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Sample records for bohrium 274

  1. 7 CFR 274.7 - Coupon management.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Coupon management. 274.7 Section 274.7 Agriculture... FOOD STAMP AND FOOD DISTRIBUTION PROGRAM ISSUANCE AND USE OF COUPONS § 274.7 Coupon management. (a) Coupon inventory management. State agencies shall establish coupon inventory management systems...

  2. 7 CFR 274.3 - Issuance systems.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Issuance systems. 274.3 Section 274.3 Agriculture... FOOD STAMP AND FOOD DISTRIBUTION PROGRAM ISSUANCE AND USE OF COUPONS § 274.3 Issuance systems. (a) System classification. State agencies may issue benefits to households through any of the following...

  3. 33 CFR 274.5 - Certification.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Certification. 274.5 Section 274... PEST CONTROL PROGRAM FOR CIVIL WORKS PROJECTS Project Operation § 274.5 Certification. Under the... certification of pesticide applicators through its development of a single Government Agency Plan (GAP)....

  4. 33 CFR 274.4 - Pesticide management.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Pesticide management. 274.4... DEFENSE PEST CONTROL PROGRAM FOR CIVIL WORKS PROJECTS Project Operation § 274.4 Pesticide management. (a... control management personnel prior to advertisement of the contract and procurement of services....

  5. 38 CFR 17.274 - Cost sharing.

    Science.gov (United States)

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2010-07-01 2010-07-01 false Cost sharing. 17.274 Section 17.274 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS MEDICAL Civilian... the beneficiary cost share. (b) In addition to the beneficiary cost share, an annual (calendar...

  6. Dicty_cDB: CHR274 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available CH (Link to library) CHR274 (Link to dictyBase) - G23014 DDB0205932 Contig-U11587-1 | Contig-U13150-1 CHR...274P (Link to Original site) CHR274F 618 CHR274Z 715 CHR274P 1313 - - Show CHR274 Libr...ary CH (Link to library) Clone ID CHR274 (Link to dictyBase) Atlas ID - NBRP ID G23014 dictyBase ID DDB02059...ycdb.biol.tsukuba.ac.jp/CSM/CH/CHR2-D/CHR274Q.Seq.d/ Representative seq. ID CHR274P (Link to Original site) ...Representative DNA sequence >CHR274 (CHR274Q) /CSM/CH/CHR2-D/CHR274Q.Seq.d/ GTAATAATAATTTTAAAAAATCAAATAGTAAT

  7. Dicty_cDB: SSG274 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available SS (Link to library) SSG274 (Link to dictyBase) - G01218 DDB0190845 Contig-U11005-1 SSG...274P (Link to Original site) SSG274F 390 SSG274Z 515 SSG274P 905 - - Show SSG274 Library SS (Link to library) Clone ID SSG...ontig-U11005-1 Original site URL http://dictycdb.biol.tsukuba.ac.jp/CSM/SS/SSG2-D/SSG...274Q.Seq.d/ Representative seq. ID SSG274P (Link to Original site) Representative DNA sequence >SSG274 (SSG274Q) /CSM/SS/SSG...2-D/SSG274Q.Seq.d/ AAATAATAATAATAATAATAATATTGAAAATAATAAAAATAATAAAAATAATAATATTTA ATAATAAA

  8. Dicty_cDB: SLE274 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available ar 16.0 %: mitochondrial 8.0 %: vesicles of secretory system 4.0 %: vacuolar >> prediction for SLE...SL (Link to library) SLE274 (Link to dictyBase) - - - Contig-U12305-1 SLE274P (Link to Original site) SLE...274F 703 SLE274Z 333 SLE274P 1036 - - Show SLE274 Library SL (Link to library) Clone ID SLE...e URL http://dictycdb.biol.tsukuba.ac.jp/CSM/SL/SLE2-D/SLE274Q.Seq.d/ Representative seq. ID SLE...274P (Link to Original site) Representative DNA sequence >SLE274 (SLE274Q) /CSM/SL/SLE2-D/SLE

  9. 27 CFR 25.274 - Bond.

    Science.gov (United States)

    2010-04-01

    ... TREASURY LIQUORS BEER Pilot Brewing Plants § 25.274 Bond. (a) Requirement. Any person requesting authorization to establish a pilot brewing plant under this subpart shall execute and file a brewer's bond, Form... beer brewed, produced, or received on the premises. (Sec. 4, Pub. L. 91-673, 84 Stat. 2057, as amended...

  10. 8 CFR 274a.3 - Continuing employment of unauthorized aliens.

    Science.gov (United States)

    2010-01-01

    ... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Continuing employment of unauthorized aliens. 274a.3 Section 274a.3 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS CONTROL OF EMPLOYMENT OF ALIENS Employer Requirements § 274a.3 Continuing employment of...

  11. 12 CFR 27.4 - Inquiry/Application Log.

    Science.gov (United States)

    2010-01-01

    ... of the Federal Reserve Board, 12 CFR part 203) indicates a pattern of significant variation in the... 12 Banks and Banking 1 2010-01-01 2010-01-01 false Inquiry/Application Log. 27.4 Section 27.4... SYSTEM § 27.4 Inquiry/Application Log. (a) The Comptroller, among other things, may require a bank...

  12. 8 CFR 274.1 - Seizure and forfeiture authority.

    Science.gov (United States)

    2010-01-01

    ... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Seizure and forfeiture authority. 274.1 Section 274.1 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS SEIZURE AND FORFEITURE OF CONVEYANCES § 274.1 Seizure and forfeiture authority. Any officer of Customs and Border...

  13. Properties of an $\\alpha$ particle in a Bohrium $270$ Nucleus under the Generalized Symmetric Woods-Saxon Potential

    CERN Document Server

    Lütfüoğlu, B C

    2016-01-01

    The energy eigenvalues and the wave functions of an $\\alpha$ particle in a Bohrium $270$ nucleus were calculated by solving Schr\\"odinger equation for Generalized Symmetric Woods-Saxon potential. Using the energy spectrum by excluding and including the quasi-bound eigenvalues, entropy, internal energy, Helmholtz energy, and specific heat, as functions of reduced temperature were calculated. Stability and emission characteristics are interpreted in terms of the wave and thermodynamic functions. The kinetic energy of a decayed $\\alpha$ particle was calculated using the quasi-bound states, which is found close to the experimental value.

  14. Properties of an α Particle in a Bohrium 270 Nucleus under the Generalized Symmetric Woods-Saxon Potential

    Directory of Open Access Journals (Sweden)

    Bekir Can LÜTFÜOĞLU

    2017-04-01

    Full Text Available The energy eigenvalues and the wave functions of an α particle in a Bohrium 270 nucleus have been calculated by solving Schrödinger equation for Generalized Symmetric Woods-Saxon potential. Using the energy spectrum by excluding and including the quasi-bound eigenvalues, entropy, internal energy, Helmholtz energy, and specific heat, as functions of reduced temperature have been calculated. Stability and emission characteristics have been interpreted in terms of the wave and thermodynamic functions. The kinetic energy of a decayed α particle was calculated using the quasi-bound states, which has been found close to the experimental value.

  15. 40 CFR 264.274-264.275 - [Reserved

    Science.gov (United States)

    2010-07-01

    ....275 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) STANDARDS FOR OWNERS AND OPERATORS OF HAZARDOUS WASTE TREATMENT, STORAGE, AND DISPOSAL FACILITIES Land Treatment §§ 264.274-264.275 ...

  16. Test report - 241-AN-274 Caustic Pump Control Building

    Energy Technology Data Exchange (ETDEWEB)

    Paintner, G.P.

    1995-05-01

    This Acceptance Test Report documents the test results of test procedure WHC-SD-WM-ATP-135 `Acceptance Test Procedure for the 241-AN- 274 Caustic Pump Control Building.` The objective of the test was to verify that the 241-AN-274 Caustic Pump Control Building functions properly based on design specifications per applicable H-2-85573 drawings and associated ECN`s. The objective of the test was met.

  17. Atomic Mass and Nuclear Binding Energy for Po-274 (Polonium)

    Science.gov (United States)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Po-274 (Polonium, atomic number Z = 84, mass number A = 274).

  18. 26 CFR 1.274-5A - Substantiation requirements.

    Science.gov (United States)

    2010-04-01

    ... substantiated a particular element of an expenditure, but the taxpayer establishes to the satisfaction of the.... If a taxpayer fails to establish to the satisfaction of the district director that he has... food and beverages for employees, section 274(e)(3) relating to expenses treated as...

  19. 40 CFR 761.274 - Reporting PCB concentrations in samples.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Reporting PCB concentrations in... COMMERCE, AND USE PROHIBITIONS Cleanup Site Characterization Sampling for PCB Remediation Waste in Accordance with § 761.61(a)(2) § 761.274 Reporting PCB concentrations in samples. (a) Report all...

  20. 8 CFR 274a.12 - Classes of aliens authorized to accept employment.

    Science.gov (United States)

    2010-01-01

    ... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Classes of aliens authorized to accept employment. 274a.12 Section 274a.12 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS CONTROL OF EMPLOYMENT OF ALIENS Employment Authorization § 274a.12 Classes of aliens authorized to...

  1. 48 CFR 236.274 - Restriction on acquisition of steel for use in military construction projects.

    Science.gov (United States)

    2010-10-01

    ... of steel for use in military construction projects. 236.274 Section 236.274 Federal Acquisition....274 Restriction on acquisition of steel for use in military construction projects. In accordance with..., Division E), do not acquire, or allow a contractor to acquire, steel for any construction project...

  2. The skills for genesis2000 reading 274D%浅谈Genesis读取274D格式技巧

    Institute of Scientific and Technical Information of China (English)

    王忱; 李加余; 黄慧

    2014-01-01

    Genesis 2000是处理PCB线路图形达到现场生产能力并满足客户要求的一种高级计算机辅助制造软件,CAM制作料号前必须将客户提供之CAD/CAM档案转换成厂内可使用之文件格式。 Genesis 2000读取客户资料的正确性,直接会影响每款产品的正确性,文章主要探讨genesis2000读取274D格式技巧。%Genesis 2000 is an advanced computer-aided manufacturing software processing PCB line and graph to reach the production capacity and meet customer requirements. Before the materials process, CAD/CAMfiles must be provided and changed into a plant suitable format which can be used. The correctness of the Genesis 2000 reading customer data directly affects the accuracy of each product. So this paper mainly discusses genesis2000 reading skills of 274D.

  3. 38 CFR 3.274 - Relationship of net worth to pension entitlement.

    Science.gov (United States)

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2010-07-01 2010-07-01 false Relationship of net worth to pension entitlement. 3.274 Section 3.274 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS ADJUDICATION Pension, Compensation, and Dependency and Indemnity Compensation Regulations...

  4. 40 CFR 421.274 - Standards of performance for new sources.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 28 2010-07-01 2010-07-01 true Standards of performance for new sources. 421.274 Section 421.274 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS NONFERROUS METALS MANUFACTURING POINT SOURCE CATEGORY Primary Rare...

  5. Cardiac channelopathy testing in 274 ethnically diverse sudden unexplained deaths.

    Science.gov (United States)

    Wang, Dawei; Shah, Krunal R; Um, Sung Yon; Eng, Lucy S; Zhou, Bo; Lin, Ying; Mitchell, Adele A; Nicaj, Leze; Prinz, Mechthild; McDonald, Thomas V; Sampson, Barbara A; Tang, Yingying

    2014-04-01

    Sudden unexplained deaths (SUD) in apparently healthy individuals, for which the causes of deaths remained undetermined after comprehensive forensic investigations and autopsy, present vexing challenges to medical examiners and coroners. Cardiac channelopathies, a group of inheritable diseases that primarily affect heart rhythm by altering the cardiac conduction system, have been known as one of the likely causes of SUD. Adhering to the recommendations of including molecular diagnostics of cardiac channelopathies in SUD investigation, the Molecular Genetics Laboratory of the New York City (NYC) Office of Chief Medical Examiner (OCME) has been routinely testing for six major channelopathy genes (KCNQ1, KCNH2, SCN5A, KCNE1, KCNE2, and RyR2) since 2008. Presented here are the results of cardiac channelopathy testing in 274 well-characterized autopsy negative SUD cases, all with thorough medicolegal death investigation including complete autopsy by NYC OCME between 2008 and 2012. The cohort consisted of 141 infants (92.9% younger than six-month old) and 133 non-infants (78.2% were between 19 and 58 years old). Among the ethnically diverse cohort, African American infants had the highest risks of SUD, and African American non-infants died at significantly younger age (23.7 years old, mean age-at-death) than those of other ethnicities (30.3 years old, mean age-at-death). A total of 22 previously classified cardiac channelopathy-associated variants and 24 novel putative channelopathy-associated variants were detected among the infants (13.5%) and non-infants (19.5%). Most channelopathy-associated variants involved the SCN5A gene (68.4% in infants, 50% in non-infants). We believe this is the first study assessing the role of cardiac channelopathy genes in a large and demographically diverse SUD population drawn from a single urban medical examiner's office in the United States. Our study supports that molecular testing for cardiac channelopathy is a valuable tool in SUD

  6. Orientational Phase Transition Around 274 K in C60 Single Crystal

    Institute of Scientific and Technical Information of China (English)

    徐亚伯; 何丕模; 杨宏顺; 郑萍; 余朝文; 陈兆甲; 张宣嘉; 李文铸

    1994-01-01

    The electrical conductivity of a C60 single crystal around 274 K and the specific heat of C60 crystals from 150 to 340 K have been measured.The delta-like specific heat peak at about 251 K related to the first-order phase transition has been reported.The activation energy change around 274 K and the lambda-like specific heat peak beginning at 270 K and ending at 310 K show that there is an orientational phase transition in fcc C60 crystals above 251 K.By taking the symmetry into consideration and further analyzing lambda-like specific heat peak and the activation energy change around 274 K,the conclusion has been reached that this new phase transition is an orientational structure transition from the merohedral twinning fcc to the orientationally disordered fcc.The temperature of free rotation of C60 molecules is about 281 K.

  7. 48 CFR 211.274-5 - Policy for assignment of Government-assigned serial numbers.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Policy for assignment of... DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE ACQUISITION PLANNING DESCRIBING AGENCY NEEDS Using and Maintaining Requirements Documents 211.274-5 Policy for assignment of...

  8. 40 CFR 81.274 - Mountain Counties Intrastate Air Quality Control Region.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Mountain Counties Intrastate Air... Air Quality Control Regions § 81.274 Mountain Counties Intrastate Air Quality Control Region. The Mountain Counties Intrastate Air Quality Control Region consists of the territorial area encompassed by...

  9. Complete Genome Sequence of Mycoplasma yeatsii Strain GM274B (ATCC 43094).

    Science.gov (United States)

    Calcutt, Michael J; Kent, Bethany N; Foecking, Mark F

    2015-04-23

    Mycoplasma yeatsii is a goat mycoplasma species that, although an obligate parasite, accommodates this lifestyle as an inapparent commensalist. High-frequency transformation has also been reported for this species. The complete 895,051-bp genome sequence of strain GM274B has been determined, enabling an analysis of the features of this potential cloning host.

  10. 33 CFR Appendix A to Part 274 - Preventive Safety Measures in Handling of Pesticides

    Science.gov (United States)

    2010-07-01

    ... protective clothing are rubber aprons, coveralls, chemical splash goggles, safety shoes, and hard hats. A... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Preventive Safety Measures in... Appendix A to Part 274—Preventive Safety Measures in Handling of Pesticides 1. Follow the label on...

  11. 17 CFR 274.11b - Form N-3, registration statement of separate accounts organized as management investment companies.

    Science.gov (United States)

    2010-04-01

    ... statement of separate accounts organized as management investment companies. 274.11b Section 274.11b... accounts organized as management investment companies. Form N-3 shall be used as the registration statement... offer variable annuity contracts to register as management investment companies. This form shall also...

  12. 20 CFR 667.274 - What health and safety standards apply to the working conditions of participants in activities...

    Science.gov (United States)

    2010-04-01

    ... working conditions of participants in activities under title I of WIA? 667.274 Section 667.274 Employees... and safety standards apply to the working conditions of participants in activities under title I of... working conditions of employees are equally applicable to working conditions of participants engaged...

  13. Looking into the Theory of Pulsar Accretion: Cen X-3 and XTE J1946+274

    CERN Document Server

    Marcu, Diana M; Gottlieb, Amy M; Wolff, Michael T; Becker, Peter A; Wilms, Joern; Ferrigno, Carlo; Wood, Kent S

    2015-01-01

    This is an overview of pulsar accretion modeling. The physics of pulsar accretion, i.e., the process of plasma flow onto the neutron star surface, can be constrained from the spectral properties of the X-ray source. We discuss a new implementation of the physical continuum model developed by Becker and Wolff (2007, ApJ 654, 435). The model incorporates Comptonized blackbody, bremsstrahlung, and cyclotron emission. We discuss preliminary results of applying the new tool to the test cases of Suzaku data of Cen X-3 and XTE J1946+274. Cen X-3 is a persistent accreting pulsar with an O-star companion observed during a bright period. XTE J1946+274 is a transient accreting pulsar with a Be companion observed during a dim period. Both sources show spectra that are well described with an empirical Fermi Dirac cutoff power law model. We extend the spectral analysis by making the first steps towards a physical description of Cen X-3 and XTE J1946+274.

  14. The reawakening of the sleeping X-ray pulsar XTE J1946+274

    CERN Document Server

    Müller, Sebastian; Caballero, Isabel; Pottschmidt, Katja; Fürst, Felix; Kreykenbohm, Ingo; Sagredo, Macarena; Obst, Maria; Wilms, Jörn; Ferrigno, Carlo; Rothschild, Richard E; Staubert, Rüdiger

    2012-01-01

    We report on a series of outbursts of the high mass X-ray binary XTE J1946+274 in 2010/2011 as observed with INTEGRAL, RXTE, and Swift. We discuss possible mechanisms resulting in the extraordinary outburst behavior of this source. The X-ray spectra can be described by standard phenomenological models, enhanced by an absorption feature of unknown origin at about 10 keV and a narrow iron K alpha fluorescence line at 6.4 keV, which are variable in flux and pulse phase. We find possible evidence for the presence of a cyclotron resonance scattering feature at about 25 keV at the 93% level. The presence of a strong cyclotron line at 35 keV seen in data from the source's 1998 outburst and confirmed by a reanalysis of these data can be excluded. This result indicates that the cyclotron line feature in XTE J1946+274 is variable between individual outbursts.

  15. ASSOCIATION BETWEEN MICROSATELLITE D6S274 POLYMORPHISM AND SCHIZOPHRENIA IN THE CHINESE POPULATION%江西地区汉族精神分裂症微卫星D6S274多态性分析

    Institute of Scientific and Technical Information of China (English)

    卢和丽; 袁也丰; 万爱兰; 万福生; 周小军; 章洁

    2011-01-01

    [目的]探讨江西地区汉族人群微卫星D6S274等位基因多态性与精神分裂症关系.[方法]提取江西地区汉族174例精神分裂症患者及174例健康体检者全血DNA并使用PE9600型PCR扩增仪对其进行扩增,所得PCR产物用ABI3730型基因分析仪自动进行电泳分离和基因检测.[结果]①正常人D6S274基因型频率符合Hardy-Wein-berg平衡定律(x2=39.81,P>0.05);②精神分裂症组D65274位点的172bp等位基因检出率为11.78%,正常对照组的检出率为4.60%,两者差异有统计学意义(x2=11.94,P<0.01);该位点其他各等位基因检出率差异无统计学意义(P>0.05).[结论]6号染色体短臂D6S274附近可能存在精神分裂症的易感基因.%[Objective] To explore association between microsatellite D6S274 polymorphism and schizophrenia. [Methods] DNA samples were collected from patients with schizophrenia (n = 174) and random population (re = 174) in Jiangxi Province. The microsatellite D6S274 were determined with the polymerase chain reaction. [Results] (D The distribution of the allele frequencies in D6S274 loci conformed to Hardy Weinberg equilibrium in the control groups (^ = 39.81, P > 0.05). ② The gene frequency of the allele 172 bp of D6S274 in schizophrenia group was higher than that in control group ( 11.78% vs4.60%, x2 = 11.94, P< 0.01). The frequencies of other alleles did not differ between the schizophrenia and controls. [ConClusion] D6S274 loci in the chromosome 6 may be associated withschizophienia. Gene associated with susceptibility to schizophrenia may exist in the microsatellite marker regions D6S274 of the chromosome 6p.

  16. 274例非小细胞肺癌临床特点分析%Clinical features with non- small- cell lung cancer: An analysis of 274 patients

    Institute of Scientific and Technical Information of China (English)

    陈衍; 韩晟; 薛妍; 刘文超

    2012-01-01

    目的 了解我国非小细胞肺癌(NSCLC)患者流行病学特点,为临床NSCLC的防治提供参考数据.方法 对某医科大学附属医院肿瘤科组织学确诊的274例NSCLC患者临床特点及其相关因素进行回顾性研究,并分析影响临床分期和病理的独立风险因子.结果 男女比例为1.88∶1.腺癌和鳞癌约占总样本的90%,晚期患者占67.88%.47.45%有吸烟史,约28.83%来自农村.女性、农村患者发病年龄明显低于男性及城市患者.性别、病理类型及手术史是影响临床分期的独立风险因素.女性、腺癌及未进行手术的患者,晚期的比例更高.性别、年龄及吸烟状态均为影响病理的独立风险因素.男性、≤60岁以及吸烟患者更易患鳞癌.无论吸烟与否,男性较女性更易患鳞癌.即使排除吸烟因素,女性也较男性更易患腺癌.结论 NSCLC的发病特点发生变化,应加强对女性、农村人群及中青年的肺癌普查,提高早期NSCLC的筛查率.%Objective To investigate the clinical features of patients with non- small - cell lung cancer (NSCLC) in China in order to provide clinical reference data for further prevention and treatment of NSCLC. Methods The clinical features of 274 cases of NSCLC histologically diagnosed in a university hospital were retrospectively analyzed. The independent influencing factors related to stage and pathology with Cox's regression analysis were studied. Results The male to female ratio was 1.88:1. Squamous cell carcinoma and adenocarcinoma accounted for neatly 90 % in the total sample. Patients were diagnosed with advanced stage (Ⅲ B - Ⅳ) accounted for 67.88 % . Patients with smoking habits accounted for 47.45 % and 28.83 % of them lived in ruraLareas. Multiple regression analysis showed that gender, pathology and surgery were the independent variables influencing clinical stage. Female who had adenocarcinoma and received no surgery had higher incidence of caner in their late

  17. Clasificación del traumatismo del bazo: Estudio de 274 pacientes

    Directory of Open Access Journals (Sweden)

    Eddy Sierra Enrique

    1997-08-01

    Full Text Available Se revisaron 274 historias clínicas que presentaron traumatismo del bazo, en el Hospital Militar "Comandante Manuel Fajardo Rivero" y Hospital Provincial Clinicoquirúrgico Docente, ambos de Santa Clara, durante los años 1988-1994. Se describe la clasificación del trauma esplénico grado 1, con 97 pacientes; grado 2, 53 pacientes; grado 3, 71 pacientes, los grados 2A,33 pacientes y grado 3B, 20 pacientes. Las complicaciones en los esplenectomizados fueron 40, para una morbilidad del 22,3 % y hubo 2 complicaciones en los pacientes a quienes se les realizó cirugía conservadora, para el 2,1 %. No hubo mortalidad en la cirugía conservadora, pero es de señalar que ocurrieron en los traumas de menor cuantía, los grados 1 y 2. Hubo 5 pacientes fallecidos en los esplenectomizados para el 2,7 % de mortalidad, y fue la mortalidad asociada de 9,8 %A number of 274 medical histories presenting with spleen injuries were revised at "Comandante Manuel Fajardo Rivero" Military Hospital, and at the Teaching and Provincial Clinico surgical Hospital of Santa Clara during 1988-1994. The classification of splenic trauma grade 1 with 97 patients; grade 2 with 53 patients; grade 3 with 71 patients, grade 2 A with 33 patients, and grade 3 B with 20 patients, is described. Complications in splectomized patients were found to be 40 accounting for a morbidity of 22.3 %. There were 2 complications in patients who underwent a conservative surgical procedure, accounting for 2.1 %. There was no mortality rate regarding conservative surgery, but injuries less severe grades 1 and 2 occurred. Five patients died in the group of splectomized patients accounting for 2.7 % of mortality; the associated mortality was 9.8 %

  18. Molecular mechanism and structural basis of gain-of-function of STAT1 caused by pathogenic R274Q mutation.

    Science.gov (United States)

    Fujiki, Ryoji; Hijikata, Atsushi; Shirai, Tsuyoshi; Okada, Satoshi; Kobayashi, Masao; Ohara, Osamu

    2017-04-14

    Gain-of-function (GOF) mutations in the STAT1 gene are critical for the onset of chronic mucocutaneous candidiasis (CMC) disease. However, the molecular basis for the gain of STAT1 function remains largely unclear. Here, we investigated the structural features of STAT1 GOF residues to better understand the impact of these pathogenic mutations. We constructed STAT1 alanine mutants of the α3 helix residues of the coiled-coil domain, which are frequently found in CMC pathogenic mutations, and measured their transcriptional activities. Most of the identified GOF residues were located inside the coiled-coil domain stem structure or at the protein surface of the anti-parallel dimer interface. Unlike those, Arg-274 was adjacent to the DNA-binding domain. In addition, Arg-274 was found to functionally interact with Gln-441 in the DNA-binding domain. Because Gln-441 is located at the anti-parallel dimer contact site, Gln-441 reorientation by Arg-274 mutation probably impedes formation of the dimer. Further, the statistical analysis of RNA-seq data with STAT1-deficient epithelial cells and primary T cells from a CMC patient revealed that the R274Q mutation affected gene expression levels of 66 and 76 non-overlapping RefSeq genes, respectively. Because their transcription levels were only slightly modulated by wild-type STAT1, we concluded that the R274Q mutation increased transcriptional activity but did not change dramatically the repertoire of STAT1 targets. Hence, we provide a novel mechanism of STAT1 GOF triggered by a CMC pathogenic mutation. © 2017 by The American Society for Biochemistry and Molecular Biology, Inc.

  19. Culture conditions of Roseobacter strain 27-4 affect its attachment and biofilm formation as quantified by real-time PCR

    DEFF Research Database (Denmark)

    Bruhn, Jesper Bartholin; Haagensen, Janus Anders Juul; Bagge-Ravn, D.;

    2006-01-01

    The fish probiotic bacterium Roseobacter strain 27-4 grows only as rosettes and produces its antibacterial compound under static growth conditions. It forms three-dimensional biofilms when precultured under static conditions. We quantified attachment of Roseobacter strain 27-4 using a direct real...

  20. 8 CFR 274a.7 - Pre-enactment provisions for employees hired prior to November 7, 1986 or in the CNMI prior to...

    Science.gov (United States)

    2010-01-01

    ... 8 CFR 274a.2(b)(1)(viii)), except those individuals described in 8 CFR 274a.2(b)(1)(viii)(A)(7)(iii... CNMI prior to the transition program effective date as defined in 8 CFR 1.1. (b) For purposes of this..., situations in which an employee is subject to seasonal employment; or (3) Is excluded or deported from...

  1. Genome Sequencing and Comparative Analysis of the Biocontrol Agent Trichoderma harzianum sensu stricto TR274

    Energy Technology Data Exchange (ETDEWEB)

    Steindorff, Andrei S.; Noronha, Elilane F.; Ulhoa, Cirano J.; Kuo, Alan; Salamov, Asaf A.; Haridas, Sajeet; Riley, Robert W.; Druzhinina, Irina S.; Kubicek, Christian P.; Grigoriev, Igor V.

    2015-03-17

    Biological control is a complex process which requires many mechanisms and a high diversity of biochemical pathways. The species of Trichoderma harzianum are well known for their biocontrol activity against many plant pathogens. To gain new insights into the biocontrol mechanism used by T. harzianum, we sequenced the isolate TR274 genome using Illumina. The assembly was performed using AllPaths-LG with a maximum coverage of 100x. The assembly resulted in 2282 contigs with a N50 of 37033bp. The genome size generated was 40.8 Mb and the GC content was 47.7%, similar to other Trichoderma genomes. Using the JGI Annotation Pipeline we predicted 13,932 genes with a high transcriptome support. CEGMA tests suggested 100% genome completeness and 97.9% of RNA-SEQ reads were mapped to the genome. The phylogenetic comparison using orthologous proteins with all Trichoderma genomes sequenced at JGI, corroborates the Trichoderma (T. asperellum and T. atroviride), Longibrachiatum (T. reesei and T. longibrachiatum) and Pachibasium (T. harzianum and T. virens) section division described previously. The comparison between two Trichoderma harzianum species suggests a high genome similarity but some strain-specific expansions. Analyses of the secondary metabolites, CAZymes, transporters, proteases, transcription factors were performed. The Pachybasium section expanded virtually all categories analyzed compared with the other sections, specially Longibrachiatum section, that shows a clear contraction. These results suggests that these proteins families have an important role in their respective phenotypes. Future analysis will improve the understanding of this complex genus and give some insights about its lifestyle and the interactions with the environment.

  2. Multi-scalar influences on mortality change over time in 274 European cities.

    Science.gov (United States)

    Richardson, Elizabeth A; Moon, Graham; Pearce, Jamie; Shortt, Niamh K; Mitchell, Richard

    2017-04-01

    Understanding determinants of urban health is of growing importance. Factors at multiple scales intertwine to influence health in cities but, with the growing autonomy of some cities from their countries, city population health may be becoming more a matter for city-level rather than national-level policy and action. We assess the importance of city, country, and macroregional (Western and East-Central Europe) scales to mortality change over time for 274 cities (population 80 million) from 27 European countries. We then investigate whether mortality changes over time are related to changes in city-level affluence. Using Urban Audit data, all-age all-cause standardised mortality ratios (SMRs) for males and females were calculated at three time points (wave one 1999-2002, wave two 2003-2006, and wave three 2007-2009) for each city. Multilevel regression was used to model the SMRs as a function of survey wave and city region gross domestic product (GDP) per 1000 capita. SMRs declined over time and the substantial East-West gap narrowed slightly. Variation at macroregion and country scales characterised SMRs for women in Western and East-Central European cities, and SMRs for men in East-Central European cities. Between-city variation was evident for male SMRs in Western Europe. Changes in city-region GDP per capita were not associated with changes in mortality over the study period. Our results show how geographical scales differentially impact urban mortality. We conclude that changes in urban health should be seen in both city and wider national and macroregional contexts.

  3. B7-H1 (PD-L1, CD274) suppresses host immunity in T-cell lymphoproliferative disorders

    OpenAIRE

    Wilcox, Ryan A.; Feldman, Andrew L.; Wada, David A.; Yang, Zhi-Zhang; Comfere, Nneka I.; Dong, Haidong; Kwon, Eugene D.; Novak, Anne J.; Markovic, Svetomir N.; Mark R Pittelkow; Witzig, Thomas E.; Ansell, Stephen M.

    2009-01-01

    Stromal elements present within the tumor microenvironment may suppress host immunity and promote the growth of malignant lymphocytes in B cell–derived non-Hodgkin lymphoma (NHL). In contrast, little is known about the microenvironment's role in T cell–derived NHL. B7-H1 (PD-L1, CD274), a member of the B7 family of costimulatory/coinhibitory ligands expressed by both malignant cells and stromal cells within the tumor microenvironment, has emerged as an important immune modulator capable of su...

  4. Core drilling of hydco drillholes ONK-PP262 and ONK-PP274 in ONKALO at Olkiluoto 2010

    Energy Technology Data Exchange (ETDEWEB)

    Toropainen, V. [Suomen Malmi Oy, Espoo (Finland)

    2011-10-15

    Suomen Malmi Oy (Smoy) core drilled two drillholes for HYDCO-program in ONKALO at Eurajoki, Olkiluoto in 2010. The drillhole ONK-PP262 was drilled in May 2010 and the drillhole ONK-PP274 in December 2010. The lengths of the drillholes are 25.02 and 23.88 m respectively. The drillholes are 75.7 mm by diameter. The drillholes were drilled in the investigation niche 4 at the access tunnel chainage 3747. The hydraulic DE 130 drilling rig was used. The drilling water was taken from the ONKALO drilling water pipeline and premixed sodium fluorescein was used as a label agent in the drilling water. The drillholes were measured with EMS deviation survey tool. In addition to drilling the drillcores were logged and reported by geologist. Geological logging included the following parameters: lithology, foliation, fracture parameters, fractured zones, core loss, weathering, fracture frequency, RQD and rock quality. The main rock types in the drillholes are veined gneiss and pegmatitic granite. The average fracture frequencies in both drill cores are 1.4 pcs/m. The average RQD values in the drillcores are 97.2 % (ONK-PP262) and 98.6 % (ONK-PP274). (orig.)

  5. Detection of a large Be circumstellar disk during X-ray quiescence of XTE J1946+274

    CERN Document Server

    Arabaci, M Ozbey; Gutierrez-Soto, J; Zurita, C; Nespoli, E; Suso, J; Kiaeerad, F; Garcia-Rojas, J; Kiziloglu, U

    2014-01-01

    We present a multiwavelength study of the Be/X-ray binary system XTE J1946+274 with the main goal of better characterizing its behavior during X-ray quiescence. We aim to shed light on the mechanism which triggers the X-ray activity for this source. XTE J1946+274 was observed by Chandra-ACIS during quiescence in 2013 March 12. In addition, this source has been monitored from the ground-based astronomical observatories of El Teide (Tenerife, Spain), Roque de los Muchachos (La Palma, Spain) and Sierra Nevada (Granada, Spain) since 2011 September, and from the TUBITAK National Observatory (Antalya, Turkey) since 2005 April. We have performed spectral and photometric temporal analyses in order to investigate the quiescent state and transient behavior of this binary system. In 2006, a long mass ejection event took place from the Be star, lasting for about seven years. We also found that a large Be circumstellar disk was present during quiescence, although major X-ray activity was not observed. We made an attempt t...

  6. The Candidate Cluster and Protocluster Catalog (CCPC) of Spectroscopically Identified Structures Spanning 2.74 < z < 3.71

    Science.gov (United States)

    Franck, J. R.; McGaugh, S. S.

    2016-02-01

    We developed a search methodology to identify galaxy protoclusters at z\\gt 2.74 and implemented it on a sample of ˜14,000 galaxies with previously measured redshifts. The results of this search are recorded in the Candidate Cluster and Protocluster Catalog (CCPC). The catalog contains 12 clusters that are highly significant overdensities ({δ }{gal}\\gt 7), 6 of which were previously known. We also identify another 31 candidate protoclusters (including four previously identified structures) of lower overdensities. CCPC systems vary over a wide range of physical sizes and shapes, from small, compact groups to large, extended, and filamentary collections of galaxies. This variety persists in the range from z = 3.71 to z = 2.74. These structures exist as galaxy overdensities ({δ }{gal}) with a mean value of 2, similar to the values found for other protoclusters in the literature. The median number of galaxies for CCPC systems is 11. Virial mass estimates are large for these redshifts, with 13 cases apparently having M\\gt {10}15 {M}⊙ . If these systems are virialized, such masses would pose a challenge to ΛCDM.

  7. The candidate cluster and protocluster catalog (CCPC) of spectroscopically identified structures spanning $2.74 < z < 3.71$

    CERN Document Server

    Franck, J R

    2015-01-01

    We have developed a search methodology to identify galaxy protoclusters at $z>2.74$, and implemented it on a sample of $\\sim$14,000 galaxies with previously measured redshifts. The results of this search are recorded in the Candidate Cluster and Protocluster Catalog (CCPC). The catalog contains 12 clusters that are highly significant overdensities ($\\delta_{gal}>7$), 6 of which are previously known. We also identify another 31 candidate protoclusters (including 4 previously identified structures) of lower overdensity. CCPC systems vary over a wide range of physical sizes and shapes, from small, compact groups to large, extended, and filamentary collections of galaxies. This variety persists over the range from $z=3.71$ to $z=2.74$. These structures exist as galaxy overdensities ($\\delta_{gal}$) with a mean value of 2, similar to the values found for other protoclusters in the literature. The median number of galaxies for CCPC systems is 11. Virial mass estimates are large for these redshifts, with thirteen ca...

  8. 274例梗阻性无精子症经闭合式穿刺取精行ICSI治疗的临床分析%Analysis Clinical Treatment of 274 Cases With Obstructive Azoospermatism Close Needle Aspiration of ICSI

    Institute of Scientific and Technical Information of China (English)

    刘东方; 曲文玉; 董树林

    2015-01-01

    目的:探讨梗阻性无精子症经闭合式穿刺取精行ICSI治疗的临床效果。方法选取我院行外科闭合式穿刺取精术274例,A组睾丸穿刺取精164例,B组附睾穿刺取精110例,对上述病例的临床资料进行回顾性分析。结果睾丸体积正常的取精成功率高于睾丸体积偏小者, P<0.05,差异具有统计学意义。血清促卵泡刺激素(FSH)水平正常的取精成功率高于FSH增高者,P<0.05,差异具有统计学意义。对比睾丸穿刺组与附睾穿刺组比较术后并发症发生率和术后恢复时间,P<0.05,差异具有统计学意义。结论睾丸穿刺取精术操作简单创伤较小,术后并发症轻,感染、水肿及出血率均低于附睾穿刺取精,且术后恢复时间短。%Objective To explore the clinical effect on 274 cases with obstructive azoospermatism close needle aspiration of ICSI. Methods Selected 274 cases with surgical closure type piercing fine extraction in our hospital, 164 cases of group A piercing testicular, group B epididymis puncture in 110 cases, retrospectively analyzed the clinical data of the above cases. Results The volume normal testicular sperm extraction for managing the success rate was higher than testicular volume by outsiders, P<0.05, had difference statistically signiifcance. Serum cu follicle-stimulating hormone (FSH) levels were normal for ifne success rate increased higher than that of FSH, P<0.05, had difference statistically signiifcance. While testicular biopsy and epididymis puncture group less postoperative complications and postoperative recovery time, P<0.05, had difference statistically signiifcance. Conclusion Puncture testicular sperm extraction for managing the operation is simple and less trauma, postoperative complications, infection, edema and hemorrhage rate were lower than that of epididymis puncture in essence, and postoperative recovery time is short.

  9. The Real Time Mixing Module Design for HDTV Data of SMPTE 274M and PC Video Data

    Institute of Scientific and Technical Information of China (English)

    魏江力; 赵保军; 韩月秋

    2003-01-01

    A real time mixing module for high definition television (HDTV) data of SMPTE 274M and PC video data is designed. The hardware implementation, algorithm and simulation of the mixing module are given. In order to improve the capability of data processing, an anti-fuse FPGA chip and a mechanism of pipelining and modularization are adopted. With 6 parallel LUTs and a fast algorithm, it can mix 4∶2∶2 component signals in luminance and chrominance space respectively in real time. According to the simulation, the module has the ability to mix the uncompressed HDTV data with PC video data in real time, which can not be fulfilled by current ASIC chips. Furthermore, it can be extended to multi-stage mixing with the thoughts implied by the design. The mixing module can be widely used in HDTV production systems.

  10. Geophysical logging and imaging of shallow drillholes ONK-PP262 and ONK-274 at Olkiluoto in 2010

    Energy Technology Data Exchange (ETDEWEB)

    Tarvainen, A.-M. [Suomen Malmi Oy, Espoo (Finland)

    2011-11-15

    Suomen Malmi Oy conducted geophysical drillhole logging as well as optical and acoustic imaging of shallow drillholes ONK-PP262 and ONK-PP274 at ONKALO in the investigation niche ONK-TKU-4 (Hydco) in May and in December 2010. The survey is a part of Posiva Oy's detailed investigation program for the final disposal of spent nuclear fuel. The assignment included the field work and data processing. The report describes field operation, equipment as well as processing procedures and shows the obtained results and an analysis of their quality in the appendices. The raw and processed data are delivered digitally in WellCAD, PDF and Excel format. (orig.)

  11. Thromboembolic risk in 16 274 atrial fibrillation patients undergoing direct current cardioversion with and without oral anticoagulant therapy

    DEFF Research Database (Denmark)

    Hansen, Morten Lock; Jepsen, Rikke Malene H G; Olesen, Jonas Bjerring;

    2015-01-01

    AIMS: To study the risk of thromboembolism in a nationwide cohort of atrial fibrillation patients undergoing direct current (DC) cardioversion with or without oral anticoagulant coverage. METHODS AND RESULTS: A retrospective study of 16 274 patients in Denmark discharged from hospital after a first......-time DC cardioversion for atrial fibrillation between 2000 and 2008. Use of oral anticoagulant therapy within 90 days prior and 360 days after DC cardioversion was obtained from the Danish Register of Medicinal Product Statistics. The risk of thromboembolism was estimated by calculating incidence rates...... and by multivariable adjusted Cox proportional-hazard models. During the initial 30 days following discharge, the thromboembolic incidence rate was 10.33 per 100 patient-years for the no prior oral anticoagulant therapy group [n = 5084 (31.2%)], as compared with 4.00 per 100 patient-years for the prior oral...

  12. Role of the conserved arginine 274 and histidine 224 and 228 residues in the NuoCD subunit of complex I from Escherichia coli.

    Science.gov (United States)

    Belevich, Galina; Euro, Liliya; Wikström, Mårten; Verkhovskaya, Marina

    2007-01-16

    The conserved arginine 274 and histidine 224 and 228 residues in subunit NuoCD of complex I from Escherichia coli were substituted for alanine. The wild-type and mutated NuoCD subunit was expressed on a plasmid in an E. coli strain bearing a nuoCD deletion. Complex I was fully expressed in the H224A and H228A mutants, whereas the R274A mutation yielded approximately 50% expression. Ubiquinone reductase activity of complex I was studied in membranes and with purified enzyme and was 50% and 30% of the wild-type activity in the H224A and H228A mutants, respectively. The activity of R274A was less than 5% of the wild type in membranes but 20% in purified complex I. Rolliniastatin inhibited quinone reductase activity in the mutants with similar affinity as in the wild type, indicating that the quinone-binding site was not significantly altered by the mutations. Ubiquinone-dependent superoxide production by complex I was similar to the wild type in the R274A mutant but slightly higher in the H224A and H228A mutants. The EPR spectra of purified complex I from the H224A and H228A mutants did not differ from the wild type. In contrast, the signals of the N2 cluster and another fast-relaxing [4Fe-4S] cluster, tentatively assigned as N6b, were drastically decreased in the NADH-reduced R274A mutant enzyme but reappeared on further reduction with dithionite. These findings show that the redox potential of the N2 and N6b centers is shifted to more negative values by the R274A mutation. Purified complex I was reconstituted into liposomes, and electric potential was generated across the membrane upon NADH addition in all three mutant enzymes, suggesting that none of the mutations directly affect the proton-pumping machinery.

  13. 17 CFR 274.302 - Form N-27I-1, notice of right of withdrawal and refund for variable life insurance...

    Science.gov (United States)

    2010-04-01

    ... of withdrawal and refund for variable life insurance contractholders required pursuant to Rule 6e-2... for Exemptions § 274.302 Form N-27I-1, notice of right of withdrawal and refund for variable life insurance contractholders required pursuant to Rule 6e-2 (§ 270.6e-2 of this chapter). Editorial Note:...

  14. 50 CFR 660.393 - Latitude/longitude coordinates defining the 100 fm (183 m) through 150 fm (274 m) depth contours.

    Science.gov (United States)

    2010-10-01

    ... 50 Wildlife and Fisheries 9 2010-10-01 2010-10-01 false Latitude/longitude coordinates defining... Latitude/longitude coordinates defining the 100 fm (183 m) through 150 fm (274 m) depth contours. Boundaries for RCAs are defined by straight lines connecting a series of latitude/longitude coordinates....

  15. Evaluation of a conserved HA274-288 epitope to detect antibodies to highly pathogenic avian influenza virus H5N1 in Indonesian commercial poultry.

    Science.gov (United States)

    Wawegama, Nadeeka K; Tarigan, Simson; Indriani, Risa; Selleck, Paul; Adjid, Rm Abdul; Syafriati, Tati; Hardiman; Durr, Peter A; Ignjatovic, Jagoda

    2016-08-01

    A peptide enzyme linked immunosorbent assay (ELISA) based on an epitope in the haemagglutinin (HA) of avian influenza virus H5N1, amino acid positions 274-288 (HA274-288) was evaluated for detection of H5N1-specific antibodies. An optimized ELISA based on the tetrameric form of the HA274-288 epitope designated MP15 gave low background with non-immune chicken sera and detected vaccinated and infected birds. The HA274-288 epitope was highly conserved in Indonesian H5N1 strains and antibody responses were detected in the majority of the vaccinated chickens regardless of the H5N1 strain used for vaccination. The HA274-288 epitope was also conserved in the majority of H5N1 strains from the neighbouring Asian region, and other H5 subtypes potentially allowing for a wider use of the MP15 ELISA in H5N1 vaccinated and infected flocks. The MP15 ELISA results correlated significantly with haemagglutination inhibition (HI) test results and test sensitivity and specificity were 87% and 92%, respectively. The MP15 ELISA titres were significantly higher than the HI titres in all immune sera allowing for sera to be tested at a single dilution of 1:400 which is of advantage in routine surveillance. The study indicated that the MP15 ELISA is potentially useful for serological detection of H5N1 vaccinated or infected poultry and to have some advantages over the standard HI test for routine monitoring of flocks' immunity after vaccination.

  16. Oncogenic kinase NPM/ALK induces through STAT3 expression of immunosuppressive protein CD274 (PD-L1, B7-H1).

    Science.gov (United States)

    Marzec, Michal; Zhang, Qian; Goradia, Ami; Raghunath, Puthiyaveettil N; Liu, Xiaobin; Paessler, Michele; Wang, Hong Yi; Wysocka, Maria; Cheng, Mangeng; Ruggeri, Bruce A; Wasik, Mariusz A

    2008-12-30

    The mechanisms of malignant cell transformation caused by the oncogenic, chimeric nucleophosmin (NPM)/anaplastic lymphoma kinase (ALK) remain only partially understood, with most of the previous studies focusing mainly on the impact of NPM/ALK on cell survival and proliferation. Here we report that the NPM/ALK-carrying T cell lymphoma (ALK+TCL) cells strongly express the immunosuppressive cell-surface protein CD274 (PD-L1, B7-H1), as determined on the mRNA and protein level. The CD274 expression is strictly dependent on the expression and enzymatic activity of NPM/ALK, as demonstrated by inhibition of the NPM/ALK function in ALK+TCL cells by the small molecule ALK inhibitor CEP-14083 and by documenting CD274 expression in IL-3-depleted BaF3 cells transfected with the wild-type NPM/ALK, but not the kinase-inactive NPM/ALK K210R mutant or empty vector alone. NPM/ALK induces CD274 expression by activating its key signal transmitter, transcription factor STAT3. STAT3 binds to the CD274 gene promoter in vitro and in vivo, as shown in the gel electromobility shift and chromatin immunoprecipitation assays, and is required for the PD-L1 gene expression, as demonstrated by siRNA-mediated STAT3 depletion. These findings identify an additional cell-transforming property of NPM/ALK and describe a direct link between an oncoprotein and an immunosuppressive cell-surface protein. These results also provide an additional rationale to therapeutically target NPM/ALK and STAT3 in ALK+TCL. Finally, they suggest that future immunotherapeutic protocols for this type of lymphoma may need to include the inhibition of NPM/ALK and STAT3 to achieve optimal clinical efficacy.

  17. The relationship of 274 children with respiratory infection and routine blood performance%274例住院患儿呼吸道病原体感染与白细胞数量变化的关系

    Institute of Scientific and Technical Information of China (English)

    袁红; 熊晓飞

    2013-01-01

    Objective: To discuss the relationship of children with respiratory infection and routine blood performance. Method: The investigated method is to analyze 274 hospitalized children with respiratory pathogen infection,and divide them into five categories according to the IFA detection results and clinical diagnosis:Simple virus infection group,the group combination of respiratory pathogen outside infection, MP merge virus and bacteria infection group, MP infection group, MP merge virus infection group, Compare the 5 groups of blood routine performance. Results: It shows that MP merger virus infections is the first-line reason in the 278 cases, accounting for 48.18%,and bacteria, MP merge viruses infection accounted for 7.66%, viruses and MP infection accounted for 20.07% and 16.79% respectively. The difference of Group 2 and other group is statistical y significant in WBC count (p <0.05), the difference of Group 4 and Group 3 is statistical y significant in lymphocyte count (p <0.05). Conclusions: MP merger virus infection is a common pattern of hospitalized children. The leukocytes count of the group combination of respiratory system outside damage is higher than respiratory pathogens infection disease in children.%目的:探讨儿童呼吸道感染情况及与血常规表现的关系。方法:回顾性分析274名住院呼吸道感染患儿病原体的感染情况,并将其按I F A检测结果和临床诊断分为5组:单纯病毒感染组、合并呼吸道病原体感染以外疾病组、细菌合并肺炎支原体及病毒感染组、肺炎支原体感染组、肺炎支原体合并病毒感染组(第5组),比较该5组患儿的血常规表现。结果:肺炎支原体合并病毒感染占呼吸道感染患儿首位(48.18%),细菌合并肺炎支原体及病毒感染占7.66%,病毒和肺炎支原体单独感染各占20.07%和16.79%。第2组的白细胞总数与其他各组的比较差异均有统计学意义(p<0.05),第4组与第3组

  18. 274 REVIEW ARTICLE

    African Journals Online (AJOL)

    boaz

    History and examination was conducted on all ... 225.3±97.7. 34.5±4.8. 11.4±1.9. 33.3±26.0. 3(n=200). 346.0±238.5. 5.5±2.5. 2.2±1.2. 0.8±0.8 .... Donald RH, Qiuhu S, Aileen PM etal. Assessment .... The Canada Journal of human sexuality.

  19. Corrective Action Decision Document/Closure Report for Corrective Action Unit 274: Septic Systems, Nevada Test Site, Nevada, Rev. No.: 0

    Energy Technology Data Exchange (ETDEWEB)

    Grant Evenson

    2006-09-01

    This Corrective Action Decision Document/Closure Report has been prepared for Corrective Action Unit 274, Septic Systems, Nevada Test Site (NTS), Nevada in accordance with the ''Federal Facility Agreement and Consent Order'' (1996). Corrective Action Unit (CAU) 274 is comprised of five corrective action sites (CASs): (1) CAS 03-02-01, WX-6 ETS Building Septic System; (2) CAS 06-02-01, Cesspool; (3) CAS 09-01-01, Spill Site; (4) CAS 09-05-01, Leaching Pit; and (5) CAS 20-05-01, Septic System. The purpose of this Corrective Action Decision Document/Closure Report is to provide justification and documentation supporting the closure of CAU 274 with no further corrective action. To achieve this, corrective action investigation (CAI) activities were performed from November 14 through December 17, 2005 as set forth in the CAU 274 Corrective Action Investigation Plan. The purpose of the CAI was to fulfill the following data needs as defined during the data quality objective (DQO) process: (1) Determine whether contaminants of concern (COCs) are present. (2) If contaminants of concern are present, determine their nature and extent. (3) Provide sufficient information and data to complete appropriate corrective actions. The CAU 274 dataset from the investigation results was evaluated based on the data quality indicator parameters. This evaluation demonstrated the quality and acceptability of the dataset for use in fulfilling the DQO data needs. Analytes detected during the CAI were evaluated against final action levels (FALs) established in this document. No analytes were detected at concentrations exceeding the FALs. No COCs have been released to the soil at CAU 274, and corrective action is not required. Therefore, the DQO data needs were met, and it was determined that no corrective action based on risk to human receptors is necessary for the site. All FALs were calculated using the industrial site worker scenario except for benzo(a)pyrene, which was

  20. Physical and underway data collected aboard the THOMAS G. THOMPSON during cruise TN274 in the North Pacific Ocean and Philippine Sea from 2012-01-25 to 2012-02-21 (NODC Accession 0104371)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NODC accession 0104371 includes physical and underway data collected aboard the THOMAS G. THOMPSON during cruise TN274 in the North Pacific Ocean and Philippine Sea...

  1. 急诊抢救室处理非创伤急性腹痛274例临床调查及分析

    Institute of Scientific and Technical Information of China (English)

    梁亚鹏; 刘志祯; 尹其翔

    2015-01-01

    目的:对274例经急诊抢救室处理的非创伤急性腹痛患者临床资料进行回顾、总结、分析,强调对致命性非创伤急性腹痛的认识,提高抢救成功率。方法回顾急诊抢救室处理的274例以急性腹痛为主诉的非创伤患者的临床资料,对其病史、症状、体征、辅助检查及最终诊断进行总结、分析。结果经急诊抢救室处理以急性腹痛为主诉的非创伤患者,可迅速致命的疾病占12.04%(33例),延误病情后果严重可能危及生命的疾病占16.42%(45例),两者相加占28.46%。结论经急诊抢救室处理的非创伤急性腹痛潜在危险性巨大,需高度重视鉴别诊断,重点排除致命性疾病,从而改善预后。%Objective Through retrospective analysis of 274 cases with non traumatic acute abdominal pain managed in emergency rescue room, in order to strengthen the understanding of lethal acute abdominal pain and improve the success rate of rescue.Methods 274 patients with non traumatic acute abdominal pain managed in emergency rescue room of the affi liated hospital of Jiangsu university from January 2013 to December 2013 were analyzed retrospectively. The history, symptoms, signs, assistant examination andfi nal diagnosis of the patients were summarized and the focus was lethal acute abdominal pain.Results Among the patients with non traumatic acute abdominal pain managed in emergency rescue room, rapidly fatal diseases accounted for 12.04%(33 cases), life-threatening diseases accounted for 16.42%(45 cases). The two together accounted for 28.46%.Conclusion There was great potential medical risk in patients with non traumatic acute abdominal pain managed in emergency rescue room. We need to attach great importance to the differential diagnosis, emphatically exclude lethal disease, and improve the prognosis.

  2. The Transient Accereting X-Ray Pulsar XTE J1946+274: Stability of the X-Ray Properties at Low Flux and Updated Orbital Solution

    CERN Document Server

    Marcu-Cheatham, Diana M; Kühnel, Matthias; Müller, Sebastian; Falkner, Sebastian; Caballero, Isabel; Finger, Mark H; Jenke, Peter J; Wilson-Hodge, Colleen A; Fürst, Felix; Grinberg, Victoria; Hemphill, Paul B; Kreykenbohm, Ingo; Klochkov, Dmitry; Rothschild, Richard E; Terada, Yukikatsu; Enoto, Teruaki; Iwakiri, Wataru; Wolff, Michael T; Becker, Peter A; Wood, Kent S; Wilms, Jöern

    2015-01-01

    We present a timing and spectral analysis of the X-ray pulsar XTE J1946+274 observed with Suzaku during an outburst decline in 2010 October and compare with previous results. XTE J1946+274 is a transient X-ray binary consisting of a Be-type star and a neutron star with a 15.75 s pulse period in a 172 d orbit with 2-3 outbursts per orbit during phases of activity. We improve the orbital solution using data from multiple instruments. The X-ray spectrum can be described by an absorbed Fermi-Dirac cutoff power law model along with a narrow Fe K line at 6.4 keV and a weak Cyclotron Resonance Scattering Feature (CRSF) at ~35 keV. The Suzaku data are consistent with the previously observed continuum flux versus iron line flux correlation expected from fluorescence emission along the line of sight. However, the observed iron line flux is slightly higher, indicating the possibility of a higher iron abundance or the presence of non-uniform material. We argue that the source most likely has only been observed in the sub...

  3. The Effect of a Novel c.820C>T (Arg274Trp) Mutation in the Mitofusin 2 Gene on Fibroblast Metabolism and Clinical Manifestation in a Patient

    Science.gov (United States)

    Kawalec, Maria; Kabzińska, Dagmara; Kochański, Andrzej; Krzyśko, Krystiana A.; Zabłocka, Barbara

    2017-01-01

    Charcot-Marie-Tooth disease type 2A (CMT2A) is an autosomal dominant axonal peripheral neuropathy caused by mutations in the mitofusin 2 gene (MFN2). Mitofusin 2 is a GTPase protein present in the outer mitochondrial membrane and responsible for regulation of mitochondrial network architecture via the fusion of mitochondria. As that fusion process is known to be strongly dependent on the GTPase activity of mitofusin 2, it is postulated that the MFN2 mutation within the GTPase domain may lead to impaired GTPase activity, and in turn to mitochondrial dysfunction. The work described here has therefore sought to verify the effects of MFN2 mutation within its GTPase domain on mitochondrial and endoplasmic reticulum morphology, as well as the mtDNA content in a cultured primary fibroblast obtained from a CMT2A patient harboring a de novo Arg274Trp mutation. In fact, all the parameters studied were affected significantly by the presence of the mutant MFN2 protein. However, using the stable model for mitofusin 2 obtained by us, we were next able to determine that the Arg274Trp mutation does not impact directly upon GTP binding. Such results were also confirmed for GTP-hydrolysis activity of MFN2 protein in patient fibroblast. We therefore suggest that the biological malfunctions observable with the disease are not consequences of impaired GTPase activity, but rather reflect an impaired contribution of the GTPase domain to other MFN2 activities involving that region, for example protein-protein interactions. PMID:28076385

  4. THE DETECTION OF ANTI-HBs,ANTI-HBc,AND HBV-DNA OF 2 274 BLOOD DONORS WITH HBsAg NEGATIVE%2 274名HBsAg阴性献血员抗-HBs、抗-HBc、HBV-DNA检测结果分析

    Institute of Scientific and Technical Information of China (English)

    许顺姬

    2007-01-01

    [目的]检测2 274名HBsAg阴性献血员血清抗-HBs、抗-HBc、HBV-DNA,探讨献血员筛查中检测抗-HBs、抗-HBc的必要性.[方法]对2 274名HBsAg阴性献血员血清ELISA法检测抗-HBs、抗-HBc,用PCR法检测HBV-DNA.[结果]检测者2 274名中①抗-HBs阳性/抗-HBc阴性59.3%,HBV-DNA阳性率0.2%;②抗-HBs阴性/抗-HBc阴性17.4%,HBV-DNA阳性率0.3%;③抗-HBs阴性/抗-HBc阳性1.4%,HBV-DNA阳性率6.3%:④抗HBs阳性/抗-HBc阳性21.9%,HBV-DNA阳性率0.2%.[结论]抗-HBs阴性/抗-HBc阳性群体中HBV-DNA阳性率最高(6.3%),提示献血员筛查中检测抗-HBs、抗-HBc,可以降低通过输血途径的感染率.

  5. THE TRANSIENT ACCRETING X-RAY PULSAR XTE J1946+274: STABILITY OF X-RAY PROPERTIES AT LOW FLUX AND UPDATED ORBITAL SOLUTION

    Energy Technology Data Exchange (ETDEWEB)

    Marcu-Cheatham, Diana M.; Pottschmidt, Katja [CRESST and Department of Physics, University of Maryland Baltimore County, 1000 Hilltop Circle, Baltimore, MD 21250 (United States); Kühnel, Matthias; Müller, Sebastian; Falkner, Sebastian; Kreykenbohm, Ingo [Dr. Karl Remeis-Observatory and ECAP, University Erlangen-Nuremberg, Sternwartstr. 7, Bamberg (Germany); Caballero, Isabel [Laboratoire AIM, CEA/IRFU, CNRS/INSU, Université Paris Diderot, CEA DSM/IRFU/SAp, F-91191 Gif-sur-Yvette (France); Finger, Mark H. [Universities Space Research Association, National Space Science and Technology Center, 320 Sparkman Drive, Huntsville, AL 35805 (United States); Jenke, Peter J. [University of Alabama in Huntsville, 301 Sparkman Drive, Huntsville, AL 35899 (United States); Wilson-Hodge, Colleen A. [Astrophysics Office, ZP 12, NASA Marshall Space Flight Center, Huntsville, AL 35812 (United States); Fürst, Felix [Cahill Center for Astronomy and Astrophysics, California Institute of Technology, Pasadena, CA 91125 (United States); Grinberg, Victoria [Massachusetts Institute of Technology, Kavli Institute for Astrophysics, Cambridge, MA 02139 (United States); Hemphill, Paul B.; Rothschild, Richard E. [University of California, San Diego, Center for Astrophysics and Space Sciences, 9500 Gilman Drive, La Jolla, CA 92093-0424 (United States); Klochkov, Dmitry [Institut für Astronomie und Astrophysik, Universität Tübingen (IAAT), Sand 1, Tübingen (Germany); Terada, Yukikatsu [Graduate School of Science and Engineering, Saitama University, 255 Simo-Ohkubo, Sakura-ku, Saitama City, Saitama 338-8570 (Japan); and others

    2015-12-10

    We present a timing and spectral analysis of the X-ray pulsar XTE J1946+274 observed with Suzaku during an outburst decline in 2010 October and compare with previous results. XTE J1946+274 is a transient X-ray binary consisting of a Be-type star and a neutron star with a 15.75 s pulse period in a 172 days orbit with 2–3 outbursts per orbit during phases of activity. We improve the orbital solution using data from multiple instruments. The X-ray spectrum can be described by an absorbed Fermi–Dirac cut-off power-law model along with a narrow Fe Kα line at 6.4 keV and a weak Cyclotron Resonance Scattering Feature (CRSF) at ∼35 keV. The Suzaku data are consistent with the previously observed continuum flux versus iron line flux correlation expected from fluorescence emission along the line of sight. However, the observed iron line flux is slightly higher, indicating the possibility of a higher iron abundance or the presence of non-uniform material. We argue that the source most likely has only been observed in the subcritical (non-radiation dominated) state since its pulse profile is stable over all observed luminosities and the energy of the CRSF is approximately the same at the highest (∼5 × 10{sup 37} erg s{sup −1}) and lowest (∼5 × 10{sup 36} erg s{sup −1}) observed 3–60 keV luminosities.

  6. Human rhinoviruses induce IL-35-producing Treg via induction of B7-H1 (CD274) and sialoadhesin (CD169) on DC.

    Science.gov (United States)

    Seyerl, Maria; Kirchberger, Stefanie; Majdic, Otto; Seipelt, Joachim; Jindra, Christoph; Schrauf, Catharina; Stöckl, Johannes

    2010-02-01

    IL-35 is a heterodimer of EBV-induced gene 3 and of the p35 subunit of IL-12, and recently identified as an inhibitory cytokine produced by natural Treg in mice, but not in humans. Here we demonstrate that DC activated by human rhinoviruses (R-DC) induce IL-35 production and release, as well as a suppressor function in CD4(+) and CD8(+) T cells derived from human peripheral blood but not in naïve T cells from cord blood. The induction of IL-35-producing T cells by R-DC was FOXP3-independent, but blocking of B7-H1 (CD274) and sialoadhesin (CD169) on R-DC with mAb against both receptors prevented the induction of IL-35. Thus, the combinatorial signal delivered by R-DC to T cells via B7-H1 and sialoadhesin is crucial for the induction of human IL-35(+) Treg. These results demonstrate a novel pathway and its components for the induction of immune-inhibitory T cells.

  7. USING THE ASTM E 274 SKID TRAILER DATA TO CHARACTERIZE PAVEMENT FRICTION BEHAVIOR WITH RESPECT TO THE TRAVELING SPEED AND THE WHEEL SLIP RATIO

    Directory of Open Access Journals (Sweden)

    MADHURA RAJAPAKSHE

    2012-01-01

    Full Text Available Una visión tridimensional de la resistencia al deslizamiento de superficies de pavimento respecto a variables como la velocidad y la razón de deslizamiento permiten caracterizar apropiadamente su comportamiento y facilitan el entendimiento del fenómeno. Sin embargo, los modelos utilizados actualmente para caracterizar la resistencia al deslizamiento solo evalúan un comportamiento bidimensional. La presente investigación utiliza los datos obtenidos por el deslizómetro ASTM E 274 para realizar una caracterización 3D del comportamiento de la resistencia al deslizamiento por medio de la fusión de dos reconocidos modelos bidimensionales de fricción (Modelo de Penn State y el Modelo de Rado. Los resultados de la investigación sugieren que la metodología propuesta presenta apropiados niveles de predicción para ser implementados en sistemas de gestión de infraestructura vial.

  8. Neutron Diffraction Studies of a Class A beta-Lactamase Toho-1 E166A/R274N/R276N Triple Mutant

    Energy Technology Data Exchange (ETDEWEB)

    Blakeley, Matthew P. [Institut Laue-Langevin (ILL); Chen, Yu [ORNL; Afonine, Pavel [Lawrence Berkeley National Laboratory (LBNL)

    2010-01-01

    beta-Lactam antibiotics have been used effectively over several decades against many types of bacterial infectious diseases. However, the most common cause of resistance to the beta-lactam antibiotics is the production of beta-lactamase enzymes that inactivate beta-lactams by rapidly hydrolyzing the amide group of the beta-lactam ring. Specifically, the class A extended-spectrum beta-lactamases (ESBLs) and inhibitor-resistant enzymes arose that were capable of hydrolyzing penicillins and the expanded-spectrum cephalosporins and monobactams in resistant bacteria, which lead to treatment problems in many clinical settings. A more complete understanding of the mechanism of catalysis of these ESBL enzymes will impact current antibiotic drug discovery efforts. Here, we describe the neutron structure of the class A, CTX-M-type ESBL Toho-1 E166A/R274N/R276N triple mutant in its apo form, which is the first reported neutron structure of a beta-lactamase enzyme. This neutron structure clearly reveals the active-site protonation states and hydrogen-bonding network of the apo Toho-1 ESBL prior to substrate binding and subsequent acylation. The protonation states of the active-site residues Ser70, Lys73, Ser130, and Lys234 in this neutron structure are consistent with the prediction of a proton transfer pathway from Lys73 to Ser130 that is likely dependent on the conformation of Lys73, which has been hypothesized to be coupled to the protonation state of Glu166 during the acylation reaction. Thus, this neutron structure is in agreement with a proposed mechanism for acylation that identifies Glu166 as the general base for catalysis.

  9. Intraoperative cardiac arrest during anesthesia:a retrospective study of 218 274 anesthetics undergoing non-cardiac surgery in a US teaching hospital

    Institute of Scientific and Technical Information of China (English)

    AN Jian-xiong; Li-Ming Zhang; Erin A.Sullivan; GUO Qu-lian; John P.Williams

    2011-01-01

    Background Patient safety has been gained much more attention in recent years.The authors reviewed patients who had cardiac arrest in the operating rooms undergoing noncardiac surgery between January 1989 and December 2001 at the University of Pittsburgh Medical Center,USA.The main objectives of the study were to determine the incidence of intraoperative cardiac arrest,to identify possible causes of cardiac arrest and to explore amenable modifications.Methods With approval by the University of Pittsburgh Institutional Review Board,patients experienced cardiac arrest during surgery were retrieved from medical records,surgical operation and anesthesia records and pathological reports by searching the Medical Archival Retrieval System (MARS),a hospital electronic searching system.Cases of cardiac arrest were collected over a period of thirteen years from the Pre byteria University Hospital (PUH),USA.Results We found 23 cases of intraoperative cardiac arrests occurred in 218 274 anesthesia cases (1.1 per 10 000).Fourteen patients (60.8%) died in the operating room,leading to a mortality rate from all causes of 0.64 per 10 000 anesthetics.Immediate overall survival rate after arrest was 39% (9/23).Half of the patients (12/23) were emergency cases with 41% survival rate (5/12).One fourth of the arrests were trauma patients (6/23).Most arrest patients (87%,20/23) were American Society of Anesthesiologists Physical Status (ASA PS) Ⅳ and Ⅴ,while only three patients were ASA PS-Ⅰ,Ⅱ and Ⅲ,respectively.One case was attributable to an anesthesia-related cardiac arrest and recovered after successful resuscitation.Conclusions Most intraoperative cardiac arrests were not due to anesthesia-related causes.Anesthesia-related cardiac arrests might have a higher survival rate when compared to other possible causes of cardiac arrest in the operating room.

  10. Controle de infecção em cirurgia geral: resultado de um estudo prospectivo de 23 anos e 42.274 cirurgias

    Directory of Open Access Journals (Sweden)

    Edmundo Machado Ferraz

    Full Text Available OBJETIVO: O objetivo deste trabalho foi de avaliar uma metodologia simples adotada há 23 anos em um hospital público universitário no controle das infecções pós-cirúrgicas. MÉTODO: A casuística estudada compreende um total de 42.274 cirurgias realizadas no Serviço de Cirurgia Geral do Hospital das Clínicas da Universidade Federal de Pernambuco (UFPE (janeiro de 1977 a dezembro de 1999. Os dados foram obtidos através um sistema de busca ativa de infecção e de um sistema de vigilância epidemiológica de seguimento pós-operatório, no ambulatório de egressos. A Comissão de Controle de Infecção Hospitalar (CCIH do Hospital das Clínicas (HC da UFPE concentrou sua atuação na prevenção, dando ênfase ao: diagnóstico preciso dos casos de infecção; higiene corporal; controle das afecções associadas; internamento pré-operatório; cuidados com tricotomia; anti-sepsia e assepsia; técnica cirúrgica adequada; divulgação dos resultados e da relação infecção/cirurgião/anestesista e rigoroso controle de antimicrobianos. RESULTADOS: A taxa de infecção de ferida passou de índices em torno de 15-20% para os atuais 7,7%. A infecção urinária foi reduzida de 18,2% para 0,4%, e a infecção respiratória de 22,9% para 2,7%. A mortalidade em decorrência de infecção foi reduzida de 2,8% para os atuais 0,9% e a taxa de infecção de ferida em cirurgia limpa de 12,8% para 3,4%. Na cirurgia ambulatorial, das 27.580 operações a taxa de infecção de ferida foi de 0,4% e a mortalidade de 0,007%. CONCLUSÃO: O que tentamos comprovar com a divulgação de nossos resultados é que controle de infecção se faz com decisão política, força de vontade e motivação em controlar o problema da infecção hospitalar.

  11. The origin of the ∼274 cm{sup −1} additional Raman mode induced by the incorporation of N dopants and a feasible route to achieve p-type ZnO:N thin films

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Ping [Key Laborat of Optoelectronic Functional Materials, College of Physics and Electronic Engineering, Chongqing Normal University, Chongqing 401331 (China); Kong, Chunyang, E-mail: kchy@163.com [Key Laborat of Optoelectronic Functional Materials, College of Physics and Electronic Engineering, Chongqing Normal University, Chongqing 401331 (China); Li, Wanjun, E-mail: liwj13@163.com [Key Laborat of Optoelectronic Functional Materials, College of Physics and Electronic Engineering, Chongqing Normal University, Chongqing 401331 (China); College of Physics, Chongqing University, Chongqing 401331 (China); Qin, Guoping [Key Laborat of Optoelectronic Functional Materials, College of Physics and Electronic Engineering, Chongqing Normal University, Chongqing 401331 (China); College of Physics, Chongqing University, Chongqing 401331 (China); Xu, Qing; Zhang, Hong [Key Laborat of Optoelectronic Functional Materials, College of Physics and Electronic Engineering, Chongqing Normal University, Chongqing 401331 (China); Ruan, Haibo [Research Center for Materials Interdisciplinary Sciences, Chongqing University of Arts and Sciences, Chongqing 402160 (China); Cui, Yuting [Key Laborat of Optoelectronic Functional Materials, College of Physics and Electronic Engineering, Chongqing Normal University, Chongqing 401331 (China); Fang, Liang [College of Physics, Chongqing University, Chongqing 401331 (China)

    2015-02-01

    Highlights: • ZnO:N films were grown on quartz substrates by RF magnetron sputtering technique. • ZnO:N thin films exhibit anomalous variation of ∼274 cm{sup −1} Raman mode. • The origin of the ∼274 cm{sup −1} mode induced by N dopants is Zn{sub i}-related defects. • Choosing appropriate N{sub 2} flow rate and annealing are the key to achieve p-type ZnO:N. - Abstract: Nitrogen doped ZnO films (ZnO:N) were deposited on quartz glass substrates by radio-frequency magnetron sputtering technique with various N{sub 2} flow rate mixed with Ar. Raman measurements indicate that the intensity of ∼274 cm{sup −1} mode of ZnO:N films exhibits an anomalous variation, which neither depends on N{sub 2} flow rate nor on N{sub O} acceptor content based on X-ray photoelectron spectroscopy (XPS) analysis. Combined with defect formation energy calculations, it is demonstrated that the ∼274 cm{sup −1} mode is attributed to Zn{sub i} defects which can be increased by the incorporation of N{sub O} acceptors, but suppressed by the presence of (N{sub 2}){sub O} double donors. XPS and optical absorption spectra suggest that ZnO:N film prepared under specific N{sub 2} flow rate (Ar:N{sub 2} = 3:1), has high concentration of acceptor N{sub O} with shallow states and the absence of shallow donor (N{sub 2}){sub O} defects, could be most likely to achieve p-type conductivity. But, at the same time, such specific ZnO:N film is the presence of shallow donor Zn{sub i} defects bonded with N{sub O} acceptors. Performing density functional calculations in conjunction with the climbing image nudged elastic band method shows that Zn{sub i} could be dissociated from Zn{sub i}–N{sub O} complexes by post-annealing treatment and N{sub O} acceptors would be activated to p-type ZnO:N. This is confirmed by our further Hall investigation, indicating that p-type ZnO:N can be achieved by choosing appropriate post-annealing treatment.

  12. Controle de infecção em cirurgia geral: resultado de um estudo prospectivo de 23 anos e 42.274 cirurgias Infection control in general surgery: results of a prospective study in 42,274 surgeries during 23 years

    Directory of Open Access Journals (Sweden)

    Edmundo Machado Ferraz

    2001-02-01

    Full Text Available OBJETIVO: O objetivo deste trabalho foi de avaliar uma metodologia simples adotada há 23 anos em um hospital público universitário no controle das infecções pós-cirúrgicas. MÉTODO: A casuística estudada compreende um total de 42.274 cirurgias realizadas no Serviço de Cirurgia Geral do Hospital das Clínicas da Universidade Federal de Pernambuco (UFPE (janeiro de 1977 a dezembro de 1999. Os dados foram obtidos através um sistema de busca ativa de infecção e de um sistema de vigilância epidemiológica de seguimento pós-operatório, no ambulatório de egressos. A Comissão de Controle de Infecção Hospitalar (CCIH do Hospital das Clínicas (HC da UFPE concentrou sua atuação na prevenção, dando ênfase ao: diagnóstico preciso dos casos de infecção; higiene corporal; controle das afecções associadas; internamento pré-operatório; cuidados com tricotomia; anti-sepsia e assepsia; técnica cirúrgica adequada; divulgação dos resultados e da relação infecção/cirurgião/anestesista e rigoroso controle de antimicrobianos. RESULTADOS: A taxa de infecção de ferida passou de índices em torno de 15-20% para os atuais 7,7%. A infecção urinária foi reduzida de 18,2% para 0,4%, e a infecção respiratória de 22,9% para 2,7%. A mortalidade em decorrência de infecção foi reduzida de 2,8% para os atuais 0,9% e a taxa de infecção de ferida em cirurgia limpa de 12,8% para 3,4%. Na cirurgia ambulatorial, das 27.580 operações a taxa de infecção de ferida foi de 0,4% e a mortalidade de 0,007%. CONCLUSÃO: O que tentamos comprovar com a divulgação de nossos resultados é que controle de infecção se faz com decisão política, força de vontade e motivação em controlar o problema da infecção hospitalar.BACKGROUND: The aim of this study was evaluate a methodology during 23 years in a public hospital used infection for control of surgeries. METHODS: A total of 42,274 surgeries in the General Surgery Division of the

  13. Incidence and causes of lower-limb amputations in the city of Ribeirão Preto from 1985 to 2008: evaluation of the medical records from 3,274 cases

    Directory of Open Access Journals (Sweden)

    Bruna Maria Bueno Barbosa

    Full Text Available ABSTRACT: Objective: It was to identify trends of traumatic and non-traumatic causes of lower limb amputations, as well as the role played by population aging, traffic violence increase, public health policy of diabetes control program and drivers anti-alcohol laws on these amputations. Method: Hospitalization data recorded in the discharge forms of 32 hospitals located in the region of Ribeirão Preto, Brazil, from 1985 to 2008 were analyzed. Result: A total of 3,274 lower-limb amputations were analyzed, of which 95.2% were related to non-traumatic causes, mainly infectious and ischemic complications of diabetes mellitus. Cancer (2.8% and congenital (1.3% causes were included in this group. Only 4.8% were related to traumatic causes. Traumatic amputation average rate was 1.5 amputations in 100,000 habitants with a slight tendency of increase in the last 5 years. Non-traumatic causes showed an average rate of 30.0 amputations for 100,000 habitants and remained relatively constant during the whole period. Non-traumatic were much more predominant in patients older than 60 years and traumatic amputations occurred more frequently in patients younger than 39 years. Conclusion: The overall rates of amputation and the rates of traumatic and non-traumatic amputations remained nearly constant during the study period. The impact of diabetes control policies and the introduction of traffic safety laws could not be identified on the amputation rates.

  14. Densities and volume properties of (water + tert-butanol) over the temperature range of (274.15 to 348.15) K at pressure of 0.1 MPa

    Energy Technology Data Exchange (ETDEWEB)

    Egorov, Gennadiy I., E-mail: gie@isc-ras.r [Laboratory of Structure and Dynamics of Molecular and Ion-Molecular Solutions, Institute of Solution Chemistry, Russian Academy of Sciences, 1 Akademicheskaya Street, 153045 Ivanovo (Russian Federation); Makarov, Dmitriy M. [Laboratory of Structure and Dynamics of Molecular and Ion-Molecular Solutions, Institute of Solution Chemistry, Russian Academy of Sciences, 1 Akademicheskaya Street, 153045 Ivanovo (Russian Federation)

    2011-03-15

    The densities of {l_brace}water (1) + tert-butanol (2){r_brace} binary mixture were measured over the temperature range (274.15 to 348.15) K at atmospheric pressure using 'Anton Paar' digital vibrating-tube densimeter. Density measurements were carried out over the whole concentration range at (308.15 to 348.15) K. The following volume parameters were calculated: excess molar volumes and thermal isobaric expansivities of the mixture, partial molar volumes and partial molar thermal isobaric expansivities of the components. Concentration dependences of excess molar volumes were fitted with Redlich-Kister equation. The results of partial molar volume calculations using four equations were compared. It was established that for low alcohol concentrations at T {<=} 208 K the inflection points at x{sub 2} {approx} 0.02 were observed at concentration dependences of specific volume. The concentration dependences of partial molar volumes of both water and tert-butanol had extremes at low alcohol content. The temperature dependence of partial molar volumes of water had some inversion at x{sub 2} {approx} 0.65. The temperature dependence of partial molar volumes of tert-butanol at infinite dilution had minimum at {approx}288 K. It was discovered that concentration dependences of thermal isobaric expansivities of the mixture at small alcohol content and low temperatures passed through minimum.

  15. Reference: 274 [Arabidopsis Phenome Database[Archive

    Lifescience Database Archive (English)

    Full Text Available adimir et al. 2005 Oct. Plant Cell 17(10):2723-37. The 26S proteasome plays a central role in the degradatio...n of regulatory proteins involved in a variety of developmental processes. It consists of two multisubunit p...otoderm, and procambium. Cyclin B1 protein was not degraded in these embryos, consistent with cell division ...defects. Double mutant plants (rpn1a/RPN1a rpn1b/rpn1b) produced embryos with a p...23-37 16169895 2005 Oct The Plant cell Brukhin Vladimir|Gagliardini Valeria|Genschik Pascal|Gheyselinck Jacqueline|Grossniklaus Ueli

  16. BDML Metadata: 274 [SSBD[Archive

    Lifescience Database Archive (English)

    Full Text Available Ce_KK_P002 BDML file for quantitative information about nuclear division dynamics o...f wild-type embryo quantitative information about nuclear division dynamics in wild-type embryo C. elegans nuclear division dynamic

  17. 33 CFR 274.3 - References.

    Science.gov (United States)

    2010-07-01

    ..., Occupational Safety and Health Act of 1970 (84 Stat. 1609, 29 U.S.C. 668) 29 December 1970. (c) Medical Surveillance Guide, U.S. Army Environmental Hygiene Agency, January 1975. (d) Guide for the Medical Surveillance of Pest Controllers, U.S. Army Environmental Hygiene Agency, March 1976, as amended. (e) Pesticide...

  18. 21 CFR 558.274 - Hygromycin B.

    Science.gov (United States)

    2010-04-01

    ... (airsac infection), blue comb (nonspecific infectious enteritis) As bacitracin methylene disalicylate or... infection), blue comb (nonspecific infectious enteritis) Feed containing not less than 25% of penicillin... respiratory disease (airsac infection), blue comb (nonspecific infectious enteritis) Combination...

  19. 50 CFR 216.274 - Mitigation.

    Science.gov (United States)

    2010-10-01

    .... (NAVEDTRA 12968-D). (G) While in transit, naval vessels shall be alert at all times, use extreme caution... direction and are dictated by environmental and other conditions (e.g., safety, weather). (I) Floating weeds..., personnel shall utilize all available sensor and optical systems (such as night vision goggles) to aid in...

  20. QTL Information Table: 274 [Q-TARO

    Lifescience Database Archive (English)

    Full Text Available qPEN-4 Morphological trait Panicle/flower Panicle exsertion RFLP C)Interval DHL IR6....P., and Khush, G.S. (2002). Molecular mapping of quantitative trait loci for plant growth, yield and yield related trait

  1. 7 CFR 1822.274 - Loan closing.

    Science.gov (United States)

    2010-01-01

    ... PRIMARILY FOR REAL ESTATE PURPOSES RURAL HOUSING LOANS AND GRANTS Rural Housing Site Loan Policies... Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS-COOPERATIVE... the OGC determines the Form to be inappropriate, real estate mortgage Form FmHA or its...

  2. 26 CFR 1.274-5T - Substantiation requirements (temporary).

    Science.gov (United States)

    2010-04-01

    ... device with the aid of a logging program will constitute an adequate record. (D) Confidential information...) specifically designed and used to carry heavy tools, testing equipment, or parts if— (i) The shelves, racks,...

  3. 49 CFR 178.274 - Specifications for UN portable tanks.

    Science.gov (United States)

    2010-10-01

    ... from a fire (see § 178.275(g)). Jacket means the outer insulation cover or cladding which may be part... attachments and supports between the shell and jacket, provided their material properties at the minimum and... loads through the expected life of the portable tank. (2) Portable tank shells, fittings, and pipework...

  4. 77 FR 274 - Combined Notice of Filings #1

    Science.gov (United States)

    2012-01-04

    ...: ER12-670-000. Applicants: Rhode Island LFG Genco LLC. Description: Rhode Island LFG Genco LLC MBR... p.m. ET 1/12/12. Docket Numbers: ER12-674-000. Applicants: Rhode Island Engine Genco LLC. Description: Rhode Island Engine Genco LLC MBR Tariff to be effective 2/20/2012. Filed Date:...

  5. 40 CFR 180.274 - Propanil; tolerances for residues.

    Science.gov (United States)

    2010-07-01

    ....05 Horse, meat byproducts 1.0 Milk 0.05 Poultry, fat 0.05 Poultry, meat 0.10 Poultry, meat byproducts 0.50 Rice, bran 40 Rice, grain 10 Rice, hulls 30 Rice, straw 75 Sheep, fat 0.10 Sheep, meat 0.05 Sheep, meat byproducts 1.0 (b) Section 18 emergency exemptions. (c) Tolerances with...

  6. 1935 15' Quad #274 Aerial Photo Mosaic Index

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — Aerial Photo Reference Mosaics contain aerial photographs that are retrievable on a frame by frame basis. The inventory contains imagery from various sources that...

  7. Dicty_cDB: CFH274 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available ry Canis familiaris genomic, genomic survey sequence. 40 0.11 2 BQ507132 |BQ507132.2 EST614547 Generation of...sequence, mRNA sequence. 42 0.33 2 BQ507131 |BQ507131.1 EST614546 Generation of a set of potato cDNA clones

  8. 47 CFR 27.4 - Terms and definitions.

    Science.gov (United States)

    2010-10-01

    ... Purpose Bankruptcy Remote Entity that is formed to build and operate the shared wireless broadband network... interoperable wireless broadband network operating on the 758-763 MHz and 788-793 MHz bands and the 763-768 MHz... of Commerce) Network Assets Holder. The Network Assets Holder is a Special Purpose Bankruptcy...

  9. 40 CFR 52.274 - California air pollution emergency plan.

    Science.gov (United States)

    2010-07-01

    ..., and welfare. (ii) Shift oil burning power generation to combined cycle gas turbine generating... of car pools or otherwise reduce employee motor vehicle travel. (H) For stage 2 and 3 episodes, the...

  10. Dicty_cDB: SLF274 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available 5215 |pid:none) Lymphocytic choriomeningitis virus... 39 0.20 AE014187_324( AE014187 |pid:none) Plasmodium f...alciparum 3D7 chromo... 37 0.75 EU480452_2( EU480452 |pid:none) Lymphocytic choriomeningitis... virus... 36 1.3 AF325214_2( AF325214 |pid:none) Lymphocytic choriomeningitis virus... 36 1.7 ( P...09992 ) RecName: Full=Nucleoprotein; AltName: Full=Nucleocapsid... 35 2.2 Y16308_1( Y16308 |pid:none) Lymphocytic choriomeningitis

  11. Command and Control Career Ladder, AFSC 274X0.

    Science.gov (United States)

    1987-04-01

    OPERATIONAL SECURITY (OPSEC) RULES 77 E176 REPRODUCE UNCLASSIFIED DOCUMENTS 77 F307 PROVIDE SECURITY FOR CLASSIFIED MATERIALS OR EQUIPMENT 76 E175 REPRODUCE...CLASSIFIED SECRET AND TOP SECRET 77 C96 REVIEW INSPECTION AND OPERATIONAL REPORTS 76 E176 REPRODUCE UNCLASSIFIED DOCUMENTS 76 E175 REPRODUCE CLASSIFIED...PARTICIPATE IN CONFERENCES OR POLICY MEETINGS 100 B56 DRAFT CORRESPONDENCE OR REPORTS 97 E176 REPRODUCE UNCLASSIFIED DOCUMENTS 86 B55 DRAFT CHANGES TO MANUALS

  12. Dicty_cDB: SLC274 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available VTDKTITPFDLETDLREVLVDDEVV SKVHNLIFGVGLPVIKSVELIAGDDDNNDMVTPNGDDILPPTSDIKTYYFEKLIGKSESS KPLIIN*nyliffk*nkikkqik*tkkvckgkkkinaim...FDLETDLREVLVDDEVV SKVHNLIFGVGLPVIKSVELIAGDDDNNDMVTPNGDDILPPTSDIKTYYFEKLIGKSESS KPLIIN*nyliffk*nkikkqik*tkkvckgkkkinaim

  13. Dicty_cDB: VSH274 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available otein 6; Flags: Prec... 36 1.3 EF025354_1( EF025354 |pid:none) Synthetic construct multivalent an... 35 2.3 ...ivalent an... 35 2.3 EF025355_1( EF025355 |pid:none) Synthetic construct multival...( P27591 ) RecName: Full=23 kDa integral membrane protein; AltName... 35 2.3 EF025352_1( EF025352 |pid:none) Synthetic construct mult...ent an... 35 2.3 protein update 2009. 3.23 PSORT psg: 0.75 gvh: 0.57 alm: 0.12 top:

  14. Elementary Statistics I--Mathematics 274 Course Syllabus, Fall 2001.

    Science.gov (United States)

    Clark, Deborah L.

    This document features the syllabus for a course in Elementary Statistics/Mathematics at Southern University in Baton Rouge, LA. The course textbook, a course description, readings, goals, and course requirements are presented. Basic descriptive analysis and mathematical concepts commonly used in statistics are emphasized in the course. Topics…

  15. Worldwide Report Telecommunications Policy, Research and Development No. 274.

    Science.gov (United States)

    2007-11-02

    Text] [Lima EL COMERCIO in Spanish 27 Apr 83 p 3] 8143 CSO: 5500/2071 ARGENTINA BRIEFS SATELLITE GROUND STATION—Buenos Aires, 5 May (TELAM...Iquitos, Arequipa, lea, Huaraz, Cuzco and Tacna. [TextJ [.Lima EL COMERCIO in Spanish 3 May 83 p a 8 PY] CSO; 5500/2074 ST LUCIA DETAILED REVIEW OF

  16. 38 CFR 21.274 - Revolving fund loan.

    Science.gov (United States)

    2010-07-01

    ... continue in a rehabilitation program without such assistance. (b) Definition. The term advance means a non...) VOCATIONAL REHABILITATION AND EDUCATION Vocational Rehabilitation and Employment Under 38 U.S.C. Chapter 31... following conditions are present: (1) An Individualized Written Rehabilitation Plan, Individualized...

  17. 7 CFR 274.6 - Replacement issuances to households.

    Science.gov (United States)

    2010-01-01

    ... recipient's signature on the authorization document matches the signature on the ID card. In a Photo ID area... matches the serial number on the recipient's ID card; (3) Issue a replacement in accordance with... recipient's ID card. Any replacement which results in duplicate participation shall be considered...

  18. 48 CFR 1816.405-274 - Award fee evaluation factors.

    Science.gov (United States)

    2010-10-01

    ... factor, if used, must include consideration of risk management (including mission success, safety... procurement. Normally, technical and schedule considerations will be included in all CPAF contracts as... Procurement (Code HS) shall be notified prior to the determination of a zero award fee because of a...

  19. Dicty_cDB: VFI274 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available 276 e-144 2 AB093510 |AB093510.1 Saccharomyces exiguus VMA1-2 gene for vacuolar membrane ATPase subunit a p...recursor 2, partial cds, strain:IFO1128. 80 2e-32 5 AB093509 |AB093509.1 Saccharomyces exiguus VMA1-1 gene f

  20. Dicty_cDB: AFO274 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available Sequences producing significant alignments: (bits) Value N AC012149 |AC012149.11 Homo sapiens chromosome 3 clone RP11-119E13, WORK...mo sapiens chromosome 3 clone RP11-717C3 map 3, WORKING DRAFT SEQUENCE, 50 unordered pieces. 46 1e-04 2 AC10...6532 |AC106532.4 Rattus norvegicus clone CH230-136K8, WORKING DRAFT SEQUENCE, 1 ordered piece. 50 2e-04 2 AC...50 2e-04 2 AC068766 |AC068766.13 Homo sapiens chromosome 3 clone RP11-84J20, WORK...ING DRAFT SEQUENCE, 58 unordered pieces. 50 2e-04 2 AC140203 |AC140203.1 Mus musculus chromosome UNK clone RP24-334J15, WORK

  1. 7 CFR 274.1 - State agency issuance responsibility.

    Science.gov (United States)

    2010-01-01

    ... perpetual inventory records and the monthly reports of the coupon issuer or bulk storage point. This review... firm with expertise in auditing and accounting. State agencies may use the results of reviews of coupon issuers by independent audit or accounting firms as long as the food coupon issuance operations of...

  2. 37 CFR 2.74 - Form and signature of amendment.

    Science.gov (United States)

    2010-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Form and signature of... signature of amendment. (a) Form of Amendment. Amendments should be set forth clearly and completely... record. (b) Signature. A request for amendment of an application must be signed by the applicant,...

  3. Dicty_cDB: CHM274 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available from Patent WO0168911. 42 0.056 3 BD460584 |BD460584.1 Diagnosis of Diseases Asso...ciated with Cell Cycle. 42 0.056 3 BD452506 |BD452506.1 Diagnosis of Diseases Associated with Cell Cycle. 42

  4. Nanoose Range Current Characteristics at 274m Depth

    Science.gov (United States)

    1977-05-01

    data point is the resultant vector summation of the actual current sampled every 1/8 turn of the Savonius rotor speed sensor over a 112.5-second...E. Woodward and Gerald F. Appel, July 1973 5. NOAA-TM-NOS-NOIC-3, Effects of Vertical Motion on Vector Averaging ( Savonius Rotor) and Electromagnetic...IAVTORPSTh tracking ranges. The measurement apparatus entails’a Hydro Products Savonius rotor and directional vane follower. These sensors are Lpart of the

  5. Dicty_cDB: SHH274 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available e 2 map 6245135-6357017 strain AX4, complete sequence. 42 0.72 5 AF435076 |AF435076.2 Tetrahymena thermophila anlage...n stage induced 1 protein (ASI1) and anlagen stage induced 2 protein (ASI

  6. OC274L01: WHOI cruise 274 leg 01 aboard the R/V Oceanus from 1996-02-01 - 1996-02-24 (NODC Accession 0078920)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Post-cruise download of raw data from shipboard computer(s) as furnished by the Woods Hole Oceanographic Institution Shipboard Scientific Support Group and archived...

  7. Deployment and optimization of biomacromolecule molecular dynamics simulation process on hundred trillion times clusterto 6 720 CPU cores in this task, the total computing speed accumulated to 2 274 ns/d, which offers a new approach to run the molec...%生物大分子的分子动力学模拟过程在百万亿次集群上的部署优化

    Institute of Scientific and Technical Information of China (English)

    潘龙强; 耿存亮; 慕宇光; 刘鑫; 胡毅; 潘景山; 周亚滨; 龚斌; 王禄山

    2012-01-01

    simultaneously used up to 6 720 CPU cores in this task, the total computing speed accumulated to 2 274 ns/d, which offers a new approach to run the molecular dynamics over ten thousand CPU cores.

  8. TLR3 triggering regulates PD-L1 (CD274) expression in human neuroblastoma cells

    NARCIS (Netherlands)

    Boes, Marianne; Meyer-Wentrup, Friederike

    2015-01-01

    Neuroblastoma is the most common extracranial solid tumor in children, causing 12% of all pediatric cancer mortality. Neuroblastoma specific T-cells have been detected in patients, but usually fail to attack and eradicate the tumors. Tumor immune evasion may thus play an important role in neuroblast

  9. 17 CFR 274.128 - Form N-CSR, certified shareholder report.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Form N-CSR, certified... Form N-CSR, certified shareholder report. This form shall be used by registered management investment... of this chapter. Editorial Note: For Federal Register citations affecting Form N-CSR, see the List...

  10. Comparative genomics of 274 Vibrio cholerae genomes reveals mobile functions structuring three niche dimensions

    NARCIS (Netherlands)

    Dutilh, Bas E; Thompson, Cristiane C; Vicente, Ana C P; Marin, Michel A; Lee, Clarence; Silva, Genivaldo G Z; Schmieder, Robert; Andrade, Bruno G N; Chimetto, Luciane; Cuevas, Daniel; Garza, Daniel R; Okeke, Iruka N; Aboderin, Aaron Oladipo; Spangler, Jessica; Ross, Tristen; Dinsdale, Elizabeth A; Thompson, Fabiano L; Harkins, Timothy T; Edwards, Robert A

    2014-01-01

    BACKGROUND: Vibrio cholerae is a globally dispersed pathogen that has evolved with humans for centuries, but also includes non-pathogenic environmental strains. Here, we identify the genomic variability underlying this remarkable persistence across the three major niche dimensions space, time, and h

  11. 8 CFR 274a.2 - Verification of identity and employment authorization.

    Science.gov (United States)

    2010-01-01

    ... regarding his or her absence; (3) The employer's past history of recalling absent employees for employment... personnel, hardware, software, files, indexes, and software documentation. (4) A person or entity who... audit trail is a record showing who has accessed a computer system and the actions performed within or...

  12. 7 CFR 274.12 - Electronic Benefit Transfer issuance system approval standards.

    Science.gov (United States)

    2010-01-01

    ... equipped to accept EBT cards. (viii) Disclosure information regarding adjustments and a household's rights... transmission. Any of the network security measures may be utilized together or separately and may be applied at... acceptance testing. The Department reserves the right to participate in the Functional Demonstration if...

  13. Comparative genomics of 274 Vibrio cholerae genomes reveals mobile functions structuring three niche dimensions

    NARCIS (Netherlands)

    Dutilh, B.E.; Thompson, C.C.; Vicente, A.C.; Marin, M.A.; Lee, C.; Silva, G.G.; Schmieder, R.; Andrade, B.G.; Chimetto, L.; Cuevas, D.; Garza, D.R.; Okeke, I.N.; Aboderin, A.O.; Spangler, J.; Ross, T.; Dinsdale, E.A.; Thompson, F.L.; Harkins, T.T.; Edwards, R.A.

    2014-01-01

    BACKGROUND: Vibrio cholerae is a globally dispersed pathogen that has evolved with humans for centuries, but also includes non-pathogenic environmental strains. Here, we identify the genomic variability underlying this remarkable persistence across the three major niche dimensions space, time, and

  14. 26 CFR 1.274-3 - Disallowance of deduction for gifts.

    Science.gov (United States)

    2010-04-01

    ... reason of the employee's length of service (including an award upon retirement), productivity, or safety... to an employee by reason of the employee's length of service (including retirement), productivity, or... the wife has a bona fide business connection with the taxpayer independently of her relationship...

  15. Histopathologic study on muscle diseases among Koreans (274 muscle biopsy analysis).

    OpenAIRE

    Chi, J. G.; Koo, H S; Roh, J K

    1989-01-01

    All the diagnostic muscle biopsy cases were collected from the file of Department of Pathology, Seoul National University Hospital during June 1976 to December 1978. Slides were reviewed and correlated with clinical informations. Two hundred seventy four cases showed pathological changes, which were classified into six large groups (Table 1). Neurogenic atrophy was most common, 97 cases (35%), including 71 cases of motor neuron disease and 22 cases of peripheral neuropathy. Muscular dystrophy...

  16. EVIDENCE FOR COLD ACCRETION: PRIMITIVE GAS FLOWING ONTO A GALAXY AT z {approx} 0.274

    Energy Technology Data Exchange (ETDEWEB)

    Ribaudo, Joseph; Lehner, Nicolas; Christopher Howk, J. [Department of Physics, University of Notre Dame, Notre Dame, IN 46556 (United States); Werk, Jessica K.; Xavier Prochaska, J. [UCO/Lick Observatory, University of California at Santa Cruz, Santa Cruz, CA 95064 (United States); Tripp, Todd M.; Meiring, Joseph D. [Department of Astronomy, University of Massachusetts, Amherst, MA 01003 (United States); Tumlinson, Jason [Space Telescope Science Institute, Baltimore, MD 21218 (United States)

    2011-12-20

    We present UV and optical observations from the Cosmic Origins Spectrograph on the Hubble Space Telescope and Keck of a z = 0.27395 Lyman limit system (LLS) seen in absorption against the QSO PG1630+377. We detect H I absorption with log N(H I) = 17.06 {+-} 0.05 as well as Mg II, C III, Si III, and O VI in this system. The column densities are readily explained if this is a multi-phase system, with the intermediate and low ions arising in a very low metallicity ([Mg/H] = -1.71 {+-} 0.06) photoionized gas. We identify via Keck spectroscopy and Large Binocular Telescope imaging a 0.3 L{sub *} star-forming galaxy projected 37 kpc from the QSO at nearly identical redshift (z = 0.27406 and {Delta}v = -26 km s{sup -1}) with near solar metallicity ([O/H] = -0.20 {+-} 0.15). The presence of very low metallicity gas in the proximity of a near-solar metallicity, sub-L{sub *} galaxy strongly suggests that the LLS probes gas infalling onto the galaxy. A search of the literature reveals that such low-metallicity LLSs are not uncommon. We found that 50% (4/8) of the well-studied z {approx}< 1 LLSs have metallicities similar to the present system and show sub-L{sub *} galaxies with {rho} < 100 kpc in those fields where redshifts have been surveyed. We argue that the properties of these primitive LLSs and their host galaxies are consistent with those of cold mode accretion streams seen in galaxy simulations.

  17. 26 CFR 1.274-4 - Disallowance of certain foreign travel expenses.

    Science.gov (United States)

    2010-04-01

    ... paragraph (d) of this section) constitutes 25 percent or more of the total time on such travel. (c) Travel... percent or more of travel time under paragraph (d) of this section and for purposes of allocating expenses... percent or more of travel time—(1) In general. This section does not apply to any expense of...

  18. Regulation of the histone acetyltransferase activity of hMOF via autoacetylation of Lys274

    Institute of Scientific and Technical Information of China (English)

    Bingfa Sun; Shunling Guo; Qingyu Tang; Chen Li; Rong Zeng; Zhiqi Xiong; Chen Zhong; Jianping Ding

    2011-01-01

    Dear Editor, Males-absent-on-the-first (MOF, also called MYST1 or KAT8) is a histone acetyltransferase (HAT) belonging to the MOZ, Ybf2/Sas3, Sas2 and Tip60 (MYST) family.MOF has been shown to possess a specific HAT activity towards Lysl6 of histone H4 (H4K16) [1].Homozygous knockout of MOF in mice results in loss of H4K16 acetylation and embryonic lethality, indicating that MOF and H4K16 acetylation are essential for embryogenesis and genome stability in mammals [2].Downregulation of human MOF (hMOF) leads to dramatic nuclear morphological deformation and inhibition of cell cycle progression [3], and has recently been correlated with primary breast carcinoma and medulloblastoma [4].

  19. 7 CFR 274.10 - Use of identification cards and redemption of coupons by eligible households.

    Science.gov (United States)

    2010-01-01

    ... at communal dining facilities authorized by FNS for that purpose. Any household eligible for and interested in using communal dining facilities in those States or project areas where restaurants are... out-of-office interviews as specified in § 273.2(e)(2). However, the State agency shall replace...

  20. 47 CFR 25.274 - Procedures to be followed in the event of harmful interference.

    Science.gov (United States)

    2010-10-01

    ... local terrestrial source. (c) After the earth station operator has determined that the source of the... in the satellite operator's system, the control center operator shall advise the offending earth...

  1. SU-E-T-274: Does Atmospheric Oxygen Affect the PRESAGE Dosimeter?

    Energy Technology Data Exchange (ETDEWEB)

    Alqathami, M; Ibbott, G [UT MD Anderson Cancer Center, Houston, TX (United States); Blencowe, A [The University of South Australia, South Australia, SA (Australia)

    2015-06-15

    Purpose: To experimentally determine the influence of atmospheric oxygen on the efficiency of the PRESAGE dosimeter and its reporting system. Methods: Batches of the reporting system – a mixture of chloroform and leuchomalachite green dye – and PRESAGE were prepared in aerobic and anaerobic conditions. For anaerobic batches, samples were deoxygenated by bubbling nitrogen through the dosimeter precursors or reporting system for 10 min. The dosimeters and reporting systems were prepared in spectrophotometric cuvettes and glass vials, respectively, and were irradiated with 6 MV photons to various radiation doses using a clinical linear accelerator. Changes in optical density of the dosimeters and reporting system before and after irradiation were measured using a spectrophotometer. In addition, the concentrations of dissolved oxygen were measured using a dissolved oxygen meter. Results: The experiments revealed that oxygen has little influence on the characteristics of PRESAGE, with the radical initiator oxidizing the leucomalachite green even in the presence of oxygen. However, deoxygenation of the reporting system leads to an increase in sensitivity to radiation dose by ∼ 30% when compared to the non-deoxygenated system. A slight improvement in sensitivity (∼ 5%) was also achieved by deoxygenating the PRESAGE precursor prior to casting. Measurement of the dissolved oxygen revealed low levels (0.4 ppm) in the polyurethane precursor used to fabricate the dosimeters, as compared to water (8.6 ppm). In addition, deoxygenation had no effect on the retention of the post-response absorption value of the PRESAGE dosimeter. Conclusion: The results suggest that the presence of oxygen does not inhibit the radiochromic properties of the PRESAGE system. In addition, there were no observed changes in the dose linearity, absorption spectrum and post-response photofading characteristics of the PRESAGE under the conditions investigated.

  2. 17 CFR 274.11d - Form N-6, registration statement of separate accounts organized as unit investment trusts that...

    Science.gov (United States)

    2010-04-01

    ... variable life insurance policies. Form N-6 shall be used as the registration statement to be filed pursuant... statement of separate accounts organized as unit investment trusts that offer variable life insurance... insurance policies to register as unit investment trusts. This form shall also be used for...

  3. 274. Indicaciones de la válvula aórtica ats 3f enable® sin sutura

    Directory of Open Access Journals (Sweden)

    J. Rodríguez-Roda

    2012-04-01

    Conclusiones: La prótesis 3f Enable® presenta un excelente comportamiento hemodinámico en pacientes con anillo aórtico pequeño y con un IMC igual o superior a 30 y consiguiente riesgo de mismatch. La estenosis protésica de 19 mm también se podría considerar como indicación de implante de esta válvula.

  4. El mito del Político (268 D-274 E y la historia de las religiones

    Directory of Open Access Journals (Sweden)

    Giovanni Casadio

    1996-06-01

    Full Text Available The importance of a religious-historical approach for an appropriate understanding of the myth in Plato's Statesman has not been sufficiently emphasized yet. The myth substantially describes the life of the world as two revolutions of the same circle, the ane forward and the ather backward. In the forward revolution God accompanies the world; during the latter he remains in his watch-tower. Within the framework of this myth, which establishes the current philosophical doctrine of the alternating world-periods, we find more or less developed allusions to other well-known themes of the Greek lore: the Golden age, the kingdom of Cronus, the Earth-born Men (gegeneis ... My aim is to reassess the specificity of this Platonic mythopoeia setting it in the general context of ancient religion. In the first part I characterize the motif of the absence of God against the background of the phenomenological -and historical- category of the deus otiosus (with examples derived from the middle-Platonic and gnostic domains. In the second part 1 consider the problem of the source (or sources of evil: apparently the corporeal principle (τὸ σωματοειδές, more properly the state of precosmical chaos. Finally, the question is raised of Plato's dualism in this context: whether radical or mitigated.

  5. 77 FR 28588 - Proposed Priorities-American Overseas Research Centers Program; CFDA Number 84.274A

    Science.gov (United States)

    2012-05-15

    ... research that is vital to understanding the history, culture, economy, languages, and other issues related... learning communities provides an important cultural context that bolsters teaching and research that... collaborations via conferences, teaching opportunities for visiting faculty, and information-sharing through...

  6. Monedas de Guerra y triunfo de Octaviano. Las series CAESAR DIVI F e IMP CAESAR (RIC I 250 - 274)

    OpenAIRE

    2015-01-01

    En 2014 hemos celebrado el bimilenario de la muerte de Augusto, uno de los personajes más destacados del mundo antiguo. Su política y su moral supusieron un importante cambio para el Estado Romano, gracias en parte a su magistral uso de la propaganda política. Octaviano, desde que su tío-abuelo le convirtiera en su heredero, hizo buen uso de la manipulación pública para conseguir sus fines durante el triunvirato y el conflicto posterior. Presentamos una recopilación de su propaganda política ...

  7. Corrigendum to "The physical mechanism of "inhomogeneous; magnetization transfer MRI; [J. Magn. Reson. 274 (2017) 125-136

    Science.gov (United States)

    Manning, Alan P.; Chang, Kimberley L.; MacKay, Alex L.; Michal, Carl A.

    2017-09-01

    The authors regret that in Section 2.1.2, where the inhomogeneous magnetization transfer ratio (ihMTR) of a spin-1 system was considered, one important characteristic of the excitation under selective irradiation was neglected.

  8. 26 CFR 1.274-2 - Disallowance of deductions for certain expenses for entertainment, amusement, recreation, or travel.

    Science.gov (United States)

    2010-04-01

    .... For the disallowance of deductions for the cost of admission to a dinner or program any part of the... the taxpayer or the taxpayer's family. The term entertainment may include an activity, the cost of which is claimed as a business expense by the taxpayer, which satisfies the personal, living, or family...

  9. Nuclear Technology. Course 27: Metrology. Module 27-4, Angle Measurement Instruments, Optical Projections and Surface Texture Gages.

    Science.gov (United States)

    Selleck, Ben; Espy, John

    This fourth in a series of eight modules for a course titled Metrology describes the universal bevel protractor and the sine bar, the engineering microscope and optical projector, and several types of surface texture gages. The module follows a typical format that includes the following sections: (1) introduction, (2) module prerequisites, (3)…

  10. SU-E-J-274: Responses of Medulloblastoma Cells to Radiation Dosimetric Parameters in Intensity-Modulated Radiation Therapy

    Energy Technology Data Exchange (ETDEWEB)

    Park, J [Dept. of Pediatrics, Stanford University School of Medicine, Stanford, CA (United States); Molecular Imaging Program at Stanford, Stanford, CA (United States); Bio-X Program, Stanford, CA (United States); Research Institute of Biomedical Engineering, The Catholic University of Korea, Seoul (Korea, Republic of); Park, J [Proton Therapy Center, National Cancer Center, Goyang (Korea, Republic of); Rogalla, S; Contag, C [Dept. of Pediatrics, Stanford University School of Medicine, Stanford, CA (United States); Molecular Imaging Program at Stanford, Stanford, CA (United States); Bio-X Program, Stanford, CA (United States); Woo, D [Asan Institute for Life Sciences, Asan Medical Center, Seoul (Korea, Republic of); Lee, D [Research Institute of Biomedical Engineering, The Catholic University of Korea, Seoul (Korea, Republic of); Asan Institute for Life Sciences, Asan Medical Center, Seoul (Korea, Republic of); Park, H [Dept. of Radiation Oncology, Ajou University School of Medicine, Suwon (Korea, Republic of); Suh, T [Research Institute of Biomedical Engineering, The Catholic University of Korea, Seoul (Korea, Republic of); Dept. of Biomedical Engineering, The Catholic University of Korea, Seoul (Korea, Republic of)

    2015-06-15

    Purpose: To evaluate radiation responses of the medulloblastoma cell line Daoy in intensity-modulated radiation therapy (IMRT), quantitative variations to variable radiation dosimetic parameters were tracked by bioluminescent images (BLIs). Methods: The luciferase and green fluorescent protein positive Daoy cells were cultured on dishes. The medulloblastoma cells irradiated to different dose rate, interval of fractionated doses, field margin and misalignment, and dose uniformity in IMRT were monitored using bioluminescent images. The cultured cells were placed into a dedicated acrylic phantom to deliver intensity-modulated fluences and calculate accurate predicted dose distribution. The radiation with dose rate from 0.5 Gy/min to 15 Gy/min was irradiated by adjusting monitor unit per minute and source-to-surface distances. The intervals of fractionated dose delivery were changed considering the repair time of double strand breaks (DSB) revealed by straining of gamma-H2AX.The effect of non-uniform doses on the cells were visualized by registering dose distributions and BLIs. The viability according to dosimetric parameters was correlated with bioluminescent intensities for cross-check of radiation responses. Results: The DSB and cell responses due to the first fractionated dose delivery significantly affected final tumor control rather than other parameters. The missing tumor volumes due to the smaller field margin than the tumor periphery or field misalignment caused relapse of cell responses on BLIs. The dose rate and gradient had effect on initial responses but could not bring out the distinguishable killing effect on cancer cells. Conclusion: Visualized and quantified bioluminescent images were useful to correlate the dose distributions with spatial radiation effects on cells. This would derive the effective combination of dose delivery parameters and fractionation. Radiation responses in particular IMRT configuration could be reflected to image based-dose re-optimization.

  11. 76 FR 9320 - Foreign-Trade Zone 274-Butte-Silver Bow, MT; Application for Manufacturing Authority REC Silicon...

    Science.gov (United States)

    2011-02-17

    ... Authority REC Silicon (Polysilicon and Silane Gas) Butte, MT An application has been submitted to the..., requesting manufacturing authority on behalf of REC Silicon, located in Butte, Montana. The application was... regulations of the Board (15 CFR part 400). It was formally filed on February 11, 2011. The REC...

  12. NUCLEAR CHEMISTRY: Element 107 Leaves the Table Unturned.

    Science.gov (United States)

    Service, R F

    2000-08-25

    This week, an international team of chemists reported on the first successful analysis of the chemical properties of bohrium, element 107. The results matched predictions, postponing scientists' hopes of seeing interesting deviations from theory among ultraheavy elements.

  13. 17 CFR 274.303 - Form N-27I-2, notice of withdrawal right and statement of charges for variable life insurance...

    Science.gov (United States)

    2010-04-01

    ... withdrawal right and statement of charges for variable life insurance contractholders required pursuant to... variable life insurance contractholders required pursuant to Rule 6e-2 (§ 270.6e-2 of this chapter). Editorial Note: For Federal Register citations affecting Form N-27I-2, see the List of CFR Sections...

  14. MAS promoter regulation: a role for Sry and tyrosine nitration of the KRAB domain of ZNF274 as a feedback mechanism.

    Science.gov (United States)

    Prokop, Jeremy W; Rauscher, Frank J; Peng, Hongzhuang; Liu, Yuanjie; Araujo, Fabiano C; Watanabe, Ingrid; Reis, Fernando M; Milsted, Amy

    2014-05-01

    The ACE2 (angiotensin-converting enzyme 2)/Ang-(1-7) [angiotensin-(1-7)]/MAS axis of the RAS (renin-angiotensin system) has emerged as a pathway of interest in treating both cardiovascular disorders and cancer. The MAS protein is known to bind to and be activated by Ang-(1-7); however, the mechanisms of this activation are just starting to be understood. Although there are strong biochemical data regarding the regulation and activation of the AT1R (angiotensin II type 1 receptor) and the AT2R (angiotensin II type 2 receptor), with models of how AngII (angiotensin II) binds each receptor, fewer studies have characterized MAS. In the present study, we characterize the MAS promoter and provide a potential feedback mechanism that could compensate for MAS degradation following activation by Ang-(1-7). Analysis of ENCODE data for the MAS promoter revealed potential epigenetic control by KRAB (Krüppel-associated box)/KAP-1 (KRAB-associated protein-1). A proximal promoter construct for the MAS gene was repressed by the SOX [SRY (sex-determining region on the Y chromosome) box] proteins SRY, SOX2, SOX3 and SOX14, of which SRY is known to interact with the KRAB domain. The KRAB-KAP-1 complex can be tyrosine-nitrated, causing the dissociation of the KAP-1 protein and thus a potential loss of epigenetic control. Activation of MAS can lead to an increase in nitric oxide, suggesting a feedback mechanism for MAS on its own promoter. The results of the present study provide a more complete view of MAS regulation and, for the first time, suggest biochemical outcomes for nitration of the KRAB domain.

  15. The AFGL Four Color Infrared Sky Survey: Catalog of Observations at 4. 2, 11.0, 19.8 and 27.4 micrometers

    Science.gov (United States)

    1976-09-17

    Wentworth lnstitute t’nr their coutulhi•Liuns1 to 3 fabrication, Integration, and field support of the payload systems; and Charles Howard, Raymond Wilton...S ’ fabrication, integIration, and field support of the payload systems; and Charles hloward, Raymond Wilton. William Miller, Iban fliscock, and...Neugebauer and Leighton and from an extension of the 2. 2 .m survey (designated by an E) of Neugebauer. 3 The Bright Star number and the Bayer and

  16. CRED Subsurface Temperature Recorder (STR); PRIA, JOH; Long: -169.55502, Lat: 16.71490 (WGS84); Sensor Depth: 2.74m; Data Range: 20080201-20100127.

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Data from Coral Reef Ecosystem Division (CRED), NOAA Pacific Islands Fisheries Science Center (PIFSC) Subsurface Temperature Recorders (STR) provide a time series of...

  17. SU-E-T-274: Radiation Therapy with Very High-Energy Electron (VHEE) Beams in the Presence of Metal Implants

    Energy Technology Data Exchange (ETDEWEB)

    Jensen, C; Palma, B; Qu, B; Maxim, P; Loo, B; Bazalova, M [Department of Radiation Oncology, Stanford University, Stanford, CA (United States); Hardemark, B; Hynning, E [RaySearch Laboratories, Stockholm (Sweden)

    2014-06-01

    Purpose: To evaluate the effect of metal implants on treatment plans for radiation therapy with very high-energy electron (VHEE) beams. Methods: The DOSXYZnrc/BEAMnrc Monte Carlo (MC) codes were used to simulate 50–150MeV VHEE beam dose deposition and its effects on steel and titanium (Ti) heterogeneities in a water phantom. Heterogeneities of thicknesses ranging from 0.5cm to 2cm were placed at 10cm depth. MC was also used to calculate electron and photon spectra generated by the VHEE beams' interaction with metal heterogeneities. The original VMAT patient dose calculation was planned in Eclipse. Patient dose calculations with MC-generated beamlets were planned using a Matlab GUI and research version of RayStation. VHEE MC treatment planning was performed on water-only geometry and water with segmented prostheses (steel and Ti) geometries with 100MeV and 150MeV beams. Results: 100MeV PDD 5cm behind steel/Ti heterogeneity was 51% less than in the water-only phantom. For some cases, dose enhancement lateral to the borders of the phantom increased the dose by up to 22% in steel and 18% in Ti heterogeneities. The dose immediately behind steel heterogeneity decreased by an average of 6%, although for 150MeV, the steel heterogeneity created a 23% increase in dose directly behind it. The average dose immediately behind Ti heterogeneities increased 10%. The prostate VHEE plans resulted in mean dose decrease to the bowel (20%), bladder (7%), and the urethra (5%) compared to the 15MV VMAT plan. The average dose to the body with prosthetic implants was 5% higher than to the body without implants. Conclusion: Based on MC simulations, metallic implants introduce dose perturbations to VHEE beams from lateral scatter and backscatter. However, when performing clinical planning on a prostate case, the use of multiple beams and inverse planning still produces VHEE plans that are dosimetrically superior to photon VMAT plans. BW Loo and P Maxim received research support from RaySearch laboratories; B Hardemark and E Hynning are employees of RaySearch.

  18. Real-time PCR detection and quantification of fish probiotic Phaeobacter strain 27-4 and fish pathogenic Vibrio in microalgae, rotifer, Artemia and first feeding turbot (Psetta maxima) larvae

    DEFF Research Database (Denmark)

    Prol, M.J.; Bruhn, Jesper Bartholin; Pintado, J.

    2009-01-01

    and in presence of microalgae (Isochrysis galbana), rotifers (Brachionus plicatilis), Artemia nauplii or turbot (Psetta maxima) larvae by real-time PCR based on primers directed at genetic loci coding for antagonistic and virulence-related functions respectively. The optimized protocol was used to study...

  19. Discussion on Ubeid, K.A., 2016. Quaternary alluvial deposits of Wadi Gaza in the middle of the Gaza Strip (Palestine): Facies, granulometric characteristics, and their paleoflow direction. JAES 118: 274-283

    Science.gov (United States)

    Roskin, Joel

    2017-10-01

    The location of the Gaza Strip at the southeastern corner of the Mediterranean Sea along a transition zone between Mediterranean and arid climate zones at the meeting point between fluvial, coastal, and aeolian sediments makes the Strip an important region for Quaternary, hydrogeologic, geomorphic, and palaeoclimatic studies (Aish, 2004). Wadi Gaza, the only water course that fully crosses the Gaza Strip into the southeastern Mediterranean Sea is an important water source for the proliferating and dense population of the Gaza Strip (Zaineldeen and Aish, 2012), is an indispensable part of natural life in Gaza and has an interesting history and rich vegetation (Abd Rabou et al., 2016). As such, the hydrogeologic conditions of Wadi Gaza need to be fully resolved. This includes the study of the wadi's palaeohydrology and the current anthropogenic impact upon flow and deposition along the watercourse.

  20. Multibeam collection for TN274: Multibeam data collected aboard Thomas G. Thompson from 2012-01-25 to 2012-02-09, departing from Apra, Guam and returning to Apra, Guam

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set is part of a larger set of data called the Multibeam Bathymetry Database (MBBDB) where other similar data can be found at...

  1. Corrigendum to "Insight into cobalt-doping in Li2FeSiO4 cathode material for lithium-ion battery" [J. Power Sources 274C (2014) 194-202

    Science.gov (United States)

    Zhang, Lu-Lu; Duan, Song; Yang, Xue-Lin; Liang, Gan; Huang, Yun-Hui; Cao, Xing-Zhong; Yang, Jing; Li, Ming; Croft, Mark C.; Lewis, Cale

    2015-03-01

    The authors regret their mistake in that Fig. 2 was misused. The correct Fig. 2 is as follows, and the corresponding description in the second paragraph in Results and discussion part has also been corrected. The changes have been highlighted in bold-italic.

  2. On suitability of present alumina standart YS/T274-1998 and GB/T4294-1997%论氧化铝行业产品标准的适宜性

    Institute of Scientific and Technical Information of China (English)

    李敏; 张明阳

    2001-01-01

    本文根据质量管理的实践经验及销售市场的实际需求,对现行氧化铝行业产品标准从适宜性、质量过剩、标准之间和标准之中的逻辑性和严密性等方面进行了有益的探讨,并着眼国际、国内形势和产品的市场要求,对现行标准提出了修改和完善的建设性意见,并对现行标准中质量过剩问题结合工艺条件、经济效益进行了有益探讨.本文也从中国加入WTO方面提出了修改、完善现行标准的迫切性.

  3. Automatic Parallelization of Scientific Application

    DEFF Research Database (Denmark)

    Blum, Troels

    In my PhD work I show that it is possible to run unmodified Python/NumPy code on modern GPUs. This is done by using the Bohrium runtime system to translate the NumPy array operations into an array based bytecode sequence. Executing these byte-codes on two GPUs from different vendors shows great...... performance gains. Scientists working with computer simulations should be allowed to focus on their field of research and not spend excessive amounts of time learning exotic programming models and languages. We have with Bohrium achieved very promising results by starting out with a relatively simple approach....... This has lead to more specialized methods as I have shown with the work done with both specialized, and parametrizied kernels. Both have their benefits and recognizable use cases. We achieved clear performance benefits without any significant negative impact on overall application performance. Even...

  4. Battling memory requirements of array programming through streaming

    DEFF Research Database (Denmark)

    Kristensen, Mads Ruben Burgdorff; Avery, James Emil; Blum, Troels;

    2016-01-01

    A barrier to efficient array programming, for example in Python/NumPy, is that algorithms written as pure array operations completely without loops, while most efficient on small input, can lead to explosions in memory use. The present paper presents a solution to this problem using array streaming......, implemented in the automatic parallelization high-performance framework Bohrium. This makes it possible to use array programming in Python/NumPy code directly, even when the apparent memory requirement exceeds the machine capacity, since the automatic streaming eliminates the temporary memory overhead...... streaming, yielding corresponding improvements in speed and utilization of GPGPU-cores. The streaming-enabled Bohrium effortlessly runs programs on input sizes much beyond sizes that crash on pure NumPy due to exhausting system memory....

  5. 28 CFR 68.53 - Review of an interlocutory order of an Administrative Law Judge in cases arising under section...

    Science.gov (United States)

    2010-07-01

    ... Administrative Law Judge in cases arising under section 274A or 274C. 68.53 Section 68.53 Judicial Administration... ADMINISTRATIVE LAW JUDGES IN CASES INVOLVING ALLEGATIONS OF UNLAWFUL EMPLOYMENT OF ALIENS, UNFAIR IMMIGRATION... Administrative Law Judge in cases arising under section 274A or 274C. (a) Authority. In a case arising under...

  6. 28 CFR 68.54 - Administrative review of a final order of an Administrative Law Judge in cases arising under...

    Science.gov (United States)

    2010-07-01

    ... an Administrative Law Judge in cases arising under section 274A or 274C. 68.54 Section 68.54 Judicial... BEFORE ADMINISTRATIVE LAW JUDGES IN CASES INVOLVING ALLEGATIONS OF UNLAWFUL EMPLOYMENT OF ALIENS, UNFAIR... an Administrative Law Judge in cases arising under section 274A or 274C. (a) Authority of the Chief...

  7. Reinhard Weipert, Classical Arabic Philology & Poetry. A Bibliographical Handbook of Important Editions from 1960 to 2000/Klassich-Arabische Philologie und Poesie. Eine bibliographisches Handbuch wichtiger Editionen von 1960 bis 2000, Handbook of Oriental Studies/Handbuch der Orientalistik, vol. 63, Leiden-Boston-Köln, Brill, 2002, XII + 274 p.

    Directory of Open Access Journals (Sweden)

    Pierre Larcher

    2004-12-01

    Full Text Available Cet ouvrage se veut un supplément à la fois à la Geschichte der arabischen Literatur (GAL de Carl Brockelmann et à la Geschichte des arabischen Schrifttums (GAS de Fuad Sezgin. Comme on sait, la première remonte maintenant à plus d'un demi-siècle (1943-1949 pour la deuxième édition et même plus de soixante pour le Supplément (1937-1942 et la seconde a l'inconvénient de ne couvrir que la période classique (jusqu'aux alentours de 430H/1038 de la production écrite ancienne en arabe. Certes,...

  8. Gclust Server: 78480 [Gclust Server

    Lifescience Database Archive (English)

    Full Text Available 78480 PoTR_558592 Cluster Sequences Related Sequences(274) 397 eugene3.00050207 1 1...ces Cluster Sequences Link to related sequences Related Sequences(274) Sequence length 397 Representative annotation eugene

  9. 76 FR 76181 - Certain Electronic Paper Towel Dispensing Devices and Components Thereof; Issuance of General...

    Science.gov (United States)

    2011-12-06

    ...,387,274 (``the '274 patent''). The complainant named as respondents Kruger Products LP of Mississauga...Pak Chicago; (2) to redefine ``Kruger'' to ``Kruger Products and/or KTG USA''; (3) to indicate...

  10. Adaptation of Impact Questions from an Existing Toolkit Provided Clear Assessment of Valued Service Elements and Desirable Service Improvements in a Primary Health Care Library and Information Service. A Review of: Urquhart, C., Thomas, R., Ovens, J., Lucking, W., & Villa, J. (2010. Planning changes to health library services on the basis of impact assessment. Health Information and Libraries Journal, 27(4, 277-285. doi: 10.1111/j.1471-1842.2010.00900.x

    Directory of Open Access Journals (Sweden)

    Kate Kelly

    2011-01-01

    Full Text Available Objective – To provide an action plan for the Knowledge, Resource and Information Service (KRIS based on an impact assessment of current services, satisfaction with current services, and views on desirable improvements to service and service delivery.Design – Questionnaire for KRIS service users and interviews with KRIS staff.Setting – Two locations served by KRIS in the north and south of Bristol City in the UK – one a health promotion service and one a National Health Service (NHS teaching hospital.Subjects – A convenience sample of a total of 244 users of the library services at the two locations, 121 users at the health promotion service site and 123 users at the hospital site.Methods – A questionnaire designed for a previous NHS library service impact study was adapted for use with staff other than health workers, since teachers and youth workers, for example, also used the health promotion service. The researchers circulated the questionnaire by mail and email to prospective respondents. The questionnaire asked participants to reflect on the most recent time they had used KRIS services and provide details on the purpose of use, what elements of the service they used, satisfaction with the service or the information provided, the immediate impact on their work, and its probable contribution to future work. It also asked about desirable improvements and how KRIS contributed to the respondents’ work and continuing professional development. The researchers interviewed KRIS staff face to face and asked for their views on the history of the service and future developments.Main Results – The overall response rate was 62.3% (152/244, with similar responses from each site. Community nurses and midwives were the largest group of respondents (n=31, 20.4%, followed by managers and administrators (n=24, 15.8%.Both sites reported health promotion activities as the dominant reason for use. Health promotion leaflets (n=94, 61.8% and resources for loan (n=57, 37.5% were the top two service elements used, with literature searching third (n=46, 30.3%.The service completely met the needs of 93% (n=141 of respondents, with 97.4% (n=148 reporting being wholly satisfied that information was delivered in time.In terms of the immediate cognitive impact of the information obtained, 93% (n=141 reported obtaining relevant information, 76% (n=115 current information, and 72% (n=109 accurate information. Nearly 70% were distributing information or resources to other people, and 68% were sharing or discussing information provided with colleagues. Nobody claimed that they had found little or nothing of value.Advice to patients, clients or carers was the most frequently cited impact category (n=104, 68%, followed by advice to colleagues (n=84, 55.3%.The main strengths of the service were the perceived reliability of the service, the current awareness and alerting service run from one site, and literature searching support for commissioning and public health enquiries. Respondents reported saving time, and the main cognitive impact was the perceived relevance of the information obtained. Service weaknesses identified related to accessibility issues such as parking, opening hours, and staff coverage, and outreach was identified as the main service development opportunity.Conclusion – The adaptation of an existing questionnaire provided a clear assessment of the effectiveness of a primary health care information service to a broad spectrum of users. Respondents identified what they valued about the service and how it could be improved.

  11. Adaptation of Impact Questions from an Existing Toolkit Provided Clear Assessment of Valued Service Elements and Desirable Service Improvements in a Primary Health Care Library and Information Service. A Review of: Urquhart, C., Thomas, R., Ovens, J., Lucking, W., & Villa, J. (2010). Planning changes to health library services on the basis of impact assessment. Health Information and Libraries Journal, 27(4), 277-285. doi: 10.1111/j.1471-1842.2010.00900.x

    OpenAIRE

    Kate Kelly

    2011-01-01

    Objective – To provide an action plan for the Knowledge, Resource and Information Service (KRIS) based on an impact assessment of current services, satisfaction with current services, and views on desirable improvements to service and service delivery.Design – Questionnaire for KRIS service users and interviews with KRIS staff.Setting – Two locations served by KRIS in the north and south of Bristol City in the UK – one a health promotion service and one a National Health Service (NHS) teachin...

  12. Rock Art Glossary: A Multilingual Dictionary, Expanded Second Edition (First Edition 2001. Edited by Robert G. Bednarik, Ahmed Achrati, Tang Huisheng, Alfred Muzzolini, George Dimitriadis, Dario Seglie, Fernando Coimbra, Yakov A. Sher and Mario Consens. Australian Rock Art Research Association, Inc., Melbourne, 2010; 274 Pages, in English, Arabic, Chinese, French, German, Greek, Italian, Portuguese, Russian and Spanish, with Translation Tables. Price $A 38.00, ISBN 978-0-646-53471-8

    Directory of Open Access Journals (Sweden)

    Shu-Kun Lin

    2013-02-01

    Full Text Available This is the first dictionary compiled specifically for rock art research. It follows the publication of an English rock art glossary in the journal Rock Art Research in November 2000. To be adopted by the International Federation of Rock Art Organisations (IFRAO, it has been translated by some of the world’s foremost scholars in the field into Arabic, Chinese, French, German, Greek, Italian, Portuguese, Spanish and Russian. In a discipline that has hitherto been without an agreed terminology, even communication within a single language has been difficult. The proliferation of idiosyncratic terminologies of often academically isolated researchers, many of which have been used by only one scholar, has not only retarded progress and the transference of knowledge, it has led to countless misunderstandings and even personal feuds. The purpose of this dictionary is to create a single terminological standard as well as a cross-lingual uniformity of usage. It focuses particularly on scientific aspects, technical applications and epistemological rigour. It does not set out to create a terminological straitjacket for the discipline, but a common standard of reference, particularly in areas that have in the past been susceptible to greatly differing interpretations. This dictionary comprises sections in ten languages, each listing the same terms alphabetically. It also contains a table interlinking all of these languages, listing all terms explained. This translation table is organised alphabetically according to the English terms. The volume is indispensable for scientific translators, rock art scholars, archaeologists and others concerned with aspects of pre-Historic rock art, and is also intended for the guidance of students and authors working in this field.

  13. Paul Scherrer Institute Scientific Report 1999. Volume I: Particles and Matter

    Energy Technology Data Exchange (ETDEWEB)

    Gobrecht, J.; Gaeggeler, H.; Herlach, D.; Junker, K.; Kettle, P.-R.; Kubik, P.; Zehnder, A. [eds.

    2000-07-01

    lthough originally planned for fundamental research in nuclear physics, the particle beams of pions, muons, protons and neutrons are now used in a large variety of disciplines in both natural science and medicine. The beams at PSI have the world's highest intensities and therefore allow certain experiments to be performed, which would not be possible elsewhere. The highlight of research this year was the first-ever determination of the chemical properties of the superheavy element {sup 107} Bohrium. This was undertaken, by an international team led by H. Gaeggeler of PSI's Laboratory for Radiochemistry. Bohrium was produced by bombarding a Berkelium target with Neon ions from the Injector I cyclotron and six atoms were detected after having passed through an online gas chromatography device. At the Laboratory for Particle Physics the focus has shifted from nuclear physics to elementary particle physics with about a fifty-fifty split between investigations of rare processes or particle decays using the high intensity muon, pion and recently also polarized neutron beams of PSI, and research at the highest energy frontier at CERN (Geneva) and DESY (Hamburg). Important space instrumentation has been contributed by the Laboratory for Astrophysics to the European Space Agency and NASA satellite programmes. The Laboratory for Micro and Nanotechnology continued to focus on research into molecular nanotechnology and SiGeC nanostructures, the latter with the aim of producing silicon based optoelectronics. Progress in 1999 in these topical areas is described in this report. A list of scientific publications in 1999 is also provided.

  14. EST Table: FY741742 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available FY741742 E_FL_famL_16A21_F_0 11/11/04 95 %/274 aa ref|NP_001037126.1| ribosomal pro...tein L3 [Bombyx mori] gb|AAV34812.1| ribosomal protein L3 [Bombyx mori] 11/11/04 72 %/274 aa FBpp0176673|Dpe...PA Protein|2R:39456604:39459567:1|gene:AGAP003556 11/11/04 78 %/274 aa gnl|Amel|GB15261-PA 11/11/04 78 %/274

  15. Protein (Viridiplantae): 746637 [PGDBj - Ortholog DB

    Lifescience Database Archive (English)

    Full Text Available 218 ... 38832:274 ... 38833:414 ... 564608:414 predicted protein Micromonas pusilla CCMP1545 MAQLPSYEVDDGEDSMPGAPGEGPMTDSMQGPPVEVPTSDSM...PGAPGEVPTMDSMHGPPVEVPTMDSMHGAPVEVPMMDSMPGAPVEVPTMDSMQGPPVEVPTMDSMQGAPGEGPMTDSMHGAPGEGPTMDSMNSGNPTKCVVPDWCSTYPPEMQKSKPECQCPDDSHP

  16. 10 CFR 150.31 - Requirements for Agreement State regulation of byproduct material.

    Science.gov (United States)

    2010-01-01

    ... REGULATORY AUTHORITY IN AGREEMENT STATES AND IN OFFSHORE WATERS UNDER SECTION 274 Enforcement § 150.31... long term impacts, including decommissioning, decontamination, and reclamation impacts associated...

  17. Drug: D05273 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D05273 Drug Ormetoprim (USAN/INN) C14H18N4O2 274.143 274.3183 D05273.gif Antibacterial... Component of Rofenaid (TN) veterinary medicine Trimethoprim [DR:D00145] derivative Antiinfectives [BR:br08307] Antibacterial

  18. EST Table: FS914277 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available FS914277 E_FL_fufe_31M22_F_0 10/09/28 37 %/274 aa ref|XP_969699.1| PREDICTED: similar to fuzzy.../274 aa gi|91081315|ref|XP_969699.1| PREDICTED: similar to fuzzy CG13396-PA [Tribolium castaneum] CK514734 fufe ...

  19. 2011 Montana Youth Risk Behavior Survey: Alternative Schools

    Science.gov (United States)

    Montana Office of Public Instruction, 2011

    2011-01-01

    This report presents the 2011 Montana Youth Risk Behavior alternative school student frequency distributions. These frequency distributions are based upon surveys with 274 alternative school students in Montana during February of 2011. Frequency distributions may not total 274 due to nonresponse and percents may not total 100 percent due to…

  20. UNC Pembroke Laser Scanning Confocal Microscopy Facility

    Science.gov (United States)

    2016-04-29

    ataxia type 28 (SCA28) model. J Clin Invest 125:263-274. Melo CV, Okumoto S, Gomes JR, Baptista MS, Bahr BA, Frommer WB, and Duarte CB (2013...ataxia in the spinocerebellar ataxia type 28 (SCA28) model. J Clin Invest 125:263-274. Melo CV, Okumoto S, Gomes JR, Baptista MS, Bahr BA, Frommer WB

  1. 26 CFR 301.7701(b)-3 - Days of presence in the United States that are excluded for purposes of section 7701(b).

    Science.gov (United States)

    2010-04-01

    ... compete in a charitable sports event described in section 274(l)(1)(B). For purposes of computing the days... sports event described in section 274(l)(1)(B) shall be excluded. Thus, days on which the individual is... on that date as a result of the injuries suffered in the accident. B recovered from the injuries...

  2. The Development of Therapeutic and Diagnostic Countermeasures to WMD by the Advanced Medical Countermeasures Consortium

    Science.gov (United States)

    2008-09-01

    Papirmeister, B., Brinkley, F.B., Johnson, J.B., 1985. Sulfurmus- tard lowers nicotinamide adenine dinucleotide concentrations in human skin grafted to nude...07pm Compositor Name: BMani 247 B. Skin ...274 1. Role of Skin Mast Cells in Vesicant Toxicity...................................................... 274 C. Eyes

  3. Cholinesterase Structure: Identification of Residues and Domains Affecting Organophosphate Inhibition and Catalysis

    Science.gov (United States)

    1998-04-01

    269-274, 1997. ISSN 0006-2952/97/$17.00 + 0.00 "© 1997 Elsevier Science Inc . All rights reserved. PII S0006-2952(97)00180-9 ELSEVIER Mutant...potential candidates for pre- or post-exposure treatment for OP toxicity. BIOCHEM PHARMACOL 54;2:269-274, 1997. © 1997 Elsevier Science Inc . KEY WORDS

  4. 28 CFR 68.57 - Judicial review of the final agency order of an Administrative Law Judge in cases arising under...

    Science.gov (United States)

    2010-07-01

    ... of an Administrative Law Judge in cases arising under section 274B. 68.57 Section 68.57 Judicial... BEFORE ADMINISTRATIVE LAW JUDGES IN CASES INVOLVING ALLEGATIONS OF UNLAWFUL EMPLOYMENT OF ALIENS, UNFAIR... of an Administrative Law Judge in cases arising under section 274B. Any person aggrieved by a final...

  5. The Serratia gene cluster encoding biosynthesis of the red antibiotic, prodigiosin, shows species- and strain-dependent genome context variation

    DEFF Research Database (Denmark)

    Harris, Abigail K P; Williamson, Neil R; Slater, Holly

    2004-01-01

    The prodigiosin biosynthesis gene cluster (pig cluster) from two strains of Serratia (S. marcescens ATCC 274 and Serratia sp. ATCC 39006) has been cloned, sequenced and expressed in heterologous hosts. Sequence analysis of the respective pig clusters revealed 14 ORFs in S. marcescens ATCC 274 and...

  6. Buffering Capacity of Pigmented and Nonpigmented Strains of Serratia marcescens

    Science.gov (United States)

    Rius, Núria; Solé, Montserrat; Francia, Alicia; Lorén, José G.

    1994-01-01

    The pigmented strain Serratia marcescens ATCC 274 had a higher buffering capacity and a higher membrane H+ conductance than S. marcescens GP, a spontaneous nonpigmented mutant of ATCC 274. The data suggest that mutations which apparently affect only the synthesis of a secondary metabolite can modify buffering capacity and passive H+ conductance. PMID:16349300

  7. Protein (Viridiplantae): 255551869 [PGDBj - Ortholog DB

    Lifescience Database Archive (English)

    Full Text Available 24:274 3398:274 71240:556 91827:556 71275:1304 91835:679 3646:4388 3977:2966 235629:2966 235880:2966 3987:2966 3988:2966 Protein peng...uin, putative Ricinus communis MAAKKQEKKRKQNSDAKNVTDSLPSKKPKLNEKFKKPFDPSKKLNDKSKLGQ

  8. Drug: D06260 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D06260 Drug Tybamate (USP/INN); Solacen (TN) C13H26N2O4 274.1893 274.3565 D06260.gi...f Tranquilizer [minor] CAS: 4268-36-4 PubChem: 47207918 LigandBox: D06260 NIKKAJI: J8.698C ATOM 19 1 C1a C 8

  9. 78 FR 52219 - State of Georgia Relinquishment of Sealed Source and Device Evaluation and Approval Authority

    Science.gov (United States)

    2013-08-22

    ...-415- 7135; email: Stephen.Poy@nrc.gov . SUPPLEMENTARY INFORMATION: Section 274b. of the Atomic Energy... and activities. On December 15, 1969, Georgia entered into a Section 274b. Agreement with the Atomic... special nuclear material in quantities not sufficient to form a critical mass. Currently, the State...

  10. Experiment list: SRX573052 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available wild-type Hela Cells || antibody=anti-INTS11 rabbit polyclonal (Bethyl, A301-274A...) || source=IP with Ab anti-INTS11 rabbit polyclonal (Bethyl, A301-274A) || sample type=ChIP-seq http://dbar

  11. Experiment list: SRX573051 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ld-type Hela Cells || antibody=anti-INTS11 rabbit polyclonal (Bethyl, A301-274A) ...|| source=IP with Ab anti-INTS11 rabbit polyclonal (Bethyl, A301-274A) || sample type=ChIP-seq http://dbarch

  12. Experiment list: SRX573053 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ild-type Hela Cells || antibody=anti-INTS11 rabbit polyclonal (Bethyl, A301-274A)... || source=IP with Ab anti-INTS11 rabbit polyclonal (Bethyl, A301-274A) || sample type=ChIP-seq http://dbarc

  13. Experiment list: SRX573054 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available wild-type Hela Cells || antibody=anti-INTS11 rabbit polyclonal (Bethyl, A301-274A...) || source=IP with Ab anti-INTS11 rabbit polyclonal (Bethyl, A301-274A) || sample type=ChIP-seq http://dbar

  14. Cultural Resources of the Ohio River Valley in Indiana,

    Science.gov (United States)

    1977-07-01

    1963) "Early Crab Orchard" Sugar Hill cordmarked pottery (Maxwell 1951:273-274) Crab Orchard series pottery without nodes (MIaxwell 1951:274- 278...Fuller. Madison. Brunett , F. n.d. Plant remains from the Angel Mounds site, Indiana. Masters Thesis (unpublished), University of Michigan, Ann Arbor

  15. A 2011 Risk/Benefit Analysis of the Anthrax Vaccine Immunization Program

    Science.gov (United States)

    2011-06-10

    5.pdf (accessed 17 October 2010). 11 rich concentration of organic matter, and changes in the soil microenvironment secondary to increased...Sciences in 2002, and multiple post marketing safety studies.279 274Ibid. 275Ibid. 276Ibid., 5

  16. AcEST: DK945607 [AcEST

    Lifescience Database Archive (English)

    Full Text Available =Vitis... 33 5.6 tr|Q24748|Q24748_DROVI Mobile elemnt gypsy, complete OS=Drosophi...t: 274 QYAPYYNMPAQTPHAPYMSSHTGHASFNVAVAAAQSSHMQFHGLYHS 320 >tr|Q24748|Q24748_DROVI Mobile elemnt gypsy, comp

  17. Why Are Drugs So Hard to Quit?

    Medline Plus

    Full Text Available ... in the Brain, Animation. - Duration: 4:16. Alila Medical Media 306,274 views 4:16 Top 10 Most ... Investigating Drug Abuse: Brain Imaging - Duration: 1:51. National Institute on Drug Abuse ( ...

  18. 78 FR 76293 - Combined Notice of Filings

    Science.gov (United States)

    2013-12-17

    ...: RP14-274-000. Applicants: NGO Transmission, Inc. Description: NGO Transmission, Inc. submits tariff filing per 154.204: NGO Transmission, Inc.--Negotiated Rate Filing to be effective 1/1/2014. Filed...

  19. 78 FR 79567 - Supplemental Nutrition Assistance Program: Trafficking Controls and Fraud Investigations

    Science.gov (United States)

    2013-12-31

    ... 271 and 274 RIN 0584-AE26 Supplemental Nutrition Assistance Program: Trafficking Controls and Fraud... Assistance Program: Trafficking Controls and Fraud Investigations was published on August 21, 2013. The ICR...

  20. 76 FR 62819 - Notice of Intent To Amend the Resource Management Plan for the San Luis Resource Area, Colorado...

    Science.gov (United States)

    2011-10-11

    ... Lucero, Interdisciplinary Team Lead, (719) 274-6327; see address above; e-mail jlucero@blm.gov . Persons... interdisciplinary approach to develop the RMP amendment in order to consider the resource issues and...

  1. 75 FR 27544 - National Institute on Disability and Rehabilitation Research (NIDRR)-Disability and...

    Science.gov (United States)

    2010-05-17

    ...- Based Practice. Psychiatric Rehabilitation Journal, 27(4), 345-359. Canadian Institutes of Health... National Institute on Disability and Rehabilitation Research (NIDRR)--Disability and Rehabilitation Research Projects and Centers Program--Disability Rehabilitation Research Project (DRRP)--Center...

  2. Snowy plover survey: Great Salt Lake, UT: Summary report 2007

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — The snowy plover survey was conducted in the Great Salt Lake ecosystem from 7 May - 7 June 2007. A total of 274 clusters were surveyed and 659 birds counted. The...

  3. 76 FR 58138 - Defense Federal Acquisition Regulation Supplement (DFARS); Alternative Line Item Structure (DFARS...

    Science.gov (United States)

    2011-09-20

    ... regulatory approaches that maximize net benefits (including potential economic, environmental, public health...). (C) Use the clause at 252.211-7003, Item Identification and Valuation, as prescribed in 211.274-4....

  4. 76 FR 21847 - Defense Federal Acquisition Regulation Supplement (DFARS), Alternative Line-Item Structure (DFARS...

    Science.gov (United States)

    2011-04-19

    ... economic, environmental, public health and safety effects, distributive impacts, and equity). Executive... Identification and Valuation, as prescribed in 211.274-4. (D) Use the clause at 252.211-7006, Radio...

  5. 75 FR 41123 - Fisheries of the Exclusive Economic Zone Off Alaska; Bering Sea Subarea

    Science.gov (United States)

    2010-07-15

    ... (27.4 m) lengths. By working with the nonpelagic trawl fishing industry, the AFSC determined that... trawling for the purpose of studying the effects of nonpelagic trawling on bottom habitat. The SMIHCA...

  6. Incidence of PTLD in pediatric renal transplant recipients receiving basiliximab, calcineurin inhibitor, sirolimus and steroids

    NARCIS (Netherlands)

    McDonald, R. A.; Smith, J. M.; Ho, M.; Lindblad, R.; Ikle, D.; Grimm, P.; Wyatt, R.; Arar, M.; Liereman, D.; Bridges, N.; Harmon, W.

    2008-01-01

    Pediatric renal transplant recipients were enrolled in a multicenter, randomized, double-blind trial of steroid withdrawal. Subjects received basiliximab, calcineurin inhibitor, sirolimus and steroids. Of 274 subjects enrolled, 19 (6.9%) subjects developed posttransplant lymphoproliferative disorder

  7. Microbiology of chronic suppurative otitis media at Queen Elizabeth ...

    African Journals Online (AJOL)

    Malawi Medical Journal; 27(4): 120-124 December 2015. Maximizing ... Knowledge of the true frequency of polymicrobial infection, particularly ... contamination with normal skin flora like Staphylococcus ..... Streptococcus pyogenes. 3. 1.9%.

  8. 76 FR 20036 - Clifton D. Burt, M.D.; Revocation of Registration

    Science.gov (United States)

    2011-04-11

    ... prevent addiction and recreational abuse. As a corollary, also bars doctors from peddling to patients who crave the drugs for those prohibited uses.'' Gonzales v. Oregon, 546 U.S. 243, 274 (2006) (citing United...

  9. 75 FR 49992 - Peter W.S. Grigg, M.D.; Revocation of Registration

    Science.gov (United States)

    2010-08-16

    ... prevent addiction and recreational abuse. As a corollary, also bars doctors from peddling to patients who crave the drugs for those prohibited uses.'' Gonzales v. Oregon, 546 U.S. 243, 274 (2006) (citing United...

  10. The comparative effect of an addition of a surface term to the Woods-Saxon potential on the thermodynamics of a nucleon

    CERN Document Server

    Lütfüoğlu, B C

    2016-01-01

    In this study, we reveal the difference between Woods-Saxon (WS) and Generalized Symmetric Woods-Saxon (GSWS) potentials in order to describe the physical properties of a nucleon, by means of solving Schr\\"odinger equation for the two potentials. The additional term squeezes the WS potential well, which leads an upward shift in the spectrum, resulting in a more realistic picture. The resulting GSWS potential does not merely accommodate extra quasi bound states, but also has modified bound state spectrum. As an application, we apply the formalism to a real problem, an $\\alpha$ particle confined in Bohrium-$270$ nucleus. The thermodynamic functions Helmholtz energy, entropy, internal energy, specific heat of the system are calculated and compared in both wells. The internal energy and the specific heat capacity increase, as a result of upward shift in the spectrum. The shift of the Helmholtz free energy is a direct consequence of the shift of the spectrum. The entropy decreases because of a decrement in the num...

  11. Analyzing Evolving Social Network 2 (EVOLVE2)

    Science.gov (United States)

    2015-04-01

    COVERED (From - To) JUN 2012 – OCT 2014 4. TITLE AND SUBTITLE ANALYZING EVOLVING SOCIAL NETWORKS 2 (EVOLVE2) 5a. CONTRACT NUMBER FA8750-12-2-0186... jazz 198 2742 274 0.14 connect 1095 7825 783 0.014 hep-th 8710 14254 1425 0.0003 netscience 1461 2742 274 0.0013 imdb 6260 98235 9824 0.005 technological

  12. EST Table: FS912812 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available FS912812 E_FL_fufe_27F15_F_0 10/09/28 50 %/274 aa ref|XP_970789.1| PREDICTED: similar to Integrat... aa gnl|Amel|GB19912-PA 10/09/10 50 %/274 aa gi|91082039|ref|XP_970789.1| PREDICTED: similar to Integrator complex subunit 4 (Int4) [Tribolium castaneum] FS906031 fufe ...

  13. Antipeptide antibodies that can distinguish specific subunit polypeptides of glutamine synthetase from bean (Phaseolus vulgaris L.)

    Science.gov (United States)

    Cai, X.; Henry, R. L.; Takemoto, L. J.; Guikema, J. A.; Wong, P. P.; Spooner, B. S. (Principal Investigator)

    1992-01-01

    The amino acid sequences of the beta and gamma subunit polypeptides of glutamine synthetase from bean (Phaseolus vulgaris L.) root nodules are very similar. However, there are small regions within the sequences that are significantly different between the two polypeptides. The sequences between amino acids 2 and 9 and between 264 and 274 are examples. Three peptides (gamma 2-9, gamma 264-274, and beta 264-274) corresponding to these sequences were synthesized. Antibodies against these peptides were raised in rabbits and purified with corresponding peptide-Sepharose affinity chromatography. Western blot analysis of polyacrylamide gel electrophoresis of bean nodule proteins demonstrated that the anti-beta 264-274 antibodies reacted specifically with the beta polypeptide and the anti-gamma 264-274 and anti-gamma 2-9 antibodies reacted specifically with the gamma polypeptide of the native and denatured glutamine synthetase. These results showed the feasibility of using synthetic peptides in developing antibodies that are capable of distinguishing proteins with similar primary structures.

  14. Antipeptide antibodies that can distinguish specific subunit polypeptides of glutamine synthetase from bean (Phaseolus vulgaris L.)

    Science.gov (United States)

    Cai, X.; Henry, R. L.; Takemoto, L. J.; Guikema, J. A.; Wong, P. P.; Spooner, B. S. (Principal Investigator)

    1992-01-01

    The amino acid sequences of the beta and gamma subunit polypeptides of glutamine synthetase from bean (Phaseolus vulgaris L.) root nodules are very similar. However, there are small regions within the sequences that are significantly different between the two polypeptides. The sequences between amino acids 2 and 9 and between 264 and 274 are examples. Three peptides (gamma 2-9, gamma 264-274, and beta 264-274) corresponding to these sequences were synthesized. Antibodies against these peptides were raised in rabbits and purified with corresponding peptide-Sepharose affinity chromatography. Western blot analysis of polyacrylamide gel electrophoresis of bean nodule proteins demonstrated that the anti-beta 264-274 antibodies reacted specifically with the beta polypeptide and the anti-gamma 264-274 and anti-gamma 2-9 antibodies reacted specifically with the gamma polypeptide of the native and denatured glutamine synthetase. These results showed the feasibility of using synthetic peptides in developing antibodies that are capable of distinguishing proteins with similar primary structures.

  15. Properties of Group Five and Group Seven transactinium elements

    Energy Technology Data Exchange (ETDEWEB)

    Wilk, Philip A. [Univ. of California, Berkeley, CA (United States)

    2001-05-01

    The detection and positive identification of the short-lived, low cross section isotopes used in the chemical studies of the heaviest elements are usually accomplished by measuring their alpha-decay, thus the nuclear properties of the heaviest elements must be examined simultaneously with their chemical properties. The isotopes 224 Pa and 266,267 Bh have been studied extensively as an integral part of the investigation of the heaviest members of the groups five and seven of the periodic table. The half-life of 224 Pa was determined to be 855 ±19 ms by measuring its alpha-decay using our rotating wheel, solid state detector system at the Lawrence Berkeley National Laboratory 88-Inch Cyclotron. Protactinium was produced by bombardment of a bismuth target. New neutron rich isotopes, 267 Bh and 266 Bh, were produced in bombardments of a 249 Bk target and their decay was observed using the rotating wheel system. The 266 Bh that was produced decays with a half-life of approximately 1 s by emission of alpha particles with an average energy of 9.25 plus/minus 0.03 MeV. 267 Bh was observed to decay with a 17 s half-life by emission of alpha-particles with an average energy of 8.83 plus/minus 0.03 MeV. The chemical behavior of hafnium, Ha (element 105) was investigated using the fast on-line continuous liquid extraction and detection system SISAK-LISSY. Hafnium was not observed in this experiment following transport and extraction. Protactinium was used as on-line test of the apparatus to determine the experimental efficiency of the entire system. Unfortunately, the amount of protactinium observed after the extraction, compared to the amount produced, was extremely small, only 2.5%. The extraction of the protactinium isotope indicated the efficiency of the apparatus was too low to observe the extraction of hafnium. The chemical behavior of oxychloride compounds of bohrium was

  16. Properties of Group Five and Group Seven transactinium elements

    Energy Technology Data Exchange (ETDEWEB)

    Wilk, Philip A.

    2001-05-01

    The detection and positive identification of the short-lived, low cross section isotopes used in the chemical studies of the heaviest elements are usually accomplished by measuring their alpha-decay, thus the nuclear properties of the heaviest elements must be examined simultaneously with their chemical properties. The isotopes 224 Pa and 266,267 Bh have been studied extensively as an integral part of the investigation of the heaviest members of the groups five and seven of the periodic table. The half-life of 224 Pa was determined to be 855 plus/minus19 ms by measuring its alpha-decay using our rotating wheel, solid state detector system at the Lawrence Berkeley National Laboratory 88-Inch Cyclotron. Protactinium was produced by bombardment of a bismuth target. New neutron rich isotopes, 267 Bh and 266 Bh, were produced in bombardments of a 249 Bk target and their decay was observed using the rotating wheel system. The 266 Bh that was produced decays with a half-life of approximately 1 s by emission of alpha particles with an average energy of 9.25 plus/minus 0.03 MeV. 267 Bh was observed to decay with a 17 s half-life by emission of alpha-particles with an average energy of 8.83 plus/minus 0.03 MeV. The chemical behavior of hafnium, Ha (element 105) was investigated using the fast on-line continuous liquid extraction and detection system SISAK-LISSY. Hafnium was not observed in this experiment following transport and extraction. Protactinium was used as on-line test of the apparatus to determine the experimental efficiency of the entire system. Unfortunately, the amount of protactinium observed after the extraction, compared to the amount produced, was extremely small, only 2.5%. The extraction of the protactinium isotope indicated the efficiency of the apparatus was too low to observe the extraction of hafnium. The chemical behavior of oxychloride compounds of bohrium was investigated by isothermal gas adsorption chromatography in a quartz column at 180, 150

  17. An experimental paradigm opening the world of superheavy elements

    Science.gov (United States)

    Armbruster, P.; Münzenberg, Gottfried

    2012-07-01

    The history of the discovery of the six elements Z = 107 ∓ 112, bohrium, hassium, meitnerium, darmstadtium, roentgenium, and copernicium goes back to the early 1960s. An experimental method to separate and identify rare nuclear reaction products, the recoil separation, was developed and optimised for beams of fission products at European research reactors. Chemical elements beyond the then first transactinides ( Z = 104), which owe their stability to the internal structure of atomic nuclei, were predicted theoretically. A big brother of the shell-stabilised nucleus 208Pb, a spherical magic nucleus at Z = 114∓126 and N = 184, might reach lifetimes long enough to be detected. In the seventies, hunting superheavy elements (SHE) was on the agenda of nuclear chemistry. Could the Periodic Table of Elements be extended to Z = 120, and is the order of electrons in the atom still following the laws established for lighter elements? In Germany, the heavy ion accelerator (UNILAC) was built by Christoph Schmelzer and his team at GSI, Darmstadt. SHE and UNILAC met the recoil separators in 1968, and SHIP (Separator for Heavy Ion reaction Products) was ready together with the first UNILAC-beams in 1976. Recoil separation is orders of magnitude more sensitive, selective, and faster than earlier methods used to synthesise elements up to seaborgium, Z = 106. The experimental paradigm we introduced opened the world of SHEs. At SHIP we discovered and investigated the elements Z = 107∓112 in the years 1980-2000. Our laboratory was the world champion during this time. Today our experimental method is used worldwide in the search for SHEs, but the leadership went to the Russian laboratory JINR in Dubna, which extended the Periodic Table by 6 more elements to Z = 118, the candidate for the next rare gas.

  18. Use of osteoplastic material to guide bone tissue regeneration deffect.

    Science.gov (United States)

    Machavariani, A; Mazmishvili, K; Grdzelidze, T; Menabde, G; Amiranashvili, I

    2011-12-01

    The goal of research was study of restoration processes in jaw-teeth bone defects by application of osteoplastic materials in the experiment. The experiment was performed over 32 white (6-12 month old) rats; the animals were divided into 2 groups; 16 animals were enrolled in the first group; the section was performed in the edge of lower jaw; the lower jaw body was revealed. Under the effect of the dental drilling machine and the # 1 cooling mean by the fissure bohrium (distilled water) the defect of the dimension of 2x2 mm was created; the defect was washed by 0/9% saline to remove the bone sawdust; the wound was sutured tightly, in layers. The second group of the experiment was staffed with 16 animals (main group); the similar bone defect of the size 2 x 2mm was created on the rat's jaw's body. After washing of modeled defect we inserted osteopathic materials PORESORB-TCP crystals with the size of 0,6-1.0 mm the wound was sutured tightly, in layers. After the 3-rd, 15-th, 30-th and 90-th days from the date of operation there was performed X-ray and morphological examination over the animals in the control as well as the main group. The analysis of the examination performed over the experimental materials showed that in the control group in samples taken at 90th day the defects were not completely restored. In the test group in samples taken at 90th day reparative regeneration is confirmed. This is stimulated by the factor that within the main group's animals the defect regeneration process is supported with the osteoplastic material PORESORB-TCP.

  19. Synthesis of the heaviest nuclei in cold fusion reactions

    Science.gov (United States)

    Münzenberg, G.; Morita, K.

    2015-12-01

    Cold fusion of heavy ions paved the way to superheavy elements. It was proposed by Yu.Ts. Oganessian more than forty years ago in 1974 [1,2]. First experiments were carried out at JINR Dubna, starting with the reaction 40Ar + 208Pb → 248Fm* where several hundreds to thousand atoms were produced on one day. The large production rate indicating an enhancement of the fusion cross section, especially for the evaporation of two or three neutrons, proved the concept of cold-fusion with the use of the doubly magic nucleus 208Pb as a target. The Dubna experiments were extended to the transactinide region beyond rutherfordium. The breakthrough came with the separation in-flight. Two different approaches were used: kinematic separation with the velocity filter SHIP [3] at GSI Darmstadt, and with the gasfilled separator GARIS [4,5] at RIKEN. With SHIP the concept of cold fusion of massive nuclear systems was convincingly confirmed by the observation of the one-neutron evaporation channel in the production of 247Rf in an irradiation of 208Pb with 50Ti [6] in 1981 which opened the way to the transactinide region. At SHIP the elements bohrium (107) to copernicium (112) were discovered [7]. A new closed shell region around hassium was found. The RIKEN experiments started in 2002. They confirmed the GSI results and in addition improved the data on structure and production of elements hassium to copernicium significantly. The heaviest element ever created in a cold fusion reaction, Z = 113, was observed at GARIS [8,9].

  20. Modeling Vessel-Generated Currents and Bed Shear Stresses

    Science.gov (United States)

    2008-06-01

    Vessel 1, the fraction of the draft applied over PBOW is 0.95. CSTR 1 0.95 For Vessel 1, the fraction of the draft applied over PSTR is 0.95...vessel draft is 0.95. CSTR 2 0.95 For Vessel 2, the ratio of the stern length to the vessel length is 0.95. PROP 2 1 2.74 6 52 5 The propellers...PBOW 1 0.1 PSTR 1 0.1 CBOW 1 0.95 CSTR 1 0.95 PROP 1 2 2.74 6 52.5 SDEF 1 1 0 -3080.0 -1.5 2.9 FDEF 2 1 -6955.0 -1.5 2.9 DRFT 2 2.74 BLEN 2

  1. The Role of Intuition in the Decision-Making Processes of United States Air Force Field Grade Officers

    Science.gov (United States)

    1989-12-01

    INTJ J I ISTP ISFP INFP INTP P E ESTP ESFP ENFP ENTP P E ESTJ ESFJ ENFJ ENTJ J T P F T Value of the MBTI. The MBTI has been used extensively since its...6.85 6.44 INFJ 2.74 3.41 INFP 6.85 6.06 ENFP 10.96 8.71 ENFJ 1.37 2.65 INTJ 6.85 3.03 INTP 0 1.52 ENTP 5.48 5.30 ENTJ 2.74 4.92 69 Intuition and the

  2. Pressure dependence of BaNi2As2

    Energy Technology Data Exchange (ETDEWEB)

    Ronning, Filip [Los Alamos National Laboratory; Park, Tuscon [Los Alamos National Laboratory; Bauer, Eric D [Los Alamos National Laboratory; Thompson, Joe D [Los Alamos National Laboratory

    2009-01-01

    We report results from resistivity measurements of BaNi{sub 2}As{sub 2} up to 27.4 kbar of pressure. We find the structural transition at 130 K is broadened slightly with increasing pressure. There is also minimal influence on the superconducting transition, where the resistive onset increases from 2 to 3 K, but the temperature at which zero resistance is obtained is unchanged up to 27.4 kbar. This behavior is in contrast to that observed in the Fe-based systems as well as in LaNiPO and LaNiAsO.

  3. La statistique industrielle de 1861 à 1896

    OpenAIRE

    2011-01-01

       Titre Niveau Documentation Fichier 1 Fichier 2 Statistique industrielle, 1861-1865 Département DS274.pdf DS274.xls Statistique industrielle, 1861-1865 Département DS275.pdf DS275.xls Statistique industrielle, 1861-1865 Chef-Lieu DS276.pdf DS276.xls Statistique industrielle, 1873 Département DS277.pdf DS277.xls Statistique industrielle, 1873 Département DS278.pdf DS278.xls Statistique industrielle, 1896 Département DS301.pdf DS301_1.xls DS301_2.xls Statistique industrielle, 1896 Département...

  4. CTC Sentinel. Volume 7, Issue 10, October 2014

    Science.gov (United States)

    2014-10-01

    objective was to 7 United States of America v Liberty Reserve S.A, No. USA -33s-274 (Ed. 9-25-58), United States District Court, Southern District of...Ross William Ulbricht, USA - 33s-274 (Ed. 9-25-58), United States District Court, Southern District of New York, February 4, 2014. 12 Tor is free...20 These discussions were posted to the Shumukh al- Islam Network on April 29, 2013. oCToBeR 2014 . VoL 7. IssUE 10 “Cryptography is a never- ending

  5. Protecting America Through Better Civic Education

    Science.gov (United States)

    2013-09-01

    representing the process of how an individual radicalizes and finally commits an act of violence presents several possible factors that may suggest the...27 Audiologist 3.99 Elementary—Pre- Kindergarten 2.74 Physical Therapist 3.91 Art/Visual Education 2.74 Languages—Spanish 3.88 Elementary...with Some Surplus (2.60–1.81) Technology Education 3.58 Health Education 2.57 Languages—Japanese 3.53 Elementary— Kindergarten 2.52

  6. Data of evolutionary structure change: 1B38A-1WBSA [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 1B38A-1WBSA 1B38 1WBS A A -----------------MENFQKVEKIGEGTYGVVYKAR... ALA CA 254 ILE CA 274 1WBS A 1WBSA VKKLSRPFQSIIHA PRO CA 313 ASN CA 408 ILE CA 432 1WBS... A 1WBSA RELRLLKHMKHENV

  7. Stable Hydrogen and Oxygen Isotope Ratios for Selected Sites of the U.S. Geological Survey’s NASQAN and Benchmark Surface-Water Networks

    Science.gov (United States)

    2000-01-01

    274 Ohio 03159510 Hocking River Below Athens .................................................................................275...369 12039300 North Fork Quinault River Near Amanda Park...Kanawha River At Palestine WV 54 N 39.05972 81.3903 1515 05030203 585.51 03159510 Hocking River Below Athens OH 39 N 39.32749 82.0050 957 05030204

  8. Variation in working effort in Danish Little Owls Athene noctua

    DEFF Research Database (Denmark)

    Holsegård-Rasmussen, Miriam H.; Sunde, Peter; Thorup, K.

    2009-01-01

    with extinction. The study is based on 143 one-hour surveys of breeding and 274 surveys of non-breeding Little Owls (27 territorial individuals on 14 territories). Working effort is calculated as the total linear distance between all observed consecutive telemetry fixes during one-hour surveys (Minimum Flight...

  9. Experimental/Computational Studies of Combined Cycle Propulsion: Physics and Transient Phenomena in Inlets and Scramjet Combustors

    Science.gov (United States)

    2010-10-01

    Fellow (Stanford University) d) Graduate Students supported all or in part on this grant Justin Wagner - Graduate Student (UT Austin) Agustin Valdivia...Mechanics Meeting, San Diego, CA, February, Paper Number AAS-10-274, 2010. 12. MacMartin, D., "Dynamics and Control of Shock Motion in aNear-Isentropic

  10. Effect of Chronic Dietary Copper Exposure on Haematology and ...

    African Journals Online (AJOL)

    Michael Horsfall

    This was confirmed by a 4.4 and 7.1-fold increase in the liver copper of fish fed diet 2 and diet 3 ... naturally in lake with high fecundity and hatchability ... temperature 27.4 ± 0.420C and left unfed in the first 2 ... to prevent lipid oxidation.

  11. Curating seeds and other genetic resources for ethnobiology. In: Salick,J.Konchar, K. and Nesbitt, M., editors. Curatring Biocultural Collections: A handbook

    Science.gov (United States)

    The National Center for Genetic Resources Preservation (NCGRP) is one of the largest genebanks in the world, currently safeguarding over 875,000 plant collections and 652,295 animal collections, most with agriculture emphasis. This number represents 7,474 different plant species of 1,274 genera. T...

  12. 48 CFR 252.211-7003 - Item identification and valuation.

    Science.gov (United States)

    2010-10-01

    ... in this clause— Automatic identification device means a device, such as a reader or interrogator... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Item identification and... of Provisions And Clauses 252.211-7003 Item identification and valuation. As prescribed in 211.274-6...

  13. Gclust Server: 82030 [Gclust Server

    Lifescience Database Archive (English)

    Full Text Available 82030 Rpa2_RPD_3895 Cluster Sequences Related Sequences(299) 274 aldo/keto reductas...e 1 1.00e-35 0.0 0.0 0.0 6.67 0.0 0.0 Show 82030 Cluster ID 82030 Sequence ID Rpa2_RPD_3895 Link to cluster

  14. Gclust Server: 203027 [Gclust Server

    Lifescience Database Archive (English)

    Full Text Available 203027 OSA_Os11g0438500 Cluster Sequences - 274 no annotation 1 1.00e-99 14.29 0.0 0.0 0.0 0.0 0.0 Show 2030...27 Cluster ID 203027 Sequence ID OSA_Os11g0438500 Link to cluster sequences Cluster

  15. 75 FR 80426 - Defense Federal Acquisition Regulation Supplement; Reporting of Government-Furnished Property

    Science.gov (United States)

    2010-12-22

    ... serially managed, mission essential, sensitive, or controlled inventory. While the proposed rule adds... payments; (4) Intellectual property or software; and (5) Real property. 4. Revise section 211.274-6 to read..., as prescribed in 246.371. (L) Use the provision at 252.247-7026, Evaluation Preference for Use...

  16. 75 FR 64120 - Technical Amendments to Forms N-CSR and N-SAR in Connection With the Comprehensive Iran Sanctions...

    Science.gov (United States)

    2010-10-19

    ... COMMISSION 17 CFR Parts 249 and 274 Technical Amendments to Forms N-CSR and N-SAR in Connection With the... adopting technical amendments to Forms N-CSR and N-SAR under the Securities Exchange Act of 1934 and the... Securities and Exchange Commission (``Commission'') is adopting technical amendments to Form N-CSR \\1\\...

  17. Results of the Cord Blood Transplantation Study (COBLT) : clinical outcomes of unrelated donor umbilical cord blood transplantation in pediatric patients with hematologic malignancies

    NARCIS (Netherlands)

    Kurtzberg, Joanne; Prasad, Vinod K.; Carter, Shelly L.; Wagner, John E.; Baxter-Lowe, Lee Ann; Wall, Donna; Kapoor, Neena; Guinan, Eva C.; Feig, Stephen A.; Wagner, Elizabeth L.; Kernan, Nancy A.

    2008-01-01

    Outcomes of unrelated donor cord blood transplantation in 191 hematologic malignancy children (median age, 7.7 years; median weight, 25.9 kg) enrolled between 1999 and 2003 were studied (median follow-up, 27.4 months) in a prospective phase 2 multicenter trial. Human leukocyte antigen (HLA) matching

  18. Domain Modeling: NP_065184.2 [SAHG[Archive

    Lifescience Database Archive (English)

    Full Text Available NP_065184.2 chr1 Solution structure of the tandem four zf-C2H2 domain repeats of mu...rine GLI-Kruppel family member HKR3 c2dlqa_ chr1/NP_065184.2/NP_065184.2_holo_267-376.pdb psi-blast 274A,276

  19. 26 CFR 1.922-1 - Requirements that a corporation must satisfy to be a FSC or a small FSC.

    Science.gov (United States)

    2010-04-01

    ...) only if the foreign country is a party to (A) an exchange of information agreement under the Caribbean Basin Economic Recovery Act (Code section 274(h)((6)(C)), or (B) a bilateral income tax treaty with the... tax. For instance, dividend rights may not be used to direct dividends from exempt foreign trade...

  20. ADA (Trade Name) Adoption Handbook: A Program Manager’s Guide. Version 1.0.

    Science.gov (United States)

    1987-05-01

    Communications Rich Hilliard, MITRE Col. Paul Wickliffe, U.S. Army, Retired 1st Lt. Kurt W. Hoyt, U.S. Air Force William Wilder, U.S. Navy The...Manager AMCDE-SB 5001 Eisenhower Avenue Alexandria, Virginia 22333 (703) 274-9309 U.S. Navy: .Contact: U. Cmdr. Philp Myers, Acting Program Manager ,1

  1. Decomposition of Repetition Priming Processes in Word Translation

    Science.gov (United States)

    Francis, Wendy S.; Duran, Gabriela; Augustini, Beatriz K.; Luevano, Genoveva; Arzate, Jose C.; Saenz, Silvia P.

    2011-01-01

    Translation in fluent bilinguals requires comprehension of a stimulus word and subsequent production, or retrieval and articulation, of the response word. Four repetition-priming experiments with Spanish-English bilinguals (N = 274) decomposed these processes using selective facilitation to evaluate their unique priming contributions and factorial…

  2. Gclust Server: 200078 [Gclust Server

    Lifescience Database Archive (English)

    Full Text Available 200078 Caur_c105_g748 Cluster Sequences - 274 no annotation 1 1.00e-99 0.0 0.0 0.0 6.67 0.0 0.0 Show 2000...78 Cluster ID 200078 Sequence ID Caur_c105_g748 Link to cluster sequences Cluster Sequ

  3. Changes in household composition as determinant of changes in functional ability among old men and women

    DEFF Research Database (Denmark)

    Avlund, Kirsten; Due, Pernille; Holstein, Bjorn E;

    2002-01-01

    participated in the NORA follow-up study of 75-80 year-old men and women in Jyväskylä, Finland (N=243), Göteborg, Sweden (N=226), and Glostrup, Denmark (N=274). Functional ability was measured by tiredness and need for help in Physical and Instrumental Activities of Daily Living (PADL and IADL). Changes...

  4. Changes in the epidemiology of acute appendicitis and appendectomy in Danish children 1996-2004

    DEFF Research Database (Denmark)

    Andersen, S B; Paerregaard, A; Larsen, K

    2009-01-01

    PURPOSE: Aim of the study was to describe changes in the epidemiology of acute appendicitis in Danish children between 0-19 years of age for the period 1996-2004. METHODS: The study was based on discharge diagnoses taken from the Danish National Patient Registry of all 28 274 patients with a diag...

  5. 78 FR 31902 - 36(b)(1) Arms Sales Notification

    Science.gov (United States)

    2013-05-28

    ... Government of the Republic of Korea (ROK) has requested a possible sale of F-35 aircraft weapons. These... JUSTIFICATION Republic of Korea--F-35 Aircraft Weapons The Government of the Republic of Korea (ROK) has requested a possible sale of F-35 aircraft weapons. These aircraft weapons include the following: 274...

  6. AcEST: BP919007 [AcEST

    Lifescience Database Archive (English)

    Full Text Available =Saccharomyce... 30 7.4 sp|O08999|LTBP2_MOUSE Latent-transforming growth factor b...TVGIVCLSNVEE 274 SS TVG +C + E Sbjct: 276 KNSSGTVGPLCFQELNE 292 >sp|O08999|LTBP2_MOUSE Latent-transforming g

  7. Diatoms respire nitrate to survive dark and anoxic conditions

    DEFF Research Database (Denmark)

    Kamp, Anja; de Beer, Dirk; Nitsch, Jana L.

    2011-01-01

    Diatoms survive in dark, anoxic sediment layers for months to decades. Our investigation reveals a correlation between the dark survival potential of marine diatoms and their ability to accumulate NO3− intracellularly. Axenic strains of benthic and pelagic diatoms that stored 11–274 mM NO3− in th...

  8. Kuidas kirjutatakse ajalugu? / Roger Chartier ; interv. Marek Tamm

    Index Scriptorium Estoniae

    Chartier, Roger

    2007-01-01

    Kirjanduslikest tekstidest sotsiaalajaloo uurimisallikana, juhuse ja paratamatuse vahekorrast ajaloos ja Prantsuse revolutsiooni käsitlusest Pariisi õppe- ja teaduskeskuse Ecole des Hautes Etudes en Sciences Sociales professori R. Chartier'i teostes. Varem ilm.: Tekstid, praktikad ja lugejad : intervjuu Roger Chartier'ga // Chartier, Roger. Prantsuse revolutsiooni kultuurilised lätted. - Tallinn, 2002. - Lk. 274-290

  9. Mechanism of Ras Activation by TGFBeta

    Science.gov (United States)

    2002-07-01

    transcriptional activity of the vitamin D receptor (Yanagi- sawa et al, 1999). Smad3 and Smad4 can also associate with the acute myeloid leukemia family of... Ishii , S. (1999). ATF-2 is a common nuclear target of Smad and TAK1 pathways in transforming growth factor-ß signaling. J Biol Chem 274, 8949

  10. Quantitative analysis of HGF and EGF-dependent phosphotyrosine signaling networks

    DEFF Research Database (Denmark)

    Hammond, Dean E; Hyde, Russell; Kratchmarova, Irina;

    2010-01-01

    549 lung adenocarcinoma cells with EGF or HGF. In total, we obtained quantitative information for 274 proteins, which respond to either or both stimuli by >1.5 fold changes in enrichment, following immuno-precipitation with antiphosphotyrosine antibodies. The data reveal a high degree of overlap...

  11. Burnout and Competency Development in Pre-Service Teacher Training

    Science.gov (United States)

    Rodríguez-Hidalgo, Antonio J.; Calmaestra, Juan; Dios, Irene

    2014-01-01

    Introduction: The burnout syndrome negatively affects the students' academic performance. The relation between academic burnout and the self-perception of skills in initial teacher training is subjected to analysis. Method: A sample of 274 students (average age = 20,61 years old) from the Bachelor Degree in Early Childhood Education and the…

  12. The Utilisation of the Internet by Palestinian English Language Teachers Focusing on Uses, Practices and Barriers and Overall Contribution to Professional Development

    Science.gov (United States)

    Kabilan, Muhammad Kamarul; Rajab, Belal Mousa

    2010-01-01

    The paper describes a study designed to investigate the utilisation of the Internet by English Language teachers in Gaza focusing on uses, practices and barriers. A questionnaire was developed based on literature (Kabilan 2003; Kabilan & Mohamed Amin 2002) and was administered to 274 English language teachers in Gaza schools. Data reveal that…

  13. Prevalence of osteoporosis and factors associated with osteoporosis in women above 40 years in the Northern Part of Saudi Arabia

    Directory of Open Access Journals (Sweden)

    Anitha Oommen

    2014-02-01

    Conclusion: Prevalence of osteopenia is higher than osteoporosis in the Saudi women above 40 years in the Northern part of Saudi Arabia. The major cause of low BMD is lack of exercise even though there is a high prevalence of Vitamin D deficiency. [Int J Res Med Sci 2014; 2(1.000: 274-278

  14. Organisational age cultures : The interplay of chief executive officers age and attitudes toward younger and older employees

    NARCIS (Netherlands)

    Zacher, Hannes; Gielnik, Michael M.

    2014-01-01

    This article investigates the interactive effects of chief executive officer (CEO) age and CEO attitudes toward younger and older employees on organisational age cultures. Data was collected from 66 CEOs of small and medium-sized businesses and 274 employees. Results were consistent with expectation

  15. 10 CFR 150.4 - Communications.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Communications. 150.4 Section 150.4 Energy NUCLEAR... OFFSHORE WATERS UNDER SECTION 274 General Provisions § 150.4 Communications. Except where otherwise specified in this part, all communications and reports concerning the regulations in this part should...

  16. EST Table: FS917567 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available catabolic process) 10/09/28 71 %/272 aa ref|XP_001653664.1| ubiquitin fusion degradaton protein [Aedes aegy...pti] gb|EAT39129.1| ubiquitin fusion degradaton protein [Aedes aegypti] 10/09/12 65 %/274 aa FBpp0225719|Dvi

  17. Temperature, salinity and transmissivity data from the Alpha Helix in the Arctic Ocean, 2000 - 2004 (NODC Accession 0059005)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This is calibrated CTD downcast data from five Alpha Helix cruises: HX235, 8/1/2000 - 9/30/2000 HX250, 9/1/2001 - 9/30/2001 HX260, 6/1/2002 - 6/30/2002 HX274,...

  18. EST Table: FS835826 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available FS835826 E_FL_fmgV_49K21_R_0 10/09/28 32 %/274 aa ref|XP_001868268.1| thymus-specif...ic serine protease [Culex quinquefasciatus] gb|EDS26459.1| thymus-specific serine protease [Culex quinquefas

  19. Attachment Style, Social Support, and Coping as Psychosocial Correlates of Happiness in Persons with Spinal Cord Injuries

    Science.gov (United States)

    Wilson, Lisa; Catalano, Denise; Sung, Connie; Phillips, Brian; Chou, Chih-Chin; Chan, Jacob Yui Chung; Chan, Fong

    2013-01-01

    Objective: To examine the roles of attachment, social support, and coping as psychosocial correlates in predicting happiness in people with spinal cord injuries. Design: Quantitative descriptive research design using multiple regression and correlation techniques. Participants: 274 individuals with spinal cord injuries. Outcome Measures: Happiness…

  20. 75 FR 37707 - Administrative Process for Seizures and Forfeitures Under the Immigration and Nationality Act and...

    Science.gov (United States)

    2010-06-30

    ... Secretary 8 CFR Part 274 19 CFR Part 162 RIN 1651-AA58 Administrative Process for Seizures and Forfeitures Under the Immigration and Nationality Act and Other Authorities AGENCY: Office of the Secretary, DHS... of the HSA, both CBP and ICE retained authority to perform asset seizures and forfeitures under...

  1. EST Table: FS936452 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available ivity)|GO:0006508(proteolysis)|GO:0008270(zinc ion binding) 10/09/28 89 %/274 aa ref|NP_001036933.1| molting fluid... carboxypeptidase A [Bombyx mori] dbj|BAD60916.1| molting fluid carboxypeptidase A [Bombyx mori] 10/09

  2. New Measures of Heart-Rate Complexity: Effect of Chest Trauma and Hemorrhage

    Science.gov (United States)

    2010-05-01

    299. 6. Goldberger AL, West BJ. Applications of nonlinear dynamics to clinical cardiology . Ann NY Acad Sci. 1987;504:195–213. 7. Buchman TG...Palazzolo JA, Estafanous FG, Murray PA. Entropy measures of heart rate variation in conscious dogs . Am J Physiol. 1998;274:H1099–H1105. 34. West BJ

  3. Assessment of the Need to Perform Life-Saving Interventions Using Comprehensive Analysis of the Electrocardiogram and Artificial Neural Networks

    Science.gov (United States)

    2010-04-01

    physiological interpretation and clinical use. Task force of the european society of cardiology and the north american society of pacing and...rate variation in conscious dogs . Am J Physiol 274:H1099-1105, 1998. 38. Abu-Hanna A and Lucas PJ. Prognostic models in medicine. Ai and statistical

  4. 程序性死亡因子-1及其配体在强直性脊柱炎患者外周血的变化

    Institute of Scientific and Technical Information of China (English)

    张华; 骆方军; 周佳斌

    2010-01-01

    目的 探讨程序性死亡因子-1(PD-1,CD279)及其配体PD-L1(CD274)、PD-L2(CD273)在HLA-B27阳性和阴性强直性脊柱炎(AS)患者外周血的表达及意义.方法 采用流式细胞术检测HLA-B27阳性和阴性AS患者外周血CD8阳性淋巴细胞CD279、CD274和CD273的表达水平.结果 CD279、CD274和CD273在三组中的差异有统计学意义(0.05).结论 HLA-B27阳性AS患者CD279、CD274和CD273的表达水平比HLA-B27阴性AS患者高,可能与疾病的慢性化和迁延不愈有关.

  5. 78 FR 29155 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

    Science.gov (United States)

    2013-05-17

    ... Restricted, Columbus, 13000350 Logan County Booneville Commercial Historic District, E. side of 100 & 200...., Payette, 13000353 NEW JERSEY Essex County Pleasant Days, 274 Old Short Hills Rd., Millburn, 13000354... Spring Rd., Sterling, 13000363 Winchester Independent city Hawthorne and Old Town Spring, 610 &...

  6. Language Learning Strategies of Language e-Learners in Turkey

    Science.gov (United States)

    Solak, Ekrem; Cakir, Recep

    2015-01-01

    The purpose of this study was to determine the use of language learning strategies of e-learners and to understand whether there were any correlations between language learning strategies and academic achievement. Participants of the study were 274?e-learners, 132 males and 142 females, enrolled in an e-learning program from various majors and…

  7. Alliance for NanoHealth Competitive Research Program

    Science.gov (United States)

    2008-10-01

    439–445 2004. 34. L. C. Junqueira , W. Cossermelli, and R. Brentani, “Differential stain- ing of collagens type I, II and III by Sirius red and...polarization microscopy,” Arch. Histol. Jpn. 413, 267–274 1978. 35. L. C. Junqueira , G. Bignolas, and R. R. Brentani, “Picrosirius stain- ing plus

  8. Influenza virus resistance to oseltamivir: what are the implications?

    NARCIS (Netherlands)

    Fleming, D.M.; Elliot, A.J.; Meijer, A.; Paget, W.J.

    2009-01-01

    Influenza caused by an oseltamivir-resistant influenza A(H1N1) virus was widespread across Europe during the 2007–08 winter. About 25% of A(H1N1) viruses tested in the European Influenza Surveillance Scheme (EISS) were resistant with an H274Y mutation in the neuraminidase glycoprotein. Early indicat

  9. Letter to the Editor

    Directory of Open Access Journals (Sweden)

    Thomas K. Karikari

    2015-02-01

    Full Text Available This article is a reaction to a previously published article in the Journal of Microbiology & Biology Education, “Gamification of the Laboratory Experience to Encourage Student Engagement” by Kevin Drace (JMBE 14(2:273–274, 2013.

  10. Adaptive and Challenged Parenting among African American Mothers: Parenting Profiles Relate to Head Start Children's Aggression and Hyperactivity

    Science.gov (United States)

    Carpenter, Johanna L.; Mendez, Julia

    2013-01-01

    Research Findings: This study used a within-group research design and person-centered analytic methods to identify multidimensional profiles of parenting styles, parenting practices, and related emotional factors in a sample of 274 African American mothers recruited from Head Start programs in the northeastern and southeastern United States.…

  11. Performance of first-trimester combined test for Down syndrome in different maternal age groups: reason for adjustments in screening policy?

    NARCIS (Netherlands)

    Engels, Martin; Heijboer, A.C.; Blankenstein, M.A.; Vugt, J.M.G. van

    2011-01-01

    OBJECTIVE: To evaluate the performance of the first-trimester combined test (FCT) in different maternal age groups and to discuss whether adjustments in screening policies should be made. METHODS: In this retrospective study data (n = 26 274) from a fetal medicine center on FCT (maternal age, fetal

  12. A Neural Network for Estimation of Aortic Pressure from the Radial Artery Pressure Pulse

    Science.gov (United States)

    2001-10-25

    from periphery to artery: a model based study, American Journal of Physiology, 1998,274:43, pp H1386-92 [9] C. Chen, E. Nevo , B Fetics, P Pak, F, Yin, L...36. [10] B Fetics, E Nevo , C. Chen, D Kass, Parametric model derivation of transfer function for noninvasive estimation of aortic pressure by radial

  13. Resting Metabolic Rate is Not Reduced in Obese Adults With Down Syndrome

    Science.gov (United States)

    Fernhall, Bo; Figueroa, Arturo; Collier, Scott; Goulopoulou, Styliani; Giannopoulou, Ifigenia; Baynard, Tracy

    2005-01-01

    Resting metabolic rate (RMR) of 22 individuals with Down syndrome was compared to that of 20 nondisabled control individuals of similar age (25.7 and 27.4 years, respectively). Using a ventilated hood system, we measured RMR in the early morning after an overnight fast. Peak aerobic capacity Volume of Oxygen (VO2 peak) and body composition were…

  14. Disease: H00196 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available ers of purine and pyrimidine metabolism. Mol Genet Metab 86:25-33 (2005) PMID:10066814 Ahmed M, Taylor W, Sm...normal human phosphoribosylpyrophosphate synthetase. J Biol Chem 274:7482-8 (1999) PMID:8702702 Becker MA, Taylor

  15. GETDB: 103581 [GETDB

    Lifescience Database Archive (English)

    Full Text Available ble 1954 1 Request - muscle subset weak ubiquitous sg internal lethal P{GawB}NP0297 comment1:A, comment...NP0297 Original Comments comment1:A, comment2:74C1 Disc (Image) d1 Disc (number) 1 Embryo (Image) - Embryo (

  16. Victimization and suicidality among Dutch lesbian, gay, and bisexual youths

    NARCIS (Netherlands)

    van Bergen, D.D.; Bos, H.M.W.; van Lisdonk, J.; Keuzenkamp, S.; Sandfort, T.G.M.

    2013-01-01

    We examined Netherlands Institute for Social Research data, collected between May and August 2009, on 274 Dutch lesbian, gay, and bisexual youths. The data showed that victimization at school was associated with suicidal ideation and actual suicide attempts. Homophobic rejection by parents was also

  17. Victimization and Suicidality Among Dutch Lesbian, Gay, and Bisexual Youths

    NARCIS (Netherlands)

    van Bergen, Diana; Bos, Henny M.W.; van Lisdonk, jantine; Keuzenkamp, S; Sandfort, T.G.M

    2013-01-01

    We examined Netherlands Institute for Social Research data, collected between May and August 2009, on 274 Dutch lesbian, gay, and bisexual youths. The data showed that victimization at school was associated with suicidal ideation and actual suicide attempts. Homophobic rejection by parents was also

  18. Image files of planarians analyzed by in situ hybridication and immunohistochemical staining - Plabrain DB | LSDB Archive [Life Science Database Archive metadata

    Lifescience Database Archive (English)

    Full Text Available ans or planarian head regions in the regeneration process. Images are displayed in A list of image files of ...file File name: planaria_image.zip File URL: ftp://ftp.biosciencedbc.jp/archive/p...labrain-db/LATEST/planaria_image.zip File size: 2.74MB Simple search URL - Data acquisition method Whole-mou

  19. DNAJC6 Mutations Associated With Early-Onset Parkinson's Disease

    NARCIS (Netherlands)

    Olgiati, Simone; Quadri, Marialuisa; Fang, Mingyan; Rood, Janneke P. M. A.; Saute, Jonas A.; Chien, Hsin Fen; Bouwkamp, Christian G.; Graafland, Josja; Minneboo, Michelle; Breedveld, Guido J.; Zhang, Jianguo; Verheijen, Frans W.; Boon, Agnita J. W.; Kievit, Anneke J. A.; Jardim, Laura Bannach; Mandemakers, Wim; Barbosa, Egberto Reis; Rieder, Carlos R. M.; Leenders, Klaus L.; Wang, Jun; Bonifati, Vincenzo

    ObjectiveDNAJC6 mutations were recently described in two families with autosomal recessive juvenile parkinsonism (onset age MethodsThe DNAJC6 open reading frame was analyzed in 274 patients with early-onset sporadic or familial PD. Selected variants were followed up by cosegregation, homozygosity

  20. 20 CFR 655.920 - Definitions.

    Science.gov (United States)

    2010-04-01

    ... situated employees in the occupation at the worksite at the time of employment. Administrative Law Judge... students pursuant to Immigration and Naturalization Service regulations at 8 CFR parts 214 and 274a... a course of study at an established institution of learning or other recognized place of study...

  1. Science Teachers' Perception on Multicultural Education Literacy and Curriculum Practices

    Science.gov (United States)

    Huang, Hsiu-Ping; Cheng, Ying-Yao; Yang, Cheng-Fu

    2017-01-01

    This study aimed to explore the current status of teachers' multicultural education literacy and multicultural curriculum practices, with a total of 274 elementary school science teachers from Taitung County as survey participants. The questionnaire used a Likert-type four-point scale which content included the teachers' perception of…

  2. X-ray crystal structure of divalent metal-activated ß-xyloisdase, RS223BX

    Science.gov (United States)

    We report the first X-ray structure of a glycoside hydrolase family 43 ß-xylosidase, RS223BX, which is strongly activated by the addition of divalent metal cations. The 2.69 Å structure reveals that the Ca2+ cation is located at the back of the active site pocket. The Ca2+ coordinates to H274 to sta...

  3. Diatoms respire nitrate to survive dark and anoxic conditions

    DEFF Research Database (Denmark)

    Kamp, Anja; de Beer, Dirk; Nitsch, Jana L.

    2011-01-01

    Diatoms survive in dark, anoxic sediment layers for months to decades. Our investigation reveals a correlation between the dark survival potential of marine diatoms and their ability to accumulate NO3− intracellularly. Axenic strains of benthic and pelagic diatoms that stored 11–274 mM NO3− in th...

  4. Functional Characterization of Two Novel Human Prostate Cancer Metastasis Related Genes

    Science.gov (United States)

    2008-02-01

    capture microdissection. Science. 274:998- 1001, 1996. 13 31. Listisyn, N, Listisyn, N, and Wigler, M. Cloning the differences between tow ...phytohemaglutinin and phorbol 12-myristate 13- acetate . Anal. Biochem., 240:90-97, 1996. 36. Wang, Z., and Brown, D. D. A gene expression screen. (1991

  5. File list: NoD.Neu.05.AllAg.Brain [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available NoD.Neu.05.AllAg.Brain mm9 No description Neural Brain ERX161927,ERX161926,ERX16192...274,SRX298040,ERX402277,ERX402292,ERX402281 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/NoD.Neu.05.AllAg.Brain.bed ...

  6. Draft Genome Sequences of Five Yersinia pseudotuberculosis ST19 Isolates and One Isolate Variant.

    Science.gov (United States)

    Platonov, Mikhail E; Blouin, Yann; Evseeva, Vera V; Afanas'ev, Maxim V; Pourcel, Christine; Balakhonov, Sergey V; Vergnaud, Gilles; Anisimov, Andrey P

    2013-04-11

    We report the first draft genome sequences of five Yersinia pseudotuberculosis isolates of sequence type (ST) 19 and of a variant from one of the five isolates. The total length of assemblies ranged from 4,226,485 bp to 4,274,148 bp, including between 3,808 and 3,843 predicted coding sequences.

  7. Special Operations Forces and Elusive Enemy Ground Targets: Lessons from Vietnam and the Persian Gulf War

    Science.gov (United States)

    2001-01-01

    Enemy Ground Targets team members to fire their weapons as they were lifted from the forest floor . 4 9 Moving through and searching the jungle...MACVSOG headquarters, and as bartenders and waitresses at MACVSOG compounds, where they 61Prados, Blood Road, p. 274. Yearly totals for SHINING BRASS

  8. HISTORICAL GEOLOGY & STRATIGRAPHY

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    <正>20042202 Chen Gang (Department of Geology, Northwest University, Xi’an, Shaanxi); Zhao Zhongyuan Natural of Pre-Mesozoic Tectono-Lithostratigraphic Units of North -Huaiyang Belt and Implication for Tectonic Evolution (Journal of Northwest University (Natural Science Edition), ISSN 1000-274X, CN61-1072/N, 33(5), 2003, p. 595 -598, 1 table, 14 refs. )

  9. 40 CFR 60.276a - Recordkeeping and reporting requirements.

    Science.gov (United States)

    2010-07-01

    ...: (1) Facility name and address; (2) Plant representative; (3) Make and model of process, control device, and continuous monitoring equipment; (4) Flow diagram of process and emission capture equipment... at values exceeding ±15 percent of the value established under § 60.274a(c) or operation at flow...

  10. 40 CFR 60.276 - Recordkeeping and reporting requirements.

    Science.gov (United States)

    2010-07-01

    ...) Plant representative; (3) Make and model of process, control device, and continuous monitoring equipment; (4) Flow diagram of process and emission capture equipment including other equipment or process(es... values exceeding ±15 percent of the value established under § 60.274(c) or operation at flow rates lower...

  11. Domain Modeling: NP_001018001.1 [SAHG[Archive

    Lifescience Database Archive (English)

    Full Text Available NP_001018001.1 chr1 CRYSTAL STRUCTURE OF TROPOMYOSIN AT 7 ANGSTROMS RESOLUTION IN THE SPERMINE-INDUCED CRYST...AL FORM c1c1gd_ chr1/NP_001018001.1/NP_001018001.1_apo_3-274.pdb psi-blast 0 ...

  12. Domain Modeling: NP_059431.1 [SAHG[Archive

    Lifescience Database Archive (English)

    Full Text Available NP_059431.1 chr19 Crystal Structure of Autoinhibited Form of Grp1 Arf GTPase Exchan...ge Factor c2r0db_ chr19/NP_059431.1/NP_059431.1_holo_49-390.pdb blast 268K,270G,271G,272G,273R,274V,276T,278

  13. Image Descriptors for Displays

    Science.gov (United States)

    1977-02-01

    13, 274 (1969). 15. E. E. Smith and K. T. Spoehr, ’The Perception of Printea inglish," in SB. Kantowitz , ed., ihumr Information Processing: Tutorials...Processing Research," in B. Kantowitz , ed., Human Information Processing: Tutorials in Performance and Cognition (Halsted Press, New York, 1974). 26. J. J

  14. Disease: H00289 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available Bourc'his D Genetics and epigenetics of hydatidiform moles. Nat Genet 38:274-6 (2006) PMID:19309689 (gene) ...inflammatory and apoptotic pathways. Cancer NALP7 [HSA:199713] ICD-9: 630 OMIM: 231090 PMID:17204043 (gene) Slim R, Mehio A The genet...ics of hydatidiform moles: new lights on an ancient disease. Clin Genet 71:25-34 (2

  15. Do Physical and Relational Aggression Explain Adolescents' Friendship Selection? The Competing Roles of Network Characteristics, Gender, and Social Status

    NARCIS (Netherlands)

    Dijkstra, Jan Kornelis; Berger, Christian; Lindenberg, Siegwart

    2011-01-01

    The role of physical and relational aggression in adolescents' friendship selection was examined in a longitudinal sample of 274 Chilean students from 5th and 6th grade followed over 1 year. Longitudinal social network modeling (SIENA) was used to study selection processes for aggression while influ

  16. An Investigation of College Students' Learning Styles in the US and China

    Science.gov (United States)

    Zhan, Ginny Q.; Moodie, Douglas R.; Sun, Yanmin; Wang, Bailing

    2013-01-01

    This research project explores learning styles of college students in the US and China. The Grasha-Reichmann Student Learning Style Scale, designed to measure how college students view their learning, was used as the main instrument for the current study. A total of 511 college students, 274 from the US and 237 from China, participated in this…

  17. Revision of the Lauraceae III. The genera Aiouea, Systemonodaphne, Urbanodendron, Mezilaurus; additions and corrections to Licaria and Cryptocarya

    NARCIS (Netherlands)

    Kostermans, A.J.G.H.

    1938-01-01

    Aiouea Aublet, Hist. Guian. I (1775), p. 310; III, t. 120; Scopoli, Introductio Hist. nat. (Pragae 1777), p. 107, n. 277; Lamarck, Encyclop. méthod. I (1783), p. 72 (Ajúvea); Poiret, Encycl., Suppl. I (1890), p. 274, III (1893), p. 317; Illustrat. Genr. II, p. 395 et 367, t. 360; Jussieu, Genera (17

  18. Lexical Development in Korean: Vocabulary Size, Lexical Composition, and Late Talking

    Science.gov (United States)

    Rescorla, Leslie; Lee, Youn Mi Cathy; Oh, Kyung Ja; Kim, Young Ah

    2013-01-01

    Purpose: In this study, the authors aimed to compare vocabulary size, lexical composition, and late talking in large samples of Korean and U.S. children ages 18-35 months. Method: Data for 2,191 Korean children (211 children recruited "offline" through preschools, and 1,980 recruited "online" via the Internet) and 274 U.S.…

  19. An Analysis of the Relationship between Organizational Communication and Organizational Cynicism According to Teachers' Perceptions in Turkey

    Science.gov (United States)

    Ayik, Ahmet

    2015-01-01

    In this study, the relations between organizational communication and organizational cynicism have been analyzed. The sample of the study consists of 274 teachers working in state secondary schools in Palandöken County of Erzurum, in 2013-2014 academic year. "Organizational Cynicism Scale" and "Organizational Communication…

  20. 10 CFR 150.11 - Critical mass.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Critical mass. 150.11 Section 150.11 Energy NUCLEAR... OFFSHORE WATERS UNDER SECTION 274 Exemptions in Agreement States § 150.11 Critical mass. (a) For the purposes of this part, special nuclear material in quantities not sufficient to form a critical mass...

  1. Burnout and Competency Development in Pre-Service Teacher Training

    Science.gov (United States)

    Rodríguez-Hidalgo, Antonio J.; Calmaestra, Juan; Dios, Irene

    2014-01-01

    Introduction: The burnout syndrome negatively affects the students' academic performance. The relation between academic burnout and the self-perception of skills in initial teacher training is subjected to analysis. Method: A sample of 274 students (average age = 20,61 years old) from the Bachelor Degree in Early Childhood Education and the…

  2. Complete genome sequence of Lactobacillus plantarum WCFS1

    NARCIS (Netherlands)

    Kleerebezem, Michiel; Boekhorst, Jos; Kranenburg, Richard van; Molenaar, Douwe; Kuipers, Oscar P.; Leer, Rob; Tarchini, Renato; Peters, Sander A.; Sandbrink, Hans M.; Fiers, Mark W.E.J.; Stiekema, Willem; Klein Lankhorst, René M.; Bron, Peter A.; Hoffer, Sally M.; Nierop Groot, Masja N.; Kerkhoven, Robert; Vries, Maaike de; Ursing, Björn; Vos, Willem M. de; Siezen, Roland J.

    2003-01-01

    The 3,308,274-bp sequence of the chromosome of Lactobacillus plantarum strain WCFS1, a single colony isolate of strain NCIMB8826 that was originally isolated from human saliva, has been determined, and contains 3,052 predicted protein-encoding genes. Putative biological functions could be assigned t

  3. Domain Modeling: NP_008881.2 [SAHG[Archive

    Lifescience Database Archive (English)

    Full Text Available NP_008881.2 chrX Crystal Structure of Rat Synapsin I C Domain Complexed to Ca.ATP (...Form 1) c1px2b_ chrX/NP_008881.2/NP_008881.2_holo_113-417.pdb blast 188H,225K,267V,269K,273A,274H,275S,276G,

  4. Evaluation of the innate immune response of Angus heifers with genetic marker variation for intramuscular fat deposition following a lipopolysaccharide challenge

    Science.gov (United States)

    This study evaluated the effect of genetic selection for markers related to marbling deposition in Angus heifers on the immune response following a lipopolysaccharide (LPS) challenge. Fall-born heifers (n = 19; ~7 months of age, 274 +/- 24 kg) with genetic variation for marbling were utilized inclu...

  5. Dragonair- Year-on-Year Rises Continue For Passengers And Cargo

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    @@ Passenger numbers at Dragonair rose 13.2% while cargo volumes climbed 23.9%in April compared with the same month in 2004. The airline flew 431,860 passengers last month, 50,274 more than one year ago,and 7.3% up on March.

  6. In vitro fertilization (IVF) using semi-defined culture conditions from low or high antral follicle count pubertal beef heifers

    Science.gov (United States)

    To compare the in vitro fertilization (IVF) and production (IVP) of embryos from low and high antral follicle count (AFC) heifers, AFC were determined on 106 heifers using transrectal ultrasonography. Ten heifers with the lowest AFC (avg. 13.2) and 10 heifers with the highest AFC (avg. 27.4) with ev...

  7. Latino Adolescents' Mental Health: Exploring the Interrelations among Discrimination, Ethnic Identity, Cultural Orientation, Self-Esteem, and Depressive Symptoms

    Science.gov (United States)

    Umana-Taylor, Adriana J.; Updegraff, Kimberly A.

    2007-01-01

    Guided by a risk and resilience framework, the current study used cross-sectional data to examine the degree to which Latino adolescents' (N=274; M age=16.3; 47.1% female) self-esteem, ethnic identity, and cultural orientations mediated or moderated the relation between perceived discrimination and depressive symptoms. Utilizing a multiple group…

  8. Planck intermediate results XXXI. Microwave survey of Galactic supernova remnants

    DEFF Research Database (Denmark)

    Arnaud, M.; Ashdown, M.; Atrio-Barandela, F.;

    2016-01-01

    The all-sky Planck survey in 9 frequency bands was used to search for emission from all 274 known Galactic supernova remnants. Of these, 16 were detected in at least two Planck frequencies. The radio-through-microwave spectral energy distributions were compiled to determine the mechanism for micr...

  9. Resting Metabolic Rate is Not Reduced in Obese Adults With Down Syndrome

    Science.gov (United States)

    Fernhall, Bo; Figueroa, Arturo; Collier, Scott; Goulopoulou, Styliani; Giannopoulou, Ifigenia; Baynard, Tracy

    2005-01-01

    Resting metabolic rate (RMR) of 22 individuals with Down syndrome was compared to that of 20 nondisabled control individuals of similar age (25.7 and 27.4 years, respectively). Using a ventilated hood system, we measured RMR in the early morning after an overnight fast. Peak aerobic capacity Volume of Oxygen (VO2 peak) and body composition were…

  10. The Study of Relationship between Organizational Culture and Organizational Belonging in Employees of Varamin County Office of Education

    Science.gov (United States)

    Tabatabaee, Seyed Mahmoud; Koohi, Amirhasan; Ghandali, Abbas; Tajik, Tayebeh

    2016-01-01

    The purpose of the present research is to study the relationship between organizational culture and organizational belonging among employees of Varamin County ministry of education. This is a descriptive-survey study. The statistical population is consisted of all 274 official and contract employees of ministry of education in Varamin County of…

  11. Gclust Server: 19387 [Gclust Server

    Lifescience Database Archive (English)

    Full Text Available 19387 Rso_RSc3183 Cluster Sequences Related Sequences(274) 846 PROBABLE HEMAGGLUTIN...IN-RELATED SIGNAL PEPTIDE PROTEIN 5 1.00e-06 14.29 0.0 0.0 6.67 3.23 0.0 Show 19387 Cluster ID 19387 Sequenc

  12. Research funding systems in Australia, New Zealand and the UK

    DEFF Research Database (Denmark)

    Lewis, Jenny; Ross, S

    2011-01-01

    . This article reports on a study involving interviews with 274 academics at universities in Australia (Melbourne), New Zealand (Auckland) and the UK (Birmingham). Perceptions of the three research funding systems demonstrated significant differences across universities, and some interesting gender and seniority...

  13. Attacks by “Anonymous” WikiLeaks Proponents not Anonymous

    NARCIS (Netherlands)

    Pras, Aiko; Sperotto, Anna; Moura, Giovane C.M.; Drago, Idilio; Barbosa, Rafael; Sadre, Ramin; Schmidt, Ricardo; Hofstede, Rick

    2010-01-01

    On November 28, 2010, the world started watching the whistle blower website WikiLeaks to begin publishing part of the 250,000 US Embassy Diplomatic cables. These confidential cables provide an insight on U.S. international affairs from 274 different embassies, covering topics such as analysis of hos

  14. CONSUMPTION OF FRUITS AMONG STUDENTS: A CASE OF A ...

    African Journals Online (AJOL)

    ICD-UGL

    2012-04-02

    Apr 2, 2012 ... consume fruits as per the recommended daily intake. This study ... fibrous part. Variables such as taste, time-wasting, religious belief, knowledge, ill- ..... and women. 8.10 5.70 27.4 .... New York: Guinness Media Inc,. 1997: 65.

  15. Gclust Server: 44443 [Gclust Server

    Lifescience Database Archive (English)

    Full Text Available 44443 ATH_AT4G08460_15236507 Cluster Sequences Related Sequences(37) 274 unknown pr...otein 2 1.00e-45 28.57 0.0 0.0 0.0 0.0 0.0 Show 44443 Cluster ID 44443 Sequence ID ATH_AT4G08460_15236507 Li

  16. Organisational age cultures : The interplay of chief executive officers age and attitudes toward younger and older employees

    NARCIS (Netherlands)

    Zacher, Hannes; Gielnik, Michael M.

    2014-01-01

    This article investigates the interactive effects of chief executive officer (CEO) age and CEO attitudes toward younger and older employees on organisational age cultures. Data was collected from 66 CEOs of small and medium-sized businesses and 274 employees. Results were consistent with expectation

  17. HLA-Restricted CTL That Are Specific for the Immune Checkpoint Ligand PD-L1 Occur with High Frequency in Cancer Patients

    DEFF Research Database (Denmark)

    Munir, Shamaila; Andersen, Gitte Holmen; Met, Özcan;

    2013-01-01

    PD-L1 (CD274) contributes to functional exhaustion of T cells and limits immune responses in patients with cancer. In this study, we report the identification of an human leukocyte antigen (HLA)-A2-restricted epitope from PD-L1, and we describe natural, cytolytic T-cell reactivity against PD-L1...

  18. 77 FR 6971 - Establishment of User Fees for Filovirus Testing of Nonhuman Primate Liver Samples

    Science.gov (United States)

    2012-02-10

    ... occurred, mostly in Central Africa, and all have been associated with high (45-90%) case-fatality rates in... surviving NHPs that exhibit signs of possible filovirus infection before the cohort is released from... responsibilities among the various levels of government.'' H. Plain Language Act of 2010 Under Public Law 111-274...

  19. Furin proteolytically processes the heparin-binding region of extracellular superoxide dismutase

    DEFF Research Database (Denmark)

    Bowler, Russell P; Nicks, Mike; Olsen, Dorte Aa

    2002-01-01

    . (1999) J. Biol. Chem. 274, 14818-14822). By using mammalian cell lines, we have now determined that removal of the heparin-binding region occurs after passage through the Golgi network but before being secreted into the extracellular space. Specific protease inhibitors and overexpression...

  20. Attachment Style, Social Support, and Coping as Psychosocial Correlates of Happiness in Persons with Spinal Cord Injuries

    Science.gov (United States)

    Wilson, Lisa; Catalano, Denise; Sung, Connie; Phillips, Brian; Chou, Chih-Chin; Chan, Jacob Yui Chung; Chan, Fong

    2013-01-01

    Objective: To examine the roles of attachment, social support, and coping as psychosocial correlates in predicting happiness in people with spinal cord injuries. Design: Quantitative descriptive research design using multiple regression and correlation techniques. Participants: 274 individuals with spinal cord injuries. Outcome Measures: Happiness…

  1. Proceedings of the STRESS Data Review Meeting, 29-30 November 1977

    Science.gov (United States)

    1978-06-01

    The scien- tific director viewed the C-6 display, and received information orally from the wing-site operators concerning the gross structure of the...yF"F . (10) mn m m n 274 „jg-fm, Expresion Eq. (10) corresponds to what has been called "seed growth." Another class of gradient-drift

  2. An Epithelial-Derived, Integral Membrane, Kunitz-Type Serine Protease Inhibitor in Breast Cancer

    Science.gov (United States)

    2005-08-01

    an epithelial membrane serine protease. J Biol Chein 275: 36720-36725, 2000. prevents15. Lin CY, Anders J, Johnson M, and Dickson RB. Purification and...functions properly, thus trypsin-like activity. J Biol Chein 274: 18231--18236, 1999. 0 avoiding harmful effects. 17. Lin CY, Wang JK, Torri J, Dou L, Sang

  3. Screening for Small Molecules That Disrupt IAP-Caspases Binding to Activate Caspases and Induce Apoptosis in Breast Cancers

    Science.gov (United States)

    2005-09-01

    Zou H and Fesik SW. (2004). Yuan J. (2005). Science, 307, 935-939. J. Med Chein ., 47, 4417-4426. Cao C, Mu Y, Hallahan DE and Lu B. (2004). Oncogene...Schuler M, Echeverri F and Green DR. (1999). Harran PG. (2004). Science, 305, 1471-1474. J. Biol. Chein ., 274, 30651-30656. Lima RT, Martins LM, Guimaraes

  4. Results of the Cord Blood Transplantation Study (COBLT) : clinical outcomes of unrelated donor umbilical cord blood transplantation in pediatric patients with hematologic malignancies

    NARCIS (Netherlands)

    Kurtzberg, Joanne; Prasad, Vinod K.; Carter, Shelly L.; Wagner, John E.; Baxter-Lowe, Lee Ann; Wall, Donna; Kapoor, Neena; Guinan, Eva C.; Feig, Stephen A.; Wagner, Elizabeth L.; Kernan, Nancy A.

    2008-01-01

    Outcomes of unrelated donor cord blood transplantation in 191 hematologic malignancy children (median age, 7.7 years; median weight, 25.9 kg) enrolled between 1999 and 2003 were studied (median follow-up, 27.4 months) in a prospective phase 2 multicenter trial. Human leukocyte antigen (HLA) matching

  5. 75 FR 81831 - Supplemental Nutrition Assistance Program, Regulation Restructuring: Issuance Regulation Update...

    Science.gov (United States)

    2010-12-29

    ... 7 CFR part 274 and was published at 75 FR 18377 on April 12, 2010. Dated: November 24, 2010. Julia... coupon issuance and EBT pilot regulations that are no longer applicable, revise regulatory language to... Food and Nutrition Service adopted as a final rule the direct final rule published at 75 FR 18377...

  6. Signature splitting and quasiparticle alignment in the yrast band of Ta-165

    NARCIS (Netherlands)

    Roux, DG; Fetea, MS; Gueorguieva, E; Babu, BRS; Newman, RT; Lawrie, JJ; Fearick, R; Aschman, DG; Beetge, R; Benatar, M; Mabala, GK; Mullins, SM; Murray, SHT; Naguleswaran, S; Rigollet, C; Sharpey-Schafer, JF; Smit, FD; Whittaker, WJ

    Excited states in Ta-165 were populated in the Nd-142(Al-27,4n)Ta-165 and Pr-141(Si-28,4n)Ta-165 reactions and investigated using the AFRODITE array. The yrast rotational decay sequence up to spin 53/2(-) is identified and assigned to the [514]9/2(-) configuration. The nuclear shape is investigated

  7. Pedological ~cterization, Clay Mine:at~ and .~cation of,

    African Journals Online (AJOL)

    formulation of proper national land management. Hill whose map .... 7. 3. 274. 180. 234. 1284. 1964 25. 122. 140. 254. 37. 10. 5. 16 . 139. 7. 132. 987 ...... isohyperthermic SMR,~QC decreases Ir': T •. -..... t'. ~ ,. ..... Ithaca, New York. Watanabe ...

  8. Gclust Server: 176060 [Gclust Server

    Lifescience Database Archive (English)

    Full Text Available 176060 DPTM_GSPATP00024285001 Cluster Sequences - 274 no annotation 1 1.00e-99 0.0 ...11.11 0.0 0.0 0.0 0.0 Show 176060 Cluster ID 176060 Sequence ID DPTM_GSPATP00024285001 Link to cluster seque

  9. Heart Rate Variability, Catecholamine and Hemodynamic Responses During Rest and Stress in Coronary Artery Disease Patients: The PIMI Study

    Science.gov (United States)

    2007-01-31

    blinded analysis. Data Analyses SPSS version 12.01 software package from SPSS Inc. (2003) was used for the data analytical procedures. Key...patients undergoing electrocardiographic Holter monitoring. J Am Coll Cardiol, 27(4), 847-852. Ramachandruni, S., Fillingim, R. B., McGorray, S. P

  10. Knowledge workers' creativity and the role of the physical work environment

    NARCIS (Netherlands)

    J. Dul (Jan); C. Ceylan (Canan); F.P.H. Jaspers (Ferdinand)

    2011-01-01

    textabstractABSTRACT The present study examines the effect of the physical work environment on the creativity of knowledge workers, compared with the effects of creative personality and the social-organizational work environment. Based on data from 274 knowledge workers in 27 SMEs, we conclude that

  11. 75 FR 76485 - Certain Electronic Paper Towel Dispensing Devices and Components Thereof; Notice of Commission...

    Science.gov (United States)

    2010-12-08

    ...,182,289; and 7,387,274. 75 FR 28651-2 (May 21, 2010). The complainant named as respondents Kruger Products LP of Mississauga, Canada (``Kruger''); KTG USA LP of Memphis, Tennessee (``KTG USA''); Stefco...: (1) To correct the corporate name of NetPak Chicago; (2) to redefine ``Kruger'' to ``Kruger...

  12. AcEST: DK959385 [AcEST

    Lifescience Database Archive (English)

    Full Text Available KL 63 Query: 274 GYANANIYVCEDERCPRPMCYKAYGSGKEDSPLCDIPGFENARMKLLRHVSFVDSPGQDI 453...CPRPMCYKAYGSGKEDSPLCDIPGFENARMKLLRHVSFVDSPGQDILMATMLNG 477 +D C RP CY++ GS D DIPG KL+RHVSFVD PG DILMATMLNG S...ANA IY Sbjct: 30 PLSHEVISRQATINIGTIGHVAHGKSTVVKAISGVHTVRFKNELERNITIKLGYANAKIY 89 Query: 298 VCEDERCPRPMCYKAYGSGKEDSPLCDIPGFENARM...EDERCPRPMCYKAYGSGKEDSPLCDIPGFENARMKLLRHVSFVDSPGQDILMATMLNG 477 +D CPRP CY++ GS D DIPG KL+RHVSFVD PG DILMATML...GYANAKIY 89 Query: 298 VCEDERCPRPMCYKAYGSGKEDSPLCDIPGFENARMKLLRHVSFVDSPGQDILMATMLNG 477 +D CPRP CY++ GS D DI

  13. The Application of Linear Prediction to Sequential Classification of Radar Target Signatures

    Science.gov (United States)

    1976-03-25

    treated in the earlier portion of this report. However, generalization serves only to complicate the algebra and adds very little to the understanding...Wiley, New York, 1958). 9. E. A. Robinson, Statistical Communication and Detection (Hafner Publishing Company, New York, 1967), pp. 274-279. i0. J. Durbin

  14. 40 CFR 721.4620 - Dialkylamino alkanoate metal salt.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Dialkylamino alkanoate metal salt. 721... Substances § 721.4620 Dialkylamino alkanoate metal salt. (a) Chemical substances and significant new uses... salt (P-90-274), is subject to reporting under this section for the significant new uses described in...

  15. AcEST: BP921654 [AcEST

    Lifescience Database Archive (English)

    Full Text Available r OS=Yersinia pestis GN=hmuR P... 30 7.2 sp|Q20911|CUBN_CAEEL Probable cubilin OS=Caenorhabditis elegans ......L+ E + T +Q YYS + I+ P+ + Sbjct: 274 PSSTNVMTNRSTIQRDAQLRYNIKPLDQEWLNAT-AQVYYSEVEINARPQGS 324 >sp|Q20911|CUBN_CAEEL Probable cubilin

  16. 41 CFR 101-27.406 - Disposition of stock.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true Disposition of stock. 101-27.406 Section 101-27.406 Public Contracts and Property Management Federal Property Management Regulations System FEDERAL PROPERTY MANAGEMENT REGULATIONS SUPPLY AND PROCUREMENT 27-INVENTORY MANAGEMENT 27.4...

  17. Revision of the Lauraceae III. The genera Aiouea, Systemonodaphne, Urbanodendron, Mezilaurus; additions and corrections to Licaria and Cryptocarya

    NARCIS (Netherlands)

    Kostermans, A.J.G.H.

    1938-01-01

    Aiouea Aublet, Hist. Guian. I (1775), p. 310; III, t. 120; Scopoli, Introductio Hist. nat. (Pragae 1777), p. 107, n. 277; Lamarck, Encyclop. méthod. I (1783), p. 72 (Ajúvea); Poiret, Encycl., Suppl. I (1890), p. 274, III (1893), p. 317; Illustrat. Genr. II, p. 395 et 367, t. 360; Jussieu, Genera

  18. 78 FR 4766 - Adoption of Updated EDGAR Filer Manual

    Science.gov (United States)

    2013-01-23

    ... COMMISSION 17 CFR Parts 232, 239, 249, 269, 274 Adoption of Updated EDGAR Filer Manual AGENCY: Securities and...) Filer Manual and related rules to reflect updates to the EDGAR system. The revisions are being made...: Effective Date: January 23, 2013. The incorporation by reference of the EDGAR Filer Manual is approved...

  19. Defense Logistics Agency Disposition Services as a Supply Source: A DoD-Wide Opportunity

    Science.gov (United States)

    2013-07-01

    Inventory USMC Requisitions Nomenclature Unit Price 8465011150026 235 2032 Canteen , Water $5.08 5660002701510 1139 1800 Post, Fence, Metal $6.75...7503 500 Cover, Water Canteen $5.85 8465011178699 460 498 Bag, Duffel $22.90 5310012349416 3598 470 Washer, Flat $0.01 2590015762424 329 274 Cutter

  20. Development of Biomarkers for Assessing In Situ RDX Biodegradation Potential

    Science.gov (United States)

    2010-02-01

    restriction fragment patterns (TRFPs), a rapid, PCR-based method for the comparison of complex bacterial communities. Journal of Microbiological Methods 31,135...chain reaction method for monitoring RDX-degrading bacteria based on the xplA functional gene. Journal of Microbiological Methods 68,267-274

  1. Kuidas kirjutatakse ajalugu? / Roger Chartier ; interv. Marek Tamm

    Index Scriptorium Estoniae

    Chartier, Roger

    2007-01-01

    Kirjanduslikest tekstidest sotsiaalajaloo uurimisallikana, juhuse ja paratamatuse vahekorrast ajaloos ja Prantsuse revolutsiooni käsitlusest Pariisi õppe- ja teaduskeskuse Ecole des Hautes Etudes en Sciences Sociales professori R. Chartier'i teostes. Varem ilm.: Tekstid, praktikad ja lugejad : intervjuu Roger Chartier'ga // Chartier, Roger. Prantsuse revolutsiooni kultuurilised lätted. - Tallinn, 2002. - Lk. 274-290

  2. An Examination of Black Science Teacher Educators' Experiences with Multicultural Education, Equity, and Social Justice

    Science.gov (United States)

    Atwater, Mary M.; Butler, Malcolm B.; Freeman, Tonjua B.; Carlton Parsons, Eileen R.

    2013-01-01

    Diversity, multicultural education, equity, and social justice are dominant themes in cultural studies (Hall in "Cultural Dialogues in Cultural Studies." Routledge, New York, pp 261-274, 1996; Wallace 1994). Zeichner ("Studying Teacher Education: The Report of the AERA Panel on Research and Teacher Education." Lawrence Erlbaum…

  3. Kahe keelemehe regivärsiluulest / Ruth Mirov

    Index Scriptorium Estoniae

    Mirov, Ruth, 1928-

    1998-01-01

    Ilmunud ka kogumikus: Mirov, Ruth. Sõnast sõnasse : valik artikleid ja retsensioone. Tallinn ; Tartu : Eesti Keele Sihtasutus, 2002, lk. 261-274. Rahvaluulekogumikud: Aavik, Johannes. Valik rahvalaule. Tartu : Istandik, 1919; Saarbek, Albert [=Andrus Saareste]. Valitud eesti rahavalaulud koolidele. Tallinn : Rahvaülikool, 1919

  4. An Explicit-Inductive Approach to Grammar in Irish-Medium Immersion Schools

    Science.gov (United States)

    Ní Dhiorbháin, Aisling; Ó Duibhir, Pádraig

    2017-01-01

    This article focuses on qualitative self-report data from a mixed-methods study which investigated Grade 5 and 6 (n = 274), 11-12-year-old, Irish-medium (IM) immersion students' improvement in linguistic accuracy in response to an explicit-inductive approach to form-focused instruction (FFI). A series of typographically enhanced PowerPoint slides…

  5. Dicty_cDB: VSC263 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available . 278 1e-73 BT078708_1( BT078708 |pid:none) Lepeophtheirus salmonis Pacific fo... 274 2e-72 FJ376460_1( FJ376460 |pid:none) Spea hamm...ondii ribosomal protein L... 273 2e-72 ( P41116 ) RecName: Full=60S ribosomal prote

  6. Locomotive System

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    2008477 Diagnostic value of dystrophin in childhood and adolescent muscular disorders. ZHANG Meng(张萌), et al. Dept pathol, 1st Affili Hosp, Sun Yat-sen Univ, Guangzhou 510080.Chin J Nerv Ment Dis 2008;34(5):274-277. Objective To explore the diagnostic values of dystrophin immunohistochemical reaction in childhood and adolescent muscular disorders.

  7. heat storage in upper and lower body during high-intensity exercise ...

    African Journals Online (AJOL)

    Procedure: Seven SCI and 8 AB athletes (matched for arm- crank VO2 peak) ... Participants visited the laboratory on two separate occasions. On ... mal ACE stages and a rest stage had been completed, volunteers exercised to .... nificance was set at alpha≤0.05. A one-way ..... Phys Med Rehab 1976;57:268-274. 20.

  8. OMPHALOCELE AND GASTROSCHISIS IN EUROPE - A SURVEY OF 3-MILLION BIRTHS 1980-1990

    NARCIS (Netherlands)

    CALZOLARI, E; DOLK, H; MILAN, M; LECHAT, M; LEURQUIN, P; GOYENS, S; ASTOLFI, G; VOLPATO, S; AYME, S; CALABRO, A; CLEMENTI, M; TENCONI, R; CORNEL, M; CUSCHIERI, A; GARCIAMINAUR, S; GARNE, E; GILLEROT, Y; GOUJARD, J; HANSENKOENIG, D; ROULLEAUX, M; HOWARD, PJ; JOHNSON, Z; LILLIS, DF; NEVIN, NC; NELEN, [No Value; PEXIEDER, T; PIERINI, A; STOLL, C; STONE, DH

    1995-01-01

    A total of 732 cases of omphalocele and 274 cases of gastroschisis was registered in 21 regional registers in Europe (EUROCAT registers) during the period 1980-1990. The total prevalence rates were 2.52 pes 10,000 for omphalocele and 0.94 per 10,000 for gastroschisis. There was significant heterogen

  9. GEOCHRONOMETRY & ISOTOPE GEOLOGY

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    <正>20042213 Chen Qinghua (Department of Geology,Northwest University, Xi’an, Shaanxi); Liu Chiyang The Mathematical Representations and Their Significance of Geological Age with Milankovitch Theory (Journal of Northwest University (Natural Science Edition), ISSN1000 - 274X, CN61 -1072/N, 33(5), 2003, p. 599-602, 27 refs. )

  10. Revision of the Lauraceae III. The genera Aiouea, Systemonodaphne, Urbanodendron, Mezilaurus; additions and corrections to Licaria and Cryptocarya

    NARCIS (Netherlands)

    Kostermans, A.J.G.H.

    1938-01-01

    Aiouea Aublet, Hist. Guian. I (1775), p. 310; III, t. 120; Scopoli, Introductio Hist. nat. (Pragae 1777), p. 107, n. 277; Lamarck, Encyclop. méthod. I (1783), p. 72 (Ajúvea); Poiret, Encycl., Suppl. I (1890), p. 274, III (1893), p. 317; Illustrat. Genr. II, p. 395 et 367, t. 360; Jussieu, Genera (17

  11. Language Learning Strategies of Language e-Learners in Turkey

    Science.gov (United States)

    Solak, Ekrem; Cakir, Recep

    2015-01-01

    The purpose of this study was to determine the use of language learning strategies of e-learners and to understand whether there were any correlations between language learning strategies and academic achievement. Participants of the study were 274?e-learners, 132 males and 142 females, enrolled in an e-learning program from various majors and…

  12. Gclust Server: 201274 [Gclust Server

    Lifescience Database Archive (English)

    Full Text Available 201274 Sme_SMc04237 Cluster Sequences - 82 hypothetical protein 1 1.00e-40 0.0 0.0 0.0 0.0 3.23 0.0 Show 201...274 Cluster ID 201274 Sequence ID Sme_SMc04237 Link to cluster sequences Cluster Se

  13. Transcriptional Regulation of BRCA1

    Science.gov (United States)

    2000-08-01

    Ramos , L., Villasenor, M. R., Anders, K. H., Press, M. F., Clarke, K., Karlan, B., Chen, J. J., Scully, R., Livingston, D., Zuch, R. H., Kanter, M. H...Chem 274(44), 3 1297-304 22. Thakur, S., Lin, H. C., Tseng, W. T., Kumar, S., Bravo , R., Foss, F., Gelinas, C., and Rabson, A. B. (1994) Oncogene 9(8

  14. The Connor-Davidson Resilience Scale as a Positive Psychology Measure for People with Spinal Cord Injuries

    Science.gov (United States)

    Fujikawa, Mayu; Lee, Eun-Jeong; Chan, Fong; Catalano, Denise; Hunter, Celeste; Bengtson, Kevin; Rahimi, Maryam

    2013-01-01

    The main objective of this study is to evaluate the measurement structure of the Connor-Davidson Resilience Scale (CD-RISC) as a positive psychology measure for people with spinal cord injuries (SCIs) using confirmatory factor analysis. The participants consisted of 274 Canadians with SCI living in the community. The result indicated that the…

  15. Metric Selection for Ecosystem Restoration

    Science.gov (United States)

    2013-06-01

    Ecological conceptual models: A framework and case study on ecosystem management for South Florida sustainability. The Science of the Total Environment 274...assessment: Review of qualitative and quantitative approaches. Science of the Total Environment 407: 5199-5205. Linkov, I., and E. Moberg. 2011

  16. Burnout and Competency Development in Pre-Service Teacher Training

    Science.gov (United States)

    Rodríguez-Hidalgo, Antonio J.; Calmaestra, Juan; Dios, Irene

    2014-01-01

    Introduction: The burnout syndrome negatively affects the students' academic performance. The relation between academic burnout and the self-perception of skills in initial teacher training is subjected to analysis. Method: A sample of 274 students (average age = 20,61 years old) from the Bachelor Degree in Early Childhood Education and the…

  17. Data of evolutionary structure change: 1C8RA-3CODB [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 1C8RA-3CODB 1C8R 3COD A B TGRPEWIWLALGTALMGLGTLYFLVKGMGVSDPDAKKFY...ne>PHE CA 209 GLY CA 249 PHE CA 274 3COD... B 3CODB YILYVLFFGFTSKA...ne>GLU CA 222 VAL CA 302 3COD B 3CODB TSKAESMRPEV HHGGG

  18. Data of evolutionary structure change: 1C8RA-3CODA [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 1C8RA-3CODA 1C8R 3COD A A TGRPEWIWLALGTALMGLGTLYFLVKGMGVSDPDAKKFY...ne>PHE CA 209 GLY CA 249 PHE CA 274 3COD... A 3CODA YILYVLFFGFTSKA...>GLU CA 222 VAL CA 302 3COD A... 3CODA TSKAESMRPEV HHGGG H

  19. Exposure to slim images in mass media: Television commercials as reminders of restriction in restrained eaters [reprint

    NARCIS (Netherlands)

    Anschutz, D.J.; Strien, T. van; Engels, R.C.M.E.

    2011-01-01

    This reprinted article originally appeared in Health Psychology, 2008 (Jul), Vol 27(4), 401-408. (The following abstract of the original article appeared in record 2008-09239-001). Objective: The aim of the present study was to explore the effects of exposure to slim images and diet-related products

  20. High Energy Proton-Proton Elastic Scattering for Large Momentum Transfers and Van der Waals Type Model

    Science.gov (United States)

    Aleem, F.

    1980-03-01

    The most recent measurements of the angular distribution in proton-proton elastic scattering at sqrt{s}=27.4, 45 and 62GeV with squared four momentum transfer, -t, extending up to 14(GeV/c)2, have been explained using Van der Waals type model.

  1. Simple Regge pole model for proton-proton elastic scattering at high energies

    Energy Technology Data Exchange (ETDEWEB)

    Saleem, M.; Fazal-e-Aleem

    1979-06-01

    It is shown that by a phenomemological choice of residue functions, the angular distribution in pp elastic scattering at high energies, including the most recent measurement at ..sqrt..s = 27.4 GeV with squared 4-momentum transfer, -t, extending up to 14 (GeV/c)/sup 2/, can be explained with simple Regge pole model.

  2. Dispersion-managed semiconductor mode-locked ring laser.

    Science.gov (United States)

    Resan, Bojan; Archundia, Luis; Delfyett, Peter J; Alphonse, Gerard

    2003-08-01

    A novel breathing-mode external sigma-ring-cavity semiconductor mode-locked laser is developed. Intracavity pulse compression and stretching produce linearly chirped pulses with an asymmetric exponential temporal profile. External dispersion compensation reduces the pulse duration to 274 fs (within 10% of the bandwidth limit).

  3. Why Are Drugs So Hard to Quit?

    Medline Plus

    Full Text Available ... 41. TheNABCA 17,139 views 3:41 The Chemistry of Addiction - Duration: 11:50. SciShow 909,274 ... English Content location: United States Restricted Mode: Off History Help Loading... Loading... Loading... About Press Copyright Creators ...

  4. music performance as a therapy for managing stress amongst the ...

    African Journals Online (AJOL)

    USER

    The serious breakdown in health of the academics in Nigerian Federal Universities which placed them in ... Learning a musical instrument and playing music increases mathematical language, social skills and ... depression, improved mood and a reduction in state anxiety. The word ..... psychology 45 (3) 274 – 283. Music ...

  5. Interpersonal Problem Solving, Self-Compassion and Personality Traits in University Students

    Science.gov (United States)

    Arslan, Coskun

    2016-01-01

    The aim of this study was to investigate interpersonal problem solving in terms of self-compassion and personality traits. The participants were 570 (274 females and 296 males) who participated in the research voluntarily. The mean age of the participants was 21.54 years (between 17-32 years old) with a standard deviation of 2.68 years. Data were…

  6. 41 CFR 101-27.400 - Scope of subpart.

    Science.gov (United States)

    2010-07-01

    ... Regulations System FEDERAL PROPERTY MANAGEMENT REGULATIONS SUPPLY AND PROCUREMENT 27-INVENTORY MANAGEMENT 27.4-Elimination of Items From Inventory § 101-27.400 Scope of subpart. This subpart establishes policy and... sources, Government or commercial, are eliminated from inventory. For items which are not readily...

  7. CELEBRATING OUR SUBJECTIVITY: Research as Lived Experience

    African Journals Online (AJOL)

    being involved in a community-initiated ... people who live and work in this industrial ... McCormack Park was reclaimed over thirty years ago to serve as a storm water overflow and a ... $274 million more on education than was necessary.

  8. Data of evolutionary structure change: 1A4VA-1JKBA [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 1A4VA-1JKBA 1A4V 1JKB A A KQFTKCELSQLLKDI--DGYGGIALPELICTMFHTSGYD...line> 1JKB A 1JK...CA 299 GLU CA 390 1JKB A 1JK...line> ASP CA 274 TYR CA 329 1JKB ...A 1JKBA RVVRDPQGIRA

  9. A catalogue of the Coelenterate type specimens of the Zoological Museum of Amsterdam. IV. Gorgonacea, Actiniaria, Scleractinia

    NARCIS (Netherlands)

    Soest, van R.W.M.

    1979-01-01

    This final part of the Coelenterate type catalogue lists 274 nominal types (183 Gorgonacea, 9 Actiniaria and 82 Scleractinia). Six not previously depicted types are represented by photographic illustrations of their habit. Furthermore lists are provided of schizotypes, i.e. fragments of types housed

  10. Data of evolutionary structure change: 1B1ZA-2NTSA [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 1B1ZA-2NTSA 1B1Z 2NTS A A DPDPSQLHRSSLVKNLQNIYFLYE-GDPVTHENVKSVDQ...ELDYKVRKYLTDNKQLYTN--------------GPSKYETGYIKFIPKNKESFWFDFF-PEPEFTQSKYLMIYKDNETLDSNTSQIEVYLTT-- ...ine> 2NTS A 2NTSA 2NTS A 2NTS.../line> PHE CA 274 2NTS A 2NTS

  11. 40 CFR Appendix A to Part 97 - Final Section 126 Rule: EGU Allocations, 2004-2007

    Science.gov (United States)

    2010-07-01

    ... 7 337 OH R E BURGER 2864 8 274 OH RICHARD GORSUCH 7286 1 146 OH RICHARD GORSUCH 7286 2 138 OH RICHARD GORSUCH 7286 3 144 OH RICHARD GORSUCH 7286 4 146 OH W H SAMMIS 2866 1 402 OH W H SAMMIS 2866 2...

  12. DMPD: The oxidation of lipoproteins by monocytes-macrophages. Biochemical andbiological mechanisms. [Dynamic Macrophage Pathway CSML Database

    Lifescience Database Archive (English)

    Full Text Available logical mechanisms. Chisolm GM 3rd, Hazen SL, Fox PL, Cathcart MK. J Biol Chem. 1999 Sep 10;274(37):25959-62...onocytes-macrophages. Biochemical andbiological mechanisms. Authors Chisolm GM 3rd, Hazen SL, Fox PL, Cathcart

  13. An Analysis of the Relationship between Organizational Communication and Organizational Cynicism According to Teachers' Perceptions in Turkey

    Science.gov (United States)

    Ayik, Ahmet

    2015-01-01

    In this study, the relations between organizational communication and organizational cynicism have been analyzed. The sample of the study consists of 274 teachers working in state secondary schools in Palandöken County of Erzurum, in 2013-2014 academic year. "Organizational Cynicism Scale" and "Organizational Communication…

  14. Modeling the Carbon Implications of Ecologically Based Forest Management

    Science.gov (United States)

    2015-08-20

    Journal of Forestry 111, 59-66. Samuelson , L.J., Stokes, T.A., Johnsen, K.H., 2012. Ecophysiological comparison of 50-year-old longleaf pine, slash pine...and loblolly pine. Forest Ecology and Management 274, 108-115. Samuelson , L.J., Whitaker, W.B., 2012. Relationships between Soil CO2 Efflux and

  15. Modeling the Carbon Implications of Ecologically-Based Forest Management

    Science.gov (United States)

    2015-08-01

    Journal of Forestry 111, 59-66. Samuelson , L.J., Stokes, T.A., Johnsen, K.H., 2012. Ecophysiological comparison of 50-year-old longleaf pine, slash pine...and loblolly pine. Forest Ecology and Management 274, 108-115. Samuelson , L.J., Whitaker, W.B., 2012. Relationships between Soil CO2 Efflux and

  16. Homology to peptide pattern for annotation of carbohydrate-active enzymes and prediction of function

    DEFF Research Database (Denmark)

    Busk, Peter Kamp; Pilgaard, Bo; Lezyk, Mateusz Jakub

    2017-01-01

    Background: Carbohydrate-active enzymes are found in all organisms and participate in key biological processes.These enzymes are classified in 274 families in the CAZy database but the sequence diversity within each family makes it a major task to identify new family members and to provide basis ...

  17. ELT Research in Turkey: A Content Analysis of Selected Features of Published Articles

    Science.gov (United States)

    Yagiz, Oktay; Aydin, Burcu; Akdemir, Ahmet Selçuk

    2016-01-01

    This study reviews a selected sample of 274 research articles on ELT, published between 2005 and 2015 in Turkish contexts. In the study, 15 journals in ULAKBIM database and articles from national and international journals accessed according to convenience sampling method were surveyed and relevant articles were obtained. A content analysis was…

  18. Gclust Server: 17217 [Gclust Server

    Lifescience Database Archive (English)

    Full Text Available 17217 Bja_bll4927 Cluster Sequences Related Sequences(26) 274 hypothetical protein ...6 1.00e-19 0.0 0.0 4.0 0.0 9.68 0.0 Show 17217 Cluster ID 17217 Sequence ID Bja_bll4927 Link to cluster sequ

  19. Dicty_cDB: Contig-U14809-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available ) Plasmodium falciparum adhesive-like protein pseud... 40 0.10 2 ( CU302368 ) Pig...4B16 in... 36 0.10 4 ( AC079638 ) Genomic sequence for Mus musculus, clone RP23-274... 40 0.10 2 ( AF324831

  20. Similarity in General Mental Ability in Bedouin Full and Half Siblings.

    Science.gov (United States)

    Elbedour, Salman; Hur, Yoon-Mi; Bouchard, Thomas J., Jr.

    1997-01-01

    A battery of "g" loaded mental ability tests was administered to 274 Bedouin children and adolescents, full and half siblings from 106 families. Results demonstrate internal validity for the tests in this cultural context and support the idea that shared family environment is a strong determinant of sibling similarity for children in the given age…

  1. 75 FR 42575 - Electronic Signature and Storage of Form I-9, Employment Eligibility Verification

    Science.gov (United States)

    2010-07-22

    ... SECURITY 8 CFR Part 274a RIN 1653-AA47 Electronic Signature and Storage of Form I-9, Employment Eligibility.... Regulatory History In June 2006, DHS published an interim final rule to permit electronic signature and... because electronic signature and storage technologies are optional, DHS expects that small entities...

  2. Influenza virus resistance to oseltamivir: what are the implications?

    NARCIS (Netherlands)

    Fleming, D.M.; Elliot, A.J.; Meijer, A.; Paget, W.J.

    2009-01-01

    Influenza caused by an oseltamivir-resistant influenza A(H1N1) virus was widespread across Europe during the 2007–08 winter. About 25% of A(H1N1) viruses tested in the European Influenza Surveillance Scheme (EISS) were resistant with an H274Y mutation in the neuraminidase glycoprotein. Early

  3. 40 CFR 266.210 - What definitions apply to this subpart?

    Science.gov (United States)

    2010-07-01

    ... under subsection 274b of the Atomic Energy Act of 1954, as amended (68 Stat. 919), to assume... sufficient to form a critical mass. Certified delivery means certified mail with return receipt requested, or... regulated by NRC, or NRC Agreement States, under authority of the Atomic Energy Act of 1954, as amended....

  4. 75 FR 16163 - Announcement of Funding Awards for the HUD-Veterans Affairs Supportive Housing (HUD-VASH) Program...

    Science.gov (United States)

    2010-03-31

    ... ] Street, SW., Room 4228, Washington, DC 20410, telephone number (202) 402-5264. For the hearing or speech... Service at 1 (800) 877-8339. (Other than the ``800'' TTY number, these telephone numbers are not toll-free... County Housing Authority..... 1855 Constitution Avenue. Woodlyn PA 19094 274,485 35 Hous Authority of...

  5. Associations between somatic cell count patterns and the incidence of clinical mastitis

    NARCIS (Netherlands)

    Haas, de Y.; Barkema, H.W.; Schukken, Y.H.; Veerkamp, R.F.

    2005-01-01

    Associations between clinical mastitis (CM) and the proportional distribution of patterns in somatic cell count (SCC) on a herd level were determined in this study. Data on CM and SCC over a 12-month period from 274 Dutch herds were used. The dataset contained parts of 29,719 lactations from 22,955

  6. Histone Code Modulation by Oncogenic PWWP-Domain Protein in Breast Cancers

    Science.gov (United States)

    2014-08-01

    breast and colorectal cancers. Science 314: 268–274. Solomon DA, Kim JS, Cronin JC, Sibenaller Z, Ryken T, Rosenberg SA et al. (2008). Mutational...Beroukhim R, Mermel CH, Loda M, Ait-Si- Ali S, Garraway LA, Young RA and Zon LI. The histone methyltrans- ferase SETDB1 is recurrently amplified in mela

  7. 78 FR 70368 - Self-Regulatory Organizations; Chicago Mercantile Exchange Inc.; Notice of Filing and Immediate...

    Science.gov (United States)

    2013-11-25

    ....A. Regarding Timing of Determination of the Spot Exchange Rate of Chilean Peso per United States....02.A. regarding cash settlement of Cleared OTC USD/CLP Spot, Forwards and Swaps Contracts. II. Self... error in the current rule text of CME Rule 274H.02.A. regarding Cash Settlement of Cleared OTC...

  8. EST Table: FS830202 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available FS830202 E_FL_fmgV_34C08_R_0 10/09/28 94 %/274 aa ref|NP_001040163.1| ischemia/repe...rfusion inducible protein [Bombyx mori] gb|ABD36179.1| ischemia/reperfusion inducible protein [Bombyx mori

  9. 17 CFR 240.10b-18 - Purchases of certain equity securities by the issuer and others.

    Science.gov (United States)

    2010-04-01

    ... report their repurchasing activity as required by Item 8 of Form N-CSR (17 CFR 249.331; 17 CFR 274.128). (a) Definitions. Unless otherwise provided, all terms used in this section shall have the same meaning as in the Act. In addition, the following definitions shall apply: (1) ADTV means the...

  10. Data of evolutionary structure change: 1DFIA-3FNFD [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available EVID>EVID> 3 3FNF D 3FNF...1DFIA-3FNFD 1DFI 3FNF A D -GFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTY...HHHHHHHHHHHHHHHHHHHHH EEEEEE HHHHHHHHHHHH HHHHHHHHHHH EEEEE GGG -- ...EVID>EVID> 0 1DFI A...e>ASP CA 274 ILE CA 353 VAL CA 389 3FNF

  11. College Students' Social Justice Interest and Commitment: A Social-Cognitive Perspective

    Science.gov (United States)

    Miller, Matthew J.; Sendrowitz, Kerrin; Connacher, Christopher; Blanco, Susana; de La Pena, Cristina Muniz; Bernardi, Shaina; Morere, Lauren

    2009-01-01

    In this study, the authors examined the degree to which social-cognitive career theory (SCCT; R. W. Lent, S. D. Brown, & G. Hackett, 1994) explained the development of social justice interest and commitment. Data from 274 college students and latent variable path modeling were used to test theoretically and empirically derived SCCT direct and…

  12. 77 FR 751 - Federal Motor Vehicle Safety Standards; Matters Incorporated by Reference

    Science.gov (United States)

    2012-01-06

    ... Pavements Using a Two-Wheel Trailer,'' issued 1965, into Sec. 571.208. (29) ASTM E274-70, ``Standard Method...) SAE Recommended Practice J972, ``Moving Rigid Barrier Collision Tests,'' revised May 2000, into Sec... systems. * * * * * S4 * * * Skid number means the frictional resistance of a pavement measured in...

  13. 78 FR 21850 - Federal Motor Vehicle Safety Standards; Matters Incorporated by Reference

    Science.gov (United States)

    2013-04-12

    ... Resistance of Pavements Using a Two-Wheel Trailer.'' The Alliance asserts that ASTM E274-65T was a... Pavements Using a Two-Wheel Trailer,'' issued 1965, into Sec. Sec. 571.208; 571.301. * * * * * 0 3. Amend... tested is level, rigid, and of uniform construction, with a skid number of 75 when measured in accordance...

  14. Experiment list: SRX573067 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available lonal (Bethyl, A301-274A) || source=IP with Ab anti-INTS11 rabbit polyclonal...=HeLa || cell line=HeLa || treatment=INTS11 occupancy examined cycling non starved wt Hela Cells || antibody=anti-INTS11 rabbit polyc

  15. Experiment list: SRX573068 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available lonal (Bethyl, A301-274A) || source=IP with Ab anti-INTS11 rabbit polyclonal...=HeLa || cell line=HeLa || treatment=INTS11 occupancy examined cycling non starved wt Hela Cells || antibody=anti-INTS11 rabbit polyc

  16. CpG-ODN attenuates pathological cardiac hypertrophy and heart failure by activation of PI3Kα-Akt signaling.

    Directory of Open Access Journals (Sweden)

    Liang Yang

    Full Text Available Phosphoinositide-3-kinase α (PI3Kα represents a potential novel drug target for pathological cardiac hypertrophy (PCH and heart failure. Oligodeoxynucleotides containing CpG motifs (CpG-ODN are classic agonists of Toll-like receptor 9 (TLR9, which typically activates PI3K-Akt signaling in immune cells; however, the role of the nucleotide TLR9 agonists in cardiac myocytes is largely unknown. Here we report that CpG-ODN C274 could both attenuate PCH and improve cardiac dysfunction by activating PI3Kα-Akt signaling cascade. In vitro studies indicated that C274 could blunt reactivation of fetal cardiac genes and cell enlargement induced by a hypertrophic agent, isoproterenol. The anti-hypertrophic effect of C274 was suppressed by a pan-PI3K inhibitor, LY294002, or a small interfering RNA targeting PI3Kα. In vivo studies demonstrated that PCH, as marked by increased heart weight (HW and cardiac ANF mRNA, was normalized by pre-administration with C274. In addition, Doppler echocardiography detected cardiac ventricular dilation, and contractile dysfunction in isoproterenol-treated animals, consistent with massive replacement fibrosis, reflecting cardiac cell death. As expected, pre-treatment of mice with C274 could prevent cardiac dysfunction associated with diminished cardiac cell death and fibrosis. In conclusion, CpG-ODNs are novel cardioprotective agents possessing antihypertrophic and anti-cell death activity afforded by engagement of the PI3Kα-Akt signaling. CpG-ODNs may have clinical use curbing the progression of PCH and preventing heart failure.

  17. Odd-Z Transactinide Compound Nucleus Reactions Including the Discovery of 260Bh

    Energy Technology Data Exchange (ETDEWEB)

    Nelson, Sarah L. [Univ. of California, Berkeley, CA (United States)

    2008-01-01

    Several reactions producing odd-Z transactinide compound nuclei were studiedwith the 88-Inch Cyclotron and the Berkeley Gas-Filled Separator at the Lawrence Berkeley National Laboratory. The goal was to produce the same compound nucleus ator near the same excitation energy with similar values of angular momentum via differentnuclear reactions. In doing so, it can be determined if there is a preference in entrancechannel, because under these experimental conditions the survival portion of Swiatecki, Siwek-Wilcznska, and Wilczynski's"Fusion By Diffusion" model is nearly identical forthe two reactions. Additionally, because the same compound nucleus is produced, theexit channel is the same. Four compound nuclei were examined in this study: 258Db, 262Bh, 266Mt, and 272Rg. These nuclei were produced by using very similar heavy-ion induced-fusion reactions which differ only by one proton in the projectile or target nucleus (e.g.: 50Ti + 209Bi vs. 51V + 208Pb). Peak 1n exit channel cross sections were determined for each reaction in each pair, and three of the four pairs' cross sections were identical within statistical uncertainties. This indicates there is not an obvious preference of entrancechannel in these paired reactions. Charge equilibration immediately prior to fusionleading to a decreased fusion barrier is the likely cause of this phenomenon. In addition to this systematic study, the lightest isotope of element 107, bohrium, was discovered in the 209Bi(52Cr,n) reaction. 260Bh was found to decay by emission of a 10.16 MeV alpha particle with a half-life of 35$+19\\atop{-9}$ ms. The cross section is 59 pb at an excitation energy of 15.0 MeV. The effect of the N = 152 shell is also seen in this isotope's alpha particle energy, the first evidence of such an effect in Bh. All reactions studied are also compared to model predictions by Swiatecki

  18. Planck intermediate results XXXI. Microwave survey of Galactic supernova remnants

    DEFF Research Database (Denmark)

    Arnaud, M.; Ashdown, M.; Atrio-Barandela, F.

    2016-01-01

    The all-sky Planck survey in 9 frequency bands was used to search for emission from all 274 known Galactic supernova remnants. Of these, 16 were detected in at least two Planck frequencies. The radio-through-microwave spectral energy distributions were compiled to determine the mechanism for micr......The all-sky Planck survey in 9 frequency bands was used to search for emission from all 274 known Galactic supernova remnants. Of these, 16 were detected in at least two Planck frequencies. The radio-through-microwave spectral energy distributions were compiled to determine the mechanism...... for microwave emission. In only one case, IC 443, is there high-frequency emission clearly from dust associated with the supernova remnant. In all cases, the low-frequency emission is from synchrotron radiation. As predicted for a population of relativistic particles with energy distribution that extends...

  19. Chalcones as novel influenza A (H1N1) neuraminidase inhibitors from Glycyrrhiza inflata

    DEFF Research Database (Denmark)

    Dao, Trong Tuan; Nguyen, Phi Hung; Lee, Hong Sik

    2011-01-01

    The emergence of highly pathogenic influenza A virus strains, such as the new H1N1 swine influenza (novel influenza), represents a serious threat to global human health. During our course of an anti-influenza screening program on natural products, one new licochalcone G (1) and seven known (2......-8) chalcones were isolated as active principles from the acetone extract of Glycyrrhiza inflata. Compounds 3 and 6 without prenyl group showed strong inhibitory effects on various neuraminidases from influenza viral strains, H1N1, H9N2, novel H1N1 (WT), and oseltamivir-resistant novel H1N1 (H274Y) expressed...... in 293T cells. In addition, the efficacy of oseltamivir with the presence of compound 3 (5 μM) was increased against H274Y neuraminidase. This evidence of synergistic effect makes this inhibitor to have a potential possibility for control of pandemic infection by oseltamivir-resistant influenza virus....

  20. Magnetic properties of crystalline and amorphous Fe-B alloys prepared by electroless plating

    Energy Technology Data Exchange (ETDEWEB)

    Zhang Bangwei (CCAST (World Lab.), Beijing (China) Dept. of Physics, Hunan Univ., Changsha (China)); Hu Wangyu; Zhu Deqi (Dept. of Physics, Hunan Univ., Changsha (China))

    1993-01-01

    Amorphous samples of Fe[sub 100-x]B[sub x] (x=18, 24, 27.4) and crystalline samples of Fe[sub 100-x]B[sub x] (x=2.2, 10.6) have been prepared by electroless plating. Their magnetic properties have been studied. The Curie temperature Tc increases upon increasing the boron concentration for the amorphous alloys from 613 K (x=18) to 776 K (x=27.4). However, the saturation magnetization and magnetic moment decrease with increasing boron concentration for both the crystalline and amorphous alloys. The data have been analyzed and discussed using the molecular-field theory and the rigid-band theory and the charge transfer of sp electrons from the metalloids to the d-band of the transition metals. The dependence of the magnetic properties of the amorphous alloys on heat treatment has also been studied. (orig.).

  1. FAST TRACK COMMUNICATION: Quantum chaos on discrete graphs

    Science.gov (United States)

    Smilansky, Uzy

    2007-07-01

    Adapting a method developed for the study of quantum chaos on quantum (metric) graphs (Kottos and Smilansky 1997 Phys. Rev. Lett. 79 4794, Kottos and Smilansky 1999 Ann. Phys., NY 274 76), spectral ζ functions and trace formulae for discrete Laplacians on graphs are derived. This is achieved by expressing the spectral secular equation in terms of the periodic orbits of the graph and obtaining functions which belong to the class of ζ functions proposed originally by Ihara (1966 J. Mat. Soc. Japan 18 219) and expanded by subsequent authors (Stark and Terras 1996 Adv. Math. 121 124, Kotani and Sunada 2000 J. Math. Sci. Univ. Tokyo 7 7). Finally, a model of 'classical dynamics' on the discrete graph is proposed. It is analogous to the corresponding classical dynamics derived for quantum graphs (Kottos and Smilansky 1997 Phys. Rev. Lett. 79 4794, Kottos and Smilansky 1999 Ann. Phys., NY 274 76).

  2. Results from PLUTO at PETRA

    CERN Document Server

    Blobel, Volker

    1979-01-01

    Results obtained at the e/sup +/e/sup -/ storage ring PETRA by the PLUTO collaboration at c.m. energies of 13, 17 and 27.4 GeV are presented. New limits on QED cut-off parameters are determined from Bhabha scattering; at 27.4 GeV the limits are Lambda /sub +/>38 GeV and Lambda /sub -/>60 GeV. The measured values of the total hadronic cross section, and the study of the jet character of the hadronic events are well consistent with the expected production of b mesons (with q/sub b/=1/3), but do not require additional new quarks with charge 2/3. Hadronic events from two-photon exchange processes are observed with comparable rates as events from one-photon exchange. First results on the hadronic cross section in gamma gamma collisions are given. (8 refs).

  3. Suppression of Instability in Rotatory Hydromagnetic Convection

    Indian Academy of Sciences (India)

    Joginder S Dhiman

    2000-08-01

    Recently discovered hydrodynamic instability [1], in a simple Bénard configuration in the parameter regime 02 > 1 under the action of a nonadverse temperature gradient, is shown to be suppressed by the simultaneous action of a uniform rotation and a uniform magnetic field both acting parallel to gravity for oscillatory perturbations whenever $(\\mathscr{Q}_1/^2+\\mathscr{J}/^4) > 1$ and the effective Rayleigh number $\\mathcal{R}$(1-02) is dominated by either 274(1 + 1/1)/4 or 274/2 according as 1 ≥ 1 or 1 ≤ 1 respectively. Here 0 is the temperature of the lower boundary while 2 is the coefficient of specific heat at constant volume due to temperature variation and 1, $\\mathcal{R}, \\mathscr{Q}$ and $\\mathscr{T}$ respectively denote the magnetic Prandtl number, the Rayleigh number, the Chandrasekhar number and the Taylor number.

  4. Development of renewable energy 2014/15. Wind power keeps the energy turnaround on course; Entwicklung der erneuerbaren Energien 2014/15. Windkraft haelt die Energiewende auf Kurs

    Energy Technology Data Exchange (ETDEWEB)

    Musiol, Frank; Bickel, Peter; Nieder, Thomas [Zentrum fuer Sonnenenergie- und Wasserstoff-Forschung Baden-Wuerttemberg (ZSW), Stuttgart (Germany)

    2015-10-15

    An expansion of wind energy use in barely thought possible extent has contributed significantly to the fact that electricity production achieving a significant increase of renewable energy in 2014 and their share in gross electricity consumption could rise to 27.4% in Germany. So the wind ensured that the energy transition could be kept on course, as in the renewable energy in the heating and transport sectors did like in previous years, little. [German] Ein Ausbau der Windenergienutzung in kaum fuer moeglich gehaltenem Ausmass hat wesentlich dazu beigetragen, dass die Stromerzeugung aus erneuerbaren Energien auch im Jahr 2014 ein deutliches Plus erzielen und ihr Anteil am Bruttostromverbrauch in Deutschland auf 27.4 % steigen konnte. So sorgte die Windkraft dafuer, dass die Energiewende weiter auf Kurs gehalten werden konnte, denn bei den Erneuerbaren im Waerme- und Verkehrssektor tat sich wie schon in den Vorjahren wenig.

  5. A method to measure the effect of food appearance factors on children´s visual preferences

    DEFF Research Database (Denmark)

    Kildegaard, Heidi; Olsen, A.; Gabrielsen, G.

    2011-01-01

    The aim of the study was to examine children’s visual preferences for two food products; yoghurts and smoothies, by using a conjoint layout. In total, 274 children performed an incomplete ranking of 8 pictures formed by three factors each with two levels (23 design). The three food appearance fac...... between food appearance factors and segmentation factors were found. Additionally gender and ethnicity were found to be influential drivers for food choice.......The aim of the study was to examine children’s visual preferences for two food products; yoghurts and smoothies, by using a conjoint layout. In total, 274 children performed an incomplete ranking of 8 pictures formed by three factors each with two levels (23 design). The three food appearance...

  6. Continuous brightening of IGR J17473-2721

    DEFF Research Database (Denmark)

    Baldovin Saavedra, C.; Chenevez, Jérôme; Kuulkers, E.

    2008-01-01

    Renewed accretion activity has been reported by Swift/XRT (ATel #1459), XTE/PCA (ATel #1460) and INTEGRAL/IBIS/ISGRI (ATel #1461) from the RXTE transient IGR J17473-2721 (= XTE J1747-274; ATels #467, #498) after the detection of an X-ray burst by SuperAGILE (ATel #1445). From the on-going Galacti...... bulge monitoring program (see ATels #1385, #1461) we report that the transient continues to brighten as seen with IBIS/ISGRI and JEM-X.......Renewed accretion activity has been reported by Swift/XRT (ATel #1459), XTE/PCA (ATel #1460) and INTEGRAL/IBIS/ISGRI (ATel #1461) from the RXTE transient IGR J17473-2721 (= XTE J1747-274; ATels #467, #498) after the detection of an X-ray burst by SuperAGILE (ATel #1445). From the on-going Galactic...

  7. Dynamics and Mechanism of Efficient DNA Repair Reviewed by Active-Site Mutants

    Science.gov (United States)

    Tan, Chuang; Liu, Zheyun; Li, Jiang; Guo, Xunmin; Wang, Lijuan; Zhong, Dongping

    2010-06-01

    Photolyases repair the UV-induced pyrimidine dimers in damage DNA via a photoreaction which includes a series of light-driven electron transfers between the two-electron-reduced flavin cofactor FADH^- and the dimer. We report here our systematic studies of the repair dynamics in E. coli photolyase with mutation of several active-site residues. With femtosecond resolution, we observed the significant change in the forward electron transfer from the excited FADH^- to the dimer and the back electron transfer from the repaired thymines by mutation of E274A, R226A, R342A, N378S and N378C. We also found that the mutation of E274A accelerates the bond-breaking of the thymine dimer. The dynamics changes are consistent with the quantum yield study of these mutants. These results suggest that the active-site residues play a significant role, structurally and chemically, in the DNA repair photocycle.

  8. Developments for transactinide chemistry experiments behind the gas-filled separator TASCA

    Energy Technology Data Exchange (ETDEWEB)

    Even, Julia

    2011-12-13

    synthesised carbonyl complexes were identified by nuclear decay spectroscopy. Some complexes were studied with isothermal chromatography or thermochromatography methods. The chromatograms were compared with Monte Carlo Simulations to determine the adsorption enthalpyrnon silicon dioxide and on gold. These simulations based on existing codes, that were modified for the different geometries of the chromatography channels. All observed adsorption enthalpies (on silcon oxide as well as on gold) are typical for physisorption. Additionally, the thermalstability of some of the carbonyl complexes was studied. This showed that at temperatures above 200 C therncomplexes start to decompose. It was demonstrated that carbonyl-complex chemistry is a suitable method to study rutherfordium, dubnium, seaborgium, bohrium, hassium, and meitnerium. Until now, only very simple, thermally stable compounds have been synthesized in the gas-phase chemistry of the transactindes. With the synthesis of transactinide-carbonyl complexes a new compound class would be discovered. Transactinide chemistry would reach the border between inorganic and metallorganic chemistry. Furthermore, the in-situ synthesised carbonyl complexes would allow nuclear spectroscopy studies under low background conditions making use of chemically prepared samples. [German] Die vorliegende Arbeit befasst sich mit der Entwicklung von Experimenten hinter dem gasgefuellten Separator TASCA (TransActinide Separator and Chemistry Apparatus) zur Studie des chemischen Verhaltens der Transactinide. Zum einen wurde die Moeglichkeit der elektrochemischen Abscheidung kurzlebiger Isotope der Elemente Ruthenium und Osmium auf Goldelektroden im Hinblick auf ein Experiment mit Hassium untersucht. Aus der Literatur ist bekannt, dass bei der elektrochemischen Abscheidung einzelner Atome das Abscheidepotential signifikant vom Nernst-Potential abweicht. Die Verschiebung des Potentials haengt von der Adsorptionsenthalpie des abzuscheidenden Elements

  9. Sealing of Corneal Lacerations Using Photo-Activated Rose Bengal Dye and Amniotic Membrane

    Science.gov (United States)

    2017-01-10

    anesthesia, then 106 prepped and draped in the normal sterile fashion for eye surgery. A lid speculum was placed in 107 the eye and centered under the...analysis was performed using a five point grading system (0-4) for each of the 147 above variables. A score of zero was assigned for no observable...healing of 274 the surface after scraping and neovascularization. None of the animals scored over one on the 275 zero to four scale. The

  10. Domain Modeling: NP_689624.1 [SAHG[Archive

    Lifescience Database Archive (English)

    Full Text Available NP_689624.1 chr7 Classic zinc finger, C2H2 d2csha1 chr7/NP_689624.1/NP_689624.1_hol...o_214-262.pdb psi-blast 270N,272D,273G,274E,286H,287R,290Q,298C,300P,301C,302G,303K,314R,318H _ZN 0 ...

  11. Organizational and Systems Theory: An Integrated Review

    Science.gov (United States)

    1980-09-30

    because it was this type with which Darwin was concerned in his studies of biological species as systems. Numerous authors--including Ashby (1960), Marney...bases of social power. In D. Cartwright (Ed.), Studies in social ower. Ann Arbor: University of Michigan Institut for Social Research, 1959...N •274 2* 4" * *.* * .*I Guetzkow, H. E. Differentittion of roles in task-oriented tasks. In D. Cartwright , a’ A. Zander (jEds.), GrouT dynamics

  12. Book Reviews

    Directory of Open Access Journals (Sweden)

    Abdul Rahman Bin Yusop

    1964-07-01

    Full Text Available - J.J. Ras, A. Antonissen, Kadazan-English and English-Kadazan dictionary. Government Printing Office, Canberra, 1958; 274 p. - J. Noorduyn, Edith Bront Checchi, Grammatica della Lingua Indonesiana. Roma 1962. 127 pp. - R. Jones, Abdul Rahman Bin Yusop, Collins Malay Gem Dictionary, Malay-English: English-Malay. Collins, Edinburgh 1964. - G.W.J. Drewes, Alessandro Bausani, Malesia, Poesie e leggende, a cura di Alessandro Bausani. Nuova Accademia Editrice, Milano 1963. XLIV, 321 pp., 16 platen.

  13. Urinary albumin in space missions

    DEFF Research Database (Denmark)

    Cirillo, Massimo; De Santo, Natale G; Heer, Martina

    2002-01-01

    Proteinuria was hypothesized for space mission but research data are missing. Urinary albumin, as index of proteinuria, was analyzed in frozen urine samples collected by astronauts during space missions onboard MIR station and on ground (control). Urinary albumin was measured by a double antibody...... radioimmunoassay. On average, 24h urinary albumin was 27.4% lower in space than on ground; the difference was statistically significant. Low urinary albumin excretion could be another effect of exposure to weightlessness (microgravity)....

  14. HISTORICAL GEOLOGY & STRATIGRAPHY

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    <正>20082513 Chen Guocheng(State Key Labo- ratory of Marine Geology,Tongji University, Shanghai 200092,China);Zheng Hongbo Sedimentary Records of Volcanic Activities in the South China Sea over the Past 480 ka (Marine Geology & Quaternary Geology, ISSN0256—1492,CN37—1117/P,27(4), 2007,p.69—76,4 illus.,1 table,25 refs., with English abstract) Key words:sedimentary sequence,South China Sea

  15. Caffeine, Adenosine Receptors and Estrogen in Toxin Models of Parkinson’s Disease

    Science.gov (United States)

    2009-10-01

    inversely related to clinical progression of PD. The internal consistency of the results across the primary and secondary end points sup- ports their...for myocardial infarction and stroke: the Rotterdam study. Stroke. 2006; 37(6):1503-1507. 52. Wheeler JG, Juzwishin KD, Eiriksdottir G, Gudnason V...behavior in the rat: have we wasted our time? Exp Neurol 197:269-274. MorelliM, Di Paolo T, Wardas J, Calon F, Xiao D, Schwarzschild MA (2007) Role of

  16. Effects of strength training program on hip extensors and knee extensors strength of lower limb in children with spastic diplegic cerebral palsy

    OpenAIRE

    Aye, Thanda; Thein, Soe; Hlaing, Thaingi

    2016-01-01

    [Purpose] The purpose of this study was to determine whether strength training programs for hip extensors and knee extensors improve gross motor function of children with cerebral palsy in Myanmar. [Subjects and Methods] Forty children (25 boys and 15 girls, mean age: 6.07 ± 2.74 years) from National Rehabilitation Hospital, Yangon, Myanmar, who had been diagnosed with spastic diplegic cerebral palsy, Gross Motor Classification System I and II participated in a 6-week strength training progra...

  17. 17 CFR 270.30a-2 - Certification of Form N-CSR and Form N-Q.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Certification of Form N-CSR... Form N-CSR and Form N-Q. (a) Each report filed on Form N-CSR (§§ 249.331 and 274.128 of this chapter... must include certifications in the form specified in Item 12(a)(2) of Form N-CSR or Item 3 of Form...

  18. Domain Modeling: NP_001034464.1 [SAHG[Archive

    Lifescience Database Archive (English)

    Full Text Available NP_001034464.1 chr20 Crystal structure of putative methyltransferase (YP_321342.1) ...from Anabaena variabilis ATCC 29413 at 1.90 A resolution p3ccfa_ chr20/NP_001034464.1/NP_001034464.1_holo_71-283.pdb psi-blast 131L,134H,135W,160M,161F,166L,189S,191F,273Y,274Q BEZ 0 ...

  19. Dicty_cDB: Contig-U14008-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available 95,242,211,685 Length adjustment: 22 Effective length of query: 88 Effective length of database: 93,199,600,587 Effective... search space: 8201564851656 Effective search space used: 8201564851656 X1: 11 (21.8 bits) S2:...ase: 1,051,180,864 Length adjustment: 10 Effective length of query: 26 Effective ...length of database: 1,018,815,274 Effective search space: 26489197124 Effective search space used: 264891971

  20. Dicty_cDB: Contig-U13122-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available : 95,242,211,685 Length adjustment: 22 Effective length of query: 88 Effective le...ngth of database: 93,199,600,587 Effective search space: 8201564851656 Effective search space used: 82015648...051,180,864 Length adjustment: 10 Effective length of query: 26 Effective length of database: 1,018,815,274 Effective... search space: 26489197124 Effective search space used: 26489197124 Neig

  1. Ultraviolet light emitting diodes by ammonia molecular beam epitaxy on metamorphic (KAUST Repository

    Young, Erin C.

    2015-09-01

    © 2015. In this paper we demonstrate ultraviolet (UV) light emitting diodes (LEDs) grown on metamorphic AlGaN buffers on freestanding GaN (202-1) substrates by ammonia assisted molecular beam epitaxy (MBE). Misfit and related threading dislocations were confined to the stress relaxed, compositionally graded buffer layers, and single quantum well devices emitting at 355, 310 and 274. nm were grown on top of the graded buffers. The devices showed excellent structural and electrical (I-. V) characteristics.

  2. The Intrusion of Engine Exhaust into the Passenger Areas of Recreational Power Boats

    Science.gov (United States)

    1991-07-01

    Annapolis, Maryland. The test boat was a 34-foot Silverton sedan cruiser equipped with twin 302 CID engines with exhaust exits located on each side of the...40.60 30.14 1.42 09:36:31 51.80 41.90 30.14 2.74 -001 -000 -@00 @00 test oeat: 361 Silverton Sedan Cruiser 19:27:01 51.30 42.70 30.14 1.53 *forever

  3. Ultrathin, Lightweight, and Wearable Li-O2 Battery with High Robustness and Gravimetric/Volumetric Energy Density.

    Science.gov (United States)

    Liu, Tong; Xu, Ji-Jing; Liu, Qing-Chao; Chang, Zhi-Wen; Yin, Yan-Bin; Yang, Xiao-Yang; Zhang, Xin-Bo

    2017-02-01

    An ultrathin, lightweight, and wearable Li-O2 battery with a novel segmented structure is first fabricated by employing a "break up the whole into parts" strategy. Superior battery performance including low overpotential, high specific capacity, good rate capability, excellent cycle stability, and high gravimetric/volumetric energy density (294.68 Wh kg(-1) /274.06 Wh L(-1) ) is successfully achieved even under repeatedly various deformation.

  4. Expanding the Boundaries of Behavioral Integrity in Organizations

    Science.gov (United States)

    2010-07-01

    feedback, and acceptance of decisions. Positive trust outcomes even have been demonstrated in a more intimate relationship – between an online ... shopper and the e-retailer (Chen & Dibb, 2010). Even here, trust in the website predicted positive attitudes and intentions toward the company... online retail context: Exploring the antecedents and consequences. Psychology & Marketing, 27(4): 323-346. Chung-Herrera, B. G., & Lankau, M. J. 2005

  5. A study on sexual health knowledge, sexual attitudes and sex-related behaviors of university students in Hefei, China

    OpenAIRE

    Chi, Xinli; 遲新麗

    2014-01-01

    This present research aimed (1) to examine the level of sexual health knowledge, patterns of sexual attitudes and prevalence of sex-related behaviours among college students in contemporary China; (2) to explore factors predicting knowledge, attitude and behavior regarding sexuality; and (3) to assess gender differences in both characteristics and correlates. Based on data collected from 274 college students (167 male and 107 female) by the way of convenience sampling, in Hefei, China, Ph...

  6. Fat content of expressed breast milk: a case for quality control.

    OpenAIRE

    Spencer, S A; Hull, D

    1981-01-01

    Expressed breast milk used to feed preterm infants is precious and so, despite heterogeneity of composition, all available milk is used. A study of 274 samples of expressed breast milk supplied by preterm mothers and National Childbirth Trust donors showed pronounced variation in fat content as measured by the "creamatocrit" method. This was not due to differences between term and preterm mothers or between transitional and mature milk. The composition was affected by diurnal variation and me...

  7. Contributions to the Oceanography of the Western Alboran Sea.

    Science.gov (United States)

    1985-04-01

    Aerospaclal, Madrid, Spain . .. (4) Instituto Espanol de Oceanografia, Madrid, Spain (5) Members of the Donde Va Group are listed on page 22 L A..- 1PREFACE...October 1983. Instituto Espanol de Oceanografia (extended abstracts in English, short abstracts in Spanish and English), 1984. Parrilla, G. and T.H...MA 02543 Gregorio Parrilla Instituto Espanol de Oceanografia, Alcala 27-4*, 28014, Madrid, Spain In 1982 we did two CTD surveys of the western Alboran

  8. United States National Security Interests and the Republic of Mexico.

    Science.gov (United States)

    1983-06-01

    The perceptions that have been colored by history are sharpened by differences and dispari- ties separating the two nations. Octavio Paz , a...Stoessel, Jr., "Foreign Policy Priorities in Asia," Current Policy, No. 274, (April 24, 1981), p. 1. 14 Octavio Paz , Mexico and the U.S.: Positions and... Paz expressed it, "our countries are neighbors condemned to live alongside each other." The relationship began even before the two nations existed

  9. Other endocrinologic disorders

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    2008405 Male pseudohermaphroditism due to 17β-hydroxysteroid dehydrogenase 3 deficiency. YANG Jun(杨军), et al. Shanghai Clin Endocrin & Metab Dis Center, Ruijin Hosp, Shanghai Jiaotong Univ, Shanghai 200025. Chin J Endocrinol Metab 2008;24(3):272-274. Objective To investigate the clinical and genetic characteristics in a patient with 17β-hydroxy-steroid dehydrogenase (17β-HSD) 3 deficiency

  10. A Comparative Study of Linkage Indexes: Co-assignee, Reciprocal Citation, Patent Coupling and Co-patent

    Directory of Open Access Journals (Sweden)

    Szu-chia Scarlett Lo

    2010-06-01

    Full Text Available Four indexes including co-assignees, reciprocal citation, patent coupling and co-patent were examined in this study to reveal the meanings of the correlations generated via different citation linkages. This study includes 6,274 genetic engineering patents, and 16 primary assignees identified by Bradford model analysis as the base for correlation analysis. The results show that there are four cluster types, including technological affiliated, technological competitor correlated, commercial collaborated and technological isolated.

  11. Manpower Management (Officer and Enlisted) AFSC 74XX/733XX

    Science.gov (United States)

    1989-03-01

    SIGNIFICANTLY CHANGED 94 E340 REVIEW MISSION STATEMENTS 94 E310 IDENTIFY ASSUMED OR INFERRED WORK 94 E331 RESEARCH HISTORY OF MANPOWER ACTIONS 90 E349... E331 RESEARCH HISTORY OF MANPOWER ACTIONS 100 N906 EVALUATE ORGANIZATIONAL STRUCTURES 100 E275 COLLECT WORKLOAD DATA 100 E274 COLLECT MAN-HOUR DATA...INFERRED WORK 89 E273 COLLECT FAMILIARIZATION INFORMATION 78 E331 RESEARCH HISTORY OF MANPOWER ACTIONS 78 E315 INTERVIEW WORK CENTER PERSONNEL 78

  12. Automated Intelligent Agents: Are They Trusted Members of Military Teams?

    Science.gov (United States)

    2008-12-01

    Engineering Mangagement, 50(3), 262- 274. Rempel , J. K., Holmes, J.G., and Zanna, M.P. (1985). Trust in close relationships . Journal of Personality...competency of the automation (Dassonville, 1996). Another sociologist, Rempel (1985), explains trust in three dimensions: predictability...differences between them. Trust between people is generally part of a social exchange relationship resulting from repeated interactions between people

  13. Anesthesia in a Combat Environment

    Science.gov (United States)

    1981-09-25

    1969 19. Stoelting RK, Reis RR, Longnecker DE: Hemodynamic responses to nitrous oxide-halothane and halothane in patients with valvular heart disease . Anesthesiology...274- 285, 1971 28. Stoelting RK, Gibbs PS: Hemodynamic effects of morphine and morphine- nitrous oxide in valvular heart disease and coronary artery...responses to nitrous oxide-halothane and halothane in patients with valvular heart disease , Anesthesiology 37:430-435, 1975 34. Price HL: Myocardial

  14. Works notice

    CERN Multimedia

    GS Department

    2009-01-01

    We would like to inform you that renovation work on the road lighting equipment will take place on the Meyrin site between 19 October and 18 December 2009. During this period, traffic will be disrupted on the Schrödinger, Perrin and Siegbahn roads, ie from Building 274 to Building 188. We request that you comply with the road signs and thank you for your understanding. GS-SEM Group

  15. Muscle Sympathetic Nerve Activity During Intense Lower Body Negative Pressure to Presyncope in Humans

    Science.gov (United States)

    2009-08-24

    Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology, 1996). As diastolic arterial pressure... dogs . Am J Physiol Heart Circ Physiol 274, H1099–H1105. Preiss G & Polosa C (1974). Patterns of sympathetic neuron activity associated with Mayer waves...Society of Cardiology and the North American Society of Pacing and Electrophysiology (1996). Heart rate variability: standards of measurement

  16. Reactions of H2O3 in the pulse-irradiated Fe(II)-O2 system

    DEFF Research Database (Denmark)

    Sehested, Knud; Bjergbakke, Erling; Lang Rasmussen, O.;

    1969-01-01

    G(Fe(III)] is measured in pulse-irradiated O2-saturated solutions of 20 to 160 μMFe(II), at the p H's 0.46, 1.51, and 2.74 H2SO4 and HClO4 and with dose rates between 1 and 8 krad/1 μsec pulse. Based on homogeneous kinetics, the results are interpreted by a system of 18 reactions. The formation...

  17. Conserved syntenic clusters of protein coding genes are missing in birds

    OpenAIRE

    Lovell, Peter V.; Wirthlin, Morgan; Wilhelm, Larry; Minx, Patrick; Lazar, Nathan H.; Carbone, Lucia; Warren, Wesley C.; Mello, Claudio V.

    2014-01-01

    Background Birds are one of the most highly successful and diverse groups of vertebrates, having evolved a number of distinct characteristics, including feathers and wings, a sturdy lightweight skeleton and unique respiratory and urinary/excretion systems. However, the genetic basis of these traits is poorly understood. Results Using comparative genomics based on extensive searches of 60 avian genomes, we have found that birds lack approximately 274 protein coding genes that are present in th...

  18. A National Strategy for an Uncertain Future

    Science.gov (United States)

    1990-05-01

    Introduction by Samuel B. Griffith, (London: Oxford University Press, 1963), p. 84. 2. Robert W. Komer, "Thinking About Strategy: A Practitioner’s...in US Strategy ed. Frank R. Barnett, B. Hugh Tovar , and Richard H. Shultz (Washington: National Defense University Press, 1984), p. 274. 6. Brian M...and with an Introduction by Samuel B. Griffith (London: Oxford University Press, 1963), p. 77. 18. Belisarius, 505-565. 74 .*. .•*r¶ •-"r

  19. Regional Fears of Western Primacy and the Future of U.S. Middle Eastern Basing Policy

    Science.gov (United States)

    2006-12-01

    would be a mistake to conclude that the Gulf Arabs will tolerate public disrespect indefinitely because of their present dependence. While the... disrespectful ways (as occurred during to Dubai Ports World controversy, to be discussed later). 47 The Gulf Arab states also have some extremely...connects Bahrain to Saudi Arabia and is used for over 2,300,000 car trips per year.274 A variety of Saudi tourists come to Bahrain via the causeway

  20. Dicty_cDB: SHA572 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available : 112 length of database: 80,480,566 effective HSP length: 17 effective length of query: 95 effective length... of database: 78,821,179 effective search space: 7488012005 effective search space used: 7488012005 T: 0 A: ... than 10.0: 0 length of query: 112 length of database: 55,409,929,374 effective HSP length: 22 effective length of query: 90 effectiv...e length of database: 54,274,350,600 effective search space: 4884691554000 effective

  1. Difference and ratio plots

    DEFF Research Database (Denmark)

    Svendsen, Anders Jørgen; Holmskov, U; Bro, Peter

    1995-01-01

    hitherto unnoted differences between controls and patients with either rheumatoid arthritis or systemic lupus erythematosus. For this we use simple, but unconventional, graphic representations of the data, based on difference plots and ratio plots. Differences between patients with Burkitt's lymphoma...... and systemic lupus erythematosus from another previously published study (Macanovic, M. and Lachmann, P.J. (1979) Clin. Exp. Immunol. 38, 274) are also represented using ratio plots. Our observations indicate that analysis by regression analysis may often be misleading....

  2. Determing the Time Dependence of Electrical Gradients in Railguns using the Transmission Line

    Science.gov (United States)

    2008-09-01

    Phys., 40, 274-283. Feynman , R., Leighton, R., and Sands, M. 1964: The Feynman Lectures in Physics vol II, 3rd ed. Addison Wesley, 238 pp...2) This is similar to the familiar transmission line equation ( Feynman , et al, 1964) relating the gradient of the voltage along a transmission...strong function of time (skin effect) while LX is relatively insensitive to time. We attribute this to fundamental differences in the physics of the

  3. Urinary albumin in space missions

    DEFF Research Database (Denmark)

    Cirillo, Massimo; De Santo, Natale G; Heer, Martina

    2002-01-01

    Proteinuria was hypothesized for space mission but research data are missing. Urinary albumin, as index of proteinuria, was analyzed in frozen urine samples collected by astronauts during space missions onboard MIR station and on ground (control). Urinary albumin was measured by a double antibody...... radioimmunoassay. On average, 24h urinary albumin was 27.4% lower in space than on ground; the difference was statistically significant. Low urinary albumin excretion could be another effect of exposure to weightlessness (microgravity)....

  4. Loss and gain cycles? A longitudinal study about burnout, engagement and self-efficacy

    OpenAIRE

    Susana Llorens-Gumbau; Marisa Salanova-Soria

    2014-01-01

    The present longitudinal study (two waves), conducted on a population of 274 secondary-school teachers, expands on previous research on burnout and work engagement. Accordingly, the effect of organizational factors (obstacles, facilitators) as well as personal resources (self-efficacy) on burnout and engagement is tested longitudinally following the Social Cognitive Theory. More specifically, we test the loss and gain cycles, and reciprocal relationships concerning burnout, engagement, and se...

  5. Biotechnology Symposium

    Science.gov (United States)

    1990-10-01

    implant device is dependent in large part upon the quality and vitality of bone remodelling around the bone postop- ACETABULUM eratively. Bone resorption...Model of the Residual Strength and Life of Fatigue-loaded Composite Coupons," Composite Materials: Fatigue and Fracture . STP 907, H.T. Hahn, ed., ASTM...Materials Fatigue and Fracture . ASTM STP 907, D.J. Wilkins, Ed 1986, pp. 274- 297. 17. Tang, J.M., and Springer, G.S., Effects of Moisture and Temperature

  6. Órfãos de terapia medicamentosa: a administração de medicamentos por via intravenosa em crianças hospitalizadas

    OpenAIRE

    Peterlini, Maria Angélica Sorgini [UNIFESP; Chaud, Massae Noda [UNIFESP; Pedreira,Mavilde da Luz Gonçalves

    2003-01-01

    Descriptive study, developed at a general university hospital that aimed at verifying the number and types of IV drugs administered to children, the adequacy of their pharmacological presentation for pediatric use and the estimated costs of some drugs administration. In a period of 30 days, 8,245 drug doses were administered, with an average of 274.83 doses a day, and a yearly estimation of 98.940. The most used drugs were methylprednisolone, vancomycin, furosemide, ranitidine, penicillin, am...

  7. Phasic Dopaminergic Signaling and the Presymptomatic Phase of Parkinson’s Disease

    Science.gov (United States)

    2005-07-01

    anatomy and headinjury, ni magerostheintria do n s behavior. Behavioural Brain Research 28:259-274. head injury, damage to the intrinsic neurons Lindner...Gilliam P, Vaughn D, Wilcox RE (1982) nidate. Behavioural Brain Research , in press. Tactile extinction: Distinguishing between sensori- Fleming SM...test. Behavioural Brain Research , in press. decorticate rats. Behavioral Neuroscience 98:518-540. Greenough WT, Pass B, DeVoogd T (1976) The influ

  8. Strategic Plan for Electronic Commerce, Defense Personnel Support Center

    Science.gov (United States)

    1993-07-01

    AD-A274 243 Strategic Plan for Electronic Commerce Defense Personnel Support Center DTIC %!" . FLECTE .: UEC3 0 199 3 -I CUSTOMER SATISFACTION 93 12...220 3 &tiuini nm Best Available Copy Strategic Plan for Electronic Commerce Defense Personnel Support Center NTIS C? ~- j CUSTOMER Avao OrK...Concept of Operations and Projects ........... 6-4 Benefits and Costs of Electronic Commerce in the Medical Directorate

  9. Cancer Localization in the Prostate with F-18 Fluorocholine Position Emission Tomography

    Science.gov (United States)

    2008-01-01

    sterile in- ammatory lesion was much less than uptake in an im- lanted tumor, whereas the uptake of tritium-labeled deoxy- lucose was relatively increased...injection. Al- hough the renal excretion of FCH is not ideal for evaluations f the urinary tract, it has not proven intractable in actual ractice...emission tomography for prostate, bladder, and renal cancer. Semin Nucl Med 34:274-292, 2004 0. Shreve PD, Grossman HB, Gross MD, et al: Metastatic

  10. 服务器市场风云

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    戴尔推出三款新型服务器;捷洲推双校服务器新品I1-274TH;方正推出圆明MT100 1400四校服务器;联想发布最新四核服务器 性能提升近五成;IBM推出全新BladeCenter HT系统……

  11. Counterinsurgency Lessons from Colombia: An Assessment of the Colombian Army Transformation from 1998 to 2010

    Science.gov (United States)

    2014-12-01

    Consolidacion” [The patriot plan: The basis for the consolidation plan], Revista Fuerzas Armadas 76, no. 205 (April 2008), 21. 58...insurgents. 274 Luis Carlos Villegas, “Seguridad en Colombia: Clave Para el Desarrollo” [Security in Colombia: Key to development], Revista Fuerzas...consolidation plan]. Revista Fuerzas Armadas 76, no. 205 (April 2008): 19‒25. 78 Nagl, John A. Learning to Eat Soup with a Knife: Counterinsurgency

  12. Antiviral phenolics from the leaves of Cleistocalyx operculatus

    DEFF Research Database (Denmark)

    Ha, Thi Kim Quy; Dao, Trong Tuan; Nguyen, Ngoc Hieu

    2016-01-01

    different influenza viruses, including H1N1, H9N2, novel H1N1, and oseltamivir-resistant novel H1N1 (H274Y mutation) expressed in HEK293 cells (IC50 values ranging from 5.07 ± 0.94 μM to 9.34 ± 2.52 μM, respectively). Kinetic experiments revealed the non-competitive inhibitory mode of both compounds 6 and 8...

  13. Combat Aircraft Noise held in Bonn, Germany on 23-25 October 1991 (Le Bruit Genere par les Avions de Combat)

    Science.gov (United States)

    1992-04-01

    Rapport ISL R 114/77 (1977). 161 A. UIEDZWIEKI, H.S. RISNER Subjective loundness of *minimized" sonic boom wave forms. JASA, 64 (1978). (71 G. JANSEN ...Beoinflussung des Nachtschlafe durch Fluqzeuq mnall. Rapport ISL 2/74 (1974). 181 G. JANSEN , B. GRIEFAHN Exp•rimentalle Untersuchungen zum Problem der...empirical nately, jet speeds and jet temperatures of modem high perfor- SAE method. However, two important results of the theo - mance military aircraft

  14. A Task-Based Analysis of Information Requirements of Tactical Maps

    Science.gov (United States)

    1979-08-01

    of all built-up areas, but also feature locations such as the following: 4-10 (1) House. (2) Hut. (3) Railway station. (4) Youth hostel . (5) Hospital...Paper 274, June 1976. Hooper, K. and Cuff, D. Superfeatures of the UCSC Environment. University of California (Santa Cruz, CA), Unpublished Manuscript...New York: Wiley, 1978. Robinson, A.H. and Petchenik, B.B. The Nature of Maps. Chicago: The University of Chicago Press, 1976. Sheppard, D. and Adams, J

  15. 2010 Special Operations Forces Industry Conference Held in Tampa, Florida on June 15-17, 2010

    Science.gov (United States)

    2010-06-17

    Street Tampa, Florida 33602 (813) 274-8511 Marriott Waterside Hotel 700 South Florida Avenue Tampa, Florida 33602 (813) 221-4900 TAMPA CONVENTION CENTER...Ballroom A Senior Industry Executive Forum Rooms 15-16 Continental Breakfasts Ballroom D MARRIOTT WATERSIDE HOTEL SOFball Reception Grand Ballroom...Period of Performance Milestones Point of Contact Funding Current Contract/OEM Opportunities Next 12-18 Months BACKPACK : Follow-on 5 year IDIQ

  16. Significant association between ABO blood group and pancreatic cancer

    Institute of Scientific and Technical Information of China (English)

    Julia; B; Greer; Mark; H; Yazer; Jay; S; Raval; M; Michael; Barmada; Randall; E; Brand; David; C; Whitcomb

    2010-01-01

    AIM:To evaluate whether the ABO blood group is related to pancreatic cancer risk in the general population of the United States.METHODS:Using the University of Pittsburgh's clinicalpancreatic cancer registry,the blood donor database from our local blood bank (Central Blood Bank),and the blood product recipient database from the regional transfusion service (Centralized Transfusion Service) in Pittsburgh,Pennsylvania,we identified 274 pancreatic cancer patients with previously determined serological ABO bloo...

  17. Understanding Mobile Code and Secure Execution Environments

    Science.gov (United States)

    2006-02-21

    Lecture Notes in Computer Science . Springer-Verlag, 2003. " Matthew...mobile agents. In Secure Internet Programming, number 1603 in Lecture Notes in Computer Science , pages 261-274. Springer-Verlag Inc., New York, NY, USA...cryptography. In M. Joye, editor, Topics in Cryptography-CT-RSA 󈧇, volume 2612 of Lecture Notes in Computer Science . Springer-Verlag, 2003. [5] Carl

  18. Domain Modeling: NP_937793.1 [SAHG[Archive

    Lifescience Database Archive (English)

    Full Text Available NP_937793.1 chr5 Crystal structure of putative arylsulfatase from escherichia coli p3ed4d_ chr5/NP_937793....1/NP_937793.1_holo_20-459.pdb blast 52S,53Q,54V,261K,274N,275I,276R,421T,422N,424W,455K,456F,457P,458E,459I UNL 0 ...

  19. References to the paraphilias and sexual crimes in the Bible.

    Science.gov (United States)

    Aggrawal, Anil

    2009-04-01

    While writing a book on paraphilias, the author made a thorough search of early references to paraphilias in literature, especially the Bible. Surprisingly just one published paper was available in the literature having any discussion on the references of paraphilia in the Bible, and that too was in French. [Bieder J. The polymorphous sexual deviant: a reading of Freud and the Bible. Ann Med Psychol (Paris) 1973;2(2):274-81 [in French

  20. Evaluation of buffy-coat microscopy for the early diagnosis of bacteraemia.

    OpenAIRE

    Coppen, M. J.; Noble, C J; Aubrey, C

    1981-01-01

    Three hundred and sixty samples of blood from 230 hospital patients were examined and compared with the results of simultaneous blood culture to determine the value of buffy-coat microscopy in detecting bacteraemia. One observer found 86 positive smears, 12 of which were from patients with positive blood cultures and 74 from patients with negative blood cultures. The buffy-coat smear was negative in 274 specimens, 8 of which yielded positive blood cultures. A second observer considered that o...

  1. A Survey and Analysis of Normal Ionospheric Absorption Measurements Obtained from Radio Pulse Reflections

    Science.gov (United States)

    1970-09-01

    variation of equatorial absorption is somewhat unexpected, since the midday solar radiation is almost constant at these latitudes. This anomalous behavior...loss study at 5 MHz, using a radiated power of 39 kw. Open circuit voltage was recorded at the receiver and the hourly median decibel values of...Regions," Journal of Atmospheric and Terrestrial Physics, Vol. 23, December 1961, pp. 260-274. Harnischmacher, E., "L’influence solaire sur la couche

  2. Use of Telemorace Inhibition in Combination with Anti-Cancer Drugs to Induce Cell Death in Tumor Cells

    Science.gov (United States)

    2006-08-01

    ase expressed in Saccharomyces cerevisiae . J Biol Chem 1999;274: 38027–31. 36. Kim NW, Piatyszek MA, Prowse KR, et al. Specific association of...indicating that estrogen receptor-positive tumors can be treated with well tolerated therapies, whereas estrogen-negative tumors are in greater need...days of treatment and fixed with ice-cold ethanol . Before analysis, cells were centrifugated, resuspended in 500ml of cold PBS containing 200 mg/ml of

  3. Understanding obsessive-compulsive personality disorder in adolescence: a dimensional personality perspective

    OpenAIRE

    Aelterman, Nathalie; Decuyper, Mieke; Fruyt, Filip De

    2010-01-01

    The validity of the Axis II Obsessive-Compulsive Personality Disorder (OCPD) category and its position within the Cluster C personality disorder (PDs) section of the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV, APA, 2000) continues to be a source of much debate. The present study examines the associations between general and maladaptive personality traits and OCPD symptoms, prior to and after controlling for co-occurring PD variance, in a general population sample of 274 Fle...

  4. Mental Health of Students in Sports School%体校学生心理健康状况调查

    Institute of Scientific and Technical Information of China (English)

    蔡先锋

    2005-01-01

    本研究采用《心理健康诊断测试》(MHT)对江苏省体校814名学生进行了问卷调查,回收有效问卷681份,占80.26%,男生407人,女生274人,高中生431人,初中生250人。

  5. Simultaneous Determination of Amlodipine Besylate and Atorvastatin Calcium in Binary Mixture by Spectrofluorimetry and HPLC Coupled with Fluorescence Detection

    OpenAIRE

    Bahia A. Moussa; Asmaa A. El-Zaher; Mahrouse, Marianne A.; Ahmed, Maha S.

    2013-01-01

    Caduet tablets are novel prescription drug that combines amlodipine besylate (AM) with atorvastatin calcium (AT). A spectrofluorimetric and an HPLC-fluorescence detection methods were developed for simultaneous determination of both drugs in tablets. In the spectrofluorimetric method, native fluorescence of AM and AT were measured in methanol at 442 and 369 nm upon excitation at 361 and 274 nm, respectively. The emission spectrum of each drug reveals zero value at the emission wavelength of t...

  6. The Effects of City Image, Event Fit, and Word-of-mouth Intention towards the Host City of an International Sporting Event

    OpenAIRE

    Daichi Oshimi; Munehiko Harada

    2016-01-01

    This study (1) develops a structure of host city image, (2) verifies the antecedents and consequences of host city image, and (3) predicts spectators’ positive word-of-mouth (WOM) intention towards the host city through structural equation modeling. With the cooperation of the local city government, questionnaires were distributed to spectators of the 2014 Tour de France Saitama Criterium in Japan. Convenience sampling was utilized, and 274 usable questionnaires were obtained. First, the resu...

  7. Strategic Appraisal 1996.

    Science.gov (United States)

    1996-01-01

    Haiti 274 Mexico 276 Venezuela 277 Panama 278 Brazil. 279 Drug Interdiction 280 Conclusion 281 Chapter Twelve, AshleyJ. Tellis SOUTH ASIA... Mexico or Saudi Arabia—and others might so chal- lenge American values as practically to require U.S. military involve- ment. The United States...slowly and grudgingly, but he has almost surely made his basic strategic decision to reach a peaceful settlement—even if the posturing and haggling will

  8. U.S. Military Technology Dependence: The Hidden Vulnerability to National Security

    Science.gov (United States)

    2016-06-10

    18 J. Snell, “Chaos Theory and Post Modernism .” Education, 130(2), (February 2009), 274-276. http...Jennifer Daryl, and J. Macgregor Wise. "Culture and Technology." A Primer, New 2005. Snell, J., “Chaos Theory and Post Modernism ”, Education, 130(2...heated debates over the ethics of their use in war; however, today drones are no longer for military use only. Recently enthusiasts flying drones all

  9. MICROBIOLOGICAL AND CHEMICAL TESTING OF FOOD SNAILS MARKETEDS IN SARDINIA

    Directory of Open Access Journals (Sweden)

    T. Tedde

    2009-09-01

    Full Text Available A total of 29 samples of snails belonging to the species Helix aspersa, Helix aperta and Helix vermiculata were analysed for the presence of Salmonella spp. and Clostridium perfringens; Cadmium and Lead concentrations were determined by ICP-MS. One sample contained Salmonella sp.; Clostridium perfringens were not detected. The means of toxic metals (expressed as mg/Kg wet weight were the following: Cd 0,995, Pb 0,274. Key words

  10. Aquatic Toxicity Screening of an ACWA Secondary Waste, GB-Hydrolysate

    Science.gov (United States)

    2009-01-01

    toxicity the bioassay must include a minimum of four dilutions exhibiting a dose response, plus a control consisting of V.fischeri bioluminescent...typically used in the preliminary screening process and is not intended to be a substitute for risk assessment. This system assigns a score (0-9; 9 being...Aquatic Toxicological Research with Organophosphate Insecticides. Ecotoxicology Environmental Saf 1991, 21 (3), pp 266-274. 10. Maas, J.L. Toxicity of

  11. On the Effectiveness of Military Institutions: Historical Case Studies from World War I, The Interwar Period, and World War II. Volume 3. World War II

    Science.gov (United States)

    1986-04-01

    as possible) and bluster: ’education fla cultural counts for nothing’. "L4 cultura might indeed count for nothing until It came time to navigate 3 in...1007, Cant. Z 506) (Fortunato Minniti, ’La politica Industziale 3 del Ministero dell*Aeronautica. Mercato, Planificazione, Sviluppo (1935-1943),’ Storia...remark: Minnici, ’La politica Industriale," p. 274. 12. See D’Avanzo, Ali e voltrone, pp. 334-35, tot an energetic but undocumented statement of the

  12. Whole genome shotgun sequencing of Brassica oleracea and its application to gene discovery and annotation in Arabidopsis

    OpenAIRE

    Ayele, Mulu; Haas, Brian J.; Kumar, Nikhil; Wu, Hank; Xiao, Yongli; Van Aken, Susan; Utterback, Teresa R.; WORTMAN, Jennifer R.; White, Owen R.; Town, Christopher D

    2005-01-01

    Through comparative studies of the model organism Arabidopsis thaliana and its close relative Brassica oleracea, we have identified conserved regions that represent potentially functional sequences overlooked by previous Arabidopsis genome annotation methods. A total of 454,274 whole genome shotgun sequences covering 283 Mb (0.44×) of the estimated 650 Mb Brassica genome were searched against the Arabidopsis genome, and conserved Arabidopsis genome sequences (CAGSs) were identified. Of these ...

  13. The influence of distance and quality of care on place of delivery in rural Ghana

    OpenAIRE

    2016-01-01

    Facility delivery is an important aspect of the strategy to reduce maternal and newborn mortality. Geographic access to care is a strong determinant of facility delivery, but few studies have simultaneously considered the influence of facility quality, with inconsistent findings. In rural Brong Ahafo region in Ghana, we combined surveillance data on 11,274 deliveries with quality of care data from all 64 delivery facilities in the study area. We used multivariable multilevel logistic regressi...

  14. Understanding obsessive-compulsive personality disorder in adolescence: a dimensional personality perspective

    OpenAIRE

    Aelterman, Nathalie; Decuyper, Mieke; De Fruyt, Filip

    2010-01-01

    The validity of the Axis II Obsessive-Compulsive Personality Disorder (OCPD) category and its position within the Cluster C personality disorder (PDs) section of the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV, APA, 2000) continues to be a source of much debate. The present study examines the associations between general and maladaptive personality traits and OCPD symptoms, prior to and after controlling for co-occurring PD variance, in a general population sample of 274 Fle...

  15. Computer-Aided Process and Tools for Mobile Software Acquisition

    Science.gov (United States)

    2013-07-30

    deploy mobile devices” ( Kenyon , 2012a). The Defense Information Systems Agency (DISA) has opened a program office and issued a request for information to...solicit ideas from industry for ways to provide the mobile device management (MDM) services and to run an applications store ( Kenyon 2012b), and...8(3), 231–274. Kenyon , H. (2012a, January 11). Army sets tone for government’s mobile enterprise with Android. Retrieved from http

  16. Blind One-Bit Compressive Sampling

    Science.gov (United States)

    2013-01-17

    notation and recalling some background from convex analysis . For the d-dimensional Euclidean space Rd, the class of all lower semicontinuous convex...compressed sensing, Applied and Computational Harmonic Analysis , 27 (2009), pp. 265 – 274. [3] P. T. Boufounos and R. G. Baraniuk, 1-bit compressive sensing...Convergence analysis of the algorithm is presented. Our approach is to obtain a sequence of optimization problems by successively approximating the ℓ0

  17. Challenges and opportunities for checkpoint blockade in T-cell lymphoproliferative disorders

    OpenAIRE

    Phillips, Tycel; Devata, Sumana; Wilcox, Ryan A.

    2016-01-01

    The T-cell lymphoproliferative disorders are a heterogeneous group of non-Hodgkin’s lymphomas (NHL) for which current therapeutic strategies are inadequate, as most patients afflicted with these NHL will succumb to disease progression within 2 years of diagnosis. Appreciation of the genetic and immunologic landscape of these aggressive NHL, including PD-L1 (B7-H1, CD274) expression by malignant T cells and within the tumor microenvironment, provides a strong rationale for therapeutic targetin...

  18. The Evolution of the Mexican Military: From the Mexican Revolution In 1910 to 2014

    Science.gov (United States)

    2015-03-01

    E. French (eds.), Rituals of Rule, Rituals of Resistance: Public Celebrations and Popular Culture in Mexico (Wilmington, DE: Rowman & Littlefield...Alicia Hernández Chávez, “Origen y ocaso del ejército porfiriano,” Historia Mexicana 39 (1989), 285. 72 Camp, “ Mexico ,” 274–275. 25...Popular Culture in Mexico . Wilmington: Rowman & Littlefield Publishers 1994. Camp, Roderic Ai. Generals in the Palacio: The Military in Modern

  19. METAMORPHIC PETROLOGY

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    <正>20090911 Chen Junlu(Xi’an Institute of Geology and Mineral Resources,China Geological Survey,Xi’an 710054,China);Xu Xueyi Geological Features and SHRIMP U-Pb Zircon Age of the Yanwan-Yinggezui Ophiolitic M(?)lange in the Taibai Area,Westren Qinling,China(Geogolical Bulletin of China, ISSN1671-2552,CN11-4648/P,27(4),

  20. Utopia Cracks and Polygons

    Science.gov (United States)

    2003-01-01

    MGS MOC Release No. MOC2-339, 23 April 2003This Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) image shows a pattern of polygonal cracks and aligned, elliptical pits in western Utopia Planitia. The picture covers an area about 3 km (about 1.9 mi) wide near 44.9oN, 274.7oW. Sunlight illuminates the scene from the left.

  1. Social media-based systems: an emerging area of information systems research and practice

    OpenAIRE

    Aziz, Hazman; Faiza, Ahmad Fahmi

    2014-01-01

    This article presents a review of the social media-based systems; an emerging area of information system research, design, and practice shaped by social media phenomenon. Social media-based system (SMS) is the application of a wider range of social software and social media phenomenon in organizational and non-organization context to facilitate every day interactions. To characterize SMS, a total of 274 articles (published during 2003–2011) were analyzed that were classified as computer scien...

  2. TANGGUNG JAWAB NEGARA TERHADAP PENCEMARAN UDARA AKIBAT POLUSI ASAP LINTAS BATAS (TRANSBOUNDARY HAZE POLLUTION) DALAM KASUS MALAYSIA DAN SINGAPURA

    OpenAIRE

    -, AVEL HAEZER M

    2016-01-01

    2016 AVEL HAEZER MATANDE, NIM : B111 12 274, Tanggung Jawab Negara Terhadap Pencemaran Udara Akibat Polusi Asap Lintas Batas (Transboundary Haze Pollution) Dalam Kasus Malaysia dan Singapura di bawah bimbingan S.M.Noor selaku pembimbing I dan Birkah Latif selaku pembimbing II. Penelitian ini bertujuan untuk mengetahui dua hal: pertama, untuk mengetahui 1. Bagaimanakah dampak polusi kabut asap yang terjadi di Riau terhad...

  3. Domain Modeling: NP_005300.1 [SAHG[Archive

    Lifescience Database Archive (English)

    Full Text Available NP_005300.1 chr8 AAT-like d1xi9d_ chr8/NP_005300.1/NP_005300.1_holo_29-487.pdb blas...t 123Y,159G,160A,161S,189Y,192Y,240I,242P,244N,272D,274V,275Y,294M,310H,311S,313S,319E,323R,413Y 189Y,314K PLP 0 ...

  4. Title VI Lands Cultural Resource Management Plan Contract No. W9128F-10-P-0092

    Science.gov (United States)

    2014-12-12

    pendant triangles, diamonds , trapezoids, inverted "turkey tracks" and conventionalized deer, maize and tree motifs (Johnson 1969:274; Anfinson 1979:88...multiple herringbone or nested chevron motifs; or, occasionally, rainbow motifs and filled diamonds . Lip decoration is almost ubiquitous; plain lips are...edited by Stephen C. Porter , pp. 3-37. Late-Quaternary Environments of the United States, Vol. 1, edited by H. E. Wright, Jr. University of

  5. Influences of Nutrition and Physical Forces on Bone Structure/Function Properties

    Science.gov (United States)

    2005-10-01

    Michigan, 930 N. University Avenue, Ann Arbor, MI 48109-1055, USA 2Department of Orthodontics and Pediatric Dentistry, University of Michigan School of...Cole, W. G. Advances in osteogenesis imperfecta. Clinical orthopaedics and related research 401, 6-16. 2002. 5. Marini, J. C. Osteogenesis Imperfecta... journal of biological chemistry 274(53), 37923-37931. 99. 10. Kozloff, K. M. , Carden, A., Bergwitz, C., Forlino, A., Uveges, T. E., Morris, M. D

  6. N-(4-Chloro-3-nitro-phen-yl)succinamic acid.

    Science.gov (United States)

    Chaithanya, U; Foro, Sabine; Gowda, B Thimme

    2012-04-01

    In the title compound, C(10)H(9)ClN(2)O(5), the nitro group is significantly twisted out of the plane of the benzene ring to which it is attached [dihedral angle = 27.4 (6)°]. In the crystal, mol-ecules are linked into centrosymmetric dimers via pairs of O-H⋯O hydrogen bonds. These dimers are further linked by N-H⋯O hydrogen bonds into double chains running along the a axis.

  7. Parallel Human and Animal Models of Blast- and Concussion-Induced Tinnitus and Related Traumatic Brain Injury (TBI)

    Science.gov (United States)

    2013-01-01

    not be feasible without episodic representation to form a spatial environment map ( Eichenbaum , 1999). Moreover, current study is the first study to...and GABA(B) receptors in the regulation of the nucleus accumbens dopamine response to stress. Brain research. 1150, 62-8. Eichenbaum , H., 1999. The...and hyperactivity following cochlear damage. HearRes 147, 261-274. Sanderson, K.L., Raghupathi, R., Saatman, K.E., Martin , D., Miller, G., and

  8. Stress-relaxation tests in the work-hardening regime of tungsten single crystals below 300 K

    Energy Technology Data Exchange (ETDEWEB)

    Brunner, D. [Max-Planck-Institut fuer Metallforschung, Heisenbergstrasse 3, 70569 Stuttgart (Germany)], E-mail: d.brunner@mf.mpg.de

    2008-06-15

    The influence of work hardening on the results of stress-relaxation tests was studied for highly pure tungsten single crystals isothermally deformed at four temperatures of 274, 241, 131, and 78 K. A method accounting for strong work hardening on the determination of the strain-rate sensitivity from stress-relaxation tests is introduced by establishing special diagrams of SR tests denoted as YX diagrams.

  9. Predictors of Metabolic Syndrome in the Iranian Population: Waist Circumference, Body Mass Index, or Waist to Hip Ratio?

    OpenAIRE

    Mojgan Gharipour; Nizal Sarrafzadegan; Masoumeh Sadeghi; Elham Andalib; Mohammad Talaie; Davood Shafie; Esmaiel Aghababaie

    2013-01-01

    This study aimed to investigate whether body mass index (BMI), waist circumference (WC), or waist to hip ratio (WHR) could be a better predictor of metabolic syndrome and, if so, what would be the cutoff points for these surrogates to appropriately differentiate metabolic syndrome in different age and sex subgroups. Methods. The present cross-sectional study was conducted on a sample of Isfahan Cohort Study (ICS). In total, 468 individuals (194 with and 274 subjects without metabolic syndrome...

  10. Induction of tolerance against the arthritogenic antigen with type-II collagen peptide-linked soluble MHC class II molecules

    Science.gov (United States)

    Park, Yoon-Kyung; Jung, Sundo; Park, Se-Ho

    2016-01-01

    In murine collagen-induced arthritis (CIA), self-reactive T cells can recognize peptide antigens derived from type-II collagen (CII). Activation of T cells is an important mediator of autoimmune diseases. Thus, T cells have become a focal point of study to treat autoimmune diseases. In this study, we evaluated the efficacy of recombinant MHC class II molecules in the regulation of antigen-specific T cells by using a self peptide derived from CII (CII260-274; IAGFKGEQGPKGEPG) linked to mouseI-Aq in a murine CIA model. We found that recombinant I-Aq/CII260-274 molecules could be recognized by CII-specific T cells and inhibit the same T cells in vitro. Furthermore, the development of CIA in mice was successfully prevented by in vivo injection of recombinant I-Aq/CII260-274 molecules. Thus, treatment with recombinant soluble MHC class II molecules in complex with an immunodominant self-peptide might offer a potential therapeutic for chronic inflammation in autoimmune disease such as rheumatoid arthritis. [BMB Reports 2016; 49(6): 331-336 PMID:26779996

  11. Alternating Hemiplegia of Childhood mutations have a differential effect on Na(+),K(+)-ATPase activity and ouabain binding.

    Science.gov (United States)

    Weigand, Karl M; Messchaert, Muriël; Swarts, Herman G P; Russel, Frans G M; Koenderink, Jan B

    2014-07-01

    De novo mutations in ATP1A3, the gene encoding the α3-subunit of Na(+),K(+)-ATPase, are associated with the neurodevelopmental disorder Alternating Hemiplegia of Childhood (AHC). The aim of this study was to determine the functional consequences of six ATP1A3 mutations (S137Y, D220N, I274N, D801N, E815K, and G947R) associated with AHC. Wild type and mutant Na(+),K(+)-ATPases were expressed in Sf9 insect cells using the baculovirus expression system. Ouabain binding, ATPase activity, and phosphorylation were absent in mutants I274N, E815K and G947R. Mutants S137Y and D801N were able to bind ouabain, although these mutants lacked ATPase activity, phosphorylation, and the K(+)/ouabain antagonism indicative of modifications in the cation binding site. Mutant D220N showed similar ouabain binding, ATPase activity, and phosphorylation to wild type Na(+),K(+)-ATPase. Functional impairment of Na(+),K(+)-ATPase in mutants S137Y, I274N, D801N, E815K, and G947R might explain why patients having these mutations suffer from AHC. Moreover, mutant D801N is able to bind ouabain, whereas mutant E815K shows a complete loss of function, possibly explaining the different phenotypes for these mutations.

  12. Measurement of the Survival Probabilities for Hot Fusion Reactions

    CERN Document Server

    Yanez, R; Yao, L; Barrett, J s; Zhu, S; Back, B B; Khoo, T L; Alcorta, M; Albers, M

    2014-01-01

    We have studied the fission-neutron emission competition in highly excited $^{274}$Hs (Z=108) (where the fission barrier is due to shell effects) formed by a hot fusion reaction. Matching cross bombardments ($^{26}$Mg + $^{248}$Cm and $^{25}$Mg + $^{248}$Cm) were used to identify the properties of first chance fission of $^{274}$Hs. A Harding-Farley analysis of the fission neutrons emitted in the $^{25,26}$Mg + $^{248}$Cm was performed to identify the pre- and post-scission components of the neutron multiplicities in each system. ($\\Gamma$$_{n}$/$\\Gamma$$_{t}$) for the first chance fission of $^{274}$Hs (E$^{\\ast}$ = 63 MeV) is 0.89 $\\pm$ 0.13, i.e., $\\sim$ 90 $%$ of the highly excited nuclei survive.The high value of that survival probability is due to dissipative effects during de-excitation. A proper description of the survival probabilities of excited superheavy nuclei formed in hot fusion reactions requires consideration of both dynamic and static (shell-related) effects.

  13. Toxicity evaluation of prodigiosin from Serratia marcescens in a Caenorhabditis elegans model

    Science.gov (United States)

    Seah, Siew-Wei; Nathan, Sheila; Wan, Kiew-Lian

    2016-11-01

    Serratia marcescens produces several secondary metabolites, including a red antimicrobial pigment, prodigiosin. There is considerable interest in prodigiosin and its derivatives due to their anticancer and immunosuppressive properties. Prodigiosin has also become the main choice of red dye in textiles. As prodigiosin has potentially high commercial value, there is a demand to develop high-throughput and cost-effective bioprocesses for prodigiosin production. However little is still known about its toxicity. This study was carried out to investigate the toxicity effect of prodigiosin. To determine if prodigiosin was potentially toxic to eukaryotic systems, the S. marcescens ATCC 274 wild type (Sma 274) and the non-prodigiosin producer S. marcescens Bizio WF mutant ATCC 29635 (WF mutant) were grown under the optimised conditions for prodigiosin production and fed to the nematode Caenorhabditis elegans. The mean time to death (TDmean) for Sma 274-infected worms assayed on agar was 112.6 hours while the WF mutant culture had a TDmean of 104.4 hours. However, the nematode killing kinetics were not significantly different between the prodigiosin-producing and non-producing S. marcescens strains (p>0.05). In lieu of its non-toxic property, prodigiosin has the potential to be developed for safe therapeutic applications and as a safe environmental friendly bio-dye.

  14. Templated Aggregation of TAR DNA-binding Protein of 43 kDa (TDP-43) by Seeding with TDP-43 Peptide Fibrils*

    Science.gov (United States)

    Shimonaka, Shotaro; Nonaka, Takashi; Suzuki, Genjiro; Hisanaga, Shin-ichi; Hasegawa, Masato

    2016-01-01

    TAR DNA-binding protein of 43 kDa (TDP-43) has been identified as the major component of ubiquitin-positive neuronal and glial inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Aggregation of TDP-43 to amyloid-like fibrils and spreading of the aggregates are suggested to account for the pathogenesis and progression of these diseases. To investigate the molecular mechanisms of TDP-43 aggregation, we attempted to identify the amino acid sequence required for the aggregation. By expressing a series of deletion mutants lacking 20 amino acid residues in the C-terminal region in SH-SY5Y cells, we established that residues 274–313 in the glycine-rich region are essential for aggregation. In vitro aggregation experiments using synthetic peptides of 40 amino acids from this sequence and adjacent regions showed that peptides 274–313 and 314–353 formed amyloid-like fibrils. Transduction of these fibrils induced seed-dependent aggregation of TDP-43 in cells expressing wild-type TDP-43 or TDP-43 lacking nuclear localization signal. These cells showed different phosphorylated C-terminal fragments of TDP-43 and different trypsin-resistant bands. These results suggest that residues 274–353 are responsible for the conversion of TDP-43 to amyloid-like fibrils and that templated aggregation of TDP-43 by seeding with different peptides induces various types of TDP-43 pathologies, i.e. the peptides appear to act like prion strains. PMID:26887947

  15. Oxygen and hydrogen ion abundance in the near-Earth magnetosphere: Statistical results on the response to the geomagnetic and solar wind activity conditions

    CERN Document Server

    Kronberg, Elena A; Daly, Patrick W; Grigorenko, Elena E; Kistler, Lynn; Fränz, Markus; Dandouras, Iannis

    2012-01-01

    The composition of ions plays a crucial role for the fundamental plasma properties in the terrestrial magnetosphere. We investigate the oxygen-to-hydrogen ratio in the near-Earth magnetosphere from -10 RE274 keV O+ ion intensities, relative to the corresponding hydrogen intensities; (3) In contrast to ~10 keV ions, the >274 keV O+ ions show the strongest acceleration during growth phase and not during the expansion phase itself. This suggests a connection between the energy input to the magnetosphere and the effective energization of energetic ions during growth phase; (4) The ratio between quiet and disturbed times for the intensities of ion ionospheric outflow is similar to those observed in the near-Earth magnetosphere at >274 keV. Therefore, the increase of the energetic ion intensity during disturbed time is more likely due to the intensification than to the more effective acceleration of the ionospheric source. In conclusion, the energization process in the near-Earth magnetosphere is mass dependent and...

  16. Glycogen synthase kinase 3 β activity is required for hBora/Aurora A-mediated mitotic entry.

    Science.gov (United States)

    Lee, Yu-Cheng; Liao, Po-Chi; Liou, Yih-Cherng; Hsiao, Michael; Huang, Chi-Ying; Lu, Pei-Jung

    2013-03-15

    The synthesis and degradation of hBora is important for the regulation of mitotic entry and exist. In G 2 phase, hBora can complex with Aurora A to activate Plk1 and control mitotic entry. However, whether the post-translational modification of hBora is relevant to the mitotic entry still unclear. Here, we used the LC-MS/MS phosphopeptide mapping assay to identify 13 in vivo hBora phosphorylation sites and characterized that GSK3β can interact with hBora and phosphorylate hBora at Ser274 and Ser278. Pharmacological inhibitors of GSK3β reduced the retarded migrating band of hBora in cells and diminished the phosphorylation of hBora by in vitro kinase assay. Moreover, as well as in GSK3β activity-inhibited cells, specific knockdown of GSK3β by shRNA and S274A/S278 hBora mutant-expressing cells also exhibited the reduced Plk1 activation and a delay in mitotic entry. It suggests that GSK3β activity is required for hBora-mediated mitotic entry through Ser274 and Ser278 phosphorylation.

  17. Health care costs in the last four years of life for private health plan beneficiaries in Brazil.

    Science.gov (United States)

    Ferraz, Marcos Bosi; Miranda, Isaura Cristina; Padovan, Jorge; de Soárez, Patricia Coelho; Ciconellil, Rozana

    2008-08-01

    To examine health care use and expenditures by Brazilians covered by private health care plans in the last four years of life. Health plan provider enrollee files and death certificate data were used for 274 health plan beneficiaries who died in 1998, 1999, and 2000. Resources used for a beneficiary in the year of death and in the three years prior to death were identified. Descriptive statistical analyses were used for clinical and socio-demographic characteristics and to describe the costs. Of the 274 deaths included in this analysis, 92 occurred in 1998, 82 in 1999, and 100 in 2000. Most of the deceased were males (61.4%). Distribution in terms of type of health plan coverage (full versus hospitalization-only coverage) was similar among beneficiaries (53% had hospitalization only and 47% had full coverage). The total health plan expenditure in the last four years of life for the 274 decedents was US$ 26,300,283 (US$ 12,287,723 for beneficiaries with hospitalization-only and US$ 14,012,560 for those with full coverage). Expenditures increased progressively in the four years preceding death. About 70% of medical expenses for decedents in the four years of this analysis were incurred in the last year of life. Relatively large amounts of health care resources are used by Brazilian private health plan participants in their last year of life, suggesting that specific strategies are needed to optimize the allocation of medical care resources for these patients.

  18. Identifikasi dan Kuantifikasi Metabolit Bakteri Pelarut Fosfat dan Pengaruhnya terhadap Aktivitas Rhizoctonia solani pada Tanaman Kedelai

    Directory of Open Access Journals (Sweden)

    Tri Candra Setiawati

    2008-09-01

    Full Text Available Phosphate solubilizing bacteria (PSB metabolites are organic acids, phosphomonoesterase enzyme (alkaline phosphatase and antibiotic, which is able to dissolve insoluble phosphate. Phosphate solubilizing bacteria used in this study was expected to suppress Rhizoctonia solani attacks. This experiment was aimed at (1 identifiying and quantifying PSB metabolites, and (2 examining their capability as biocontrol agent for Rhizoctonia solani in vitro and hydroponics soybean. This study was conducted in three stages. The first stage of this study was culturing two PSB isolates (Pseudomonas putida 27.4B and Pseudomonas diminuta in the Pikovskaya medium to analyze their metabolites. The second and third stage of this study was testing the antagonist of two bacteria to suppressed R. solani activity, which was conducted in vitro, and in hydroponics medium soybean as indicator plant. The results showed that P. putida 27.4B and P. diminuta produced organic acids i.e.: citrate, formic, succinic, acetic, propionate, butyrate, and oxalate. The totals of organic acids from each bacterium were 70,3 mg.kg-1 and 61,9 mg.kg-1. Production of alkaline phosphatase enzyme in Pikovskaya medium of P. Putida 27.4B was 11,71 ìg pNP .mL-1.h-1 and P. diminuta was 24,04 ìg pNP.mL-1.h-1. Concentration of this enzyme in soil medium was higher than that in Pikovskaya medium with 26,27 ìg pNP.g-1.h-1 and 39,03 ìg pNP.g-1.h-1 respectively. This study also showed that total concentration of antibiotics (tetracycline, oxitetracycline and penicillin produced by the PSB, were 3,2 ìg.mL-1 (P. putida 27.4B and 10,96 ìg.m1-1 (P. diminuta, respectively. The results from second stage of this study showed that by using in vitro, the reduced growth of R. solani was observed 58,35% with P. putida 27.4B and 41,96% with P. diminuta. In addition, inoculations of PSB in hydroponics medium reduced the fungal pathogenesis from 10,71% to 21,42% of pre and post emergence damping-off. Visually

  19. Establishment of triglyceride cut-off values to detect chylous ascites and pleural effusions.

    Science.gov (United States)

    Thaler, Markus A; Bietenbeck, Andreas; Schulz, Christoph; Luppa, Peter B

    2017-02-01

    Lipoprotein electrophoresis is the gold standard for the detection of chylous ascites and pleural effusions. It is, however, not suitable as a front-line test and not widely available. Most clinicians must rely solely on the quantitative determination of lipids. The aim of this work was to establish lipid cut-off values for the presence of chylomicrons in pleural and peritoneal fluid. Triglyceride and cholesterol levels from 113 peritoneal and 154 pleural fluid samples investigated for chylomicrons via lipoprotein electrophoresis were considered. Receiver operating characteristic analyses were performed and cut-off levels determined. 54 peritoneal and 59 pleural fluid samples were positive for chylomicrons. In peritoneal fluid, triglycerides and triglycerides/cholesterol ratio exhibited areas under the curve (AUC) not significantly different from each other, but significantly larger than cholesterol alone. The AUC for triglycerides in pleural fluid was significantly larger than the AUCs for cholesterol and the triglycerides/cholesterol ratio. Triglyceride cut-offs with maximum Youden-Index, sensitivity >95%, and specificity >95% were calculated to be 187, 148, and 246mg/dl (2.13, 1.69, and 2.80mmol/l) for peritoneal fluid, and 240, 94, and 240mg/dl (2.74, 1.07, and 2.74mmol/l) for pleural fluid. Triglyceride levels are the best parameter to detect chylous body fluids when lipoprotein electrophoresis is not available. Single-point triglyceride cut-offs of 187 and 240mg/dl (2.13 and 2.74mmol/l) or alternatively equivocal ranges of 148-246 and 94-240mg/dl (1.69-2.80 and 1.07-2.74mmol/l) were established for peritoneal and pleural fluid, respectively. Copyright © 2016 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.

  20. [Prevalence of vegetarians and vegetarian's health dietary behavior survey in Shanghai].

    Science.gov (United States)

    Mao, Xuanxia; Shen, Xiuhua; Tang, Wenjing; Zhao, Ye; Wu, Fan; Zhu, Zhenni; Tang, Qingya; Cai, Wei

    2015-03-01

    To assess the prevalence of vegetarians in the whole Shanghai population, and to know the vegetarians' brief and behavior on diet, nutrition and health. First, a multi-staged, stratified, clustered random sampling design was used. A total representative sample of 4 004 Shanghai resident subjects were asked if they were vegetarians and what type of vegetarian they were by a well-designed questionnaire. Second, from ten vegetarian restaurants located in Shanghai. 473 adult vegetarians completed a questionnaire about vegetarian status, among whom 274 vegetarians completed a detailed questionnaire about their brief and behaviors on diet, nutrition and health status. Of 4 004 subjects, 0.77% were vegetarians (0.45% were lacto-vegetarians and 0. 12% were vegans). The average age was 65. 0 years. 74. 2% of the vegetarians were female. Of 473 vegetarians, 70. 2% of the vegetarians had college or higher education. Compared to vegans, lacto-ovo-vegetarians were significantly younger and had higher educational level. The main reasons for choosing a vegetarian lifestyle were religion (49. 3%) and health (31. 3%). Furthermore, more vegan tend to be Buddhist. Vegetarians were more concerned about their health (209/274, 76. 5%) , the consumption of balance diets (183/274, 66. 8%). Comparing with lacto-ovo-vegetarians (58. 3%) more vegans (70. 4%) believed in that vegetarian diet is a kind of healthy dietary pattern and will not have any nutrients deficiency (P = 0. 037). Vegetarians consumed more healthy foods (e. g.,whole grains, vegetables, soy products, and nuts) than the general population (P vegetarians took dietary supplements. 0. 77% of population in Shanghai was vegetarian. The two main reasons for adopting a vegetarian lifestyle were religion and health. The vegetarians tend to have more nutrition knowledge, better attitude and behavior on health. However, most of the vegetarians had not realized the nutrient deficiency risk of vegetarian diets.

  1. Synthesis, structural, and photophysical studies of π-fused acenaphtho[1,2-d]imidazole-based excited-state intramolecular proton transfer molecules

    Science.gov (United States)

    Somasundaram, Sivaraman; Kamaraj, Eswaran; Hwang, Su Jin; Jung, Sooyoung; Choi, Moon Gun; Park, Sanghyuk

    2017-06-01

    Orange-red fluorescent molecules are promising materials for use in a new generation of displays, light sources, and chemosensors because conventional red-emitters have lower fluorescence quantum efficiencies. In this work, a set of orange-emitting fused imidazole series 2-(7-(4-fluorophenyl)-7H-acenaphtho[1,2-d]imidazol-8-yl)phenol (AHPI-F), 2-(7-(4-chlorophenyl)-7H-acenaphtho[1,2-d]imidazol-8-yl)phenol (AHPI-Cl), and 2-(7-(4-bromophenyl)-7H-acenaphtho[1,2-d]imidazol-8-yl)phenol (AHPI-Br) have been synthesized via multicomponent reaction method with high yield. Synthesized molecules were fully characterized by 1H NMR, 13C NMR, GC-Mass, UV-vis. absorption, PL, and TGA-DSC. The compounds AHPI-F, AHPI-Cl, AHPI-Br showed large Stokes' shifted emission due to excited-state intramolecular proton transfer (ESIPT) process, and they effectively formed large single crystals. The crystal structure of each compound was identified by X-ray crystallographic analysis. To elucidate the photophysical properties of the molecule, theoretical calculation were performed by density functional theory (DFT) with B3LYP 6-31G(d,p) basis sets using the identified molecular conformations from X-ray analysis. Calculated electronic properties including HOMO-LUMO levels were compared with the experimental results. As a result of ESIPT process, extended conjugation length through acenaphto[1,2-d]imidazole, and charge transfer characteristics by the introduction of halogen atoms, all of the materials showed orange ESIPT emission with no spatial overlap between absorption (λmax,abs = 325 nm) and emission (λmax,ems = 578 nm).

  2. Autosomal recessive transmission of a rare KRT74 variant causes hair and nail ectodermal dysplasia: allelism with dominant woolly hair/hypotrichosis.

    Directory of Open Access Journals (Sweden)

    Doroteya Raykova

    Full Text Available Pure hair and nail ectodermal dysplasia (PHNED comprises a heterogeneous group of rare heritable disorders characterized by brittle hair, hypotrichosis, onychodystrophy and micronychia. Autosomal recessive (AR PHNED has previously been associated with mutations in either KRT85 or HOXC13 on chromosome 12p11.1-q14.3. We investigated a consanguineous Pakistani family with AR PHNED linked to the keratin gene cluster on 12p11.1 but without detectable mutations in KRT85 and HOXC13. Whole exome sequencing of affected individuals revealed homozygosity for a rare c.821T>C variant (p.Phe274Ser in the KRT74 gene that segregates AR PHNED in the family. The transition alters the highly conserved Phe274 residue in the coil 1B domain required for long-range dimerization of keratins, suggesting that the mutation compromises the stability of intermediate filaments. Immunohistochemical (IHC analyses confirmed a strong keratin-74 expression in the nail matrix, the nail bed and the hyponychium of mouse distal digits, as well as in normal human hair follicles. Furthermore, hair follicles and epidermis of an affected family member stained negative for Keratin-74 suggesting a loss of function mechanism mediated by the Phe274Ser substitution. Our observations show for the first time that homozygosity for a KRT74 missense variant may be associated with AR PHNED. Heterozygous KRT74 mutations have previously been associated with autosomal dominant woolly hair/hypotrichosis simplex (ADWH. Thus, our findings expand the phenotypic spectrum associated with KRT74 mutations and imply that a subtype of AR PHNED is allelic with ADWH.

  3. Splenic autotransplantation and oesophageal transection anastomosis in patients with portal hypertension(26 years clinical observation)

    Institute of Scientific and Technical Information of China (English)

    CHEN Jisheng; HUO Jinshan; ZHANG Hongwei; SHANG Changzhen; CHEN Rufu; ZHANG Jie; Obetien Mapudengo; CHEN Yajin; ZHANG Lei

    2007-01-01

    The surgical treatment methods for cirrhosis patients complicated with portal hypertension are complicated.In this study,we evaluated the effectiveness of a new treatment strategy:splenic auto-transplantation and oesophageal transection anastomosis on 274 patients from three aspects:clinical observation,splenic immunology and portal dynamics.From 1979 to 2005,274 cirrhosis patients with portal hypertension who underwent the new treatment strategy were followed up to observe different clinical indexes,which were then compared with those of the traditional surgery treatment.From 1999 to 2002,a randomized control trial (RCT) was performed on 40 patients to compare their immune function after operation.From 1994 to 2004,another RCT.was carried out on 28 patients to compare the portal dynamics through three-dimensional dynamic contrast enhanced MR angiography (3D DEC MR.A) investigation after operation.Among 274 patients (mean age 41.8 years),the emergency operative mortality (4.4%),selective operative mortality (2.2%),complication rate (17.9%),morbidity of hepatic encephalopathy ( < 1%),bleeding rate of portal hypertension gastritis (PHG) (9.1%),and morbidity of hepatic carcinoma (8%) were similar to those under traditional operation;the spleen immunology function (Tuftsin,IgM)decreased among the groups 2 months after operation.Through 3D DCE MRA,the cross section area,the velocity and volume of blood flow of main portal vein decrease significantly after operation in both groups,the auto transplantation group was significantly lower in velocity and volume of blood flow than in the control group.Splenic auto transplantation and esophageal transection anastomosis are a safe,effective,and reasonable treatment strategy for portal hypertension with varicial bleeding.It can not only correct hypersplenism but also completely stanch blood,and auto transplanted spleen in the retroperitoneal space can preserve immune function and establish abroad collateral circulation.

  4. A 26-year clinical observation of splenic auto-transplantation and oesophageal transection anastomosis: a new treatment strategy in patients with portal hypertension

    Institute of Scientific and Technical Information of China (English)

    ZHANG Lei; CHEN Ji-sheng; HUO Jin-shan; ZHANG Hong-wei; CHEN Ru-fu; ZHANG Jie; Obetien Mapudengo; FANG Tian-lin; CHEN Ya-jin; OU Qing-jia

    2007-01-01

    Background Surgical treatment options for patients with cirrhosis and portal hypertension are complicated. In this study,we evaluated the effectiveness of a new treatment strategy, splenic auto-transplantation and oesophageal transection anastomosis. We report results from clinical observations, splenic immune function and portal dynamics in 274 patients.Methods From 1979 to 2005, 274 cirrhosis patients with portal hypertension underwent the new treatment strategy, and were followed up to compare results with those patients who underwent traditional surgical treatment. From 1999 to 2002,a randomized controlled trial (RCT) was performed on 40 patients to compare their post-operative immune function. From 1994 to 2006, another RCT enrolled 28 patients to compare portal dynamics using three-dimensional dynamic contrast-enhanced magnetic resonance angiography (3D DEC MRA) investigation post operation.Results Among 274 patients (mean age 41.8 years), the emergency operative mortality (4.4%), selective operative mortality (2.2%), complication rate (17.9%), prevalence of hepatic encephalopathy (<1%), rate of portal hypertension gastritis (PHG) bleeding (9.1%), and morbidity of hepatic carcinoma (8%) were similar to those patients undergoing traditional operation; the spleen immunology function (Tuftsin, IgM) decreased in both groups 2 months post operation,but this decrease did not reach statistical significance. Through 3D DCE MRA, the cross sectional area and the velocity and volume of blood flow of the main portal vein decreased significantly after operation in both groups. The velocity and volume of blood flow in the auto-transplantation group was significantly lower than that in the control group.Conclusions Splenic auto-transplantation and esophageal transection anastomosis is a safe, effective, and reasonable treatment strategy for patients with portal hypertension with varicial bleeding. It not only can correct hypersplenism, but may also achieve complete

  5. Pathologic Outcomes of Architectural Distortion on Digital 2D Versus Tomosynthesis Mammography.

    Science.gov (United States)

    Bahl, Manisha; Lamb, Leslie R; Lehman, Constance D

    2017-08-23

    The purpose of this study is to compare the risk of malignancy associated with architectural distortion detected on 2D digital mammography (DM) versus digital breast tomosynthesis (DBT). We performed a retrospective review of architectural distortion cases recommended for biopsy from September 2007 to February 2011, the period before DBT integration (hereafter known as the DM group), and from January 2013 to June 2016, the period after DBT integration (hereafter known as the DBT group). Medical records were reviewed for imaging findings and pathology results. Architectural distortion was more commonly detected in the DBT group than the DM group (0.14% [274/202,438 examinations] vs 0.07% [121/166,661 examinations]; p < 0.001). The positive predictive value of architectural distortion for malignancy was significantly lower in the DBT group than the DM group (50.7% [139/274 cases] vs 73.6% [89/121 cases]; p < 0.001). Radial scar was the most common nonmalignant finding in both groups, but it was more common in the DBT group (33.2% [91/274] vs 11.6% [14/121]; p < 0.001). In the DBT group, architectural distortion without correlative findings on ultrasound was less likely to represent malignancy than was architectural distortion with correlative findings on ultrasound (29.2% [31/106] vs 66.5% [105/158]; p < 0.001). Architectural distortion is more commonly detected on DBT than DM and is less likely to represent malignancy on DBT. Architectural distortion on DBT is less likely to represent malignancy if there is no sonographic correlate; however, biopsy is warranted even in the absence of a sonographic correlate, given the nearly 30% risk of malignancy in this setting.

  6. Presence and molecular characterisation of Giardia and Cryptosporidium in alpacas (Vicugna pacos) from Peru.

    Science.gov (United States)

    Gómez-Couso, Hipólito; Ortega-Mora, Luis M; Aguado-Martínez, Adriana; Rosadio-Alcántara, Raúl; Maturrano-Hernández, Lenin; Luna-Espinoza, Luis; Zanabria-Huisa, Víctor; Pedraza-Díaz, Susana

    2012-07-06

    The presence of Giardia and Cryptosporidium was investigated in 274 faecal samples of alpacas (Vicugna pacos) from 12 herds from Peru by immunofluorescence microscopy and PCR amplification and sequencing of fragments of the ssu-rRNA and β-giardin genes from Giardia spp., as well as the ssu-rRNA gene from Cryptosporidium spp. A total of 137 samples (50.0%) were positive for Giardia spp., and 12 samples (4.4%) for Cryptosporidium spp. In ten samples (3.6%), co-infection by both pathogens was found. Herd prevalence was found to be 91.7% (11/12 herds) for Giardia and 58.3% (7/12 herds) for Cryptosporidium. Regarding the age of the animals, although Giardia was detected in animals as young as 1 week, the prevalence increased with age, reaching 80% by 8 weeks. Similarly, the highest percentage of Cryptosporidium detection (20%) was also found in the 8 week-old group. By PCR, 92 of the 274 analysed samples were positive for Giardia. Sequencing of the amplicons showed the existence of Giardia duodenalis assemblage A in 67 samples; G. duodenalis assemblage E in 24 samples; and inconsistent results between the two molecular markers used in a further sample. Cryptosporidium was only detected by PCR in 3 of the 274 samples; Cryptosporidium parvum was identified in two samples and Cryptosporidium ubiquitum in one sample. This study is the first performing molecular characterisation of both parasites in Peruvian alpacas, and the first report of C. ubiquitum in this host. The identification of G. duodenalis assemblage A, C. parvum and C. ubiquitum, suggests that zoonotic transmission of these enteropathogens between alpacas and humans is possible.

  7. Community-based Disease Management Model for Chronic Heart Failure%慢性心力衰竭社区疾病管理模式探索

    Institute of Scientific and Technical Information of China (English)

    单红; 练宇; 刘振芳; 范文娟; 郭莹; 彭翔; 彭建强; 冯洁; 唐铭翔; 颜素岚; 谢琼; 邹琼超; 傅庆华

    2014-01-01

    Objective To understand the characteristics of people with chronic heart failure in community,based on which to make the suitable community management of the disease,next to discuss whether patients with chronic heart failure can benefit from the community management or not,so as to provides a new way for comprehensive prevention of chronic heart fail-ure. Methods (1) Self-designed questionnaire was used to investigate 288 patients with chronic heart failure in Liufu Street community of Changsha from March to April in 2012 who volunteered to take part in the community management about the charac-teristics of heart failure population. (2) Self-designed systematic management methods of chronic heart failure disease was used to interfere another 200 patients in the community drug treatment from May 2012 to May 2013,health education,lifestyle,self-management,etc. Patients' basic indexes controlling situation,usage rate of heart failure conventional drugs,awareness rate of heart failure knowledge,self-management,MNLF scores,frequency of hospitalization and incidence of cardiovascular events were observed before and after the intervention. Results (1)288 questionnaire were sent out,receiving 279 questionnaires with a recovering rate of 96. 88% and 274 valid questionnaires with an effective rate of 98. 21%. The average age of the patients was(68. 7 ± 10. 6);MNLF score was(22. 13 ± 14. 64);68. 61%(188/274)of the patients had low salt and low fat diets;41. 97%(115/274)measured their blood pressure on a regular basis;the control rate of blood pressure was 35. 40%(97/274);the active follow-up rate was 25. 18%(69/274)and the active accepting health education was 8. 03%(22/274). (2)After intervention,blood pressure control rate and heart rate control rate were higher than before(P﹤0. 05). The differ-ence of blood sugar control rate before and after intervention was not significant(P﹥0. 05). The usage rate of ACEI/ARB andβblockers,the awareness rate of heart failure

  8. Templated Aggregation of TAR DNA-binding Protein of 43 kDa (TDP-43) by Seeding with TDP-43 Peptide Fibrils.

    Science.gov (United States)

    Shimonaka, Shotaro; Nonaka, Takashi; Suzuki, Genjiro; Hisanaga, Shin-Ichi; Hasegawa, Masato

    2016-04-22

    TAR DNA-binding protein of 43 kDa (TDP-43) has been identified as the major component of ubiquitin-positive neuronal and glial inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Aggregation of TDP-43 to amyloid-like fibrils and spreading of the aggregates are suggested to account for the pathogenesis and progression of these diseases. To investigate the molecular mechanisms of TDP-43 aggregation, we attempted to identify the amino acid sequence required for the aggregation. By expressing a series of deletion mutants lacking 20 amino acid residues in the C-terminal region in SH-SY5Y cells, we established that residues 274-313 in the glycine-rich region are essential for aggregation. In vitro aggregation experiments using synthetic peptides of 40 amino acids from this sequence and adjacent regions showed that peptides 274-313 and 314-353 formed amyloid-like fibrils. Transduction of these fibrils induced seed-dependent aggregation of TDP-43 in cells expressing wild-type TDP-43 or TDP-43 lacking nuclear localization signal. These cells showed different phosphorylated C-terminal fragments of TDP-43 and different trypsin-resistant bands. These results suggest that residues 274-353 are responsible for the conversion of TDP-43 to amyloid-like fibrils and that templated aggregation of TDP-43 by seeding with different peptides induces various types of TDP-43 pathologies, i.e. the peptides appear to act like prion strains. © 2016 by The American Society for Biochemistry and Molecular Biology, Inc.

  9. Bioinformatic analysis of computational identified differentially expressed genes in tumor stoma of pregnancy‑associated breast cancer.

    Science.gov (United States)

    Zhou, Qian; Sun, Erhu; Ling, Lijun; Liu, Xiaofeng; Zhang, Min; Yin, Hong; Lu, Cheng

    2017-09-01

    The present study aimed to screen the differentially expressed genes (DEGs) in tumor‑associated stroma of pregnancy‑associated breast cancer (PABC). By analyzing Affymetrix microarray data (GSE31192) from the Gene Expression Omnibus database, DEGs between tumor asso-ciated stromal cells and normal stromal cells in PABC were identified. Gene Ontology (GO) function and pathway enrichment analyses for the DEGs were then performed, followed by construction of a protein‑protein interaction (PPI) network. A total of 94 upregulated and 386 downregulated DEGs were identified between tumor associated stromal cells and normal stromal cells in patients with PABC. The upregulated DEGs were primarily enriched in the cytokine‑cytokine receptor interaction pathway and GO terms associated with the immune response, which included the DEGs of interleukin 18 (IL18) and cluster of differentiation 274 (CD274). The downregulated DEGs were primarily involved in GO terms associated with cell surface receptor linked signal transduction and pathways of focal adhesion and pathways in cancer. In the PPI network, nodes of jun proto‑oncogene (JUN), FBJ murine osteosarcoma viral oncogene homolog (FOS), V‑myc avian myelocytomatosis viral oncogene homolog (MYC), and alpha‑smooth muscle actin (ACTA2) had higher degrees. The hub genes of JUN, FOS, MYC and ACTA2, as well as the DEGs IL18 and CD274 that were associated with the immune response in GO terms may exert important functions in the molecular mechanisms of PABC. These genes may be used as new molecular targets in the treatment of this disease.

  10. Clonal dissemination, emergence of mutator lineages and antibiotic resistance evolution in Pseudomonas aeruginosa cystic fibrosis chronic lung infection.

    Directory of Open Access Journals (Sweden)

    Carla López-Causapé

    Full Text Available Chronic respiratory infection by Pseudomonas aeruginosa is a major cause of mortality in cystic fibrosis (CF. We investigated the interplay between three key microbiological aspects of these infections: the occurrence of transmissible and persistent strains, the emergence of variants with enhanced mutation rates (mutators and the evolution of antibiotic resistance. For this purpose, 10 sequential isolates, covering up to an 8-year period, from each of 10 CF patients were studied. As anticipated, resistance significantly accumulated overtime, and occurred more frequently among mutator variants detected in 6 of the patients. Nevertheless, highest resistance was documented for the nonmutator CF epidemic strain LES-1 (ST-146 detected for the first time in Spain. A correlation between resistance profiles and resistance mechanisms evaluated [efflux pump (mexB, mexD, mexF, and mexY and ampC overexpression and OprD production] was not always obvious and hypersusceptibility to certain antibiotics (such as aztreonam or meropenem was frequently observed. The analysis of whole genome macrorestriction fragments through Pulsed-Field Gel Electrophoresis (PFGE revealed that a single genotype (clone FQSE-A produced persistent infections in 4 of the patients. Multilocus Sequence typing (MLST identified clone FQSE-A as the CF epidemic clone ST-274, but striking discrepancies between PFGE and MLST profiles were evidenced. While PFGE macrorestriction patterns remained stable, a new sequence type (ST-1089 was detected in two of the patients, differing from ST-274 by only two point mutations in two of the genes, each leading to a nonpreviously described allele. Moreover, detailed genetic analyses revealed that the new ST-1089 is a mutS deficient mutator lineage that evolved from the epidemic strain ST-274, acquired specific resistance mechanisms, and underwent further interpatient spread. Thus, presented results provide the first evidence of interpatient dissemination

  11. Cloning, expression, and characterization of a novel xylose reductase from Rhizopus oryzae.

    Science.gov (United States)

    Zhang, Min; Jiang, Shao-tong; Zheng, Zhi; Li, Xing-jiang; Luo, Shui-zhong; Wu, Xue-feng

    2015-07-01

    Rhizopus oryzae is valuable as a producer of organic acids via lignocellulose catalysis. R. oryzae metabolizes xylose, which is one component of lignocellulose hydrolysate. In this study, a novel NADPH-dependent xylose reductase gene from R. oryzae AS 3.819 (Roxr) was cloned and expressed in Pichia pastoris GS115. Homology alignment suggested that the 320-residue protein contained domains and active sites belonging to the aldo/keto reductase family. SDS-PAGE demonstrated that the recombinant xylose reductase has a molecular weight of approximately 37 kDa. The optimal catalytic pH and temperature of the purified recombinant protein were 5.8 and 50 °C, respectively. The recombinant protein was stable from pH 4.4 to 6.5 and at temperatures below 42 °C. The recombinant enzyme has bias for D-xylose and L-arabinose as substrates and NADPH as its coenzyme. Real-time quantitative reverse transcription PCR tests suggested that native Roxr expression is regulated by a carbon catabolite repression mechanism. Site-directed mutagenesis at two possible key sites involved in coenzyme binding, Thr(226)  → Glu(226) and Val(274)  → Asn(274), were performed, respectively. The coenzyme specificity constants of the resulted RoXR(T226E) and RoXR(V274N) for NADH increased 18.2-fold and 2.4-fold, which suggested possibility to improve the NADH preference of this enzyme through genetic modification.

  12. ATRX binds to atypical chromatin domains at the 3' exons of zinc finger genes to preserve H3K9me3 enrichment.

    Science.gov (United States)

    Valle-García, David; Qadeer, Zulekha A; McHugh, Domhnall S; Ghiraldini, Flávia G; Chowdhury, Asif H; Hasson, Dan; Dyer, Michael A; Recillas-Targa, Félix; Bernstein, Emily

    2016-06-02

    ATRX is a SWI/SNF chromatin remodeler proposed to govern genomic stability through the regulation of repetitive sequences, such as rDNA, retrotransposons, and pericentromeric and telomeric repeats. However, few direct ATRX target genes have been identified and high-throughput genomic approaches are currently lacking for ATRX. Here we present a comprehensive ChIP-sequencing study of ATRX in multiple human cell lines, in which we identify the 3' exons of zinc finger genes (ZNFs) as a new class of ATRX targets. These 3' exonic regions encode the zinc finger motifs, which can range from 1-40 copies per ZNF gene and share large stretches of sequence similarity. These regions often contain an atypical chromatin signature: they are transcriptionally active, contain high levels of H3K36me3, and are paradoxically enriched in H3K9me3. We find that these ZNF 3' exons are co-occupied by SETDB1, TRIM28, and ZNF274, which form a complex with ATRX. CRISPR/Cas9-mediated loss-of-function studies demonstrate (i) a reduction of H3K9me3 at the ZNF 3' exons in the absence of ATRX and ZNF274 and, (ii) H3K9me3 levels at atypical chromatin regions are particularly sensitive to ATRX loss compared to other H3K9me3-occupied regions. As a consequence of ATRX or ZNF274 depletion, cells with reduced levels of H3K9me3 show increased levels of DNA damage, suggesting that ATRX binds to the 3' exons of ZNFs to maintain their genomic stability through preservation of H3K9me3.

  13. The Work Unit Information System

    Science.gov (United States)

    1990-03-01

    detl- il 𔃻’ 1hiLS. dIxam.rnt. no.y be- used in conjuctien with tlie video, or !sep1aTate’ly. 114. SUBJECT TERMS 1%. NUMLItH Of 01 AuLAS 12, yi N~I) I T...6145, (202) 274-6817, (AV) 284-6817. 1I 10. WINS AND INPUT WRAP-UP The Army Material Command has implemented its own PC-based work unit input system...extrusion and composite materials . An example of a contract search would be: Find all work units that relate to contract F33615-84-K-2458. An example

  14. Long-Term Prospective Study of 6104 Survivors of Arsenic Poisoning During Infancy Due to Contaminated Milk Powder in 1955

    OpenAIRE

    Tanaka, Hideo; Tsukuma, Hideaki; Oshima, Akira

    2010-01-01

    Background In 1955, an outbreak of arsenic poisoning caused by ingestion of arsenic-contaminated dry milk occurred in western Japan. We assessed the excess mortality among Japanese who were poisoned during this episode as infants. Methods We identified and enrolled 6104 survivors (mean age at enrollment, 27.4 years) who had ingested contaminated milk when they were age 2 years or younger; they were followed until 2006 (mean duration of follow-up, 24.3 years). Death certificates of subjects wh...

  15. Total Solar Eclipse of 17-18 March 1988,

    Science.gov (United States)

    1987-03-17

    05.0 Sapporo , Japan 2 35 29.9 55.5 0.637 46 177 .127 00.0 +37 30.0 Seoul, S. Korea 2 07 03.0 38.2 0.487 46 145 .121 25.6 .31 11.4 Shanghai Obs., P.8...18.2 78.2 0.820 37 87 .106 52.0 +47 54.0 Ulaanbaatac. Mongolia 1 58 04.1 5.3 0.126 27 127 * 79 27.4 +29 21.6 Uttar Pradesh State Obs.. India 1 03 46.6

  16. The sensorimotor system minimizes prediction error for object lifting when the object's weight is uncertain.

    Science.gov (United States)

    Brooks, Jack; Thaler, Anne

    2017-08-01

    A reliable mechanism to predict the heaviness of an object is important for manipulating an object under environmental uncertainty. Recently, Cashaback et al. (Cashaback JGA, McGregor HR, Pun HCH, Buckingham G, Gribble PL. J Neurophysiol 117: 260-274, 2017) showed that for object lifting the sensorimotor system uses a strategy that minimizes prediction error when the object's weight is uncertain. Previous research demonstrates that visually guided reaching is similarly optimized. Although this suggests a unified strategy of the sensorimotor system for object manipulation, the selected strategy appears to be task dependent and subject to change in response to the degree of environmental uncertainty. Copyright © 2017 the American Physiological Society.

  17. A population-based study of morbidity and mortality in mannose-binding lectin deficiency

    DEFF Research Database (Denmark)

    Dahl, Morten; Tybjaerg-Hansen, Anne; Schnohr, Peter

    2004-01-01

    genotyped 9,245 individuals from the adult Danish population for three MBL deficiency alleles, B, C, and D, as opposed to the normal noncarrier A allele. Hospitalization incidence per 10,000 person. yr was 644 in noncarriers compared with 631 in heterozygotes (log-rank: P = 0.39) and 658 in deficiency...... homozygotes (P = 0.53). Death incidence per 10,000 person. yr was 235 in noncarriers compared with 244 in heterozygotes (P = 0.44) and 274 in deficiency homozygotes (P = 0.12). After stratification by specific cause of hospitalization or death, only hospitalization from cardiovascular disorders was increased...

  18. A comparison of the effect of epidermal growth factor, platelet-derived growth factor, and fibroblast growth factor on rat periodontal ligament fibroblast-like cells' DNA synthesis and morphology

    DEFF Research Database (Denmark)

    Blom, S; Holmstrup, P; Dabelsteen, Erik

    1994-01-01

    An enhanced formation of bone, dentin, and collagen fibers in periodontal wounds after application of polypeptide growth factors has recently been reported. However, the complex environment in vivo makes it impossible to determine the specific effects of growth factors on various cells involved...... nuclei. Incorporation of [3H]-thymidine was increased in a dose-dependent manner by all growth factors. Maximal effect on the DNA synthesis was: rEGF, 131%; nPDGF, 274%; and nFGF, 182%.(ABSTRACT TRUNCATED AT 250 WORDS)...

  19. [Vertical dimension in the OSAHS in adults: an example of functional alteration].

    Science.gov (United States)

    Raskin, S; Limme, M

    2003-09-01

    Obstructive sleep apnea and hypoapnea syndrome (OSAHS) is important to orthodontists for several reasons. The authors, after defining OSAHS and describing it briefly, review the literature dealing with the cranio-facial morphology of apnea patients. They report the results of their cephalometric study, which is based on an architectural analysis of 274 patients. Their facial characteristics, especially vertical dimension, are consistent with those displayed by mouth breathing children. Changes in respiratory functioning modify the mechanical behavior and the structures of the upper airways. Osseous tissues also show signs caused by these changes. The authors propose an etiopathogenic model.

  20. Dicty_cDB: Contig-U14088-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available 0 Length of query: 109 Length of database: 95,242,211,685 Length adjustment: 22 Effective... length of query: 87 Effective length of database: 93,199,600,587 Effective search space: 8108365251069 Effective...er of HSP's successfully gapped: 0 Length of query: 36 Length of database: 1,051,180,864 Length adjustment: 10 Effective... length of query: 26 Effective length of database: 1,018,815,274 Effective... search space: 26489197124 Effective search space used: 26489197124 Neighboring words threshold: 12 Win