrections for long and short distances. Projecting the boundary state on the massless states of the orbifold closed string spectrum we obtain the large distance behaviour of the classical solution describing this non-BPS D-particle in the non-compact and compact cases. By using the non-BPS D-particle as a probe of the background geometry of another non-BPS D-particle, we recover the no-force condition at the critical radius and the υ 2 behaviour of the probe. Moreover, assuming that the no-force persists for the complete geometry we derive part of the classical solution for the non-BPS D-particle. (author)
BPS algebras, genus zero and the heterotic Monster
Paquette, Natalie M.; Persson, Daniel; Volpato, Roberto
2017-10-01
In this note, we expand on some technical issues raised in (Paquette et al 2016 Commun. Number Theory Phys. 10 433-526) by the authors, as well as providing a friendly introduction to and summary of our previous work. We construct a set of heterotic string compactifications to 0 + 1 dimensions intimately related to the Monstrous moonshine module of Frenkel, Lepowsky, and Meurman (and orbifolds thereof). Using this model, we review our physical interpretation of the genus zero property of Monstrous moonshine. Furthermore, we show that the space of (second-quantized) BPS-states forms a module over the Monstrous Lie algebras mg —some of the first and most prominent examples of Generalized Kac-Moody algebras—constructed by Borcherds and Carnahan. In particular, we clarify the structure of the module present in the second-quantized string theory. We also sketch a proof of our methods in the language of vertex operator algebras, for the interested mathematician.
Wilson lines in the MHV action
Kotko, P.; Stasto, A. M.
2017-09-01
The MHV action is the Yang-Mills action quantized on the light-front, where the two explicit physical gluonic degrees of freedom have been canonically transformed to a new set of fields. This transformation leads to the action with vertices being off-shell continuations of the MHV amplitudes. We show that the solution to the field transformation expressing one of the new fields in terms of the Yang-Mills field is a certain type of the Wilson line. More precisely, it is a straight infinite gauge link with a slope extending to the light-cone minus and the transverse direction. One of the consequences of that fact is that certain MHV vertices reduced partially on-shell are gauge invariant — a fact discovered before using conventional light-front perturbation theory. We also analyze the diagrammatic content of the field transformations leading to the MHV action. We found that the diagrams for the solution to the transformation (given by the Wilson line) and its inverse differ only by light-front energy denominators. Further, we investigate the coordinate space version of the inverse solution to the one given by the Wilson line. We find an explicit expression given by a power series in fields. We also give a geometric interpretation to it by means of a specially defined vector field. Finally, we discuss the fact that the Wilson line solution to the transformation is directly related to the all-like helicity gluon wave function, while the inverse functional is a generating functional for solutions of self-dual Yang-Mills equations.
Ted Wilson passes on the torch
2003-01-01
As part of the Laboratory's outreach programme, the CERN Accelerator School (CAS) brings together students and experienced physicists from all over the world with the aim of promoting the understanding of accelerator physics. As head of the School for 11 years, Ted Wilson became a CERN ambassador to the outside community. He retired in March, handing over the reigns of the CAS to Daniel Brandt. Ted Wilson and his assistant, Suzanne von Wartburg, during an EPAC meeting in 1994.The accelerator schools allowed some time for relaxation in the local surrounding for students as well as for the director of CAS.As a boy, Ted Wilson could have embarked on a career in pop music rather than physics, rubbing shoulders at secondary school in Liverpool with two of the future Beatles. But prefering classical music and answering the call of science, he took the more serious of the two paths, studying physics first at Oxford University then at the Rutherford Laboratory. After a year at CERN and four years at the Rutherford La...
Psychiatric aspects of Wilson disease: a review.
Zimbrean, Paula C; Schilsky, Michael L
2014-01-01
To review the current evidence about psychiatric symptoms in Wilson's disease (WD). We searched Ovid, PsychInfo, CINHAL and PubMed databases from May 1946 to May 2012 using the key words Wilson('s) disease in combination with psychiatry, psychiatric, psychosis, schizophrenia, depression, mania, bipolar, mood, anxiety, personality and behavior. Psychiatric symptoms occur before, concurrent with or after the diagnosis and treatment for WD. Thirty to forty percent of patients have psychiatric manifestations at the time of diagnosis, and 20% had seen a psychiatrist prior to their WD diagnosis. When psychiatric symptoms preceded neurological or hepatic involvement, the average time between the psychiatric symptoms and the diagnosis of WD was 864.3 days. The prevalence of psychiatric disorders in WD patients varies wildly (major depressive disorder, 4-47%; psychosis, 1.4-11.3%). Certain gene mutations of ATP7B may correlate with specific personality traits. Psychiatric manifestations represent a significant part of the clinical presentation of WD and can present at any point in the course of the illness. Psychiatric manifestations occurring without overt hepatic or neurologic involvement may lead to misdiagnosis. A better understanding of the psychiatric presentations in WD may provide insights into the underlying mechanisms of psychiatric disorders. © 2014.
The Legacy of G. Wilson Knight
Directory of Open Access Journals (Sweden)
Raw Laurence
2017-06-01
Full Text Available G. Wilson Knight (1897-1985 was one of the most influential Shakespearean critics of the mid-twentieth century. This piece surveys his work from 1930 until the early 1980s. Much affected by the First World War, he developed a style of criticism based on Christian principles of respect for other people and belief in an all-powerful God. Many of his most famous pieces (in THE WHEEL OF FIRE, for instance argue for human insignificance in an indifferent universe. It is up to all of us as individuals to develop methods of coping with this world. Wilson Knight’s ideas gained particular currency during the Second World War, when Britain’s very future seemed at risk due to the threat of Nazi invasion. Although much derided for his use of transcendent language—especially by his contemporary F. R. Leavis—Wilson Knight’s ideas seem to have acquired new significance in a globalized world, where individuals fight to main their identity in a technology-driven environment.
Clinical zinc deficiency as early presentation of Wilson disease.
Van Biervliet, Stephanie; Küry, Sébastien; De Bruyne, Ruth; Vanakker, Olivier M; Schmitt, Sébastien; Vande Velde, Saskia; Blouin, Eric; Bézieau, Stéphane
2015-04-01
Wilson disease is a rare autosomal recessive disorder of the copper metabolism caused by homozygous or compound heterozygous mutations in the ATP-ase Cu(2+) transporting polypeptide (ATP7B) gene. The copper accumulation in different organs leads to the suspicion of Wilson disease. We describe a child with clinical zinc deficiency as presenting symptom of Wilson disease, which was confirmed by 2 mutations within the ATP7B gene and an increased copper excretion.
Wilson and Gisvold's textbook of organic medicinal and pharmaceutical chemistry
National Research Council Canada - National Science Library
Wilson, Charles Owens; Beale, John Marlowe; Block, John H
2011-01-01
"For over half a century, Wilson and Gisvold's Textbook of Organic Medicinal and Pharmaceutical Chemistry has served the discipline of medicinal chemistry for both graduate and undergraduate pharmacy...
Wilson fermion determinant in lattice QCD
International Nuclear Information System (INIS)
Nagata, Keitaro
2014-01-01
In this paper, the contraction formula for the fermion matrix is explained. The contraction formula is partly executed analytically only for the imaginary time component of the fermion matrices. It is utilized because the fermion matrices calculations are executed very effectively and it is also possible to get the analytical representation of the chemical potential. It is often used in the simulations of the finite density lattice QCD. The method to analytically calculate the imaginary time component of the fermion matrices is described in the case of fermion action called as the Wilson fermion. To explain the situation, the meaning of QCD, its non-perturbative properties, the sign problem of the quark chemical potentials etc. are mentioned. Then it is explained 'Why the fermion matrices are considered?' Then in the overall contraction formula explanation of the Wilson fermion matrices, the structure of the fermion matrices is described and the matrices calculations by using the exchange matrices are shown. The physical meaning of the contraction formula is given at the end. Finally some examples of the applications of this method are related for explanation. (S. Funahashi)
Evolution and functional diversity of the Calcium Binding Proteins (CaBPs
Directory of Open Access Journals (Sweden)
Lee P Haynes
2012-02-01
Full Text Available The mammalian central nervous system (CNS exhibits a remarkable ability to process, store and transfer information. Key to these activities is the use of highly regulated and unique patterns of calcium signals encoded by calcium channels and decoded by families of specific calcium-sensing proteins. The largest family of eukaryotic calcium sensors are those related to the small EF-hand containing protein calmodulin (CaM. In order to maximise the usefulness of calcium as a signalling species and to permit the evolution and fine tuning of the mammalian CNS, families of related proteins have arisen that exhibit characteristic calcium binding properties and tissue-, cellular- and sub-cellular distribution profiles. The Calcium Binding Proteins (CaBPs represent one such family of vertebrate specific calmodulin like proteins that have emerged in recent years as important regulators of essential neuronal target proteins. Bioinformatic analyses indicate that the CaBPs consist of two subfamilies and that the ancestral members of these are CaBP1 and CaBP8. The CaBPs have distinct intracellular localisations based on different targeting mechanisms including a novel type-II transmembrane domain in CaBPs 7 and 8. Recent work has led to the identification of new target interactions and possible functions for the CaBPs suggesting that they have multiple physiological roles with relevance for the normal functioning of the CNS.
Characterization of an endolysin, LysBPS13, from a Bacillus cereus bacteriophage.
Park, Jaeeun; Yun, Jiae; Lim, Jeong-A; Kang, Dong-Hyun; Ryu, Sangryeol
2012-07-01
Use of bacteriophages as biocontrol agents is a promising tool for controlling pathogenic bacteria including antibiotic-resistant bacteria. Not only bacteriophages but also endolysins, the peptidoglycan hydrolyzing enzymes encoded by bacteriophages, have high potential for applications as biocontrol agents against food-borne pathogens. In this study, a putative endolysin gene was identified in the genome of the bacteriophage BPS13, which infects Bacillus cereus. In silico analysis of this endolysin, designated LysBPS13, showed that it consists of an N-terminal catalytic domain (PGRP domain) and a C-terminal cell wall binding domain (SH3_5 domain). Further characterization of the purified LysBPS13 revealed that this endolysin is an N-acetylmuramyl-l-alanine amidase, the activity of which was not influenced by addition of EDTA. In addition, LysBPS13 demonstrated remarkable thermostability in the presence of glycerol, and it retained its lytic activity even after incubation at 100 °C for 30 min. Taken together, these results indicate that LysBPS13 can be considered a favorable candidate for a new antimicrobial agent to control B. cereus. © 2012 Federation of European Microbiological Societies. Published by Blackwell Publishing Ltd. All rights reserved.
Bootstrapping the Three-Loop Hexagon
Energy Technology Data Exchange (ETDEWEB)
Dixon, Lance J.; /CERN /SLAC; Drummond, James M.; /CERN /Annecy, LAPTH; Henn, Johannes M.; /Humboldt U., Berlin /Santa Barbara, KITP
2011-11-08
We consider the hexagonal Wilson loop dual to the six-point MHV amplitude in planar N = 4 super Yang-Mills theory. We apply constraints from the operator product expansion in the near-collinear limit to the symbol of the remainder function at three loops. Using these constraints, and assuming a natural ansatz for the symbol's entries, we determine the symbol up to just two undetermined constants. In the multi-Regge limit, both constants drop out from the symbol, enabling us to make a non-trivial confirmation of the BFKL prediction for the leading-log approximation. This result provides a strong consistency check of both our ansatz for the symbol and the duality between Wilson loops and MHV amplitudes. Furthermore, we predict the form of the full three-loop remainder function in the multi-Regge limit, beyond the leading-log approximation, up to a few constants representing terms not detected by the symbol. Our results confirm an all-loop prediction for the real part of the remainder function in multi-Regge 3 {yields} 3 scattering. In the multi-Regge limit, our result for the remainder function can be expressed entirely in terms of classical polylogarithms. For generic six-point kinematics other functions are required.
Density-dependent mass gain by Wilson's Warblers during stopover
Jeffrey F. Kelly; Linda S. DeLay; Deborah M. Finch
2002-01-01
The need restore energetic reserves at stopover sites constrains avian migration ecology. To describe that constraint, we examined relationships among mass gained by Wilson's Warblers (Wilsonia pusilla) during stopover, abundance of Wilson's Warblers (i.e. capture rate), and arthropod abundance during autumn migration. We found that amount...
Woodrow Wilson: Prophet of Peace. Teaching with Historic Places.
Goehner, Thomas B.
This lesson describes President Woodrow Wilson's struggle with and his ultimate failure at achieving lasting world peace through the League of Nations. The lesson focuses on November 23, 1923, the eve of the fifth anniversary of the Armistice that concluded World War I, when a frail and ill Wilson was ready to deliver a commemorative address by…
Protected couplings and BPS dyons in half-maximal supersymmetric string vacua
Directory of Open Access Journals (Sweden)
Guillaume Bossard
2017-02-01
Full Text Available We analyze four- and six-derivative couplings in the low energy effective action of D=3 string vacua with half-maximal supersymmetry. In analogy with an earlier proposal for the (∇Φ4 coupling, we propose that the ∇2(∇Φ4 coupling is given exactly by a manifestly U-duality invariant genus-two modular integral. In the limit where a circle in the internal torus decompactifies, the ∇2(∇Φ4 coupling reduces to the ∇2F4 and R2F2 couplings in D=4, along with an infinite series of corrections of order e−R, from four-dimensional 1/4-BPS dyons whose worldline winds around the circle. Each of these contributions is weighted by a Fourier coefficient of a meromorphic Siegel modular form, explaining and extending standard results for the BPS index of 1/4-BPS dyons.
6d → 5d → 4d reduction of BPS attractors in flat gauged supergravities
Directory of Open Access Journals (Sweden)
Kiril Hristov
2015-08-01
This is achieved starting from the BPS black string in 6d with an AdS3×S3 attractor and taking two different routes to arrive at a 1/2 BPS AdS2×S2 attractor of a non-BPS black hole in 4d N=2 flat gauged supergravity. The two inequivalent routes interchange the order of KK reduction on AdS3 and SS reduction on S3. We also find the commutator between the two operations after performing a duality transformation: on the level of the theory the result is the exchange of electric with magnetic gaugings; on the level of the solution we find a flip of the quartic invariant I4 to −I4.
The universal one-loop effective action
Energy Technology Data Exchange (ETDEWEB)
Drozd, Aleksandra [Theoretical Particle Physics and Cosmology Group, Physics Department, King’s College London,Strand, London, WC2R 2LS (United Kingdom); Ellis, John [Theoretical Particle Physics and Cosmology Group, Physics Department, King’s College London,Strand, London, WC2R 2LS (United Kingdom); TH Division, Physics Department, CERN,Route de Meyrin, Geneva 23, CH-1211 (Switzerland); Quevillon, Jérémie [Theoretical Particle Physics and Cosmology Group, Physics Department, King’s College London,Strand, London, WC2R 2LS (United Kingdom); You, Tevong [Theoretical Particle Physics and Cosmology Group, Physics Department, King’s College London,Strand, London, WC2R 2LS (United Kingdom); Cavendish Laboratory, University of Cambridge,J.J. Thomson Avenue, Cambridge, CB3 0HE (United Kingdom); DAMTP, University of Cambridge,Wilberforce Road, Cambridge, CB3 0WA (United Kingdom)
2016-03-25
We present the universal one-loop effective action for all operators of dimension up to six obtained by integrating out massive, non-degenerate multiplets. Our general expression may be applied to loops of heavy fermions or bosons, and has been checked against partial results available in the literature. The broad applicability of this approach simplifies one-loop matching from an ultraviolet model to a lower-energy effective field theory (EFT), a procedure which is now reduced to the evaluation of a combination of matrices in our universal expression, without any loop integrals to evaluate. We illustrate the relationship of our results to the Standard Model (SM) EFT, using as an example the supersymmetric stop and sbottom squark Lagrangian and extracting from our universal expression the Wilson coefficients of dimension-six operators composed of SM fields.
The Universal One-Loop Effective Action
Drozd, Aleksandra; Quevillon, Jérémie; You, Tevong
2016-01-01
We present the universal one-loop effective action for all operators of dimension up to six obtained by integrating out massive, non-degenerate multiplets. Our general expression may be applied to loops of heavy fermions or bosons, and has been checked against partial results available in the literature. The broad applicability of this approach simplifies one-loop matching from an ultraviolet model to a lower-energy effective field theory (EFT), a procedure which is now reduced to the evaluation of a combination of matrices in our universal expression, without any loop integrals to evaluate. We illustrate the relationship of our results to the Standard Model (SM) EFT, using as an example the supersymmetric stop and sbottom squark Lagrangian and extracting from our universal expression the Wilson coefficients of dimension-six operators composed of SM fields.
The universal one-loop effective action
Drozd, Aleksandra; Ellis, John; Quevillon, Jérémie; You, Tevong
2016-03-01
We present the universal one-loop effective action for all operators of dimension up to six obtained by integrating out massive, non-degenerate multiplets. Our general expression may be applied to loops of heavy fermions or bosons, and has been checked against partial results available in the literature. The broad applicability of this approach simplifies one-loop matching from an ultraviolet model to a lower-energy effective field theory (EFT), a procedure which is now reduced to the evaluation of a combination of matrices in our universal expression, without any loop integrals to evaluate. We illustrate the relationship of our results to the Standard Model (SM) EFT, using as an example the supersymmetric stop and sbottom squark Lagrangian and extracting from our universal expression the Wilson coefficients of dimension-six operators composed of SM fields.
The universal one-loop effective action
International Nuclear Information System (INIS)
Drozd, Aleksandra; Ellis, John; Quevillon, Jérémie; You, Tevong
2016-01-01
We present the universal one-loop effective action for all operators of dimension up to six obtained by integrating out massive, non-degenerate multiplets. Our general expression may be applied to loops of heavy fermions or bosons, and has been checked against partial results available in the literature. The broad applicability of this approach simplifies one-loop matching from an ultraviolet model to a lower-energy effective field theory (EFT), a procedure which is now reduced to the evaluation of a combination of matrices in our universal expression, without any loop integrals to evaluate. We illustrate the relationship of our results to the Standard Model (SM) EFT, using as an example the supersymmetric stop and sbottom squark Lagrangian and extracting from our universal expression the Wilson coefficients of dimension-six operators composed of SM fields.
Wilson Dslash Kernel From Lattice QCD Optimization
Energy Technology Data Exchange (ETDEWEB)
Joo, Balint [Jefferson Lab, Newport News, VA; Smelyanskiy, Mikhail [Parallel Computing Lab, Intel Corporation, California, USA; Kalamkar, Dhiraj D. [Parallel Computing Lab, Intel Corporation, India; Vaidyanathan, Karthikeyan [Parallel Computing Lab, Intel Corporation, India
2015-07-01
Lattice Quantum Chromodynamics (LQCD) is a numerical technique used for calculations in Theoretical Nuclear and High Energy Physics. LQCD is traditionally one of the first applications ported to many new high performance computing architectures and indeed LQCD practitioners have been known to design and build custom LQCD computers. Lattice QCD kernels are frequently used as benchmarks (e.g. 168.wupwise in the SPEC suite) and are generally well understood, and as such are ideal to illustrate several optimization techniques. In this chapter we will detail our work in optimizing the Wilson-Dslash kernels for Intel Xeon Phi, however, as we will show the technique gives excellent performance on regular Xeon Architecture as well.
On Wilson bases in $L^2(\\mathbb{R}^d)$
DEFF Research Database (Denmark)
Bownik, Marcin; Sielemann Jakobsen, Mads; Lemvig, Jakob
2017-01-01
A Wilson system is a collection of finite linear combinations of time frequency shifts of a square integrable function. It is well known that, starting from a tight Gabor frame for $L^{2}(\\mathbb{R})$ with redundancy 2, one can construct an orthonormal Wilson basis for $L^2(\\mathbb{R})$ whose...... generator is well localized in the time-frequency plane. In this paper we use the fact that a Wilson system is a shift-invariant system to explore its relationship with Gabor systems. Specifically, we show that one can construct $d$-dimensional orthonormal Wilson bases starting from tight Gabor frames...... of redundancy $2^k$, where $k=1, 2, \\hdots, d$. These results generalize most of the known results about the existence of orthonormal Wilson bases....
Neuromuscular Electrical Stimulation Therapy for Dysphagia Caused by Wilson's Disease
Lee, Seon Yeong; Yang, Hee Seung; Lee, Seung Hwa; Jeung, Hae Won; Park, Young Ok
2012-01-01
Wilson's disease is an autosomal recessive disorder of abnormal copper metabolism. Although dysphagia is a common complaint of patients with Wilson's disease and pneumonia is an important cause of death in these patients, management of swallowing function has rarely been reported in the context of Wilson's disease. Hence, we report a case of Wilson's disease presenting with dysphagia. A 33-year-old man visited our hospital with a complaint of difficulty in swallowing, since about last 7 years and which had worsened since the last 2-3 months. He was diagnosed with Wilson's disease about 13 years ago. On the initial VFSS, reduced hyoid bone movement, impaired epiglottic movement and moderate amount of residue in the valleculae during the pharyngeal phase were noted. After 10 sessions of neuromuscular electrical stimulation for 1 hour per day, decreased amount of residue was observed in the valleculae during the pharyngeal phase on the follow-up VFSS. PMID:22837979
Conformal primaries of $OSp(8/4,R)$ and BPS states in $AdS_{4}$
Ferrara, Sergio; Ferrara, Sergio; Sokatchev, Emery
2000-01-01
We derive short UIR's of the OSp(8/4,R) superalgebra of 3d N=8 superconformalfield theories by the requirement that the highest weight states areannihilated by a subset of the super-Poincare odd generators. We then find asuperfield realization of these BPS saturated UIR's as "composite operators" ofthe two basic ultrashort "supersingleton" multiplets. These representations arethe AdS4 analogue of BPS states preserving different fractions of supersymmetryand are therefore suitable to classify perturbative and non-perturbativeexcitations of M-theory compactifications.
Członkowska, Anna; Tarnacka, Beata; Möller, Jens Carsten; Leinweber, Barbara; Bandmann, Oliver; Woimant, France; Oertel, Wolfgang H
2007-01-01
The clinical forms of Wilson's disease (WD) neurological manifestations can be divided into three movement disorder syndromes: a) dystonic, b) ataxic, c) parkinsonian syndrome. These syndromes in WD seldom occur in isolation. Clinical rating scales such as the Unified Parkinson;s Disease Rating Scale (UPDRS), the International Cooperative Ataxia Rating Scale (ICARS) and the Rating Scale for Dystonia (RSD), focusing on either parkinsonism or ataxia or dystonia alone, are not sufficient to reflect accurately the motor impairment of WD patients. The aim of the study was to develop a novel rating scale for WD, because as far as we know no scale for the clinical rating in WD has been designed before. In 2004 the EuroWilson consortium was founded, to create a European WD database. Members of the consortium from Poland, Germany, and France prepared a new scale using clinical rating scales as the UPDRS, ICARS, and RSD. Prepared drafts were discussed several times in detail at the first international neurological EuroWilson meeting in September 2004 in Paris and in November in Warsaw. The novel scale for WD consists of 3 parts, including: consciousness, a historical review based on the Barthel scale (2-11 items), and neurological examination (12-35, items). The maximum score for the first part is 3, for the second 39 points, and for the last 143 points. The initial reliability of the scale on the basis of 6 patients (on DVD) and 8 investigators was assessed. Inter-rater agreement was high. Now the scale is used by the EuroWilson and GeNeMove consortia.
D-instanton and polyinstanton effects from type I' D0-brane loops
Petersson, Christoffer; Uranga, Angel M
2010-01-01
We study non-perturbative D(-1)-instanton corrections to quartic gauge and curvature couplings in 8d type IIB orientifolds, in terms of a one-loop computation of BPS D0-branes in T-dual type I' models. The complete perturbative and non-perturbative results are determined by the BPS multiplicities of perturbative open strings and D0-brane bound states in the 9d type I' theory. Its modular properties admit a geometric interpretation by lifting to Horava-Witten theory. We use the type I' viewpoint to motivate a proper interpretation of 8d and 4d polyinstanton effects, consistent with heterotic - type II orientifold duality.
Multi-centered N=2 BPS black holes: a double copy description
Energy Technology Data Exchange (ETDEWEB)
Cardoso, G.L.; Nagy, S.; Nampuri, S. [Center for Mathematical Analysis, Geometry and Dynamical Systems,Department of Mathematics, Instituto Superior Técnico, Universidade de Lisboa,Av. Rovisco Pais, Lisboa, 1049-001 (Portugal)
2017-04-07
We present the on-shell double copy dictionary for linearised N=2 supergravity coupled to an arbitrary number of vector multiplets in four dimensions. Subsequently, we use it to construct a double copy description of multi-centered BPS black hole solutions in these theories in the weak-field approximation.
Domain Walls, near-BPS Bubbles and Probabilities in the Landscape
Energy Technology Data Exchange (ETDEWEB)
Ceresole, Anna; /INFN, Turin /Turin U.; Dall' Agata, Gianguido; /CERN; Giryavets, Alexander; Kallosh, Renata; Linde, Andrei; /Stanford U., Phys. Dept.
2006-06-27
We develop a theory of static BPS domain walls in stringy landscape and present a large family of BPS walls interpolating between different supersymmetric vacua. Examples include KKLT models, STU models, type IIB multiple flux vacua, and models with several Minkowski and AdS vacua. After the uplifting, some of the vacua become dS, whereas some others remain AdS. The near-BPS walls separating these vacua may be seen as bubble walls in the theory of vacuum decay. As an outcome of our investigation of the BPS walls, we found that the decay rate of dS vacua to a collapsing space with a negative vacuum energy can be quite large. The parts of space that experience a decay to a collapsing space, or to a Minkowski vacuum, never return back to dS space. The channels of irreversible vacuum decay serve as sinks for the probability flow. The existence of such sinks is a distinguishing feature of the landscape. We show that it strongly affects the probability distributions in string cosmology.
Loop equation in Lattice gauge theories and bootstrap methods
Directory of Open Access Journals (Sweden)
Anderson Peter
2018-01-01
Full Text Available In principle the loop equation provides a complete formulation of a gauge theory purely in terms ofWilson loops. In the case of lattice gauge theories the loop equation is a well defined equation for a discrete set of quantities and can be easily solved at strong coupling either numerically or by series expansion. At weak coupling, however, we argue that the equations are not well defined unless a certain set of positivity constraints is imposed. Using semi-definite programming we show numerically that, for a pure Yang Mills theory in two, three and four dimensions, these constraints lead to good results for the mean value of the energy at weak coupling. Further, the positivity constraints imply the existence of a positive definite matrix whose entries are expectation values of Wilson loops. This matrix allows us to define a certain entropy associated with theWilson loops. We compute this entropy numerically and describe some of its properties. Finally we discuss some preliminary ideas for extending the results to supersymmetric N = 4 SYM.
[Wilson disease - factors affecting clinical presentation].
Litwin, Tomasz; Członkowska, Anna
2013-01-01
Wilson disease (WD) is a genetic disorder with copper metabolism disturbances leading to copper accumulation in many organs with their secondary damage. It is caused by mutation in the ATP7B gene on chromosome 13, which encodes ATP-ase 7B involved in copper transport. The age of neurologic symptom onset in WD is 20-30 years, but there is a wide spectrum of disease including: age at onset, clinical signs and treatment efficacy. More than 500 mutations of ATP7B have been described so far, but the WD genotype does not explain the disease variability. Several other factors are suspected to influence WD presentation, including polymorphisms in the genes encoding: apolipoprotein E, prion-related protein, methyltenetetrahydrofolate reductase, Murr1, antioxidant-1, X-linked inhibitor of apoptosis as well as iron metabolism disturbances, gender impact, inflammatory reactions and oxidative stress. The explanation of their significance can change the therapy of WD. The aim of our study was to review and assess the clinical significance of the factors affecting WD presentation.
Quality of life in Wilson's disease
Komal Kumar, R. N.; Taly, A. B.; Nair, K. P. S.; Sinha, S.; Prashanth, L. K.; Vidya, N.; Arunodaya, G. R.; Rao, S.
2008-01-01
Background: Assessment of Quality of life (QoL) is fast assuming significance as the measure of health in many disorders. Aim: To correlate clinical severity and QoL in patients with Wilson's disease (WD). Materials and Methods: We evaluated patients of WD on regular follow up for at least two years and aged over 18 years using Neurological Symptom Score (NSS) for clinical severity and WHO-BREF for QoL at a university teaching hospital. Patients with inability to respond to the questionnaire due to behavioral problems, low IQ or other disease related factors were excluded. These 30 patients (M:F:: 23:7) had a mean age of 27.97 ± 11.16 years at evaluation and the mean duration of treatment of 9.2 ± 6.4 years. Results: All four domains of WHO-QoL-BREF viz., Physical, Psychological, Social and Environmental correlated well with each other (p neurological assessment and should be routinely incorporated in the evaluation of outcome of patients with WD and other chronic neurological disorders. PMID:19966977
On the loop-loop scattering amplitudes in Abelian and non-Abelian gauge theories
Energy Technology Data Exchange (ETDEWEB)
Meggiolaro, Enrico [Dipartimento di Fisica, Universita di Pisa, Largo Pontecorvo 3, I-56127 Pisa (Italy)]. E-mail: enrico.meggiolaro@df.unipi.it
2005-02-14
The high-energy elastic scattering amplitude of two colour-singlet qq-bar pairs is governed by the correlation function of two Wilson loops, which follow the classical straight lines for quark (antiquark) trajectories. This quantity is expected to be free of IR divergences, differently from what happens for the parton-parton elastic scattering amplitude, described, in the high-energy limit, by the expectation value of two Wilson lines. We shall explicitly test this IR finiteness by a direct non-perturbative computation of the loop-loop scattering amplitudes in the (pedagogic, but surely physically interesting) case of quenched QED. The results obtained for the Abelian case will be generalized to the case of a non-Abelian gauge theory with Nc colours, but stopping to the order O(g4) in perturbation theory. In connection with the above-mentioned IR finiteness, we shall also discuss some analytic properties of the loop-loop scattering amplitudes in both Abelian and non-Abelian gauge theories, when going from Minkowskian to Euclidean theory, which can be relevant to the still unsolved problem of the s-dependence of hadron-hadron total cross-sections.
Obituary: Peter Robert Wilson, 1929-2007
Snodgrass, Herschel B.
2009-01-01
It is with great sadness that I report the passing of Peter Robert Wilson, a well-known and well-loved figure in the solar physics community. Peter was on the faculty of the Department of Applied Mathematics at the University of Sydney for 39 years, and Chair of the department for 24 of these years. He was the author or co-author of more than 80 scientific research papers and a book, Solar and Stellar Activity Cycles (1994), published by Cambridge University Press. He died suddenly of a heart attack, at his home in Glebe, Australia, in the early morning of 11 November 2007. Peter was an organizer of, and participant in, many international conferences and workshops. He traveled extensively, holding visiting appointments at the University of Colorado (JILA), at Cambridge University, at the College de France (Paris), and at the California Institute of Technology [CalTech]. Most of his work was in the field of solar physics, but he also did some work on the philosophy of science and on tides. Peter came from a line of mathematicians. His father, Robert Wilson, immigrated to Australia from Glasgow in 1911, and became a mathematics teacher at Scotch College, a private school in Melbourne. There his name was changed to 'Bill' because 'Bob' was already taken." Peter's enjoyment of this story as characteristic of Australian academia (as any fan of Monty Python would understand) is indicative of his infectious sense of humor. In a similar vein, he claimed ancestry traced back to the eighteenth-century Scottish mathematician Alexander Wilson, Professor of Astronomy at the University of Glasgow. That Wilson is famous in the solar physics community for his discovery, known as the "Wilson Effect," of the photospheric depressions associated with sunspots. Peter himself could not resist writing a paper on this subject, and was delighted when the bait was taken by some less-informed colleagues who chided him for "naming an effect after himself." "Bill" Wilson married Naomi
Open spin chains in super Yang-Mills at higher loops: some potential problems with integrability
International Nuclear Information System (INIS)
Agarwal, Abhishek
2006-01-01
The super Yang-Mills duals of open strings attached to maximal giant gravitons are studied in perturbation theory. It is shown that non-BPS baryonic excitations of the gauge theory can be studied within the paradigm of open quantum spin chains even beyond the leading order in perturbation theory. The open spin chain describing the two loop mixing of non-BPS giant gravitons charged under an su(2) of the so(6) R symmetry group is explicitly constructed. It is also shown that although the corresponding open spin chain is integrable at the one loop order, there is a potential breakdown of integrability at two and higher loops. The study of integrability is performed using coordinate Bethe ansatz techniques
Uncovering the triple omeron vertex from Wilson line formalism
International Nuclear Information System (INIS)
Chirilli, G. A.; Szymanowski, L.; Wallon, S.
2011-01-01
We compute the triple omeron vertex from the Wilson line formalism, including both planar and nonplanar contributions, and get perfect agreement with the result obtained in the Extended Generalized Logarithmic Approximation based on Reggeon calculus.
Trivializing maps, the Wilson flow and the HMC algorithm
Lüscher, Martin
2010-01-01
In lattice gauge theory, there exist field transformations that map the theory to the trivial one, where the basic field variables are completely decoupled from one another. Such maps can be constructed systematically by integrating certain flow equations in field space. The construction is worked out in some detail and it is proposed to combine the Wilson flow (which generates approximately trivializing maps for the Wilson gauge action) with the HMC simulation algorithm in order to improve the efficiency of lattice QCD simulations.
Taking Charge: Walter Sydney Adams and the Mount Wilson Observatory
Brashear, R.
2004-12-01
The growing preeminence of American observational astronomy in the first half of the 20th century is a well-known story and much credit is given to George Ellery Hale and his skill as an observatory-building entrepreneur. But a key figure who has yet to be discussed in great detail is Walter Sydney Adams (1876-1956), Hale's Assistant Director at Mount Wilson Observatory. Due to Hale's illnesses, Adams was Acting Director for much of Hale's tenure, and he became the second Director of Mount Wilson from 1923 to 1946. Behind his New England reserve Adams was instrumental in the growth of Mount Wilson and thus American astronomy in general. Adams was hand-picked by Hale to take charge of stellar spectroscopy work at Yerkes and Mount Wilson and the younger astronomer showed tremendous loyalty to Hale and Hale's vision throughout his career. As Adams assumed the leadership role at Mount Wilson he concentrated on making the observatory a place where researchers worked with great freedom but maintain a high level of cooperation. This paper will concentrate on Adams's early years and look at his growing relationship with Hale and how he came to be the central figure in the early history of Mount Wilson as both a solar and stellar observatory. His education, his years at Dartmouth and Yerkes (including his unfortunate encounter with epsilon Leonis), and his formative years on Mount Wilson are all important in learning how he shaped the direction of Mount Wilson and the development of American astronomy in the first half of the 20th century. This latter history cannot be complete until we bring Adams into better focus.
The cerebral lesions of Wilson's disease on computer tomography
International Nuclear Information System (INIS)
Rodiek, S.
1983-01-01
M. Wilson is often being mistaken as such for several years and kept for psychosis or another extrapyramidal disease. When the disease causes neuro-psychiatric symptoms a certain part of cases shows typical lesions in CT mainly affecting the Nucleus lentiformis and frontal cortex. From our own material two cases of M. Wilson are shown and compared with two other cases with identical patterns of lesions following toxic and hypoxic brain damage. (orig.) [de
Cranial MR findings in Wilson's disease
International Nuclear Information System (INIS)
Saatci, I.; Topcu, M.; Baltaoglu, F.F.; Koese, G.; Yalaz, K.; Renda, Y.; Besim, A.
1997-01-01
Purpose: To define various cranial MR appearances in Wilson's disease (WD). Material and Methods: MR examinations of 30 patients (9-44 years old) with WD were retrospectively reviewed. Six patients were asymptomatic siblings. Three other patients had isolated hepatic involvement, one with no symptoms. The remaining 21 patients had neurological involvement, 7 of whom had the mixed form of the disease. Nine patients had hepatic dysfunction, the 3 with isolated hepatic involvement and 6 of the 7 with the mixed form. Results: All symptomatic patients (n=23) had abnormal MR examinations. Atrophy was present in the majority of them. The most frequently involved sites were putamen (18/21) and pons (18/21) in patients with neurological abnormality. The putaminal lesions showed a consistent pattern of symmetric, bilateral, concentric-laminar T2 hyperintensity. Putaminal lesions were lacking in only 3 patients with neurological involvement, all of whom were relatively old and had had the disease for a longer duration. Most of the patients with hepatic dysfunction (8/9) had increased T1 signal intensity in the basal ganglia, particularly in the globus pallidus. Pontine involvement always included the dorsal aspect of the pons, however, in some cases the central portion of pons was also affected but ventrolateral longitudinal fibers were spared. Midbrain (16/21), thalamic (10/21) and caudate nucleus lesions (9/21) were also encountered. In a few patients cortical and subcortical white matter lesions were present with a predilection to the frontal lobe, particularly the precentral region. In one patient, a hemorrhagic focus was identified within the white matter lesion. (orig./VHE)
Loop equations and bootstrap methods in the lattice
Directory of Open Access Journals (Sweden)
Peter D. Anderson
2017-08-01
Full Text Available Pure gauge theories can be formulated in terms of Wilson Loops by means of the loop equation. In the large-N limit this equation closes in the expectation value of single loops. In particular, using the lattice as a regulator, it becomes a well defined equation for a discrete set of loops. In this paper we study different numerical approaches to solving this equation. Previous ideas gave good results in the strong coupling region. Here we propose an alternative method based on the observation that certain matrices ρˆ of Wilson loop expectation values are positive definite. They also have unit trace (ρˆ⪰0,Trρˆ=1, in fact they can be defined as reduced density matrices in the space of open loops after tracing over color indices and can be used to define an entropy associated with the loss of information due to such trace SWL=−Tr[ρˆlnρˆ]. The condition that such matrices are positive definite allows us to study the weak coupling region which is relevant for the continuum limit. In the exactly solvable case of two dimensions this approach gives very good results by considering just a few loops. In four dimensions it gives good results in the weak coupling region and therefore is complementary to the strong coupling expansion. We compare the results with standard Monte Carlo simulations.
Anatomy of Two-Loop Effective Action in Noncommutative Field Theories
Kiem, Young-jai; Rey, Soo-Jong; Sato, Haru-Tada
2002-01-01
We compute, at two-loop order, one-particle-irreducible Green functions and effective action in noncommutative $\\lambda[\\Phi^3]_\\star$-theory for both planar (g=0, h=3) and nonplanar (g=1, h=1) contributions. We adopt worldline formulation of the Feynman diagrammatics so that relation to string theory diagrammatics is made transparent in the Seiberg-Witten limit. We argue that the resulting two-loop effective action is expressible via open Wilson lines: one-particle-irreducible effective action is generating functional of connected diagrams for interacting open Wilson lines.
Energy Technology Data Exchange (ETDEWEB)
Warne, Larry Kevin; Lucero, Larry Martin; Langston, William L.; Salazar, Robert Austin; Coleman, Phillip Dale; Basilio, Lorena I.; Bacon, Larry Donald
2012-05-01
This report estimates inductively-coupled energy to a low-impedance load in a loop-to-loop arrangement. Both analytical models and full-wave numerical simulations are used and the resulting fields, coupled powers and energies are compared. The energies are simply estimated from the coupled powers through approximations to the energy theorem. The transmitter loop is taken to be either a circular geometry or a rectangular-loop (stripline-type) geometry that was used in an experimental setup. Simple magnetic field models are constructed and used to estimate the mutual inductance to the receiving loop, which is taken to be circular with one or several turns. Circuit elements are estimated and used to determine the coupled current and power (an equivalent antenna picture is also given). These results are compared to an electromagnetic simulation of the transmitter geometry. Simple approximate relations are also given to estimate coupled energy from the power. The effect of additional loads in the form of attached leads, forming transmission lines, are considered. The results are summarized in a set of susceptibility-type curves. Finally, we also consider drives to the cables themselves and the resulting common-to-differential mode currents in the load.
Light-cone superspace BPS equations, and OSp(2, 2|16)
Hearin, Patrick
The BPS bound is formulated in light-cone superspace for the N = 4 superYang-Mills theory. As a consequence of the superalgebra all momenta are shown to be expressed as quadratic forms in the relevant supertransformations, and these forms are used to derive the light-cone superspace BPS equations. Finally, the superfield expressions are expanded out to component form, and the Wu-Yang Monopole boosted to the infinite momentum frame is shown to be a solution. A possible non-linear realization of the OSp(2, 2|16) superconformal algebra is prescribed with methods used to derive the OSp(2, 2|8) theory in light-cone superspace. This theory is shown to have an inconsistency in the dynamical constraints which cannot be resolved, and no non-linear field theory can be consistently realized. This inconsistency is derived in the covariant OSp(2, 2|16) theory.
Towards 4-point correlation functions of any (1/2)-BPS operators from supergravity
Energy Technology Data Exchange (ETDEWEB)
Arutyunov, Gleb [II. Institut für Theoretische Physik, Universität Hamburg,Luruper Chaussee 149, Hamburg, 22761 (Germany); Zentrum für Mathematische Physik, Universität Hamburg,Bundesstrasse 55, Hamburg, 20146 (Germany); Frolov, Sergey [Hamilton Mathematics Institute and School of Mathematics, Trinity College,Dublin 2 (Ireland); Klabbers, Rob; Savin, Sergei [II. Institut für Theoretische Physik, Universität Hamburg,Luruper Chaussee 149, Hamburg, 22761 (Germany); Zentrum für Mathematische Physik, Universität Hamburg,Bundesstrasse 55, Hamburg, 20146 (Germany)
2017-04-03
The quartic effective action for Kaluza-Klein modes that arises upon compactification of type IIB supergravity on the five-sphere S{sup 5} is a starting point for computing the four-point correlation functions of arbitrary weight (1/2)-BPS operators in N=4 super Yang-Mills theory in the supergravity approximation. The apparent structure of this action is rather involved, in particular it contains quartic terms with four derivatives which cannot be removed by field redefinitions. By exhibiting intricate identities between certain integrals involving spherical harmonics of S{sup 5} we show that the net contribution of these four-derivative terms to the effective action vanishes. Our result is in agreement with and provides further support to the recent conjecture on the Mellin space representation of the four-point correlation function of any (1/2)-BPS operators in the supergravity approximation.
Orbits of Exceptional Groups, Duality and BPS States in String Theory
Ferrara, Sergio; Ferrara, Sergio; Gunaydin, Murat
1998-01-01
We give an invariant classification of orbits of the fundamental representations of exceptional groups $E_{7(7)}$ and $E_{6(6)}$ which classify BPS states in string and M theories toroidally compactified to d=4 and 5. The exceptional Jordan algebra and the exceptional Freudenthal triple system and their cubic and quartic invariants play a major role in this classification. The cubic and quartic invariants correspond to the black hole entropy in d=5 and d=4, respectively. The classification of BPS states preserving different numbers of supersymmetries is in close parallel to the classification of the little groups and the orbits of timelike, lightlike and space-like vectors in Minkowski space.
The Hodge-Elliptic Genus, Spinning BPS States, and Black Holes
Kachru, Shamit; Tripathy, Arnav
2017-10-01
We perform a refined count of BPS states in the compactification of M-theory on {K3 × T^2}, keeping track of the information provided by both the {SU(2)_L} and {SU(2)_R} angular momenta in the SO(4) little group. Mathematically, this four variable counting function may be expressed via the motivic Donaldson-Thomas counts of {K3 × T^2}, simultaneously refining Katz, Klemm, and Pandharipande's motivic stable pairs counts on K3 and Oberdieck-Pandharipande's Gromov-Witten counts on {K3 × T^2}. This provides the first full answer for motivic curve counts of a compact Calabi-Yau threefold. Along the way, we develop a Hodge-elliptic genus for Calabi-Yau manifolds—a new counting function for BPS states that interpolates between the Hodge polynomial and the elliptic genus of a Calabi-Yau.
International Nuclear Information System (INIS)
Odake, Satoru; Sasaki, Ryu
2009-01-01
Two sets of infinitely many exceptional orthogonal polynomials related to the Wilson and Askey-Wilson polynomials are presented. They are derived as the eigenfunctions of shape invariant and thus exactly solvable quantum mechanical Hamiltonians, which are deformations of those for the Wilson and Askey-Wilson polynomials in terms of a degree l (l=1,2,...) eigenpolynomial. These polynomials are exceptional in the sense that they start from degree l≥1 and thus not constrained by any generalisation of Bochner's theorem.
W, Melyana N; Irmawati, Irmawati; Wijayati, Sugih
2012-01-01
The purpose of this study was to determine the effectiveness of the method of hypnosis, massage and relaxation endorphins to the intensity of pain during on the first stage of Normal Delivery in BPS (Private Practice Midwives) Semarang City area. The research method used was non-equivalent experimental design, a sample of 20 mothers maternity on each - each treatment group. Test used was ANOVA test followed Post Hock Tukey test. These results obtained p-value = 0.001 (significant) followed po...
Dissecting zero modes and bound states on BPS vortices in Ginzburg-Landau superconductors
International Nuclear Information System (INIS)
Izquierdo, A. Alonso; Fuertes, W. Garcia; Guilarte, J. Mateos
2016-01-01
In this paper the zero modes of fluctuation of cylindrically symmetric self-dual vortices are analyzed and described in full detail. These BPS topological defects arise at the critical point between Type II and Type I superconductors, or, equivalently, when the masses of the Higgs particle and the vector boson in the Abelian Higgs model are equal. In addition, novel bound states of Higss and vector bosons trapped by the self-dual vortices at their core are found and investigated.
Dissecting zero modes and bound states on BPS vortices in Ginzburg-Landau superconductors
Energy Technology Data Exchange (ETDEWEB)
Izquierdo, A. Alonso [Departamento de Matematica Aplicada, Universidad de Salamanca,Facultad de Ciencias Agrarias y Ambientales,Av. Filiberto Villalobos 119, E-37008 Salamanca (Spain); Fuertes, W. Garcia [Departamento de Fisica, Universidad de Oviedo, Facultad de Ciencias,Calle Calvo Sotelo s/n, E-33007 Oviedo (Spain); Guilarte, J. Mateos [Departamento de Fisica Fundamental, Universidad de Salamanca, Facultad de Ciencias,Plaza de la Merced, E-37008 Salamanca (Spain)
2016-05-12
In this paper the zero modes of fluctuation of cylindrically symmetric self-dual vortices are analyzed and described in full detail. These BPS topological defects arise at the critical point between Type II and Type I superconductors, or, equivalently, when the masses of the Higgs particle and the vector boson in the Abelian Higgs model are equal. In addition, novel bound states of Higss and vector bosons trapped by the self-dual vortices at their core are found and investigated.
Black branes in AdS: BPS bounds and asymptotic charges
Energy Technology Data Exchange (ETDEWEB)
Hristov, K. [Institute for Theoretical Physics and Spinoza Institute, Utrecht University, 3508 TD Utrecht (Netherlands); Faculty of Physics, Sofia University, Sofia 1164 (Bulgaria); Toldo, C.; Vandoren, S. [Institute for Theoretical Physics and Spinoza Institute, Utrecht University, 3508 TD Utrecht (Netherlands)
2012-09-15
We focus on black branes and toroidal black holes in N = 2 gauged supergravities that asymptote to AdS{sub 4}, and derive formulas for the mass and central charge densities. We derive the corresponding BPS bound from the superalgebra of the asymptotic vacuum and illustrate our procedure with explicit examples of genuine black brane solutions with non-trivial scalars. (Copyright copyright 2012 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)
Exact half-BPS type IIB interface solutions I: local solution and supersymmetric Janus
Energy Technology Data Exchange (ETDEWEB)
D' Hoker, Eric; Estes, John; Gutperle, Michael [Department of Physics and Astronomy, University of California, Los Angeles, CA 90095 (United States)
2007-06-15
The complete Type IIB supergravity solutions with 16 supersymmetries are obtained on the manifold AdS{sub 4} x S{sup 2} x S{sup 2} x {sigma} with SO(2, 3) x SO(3) x SO(3) symmetry in terms of two holomorphic functions on a Riemann surface {sigma}, which generally has a boundary. This is achieved by reducing the BPS equations using the above symmetry requirements, proving that all solutions of the BPS equations solve the full Type IIB supergravity field equations, mapping the BPS equations onto a new integrable system akin to the Liouville and Sine-Gordon theories, and mapping this integrable system to a linear equation which can be solved exactly. Amongst the infinite class of solutions, a non-singular Janus solution is identified which provides the AdS/CFT dual of the maximally supersymmetric Yang-Mills interface theory discovered recently. The construction of general classes of globally non-singular solutions, including fully back-reacted AdS{sub 5} x S{sup 5} and supersymmetric Janus doped with D5 and/or NS5 branes, is deferred to a companion paper.
arXiv Wilson lines and UV sensitivity in magnetic compactifications
Ghilencea, D.M.
2017-06-07
We investigate the ultraviolet (UV) behaviour of 6D N=1 supersymmetric effective (Abelian) gauge theories compactified on a two-torus (T$_{2}$) with magnetic flux. To this purpose we compute offshell the one-loop correction to the Wilson line state self-energy. The offshell calculation is actually necessary to capture the usual effective field theory expansion in powers of (∂/Λ). Particular care is paid to the regularization of the (divergent) momentum integrals, which is relevant for identifying the corresponding counterterm(s). We find a counterterm which is a new higher dimensional effective operator of dimension d=6, that is enhanced for a larger compactification area (where the effective theory applies) and is consistent with the symmetries of the theory. Its consequences are briefly discussed and comparison is made with orbifold compactifications without flux.
Obituary: Andrew Stephen Wilson, 1947-2008
Veilleux, Sylvain
2009-01-01
On 24 May 2008, Andrew Stephen Wilson passed away at the age of 61, in his home in Silver Spring, Maryland, from complications resulting from a painful spinal illness. Andrew was arguably one of the first truly multi-wavelength astronomers of his generation. His scientific work on active galactic nuclei [AGN] spanned the entire electromagnetic spectrum from the radio to the X-rays. Andrew was born in Doncaster, Yorkshire, England, on 26 March 1947. He was the younger of two brothers whose births were separated by the Second World War. His father, Norman, came from a relatively affluent family who were coal merchants. His mother, Mary, came from a less comfortable background, one of seven children, daughter of a skilled cabinet maker/French polisher, who went through a very hard time during the depression. As a teacher, she placed enormous value on hard work and education as a way of gaining advancement in life. When Andrew was four, the family moved to Skipton, a nice market town in the Yorkshire dales. Andrew went to a small village school until age eleven when he entered Ermysted's Grammar School. He was an enthusiastic soccer and cricket player. He never lost his enthusiasm for soccer and supported the local soccer team, Leeds United, for all his life. Andrew also followed the Yorkshire county cricket team. Andrew's interest in astronomy stemmed from the fact that at Ermysted's Grammar School someone donated a four-inch refracting telescope, so he and his friends used to go back in the evenings to investigate the rings of Saturn, the moons of Jupiter, and various nebulae. While an undergraduate at Cambridge, Andrew joined the astronomy club and ground an 8-inch mirror by hand as a part of a telescope that he set up in the backyard of his parents' house. Andrew spent hours observing with this telescope, and it was the wonder of the family. At Cambridge, Andrew obtained his bachelor's degree with first-class honors in 1969. During a short visit in London with his
Non-BPS exact solutions and their relation to bions in ℂP{sup N−1} models
Energy Technology Data Exchange (ETDEWEB)
Misumi, Tatsuhiro [Department of Mathematical Science, Akita University,1-1 Tegata Gakuen-machi, Akita 010-8502 (Japan); Research and Education Center for Natural Sciences, Keio University,4-1-1 Hiyoshi, Yokohama, Kanagawa 223-8521 (Japan); Nitta, Muneto; Sakai, Norisuke [Department of Physics and Research and Education Center for Natural Sciences, Keio University,4-1-1 Hiyoshi, Yokohama, Kanagawa 223-8521 (Japan)
2016-05-10
We investigate non-BPS exact solutions in ℂP{sup N−1} sigma models on ℝ{sup 1}×S{sup 1} with twisted boundary conditions, by using the Din-Zakrzewski projection method. We focus on the relation of the non-BPS solutions to the ansatz of multi-instanton (bion) configurations and discuss their significance in the context of the resurgence theory. We find that the transition between seemingly distinct configurations of multi-instantons occur as moduli changes in the non-BPS solutions, and the simplest non-BPS exact solution corresponds to multi-bion configurations with fully-compressed double fractional instantons in the middle. It indicates that the non-BPS solutions make small but nonzero contribution to the resurgent trans-series as special cases of the multi-bion configurations. We observe a generic pattern of transitions between distinct multi-bion configurations (flipping partners), leading to the three essential properties of the non-BPS exact solution: (i) opposite sign for terms corresponding to the left and right infinities, (ii) symmetric location of fractional instantons, and (iii) the transition between distinct bion configurations. By studying the balance of forces, we show that the relative phases between the instanton constituents play decisive roles in stability and instability of the muli-instanton configurations. We discuss local and global instabilities of the solutions such as negative modes and the flow to the other saddle points, by considering the deformations of the non-BPS exact solutions within our multi-instanton ansatz. We also briefly discuss some classes of the non-BPS exact solutions in Grassmann sigma models.
BPS state counting using wall-crossing, holomorphic anomalies and modularity
International Nuclear Information System (INIS)
Wotschke, Thomas
2013-05-01
In this thesis we examine the counting of BPS states using wall-crossing, holomorphic anomalies and modularity. We count BPS states that arise in two setups: multiple M5-branes wrapping P x T 2 , where P denotes a divisor inside a Calabi-Yau threefold and topological string theory on elliptic Calabi-Yau threefolds. The first setup has a dual description as type IIA string theory via a D4-D2-D0 brane system. Furthermore it leads to two descriptions depending on the size of P and T 2 relative to each other. For the case of a small divisor P this setup is described by the (0,4) Maldacena-Strominger-Witten conformal field theory of a black hole in M-theory and for the case of small T 2 the setup can by described by N=4 topological Yang-Mills theory on P. The BPS states are counted by the modified elliptic genus, which can be decomposed into a vector-valued modular form that provides the generating function for the BPS invariants and a Siegel-Narain theta function. In the first part we discuss the holomorphic anomaly of the modified elliptic genus for the case of two M5-branes and divisors with b + 2 (P)=1. Due to the wall-crossing effect the change in the generating function is captured by an indefinite theta function, which is a mock modular form. We use the Kontsevich-Soibelman wall-crossing formula to determine the jumps in the modified elliptic genus. Using the regularisation procedure for mock modular forms of Zwegers, modularity can be restored at the cost of holomorphicity. We show that the non-holomorphic completion is due to bound states of single M5-branes. At the attractor point in the moduli space we prove the holomorphic anomaly equation, which is compatible with the holomorphic anomaly equations observed in the context of N=4 Yang-Mills theory on P 2 and E-strings on a del Pezzo surface. We calculate the generating functions of BPS invariants for the divisors P 2 , F 0 , F 1 and the del Pezzo surface dP 8 and dP 9 ((1)/(2) K3). In the second part we study
BPS state counting using wall-crossing, holomorphic anomalies and modularity
Energy Technology Data Exchange (ETDEWEB)
Wotschke, Thomas
2013-05-15
In this thesis we examine the counting of BPS states using wall-crossing, holomorphic anomalies and modularity. We count BPS states that arise in two setups: multiple M5-branes wrapping P x T{sup 2}, where P denotes a divisor inside a Calabi-Yau threefold and topological string theory on elliptic Calabi-Yau threefolds. The first setup has a dual description as type IIA string theory via a D4-D2-D0 brane system. Furthermore it leads to two descriptions depending on the size of P and T{sup 2} relative to each other. For the case of a small divisor P this setup is described by the (0,4) Maldacena-Strominger-Witten conformal field theory of a black hole in M-theory and for the case of small T{sup 2} the setup can by described by N=4 topological Yang-Mills theory on P. The BPS states are counted by the modified elliptic genus, which can be decomposed into a vector-valued modular form that provides the generating function for the BPS invariants and a Siegel-Narain theta function. In the first part we discuss the holomorphic anomaly of the modified elliptic genus for the case of two M5-branes and divisors with b{sup +}{sub 2}(P)=1. Due to the wall-crossing effect the change in the generating function is captured by an indefinite theta function, which is a mock modular form. We use the Kontsevich-Soibelman wall-crossing formula to determine the jumps in the modified elliptic genus. Using the regularisation procedure for mock modular forms of Zwegers, modularity can be restored at the cost of holomorphicity. We show that the non-holomorphic completion is due to bound states of single M5-branes. At the attractor point in the moduli space we prove the holomorphic anomaly equation, which is compatible with the holomorphic anomaly equations observed in the context of N=4 Yang-Mills theory on P{sup 2} and E-strings on a del Pezzo surface. We calculate the generating functions of BPS invariants for the divisors P{sup 2}, F{sub 0}, F{sub 1} and the del Pezzo surface dP{sub 8} and
Calculating corrections in F-theory from refined BPS invariants and backreacted geometries
Energy Technology Data Exchange (ETDEWEB)
Poretschkin, Maximilian
2015-07-01
This thesis presents various corrections to F-theory compactifications which rely on the computation of refined Bogomol'nyi-Prasad-Sommerfield (BPS) invariants and the analysis of backreacted geometries. Detailed information about rigid supersymmetric theories in five dimensions is contained in an index counting refined BPS invariants. These BPS states fall into representations of SU(2){sub L} x SU(2){sub R}, the little group in five dimensions, which has an induced action on the cohomology of the moduli space of stable pairs. In the first part of this thesis, we present the computation of refined BPS state multiplicities associated to M-theory compactifications on local Calabi-Yau manifolds whose base is given by a del Pezzo or half K3 surface. For geometries with a toric realization we use an algorithm which is based on the Weierstrass normal form of the mirror geometry. In addition we use the refined holomorphic anomaly equation and the gap condition at the conifold locus in the moduli space in order to perform the direct integration and to fix the holomorphic ambiguity. In a second approach, we use the refined Goettsche formula and the refined modular anomaly equation that govern the (refined) genus expansion of the free energy of the half K3 surface. By this procedure, we compute the refined BPS invariants of the half K3 from which the results of the remaining del Pezzo surfaces are obtained by flop transitions and blow-downs. These calculations also make use of the high symmetry of the del Pezzo surfaces whose homology lattice contains the root lattice of exceptional Lie algebras. In cases where both approaches are applicable, we successfully check the compatibility of these two methods. In the second part of this thesis, we apply the results obtained from the calculation of the refined invariants of the del Pezzo respectively the half K3 surfaces to count non-perturbative objects in F-theory. The first application is given by BPS states of the E
Clinical presentation and mutations in Danish patients with Wilson disease
DEFF Research Database (Denmark)
Møller, Lisbeth Birk; Horn, Nina; Jeppesen, Tina Dysgaard
2011-01-01
This study describes the clinical presentation and diagnosis in all Danish patients (49, 41 unrelated) with Wilson disease (WND). On the basis of the number of diagnosed patients from 1990-2008, the prevalence was estimated to be 1:49 500. Among routinely used diagnostic tests, none were consiste......This study describes the clinical presentation and diagnosis in all Danish patients (49, 41 unrelated) with Wilson disease (WND). On the basis of the number of diagnosed patients from 1990-2008, the prevalence was estimated to be 1:49 500. Among routinely used diagnostic tests, none were....../27 mutations as either severe (age of onset 20 years), and correctly predicted the age of onset in 37/39 patients. This method should be tested in other Wilson populations....
Clinical presentation and mutations in Danish patients with Wilson disease
DEFF Research Database (Denmark)
Møller, Lisbeth Birk; Horn, Nina; Jeppesen, Tina Dysgaard
2011-01-01
This study describes the clinical presentation and diagnosis in all Danish patients (49, 41 unrelated) with Wilson disease (WND). On the basis of the number of diagnosed patients from 1990-2008, the prevalence was estimated to be 1:49¿500. Among routinely used diagnostic tests, none were consiste......This study describes the clinical presentation and diagnosis in all Danish patients (49, 41 unrelated) with Wilson disease (WND). On the basis of the number of diagnosed patients from 1990-2008, the prevalence was estimated to be 1:49¿500. Among routinely used diagnostic tests, none were....../27 mutations as either severe (age of onset 20 years), and correctly predicted the age of onset in 37/39 patients. This method should be tested in other Wilson populations....
Robustness of Spann-Wilson segmentation on SAR imagery
Daida, Jason M.; Vesecky, John F.
1992-01-01
The performances of the Spann-Wilson algorithm on simulated synthetic aperture radar (SAR) images with varying degrees of speckle (one to four looks and varying amounts of white noise) is described. One hundred forty-eight test images are considered, of which the algorithm segmented most without any adjustment to the algorithm's parameters. The effect of speckle on fractal boundaries is studied. The effect of varying multiplicative and additive noise distributions for a fixed set of segmentation parameters is examined. The modified Spann-Wilson algorithm on four-look imagery is evaluated.
Face of the giant panda sign in Wilson disease
Directory of Open Access Journals (Sweden)
Sumit Chakraborty
2013-08-01
Full Text Available Wilson disease usually presents with neurologic or hepatic manifestations. Magnetic resonance imaging (MRI of the brain is very informative in diagnosiing of this disease, especially in patients with neurological features. High T2 signal intensity in the corpus striatum is the most commonly encountered MRI finding. The 'face of the giant panda' sign is seen on axial T2-weighted MRI, and results from abnormal signal intensities in the midbrain. Though uncommon, the sign is considered as the pathognomonic MRI sign of Wilson disease.
Notes on winter feeding behavior and molt in Wilson's phalaropes
Burger, J.; Howe, M.
1975-01-01
Wilson's Phalaropes, Steganopus tricolor, migrate in late summer from the prairie regions of North America to their wintering grounds in the highlands of Peru and the inland and coastal waters of Chile, Bolivia, Paraguay, Uruguay, and Argentina (Holmes 1939, Meyer de Schauensee 1970). Reports on these birds from their wintering habitat are few. This paper describes numbers, feeding behavior, and molt of Wilson's Phalaropes wintering in a freshwater marsh in central Argentina. Fieldwork in Argentina was conducted by the senior author. The junior author analyzed molt patterns of birds collected there and added data he collected in North Dakota in 1968 and 1969.
The $q \\bar{q}$ relativistic interaction in the Wilson loop approach
Brambilla, Nora; Vairo, Antonio
1997-01-01
We study the $q \\bar{q}$ relativistic interaction starting from the Feynman-Schwinger representation of the gauge-invariant quark-antiquark Green function. We focus on the one-body limit and discuss the obtained non-perturbative interaction kernel of the Dirac equation.
Null polygonal Wilson loops and minimal surfaces in Anti-de-Sitter space
International Nuclear Information System (INIS)
Alday, Luis F.; Maldacena, Juan
2009-01-01
We consider minimal surfaces in three dimensional anti-de-Sitter space that end at the AdS boundary on a polygon given by a sequence of null segments. The problem can be reduced to a certain generalized Sinh-Gordon equation and to SU(2) Hitchin equations. We describe in detail the mathematical problem that needs to be solved. This problem is mathematically the same as the one studied by Gaiotto, Moore and Neitzke in the context of the moduli space of certain supersymmetric theories. Using their results we can find the explicit answer for the area of a surface that ends on an eight-sided polygon. Via the gauge/gravity duality this can also be interpreted as a certain eight-gluon scattering amplitude at strong coupling. In addition, we give fairly explicit solutions for regular polygons.
McKernan, Lindsey C; Walsh, Colin G; Reynolds, William S; Crofford, Leslie J; Dmochowski, Roger R; Williams, David A
2017-10-09
Psychosocial factors amplify symptoms of Interstitial Cystitis (IC/BPS). While psychosocial self-management is efficacious in other pain conditions, its impact on an IC/BPS population has rarely been studied. The objective of this review is to learn the prevalence and impact of psychosocial factors on IC/BPS, assess baseline psychosocial characteristics, and offer recommendations for assessment and treatment. Following PRISMA guidelines, primary information sources were PubMed including MEDLINE, Embase, CINAHL, and GoogleScholar. Inclusion criteria included: (i) a clearly defined cohort with IC/BPS or with Chronic Pelvic Pain Syndrome provided the IC/BPS cohort was delineated with quantitative results from the main cohort; (ii) all genders and regions; (iii) studies written in English from 1995 to April 14, 2017; (iv) quantitative report of psychosocial factors as outcome measures or at minimum as baseline characteristics. Thirty-four of an initial 642 articles were reviewed. Quantitative analyses demonstrate the magnitude of psychosocial difficulties in IC/BPS, which are worse than average on all measures, and fall into areas of clinical concern for 7 out of 10 measures. Meta-analyses shows mean Mental Component Score of the Short-Form 12 Health Survey (MCS) of 40.80 (SD 6.25, N = 2912), where <36 is consistent with severe psychological impairment. Averaged across studies, the population scored in the range seen in clinical depression (CES-D 19.89, SD 13.12, N = 564) and generalized anxiety disorder (HADS-A 8.15, SD 4.85, N = 465). The psychological impact of IC/BPS is pervasive and severe. Existing evidence of treatment is lacking and suggests self-management intervention may be helpful. © 2017 Wiley Periodicals, Inc.
Finite temperature LGT in a finite box with BPS monopole boundary conditions
International Nuclear Information System (INIS)
Ilgenfritz, E.-M.; Molodtsov, S.V.; Mueller-Preussker, M.; Veselov, A.I.
1999-01-01
Finite temperature SU(2) lattice gauge theory is investigated in a 3D cubic box with fixed boundary conditions (b.c.) provided by a discretized, static BPS monopole solution with varying core scale μ. For discrete μ-values we find stable classical solutions either of electro-magnetic ('dyon') or of purely magnetic type inside the box. Near the deconfinement transition we study the influence of the b.c. on the quantized fields inside the box. In contrast to the purely magnetic background field case, for the dyon case we observe confinement for temperatures above the usual critical one
Exploring the relation between 4D and 5D BPS solutions
Energy Technology Data Exchange (ETDEWEB)
Behrndt, Klaus [Arnold-Sommerfeld-Center for Theoretical Physics, Department fuer Physik, Ludwig-Maximilians-Universitaet Muenchen, Theresienstrasse 37, 80333 Munich (Germany)]. E-mail: behrndt@theorie.physik.uni-muenchen.de; Lopes Cardoso, Gabriel [Arnold-Sommerfeld-Center for Theoretical Physics, Department fuer Physik, Ludwig-Maximilians-Universitaet Muenchen, Theresienstrasse 37, 80333 Munich (Germany)]. E-mail: gcardoso@theorie.physik.uni-muenchen.de; Mahapatra, Swapna [Physics Department, Utkal University, Bhubaneswar 751 004 (India)]. E-mail: swapna@iopb.res.in
2006-01-02
Based on recent proposals linking four and five-dimensional BPS solutions, we discuss the explicit dictionary between general stationary 4D and 5D supersymmetric solutions in N=2 supergravity theories with cubic prepotentials. All these solutions are completely determined in terms of the same set of harmonic functions and the same set of attractor equations. As an example, we discuss black holes and black rings in Godel-Taub-NUT spacetime. Then we consider corrections to the 4D solutions associated with more general prepotentials and comment on analogous corrections on the 5D side.
A refined count of BPS states in the D1/D5 system
Benjamin, Nathan
2017-06-01
We examine the low-lying quarter BPS spectrum of a 2d conformal field theory with target Sym N ( K3) at various points in the moduli space, and look at a more refined count than the ordinary elliptic genus. We compute growth of the spectrum at both the symmetric orbifold point, as well as at the supergravity point in the moduli space. Finally we do a decomposition of the spectra into \\mathcal{N}=4 characters and discuss possible relations to interesting symmetry groups. A similar analysis is done with T 4.
Lifebox | Wilson | Southern African Journal of Anaesthesia and ...
African Journals Online (AJOL)
Southern African Journal of Anaesthesia and Analgesia. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 18, No 1 (2012) >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register. Lifebox. IH Wilson. Abstract.
Nambu-Jona-Lasinio model with Wilson fermions
DEFF Research Database (Denmark)
Rantaharju, Jarno; Drach, Vincent; Pica, Claudio
2017-01-01
We present a lattice study of a Nambu-Jona-Lasinio (NJL) model using Wilson fermions. Four-fermion interactions are a natural part of several extensions of the Standard Model, appearing as a low-energy description of a more fundamental theory. In models of dynamical electroweak symmetry breaking...
BOOK REVIEW: Democracy and Political Life in Nigeria | Wilson ...
African Journals Online (AJOL)
In this review of Victor Dike's book - \\"Democracy and Political Life in Nigeria\\", Inam Wilson underscores the author's attempts to draw a connection between Nigeria's chequered political history and her present economic trajectory to explain why Nigeria is today facing numerous sociopolitical and economic challenges, ...
Values in Higher Education. The Wilson Lecture Series.
Wilson, O. Meredith
The text of a lecture in the University of Arizona Wilson Lecture Series on values in higher education is presented, with responses by Richard H. Gallagher, Jeanne McRae McCarthy, and Raymond H. Thompson. The theme of the talk is that man is by evolution and by necessity a thinking animal, who now finds himself in a technologically dependent…
Genetic analysis of 55 northern Vietnamese patients with Wilson ...
Indian Academy of Sciences (India)
Home; Journals; Journal of Genetics; Volume 96; Issue 6. Genetic analysis of 55 northern Vietnamese patients with Wilson disease: seven novel mutations in ATP7B. LE ANH TUAN PHAM TRONG TUE NGUYEN HOANG BICH NGA LE DAT QUOC TRAN CAM TU HO THINH HUY TRAN VAN THANH TA THE HUNG BUI ...
Transformation of a Free-Wilson matrix into Fourier coefficients
Czech Academy of Sciences Publication Activity Database
Holík, M.; Halámek, Josef
2002-01-01
Roč. 20, - (2002), s. 422 - 428 ISSN 0931-8771 Institutional research plan: CEZ:AV0Z2065902 Keywords : Free-Wilson matrix * Fourier transform * multivariate regression Subject RIV: JA - Electronics ; Optoelectronics, Electrical Engineering Impact factor: 1.558, year: 2002
Middle-aged heterozygous carriers of Wilson's disease do not ...
Indian Academy of Sciences (India)
or infectious disease were excluded), were chosen as control subjects (CS). All WDHzc were subjected to neurological examination. They were questioned about history of any liver. Keywords. autosomal recessive; ATP7B; copper; heterozygous carrier; phenotype; Wilson's disease. Journal of Genetics, Vol. 89, No.
Localization of the Wilson's disease protein in human liver
Schaefer, M; Roelofsen, H; Wolters, H; Hofmann, WJ; Muller, M; Kuipers, F; Stremmel, W; Vonk, RJ
1999-01-01
Background & Aims: Wilson's disease is an autosomal-recessive disorder of copper metabolism that results from the absence or dysfunction of a copper-transporting P-type adenosine triphosphatase that leads to impaired biliary copper excretion and disturbed holoceruloplasmin synthesis, To gain further
Middle-aged heterozygous carriers of Wilson's disease do not ...
Indian Academy of Sciences (India)
Middle-aged heterozygous carriers of Wilson's disease do not present with significant phenotypic deviations related to copper metabolism. G. GROMADZKA1,2∗, G. CHABIK1, T. MENDEL1, A. WIERZCHOWSKA1, M. RUDNICKA2 and A. CZLONKOWSKA1,2∗. 1Institute of Psychiatry and Neurology, Second Department of ...
Nonsymmetric Askey-Wilson polynomials as vector-valued polynomials
Koornwinder, T.H.; Bouzeffour, F.
2011-01-01
Nonsymmetric Askey-Wilson polynomials are usually written as Laurent polynomials. We write them equivalently as 2-vector-valued symmetric Laurent polynomials. Then the Dunkl-Cherednik operator of which they are eigenfunctions, is represented as a 2 × 2 matrix-valued operator. As a new result made
Anaemia and blood transfusion in the ICU | Wilson | Southern ...
African Journals Online (AJOL)
Southern African Journal of Critical Care. Journal Home · ABOUT · Advanced Search · Current Issue · Archives · Journal Home > Vol 20, No 1 (2004) >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register. Anaemia and blood transfusion in the ICU. GS Wilson. Abstract.
Glorieux, Francis H; Devogelaer, Jean-Pierre; Durigova, Michaela; Goemaere, Stefan; Hemsley, Sarah; Jakob, Franz; Junker, Uwe; Ruckle, Jon; Seefried, Lothar; Winkle, Peter J
2017-07-01
This 21-week, open-label, phase 2a trial aimed to evaluate the pharmacodynamics and safety of multiple, escalating infusions of BPS804, a neutralizing, anti-sclerostin antibody, in adults with moderate osteogenesis imperfecta (OI). Patients received BPS804 (three escalating doses each separated by 2 weeks [5, 10, and 20 mg/kg]) or no treatment (reference group). The primary efficacy endpoints were mean changes from baseline to day 43 in: procollagen type 1 N-terminal propeptide (P1NP), procollagen type 1 C-terminal propeptide (P1CP), bone-specific alkaline phosphatase (BSAP), osteocalcin (OC), and type 1 collagen cross-linked C-telopeptide (CTX-1). Mean change from baseline to day 141 in lumbar spine areal bone mineral density (aBMD) was also assessed. BPS804 safety and tolerability were assessed every 2 weeks. Overall, 14 adults were enrolled (BPS804 group: n = 9, mean age 30.7 years, mean aBMD Z-score -2.6; reference group, n = 5, mean age 27.4 years, mean aBMD Z-score -2.2). In the BPS804 group, P1NP, P1CP, BSAP, and OC were increased by 84% (p < 0.001), 53% (p = 0.003), 59% (p < 0.001), and 44% (p = 0.012), respectively, versus baseline (reference: P1NP, +6% [p = 0.651]; P1CP, +5% [p = 0.600]; BSAP, -13% [p = 0.582]; OC, -19% [p = 0.436]). BPS804 treatment downregulated CTX-1 by 44% from baseline (reference: -7%; significance was not tested for this biomarker), and increased aBMD by 4% (p = 0.038; reference group: +1%; p = 0.138). BPS804 was generally well tolerated. There were 32 adverse events reported in nine patients; none was suspected to be treatment-related. There were no treatment-related fractures. BPS804 stimulates bone formation, reduces bone resorption, and increases lumbar spine aBMD in adults with moderate OI. This paves the way for a longer-term, phase 3 trial into the efficacy, safety, and tolerability of BPS804 in patients with OI. © 2017 American Society for Bone and Mineral Research. © 2017
A Ramanujan-type measure for the Askey-Wilson polynomials
Atakishiyev, Natig M.
1995-01-01
A Ramanujan-type representation for the Askey-Wilson q-beta integral, admitting the transformation q to q(exp -1), is obtained. Orthogonality of the Askey-Wilson polynomials with respect to a measure, entering into this representation, is proved. A simple way of evaluating the Askey-Wilson q-beta integral is also given.
Higher derivative corrections to BPS black hole attractors in 4d gauged supergravity
Energy Technology Data Exchange (ETDEWEB)
Hristov, Kiril [Institute for Nuclear Research and Nuclear Energy, Bulgarian Academy of Sciences, Tsarigradsko Chaussee 72, 1784 Sofia (Bulgaria); Katmadas, Stefanos [Dipartimento di Fisica, Università di Milano-Bicocca,I-20126 Milano (Italy); INFN, Sezione di Milano-Bicocca,I-20126 Milano (Italy); Lodato, Ivano [Department of Physics, IISER Pune,Homi Bhaba Road, Pashan, Pune (India)
2016-05-30
We analyze BPS black hole attractors in 4d gauged supergravity in the presence of higher derivative supersymmetric terms, including a Weyl-squared-type action, and determine the resulting corrections to the Bekenstein-Hawking entropy. The near-horizon geometry AdS{sub 2}×S{sup 2} (or other Riemann surface) preserves half of the supercharges in N=2 supergravity with Fayet-Iliopoulos gauging. We derive a relation between the entropy and the black hole charges that suggests via AdS/CFT how subleading corrections contribute to the supersymmetric index in the dual microscopic picture. Depending on the model, the attractors are part of full black hole solutions with different asymptotics, such as Minkowski, AdS{sub 4}, and hvLif{sub 4}. We give explicit examples for each of the asymptotic cases and comment on the implications. Among other results, we find that the Weyl-squared terms spoil the exact two-derivative relation to non-BPS asymptotically flat black holes in ungauged supergravity.
Meson masses in electromagnetic fields with Wilson fermions
Bali, G. S.; Brandt, B. B.; Endrődi, G.; Gläßle, B.
2018-02-01
We determine the light meson spectrum in QCD in the presence of background magnetic fields using quenched Wilson fermions. Our continuum extrapolated results indicate a monotonous reduction of the connected neutral pion mass as the magnetic field grows. The vector meson mass is found to remain nonzero, a finding relevant for the conjectured ρ -meson condensation at strong magnetic fields. The continuum extrapolation was facilitated by adding a novel magnetic field-dependent improvement term to the additive quark mass renormalization. Without this term, sizable lattice artifacts that would deceptively indicate an unphysical rise of the connected neutral pion mass for strong magnetic fields are present. We also investigate the impact of these lattice artifacts on further observables like magnetic polarizabilities and discuss the magnetic field-induced mixing between ρ -mesons and pions. We also derive Ward-Takashi identities for QCD +QED both in the continuum formulation and for (order a -improved) Wilson fermions.
Magnetic resonance imaging of the brain in Wilson's disease.
Thuomas, K A; Aquilonius, S M; Bergström, K; Westermark, K
1993-01-01
Fifteen patients with Wilson's disease were examined, using spin-echo (SE) and gradient-echo (GE) sequences with 0.5 T and 1.5 T magnetic resonance (MR) imagers. They fell into three groups: groups 1 and 2 were examined retrospectively after 3-18 years of treatment, while group 3 was examined prospectively from the start of treatment, after recommencement of treatment, or inadequate treatment. MRI was sensitive to changes in the basal ganglia at sites typical of Wilson's disease and was useful for documenting the effects of treatment. It was found necessary to estimate the relaxation times T1 and T2, to better assess improvement or transient worsening of the disease in the prospective group. Residual cavitation and gliosis could be distinguished in the retrospective group using a subtraction technique.
Wilson's disease: start with psychiatric symptoms. Brain magnetic resonance findings
International Nuclear Information System (INIS)
Nagel, Jorge; Miralles, Sabrina
2007-01-01
Wilson's disease - hepatolenticular degeneration - is an autosomal recessive genetic disorder, characterized by an excessive and toxic accumulation of cooper in different tissues. This accumulation is produced by an inherited defect in cooper's biliary excretion. This rare disorder affects approximately one on 30.000 individuals. Signs and symptoms of hepatic, neurologic and psychiatric disease are the most common clinical presentations of symptomatic Wilson's disease. The diagnosis can usually be made by laboratory tests that find a decreased cooper binding protein in blood called ceruloplasmin, an increase in the excretion of cooper in 24 hour urine and the appearance of corneal Kayser-Fleischer ring. We present a 28 years patient who began with depression and panic attacks, followed by neurologic symptoms. Brain MRI was performed and showed different alterations suggesting the diagnosis of this infrequent sickness. (author) [es
Li, Yin; Perera, Lalith; Coons, Laurel A; Burns, Katherine A; Tyler Ramsey, J; Pelch, Katherine E; Houtman, René; van Beuningen, Rinie; Teng, Christina T; Korach, Kenneth S
2018-01-31
Bisphenol A (BPA) is an endocrine-disrupting chemical (EDC) that might be harmful to human health. Recently, there has been widespread usage of bisphenol chemicals (BPs), such as bisphenol AF (BPAF) and bisphenol S (BPS), as replacements for BPA. However, the potential biological actions, toxicity, and the molecular mechanism of these compounds are still poorly understood. Our objective was to examine the estrogenic effects of BPA, BPAF, and BPS and the molecular mechanisms of action in the estrogen receptor alpha (ERα) complex. In vitro cell models were used to compare the estrogenic effects of BPA, BPAF, and BPS to estrogen. Microarray Assay for Real-Time Coregulator-Nuclear receptor Interaction (MARCoNI) analysis was used to identify coregulators of BPA, BPAF, and BPS, and molecular dynamic (MD) simulations were used to determine the compounds binding in the ERα complex. We demonstrated that BPA and BPAF have agonistic activity for both ERα and ERβ, but BPS has ERα-selective specificity. We concluded that coregulators were differentially recruited in the presence of BPA, BPAF, or BPS. Interestingly, BPS recruited more corepressors when compared to BPA and BPAF. From a series of MD analysis, we concluded that BPA, BPAF, and BPS can bind to the ER-ligand-binding domain with differing energetics and conformations. In addition, the binding surface of coregulator interactions on ERα was characterized for the BPA, BPAF, and BPS complexes. These findings further our understanding of the molecular mechanisms of EDCs, such as BPs, in ER-mediated transcriptional activation, biological activity, and their effects on physiological functions in human health. https://doi.org/10.1289/EHP2505.
Corrections to the Banks-Casher relation with Wilson quarks
Necco, S
2013-01-01
The Banks-Casher relation links the spectral density of the Dirac operator with the existence of a chiral condensate and spontaneous breaking of chiral symmetry. This relation receives corrections from a finite value of the quark mass, a finite space-time volume and, if evaluated on a discrete lattice, from the finite value of the lattice spacing a. We present a status report of a determination of these corrections for Wilson quarks.
Raising and Lowering Operators for Askey-Wilson Polynomials
Directory of Open Access Journals (Sweden)
Siddhartha Sahi
2007-01-01
Full Text Available In this paper we describe two pairs of raising/lowering operators for Askey-Wilson polynomials, which result from constructions involving very different techniques. The first technique is quite elementary, and depends only on the ''classical'' properties of these polynomials, viz. the q-difference equation and the three term recurrence. The second technique is less elementary, and involves the one-variable version of the double affine Hecke algebra.
Wilson line distributions in hot SU(2) gluodynamics
International Nuclear Information System (INIS)
Ilgenfritz, E.M.
1982-01-01
Monte-Carlo results concerning the order parameter related to confinement and its distribution from the point of view of the dilute instanton gas approximation are Discussed. Identified is a threshold effect in the Wilson line distribution with the onset of instantons and established is the relation between the temperature of instanton saturation and the confinement temperature. Some other details of our Monte-Carlo results are reported as well
A conditioning technique for matrix inversion for Wilson fermions
International Nuclear Information System (INIS)
DeGrand, T.A.
1988-01-01
I report a simple technique for conditioning conjugate gradient or conjugate residue matrix inversion as applied to the lattice gauge theory problem of computing the propagator of Wilson fermions. One form of the technique provides about a factor of three speedup over an unconditioned algorithm while running at the same speed as an unconditioned algorithm. I illustrate the method as it is applied to a conjugate residue algorithm. (orig.)
Pontes e rupturas no fabular de Wilson Bueno
Furquim, Fulvia Maria Giaretta de Almeida
2008-01-01
O trabalho tem por objetivo analisar tres obras contemporaneas do escritor paranaense Wilson Bueno (1949- ), que fazem parte de um projeto literario, em que as personagens sao apresentadas de uma visao inicialmente plural, como se apenas uma delas pudesse ser a representacao do todo, para uma optica individualista, caracteristica de um sistema capitalista. Sao elas: Manual de Zoofilia (1991), Jardim Zoologico (1999) e Cachorrros do Ceu (2005). O escritor contemporaneo segue a tradicao dos bes...
Beta-integrals and finite orthogonal systems of Wilson polynomials
International Nuclear Information System (INIS)
Neretin, Yu A
2002-01-01
The integral is calculated and the system of orthogonal polynomials with weight equal to the corresponding integrand is constructed. This weight decreases polynomially, therefore only finitely many of its moments converge. As a result the system of orthogonal polynomials is finite. Systems of orthogonal polynomials related to 5 H 5 -Dougall's formula and the Askey integral is also constructed. All the three systems consist of Wilson polynomials outside the domain of positiveness of the usual weight
Wilson's disease: an analysis of 28 Brazilian children
Directory of Open Access Journals (Sweden)
Rodolpho Truffa Kleine
2012-01-01
Full Text Available OBJECTIVES: Clinical-laboratory and evolutionary analysis of twenty-eight patients with Wilson's disease. METHODS: Twenty-eight children (twelve females and sixteen males with Wilson's disease were evaluated retrospectively between 1987 and 2009, with a follow-up of 72 months (1 - 240 months. The clinical, laboratory, and histologic features at diagnosis were recorded at the end of the study. RESULTS: The median age at diagnosis was 11 years (2 - 18 years. Twelve patients were asymptomatic, seven had hepatitis symptoms, five had raised aminotransferase levels, three had hepatomegaly associated with neurological disorders, one had fulminant hepatitis with hemolytic anemia, and six patients presented with a Kayser-Fleischer ring. A histological analysis revealed that six children had chronic hepatitis, seven had cirrhosis, two had steatosis, one had portal fibrosis, and one had massive necrosis. The treatment consisted of D-penicillamine associated with pyridoxine for 26 patients. Adverse effects were observed in the other two patients: one presented with uncontrollable vomiting and the other demonstrated elastosis perforans serpiginosa. At the end of the study, all 26 treated patients were asymptomatic. Twenty-four of the patients were treated with D-penicillamine and pyridoxine, and two were treated with trientine and zinc sulfate. A liver transplant was performed in one patient with fulminant hepatitis, but the final patient died 48 hours after admission to the intensive care unit. CONCLUSIONS: Family screenings associated with early treatment are important in preventing Wilson's disease symptoms and potentially fatal disease progression. The study suggests that Wilson's disease must be ruled out in children older than two years presenting with abnormal levels of hepatic enzymes because of the heterogeneity of symptoms and the encouraging treatment results obtained so far.
Diverse Functional Properties of Wilson Disease ATP7B Variants
Huster, Dominik; Kühne, Angelika; Bhattacharjee, Ashima; Raines, Lily; Jantsch, Vanessa; Noe, Johannes; Schirrmeister, Wiebke; Sommerer, Ines; Sabri, Osama; Berr, Frieder; Mössner, Joachim; Stieger, Bruno; Caca, Karel; Lutsenko, Svetlana
2012-01-01
BACKGROUND & AIMS Wilson disease is a severe disorder of copper metabolism caused by mutations in ATP7B, which encodes a copper-transporting adenosine triphosphatase. The disease presents with a variable phenotype that complicates the diagnostic process and treatment. Little is known about the mechanisms that contribute to the different phenotypes of the disease. METHODS We analyzed 28 variants of ATP7B from patients with Wilson disease that affected different functional domains; the gene products were expressed using the baculovirus expression system in Sf9 cells. Protein function was analyzed by measuring catalytic activity and copper (64Cu) transport into vesicles. We studied intracellular localization of variants of ATP7B that had measurable transport activities and were tagged with green fluorescent protein in mammalian cells using confocal laser scanning microscopy. RESULTS Properties of ATP7B variants with pathogenic amino-acid substitution varied greatly even if substitutions were in the same functional domain. Some variants had complete loss of catalytic and transport activity, whereas others lost transport activity but retained phosphor-intermediate formation or had partial losses of activity. In mammalian cells, transport-competent variants differed in stability and subcellular localization. CONCLUSIONS Variants in ATP7B associated with Wilson disease disrupt the protein’s transport activity, result in its mislocalization, and reduce its stability. Single assays are insufficient to accurately predict the effects of ATP7B variants the function of its product and development of Wilson disease. These findings will contribute to our understanding of genotype–phenotype correlation and mechanisms of disease pathogenesis. PMID:22240481
Wilson Martins: between the intelligentsia and the university (1951
Directory of Open Access Journals (Sweden)
Névio de Campos
2012-05-01
Full Text Available Abstract The purpose of this article is to analyze the presence of Ortega y Gasset in the Parana’s State group during the 1950s, especially his influence in the thinking of Wilson Martins, and to emphasize the debate on the ideas of the intellectual and the university. The article discusses about the contributions of this Parana’s thinker on the Parana’s university teaching constituting and organizing process, and emphasizes that the Wilson Martins’ role consisted in promoting the debate on the presence of the intellectual person in modern society, attributing the mission as guardian of the moral and herald of cultural renovation, without forgetting the Brazilian and European political-cultural context as the founding background to higher education. It bases itself on the speech entitled “The rebellion against intelligence and the mission of the university”, that occurred at the University of Parana in 1951, and on the work The History of Brazilian Intelligence, written by Wilson Martins.
The Observatory as Laboratory: Spectral Analysis at Mount Wilson Observatory
Brashear, Ronald
2018-01-01
This paper will discuss the seminal changes in astronomical research practices made at the Mount Wilson Observatory in the early twentieth century by George Ellery Hale and his staff. Hale’s desire to set the agenda for solar and stellar astronomical research is often described in terms of his new telescopes, primarily the solar tower observatories and the 60- and 100-inch telescopes on Mount Wilson. This paper will focus more on the ancillary but no less critical parts of Hale’s research mission: the establishment of associated “physical” laboratories as part of the observatory complex where observational spectral data could be quickly compared with spectra obtained using specialized laboratory equipment. Hale built a spectroscopic laboratory on the mountain and a more elaborate physical laboratory in Pasadena and staffed it with highly trained physicists, not classically trained astronomers. The success of Hale’s vision for an astronomical observatory quickly made the Carnegie Institution’s Mount Wilson Observatory one of the most important astrophysical research centers in the world.
[Wilson disease. A case report and review of the literature].
Alva-Moncayo, Edith; Castro-Tarín, María; González-Serrano, Adolfo
2011-01-01
Wilson disease is a problem of cuprum metabolism, with recesive autosomic hereditary transmission and a prevalence of one in 30,000 habitants. The cuprum is deposit in a progressive and irreversible way in the liver and encephalus and it is not liberated with quelant treatment. Neurological manifestations are tremor, disartria, extrapiramidal manifestations or distonia. Ophthalmic exploration shows corneal limb with sign of Kayser-Fleischer. a 15-year-old masculine patient with previous hepatitis outbreak in two times. During the last year he presented distonia, bradicinecious, stiffness and indifference with ictericia. Ophthalmological examination reported Kayser-Fleisher rings. Magnetic resonance of brain showed high dense images in lenticular, pallidus globe and caudate nucleus suggestive of Wilson disease. Ceruloplasmin concentration, cuprum in the liver biopsy confirmed the diagnosis. the importance of the case was the hepatic initial manifestations and two years after presented with inexpressive face, and it was considered a psychiatric disease, but the neurological evaluation and the liver biopsy confirmed the diagnosis of Wilson disease.
Goodaire, EG; Polcino Milies, C
1996-01-01
For the past ten years, alternative loop rings have intrigued mathematicians from a wide cross-section of modern algebra. As a consequence, the theory of alternative loop rings has grown tremendously. One of the main developments is the complete characterization of loops which have an alternative but not associative, loop ring. Furthermore, there is a very close relationship between the algebraic structures of loop rings and of group rings over 2-groups. Another major topic of research is the study of the unit loop of the integral loop ring. Here the interaction between loop rings and group ri
Diagonal form factors and hexagon form factorsII. Non-BPS light operator
Energy Technology Data Exchange (ETDEWEB)
Jiang, Yunfeng [Institut für Theoretische Physik, ETH Zürich,Wolfgang Pauli Strasse 27, CH-8093 Zürich (Switzerland)
2017-01-05
We study the asymptotic volume dependence of the heavy-heavy-light three-point functions in the N=4 Super-Yang-Mills theory using the hexagon bootstrap approach, where the volume is the length of the heavy operator. We extend the analysis of our previous short letter http://dx.doi.org/10.1007/JHEP07(2016)120 to the general case where the heavy operators can be in any rank one sector and the light operator being a generic non-BPS operator. We prove the conjecture of Bajnok, Janik and Wereszczynski http://dx.doi.org/10.1007/JHEP09(2014)050 up to leading finite size corrections.
Conformal superfields and BPS states in $AdS_{4/7}$ geometries
Ferrara, Sergio; Ferrara, Sergio; Sokatchev, Emery
2000-01-01
We carry out a general analysis of the representations of the superconformal algebras OSp(8/4,R) and OSp(8*/2N) in terms of harmonic superspace. We present a construction of their highest-weight UIR's by multiplication of the different types of massless conformal superfields ("supersingletons"). Particular attention is paid to the so-called "short multiplets". Representations undergoing shortening have "protected dimension" and may correspond to BPS states in the dual supergravity theory in anti-de Sitter space. These results are relevant for the classification of multitrace operators in boundary conformally invariant theories as well as for the classification of AdS black holes preserving different fractions of supersymmetry.
1/2-BPS correlators as c = 1 S-matrix
International Nuclear Information System (INIS)
Jevicki, Antal; Yoneya, Tamiaki
2007-01-01
We argue from two complementary viewpoints of Holography that the 2-point correlation functions of 1/2-BPS multi-trace operators in the large-N (planar) limit are nothing but the (Wick-rotated) S-matrix elements of c = 1 matrix model. On the bulk side, we consider an Euclideanized version of the so-called bubbling geometries and show that the corresponding droplets reach the conformal boundary. Then the scattering matrix of fluctuations of the droplets gives directly the two-point correlators through the GKPW prescription. On the Yang-Mills side, we show that the two-point correlators of holomorphic and anti-holomorphic operators are essentially equivalent with the transformation functions between asymptotic in- and out-states of c = 1 matrix model. Extension to non-planar case is also discussed
On effective actions of BPS branes and their higher derivative corrections
Hatefi, Ehsan
2010-01-01
We calculate in detail the disk level S-matrix element of one Ramond-Ramond field and three gauge field vertex operators in the world volume of BPS branes, to find four gauge field couplings to all orders of $\\alpha'$ up to on-shell ambiguity. Then using these infinite couplings we find that the massless pole of the field theory amplitude is exactly equal to the massless pole S-matrix element of this amplitude for the $p=n$ case to all orders of $\\alpha'$. Finally we show that the infinite massless poles and the contact terms of this amplitude for the $p=n+2$ case can be reproduced by the Born-Infeld action and the Wess-Zumino actions, and by their higher derivative corrections.
Diagonal form factors and hexagon form factorsII. Non-BPS light operator
International Nuclear Information System (INIS)
Jiang, Yunfeng
2017-01-01
We study the asymptotic volume dependence of the heavy-heavy-light three-point functions in the N=4 Super-Yang-Mills theory using the hexagon bootstrap approach, where the volume is the length of the heavy operator. We extend the analysis of our previous short letter http://dx.doi.org/10.1007/JHEP07(2016)120 to the general case where the heavy operators can be in any rank one sector and the light operator being a generic non-BPS operator. We prove the conjecture of Bajnok, Janik and Wereszczynski http://dx.doi.org/10.1007/JHEP09(2014)050 up to leading finite size corrections.
New results on the 3-loop heavy flavor corrections in deep-inelastic scattering
Energy Technology Data Exchange (ETDEWEB)
Behring, A.; Bluemlein, J.; Freitas, A. de [Deutsches Elektronen-Synchrotron, Zeuthen (Germany); and others
2013-12-15
We report on recent progress in the calculation of the 3-loop massiveWilson coefficients in deep inelastic scattering at general values of N for neutral- and charged-current reactions in the asymptotic region Q{sup 2}>>m{sup 2}. Four new out of eight massive operator matrix elements and Wilson coefficients have been obtained recently. We also discuss recent results on Feynman graphs containing two massive fermion lines and present complete results for the bubble topologies for all processes.
Höfner, K; Ulrich, S; Berges, R
2017-05-01
Combined therapy of benign prostatic syndrome (BPS) with α 1 -blockers and 5α-reductase (5AR)-inhibitors is recommended according to two leading studies on doxazosin/finasteride and tamsulosin/dutasteride for all 10 in Germany possible combinations (five α 1 -blockers and two 5AR inhibitors). Because tamsulosin and finasteride predominate in the treatment of BPS in Germany, the role of the combination tamsulosin/finasteride and its scientific basis from clinical studies has been investigated. A pharmacoepidemiological extrapolation from receipts of pharmacy data centres showed a strong increase of the combination tamsulosin/finasteride since 2003. As a free combination, tamsulosin/finasteride beside the fixed combination tamsulosin/dutasteride accounts to about 50% of all α 1 -blocker/5AR-inhibitor combinations today. Clinical studies on tamsulosin/finasteride have been published including controlled studies of the combination and both monotherapies. The results of improvement of lower urinary tract symptoms (LUTS), maximum urinary flow rate (Q max ), prostate volume (PV) and prostate-specific antigen (PSA) as well as adverse events and drug safety are in agreement with the leading studies. However, results due to chance cannot be excluded because of deficiencies in study design. A reliable comparison of the risk of progression between tamsulosin/finasteride and both monotherapies is lacking completely. Because of the great coherence and continuous evaluation of available data of all combinations, and with the established strong class effect of monotherapies, a continuation of the therapeutic practice with the combination tamsulosin/finasteride is possible.
Mishra, Nagendra Nath
2015-10-01
Bladder pain syndrome/interstitial cystitis (BPS/IC) is a chronic disease characterized by pelvic pain urgency and frequency. Patients with severe symptoms lead a very miserable life. North American, European and Asian guidelines have been recently promulgated but they differ on many important issues. There is no consensus on its name, definition, investigations and management. Indian guidelines have also been developed and they give more importance to the symptoms in relation to micturition. Though initially believed to be rare or non-existent in India the situation has changed. In Indian patients the presentation is more or less same as the rest of the world but a large percentage have obstructive symptoms and unusual urinary symptoms. Anal discomfort is also common. In India the commonest investigation in all cases of lower urinary tract (LUT) dysfunction is ultrasonography of kidney ureter and bladder with measurement of the post void residual urine volume. Cystoscopy is also done in all the cases to rule out presence of tuberculosis or carcinoma in situ. Bladder pain syndrome/interstitial cystitis (BPS/IC) is not considered to be a clinical disease as it is difficult to rule out all differential diagnosis only from history. Hunner's lesion is very rare. Cystoscopy with hydro distension, oral therapy, intravesical therapy and surgical therapy form the back bone of management. It is difficult to know which treatment is best for a given patient. A staged protocol is followed and all the treatment modalities are applied to the patients in a sequential fashion-starting from the non-invasive to more invasive. Intravesical botox has not been found to be effective and there is no experience with interstim neuromodulation.
Energy Technology Data Exchange (ETDEWEB)
Huang, Chuan-Hsiang; Gabelli, Sandra B.; Oldfield, Eric; Amzel, L. Mario (UIUC); (JHU-MED)
2010-11-15
Bisphosphonates (BPs) are a class of compounds that have been used extensively in the treatment of osteoporosis and malignancy-related hypercalcemia. Some of these compounds act through inhibition of farnesyl diphosphate synthase (FPPS), a key enzyme in the synthesis of isoprenoids. Recently, nitrogen-containing bisphosphonates (N-BPs) used in bone resorption therapy have been shown to be active against Trypanosoma cruzi, the parasite that causes American trypanosomiasis (Chagas disease), suggesting that they may be used as anti-trypanosomal agents. The crystal structures of TcFPPS in complex with substrate (isopentenyl diphosphate, IPP) and five N-BP inhibitors show that the C-1 hydroxyl and the nitrogen-containing groups of the inhibitors alter the binding of IPP and the conformation of two TcFPPS residues, Tyr94 and Gln167. Isothermal titration calorimetry experiments suggest that binding of the first N-BPs to the homodimeric TcFPPS changes the binding properties of the second site. This mechanism of binding of N-BPs to TcFPPS is different to that reported for the binding of the same compounds to human FPPS.
BPS spectrum on AdS{sub 3}×S{sup 3}×S{sup 3}×S{sup 1}
Energy Technology Data Exchange (ETDEWEB)
Eberhardt, Lorenz; Gaberdiel, Matthias R. [Institut für Theoretische Physik, ETH Zurich,CH-8093 Zürich (Switzerland); Gopakumar, Rajesh [International Centre for Theoretical Sciences-TIFR,Survey No. 151, Shivakote, Hesaraghatta Hobli,Bengaluru North, 560 089 (India); Li, Wei [Institute of Theoretical Physics, Chinese Academy of Science,100190 Beijing (China)
2017-03-23
The BPS spectrum of string theory on AdS{sub 3}×S{sup 3}×S{sup 3}×S{sup 1} is determined using a world-sheet description in terms of WZW models. It is found that the theory only has BPS states with j{sup +}=j{sup −} where j{sup ±} refer to the spins of the su(2) algebras of the large N=4 superconformal algebra. We then re-examine the BPS spectrum of the corresponding supergravity and find that, contrary to previous claims in the literature, also in supergravity only the states with j{sup +}=j{sup −} are BPS. This resolves a number of long-standing puzzles regarding the BPS spectrum of string theory and supergravity in this background.
Two-loop QED operator matrix elements with massive external fermion lines
Energy Technology Data Exchange (ETDEWEB)
Bluemlein, Johannes [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany); Freitas, Abilio de [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany); Universidad Simon Bolivar, Caracas (Venezuela). Dept. de Fisica; Neerven, Wilhelmus van [Leiden Univ. (Netherlands). Institut-Lorentz
2011-07-15
The two-loop massive operator matrix elements for the fermionic local twist-2 operators with external massive fermion lines in Quantum Electrodynamics (QED) are calculated up to the constant terms in the dimensional parameter {epsilon}=D-4. We investigate the hypothesis of F. A. Berends et al. (1988) that the 2-loop QED initial state corrections to e{sup +}e{sup -} annihilation into a virtual neutral gauge boson, except power corrections of O((m{sup 2}{sub f}/s){sup k}), k {>=} 1, can be represented in terms of these matrix elements and the massless 2-loop Wilson coefficients of the Drell-Yan process. (orig.)
The Asymptotic Expansion of Lattice Loop Integrals Around the Continuum Limit
International Nuclear Information System (INIS)
Becher, Thomas G
2002-01-01
We present a method of computing any one-loop integral in lattice perturbation theory by systematically expanding around its continuum limit. At any order in the expansion in the lattice spacing, the result can be written as a sum of continuum loop integrals in analytic regularization and a few genuine lattice integrals (''master integrals''). These lattice master integrals are independent of external momenta and masses and can be computed numerically. At the one-loop level, there are four master integrals in a theory with only bosonic fields, seven in HQET and sixteen in QED or QCD with Wilson fermions
One-loop correction to the energy of a wavy line string in AdS5
International Nuclear Information System (INIS)
Buchbinder, E I; Tseytlin, A A
2013-01-01
We consider a computation of one-loop AdS 5 × S 5 superstring correction to the energy radiated by the end-point of a string which moves along a wavy line at the boundary of AdS 5 with a small transverse acceleration (the corresponding classical solution was described by Mikhailov (2003)). We also compute the one-loop effective action for an arbitrary small transverse string fluctuation background. It is related by an analytic continuation to the Euclidean effective action describing one-loop correction to the expectation value of a wavy Wilson line. We show that both the one-loop contribution to the energy and to the Wilson line are controlled by the subleading term in the strong-coupling expansion of the function B(λ) as suggested by Correa et al (2012 J. High Energy Phys. JHEP06(2012)048). (paper)
Catanese, Mary C; Vandenberg, Laura N
2017-03-01
Estrogenic endocrine disrupting chemicals have been shown to disrupt maternal behavior in rodents. We investigated the effects of an emerging xenoestrogen, bisphenol S (BPS), on maternal behavior and brain in CD-1 mice exposed during pregnancy and lactation (F0 generation) and in female offspring exposed during gestation and perinatal development (F1 generation). We observed different effects in F0 and F1 dams for a number of components of maternal behavior, including time on the nest, time spent on nest building, latency to retrieve pups, and latency to retrieve the entire litter. We also characterized expression of estrogen receptor α in the medial preoptic area (MPOA) and quantified tyrosine hydroxylase immunoreactive cells in the ventral tegmental area, 2 brain regions critical for maternal care. BPS-treated females in the F0 generation had a statistically significant increase in estrogen receptor α expression in the caudal subregion of the central MPOA in a dose-dependent manner. In contrast, there were no statistically significant effects of BPS on the MPOA in F1 dams or the ventral tegmental area in either generation. This work demonstrates that BPS affects maternal behavior and brain with outcomes depending on generation, dose, and postpartum period. Many studies examining effects of endocrine disrupting chemicals view the mother as a means by which offspring can be exposed during critical periods of development. Here, we demonstrate that pregnancy and lactation are vulnerable periods for the mother. We also show that developmental BPS exposure alters maternal behavior later in adulthood. Both findings have potential public health implications. Copyright © 2017 by the Endocrine Society.
3 (and even 4) loops renormalization constants for Lattice QCD
International Nuclear Information System (INIS)
Di Renzo, F.; Mantovi, A.; Miccio, V.; Scorzato, L.; Torrero, C.
2006-01-01
We compute renormalization constants for Lattice QCD by means of Numerical Stochastic Perturbation Theory. As an example we discuss Wilson quark bilinears and in particular the 'gold plated' case of Z p /Z s for which we can evaluate the perturbative series up to four loops. By making use of the knowledge of anomalous dimension up to 3 loops in the RI'-MOM scheme, the generic bilinears ca be computed to the same (3rd) order. Finite volume effects are carefully assessed and the continuum limit of the computation is taken in a clean way. The convergence properties of the series can be assessed and a comparison with non-perturbative evaluations of the same quantities can be done. In the end, Lattice Perturbation Theory to high loops is a valuable tool to evaluate renormalization constants for lattice QCD with a very high precision
Comparative assessment of clinical rating scales in Wilson's disease.
Volpert, Hanna M; Pfeiffenberger, Jan; Gröner, Jan B; Stremmel, Wolfgang; Gotthardt, Daniel N; Schäfer, Mark; Weiss, Karl Heinz; Weiler, Markus
2017-07-21
Wilson's disease (WD) is an autosomal recessive disorder of copper metabolism resulting in multifaceted neurological, hepatic, and psychiatric symptoms. The objective of the study was to comparatively assess two clinical rating scales for WD, the Unified Wilson's Disease Rating Scale (UWDRS) and the Global Assessment Scale for Wilson's disease (GAS for WD), and to test the feasibility of the patient reported part of the UWDRS neurological subscale (termed the "minimal UWDRS"). In this prospective, monocentric, cross-sectional study, 65 patients (median age 35 [range: 15-62] years; 33 female, 32 male) with treated WD were scored according to the two rating scales. The UWDRS neurological subscore correlated with the GAS for WD Tier 2 score (r = 0.80; p < 0.001). Correlations of the UWDRS hepatic subscore and the GAS for WD Tier 1 score with both the Model for End Stage Liver Disease (MELD) score (r = 0.44/r = 0.28; p < 0.001/p = 0.027) and the Child-Pugh score (r = 0.32/r = 0.12; p = 0.015/p = 0.376) were weak. The "minimal UWDRS" score significantly correlated with the UWDRS total score (r = 0.86), the UWDRS neurological subscore (r = 0.89), and the GAS for WD Tier 2 score (r = 0.86). The UWDRS neurological and psychiatric subscales and the GAS for WD Tier 2 score are valuable tools for the clinical assessment of WD patients. The "minimal UWDRS" is a practical prescreening tool outside scientific trials.
Adaptive Multigrid Algorithm for the Lattice Wilson-Dirac Operator
International Nuclear Information System (INIS)
Babich, R.; Brower, R. C.; Rebbi, C.; Brannick, J.; Clark, M. A.; Manteuffel, T. A.; McCormick, S. F.; Osborn, J. C.
2010-01-01
We present an adaptive multigrid solver for application to the non-Hermitian Wilson-Dirac system of QCD. The key components leading to the success of our proposed algorithm are the use of an adaptive projection onto coarse grids that preserves the near null space of the system matrix together with a simplified form of the correction based on the so-called γ 5 -Hermitian symmetry of the Dirac operator. We demonstrate that the algorithm nearly eliminates critical slowing down in the chiral limit and that it has weak dependence on the lattice volume.
Syndrome parkinsonien secondaire à une maladie de Wilson chez ...
African Journals Online (AJOL)
Nous apportons une observation d'un cas de la maladie de Wilson, révélé par un syndrome parkinsonien. Le diagnostic a reposé sur les troubles neuropsychiques, la présence de l'anneau cornéen de Kayser-Fleischer, et les troubles du métabolisme du cuivre. Le scanner cérébral était normal, et l'IRM cérébrale a montré ...
Potential of radiocopper in the diagnosis of Wilson disease
International Nuclear Information System (INIS)
Archambaud, F.; Yvart, J.; Moati, F.; Bernard, O.; Dommergues, J.P.; Desgrez, A.; Odievre, M.
1988-01-01
The purpose of the study is to establish if a simple test with 64 Cu is a valuable means of differenciating homozygotes for the ''Wilson's disease gene'' from heterozygous carriers and normal subjects for copper metabolism. A group of 73 subjects were studied. The only parameter which appears to be interesting is the percentage of administrated 64 Cu incorporated into ceruloplasmin at 48h. This test appears to be interesting to predict the disease and to avoid biopsy for determination of hepatic copper concentration [fr
Parallel tempering in full QCD with Wilson fermions
International Nuclear Information System (INIS)
Ilgenfritz, E.-M.; Kerler, W.; Mueller-Preussker, M.; Stueben, H.
2002-01-01
We study the performance of QCD simulations with dynamical Wilson fermions by combining the hybrid Monte Carlo algorithm with parallel tempering on 10 4 and 12 4 lattices. In order to compare tempered with standard simulations, covariance matrices between subensembles have to be formulated and evaluated using the general properties of autocorrelations of the parallel tempering algorithm. We find that rendering the hopping parameter κ dynamical does not lead to an essential improvement. We point out possible reasons for this observation and discuss more suitable ways of applying parallel tempering to QCD
Wilson's disease in children: clinical and diagnostic features
International Nuclear Information System (INIS)
Ayesha, H.; Choudhry, A.A.; Javed, M.T.; Javed, F.
2002-01-01
Objective: To study the clinical and diagnostic laboratory features of Wilsons disease in children and adolescents. Design: A prospective cohort study. Place and Duration of study: The study included patients diagnosed as Wilson s disease at the Department of Pediatrics Allied Hospital, Punjab medical College, Faisalabad from May 1997 to June 2001. Patients and methods: Patients presenting with liver or suggestive neurological disease were investigated. Others were diagnosed as a result of family screening. Diagnosis of neurologic disease was made if two of the following were present: Typical neurological findings, Kayser Fleischer corneal rings and low serum ceruloplasmin ( 100 mu gm) free serum copper (>10 mu gm/dl). In other forms and for family screening, 24 hours. Urinary copper (> 100 mu gm), free serum copper (>10 mu gm/dl), and wherever possible liver biopsy for histopathology and cytochemical staining by rubeanic acid was also done. Results: Twenty-seven patients with a mean age of 10.2 years were diagnosed as suffering from Wilson disease. Mean age for hepatic and neurological disease was 9 years and 11.5 years respectively. Youngest patient (neurologic) was 6 years old. 48% cases presented with neurological, 41% with hepatic and 4% with skeletal manifestations while 7 % were asymptomatic. Mean duration of symptoms before diagnosis was 6.1 months. Dysarthria (84.6%), tremors (69.2%), rigidity and poor school performance and hand writing (61.5%), dysphagia (46.1%) and dystonia (38.5%), were the most common neurologic findings. Chronic liver disease was seen in 73 % while acute forms were seen in 27 % cases. Two cases presented with fulminant hepatic failure. Consanguineous marriage of the parents was found in 70 % and family history of disease was present in 65 % cases. K-F (Kayser Fleischer) rings and low serum ceruloplasmin(<20 mg/dl) was found in 85% of all patients. In non neurologic types other tests of copper metabolism were done. Elevated urinary
Topology, the Wilson flow and the HMC algorithm
Luscher, Martin
2010-01-01
An old and apparently persistent problem in numerical lattice QCD is that the simulations tend to get trapped in a sector of fixed topological charge when the lattice spacing is taken to zero. The effect sets in very rapidly and may invalidate the simulation results in certain cases. In this talk, the issue is discussed using the Wilson flow as a tool. The flow has a simple scaling behaviour and allows one to understand how exactly the topological sectors emerge in the continuum limit. Further studies however suggest that the observed slowdown of the simulations at small lattice spacings is only partly caused by the emergence of the sectors.
Loop Transfer Matrix and Loop Quantum Mechanics
International Nuclear Information System (INIS)
Savvidy, George K.
2000-01-01
The gonihedric model of random surfaces on a 3d Euclidean lattice has equivalent representation in terms of transfer matrix K(Q i ,Q f ), which describes the propagation of loops Q. We extend the previous construction of the loop transfer matrix to the case of nonzero self-intersection coupling constant κ. We introduce the loop generalization of Fourier transformation which allows to diagonalize transfer matrices, that depend on symmetric difference of loops only and express all eigenvalues of 3d loop transfer matrix through the correlation functions of the corresponding 2d statistical system. The loop Fourier transformation allows to carry out the analogy with quantum mechanics of point particles, to introduce conjugate loop momentum P and to define loop quantum mechanics. We also consider transfer matrix on 4d lattice which describes propagation of memebranes. This transfer matrix can also be diagonalized by using the generalized Fourier transformation, and all its eigenvalues are equal to the correlation functions of the corresponding 3d statistical system. In particular the free energy of the 4d membrane system is equal to the free energy of 3d gonihedric system of loops and is equal to the free energy of 2d Ising model. (author)
Eight dimensional QCD at one loop
Gracey, J. A.
2018-01-01
The Lagrangian for a non-Abelian gauge theory with an S U (Nc) symmetry and a linear covariant gauge fixing is constructed in eight dimensions. The renormalization group functions are computed at one loop with the special cases of Nc=2 and 3 treated separately. By computing the critical exponents derived from these in the large Nf expansion at the Wilson-Fisher fixed point it is shown that the Lagrangian is in the same universality class as the two dimensional non-Abelian Thirring model and quantum chromodynamics (QCD). As the eight dimensional Lagrangian contains new quartic gluon operators not present in four dimensional QCD, we compute in parallel the mixing matrix of four dimensional dimension 8 operators in pure Yang-Mills theory.
Interest rates in quantum finance: the Wilson expansion and Hamiltonian.
Baaquie, Belal E
2009-10-01
Interest rate instruments form a major component of the capital markets. The Libor market model (LMM) is the finance industry standard interest rate model for both Libor and Euribor, which are the most important interest rates. The quantum finance formulation of the Libor market model is given in this paper and leads to a key generalization: all the Libors, for different future times, are imperfectly correlated. A key difference between a forward interest rate model and the LMM lies in the fact that the LMM is calibrated directly from the observed market interest rates. The short distance Wilson expansion [Phys. Rev. 179, 1499 (1969)] of a Gaussian quantum field is shown to provide the generalization of Ito calculus; in particular, the Wilson expansion of the Gaussian quantum field A(t,x) driving the Libors yields a derivation of the Libor drift term that incorporates imperfect correlations of the different Libors. The logarithm of Libor phi(t,x) is defined and provides an efficient and compact representation of the quantum field theory of the Libor market model. The Lagrangian and Feynman path integrals of the Libor market model of interest rates are obtained, as well as a derivation given by its Hamiltonian. The Hamiltonian formulation of the martingale condition provides an exact solution for the nonlinear drift of the Libor market model. The quantum finance formulation of the LMM is shown to reduce to the industry standard Bruce-Gatarek-Musiela-Jamshidian model when the forward interest rates are taken to be exactly correlated.
Chelating polymeric beads as potential therapeutics for Wilson's disease.
Mattová, Jana; Poučková, Pavla; Kučka, Jan; Skodová, Michaela; Vetrík, Miroslav; Stěpánek, Petr; Urbánek, Petr; Petřík, Miloš; Nový, Zbyněk; Hrubý, Martin
2014-10-01
Wilson's disease is a genetic disorder caused by a malfunction of ATPase 7B that leads to high accumulation of copper in the organism and consequent toxic effects. We propose a gentle therapy to eliminate the excessive copper content with oral administration of insoluble non-resorbable polymer sorbents containing selective chelating groups for copper(II). Polymeric beads with the chelating agents triethylenetetramine, N,N-di(2-pyridylmethyl)amine, and 8-hydroxyquinoline (8HQB) were investigated. In a preliminary copper uptake experiment, we found that 8HQB significantly reduced copper uptake (using copper-64 as a radiotracer) after oral administration in Wistar rats. Furthermore, we measured organ radioactivity in rats to demonstrate that 8HQB radiolabelled with iodine-125 is not absorbed from the gastrointestinal tract after oral administration. Non-resorbability and the blockade of copper uptake were also confirmed with small animal imaging (PET/CT) in mice. In a long-term experiment with Wistar rats fed a diet containing the polymers, we have found that there were no signs of polymer toxicity and the addition of polymers to the diet led to a significant reduction in the copper contents in the kidneys, brains, and livers of the rats. We have shown that polymers containing specific ligands could potentially be novel therapeutics for Wilson's disease. Copyright © 2014 Elsevier B.V. All rights reserved.
Half BPS states in AdS5 x Yp,q
International Nuclear Information System (INIS)
Gava, Edi; Narain, K.S.; Milanesi, Giuseppe; O'Loughlin, Martin
2008-01-01
We study a class of solutions of IIB supergravity which are asymptotically AdS 5 x Y p,q . They have an R x SO(4) x SU(2) x U(1) isometry and preserve half of the 8 supercharges of the background geometry. They are described by a set of second order differential equations that we have found and analysed in a previous paper, where we studied 1/8 BPS states in the maximally supersymmetric AdS 5 x S 5 background. These geometries correspond to certain chiral primary operators of the N = 1 superconformal quiver theories, dual to IIB theory on AdS 5 x Y p,q . We also show how to recover the AdS 5 x Y p,q backgrounds by suitably doubling the number of preserved supersymmetries. We then solve the differential equations perturbatively in a large AdS 5 radius expansion, imposing asymptotic AdS 5 x Y p,q boundary conditions. We compute the global baryonic and mesonic charges, including the R-charge. As for the computation of the mass, i.e. the conformal dimension Δ of the dual field theory operators, which is notoriously subtle in asymptotically AdS backgrounds, we adopt the general formalism due to Wald and collaborators, which gives a finite result, and verify the relation Δ = 3R/2, demanded by the N = 1 superconformal algebra
N=2 SUGRA BPS multi-center black holes and freudenthal triple systems
Directory of Open Access Journals (Sweden)
Torrente-Lujan E.
2015-01-01
Full Text Available We present a detailed description of N = 2 stationary BPS multicenter black hole solutions for quadratic prepotentials with an arbitrary number of centers and scalar fields making a systematic use of the algebraic properties of the matrix of second derivatives of the prepotential, S, which in this case is a scalar-independent matrix. The anti-involution matrix S can be understood as a Freudenthal duality x̃ = Sx. We show that this duality can be generalized to “Freudenthal transformations” x→λexp(θSx=ax+bx˜$x \\to \\lambda \\exp \\left( {\\theta S} \\rightx = ax + b\\tilde x$ under which the horizon area, ADM mass and intercenter distances scale up leaving constant the scalars at the fixed points. In the special case λ = 1, “S-rotations”, the transformations leave invariant the solution. The standard Freudenthal duality can be written as x˜=exp (π2S x$\\tilde x = {\\rm{exp }}\\left( {{\\pi \\over 2}S} \\right{\\rm{ }}x$. We argue that these generalized transformations leave invariant not only the quadratic preotential theories but also the general stringy extremal quartic form Δ4, Δ4(x = Δ4(cos θx + sin θx̃ and therefore its entropy at lowest order.
Dimensional reduction of BPS attractors in AdS gauged supergravities
Hristov, Kiril
2014-12-01
We relate across dimensions BPS attractors of black strings and black holes of various topology in gauged supergravities with nontrivial scalar potential. The attractors are of the form AdS2,3 × Σ2,3 in 4, 5, and 6 dimensions, and can be generalized to some higher dimensional analogs. Even though the attractor geometries admit standard Kaluza-Klein and Scherk-Schwarz reductions, their asymptotic AdS spaces in general do not. The resulting lower dimensional objects are black holes with runaway asymptotics in supergravity theories with no maximally symmetric vacua. Such classes of solutions are already known to exist in literature, and results here suggest an interpretation in terms of their higher-dimensional origin that often has a full string theory embedding. In a particular relevant example, the relation between 5d Benini-Bobev black strings [1, 2] and a class of 4d Cacciatori-Klemm black holes [3] is worked out in full detail, providing a type IIB and dual field theory description of the latter solutions. As a consistency check, the Cardy formula for the field theory is shown to match the Bekenstein-Hawking entropy for horizon topology of any genus.
BPS/CFT Correspondence III: Gauge Origami Partition Function and qq-Characters
Nekrasov, Nikita
2017-12-01
We study generalized gauge theories engineered by taking the low energy limit of the Dp branes wrapping {X × {T}^{p-3}} , with X a possibly singular surface in a Calabi-Yau fourfold Z. For toric Z and X the partition function can be computed by localization, making it a statistical mechanical model, called the origami. The random variables are the ensembles of Young diagrams. The building block of the gauge origami is associated with a tetrahedron, whose edges are colored by vector spaces. We show the properly normalized partition function is an entire function of the Coulomb moduli, for generic values of the {Ω} -background parameters. The orbifold version of the theory defines the qq-character operators, with and without the surface defects. The analytic properties are the consequence of a relative compactness of the moduli spaces {M({ěc n}, k)} of crossed and spiked instantons, demonstrated in "BPS/CFT correspondence II: instantons at crossroads, moduli and compactness theorem".
Universal properties of superconformal OPEs for 1/2 BPS operators in $3\\leq D \\leq 6$
Ferrara, Sergio; Ferrara, Sergio; Sokatchev, Emery
2002-01-01
We give a general analysis of OPEs of 1/2 BPS superfield operators for the $D=3,4,5,6$ superconformal algebras OSp(8/4,R), PSU(2,2), F${}_4$ and OSp($8^*/4$) which underlie maximal AdS supergravity in $4\\leq D+1\\leq 7$. \\\\ The corresponding three-point functions can be formally factorized in a way similar to the decomposition of a generic superconformal UIR into a product of supersingletons. This allows for a simple derivation of branching rules for primary superfields. The operators of protected conformal dimension which may appear in the OPE are classified and are shown to be either 1/2 or 1/4 BPS, or semishort. As an application, we discuss the "non-renormalization" of extremal $n$-point correlators.
Mersha, Mahlet D; Patel, Bansri M; Patel, Dipen; Richardson, Brittany N; Dhillon, Harbinder S
2015-09-17
Bisphenol-A (BPA) is a polymerizing agent used in plastic bottles and several routinely used consumer items. It is classified among endocrine disrupting chemicals suspected to cause adverse health effects in mammals ranging from infertility and cancer to behavioral disorders. Work with the invertebrate lab model Caenorhabditis elegans has shown that BPA affects germ cells by disrupting double-stranded DNA break repair mechanisms. The current study utilizes this model organism to provide insight into low-dose and long-term behavioral effects of BPA and bisphenol-S (BPS), a supposed safer replacement for BPA. Experiments presented in our report demonstrate that the effects of embryonic exposure to considerably low levels of BPA persist into adulthood, affecting neural functionality as assayed by measuring habituation to mechano-sensory stimuli in C. elegans. These results are noteworthy in that they are based on low-dose exposures, following the rationale that subtler effects that may not be morphologically apparent are likely to be discernible through behavioral changes. In addition, we report that embryonic exposure to BPS follows a pattern similar to BPA. Building upon previous observations using the C. elegans model, we have shown that exposure of embryos to BPA and BPS affects their behavior as adults. These long-term effects are in line with recommended alternate low-dose chemical safety testing approaches. Our observation that the effects of BPS are similar to BPA is not unexpected, considering their structural similarity. This, to our knowledge, is the first reported behavioral study on low-dose toxicity of any endocrine disrupting chemical in C. elegans.
In vitro and in vivo estrogenic activity of BPA, BPF and BPS in zebrafish-specific assays.
Le Fol, Vincent; Aït-Aïssa, Selim; Sonavane, Manoj; Porcher, Jean-Marc; Balaguer, Patrick; Cravedi, Jean-Pierre; Zalko, Daniel; Brion, François
2017-08-01
Bisphenol A (BPA) is a widely used chemical that has been extensively studied as an endocrine-disrupting chemical (EDC). Other bisphenols sharing close structural features with BPA, are increasingly being used as alternatives, increasing the need to assess associated hazards to the endocrine system. In the present study, the estrogenic activity of BPA, bisphenol S (BPS) and bisphenol F (BPF) was assessed by using a combination of zebrafish-specific mechanism-based in vitro and in vivo assays. The three bisphenols were found to efficiently transactivate all zebrafish estrogen receptor (zfER) subtypes in zebrafish hepatic reporter cell lines (ZELH-zfERs). BPA was selective for zfERα while BPS and BPF were slightly more potent on zfERβ subtypes. We further documented the estrogenic effect in vivo by quantifying the expression of brain aromatase using a transgenic cyp19a1b-GFP zebrafish embryo assay. All three bisphenols induced GFP in a concentration-dependent manner. BPS only partially induced brain aromatase at the highest tested concentrations (>30µM) while BPA and BPF strongly induced GFP, in an ER-dependent manner, at 1-10µM. Furthermore, we show that BPF strongly induced vitellogenin synthesis in adult male zebrafish. Overall, this study demonstrates the estrogenic activity of BPA, BPF and BPS in different cell- and tissue-contexts and at different stages of development. Differences between in vitro and in vivo responses are discussed in light of selective ER activation and the fate of the compounds in the models. This study confirms the relevance of combining cellular and whole-organism bioassays in a unique model species for the hazard assessment of candidate EDCs. Copyright © 2017 Elsevier Inc. All rights reserved.
Pawson, Adam J.; Sharman, Joanna L.; Benson, Helen E.; Faccenda, Elena; Alexander, Stephen P.H.; Buneman, O. Peter; Davenport, Anthony P.; McGrath, John C.; Peters, John A.; Southan, Christopher; Spedding, Michael; Yu, Wenyuan; Harmar, Anthony J.
2014-01-01
The International Union of Basic and Clinical Pharmacology/British Pharmacological Society (IUPHAR/BPS) Guide to PHARMACOLOGY (http://www.guidetopharmacology.org) is a new open access resource providing pharmacological, chemical, genetic, functional and pathophysiological data on the targets of approved and experimental drugs. Created under the auspices of the IUPHAR and the BPS, the portal provides concise, peer-reviewed overviews of the key properties of a wide range of established and potential drug targets, with in-depth information for a subset of important targets. The resource is the result of curation and integration of data from the IUPHAR Database (IUPHAR-DB) and the published BPS ‘Guide to Receptors and Channels’ (GRAC) compendium. The data are derived from a global network of expert contributors, and the information is extensively linked to relevant databases, including ChEMBL, DrugBank, Ensembl, PubChem, UniProt and PubMed. Each of the ∼6000 small molecule and peptide ligands is annotated with manually curated 2D chemical structures or amino acid sequences, nomenclature and database links. Future expansion of the resource will complete the coverage of all the targets of currently approved drugs and future candidate targets, alongside educational resources to guide scientists and students in pharmacological principles and techniques. PMID:24234439
Finite size effects in lattice QCD with dynamical Wilson fermions
Energy Technology Data Exchange (ETDEWEB)
Orth, B.
2004-06-01
Due to limited computing resources choosing the parameters for a full lattice QCD simulation always amounts to a compromise between the competing objectives of a lattice spacing as small, quarks as light, and a volume as large as possible. Aiming at pushing unquenched simulations with the standard Wilson action towards the computationally expensive regime of small quark masses, the GRAL project addresses the question whether computing time can be saved by sticking to lattices with rather modest numbers of grid sites and extrapolating the finite-volume results to the infinite volume (prior to the usual chiral and continuum extrapolations). In this context we investigate in this work finite-size effects in simulated light hadron masses. Understanding their systematic volume dependence may not only help saving computer time in light quark simulations with the Wilson action, but also guide future simulations with dynamical chiral fermions which for a foreseeable time will be restricted to rather small lattices. We analyze data from hybrid Monte Carlo simulations with the N{sub f} = 2 Wilson action at two values of the coupling parameter, {beta} = 5.6 (lattice spacing {alpha} {approx} 0.08 fm) and {beta} = 5.32144 ({alpha} {approx} 0.13 fm). The larger {beta} corresponds to the coupling used previously by SESAM/T{chi}L. The considered hopping parameters {kappa} = 0.1575, 0.158 (at the larger {beta}) and {kappa} = 0.1665 (at the smaller {beta}) correspond to quark masses of 85, 50 and 36% of the strange quark mass, respectively. At each quark mass we study at least three different lattice extents in the range from L = 10 to L = 24 (0.85-2.04 fm). Estimates of autocorrelation times in the stochastic updating process and of the computational cost of every run are given. For each simulated sea quark mass we calculate quark propagators and hadronic correlation functions in order to extract the pion, rho and nucleon masses as well as the pion decay constant and the quark mass
Lattice QCD at finite temperature with Wilson fermions
International Nuclear Information System (INIS)
Pinke, Christopher
2014-01-01
The subatomic world is governed by the strong interactions of quarks and gluons, described by Quantum Chromodynamics (QCD). Quarks experience confinement into colour-less objects, i.e. they can not be observed as free particles. Under extreme conditions such as high temperature or high density, this constraint softens and a transition to a phase where quarks and gluons are quasi-free particles (Quark-Gluon-Plasma) can occur. This environment resembles the conditions prevailing during the early stages of the universe shortly after the Big Bang. The phase diagram of QCD is under investigation in current and future collider experiments, for example at the Large Hadron Collider (LHC) or at the Facility for Antiproton and Ion Research (FAIR). Due to the strength of the strong interactions in the energy regime of interest, analytic methods can not be applied rigorously. The only tool to study QCD from first principles is given by simulations of its discretised version, Lattice QCD (LQCD). These simulations are in the high-performance computing area, hence, the numerical aspects of LQCD are a vital part in this field of research. In recent years, Graphic Processing Units (GPUs) have been incorporated in these simulations as they are a standard tool for general purpose calculations today. In the course of this thesis, the LQCD application CL 2 QCD has been developed, which allows for simulations on GPUs as well as on traditional CPUs, as it is based on OpenCL. CL 2 QCD constitutes the first application for Wilson type fermions in OpenCL. It provides excellent performance and has been applied in physics studies presented in this thesis. The investigation of the QCD phase diagram is hampered by the notorious sign-problem, which restricts current simulation algorithms to small values of the chemical potential. Theoretically, studying unphysical parameter ranges allows for constraints on the phase diagram. Of utmost importance is the clarification of the order of the finite
War, Medicine, and Cultural Diplomacy in the Americas: Frank Wilson and Brazilian cardiology.
Kropf, Simone P; Howell, Joel D
2017-10-01
American cultural diplomacy played a key role in the institutionalization of Brazilian cardiology. In 1942, Frank Wilson, an internationally recognized pioneer in electrocardiography, made an extended wartime visit to Rio de Janeiro and São Paulo. The visit was sponsored by the United States Department of State as part of Roosevelt's Good Neighbor Policy and brought Wilson together with a group of physicians who would establish the specialty of cardiology in Brazil. This US cultural and diplomatic initiative strengthened an academic network that was already evolving and would eventually prove to be of benefit to both sides. Latin American physicians began in the 1920s to visit Wilson's laboratory at the University of Michigan, where they established the relationships on which Wilson would build. While affiliation with the "Wilson school" advanced the cause of Brazilian cardiologists who sought to establish themselves as specialists, cooperation with Latin American physicians benefitted Wilson in his pursuit of wider recognition for his innovations in the use of electrocardiography (ECG). Wilson's identity as a scientific ambassador to Latin America helped in legitimating his approach to the clinical application of the ECG. A close examination of Wilson's relationship to Brazilian cardiology demonstrates the role played by science and medicine as a part of wartime cultural diplomacy, as well as the dynamics of the transnational circulation of scientific knowledge and practices. © The Author 2017. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.
"Mens Sana in Corpore Sano": Human Values in Thomas Wilson's "The Arte of Rhetorique."
Luehring, Janet
In 1553 the work that is touted as the first complete book written in English on rhetoric was published, Thomas Wilson's "Arte of Rhetorique." It became so popular it enjoyed eight printings within its century. Wilson was not a person to translate and read just for knowledge; he believed that knowledge should be imparted to the general…
Clinical presentation and mutations in Danish patients with Wilson disease
DEFF Research Database (Denmark)
Møller, Lisbeth Birk; Horn, Nina; Jeppesen, Tina Dysgaard
2011-01-01
consistently indicative of WND, with the exception of the 24-h urine-Cu test, which is always outside the normal range. Mutations were identified in 100% of the screened ATP7B alleles (70 unrelated), including five novel mutations: p.1021K; p.G1158V; p.L1304F; IVS20-2A>G; Ex5_6del. In all, 70% of mutations...... were found in exons 8, 14, 17, 18, and 20. The most frequent mutation, p.H1069Q, comprised 18%. We propose a new and simple model that correlates genotype and age of onset. By assuming that the milder of two mutations is 'functionally dominant' and determines the age of onset, we classified 25....../27 mutations as either severe (age of onset 20 years), and correctly predicted the age of onset in 37/39 patients. This method should be tested in other Wilson populations....
Holomorphic variables in magnetized brane models with continuous Wilson lines
Camara, Pablo G; Dudas, Emilian
2010-01-01
We analyze the action of the target-space modular group in toroidal type IIB orientifold compactifications with magnetized D-branes and continuous Wilson lines. The transformation of matter fields agree with that of twisted fields in heterotic compactifications, constituting a check of type I/heterotic duality. We identify the holomorphic N = 1 variables for these compactifications. Matter fields and closed string moduli are both redefined by open string moduli. The redefinition of matter fields can be read directly from the perturbative Yukawa couplings, whereas closed string moduli redefinitions are obtained from D-brane instanton superpotential couplings. The resulting expressions reproduce and generalize, in the presence of internal magnetic fields, previous results in the literature.
Wilson's disease in children with blindness: an atypical presentation.
Rukunuzzaman, M; Karim, M B; Rahman, M M; Islam, M S; Mazumder, M W
2013-01-01
Wilson's disease (WD) is an autosomal recessive disease affecting copper metabolism causing copper induced organ damage. Common organs involved are liver and central nervous system. But RBC, eye, kidneys and bone may also be affected. In WD main defect remains in copper transporter protein p type ATPase resulting from gene mutation in chromosome 13. Neurological manifestations in WD develop due to deposition of copper in different brain areas like basal ganglia, cerebral cortex, corticospinal and corticobulbar pathway. Different types of neurological manifestations develop in WD but visual impairment is very rare. A 14 years old boy of WD presented to us with blindness, tremor and slurred speech along with end stage liver disease. Blindness was thought to be due to optic neuropathy which reversed after drug treatment.
Escherichia coli Protein Expression System for Acetylcholine Binding Proteins (AChBPs).
Abraham, Nikita; Paul, Blessy; Ragnarsson, Lotten; Lewis, Richard J
2016-01-01
Nicotinic acetylcholine receptors (nAChR) are ligand gated ion channels, identified as therapeutic targets for a range of human diseases. Drug design for nAChR related disorders is increasingly using structure-based approaches. Many of these structural insights for therapeutic lead development have been obtained from co-crystal structures of nAChR agonists and antagonists with the acetylcholine binding protein (AChBP). AChBP is a water soluble, structural and functional homolog of the extracellular, ligand-binding domain of nAChRs. Currently, AChBPs are recombinantly expressed in eukaryotic expression systems for structural and biophysical studies. Here, we report the establishment of an Escherichia coli (E. coli) expression system that significantly reduces the cost and time of production compared to the existing expression systems. E. coli can efficiently express unglycosylated AChBP for crystallography and makes the expression of isotopically labelled forms feasible for NMR. We used a pHUE vector containing an N-terminal His-tagged ubiquitin fusion protein to facilitate AChBP expression in the soluble fractions, and thus avoid the need to recover protein from inclusion bodies. The purified protein yield obtained from the E. coli expression system is comparable to that obtained from existing AChBP expression systems. E. coli expressed AChBP bound nAChR agonists and antagonists with affinities matching those previously reported. Thus, the E. coli expression system significantly simplifies the expression and purification of functional AChBP for structural and biophysical studies.
Escherichia coli Protein Expression System for Acetylcholine Binding Proteins (AChBPs.
Directory of Open Access Journals (Sweden)
Nikita Abraham
Full Text Available Nicotinic acetylcholine receptors (nAChR are ligand gated ion channels, identified as therapeutic targets for a range of human diseases. Drug design for nAChR related disorders is increasingly using structure-based approaches. Many of these structural insights for therapeutic lead development have been obtained from co-crystal structures of nAChR agonists and antagonists with the acetylcholine binding protein (AChBP. AChBP is a water soluble, structural and functional homolog of the extracellular, ligand-binding domain of nAChRs. Currently, AChBPs are recombinantly expressed in eukaryotic expression systems for structural and biophysical studies. Here, we report the establishment of an Escherichia coli (E. coli expression system that significantly reduces the cost and time of production compared to the existing expression systems. E. coli can efficiently express unglycosylated AChBP for crystallography and makes the expression of isotopically labelled forms feasible for NMR. We used a pHUE vector containing an N-terminal His-tagged ubiquitin fusion protein to facilitate AChBP expression in the soluble fractions, and thus avoid the need to recover protein from inclusion bodies. The purified protein yield obtained from the E. coli expression system is comparable to that obtained from existing AChBP expression systems. E. coli expressed AChBP bound nAChR agonists and antagonists with affinities matching those previously reported. Thus, the E. coli expression system significantly simplifies the expression and purification of functional AChBP for structural and biophysical studies.
A Mathematica package for calculation of one-loop penguins in FCNC processes
Bednyakov, Alexander Vadimovich; Tanyıldızı, Şükrü Hanif
2015-09-01
In this work, we present a Mathematica package Peng4BSM@LO which calculates the contributions to the Wilson Coefficients of certain effective operators originating from the one-loop penguin Feynman diagrams. Both vector and scalar external legs are considered. The key feature of our package is the ability to find the corresponding expressions in almost any New Physics model which extends the SM and has no flavor changing neutral current (FCNC) transitions at the tree level.
Little strings, quasi-topological sigma model on loop group, and toroidal Lie algebras
Ashwinkumar, Meer; Cao, Jingnan; Luo, Yuan; Tan, Meng-Chwan; Zhao, Qin
2018-03-01
We study the ground states and left-excited states of the Ak-1 N = (2 , 0) little string theory. Via a theorem by Atiyah [1], these sectors can be captured by a supersymmetric nonlinear sigma model on CP1 with target space the based loop group of SU (k). The ground states, described by L2-cohomology classes, form modules over an affine Lie algebra, while the left-excited states, described by chiral differential operators, form modules over a toroidal Lie algebra. We also apply our results to analyze the 1/2 and 1/4 BPS sectors of the M5-brane worldvolume theory.
Little strings, quasi-topological sigma model on loop group, and toroidal Lie algebras
Directory of Open Access Journals (Sweden)
Meer Ashwinkumar
2018-03-01
Full Text Available We study the ground states and left-excited states of the Ak−1 N=(2,0 little string theory. Via a theorem by Atiyah [1], these sectors can be captured by a supersymmetric nonlinear sigma model on CP1 with target space the based loop group of SU(k. The ground states, described by L2-cohomology classes, form modules over an affine Lie algebra, while the left-excited states, described by chiral differential operators, form modules over a toroidal Lie algebra. We also apply our results to analyze the 1/2 and 1/4 BPS sectors of the M5-brane worldvolume theory.
Renormalization of loop functions for all loops
International Nuclear Information System (INIS)
Brandt, R.A.; Neri, F.; Sato, M.
1981-01-01
It is shown that the vacuum expectation values W(C 1 ,xxx, C/sub n/) of products of the traces of the path-ordered phase factors P exp[igcontour-integral/sub C/iA/sub μ/(x)dx/sup μ/] are multiplicatively renormalizable in all orders of perturbation theory. Here A/sub μ/(x) are the vector gauge field matrices in the non-Abelian gauge theory with gauge group U(N) or SU(N), and C/sub i/ are loops (closed paths). When the loops are smooth (i.e., differentiable) and simple (i.e., non-self-intersecting), it has been shown that the generally divergent loop functions W become finite functions W when expressed in terms of the renormalized coupling constant and multiplied by the factors e/sup -K/L(C/sub i/), where K is linearly divergent and L(C/sub i/) is the length of C/sub i/. It is proved here that the loop functions remain multiplicatively renormalizable even if the curves have any finite number of cusps (points of nondifferentiability) or cross points (points of self-intersection). If C/sub γ/ is a loop which is smooth and simple except for a single cusp of angle γ, then W/sub R/(C/sub γ/) = Z(γ)W(C/sub γ/) is finite for a suitable renormalization factor Z(γ) which depends on γ but on no other characteristic of C/sub γ/. This statement is made precise by introducing a regularization, or via a loop-integrand subtraction scheme specified by a normalization condition W/sub R/(C-bar/sub γ/) = 1 for an arbitrary but fixed loop C-bar/sub γ/. Next, if C/sub β/ is a loop which is smooth and simple except for a cross point of angles β, then W(C/sub β/) must be renormalized together with the loop functions of associated sets S/sup i//sub β/ = ]C/sup i/ 1 ,xxx, C/sup i//sub p/i] (i = 2,xxx,I) of loops C/sup i//sub q/ which coincide with certain parts of C/sub β/equivalentC 1 1 . Then W/sub R/(S/sup i//sub β/) = Z/sup i/j(β)W(S/sup j//sub β/) is finite for a suitable matrix Z/sup i/j
Meer, S. Winters-Van Der; Man, R.A. de; Berg, A.P. van den; Houwen, R.H.; Linn, F.H.; Oijen, M.G. van; Siersema, P.D.; Erpecum, K.J. van
2015-01-01
BACKGROUND AND AIMS: Data on risk of hepatocellular carcinoma (HCC) in patients with Wilson disease are scarce. We determine HCC risk in a well-defined cohort of Wilson patients. METHODS: All patients with a confirmed diagnosis of Wilson disease (Leipzig score >/= 4) in three Dutch university
van Meer, Suzanne; de Man, Robert A.; van den Berg, Aad P.; Houwen, Roderick H. J.; Linn, Francisca H. H.; van Oijen, Martijn G. H.; Siersema, PD; van Erpecum, Karel J.
Background and AimsData on risk of hepatocellular carcinoma (HCC) in patients with Wilson disease are scarce. We determine HCC risk in a well-defined cohort of Wilson patients. MethodsAll patients with a confirmed diagnosis of Wilson disease (Leipzig score4) in three Dutch university referral
Tribl, Gotthard G; Bor-Seng-Shu, Edson; Trindade, Mateus C; Lucato, Leandro T; Teixeira, Manoel J; Barbosa, Egberto R
2014-09-01
To describe characteristics of REM sleep behavior disorder in Wilson's disease. Questionnaire-based interviews (patients and relatives), neurological examinations, two-week prospective dream-diary, video-polysomnography, transcranial sonography, MRI. Four Wilson's disease cases with REM sleep behavior disorder were described; three had REM sleep behavior disorder as initial symptom. All showed mesencephalic tegmental/tectal sonographic hyperechogenicities and two presented ponto-mesencephalic tegmental MRI hyperintensities. This first description of REM sleep behavior disorder in Wilson's disease in literature documents REM sleep behavior disorder as a possible presenting symptom of Wilson's disease and adds further evidence to the parallelism of Parkinson's disease and Wilson's disease in phenotype and brainstem topography, which ought to be further studied. REM sleep behavior disorder has prognostic relevance for neurodegeneration in α-synucleinopathies. In Wilson's disease, usefulness of early diagnosis and treatment are already well established. REM sleep behavior disorder in Wilson's disease offers a possible theoretical model for potential early treatment in this extrapyramidal and brainstem paradigm syndrome, previewing the possibility of neuroprotective treatment for REM sleep behavior disorder in "pre-clinical" Parkinson's disease.
Peace through Institutions: Woodrow Wilson and the Paris Peace Conference
Directory of Open Access Journals (Sweden)
Burak Küntay
2014-12-01
Full Text Available As we approach the centennial of World War I, it is fitting to undertake a retrospective, academic review of the institutions devised in the war’s aftermath. The efforts to build and sustain a global order ensuring peace and cooperation in the international community - which ultimately failed with the beginning of a Second World War—constitute telling and timely lessons for world politics today. This paper looks critically at America’s role in World War I, diplomatic talks preceding the signature of the treaty of Versailles, and domestic and international reactions to President Woodrow Wilson’s signature idealism.The paper begins with a historical overview of how World War I began in Europe in an effort to contextualize the entrance of the United States in 1917, two and a half years after the war began. Since Woodrow Wilson originally promoted American neutrality, and U.S. public opinion had mostly favored isolationism until World War I, Wilson’s presidency represents a historic shift in American foreign policy to interventionism and eventually, its post-Cold War “global policeman” status. Assessing the main actors of WWI and America’s role in it serves to frame Woodrow Wilson’s asymmetrical reception within his own country. In the U.S., Wilson’s foreign affairs record is characterized by his intervention in Mexico, his original attempt to remain uninvolved in Europe’s war, and his failed attempt to keep peace after the war. Wilson garnered domestic support for U.S. entrance with his call to “make the world safe for democracy.” Using such overt idealistic rhetoric in the foreign policymaking decision process was novel at the time, but sounds all too familiar today. Post-WWI, Wilson’s fight with Congress and the U.S. not entering into the League of Nations resembles rifts between U.S. administrations and their Congresses in recent times, and it arguably indirectly contributed to the occurrence of the World War II. As U
Rijkenberg, Saskia; Stilma, Willemke; Bosman, Robert J; van der Meer, Nardo J; van der Voort, Peter H J
2017-08-01
The Behavioral Pain Scale (BPS) and Critical-Care Pain Observation Tool (CPOT) are behavioral pain assessment tools for sedated and unconscious critically ill patients. The aim of this study was to compare the reliability, internal consistency, and discriminant validation of the BPS and the CPOT simultaneously in mechanically ventilated patients after cardiac surgery. A prospective, observational cohort study. A 20-bed closed-format intensive care unit with mixed medical, surgical, and cardiac surgery patients in a teaching hospital in Amsterdam, The Netherlands. The study comprised 72 consecutive intubated and mechanically ventilated patients after cardiac surgery who were not able to self-report pain. Two nurses assessed the BPS and CPOT simultaneously and independently at the following 4 moments: rest, a nonpainful procedure (oral care), rest, and a painful procedure (turning). Both scores showed a significant increase of 2 points between rest and turning. The median BPS score of nurse 1 showed a significant increase of 1 point between rest and the nonpainful procedure (oral care), whereas both median CPOT scores did not change. The interrater reliability of the BPS and CPOT showed fair-to-good agreement of 0.74 overall. During the periods of rest 1 and rest 2, values ranged from 0.24 to 0.46. Cronbach's alpha values for the BPS were 0.62 (nurse 1) and 0.59 (nurse 2) compared with 0.65 and 0.58, respectively, for the CPOT. The BPS and CPOT are reliable and valid pain assessment tools in a daily clinical setting. However, the discriminant validation of both scores seems less satisfactory in sedated or agitated patients and this topic requires further investigation. Copyright © 2017 Elsevier Inc. All rights reserved.
Directory of Open Access Journals (Sweden)
Sunarsih Sunarsih
2017-04-01
Full Text Available Nyeri persalinan dapat menyebabkan aktivitas uterus yang tidak terkoordinasi yang akan mengakibatkan persalinan lama, yang akhirnya dapat mengancam kehidupan janin dan ibu. Berbagai upaya dilakukan untuk menurunkan nyeri pada persalinan, antara lain dengan terapi massage dan teknik relaksasi. Hasil survey di Bidan Praktik Swasta (BPS Ernawati kepada 5 orang ibu bersalin didapat sebanyak 80% orang mengatakan nyeri yang tidak tertahan saat proses persalinan namun berkurang setelah dilakukan massage dan relaksasi. Tujuan penelitian diketahui berbedaan terapi massage dengan terapi relaksasi dalam mengurangi nyeri persalinan di BPS Ernawati Kecamatan Banyumas tahun 2016.Penelitian kuantitatif dengan rancangan quasi eksperimen. Penelitian dilaksanakan pada tanggal 12 Maret 2016 sampai dengan 25 Juli tahun 2016. Populasi dalam penelitian ini adalah seluruh ibu yang akan melahirkan rerata 31 orang, sampel berjumlah 40 orang,teknik sampling yang digunakan dalam penelitian ini adalah sistematik sampling. Variabel penelitian terapi massage, teknik relaksasi dan nyeri persalinan. Analisis data uji statistik dengan uji t. Hasil penelitian didapatkan rata-rata nyeri persalinan sebelum diberikan massage adalah 6,90 dengan dan setelah adalah 4,90 dengan beda mean 2,0, rata-rata nyeri persalinan sebelum diberikan teknik relaksasi adalah 6,90 dan setelah adalah 5,25 dengan beda mean 1,65. Hasil uji statistik nilai p-value=0,000yang berarti terdapatperbedaan terapi massage dengan terapi relaksasi dalam mengurangi nyeri persalinan di BPS Ernawati Kecamatan Banyumas tahun 2016. Petugas Kesehatan diharapkan lebih meningkatkan keterampilan dalam pengurangan rasa nyeri non farmakologi, seperti massagedan relaksasi dengan benar sehingga pasien merasa nyaman.
Two-loop operator matrix elements for massive fermionic local twist-2 operators in QED
International Nuclear Information System (INIS)
Bluemlein, J.; Freitas, A. de; Universidad Simon Bolivar, Caracas; Neerven, W.L. van
2011-11-01
We describe the calculation of the two--loop massive operator matrix elements with massive external fermions in QED. We investigate the factorization of the O(α 2 ) initial state corrections to e + e - annihilation into a virtual boson for large cms energies s >>m 2 e into massive operator matrix elements and the massless Wilson coefficients of the Drell-Yan process adapting the color coefficients to the case of QED, as proposed by F. A. Berends et. al. (Nucl. Phys. B 297 (1988)429). Our calculations show explicitly that the representation proposed there works at one-loop order and up to terms linear in ln (s/m 2 e ) at two-loop order. However, the two-loop constant part contains a few structural terms, which have not been obtained in previous direct calculations. (orig.)
On loop extensions and cohomology of loops
Benítez, Rolando Jiménez; Meléndez, Quitzeh Morales
2015-01-01
In this paper are defined cohomology-like groups that classify loop extensions satisfying a given identity in three variables for association identities, and in two variables for the case of commutativity. It is considered a large amount of identities. This groups generalize those defined in works of Nishigori [2] and of Jhonson and Leedham-Green [4]. It is computed the number of metacyclic extensions for trivial action of the quotient on the kernel in one particular case for left Bol loops a...
Neutron transport in irradiation loops (IRENE loop)
International Nuclear Information System (INIS)
Sarsam, Maher.
1980-09-01
This thesis is composed of two parts with different aspects. Part one is a technical description of the loop and its main ancillary facilities as well as of the safety and operational regulations. The measurement methods on the model of the ISIS reactor and on the loop in the OSIRIS reactor are described. Part two deals with the possibility of calculating the powers dissipated by each rod of the fuel cluster, using appropriate computer codes, not only in the reflector but also in the core and to suggest a method of calculation [fr
U(1) Wilson lattice gauge theories in digital quantum simulators
Muschik, Christine; Heyl, Markus; Martinez, Esteban; Monz, Thomas; Schindler, Philipp; Vogell, Berit; Dalmonte, Marcello; Hauke, Philipp; Blatt, Rainer; Zoller, Peter
2017-10-01
Lattice gauge theories describe fundamental phenomena in nature, but calculating their real-time dynamics on classical computers is notoriously difficult. In a recent publication (Martinez et al 2016 Nature 534 516), we proposed and experimentally demonstrated a digital quantum simulation of the paradigmatic Schwinger model, a U(1)-Wilson lattice gauge theory describing the interplay between fermionic matter and gauge bosons. Here, we provide a detailed theoretical analysis of the performance and the potential of this protocol. Our strategy is based on analytically integrating out the gauge bosons, which preserves exact gauge invariance but results in complicated long-range interactions between the matter fields. Trapped-ion platforms are naturally suited to implementing these interactions, allowing for an efficient quantum simulation of the model, with a number of gate operations that scales polynomially with system size. Employing numerical simulations, we illustrate that relevant phenomena can be observed in larger experimental systems, using as an example the production of particle-antiparticle pairs after a quantum quench. We investigate theoretically the robustness of the scheme towards generic error sources, and show that near-future experiments can reach regimes where finite-size effects are insignificant. We also discuss the challenges in quantum simulating the continuum limit of the theory. Using our scheme, fundamental phenomena of lattice gauge theories can be probed using a broad set of experimentally accessible observables, including the entanglement entropy and the vacuum persistence amplitude.
Open boundary condition, Wilson flow and the scalar glueball mass
International Nuclear Information System (INIS)
Chowdhury, Abhishek; Harindranath, A.; Maiti, Jyotirmoy
2014-01-01
A major problem with periodic boundary condition on the gauge fields used in current lattice gauge theory simulations is the trapping of topological charge in a particular sector as the continuum limit is approached. To overcome this problem open boundary condition in the temporal direction has been proposed recently. One may ask whether open boundary condition can reproduce the observables calculated with periodic boundary condition. In this work we find that the extracted lowest glueball mass using open and periodic boundary conditions at the same lattice volume and lattice spacing agree for the range of lattice scales explored in the range 3 GeV≤(1/a)≤5 GeV. The problem of trapping is overcome to a large extent with open boundary and we are able to extract the glueball mass at even larger lattice scale ≈ 5.7 GeV. To smoothen the gauge fields we have used recently proposed Wilson flow which, compared to HYP smearing, exhibits better systematics in the extraction of glueball mass. The extracted glueball mass shows remarkable insensitivity to the lattice spacings in the range explored in this work, 3 GeV≤(1/a)≤5.7 GeV.
Wilson lines for AdS5 black strings
International Nuclear Information System (INIS)
Hristov, Kiril; Katmadas, Stefanos
2015-01-01
We describe a simple method of extending AdS 5 black string solutions of 5d gauged supergravity in a supersymmetric way by addition of Wilson lines along a circular direction in space. When this direction is chosen along the string, and due to the specific form of 5d supergravity that features Chern-Simons terms, the existence of magnetic charges automatically generates conserved electric charges in a 5d analogue of the Witten effect. Therefore we find a rather generic, model-independent way of adding electric charges to already existing solutions with no backreaction from the geometry or breaking of any symmetry. We use this method to explicitly write down more general versions of the Benini-Bobev black strings (http://dx.doi.org/10.1103/PhysRevLett.110.061601, http://dx.doi.org/10.1007/JHEP06(2013)005) and comment on the implications for the dual field theory and the similarities with generalizations of the Cacciatori-Klemm black holes (http://dx.doi.org/10.1007/JHEP01(2010)085) in AdS 4 .
Wilson's disease: cranial MRI observations and clinical correlation
International Nuclear Information System (INIS)
Sinha, S.; Taly, A.B.; Prashanth, L.K.; Venugopal, K.S.; Arunodaya, G.R.; Swamy, H.S.; Ravishankar, S.; Vasudev, M.K.
2006-01-01
Study of MRI changes may be useful in diagnosis, prognosis and better understanding of the pathophysiology of Wilson's disease (WD). We aimed to describe and correlate the MRI abnormalities of the brain with clinical features in WD. MRI evaluation was carried out in 100 patients (57 males, 43 females; mean age 19.3±8.9 years) using standard protocols. All but 18 patients were on de-coppering agents. Their history, clinical manifestations and scores for severity of disease were noted. The mean duration of illness and treatment were 8.3±10.8 years and 7.5±7.1 years respectively. MRI of the brain was abnormal in all the 93 symptomatic patients. The most conspicuous observations were atrophy of the cerebrum (70%), brainstem (66%) and cerebellum (52%). Signal abnormalities were also noted: putamen (72%), caudate (61%), thalami (58%), midbrain (49%), pons (20%), cerebral white matter (25%), cortex (9%), medulla (12%) and cerebellum (10%). The characteristic T2-W globus pallidal hypointensity (34%), ''Face of giant panda'' sign (12%), T1-W striatal hyperintensity (6%), central pontine myelinosis (7%), and bright claustral sign (4%) were also detected. MRI changes correlated with disease severity scores (P<0.001) but did not correlate with the duration of illness. MRI changes were universal but diverse and involved almost all the structures of the brain in symptomatic patients. A fair correlation between MRI observations and various clinical features provides an explanation for the protean manifestations of the disease. (orig.)
DEFF Research Database (Denmark)
Reno II, Barry Len; Korhonen, F.J.; Stout, J.H.
the Grenville Orogen in North America. Many of these terranes record evidence of two orogenies: the Labradorian Orogeny at ca. 1710-1600 Ma, and the Grenville Orogeny at ca. 1080-980 Ma. The rocks in the Wilson Lake terrane are interpreted to have been subjected to peak pressures of ~0.95 GPa...... and ~930°C during the Labradorian Orogeny (Korhonen et al., in prep., Stability of sapphirine + quartz in the Wilson Lake terrane: calculated equilibria in NCKFMASHTO). The final amalgamation of the Wilson Lake terrane over the underlying Parautochthonous Belt is interpreted to have occurred during...... the Grenville Orogeny, when the terrane was subjected to a lower-T (500-350°C) overprinting. However, petrologic and chronologic evidence for the Grenville orogeny is limited in the Wilson Lake terrane. Here we present results from a monazite chemical (U-Th)-Pb chronologic study in order to provide constraints...
LBA Regional Vegetation and Soils, 1-Degree (Wilson and Henderson-Sellers)
National Aeronautics and Space Administration — This data set is a subset of a global vegetation and soils data set by Wilson and Henderson-Sellers (1985a). The subset was created for the study area of the Large...
Mowat-Wilson-syndrom hos tre danske børn
DEFF Research Database (Denmark)
Nissen, Karin Bækgaard; Søndergaard, Charlotte; Thelle, Thomas
2011-01-01
Mowat-Wilson syndrome (MWS) is an autosomal dominant intellectual disability syndrome characterised by unique facial features and congenital anomalies such as Hirschsprung disease, congenital heart defects, corpus callosum agenesis and urinary tract anomalies. Some cases also present epilepsy...
LBA Regional Vegetation and Soils, 1-Degree (Wilson and Henderson-Sellers)
National Aeronautics and Space Administration — ABSTRACT: This data set is a subset of a global vegetation and soils data set by Wilson and Henderson-Sellers (1985a). The subset was created for the study area of...
2005-01-01
sim tut Simulation Tutorial Interactive Media Element This interactive tutorial on MATLAB covers the For Loop and the While Loop functions. Examples are provided with step-by-step animated explanations. The interactions involve entering MATLAB instructions and observing the outcomes. Self-check questions are provided to help learners determine their level of understanding of the content presented. EC1010 Introduction to MATLAB
International Nuclear Information System (INIS)
Moeller, S.V.
1983-02-01
The procedures used to operate the water loop of the Institute of Nuclear Enginering (IEN) in Brazil are presented. The aim is to help future operators of the training water loop in the operation technique and in a better comprehension of the phenomena occured during the execution of an experience. (E.G.) [pt
The epsilon regime of chiral perturbation theory with Wilson-type fermions
Energy Technology Data Exchange (ETDEWEB)
Jansen, K. [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany). John von Neumann-Inst. fuer Computing NIC; Shindler, A. [Liverpool Univ. (United Kingdom). Theoretical Physics Division
2009-11-15
In this proceeding contribution we report on the ongoing effort to simulate Wilson-type fermions in the so called epsilon regime of chiral perturbation theory (cPT).We present results for the chiral condensate and the pseudoscalar decay constant obtained with Wilson twisted mass fermions employing two lattice spacings, two different physical volumes and several quark masses. With this set of simulations we make a first attempt to estimate the systematic uncertainties. (orig.)
Exceptional Askey-Wilson-type polynomials through Darboux-Crum transformations
International Nuclear Information System (INIS)
Odake, S; Sasaki, R
2010-01-01
An alternative derivation is presented of the infinitely many exceptional Wilson and Askey-Wilson polynomials, which were introduced by the present authors in 2009. Darboux-Crum transformations intertwining the discrete quantum mechanical systems of the original and the exceptional polynomials play an important role. Infinitely many continuous Hahn polynomials are derived in the same manner. The present method provides a simple proof of the shape invariance of these systems as in the corresponding cases of the exceptional Laguerre and Jacobi polynomials.
The epsilon regime of chiral perturbation theory with Wilson-type fermions
International Nuclear Information System (INIS)
Jansen, K.; Shindler, A.
2009-11-01
In this proceeding contribution we report on the ongoing effort to simulate Wilson-type fermions in the so called epsilon regime of chiral perturbation theory (cPT).We present results for the chiral condensate and the pseudoscalar decay constant obtained with Wilson twisted mass fermions employing two lattice spacings, two different physical volumes and several quark masses. With this set of simulations we make a first attempt to estimate the systematic uncertainties. (orig.)
Oldfield, Lauren M; Hatfull, Graham F
2014-10-01
The PR promoter of mycobacteriophage BPs directs early lytic gene expression and is under the control of the BPs repressor, gp33. Reporter gene fusions showed that PR has modest activity in an extrachromosomal context but has activity that is barely detectable in an integrated context, even in the absence of its repressor. Mutational dissection of PR showed that it uses a canonical -10 hexamer recognized by SigA, and mutants with mutations to the sequence 5'-TATAMT had the greatest activities. It does not contain a 5'-TGN-extended -10 sequence, although mutants with mutations creating an extended -10 sequence had substantially increased promoter activity. Mutations in the -35 hexamer also influenced promoter activity but were strongly context dependent, and similar substitutions in the -35 hexamer differentially affected promoter activity, depending on the -10 and extended -10 motifs. This warrants caution in the construction of synthetic promoters or the bioinformatic prediction of promoter activity. Combinations of mutations throughout PR generated a calibrated series of promoters for expression of stably integrated recombinant genes in both Mycobacterium smegmatis and M. tuberculosis, with maximal promoter activity being more than 2-fold that of the strong hsp60 promoter. Copyright © 2014, American Society for Microbiology. All Rights Reserved.
Sharman, Joanna L; Faccenda, Elena; Southan, Chris; Pawson, Adam J; Ireland, Sam; Gray, Alasdair J G; Bruce, Liam; Alexander, Stephen P H; Anderton, Stephen; Bryant, Clare; Davenport, Anthony P; Doerig, Christian; Fabbro, Doriano; Levi-Schaffer, Francesca; Spedding, Michael
2018-01-01
Abstract The IUPHAR/BPS Guide to PHARMACOLOGY (GtoPdb, www.guidetopharmacology.org) and its precursor IUPHAR-DB, have captured expert-curated interactions between targets and ligands from selected papers in pharmacology and drug discovery since 2003. This resource continues to be developed in conjunction with the International Union of Basic and Clinical Pharmacology (IUPHAR) and the British Pharmacological Society (BPS). As previously described, our unique model of content selection and quality control is based on 96 target-class subcommittees comprising 512 scientists collaborating with in-house curators. This update describes content expansion, new features and interoperability improvements introduced in the 10 releases since August 2015. Our relationship matrix now describes ∼9000 ligands, ∼15 000 binding constants, ∼6000 papers and ∼1700 human proteins. As an important addition, we also introduce our newly funded project for the Guide to IMMUNOPHARMACOLOGY (GtoImmuPdb, www.guidetoimmunopharmacology.org). This has been ‘forked’ from the well-established GtoPdb data model and expanded into new types of data related to the immune system and inflammatory processes. This includes new ligands, targets, pathways, cell types and diseases for which we are recruiting new IUPHAR expert committees. Designed as an immunopharmacological gateway, it also has an emphasis on potential therapeutic interventions. PMID:29149325
Energy Technology Data Exchange (ETDEWEB)
Xi Juan [College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072 (China); Ji Xinghu [College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072 (China); Zhang Shaohong [College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072 (China); Xiang Fan Vocational and Technical College, Xiangfan 441021 (China); Ai Xinping [College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072 (China); He Zhike [College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072 (China)]. E-mail: zhkhe@whu.edu.cn
2005-06-13
The chemiluminescence mechanism of tris-(4,7-diphenyl-1,10-phenanthrolinedisulfonic acid)ruthenium(II) (RuBPS)-Ce(IV) system and the effects of two diuretics, hydrochlorothiazide and furosemide, on its chemiluminescence intensity were investigated in detail. It was found that each of the two diuretics could enhance the chemiluminescence emission intensity of RuBPS-Ce(IV) system, based on which, they were sensitively detected by chemiluminescence analysis, respectively. Under the optimum experimental conditions, the linear range and detection limit of hydrochlorothiazide were 2.5 x 10{sup -3} to 6.0 x 10{sup -1} {mu}g ml{sup -1} and 1.0 x 10{sup -3} {mu}g ml{sup -1}, respectively; those of furosemide were 1.0 x 10{sup -2} to 4.0 {mu}g ml{sup -1} and 8.8 x 10{sup -3} {mu}g ml{sup -1}, respectively. The proposed method has been applied to analyze the pharmaceuticals with satisfied results.
On the chirally rotated Schroedinger functional with Wilson fermions
Energy Technology Data Exchange (ETDEWEB)
Gonzalez Lopez, Jenifer
2011-05-25
There are many phenomena in nature, which are closely linked to the low energy regime of QCD. From a theoretical point of view, these low energy phenomena can be dealt with only by means of non-perturbative methods. It is the central goal of this thesis to provide a framework for such a nonperturbative renormalization. For that purpose, we employ a 4-dimensional lattice as a regulator of QCD. As a renormalization scheme, we propose a finite volume Schroedinger functional scheme and here in particular, the chirally rotated Schroedinger functional ({chi}SF). We first perform analytical studies of the {chi}SF at tree-level of perturbation theory, in the continuum and on the lattice. We study the eigenvalue spectrum of the continuum Dirac operator, equipped with chirally rotated SF boundary conditions, and derive the corresponding quark propagator. We then determine the tree-level quark propagator on the lattice, employing massless Wilson fermions as a regulator of the theory. Beyond tree-level, all studies are performed in the quenched approximation of QCD, as a first, computationally much simpler step to understand the properties of the newly proposed {chi}SF scheme. One of the main targets of the present work, has been to perform the non-perturbative tuning of the two required coefficients of the {chi}SF scheme, such that a well defined continuum limit can be reached. We demonstrate, as the first main result of this thesis, that the tuning is feasible and that, moreover, physical quantities are insensitive to the particular tuning condition. As in any lattice regularization with SF-like boundary conditions, there are also in the {chi}SF a couple of counterterms at the boundaries, whose coefficients need to be tuned in order to remove the O(a) discretization effects originated at the boundaries. However, besides these boundary O(a) effects, the {chi}SF is expected to be compatible with bulk automatic O(a)-improvement. We show here that, indeed, the scaling behavior
Dystonic Dysarthria in Wilson Disease: Efficacy of Zolpidem.
Poujois, Aurélia; Pernon, Michaela; Trocello, Jean-Marc; Woimant, France
2017-01-01
Wilson disease (WD) is a rare genetic disorder characterized by copper overload in the liver and the brain. Neurological presentations are mainly related to the accumulation of copper in the basal ganglia, the brainstem, and the cerebellum. Dysarthria is a frequent symptom, with dystonic, spastic, or parkinsonian components and is usually resistant to medical or voice rehabilitation therapies. Here, we report the case of a patient with WD diagnosed at the age of 12, who presented a severe and constant dysarthria from dystonic origin which was unresponsive to benzodiazepines and anticholinergic drugs. When she was 25-year-old, she tried zolpidem at bedtime for sleeping difficulties and reported a paradoxical effect of this drug on her voice. To confirm the effect of zolpidem on her dystonic dysarthria, we realized a full evaluation of her dysarthria at baseline without zolpidem and after 4 days of treatment by 10 mg twice a day. Lexical access was evaluated by the semantic fluency; dysarthria by the Intelligibility Score, the spontaneous speech and reading rates, the maximum phonation time on the sustained vowel [a] and by a perceptive evaluation. Two hours after the intake of zolpidem, improvement of all the parameters tested, with the exception of the maximum phonation time, was observed. Semantic fluency increased by 59%, the spontaneous speech rate by 88% and the reading rate by 76%. General dystonia remained unchanged and the tolerance of zolpidem was satisfactory. Since then, the patient takes zolpidem 5 mg five times a day, and 4 years later shows persistent improvement in oral communication and a good drug tolerance. In this single-case study, we showed that regular daytime intake of zolpidem could have a persisting effect on a complex dystonic dysarthria that was resistant to usual medical treatments.
Dystonic Dysarthria in Wilson Disease: Efficacy of Zolpidem
Directory of Open Access Journals (Sweden)
Aurélia Poujois
2017-10-01
Full Text Available Wilson disease (WD is a rare genetic disorder characterized by copper overload in the liver and the brain. Neurological presentations are mainly related to the accumulation of copper in the basal ganglia, the brainstem, and the cerebellum. Dysarthria is a frequent symptom, with dystonic, spastic, or parkinsonian components and is usually resistant to medical or voice rehabilitation therapies. Here, we report the case of a patient with WD diagnosed at the age of 12, who presented a severe and constant dysarthria from dystonic origin which was unresponsive to benzodiazepines and anticholinergic drugs. When she was 25-year-old, she tried zolpidem at bedtime for sleeping difficulties and reported a paradoxical effect of this drug on her voice. To confirm the effect of zolpidem on her dystonic dysarthria, we realized a full evaluation of her dysarthria at baseline without zolpidem and after 4 days of treatment by 10 mg twice a day. Lexical access was evaluated by the semantic fluency; dysarthria by the Intelligibility Score, the spontaneous speech and reading rates, the maximum phonation time on the sustained vowel [a] and by a perceptive evaluation. Two hours after the intake of zolpidem, improvement of all the parameters tested, with the exception of the maximum phonation time, was observed. Semantic fluency increased by 59%, the spontaneous speech rate by 88% and the reading rate by 76%. General dystonia remained unchanged and the tolerance of zolpidem was satisfactory. Since then, the patient takes zolpidem 5 mg five times a day, and 4 years later shows persistent improvement in oral communication and a good drug tolerance. In this single-case study, we showed that regular daytime intake of zolpidem could have a persisting effect on a complex dystonic dysarthria that was resistant to usual medical treatments.
Three-point functions of twist-two operators in {N}=4 SYM at one loop
Plefka, Jan; Wiegandt, Konstantin
2012-10-01
We calculate three-point functions of two protected operators and one twist-two operator with arbitrary even spin j in {N}=4 super Yang-Mills theory to one-loop order. In order to carry out the calculations we project the indices of the spin j operator to the light-cone and evaluate the correlator in a soft-limit where the momentum coming in at the spin j operator becomes zero. This limit largely simplifies the perturbative calculation, since all three-point diagrams effectively reduce to two-point diagrams and the dependence on the one-loop mixing matrix drops out completely. The results of our direct calculation are in agreement with the structure constants obtained by F.A. Dolan and H. Osborn from the operator product expansion of four-point functions of half-BPS operators.
... of tissue that protrude through the intestinal wall (diverticulosis) Certain medical conditions, including Crohn's disease, radiation enteritis, ... History of radiation therapy to the abdomen Diabetes Diverticulosis of the small intestine Complications A blind loop ...
National Research Council Canada - National Science Library
Heier, Jeffrey E
2008-01-01
...) processes via the Observe, Orient, Decide, and Act (OODA) Loop concept. As defined by Wikipedia, a mashup is a Website or application that combines the content from more than one source into an integrated presentation...
Dechanneling by dislocation loops
International Nuclear Information System (INIS)
Chalant, Gerard.
1976-09-01
Ion implantation always induces the creation of dislocation loops. When the damage profile is determined by a backscattering technique, the dechanneling by these loops is implicitely at the origin of these measurements. The dechanneling of alpha particles by dislocation loops produced by the coalescence of quenched-in vacancies in aluminium is studied. The dechanneling and the concentration of loops were determined simultaneously. The dechanneling width around dislocation was found equal to lambda=6A, both for perfect and imperfect loops having a mean diameter d=250A. In the latter case, a dechanneling probability chi=0.34 was determined for the stacking fault, in good agreement with previous determination in gold. A general formula is proposed which takes into account the variation of lambda with the curvature (or the diameter d) of the loops. Finally, by a series of isothermal anneals, the self-diffusion energy ΔH of aluminium was measured. The value obtained ΔH=1.32+-0.10eV is in good agreement with the values obtained by other methods [fr
Looping in OLSRv2 in Mobile Ad-Hoc Networks, Loop Suppression and Loop Correction
Speakman, Lee; Owada, Yasunori; Mase, Kenichi
Transient routing loops have been observed to form in Mobile Ad-hoc Networks running the OLSRv2 proactive link-state routing protocol. The packets falling into loops impact the surrounding network thus degrading throughput even though only a small proportion of the traffic may enter these loops and only for a short time. This becomes significantly more evident when Link Layer Notification is used to catch broken links, inadvertently leading to an increase in the number of loops. Two methods of Loop Detection are introduced and are used to trigger either Loop Suppression by selectively and preemptively discarding the looping packets that are unlikely to reach their destination, or Loop Correction by the notification of the routing protocol to cut the link over which the packet is looping. The newly introduced Loop Suppression and Loop Correction techniques used with Link Layer Notification are shown to significantly increase network performance over plain OLSRv2 and OLSRv2 with Link Layer Notification.
Outcome and development of symptoms after orthotopic liver transplantation for Wilson disease.
Weiss, Karl Heinz; Schäfer, Mark; Gotthardt, Daniel Nils; Angerer, Alexandra; Mogler, Carolin; Schirmacher, Peter; Schemmer, Peter; Stremmel, Wolfgang; Sauer, Peter
2013-01-01
Wilson disease (WD) is an autosomal recessive copper storage disease resulting in hepatic and neurologic dysfunction. Liver transplantation is an effective treatment for fulminant cases for patients with chronic liver disease. Reports on the outcome of neuropsychiatric symptoms after orthotopic liver transplantation (OLT) are limited. To assess the course of neuropsychiatric and hepatic symptoms after liver transplantation for Wilson disease Nineteen patients with Wilson disease received liver transplantation and were followed prospectively from 2005 to 2010 for the development of hepatic, neurological and psychiatric symptoms. Eight patients (all female) were transplanted for acute liver failure and eleven patients for chronic liver failure. Patient survival rates one and five yr after transplantation were 78% and 65%, respectively. Of the surviving patients, hepatic symptom scores improved in all patients and neurological symptom scores improved in all but one patient after OLT compared to the time of initial diagnosis and compared to pre-OLT status. Psychiatric symptoms showed moderate improvements. Survival after OLT for Wilson disease with end-stage liver disease is excellent. Overall, neuropsychiatric symptoms improved after transplantation, substantiating arguments for widening of the indication for liver transplantation in symptomatic neurologic Wilson disease patients with stable liver function. © 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
Mixed heavy-light matching in the Universal One-Loop Effective Action
Ellis, Sebastian A. R.; Quevillon, Jérémie; You, Tevong; Zhang, Zhengkang
2016-11-01
Recently, a general result for evaluating the path integral at one loop was obtained in the form of the Universal One-Loop Effective Action. It may be used to derive effective field theory operators of dimensions up to six, by evaluating the traces of matrices in this expression, with the mass dependence encapsulated in the universal coefficients. Here we show that it can account for loops of mixed heavy-light particles in the matching procedure. Our prescription for computing these mixed contributions to the Wilson coefficients is conceptually simple. Moreover it has the advantage of maintaining the universal structure of the effective action, which we illustrate using the example of integrating out a heavy electroweak triplet scalar coupling to a light Higgs doublet. Finally we also identify new structures that were previously neglected in the universal results.
Mixed heavy–light matching in the Universal One-Loop Effective Action
International Nuclear Information System (INIS)
Ellis, Sebastian A.R.; Quevillon, Jérémie; You, Tevong; Zhang, Zhengkang
2016-01-01
Recently, a general result for evaluating the path integral at one loop was obtained in the form of the Universal One-Loop Effective Action. It may be used to derive effective field theory operators of dimensions up to six, by evaluating the traces of matrices in this expression, with the mass dependence encapsulated in the universal coefficients. Here we show that it can account for loops of mixed heavy–light particles in the matching procedure. Our prescription for computing these mixed contributions to the Wilson coefficients is conceptually simple. Moreover it has the advantage of maintaining the universal structure of the effective action, which we illustrate using the example of integrating out a heavy electroweak triplet scalar coupling to a light Higgs doublet. Finally we also identify new structures that were previously neglected in the universal results.
Mixed heavy–light matching in the Universal One-Loop Effective Action
Energy Technology Data Exchange (ETDEWEB)
Ellis, Sebastian A.R. [Michigan Center for Theoretical Physics (MCTP), Department of Physics, University of Michigan, Ann Arbor, MI 48109 (United States); Quevillon, Jérémie [Theoretical Particle Physics and Cosmology Group, Physics Department, King' s College London, London WC2R 2LS (United Kingdom); You, Tevong [DAMTP, University of Cambridge, Wilberforce Road, Cambridge, CB3 0WA (United Kingdom); Cavendish Laboratory, University of Cambridge, J.J. Thomson Avenue, Cambridge, CB3 0HE (United Kingdom); Zhang, Zhengkang, E-mail: zzkevin@umich.edu [Michigan Center for Theoretical Physics (MCTP), Department of Physics, University of Michigan, Ann Arbor, MI 48109 (United States)
2016-11-10
Recently, a general result for evaluating the path integral at one loop was obtained in the form of the Universal One-Loop Effective Action. It may be used to derive effective field theory operators of dimensions up to six, by evaluating the traces of matrices in this expression, with the mass dependence encapsulated in the universal coefficients. Here we show that it can account for loops of mixed heavy–light particles in the matching procedure. Our prescription for computing these mixed contributions to the Wilson coefficients is conceptually simple. Moreover it has the advantage of maintaining the universal structure of the effective action, which we illustrate using the example of integrating out a heavy electroweak triplet scalar coupling to a light Higgs doublet. Finally we also identify new structures that were previously neglected in the universal results.
X-ray studies of irradiation induced dislocation loops in metals
International Nuclear Information System (INIS)
Larson, B.C.
1975-01-01
Theoretical and experimental progress has resulted in the increased use of x-rays for the study of defects and defect clusters in crystals. An outline of the theoretical framework associated with Huang, Stokes-Wilson and integral diffuse scattering from dislocation loops is presented, and an account of recent experiments on radiation induced loops is given. These studies include low temperature, ambient temperature, and elevated temperature irradiations of metals with electrons, neutrons, and accelerated ions, and pertain to the study of the thermal annealing characteristics as well as the as-produced damage structure. The information obtained by x-rays as to the type, size and concentrations of dislocation loops is contrasted with existing electron microscopy, electrical resistivity, and lattice parameter data in order to establish correlations and identify areas of disagreement
Energy Technology Data Exchange (ETDEWEB)
Lee, Gil-yong; Jung, Min-kyung; Ryoo, Sung-nam; Ha, Sam-chul [Digital Appliance R and D, LG Electronics, Seoul 153-801 (Korea, Republic of); Park, Myung-seok [LG Solar Energy, Seoul 150-721 (Korea, Republic of); Kim, Sunhoe [Department of New Energy and Resource Engineering, Sangji University, Wonju, Gangwon 220-702 (Korea, Republic of)
2010-12-15
In order to satisfy the demands of customers, cost innovation of fuel cell systems is required for the commercialization of the fuel cell. Since the stack is one of the most expensive parts in a fuel cell system, cost reduction of stack is required for fuel cell commercialization. For this effort stainless steel 304 sheets were etched for the flow field and then coated for corrosion resistance. This enables the development of highly cost-effective bipolar plates (BPs) for a Proton Exchange Membrane Fuel Cell (PEMFC) stack of a 1 kW-class for Residential Power Generator (RPG). LG Electronics (LGE) developed a metal stack of 64 cells with the developed BPs and achieved a performance rating of 0.75 V/cell at 200 mA/cm{sup 2}. LGE also achieved a stack volume reduction of 20% compared to a stack of the same specifications consisting of graphite material BPs. The volume decrease can be represented as a cost reduction. LGE achieved the very low cost innovation to 1 USD per cell with cells developed from etched metal BPs. LGE also achieved 500 h of operation with LGE's RPG system; this test is still ongoing. The degradation rate of the stack was 27 {mu}V/hr. The end of life of the stack was estimated at approximately 17,000 h. (author)
Wine, Jennifer; Cominole, Melissa; Wheeless, Sarah; Bryant, Alyssa; Gilligan, Theresa; Dudley, Kristin; Franklin, Jeff
2006-01-01
The 2004/06 Beginning Postsecondary Students Longitudinal Study (BPS:04/06), conducted for the U.S. Department of Education's National Center for Education Statistics (NCES), collected information about the education and employment experiences of students in the two years following their first enrollment in postsecondary education. The primary…
International Nuclear Information System (INIS)
Walter, M.G.A.
2004-02-01
We consider several examples of a special class of heterotic compactifications, i.e. heterotic E 8 x E 8 orbifolds with Wilson line backgrounds. By developing a local perspective we show that a brane world like picture emerges. As an important result we prove that the local massless spectrum at such a brane can always be traced back to the global spectrum of a (different) orbifold without Wilson lines. One particular implication of this result is that the use of (discrete) Wilson lines for the construction of phenomenologically interesting models has to be rethought. We show that stringy constraints render the brane spectra consistent. Using our local picture we are able to compute the local anomalies appearing at the different branes for our examples and show that they can all be cancelled by a local version of the Green-Schwarz mechanism at the same time. (orig.)
Kanter, Gregory; Volpe, Katherine A; Dunivan, Gena C; Cichowski, Sara B; Jeppson, Peter C; Rogers, Rebecca G; Komesu, Yuko M
2017-02-01
Interstitial cystitis/bladder pain syndrome (IC/BPS) is a poorly understood source of chronic pain causing significant morbidity, with variable treatment success. Despite the need to understand patient perspectives in chronic pain, there is a paucity of qualitative data for IC/BPS. We aimed to acquire information regarding patient experience with IC/BPS symptoms and with their medical care to elicit suggestions to improve patient satisfaction with that care. Fifteen women with IC/PBS participated in a total of four focus groups. Sessions were recorded and transcribed and information deidentified. Focus groups were conducted until thematic saturation was reached. All transcripts were coded and analyzed by a minimum of three independent physician reviewers. Investigators identified emergent themes and concepts using grounded-theory methodology. Participant's mean age was 52.6 years, with an average IC/BPS duration of 6.3 years. Thematic saturation was reached after four focus groups. We identified three emergent patient experience concepts: IC/PBS is debilitating, the disease course is unpredictable and unrelenting, and patients experience significant isolation. Importantly, suicidal ideation was expressed in each group. Patients voiced strong preference for physicians who provided education regarding the condition, an array of treatment options, organized treatment plans, and optimism and hope regarding treatment outcomes. Our study presents novel findings of the importance of patient-physician interaction in IC/BPS and reinforces the tremendous disability and burden of this disease, which frequently manifests in suicidal ideation. Patients preferred organized treatment plans with diverse choices and providers who offered hope in dealing with their condition.
The value-adding CFO: an interview with Disney's Gary Wilson. Interview by Geraldine E. Willigan.
Wilson, G
1990-01-01
Financing a company is more complex than ever-and more important to its economic success. The demands on a CFO are tremendous. Optimizing capital costs requires an unprecedented level of technical sophistication. Yet the best CFOs today are not mere technicians. They are also strategists and innovators. Gary Wilson exemplifies the new CFO. In his 5 years as executive vice president and CFO of the Walt Disney Company and his 12 years at Marriott Corporation, he has shown how the finance function can add value-not just account for it. How does a CFO create value for shareholders? "Just like all the great marketing and operating executives," Wilson says, "by being creative." To Wilson, being creative means rethinking assumptions and finding clever ways to achieve financial and strategic goals. Some of Wilson's innovative deal making-like the off-balance-sheet financing he used at Marriott-is well known. At Marriott, he discovered the power of separating the ownership of an asset from its control. Marriott's strength was in operations, yet the company had a great deal of money tied up in real estate. Growth would require even more investment in real estate. Wilson's solution was to sell the hotels-in effect, removing them and the debt used to finance them from the balance sheet-and contract to operate them. In this interview, Wilson gives his view of the role of finance in today's corporation and explains the thinking behind some of the successful deals he has engineered-including Disney's Silver Screen movie-making partnerships and Euro Disneyland.
Directory of Open Access Journals (Sweden)
Mehri Najafi
2014-09-01
Full Text Available Introduction: The Wilson disease is an autosomal recessive disease in which the liver, central nervous system, eyes, blood and other parts of the body involved. Timely diagnosis and appropriate treatment of the disease requires awareness of the clinical presentations of this disease in children.Methods: This case series study included 62 patients with Wilson disease who admitted to children's Medical Center in the years 2012-2003.Results: 56% of patients were male. The average age of diagnosis was 9.73 years old (5-17 years and this was higher in patients with early neurologic symptoms (P = 0.85.( 64.5% of the patients had the hepatic symptoms at the time of diagnosis and the most common type of hepatic involvement was cirrhosis (39.3% and hepatitis (17.5% respectively. 17.7% of the patients also had early neurological symptoms. A positive family history for the Wilson Disease were found in 27.4% of patients. 74.2% of patients had KF ring and the frequency of these symptom was higher in patients with early neurological involvement. 83.9% of patients were treated successfully with D-penicillamine and In 30% of patients, adverse drug reactions were seen.Conclusion: Children with unknown liver disease should be evaluated for Wilson disease and the first-degree relatives of patients should be screened. . D-penicillamine have important side effects, but due to the low cost and the availability is an appropriate drug to treat the Wilson disease..Key words: Wilson Disease, Hepatic Involvement, Neurologic Involvement , KF ring ,D-Penicillamine.
La maladie de Wilson chez l'enfant: à propos de 20 cas | Idrissi | Pan ...
African Journals Online (AJOL)
La maladie de Wilson ou dégénérescence hépato-lenticulaire est une affection génétique autosomique récessive caractérisée par une accumulation toxique de ... Nous avons réalisé une étude rétrospective portant sur 20 cas de maladie de Wilson colligés au sein du service de pédiatrie du CHU HASSAN II de Fès sur une ...
Making Moral Judgments from a World-Historic Standpoint: The Case of Woodrow Wilson.
Fuller, Steve
This comment reflects on the recent row over Woodrow Wilson's legacy, which has focussed on his undeniable racism. This was in pursuit of a 'Progressive' agenda which paved the way for the United States to become the geopolitical force that it continues to be today. Without necessarily approving of Wilson's particular judgements, I argue that he operated with a 'world-historic' sense of morality characteristic of Realpolitik , a perspective which might be worth considering by those who believe that modern preoccupations with 'race', 'class' and 'gender' will remain part of the sociological firmament indefinitely.ᅟ.
Kiraz, A; Aldemir, O; Karabulut, Y; Turan, C; Dundar, M
2013-01-01
Mowat-Wilson syndrome is a genetic disease characterized by typical facial features, Hirschsprung disease and multiple congenital abnormalities. MWS is a single gene disorder. One of the most specific clinical signs in MWS is the distinctive face. We report a two-year-old boy with multiple congenital anomalies. He had peripupillary atrophy and gingival hypertrophy different from the literature. The patient was also diagnosed with his clinical findings. These features may be important in Mowat-Wilson syndrome and clinicians should keep these findings in mind.
Vision to Reality: From Robert R. Wilson's Frontier to Leon M. Lederman's Fermilab
Hoddeson, Lilian; Kolb, Adrienne
We examine the roles of vision and leadership in creating and directing Fermi National Accelerator Laboratory from the late 1960s through the 1980s. The story divides into two administrations having different problems and accomplishments, that of Robert R. Wilson from 1967-1978, which saw the transformation from cornfield to frontier physics facility, and that of Leon M. Lederman from 1979-1989, in which the laboratory evolved into one of the world's major high-energy facilities. Lederman's pragmatic vision of a user-based experimental community helped him to convert the pioneering facility that Wilson had built frugally into a laboratory with a stable scientific, cultural, and funding environment.
A history of altruism focusing on Darwin, Allee and E.O. Wilson.
Domondon, Andrew T
2013-06-01
The problem of altruism refers to the apparent difficulty in reconciling the existence of altruists, individuals who reduce their own fitness to increase the fitness of others, with natural selection. A historical and philosophical overview of solutions to this apparent contradiction is presented through a close reading of the key texts of Charles Darwin, Warder C. Allee and Edward O. Wilson. Following an analysis of Darwin's explanation for altruism, I examine the ideas of group selection and kin selection advanced by Allee and Wilson, respectively, Attention is also given to the philosophical implications each associated with their respective solutions. Copyright © 2013 Elsevier Ltd. All rights reserved.
Partially quenched lattice QCD with two degenerate dynamical light Wilson quarks
International Nuclear Information System (INIS)
De, Asit K.; Harindranath, A.; Maiti, Jyotirmoy
2006-01-01
We present our results of numerical studies of partially quenched latticed QCD with two degenerate flavors of dynamical quarks. Gauge configurations are generated with Wilson gauge action and tadpole improved Wilson fermions at β = 5.6 and K sea = 0.155, 0.156, 0.157 and 0.158. Suitably smeared gauge configurations are used to calculate the static interquark potential in order to set the physical scale. Mesonic propagators are calculated at above mentioned four different values of K val for each K sea . We present results for pion and rho masses. (author)
Parton densities in quantum chromodynamics. Gauge invariance, path-dependence, and Wilson lines
Energy Technology Data Exchange (ETDEWEB)
Cherednikov, Igor O. [Antwerpen Univ. (Belgium). Dept. Fysica; Veken, Frederik F. van der [CERN, Geneva (Switzerland)
2017-05-01
The purpose of this book is to give a systematic pedagogical exposition of the quantitative analysis of Wilson lines and gauge-invariant correlation functions in quantum chromodynamics. Using techniques from the previous volume (Wilson Lines in Quantum Field Theory, 2014), an ab initio methodology is developed and practical tools for its implementation are presented. Emphasis is put on the implications of gauge invariance and path-dependence properties of transverse-momentum dependent parton density functions. The latter are associated with the QCD factorization approach to semi-inclusive hadronic processes, studied at currently operating and planned experimental facilities.
DEFF Research Database (Denmark)
Prosman, Ernst-Jan; Wæhrens, Brian Vejrum; Liotta, Giacomo
2017-01-01
Replacing virgin materials with waste materials, a practice known as Industrial Symbiosis (IS), has been identified as a key strategy for closing material loops. This article adopts a critical view on geographic proximity and external coordinators – two key enablers of IS. By ‘uncovering’ a case ...... for geographic proximity and external coordinators. In doing so, our insights into firm-level challenges of long-distance IS exchanges contribute to closing global material loops by increasing the number of potential circular pathways....
Closed Loop Subspace Identification
Directory of Open Access Journals (Sweden)
Geir W. Nilsen
2005-07-01
Full Text Available A new three step closed loop subspace identifications algorithm based on an already existing algorithm and the Kalman filter properties is presented. The Kalman filter contains noise free states which implies that the states and innovation are uneorre lated. The idea is that a Kalman filter found by a good subspace identification algorithm will give an output which is sufficiently uncorrelated with the noise on the output of the actual process. Using feedback from the output of the estimated Kalman filter in the closed loop system a subspace identification algorithm can be used to estimate an unbiased model.
Directory of Open Access Journals (Sweden)
Rovelli Carlo
1998-01-01
Full Text Available The problem of finding the quantum theory of the gravitational field, and thus understanding what is quantum spacetime, is still open. One of the most active of the current approaches is loop quantum gravity. Loop quantum gravity is a mathematically well-defined, non-perturbative and background independent quantization of general relativity, with its conventional matter couplings. Research in loop quantum gravity today forms a vast area, ranging from mathematical foundations to physical applications. Among the most significant results obtained are: (i The computation of the physical spectra of geometrical quantities such as area and volume, which yields quantitative predictions on Planck-scale physics. (ii A derivation of the Bekenstein-Hawking black hole entropy formula. (iii An intriguing physical picture of the microstructure of quantum physical space, characterized by a polymer-like Planck scale discreteness. This discreteness emerges naturally from the quantum theory and provides a mathematically well-defined realization of Wheeler's intuition of a spacetime ``foam''. Long standing open problems within the approach (lack of a scalar product, over-completeness of the loop basis, implementation of reality conditions have been fully solved. The weak part of the approach is the treatment of the dynamics: at present there exist several proposals, which are intensely debated. Here, I provide a general overview of ideas, techniques, results and open problems of this candidate theory of quantum gravity, and a guide to the relevant literature.
Justification by Infinite Loops
Peijnenburg, A.J.M.; Atkinson, David
2010-01-01
In an earlier paper we have shown that a proposition can have a well-defined probability value, even if its justification consists of an infinite linear chain. In the present paper we demonstrate that the same holds if the justification takes the form of a closed loop. Moreover, in the limit that
Improving Loop Dependence Analysis
DEFF Research Database (Denmark)
Jensen, Nicklas Bo; Karlsson, Sven
2017-01-01
Programmers can no longer depend on new processors to have significantly improved single-thread performance. Instead, gains have to come from other sources such as the compiler and its optimization passes. Advanced passes make use of information on the dependencies related to loops. We improve th...
2010-10-01
... rails, woodcock, and common (Wilson's) snipe. 20.104 Section 20.104 Wildlife and Fisheries UNITED STATES... for rails, woodcock, and common (Wilson's) snipe. This section provides for the annual hunting of certain rails, woodcock, and snipe in the 48 contiguous United States. [44 FR 7148, Feb. 6, 1979...
Face of the giant panda sign in Wilson disease | Chakraborty | SA ...
African Journals Online (AJOL)
Wilson disease usually presents with neurological or hepatic manifestations. Magnetic resonance imaging (MRI) of the brain is most informative in diagnosing this disease, especially in patients with neurological features. High T2 signal intensity in the corpus striatum is the most commonly encountered MRI finding. The 'face ...
2002-01-01
Helen Edwards has been awarded the 2003 Robert R. Wilson prize. She was cited for "her pivotal achievement and critical contribution as the leader in the design, construction, commissioning and operation of the Tevatron, and for her continued contributions to the development of high gradient superconducting linear accelerators as well as bright and intense electron sources." (1/2 page).
Symmetry analysis and conservation laws of the Drinfeld-Sokolov-Wilson system
Zhao, Zhonglong; Zhang, Yufeng; Han, Zhong
2014-07-01
In this paper, Lie symmetry analysis is performed on the Drinfeld-Sokolov-Wilson system. We get the corresponding Lie algebra and similarity reductions of the system. In addition, we utilize Noether's approach and the new conservation theorem deriving the conservation laws of this system.
Exact solutions of the Drinfel'd–Sokolov–Wilson equation using ...
Indian Academy of Sciences (India)
ber of powerful and efficient methods, such as trial equation method [1,2], multiple exp-function method [3], extended tanh method [4], (G /G)-expansion method [5], trans- formed rational function method [6,7] etc. have been developed by those scientists. The. Drinfel'd–Sokolov–Wilson equation (DSWE) that is to be studied ...
Comments on ''Geomagnetic response to magnetic clouds'' by Robert M. Wilson; and reply
International Nuclear Information System (INIS)
Gonzalez, W.D.; Gonzalez, A.L.C.; Wilson, R.M.
1988-01-01
The paper 'Geomagnetic Response to Magnetic Clouds' by Wilson (1987) tried to show an association between geomagnetic storm intervals and the passage of interplanetary magnetic clouds at the Earth's magnetosphere. The association is shown through a superposed epoch analysis of the interplanetary magnetic field (IMF)-B Z component and the D st geomagnetic storm index for 19 cloud events occurring between 1973 and 1978. Two aspects of the magnetic cloud-storm relationship are challenged. The first concerns the northward-southward rotation of the IMF-B Z component which is known to exist but not accounted for in Wilson's article. The second concerns the magnitude of the storms associated with the passage of magnetic clouds. In a reply Wilson explains the distinction between N-turning and S-turning clouds of the 19 clouds studied 12 were southward and 7 northward turning. The average behaviour of both is similar, the differences being due to the different onset values of D st . The second problem is attributed to a misunderstanding of the meaning of the I-bars given in the original article. The original results of Wilson are reaffirmed. The comment on the reply suggests that the average peak D st value for S-N clouds is larger by 30% than for the N-S clouds and that the final intensity of the storm can be altered by the type of cloud involved (S-N) or (N-S). (U.K.)
An anisotropic preconditioning for the Wilson fermion matrix on the lattice
International Nuclear Information System (INIS)
Joo, Balint; Edwards, Robert G; Peardon, Michael
2010-01-01
A preconditioning for the Wilson fermion matrix on the lattice is defined, which is particularly suited to the case when the temporal lattice spacing is much smaller than the spatial one. Details on the implementation of the scheme are given. The method is tested in numerical studies of quantum chromodynamics on anisotropic lattices.
Directory of Open Access Journals (Sweden)
Desplanches H.
2006-11-01
Full Text Available Un programme de calcul des paramètres de l'équation de Wilson est mis au point. II utilise une méthode itérative de minimisation des écarts sur la pression et la composition de vapeur ou sur chaque grandeur prise séparément. Les méthodes utilisées sont testées sur neuf équilibres liquide-vapeur isothermes de mélanges binaires à déviations positives ou négatives. Les écarts moyens entre les valeurs expérimentales : - de la pression; - de la composition de la vapeur; - de l'enthalpie libre d'excès; et les valeurs calculées à partir des paramètres de Wilson sont comparés à ceux obtenus d'après le modèle NRTL. A program has been developed for computing the parameters in the Wilson equation. It uses an iterative method of minimizing the differences in pressure and steam composition or in each magnitude token separately. The methods used are tried out on nine isothermal liquid-vapor equilibria of binary mixtures with positive or negative deviations. The mean differences between experimental values of the : - pressure; - vapor composition; - excess free enthalpy; and values computed from Wilson parameters are compared with those obtained from an NRTL model.
Linda S. DeLay; Deborah M. Finch; Sandra Brantley; Richard Fagerlund; Michael D. Means; Jeffrey F. Kelly
1999-01-01
We compared abundance of migrating Willow Flycatchers and Wilson's Warblers to the abundance of arthropods in exotic and native vegetation at Bosque del Apache National Wildlife Refuge. We trapped arthropods using glue-boards in 1996 and 1997 in the same cottonwood, saltcedar, and willow habitats where we mist-netted birds during spring and fall migration. There...
Insights into Wilson's Warbler migration from analyses of hydrogen stable-isotope ratios
Jeffrey F. Kelly; Viorel Atudorei; Zachary D. Sharp; Deborah M. Finch
2002-01-01
Our ability to link the breeding locations of individual passerines to migration stopover sites and wintering locations is limited. Stable isotopes of hydrogen contained in bird feathers have recently shown potential in this regard. We measured hydrogen stable-isotope ratios (deltaD) of feathers from breeding, migrating, and wintering Wilson's Warblers. Analyses...
The Development of Field Guides for Birding: Gwillim, Wilson, Audubon and Peterson.
Cameron, Teddy
2000-01-01
Discusses the increasing interest of the public in nature and art of the 18th and 19th centuries, and making watercolor painting a part of the curriculum. Focuses on the works and publishing of Gwillim, Wilson, Audubon, and Peterson. (Contains 12 references.) (YDS)
Converting the H. W. Wilson Company Indexes to an Automated System: A Functional Analysis.
Regazzi, John J.
1984-01-01
Description of the computerized information system that supports the editorial and manufacturing processes involved in creation of Wilson's subject indexes and catalogs includes the major subsystems--online data entry, batch input processing, validation and release, file generation and database management, online and offline retrieval, publication…
Psychological Evidence in Larry P. v Wilson Riles: An Evaluation by a Witness for the Defense.
Lambert, Nadine M.
1981-01-01
Presents a history and analysis of the Larry P. v Wilson Riles litigation in California which prohibited the use of intelligence tests for determining eligibility of Black children for placement in educable mentally retarded programs. Argues against the court decision, and claims tests are not biased. (APM)
Anatomy of One-Loop Effective Action in Noncommutative Scalar Field Theories
Kiem, Youngjai; Sato, Haru-Tada; Yee, Jung-Tay; Kiem, Youngjai; Rey, Soo-Jong; Sato, Haru-Tada; Yee, Jung-Tay
2002-01-01
One-loop effective action of noncommutative scalar field theory with cubic self-interaction is studied. Utilizing worldline formulation, both planar and nonplanar part of the effective action are computed explicitly. We find complete agreement of the result with Seiberg-Witten limit of string worldsheet computation and standard Feynman diagrammatics. We prove that, at low-energy and large noncommutativity limit, nonplanar part of the effective action is simplified enormously and is resummable into a quadratic action of scalar open Wilson line operators.
Urban research in a hostile setting: Godfrey Wilson in Broken Hill, Northern Rhodesia, 1938-1940
Directory of Open Access Journals (Sweden)
Karen Tranberg Hansen
Full Text Available Acknowledged for his pioneering urban anthropological research in Broken Hill through the publication of An Essay on the Economics of Detribalization in Northern Rhodesia (Parts I and II, 1940 and 1941, Godfrey Wilson's professional career was cut short by his death during World War II. The late 1990s transfer and cataloguing at the University of Cape Town of the Monica and Godfrey Wilson papers has made an enormously rich research archive accessible to the public. For the first time, Godfrey Wilson's notes from his fieldwork in Broken Hill enable us to examine his research project through his own observations. Based on a preliminary overview of these records and a tentative analysis of some of their contents, this article revisits the Broken Hill research project against the background of the published essay on the economics of detribalisation. Wilson's argument about temporary urbanisation is demonstrated through migration histories, information about length of stay in towns, and an analysis of the economics of urban livelihoods that focuses on wages including rations, household expenditures, and urban-rural transfers. But the published essay barely explains how in fact he conducted his field research. Although there are very few direct indications, we can infer some of his fieldwork practices and field methodology from notes that occasionally evoke an immediate sense of the trials and tribulations of everyday African life in Broken Hill in the early World War II years. How might experiences in the field have influenced Wilson's analysis? Overall, I discuss his work from two angles, first in the context of a time and place characterised by conflicting agendas, and secondly, in retrospect as the conceptual space and time of early World War II colonial Northern Rhodesia have yielded to different explanatory perspectives.
Hoke, Tanya P; Goldstein, Howard; Saks, Emily K; Vakili, Babak
2017-03-01
The purpose of this study is to determine whether a transvaginal trigonal block immediately preceding cystoscopy with hydrodistention yields an additional therapeutic benefit compared to cystoscopy with hydrodistention alone for the treatment of bladder pain syndrome/interstitial cystitis (BPS/IC). A retrospective chart review was performed at a single-center. Performance of a trigonal block prior to hydrodistention was at the discretion of the surgeon. A trigonal block consists of injecting 0.25% bupivacaine with 1.0% Xylocaine into the anterior vagina under the trigone under cystoscopic guidance. Procedures between January 1, 2008 and December 31, 2013 were included. The primary outcome compared change in pain score from the baseline to 1-month post-operative. One hundred and eighty-three patients underwent hydrodistention of the bladder. Seventy-seven were excluded and of the 106 patients remaining, 48 received a trigonal block and 58 did not. Both groups had a significant improvement in pain scores (P 5 min based on surgeon preference. There was no difference in change in pain score from baseline between both groups (-3.0 vs. -2.2; P = 0.061). Hydrodistention of the bladder decreased pain postoperatively regardless of trigonal block or time of distention. A randomized-controlled trial is necessary to determine the benefits of duration of hydrodistention or performance of a block. Neurourol. Urodynam. 36:784-786, 2017. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.
Ototoxicity of loop diuretics.
Rybak, L P
1993-10-01
The loop diuretics are drugs that increase the excretion of water and electrolytes in the urine by their action on the cells in the loop of Henle. Clinical reports of ototoxicity of these agents are reviewed, and the results of a number of studies in experimental animals are discussed. These drugs can cause either a temporary, or in some cases, a permanent loss of hearing in patients. Animal experiments show that these drugs act on the stria vascularis, producing edema of these tissues and a temporary loss of function, resulting in a decrease of the endocochlear potential. This can result in secondary effects on sound-evoked measures of hearing. As new information unfolds about protective agents, it may be possible to preserve hearing and maintain the desired therapeutic effect.
Directory of Open Access Journals (Sweden)
Bojowald Martin
2008-07-01
Full Text Available Quantum gravity is expected to be necessary in order to understand situations in which classical general relativity breaks down. In particular in cosmology one has to deal with initial singularities, i.e., the fact that the backward evolution of a classical spacetime inevitably comes to an end after a finite amount of proper time. This presents a breakdown of the classical picture and requires an extended theory for a meaningful description. Since small length scales and high curvatures are involved, quantum effects must play a role. Not only the singularity itself but also the surrounding spacetime is then modified. One particular theory is loop quantum cosmology, an application of loop quantum gravity to homogeneous systems, which removes classical singularities. Its implications can be studied at different levels. The main effects are introduced into effective classical equations, which allow one to avoid the interpretational problems of quantum theory. They give rise to new kinds of early-universe phenomenology with applications to inflation and cyclic models. To resolve classical singularities and to understand the structure of geometry around them, the quantum description is necessary. Classical evolution is then replaced by a difference equation for a wave function, which allows an extension of quantum spacetime beyond classical singularities. One main question is how these homogeneous scenarios are related to full loop quantum gravity, which can be dealt with at the level of distributional symmetric states. Finally, the new structure of spacetime arising in loop quantum gravity and its application to cosmology sheds light on more general issues, such as the nature of time.
Bojowald, Martin
2008-01-01
Quantum gravity is expected to be necessary in order to understand situations in which classical general relativity breaks down. In particular in cosmology one has to deal with initial singularities, i.e., the fact that the backward evolution of a classical spacetime inevitably comes to an end after a finite amount of proper time. This presents a breakdown of the classical picture and requires an extended theory for a meaningful description. Since small length scales and high curvatures are involved, quantum effects must play a role. Not only the singularity itself but also the surrounding spacetime is then modified. One particular theory is loop quantum cosmology, an application of loop quantum gravity to homogeneous systems, which removes classical singularities. Its implications can be studied at different levels. The main effects are introduced into effective classical equations, which allow one to avoid the interpretational problems of quantum theory. They give rise to new kinds of early-universe phenomenology with applications to inflation and cyclic models. To resolve classical singularities and to understand the structure of geometry around them, the quantum description is necessary. Classical evolution is then replaced by a difference equation for a wave function, which allows an extension of quantum spacetime beyond classical singularities. One main question is how these homogeneous scenarios are related to full loop quantum gravity, which can be dealt with at the level of distributional symmetric states. Finally, the new structure of spacetime arising in loop quantum gravity and its application to cosmology sheds light on more general issues, such as the nature of time. Supplementary material is available for this article at 10.12942/lrr-2008-4.
Dassau, E; Atlas, E; Phillip, M
2010-02-01
The dream of closing the loop is actually the dream of creating an artificial pancreas and freeing the patients from being involved with the care of their own diabetes. Insulin-dependent diabetes (type 1) is a chronic incurable disease which requires constant therapy without the possibility of any 'holidays' or insulin-free days. It means that patients have to inject insulin every day of their life, several times per day, and in order to do it safely they also have to measure their blood glucose levels several times per day. Patients need to plan their meals, their physical activities and their insulin regime - there is only very small room for spontaneous activities. This is why the desire for an artificial pancreas is so strong despite the fact that it will not cure the diabetic patients. Attempts to develop a closed-loop system started in the 1960s but never got to a clinical practical stage of development. In recent years the availability of continuous glucose sensors revived those efforts and stimulated the clinician and researchers to believe that closing the loop might be possible nowadays. Many papers have been published over the years describing several different ideas on how to close the loop. Most of the suggested systems have a sensing arm that measures the blood glucose repeatedly or continuously, an insulin delivery arm that injects insulin upon command and a computer that makes the decisions of when and how much insulin to deliver. The differences between the various published systems in the literature are mainly in their control algorithms. However, there are also differences related to the method and site of glucose measurement and insulin delivery. SC glucose measurements and insulin delivery are the most studied option but other combinations of insulin measurements and glucose delivery including intravascular and intraperitoneal (IP) are explored. We tried to select recent publications that we believe had influenced and inspired people interested
Directory of Open Access Journals (Sweden)
Bojowald Martin
2005-12-01
Full Text Available Quantum gravity is expected to be necessary in order to understand situations where classical general relativity breaks down. In particular in cosmology one has to deal with initial singularities, i.e., the fact that the backward evolution of a classical space-time inevitably comes to an end after a finite amount of proper time. This presents a breakdown of the classical picture and requires an extended theory for a meaningful description. Since small length scales and high curvatures are involved, quantum effects must play a role. Not only the singularity itself but also the surrounding space-time is then modified. One particular realization is loop quantum cosmology, an application of loop quantum gravity to homogeneous systems, which removes classical singularities. Its implications can be studied at different levels. Main effects are introduced into effective classical equations which allow to avoid interpretational problems of quantum theory. They give rise to new kinds of early universe phenomenology with applications to inflation and cyclic models. To resolve classical singularities and to understand the structure of geometry around them, the quantum description is necessary. Classical evolution is then replaced by a difference equation for a wave function which allows to extend space-time beyond classical singularities. One main question is how these homogeneous scenarios are related to full loop quantum gravity, which can be dealt with at the level of distributional symmetric states. Finally, the new structure of space-time arising in loop quantum gravity and its application to cosmology sheds new light on more general issues such as time.
LoopIng: a template-based tool for predicting the structure of protein loops.
Messih, Mario Abdel
2015-08-06
Predicting the structure of protein loops is very challenging, mainly because they are not necessarily subject to strong evolutionary pressure. This implies that, unlike the rest of the protein, standard homology modeling techniques are not very effective in modeling their structure. However, loops are often involved in protein function, hence inferring their structure is important for predicting protein structure as well as function.We describe a method, LoopIng, based on the Random Forest automated learning technique, which, given a target loop, selects a structural template for it from a database of loop candidates. Compared to the most recently available methods, LoopIng is able to achieve similar accuracy for short loops (4-10 residues) and significant enhancements for long loops (11-20 residues). The quality of the predictions is robust to errors that unavoidably affect the stem regions when these are modeled. The method returns a confidence score for the predicted template loops and has the advantage of being very fast (on average: 1 min/loop).www.biocomputing.it/loopinganna.tramontano@uniroma1.itSupplementary data are available at Bioinformatics online.
On some properties of conjugacy closed loops
International Nuclear Information System (INIS)
Adeniran, John Olusola
2002-07-01
It is shown that central loops are not conjugacy closed loops but instead are loops of units in their loop algebras that are conjugacy closed. It is also shown that certain inner mappings of a conjugacy closed loop are nuclear. Some invariants of left conjugacy closed loops are obtained. (author)
Hedgehog black holes and the Polyakov loop at strong coupling
Headrick, Matthew
2008-05-01
In N=4 super-Yang-Mills theory at large N, large λ, and finite temperature, the value of the Wilson-Maldacena loop wrapping the Euclidean time circle (the Polyakov-Maldacena loop, or PML) is computed by the area of a certain minimal surface in the dual supergravity background. This prescription can be used to calculate the free energy as a function of the PML (averaged over the spatial coordinates), by introducing into the bulk action a Lagrange multiplier term that fixes the (average) area of the appropriate minimal surface. This term, which can also be viewed as a chemical potential for the PML, contributes to the bulk stress tensor like a string stretching from the horizon to the boundary (smeared over the angular directions). We find the corresponding “hedgehog” black hole solutions numerically, within an SO(6)-preserving ansatz, and derive part of the free energy diagram for the PML. As a warm-up problem, we also find exact solutions for hedgehog black holes in pure gravity, and derive the free energy and phase diagrams for that system.
Remarks on non-BPS string amplitudes and their all order α{sup ′} contact interactions in IIB, IIA
Energy Technology Data Exchange (ETDEWEB)
Hatefi, Ehsan [Institute for Theoretical Physics, TU Wien,Wiedner Hauptstrasse 8-10/136, A-1040 Vienna (Austria)
2017-03-06
We explore the entire form of S-Matrix elements of a potential C{sub n−1} Ramond-Ramond (RR) form field, a tachyon and two transverse scalar fields on both world volume and transverse directions of type IIB and IIA superstring theories. Apart from
Iterative and iterative-noniterative integral solutions in 3-loop massive QCD calculations
International Nuclear Information System (INIS)
Ablinger, J.; Radu, C.S.; Schneider, C.; Behring, A.; Imamoglu, E.; Van Hoeij, M.; Von Manteuffel, A.; Raab, C.G.
2017-11-01
Various of the single scale quantities in massless and massive QCD up to 3-loop order can be expressed by iterative integrals over certain classes of alphabets, from the harmonic polylogarithms to root-valued alphabets. Examples are the anomalous dimensions to 3-loop order, the massless Wilson coefficients and also different massive operator matrix elements. Starting at 3-loop order, however, also other letters appear in the case of massive operator matrix elements, the so called iterative non-iterative integrals, which are related to solutions based on complete elliptic integrals or any other special function with an integral representation that is definite but not a Volterra-type integral. After outlining the formalism leading to iterative non-iterative integrals,we present examples for both of these cases with the 3-loop anomalous dimension γ (2) qg and the structure of the principle solution in the iterative non-interative case of the 3-loop QCD corrections to the ρ-parameter.
Extending the Universal One-Loop Effective Action: heavy-light coefficients
Ellis, Sebastian A. R.; Quevillon, Jérémie; You, Tevong; Zhang, Zhengkang
2017-08-01
The Universal One-Loop Effective Action (UOLEA) is a general expression for the effective action obtained by evaluating in a model-independent way the one-loop expansion of a functional path integral. It can be used to match UV theories to their low-energy EFTs more efficiently by avoiding redundant steps in the application of functional methods, simplifying the process of obtaining Wilson coefficients of operators up to dimension six. In addition to loops involving only heavy fields, matching may require the inclusion of loops containing both heavy and light particles. Here we use the recently-developed covariant diagram technique to extend the UOLEA to include heavy-light terms which retain the same universal structure as the previously-derived heavy-only terms. As an example of its application, we integrate out a heavy singlet scalar with a linear coupling to a light doublet Higgs. The extension presented here is a first step towards completing the UOLEA to incorporate all possible structures encountered in a covariant derivative expansion of the one-loop path integral.
Iterative and iterative-noniterative integral solutions in 3-loop massive QCD calculations
Energy Technology Data Exchange (ETDEWEB)
Ablinger, J.; Radu, C.S.; Schneider, C. [Johannes Kepler Univ., Linz (Austria). Research Inst. for Symbolic Computation (RISC); Behring, A. [RWTH Aachen Univ. (Germany). Inst. fuer Theoretische Teilchenphysik und Kosmologie; Bluemlein, J.; Freitas, A. de [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany); Imamoglu, E.; Van Hoeij, M. [Florida State Univ., Tallahassee, FL (United States). Dept. of Mathematics; Von Manteuffel, A. [Michigan State Univ., East Lansing, MI (United States). Dept. of Physics and Astronomy; Raab, C.G. [Johannes Kepler Univ., Linz (Austria). Inst. for Algebra
2017-11-15
Various of the single scale quantities in massless and massive QCD up to 3-loop order can be expressed by iterative integrals over certain classes of alphabets, from the harmonic polylogarithms to root-valued alphabets. Examples are the anomalous dimensions to 3-loop order, the massless Wilson coefficients and also different massive operator matrix elements. Starting at 3-loop order, however, also other letters appear in the case of massive operator matrix elements, the so called iterative non-iterative integrals, which are related to solutions based on complete elliptic integrals or any other special function with an integral representation that is definite but not a Volterra-type integral. After outlining the formalism leading to iterative non-iterative integrals,we present examples for both of these cases with the 3-loop anomalous dimension γ{sup (2)}{sub qg} and the structure of the principle solution in the iterative non-interative case of the 3-loop QCD corrections to the ρ-parameter.
New Constraints on Dark Matter Effective Theories from Standard Model Loops
Crivellin, Andreas; Procura, Massimiliano
2014-01-01
We consider an effective field theory for a gauge singlet Dirac dark matter (DM) particle interacting with the Standard Model (SM) fields via effective operators suppressed by the scale $\\Lambda \\gtrsim 1$ TeV. We perform a systematic analysis of the leading loop contributions to spin-independent (SI) DM--nucleon scattering using renormalization group evolution between $\\Lambda$ and the low-energy scale probed by direct detection experiments. We find that electroweak interactions induce operator mixings such that operators that are naively velocity-suppressed and spin-dependent can actually contribute to SI scattering. This allows us to put novel constraints on Wilson coefficients that were so far poorly bounded by direct detection. Constraints from current searches are comparable to LHC bounds, and will significantly improve in the near future. Interestingly, the loop contribution we find is maximally isospin violating even if the underlying theory is isospin conserving.
Revisiting the dilatation operator of the Wilson-Fisher fixed point
Liendo, Pedro
2017-07-01
We revisit the order-ε dilatation operator of the Wilson-Fisher fixed point obtained by Kehrein, Pismak, and Wegner in light of recent results in conformal field theory. Our approach is algebraic and based only on symmetry principles. The starting point of our analysis is that the first correction to the dilatation operator is a conformal invariant, which implies that its form is fixed up to an infinite set of coefficients associated with the scaling dimensions of higher-spin currents. These coefficients can be fixed using well-known perturbative results, however, they were recently re-obtained using CFT arguments without relying on perturbation theory. Our analysis then implies that all order-ε scaling dimensions of the Wilson-Fisher fixed point can be fixed by symmetry.
Simulating QCD at the physical point with Nf=2 Wilson twisted mass fermions at maximal twist
International Nuclear Information System (INIS)
Abdel-Rehim, A.; Alexandrou, C.; Cyprus Univ. Nicosia; Burger, F.
2015-12-01
We present simulations of QCD using N f =2 dynamical Wilson twisted mass lattice QCD with physical value of the pion mass and at one value of the lattice spacing. Such simulations at a∼0.09 fm became possible by adding the clover term to the action. While O(a) improvement is still guaranteed by Wilson twisted mass fermions at maximal twist, the introduction of the clover term reduces O(a 2 ) cutoff effects related to isospin symmetry breaking. We give results for a set of phenomenologically interesting observables like pseudo-scalar masses and decay constants, quark masses and the anomalous magnetic moments of leptons. We mostly find remarkably good agreement with phenomenology, even though we cannot take the continuum and thermodynamic limits.
Revisiting the dilatation operator of the Wilson-Fisher fixed point
Energy Technology Data Exchange (ETDEWEB)
Liendo, Pedro [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany). Theory Group
2017-01-15
We revisit the order ε dilatation operator of the Wilson-Fisher fixed point obtained by Kehrein, Pismak, and Wegner in light of recent results in conformal field theory. Our approach is algebraic and based only on symmetry principles. The starting point of our analysis is that the first correction to the dilatation operator is a conformal invariant, which implies that its form is fixed up to an infinite set of coefficients associated with the scaling dimensions of higher-spin currents. These coefficients can be fixed using well-known perturbative results, however, they were recently re-obtained using CFT arguments without relying on perturbation theory. Our analysis then implies that all order-ε scaling dimensions of the Wilson-Fisher fixed point can be fixed by symmetry.
Magnetic resonance imaging of the brain in Wilson's disease
Energy Technology Data Exchange (ETDEWEB)
Thuomas, K.AA. (Dept. of Diagnostic Radiology, Univ. Hospital, Uppsala (Sweden)); Aquilonius, S.M. (Dept. of Neurology, Univ. Hospital, Uppsala (Sweden)); Bergstroem, K. (Dept. of Diagnostic Radiology, Univ. Hospital, Uppsala (Sweden)); Westermark, K. (Dept. of Internal Medicine, Univ. Hospital, Uppsala (Sweden))
1993-02-01
Fifteen patients with Wilson's disease were examined, using spin-echo (SE) and gradient-echo (GE) sequences with 0.5 T and 1.5 T magnetic resonance (MR) imagers. They fell into three groups: groups 1 and 2 were examined retrospectively after 3-18 years of treatment, while group 3 was examined prospectively from the start of treatment, after recommencement of treatment, or inadequate treatment. MRI was sensitive to changes in the basal ganglia at sites typical of Wilson's disease and was useful for documenting the effects of treatment. It was found necessary to estimate the relaxation times T1 and T2, to better assess improvement or transient worsening of the disease in the prospective group. Residual cavitation and gliosis could be distinguished in the retrospective group using a subtraction technique. (orig.)
Eugene Onegin the Cold War Monument: How Edmund Wilson Quarreled with Vladimir Nabokov
Directory of Open Access Journals (Sweden)
Tim Conley
2014-01-01
Full Text Available The tale of how Edmund Wilson quarreled with Vladimir Nabokov over the latter’s 1964 translation of Eugene Onegin can be instructively read as a politically charged event, specifically a “high culture” allegory of the Cold War. Dissemination of anti-Communist ideals (often in liberal and literary guises was the mandate of the Congress for Cultural Freedom, whose funding and editorial initiatives included the publication of both pre-Revolution Russian literature and, more notoriously, the journal Encounter (1953-1990, where Nabokov’s fiery “Reply” to Wilson appeared. This essay outlines the propaganda value of the Onegin debate within and to Cold War mythology.
Directory of Open Access Journals (Sweden)
J. Ablinger
2015-01-01
Full Text Available The pure singlet asymptotic heavy flavor corrections to 3-loop order for the deep-inelastic scattering structure function F2(x,Q2 and the corresponding transition matrix element AQq(3,PS in the variable flavor number scheme are computed. In Mellin-N space these inclusive quantities depend on generalized harmonic sums. We also recalculate the complete 3-loop pure singlet anomalous dimension for the first time. Numerical results for the Wilson coefficients, the operator matrix element and the contribution to the structure function F2(x,Q2 are presented.
Segment-based Eyring-Wilson viscosity model for polymer solutions
International Nuclear Information System (INIS)
Sadeghi, Rahmat
2005-01-01
A theory-based model is presented for correlating viscosity of polymer solutions and is based on the segment-based Eyring mixture viscosity model as well as the segment-based Wilson model for describing deviations from ideality. The model has been applied to several polymer solutions and the results show that it is reliable both for correlation and prediction of the viscosity of polymer solutions at different molar masses and temperature of the polymer
Determination of csw in Nf=3+1 lattice QCD with massive Wilson fermions
International Nuclear Information System (INIS)
Fritzsch, Patrick; Stollenwerk, Felix; Wolff, Ulli; Sommer, Rainer
2015-01-01
We develop a strategy for the non-perturbative determination of the O(a)-improvement coefficient c sw for Wilson fermions with massive sea quarks. The improvement condition is defined via the PCAC relation in the Schroedinger functional. It is imposed along a line of constant physics designed to be close to the correct mass of the charm quark. The numerical work uses the tree-level improved Luescher-Weisz gauge action in N f =3+1 Lattice QCD.
Biopolymer strategy for the treatment of Wilson´s disease
Czech Academy of Sciences Publication Activity Database
Vetrík, Miroslav; Mattová, J.; Macková, Hana; Kučka, Jan; Poučková, P.; Kukačková, Olivia; Brus, Jiří; Eigner-Henke, S.; Sedláček, Ondřej; Šefc, L.; Štěpánek, Petr; Hrubý, Martin
2018-01-01
Roč. 273, 10 March (2018), s. 131-138 ISSN 0168-3659 R&D Projects: GA ČR(CZ) GA16-02870S; GA MZd(CZ) NV15-25781A; GA MŠk(CZ) LM2015064; GA MŠk(CZ) LO1507 Institutional support: RVO:61389013 Keywords : Wilson's disease * copper chelators * biopolymers Subject RIV: CD - Macromolecular Chemistry OBOR OECD: Polymer science Impact factor: 7.786, year: 2016
From rifting to subduction: the role of inheritance in the Wilson Cycle
Beaussier, Stéphane; Gerya, Taras; Burg, Jean-Pierre
2017-04-01
The Wilson Cycle entails that oceans close and reopen. This cycle is a fundamental principle in plate tectonics, inferring continuity from divergence to convergence and that continental rifting takes place along former suture zones. This view questions the role of inherited structures at each stage of the Wilson Cycle. Using the 3D thermo-mechanical code, I3ELVIS (Gerya and Yuen 2007) we present a high-resolution continuous model of the Wilson cycle from continental rifting, breakup and oceanic spreading to convergence and spontaneous subduction initiation. Therefore, all lateral and longitudinal structures of the lithospheres are generated self-consistently and are consequences of the initial continental structure, tectono-magmatic inheritance and material rheology. In the models, subduction systematically initiates off-ridge and is controlled by the convergence-induced swelling of the ridge. Geometry and dynamics of the developing off-ridge subduction is controlled by four main factors: (1) the obliquity of the ridge with respect to the convergence direction; (2) fluid-induced weakening of the oceanic crust; (3) irregularity of ridge and margins inherited from rifting and spreading; (4) strain localization at transform faults formed during ocean floor spreading. Further convergence can lead to obduction of the oceanic crust and segments of ridge after the oceanic lithosphere is entrained into subduction. We show that the main parameters controlling the occurrence and geometry of obducted ophiolite are the convergence rate and the inherited structure of the passive margins and ridge. Our numerical experiments results show the essential role played by inheritance during the Wilson Cycle and are consistent with nature observations such as the tectonic history of the Oman subduction-obduction system. REFERENCES Gerya, T. V., and D. A. Yuen. 2007: "Robust Characteristics Method for Modelling Multiphase Visco-Elasto-Plastic Thermo-Mechanical Problems, Physics of the
Optical diameters of stars measured with the Mt. Wilson Mark III interferometer
International Nuclear Information System (INIS)
Simon, R.S.; Mozurkewich, D.; Johnston, K.J.; Gaume, R.; Hutter, D.J.; Bowers, P.F.; Colavita, M.M.; Shao, M.
1990-01-01
Reliable stellar angular diameters can now be determined using the Mark III Optical Interferometer located on Mt. Wilson, California. The Mark III is a Michelson Interferometer capable of measuring the interferometric fringe visibility for stars using interferometer baselines varying from 3 to 31.5 meters in length. Angular diameters measured with the Mark III Optical Interferometer are presented for 12 stars at wavelengths of 450 and 800 nm. 10 refs
Fermion bag approach to the sign problem in strongly coupled lattice QED with Wilson fermions
Chandrasekharan, Shailesh; Li, Anyi
2010-01-01
We explore the sign problem in strongly coupled lattice QED with one flavor of Wilson fermions in four dimensions using the fermion bag formulation. We construct rules to compute the weight of a fermion bag and show that even though the fermions are confined into bosons, fermion bags with negative weights do exist. By classifying fermion bags as either simple or complex, we find numerical evidence that complex bags with positive and negative weights come with almost equal probabilities and th...
High temperature storage loop :
Energy Technology Data Exchange (ETDEWEB)
Gill, David Dennis; Kolb, William J.
2013-07-01
A three year plan for thermal energy storage (TES) research was created at Sandia National Laboratories in the spring of 2012. This plan included a strategic goal of providing test capability for Sandia and for the nation in which to evaluate high temperature storage (>650ÀC) technology. The plan was to scope, design, and build a flow loop that would be compatible with a multitude of high temperature heat transfer/storage fluids. The High Temperature Storage Loop (HTSL) would be reconfigurable so that it was useful for not only storage testing, but also for high temperature receiver testing and high efficiency power cycle testing as well. In that way, HTSL was part of a much larger strategy for Sandia to provide a research and testing platform that would be integral for the evaluation of individual technologies funded under the SunShot program. DOEs SunShot program seeks to reduce the price of solar technologies to 6/kWhr to be cost competitive with carbon-based fuels. The HTSL project sought to provide evaluation capability for these SunShot supported technologies. This report includes the scoping, design, and budgetary costing aspects of this effort
Staircase tableaux, the asymmetric exclusion process, and Askey-Wilson polynomials.
Corteel, Sylvie; Williams, Lauren K
2010-04-13
We introduce some combinatorial objects called staircase tableaux, which have cardinality 4(n)n!, and connect them to both the asymmetric exclusion process (ASEP) and Askey-Wilson polynomials. The ASEP is a model from statistical mechanics introduced in the late 1960s, which describes a system of interacting particles hopping left and right on a one-dimensional lattice of n sites with open boundaries. It has been cited as a model for traffic flow and translation in protein synthesis. In its most general form, particles may enter and exit at the left with probabilities alpha and gamma, and they may exit and enter at the right with probabilities beta and delta. In the bulk, the probability of hopping left is q times the probability of hopping right. Our first result is a formula for the stationary distribution of the ASEP with all parameters general, in terms of staircase tableaux. Our second result is a formula for the moments of (the weight function of) Askey-Wilson polynomials, also in terms of staircase tableaux. Since the 1980s there has been a great deal of work giving combinatorial formulas for moments of classical orthogonal polynomials (e.g. Hermite, Charlier, Laguerre); among these polynomials, the Askey-Wilson polynomials are the most important, because they are at the top of the hierarchy of classical orthogonal polynomials.
Modeling of compact loop antennas
International Nuclear Information System (INIS)
Baity, F.W.
1987-01-01
A general compact loop antenna model which treats all elements of the antenna as lossy transmission lines has been developed. In addition to capacitively-tuned resonant double loop (RDL) antennas the model treats stub-tuned resonant double loop antennas. Calculations using the model have been compared with measurements on full-scale mockups of resonant double loop antennas for ATF and TFTR in order to refine the transmission line parameters. Results from the model are presented for RDL antenna designs for ATF, TFTR, Tore Supra, and for the Compact Ignition Tokamak
International Nuclear Information System (INIS)
Chesi, Stefano; Jaffe, Arthur; Loss, Daniel; Pedrocchi, Fabio L.
2013-01-01
We investigate the role that vortex loops play in characterizing eigenstates of interacting Majoranas. We give some general results and then focus on ladder Hamiltonian examples as a test of further ideas. Two methods yield exact results: (i) A mapping of certain spin Hamiltonians to quartic interactions of Majoranas shows that the spectra of these two examples coincide. (ii) In cases with reflection-symmetric Hamiltonians, we use reflection positivity for Majoranas to characterize vortices in the ground states. Two additional methods suggest wider applicability of these results: (iii) Numerical evidence suggests similar behavior for certain systems without reflection symmetry. (iv) A perturbative analysis also suggests similar behavior without the assumption of reflection symmetry
International Nuclear Information System (INIS)
Pei, L.; Klebaner, A.; Theilacker, J.; Soyars, W.; Martinez, A.; Bossert, R.; DeGraff, B.; Darve, C.
2011-01-01
The Horizontal Test Stand (HTS) SRF Cavity and Cryomodule 1 (CM1) of eight 9-cell, 1.3GHz SRF cavities are operating at Fermilab. For the cryogenic control system, how to hold liquid level constant in the cryostat by regulation of its Joule-Thompson JT-valve is very important after cryostat cool down to 2.0 K. The 72-cell cryostat liquid level response generally takes a long time delay after regulating its JT-valve; therefore, typical PID control loop should result in some cryostat parameter oscillations. This paper presents a type of PID parameter self-optimal and Time-Delay control method used to reduce cryogenic system parameters oscillation.
International Nuclear Information System (INIS)
De Witt, R.; Jepson, B.E.; Schwind, R.A.
1975-01-01
Sulfur isotopes are continuously separated and enriched using a closed loop reflux system wherein sulfur dioxide (SO 2 ) is reacted with sodium hydroxide (NaOH) or the like to form sodium hydrogen sulfite (NaHSO 3 ). Heavier sulfur isotopes are preferentially attracted to the NaHSO 3 , and subsequently reacted with sulfuric acid (H 2 SO 4 ) forming sodium hydrogen sulfate (NaHSO 4 ) and SO 2 gas, which contains increased concentrations of the heavier sulfur isotopes. This heavy isotope enriched SO 2 gas is subsequently separated and the NaHSO 4 is reacted with NaOH to form sodium sulfate (Na 2 SO 4 ), which is subsequently decomposed in an electrodialysis unit to form the NaOH and H 2 SO 4 components, which are used in the aforesaid reactions thereby effecting sulfur isotope separation and enrichment without objectionable loss of feed materials. (U.S.)
Directory of Open Access Journals (Sweden)
Rovelli Carlo
2008-07-01
Full Text Available The problem of describing the quantum behavior of gravity, and thus understanding quantum spacetime, is still open. Loop quantum gravity is a well-developed approach to this problem. It is a mathematically well-defined background-independent quantization of general relativity, with its conventional matter couplings. Today research in loop quantum gravity forms a vast area, ranging from mathematical foundations to physical applications. Among the most significant results obtained so far are: (i The computation of the spectra of geometrical quantities such as area and volume, which yield tentative quantitative predictions for Planck-scale physics. (ii A physical picture of the microstructure of quantum spacetime, characterized by Planck-scale discreteness. Discreteness emerges as a standard quantum effect from the discrete spectra, and provides a mathematical realization of Wheeler’s “spacetime foam” intuition. (iii Control of spacetime singularities, such as those in the interior of black holes and the cosmological one. This, in particular, has opened up the possibility of a theoretical investigation into the very early universe and the spacetime regions beyond the Big Bang. (iv A derivation of the Bekenstein–Hawking black-hole entropy. (v Low-energy calculations, yielding n-point functions well defined in a background-independent context. The theory is at the roots of, or strictly related to, a number of formalisms that have been developed for describing background-independent quantum field theory, such as spin foams, group field theory, causal spin networks, and others. I give here a general overview of ideas, techniques, results and open problems of this candidate theory of quantum gravity, and a guide to the relevant literature.
Rovelli, Carlo
2008-01-01
The problem of describing the quantum behavior of gravity, and thus understanding quantum spacetime , is still open. Loop quantum gravity is a well-developed approach to this problem. It is a mathematically well-defined background-independent quantization of general relativity, with its conventional matter couplings. Today research in loop quantum gravity forms a vast area, ranging from mathematical foundations to physical applications. Among the most significant results obtained so far are: (i) The computation of the spectra of geometrical quantities such as area and volume, which yield tentative quantitative predictions for Planck-scale physics. (ii) A physical picture of the microstructure of quantum spacetime, characterized by Planck-scale discreteness. Discreteness emerges as a standard quantum effect from the discrete spectra, and provides a mathematical realization of Wheeler's "spacetime foam" intuition. (iii) Control of spacetime singularities, such as those in the interior of black holes and the cosmological one. This, in particular, has opened up the possibility of a theoretical investigation into the very early universe and the spacetime regions beyond the Big Bang. (iv) A derivation of the Bekenstein-Hawking black-hole entropy. (v) Low-energy calculations, yielding n -point functions well defined in a background-independent context. The theory is at the roots of, or strictly related to, a number of formalisms that have been developed for describing background-independent quantum field theory, such as spin foams, group field theory, causal spin networks, and others. I give here a general overview of ideas, techniques, results and open problems of this candidate theory of quantum gravity, and a guide to the relevant literature.
International Nuclear Information System (INIS)
Ladd-Lively, Jennifer L
2008-01-01
The objectives of the work discussed in this report were to: (1) develop a flow loop that would simulate the purified uranium-bearing aqueous stream exiting the solvent extraction process in a natural uranium conversion plant (NUCP); (2) develop a test plan that would simulate normal operation and disturbances that could be anticipated in an NUCP; (3) use the flow loop to test commercially available flowmeters for use as safeguards monitors; and (4) recommend a flowmeter for production-scale testing at an NUCP. There has been interest in safeguarding conversion plants because the intermediate products [uranium dioxide (UO 2 ), uranium tetrafluoride (UF 4 ), and uranium hexafluoride (UF 6 )] are all suitable uranium feedstocks for producing special nuclear materials. Furthermore, if safeguards are not applied virtually any nuclear weapons program can obtain these feedstocks without detection by the International Atomic Energy Agency (IAEA). Historically, IAEA had not implemented safeguards until the purified UF 6 product was declared as feedstock for enrichment plants. H. A. Elayat et al. provide a basic definition of a safeguards system: 'The function of a safeguards system on a chemical conversion plant is in general terms to verify that no useful nuclear material is being diverted to use in a nuclear weapons program'. The IAEA now considers all highly purified uranium compounds as candidates for safeguarding. DOE is currently interested in 'developing instruments, tools, strategies, and methods that could be of use to the IAEA in the application of safeguards' for materials found in the front end of the nuclear fuel cycle-prior to the production of the uranium hexafluoride or oxides that have been the traditional starting point for IAEA safeguards. Several national laboratories, including Oak Ridge, Los Alamos, Lawrence Livermore, and Brookhaven, have been involved in developing tools or techniques for safeguarding conversion plants. This study was sponsored by
Directory of Open Access Journals (Sweden)
Stephania de Andrade Sócio
2010-06-01
Full Text Available OBJETIVO: Descrever as formas de apresentação, as alterações laboratoriais ao diagnóstico e o tratamento de crianças e adolescentes com doença de Wilson. MÉTODOS: Estudo descritivo e retrospectivo de 17 crianças e adolescentes com doença de Wilson atendidos no Ambulatório de Hepatologia Pediátrica do Hospital das Clínicas da Universidade Federal de Minas Gerais no período de 1985 a 2008. Os dados foram coletados dos prontuários e durante as consultas ambulatoriais. RESULTADOS: A idade ao diagnóstico variou de 2,8 a 15,1 anos, com média de 8,8±0,9 anos. A forma de apresentação predominante foi hepática (53%, seguida por assintomáticos provenientes de triagem familiar. O anel de Kayser-Fleischer foi encontrado em 41% dos pacientes. A ceruloplasmina encontrava-se alterada em 15/17 pacientes e o cobre urinário variou de 24 a 1000mcg/24h (mediana: 184mcg/24h. O tratamento instituído foi a D-penicilamina. Observaram-se efeitos colaterais em cinco crianças, sem necessidade de interrupção ou troca da medicação. As respostas clínica e laboratorial, com níveis normais de aminotransferases, foram evidenciadas em 14 pacientes após mediana de 10,7 meses de tratamento. Três crianças morreram (uma por hepatite fulminante e duas com complicações da insuficiência hepática grave, apesar do tratamento. CONCLUSÕES: A doença de Wilson é rara na faixa etária pediátrica. A forma de apresentação predominante é a hepática. Seu diagnóstico se baseia principalmente em dosagem de ceruloplasmina baixa, cobre livre e cobre em urina de 24 horas elevados, mas exige alto grau de suspeição. Apresenta boa resposta e tolerância ao tratamento medicamentoso.OBJECTIVE: To describe clinical symptoms, laboratory findings at diagnosis and treatment of children and adolescents with Wilson's disease. METHODS: This is a descriptive and retrospective study of a series of 17 children and adolescents with Wilson's disease, assited at the
Rahnama'i, Mohammad S; Marcelissen, Tom; Apostolidis, Apostolos; Veit-Rubin, Nikolaus; Schurch, Brigitte; Cardozo, Linda; Dmochowski, Roger
2018-01-24
This manuscript aims to address the evidence availale in the literature on the efficacy of Botulinum Toxin A (BoNT-A) and sacral neuromodulation (SNM) in patients suffering from Interstitial Cystitis (IC)/BPS and propose further research to identify mechanisms of action and establish the clinical efficacy of either therapy. At the International Consultation on Incontinence-Research Society (ICI-RS) in 2017, a panel of Functional Urologists and Urogynaecologists participated in a Think Tank (TT) discussing the management of IC/BPS by BoNT-A and SNM, using available data from both PubMed and Medicine literature searches. The role of BoNT-A and SNM in the treatment of IC/BPS are discussed and mechanisms of actions are proposed. Despite the available randomized trial data on the effect of intravesical BoNT-A treatment on symptoms of IC/BPS, a consistent conclusion of a positive effect cannot be drawn at the moment, as the published studies are small and heterogeneous in design. There is substantive evidence for the positive effects of SNM on symptoms of IC/BPS patients however, during patient selection, it is important to distinguish the degree and the location of pain in order to tailor the best therapy to the right patients. Both intravesical BoNT-A treatment and SNM have been shown to have positive effects in patients with IC/BPS. However, firm conclusions cannot yet be drawn. Patient-reported outcomes and quality of life should be assessed in addition to urinary and pain symptoms. Since current treatments mainly focus on symptomatic relief, future research should also focus on clarifying the pathogenic mechanisms involved in IC/BPS. © 2018 Wiley Periodicals, Inc.
Loop quantum cosmology: Recent progress
Indian Academy of Sciences (India)
Aspects of the full theory of loop quantum gravity can be studied in a simpler context by reducing to symmetric models like cosmological ones. This leads to several applications where loop effects play a significant role when one is sensitive to the quantum regime. As a consequence, the structure of and the approach to ...
RCD+: Fast loop modeling server.
López-Blanco, José Ramón; Canosa-Valls, Alejandro Jesús; Li, Yaohang; Chacón, Pablo
2016-07-08
Modeling loops is a critical and challenging step in protein modeling and prediction. We have developed a quick online service (http://rcd.chaconlab.org) for ab initio loop modeling combining a coarse-grained conformational search with a full-atom refinement. Our original Random Coordinate Descent (RCD) loop closure algorithm has been greatly improved to enrich the sampling distribution towards near-native conformations. These improvements include a new workflow optimization, MPI-parallelization and fast backbone angle sampling based on neighbor-dependent Ramachandran probability distributions. The server starts by efficiently searching the vast conformational space from only the loop sequence information and the environment atomic coordinates. The generated closed loop models are subsequently ranked using a fast distance-orientation dependent energy filter. Top ranked loops are refined with the Rosetta energy function to obtain accurate all-atom predictions that can be interactively inspected in an user-friendly web interface. Using standard benchmarks, the average root mean squared deviation (RMSD) is 0.8 and 1.4 Å for 8 and 12 residues loops, respectively, in the challenging modeling scenario in where the side chains of the loop environment are fully remodeled. These results are not only very competitive compared to those obtained with public state of the art methods, but also they are obtained ∼10-fold faster. © The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research.
Higher dimensional loop quantum cosmology
International Nuclear Information System (INIS)
Zhang, Xiangdong
2016-01-01
Loop quantum cosmology (LQC) is the symmetric sector of loop quantum gravity. In this paper, we generalize the structure of loop quantum cosmology to the theories with arbitrary spacetime dimensions. The isotropic and homogeneous cosmological model in n + 1 dimensions is quantized by the loop quantization method. Interestingly, we find that the underlying quantum theories are divided into two qualitatively different sectors according to spacetime dimensions. The effective Hamiltonian and modified dynamical equations of n + 1 dimensional LQC are obtained. Moreover, our results indicate that the classical big bang singularity is resolved in arbitrary spacetime dimensions by a quantum bounce. We also briefly discuss the similarities and differences between the n + 1 dimensional model and the 3 + 1 dimensional one. Our model serves as a first example of higher dimensional loop quantum cosmology and offers the possibility to investigate quantum gravity effects in higher dimensional cosmology. (orig.)
... such as kidney stones and an abnormal number of amino acids excreted in the urine. Psychological problems. These might include personality changes, depression, irritability, bipolar disorder or psychosis. Blood problems. These might include destruction ...
... water. Water that sits in copper pipes may pick up copper residue, but running water lowers the ... FAQs About NIDDK Meet the Director Offices & Divisions Staff Directory Budget & Legislative Information Advisory & Coordinating Committees Strategic ...
Symptoms may include: Abnormal posture of arms and legs Confusion or delirium Dementia Difficulty moving arms and legs, stiffness Difficulty walking (ataxia) Emotional or behavioral changes Enlargement of ...
Two-loop matching of the dipole operators for b→sγ and b→sg
International Nuclear Information System (INIS)
Greub, C.; Hurth, T.
1997-01-01
The order α s corrections to the Wilson coefficients of the dipole operators (O 7 ,O 8 ) at the matching scale μ=m W are a crucial ingredient for a complete next-to-leading logarithmic calculation of the branching ratio for b→sγ. Given the phenomenological relevance and the fact that this two-loop calculation has been done so far only by Adel and Yao, we present a detailed recalculation using a different method. Our results are in complete agreement with those of Adel and Yao. copyright 1997 The American Physical Society
International Nuclear Information System (INIS)
Fletcher, S.K.
2002-01-01
1 - Description of program or function: The three programs SPLPKG, WFCMPR, and WFAPPX provide the capability for interactively generating, comparing and approximating Wilson-Fowler Splines. The Wilson-Fowler spline is widely used in Computer Aided Design and Manufacturing (CAD/CAM) systems. It is favored for many applications because it produces a smooth, low curvature fit to planar data points. Program SPLPKG generates a Wilson-Fowler spline passing through given nodes (with given end conditions) and also generates a piecewise linear approximation to that spline within a user-defined tolerance. The program may be used to generate a 'desired' spline against which to compare other Splines generated by CAD/CAM systems. It may also be used to generate an acceptable approximation to a desired spline in the event that an acceptable spline cannot be generated by the receiving CAD/CAM system. SPLPKG writes an IGES file of points evaluated on the spline and/or a file containing the spline description. Program WFCMPR computes the maximum difference between two Wilson-Fowler Splines and may be used to verify the spline recomputed by a receiving system. It compares two Wilson-Fowler Splines with common nodes and reports the maximum distance between curves (measured perpendicular to segments) and the maximum difference of their tangents (or normals), both computed along the entire length of the Splines. Program WFAPPX computes the maximum difference between a Wilson- Fowler spline and a piecewise linear curve. It may be used to accept or reject a proposed approximation to a desired Wilson-Fowler spline, even if the origin of the approximation is unknown. The maximum deviation between these two curves, and the parameter value on the spline where it occurs are reported. 2 - Restrictions on the complexity of the problem - Maxima of: 1600 evaluation points (SPLPKG), 1000 evaluation points (WFAPPX), 1000 linear curve breakpoints (WFAPPX), 100 spline Nodes
Menger, Richard P; Storey, Christopher M; Guthikonda, Bharat; Missios, Symeon; Nanda, Anil; Cooper, John M
2015-07-01
World War I catapulted the United States from traditional isolationism to international involvement in a major European conflict. Woodrow Wilson envisaged a permanent American imprint on democracy in world affairs through participation in the League of Nations. Amid these defining events, Wilson suffered a major ischemic stroke on October 2, 1919, which left him incapacitated. What was probably his fourth and most devastating stroke was diagnosed and treated by his friend and personal physician, Admiral Cary Grayson. Grayson, who had tremendous personal and professional loyalty to Wilson, kept the severity of the stroke hidden from Congress, the American people, and even the president himself. During a cabinet briefing, Grayson formally refused to sign a document of disability and was reluctant to address the subject of presidential succession. Wilson was essentially incapacitated and hemiplegic, yet he remained an active president and all messages were relayed directly through his wife, Edith. Patient-physician confidentiality superseded national security amid the backdrop of friendship and political power on the eve of a pivotal juncture in the history of American foreign policy. It was in part because of the absence of Woodrow Wilson's vocal and unwavering support that the United States did not join the League of Nations and distanced itself from the international stage. The League of Nations would later prove powerless without American support and was unable to thwart the rise and advance of Adolf Hitler. Only after World War II did the United States assume its global leadership role and realize Wilson's visionary, yet contentious, groundwork for a Pax Americana. The authors describe Woodrow Wilson's stroke, the historical implications of his health decline, and its impact on United States foreign policy.
Fogg, Ryan; Kutikov, Alexander; Uzzo, Robert G; Canter, Daniel
2011-09-01
President Woodrow Wilson was never able to gain ratification of the Treaty of Versailles, the peace accord to end World War I. Before he could convince the American people of the importance of ratification, Wilson suffered a stroke followed by life threatening urinary sepsis due to urinary retention, and was treated by the father of modern urology, Hugh Hampton Young. The effects of these health problems are examined in the context of their implications on international affairs. Biographical sources and primary documentation of Wilson's physicians were reviewed to determine the effect of Wilson's stroke on his voiding habits. Hugh Hampton Young's evaluation and decision making is examined in depth. In the fall of 1919 President Wilson was recovering from a stroke. Shortly after the stroke his preexisting voiding dysfunction progressed to urinary retention from which urinary sepsis developed. Hugh Hampton Young advised on Wilson's case and counseled patience over surgery. The President began voiding spontaneously and recovered from sepsis. The illness left him severely weakened and unable to mount an aggressive campaign to persuade the U.S. Senate of the importance of ratifying the Treaty of Versailles. His personal physician, Admiral Cary T. Grayson, stated that the President was mentally never the same after the sepsis. Wilson's voiding dysfunction contributed to his inability to win approval for the Treaty of Versailles and the League of Nations. As a result, the United States returned to a policy of isolationism and Europe plunged into 2 decades of upheaval, leading to World War II. Copyright © 2011 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved.
Three-loop corrections to the soft anomalous dimension in multileg scattering
Almelid, Øyvind; Gardi, Einan
2016-01-01
We present the three-loop result for the soft anomalous dimension governing long-distance singularities of multi-leg gauge-theory scattering amplitudes of massless partons. We compute all contributing webs involving semi-infinite Wilson lines at three loops and obtain the complete three-loop correction to the dipole formula. We find that non-dipole corrections appear already for three coloured partons, where the correction is a constant without kinematic dependence. Kinematic dependence appears only through conformally-invariant cross ratios for four coloured partons or more, and the result can be expressed in terms of single-valued harmonic polylogarithms of weight five. While the non-dipole three-loop term does not vanish in two-particle collinear limits, its contribution to the splitting amplitude anomalous dimension reduces to a constant, and it only depends on the colour charges of the collinear pair, thereby preserving strict collinear factorization properties. Finally we verify that our result is consi...
Inhibitory rTMS applied on somatosensory cortex in Wilson's disease patients with hand dystonia.
Lozeron, Pierre; Poujois, Aurélia; Meppiel, Elodie; Masmoudi, Sana; Magnan, Thierry Peron; Vicaut, Eric; Houdart, Emmanuel; Guichard, Jean-Pierre; Trocello, Jean-Marc; Woimant, France; Kubis, Nathalie
2017-10-01
Hand dystonia is a common complication of Wilson's disease (WD), responsible for handwriting difficulties and disability. Alteration of sensorimotor integration and overactivity of the somatosensory cortex have been demonstrated in dystonia. This study investigated the immediate after effect of an inhibitory repetitive transcranial magnetic stimulation (rTMS) applied over the somatosensory cortex on the writing function in WD patients with hand dystonia. We performed a pilot prospective randomized double-blind sham-controlled crossover rTMS study. A 20-min 1-Hz rTMS session, stereotaxically guided, was applied over the left somatosensory cortex in 13 WD patients with right dystonic writer's cramp. After 3 days, each patient was crossed-over to the alternative treatment. Patients were clinically evaluated before and immediately after each rTMS session with the Unified Wilson's Disease rating scale (UWDRS), the Writers' Cramp Rating Scale (WCRS), a specifically designed scale for handwriting difficulties in Wilson's disease patients (FAR, flow, accuracy, and rhythmicity evaluation), and a visual analog scale (VAS) for handwriting discomfort. No significant change in UWDRS, WCRS, VAS, or FAR scores was observed in patients treated with somatosensory inhibitory rTMS compared to the sham protocol. The FAR negatively correlated with UWDRS (r = -0.6; P = 0.02), but not with the WCRS score, disease duration, MRI diffusion lesions, or with atrophy scores. In our experimental conditions, a single inhibitory rTMS session applied over somatosensory cortex did not improve dystonic writer cramp in WD patients.
Analytic Result for the Two-loop Six-point NMHV Amplitude in N = 4 Super Yang-Mills Theory
Energy Technology Data Exchange (ETDEWEB)
Dixon, Lance J.; /SLAC; Drummond, James M.; /CERN /Annecy, LAPTH; Henn, Johannes M.; /Humboldt U., Berlin /Princeton, Inst. Advanced Study
2012-02-15
We provide a simple analytic formula for the two-loop six-point ratio function of planar N = 4 super Yang-Mills theory. This result extends the analytic knowledge of multi-loop six-point amplitudes beyond those with maximal helicity violation. We make a natural ansatz for the symbols of the relevant functions appearing in the two-loop amplitude, and impose various consistency conditions, including symmetry, the absence of spurious poles, the correct collinear behavior, and agreement with the operator product expansion for light-like (super) Wilson loops. This information reduces the ansatz to a small number of relatively simple functions. In order to fix these parameters uniquely, we utilize an explicit representation of the amplitude in terms of loop integrals that can be evaluated analytically in various kinematic limits. The final compact analytic result is expressed in terms of classical polylogarithms, whose arguments are rational functions of the dual conformal cross-ratios, plus precisely two functions that are not of this type. One of the functions, the loop integral {Omega}{sup (2)}, also plays a key role in a new representation of the remainder function R{sub 6}{sup (2)} in the maximally helicity violating sector. Another interesting feature at two loops is the appearance of a new (parity odd) x (parity odd) sector of the amplitude, which is absent at one loop, and which is uniquely determined in a natural way in terms of the more familiar (parity even) x (parity even) part. The second non-polylogarithmic function, the loop integral {tilde {Omega}}{sup (2)}, characterizes this sector. Both {Omega}{sup (2)} and {tilde {Omega}}{sup (2)} can be expressed as one-dimensional integrals over classical polylogarithms with rational arguments.
Closed-form irreducible differential formulations of the Wilson renormalization group
International Nuclear Information System (INIS)
Vvedensky, D.D.; Chang, T.S.; Nicoll, J.F.
1983-01-01
We present a detailed derivation of the one-particle--irreducible (1PI) differential renormalization-group generators originally developed by Nicoll and Chang and by Chang, Nicoll, and Young. We illustrate the machinery of the irreducible formulation by calculating to order epsilon 2 the characteristic time exponent z for the time-dependent Ginsburg-Landau model in the cases of conserved and nonconserved order parameter. We then calculate both z and eta to order epsilon 2 by applying to the 1PI generator an extension of the operator expansion technique developed by Wegner for the Wilson smooth-cutoff renormalization-group generator
Directory of Open Access Journals (Sweden)
Matthew Wells
2016-06-01
Full Text Available The purpose of this paper is to explore the type, form, and methodology of history written by practicing architects following the arrival of kunstgeschichte in Britain. Through an analysis of historical writings by Alison and Peter Smithson, and Colin St John Wilson a series of topics are explored including the relationship between history and practice, the use of different narrative structures, and the qualities that a practicing architect can bring to the study of the past. The paper concludes by emphasising that whilst all history is contemporary history, the association between history and its architect-author was not simplistic but a complex interrelationship of position and intention.
1982-08-27
FREQUENCY FOR SIX-HOUR STORM FROM TP-40 AND El 1110-2-1411 WILSON BRANCH, CHERAW, SOUTH CAROLINA *• RETURN ADJUSTED, FREQUENCY RAINFALL- -__ _(INCHES) 10-YR...TOTAL DAMAGE 308.46 321.51 371. El 375.85 BENEFITS 24. The material presented herein provides the basis for establishing the economic benefits associated...tish , rept i le’ and amphibians. In fact, accord iw, to Brinson e t al (196), ri par ian ecosvst ems s,,pport a greatevr diversity oI wild! tifo than
Eduardo Solá Franco, Wilson Paccha, Transtango: estrategias de las masculinidades en Ecuador
Vega Suriaga, Edgar
2014-01-01
La presente tesis doctoral titulada "Eduardo Solá Franco, Wilson Paccha, Transtango: estrategias de las masculinidades en Ecuador" plantea las dificultades, posibilidades y límites de la representación de las masculinidades en las artes plásticas y en el arte contemporáneo en Ecuador. Para ello, en un primer capítulo se propone un análisis de las masculinidades contemporáneas como resultado de la emergencia del sujeto masculino moderno decimonónico. En ese análisis, se plantea que en el siglo...
Nucleon form factors and couplings with N_{f}=2+1 Wilson fermions
Djukanovic, D.; Harris, T.; von Hippel, G.; Junnarkar, P.; Meyer, H. B.; Wittig, H.
We present updated results on the nucleon electromagnetic form factors and axial coupling calculated using CLS ensembles with $N_\\mathrm{f}=2+1$ dynamical flavours of Wilson fermions. The measurements are performed on large, fine lattices with a pseudoscalar mass reaching down to 200 MeV. The truncated-solver method is employed to reduce the variance of the measurements. Estimation of the matrix elements is challenging due to large contamination from excited states and further investigation is necessary to bring these effects under control.
Low-lying eigenmodes of the Wilson-Dirac operator and correlations with topological objects
International Nuclear Information System (INIS)
Kusterer, Daniel-Jens; Hedditch, John; Kamleh, Waseem; Leinweber, D.B.; Williams, Anthony G.
2002-01-01
The probability density of low-lying eigenvectors of the hermitian Wilson-Dirac operator H(κ)=γ 5 D W (κ) is examined. Comparisons in position and size between eigenvectors, topological charge and action density are made. We do this for standard Monte-Carlo generated SU(3) background fields and for single instanton background fields. Both hot and cooled SU(3) background fields are considered. An instanton model is fitted to eigenmodes and topological charge density and the sizes and positions of these are compared
Finite-temperature phase structure of lattice QCD with Wilson quark action
International Nuclear Information System (INIS)
Aoki, S.; Ukawa, A.; Umemura, T.
1996-01-01
The long-standing issue of the nature of the critical line of lattice QCD with the Wilson quark action at finite temperatures, defined to be the line of vanishing pion screening mass, and its relation to the line of finite-temperature chiral transition is examined. Presented are both analytical and numerical evidence that the critical line forms a cusp at a finite gauge coupling, and that the line of chiral transition runs past the tip of the cusp without touching the critical line. Implications on the continuum limit and the flavor dependence of chiral transition are discussed. copyright 1996 The American Physical Society
Hallazgo del Falarópodo de Wilson (Steganopus Tricolor en Colombia
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Dugand Armando
1947-06-01
Full Text Available La familia de las Falaropódidas (Charadriiformes.-Sub-Orden Charadrii no ha sido señalada todavía en Colombia. Por lo tanto es interesante registrar aquí por primera vez su presencia ocasional en este país con un ejemplar del Falarópodo de Wilson coleccionado cerca de Popayán, que ha llegado a nuestro Instituto como parte de un canje de pieles con el Museo de Historia Natural de la Universidad del Cauca.
Phenotype and genotype of 87 patients with Mowat-Wilson syndrome and recommendations for care
DEFF Research Database (Denmark)
Ivanovski, Ivan; Djuric, Olivera; Caraffi, Stefano Giuseppe
2018-01-01
PurposeMowat-Wilson syndrome (MWS) is a rare intellectual disability/multiple congenital anomalies syndrome caused by heterozygous mutation of the ZEB2 gene. It is generally underestimated because its rarity and phenotypic variability sometimes make it difficult to recognize. Here, we aimed...... to better delineate the phenotype, natural history, and genotype-phenotype correlations of MWS.MethodsIn a collaborative study, we analyzed clinical data for 87 patients with molecularly confirmed diagnosis. We described the prevalence of all clinical aspects, including attainment of neurodevelopmental...
DEFF Research Database (Denmark)
Korman, J.D.; Volenberg, I.; Balko, J.
2008-01-01
Acute liver failure (ALF) due to Wilson disease (WD) is invariably fatal without emergency liver transplantation. Therefore, rapid diagnosis of WD should aid prompt transplant listing. To identify the best method for diagnosis of ALF due to WD (ALF-WD), data and serum were collected from 140 ALF...... patients (16 with WD), 29 with other chronic liver diseases and 17 with treated chronic WD. Ceruloplasmin (Cp) was measured by both oxidase activity and nephelometry and serum copper levels by atomic absorption spectroscopy. In patients with ALF, a serum Cp
BMN correlators by loop equations
International Nuclear Information System (INIS)
Eynard, Bertrand; Kristjansen, Charlotte
2002-01-01
In the BMN approach to N=4 SYM a large class of correlators of interest are expressible in terms of expectation values of traces of words in a zero-dimensional gaussian complex matrix model. We develop a loop-equation based, analytic strategy for evaluating such expectation values to any order in the genus expansion. We reproduce the expectation values which were needed for the calculation of the one-loop, genus one correction to the anomalous dimension of BMN-operators and which were earlier obtained by combinatorial means. Furthermore, we present the expectation values needed for the calculation of the one-loop, genus two correction. (author)
Directory of Open Access Journals (Sweden)
Vaishali Chandrashekhar
2015-06-01
Full Text Available BACKGROUND : This study was carried out to evaluate usefulness of preoperative Mallampati & Wilson’s score grading as a predictor for difficult laryngoscopy & intubation . AIMS : To determine the accuracy of the modified Mallampati test and Wilson score for predicting difficult tracheal intubation and correlation with Cormack Lehane grading . METHODS : This prospective randomized cross sectional Study carried out in 200 patients , posted for surgical procedure under GA with ETT intubation. Preoperative airway assessment using Mallampati grading (MPG & Wilson score done. Conventional anesthesia t echnique followed. Cormack Lehane grading done at laryngoscopy & correlated with previous scores for each patient. RESULTS : A MPG of I/II was found in 140 patients (70% , while 60 patients (30% were class III/IV. 138 patients (69% had a Wilson score of 0 /1 , while 60(30% had a score of 2/3 and 2 patients (1% scored ≥4. One hundred & eighty patients (90% were classified as Cormack - Lehane grade I/II , while 20 patients (10% were considered grade III/IV. Of the 60 patients with a Wilson score of 2/3 , 6 cas es (10% two attempts were required and in 2 cases (3.3% in spite of more than two attempts intubation proved impossible with the conventional laryngoscope , articulated McCoy blade was used. Two patients with a Wilson score ≥4 were intubated with gum elas tic bougie , using articulated McCoy blade. Overall , out of 200 , in 6 patients (3% two attempts of intubation was required and 4 patients (2% intubation required the use of some kind of gadget other than conventional laryngoscope and more than 2 attempts. The correlation between the Cormack - Lehane classification and the number of endotracheal intubation attempts showed that of the 180 patients with I / II grade , 4 patients (1.3% two attempts were required. Of the 20 patients classified as Cormack - Lehane III/IV , 4 cases (20% intubation proved impossible with conventional technique. This
International Nuclear Information System (INIS)
Kalibjian, R.; Chong, Y.P.; Prono, D.S.; Cavagnolo, H.R.
1984-06-01
The ATA provides an electron beam pulse of 70-ns duration at a 1-Hz rate. Our present optical diagnostics technique involve the imaging of the visible light generated by the beam incident onto the plant of a thin sheet of material. It has already been demonstrated that the light generated has a sufficiently fast temporal reponse in performing beam diagnostics. Notwithstanding possible beam emittance degradation due to scattering in the thin sheet, the observation of beam spatial profiles with relatively high efficiencies has provided data complementary to that obtained from beam wall current monitors and from various x-ray probes and other electrical probes. The optical image sensor consists of a gated, intensified television system. The gate pulse of the image intensifier can be appropriately delayed to give frames that are time-positioned from the head to the tail of the beam with a minimum gate time of 5-ns. The spatial correlation of the time frames from pulse to pulse is very good for a stable electron beam; however, when instabilities do occur, it is difficult to properly assess the spatial composition of the head and the tail of the beam on a pulse-to-pulse basis. Multiple gating within a pulse duration becomes desirable but cannot be performed because the recycle time (20-ms) of the TV system is much longer than the beam pulse. For this reason we have developed an optical-loop framing technique that will allow the recording of two frames within one pulse duration with our present gated/intensified TV system
Loop quantum cosmology: Recent progress
Indian Academy of Sciences (India)
. These techniques and their implications can be illustrated and tested in simple sit- uations by introducing symmetries, which is the origin of loop quantum cosmology. The symmetry reduction can be done in such a way that the characteristic ...
Daily survival rate and habitat characteristics of nests of Wilson's Plover
Zinsser, Elizabeth; Sanders, Felicia J.; Gerard, Patrick D.; Jodice, Patrick G.R.
2017-01-01
We assessed habitat characteristics and measured daily survival rate of 72 nests of Charadrius wilsonia (Wilson's Plover) during 2012 and 2013 on South Island and Sand Island on the central coast of South Carolina. At both study areas, nest sites were located at slightly higher elevations (i.e., small platforms of sand) relative to randomly selected nearby unused sites, and nests at each study area also appeared to be situated to enhance crypsis and/or vigilance. Daily survival rate (DSR) of nests ranged from 0.969 to 0.988 among study sites and years, and the probability of nest survival ranged from 0.405 to 0.764. Flooding and predation were the most common causes of nest failure at both sites. At South Island, DSR was most strongly related to maximum tide height, which suggests that flooding and overwash may be common causes of nest loss for Wilson's Plovers at these study sites. The difference in model results between the 2 nearby study sites may be partially due to more-frequent flooding at Sand Island because of some underlying yet unmeasured physiographic feature. Remaining data gaps for the species include regional assessments of nest and chick survival and habitat requirements during chick rearing.
Towards true unipolar ECG recording without the Wilson central terminal (preliminary results)
International Nuclear Information System (INIS)
Gargiulo, G D; McEwan, A L; Jin, C; Thiagalingam, A; Bifulco, P; Cesarelli, M; Tapson, J; Van Schaik, A
2013-01-01
We present an innovative bio-potential front-end capable of recording true unipolar ECG leads for the first time without making use of the Wilson central terminal. In addition to the convenience in applications such as continuous monitoring and rapid diagnosis, the information in unipolar recordings may yield unique diagnostic information as it avoids the need to essentially subtract data or make use of the averaging effect imposed from the Wilson central terminal. The system also allows direct, real-time software calculation of signals corresponding to standard ECG leads which achieve correlations in excess of 92% with a gold standard ECG during a parallel in vivo recording. In addition, the implemented circuit is wideband (0.05–1000 Hz), compatible with standard (Ag/AgCl) bio-potential electrodes, and dry (paste-less) textile electrodes. The circuit is also low power, requiring less than 50 mW (when powered at 12 V) per standard ECG lead (two channels required). It is therefore well suited for wearable, long-term applications. (paper)
Theological presuppositions of the evolutionary epic: From Robert Chambers to E. O. Wilson.
Megill, Allan
2016-08-01
We can trace the "evolutionary epic" (named by E. O. Wilson, 1978) back to earlier writers, beginning with Robert Chambers (1844). Its basic elements are: fixation on seeing human history as rooted in biology; an aspiration toward telling the whole history of humankind (in its essential features); and insistence on the overall coherence of the projected narrative. The claim to coherence depends on assuming either that the universe possesses an "embedded rationality," or that it is guided by divine purpose. This article proposes the term "idealism" to refer to these two assumptions taken together, for in practice they were closely linked. Nietzsche (1881) was perhaps the first thinker to point out the evolutionary epic's dependence on such an idealism, and he also pointed out that the assumptions of embedded rationality and of divine purpose are closely connected. Darwin's theory of descent with modification (1859) was sharply inconsistent with these assumptions: he was not an "idealist" in the sense indicated here, and not a proponent of the evolutionary epic. Proclaiming his "materialism," Wilson (1978) failed to acknowledge that the epic depends on idealist assumptions; other adherents of the genre (M. Dowd, L. Rue) resurrect (knowingly or not) its theological roots. Copyright © 2015 Elsevier Ltd. All rights reserved.
Islands as model systems in ecology and evolution: prospects fifty years after MacArthur-Wilson.
Warren, Ben H; Simberloff, Daniel; Ricklefs, Robert E; Aguilée, Robin; Condamine, Fabien L; Gravel, Dominique; Morlon, Hélène; Mouquet, Nicolas; Rosindell, James; Casquet, Juliane; Conti, Elena; Cornuault, Josselin; Fernández-Palacios, José María; Hengl, Tomislav; Norder, Sietze J; Rijsdijk, Kenneth F; Sanmartín, Isabel; Strasberg, Dominique; Triantis, Kostas A; Valente, Luis M; Whittaker, Robert J; Gillespie, Rosemary G; Emerson, Brent C; Thébaud, Christophe
2015-02-01
The study of islands as model systems has played an important role in the development of evolutionary and ecological theory. The 50th anniversary of MacArthur and Wilson's (December 1963) article, 'An equilibrium theory of insular zoogeography', was a recent milestone for this theme. Since 1963, island systems have provided new insights into the formation of ecological communities. Here, building on such developments, we highlight prospects for research on islands to improve our understanding of the ecology and evolution of communities in general. Throughout, we emphasise how attributes of islands combine to provide unusual research opportunities, the implications of which stretch far beyond islands. Molecular tools and increasing data acquisition now permit re-assessment of some fundamental issues that interested MacArthur and Wilson. These include the formation of ecological networks, species abundance distributions, and the contribution of evolution to community assembly. We also extend our prospects to other fields of ecology and evolution - understanding ecosystem functioning, speciation and diversification - frequently employing assets of oceanic islands in inferring the geographic area within which evolution has occurred, and potential barriers to gene flow. Although island-based theory is continually being enriched, incorporating non-equilibrium dynamics is identified as a major challenge for the future. © 2014 John Wiley & Sons Ltd/CNRS.
Chromosomenindividualität or Entmischung? The debate between Paolo Della Valle and Edmund B. Wilson.
Volpone, Alessandro
2015-01-01
At the beginning of the twentieth century, the Italian cytologist Paolo Della Valle developed a theory of instable chromosomes (teoria dei cromosomi labili). He radically criticized the so-called Sutton-Boveri hypothesis (Martins and Martins, Genetics and Molecular Biology, 22:261-271, 1999), focusing on numerical constancy in the species and individuality. On the basis of bibliographical review and personal observations, he maintained that the chromosomes were neither stable bodies, nor permanent structures, but transitory cellular materials, resulting from the periodical rearrangement of the chromatin during the cell division. German and English-speaking biologists reacted. The paper shows some content of the argumentations used by Thomas H. Montgomery and especially Edmund B. Wilson. The discussion was characterized by the same data which is interpretedby different scholars in different ways. And the point is that no one of them had the decisive test to demonstrate his own point of view. Wilson simply invoked on his behalf a certain 'common sense', defending at least a 'high degree of constancy'. The debate waned along with the reception of Morgan's chromosome theory of heredity, but only the advent of molecular biology definitively stated the nature of chromosomes as permanent structures of the cell.
Characterization of toxic conditions above Wilson's Creek National Battlefield Park, Missouri
Pulley, T.S.; Nimmo, D.W.R.; Tessari, J.D.
1998-01-01
Wilson's Creek has an extensive history of toxicity from both point and nonpoint sources. Seven-day chronic daphnid (Ceriodaphnia dubia) bioassays identified one toxic site in the Wilson's Creek watershed. Procedures for the characterization phase of a Toxicity Identification Evaluation (TIE) were modified for chronic assessment and performed on four water samples from the toxic site. The characterization involved chemical/physical alterations of samples, combined with bioassays, to help in identification of the class(es) of toxicants; followed by chemical analyses. To help understand the additivity of mixtures, toxic units were derived. Successive samples contained concentrations of copper, cadmium, nickel and zinc that literature values describe as being chronically toxic to daphnids. Summed chronic toxic units for these values greatly exceeded ambient toxic units, and more than accounted for observed toxicity. Substantial fluctuations in water quality occurred over the five sampling periods of the characterization studies and a Test of Methods, June through August, 1991. This variability illustrates the difficulty in detecting and documenting nonpoint sources of pollution. Tests using living organisms, in conjunction with toxicity identification methods, on samples taken over time appear to be appropriate for detecting acute and chronic toxicity in areas impacted by intermittent point and nonpoint-source toxicity.
[Ecchymosis as the presenting manifestation of Wilson disease: A case report].
Bayer, G; Bauvois, A; Mankikian, J; Tardieu, M; Maillot, F; Salame, E; Woimant, F; Poujois, A; Viana, M; Legras, A
2017-06-01
The presence of a psychiatric disorder during the course of an organic disease is a common cause of delayed diagnosis. We report a 16-year-old girl who was admitted with thrombocytopenia and had a two-year history of neuropsychiatric disorder which was attributed to a difficult family situation. Neurological examination showed a frontal lobe disorder and extrapyramidal manifestations. The thrombocytopenia was attributed to liver cirrhosis. These neurological and hepatic injuries were consistent with a metabolic disease, most likely Wilson disease. This was supported by the presence of a corneal Kayser-Fleischer ring and a decreased ceruloplasmin concentration. An urgent liver transplantation was required due to worsening neurological symptoms. Wilson disease is a rare genetic disease caused by copper toxicity. It is characterized by combined hepatic and neurologic damage to varying degrees and can develop at any age. Urgent treatment is required, but the diagnosis may be delayed by prevailing psychiatric symptoms. Copyright © 2016 Société Nationale Française de Médecine Interne (SNFMI). Published by Elsevier SAS. All rights reserved.
Construction of the international system of Versailles, according to the doctrine of Woodrow Wilson
Directory of Open Access Journals (Sweden)
MSc. Albulena Halili
2011-12-01
Full Text Available Mapping of the international system after the First World War took place in the Conference of Versailles, where a peace treaty was negotiated to end this war, and would reshape the world order. The key role in negotiating peace was handed to the United States of America, and its President Woodrow Wilson. This paper aims to elaborate the doctrine of US President Wilson, presented through the Fourteen Points, which were the basis for the international system that was created after First World War. Two of Wilson’s Fourteen Points, which are the object of study in this paper, had the most important impact on international relations, thereby transforming into international law principles, respected to this day: the right of the people for self-determination, which led to the destruction of multi-national empires, and the creation of a association of nations, which resulted in the establishment of the League of Nations, a predecessor of United Nations. The methodological approach used in this paper is analytical-theoretical, and is based on contemporary literature. It aims to identify the strong and weak sides of this doctrine, and its influence in the establishment of the Versailles international system, which only lasted twenty years. Conclusions from this paper are that the Fourteen Points not only served for the mapping of the Versailles international system but also for the establishment of preceding international systems. Many of those principles are the foundation of contemporary international relations
Dynamical behaviour in coronal loops
Haisch, Bernhard M.
1986-01-01
Rapid variability has been found in two active region coronal loops observed by the X-ray Polychromator (XRP) and the Hard X-ray Imaging Spectrometer (HXIS) onboard the Solar Maximum Mission (SMM). There appear to be surprisingly few observations of the short-time scale behavior of hot loops, and the evidence presented herein lends support to the hypothesis that coronal heating may be impulsive and driven by flaring.
Closed Loop Fluid Delivery System
2014-02-28
loop fluid delivery system (CLFDS) will integrate a vital signs monitor ( VSM ) and high speed infusion pump (Pump) to respond quickly to drops in...Interface (GUI) shows VSM data, allows the user to select from several injury types (head, uncontrolled hemorrhage, controlled hemorrhage, and three total...the bedrock for future Closed Loop Fluid System Pre-Market Approval application(s) to FDA. 6. Major Issues Clinical study testing revealed a
Energy Technology Data Exchange (ETDEWEB)
Walter, M.G.A.
2004-02-01
We consider several examples of a special class of heterotic compactifications, i.e. heterotic E{sub 8} x E{sub 8} orbifolds with Wilson line backgrounds. By developing a local perspective we show that a brane world like picture emerges. As an important result we prove that the local massless spectrum at such a brane can always be traced back to the global spectrum of a (different) orbifold without Wilson lines. One particular implication of this result is that the use of (discrete) Wilson lines for the construction of phenomenologically interesting models has to be rethought. We show that stringy constraints render the brane spectra consistent. Using our local picture we are able to compute the local anomalies appearing at the different branes for our examples and show that they can all be cancelled by a local version of the Green-Schwarz mechanism at the same time. (orig.)
Hildon, Zoe J-L; Tan, Chuen Seng; Shiraz, Farah; Ng, Wai Chong; Deng, Xiaodong; Koh, Gerald Choon Huat; Tan, Kelvin Bryan; Philp, Ian; Wiggins, Dick; Aw, Su; Wu, Treena; Vrijhoef, Hubertus J M
2018-02-17
This study introduces the conceptual basis and operational measure, of BioPyschoSocial (BPS) health and related risk to better understand how well older people are managing and to screen for risk status. The BPS Risk Screener is constructed to detect vulnerability at older ages, and seeks to measure dynamic processes that place equal emphasis on Psycho-emotional and Socio-interpersonal risks, as Bio-functional ones. We validate the proposed measure and describe its application to programming. We undertook a quantitative cross-sectional, psychometric study with n = 1325 older Singaporeans, aged 60 and over. We adapted the EASYCare 2010 and Lubben Social Network Scale questionnaires to help determine the BPS domains using factor analysis from which we derive the BPS Risk Screener items. We then confirm its structure, and test the scoring system. The score is initially validated against self-reported general health then modelled against: number of falls; cognitive impairment; longstanding diseases; and further tested against service utilization (linked administrative data). Three B, P and S clusters are defined and identified and a BPS managing score ('doing' well, or 'some', 'many', and 'overwhelming problems') calculated such that the risk of problematic additive BPS effects, what we term health 'loads', are accounted for. Thirty-five items (factor loadings over 0.5) clustered into three distinct B, P, S domains and were found to be independently associated with self-reported health: B: 1.99 (1.64 to 2.41), P: 1.59 (1.28 to 1.98), S: 1.33 (1.10 to 1.60). The fit improved when combined into the managing score 2.33 (1.92 to 2.83, change sensitive.
One-loop effect of null-like cosmology's holographic dual super-Yang-Mills
International Nuclear Information System (INIS)
Lin, F.-L.; Tomino, Dan
2007-01-01
We calculate the 1-loop effect in super-Yang-Mills which preserves 1/4-supersymmetries and is holographically dual to the null-like cosmology with a big-bang singularity. Though the bosonic and fermionic spectra do not agree precisely, we do obtain vanishing 1-loop vacuum energy for generic warped plane-wave type backgrounds with a big-bang singularity. Moreover, we find that the cosmological 'constant' contributed either by bosons or fermions is time-dependent. The issues about the particle production of some background and about the UV structure are also commented. We argue that the effective higher derivative interactions are suppressed as long as the Fourier transform of the time-dependent coupling is UV-finite. Our result holds for scalar configurations that are BPS but with arbitrary time-dependence. This suggests the existence of non-renormalization theorem for such a new class of time-dependent theories. Altogether, it implies that such a super-Yang-Mills is scale-invariant, and that its dual bulk quantum gravity might behave regularly near the big bang
S-duality, 't Hooft operators and the operator product expansion
Gomis, Jaume; Okuda, Takuya
2009-09-01
We study S-duality in Script N = 4 super Yang-Mills with an arbitrary gauge group by determining the operator product expansion of the circular BPS Wilson and 't Hooft loop operators. The coefficients in the expansion of an 't Hooft loop operator for chiral primary operators and the stress-energy tensor are calculated in perturbation theory using the quantum path-integral definition of the 't Hooft operator recently proposed. The corresponding operator product coefficients for the dual Wilson loop operator are determined in the strong coupling expansion. The results for the 't Hooft operator in the weak coupling expansion exactly reproduce those for the dual Wilson loop operator in the strong coupling expansion, thereby demonstrating the quantitative prediction of S-duality for these observables.
Flux formulation of loop quantum gravity: classical framework
Dittrich, Bianca; Geiller, Marc
2015-07-01
We recently introduced a new representation for loop quantum gravity (LQG), which is based on the BF vacuum and is in this sense much nearer to the spirit of spin foam dynamics. In the present paper we lay out the classical framework underlying this new formulation. The central objects in our construction are the so-called integrated fluxes, which are defined as the integral of the electric field variable over surfaces of codimension one, and related in turn to Wilson surface operators. These integrated flux observables will play an important role in the coarse graining of states in LQG, and can be used to encode in this context the notion of curvature-induced torsion. We furthermore define a continuum phase space as the modified projective limit of a family of discrete phase spaces based on triangulations. This continuum phase space yields a continuum (holonomy-flux) algebra of observables. We show that the corresponding Poisson algebra is closed by computing the Poisson brackets between the integrated fluxes, which have the novel property of being allowed to intersect each other.
Douzas, George; Grammatikopoulos, Theodoros; Zoupanos, George
2009-02-01
We consider a mathcal{N}=1 supersymmetric E 8 gauge theory, defined in ten dimensions and we determine all four-dimensional gauge theories resulting from the generalized dimensional reduction à la Forgacs-Manton over coset spaces, followed by a subsequent application of the Wilson flux spontaneous symmetry-breaking mechanism. Our investigation is constrained only by the requirements that (i) the dimensional reduction leads to the potentially phenomenologically interesting, anomaly-free, four-dimensional E 6, SO10 and SU5 GUTs and (ii) the Wilson flux mechanism makes use only of the freely acting discrete symmetries of all possible six-dimensional coset spaces.
Analytic result for the two-loop six-point NMHV amplitude in N=4 super Yang-Mills theory
Dixon, Lance J.; Henn, Johannes M.
2012-01-01
We provide a simple analytic formula for the two-loop six-point ratio function of planar N = 4 super Yang-Mills theory. This result extends the analytic knowledge of multi-loop six-point amplitudes beyond those with maximal helicity violation. We make a natural ansatz for the symbols of the relevant functions appearing in the two-loop amplitude, and impose various consistency conditions, including symmetry, the absence of spurious poles, the correct collinear behaviour, and agreement with the operator product expansion for light-like (super) Wilson loops. This information reduces the ansatz to a small number of relatively simple functions. In order to fix these parameters uniquely, we utilize an explicit representation of the amplitude in terms of loop integrals that can be evaluated analytically in various kinematic limits. The final compact analytic result is expressed in terms of classical polylogarithms, whose arguments are rational functions of the dual conformal cross-ratios, plus precisely two function...
Temperature measurement of accelerator cell solenoid loop
International Nuclear Information System (INIS)
Mu Fan; Dong Pan; Dai Zhiyong
2010-01-01
This paper presents the research on temperature measurement of solenoid loop. The measuring temperature fiber is layered in solenoid loop for the accelerator cell. When the solenoid loop is supplied with high current form a constant current source, its temperature increases rapidly. The temperature fiber can measure the temperature of the solenoid loop and get temperature measurement rule. Experiment and simulation show temperature of interior solenoid loop the highest and it decreases from the interior to the exterior of solenoid loop. To control temperature of solenoid loop under 60 degree C, simulation displays load interval of constant current source with 80 A current should be at least is 17.5 minutes. (authors)
Tritium Management Loop Design Status
Energy Technology Data Exchange (ETDEWEB)
Rader, Jordan D. [ORNL; Felde, David K. [ORNL; McFarlane, Joanna [ORNL; Greenwood, Michael Scott [ORNL; Qualls, A L. [ORNL; Calderoni, Pattrick [Idaho National Laboratory (INL)
2017-12-01
This report summarizes physical, chemical, and engineering analyses that have been done to support the development of a test loop to study tritium migration in 2LiF-BeF2 salts. The loop will operate under turbulent flow and a schematic of the apparatus has been used to develop a model in Mathcad to suggest flow parameters that should be targeted in loop operation. The introduction of tritium into the loop has been discussed as well as various means to capture or divert the tritium from egress through a test assembly. Permeation was calculated starting with a Modelica model for a transport through a nickel window into a vacuum, and modifying it for a FLiBe system with an argon sweep gas on the downstream side of the permeation interface. Results suggest that tritium removal with a simple tubular permeation device will occur readily. Although this system is idealized, it suggests that rapid measurement capability in the loop may be necessary to study and understand tritium removal from the system.
Schäfer, M; Weiss, K H; Merle, U; Stremmel, W; Rasp, B
2010-10-01
The importance of disease-related topics can vary widely between patients and doctors. Patient organisations such as the German Verein Morbus Wilson e. V. can overcome this discrepancy. The goal of the present cooperative study was the collection of topics important to Wilson patients by asking patients to generate paintings about their disease. Patients with Wilson disease were asked by mail to draw paintings about their disease and to donate them to the Verein Morbus Wilson e. V. 32 paintings from 27 patients were donated. The majority of the patients added written comments to their art work. Disease-related topics included in the paintings were as follows: psychological work-up of the disease 33 % (n = 11), presentation of affected organs (liver/brain) 22 % (n = 6), therapy 19 % (n = 5), diagnostic path 15 % (n = 4), inheritance 15 % (n = 4), copper-related diet 11 % (n = 3). 33 % (n = 11) of the paintings were composed of two parts reflecting before and after the disease or presenting the individual time course of the disease. Psychological aspects of disease acceptance are the prominent topic in the paintings. The timepoint of diagnosis is experienced as major change in life. The paintings enable both the patient organisation and the caretakers to put more focus on the psychological aspects of the disease. Asking for paintings opens a new channel for patient-physician contacts and produces a feeling of interest and competence in patients. © Georg Thieme Verlag KG Stuttgart · New York.
Exact half-BPS flux solutions in M theory with D(2,1;c';0)2 symmetry: Local solutions
Estes, John; Feldman, Roman; Krym, Darya
2013-02-01
We construct the most general local solutions to 11-dimensional supergravity (or M theory), which are invariant under the superalgebra D(2,1;c';0)⊕D(2,1;c';0) for all values of the parameter c'. The BPS constraints are reduced to a single linear partial differential equation on a complex function G. The physical fields of the solutions are determined by c', a freely chosen harmonic function h, and the complex function G. h and G are both functions on a two-dimensional compact Riemannian manifold. We obtain the expressions for the metric and the field strength in terms of G, h, and c' and show that these are indeed valid solutions of the Einstein, Maxwell, and Bianchi equations. Finally we give a construction of one parameter deformations of AdS7×S4 and AdS4×S7 as a function of c'.
Kotfis, Katarzyna; Zegan-Barańska, Małgorzata; Szydłowski, Łukasz; Żukowski, Maciej; Ely, Wes E
2017-01-01
Many patients treated in the intensive care unit (ICU) experience pain that is a source of suffering and leaves a longterm imprint (chronic pain, post-traumatic stress disorder). Nearly 30% of patients experience pain at rest, while the percentage increases to 50% during nursing procedures. Pain in ICU patients can be divided into four categories: continuous ICU treatment-related pain/discomfort, acute illness-related pain, intermittent procedural pain and pre-existing chronic pain present before ICU admission. As daily nursing procedures and interventions performed in the ICU may be a potential source of pain, it is crucial to use simple pain monitoring tools. The assessment of pain intensity in ICU patients remains an everyday challenge for clinicians, especially in sedated, intubated and mechanically ventilated patients. Regular assessment of pain intensity leads to improved outcome and better quality of life of patients in the ICU and after discharge from ICU. The gold standard in pain evaluation is patient self-reporting, which is not always possible. Current research shows that the two tools best validated for patients unable to self-report pain are the Behavioral Pain Scale (BPS) and the Critical Care Pain Observation Tool (CPOT). Although international guidelines recommend the use of validated tools for pain evaluation, they underline the need for translation into a given language. The authors of this publication obtained an official agreement from the authors of the two behavioral scales - CPOT and BPS - for translation into Polish. Validation of these tools in the Polish population will aid their wider use in pain assessment in ICUs in Poland.
Fixed Points of Wegner-Wilson Flows and Many-Body Localization
Pekker, David; Clark, Bryan K.; Oganesyan, Vadim; Refael, Gil
2017-08-01
Many-body localization (MBL) is a phase of matter that is characterized by the absence of thermalization. Dynamical generation of a large number of local quantum numbers has been identified as one key characteristic of this phase, quite possibly the microscopic mechanism of breakdown of thermalization and the phase transition itself. We formulate a robust algorithm, based on Wegner-Wilson flow (WWF) renormalization, for computing these conserved quantities and their interactions. We present evidence for the existence of distinct fixed point distributions of the latter: a Gaussian white-noise-like distribution in the ergodic phase, a 1 /f law inside the MBL phase, and scale-free distributions in the transition regime.
The hermitian Wilson-Dirac operator in smooth SU(2) instanton backgrounds
International Nuclear Information System (INIS)
Edwards, R.G.; Heller, U.M.; Narayanan, R.
1998-01-01
We study the spectral flow of the hermitian Wilson-Dirac operator H(m) as a function of m in smooth SU(2) instanton backgrounds on the lattice. For a single instanton background with Dirichlet boundary conditions on H(m), we find a level crossing in the spectral flow of H(m), and we find the shape of the crossing mode at the crossing point to be in good agreement with the zero-mode associated with the single instanton background. With anti-periodic boundary conditions on H(m), we find that the instanton background in the singular gauge has the correct spectral flow but the one in regular gauge does not. We also investigate the spectral flows of two instanton and instanton-anti-instanton backgrounds. (orig.)
International Nuclear Information System (INIS)
Kuwert, T.; Scholz, D.; Milz, M.; Herzog, H.; Feinendegen, L.E.; Hefter, H.; Weiss, P.; Arendt, G.; Loken, M.; Minnesota Univ., Minneapolis, MN; Hennerici, M.
1992-01-01
Using positron emission tomography (PET), the regional cerebral metabolic rate of glucose consumption (rCMRGlc) was measured in 14 patients with Wilson's disease (WD) and 23 normal subjects. In WD patients, cerebellar, striatal and - to a lesser extent - cortical and thalamic rCMRGlc were significantly decreased compared with controls. Striatal rCMRGlc was significantly reduced in those 4 patients who had recently started decoppering therapy as compared with striatal rCMRGlc measured in those 10 patients with longer duration of medication. Caudate rCMRGlc correlated significantly with various signs of extrapyramidal dysfunction. Cerebellar, thalamic and cortical rCMRGlc correlated significantly with the severity of pyramidal signs. These data indicate that the PET measurement of rCMRGlc may be a useful tool to evaluate cerebral involvement in WD and to monitor the response to treatment. (orig.)
Mowat-Wilson syndrome: neurological and molecular study in seven patients
Directory of Open Access Journals (Sweden)
José Albino da Paz
2015-01-01
Full Text Available Objective To present a seven-cases serie of Mowat-Wilson syndrome (MWS. Method All patients with positive mutation for the ZEB2 were evaluated by a geneticist and a neurologist, with clinical and laboratorial characterization. Results A peculiar facies and mental retardation were present in all patients. The Denver II scale showed intense delay in all aspects, especially fine motor and adaptive. Acquired microcephaly was observed in five patients. Only one patient did not present epilepsy. Epilepsy was focal and predominating in sleep, with status epilepticus in three patients. The initial seizure was associated with fever in most patients (4/6. The EEG showed epileptic focal activity (5/7. The imaging studies revealed total agenesis (4/7 and partial agenesis of the corpus callosum (1/7. Conclusion Physicians who care for patients with mental retardation and epilepsy should be aware of SMW.
International Nuclear Information System (INIS)
Perona, J.J.
1992-01-01
Chabazite zeolites are used at ORNL for decontamination of wastewaters containing 90 Sr and 137 Cs. Treatability studies have shown that chabazite can remove trace amounts of these nuclides from wastewaters containing much higher concentrations of calcium and magnesium. The design of ion exchange columns for multicomponent systems requires a method for predicting multicomponent equilibria from binary or ternary experiments, since the number of experiments required for an empirical equilibrium model is generally not feasible. Binary interaction parameters for the Wilson equation were used to predict solid-phase activity coefficients for the five-component system, and the sum of squares of deviations between experimental and predicted solution concentrations for the data points available was calculated. The average deviation per data point for the five-component system was about the same as for the calcium-magnesium-sodium ternary system
Chiral symmetry breaking and the Banks-Casher relation in lattice QCD with Wilson quarks
Giusti, Leonardo
2009-01-01
The Banks--Casher relation links the spontaneous breaking of chiral symmetry in QCD to the presence of a non-zero density of quark modes at the low end of the spectrum of the Dirac operator. Spectral observables like the number of modes in a given energy interval are renormalizable and can therefore be computed using the Wilson formulation of lattice QCD even though the latter violates chiral symmetry at energies on the order of the inverse lattice spacing. Using numerical simulations, we find (in two-flavour QCD) that the low quark modes do condense in the expected way. In particular, the chiral condensate can be accurately calculated simply by counting the low modes on large lattices. Other spectral observables can be considered as well and have a potentially wide range of uses.
Wilson Simonal em campo: reflexões sobre o álbum México 70
Chaves, Renan Paiva; Visconti, Eduardo de Lima
2013-01-01
Análise do álbum México 70 de Wilson Simonal, lançado pela gravadora Odeon mexicana em 1970. Buscamos compreender como as dimensões internas do disco, especialmente no que tange às orientações estético-musicais, condensaram alguns conflitos simbólicos presentes no processo de internacionalização da cultura e da consolidação da indústria fonográfica no Brasil. Após articular as relações entre futebol, imprensa, música popular e Estado com uma apreciação musical de cada faixa do álbum, confront...
Shimizu, Yuya; Kuramashi, Yoshinobu
2018-02-01
We have made a detailed study of the phase structure for the lattice Schwinger model with one flavor of Wilson fermion on the (m ,g ) plane. For numerical investigation, we develop a decorated tensor renormalization method for lattice gauge theories with fermions incorporating the Grassmann tensor renormalization. Our algorithm manifestly preserves rotation and reflection symmetries. We find not only a parity-broken phase but also a Berezinskii-Kosterlitz-Thouless (BKT) transition by evaluating the central charge and an expectation value of a projection operator into the parity-odd subspace. The BKT phase boundaries converge into the degenerated doubler pole (m ,g )=(-2 ,0 ), while the parity-breaking transition line ends at the physical pole (m ,g )=(0 ,0 ). In addition, our analysis of scaling dimensions indicates that a conformal field theory with SU(2) symmetry arises on the line of m =-2 .
ESO Telescope Designer Raymond Wilson Wins Prestigious Kavli Award for Astrophysics
2010-06-01
Raymond Wilson, whose pioneering optics research at ESO made today's giant telescopes possible thanks to "active optics" technology, has been awarded the 2010 Kavli Prize in astrophysics. The founder and original leader of the Optics and Telescopes Group at ESO, Wilson shares the million-dollar prize with two American scientists, Jerry Nelson and Roger Angel. The biennial prize, presented by the Norwegian Academy of Science and Letters, the Kavli Foundation, and the Norwegian Ministry of Education and Research, was instituted in 2008 and is given to researchers who significantly advance knowledge in the fields of nanoscience, neuroscience, and astrophysics, acting as a complement to the Nobel Prize. The award is named for and funded by Fred Kavli, the Norwegian entrepreneur and philanthropist who later founded the Kavlico Corporation in the US - today one of the world's largest suppliers of sensors for aeronautic, automotive and industrial applications. Wilson, who joined ESO in 1972, strived to achieve optical perfection, developing the concept of active optics as a way to enhance the size of telescopic primary mirrors. It is the size of these mirrors that determines the ability of a telescope to gather light and study faint and distant objects. Before active optics, mirrors over six metres in diameter were impossible, being too heavy, costly, and likely to bend from gravity and temperature changes. The use of active optics, which preserves optimal image quality by continually adjusting the mirror's shape during observations, made lighter, thinner so-called "meniscus mirrors" possible. Wilson first led the implementation of active optics in the revolutionary New Technology Telescope at ESO's La Silla Observatory, and continued to develop and improve the technology until his retirement in 1993. Since then, active optics have become a standard part of modern astronomy, applied in every big telescope including ESO's Very Large Telescope (VLT), a telescope array
Wilson lines, Grassmannians and gauge invariant off-shell amplitudes in N=4 SYM
Energy Technology Data Exchange (ETDEWEB)
Bork, L.V. [Institute for Theoretical and Experimental Physics,Moscow (Russian Federation); The Center for Fundamental and Applied Research,All-Russia Research Institute of Automatics, Moscow (Russian Federation); Onishchenko, A.I. [Bogoliubov Laboratory of Theoretical Physics,Joint Institute for Nuclear Research, Dubna (Russian Federation); Moscow Institute of Physics and Technology State University,Dolgoprudny (Russian Federation); Skobeltsyn Institute of Nuclear Physics, Moscow State University,Moscow (Russian Federation)
2017-04-04
In this paper we consider tree-level gauge invariant off-shell amplitudes (Wilson line form factors) in N=4 SYM. For the off-shell amplitudes with one leg off-shell we present a conjecture for their Grassmannian integral representation in spinor helicity, twistor and momentum twistor parameterizations. The presented conjecture is successfully checked against BCFW results for MHV{sub n}, NMHV{sub 4} and NMHV{sub 5} off-shell amplitudes. We have also verified that our Grassmannian integral representation correctly reproduces soft (on-shell) limit for the off-shell gluon momentum. It is shown that the (deformed) off-shell amplitude expressions could be also obtained using quantum inverse scattering method for auxiliary gl(4|4) super spin chain.
Calculating massive 3-loop graphs for operator matrix elements by the method of hyperlogarithms
International Nuclear Information System (INIS)
Ablinger, Jakob; Blümlein, Johannes; Raab, Clemens; Schneider, Carsten; Wißbrock, Fabian
2014-01-01
We calculate convergent 3-loop Feynman diagrams containing a single massive loop equipped with twist τ=2 local operator insertions corresponding to spin N. They contribute to the massive operator matrix elements in QCD describing the massive Wilson coefficients for deep-inelastic scattering at large virtualities. Diagrams of this kind can be computed using an extended version of the method of hyperlogarithms, originally being designed for massless Feynman diagrams without operators. The method is applied to Benz- and V-type graphs, belonging to the genuine 3-loop topologies. In case of the V-type graphs with five massive propagators, new types of nested sums and iterated integrals emerge. The sums are given in terms of finite binomially and inverse binomially weighted generalized cyclotomic sums, while the 1-dimensionally iterated integrals are based on a set of ∼30 square-root valued letters. We also derive the asymptotic representations of the nested sums and present the solution for N∈C. Integrals with a power-like divergence in N-space ∝a N ,a∈R,a>1, for large values of N emerge. They still possess a representation in x-space, which is given in terms of root-valued iterated integrals in the present case. The method of hyperlogarithms is also used to calculate higher moments for crossed box graphs with different operator insertions
Calculating massive 3-loop graphs for operator matrix elements by the method of hyperlogarithms
Energy Technology Data Exchange (ETDEWEB)
Ablinger, Jakob; Schneider, Carsten [Johannes Kepler Univ., Linz (Austria). Reserach Inst. for Symbolic Computation (RISC); Bluemlein, Johannes; Raab, Clemens [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany); Wissbrock, Fabian [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany); Johannes Kepler Univ., Linz (Austria). Reserach Inst. for Symbolic Computation (RISC)
2014-02-15
We calculate convergent 3-loop Feynman diagrams containing a single massive loop equipped with twist τ=2 local operator insertions corresponding to spin N. They contribute to the massive operator matrix elements in QCD describing the massive Wilson coefficients for deep-inelastic scattering at large virtualities. Diagrams of this kind can be computed using an extended version to the method of hyperlogarithms, originally being designed for massless Feynman diagrams without operators. The method is applied to Benz- and V-type graphs, belonging to the genuine 3-loop topologies. In case of the V-type graphs with five massive propagators new types of nested sums and iterated integrals emerge. The sums are given in terms of finite binomially and inverse binomially weighted generalized cyclotomic sums, while the 1-dimensionally iterated integrals are based on a set of ∝30 square-root valued letters. We also derive the asymptotic representations of the nested sums and present the solution for N element of C. Integrals with a power-like divergence in N-space∝a{sup N}, a element of R, a>1, for large values of N emerge. They still possess a representation in x-space, which is given in terms of root-valued iterated integrals in the present case. The method of hyperlogarithms is also used to calculate higher moments for crossed box graphs with different operator insertions.
Thermodynamics in Loop Quantum Cosmology
International Nuclear Information System (INIS)
Li, L.F.; Zhu, J.Y.
2009-01-01
Loop quantum cosmology (LQC) is very powerful to deal with the behavior of early universe. Moreover, the effective loop quantum cosmology gives a successful description of the universe in the semiclassical region. We consider the apparent horizon of the Friedmann-Robertson-Walker universe as a thermodynamical system and investigate the thermodynamics of LQC in the semiclassical region. The effective density and effective pressure in the modified Friedmann equation from LQC not only determine the evolution of the universe in LQC scenario but also are actually found to be the thermodynamic quantities. This result comes from the energy definition in cosmology (the Misner-Sharp gravitational energy) and is consistent with thermodynamic laws. We prove that within the framework of loop quantum cosmology, the elementary equation of equilibrium thermodynamics is still valid.
Espaço, lugar, identidade: geografias raciais em Our Nig, de Harriet E. Wilson
Directory of Open Access Journals (Sweden)
Jose de Paiva dos Santos
2013-12-01
Full Text Available Este ensaio examina Our Nig, publicado em 1859 e considerado o primeiro romance escrito por uma mulher afrodescendente nos Estados Unidos, como uma crítica ao racismo contra os negros residentes nos estados do Norte do país, região normalmente vista pelos negros sulistas como solidária à causa abolicionista. À luz de insights provenientes da antropologia cultural e da geografia social, o texto discutirá como Harriet E. Wilson representa a formação de espaços e lugares racializados, que acabam se tornando ferramentas de dominação e exploração da mão de obra negra. Através dos abusos à personagem central do romance, a mulata Frado, Wilson discute a racialização dos lugares em uma residência em particular, a da família Bellmont. No entanto, fica evidente que o escopo crítico do romance é bem mais amplo. Além de expor ideologias raciais oitocentistas que sustentavam a demarcação racial dos espaços, ao usar a casa como metáfora para a nação, a autora traz à tona uma contradição inerente no pensamento abolicionista: por um lado, a abominação da escravidão; por outro, a segregação e a exclusão social do sujeito negro.
Seasonal movement, residency, and migratory patterns of Wilson's Snipe (Gallinago delicata)
Cline, Brittany B.; Haig, Susan M.
2011-01-01
Cross-seasonal studies of avian movement establish links between geographically distinct wintering, breeding, and migratory stopover locations, or assess site fidelity and movement between distinct phases of the annual cycle. Far fewer studies have investigated individual movement patterns within and among seasons over an annual cycle. Within western Oregon's Willamette Valley throughout 2007, we quantified intra- and interseasonal movement patterns, fidelity (regional and local), and migratory patterns of 37 radiomarked Wilson's Snipe (Gallinago delicata) to elucidate residency in a region of breeding- and wintering-range overlap. Telemetry revealed complex regional population structure, including winter residents (74%), winter transients (14%), summer residents (9%), and one year-round resident breeder (3%). Results indicated a lack of connectivity between winter and summer capture populations, some evidence of partial migration, and between-season fidelity to the region (winter-resident return; subsequent fall). Across seasons, the extent of movements and use of multiple wetland sites suggested that Wilson's Snipe were capable of exploratory movements but more regularly perceived local and fine-scale segments of the landscape as connected. Movements differed significantly by season and residency; individuals exhibited contracted movements during late winter and more expansive movements during precipitation-limited periods (late spring, summer, fall). Mean home-range size was 3.5 ± 0.93 km2 (100% minimum convex polygon [MCP]) and 1.6 ± 0.42 km2 (95% fixed kernel) and did not vary by sex; however, home range varied markedly by season (range of 100% MCPs: 1.04–7.56 km2). The results highlight the need to consider seasonal and interspecific differences in shorebird life histories and space-use requirements when developing regional wetland conservation plans.
Using Xas And Sxrf to Study Copper in Wilson Disease at the Molecular And Tissue Level
Energy Technology Data Exchange (ETDEWEB)
Ralle, M.; Blackburn, N.J.; Lutsenko, S.
2009-06-05
Wilson disease (WD) is a genetic disorder of copper metabolism associated with severe hepatic, neurological, and psychiatric abnormalities. In WD, the billiary copper excretion is impaired and copper accumulates in tissues, particularly in the liver and the brain. The affected gene, ATP7B, encodes the copper transporting ATPase, Wilson disease protein (WNDP). WNDP has six copper binding sites in the N-terminal portion of the molecule. Each site includes the conserved amino acid sequence MXCXXC, and binds 1 Cu(I) through its 2 cysteine residues. We performed X-ray absorption studies at the Cu K{sub {alpha}}-edge on the recombinant N-terminal domain of WNDP (N-WNDP). Copper was bound to N-WNDP either in vivo or in vitro in the presence of different reducing agents. We found that in N-WNDP copper is predominantly coordinated in a linear fashion by two cysteines, with the appearance of a Cu-Cu interaction when all metal binding sites are filled. Increasing amounts of reducing agents containing sulfide or phosphine groups led to binding of the exogenous ligands to copper thereby increasing the coordination number of copper from two to three. To better understand the role of copper in WD, we utilized livers of the 6-weeks-old Atp7b-/- mice (an animal model for WD) in which the copper concentration was 10--20-fold higher compared to that of the control mice. The distribution of copper in hepatocytes was evaluated by synchrotron based X-ray fluorescence microprobe (SXRF). We demonstrate that we can prepare liver slices that retain copper and can detect copper with subcellular resolution. On the same sections {mu}-XANES (spot size: 5 micron) was used to determine the oxidation state of copper.
Phenotypic and Genetic Characterization of a Cohort of Pediatric Wilson Disease Patients
Directory of Open Access Journals (Sweden)
Elnaghy Suzan
2011-06-01
Full Text Available Abstract Background In Egypt, Wilson disease seems to be under diagnosed and clinical data on large cohorts are limited. The aim of this study is to highlight the clinical, laboratory and genetic characteristics of this disease in our pediatric population as well as to report our experience with both treatment options and outcome. Methods The study included 77 patients from 50 unrelated families (62 were followed up for a mean period of 58.9 ± 6.4 months and 27 were asymptomatic siblings. Data were collected retrospectively by record analysis and patient interviews. Diagnosis was confirmed by sequencing of the ATP7B gene in 64 patients Results Our patients had unique characteristics compared to other populations. They had a younger age of onset (median: 10 years, higher prevalence of Kayser-Fleischer rings (97.6% in the symptomatic patients, low ceruloplasmin (93.5%, high rate of parental consanguinity (78.9% as well as a more severe course. 71.42% of those on long term D-penicillamine improved or were stable during the follow up with severe side effects occurring in only 11.5%. Preemptive treatment with zinc monotherapy was an effective non-toxic alternative to D-penicillamine. Homozygous mutations were found in 85.7%, yet limited by the large number of mutations detected, it was difficult to find genotype-phenotype correlations. Missense mutations were the most common while protein-truncating mutations resulted in a more severe course with higher incidence of acute liver failure and neurological symptoms. Conclusions Egyptian children with Wilson disease present with early Kayser-Fleischer rings and early onset of liver and neurological disease. The mutational spectrum identified differs from that observed in other countries. The high rate of homozygous mutations (reflecting the high rate of consanguinity may potentially offer further insights on genotype-phenotype correlation
Using XAS and SXRF to Study Copper in Wilson Disease at the Molecular and Tissue Level
Ralle, Martina; Blackburn, Ninian J.; Lutsenko, Svetlana
2007-02-01
Wilson disease (WD) is a genetic disorder of copper metabolism associated with severe hepatic, neurological, and psychiatric abnormalities. In WD, the billiary copper excretion is impaired and copper accumulates in tissues, particularly in the liver and the brain. The affected gene, ATP7B, encodes the copper transporting ATPase, Wilson disease protein (WNDP). WNDP has six copper binding sites in the N-terminal portion of the molecule. Each site includes the conserved amino acid sequence MXCXXC, and binds 1 Cu(I) through its 2 cysteine residues. We performed X-ray absorption studies at the Cu Kα-edge on the recombinant N-terminal domain of WNDP (N-WNDP). Copper was bound to N-WNDP either in vivo or in vitro in the presence of different reducing agents. We found that in N-WNDP copper is predominantly coordinated in a linear fashion by two cysteines, with the appearance of a Cu-Cu interaction when all metal binding sites are filled. Increasing amounts of reducing agents containing sulfide or phosphine groups led to binding of the exogenous ligands to copper thereby increasing the coordination number of copper from two to three. To better understand the role of copper in WD, we utilized livers of the 6-weeks-old Atp7b-/- mice (an animal model for WD) in which the copper concentration was 10-20-fold higher compared to that of the control mice. The distribution of copper in hepatocytes was evaluated by synchrotron based X-ray fluorescence microprobe (SXRF). We demonstrate that we can prepare liver slices that retain copper and can detect copper with subcellular resolution. On the same sections μ-XANES (spot size: 5 micron) was used to determine the oxidation state of copper.
Energy Technology Data Exchange (ETDEWEB)
Feng, Song; Wang, Feng; Deng, Hui; Yang, Yunfei [Yunnan Key Laboratory of Computer Technology Application/Faculty of Information Engineering and Automation, Kunming University of Science and Technology, Kunming 650500 (China); Yu, Lan, E-mail: ynkmfs@escience.cn [Department of Mechanical and Electrical Engineering, Yunnan Land and Resources Vocational College, Kunming 650217 (China)
2017-08-10
A novel time–frequency technique, called the synchrosqueezing transform (SST), is used to investigate the midterm periodic variations of magnetic fields on the solar surface. The Magnetic Plage Strength Index (MPSI) and the Mount Wilson Sunspot Index (MWSI), measured daily by the Mount Wilson Observatory between 1970 January 19 and 2012 January 22, are selected. Short-, mid, and longer-term periodicities are represented and decomposed by the SST with hardly any mode mixing. This demonstrates that the SST is a useful time–frequency analysis technique to characterize the periodic modes of helioseismic data. Apart from the fundamental modes of the annual periodicity, ∼27 day rotational cycle and ∼11 year solar cycle, the SST reveals several midterm periodicities in the two magnetic activity indices, specifically, ∼157 days (i.e., Rieger-type periodicity), and ∼1.3 and 1.7 years. The periodic modes, with 116.4 and 276.2 day periodicity in the MPSI, 108.5 and 251.6 day periodicity in the MWSI, and 157.7 day periodicity in the two indices, are in better accord with those significant periodicities derived from the Rossby waves theoretical model. This study suggests that the modes are caused by Rossby waves. For the 1.30 and 1.71 year periodicity of the MPSI, and the 1.33 and 1.67 year periodicity of the MWSI, our analysis infers that they are related to those periodicities with the same timescale in the interior of the Sun and in the high atmospheric layers.
Successful Splenectomy for Hypersplenism in Wilson's Disease: A Single Center Experience from China.
Li, Liang-Yong; Yang, Wen-Ming; Chen, Huai-Zhen; Wu, Yun-Hu; Fang, Xiang; Zhang, Jing; Wang, Zhen; Han, Yong-Sheng; Wang, Yu
2015-01-01
Splenomegaly and pancytopenia are common in Wilson's disease (WD) and splenectomy is one of the conventional treatments for splenomegaly and the associated pancytopenia. However, splenectomy remained controversial for hypersplenism in WD as it was reported that splenectomy leaded to serious emotional and neurological deterioration in WD patients with hypersplenism. In the current study, we present our experiences in 70 WD patients with hypersplenism who had undergone splenectomy, outlining the safety and efficacy of splenectomy in WD. The clinical database of 70 WD patients with hypersplenism who had undergone splenectomy in our hospital between 2009 and 2013 were reviewed and followed-up regularly. Before splenectomy, all the patients accepted a short period of anti-copper treatment with intravenous sodium 2, 3-dimercapto-1-propane sulfonate (DMPS). All the patients demonstrated a marked improvement in platelet and leucocyte counts after splenectomy. No severe postoperative complication was observed. In particular, none of the 37 patients with mixed neurologic and hepatic presentations experienced neurological deterioration after splenectomy, and none of the patients with only hepatic presentations newly developed neurological symptoms. During the one year follow-up period, no patient presented hepatic failure or hepatic encephalopathy, no hepatic patient newly developed neurological presentations, and only 3 patients with mixed neurologic and hepatic presentations suffered neurological deterioration and these 3 patients had poor compliance of anti-copper treatment. Quantative analysis of the neurological symptoms in the 37 patients using the Unified Wilson's Disease Rating Scale (UWDRS) showed that the neurological symptoms were not changed in a short-term of one week after splenectomy but significantly improved in a long-term of one year after splenectomy. Additionally, compared to that before splenectomy, the esophageal gastric varices in most patients
High pressure experimental water loop
International Nuclear Information System (INIS)
Grenon, M.
1958-01-01
A high pressure experimental water loop has been made for studying the detection and evolution of cladding failure in a pressurized reactor. The loop has been designed for a maximum temperature of 360 deg. C, a maximum of 160 kg/cm 2 and flow rates up to 5 m 3 /h. The entire loop consists of several parts: a main circuit with a canned rotor circulation pump, steam pressurizer, heating tubes, two hydro-cyclones (one de-gasser and one decanter) and one tubular heat exchanger; a continuous purification loop, connected in parallel, comprising pressure reducing valves and resin pots which also allow studies of the stability of resins under pressure, temperature and radiation; following the gas separator is a gas loop for studying the recombination of the radiolytic gases in the steam phase. The preceding circuits, as well as others, return to a low pressure storage circuit. The cold water of the low pressure storage flask is continuously reintroduced into the high pressure main circuit by means of a return pump at a maximum head of 160 kg /cm 2 , and adjusted to the pressurizer level. This loop is also a testing bench for the tight high pressure apparatus. The circulating pump and the connecting flanges (Oak Ridge type) are water-tight. The feed pump and the pressure reducing valves are not; the un-tight ones have a system of leak recovery. To permanently check the tightness the circuit has been fitted with a leak detection system (similar to the HRT one). (author) [fr
Heavy flavour corrections to polarised and unpolarised deep-inelastic scattering at 3-loop order
International Nuclear Information System (INIS)
Ablinger, J.; Round, M.; Schneider, C.; Hasselhuhn, A.
2016-11-01
We report on progress in the calculation of 3-loop corrections to the deep-inelastic structure functions from massive quarks in the asymptotic region of large momentum transfer Q 2 . Recently completed results allow us to obtain the O(a 3 s ) contributions to several heavy flavour Wilson coefficients which enter both polarised and unpolarised structure functions for lepton-nucleon scattering. In particular, we obtain the non-singlet contributions to the unpolarised structure functions F 2 (x,Q 2 ) and xF 3 (x,Q 2 ) and the polarised structure function g 1 (x,Q 2 ). From these results we also obtain the heavy flavour contributions to the Gross-Llewellyn-Smith and the Bjorken sum rules.
The running coupling from the QCD Schrödinger functional a one-loop analysis
Sint, S; Sint, Stefan; Sommer, Rainer
1996-01-01
Starting from the Schr\\"odinger functional, we give a non-perturbative definition of the running coupling constant in QCD. The spatial boundary conditions for the quark fields are chosen such that the massless Dirac operator in the classical background field has a large smallest eigenvalue. At one-loop order of perturbation theory, we determine the matching coefficient to the \\MSbar-scheme and discuss the quark mass effects in the \\beta-function. To this order, we also compute the Symanzik improvement coefficient necessary to remove the \\Oa lattice artefacts originating from the boundaries. For reasonable lattice resolutions and the standard Wilson action, lattice artefacts are found to be only weakly dependent on the lattice spacing a, while they vanish quickly with the improved action of Sheikholeslami and Wohlert.
International Nuclear Information System (INIS)
Sadeghi, Rahmat
2005-01-01
The polymer Wilson model and the polymer NRTL model have been extended for the representation of the excess enthalpy of multicomponent polymer solutions. Applicability of obtained equations in the correlation of the excess enthalpies of polymer solutions has been examined. It is found that the both models are suitable models in representing the published excess enthalpy data for the tested polymer solutions
Energy Technology Data Exchange (ETDEWEB)
Oe, Shinji, E-mail: ooes@med.uoeh-u.ac.jp; Miyagawa, Koichiro, E-mail: koichiro@med.uoeh-u.ac.jp; Honma, Yuichi, E-mail: y-homma@med.uoeh-u.ac.jp; Harada, Masaru, E-mail: msrharada@med.uoeh-u.ac.jp
2016-09-10
Copper is an essential trace element, however, excess copper is harmful to human health. Excess copper-derived oxidants contribute to the progression of Wilson disease, and oxidative stress induces accumulation of abnormal proteins. It is known that the endoplasmic reticulum (ER) plays an important role in proper protein folding, and that accumulation of misfolded proteins disturbs ER homeostasis resulting in ER stress. However, copper-induced ER homeostasis disturbance has not been fully clarified. We treated human hepatoma cell line (Huh7) and immortalized-human hepatocyte cell line (OUMS29) with copper and chemical chaperones, including 4-phenylbutyrate and ursodeoxycholic acid. We examined copper-induced oxidative stress, ER stress and apoptosis by immunofluorescence microscopy and immunoblot analyses. Furthermore, we examined the effects of copper on carcinogenesis. Excess copper induced not only oxidative stress but also ER stress. Furthermore, excess copper induced DNA damage and reduced cell proliferation. Chemical chaperones reduced this copper-induced hepatotoxicity. Excess copper induced hepatotoxicity via ER stress. We also confirmed the abnormality of ultra-structure of the ER of hepatocytes in patients with Wilson disease. These findings show that ER stress plays a pivotal role in Wilson disease, and suggests that chemical chaperones may have beneficial effects in the treatment of Wilson disease.
Ojelabi, Adedokun Oluwafemi; Graham, Yitka; Haighton, Catherine; Ling, Jonathan
2017-12-11
A conceptual model approach to clarify the elements of health-related quality of life (HRQL), their determinants and causal pathways is needed to aid researchers, health practitioners and policy makers in their bid to improve HRQL outcomes in patients. The aim of this systematic review was to appraise empirical evidence on the performance of the Wilson and Cleary Model of HRQL. We conducted a search of MEDLINE, Science Direct, PsyARTICLES and CINAHL databases to identify articles that used Wilson and Cleary model to examine HRQL in chronic diseases. A narrative synthesis was employed in the review of the articles. Evidence supports linkages between adjacent concepts and between non-adjacent concepts of the Wilson and Cleary model indicating that in practice there is a need to examine relationships among constructs - or to consider interventions in terms of - both with and without mediators. Symptoms status has the highest magnitude of relative impact on health-related quality of life. The Wilson and Cleary model demonstrated good features suitable for evaluating health-related quality of life in chronic diseases.
Vaishali Chandrashekhar; Jaideep; Medha K; Sandhya P; Manish
2015-01-01
BACKGROUND : This study was carried out to evaluate usefulness of preoperative Mallampati & Wilson’s score grading as a predictor for difficult laryngoscopy & intubation . AIMS : To determine the accuracy of the modified Mallampati test and Wilson score for predicting difficult tracheal intubation and correlation with Cormack Lehane grading . METHODS : This prospective randomized cross sectional Study carried out in 200 patients , poste...
2013-08-21
... DEPARTMENT OF HEALTH AND HUMAN SERVICES Office of Refugee Resettlement [C.F.D.A. Number: 93.566] Notice of FY 2013 Refugee Social Services Formula Awards to States and Wilson/Fish Alternative Project Grantees AGENCY: Office of Refugee Resettlement, ACF, HHS. ACTION: Notice of awards. SUMMARY: The Office of...
2012-08-30
... DEPARTMENT OF HEALTH AND HUMAN SERVICES Office of Refugee Resettlement [C.F.D.A. Number: 93.566] Notice of FY 2012 Refugee Social Services Formula Awards to States and Wilson/Fish Alternative Project Grantees AGENCY: Office of Refugee Resettlement, ACF, HHS. ACTION: Notice of awards. CFDA Number: 93.566...