WorldWideScience

Sample records for boson discovery potential

  1. ATLAS DISCOVERY POTENTIAL FOR A HEAVY CHARGED HIGGS BOSON.

    Energy Technology Data Exchange (ETDEWEB)

    ASSAMAGAN,K.A.; COADOU,Y.; DEANDREA,A.

    2002-02-01

    The sensitivity of the ATLAS detector to the discovery of a heavy charged Higgs boson is presented. Assuming a heavy SUSY spectrum, the most promising channels above the top quark mass are H{sup {+-}} {yields} tb and h{sup {+-}} {yields} {tau}{sup {+-}}{nu}{sub {tau}} which provide coverage in the low and high tan {beta} regions up to {approx} 600 GeV. The achievable precisions on the charged Higgs mass and tan {beta} determination are also discussed. The H{sup {+-}} {yields} W{sup {+-}}h{sup 0} channel, though restricted to a small MSSM parameter space, shows a viable signal in NMSSM where the parameter space is less constrained. The observation of the channel H{sup -} {yields} {tau}{sub L}{sup -} {nu}{sub {tau}} + c.c. may constitute a distinctive evidence for models with singlet neutrinos in large extra dimensions.

  2. Discovery of the higgs boson

    CERN Document Server

    Sharma, Vivek

    2016-01-01

    The recent observation of the Higgs boson has been hailed as the scientific discovery of the century and led to the 2013 Nobel Prize in physics. This book describes the detailed science behind the decades-long search for this elusive particle at the Large Electron Positron Collider at CERN and at the Tevatron at Fermilab and its subsequent discovery and characterization at the Large Hadron Collider at CERN. Written by physicists who played leading roles in this epic search and discovery, this book is an authoritative and pedagogical exposition of the portrait of the Higgs boson that has emerged from a large number of experimental measurements. As the first of its kind, this book should be of interest to graduate students and researchers in particle physics.

  3. Discovery of the Higgs boson

    CERN Document Server

    Sharma, Vivek

    2016-01-01

    The recent observation of the Higgs boson has been hailed as the scientific discovery of the century and led to the 2013 Nobel Prize in physics. This book describes the detailed science behind the decades-long search for this elusive particle at the Large Electron Positron Collider at CERN and at the Tevatron at Fermilab and its subsequent discovery and characterization at the Large Hadron Collider at CERN. Written by physicists who played leading roles in this epic search and discovery, this book is an authoritative and pedagogical exposition of the portrait of the Higgs boson that has emerged from a large number of experimental measurements. As the first of its kind, this book should be of interest to graduate students and researchers in particle physics.

  4. Improving the discovery potential of charged Higgs bosons at the Tevatron and large hadron collider

    Indian Academy of Sciences (India)

    Stefano Moretti

    2003-02-01

    We outline several improvements to the experimental analyses carried out at Tevatron (Run 2) or simulated in view of the large hadron collider (LHC) that could increase the scope of CDF/D0 and ATLAS/CMS in detecting charged Higgs bosons.

  5. Discovery Potential for the SM Higgs Boson in the $H \\to ZZ^{(*)} \\to e^+ e^- e^+ e^-$ Decay Channel

    CERN Document Server

    Baffioni, Stephanie; Ferri, Federico; Godinovic, Nikola; Meridiani, Paolo; Puljak, Ivica; Salerno, Roberto; Sirois, Yves

    2006-01-01

    A prospective analysis is presented for the discovery and for the mass and cross-section measurements of the Standard Model Higgs boson in the CMS experiment at the LHC collider. The analysis focuses on the p p --> H + X --> ZZ(*) + X --> e+e-e+e- + X channel for Higgs boson masses in the range from about 120 GeV/c^2 to about 300 GeV/c^2. It relies on a full simulation of the detector response and usage of new detailed electron reconstruction tools. Emphasis is put on realistic strategies for the evaluation of experimental systematics and control of physics background processes. For an integrated LHC luminosity of 30 fb^{-1}, a Standard Model Higgs boson would be observed in the e+e-e+e- channel with a significance above 3 standard deviations for masses m_H in the range from about 130 to 160 GeV/c^2 and above 180 GeV/c^2. A discovery with a significance above 5 standard deviations is possible for this integrated luminosity around m_H = 150 GeV/c^2 and in the range from about 190 to 300 GeV/c^2. The mass (cros...

  6. Light Higgs boson discovery from fermion mixing

    Science.gov (United States)

    Aguilar–Saavedra, Juan Antonio

    2006-12-01

    We evaluate the LHC discovery potential for a light Higgs boson in tbar tH (→ellνbbar bbbar bjj) production, within the Standard Model and if a new Q = 2/3 quark singlet T with a moderate mass exists. In the latter case, T pair production with decays Tbar T→W+b Hbar t/Ht W-bar b→W+bW-bar bH provides an important additional source of Higgs bosons giving the same experimental signature, and other decay modes Tbar T→Ht Hbar t→W+bW-bar bHH, Tbar T→Zt Hbar t/Ht Zbar t→W+bW-bar bHZ further enhance this signal. Both analyses are carried out with particle-level simulations of signals and backgrounds, including tbar t plus n = 0,...,5 jets which constitute the main background by far. Our estimate for SM Higgs discovery in tbar tH production, 0.4σ significance for MH = 115 GeV and an integrated luminosity of 30 fb-1, is similar to the most recent ones by CMS which also include the full tbar tnj background. We show that, if a quark singlet with a mass mT = 500 GeV exists, the luminosity required for Higgs discovery in this final state is reduced by more than two orders of magnitude, and 5σ significance can be achieved already with 8 fb-1. This new Higgs signal will not be seen unless we look for it: with this aim, a new specific final state reconstruction method is presented. Finally, we consider the sensitivity to search for Q = 2/3 singlets. The combination of these three decay modes allows to discover a 500 GeV quark with 7 fb-1 of luminosity.

  7. Study of the Higgs boson discovery potential in the process pp{yields}Hqq, H{yields}{tau}{sup +}{tau}{sup -} with the ATLAS detector

    Energy Technology Data Exchange (ETDEWEB)

    Groh, Manfred

    2009-04-27

    The subject of this work is the evaluation of the discovery potential of the ATLAS detector at the Large Hadron Collider for the Standard Model Higgs boson in vector-boson fusion production and a subsequent decay into a {tau}-lepton pair. This is one of the most promising discovery channels of the Higgs boson in the low mass range, which is the mass range favored from precision measurements of the electroweak interaction. The decay modes where both {tau} leptons decay leptonically and where one {tau} lepton decays leptonically and the other one hadronically are studied in this thesis. The main objective was to investigate possible improvements upon earlier cut-based analyses by using additional discriminating variables as well as by applying multivariate analysis methods which take into account correlations between the variables. The variables are carefully selected in order to avoid correlations with the reconstructed invariant {tau}{tau} mass. In an intermediate step, the sequential signal selection cuts have been optimized for maximum signal significance. With this strategy, one can expect to discover the Higgs boson with {>=}5{sigma} significance in the mass range 115 GeV{<=} m{sub H}{<=}135 GeV with an integrated luminosity of 30 fb{sup -1} corresponding to the first three years of ATLAS operation. The maximum signal significance of 5.9{sigma} is obtained for a Higgs mass of 120 GeV. Significant further improvement was found with multivariate selection methods. The best results are obtained with an Artificial Neural Network algorithm. The mass range for the {>=}5{sigma} Higgs discovery with 30 fb{sup -1} is extended to 110 GeV with a maximum signal significance of 6.5 {sigma} at m{sub H}=125 GeV. Systematic uncertainties are studied in detail for both methods and are included in the above predictions of the signal significance. The largest uncertainty is due to the jet energy scale. In the case of using only Monte Carlo simulations for estimating the

  8. Discovery of the intermediate W boson

    CERN Multimedia

    1983-01-01

    Press conference on 25 January 1983 when the announcement was made of the discovery of the intermediate W boson at CERN. From right to left: Carlo Rubbia, spokesman of the UA1 experiment; Simon van der Meer, responsible for developing the stochastic cooling technique; Herwig Schopper, Director- General of CERN; Erwin Gabathuler, Research Director at CERN, and Pierre Darriulat, spokesman of the UA2 experiment, whose results confirmed those from Carlo Rubbia's experiment.

  9. The Higgs Boson Search and Discovery

    Science.gov (United States)

    Bernardi, Gregorio; Konigsberg, Jacobo

    2016-10-01

    We present a brief account of the search for the Higgs boson at the three major colliders that have operated over the last three decades: LEP, the Tevatron, and the LHC. The experimental challenges encountered stemmed from the distinct event phenomenology as determined by the colliders energy and the possible values for the Higgs boson mass, and from the capability of these colliders to deliver as much collision data as possible to fully explore the mass spectrum within their reach. Focusing more on the hadron collider searches during the last decade, we discuss how the search for the Higgs boson was advanced through mastering the experimental signatures of standard theory backgrounds, through the comprehensive utilization of the features of the detectors involved in the searches, and by means of advanced data analysis techniques. The search culminated in 2012 with the discovery, by the ATLAS and CMS collaborations, of a Higgs-like particle with mass close to 125 GeV, confirmed more recently to have properties consistent with those expected from the standard theory Higgs boson.

  10. The Higgs Boson Search and Discovery

    CERN Document Server

    Bernardi, Gregorio

    2016-01-01

    We present a brief account of the search for the Higgs boson at the three major colliders that have operated over the last three decades: LEP, the Tevatron, and the LHC. The experimental challenges encountered stemmed from the distinct event phenomenology as determined by the colliders energy and the possible values for the Higgs boson mass, and from the capability of these colliders to deliver as much collision data as possible to fully explore the mass spectrum within their reach. Focusing more on the hadron collider searches during the last decade, we discuss how the search for the Higgs boson was advanced through mastering the experimental signatures of standard theory backgrounds, through the comprehensive utilization of the features of the detectors involved in the searches, and by means of advanced data analysis techniques. The search culminated in 2012 with the discovery, by the ATLAS and CMS collaborations, of a Higgs-like particle with mass close to 125 GeV, confirmed more recently to have propertie...

  11. Discovery potential of Higgs boson pair production through final states at a 100 TeV collider

    Science.gov (United States)

    Zhao, Xiaoran; Li, Qiang; Li, Zhao; Yan, Qi-Shu

    2017-02-01

    We explore the discovery potential of Higgs pair production at a 100 TeV collider via full leptonic mode. The same mode can be explored at the LHC when Higgs pair production is enhanced by new physics. We examine two types of fully leptonic final states and propose a partial reconstruction method, which can reconstruct some useful kinematic observables. It is found that the m T2 variable determined by this reconstruction method and the reconstructed visible Higgs mass are crucial to discriminate the signal and background events. It is also noticed that a new variable, denoted as Δm, which is defined as the mass difference of two possible combinations, is very useful as a discriminant. To examine the detector effects, we consider seven detector setups for a 100 TeV collider and investigate the changes in the sensitivity, and we find that lepton isolation and the minimal lepton P t cut are crucial in order to reduce the integrated luminosity. Supported by Natural Science Foundation of China (11175251, 11305179, 11675185, 11475180, 11575005) The work of Q. Li and Q.S. Yan is partially supported by CAS Center for Excellence in Particle Physics (CCEPP), X. Zhao is partially supported by the European Union as part of the FP7 Marie Curie Initial Training Network MCnetITN (PITN-GA-2012-315877).

  12. The discovery and measurements of a Higgs boson.

    Science.gov (United States)

    Gianotti, F; Virdee, T S

    2015-01-13

    In July 2012, the ATLAS and CMS collaborations at CERN's Large Hadron Collider announced the discovery of a Higgs-like boson, a new heavy particle at a mass more than 130 times the mass of a proton. Since then, further data have revealed its properties to be strikingly similar to those of the Standard Model Higgs boson, a particle expected from the mechanism introduced almost 50 years ago by six theoreticians including British physicists Peter Higgs from Edinburgh University and Tom Kibble from Imperial College London. The discovery is the culmination of a truly remarkable scientific journey and undoubtedly the most significant scientific discovery of the twenty-first century so far. Its experimental confirmation turned out to be a monumental task requiring the creation of an accelerator and experiments of unprecedented capability and complexity, designed to discern the signatures that correspond to the Higgs boson. Thousands of scientists and engineers, in each of the ATLAS and CMS teams, came together from all four corners of the world to make this massive discovery possible.

  13. Discovery of the Higgs Boson Decaying to Two Photons

    CERN Document Server

    AUTHOR|(CDS)2075371; Branson, James; Pieri, Marco

    2014-09-10

    The Standard Model (SM) of particle physics fundamentally relies on the existence of the Higgs boson. This massive particle is a relic of the underlying and hidden Higgs field, whose transformation into the Higgs boson provides mass to weak bosons and all massive fermions in the SM. This particle has been long-sought and finally using data from proton-proton collisions at the LHC, CMS and ATLAS experiments have discovered a particle which is compatible with the SM Higgs boson. Presented here is the development of one of the discovery channels, $\\mathrm{H}\\rightarrow\\gamma\\gamma$, and the final $\\mathrm{H}\\rightarrow\\gamma\\gamma$ analysis and results using the full luminosity of the LHC Run 1 dataset $\\sim$25 $\\mathrm{fb}^{-1}$ at 7 or 8 TeV center of mass energy. The observed (expected) significance of this di-photon excess in the final analysis is $5.7\\sigma$ ($5.2\\sigma$) with a measured signal strength of $\\sigma / \\sigma_{SM} = 1.14^{+0.26}_{-0.23}$. The mass of this Higgs boson is not predicted by t...

  14. Study of the Higgs boson discovery potential in the process pp{yields}H/A{yields}{mu}{sup +}{mu}{sup -}/{tau}{sup +}{tau}{sup -} with the ATLAS detector

    Energy Technology Data Exchange (ETDEWEB)

    Dedes, Georgios

    2008-04-22

    In this thesis, the discovery potential of the ATLAS experiment at the Large Hadron Collider (LHC) at CERN for the heavy neutral Higgs bosons H/A of theMinimal Supersymmetric extension of the Standard Model of particle physics (MSSM) in the decay channels H/A{yields}{tau}{sup +}{tau}{sup -}{yields}e/{mu}+X and H/A{yields}{mu}{sup +}{mu}{sup -} has been studied. The ATLAS detector is designed to study the full spectrum of the physics phenomena occuring in the proton-proton collisions at 14 TeV center-of-mass energy and to provide answers to the question of the origin of particle masses and of electroweak symmetry breaking. For the studies, the ATLAS muon spectrometer plays an important role. The spectrometer allows for a precise muon momentum measurement independently of other ATLAS subdetectors. The performance of the muon spectrometer depends strongly on the performance of the muon tracking detectors, the Monitored Drift Tube Chambers (MDT). Computer programs have been developed in order to test and verify the ATLAS muon spectrometer simulation, an essential ingredient for data analysis. In addition, dedicated programs for the monitoring of the quality of the data collected by the muon spectrometer have been developed and tested with data from cosmic ray muons. High-quality cosmic ray muon data have been used for the calibration of the MDT-chambers. A new calibration method, called analytical autocalibration, has been tested. The proposed method achieved the required accuracy of 20 {mu}m in the determination of the space-to-drift-time relationship of the drift tubes of the MDT chambers with only 2000 muon tracks per chamber. Reliable muon detector simulation and calibration are essential for the study of the MSSM Higgs boson decays H/A{yields}{tau}{sup +}{tau}{sup -}{yields}e/{mu}+X and H/A{yields}{mu}{sup +}{mu}{sup -} and of the corresponding background processes. The signal selection and background rejection requirements have been optimized for maximum signal

  15. Discovery of the Higgs boson by the ATLAS and CMS experiments at the LHC

    CERN Document Server

    Wang, HaiChen

    2014-01-01

    The Standard Model (SM) Higgs boson was predicted by theorists in the 1960s during the development of the electroweak theory. Prior to the startup of the CERN Large Hadron Collider (LHC), experimental searches found no evidence of the Higgs boson. In July 2012, the ATLAS and CMS experiments at the LHC reported the discovery of a new boson in their searches for the SM Higgs boson. Subsequent experimental studies have revealed the spin-0 nature of this new boson and found its couplings to SM particles consistent to those of a Higgs boson. These measurements confirmed the newly discovered boson is indeed a Higgs boson. More measurements will be performed to compare the properties of the Higgs boson with the SM predictions.

  16. Bosonization

    CERN Document Server

    1994-01-01

    Bosonization is a useful technique for studying systems of interacting fermions in low dimensions. It has applications in both particle and condensed matter physics.This book contains reprints of papers on the method as used in these fields. The papers range from the classic work of Tomonaga in the 1950's on one-dimensional electron gases, through the discovery of fermionic solitons in the 1970's, to integrable systems and bosonization on Riemann surfaces. A four-chapter pedagogical introduction by the editor should make the book accessible to graduate students and experienced researchers alik

  17. Present status and future prospects for a Higgs boson discovery at the Tevatron and LHC

    CERN Document Server

    Haber, Howard E

    2010-01-01

    Discovering the Higgs boson is one of the primary goals of both the Tevatron and the Large Hadron Collider (LHC). The present status of the Higgs search is reviewed and future prospects for discovery at the Tevatron and LHC are considered. This talk focuses primarily on the Higgs boson of the Standard Model and its minimal supersymmetric extension. Theoretical expectations for the Higgs boson and its phenomenological consequences are reviewed.

  18. Bosonic Partition Functions at Nonzero (Imaginary) Chemical Potential

    CERN Document Server

    Kellerstein, M

    2016-01-01

    We consider bosonic random matrix partition functions at nonzero chemical potential and compare the chiral condensate, the baryon number density and the baryon number susceptibility to the result of the corresponding fermionic partition function. We find that as long as results are finite, the phase transition of the fermionic theory persists in the bosonic theory. However, in case that bosonic partition function diverges and has to be regularized, the phase transition of the fermionic theory does not occur in the bosonic theory, and the bosonic theory is always in the broken phase.

  19. The theoretical physics ecosystem behind the discovery of the Higgs boson

    CERN Document Server

    Wells, James D

    2016-01-01

    The discovery of the Higgs boson in 2012 was one of the most significant developments of science in the last half century. A simplified history has Peter Higgs positing it in the mid-1960s followed by a long wait while experimentalists progressively turned up collider energies until it appeared several decades later. However, in order for both the hypothesis and the experimental discovery to occur, a vast and complex theory ecosystem had to thrive in the years before Higgs's hypothesis and in the years that followed, building up to its discovery. It is further claimed that the Higgs boson hypothesis was an immoderate speculation, and therefore faith in theory argumentation and speculation was mandatory for the discovery program to proceed and reach its fulfillment. The Higgs boson could not have been discovered experimentally by accident.

  20. Discovery and Characterization of a Higgs boson using four-lepton events from the CMS

    Energy Technology Data Exchange (ETDEWEB)

    Martin, Christopher Blake [Johns Hopkins Univ., Baltimore, MD (United States)

    2015-07-01

    A new particle decaying to a pair of vector bosons was discovered in 2012 by the ATLAS and CMS experiments at the Large Hadron Collider. In the wake of this discovery a rush of measurements was made to characterize this particle. The fourlepton final state has been instrumental in both the discovery and characterization of this new particle. With only about 20 events seen in the resonance peak at 125 GeV the CMS experiment has been able to make considerable progress in characterizing the Higgs-like boson using the wealth of information in this final state in concert with other decay modes. In addition to the search for this new boson we present three recent results in the study of the Higgs-like boson properties: studies of the production mode, total width, and spin-parity quantum numbers.

  1. The search and discovery of the Higgs boson a brief introduction to particle physics

    CERN Document Server

    Flores Castillo, Luis Roberto

    2015-01-01

    This book provides a general description of the search for and discovery of the Higgs boson (particle) at CERN's Large Hadron Collider. The goal is to provide a relatively brief overview of the issues, instruments and techniques relevant for this search; written by a physicist who was directly involved. The Higgs boson may be the one particle that was studied the most before its discovery and the story from postulation in 1964 to detection in 2012 is a fascinating one. The story is told here while detailing the fundamentals of particle physics.

  2. Resummation of Goldstone boson contributions to the MSSM effective potential

    CERN Document Server

    Kumar, Nilanjana

    2016-01-01

    We discuss the resummation of the Goldstone boson contributions to the effective potential of the Minimal Supersymmetric Standard Model (MSSM). This eliminates the formal problems of spurious imaginary parts and logarithmic singularities in the minimization conditions when the tree-level Goldstone boson squared masses are negative or approach zero. The numerical impact of the resummation is shown to be almost always very small. We also show how to write the two-loop minimization conditions so that Goldstone boson squared masses do not appear at all, and so that they can be solved without iteration.

  3. Resummation of Goldstone boson contributions to the MSSM effective potential

    Science.gov (United States)

    Kumar, Nilanjana; Martin, Stephen P.

    2016-07-01

    We discuss the resummation of the Goldstone boson contributions to the effective potential of the minimal supersymmetric Standard Model. This eliminates the formal problems of spurious imaginary parts and logarithmic singularities in the minimization conditions when the tree-level Goldstone boson squared masses are negative or approach zero. The numerical impact of the resummation is shown to be almost always very small. We also show how to write the two-loop minimization conditions so that Goldstone boson squared masses do not appear at all, and so that they can be solved without iteration.

  4. What is the probability of the Higgs boson discovery?

    Energy Technology Data Exchange (ETDEWEB)

    Unzicker, Alexander [Pestalozzi-Gymnasium Muenchen (Germany)

    2010-07-01

    The standard model of particle physics requires the existence of the Higgs boson which provides a mechanism for the appearance of masses. Its detection is one of the most important goals of high energy physics, and enormous efforts have been undertaken at Tevatron and specially at the Large Hadron Collider. But how sure can we be that the Higgs exits at all? At such controversial questions, the German philosopher Immanuel Kant recommended a bet, and nowadays this can be realized using online prediction markets like Intrade.com. Such platforms have been proven useful for giving estimates of unknown probabilities, and the application for evaluating scientific research is discussed in general.

  5. Particle Physics after the Higgs-Boson Discovery: Opportunities for the Large Hadron Collider

    CERN Document Server

    Quigg, Chris

    2015-01-01

    The first run of the Large Hadron Collider at CERN brought the discovery of the Higgs boson, an apparently elementary scalar particle with a mass of 125 GeV, the avatar of the mechanism that hides the electroweak symmetry. A new round of experimentation is beginning, with the energy of the proton--proton colliding beams raised to 6.5 TeV per beam, from 4 TeV at the end of the first run. This article summarizes what we have learned about the Higgs boson, and calls attention to some issues that will be among our central concerns in the near future.

  6. Nonuniversal gaugino masses and seminatural supersymmetry in view of the Higgs boson discovery

    Energy Technology Data Exchange (ETDEWEB)

    Martin, Stephen P. [Santa Barbara, KITP

    2014-02-20

    I consider models with non-universal gaugino masses at the gauge coupling unification scale, taking into account the Higgs boson discovery. Viable regions of parameter space are mapped and studied in the case of non-universality following from an F-term in a linear combination of singlet and adjoint representations of SU(5). I consider, in particular, "semi-natural" models that have small \\mu, with gaugino masses dominating the supersymmetry breaking terms at high energies. Higgsino-like particles are then much lighter than all other superpartners, and the prospects for discovery at the Large Hadron Collider can be extremely challenging.

  7. Scalar meson mass from renormalized One Boson Exchange Potential

    CERN Document Server

    Cordon, A Calle

    2008-01-01

    We determine the mass and strength of the scalar meson from NN scattering data by renormalizing the One Boson Exchange Potential. This procedure provides a great insensitivity to the unknown short distance interaction making the vector mesons marginally important and allowing for SU(3) couplings in the 1S0 channel. The scalar meson parameters are tightly constrained by low energy np. We discuss whether this scalar should be compared to the recent findings based on the Roy equations analysis of pipi scattering.

  8. Universal Behavior of Few-Boson Systems Using Potential Models

    Science.gov (United States)

    Kievsky, A.; Viviani, M.; Álvarez-Rodríguez, R.; Gattobigio, M.; Deltuva, A.

    2017-03-01

    The universal behavior of a three-boson system close to the unitary limit is encoded in a simple dependence of many observables in terms of few parameters. For example the product of the three-body parameter κ _* and the two-body scattering length a, κ _* a depends on the angle ξ defined by E_3/E_2=tan ^2ξ . A similar dependence is observed in the ratio a_{AD}/a with a_{AD} the boson-dimer scattering length. We use a two-parameter potential to determine this simple behavior and, as an application, to compute a_{AD} for the case of three ^4He atoms.

  9. Influence of Finite Chemical Potential on Critical Boson Mass in QED3

    Institute of Scientific and Technical Information of China (English)

    ZHANG Yun-Qiang; LI Zhen; FENG Hong-Tao

    2007-01-01

    Using the coupled Dyson-Schwinger equation for the fermion propagator at finite chemical potential μ,we investigate the fermion chiral condensate when the gauge boson mass is nonzero in QED3. We show that the chiral symmetry restores when the boson mass is large enough, and the critical boson mass depends little on μ.

  10. Finite Theories predictions vs. the Discovery of a Higgs-like Boson at the LHC

    Directory of Open Access Journals (Sweden)

    Heinemeyer Sven

    2014-04-01

    Full Text Available Finite Unified Theories (FUTs have proven very successful so far. In particular, they predicted the top quark mass one and half years before its experimental discovery, while around five years ago confronting their predictions with the values of the top and bottom quark masses at the time, as well as with other low-energy experimental results, a light Higgs-boson in the mass range ~ 121–126 GeV was predicted, in striking agreement with the recent discovery of a Higgs like state at ATLAS and CMS. FUTs are N = 1 supersymmetric Grand Unified Theories, which can be made all-loop finite based on the principle of reduction of couplings, which in turn provides them with a large predictive power. Here we review a FUT model based on SU(5 as gauge group. It is worth noting that this model naturally predicted a relatively heavy spectrum with the coloured supersymmetric particles above 1.5 TeV, consistent with the non-observation of those particles at the LHC, as well as a large tan β. Recently, restricting further the parameter space of this FUT model according to the discovery of a Higgs-like state and B-physics observables, we found predictions for the rest of the Higgs masses and s-spectrum.

  11. Finite theories after the discovery of a Higgs-like boson at the LHC

    Energy Technology Data Exchange (ETDEWEB)

    Heinemeyer, Sven, E-mail: Sven.Heinemeyer@cern.ch [Instituto de Fisica de Cantabria (CSIC-UC), Edificio Juan Jorda, Avda. de Los Castros s/n, 39005 Santander (Spain); Mondragon, Myriam, E-mail: myriam@fisica.unam.mx [Instituto de Fisica, Universidad Nacional Autonoma de Mexico, Apdo. Postal 20-364, Mexico 01000 D.F. (Mexico); Zoupanos, George, E-mail: George.Zoupanos@cern.ch [Max-Planck-Institut fuer Physik (Werner-Heisenberg-Institut), Foehringer Ring 6, 80805 Muenchen (Germany); Arnold-Sommerfeld-Center fuer Theoretische Physik, Department fuer Physik, Ludwig-Maximilians-Universitaet Muenchen, Theresienstrasse 37, 80333 Muenchen (Germany); Theory Group, Physics Department, CERN, Geneva (Switzerland)

    2013-01-29

    Finite Unified Theories (FUTs) are N=1 supersymmetric Grand Unified Theories (GUTs) which can be made finite to all-loop orders, based on the principle of reduction of couplings, and therefore are provided with a large predictive power. Confronting the predictions of SU(5) FUTs with the top and bottom quark masses and other low-energy experimental constraints a light Higgs boson mass in the range M{sub h}{approx}121-126 GeV was predicted, in striking agreement with the recent discovery of a Higgs-like state around {approx}125.7 GeV at ATLAS and CMS. Furthermore the favoured model, a finiteness constrained version of the MSSM, naturally predicts a relatively heavy spectrum with coloured supersymmetric particles above {approx}1.5 TeV, consistent with the non-observation of those particles at the LHC. Restricting further the best FUT's parameter space according to the discovery of a Higgs-like state and B-physics observables we find predictions for the rest of the Higgs masses and the s-spectrum.

  12. Finite theories before and after the discovery of a Higgs boson at the LHC

    Energy Technology Data Exchange (ETDEWEB)

    Heinemeyer, S. [Instituto de Fisica de Cantabria (CSIC-UC), Santander (Spain); Mondrag, M. [Instituto de Fisica, Universidad Nacional Autonoma de Mexico (Mexico); Zoupanos, G. [Arnold-Sommerfeld-Center fuer Theoretische Physik, Department fuer Physik, Ludwig-Maximilians-Universitaet Muenchen (Germany); Max-Planck-Institut fuer Physik (Werner-Heisenberg-Institut), Muenchen (Germany); Departamento de Fisica Teorica and Instituto de Fisica Teorica, IFT-UAM/CSIC, Universidad Autonoma de Madrid, Cantoblanco (Spain)

    2013-11-15

    Finite Unified Theories (FUTs) are N = 1 supersymmetric Grand Unified Theories (GUTs) which can be made finite to all-loop orders, based on the principle of reduction of couplings, and therefore are provided with a large predictive power. Confronting the predictions of SU(5) FUTs with the top and bottom quark masses and other low-energy experimental constraints a light Higgs-boson mass in the range M{sub h} {proportional_to} 121-126 GeV was predicted, in striking agreement with the recent discovery of a Higgs-like state around {proportional_to} 125.5 GeV at ATLAS and CMS. Furthermore the favoured model, a finiteness constrained version of the MSSM, naturally predicts a relatively heavy spectrum with coloured supersymmetric particles above {proportional_to} 1.5 TeV, consistent with the non-observation of those particles at the LHC. Restricting further the best FUT's parameter space according to the discovery of a Higgs-like state and B-physics observables we find predictions for the rest of the Higgs masses and the supersymmetric particle spectrum. (Copyright copyright 2013 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  13. $3d$ fermion-boson map with imaginary chemical potential

    CERN Document Server

    Filothodoros, E G; Vlachos, N D

    2016-01-01

    We study the three-dimensional $U(N)$ Gross-Neveu and CP$^{N-1}$ models in the canonical formalism with fixed $U(1)$ charge. For large-$N$ this is closely related to coupling the models to abelian Chern-Simons in a monopole background. We show that the presence of the imaginary chemical potential for the $U(1)$ charge makes the phase structure of the models remarkably similar. We calculate their respective large-$N$ free energy densities and show that they are mapped into each other in a precise way. Intriguingly, the free energy map involves the Bloch-Wigner function and its generalizations introduced by Zagier. We expect that our results are connected to the recently discussed $3d$ bosonization.

  14. Discovery Potential of h/A/H to tau+ tau- to l+l- 4nu

    CERN Document Server

    The ATLAS collaboration

    2009-01-01

    This note describes a study of the discovery potential for the supersymmetric Higgs bosons h/H/A in proton-proton collisions at a center-of-mass energy of 14 TeV in final states with tau lepton pairs with the ATLAS detector at the LHC. The Higgs bosons are produced in association with b quarks and decay into a tautau final state where both tau leptons decay leptonically. The signature of Higgs bosons with masses between 110 and 450 GeV is analyzed and the discovery potential is assessed. The analysis is based on an integrated luminosity of 30 fb−1. All results are obtained using full simulation of the ATLAS detector. No pile-up or cavern background has been considered in this analysis. In addition a procedure for estimating the shape and the normalization of the irreducible Z → tau+ tau- background from data is investigated. The discovery potential as a function of mA and tan beta is shown for the mh-max MSSM benchmark scenario.

  15. The discovery potential of laser polarization experiments

    Energy Technology Data Exchange (ETDEWEB)

    Ahlers, Markus [Oxford Univ. (United Kingdom). Rudolf Peierls Centre for Theoretical Physics; Jaeckel, Joerg [Durham Univ. (United Kingdom). Inst. for Particle Physics and Phenomenology; Ringwald, Andreas [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany)

    2008-12-15

    Currently, a number of experiments are searching for vacuum magnetic birefringence and dichroism, i.e. for dispersive and absorptive features in the propagation of polarized light along a transverse magnetic field in vacuum. In this note we calculate the Standard Model contributions to these signatures, thereby illuminating the discovery potential of such experiments in the search for new physics. We discuss the three main sources for a Standard Model contribution to a dichroism signal: photon splitting, neutrino pair production and production of gravitons. (orig.)

  16. Supersolid Phase in One-Dimensional Hard-Core Boson Hubbard Model with a Superlattice Potential

    Institute of Scientific and Technical Information of China (English)

    GUO Huai-Ming; LIANG Ying

    2008-01-01

    The ground state of the one-dimensional hard-core boson Hubbard model with a superlattice potential is studied by quantum Monte Carlo methods. We demonstrate that besides the CDW phase and the Mort insulator phase, the supersolid phase emerges due to the presence of the superlattice potential, which reflects the competition with the hopping term. We also study the densities of sublattices and have a clear idea about the distribution of the bosons on the lattice.

  17. The electroweak fit of the standard model after the discovery of a new boson at the LHC

    Energy Technology Data Exchange (ETDEWEB)

    Baak, M.; Hoecker, A.; Schott, M. [European Organization for Nuclear Research (CERN), Geneva (Switzerland); Goebel, M.; Kennedy, D.; Moenig, K. [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany); Haller, J.; Kogler, R. [Hamburg Univ. (Germany). Inst. fuer Experimentalphysik; Stelzer, J. [Michigan State Univ., East Lansing, MI (United States). Dept. of Physics and Astronomy; Collaboration: The Gfitter Group

    2012-09-15

    In view of the discovery of a new boson by the ATLAS and CMS Collaborations at the LHC, we present an update of the global Standard Model (SM) fit to electroweak precision data. Assuming the new particle to be the SM Higgs boson, all fundamental parameters of the SM are known allowing, for the first time, to overconstrain the SM at the electroweak scale and assert its validity. Including the effects of radiative corrections and the experimental and theoretical uncertainties, the global fit exhibits a p-value of 0.07. The mass measurements by ATLAS and CMS agree within 1.3{sigma} with the indirect determination M{sub H}=94{sup +25}{sub -22} GeV. Within the SM the W boson mass and the effective weak mixing angle can be accurately predicted to be M{sub W}=80.359{+-}0.011 GeV and sin{sup 2}{theta}{sup l}{sub eff}=0.23150{+-}0.00010 from the global fit. These results are compatible with, and exceed in precision, the direct measurements. For the indirect determination of the top quark mass we find m{sub t}=175.8{sup +2.7}{sub -2.4} GeV, in agreement with the kinematic and cross-section based measurements.

  18. Optimization through neuron network of the potentiality of Higgs discovery in the CMS detector via H {yields} ZZ{sup *} {yields} 4e{sup {+-}}, and study of the triggering primitives of the electromagnetic calorimeter; Optimisation par reseaux de neurones du potentiel de decouverte du boson de Higgs dans le canal H {yields} ZZ{sup *} {yields} 4e{sup {+-}} sur le detecteur CMS, et etude des primitives de declenchement du calorimetre electromagnetique

    Energy Technology Data Exchange (ETDEWEB)

    Bimbot, St

    2006-10-15

    The first chapter presents the theoretical background on which the Higgs mechanism is based within the framework of the standard model. The second chapter reviews the past and present attempts aiming at the discovery of the Higgs boson. The specific features of the Large Hadron Collider (LHC) and of one of its detector: the CMS (Compact Muon Solenoid) detector are given in the third chapter. The author details the track detector and the ECAL electronic calorimeter that are key components of CMS in the detection of the Higgs boson via the following decay channel: H {yields} ZZ{sup *} {yields} 2e{sup +}2e{sup -} (where Z and Z{sup *} represents the Z{sup O} boson in a real state and in a virtual state respectively). The chapters 4 and 5 are dedicated to the calibration of the ECAL calorimeter via the use of an electron beam and to the triggering system. The data analysis that will lead to the reconstruction of the events detected by CMS is presented in the chapter 6. The last chapter is devoted to the optimization of the extraction of the Higgs boson signal from an abundant background noise. (A.C.)

  19. Topological phases of two-component bosons in species-dependent artificial gauge potentials

    Science.gov (United States)

    Wu, Ying-Hai; Shi, Tao

    2016-08-01

    We study bosonic atoms with two internal states in artificial gauge potentials whose strengths are different for the two components. A series of topological phases for such systems is proposed using the composite fermion theory and the parton construction. It is found in exact diagonalization that some of the proposed states may be realized for simple contact interaction between bosons. The ground states and low-energy excitations of these states are modeled using trial wave functions. The effective field theories for these states are also constructed and reveal some interesting properties.

  20. Fermion-Boson Vertex at Finite Chemical Potential

    Institute of Scientific and Technical Information of China (English)

    ZONG Hong-Shi; FENG Hong-Tao; HOU Feng-Yao; SUN Wei-Min

    2007-01-01

    Based on the Ward-Takahashi identity at finite chemical potential and Lorentz structure analysis, we generalize the Ball-Chiu vertex to the case of nonzero chemical potential and obtain the general form of the fermionboson vertex in QED at finite chemical potential.

  1. Global symplectic potentials on the Witten covariant phase space for bosonic extendons

    CERN Document Server

    Cartas-Fuentevilla, R

    2002-01-01

    It is proved that the projections of the deformation vector field, normal and tangential to the worldsheet manifold swept out by Dirac-Nambu-Goto bosonic extendons propagating in a curved background, play the role of {\\it global} symplectic potentials on the corresponding Witten covariant phase space. It is also proved that the {\\it presymplectic} structure obtained from such potentials by direct exterior derivation, has not components tangent to the action of the relevant diffeomorphisms group of the theory.

  2. Isotropization in Bianchi type-I cosmological model with fermions and bosons interacting via Yukawa potential

    Science.gov (United States)

    Ribas, M. O.; Samojeden, L. L.; Devecchi, F. P.; Kremer, G. M.

    2015-10-01

    In this work we investigate a model for the early Universe in a Bianchi type-I metric, where the sources of the gravitational field are a fermionic and a bosonic field, interacting through a Yukawa potential, following the standard model of elementary particles. It is shown that the fermionic field has a negative pressure, while the boson has a small positive pressure. The fermionic field is the responsible for an accelerated regime at early times, but since the total pressure tends to zero for large times, a transition to a decelerated regime occurs. Here the Yukawa potential answers for the duration of the accelerated regime, since by decreasing the value of its coupling constant the transition accelerated-decelerated occurs in later times. The isotropization which occurs for late times is due to the presence of the fermionic field as one of the sources of the gravitational field.

  3. Isotropization in Bianchi type-I cosmological model with fermions and bosons interacting via Yukawa potential

    CERN Document Server

    Ribas, M O; Devecchi, F P; Kremer, G M

    2015-01-01

    In this work we investigate a model for the early Universe in a Bianchi type-I metric, where the sources of the gravitational field are a fermionic and a bosonic field, interacting through a Yukawa potential, following the standard model of elementary particles. It is shown that the fermionic field has a negative pressure, while the boson has a small positive pressure. The fermionic field is the responsible for an accelerated regime at early times, but since the total pressure tends to zero for large times, a transition to a decelerated regime occurs. Here the Yukawa potential answers for the duration of the accelerated regime, since by decreasing the value of its coupling constant the transition accelerated-decelerated occurs in later times. The isotropization which occurs for late times is due to the presence of the fermionic field as one of the sources of the gravitational field.

  4. Effects of a potential fourth fermion generation on the Higgs boson mass bounds

    CERN Document Server

    Gerhold, P; Kallarackal, J

    2010-01-01

    We study the effect of a potential fourth fermion generation on the upper and lower Higgs boson mass bounds. This investigation is based on the numerical evaluation of a chirally invariant lattice Higgs-Yukawa model emulating the same Higgs-fermion coupling structure as in the Higgs sector of the electroweak Standard Model. In particular, the considered model obeys a Ginsparg-Wilson version of the underlying $SU(2)_L\\times U(1)_Y$ symmetry, being a global symmetry here due to the neglection of gauge fields in this model. We present our results on the modification of the upper and lower Higgs boson mass bounds induced by the presence of a hypothetical very heavy fourth quark doublet. Finally, we compare these findings to the standard scenario of three fermion generations.

  5. Effects of a potential fourth fermion generation on the upper and lower Higgs boson mass bounds

    CERN Document Server

    Gerhold, Philipp; Kallarackal, Jim

    2010-01-01

    We study the effect of a potential fourth fermion generation on the upper and lower Higgs boson mass bounds. This investigation is based on the numerical evaluation of a chirally invariant lattice Higgs-Yukawa model emulating the same Higgs-fermion coupling structure as in the Higgs sector of the electroweak Standard Model. In particular, the considered model obeys a Ginsparg-Wilson version of the underlying ${SU}(2)_L\\times {U}(1)_Y$ symmetry, being a global symmetry here due to the neglection of gauge fields in this model. We present our results on the modification of the upper and lower Higgs boson mass bounds induced by the presence of a hypothetical very heavy fourth quark doublet. Finally, we compare these findings to the standard scenario of three fermion generations.

  6. Assessing the discovery potential of directional detection of Dark Matter

    CERN Document Server

    Billard, J; Santos, D

    2011-01-01

    There is a worldwide effort toward the development of a large TPC (Time Projection Chamber) devoted to directional Dark Matter detection. All current projects are being designed to fulfill a unique goal : identifying weakly interacting massive particle (WIMP) as such by taking advantage of the expected direction dependence of WIMP-induced events toward the constellation Cygnus. However such proof of discovery requires a careful statistical data treatment. In this paper, the discovery potential of forthcoming directional detectors is adressed by using a frequentist approach based on the profile likelihood ratio test statistic. This allows us to estimate the expected significance of a Dark Matter detection. Moreover, using this powerful test statistic, it is possible to propagate astrophysical and experimental uncertainties in the determination of the discovery potential of a given directional detection experiment. This way, we found that a 30 kg.year CF$_4$ directional experiment could reach a 3$\\sigma$ sensit...

  7. A full simulation analysis of the graviscalar discovery potential

    CERN Document Server

    Oye, Ola Kristoffer

    2005-01-01

    We explore the discovery potential for a graviscalar in ATLAS, using full detector simulation. The graviscalar is an extra dimensional supersymmetric partner to the graviton, arising in the bulk in the ADD scenario. The signal from such a particle will be observed as ETmiss accompanied by a high pT jet. The study is based on a previous study [1] performed with ATLFAST.

  8. Academic Training Lecture: Higgs Boson Searches at Hadron Colliders

    CERN Multimedia

    HR Department

    2010-01-01

    Regular Programme 21, 22, 23 & 24 June 2010 from 11:00 to 12:00 - Main Auditorium, Bldg. 500-1-001 Higgs Boson Searches at Hadron Colliders by Dr. Karl Jakobs (University of Freiburg) In these Academic Training lectures, the phenomenology of Higgs bosons and search strategies at hadron colliders are discussed. After a brief introduction on Higgs bosons in the Standard Model and a discussion of present direct and indirect constraints on its mass the status of the theoretical cross section calculations for Higgs boson production at hadron colliders is reviewed. In the following lectures important experimental issues relevant for Higgs boson searches (trigger, measurements of leptons, jets and missing transverse energy) are presented. This is followed by a detailed discussion of the discovery potential for the Standard Model Higgs boson for both the Tevatron and the LHC experiments. In addition, various scenarios beyond the Standard Model, primarily the MSSM, are considered. Finally, the potential and ...

  9. Re-discovery of the SM Higgs boson in diphoton channel at $\\sqrt{s} =$ 13 TeV at CMS in LHC

    CERN Document Server

    Purohit, Arnab

    2017-01-01

    Techniques and results of the re-discovery analysis of standard model Higgs boson decaying to two photons are presented. The analysis is performed on 2016 data at 13TeV centre of mass energy corresponding to an integrated luminosity of 12.9 1/fb taken by the CMS detector in LHC experiment. The central value of mass distribution of the standard model Higgs boson at the Run 1 ATLAS+CMS combined result was m(Higgs) = 125.09 GeV. At this mass point, with the data taken by CMS in 2016, 6.2 $ \\sigma$ significance is expected where the observed significance is 5.6 $ \\sigma$. At 126.0 GeV the maximum significance of 6.1 $ \\sigma$ is observed.

  10. Discovery Potential for SM Higgs with $H \\to ZZ^{(*)} \\to 4l$ at CMS

    CERN Document Server

    Meridiani, P

    2007-01-01

    A prospective analysis is presented for the discovery and properties measurement of the Standard Model Higgs boson in the CMS experiment at the LHC collider. The analysis focuses on the H -> ZZ^ (*) -> 4l + X channel for Higgs boson masses in the range between 120 GeV/c^2 and 600 GeV/c^2. It relies on a full simulation of the detector response and usage of detailed lepton reconstruction tools. Emphasis is put on realistic strategies for the evaluation of experimental systematics and control of physics background processes.

  11. The Higgs Boson in the Standard Model - From LEP to LHC: Expectations, Searches, and Discovery of a Candidate

    CERN Document Server

    Dittmaier, S

    2012-01-01

    The quest for the Higgs boson of the Standard Model, which was a cornerstone in the physics programme at particle colliders operating at the energy frontier for several decades, is the subject of this review. After reviewing the formulation of electroweak symmetry breaking via the Higgs mechanism within the Standard Model, the phenomenology of the Higgs boson at colliders and the theoretical and phenomenological constraints on the Standard Model Higgs sector are discussed. General remarks on experimental searches and the methodology of statistical interpretation are followed by a description of the phenomenology of Higgs-boson production and the corresponding precise predictions. The strategies of the experimental searches and their findings are discussed for the Large Electron Positron Collider (LEP) at CERN, the proton-antiproton collider Tevatron at Fermilab, and the proton-proton Large Hadron Collider (LHC) at CERN. The article concludes with the description of the observation of a Higgs-like boson at the...

  12. Material Discovery and Design with Dynamic Charge Reactive Potentials

    Science.gov (United States)

    Sinnott, Susan

    2015-03-01

    Atomic scale computational simulations of multi-phase systems is increasingly important as our ability to simulate nanometer-sized systems becomes routine. The recently developed charge optimized many body potential (COMB) potentials have significantly enhanced our ability to carry out atomic-scale simulations of heterogeneous material systems. The formalism of this potential combines variable charge electrostatic interactions with a classical analytical bond-order potential. It therefore has the capacity to adaptively model metallic, covalent, ionic, and van der Waals bonding within the same simulation cell and dynamically determine the charges on individual atoms according to the local environment. The utility of the COMB potentials is illustrated for materials design and discovery by exploring the structure, stability, mechanical properties, and thermal properties of intermetallic systems and oxide-metal interfaces. They are also used to address key questions associated with corrosion, thin film growth, and heterogeneous catalysis.

  13. Three-Higgs-doublet models: symmetries, potentials and Higgs boson masses

    Energy Technology Data Exchange (ETDEWEB)

    Keus, Venus [School of Physics and Astronomy, University of Southampton,Southampton, SO17 1BJ (United Kingdom); Department of Physics, Royal Holloway, University of London,Egham Hill, Egham TW20 0EX (United Kingdom); Particle Physics Department, Rutherford Appleton Laboratory,Chilton, Didcot, Oxon OX11 0QX (United Kingdom); King, Stephen F. [School of Physics and Astronomy, University of Southampton,Southampton, SO17 1BJ (United Kingdom); Moretti, Stefano [School of Physics and Astronomy, University of Southampton,Southampton, SO17 1BJ (United Kingdom); Particle Physics Department, Rutherford Appleton Laboratory,Chilton, Didcot, Oxon OX11 0QX (United Kingdom)

    2014-01-13

    We catalogue and study three-Higgs-doublet models in terms of all possible allowed symmetries (continuous and discrete, Abelian and non-Abelian), where such symmetries may be identified as flavour symmetries of quarks and leptons. We analyse the potential in each case, and derive the conditions under which the vacuum alignments (0,0,v), (0,v,v) and (v,v,v) are minima of the potential. For the alignment (0,0,v), relevant for dark matter models, we calculate the corresponding physical Higgs boson mass spectrum. Motivated by supersymmetry, we extend the analysis to the case of three up-type Higgs doublets and three down-type Higgs doublets (six doublets in total). Many of the results are also applicable to flavon models where the three Higgs doublets are replaced by three electroweak singlets.

  14. Vector Boson Fusion Production with rm $H \\to \\gamma\\gamma$

    CERN Document Server

    Dubinin, Mikhail; Ma, Yousi; Newman, Harvey B; Pieri, Marco

    2006-01-01

    A study of CMS discovery potential for an intermediate mass Higgs boson is presented in this note. Results have been obtained for the vector boson fusion (VBF) production mode, rm pp rightarrow rm q q H rightarrow rm q q gamma gamma where the final state includes two high-rapidity jets, during the first years of running at low luminosity. Full detector simulation is used both for the Higgs boson signal and all types of background.

  15. A Jacobian generalization of the pseudo Nambu-Goldstone bosons potential

    CERN Document Server

    Hipólito-Ricaldi, W S

    2015-01-01

    We enlarge the classes of inflaton and quintessence fields by generalizing the pseudo Nambu-Goldstone boson potential by means of elliptic Jacobian functions characterized by a parameter $k$. We use such generalization to implement an inflationary era and a late acceleration of the universe. As an inflationary model the Jacobian generalization leads us to a number of e-foldings and a primordial spectrum of perturbations compatible with the Planck collaboration 2015. As a quintessence model, a study of the evolution of its Equation of State (EoS) and its $w'$-$w$ plane, helps us to classify it as a thawing model. This allows us to consider analytical approximations for the EoS recently discovered for thawing quintessence. By using Union 2.1 Supernova Ia and Hubble parameter $H(z)$ data we determine the range of $k$-values which give rise to viable models for the late acceleration of the universe.

  16. Two-photon decay of the Higgs bosons in a supersymmetric model with a C P -violating potential

    Science.gov (United States)

    Oshimo, Noriyuki

    2016-05-01

    In the supersymmetric standard model which is not minimal, the Higgs potential does not conserve C P symmetry generally. Assuming that there exists an SU(2)-triplet Higgs field, we discuss resultant C P -violating effects on the Higgs bosons. The experimentally observed Higgs boson, which should be C P even in the standard model, could decay into two photons of C P -odd polarization state non-negligibly. For the second lightest Higgs boson, in a sizable region of parameter space, the dominant decay modes are different from those expected by the standard model. The two-photon decay could yield both even and odd C P final states at a ratio of the order of unity.

  17. MSSM Higgs Boson Searches at the LHC: Benchmark Scenarios after the Discovery of a Higgs-like Particle

    Energy Technology Data Exchange (ETDEWEB)

    Carena, M.; Heinemeyer, S.; Stål, O.; Wagner, C.E.M.; Weiglein, G.

    2013-09-01

    A Higgs-like particle with a mass of about 125.5 GeV has been discovered at the LHC. Within the current experimental uncertainties, this new state is compatible with both the predictions for the Standard Model (SM) Higgs boson and with the Higgs sector in the Minimal Supersymmetric Standard Model (MSSM). We propose new low-energy MSSM benchmark scenarios that, over a wide parameter range, are compatible with the mass and production rates of the observed signal. These scenarios also exhibit interesting phenomenology for the MSSM Higgs sector. We propose a slightly updated version of the well-known mh-max scenario, and a modified scenario (mh-mod), where the light CP-even Higgs boson can be interpreted as the LHC signal in large parts of the MA-tan \\beta\\ plane. Furthermore, we define a light stop scenario that leads to a suppression of the lightest CP-even Higgs gluon fusion rate, and a light stau scenario with an enhanced decay rate of h to \\gamma\\gamma\\ at large tan \\beta. We also suggest a \\tau-phobic Higgs scenario in which the lightest Higgs can have suppressed couplings to down-type fermions. We propose to supplement the specified value of the \\mu\\ parameter in some of these scenarios with additional values of both signs. This has a significant impact on the interpretation of searches for the non SM-like MSSM Higgs bosons. We also discuss the sensitivity of the searches to heavy Higgs decays into light charginos and neutralinos, and to decays of the form H to hh. Finally, in addition to all the other scenarios where the lightest CP-even Higgs is interpreted as the LHC signal, we propose a low-MH scenario, where instead the heavy CP-even Higgs boson corresponds to the new state around 125.5 GeV.

  18. Sensitivity and Discovery Potential of the PROSPECT Experiment

    CERN Document Server

    ,

    2015-01-01

    Measurements of the reactor antineutrino flux and spectrum compared to model predictions have revealed an apparent deficit in the interaction rates of reactor antineutrinos and an unexpected spectral deviation. PROSPECT, the Precision Reactor Oscillation Spectrum measurement, is designed to make a precision measurement of the antineutrino spectrum from a research reactor and search for signs of an eV-scale sterile neutrino. PROSPECT will be located at the High Flux Isotope Reactor (HFIR) at Oak Ridge National Laboratory and make use of a Highly Enriched Uranium reactor for a measurement of the pure U-235 antineutrino spectrum. An absolute measurement of this spectrum will constrain reactor models and improve our understanding of the reactor antineutrino spectrum. Additionally, the planned 3-ton lithium-doped liquid scintillator detector is ideally suited to perform a search for sterile neutrinos. This talk will focus on the sensitivity and discovery potential of PROSPECT and the detector design to achieve the...

  19. CERN Library | Tord Ekelöf presents the proceedings of the Nobel Symposium on the Higgs Boson Discovery and Other Recent LHC Results | 12 June

    CERN Multimedia

    2014-01-01

    Thursday, 12 June 2014 at 16:00 in the Library (52-1-052).   The “Nobel Symposium on LHC results” took place at Krusenberg mansion, Uppsala, Sweden on 13-17 May 2013. The aim of the Symposium was to give an overview of the latest experimental and theoretical results pertaining to the LHC programme but also to give an occasion to ponder over the implications of these results in the broader context of the past, present and future evolution of the field of Particle Physics. “Nobel Symposium 154: The Higgs Boson Discovery and Other Recent LHC Results”, ed. by Tord Ekelöf, Physica Scripta T154, IOP, 2013, ISBN 9789789789781. * Coffee will be served from 15:30 * E-proceedings available here.

  20. The W Boson Mass Measurement

    CERN Document Server

    Kotwal, Ashutosh V

    2016-01-01

    The measurement of the W boson mass has been growing in importance as its precision has improved, along with the precision of other electroweak observables and the top quark mass. Over the last decade, the measurement of the W boson mass has been led at hadron colliders. Combined with the precise measurement of the top quark mass at hadron colliders, the W boson mass helped to pin down the mass of the Standard Model Higgs boson through its induced radiative correction on the W boson mass. With the discovery of the Higgs boson and the measurement of its mass, the electroweak sector of the Standard Model is over-constrained. Increasing the precision of the W boson mass probes new physics at the TeV-scale. We summarize an extensive Tevatron (1984–2011) program to measure the W boson mass at the CDF and Dø experiments. We highlight the recent Tevatron measurements and prospects for the final Tevatron measurements.

  1. The W Boson Mass Measurement

    Science.gov (United States)

    Kotwal, Ashutosh V.

    2016-10-01

    The measurement of the W boson mass has been growing in importance as its precision has improved, along with the precision of other electroweak observables and the top quark mass. Over the last decade, the measurement of the W boson mass has been led at hadron colliders. Combined with the precise measurement of the top quark mass at hadron colliders, the W boson mass helped to pin down the mass of the Standard Model Higgs boson through its induced radiative correction on the W boson mass. With the discovery of the Higgs boson and the measurement of its mass, the electroweak sector of the Standard Model is over-constrained. Increasing the precision of the W boson mass probes new physics at the TeV-scale. We summarize an extensive Tevatron (1984-2011) program to measure the W boson mass at the CDF and Dø experiments. We highlight the recent Tevatron measurements and prospects for the final Tevatron measurements.

  2. Symmetry-improved 2PI approach to the Goldstone-boson IR problem of the SM effective potential

    Science.gov (United States)

    Pilaftsis, Apostolos; Teresi, Daniele

    2016-05-01

    The effective potential of the Standard Model (SM), from three loop order and higher, suffers from infrared (IR) divergences arising from quantum effects due to massless would-be Goldstone bosons associated with the longitudinal polarizations of the W± and Z bosons. Such IR pathologies also hinder accurate evaluation of the two-loop threshold corrections to electroweak quantities, such as the vacuum expectation value of the Higgs field. However, these divergences are an artifact of perturbation theory, and therefore need to be consistently resummed in order to obtain an IR-safe effective potential. The so-called Two-Particle-Irreducible (2PI) effective action provides a rigorous framework to consistently perform such resummations, without the need to resort to ad hoc subtractions or running into the risk of over-counting contributions. By considering the recently proposed symmetry-improved 2PI formalism, we address the problem of the Goldstone-boson IR divergences of the SM effective potential in the gaugeless limit of the theory. In the same limit, we evaluate the IR-safe symmetry-improved 2PI effective potential, after taking into account quantum loops of chiral fermions, as well as the renormalization of spurious custodially breaking effects triggered by fermionic Yukawa interactions. Finally, we compare our results with those obtained with other methods presented in the literature.

  3. Symmetry-improved 2PI approach to the Goldstone-boson IR problem of the SM effective potential

    Directory of Open Access Journals (Sweden)

    Apostolos Pilaftsis

    2016-05-01

    Full Text Available The effective potential of the Standard Model (SM, from three loop order and higher, suffers from infrared (IR divergences arising from quantum effects due to massless would-be Goldstone bosons associated with the longitudinal polarizations of the W± and Z bosons. Such IR pathologies also hinder accurate evaluation of the two-loop threshold corrections to electroweak quantities, such as the vacuum expectation value of the Higgs field. However, these divergences are an artifact of perturbation theory, and therefore need to be consistently resummed in order to obtain an IR-safe effective potential. The so-called Two-Particle-Irreducible (2PI effective action provides a rigorous framework to consistently perform such resummations, without the need to resort to ad hoc subtractions or running into the risk of over-counting contributions. By considering the recently proposed symmetry-improved 2PI formalism, we address the problem of the Goldstone-boson IR divergences of the SM effective potential in the gaugeless limit of the theory. In the same limit, we evaluate the IR-safe symmetry-improved 2PI effective potential, after taking into account quantum loops of chiral fermions, as well as the renormalization of spurious custodially breaking effects triggered by fermionic Yukawa interactions. Finally, we compare our results with those obtained with other methods presented in the literature.

  4. Symmetry-Improved 2PI Approach to the Goldstone-Boson IR Problem of the SM Effective Potential

    CERN Document Server

    Pilaftsis, Apostolos

    2015-01-01

    The effective potential of the Standard Model (SM), from three loop order and higher, suffers from infra-red (IR) divergences arising from quantum effects due to massless would-be Goldstone bosons associated with the longitudinal polarizations of the W and Z bosons. Such IR pathologies also hinder accurate evaluation of the two-loop threshold corrections to electroweak quantities, such as the vacuum expectation value of the Higgs field. However, these divergences are an artifact of perturbation theory, and therefore need to be consistently resummed in order to obtain a IR-safe effective potential. The so-called Two-Particle-Irreducible (2PI) effective action provides a rigorous framework to consistently perform such resummations, without the need to resort to ad hoc subtractions or running into the risk of over-counting contributions. By considering the recently proposed symmetry-improved 2PI formalism, we address the problem of the Goldstone-boson IR divergences of the SM effective potential in the gaugeless...

  5. Development of a benchmark parameter scan for Higgs bosons in the NMSSM Model and a study of the sensitivity for H{yields}AA{yields}4{tau} in vector boson fusion with the ATLAS detector

    Energy Technology Data Exchange (ETDEWEB)

    Rottlaender, Iris

    2008-08-15

    An evaluation of the discovery potential for NMSSM Higgs bosons of the ATLAS experiment at the LHC is presented. For this purpose, seven two-dimensional benchmark planes in the six-dimensional parameter space of the NMSSM Higgs sector are defined. These planes include different types of phenomenology for which the discovery of NMSSM Higgs bosons is especially challenging and which are considered typical for the NMSSM. They are subsequently used to give a detailed evaluation of the Higgs boson discovery potential based on Monte Carlo studies from the ATLAS collaboration. Afterwards, the possibility of discovering NMSSM Higgs bosons via the H{sub 1}{yields}A{sub 1}A{sub 1}{yields}4{tau}{yields}4{mu}+8{nu} decay chain and with the vector boson fusion production mode is investigated. A particular emphasis is put on the mass reconstruction from the complex final state. Furthermore, a study of the jet reconstruction performance at the ATLAS experiment which is of crucial relevance for vector boson fusion searches is presented. A good detectability of the so-called tagging jets that originate from the scattered partons in the vector boson fusion process is of critical importance for an early Higgs boson discovery in many models and also within the framework of the NMSSM. (orig.)

  6. North African geology: exploration matrix for potential major hydrocarbon discoveries

    Energy Technology Data Exchange (ETDEWEB)

    Kanes, W.H.; O' Connor, T.E.

    1985-02-01

    Based on results and models presented previously, it is possible to consider an exploration matrix that examines the 5 basic exploration parameters: source, reservoir, timing, structure, and seal. This matrix indicates that even those basins that have had marginal exploration successes, including the Paleozoic megabasin and downfaulted Triassic grabens of Morocco, the Cyrenaican platform of Libya, and the Tunisia-Sicily shelf, have untested plays. The exploration matrix also suggests these high-risk areas could change significantly, if one of the 5 basic matrix parameters is upgraded or if adjustments in political or financial risk are made. The Sirte basin and the Gulf of Suez, 2 of the more intensely explored areas, also present attractive matrix prospects, particularly with deeper Nubian beds or with the very shallow Tertiary sections. The Ghadames basin of Libya and Tunisia shows some potential, but its evaluation responds strongly to stratigraphic and external nongeologic matrix variations based on degree of risk exposure to be assumed. Of greatest risk in the matrix are the very deep Moroccan Paleozoic clastic plays and the Jurassic of Sinai. However, recent discoveries may upgrade these untested frontier areas. Based on the matrix generated by the data presented at a North African Petroleum Geology symposium, significant hydrocarbon accumulations are yet to be found. The remaining questions are: where in the matrix does each individual company wish to place its exploration capital and how much should be the risk exposure.

  7. Higgs boson discovery versus sparticles prediction: Impact on the pMSSM's posterior samples from a Bayesian global fit

    CERN Document Server

    AbdusSalam, Shehu S

    2012-01-01

    The signal strength of the recently discovered Higgs boson-like particle in the diphoton channel seemingly constrains physics beyond the standard model to a severe degree. However, the reported signal strength is prone to possible underestimation of uncertainties. We propose a discriminant that is relatively free of many of the theoretical uncertainties, and use this to gauge the impact on the phenomenological MSSM. A Bayesian global fit to all the pre-LHC data results in posterior distributions for the masses that are neither very restrictive, nor sufficiently prior-independent (except for the Higgs and stop masses). The imposition of the Higgs data, on the other hand, yields interesting and nearly prior-independent constraints. In particular, the existence of some light superpartners is favoured.

  8. Higgs Boson Pizza Day

    CERN Multimedia

    Stefania Pandolfi

    2016-01-01

    CERN celebrated the fourth anniversary of the historical Higgs boson announcement with special pizzas.    400 pizzas were served on Higgs pizza day in Restaurant 1 at CERN to celebrate the fourth anniversary of the announcement of the discovery of the Higgs Boson (Image: Maximilien Brice/ CERN) What do the Higgs boson and a pizza have in common? Pierluigi Paolucci, INFN and CMS collaboration member, together with INFN president Fernando Ferroni found out the answer one day in Naples: the pizza in front of them looked exactly like a Higgs boson event display. A special recipe was then created in collaboration with the chef of the historic “Ettore” pizzeria in the St. Lucia area of Naples, and two pizzas were designed to resemble two Higgs boson decay channel event displays. The “Higgs Boson Pizza Day” was held on Monday, 4 July 2016, on the fourth anniversary of the announcement of the discovery of the Higgs boso...

  9. Bosonic Partition Functions

    CERN Document Server

    Kellerstein, M; Verbaarschot, J J M

    2016-01-01

    The behavior of quenched Dirac spectra of two-dimensional lattice QCD is consistent with spontaneous chiral symmetry breaking which is forbidden according to the Coleman-Mermin-Wagner theorem. One possible resolution of this paradox is that, because of the bosonic determinant in the partially quenched partition function, the conditions of this theorem are violated allowing for spontaneous symmetry breaking in two dimensions or less. This goes back to work by Niedermaier and Seiler on nonamenable symmetries of the hyperbolic spin chain and earlier work by two of the auhtors on bosonic partition functions at nonzero chemical potential. In this talk we discuss chiral symmetry breaking for the bosonic partition function of QCD at nonzero isospin chemical potential and a bosonic random matrix theory at imaginary chemical potential and compare the results with the fermionic counterpart. In both cases the chiral symmetry group of the bosonic partition function is noncompact.

  10. Top Quark Produced Through the Electroweak Force: Discovery Using the Matrix Element Analysis and Search for Heavy Gauge Bosons Using Boosted Decision Trees

    Energy Technology Data Exchange (ETDEWEB)

    Pangilinan, Monica [Brown Univ., Providence, RI (United States)

    2010-05-01

    The top quark produced through the electroweak channel provides a direct measurement of the Vtb element in the CKM matrix which can be viewed as a transition rate of a top quark to a bottom quark. This production channel of top quark is also sensitive to different theories beyond the Standard Model such as heavy charged gauged bosons termed W'. This thesis measures the cross section of the electroweak produced top quark using a technique based on using the matrix elements of the processes under consideration. The technique is applied to 2.3 fb-1 of data from the D0 detector. From a comparison of the matrix element discriminants between data and the signal and background model using Bayesian statistics, we measure the cross section of the top quark produced through the electroweak mechanism σ(p$\\bar{p}$ → tb + X, tqb + X) = 4.30-1.20+0.98 pb. The measured result corresponds to a 4.9σ Gaussian-equivalent significance. By combining this analysis with other analyses based on the Bayesian Neural Network (BNN) and Boosted Decision Tree (BDT) method, the measured cross section is 3.94 ± 0.88 pb with a significance of 5.0σ, resulting in the discovery of electroweak produced top quarks. Using this measured cross section and constraining |Vtb| < 1, the 95% confidence level (C.L.) lower limit is |Vtb| > 0.78. Additionally, a search is made for the production of W' using the same samples from the electroweak produced top quark. An analysis based on the BDT method is used to separate the signal from expected backgrounds. No significant excess is found and 95% C.L. upper limits on the production cross section are set for W' with masses within 600-950 GeV. For four general models of W{prime} boson production using decay channel W' → t$\\bar{p}$, the lower mass limits are the following: M(W'L with SM couplings) > 840 GeV; M(W'R) > 880 GeV or 890 GeV if the

  11. A review of the discovery of SM-like Higgs boson in $H\\rightarrow \\gamma\\gamma$ decay channel with the CMS detector at the LHC

    Indian Academy of Sciences (India)

    SATYAKI BHATTACHARYA; SHILPI JAIN

    2016-09-01

    In this review we have outlined a very brief history of the Higgs boson search and the development of the strategies for searching for the Higgs boson in its diphoton decay channel.We have reviewed the methodology and tools that led to the first observation of the Higgs boson decaying to a pair of photons. We have presented the latest results from the measured properties of the newly found boson.We concentrate for most part on the analysis developed by the CMS experiment, but also present the latest results of the ATLAS experiment along with CMS results.

  12. Search for Higgs boson in beyond standard model scenarios at large hadron collider

    Indian Academy of Sciences (India)

    Kajari Mazumdar; on behalf of the ATLAS and CMS Collaborations

    2007-11-01

    The principal physics motivation of the LHC experiments is to search for the Higgs boson and to probe the physics of TeV energy scale. Potential of discovery for Higgs bosons in various scenarios beyond standard model have been estimated for both CMS and ATLAS experiments through detailed detector simulations. Main results from the recently published studies of CMS collaboration are only included in this write-up.

  13. Phase Diagram of One-Dimensional Bosons in an Array of Local Nonlinear Potentials at Zero Temperature

    Institute of Scientific and Technical Information of China (English)

    SHI Yun-Long; ZHANG Yu-Mei; CHEN Hong; WU Xiang

    2001-01-01

    The Gaussian wave functional method is applied to a boson system with an array of local nonlinear potentials cos [βφ(nR)] to study the phase diagram of its ground state. The stable ground state is determined by the renormalized mass μ which is a function of the parameter γ = β2/4π, the strength of potential α and the potential concentration c. In different cases γ γ2, μ can have different multiplicities, the phase diagram in parameter space is thus depicted. The value γ = γ1 depends on the concentration c, for c → 0, it coincides with that of the single impurity model; while γ2 = 2 coincides with the conclusion of the continuous model.``

  14. Hierarchy in Sampling Gaussian-correlated Bosons

    CERN Document Server

    Huh, Joonsuk

    2016-01-01

    Boson Sampling represents a class of physical processes potentially intractable for classical devices to simulate. The Gaussian extension of Boson Sampling remains a computationally hard problem, where the input state is a product of uncorrelated Gaussian modes. Besides, motivated by molecular spectroscopy, Vibronic Boson Sampling involves operations that can generate Gaussian correlation among different Boson modes. Therefore, Gaussian Boson Sampling is a special case of Vibronic Boson Sampling. However, this does not necessarily mean that Vibronic Boson Sampling is more complex than Gaussian Boson Sampling. Here we develop a hierarchical structure to show how the initial correlation in Vibronic Boson Sampling can be absorbed in Gaussian Boson Sampling with ancillary modes and in a scattershot fashion. Since every Gaussian state is associated with a thermal state, our result implies that every sampling problem in molecular vibronic transitions, at any temperature, can be simulated by Gaussian Boson Sampling ...

  15. Higgs boson pizza

    CERN Multimedia

    Cinzia De Melis

    2016-01-01

    Four years after the historic announcement of the Higgs boson discovery at CERN, a collaboration between INFN and CERN has declared 4 July 2016 as “Higgs Boson Pizza Day”. The idea was born in Naples, by Pierluigi Paolucci and INFN president Fernando Ferroni, who inspired the chef of the historic “Ettore” pizzeria in St. Lucia to create the Higgs boson pizza in time for the opening of a Art&Science exhibition on 15 September 2015 in Naples. The animation shows the culinary creation of a Higgs boson in form of a vegetarian and ham&salami pizza. Ham&Salami: A two asparagus (proton-proton) collision produces a spicy Higgs boson (chorizo) decaying into two high-energy salami (photon) clusters and a lot of charged (sliced ham) and neutral (olive) particles that are detected in the pizza (detector) entirely covered with mozzarella sensors. A two asparagus (proton-proton) collision produces a juicy Higgs boson (cherry tomato) decaying into four high-energy (charged) peppers producing a tasty sign...

  16. Collisional interactions between self-interacting nonrelativistic boson stars: Effective potential analysis and numerical simulations

    Science.gov (United States)

    Cotner, Eric

    2016-09-01

    Scalar particles are a common prediction of many beyond the Standard Model theories. If they are light and cold enough, there is a possibility they may form Bose-Einstein condensates, which will then become gravitationally bound. These boson stars are solitonic solutions to the Einstein-Klein-Gordon equations but may be approximated in the nonrelativistic regime with a coupled Schrödinger-Poisson system. General properties of single soliton states are derived, including the possibility of quartic self-interactions. Binary collisions between two solitons are then studied, and the effects of different mass ratios, relative phases, self-couplings, and separation distances are characterized, leading to an easy conceptual understanding of how these parameters affect the collision outcome in terms of conservation of energy. Applications to dark matter are discussed.

  17. Gravitational Interaction of Higgs Boson and Weak Boson Scattering

    CERN Document Server

    Xianyu, Zhong-Zhi; He, Hong-Jian

    2013-01-01

    With the LHC discovery of a 125GeV Higgs-like particle, we study gravitational interaction of Higgs boson via the unique dimension-4 operator involving Higgs doublet and scalar curvature, \\xi H^\\dag H R, with nonminimal coupling \\xi. This Higgs portal term can be transformed away in Einstein frame and induces gauge-invariant effective interactions in the Higgs sector. We study the weak boson scattering in Einstein frame, and explicitly demonstrate the longitudinal-Goldstone boson equivalence theorem in the presence of \\xi coupling. With these, we derive unitarity bound on the Higgs gravitational coupling \\xi in Einstein frame, which is stronger than that inferred from the LHC Higgs measurements. We further analyze \\xi-dependent weak boson scattering cross sections at TeV scale, and study the LHC probe of \\xi coupling via weak boson scattering experiments.

  18. Searches for the Higgs boson at LHC with the ATLAS Detector

    CERN Document Server

    Kourkoumelis, C

    2009-01-01

    The Higgs boson is the only particle missing to complete the successful description of the elementary ingredients of our world. As of yet, it escapes experimental detection despite the enormous worldwide efforts. The new Large Hadron Collider (LHC) at CERN will provide enough collision energy for its formation, if it exists. The large experiments already installed, are equipped with excellent detector capabilities in order to confirm (or exclude) its existence. Discovery examples for each mass region of the Higgs boson are given using the complete - "as built" - detector simulation and the latest theoretical cross-section calculations, as well as, optimized selection criteria and statistical treatment. Furthermore, the sensitivity for discovery of the Higgs bosons in the framework of the extended SM model, the MSSM, is shortly reviewed. Emphasis is given to the expected discovery potentials from the first years of running.

  19. Study of the physics potential of the FCC-hh machine to measure the coupling of the Higgs boson to b quarks

    CERN Document Server

    Rodríguez, Arturo

    2016-01-01

    The FCC project as well as the Pythia + Delphes analysis within the FCC software are introduced. The ROOT analysis carried out to reconstruct main observables, such the invariant mass of the bb system, transverse mass and momentum of the W boson together with the lepton pT and distribution is explained. The resulting reconstructed invariant mass of the bb system showed a peak near the 125 GeV in correspondence with the Higgs boson. Future steps towards estimating the physics potential of the FCC-hh machine in this channel are discussed.

  20. Neural crest stem cells: discovery, properties and potential for therapy

    Institute of Scientific and Technical Information of China (English)

    Annita Achilleos; Paul A Trainor

    2012-01-01

    Neural crest (NC) cells are a migratory cell population synonymous with vertebrate evolution.They generate a wide variety of cell and tissue types during embryonic and adult development including cartilage and bone,connective tissue,pigment and endocrine cells as well as neurons and glia amongst many others.Such incredible lineage potential combined with a limited capacity for self-renewal,which persists even into adult life,demonstrates that NC cells bear the key hallmarks of stem and progenitor cells.In this review,we describe the identification,characterization and isolation of NC stem and progenitor cells from different tissues in both embryo and adult organisms.We discuss their specific properties and their potential application in cell-based tissue and disease-specific repair.

  1. Search for the Higgs Boson in the H{yields} ZZ{sup (*)}{yields}4{mu} Channel in CMS Using a Multivariate Analysis; Busqueda del Boson de Higgs en el Canal H{yields} ZZ{sup (*)}{yields}4{mu} en CMS Empleando un Metodo de Analisis Multivariado

    Energy Technology Data Exchange (ETDEWEB)

    Alonso Diaz, A.

    2007-12-28

    This note presents a Higgs boson search analysis in the CMS detector of the LHC accelerator (CERN, Geneva, Switzerland) in the H{yields} ZZ{sup (*)}{yields}4{mu} channel, using a multivariate method. This analysis, based in a Higgs boson mass dependent likelihood, constructed from discriminant variables, provides a significant improvement of the Higgs boson discovery potential in a wide mass range with respect to the official analysis published by CMS, based in orthogonal cuts independent of the Higgs boson mass. (Author) 8 refs.

  2. Natural Products Towards the Discovery of Potential Future Antithrombotic Drugs.

    Science.gov (United States)

    Islam, Md Asiful; Alam, Fahmida; Khalil, Md Ibrahim; Sasongko, Teguh Haryo; Gan, Siew Hua

    2016-01-01

    Globally, thrombosis-associated disorders are one of the main contributors to fatalities. Besides genetic influences, there are some acquired and environmental risk factors dominating thrombotic diseases. Although standard regimens have been used for a long time, many side effects still occur which can be life threatening. Therefore, natural products are good alternatives. Although the quest for antithrombotic natural products came to light only since the end of last century, in the last two decades, a considerable number of natural products showing antithrombotic activities (antiplatelet, anticoagulant and fibrinolytic) with no or minimal side effects have been reported. In this review, several natural products used as antithrombotic agents including medicinal plants, vegetables, fruits, spices and edible mushrooms which have been discovered in the last 15 years and their target sites (thrombogenic components, factors and thrombotic pathways) are described. In addition, the side effects, limitations and interactions of standard regimens with natural products are also discussed. The active compounds could serve as potential sources for future research on antithrombotic drug development. As a future direction, more advanced researches (in quest of the target cofactor or component involved in antithrombotic pathways) are warranted for the development of potential natural antithrombotic medications (alone or combined with standard regimens) to ensure maximum safety and efficacy.

  3. Potential for optimizing Higgs boson CP measurement in H to tau tau decay at LHC and ML techniques

    CERN Document Server

    Józefowicz, R; Was, Z

    2016-01-01

    We investigate potential for measuring CP state of the Higgs boson in the H to tau tau$ decay with consecutive tau-lepton decays in channels: tau^+- to rho^+- nu_tau and tau^+- to a1^+- nu_tau combined. Subsequent decays rho^+- to pi^+- pi^0, a1^+- to rho^0 pi^+- and rho^0 to pi^+ pi^- are taken into account. We will explore extensions of the method, where acoplanarity angle for the planes build on the visible decay products, pi^+- pi^0 of tau^+- to pi^pm pi^0 nu_tau, was used. The angle is sensitive to transverse spin correlations, thus to parity. We show, that in the case of the cascade decays of tau to a1 nu, information on the CP state of Higgs can be extracted from the acoplanarity angles as well. Because in the cascade decay a1^+- to rho^0 pi^pm,rho^0 to pi^+ pi^- up to four planes can be defined, up to 16 distinct acoplanarity angles are available for H \\to tau tau to a1^+ a1^- nu nu decays. These acoplanarities carry in part supplementary but also correlated information. It is thus cumbersome to evalu...

  4. Natural NMSSM Higgs bosons

    Energy Technology Data Exchange (ETDEWEB)

    King, Stephen F. [School of Physics and Astronomy, University of Southampton (United Kingdom); Muehlleitner, Margarete; Walz, Kathrin [Institute for Theoretical Physics, Karlsruhe Institute of Technology (Germany); Nevzorov, Roman [Institute for Theoretical and Experimental Physics, Moscow (Russian Federation)

    2013-07-01

    The Higgs sector of the Next-to Minimal Supersymmetric Extension of the Standard Model (NMSSM) features five neutral Higgs bosons. Compared to the MSSM it is extended by one additional complex singlet field. The discovery of a Higgs-like boson at the LHC last summer opens up the exciting possibility to consider the idea that this might actually be one of the NMSSM Higgs bosons. We study the phenomenology of the NMSSM Higgs sector requiring the presence of a CP-even Higgs boson with a mass close to 126 GeV. To this end we perform a parameter scan and investigate the observable Higgs cross sections into the final states γγ, WW, ZZ, bb and ττ. Our focus is on an enhanced rate into γγ. We discuss where such an enhancement can originate from and study the correlations between the different channels. Our scenarios feature light stop masses, which leads to low fine-tuning, and comply nicely with the LHC results.

  5. Higgs Boson Physics at ATLAS

    CERN Document Server

    StDenis, R; The ATLAS collaboration

    2014-01-01

    The discovery of a new boson with the ATLAS detector at the LHC proton-proton collider is confirmed using the full data set collected at centre-of-mass energies of 7 and 8 TeV. The spin and parity properties of the boson are consistent with that of a scalar particle with positive parity. Comparison of the $J^{P}=0^+$ hypothesis to alternatives $J^{P} = 0^-,1^{+},1^-,2^+$ result in exclusion of these other choices at 97.8\\%, 99.97\\%, 99.7\\%, and 99.3\\% CL. The Higgs-boson Mass is $m_H = 125.5 \\pm 0.2 {\\rm (stat.)} ^{+0.5}_{-0.5} {\\rm (syst.)}$ \\GeV. Evidence for production of the Higgs boson by vector boson fusion is obtained in a model-independent approach by comparing the signal strengths $\\mu$ of vector boson fusion and production associated with a vector boson to to that for gluon fusion including associated production of top quark pairs: $\\mu_{\\rm VBF+VH}/\\mu_{\\rm ggF+ttH}= 1.4 ^{+0.4}_{-0.3} \\rm{(stat.)} ^{+0.6}_{-0.4} \\rm{(syst.)}$ which is 3.3 Gaussian standard deviations from zero.

  6. Modified bosonic gas trapped in a generic 3-dim power law potential

    Energy Technology Data Exchange (ETDEWEB)

    Castellanos, E., E-mail: elias@zarm.uni-bremen.de; Laemmerzahl, C., E-mail: claus.laemmerzahl@zarm.uni-bremen.de

    2014-04-04

    We analyze the consequences caused by an anomalous single-particle dispersion relation suggested in several quantum-gravity models, upon the thermodynamics of a Bose–Einstein condensate trapped in a generic 3-dimensional power-law potential. We prove that the condensation temperature is shifted as a consequence of such deformation and show that this fact could be used to provide bounds on the deformation parameters. Additionally, we show that the shift in the condensation temperature, described as a non-trivial function of the number of particles and the trap parameters, could be used as a criterion to analyze the effects caused by a deformed dispersion relation in weakly interacting systems and also in finite size systems.

  7. A new particle is discovered - the Higgs boson ? (english subtitled)

    CERN Multimedia

    2013-01-01

    On the 4th of July 2012, CERN announced the discovery of a new particle, compatible with the Higgs boson. This video (in English and then French at 6:15) describes this important discovery and explains what are the Higgs field and the Higgs boson.

  8. Metagenomics and novel gene discovery: promise and potential for novel therapeutics.

    Science.gov (United States)

    Culligan, Eamonn P; Sleator, Roy D; Marchesi, Julian R; Hill, Colin

    2014-04-01

    Metagenomics provides a means of assessing the total genetic pool of all the microbes in a particular environment, in a culture-independent manner. It has revealed unprecedented diversity in microbial community composition, which is further reflected in the encoded functional diversity of the genomes, a large proportion of which consists of novel genes. Herein, we review both sequence-based and functional metagenomic methods to uncover novel genes and outline some of the associated problems of each type of approach, as well as potential solutions. Furthermore, we discuss the potential for metagenomic biotherapeutic discovery, with a particular focus on the human gut microbiome and finally, we outline how the discovery of novel genes may be used to create bioengineered probiotics.

  9. Chemical analyses of wasp-associated streptomyces bacteria reveal a prolific potential for natural products discovery

    DEFF Research Database (Denmark)

    Poulsen, Michael; Oh, Dong-Chan; Clardy, Jon;

    2011-01-01

    Identifying new sources for small molecule discovery is necessary to help mitigate the continuous emergence of antibiotic-resistance in pathogenic microbes. Recent studies indicate that one potentially rich source of novel natural products is Actinobacterial symbionts associated with social...... phylogenetically diverse and chemically prolific Actinobacteria from solitary wasps suggests that insect-associated Actinobacteria can provide a valuable source of novel natural products of pharmaceutical interest....

  10. CMS standard model Higgs boson results

    Directory of Open Access Journals (Sweden)

    Garcia-Abia Pablo

    2013-11-01

    Full Text Available In July 2012 CMS announced the discovery of a new boson with properties resembling those of the long-sought Higgs boson. The analysis of the proton-proton collision data recorded by the CMS detector at the LHC, corresponding to integrated luminosities of 5.1 fb−1 at √s = 7 TeV and 19.6 fb−1 at √s = 8 TeV, confirm the Higgs-like nature of the new boson, with a signal strength associated with vector bosons and fermions consistent with the expectations for a standard model (SM Higgs boson, and spin-parity clearly favouring the scalar nature of the new boson. In this note I review the updated results of the CMS experiment.

  11. Discovery potential of charged Higgs at LHC in H+- ->tau nu decays

    CERN Document Server

    Tricomi, A

    2001-01-01

    The discovery potential of charged Higgs from pp->tH+- in the H+- -> tau nu decay channel is investigated in CMS and ATLAS. For m_H>m_t, the most relevant channels are H+- -> tb and H+- -> tau nu. Whereas the former has the largest branching ratio it suffers of large irreducible backgrounds, while the latter offers a very clean enviroment when appropriate cuts are used. Making use of the tau polarization effects, in the purely hadronic final states an almost background-free signal is selected. The expected discovery range is evaluated for CMS and ATLAS with 30 fb^-1 each in the low luminosity running conditions and the combined results are presented.

  12. Identification of b-jets and investigation of the discovery potential of a Higgs boson in the $WH --> l \

    CERN Document Server

    Piacquadio, Giacinto

    2010-01-01

    The Standard Model of particle physics describes three of the four known fundamental interactions between the elementary particles: the electromagnetic, weak and strong forces.It provides an extremely accurate description of the electroweak interactions up to the energy scales so far explored in high energy physics experiments. The Large Hadron Collider (LHC), which is presently starting to operate, will provide proton-proton collisions with an unprecedented centre-of-mass energy of $\\sqrt{s} = 14~{\\rm TeV}$ and with instantaneous luminosities of up to $10^{34}~{\\rm cm^{-2}s^{-1}}$, and is therefore ideally suited to explore the TeV energy domain. Two multipurpose experiments, ATLAS and CMS, were built to analyse the collisions. The high instantaneous luminosities achievable at the LHC will result in a significant contamination of the signal processes by additional soft proton-proton collisions, usually known as pile-up interactions. In the course of this thesis several algorithms were developed for the ATLAS...

  13. Higgs Discovery Movie

    CERN Multimedia

    2014-01-01

    The ATLAS & CMS Experiments Celebrate the 2nd Anniversary of the Discovery of the Higgs boson. Here, are some images of the path from LHC startup to Nobel Prize, featuring a musical composition by Roger Zare, performed by the Donald Sinta Quartet, called “LHC”. Happy Discovery Day!

  14. The Higgs boson

    CERN Multimedia

    Brunet, S

    2014-01-01

    ATLAS Higgs poster targeted to general public, explaining the Brout-Englert-Higgs mechanism and why it is important. It also explains the role of the Higgs Boson, how we look for it, the journey of the discovery and what comes after the discovery. Also available in French (http://cds.cern.ch/record/1697501). Don’t hesitate to use it in your institute’s corridors and in your outreach events! The poster is in A0 format. You can click on the image to download the high-quality .pdf version and print it at your favorite printshop. For any questions or comments you can contact atlas-outreach-coordination@cern.ch.

  15. Discovery of the Higgs Boson and a Search for Beyond the Standard Model Physics in ZZ Decays using the CMS Detector at the LHC

    CERN Document Server

    Ross, Ian Ackerman

    2013-01-01

    A study of the $pp \\rightarrow ZZ \\rightarrow \\ell\\ell\\ell\\ell$ final state is conducted using 19.6$fb^{-1}$ of 8 TeV proton-proton collisions at the LHC using the CMS detector. The Standard Model $pp \\rightarrow ZZ$ production cross section is measured to be $\\sigma(pp\\rightarrow ZZ) = 7.7^{+0.5}_{-0.5} \\textrm(stat.) ^{+0.6}_{-0.5} \\textrm{(sys.)} \\pm 0.3 \\textrm{(lumi)}~\\textrm{pb} $. Evidence of a new Higgs-like boson is observed with a significance of $6.1 \\sigma$ at 126~GeV. 95% confidence level upper limits are set on the neutral anomalous triple gauge\

  16. Chemical analyses of wasp-associated streptomyces bacteria reveal a prolific potential for natural products discovery

    DEFF Research Database (Denmark)

    Poulsen, Michael; Oh, Dong-Chan; Clardy, Jon;

    2011-01-01

    Identifying new sources for small molecule discovery is necessary to help mitigate the continuous emergence of antibiotic-resistance in pathogenic microbes. Recent studies indicate that one potentially rich source of novel natural products is Actinobacterial symbionts associated with social...... of these isolates identified 11 distinct and structurally diverse secondary metabolites, including a novel polyunsaturated and polyoxygenated macrocyclic lactam, which we name sceliphrolactam. By pairing the 15 Streptomyces strains against a collection of fungi and bacteria, we document their antifungal...... and antibacterial activity. The prevalence and anti-microbial properties of Actinobacteria associated with these two solitary wasp species suggest the potential role of these Streptomyces as antibiotic-producing symbionts, potentially helping defend their wasp hosts from pathogenic microbes. Finding...

  17. Latest results on anomalous gauge boson couplings with the ATLAS experiment

    CERN Document Server

    Schnoor, Ulrike; The ATLAS collaboration

    2015-01-01

    Contributions from new physics in the electroweak sector can be described in a model-independent way by anomalous gauge boson couplings in the framework of an effective field theory. Measurements of these parameters allow for the exclusion or discovery of contributions beyond the Standard Model. Experimentally, electroweak triple gauge boson couplings have been accessible in di-boson production at the LHC and at previous colliders. More recently, the first measurements of triple gauge boson couplings in vector boson production through vector boson fusion have been achieved. The first observations of vector boson scattering and triple boson production processes have been made recently at the LHC, giving the possibility to measure quartic gauge boson interactions of electroweak vector bosons. These proceedings describe measurements at the ATLAS detector at the LHC in various channels which allow to set limits on anomalous triple and quartic gauge boson couplings. All measurements show good agreement with the pr...

  18. Two-boson composites

    DEFF Research Database (Denmark)

    Tichy, Malte C.; Bouvrier, P. Alexander; Mølmer, Klaus

    2013-01-01

    Composite bosons made of two bosonic constituents exhibit deviations from ideal bosonic behavior due to their substructure. This deviation is reflected by the normalization ratio of the quantum state of N composites. We find a set of saturable, efficiently evaluable bounds for this indicator, which...... quantifies the bosonic behavior of composites via the entanglement of their constituents. We predict an abrupt transition between ordinary and exaggerated bosonic behavior in a condensate of two-boson composites....

  19. Cancer Chemoprevention Effects of Ginger and its Active Constituents: Potential for New Drug Discovery.

    Science.gov (United States)

    Wang, Chong-Zhi; Qi, Lian-Wen; Yuan, Chun-Su

    2015-01-01

    Ginger is a commonly used spice and herbal medicine worldwide. Besides its extensive use as a condiment, ginger has been used in traditional Chinese medicine for the management of various medical conditions. In recent years, ginger has received wide attention due to its observed antiemetic and anticancer activities. This paper reviews the potential role of ginger and its active constituents in cancer chemoprevention. The phytochemistry, bioactivity, and molecular targets of ginger constituents, especially 6-shogaol, are discussed. The content of 6-shogaol is very low in fresh ginger, but significantly higher after steaming. With reported anti-cancer activities, 6-shogaol can be served as a lead compound for new drug discovery. The lead compound derivative synthesis, bioactivity evaluation, and computational docking provide a promising opportunity to identify novel anticancer compounds originating from ginger.

  20. Augmenting Collider Searches and Enhancing Discovery Potentials through Stochastic Jet Grooming

    CERN Document Server

    Roy, Tuhin S

    2016-01-01

    The jet Trimming procedure has been demonstrated to greatly improve event reconstruction in hadron collisions, by mitigating contamination due initial state radiation, multiple interactions, and event pileup. Meanwhile, Qjets -- a nondeterministic approach to tree-based jet substructure has been shown to be a powerful technique in decreasing random statistical fluctuations, yielding significant effective luminosity improvements. This manifests through an improvement in the significance $S/\\delta B$, relative to conventional methods. Qjets also provide novel observables in many cases, like mass-volatility, that could be used to further discriminate between signal and background events. The statistical robustness and volatility observables, for tagging, are obtained simultaneously. We explore here a combination of the two techniques, and demonstrate that significant enhancements in discovery potentials may be obtained in non-trivial ways. We will illustrate this by considering a diboson resonance analysis as a ...

  1. Fly pupae and puparia as potential contaminants of forensic entomology samples from sites of body discovery.

    Science.gov (United States)

    Archer, M S; Elgar, M A; Briggs, C A; Ranson, D L

    2006-11-01

    Fly pupae and puparia may contaminate forensic entomology samples at death scenes if they have originated not from human remains but from animal carcasses or other decomposing organic material. These contaminants may erroneously lengthen post-mortem interval estimates if no pupae or puparia are genuinely associated with the body. Three forensic entomology case studies are presented, in which contamination either occurred or was suspected. In the first case, blow fly puparia collected near the body were detected as contaminants because the species was inactive both when the body was found and when the deceased was last sighted reliably. The second case illustrates that contamination may be suspected at particularly squalid death scenes because of the likely presence of carcasses or organic material. The third case involves the presence at the body discovery site of numerous potentially contaminating animal carcasses. Soil samples were taken along transects to show that pupae and puparia were clustered around their probable sources.

  2. Reconstruction of Higgs bosons in the di-tau channel via 3-prong decay

    Energy Technology Data Exchange (ETDEWEB)

    Gripaios, Ben; Webber, Bryan [Cambridge Univ. (United Kingdom). Cavendish Lab.; Nagao, Keiko [KEK Theory Center, Tsukuba (Japan); Nojiri, Mihoko [KEK Theory Center, Tsukuba (Japan); The Graduate Univ. for Advanced Studies (Sokendai) IPNS, KEK, Tsukuba (Japan); Kavli Institute of the Physics and Mathematics of the Universe (Kavli IPMU), Chiba (Japan); Sakurai, Kazuki [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany)

    2012-10-15

    We propose a method for reconstructing the mass of a particle, such as the Higgs boson, decaying into a pair of {tau} leptons, of which one subsequently undergoes a 3-prong decay. The kinematics is solved using information from the visible decay products, the missing transverse momentum, and the 3-prong {tau} decay vertex, with the detector resolution taken into account using a likelihood method. The method is shown to give good discrimination between a 125 GeV Higgs boson signal and the dominant backgrounds, such as Z{sup 0} decays to {tau}{tau} and W{sup {+-}} plus jets production. As a result, we find an improvement, compared to existing methods for this channel, in the discovery potential, as well as in measurements of the Higgs boson mass and production cross section times branching ratio.

  3. Effects of pairing potential scattering on Fourier-transformed inelastic tunneling spectra of high-Tc cuprate superconductors with bosonic modes.

    Science.gov (United States)

    Zhu, Jian-Xin; McElroy, K; Lee, J; Devereaux, T P; Si, Qimiao; Davis, J C; Balatsky, A V

    2006-10-27

    Recent scanning tunneling microscopy (STM) experimentally observed strong gap inhomogeneity in Bi2Sr2CaCu2O(8+delta) (BSCCO). We argue that disorder in the pair potential underlies the gap inhomogeneity, and investigate its role in the Fourier-transformed inelastic tunneling spectra as revealed in the STM. We find that the random pair potential induces unique q-space patterns in the local density of states (LDOS) of a d-wave superconductor. We consider the effects of electron coupling to various bosonic modes and find the pattern of LDOS modulation due to coupling to the B(1g) phonon mode to be consistent with the one observed in the inelastic electron tunnneling STM experiment in BSCCO. These results suggest strong electron-lattice coupling as an essential part of the superconducting state in high-Tc materials.

  4. Collisional interactions between self-interacting non-relativistic boson stars: effective potential analysis and numerical simulations

    CERN Document Server

    Cotner, Eric

    2016-01-01

    Scalar particles are a common prediction of many beyond the Standard Model theories. If they are light and cold enough, there is a possibility they may form Bose-Einstein condensates, which will then become gravitationally bound. These boson stars are solitonic solutions to the Einstein-Klein-Gordon equations, but may be approximated in the non-relativistic regime with a coupled Schr\\"odinger-Poisson system. General properties of single soliton states are derived, including the possibility of quartic self-interactions. Binary collisions between two solitons are then studied, and the effects of different mass ratios, relative phases, self-couplings, and separation distances are characterized, leading to an easy conceptual understanding of how these parameters affect the collision outcome in terms of conservation of energy. Applications to dark matter are discussed.

  5. Higgs Boson Production and Weak Boson Structure

    OpenAIRE

    1995-01-01

    The influence of the QCD structure of the weak bosons on the Higgs boson production in $e$-$p$ scattering is studied. The energy and Higgs boson mass dependence of the cross-section, following from the new contributions, is calculated.

  6. Chemical analyses of wasp-associated streptomyces bacteria reveal a prolific potential for natural products discovery.

    Directory of Open Access Journals (Sweden)

    Michael Poulsen

    Full Text Available Identifying new sources for small molecule discovery is necessary to help mitigate the continuous emergence of antibiotic-resistance in pathogenic microbes. Recent studies indicate that one potentially rich source of novel natural products is Actinobacterial symbionts associated with social and solitary Hymenoptera. Here we test this possibility by examining two species of solitary mud dauber wasps, Sceliphron caementarium and Chalybion californicum. We performed enrichment isolations from 33 wasps and obtained more than 200 isolates of Streptomyces Actinobacteria. Chemical analyses of 15 of these isolates identified 11 distinct and structurally diverse secondary metabolites, including a novel polyunsaturated and polyoxygenated macrocyclic lactam, which we name sceliphrolactam. By pairing the 15 Streptomyces strains against a collection of fungi and bacteria, we document their antifungal and antibacterial activity. The prevalence and anti-microbial properties of Actinobacteria associated with these two solitary wasp species suggest the potential role of these Streptomyces as antibiotic-producing symbionts, potentially helping defend their wasp hosts from pathogenic microbes. Finding phylogenetically diverse and chemically prolific Actinobacteria from solitary wasps suggests that insect-associated Actinobacteria can provide a valuable source of novel natural products of pharmaceutical interest.

  7. Mass Generation, the Cosmological Constant Problem, Conformal Symmetry, and the Higgs Boson

    CERN Document Server

    Mannheim, Philip D

    2016-01-01

    In 2013 the Nobel Prize in Physics was awarded to Francois Englert and Peter Higgs for their work in 1964 along with the late Robert Brout on the mass generation mechanism (the Higgs mechanism) in local gauge theories. This mechanism requires the existence of a massive scalar particle, the Higgs boson, and in 2012 the Higgs boson was finally discovered at the Large Hadron Collider after being sought for almost half a century. In this article we review the work that led to the discovery of the Higgs boson and discuss its implications. We approach the topic from the perspective of a dynamically generated Higgs boson that is a fermion-antifermion bound state rather than an elementary field that appears in an input Lagrangian. In particular, we emphasize the connection with the Barden-Cooper-Schrieffer theory of superconductivity. We identify the double-well Higgs potential not as a fundamental potential but as a mean-field effective Lagrangian with a dynamical Higgs boson being generated through a residual inter...

  8. Recent developments in L-asparaginase discovery and its potential as anticancer agent.

    Science.gov (United States)

    Shrivastava, Abhinav; Khan, Abdul Arif; Khurshid, Mohsin; Kalam, Mohd Abul; Jain, Sudhir K; Singhal, Pradeep K

    2016-04-01

    L-Asparaginase (EC3.5.1.1) is an enzyme, which is used for treatment of acute lymphoblastic leukaemia (ALL) and other related blood cancers from a long time. This enzyme selectively hydrolyzes the extracellular amino acid L-asparagine into L-aspartate and ammonia, leading to nutritional deficiencies, protein synthesis inhibition, and ultimately death of lymphoblastic cells by apoptosis. Currently, bacterial asparaginases are used for treatment purpose but offers scepticism due to a number of toxicities, including thrombosis, pancreatitis, hyperglycemia, and hepatotoxicity. Resistance towards bacterial asparaginase is another major disadvantage during cancer management. This situation attracted attention of researchers towards alternative sources of L-asparaginase, including plants and fungi. Present article discusses about potential of L-asparaginase as an anticancer agent, its mechanism of action, and adverse effects related to current asparaginase formulations. This article also provides an outlook for recent developments in L-asparaginase discovery from alternative sources and their potential as a less toxic alternative to current formulations.

  9. Development and exploration of potential routes of discovery of new superconductors

    Energy Technology Data Exchange (ETDEWEB)

    Lin, Xiao [Iowa State Univ., Ames, IA (United States)

    2013-01-01

    This thesis summarizes our efforts to develop and explore potential routes for the discovery of new superconductors. The development of viable solutions for sulfur-bearing compounds is presented. It also provides the details of searching for quantum critical points (QCPs) and possible superconductors by suppressing ferromagnetic states via chemical substitution and the application of pressure. The ferromagnetism in La(VxCr1-x)Ge3 was successfully suppressed by pressure, and, in addition, a potential QCP at ambient pressure was discovered for x = 0.16. On the other hand, the La(VxCr1-x)Sb3 series is likely to evolve into new magnetic state with V-substitution with the Cr-based magnetism appearing to be more local-moment like than for the case of LaCrGe3. We also performed detailed characterization on BaSn5 superconductor, giving further understanding of its superconducting state, and on R3Ni2-xSn7 and RNi1-xBi2±y series putting to rest spurious claims of superconductivity.

  10. Virtual target screening to rapidly identify potential protein targets of natural products in drug discovery

    Directory of Open Access Journals (Sweden)

    Yuri Pevzner

    2014-05-01

    Full Text Available Inherent biological viability and diversity of natural products make them a potentially rich source for new therapeutics. However, identification of bioactive compounds with desired therapeutic effects and identification of their protein targets is a laborious, expensive process. Extracts from organism samples may show desired activity in phenotypic assays but specific bioactive compounds must be isolated through further separation methods and protein targets must be identified by more specific phenotypic and in vitro experimental assays. Still, questions remain as to whether all relevant protein targets for a compound have been identified. The desire is to understand breadth of purposing for the compound to maximize its use and intellectual property, and to avoid further development of compounds with insurmountable adverse effects. Previously we developed a Virtual Target Screening system that computationally screens one or more compounds against a collection of virtual protein structures. By scoring each compound-protein interaction, we can compare against averaged scores of synthetic drug-like compounds to determine if a particular protein would be a potential target of a compound of interest. Here we provide examples of natural products screened through our system as we assess advantages and shortcomings of our current system in regards to natural product drug discovery.

  11. Microbial P450 enzymes in bioremediation and drug discovery: Emerging potentials and challenges.

    Science.gov (United States)

    Bhattacharya, Sukanta S; Yadav, Jagjit S

    2016-11-21

    Cytochrome P450 enzymes are a structurally conserved but functionally diverse group of heme-containing mixed function oxidases found across both prokaryotic and eukaryotic forms of the microbial world. Microbial P450s are known to perform diverse functions ranging from the synthesis of cell wall components to xenobiotic/drug metabolism to biodegradation of environmental chemicals. Conventionally, many microbial systems have been reported to mimic mammalian P450-like activation of drugs and were proposed as the in-vitro models of mammalian drug metabolism. Recent reports suggest that native or engineered forms of specific microbial P450s from these and other microbial systems could be employed for desired specific biotransformation reactions toward natural and synthetic (drug) compounds underscoring their emerging potential in drug improvement and discovery. On the other hand, microorganisms particularly fungi and actinomycetes have been shown to possess catabolic P450s with unusual potential to degrade toxic environmental chemicals including persistent organic pollutants (POPs). Wood-rotting basidiomycete fungi in particular have revealed the presence of exceptionally large P450 repertoire (P450ome) in their genomes, majority of which are however orphan (with no known function). Our pre- and post-genomic studies have led to functional characterization of several fungal P450s inducible in response to exposure to several environmental toxicants and their potential in bioremediation of these chemicals. This review is an attempt to summarize the post-genomic unveiling of this versatile enzyme superfamily in microbial systems and investigation of their potential to synthesize new drugs and degrade persistent pollutants, among other biotechnological applications.

  12. Evidence of Higgs Boson Production through Vector Boson Fusion

    CERN Document Server

    AUTHOR|(INSPIRE)INSPIRE-00333580

    The discovery of the Higgs boson in 2012 provided confirmation of the proposed mechanism for preserving the electroweak $SU(2) \\times U(1)$ gauge symmetry of the Standard Model of particle physics. It also heralded in a new era of precision Higgs physics. This thesis presents a measurement of the rate at which the Higgs boson is produced by vector boson fusion in the \\wwlnln decay channel. With gauge boson couplings in both the production and decay vertices, a VBF measurement in this channel is a powerful probe of the $VVH$ vertex strength. Using $4.5$~fb$^{-1}$ and $20.3$~fb$^{-1}$ of $pp$ collision data collected at respective center-of-mass energies of 7 and $8 \\tev$ in the ATLAS detector, measurements of the statistical significance and the signal strength are carried out in the Higgs mass range $100 \\leq m_H \\leq 200 \\gev$. These measurements are enhanced with a boosted decision tree that exploits the correlations between eight kinematic inputs in order to separate signal and background processes. At the...

  13. Bosonic Coherent Motions in the Universe

    Directory of Open Access Journals (Sweden)

    Jihn E. Kim

    2014-10-01

    Full Text Available We review the role of fundamental spin-0 bosons as bosonic coherent motion (BCM in the Universe. The fundamental spin-0 bosons have the potential to account for the baryon number generation, cold dark matter (CDM via BCM, inflation, and dark energy. Among these, we pay particular attention to the CDM possibility because it can be experimentally tested with the current experimental techniques. We also comment on the panoply of the other roles of spin-0 bosons--such as those for cosmic accelerations at early and late times.

  14. Potential for optimizing the Higgs boson C P measurement in H →τ τ decays at the LHC including machine learning techniques

    Science.gov (United States)

    Józefowicz, R.; Richter-Was, E.; Was, Z.

    2016-11-01

    We investigate the potential for measuring the C P state of the Higgs boson in H →τ τ decays with consecutive τ -lepton decays in the channels: τ±→ρ±ντ and τ±→a1±ντ combined. Subsequent decays ρ±→π±π0, a1±→ρ0π± and ρ0→π+π- are taken into account. We will explore extensions of the method, where the acoplanarity angle for the planes build on the visible decay products, π±π0 of τ±→π±π0ντ, was used. The angle is sensitive to transverse spin correlations, thus to parity. We show that in the case of the cascade decays of τ →a1ν , information on the C P state of Higgs can be extracted from the acoplanarity angles as well. Because in the cascade decay a1±→ρ0π± , ρ0→π+π- up to four planes can be defined, up to 16 distinct acoplanarity angles are available for H →τ τ →a1+a1-ν ν decays. These acoplanarities carry in part supplementary but also correlated information. It is thus cumbersome to evaluate an overall sensitivity. We investigate the sensitivity potential of such analysis, by developing and applying machine learning techniques. We quantify possible improvements when multidimensional phase space of outgoing decay products directions is used, instead of one-dimensional projections i.e. the acoplanarity angles. We do not take into account ambiguities resulting from detector uncertainties or background contamination; we concentrate on the usefulness of machine learning methods and τ →3 π ν decays for Higgs boson parity measurement.

  15. Prospects for the study of vector boson scattering in same sign WW and WZ interactions at the HL-LHC with the upgraded CMS detector

    CERN Document Server

    CMS Collaboration

    2016-01-01

    Studies of the $pp \\rightarrow \\mathrm{\\mathrm{W}^{\\pm}Z} jj$ and $pp \\rightarrow\\mathrm{\\mathrm{W}^{\\pm}\\mathrm{W}^{\\pm}} jj$ vector boson scattering processes in 14 TeV pp collisions using the planned upgrades of the CMS detector are presented. These studies include assessments on the expected precision in measuring the electroweak cross sections, the discovery potential for observing longitudinal vector boson scattering and limits on partial unitarization scenarios between vector boson scattering and the Higgs boson. Beyond the standard model sensitivity is probed in the framework of the effective field theory by extracting expected limits on quartic gauge couplings for $\\mathrm{\\mathrm{W}^{\\pm}\\mathrm{W}^{\\pm}}$ scattering. All results are presented with a luminosity of $3~\\mathrm{ab}^{-1}$ and comparisons with the non upgraded CMS detector including its aging due to radiation are performed.

  16. Acquiring a taste for the Higgs boson

    CERN Multimedia

    Caroline Duc

    2012-01-01

    Before CERN's scientists had even announced the discovery of the Higgs boson, others were already attributing some interesting characteristics to it: flavoursome, sparkling and liquid...   The artisan brewery Hopfenstark in Quebec launched its new "Higgs boson" beer in November 2010. Ever since, it has been intriguing enthusiasts with its unique taste explosion. The boson was a source of inspiration for brewer Frédéric Cormier, the Hopfenstark brewery's owner, who is a big fan of science programmes. "I returned from a trip to Europe in 2010 with the idea for a new beer that would be unlike any other," he explains. "I was always reading and hearing about CERN's particle accelerator in the media, so I did some research on the famous Higgs boson and decided to give my new creation the same name." For Frédéric Cormier, it's important that the names of his beers refle...

  17. Cracking the particle code of the universe the hunt for the Higgs boson

    CERN Document Server

    Moffat, John W

    2014-01-01

    Among the current books that celebrate the discovery of the Higgs boson, Cracking the Particle Code of the Universe is a rare objective treatment of the subject. The book is an insider's behind-the-scenes look at the arcane, fascinating world of theoretical and experimental particle physics leading up to the recent discovery of a new boson. If the new boson is indeed the Higgs particle, its discovery represents an important milestone in the history of particle physics. However, despite the pressure to award Nobel Prizes to physicists associated with the Higgs boson, John Moffat argues that the

  18. Higgs Boson Masses in NMSSM with Spontaneous CP-violation

    OpenAIRE

    1996-01-01

    The Higgs boson mass problem is considered in the next-to-minimal supersymmetric standard model for the case of the spontaneous CP violation. The renormalization group equations for the gauge, Yukawa and scalar coupling constants, the effective Higgs potential and lower experimental bounds on Higgs boson and chargino masses are analyzed. The restrictions on the Higgs boson masses are found.

  19. LHC Higgs boson results involving fermions

    CERN Document Server

    Chen, X; The ATLAS collaboration

    2013-01-01

    Following the discovery of a Higgs-like particle in the bosonic decay modes, the fermionic decay modes need to be seen to prove this particle is a Standard Model (SM) Higgs. In this presentation, an overview of the recent Higgs search results in the fermionic decays of $\\tau\\tau$, $b\\bar{b}$, $\\mu\\mu$ and $\\tau\

  20. A Scientometric Prediction of the Discovery of the First Potentially Habitable Planet with a Mass Similar to Earth

    CERN Document Server

    Arbesman, Samuel

    2010-01-01

    The search for a habitable extrasolar planet has long interested scientists, but only recently have the tools become available to search for such planets. In the past decades, the number of known extrasolar planets has ballooned into the hundreds, and with it the expectation that the discovery of the first Earth-like extrasolar planet is not far off. Here we develop a novel metric of habitability for discovered planets, and use this to arrive at a prediction for when the first habitable planet will be discovered. Using a bootstrap analysis of currently discovered exoplanets, we predict the discovery of the first Earth-like planet to be announced in the first half of 2011, with the likeliest date being early May 2011. Our predictions, using only the properties of previously discovered exoplanets, accord well with external estimates for the discovery of the first potentially habitable extrasolar planet, and highlights the the usefulness of predictive scientometric techniques to understand the pace of scientific...

  1. The Higgs Boson.

    Science.gov (United States)

    Veltman, Martinus J. G.

    1986-01-01

    Reports recent findings related to the particle Higgs boson and examines its possible contribution to the standard mode of elementary processes. Critically explores the strengths and uncertainties of the Higgs boson and proposed Higgs field. (ML)

  2. Working Group Report: Higgs Boson

    Energy Technology Data Exchange (ETDEWEB)

    Dawson, Sally; Gritsan, Andrei; Logan, Heather; Qian, Jianming; Tully, Chris; Van Kooten, Rick [et al.

    2013-10-30

    This report summarizes the work of the Energy Frontier Higgs Boson working group of the 2013 Community Summer Study (Snowmass). We identify the key elements of a precision Higgs physics program and document the physics potential of future experimental facilities as elucidated during the Snowmass study. We study Higgs couplings to gauge boson and fermion pairs, double Higgs production for the Higgs self-coupling, its quantum numbers and $CP$-mixing in Higgs couplings, the Higgs mass and total width, and prospects for direct searches for additional Higgs bosons in extensions of the Standard Model. Our report includes projections of measurement capabilities from detailed studies of the Compact Linear Collider (CLIC), a Gamma-Gamma Collider, the International Linear Collider (ILC), the Large Hadron Collider High-Luminosity Upgrade (HL-LHC), Very Large Hadron Colliders up to 100 TeV (VLHC), a Muon Collider, and a Triple-Large Electron Positron Collider (TLEP).

  3. Spherical Boson Stars as Black Hole mimickers

    CERN Document Server

    Guzman, F S; 10.1103/PhysRevD.80.084023

    2010-01-01

    We present spherically symmetric boson stars as black hole mimickers based on the power spectrum of a simple accretion disk model. The free parameters of the boson star are the mass of the boson and the fourth order self-interaction coefficient in the scalar field potential. We show that even if the mass of the boson is the only free parameter it is possible to find a configuration that mimics the power spectrum of the disk due to a black hole of the same mass. We also show that for each value of the self-interaction a single boson star configuration can mimic a black hole at very different astrophysical scales in terms of the mass of the object and the accretion rate. In order to show that it is possible to distinguish one of our mimickers from a black hole we also study the deflection of light.

  4. Bosonization and quantum hydrodynamics

    Indian Academy of Sciences (India)

    Girish S Setlur

    2006-03-01

    It is shown that it is possible to bosonize fermions in any number of dimensions using the hydrodynamic variables, namely the velocity potential and density. The slow part of the Fermi field is defined irrespective of dimensionality and the commutators of this field with currents and densities are exponentiated using the velocity potential as conjugate to the density. An action in terms of these canonical bosonic variables is proposed that reproduces the correct current and density correlations. This formalism in one dimension is shown to be equivalent to the Tomonaga-Luttinger approach as it leads to the same propagator and exponents. We compute the one-particle properties of a spinless homogeneous Fermi system in two spatial dimensions with long-range gauge interactions and highlight the metal-insulator transition in the system. A general formula for the generating function of density correlations is derived that is valid beyond the random phase approximation. Finally, we write down a formula for the annihilation operator in momentum space directly in terms of number conserving products of Fermi fields.

  5. A scientometric prediction of the discovery of the first potentially habitable planet with a mass similar to Earth.

    Directory of Open Access Journals (Sweden)

    Samuel Arbesman

    Full Text Available BACKGROUND: The search for a habitable extrasolar planet has long interested scientists, but only recently have the tools become available to search for such planets. In the past decades, the number of known extrasolar planets has ballooned into the hundreds, and with it, the expectation that the discovery of the first Earth-like extrasolar planet is not far off. METHODOLOGY/PRINCIPAL FINDINGS: Here, we develop a novel metric of habitability for discovered planets and use this to arrive at a prediction for when the first habitable planet will be discovered. Using a bootstrap analysis of currently discovered exoplanets, we predict the discovery of the first Earth-like planet to be announced in the first half of 2011, with the likeliest date being early May 2011. CONCLUSIONS/SIGNIFICANCE: Our predictions, using only the properties of previously discovered exoplanets, accord well with external estimates for the discovery of the first potentially habitable extrasolar planet and highlight the the usefulness of predictive scientometric techniques to understand the pace of scientific discovery in many fields.

  6. Potential insight for drug discovery from high fidelity receptor-mediated transduction mechanisms in insects

    Science.gov (United States)

    Raffa, Robert B.; Raffa, Kenneth F.

    2011-01-01

    Introduction There is a pervasive and growing concern about the small number of new pharmaceutical agents. There are many proposed explanations for this trend that do not involve the drug-discovery process per se, but the discovery process itself has also come under scrutiny. If the current paradigms are indeed not working, where are novel ideas to come from? Perhaps it is time to look to novel sources. Areas covered The receptor-signaling and 2nd-messenger transduction processes present in insects are quite similar to those in mammals (involving G proteins, ion channels, etc.). However, a review of these systems reveals an unprecedented degree of high potency and receptor selectivity to an extent greater than that modeled in most current drug-discovery approaches. Expert opinion A better understanding of insect receptor pharmacology could stimulate novel theoretical and practical ideas in mammalian pharmacology (drug discovery) and, conversely, the application of pharmacology and medicinal chemistry principles could stimulate novel advances in entomology (safer and more targeted control of pest species). PMID:21984882

  7. INSECTS AND THEIR CHEMICAL WEAPONRY: GREAT POTENTIAL AND NEW DISCOVERIES FROM THE ORDER PHASMATODEA

    Science.gov (United States)

    With over 1,000,000 species of insects known, Class Insecta (Phyllum Arthropoda), the largest and most diverse group of organisms, is one of the least explored in natural product drug discovery (Dossey, A. T., Nat. Prod Rep. 2010, 27, 1737–1757). Over the past five our research stick insect chemical...

  8. Searches for BSM Higgs Bosons with ATLAS

    CERN Document Server

    Navarro, Gabriela; The ATLAS collaboration

    2015-01-01

    The discovery of a Higgs-like boson with a mass of about 125GeV has prompted the question of whether or not this particle is part of a much larger and more complex Higgs sector than that envisioned in the Standard Model. In this talk, the current results from the ATLAS Experiment regarding Beyond-the-Standard Model (BSM) Higgs hypothesis tests are outlined. Searches for additional Higgs bosons are presented and interpreted in well-motivated BSM Higgs frameworks, such as two-Higgs-doublet Models and the Minimal Supersymmetric Standard Model.

  9. Facile diverted synthesis of pyrrolidinyl triazoles using organotrifluoroborate: discovery of potential mPTP blockers.

    Science.gov (United States)

    Jung, Sun hwa; Choi, Kihang; Pae, Ae Nim; Lee, Jae Kyun; Choo, Hyunah; Keum, Gyochang; Cho, Yong Seo; Min, Sun-Joon

    2014-12-21

    This article describes the rapid and diversified synthesis of pyrrolidinyl triazoles for the discovery of mitochondrial permeability transition pore (mPTP) blockers. The 1,3-dipolar cycloaddition of ethynyl trifluoroborate with azidopyrrolidine produced a key intermediate, triazolyl trifluoroborate 4, which subsequently underwent a Suzuki-Miyaura coupling reaction to afford a series of 1,4-disubstituted triazoles 2. Subsequent biological evaluation of these derivatives indicated 2ag and 2aj as the most potent mPTP blockers exhibiting excellent cytochrome P450 (CYP) stability when compared to the previously reported oxime analogue 1. The present work clearly demonstrates that a 1,2,3-triazole can be used as a stable oxime surrogate. Furthermore, it suggests that late-stage diversification through coupling reactions of organotrifluoroborates is suitable for the rapid discovery of biologically active molecules.

  10. Search for a Higgs-like boson decaying into bottom quarks in the ZH channel

    CERN Document Server

    Eller, Philipp David

    2013-01-01

    After the discovery of a Higgs-like Boson with a mass close to 125 GeV at the LHC in summer 2012, we are showing the update on the analysis of the VH cannel. In this channel the Higgs-like Boson is produced in association with a vector boson and decaying into b quarks. We present the updated results on the full 2011 and 2012 7+8 TeV dataset. This poster will focus on one of the tree modes that are combined in this analysis, where the associated vector boson is a Z boson that is decaying leptonically into two electrons or muons, respectively.

  11. Bosonic behavior of entangled fermions

    DEFF Research Database (Denmark)

    C. Tichy, Malte; Alexander Bouvrie, Peter; Mølmer, Klaus

    2012-01-01

    Two bound, entangled fermions form a composite boson, which can be treated as an elementary boson as long as the Pauli principle does not affect the behavior of many such composite bosons. The departure of ideal bosonic behavior is quantified by the normalization ratio of multi-composite-boson st......Two bound, entangled fermions form a composite boson, which can be treated as an elementary boson as long as the Pauli principle does not affect the behavior of many such composite bosons. The departure of ideal bosonic behavior is quantified by the normalization ratio of multi...

  12. Search for Higgs bosons at LEP2 and hadron colliders

    CERN Document Server

    Trefzger, T M

    2001-01-01

    The search for the Higgs boson was one of the most relevant issues of the final years of LEP running at high energies. An excess of 3 sigma beyond the background expectation has been found, consistent with the production of the Higgs boson with a mass near 115 GeV/c/sup 2/. At the upgraded Tevatron and at LHC the search for the Higgs boson will continue. At the Tevatron Higgs bosons can be detected with masses up to 180 GeV with an assumed total integrated luminosity of 20 fb/sup -1/. LHC has the potential to discover the Higgs boson in many different decay channels for Higgs masses up to 1 TeV. It will be possible to measure Higgs boson parameters, such as mass, width, and couplings to fermions and bosons. The results from Higgs searches at LEP2 and the possibilities for searches at hadron colliders will be reviewed. (156 refs).

  13. Discovery potential of xenon-based neutrinoless double beta decay experiments in light of small angular scale CMB observations

    CERN Document Server

    Gomez-Cadenas, J J; Vidal, J Muñoz; Peña-Garay, C

    2013-01-01

    The South Pole Telescope (SPT) has probed an expanded angular range of the CMB temperature power spectrum. Their recent analysis of the latest cosmological data prefers nonzero neutrino masses, mnu = 0.32+-0.11 eV. This result, if confirmed by the upcoming Planck data, has deep implications on the discovery of the nature of neutrinos. In particular, the values of the effective neutrino mass involved in neutrinoless double beta decay (bb0nu) are severely constrained for both the direct and inverse hierarchy, making a discovery much more likely. In this paper, we focus in xenon-based bb0nu experiments, on the double grounds of their good performance and the suitability of the technology to large-mass scaling. We show that the current generation, with effective masses in the range of 100 kg and conceivable exposures in the range of 500 kg year, could already have a sizable opportunity to observe bb0nu events, and their combined discovery potential is quite large. The next generation, with an exposure in the rang...

  14. Prospects for Higgs boson searches at the Large Hadron Collider

    Indian Academy of Sciences (India)

    B Mellado

    2009-01-01

    These proceedings summarize the sensitivity for the CMS and ATLAS experiments at the LHC to discover a Standard Model Higgs boson with relatively low integrated luminosity per experiment. The most relevant discovery modes are dealt with. A brief discussion on the expected performance from these experiments in searches for one or more of the Higgs bosons from the minimal version of the supersymmetric theories is also included.

  15. Discovery potential of xenon-based neutrinoless double beta decay experiments in light of small angular scale CMB observations

    Energy Technology Data Exchange (ETDEWEB)

    Gómez-Cadenas, J.J.; Martín-Albo, J.; Vidal, J. Muñoz; Peña-Garay, C., E-mail: gomez@mail.cern.ch, E-mail: jmalbos@ific.uv.es, E-mail: jmunoz@ific.uv.es, E-mail: penya@ific.uv.es [Instituto de Física Corpuscular (IFIC), CSIC and Universitat de Valencia Calle Catedrático José Beltrán, 2, 46090 Paterna, Valencia (Spain)

    2013-03-01

    The South Pole Telescope (SPT) has probed an expanded angular range of the CMB temperature power spectrum. Their recent analysis of the latest cosmological data prefers nonzero neutrino masses, with Σm{sub ν} = (0.32±0.11) eV. This result, if confirmed by the upcoming Planck data, has deep implications on the discovery of the nature of neutrinos. In particular, the values of the effective neutrino mass m{sub ββ} involved in neutrinoless double beta decay (ββ0ν) are severely constrained for both the direct and inverse hierarchy, making a discovery much more likely. In this paper, we focus in xenon-based ββ0ν experiments, on the double grounds of their good performance and the suitability of the technology to large-mass scaling. We show that the current generation, with effective masses in the range of 100 kg and conceivable exposures in the range of 500 kg·year, could already have a sizeable opportunity to observe ββ0ν events, and their combined discovery potential is quite large. The next generation, with an exposure in the range of 10 ton·year, would have a much more enhanced sensitivity, in particular due to the very low specific background that all the xenon technologies (liquid xenon, high-pressure xenon and xenon dissolved in liquid scintillator) can achieve. In addition, a high-pressure xenon gas TPC also features superb energy resolution. We show that such detector can fully explore the range of allowed effective Majorana masses, thus making a discovery very likely.

  16. Open Innovation Drug Discovery (OIDD): a potential path to novel therapeutic chemical space.

    Science.gov (United States)

    Alvim-Gaston, Maria; Grese, Timothy; Mahoui, Abdelaziz; Palkowitz, Alan D; Pineiro-Nunez, Marta; Watson, Ian

    2014-01-01

    The continued development of computational and synthetic methods has enabled the enumeration or preparation of a nearly endless universe of chemical structures. Nevertheless, the ability of this chemical universe to deliver small molecules that can both modulate biological targets and have drug-like physicochemical properties continues to be a topic of interest to the pharmaceutical industry and academic researchers alike. The chemical space described by public, commercial, in-house and virtual compound collections has been interrogated by multiple approaches including biochemical, cellular and virtual screening, diversity analysis, and in-silico profiling. However, current drugs and known chemical probes derived from these efforts are contained within a remarkably small volume of the predicted chemical space. Access to more diverse classes of chemical scaffolds that maintain the properties relevant for drug discovery is certainly needed to meet the increasing demands for pharmaceutical innovation. The Lilly Open Innovation Drug Discovery platform (OIDD) was designed to tackle barriers to innovation through the identification of novel molecules active in relevant disease biology models. In this article we will discuss several computational approaches towards describing novel, biologically active, drug-like chemical space and illustrate how the OIDD program may facilitate access to previously untapped molecules that may aid in the search for innovative pharmaceuticals.

  17. Higgs boson parameters and decays into fermions

    CERN Document Server

    Bluj, Michal Jacek

    2016-01-01

    In 2012 the discovery of a new boson with a mass of about 125 GeV and properties in agreement with those expected for the Higgs boson in the standard model was announced. In this note we review the results of searches for the fermionic decays the Higgs boson and the study of its properties performed with the proton-proton collision data recorded by the ATLAS and CMS detectors at the LHC in 2011 and 2012, corresponding to an integrated luminosity of approximately 5~fb$^{-1}$ and approximately 20~fb$^{-1}$ per experiment at $\\sqrt{s}=7$~TeV and $\\sqrt{s}=8$~TeV, respectively. Decay rates to fermions and extracted couplings are consistent with the expectation of the standard model. In addition, we present a search for lepton flavour violating decays of the Higgs boson which can occur in several extensions of the standard model, and a search for neutral Higgs bosons decaying to tau pairs performed in the context of the minimal supersymmetric extension of the standard model (MSSM).

  18. Enhanced Higgs boson to τ(+)τ(-) search with deep learning.

    Science.gov (United States)

    Baldi, P; Sadowski, P; Whiteson, D

    2015-03-20

    The Higgs boson is thought to provide the interaction that imparts mass to the fundamental fermions, but while measurements at the Large Hadron Collider (LHC) are consistent with this hypothesis, current analysis techniques lack the statistical power to cross the traditional 5σ significance barrier without more data. Deep learning techniques have the potential to increase the statistical power of this analysis by automatically learning complex, high-level data representations. In this work, deep neural networks are used to detect the decay of the Higgs boson to a pair of tau leptons. A Bayesian optimization algorithm is used to tune the network architecture and training algorithm hyperparameters, resulting in a deep network of eight nonlinear processing layers that improves upon the performance of shallow classifiers even without the use of features specifically engineered by physicists for this application. The improvement in discovery significance is equivalent to an increase in the accumulated data set of 25%.

  19. Small Molecules from Nature Targeting G-Protein Coupled Cannabinoid Receptors: Potential Leads for Drug Discovery and Development

    Directory of Open Access Journals (Sweden)

    Charu Sharma

    2015-01-01

    Full Text Available The cannabinoid molecules are derived from Cannabis sativa plant which acts on the cannabinoid receptors types 1 and 2 (CB1 and CB2 which have been explored as potential therapeutic targets for drug discovery and development. Currently, there are numerous cannabinoid based synthetic drugs used in clinical practice like the popular ones such as nabilone, dronabinol, and Δ9-tetrahydrocannabinol mediates its action through CB1/CB2 receptors. However, these synthetic based Cannabis derived compounds are known to exert adverse psychiatric effect and have also been exploited for drug abuse. This encourages us to find out an alternative and safe drug with the least psychiatric adverse effects. In recent years, many phytocannabinoids have been isolated from plants other than Cannabis. Several studies have shown that these phytocannabinoids show affinity, potency, selectivity, and efficacy towards cannabinoid receptors and inhibit endocannabinoid metabolizing enzymes, thus reducing hyperactivity of endocannabinoid systems. Also, these naturally derived molecules possess the least adverse effects opposed to the synthetically derived cannabinoids. Therefore, the plant based cannabinoid molecules proved to be promising and emerging therapeutic alternative. The present review provides an overview of therapeutic potential of ligands and plants modulating cannabinoid receptors that may be of interest to pharmaceutical industry in search of new and safer drug discovery and development for future therapeutics.

  20. Search for the Higgs boson in fermionic channels using the ATLAS detector

    Directory of Open Access Journals (Sweden)

    Hageböck Stephan

    2015-01-01

    Full Text Available Since the discovery of the Higgs boson by the ATLAS and CMS experiments at the LHC, the emphasis has shifted towards measurements of its properties. Of particular importance is the direct observation of the coupling of the Higgs boson to fermions. A review of ATLAS results in the search for the Higgs boson in tau, muon and b-quark pairs is presented.

  1. Where Is Higgs Boson?

    CERN Multimedia

    2008-01-01

    Quantum physicists think they know the answer. Probabilistic calculations reveal than the data provided by previous experiments has been miscalculated and that the Higgs boson has in fact been discovered. Weird! The Higgs boson is the only particle predicted by the Standard Model that hasn't been discovered yet.

  2. Measuring the 2HDM Scalar Potential at LHC14

    CERN Document Server

    Barger, Vernon; Jackson, Chris B; Peterson, Andrea D; Shaughnessy, Gabe

    2014-01-01

    After the extraordinary discovery of the Higgs boson at the LHC, the next goal is to pin down its underlying dynamics by measuring the Higgs self-couplings, along with its couplings to gauge and matter particles. As a prototype model of new physics in the scalar sector, we consider the Two Higgs Doublet Model (2HDM) with CP-conservation, and evaluate the prospects for measuring the trilinear scalar couplings among the CP-even Higgs bosons $h$ and $H$ ($\\lambda^{hhh}$, $\\lambda^{hhH}$, $\\lambda^{hHH}$) at LHC14. The continuum and resonant production of CP-even Higgs boson pairs, $hh$ and $hH$, offer complementary probes of the scalar potential away from the light-Higgs decoupling limit. We identify the viable search channels at LHC14 and estimate their expected discovery sensitivities.

  3. Detection of Z' Gauge Bosons in the Dimuon Decay Mode in CMS

    CERN Document Server

    Cousins, Robert; Valuev, Vyacheslav

    2006-01-01

    This note describes an update of a study of the potential of the CMS experiment to discover Z' gauge bosons in the Z' --> mu+ mu- decay channel. Unbinned maximum likelihood fits to mu+ mu- invariant mass distributions were used to extract signal and background contributions from fully-reconstructed sets of simulated events. Using signal and background shapes only, and taking into account realistic detector misalignment scenarios and various sources of systematic uncertainties, the discovery reach for a representative set of Z' models was found to be in the range between 2.9 and 3.8 TeV for an integrated luminosity of 10 fb^-1.

  4. Bosonization and Mirror Symmetry

    CERN Document Server

    Kachru, Shamit; Torroba, Gonzalo; Wang, Huajia

    2016-01-01

    We study bosonization in 2+1 dimensions using mirror symmetry, a duality that relates pairs of supersymmetric theories. Upon breaking supersymmetry in a controlled way, we dynamically obtain the bosonization duality that equates the theory of a free Dirac fermion to QED3 with a single scalar boson. This duality may be used to demonstrate the bosonization duality relating an $O(2)$-symmetric Wilson-Fisher fixed point to QED3 with a single Dirac fermion, Peskin-Dasgupta-Halperin duality, and the recently conjectured duality relating the theory of a free Dirac fermion to fermionic QED3 with a single flavor. Chern-Simons and BF couplings for both dynamical and background gauge fields play a central role in our approach. In the course of our study, we describe a chiral mirror pair that may be viewed as the minimal supersymmetric generalization of the two bosonization dualities.

  5. The Higgs boson

    CERN Document Server

    Pimenta, Jean Jûnio Mendes; Natti, Érica Regina Takano; Natti, Paulo Laerte

    2013-01-01

    The Higgs boson was predicted in 1964 by British physicist Peter Higgs. The Higgs is the key to explain the origin of the mass of other elementary particles of Nature. However, only with the coming into operation of the LHC, in 2008, there were technological conditions to search for the Higgs boson. Recently, a major international effort conducted at CERN, by means of ATLAS and CMS experiments, has enabled the observation of a new bosonic particle in the region of 125 GeVs. In this paper, by means of known mechanisms of symmetry breaking that occur in the BCS theory of superconductivity and in the theory of nuclear pairing, we discuss the Higgs mechanism in the Standard Model. Finally, we present the current state of research looking for the Higgs boson and the alternative theories and extensions of the Standard Model for the elementary particle physics. Keywords: Higgs boson, BCS theory, nuclear pairing, Higgs mechanism, Standard Model.

  6. Bosonization and mirror symmetry

    Science.gov (United States)

    Kachru, Shamit; Mulligan, Michael; Torroba, Gonzalo; Wang, Huajia

    2016-10-01

    We study bosonization in 2 +1 dimensions using mirror symmetry, a duality that relates pairs of supersymmetric theories. Upon breaking supersymmetry in a controlled way, we dynamically obtain the bosonization duality that equates the theory of a free Dirac fermion to QED3 with a single scalar boson. This duality may be used to demonstrate the bosonization duality relating an O (2 )-symmetric Wilson-Fisher fixed point to QED3 with a single Dirac fermion, Peskin-Dasgupta-Halperin duality, and the recently conjectured duality relating the theory of a free Dirac fermion to fermionic QED3 with a single flavor. Chern-Simons and BF couplings for both dynamical and background gauge fields play a central role in our approach. In the course of our study, we describe a "chiral" mirror pair that may be viewed as the minimal supersymmetric generalization of the two bosonization dualities.

  7. Production of electroweak bosons at hadron colliders: theoretical aspects

    CERN Document Server

    Mangano, Michelangelo L

    2016-01-01

    Since the W and Z discovery, hadron colliders have provided a fertile ground, in which continuously improving measurements and theoretical predictions allow to precisely determine the gauge boson properties, and to probe the dynamics of electroweak and strong interactions. This article will review, from a theoretical perspective, the role played by the study, at hadron colliders, of electroweak boson production properties, from the better understanding of the proton structure, to the discovery and studies of the top quark and of the Higgs, to the searches for new phenomena beyond the Standard Model.

  8. Production of Electroweak Bosons at Hadron Colliders: Theoretical Aspects

    Science.gov (United States)

    Mangano, Michelangelo L.

    2016-10-01

    Since the W± and Z0 discovery, hadron colliders have provided a fertile ground, in which continuously improving measurements and theoretical predictions allow to precisely determine the gauge boson properties, and to probe the dynamics of electroweak and strong interactions. This article will review, from a theoretical perspective, the role played by the study, at hadron colliders, of electroweak boson production properties, from the better understanding of the proton structure, to the discovery and studies of the top quark and of the Higgs, to the searches for new phenomena beyond the Standard Model.

  9. Therapeutic Potential of Plants as Anti-Microbials for Drug Discovery

    Directory of Open Access Journals (Sweden)

    Ramar Perumal Samy

    2010-01-01

    Full Text Available The uses of traditional medicinal plants for primary health care have steadily increased worldwide in recent years. Scientists are in search of new phytochemicals that could be developed as useful anti-microbials for treatment of infectious diseases. Currently, out of 80% of pharmaceuticals derived from plants, very few are now being used as anti-microbials. Plants are rich in a wide variety of secondary metabolites that have found anti-microbial properties. This review highlights the current status of traditional medicine, its contribution to modern medicine, recent trends in the evaluation of anti-microbials with a special emphasis upon some tribal medicine, in vitro and in vivo experimental design for screening, and therapeutic efficacy in safety and human clinical trails for commercial outlet. Many of these commercially available compounds are crude preparations administered without performing human clinical trials. Recent methods are useful to standardize the extraction for scientific investigation of new phytochemicals and anti-microbials of traditionally used plants. It is concluded that once the local ethnomedical preparations of traditional sources are scientifically evaluated before dispensing they should replace existing drugs commonly used for the therapeutic treatment of infection. This method should be put into practice for future investigations in the field of ethnopharmacology, phytochemistry, ethnobotany and other biological fields for drug discovery.

  10. Discovery of potential cholesterol esterase inhibitors using in silico docking studies

    Directory of Open Access Journals (Sweden)

    Thirumalaisamy Sivashanmugam

    2013-08-01

    Full Text Available New drug discovery is considered broadly in terms of two kinds of investiga-tional activities such as exploration and exploitation. This study deals with the evaluation of the cholesterol esterase inhibitory activity of flavonoids apigenin, biochanin, curcumin, diosmetin, epipervilline, glycitein, okanin, rhamnazin and tangeritin using in silico docking studies. In silico docking studies were carried out using AutoDock 4.2, based on the Lamarckian genetic algorithm principle. The results showed that all the selected flavonoids showed binding energy ranging between -7.08 kcal/mol to -5.64 kcal/mol when compared with that of the standard compound gallic acid (-4.11 kcal/mol. Intermolecular energy (-9.13 kcal/mol to -7.09 kcal/mol and inhibition constant (6.48 µM to 73.18 µM of the ligands also coincide with the binding energy. All the selected flavonoids contributed cholesterol esterase inhibitory activity, these molecular docking analyses could lead to the further develop-ment of potent cholesterol esterase inhibitors for the treatment of obesity.

  11. Mesua beccariana (Clusiaceae, A Source of Potential Anti-cancer Lead Compounds in Drug Discovery

    Directory of Open Access Journals (Sweden)

    Soek Sin Teh

    2012-09-01

    Full Text Available An investigation on biologically active secondary metabolites from the stem bark of Mesua beccariana was carried out. A new cyclodione, mesuadione (1, along with several known constituents which are beccamarin (2, 2,5-dihydroxy-1,3,4-trimethoxy anthraquinone (3, 4-methoxy-1,3,5-trihydroxyanthraquinone (4, betulinic acid (5 and stigmasterol (6 were obtained from this ongoing research. Structures of these compounds were elucidated by extensive spectroscopic methods, including 1D and 2D-NMR, GC-MS, IR and UV techniques. Preliminary tests of the in vitro cytotoxic activities of all the isolated metabolites against a panel of human cancer cell lines Raji (lymphoma, SNU-1 (gastric carcinoma, K562 (erythroleukemia cells, LS-174T (colorectal adenocarcinoma, HeLa (cervical cells, SK-MEL-28 (malignant melanoma cells, NCI-H23 (lung adenocarcinoma, IMR-32 (neuroblastoma and Hep-G2 (hepatocellular liver carcinoma were carried out using an MTT assay. Mesuadione (1, beccamarin (2, betulinic acid (5 and stigmasterol (6 displayed strong inhibition of Raji cell proliferation, while the proliferation rate of SK-MEL-28 and HeLa were strongly inhibited by stigmasterol (6 and beccamarin (2, indicating these secondary metabolites could be anti-cancer lead compounds in drug discovery.

  12. The discovery of antidepressant drugs by computer-analyzed human cerebral bio-electrical potentials (CEEG).

    Science.gov (United States)

    Itil, T M

    1983-01-01

    Antidepressant properties of six compounds were predicted based on their computer-analyzed human electroencephalographical (CEEG) profiles. The clinical investigations with mianserin (GB-94) confirmed the CEEG prediction. This compound has now been marketed as the first antidepressant of which the clinical effects were discovered solely by the quantitative pharmaco-EEG method. As predicted by the CEEG, clinical antidepressant properties of GC-46, mesterolone, and estradiol valerate were observed in preliminary investigations. No extensive studies with definite statistical results were yet carried out with these compounds. No systematic large studies could be conducted with cyclozocine and cyproterone acetate because of the intolerable side effects with these compounds. The optical isomers of mianserin, GF-59 and GF-60, both predicted as antidepressant by the computer EEG data base, have not yet been tested in depressive patients. None of these compounds possess the "typical" pharmacological and/or biochemical profiles of marketed antidepressants. Thus, the discovery of the established antidepressant properties of mianserin (GB-94) by computer analyzed EEG method challenges the well-known biochemical hypotheses of depression and the "classical" development of antidepressant drugs.

  13. Potential of Glutamate-Based Drug Discovery for Next Generation Antidepressants

    Directory of Open Access Journals (Sweden)

    Shigeyuki Chaki

    2015-09-01

    Full Text Available Recently, ketamine has been demonstrated to exert rapid-acting antidepressant effects in patients with depression, including those with treatment-resistant depression, and this discovery has been regarded as the most significant advance in drug development for the treatment of depression in over 50 years. To overcome unwanted side effects of ketamine, numerous approaches targeting glutamatergic systems have been vigorously investigated. For example, among agents targeting the NMDA receptor, the efficacies of selective GluN2B receptor antagonists and a low-trapping antagonist, as well as glycine site modulators such as GLYX-13 and sarcosine have been demonstrated clinically. Moreover, agents acting on metabotropic glutamate receptors, such as mGlu2/3 and mGlu5 receptors, have been proposed as useful approaches to mimicking the antidepressant effects of ketamine. Neural and synaptic mechanisms mediated through the antidepressant effects of ketamine have been being delineated, most of which indicate that ketamine improves abnormalities in synaptic transmission and connectivity observed in depressive states via the AMPA receptor and brain-derived neurotrophic factor-dependent mechanisms. Interestingly, some of the above agents may share some neural and synaptic mechanisms with ketamine. These studies should provide important insights for the development of superior pharmacotherapies for depression with more potent and faster onsets of actions.

  14. Solution of the dilaton problem in open bosonic string theories

    Energy Technology Data Exchange (ETDEWEB)

    Bern, Z. (Los Alamos National Lab., NM (United States)); Dunbar, D.C. (Liverpool Univ. (United Kingdom))

    1991-01-01

    One of the most remarkable features of string theories is that they seem to provide a framework for a consistent theory of quantum gravity which is unified with all other forces. String theories fall into the two basic, a priori equally interesting, categories of open and closed string theories. For the past five years virtually all attention has been focused on purely closed string theories even though the reincarnation of string theory began with the discovery of anomaly cancellation and finiteness in the Green-Schwarz open superstring. It is the authors' purpose in this essay to rekindle interest in open string theories as potential theories of nature, including gravity. All string theories naively contain a massless dilaton which couples with the strength of gravity in direct violation of experiment. They present a simple mechanism for giving the dilaton a mass in unoriented open bosonic string theories.

  15. Macchines per scoprire - Discovery Machines

    CERN Multimedia

    Auditorium, Rome

    2016-01-01

    During the FCC week 2016 a public event entitled “Discovery Machines: The Higgs Boson and the Search for New Physics took place on 14 April at the Auditorium in Rome. The event, brought together physicists and experts from economics to discuss intriguing questions on the origin and evolution of the Universe and the societal impact of large-scale research projects.

  16. On the Non-Minimal Coupling of the Higgs Boson to Gravity

    CERN Document Server

    Atkins, Michael

    2013-01-01

    We derive the first bound on the value of the Higgs boson non-minimal coupling to the Ricci scalar. We show that the recent discovery of the Higgs boson at the Large Hadron Collider at CERN implies that the non-minimal coupling is smaller than $1.7\\times 10^{15}$.

  17. Biological evaluation of endophytic fungus, Chaetomium globosum JN711454, as potential candidate for improving drug discovery.

    Science.gov (United States)

    Selim, Khaled A; El-Beih, Ahmed A; Abdel-Rahman, Tahany M; El-Diwany, Ahmed I

    2014-01-01

    The main objective of this research work focused on investigating the biological and chemical aspects of endophytic fungus Chaetomium globosum, for pharmaceutical purposes to improve the drug discovery process. The endophytic C. globosum was isolated from healthy leaves of Egyptian medicinal plant Adiantum capillus-veneris collected from Saint Katherine Protectorate, Sinai, Egypt. The identification of C. globosum was on the basis of classical and molecular taxonomy. Gene encoding for 18S rRNA was partially sequenced, submitted to the GenBank and got the accession number JN711454, to resolve the phylogenetic relations with fungal ancestor using phylogenetic tree. To explore the biosynthetic power of endophytic C. globosum JN711454, the fungus was cultivated over five different media, oatmeal, rice, yeast malt glucose, potato dextrose agar (PDA) and Czapek's dox media, for 3 weeks at 30 °C, followed by extraction with different solvents, ethyl acetate (EA), and methanol. The ethyl acetate extract of C. globosum cultivated on PDA medium was the most potent extract. It showed strong antioxidant activity with EC50 11.5 μg/ml, potent anticancer activity with 55 % toxicity toward HepG-2 cells at 100 μg/ml and 66 % cytotoxicity to FGC4 cells at 250 μg/ml, promising butyrylcholinesterase inhibitory activities (>85 %), and moderate antimicrobial and stopped the attachment of HSV-2 virus to VERO cells. The metabolomic profiling of PDA-EA extract using LC-MS revealed the presence of several metabolites to which the observed bioactivities could be attributed. Here we report for the first time inhibitory activity of endophytic C. globosum JN711454 secondary metabolites to butyrylcholinesterase, one of neuro hydrolase enzymes that play a major role in development of Alzheimer's disease.

  18. Studies of b-associated production and muonic decays of neutral Higgs bosons at the ATLAS experiment within the Minimal Supersymmetric Standard Model

    Energy Technology Data Exchange (ETDEWEB)

    Warsinsky, Markus

    2008-09-15

    This thesis presents a Monte Carlo study of neutral Higgs bosons of the Minimal Supersymmetric Standard Model (MSSM) decaying into muons at the ATLAS experiment at the CERN Large Hadron Collider. Signal and background processes are simulated using novel Monte Carlo generators that incorporate parts of higher order corrections and are expected to give a more accurate prediction than previous programs. The SHERPA Monte Carlo generator is validated for its use in the analysis and compared to results obtained with other programs. Where possible, the Monte Carlo event samples are normalized to higher order calculations. To increase the available Monte Carlo statistics, this study is based on the ATLAS fast detector simulation ATLFAST. Differences between ATLFAST and the detailed detector simulation of ATLAS are examined, and, where possible, correction procedures are devised. A cut based analysis is performed assuming an integrated luminosity of 30 fb{sup -1}, and optimized with respect to the discovery potential for MSSM Higgs bosons. The systematic uncertainties of the event selection and the Monte Carlo predictions are estimated. A method that can be used to estimate the background from data is presented and evaluated. Last, the discovery potential of the ATLAS experiment in the CP conserving benchmark scenarios of the MSSM is evaluated. One or more of the neutral Higgs bosons of the MSSM can be discovered in the muonic decay mode using 30 fb{sup -1} of data for low masses of the pseudoscalar boson A{sup 0}, if the model parameter tan {beta} is at least 20. For higher masses of the A{sup 0}, tan {beta} would need to be significantly higher to ensure a discovery in the studied decay channel. The sensitivity of ATLAS to MSSM Higgs bosons is multiple times larger than the one of previous and currently running experiments. (orig.)

  19. The discovery of potential acetylcholinesterase inhibitors: A combination of pharmacophore modeling, virtual screening, and molecular docking studies

    Directory of Open Access Journals (Sweden)

    Chuang Chih-Kuang

    2011-01-01

    Full Text Available Abstract Background Alzheimer's disease (AD is the most common cause of dementia characterized by progressive cognitive impairment in the elderly people. The most dramatic abnormalities are those of the cholinergic system. Acetylcholinesterase (AChE plays a key role in the regulation of the cholinergic system, and hence, inhibition of AChE has emerged as one of the most promising strategies for the treatment of AD. Methods In this study, we suggest a workflow for the identification and prioritization of potential compounds targeted against AChE. In order to elucidate the essential structural features for AChE, three-dimensional pharmacophore models were constructed using Discovery Studio 2.5.5 (DS 2.5.5 program based on a set of known AChE inhibitors. Results The best five-features pharmacophore model, which includes one hydrogen bond donor and four hydrophobic features, was generated from a training set of 62 compounds that yielded a correlation coefficient of R = 0.851 and a high prediction of fit values for a set of 26 test molecules with a correlation of R2 = 0.830. Our pharmacophore model also has a high Güner-Henry score and enrichment factor. Virtual screening performed on the NCI database obtained new inhibitors which have the potential to inhibit AChE and to protect neurons from Aβ toxicity. The hit compounds were subsequently subjected to molecular docking and evaluated by consensus scoring function, which resulted in 9 compounds with high pharmacophore fit values and predicted biological activity scores. These compounds showed interactions with important residues at the active site. Conclusions The information gained from this study may assist in the discovery of potential AChE inhibitors that are highly selective for its dual binding sites.

  20. The battle of Alzheimer disease - the beginning of the futureUnleashing the potential of academic discoveries

    Directory of Open Access Journals (Sweden)

    Johan eLundkvist

    2014-05-01

    Full Text Available Alzheimer Disease (AD is the most common form of dementia, affecting approximately 36 million people worldwide. To date there is no preventive or curative treatment available for AD, and in absence of major progress in therapeutic development, AD manifests a concrete socioeconomic threat. The awareness of the growing problem of AD is increasing, exemplified by the recent G8 Dementia Summit, a meeting held in order to set the stage and steer the compass for the future. Simultaneously, and paradoxically, we have seen key players in the pharmaceutical industry that have recently closed or significantly decreased their R&D spending on AD and other CNS disorders. Given the pressing need for new treatments in this area, other actors need to step-in and enter this drug discovery arena complementing the industrial efforts, in order to turn biological and technological progress into novel therapeutics. In this article, we present an example of a novel drug discovery initiative that in a non-profit setting, aims to integrate with both preclinical and clinical academic groups and pharmaceutical industry to explore the therapeutic potential of new concepts in patients, using novel biology, state of the art technologies and rapid concept

  1. Higgs Boson - on Your Own

    CERN Document Server

    Csorgo, T

    2013-01-01

    One of the highlights of 2012 in physics is related to two papers, published by the ATLAS and the CMS Collaborations, that announced the discovery of at least one new particle in pp collisions at CERN LHC. At least one of the properties of this new particle is found to be similar to that of the Higgs boson, the last and most difficult to find building block from the Standard Model of particle physics. Physics teachers are frequently approached by their media-educated students, who inquire about the properties of the Higgs boson, but physics teachers are rarely trained to teach this elusive aspect of particle physics in elementary, middle or junior high schools. In this paper I describe a card-game, that can be considered as a hands-on and easily accessible tool that allows interested teachers, students and also motivated lay-persons to play with the properties of the newly found Higgs-like particle. This new particle was detected through its decays to directly observable, final state particles. Many of these ...

  2. From The Beatles to Bosons

    CERN Multimedia

    Stephanie McClellan

    2013-01-01

    Before embarking on a successful career as a musician, Alan Parsons started out as a sound engineer - earning his first credit on The Beatles’ Abbey Road.  Over the years, he has worked and collaborated with various artists, but 30 September 2013 marks a unique collaboration.  For CERN’s ‘Bosons & More’ party, Alan Parsons Live Project will be sharing the stage with the Orchestre de la Suisse Romande.  Having already visited CERN in 2011, Alan Parsons provides an insight into his views on science and his upcoming performance at the ‘Bosons & More’ event.     Alan Parsons during his visit to CERN in August 2011. Since visiting CERN in 2011, how have your feelings towards the Organization developed? I was thrilled to hear about the recent discovery and how years of work had paid off. Together with my wife, Lisa, and my band, we were very privileged to come to CERN a couple of years ago, hav...

  3. Search for a Higgs boson produced in association with a W boson at ATLAS

    Energy Technology Data Exchange (ETDEWEB)

    Ruckert, Benjamin

    2009-11-23

    The Large Hadron Collider at CERN the most modern proton-proton collider and data taking will start in 2009, with a centre-of-mass energy of {radical}(s) = 7 TeV. The ATLAS detector, which is one of two multi-purpose detectors at the Large Hadron Collider, is able to detect a Standard Model Higgs boson if it exists. This is one of the main tasks of the ATLAS experiment. This thesis deals with a Standard Model Higgs boson produced in association with a W boson. The Monte Carlo study is based on physics events generated at the nominal centre-of-mass energy of the Large Hadron Collider of {radical}(s) = 14 TeV. Large parts of this analysis have been done using the global Grid infrastructure of the Large Hadron Collider experiments. A mass range of the Higgs boson of m{sub H} = 130 - 190 GeV has been taken into account. In this mass range, the Higgs boson dominantly decays into a pair of W bosons, leading to initially three W bosons: WH{yields}WWW. Two orthogonal analysis channels have been investigated in detailed studies of the background properties. The first channel considers the leptonic decay of two W bosons, such that the leptons are of opposite charge. The third W boson then decays hadronically. The analysis is based on one-dimensional cuts, where the best cuts found are strict cuts on the transverse momenta of the leptons, a cut on the invariant mass of the jets, as well as a cut on the transverse jet momenta and the missing transverse energy. The second decay channel studied is dedicated to the leptonic decay of all three W bosons. Again, cuts on the transverse momenta of the leptons and the jets have been proven to be efficient, as well as the use of the spatial correlation of the decay products of the Higgs boson. The invariant mass of the leptons with opposite sign has been emerged as a very efficient cut to reject dominant diboson background contributions. The discovery reach of both channels separately as well as the combination has been calculated using

  4. Detection of Heavy Majorana Neutrinos and Right-Handed Bosons

    CERN Document Server

    Gninenko, Sergei; Krasnikov, Nikolai; Matveev, Viktor

    2006-01-01

    The SU_C(3) otimes SU_L(2) otimes SU_R(2) otimes U(1) left-right (LR) symmetric model explains the origin of the parity violation in weak interactions and predicts the existence of additional W_R and Z' gauge bosons. In addition, heavy right-handed Majorana neutrino states N arise naturally within LR symmetric model. The N s could be partners of light neutrino states, related to their non-zero masses through the see-saw mechanism. This makes the searches of W_R, Z' and N interesting and important. This note describes the study of the potential of the CMS experiment to observe signals from the N and W_R production at the LHC. It is shown that their decay signals can be identified with a small background. For the integral LHC luminosity of L_t = 30 fb^ -1, the 5 sigma discovery of W_R - boson and heavy Majorana neutrinos N_e with masses up to 3.5 TeV and 2.3 TeV, respectively is found possible.

  5. In Silico discovery of transcription factors as potential diagnostic biomarkers of ovarian cancer

    KAUST Repository

    Kaur, Mandeep

    2011-09-19

    Background: Our study focuses on identifying potential biomarkers for diagnosis and early detection of ovarian cancer (OC) through the study of transcription regulation of genes affected by estrogen hormone.Results: The results are based on a set of 323 experimentally validated OC-associated genes compiled from several databases, and their subset controlled by estrogen. For these two gene sets we computationally determined transcription factors (TFs) that putatively regulate transcription initiation. We ranked these TFs based on the number of genes they are likely to control. In this way, we selected 17 top-ranked TFs as potential key regulators and thus possible biomarkers for a set of 323 OC-associated genes. For 77 estrogen controlled genes from this set we identified three unique TFs as potential biomarkers.Conclusions: We introduced a new methodology to identify potential diagnostic biomarkers for OC. This report is the first bioinformatics study that explores multiple transcriptional regulators of OC-associated genes as potential diagnostic biomarkers in connection with estrogen responsiveness. We show that 64% of TF biomarkers identified in our study are validated based on real-time data from microarray expression studies. As an illustration, our method could identify CP2 that in combination with CA125 has been reported to be sensitive in diagnosing ovarian tumors. 2011 Kaur et al; licensee BioMed Central Ltd.

  6. In Silico discovery of transcription factors as potential diagnostic biomarkers of ovarian cancer

    Directory of Open Access Journals (Sweden)

    Choolani Mahesh

    2011-09-01

    Full Text Available Abstract Background Our study focuses on identifying potential biomarkers for diagnosis and early detection of ovarian cancer (OC through the study of transcription regulation of genes affected by estrogen hormone. Results The results are based on a set of 323 experimentally validated OC-associated genes compiled from several databases, and their subset controlled by estrogen. For these two gene sets we computationally determined transcription factors (TFs that putatively regulate transcription initiation. We ranked these TFs based on the number of genes they are likely to control. In this way, we selected 17 top-ranked TFs as potential key regulators and thus possible biomarkers for a set of 323 OC-associated genes. For 77 estrogen controlled genes from this set we identified three unique TFs as potential biomarkers. Conclusions We introduced a new methodology to identify potential diagnostic biomarkers for OC. This report is the first bioinformatics study that explores multiple transcriptional regulators of OC-associated genes as potential diagnostic biomarkers in connection with estrogen responsiveness. We show that 64% of TF biomarkers identified in our study are validated based on real-time data from microarray expression studies. As an illustration, our method could identify CP2 that in combination with CA125 has been reported to be sensitive in diagnosing ovarian tumors.

  7. Search for a charged Higgs boson in $\\tau\

    CERN Document Server

    AUTHOR|(INSPIRE)INSPIRE-00011001; Gallinaro, Michele

    The Large Hadron Collider (LHC) started the first proton-proton collisions at a center-of-mass energy of 7 TeV in 2010. Soon thereafter, the experiments started collecting data and were able to rediscover the Standard Model (SM) in a few months, thanks to the very good understanding of the detectors, and their already precise calibrations. The LHC took data at $\\sqrt{s}=7$~TeV and 8~TeV in the years 2010-2011 and 2012, respectively: the peak of his intensive data taking has been, in 2012, the discovery, by the CMS and ATLAS experiment s, of a neutral boson with a mass of approximately 125\\unit{\\GeV}. The properties of the new boson are consistent with those predicted for the Standard Model (SM) Higgs boson, and models with an extended Higgs sector are constrained by the measured properties of the new boson: the discovery of another scalar boson, neutral or charged, would represent unambig uous evidence for the presence of physics beyond the SM. Charged Higgs bosons are predicted in models consisting of at...

  8. Integrative genomic data mining for discovery of potential blood-borne biomarkers for early diagnosis of cancer.

    Directory of Open Access Journals (Sweden)

    Yongliang Yang

    Full Text Available BACKGROUND: With the arrival of the postgenomic era, there is increasing interest in the discovery of biomarkers for the accurate diagnosis, prognosis, and early detection of cancer. Blood-borne cancer markers are favored by clinicians, because blood samples can be obtained and analyzed with relative ease. We have used a combined mining strategy based on an integrated cancer microarray platform, Oncomine, and the biomarker module of the Ingenuity Pathways Analysis (IPA program to identify potential blood-based markers for six common human cancer types. METHODOLOGY/PRINCIPAL FINDINGS: In the Oncomine platform, the genes overexpressed in cancer tissues relative to their corresponding normal tissues were filtered by Gene Ontology keywords, with the extracellular environment stipulated and a corrected Q value (false discovery rate cut-off implemented. The identified genes were imported to the IPA biomarker module to separate out those genes encoding putative secreted or cell-surface proteins as blood-borne (blood/serum/plasma cancer markers. The filtered potential indicators were ranked and prioritized according to normalized absolute Student t values. The retrieval of numerous marker genes that are already clinically useful or under active investigation confirmed the effectiveness of our mining strategy. To identify the biomarkers that are unique for each cancer type, the upregulated marker genes that are in common between each two tumor types across the six human tumors were also analyzed by the IPA biomarker comparison function. CONCLUSION/SIGNIFICANCE: The upregulated marker genes shared among the six cancer types may serve as a molecular tool to complement histopathologic examination, and the combination of the commonly upregulated and unique biomarkers may serve as differentiating markers for a specific cancer. This approach will be increasingly useful to discover diagnostic signatures as the mass of microarray data continues to grow in the

  9. Discovery of a new HIV-1 inhibitor scaffold and synthesis of potential prodrugs of indazoles.

    Science.gov (United States)

    Kim, Se-Ho; Markovitz, Benjamin; Trovato, Richard; Murphy, Brett R; Austin, Harry; Willardsen, Adam J; Baichwal, Vijay; Morham, Scott; Bajji, Ashok

    2013-05-15

    A new oxazole scaffold showing great promise in HIV-1 inhibition has been discovered by cell-based screening of an in-house library and scaffold modification. Follow-up SAR study focusing on the 5-aryl substituent of the oxazole core has identified 4k (EC50=0.42μM, TI=50) as a potent inhibitor. However, the analogues suffered from poor aqueous solubility. To address this issue, we have developed broadly applicable potential prodrugs of indazoles. Among them, N-acyloxymethyl analogue 11b displayed promising results (i.e., increased aqueous solubility and susceptibility to enzymatic hydrolysis). Further studies are warranted to fully evaluate the analogues as the potential prodrugs with improved physiochemical and PK properties.

  10. Discovery of wall teichoic acid inhibitors as potential anti-MRSA β-lactam combination agents.

    Science.gov (United States)

    Wang, Hao; Gill, Charles J; Lee, Sang H; Mann, Paul; Zuck, Paul; Meredith, Timothy C; Murgolo, Nicholas; She, Xinwei; Kales, Susan; Liang, Lianzhu; Liu, Jenny; Wu, Jin; Santa Maria, John; Su, Jing; Pan, Jianping; Hailey, Judy; Mcguinness, Debra; Tan, Christopher M; Flattery, Amy; Walker, Suzanne; Black, Todd; Roemer, Terry

    2013-02-21

    Innovative strategies are needed to combat drug resistance associated with methicillin-resistant Staphylococcus aureus (MRSA). Here, we investigate the potential of wall teichoic acid (WTA) biosynthesis inhibitors as combination agents to restore β-lactam efficacy against MRSA. Performing a whole-cell pathway-based screen, we identified a series of WTA inhibitors (WTAIs) targeting the WTA transporter protein, TarG. Whole-genome sequencing of WTAI-resistant isolates across two methicillin-resistant Staphylococci spp. revealed TarG as their common target, as well as a broad assortment of drug-resistant bypass mutants mapping to earlier steps of WTA biosynthesis. Extensive in vitro microbiological analysis and animal infection studies provide strong genetic and pharmacological evidence of the potential effectiveness of WTAIs as anti-MRSA β-lactam combination agents. This work also highlights the emerging role of whole-genome sequencing in antibiotic mode-of-action and resistance studies.

  11. Selective androgen receptor modulators in drug discovery: medicinal chemistry and therapeutic potential.

    Science.gov (United States)

    Cadilla, Rodolfo; Turnbull, Philip

    2006-01-01

    Modulation of the androgen receptor has the potential to be an effective treatment for hypogonadism, andropause, and associated conditions such as sarcopenia, osteoporosis, benign prostatic hyperplasia, and sexual dysfunction. Side effects associated with classical anabolic steroid treatments have driven the quest for drugs that demonstrate improved therapeutic profiles. Novel, non-steroidal compounds that show tissue selective activity and improved pharmacokinetic properties have been developed. This review provides an overview of current advances in the development of selective androgen receptor modulators (SARMs).

  12. A Historical Profile of the Higgs Boson

    CERN Document Server

    Ellis, John; Nanopoulos, V

    2016-01-01

    The Higgs boson was postulated in 1964, and phenomenological studies of its possible production and decays started in the early 1970s, followed by studies of its possible production in e+ e−, and pp collisions, in particular. Until recently, the most sensitive searches for the Higgs boson were at LEP between 1989 and 2000, which were complemented by searches at the Fermilab Tevatron. Then the LHC experiments ATLAS and CMS entered the hunt, announcing on July 4, 2012 the discovery of a "Higgs-like" particle with a mass of about 125 GeV. This identification has been supported by subsequent measurements of its spin, parity and coupling properties. It was widely anticipated that the Higgs boson would be accompanied by supersymmetry, although other options, like compositeness, were not completely excluded. So far there are no signs of any new physics, and the measured properties of the Higgs boson are consistent with the predictions of the minimal Standard Model. This article reviews some of the key historical d...

  13. Search for a Higgs-like boson decaying into bottom quarks in the Z(IIH channel

    Directory of Open Access Journals (Sweden)

    Eller Philipp

    2013-11-01

    Full Text Available After the discovery of a Higgs-like Boson with a mass close to 125 GeV at the LHC in summer 2012, we are showing the update on the analysis of the VH cannel. In this channel the Higgs-like Boson is produced in association with a vector boson and decaying into b quarks. We present the updated results on the full 2011 and 2012 7+8 TeV dataset. This poster will focus on one of the tree modes that are combined in this analysis, where the associated vector boson is a Z boson that is decaying leptonically into two electrons or muons, respectively.

  14. Measurement of the W boson mass with the ATLAS detector

    CERN Document Server

    Balli, Fabrice; The ATLAS collaboration

    2017-01-01

    A precise measurement of the mass of the W boson mass represents an important milestone to test the overall consistency of the Standard Model. Since the discovery of a Higgs Boson, the W boson mass is predicted to 7 MeV precision, while the world average of all measurements is 15 MeV, making the improved measurement an important goal. The ATLAS experiment at the LHC represents an ideal laboratory for such a precise measurement. Large samples of many millions of leptonic decays of W and Z bosons were collected with efficient single lepton triggers in the 7 TeV data set corresponding to an integrated luminosity of 4.6/fb. With these samples the detector and physics modelling has been studied in great detail to enable a systematic uncertainty on the measurement that approaches the statistical power of the data of 7 MeV per decay channel as far as possible.

  15. Sakurai Prize: Beyond the Standard Model Higgs Boson

    Science.gov (United States)

    Haber, Howard

    2017-01-01

    The discovery of the Higgs boson strongly suggests that the first elementary spin 0 particle has been observed. Is the Higgs boson a solo act, or are there additional Higgs bosons to be discovered? Given that there are three generations of fundamental fermions, one might also expect the sector of fundamental scalars of nature to be non-minimal. However, there are already strong constraints on the possible structure of an extended Higgs sector. In this talk, I review the theoretical motivations that have been put forward for an extended Higgs sector and discuss its implications in light of the observation that the properties of the observed Higgs boson are close to those predicted by the Standard Model. supported in part by the U.S. Department of Energy Grant Number DE-SC0010107.

  16. Pharmacophore development and screening for discovery of potential inhibitors of ADAMTS-4 for osteoarthritis therapy.

    Science.gov (United States)

    Verma, Priyanka; Dalal, Krishna; Chopra, Madhu

    2016-08-01

    In the development of osteoarthritis, aggrecan degrades prior to cartilage destruction. Aggrecanase-1 (ADAMTS-4) is considered to be the major enzyme responsible for cleaving the Glu373-Ala374 bond in the interglobular domain of aggrecan in humans. Therefore, inhibitors of ADAMTS-4 have therapeutic potential in the treatment of osteoarthritis. In the present work, we developed a chemical feature based pharmacophore model of ADAMTS-4 inhibitors using the HipHop module within the Catalyst program package in order to elucidate the structure-activity relationship and to carry out in-silico screening. The Maybridge database was screened using Hypo1 as a 3D query, and the best-fit hits that followed Lipinski's rule of five were subsequently screened to select the compounds. The hit compounds were then docked into the active site of ADAMTS-4, and interactions were visualized to determine the potential lead molecules. After subjecting all of the hits to various screening and filtering processes, 13 compounds were finally evaluated for their in vitro inhibitory activities. This study resulted in the identification of two lead compounds with potent inhibitory effects on ADAMTS-4 activity, with IC50 values of 0.042 μM and 0.028 μM, respectively. These results provide insight into the pharmacophoric requirements for the development of more potent ADAMTS-4 inhibitors. Graphical Abstract The aggrecan-degrading metalloprotease ADAMTS-4 has been identified as a novel therapeutic target for osteoarthritis. In this work, we used HipHop-based pharmacophore modeling and virtual screening of the Maybridge database to identify novel ADAMTS-4 inhibitors. These novel lead compounds act as potent and specific inhibitors for the ADAMTS-4 enzyme and could have therapeutic potential in the treatment of OA.

  17. Search for the Higgs boson in fermionic channels using the ATLAS detector

    CERN Document Server

    Dell'Asta, L; The ATLAS collaboration

    2014-01-01

    Since the discovery of a Higgs-like boson by the ATLAS and CMS experiments at the LHC, the emphasis has shifted towards measurements of its properties and the search in the less sensitive channels in order to determine whether the new particle is the Standard Model (SM) Higgs boson. Of particular importance is the direct observation of the coupling of the Higgs boson to fermions. In this presentation a review of ATLAS results in the search for the Higgs boson in muon, tau-lepton, b-quark pair decay channels will be given.

  18. Search for a Higgs boson in fermion modes using the ATLAS detector.

    CERN Document Server

    Aben, RZ; The ATLAS collaboration

    2013-01-01

    Since the discovery of a Higgs-like boson by the ATLAS and CMS experiments at the LHC, the emphasis has shifted towards measurements of its properties in order to determine whether the new particle is the Standard Model (SM) Higgs boson, or something else. Of particular importance is the direct observation of the coupling of the Higgs boson to fermions. In this presentation a comprehensive review of ATLAS results in the search for the Higgs boson in the main fermion decay (bb and tautau) channels and in various production modes (VBF, VH, ttH, and gluon fusion) will be given.

  19. Search for the Higgs boson in VH(bb) channel using the ATLAS detector

    CERN Document Server

    Francavilla, P; The ATLAS collaboration

    2014-01-01

    Since the discovery of a Higgs boson by the ATLAS and CMS experiments at the LHC, the emphasis has shifted towards measurements of its properties and the search for less sensitive channels in order to determine whether the new particle is the Standard Model (SM) Higgs boson. Of particular importance is the direct observation of the coupling of the Higgs boson to b-quarks. In this talk a review of ATLAS results in the search for the Higgs boson in the VH production mode with the Higgs decaying to a b-quark pair decay will be given.

  20. Search for the Higgs boson in $\\tau^+\\tau^-$ channel using the ATLAS detector

    CERN Document Server

    O'Neil, D C; The ATLAS collaboration

    2013-01-01

    Since the discovery of a Higgs-­like boson by the ATLAS and CMS experiments at the LHC, the emphasis has shifted towards measurements of its properties and the search for the search in the less sensitive channels in order to determine whether the new particle is the Standard Model (SM) Higgs boson. Of particular importance is the direct observation of the coupling of the Higgs boson to leptons. In this presentation a comprehensive review of ATLAS results in the search for the Higgs boson in the tau-­tau decay channel and in various production modes (VBF, VH, and gluon fusion) will be given.

  1. Search for the Higgs boson in fermionic channels using the ATLAS detector

    CERN Document Server

    Hanagaki, K; The ATLAS collaboration

    2013-01-01

    Since the discovery of a Higgs-like boson by the ATLAS and CMS experiments at the LHC, the emphasis has shifted towards measurements of its properties and the search in the less sensitive channels in order to determine whether the new particle is the Standard Model (SM) Higgs boson. Of particular importance is the direct observation of the coupling of the Higgs boson to tau-leptons, b-quarks and the top-quark. In this presentation a comprehensive review of ATLAS results in the search for the Higgs boson in tau-leptons, b-quark pair decay channel and in the VH and ttH will be given.

  2. Cosmic expansion from boson and fermion fields

    Energy Technology Data Exchange (ETDEWEB)

    De Souza, Rudinei C; Kremer, Gilberto M, E-mail: rudijantsch@gmail.com, E-mail: kremer@fisica.ufpr.br [Departamento de Fisica, Universidade Federal do Parana, Curitiba (Brazil)

    2011-06-21

    This paper consists in analyzing an action that describes boson and fermion fields minimally coupled to the gravity and a common matter field. The self-interaction potentials of the fields are not chosen a priori but from the Noether symmetry approach. The Noether forms of the potentials allow the boson field to play the role of dark energy and matter and the fermion field to behave as standard matter. The constant of motion and the cyclic variable associated with the Noether symmetry allow the complete integration of the field equations, whose solution produces a universe with alternated periods of accelerated and decelerated expansion.

  3. Cosmic expansion from boson and fermion fields

    CERN Document Server

    de Souza, Rudinei C

    2011-01-01

    This paper consists in analyzing an action that describes boson and fermion fields minimally coupled to the gravity and a common matter field. The self-interaction potentials of the fields are not chosen a priori but from the Noether symmetry approach. The Noether forms of the potentials allow the boson field to play the role of dark energy and matter and the fermion field to behave as standard matter. The constant of motion and the cyclic variable associated with the Noether symmetry allow the complete integration of the field equations, whose solution produces a Universe with alternated periods of accelerated and decelerated expansion.

  4. Cure from the cave: volcanic cave actinomycetes and their potential in drug discovery

    Directory of Open Access Journals (Sweden)

    Cheeptham N.

    2013-01-01

    Full Text Available Volcanic caves have been little studied for their potential as sources of novel microbial species and bioactive compounds with new scaffolds. We present the f irst study of volcanic cave microbiology from Canada and suggest that this habitat has great potential for the isolation of novel bioactive substances. Sample locat ions were plot ted on a contour map that was compiled in ArcView 3.2. Over 400 bacterial isolates were obtained from the Helmcken Falls cave in Wells Gray Provincial Park, British Columbia. From our preliminary screen, of 400 isolates tested, 1% showed activity against extended spectrum ß-lactamase E. coli, 1.75% against Escherichia coli, 2.25% against Acinetobacter baumannii, and 26.50% against Klebsiella pneumoniae. In addition, 10.25% showed activity against Micrococcus luteus, 2% against methicillin resistant Staphylococcus aureus, 9.25% against Mycobacterium smegmatis, 6.25% Pseudomonas aeruginosa and 7.5% against Candida albicans. Chemical and physical characteristics of three rock wall samples were studied using scanning electron microscopy and f lame atomic absorption spectrometry. Calcium (Ca, iron (Fe, and aluminum (Al were the most abundant components while magnesium (Mg, sodium (Na, arsenic (As, lead (Pb, chromium (Cr, and barium (Ba were second most abundant with cadmium (Cd and potassium (K were the least abundant in our samples. Scanning electron microscopy (SEM showed the presence of microscopic life forms in all three rock wall samples. 16S rRNA gene sequencing of 82 isolates revealed that 65 (79.3% of the strains belong to the Streptomyces genus and 5 (6.1% were members of Bacillus, Pseudomonas, Nocardia and Erwinia genera. Interestingly, twelve (14.6% of the 16S rRNA sequences showed similarity to unidentif ied ribosomal RNA sequences in the library databases, the sequences of these isolates need to be further investigated using the EzTaxon-e database (http://eztaxon-e. ezbiocloud.net/ to determine whether

  5. Direct search for the Standard Model Higgs boson

    Science.gov (United States)

    Janot, Patrick; Kado, Marumi

    2002-11-01

    For twelve years, LEP revolutionized the knowledge of electroweak symmetry breaking within the standard model, and the direct discovery of the Higgs boson would have been the crowning achievement. Searches at the Z resonance and above the W +W - threshold allowed an unambiguous lower limit on the mass of the standard model Higgs boson to set be at 114.1 GeV· c-2. After years of efforts to push the LEP performance far beyond the design limits, hints of what could be the first signs of the existence of a 115 GeV· c-2 Higgs boson appeared in June 2000, were confirmed in September, and were then confirmed again in November. An additional six-month period of LEP operation was enough to provide a definite answer, with an opportunity to make a fundamental discovery of prime importance. To cite this article: P. Janot, M. Kado, C. R. Physique 3 (2002) 1193-1202.

  6. Discovery potential for supernova relic neutrinos with slow liquid scintillator detectors

    CERN Document Server

    Wei, Hanyu; Chen, Shaomin

    2016-01-01

    The detection of supernova relic neutrinos would provide a key support for our current understanding of stellar and cosmological evolution, and precise measurements of them would further give us an insight of the profound universe. In this paper we study the potential to detect supernova relic neutrinos using linear alkyl benzene, LAB, as a slow liquid scintillator, which features a good separation of Cherenkov and scintillation lights, thus providing a new ability in particle identification. We also address key issues of current experiments, including 1) the charged current background of atmospheric neutrinos in water Cherenkov detectors, and 2) the neutral current background of atmospheric neutrinos in typical liquid scintillator detectors. With LAB, a kiloton-scale detector, like the SNO, KamLAND, and the future Jinping neutrino detectors, with $\\mathcal{O}$(10) years of data, would have the sensitivity to discover supernova relic neutrinos, which is comparable to large-volume water Cherenkov, typical liqu...

  7. Sumoylation in gene regulation and cardiac disease: potential for drug discovery

    Directory of Open Access Journals (Sweden)

    Beketaev I

    2014-11-01

    Full Text Available Ilimbek Beketaev, Jun Wang Center for Stem Cell Engineering, Department of Basic Research Laboratories, Texas Heart Institute at St Luke’s Episcopal Hospital, Houston, TX, USA Abstract: Small ubiquitin-related modifier (SUMO proteins are members of ubiquitin-like super-family proteins that can be covalently conjugated to their targets through multistep enzymatic reactions. Sumoylation has caught much attention due to its versatility, wide involvement in cellular events, and disease association. Sumoylation has been well studied at cellular and molecular levels. A newly emerging role that SUMO conjugation plays is in cardiac pathophysiology. In this review we will update new advances in the study of implications of the sumoylation pathway in the pathogenesis of cardiac diseases, discuss promise of the SUMO pathway as a potential therapeutic target, and conclude with future directions for SUMO research in the heart field. Keywords: posttranslational modification, SUMO, SENP, heart

  8. Discovery of dihydrochalcone as potential lead for Alzheimer's disease: in silico and in vitro study.

    Directory of Open Access Journals (Sweden)

    Man Hoang Viet

    Full Text Available By the virtual screening method we have screened out Dihydrochalcone as a top-lead for the Alzheimer's disease using the database of about 32364 natural compounds. The binding affinity of this ligand to amyloid beta (Aβ fibril has been thoroughly studied by computer simulation and experiment. Using the Thioflavin T (ThT assay we have obtained the inhibition constant IC50 μM. This result is in good agreement with the estimation of the binding free energy obtained by the molecular mechanic-Poisson Boltzmann surface area method and all-atom simulation with the force field CHARMM 27 and water model TIP3P. Cell viability assays indicated that Dihydrochalcone could effectively reduce the cytotoxicity induced by Aβ. Thus, both in silico and in vitro studies show that Dihydrochalcone is a potential drug for the Alzheimers disease.

  9. Commissioning of the ATLAS electromagnetic calorimeter and Z' {yields} e{sup +}e{sup -} discovery potential in the first LHC data; Mise en service du calorimetre electromagnetique d'Atlas et determination du potentiel de decouverte d'un Z' {yields} e{sup +}e{sup -} dans les premieres donnees LHC

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2009-07-15

    After about fifteen years of development, the ATLAS detector is ready to operate and it recorded, in 2008, several millions of cosmic events as well as first LHC data. This achievement is based on the long experience of beam tests and on the large effort towards the detector in situ commissioning undertaken by the ATLAS collaboration. This promises fast ability to perform searches for evidence of the Higgs boson and new physics. I heavily contributed to the in situ commissioning of the electromagnetic calorimeter. To verify its performance, I studied the first cosmic data taken in 2006 which allowed the first in situ analysis of dead channels, energy reconstruction and detector response uniformity. This participation to the commissioning has continued with the study of the single beam data recorded during the first week of LHC operation (Sept. 2008). Expanding on my expertise of the electromagnetic calorimeter, I focused my physics analysis, prepared with simulation, on the promising discovery potential of new physics at LHC via the di-electron/di-photon decay of new heavy gauge boson in the early LHC data (the first 100 pb{sup -1}). Possible limitations coming from early hardware problems or imperfect electron energy calibration in first data have been estimated. According to the new schedule of LHC operation, this analysis will be possible with 10 TeV pp collisions data in 2010. (author)

  10. A potential source for cellulolytic enzyme discovery and environmental aspects revealed through metagenomics of Brazilian mangroves.

    Science.gov (United States)

    Thompson, Claudia Elizabeth; Beys-da-Silva, Walter Orlando; Santi, Lucélia; Berger, Markus; Vainstein, Marilene Henning; Guima Rães, Jorge Almeida; Vasconcelos, Ana Tereza Ribeiro

    2013-01-01

    The mangroves are among the most productive and biologically important environments. The possible presence of cellulolytic enzymes and microorganisms useful for biomass degradation as well as taxonomic and functional aspects of two Brazilian mangroves were evaluated using cultivation and metagenomic approaches. From a total of 296 microorganisms with visual differences in colony morphology and growth (including bacteria, yeast and filamentous fungus), 179 (60.5%) and 117 (39.5%) were isolated from the Rio de Janeiro (RJ) and Bahia (BA) samples, respectively. RJ metagenome showed the higher number of microbial isolates, which is consistent with its most conserved state and higher diversity. The metagenomic sequencing data showed similar predominant bacterial phyla in the BA and RJ mangroves with an abundance of Proteobacteria (57.8% and 44.6%), Firmicutes (11% and 12.3%) and Actinobacteria (8.4% and 7.5%). A higher number of enzymes involved in the degradation of polycyclic aromatic compounds were found in the BA mangrove. Specific sequences involved in the cellulolytic degradation, belonging to cellulases, hemicellulases, carbohydrate binding domains, dockerins and cohesins were identified, and it was possible to isolate cultivable fungi and bacteria related to biomass decomposition and with potential applications for the production of biofuels. These results showed that the mangroves possess all fundamental molecular tools required for building the cellulosome, which is required for the efficient degradation of cellulose material and sugar release.

  11. Search for the Higgs Boson in the Channel H->ZZ*->4l with the ATLAS Detector

    CERN Document Server

    Rebuzzi, D; The ATLAS collaboration

    2009-01-01

    The decay channel H->ZZ*->4l provides a clean signature for the Higgs boson in the mass range between ~120 GeV and 2MZ, above which the "gold-plated" channel with two real Z bosons in the final state opens up. The signal cross section is several orders of magnitude smaller than those for the backgrounds, therefore a thorough understanding of the multi-lepton processes is needed to obtain a high background rejection. Crucial for this channel is also a very good knowledge of the trigger and detector response for lepton identification and reconstruction. The observability of the signal on top of the reducible tt, Zbb and of the irreducible ZZz backgrounds with the ATLAS Detector is discussed in the following, with particular emphasis on lepton reconstruction. The ATLAS discovery potential for the H->4l, including the most realistic and up-to-date description of the detector performance, is presented.

  12. Higgs boson theory and phenomenology mass measurements and nuclear physics Recent results from ISOLTRAP

    CERN Document Server

    Carena, M S; Herfurth, F; Ames, F; Audi, G; Beck, D; Blaum, K; Bollen, G; Kellerbauer, A G; Kluge, H J; Kuckein, M; Lunney, M D; Moore, R B; Oinonen, M; Rodríguez, D; Sauvan, E; Scheidenberger, C

    2003-01-01

    Precision electroweak data presently-favors a weakly-coupled Higgs sector as the mechanism responsible for electroweak symmetry breaking. Low-energy supersymmetry provides a natural framework for weakly-coupled elementary scalars. In this review, we summarize the theoretical properties of the Standard Model (SM) Higgs boson and the Higgs sector of the minimal super-symmetric extension of the Standard Model (MSSM). We then survey the phenomenology of the SM and MSSM Higgs bosons at the Tevatron, LHC and a future e**+e**- linear collider. We focus on the Higgs discovery potential of present and future colliders and stress the importance of precision measurements of Higgs boson properties. 459 Refs.31 The Penning trap mass spectrometer ISOLTRAP is a facility for high- precision mass measurements of short-lived radioactive nuclei installed at ISOLDE/CERN in Geneva. More than 200 masses have been measured with relative uncertainties of 1 multiplied by 10**-**7 or even close to 1 multiplied by 10**-**8 in special c...

  13. Searching for new heavy neutral gauge bosons using vector boson fusion processes at the LHC

    Science.gov (United States)

    Flórez, Andrés; Gurrola, Alfredo; Johns, Will; Oh, Young Do; Sheldon, Paul; Teague, Dylan; Weiler, Thomas

    2017-04-01

    New massive resonances are predicted in many extensions to the Standard Model (SM) of particle physics and constitutes one of the most promising searches for new physics at the LHC. We present a feasibility study to search for new heavy neutral gauge bosons using vector boson fusion (VBF) processes, which become especially important as the LHC probes higher collision energies. In particular, we consider the possibility that the discovery of a Z‧ boson may have eluded searches at the LHC. The coupling of the Z‧ boson to the SM quarks can be small, and thus the Z‧ would not be discoverable by the searches conducted thus far. In the context of a simplified phenomenological approach, we consider the Z‧ → ττ and Z‧ → μμ decay modes to show that the requirement of a dilepton pair combined with two high pT forward jets with large separation in pseudorapidity and with large dijet mass is effective in reducing SM backgrounds. The expected exclusion bounds (at 95% confidence level) are m (Z‧) < 1.8 TeV and m (Z‧) < 2.5 TeV in the ττjfjf and μμjfjf channels, respectively, assuming 1000 fb-1 of 13 TeV data from the LHC. The use of the VBF topology to search for massive neutral gauge bosons provides a discovery reach with expected significances greater than 5σ (3σ) for Z‧ masses up to 1.4 (1.6) TeV and 2.0 (2.2) TeV in the ττjfjf and μμjfjf channels.

  14. Looking For Physics Beyond The Standard Model: Searches For Charged Higgs Bosons At $e^{+}e^{-}$ Colliders

    CERN Document Server

    Kiiskinen, A P

    2004-01-01

    This thesis describes direct searches for pair production of charged Higgs bosons performed in the data collected by the DELPHI detector at the LEP collider at CERN. In addition, the possibilities to discover and study heavy charged Higgs bosons at possible future high-energy linear colliders are presented. The existence of charged Higgs bosons is predicted by many extensions of the Standard Model. A possible discovery of these particles would be a solid proof for physics beyond the Standard Model. Discovery of charged Higgs bosons, and measurement of their properties, would also provide useful information about the structure of the more general theory. New analysis methods were developed for the searches performed at LEP. A large, previously unexplored, mass range for cover but no evidence for the existence of the charged Higgs bosons was found. This allowed setting new lower mass limits for the charged Higgs boson within the framework of general two Higgs doublet models. Results have been interpreted and pr...

  15. Discovery of a New Class of Cathepsin K Inhibitors in Rhizoma Drynariae as Potential Candidates for the Treatment of Osteoporosis

    Science.gov (United States)

    Qiu, Zuo-Cheng; Dong, Xiao-Li; Dai, Yi; Xiao, Gao-Keng; Wang, Xin-Luan; Wong, Ka-Chun; Wong, Man-Sau; Yao, Xin-Sheng

    2016-01-01

    Rhizoma Drynariae (RD), as one of the most common clinically used folk medicines, has been reported to exert potent anti-osteoporotic activity. The bioactive ingredients and mechanisms that account for its bone protective effects are under active investigation. Here we adopt a novel in silico target fishing method to reveal the target profile of RD. Cathepsin K (Ctsk) is one of the cysteine proteases that is over-expressed in osteoclasts and accounts for the increase in bone resorption in metabolic bone disorders such as postmenopausal osteoporosis. It has been the focus of target based drug discovery in recent years. We have identified two components in RD, Kushennol F and Sophoraflavanone G, that can potentially interact with Ctsk. Biological studies were performed to verify the effects of these compounds on Ctsk and its related bone resorption process, which include the use of in vitro fluorescence-based Ctsk enzyme assay, bone resorption pit formation assay, as well as Receptor Activator of Nuclear factor κB (NF-κB) ligand (RANKL)-induced osteoclastogenesis using murine RAW264.7 cells. Finally, the binding mode and stability of these two compounds that interact with Ctsk were determined by molecular docking and dynamics methods. The results showed that the in silico target fishing method could successfully identify two components from RD that show inhibitory effects on the bone resorption process related to protease Ctsk. PMID:27999266

  16. Reheating with a composite Higgs boson

    Science.gov (United States)

    Croon, Djuna; Sanz, Verónica; Tarrant, Ewan R. M.

    2016-08-01

    The flatness of the inflaton potential and lightness of the Higgs boson could have the common origin of the breaking of a global symmetry. This scenario provides a unified framework of Goldstone inflation and composite Higgs models, where the inflaton and the Higgs particle both have a pseudo-Goldstone boson nature. The inflaton reheats the Universe via decays to the Higgs and subsequent secondzary production of other SM particles via the top and massive vector bosons. We find that inflationary predictions and perturbative reheating conditions are consistent with cosmic microwave background data for sub-Planckian values of the fields, as well as opening up the possibility of inflation at the TeV scale. We explore this exciting possibility, leading to an interplay between collider data cosmological constraints.

  17. Boson/Fermion Janus Particles

    CERN Document Server

    Tsekov, R

    2016-01-01

    Thermodynamically, bosons and fermions differ by their statistics only. A general entropy functional is proposed by superposition of entropic terms, typical for different quantum gases. The statistical properties of the corresponding Janus particles are derived by variation of the weight of the boson/fermion fraction. It is shown that di-bosons and anti-fermions separate in gas and liquid phases, while three-phase equilibrium appears for poly-boson/fermion Janus particles.

  18. Dynamical Boson Stars

    Directory of Open Access Journals (Sweden)

    Steven L. Liebling

    2012-05-01

    Full Text Available The idea of stable, localized bundles of energy has strong appeal as a model for particles. In the 1950s, John Wheeler envisioned such bundles as smooth configurations of electromagnetic energy that he called geons, but none were found. Instead, particle-like solutions were found in the late 1960s with the addition of a scalar field, and these were given the name boson stars. Since then, boson stars find use in a wide variety of models as sources of dark matter, as black hole mimickers, in simple models of binary systems, and as a tool in finding black holes in higher dimensions with only a single Killing vector. We discuss important varieties of boson stars, their dynamic properties, and some of their uses, concentrating on recent efforts.

  19. Finding the Higgs Boson through Supersymmetry

    CERN Document Server

    De Campos, F; Magro, M B; Restrepo, D; Valle, J W F

    2008-01-01

    The study of displaced vertices containing two b--jets may provide a double discovery at the Large Hadron Collider (LHC): we show how it may not only reveal evidence for supersymmetry, but also provide a way to uncover the Higgs boson necessary in the formulation of the electroweak theory in a large region of the parameter space. We quantify this explicitly using the simplest minimal supergravity model with bilinear breaking of R-parity, which accounts for the observed pattern of neutrino masses and mixings seen in neutrino oscillation experiments.

  20. Quantization over boson operator spaces

    Energy Technology Data Exchange (ETDEWEB)

    Prosen, Tomaz [Department of Physics, FMF, University of Ljubljana, Ljubljana (Slovenia); Seligman, Thomas H [Instituto de Ciencias FIsicas, Universidad Nacional Autonoma de Mexico, Cuernavaca, Morelos (Mexico)

    2010-10-01

    The framework of third quantization-canonical quantization in the Liouville space-is developed for open many-body bosonic systems. We show how to diagonalize the quantum Liouvillean for an arbitrary quadratic n-boson Hamiltonian with arbitrary linear Lindblad couplings to the baths and, as an example, explicitly work out a general case of a single boson. (fast track communication)

  1. Quantization over boson operator spaces

    CERN Document Server

    Prosen, Tomaz

    2010-01-01

    The framework of third quantization - canonical quantization in the Liouville space - is developed for open many-body bosonic systems. We show how to diagonalize the quantum Liouvillean for an arbitrary quadratic n-boson Hamiltonian with arbitrary linear Lindblad couplings to the baths and, as an example, explicitly work out a general case of a single boson.

  2. Higgs boson and inflation

    Directory of Open Access Journals (Sweden)

    FENG Chaojun

    2014-08-01

    Full Text Available Higgs is the only scalar particle that already observed up to now.In the standard model of particle physics,Higgs plays a very important role.On the other hand,inflation is also driven by scalar field called inflaton.Higgs boson can not be the inflaton since the large hierarchy energy scale of the mass between inflaton and itself.However,by using some indirectly method,inflaton could be another aspect of the Higgs boson.In this paper,the authors review some Higgs inflation models and discuss the role of the cosmological constant during inflation.

  3. Search for the Standard Model Higgs boson in the $H\\rightarrow W^{+}W^{-}\\rightarrow\\ell^{+}\

    CERN Document Server

    Schmidt, Evelyn

    2013-06-06

    Modern particle physics research is dedicated to study the fundamental constituents of matter and their interactions. Scientific research findings on both theoretical and experimental sides during the past decades have been condensed in the Standard Model of particle physics. In this model, the interactions between fundamental particles are described by gauge fields and the exchange of corresponding gauge bosons. The Standard Model contains several such bosons, for example the massive and charged W bosons and a neutral Z boson, that have been observed experimentally. The simplest and most popular implementation of electroweak symmetry breaking to attribute mass to the W and Z bosons is the Higgs mechanism. This mechanism implies the existence of one additional particle, the Higgs boson, that is the only remaining particle of the Standard Model to be established experimentally. In July 2012, the discovery of a new neutral boson with a measured mass of about 126 GeV was announced by the ATLAS and CMS collaborat...

  4. Charged Higgs boson in the W± Higgs channel at the Large Hadron Collider

    Directory of Open Access Journals (Sweden)

    Rikard Enberg

    2015-04-01

    Full Text Available In light of the recent discovery of a neutral Higgs boson, Hobs, with a mass near 125 GeV, we reassess the LHC discovery potential of a charged Higgs boson, H±, in the W±Hobs decay channel. This decay channel can be particularly important for a H± heavier than the top quark, when it is produced through the pp→tH± process. The knowledge of the mass of Hobs provides an additional handle in the kinematic selection when reconstructing a Breit–Wigner resonance in the Hobs→bb¯ decay channel. We consider some extensions of the Standard Model Higgs sector, with and without supersymmetry, and perform a dedicated signal-to-background analysis to test the scope of this channel for the LHC running at the design energy (14 TeV, for 300 fb−1 (standard and 3000 fb−1 (high integrated luminosities. We find that, while this channel does not show much promise for a supersymmetric H± state, significant portions of the parameter spaces of several two-Higgs doublet models are testable.

  5. Light sgoldstino's interactions analysis and prospects for potential discovery in electron beam dump experiment at CERN SPS

    OpenAIRE

    Astapov, K. O.; Kirpichnikov, D. V.

    2016-01-01

    In the present paper we have discussed light sgoldstino in context of MSSM model. We have analyzed couplings of scalar sgoldstino to SM particles, namely to photons, $Z^0$ bosons, leptons and quarks. We also took into account the impact on those interactions of the admixture of lightest MSSM Higgs scalar in the sgoldstino state. The signal rate of rare decays at CERN electron beam dump experiment NA64 for the scalar sgoldstino has been estimated. Expected signal rate allowed us to exclude som...

  6. Higgs boson: the winner takes it all?

    CERN Multimedia

    Antonella Del Rosso

    2015-01-01

    Since its discovery in 2012, the Higgs boson has been in the spotlight for both experimentalists and theorists. In addition to its confirmed role in the mass mechanism, recent papers have discussed its possible role in the inflation of the universe and in the matter-antimatter imbalance. Can a single particle be responsible for everything?   “Since 2012 we have known that the Higgs boson exists, but its inner properties are yet to be completely uncovered,” says Gian Giudice, a member of the CERN Theory Unit. “Precise measurements of its decay modes are still ongoing and the LHC Run 2 will be essential to understand the nature of this particle at a deeper level.” What we know is that this boson is not “yet another particle” among the hundreds that we deal with every day in physics labs. In agreement with the Standard Model theory, the recent experimental data confirms that the particle discovered by the CERN experiments is the key pa...

  7. Z Bosons in LHCb

    CERN Document Server

    AUTHOR|(CDS)2077480; Müller, Katharina; Anderson, Jonathan

    In this thesis several measurements of the $Z$ boson production cross section in the LHCb detector are presented. After an introduction with the description of the underlying theory; the detector and the properties of the collisions the machine provided to us in LHC run I in Chapter 1, in Chapter 2 the details of the $Z$ reconstruction in the $Z\\rightarrow\\mu^+\\mu^-$ final state is discussed. In Chapter 3 jets are added to the $Z$ bosons. Several aspects of jet reconstruction are presented and a cross section measurement for the associated production of $Z$ bosons with jets at $\\sqrt{s}=7$ TeV is presented for two transverse momentum thresholds of the jets. In Chapter 4 the capability of the LHCb detector to reconstruct charmed mesons is used to establish a $ZD^{0}$ and a $ZD^{+}$ signal and to measure the total cross section. In Chapter 5 the cross section of inclusive $Z$ boson production is measured at a low statistics sample of $3.3~\\text{pb}^{-1}$ at $\\sqrt{s}=2.76$ TeV.

  8. BEH Boson (CMS)

    CERN Document Server

    Checchia, Paolo

    2016-01-01

    The most relevant results on Higgs sector from CMS are presented. The status of the measurements of the Higgs Boson properties after the complete analysis of Run I dataset and an overview of the results obtained with the limited luminosity delivered at 13 TeV in 2015 are given. Implications of the results and future perspectives are also briefly discussed.

  9. Higgs boson mass and new physics

    Energy Technology Data Exchange (ETDEWEB)

    Bezrukov, Fedor [Connecticut Univ., Storrs, CT (United States). Dept. of Physics; Brookhaven National Lab., Upton, NY (United States). RIKEN-BNL Research Center; Kalmykov, Mikhail Yu.; Kniehl, Bernd A. [Hamburg Univ. (Germany). 2. Inst. fuer Theoretische Physik; Shaposhnikov, Mikhail [Ecole Polytechnique Federale de Lausanne (Switzerland). Inst. de Theorie des Phenomenes Physiques

    2012-05-15

    We discuss the lower Higgs boson mass bounds which come from the absolute stability of the Standard Model (SM) vacuum and from the Higgs inflation, as well as the prediction of the Higgs boson mass coming from asymptotic safety of the SM. We account for the 3-loop renormalization group evolution of the couplings of the Standard Model and for a part of two-loop corrections that involve the QCD coupling {alpha}{sub s} to initial conditions for their running. This is one step above the current state of the art procedure (''one-loop matching-two-loop running''). This results in reduction of the theoretical uncertainties in the Higgs boson mass bounds and predictions, associated with the Standard Model physics, to 1-2 GeV. We find that with the account of existing experimental uncertainties in the mass of the top quark and {alpha}{sub s} (taken at 2{sigma} level) the bound reads M{sub H} {>=} M{sub min} (equality corresponds to the asymptotic safety prediction), where M{sub min}=129{+-}6 GeV. We argue that the discovery of the SM Higgs boson in this range would be in agreement with the hypothesis of the absence of new energy scales between the Fermi and Planck scales, whereas the coincidence of M{sub H} with M{sub min} would suggest that the electroweak scale is determined by Planck physics. In order to clarify the relation between the Fermi and Planck scale a construction of an electron-positron or muon collider with a center of mass energy {proportional_to}200+200 GeV (Higgs and t-quark factory) would be needed.

  10. Higgs Bosons in Extra Dimensions

    CERN Document Server

    Quiros, Mariano

    2015-01-01

    In this paper, motivated by the recent discovery of a Higgs-like boson at the LHC with a mass m_H\\simeq 126 GeV, we review different models where the hierarchy problem is solved by means of a warped extra dimension. In the Randall-Sundrum model electroweak observables provide very strong bounds on the mass of KK modes which motivates extensions to overcome this problem. Two extensions are briefly discussed. One particular extension is based on the deformation of the metric such that it strongly departs from the AdS_5 structure in the IR region while it goes asymptotically to AdS_5 in the UV brane. This model has the IR brane close to a naked metric singularity (which is outside the physical interval) characteristic of soft-walls constructions. The proximity of the singularity provides a strong wave-function renormalization for the Higgs field which suppresses the T and S parameters. The second class of considered extensions are based on the introduction of an extra gauge group in the bulk such that the custod...

  11. Creating the Fermion Mass Hierarchies with Multiple Higgs Bosons

    Energy Technology Data Exchange (ETDEWEB)

    Bauer, Martin [U. Heidelberg, ITP; Carena, Marcela [Chicago U., KICP; Gemmler, Katrin [TUM-IAS, Munich

    2015-12-10

    After the Higgs boson discovery, it is established that the Higgs mechanism explains electroweak symmetry breaking and generates the masses of all particles in the Standard Model, with the possible exception of neutrino masses. The hierarchies among fermion masses and mixing angles remain however unexplained. We propose a new class of two Higgs doublet models in which a flavor symmetry broken at the electroweak scale addresses this problem. The models are strongly constrained by electroweak precision tests and the fact that they produce modifications to Higgs couplings and flavor changing neutral currents; they are also constrained by collider searches for extra scalar bosons. The surviving models are very predictive, implying unavoidable new physics signals at the CERN Large Hadron Collider, e.g. extra Higgs Bosons with masses $M < 700$ GeV.

  12. Creating the Fermion Mass Hierarchies with Multiple Higgs Bosons

    CERN Document Server

    Bauer, Martin; Gemmler, Katrin

    2015-01-01

    After the Higgs boson discovery, it is established that the Higgs mechanism explains electroweak symmetry breaking and generates the masses of all particles in the Standard Model, with the possible exception of neutrino masses. The hierarchies among fermion masses and mixing angles remain however unexplained. We propose a new class of two Higgs doublet models in which a flavor symmetry broken at the electroweak scale addresses this problem. The models are strongly constrained by electroweak precision tests and the fact that they produce modifications to Higgs couplings and flavor changing neutral currents; they are also constrained by collider searches for extra scalar bosons. The surviving models are very predictive, implying unavoidable new physics signals at the CERN Large Hadron Collider, e.g. extra Higgs Bosons with masses $M < 700$ GeV.

  13. Creating the fermion mass hierarchies with multiple Higgs bosons

    Science.gov (United States)

    Bauer, Martin; Carena, Marcela; Gemmler, Katrin

    2016-12-01

    After the Higgs boson discovery, it was established that the Higgs mechanism explains electroweak symmetry breaking and generates the masses of all particles in the Standard Model, with the possible exception of neutrino masses. The hierarchies among fermion masses and mixing angles, however, remain unexplained. We propose a new class of two Higgs doublet models in which a flavor symmetry broken at the electroweak scale addresses this problem. The models are strongly constrained by electroweak precision tests and the fact that they produce modifications to Higgs couplings and flavor-changing neutral currents; they are also constrained by collider searches for extra scalar bosons. The surviving models are very predictive, implying unavoidable new physics signals at the CERN Large Hadron Collider, e.g., extra Higgs bosons with masses M <700 GeV .

  14. Measurement of the Jet Momentum Resolution and Search for a light Standard Model Higgs Boson in the H(bb)W(lv) Channel with the CMS Detector at the LHC

    CERN Document Server

    Held, Hauke

    The Higgs boson is the last particle predicted by the Standard Model which remains undetected. Its potential discovery was a main objective of the construction of the Large Hadron Collider (LHC) at CERN. Its exclusion would necessitate the existence of new physics beyond the Standard Model. A search for the Higgs boson decaying into two bottom quarks in association with the production of a leptonically decaying W boson is presented based on pp collision data recorded with the CMS experiment in 2011, corresponding to an integrated luminosity of L = 4.65 fb−1. Events are selected requiring the presence of an isolated charged lepton (electron or muon), missing transverse energy and two b-jets, which are clustered with the anti-kT jet algorithm at first. The search is performed in a boosted event topology, where both the W boson and the Higgs boson candidates have high momenta and move back-to-back in the transverse detector plane. Artificial Neural Networks are employed to discriminate signal and background ev...

  15. Repelling Point Bosons

    Science.gov (United States)

    McGuire, J. B.

    2011-12-01

    There is a body of conventional wisdom that holds that a solvable quantum problem, by virtue of its solvability, is pathological and thus irrelevant. It has been difficult to refute this view owing to the paucity of theoretical constructs and experimental results. Recent experiments involving equivalent ions trapped in a spatial conformation of extreme anisotropic confinement (longitudinal extension tens, hundreds or even thousands of times transverse extension) have modified the view of relevancy, and it is now possible to consider systems previously thought pathological, in particular point Bosons that repel in one dimension. It has been difficult for the experimentalists to utilize existing theory, mainly due to long-standing theoretical misunderstanding of the relevance of the permutation group, in particular the non-commutativity of translations (periodicity) and transpositions (permutation). This misunderstanding is most easily rectified in the case of repelling Bosons.

  16. Experimental Boson Sampling

    CERN Document Server

    Spring, Justin B; Humphreys, Peter C; Kolthammer, W Steven; Jin, Xian-Min; Barbieri, Marco; Datta, Animesh; Thomas-Peter, Nicholas; Langford, Nathan K; Kundys, Dmytro; Gates, James C; Smith, Brian J; Smith, Peter G R; Walmsley, Ian A

    2013-01-01

    While universal quantum computers ideally solve problems such as factoring integers exponentially more efficiently than classical machines, the formidable challenges in building such devices motivate the demonstration of simpler, problem-specific algorithms that still promise a quantum speedup. We construct a quantum boson sampling machine (QBSM) to sample the output distribution resulting from the nonclassical interference of photons in an integrated photonic circuit, a problem thought to be exponentially hard to solve classically. Unlike universal quantum computation, boson sampling merely requires indistinguishable photons, linear state evolution, and detectors. We benchmark our QBSM with three and four photons and analyze sources of sampling inaccuracy. Our studies pave the way to larger devices that could offer the first definitive quantum-enhanced computation.

  17. On the origins and the historical roots of the Higgs boson research from a bibliometric perspective

    CERN Document Server

    Barth, Andreas; Bornmann, Lutz; Mutz, Ruediger

    2014-01-01

    Subject of our present paper is the analysis of the origins or historical roots of the Higgs boson research from a bibliometric perspective, using a segmented regression analysis in a reference publication year spectroscopy (RPYS). Our analysis is based on the references cited in the Higgs boson publications published since 1974. The objective of our analysis consists of identifying concrete individual publications in the Higgs boson research context to which the scientific community frequently had referred to. As a consequence, we are interested in seminal works which contributed to a high extent to the discovery of the Higgs boson. Our results show that researchers in the Higgs boson field preferably refer to more recently published papers - particular papers published since the beginning of the sixties. For example, our analysis reveals seven major contributions which appeared within the sixties: Englert and Brout (1964), Higgs (1964, 2 papers), and Guralnik et al. (1964) on the Higgs mechanism as well as ...

  18. Search for a Higgs boson in fermion decay modes at the LHC

    CERN Document Server

    Alonso, A; The ATLAS collaboration

    2013-01-01

    Since the discovery of a Higgs-like boson by the ATLAS and CMS experiments at the LHC, the emphasis has shifted towards measurements of its properties in order to determine whether the new particle is the Standard Model (SM) Higgs boson, or not. Of particular importance is the direct observation of the coupling of the Higgs boson to fermions and rare decay modes. In this presentation a comprehensive review of ATLAS and CMS results in the search for the Higgs boson in the main fermion decay (bb and tautau) channels and in various production modes (VBF, VH, and gluon fusion) and in the searches for the SM Higgs boson via decays in rare modes such as dimuon pairs or invisible decays.

  19. Search for the Higgs boson in VH(H➞bb) and in the H➞

    CERN Document Server

    Gonzalez Parra, Garoe; The ATLAS collaboration

    2013-01-01

    Since the discovery of a Higgs-like boson by the ATLAS and CMS experiments at the LHC, the emphasis has shifted towards measurements of its properties and the search for the search in the less sensitive channels in order to determine whether the new particle is the Standard Model (SM) Higgs boson. Of particular importance is the direct observation of the coupling of the Higgs boson to b-quarks, the top-quark and leptons. In this presentation a comprehensive review of ATLAS results in the search for the Higgs boson in b-quark pair decay channel and in the VH and ttH will be given. A comprehensive review of ATLAS results in the search for the Higgs boson in the tau-tau decay channel and in various production modes will be also given.

  20. Measuring the trilinear neutral Higgs boson couplings in the MSSM at $e^+ e^-$ colliders

    CERN Document Server

    Khosa, Charanjit K

    2016-01-01

    We consider the measurement of the trilinear couplings of the neutral Higgs bosons~($H^0, h^0$) in the minimal supersymmetric standard model~(MSSM) at a high energy $e^+$ $e^-$ linear collider in the light of the discovery of a Higgs boson at the CERN Large Hadron Collider~(LHC). We identify the state observed at the LHC with the lightest CP-even Higgs boson of the MSSM. We implement this constraint, as well as all the other relevant experimental constraints, on the parameter space of the MSSM in order to study the feasibility of measuring the trilinear couplings of the neutral Higgs bosons. For the measurement of trilinear couplings, we consider the multiple Higgs production processes. We delineate the regions of MSSM parameter space where the trilinear couplings of the neutral Higgs bosons could be measured at a high energy electron-positron collider.

  1. Higgs Boson Properties

    CERN Document Server

    David, André

    2016-01-01

    This chapter presents an overview of the measured properties of the Higgs boson discovered in 2012 by the ATLAS and CMS collaborations at the CERN LHC. Searches for deviations from the properties predicted by the standard theory are also summarised. The present status corresponds to the combined analysis of the full Run 1 data sets of collisions collected at centre-of-mass energies of 7 and 8 TeV.

  2. Higgs Boson Properties

    Science.gov (United States)

    David, André Dührssen, Michael

    2016-10-01

    This chapter presents an overview of the measured properties of the Higgs boson discovered in 2012 by the ATLAS and CMS collaborations at the CERN LHC. Searches for deviations from the properties predicted by the standard theory are also summarised. The present status corresponds to the combined analysis of the full Run 1 data sets of collisions collected at centre-of-mass energies of 7 and 8 TeV.

  3. New decay modes of heavy Higgs bosons in a two Higgs doublet model with vectorlike leptons

    CERN Document Server

    Dermisek, Radovan; Shin, Seodong

    2015-01-01

    In models with extended Higgs sector and additional matter fields, the decay modes of heavy Higgs bosons can be dominated by cascade decays through the new fermions rendering present search strategies ineffective. We investigate new decay topologies of heavy neutral Higgses in two Higgs doublet model with vectorlike leptons. We also discuss constraints from existing searches and discovery prospects. Among the most interesting signatures are monojet, mono Z, mono Higgs, and Z and Higgs bosons produced with a pair of charged leptons.

  4. Higgs Boson Mass and Complex Snuetrino Dark Matter in the Supersymmetric Inverse Seesaw Models

    CERN Document Server

    Guo, Jun; Li, Tianjun; Liu, Yandong

    2014-01-01

    The discovery of a relatively heavy Standard Model (SM) -like Higgs boson challenges naturalness of the minimal supersymmetric standard model (MSSM) from both Higgs and dark matter (DM) sectors. We study these two aspects in the MSSM extended by the low-scale inverse seesaw mechanism. Firstly, it admits a sizable radiative correction on the Higgs boson mass m_h, up to \\sim 4 GeV in the case of an IR-fixed point of the coupling Y_\

  5. Inclusive Higgs boson and dijet production via Double Pomeron exchange

    CERN Document Server

    Boonekamp, M; Royon, C

    2001-01-01

    We evaluate Higgs boson and dijet cross-sections at the Tevatron collider via Double Pomeron exchange when accompanying particles in the central region are taken into account. Such {\\it inclusive} processes, normalized to the observed dijet rate observed at run I, noticeably increase the predictions for tagged (anti)protons in the run II with respect to {\\it exclusive} ones, with the potentiality of Higgs boson detection.

  6. Experimental search of Higgs boson; Busqueda experimental del boson de Higgs

    Energy Technology Data Exchange (ETDEWEB)

    Alcarz Maestre, J.; Josa Mutuberria, M. I.

    2000-07-01

    After an introduction to the relevance and intrinsic properties of the Higgs particle, we discuss some aspects related to the search for the Higgs boson at the LEP e''+ e''- collider. This year 2000 is the last year of data taking for the LEP programme, at the largest energies ever reached in e''+ e''- collisions in laboratory. This offers a unique opportunity to extend the reach of current searches and to observe the Higgs. Prospects for a Higgs discovery beyond LEP are also briefly discussed. (Author) 6 refs.

  7. Z'-gauge Bosons as Harbingers of Low Mass Strings

    CERN Document Server

    Anchordoqui, Luis A; Goldberg, Haim; Huang, Xing; Lüst, Dieter; Taylor, Tomasz R

    2012-01-01

    Massive Z'-gauge bosons act as excellent harbingers for string compactifications with a low string scale. In D-brane models they are associated to U(1) gauge symmetries that are either anomalous in four dimensions or exhibit a hidden higher dimensional anomaly. We discuss the possible signals of massive Z'-gauge bosons at hadron collider machines (Tevatron, LHC) in a minimal D-brane model consisting out of four stacks of D-branes. In this construction, there are two massive gauge bosons, which can be naturally associated with baryon number B and B-L (L being lepton number). Here baryon number is always anomalous in four dimensions, whereas the presence of a four-dimensional B-L anomaly depends on the U(1)-charges of the right handed neutrinos. In case B-L is anomaly free, a mass hierarchy between the two associated Z'-gauge bosons can be explained. In our phenomenological discussion about the possible discovery of massive Z'-gauge bosons, we take as a benchmark scenario the dijet plus W signal, recently obser...

  8. Evaluating the potential of a novel oral lesion exudate collection method coupled with mass spectrometry-based proteomics for oral cancer biomarker discovery

    Directory of Open Access Journals (Sweden)

    Kooren Joel A

    2011-09-01

    Full Text Available Abstract Introduction Early diagnosis of Oral Squamous Cell Carcinoma (OSCC increases the survival rate of oral cancer. For early diagnosis, molecular biomarkers contained in samples collected non-invasively and directly from at-risk oral premalignant lesions (OPMLs would be ideal. Methods In this pilot study we evaluated the potential of a novel method using commercial PerioPaper absorbent strips for non-invasive collection of oral lesion exudate material coupled with mass spectrometry-based proteomics for oral cancer biomarker discovery. Results Our evaluation focused on three core issues. First, using an "on-strip" processing method, we found that protein can be isolated from exudate samples in amounts compatible with large-scale mass spectrometry-based proteomic analysis. Second, we found that the OPML exudate proteome was distinct from that of whole saliva, while being similar to the OPML epithelial cell proteome, demonstrating the fidelity of our exudate collection method. Third, in a proof-of-principle study, we identified numerous, inflammation-associated proteins showing an expected increase in abundance in OPML exudates compared to healthy oral tissue exudates. These results demonstrate the feasibility of identifying differentially abundant proteins from exudate samples, which is essential for biomarker discovery studies. Conclusions Collectively, our findings demonstrate that our exudate collection method coupled with mass spectrometry-based proteomics has great potential for transforming OSCC biomarker discovery and clinical diagnostics assay development.

  9. Integrative Genomic Data Mining for Discovery of Potential Blood-Borne Biomarkers for Early Diagnosis of Cancer

    OpenAIRE

    Yongliang Yang; Pavel Pospisil; Iyer, Lakshmanan K.; S. James Adelstein; Amin I. Kassis

    2008-01-01

    BACKGROUND: With the arrival of the postgenomic era, there is increasing interest in the discovery of biomarkers for the accurate diagnosis, prognosis, and early detection of cancer. Blood-borne cancer markers are favored by clinicians, because blood samples can be obtained and analyzed with relative ease. We have used a combined mining strategy based on an integrated cancer microarray platform, Oncomine, and the biomarker module of the Ingenuity Pathways Analysis (IPA) program to identify po...

  10. Sensitivity of the ATLAS experiment to discover the decay H{yields} {tau}{tau} {yields}ll+4{nu} of the Standard Model Higgs Boson produced in vector boson fusion

    Energy Technology Data Exchange (ETDEWEB)

    Schmitz, Martin

    2011-05-17

    A study of the expected sensitivity of the ATLAS experiment to discover the Standard Model Higgs boson produced via vector boson fusion (VBF) and its decay to H{yields} {tau}{tau}{yields} ll+4{nu} is presented. The study is based on simulated proton-proton collisions at a centre-of-mass energy of 14 TeV. For the first time the discovery potential is evaluated in the presence of additional proton-proton interactions (pile-up) to the process of interest in a complete and consistent way. Special emphasis is placed on the development of background estimation techniques to extract the main background processes Z{yields}{tau}{tau} and t anti t production using data. The t anti t background is estimated using a control sample selected with the VBF analysis cuts and the inverted b-jet veto. The dominant background process Z{yields}{tau}{tau} is estimated using Z{yields}{mu}{mu} events. Replacing the muons of the Z{yields}{mu}{mu} event with simulated {tau}-leptons, Z{yields}{tau}{tau} events are modelled to high precision. For the replacement of the Z boson decay products a dedicated method based on tracks and calorimeter cells is developed. Without pile-up a discovery potential of 3{sigma} to 3.4{sigma} in the mass range 115 GeV

  11. Production of electroweak bosons at colliders

    Indian Academy of Sciences (India)

    Matthias U Mozer

    2012-10-01

    The collider experiments at the Tevatron and LHC are accumulating samples of electroweak bosons of unprecedented size. These huge samples can be used to observe rare processes, such as diboson production which have the potential to show enhancements due to new physics. Alternatively, the great statistical power of the samples allows for detailed studies of electroweak production mechanisms and correspondingly QCD and the proton structure.

  12. Crossover from Bosonic to Fermionic features in Composite Boson Systems

    CERN Document Server

    Thilagam, A

    2013-01-01

    We study the quantum dynamics of conversion of composite bosons into fermionic fragment species with increasing densities of bound fermion pairs using the open quantum system approach. The Hilbert space of $N$-state-function is decomposed into a composite boson subspace and an orthogonal fragment subspace of quasi-free fermions that enlarges as the composite boson constituents deviate from ideal boson commutation relations. The tunneling dynamics of coupled composite boson states in confined systems is examined, and the appearance of exceptional points under experimentally testable conditions (densities, lattice temperatures) is highlighted. The theory is extended to examine the energy transfer between macroscopically coherent systems such as multichromophoric macromolecules (MCMMs) in photosynthetic light harvesting complexes.

  13. Big bang machine searching for the Higgs boson particle

    CERN Document Server

    2015-01-01

    On July 4, 2012, scientists at the giant atom smashing facility at CERN announced the discovery of a subatomic particle that seems like a tantalizingly close match to the elusive Higgs Boson, thought to be responsible for giving all the stuff in the universe its mass. Since it was first proposed nearly fifty years ago, the Higgs has been the holy grail of particle physicists: in finding it they validate the “standard model” that underlies all of modern physics and open the door to new discoveries when CERN’s giant collider switches on at higher power in 2015.

  14. Mott-superfluid transition of q-deformed bosons

    Energy Technology Data Exchange (ETDEWEB)

    Kopeć, T.K., E-mail: kopec@int.pan.wroc.pl

    2015-10-16

    The effect of q-deformation of the bosonic algebra on the Mott-superfluid transition for interacting lattice bosons described by the Bose–Hubbard model is studied using mean-filed theory. It has been shown that the Mott state proliferates and the initial periodicity of the Mott lobes as a function of the chemical potential disappears as the q-deformation increases. The ground state phase diagram as a function of the q-parameter exhibits superfluid order, which intervenes in narrow regions between Mott lobes, demonstrating the new concept of statistically induced quantum phase transition. - Highlights: • We study the effect of q-deformed bosons on superfluid transition. • A mean-field theory is employed. • Bosons can change statistics due to deformation of the commutation rules. • Statistically induced quantum phase transition is found.

  15. ElectroWeak Bosons Couplings

    CERN Document Server

    Ouraou, Ahmimed; The ATLAS collaboration

    2016-01-01

    Latest results on the measurement of gauge boson couplings, from ATLAS and CMS at the LHC, are presented. This review starts with an introduction to boson couplings, then the measurements of Triple and Quartic Couplings are described. And finally, limits on anomalous couplings are summarized.

  16. Guided Discoveries.

    Science.gov (United States)

    Ehrlich, Amos

    1991-01-01

    Presented are four mathematical discoveries made by students on an arithmetical function using the Fibonacci sequence. Discussed is the nature of the role of the teacher in directing the students' discovery activities. (KR)

  17. Volatility Discovery

    DEFF Research Database (Denmark)

    Dias, Gustavo Fruet; Scherrer, Cristina; Papailias, Fotis

    The price discovery literature investigates how homogenous securities traded on different markets incorporate information into prices. We take this literature one step further and investigate how these markets contribute to stochastic volatility (volatility discovery). We formally show...... that the realized measures from homogenous securities share a fractional stochastic trend, which is a combination of the price and volatility discovery measures. Furthermore, we show that volatility discovery is associated with the way that market participants process information arrival (market sensitivity...

  18. A Minimally Symmetric Higgs Boson

    CERN Document Server

    Low, Ian

    2014-01-01

    Models addressing the naturalness of a light Higgs boson typically employ symmetries, either bosonic or fermionic, to stabilize the Higgs mass. We consider a setup with the minimal amount of symmetries: four shift symmetries acting on the four components of the Higgs doublet, subject to the constraints of linearly realized SU(2)xU(1) electroweak symmetry. Up to terms that explicitly violate the shift symmetries, the effective lagrangian can be derived, irrespective of the spontaneously broken group G in the ultraviolet, and is universal in all models where the Higgs arises as a pseudo-Nambu-Goldstone boson (PNGB). Very high energy scatterings of vector bosons could provide smoking gun signals of a minimally symmetric Higgs boson.

  19. Recherche du boson de Higgs dans le canal diphoton au LHC avec le detecteur ATLAS

    CERN Document Server

    AUTHOR|(CDS)2074431; Fayard, Louis

    2008-01-01

    The goal of this thesis is the preparation of the Higgs boson search in its diphoton decay at LHC with the ATLAS detector. The issues that have been studied deal with the Higgs to two photons vertex reconstruction, with the electromagnetic calorimeter and the inner detector, and the diphoton invariant mass resolution.Different simulations of the ATLAS detector and the effects of additional material and of detector misalignements have been studied. Issues concerning the statistical significance calculation have also been discussed and the discovery potential has been evaluated. A part if this thesis is done with CSC data, that use the most recent detector simulation and new reconstruction methods. Every step of the signal and background treatment has been discussed. We finally evaluate that with an integrated luminosity of 10 fb-1 we will be able to see a Higgs to two photons signal with a statistical significance of 3 sigma.

  20. Chips for discovering the Higgs boson and other particles at CERN: Present and future

    CERN Document Server

    Snoeys, W

    2015-01-01

    Integrated circuits and devices revolutionized particle physics experiments, and have been essential in the recent discovery of the Higgs boson by the ATLAS and CMS experiments at the Large Hadron Collider at CERN [1,2]. Particles are accelerated and brought into collision at specific interaction points where detectors, giant cameras of about 40 m long by 20 m in diameter, take pictures of the collision products as they fly away from the collision point. These detectors contain millions of channels, often implemented as reverse biased silicon pin diode arrays covering areas of up to 200 m2 in the center of the experiment, generating a small (~1fC) electric charge upon particle traversals. Integrated circuits provide the readout, and accept collision rates of about 40 MHz with on-line selection of potentially interesting events before data storage. Important limitations are power consumption, radiation tolerance, data rates, and system issues like robustness, redundancy, channel-to-channel uniformity, timing d...

  1. The AEROPATH project targeting Pseudomonas aeruginosa: crystallographic studies for assessment of potential targets in early-stage drug discovery

    Science.gov (United States)

    Moynie, Lucille; Schnell, Robert; McMahon, Stephen A.; Sandalova, Tatyana; Boulkerou, Wassila Abdelli; Schmidberger, Jason W.; Alphey, Magnus; Cukier, Cyprian; Duthie, Fraser; Kopec, Jolanta; Liu, Huanting; Jacewicz, Agata; Hunter, William N.; Naismith, James H.; Schneider, Gunter

    2013-01-01

    Bacterial infections are increasingly difficult to treat owing to the spread of antibiotic resistance. A major concern is Gram-negative bacteria, for which the discovery of new antimicrobial drugs has been particularly scarce. In an effort to accelerate early steps in drug discovery, the EU-funded AEROPATH project aims to identify novel targets in the opportunistic pathogen Pseudomonas aeruginosa by applying a multidisciplinary approach encompassing target validation, structural characterization, assay development and hit identification from small-molecule libraries. Here, the strategies used for target selection are described and progress in protein production and structure analysis is reported. Of the 102 selected targets, 84 could be produced in soluble form and the de novo structures of 39 proteins have been determined. The crystal structures of eight of these targets, ranging from hypothetical unknown proteins to metabolic enzymes from different functional classes (PA1645, PA1648, PA2169, PA3770, PA4098, PA4485, PA4992 and PA5259), are reported here. The structural information is expected to provide a firm basis for the improvement of hit compounds identified from fragment-based and high-throughput screening campaigns. PMID:23295481

  2. Higgs le boson manquant

    CERN Document Server

    Carroll, Sean; Evans, Lyn; Gagnon, Pauline; Bernet, Lison

    2013-01-01

    Ce livre conte l'histoire de la plus fascinante aventure scientifique de notre temps : la quête du "boson de Higgs". La découverte présumée de cette particule élémentaire en juillet 2012 a secoué le monde, tant pour son étrangeté que pour la démesure des moyens déployés. Qu'on en juge : un accélérateur de 27 km de circonférence sous la frontière franco-suisse - le LHC, la plus grande machine jamais construite par l'Homme-, une équipe de 6 000 chercheurs, techniciens, ingénieurs, informaticiens, etc., et un budget de plus de 9 milliards de $ ! L'auteur, cosmologiste et vulgarisateur de renom, nous révèle les enjeux de cette recherche ultime : le boson expliquerait ni plus ni moins pourquoi la matière qui nous entoure a une masse, et lèverait un coin du voile qui entoure la mystérieuse "matière noire". Il détaille surtout sa genèse et les rivalités, les doutes mais aussi les intuitions géniales des acteurs du projet. Cette galerie de personnages hors norme font de la lecture de ce li...

  3. Search for nonminimal neutral Higgs bosons from Z -boson decays

    Energy Technology Data Exchange (ETDEWEB)

    Komamiya, S.; Abrams, G.S.; Adolphsen, C.E.; Averill, D.; Ballam, J.; Barish, B.C.; Barklow, T.; Barnett, B.A.; Bartelt, J.; Bethke, S.; Blockus, D.; Bonvicini, G.; Boyarski, A.; Brabson, B.; Breakstone, A.; Bulos, F.; Burchat, P.R.; Burke, D.L.; Cence, R.J.; Chapman, J.; Chmeissani, M.; Cords, D.; Coupal, D.P.; Dauncey, P.; DeStaebler, H.C.; Dorfan, D.E.; Dorfan, J.M.; Drewer, D.C.; Elia, R.; Feldman, G.J.; Fernandes, D.; Field, R.C.; Ford, W.T.; Fordham, C.; Frey, R.; Fujino, D.; Gan, K.K.; Gatto, C.; Gero, E.; Gidal, G.; Glanzman, T.; Goldhaber, G.; Gomez Cadenas, J.J.; Gratta, G.; Grindhammer, G.; Grosse-Wiesmann, P.; Hanson, G.; Harr, R.; Harral, B.; Harris, F.A.; Hawkes, C.M.; Hayes, K.; Hearty, C.; Heusch, C.A.; Hildreth, M.D.; Himel, T.; Hinshaw, D.A.; Hong, S.J.; Hutchinson, D.; Hylen, J.; Innes, W.R.; Jacobsen, R.G.; Jaros, J.A.; Jung, C.K.; Kadyk, J.A.; Kent, J.; King, M.; Klein, S.R.; Koetke, D.S.; Koska, W.; Kowalski, L.A.; Kozanecki, W.; Kral, J.F.; Kuhlen, M.; Labarga, L

    1990-06-11

    Using the Mark II detector at the SLAC Linear Collider, we search for decays of the {ital Z} boson to a pair of nonminimal Higgs bosons ({ital Z}{r arrow}{ital H}{sub {ital s}}{sup 0}{ital H}{sub {ital p}}{sup 0}), where one of them is relatively light ({approx lt}10 GeV). We find no evidence for these decays and we obtain limits on the {ital ZH}{sub {ital s}}{sup 0}{ital H}{sub {ital p}}{sup 0} coupling as a function of the Higgs-boson masses.

  4. The BEH mechanism and its scalar bosons

    CERN Document Server

    CERN. Geneva

    2014-01-01

    In the beginning of the 1960’s, the long range interactions within our universe were well understood from the laws of classical general relativity, Einstein’s generalisation of Newtonian gravity, and of quantum electrodynamics, the quantum version of Maxwell’s electromagnetic theory. But there was no hints of how to formulate consistent fundamental theories of short range interactions. A solution to this problem was proposed by Robert Brout and me, and independently by Peter Higgs. I shall explain our motivations for constructing this BEH mechanism and discuss its content. I will comment on how the magnificent ATLAS and CMS discovery at CERN of the scalar boson predicted by the mechanism confirms its validity and may have implications on structures at yet unexplored energies.

  5. Coupling chiral bosons to gravity

    CERN Document Server

    Braga, N R F; Braga, N R F; Wotzasek, C

    1995-01-01

    chiral boson actions of Floreanini and Jackiw (FJ), and of McClain,Wu and Yu (MWY) have been recently shown to be different representations of the same chiral boson theory. MWY displays manifest covariance and also a (gauge) symmetry that is hidden in the FJ side, which, on the other hand, displays the physical spectrum in a simple manner. We make use of the covariance of the MWY representation for the chiral boson to couple it to background gravity showing explicitly the equivalence with the previous results for the FJ representation

  6. Vector boson scattering at CLIC

    Energy Technology Data Exchange (ETDEWEB)

    Kilian, Wolfgang; Fleper, Christian [Department Physik, Universitaet Siegen, 57068 Siegen (Germany); Reuter, Juergen [DESY Theory Group, 22603 Hamburg (Germany); Sekulla, Marco [Institut fuer Theoretische Physik, Karlsruher Institut fuer Technologie, 76131 Karlsruhe (Germany)

    2016-07-01

    Linear colliders operating in a range of multiple TeV are able to investigate the details of vector boson scattering and electroweak symmetry breaking. We calculate cross sections with the Monte Carlo generator WHIZARD for vector boson scattering processes at the future linear e{sup +} e{sup -} collider CLIC. By finding suitable cuts, the vector boson scattering signal processes are isolated from the background. Finally, we are able to determine exclusion sensitivities on the non-Standard Model parameters of the relevant dimension eight operators.

  7. Bounding the Higgs boson width through interferometry.

    Science.gov (United States)

    Dixon, Lance J; Li, Ye

    2013-09-13

    We study the change in the diphoton-invariant-mass distribution for Higgs boson decays to two photons, due to interference between the Higgs resonance in gluon fusion and the continuum background amplitude for gg→γγ. Previously, the apparent Higgs mass was found to shift by around 100 MeV in the standard model in the leading-order approximation, which may potentially be experimentally observable. We compute the next-to-leading-order QCD corrections to the apparent mass shift, which reduce it by about 40%. The apparent mass shift may provide a way to measure, or at least bound, the Higgs boson width at the Large Hadron Collider through "interferometry." We investigate how the shift depends on the Higgs width, in a model that maintains constant Higgs boson signal yields. At Higgs widths above 30 MeV, the mass shift is over 200 MeV and increases with the square root of the width. The apparent mass shift could be measured by comparing with the ZZ* channel, where the shift is much smaller. It might be possible to measure the shift more accurately by exploiting its strong dependence on the Higgs transverse momentum.

  8. Higgs boson pizza day | 4 July 2016 | Restaurant 1

    CERN Multimedia

    2016-01-01

    Four years after the historic announcement of the discovery of the Higgs boson at CERN, a collaboration between INFN and CERN has declared 4 July 2016 “Higgs Boson Pizza Day”.    The Novae Restaurant 1 at CERN will offer two special “Higgs Boson Pizzas” (one vegetarian and one ham and cheese), from 11.30 a.m. to 2.15 p.m., for the usual pizza price. The idea was born in Naples (where else?), the hometown of Pierluigi Paolucci, who - while chatting with INFN president Fernando Ferroni - realised the striking resemblance between Higgs boson event displays and the delicious pizzas in front of them. A specially designed pizza was then created by the chef of the historic “Ettore” pizzeria in St. Lucia, in time for the opening of an Art&Science exhibition on 15 September 2015 in Naples. The owner of the restaurant, Ms Iolanda Canale, has been invited by INFN to come to CERN and help Novae in the preparation of 400 pizzas on thi...

  9. Multi-Lepton Signals of the Higgs Boson

    CERN Document Server

    Contreras-Campana, Emmanuel; Gray, Richard; Kilic, Can; Park, Michael; Somalwar, Sunil; Thomas, Scott

    2011-01-01

    The possibility of searching for the Higgs boson in channels with multiple non-resonant leptons is evaluated in light of recent advances in multi-lepton search techniques at the LHC. The total multi-lepton Higgs signal exceeds the four lepton gold-plated resonant mode, but is spread over many channels with same-sign di-lepton, tri-lepton, and four lepton final states. While any individual channel alone is not significant, the exclusive combination across multiple channels is shown to provide a sensitivity competitive with other discovery level searches for the Higgs boson. We estimate that with 5 inverse femtobarn of data, existing non-optimized multi-lepton searches at the LHC could exclude the Higgs boson to 95% CL at a few times the predicted Standard Model cross section in the mass range 120-150 GeV. Refinements focused specifically on the Higgs boson signal are suggested that would further increase sensitivity. We illustrate the possibility of discerning patterns in production and decay modes using corre...

  10. Evolutionary and geological factors controlling endogenic uranium mineralization and the potential for the discovery of new ore districts

    Science.gov (United States)

    Mashkovtsev, G. A.; Miguta, A. K.; Shchetochkin, V. N.

    2015-03-01

    The exhaustion of known surface and near-surface high-grade uranium deposits poses the serious problem of prospecting and exploration of new large endogenic deposits. A comparison of large data sets for endogenic deposits from the world's major uranium districts allowed the authors to develop an evolutionary geological model of large-scale uranium ore genesis, which reflects the succession and nature of preore, ore-forming, and post-ore processes. The study reveals a combination of general (recurrent) factors controlling the formation of ore districts with large-scale uranium mineralization regardless of the genesis and timing of the mineralization. At the same time, these factors depend on the regional setting and can vary considerably among deposits of the same type localized in different tectonic blocks with different characteristics and structural evolution. In connection with this, the exploration of major genetic types of deposits requires the application of specified criteria. Along with the consideration of the evolutionary geological model of ore formation, the study discusses a variety of tectono-magmatic, mineralogical, geochemical, radiogeochemical, and physicochemical factors and indications in three uranium districts (the Streltsovskoe, Elkon, and Central Ukrainian districts), which can form the basis for further uranium prospecting and exploration. Using a combination of favorable prerequisite conditions the study compares the possibilities for the discovery of large endogenic uranium deposits in several regions of Russia.

  11. Search for the Higgs boson in fermionic channels using the ATLAS detector

    CERN Document Server

    Dao, V; The ATLAS collaboration

    2013-01-01

    Since the discovery of a Higgs-like boson by the ATLAS and CMS experiments at the LHC, the emphasis has shifted towards measurements of its properties and the search for the search in the less sensitive channels in order to determine whether the new particle is the Standard Model (SM) Higgs boson. Of particular importance is the direct observation of the coupling of the Higgs boson to tau-leptons, b-quarks and the top-quark. In this presentation a comprehensive review of ATLAS results in the search for the Higgs boson in tau-leptons, b-quark pair decay channel and in the VH and ttH will be given.

  12. Higgs in bosonic channels (CMS

    Directory of Open Access Journals (Sweden)

    Gori Valentina

    2015-01-01

    The Higgs boson mass measurement from the combination of H → ZZ → 4ℓ and H → γγ channels gives a value mH = 125.03+0.26−0.27 (stat. +0.13−0.15 (syst.. An upper limit ΓH < 22 MeV can be put on the Higgs boson width thanks to the new indirect method.

  13. Higgs boson measurements at ATLAS

    CERN Document Server

    Hays, Chris; The ATLAS collaboration

    2016-01-01

    A comprehensive set of Higgs boson measurements has been performed in pp collisions produced by the Large Hadron Collider at centre-of-mass energies of 7 and 8 TeV, and the results combined between the ATLAS and CMS experiments. Recent results from ATLAS at a centre-of-mass energy of 13 TeV are consistent with expectations. With more data available, additional Higgs boson processes are on the cusp of observation, while measured processes promise improved precision.

  14. The Higgs Boson as a Window to Beyond the Standard Model

    Energy Technology Data Exchange (ETDEWEB)

    Vega-Morales, Roberto [Northwestern Univ., Evanston, IL (United States)

    2013-08-01

    The recent discovery of a Higgs boson at the LHC with properties resembling those predicted by the Standard Model (SM) gives strong indication that the final missing piece of the SM is now in place. In particular, the mechanism responsible for Electroweak Symmetry Breaking (EWSB) and generating masses for the Z and W vector bosons appears to have been established. Even with this amazing discovery there are still many outstanding theoretical and phenomenological questions which suggest that there must be physics Beyond the Standard Model (BSM). As we investigate in this thesis, the Higgs boson offers the exciting possibility of acting as a window to this new physics through various avenues which are experimentally testable in the coming years. We investigate a subset of these possibilities and begin by discussing them briefly below before a detailed examination in the following chapters.

  15. Boson Stars with Nontrivial Topology

    CERN Document Server

    Dzhunushaliev, Vladimir; Hoffmann, Christian; Kleihaus, Burkhard; Kunz, Jutta

    2014-01-01

    We construct boson star solutions in the presence of a phantom field, allowing for a nontrivial topology of the solutions. The wormholes residing at the core of the configurations lead to a number of qualitative changes of the boson star solutions. In particular, the typical spiraling dependence of the mass and the particle number on the frequency of the boson stars is lost. Instead, the boson stars with nontrivial topology approach a singular configuration in the limit of vanishing frequency. Depending on the value of the coupling constant, the wormhole geometry changes from a single throat configuration to a double throat configuration, featuring a belly inbetween the two throats. Depending on the mass of the boson field and its self-interaction, the mass and the size of these objects cover many orders of magnitude, making them amenable to various astrophysical observations. A stability analysis reveals, that the unstable mode of the Ellis wormhole is retained in the presence of the bosonic matter. However,...

  16. Recherche du boson de Higgs chargé dans le canal H+ -> tb et étiquetage des jets b avec l'expérience ATLAS auprès du LHC.

    CERN Document Server

    Zaidan, R

    The only particle of the Standard Model that has not yet been discovered is the Higgs boson, which explains the origin of the masses of elementary particles. In the Minimal Supersymmetric extention to the Standard Model (MSSM), the Higgs sector consists of five bosons, two of which are charged. The search for a charged Higgs boson in the gg ¯tbH+(H+ ! t¯b) channel, is the main topic of this analysis. We present an analysis that uses a likelihood function to resolve combinatorics while reconstructing the charged Higgs boson, and the b-tagging to suppress the t¯t+jets background. We also present the difficulties due to the combinatoric background reducing the discovery potential of this channel. The presence of 4 b quarks in the final state that we are looking at, makes the b-tagging an important tool for the analysis. Therefore, a part of this work is dedicated to the study of b-tagging. We present in the context of the preperation for the first data, several studies dedicated to the optimisation and the un...

  17. Molasses or Crowds: Making Sense of the Higgs Boson with Two Popular Analogies

    Science.gov (United States)

    Alsop, S.; Beale, S.

    2013-01-01

    The recent discovery of the Higgs boson at the Large Hadron Collider (LHC) has contributed to a surge of interest in particle physics and science education in general. Given the conceptual difficulty of the phenomenon in question, it is inevitable that teachers and science communicators rely on analogies to explain the Higgs physics and its…

  18. Le cinquantenaire du CERN sous les feux de la rampe: vers le boson de Higgs

    CERN Multimedia

    2004-01-01

    CERN is celebrating today its 50th anniversary. Greatest physic Center in the world, he is setting up actually a new major instrument: the LHC. It should allow the discovery of the Higgs boson, angular stone of the theory of "standard model"

  19. The model-independent analysis for Higgs boson

    Indian Academy of Sciences (India)

    M D NAIMUDDIN; SHIVALI MALHOTRA

    2016-09-01

    The discovery of a 125 GeV particle, announced by the ATLAS and CMS Collaborations on July 04, 2012, is one of the most important events in the recent history of particle physics. This particle could be the last missing particle of the Standard Model of particle physics or it could be the beginning of the long list of particles predicted by the physics beyond the Standard Model. Before we jump to make the final conclusion about this particle, it is imperative to study all the properties of this newly discovered particle. Since the model-dependentanalyses always have this danger of being biased, we can perform a model-independent search for the Higgs boson and also check if the 125 GeV particle is indeed the Standard Model Higgs boson or a particle belonging to the physics beyond the Standard Model.

  20. Measurements of the $W$ boson resonance at LEP2

    CERN Document Server

    D'Hondt, J

    2003-01-01

    The amazing series of experimental discoveries and ingenious theoretical insights of the last century not only profoundly changed the way of our understanding of Nature, but allowed for a relatively simple and unified description of laws governing the processes we observe. The Standard Model of elementary particles arose from this fruitful collaboration between experimental and theoretical researchers. During the late '60s and eraly '70s it was formulated into his final framework, with the prediction of at that time yet undiscovered particles. Among them the W boson, which is one of the most essential particles for electroweak interactions. This thesis presents measurements of the W boson resonance, which is mainly characterized by its pole mass and width. The data accumulated by the DELPHI experiment in e+e- collisions at the LEP machine was used. This experiment provided symmetric collisions of electrons and positrons recreating at a microscopic scale the physics which prevailed about 10^-11 seconds after t...

  1. Discovery of Potential Orthosteric and Allosteric Antagonists of P2Y1R from Chinese Herbs by Molecular Simulation Methods

    Directory of Open Access Journals (Sweden)

    Xu Zhang

    2016-01-01

    Full Text Available P2Y1 receptor (P2Y1R, which belongs to G protein-coupled receptors (GPCRs, is an important target in ADP-induced platelet aggregation. The crystal structure of P2Y1R has been solved recently, which revealed orthosteric and allosteric ligand-binding sites with the details of ligand-protein binding modes. And it suggests that P2Y1R antagonists, which recognize two distinct sites, could potentially provide an efficacious and safe antithrombotic profile. In present paper, 2D similarity search, pharmacophore based screening, and molecular docking were used to explore the potential natural P2Y1R antagonists. 2D similarity search was used to classify orthosteric and allosteric antagonists of P2Y1R. Based on the result, pharmacophore models were constructed and validated by the test set. Optimal models were selected to discover potential P2Y1R antagonists of orthosteric and allosteric sites from Traditional Chinese Medicine (TCM. And the hits were filtered by Lipinski’s rule. Then molecular docking was used to refine the results of pharmacophore based screening and analyze the binding mode of the hits and P2Y1R. Finally, two orthosteric and one allosteric potential compounds were obtained, which might be used in future P2Y1R antagonists design. This work provides a reliable guide for discovering natural P2Y1R antagonists acting on two distinct sites from TCM.

  2. Discovery of Potential Orthosteric and Allosteric Antagonists of P2Y1R from Chinese Herbs by Molecular Simulation Methods

    Science.gov (United States)

    Lu, Fang; Jiang, Lu-di; Qiao, Lian-sheng; Xiang, Yu-hong

    2016-01-01

    P2Y1 receptor (P2Y1R), which belongs to G protein-coupled receptors (GPCRs), is an important target in ADP-induced platelet aggregation. The crystal structure of P2Y1R has been solved recently, which revealed orthosteric and allosteric ligand-binding sites with the details of ligand-protein binding modes. And it suggests that P2Y1R antagonists, which recognize two distinct sites, could potentially provide an efficacious and safe antithrombotic profile. In present paper, 2D similarity search, pharmacophore based screening, and molecular docking were used to explore the potential natural P2Y1R antagonists. 2D similarity search was used to classify orthosteric and allosteric antagonists of P2Y1R. Based on the result, pharmacophore models were constructed and validated by the test set. Optimal models were selected to discover potential P2Y1R antagonists of orthosteric and allosteric sites from Traditional Chinese Medicine (TCM). And the hits were filtered by Lipinski's rule. Then molecular docking was used to refine the results of pharmacophore based screening and analyze the binding mode of the hits and P2Y1R. Finally, two orthosteric and one allosteric potential compounds were obtained, which might be used in future P2Y1R antagonists design. This work provides a reliable guide for discovering natural P2Y1R antagonists acting on two distinct sites from TCM. PMID:27635149

  3. Discovery and biological evaluation of tetrahydrothieno[2,3-c]pyridine derivatives as selective metabotropic glutamate receptor 1 antagonists for the potential treatment of neuropathic pain.

    Science.gov (United States)

    Nam, Mina; Kim, TaeHun; Kwak, Jinsook; Seo, Seon Hee; Ko, Min Kyung; Lim, Eun Jeong; Min, Sun-Joon; Cho, Yong Seo; Keum, Gyochang; Baek, Du-Jong; Lee, Jiyoun; Pae, Ae Nim

    2015-06-05

    Metabotropic glutamate receptor 1 (mGluR1) has been a prime target for drug discovery due to its heavy involvement in various brain disorders. Recent studies suggested that mGluR1 is associated with chronic pain and can serve as a promising target for the treatment of neuropathic pain. In an effort to develop a novel mGluR1 antagonist, we designed and synthesized a library of compounds with tetrahydrothieno[2,3-c]pyridine scaffold. Among these compounds, compound 9b and 10b showed excellent antagonistic activity in vitro and demonstrated pain-suppressing activity in animal models of pain. Both compounds were orally active, and compound 9b exhibited a favorable pharmacokinetic profile in rats. We believe that these compounds can provide a promising lead compound that is suitable for the potential treatment of neuropathic pain.

  4. The Discovery of the Top Quark

    Science.gov (United States)

    Sinervo, P.K.

    1995-12-01

    The top quark and the Higgs boson are the heaviest elementary particles predicted by the standard model. The four lightest quark flavours, the up, down, strange and charm quarks, were well-established by the mid-1970's. The discovery in 1977 of the {Tau} resonances, a new family of massive hadrons, required the introduction of the fifth quark flavour. Experimental and theoretical studies have indicated that this quark also has a heavier partner, the top quark.

  5. Search for the Higgs boson decaying to four leptons in the ATLAS detector at LHC and studies of muon isolation and energy loss

    CERN Document Server

    Lenzi, Bruno; Nicolaidou, Rosy

    2010-01-01

    The central subject of this thesis is the evaluation of the discovery potential of the Higgs boson through its decay into four leptons (electrons and muons) in the ATLAS experiment installed at the Large Hadron Collider (LHC). The LHC was designed to accelerate proton beams at a center of mass energy of 14~TeV and started its physics program with 7~TeV collisions in the beginning of 2010. An inclusive analysis involving all the production modes and an exclusive one aiming at production through vector boson fusion (VBF), studied for the first time in the collaboration, are presented. Both are capable of discovering the Higgs boson after a few years of LHC operation, with integrated luminosities of 30~fb$^{-1}$. The first one covers most part of a Higgs mass window from 130 to 500~GeV. The second one concentrates on masses around 180~GeV and above, exploiting the presence of high energy jets with large separations in pseudo-rapidity to increase the signal over background ratio. An important part of the document...

  6. Theoretical Studies Of Small Boson Clusters

    CERN Document Server

    Chen, Y

    2005-01-01

    This work uses the DVR method to study the vibrational states of small boson clusters. With the adiabatic hyperspherical approximation, the lower and upper bounds of the bound states of the helium trimer are calculated. The first fully converged 3-dimensional basis set variational calculation for this system is carried out using Pekeris coordinates and the Laguerre basis functions. Two bound states are found for the system, as well as a third state which might be an Efimov state. The same method is used to study the bound states and resonance states of the neon trimer using a realistic potential, and proved to be efficient and accurate.

  7. Precision Higgs boson measurement at CLIC

    CERN Document Server

    AUTHOR|(SzGeCERN)718111

    2016-01-01

    The design of the next generation collider in high energy physics will primarily focus on the possibility to achieve high precision of the measurements of interest. The necessary precision limits are set, in the first place, by the measurement of the Higgs boson but also by measurements that are sensitive to signs of New Physics. The Compact Linear Collider (CLIC) is an attractive option for a future multi-TeV linear electron-positron collider, with the potential to cover a rich physics program with high precision. In this lecture the CLIC accelerator, detector and backgrounds will be presented with emphesis on the capabilities of CLIC for precision Higgs physics.

  8. El boson de Higgs

    CERN Document Server

    Gelmini, Graciela B

    2014-01-01

    The last particle that completes the Standard Model of Elementary Particles, the most sophisticated theory of nature in human history, was discovered in 2012. Although the present formulation of the theory comes from the 1960s and 70s, it incorporates all discoveries that thousands of scientists made about elementary particles and their interactions (except for gravity) since the 1700s. Even if briefly, here we review the development of the major concepts included in the theory and explain the relevance of the new particle and the mechanism for which F. Englert and P. Higgs received the Nobel Prize in Physics 2013

  9. Iron K$\\alpha$ line of boson stars

    CERN Document Server

    Cao, Zheng; Zhou, Menglei; Bambi, Cosimo; Herdeiro, Carlos A R; Radu, Eugen

    2016-01-01

    The present paper is a sequel to our previous work [Y. Ni et al., JCAP 1607, 049 (2016)] in which we studied the iron K$\\alpha$ line expected in the reflection spectrum of Kerr black holes with scalar hair. These metrics are solutions of Einstein's gravity minimally coupled to a massive, complex scalar field. They form a continuous bridge between a subset of Kerr black holes and a family of rotating boson stars depending on one extra parameter, the dimensionless scalar hair parameter $q$, ranging from 0 (Kerr black holes) to 1 (boson stars). Here we study the limiting case $q=1$, corresponding to rotating boson stars. For comparison, spherical boson stars are also considered. We simulate observations with XIS/Suzaku. Using the fact that current observations are well fit by the Kerr solution and thus requiring that acceptable alternative compact objects must be compatible with a Kerr fit, we find that some boson star solutions are relatively easy to rule out as potential candidates to explain astrophysical bla...

  10. Higgs production in vector boson fusion in the H{yields} {tau}{tau} {yields} ll + 4{nu} final state with ATLAS. A sensitivity study

    Energy Technology Data Exchange (ETDEWEB)

    Schmitz, Martin

    2011-05-15

    A study of the expected sensitivity of the ATLAS experiment to discover the Standard Model Higgs boson produced via vector boson fusion (VBF) and its decay to H{yields} {tau}{tau} {yields} ll + 4{nu} is presented. The study is based on simulated proton-proton collisions at a centre-of-mass energy of 14 TeV. For the rst time the discovery potential is evaluated in the presence of additional proton-proton interactions (pile-up) to the process of interest in a complete and consistent way. Special emphasis is placed on the development of background estimation techniques to extract the main background processes Z{yields} {tau}{tau} and t anti t production using data. The t anti t background is estimated using a control sample selected with the VBF analysis cuts and the inverted b-jet veto. The dominant background process Z {yields} {tau}{tau} is estimated using Z{yields} {mu}{mu} events. Replacing the muons of the Z{yields} {mu}{mu} event with simulated {tau}-leptons, Z {yields} {tau}{tau} events are modelled to high precision. For the replacement of the Z boson decay products a dedicated method based on tracks and calorimeter cells is developed. Without pile-up a discovery potential of 3{sigma} to 3.4{sigma} in the mass range 115 GeV

  11. Structure-based design, discovery and development of checkpoint kinase inhibitors as potential anti-cancer therapies

    Science.gov (United States)

    Matthews, Thomas P; Jones, Alan M; Collins, Ian

    2014-01-01

    Introduction Checkpoint kinase inhibitors offer the promise of enhancing the effectiveness of widely prescribed cancer chemotherapies and radiotherapy by inhibiting the DNA damage response, as well as the potential for single agent efficacy. Areas covered This article surveys structural insights into the checkpoint kinases CHK1 and CHK2 that have been exploited to enhance the selectivity and potency of small molecule inhibitors. The use of mechanistic cellular assays to guide the optimisation of inhibitors is reviewed. The status of the current clinical candidates and emerging new clinical contexts for CHK1 and CHK2 inhibitors are discussed, including the prospects for single agent efficacy. Expert opinion Protein bound water molecules play key roles in structural features that can be targeted to gain high selectivity for either enzyme. The results of early phase clinical trials of checkpoint inhibitors have been mixed, but significant progress has been made in testing the combination of CHK1 inhibitors with genotoxic chemotherapy. Second generation CHK1 inhibitors are likely to benefit from increased selectivity and oral bioavailability. While the optimum therapeutic context for CHK2 inhibition remains unclear, the emergence of single agent preclinical efficacy for CHK1 inhibitors in specific tumour types exhibiting constitutive replication stress represents exciting progress in exploring the therapeutic potential of these agents. PMID:23594139

  12. Discovery of Potential Inhibitors of Aldosterone Synthase from Chinese Herbs Using Pharmacophore Modeling, Molecular Docking, and Molecular Dynamics Simulation Studies

    Science.gov (United States)

    Lu, Fang; Qiao, Liansheng; Chen, Xi; Li, Gongyu

    2016-01-01

    Aldosterone synthase (CYP11B2) is a key enzyme for the biosynthesis of aldosterone, which plays a significant role for the regulation of blood pressure. Excess aldosterone can cause the dysregulation of the renin-angiotensin-aldosterone system (RAAS) and lead to hypertension. Therefore, research and development of CYP11B2 inhibitor are regarded as a novel approach for the treatment of hypertension. In this study, the pharmacophore models of CYP11B2 inhibitors were generated and the optimal model was used to identify potential CYP11B2 inhibitors from the Traditional Chinese Medicine Database (TCMD, Version 2009). The hits were further refined by molecular docking and the interactions between compounds and CYP11B2 were analyzed. Compounds with high Fitvalue, high docking score, and expected interactions with key residues were selected as potential CYP11B2 inhibitors. Two most promising compounds, ethyl caffeate and labiatenic acid, with high Fitvalue and docking score were reserved for molecular dynamics (MD) study. All of them have stability of ligand binding which suggested that they might perform the inhibitory effect on CYP11B2. This study provided candidates for novel drug-like CYP11B2 inhibitors by molecular simulation methods for the hypertension treatment. PMID:27781210

  13. Discovery of Potential Inhibitors of Aldosterone Synthase from Chinese Herbs Using Pharmacophore Modeling, Molecular Docking, and Molecular Dynamics Simulation Studies

    Directory of Open Access Journals (Sweden)

    Ganggang Luo

    2016-01-01

    Full Text Available Aldosterone synthase (CYP11B2 is a key enzyme for the biosynthesis of aldosterone, which plays a significant role for the regulation of blood pressure. Excess aldosterone can cause the dysregulation of the renin-angiotensin-aldosterone system (RAAS and lead to hypertension. Therefore, research and development of CYP11B2 inhibitor are regarded as a novel approach for the treatment of hypertension. In this study, the pharmacophore models of CYP11B2 inhibitors were generated and the optimal model was used to identify potential CYP11B2 inhibitors from the Traditional Chinese Medicine Database (TCMD, Version 2009. The hits were further refined by molecular docking and the interactions between compounds and CYP11B2 were analyzed. Compounds with high Fitvalue, high docking score, and expected interactions with key residues were selected as potential CYP11B2 inhibitors. Two most promising compounds, ethyl caffeate and labiatenic acid, with high Fitvalue and docking score were reserved for molecular dynamics (MD study. All of them have stability of ligand binding which suggested that they might perform the inhibitory effect on CYP11B2. This study provided candidates for novel drug-like CYP11B2 inhibitors by molecular simulation methods for the hypertension treatment.

  14. Dimensional structural constants from chiral and conformal bosonization of QCD

    CERN Document Server

    Andrianov, A A; Ebert, D; Mann, T F; Mann, Th. Feld

    1997-01-01

    We derive the dimensional non-perturbative part of the QCD effective ac= tion for scalar and pseudoscalar meson fields by means of chiral and conformal bosonization. The related structural coupling constants L_5 and L_8 of th= e chiral lagrangian are estimated using general relations which are valid i= n a variety of chiral bosonization models without explicit reference to model parameters. The asymptotics for large scalar fields in QCD is elaborated,= and model-independent constraints on dimensional coupling constants of the effective meson lagrangian are evaluated. We determine also the interacti= on between scalar quarkonium and the gluon density and obtain the scalar glueball-quarkonium potential.

  15. Boson spectra and correlations for thermal locally equilibrium systems

    CERN Document Server

    Sinyukov, Yu M

    1999-01-01

    The single- and multi- particle inclusive spectra for strongly inhomogeneous thermal boson systems are studied using the method of statistical operator. The thermal Wick's theorem is generalized and the analytical solution of the problem for an boost-invariant expanding boson gas is found. The results demonstrate the effects of inhomogeneity for such a system: the spectra and correlations for particles with wave-lengths larger than the system's homogeneity lengths change essentially as compared with the results based on the local Bose-Einstein thermal distributions. The effects noticeable grow for overpopulated media, where the chemical potential associated with violation of chemical equilibrium is large enough.

  16. Invisible dark gauge boson search in top decays using a kinematic method

    CERN Document Server

    Kim, Doojin; Park, Myeonghun

    2015-01-01

    We discuss the discovery potential of a dark force carrier ($Z'$) of very light mass, $m_{Z'} \\lesssim {\\cal O}(1-10)$ GeV, at hadron colliders via rare top quark decays, especially when it decays invisibly in typical search schemes. We emphasize that the top sector is promising for the discovery of new particles because top quark pairs are copiously produced at the Large Hadron Collider. The signal process is initiated by a rare top decay into a bottom quark and a charged Higgs boson ($H^\\pm$) decaying subsequently into a $W$ and one or multiple $Z'$s. The light $Z'$ can be invisible in collider searches in various scenarios, and it would be hard to distinguish the relevant collider signature from the regular $t\\bar{t}$ process in the Standard Model. We suggest a search strategy using the recently proposed on-shell constrained $M_2$ variables. Our signal process is featured by an $\\textit{asymmetric}$ event topology, while the $t\\bar{t}$ is $\\textit{symmetric}$. The essence behind the strategy is to evoke so...

  17. Discovery of membrane active benzimidazole quinolones-based topoisomerase inhibitors as potential DNA-binding antimicrobial agents.

    Science.gov (United States)

    Zhang, Ling; Addla, Dinesh; Ponmani, Jeyakkumar; Wang, Ao; Xie, Dan; Wang, Ya-Nan; Zhang, Shao-Lin; Geng, Rong-Xia; Cai, Gui-Xin; Li, Shuo; Zhou, Cheng-He

    2016-03-23

    A series of novel benzimidazole quinolones as potential antimicrobial agents were designed and synthesized. Most of the prepared compounds exhibited good or even stronger antimicrobial activities in comparison with reference drugs. The most potent compound 15m was membrane active and did not trigger the development of resistance in bacteria. It not only inhibited the formation of biofilms but also disrupted the established Staphylococcus aureus and Escherichia coli biofilms. It was able to inhibit the relaxation activity of E. coli topoisomerase IV at 10 μM concentration. Moreover, this compound also showed low toxicity against mammalian cells. Molecular modeling and experimental investigation of compound 15m with DNA suggested that this compound could effectively bind with DNA to form a steady 15m-DNA complex which might further block DNA replication to exert the powerful bioactivities.

  18. MOLECULAR MODELING AND DRUG DISCOVERY OF POTENTIAL INHIBITORS FOR ANTICANCER TARGET GENE MELK (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE

    Directory of Open Access Journals (Sweden)

    Sabitha. K

    2011-12-01

    Full Text Available Maternal embryonic leucine zipper kinase (MELK, a member of the AMP serine/threonine kinase family, exhibits multiple features consistent with the potential utility of this gene as an anticancer target. Reports show that MELK functions as a cancer-specific protein kinase, and that down-regulation of MELK results in growth suppression of breast cancer cells. There are many inhibitors which bind to kinases and are in clinical trials too. In our study we have taken a library of different inhibitors and docked those using GLIDE Induced Fit. From docking result we can conclude that Syk inhibitor II, Rho kinase inhibitor IV, p38 MAP Kinase Inhibitor III, HA 1004, Dihydrochloride and IKK -2 inhibitor VI have good binding affinity towards MELK and may have anticancer activity.

  19. Scaling of boson sampling experiments

    Science.gov (United States)

    Drummond, P. D.; Opanchuk, B.; Rosales-Zárate, L.; Reid, M. D.; Forrester, P. J.

    2016-10-01

    Boson sampling is the problem of generating a multiphoton state whose counting probability is the permanent of an n ×n matrix. This is created as the output n -photon coincidence rate of a prototype quantum computing device with n input photons. It is a fundamental challenge to verify boson sampling, and therefore the question of how output count rates scale with matrix size n is crucial. Here we apply results from random matrix theory as well as the characteristic function approach from quantum optics to establish analytical scaling laws for average count rates. We treat boson sampling experiments with arbitrary inputs, outputs, and losses. Using the scaling laws we analyze grouping of channel outputs and the count rates for this case.

  20. Light Front Boson Model Propagation

    Institute of Scientific and Technical Information of China (English)

    Jorge Henrique Sales; Alfredo Takashi Suzuki

    2011-01-01

    stract The scope and aim of this work is to describe the two-body interaction mediated by a particle (either the scalar or the gauge boson) within the light-front formulation. To do this, first of all we point out the importance of propagators and Green functions in Quantum Mechanics. Then we project the covariant quantum propagator onto the light front time to get the propagator for scalar particles in these coordinates. This operator propagates the wave function from x+ = 0 to x+ > O. It corresponds to the definition of the time ordering operation in the light front time x+. We calculate the light-front Green's function for 2 interacting bosons propagating forward in x+. We also show how to write down the light front Green's function from the Feynman propagator and finally make a generalization to N bosons.

  1. Characterization of Si detectors, search for vertex and potentiality of detecting a light charged Higgs boson in the CMS experiment; Caracterisation des detecteurs silicium, recherche de Vertex et etude du potentiel de decouverte d'un boson de Higgs charge leger dans l'experience CMS

    Energy Technology Data Exchange (ETDEWEB)

    Estre, N

    2004-07-01

    The CMS (compact muon solenoid) detector that will be set on the future LHC (large hadron collider) accelerator will enable us to continue our search for the Higgs boson as well as to look for any hint for a new physics beyond the standard model. CMS is composed of an efficient muon detector, an electromagnetic calorimeter and of a tracker with high spatial resolution, this tracker is the topic of this thesis. The tracker will allow an accurate reconstruction of charged-particles trajectories and the reconstruction of the primary interaction vertex. The tracker's technology is based on micro-strip Si detectors, tests performed with the SPS particle beam show that these detectors have an impact reconstruction efficiency greater than 98% and a piling-up rate limited to 6%. The spatial resolution concerning particle trajectories is about 45 {mu}m for an interval of 183 {mu}m between 2 strips. The simulation for the search for a light charged Higgs boson show that an excess of {tau}{nu}{sub {tau}} + bb-bar + qq-bar' events is possible to be observed for any value of tan({beta}) up to M{sub A} = 122 GeV/c{sup 2} during the first year of operation and up to 136 GeV/c{sup 2} afterwards. With the assumption that this event excess is due to the decay of charged Higgs bosons we can state that the assessment of its mass will be possible till m{sub H} = 150 GeV/c{sup 2} with an accuracy of 15 GeV/c{sup 2}. (A.C.)

  2. Discovering the Higgs Bosons of Minimal Supersymmetry with Bottom Quarks

    CERN Document Server

    Kao, Chung; Sayre, Joshua; Wang, Yili

    2009-01-01

    We investigate the prospects for the discovery of a neutral Higgs boson produced with one bottom quark followed by Higgs decay into a pair of bottom quarks at the CERN Large Hadron Collider (LHC) and the Fermilab Tevatron Collider. We work within the framework of the minimal supersymmetric standard model. The dominant physics background is calculated with realistic acceptance cuts and efficiencies including the production of $bb\\bar{b}$, $\\bar{b}b\\bar{b}$, $jb\\bar{b}$ ($j = g, q, \\bar{q}$; $q = u, d, s, c$), $t\\bar{t} \\to b\\bar{b}jj\\ell\

  3. Massive the Higgs boson and the greatest hunt in science

    CERN Document Server

    Sample, Ian

    2013-01-01

    Now fully updated -- this is the dramatic and gripping account of the greatest scientific discovery of our time. In the early 1960s, three groups of physicists, working independently in different countries, stumbled upon an idea that would change physics and fuel the imagination of scientists for decades. That idea was the Higgs boson -- to find it would be to finally understand the origins of mass -- the last building block of life itself. Now, almost 50 years later, that particle has finally been discovered.

  4. Discovery of Potential M2 Channel Inhibitors Based on the Amantadine Scaffold via Virtual Screening and Pharmacophore Modeling

    Directory of Open Access Journals (Sweden)

    Ly Le

    2011-12-01

    Full Text Available The M2 channel protein on the influenza A virus membrane has become the main target of the anti-flu drugs amantadine and rimantadine. The structure of the M2 channel proteins of the H3N2 (PDB code 2RLF and 2009-H1N1 (Genbank accession number GQ385383 viruses may help researchers to solve the drug-resistant problem of these two adamantane-based drugs and develop more powerful new drugs against influenza A virus. In the present study, we searched for new M2 channel inhibitors through a combination of different computational methodologies, including virtual screening with docking and pharmacophore modeling. Virtual screening was performed to calculate the free energies of binding between receptor M2 channel proteins and 200 new designed ligands. After that, pharmacophore analysis was used to identify the important M2 protein-inhibitor interactions and common features of top binding compounds with M2 channel proteins. Finally, the two most potential compounds were determined as novel leads to inhibit M2 channel proteins in both H3N2 and 2009-H1N1 influenza A virus.

  5. Discovery of potential M2 channel inhibitors based on the amantadine scaffold via virtual screening and pharmacophore modeling.

    Science.gov (United States)

    Tran, Linh; Choi, Sy Bing; Al-Najjar, Belal O; Yusuf, Muhammad; Wahab, Habibah A; Le, Ly

    2011-12-08

    The M2 channel protein on the influenza A virus membrane has become the main target of the anti-flu drugs amantadine and rimantadine. The structure of the M2 channel proteins of the H3N2 (PDB code 2RLF) and 2009-H1N1 (Genbank accession number GQ385383) viruses may help researchers to solve the drug-resistant problem of these two adamantane-based drugs and develop more powerful new drugs against influenza A virus. In the present study, we searched for new M2 channel inhibitors through a combination of different computational methodologies, including virtual screening with docking and pharmacophore modeling. Virtual screening was performed to calculate the free energies of binding between receptor M2 channel proteins and 200 new designed ligands. After that, pharmacophore analysis was used to identify the important M2 protein-inhibitor interactions and common features of top binding compounds with M2 channel proteins. Finally, the two most potential compounds were determined as novel leads to inhibit M2 channel proteins in both H3N2 and 2009-H1N1 influenza A virus.

  6. A new approach for potential drug target discovery through in silico metabolic pathway analysis using Trypanosoma cruzi genome information

    Directory of Open Access Journals (Sweden)

    Marcelo Alves-Ferreira

    2009-12-01

    Full Text Available The current drug options for the treatment of chronic Chagas disease have not been sufficient and high hopes have been placed on the use of genomic data from the human parasite Trypanosoma cruzi to identify new drug targets and develop appropriate treatments for both acute and chronic Chagas disease. However, the lack of a complete assembly of the genomic sequence and the presence of many predicted proteins with unknown or unsure functions has hampered our complete view of the parasite's metabolic pathways. Moreover, pinpointing new drug targets has proven to be more complex than anticipated and has revealed large holes in our understanding of metabolic pathways and their integrated regulation, not only for this parasite, but for many other similar pathogens. Using an in silicocomparative study on pathway annotation and searching for analogous and specific enzymes, we have been able to predict a considerable number of additional enzymatic functions in T. cruzi. Here we focus on the energetic pathways, such as glycolysis, the pentose phosphate shunt, the Krebs cycle and lipid metabolism. We point out many enzymes that are analogous to those of the human host, which could be potential new therapeutic targets.

  7. Molecular dynamics simulations of sonic hedgehog-receptor and inhibitor complexes and their applications for potential anticancer agent discovery.

    Directory of Open Access Journals (Sweden)

    Swan Hwang

    Full Text Available The sonic hedgehog (Shh signaling pathway is necessary for a variety of development and differentiation during embryogenesis as well as maintenance and renascence of diverse adult tissues. However, an abnormal activation of the signaling pathway is related to various cancers. In this pathway, the Shh signaling transduction is facilitated by binding of Shh to its receptor protein, Ptch. In this study, we modeled the 3D structure of functionally important key loop peptides of Ptch based on homologous proteins. Using this loop model, the molecular interactions between the structural components present in the pseudo-active site of Shh and key residues of Ptch was investigated in atomic level through molecular dynamics (MD simulations. For the purpose of developing inhibitor candidates of the Shh signaling pathway, the Shh pseudo-active site of this interface region was selected as a target to block the direct binding between Shh and Ptch. Two different structure-based pharmacophore models were generated considering the key loop of Ptch and known inhibitor-induced conformational changes of the Shh through MD simulations. Finally two hit compounds were retrieved through a series of virtual screening combined with molecular docking simulations and we propose two hit compounds as potential inhibitory lead candidates to block the Shh signaling pathway based on their strong interactions to receptor or inhibitor induced conformations of the Shh.

  8. Diphoton channel at the LHC experiments to find a hint for a new heavy gauge boson

    Science.gov (United States)

    Kaneta, Kunio; Kang, Subeom; Lee, Hye-Sung

    2016-09-01

    Recently there has been a huge interest in the diphoton excess around 750 GeV reported by both ATLAS and CMS collaborations, although the newest analysis with more statistics does not seem to support the excess. Nevertheless, the diphoton channel at the LHC experiments are a powerful tool to probe a new physics. One of the most natural explanations of a diphoton excess, if it occurs, could be a new scalar boson with exotic colored particles. In this setup, it would be legitimate to ask what is the role of this new scalar in nature. A heavy neutral gauge boson (Z‧) is one of the traditional targets of the discovery at the collider experiments with numerous motivations. While the Landau-Yang theorem dictates the diphoton excess cannot be this spin-1 gauge boson, there is a strong correlation of a new heavy gauge boson and a new scalar boson which provides a mass to the gauge boson being at the same mass scale. In this paper, we point out a simple fact that a new scalar with a property similar to the recently highlighted 750 GeV would suggest an existence of a TeV scale Z‧ gauge boson that might be within the reach of the LHC Run 2 experiments. We take a scenario of the well-motivated and popular gauged B - L symmetry and require the gauge coupling unification to predict the mass and other properties of the Z‧ and illustrate the discovery of the Z‧ would occur during the LHC experiments.

  9. Cosmic gamma ray detection and discovery potential with the AMS-2 spectrometer; Detection de rayons {gamma} cosmiques et potentiel de decouvertes avec le spectrometre AMS-02

    Energy Technology Data Exchange (ETDEWEB)

    Girard, L

    2004-12-15

    Yet designed to measure charged component of the cosmic rays, the foreseen Alpha Magnetic Spectrometer (AMS-02) could also release {gamma}-ray studies, in the energy range from GeV to TeV, using the tracker system, for {gamma}-rays converted in e{sup +}e{sup -} pair, and the electromagnetic calorimeter. In the first part of the thesis are described the calibrations and the performances of the engineering model of the calorimeter, obtained from the analysis of data taken during a test-beam performed at CERN in July 2002. In the second part of the thesis, the AMS-02 discovery potential for {gamma}-astrophysics is presented. While exposure maps of the {gamma}--sky are computed for one year of data taking with the {gamma}--detectors, the acceptance of the calorimeter is obtained from Monte-Carlo simulations. The AMS-02 potential is then estimated for signals from the Vela pulsar and for some supersymmetric signals from the Galactic Center. (author)

  10. Discovery of potential drugs for human-infecting H7N9 virus containing R294K mutation

    Directory of Open Access Journals (Sweden)

    He JY

    2014-12-01

    Full Text Available Jiao-Yu He,1,* Cheng Li,2,* Guo Wu3 1College of Life Sciences and Key Laboratory for Bio-resources of Ministry of Education, Sichuan University, 2College of Agronomy, Sichuan Agricultural University, 3College of Life Sciences, Sichuan Normal University, Chengdu, People’s Republic of China *These authors contributed equally to this work Background: After the first epidemic wave from February through May 2013, the influenza A (H7N9 virus emerged and has followed a second epidemic wave since June 2013. As of June 27, 2014, the outbreak of H7N9 had caused 450 confirmed cases of human infection, with 165 deaths included. The case-fatality rate of all confirmed cases is about 36%, making the H7N9 virus a significant threat to people’s health. At present, neuraminidase inhibitors are the only licensed antiviral medications available to treat H7N9 infections in humans. Oseltamivir is the most commonly used inhibitor, and it is also a front-line drug for the threatening H7N9. Unfortunately, it has been reported that patients treated with oseltamivir can induce R294K (Arg294Lys substitution in the H7N9 virus, which is a rare mutation and can reduce the antiviral efficacy of inhibitors. Even worse, deaths caused by such mutation after oseltamivir treatment have already been reported, indicating that the need to find substitutive neuraminidase inhibitors for currently available drugs to treat drug-resistant H7N9 is really pressing.Materials and methods: First, the structure of H7N9 containing the R294K substitution was downloaded from the Protein Data Bank, and structural information of approved drugs was downloaded from the ZINC (ZINC Is Not Commercial database. Taking oseltamivir carboxylate as a reference drug, we then filtered these molecules through virtual screening to find out potential inhibitors targeting the mutated H7N9 virus. For further evaluation, we carried out a 14 ns molecular dynamic simulation for each H7N9–drug complex and

  11. Optimization of the ATLAS detector to search for the two-photon decaying Higgs boson at LHC; Optimisation du detecteur ATLAS pour la recherche du boson de Higgs se desintegrant en deux photons au LHC

    Energy Technology Data Exchange (ETDEWEB)

    Tisserand, V. [Paris-11 Univ., 91 - Orsay (France). Lab. de l' Accelerateur Lineaire]|[Universite de Paris Sud, 91 - Orsay (France)

    1997-02-03

    The two photon decay channel is the most clear and promising way to detect a Higgs boson of an intermediate mass between 80 GeV/c{sup 2} and 150 GeV/c{sup 2} at the future large proton collider of CERN (LHC). As the Higgs mass is narrow in this range, the observation of this channel relies on the performance of the electromagnetic calorimeter. A full simulation study has been performed to evaluate the discovery potential of the ATLAS detector. The results of this simulation have been confirmed by beam tests with a prototype. This simulation includes different contributions such as energy resolution sampling term, electronic and pile-up noise, global constant term and angular measurement of the two photon opening angle. The levels of the irreducible background from prompt di-photon production and the reducible background from jets with isolated leading neutrals pions have been estimated, taking into account the rejection capability of the detector. After the computation of the two photon invariant mass resolution, and the evaluation of signal and background rates, the discovery potential of the Higgs boson with the ATLAS detector was calculated. The Higgs can be discovered at five sigma confidence level after less than a year of data taking at LHC with the nominal luminosity of 10{sup 34} cm{sup -2}.s{sup -1} if the Higgs mass is between 100 GeV/c{sup 2} and 150 GeV/c{sup 2}. The Higgs mass window between 80 GeV/c{sup 2} and 150 GeV/c{sup 2} will be covered with an integrated luminosity of 3.10{sup 5} pb{sup -1}. In the case of the Minimal Supersymmetric Model (MSSM) the plane (m{sub A{sup 0}}, tan({beta})) will be fully explored if m{sub A{sup 0}} > 175 GeV/c{sup 2}. (author)

  12. Development, evaluation and application of 3D QSAR Pharmacophore model in the discovery of potential human renin inhibitors

    Directory of Open Access Journals (Sweden)

    John Shalini

    2011-12-01

    potential inhibitory leads were identified to be used in designing novel and future renin inhibitors as antihypertensive drugs.

  13. W.K.H. Panofsky Prize: The Long Journey to the Higgs Boson: CMS

    Science.gov (United States)

    Virdee, Tejinder

    2017-01-01

    There has been a rich harvest of physics from the experiments at the Large Hadron Collider (LHC). In July 2012, the ground-breaking discovery of the Higgs boson was made by the ATLAS and CMS experiments. This boson is a long-sought particle expected from the mechanism for spontaneous symmetry breaking in the electro-weak sector that provides an explanation of how elementary particles acquire mass. The discovery required experiments of unprecedented capability and complexity. This talk, complementing that of Peter Jenni, will trace the background to the search for the Higgs boson at the LHC, the conception, the construction and the operation of the CMS experiment, and its subsequent discovery of the boson. The SM is considered to be a low energy manifestation of a more complete theory - physics beyond the SM is therefore widely anticipated. Selected CMS results will be presented from the search for physics beyond the SM from the 13 TeV Run-2 at the LHC.

  14. Study of associated production of W-Higgs boson with the ATLAS detector

    CERN Document Server

    AUTHOR|(INSPIRE)INSPIRE-00235896

    On the 4$^{th}$ of July 2012 both the ATLAS and CMS experiments announced the observation of a new particle in the search for the Standard Model Higgs boson. This observation contributes to the assignment of the Nobel Prize in Physics 2013 to P. Higgs and F. Englert ``for the theoretical discovery of a mechanism that contributes to our understanding of the origin of mass of subatomic particles, and which recently was confirmed through the discovery of the predicted fundamental particle, by the ATLAS and CMS experiments at CERN's Large Hadron Collider'' (http://www.nobelprize.org/nobel\\_prizes/physics/). After the discovery, the effort was focused on the study of the properties of the observed particle with data acquired in 2011 and 2012 years. The main goal of this thesis is to present a study of one of the Standard Model (SM) Higgs boson production mechanisms allowed at the Large Hadron Collider (LHC). The presented analysis is focused on the Higgs boson produced in association with a vector boson W and a $H...

  15. Proteomics-Based Characterization of the Humoral Immune Response in Sporotrichosis: Toward Discovery of Potential Diagnostic and Vaccine Antigens

    Science.gov (United States)

    Rodrigues, Anderson Messias; Fernandes, Geisa Ferreira; Araujo, Leticia Mendes; Della Terra, Paula Portella; dos Santos, Priscila Oliveira; Pereira, Sandro Antonio; Schubach, Tânia Maria Pacheco; Burger, Eva; Lopes-Bezerra, Leila Maria; de Camargo, Zoilo Pires

    2015-01-01

    understanding of the coevolution of Sporothrix and its warm-blooded hosts. We propose that 3-carboxymuconate cyclase has potential for the serological diagnosis of sporotrichosis and as target for the development of an effective multi-species vaccine against sporotrichosis in animals and humans. PMID:26305691

  16. Proteomics-Based Characterization of the Humoral Immune Response in Sporotrichosis: Toward Discovery of Potential Diagnostic and Vaccine Antigens.

    Directory of Open Access Journals (Sweden)

    Anderson Messias Rodrigues

    understanding of the coevolution of Sporothrix and its warm-blooded hosts. We propose that 3-carboxymuconate cyclase has potential for the serological diagnosis of sporotrichosis and as target for the development of an effective multi-species vaccine against sporotrichosis in animals and humans.

  17. Amniotic fluid cathelicidin in PPROM pregnancies: from proteomic discovery to assessing its potential in inflammatory complications diagnosis.

    Directory of Open Access Journals (Sweden)

    Vojtech Tambor

    Full Text Available BACKGROUND: Preterm prelabor rupture of membranes (PPROM complicated by microbial invasion of the amniotic cavity (MIAC leading to histological chorioamnionitis (HCA significantly impacts perinatal morbidity. Unfortunately, no well-established tool for identifying PPROM patients threatened by these disorders is available. METHODOLOGY/PRINCIPAL FINDINGS: We performed an unbiased exploratory analysis of amniotic fluid proteome changes due to MIAC and HCA. From among the top five proteins that showed the most profound and significant change, we sought to confirm results concerning cathelicidin (P49913, CAMP_HUMAN, since an ELISA kit was readily available for this protein. In our exploratory proteomic study, cathelicidin showed a ∼6-fold higher concentration in PPROM patients with confirmed MIAC and HCA. We verified significantly higher levels of cathelicidin in exploratory samples (women without both MIAC and HCA: median 1.4 ng/ml; women with both conditions confirmed: median 3.6 ng/ml; p = 0.0003. A prospective replication cohort was used for independent validation and for assessment of cathelicidin potential to stratify women with MIAC leading to HCA from women in whom at least one of these conditions was ruled out. We confirmed the association of higher amniotic fluid cathelicidin levels with MIAC leading to HCA (the presence of both MIAC and HCA: median 3.1 ng/ml; other women: median 1.4 ng/ml; p<0.0001. A cathelicidin concentration of 4.0 ng/ml was found to be the best cut-off point for identifying PPROM women with both MIAC and HCA. When tested on the validation cohort, a sensitivity of 48%, a specificity of 90%, a likelihood ratio of 5.0, and an area under receiver-operating characteristic curve of 71% were achieved for identification of women with MIAC leading to HCA. CONCLUSIONS: Our multi-stage study suggests cathelicidin as a candidate marker that should be considered for a panel of amniotic fluid proteins permitting identification

  18. Universality and quantized response in bosonic mesoscopic tunneling

    Science.gov (United States)

    Yin, Shaoyu; Béri, Benjamin

    2016-06-01

    We show that tunneling involving bosonic wires and/or boson integer quantum Hall (bIQH) edges is characterized by features that are far more universal than those in their fermionic counterpart. Considering a pair of minimal geometries, we examine the tunneling conductance as a function of energy (e.g., chemical potential bias) at high and low energy limits, finding a low energy enhancement and a universal high versus zero energy relation that hold for all wire/bIQH edge combinations. Beyond this universality present in all the different topological (bIQH-edge) and nontopological (wire) setups, we also discover a number of features distinguishing the topological bIQH edges, which include a current imbalance to chemical potential bias ratio that is quantized despite the lack of conductance quantization in the bIQH edges themselves. The predicted phenomena require only initial states to be thermal and thus are well suited for tests with ultracold bosons forming wires and bIQH states. For the latter, we highlight a potential realization based on single component bosons in the recently observed Harper-Hofstadter band structure.

  19. Search for the Higgs Boson in the Channel H→ZZ(*)→4l with the ATLAS Detector

    CERN Document Server

    Rebuzzi, D; The ATLAS collaboration

    2009-01-01

    The decay channel H→ZZ(∗)→4ℓ provides a clean signature for the Higgs boson in the mass range between ∼120 GeV/c2 and 2MZ, above which the gold-plated channel with two real Z bosons in the final state opens up. The signal cross section is several orders of magnitude smaller than those for the backgrounds, therefore a thorough understanding of the multi-lepton processes is needed to obtain a high background rejection. Crucial for this channel is a very good understanding of the trigger and detector response for lepton identification and reconstruction. In order to compute an exclusion limit, a good knowledge of the back- grounds as well as of the signal selection efficiency after all analysis cut is needed. The observability of the signal on top of the reducible t¯t, Zb¯b and W Z and of the irreducible Z Z backgrounds is discussed in detail, with particular emphasis on the lepton reconstruction. We evaluate the ATLAS discovery potential for the H → 4ℓ channel, including the most realistic and...

  20. A Higgcision study on the 750 GeV Di-photon Resonance and 125 GeV SM Higgs boson with the Higgs-Singlet Mixing

    CERN Document Server

    Cheung, Kingman; Lee, Jae Sik; Park, Jubin; Tseng, Po-Yan

    2015-01-01

    We interpret the potential observation of the 750 GeV di-photon resonance at the LHC in models, in which an $SU(2)$ isospin-singlet scalar boson mixes with the Standard Model (SM) Higgs boson through an angle $\\alpha$. Allowing the singlet scalar boson to have renormalizable couplings to vector-like leptons and quarks, we can explain the large production cross section $\\sigma(H_2) \\times B(H_2 \\to \\gamma\\gamma)$ as well as the apparent large total width of the boson without conflicts from the results obtained by previous global fits to the SM Higgs boson data.

  1. Resummation predictions for new electroweak gauge boson production

    Energy Technology Data Exchange (ETDEWEB)

    Lamprea, David R.; Klasen, Michael [Institut fuer Theoretische Physik, Universitaet Muenster, Wilhelm-Klemm-Strasse 9, D-48149 Muenster (Germany); Jezo, Tomas; Lyonnet, Florian; Schienbein, Ingo [Universite Joseph Fourier/CNRS-IN2P3/INPG, 53 Avenue des Martyrs, F-38026 Grenoble (France)

    2013-07-01

    After the discovery of a particle compatible with the SM Higgs boson, it is now necessary to shift the attention towards theories Beyond the Standard Model (BSM) that aim to solve some of the several issues that the the SM presents. Many promising candidate for BSM physics are based on the enlargement of the SM gauge groups either from a Grand Unification Theory (GUT) point of view (superstring-inspired or not) or with models that address particular issues (e.g. left-right models). One of the properties of these models is the appearance of new gauge bosons (Z' and W'). Resummation is an improvement over fixed-order perturbative QCD in kinematical regions where these predictions become unreliable. It restores the convergence properties in these regions and overall improves the precision of the computations. In this work we present resummation predictions for new gauge bosons Z' and W' for several GUT and non-GUT models in the context of general phenomenological frameworks that allow the analysis of a wide range of theoretical possibilities.

  2. Higgs in Bosonic channel (CMS)

    CERN Document Server

    Gori, Valentina

    2015-01-01

    All the investigated properties result to be fully consistent with the SM predictions: the signal strength and the signal strength modifiers are consistent with unity in all the bosonic channels considered; the hypothesis of a scalar particle is strongly favored, ag...

  3. Gravitational Stability of Boson Stars

    CERN Document Server

    Kusmartsev, Fjodor V; Schunck, Franz E

    1991-01-01

    We investigate the stability of general-relativistic boson stars by classifying singularities of differential mappings and compare it with the results of perturbation theory. Depending on the particle number, the star has the following regimes of behavior: stable, metastable, pulsation, and collapse.

  4. Per-residue energy decomposition pharmacophore model to enhance virtual screening in drug discovery: a study for identification of reverse transcriptase inhibitors as potential anti-HIV agents.

    Science.gov (United States)

    Cele, Favourite N; Ramesh, Muthusamy; Soliman, Mahmoud Es

    2016-01-01

    A novel virtual screening approach is implemented herein, which is a further improvement of our previously published "target-bound pharmacophore modeling approach". The generated pharmacophore library is based only on highly contributing amino acid residues, instead of arbitrary pharmacophores, which are most commonly used in the conventional approaches in literature. Highly contributing amino acid residues were distinguished based on free binding energy contributions obtained from calculation from molecular dynamic (MD) simulations. To the best of our knowledge; this is the first attempt in the literature using such an approach; previous approaches have relied on the docking score to generate energy-based pharmacophore models. However, docking scores are reportedly unreliable. Thus, we present a model for a per-residue energy decomposition, constructed from MD simulation ensembles generating a more trustworthy pharmacophore model, which can be applied in drug discovery workflow. This work is aimed at introducing a more rational approach to the field of drug design, rather than comparing the validity of this approach against those previously reported. We recommend additional computational and experimental work to further validate this approach. This approach was used to screen for potential reverse transcriptase inhibitors using the pharmacophoric features of compound GSK952. The complex was subjected to docking, thereafter, MD simulation confirmed the stability of the system. Experimentally determined inhibitors with known HIV-reverse transcriptase inhibitory activity were used to validate the protocol. Two potential hits (ZINC46849657 and ZINC54359621) showed a significant potential with regard to free binding energy. Reported results obtained from this work confirm that this new approach is favorable in the future of the drug design industry.

  5. Beyond Discovery

    DEFF Research Database (Denmark)

    Korsgaard, Steffen; Sassmannshausen, Sean Patrick

    2015-01-01

    as their central concepts and conceptualization of the entrepreneurial function. On this basis we discuss three central themes that cut across the four alternatives: process, uncertainty, and agency. These themes provide new foci for entrepreneurship research and can help to generate new research questions......In this chapter we explore four alternatives to the dominant discovery view of entrepreneurship; the development view, the construction view, the evolutionary view, and the Neo-Austrian view. We outline the main critique points of the discovery presented in these four alternatives, as well...

  6. Phenomenological analysis of the interacting boson model

    Science.gov (United States)

    Hatch, R. L.; Levit, S.

    1982-01-01

    The classical Hamiltonian of the interacting boson model is defined and expressed in terms of the conventional quadrupole variables. This is used in the analyses of the dynamics in the various limits of the model. The purpose is to determine the range and the features of the collective phenomena which the interacting boson model is capable of describing. In the commonly used version of the interacting boson model with one type of the s and d bosons and quartic interactions, this capability has certain limitations and the model should be used with care. A more sophisticated version of the interacting boson model with neutron and proton bosons is not discussed. NUCLEAR STRUCTURE Interacting bosons, classical IBM Hamiltonian in quadrupole variables, phenomenological content of the IBM and its limitations.

  7. Search for Higgs bosons in the final state ZZ(*)-->llqq with the ATLAS detector at the LHC

    CERN Document Server

    AUTHOR|(INSPIRE)INSPIRE-00009427; Fassouliotis, Dimitrios; Kourkoumelis, Christine; Polychronakos, Venetios

    2016-04-25

    This dissertation presents the search for Higgs-like bosons, in the decay mode H->ZZ(*)->llqq, using data collected with the ATLAS detector, at the CERN Large Hadron Collider (LHC). Despite the fact that this channel is mostly sensitive in the Higgs boson mass range above 200 GeV, before the discovery of the Standard Model Higgs boson the search was extended over the mass interval 120-180 GeV. Reasonable sensitivity is observed above 140 GeV. The search uses 4.7 ifb of proton–proton collision data, at a centre-of-mass energy of 7 TeV. After the discovery of the Higgs boson, the search focused towards the detection of additional, heavy Higgs bosons, in the mass range 200-1000 GeV. Proton–proton collision data, at a centre-of-mass energy of 8 TeV, are used, corresponding to an integrated luminosity of 20.3 ifb. Since no significant excess of events is observed over the Standard Model prediction, upper limits are set, at 95% confidence level (CL), on the production cross-section of a heavy Higgs boson times ...

  8. Optogenetics enlightens neuroscience drug discovery.

    Science.gov (United States)

    Song, Chenchen; Knöpfel, Thomas

    2016-02-01

    Optogenetics - the use of light and genetics to manipulate and monitor the activities of defined cell populations - has already had a transformative impact on basic neuroscience research. Now, the conceptual and methodological advances associated with optogenetic approaches are providing fresh momentum to neuroscience drug discovery, particularly in areas that are stalled on the concept of 'fixing the brain chemistry'. Optogenetics is beginning to translate and transit into drug discovery in several key domains, including target discovery, high-throughput screening and novel therapeutic approaches to disease states. Here, we discuss the exciting potential of optogenetic technologies to transform neuroscience drug discovery.

  9. Relativistic Coulomb scattering of spinless bosons

    CERN Document Server

    Garcia, M G

    2015-01-01

    The relativistic scattering of spin-0 bosons by spherically symmetric Coulomb fields is analyzed in detail with an arbitrary mixing of vector and scalar couplings. It is shown that the partial wave series reduces the scattering amplitude to the closed Rutherford formula exactly when the vector and scalar potentials have the same magnitude, and as an approximation for weak fields. The behavior of the scattering amplitude near the conditions that furnish its closed form is also discussed. Strong suppressions of the scattering amplitude when the vector and scalar potentials have the same magnitude are observed either for particles or antiparticles with low incident momentum. We point out that such strong suppressions might be relevant in the analysis of the scattering of fermions near the conditions for the spin and pseudospin symmetries. From the complex poles of the partial scattering amplitude the exact closed form of bound-state solutions for both particles and antiparticles with different scenarios for the ...

  10. Étude du potentiel de découverte du boson de Higgs produit par fusion de bosons vectoriels qq a qq H par le détecteur ATLAS au LHC

    CERN Document Server

    Mazini, Rachid

    At the LHC, the vector boson fusion production mode will have a major im- pact on the Standard Model Higgs searches. The characteristic signature of two addition al jets in the forward regions of the detector and the low hadronic activity in the central part allows for a powerful rejection of background processes. This process is also the unique way for detecting H -t 7+7- decay mode. The work presented in this thesis shows the prospect for a Higgs boson, with H -t 7+ 7- and 100 < MH < 150 GeV jc 2 , discovery in ATLAS using vector boson fusion. In addi- tion, the production of the dominant background pro cess pp -t Z + 2 jets is studied using several theoretical approaches. Finally, The ATLAS Forward Calorimeter will have a major role in detecting and reconstructing the forward jets associated with the Higgs boson. A comparison with a GEANT4-based Monte Carl...

  11. The future (and past) of quantum theory after the Higgs boson: a quantum-informational viewpoint.

    Science.gov (United States)

    Plotnitsky, Arkady

    2016-05-28

    Taking as its point of departure the discovery of the Higgs boson, this article considers quantum theory, including quantum field theory, which predicted the Higgs boson, through the combined perspective of quantum information theory and the idea of technology, while also adopting anon-realistinterpretation, in 'the spirit of Copenhagen', of quantum theory and quantum phenomena themselves. The article argues that the 'events' in question in fundamental physics, such as the discovery of the Higgs boson (a particularly complex and dramatic, but not essentially different, case), are made possible by the joint workings of three technologies: experimental technology, mathematical technology and, more recently, digital computer technology. The article will consider the role of and the relationships among these technologies, focusing on experimental and mathematical technologies, in quantum mechanics (QM), quantum field theory (QFT) and finite-dimensional quantum theory, with which quantum information theory has been primarily concerned thus far. It will do so, in part, by reassessing the history of quantum theory, beginning with Heisenberg's discovery of QM, in quantum-informational and technological terms. This history, the article argues, is defined by the discoveries of increasingly complex configurations of observed phenomena and the emergence of the increasingly complex mathematical formalism accounting for these phenomena, culminating in the standard model of elementary-particle physics, defining the current state of QFT.

  12. On Bosonic Magnetic Flux Operator and Bosonic Faraday Operator Formula

    Institute of Scientific and Technical Information of China (English)

    FAN Hong-Yi; WANG Tong-Tong; WANG Ji-Suo

    2007-01-01

    In the literature about mesoscopic Josephson devices the magnetic flux is considered as an operator, the fundamental commutative relation between the magnetic flux operator and the Cooper-pair charge operator is usually preengaged. In this paper we show that such a relation can be deduced from the basic Bose operators' commutative relation through the entangled state representation. The Faraday formula in bosonic form is then equivalent to the second Josephson equation. The current operator equation for LC mesoscopic circuit is also derived.

  13. Search for the Standard Model Higgs boson produced in association with top quarks with the ATLAS detector

    Science.gov (United States)

    Qin, Yang

    2016-11-01

    After the discovery of a new particle consistent with the Higgs boson in 2012, the direct observation and measurement of the coupling of this particle to top quarks has become increasingly important. In this talk, a review of the latest ATLAS results on the search for the Higgs boson produced in association with top quarks, tt¯H, is presented. In particular, three analyses aiming at different tt¯H final states are reviewed. These include a search with the Higgs boson decaying to bb¯, a search in multileptonic final states and a search with H → γγ. The results from these analyses are combined, giving a tt¯H signal strength of 1:8±0:8 and excluding a tt¯H signal 3.2 larger than the SM expectation at 95% confidence level for a SM Higgs boson with a mass of 125.36 GeV.

  14. Three-loop corrections to the Higgs boson mass and implications for supersymmetry at the LHC.

    Science.gov (United States)

    Feng, Jonathan L; Kant, Philipp; Profumo, Stefano; Sanford, David

    2013-09-27

    In supersymmetric models with minimal particle content and without left-right squark mixing, the conventional wisdom is that the 125.6 GeV Higgs boson mass implies top squark masses of O(10)  TeV, far beyond the reach of colliders. This conclusion is subject to significant theoretical uncertainties, however, and we provide evidence that it may be far too pessimistic. We evaluate the Higgs boson mass, including the dominant three-loop terms at O(αtαs2), in currently viable models. For multi-TeV top squarks, the three-loop corrections can increase the Higgs boson mass by as much as 3 GeV and lower the required top-squark masses to 3-4 TeV, greatly improving prospects for supersymmetry discovery at the upcoming run of the LHC and its high-luminosity upgrade.

  15. 3-Loop Corrections to the Higgs Boson Mass and Implications for Supersymmetry at the LHC

    CERN Document Server

    Feng, Jonathan L; Profumo, Stefano; Sanford, David

    2013-01-01

    In supersymmetric models with minimal particle content and without left-right squark mixing, the conventional wisdom is that the 125.6 GeV Higgs boson mass implies top squark masses of ~10 TeV, far beyond the reach of colliders. This conclusion is subject to significant theoretical uncertainties, however, and we provide evidence that it may be far too pessimistic. We evaluate the Higgs boson mass, including the dominant three-loop terms at O(\\alpha_t \\alpha_s^2), in currently viable models. For multi-TeV stops, the three-loop corrections can increase the Higgs boson mass by as much as 3 GeV and lower the required stop mass to 3 to 4 TeV, greatly improving prospects for supersymmetry discovery at the upcoming run of the LHC and its high-luminosity upgrade.

  16. The Interplay Between Collider Searches For Supersymmetric Higgs Bosons and Direct Dark Matter Experiments

    Energy Technology Data Exchange (ETDEWEB)

    Carena, Marcela; Hooper, Dan; /Fermilab; Vallinotto, Alberto; /Fermilab /Chicago U. /Paris, Inst. Astrophys.

    2006-11-01

    In this article, we explore the interplay between searches for supersymmetric particles and Higgs bosons at hadron colliders (the Tevatron and the LHC) and direct dark matter searches (such as CDMS, ZEPLIN, XENON, EDELWEISS, CRESST, WARP and others). We focus on collider searches for heavy MSSM Higgs bosons (A, H, H{sup {+-}}) and how the prospects for these searches are impacted by direct dark matter limits and vice versa. We find that the prospects of these two experimental programs are highly interrelated. A positive detection of A, H or H{sup {+-}} at the Tevatron would dramatically enhance the prospects for a near future direct discovery of neutralino dark matter. Similarly, a positive direct detection of neutralino dark matter would enhance the prospects of discovering heavy MSSM Higgs bosons at the Tevatron or the LHC. Combining the information obtained from both types of experimental searches will enable us to learn more about the nature of supersymmetry.

  17. Mixed QCD-EW corrections for Higgs boson production at $e^+e^-$ colliders

    CERN Document Server

    Gong, Yinqiang; Xu, Xiaofeng; Yang, Li Lin

    2016-01-01

    Since the discovery of the Higgs boson at the Large Hadron Collider, a future electron-position collider has been proposed for precisely studying its properties. We investigate the production of the Higgs boson at such an $e^+e^-$ collider and calculate for the first time the mixed QCD-electroweak corrections to the total cross sections. We find that the $\\mathcal{O}(\\alpha\\alpha_s)$ corrections amount to a $1.2\\%$ increase of the cross section for a center-of-mass energy around 250 GeV. This is larger than the expected experimental accuracy and has to be included for extracting the properties of the Higgs boson from the measurements of the cross sections in the future.

  18. Vector-Boson Fusion and Vector-Boson Scattering

    CERN Document Server

    Rauch, Michael

    2016-01-01

    Vector-boson fusion and vector-boson scattering are an important class of processes for the Large Hadron Collider at CERN. It is characterized by two high-energetic jets in the forward regions of the detector and reduced jet activity in the central region. The higher center-of-mass energy during the current and subsequent runs strongly boosts the sensitivity in these processes and allows to test the predictions of the Standard Model to a high precision. In this review, we first present the main phenomenological features of vector-boson fusion and scattering processes. Then we discuss the effects of higher-order corrections, which are available at NLO QCD for all processes and up to N3LO QCD and NLO electro-weak for VBF-H production. An additional refinement is the addition of parton-shower effects, where recently a lot of progress has been made. The appearance of triple and quartic gauge vertices in the production processes enables us to probe anomalous gauge couplings. We introduce and compare the different ...

  19. A proposal for a scalable universal bosonic simulator using individually trapped ions

    CERN Document Server

    Lau, Hoi-Kwan

    2012-01-01

    We describe a possible architecture to implement a universal bosonic simulator (UBS) using trapped ions. Single ions are confined in individual traps, and their motional states represent the bosonic modes. Single-mode linear operators, nonlinear phase-shifts, and linear beam splitters can be realized by precisely controlling the trapping potentials. All the processes in a bosonic simulation, except the initialization and the readout, can be conducted beyond the Lamb-Dicke regime. Aspects of our proposal can also be applied to split adiabatically a pair of ions in a single trap.

  20. Introduction to bosonic string theory

    Energy Technology Data Exchange (ETDEWEB)

    Nunez, Carmen [Instituto de Astronomia y Fisica del Espacio, Buenos Aires (Argentina)], e-mail: carmen@iafe.uba.ar

    2009-07-01

    This is an introductory set of five lectures on bosonic string theory. The first one deals with the classical theory of bosonic strings. The second and third lectures cover quantization. Three basic quantization methods are sketched: the old covariant formalism, the light-cone gauge quantization, where the spectrum is derived and the Polyakov path integral formalism and in particular the partition function at one loop. Finally, the last lecture covers interactions, low energy effective action, the general idea of compactification and in particular toroidal compactification. The notes are based on books by Green, Schwarz and Witten, Polchinski, Lust and Theissen and Kaku and review papers by D'Hocker and Phong and O. Alvarez. (author)

  1. A general approach to bosonization

    Indian Academy of Sciences (India)

    Girish S Setulur; V Meera

    2007-10-01

    We summarize recent developments in the field of higher dimensional bosonization made by Setlur and collaborators and propose a general formula for the field operator in terms of currents and densities in one dimension using a new ingredient known as a `singular complex number'. Using this formalism, we compute the Green function of the homogeneous electron gas in one spatial dimension with short-range interaction leading to the Luttinger liquid and also with long-range interactions that lead to a Wigner crystal whose momentum distribution computed recently exhibits essential singularities. We generalize the formalism to finite temperature by combining with the author's hydrodynamic approach. The one-particle Green function of this system with essential singularities cannot be easily computed using the traditional approach to bosonization which involves the introduction of momentum cutoffs, hence the more general approach of the present formalism is proposed as a suitable alternative.

  2. Bosonic colored group field theory

    Energy Technology Data Exchange (ETDEWEB)

    Ben Geloun, Joseph [Universite Paris XI, Laboratoire de Physique Theorique, Orsay Cedex (France); University of Abomey-Calavi, Cotonou (BJ). International Chair in Mathematical Physics and Applications (ICMPA-UNESCO Chair); Universite Cheikh Anta Diop, Departement de Mathematiques et Informatique, Faculte des Sciences et Techniques, Dakar (Senegal); Magnen, Jacques [Ecole Polytechnique, Centre de Physique Theorique, Palaiseau Cedex (France); Rivasseau, Vincent [Universite Paris XI, Laboratoire de Physique Theorique, Orsay Cedex (France)

    2010-12-15

    Bosonic colored group field theory is considered. Focusing first on dimension four, namely the colored Ooguri group field model, the main properties of Feynman graphs are studied. This leads to a theorem on optimal perturbative bounds of Feynman amplitudes in the ''ultraspin'' (large spin) limit. The results are generalized in any dimension. Finally, integrating out two colors we write a new representation, which could be useful for the constructive analysis of this type of models. (orig.)

  3. One or more Higgs bosons?

    CERN Document Server

    Barbieri, Riccardo; Kannike, Kristjan; Sala, Filippo; Tesi, Andrea

    2013-01-01

    Now that one has been found, the search for signs of more scalars is a primary task of current and future experiments. In the motivated hypothesis that the extra Higgs bosons of the next-to-minimal supersymmetric Standard Model (NMSSM) be the lightest new particles around, we outline a possible overall strategy to search for signs of the CP-even states. This work complements Ref. arXiv:1304.3670.

  4. Distinguishing a SM-like MSSM Higgs boson from SM Higgs boson at muon collider

    Indian Academy of Sciences (India)

    Jai Kumar Singhal; Sardar Singh; Ashok K Nagawat

    2007-06-01

    We explore the possibility of distinguishing the SM-like MSSM Higgs boson from the SM Higgs boson via Higgs boson pair production at future muon collider. We study the behavior of the production cross-section in SM and MSSM with Higgs boson mass for various MSSM parameters tan and A. We observe that at fixed CM energy, in the SM, the total cross-section increases with the increase in Higgs boson mass whereas this trend is reversed for the MSSM. The changes that occur for the MSSM in comparison to the SM predictions are quantified in terms of the relative percentage deviation in cross-section. The observed deviations in cross-section for different choices of Higgs boson masses suggest that the measurements of the cross-section could possibly distinguish the SM-like MSSM Higgs boson from the SM Higgs boson.

  5. RAS - Screens & Assays - Drug Discovery

    Science.gov (United States)

    The RAS Drug Discovery group aims to develop assays that will reveal aspects of RAS biology upon which cancer cells depend. Successful assay formats are made available for high-throughput screening programs to yield potentially effective drug compounds.

  6. Interview to prof. Peter Higgs about the latest results on the searches for the Higgs boson at the LHC

    CERN Multimedia

    CERN Video Productions

    2012-01-01

    Peter Higgs answers questions about his feelings following the announcement of the discovery of a new particle by ATLAS and CMS that looks like the Higgs boson, at a seminar at CERN on July 4, 2012. He also explains his role in the proposal of a Higgs mechanism.

  7. Vector-boson production in p + Pb collisions measured with ATLAS at the LHC

    Science.gov (United States)

    Grabowska-Bold, I.

    2016-12-01

    Electroweak-boson production processes (W, Z and photon) provide access to the earliest moments of heavy-ion collisions. Furthermore, because they do not undergo strong interactions, they are sensitive to the initial-state geometry of the collision and potentially the details of the nuclear parton distribution functions. ATLAS results on vector-boson yields have demonstrated binary collision scaling in Pb+Pb collisions. In p + Pb collisions, the measurement of vector bosons provides possible constraints on the nuclear parton distribution functions and insights into the details of the initial collision geometry. We report on the latest results of vector-boson production in p + Pb collisions at √{sNN} = 5.02 TeV. Production yields of Z and W bosons and lepton charge asymmetry of W bosons are presented as a function of pseudo-rapidity and centrality. The vector-boson yields are compared to calculations incorporating different parton distribution functions, as well as different centrality calculations.

  8. Searching heavier Higgs boson via di-Higgs production at LHC Run-2

    Directory of Open Access Journals (Sweden)

    Lan-Chun Lü

    2016-04-01

    Full Text Available The discovery of a light Higgs particle h0(125 GeV opens up new prospect for searching heavier Higgs boson(s at the LHC Run-2, which will unambiguously point to new physics beyond the standard model (SM. We study the detection of a heavier neutral Higgs boson H0 via di-Higgs production channel at the LHC (14 TeV, H0→h0h0→WW⁎γγ. This directly probes the Hhh cubic Higgs interaction, which exists in most extensions of the SM Higgs sector. For the decay products of final states WW⁎, we include both pure leptonic mode WW⁎→ℓν¯ℓ¯ν and semi-leptonic mode WW⁎→qq¯′ℓν. We analyze signals and backgrounds by performing fast detector simulation for the full process pp→H→hh→WW⁎γγ→ℓν¯ℓ¯νγγ and pp→H→hh→WW⁎γγ→ℓνqq¯′γγ, over the mass range MH=250–600 GeV. For generic two-Higgs-doublet models (2HDM, we present the discovery reach of the heavier Higgs boson at the LHC Run-2, and compare it with the current Higgs global fit of the 2HDM parameter space.

  9. Searching heavier Higgs boson via di-Higgs production at LHC Run-2

    Science.gov (United States)

    Lü, Lan-Chun; Du, Chun; Fang, Yaquan; He, Hong-Jian; Zhang, Huijun

    2016-04-01

    The discovery of a light Higgs particle h0 (125 GeV) opens up new prospect for searching heavier Higgs boson(s) at the LHC Run-2, which will unambiguously point to new physics beyond the standard model (SM). We study the detection of a heavier neutral Higgs boson H0 via di-Higgs production channel at the LHC (14 TeV), H0 →h0h0 → WW* γγ. This directly probes the Hhh cubic Higgs interaction, which exists in most extensions of the SM Higgs sector. For the decay products of final states WW*, we include both pure leptonic mode WW* → ℓ ν bar ℓ bar ν and semi-leptonic mode WW* → qqbar‧ ℓν. We analyze signals and backgrounds by performing fast detector simulation for the full process pp → H → hh → WW* γγ → ℓ ν bar ℓ bar νγγ and pp → H → hh → WW* γγ → ℓνqqbar‧ γγ, over the mass range MH = 250- 600 GeV. For generic two-Higgs-doublet models (2HDM), we present the discovery reach of the heavier Higgs boson at the LHC Run-2, and compare it with the current Higgs global fit of the 2HDM parameter space.

  10. Charged Higgs Boson Search at the LHC

    CERN Document Server

    Roy, D P

    2005-01-01

    This review starts with a brief introduction to the charged Higgs boson $(H^\\pm)$ in the Minimal Supersymmetric Standard Model (MSSM). It then discusses the prospects of a relatively light $H^\\pm$ boson search via top quark decay and finally a heavy $H^\\pm$ boson search at LHC. The viable channels for $H^\\pm$ search are discussed, with particular emphasis on the $H^\\pm -> tau+nu$ decay channel.

  11. A Search for Dark Higgs Bosons

    Energy Technology Data Exchange (ETDEWEB)

    Lees, J.P.

    2012-06-08

    Recent astrophysical and terrestrial experiments have motivated the proposal of a dark sector with GeV-scale gauge boson force carriers and new Higgs bosons. We present a search for a dark Higgs boson using 516 fb{sup -1} of data collected with the BABAR detector. We do not observe a significant signal and we set 90% confidence level upper limits on the product of the Standard Model-dark sector mixing angle and the dark sector coupling constant.

  12. Grand Unification, Higgs Bosons, and Baryogenesis

    Science.gov (United States)

    Sher, Marc

    2004-03-01

    My task in these lectures is to discuss "Grand Unification and Higgs Bosons". Given that each of these subjects has had books written about them, this is a daunting task. My goal will be to introduce the basics of each topic, and provide references for those who wish to explore the topics further. I'll begin with a general motivation for grand unification, followed with an elementary review of SU(N) group algebra. The seminal SU(5) model will be discussed, followed by the supersymmetric version. On the second day, we'll look at other grand unified theories, and then look at the various methods of supersymmetry breaking in the context of grand unification. The third day, we'll turn to the Higgs mechanism, the effective potential, and mass bounds in the Standard Model and the MSSM. Finally, we'll look at baryogenesis, first in grand unified theories and then in the electroweak model.

  13. New Results on Charged Compact Boson Stars

    CERN Document Server

    Kumar, Sanjeev; Kulshreshtha, Daya Shankar

    2016-01-01

    In this work we present some new results which we have obtained in a study of the phase diagram of charged compact boson stars in the theory involving massive complex scalar fields coupled to the U(1) gauge field and gravity in a conical potential in the presence of a cosmological constant $\\Lambda$ which we treat as a free parameter taking positive and negative values and thereby allowing us to study the theory in the de Sitter and Anti de Sitter spaces respectively. In our studies, we obtain four bifurcation points (possibility of more bifurcation points being not ruled out) in the de Sitter region. We present a detailed discussion of the various regions in our phase diagram with respect to four bifurcation points. Our theory is seen to have rich physics in a particular domain for positive values of $\\Lambda$ which is consistent with the accelerated expansion of the universe.

  14. Modified Scattering for the Boson Star Equation

    Science.gov (United States)

    Pusateri, Fabio

    2014-12-01

    We consider the question of scattering for the boson star equation in three space dimensions. This is a semi-relativistic Klein-Gordon equation with a cubic nonlinearity of Hartree type. We combine weighted estimates, obtained by exploiting a special null structure present in the equation, and a refined asymptotic analysis performed in Fourier space, to obtain global solutions evolving from small and localized Cauchy data. We describe the behavior of such solutions at infinity by identifying a suitable nonlinear asymptotic correction to scattering. As a byproduct of the weighted energy estimates alone, we also obtain global existence and (linear) scattering for solutions of semi-relativistic Hartree equations with potentials decaying faster than Coulomb.

  15. Measurements of the Higgs Boson in the $H\\rightarrow\\tau\\tau$ Decay Channel

    CERN Document Server

    Howard, Jacob

    The generation of vector boson mass via the Higgs mechanism in the Standard Model has been confirmed by the 2012 discovery of a candidate Higgs boson in the $H\\rightarrow{WW}$, $H\\rightarrow{ZZ}$, and $H\\rightarrow\\gamma\\gamma$ decay channels. In contrast, the Yukawa couplings hypothesized to provide the mass of fermions in the Standard Model have yet to be observed. The $H\\rightarrow\\tau\\tau$ decay channel currently provides the best opportunity for observing these couplings. This thesis describes two separate but related searches for Higgs boson decays in the $H\\rightarrow\\tau\\tau$ decay channel using proton-proton collisions recorded by the ATLAS detector. The first analysis is a general search for all Higgs boson production mechanisms leading to a $H\\rightarrow\\tau\\tau$ decay using 4.5 fb$^{-1}$ of 7 TeV and 20.3 fb$^{-1}$ of 8 TeV proton-proton collision data. A deviation from the background-only hypothesis is observed with a significance of $4.5\\sigma$ for a hypothetical Higgs boson mass of ${m_{H} ...

  16. Evidence for the direct decay of the 125 GeV Higgs boson to fermions

    CERN Document Server

    Chatrchyan, Serguei; Sirunyan, Albert M; Tumasyan, Armen; Adam, Wolfgang; Bergauer, Thomas; Dragicevic, Marko; Erö, Janos; Fabjan, Christian; Friedl, Markus; Fruehwirth, Rudolf; Ghete, Vasile Mihai; Hartl, Christian; Hörmann, Natascha; Hrubec, Josef; Jeitler, Manfred; Kiesenhofer, Wolfgang; Knünz, Valentin; Krammer, Manfred; Krätschmer, Ilse; Liko, Dietrich; Mikulec, Ivan; Rabady, Dinyar; Rahbaran, Babak; Rohringer, Herbert; Schöfbeck, Robert; Strauss, Josef; Taurok, Anton; Treberer-Treberspurg, Wolfgang; Waltenberger, Wolfgang; Wulz, Claudia-Elisabeth; Mossolov, Vladimir; Shumeiko, Nikolai; Suarez Gonzalez, Juan; Alderweireldt, Sara; Bansal, Monika; Bansal, Sunil; Cornelis, Tom; De Wolf, Eddi A; Janssen, Xavier; Knutsson, Albert; Luyckx, Sten; Ochesanu, Silvia; Roland, Benoit; Rougny, Romain; Van Haevermaet, Hans; Van Mechelen, Pierre; Van Remortel, Nick; Van Spilbeeck, Alex; Blekman, Freya; Blyweert, Stijn; D'Hondt, Jorgen; Heracleous, Natalie; Kalogeropoulos, Alexis; Keaveney, James; Kim, Tae Jeong; Lowette, Steven; Maes, Michael; Olbrechts, Annik; Python, Quentin; Strom, Derek; Tavernier, Stefaan; Van Doninck, Walter; Van Mulders, Petra; Van Onsem, Gerrit Patrick; Villella, Ilaria; Caillol, Cécile; Clerbaux, Barbara; De Lentdecker, Gilles; Favart, Laurent; Gay, Arnaud; Léonard, Alexandre; Marage, Pierre Edouard; Mohammadi, Abdollah; Perniè, Luca; Reis, Thomas; Seva, Tomislav; Thomas, Laurent; Vander Velde, Catherine; Vanlaer, Pascal; Wang, Jian; Adler, Volker; Beernaert, Kelly; Benucci, Leonardo; Cimmino, Anna; Costantini, Silvia; Crucy, Shannon; Dildick, Sven; Garcia, Guillaume; Klein, Benjamin; Lellouch, Jérémie; Mccartin, Joseph; Ocampo Rios, Alberto Andres; Ryckbosch, Dirk; Salva Diblen, Sinem; Sigamani, Michael; Strobbe, Nadja; Thyssen, Filip; Tytgat, Michael; Walsh, Sinead; Yazgan, Efe; Zaganidis, Nicolas; Basegmez, Suzan; Beluffi, Camille; Bruno, Giacomo; Castello, Roberto; Caudron, Adrien; Ceard, Ludivine; Da Silveira, Gustavo Gil; Delaere, Christophe; Du Pree, Tristan; Favart, Denis; Forthomme, Laurent; Giammanco, Andrea; Hollar, Jonathan; Jez, Pavel; Komm, Matthias; Lemaitre, Vincent; Liao, Junhui; Militaru, Otilia; Nuttens, Claude; Pagano, Davide; Pin, Arnaud; Piotrzkowski, Krzysztof; Popov, Andrey; Quertenmont, Loic; Selvaggi, Michele; Vidal Marono, Miguel; Vizan Garcia, Jesus Manuel; Beliy, Nikita; Caebergs, Thierry; Daubie, Evelyne; Hammad, Gregory Habib; Alves, Gilvan; Correa Martins Junior, Marcos; Dos Reis Martins, Thiago; Pol, Maria Elena; Henrique Gomes E Souza, Moacyr; Aldá Júnior, Walter Luiz; Carvalho, Wagner; Chinellato, Jose; Custódio, Analu; Da Costa, Eliza Melo; De Jesus Damiao, Dilson; De Oliveira Martins, Carley; Fonseca De Souza, Sandro; Malbouisson, Helena; Malek, Magdalena; Matos Figueiredo, Diego; Mundim, Luiz; Nogima, Helio; Prado Da Silva, Wanda Lucia; Santaolalla, Javier; Santoro, Alberto; Sznajder, Andre; Tonelli Manganote, Edmilson José; Vilela Pereira, Antonio; Bernardes, Cesar Augusto; De Almeida Dias, Flavia; Tomei, Thiago; De Moraes Gregores, Eduardo; Mercadante, Pedro G; Novaes, Sergio F; Padula, Sandra; Genchev, Vladimir; Iaydjiev, Plamen; Marinov, Andrey; Piperov, Stefan; Rodozov, Mircho; Sultanov, Georgi; Vutova, Mariana; Dimitrov, Anton; Glushkov, Ivan; Hadjiiska, Roumyana; Kozhuharov, Venelin; Litov, Leander; Pavlov, Borislav; Petkov, Peicho; Bian, Jian-Guo; Chen, Guo-Ming; Chen, He-Sheng; Chen, Mingshui; Du, Ran; Jiang, Chun-Hua; Liang, Dong; Liang, Song; Meng, Xiangwei; Plestina, Roko; Tao, Junquan; Wang, Xianyou; Wang, Zheng; Asawatangtrakuldee, Chayanit; Ban, Yong; Guo, Yifei; Li, Qiang; Li, Wenbo; Liu, Shuai; Mao, Yajun; Qian, Si-Jin; Wang, Dayong; Zhang, Linlin; Zou, Wei; Avila, Carlos; Chaparro Sierra, Luisa Fernanda; Florez, Carlos; Gomez, Juan Pablo; Gomez Moreno, Bernardo; Sanabria, Juan Carlos; Godinovic, Nikola; Lelas, Damir; Polic, Dunja; Puljak, Ivica; Antunovic, Zeljko; Kovac, Marko; Brigljevic, Vuko; Kadija, Kreso; Luetic, Jelena; Mekterovic, Darko; Morovic, Srecko; Sudic, Lucija; Attikis, Alexandros; Mavromanolakis, Georgios; Mousa, Jehad; Nicolaou, Charalambos; Ptochos, Fotios; Razis, Panos A; Bodlak, Martin; Finger, Miroslav; Finger Jr, Michael; Assran, Yasser; Elgammal, Sherif; Ellithi Kamel, Ali; Mahmoud, Mohammed; Mahrous, Ayman; Radi, Amr; Kadastik, Mario; Müntel, Mait; Murumaa, Marion; Raidal, Martti; Tiko, Andres; Eerola, Paula; Fedi, Giacomo; Voutilainen, Mikko; Härkönen, Jaakko; Karimäki, Veikko; Kinnunen, Ritva; Kortelainen, Matti J; Lampén, Tapio; Lassila-Perini, Kati; Lehti, Sami; Lindén, Tomas; Luukka, Panja-Riina; Mäenpää, Teppo; Peltola, Timo; Tuominen, Eija; Tuominiemi, Jorma; Tuovinen, Esa; Wendland, Lauri; Tuuva, Tuure; Besancon, Marc; Couderc, Fabrice; Dejardin, Marc; Denegri, Daniel; Fabbro, Bernard; Faure, Jean-Louis; Favaro, Carlotta; Ferri, Federico; Ganjour, Serguei; Givernaud, Alain; Gras, Philippe; Hamel de Monchenault, Gautier; Jarry, Patrick; Locci, Elizabeth; Malcles, Julie; Nayak, Aruna; Rander, John; Rosowsky, André; Titov, Maksym; Baffioni, Stephanie; Beaudette, Florian; Busson, Philippe; Charlot, Claude; Daci, Nadir; Dahms, Torsten; Dalchenko, Mykhailo; Dobrzynski, Ludwik; Filipovic, Nicolas; Florent, Alice; Granier de Cassagnac, Raphael; Mastrolorenzo, Luca; Miné, Philippe; Mironov, Camelia; Naranjo, Ivo Nicolas; Nguyen, Matthew; Ochando, Christophe; Paganini, Pascal; Sabes, David; Salerno, Roberto; Sauvan, Jean-baptiste; Sirois, Yves; Veelken, Christian; Yilmaz, Yetkin; Zabi, Alexandre; Agram, Jean-Laurent; Andrea, Jeremy; Bloch, Daniel; Brom, Jean-Marie; Chabert, Eric Christian; Collard, Caroline; Conte, Eric; Drouhin, Frédéric; Fontaine, Jean-Charles; Gelé, Denis; Goerlach, Ulrich; Goetzmann, Christophe; Juillot, Pierre; Le Bihan, Anne-Catherine; Van Hove, Pierre; Gadrat, Sébastien; Beauceron, Stephanie; Beaupere, Nicolas; Boudoul, Gaelle; Brochet, Sébastien; Carrillo Montoya, Camilo Andres; Chasserat, Julien; Chierici, Roberto; Contardo, Didier; Depasse, Pierre; El Mamouni, Houmani; Fan, Jiawei; Fay, Jean; Gascon, Susan; Gouzevitch, Maxime; Ille, Bernard; Kurca, Tibor; Lethuillier, Morgan; Mirabito, Laurent; Perries, Stephane; Ruiz Alvarez, José David; Sgandurra, Louis; Sordini, Viola; Vander Donckt, Muriel; Verdier, Patrice; Viret, Sébastien; Xiao, Hong; Tsamalaidze, Zviad; Autermann, Christian; Beranek, Sarah; Bontenackels, Michael; Calpas, Betty; Edelhoff, Matthias; Feld, Lutz; Hindrichs, Otto; Klein, Katja; Ostapchuk, Andrey; Perieanu, Adrian; Raupach, Frank; Sammet, Jan; Schael, Stefan; Sprenger, Daniel; Weber, Hendrik; Wittmer, Bruno; Zhukov, Valery; Ata, Metin; Caudron, Julien; Dietz-Laursonn, Erik; Duchardt, Deborah; Erdmann, Martin; Fischer, Robert; Güth, Andreas; Hebbeker, Thomas; Heidemann, Carsten; Hoepfner, Kerstin; Klingebiel, Dennis; Knutzen, Simon; Kreuzer, Peter; Merschmeyer, Markus; Meyer, Arnd; Olschewski, Mark; Padeken, Klaas; Papacz, Paul; Reithler, Hans; Schmitz, Stefan Antonius; Sonnenschein, Lars; Teyssier, Daniel; Thüer, Sebastian; Weber, Martin; Cherepanov, Vladimir; Erdogan, Yusuf; Flügge, Günter; Geenen, Heiko; Geisler, Matthias; Haj Ahmad, Wael; Hoehle, Felix; Kargoll, Bastian; Kress, Thomas; Kuessel, Yvonne; Lingemann, Joschka; Nowack, Andreas; Nugent, Ian Michael; Perchalla, Lars; Pooth, Oliver; Stahl, Achim; Asin, Ivan; Bartosik, Nazar; Behr, Joerg; Behrenhoff, Wolf; Behrens, Ulf; Bell, Alan James; Bergholz, Matthias; Bethani, Agni; Borras, Kerstin; Burgmeier, Armin; Cakir, Altan; Calligaris, Luigi; Campbell, Alan; Choudhury, Somnath; Costanza, Francesco; Diez Pardos, Carmen; Dooling, Samantha; Dorland, Tyler; Eckerlin, Guenter; Eckstein, Doris; Eichhorn, Thomas; Flucke, Gero; Geiser, Achim; Grebenyuk, Anastasia; Gunnellini, Paolo; Habib, Shiraz; Hauk, Johannes; Hellwig, Gregor; Hempel, Maria; Horton, Dean; Jung, Hannes; Kasemann, Matthias; Katsas, Panagiotis; Kieseler, Jan; Kleinwort, Claus; Krämer, Mira; Krücker, Dirk; Lange, Wolfgang; Leonard, Jessica; Lipka, Katerina; Lohmann, Wolfgang; Lutz, Benjamin; Mankel, Rainer; Marfin, Ihar; Melzer-Pellmann, Isabell-Alissandra; Meyer, Andreas Bernhard; Mnich, Joachim; Mussgiller, Andreas; Naumann-Emme, Sebastian; Novgorodova, Olga; Nowak, Friederike; Ntomari, Eleni; Perrey, Hanno; Petrukhin, Alexey; Pitzl, Daniel; Placakyte, Ringaile; Raspereza, Alexei; Ribeiro Cipriano, Pedro M; Riedl, Caroline; Ron, Elias; Sahin, Mehmet Özgür; Salfeld-Nebgen, Jakob; Saxena, Pooja; Schmidt, Ringo; Schoerner-Sadenius, Thomas; Schröder, Matthias; Stein, Matthias; Vargas Trevino, Andrea Del Rocio; Walsh, Roberval; Wissing, Christoph; Aldaya Martin, Maria; Blobel, Volker; Centis Vignali, Matteo; Enderle, Holger; Erfle, Joachim; Garutti, Erika; Goebel, Kristin; Görner, Martin; Gosselink, Martijn; Haller, Johannes; Höing, Rebekka Sophie; Kirschenmann, Henning; Klanner, Robert; Kogler, Roman; Lange, Jörn; Lapsien, Tobias; Lenz, Teresa; Marchesini, Ivan; Ott, Jochen; Peiffer, Thomas; Pietsch, Niklas; Rathjens, Denis; Sander, Christian; Schettler, Hannes; Schleper, Peter; Schlieckau, Eike; Schmidt, Alexander; Seidel, Markus; Sibille, Jennifer; Sola, Valentina; Stadie, Hartmut; Steinbrück, Georg; Troendle, Daniel; Usai, Emanuele; Vanelderen, Lukas; Barth, Christian; Baus, Colin; Berger, Joram; Böser, Christian; Butz, Erik; Chwalek, Thorsten; De Boer, Wim; Descroix, Alexis; Dierlamm, Alexander; Feindt, Michael; Guthoff, Moritz; Hartmann, Frank; Hauth, Thomas; Held, Hauke; Hoffmann, Karl-Heinz; Husemann, Ulrich; Katkov, Igor; Kornmayer, Andreas; Kuznetsova, Ekaterina; Lobelle Pardo, Patricia; Martschei, Daniel; Mozer, Matthias Ulrich; Müller, Thomas; Niegel, Martin; Nürnberg, Andreas; Oberst, Oliver; Quast, Gunter; Rabbertz, Klaus; Ratnikov, Fedor; Röcker, Steffen; Schilling, Frank-Peter; Schott, Gregory; Simonis, Hans-Jürgen; Stober, Fred-Markus Helmut; Ulrich, Ralf; Wagner-Kuhr, Jeannine; Wayand, Stefan; Weiler, Thomas; Wolf, Roger; Zeise, Manuel; Anagnostou, Georgios; Daskalakis, Georgios; Geralis, Theodoros; Giakoumopoulou, Viktoria Athina; Kesisoglou, Stilianos; Kyriakis, Aristotelis; Loukas, Demetrios; Markou, Athanasios; Markou, Christos; Psallidas, Andreas; Topsis-Giotis, Iasonas; Gouskos, Loukas; Panagiotou, Apostolos; Saoulidou, Niki; Stiliaris, Efstathios; Aslanoglou, Xenofon; Evangelou, Ioannis; Flouris, Giannis; Foudas, Costas; Jones, John; Kokkas, Panagiotis; Manthos, Nikolaos; Papadopoulos, Ioannis; Paradas, Evangelos; Bencze, Gyorgy; Hajdu, Csaba; Hidas, Pàl; Horvath, Dezso; Sikler, Ferenc; Veszpremi, Viktor; Vesztergombi, Gyorgy; Zsigmond, Anna Julia; Beni, Noemi; Czellar, Sandor; Molnar, Jozsef; Palinkas, Jozsef; Szillasi, Zoltan; Karancsi, János; Raics, Peter; Trocsanyi, Zoltan Laszlo; Ujvari, Balazs; Swain, Sanjay Kumar; Beri, Suman Bala; Bhatnagar, Vipin; Dhingra, Nitish; Gupta, Ruchi; Kaur, Manjit; Mittal, Monika; Nishu, Nishu; Sharma, Archana; Singh, Jasbir; Kumar, Ashok; Kumar, Arun; Ahuja, Sudha; Bhardwaj, Ashutosh; Choudhary, Brajesh C; Kumar, Ajay; Malhotra, Shivali; Naimuddin, Md; Ranjan, Kirti; Sharma, Varun; Shivpuri, Ram Krishen; Banerjee, Sunanda; Bhattacharya, Satyaki; Chatterjee, Kalyanmoy; Dutta, Suchandra; Gomber, Bhawna; Jain, Sandhya; Jain, Shilpi; Khurana, Raman; Modak, Atanu; Mukherjee, Swagata; Roy, Debarati; Sarkar, Subir; Sharan, Manoj; Singh, Anil; Abdulsalam, Abdulla; Dutta, Dipanwita; Kailas, Swaminathan; Kumar, Vineet; Mohanty, Ajit Kumar; Pant, Lalit Mohan; Shukla, Prashant; Topkar, Anita; Aziz, Tariq; Chatterjee, Rajdeep Mohan; Ganguly, Sanmay; Ghosh, Saranya; Guchait, Monoranjan; Gurtu, Atul; Kole, Gouranga; Kumar, Sanjeev; Maity, Manas; Majumder, Gobinda; Mazumdar, Kajari; Mohanty, Gagan Bihari; Parida, Bibhuti; Sudhakar, Katta; Wickramage, Nadeesha; Banerjee, Sudeshna; Dewanjee, Ram Krishna; Dugad, Shashikant; Arfaei, Hessamaddin; Bakhshiansohi, Hamed; Behnamian, Hadi; Etesami, Seyed Mohsen; Fahim, Ali; Jafari, Abideh; Khakzad, Mohsen; Mohammadi Najafabadi, Mojtaba; Naseri, Mohsen; Paktinat Mehdiabadi, Saeid; Safarzadeh, Batool; Zeinali, Maryam; Grunewald, Martin; Abbrescia, Marcello; Barbone, Lucia; Calabria, Cesare; Chhibra, Simranjit Singh; Colaleo, Anna; Creanza, Donato; De Filippis, Nicola; De Palma, Mauro; Fiore, Luigi; Iaselli, Giuseppe; Maggi, Giorgio; Maggi, Marcello; My, Salvatore; Nuzzo, Salvatore; Pacifico, Nicola; Pompili, Alexis; Pugliese, Gabriella; Radogna, Raffaella; Selvaggi, Giovanna; Silvestris, Lucia; Singh, Gurpreet; Venditti, Rosamaria; Verwilligen, Piet; Zito, Giuseppe; Abbiendi, Giovanni; Benvenuti, Alberto; Bonacorsi, Daniele; Braibant-Giacomelli, Sylvie; Brigliadori, Luca; Campanini, Renato; Capiluppi, Paolo; Castro, Andrea; Cavallo, Francesca Romana; Codispoti, Giuseppe; Cuffiani, Marco; Dallavalle, Gaetano-Marco; Fabbri, Fabrizio; Fanfani, Alessandra; Fasanella, Daniele; Giacomelli, Paolo; Grandi, Claudio; Guiducci, Luigi; Marcellini, Stefano; Masetti, Gianni; Meneghelli, Marco; Montanari, Alessandro; Navarria, Francesco; Odorici, Fabrizio; Perrotta, Andrea; Primavera, Federica; Rossi, Antonio; Rovelli, Tiziano; Siroli, Gian Piero; Tosi, Nicolò; Travaglini, Riccardo; Albergo, Sebastiano; Cappello, Gigi; Chiorboli, Massimiliano; Costa, Salvatore; Giordano, Ferdinando; Potenza, Renato; Tricomi, Alessia; Tuve, Cristina; Barbagli, Giuseppe; Ciulli, Vitaliano; Civinini, Carlo; D'Alessandro, Raffaello; Focardi, Ettore; Gallo, Elisabetta; Gonzi, Sandro; Gori, Valentina; Lenzi, Piergiulio; Meschini, Marco; Paoletti, Simone; Sguazzoni, Giacomo; Tropiano, Antonio; Benussi, Luigi; Bianco, Stefano; Fabbri, Franco; Piccolo, Davide; Fabbricatore, Pasquale; Ferro, Fabrizio; Lo Vetere, Maurizio; Musenich, Riccardo; Robutti, Enrico; Tosi, Silvano; Dinardo, Mauro Emanuele; Fiorendi, Sara; Gennai, Simone; Gerosa, Raffaele; Ghezzi, Alessio; Govoni, Pietro; Lucchini, Marco Toliman; Malvezzi, Sandra; Manzoni, Riccardo Andrea; Martelli, Arabella; Marzocchi, Badder; Menasce, Dario; Moroni, Luigi; Paganoni, Marco; Pedrini, Daniele; Ragazzi, Stefano; Redaelli, Nicola; Tabarelli de Fatis, Tommaso; Buontempo, Salvatore; Cavallo, Nicola; Di Guida, Salvatore; Fabozzi, Francesco; Iorio, Alberto Orso Maria; Lista, Luca; Meola, Sabino; Merola, Mario; Paolucci, Pierluigi; Azzi, Patrizia; Bacchetta, Nicola; Bisello, Dario; Branca, Antonio; Carlin, Roberto; Checchia, Paolo; Dorigo, Tommaso; Galanti, Mario; Gasparini, Fabrizio; Gasparini, Ugo; Giubilato, Piero; Gonella, Franco; Gozzelino, Andrea; Kanishchev, Konstantin; Lacaprara, Stefano; Lazzizzera, Ignazio; Margoni, Martino; Meneguzzo, Anna Teresa; Montecassiano, Fabio; Pazzini, Jacopo; Pozzobon, Nicola; Ronchese, Paolo; Simonetto, Franco; Torassa, Ezio; Tosi, Mia; Vanini, Sara; Zotto, Pierluigi; Zucchetta, Alberto; Zumerle, Gianni; Gabusi, Michele; Ratti, Sergio P; Riccardi, Cristina; Salvini, Paola; Vitulo, Paolo; Biasini, Maurizio; Bilei, Gian Mario; Fanò, Livio; Lariccia, Paolo; Mantovani, Giancarlo; Menichelli, Mauro; Romeo, Francesco; Saha, Anirban; Santocchia, Attilio; Spiezia, Aniello; Androsov, Konstantin; Azzurri, Paolo; Bagliesi, Giuseppe; Bernardini, Jacopo; Boccali, Tommaso; Broccolo, Giuseppe; Castaldi, Rino; Ciocci, Maria Agnese; Dell'Orso, Roberto; Donato, Silvio; Fiori, Francesco; Foà, Lorenzo; Giassi, Alessandro; Grippo, Maria Teresa; Kraan, Aafke; Ligabue, Franco; Lomtadze, Teimuraz; Martini, Luca; Messineo, Alberto; Moon, Chang-Seong; Palla, Fabrizio; Rizzi, Andrea; Savoy-Navarro, Aurore; Serban, Alin Titus; Spagnolo, Paolo; Squillacioti, Paola; Tenchini, Roberto; Tonelli, Guido; Venturi, Andrea; Verdini, Piero Giorgio; Vernieri, Caterina; Barone, Luciano; Cavallari, Francesca; Del Re, Daniele; Diemoz, Marcella; Grassi, Marco; Jorda, Clara; Longo, Egidio; Margaroli, Fabrizio; Meridiani, Paolo; Micheli, Francesco; Nourbakhsh, Shervin; Organtini, Giovanni; Paramatti, Riccardo; Rahatlou, Shahram; Rovelli, Chiara; Soffi, Livia; Traczyk, Piotr; Amapane, Nicola; Arcidiacono, Roberta; Argiro, Stefano; Arneodo, Michele; Bellan, Riccardo; Biino, Cristina; Cartiglia, Nicolo; Casasso, Stefano; Costa, Marco; Degano, Alessandro; Demaria, Natale; Finco, Linda; Mariotti, Chiara; Maselli, Silvia; Migliore, Ernesto; Monaco, Vincenzo; Musich, Marco; Obertino, Maria Margherita; Ortona, Giacomo; Pacher, Luca; Pastrone, Nadia; Pelliccioni, Mario; Pinna Angioni, Gian Luca; Potenza, Alberto; Romero, Alessandra; Ruspa, Marta; Sacchi, Roberto; Solano, Ada; Staiano, Amedeo; Tamponi, Umberto; Belforte, Stefano; Candelise, Vieri; Casarsa, Massimo; Cossutti, Fabio; Della Ricca, Giuseppe; Gobbo, Benigno; La Licata, Chiara; Marone, Matteo; Montanino, Damiana; Schizzi, Andrea; Umer, Tomo; Zanetti, Anna; Chang, Sunghyun; Kim, Tae Yeon; Nam, Soon-Kwon; Kim, Dong Hee; Kim, Gui Nyun; Kim, Ji Eun; Kim, Min Suk; Kong, Dae Jung; Lee, Sangeun; Oh, Young Do; Park, Hyangkyu; Sakharov, Alexandre; Son, Dong-Chul; Kim, Jae Yool; Kim, Zero Jaeho; Song, Sanghyeon; Choi, Suyong; Gyun, Dooyeon; Hong, Byung-Sik; Jo, Mihee; Kim, Hyunchul; Kim, Yongsun; Lee, Byounghoon; Lee, Kyong Sei; Park, Sung Keun; Roh, Youn; Choi, Minkyoo; Kim, Ji Hyun; Park, Chawon; Park, Inkyu; Park, Sangnam; Ryu, Geonmo; Choi, Young-Il; Choi, Young Kyu; Goh, Junghwan; Kwon, Eunhyang; Lee, Jongseok; Seo, Hyunkwan; Yu, Intae; Juodagalvis, Andrius; Komaragiri, Jyothsna Rani; Castilla-Valdez, Heriberto; De La Cruz-Burelo, Eduard; Heredia-de La Cruz, Ivan; Lopez-Fernandez, Ricardo; Martínez-Ortega, Jorge; Sánchez Hernández, Alberto; Villasenor-Cendejas, Luis Manuel; Carrillo Moreno, Salvador; Vazquez Valencia, Fabiola; Salazar Ibarguen, Humberto Antonio; Casimiro Linares, Edgar; Morelos Pineda, Antonio; Krofcheck, David; Butler, Philip H; Doesburg, Robert; Reucroft, Steve; Ahmad, Ashfaq; Ahmad, Muhammad; Asghar, Muhammad Irfan; Butt, Jamila; Hassan, Qamar; Hoorani, Hafeez R; Khan, Wajid Ali; Khurshid, Taimoor; Qazi, Shamona; Shah, Mehar Ali; Shoaib, Muhammad; Bialkowska, Helena; Bluj, Michal; Boimska, Bożena; Frueboes, Tomasz; Górski, Maciej; Kazana, Malgorzata; Nawrocki, Krzysztof; Romanowska-Rybinska, Katarzyna; Szleper, Michal; Wrochna, Grzegorz; Zalewski, Piotr; Brona, Grzegorz; Bunkowski, Karol; Cwiok, Mikolaj; Dominik, Wojciech; Doroba, Krzysztof; Kalinowski, Artur; Konecki, Marcin; Krolikowski, Jan; Misiura, Maciej; Wolszczak, Weronika; Bargassa, Pedrame; Beirão Da Cruz E Silva, Cristóvão; Faccioli, Pietro; Ferreira Parracho, Pedro Guilherme; Gallinaro, Michele; Nguyen, Federico; Rodrigues Antunes, Joao; Seixas, Joao; Varela, Joao; Vischia, Pietro; Golutvin, Igor; Gorbunov, Ilya; Karjavin, Vladimir; Konoplyanikov, Viktor; Korenkov, Vladimir; Kozlov, Guennady; Lanev, Alexander; Malakhov, Alexander; Matveev, Viktor; Moisenz, Petr; Palichik, Vladimir; Perelygin, Victor; Savina, Maria; Shmatov, Sergey; Shulha, Siarhei; Skatchkov, Nikolai; Smirnov, Vitaly; Zarubin, Anatoli; Golovtsov, Victor; Ivanov, Yury; Kim, Victor; Levchenko, Petr; Murzin, Victor; Oreshkin, Vadim; Smirnov, Igor; Sulimov, Valentin; Uvarov, Lev; Vavilov, Sergey; Vorobyev, Alexey; Vorobyev, Andrey; Andreev, Yuri; Dermenev, Alexander; Gninenko, Sergei; Golubev, Nikolai; Kirsanov, Mikhail; Krasnikov, Nikolai; Pashenkov, Anatoli; Tlisov, Danila; Toropin, Alexander; Epshteyn, Vladimir; Gavrilov, Vladimir; Lychkovskaya, Natalia; Popov, Vladimir; Safronov, Grigory; Semenov, Sergey; Spiridonov, Alexander; Stolin, Viatcheslav; Vlasov, Evgueni; Zhokin, Alexander; Andreev, Vladimir; Azarkin, Maksim; Dremin, Igor; Kirakosyan, Martin; Leonidov, Andrey; Mesyats, Gennady; Rusakov, Sergey V; Vinogradov, Alexey; Belyaev, Andrey; Boos, Edouard; Dubinin, Mikhail; Dudko, Lev; Ershov, Alexander; Gribushin, Andrey; Klyukhin, Vyacheslav; Kodolova, Olga; Lokhtin, Igor; Obraztsov, Stepan; Perfilov, Maxim; Petrushanko, Sergey; Savrin, Viktor; Azhgirey, Igor; Bayshev, Igor; Bitioukov, Sergei; Kachanov, Vassili; Kalinin, Alexey; Konstantinov, Dmitri; Krychkine, Victor; Petrov, Vladimir; Ryutin, Roman; Sobol, Andrei; Tourtchanovitch, Leonid; Troshin, Sergey; Tyurin, Nikolay; Uzunian, Andrey; Volkov, Alexey; Adzic, Petar; Djordjevic, Milos; Ekmedzic, Marko; Milosevic, Jovan; Aguilar-Benitez, Manuel; Alcaraz Maestre, Juan; Battilana, Carlo; Calvo, Enrique; Cerrada, Marcos; Chamizo Llatas, Maria; Colino, Nicanor; De La Cruz, Begona; Delgado Peris, Antonio; Domínguez Vázquez, Daniel; Fernandez Bedoya, Cristina; Fernández Ramos, Juan Pablo; Ferrando, Antonio; Flix, Jose; Fouz, Maria Cruz; Garcia-Abia, Pablo; Gonzalez Lopez, Oscar; Goy Lopez, Silvia; Hernandez, Jose M; Josa, Maria Isabel; Merino, Gonzalo; Navarro De Martino, Eduardo; Pérez Calero Yzquierdo, Antonio María; Puerta Pelayo, Jesus; Quintario Olmeda, Adrián; Redondo, Ignacio; Romero, Luciano; Soares, Mara Senghi; Willmott, Carlos; Albajar, Carmen; de Trocóniz, Jorge F; Missiroli, Marino; Brun, Hugues; Cuevas, Javier; Fernandez Menendez, Javier; Folgueras, Santiago; Gonzalez Caballero, Isidro; Lloret Iglesias, Lara; Brochero Cifuentes, Javier Andres; Cabrillo, Iban Jose; Calderon, Alicia; Duarte Campderros, Jordi; Fernandez, Marcos; Gomez, Gervasio; Gonzalez Sanchez, Javier; Graziano, Alberto; Lopez Virto, Amparo; Marco, Jesus; Marco, Rafael; Martinez Rivero, Celso; Matorras, Francisco; Munoz Sanchez, Francisca Javiela; Piedra Gomez, Jonatan; Rodrigo, Teresa; Rodríguez-Marrero, Ana Yaiza; Ruiz-Jimeno, Alberto; Scodellaro, Luca; Vila, Ivan; Vilar Cortabitarte, Rocio; Abbaneo, Duccio; Auffray, Etiennette; Auzinger, Georg; Bachtis, Michail; Baillon, Paul; Ball, Austin; Barney, David; Benaglia, Andrea; Bendavid, Joshua; Benhabib, Lamia; Benitez, Jose F; Bernet, Colin; Bianchi, Giovanni; Bloch, Philippe; Bocci, Andrea; Bonato, Alessio; Bondu, Olivier; Botta, Cristina; Breuker, Horst; Camporesi, Tiziano; Cerminara, Gianluca; Christiansen, Tim; Coarasa Perez, Jose Antonio; Colafranceschi, Stefano; D'Alfonso, Mariarosaria; D'Enterria, David; Dabrowski, Anne; David Tinoco Mendes, Andre; De Guio, Federico; De Roeck, Albert; De Visscher, Simon; Dobson, Marc; Dupont-Sagorin, Niels; Elliott-Peisert, Anna; Eugster, Jürg; Franzoni, Giovanni; Funk, Wolfgang; Giffels, Manuel; Gigi, Dominique; Gill, Karl; Girone, Maria; Giunta, Marina; Glege, Frank; Gomez-Reino Garrido, Robert; Gowdy, Stephen; Guida, Roberto; Hammer, Josef; Hansen, Magnus; Harris, Philip; Hegeman, Jeroen; Innocente, Vincenzo; Janot, Patrick; Karavakis, Edward; Kousouris, Konstantinos; Krajczar, Krisztian; Lecoq, Paul; Lourenco, Carlos; Magini, Nicolo; Malgeri, Luca; Mannelli, Marcello; Masetti, Lorenzo; Meijers, Frans; Mersi, Stefano; Meschi, Emilio; Moortgat, Filip; Mulders, Martijn; Musella, Pasquale; Orsini, Luciano; Palencia Cortezon, Enrique; Pape, Luc; Perez, Emmanuelle; Perrozzi, Luca; Petrilli, Achille; Petrucciani, Giovanni; Pfeiffer, Andreas; Pierini, Maurizio; Pimiä, Martti; Piparo, Danilo; Plagge, Michael; Racz, Attila; Reece, William; Rolandi, Gigi; Rovere, Marco; Sakulin, Hannes; Santanastasio, Francesco; Schäfer, Christoph; Schwick, Christoph; Sekmen, Sezen; Sharma, Archana; Siegrist, Patrice; Silva, Pedro; Simon, Michal; Sphicas, Paraskevas; Steggemann, Jan; Stieger, Benjamin; Stoye, Markus; Treille, Daniel; Tsirou, Andromachi; Veres, Gabor Istvan; Vlimant, Jean-Roch; Wöhri, Hermine Katharina; Zeuner, Wolfram Dietrich; Bertl, Willi; Deiters, Konrad; Erdmann, Wolfram; Horisberger, Roland; Ingram, Quentin; Kaestli, Hans-Christian; König, Stefan; Kotlinski, Danek; Langenegger, Urs; Renker, Dieter; Rohe, Tilman; Bachmair, Felix; Bäni, Lukas; Bianchini, Lorenzo; Bortignon, Pierluigi; Buchmann, Marco-Andrea; Casal, Bruno; Chanon, Nicolas; Deisher, Amanda; Dissertori, Günther; Dittmar, Michael; Donegà, Mauro; Dünser, Marc; Eller, Philipp; Grab, Christoph; Hits, Dmitry; Lustermann, Werner; Mangano, Boris; Marini, Andrea Carlo; Martinez Ruiz del Arbol, Pablo; Meister, Daniel; Mohr, Niklas; Nägeli, Christoph; Nef, Pascal; Nessi-Tedaldi, Francesca; Pandolfi, Francesco; Pauss, Felicitas; Peruzzi, Marco; Quittnat, Milena; Rebane, Liis; Ronga, Frederic Jean; Rossini, Marco; Starodumov, Andrei; Takahashi, Maiko; Theofilatos, Konstantinos; Wallny, Rainer; Weber, Hannsjoerg Artur; Amsler, Claude; Canelli, Maria Florencia; Chiochia, Vincenzo; De Cosa, Annapaola; Hinzmann, Andreas; Hreus, Tomas; Ivova Rikova, Mirena; Kilminster, Benjamin; Millan Mejias, Barbara; Ngadiuba, Jennifer; Robmann, Peter; Snoek, Hella; Taroni, Silvia; Verzetti, Mauro; Yang, Yong; Cardaci, Marco; Chen, Kuan-Hsin; Ferro, Cristina; Kuo, Chia-Ming; Li, Syue-Wei; Lin, Willis; Lu, Yun-Ju; Volpe, Roberta; Yu, Shin-Shan; Bartalini, Paolo; Chang, Paoti; Chang, You-Hao; Chang, Yu-Wei; Chao, Yuan; Chen, Kai-Feng; Chen, Po-Hsun; Dietz, Charles; Grundler, Ulysses; Hou, George Wei-Shu; Hsiung, Yee; Kao, Kai-Yi; Lei, Yeong-Jyi; Liu, Yueh-Feng; Lu, Rong-Shyang; Majumder, Devdatta; Petrakou, Eleni; Shi, Xin; Shiu, Jing-Ge; Tzeng, Yeng-Ming; Wang, Minzu; Wilken, Rachel; Asavapibhop, Burin; Suwonjandee, Narumon; Adiguzel, Aytul; Bakirci, Mustafa Numan; Cerci, Salim; Dozen, Candan; Dumanoglu, Isa; Eskut, Eda; Girgis, Semiray; Gokbulut, Gul; Gurpinar, Emine; Hos, Ilknur; Kangal, Evrim Ersin; Kayis Topaksu, Aysel; Onengut, Gulsen; Ozdemir, Kadri; Ozturk, Sertac; Polatoz, Ayse; Sogut, Kenan; Sunar Cerci, Deniz; Tali, Bayram; Topakli, Huseyin; Vergili, Mehmet; Akin, Ilina Vasileva; Aliev, Takhmasib; Bilin, Bugra; Bilmis, Selcuk; Deniz, Muhammed; Gamsizkan, Halil; Guler, Ali Murat; Karapinar, Guler; Ocalan, Kadir; Ozpineci, Altug; Serin, Meltem; Sever, Ramazan; Surat, Ugur Emrah; Yalvac, Metin; Zeyrek, Mehmet; Gülmez, Erhan; Isildak, Bora; Kaya, Mithat; Kaya, Ozlem; Ozkorucuklu, Suat; Bahtiyar, Hüseyin; Barlas, Esra; Cankocak, Kerem; Günaydin, Yusuf Oguzhan; Vardarli, Fuat Ilkehan; Yücel, Mete; Levchuk, Leonid; Sorokin, Pavel; Brooke, James John; Clement, Emyr; Cussans, David; Flacher, Henning; Frazier, Robert; Goldstein, Joel; Grimes, Mark; Heath, Greg P; Heath, Helen F; Jacob, Jeson; Kreczko, Lukasz; Lucas, Chris; Meng, Zhaoxia; Newbold, Dave M; Paramesvaran, Sudarshan; Poll, Anthony; Senkin, Sergey; Smith, Vincent J; Williams, Thomas; Bell, Ken W; Belyaev, Alexander; Brew, Christopher; Brown, Robert M; Cockerill, David JA; Coughlan, John A; Harder, Kristian; Harper, Sam; Ilic, Jelena; Olaiya, Emmanuel; Petyt, David; Shepherd-Themistocleous, Claire; Thea, Alessandro; Tomalin, Ian R; Womersley, William John; Worm, Steven; Baber, Mark; Bainbridge, Robert; Buchmuller, Oliver; Burton, Darren; Colling, David; Cripps, Nicholas; Cutajar, Michael; Dauncey, Paul; Davies, Gavin; Della Negra, Michel; Ferguson, William; Fulcher, Jonathan; Futyan, David; Gilbert, Andrew; Guneratne Bryer, Arlo; Hall, Geoffrey; Hatherell, Zoe; Hays, Jonathan; Iles, Gregory; Jarvis, Martyn; Karapostoli, Georgia; Kenzie, Matthew; Lane, Rebecca; Lucas, Robyn; Lyons, Louis; Magnan, Anne-Marie; Marrouche, Jad; Mathias, Bryn; Nandi, Robin; Nash, Jordan; Nikitenko, Alexander; Pela, Joao; Pesaresi, Mark; Petridis, Konstantinos; Pioppi, Michele; Raymond, David Mark; Rogerson, Samuel; Rose, Andrew; Seez, Christopher; Sharp, Peter; Sparrow, Alex; Tapper, Alexander; Vazquez Acosta, Monica; Virdee, Tejinder; Wakefield, Stuart; Wardle, Nicholas; Cole, Joanne; Hobson, Peter R; Khan, Akram; Kyberd, Paul; Leggat, Duncan; Leslie, Dawn; Martin, William; Reid, Ivan; Symonds, Philip; Teodorescu, Liliana; Turner, Mark; Dittmann, Jay; Hatakeyama, Kenichi; Kasmi, Azeddine; Liu, Hongxuan; Scarborough, Tara; Charaf, Otman; Cooper, Seth; Henderson, Conor; Rumerio, Paolo; Avetisyan, Aram; Bose, Tulika; Fantasia, Cory; Heister, Arno; Lawson, Philip; Lazic, Dragoslav; Richardson, Clint; Rohlf, James; Sperka, David; St John, Jason; Sulak, Lawrence; Alimena, Juliette; Bhattacharya, Saptaparna; Christopher, Grant; Cutts, David; Demiragli, Zeynep; Ferapontov, Alexey; Garabedian, Alex; Heintz, Ulrich; Jabeen, Shabnam; Kukartsev, Gennadiy; Laird, Edward; Landsberg, Greg; Luk, Michael; Narain, Meenakshi; Segala, Michael; Sinthuprasith, Tutanon; Speer, Thomas; Swanson, Joshua; Breedon, Richard; Breto, Guillermo; Calderon De La Barca Sanchez, Manuel; Chauhan, Sushil; Chertok, Maxwell; Conway, John; Conway, Rylan; Cox, Peter Timothy; Erbacher, Robin; Gardner, Michael; Ko, Winston; Kopecky, Alexandra; Lander, Richard; Miceli, Tia; Mulhearn, Michael; Pellett, Dave; Pilot, Justin; Ricci-Tam, Francesca; Rutherford, Britney; Searle, Matthew; Shalhout, Shalhout; Smith, John; Squires, Michael; Tripathi, Mani; Wilbur, Scott; Yohay, Rachel; Andreev, Valeri; Cline, David; Cousins, Robert; Erhan, Samim; Everaerts, Pieter; Farrell, Chris; Felcini, Marta; Hauser, Jay; Ignatenko, Mikhail; Jarvis, Chad; Rakness, Gregory; Takasugi, Eric; Valuev, Vyacheslav; Weber, Matthias; Babb, John; Clare, Robert; Ellison, John Anthony; Gary, J William; Hanson, Gail; Heilman, Jesse; Jandir, Pawandeep; Lacroix, Florent; Liu, Hongliang; Long, Owen Rosser; Luthra, Arun; Malberti, Martina; Nguyen, Harold; Shrinivas, Amithabh; Sturdy, Jared; Sumowidagdo, Suharyo; Wimpenny, Stephen; Andrews, Warren; Branson, James G; Cerati, Giuseppe Benedetto; Cittolin, Sergio; D'Agnolo, Raffaele Tito; Evans, David; Holzner, André; Kelley, Ryan; Kovalskyi, Dmytro; Lebourgeois, Matthew; Letts, James; Macneill, Ian; Padhi, Sanjay; Palmer, Christopher; Pieri, Marco; Sani, Matteo; Sharma, Vivek; Simon, Sean; Sudano, Elizabeth; Tadel, Matevz; Tu, Yanjun; Vartak, Adish; Wasserbaech, Steven; Würthwein, Frank; Yagil, Avraham; Yoo, Jaehyeok; Barge, Derek; Bradmiller-Feld, John; Campagnari, Claudio; Danielson, Thomas; Dishaw, Adam; Flowers, Kristen; Franco Sevilla, Manuel; Geffert, Paul; George, Christopher; Golf, Frank; Incandela, Joe; Justus, Christopher; Magaña Villalba, Ricardo; Mccoll, Nickolas; Pavlunin, Viktor; Richman, Jeffrey; Rossin, Roberto; Stuart, David; To, Wing; West, Christopher; Apresyan, Artur; Bornheim, Adolf; Bunn, Julian; Chen, Yi; Di Marco, Emanuele; Duarte, Javier; Kcira, Dorian; Mott, Alexander; Newman, Harvey B; Pena, Cristian; Rogan, Christopher; Spiropulu, Maria; Timciuc, Vladlen; Wilkinson, Richard; Xie, Si; Zhu, Ren-Yuan; Azzolini, Virginia; Calamba, Aristotle; Carroll, Ryan; Ferguson, Thomas; Iiyama, Yutaro; Jang, Dong Wook; Paulini, Manfred; Russ, James; Vogel, Helmut; Vorobiev, Igor; Cumalat, John Perry; Drell, Brian Robert; Ford, William T; Gaz, Alessandro; Luiggi Lopez, Eduardo; Nauenberg, Uriel; Smith, James; Stenson, Kevin; Ulmer, Keith; Wagner, Stephen Robert; Alexander, James; Chatterjee, Avishek; Chu, Jennifer; Eggert, Nicholas; Gibbons, Lawrence Kent; Hopkins, Walter; Khukhunaishvili, Aleko; Kreis, Benjamin; Mirman, Nathan; Nicolas Kaufman, Gala; Patterson, Juliet Ritchie; Ryd, Anders; Salvati, Emmanuele; Sun, Werner; Teo, Wee Don; Thom, Julia; Thompson, Joshua; Tucker, Jordan; Weng, Yao; Winstrom, Lucas; Wittich, Peter; Winn, Dave; Abdullin, Salavat; Albrow, Michael; Anderson, Jacob; Apollinari, Giorgio; Bauerdick, Lothar AT; Beretvas, Andrew; Berryhill, Jeffrey; Bhat, Pushpalatha C; Burkett, Kevin; Butler, Joel Nathan; Chetluru, Vasundhara; Cheung, Harry; Chlebana, Frank; Cihangir, Selcuk; Elvira, Victor Daniel; Fisk, Ian; Freeman, Jim; Gao, Yanyan; Gottschalk, Erik; Gray, Lindsey; Green, Dan; Grünendahl, Stefan; Gutsche, Oliver; Hare, Daryl; Harris, Robert M; Hirschauer, James; Hooberman, Benjamin; Jindariani, Sergo; Johnson, Marvin; Joshi, Umesh; Kaadze, Ketino; Klima, Boaz; Kwan, Simon; Linacre, Jacob; Lincoln, Don; Lipton, Ron; Liu, Tiehui; Lykken, Joseph; Maeshima, Kaori; Marraffino, John Michael; Martinez Outschoorn, Verena Ingrid; Maruyama, Sho; Mason, David; McBride, Patricia; Mishra, Kalanand; Mrenna, Stephen; Musienko, Yuri; Nahn, Steve; Newman-Holmes, Catherine; O'Dell, Vivian; Prokofyev, Oleg; Ratnikova, Natalia; Sexton-Kennedy, Elizabeth; Sharma, Seema; Soha, Aron; Spalding, William J; Spiegel, Leonard; Taylor, Lucas; Tkaczyk, Slawek; Tran, Nhan Viet; Uplegger, Lorenzo; Vaandering, Eric Wayne; Vidal, Richard; Whitbeck, Andrew; Whitmore, Juliana; Wu, Weimin; Yang, Fan; Yun, Jae Chul; Acosta, Darin; Avery, Paul; Bourilkov, Dimitri; Cheng, Tongguang; Das, Souvik; De Gruttola, Michele; Di Giovanni, Gian Piero; Dobur, Didar; Field, Richard D; Fisher, Matthew; Fu, Yu; Furic, Ivan-Kresimir; Hugon, Justin; Kim, Bockjoo; Konigsberg, Jacobo; Korytov, Andrey; Kropivnitskaya, Anna; Kypreos, Theodore; Low, Jia Fu; Matchev, Konstantin; Milenovic, Predrag; Mitselmakher, Guenakh; Muniz, Lana; Rinkevicius, Aurelijus; Shchutska, Lesya; Skhirtladze, Nikoloz; Snowball, Matthew; Yelton, John; Zakaria, Mohammed; Gaultney, Vanessa; Hewamanage, Samantha; Linn, Stephan; Markowitz, Pete; Martinez, German; Rodriguez, Jorge Luis; Adams, Todd; Askew, Andrew; Bochenek, Joseph; Chen, Jie; Diamond, Brendan; Haas, Jeff; Hagopian, Sharon; Hagopian, Vasken; Johnson, Kurtis F; Prosper, Harrison; Veeraraghavan, Venkatesh; Weinberg, Marc; Baarmand, Marc M; Dorney, Brian; Hohlmann, Marcus; Kalakhety, Himali; Yumiceva, Francisco; Adams, Mark Raymond; Apanasevich, Leonard; Bazterra, Victor Eduardo; Betts, Russell Richard; Bucinskaite, Inga; Cavanaugh, Richard; Evdokimov, Olga; Gauthier, Lucie; Gerber, Cecilia Elena; Hofman, David Jonathan; Khalatyan, Samvel; Kurt, Pelin; Moon, Dong Ho; O'Brien, Christine; Silkworth, Christopher; Turner, Paul; Varelas, Nikos; Akgun, Ugur; Albayrak, Elif Asli; Bilki, Burak; Clarida, Warren; Dilsiz, Kamuran; Duru, Firdevs; Haytmyradov, Maksat; Merlo, Jean-Pierre; Mermerkaya, Hamit; Mestvirishvili, Alexi; Moeller, Anthony; Nachtman, Jane; Ogul, Hasan; Onel, Yasar; Ozok, Ferhat; Penzo, Aldo; Rahmat, Rahmat; Sen, Sercan; Tan, Ping; Tiras, Emrah; Wetzel, James; Yetkin, Taylan; Yi, Kai; Barnett, Bruce Arnold; Blumenfeld, Barry; Bolognesi, Sara; Fehling, David; Gritsan, Andrei; Maksimovic, Petar; Martin, Christopher; Swartz, Morris; Baringer, Philip; Bean, Alice; Benelli, Gabriele; Gray, Julia; Kenny III, Raymond Patrick; Murray, Michael; Noonan, Daniel; Sanders, Stephen; Sekaric, Jadranka; Stringer, Robert; Wang, Quan; Wood, Jeffrey Scott; Barfuss, Anne-Fleur; Chakaberia, Irakli; Ivanov, Andrew; Khalil, Sadia; Makouski, Mikhail; Maravin, Yurii; Saini, Lovedeep Kaur; Shrestha, Shruti; Svintradze, Irakli; Gronberg, Jeffrey; Lange, David; Rebassoo, Finn; Wright, Douglas; Baden, Drew; Calvert, Brian; Eno, Sarah Catherine; Gomez, Jaime; Hadley, Nicholas John; Kellogg, Richard G; Kolberg, Ted; Lu, Ying; Marionneau, Matthieu; Mignerey, Alice; Pedro, Kevin; Skuja, Andris; Temple, Jeffrey; Tonjes, Marguerite; Tonwar, Suresh C; Apyan, Aram; Barbieri, Richard; Bauer, Gerry; Busza, Wit; Cali, Ivan Amos; Chan, Matthew; Di Matteo, Leonardo; Dutta, Valentina; Gomez Ceballos, Guillelmo; Goncharov, Maxim; Gulhan, Doga; Klute, Markus; Lai, Yue Shi; Lee, Yen-Jie; Levin, Andrew; Luckey, Paul David; Ma, Teng; Paus, Christoph; Ralph, Duncan; Roland, Christof; Roland, Gunther; Stephans, George; Stöckli, Fabian; Sumorok, Konstanty; Velicanu, Dragos; Veverka, Jan; Wyslouch, Bolek; Yang, Mingming; Yoon, Sungho; Zanetti, Marco; Zhukova, Victoria; Dahmes, Bryan; De Benedetti, Abraham; Gude, Alexander; Kao, Shih-Chuan; Klapoetke, Kevin; Kubota, Yuichi; Mans, Jeremy; Pastika, Nathaniel; Rusack, Roger; Singovsky, Alexander; Tambe, Norbert; Turkewitz, Jared; Acosta, John Gabriel; Cremaldi, Lucien Marcus; Kroeger, Rob; Oliveros, Sandra; Perera, Lalith; Sanders, David A; Summers, Don; Avdeeva, Ekaterina; Bloom, Kenneth; Bose, Suvadeep; Claes, Daniel R; Dominguez, Aaron; Gonzalez Suarez, Rebeca; Keller, Jason; Knowlton, Dan; Kravchenko, Ilya; Lazo-Flores, Jose; Malik, Sudhir; Meier, Frank; Snow, Gregory R; Dolen, James; Godshalk, Andrew; Iashvili, Ia; Jain, Supriya; Kharchilava, Avto; Kumar, Ashish; Rappoccio, Salvatore; Alverson, George; Barberis, Emanuela; Baumgartel, Darin; Chasco, Matthew; Haley, Joseph; Massironi, Andrea; Nash, David; Orimoto, Toyoko; Trocino, Daniele; Wood, Darien; Zhang, Jinzhong; Anastassov, Anton; Hahn, Kristan Allan; Kubik, Andrew; Lusito, Letizia; Mucia, Nicholas; Odell, Nathaniel; Pollack, Brian; Pozdnyakov, Andrey; Schmitt, Michael; Stoynev, Stoyan; Sung, Kevin; Velasco, Mayda; Won, Steven; Berry, Douglas; Brinkerhoff, Andrew; Chan, Kwok Ming; Drozdetskiy, Alexey; Hildreth, Michael; Jessop, Colin; Karmgard, Daniel John; Kellams, Nathan; Kolb, Jeff; Lannon, Kevin; Luo, Wuming; Lynch, Sean; Marinelli, Nancy; Morse, David Michael; Pearson, Tessa; Planer, Michael; Ruchti, Randy; Slaunwhite, Jason; Valls, Nil; Wayne, Mitchell; Wolf, Matthias; Woodard, Anna; Antonelli, Louis; Bylsma, Ben; Durkin, Lloyd Stanley; Flowers, Sean; Hill, Christopher; Hughes, Richard; Kotov, Khristian; Ling, Ta-Yung; Puigh, Darren; Rodenburg, Marissa; Smith, Geoffrey; Vuosalo, Carl; Winer, Brian L; Wolfe, Homer; Wulsin, Howard Wells; Berry, Edmund; Elmer, Peter; Halyo, Valerie; Hebda, Philip; Hunt, Adam; Jindal, Pratima; Koay, Sue Ann; Lujan, Paul; Marlow, Daniel; Medvedeva, Tatiana; Mooney, Michael; Olsen, James; Piroué, Pierre; Quan, Xiaohang; Raval, Amita; Saka, Halil; Stickland, David; Tully, Christopher; Werner, Jeremy Scott; Zenz, Seth Conrad; Zuranski, Andrzej; Brownson, Eric; Lopez, Angel; Mendez, Hector; Ramirez Vargas, Juan Eduardo; Alagoz, Enver; Benedetti, Daniele; Bolla, Gino; Bortoletto, Daniela; De Mattia, Marco; Everett, Adam; Hu, Zhen; Jha, Manoj; Jones, Matthew; Jung, Kurt; Kress, Matthew; Leonardo, Nuno; Lopes Pegna, David; Maroussov, Vassili; Merkel, Petra; Miller, David Harry; Neumeister, Norbert; Radburn-Smith, Benjamin Charles; Shipsey, Ian; Silvers, David; Svyatkovskiy, Alexey; Wang, Fuqiang; Xie, Wei; Xu, Lingshan; Yoo, Hwi Dong; Zablocki, Jakub; Zheng, Yu; Parashar, Neeti; Adair, Antony; Akgun, Bora; Ecklund, Karl Matthew; Geurts, Frank JM; Li, Wei; Michlin, Benjamin; Padley, Brian Paul; Redjimi, Radia; Roberts, Jay; Zabel, James; Betchart, Burton; Bodek, Arie; Covarelli, Roberto; de Barbaro, Pawel; Demina, Regina; Eshaq, Yossof; Ferbel, Thomas; Garcia-Bellido, Aran; Goldenzweig, Pablo; Han, Jiyeon; Harel, Amnon; Miner, Daniel Carl; Petrillo, Gianluca; Vishnevskiy, Dmitry; Zielinski, Marek; Bhatti, Anwar; Ciesielski, Robert; Demortier, Luc; Goulianos, Konstantin; Lungu, Gheorghe; Malik, Sarah; Mesropian, Christina; Arora, Sanjay; Barker, Anthony; Chou, John Paul; Contreras-Campana, Christian; Contreras-Campana, Emmanuel; Duggan, Daniel; Ferencek, Dinko; Gershtein, Yuri; Gray, Richard; Halkiadakis, Eva; Hidas, Dean; Lath, Amitabh; Panwalkar, Shruti; Park, Michael; Patel, Rishi; Rekovic, Vladimir; Robles, Jorge; Salur, Sevil; Schnetzer, Steve; Seitz, Claudia; Somalwar, Sunil; Stone, Robert; Thomas, Scott; Thomassen, Peter; Walker, Matthew; Rose, Keith; Spanier, Stefan; Yang, Zong-Chang; York, Andrew; Bouhali, Othmane; Eusebi, Ricardo; Flanagan, Will; Gilmore, Jason; Kamon, Teruki; Khotilovich, Vadim; Krutelyov, Vyacheslav; Montalvo, Roy; Osipenkov, Ilya; Pakhotin, Yuriy; Perloff, Alexx; Roe, Jeffrey; Rose, Anthony; Safonov, Alexei; Sakuma, Tai; Suarez, Indara; Tatarinov, Aysen; Toback, David; Akchurin, Nural; Cowden, Christopher; Damgov, Jordan; Dragoiu, Cosmin; Dudero, Phillip Russell; Faulkner, James; Kovitanggoon, Kittikul; Kunori, Shuichi; Lee, Sung Won; Libeiro, Terence; Volobouev, Igor; Appelt, Eric; Delannoy, Andrés G; Greene, Senta; Gurrola, Alfredo; Johns, Willard; Maguire, Charles; Mao, Yaxian; Melo, Andrew; Sharma, Monika; Sheldon, Paul; Snook, Benjamin; Tuo, Shengquan; Velkovska, Julia; Arenton, Michael Wayne; Boutle, Sarah; Cox, Bradley; Francis, Brian; Goodell, Joseph; Hirosky, Robert; Ledovskoy, Alexander; Li, Hengne; Lin, Chuanzhe; Neu, Christopher; Wood, John; Gollapinni, Sowjanya; Harr, Robert; Karchin, Paul Edmund; Kottachchi Kankanamge Don, Chamath; Lamichhane, Pramod; Belknap, Donald; Borrello, Laura; Carlsmith, Duncan; Cepeda, Maria; Dasu, Sridhara; Duric, Senka; Friis, Evan; Grothe, Monika; Hall-Wilton, Richard; Herndon, Matthew; Hervé, Alain; Klabbers, Pamela; Klukas, Jeffrey; Lanaro, Armando; Lazaridis, Christos; Levine, Aaron; Loveless, Richard; Mohapatra, Ajit; Ojalvo, Isabel; Perry, Thomas; Pierro, Giuseppe Antonio; Polese, Giovanni; Ross, Ian; Sarangi, Tapas; Savin, Alexander; Smith, Wesley H; Woods, Nathaniel

    2014-01-01

    The discovery of a new boson with a mass of approximately 125 GeV in 2012 at the LHC has heralded a new era in understanding the nature of electroweak symmetry breaking and possibly completing the standard model of particle physics. Since the first observation in decays to gamma-gamma, WW, and ZZ boson pairs, an extensive set of measurements of the mass and couplings to W and Z bosons, as well as multiple tests of the spin-parity quantum numbers, have revealed that the properties of the new boson are consistent with those of the long-sought agent responsible for electroweak symmetry breaking. An important open question is whether the new particle also couples to fermions, and in particular to down-type fermions, since the current measurements mainly constrain the couplings to the up-type top quark. Determination of the couplings to down-type fermions requires direct measurement of the corresponding Higgs boson decays, as recently reported by the CMS experiment in the study of Higgs decays to bottom quarks and...

  17. On the origins and the historical roots of the Higgs boson research from a bibliometric perspective

    Science.gov (United States)

    Barth, A.; Marx, W.; Bornmann, L.; Mutz, R.

    2014-06-01

    The subject of our present paper is the analysis of the origins or historical roots of the Higgs boson research from a bibliometric perspective, using a segmented regression analysis in combination with a method named reference publication year spectroscopy (RPYS). Our analysis is based on the references cited in the Higgs boson publications published since 1974. The objective of our analysis consists of identifying specific individual publications in the Higgs boson research context to which the scientific community frequently had referred to. We are interested in seminal works which contributed to a high extent to the discovery of the Higgs boson. Our results show that researchers in the Higgs boson field preferably refer to more recently published papers —particularly papers published since the beginning of the sixties. For example, our analysis reveals seven major contributions which appeared within the sixties: Englert and Brout (1964), Higgs (1964, 2 papers), and Guralnik et al. (1964) on the Higgs mechanism as well as Glashow (1961), Weinberg (1967), and Salam (1968) on the unification of weak and electromagnetic interaction. Even if the Nobel Prize award highlights the outstanding importance of the work of Peter Higgs and Francois Englert, bibliometrics offer the additional possibility of getting hints to other publications in this research field (especially to historical publications), which are of vital importance from the expert point of view.

  18. Physics of W bosons at LEP

    CERN Document Server

    Mele, S

    2004-01-01

    The high-energy and high-luminosity data-taking campaigns of the LEP e+e- collider provided the four collaborations, ALEPH, DELPHI, L3 and OPAL, with about 50 000 W-boson pairs and about a thousand singly-produced W bosons. This unique data sample has an unprecedented reach in probing some aspects of the Standard Model of the electroweak interactions, and this article reviews several achievements in the understanding of W-boson physics at LEP. The measurements of the cross sections for W-boson production are discussed, together with their implication on the existence of the coupling between Z and W bosons. The precision measurements of the magnitude of triple gauge-boson couplings are presented. The observation of the longitudinal helicity component of the W-boson spin, related to the mechanism of electroweak symmetry breaking, is described together with the techniques used to probe the CP and CPT symmetries in the W-boson system. A discussion on the intricacies of the measurement of the mass of the W boson, ...

  19. The long journey to the Higgs boson and beyond at the LHC: Emphasis on CMS

    Science.gov (United States)

    Virdee, Tejinder Singh

    2016-11-01

    Since 2010 there has been a rich harvest of results on standard model physics by the ATLAS and CMS experiments operating on the Large Hadron Collider. In the summer of 2012, a spectacular discovery was made by these experiments of a new, heavy particle. All the subsequently analysed data point strongly to the properties of this particle as those expected for the Higgs boson associated with the Brout-Englert-Higgs mechanism postulated to explain the spontaneous symmetry breaking in the electroweak sector, thereby explaining how elementary particles acquire mass. This article focuses on the CMS experiment, the technological challenges encountered in its construction, describing some of the physics results obtained so far, including the discovery of the Higgs boson, and searches for the widely anticipated new physics beyond the standard model, and peer into the future involving the high-luminosity phase of the LHC. This article is complementary to the one by Peter Jenni4 that focuses on the ATLAS experiment.

  20. Phase transitions in Bose-Fermi-Hubbard model in the heavy fermion limit: Hard-core boson approach

    Directory of Open Access Journals (Sweden)

    I.V. Stasyuk

    2015-12-01

    Full Text Available Phase transitions are investigated in the Bose-Fermi-Hubbard model in the mean field and hard-core boson approximations for the case of infinitely small fermion transfer and repulsive on-site boson-fermion interaction. The behavior of the Bose-Einstein condensate order parameter and grand canonical potential is analyzed as functions of the chemical potential of bosons at zero temperature. The possibility of change of order of the phase transition to the superfluid phase in the regime of fixed values of the chemical potentials of Bose- and Fermi-particles is established. The relevant phase diagrams are built.

  1. Transport coefficients from the boson Uehling-Uhlenbeck equation.

    Science.gov (United States)

    Gust, Erich D; Reichl, L E

    2013-04-01

    Expressions for the bulk viscosity, shear viscosity, and thermal conductivity of a quantum degenerate Bose gas above the critical temperature for Bose-Einstein condensation are derived using the Uehling-Uhlenbeck kinetic equation. For contact potentials and hard sphere interactions, the eigenvalues (relaxation rates) of the Uehling-Uhlenbeck collision operator have an upper cutoff. This cutoff requires summation over all discrete eigenvalues and eigenvectors of the collision operator when computing transport coefficients. We numerically compute the shear viscosity and thermal conductivity for any boson gas that interacts via a contact potential. We find that the bulk viscosity of the degenerate boson gas remains identically zero, as it is for the classical gas.

  2. Particles and the universe from the Ionian school to the Higgs boson and beyond

    CERN Document Server

    Narison, Stephan

    2016-01-01

    This book aims to present the history and developments of particle physics from the introduction of the notion of particles by the Ionian school until the discovery of the Higgs boson at LHC in 2012 and discuss the future developments of the field. The evolution of accelerators where different particles have been discovered is reviewed and details about the CERN accelerators are presented. A short presentation of some features of astrophysics and its connection to particle physics is also included.

  3. CKP Hierarchy, Bosonic Tau Function and Bosonization Formulae

    Directory of Open Access Journals (Sweden)

    Johan W. van de Leur

    2012-06-01

    Full Text Available We develop the theory of CKP hierarchy introduced in the papers of Kyoto school [Date E., Jimbo M., Kashiwara M., Miwa T., J. Phys. Soc. Japan 50 (1981, 3806-3812] (see also [Kac V.G., van de Leur J.W., Adv. Ser. Math. Phys., Vol. 7, World Sci. Publ., Teaneck, NJ, 1989, 369-406]. We present appropriate bosonization formulae. We show that in the context of the CKP theory certain orthogonal polynomials appear. These polynomials are polynomial both in even and odd (in Grassmannian sense variables.

  4. CKP Hierarchy, Bosonic Tau Function and Bosonization Formulae

    Science.gov (United States)

    van de Leur, Johan W.; Orlov, Alexander Yu.; Shiota, Takahiro

    2012-06-01

    We develop the theory of CKP hierarchy introduced in the papers of Kyoto school [Date E., Jimbo M., Kashiwara M., Miwa T., J. Phys. Soc. Japan 50 (1981), 3806-3812] (see also [Kac V.G., van de Leur J.W., Adv. Ser. Math. Phys., Vol. 7, World Sci. Publ., Teaneck, NJ, 1989, 369-406]). We present appropriate bosonization formulae. We show that in the context of the CKP theory certain orthogonal polynomials appear. These polynomials are polynomial both in even and odd (in Grassmannian sense) variables.

  5. CKP Hierarchy, Bosonic Tau Function and Bosonization Formulae

    OpenAIRE

    van de Leur, Johan W.; Alexander Yu. Orlov; Takahiro Shiota

    2011-01-01

    We develop the theory of CKP hierarchy introduced in the papers of Kyoto school [Date E., Jimbo M., Kashiwara M., Miwa T., J. Phys. Soc. Japan 50 (1981), 3806-3812] (see also [Kac V.G., van de Leur J.W., Adv. Ser. Math. Phys., Vol. 7, World Sci. Publ., Teaneck, NJ, 1989, 369-406]). We present appropriate bosonization formulae. We show that in the context of the CKP theory certain orthogonal polynomials appear. These polynomials are polynomial both in even and odd (in Grassmannian sense) varia...

  6. Hexatic, Wigner Crystal, and Superfluid Phases of Dipolar Bosons

    OpenAIRE

    Mitra, Kaushik; Williams, C J; de Melo, C. A. R. Sá

    2009-01-01

    The finite temperature phase diagram of two-dimensional dipolar bosons versus dipolar interaction strength is discussed. We identify the stable phases as dipolar superfluid (DSF), dipolar Wigner crystal (DWC), dipolar hexatic fluid (DHF), and dipolar normal fluid (DNF). We also show that other interesting phases like dipolar supersolid (DSS) and dipolar hexatic superfluid (DHSF) are at least metastable, and can potentially be reached by thermal quenching. In particular, for large densities or...

  7. Discovery Mondays

    CERN Multimedia

    2003-01-01

    Many people don't realise quite how much is going on at CERN. Would you like to gain first-hand knowledge of CERN's scientific and technological activities and their many applications? Try out some experiments for yourself, or pick the brains of the people in charge? If so, then the «Lundis Découverte» or Discovery Mondays, will be right up your street. Starting on May 5th, on every first Monday of the month you will be introduced to a different facet of the Laboratory. CERN staff, non-scientists, and members of the general public, everyone is welcome. So tell your friends and neighbours and make sure you don't miss this opportunity to satisfy your curiosity and enjoy yourself at the same time. You won't have to listen to a lecture, as the idea is to have open exchange with the expert in question and for each subject to be illustrated with experiments and demonstrations. There's no need to book, as Microcosm, CERN's interactive museum, will be open non-stop from 7.30 p.m. to 9 p.m. On the first Discovery M...

  8. Quantum distillation of bosons

    Science.gov (United States)

    Weiss, David

    2015-05-01

    The non-equilibrium dynamics of many-body quantum systems present a series of challenges for theory and opportunities for cold atom experiments. I will describe an experiment in which a bundle of initially trapped superfluid 1D Bose lattice gases is quenched to an untrapped, flat lattice potential. This simple experimental situation in the intermediate coupling regime (U/J between 4 and 9.6) leads to interesting dynamics. These include the progressive dissolution of a fraction of the doublons, as well as the quantum distillation and long term confinement of singlons out of and within the central, doublon-dominated region. We measure these processes by combining absorption imaging, photoassociation and 3-body loss to separately reconstruct the spatial distributions of the expectation values of singlons, doublons and triplons. The qualitative dynamics is reproduced by a Gutzwiller mean field model and the essence of the experiment can be understood by considering simple spatial pictures of site occupancies. This work was supported by the NSF and the ARO.

  9. Models of rotating boson stars and geodesics around them: New type of orbits

    Science.gov (United States)

    Grandclément, Philippe; Somé, Claire; Gourgoulhon, Eric

    2014-07-01

    We have developed a highly accurate numerical code capable of solving the coupled Einstein-Klein-Gordon system, in order to construct rotating boson stars in general relativity. Free fields and self-interacting fields, with quartic and sextic potentials, are considered. In particular, we present the first numerical solutions of rotating boson stars with rotational quantum number k=3 and k=4, as well as the first determination of the maximum mass of free-field boson stars with k=2. We have also investigated timelike geodesics in the spacetime generated by a rotating boson star for k=1, 2 and 3. A numerical integration of the geodesic equation has enabled us to identify a peculiar type of orbit: the zero-angular-momentum ones. These orbits pass very close to the center and are qualitatively different from orbits around a Kerr black hole. Should such orbits be observed, they would put stringent constraints on astrophysical compact objects like the Galactic center.

  10. Models of rotating boson stars and geodesics around them: new type of orbits

    CERN Document Server

    Grandclement, Philippe; Gourgoulhon, Eric

    2014-01-01

    We have developed a highly accurate numerical code capable of solving the coupled Einstein-Klein-Gordon system, in order to construct rotating boson stars in general relativity. Free fields and self-interacting fields, with quartic and sextic potentials, are considered. In particular, we present the first numerical solutions of rotating boson stars with rotational quantum number $k=3$ and $k=4$, as well as the first determination of the maximum mass of free-field boson stars with $k=2$. We have also investigated timelike geodesics in the spacetime generated by a rotating boson star for $k=1$, $2$ and $3$. A numerical integration of the geodesic equation has enabled us to identify a peculiar type of orbits: the zero-angular-momentum ones. These orbits pass very close to the center and are qualitatively different from orbits around a Kerr black hole. Should such orbits be observed, they would put stringent constraints on astrophysical compact objects like the Galactic center.

  11. Ayurvedic drug discovery.

    Science.gov (United States)

    Balachandran, Premalatha; Govindarajan, Rajgopal

    2007-12-01

    Ayurveda is a major traditional system of Indian medicine that is still being successfully used in many countries. Recapitulation and adaptation of the older science to modern drug discovery processes can bring renewed interest to the pharmaceutical world and offer unique therapeutic solutions for a wide range of human disorders. Eventhough time-tested evidences vouch immense therapeutic benefits for ayurvedic herbs and formulations, several important issues are required to be resolved for successful implementation of ayurvedic principles to present drug discovery methodologies. Additionally, clinical examination in the extent of efficacy, safety and drug interactions of newly developed ayurvedic drugs and formulations are required to be carefully evaluated. Ayurvedic experts suggest a reverse-pharmacology approach focusing on the potential targets for which ayurvedic herbs and herbal products could bring tremendous leads to ayurvedic drug discovery. Although several novel leads and drug molecules have already been discovered from ayurvedic medicinal herbs, further scientific explorations in this arena along with customization of present technologies to ayurvedic drug manufacturing principles would greatly facilitate a standardized ayurvedic drug discovery.

  12. Higgs boson couplings: measurements and theoretical interpretation

    CERN Document Server

    Mariotti, Chiara

    2016-01-01

    This report will review the Higgs boson properties: the mass, the total width and the couplings to fermions and bosons. The measurements have been performed with the data collected in 2011 and 2012 at the LHC accelerator at CERN by the ATLAS and CMS experiments. Theoretical frameworks to search for new physics are also introduced and discussed.

  13. The study of the W boson

    CERN Document Server

    Buchmüller, O L; Thompson, J C

    2002-01-01

    the status of the measurement of the W boson mass at LEP-2 is reviewed. Properties of the W such as branching ration into quarks and leptons and couplings to other neutral gauge bosons are reported. 4-fermion production cross-sections in e sup + e sup - collisions are also presented. (authors)

  14. Goldstone Bosons as Fractional Cosmic Neutrinos

    CERN Document Server

    Weinberg, Steven

    2013-01-01

    It is suggested that Goldstone bosons may be masquerading as fractional cosmic neutrinos, contributing about 0.39 to what is reported as the effective number of neutrino types in the era before recombination. The broken symmetry associated with these Goldstone bosons is further speculated to be the conservation of the particles of dark matter.

  15. Bosonization of supersymmetric KdV equation

    Energy Technology Data Exchange (ETDEWEB)

    Gao Xiaonan [Department of Physics, Shanghai Jiao Tong University, Shanghai, 200240 (China); Lou, S.Y., E-mail: sylou@sjtu.edu.cn [Department of Physics, Shanghai Jiao Tong University, Shanghai, 200240 (China); Faculty of Science, Ningbo University, Ningbo, 315211 (China); School of Mathematics, Fudan University, Shanghai, 200433 (China)

    2012-01-16

    Bosonization approach to the classical supersymmetric systems is presented. By introducing the multi-fermionic parameters in the expansions of the superfields, the N=1 supersymmetric KdV (sKdV) system is transformed to a system of coupled bosonic equations. The method can be applied to any fermionic systems. By solving the coupled bosonic equations, some novel types of exact solutions can be explicitly obtained. Especially, the richness of the localized excitations of the supersymmetric integrable system is discovered. The rich multi-soliton solutions obtained here have not yet been obtained by using other methods. However, the traditional known multi-soliton solutions can also not be obtained by the bosonization approach of this Letter. Some open problems on the bosonization of the supersymmetric integrable models are proposed in the both classical and quantum levels.

  16. Boson Sampling for Molecular Vibronic Spectra

    CERN Document Server

    Huh, Joonsuk; Peropadre, Borja; McClean, Jarrod R; Aspuru-Guzik, Alán

    2014-01-01

    Quantum computers are expected to be more efficient in performing certain computations than any classical machine. Unfortunately, the technological challenges associated with building a full-scale quantum computer have not yet allowed the experimental verification of such an expectation. Recently, boson sampling has emerged as a problem that is suspected to be intractable on any classical computer, but efficiently implementable with a linear quantum optical setup. Therefore, boson sampling may offer an experimentally realizable challenge to the Extended Church-Turing thesis and this remarkable possibility motivated much of the interest around boson sampling, at least in relation to complexity-theoretic questions. In this work, we show that the successful development of a boson sampling apparatus would not only answer such inquiries, but also yield a practical tool for difficult molecular computations. Specifically, we show that a boson sampling device with a modified input state can be used to generate molecu...

  17. Di-boson results at ATLAS

    Directory of Open Access Journals (Sweden)

    Giraud Pierre-François

    2012-06-01

    Full Text Available Pairs of gauge boson produced in proton-proton collisions at a center-of-mass energy √s of 7 TeV are reconstructed with the ATLAS detector in their leptonic final states. Based on samples of integrated luminosity See PDF mathcal{L} = 1.0 fb−1 (for WW, WZ and ZZ and 35 pb−1 (for Wγ and Zγ of 2011 and 2010 LHC data, the total di-boson production cross sections are measured. They are found, together with the kinematic distributions of the selected di-boson systems to be compatible with the expectation from the Standard Model. The di-boson production also gives a handle on possible anomalous triple gauge boson couplings, for which 95% confidence limits are set.

  18. Universal physics of three bosons with isospin

    CERN Document Server

    Hyodo, Tetsuo; Nishida, Yusuke

    2013-01-01

    We show that there exist two types of universal phenomena for three-boson systems with isospin degrees of freedom. In the isospin symmetric limit, there is only one universal three-boson bound state with the total isospin one, whose binding energy is proportional to that of the two-boson bound state. With large isospin symmetry breaking, the standard Efimov states of three identical bosons appear at low energies. Both phenomena can be realized by three pions with the pion mass appropriately tuned in lattice QCD simulations, or by spin-one bosons in cold atom experiments. Implication to the in-medium softening of multi-pion states is also discussed.

  19. Search for new heavy charged gauge bosons

    Energy Technology Data Exchange (ETDEWEB)

    Magass, Carsten Martin [RWTH Aachen Univ. (Germany)

    2007-11-02

    Additional gauge bosons are introduced in many theoretical extensions to the Standard Model. A search for a new heavy charged gauge boson W' decaying into an electron and a neutrino is presented. The data used in this analysis was taken with the D0 detector at the Fermilab proton-antiproton collider at a center-of-mass energy of 1.96 TeV and corresponds to an integrated luminosity of about 1 fb-1. Since no significant excess is observed in the data, an upper limit is set on the production cross section times branching fraction σW'xBr (W' → ev). Using this limit, a W' boson with mass below ~1 TeV can be excluded at the 95% confidence level assuming that the new boson has the same couplings to fermions as the Standard Model W boson.

  20. Chiral bosonization for non-commutative fields

    CERN Document Server

    Das, A; Méndez, F; López-Sarrion, J; Das, Ashok; Gamboa, Jorge; M\\'endez, Fernando; L\\'opez-Sarri\\'on, Justo

    2004-01-01

    A model of chiral bosons on a non-commutative field space is constructed and new generalized bosonization (fermionization) rules for these fields are given. The conformal structure of the theory is characterized by a level of the Kac-Moody algebra equal to $(1+ \\theta^2)$ where $\\theta$ is the non-commutativity parameter and chiral bosons living in a non-commutative fields space are described by a rational conformal field theory with the central charge of the Virasoro algebra equal to 1. The non-commutative chiral bosons are shown to correspond to a free fermion moving with a speed equal to $ c^{\\prime} = c \\sqrt{1+\\theta^2} $ where $c$ is the speed of light. Lorentz invariance remains intact if $c$ is rescaled by $c \\to c^{\\prime}$. The dispersion relation for bosons and fermions, in this case, is given by $\\omega = c^{\\prime} | k|$.

  1. Thermostatistics of bosonic and fermionic Fibonacci oscillators

    Science.gov (United States)

    Algin, Abdullah; Arik, Metin; Senay, Mustafa; Topcu, Gozde

    2017-01-01

    In this work, we first introduce some new properties concerning the Fibonacci calculus. We then discuss the thermostatistics of gas models of two-parameter deformed oscillators, called bosonic and fermionic Fibonacci oscillators, in the thermodynamical limit. In this framework, we analyze the behavior of two-parameter deformed mean occupation numbers describing the Fibonacci-type bosonic and fermionic intermediate-statistics particles. A virial expansion of the equation of state for the bosonic Fibonacci oscillators’ gas model is obtained in both two and three dimensions, and the first five virial coefficients are derived in terms of the real independent deformation parameters p and q. The effect of bosonic and fermionic p, q-deformation on the thermostatistical properties of Fibonacci-type p, q-boson and p, q-fermion gas models are also discussed. The results obtained in this work can be useful for investigating some exotic quasiparticle states encountered in condensed matter systems.

  2. Search for the Standard Model Higgs Boson in Hadronic $\\tau^{+}\\tau^{-}$ Decays with the ATLAS Detector

    CERN Document Server

    Zanzi, Daniele; Kortner, Sandra

    The discovery of a Higgs boson in di-boson decays, the evidence of its decays into fermion pairs and the compatibility of its measured properties with the Standard Model predictions support the electroweak symmetry breaking mechanism of the Standard Model. The topic of this thesis is the search for the Higgs boson decays into a pair of $\\tau$ leptons, important for probing the coupling of the Higgs boson to fermions. The search is performed in final states where both $\\tau$ leptons decay hadronically using $4.6\\,\\rm{fb}^{-1}$ and $20.3\\,\\rm{fb}^{-1}$ of data collected by the ATLAS detector in proton-proton collisions at the Large Hadron Collider at center-of-mass energies of 7 and 8 TeV, respectively. The signal selection is optimised for events with highly boosted Higgs bosons produced via gluon fusion with additional jet or via vector boson fusion. In order to reduce systematic uncertainties, the major background contributions from $Z\\to\\tau\\tau$ and multi-jet production processes have been measured using s...

  3. Higgs-like boson at 750 GeV and genesis of baryons

    Science.gov (United States)

    Davoudiasl, Hooman; Giardino, Pier Paolo; Zhang, Cen

    2016-07-01

    We propose that the diphoton excess at 750 GeV reported by ATLAS and CMS is due to the decay of an exo-Higgs scalar η associated with the breaking of a new S U (2 )e symmetry, dubbed exo-spin. New fermions, exo-quarks and exo-leptons, get TeV-scale masses through Yukawa couplings with η and generate its couplings to gluons and photons at one loop. The matter content of our model yields a B -L anomaly under S U (2 )e, whose breaking we assume entails a first-order phase transition. A nontrivial B -L asymmetry may therefore be generated in the early Universe, potentially providing a baryogenesis mechanism through the Standard Model (SM) sphaleron processes. The spontaneous breaking of S U (2 )e can, in principle, directly lead to electroweak symmetry breaking, thereby accounting for the proximity of the mass scales of the SM Higgs and the exo-Higgs. Our model can be distinguished from those comprising a singlet scalar and vector fermions by the discovery of TeV scale exo-vector bosons, corresponding to the broken S U (2 )e generators, at the LHC.

  4. The Higgs boson resonance from a chiral Higgs-Yukawa model on the lattice

    Energy Technology Data Exchange (ETDEWEB)

    Kallarackal, Jim

    2011-04-28

    upper and lower Higgs boson mass bound is studied. All numerical results presented in this work involve extensive finite volume analysis. In particular the Higgs boson mass significantly depends on the lattice volume and thus an extrapolation to infinite volume is inevitable. Both mass bounds are revised in the presence of a quark doublet with a mass around 700 GeV. The upper bound of the Higgs boson mass is only slightly enhanced by about 200 GeV with respect to the standard model. The lower bound however, is altered significantly by a factor of about five to ten. The strong dependence of the lower mass bound on the quark mass motivated to explore the Higgs boson mass bounds at a fixed cut off of 1500 GeV and varying quark masses. Preliminary data for the upper Higgs boson mass are presented. A detailed analysis at strong Yukawa couplings of both, the lower and the upper, mass bounds in a non perturbative fashion is certainly needed and may provide a reliable basis in favour or disfavour of a potential fourth generation of heavy quarks. (orig.)

  5. Measuring rare and exclusive Higgs boson decays into light resonances

    Science.gov (United States)

    Chisholm, Andrew S.; Kuttimalai, Silvan; Nikolopoulos, Konstantinos; Spannowsky, Michael

    2016-09-01

    We evaluate the LHC's potential of observing Higgs boson decays into light elementary or composite resonances through their hadronic decay channels. We focus on the Higgs boson production processes with the largest cross sections, pp → h and pp → h+{jet}, with subsequent decays h → ZA or h → Z η _c, and comment on the production process pp → hZ. By exploiting track-based jet substructure observables and extrapolating to 3000 {fb}^{-1} we find {BR}(h → ZA) ≃ {BR}(h → Z η _c) ≲ 0.02 at 95 % CL. We interpret this limit in terms of the 2HDM Type 1. We find that searches for h→ ZA are complementary to existing measurements and can constrain large parts of the currently allowed parameter space.

  6. Measuring rare and exclusive Higgs boson decays into light resonances

    CERN Document Server

    Chisholm, Andrew S; Nikolopoulos, Konstantinos; Spannowsky, Michael

    2016-01-01

    We evaluate the LHC's potential of observing Higgs boson decays into light elementary or composite resonances through their hadronic decay channels. We focus on the Higgs boson production processes with the largest cross sections, $pp\\to h$ and $pp\\to h+\\mathrm{jet}$, with subsequent decays $h \\to ZA$ or $h\\to Z\\,\\eta_c$, and comment on the production process $pp\\to hZ$. By exploiting track-based jet substructure observables and extrapolating to $3000~\\mathrm{fb}^{-1}$ we find ${\\cal BR}(h \\to ZA) \\simeq {\\cal BR}(h \\to Z \\eta_c) \\lesssim 0.02$ at 95% CL. We interpret this limit in terms of the 2HDM Type 1. We find that searches for $h\\to ZA$ are complementary to existing measurements and can constrain large parts of the currently allowed parameter space.

  7. Mean field limit for bosons and propagation of Wigner measures

    CERN Document Server

    Ammari, Z

    2008-01-01

    We consider the N-body Schr\\"{o}dinger dynamics of bosons in the mean field limit with a bounded pair-interaction potential. According to the previous work \\cite{AmNi}, the mean field limit is translated into a semiclassical problem with a small parameter $\\epsilon\\to 0$, after introducing an $\\epsilon$-dependent bosonic quantization. The limit is expressed as a push-forward by a nonlinear flow (e.g. Hartree) of the associated Wigner measures. These object and their basic properties were introduced in \\cite{AmNi} in the infinite dimensional setting. The additional result presented here states that the transport by the nonlinear flow holds for rather general class of quantum states in their mean field limit.

  8. Measuring rare and exclusive Higgs boson decays into light resonances

    Energy Technology Data Exchange (ETDEWEB)

    Chisholm, Andrew S.; Nikolopoulos, Konstantinos [University of Birmingham, School of Physics and Astronomy, Birmingham (United Kingdom); Kuttimalai, Silvan; Spannowsky, Michael [Durham University, Institute for Particle Physics Phenomenology, Department of Physics, Durham (United Kingdom)

    2016-09-15

    We evaluate the LHC's potential of observing Higgs boson decays into light elementary or composite resonances through their hadronic decay channels. We focus on the Higgs boson production processes with the largest cross sections, pp → h and pp → h + jet, with subsequent decays h → ZA or h → Zη{sub c}, and comment on the production process pp → hZ. By exploiting track-based jet substructure observables and extrapolating to 3000 fb{sup -1} we find BR(h → ZA) ≅ BR(h → Zη{sub c})

  9. Discovery of novel enzymes with industrial potential from a cold and alkaline environment by a combination of functional metagenomics and culturing

    DEFF Research Database (Denmark)

    Vester, Jan Kjølhede; Glaring, Mikkel Andreas; Stougaard, Peter

    2014-01-01

    Background: The use of cold-active enzymes has many advantages, including reduced energy consumption and easy inactivation. The ikaite columns of SW Greenland are permanently cold (4-6°C) and alkaline (above pH 10), and the microorganisms living there and their enzymes are adapted...... to these conditions. Since only a small fraction of the total microbial diversity can be cultured in the laboratory, a combined approach involving functional screening of a strain collection and a metagenomic library was undertaken for discovery of novel enzymes from the ikaite columns.Results: A strain collection...... with 322 cultured isolates was screened for enzymatic activities identifying a large number of enzyme producers, with a high re-discovery rate to previously characterized strains. A functional expression library established in Escherichia coli identified a number of novel cold-active enzymes. Both α...

  10. Chronicles in drug discovery.

    Science.gov (United States)

    Davies, Shelley L; Moral, Maria Angels; Bozzo, Jordi

    2007-03-01

    Chronicles in Drug Discovery features special interest reports on advances in drug discovery. This month we highlight agents that target and deplete immunosuppressive regulatory T cells, which are produced by tumor cells to hinder innate immunity against, or chemotherapies targeting, tumor-associated antigens. Antiviral treatments for respiratory syncytial virus, a severe and prevalent infection in children, are limited due to their side effect profiles and cost. New strategies currently under clinical development include monoclonal antibodies, siRNAs, vaccines and oral small molecule inhibitors. Recent therapeutic lines for Huntington's disease include gene therapies that target the mutated human huntingtin gene or deliver neuroprotective growth factors and cellular transplantation in apoptotic regions of the brain. Finally, we highlight the antiinflammatory and antinociceptive properties of new compounds targeting the somatostatin receptor subtype sst4, which warrant further study for their potential application as clinical analgesics.

  11. Neutrino Jets from High-Mass $W_R$ Gauge Bosons in TeV-Scale Left-Right Symmetric Models

    CERN Document Server

    Mitra, Manimala; Scott, Darren J; Spannowsky, Michael

    2016-01-01

    We re-examine the discovery potential at hadron colliders of high-mass right-handed (RH) gauge bosons $W_R$ - an inherent ingredient of Left-Right Symmetric Models (LRSM). We focus on the regime where the $W_R$ is very heavy compared to the heavy Majorana neutrino $N$, and investigate an alternative signature for $W_R \\rightarrow N$ decays. The produced neutrinos are highly boosted in this mass regime. Subsequently, their decays via off-shell $W_R$ bosons to jets, i.e., $N \\rightarrow \\ell^\\pm j j$ are highly collimated, forming a single neutrino jet $(j_N)$. The final-state collider signature is then $\\ell^\\pm j_N$, instead of the widely studied $\\ell^\\pm\\ell^\\pm jj$. Present search strategies are not sensitive to this hierarchical mass regime due to the breakdown of the collider signature definition. We take into account QCD corrections beyond next-to-leading order (NLO) that are important for high-mass Drell-Yan processes at the 13 TeV Large Hadron Collider (LHC). For the first time, we evaluate $W_R$ prod...

  12. Collective Interference of Composite Two-Fermion Bosons

    DEFF Research Database (Denmark)

    Tichy, Malte; Bouvrie, Peter Alexander; Mølmer, Klaus

    2012-01-01

    The composite character of two-fermion bosons manifests itself in the interference of many composites as a deviation from the ideal bosonic behavior. A state of many composite bosons can be represented as a superposition of different numbers of perfect bosons and fermions, which allows us to prov...

  13. Strong correlations in bosons and fermions

    Science.gov (United States)

    Tilahun, Dagim

    If there is a general theme to this thesis, it is the effects of strong correlations in both bosons and fermions. The bosonic system considered here consists of ultracold alkali atoms trapped by interfering lasers, so called optical lattices. Strong interactions, realized by increasing the depth of the lattice potential, or through the phenomenon of Feshbach resonances induce strong correlations amongst the atoms, rendering attempts to describe the systems in terms of single particle type physics unsuccessful. Of course strong correlations are not the exclusive domain of bosons, and also are not caused only by strong interactions. Other factors such as reduced dimensionality, in one-dimensional electron gases, or strong magnetic fields, in two-dimensional electron gases are known to induce strong correlations. In this thesis, we explore the manifestations of strong correlations in ultracold atoms in optical lattices and interacting electron gases. Optical lattices provide a near-perfect realization of lattice models, such as the bosonic Hubbard model (BHM) that have been formulated to study solid state systems. This follows from the absence of defects or impurities that usually plague real solid state systems. Another novel feature of optical lattices is the unprecedented control experimenters have in tuning the different lattice parameters, such as the lattice spacing and the intensity of the lasers. This control enables one to study the model Hamiltonians over a wide range of variables, such as the interaction strength between the atoms, thereby opening the door towards the observation of diverse and interesting phenomena. The BHM, and also its variants, predict various quantum phases, such as the strongly correlated Mott insulator (MI) phase that appears as a function of the parameter t/U, the ratio of the nearest neighbor hopping amplitude to the on-site interaction, which one varies experimentally over a wide range of values simply by switching the intensity

  14. Search for doubly charged Higgs bosons through VBF at the LHC, and beyond

    CERN Document Server

    Bambhaniya, G; Gluza, J; Jelinski, T; Szafron, R

    2015-01-01

    Production and decays of doubly charged Higgs bosons at the LHC and future hadron colliders triggered by vector boson fusion mechanism are discussed in the context of the Minimal Left-Right Symmetric Model. Our analysis is based on the Higgs boson mass spectrum compatible with available constraints which include FCNC effects and vacuum stability of the scalar potential. Though the parity breaking scale $v_R$ is large ($\\sim$ few TeV) and scalar masses which contribute to FCNC effects are even larger, consistent Higgs boson mass spectrum still allows us to keep doubly charged scalar masses below 1 TeV which is an interesting situation for LHC and future FCC colliders. We have shown that allowed Higgs bosons mass spectrum constrains the splittings ($M_{H_{1}^{\\pm \\pm}}-M_{H_{1}^\\pm}$), closing the possibility of $H_{1}^{\\pm\\pm}\\to W_{1}^\\pm H_{1}^\\pm$ decays. Assuming that doubly charged Higgs bosons decay predominantly into a pair of same sign charged leptons through the process $p p \\rightarrow H_{1/2}^{\\pm \\...

  15. Composite Weak Bosons at the Large Hadronic Collider

    Science.gov (United States)

    Fritzsch, Harald

    In a composite model of the weak bosons the p-wave bosons are studied. The state with the lowest mass is identified with the boson, which has been discovered at the LHC. Specific properties of the excited bosons are discussed, in particular their decays into weak bosons and photons. Recently a two-photon signal has been observed, which might come from the decay of a neutral heavy boson with a mass of about 0.75 TeV. This particle could be an excited weak tensor boson.

  16. Higgs boson: near the end of the quest; Boson de Higgs: la physique proche du Graal

    Energy Technology Data Exchange (ETDEWEB)

    Khalatbari, A.

    2012-01-15

    The 2 experiments ATLAS and CMS that look for the existence of the Higgs boson at the LHC, published their last results in end 2011. Both teams announced very strong hints for a Higgs boson with a mass around 125 GeV. The detection of the Higgs boson is based on the identification of the particles produced in its decay and the difficulty is that the decay scheme of the Higgs depends strongly on its mass. For instance, a Higgs boson with a mass of 115 GeV has a probability rate of 70% to decay into a pair of bottom quarks while a mass of 160 GeV will produce pairs of W bosons with a probability rate of 90%. A Higgs boson with a mass of 125 GeV fits well theories beyond the standard model like supersymmetry. (A.C.)

  17. Search for a Higgs Boson Decaying to Weak Boson Pairs at LEP

    CERN Document Server

    Achard, P; Aguilar-Benítez, M; Alcaraz, J; Alemanni, G; Allaby, James V; Aloisio, A; Alviggi, M G; Anderhub, H; Andreev, V P; Anselmo, F; Arefev, A; Azemoon, T; Aziz, T; Bagnaia, P; Bajo, A; Baksay, G; Baksay, L; Baldew, S V; Banerjee, S; Banerjee, Sw; Barczyk, A; Barillère, R; Bartalini, P; Basile, M; Batalova, N; Battiston, R; Bay, A; Becattini, F; Becker, U; Behner, F; Bellucci, L; Berbeco, R; Berdugo, J; Berges, P; Bertucci, B; Betev, B L; Biasini, M; Biglietti, M; Biland, A; Blaising, J J; Blyth, S C; Bobbink, Gerjan J; Böhm, A; Boldizsar, L; Borgia, B; Bottai, S; Bourilkov, D; Bourquin, Maurice; Braccini, S; Branson, J G; Brochu, F; Burger, J D; Burger, W J; Cai, X D; Capell, M; Cara Romeo, G; Carlino, G; Cartacci, A M; Casaus, J; Cavallari, F; Cavallo, N; Cecchi, C; Cerrada, M; Chamizo-Llatas, M; Chang, Y H; Chemarin, M; Chen, A; Chen, G; Chen, G M; Chen, H F; Chen, H S; Chiefari, G; Cifarelli, Luisa; Cindolo, F; Clare, I; Clare, R; Coignet, G; Colino, N; Costantini, S; de la Cruz, B; Cucciarelli, S; van Dalen, J A; De Asmundis, R; Déglon, P L; Debreczeni, J; Degré, A; Dehmelt, K; Deiters, K; Della Volpe, D; Delmeire, E; Denes, P; De Notaristefani, F; De Salvo, A; Diemoz, M; Dierckxsens, M; Dionisi, C; Dittmar, M; Doria, A; Dova, M T; Duchesneau, D; Duda, M; Echenard, B; Eline, A; El-Hage, A; El-Mamouni, H; Engler, A; Eppling, F J; Extermann, P; Falagán, M A; Falciano, S; Favara, A; Fay, J; Fedin, O; Felcini, M; Ferguson, T; Fesefeldt, H S; Fiandrini, E; Field, J H; Filthaut, Frank; Fisher, P H; Fisher, W; Fisk, I; Forconi, G; Freudenreich, Klaus; Furetta, C; Galaktionov, Yu; Ganguli, S N; García-Abia, P; Gataullin, M; Gentile, S; Giagu, S; Gong, Z F; Grenier, G; Grimm, O; Grünewald, M W; Guida, M; van Gulik, R; Gupta, V K; Gurtu, A; Gutay, L J; Haas, D; Hakobyan, R S; Hatzifotiadou, D; Hebbeker, T; Hervé, A; Hirschfelder, J; Hofer, H; Hohlmann, M; Holzner, G; Hou, S R; Hu, Y; Jin, B N; Jones, L W; de Jong, P; Josa-Mutuberria, I; Käfer, D; Kaur, M; Kienzle-Focacci, M N; Kim, J K; Kirkby, Jasper; Kittel, E W; Klimentov, A; König, A C; Kopal, M; Koutsenko, V F; Kräber, M H; Krämer, R W; Krüger, A; Kunin, A; Ladrón de Guevara, P; Laktineh, I; Landi, G; Lebeau, M; Lebedev, A; Lebrun, P; Lecomte, P; Lecoq, P; Le Coultre, P; Le Goff, J M; Leiste, R; Levtchenko, M; Levchenko, P M; Li, C; Likhoded, S; Lin, C H; Lin, W T; Linde, Frank L; Lista, L; Liu, Z A; Lohmann, W; Longo, E; Lü, Y S; Luci, C; Luminari, L; Lustermann, W; Ma Wen Gan; Malgeri, L; Malinin, A; Maña, C; Mangeol, D J J; Mans, J; Martin, J P; Marzano, F; Mazumdar, K; McNeil, R R; Mele, S; Merola, L; Meschini, M; Metzger, W J; Mihul, A; Milcent, H; Mirabelli, G; Mnich, J; Mohanty, G B; Muanza, G S; Muijs, A J M; Musicar, B; Musy, M; Nagy, S; Natale, S; Napolitano, M; Nessi-Tedaldi, F; Newman, H; Nisati, A; Nowak, H; Ofierzynski, R A; Organtini, G; Palomares, C; Paolucci, P; Paramatti, R; Passaleva, G; Patricelli, S; Paul, T; Pauluzzi, M; Paus, C; Pauss, Felicitas; Pedace, M; Pensotti, S; Perret-Gallix, D; Petersen, B; Piccolo, D; Pierella, F; Pioppi, M; Piroué, P A; Pistolesi, E; Plyaskin, V; Pohl, M; Pozhidaev, V; Pothier, J; Prokofiev, D O; Prokofev, D; Quartieri, J; Rahal-Callot, G; Rahaman, M A; Raics, P; Raja, N; Ramelli, R; Rancoita, P G; Ranieri, R; Raspereza, A V; Razis, P A; Ren, D; Rescigno, M; Reucroft, S; Riemann, S; Riles, K; Roe, B P; Romero, L; Rosca, A; Rosier-Lees, S; Roth, S; Rosenbleck, C; Roux, B; Rubio, J A; Ruggiero, G; Rykaczewski, H; Sakharov, A; Saremi, S; Sarkar, S; Salicio, J; Sánchez, E; Sanders, M P; Schäfer, C; Shchegelskii, V; Schopper, Herwig Franz; Schotanus, D J; Sciacca, C; Servoli, L; Shevchenko, S; Shivarov, N; Shoutko, V; Shumilov, E; Shvorob, A V; Son, D; Souga, C; Spillantini, P; Steuer, M; Stickland, D P; Stoyanov, B; Strässner, A; Sudhakar, K; Sultanov, G G; Sun, L Z; Sushkov, S; Suter, H; Swain, J D; Szillási, Z; Tang, X W; Tarjan, P; Tauscher, Ludwig; Taylor, L; Tellili, B; Teyssier, D; Timmermans, C; Ting, Samuel C C; Ting, S M; Tonwar, S C; Tóth, J; Tully, C; Tung, K L; Ulbricht, J; Valente, E; Van de Walle, R T; Vásquez, R; Veszpremi, V; Vesztergombi, G; Vetlitskii, I; Vicinanza, D; Viertel, Gert M; Villa, S; Vivargent, M; Vlachos, S; Vodopyanov, I; Vogel, H; Vogt, H; Vorobev, I; Vorobyov, A A; Wadhwa, M; Wang, X L; Wang, Z M; Weber, M; Wienemann, P; Wilkens, H; Wynhoff, S; Xia, L; Xu, Z Z; Yamamoto, J; Yang, B Z; Yang, C G; Yang, H J; Yang, M; Yeh, S C; Zalite, A; Zalite, Yu; Zhang, Z P; Zhao, J; Zhu, G Y; Zhu, R Y; Zhuang, H L; Zichichi, A; Zimmermann, B; Zöller, M

    2003-01-01

    A Higgs particle produced in association with a Z boson and decaying into weak boson pairs is searched for in 336.4 1/pb of data collected by the L3 experiment at LEP at centre-of-mass energies from 200 to 209 GeV. Limits on the branching fraction of the Higgs boson decay into two weak bosons as a function of the Higgs mass are derived. These results are combined with the L3 search for a Higgs boson decaying to photon pairs. A Higgs produced with a Standard Model e+e- --> Zh cross section and decaying only into electroweak boson pairs is excluded at 95% CL for a mass below 107 GeV.

  18. Weak Gauge Boson Radiation in Parton Showers

    CERN Document Server

    Christiansen, Jesper Roy

    2014-01-01

    The emission of W and Z gauge boson is included in a traditional QCD + QED shower. The unitarity of the shower algorithm links the real radiation of the weak gauge bosons to the negative weak virtual corrections. The shower evolution process leads to a competition between QCD, QED and weak radiation, and allows for W and Z boson production inside jets. Various effects on LHC physics are studied, both at low and high transverse momenta, and effects at higher-energy hadron colliders are outlined.

  19. Mapping the genuine bosonic quartic couplings

    CERN Document Server

    Eboli, O J P

    2016-01-01

    The larger center-of-mass energy of the Large Hadron Collider Run 2 opens up the possibility of a more detailed study of the quartic vertices of the electroweak gauge bosons. Our goal in this work is to classify all operators possessing quartic interactions among the electroweak gauge bosons that do not exhibit triple gauge-boson vertices associated to them. We obtain all relevant operators in the non-linear and linear realizations of the $SU(2)_L \\otimes U(1)_Y$ gauge symmetry.

  20. ATLAS measurements of vector boson production

    CERN Document Server

    Chavez Barajas, Carlos Alberto; The ATLAS collaboration

    2015-01-01

    ATLAS measurements of vector boson production, inclusive and with associated jets in pp collisions in LHC Run1 will be presented. The results are compared to NLO Monte Carlo simulations and to NNLO QCD predictions corrected for NLO EW effects. The production of jets in association with a W or a Z boson is an important process to study QCD in a multiscale environment in pp collisions at the LHC. The production of heavy flavour in association with a W or Z boson is sensitive to the parton density functions and to the modeling heavyquark flavour production mechanisms.

  1. Efimov Physics in small bosonic clusters

    CERN Document Server

    Gattobigio, M; Viviani, M

    2012-01-01

    We study small clusters of bosons, $A=2,3,4,5,6$, characterized by a resonant interaction. Firstly, we use a soft-gaussian interaction that reproduces the values of the dimer binding energy and the atom-atom scattering length obtained with LM2M2 potential, a widely used $^4$He-$^4$He interaction. We change the intensity of the potential to explore the clusters' spectra in different regions with large positive and large negative values of the two-body scattering length and we report the clusters' energies on Efimov plot, which makes the scale invariance explicit. Secondly, we repeat our calculation adding a repulsive three-body force to reproduce the trimer binding energy. In all the region explored, we have found that these systems present two states, one deep and one shallow close to the $A-1$ threshold, and scale invariance has been investigated for these states. The calculations are performed by means of Hyperspherical Harmonics basis set.

  2. Direct search for Higgs boson in LHCb

    CERN Document Server

    Currat, C

    2001-01-01

    The LHCb detector is a forward one-arm spectrometer to precision measurements of CP violation in the B-meson systems. The motivation of the present work is to assess the potential of LHCb to observe a Standard Model (SM) Higgs signal. The recent results obtained at LEP give a hint of a SM Higgs boson with a mass mH = 115.0 +1.3 –0.9 GeV/c2 with a statistical significance of 2.9 standard deviations. Because of the high longitudinal boost encountered by the products in the pp collisions at LHC, a significant fraction (~30%) of light Higgs (mH = 115 GeV/c2) are produced in the LHCb acceptance 1.8 < h < 4.9. These facts potentially place LHCb in the race for the observation of the SM Higgs. Given a relatively low running luminosity of 2 x 1032 cm-2s-1- compared to the nominal 1034 cm-2s-1 at LHC and a limited geometrical acceptance, we have shown that the channels accessible to LHCb are H + W± Z0 b`b + l± X for Higgs masses in the range 100-130 GeV/c2. This work pioneered a setup for the pro...

  3. Leptogenesis and neutral gauge bosons

    CERN Document Server

    Heeck, Julian

    2016-01-01

    We consider low-scale leptogenesis via right-handed neutrinos $N$ coupled to a $Z'$ boson, with gauged $U(1)_{B-L}$ as a simple realization. Keeping the neutrinos sufficiently out of equilibrium puts strong bounds on the $Z'$ coupling strength and mass, our focus being on light $Z'$ and $N$, testable in the near future by SHiP, HPS, Belle II, and at the LHC. We show that leptogenesis could be robustly falsified in a large region of parameter space by the double observation of $Z'$ and $N$, e.g. in the channel $pp\\to Z' \\to NN$ with displaced $N$-decay vertex, and by several experiments searching for light $Z'$, according to the mass of $N$.

  4. Invisible axionlike dark matter from the electroweak bosonic seesaw mechanism

    Science.gov (United States)

    Ishida, Hiroyuki; Matsuzaki, Shinya; Yamaguchi, Yuya

    2016-11-01

    We explore a model based on the classically scale-invariant standard model (SM) with a strongly coupled vectorlike dynamics, which is called hypercolor (HC). The scale symmetry is dynamically broken by the vectorlike condensation at the TeV scale, so that the SM Higgs acquires the negative mass squared by the bosonic seesaw mechanism to realize the electroweak symmetry breaking. An elementary pseudoscalar S is introduced to give masses for the composite Nambu-Goldstone bosons (HC pions): The HC pion can be a good target to explore through a diphoton channel at the LHC. As a consequence of the bosonic seesaw, the fluctuating mode of S , which we call s , develops tiny couplings to the SM particles and is predicted to be very light. The s predominantly decays to a diphoton and can behave as invisible axionlike dark matter. The mass of the s dark matter is constrained by currently available cosmological and astrophysical limits to be 10-4 eV ≲ms≲1 eV . We find that a sufficient amount of relic abundance for the s dark matter can be accumulated via the coherent oscillation. The detection potential in microwave cavity experiments is also addressed.

  5. Di-boson production and SM SUSY Higgs searches at the Tevatron

    Energy Technology Data Exchange (ETDEWEB)

    Elvira, V.Daniel; /Fermilab

    2005-07-01

    The discovery of the Higgs boson would be a major success for the Standard Model (SM) and would provide further insights into the electroweak symmetry breaking mechanism. This report contains the latest results from the D0 and CDF Tevatron experiments on searches for the SM Higgs produced from gluon fusion with H {yields} WW, and in association with a W boson. It also includes searches for a supersymmetric Higgs in the b{bar b} and {tau}{sup +}{tau}{sup -} decay channels. The study of di-boson production at the Tevatron is important to understand backgrounds in high mass Higgs searches. It also provides a test of the SM through the measurement of the production cross section and the gauge boson self couplings. This paper includes measurements of the WW, W{gamma}, and WZ production cross sections, as well as limits on the anomalous couplings associated with the WW{gamma} and WWZ interactions. The results are based on sets of up to 320 pb{sup -1} of data collected by the D0 and CDF experiments at the {bar p}p Tevatron collider, running at a center-of-mass energy of 1.96 TeV.

  6. Search for the SM Higgs Boson in the Channel $WH \\to l\

    CERN Document Server

    Will, Jonas Zacharias

    One of the most important scientific challenges of ATLAS and CMS, multi-purpose de- tectors at CERN’s Large Hadron Collider (LHC), is the discovery or exclusion of the longly sought standard model Higgs boson predicted almost fifty years ago. In summer 2012, both ATLAS and CMS discovered a new particle. Its mass is determined to be 126 . 0 ± 0 . 4 (stat) ± 0 . 4 (sys) GeV (ATLAS) and 125 . 3 ± 0 . 4 (stat) ± 0 . 5 (sys) GeV (CMS) [ 1 , 2 ]. Its further properties are so far consistent with the predicted properties of a standard model Higgs boson within large uncertainties. Besides the Higgs search in the sensitive bosonic channels, H → γγ , H → ZZ , and H → WW , the fermionic channels H → ττ and H → b b contributed to the exclusion of a standard model Higgs boson below the observed excess and are essential for measuring the couplings of the new particle to fermions. In the analysis presented here, the associated Higgs production WH in the Higgs decay channel H → b b is studied on the co...

  7. Higgs Spin Determination and Unitarity of Vector-boson Scattering at the LHC

    CERN Document Server

    Frank, Jessica

    After the discovery of a new particle at the Large Hadron Collider (LHC), it is crucial to definitely verify or disprove whether this new 125 − 126 GeV resonance is the Higgs boson of the Standard Model (SM). Thus, its features, including its spin, have to be determined. In order to distinguish the two most likely spin hypotheses, spin-0 or spin-2, the phenomenology of light spin-2 resonances produced in different gluon-fusion and vectorboson-fusion processes at the LHC is studied. Starting from an effective model for the interaction of a spin-2 particle with SM gauge bosons, cross sections and differential distributions are calculated within the Monte Carlo program Vbfnlo. Whereas with specific model parameters, such a spin-2 resonance can mimic rates and transverse-momentum distributions of a SM Higgs boson in the main decay channels γγ, WW and ZZ, several distributions allow to separate spin-2 from spin-0, almost independently of model parameters. Since the SM Higgs boson ensures the unitarity of the S...

  8. Discriminating between Z'-boson effects and effects of anomalous gauge couplings in the double production of W ± bosons at a linear collider

    Science.gov (United States)

    Andreev, Vasili V.; Pankov, A. A.

    2013-06-01

    The potential of the International Linear electron-positron Collider (ILC) for seeking, in the annihilation production of W ±-boson pairs, signals induced by new neutral gauge bosons predicted by models belonging to various classes and featuring an extended gauge sector is studied. Limits that will be obtained at ILC for the parameters and masses of Z' bosons are compared with present-day and future data from the Large Hadron Collider (LHC). The possibility of discriminating between the effects of Z-Z' mixing and signals induced by anomalous gauge couplings (AGC) is demonstrated within theoretically motivated trilinear gauge models involving several free anomalous parameters. It is found that the sensitivity of ILC to the effects of Z-Z' mixing in the process e + e - → W + W - and its ability to discriminate between these two new-physics scenarios, Z' and AGC, become substantially higher upon employing polarized initial ( e + e -) and final ( W ±) states.

  9. Searching Heavier Higgs Boson via $H \\to hh \\to WW^*\\gamma\\gamma$ at LHC Run-2

    CERN Document Server

    Lü, Lan-Chun; Fang, Yaquan; He, Hong-Jian; Zhang, Huijun

    2015-01-01

    The LHC discovery of a light Higgs particle $h^0$ (125GeV) opens up new prospect for searching heavier Higgs boson(s) at the LHC Run-2, which will unambiguously point to new physics beyond the standard model (SM). We study the detection of a heavier neutral Higgs boson $H^0$ via di-Higgs production channel at the LHC (14TeV), $H^0 \\to h^0h^0 \\to WW^*\\gamma\\gamma$. This directly probes the $Hhh$ cubic Higgs interaction, which exists in most extensions of the SM Higgs sector. For the decay products of final states $WW^*$, we include both pure leptonic mode $WW^* \\to \\ell\\bar{\

  10. A Historical Profile of the Higgs Boson

    Energy Technology Data Exchange (ETDEWEB)

    Ellis, John; Gaillard, Mary K.; Nanopoulos, Dimitri V.

    2012-01-31

    The Higgs boson was postulated in 1964, and phenomenological studies of its possible production and decays started in the early 1970s, followed by studies of its possible productionin e{sup +} e{sup -}, {anti p}p and pp collisions, in particular. Until recently, the most sensitive searches for the Higgs boson were at LEP between 1989 and 2000, which have been complemented bysearches at the Fermilab Tevatron. The LHC has recently entered the hunt, excluding a Higgs boson over a large range of masses and revealing a tantalizing hint in the range 119 to125 GeV, and there are good prospects that the existence or otherwise of the Higgs boson will soon be established. One of the most attractive possibilities is that the Higgs bosonis accompanied by supersymmetry, though composite options have yet to be excluded. This article reviews some of the key historical developments in Higgs physics over the past half-century.

  11. Majorization preservation of Gaussian bosonic channels

    Science.gov (United States)

    Jabbour, Michael G.; García-Patrón, Raúl; Cerf, Nicolas J.

    2016-07-01

    It is shown that phase-insensitive Gaussian bosonic channels are majorization-preserving over the set of passive states of the harmonic oscillator. This means that comparable passive states under majorization are transformed into equally comparable passive states by any phase-insensitive Gaussian bosonic channel. Our proof relies on a new preorder relation called Fock-majorization, which coincides with regular majorization for passive states but also induces another order relation in terms of mean boson number, thereby connecting the concepts of energy and disorder of a quantum state. The consequences of majorization preservation are discussed in the context of the broadcast communication capacity of Gaussian bosonic channels. Because most of our results are independent of the specific nature of the system under investigation, they could be generalized to other quantum systems and Hamiltonians, providing a new tool that may prove useful in quantum information theory and especially quantum thermodynamics.

  12. Higgs Boson search at the CMS experiment

    Directory of Open Access Journals (Sweden)

    Choudhury Somnath

    2014-04-01

    Full Text Available The results of the search for the Standard Model (SM Higgs Boson with the CMS detector in proton-proton collisions at the LHC at 7 TeV center-of-mass energy are reported. A large number of the Higgs Boson decay channels in the mass range from 110 GeV to 600 GeV are considered, and combined upper limits on the production cross section as a function of the Higgs Boson mass are derived. The SM Higgs is excluded at 95% confidence level in the mass range between 127.5 GeV and 600 GeV. In addition, searches for Higgs Bosons in scenarios Beyond the Standard Model (BSM lead to improved constraints on the Higgs sector of BSM theories such as supersymmetry.

  13. Boson--Fermion hybrid representation formulation, I

    Energy Technology Data Exchange (ETDEWEB)

    Wu, C.; Feng, D.H.

    1981-08-01

    A boson--fermion hybrid representation is presented. In this framework, a fermion system is described concurrently by the bosonic and the fermonic degrees of freedom. A fermion pair in this representation can be treated as a boson without violating the Pauli principle. Furthermore the ''bosonic interactions'' are shown to originate from the exchange processes of the fermions and can be calculated from the original fermion interactions. Both the formulation of the BFH representations for the even and odd nuclear systems are given. We find that the basic equation of the nuclear field theory (NFT) is just the usual Schroedinger equation in such a representation with the empirical NFT diagrammatic rules emerging naturally. This theory was numerically checked in the case of four nucleons moving in a single-j shell and the exactness of the theory was established.

  14. Supersymmetry search via gauge boson fusion

    Indian Academy of Sciences (India)

    Anindya Datta

    2003-02-01

    We propose a novel method for the search of supersymmetry, especially for the electroweak gauginos at the large hadron collider (LHC). Gauge boson fusion technique was shown to be useful for heavy and intermediate mass Higgs bosons. In this article, we have shown that this method can also be applied to find the signals of EW gauginos in supersymmetric theories where the canonical search strategies for these particles fail.

  15. Evolution of boson-fermion stars

    Science.gov (United States)

    Valdez-Alvarado, Susana; Palenzuela, Carlos; Alic, Daniela; Ureña-López, L. Arturo; Becerril, Ricardo

    2012-08-01

    The boson-fermion stars can be modeled with a complex scalar field coupled minimally to a perfect fluid (i.e., without viscosity and non-dissipative). We present a study of these solutions and their dynamical evolution by solving numerically the Einstein-Klein-Gordon-Hydrodynamic (EKGHD) system. It is shown that stable configurations exist, but stability of general configurations depends finely upon the number of bosons and fermions.

  16. Higgs boson couplings and properties with CMS

    CERN Document Server

    Finco, Linda

    2014-01-01

    Many different production and decay modes of the 126 GeV mass Higgs boson have been studied by the CMS collaboration at the LHC collider. The analysis is based on pp collision data col- lected at center-of-mass energies of 7 and 8 TeV corresponding to integrated luminosities of 5/fb and 20/fb respectively. The measurement of the Higgs boson couplings and of the study of its properties are presented.

  17. Bosonic Dynamical Mean-Field Theory

    Science.gov (United States)

    Snoek, Michiel; Hofstetter, Walter

    2013-02-01

    We derive the bosonic dynamical mean-field equations for bosonic atoms in optical lattices with arbitrary lattice geometry. The equations are presented as a systematic expansion in 1/z, z being the number of lattice neighbours. Hence the theory is applicable in sufficiently high-dimensional lattices. We apply the method to a two-component mixture, for which a rich phase diagram with spin order is revealed.

  18. Conformal gravity and the bosonic string

    Energy Technology Data Exchange (ETDEWEB)

    Julve, J.; Tiemblo, A.; Tresguerres, R.

    1987-09-01

    We show that the Callan et al. effective equations of motion for the bosonic closed string in a non-trivial background may not be derived only from the bosonic part of the N=1 supergravity action of Manton and Chapline, but also from just a general conformally invariant theory of gravity. In our scheme the invariance under gauge transformations of the antisymmetric tensor field turns out to be a consequence of the metricity condition.

  19. Deformed Bosons: Combinatorics of Normal Ordering

    CERN Document Server

    Blasiak, P; Penson, K A; Solomon, A I

    2004-01-01

    We solve the normal ordering problem for (A* A)^n where A* (resp. A) are one mode deformed bosonic creation (resp. annihilation) operators satisfying [A,A*]=[N+1]-[N]. The solution generalizes results known for canonical and q-bosons. It involves combinatorial polynomials in the number operator N for which the generating functions and explicit expressions are found. Simple deformations provide examples of the method.

  20. Diffractive Production of the Higgs Boson

    CERN Document Server

    Peschanski, R

    2003-01-01

    Diffractive production of the Higgs boson at hadron colliders is discussed in the light of the observed rate of hard diffractive dijet events at the Tevatron. The Higgs predictions of models successful for dijets are compared. LHC seems promising for a diffractive light Higgs boson and its mass determination. Hard diffractive dijets, diphotons and dileptons at the Tevatron (Run II) will be necessary to remove the remaining large uncertainties on cross-sections and signals.

  1. Electroweak Precision Data and New Gauge Bosons

    CERN Document Server

    Erler, Jens

    2009-01-01

    I review constraints on the Standard Model (SM) Higgs boson from high energy electroweak (EW) precision data. The same data set also strongly limits various mixing effects of hypothetical extra neutral gauge bosons (Z') with the ordinary Z. I also discuss low energy precision measurements which are sensitive to other aspects of Z' physics, such as the direct exchange amplitude and the flavor or CP violating sectors.

  2. Di-boson production at the Tevatron

    Energy Technology Data Exchange (ETDEWEB)

    De Lentdecker, Gilles; /Rochester U.

    2005-05-01

    The authors present some precision measurements on electroweak physics performed at the Tevatron collider at Fermilab. Namely they report on the boson-pair production cross sections and on triple gauge boson couplings using proton anti-proton collisions collected by the CDF and D0 experiments at the center-of-mass energy of 1.96 TeV. The data correspond to an integrated luminosity of up to 324 pb{sup -1}.

  3. Dynamical Study of 3D Boson Stars

    Science.gov (United States)

    Choi, Dae-Il; Choptuik, M. W.

    1998-10-01

    We study the dynamical evolution of ``boson stars'' in 3D numerical relativity. Boson stars are equilibrium states of a self-gravitating, complex Klein-Gordon field: a resurgence of interest in scalar fields in the context of astroparticle physics and quantum cosmology has prompted investigation of their dynamics, particularly since they are possible dark matter candidates. In addition, even though any direct physical relevance has yet to be demonstrated, boson star systems provide excellent numerical laboratories in which to study strong gravitational fields. Specifically, the boson star model provides an ideal vehicle with which to implement and evaluate (1) various coordinate conditions in the context of the ADM formalism, and (2) multi-dimensional adaptive mesh refinement techniques which appear crucial for many problems in 3D numerical relativity. We first consider boson stars in the Newtonian regime, where the (numerical) stability of single stars is shown and the interaction of multiple-star-systems is simulated. We also discuss issues which hamper progress towards a stable evolution of general relativistic boson stars, and then show some preliminary results for the general relativistic case.

  4. Neutral Supersymmetric Higgs Boson Searches

    Energy Technology Data Exchange (ETDEWEB)

    Robinson, Stephen Luke [Imperial College, London (United Kingdom)

    2008-07-01

    In some Supersymmetric extensions of the Standard Model, including the Minimal Supersymmetric Standard Model (MSSM), the coupling of Higgs bosons to b-quarks is enhanced. This enhancement makes the associated production of the Higgs with b-quarks an interesting search channel for the Higgs and Supersymmetry at D0. The identification of b-quarks, both online and offline, is essential to this search effort. This thesis describes the author's involvement in the development of both types of b-tagging and in the application of these techniques to the MSSM Higgs search. Work was carried out on the Level-3 trigger b-tagging algorithms. The impact parameter (IP) b-tagger was retuned and the effects of increased instantaneous luminosity on the tagger were studied. An extension of the IP-tagger to use the z-tracking information was developed. A new b-tagger using secondary vertices was developed and commissioned. A tool was developed to allow the use of large multi-run samples for trigger studies involving b-quarks. Offline, a neural network (NN) b-tagger was trained combining the existing offline lifetime based b-tagging tools. The efficiency and fake rate of the NN b-tagger were measured in data and MC. This b-tagger was internally reviewed and certified by the Collaboration and now provides the official b-tagging for all analyses using the Run IIa dataset at D0. A search was performed for neutral MSSM Higgs bosons decaying to a b{bar b} pair and produced in association with one or more b-quarks. Limits are set on the cross-section times the branching ratio for such a process. The limits were interpreted in various MSSM scenarios. This analysis uses the NN b-tagger and was the first to use this tool. The analysis also relies on triggers using the Level-3 IP b-tagging tool described previously. A likelihood discriminant was used to improve the analysis and a neural network was developed to cross-check this technique. The result of the analysis has been submitted to PRL

  5. Vector boson scattering, triple gauge-boson production and limits on anomalous quartic gauge-boson couplings with the ATLAS detector

    CERN Document Server

    Wang, Hulin; The ATLAS collaboration

    2016-01-01

    The production of vector boson scattering and triple gauge bosons are studied using $pp$ collisions at $\\sqrt{s}=8$ TeV with the ATLAS detector at the Large Hadron Collider. The vector boson scattering processes of $W^{\\pm}W^{\\pm}(\\rightarrow \\ell^{\\pm}\

  6. Computational methods in drug discovery

    Directory of Open Access Journals (Sweden)

    Sumudu P. Leelananda

    2016-12-01

    Full Text Available The process for drug discovery and development is challenging, time consuming and expensive. Computer-aided drug discovery (CADD tools can act as a virtual shortcut, assisting in the expedition of this long process and potentially reducing the cost of research and development. Today CADD has become an effective and indispensable tool in therapeutic development. The human genome project has made available a substantial amount of sequence data that can be used in various drug discovery projects. Additionally, increasing knowledge of biological structures, as well as increasing computer power have made it possible to use computational methods effectively in various phases of the drug discovery and development pipeline. The importance of in silico tools is greater than ever before and has advanced pharmaceutical research. Here we present an overview of computational methods used in different facets of drug discovery and highlight some of the recent successes. In this review, both structure-based and ligand-based drug discovery methods are discussed. Advances in virtual high-throughput screening, protein structure prediction methods, protein–ligand docking, pharmacophore modeling and QSAR techniques are reviewed.

  7. Search for the Higgs-Boson with the CDF experiment at Tevatron

    Energy Technology Data Exchange (ETDEWEB)

    Hennecke, Martin [Univ. of Karlsruhe (Germany)

    2005-06-10

    A search for a low-mass SM Higgs-Boson in the channel WH → lvb$\\bar{b}$ has been performed using neural networks. The data were taken by the CDF experiment at the p-$\\bar{p}$ collider Tevatron from 2000-2003, corresponding to in integrated luminosity of Lint = 162 pb-1 at a CMS-energy of √s = 1.96 TeV. 95% confidence level upper limits are set on σ × BR, the product of the production cross section times the Branching ratio, as a function of the Higgs boson mass. Cross sections above 8 pb are excluded for six different Higgs masses between 110 GeV/c2 and 150 GeV/c2. The required integrated luminosities for a 95% C.L. exclusion, 3σ evidence and 5σ discovery are calculated.

  8. A 125 GeV composite Higgs boson versus flavour and electroweak precision tests

    CERN Document Server

    Barbieri, Riccardo; Sala, Filippo; Straub, David M; Tesi, Andrea

    2012-01-01

    A composite Higgs boson of 125 GeV mass, only mildly fine-tuned, requires top partners with a semi-perturbative coupling and a mass not greater than about a TeV. We analyze the strong constraints on such picture arising from flavour and electroweak precision tests in models of partial compositeness. We consider different representations for the composite fermions and compare the case of an anarchic flavour structure to models with a U(3)^3 and U(2)^3 flavour symmetry. Although non trivially, some models emerge that look capable of accommodating a 125 GeV Higgs boson with top partners in an interesting mass range for discovery at the LHC as well as associated flavour signals.

  9. Looking for a hidden sector in exotic Higgs boson decays with the ATLAS experiment

    Directory of Open Access Journals (Sweden)

    Andrea Coccaro

    2015-12-01

    Full Text Available The nature of dark matter (DM is one of the most intriguing questions in particle physics. DM can be postulated to be part of a hidden sector whose interactions with the visible matter are not completely decoupled. The discovery of a fundamental scalar particle compatible with the Higgs boson predicted by the Standard Model paves the way for looking for DM with novel methods. An overview of the searches looking for a hidden sector in exotic Higgs decays and for invisible decays of the Higgs boson within the ATLAS experiment is presented. Prospects for searches with Large Hadron Collider data at a center-of-mass energy of 13 TeV are summarized.

  10. Search for the Standard Model Higgs Boson in associated production with w boson at the Tevatron

    Energy Technology Data Exchange (ETDEWEB)

    Chun, Xu [Univ. of Michigan, Ann Arbor, MI (United States)

    2009-11-01

    A search for the Standard Model Higgs boson in proton-antiproton collisions with center-of-mass energy 1.96 TeV at the Tevatron is presented in this dissertation. The process of interest is the associated production of W boson and Higgs boson, with the W boson decaying leptonically and the Higgs boson decaying into a pair of bottom quarks. The dataset in the analysis is accumulated by the D0 detector from April 2002 to April 2008 and corresponding to an integrated luminosity of 2.7 fb-1. The events are reconstructed and selected following the criteria of an isolated lepton, missing transverse energy and two jets. The D0 Neural Network b-jet identification algorithm is further used to discriminate b jets from light jets. A multivariate analysis combining Matrix Element and Neural Network methods is explored to improve the Higgs boson signal significance. No evidence of the Higgs boson is observed in this analysis. In consequence, an observed (expected) limit on the ratio of σ (p$\\bar{p}$ → WH) x Br (H → b$\\bar{b}$) to the Standard Model prediction is set to be 6.7 (6.4) at 95% C.L. for the Higgs boson with a mass of 115 GeV.

  11. Diphoton lineshape of the BEH boson using the ATLAS detector at the LHC calibration, mass, width and interferences

    CERN Document Server

    AUTHOR|(SzGeCERN)709331

    Since the data collected during the first run of the LHC by the ATLAS and CMS collaborations allowed for the discovery of the BEH boson, a huge effort has been done toward the detailed studies of its properties. This thesis is particularly oriented toward the understanding of the BEH boson lineshape in its diphoton decay channel, using the data collected by the ATLAS detector in 2011 and 2012. The electromagnetic calibration of the ATLAS detector is described in details, and the precise measurement of the BEH boson mass it allowed for, at $m_h = 125.98 \\pm 0.50$ GeV, is summarized. A first upper limit on the BEH boson decay width, that gave a limit at $\\Gamma_h < 5.3$ GeV at 95% C.L., is presented in details). The last part of this thesis presents a study of quantum interferences between signal and background processes in the $gg \\rightarrow \\gamma\\gamma$ channel, which are expected to distord the diphoton lineshape and create a shift of the measured BEH boson mass, that is estimated to be of 35 MeV, which...

  12. Probing CP properties of the discovered bosonic resonance with Higgs signal rates from Tevatron and LHC data

    Energy Technology Data Exchange (ETDEWEB)

    Klingl, Tobias; Bechtle, Philip; Desch, Klaus [Universitaet Bonn (Germany); Stefaniak, Tim [University of California, Santa Cruz (United States)

    2016-07-01

    In July 2012, the ATLAS and CMS collaborations reported the discovery of a single, narrow bosonic resonance φ with mass of 125 GeV. Although a pure CP-odd state can be excluded by the current data, it is still possible that the CP properties of this resonance deviate from the expectations for a pure CP-even Standard Model (SM) Higgs boson. In general it can be an admixture of a CP-even Higgs-like scalar h and a CP-odd pseudoscalar A described by the general parametrization φ = cosα h + sinα A. We investigate the scope of possible discrepancies between the CP properties and the couplings of the discovered resonance and the properties of a SM Higgs boson. To this end, we consider a Higgs coupling scale factor benchmark scenario with scalar and pseudoscalar scale factors for the Higgs couplings to fermions and one scalar scale factor for the SU(2) gauge bosons. The latter coupling is assumed to be ≤1, as predicted in many models such as SUSY or the 2HDM. Additionally, we allow for non-SM Higgs boson decays into invisible final states. We perform χ{sup 2} fits to the available data from the Tevatron and LHC experiments using the Computer Code HiggsSignals, which takes into account signal efficiencies and major correlations of experimental and theoretical uncertainties. We obtain constraints on the mixing angle α and the scalar and pseudoscalar couplings of the field φ.

  13. Top quark, W-boson and light Higgs

    Energy Technology Data Exchange (ETDEWEB)

    Parke, S.

    1997-10-01

    The top quark, the W-boson and the Higg boson form an interesting triptych of elementary particles. In the Standard Model knowing the mass of two of these particles, usually the top quark and W-boson, we can predict the mass of the third, the Higgs boson. Therefore in this proceedings I will primarily cover the following topics, top quark physics, W-boson mass and the light Higgs boson at the proton-antiproton collider at Fermilab, the Tevatron. Other hadron collider topics to be cover in this conference include B-physics, QCD, Electroweak Physics, and Supersymmetry.

  14. Model-Independent Description and Large Hadron Collider Implications of Suppressed Two-Photon Decay of a Light Higgs Boson

    CERN Document Server

    Phalen, D; Wells, J D; Phalen, Daniel; Thomas, Brooks; Wells, James D.

    2006-01-01

    For a Standard Model Higgs boson with mass between 115 GeV and 150 GeV, the two-photon decay mode is important for discovery at the Large Hadron Collider (LHC). We describe the interactions of a light Higgs boson in a more model-independent fashion, and consider the parameter space where there is no two-photon decay mode. We argue from generalities that analysis of the $t\\bar t h$ discovery mode outside its normally thought of range of applicability is especially needed under these circumstances. We demonstrate the general conclusion with a specific example of parameters of a type I two-Higgs doublet theory, motivated by ideas in strongly coupled model building. We then specify a complete set of branching fractions and discuss the implications for the LHC.

  15. Bosonic self-energy functional theory

    Science.gov (United States)

    Hügel, Dario; Werner, Philipp; Pollet, Lode; Strand, Hugo U. R.

    2016-11-01

    We derive the self-energy functional theory for bosonic lattice systems with broken U(1) symmetry by parametrizing the bosonic Baym-Kadanoff effective action in terms of one- and two-point self-energies. The formalism goes beyond other approximate methods such as the pseudoparticle variational cluster approximation, the cluster composite boson mapping, and the Bogoliubov+U theory. It simplifies to bosonic dynamical-mean-field theory when constraining to local fields, whereas when neglecting kinetic contributions of noncondensed bosons, it reduces to the static mean-field approximation. To benchmark the theory, we study the Bose-Hubbard model on the two- and three-dimensional cubic lattice, comparing with exact results from path integral quantum Monte Carlo. We also study the frustrated square lattice with next-nearest-neighbor hopping, which is beyond the reach of Monte Carlo simulations. A reference system comprising a single bosonic state, corresponding to three variational parameters, is sufficient to quantitatively describe phase boundaries and thermodynamical observables, while qualitatively capturing the spectral functions, as well as the enhancement of kinetic fluctuations in the frustrated case. On the basis of these findings, we propose self-energy functional theory as the omnibus framework for treating bosonic lattice models, in particular, in cases where path integral quantum Monte Carlo methods suffer from severe sign problems (e.g., in the presence of nontrivial gauge fields or frustration). Self-energy functional theory enables the construction of diagrammatically sound approximations that are quantitatively precise and controlled in the number of optimization parameters but nevertheless remain computable by modest means.

  16. Muon g-2 Anomaly and Dark Leptonic Gauge Boson

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Hye-Sung [W& M

    2014-11-01

    One of the major motivations to search for a dark gauge boson of MeV-GeV scale is the long-standing muon g-2 anomaly. Because of active searches such as fixed target experiments and rare meson decays, the muon g-2 favored parameter region has been rapidly reduced. With the most recent data, it is practically excluded now in the popular dark photon model. We overview the issue and investigate a potentially alternative model based on the gauged lepton number or U(1)_L, which is under different experimental constraints.

  17. Critical Points in Nuclei and Interacting Boson Model Intrinsic States

    CERN Document Server

    Ginocchio, J N; Ginocchio, Joseph N.

    2003-01-01

    We consider properties of critical points in the interacting boson model, corresponding to flat-bottomed potentials as encountered in a second-order phase transition between spherical and deformed $\\gamma$-unstable nuclei. We show that intrinsic states with an effective $\\beta$-deformation reproduce the dynamics of the underlying non-rigid shapes. The effective deformation can be determined from the the global minimum of the energy surface after projection onto the appropriate symmetry. States of fixed $N$ and good O(5) symmetry projected from these intrinsic states provide good analytic estimates to the exact eigenstates, energies and quadrupole transition rates at the critical point.

  18. Vector Boson Scattering, Triple Gauge-Boson Production, and Limits on Anomalous Quartic Gauge-Boson Couplings with the ATLAS Detector

    CERN Document Server

    Wang, Hulin; The ATLAS collaboration

    2016-01-01

    Vector-boson scattering processes provide a unique way to probe the mechanism of electroweak symmetry breaking. Similar physics can be probed by studying the production of three gauge bosons. The results can also be used for a model-independent search for new physics at the TeV scale via anomalous quartic gauge couplings. The ATLAS collaboration has studied vector boson scattering in final states with two gauge bosons and two forward jets in 20.3 /fb of 8TeV proton-proton collision data, in particular two same-sign W bosons, a WZ boson pair, and a W or Z boson in association with an isolated photon. The studies are complemented by a search for anomalous vector boson production of WW+WZ pairs in their semileptonic decays to lnujj in association with two forward jets. The collaboration has used this data set as well to study the production of three gauge bosons. A search was carried out for the production of three W bosons. The cross sections for the production of a W or Z boson in association with two isolated...

  19. Our dear boson – and so what?

    CERN Multimedia

    Antonella Del Rosso

    2012-01-01

    A long-sought particle finally found. On Wednesday 4 July, enthusiasm spread from CERN to the worldwide media. But a question legitimately arises: why is this particle attracting so much interest? In other words, how is it different from all the others? (And, by the way, what is a boson?).   CERN, 4 July 2012: a long-sought particle finally found. Strictly speaking, we cannot even call it the “Higgs” boson yet. Only after careful checking of its properties will physicists be able to say if the new boson corresponds to the particle that theorists predicted in 1964. However, the experimental data we have so far already tells us, unambiguously, that this new particle is different from all the other elementary particles we know. “Every particle is either a boson or a fermion,” explains John Ellis, former CERN theorist and currently professor at King's College in London. “All known particles spin like small tops, with the known bosons tha...

  20. ATLAS measurements of vector boson production

    CERN Document Server

    Debenedetti, Chiara; The ATLAS collaboration

    2016-01-01

    Vector boson production in pp collisions at 7, 8 and 13 TeV has been extensively studied by ATLAS. Recent results include the precision measurements of the transverse momentum of the Z/gamma* boson production, sensitive to soft resummation effects, hard jet emissions and electroweak corrections. A precise measurement of the angular coefficients of the Z­boson production tests the underlying QCD dynamics of the Drell­Yan process. A first measurement of the inclusive W and Z cross section at a cms energy of 13TeV has been derived. The Production of jets in association with a vector boson is an important process to study QCD in a multi­scale environment. Cross sections, differential in several kinematics variables, have been measured with the ATLAS detector and compared to state­of­the­art QCD calculations and Monte Carlo simulations. First measurements of vector boson + jets production have been performed at cms energies of 13TeV. An overview of these results is given.

  1. Ratio method of measuring W boson mass

    Energy Technology Data Exchange (ETDEWEB)

    Guo, Feng [Stony Brook Univ., NY (United States)

    2010-08-01

    This dissertation describes an alternative method of measuring the W boson mass in DØ experiment. Instead of extracting MW from the fitting of W → ev fast Monte Carlo simulations to W → ev data as in the standard method, we make the direct fit of transverse mass between W → ev data and Z → ee data. One of the two electrons from Z boson is treated as a neutrino in the calculation of transverse mass. In ratio method, the best fitted scale factor corresponds to the ratio of W and Z boson mass (MW/MZ). Given the precisely measured Z boson mass, W mass is directly fitted from W → ev and Z → ee data. This dissertation demonstrates that ratio method is a plausible method of measuring the W boson mass. With the 1 fb-1 DØ Run IIa dataset, ratio method gives MW = 80435 ± 43(stat) ± 26(sys) MeV.

  2. Vector boson pair production at hadron colliders

    CERN Document Server

    Adamson, K L

    2002-01-01

    We calculate the contribution of gluon-gluon induced processes to vector boson pair production at hadron colliders, specifically the production of WZ, W gamma and Z gamma pairs. We calculate the tree level processes gg -> WZqq-bqr, gg -> W gamma qq-bar and gg -> Z gamma qq-bar, and the one loop process gg -> Z gamma. We use the helicity method and include the decay of the W and Z bosons into leptons in the narrow width approximation. We include anomalous triple gauge couplings in all of our vector boson pair production calculations. In order to integrate over the qq-bar final state phase space we use an extended version of the subtraction method to NNLO and cancel collinear singularities explicitly. The general subtraction terms that are obtained apply to all vector boson pair production processes. Due to the large gluon density at low x, the gluon induced terms of vector boson pair production are expected to be the dominant NNLO QCD correction, relevant at LHC energies. However, we show that due to a cancell...

  3. A sensitivity study for Higgs boson production in Vector Boson Fusion in the H {yields} {tau}{tau} {yields} lh+3{nu} final state with ATLAS

    Energy Technology Data Exchange (ETDEWEB)

    Moeser, Nicolas

    2011-11-15

    For a hypothetical Higgs boson mass between 114.4 GeV and about 135 GeV the production by Vector Boson Fusion and the decay H {yields} {tau}{tau} {yields} lh + 3{nu} is one of the most promising discovery channels at the LHC. In this thesis, a study of the expected sensitivity of the ATLAS detector for this channel at a centre-of-mass energy of 14 TeV is presented. For the first time, this study includes a full treatment of additional proton-proton interactions, so-called pile-up. The presence of pile-up significantly affects the signal selection efficiency and leads to a deterioration of the reconstructed Higgs boson mass, which is used as a discriminating observable. Two methods have been developed to estimate the dominant background processes from data. By replacing the muons in Z {yields} {mu}{mu} events with simulated {tau} lepton decays, Z {yields} {tau}{tau} events can be modelled with high precision. The non-resonant background, t anti t production and W+jets, is estimated by selecting events where lepton and hadronic {tau} decay have the same electric charge. Assuming a dataset corresponding to an integrated luminosity of 30 fb{sup -1}, an expected signal significance between 3.0 {sigma} and 4.4{sigma} is obtained for a Higgs boson mass between 115 GeV and 135 GeV. The expected significance decreases to 1.6-2.0{sigma} in the presence of pile-up. (orig.)

  4. Orbital optical lattices with bosons

    Science.gov (United States)

    Kock, T.; Hippler, C.; Ewerbeck, A.; Hemmerich, A.

    2016-02-01

    This article provides a synopsis of our recent experimental work exploring Bose-Einstein condensation in metastable higher Bloch bands of optical lattices. Bipartite lattice geometries have allowed us to implement appropriate band structures, which meet three basic requirements: the existence of metastable excited states sufficiently protected from collisional band relaxation, a mechanism to excite the atoms initially prepared in the lowest band with moderate entropy increase, and the possibility of cross-dimensional tunneling dynamics, necessary to establish coherence along all lattice axes. A variety of bands can be selectively populated and a subsequent thermalization process leads to the formation of a condensate in the lowest energy state of the chosen band. As examples the 2nd, 4th and 7th bands in a bipartite square lattice are discussed. The geometry of the 2nd and 7th bands can be tuned such that two inequivalent energetically degenerate energy minima arise at the X ±-points at the edge of the 1st Brillouin zone. In this case even a small interaction energy is sufficient to lock the phase between the two condensation points such that a complex-valued chiral superfluid order parameter can emerge, which breaks time reversal symmetry. In the 4th band a condensate can be formed at the Γ-point in the center of the 1st Brillouin zone, which can be used to explore topologically protected band touching points. The new techniques to access orbital degrees of freedom in higher bands greatly extend the class of many-body scenarios that can be explored with bosons in optical lattices.

  5. Integrability and Quantum Phase Transitions in Interacting Boson Models

    CERN Document Server

    Dukelsky, J; García-Ramos, J E; Pittel, S

    2003-01-01

    The exact solution of the boson pairing hamiltonian given by Richardson in the sixties is used to study the phenomena of level crossings and quantum phase transitions in the integrable regions of the sd and sdg interacting boson models.

  6. Measurements of the Higgs boson properties with the ATLAS detector

    CERN Document Server

    Tomoto, M; The ATLAS collaboration

    2013-01-01

    Slide draft for the Crimea 2013 workshop. The subject of the talk will be measurements of the Higgs boson properties, including the spin, mass, signal strength, and couplings of a new boson discovered in 2012 at the ATLAS experiment.

  7. Energy spectrum and phase diagrams of two-sublattice hard-core boson model

    Directory of Open Access Journals (Sweden)

    I.V. Stasyuk

    2013-06-01

    Full Text Available The energy spectrum, spectral density and phase diagrams have been obtained for two-sublattice hard-core boson model in frames of random phase approximation approach. Reconstruction of boson spectrum at the change of temperature, chemical potential and energy difference between local positions in sublattices is studied. The phase diagrams illustrating the regions of existence of a normal phase which can be close to Mott-insulator (MI or charge-density (CDW phase diagrams as well as the phase with the Bose-Einstein condensate (SF phase are built.

  8. Competing bosonic condensates in optical lattice with a mixture of single and pair hoppings

    Science.gov (United States)

    Travin, V. M.; Kopeć, T. K.

    2017-01-01

    A system of ultra-cold atoms with single boson and pair tunneling of bosonic atoms is considered in an optical lattice at arbitrary temperature. A mean-field theory was applied to the extended Bose-Hubbard Hamiltonian describing the system in order to investigate the competition between superfluid and pair superfluid as a function of the chemical potential and the temperature. To this end we have applied a method based on the Laplace transform method for the efficient calculation of the statistical sum for the quantum Hamiltonian. These results may be of interest for experiments on cold atom systems in optical lattices.

  9. Search for a Higgs Boson Produced in Association with a W Boson at ATLAS

    CERN Document Server

    Ruckert, Benjamin

    The Large Hadron Collider at CERN is the most modern proton-proton collider and data taking will start in 2009, with a centre-of-mass energy of 7 TeV. The ATLAS detector, which is one of two multi-purpose detectors at the Large Hadron Collider, is able to detect a Standard Model Higgs boson if it exists. This is one of the main tasks of the ATLAS experiment. This thesis deals with a Standard Model Higgs boson produced in association with a W boson. The Monte Carlo study is based on physics events generated at the nominal centre-of-mass energy of the Large Hadron Collider of 14 TeV. Large parts of this analysis have been done using the global Grid infrastructure of the Large Hadron Collider experiments. A mass range of the Higgs boson of mH = 130 - 190 GeV has been taken into account. In this mass range, the Higgs boson dominantly decays into a pair of W bosons, leading to initially three W bosons: WH -> WWW. Two orthogonal analysis channels have been investigated in detailed studies of the background properti...

  10. Vector boson and charmonia measurements in $p$+Pb collisions with ATLAS

    CERN Document Server

    INSPIRE-00244603

    2016-01-01

    The production of electroweak bosons ($Z,\\gamma$ and $W$) and charmonia is sensitive to the initial-state geometry of heavy-ion collisions and to the parton distribution function with its potential nuclear modification. Since their leptonic decay products do not interact strongly, their kinematics are unmodified by the strongly interacting medium, which can be created in a heavy-ion collision. We report on the latest results of the ATLAS Collaboration on electroweak boson and charmonia production in $p$+Pb collisions at $\\sqrt{s_{\\rm NN}} = 5.02$ TeV. Production yields of $Z$ and $W$ bosons are presented as a function of (pseudo-)rapidity in different centrality bins. The forward-backward ratio of J/$\\psi$ is shown as a function of transverse momentum and center-of-mass rapidity.

  11. Spectral flow of trimer states of two heavy impurities and one light condensed boson

    Science.gov (United States)

    Zinner, Nikolaj T.

    2014-09-01

    The spectral flow of three-body (trimer) states consisting of two heavy (impurity) particles sitting in a condensate of light bosons is considered. Assuming that the condensate is weakly interacting and that an impurity and a boson have a resonant zero-range two-body interaction, we use the Born-Oppenheimer approximation to determine the effective three-body potential. We solve the resulting Schrödinger equation numerically and determine the trimer binding energies as a function of the coherence length of the light bosonic condensate particles. The binding energy is found to be suppressed by the presence of the condensate when the energy scale corresponding to the coherence length becomes of order the trimer binding energy in the absence of the condensate. We find that the Efimov scaling property is reflected in the critical values of the condensate coherence length at which the trimers are pushed into the continuum.

  12. Exit from accelerated regimes by symmetry breaking in a universe filled with fermionic and bosonic sources

    CERN Document Server

    Ribas, Marlos O; Devecchi, Fernando P; Kremer, Gilberto M

    2014-01-01

    In this work we investigate a universe filled with a fermionic field and a complex scalar field, exchanging energy through a Yukawa potential; the model encodes a symmetry breaking mechanism (on the bosonic sector). In a first case, when the mechanism is not included, the cosmological model furnishes a pure accelerated regime. In a second case, when including the symmetry breaking mechanism, we verify that the fermion and one of the bosons, of Higgs type, become massive, while the other boson is massless. Besides, the mechanism shows to be responsible for a transition from an accelerated to a decelerated regime, which certifies the importance, in cosmological terms, of its role. After symmetry breaking, the total pressure of the fields change its sign from negative to positive corresponding to the accelerated-decelerated transition. For large times the universe becomes a dust (pressureless) dominated Universe.

  13. Higgs boson mass in the Standard Model at two-loop order and beyond

    Energy Technology Data Exchange (ETDEWEB)

    Martin, Stephen P. [Northern Illinois U.; Robertson, David G. [Otterbein Coll.

    2014-10-23

    We calculate the mass of the Higgs boson in the standard model in terms of the underlying Lagrangian parameters at complete 2-loop order with leading 3-loop corrections. A computer program implementing the results is provided. The program also computes and minimizes the standard model effective potential in Landau gauge at 2-loop order with leading 3-loop corrections.

  14. Random walk with a boundary line as a free massive boson with a defect line

    CERN Document Server

    Valleriani, A

    1995-01-01

    We show that the problem of Random Walk with boundary attractive potential may be mapped onto the free massive bosonic Quantum Field Theory with a line of defect. This mapping permits to recover the statistical properties of the Random Walks by using boundary S--matrix and Form Factor techniques.

  15. Results on BSM Higgs boson searches at ATLAS

    CERN Document Server

    Giulini, Maddalena; The ATLAS collaboration

    2016-01-01

    Many beyond the SM theories (BSM) foresee a complex Higgs sector and hence additional Higgs bosons. These new scalar particles could appear as excesses in events containing two bosons or two fermions. Direct searches for BSM Higgs bosons in final states with tau leptons, heavy quarks or vector bosons have been performed by the ATLAS experiment at the LHC. Recent results of these searches are reviewed in this article.

  16. Quantum simulation with a boson sampling circuit

    Science.gov (United States)

    González Olivares, Diego; Peropadre, Borja; Aspuru-Guzik, Alán; García-Ripoll, Juan José

    2016-08-01

    In this work we study a system that consists of 2 M matter qubits that interact through a boson sampling circuit, i.e., an M -port interferometer, embedded in two different architectures. We prove that, under the conditions required to derive a master equation, the qubits evolve according to effective bipartite X Y spin Hamiltonians, with or without local and collective dissipation terms. This opens the door to the simulation of any bipartite spin or hard-core boson models and exploring dissipative phase transitions as the competition between coherent and incoherent exchange of excitations. We also show that in the purely dissipative regime this model has a large number of exact and approximate dark states, whose structure and decay rates can be estimated analytically. We finally argue that this system may be used for the adiabatic preparation of boson sampling states encoded in the matter qubits.

  17. Light gauge boson in rare $K$ decay

    CERN Document Server

    Chen, Chuan-Hung

    2016-01-01

    The inconsistent conclusions for a light gauge boson $X$ production in the $K^- \\to \\pi^- X$ exist in the literature. It is found that the process can be generated by the tree-level $W$-boson annihilation and loop-induced $s\\to dX$. We find that it strongly depends on the $SU(3)$ limit or the unique gauge coupling to the quarks, whether the $K^-\\to \\pi^- X$ decay, which is from the $W$-boson annihilation, is suppressed by $m^2_X \\epsilon_X \\cdot p_K$; however, no such suppression is found via the loop-induced $s\\to d X$. The constraints on the relevant couplings are studied.

  18. W Boson Polarisation at LEP2

    CERN Document Server

    Abbiendi, G; Åkesson, P F; Alexander, G; Allison, J; Amaral, P; Anagnostou, G; Anderson, K J; Arcelli, S; Asai, S; Axen, D A; Azuelos, Georges; Bailey, I; Barberio, E; Barillari, T; Barlow, R J; Batley, J Richard; Bechtle, P; Behnke, T; Bell, K W; Bell, P J; Bella, G; Bellerive, A; Benelli, G; Bethke, Siegfried; Biebel, O; Boeriu, O; Bock, P; Boutemeur, M; Braibant, S; Brigliadori, L; Brown, R M; Büsser, K; Burckhart, H J; Campana, S; Carnegie, R K; Carter, A A; Carter, J R; Chang, C Y; Charlton, D G; Ciocca, C; Couchman, J; Csilling, Akos; Cuffiani, M; Dado, S; de Roeck, A; De Wolf, E A; Desch, Klaus; Dienes, B; Donkers, M; Dubbert, J; Duchovni, E; Duckeck, G; Duerdoth, I P; Etzion, E; Fabbri, Franco Luigi; Feld, L; Ferrari, P; Fiedler, F; Fleck, I; Ford, M; Frey, A; Gagnon, P; Gary, J W; Gaycken, G; Geich-Gimbel, C; Giacomelli, G; Giacomelli, P; Giunta, M; Goldberg, J; Gross, E; Grunhaus, Jacob; Gruwé, M; Günther, P O; Sen-Gupta, A; Hajdu, C; Hamann, M; Hanson, G G; Harel, A; Hauschild, M; Hawkes, C M; Hawkings, R; Hemingway, Richard J; Herten, G; Heuer, R D; Hill, J C; Hoffman, K; Horváth, D; Igo-Kemenes, P; Ishii, K; Jeremie, H; Jovanovic, P; Junk, T R; Kanaya, N; Kanzaki, J; Karlen, Dean A; Kawagoe, K; Kawamoto, T; Keeler, Richard K; Kellogg, R G; Kennedy, B W; Klein, K; Klier, A; Kluth, S; Kobayashi, T; Kobel, M; Komamiya, S; Kramer, T; Krieger, P; Von Krogh, J; Krüger, K; Kühl, T; Kupper, M; Lafferty, G D; Landsman, Hagar Yaël; Lanske, D; Layter, J G; Lellouch, D; Letts, J; Levinson, L; Lillich, J; Lloyd, S L; Loebinger, F K; Lü, J; Ludwig, A; Ludwig, J; Mader, W; Marcellini, S; Martin, A J; Masetti, G; Mashimo, T; Mättig, P; McKenna, J A; McPherson, R A; Meijers, F; Menges, W; Merritt, F S; Mes, H; Michelini, Aldo; Mihara, S; Mikenberg, G; Miller, D J; Moed, S; Mohr, W; Mori, T; Mutter, A; Nagai, K; Nakamura, I; Nanjo, H; Neal, H A; Nisius, R; O'Neale, S W; Oh, A; Okpara, A N; Oreglia, M J; Orito, S; Pahl, C; Pásztor, G; Pater, J R; Pilcher, J E; Pinfold, J L; Plane, D E; Poli, B; Pooth, O; Przybycien, M B; Quadt, A; Rabbertz, K; Rembser, C; Renkel, P; Roney, J M; Rosati, S; Rozen, Y; Runge, K; Sachs, K; Saeki, T; Sarkisyan-Grinbaum, E; Schaile, A D; Schaile, O; Scharff-Hansen, P; Schieck, J; Schörner-Sadenius, T; Schröder, M; Schumacher, M; Scott, W G; Seuster, R; Shears, T G; Shen, B C; Sherwood, P; Skuja, A; Smith, A M; Sobie, R J; Söldner-Rembold, S; Spanó, F; Stahl, A; Strom, D; Ströhmer, R; Tarem, S; Tasevsky, M; Teuscher, R; Thomson, M A; Torrence, E; Toya, D; Tran, P; Trigger, I; Trócsányi, Z L; Tsur, E; Turner-Watson, M F; Ueda, I; Ujvári, B; Vollmer, C F; Vannerem, P; Vertesi, R; Verzocchi, M; Voss, H; Vossebeld, Joost Herman; Waller, D; Ward, C P; Ward, D R; Watkins, P M; Watson, A T; Watson, N K; Wells, P S; Wengler, T; Wermes, N; Wetterling, D; Wilson, G W; Wilson, J A; Wolf, G; Wyatt, T R; Yamashita, S; Zer-Zion, D; Zivkovic, L

    2004-01-01

    Elements of the spin density matrix for W bosons in e+e- -> W+W- -> qqln events are measured from data recorded by the OPAL detector at LEP. This information is used calculate polarised differential cross-sections and to search for CP-violating effects. Results are presented for W bosons produced in e+e- collisions with centre-of-mass energies between 183 GeV and 209 GeV. The average fraction of W bosons that are longitudinally polarised is found to be (23.9 +- 2.1 +- 1.1)% compared to a Standard Model prediction of (23.9 +- 0.1)%. All results are consistent with CP conservation.

  19. Efficient experimental validation of photonic boson sampling

    CERN Document Server

    Spagnolo, N; Bentivegna, M; Brod, D J; Crespi, A; Flamini, F; Giacomini, S; Milani, G; Ramponi, R; Mataloni, P; Osellame, R; Galvao, E F; Sciarrino, F

    2013-01-01

    A boson sampling device is a specialised quantum computer that solves a problem which is strongly believed to be computationally hard for classical computers. Recently a number of small-scale implementations have been reported, all based on multi-photon interference in multimode interferometers. In the hard-to-simulate regime, even validating the device's functioning may pose a problem. In a recent criticism of boson sampling experiments, Gogolin et al. argued that the output would be effectively indistinguishable from the trivial, uniform distribution. Here we report new boson sampling experiments on larger photonic chips, and analyse the data using a scalable statistical test recently proposed by Aaronson and Arkhipov. We show the test successfully validates small experimental data samples against the hypothesis that they are uniformly distributed. We also show how to discriminate data arising from either indistinguishable or distinguishable photons. Our results pave the way towards demonstrating the quantu...

  20. Bosonic-Seesaw Portal Dark Matter

    CERN Document Server

    Ishida, Hiroyuki; Yamaguchi, Yuya

    2016-01-01

    We propose a new type of Higgs-portal dark matter-production mechanism, called bosonic-seesaw portal scenario. Bosonic seesaw provides the dynamical origin of the electroweak symmetry breaking, triggered by mixing between the elementary Higgs and a composite Higgs generated by a new-color strong dynamics (hypercolor) which dynamically breaks the classical-scale invariance of the model. The composite hypercolor-baryonic matter can then be a dark matter candidate, which significantly couples to the standard-model Higgs via the bosonic seesaw, and can be produced from the thermal plasma below the decoupling temperature around the new strong coupling scale, to account for the observed relic abundance of the dark matter: the dark matter can closely be related to the mechanism of the electroweak symmetry breaking.

  1. The general boson normal ordering problem

    CERN Document Server

    Blasiak, P; Solomon, A I; Blasiak, Pawel; Penson, Karol A.; Solomon, Allan I.

    2003-01-01

    We solve the boson normal ordering problem for F[(a*)^r a^s], with r,s positive integers, where a* and a are boson creation and annihilation operators satisfying [a,a*]=1. That is, we provide exact and explicit expressions for the normal form wherein all a's are to the right. The solution involves integer sequences of numbers which are generalizations of the conventional Bell and Stirling numbers whose values they assume for r=s=1. A comprehensive theory of such generalized combinatorial numbers is given including closed-form expressions (extended Dobinski-type formulas)and generating functions. These last are special expectation values in boson coherent states.

  2. Boson Stars in AdS

    CERN Document Server

    Buchel, Alex; Lehner, Luis

    2013-01-01

    We construct boson stars in global Anti de Sitter (AdS) space and study their stability. Linear perturbation results suggest that the ground state along with the first three excited state boson stars are stable. We evolve some of these solutions and study their nonlinear stability in light of recent work \\cite{Bizon:2011gg} arguing that a weakly turbulent instability drives scalar perturbations of AdS to black hole formation. However evolutions suggest that boson stars are nonlinearly stable and immune to the instability for sufficiently small perturbation. Furthermore, these studies find other families of initial data which similarly avoid the instability for sufficiently weak parameters. Heuristically, we argue that initial data families with widely distributed mass-energy distort the spacetime sufficiently to oppose the coherent amplification favored by the instability. From the dual CFT perspective our findings suggest that there exist families of rather generic initial conditions in strongly coupled CFT ...

  3. Elementary Goldstone Higgs Boson and Dark Matter

    DEFF Research Database (Denmark)

    Alanne, Tommi; Gertov, Helene; Sannino, Francesco

    2015-01-01

    We investigate a perturbative extension of the Standard Model featuring elementary pseudo-Goldstone Higgs and dark matter particles. These are two of the five Goldstone bosons parametrising the SU(4)/Sp(4) coset space. They acquire masses, and therefore become pseudo-Goldstone bosons, due...... of the theory, the quantum corrections are precisely calculable. The remaining pseudo-Goldstone boson is identified with the dark matter candidate because it is neutral with respect to the Standard Model and stable. By a direct comparison with the Large Hadron Collider experiments, the model is found...... to be phenomenologically viable. Furthermore the dark matter particle leads to the observed thermal relic density while respecting the most stringent current experimental constraints....

  4. Causality discovery technology

    Science.gov (United States)

    Chen, M.; Ertl, T.; Jirotka, M.; Trefethen, A.; Schmidt, A.; Coecke, B.; Bañares-Alcántara, R.

    2012-11-01

    Causality is the fabric of our dynamic world. We all make frequent attempts to reason causation relationships of everyday events (e.g., what was the cause of my headache, or what has upset Alice?). We attempt to manage causality all the time through planning and scheduling. The greatest scientific discoveries are usually about causality (e.g., Newton found the cause for an apple to fall, and Darwin discovered natural selection). Meanwhile, we continue to seek a comprehensive understanding about the causes of numerous complex phenomena, such as social divisions, economic crisis, global warming, home-grown terrorism, etc. Humans analyse and reason causality based on observation, experimentation and acquired a priori knowledge. Today's technologies enable us to make observations and carry out experiments in an unprecedented scale that has created data mountains everywhere. Whereas there are exciting opportunities to discover new causation relationships, there are also unparalleled challenges to benefit from such data mountains. In this article, we present a case for developing a new piece of ICT, called Causality Discovery Technology. We reason about the necessity, feasibility and potential impact of such a technology.

  5. Inside CERN's Large Hadron Collider from the proton to the Higgs boson

    CERN Document Server

    Campanelli, Mario

    2016-01-01

    The book aims to explain the historical development of particle physics, with special emphasis on CERN and collider physics. It describes in detail the LHC accelerator and its detectors, describing the science involved as well as the sociology of big collaborations, culminating with the discovery of the Higgs boson. Readers are led step-by-step to understanding why we do particle physics, as well as the tools and problems involved in the field. It provides an insider's view on the experiments at the Large Hadron Collider.

  6. Can Family Gauge Bosons Be Visible by Terrestrial Experiments?

    CERN Document Server

    Koide, Yoshio

    2015-01-01

    It is investigated whether observations of family gauge bosons by terrestrial experiments are possible or not. We propose an extended version of Sumino's family gauge boson model based on U(3) family symmetry. Then, we can expect the lowest family gauge boson $A_1^1$ with $M \\sim 4.3$ TeV.

  7. FAST TRACK COMMUNICATION: Quantization over boson operator spaces

    Science.gov (United States)

    Prosen, Tomaž; Seligman, Thomas H.

    2010-10-01

    The framework of third quantization—canonical quantization in the Liouville space—is developed for open many-body bosonic systems. We show how to diagonalize the quantum Liouvillean for an arbitrary quadratic n-boson Hamiltonian with arbitrary linear Lindblad couplings to the baths and, as an example, explicitly work out a general case of a single boson.

  8. Search for heavy resonances in vector boson fusion

    CERN Document Server

    Zhang, Guangyi; The ATLAS collaboration

    2016-01-01

    If the Higgs boson discovered at the Large Hadron Collider (LHC) is not exactly the one in the Standard Model, an alternative mechanism is needed to restore unitarity in the scattering amplitude of longitudinal gauge bosons, and new resonances may appear. This paper presents a search for new heavy neutral resonances ($R$) produced through vector boson fusion process $qq \\rightarrow Rqq \\rightarrow \\ell^+ \

  9. On the gauging of chiral bosons

    CERN Document Server

    Wotzasek, C

    1995-01-01

    We study the coupling of chiral bosons to external electromagnetic fields. It is observed that a naive gauging procedure leaves the gauge invariant chirality condition incompatible with the field equations. We propose the use of this feature as a consistency test to select the appropriate way to perform the gauge coupling. We verify that among all the possible gauging schemes, only the coupling of gauge fields with chiral currents passes the consistency test. As an application, we use this gauging scheme to show how the introduction of a gauge field becomes necessary in order to sold together a right and a left chiral boson.

  10. Net tightens round the Higgs boson

    Energy Technology Data Exchange (ETDEWEB)

    Burrows, P. [Particle and Nuclear Physics Laboratory, University of Oxford, Oxford (United Kingdom)

    1999-09-01

    Results presented at the International Europhysics Conference on High Energy Physics in mid-July provide strong hints that the Higgs boson, one of the holy grails of particle physics, is lurking just around the corner. Over 500 physicists gathered in Tampere, Finland, armed with the latest data and hot on the trail of this elusive particle, the interactions of which are thought to be responsible for giving particles their mass. The Higgs boson is the only unobserved piece in the jigsaw puzzle of elementary particles in the Standard Model. And it now appears to be within tantalizing reach of experiments that will take place over the next few years. (UK)

  11. Boson sampling from a Gaussian state.

    Science.gov (United States)

    Lund, A P; Laing, A; Rahimi-Keshari, S; Rudolph, T; O'Brien, J L; Ralph, T C

    2014-09-05

    We pose a randomized boson-sampling problem. Strong evidence exists that such a problem becomes intractable on a classical computer as a function of the number of bosons. We describe a quantum optical processor that can solve this problem efficiently based on a Gaussian input state, a linear optical network, and nonadaptive photon counting measurements. All the elements required to build such a processor currently exist. The demonstration of such a device would provide empirical evidence that quantum computers can, indeed, outperform classical computers and could lead to applications.

  12. Z Boson Pair-Production at LEP

    CERN Document Server

    Achard, P; Aguilar-Benítez, M; Alcaraz, J; Alemanni, G; Allaby, James V; Aloisio, A; Alviggi, M G; Anderhub, H; Andreev, V P; Anselmo, F; Arefev, A; Azemoon, T; Aziz, T; Bagnaia, P; Bajo, A; Baksay, G; Baksay, L; Baldew, S V; Banerjee, S; Banerjee, Sw; Barczyk, A; Barillère, R; Bartalini, P; Basile, M; Batalova, N; Battiston, R; Bay, A; Becattini, F; Becker, U; Behner, F; Bellucci, L; Berbeco, R; Berdugo, J; Berges, P; Bertucci, B; Betev, B L; Biasini, M; Biglietti, M; Biland, A; Blaising, J J; Blyth, S C; Bobbink, Gerjan J; Böhm, A; Boldizsar, L; Borgia, B; Bottai, S; Bourilkov, D; Bourquin, Maurice; Braccini, S; Branson, J G; Brochu, F; Burger, J D; Burger, W J; Cai, X D; Capell, M; Cara Romeo, G; Carlino, G; Cartacci, A M; Casaus, J; Cavallari, F; Cavallo, N; Cecchi, C; Cerrada, M; Chamizo-Llatas, M; Chang, Y H; Chemarin, M; Chen, A; Chen, G; Chen, G M; Chen, H F; Chen, H S; Chiefari, G; Cifarelli, Luisa; Cindolo, F; Clare, I; Clare, R; Coignet, G; Colino, N; Costantini, S; de la Cruz, B; Cucciarelli, S; van Dalen, J A; De Asmundis, R; Déglon, P L; Debreczeni, J; Degré, A; Dehmelt, K; Deiters, K; Della Volpe, D; Delmeire, E; Denes, P; De Notaristefani, F; De Salvo, A; Diemoz, M; Dierckxsens, M; Dionisi, C; Dittmar, M; Doria, A; Dova, M T; Duchesneau, D; Duda, M; Echenard, B; Eline, A; El-Hage, A; El-Mamouni, H; Engler, A; Eppling, F J; Extermann, P; Falagán, M A; Falciano, S; Favara, A; Fay, J; Fedin, O; Felcini, M; Ferguson, T; Fesefeldt, H S; Fiandrini, E; Field, J H; Filthaut, Frank; Fisher, P H; Fisher, W; Fisk, I; Forconi, G; Freudenreich, Klaus; Furetta, C; Galaktionov, Yu; Ganguli, S N; García-Abia, P; Gataullin, M; Gentile, S; Giagu, S; Gong, Z F; Grenier, G; Grimm, O; Grünewald, M W; Guida, M; van Gulik, R; Gupta, V K; Gurtu, A; Gutay, L J; Haas, D; Hatzifotiadou, D; Hebbeker, T; Hervé, A; Hirschfelder, J; Hofer, H; Hohlmann, M; Holzner, G; Hou, S R; Hu, Y; Jin, B N; Jones, L W; de Jong, P; Josa-Mutuberria, I; Käfer, D; Kaur, M; Kienzle-Focacci, M N; Kim, J K; Kirkby, Jasper; Kittel, E W; Klimentov, A; König, A C; Kopal, M; Koutsenko, V F; Kräber, M H; Krämer, R W; Krüger, A; Kunin, A; Ladrón de Guevara, P; Laktineh, I; Landi, G; Lebeau, M; Lebedev, A; Lebrun, P; Lecomte, P; Lecoq, P; Le Coultre, P; Le Goff, J M; Leiste, R; Levtchenko, M; Levchenko, P M; Li, C; Likhoded, S; Lin, C H; Lin, W T; Linde, Frank L; Lista, L; Liu, Z A; Lohmann, W; Longo, E; Lü, Y S; Luci, C; Luminari, L; Lustermann, W; Ma Wen Gan; Malgeri, L; Malinin, A; Maña, C; Mans, J; Martin, J P; Marzano, F; Mazumdar, K; McNeil, R R; Mele, S; Merola, L; Meschini, M; Metzger, W J; Mihul, A; Milcent, H; Mirabelli, G; Mnich, J; Mohanty, G B; Muanza, G S; Muijs, A J M; Musicar, B; Musy, M; Nagy, S; Natale, S; Napolitano, M; Nessi-Tedaldi, F; Newman, H; Nisati, A; Novák, T; Nowak, H; Ofierzynski, R A; Organtini, G; Pal, I; Palomares, C; Paolucci, P; Paramatti, R; Passaleva, G; Patricelli, S; Paul, T; Pauluzzi, M; Paus, C; Pauss, Felicitas; Pedace, M; Pensotti, S; Perret-Gallix, D; Petersen, B; Piccolo, D; Pierella, F; Pioppi, M; Piroué, P A; Pistolesi, E; Plyaskin, V; Pohl, M; Pozhidaev, V; Pothier, J; Prokofev, D; Prokofiev, D O; Quartieri, J; Rahal-Callot, G; Rahaman, M A; Raics, P; Raja, N; Ramelli, R; Rancoita, P G; Ranieri, R; Raspereza, A V; Razis, P A; Ren, D; Rescigno, M; Reucroft, S; Riemann, S; Riles, K; Roe, B P; Romero, L; Rosca, A; Rosier-Lees, S; Roth, S; Rosenbleck, C; Roux, B; Rubio, J A; Ruggiero, G; Rykaczewski, H; Sakharov, A; Saremi, S; Sarkar, S; Salicio, J; Sánchez, E; Schäfer, C; Shchegelskii, V; Schopper, Herwig Franz; Schotanus, D J; Sciacca, C; Servoli, L; Shevchenko, S; Shivarov, N; Shoutko, V; Shumilov, E; Shvorob, A V; Son, D; Souga, C; Spillantini, P; Steuer, M; Stickland, D P; Stoyanov, B; Strässner, A; Sudhakar, K; Sultanov, G G; Sun, L Z; Sushkov, S; Suter, H; Swain, J D; Szillási, Z; Tang, X W; Tarjan, P; Tauscher, Ludwig; Taylor, L; Tellili, B; Teyssier, D; Timmermans, C; Ting, Samuel C C; Ting, S M; Tonwar, S C; Tóth, J; Tully, C; Tung, K L; Ulbricht, J; Valente, E; Van de Walle, R T; Vásquez, R; Veszpremi, V; Vesztergombi, G; Vetlitskii, I; Vicinanza, D; Viertel, Gert M; Villa, S; Vivargent, M; Vlachos, S; Vodopyanov, I; Vogel, H; Vogt, H; Vorobev, I; Vorobyov, A A; Wadhwa, M; Wang, Q; Wang, X L; Wang, Z M; Weber, M; Wienemann, P; Wilkens, H; Wynhoff, S; Xia, L; Xu, Z Z; Yamamoto, J; Yang, B Z; Yang, C G; Yang, H J; Yang, M; Yeh, S C; Zalite, A; Zalite, Yu; Zhang, Z P; Zhao, J; Zhu, G Y; Zhu, R Y; Zhuang, H L; Zichichi, A; Zimmermann, B; Zöller, M

    2003-01-01

    Events stemming from the pair-production of Z bosons in e^+e^- collisions are studied using 217.4 pb^-1 of data collected with the L3 detector at centre-of-mass energies from 200 GeV up to 209 GeV. The special case of events with b quarks is also investigated. Combining these events with those collected at lower centre-of-mass energies, the Standard Model predictions for the production mechanism are verified. In addition, limits are set on anomalous couplings of neutral gauge bosons and on effects of extra space dimensions.

  13. Search for Charged Higgs Bosons at LEP

    CERN Document Server

    Achard, P; Aguilar-Benítez, M; Alcaraz, J; Alemanni, G; Allaby, James V; Aloisio, A; Alviggi, M G; Anderhub, H; Andreev, V P; Anselmo, F; Arefev, A; Azemoon, T; Aziz, T; Bagnaia, P; Bajo, A; Baksay, G; Baksay, L; Baldew, S V; Banerjee, S; Banerjee, Sw; Barczyk, A; Barillère, R; Bartalini, P; Basile, M; Batalova, N; Battiston, R; Bay, A; Becattini, F; Becker, U; Behner, F; Bellucci, L; Berbeco, R; Berdugo, J; Berges, P; Bertucci, B; Betev, B L; Biasini, M; Biglietti, M; Biland, A; Blaising, J J; Blyth, S C; Bobbink, Gerjan J; Böhm, A; Boldizsar, L; Borgia, B; Bottai, S; Bourilkov, D; Bourquin, Maurice; Braccini, S; Branson, J G; Brochu, F; Burger, J D; Burger, W J; Cai, X D; Capell, M; Cara Romeo, G; Carlino, G; Cartacci, A M; Casaus, J; Cavallari, F; Cavallo, N; Cecchi, C; Cerrada, M; Chamizo-Llatas, M; Chang, Y H; Chemarin, M; Chen, A; Chen, G; Chen, G M; Chen, H F; Chen, H S; Chiefari, G; Cifarelli, Luisa; Cindolo, F; Clare, I; Clare, R; Coignet, G; Colino, N; Costantini, S; de la Cruz, B; Cucciarelli, S; van Dalen, J A; De Asmundis, R; Déglon, P L; Debreczeni, J; Degré, A; Dehmelt, K; Deiters, K; Della Volpe, D; Delmeire, E; Denes, P; De Notaristefani, F; De Salvo, A; Diemoz, M; Dierckxsens, M; Dionisi, C; Dittmar, M; Doria, A; Dova, M T; Duchesneau, D; Duda, M; Echenard, B; Eline, A; El-Hage, A; El-Mamouni, H; Engler, A; Eppling, F J; Extermann, P; Falagán, M A; Falciano, S; Favara, A; Fay, J; Fedin, O; Felcini, M; Ferguson, T; Fesefeldt, H S; Fiandrini, E; Field, J H; Filthaut, Frank; Fisher, P H; Fisher, W; Fisk, I; Forconi, G; Freudenreich, Klaus; Furetta, C; Galaktionov, Yu; Ganguli, S N; García-Abia, P; Gataullin, M; Gentile, S; Giagu, S; Gong, Z F; Grenier, G; Grimm, O; Grünewald, M W; Guida, M; van Gulik, R; Gupta, V K; Gurtu, A; Gutay, L J; Haas, D; Hatzifotiadou, D; Hebbeker, T; Hervé, A; Hirschfelder, J; Hofer, H; Hohlmann, M; Holzner, G; Hou, S R; Hu, Y; Jin, B N; Jones, L W; de Jong, P; Josa-Mutuberria, I; Käfer, D; Kaur, M; Kienzle-Focacci, M N; Kim, J K; Kirkby, Jasper; Kittel, E W; Klimentov, A; König, A C; Kopal, M; Koutsenko, V F; Kräber, M H; Krämer, R W; Krüger, A; Kunin, A; Ladrón de Guevara, P; Laktineh, I; Landi, G; Lebeau, M; Lebedev, A; Lebrun, P; Lecomte, P; Lecoq, P; Le Coultre, P; Le Goff, J M; Leiste, R; Levtchenko, M; Levchenko, P M; Li, C; Likhoded, S; Lin, C H; Lin, W T; Linde, Frank L; Lista, L; Liu, Z A; Lohmann, W; Longo, E; Lü, Y S; Luci, C; Luminari, L; Lustermann, W; Ma Wen Gan; Malgeri, L; Malinin, A; Maña, C; Mans, J; Martin, J P; Marzano, F; Mazumdar, K; McNeil, R R; Mele, S; Merola, L; Meschini, M; Metzger, W J; Mihul, A; Milcent, H; Mirabelli, G; Mnich, J; Mohanty, G B; Muanza, G S; Muijs, A J M; Musicar, B; Musy, M; Nagy, S; Natale, S; Napolitano, M; Nessi-Tedaldi, F; Newman, H; Nisati, A; Novák, T; Nowak, H; Ofierzynski, R A; Organtini, G; Pal, I; Palomares, C; Paolucci, P; Paramatti, R; Passaleva, G; Patricelli, S; Paul, T; Pauluzzi, M; Paus, C; Pauss, Felicitas; Pedace, M; Pensotti, S; Perret-Gallix, D; Petersen, B; Piccolo, D; Pierella, F; Pioppi, M; Piroué, P A; Pistolesi, E; Plyaskin, V; Pohl, M; Pozhidaev, V; Pothier, J; Prokofev, D; Prokofiev, D O; Quartieri, J; Rahal-Callot, G; Rahaman, M A; Raics, P; Raja, N; Ramelli, R; Rancoita, P G; Ranieri, R; Raspereza, A V; Razis, P A; Ren, D; Rescigno, M; Reucroft, S; Riemann, S; Riles, K; Roe, B P; Romero, L; Rosca, A; Rosenbleck, C; Rosier-Lees, S; Roth, S; Rubio, J A; Ruggiero, G; Rykaczewski, H; Sakharov, A; Saremi, S; Sarkar, S; Salicio, J; Sánchez, E; Schäfer, C; Shchegelskii, V; Schopper, Herwig Franz; Schotanus, D J; Sciacca, C; Servoli, L; Shevchenko, S; Shivarov, N; Shoutko, V; Shumilov, E; Shvorob, A V; Son, D; Souga, C; Spillantini, P; Steuer, M; Stickland, D P; Stoyanov, B; Strässner, A; Sudhakar, K; Sultanov, G G; Sun, L Z; Sushkov, S; Suter, H; Swain, J D; Szillási, Z; Tang, X W; Tarjan, P; Tauscher, Ludwig; Taylor, L; Tellili, B; Teyssier, D; Timmermans, C; Ting, Samuel C C; Ting, S M; Tonwar, S C; Tóth, J; Tully, C; Tung, K L; Ulbricht, J; Valente, E; Van de Walle, R T; Vásquez, R; Veszpremi, V; Vesztergombi, G; Vetlitskii, I; Vicinanza, D; Viertel, Gert M; Villa, S; Vivargent, M; Vlachos, S; Vodopyanov, I; Vogel, H; Vogt, H; Vorobev, I; Vorobyov, A A; Wadhwa, M; Wang, Q; Wang, X L; Wang, Z M; Weber, M; Wienemann, P; Wilkens, H; Wynhoff, S; Xia, L; Xu, Z Z; Yamamoto, J; Yang, B Z; Yang, C G; Yang, H J; Yang, M; Yeh, S C; Zalite, A; Zalite, Yu; Zhang, Z P; Zhao, J; Zhu, G Y; Zhu, R Y; Zhuang, H L; Zichichi, A; Zimmermann, B; Zöller, M

    2003-01-01

    A search for pair-produced charged Higgs bosons is performed with the L3 detector at LEP using data collected at centre-of-mass energies between 189 and 209GeV, corresponding to an integrated luminosity of 629.4/pb. Decays into a charm and a strange quark or into a tau lepton and its neutrino are considered. No significant excess is observed and lower limits on the mass of the charged Higgs boson are derived at the 95% confidence level. They vary from 76.5 to 82.7GeV, as a function of the H->tv branching ratio.

  14. Usability of Discovery Portals

    NARCIS (Netherlands)

    Bulens, J.D.; Vullings, L.A.E.; Houtkamp, J.M.; Vanmeulebrouk, B.

    2013-01-01

    As INSPIRE progresses to be implemented in the EU, many new discovery portals are built to facilitate finding spatial data. Currently the structure of the discovery portals is determined by the way spatial data experts like to work. However, we argue that the main target group for discovery portals

  15. Search for the Higgs boson decaying into $\\tau$ lepton pairs with the Matrix Element Method and $\\tau$ trigger optimization in the CMS experiment at the LHC

    CERN Document Server

    AUTHOR|(CDS)2083962; Beaudette, Florian; Beaudette, Florian

    2016-01-01

    I performed my thesis work in Particle Physics at the laboratoire Leprince-Ringuet of the Ecole Polytechnique. I have been involved in the analysis of the data produced in the proton-proton collisions at the Large Hadron Collider (CERN) and collected by the CMS experiment. Particle physics is a scientific field which is currently undergoing very important breakthroughs. The discovery of the Higgs boson is a major step forward as the mass of vector bosons are explained through their interactions with the corresponding field. I worked on the newly discovered heavy boson analysis. As its direct coupling to fermions remained to be exhibited, I focused on the search for the Higgs boson decaying in tau lepton pairs. The Higgs decay into tau pairs is the most promising decay channel to measure the couplings between the Standard Model Higgs boson and the fermions. Indeed, this decay channel benefits from a large expected event rate compared to the other leptonic decay modes. The Higgs boson decaying to tau lepton ana...

  16. Search for Heavy Top Quark Partners with Charge 5/3 and Anomalous Higgs $(→b\\overline{b})$ Couplings to Vector Bosons

    CERN Document Server

    AUTHOR|(INSPIRE)INSPIRE-00425797

    In this thesis, we present two searches for new physics performed using the data collected by the CMS experiment at the LHC at two different center of mass energies. In the first part, we present a search for anomalous Higgs couplings. In 2012, the ATLAS and CMS experiments at the LHC discovered a new boson. This discovery completed a long search for the final missing piece of the standard model (SM). The measurements so far confirm that the new boson is consistent with the Higgs boson predicted by the SM. However, there are decay channels that are yet to be confirmed experimentally; e.g., the decay to a pair of bottom quarks. In addition, precision measurements of the Higgs couplings to all SM particles need to be performed in order to make sure there is no deviation from the predictions of the SM. We present the first search at the LHC for anomalous couplings of the Higgs boson H to vector bosons V (= W or Z) using associated Higgs production with the Higgs boson decaying to a pair of bottom quarks. We use...

  17. Search for the Standard Model Higgs boson at D0 in the $\\mu~+~\\tau({\\rm hadrons})~+~{\\rm 2\\ jets}$ final state

    Energy Technology Data Exchange (ETDEWEB)

    Ye, Wanyu [State Univ. of New York (SUNY), Stony Brook, NY (United States)

    2012-12-01

    The Standard Model has been a successful theory in various aspects. It predicted and led to discovery of many new particles, including the Higgs boson recently found, the last missing piece of the Standard Model. The Higgs mechanism allows the vector bosons and fermions to be massive via the electroweak symmetry breaking. This dissertation presents the search of the Standard Model Higgs through the decay products: one muon, one hadronically decaying tau, and two or more jets using the full 9.7 fb$^{-1}$ of Tevatron collider Run II data set collected in the Dzero detector at Fermilab. The main production channels are gluon-gluon fusion, vector boson fusion, and Higgs production associated with a $W/Z$ boson. No evidence of the Standard Model Higgs boson is observed in these channels with hypothesized Higgs mass between 105 GeV and 150 GeV, but the data do not exclude it either. We set the upper limits on the ratio of the 95% CL exclusion to the SM Higgs cross section. Combining with other analyses in Tevatron, the Higgs mass is ruled out at 95 % confidence level between 147 and 180 GeV, and a 2.9 $\\sigma$ excess of events indicates a Higgs boson possibly lies in the mass range from 115 to 140 GeV.

  18. Prospects for Discovering the Higgs-like Pseudo-Nambu-Goldstone Boson of the Classical Scale Symmetry

    CERN Document Server

    Farzinnia, Arsham

    2015-01-01

    We examine the impact of the expected reach of the LHC and the XENON1T experiments on the parameter space of the minimal classically scale invariant extension of the standard model (SM), where all the mass scales are induced dynamically by means of the Coleman-Weinberg mechanism. In this framework, the SM content is enlarged by the addition of one complex gauge singlet scalar with a scale invariant and $CP$-symmetric potential. The massive pseudoscalar component, protected by the $CP$-symmetry, forms a viable dark matter candidate, and three flavors of the right-handed Majorana neutrinos are included to account for the nonzero masses of the SM neutrinos via the see-saw mechanism. The projected constraints on the parameter space arise by applying the ATLAS heavy Higgs discovery prospects, with an integrated luminosity of 300 and 3000 fb$^{-1}$ at $\\sqrt s = 14$ TeV, to the pseudo-Nambu-Goldstone boson of the (approximate) scale symmetry, as well as by utilizing the expected reach of the XENON1T direct detectio...

  19. Modeling small dark energy scale with quintessential pseudoscalar boson

    CERN Document Server

    Kim, Jihn E

    2013-01-01

    Democracy among the same type of particles is a useful paradigm in studying masses and interactions of particles with supersymmetry(SUSY) or without SUSY. This simple idea predicts the presence of massless particles. We attempt to use one of these massless pseudoscalar particles as generating the cosmological dark energy(DE) potential. To achieve the extremely shallow potential of DE, the pseudoscalar boson is required not to couple to the QCD anomaly. So, we consider two pseudoscalars, one coupling to the QCD anomaly (i.e. QCD axion) and the other not coupling to the QCD anomaly. To obtain these two pseudoscalars, we introduce two approximate global U(1) symmetries to realize them as the pseudo-Goldstone bosons of the spontaneously broken U(1)'s. These global symmetries are dictated by a gravity respected discrete symmetry. Specifically, we consider an S2(L) X S2(R) X Z(10R) example, and attempt to obtain the DE scale in terms of two observed fundamental mass scales, the Planck scale M(P) and the electroweak...

  20. Backgrounds To Higgs Boson Searches from Asymmetric Internal Conversion

    CERN Document Server

    Gray, Richard C; Park, Michael; Somalwar, Sunil; Thomas, Scott

    2011-01-01

    A class of potential backgrounds for Higgs boson searches in the W W to di-lepton channel at both the Tevatron and Large Hadron Collider is presented. Backgrounds from W photon production with external conversion of the on-shell photon in detector material to an asymmetric electron-positron pair, with loss of the trailing electron or positron has been treated adequately in Higgs searches. Here we consider analogous backgrounds from the production of a W with an off-shell photon and with the internal conversion of the off-shell photon in vacuum to an asymmetric lepton-anti-lepton pair. While the former process yields almost entirely electrons or positrons, the latter can give electron, positron, muon, and anti-muon backgrounds in roughly equal amounts. We estimate that asymmetric internal conversion backgrounds are comparable to the Higgs boson signal in the standard signal region of phase space. These processes also represent potential backgrounds for new physics searches in same-sign di-lepton channels. Some...

  1. Exact Solution for Jaynes-Cummings Model with Bosonic Field Nonlinearity and Strong Boson-Fermion Coupling

    Institute of Scientific and Technical Information of China (English)

    YANG Jin; YU Wan-Lun; XIANG An-Ping

    2006-01-01

    We use Lewis-Riesenfeld invariant approach to treat the modified Jaynes-Cummings models involving any forms of nonlinearty of the bosonic field when strong boson-fermion couplings are nilpotent Grassmann valued. The general state functions, time evolution operator and the time-evolution expressions for both the bosonic number and the fermionic number are presented.

  2. Discovery of novel enzymes with industrial potential from a cold and alkaline environment by a combination of functional metagenomics and culturing

    DEFF Research Database (Denmark)

    Vester, Jan Kjølhede; Glaring, Mikkel Andreas; Stougaard, Peter

    2014-01-01

    complemented each other by targeting different microbial communities, highlighting the usefulness of combining methods for bioprospecting. Finally, we document here that ikaite columns constitute an important source of cold- and/or alkaline-active enzymes with industrial application potential. © 2014 Vester et...

  3. Exploring the effect of N-substitution in nor-lobelane on the interaction with VMAT2: discovery of a potential clinical candidate for treatment of methamphetamine abuse.

    Science.gov (United States)

    Zheng, Guangrong; Horton, David B; Penthala, Narsimha Reddy; Nickell, Justin R; Culver, John P; Deaciuc, Agripina G; Dwoskin, Linda P; Crooks, Peter A

    2013-03-01

    A series of N-substituted lobelane analogues was synthesized and evaluated for their [(3)H]dihydrotetrabenazine binding affinity at the vesicular monoamine transporter and for their inhibition of vesicular [(3)H]dopamine uptake. Compound 19a, which contains an N-1,2(R)-dihydroxypropyl group, had been identified as a potential clinical candidate for the treatment of methamphetamine abuse.

  4. Tunneling dynamics in open ultracold bosonic systems. Numerically exact dynamics - Analytical models - Control schemes

    Energy Technology Data Exchange (ETDEWEB)

    Lode, Axel U.J.

    2013-06-03

    This thesis explores the quantum many-body tunneling dynamics of open ultracold bosonic systems with the recently developed multiconfigurational time-dependent Hartree for bosons (MCTDHB) method. The capabilities of MCTDHB to provide solutions to the full time-dependent many-body problem are assessed in a benchmark using the analytically solvable harmonic interaction Hamiltonian and a generalization of it with time-dependent both one- and two-body potentials. In a comparison with numerically exact MCTDHB results, it is shown that e.g. lattice methods fail qualitatively to describe the tunneling dynamics. A model assembling the many-body physics of the process from basic simultaneously happening single-particle processes is derived and verified with a numerically exact MCTDHB description. The generality of the model is demonstrated even for strong interactions and large particle numbers. The ejection of the bosons from the source occurs with characteristic velocities. These velocities are defined by the chemical potentials of systems with different particle numbers which are converted to kinetic energy. The tunneling process is accompanied by fragmentation: the ejected bosons lose their coherence with the source and among each other. It is shown that the various aspects of the tunneling dynamics' can be controlled well with the interaction and the potential threshold.

  5. Search for Charged Higgs Bosons decaying via H+ -> tau nu in 7TeV pp Collisions with the ATLAS Detector

    CERN Document Server

    Kopp, Anna; The ATLAS collaboration

    2012-01-01

    This poster summarizes the searches for charged Higgs bosons using an integrated luminosity of up to 5/fb recorded with the ATLAS detector at the LHC at sqrt(s)=7 TeV centre-of-mass energy. The discovery of a charged Higgs boson would be an unambiguous sign of physics beyond the Standard Model. Recent studies are introduced, results are reported and exclusion limits are given as a function of the production cross section and interpreted in the context of the Minimal Supersymmetric extension of the Standard Model.

  6. Search for the Higgs boson in the ZH to ℓ+-b$\\bar{b}$ channel at CDF Run II

    Energy Technology Data Exchange (ETDEWEB)

    Efron, Jonathan Zvi [The Ohio State Univ., Columbus, OH (United States)

    2007-01-01

    The Standard Model of particle physics is in excellent agreement with the observed phenomena of particle physics. Within the Standard Model, the weak and electromagnetic forces are successfully combined. However, this combination is only valid if the masses of the force carriers of the weak force, the Z and W bosons, are massless. In fact, these two particles are the second and third most massive observed elementary particles. Within the minimal Standard Model, the Higgs mechanism is introduced to reconcile this contradiction. Conclusive proof of this theory would come with the discovery of the Higgs boson.

  7. Recent multi-boson and vector-boson scattering measurements from ATLAS

    CERN Document Server

    Spettel, Fabian; The ATLAS collaboration

    2016-01-01

    Recent multi-boson and vector-boson scattering measurements from ATLAS Measurements of the cross sections of the production of multiple electroweak gauge bosons constitute stringent tests of the electroweak sector of the Standard Model and provide a model-independent means to search for new physics at the TeV scale. We present recent measurements of the inclusive and differential cross sections for WW, WZ, Z+photon, WWW, Z+2photons, exclusive WW and electroweak production of single W or Z bosons at pp collision energies of 8 TeV and 13 TeV. Distributions sensitive to anomalous triple or quartic gauge couplings have been studied and limits on new physics have been derived.

  8. Measurement of Triple-Gauge-Boson Couplings of the W Boson at LEP

    CERN Document Server

    Acciarri, M; Adriani, O; Aguilar-Benítez, M; Alcaraz, J; Alemanni, G; Allaby, James V; Aloisio, A; Alviggi, M G; Ambrosi, G; Anderhub, H; Andreev, V P; Angelescu, T; Anselmo, F; Arefev, A; Azemoon, T; Aziz, T; Bagnaia, P; Baksay, L; Balandras, A; Ball, R C; Banerjee, S; Banerjee, Sw; Barczyk, A; Barillère, R; Barone, L; Bartalini, P; Basile, M; Battiston, R; Bay, A; Becattini, F; Becker, U; Behner, F; Bellucci, L; Berdugo, J; Berges, P; Bertucci, B; Betev, B L; Bhattacharya, S; Biasini, M; Biland, A; Blaising, J J; Blyth, S C; Bobbink, Gerjan J; Böhm, A; Boldizsar, L; Borgia, B; Bourilkov, D; Bourquin, Maurice; Braccini, S; Branson, J G; Brigljevic, V; Brochu, F; Buffini, A; Buijs, A; Burger, J D; Burger, W J; Busenitz, J K; Button, A M; Cai, X D; Campanelli, M; Capell, M; Cara Romeo, G; Carlino, G; Cartacci, A M; Casaus, J; Castellini, G; Cavallari, F; Cavallo, N; Cecchi, C; Cerrada-Canales, M; Cesaroni, F; Chamizo-Llatas, M; Chang, Y H; Chaturvedi, U K; Chemarin, M; Chen, A; Chen, G; Chen, G M; Chen, H F; Chen, H S; Chéreau, X J; Chiefari, G; Cifarelli, Luisa; Cindolo, F; Civinini, C; Clare, I; Clare, R; Coignet, G; Colijn, A P; Colino, N; Costantini, S; Cotorobai, F; Cozzoni, B; de la Cruz, B; Csilling, Akos; Cucciarelli, S; Dai, T S; van Dalen, J A; D'Alessandro, R; De Asmundis, R; Déglon, P L; Degré, A; Deiters, K; Della Volpe, D; Denes, P; De Notaristefani, F; De Salvo, A; Diemoz, M; Van Dierendonck, D N; Di Lodovico, F; Dionisi, C; Dittmar, Michael; Dominguez, A; Doria, A; Dova, M T; Duchesneau, D; Duensing, S; Dufournaud, D; Duinker, P; Durán, I; El-Mamouni, H; Engler, A; Eppling, F J; Erné, F C; Extermann, Pierre; Fabre, M; Faccini, R; Falagán, M A; Falciano, S; Favara, A; Fay, J; Fedin, O; Felcini, Marta; Ferguson, T; Ferroni, F; Fesefeldt, H S; Fiandrini, E; Field, J H; Filthaut, Frank; Fisher, P H; Fisk, I; Forconi, G; Fredj, L; Freudenreich, Klaus; Furetta, C; Galaktionov, Yu; Ganguli, S N; García-Abia, P; Gataullin, M; Gau, S S; Gentile, S; Gheordanescu, N; Giagu, S; Gong, Z F; Grenier, G; Grimm, O; Grünewald, M W; Guida, M; van Gulik, R; Gupta, V K; Gurtu, A; Gutay, L J; Haas, D; Hasan, A; Hatzifotiadou, D; Hebbeker, T; Hervé, A; Hidas, P; Hirschfelder, J; Hofer, H; Holzner, G; Hoorani, H; Hou, S R; Iashvili, I; Jin, B N; Jones, L W; de Jong, P; Josa-Mutuberria, I; Khan, R A; Kamrad, D; Kaur, M; Kienzle-Focacci, M N; Kim, D; Kim, D H; Kim, J K; Kim, S C; Kirkby, Jasper; Kiss, D; Kittel, E W; Klimentov, A; König, A C; Kopp, A; Korolko, I; Koutsenko, V F; Kräber, M H; Krämer, R W; Krenz, W; Kunin, A; Ladrón de Guevara, P; Laktineh, I; Landi, G; Lassila-Perini, K M; Laurikainen, P; Lavorato, A; Lebeau, M; Lebedev, A; Lebrun, P; Lecomte, P; Lecoq, P; Le Coultre, P; Lee, H J; Le Goff, J M; Leiste, R; Leonardi, E; Levchenko, P M; Li Chuan; Lin, C H; Lin, W T; Linde, Frank L; Lista, L; Liu, Z A; Lohmann, W; Longo, E; Lü, Y S; Lübelsmeyer, K; Luci, C; Luckey, D; Lugnier, L; Luminari, L; Lustermann, W; Ma Wen Gan; Maity, M; Malgeri, L; Malinin, A; Maña, C; Mangeol, D J J; Marchesini, P A; Marian, G; Martin, J P; Marzano, F; Massaro, G G G; Mazumdar, K; McNeil, R R; Mele, S; Merola, L; Meschini, M; Metzger, W J; Von der Mey, M; Mihul, A; Milcent, H; Mirabelli, G; Mnich, J; Mohanty, G B; Molnár, P; Monteleoni, B; Moulik, T; Muanza, G S; Muheim, F; Muijs, A J M; Musy, M; Napolitano, M; Nessi-Tedaldi, F; Newman, H; Niessen, T; Nisati, A; Nowak, H; Oh, Yu D; Organtini, G; Ostonen, R; Palomares, C; Pandoulas, D; Paoletti, S; Paolucci, P; Paramatti, R; Park, H K; Park, I H; Pascale, G; Passaleva, G; Patricelli, S; Paul, T; Pauluzzi, M; Paus, C; Pauss, Felicitas; Peach, D; Pedace, M; Pensotti, S; Perret-Gallix, D; Petersen, B; Piccolo, D; Pierella, F; Pieri, M; Piroué, P A; Pistolesi, E; Plyaskin, V; Pohl, M; Pozhidaev, V; Postema, H; Pothier, J; Produit, N; Prokofev, D; Prokofiev, D O; Quartieri, J; Rahal-Callot, G; Rahaman, M A; Raics, P; Raja, N; Ramelli, R; Rancoita, P G; Raven, G; Razis, P A; Ren, D; Rescigno, M; Reucroft, S; Van Rhee, T; Riemann, S; Riles, K; Robohm, A; Rodin, J; Roe, B P; Romero, L; Rosca, A; Rosier-Lees, S; Rubio, Juan Antonio; Ruschmeier, D; Rykaczewski, H; Saremi, S; Sarkar, S; Salicio, J; Sánchez, E; Sanders, M P; Sarakinos, M E; Schäfer, C; Shchegelskii, V; Schmidt-Kärst, S; Schmitz, D; Schopper, Herwig Franz; Schotanus, D J; Schwering, G; Sciacca, C; Sciarrino, D; Seganti, A; Servoli, L; Shevchenko, S; Shivarov, N; Shoutko, V; Shumilov, E; Shvorob, A V; Siedenburg, T; Son, D; Smith, B; Spillantini, P; Steuer, M; Stickland, D P; Stone, A; Stone, H; Stoyanov, B; Strässner, A; Sudhakar, K; Sultanov, G G; Sun, L Z; Suter, H; Swain, J D; Szillási, Z; Sztaricskai, T; Tang, X W; Tauscher, Ludwig; Taylor, L; Timmermans, C; Ting, Samuel C C; Ting, S M; Tonwar, S C; Tóth, J; Tully, C; Tung, K L; Uchida, Y; Ulbricht, J; Valente, E; Vesztergombi, G; Vetlitskii, I; Vicinanza, D; Viertel, Gert M; Villa, S; Vivargent, M; Vlachos, S; Vodopyanov, I; Vogel, H; Vogt, H; Vorobev, I; Vorobyov, A A; Vorvolakos, A; Wadhwa, M; Wallraff, W; Wang, M; Wang, X L; Wang, Z M; Weber, A; Weber, M; Wienemann, P; Wilkens, H; Wu, S X; Wynhoff, S; Xia, L; Xu, Z Z; Yang, B Z; Yang, C G; Yang, H J; Yang, M; Ye, J B; Yeh, S C; Zalite, A; Zalite, Yu; Zhang, Z P; Zhu, G Y; Zhu, R Y; Zichichi, A; Ziegler, F; Zilizi, G; Zöller, M

    1999-01-01

    We report on measurements of the triple-gauge-boson couplings of the W boson in $\\mathrm{e^+e^-}$ collisions with the L3 detector at LEP. W-pair, single-W and single-photon events are analysed in a data sample corresponding to a total luminosity of 76.7~pb$^{-1}$ collected at centre-of-mass energies between 161~GeV and 183~GeV. CP-conserving as well as both C- and P-conserving triple-gauge-boson couplings are determined. The results, in good agreement with the Standard-Model expectations, confirm the existence of the self coupling among the electroweak gauge bosons and constrain its structure.

  9. Higgs boson couplings to bosons with the ATLAS detector: run 1 legacy

    CERN Document Server

    Petit, Elisabeth; The ATLAS collaboration

    2015-01-01

    The final ATLAS measurements of Higgs boson production and couplings in the decay channels $H \\rightarrow ZZ^{(*)} \\rightarrow \\ell\\ell\\ell\\ell$, $H \\rightarrow \\gamma\\gamma$ and $H \\rightarrow WW^{(*)} \\rightarrow \\ell\

  10. Boson Stars in a Theory of Complex Scalar Field coupled to Gravity

    CERN Document Server

    Kumar, Sanjeev; Kulshreshtha, Daya Shankar

    2016-01-01

    We study boson stars in a theory of complex scalar field coupled to Einstein gravity with the potential: $V(|\\Phi|) := m^{2} |\\Phi|^2 +2 \\lambda |\\Phi|$ (where $m^2$ and $\\lambda$ are positive constant parameters). This could be considered either as a theory of massive complex scalar field coupled to gravity in a conical potential or as a theory in the presence of a potential which is an overlap of a parabolic and a conical potential. We study our theory with positive as well as negative values of the cosmological constant $\\Lambda$. Boson stars are found to come in two types, having either ball-like or shell-like charge density. We have studied the properties of these solutions and have also determined their domains of existence for some specific values of the parameters of the theory. Similar solutions have also been obtained by Hartmann, Kleihaus, Kunz, and Schaffer, in a V-shaped scalar potential.

  11. MC@NLO for the hadronic decay of Higgs bosons in associated production with vector bosons

    CERN Document Server

    Latunde-Dada, Oluseyi

    2009-01-01

    In this article we describe simulations of the hadronic decay of Higgs bosons produced in association with vector bosons at linear and hadronic colliders. We use the Monte Carlo at next-to-leading-order MC@NLO matching prescription with the Herwig++ event generator to predict various spectra of the resulting b anti-b pairs and compare our results with leading order and matrix element correction predictions.

  12. Properties of the Higgs boson with the H $\\rightarrow$ ZZ $\\rightarrow$ 4 leptons channel

    CERN Document Server

    Ochando, Christophe

    2013-01-01

    On 2012 July 4th, the ATLAS and CMS experiments reported the discovery of a new boson. The measurement of its properties is now of prime interest to determine whether its the standard model (SM) Higgs or not. In the X$\\rightarrow$ ZZ$\\rightarrow$ 4 leptons (electrons or muons) channel, the final state can be fully reconstructed and with high precision, thanks to the excellent performances of the CMS detector. It therefore offers a unique opportunity to precisely measure the properties of the new boson. The analysis reported here uses pp collisions data recorded by the CMS experiment at the LHC, corresponding to the full Run I statistics (5.1 fb$^{-1}$ at $\\sqrt{s}$=7 TeV, 19.6 fb$^{-1}$ at $\\sqrt{s}$=8 TeV). The mass of the new boson is measured. The spin-parity state is studied using Matrix Element methods, where the SM Higgs hypothesis is confronted to other spin-parity hypothesis. Measurement of the cross-sections, relative the SM expectations, from the different production modes, either via fermions (gl...

  13. First measurement of the associated production of a Z boson with b jets at the LHC

    CERN Document Server

    Ceard, Ludivine

    2015-01-01

    The start of the LHC in 2009 opened a new era in particle physics. The collisions, produced at an energy and a rate unequalled, allowing to probe energysectors and rare processes so far inaccessible. In summer 2012 the announcement of the discovery a new boson, presenting the properties of the long-soughtHiggs boson was confirming the last prediction of the particle physics theoretical framework called the standard model. This theory, even though highlypredictive and never defeated experimentally, is known to have limitations andlacks explanation for several physics observations.The production of a Z boson in association with b jets is a process for which different theoretical predictions from the standard model differ, depending on thetreatment of the b jets in the calculation (so-called 4- and 5-flavour schemes).The measurement of the Z plus b jets cross section and the study of its kinematics constitute then a strong QCD test. The Z plus at least two b jets processconstitutes the main background for stu...

  14. The second Kaluza-Klein neutral Higgs bosons in the minimal Universal Extra Dimension model

    CERN Document Server

    Chang, Sanghyeon; Song, Jeonghyeon

    2011-01-01

    Loop-induced decays of a neutral Higgs boson into a pair of gluon or photon have great implications for the Higgs discovery at the LHC. If the Higgs boson is heavy with mass above $\\sim 500\\gev$, however, these radiative branching ratios are very suppressed in the standard model, as the new decay channels are kinematically open. We note that these radiative decays can be sizable for the heavy second Kaluza-Klein (KK) CP-even $h^\\tw$ and CP-odd $\\chi^\\tw$ modes of the Higgs boson in the minimal universal extra dimension (mUED) model with the KK parity conservation: highly degenerate mass spectrum of the theory prohibits kinematically the dominant KK-number conserving decays into the first KK modes of the $W$, $Z$ and top quark. We find that $h^{(2)} \\to g g$ is absent at one loop level since $h^{(2)}$ couples with different mass eigenstates of $t_{1,2}^\\on$ while the gluon with the same mass eigenstates. The $h^\\tw$ production at the LHC is very suppressed. On the contrary, we have ${\\rm BR} (\\chi^\\tw \\to g g)...

  15. A search for charged Higgs boson with the ATLAS detector at the LHC

    CERN Document Server

    AUTHOR|(CDS)2091211

    This dissertation considers the search for a charged Higgs boson (H±) in proton-proton collisions with centre-of-mass energies of 7 TeV and 8 TeV, using data collected by the ATLAS experiment at the Large Hadron Collider at CERN. The discovery of such a charged Higgs boson would be a clear indication for physics beyond the Standard Model. The first data collected during the LHC Run-I is analysed, searching for a heavy charged Higgs bosons (above the top quark mass). This study covers the gb -> tH± ->ttb where one top-quark decays leptonically and the other decays hadronically. A significant background originating from tt ̄ processes, in addition to others, may conceal the charged Higgs decay in the data. Methods using boosted decision trees to con- strain such backgrounds and provide signal to background discrimination are presented. Upper limits on the production cross section times branching ratio of H± are derived for the mass range of 200 GeV <=mH± <= 600 GeV for six MSSM benchmark scenarios.

  16. Higgs boson studies at the Tevatron

    Science.gov (United States)

    Aaltonen, T.; Abazov, V. M.; Abbott, B.; Acharya, B. S.; Adams, M.; Adams, T.; Agnew, J. P.; Alexeev, G. D.; Alkhazov, G.; Alton, A.; Amerio, S.; Amidei, D.; Anastassov, A.; Annovi, A.; Antos, J.; Apollinari, G.; Appel, J. A.; Arisawa, T.; Artikov, A.; Asaadi, J.; Ashmanskas, W.; Askew, A.; Atkins, S.; Auerbach, B.; Augsten, K.; Aurisano, A.; Avila, C.; Azfar, F.; Badaud, F.; Badgett, W.; Bae, T.; Bagby, L.; Baldin, B.; Bandurin, D. V.; Banerjee, S.; Barbaro-Galtieri, A.; Barberis, E.; Baringer, P.; Barnes, V. E.; Barnett, B. A.; Barria, P.; Bartlett, J. F.; Bartos, P.; Bassler, U.; Bauce, M.; Bazterra, V.; Bean, A.; Bedeschi, F.; Begalli, M.; Behari, S.; Bellantoni, L.; Bellettini, G.; Bellinger, J.; Benjamin, D.; Beretvas, A.; Beri, S. B.; Bernardi, G.; Bernhard, R.; Bertram, I.; Besançon, M.; Beuselinck, R.; Bhat, P. C.; Bhatia, S.; Bhatnagar, V.; Bhatti, A.; Bland, K. R.; Blazey, G.; Blessing, S.; Bloom, K.; Blumenfeld, B.; Bocci, A.; Bodek, A.; Boehnlein, A.; Boline, D.; Boos, E. E.; Borissov, G.; Bortoletto, D.; Boudreau, J.; Boveia, A.; Brandt, A.; Brandt, O.; Brigliadori, L.; Brock, R.; Bromberg, C.; Bross, A.; Brown, D.; Brucken, E.; Budagov, J.; Bu, X. B.; Budd, H. S.; Buehler, M.; Buescher, V.; Bunichev, V.; Burdin, S.; Burkett, K.; Busetto, G.; Bussey, P.; Buszello, C. P.; Butti, P.; Buzatu, A.; Calamba, A.; Camacho-Pérez, E.; Camarda, S.; Campanelli, M.; Canelli, F.; Carls, B.; Carlsmith, D.; Carosi, R.; Carrillo, S.; Casal, B.; Casarsa, M.; Casey, B. C. K.; Castilla-Valdez, H.; Castro, A.; Catastini, P.; Caughron, S.; Cauz, D.; Cavaliere, V.; Cavalli-Sforza, M.; Cerri, A.; Cerrito, L.; Chakrabarti, S.; Chan, K. M.; Chandra, A.; Chapon, E.; Chen, G.; Chen, Y. C.; Chertok, M.; Chiarelli, G.; Chlachidze, G.; Cho, K.; Cho, S. W.; Choi, S.; Chokheli, D.; Choudhary, B.; Cihangir, S.; Ciocci, M. A.; Claes, D.; Clark, A.; Clarke, C.; Clutter, J.; Convery, M. E.; Conway, J.; Cooke, M.; Cooper, W. E.; Corbo, M.; Corcoran, M.; Cordelli, M.; Couderc, F.; Cousinou, M.-C.; Cox, C. A.; Cox, D. J.; Cremonesi, M.; Cruz, D.; Cuevas, J.; Culbertson, R.; Cutts, D.; d'Ascenzo, N.; Das, A.; Datta, M.; Davies, G.; De Barbaro, P.; de Jong, S. J.; De La Cruz-Burelo, E.; Déliot, F.; Demina, R.; Demortier, L.; Deninno, M.; Denisov, D.; Denisov, S. P.; d'Errico, M.; Desai, S.; Deterre, C.; DeVaughan, K.; Devoto, F.; Di Canto, A.; Di Ruzza, B.; Diehl, H. T.; Diesburg, M.; Ding, P. F.; Dittmann, J. R.; Dominguez, A.; Donati, S.; D'Onofrio, M.; Dorigo, M.; Driutti, A.; Dubey, A.; Dudko, L. V.; Duperrin, A.; Dutt, S.; Eads, M.; Ebina, K.; Edgar, R.; Edmunds, D.; Elagin, A.; Ellison, J.; Elvira, V. D.; Enari, Y.; Erbacher, R.; Errede, S.; Esham, B.; Eusebi, R.; Evans, H.; Evdokimov, V. N.; Facini, G.; Farrington, S.; Fauré, A.; Feng, L.; Ferbel, T.; Fernández Ramos, J. P.; Fiedler, F.; Field, R.; Filthaut, F.; Fisher, W.; Fisk, H. E.; Flanagan, G.; Forrest, R.; Fortner, M.; Fox, H.; Franklin, M.; Freeman, J. C.; Frisch, H.; Fuess, S.; Funakoshi, Y.; Garcia-Bellido, A.; García-González, J. A.; Garfinkel, A. F.; Garosi, P.; Gavrilov, V.; Geng, W.; Gerber, C. E.; Gerberich, H.; Gerchtein, E.; Gershtein, Y.; Giagu, S.; Giakoumopoulou, V.; Gibson, K.; Ginsburg, C. M.; Ginther, G.; Giokaris, N.; Giromini, P.; Giurgiu, G.; Glagolev, V.; Glenzinski, D.; Gold, M.; Goldin, D.; Golossanov, A.; Golovanov, G.; Gomez, G.; Gomez-Ceballos, G.; Goncharov, M.; González López, O.; Gorelov, I.; Goshaw, A. T.; Goulianos, K.; Gramellini, E.; Grannis, P. D.; Greder, S.; Greenlee, H.; Grenier, G.; Grinstein, S.; Gris, Ph.; Grivaz, J.-F.; Grohsjean, A.; Grosso-Pilcher, C.; Group, R. C.; Grünendahl, S.; Grünewald, M. W.; Guillemin, T.; Guimaraes da Costa, J.; Gutierrez, G.; Gutierrez, P.; Hahn, S. R.; Haley, J.; Han, J. Y.; Han, L.; Happacher, F.; Hara, K.; Harder, K.; Hare, M.; Harel, A.; Harr, R. F.; Harrington-Taber, T.; Hatakeyama, K.; Hauptman, J. M.; Hays, C.; Hays, J.; Head, T.; Hebbeker, T.; Hedin, D.; Hegab, H.; Heinrich, J.; Heinson, A. P.; Heintz, U.; Hensel, C.; Heredia-De La Cruz, I.; Herndon, M.; Herner, K.; Hesketh, G.; Hildreth, M. D.; Hirosky, R.; Hoang, T.; Hobbs, J. D.; Hocker, A.; Hoeneisen, B.; Hogan, J.; Hohlfeld, M.; Holzbauer, J. L.; Hong, Z.; Hopkins, W.; Hou, S.; Howley, I.; Hubacek, Z.; Hughes, R. E.; Husemann, U.; Hussein, M.; Huston, J.; Hynek, V.; Iashvili, I.; Ilchenko, Y.; Illingworth, R.; Introzzi, G.; Iori, M.; Ito, A. S.; Ivanov, A.; Jabeen, S.; Jaffré, M.; James, E.; Jang, D.; Jayasinghe, A.; Jayatilaka, B.; Jeon, E. J.; Jeong, M. S.; Jesik, R.; Jiang, P.; Jindariani, S.; Johns, K.; Johnson, E.; Johnson, M.; Jonckheere, A.; Jones, M.; Jonsson, P.; Joo, K. K.; Joshi, J.; Jun, S. Y.; Jung, A. W.; Junk, T. R.; Juste, A.; Kajfasz, E.; Kambeitz, M.; Kamon, T.; Karchin, P. E.; Karmanov, D.; Kasmi, A.; Kato, Y.; Katsanos, I.; Kehoe, R.; Kermiche, S.; Ketchum, W.; Keung, J.; Khalatyan, N.; Khanov, A.; Kharchilava, A.; Kharzheev, Y. N.; Kilminster, B.; Kim, D. H.; Kim, H. S.; Kim, J. E.; Kim, M. J.; Kim, S. B.; Kim, S. H.; Kim, Y. J.; Kim, Y. K.; Kimura, N.; Kirby, M.; Kiselevich, I.; Knoepfel, K.; Kohli, J. M.; Kondo, K.; Kong, D. J.; Konigsberg, J.; Kotwal, A. V.; Kozelov, A. V.; Kraus, J.; Kreps, M.; Kroll, J.; Kruse, M.; Kuhr, T.; Kumar, A.; Kupco, A.; Kurata, M.; Kurča, T.; Kuzmin, V. A.; Laasanen, A. T.; Lammel, S.; Lammers, S.; Lancaster, M.; Lannon, K.; Latino, G.; Lebrun, P.; Lee, H. S.; Lee, H. S.; Lee, J. S.; Lee, S. W.; Lee, W. M.; Lei, X.; Lellouch, J.; Leo, S.; Leone, S.; Lewis, J. D.; Li, D.; Li, H.; Li, L.; Li, Q. Z.; Lim, J. K.; Limosani, A.; Lincoln, D.; Linnemann, J.; Lipaev, V. V.; Lipeles, E.; Lipton, R.; Lister, A.; Liu, H.; Liu, H.; Liu, Q.; Liu, T.; Liu, Y.; Lobodenko, A.; Lockwitz, S.; Loginov, A.; Lokajicek, M.; Lopes de Sa, R.; Lucchesi, D.; Lueck, J.; Lujan, P.; Lukens, P.; Luna-Garcia, R.; Lungu, G.; Lyon, A. L.; Lys, J.; Lysak, R.; Maciel, A. K. A.; Madar, R.; Madrak, R.; Maestro, P.; Magaña-Villalba, R.; Malik, S.; Malik, S.; Malyshev, V. L.; Manca, G.; Manousakis-Katsikakis, A.; Mansour, J.; Margaroli, F.; Marino, P.; Martínez, M.; Martínez-Ortega, J.; Matera, K.; Mattson, M. E.; Mazzacane, A.; Mazzanti, P.; McCarthy, R.; McGivern, C. L.; McNulty, R.; Mehta, A.; Mehtala, P.; Meijer, M. M.; Melnitchouk, A.; Menezes, D.; Mercadante, P. G.; Merkin, M.; Mesropian, C.; Meyer, A.; Meyer, J.; Miao, T.; Miconi, F.; Mietlicki, D.; Mitra, A.; Miyake, H.; Moed, S.; Moggi, N.; Mondal, N. K.; Moon, C. S.; Moore, R.; Morello, M. J.; Mukherjee, A.; Mulhearn, M.; Muller, Th.; Murat, P.; Mussini, M.; Nachtman, J.; Nagai, Y.; Naganoma, J.; Nagy, E.; Nakano, I.; Napier, A.; Narain, M.; Nayyar, R.; Neal, H. A.; Negret, J. P.; Nett, J.; Neu, C.; Neustroev, P.; Nguyen, H. T.; Nigmanov, T.; Nodulman, L.; Noh, S. Y.; Norniella, O.; Nunnemann, T.; Oakes, L.; Oh, S. H.; Oh, Y. D.; Oksuzian, I.; Okusawa, T.; Orava, R.; Orduna, J.; Ortolan, L.; Osman, N.; Osta, J.; Pagliarone, C.; Pal, A.; Palencia, E.; Palni, P.; Papadimitriou, V.; Parashar, N.; Parihar, V.; Park, S. K.; Parker, W.; Partridge, R.; Parua, N.; Patwa, A.; Pauletta, G.; Paulini, M.; Paus, C.; Penning, B.; Perfilov, M.; Peters, Y.; Petridis, K.; Petrillo, G.; Pétroff, P.; Phillips, T. J.; Piacentino, G.; Pianori, E.; Pilot, J.; Pitts, K.; Plager, C.; Pleier, M.-A.; Podstavkov, V. M.; Pondrom, L.; Popov, A. V.; Poprocki, S.; Potamianos, K.; Pranko, A.; Prewitt, M.; Price, D.; Prokopenko, N.; Prokoshin, F.; Ptohos, F.; Punzi, G.; Qian, J.; Quadt, A.; Quinn, B.; Ranjan, N.; Ratoff, P. N.; Razumov, I.; Redondo Fernández, I.; Renton, P.; Rescigno, M.; Rimondi, F.; Ripp-Baudot, I.; Ristori, L.; Rizatdinova, F.; Robson, A.; Rodriguez, T.; Rolli, S.; Rominsky, M.; Ronzani, M.; Roser, R.; Rosner, J. L.; Ross, A.; Royon, C.; Rubinov, P.; Ruchti, R.; Ruffini, F.; Ruiz, A.; Russ, J.; Rusu, V.; Sajot, G.; Sakumoto, W. K.; Sakurai, Y.; Sánchez-Hernández, A.; Sanders, M. P.; Santi, L.; Santos, A. S.; Sato, K.; Savage, G.; Saveliev, V.; Savoy-Navarro, A.; Sawyer, L.; Scanlon, T.; Schamberger, R. D.; Scheglov, Y.; Schellman, H.; Schlabach, P.; Schmidt, E. E.; Schwanenberger, C.; Schwarz, T.; Schwienhorst, R.; Scodellaro, L.; Scuri, F.; Seidel, S.; Seiya, Y.; Sekaric, J.; Semenov, A.; Severini, H.; Sforza, F.; Shabalina, E.; Shalhout, S. Z.; Shary, V.; Shaw, S.; Shchukin, A. A.; Shears, T.; Shepard, P. F.; Shimojima, M.; Shochet, M.; Shreyber-Tecker, I.; Simak, V.; Simonenko, A.; Sinervo, P.; Skubic, P.; Slattery, P.; Sliwa, K.; Smirnov, D.; Smith, J. R.; Snider, F. D.; Snow, G. R.; Snow, J.; Snyder, S.; Söldner-Rembold, S.; Song, H.; Sonnenschein, L.; Sorin, V.; Soustruznik, K.; Stancari, M.; St. Denis, R.; Stark, J.; Stelzer, B.; Stelzer-Chilton, O.; Stentz, D.; Stoyanova, D. A.; Strauss, M.; Strologas, J.; Sudo, Y.; Sukhanov, A.; Suslov, I.; Suter, L.; Svoisky, P.; Takemasa, K.; Takeuchi, Y.; Tang, J.; Tecchio, M.; Teng, P. K.; Thom, J.; Thomson, E.; Thukral, V.; Titov, M.; Toback, D.; Tokar, S.; Tokmenin, V. V.; Tollefson, K.; Tomura, T.; Tonelli, D.; Torre, S.; Torretta, D.; Totaro, P.; Trovato, M.; Tsai, Y.-T.; Tsybychev, D.; Tuchming, B.; Tully, C.; Ukegawa, F.; Uozumi, S.; Uvarov, L.; Uvarov, S.; Uzunyan, S.; Van Kooten, R.; van Leeuwen, W. M.; Varelas, N.; Varnes, E. W.; Vasilyev, I. A.; Vázquez, F.; Velev, G.; Vellidis, C.; Verkheev, A. Y.; Vernieri, C.; Vertogradov, L. S.; Verzocchi, M.; Vesterinen, M.; Vidal, M.; Vilanova, D.; Vilar, R.; Vizán, J.; Vogel, M.; Vokac, P.; Volpi, G.; Wagner, P.; Wahl, H. D.; Wallny, R.; Wang, S. M.; Wang, M. H. L. S.; Wang, R.-J.; Warburton, A.; Warchol, J.; Waters, D.; Watts, G.; Wayne, M.; Weichert, J.; Welty-Rieger, L.; Wester, W. C., III; Whiteson, D.; Wicklund, A. B.; Wilbur, S.; Williams, H. H.; Williams, M. R. J.; Wilson, G. W.; Wilson, J. S.; Wilson, P.; Winer, B. L.; Wittich, P.; Wobisch, M.; Wolbers, S.; Wolfe, H.; Wood, D. R.; Wright, T.; Wu, X.; Wu, Z.; Wyatt, T. R.; Xie, Y.; Yamada, R.; Yamamoto, K.; Yamato, D.; Yang, S.; Yang, T.; Yang, U. K.; Yang, Y. C.; Yao, W.-M.; Yasuda, T.; Yatsunenko, Y. A.; Ye, W.; Ye, Z.; Yeh, G. P.; Yi, K.; Yin, H.; Yip, K.; Yoh, J.; Yorita, K.; Yoshida, T.; Youn, S. W.; Yu, G. B.; Yu, I.; Yu, J. M.; Zanetti, A.; Zeng, Y.; Zennamo, J.; Zhao, T. G.; Zhou, B.; Zhou, C.; Zhu, J.; Zielinski, M.; Zieminska, D.; Zivkovic, L.; Zucchelli, S.

    2013-09-01

    We combine searches by the CDF and D0 Collaborations for the standard model Higgs boson with mass in the range 90-200GeV/c2 produced in the gluon-gluon fusion, WH, ZH, tt¯H, and vector boson fusion processes, and decaying in the H→bb¯, H→W+W-, H→ZZ, H→τ+τ-, and H→γγ modes. The data correspond to integrated luminosities of up to 10fb-1 and were collected at the Fermilab Tevatron in pp¯ collisions at s=1.96TeV. The searches are also interpreted in the context of fermiophobic and fourth generation models. We observe a significant excess of events in the mass range between 115 and 140GeV/c2. The local significance corresponds to 3.0 standard deviations at mH=125GeV/c2, consistent with the mass of the Higgs boson observed at the LHC, and we expect a local significance of 1.9 standard deviations. We separately combine searches for H→bb¯, H→W+W-, H→τ+τ-, and H→γγ. The observed signal strengths in all channels are consistent with the presence of a standard model Higgs boson with a mass of 125GeV/c2.

  17. La chasse au boson de Higgs

    CERN Multimedia

    Grousson, Mathieu

    2007-01-01

    AT the end of 2007, the most powerful particle accelerator in the world will come into force. Protons will collide at the speed of the light. The great hope of searchers: to find in the remains resulting from these shocks, the famous Higgs boson. (6 pages)

  18. Higgs Boson Studies at the Tevatron

    CERN Document Server

    Aaltonen, T.; Abbott, B.; Acharya, B.S.; Adams, M.; Adams, T.; Alexeev, G.D.; Alkhazov, G.; Alton, A.; Amerio, S.; Amidei, D.; Anastassov, A.; Annovi, A.; Antos, J.; Apollinari, G.; Appel, J.A.; Arisawa, T.; Artikov, A.; Asaadi, J.; Ashmanskas, W.; Askew, A.; Atkins, S.; Auerbach, B.; Augsten, K.; Aurisano, A.; Avila, C.; Azfar, F.; Badaud, F.; Badgett, W.; Bae, T.; Bagby, L.; Baldin, B.; Bandurin, D.V.; Banerjee, S.; Barbaro-Galtieri, A.; Barberis, E.; Baringer, P.; Barnes, V.E.; Barnett, B.A.; Barria, P.; Bartlett, J.F.; Bartos, P.; Bassler, U.; Bauce, M.; Bazterra, V.; Bean, A.; Bedeschi, F.; Begalli, M.; Behari, S.; Bellantoni, L.; Bellettini, G.; Bellinger, J.; Benjamin, D.; Beretvas, A.; Beri, S.B.; Bernardi, G.; Bernhard, R.; Bertram, I.; Besancon, M.; Beuselinck, R.; Bhat, P.C.; Bhatia, S.; Bhatnagar, V.; Bhatti, A.; Bland, K.R.; Blazey, G.; Blessing, S.; Bloom, K.; Blumenfeld, B.; Bocci, A.; Bodek, A.; Boehnlein, A.; Boline, D.; Boos, E.E.; Borissov, G.; Bortoletto, D.; Boudreau, J.; Boveia, A.; Brandt, A.; Brandt, O.; Brigliadori, L.; Brock, R.; Bromberg, C.; Bross, A.; Brown, D.; Brucken, E.; Budagov, J.; Bu, X.B.; Budd, H.S.; Buehler, M.; Buescher, V.; Bunichev, V.; Burdin, S.; Burkett, K.; Busetto, G.; Bussey, P.; Buszello, C.P.; Butti, P.; Buzatu, A.; Calamba, A.; Camacho-Perez, E.; Camarda, S.; Campanelli, M.; Canelli, F.; Carls, B.; Carlsmith, D.; Carosi, R.; Carrillo, S.; Casal, B.; Casarsa, M.; Casey, B.C.K.; Castilla-Valdez, H.; Castro, A.; Catastini, P.; Caughron, S.; Cauz, D.; Cavaliere, V.; Cavalli-Sforza, M.; Cerri, A.; Cerrito, L.; Chakrabarti, S.; Chakraborty, D.; Chan, K.M.; Chandra, A.; Chapon, E.; Chen, G.; Chen, Y.C.; Chertok, M.; Chiarelli, G.; Chlachidze, G.; Cho, K.; Cho, S.W.; Choi, S.; Chokheli, D.; Choudhary, B.; Cihangir, S.; Ciocci, M.A.; Claes, D.; Clark, A.; Clarke, C.; Clutter, J.; Convery, M.E.; Conway, J.; Cooke, M.; Cooper, W.E.; Corbo, M.; Corcoran, M.; Cordelli, M.; Couderc, F.; Cousinou, M.C.; Cox, C.A.; Cox, D.J.; Cremonesi, M.; Cruz, D.; Cuevas, J.; Culbertson, R.; Cutts, D.; d'Ascenzo, N.; Das, A.; Datta, M.; Davies, G.; de Barbaro, P.; de Jong, S., J.; De La Cruz-Burelo, E.; Deliot, F.; Demina, R.; Demortier, L.; Deninno, M.; Denisov, D.; Denisov, S.P.; d'Errico, M.; Desai, S.; Deterre, C.; DeVaughan, K.; Devoto, F.; Di Canto, A.; Di Ruzza, B.; Diehl, H.T.; Diesburg, M.; Ding, P.F.; Dittmann, J.R.; Dominguez, A.; Donati, S.; D'Onofrio, M.; Dorigo, M.; Driutti, A.; Dubey, A.; Dudko, L.V.; Duperrin, A.; Dutt, S.; Dyshkant, A.; Eads, M.; Ebina, K.; Edgar, R.; Edmunds, D.; Elagin, A.; Ellison, J.; Elvira, V.D.; Enari, Y.; Erbacher, R.; Errede, S.; Esham, B.; Eusebi, R.; Evans, H.; Evdokimov, V.N.; Facini, G.; Farrington, S.; Faure, A.; Feng, L.; Ferbel, T.; Fernandez Ramos, J.P.; Fiedler, F.; Field, R.; Filthaut, F.; Fisher, W.; Fisk, H.E.; Flanagan, G.; Forrest, R.; Fortner, M.; Fox, H.; Franklin, M.; Freeman, J.C.; Frisch, H.; Fuess, S.; Funakoshi, Y.; Garcia-Bellido, A.; Garcia-Gonzalez, J.A.; Garcia-Guerra, G.A.; Garfinkel, A.F.; Garosi, P.; Gavrilov, V.; Geng, W.; Gerber, C.E.; Gerberich, H.; Gerchtein, E.; Giagu, S.; Giakoumopoulou, V.; Gibson, K.; Ginsburg, C.M.; Ginther, G.; Giokaris, N.; Giromini, P.; Giurgiu, G.; Glagolev, V.; Glenzinski, D.; Gold, M.; Goldin, D.; Golossanov, A.; Golovanov, G.; Gomez, G.; Gomez-Ceballos, G.; Goncharov, M.; Gonzalez Lopez, O.; Gorelov, I.; Goshaw, A.T.; Goulianos, K.; Gramellini, E.; Grannis, P.D.; Greder, S.; Greenlee, H.; Grenier, G.; Grinstein, S.; Gris, Ph.; Grivaz, J.F.; Grohsjean, A.; Grosso-Pilcher, C.; Group, R.C.; Grunendahl, S.; Grunewald, M.W.; Guillemin, T.; Guimaraes da Costa, J.; Gutierrez, G.; Gutierrez, P.; Hahn, S.R.; Haley, J.; Han, J.Y.; Han, L.; Happacher, F.; Hara, K.; Harder, K.; Hare, M.; Harel, A.; Harr, R.F.; Harrington-Taber, T.; Hatakeyama, K.; Hauptman, J.M.; Hays, C.; Hays, J.; Head, T.; Hebbeker, T.; Hedin, D.; Hegab, H.; Heinrich, J.; Heinson, A.P.; Heintz, U.; Hensel, C.; Heredia-De La Cruz, I.; Herndon, M.; Herner, K.; Hesketh, G.; Hildreth, M.D.; Hirosky, R.; Hoang, T.; Hobbs, J.D.; Hocker, A.; Hoeneisen, B.; Hogan, J.; Hohlfeld, M.; Hong, Z.; Hopkins, W.; Hou, S.; Howley, I.; Hubacek, Z.; Hughes, R.E.; Husemann, U.; Hussein, M.; Huston, J.; Hynek, V.; Iashvili, I.; Ilchenko, Y.; Illingworth, R.; Introzzi, G.; Iori, M.; Ito, A.S.; Ivanov, A.; Jabeen, S.; Jaffre, M.; James, E.; Jang, D.; Jayasinghe, A.; Jayatilaka, B.; Jeon, E.J.; Jeong, M.S.; Jesik, R.; Jiang, P.; Jindariani, S.; Johns, K.; Johnson, E.; Johnson, M.; Jonckheere, A.; Jones, M.; Jonsson, P.; Joo, K.K.; Joshi, J.; Jun, S.Y.; Jung, A.W.; Junk, T.R.; Juste, A.; Kajfasz, E.; Kambeitz, M.; Kamon, T.; Karchin, P.E.; Karmanov, D.; Kasmi, A.; Kato, Y.; Katsanos, I.; Kehoe, R.; Kermiche, S.; Ketchum, W.; Keung, J.; Khalatyan, N.; Khanov, A.; Kharchilava, A.; Kharzheev, Y.N.; Kilminster, B.; Kim, D.H.; Kim, H.S.; Kim, J.E.; Kim, M.J.; Kim, S.B.; Kim, S.H.; Kim, Y.J.; Kim, Y.K.; Kimura, N.; Kirby, M.; Kiselevich, I.; Knoepfel, K.; Kohli, J.M.; Kondo, K.; Kong, D.J.; Konigsberg, J.; Kotwal, A.V.; Kozelov, A.V.; Kraus, J.; Kreps, M.; Kroll, J.; Kruse, M.; Kuhr, T.; Kumar, A.; Kupco, A.; Kurata, M.; Kurca, T.; Kuzmin, V.A.; Laasanen, A.T.; Lammel, S.; Lammers, S.; Lancaster, M.; Lannon, K.; Latino, G.; Lebrun, P.; Lee, Hyeon-Seung; Lee, Hyun Su; Lee, J.S.; Lee, S.W.; Lee, W.M.; Lei, X.; Lellouch, J.; Leo, S.; Leone, S.; Lewis, J.D.; Li, D.; Li, D.; Li, H.; Li, L.; Li, Q.Z.; Lim, J.K.; Limosani, A.; Lincoln, D.; Linnemann, J.; Lipaev, V.V.; Lipeles, E.; Lipton, R.; Lister, A.; Liu, H.; Liu, H.; Liu, Q.; Liu, T.; Liu, Y.; Lobodenko, A.; Lockwitz, S.; Loginov, A.; Lokajicek, M.; Lopes de Sa, R.; Lucchesi, D.; Lueck, J.; Lujan, P.; Lukens, P.; Luna-Garcia, R.; Lungu, G.; Lyon, A.L.; Lys, J.; Lysak, R.; Maciel, A.K.A.; Madar, R.; Madrak, R.; Maestro, P.; Magana-Villalba, R.; Malik, S.; Malik, S.; Malyshev, V.L.; Manca, G.; Manousakis-Katsikakis, A.; Mansour, J.; Margaroli, F.; Marino, P.; Martinez, M.; Martinez-Ortega, J.; Matera, K.; Mattson, M.E.; Mazzacane, A.; Mazzanti, P.; McCarthy, R.; McGivern, C.L.; McNulty, R.; Mehta, A.; Mehtala, P.; Meijer, M.M.; Melnitchouk, A.; Menezes, D.; Mercadante, P.G.; Merkin, M.; Mesropian, C.; Meyer, A.; Meyer, J.; Miao, T.; Miconi, F.; Mietlicki, D.; Mitra, A.; Miyake, H.; Moed, S.; Moggi, N.; Mondal, N.K.; Moon, C.S.; Moore, R.; Morello, M.J.; Mukherjee, A.; Mulhearn, M.; Muller, Th.; Murat, P.; Mussini, M.; Nachtman, J.; Nagai, Y.; Naganoma, J.; Nagy, E.; Naimuddin, M.; Nakano, I.; Napier, A.; Narain, M.; Nayyar, R.; Neal, H.A.; Negret, J.P.; Nett, J.; Neu, C.; Neustroev, P.; Nguyen, H.T.; Nigmanov, T.; Nodulman, L.; Noh, S.Y.; Norniella, O.; Nunnemann, T.; Oakes, L.; Oh, S.H.; Oh, Y.D.; Oksuzian, I.; Okusawa, T.; Orava, R.; Orduna, J.; Ortolan, L.; Osman, N.; Osta, J.; Padilla, M.; Pagliarone, C.; Pal, A.; Palencia, E.; Palni, P.; Papadimitriou, V.; Parashar, N.; Parihar, V.; Park, S.K.; Parker, W.; Partridge, R.; Parua, N.; Patwa, A.; Pauletta, G.; Paulini, M.; Paus, C.; Penning, B.; Perfilov, M.; Peters, Y.; Petridis, K.; Petrillo, G.; Petroff, P.; Phillips, T.J.; Piacentino, G.; Pianori, E.; Pilot, J.; Pitts, K.; Plager, C.; Pleier, M.A.; Podesta-Lerma, P.L.M.; Podstavkov, V.M.; Pondrom, L.; Popov, A.V.; Poprocki, S.; Potamianos, K.; Pranko, A.; Prewitt, M.; Price, D.; Prokopenko, N.; Prokoshin, F.; Ptohos, F.; Punzi, G.; Qian, J.; Quadt, A.; Quinn, B.; Rangel, M.S.; Ranjan, N.; Ratoff, P.N.; Razumov, I.; Redondo Fernandez, I.; Renton, P.; Rescigno, M.; Rimondi, F.; Ripp-Baudot, I.; Ristori, L.; Rizatdinova, F.; Robson, A.; Rodriguez, T.; Rolli, S.; Rominsky, M.; Ronzani, M.; Roser, R.; Rosner, J.L.; Ross, A.; Royon, C.; Rubinov, P.; Ruchti, R.; Ruffini, F.; Ruiz, A.; Russ, J.; Rusu, V.; Sajot, G.; Sakumoto, W.K.; Sakurai, Y.; Salcido, P.; Sanchez-Hernandez, A.; Sanders, M.P.; Santi, L.; Santos, A.S.; Sato, K.; Savage, G.; Saveliev, V.; Savoy-Navarro, A.; Sawyer, L.; Scanlon, T.; Schamberger, R.D.; Scheglov, Y.; Schellman, H.; Schlabach, P.; Schmidt, E.E.; Schwanenberger, C.; Schwarz, T.; Schwienhorst, R.; Scodellaro, L.; Scuri, F.; Seidel, S.; Seiya, Y.; Sekaric, J.; Semenov, A.; Severini, H.; Sforza, F.; Shabalina, E.; Shalhout, S.Z.; Shary, V.; Shaw, S.; Shchukin, A.A.; Shears, T.; Shepard, P.F.; Shimojima, M.; Shivpuri, R.K.; Shochet, M.; Shreyber-Tecker, I.; Simak, V.; Simonenko, A.; Sinervo, P.; Skubic, P.; Slattery, P.; Sliwa, K.; Smirnov, D.; Smith, J.R.; Smith, K.J.; Snider, F.D.; Snow, G.R.; Snow, J.; Snyder, S.; Soldner-Rembold, S.; Song, H.; Sonnenschein, L.; Sorin, V.; Soustruznik, K.; Stancari, M.; St. Denis, R.; Stark, J.; Stelzer, B.; Stelzer-Chilton, O.; Stentz, D.; Stoyanova, D.A.; Strauss, M.; Strologas, J.; Sudo, Y.; Sukhanov, A.; Suslov, I.; Suter, L.; Svoisky, P.; Takemasa, K.; Takeuchi, Y.; Tang, J.; Tecchio, M.; Teng, P.K.; Thom, J.; Thomson, E.; Thukral, V.; Titov, M.; Toback, D.; Tokar, S.; Tokmenin, V.V.; Tollefson, K.; Tomura, T.; Tonelli, D.; Torre, S.; Torretta, D.; Totaro, P.; Trovato, M.; Tsai, Y.T.; Tsybychev, D.; Tuchming, B.; Tully, C.; Ukegawa, F.; Uozumi, S.; Uvarov, L.; Uvarov, S.; Uzunyan, S.; Van Kooten, R.; Van Leeuwen, W.M.; Varelas, N.; Varnes, E.W.; Vasilyev, I.A.; Vazquez, F.; Velev, G.; Vellidis, C.; Verkheev, A.Y.; Vernieri, C.; Vertogradov, L.S.; Verzocchi, M.; Vesterinen, M.; Vidal, M.; Vilanova, D.; Vilar, R.; Vizan, J.; Vogel, M.; Vokac, P.; Volpi, G.; Wagner, P.; Wahl, H.D.; Wallny, R.; Wang, S.M.; Wang, M.H.L.S.; Wang, R.J.; Warburton, A.; Warchol, J.; Waters, D.; Watts, G.; Wayne, M.; Weichert, J.; Welty-Rieger, L.; Wester, W.C., III; White, A.; Whiteson, D.; Wicke, D.; Wicklund, A.B.; Wilbur, S.; Williams, H.H.; Williams, M.R.J.; Wilson, G.W.; Wilson, J.S.; Wilson, P.; Winer, B.L.; Wittich, P.; Wobisch, M.; Wolbers, S.; Wolfe, H.; Wood, D.R.; Wright, T.; Wu, X.; Wu, Z.; Wyatt, T.R.; Xie, Y.; Yamada, R.; Yamamoto, K.; Yamato, D.; Yang, S.; Yang, T.; Yang, U.K.; Yang, Y.C.; Yao, W.M.; Yasuda, T.; Yatsunenko, Y.A.; Ye, W.; Ye, Z.; Yeh, G.P.; Yi, K.; Yin, H.; Yip, K.; Yoh, J.; Yorita, K.; Yoshida, T.; Youn, S.W.; Yu, G.B.; Yu, I.; Yu, J.M.; Zanetti, A.; Zeng, Y.; Zennamo, J.; Zhao, T.G.; Zhou, B.; Zhou, C.; Zhu, J.; Zielinski, M.; Zieminska, D.; Zivkovic, L.; Zucchelli, S.

    2013-01-01

    We combine searches by the CDF and D0 Collaborations for the standard model Higgs boson with mass in the range 90--200 GeV/c^2 produced in the gluon-gluon fusion, WH, ZH, ttbarH, and vector boson fusion processes, and decaying in the H->bbbar, H->W^+W^-, H->ZZ, H->\\tau^+\\tau^-, and H->\\gamma \\gamma\\ modes. The data correspond to integrated luminosities of up to 10 fb^-1 and were collected at the Fermilab Tevatron in ppbar collisions at sqrt(s)=1.96 TeV. The searches are also interpreted in the context of fermiophobic and fourth generation models. We observe a significant excess of events in the mass range between 115 and 140 GeV/c^2. The local significance corresponds to 3.1 standard deviations at m_H=125 GeV/c^2, consistent with the mass of the Higgs boson observed at the LHC. Furthermore, we separately combine searches for H->bbbar, H->W^+W^-, H->\\tau^+\\tau^-, and H->\\gamma \\gamma. The observed signal strengths in all channels are consistent with the presence of a standard model Higgs boson with a mass of 1...

  19. Bosons & More: Celebrating CERN / Part 2

    CERN Multimedia

    Team, CERN

    2013-01-01

    The "Bosons & More" event for CERN people this evening celebrated the success of the Open Days, and the exceptional achievements of the Large Hadron Collider (LHC). The British progressive rock band the Alan Parsons Live Project lead the celebrations until late in the night.

  20. Universality in bosonic dimer-dimer scattering

    Energy Technology Data Exchange (ETDEWEB)

    Deltuva, A. [Centro de Fisica Nuclear, Universidade de Lisboa, P-1649-003 Lisboa (Portugal)

    2011-08-15

    Bosonic dimer-dimer scattering is studied near the unitary limit using momentum-space equations for the four-particle transition operators. The impact of the Efimov effect on the dimer-dimer scattering observables is explored, and a number of universal relations is established with high accuracy. The rate for the creation of Efimov trimers via dimer-dimer collisions is calculated.

  1. Combinatorial Solutions to Normal Ordering of Bosons

    CERN Document Server

    Blasiak, P; Horzela, A; Penson, K A; Solomon, A I

    2005-01-01

    We present a combinatorial method of constructing solutions to the normal ordering of boson operators. Generalizations of standard combinatorial notions - the Stirling and Bell numbers, Bell polynomials and Dobinski relations - lead to calculational tools which allow to find explicitly normally ordered forms for a large class of operator functions.

  2. Single Boson Realizations of the Higgs Algebra

    Institute of Scientific and Technical Information of China (English)

    RUANDong; WUChu; SUNHong-Zhou

    2003-01-01

    We obtained for the Higgs algebra three kinds of single boson realizations such as the unitary Holstein-Primakoff-like realization, the non-unitary Dyson-like realization, and the unitary Villain-like realization. The corre-sponding similarity transformations between the Holstein-Primakoff-like realizations and the Dyson-like realizations are given.

  3. Trapping fermionic and bosonic helium atoms

    NARCIS (Netherlands)

    Stas, R.J.W.

    2005-01-01

    This thesis presents experimental and theoretical work performed at the Laser Centre of the Vrije Universiteit in Amsterdam to study laser-cooled metastable triplet helium atoms. Samples containing about 3x10^8 helium atoms-either fermionic helium-3 atoms, bosonic helium-4 atoms or mixtures thereof

  4. Parameter Symmetry of the Interacting Boson Model

    CERN Document Server

    Shirokov, A M; Smirnov, Yu F; Shirokov, Andrey M.; Smirnov, Yu. F.

    1998-01-01

    We discuss the symmetry of the parameter space of the interacting boson model (IBM). It is shown that for any set of the IBM Hamiltonian parameters (with the only exception of the U(5) dynamical symmetry limit) one can always find another set that generates the equivalent spectrum. We discuss the origin of the symmetry and its relevance for physical applications.

  5. Electroweak Chiral Lagrangian for Neutral Higgs Boson

    Institute of Scientific and Technical Information of China (English)

    WANG Shun-Zhi; WANG Qing

    2008-01-01

    A neutral Higgs boson is added into the traditional electroweak chiral Lagrangian by writing down all possible high dimension operators. The matter part of the Lagrangian is investigated in detail. We find that if Higgs field dependence of Yukawa couplings can be factorized out, there will be no flavour changing neutral couplings; neutral Higgs can induce coupling between light and heavy neutrinos.

  6. The LIPSS search for light neutral bosons

    Energy Technology Data Exchange (ETDEWEB)

    Andrei Afanasev; Oliver K. Baker; Kevin Beard; George Biallas; James Boyce; Minarni Minarni; Roopchan Ramdon; Michelle D. Shinn; Penny Slocum

    2009-07-01

    An overview is presented of the LIPSS experimental search for very light neutral bosons using laser light from Jefferson Lab's Free Electron Laser. This facility provides very high power beams of photons over a large optical range, particularly at infrared wavelengths. Data has been collected in several experimental runs during the course of the past three years, most recently in the Fall of 2009.

  7. Probing a composite spin-boson environment

    Energy Technology Data Exchange (ETDEWEB)

    Oxtoby, Neil P; Rivas, Angel; Huelga, Susana F [Quantum Physics Group, STRI, School of Physics, Astronomy and Mathematics, University of Hertfordshire, Hatfield, Herts AL10 9AB (United Kingdom); Fazio, Rosario [NEST CNR-INFM and Scuola Normale Superiore, Piazza dei Cavalieri 7, I-56126 Pisa (Italy)], E-mail: s.f.huelga@herts.ac.uk

    2009-06-15

    We consider non-interacting multi-qubit systems as controllable probes of an environment of defects/impurities modelled as a composite spin-boson environment. The spin-boson environment consists of a small number of quantum-coherent two-level fluctuators (TLFs) damped by independent bosonic baths. A master equation of the Lindblad form is derived for the probe-plus-TLF system. We discuss how correlation measurements in the probe system encode information about the environment structure and could be exploited to efficiently discriminate between different experimental preparation techniques, with particular focus on the quantum correlations (entanglement) that build up in the probe as a result of the TLF-mediated interaction. We also investigate the harmful effects of the composite spin-boson environment on initially prepared entangled bipartite qubit states of the probe and on entangling gate operations. Our results offer insights in the area of quantum computation using superconducting devices, where defects/impurities are believed to be a major source of decoherence.

  8. Boson Stars in Higher Derivative Gravity

    CERN Document Server

    Baibhav, Vishal

    2016-01-01

    In this paper, we have constructed Boson star (BS) solutions in four dimensional scalar-Gauss-Bonnet (sGB) theory. In order to have non-trivial effect from Gauss-Bonnet term, we invoked non-minimal coupling between a complex scalar field and the Gauss-Bonnet term with a coupling parameter, $\\alpha$. We show that the scalar field can no longer take arbitrary value at the center of the star. Furthermore, boson-stars in our higher derivative theory turn out to be slightly massive but much more compact than those in the usual Einstein's gravity. Interestingly, we found that for $\\alpha0.8$, binding energy for all possible boson stars is always negative. This implies that these stars are intrinsically stable against the decay by dispersion. We also present the mass-radius and mass-frequency curves for boson-star and compare them with other compact objects in gravity models derived from Gauss-Bonnet term.

  9. Boson stars in higher-derivative gravity

    Science.gov (United States)

    Baibhav, Vishal; Maity, Debaprasad

    2017-01-01

    In this paper, we have constructed boson star (BS) solutions in four-dimensional scalar-Gauss-Bonnet (sGB) theory. In order to have a nontrivial effect from the Gauss-Bonnet term, we invoked nonminimal coupling between a complex scalar field and the Gauss-Bonnet term with a coupling parameter, α . We show that the scalar field can no longer take arbitrary value at the center of the star. Furthermore, boson stars in our higher-derivative theory turn out to be slightly massive but much more compact than those in the usual Einstein's gravity. Interestingly, we found that for α 0.8 , binding energy for all possible boson stars is always negative. This implies that these stars are intrinsically stable against the decay by dispersion. However, for -0.4 negative binding energy depending on scalar field value at the center of the star. We also present the mass-radius and mass-frequency curves for boson stars and compare them with other compact objects in gravity models derived from the Gauss-Bonnet term.

  10. The search for the Higgs boson

    CERN Multimedia

    Riordan, M; Wu Sau Lan

    2001-01-01

    A critical requirement of the Standard Model is a mechanism to endow elementary particles with mass. This mechanism should manifest itself as the Higgs boson and a number of accelerator laboratories are designing machines and experiments to find it (1 1/2 pages).

  11. Higgs boson physics at the LHC

    CERN Document Server

    Ocariz, Jose; The ATLAS collaboration

    2016-01-01

    The experimental status on Higgs boson physics is reviewed. Results from both ATLAS and CMS, using data collected in LHC run 1, are presented. First preliminary results from data collected in 2015 at 13 TeV are also presented. Prospects for Higgs physics with Run 2 and beyond are discussed.

  12. Bosonic physical states in N = 1 supergravity?

    CERN Document Server

    Carroll, S M; Ortiz, M E; Page, D N; Carroll, S M; Freedman, D Z; Ortiz, M E; Page, D N

    1994-01-01

    It is argued that states in N=1 supergravity that solve all of the constraint equations cannot be bosonic in the sense of being independent of the fermionic degrees of freedom. (Based on a talk given by Miguel Ortiz at the 7th Marcel Grossmann Meeting.)

  13. Accelerating research into the Higgs boson particle

    CERN Multimedia

    Nikolaidou, Rosy

    "The only Standard Model particle yet to be observed, the search for the Higgs Boson - the so-called 'God Particle' - demands advanced facilities and physics expertise. At the Cern laboratory in Switzerland, the ARTEMIS project is well-placed to pursue research in this area" (2 pages)

  14. Interaction between bosonic dark matter and stars

    CERN Document Server

    Brito, Richard; Macedo, Caio F B; Okawa, Hirotada; Palenzuela, Carlos

    2015-01-01

    We provide a detailed analysis of how bosonic dark matter "condensates" interact with compact stars, extending significantly the results of a recent Letter. We focus on bosonic fields with mass $m_B$, such as axions, axion-like candidates and hidden photons. Self-gravitating bosonic fields generically form "breathing" configurations, where both the spacetime geometry and the field oscillate, and can interact and cluster at the center of stars. We construct stellar configurations formed by a perfect fluid and a bosonic condensate, and which may describe the late stages of dark-matter accretion onto stars, in dark matter-rich environments. These composite stars oscillate at a frequency which is a multiple of $f=2.5\\times 10^{14}\\,\\left(m_{B}c^2/eV\\right)\\,{\\rm Hz}$. Using perturbative analysis and Numerical Relativity techniques, we show that these stars are generically stable, and we provide criteria for instability. Our results also indicate that the growth of the dark matter core is halted close to the Chand...

  15. Comparison of associated Higgs boson-radion and Higgs boson pair production processes

    Science.gov (United States)

    Boos, E.; Keizerov, S.; Rakhmetov, E.; Svirina, K.

    2016-07-01

    Many models—in particular, the brane-world models with two branes—predict the existence of the scalar radion, whose mass can be somewhat smaller than those of all the Kaluza-Klein modes of the graviton and Standard Model (SM) particles. Due to its origin the radion interacts with the trace of the energy-momentum tensor of the SM. The fermion part of the radion interaction Lagrangian is different from that for the SM Higgs boson due to the presence of additional terms playing a role for off-shell fermions. It was shown previously [Phys. Rev. D 90, 095026 (2014), 10.1103/PhysRevD.90.095026] that for the case of the single radion and single Higgs boson production processes in association with an arbitrary number of SM gauge bosons all the contributions to the perturbative amplitudes appearing due to these additional terms were canceled out, making the processes similar up to a replacement of masses and overall coupling constants. For the case of the associated Higgs boson-radion and the Higgs boson pair-production processes involving the SM gauge bosons, the similarity property also appears. However, a detailed consideration shows that in this case it is not enough to simply replace the masses and the constants (mh→mr and v →Λr). One should also rescale the triple Higgs coupling by the factor ξ ≡1 +m/r2-mh2 3 mh2 .

  16. Higher order corrections to Higgs boson decays in the MSSM with complex parameters

    Energy Technology Data Exchange (ETDEWEB)

    Williams, Karina E. [Bonn Univ. (Germany). Bethe Center for Theoretical Physics; Rzehak, Heidi [Freiburg Univ. (Germany). Physikalisches Inst.; Weiglein, Georg [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany)

    2011-03-15

    We discuss Higgs boson decays in the CP-violating MSSM, and examine their phe- nomenological impact using cross section limits from the LEP Higgs searches. This includes a discussion of the full 1-loop results for the partial decay widths of neutral Higgs bosons into lighter neutral Higgs bosons (h{sub a}{yields}h{sub b}h{sub c}) and of neutral Higgs bosons into fermions (h{sub a}{yields}f anti f). In calculating the genuine vertex corrections, we take into account the full spectrum of supersymmetric particles and all complex phases of the supersymmetric parameters. These genuine vertex corrections are supplemented with Higgs propagator corrections incorporating the full one-loop and the dominant two-loop contributions, and we illustrate a method of consistently treating diagrams involving mixing with Goldstone and Z bosons. In particular, the genuine vertex corrections to the process h{sub a}{yields}h{sub b}h{sub c} are found to be very large and, where this process is kinematically allowed, can have a significant effect on the regions of the CPX bench- mark scenario which can be excluded by the results of the Higgs searches at LEP. However, there remains an unexcluded region of CPX parameter space at a lightest neutral Higgs boson mass of {proportional_to}45 GeV. In the analysis, we pay particular attention to the conversion between parameters defined in different renormalisation schemes and are therefore able to make a comparison to the results found using renormalisation group improved/effective potential calculations. (orig.)

  17. Search for new heavy charged gauge bosons

    Energy Technology Data Exchange (ETDEWEB)

    Magass, Carsten Martin

    2007-11-02

    The TEVATRON proton-antiproton collider at FERMILAB (near Chicago/USA) is operating at a center-of-mass energy of {radical}(s)=1.96 TeV since March 2001. This analysis uses data taken with the DOe detector until February 2006 corresponding to an integrated luminosity of about {integral}Ldt=1 fb{sup -1}. Using this dataset, a search for a new heavy charged gauge boson W{sup '} and its subsequent decay into an electron and a neutrino is performed: p anti p{yields}W{sup '}+X{yields}e{nu}+X. Additional gauge bosons (including the equivalent to the Z, the Z{sup '}) are introduced in many extensions to the Standard Model of particle physics. Assuming the most general case, the new gauge group can comprise a new mixing angle and new couplings. Here, the Altarelli Reference Model is considered which represents a generalization of the Manifest Left-Right Symmetric Model with light right-handed neutrinos. This model makes the assumptions that the new gauge boson W{sup '} has the same couplings as the Standard Model W boson and that there is no mixing. Hence, the W{sup '} is a heavy copy of the Standard Model W boson. The clear decay signature (in analogy to the decay of the W) contains an isolated electron with extreme high energy which is important for triggering. The neutrino can not be detected, but it gives rise to missing energy in the detector. The Jacobian peak in the transverse mass distribution stemming from the W decay is used for calibration, whereas the tail of the transverse mass distribution is searched for a possible W{sup '} signal. The data agrees with the expectation from background processes. For instance, in the data 37 events are reconstructed with transverse masses above 300 GeV compared to a prediction of 37.1{+-}2.1(stat){sup +6.0}{sub -3.7}(sys) background events. Since no significant excess is found in the data, an upper limit is set on the production cross section for heavy charged gauge bosons decaying into electron

  18. The CMS electromagnetic calorimeter and the search for the Higgs boson in the decay channel H {yields} WW{sup *} {yields} 2e2{nu}; Le calorimetre electromagnetique de CMS et la recherche du boson de Higgs dans le canal de desintegration H {yields} WW{sup *} {yields} 2e2{nu}

    Energy Technology Data Exchange (ETDEWEB)

    Rovelli, I.Ch

    2006-01-15

    CMS is one of the four experiments that will take data at the LHC. Large part of my work was devoted to the development of electron reconstruction tools aimed at improving the Higgs boson discovery potential in the H {yields} WW{sup *} {yields} 2e2{nu} channel. A major role in the electron reconstruction is played by the electromagnetic calorimeter ECAL, an homogeneous calorimeter made of scintillating PbWO{sub 4} crystals. The first 3 chapters give an overview of LHC and CMS.In chapter 4 the analysis of the data collected during the 2003 electromagnetic calorimeter test beam is presented. First the problem of the intercalibration at the test beam is addressed. This is a major task, since the precision of the intercalibration directly affects the constant term of the energy resolution, for which the CMS goal is to reach a precision better than 0.5%. The good initial intercalibration, anyway, could be spoiled during the data taking by the effects of the radiation on the crystals, which can change the relative responses of the channels. A monitoring laser system is foreseen at CMS. The possibility to check the calibration stability and to correct the changes in the response with a precision within the required limits is demonstrated. Chapter five describes the electron reconstruction and identification in CMS. A crucial problem for the electron reconstruction is represented by the Bremsstrahlung emission in the tracker. A tracking procedure dealing with the Bremsstrahlung energy loss is discussed. Together with an improvement in the reconstruction efficiency, the procedure allows to identify electrons with a small fraction of radiated energy, which can be usefully exploited for the ECAL calibration. The developed algorithms are applied in chapter 6, which presents the study of the CMS discovery potential of the Higgs boson in the H {yields} WW{sup *} {yields} 2e2{nu} channel. This is the discovery channel in the range of masses between 2m{sub W} and 2m{sub Z}. Here

  19. Discovery of the Potential Role of Sensors in a Personal Emergency Response System: What Can We Learn from a Single Workshop?

    Directory of Open Access Journals (Sweden)

    Femke De Backere

    2015-12-01

    Full Text Available Capturing knowledge from domain experts is important to effectively integrate novel technological support in existing care processes. In this paper, we present our experiences in using a specific type of workshop, which we identified as a decision-tree workshop, to determine the process and information exchange during the usage of a Personal Emergency Response System (PERS. We conducted the workshop with current and possible future users of a PERS system to investigate the potential of context- and social awareness for such a system. We discuss the workshop format as well as the results and reflection on this workshop.

  20. Population genetic structure of Phytophthora cinnamomi associated with avocado in California and the discovery of a potentially recent introduction of a new clonal lineage.

    Science.gov (United States)

    Pagliaccia, D; Pond, E; McKee, B; Douhan, G W

    2013-01-01

    Phytophthora root rot (PRR) of avocado (Persea americana), caused by Phytophthora cinnamomi, is the most serious disease of avocado worldwide. Previous studies have determined that this pathogen exhibits a primarily clonal reproductive mode but no population level studies have been conducted in the avocado-growing regions of California. Therefore, we used amplified fragment length polymorphism based on 22 polymorphic loci and mating type to investigate pathogen diversity from 138 isolates collected in 2009 to 2010 from 15 groves from the Northern and Southern avocado-growing regions. Additional isolates collected from avocado from 1966 to 2007 as well as isolates from other countries and hosts were also used for comparative purposes. Two distinct clades of A2 mating-type isolates from avocado were found based on neighbor joining analysis; one clade contained both newer and older collections from Northern and Southern California, whereas the other clade only contained isolates collected in 2009 and 2010 from Southern California. A third clade was also found that only contained A1 isolates from various hosts. Within the California population, a total of 16 genotypes were found with only one to four genotypes identified from any one location. The results indicate significant population structure in the California avocado P. cinnamomi population, low genotypic diversity consistent with asexual reproduction, potential evidence for the movement of clonal genotypes between the two growing regions, and a potential introduction of a new clonal lineage into Southern California.