Sample records for bohrium 274

  1. 33 CFR 274.5 - Certification. (United States)


    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Certification. 274.5 Section 274... PEST CONTROL PROGRAM FOR CIVIL WORKS PROJECTS Project Operation § 274.5 Certification. Under the... certification of pesticide applicators through its development of a single Government Agency Plan (GAP)....

  2. 7 CFR 274.7 - Coupon management. (United States)


    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Coupon management. 274.7 Section 274.7 Agriculture... FOOD STAMP AND FOOD DISTRIBUTION PROGRAM ISSUANCE AND USE OF COUPONS § 274.7 Coupon management. (a) Coupon inventory management. State agencies shall establish coupon inventory management systems...

  3. 33 CFR 274.4 - Pesticide management. (United States)


    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Pesticide management. 274.4... DEFENSE PEST CONTROL PROGRAM FOR CIVIL WORKS PROJECTS Project Operation § 274.4 Pesticide management. (a... control management personnel prior to advertisement of the contract and procurement of services....

  4. 38 CFR 17.274 - Cost sharing. (United States)


    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2010-07-01 2010-07-01 false Cost sharing. 17.274 Section 17.274 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS MEDICAL Civilian... the beneficiary cost share. (b) In addition to the beneficiary cost share, an annual (calendar...

  5. 7 CFR 274.3 - Issuance systems. (United States)


    ... accesses a master issuance file at the time that benefits are issued to households. This system shall use manual card access or an automated access to the master issuance file. Systems of this type include the... 7 Agriculture 4 2010-01-01 2010-01-01 false Issuance systems. 274.3 Section 274.3...

  6. Dicty_cDB: CHR274 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available CH (Link to library) CHR274 (Link to dictyBase) - G23014 DDB0205932 Contig-U11587-1 | Contig-U13150-1 CHR...274P (Link to Original site) CHR274F 618 CHR274Z 715 CHR274P 1313 - - Show CHR274 Libr...ary CH (Link to library) Clone ID CHR274 (Link to dictyBase) Atlas ID - NBRP ID G23014 dictyBase ID Representative seq. ID CHR274P (Link to Original site) ...Representative DNA sequence >CHR274 (CHR274Q) /CSM/CH/CHR2-D/CHR274Q.Seq.d/ GTAATAATAATTTTAAAAAATCAAATAGTAAT

  7. Dicty_cDB: SSG274 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available SS (Link to library) SSG274 (Link to dictyBase) - G01218 DDB0190845 Contig-U11005-1 SSG...274P (Link to Original site) SSG274F 390 SSG274Z 515 SSG274P 905 - - Show SSG274 Library SS (Link to library) Clone ID SSG...ontig-U11005-1 Original site URL Representative seq. ID SSG274P (Link to Original site) Representative DNA sequence >SSG274 (SSG274Q) /CSM/SS/SSG...2-D/SSG274Q.Seq.d/ AAATAATAATAATAATAATAATATTGAAAATAATAAAAATAATAAAAATAATAATATTTA ATAATAAA

  8. Dicty_cDB: SLE274 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available ar 16.0 %: mitochondrial 8.0 %: vesicles of secretory system 4.0 %: vacuolar >> prediction for SLE...SL (Link to library) SLE274 (Link to dictyBase) - - - Contig-U12305-1 SLE274P (Link to Original site) SLE...274F 703 SLE274Z 333 SLE274P 1036 - - Show SLE274 Library SL (Link to library) Clone ID SLE...e URL Representative seq. ID SLE...274P (Link to Original site) Representative DNA sequence >SLE274 (SLE274Q) /CSM/SL/SLE2-D/SLE

  9. 8 CFR 274a.3 - Continuing employment of unauthorized aliens. (United States)


    ... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Continuing employment of unauthorized aliens. 274a.3 Section 274a.3 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS CONTROL OF EMPLOYMENT OF ALIENS Employer Requirements § 274a.3 Continuing employment...

  10. 12 CFR 27.4 - Inquiry/Application Log. (United States)


    ... of the Federal Reserve Board, 12 CFR part 203) indicates a pattern of significant variation in the... 12 Banks and Banking 1 2010-01-01 2010-01-01 false Inquiry/Application Log. 27.4 Section 27.4... SYSTEM § 27.4 Inquiry/Application Log. (a) The Comptroller, among other things, may require a bank...

  11. Properties of an $\\alpha$ particle in a Bohrium $270$ Nucleus under the Generalized Symmetric Woods-Saxon Potential

    CERN Document Server

    Lütfüoğlu, B C


    The energy eigenvalues and the wave functions of an $\\alpha$ particle in a Bohrium $270$ nucleus were calculated by solving Schr\\"odinger equation for Generalized Symmetric Woods-Saxon potential. Using the energy spectrum by excluding and including the quasi-bound eigenvalues, entropy, internal energy, Helmholtz energy, and specific heat, as functions of reduced temperature were calculated. Stability and emission characteristics are interpreted in terms of the wave and thermodynamic functions. The kinetic energy of a decayed $\\alpha$ particle was calculated using the quasi-bound states, which is found close to the experimental value.

  12. 26 CFR 1.274-5A - Substantiation requirements. (United States)


    ... be required. For example, in the case of a salesman calling on customers on an established sales... implement the provisions of section 274 and the regulations thereunder by personal interview or...

  13. Test report - 241-AN-274 Caustic Pump Control Building

    Energy Technology Data Exchange (ETDEWEB)

    Paintner, G.P.


    This Acceptance Test Report documents the test results of test procedure WHC-SD-WM-ATP-135 `Acceptance Test Procedure for the 241-AN- 274 Caustic Pump Control Building.` The objective of the test was to verify that the 241-AN-274 Caustic Pump Control Building functions properly based on design specifications per applicable H-2-85573 drawings and associated ECN`s. The objective of the test was met.

  14. 40 CFR 761.274 - Reporting PCB concentrations in samples. (United States)


    ... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Reporting PCB concentrations in... COMMERCE, AND USE PROHIBITIONS Cleanup Site Characterization Sampling for PCB Remediation Waste in Accordance with § 761.61(a)(2) § 761.274 Reporting PCB concentrations in samples. (a) Report all...

  15. 8 CFR 274a.12 - Classes of aliens authorized to accept employment. (United States)


    ... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Classes of aliens authorized to accept employment. 274a.12 Section 274a.12 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS CONTROL OF EMPLOYMENT OF ALIENS Employment Authorization § 274a.12 Classes of aliens authorized...

  16. 48 CFR 236.274 - Restriction on acquisition of steel for use in military construction projects. (United States)


    ... of steel for use in military construction projects. 236.274 Section 236.274 Federal Acquisition....274 Restriction on acquisition of steel for use in military construction projects. In accordance with..., Division E), do not acquire, or allow a contractor to acquire, steel for any construction project...

  17. The skills for genesis2000 reading 274D%浅谈Genesis读取274D格式技巧

    Institute of Scientific and Technical Information of China (English)

    王忱; 李加余; 黄慧


    Genesis 2000是处理PCB线路图形达到现场生产能力并满足客户要求的一种高级计算机辅助制造软件,CAM制作料号前必须将客户提供之CAD/CAM档案转换成厂内可使用之文件格式。 Genesis 2000读取客户资料的正确性,直接会影响每款产品的正确性,文章主要探讨genesis2000读取274D格式技巧。%Genesis 2000 is an advanced computer-aided manufacturing software processing PCB line and graph to reach the production capacity and meet customer requirements. Before the materials process, CAD/CAMfiles must be provided and changed into a plant suitable format which can be used. The correctness of the Genesis 2000 reading customer data directly affects the accuracy of each product. So this paper mainly discusses genesis2000 reading skills of 274D.

  18. 40 CFR 421.274 - Standards of performance for new sources. (United States)


    ... 40 Protection of Environment 28 2010-07-01 2010-07-01 true Standards of performance for new sources. 421.274 Section 421.274 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS NONFERROUS METALS MANUFACTURING POINT SOURCE CATEGORY Primary Rare...

  19. Orientational Phase Transition Around 274 K in C60 Single Crystal

    Institute of Scientific and Technical Information of China (English)

    徐亚伯; 何丕模; 杨宏顺; 郑萍; 余朝文; 陈兆甲; 张宣嘉; 李文铸


    The electrical conductivity of a C60 single crystal around 274 K and the specific heat of C60 crystals from 150 to 340 K have been measured.The delta-like specific heat peak at about 251 K related to the first-order phase transition has been reported.The activation energy change around 274 K and the lambda-like specific heat peak beginning at 270 K and ending at 310 K show that there is an orientational phase transition in fcc C60 crystals above 251 K.By taking the symmetry into consideration and further analyzing lambda-like specific heat peak and the activation energy change around 274 K,the conclusion has been reached that this new phase transition is an orientational structure transition from the merohedral twinning fcc to the orientationally disordered fcc.The temperature of free rotation of C60 molecules is about 281 K.

  20. Complete Genome Sequence of Mycoplasma yeatsii Strain GM274B (ATCC 43094). (United States)

    Calcutt, Michael J; Kent, Bethany N; Foecking, Mark F


    Mycoplasma yeatsii is a goat mycoplasma species that, although an obligate parasite, accommodates this lifestyle as an inapparent commensalist. High-frequency transformation has also been reported for this species. The complete 895,051-bp genome sequence of strain GM274B has been determined, enabling an analysis of the features of this potential cloning host.

  1. 48 CFR 211.274-5 - Policy for assignment of Government-assigned serial numbers. (United States)


    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Policy for assignment of... DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE ACQUISITION PLANNING DESCRIBING AGENCY NEEDS Using and Maintaining Requirements Documents 211.274-5 Policy for assignment of...

  2. 40 CFR 81.274 - Mountain Counties Intrastate Air Quality Control Region. (United States)


    ... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Mountain Counties Intrastate Air... Air Quality Control Regions § 81.274 Mountain Counties Intrastate Air Quality Control Region. The Mountain Counties Intrastate Air Quality Control Region consists of the territorial area encompassed by...

  3. 33 CFR Appendix A to Part 274 - Preventive Safety Measures in Handling of Pesticides (United States)


    ... protective clothing are rubber aprons, coveralls, chemical splash goggles, safety shoes, and hard hats. A... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Preventive Safety Measures in... Appendix A to Part 274—Preventive Safety Measures in Handling of Pesticides 1. Follow the label on...

  4. 20 CFR 667.274 - What health and safety standards apply to the working conditions of participants in activities... (United States)


    ... working conditions of participants in activities under title I of WIA? 667.274 Section 667.274 Employees... and safety standards apply to the working conditions of participants in activities under title I of... working conditions of employees are equally applicable to working conditions of participants engaged...

  5. 17 CFR 274.11b - Form N-3, registration statement of separate accounts organized as management investment companies. (United States)


    ... statement of separate accounts organized as management investment companies. 274.11b Section 274.11b... accounts organized as management investment companies. Form N-3 shall be used as the registration statement... offer variable annuity contracts to register as management investment companies. This form shall also...

  6. Looking into the Theory of Pulsar Accretion: Cen X-3 and XTE J1946+274

    CERN Document Server

    Marcu, Diana M; Gottlieb, Amy M; Wolff, Michael T; Becker, Peter A; Wilms, Joern; Ferrigno, Carlo; Wood, Kent S


    This is an overview of pulsar accretion modeling. The physics of pulsar accretion, i.e., the process of plasma flow onto the neutron star surface, can be constrained from the spectral properties of the X-ray source. We discuss a new implementation of the physical continuum model developed by Becker and Wolff (2007, ApJ 654, 435). The model incorporates Comptonized blackbody, bremsstrahlung, and cyclotron emission. We discuss preliminary results of applying the new tool to the test cases of Suzaku data of Cen X-3 and XTE J1946+274. Cen X-3 is a persistent accreting pulsar with an O-star companion observed during a bright period. XTE J1946+274 is a transient accreting pulsar with a Be companion observed during a dim period. Both sources show spectra that are well described with an empirical Fermi Dirac cutoff power law model. We extend the spectral analysis by making the first steps towards a physical description of Cen X-3 and XTE J1946+274.


    Institute of Scientific and Technical Information of China (English)

    卢和丽; 袁也丰; 万爱兰; 万福生; 周小军; 章洁


    [目的]探讨江西地区汉族人群微卫星D6S274等位基因多态性与精神分裂症关系.[方法]提取江西地区汉族174例精神分裂症患者及174例健康体检者全血DNA并使用PE9600型PCR扩增仪对其进行扩增,所得PCR产物用ABI3730型基因分析仪自动进行电泳分离和基因检测.[结果]①正常人D6S274基因型频率符合Hardy-Wein-berg平衡定律(x2=39.81,P>0.05);②精神分裂症组D65274位点的172bp等位基因检出率为11.78%,正常对照组的检出率为4.60%,两者差异有统计学意义(x2=11.94,P<0.01);该位点其他各等位基因检出率差异无统计学意义(P>0.05).[结论]6号染色体短臂D6S274附近可能存在精神分裂症的易感基因.%[Objective] To explore association between microsatellite D6S274 polymorphism and schizophrenia. [Methods] DNA samples were collected from patients with schizophrenia (n = 174) and random population (re = 174) in Jiangxi Province. The microsatellite D6S274 were determined with the polymerase chain reaction. [Results] (D The distribution of the allele frequencies in D6S274 loci conformed to Hardy Weinberg equilibrium in the control groups (^ = 39.81, P > 0.05). ② The gene frequency of the allele 172 bp of D6S274 in schizophrenia group was higher than that in control group ( 11.78% vs4.60%, x2 = 11.94, P< 0.01). The frequencies of other alleles did not differ between the schizophrenia and controls. [ConClusion] D6S274 loci in the chromosome 6 may be associated withschizophienia. Gene associated with susceptibility to schizophrenia may exist in the microsatellite marker regions D6S274 of the chromosome 6p.

  8. 274例非小细胞肺癌临床特点分析%Clinical features with non- small- cell lung cancer: An analysis of 274 patients

    Institute of Scientific and Technical Information of China (English)

    陈衍; 韩晟; 薛妍; 刘文超


    目的 了解我国非小细胞肺癌(NSCLC)患者流行病学特点,为临床NSCLC的防治提供参考数据.方法 对某医科大学附属医院肿瘤科组织学确诊的274例NSCLC患者临床特点及其相关因素进行回顾性研究,并分析影响临床分期和病理的独立风险因子.结果 男女比例为1.88∶1.腺癌和鳞癌约占总样本的90%,晚期患者占67.88%.47.45%有吸烟史,约28.83%来自农村.女性、农村患者发病年龄明显低于男性及城市患者.性别、病理类型及手术史是影响临床分期的独立风险因素.女性、腺癌及未进行手术的患者,晚期的比例更高.性别、年龄及吸烟状态均为影响病理的独立风险因素.男性、≤60岁以及吸烟患者更易患鳞癌.无论吸烟与否,男性较女性更易患鳞癌.即使排除吸烟因素,女性也较男性更易患腺癌.结论 NSCLC的发病特点发生变化,应加强对女性、农村人群及中青年的肺癌普查,提高早期NSCLC的筛查率.%Objective To investigate the clinical features of patients with non- small - cell lung cancer (NSCLC) in China in order to provide clinical reference data for further prevention and treatment of NSCLC. Methods The clinical features of 274 cases of NSCLC histologically diagnosed in a university hospital were retrospectively analyzed. The independent influencing factors related to stage and pathology with Cox's regression analysis were studied. Results The male to female ratio was 1.88:1. Squamous cell carcinoma and adenocarcinoma accounted for neatly 90 % in the total sample. Patients were diagnosed with advanced stage (Ⅲ B - Ⅳ) accounted for 67.88 % . Patients with smoking habits accounted for 47.45 % and 28.83 % of them lived in ruraLareas. Multiple regression analysis showed that gender, pathology and surgery were the independent variables influencing clinical stage. Female who had adenocarcinoma and received no surgery had higher incidence of caner in their late

  9. 8 CFR 274a.7 - Pre-enactment provisions for employees hired prior to November 7, 1986 or in the CNMI prior to... (United States)


    ... 8 CFR 274a.2(b)(1)(viii)), except those individuals described in 8 CFR 274a.2(b)(1)(viii)(A)(7)(iii... CNMI prior to the transition program effective date as defined in 8 CFR 1.1. (b) For purposes of this..., situations in which an employee is subject to seasonal employment; or (3) Is excluded or deported from...

  10. Culture conditions of Roseobacter strain 27-4 affect its attachment and biofilm formation as quantified by real-time PCR

    DEFF Research Database (Denmark)

    Bruhn, Jesper Bartholin; Haagensen, Janus Anders Juul; Bagge-Ravn, D.;


    The fish probiotic bacterium Roseobacter strain 27-4 grows only as rosettes and produces its antibacterial compound under static growth conditions. It forms three-dimensional biofilms when precultured under static conditions. We quantified attachment of Roseobacter strain 27-4 using a direct real...

  11. Multi-scalar influences on mortality change over time in 274 European cities. (United States)

    Richardson, Elizabeth A; Moon, Graham; Pearce, Jamie; Shortt, Niamh K; Mitchell, Richard


    Understanding determinants of urban health is of growing importance. Factors at multiple scales intertwine to influence health in cities but, with the growing autonomy of some cities from their countries, city population health may be becoming more a matter for city-level rather than national-level policy and action. We assess the importance of city, country, and macroregional (Western and East-Central Europe) scales to mortality change over time for 274 cities (population 80 million) from 27 European countries. We then investigate whether mortality changes over time are related to changes in city-level affluence. Using Urban Audit data, all-age all-cause standardised mortality ratios (SMRs) for males and females were calculated at three time points (wave one 1999-2002, wave two 2003-2006, and wave three 2007-2009) for each city. Multilevel regression was used to model the SMRs as a function of survey wave and city region gross domestic product (GDP) per 1000 capita. SMRs declined over time and the substantial East-West gap narrowed slightly. Variation at macroregion and country scales characterised SMRs for women in Western and East-Central European cities, and SMRs for men in East-Central European cities. Between-city variation was evident for male SMRs in Western Europe. Changes in city-region GDP per capita were not associated with changes in mortality over the study period. Our results show how geographical scales differentially impact urban mortality. We conclude that changes in urban health should be seen in both city and wider national and macroregional contexts.

  12. Genome Sequencing and Comparative Analysis of the Biocontrol Agent Trichoderma harzianum sensu stricto TR274

    Energy Technology Data Exchange (ETDEWEB)

    Steindorff, Andrei S.; Noronha, Elilane F.; Ulhoa, Cirano J.; Kuo, Alan; Salamov, Asaf A.; Haridas, Sajeet; Riley, Robert W.; Druzhinina, Irina S.; Kubicek, Christian P.; Grigoriev, Igor V.


    Biological control is a complex process which requires many mechanisms and a high diversity of biochemical pathways. The species of Trichoderma harzianum are well known for their biocontrol activity against many plant pathogens. To gain new insights into the biocontrol mechanism used by T. harzianum, we sequenced the isolate TR274 genome using Illumina. The assembly was performed using AllPaths-LG with a maximum coverage of 100x. The assembly resulted in 2282 contigs with a N50 of 37033bp. The genome size generated was 40.8 Mb and the GC content was 47.7%, similar to other Trichoderma genomes. Using the JGI Annotation Pipeline we predicted 13,932 genes with a high transcriptome support. CEGMA tests suggested 100% genome completeness and 97.9% of RNA-SEQ reads were mapped to the genome. The phylogenetic comparison using orthologous proteins with all Trichoderma genomes sequenced at JGI, corroborates the Trichoderma (T. asperellum and T. atroviride), Longibrachiatum (T. reesei and T. longibrachiatum) and Pachibasium (T. harzianum and T. virens) section division described previously. The comparison between two Trichoderma harzianum species suggests a high genome similarity but some strain-specific expansions. Analyses of the secondary metabolites, CAZymes, transporters, proteases, transcription factors were performed. The Pachybasium section expanded virtually all categories analyzed compared with the other sections, specially Longibrachiatum section, that shows a clear contraction. These results suggests that these proteins families have an important role in their respective phenotypes. Future analysis will improve the understanding of this complex genus and give some insights about its lifestyle and the interactions with the environment.

  13. B7-H1 (PD-L1, CD274) suppresses host immunity in T-cell lymphoproliferative disorders


    Wilcox, Ryan A.; Feldman, Andrew L.; Wada, David A.; Yang, Zhi-Zhang; Comfere, Nneka I.; Dong, Haidong; Kwon, Eugene D.; Novak, Anne J.; Markovic, Svetomir N.; Mark R Pittelkow; Witzig, Thomas E.; Ansell, Stephen M.


    Stromal elements present within the tumor microenvironment may suppress host immunity and promote the growth of malignant lymphocytes in B cell–derived non-Hodgkin lymphoma (NHL). In contrast, little is known about the microenvironment's role in T cell–derived NHL. B7-H1 (PD-L1, CD274), a member of the B7 family of costimulatory/coinhibitory ligands expressed by both malignant cells and stromal cells within the tumor microenvironment, has emerged as an important immune modulator capable of su...

  14. The Candidate Cluster and Protocluster Catalog (CCPC) of Spectroscopically Identified Structures Spanning 2.74 < z < 3.71 (United States)

    Franck, J. R.; McGaugh, S. S.


    We developed a search methodology to identify galaxy protoclusters at z\\gt 2.74 and implemented it on a sample of ˜14,000 galaxies with previously measured redshifts. The results of this search are recorded in the Candidate Cluster and Protocluster Catalog (CCPC). The catalog contains 12 clusters that are highly significant overdensities ({δ }{gal}\\gt 7), 6 of which were previously known. We also identify another 31 candidate protoclusters (including four previously identified structures) of lower overdensities. CCPC systems vary over a wide range of physical sizes and shapes, from small, compact groups to large, extended, and filamentary collections of galaxies. This variety persists in the range from z = 3.71 to z = 2.74. These structures exist as galaxy overdensities ({δ }{gal}) with a mean value of 2, similar to the values found for other protoclusters in the literature. The median number of galaxies for CCPC systems is 11. Virial mass estimates are large for these redshifts, with 13 cases apparently having M\\gt {10}15 {M}⊙ . If these systems are virialized, such masses would pose a challenge to ΛCDM.

  15. The candidate cluster and protocluster catalog (CCPC) of spectroscopically identified structures spanning $2.74 < z < 3.71$

    CERN Document Server

    Franck, J R


    We have developed a search methodology to identify galaxy protoclusters at $z>2.74$, and implemented it on a sample of $\\sim$14,000 galaxies with previously measured redshifts. The results of this search are recorded in the Candidate Cluster and Protocluster Catalog (CCPC). The catalog contains 12 clusters that are highly significant overdensities ($\\delta_{gal}>7$), 6 of which are previously known. We also identify another 31 candidate protoclusters (including 4 previously identified structures) of lower overdensity. CCPC systems vary over a wide range of physical sizes and shapes, from small, compact groups to large, extended, and filamentary collections of galaxies. This variety persists over the range from $z=3.71$ to $z=2.74$. These structures exist as galaxy overdensities ($\\delta_{gal}$) with a mean value of 2, similar to the values found for other protoclusters in the literature. The median number of galaxies for CCPC systems is 11. Virial mass estimates are large for these redshifts, with thirteen ca...

  16. Core drilling of hydco drillholes ONK-PP262 and ONK-PP274 in ONKALO at Olkiluoto 2010

    Energy Technology Data Exchange (ETDEWEB)

    Toropainen, V. [Suomen Malmi Oy, Espoo (Finland)


    Suomen Malmi Oy (Smoy) core drilled two drillholes for HYDCO-program in ONKALO at Eurajoki, Olkiluoto in 2010. The drillhole ONK-PP262 was drilled in May 2010 and the drillhole ONK-PP274 in December 2010. The lengths of the drillholes are 25.02 and 23.88 m respectively. The drillholes are 75.7 mm by diameter. The drillholes were drilled in the investigation niche 4 at the access tunnel chainage 3747. The hydraulic DE 130 drilling rig was used. The drilling water was taken from the ONKALO drilling water pipeline and premixed sodium fluorescein was used as a label agent in the drilling water. The drillholes were measured with EMS deviation survey tool. In addition to drilling the drillcores were logged and reported by geologist. Geological logging included the following parameters: lithology, foliation, fracture parameters, fractured zones, core loss, weathering, fracture frequency, RQD and rock quality. The main rock types in the drillholes are veined gneiss and pegmatitic granite. The average fracture frequencies in both drill cores are 1.4 pcs/m. The average RQD values in the drillcores are 97.2 % (ONK-PP262) and 98.6 % (ONK-PP274). (orig.)

  17. Detection of a large Be circumstellar disk during X-ray quiescence of XTE J1946+274

    CERN Document Server

    Arabaci, M Ozbey; Gutierrez-Soto, J; Zurita, C; Nespoli, E; Suso, J; Kiaeerad, F; Garcia-Rojas, J; Kiziloglu, U


    We present a multiwavelength study of the Be/X-ray binary system XTE J1946+274 with the main goal of better characterizing its behavior during X-ray quiescence. We aim to shed light on the mechanism which triggers the X-ray activity for this source. XTE J1946+274 was observed by Chandra-ACIS during quiescence in 2013 March 12. In addition, this source has been monitored from the ground-based astronomical observatories of El Teide (Tenerife, Spain), Roque de los Muchachos (La Palma, Spain) and Sierra Nevada (Granada, Spain) since 2011 September, and from the TUBITAK National Observatory (Antalya, Turkey) since 2005 April. We have performed spectral and photometric temporal analyses in order to investigate the quiescent state and transient behavior of this binary system. In 2006, a long mass ejection event took place from the Be star, lasting for about seven years. We also found that a large Be circumstellar disk was present during quiescence, although major X-ray activity was not observed. We made an attempt t...

  18. 274例梗阻性无精子症经闭合式穿刺取精行ICSI治疗的临床分析%Analysis Clinical Treatment of 274 Cases With Obstructive Azoospermatism Close Needle Aspiration of ICSI

    Institute of Scientific and Technical Information of China (English)

    刘东方; 曲文玉; 董树林


    目的:探讨梗阻性无精子症经闭合式穿刺取精行ICSI治疗的临床效果。方法选取我院行外科闭合式穿刺取精术274例,A组睾丸穿刺取精164例,B组附睾穿刺取精110例,对上述病例的临床资料进行回顾性分析。结果睾丸体积正常的取精成功率高于睾丸体积偏小者, P<0.05,差异具有统计学意义。血清促卵泡刺激素(FSH)水平正常的取精成功率高于FSH增高者,P<0.05,差异具有统计学意义。对比睾丸穿刺组与附睾穿刺组比较术后并发症发生率和术后恢复时间,P<0.05,差异具有统计学意义。结论睾丸穿刺取精术操作简单创伤较小,术后并发症轻,感染、水肿及出血率均低于附睾穿刺取精,且术后恢复时间短。%Objective To explore the clinical effect on 274 cases with obstructive azoospermatism close needle aspiration of ICSI. Methods Selected 274 cases with surgical closure type piercing fine extraction in our hospital, 164 cases of group A piercing testicular, group B epididymis puncture in 110 cases, retrospectively analyzed the clinical data of the above cases. Results The volume normal testicular sperm extraction for managing the success rate was higher than testicular volume by outsiders, P<0.05, had difference statistically signiifcance. Serum cu follicle-stimulating hormone (FSH) levels were normal for ifne success rate increased higher than that of FSH, P<0.05, had difference statistically signiifcance. While testicular biopsy and epididymis puncture group less postoperative complications and postoperative recovery time, P<0.05, had difference statistically signiifcance. Conclusion Puncture testicular sperm extraction for managing the operation is simple and less trauma, postoperative complications, infection, edema and hemorrhage rate were lower than that of epididymis puncture in essence, and postoperative recovery time is short.

  19. Role of the conserved arginine 274 and histidine 224 and 228 residues in the NuoCD subunit of complex I from Escherichia coli. (United States)

    Belevich, Galina; Euro, Liliya; Wikström, Mårten; Verkhovskaya, Marina


    The conserved arginine 274 and histidine 224 and 228 residues in subunit NuoCD of complex I from Escherichia coli were substituted for alanine. The wild-type and mutated NuoCD subunit was expressed on a plasmid in an E. coli strain bearing a nuoCD deletion. Complex I was fully expressed in the H224A and H228A mutants, whereas the R274A mutation yielded approximately 50% expression. Ubiquinone reductase activity of complex I was studied in membranes and with purified enzyme and was 50% and 30% of the wild-type activity in the H224A and H228A mutants, respectively. The activity of R274A was less than 5% of the wild type in membranes but 20% in purified complex I. Rolliniastatin inhibited quinone reductase activity in the mutants with similar affinity as in the wild type, indicating that the quinone-binding site was not significantly altered by the mutations. Ubiquinone-dependent superoxide production by complex I was similar to the wild type in the R274A mutant but slightly higher in the H224A and H228A mutants. The EPR spectra of purified complex I from the H224A and H228A mutants did not differ from the wild type. In contrast, the signals of the N2 cluster and another fast-relaxing [4Fe-4S] cluster, tentatively assigned as N6b, were drastically decreased in the NADH-reduced R274A mutant enzyme but reappeared on further reduction with dithionite. These findings show that the redox potential of the N2 and N6b centers is shifted to more negative values by the R274A mutation. Purified complex I was reconstituted into liposomes, and electric potential was generated across the membrane upon NADH addition in all three mutant enzymes, suggesting that none of the mutations directly affect the proton-pumping machinery.

  20. Geophysical logging and imaging of shallow drillholes ONK-PP262 and ONK-274 at Olkiluoto in 2010

    Energy Technology Data Exchange (ETDEWEB)

    Tarvainen, A.-M. [Suomen Malmi Oy, Espoo (Finland)


    Suomen Malmi Oy conducted geophysical drillhole logging as well as optical and acoustic imaging of shallow drillholes ONK-PP262 and ONK-PP274 at ONKALO in the investigation niche ONK-TKU-4 (Hydco) in May and in December 2010. The survey is a part of Posiva Oy's detailed investigation program for the final disposal of spent nuclear fuel. The assignment included the field work and data processing. The report describes field operation, equipment as well as processing procedures and shows the obtained results and an analysis of their quality in the appendices. The raw and processed data are delivered digitally in WellCAD, PDF and Excel format. (orig.)

  1. The Real Time Mixing Module Design for HDTV Data of SMPTE 274M and PC Video Data

    Institute of Scientific and Technical Information of China (English)

    魏江力; 赵保军; 韩月秋


    A real time mixing module for high definition television (HDTV) data of SMPTE 274M and PC video data is designed. The hardware implementation, algorithm and simulation of the mixing module are given. In order to improve the capability of data processing, an anti-fuse FPGA chip and a mechanism of pipelining and modularization are adopted. With 6 parallel LUTs and a fast algorithm, it can mix 4∶2∶2 component signals in luminance and chrominance space respectively in real time. According to the simulation, the module has the ability to mix the uncompressed HDTV data with PC video data in real time, which can not be fulfilled by current ASIC chips. Furthermore, it can be extended to multi-stage mixing with the thoughts implied by the design. The mixing module can be widely used in HDTV production systems.

  2. Thromboembolic risk in 16 274 atrial fibrillation patients undergoing direct current cardioversion with and without oral anticoagulant therapy

    DEFF Research Database (Denmark)

    Hansen, Morten Lock; Jepsen, Rikke Malene H G; Olesen, Jonas Bjerring;


    AIMS: To study the risk of thromboembolism in a nationwide cohort of atrial fibrillation patients undergoing direct current (DC) cardioversion with or without oral anticoagulant coverage. METHODS AND RESULTS: A retrospective study of 16 274 patients in Denmark discharged from hospital after a first......-time DC cardioversion for atrial fibrillation between 2000 and 2008. Use of oral anticoagulant therapy within 90 days prior and 360 days after DC cardioversion was obtained from the Danish Register of Medicinal Product Statistics. The risk of thromboembolism was estimated by calculating incidence rates...... and by multivariable adjusted Cox proportional-hazard models. During the initial 30 days following discharge, the thromboembolic incidence rate was 10.33 per 100 patient-years for the no prior oral anticoagulant therapy group [n = 5084 (31.2%)], as compared with 4.00 per 100 patient-years for the prior oral...

  3. 50 CFR 660.393 - Latitude/longitude coordinates defining the 100 fm (183 m) through 150 fm (274 m) depth contours. (United States)


    ... 50 Wildlife and Fisheries 9 2010-10-01 2010-10-01 false Latitude/longitude coordinates defining... Latitude/longitude coordinates defining the 100 fm (183 m) through 150 fm (274 m) depth contours. Boundaries for RCAs are defined by straight lines connecting a series of latitude/longitude coordinates....

  4. 17 CFR 274.302 - Form N-27I-1, notice of right of withdrawal and refund for variable life insurance... (United States)


    ... of withdrawal and refund for variable life insurance contractholders required pursuant to Rule 6e-2... for Exemptions § 274.302 Form N-27I-1, notice of right of withdrawal and refund for variable life insurance contractholders required pursuant to Rule 6e-2 (§ 270.6e-2 of this chapter). Editorial Note:...

  5. Oncogenic kinase NPM/ALK induces through STAT3 expression of immunosuppressive protein CD274 (PD-L1, B7-H1). (United States)

    Marzec, Michal; Zhang, Qian; Goradia, Ami; Raghunath, Puthiyaveettil N; Liu, Xiaobin; Paessler, Michele; Wang, Hong Yi; Wysocka, Maria; Cheng, Mangeng; Ruggeri, Bruce A; Wasik, Mariusz A


    The mechanisms of malignant cell transformation caused by the oncogenic, chimeric nucleophosmin (NPM)/anaplastic lymphoma kinase (ALK) remain only partially understood, with most of the previous studies focusing mainly on the impact of NPM/ALK on cell survival and proliferation. Here we report that the NPM/ALK-carrying T cell lymphoma (ALK+TCL) cells strongly express the immunosuppressive cell-surface protein CD274 (PD-L1, B7-H1), as determined on the mRNA and protein level. The CD274 expression is strictly dependent on the expression and enzymatic activity of NPM/ALK, as demonstrated by inhibition of the NPM/ALK function in ALK+TCL cells by the small molecule ALK inhibitor CEP-14083 and by documenting CD274 expression in IL-3-depleted BaF3 cells transfected with the wild-type NPM/ALK, but not the kinase-inactive NPM/ALK K210R mutant or empty vector alone. NPM/ALK induces CD274 expression by activating its key signal transmitter, transcription factor STAT3. STAT3 binds to the CD274 gene promoter in vitro and in vivo, as shown in the gel electromobility shift and chromatin immunoprecipitation assays, and is required for the PD-L1 gene expression, as demonstrated by siRNA-mediated STAT3 depletion. These findings identify an additional cell-transforming property of NPM/ALK and describe a direct link between an oncoprotein and an immunosuppressive cell-surface protein. These results also provide an additional rationale to therapeutically target NPM/ALK and STAT3 in ALK+TCL. Finally, they suggest that future immunotherapeutic protocols for this type of lymphoma may need to include the inhibition of NPM/ALK and STAT3 to achieve optimal clinical efficacy.

  6. Evaluation of a conserved HA274-288 epitope to detect antibodies to highly pathogenic avian influenza virus H5N1 in Indonesian commercial poultry. (United States)

    Wawegama, Nadeeka K; Tarigan, Simson; Indriani, Risa; Selleck, Paul; Adjid, Rm Abdul; Syafriati, Tati; Hardiman; Durr, Peter A; Ignjatovic, Jagoda


    A peptide enzyme linked immunosorbent assay (ELISA) based on an epitope in the haemagglutinin (HA) of avian influenza virus H5N1, amino acid positions 274-288 (HA274-288) was evaluated for detection of H5N1-specific antibodies. An optimized ELISA based on the tetrameric form of the HA274-288 epitope designated MP15 gave low background with non-immune chicken sera and detected vaccinated and infected birds. The HA274-288 epitope was highly conserved in Indonesian H5N1 strains and antibody responses were detected in the majority of the vaccinated chickens regardless of the H5N1 strain used for vaccination. The HA274-288 epitope was also conserved in the majority of H5N1 strains from the neighbouring Asian region, and other H5 subtypes potentially allowing for a wider use of the MP15 ELISA in H5N1 vaccinated and infected flocks. The MP15 ELISA results correlated significantly with haemagglutination inhibition (HI) test results and test sensitivity and specificity were 87% and 92%, respectively. The MP15 ELISA titres were significantly higher than the HI titres in all immune sera allowing for sera to be tested at a single dilution of 1:400 which is of advantage in routine surveillance. The study indicated that the MP15 ELISA is potentially useful for serological detection of H5N1 vaccinated or infected poultry and to have some advantages over the standard HI test for routine monitoring of flocks' immunity after vaccination.

  7. Corrective Action Decision Document/Closure Report for Corrective Action Unit 274: Septic Systems, Nevada Test Site, Nevada, Rev. No.: 0

    Energy Technology Data Exchange (ETDEWEB)

    Grant Evenson


    This Corrective Action Decision Document/Closure Report has been prepared for Corrective Action Unit 274, Septic Systems, Nevada Test Site (NTS), Nevada in accordance with the ''Federal Facility Agreement and Consent Order'' (1996). Corrective Action Unit (CAU) 274 is comprised of five corrective action sites (CASs): (1) CAS 03-02-01, WX-6 ETS Building Septic System; (2) CAS 06-02-01, Cesspool; (3) CAS 09-01-01, Spill Site; (4) CAS 09-05-01, Leaching Pit; and (5) CAS 20-05-01, Septic System. The purpose of this Corrective Action Decision Document/Closure Report is to provide justification and documentation supporting the closure of CAU 274 with no further corrective action. To achieve this, corrective action investigation (CAI) activities were performed from November 14 through December 17, 2005 as set forth in the CAU 274 Corrective Action Investigation Plan. The purpose of the CAI was to fulfill the following data needs as defined during the data quality objective (DQO) process: (1) Determine whether contaminants of concern (COCs) are present. (2) If contaminants of concern are present, determine their nature and extent. (3) Provide sufficient information and data to complete appropriate corrective actions. The CAU 274 dataset from the investigation results was evaluated based on the data quality indicator parameters. This evaluation demonstrated the quality and acceptability of the dataset for use in fulfilling the DQO data needs. Analytes detected during the CAI were evaluated against final action levels (FALs) established in this document. No analytes were detected at concentrations exceeding the FALs. No COCs have been released to the soil at CAU 274, and corrective action is not required. Therefore, the DQO data needs were met, and it was determined that no corrective action based on risk to human receptors is necessary for the site. All FALs were calculated using the industrial site worker scenario except for benzo(a)pyrene, which was

  8. The relationship of 274 children with respiratory infection and routine blood performance%274例住院患儿呼吸道病原体感染与白细胞数量变化的关系

    Institute of Scientific and Technical Information of China (English)

    袁红; 熊晓飞


    Objective: To discuss the relationship of children with respiratory infection and routine blood performance. Method: The investigated method is to analyze 274 hospitalized children with respiratory pathogen infection,and divide them into five categories according to the IFA detection results and clinical diagnosis:Simple virus infection group,the group combination of respiratory pathogen outside infection, MP merge virus and bacteria infection group, MP infection group, MP merge virus infection group, Compare the 5 groups of blood routine performance. Results: It shows that MP merger virus infections is the first-line reason in the 278 cases, accounting for 48.18%,and bacteria, MP merge viruses infection accounted for 7.66%, viruses and MP infection accounted for 20.07% and 16.79% respectively. The difference of Group 2 and other group is statistical y significant in WBC count (p <0.05), the difference of Group 4 and Group 3 is statistical y significant in lymphocyte count (p <0.05). Conclusions: MP merger virus infection is a common pattern of hospitalized children. The leukocytes count of the group combination of respiratory system outside damage is higher than respiratory pathogens infection disease in children.%目的:探讨儿童呼吸道感染情况及与血常规表现的关系。方法:回顾性分析274名住院呼吸道感染患儿病原体的感染情况,并将其按I F A检测结果和临床诊断分为5组:单纯病毒感染组、合并呼吸道病原体感染以外疾病组、细菌合并肺炎支原体及病毒感染组、肺炎支原体感染组、肺炎支原体合并病毒感染组(第5组),比较该5组患儿的血常规表现。结果:肺炎支原体合并病毒感染占呼吸道感染患儿首位(48.18%),细菌合并肺炎支原体及病毒感染占7.66%,病毒和肺炎支原体单独感染各占20.07%和16.79%。第2组的白细胞总数与其他各组的比较差异均有统计学意义(p<0.05),第4组与第3组

  9. 急诊抢救室处理非创伤急性腹痛274例临床调查及分析

    Institute of Scientific and Technical Information of China (English)

    梁亚鹏; 刘志祯; 尹其翔


    目的:对274例经急诊抢救室处理的非创伤急性腹痛患者临床资料进行回顾、总结、分析,强调对致命性非创伤急性腹痛的认识,提高抢救成功率。方法回顾急诊抢救室处理的274例以急性腹痛为主诉的非创伤患者的临床资料,对其病史、症状、体征、辅助检查及最终诊断进行总结、分析。结果经急诊抢救室处理以急性腹痛为主诉的非创伤患者,可迅速致命的疾病占12.04%(33例),延误病情后果严重可能危及生命的疾病占16.42%(45例),两者相加占28.46%。结论经急诊抢救室处理的非创伤急性腹痛潜在危险性巨大,需高度重视鉴别诊断,重点排除致命性疾病,从而改善预后。%Objective Through retrospective analysis of 274 cases with non traumatic acute abdominal pain managed in emergency rescue room, in order to strengthen the understanding of lethal acute abdominal pain and improve the success rate of rescue.Methods 274 patients with non traumatic acute abdominal pain managed in emergency rescue room of the affi liated hospital of Jiangsu university from January 2013 to December 2013 were analyzed retrospectively. The history, symptoms, signs, assistant examination andfi nal diagnosis of the patients were summarized and the focus was lethal acute abdominal pain.Results Among the patients with non traumatic acute abdominal pain managed in emergency rescue room, rapidly fatal diseases accounted for 12.04%(33 cases), life-threatening diseases accounted for 16.42%(45 cases). The two together accounted for 28.46%.Conclusion There was great potential medical risk in patients with non traumatic acute abdominal pain managed in emergency rescue room. We need to attach great importance to the differential diagnosis, emphatically exclude lethal disease, and improve the prognosis.


    Institute of Scientific and Technical Information of China (English)



    [目的]检测2 274名HBsAg阴性献血员血清抗-HBs、抗-HBc、HBV-DNA,探讨献血员筛查中检测抗-HBs、抗-HBc的必要性.[方法]对2 274名HBsAg阴性献血员血清ELISA法检测抗-HBs、抗-HBc,用PCR法检测HBV-DNA.[结果]检测者2 274名中①抗-HBs阳性/抗-HBc阴性59.3%,HBV-DNA阳性率0.2%;②抗-HBs阴性/抗-HBc阴性17.4%,HBV-DNA阳性率0.3%;③抗-HBs阴性/抗-HBc阳性1.4%,HBV-DNA阳性率6.3%:④抗HBs阳性/抗-HBc阳性21.9%,HBV-DNA阳性率0.2%.[结论]抗-HBs阴性/抗-HBc阳性群体中HBV-DNA阳性率最高(6.3%),提示献血员筛查中检测抗-HBs、抗-HBc,可以降低通过输血途径的感染率.

  11. The Effect of a Novel c.820C>T (Arg274Trp) Mutation in the Mitofusin 2 Gene on Fibroblast Metabolism and Clinical Manifestation in a Patient (United States)

    Kawalec, Maria; Kabzińska, Dagmara; Kochański, Andrzej; Krzyśko, Krystiana A.; Zabłocka, Barbara


    Charcot-Marie-Tooth disease type 2A (CMT2A) is an autosomal dominant axonal peripheral neuropathy caused by mutations in the mitofusin 2 gene (MFN2). Mitofusin 2 is a GTPase protein present in the outer mitochondrial membrane and responsible for regulation of mitochondrial network architecture via the fusion of mitochondria. As that fusion process is known to be strongly dependent on the GTPase activity of mitofusin 2, it is postulated that the MFN2 mutation within the GTPase domain may lead to impaired GTPase activity, and in turn to mitochondrial dysfunction. The work described here has therefore sought to verify the effects of MFN2 mutation within its GTPase domain on mitochondrial and endoplasmic reticulum morphology, as well as the mtDNA content in a cultured primary fibroblast obtained from a CMT2A patient harboring a de novo Arg274Trp mutation. In fact, all the parameters studied were affected significantly by the presence of the mutant MFN2 protein. However, using the stable model for mitofusin 2 obtained by us, we were next able to determine that the Arg274Trp mutation does not impact directly upon GTP binding. Such results were also confirmed for GTP-hydrolysis activity of MFN2 protein in patient fibroblast. We therefore suggest that the biological malfunctions observable with the disease are not consequences of impaired GTPase activity, but rather reflect an impaired contribution of the GTPase domain to other MFN2 activities involving that region, for example protein-protein interactions. PMID:28076385

  12. The Transient Accereting X-Ray Pulsar XTE J1946+274: Stability of the X-Ray Properties at Low Flux and Updated Orbital Solution

    CERN Document Server

    Marcu-Cheatham, Diana M; Kühnel, Matthias; Müller, Sebastian; Falkner, Sebastian; Caballero, Isabel; Finger, Mark H; Jenke, Peter J; Wilson-Hodge, Colleen A; Fürst, Felix; Grinberg, Victoria; Hemphill, Paul B; Kreykenbohm, Ingo; Klochkov, Dmitry; Rothschild, Richard E; Terada, Yukikatsu; Enoto, Teruaki; Iwakiri, Wataru; Wolff, Michael T; Becker, Peter A; Wood, Kent S; Wilms, Jöern


    We present a timing and spectral analysis of the X-ray pulsar XTE J1946+274 observed with Suzaku during an outburst decline in 2010 October and compare with previous results. XTE J1946+274 is a transient X-ray binary consisting of a Be-type star and a neutron star with a 15.75 s pulse period in a 172 d orbit with 2-3 outbursts per orbit during phases of activity. We improve the orbital solution using data from multiple instruments. The X-ray spectrum can be described by an absorbed Fermi-Dirac cutoff power law model along with a narrow Fe K line at 6.4 keV and a weak Cyclotron Resonance Scattering Feature (CRSF) at ~35 keV. The Suzaku data are consistent with the previously observed continuum flux versus iron line flux correlation expected from fluorescence emission along the line of sight. However, the observed iron line flux is slightly higher, indicating the possibility of a higher iron abundance or the presence of non-uniform material. We argue that the source most likely has only been observed in the sub...


    Energy Technology Data Exchange (ETDEWEB)

    Marcu-Cheatham, Diana M.; Pottschmidt, Katja [CRESST and Department of Physics, University of Maryland Baltimore County, 1000 Hilltop Circle, Baltimore, MD 21250 (United States); Kühnel, Matthias; Müller, Sebastian; Falkner, Sebastian; Kreykenbohm, Ingo [Dr. Karl Remeis-Observatory and ECAP, University Erlangen-Nuremberg, Sternwartstr. 7, Bamberg (Germany); Caballero, Isabel [Laboratoire AIM, CEA/IRFU, CNRS/INSU, Université Paris Diderot, CEA DSM/IRFU/SAp, F-91191 Gif-sur-Yvette (France); Finger, Mark H. [Universities Space Research Association, National Space Science and Technology Center, 320 Sparkman Drive, Huntsville, AL 35805 (United States); Jenke, Peter J. [University of Alabama in Huntsville, 301 Sparkman Drive, Huntsville, AL 35899 (United States); Wilson-Hodge, Colleen A. [Astrophysics Office, ZP 12, NASA Marshall Space Flight Center, Huntsville, AL 35812 (United States); Fürst, Felix [Cahill Center for Astronomy and Astrophysics, California Institute of Technology, Pasadena, CA 91125 (United States); Grinberg, Victoria [Massachusetts Institute of Technology, Kavli Institute for Astrophysics, Cambridge, MA 02139 (United States); Hemphill, Paul B.; Rothschild, Richard E. [University of California, San Diego, Center for Astrophysics and Space Sciences, 9500 Gilman Drive, La Jolla, CA 92093-0424 (United States); Klochkov, Dmitry [Institut für Astronomie und Astrophysik, Universität Tübingen (IAAT), Sand 1, Tübingen (Germany); Terada, Yukikatsu [Graduate School of Science and Engineering, Saitama University, 255 Simo-Ohkubo, Sakura-ku, Saitama City, Saitama 338-8570 (Japan); and others


    We present a timing and spectral analysis of the X-ray pulsar XTE J1946+274 observed with Suzaku during an outburst decline in 2010 October and compare with previous results. XTE J1946+274 is a transient X-ray binary consisting of a Be-type star and a neutron star with a 15.75 s pulse period in a 172 days orbit with 2–3 outbursts per orbit during phases of activity. We improve the orbital solution using data from multiple instruments. The X-ray spectrum can be described by an absorbed Fermi–Dirac cut-off power-law model along with a narrow Fe Kα line at 6.4 keV and a weak Cyclotron Resonance Scattering Feature (CRSF) at ∼35 keV. The Suzaku data are consistent with the previously observed continuum flux versus iron line flux correlation expected from fluorescence emission along the line of sight. However, the observed iron line flux is slightly higher, indicating the possibility of a higher iron abundance or the presence of non-uniform material. We argue that the source most likely has only been observed in the subcritical (non-radiation dominated) state since its pulse profile is stable over all observed luminosities and the energy of the CRSF is approximately the same at the highest (∼5 × 10{sup 37} erg s{sup −1}) and lowest (∼5 × 10{sup 36} erg s{sup −1}) observed 3–60 keV luminosities.


    Directory of Open Access Journals (Sweden)



    Full Text Available Una visión tridimensional de la resistencia al deslizamiento de superficies de pavimento respecto a variables como la velocidad y la razón de deslizamiento permiten caracterizar apropiadamente su comportamiento y facilitan el entendimiento del fenómeno. Sin embargo, los modelos utilizados actualmente para caracterizar la resistencia al deslizamiento solo evalúan un comportamiento bidimensional. La presente investigación utiliza los datos obtenidos por el deslizómetro ASTM E 274 para realizar una caracterización 3D del comportamiento de la resistencia al deslizamiento por medio de la fusión de dos reconocidos modelos bidimensionales de fricción (Modelo de Penn State y el Modelo de Rado. Los resultados de la investigación sugieren que la metodología propuesta presenta apropiados niveles de predicción para ser implementados en sistemas de gestión de infraestructura vial.

  15. Human rhinoviruses induce IL-35-producing Treg via induction of B7-H1 (CD274) and sialoadhesin (CD169) on DC. (United States)

    Seyerl, Maria; Kirchberger, Stefanie; Majdic, Otto; Seipelt, Joachim; Jindra, Christoph; Schrauf, Catharina; Stöckl, Johannes


    IL-35 is a heterodimer of EBV-induced gene 3 and of the p35 subunit of IL-12, and recently identified as an inhibitory cytokine produced by natural Treg in mice, but not in humans. Here we demonstrate that DC activated by human rhinoviruses (R-DC) induce IL-35 production and release, as well as a suppressor function in CD4(+) and CD8(+) T cells derived from human peripheral blood but not in naïve T cells from cord blood. The induction of IL-35-producing T cells by R-DC was FOXP3-independent, but blocking of B7-H1 (CD274) and sialoadhesin (CD169) on R-DC with mAb against both receptors prevented the induction of IL-35. Thus, the combinatorial signal delivered by R-DC to T cells via B7-H1 and sialoadhesin is crucial for the induction of human IL-35(+) Treg. These results demonstrate a novel pathway and its components for the induction of immune-inhibitory T cells.

  16. Neutron Diffraction Studies of a Class A beta-Lactamase Toho-1 E166A/R274N/R276N Triple Mutant

    Energy Technology Data Exchange (ETDEWEB)

    Blakeley, Matthew P. [Institut Laue-Langevin (ILL); Chen, Yu [ORNL; Afonine, Pavel [Lawrence Berkeley National Laboratory (LBNL)


    beta-Lactam antibiotics have been used effectively over several decades against many types of bacterial infectious diseases. However, the most common cause of resistance to the beta-lactam antibiotics is the production of beta-lactamase enzymes that inactivate beta-lactams by rapidly hydrolyzing the amide group of the beta-lactam ring. Specifically, the class A extended-spectrum beta-lactamases (ESBLs) and inhibitor-resistant enzymes arose that were capable of hydrolyzing penicillins and the expanded-spectrum cephalosporins and monobactams in resistant bacteria, which lead to treatment problems in many clinical settings. A more complete understanding of the mechanism of catalysis of these ESBL enzymes will impact current antibiotic drug discovery efforts. Here, we describe the neutron structure of the class A, CTX-M-type ESBL Toho-1 E166A/R274N/R276N triple mutant in its apo form, which is the first reported neutron structure of a beta-lactamase enzyme. This neutron structure clearly reveals the active-site protonation states and hydrogen-bonding network of the apo Toho-1 ESBL prior to substrate binding and subsequent acylation. The protonation states of the active-site residues Ser70, Lys73, Ser130, and Lys234 in this neutron structure are consistent with the prediction of a proton transfer pathway from Lys73 to Ser130 that is likely dependent on the conformation of Lys73, which has been hypothesized to be coupled to the protonation state of Glu166 during the acylation reaction. Thus, this neutron structure is in agreement with a proposed mechanism for acylation that identifies Glu166 as the general base for catalysis.

  17. Intraoperative cardiac arrest during anesthesia:a retrospective study of 218 274 anesthetics undergoing non-cardiac surgery in a US teaching hospital

    Institute of Scientific and Technical Information of China (English)

    AN Jian-xiong; Li-Ming Zhang; Erin A.Sullivan; GUO Qu-lian; John P.Williams


    Background Patient safety has been gained much more attention in recent years.The authors reviewed patients who had cardiac arrest in the operating rooms undergoing noncardiac surgery between January 1989 and December 2001 at the University of Pittsburgh Medical Center,USA.The main objectives of the study were to determine the incidence of intraoperative cardiac arrest,to identify possible causes of cardiac arrest and to explore amenable modifications.Methods With approval by the University of Pittsburgh Institutional Review Board,patients experienced cardiac arrest during surgery were retrieved from medical records,surgical operation and anesthesia records and pathological reports by searching the Medical Archival Retrieval System (MARS),a hospital electronic searching system.Cases of cardiac arrest were collected over a period of thirteen years from the Pre byteria University Hospital (PUH),USA.Results We found 23 cases of intraoperative cardiac arrests occurred in 218 274 anesthesia cases (1.1 per 10 000).Fourteen patients (60.8%) died in the operating room,leading to a mortality rate from all causes of 0.64 per 10 000 anesthetics.Immediate overall survival rate after arrest was 39% (9/23).Half of the patients (12/23) were emergency cases with 41% survival rate (5/12).One fourth of the arrests were trauma patients (6/23).Most arrest patients (87%,20/23) were American Society of Anesthesiologists Physical Status (ASA PS) Ⅳ and Ⅴ,while only three patients were ASA PS-Ⅰ,Ⅱ and Ⅲ,respectively.One case was attributable to an anesthesia-related cardiac arrest and recovered after successful resuscitation.Conclusions Most intraoperative cardiac arrests were not due to anesthesia-related causes.Anesthesia-related cardiac arrests might have a higher survival rate when compared to other possible causes of cardiac arrest in the operating room.

  18. The origin of the ∼274 cm{sup −1} additional Raman mode induced by the incorporation of N dopants and a feasible route to achieve p-type ZnO:N thin films

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Ping [Key Laborat of Optoelectronic Functional Materials, College of Physics and Electronic Engineering, Chongqing Normal University, Chongqing 401331 (China); Kong, Chunyang, E-mail: [Key Laborat of Optoelectronic Functional Materials, College of Physics and Electronic Engineering, Chongqing Normal University, Chongqing 401331 (China); Li, Wanjun, E-mail: [Key Laborat of Optoelectronic Functional Materials, College of Physics and Electronic Engineering, Chongqing Normal University, Chongqing 401331 (China); College of Physics, Chongqing University, Chongqing 401331 (China); Qin, Guoping [Key Laborat of Optoelectronic Functional Materials, College of Physics and Electronic Engineering, Chongqing Normal University, Chongqing 401331 (China); College of Physics, Chongqing University, Chongqing 401331 (China); Xu, Qing; Zhang, Hong [Key Laborat of Optoelectronic Functional Materials, College of Physics and Electronic Engineering, Chongqing Normal University, Chongqing 401331 (China); Ruan, Haibo [Research Center for Materials Interdisciplinary Sciences, Chongqing University of Arts and Sciences, Chongqing 402160 (China); Cui, Yuting [Key Laborat of Optoelectronic Functional Materials, College of Physics and Electronic Engineering, Chongqing Normal University, Chongqing 401331 (China); Fang, Liang [College of Physics, Chongqing University, Chongqing 401331 (China)


    Highlights: • ZnO:N films were grown on quartz substrates by RF magnetron sputtering technique. • ZnO:N thin films exhibit anomalous variation of ∼274 cm{sup −1} Raman mode. • The origin of the ∼274 cm{sup −1} mode induced by N dopants is Zn{sub i}-related defects. • Choosing appropriate N{sub 2} flow rate and annealing are the key to achieve p-type ZnO:N. - Abstract: Nitrogen doped ZnO films (ZnO:N) were deposited on quartz glass substrates by radio-frequency magnetron sputtering technique with various N{sub 2} flow rate mixed with Ar. Raman measurements indicate that the intensity of ∼274 cm{sup −1} mode of ZnO:N films exhibits an anomalous variation, which neither depends on N{sub 2} flow rate nor on N{sub O} acceptor content based on X-ray photoelectron spectroscopy (XPS) analysis. Combined with defect formation energy calculations, it is demonstrated that the ∼274 cm{sup −1} mode is attributed to Zn{sub i} defects which can be increased by the incorporation of N{sub O} acceptors, but suppressed by the presence of (N{sub 2}){sub O} double donors. XPS and optical absorption spectra suggest that ZnO:N film prepared under specific N{sub 2} flow rate (Ar:N{sub 2} = 3:1), has high concentration of acceptor N{sub O} with shallow states and the absence of shallow donor (N{sub 2}){sub O} defects, could be most likely to achieve p-type conductivity. But, at the same time, such specific ZnO:N film is the presence of shallow donor Zn{sub i} defects bonded with N{sub O} acceptors. Performing density functional calculations in conjunction with the climbing image nudged elastic band method shows that Zn{sub i} could be dissociated from Zn{sub i}–N{sub O} complexes by post-annealing treatment and N{sub O} acceptors would be activated to p-type ZnO:N. This is confirmed by our further Hall investigation, indicating that p-type ZnO:N can be achieved by choosing appropriate post-annealing treatment.

  19. Controle de infecção em cirurgia geral: resultado de um estudo prospectivo de 23 anos e 42.274 cirurgias Infection control in general surgery: results of a prospective study in 42,274 surgeries during 23 years

    Directory of Open Access Journals (Sweden)

    Edmundo Machado Ferraz


    Full Text Available OBJETIVO: O objetivo deste trabalho foi de avaliar uma metodologia simples adotada há 23 anos em um hospital público universitário no controle das infecções pós-cirúrgicas. MÉTODO: A casuística estudada compreende um total de 42.274 cirurgias realizadas no Serviço de Cirurgia Geral do Hospital das Clínicas da Universidade Federal de Pernambuco (UFPE (janeiro de 1977 a dezembro de 1999. Os dados foram obtidos através um sistema de busca ativa de infecção e de um sistema de vigilância epidemiológica de seguimento pós-operatório, no ambulatório de egressos. A Comissão de Controle de Infecção Hospitalar (CCIH do Hospital das Clínicas (HC da UFPE concentrou sua atuação na prevenção, dando ênfase ao: diagnóstico preciso dos casos de infecção; higiene corporal; controle das afecções associadas; internamento pré-operatório; cuidados com tricotomia; anti-sepsia e assepsia; técnica cirúrgica adequada; divulgação dos resultados e da relação infecção/cirurgião/anestesista e rigoroso controle de antimicrobianos. RESULTADOS: A taxa de infecção de ferida passou de índices em torno de 15-20% para os atuais 7,7%. A infecção urinária foi reduzida de 18,2% para 0,4%, e a infecção respiratória de 22,9% para 2,7%. A mortalidade em decorrência de infecção foi reduzida de 2,8% para os atuais 0,9% e a taxa de infecção de ferida em cirurgia limpa de 12,8% para 3,4%. Na cirurgia ambulatorial, das 27.580 operações a taxa de infecção de ferida foi de 0,4% e a mortalidade de 0,007%. CONCLUSÃO: O que tentamos comprovar com a divulgação de nossos resultados é que controle de infecção se faz com decisão política, força de vontade e motivação em controlar o problema da infecção hospitalar.BACKGROUND: The aim of this study was evaluate a methodology during 23 years in a public hospital used infection for control of surgeries. METHODS: A total of 42,274 surgeries in the General Surgery Division of the

  20. Densities and volume properties of (water + tert-butanol) over the temperature range of (274.15 to 348.15) K at pressure of 0.1 MPa

    Energy Technology Data Exchange (ETDEWEB)

    Egorov, Gennadiy I., E-mail: gie@isc-ras.r [Laboratory of Structure and Dynamics of Molecular and Ion-Molecular Solutions, Institute of Solution Chemistry, Russian Academy of Sciences, 1 Akademicheskaya Street, 153045 Ivanovo (Russian Federation); Makarov, Dmitriy M. [Laboratory of Structure and Dynamics of Molecular and Ion-Molecular Solutions, Institute of Solution Chemistry, Russian Academy of Sciences, 1 Akademicheskaya Street, 153045 Ivanovo (Russian Federation)


    The densities of {l_brace}water (1) + tert-butanol (2){r_brace} binary mixture were measured over the temperature range (274.15 to 348.15) K at atmospheric pressure using 'Anton Paar' digital vibrating-tube densimeter. Density measurements were carried out over the whole concentration range at (308.15 to 348.15) K. The following volume parameters were calculated: excess molar volumes and thermal isobaric expansivities of the mixture, partial molar volumes and partial molar thermal isobaric expansivities of the components. Concentration dependences of excess molar volumes were fitted with Redlich-Kister equation. The results of partial molar volume calculations using four equations were compared. It was established that for low alcohol concentrations at T {<=} 208 K the inflection points at x{sub 2} {approx} 0.02 were observed at concentration dependences of specific volume. The concentration dependences of partial molar volumes of both water and tert-butanol had extremes at low alcohol content. The temperature dependence of partial molar volumes of water had some inversion at x{sub 2} {approx} 0.65. The temperature dependence of partial molar volumes of tert-butanol at infinite dilution had minimum at {approx}288 K. It was discovered that concentration dependences of thermal isobaric expansivities of the mixture at small alcohol content and low temperatures passed through minimum.

  1. Incidence and causes of lower-limb amputations in the city of Ribeirão Preto from 1985 to 2008: evaluation of the medical records from 3,274 cases

    Directory of Open Access Journals (Sweden)

    Bruna Maria Bueno Barbosa

    Full Text Available ABSTRACT: Objective: It was to identify trends of traumatic and non-traumatic causes of lower limb amputations, as well as the role played by population aging, traffic violence increase, public health policy of diabetes control program and drivers anti-alcohol laws on these amputations. Method: Hospitalization data recorded in the discharge forms of 32 hospitals located in the region of Ribeirão Preto, Brazil, from 1985 to 2008 were analyzed. Result: A total of 3,274 lower-limb amputations were analyzed, of which 95.2% were related to non-traumatic causes, mainly infectious and ischemic complications of diabetes mellitus. Cancer (2.8% and congenital (1.3% causes were included in this group. Only 4.8% were related to traumatic causes. Traumatic amputation average rate was 1.5 amputations in 100,000 habitants with a slight tendency of increase in the last 5 years. Non-traumatic causes showed an average rate of 30.0 amputations for 100,000 habitants and remained relatively constant during the whole period. Non-traumatic were much more predominant in patients older than 60 years and traumatic amputations occurred more frequently in patients younger than 39 years. Conclusion: The overall rates of amputation and the rates of traumatic and non-traumatic amputations remained nearly constant during the study period. The impact of diabetes control policies and the introduction of traffic safety laws could not be identified on the amputation rates.

  2. 7 CFR 1822.274 - Loan closing. (United States)


    ... PRIMARILY FOR REAL ESTATE PURPOSES RURAL HOUSING LOANS AND GRANTS Rural Housing Site Loan Policies... Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS-COOPERATIVE... the OGC determines the Form to be inappropriate, real estate mortgage Form FmHA or its...

  3. 27 CFR 25.274 - Bond. (United States)


    ... is in effect. (b) Penal sum. The penal sum of a bond covering the premises of a pilot brewing plant... barrels by the rate of tax in 26 U.S.C. 5051. The penal sum of the bond (or total penal sum if...

  4. BDML Metadata: 274 [SSBD[Archive

    Lifescience Database Archive (English)

    Full Text Available Ce_KK_P002 BDML file for quantitative information about nuclear division dynamics o...f wild-type embryo quantitative information about nuclear division dynamics in wild-type embryo C. elegans nuclear division dynamic

  5. QTL Information Table: 274 [Q-TARO

    Lifescience Database Archive (English)

    Full Text Available qPEN-4 Morphological trait Panicle/flower Panicle exsertion RFLP C)Interval DHL IR6....P., and Khush, G.S. (2002). Molecular mapping of quantitative trait loci for plant growth, yield and yield related trait

  6. 50 CFR 216.274 - Mitigation. (United States)


    ..., personnel shall utilize all available sensor and optical systems (such as night vision goggles) to aid in... vision goggles shall be available to all ships and air crews, for use as appropriate. (3) Navy's Measures... patrol aircraft aircrews, and Anti-submarine Warfare (ASW)/Mine Warfare (MIW) helicopter crews...

  7. 21 CFR 558.274 - Hygromycin B. (United States)


    ... (airsac infection), blue comb (nonspecific infectious enteritis) As bacitracin methylene disalicylate or... infection), blue comb (nonspecific infectious enteritis) Feed containing not less than 25% of penicillin... respiratory disease (airsac infection), blue comb (nonspecific infectious enteritis) Combination...

  8. Elementary Statistics I--Mathematics 274 Course Syllabus, Fall 2001. (United States)

    Clark, Deborah L.

    This document features the syllabus for a course in Elementary Statistics/Mathematics at Southern University in Baton Rouge, LA. The course textbook, a course description, readings, goals, and course requirements are presented. Basic descriptive analysis and mathematical concepts commonly used in statistics are emphasized in the course. Topics…

  9. Dicty_cDB: VSH274 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available otein 6; Flags: Prec... 36 1.3 EF025354_1( EF025354 |pid:none) Synthetic construct multivalent an... 35 2.3 ...ivalent an... 35 2.3 EF025355_1( EF025355 |pid:none) Synthetic construct multival...( P27591 ) RecName: Full=23 kDa integral membrane protein; AltName... 35 2.3 EF025352_1( EF025352 |pid:none) Synthetic construct mult...ent an... 35 2.3 protein update 2009. 3.23 PSORT psg: 0.75 gvh: 0.57 alm: 0.12 top:

  10. 48 CFR 1816.405-274 - Award fee evaluation factors. (United States)


    ... factor, if used, must include consideration of risk management (including mission success, safety... procurement. Normally, technical and schedule considerations will be included in all CPAF contracts as... Procurement (Code HS) shall be notified prior to the determination of a zero award fee because of a...

  11. 40 CFR 52.274 - California air pollution emergency plan. (United States)


    ..., implementable provisions for taking emission control actions necessary to prevent ambient pollutant... Control District. (5) Bay Area Air Quality Management District. (6) Ventura County Air Pollution Control... under Rule 122; there is no time schedule for the Air Pollution Control Officer to initiate the call...

  12. Dicty_cDB: CHM274 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available from Patent WO0168911. 42 0.056 3 BD460584 |BD460584.1 Diagnosis of Diseases Asso...ciated with Cell Cycle. 42 0.056 3 BD452506 |BD452506.1 Diagnosis of Diseases Associated with Cell Cycle. 42

  13. 47 CFR 27.4 - Terms and definitions. (United States)


    ... Purpose Bankruptcy Remote Entity that is formed to build and operate the shared wireless broadband network... interoperable wireless broadband network operating on the 758-763 MHz and 788-793 MHz bands and the 763-768 MHz... of Commerce) Network Assets Holder. The Network Assets Holder is a Special Purpose Bankruptcy...

  14. 26 CFR 1.274-5T - Substantiation requirements (temporary). (United States)


    ... device with the aid of a logging program will constitute an adequate record. (D) Confidential information...) specifically designed and used to carry heavy tools, testing equipment, or parts if— (i) The shelves, racks,...

  15. Dicty_cDB: CFH274 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available ry Canis familiaris genomic, genomic survey sequence. 40 0.11 2 BQ507132 |BQ507132.2 EST614547 Generation of...sequence, mRNA sequence. 42 0.33 2 BQ507131 |BQ507131.1 EST614546 Generation of a set of potato cDNA clones

  16. 1935 15' Quad #274 Aerial Photo Mosaic Index (United States)

    Earth Data Analysis Center, University of New Mexico — Aerial Photo Reference Mosaics contain aerial photographs that are retrievable on a frame by frame basis. The inventory contains imagery from various sources that...

  17. Dicty_cDB: SLF274 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available 5215 |pid:none) Lymphocytic choriomeningitis virus... 39 0.20 AE014187_324( AE014187 |pid:none) Plasmodium f...alciparum 3D7 chromo... 37 0.75 EU480452_2( EU480452 |pid:none) Lymphocytic choriomeningitis... virus... 36 1.3 AF325214_2( AF325214 |pid:none) Lymphocytic choriomeningitis virus... 36 1.7 ( P...09992 ) RecName: Full=Nucleoprotein; AltName: Full=Nucleocapsid... 35 2.2 Y16308_1( Y16308 |pid:none) Lymphocytic choriomeningitis

  18. 7 CFR 274.6 - Replacement issuances to households. (United States)


    ... recipient's signature on the authorization document matches the signature on the ID card. In a Photo ID area... matches the serial number on the recipient's ID card; (3) Issue a replacement in accordance with... recipient's ID card. Any replacement which results in duplicate participation shall be considered...

  19. 49 CFR 178.274 - Specifications for UN portable tanks. (United States)


    ... be made of metallic materials suitable for forming. Non-metallic materials may be used for the... and vibration. All piping must be of a suitable metallic material. Welded pipe joints must be used..., and “Hydrogen, refrigerated liquid,” UN1966, that are marked “NOT FOR RAIL TRANSPORT” in letters of...

  20. Command and Control Career Ladder, AFSC 274X0. (United States)



  1. 38 CFR 21.274 - Revolving fund loan. (United States)


    ... continue in a rehabilitation program without such assistance. (b) Definition. The term advance means a non...) VOCATIONAL REHABILITATION AND EDUCATION Vocational Rehabilitation and Employment Under 38 U.S.C. Chapter 31... following conditions are present: (1) An Individualized Written Rehabilitation Plan, Individualized...

  2. Worldwide Report Telecommunications Policy, Research and Development No. 274. (United States)


    Text] [Lima EL COMERCIO in Spanish 27 Apr 83 p 3] 8143 CSO: 5500/2071 ARGENTINA BRIEFS SATELLITE GROUND STATION—Buenos Aires, 5 May (TELAM...Iquitos, Arequipa, lea, Huaraz, Cuzco and Tacna. [TextJ [.Lima EL COMERCIO in Spanish 3 May 83 p a 8 PY] CSO; 5500/2074 ST LUCIA DETAILED REVIEW OF

  3. Dicty_cDB: SLC274 [Dicty_cDB

    Lifescience Database Archive (English)


  4. 40 CFR 180.274 - Propanil; tolerances for residues. (United States)


    ....05 Horse, meat byproducts 1.0 Milk 0.05 Poultry, fat 0.05 Poultry, meat 0.10 Poultry, meat byproducts 0.50 Rice, bran 40 Rice, grain 10 Rice, hulls 30 Rice, straw 75 Sheep, fat 0.10 Sheep, meat 0.05 Sheep, meat byproducts 1.0 (b) Section 18 emergency exemptions. (c) Tolerances with...

  5. Nanoose Range Current Characteristics at 274m Depth (United States)


    data point is the resultant vector summation of the actual current sampled every 1/8 turn of the Savonius rotor speed sensor over a 112.5-second...E. Woodward and Gerald F. Appel, July 1973 5. NOAA-TM-NOS-NOIC-3, Effects of Vertical Motion on Vector Averaging ( Savonius Rotor) and Electromagnetic...IAVTORPSTh tracking ranges. The measurement apparatus entails’a Hydro Products Savonius rotor and directional vane follower. These sensors are Lpart of the

  6. 77 FR 274 - Combined Notice of Filings #1 (United States)


    ...: ER12-670-000. Applicants: Rhode Island LFG Genco LLC. Description: Rhode Island LFG Genco LLC MBR... p.m. ET 1/12/12. Docket Numbers: ER12-674-000. Applicants: Rhode Island Engine Genco LLC. Description: Rhode Island Engine Genco LLC MBR Tariff to be effective 2/20/2012. Filed Date:...

  7. 37 CFR 2.74 - Form and signature of amendment. (United States)


    ... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Form and signature of... signature of amendment. (a) Form of Amendment. Amendments should be set forth clearly and completely... record. (b) Signature. A request for amendment of an application must be signed by the applicant,...

  8. 7 CFR 274.1 - State agency issuance responsibility. (United States)


    ... perpetual inventory records and the monthly reports of the coupon issuer or bulk storage point. This review... firm with expertise in auditing and accounting. State agencies may use the results of reviews of coupon issuers by independent audit or accounting firms as long as the food coupon issuance operations of...

  9. Dicty_cDB: SHH274 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available e 2 map 6245135-6357017 strain AX4, complete sequence. 42 0.72 5 AF435076 |AF435076.2 Tetrahymena thermophila anlage...n stage induced 1 protein (ASI1) and anlagen stage induced 2 protein (ASI

  10. OC274L01: WHOI cruise 274 leg 01 aboard the R/V Oceanus from 1996-02-01 - 1996-02-24 (NODC Accession 0078920) (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Post-cruise download of raw data from shipboard computer(s) as furnished by the Woods Hole Oceanographic Institution Shipboard Scientific Support Group and archived...

  11. Deployment and optimization of biomacromolecule molecular dynamics simulation process on hundred trillion times clusterto 6 720 CPU cores in this task, the total computing speed accumulated to 2 274 ns/d, which offers a new approach to run the molec...%生物大分子的分子动力学模拟过程在百万亿次集群上的部署优化

    Institute of Scientific and Technical Information of China (English)

    潘龙强; 耿存亮; 慕宇光; 刘鑫; 胡毅; 潘景山; 周亚滨; 龚斌; 王禄山


    simultaneously used up to 6 720 CPU cores in this task, the total computing speed accumulated to 2 274 ns/d, which offers a new approach to run the molecular dynamics over ten thousand CPU cores.

  12. 26 CFR 1.274-4 - Disallowance of certain foreign travel expenses. (United States)


    ... paragraph (d) of this section) constitutes 25 percent or more of the total time on such travel. (c) Travel... percent or more of travel time under paragraph (d) of this section and for purposes of allocating expenses... percent or more of travel time—(1) In general. This section does not apply to any expense of...


    Energy Technology Data Exchange (ETDEWEB)

    Ribaudo, Joseph; Lehner, Nicolas; Christopher Howk, J. [Department of Physics, University of Notre Dame, Notre Dame, IN 46556 (United States); Werk, Jessica K.; Xavier Prochaska, J. [UCO/Lick Observatory, University of California at Santa Cruz, Santa Cruz, CA 95064 (United States); Tripp, Todd M.; Meiring, Joseph D. [Department of Astronomy, University of Massachusetts, Amherst, MA 01003 (United States); Tumlinson, Jason [Space Telescope Science Institute, Baltimore, MD 21218 (United States)


    We present UV and optical observations from the Cosmic Origins Spectrograph on the Hubble Space Telescope and Keck of a z = 0.27395 Lyman limit system (LLS) seen in absorption against the QSO PG1630+377. We detect H I absorption with log N(H I) = 17.06 {+-} 0.05 as well as Mg II, C III, Si III, and O VI in this system. The column densities are readily explained if this is a multi-phase system, with the intermediate and low ions arising in a very low metallicity ([Mg/H] = -1.71 {+-} 0.06) photoionized gas. We identify via Keck spectroscopy and Large Binocular Telescope imaging a 0.3 L{sub *} star-forming galaxy projected 37 kpc from the QSO at nearly identical redshift (z = 0.27406 and {Delta}v = -26 km s{sup -1}) with near solar metallicity ([O/H] = -0.20 {+-} 0.15). The presence of very low metallicity gas in the proximity of a near-solar metallicity, sub-L{sub *} galaxy strongly suggests that the LLS probes gas infalling onto the galaxy. A search of the literature reveals that such low-metallicity LLSs are not uncommon. We found that 50% (4/8) of the well-studied z {approx}< 1 LLSs have metallicities similar to the present system and show sub-L{sub *} galaxies with {rho} < 100 kpc in those fields where redshifts have been surveyed. We argue that the properties of these primitive LLSs and their host galaxies are consistent with those of cold mode accretion streams seen in galaxy simulations.

  14. Regulation of the histone acetyltransferase activity of hMOF via autoacetylation of Lys274

    Institute of Scientific and Technical Information of China (English)

    Bingfa Sun; Shunling Guo; Qingyu Tang; Chen Li; Rong Zeng; Zhiqi Xiong; Chen Zhong; Jianping Ding


    Dear Editor, Males-absent-on-the-first (MOF, also called MYST1 or KAT8) is a histone acetyltransferase (HAT) belonging to the MOZ, Ybf2/Sas3, Sas2 and Tip60 (MYST) family.MOF has been shown to possess a specific HAT activity towards Lysl6 of histone H4 (H4K16) [1].Homozygous knockout of MOF in mice results in loss of H4K16 acetylation and embryonic lethality, indicating that MOF and H4K16 acetylation are essential for embryogenesis and genome stability in mammals [2].Downregulation of human MOF (hMOF) leads to dramatic nuclear morphological deformation and inhibition of cell cycle progression [3], and has recently been correlated with primary breast carcinoma and medulloblastoma [4].

  15. Histopathologic study on muscle diseases among Koreans (274 muscle biopsy analysis).


    Chi, J. G.; Koo, H S; Roh, J K


    All the diagnostic muscle biopsy cases were collected from the file of Department of Pathology, Seoul National University Hospital during June 1976 to December 1978. Slides were reviewed and correlated with clinical informations. Two hundred seventy four cases showed pathological changes, which were classified into six large groups (Table 1). Neurogenic atrophy was most common, 97 cases (35%), including 71 cases of motor neuron disease and 22 cases of peripheral neuropathy. Muscular dystrophy...

  16. Comparative genomics of 274 Vibrio cholerae genomes reveals mobile functions structuring three niche dimensions

    NARCIS (Netherlands)

    Dutilh, Bas E; Thompson, Cristiane C; Vicente, Ana C P; Marin, Michel A; Lee, Clarence; Silva, Genivaldo G Z; Schmieder, Robert; Andrade, Bruno G N; Chimetto, Luciane; Cuevas, Daniel; Garza, Daniel R; Okeke, Iruka N; Aboderin, Aaron Oladipo; Spangler, Jessica; Ross, Tristen; Dinsdale, Elizabeth A; Thompson, Fabiano L; Harkins, Timothy T; Edwards, Robert A


    BACKGROUND: Vibrio cholerae is a globally dispersed pathogen that has evolved with humans for centuries, but also includes non-pathogenic environmental strains. Here, we identify the genomic variability underlying this remarkable persistence across the three major niche dimensions space, time, and h

  17. 7 CFR 274.10 - Use of identification cards and redemption of coupons by eligible households. (United States)


    ... at communal dining facilities authorized by FNS for that purpose. Any household eligible for and interested in using communal dining facilities in those States or project areas where restaurants are... out-of-office interviews as specified in § 273.2(e)(2). However, the State agency shall replace...

  18. 26 CFR 1.274-3 - Disallowance of deduction for gifts. (United States)


    ... reason of the employee's length of service (including an award upon retirement), productivity, or safety... to an employee by reason of the employee's length of service (including retirement), productivity, or... the wife has a bona fide business connection with the taxpayer independently of her relationship...

  19. 7 CFR 274.12 - Electronic Benefit Transfer issuance system approval standards. (United States)


    ... equipped to accept EBT cards. (viii) Disclosure information regarding adjustments and a household's rights... transmission. Any of the network security measures may be utilized together or separately and may be applied at... acceptance testing. The Department reserves the right to participate in the Functional Demonstration if...

  20. TLR3 triggering regulates PD-L1 (CD274) expression in human neuroblastoma cells

    NARCIS (Netherlands)

    Boes, Marianne; Meyer-Wentrup, Friederike


    Neuroblastoma is the most common extracranial solid tumor in children, causing 12% of all pediatric cancer mortality. Neuroblastoma specific T-cells have been detected in patients, but usually fail to attack and eradicate the tumors. Tumor immune evasion may thus play an important role in neuroblast

  1. 17 CFR 274.128 - Form N-CSR, certified shareholder report. (United States)


    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Form N-CSR, certified... Form N-CSR, certified shareholder report. This form shall be used by registered management investment... of this chapter. Editorial Note: For Federal Register citations affecting Form N-CSR, see the List...

  2. 8 CFR 274a.2 - Verification of identity and employment authorization. (United States)


    ...; (iv) In the case of electronically retained Forms I-9, a retrieval system that includes an indexing... electronic generation or storage system must not be subject, in whole or in part, to any agreement (such as a..., including all procedures relating to its use; and (ii) The indexing system. (6) An “indexing system” for...

  3. SU-E-T-274: Does Atmospheric Oxygen Affect the PRESAGE Dosimeter?

    Energy Technology Data Exchange (ETDEWEB)

    Alqathami, M; Ibbott, G [UT MD Anderson Cancer Center, Houston, TX (United States); Blencowe, A [The University of South Australia, South Australia, SA (Australia)


    Purpose: To experimentally determine the influence of atmospheric oxygen on the efficiency of the PRESAGE dosimeter and its reporting system. Methods: Batches of the reporting system – a mixture of chloroform and leuchomalachite green dye – and PRESAGE were prepared in aerobic and anaerobic conditions. For anaerobic batches, samples were deoxygenated by bubbling nitrogen through the dosimeter precursors or reporting system for 10 min. The dosimeters and reporting systems were prepared in spectrophotometric cuvettes and glass vials, respectively, and were irradiated with 6 MV photons to various radiation doses using a clinical linear accelerator. Changes in optical density of the dosimeters and reporting system before and after irradiation were measured using a spectrophotometer. In addition, the concentrations of dissolved oxygen were measured using a dissolved oxygen meter. Results: The experiments revealed that oxygen has little influence on the characteristics of PRESAGE, with the radical initiator oxidizing the leucomalachite green even in the presence of oxygen. However, deoxygenation of the reporting system leads to an increase in sensitivity to radiation dose by ∼ 30% when compared to the non-deoxygenated system. A slight improvement in sensitivity (∼ 5%) was also achieved by deoxygenating the PRESAGE precursor prior to casting. Measurement of the dissolved oxygen revealed low levels (0.4 ppm) in the polyurethane precursor used to fabricate the dosimeters, as compared to water (8.6 ppm). In addition, deoxygenation had no effect on the retention of the post-response absorption value of the PRESAGE dosimeter. Conclusion: The results suggest that the presence of oxygen does not inhibit the radiochromic properties of the PRESAGE system. In addition, there were no observed changes in the dose linearity, absorption spectrum and post-response photofading characteristics of the PRESAGE under the conditions investigated.

  4. 77 FR 28588 - Proposed Priorities-American Overseas Research Centers Program; CFDA Number 84.274A (United States)


    ... globally competent workforce. For these reasons, we propose Priority 1--Centers that Expand the Diversity... other things and to the extent practicable--the costs of cumulative regulations; (3) In choosing among... this document is the document published in the Federal Register. Free Internet access to the...

  5. 26 CFR 1.274-2 - Disallowance of deductions for certain expenses for entertainment, amusement, recreation, or travel. (United States)


    ... were to provide occasional free dinners at the hotel for a customer who patronized the hotel. (5... include, but are not limited to, country clubs, golf and athletic clubs, airline clubs, hotel clubs, and... which is claimed as a business expense by the taxpayer, which satisfies the personal, living, or...

  6. 76 FR 9320 - Foreign-Trade Zone 274-Butte-Silver Bow, MT; Application for Manufacturing Authority REC Silicon... (United States)


    ... Authority REC Silicon (Polysilicon and Silane Gas) Butte, MT An application has been submitted to the..., requesting manufacturing authority on behalf of REC Silicon, located in Butte, Montana. The application was... regulations of the Board (15 CFR part 400). It was formally filed on February 11, 2011. The REC...

  7. SU-E-J-274: Responses of Medulloblastoma Cells to Radiation Dosimetric Parameters in Intensity-Modulated Radiation Therapy

    Energy Technology Data Exchange (ETDEWEB)

    Park, J [Dept. of Pediatrics, Stanford University School of Medicine, Stanford, CA (United States); Molecular Imaging Program at Stanford, Stanford, CA (United States); Bio-X Program, Stanford, CA (United States); Research Institute of Biomedical Engineering, The Catholic University of Korea, Seoul (Korea, Republic of); Park, J [Proton Therapy Center, National Cancer Center, Goyang (Korea, Republic of); Rogalla, S; Contag, C [Dept. of Pediatrics, Stanford University School of Medicine, Stanford, CA (United States); Molecular Imaging Program at Stanford, Stanford, CA (United States); Bio-X Program, Stanford, CA (United States); Woo, D [Asan Institute for Life Sciences, Asan Medical Center, Seoul (Korea, Republic of); Lee, D [Research Institute of Biomedical Engineering, The Catholic University of Korea, Seoul (Korea, Republic of); Asan Institute for Life Sciences, Asan Medical Center, Seoul (Korea, Republic of); Park, H [Dept. of Radiation Oncology, Ajou University School of Medicine, Suwon (Korea, Republic of); Suh, T [Research Institute of Biomedical Engineering, The Catholic University of Korea, Seoul (Korea, Republic of); Dept. of Biomedical Engineering, The Catholic University of Korea, Seoul (Korea, Republic of)


    Purpose: To evaluate radiation responses of the medulloblastoma cell line Daoy in intensity-modulated radiation therapy (IMRT), quantitative variations to variable radiation dosimetic parameters were tracked by bioluminescent images (BLIs). Methods: The luciferase and green fluorescent protein positive Daoy cells were cultured on dishes. The medulloblastoma cells irradiated to different dose rate, interval of fractionated doses, field margin and misalignment, and dose uniformity in IMRT were monitored using bioluminescent images. The cultured cells were placed into a dedicated acrylic phantom to deliver intensity-modulated fluences and calculate accurate predicted dose distribution. The radiation with dose rate from 0.5 Gy/min to 15 Gy/min was irradiated by adjusting monitor unit per minute and source-to-surface distances. The intervals of fractionated dose delivery were changed considering the repair time of double strand breaks (DSB) revealed by straining of gamma-H2AX.The effect of non-uniform doses on the cells were visualized by registering dose distributions and BLIs. The viability according to dosimetric parameters was correlated with bioluminescent intensities for cross-check of radiation responses. Results: The DSB and cell responses due to the first fractionated dose delivery significantly affected final tumor control rather than other parameters. The missing tumor volumes due to the smaller field margin than the tumor periphery or field misalignment caused relapse of cell responses on BLIs. The dose rate and gradient had effect on initial responses but could not bring out the distinguishable killing effect on cancer cells. Conclusion: Visualized and quantified bioluminescent images were useful to correlate the dose distributions with spatial radiation effects on cells. This would derive the effective combination of dose delivery parameters and fractionation. Radiation responses in particular IMRT configuration could be reflected to image based-dose re-optimization.

  8. Nuclear Technology. Course 27: Metrology. Module 27-4, Angle Measurement Instruments, Optical Projections and Surface Texture Gages. (United States)

    Selleck, Ben; Espy, John

    This fourth in a series of eight modules for a course titled Metrology describes the universal bevel protractor and the sine bar, the engineering microscope and optical projector, and several types of surface texture gages. The module follows a typical format that includes the following sections: (1) introduction, (2) module prerequisites, (3)…

  9. Monedas de Guerra y triunfo de Octaviano. Las series CAESAR DIVI F e IMP CAESAR (RIC I 250 - 274)



    En 2014 hemos celebrado el bimilenario de la muerte de Augusto, uno de los personajes más destacados del mundo antiguo. Su política y su moral supusieron un importante cambio para el Estado Romano, gracias en parte a su magistral uso de la propaganda política. Octaviano, desde que su tío-abuelo le convirtiera en su heredero, hizo buen uso de la manipulación pública para conseguir sus fines durante el triunvirato y el conflicto posterior. Presentamos una recopilación de su propaganda política ...

  10. 17 CFR 274.11d - Form N-6, registration statement of separate accounts organized as unit investment trusts that... (United States)


    ... variable life insurance policies. Form N-6 shall be used as the registration statement to be filed pursuant... statement of separate accounts organized as unit investment trusts that offer variable life insurance... insurance policies to register as unit investment trusts. This form shall also be used for...

  11. NUCLEAR CHEMISTRY: Element 107 Leaves the Table Unturned. (United States)

    Service, R F


    This week, an international team of chemists reported on the first successful analysis of the chemical properties of bohrium, element 107. The results matched predictions, postponing scientists' hopes of seeing interesting deviations from theory among ultraheavy elements.

  12. The AFGL Four Color Infrared Sky Survey: Catalog of Observations at 4. 2, 11.0, 19.8 and 27.4 micrometers (United States)


    in m-. SIt knn ’r i- - 0 NW NO *ý in M -I ni q ~ o m o m m mm w r q t4 v m0 V V O * N NWN NNN NNV N N N N NNN NV NN NVm wNV VN C’tNNDMnNN - M0 O- MiO ...Nn -" C4111n f C4 C4 - - - - - J’ - -M~ - q--’e-- m -, rn - 0 v I 1,O’ 0.i 0OOI N O -Oi n-7 qr-Miý inUL q -,C4U u- 4 8W’i MiO InOO &nn00’ Mii 0iii O...Ch r. 9l i in9 CID In0 04 inn i *i 901 n1 - D j in 0 1 0 in in -t mL Wm w W 7 7 m m - -- 7 -ý - -co 9 w 010 MImD. 10( 9nm-0o M-(100109 -- ,0 . 0020 0

  13. SU-E-T-274: Radiation Therapy with Very High-Energy Electron (VHEE) Beams in the Presence of Metal Implants

    Energy Technology Data Exchange (ETDEWEB)

    Jensen, C; Palma, B; Qu, B; Maxim, P; Loo, B; Bazalova, M [Department of Radiation Oncology, Stanford University, Stanford, CA (United States); Hardemark, B; Hynning, E [RaySearch Laboratories, Stockholm (Sweden)


    Purpose: To evaluate the effect of metal implants on treatment plans for radiation therapy with very high-energy electron (VHEE) beams. Methods: The DOSXYZnrc/BEAMnrc Monte Carlo (MC) codes were used to simulate 50–150MeV VHEE beam dose deposition and its effects on steel and titanium (Ti) heterogeneities in a water phantom. Heterogeneities of thicknesses ranging from 0.5cm to 2cm were placed at 10cm depth. MC was also used to calculate electron and photon spectra generated by the VHEE beams' interaction with metal heterogeneities. The original VMAT patient dose calculation was planned in Eclipse. Patient dose calculations with MC-generated beamlets were planned using a Matlab GUI and research version of RayStation. VHEE MC treatment planning was performed on water-only geometry and water with segmented prostheses (steel and Ti) geometries with 100MeV and 150MeV beams. Results: 100MeV PDD 5cm behind steel/Ti heterogeneity was 51% less than in the water-only phantom. For some cases, dose enhancement lateral to the borders of the phantom increased the dose by up to 22% in steel and 18% in Ti heterogeneities. The dose immediately behind steel heterogeneity decreased by an average of 6%, although for 150MeV, the steel heterogeneity created a 23% increase in dose directly behind it. The average dose immediately behind Ti heterogeneities increased 10%. The prostate VHEE plans resulted in mean dose decrease to the bowel (20%), bladder (7%), and the urethra (5%) compared to the 15MV VMAT plan. The average dose to the body with prosthetic implants was 5% higher than to the body without implants. Conclusion: Based on MC simulations, metallic implants introduce dose perturbations to VHEE beams from lateral scatter and backscatter. However, when performing clinical planning on a prostate case, the use of multiple beams and inverse planning still produces VHEE plans that are dosimetrically superior to photon VMAT plans. BW Loo and P Maxim received research support from RaySearch laboratories; B Hardemark and E Hynning are employees of RaySearch.

  14. 17 CFR 274.303 - Form N-27I-2, notice of withdrawal right and statement of charges for variable life insurance... (United States)


    ... withdrawal right and statement of charges for variable life insurance contractholders required pursuant to... variable life insurance contractholders required pursuant to Rule 6e-2 (§ 270.6e-2 of this chapter). Editorial Note: For Federal Register citations affecting Form N-27I-2, see the List of CFR Sections...

  15. Real-time PCR detection and quantification of fish probiotic Phaeobacter strain 27-4 and fish pathogenic Vibrio in microalgae, rotifer, Artemia and first feeding turbot (Psetta maxima) larvae

    DEFF Research Database (Denmark)

    Prol, M.J.; Bruhn, Jesper Bartholin; Pintado, J.


    and in presence of microalgae (Isochrysis galbana), rotifers (Brachionus plicatilis), Artemia nauplii or turbot (Psetta maxima) larvae by real-time PCR based on primers directed at genetic loci coding for antagonistic and virulence-related functions respectively. The optimized protocol was used to study...

  16. On suitability of present alumina standart YS/T274-1998 and GB/T4294-1997%论氧化铝行业产品标准的适宜性

    Institute of Scientific and Technical Information of China (English)

    李敏; 张明阳



  17. Automatic Parallelization of Scientific Application

    DEFF Research Database (Denmark)

    Blum, Troels

    In my PhD work I show that it is possible to run unmodified Python/NumPy code on modern GPUs. This is done by using the Bohrium runtime system to translate the NumPy array operations into an array based bytecode sequence. Executing these byte-codes on two GPUs from different vendors shows great...... performance gains. Scientists working with computer simulations should be allowed to focus on their field of research and not spend excessive amounts of time learning exotic programming models and languages. We have with Bohrium achieved very promising results by starting out with a relatively simple approach....... This has lead to more specialized methods as I have shown with the work done with both specialized, and parametrizied kernels. Both have their benefits and recognizable use cases. We achieved clear performance benefits without any significant negative impact on overall application performance. Even...

  18. Battling memory requirements of array programming through streaming

    DEFF Research Database (Denmark)

    Kristensen, Mads Ruben Burgdorff; Avery, James Emil; Blum, Troels;


    A barrier to efficient array programming, for example in Python/NumPy, is that algorithms written as pure array operations completely without loops, while most efficient on small input, can lead to explosions in memory use. The present paper presents a solution to this problem using array streaming......, implemented in the automatic parallelization high-performance framework Bohrium. This makes it possible to use array programming in Python/NumPy code directly, even when the apparent memory requirement exceeds the machine capacity, since the automatic streaming eliminates the temporary memory overhead...... streaming, yielding corresponding improvements in speed and utilization of GPGPU-cores. The streaming-enabled Bohrium effortlessly runs programs on input sizes much beyond sizes that crash on pure NumPy due to exhausting system memory....

  19. 76 FR 76181 - Certain Electronic Paper Towel Dispensing Devices and Components Thereof; Issuance of General... (United States)


    ...,387,274 (``the '274 patent''). The complainant named as respondents Kruger Products LP of Mississauga...Pak Chicago; (2) to redefine ``Kruger'' to ``Kruger Products and/or KTG USA''; (3) to indicate...

  20. Gclust Server: 78480 [Gclust Server

    Lifescience Database Archive (English)

    Full Text Available 78480 PoTR_558592 Cluster Sequences Related Sequences(274) 397 eugene3.00050207 1 1...ces Cluster Sequences Link to related sequences Related Sequences(274) Sequence length 397 Representative annotation eugene

  1. Rock Art Glossary: A Multilingual Dictionary, Expanded Second Edition (First Edition 2001. Edited by Robert G. Bednarik, Ahmed Achrati, Tang Huisheng, Alfred Muzzolini, George Dimitriadis, Dario Seglie, Fernando Coimbra, Yakov A. Sher and Mario Consens. Australian Rock Art Research Association, Inc., Melbourne, 2010; 274 Pages, in English, Arabic, Chinese, French, German, Greek, Italian, Portuguese, Russian and Spanish, with Translation Tables. Price $A 38.00, ISBN 978-0-646-53471-8

    Directory of Open Access Journals (Sweden)

    Shu-Kun Lin


    Full Text Available This is the first dictionary compiled specifically for rock art research. It follows the publication of an English rock art glossary in the journal Rock Art Research in November 2000. To be adopted by the International Federation of Rock Art Organisations (IFRAO, it has been translated by some of the world’s foremost scholars in the field into Arabic, Chinese, French, German, Greek, Italian, Portuguese, Spanish and Russian. In a discipline that has hitherto been without an agreed terminology, even communication within a single language has been difficult. The proliferation of idiosyncratic terminologies of often academically isolated researchers, many of which have been used by only one scholar, has not only retarded progress and the transference of knowledge, it has led to countless misunderstandings and even personal feuds. The purpose of this dictionary is to create a single terminological standard as well as a cross-lingual uniformity of usage. It focuses particularly on scientific aspects, technical applications and epistemological rigour. It does not set out to create a terminological straitjacket for the discipline, but a common standard of reference, particularly in areas that have in the past been susceptible to greatly differing interpretations. This dictionary comprises sections in ten languages, each listing the same terms alphabetically. It also contains a table interlinking all of these languages, listing all terms explained. This translation table is organised alphabetically according to the English terms. The volume is indispensable for scientific translators, rock art scholars, archaeologists and others concerned with aspects of pre-Historic rock art, and is also intended for the guidance of students and authors working in this field.

  2. Adaptation of Impact Questions from an Existing Toolkit Provided Clear Assessment of Valued Service Elements and Desirable Service Improvements in a Primary Health Care Library and Information Service. A Review of: Urquhart, C., Thomas, R., Ovens, J., Lucking, W., & Villa, J. (2010. Planning changes to health library services on the basis of impact assessment. Health Information and Libraries Journal, 27(4, 277-285. doi: 10.1111/j.1471-1842.2010.00900.x

    Directory of Open Access Journals (Sweden)

    Kate Kelly


    Full Text Available Objective – To provide an action plan for the Knowledge, Resource and Information Service (KRIS based on an impact assessment of current services, satisfaction with current services, and views on desirable improvements to service and service delivery.Design – Questionnaire for KRIS service users and interviews with KRIS staff.Setting – Two locations served by KRIS in the north and south of Bristol City in the UK – one a health promotion service and one a National Health Service (NHS teaching hospital.Subjects – A convenience sample of a total of 244 users of the library services at the two locations, 121 users at the health promotion service site and 123 users at the hospital site.Methods – A questionnaire designed for a previous NHS library service impact study was adapted for use with staff other than health workers, since teachers and youth workers, for example, also used the health promotion service. The researchers circulated the questionnaire by mail and email to prospective respondents. The questionnaire asked participants to reflect on the most recent time they had used KRIS services and provide details on the purpose of use, what elements of the service they used, satisfaction with the service or the information provided, the immediate impact on their work, and its probable contribution to future work. It also asked about desirable improvements and how KRIS contributed to the respondents’ work and continuing professional development. The researchers interviewed KRIS staff face to face and asked for their views on the history of the service and future developments.Main Results – The overall response rate was 62.3% (152/244, with similar responses from each site. Community nurses and midwives were the largest group of respondents (n=31, 20.4%, followed by managers and administrators (n=24, 15.8%.Both sites reported health promotion activities as the dominant reason for use. Health promotion leaflets (n=94, 61.8% and resources for loan (n=57, 37.5% were the top two service elements used, with literature searching third (n=46, 30.3%.The service completely met the needs of 93% (n=141 of respondents, with 97.4% (n=148 reporting being wholly satisfied that information was delivered in time.In terms of the immediate cognitive impact of the information obtained, 93% (n=141 reported obtaining relevant information, 76% (n=115 current information, and 72% (n=109 accurate information. Nearly 70% were distributing information or resources to other people, and 68% were sharing or discussing information provided with colleagues. Nobody claimed that they had found little or nothing of value.Advice to patients, clients or carers was the most frequently cited impact category (n=104, 68%, followed by advice to colleagues (n=84, 55.3%.The main strengths of the service were the perceived reliability of the service, the current awareness and alerting service run from one site, and literature searching support for commissioning and public health enquiries. Respondents reported saving time, and the main cognitive impact was the perceived relevance of the information obtained. Service weaknesses identified related to accessibility issues such as parking, opening hours, and staff coverage, and outreach was identified as the main service development opportunity.Conclusion – The adaptation of an existing questionnaire provided a clear assessment of the effectiveness of a primary health care information service to a broad spectrum of users. Respondents identified what they valued about the service and how it could be improved.

  3. Adaptation of Impact Questions from an Existing Toolkit Provided Clear Assessment of Valued Service Elements and Desirable Service Improvements in a Primary Health Care Library and Information Service. A Review of: Urquhart, C., Thomas, R., Ovens, J., Lucking, W., & Villa, J. (2010). Planning changes to health library services on the basis of impact assessment. Health Information and Libraries Journal, 27(4), 277-285. doi: 10.1111/j.1471-1842.2010.00900.x


    Kate Kelly


    Objective – To provide an action plan for the Knowledge, Resource and Information Service (KRIS) based on an impact assessment of current services, satisfaction with current services, and views on desirable improvements to service and service delivery.Design – Questionnaire for KRIS service users and interviews with KRIS staff.Setting – Two locations served by KRIS in the north and south of Bristol City in the UK – one a health promotion service and one a National Health Service (NHS) teachin...

  4. 10 CFR 150.31 - Requirements for Agreement State regulation of byproduct material. (United States)


    ... REGULATORY AUTHORITY IN AGREEMENT STATES AND IN OFFSHORE WATERS UNDER SECTION 274 Enforcement § 150.31... long term impacts, including decommissioning, decontamination, and reclamation impacts associated...

  5. EST Table: FY741742 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available FY741742 E_FL_famL_16A21_F_0 11/11/04 95 %/274 aa ref|NP_001037126.1| ribosomal pro...tein L3 [Bombyx mori] gb|AAV34812.1| ribosomal protein L3 [Bombyx mori] 11/11/04 72 %/274 aa FBpp0176673|Dpe...PA Protein|2R:39456604:39459567:1|gene:AGAP003556 11/11/04 78 %/274 aa gnl|Amel|GB15261-PA 11/11/04 78 %/274

  6. Paul Scherrer Institute Scientific Report 1999. Volume I: Particles and Matter

    Energy Technology Data Exchange (ETDEWEB)

    Gobrecht, J.; Gaeggeler, H.; Herlach, D.; Junker, K.; Kettle, P.-R.; Kubik, P.; Zehnder, A. [eds.


    lthough originally planned for fundamental research in nuclear physics, the particle beams of pions, muons, protons and neutrons are now used in a large variety of disciplines in both natural science and medicine. The beams at PSI have the world's highest intensities and therefore allow certain experiments to be performed, which would not be possible elsewhere. The highlight of research this year was the first-ever determination of the chemical properties of the superheavy element {sup 107} Bohrium. This was undertaken, by an international team led by H. Gaeggeler of PSI's Laboratory for Radiochemistry. Bohrium was produced by bombarding a Berkelium target with Neon ions from the Injector I cyclotron and six atoms were detected after having passed through an online gas chromatography device. At the Laboratory for Particle Physics the focus has shifted from nuclear physics to elementary particle physics with about a fifty-fifty split between investigations of rare processes or particle decays using the high intensity muon, pion and recently also polarized neutron beams of PSI, and research at the highest energy frontier at CERN (Geneva) and DESY (Hamburg). Important space instrumentation has been contributed by the Laboratory for Astrophysics to the European Space Agency and NASA satellite programmes. The Laboratory for Micro and Nanotechnology continued to focus on research into molecular nanotechnology and SiGeC nanostructures, the latter with the aim of producing silicon based optoelectronics. Progress in 1999 in these topical areas is described in this report. A list of scientific publications in 1999 is also provided.

  7. Drug: D06260 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D06260 Drug Tybamate (USP/INN); Solacen (TN) C13H26N2O4 274.1893 274.3565 Tranquilizer [minor] CAS: 4268-36-4 PubChem: 47207918 LigandBox: D06260 NIKKAJI: J8.698C ATOM 19 1 C1a C 8

  8. Protein (Viridiplantae): 255551869 [PGDBj - Ortholog DB

    Lifescience Database Archive (English)

    Full Text Available 24:274 3398:274 71240:556 91827:556 71275:1304 91835:679 3646:4388 3977:2966 235629:2966 235880:2966 3987:2966 3988:2966 Protein peng...uin, putative Ricinus communis MAAKKQEKKRKQNSDAKNVTDSLPSKKPKLNEKFKKPFDPSKKLNDKSKLGQ

  9. Cholinesterase Structure: Identification of Residues and Domains Affecting Organophosphate Inhibition and Catalysis (United States)


    269-274, 1997. ISSN 0006-2952/97/$17.00 + 0.00 "© 1997 Elsevier Science Inc . All rights reserved. PII S0006-2952(97)00180-9 ELSEVIER Mutant...potential candidates for pre- or post-exposure treatment for OP toxicity. BIOCHEM PHARMACOL 54;2:269-274, 1997. © 1997 Elsevier Science Inc . KEY WORDS

  10. 75 FR 28103 - Indian Child Welfare Act; Designated Tribal Agents for Service of Notice (United States)


    ...: (907) 766- 2845; E-mail: . Chinik Eskimo Community (Golovin), Joyce Fagerstrom, Tribal Family Coordinator, P.O. Box 62019, Golovin, AK 99762; Phone: (907) 779-3489; Fax: (907) 779-2000..., Alaska 99503; Phone: (907) 274- 2195; Fax: (907) 274-2196; E-mail: . Golovin (see...

  11. 76 FR 30437 - Indian Child Welfare Act; Designated Tribal Agents for Service of Notice (United States)


    ...: (907) 766-2845; E-mail: . Chinik Eskimo Community (Golovin), Sherri Lewis, Tribal Family Coordinator, P.O. Box 62019, Golovin, AK 99762; Phone: (907) 779-3489; Fax: (907) 779-2000; E-mail... 99503; Phone: (907) 274- 2195; Fax: (907) 274-2196; E-mail: . Golovin (see Chinik...

  12. 77 FR 45815 - Indian Child Welfare Act; Designated Tribal Agents for Service of Notice (United States)


    ...: Chinik Eskimo Community (Golovin), Sherri Lewis, Tribal Family Coordinator, P.O. Box 62019, Golovin, AK 99762; Phone: (907) 779-3489; Fax: (907) 779-2000; Email: (907) 274- 2195; Fax: (907) 274-2196; Email: Golovin (see Chinik Eskimo Community)...

  13. EST Table: FS914277 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available FS914277 E_FL_fufe_31M22_F_0 10/09/28 37 %/274 aa ref|XP_969699.1| PREDICTED: similar to fuzzy.../274 aa gi|91081315|ref|XP_969699.1| PREDICTED: similar to fuzzy CG13396-PA [Tribolium castaneum] CK514734 fufe ...

  14. The Serratia gene cluster encoding biosynthesis of the red antibiotic, prodigiosin, shows species- and strain-dependent genome context variation

    DEFF Research Database (Denmark)

    Harris, Abigail K P; Williamson, Neil R; Slater, Holly;


    The prodigiosin biosynthesis gene cluster (pig cluster) from two strains of Serratia (S. marcescens ATCC 274 and Serratia sp. ATCC 39006) has been cloned, sequenced and expressed in heterologous hosts. Sequence analysis of the respective pig clusters revealed 14 ORFs in S. marcescens ATCC 274 and...

  15. 2011 Montana Youth Risk Behavior Survey: Alternative Schools (United States)

    Montana Office of Public Instruction, 2011


    This report presents the 2011 Montana Youth Risk Behavior alternative school student frequency distributions. These frequency distributions are based upon surveys with 274 alternative school students in Montana during February of 2011. Frequency distributions may not total 274 due to nonresponse and percents may not total 100 percent due to…

  16. Experiment list: SRX573052 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available wild-type Hela Cells || antibody=anti-INTS11 rabbit polyclonal (Bethyl, A301-274A...) || source=IP with Ab anti-INTS11 rabbit polyclonal (Bethyl, A301-274A) || sample type=ChIP-seq http://dbar

  17. Experiment list: SRX573051 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ld-type Hela Cells || antibody=anti-INTS11 rabbit polyclonal (Bethyl, A301-274A) ...|| source=IP with Ab anti-INTS11 rabbit polyclonal (Bethyl, A301-274A) || sample type=ChIP-seq http://dbarch

  18. Experiment list: SRX573053 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ild-type Hela Cells || antibody=anti-INTS11 rabbit polyclonal (Bethyl, A301-274A)... || source=IP with Ab anti-INTS11 rabbit polyclonal (Bethyl, A301-274A) || sample type=ChIP-seq http://dbarc

  19. Experiment list: SRX573054 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available wild-type Hela Cells || antibody=anti-INTS11 rabbit polyclonal (Bethyl, A301-274A...) || source=IP with Ab anti-INTS11 rabbit polyclonal (Bethyl, A301-274A) || sample type=ChIP-seq http://dbar

  20. 26 CFR 301.7701(b)-3 - Days of presence in the United States that are excluded for purposes of section 7701(b). (United States)


    ... compete in a charitable sports event described in section 274(l)(1)(B). For purposes of computing the days... sports event described in section 274(l)(1)(B) shall be excluded. Thus, days on which the individual is... on that date as a result of the injuries suffered in the accident. B recovered from the injuries...

  1. 78 FR 52219 - State of Georgia Relinquishment of Sealed Source and Device Evaluation and Approval Authority (United States)


    ...-415- 7135; email: . SUPPLEMENTARY INFORMATION: Section 274b. of the Atomic Energy... and activities. On December 15, 1969, Georgia entered into a Section 274b. Agreement with the Atomic... special nuclear material in quantities not sufficient to form a critical mass. Currently, the State...

  2. 75 FR 41123 - Fisheries of the Exclusive Economic Zone Off Alaska; Bering Sea Subarea (United States)


    ... (27.4 m) lengths. By working with the nonpelagic trawl fishing industry, the AFSC determined that... trawling for the purpose of studying the effects of nonpelagic trawling on bottom habitat. The SMIHCA...

  3. FAA Air Traffic Activity: Fiscal Year 1988 (United States)


    186160481 132857 1396 SANTA MARIA PUBLIC (SMX) N ITINERANT OPERATIONS...195815 61580 101949 27321 4965 SAN JUAN ISLA GRANDE (SIG) L ITINERANT OPERATIONS...194 132740 SANTA MARIA PUBLIC ...................................... CA N 274 88663 OSHKOSH WITTMAN FIELD ............................ WI N 195 132453

  4. 76 FR 58138 - Defense Federal Acquisition Regulation Supplement (DFARS); Alternative Line Item Structure (DFARS... (United States)


    ... regulatory approaches that maximize net benefits (including potential economic, environmental, public health...). (C) Use the clause at 252.211-7003, Item Identification and Valuation, as prescribed in 211.274-4....

  5. 76 FR 21847 - Defense Federal Acquisition Regulation Supplement (DFARS), Alternative Line-Item Structure (DFARS... (United States)


    ... economic, environmental, public health and safety effects, distributive impacts, and equity). Executive... Identification and Valuation, as prescribed in 211.274-4. (D) Use the clause at 252.211-7006, Radio...

  6. Incidence of PTLD in pediatric renal transplant recipients receiving basiliximab, calcineurin inhibitor, sirolimus and steroids

    NARCIS (Netherlands)

    McDonald, R. A.; Smith, J. M.; Ho, M.; Lindblad, R.; Ikle, D.; Grimm, P.; Wyatt, R.; Arar, M.; Liereman, D.; Bridges, N.; Harmon, W.


    Pediatric renal transplant recipients were enrolled in a multicenter, randomized, double-blind trial of steroid withdrawal. Subjects received basiliximab, calcineurin inhibitor, sirolimus and steroids. Of 274 subjects enrolled, 19 (6.9%) subjects developed posttransplant lymphoproliferative disorder

  7. 75 FR 27544 - National Institute on Disability and Rehabilitation Research (NIDRR)-Disability and... (United States)


    ...- Based Practice. Psychiatric Rehabilitation Journal, 27(4), 345-359. Canadian Institutes of Health... National Institute on Disability and Rehabilitation Research (NIDRR)--Disability and Rehabilitation Research Projects and Centers Program--Disability Rehabilitation Research Project (DRRP)--Center...

  8. Snowy plover survey: Great Salt Lake, UT: Summary report 2007 (United States)

    US Fish and Wildlife Service, Department of the Interior — The snowy plover survey was conducted in the Great Salt Lake ecosystem from 7 May - 7 June 2007. A total of 274 clusters were surveyed and 659 birds counted. The...

  9. 76 FR 76184 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance (United States)


    ...,274 OmniVision Technologies Boulder, CO July 8, 2010. Inc., Optics Division. 80,311 Verizon Business... Scranton, PA July 27, 2010. America Corporation, Global Trade Operations Import Letter, etc....

  10. AcEST: DK945607 [AcEST

    Lifescience Database Archive (English)

    Full Text Available =Vitis... 33 5.6 tr|Q24748|Q24748_DROVI Mobile elemnt gypsy, complete OS=Drosophi...t: 274 QYAPYYNMPAQTPHAPYMSSHTGHASFNVAVAAAQSSHMQFHGLYHS 320 >tr|Q24748|Q24748_DROVI Mobile elemnt gypsy, comp

  11. 78 FR 76293 - Combined Notice of Filings (United States)


    ...: RP14-274-000. Applicants: NGO Transmission, Inc. Description: NGO Transmission, Inc. submits tariff filing per 154.204: NGO Transmission, Inc.--Negotiated Rate Filing to be effective 1/1/2014. Filed...

  12. 76 FR 62819 - Notice of Intent To Amend the Resource Management Plan for the San Luis Resource Area, Colorado... (United States)


    ... Lucero, Interdisciplinary Team Lead, (719) 274-6327; see address above; e-mail . Persons... interdisciplinary approach to develop the RMP amendment in order to consider the resource issues and...

  13. 78 FR 26727 - Pension Benefit Statements (United States)


    ... Capital Accumulation: A New Answer, American Economic Review 92(2): 274- 279 (May 2002) and Jeffrey R... Psychological Review 91 (1993). Would a more conservative safe harbor assumption (e.g., risk-free return...

  14. The comparative effect of an addition of a surface term to the Woods-Saxon potential on the thermodynamics of a nucleon

    CERN Document Server

    Lütfüoğlu, B C


    In this study, we reveal the difference between Woods-Saxon (WS) and Generalized Symmetric Woods-Saxon (GSWS) potentials in order to describe the physical properties of a nucleon, by means of solving Schr\\"odinger equation for the two potentials. The additional term squeezes the WS potential well, which leads an upward shift in the spectrum, resulting in a more realistic picture. The resulting GSWS potential does not merely accommodate extra quasi bound states, but also has modified bound state spectrum. As an application, we apply the formalism to a real problem, an $\\alpha$ particle confined in Bohrium-$270$ nucleus. The thermodynamic functions Helmholtz energy, entropy, internal energy, specific heat of the system are calculated and compared in both wells. The internal energy and the specific heat capacity increase, as a result of upward shift in the spectrum. The shift of the Helmholtz free energy is a direct consequence of the shift of the spectrum. The entropy decreases because of a decrement in the num...

  15. Antipeptide antibodies that can distinguish specific subunit polypeptides of glutamine synthetase from bean (Phaseolus vulgaris L.) (United States)

    Cai, X.; Henry, R. L.; Takemoto, L. J.; Guikema, J. A.; Wong, P. P.; Spooner, B. S. (Principal Investigator)


    The amino acid sequences of the beta and gamma subunit polypeptides of glutamine synthetase from bean (Phaseolus vulgaris L.) root nodules are very similar. However, there are small regions within the sequences that are significantly different between the two polypeptides. The sequences between amino acids 2 and 9 and between 264 and 274 are examples. Three peptides (gamma 2-9, gamma 264-274, and beta 264-274) corresponding to these sequences were synthesized. Antibodies against these peptides were raised in rabbits and purified with corresponding peptide-Sepharose affinity chromatography. Western blot analysis of polyacrylamide gel electrophoresis of bean nodule proteins demonstrated that the anti-beta 264-274 antibodies reacted specifically with the beta polypeptide and the anti-gamma 264-274 and anti-gamma 2-9 antibodies reacted specifically with the gamma polypeptide of the native and denatured glutamine synthetase. These results showed the feasibility of using synthetic peptides in developing antibodies that are capable of distinguishing proteins with similar primary structures.

  16. Modeling Vessel-Generated Currents and Bed Shear Stresses (United States)


    Vessel 1, the fraction of the draft applied over PBOW is 0.95. CSTR 1 0.95 For Vessel 1, the fraction of the draft applied over PSTR is 0.95...vessel draft is 0.95. CSTR 2 0.95 For Vessel 2, the ratio of the stern length to the vessel length is 0.95. PROP 2 1 2.74 6 52 5 The propellers...PBOW 1 0.1 PSTR 1 0.1 CBOW 1 0.95 CSTR 1 0.95 PROP 1 2 2.74 6 52.5 SDEF 1 1 0 -3080.0 -1.5 2.9 FDEF 2 1 -6955.0 -1.5 2.9 DRFT 2 2.74 BLEN 2

  17. Pressure dependence of BaNi2As2

    Energy Technology Data Exchange (ETDEWEB)

    Ronning, Filip [Los Alamos National Laboratory; Park, Tuscon [Los Alamos National Laboratory; Bauer, Eric D [Los Alamos National Laboratory; Thompson, Joe D [Los Alamos National Laboratory


    We report results from resistivity measurements of BaNi{sub 2}As{sub 2} up to 27.4 kbar of pressure. We find the structural transition at 130 K is broadened slightly with increasing pressure. There is also minimal influence on the superconducting transition, where the resistive onset increases from 2 to 3 K, but the temperature at which zero resistance is obtained is unchanged up to 27.4 kbar. This behavior is in contrast to that observed in the Fe-based systems as well as in LaNiPO and LaNiAsO.

  18. An Evaluation of Compressed Work Schedules and Their Impact on Electricity Use (United States)


    chillers cool water to 46 degrees Fahrenheit ; the water flows through coils in the air handlers. Thermostat settings in individual rooms dictate demand...will temporarily reduce the load; however, the increased energy necessary to return the water to 46 degrees Fahrenheit will offset some, if not all, of...290 361 431 285 331 447 273 303 438 21:30 290 353 424 289 358 424 280 330 451 274 301 428 22:00 290 352 417 289 356 422 280 329 439 274 300 425 22:30

  19. CTC Sentinel. Volume 7, Issue 10, October 2014 (United States)


    objective was to 7 United States of America v Liberty Reserve S.A, No. USA -33s-274 (Ed. 9-25-58), United States District Court, Southern District of...Ross William Ulbricht, USA - 33s-274 (Ed. 9-25-58), United States District Court, Southern District of New York, February 4, 2014. 12 Tor is free...20 These discussions were posted to the Shumukh al- Islam Network on April 29, 2013. oCToBeR 2014 . VoL 7. IssUE 10 “Cryptography is a never- ending

  20. The Role of Intuition in the Decision-Making Processes of United States Air Force Field Grade Officers (United States)


    INTJ J I ISTP ISFP INFP INTP P E ESTP ESFP ENFP ENTP P E ESTJ ESFJ ENFJ ENTJ J T P F T Value of the MBTI. The MBTI has been used extensively since its...6.85 6.44 INFJ 2.74 3.41 INFP 6.85 6.06 ENFP 10.96 8.71 ENFJ 1.37 2.65 INTJ 6.85 3.03 INTP 0 1.52 ENTP 5.48 5.30 ENTJ 2.74 4.92 69 Intuition and the

  1. Properties of Group Five and Group Seven transactinium elements

    Energy Technology Data Exchange (ETDEWEB)

    Wilk, Philip A.


    The detection and positive identification of the short-lived, low cross section isotopes used in the chemical studies of the heaviest elements are usually accomplished by measuring their alpha-decay, thus the nuclear properties of the heaviest elements must be examined simultaneously with their chemical properties. The isotopes 224 Pa and 266,267 Bh have been studied extensively as an integral part of the investigation of the heaviest members of the groups five and seven of the periodic table. The half-life of 224 Pa was determined to be 855 plus/minus19 ms by measuring its alpha-decay using our rotating wheel, solid state detector system at the Lawrence Berkeley National Laboratory 88-Inch Cyclotron. Protactinium was produced by bombardment of a bismuth target. New neutron rich isotopes, 267 Bh and 266 Bh, were produced in bombardments of a 249 Bk target and their decay was observed using the rotating wheel system. The 266 Bh that was produced decays with a half-life of approximately 1 s by emission of alpha particles with an average energy of 9.25 plus/minus 0.03 MeV. 267 Bh was observed to decay with a 17 s half-life by emission of alpha-particles with an average energy of 8.83 plus/minus 0.03 MeV. The chemical behavior of hafnium, Ha (element 105) was investigated using the fast on-line continuous liquid extraction and detection system SISAK-LISSY. Hafnium was not observed in this experiment following transport and extraction. Protactinium was used as on-line test of the apparatus to determine the experimental efficiency of the entire system. Unfortunately, the amount of protactinium observed after the extraction, compared to the amount produced, was extremely small, only 2.5%. The extraction of the protactinium isotope indicated the efficiency of the apparatus was too low to observe the extraction of hafnium. The chemical behavior of oxychloride compounds of bohrium was investigated by isothermal gas adsorption chromatography in a quartz column at 180, 150

  2. An experimental paradigm opening the world of superheavy elements (United States)

    Armbruster, P.; Münzenberg, Gottfried


    The history of the discovery of the six elements Z = 107 ∓ 112, bohrium, hassium, meitnerium, darmstadtium, roentgenium, and copernicium goes back to the early 1960s. An experimental method to separate and identify rare nuclear reaction products, the recoil separation, was developed and optimised for beams of fission products at European research reactors. Chemical elements beyond the then first transactinides ( Z = 104), which owe their stability to the internal structure of atomic nuclei, were predicted theoretically. A big brother of the shell-stabilised nucleus 208Pb, a spherical magic nucleus at Z = 114∓126 and N = 184, might reach lifetimes long enough to be detected. In the seventies, hunting superheavy elements (SHE) was on the agenda of nuclear chemistry. Could the Periodic Table of Elements be extended to Z = 120, and is the order of electrons in the atom still following the laws established for lighter elements? In Germany, the heavy ion accelerator (UNILAC) was built by Christoph Schmelzer and his team at GSI, Darmstadt. SHE and UNILAC met the recoil separators in 1968, and SHIP (Separator for Heavy Ion reaction Products) was ready together with the first UNILAC-beams in 1976. Recoil separation is orders of magnitude more sensitive, selective, and faster than earlier methods used to synthesise elements up to seaborgium, Z = 106. The experimental paradigm we introduced opened the world of SHEs. At SHIP we discovered and investigated the elements Z = 107∓112 in the years 1980-2000. Our laboratory was the world champion during this time. Today our experimental method is used worldwide in the search for SHEs, but the leadership went to the Russian laboratory JINR in Dubna, which extended the Periodic Table by 6 more elements to Z = 118, the candidate for the next rare gas.

  3. Synthesis of the heaviest nuclei in cold fusion reactions (United States)

    Münzenberg, G.; Morita, K.


    Cold fusion of heavy ions paved the way to superheavy elements. It was proposed by Yu.Ts. Oganessian more than forty years ago in 1974 [1,2]. First experiments were carried out at JINR Dubna, starting with the reaction 40Ar + 208Pb → 248Fm* where several hundreds to thousand atoms were produced on one day. The large production rate indicating an enhancement of the fusion cross section, especially for the evaporation of two or three neutrons, proved the concept of cold-fusion with the use of the doubly magic nucleus 208Pb as a target. The Dubna experiments were extended to the transactinide region beyond rutherfordium. The breakthrough came with the separation in-flight. Two different approaches were used: kinematic separation with the velocity filter SHIP [3] at GSI Darmstadt, and with the gasfilled separator GARIS [4,5] at RIKEN. With SHIP the concept of cold fusion of massive nuclear systems was convincingly confirmed by the observation of the one-neutron evaporation channel in the production of 247Rf in an irradiation of 208Pb with 50Ti [6] in 1981 which opened the way to the transactinide region. At SHIP the elements bohrium (107) to copernicium (112) were discovered [7]. A new closed shell region around hassium was found. The RIKEN experiments started in 2002. They confirmed the GSI results and in addition improved the data on structure and production of elements hassium to copernicium significantly. The heaviest element ever created in a cold fusion reaction, Z = 113, was observed at GARIS [8,9].

  4. Use of osteoplastic material to guide bone tissue regeneration deffect. (United States)

    Machavariani, A; Mazmishvili, K; Grdzelidze, T; Menabde, G; Amiranashvili, I


    The goal of research was study of restoration processes in jaw-teeth bone defects by application of osteoplastic materials in the experiment. The experiment was performed over 32 white (6-12 month old) rats; the animals were divided into 2 groups; 16 animals were enrolled in the first group; the section was performed in the edge of lower jaw; the lower jaw body was revealed. Under the effect of the dental drilling machine and the # 1 cooling mean by the fissure bohrium (distilled water) the defect of the dimension of 2x2 mm was created; the defect was washed by 0/9% saline to remove the bone sawdust; the wound was sutured tightly, in layers. The second group of the experiment was staffed with 16 animals (main group); the similar bone defect of the size 2 x 2mm was created on the rat's jaw's body. After washing of modeled defect we inserted osteopathic materials PORESORB-TCP crystals with the size of 0,6-1.0 mm the wound was sutured tightly, in layers. After the 3-rd, 15-th, 30-th and 90-th days from the date of operation there was performed X-ray and morphological examination over the animals in the control as well as the main group. The analysis of the examination performed over the experimental materials showed that in the control group in samples taken at 90th day the defects were not completely restored. In the test group in samples taken at 90th day reparative regeneration is confirmed. This is stimulated by the factor that within the main group's animals the defect regeneration process is supported with the osteoplastic material PORESORB-TCP.

  5. 78 FR 70368 - Self-Regulatory Organizations; Chicago Mercantile Exchange Inc.; Notice of Filing and Immediate... (United States)


    ....A. Regarding Timing of Determination of the Spot Exchange Rate of Chilean Peso per United States....02.A. regarding cash settlement of Cleared OTC USD/CLP Spot, Forwards and Swaps Contracts. II. Self... error in the current rule text of CME Rule 274H.02.A. regarding Cash Settlement of Cleared OTC...

  6. 10 CFR 150.11 - Critical mass. (United States)


    ... 10 Energy 2 2010-01-01 2010-01-01 false Critical mass. 150.11 Section 150.11 Energy NUCLEAR... OFFSHORE WATERS UNDER SECTION 274 Exemptions in Agreement States § 150.11 Critical mass. (a) For the purposes of this part, special nuclear material in quantities not sufficient to form a critical mass...

  7. Furin proteolytically processes the heparin-binding region of extracellular superoxide dismutase

    DEFF Research Database (Denmark)

    Bowler, Russell P; Nicks, Mike; Olsen, Dorte Aa


    . (1999) J. Biol. Chem. 274, 14818-14822). By using mammalian cell lines, we have now determined that removal of the heparin-binding region occurs after passage through the Golgi network but before being secreted into the extracellular space. Specific protease inhibitors and overexpression...

  8. An Epithelial-Derived, Integral Membrane, Kunitz-Type Serine Protease Inhibitor in Breast Cancer (United States)


    an epithelial membrane serine protease. J Biol Chein 275: 36720-36725, 2000. prevents15. Lin CY, Anders J, Johnson M, and Dickson RB. Purification and...functions properly, thus trypsin-like activity. J Biol Chein 274: 18231--18236, 1999. 0 avoiding harmful effects. 17. Lin CY, Wang JK, Torri J, Dou L, Sang

  9. Screening for Small Molecules That Disrupt IAP-Caspases Binding to Activate Caspases and Induce Apoptosis in Breast Cancers (United States)


    Zou H and Fesik SW. (2004). Yuan J. (2005). Science, 307, 935-939. J. Med Chein ., 47, 4417-4426. Cao C, Mu Y, Hallahan DE and Lu B. (2004). Oncogene...Schuler M, Echeverri F and Green DR. (1999). Harran PG. (2004). Science, 305, 1471-1474. J. Biol. Chein ., 274, 30651-30656. Lima RT, Martins LM, Guimaraes

  10. Lexical Development in Korean: Vocabulary Size, Lexical Composition, and Late Talking (United States)

    Rescorla, Leslie; Lee, Youn Mi Cathy; Oh, Kyung Ja; Kim, Young Ah


    Purpose: In this study, the authors aimed to compare vocabulary size, lexical composition, and late talking in large samples of Korean and U.S. children ages 18-35 months. Method: Data for 2,191 Korean children (211 children recruited "offline" through preschools, and 1,980 recruited "online" via the Internet) and 274 U.S.…

  11. An Analysis of the Relationship between Organizational Communication and Organizational Cynicism According to Teachers' Perceptions in Turkey (United States)

    Ayik, Ahmet


    In this study, the relations between organizational communication and organizational cynicism have been analyzed. The sample of the study consists of 274 teachers working in state secondary schools in Palandöken County of Erzurum, in 2013-2014 academic year. "Organizational Cynicism Scale" and "Organizational Communication…

  12. Attachment Style, Social Support, and Coping as Psychosocial Correlates of Happiness in Persons with Spinal Cord Injuries (United States)

    Wilson, Lisa; Catalano, Denise; Sung, Connie; Phillips, Brian; Chou, Chih-Chin; Chan, Jacob Yui Chung; Chan, Fong


    Objective: To examine the roles of attachment, social support, and coping as psychosocial correlates in predicting happiness in people with spinal cord injuries. Design: Quantitative descriptive research design using multiple regression and correlation techniques. Participants: 274 individuals with spinal cord injuries. Outcome Measures: Happiness…


    NARCIS (Netherlands)



    A total of 732 cases of omphalocele and 274 cases of gastroschisis was registered in 21 regional registers in Europe (EUROCAT registers) during the period 1980-1990. The total prevalence rates were 2.52 pes 10,000 for omphalocele and 0.94 per 10,000 for gastroschisis. There was significant heterogen

  14. Language Learning Strategies of Language e-Learners in Turkey (United States)

    Solak, Ekrem; Cakir, Recep


    The purpose of this study was to determine the use of language learning strategies of e-learners and to understand whether there were any correlations between language learning strategies and academic achievement. Participants of the study were 274?e-learners, 132 males and 142 females, enrolled in an e-learning program from various majors and…

  15. Metric Selection for Ecosystem Restoration (United States)


    Ecological conceptual models: A framework and case study on ecosystem management for South Florida sustainability. The Science of the Total Environment 274...assessment: Review of qualitative and quantitative approaches. Science of the Total Environment 407: 5199-5205. Linkov, I., and E. Moberg. 2011

  16. Transcriptional Regulation of BRCA1 (United States)


    Ramos , L., Villasenor, M. R., Anders, K. H., Press, M. F., Clarke, K., Karlan, B., Chen, J. J., Scully, R., Livingston, D., Zuch, R. H., Kanter, M. H...Chem 274(44), 3 1297-304 22. Thakur, S., Lin, H. C., Tseng, W. T., Kumar, S., Bravo , R., Foss, F., Gelinas, C., and Rabson, A. B. (1994) Oncogene 9(8

  17. The Connor-Davidson Resilience Scale as a Positive Psychology Measure for People with Spinal Cord Injuries (United States)

    Fujikawa, Mayu; Lee, Eun-Jeong; Chan, Fong; Catalano, Denise; Hunter, Celeste; Bengtson, Kevin; Rahimi, Maryam


    The main objective of this study is to evaluate the measurement structure of the Connor-Davidson Resilience Scale (CD-RISC) as a positive psychology measure for people with spinal cord injuries (SCIs) using confirmatory factor analysis. The participants consisted of 274 Canadians with SCI living in the community. The result indicated that the…

  18. Burnout and Competency Development in Pre-Service Teacher Training (United States)

    Rodríguez-Hidalgo, Antonio J.; Calmaestra, Juan; Dios, Irene


    Introduction: The burnout syndrome negatively affects the students' academic performance. The relation between academic burnout and the self-perception of skills in initial teacher training is subjected to analysis. Method: A sample of 274 students (average age = 20,61 years old) from the Bachelor Degree in Early Childhood Education and the…

  19. Dicty_cDB: VSC263 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available . 278 1e-73 BT078708_1( BT078708 |pid:none) Lepeophtheirus salmonis Pacific fo... 274 2e-72 FJ376460_1( FJ376460 |pid:none) Spea hamm...ondii ribosomal protein L... 273 2e-72 ( P41116 ) RecName: Full=60S ribosomal prote

  20. Kahe keelemehe regivärsiluulest / Ruth Mirov

    Index Scriptorium Estoniae

    Mirov, Ruth, 1928-


    Ilmunud ka kogumikus: Mirov, Ruth. Sõnast sõnasse : valik artikleid ja retsensioone. Tallinn ; Tartu : Eesti Keele Sihtasutus, 2002, lk. 261-274. Rahvaluulekogumikud: Aavik, Johannes. Valik rahvalaule. Tartu : Istandik, 1919; Saarbek, Albert [=Andrus Saareste]. Valitud eesti rahavalaulud koolidele. Tallinn : Rahvaülikool, 1919

  1. An Analysis of the First Fifteen Years of the Department of Defense Framework for Unmanned Ground Systems (United States)


    270  E.  THE DARPA INTERVENTION ................................................................274  F.  SUMMARY OF ANALYSIS...28  Table 4.  Funding Agreement between DARPA and TWP ($M; from DOD, 1991) .....30  Table 5.  Requirements Articulation 1992 UGV Master...Kit CRS Common Robotic System CRS Congressional Research Service CTD Concept and Technology Demonstrations DARPA Defense Advanced Research

  2. Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans

    DEFF Research Database (Denmark)

    Amin Al Olama, Ali; Dadaev, Tokhir; Hazelett, Dennis J


    Genome-wide association studies (GWAS) have identified numerous common prostate cancer (PrCa) susceptibility loci. We have fine-mapped 64 GWAS regions known at the conclusion of the iCOGS study using large-scale genotyping and imputation in 25 723 PrCa cases and 26 274 controls of European ancest...

  3. Revision of the Lauraceae III. The genera Aiouea, Systemonodaphne, Urbanodendron, Mezilaurus; additions and corrections to Licaria and Cryptocarya

    NARCIS (Netherlands)

    Kostermans, A.J.G.H.


    Aiouea Aublet, Hist. Guian. I (1775), p. 310; III, t. 120; Scopoli, Introductio Hist. nat. (Pragae 1777), p. 107, n. 277; Lamarck, Encyclop. méthod. I (1783), p. 72 (Ajúvea); Poiret, Encycl., Suppl. I (1890), p. 274, III (1893), p. 317; Illustrat. Genr. II, p. 395 et 367, t. 360; Jussieu, Genera (17

  4. Prevalence of osteoporosis and factors associated with osteoporosis in women above 40 years in the Northern Part of Saudi Arabia

    Directory of Open Access Journals (Sweden)

    Anitha Oommen


    Conclusion: Prevalence of osteopenia is higher than osteoporosis in the Saudi women above 40 years in the Northern part of Saudi Arabia. The major cause of low BMD is lack of exercise even though there is a high prevalence of Vitamin D deficiency. [Int J Res Med Sci 2014; 2(1.000: 274-278

  5. Do Physical and Relational Aggression Explain Adolescents' Friendship Selection? The Competing Roles of Network Characteristics, Gender, and Social Status

    NARCIS (Netherlands)

    Dijkstra, Jan Kornelis; Berger, Christian; Lindenberg, Siegwart


    The role of physical and relational aggression in adolescents' friendship selection was examined in a longitudinal sample of 274 Chilean students from 5th and 6th grade followed over 1 year. Longitudinal social network modeling (SIENA) was used to study selection processes for aggression while influ

  6. Organisational age cultures : The interplay of chief executive officers age and attitudes toward younger and older employees

    NARCIS (Netherlands)

    Zacher, Hannes; Gielnik, Michael M.


    This article investigates the interactive effects of chief executive officer (CEO) age and CEO attitudes toward younger and older employees on organisational age cultures. Data was collected from 66 CEOs of small and medium-sized businesses and 274 employees. Results were consistent with expectation

  7. Stable Hydrogen and Oxygen Isotope Ratios for Selected Sites of the U.S. Geological Survey’s NASQAN and Benchmark Surface-Water Networks (United States)


    274 Ohio 03159510 Hocking River Below Athens .................................................................................275...369 12039300 North Fork Quinault River Near Amanda Park...Kanawha River At Palestine WV 54 N 39.05972 81.3903 1515 05030203 585.51 03159510 Hocking River Below Athens OH 39 N 39.32749 82.0050 957 05030204

  8. Gclust Server: 44443 [Gclust Server

    Lifescience Database Archive (English)

    Full Text Available 44443 ATH_AT4G08460_15236507 Cluster Sequences Related Sequences(37) 274 unknown pr...otein 2 1.00e-45 28.57 0.0 0.0 0.0 0.0 0.0 Show 44443 Cluster ID 44443 Sequence ID ATH_AT4G08460_15236507 Li

  9. The Study of Relationship between Organizational Culture and Organizational Belonging in Employees of Varamin County Office of Education (United States)

    Tabatabaee, Seyed Mahmoud; Koohi, Amirhasan; Ghandali, Abbas; Tajik, Tayebeh


    The purpose of the present research is to study the relationship between organizational culture and organizational belonging among employees of Varamin County ministry of education. This is a descriptive-survey study. The statistical population is consisted of all 274 official and contract employees of ministry of education in Varamin County of…

  10. An Examination of Black Science Teacher Educators' Experiences with Multicultural Education, Equity, and Social Justice (United States)

    Atwater, Mary M.; Butler, Malcolm B.; Freeman, Tonjua B.; Carlton Parsons, Eileen R.


    Diversity, multicultural education, equity, and social justice are dominant themes in cultural studies (Hall in "Cultural Dialogues in Cultural Studies." Routledge, New York, pp 261-274, 1996; Wallace 1994). Zeichner ("Studying Teacher Education: The Report of the AERA Panel on Research and Teacher Education." Lawrence Erlbaum…

  11. Crystal structures of two peptide-HLA-B*1501 complexes; structural characterization of the HLA-B62 supertype

    DEFF Research Database (Denmark)

    Roder, G; Blicher, Thomas; Justesen, Sune Frederik Lamdahl;


    of human immune responses, the structure of at least one member of each supertype should be determined. Here, the structures of two immunogenic peptide-HLA-B*1501 complexes are described. The structure of HLA-B*1501 in complex with a peptide (LEKARGSTY, corresponding to positions 274-282 in the Epstein-Barr...

  12. AcEST: BP914519 [AcEST

    Lifescience Database Archive (English)

    Full Text Available erized ORF2/4 protein OS=Torque teno virus (isolate Human/Germany/KAV/2001) GN=ORF2/4 PE=4 SV=2 Length = 274...eno virus (isolate Human/Germany/KAV/2001) GN=ORF2/3 PE=3 SV=2 Length = 265 Score = 30.8 bits (68), Expect =

  13. 76 FR 37897 - Performance of Functions; Claims for Compensation Under the Federal Employees' Compensation Act... (United States)


    ..., Office of Workers' Compensation Programs, Federal Employees' Compensation Act File, 67 FR 16826 (April 8... Office of Workers' Compensation Programs (OWCP) by Employment Standards Order No. 2-74 (39 FR 34722). The... Programs (37 FR 20533) and an Office of Federal Employees' Compensation (37 FR 22979). In 1974, these...

  14. Locomotive System

    Institute of Scientific and Technical Information of China (English)


    2008477 Diagnostic value of dystrophin in childhood and adolescent muscular disorders. ZHANG Meng(张萌), et al. Dept pathol, 1st Affili Hosp, Sun Yat-sen Univ, Guangzhou 510080.Chin J Nerv Ment Dis 2008;34(5):274-277. Objective To explore the diagnostic values of dystrophin immunohistochemical reaction in childhood and adolescent muscular disorders.

  15. The Application of Linear Prediction to Sequential Classification of Radar Target Signatures (United States)


    treated in the earlier portion of this report. However, generalization serves only to complicate the algebra and adds very little to the understanding...Wiley, New York, 1958). 9. E. A. Robinson, Statistical Communication and Detection (Hafner Publishing Company, New York, 1967), pp. 274-279. i0. J. Durbin

  16. The Efficacy of LY293558 in Blocking Seizures and Associated Morphological, and Behavioral Alterations Induced by Soman in Immature Male Rats and the Role of the M1 Muscarinic Acetylcholine Receptor in Organophosphate Induced Seizures (United States)


    the parent compound (286). Synthesized in 1944, parathion is one of the most lethal pesticides (287) and has been used as a chemical weapon in war...hippocampus to cued and contextual fear conditioning. Behavioral neuroscience 106:274-85 220. Pidoplichko VI. 1992. Ammonia and proton gated channel

  17. Burnout and Competency Development in Pre-Service Teacher Training (United States)

    Rodríguez-Hidalgo, Antonio J.; Calmaestra, Juan; Dios, Irene


    Introduction: The burnout syndrome negatively affects the students' academic performance. The relation between academic burnout and the self-perception of skills in initial teacher training is subjected to analysis. Method: A sample of 274 students (average age = 20,61 years old) from the Bachelor Degree in Early Childhood Education and the…

  18. Complete genome sequence of Lactobacillus plantarum WCFS1

    NARCIS (Netherlands)

    Kleerebezem, Michiel; Boekhorst, Jos; Kranenburg, Richard van; Molenaar, Douwe; Kuipers, Oscar P.; Leer, Rob; Tarchini, Renato; Peters, Sander A.; Sandbrink, Hans M.; Fiers, Mark W.E.J.; Stiekema, Willem; Klein Lankhorst, René M.; Bron, Peter A.; Hoffer, Sally M.; Nierop Groot, Masja N.; Kerkhoven, Robert; Vries, Maaike de; Ursing, Björn; Vos, Willem M. de; Siezen, Roland J.


    The 3,308,274-bp sequence of the chromosome of Lactobacillus plantarum strain WCFS1, a single colony isolate of strain NCIMB8826 that was originally isolated from human saliva, has been determined, and contains 3,052 predicted protein-encoding genes. Putative biological functions could be assigned t

  19. 78 FR 79567 - Supplemental Nutrition Assistance Program: Trafficking Controls and Fraud Investigations (United States)


    ...] [Page 79567] [FR Doc No: 2013-31354] DEPARTMENT OF AGRICULTURE Food and Nutrition Service 7 CFR Parts 271 and 274 RIN 0584-AE26 Supplemental Nutrition Assistance Program: Trafficking Controls and Fraud Investigations AGENCY: Food and Nutrition Service, USDA. ACTION: Final rule, Interim final rule; notice...

  20. Domain Modeling: NP_008881.2 [SAHG[Archive

    Lifescience Database Archive (English)

    Full Text Available NP_008881.2 chrX Crystal Structure of Rat Synapsin I C Domain Complexed to Ca.ATP (...Form 1) c1px2b_ chrX/NP_008881.2/NP_008881.2_holo_113-417.pdb blast 188H,225K,267V,269K,273A,274H,275S,276G,

  1. Disease: H00289 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available Bourc'his D Genetics and epigenetics of hydatidiform moles. Nat Genet 38:274-6 (2006) PMID:19309689 (gene) ...inflammatory and apoptotic pathways. Cancer NALP7 [HSA:199713] ICD-9: 630 OMIM: 231090 PMID:17204043 (gene) Slim R, Mehio A The genet...ics of hydatidiform moles: new lights on an ancient disease. Clin Genet 71:25-34 (2

  2. Compositional Verification with Abstraction, Learning, and SAT Solving (United States)


    Amla and Kenneth L. McMillan. A Hybrid of Counterexample-Based and Proof-Based Abstraction. In FMCAD, pages 260–274, 2004. 203 [13] Nina Amla and...Verification. In CAV, 2010. [91] Kenneth L. McMillan and Nina Amla . Automatic Abstraction without Coun- terexamples. In TACAS, 2003. [92] Kenneth L. McMillan

  3. Image Descriptors for Displays (United States)


    13, 274 (1969). 15. E. E. Smith and K. T. Spoehr, ’The Perception of Printea inglish," in SB. Kantowitz , ed., ihumr Information Processing: Tutorials...Processing Research," in B. Kantowitz , ed., Human Information Processing: Tutorials in Performance and Cognition (Halsted Press, New York, 1974). 26. J. J

  4. 75 FR 81831 - Supplemental Nutrition Assistance Program, Regulation Restructuring: Issuance Regulation Update... (United States)


    ... 7 CFR part 274 and was published at 75 FR 18377 on April 12, 2010. Dated: November 24, 2010. Julia... coupon issuance and EBT pilot regulations that are no longer applicable, revise regulatory language to... Food and Nutrition Service adopted as a final rule the direct final rule published at 75 FR 18377...

  5. AcEST: BP921654 [AcEST

    Lifescience Database Archive (English)

    Full Text Available r OS=Yersinia pestis GN=hmuR P... 30 7.2 sp|Q20911|CUBN_CAEEL Probable cubilin OS=Caenorhabditis elegans ......L+ E + T +Q YYS + I+ P+ + Sbjct: 274 PSSTNVMTNRSTIQRDAQLRYNIKPLDQEWLNAT-AQVYYSEVEINARPQGS 324 >sp|Q20911|CUBN_CAEEL Probable cubilin

  6. HLA-Restricted CTL That Are Specific for the Immune Checkpoint Ligand PD-L1 Occur with High Frequency in Cancer Patients

    DEFF Research Database (Denmark)

    Munir, Shamaila; Andersen, Gitte Holmen; Met, Özcan;


    PD-L1 (CD274) contributes to functional exhaustion of T cells and limits immune responses in patients with cancer. In this study, we report the identification of an human leukocyte antigen (HLA)-A2-restricted epitope from PD-L1, and we describe natural, cytolytic T-cell reactivity against PD-L1...

  7. Data of evolutionary structure change: 1A4VA-1JKBA [Confc[Archive

    Lifescience Database Archive (English)


  8. A catalogue of the Coelenterate type specimens of the Zoological Museum of Amsterdam. IV. Gorgonacea, Actiniaria, Scleractinia

    NARCIS (Netherlands)

    Soest, van R.W.M.


    This final part of the Coelenterate type catalogue lists 274 nominal types (183 Gorgonacea, 9 Actiniaria and 82 Scleractinia). Six not previously depicted types are represented by photographic illustrations of their habit. Furthermore lists are provided of schizotypes, i.e. fragments of types housed

  9. Dispersion-managed semiconductor mode-locked ring laser. (United States)

    Resan, Bojan; Archundia, Luis; Delfyett, Peter J; Alphonse, Gerard


    A novel breathing-mode external sigma-ring-cavity semiconductor mode-locked laser is developed. Intracavity pulse compression and stretching produce linearly chirped pulses with an asymmetric exponential temporal profile. External dispersion compensation reduces the pulse duration to 274 fs (within 10% of the bandwidth limit).

  10. Performance of first-trimester combined test for Down syndrome in different maternal age groups: reason for adjustments in screening policy?

    NARCIS (Netherlands)

    Engels, Martin; Heijboer, A.C.; Blankenstein, M.A.; Vugt, J.M.G. van


    OBJECTIVE: To evaluate the performance of the first-trimester combined test (FCT) in different maternal age groups and to discuss whether adjustments in screening policies should be made. METHODS: In this retrospective study data (n = 26 274) from a fetal medicine center on FCT (maternal age, fetal

  11. Adaptive and Challenged Parenting among African American Mothers: Parenting Profiles Relate to Head Start Children's Aggression and Hyperactivity (United States)

    Carpenter, Johanna L.; Mendez, Julia


    Research Findings: This study used a within-group research design and person-centered analytic methods to identify multidimensional profiles of parenting styles, parenting practices, and related emotional factors in a sample of 274 African American mothers recruited from Head Start programs in the northeastern and southeastern United States.…

  12. A Neural Network for Estimation of Aortic Pressure from the Radial Artery Pressure Pulse (United States)


    from periphery to artery: a model based study, American Journal of Physiology, 1998,274:43, pp H1386-92 [9] C. Chen, E. Nevo , B Fetics, P Pak, F, Yin, L...36. [10] B Fetics, E Nevo , C. Chen, D Kass, Parametric model derivation of transfer function for noninvasive estimation of aortic pressure by radial

  13. Influenza virus resistance to oseltamivir: what are the implications?

    NARCIS (Netherlands)

    Fleming, D.M.; Elliot, A.J.; Meijer, A.; Paget, W.J.


    Influenza caused by an oseltamivir-resistant influenza A(H1N1) virus was widespread across Europe during the 2007–08 winter. About 25% of A(H1N1) viruses tested in the European Influenza Surveillance Scheme (EISS) were resistant with an H274Y mutation in the neuraminidase glycoprotein. Early indicat

  14. New Measures of Heart-Rate Complexity: Effect of Chest Trauma and Hemorrhage (United States)


    299. 6. Goldberger AL, West BJ. Applications of nonlinear dynamics to clinical cardiology . Ann NY Acad Sci. 1987;504:195–213. 7. Buchman TG...Palazzolo JA, Estafanous FG, Murray PA. Entropy measures of heart rate variation in conscious dogs . Am J Physiol. 1998;274:H1099–H1105. 34. West BJ

  15. Assessment of the Need to Perform Life-Saving Interventions Using Comprehensive Analysis of the Electrocardiogram and Artificial Neural Networks (United States)


    physiological interpretation and clinical use. Task force of the european society of cardiology and the north american society of pacing and...rate variation in conscious dogs . Am J Physiol 274:H1099-1105, 1998. 38. Abu-Hanna A and Lucas PJ. Prognostic models in medicine. Ai and statistical

  16. Complexity, Heuristic, and Search Analysis for the Games of Crossings and Epaminondas (United States)


    second. 40 Next, leveraging heuristics from Lines of Action and the ancient Egyptian game Seega, the evaluation function was modified to take into account...Institute of Technology Air University Air Education and Training Command in Partial Fulfillment of the Requirements for the Degree of Master of...17 2.7.3 History Heuristic . . . . . . . . . . . . . . . . . . . . . . . . . . . 17 2.7.4 Transposition Tables

  17. Collaboration Practices: An Analysis Within an Army Acquisition Program Office (United States)


    decision. The analysis of the interview data provides insight into which domains were dominant at a given time, active but not dominate, and passive...255–274). Bingley, UK: Emerald Group. Hocevar, S. P., Jansen, E. & Thomas, G. F. (2012). Inter-organizational collaborative capacity (ICC

  18. Interpersonal Problem Solving, Self-Compassion and Personality Traits in University Students (United States)

    Arslan, Coskun


    The aim of this study was to investigate interpersonal problem solving in terms of self-compassion and personality traits. The participants were 570 (274 females and 296 males) who participated in the research voluntarily. The mean age of the participants was 21.54 years (between 17-32 years old) with a standard deviation of 2.68 years. Data were…

  19. 19 CFR 162.22 - Seizure of conveyances. (United States)


    ... provided for in section 594, Tariff Act of 1930 (19 U.S.C. 1594) and section 274(b)(1) of the Immigration... illegal act. The Government's remedy in such cases is limited to an action against the master or owner....

  20. Antecedents to Organizational Performance: Theoretical and Practical Implications for Aircraft Maintenance Officer Force Development (United States)


    process and going to be going into IOT &E. Learning in depth about the acquisitions process, how we fit in, and how we can make the system work...Building a learning organization. Org Dev & Trng, 6E (Iae) , 274. 26. Gefen, D., & Straub, D. (2005). A Practical Guide to Factorial Validity Using PLS


    Institute of Scientific and Technical Information of China (English)


    <正>20042213 Chen Qinghua (Department of Geology,Northwest University, Xi’an, Shaanxi); Liu Chiyang The Mathematical Representations and Their Significance of Geological Age with Milankovitch Theory (Journal of Northwest University (Natural Science Edition), ISSN1000 - 274X, CN61 -1072/N, 33(5), 2003, p. 599-602, 27 refs. )

  2. Gclust Server: 201274 [Gclust Server

    Lifescience Database Archive (English)

    Full Text Available 201274 Sme_SMc04237 Cluster Sequences - 82 hypothetical protein 1 1.00e-40 0.0 0.0 0.0 0.0 3.23 0.0 Show 201...274 Cluster ID 201274 Sequence ID Sme_SMc04237 Link to cluster sequences Cluster Se

  3. Temperature, salinity and transmissivity data from the Alpha Helix in the Arctic Ocean, 2000 - 2004 (NODC Accession 0059005) (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This is calibrated CTD downcast data from five Alpha Helix cruises: HX235, 8/1/2000 - 9/30/2000 HX250, 9/1/2001 - 9/30/2001 HX260, 6/1/2002 - 6/30/2002 HX274,...

  4. 75 FR 37707 - Administrative Process for Seizures and Forfeitures Under the Immigration and Nationality Act and... (United States)


    ... Secretary 8 CFR Part 274 19 CFR Part 162 RIN 1651-AA58 Administrative Process for Seizures and Forfeitures Under the Immigration and Nationality Act and Other Authorities AGENCY: Office of the Secretary, DHS... of the HSA, both CBP and ICE retained authority to perform asset seizures and forfeitures under...

  5. EST Table: FS835826 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available FS835826 E_FL_fmgV_49K21_R_0 10/09/28 32 %/274 aa ref|XP_001868268.1| thymus-specif...ic serine protease [Culex quinquefasciatus] gb|EDS26459.1| thymus-specific serine protease [Culex quinquefas

  6. Toward a Balanced View of Charismatic Leadership (United States)


    2004, 42-45). The contrarian view, held by societies previously dominated by charismatic dictators such as in Germany and Mexico , is a distaste for...Scientific Study of Religion 20, no. 3 (September): 274-284. 56 Burke, W. Warner 2008. Organizational Change: Theory and Practice. Thousand Oaks...

  7. GETDB: 103581 [GETDB

    Lifescience Database Archive (English)

    Full Text Available ble 1954 1 Request - muscle subset weak ubiquitous sg internal lethal P{GawB}NP0297 comment1:A, comment...NP0297 Original Comments comment1:A, comment2:74C1 Disc (Image) d1 Disc (number) 1 Embryo (Image) - Embryo (

  8. ELT Research in Turkey: A Content Analysis of Selected Features of Published Articles (United States)

    Yagiz, Oktay; Aydin, Burcu; Akdemir, Ahmet Selçuk


    This study reviews a selected sample of 274 research articles on ELT, published between 2005 and 2015 in Turkish contexts. In the study, 15 journals in ULAKBIM database and articles from national and international journals accessed according to convenience sampling method were surveyed and relevant articles were obtained. A content analysis was…

  9. Disease: H00196 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available ers of purine and pyrimidine metabolism. Mol Genet Metab 86:25-33 (2005) PMID:10066814 Ahmed M, Taylor W, Sm...normal human phosphoribosylpyrophosphate synthetase. J Biol Chem 274:7482-8 (1999) PMID:8702702 Becker MA, Taylor

  10. Data of evolutionary structure change: 1B38A-1WBSA [Confc[Archive

    Lifescience Database Archive (English)


  11. Image files of planarians analyzed by in situ hybridication and immunohistochemical staining - Plabrain DB | LSDB Archive [Life Science Database Archive metadata

    Lifescience Database Archive (English)

    Full Text Available ans or planarian head regions in the regeneration process. Images are displayed in A list of image files of ...file File name: File URL: File size: 2.74MB Simple search URL - Data acquisition method Whole-mou

  12. Draft Genome Sequences of Five Yersinia pseudotuberculosis ST19 Isolates and One Isolate Variant. (United States)

    Platonov, Mikhail E; Blouin, Yann; Evseeva, Vera V; Afanas'ev, Maxim V; Pourcel, Christine; Balakhonov, Sergey V; Vergnaud, Gilles; Anisimov, Andrey P


    We report the first draft genome sequences of five Yersinia pseudotuberculosis isolates of sequence type (ST) 19 and of a variant from one of the five isolates. The total length of assemblies ranged from 4,226,485 bp to 4,274,148 bp, including between 3,808 and 3,843 predicted coding sequences.

  13. Special Operations Forces and Elusive Enemy Ground Targets: Lessons from Vietnam and the Persian Gulf War (United States)


    Enemy Ground Targets team members to fire their weapons as they were lifted from the forest floor . 4 9 Moving through and searching the jungle...MACVSOG headquarters, and as bartenders and waitresses at MACVSOG compounds, where they 61Prados, Blood Road, p. 274. Yearly totals for SHINING BRASS

  14. Curating seeds and other genetic resources for ethnobiology. In: Salick,J.Konchar, K. and Nesbitt, M., editors. Curatring Biocultural Collections: A handbook (United States)

    The National Center for Genetic Resources Preservation (NCGRP) is one of the largest genebanks in the world, currently safeguarding over 875,000 plant collections and 652,295 animal collections, most with agriculture emphasis. This number represents 7,474 different plant species of 1,274 genera. T...


    Institute of Scientific and Technical Information of China (English)


    <正>20042202 Chen Gang (Department of Geology, Northwest University, Xi’an, Shaanxi); Zhao Zhongyuan Natural of Pre-Mesozoic Tectono-Lithostratigraphic Units of North -Huaiyang Belt and Implication for Tectonic Evolution (Journal of Northwest University (Natural Science Edition), ISSN 1000-274X, CN61-1072/N, 33(5), 2003, p. 595 -598, 1 table, 14 refs. )

  16. Development of Biomarkers for Assessing In Situ RDX Biodegradation Potential (United States)


    restriction fragment patterns (TRFPs), a rapid, PCR-based method for the comparison of complex bacterial communities. Journal of Microbiological Methods 31,135...chain reaction method for monitoring RDX-degrading bacteria based on the xplA functional gene. Journal of Microbiological Methods 68,267-274

  17. AcEST: DK959385 [AcEST

    Lifescience Database Archive (English)


  18. 78 FR 4766 - Adoption of Updated EDGAR Filer Manual (United States)


    ... COMMISSION 17 CFR Parts 232, 239, 249, 269, 274 Adoption of Updated EDGAR Filer Manual AGENCY: Securities and...) Filer Manual and related rules to reflect updates to the EDGAR system. The revisions are being made...: Effective Date: January 23, 2013. The incorporation by reference of the EDGAR Filer Manual is approved...

  19. 75 FR 76485 - Certain Electronic Paper Towel Dispensing Devices and Components Thereof; Notice of Commission... (United States)


    ...,182,289; and 7,387,274. 75 FR 28651-2 (May 21, 2010). The complainant named as respondents Kruger Products LP of Mississauga, Canada (``Kruger''); KTG USA LP of Memphis, Tennessee (``KTG USA''); Stefco...: (1) To correct the corporate name of NetPak Chicago; (2) to redefine ``Kruger'' to ``Kruger...

  20. Knowledge workers' creativity and the role of the physical work environment

    NARCIS (Netherlands)

    J. Dul (Jan); C. Ceylan (Canan); F.P.H. Jaspers (Ferdinand)


    textabstractABSTRACT The present study examines the effect of the physical work environment on the creativity of knowledge workers, compared with the effects of creative personality and the social-organizational work environment. Based on data from 274 knowledge workers in 27 SMEs, we conclude that

  1. Domain Modeling: NP_065184.2 [SAHG[Archive

    Lifescience Database Archive (English)

    Full Text Available NP_065184.2 chr1 Solution structure of the tandem four zf-C2H2 domain repeats of mu...rine GLI-Kruppel family member HKR3 c2dlqa_ chr1/NP_065184.2/NP_065184.2_holo_267-376.pdb psi-blast 274A,276

  2. 20 CFR 655.920 - Definitions. (United States)


    ... situated employees in the occupation at the worksite at the time of employment. Administrative Law Judge... students pursuant to Immigration and Naturalization Service regulations at 8 CFR parts 214 and 274a... a course of study at an established institution of learning or other recognized place of study...

  3. Diatoms respire nitrate to survive dark and anoxic conditions

    DEFF Research Database (Denmark)

    Kamp, Anja; de Beer, Dirk; Nitsch, Jana L.


    Diatoms survive in dark, anoxic sediment layers for months to decades. Our investigation reveals a correlation between the dark survival potential of marine diatoms and their ability to accumulate NO3− intracellularly. Axenic strains of benthic and pelagic diatoms that stored 11–274 mM NO3− in th...

  4. Gclust Server: 176060 [Gclust Server

    Lifescience Database Archive (English)

    Full Text Available 176060 DPTM_GSPATP00024285001 Cluster Sequences - 274 no annotation 1 1.00e-99 0.0 ...11.11 0.0 0.0 0.0 0.0 Show 176060 Cluster ID 176060 Sequence ID DPTM_GSPATP00024285001 Link to cluster seque

  5. EST Table: FS936452 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available ivity)|GO:0006508(proteolysis)|GO:0008270(zinc ion binding) 10/09/28 89 %/274 aa ref|NP_001036933.1| molting fluid... carboxypeptidase A [Bombyx mori] dbj|BAD60916.1| molting fluid carboxypeptidase A [Bombyx mori] 10/09

  6. Functional Characterization of Two Novel Human Prostate Cancer Metastasis Related Genes (United States)


    capture microdissection. Science. 274:998- 1001, 1996. 13 31. Listisyn, N, Listisyn, N, and Wigler, M. Cloning the differences between tow ...phytohemaglutinin and phorbol 12-myristate 13- acetate . Anal. Biochem., 240:90-97, 1996. 36. Wang, Z., and Brown, D. D. A gene expression screen. (1991

  7. Resting Metabolic Rate is Not Reduced in Obese Adults With Down Syndrome (United States)

    Fernhall, Bo; Figueroa, Arturo; Collier, Scott; Goulopoulou, Styliani; Giannopoulou, Ifigenia; Baynard, Tracy


    Resting metabolic rate (RMR) of 22 individuals with Down syndrome was compared to that of 20 nondisabled control individuals of similar age (25.7 and 27.4 years, respectively). Using a ventilated hood system, we measured RMR in the early morning after an overnight fast. Peak aerobic capacity Volume of Oxygen (VO2 peak) and body composition were…

  8. In vitro fertilization (IVF) using semi-defined culture conditions from low or high antral follicle count pubertal beef heifers (United States)

    To compare the in vitro fertilization (IVF) and production (IVP) of embryos from low and high antral follicle count (AFC) heifers, AFC were determined on 106 heifers using transrectal ultrasonography. Ten heifers with the lowest AFC (avg. 13.2) and 10 heifers with the highest AFC (avg. 27.4) with ev...

  9. Latino Adolescents' Mental Health: Exploring the Interrelations among Discrimination, Ethnic Identity, Cultural Orientation, Self-Esteem, and Depressive Symptoms (United States)

    Umana-Taylor, Adriana J.; Updegraff, Kimberly A.


    Guided by a risk and resilience framework, the current study used cross-sectional data to examine the degree to which Latino adolescents' (N=274; M age=16.3; 47.1% female) self-esteem, ethnic identity, and cultural orientations mediated or moderated the relation between perceived discrimination and depressive symptoms. Utilizing a multiple group…

  10. Planck intermediate results XXXI. Microwave survey of Galactic supernova remnants

    DEFF Research Database (Denmark)

    Arnaud, M.; Ashdown, M.; Atrio-Barandela, F.;


    The all-sky Planck survey in 9 frequency bands was used to search for emission from all 274 known Galactic supernova remnants. Of these, 16 were detected in at least two Planck frequencies. The radio-through-microwave spectral energy distributions were compiled to determine the mechanism for micr...

  11. 75 FR 64120 - Technical Amendments to Forms N-CSR and N-SAR in Connection With the Comprehensive Iran Sanctions... (United States)


    ... COMMISSION 17 CFR Parts 249 and 274 Technical Amendments to Forms N-CSR and N-SAR in Connection With the... adopting technical amendments to Forms N-CSR and N-SAR under the Securities Exchange Act of 1934 and the... Securities and Exchange Commission (``Commission'') is adopting technical amendments to Form N-CSR \\1\\...

  12. Attacks by “Anonymous” WikiLeaks Proponents not Anonymous

    NARCIS (Netherlands)

    Pras, Aiko; Sperotto, Anna; Moura, Giovane C.M.; Drago, Idilio; Barbosa, Rafael; Sadre, Ramin; Schmidt, Ricardo; Hofstede, Rick


    On November 28, 2010, the world started watching the whistle blower website WikiLeaks to begin publishing part of the 250,000 US Embassy Diplomatic cables. These confidential cables provide an insight on U.S. international affairs from 274 different embassies, covering topics such as analysis of hos

  13. Domain Modeling: NP_059431.1 [SAHG[Archive

    Lifescience Database Archive (English)

    Full Text Available NP_059431.1 chr19 Crystal Structure of Autoinhibited Form of Grp1 Arf GTPase Factor c2r0db_ chr19/NP_059431.1/NP_059431.1_holo_49-390.pdb blast 268K,270G,271G,272G,273R,274V,276T,278

  14. Research funding systems in Australia, New Zealand and the UK

    DEFF Research Database (Denmark)

    Lewis, Jenny; Ross, S


    . This article reports on a study involving interviews with 274 academics at universities in Australia (Melbourne), New Zealand (Auckland) and the UK (Birmingham). Perceptions of the three research funding systems demonstrated significant differences across universities, and some interesting gender and seniority...

  15. Gclust Server: 19387 [Gclust Server

    Lifescience Database Archive (English)

    Full Text Available 19387 Rso_RSc3183 Cluster Sequences Related Sequences(274) 846 PROBABLE HEMAGGLUTIN...IN-RELATED SIGNAL PEPTIDE PROTEIN 5 1.00e-06 14.29 0.0 0.0 6.67 3.23 0.0 Show 19387 Cluster ID 19387 Sequenc

  16. Results of the Cord Blood Transplantation Study (COBLT) : clinical outcomes of unrelated donor umbilical cord blood transplantation in pediatric patients with hematologic malignancies

    NARCIS (Netherlands)

    Kurtzberg, Joanne; Prasad, Vinod K.; Carter, Shelly L.; Wagner, John E.; Baxter-Lowe, Lee Ann; Wall, Donna; Kapoor, Neena; Guinan, Eva C.; Feig, Stephen A.; Wagner, Elizabeth L.; Kernan, Nancy A.


    Outcomes of unrelated donor cord blood transplantation in 191 hematologic malignancy children (median age, 7.7 years; median weight, 25.9 kg) enrolled between 1999 and 2003 were studied (median follow-up, 27.4 months) in a prospective phase 2 multicenter trial. Human leukocyte antigen (HLA) matching

  17. Dragonair- Year-on-Year Rises Continue For Passengers And Cargo

    Institute of Scientific and Technical Information of China (English)


    @@ Passenger numbers at Dragonair rose 13.2% while cargo volumes climbed 23.9%in April compared with the same month in 2004. The airline flew 431,860 passengers last month, 50,274 more than one year ago,and 7.3% up on March.

  18. File list: NoD.Neu.05.AllAg.Brain [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available NoD.Neu.05.AllAg.Brain mm9 No description Neural Brain ERX161927,ERX161926,ERX16192...274,SRX298040,ERX402277,ERX402292,ERX402281 ...

  19. ADA (Trade Name) Adoption Handbook: A Program Manager’s Guide. Version 1.0. (United States)


    Communications Rich Hilliard, MITRE Col. Paul Wickliffe, U.S. Army, Retired 1st Lt. Kurt W. Hoyt, U.S. Air Force William Wilder, U.S. Navy The...Manager AMCDE-SB 5001 Eisenhower Avenue Alexandria, Virginia 22333 (703) 274-9309 U.S. Navy: .Contact: U. Cmdr. Philp Myers, Acting Program Manager ,1

  20. 78 FR 29155 - National Register of Historic Places; Notification of Pending Nominations and Related Actions (United States)


    ... Restricted, Columbus, 13000350 Logan County Booneville Commercial Historic District, E. side of 100 & 200...., Payette, 13000353 NEW JERSEY Essex County Pleasant Days, 274 Old Short Hills Rd., Millburn, 13000354... Spring Rd., Sterling, 13000363 Winchester Independent city Hawthorne and Old Town Spring, 610 &...

  1. 程序性死亡因子-1及其配体在强直性脊柱炎患者外周血的变化

    Institute of Scientific and Technical Information of China (English)

    张华; 骆方军; 周佳斌


    目的 探讨程序性死亡因子-1(PD-1,CD279)及其配体PD-L1(CD274)、PD-L2(CD273)在HLA-B27阳性和阴性强直性脊柱炎(AS)患者外周血的表达及意义.方法 采用流式细胞术检测HLA-B27阳性和阴性AS患者外周血CD8阳性淋巴细胞CD279、CD274和CD273的表达水平.结果 CD279、CD274和CD273在三组中的差异有统计学意义(0.05).结论 HLA-B27阳性AS患者CD279、CD274和CD273的表达水平比HLA-B27阴性AS患者高,可能与疾病的慢性化和迁延不愈有关.

  2. AcEST: BP919007 [AcEST

    Lifescience Database Archive (English)

    Full Text Available =Saccharomyce... 30 7.4 sp|O08999|LTBP2_MOUSE Latent-transforming growth factor b...TVGIVCLSNVEE 274 SS TVG +C + E Sbjct: 276 KNSSGTVGPLCFQELNE 292 >sp|O08999|LTBP2_MOUSE Latent-transforming g

  3. 75 FR 80426 - Defense Federal Acquisition Regulation Supplement; Reporting of Government-Furnished Property (United States)


    ... serially managed, mission essential, sensitive, or controlled inventory. While the proposed rule adds... payments; (4) Intellectual property or software; and (5) Real property. 4. Revise section 211.274-6 to read..., as prescribed in 246.371. (L) Use the provision at 252.247-7026, Evaluation Preference for Use...

  4. 78 FR 51649 - Supplemental Nutrition Assistance Program: Trafficking Controls and Fraud Investigations (United States)


    ... sites and social media. Finally, FNS is issuing an interim final rule provision at 7 CFR 274.6(b)(6... illiterate populations and victims of domestic violence. FNS expects that State agencies will work to ensure... victims of domestic violence, which allows for State agencies to make a determination as they become...

  5. X-ray crystal structure of divalent metal-activated ß-xyloisdase, RS223BX (United States)

    We report the first X-ray structure of a glycoside hydrolase family 43 ß-xylosidase, RS223BX, which is strongly activated by the addition of divalent metal cations. The 2.69 Å structure reveals that the Ca2+ cation is located at the back of the active site pocket. The Ca2+ coordinates to H274 to sta...

  6. Experiment list: SRX573067 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available lonal (Bethyl, A301-274A) || source=IP with Ab anti-INTS11 rabbit polyclonal...=HeLa || cell line=HeLa || treatment=INTS11 occupancy examined cycling non starved wt Hela Cells || antibody=anti-INTS11 rabbit polyc

  7. Experiment list: SRX573068 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available lonal (Bethyl, A301-274A) || source=IP with Ab anti-INTS11 rabbit polyclonal...=HeLa || cell line=HeLa || treatment=INTS11 occupancy examined cycling non starved wt Hela Cells || antibody=anti-INTS11 rabbit polyc

  8. Changes in household composition as determinant of changes in functional ability among old men and women

    DEFF Research Database (Denmark)

    Avlund, Kirsten; Due, Pernille; Holstein, Bjorn E;


    participated in the NORA follow-up study of 75-80 year-old men and women in Jyväskylä, Finland (N=243), Göteborg, Sweden (N=226), and Glostrup, Denmark (N=274). Functional ability was measured by tiredness and need for help in Physical and Instrumental Activities of Daily Living (PADL and IADL). Changes...

  9. 78 FR 31902 - 36(b)(1) Arms Sales Notification (United States)


    ... Government of the Republic of Korea (ROK) has requested a possible sale of F-35 aircraft weapons. These... JUSTIFICATION Republic of Korea--F-35 Aircraft Weapons The Government of the Republic of Korea (ROK) has requested a possible sale of F-35 aircraft weapons. These aircraft weapons include the following: 274...

  10. Alliance for NanoHealth Competitive Research Program (United States)


    439–445 2004. 34. L. C. Junqueira , W. Cossermelli, and R. Brentani, “Differential stain- ing of collagens type I, II and III by Sirius red and...polarization microscopy,” Arch. Histol. Jpn. 413, 267–274 1978. 35. L. C. Junqueira , G. Bignolas, and R. R. Brentani, “Picrosirius stain- ing plus

  11. Letter to the Editor

    Directory of Open Access Journals (Sweden)

    Thomas K. Karikari


    Full Text Available This article is a reaction to a previously published article in the Journal of Microbiology & Biology Education, “Gamification of the Laboratory Experience to Encourage Student Engagement” by Kevin Drace (JMBE 14(2:273–274, 2013.

  12. Experimental/Computational Studies of Combined Cycle Propulsion: Physics and Transient Phenomena in Inlets and Scramjet Combustors (United States)


    Fellow (Stanford University) d) Graduate Students supported all or in part on this grant Justin Wagner - Graduate Student (UT Austin) Agustin Valdivia...Mechanics Meeting, San Diego, CA, February, Paper Number AAS-10-274, 2010. 12. MacMartin, D., "Dynamics and Control of Shock Motion in aNear-Isentropic

  13. Kuidas kirjutatakse ajalugu? / Roger Chartier ; interv. Marek Tamm

    Index Scriptorium Estoniae

    Chartier, Roger


    Kirjanduslikest tekstidest sotsiaalajaloo uurimisallikana, juhuse ja paratamatuse vahekorrast ajaloos ja Prantsuse revolutsiooni käsitlusest Pariisi õppe- ja teaduskeskuse Ecole des Hautes Etudes en Sciences Sociales professori R. Chartier'i teostes. Varem ilm.: Tekstid, praktikad ja lugejad : intervjuu Roger Chartier'ga // Chartier, Roger. Prantsuse revolutsiooni kultuurilised lätted. - Tallinn, 2002. - Lk. 274-290

  14. The Utilisation of the Internet by Palestinian English Language Teachers Focusing on Uses, Practices and Barriers and Overall Contribution to Professional Development (United States)

    Kabilan, Muhammad Kamarul; Rajab, Belal Mousa


    The paper describes a study designed to investigate the utilisation of the Internet by English Language teachers in Gaza focusing on uses, practices and barriers. A questionnaire was developed based on literature (Kabilan 2003; Kabilan & Mohamed Amin 2002) and was administered to 274 English language teachers in Gaza schools. Data reveal that…

  15. Decomposition of Repetition Priming Processes in Word Translation (United States)

    Francis, Wendy S.; Duran, Gabriela; Augustini, Beatriz K.; Luevano, Genoveva; Arzate, Jose C.; Saenz, Silvia P.


    Translation in fluent bilinguals requires comprehension of a stimulus word and subsequent production, or retrieval and articulation, of the response word. Four repetition-priming experiments with Spanish-English bilinguals (N = 274) decomposed these processes using selective facilitation to evaluate their unique priming contributions and factorial…

  16. Mechanism of Ras Activation by TGFBeta (United States)


    transcriptional activity of the vitamin D receptor (Yanagi- sawa et al, 1999). Smad3 and Smad4 can also associate with the acute myeloid leukemia family of... Ishii , S. (1999). ATF-2 is a common nuclear target of Smad and TAK1 pathways in transforming growth factor-ß signaling. J Biol Chem 274, 8949

  17. Variation in working effort in Danish Little Owls Athene noctua

    DEFF Research Database (Denmark)

    Holsegård-Rasmussen, Miriam H.; Sunde, Peter; Thorup, K.


    with extinction. The study is based on 143 one-hour surveys of breeding and 274 surveys of non-breeding Little Owls (27 territorial individuals on 14 territories). Working effort is calculated as the total linear distance between all observed consecutive telemetry fixes during one-hour surveys (Minimum Flight...

  18. EST Table: FS830202 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available FS830202 E_FL_fmgV_34C08_R_0 10/09/28 94 %/274 aa ref|NP_001040163.1| ischemia/repe...rfusion inducible protein [Bombyx mori] gb|ABD36179.1| ischemia/reperfusion inducible protein [Bombyx mori

  19. 17 CFR 240.10b-18 - Purchases of certain equity securities by the issuer and others. (United States)


    ... report their repurchasing activity as required by Item 8 of Form N-CSR (17 CFR 249.331; 17 CFR 274.128). (a) Definitions. Unless otherwise provided, all terms used in this section shall have the same meaning as in the Act. In addition, the following definitions shall apply: (1) ADTV means the...

  20. 10 CFR 150.4 - Communications. (United States)


    ... 10 Energy 2 2010-01-01 2010-01-01 false Communications. 150.4 Section 150.4 Energy NUCLEAR... OFFSHORE WATERS UNDER SECTION 274 General Provisions § 150.4 Communications. Except where otherwise specified in this part, all communications and reports concerning the regulations in this part should...

  1. EST Table: FS917567 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available catabolic process) 10/09/28 71 %/272 aa ref|XP_001653664.1| ubiquitin fusion degradaton protein [Aedes aegy...pti] gb|EAT39129.1| ubiquitin fusion degradaton protein [Aedes aegypti] 10/09/12 65 %/274 aa FBpp0225719|Dvi

  2. 75 FR 42575 - Electronic Signature and Storage of Form I-9, Employment Eligibility Verification (United States)


    ... SECURITY 8 CFR Part 274a RIN 1653-AA47 Electronic Signature and Storage of Form I-9, Employment Eligibility.... Regulatory History In June 2006, DHS published an interim final rule to permit electronic signature and... because electronic signature and storage technologies are optional, DHS expects that small entities...

  3. Quantitative analysis of HGF and EGF-dependent phosphotyrosine signaling networks

    DEFF Research Database (Denmark)

    Hammond, Dean E; Hyde, Russell; Kratchmarova, Irina;


    549 lung adenocarcinoma cells with EGF or HGF. In total, we obtained quantitative information for 274 proteins, which respond to either or both stimuli by >1.5 fold changes in enrichment, following immuno-precipitation with antiphosphotyrosine antibodies. The data reveal a high degree of overlap...

  4. College Students' Social Justice Interest and Commitment: A Social-Cognitive Perspective (United States)

    Miller, Matthew J.; Sendrowitz, Kerrin; Connacher, Christopher; Blanco, Susana; de La Pena, Cristina Muniz; Bernardi, Shaina; Morere, Lauren


    In this study, the authors examined the degree to which social-cognitive career theory (SCCT; R. W. Lent, S. D. Brown, & G. Hackett, 1994) explained the development of social justice interest and commitment. Data from 274 college students and latent variable path modeling were used to test theoretically and empirically derived SCCT direct and…

  5. Similarity in General Mental Ability in Bedouin Full and Half Siblings. (United States)

    Elbedour, Salman; Hur, Yoon-Mi; Bouchard, Thomas J., Jr.


    A battery of "g" loaded mental ability tests was administered to 274 Bedouin children and adolescents, full and half siblings from 106 families. Results demonstrate internal validity for the tests in this cultural context and support the idea that shared family environment is a strong determinant of sibling similarity for children in the given age…

  6. Data of evolutionary structure change: 1DFIA-3FNFD [Confc[Archive

    Lifescience Database Archive (English)


  7. Gclust Server: 17217 [Gclust Server

    Lifescience Database Archive (English)

    Full Text Available 17217 Bja_bll4927 Cluster Sequences Related Sequences(26) 274 hypothetical protein ...6 1.00e-19 0.0 0.0 4.0 0.0 9.68 0.0 Show 17217 Cluster ID 17217 Sequence ID Bja_bll4927 Link to cluster sequ

  8. Dicty_cDB: Contig-U14809-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available ) Plasmodium falciparum adhesive-like protein pseud... 40 0.10 2 ( CU302368 ) Pig...4B16 in... 36 0.10 4 ( AC079638 ) Genomic sequence for Mus musculus, clone RP23-274... 40 0.10 2 ( AF324831

  9. Data of evolutionary structure change: 1B1ZA-2NTSA [Confc[Archive

    Lifescience Database Archive (English)


  10. 40 CFR Appendix A to Part 97 - Final Section 126 Rule: EGU Allocations, 2004-2007 (United States)


    ... 7 337 OH R E BURGER 2864 8 274 OH RICHARD GORSUCH 7286 1 146 OH RICHARD GORSUCH 7286 2 138 OH RICHARD GORSUCH 7286 3 144 OH RICHARD GORSUCH 7286 4 146 OH W H SAMMIS 2866 1 402 OH W H SAMMIS 2866 2...

  11. DMPD: The oxidation of lipoproteins by monocytes-macrophages. Biochemical andbiological mechanisms. [Dynamic Macrophage Pathway CSML Database

    Lifescience Database Archive (English)

    Full Text Available logical mechanisms. Chisolm GM 3rd, Hazen SL, Fox PL, Cathcart MK. J Biol Chem. 1999 Sep 10;274(37):25959-62...onocytes-macrophages. Biochemical andbiological mechanisms. Authors Chisolm GM 3rd, Hazen SL, Fox PL, Cathcart

  12. 40 CFR 266.210 - What definitions apply to this subpart? (United States)


    ... under subsection 274b of the Atomic Energy Act of 1954, as amended (68 Stat. 919), to assume... sufficient to form a critical mass. Certified delivery means certified mail with return receipt requested, or... regulated by NRC, or NRC Agreement States, under authority of the Atomic Energy Act of 1954, as amended....

  13. Associations between somatic cell count patterns and the incidence of clinical mastitis

    NARCIS (Netherlands)

    Haas, de Y.; Barkema, H.W.; Schukken, Y.H.; Veerkamp, R.F.


    Associations between clinical mastitis (CM) and the proportional distribution of patterns in somatic cell count (SCC) on a herd level were determined in this study. Data on CM and SCC over a 12-month period from 274 Dutch herds were used. The dataset contained parts of 29,719 lactations from 22,955

  14. CpG-ODN attenuates pathological cardiac hypertrophy and heart failure by activation of PI3Kα-Akt signaling.

    Directory of Open Access Journals (Sweden)

    Liang Yang

    Full Text Available Phosphoinositide-3-kinase α (PI3Kα represents a potential novel drug target for pathological cardiac hypertrophy (PCH and heart failure. Oligodeoxynucleotides containing CpG motifs (CpG-ODN are classic agonists of Toll-like receptor 9 (TLR9, which typically activates PI3K-Akt signaling in immune cells; however, the role of the nucleotide TLR9 agonists in cardiac myocytes is largely unknown. Here we report that CpG-ODN C274 could both attenuate PCH and improve cardiac dysfunction by activating PI3Kα-Akt signaling cascade. In vitro studies indicated that C274 could blunt reactivation of fetal cardiac genes and cell enlargement induced by a hypertrophic agent, isoproterenol. The anti-hypertrophic effect of C274 was suppressed by a pan-PI3K inhibitor, LY294002, or a small interfering RNA targeting PI3Kα. In vivo studies demonstrated that PCH, as marked by increased heart weight (HW and cardiac ANF mRNA, was normalized by pre-administration with C274. In addition, Doppler echocardiography detected cardiac ventricular dilation, and contractile dysfunction in isoproterenol-treated animals, consistent with massive replacement fibrosis, reflecting cardiac cell death. As expected, pre-treatment of mice with C274 could prevent cardiac dysfunction associated with diminished cardiac cell death and fibrosis. In conclusion, CpG-ODNs are novel cardioprotective agents possessing antihypertrophic and anti-cell death activity afforded by engagement of the PI3Kα-Akt signaling. CpG-ODNs may have clinical use curbing the progression of PCH and preventing heart failure.

  15. Suppression of Instability in Rotatory Hydromagnetic Convection

    Indian Academy of Sciences (India)

    Joginder S Dhiman


    Recently discovered hydrodynamic instability [1], in a simple Bénard configuration in the parameter regime 02 > 1 under the action of a nonadverse temperature gradient, is shown to be suppressed by the simultaneous action of a uniform rotation and a uniform magnetic field both acting parallel to gravity for oscillatory perturbations whenever $(\\mathscr{Q}_1/^2+\\mathscr{J}/^4) > 1$ and the effective Rayleigh number $\\mathcal{R}$(1-02) is dominated by either 274(1 + 1/1)/4 or 274/2 according as 1 ≥ 1 or 1 ≤ 1 respectively. Here 0 is the temperature of the lower boundary while 2 is the coefficient of specific heat at constant volume due to temperature variation and 1, $\\mathcal{R}, \\mathscr{Q}$ and $\\mathscr{T}$ respectively denote the magnetic Prandtl number, the Rayleigh number, the Chandrasekhar number and the Taylor number.

  16. A method to measure the effect of food appearance factors on children´s visual preferences

    DEFF Research Database (Denmark)

    Kildegaard, Heidi; Olsen, A.; Gabrielsen, G.


    The aim of the study was to examine children’s visual preferences for two food products; yoghurts and smoothies, by using a conjoint layout. In total, 274 children performed an incomplete ranking of 8 pictures formed by three factors each with two levels (23 design). The three food appearance fac...... between food appearance factors and segmentation factors were found. Additionally gender and ethnicity were found to be influential drivers for food choice.......The aim of the study was to examine children’s visual preferences for two food products; yoghurts and smoothies, by using a conjoint layout. In total, 274 children performed an incomplete ranking of 8 pictures formed by three factors each with two levels (23 design). The three food appearance...

  17. Development of renewable energy 2014/15. Wind power keeps the energy turnaround on course; Entwicklung der erneuerbaren Energien 2014/15. Windkraft haelt die Energiewende auf Kurs

    Energy Technology Data Exchange (ETDEWEB)

    Musiol, Frank; Bickel, Peter; Nieder, Thomas [Zentrum fuer Sonnenenergie- und Wasserstoff-Forschung Baden-Wuerttemberg (ZSW), Stuttgart (Germany)


    An expansion of wind energy use in barely thought possible extent has contributed significantly to the fact that electricity production achieving a significant increase of renewable energy in 2014 and their share in gross electricity consumption could rise to 27.4% in Germany. So the wind ensured that the energy transition could be kept on course, as in the renewable energy in the heating and transport sectors did like in previous years, little. [German] Ein Ausbau der Windenergienutzung in kaum fuer moeglich gehaltenem Ausmass hat wesentlich dazu beigetragen, dass die Stromerzeugung aus erneuerbaren Energien auch im Jahr 2014 ein deutliches Plus erzielen und ihr Anteil am Bruttostromverbrauch in Deutschland auf 27.4 % steigen konnte. So sorgte die Windkraft dafuer, dass die Energiewende weiter auf Kurs gehalten werden konnte, denn bei den Erneuerbaren im Waerme- und Verkehrssektor tat sich wie schon in den Vorjahren wenig.

  18. Planck intermediate results XXXI. Microwave survey of Galactic supernova remnants

    DEFF Research Database (Denmark)

    Arnaud, M.; Ashdown, M.; Atrio-Barandela, F.


    The all-sky Planck survey in 9 frequency bands was used to search for emission from all 274 known Galactic supernova remnants. Of these, 16 were detected in at least two Planck frequencies. The radio-through-microwave spectral energy distributions were compiled to determine the mechanism for micr......The all-sky Planck survey in 9 frequency bands was used to search for emission from all 274 known Galactic supernova remnants. Of these, 16 were detected in at least two Planck frequencies. The radio-through-microwave spectral energy distributions were compiled to determine the mechanism...... for microwave emission. In only one case, IC 443, is there high-frequency emission clearly from dust associated with the supernova remnant. In all cases, the low-frequency emission is from synchrotron radiation. As predicted for a population of relativistic particles with energy distribution that extends...

  19. Ecology, Inhibitory Activity, and Morphogenesis of a Marine Antagonistic Bacterium Belonging to the Roseobacter Clade

    DEFF Research Database (Denmark)

    Bruhn, Jesper Bartholin; Nielsen, Kristian Fog; Hjelm, Mette


    correlated with the appearance of a brownish pigment and was only formed in marine broth under static growth conditions. A thick biofilm of multicellular star-shaped aggregated cells formed at the air-liquid interface under static growth conditions. Here, the bioactive compound was the base peak in the LC...... and inhibited their growth in marine broth. Liquid chromatography (LC) with both UV spectral detection and high-resolution mass spectrometry (HR-MS) identified the known antibacterial compound thiotropocin or its closely related precursor tropodithietic acid in the bioactive fractions. Antibacterial activity...... identified the acylated homoserine lactone (3-hydroxy-decanoyl homoserine lactone) from cultures of Roseobacter 27-4 using LC-HR-MS. The signal molecule was primarily detected in stagnant cultures. Roseobacter 27-4 grew between 10 and 30{degrees}C but died rapidly at 37{degrees}C. Also, the antibacterial...

  20. FAST TRACK COMMUNICATION: Quantum chaos on discrete graphs (United States)

    Smilansky, Uzy


    Adapting a method developed for the study of quantum chaos on quantum (metric) graphs (Kottos and Smilansky 1997 Phys. Rev. Lett. 79 4794, Kottos and Smilansky 1999 Ann. Phys., NY 274 76), spectral ζ functions and trace formulae for discrete Laplacians on graphs are derived. This is achieved by expressing the spectral secular equation in terms of the periodic orbits of the graph and obtaining functions which belong to the class of ζ functions proposed originally by Ihara (1966 J. Mat. Soc. Japan 18 219) and expanded by subsequent authors (Stark and Terras 1996 Adv. Math. 121 124, Kotani and Sunada 2000 J. Math. Sci. Univ. Tokyo 7 7). Finally, a model of 'classical dynamics' on the discrete graph is proposed. It is analogous to the corresponding classical dynamics derived for quantum graphs (Kottos and Smilansky 1997 Phys. Rev. Lett. 79 4794, Kottos and Smilansky 1999 Ann. Phys., NY 274 76).

  1. Dynamics and Mechanism of Efficient DNA Repair Reviewed by Active-Site Mutants (United States)

    Tan, Chuang; Liu, Zheyun; Li, Jiang; Guo, Xunmin; Wang, Lijuan; Zhong, Dongping


    Photolyases repair the UV-induced pyrimidine dimers in damage DNA via a photoreaction which includes a series of light-driven electron transfers between the two-electron-reduced flavin cofactor FADH^- and the dimer. We report here our systematic studies of the repair dynamics in E. coli photolyase with mutation of several active-site residues. With femtosecond resolution, we observed the significant change in the forward electron transfer from the excited FADH^- to the dimer and the back electron transfer from the repaired thymines by mutation of E274A, R226A, R342A, N378S and N378C. We also found that the mutation of E274A accelerates the bond-breaking of the thymine dimer. The dynamics changes are consistent with the quantum yield study of these mutants. These results suggest that the active-site residues play a significant role, structurally and chemically, in the DNA repair photocycle.


    Institute of Scientific and Technical Information of China (English)


    <正>20082513 Chen Guocheng(State Key Labo- ratory of Marine Geology,Tongji University, Shanghai 200092,China);Zheng Hongbo Sedimentary Records of Volcanic Activities in the South China Sea over the Past 480 ka (Marine Geology & Quaternary Geology, ISSN0256—1492,CN37—1117/P,27(4), 2007,p.69—76,4 illus.,1 table,25 refs., with English abstract) Key words:sedimentary sequence,South China Sea

  3. Identification of Candidate Zero Maintenance Paving Materials. Volume 1 (United States)


    asphalts could not be located, it is generally believed that the material is relatively stable at normal ambient temperatures. 4.8 DURABILITY 4.8.1 Freeze...Con Azufre," Proceedings, Second Interna- tional Seminar on Concrete Technology, Inscituto de Ingenieria Civil de la Universidad Autonoma de Nuevo Leon...Seminar on Concrete Technology, ]nstituto de Ingenieria Civil de la Univarsidad Autonoma de Nuevo Leon, Monterrey, Mexico, Mcr 1975, pp 261-274. 49

  4. Difference and ratio plots

    DEFF Research Database (Denmark)

    Svendsen, Anders Jørgen; Holmskov, U; Bro, Peter


    hitherto unnoted differences between controls and patients with either rheumatoid arthritis or systemic lupus erythematosus. For this we use simple, but unconventional, graphic representations of the data, based on difference plots and ratio plots. Differences between patients with Burkitt's lymphoma...... and systemic lupus erythematosus from another previously published study (Macanovic, M. and Lachmann, P.J. (1979) Clin. Exp. Immunol. 38, 274) are also represented using ratio plots. Our observations indicate that analysis by regression analysis may often be misleading....

  5. Whole genome shotgun sequencing of Brassica oleracea and its application to gene discovery and annotation in Arabidopsis


    Ayele, Mulu; Haas, Brian J.; Kumar, Nikhil; Wu, Hank; Xiao, Yongli; Van Aken, Susan; Utterback, Teresa R.; WORTMAN, Jennifer R.; White, Owen R.; Town, Christopher D


    Through comparative studies of the model organism Arabidopsis thaliana and its close relative Brassica oleracea, we have identified conserved regions that represent potentially functional sequences overlooked by previous Arabidopsis genome annotation methods. A total of 454,274 whole genome shotgun sequences covering 283 Mb (0.44×) of the estimated 650 Mb Brassica genome were searched against the Arabidopsis genome, and conserved Arabidopsis genome sequences (CAGSs) were identified. Of these ...

  6. Aquatic Toxicity Screening of an ACWA Secondary Waste, GB-Hydrolysate (United States)


    toxicity the bioassay must include a minimum of four dilutions exhibiting a dose response, plus a control consisting of V.fischeri bioluminescent...typically used in the preliminary screening process and is not intended to be a substitute for risk assessment. This system assigns a score (0-9; 9 being...Aquatic Toxicological Research with Organophosphate Insecticides. Ecotoxicology Environmental Saf 1991, 21 (3), pp 266-274. 10. Maas, J.L. Toxicity of

  7. Strategic Plan for Electronic Commerce, Defense Personnel Support Center (United States)


    AD-A274 243 Strategic Plan for Electronic Commerce Defense Personnel Support Center DTIC %!" . FLECTE .: UEC3 0 199 3 -I CUSTOMER SATISFACTION 93 12...220 3 &tiuini nm Best Available Copy Strategic Plan for Electronic Commerce Defense Personnel Support Center NTIS C? ~- j CUSTOMER Avao OrK...Concept of Operations and Projects ........... 6-4 Benefits and Costs of Electronic Commerce in the Medical Directorate

  8. Antiviral phenolics from the leaves of Cleistocalyx operculatus

    DEFF Research Database (Denmark)

    Ha, Thi Kim Quy; Dao, Trong Tuan; Nguyen, Ngoc Hieu


    different influenza viruses, including H1N1, H9N2, novel H1N1, and oseltamivir-resistant novel H1N1 (H274Y mutation) expressed in HEK293 cells (IC50 values ranging from 5.07 ± 0.94 μM to 9.34 ± 2.52 μM, respectively). Kinetic experiments revealed the non-competitive inhibitory mode of both compounds 6 and 8...

  9. Effect of UV-B radiation on the fatty acid composition of the marine phytoplankter Tetraselmis sp.: Relationahip to cellular pigments

    Digital Repository Service at National Institute of Oceanography (India)

    Goes, J.I.; Handa, N.; Taguchi, S.; Hama, T.

    : 259-274,1994 MARINE ECOLOGY PROGRESS SERIES Mar. Ecol. Prog. Ser. I Published November 17 l Effect of UV-B radiation on the fatty acid composition of the marine phytoplankter Tetraselmis sp.: relationship to cellular pigments Joaquim I. ~oesl... and pig- ment composition of Tetraselmis sp. resulting from exposure to UV-B radiation. Although fatty acids con- stitute a small proportion of the total organic matter synthesized by marine phytoplankton (Hama & Handa 1987, Hama 1991...

  10. 服务器市场风云

    Institute of Scientific and Technical Information of China (English)


    戴尔推出三款新型服务器;捷洲推双校服务器新品I1-274TH;方正推出圆明MT100 1400四校服务器;联想发布最新四核服务器 性能提升近五成;IBM推出全新BladeCenter HT系统……

  11. Intimate Partner Violence: What Health Care Providers Need to Know (United States)


    and mental health diagnoses in perinatal women. J Womens Health (Larchmt). 2011 Dec;20(12):1797-803.  Moore AM, Frohwirth L, Miller E. Male ...reduce risk associated with reproductive coercion. Contraception . 2011 Mar;83(3):274-80.  O’Campo P, Kirst M, Tsamis C, Chambers C, Ahmad F...Gerlock, et al. Documentation of screening for perpetration of intimate partner violence in male veterans with PTSD. Amer J Nurs 2011;111(11):26-32

  12. Understanding obsessive-compulsive personality disorder in adolescence: a dimensional personality perspective


    Aelterman, Nathalie; Decuyper, Mieke; Fruyt, Filip De


    The validity of the Axis II Obsessive-Compulsive Personality Disorder (OCPD) category and its position within the Cluster C personality disorder (PDs) section of the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV, APA, 2000) continues to be a source of much debate. The present study examines the associations between general and maladaptive personality traits and OCPD symptoms, prior to and after controlling for co-occurring PD variance, in a general population sample of 274 Fle...

  13. Mental Health of Students in Sports School%体校学生心理健康状况调查

    Institute of Scientific and Technical Information of China (English)




  14. Clinical Investigation Program: Annual Progress Report (United States)


    Failure ....... 82 90/124 C The Effectiveness of Octreotide (Sandostatin*) to Prevent Pancreatitis Caused by Endoscopic Pancreacto- Biliary Procedures: A...203 T Cryoprecipitate in the Treatment of Seroma . 275 92/204 0 Effect of Intravenous Erythromycin on Post- Operative Ileus ...JE: Cutaneous sarcoidal granulo- mas in a patient with primary biliary cirrhosis. Cutis 49:271- 274, 1992. Homas PB, David-Bajar KM, Fitzpatrick JE

  15. Relict faunal testimony for sea-level fluctuations off Myanmar (Burma)

    Digital Repository Service at National Institute of Oceanography (India)

    Panchang, R.; Nigam, R.; Raviprasad, G.V.; Rajagopalan, G.; Ray, D.K.; Hla, U Ko Yi

    of External Affairs with the support of the Council of Scientific and Industrial Research and Department of Ocean Development, New Delhi) and Government of Myanmar (Min- istry of Education). The authors thank Director, National In- stitute of Oceanography (NIO... changes along Indian Coasts. Proceedings of the Indian National Science Academy, 58 : 461-472. Murray, J. W. 1973, Distribution and Ecology of Living Benthic Foraminiferids: Heinemann Educational Books, London, 274 p. Pirazzoli, P.A. 1991. World Atlas...

  16. Inhibition of Breast Cancer-Induced Angiogenesis by a Diverged Homeobox Gene (United States)


    Lett 499:274–278. ten Berge D, Brouwer A, Korving J, et al.: 1998. Prx1 and Prx2 in skeletogenesis: roles in the craniofacial region, inner ear and...endothelial cells in an invasive state and prevents vessel maturation, leading to vascular malformations and endotheliomas. In diabetic mice, HOXD3...chorioallantoic membrane retains endothelial cells in an invasive state and prevents vessel maturation, leading to vas- cular malformations and

  17. Significant association between ABO blood group and pancreatic cancer

    Institute of Scientific and Technical Information of China (English)

    Julia; B; Greer; Mark; H; Yazer; Jay; S; Raval; M; Michael; Barmada; Randall; E; Brand; David; C; Whitcomb


    AIM:To evaluate whether the ABO blood group is related to pancreatic cancer risk in the general population of the United States.METHODS:Using the University of Pittsburgh's clinicalpancreatic cancer registry,the blood donor database from our local blood bank (Central Blood Bank),and the blood product recipient database from the regional transfusion service (Centralized Transfusion Service) in Pittsburgh,Pennsylvania,we identified 274 pancreatic cancer patients with previously determined serological ABO bloo...

  18. Computer-Aided Process and Tools for Mobile Software Acquisition (United States)


    deploy mobile devices” ( Kenyon , 2012a). The Defense Information Systems Agency (DISA) has opened a program office and issued a request for information to...solicit ideas from industry for ways to provide the mobile device management (MDM) services and to run an applications store ( Kenyon 2012b), and...8(3), 231–274. Kenyon , H. (2012a, January 11). Army sets tone for government’s mobile enterprise with Android. Retrieved from http

  19. Blind One-Bit Compressive Sampling (United States)


    notation and recalling some background from convex analysis . For the d-dimensional Euclidean space Rd, the class of all lower semicontinuous convex...compressed sensing, Applied and Computational Harmonic Analysis , 27 (2009), pp. 265 – 274. [3] P. T. Boufounos and R. G. Baraniuk, 1-bit compressive sensing...Convergence analysis of the algorithm is presented. Our approach is to obtain a sequence of optimization problems by successively approximating the ℓ0

  20. Anesthesia in a Combat Environment (United States)


    1969 19. Stoelting RK, Reis RR, Longnecker DE: Hemodynamic responses to nitrous oxide-halothane and halothane in patients with valvular heart disease . Anesthesiology...274- 285, 1971 28. Stoelting RK, Gibbs PS: Hemodynamic effects of morphine and morphine- nitrous oxide in valvular heart disease and coronary artery...responses to nitrous oxide-halothane and halothane in patients with valvular heart disease , Anesthesiology 37:430-435, 1975 34. Price HL: Myocardial

  1. Muscle Sympathetic Nerve Activity During Intense Lower Body Negative Pressure to Presyncope in Humans (United States)


    Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology, 1996). As diastolic arterial pressure... dogs . Am J Physiol Heart Circ Physiol 274, H1099–H1105. Preiss G & Polosa C (1974). Patterns of sympathetic neuron activity associated with Mayer waves...Society of Cardiology and the North American Society of Pacing and Electrophysiology (1996). Heart rate variability: standards of measurement

  2. The influence of distance and quality of care on place of delivery in rural Ghana



    Facility delivery is an important aspect of the strategy to reduce maternal and newborn mortality. Geographic access to care is a strong determinant of facility delivery, but few studies have simultaneously considered the influence of facility quality, with inconsistent findings. In rural Brong Ahafo region in Ghana, we combined surveillance data on 11,274 deliveries with quality of care data from all 64 delivery facilities in the study area. We used multivariable multilevel logistic regressi...

  3. Ultraviolet light emitting diodes by ammonia molecular beam epitaxy on metamorphic (KAUST Repository

    Young, Erin C.


    © 2015. In this paper we demonstrate ultraviolet (UV) light emitting diodes (LEDs) grown on metamorphic AlGaN buffers on freestanding GaN (202-1) substrates by ammonia assisted molecular beam epitaxy (MBE). Misfit and related threading dislocations were confined to the stress relaxed, compositionally graded buffer layers, and single quantum well devices emitting at 355, 310 and 274. nm were grown on top of the graded buffers. The devices showed excellent structural and electrical (I-. V) characteristics.

  4. On the Effectiveness of Military Institutions: Historical Case Studies from World War I, The Interwar Period, and World War II. Volume 3. World War II (United States)


    as possible) and bluster: ’education fla cultural counts for nothing’. "L4 cultura might indeed count for nothing until It came time to navigate 3 in...1007, Cant. Z 506) (Fortunato Minniti, ’La politica Industziale 3 del Ministero dell*Aeronautica. Mercato, Planificazione, Sviluppo (1935-1943),’ Storia...remark: Minnici, ’La politica Industriale," p. 274. 12. See D’Avanzo, Ali e voltrone, pp. 334-35, tot an energetic but undocumented statement of the

  5. Biodegradation and Transformation of Nitroaromatic Compounds (POSTPRINT) (United States)


    hlorophenoxyaaoc acid in the soil.]. Sci. Food Agric. 3:2 68-274. 5. Barr, D.P., and S.D. Aust. 1994. Mec hanisms white rot fungi use to degrade pollutants...79. Venkatadri, R., and R. L. Irvine. 1993. Cultivation of Phanerochaece chrysosporium and production of lignin per· oxidase in novel biofilm ...nirrophenol and m-nitroph enol by a Pseudomonas pmul.a. ]. Agric. Food Chern . 3Z:238- 24Z..

  6. Manpower Management (Officer and Enlisted) AFSC 74XX/733XX (United States)



  7. Contributions to the Oceanography of the Western Alboran Sea. (United States)


    Aerospaclal, Madrid, Spain . .. (4) Instituto Espanol de Oceanografia , Madrid, Spain (5) Members of the Donde Va Group are listed on page 22 L A..- 1PREFACE...October 1983. Instituto Espanol de Oceanografia (extended abstracts in English, short abstracts in Spanish and English), 1984. Parrilla, G. and T.H...MA 02543 Gregorio Parrilla Instituto Espanol de Oceanografia , Alcala 27-4*, 28014, Madrid, Spain In 1982 we did two CTD surveys of the western Alboran

  8. United States National Security Interests and the Republic of Mexico. (United States)


    The perceptions that have been colored by history are sharpened by differences and dispari- ties separating the two nations. Octavio Paz , a...Stoessel, Jr., "Foreign Policy Priorities in Asia," Current Policy, No. 274, (April 24, 1981), p. 1. 14 Octavio Paz , Mexico and the U.S.: Positions and... Paz expressed it, "our countries are neighbors condemned to live alongside each other." The relationship began even before the two nations existed

  9. Expanding the Boundaries of Behavioral Integrity in Organizations (United States)


    feedback, and acceptance of decisions. Positive trust outcomes even have been demonstrated in a more intimate relationship – between an online ... shopper and the e-retailer (Chen & Dibb, 2010). Even here, trust in the website predicted positive attitudes and intentions toward the company... online retail context: Exploring the antecedents and consequences. Psychology & Marketing, 27(4): 323-346. Chung-Herrera, B. G., & Lankau, M. J. 2005

  10. Fat content of expressed breast milk: a case for quality control.


    Spencer, S A; Hull, D


    Expressed breast milk used to feed preterm infants is precious and so, despite heterogeneity of composition, all available milk is used. A study of 274 samples of expressed breast milk supplied by preterm mothers and National Childbirth Trust donors showed pronounced variation in fat content as measured by the "creamatocrit" method. This was not due to differences between term and preterm mothers or between transitional and mature milk. The composition was affected by diurnal variation and me...

  11. A study on sexual health knowledge, sexual attitudes and sex-related behaviors of university students in Hefei, China


    Chi, Xinli; 遲新麗


    This present research aimed (1) to examine the level of sexual health knowledge, patterns of sexual attitudes and prevalence of sex-related behaviours among college students in contemporary China; (2) to explore factors predicting knowledge, attitude and behavior regarding sexuality; and (3) to assess gender differences in both characteristics and correlates. Based on data collected from 274 college students (167 male and 107 female) by the way of convenience sampling, in Hefei, China, Ph...

  12. Other endocrinologic disorders

    Institute of Scientific and Technical Information of China (English)


    2008405 Male pseudohermaphroditism due to 17β-hydroxysteroid dehydrogenase 3 deficiency. YANG Jun(杨军), et al. Shanghai Clin Endocrin & Metab Dis Center, Ruijin Hosp, Shanghai Jiaotong Univ, Shanghai 200025. Chin J Endocrinol Metab 2008;24(3):272-274. Objective To investigate the clinical and genetic characteristics in a patient with 17β-hydroxy-steroid dehydrogenase (17β-HSD) 3 deficiency

  13. The Evolution of the Mexican Military: From the Mexican Revolution In 1910 to 2014 (United States)


    Alicia Hernández Chávez, “Origen y ocaso del ejército porfiriano,” Historia Mexicana 39 (1989), 285. 72 Camp, “Mexico,” 274–275. 25...1. Chávez, Alicia Hernández. “Origen y ocaso del ejercito porfiriano.” Historia Mexicana 39 (1989): 257-296. Corcoran, Katherine. “Analysis: Mexico

  14. A Comparative Study of Linkage Indexes: Co-assignee, Reciprocal Citation, Patent Coupling and Co-patent

    Directory of Open Access Journals (Sweden)

    Szu-chia Scarlett Lo


    Full Text Available Four indexes including co-assignees, reciprocal citation, patent coupling and co-patent were examined in this study to reveal the meanings of the correlations generated via different citation linkages. This study includes 6,274 genetic engineering patents, and 16 primary assignees identified by Bradford model analysis as the base for correlation analysis. The results show that there are four cluster types, including technological affiliated, technological competitor correlated, commercial collaborated and technological isolated.

  15. Órfãos de terapia medicamentosa: a administração de medicamentos por via intravenosa em crianças hospitalizadas


    Peterlini, Maria Angélica Sorgini [UNIFESP; Chaud, Massae Noda [UNIFESP; Pedreira,Mavilde da Luz Gonçalves


    Descriptive study, developed at a general university hospital that aimed at verifying the number and types of IV drugs administered to children, the adequacy of their pharmacological presentation for pediatric use and the estimated costs of some drugs administration. In a period of 30 days, 8,245 drug doses were administered, with an average of 274.83 doses a day, and a yearly estimation of 98.940. The most used drugs were methylprednisolone, vancomycin, furosemide, ranitidine, penicillin, am...

  16. Dicty_cDB: Contig-U13122-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available : 95,242,211,685 Length adjustment: 22 Effective length of query: 88 Effective le...ngth of database: 93,199,600,587 Effective search space: 8201564851656 Effective search space used: 82015648...051,180,864 Length adjustment: 10 Effective length of query: 26 Effective length of database: 1,018,815,274 Effective... search space: 26489197124 Effective search space used: 26489197124 Neig

  17. Dicty_cDB: Contig-U14008-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available 95,242,211,685 Length adjustment: 22 Effective length of query: 88 Effective length of database: 93,199,600,587 Effective... search space: 8201564851656 Effective search space used: 8201564851656 X1: 11 (21.8 bits) S2:...ase: 1,051,180,864 Length adjustment: 10 Effective length of query: 26 Effective ...length of database: 1,018,815,274 Effective search space: 26489197124 Effective search space used: 264891971

  18. Determing the Time Dependence of Electrical Gradients in Railguns using the Transmission Line (United States)


    Phys., 40, 274-283. Feynman , R., Leighton, R., and Sands, M. 1964: The Feynman Lectures in Physics vol II, 3rd ed. Addison Wesley, 238 pp...2) This is similar to the familiar transmission line equation ( Feynman , et al, 1964) relating the gradient of the voltage along a transmission...strong function of time (skin effect) while LX is relatively insensitive to time. We attribute this to fundamental differences in the physics of the

  19. The Effects of City Image, Event Fit, and Word-of-mouth Intention towards the Host City of an International Sporting Event


    Daichi Oshimi; Munehiko Harada


    This study (1) develops a structure of host city image, (2) verifies the antecedents and consequences of host city image, and (3) predicts spectators’ positive word-of-mouth (WOM) intention towards the host city through structural equation modeling. With the cooperation of the local city government, questionnaires were distributed to spectators of the 2014 Tour de France Saitama Criterium in Japan. Convenience sampling was utilized, and 274 usable questionnaires were obtained. First, the resu...

  20. Loss and gain cycles? A longitudinal study about burnout, engagement and self-efficacy


    Susana Llorens-Gumbau; Marisa Salanova-Soria


    The present longitudinal study (two waves), conducted on a population of 274 secondary-school teachers, expands on previous research on burnout and work engagement. Accordingly, the effect of organizational factors (obstacles, facilitators) as well as personal resources (self-efficacy) on burnout and engagement is tested longitudinally following the Social Cognitive Theory. More specifically, we test the loss and gain cycles, and reciprocal relationships concerning burnout, engagement, and se...

  1. Feasibility of Epidemiologic Research on Nonauditory Health Effects of Residential Aircraft Noise Exposure. Volume 3. Summary of Literature on Cardiovascular Effects on Noise Exposure (United States)


    hypotension, etc.), nervous diseases (neuritis, asthenic states), and gastro- intestinal diseases (gastric and duodenal ulcers, gastritis ). Clinical exams...1 household noise exposure (Le, 8 h)+ 3.7 in a sitting position articles , 1 levels (Leq): + 101og T/To for 274 after 20 min rest. BP plastics, and 13...Diseases of and 51.9% em- nasopharynx, gastritis , ployed a 5 yrs. ulcers, and myositis Unstated number also studied. in control group of fitters

  2. Domain Modeling: NP_001034464.1 [SAHG[Archive

    Lifescience Database Archive (English)

    Full Text Available NP_001034464.1 chr20 Crystal structure of putative methyltransferase (YP_321342.1) ...from Anabaena variabilis ATCC 29413 at 1.90 A resolution p3ccfa_ chr20/NP_001034464.1/NP_001034464.1_holo_71-283.pdb psi-blast 131L,134H,135W,160M,161F,166L,189S,191F,273Y,274Q BEZ 0 ...

  3. Understanding Mobile Code and Secure Execution Environments (United States)


    Lecture Notes in Computer Science . Springer-Verlag, 2003. " agents. In Secure Internet Programming, number 1603 in Lecture Notes in Computer Science , pages 261-274. Springer-Verlag Inc., New York, NY, USA...cryptography. In M. Joye, editor, Topics in Cryptography-CT-RSA 󈧇, volume 2612 of Lecture Notes in Computer Science . Springer-Verlag, 2003. [5] Carl

  4. Domain Modeling: NP_937793.1 [SAHG[Archive

    Lifescience Database Archive (English)

    Full Text Available NP_937793.1 chr5 Crystal structure of putative arylsulfatase from escherichia coli p3ed4d_ chr5/NP_937793....1/NP_937793.1_holo_20-459.pdb blast 52S,53Q,54V,261K,274N,275I,276R,421T,422N,424W,455K,456F,457P,458E,459I UNL 0 ...

  5. Evaluation of buffy-coat microscopy for the early diagnosis of bacteraemia.


    Coppen, M. J.; Noble, C J; Aubrey, C


    Three hundred and sixty samples of blood from 230 hospital patients were examined and compared with the results of simultaneous blood culture to determine the value of buffy-coat microscopy in detecting bacteraemia. One observer found 86 positive smears, 12 of which were from patients with positive blood cultures and 74 from patients with negative blood cultures. The buffy-coat smear was negative in 274 specimens, 8 of which yielded positive blood cultures. A second observer considered that o...

  6. References to the paraphilias and sexual crimes in the Bible. (United States)

    Aggrawal, Anil


    While writing a book on paraphilias, the author made a thorough search of early references to paraphilias in literature, especially the Bible. Surprisingly just one published paper was available in the literature having any discussion on the references of paraphilia in the Bible, and that too was in French. [Bieder J. The polymorphous sexual deviant: a reading of Freud and the Bible. Ann Med Psychol (Paris) 1973;2(2):274-81 [in French

  7. Works notice

    CERN Multimedia

    GS Department


    We would like to inform you that renovation work on the road lighting equipment will take place on the Meyrin site between 19 October and 18 December 2009. During this period, traffic will be disrupted on the Schrödinger, Perrin and Siegbahn roads, ie from Building 274 to Building 188. We request that you comply with the road signs and thank you for your understanding. GS-SEM Group

  8. 17 CFR 270.30a-2 - Certification of Form N-CSR and Form N-Q. (United States)


    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Certification of Form N-CSR... Form N-CSR and Form N-Q. (a) Each report filed on Form N-CSR (§§ 249.331 and 274.128 of this chapter... must include certifications in the form specified in Item 12(a)(2) of Form N-CSR or Item 3 of Form...

  9. Organizational and Systems Theory: An Integrated Review (United States)


    because it was this type with which Darwin was concerned in his studies of biological species as systems. Numerous authors--including Ashby (1960), Marney...bases of social power. In D. Cartwright (Ed.), Studies in social ower. Ann Arbor: University of Michigan Institut for Social Research, 1959...N •274 2* 4" * *.* * .*I Guetzkow, H. E. Differentittion of roles in task-oriented tasks. In D. Cartwright , a’ A. Zander (jEds.), GrouT dynamics

  10. A National Strategy for an Uncertain Future (United States)


    Introduction by Samuel B. Griffith, (London: Oxford University Press, 1963), p. 84. 2. Robert W. Komer, "Thinking About Strategy: A Practitioner’ US Strategy ed. Frank R. Barnett, B. Hugh Tovar , and Richard H. Shultz (Washington: National Defense University Press, 1984), p. 274. 6. Brian M...and with an Introduction by Samuel B. Griffith (London: Oxford University Press, 1963), p. 77. 18. Belisarius, 505-565. 74 .*. .•*r¶ •-"r

  11. Reactions of H2O3 in the pulse-irradiated Fe(II)-O2 system

    DEFF Research Database (Denmark)

    Sehested, Knud; Bjergbakke, Erling; Lang Rasmussen, O.;


    G(Fe(III)] is measured in pulse-irradiated O2-saturated solutions of 20 to 160 μMFe(II), at the p H's 0.46, 1.51, and 2.74 H2SO4 and HClO4 and with dose rates between 1 and 8 krad/1 μsec pulse. Based on homogeneous kinetics, the results are interpreted by a system of 18 reactions. The formation...

  12. Biotechnology Symposium (United States)


    implant device is dependent in large part upon the quality and vitality of bone remodelling around the bone postop- ACETABULUM eratively. Bone resorption...Model of the Residual Strength and Life of Fatigue-loaded Composite Coupons," Composite Materials: Fatigue and Fracture . STP 907, H.T. Hahn, ed., ASTM...Materials Fatigue and Fracture . ASTM STP 907, D.J. Wilkins, Ed 1986, pp. 274- 297. 17. Tang, J.M., and Springer, G.S., Effects of Moisture and Temperature

  13. Conserved syntenic clusters of protein coding genes are missing in birds


    Lovell, Peter V.; Wirthlin, Morgan; Wilhelm, Larry; Minx, Patrick; Lazar, Nathan H.; Carbone, Lucia; Warren, Wesley C.; Mello, Claudio V.


    Background Birds are one of the most highly successful and diverse groups of vertebrates, having evolved a number of distinct characteristics, including feathers and wings, a sturdy lightweight skeleton and unique respiratory and urinary/excretion systems. However, the genetic basis of these traits is poorly understood. Results Using comparative genomics based on extensive searches of 60 avian genomes, we have found that birds lack approximately 274 protein coding genes that are present in th...

  14. Dicty_cDB: SHA572 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available : 112 length of database: 80,480,566 effective HSP length: 17 effective length of query: 95 effective length... of database: 78,821,179 effective search space: 7488012005 effective search space used: 7488012005 T: 0 A: ... than 10.0: 0 length of query: 112 length of database: 55,409,929,374 effective HSP length: 22 effective length of query: 90 effectiv...e length of database: 54,274,350,600 effective search space: 4884691554000 effective

  15. The Intrusion of Engine Exhaust into the Passenger Areas of Recreational Power Boats (United States)


    Annapolis, Maryland. The test boat was a 34-foot Silverton sedan cruiser equipped with twin 302 CID engines with exhaust exits located on each side of the...40.60 30.14 1.42 09:36:31 51.80 41.90 30.14 2.74 -001 -000 -@00 @00 test oeat: 361 Silverton Sedan Cruiser 19:27:01 51.30 42.70 30.14 1.53 *forever

  16. Urinary albumin in space missions

    DEFF Research Database (Denmark)

    Cirillo, Massimo; De Santo, Natale G; Heer, Martina


    Proteinuria was hypothesized for space mission but research data are missing. Urinary albumin, as index of proteinuria, was analyzed in frozen urine samples collected by astronauts during space missions onboard MIR station and on ground (control). Urinary albumin was measured by a double antibody...... radioimmunoassay. On average, 24h urinary albumin was 27.4% lower in space than on ground; the difference was statistically significant. Low urinary albumin excretion could be another effect of exposure to weightlessness (microgravity)....

  17. Ultrathin, Lightweight, and Wearable Li-O2 Battery with High Robustness and Gravimetric/Volumetric Energy Density. (United States)

    Liu, Tong; Xu, Ji-Jing; Liu, Qing-Chao; Chang, Zhi-Wen; Yin, Yan-Bin; Yang, Xiao-Yang; Zhang, Xin-Bo


    An ultrathin, lightweight, and wearable Li-O2 battery with a novel segmented structure is first fabricated by employing a "break up the whole into parts" strategy. Superior battery performance including low overpotential, high specific capacity, good rate capability, excellent cycle stability, and high gravimetric/volumetric energy density (294.68 Wh kg(-1) /274.06 Wh L(-1) ) is successfully achieved even under repeatedly various deformation.

  18. Predictors of Metabolic Syndrome in the Iranian Population: Waist Circumference, Body Mass Index, or Waist to Hip Ratio?


    Mojgan Gharipour; Nizal Sarrafzadegan; Masoumeh Sadeghi; Elham Andalib; Mohammad Talaie; Davood Shafie; Esmaiel Aghababaie


    This study aimed to investigate whether body mass index (BMI), waist circumference (WC), or waist to hip ratio (WHR) could be a better predictor of metabolic syndrome and, if so, what would be the cutoff points for these surrogates to appropriately differentiate metabolic syndrome in different age and sex subgroups. Methods. The present cross-sectional study was conducted on a sample of Isfahan Cohort Study (ICS). In total, 468 individuals (194 with and 274 subjects without metabolic syndrome...

  19. Utopia Cracks and Polygons (United States)


    MGS MOC Release No. MOC2-339, 23 April 2003This Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) image shows a pattern of polygonal cracks and aligned, elliptical pits in western Utopia Planitia. The picture covers an area about 3 km (about 1.9 mi) wide near 44.9oN, 274.7oW. Sunlight illuminates the scene from the left.

  20. Challenges and opportunities for checkpoint blockade in T-cell lymphoproliferative disorders


    Phillips, Tycel; Devata, Sumana; Wilcox, Ryan A.


    The T-cell lymphoproliferative disorders are a heterogeneous group of non-Hodgkin’s lymphomas (NHL) for which current therapeutic strategies are inadequate, as most patients afflicted with these NHL will succumb to disease progression within 2 years of diagnosis. Appreciation of the genetic and immunologic landscape of these aggressive NHL, including PD-L1 (B7-H1, CD274) expression by malignant T cells and within the tumor microenvironment, provides a strong rationale for therapeutic targetin...

  1. Parallel Human and Animal Models of Blast- and Concussion-Induced Tinnitus and Related Traumatic Brain Injury (TBI) (United States)


    not be feasible without episodic representation to form a spatial environment map ( Eichenbaum , 1999). Moreover, current study is the first study to...and GABA(B) receptors in the regulation of the nucleus accumbens dopamine response to stress. Brain research. 1150, 62-8. Eichenbaum , H., 1999. The...and hyperactivity following cochlear damage. HearRes 147, 261-274. Sanderson, K.L., Raghupathi, R., Saatman, K.E., Martin , D., Miller, G., and


    Institute of Scientific and Technical Information of China (English)


    <正>20090911 Chen Junlu(Xi’an Institute of Geology and Mineral Resources,China Geological Survey,Xi’an 710054,China);Xu Xueyi Geological Features and SHRIMP U-Pb Zircon Age of the Yanwan-Yinggezui Ophiolitic M(?)lange in the Taibai Area,Westren Qinling,China(Geogolical Bulletin of China, ISSN1671-2552,CN11-4648/P,27(4),

  3. Surface Enhanced Raman Spectroscopy for the Rapid Detection and Identification of Microbial Pathogens in Human Serum (United States)


    and hydrophobic substrata at different ph values. World Journal of Microbiology and Biotechnology , 2011. 27(4): p. 887-896. 33. Bruinsma, G., H...Percival, S.L., et al., Microbiology of the skin and the role of biofilms in infection. International wound journal, 2012. 9(1): p. 14-32. 2. Geffers...laser desorption ionization–time of flight mass spectrum analysis with the saramis database. Journal of clinical microbiology , 2013. 51(3): p. 805-809





    2016 AVEL HAEZER MATANDE, NIM : B111 12 274, Tanggung Jawab Negara Terhadap Pencemaran Udara Akibat Polusi Asap Lintas Batas (Transboundary Haze Pollution) Dalam Kasus Malaysia dan Singapura di bawah bimbingan S.M.Noor selaku pembimbing I dan Birkah Latif selaku pembimbing II. Penelitian ini bertujuan untuk mengetahui dua hal: pertama, untuk mengetahui 1. Bagaimanakah dampak polusi kabut asap yang terjadi di Riau terhad...

  5. Domain Modeling: NP_005300.1 [SAHG[Archive

    Lifescience Database Archive (English)

    Full Text Available NP_005300.1 chr8 AAT-like d1xi9d_ chr8/NP_005300.1/NP_005300.1_holo_29-487.pdb blas...t 123Y,159G,160A,161S,189Y,192Y,240I,242P,244N,272D,274V,275Y,294M,310H,311S,313S,319E,323R,413Y 189Y,314K PLP 0 ...

  6. Title VI Lands Cultural Resource Management Plan Contract No. W9128F-10-P-0092 (United States)


    pendant triangles, diamonds , trapezoids, inverted "turkey tracks" and conventionalized deer, maize and tree motifs (Johnson 1969:274; Anfinson 1979:88...multiple herringbone or nested chevron motifs; or, occasionally, rainbow motifs and filled diamonds . Lip decoration is almost ubiquitous; plain lips are...edited by Stephen C. Porter , pp. 3-37. Late-Quaternary Environments of the United States, Vol. 1, edited by H. E. Wright, Jr. University of

  7. Induction of tolerance against the arthritogenic antigen with type-II collagen peptide-linked soluble MHC class II molecules (United States)

    Park, Yoon-Kyung; Jung, Sundo; Park, Se-Ho


    In murine collagen-induced arthritis (CIA), self-reactive T cells can recognize peptide antigens derived from type-II collagen (CII). Activation of T cells is an important mediator of autoimmune diseases. Thus, T cells have become a focal point of study to treat autoimmune diseases. In this study, we evaluated the efficacy of recombinant MHC class II molecules in the regulation of antigen-specific T cells by using a self peptide derived from CII (CII260-274; IAGFKGEQGPKGEPG) linked to mouseI-Aq in a murine CIA model. We found that recombinant I-Aq/CII260-274 molecules could be recognized by CII-specific T cells and inhibit the same T cells in vitro. Furthermore, the development of CIA in mice was successfully prevented by in vivo injection of recombinant I-Aq/CII260-274 molecules. Thus, treatment with recombinant soluble MHC class II molecules in complex with an immunodominant self-peptide might offer a potential therapeutic for chronic inflammation in autoimmune disease such as rheumatoid arthritis. [BMB Reports 2016; 49(6): 331-336 PMID:26779996

  8. Oxygen and hydrogen ion abundance in the near-Earth magnetosphere: Statistical results on the response to the geomagnetic and solar wind activity conditions

    CERN Document Server

    Kronberg, Elena A; Daly, Patrick W; Grigorenko, Elena E; Kistler, Lynn; Fränz, Markus; Dandouras, Iannis


    The composition of ions plays a crucial role for the fundamental plasma properties in the terrestrial magnetosphere. We investigate the oxygen-to-hydrogen ratio in the near-Earth magnetosphere from -10 RE274 keV O+ ion intensities, relative to the corresponding hydrogen intensities; (3) In contrast to ~10 keV ions, the >274 keV O+ ions show the strongest acceleration during growth phase and not during the expansion phase itself. This suggests a connection between the energy input to the magnetosphere and the effective energization of energetic ions during growth phase; (4) The ratio between quiet and disturbed times for the intensities of ion ionospheric outflow is similar to those observed in the near-Earth magnetosphere at >274 keV. Therefore, the increase of the energetic ion intensity during disturbed time is more likely due to the intensification than to the more effective acceleration of the ionospheric source. In conclusion, the energization process in the near-Earth magnetosphere is mass dependent and...

  9. Measurement of the Survival Probabilities for Hot Fusion Reactions

    CERN Document Server

    Yanez, R; Yao, L; Barrett, J s; Zhu, S; Back, B B; Khoo, T L; Alcorta, M; Albers, M


    We have studied the fission-neutron emission competition in highly excited $^{274}$Hs (Z=108) (where the fission barrier is due to shell effects) formed by a hot fusion reaction. Matching cross bombardments ($^{26}$Mg + $^{248}$Cm and $^{25}$Mg + $^{248}$Cm) were used to identify the properties of first chance fission of $^{274}$Hs. A Harding-Farley analysis of the fission neutrons emitted in the $^{25,26}$Mg + $^{248}$Cm was performed to identify the pre- and post-scission components of the neutron multiplicities in each system. ($\\Gamma$$_{n}$/$\\Gamma$$_{t}$) for the first chance fission of $^{274}$Hs (E$^{\\ast}$ = 63 MeV) is 0.89 $\\pm$ 0.13, i.e., $\\sim$ 90 $%$ of the highly excited nuclei survive.The high value of that survival probability is due to dissipative effects during de-excitation. A proper description of the survival probabilities of excited superheavy nuclei formed in hot fusion reactions requires consideration of both dynamic and static (shell-related) effects.

  10. Templated Aggregation of TAR DNA-binding Protein of 43 kDa (TDP-43) by Seeding with TDP-43 Peptide Fibrils. (United States)

    Shimonaka, Shotaro; Nonaka, Takashi; Suzuki, Genjiro; Hisanaga, Shin-Ichi; Hasegawa, Masato


    TAR DNA-binding protein of 43 kDa (TDP-43) has been identified as the major component of ubiquitin-positive neuronal and glial inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Aggregation of TDP-43 to amyloid-like fibrils and spreading of the aggregates are suggested to account for the pathogenesis and progression of these diseases. To investigate the molecular mechanisms of TDP-43 aggregation, we attempted to identify the amino acid sequence required for the aggregation. By expressing a series of deletion mutants lacking 20 amino acid residues in the C-terminal region in SH-SY5Y cells, we established that residues 274-313 in the glycine-rich region are essential for aggregation. In vitro aggregation experiments using synthetic peptides of 40 amino acids from this sequence and adjacent regions showed that peptides 274-313 and 314-353 formed amyloid-like fibrils. Transduction of these fibrils induced seed-dependent aggregation of TDP-43 in cells expressing wild-type TDP-43 or TDP-43 lacking nuclear localization signal. These cells showed different phosphorylated C-terminal fragments of TDP-43 and different trypsin-resistant bands. These results suggest that residues 274-353 are responsible for the conversion of TDP-43 to amyloid-like fibrils and that templated aggregation of TDP-43 by seeding with different peptides induces various types of TDP-43 pathologies, i.e. the peptides appear to act like prion strains.

  11. Glycogen synthase kinase 3 β activity is required for hBora/Aurora A-mediated mitotic entry. (United States)

    Lee, Yu-Cheng; Liao, Po-Chi; Liou, Yih-Cherng; Hsiao, Michael; Huang, Chi-Ying; Lu, Pei-Jung


    The synthesis and degradation of hBora is important for the regulation of mitotic entry and exist. In G 2 phase, hBora can complex with Aurora A to activate Plk1 and control mitotic entry. However, whether the post-translational modification of hBora is relevant to the mitotic entry still unclear. Here, we used the LC-MS/MS phosphopeptide mapping assay to identify 13 in vivo hBora phosphorylation sites and characterized that GSK3β can interact with hBora and phosphorylate hBora at Ser274 and Ser278. Pharmacological inhibitors of GSK3β reduced the retarded migrating band of hBora in cells and diminished the phosphorylation of hBora by in vitro kinase assay. Moreover, as well as in GSK3β activity-inhibited cells, specific knockdown of GSK3β by shRNA and S274A/S278 hBora mutant-expressing cells also exhibited the reduced Plk1 activation and a delay in mitotic entry. It suggests that GSK3β activity is required for hBora-mediated mitotic entry through Ser274 and Ser278 phosphorylation.

  12. Toxicity evaluation of prodigiosin from Serratia marcescens in a Caenorhabditis elegans model (United States)

    Seah, Siew-Wei; Nathan, Sheila; Wan, Kiew-Lian


    Serratia marcescens produces several secondary metabolites, including a red antimicrobial pigment, prodigiosin. There is considerable interest in prodigiosin and its derivatives due to their anticancer and immunosuppressive properties. Prodigiosin has also become the main choice of red dye in textiles. As prodigiosin has potentially high commercial value, there is a demand to develop high-throughput and cost-effective bioprocesses for prodigiosin production. However little is still known about its toxicity. This study was carried out to investigate the toxicity effect of prodigiosin. To determine if prodigiosin was potentially toxic to eukaryotic systems, the S. marcescens ATCC 274 wild type (Sma 274) and the non-prodigiosin producer S. marcescens Bizio WF mutant ATCC 29635 (WF mutant) were grown under the optimised conditions for prodigiosin production and fed to the nematode Caenorhabditis elegans. The mean time to death (TDmean) for Sma 274-infected worms assayed on agar was 112.6 hours while the WF mutant culture had a TDmean of 104.4 hours. However, the nematode killing kinetics were not significantly different between the prodigiosin-producing and non-producing S. marcescens strains (p>0.05). In lieu of its non-toxic property, prodigiosin has the potential to be developed for safe therapeutic applications and as a safe environmental friendly bio-dye.

  13. Alternating Hemiplegia of Childhood mutations have a differential effect on Na(+),K(+)-ATPase activity and ouabain binding. (United States)

    Weigand, Karl M; Messchaert, Muriël; Swarts, Herman G P; Russel, Frans G M; Koenderink, Jan B


    De novo mutations in ATP1A3, the gene encoding the α3-subunit of Na(+),K(+)-ATPase, are associated with the neurodevelopmental disorder Alternating Hemiplegia of Childhood (AHC). The aim of this study was to determine the functional consequences of six ATP1A3 mutations (S137Y, D220N, I274N, D801N, E815K, and G947R) associated with AHC. Wild type and mutant Na(+),K(+)-ATPases were expressed in Sf9 insect cells using the baculovirus expression system. Ouabain binding, ATPase activity, and phosphorylation were absent in mutants I274N, E815K and G947R. Mutants S137Y and D801N were able to bind ouabain, although these mutants lacked ATPase activity, phosphorylation, and the K(+)/ouabain antagonism indicative of modifications in the cation binding site. Mutant D220N showed similar ouabain binding, ATPase activity, and phosphorylation to wild type Na(+),K(+)-ATPase. Functional impairment of Na(+),K(+)-ATPase in mutants S137Y, I274N, D801N, E815K, and G947R might explain why patients having these mutations suffer from AHC. Moreover, mutant D801N is able to bind ouabain, whereas mutant E815K shows a complete loss of function, possibly explaining the different phenotypes for these mutations.

  14. Odd-Z Transactinide Compound Nucleus Reactions Including the Discovery of 260Bh

    Energy Technology Data Exchange (ETDEWEB)

    Nelson, Sarah L. [Univ. of California, Berkeley, CA (United States)


    Several reactions producing odd-Z transactinide compound nuclei were studiedwith the 88-Inch Cyclotron and the Berkeley Gas-Filled Separator at the Lawrence Berkeley National Laboratory. The goal was to produce the same compound nucleus ator near the same excitation energy with similar values of angular momentum via differentnuclear reactions. In doing so, it can be determined if there is a preference in entrancechannel, because under these experimental conditions the survival portion of Swiatecki, Siwek-Wilcznska, and Wilczynski's"Fusion By Diffusion" model is nearly identical forthe two reactions. Additionally, because the same compound nucleus is produced, theexit channel is the same. Four compound nuclei were examined in this study: 258Db, 262Bh, 266Mt, and 272Rg. These nuclei were produced by using very similar heavy-ion induced-fusion reactions which differ only by one proton in the projectile or target nucleus (e.g.: 50Ti + 209Bi vs. 51V + 208Pb). Peak 1n exit channel cross sections were determined for each reaction in each pair, and three of the four pairs' cross sections were identical within statistical uncertainties. This indicates there is not an obvious preference of entrancechannel in these paired reactions. Charge equilibration immediately prior to fusionleading to a decreased fusion barrier is the likely cause of this phenomenon. In addition to this systematic study, the lightest isotope of element 107, bohrium, was discovered in the 209Bi(52Cr,n) reaction. 260Bh was found to decay by emission of a 10.16 MeV alpha particle with a half-life of 35$+19\\atop{-9}$ ms. The cross section is 59 pb at an excitation energy of 15.0 MeV. The effect of the N = 152 shell is also seen in this isotope's alpha particle energy, the first evidence of such an effect in Bh. All reactions studied are also compared to model predictions by Swiatecki

  15. Developments for transactinide chemistry experiments behind the gas-filled separator TASCA

    Energy Technology Data Exchange (ETDEWEB)

    Even, Julia


    synthesised carbonyl complexes were identified by nuclear decay spectroscopy. Some complexes were studied with isothermal chromatography or thermochromatography methods. The chromatograms were compared with Monte Carlo Simulations to determine the adsorption enthalpyrnon silicon dioxide and on gold. These simulations based on existing codes, that were modified for the different geometries of the chromatography channels. All observed adsorption enthalpies (on silcon oxide as well as on gold) are typical for physisorption. Additionally, the thermalstability of some of the carbonyl complexes was studied. This showed that at temperatures above 200 C therncomplexes start to decompose. It was demonstrated that carbonyl-complex chemistry is a suitable method to study rutherfordium, dubnium, seaborgium, bohrium, hassium, and meitnerium. Until now, only very simple, thermally stable compounds have been synthesized in the gas-phase chemistry of the transactindes. With the synthesis of transactinide-carbonyl complexes a new compound class would be discovered. Transactinide chemistry would reach the border between inorganic and metallorganic chemistry. Furthermore, the in-situ synthesised carbonyl complexes would allow nuclear spectroscopy studies under low background conditions making use of chemically prepared samples. [German] Die vorliegende Arbeit befasst sich mit der Entwicklung von Experimenten hinter dem gasgefuellten Separator TASCA (TransActinide Separator and Chemistry Apparatus) zur Studie des chemischen Verhaltens der Transactinide. Zum einen wurde die Moeglichkeit der elektrochemischen Abscheidung kurzlebiger Isotope der Elemente Ruthenium und Osmium auf Goldelektroden im Hinblick auf ein Experiment mit Hassium untersucht. Aus der Literatur ist bekannt, dass bei der elektrochemischen Abscheidung einzelner Atome das Abscheidepotential signifikant vom Nernst-Potential abweicht. Die Verschiebung des Potentials haengt von der Adsorptionsenthalpie des abzuscheidenden Elements

  16. A 26-year clinical observation of splenic auto-transplantation and oesophageal transection anastomosis: a new treatment strategy in patients with portal hypertension

    Institute of Scientific and Technical Information of China (English)

    ZHANG Lei; CHEN Ji-sheng; HUO Jin-shan; ZHANG Hong-wei; CHEN Ru-fu; ZHANG Jie; Obetien Mapudengo; FANG Tian-lin; CHEN Ya-jin; OU Qing-jia


    Background Surgical treatment options for patients with cirrhosis and portal hypertension are complicated. In this study,we evaluated the effectiveness of a new treatment strategy, splenic auto-transplantation and oesophageal transection anastomosis. We report results from clinical observations, splenic immune function and portal dynamics in 274 patients.Methods From 1979 to 2005, 274 cirrhosis patients with portal hypertension underwent the new treatment strategy, and were followed up to compare results with those patients who underwent traditional surgical treatment. From 1999 to 2002,a randomized controlled trial (RCT) was performed on 40 patients to compare their post-operative immune function. From 1994 to 2006, another RCT enrolled 28 patients to compare portal dynamics using three-dimensional dynamic contrast-enhanced magnetic resonance angiography (3D DEC MRA) investigation post operation.Results Among 274 patients (mean age 41.8 years), the emergency operative mortality (4.4%), selective operative mortality (2.2%), complication rate (17.9%), prevalence of hepatic encephalopathy (<1%), rate of portal hypertension gastritis (PHG) bleeding (9.1%), and morbidity of hepatic carcinoma (8%) were similar to those patients undergoing traditional operation; the spleen immunology function (Tuftsin, IgM) decreased in both groups 2 months post operation,but this decrease did not reach statistical significance. Through 3D DCE MRA, the cross sectional area and the velocity and volume of blood flow of the main portal vein decreased significantly after operation in both groups. The velocity and volume of blood flow in the auto-transplantation group was significantly lower than that in the control group.Conclusions Splenic auto-transplantation and esophageal transection anastomosis is a safe, effective, and reasonable treatment strategy for patients with portal hypertension with varicial bleeding. It not only can correct hypersplenism, but may also achieve complete

  17. Autosomal recessive transmission of a rare KRT74 variant causes hair and nail ectodermal dysplasia: allelism with dominant woolly hair/hypotrichosis.

    Directory of Open Access Journals (Sweden)

    Doroteya Raykova

    Full Text Available Pure hair and nail ectodermal dysplasia (PHNED comprises a heterogeneous group of rare heritable disorders characterized by brittle hair, hypotrichosis, onychodystrophy and micronychia. Autosomal recessive (AR PHNED has previously been associated with mutations in either KRT85 or HOXC13 on chromosome 12p11.1-q14.3. We investigated a consanguineous Pakistani family with AR PHNED linked to the keratin gene cluster on 12p11.1 but without detectable mutations in KRT85 and HOXC13. Whole exome sequencing of affected individuals revealed homozygosity for a rare c.821T>C variant (p.Phe274Ser in the KRT74 gene that segregates AR PHNED in the family. The transition alters the highly conserved Phe274 residue in the coil 1B domain required for long-range dimerization of keratins, suggesting that the mutation compromises the stability of intermediate filaments. Immunohistochemical (IHC analyses confirmed a strong keratin-74 expression in the nail matrix, the nail bed and the hyponychium of mouse distal digits, as well as in normal human hair follicles. Furthermore, hair follicles and epidermis of an affected family member stained negative for Keratin-74 suggesting a loss of function mechanism mediated by the Phe274Ser substitution. Our observations show for the first time that homozygosity for a KRT74 missense variant may be associated with AR PHNED. Heterozygous KRT74 mutations have previously been associated with autosomal dominant woolly hair/hypotrichosis simplex (ADWH. Thus, our findings expand the phenotypic spectrum associated with KRT74 mutations and imply that a subtype of AR PHNED is allelic with ADWH.

  18. Splenic autotransplantation and oesophageal transection anastomosis in patients with portal hypertension(26 years clinical observation)

    Institute of Scientific and Technical Information of China (English)

    CHEN Jisheng; HUO Jinshan; ZHANG Hongwei; SHANG Changzhen; CHEN Rufu; ZHANG Jie; Obetien Mapudengo; CHEN Yajin; ZHANG Lei


    The surgical treatment methods for cirrhosis patients complicated with portal hypertension are complicated.In this study,we evaluated the effectiveness of a new treatment strategy:splenic auto-transplantation and oesophageal transection anastomosis on 274 patients from three aspects:clinical observation,splenic immunology and portal dynamics.From 1979 to 2005,274 cirrhosis patients with portal hypertension who underwent the new treatment strategy were followed up to observe different clinical indexes,which were then compared with those of the traditional surgery treatment.From 1999 to 2002,a randomized control trial (RCT) was performed on 40 patients to compare their immune function after operation.From 1994 to 2004,another RCT.was carried out on 28 patients to compare the portal dynamics through three-dimensional dynamic contrast enhanced MR angiography (3D DEC MR.A) investigation after operation.Among 274 patients (mean age 41.8 years),the emergency operative mortality (4.4%),selective operative mortality (2.2%),complication rate (17.9%),morbidity of hepatic encephalopathy ( < 1%),bleeding rate of portal hypertension gastritis (PHG) (9.1%),and morbidity of hepatic carcinoma (8%) were similar to those under traditional operation;the spleen immunology function (Tuftsin,IgM)decreased among the groups 2 months after operation.Through 3D DCE MRA,the cross section area,the velocity and volume of blood flow of main portal vein decrease significantly after operation in both groups,the auto transplantation group was significantly lower in velocity and volume of blood flow than in the control group.Splenic auto transplantation and esophageal transection anastomosis are a safe,effective,and reasonable treatment strategy for portal hypertension with varicial bleeding.It can not only correct hypersplenism but also completely stanch blood,and auto transplanted spleen in the retroperitoneal space can preserve immune function and establish abroad collateral circulation.

  19. Presence and molecular characterisation of Giardia and Cryptosporidium in alpacas (Vicugna pacos) from Peru. (United States)

    Gómez-Couso, Hipólito; Ortega-Mora, Luis M; Aguado-Martínez, Adriana; Rosadio-Alcántara, Raúl; Maturrano-Hernández, Lenin; Luna-Espinoza, Luis; Zanabria-Huisa, Víctor; Pedraza-Díaz, Susana


    The presence of Giardia and Cryptosporidium was investigated in 274 faecal samples of alpacas (Vicugna pacos) from 12 herds from Peru by immunofluorescence microscopy and PCR amplification and sequencing of fragments of the ssu-rRNA and β-giardin genes from Giardia spp., as well as the ssu-rRNA gene from Cryptosporidium spp. A total of 137 samples (50.0%) were positive for Giardia spp., and 12 samples (4.4%) for Cryptosporidium spp. In ten samples (3.6%), co-infection by both pathogens was found. Herd prevalence was found to be 91.7% (11/12 herds) for Giardia and 58.3% (7/12 herds) for Cryptosporidium. Regarding the age of the animals, although Giardia was detected in animals as young as 1 week, the prevalence increased with age, reaching 80% by 8 weeks. Similarly, the highest percentage of Cryptosporidium detection (20%) was also found in the 8 week-old group. By PCR, 92 of the 274 analysed samples were positive for Giardia. Sequencing of the amplicons showed the existence of Giardia duodenalis assemblage A in 67 samples; G. duodenalis assemblage E in 24 samples; and inconsistent results between the two molecular markers used in a further sample. Cryptosporidium was only detected by PCR in 3 of the 274 samples; Cryptosporidium parvum was identified in two samples and Cryptosporidium ubiquitum in one sample. This study is the first performing molecular characterisation of both parasites in Peruvian alpacas, and the first report of C. ubiquitum in this host. The identification of G. duodenalis assemblage A, C. parvum and C. ubiquitum, suggests that zoonotic transmission of these enteropathogens between alpacas and humans is possible.

  20. Community-based Disease Management Model for Chronic Heart Failure%慢性心力衰竭社区疾病管理模式探索

    Institute of Scientific and Technical Information of China (English)

    单红; 练宇; 刘振芳; 范文娟; 郭莹; 彭翔; 彭建强; 冯洁; 唐铭翔; 颜素岚; 谢琼; 邹琼超; 傅庆华


    Objective To understand the characteristics of people with chronic heart failure in community,based on which to make the suitable community management of the disease,next to discuss whether patients with chronic heart failure can benefit from the community management or not,so as to provides a new way for comprehensive prevention of chronic heart fail-ure. Methods (1) Self-designed questionnaire was used to investigate 288 patients with chronic heart failure in Liufu Street community of Changsha from March to April in 2012 who volunteered to take part in the community management about the charac-teristics of heart failure population. (2) Self-designed systematic management methods of chronic heart failure disease was used to interfere another 200 patients in the community drug treatment from May 2012 to May 2013,health education,lifestyle,self-management,etc. Patients' basic indexes controlling situation,usage rate of heart failure conventional drugs,awareness rate of heart failure knowledge,self-management,MNLF scores,frequency of hospitalization and incidence of cardiovascular events were observed before and after the intervention. Results (1)288 questionnaire were sent out,receiving 279 questionnaires with a recovering rate of 96. 88% and 274 valid questionnaires with an effective rate of 98. 21%. The average age of the patients was(68. 7 ± 10. 6);MNLF score was(22. 13 ± 14. 64);68. 61%(188/274)of the patients had low salt and low fat diets;41. 97%(115/274)measured their blood pressure on a regular basis;the control rate of blood pressure was 35. 40%(97/274);the active follow-up rate was 25. 18%(69/274)and the active accepting health education was 8. 03%(22/274). (2)After intervention,blood pressure control rate and heart rate control rate were higher than before(P﹤0. 05). The differ-ence of blood sugar control rate before and after intervention was not significant(P﹥0. 05). The usage rate of ACEI/ARB andβblockers,the awareness rate of heart failure

  1. Clonal dissemination, emergence of mutator lineages and antibiotic resistance evolution in Pseudomonas aeruginosa cystic fibrosis chronic lung infection.

    Directory of Open Access Journals (Sweden)

    Carla López-Causapé

    Full Text Available Chronic respiratory infection by Pseudomonas aeruginosa is a major cause of mortality in cystic fibrosis (CF. We investigated the interplay between three key microbiological aspects of these infections: the occurrence of transmissible and persistent strains, the emergence of variants with enhanced mutation rates (mutators and the evolution of antibiotic resistance. For this purpose, 10 sequential isolates, covering up to an 8-year period, from each of 10 CF patients were studied. As anticipated, resistance significantly accumulated overtime, and occurred more frequently among mutator variants detected in 6 of the patients. Nevertheless, highest resistance was documented for the nonmutator CF epidemic strain LES-1 (ST-146 detected for the first time in Spain. A correlation between resistance profiles and resistance mechanisms evaluated [efflux pump (mexB, mexD, mexF, and mexY and ampC overexpression and OprD production] was not always obvious and hypersusceptibility to certain antibiotics (such as aztreonam or meropenem was frequently observed. The analysis of whole genome macrorestriction fragments through Pulsed-Field Gel Electrophoresis (PFGE revealed that a single genotype (clone FQSE-A produced persistent infections in 4 of the patients. Multilocus Sequence typing (MLST identified clone FQSE-A as the CF epidemic clone ST-274, but striking discrepancies between PFGE and MLST profiles were evidenced. While PFGE macrorestriction patterns remained stable, a new sequence type (ST-1089 was detected in two of the patients, differing from ST-274 by only two point mutations in two of the genes, each leading to a nonpreviously described allele. Moreover, detailed genetic analyses revealed that the new ST-1089 is a mutS deficient mutator lineage that evolved from the epidemic strain ST-274, acquired specific resistance mechanisms, and underwent further interpatient spread. Thus, presented results provide the first evidence of interpatient dissemination

  2. Cloning, expression, and characterization of a novel xylose reductase from Rhizopus oryzae. (United States)

    Zhang, Min; Jiang, Shao-tong; Zheng, Zhi; Li, Xing-jiang; Luo, Shui-zhong; Wu, Xue-feng


    Rhizopus oryzae is valuable as a producer of organic acids via lignocellulose catalysis. R. oryzae metabolizes xylose, which is one component of lignocellulose hydrolysate. In this study, a novel NADPH-dependent xylose reductase gene from R. oryzae AS 3.819 (Roxr) was cloned and expressed in Pichia pastoris GS115. Homology alignment suggested that the 320-residue protein contained domains and active sites belonging to the aldo/keto reductase family. SDS-PAGE demonstrated that the recombinant xylose reductase has a molecular weight of approximately 37 kDa. The optimal catalytic pH and temperature of the purified recombinant protein were 5.8 and 50 °C, respectively. The recombinant protein was stable from pH 4.4 to 6.5 and at temperatures below 42 °C. The recombinant enzyme has bias for D-xylose and L-arabinose as substrates and NADPH as its coenzyme. Real-time quantitative reverse transcription PCR tests suggested that native Roxr expression is regulated by a carbon catabolite repression mechanism. Site-directed mutagenesis at two possible key sites involved in coenzyme binding, Thr(226)  → Glu(226) and Val(274)  → Asn(274), were performed, respectively. The coenzyme specificity constants of the resulted RoXR(T226E) and RoXR(V274N) for NADH increased 18.2-fold and 2.4-fold, which suggested possibility to improve the NADH preference of this enzyme through genetic modification.

  3. ATRX binds to atypical chromatin domains at the 3' exons of zinc finger genes to preserve H3K9me3 enrichment. (United States)

    Valle-García, David; Qadeer, Zulekha A; McHugh, Domhnall S; Ghiraldini, Flávia G; Chowdhury, Asif H; Hasson, Dan; Dyer, Michael A; Recillas-Targa, Félix; Bernstein, Emily


    ATRX is a SWI/SNF chromatin remodeler proposed to govern genomic stability through the regulation of repetitive sequences, such as rDNA, retrotransposons, and pericentromeric and telomeric repeats. However, few direct ATRX target genes have been identified and high-throughput genomic approaches are currently lacking for ATRX. Here we present a comprehensive ChIP-sequencing study of ATRX in multiple human cell lines, in which we identify the 3' exons of zinc finger genes (ZNFs) as a new class of ATRX targets. These 3' exonic regions encode the zinc finger motifs, which can range from 1-40 copies per ZNF gene and share large stretches of sequence similarity. These regions often contain an atypical chromatin signature: they are transcriptionally active, contain high levels of H3K36me3, and are paradoxically enriched in H3K9me3. We find that these ZNF 3' exons are co-occupied by SETDB1, TRIM28, and ZNF274, which form a complex with ATRX. CRISPR/Cas9-mediated loss-of-function studies demonstrate (i) a reduction of H3K9me3 at the ZNF 3' exons in the absence of ATRX and ZNF274 and, (ii) H3K9me3 levels at atypical chromatin regions are particularly sensitive to ATRX loss compared to other H3K9me3-occupied regions. As a consequence of ATRX or ZNF274 depletion, cells with reduced levels of H3K9me3 show increased levels of DNA damage, suggesting that ATRX binds to the 3' exons of ZNFs to maintain their genomic stability through preservation of H3K9me3.

  4. A comparison of the effect of epidermal growth factor, platelet-derived growth factor, and fibroblast growth factor on rat periodontal ligament fibroblast-like cells' DNA synthesis and morphology

    DEFF Research Database (Denmark)

    Blom, S; Holmstrup, P; Dabelsteen, Erik


    An enhanced formation of bone, dentin, and collagen fibers in periodontal wounds after application of polypeptide growth factors has recently been reported. However, the complex environment in vivo makes it impossible to determine the specific effects of growth factors on various cells involved...... nuclei. Incorporation of [3H]-thymidine was increased in a dose-dependent manner by all growth factors. Maximal effect on the DNA synthesis was: rEGF, 131%; nPDGF, 274%; and nFGF, 182%.(ABSTRACT TRUNCATED AT 250 WORDS)...

  5. Functional Interactions Between c-Src and HER1 Potentiate Neoplastic Transformation: Implications for the Etiology of Human Breast Cancer (United States)


    Rev 12:255-274, 1983. 1544, 1989. 6. Libermann TA, Nussbaum HR, Razon N, et al. Amplification and 30. Roche S, Koegl M, Barone MV, Roussel MF...results suggest phosphorylations on the receptor (Tyr-845 and Tyr-ll01). that one mechanism by which c-Src could augment the mito - Using stable cell lines...stimulation of a mito - Enzymol. 255, 245-256. genic pathway not involving ERK2. 18. Hanks, S. J., Quinn, A. M. & Hunter, T. (1988) Science 241, These

  6. Design and analysis of dual fuel methanol-power poly-generation

    Institute of Scientific and Technical Information of China (English)

    Minghua WANG; Zheng LI; Weidou NI


    A dual fuel head poly-generation flowsheet was designed based on coal gas and coke oven gas. To help clearly understand the system performance, a 1.2×108-3.2×108 kg methanol and 274-496 MW power poly-generation system was simulated by using the commercially available software ASPEN Plus and GT Pro. The technology scheme, the operating parameters, and the efficiency of the system were also analyzed and evaluated, which will be used for building industrial devices.

  7. Extension of the Job Demands-Resources model in the prediction of burnout and engagement among teachers over time. (United States)

    Lorente Prieto, Laura; Salanova Soria, Marisa; Martínez Martínez, Isabel; Schaufeli, Wilmar


    Our purpose was to extend the Job Demand-Resources Model (Schaufeli & Bakker, 2004) by including personal resources, job demands and job resources to predict burnout (exhaustion, cynicism, depersonalization) and work engagement (vigour and dedication). The sample comprised 274 teachers from 23 secondary schools of the Valencian Community (Spain). Hierarchical multiple regression analyses have revealed: (1) the predictor effect of quantitative overload on exhaustion and dedication at T2, (2) role conflict on cynicism and (3) role ambiguity on dedication. Lastly, the mediating role of burnout and engagement at T2. Practical implications and directions of future research are discussed.

  8. The Role of GADD34 (Growth Arrest and DNA Damage-Inducible Protein) in Regulating Apoptosis, Proliferation, and Protein Synthesis in Human Breast Cancer Cells (United States)


    and Lee, E. Y. (1994) J. Biol. Chein . 269, 12. Wakula, P., Bcullena, M., Ceulemans, H,, Stalinans, W., and Bollen, M. (2003) 13766-13770 J. Biol... Chein . 271, 28478-28484 14. Conner. J. H., Kicernan, T., Banik. S., Honkanen, R. E., and Shenolikar, S. 34. Schiender, K. K., Wang, W., and Wilson, S...E. (1989) Biochem. Biophys. Res. (1999) J. Riol. Chein .. 274, 22366-22372 Commun. 159, 72-78 15. Watanabe, T., Huang, H. B., Horiuchi, A., da Cruze

  9. Analysis on relationship between Tau protein and outcome of acute intracerebral hemorrhage%血清 Tau 蛋白水平与脑出血患者早期预后的相关性分析

    Institute of Scientific and Technical Information of China (English)

    郝璞珩; 李娜; 金林; 张冬子; 贾卓鹏; 陈斌; 行治国


    Objective To explore the relationship between Tau protein and outcome of acute intracerebral hemorrhage(ICH).Methods The clinical data of 274 patients with acute ICH were analyzed retrospectively.The general informations of patients on admission, medical history, clinical data and imaging features were collected.The patients were divided into good outcome group ( GOS 4-5) and poor outcome group ( GOS 1-3 ) using the Glasgow Outcome Rating Scale ( GOS ) of discharged patients.Results Of 274 patients, 145 had a good outcome, accounting for 52.9% of the total number and 129 poor outcome, accounting for 47.1%.In poor outcome group (394.7 ± 29.6 pg/ml) initial Serum Tau protein level was significantly higher than that in the good outcome group (201.2 ±18.5pg/ml).High Tau protein level was associated with poor outcome.Conclusion In patients with acute ICH, admission high Tau protein is strong predictor of a poor prognosis.%目的:探讨血清Tau蛋白水平与脑出血( ICH)患者早期预后的关系。方法回顾性分析274例自发的脑出血患者的病历资料,收集患者入院时的一般资料、病史、临床资料以及影像学特点等指标,采用GOS评分对患者出院时情况进行评分,分为预后良好组( GOS 4~5分)和预后不良组( GOS 1~3分)。结果274例患者中145例患者预后良好,占总人数的52.9%,129例预后不良,占47.1%。预后不良组入院时血清Tau蛋白(394.7±29.6 pg/ml)明显高于预后良好组(201.2±18.5 pg/ml)。血清高Tau蛋白水平与不良预后相关。结论在ICH患者中,入院时血清高Tau蛋白水平是预后不良的强预测因素。

  10. Eighteen days of "living high, training low" stimulate erythropoiesis and enhance aerobic performance in elite middle-distance runners

    DEFF Research Database (Denmark)

    Brugniaux, Julien V; Schmitt, Laurent; Robach, Paul;


    The efficiency of "living high, training low" (LHTL) remains controversial, despite its wide utilization. This study aimed to verify whether maximal and/or submaximal aerobic performance were modified by LHTL and whether these effects persist for 15 days after returning to normoxia. Last, we tried...... of erythropoiesis in LHTL shown by the 27.4% increase in serum transferrin receptor and the 10.1% increase in total hemoglobin mass, red cell volume was not significantly increased at Post1 (+9.2%, not significant). Therefore, both maximal and submaximal aerobic performance in elite runners were increased by LHTL...

  11. Eleven new heaviest isotopes of elements Z = 105 to Z = 117 identified among the products of 249Bk+48Ca reactions

    Energy Technology Data Exchange (ETDEWEB)

    Oganessian, Yuri Ts. [FLNR-JINR, Russia; Abdullin, F. Sh. [Joint Institute for Nuclear Research, Dubna, Russia; Bailey, P. D. [Oak Ridge National Laboratory (ORNL); Benker, D. E. [Oak Ridge National Laboratory (ORNL); Bennett, M. E. [University of Nevada, Las Vegas; Dmitriev, S. [FLNR-JINR, Russia; Ezold, Julie G. [Oak Ridge National Laboratory (ORNL); Hamilton, J. H. [Vanderbilt University; Henderson, R. [Lawrence Livermore National Laboratory (LLNL); Itkis, M. G. [FLNR-JINR, Russia; Lobanov, Yu. V. [Joint Institute for Nuclear Research, Dubna, Russia; Mezentsev, A. N. [Joint Institute for Nuclear Research, Dubna, Russia; Moody, K. [Lawrence Livermore National Laboratory (LLNL); Nelson, S. L. [Lawrence Livermore National Laboratory (LLNL); Polyakov, A. N. [Joint Institute for Nuclear Research, Dubna, Russia; Porter, C. E. [Oak Ridge National Laboratory (ORNL); Ramayya, A. V. [Vanderbilt University; Riley, F. D. [Oak Ridge National Laboratory (ORNL); Roberto, James B [ORNL; Ryabinin, M. A. [Research Institute of Atomic Reactors, Dimitrovgrad, Russia; Rykaczewski, Krzysztof Piotr [ORNL; Taylor, R [Oak Ridge National Laboratory (ORNL); Tsyganov, Yu. S. [Joint Institute for Nuclear Research, Dubna, Russia; Utyonkov, V. [FLNR-JINR, Russia; Voinov, A. A. [Joint Institute for Nuclear Research, Dubna, Russia; Vostokin, G. K. [Joint Institute for Nuclear Research, Dubna, Russia; Wilk, P. A. [Lawrence Livermore National Laboratory (LLNL)


    The heaviest isotopes of elements Z = 117 to Z = 105, 294117, 293117, 290115, 289115, 286113, 285113, 282Rg, 281Rg, 278Mt, 274Bh, and 270Db, were identified by means of the Dubna gas-filled recoil separator among the products of the 249Bk + 48Ca reaction. The details of the observed six decay chains, indicating the production and decay of isotopes 293117 and 294117, are presented and discussed. The decay energies and resulting half-lives of these new nuclei show a strong rise of stability with increasing neutron number, validating the concept of the island of enhanced stability for superheavy nuclei.

  12. Clinical characteristics and consequences of hand eczema - an 8-year follow-up study of a population-based twin cohort

    DEFF Research Database (Denmark)

    Lerbaek, Anne; Kyvik, Kirsten Ohm; Ravn, Henrik;


    /METHODS: A total of 274 individuals with and without hand eczema were examined, patch tested, and interviewed in 1997-1998 and 2005-2006. Data on 188 individuals with hand eczema in 2005-2006 were analysed. RESULTS: Erythema and scaling were the most frequent symptoms, and fingers and palms were most often...... affected. Mean hand eczema severity index score in individuals with clinical symptoms was 12.0. Sick leave was reported by 12.4%; job change by 8.5%. Being in the lowest socio-economic group and atopic dermatitis were risk factors for sick leave [odds ratio (OR) = 5.6; 95% confidence interval (95% CI) 1...

  13. Allometric scales: a fair approach in process assessment in human movement sciences


    Moncada Jiménez, José; Lachowetz, Anthony


    The purpose of the study was to compare the running time in sixth graders from Costa Ricaand the United States and to investigate the influence of body mass on running time.Students (N = 274) was measured body massand time to travel 1609 m walk. Statistical analyzes included 2 x 2 factorial ANOVA (country x gender) for body mass variables and race time, andregression analysis to create an index scores adjusted race time and set aside theconfounding effect of body mass. It was found that the n...

  14. Escalas alométricas: un justo criterio en el proceso de evaluación en las ciencias del movimiento humano


    José Moncada Jiménez; Anthony Lachowetz


    El propósito del estudio fue comparar el tiempo de carrera en estudiantes de sexto grado de Costa Rica y los Estados Unidos de Norteamérica e investigar la influencia de la masa corporal sobre el tiempo de carrera. A los estudiantes (N = 274) se les midió la masa corporal y el tiempo en recorrer 1609 m a pie. Los análisis estadísticos incluyeron ANOVA factorial 2 x 2 (país x género) para las variables de masa corporal y tiempo de carrera; y un análisis de regresión par...

  15. Alternatives to the Judicially Promulgated Feres Doctrine (United States)


    assaulted an Army sergeant. Lieutenant Locke also allegedly told the team that pepper spray had failed to subdue the "detainee." The evidence suggests that...States, 248 F.3d 863, 869 (9th Cir. 2001) ( Ferguson , J., dissenting). Critics of this line of thought have pointed to the fact that, even though more...2674, 2680 (2004). 274 Costo, 248 F.3d at 871 ( Ferguson , J., dissenting). See Schoemer v. United States, 59 F.3d 26, 28 (5th Cir. 1995); Pringle v

  16. RXTE Confirms Persistent Activity of Burster IGR J17473-2721 (United States)

    Markwardt, C. B.; Altamirano, D.; Swank, J. H.; in't Zand, J.


    Following reports of bursting activity of IGR J17473-2721 (= XTE J1747-274) by the AGILE team (Del Monte et al., ATEL #1445) and from Swift (Altamirano et al., ATEL #1459), we note that RXTE PCA monitoring scans of the source also reveal persistent activity. Scans on 2008-03-28 at 18:50 UT and 2008-03-31 at 15:10 UT found 2-10 keV fluxes of about 13 and 18 mCrab, respectively. Previous scans are consistent with quiescent level (with 2-sigma upper limits ~6 mCrab).

  17. Og4C3 circulating antigen: a marker of infection and adult worm burden in Wuchereria bancrofti filariasis. (United States)

    Chanteau, S; Moulia-Pelat, J P; Glaziou, P; Nguyen, N L; Luquiaud, P; Plichart, C; Martin, P M; Cartel, J L


    Og4C3 circulating filarial antigen was detected in the sera of 94.5% (259/274) of microfilaremic patients, 32% (239/751) of persons with presumption of filariasis, and 23% (11/48) of chronic filariasis patients. The antigen level was correlated with the microfilariae (Mf) density and patient age (P < .01). It remained stable in patients treated with microfilaricidal drugs. Og4C3 antigen, undetectable in Mf culture media, was demonstrated to be a rare somatic Mf antigen. It appears to be an excreted or secreted antigen from adult filaria. It could be used as a marker of infection and an indicator of adult worm burden.

  18. An Imidazole based probe for relay recognition of Cu2+ and OH− ions leading to AND logic gate

    Indian Academy of Sciences (India)

    Navneet Kaur; Priya Alreja


    2-(2-methoxyphenyl)-4,5-diphenyl-1H-imidazole 1, an imidazole-based compound, was found to sense Cu2+ ions via fluorescence and absorption spectroscopy over a number of other metal ions. During Cu2+ sensing, the chemosensor 1 followed a “switch-off” mechanism. Job’s plot supported 1:1 stoichiometry of 1-Cu2+ complex. The 1-Cu2+ complex formed in situ underwent different absorption changes with OH− ions. These differential absorption changes observed with the addition of Cu2+ and OH− ions were used to mimic AND logic gate using A274nm as output.

  19. Breast Cancer Research Program (BCRP) - Predoctoral Traineeship - Elucidating the Role of the Type III Transforming Growth Factor-beta Receptor in Bone Morphogenetic Signaling in Breast Cancer (United States)


    A., Wiater, E., Bilez- ikjian, L. M., and Vale, W. (2000) Nature 404, 411–414 16. Blobe, G. C., Liu, X., Fang, S. J., How, T., and Lodish , H. F. (2001... Lodish , H. F., and Weinberg, R. A. (1991) Cell 67, 797–805 24. Barbara, N. P., Wrana, J. L., and Letarte, M. (1999) J. Biol. Chem. 274, 584–594 25...Pepin,M. C., Beauchemin,M.,Moustakas, A., Lodish , H. F., andO’Connor-McCourt,M.D. (2001) J. Biol. Chem. 276, 24627–24637 52. Wang, S., and Hirschberg

  20. Effects of entrance channel on fusion probability in hot fusion reactions

    CERN Document Server

    Zhu, Long; Huang, Ching-Yuan; Zhang, Feng-Shou


    Within the framework of the dinuclear system (DNS) model, the fusion reactions leading to the compound nuclei 274Hs and 286Cn are investigated. The fusion probability as a function of DNS excitation energy is studied. The calculated results are in good agreement with the available experimental data. The obtained results show that the fusion probabilities are obviously enhanced for the reactions located at high place in potential energy surface, although these reactions may have small values of mass asymmetry. It is found that the enhancement is due to the large potential energy of the initial DNS.

  1. Canada in Afghanistan: 2001-2010. A Military Chronology (United States)


    the Line of Duty;” Red Fridays, “Fallen Canadians.” 239 DND, Operation Altair. DRDC CORA CR 2010-282 41 • Charles Company was to seize the high...SchoolhousePashmulacross from the Arghandab River.241 3 September • CF Charles Company at the White Schoolhouse (Objective Rugby).242 Casualties...opium in the world).273 4 February • U.S. General Dan McNeill replaces British General David Richards as commander of NATO-ISAF.274 8.3 March 2007

  2. Traveling wave dispersal in partially sedentary age-structured populations

    CERN Document Server

    Le, Thuc Manh; Van Minh, Nguyen


    In this paper we present a thorough study on the existence of traveling waves in a mathematical model of dispersal in a partially sedentary age-structured population. This type of model was first proposed by Veit and Lewis in [{\\it Am. Nat.}, {\\bf 148} (1996), 255-274]. We choose the fecundity function to be the Beverton-Holt type function. We extend the theory of traveling waves in the population genetics model of Weinberger in [{\\it SIAM J. Math. Anal.}, {\\bf 13} (1982), 353-396] to the case when migration depends on age groups and a fraction of the population does not migrate.

  3. Traveling wave dispersal in partially sedentary age-structured biological populations

    CERN Document Server

    Le, Thuc Manh; Van Minh, Nguyen


    In this paper we present a thorough study on the existence of traveling waves in a mathematical model of dispersal in a partially sedentary age-structured population. This type of model was first proposed by Veit and Lewis in [{\\it Am. Nat.}, {\\bf 148} (1996), 255-274]. We choose the fecundity function to be the Beverton-Holt type function. We extend the theory of traveling waves in the population genetics model of Weinberger in [{\\it SIAM J. Math. Anal.}, {\\bf 13} (1982), 353-396] to the case when migration depends on age groups and a fraction of the population does not migrate.



    Bozkurt, Z.; Bayram, I; A. BÜLBÜL; O. C. AKTEPE


    Two thousand 1-day-old layer chicks were used in the study from Lohman Brown, Isa Brown, Lohman White and Bowans White breeds. The chicks were placed in the at 3 cage densities (211.8, 274.5 and 370.6 cm2 per bird) and on 3 positions (as top, middle and bottom tiers). All birds were kept under standard management policy and a commercial vaccination program was practiced. Total specific antibody titres to Infectious Brochitis Virus (IBV), Infectious Bursal Desease Virus (IBDV), Newcastle Disea...

  5. Molecular Targets for Organophosphates in the Central Nervous System (United States)


    picrotoxin (100 µM). Bottom graph: Quantification of the effects of VX (0.1 1 nM) on the peak amplitude of the evoked action to VX for 30 min. Membrane potential: –70 mV. Bottom graph: Quantification of the effect of various concentrations of VX (10 nM-1 µM) on the...Agonist actions of the novel alkaloid epibatidine and analysis of type II current. J. Pharmacol. Exp. Ther. 274:771-782, 1995. Swanson, K.L

  6. Phaeobacter grown in biofilters: a new strategy for the control of Vibrionaceae in aquaculture

    DEFF Research Database (Denmark)

    Prol García, María Jesús; Gomez, Marina; Sanchez, Lorenzo;


    Growth, biofilm formation, antagonism and residence time in green seawater tanks maintained under fish rearing conditions of Phaeobacter 27-4 were studied in commercial biofilters made from plastic, sintered glass and ceramic. Phaeobacter reached 10(8)-10(9)CFUcm(-3) and formed rosettes in all...... in one-two Log, showing 10(7)CFUmL(-1) after 24h. Phaeobacter also diminished biofilters colonization by the pathogens, both in seawater and in MB. Phaeobacter residence time in green seawater tanks maintained under fish rearing conditions was longer with sintered glass and ceramic biofilters. The latest...

  7. Spin-dependent electron momentum densities in Co{sub 2}FeGa studied by Compton scattering

    Energy Technology Data Exchange (ETDEWEB)

    Deb, Aniruddha E-mail:; Itou, M.; Sakurai, Y.; Hiraoka, N.; Sakai, N


    The spin density of Heusler alloy Co{sub 2}FeGa, has been studied using the Compton scattering technique with 274 keV circularly polarized synchrotron radiation in the high energy inelastic scattering beamline (BL08W), at SPring-8, Japan. The magnetic Compton profiles along the two principal directions [1 1 0] and [1 1 1] were measured. The spin profiles shows a good agreement with our FLAPW-GGA results, where the theoretical results were based on the ferromagnetic ground state. The 3d spin moment at the Co and the Fe site was found to be in excellent agreement with the earlier reported neutron diffraction measurements. (author)

  8. Gambling on the Lottery: Sociodemographic Correlates Across the Lifespan



    Two representative U.S. telephone surveys of gambling were conducted --an adult survey of adults aged 18 years and older (n = 2,631) and a youth survey of young people aged 14 – 21 years old (n = 2,274). Because the questions and methods were the same or similar in both surveys, the data from these two surveys were combined into a single dataset to examine the prevalence and sociodemographic correlates of gambling and problem gambling across the lifespan. The present work focused specifically...

  9. Symptoms of depression in people with impaired glucose metabolism or Type 2 diabetes mellitus

    DEFF Research Database (Denmark)

    Adriaanse, M C; Dekker, J M; Heine, R. J.


    OBJECTIVE: To study the prevalence and risk factors of depressive symptoms, comparing subjects with normal glucose metabolism (NGM), impaired glucose metabolism (IGM) or Type 2 diabetes mellitus (DM2). RESEARCH DESIGN AND METHODS: Cross-sectional data from a population-based cohort study conducted...... among 550 residents (276 men and 274 women) of the Hoorn region, the Netherlands. Levels of depressive symptoms were measured using the Centre for Epidemiologic Studies Depression Scale (CES-D score > or = 16). Glucose metabolism status was determined by means of fasting and post-load glucose levels...

  10. Platelet Function in Basset Hound Hereditary Thrombopathy. (United States)


    Hematol, 17(4),242-258, 1980. 5. CHARO, I.F., FEINMAN , R.D., DETWILER, T.C. Interrelation of platelet aggregation and secretion. J. Clin. Invest...of dogs affected with Basset Hound Hereditary Thrombopathy. Thromb Au, 3, 61-71, 1985. 4. DETWILER, T.C., CHARO, I.F., AND FEINMAN , R.D. Evidence...glycoproteins. Surv Synth Path Res 1:274, 1983. Charo IF, Feinman RD, and Detwiler TC. Interrelation of platelet aggregation and secretion. J Clin Invest 60

  11. Propfan Test Assessment (PTA): Flight test report (United States)

    Little, B. H.; Bartel, H. W.; Reddy, N. N.; Swift, G.; Withers, C. C.; Brown, P. C.


    The Propfan Test Assessment (PTA) aircraft was flown to obtain glade stress and noise data for a 2.74m (9 ft.) diameter single rotation propfan. Tests were performed at Mach numbers to 0.85 and altitudes to 12,192m (40,000 ft.). The propfan was well-behaved structurally over the entire flight envelope, demonstrating that the blade design technology was completely adequate. Noise data were characterized by strong signals at blade passage frequency and up to 10 harmonics. Cabin noise was not so high as to preclude attainment of comfortable levels with suitable wall treatment. Community noise was not excessive.

  12. 78 FR 41016 - Preliminary Theft Data; Motor Vehicle Theft Prevention Standard (United States)


    ... 35,638 1.1224 63 KIA SPORTAGE 50 45,604 1.0964 64 NISSAN INFINITI M37/M56.. 16 14,818 1.0798 65 BMW 7......... LINCOLN MKT....... 4 4,274 0.9359 73 VOLVO S80 4 4,281 0.9344 74 BMW M3 7 7,575 0.9241 75 GENERAL MOTORS....8182 91 BMW B7 10 12,493 0.8005 92 GENERAL MOTORS..... BUICK LACROSSE/ 49 62,533 0.7836 ALLURE. 93...

  13. Chalcones as novel influenza A (H1N1) neuraminidase inhibitors from Glycyrrhiza inflata

    DEFF Research Database (Denmark)

    Dao, Trong Tuan; Nguyen, Phi Hung; Lee, Hong Sik;


    The emergence of highly pathogenic influenza A virus strains, such as the new H1N1 swine influenza (novel influenza), represents a serious threat to global human health. During our course of an anti-influenza screening program on natural products, one new licochalcone G (1) and seven known (2......-8) chalcones were isolated as active principles from the acetone extract of Glycyrrhiza inflata. Compounds 3 and 6 without prenyl group showed strong inhibitory effects on various neuraminidases from influenza viral strains, H1N1, H9N2, novel H1N1 (WT), and oseltamivir-resistant novel H1N1 (H274Y) expressed...

  14. Preliminary crystallographic analysis of a cruciferin protein from seeds of Moringa oleifera. (United States)

    Akrem, Ahmed; Yousef, Nasser; Begum, Afshan; Negm, Amr; Meyer, Arne; Perbandt, Markus; Buck, Friedrich; Betzel, Christian


    A 55 kDa cruciferin protein has been purified and characterized from seeds of Moringa oleifera plant. Protein blast of N-terminal amino-acid sequence showed 60 % sequence similarity with cruciferin from Brassica napus. The M. oleifera protein has been crystallized applying the sitting drop method using 5 % polyethylene glycol 8,000, 38.5 % 3-methyl-1,5-pentanediol and 0.1 M sodium cacodylate pH 6.5. The crystals belonged to the P6322 hexagonal space group with cell dimensions, a = b = 98.4, c = 274.3 Å. Initial diffraction data have been collected to a resolution of 6 Å.

  15. Flavonols (kaempeferol, quercetin, myricetin) contents of selected fruits, vegetables and medicinal plants. (United States)

    Sultana, Bushra; Anwar, Farooq


    The concentrations of flavonols (kaempeferol, quercetin, myricetin) were determined in 22 plant materials (9 vegetables, 5 fruits, and 8 medicinal plant organs). The materials were extracted with acidified methanol (methanol/HCl, 100:1, v/v) and analyzed by reverse phase high-performance liquid chromatographic (RP-HPLC) with UV detection. The total flavonols contents varied significantly (Paloe vera leaves contained the highest contents of flavonols (6125.6 and 1636.04mgkg(-1)), respectively, whereas, lowest was present in barks (2.42-274.07mgkg(-1)). Overall, leafy green vegetables, soft fruits and medicinal plant leaves exhibited higher levels of flavonols.

  16. Concurrent Breakpoints (United States)


    and raytracer from the Java Grande Fo- rum [16]; and Jigsaw, W3C’s leading-edge Web server platform. For Jigsaw, we used a test harness that simulates...notify1 stall 1.00 Meth. II raytracer 1860 1.097 1.274 16.1 race1 test fail 1.00 1.196 9.0 race2 test fail 1.00 1.360 24.0 race3 1.00 1.428 30.2

  17. Aerial Reconnaissance Binoculars (United States)


    199212 Z= 8,51005 L= 0 M= 204139-4 N= . Table 1.2 Marginal ray height for zero degroos Ineldont rayo YO= .6 X ) Y= .60795 Z= 3-96631E-p X 0 Y= high vibration environments where standard military binoculars (7 x 50) are only marginally helpful to the naked eye in the detection of targets...of-view 17.8 degrees Exit Pupil 9.65 mm Eye Relief 274 mm Size 4.5 x 8.75 x 3.5 inches Weight 4.3 lbs 3 2. Computer Design - Ray Tracing of Original

  18. Synthesis and Preliminary Properties of Novel Poly(aryl ethers Containing β-Naphthalene Pendant Group

    Directory of Open Access Journals (Sweden)

    L. Wang


    Full Text Available Two novel poly(aryl ethers containing β-naphthalene pendant group were synthesized and the structures of these polymers were confirmed by 1HNMR spectroscopy. The polymers exhibited good thermal stabilities with high Tg of 256°C and 274°C, respectively. The polymers are soluble in common organic solvents, such as DMAc, DMSO, CH2Cl2, and CHCl3, and can be electrospun into microfiber (1–5 µm with lots of nanopores (<100 nm from CHCl3 solution. These fibers showed high hydrophobicity, and the contact angle of fibers is above 120°.

  19. Comparison Between the Kutateladze-Khabakhpasheva and Ostwald-De Waele Rheological Models in Describing Generalized Newtonian Liquids with the Use of Experimental Measurements (United States)

    Abaidullin, B. R.; Vachagina, E. K.; Kadyirov, A. I.


    The results of viscosimetric measurements of generalized Newtonian liquids (glycerin, 3% solution of Na-CMC, 70% water solution of starch, TNK Magnum SAE 5W40 motor oil) in the temperature range from 274 to 323 K and shear rates of up to 320 1/s are presented. The method of determining the rheological constants of the Kutateladze-Khabakhpasheva model and of the Ostwald-de Waele model of liquid viscosity power law for generalized Newtonian liquids is presented. The rheological constants of both models are obtained for the indicated liquids.

  20. Leishmanicidal Activity of Novel Synthetic Furoxan and Benzofuroxan Derivatives


    Dutra, Luiz Antônio; Almeida, Letícia; Thais G. Passalacqua; Reis, Juliana Santana; Torres, Fabio A. E.; Martinez, Isabel; Peccinini, Rosangela Gonçalves; Chin, Chung Man; Chegaev, Konstantin; Guglielmo, Stefano; Fruttero, Roberta; Graminha,Marcia A. S.; dos Santos, Jean Leandro


    A novel series of furoxan (1,2,5-oxadiazole 2-oxide) (compounds 3, 4a and -b, 13a and -b, and 14a to -f) and benzofuroxan (benzo[c][1,2,5]oxadiazole 1-oxide) (compounds 7 and 8a to -c) derivatives were synthesized, characterized, and evaluated for in vitro activity against promastigote and intracellular amastigote forms of Leishmania amazonensis. The furoxan derivatives exhibited the ability to generate nitric oxide at different levels (7.8% to 27.4%). The benzofuroxan derivative 8a was able ...

  1. Reviews


    Revista alicantina de estudios ingleses


    Contiene: M. Carmen África Vidal Claramonte. Traducción, manipulación, desconstrucción. Colección Biblioteca Filológica de Salamanca. Salamanca: Ediciones Colegio de España, 1995 / reviewed by Enrique Alcaraz Varó; Diccionario de uso inglés-español/Spanish-English. Directed by Aquilino Sánchez. Madrid: SGEL, 1993, 450 pp. Diccionario de uso pocket inglés-español/Spanish- English. Directed by Aquilino Sánchez. Madrid: SGEL, 1993, 274 pages / reviewed by Miguel Ángel Campos Pardillo...

  2. Bibliografía



    ALBORNOZ (Oswaldo) - Las lachas indígenas en el Ecuador, Guayaquil, 1971. ALCHON, (Suzanne Austin).- Native society and desease in colonial Ecuador, Londres-Nueva York-Melbourne, 1991 BORCHART DE MORENO (Christiana) - "EI período colonial", en Pichincha, monografia histórica de la región nuclear ecuatoriana, Quito, 1981, pp. 195- 274. BORCHART DE MORENO (Christiana).- "Origen y conformación de la hacienda colonial", Nueva Historia del Ecuador, Quito, 1989, vol. 4, pp. 139-166. "Constituciones...

  3. Comparative Study of laryngeal mask airway Supreme and laryngeal mask airway Classic in paralyzed patients



    Aim and Objectives: The present study was undertaken to compare the LMA Classic with LMA Supreme in assessing the ease of insertion, number of attempts, time for insertion, any unwanted responses, stability of device, peak airway pressure, leak volume and leak fraction and postoperative complications.Methods: A total of 274 patients of ASA grade 1 and 2 were included in the study and divided into two groups with 137 patients in each group: the LMA Classic group (group C) and LMA Supreme group...

  4. Violencia doméstica y riesgo de conducta suicida en universitarios adolescentes Domestic violence and risk of suicidal behavior among university students


    Francisco Espinoza-Gómez; Víctor Zepeda-Pamplona; Víctor Bautista-Hernández; Carlos Moisés Hernández-Suárez; Oscar Alberto Newton-Sánchez; Guadalupe R Plasencia-García


    OBJETIVO: Estimar el grado de asociación entre violencia doméstica física, verbal y sexual con la conducta suicida en adolescentes universitarios. MATERIAL Y MÉTODOS: Estudio de casos y controles pareado en estudiantes universitarios de Colima. Los casos fueron 235 adolescentes que presentaron tanto ideación suicida como intento suicida; los controles fueron 470 individuos de la misma edad y sexo. RESULTADOS: El abuso sexual mostró el mayor grado de asociación con conducta suicida (RM= 27.4),...

  5. Meta-Analysis of Early Nonmotor Features and Risk Factors for Parkinson Disease


    Noyce, Alastair J.; Jonathan P Bestwick; Silveira-Moriyama, Laura; Hawkes, Christopher H; Giovannoni, Gavin; Andrew J. Lees; Schrag, Anette


    Objective To evaluate the association between diagnosis of Parkinson disease (PD) and risk factors or early symptoms amenable to population-based screening. Methods A systematic review and meta-analysis of risk factors for PD. Results The strongest associations with later diagnosis of PD were found for having a first-degree or any relative with PD (odds ratio [OR], 3.23; 95% confidence interval [CI], 2.65–3.93 and OR, 4.45; 95% CI, 3.39–5.83) or any relative with tremor (OR, 2.74; 95% CI, 2.1...

  6. AcEST: DK960499 [AcEST

    Lifescience Database Archive (English)

    Full Text Available _RAT Ribosome maturation protein SBDS OS=Rattus norvegicus GN=Sbds PE=2 SV=1 Length ..._MOUSE Ribosome maturation protein SBDS OS=Mus musculus GN=Sbds ..._XENLA Ribosome maturation protein SBDS OS=Xenopus laevis GN=sbds...LIKHIESEN 201 >sp|Q6DIT8|SBDS_XENTR Ribosome maturation protein SBDS OS=Xenopus tropicalis GN=sbds PE=2 SV=1...Ribosome maturation protein SBDS OS=Dictyostelium discoideum GN=sbds PE=3 SV=2 Length = 274 Score = 177 bits

  7. Comparing profitability of Burlina and Holstein Friesian cattle breeds

    Directory of Open Access Journals (Sweden)

    Martino Cassandro


    Full Text Available Aim of this study was to compare profitability of Burlina and Holstein Friesian cows in northern Italy. Cow’s profitability was calculated for each breed, with consideration of economic incentive programs and alternative milk pricing scenarios. The difference in annual profitability between Burlina and Holstein Friesian ranged from −€719 to −€274 per cow per year. In a low-input management level with a cow’s incentive payment and a specific cheese market strategy the low milk yield of Burlina can be compensate respect to Holstein Friesian.

  8. Association of waist circumference with impaired six-minute walk in type 2 diabetes mellitus is independent of cardiac function. (United States)

    Wang, Ying; Yang, Hong; Nolan, Mark; Negishi, Kazuaki; Burgess, John; Marwick, Thomas H


    Subclinical left ventricular dysfunction has been associated with impaired exercise capacity in type 2 diabetes mellitus. In this community-based study of 274 asymptomatic T2DM patients (71±4 years, 55% men) with preserved ejection fraction, a comprehensive resting echocardiogram was performed to gather sensitive systolic and diastolic function parameters (including speckle tracking echocardiography), and a standard six-minute walk test was performed. Tertiles of increasing waist circumference were associated with worsening walk distance. In this community-based study, we found an association of waist circumference with impaired exercise capacity, independent of age, gender, diabetes duration, insulin and angiotensin blockade, LV mass, systolic and diastolic function.

  9. AcEST: BP917599 [AcEST

    Lifescience Database Archive (English)

    Full Text Available S=Desulfotalea psychrophila Align length 31 Score (bit) 32.3 E-value 1.1 Report BLASTX 2.2.19 [Nov-02-2008] ...5 total letters Searching..................................................done Score E Sequences producing ...minopimelate aminotransferase OS=Desulfotalea psychrophila GN=dapL PE=3 SV=2 Length = 408 Score = 32.3 bits ...FGTC 379 >sp|Q8TB68|PRR7_HUMAN Proline-rich protein 7 OS=Homo sapiens GN=PRR7 PE=2 SV=1 Length = 274 Score =...HQHGSQPVRPAHL 131 H HPH H H P HL Sbjct: 112 HAHPHPHHHALPHPPPTHL 130 Score = 23.5

  10. EST Table: FS912717 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available FS912717 E_FL_fufe_27A22_F_0 10/09/28 93 %/271 aa ref|NP_001040215.1| stathmin [Bom...byx mori] gb|ABD36259.1| stathmin [Bombyx mori] 10/09/12 46 %/271 aa FBpp0144714|DgriGH10808-PA 10/08/29 n.h...|Amel|GB18507-PA 10/09/10 52 %/274 aa gi|91083957|ref|XP_975021.1| PREDICTED: similar to stathmin [Tribolium castaneum] FS915193 fufe ...

  11. EST Table: FS919586 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available FS919586 E_FL_fufe_47M17_F_0 10/09/28 93 %/271 aa ref|NP_001040215.1| stathmin [Bom...byx mori] gb|ABD36259.1| stathmin [Bombyx mori] 10/09/13 46 %/271 aa FBpp0144714|DgriGH10808-PA 10/08/29 n.h...|Amel|GB18507-PA 10/09/10 53 %/274 aa gi|91083957|ref|XP_975021.1| PREDICTED: similar to stathmin [Tribolium castaneum] FS915193 fufe ...

  12. Dicty_cDB: Contig-U09216-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available 46 0.024 5 ( AF396517 ) Paraclisis hyalina isolate PARhyal2 12S ribosomal... 40 ...0.026 2 ( DY887737 ) CeleSEQ4360 Cunninghamella elegans pBluescript (E... 52 0.028 1 ( AF396516 ) Paraclisis...otus purpuratus clone R3-4017N15, W... 44 0.45 6 ( AY160069 ) Paraclisis hyalina ...Fosmid clone:GBMFno274_d... 38 5.6 2 ( AY160070 ) Paraclisis hyalina isolate GLA901 12S ribosomal R... 40 6.

  13. Application of powder metallurgy to an advanced-temperature nickel-base alloy, NASA-TRW 6-A (United States)

    Freche, J. C.; Ashbrook, R. L.; Waters, W. J.


    Bar stock of the NASA-TRW 6-A alloy was made by prealloyed powder techniques and its properties evaluated over a range of temperatures. Room temperature ultimate tensile strength was 1894 MN/sq m (274 500 psi). The as-extruded powder product showed substantial improvements in strength over the cast alloy up to 649 C (1200 F) and superplasticity at 1093 C (2000 F). Both conventional and autoclave heat treatments were applied to the extruded powder product. The conventional heat treatment was effective in increasing rupture life at 649 and 704 C (1200 and 1300 F); the autoclave heat treatment, at 760 and 816 C (1400 and 1500 F).

  14. JPRS Report - Science & Technology Japan: New Functional Materials. (United States)


    Tokyo, 7-3-1 Hongo , Bunkyo-ku, Tokyo 113, Japan 1. Introduction We have succeeded in constructing high-spin polycarbenes m-PhC(C6H4C)n_lPh (n=4,5,6...Funabashi, Chiba 274, Japan tDepartment of Chemistry, Faculty of Science, The University of Tokyo, Hongo , Bunkyo-ku, Tokyo 113, Japan 1...Chemistry Faculty of Engineering The University of Tokyo 7-3-1, Hongo , Bunkyo-ku, Tokyo, Japan 1. Introduction It is well known that on

  15. AcEST: BP912320 [AcEST

    Lifescience Database Archive (English)

    Full Text Available Golgin subfamily A member 4 OS=Mus musculus GN=Golga4 PE=1 SV=2 Length = 2238 Sco...ANPO Putative uncharacterized protein OS=Vande... 50 9e-05 tr|Q5U4E6|Q5U4E6_RAT Golga4 protein (Fragment) OS...: 90 QNASQKRYMEEIGFLQSE 37 + + G L+SE Sbjct: 257 VQRDKSELEKNFGSLESE 274 >tr|Q5U4E6|Q5U4E6_RAT Golga4 protein... (Fragment) OS=Rattus norvegicus GN=Golga4 PE=2 SV=1 Length = 591 Score = 49.3 bi


    Directory of Open Access Journals (Sweden)

    Aurean de Paula Carvalho


    Full Text Available This study used the Water Quality Index (IQA and aimed to evaluate the water quality of the Reservoir of Soledade, in Soledade, the state of Paraiba. The study was conducted in the years 2008 and 2009, when they were assessed the physical, chemical and biological parameters. The results showed that the waters of the Reservoir of Soledade can be classified as being acceptable CETESB, although some parameters when compared with environmental laws aren’t in accordance with the determined standards of quality set by CONAMA Resolution 274/2000 and 357/05 to brackish water class one, two fresh and salty.

  17. Dicty_cDB: Contig-U14088-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available 0 Length of query: 109 Length of database: 95,242,211,685 Length adjustment: 22 Effective... length of query: 87 Effective length of database: 93,199,600,587 Effective search space: 8108365251069 of HSP's successfully gapped: 0 Length of query: 36 Length of database: 1,051,180,864 Length adjustment: 10 Effective... length of query: 26 Effective length of database: 1,018,815,274 Effective... search space: 26489197124 Effective search space used: 26489197124 Neighboring words threshold: 12 Win

  18. Dicty_cDB: Contig-U14613-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available 95,242,211,685 Length adjustment: 22 Effective length of query: 88 Effective length of database: 93,199,600,587 Effective... search space: 8201564851656 Effective search space used: 8201564851656 X1: 11 (21.8 bits) S2:...ber of HSP's successfully gapped: 0 Length of query: 36 Length of database: 1,051,180,864 Length adjustment: 10 Effective... length of query: 26 Effective length of database: 1,018,815,274 Effective... search space: 26489197124 Effective search space used: 26489197124 Neighboring words threshold: 12 Wi

  19. Dicty_cDB: Contig-U13173-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available ective length of query: 86 Effective length of database: 93,199,600,587 Effective... search space: 8015165650482 Effective search space used: 8015165650482 X1: 11 (21.... Length of database: 1,051,180,864 Length adjustment: 10 Effective length of query: 26 Effective length of d...atabase: 1,018,815,274 Effective search space: 26489197124 Effective search space...ts to DB: 0 Number of sequences better than 10.0: 0 Length of query: 108 Length of database: 95,242,211,685 Length adjustment: 22 Eff

  20. 金属材料分析方法的选择和施行 第四讲 金属材料中钛的测定(续)%Choice and Practice of Analytical Methods in Metal Analysis Lecture 4 Determination of Titanium in Metals and Alloys (Continued)

    Institute of Scientific and Technical Information of China (English)



    @@ 2.7.4钢铁及纯铝中痕量钛的测定 在2.7.1至2.7.3节中所引述的各方法的测定下限均为w(Ti)0.01%.不适用于含钛量低于此限的试样的分析.但在实际工作中却有要求测定钢铁、纯铝等金属材料中的痕量钛.为此选择以下两方法供参考.

  1. Dicty_cDB: Contig-U13199-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available GP158104 Atlantic salmon Swimbladder cDNA librar... 50 0.001 2 ( DE224535 ) Trifo...:RCG19263. 50 0.001 2 ( CK895836 ) SGP158365 Atlantic salmon Swimbladder cDNA lib...SGP158591 Atlantic salmon Swimbladder cDNA librar... 50 0.001 2 ( DV106194 ) SGP280779 Atlantic salmon Liver...CK897076 ) SGP159636 Atlantic salmon Swimbladder cDNA librar... 50 0.001 2 ( CN242942 ) EST008814 Mycelium a... sequence from clone RP24-274P18 on chro... 42 0.002 4 ( CK896320 ) SGP158862 Atlantic salmon Swimbladder cD

  2. Selenium-enriched Agaricus bisporus mushroom protects against increase in gut permeability ex vivo and up-regulates glutathione peroxidase 1 and 2 in hyperthermally-induced oxidative stress in rats. (United States)

    Maseko, Tebo; Dunshea, Frank Rowland; Howell, Kate; Cho, Hyun-Jung; Rivera, Leni Rose; Furness, John Barton; Ng, Ken


    Dietary effects of organic Se supplementation in the form of Se-enriched Agaricus bisporus mushroom on ileal mucosal permeability and antioxidant selenoenzymes status in heat induced oxidative stress in rats were evaluated. Acute heat stress (40 °C, 21% relative humidity, 90 min exposure) increased ileum baseline short circuit current (Isc; 2.40-fold) and epithelial conductance (Ge; 2.74-fold). Dietary supplementation with Se-enriched A. bisporus (1 µg Se/g feed) reduced (p bisporus protected against increase in ileum permeability and up-regulated GPx-1 and GPx-2 expression, selenoenzymes relevant to mitigating oxidative stress.

  3. Summary of the U.S. specimen matrix for the HFIR 13J varying temperature irradiation capsule

    Energy Technology Data Exchange (ETDEWEB)

    Zinkle, S.J. [Oak Ridge National Lab., TN (United States)


    The US specimen matrix for the collaborative DOE/Monbusho HFIR 13J varying temperature irradiation capsule contains two ceramics and 29 different metals, including vanadium alloys, ferritic/martensitic steels, pure iron, austenitic stainless steels, nickel alloys, and copper alloys. This experiment is designed to provide fundamental information on the effects of brief low-temperature excursions on the tensile properties and microstructural evolution of a wide range of materials irradiated at nominal temperatures of 350 and 500 C to a dose of {approximately}5 dpa. A total of 340 miniature sheet tensile specimens and 274 TEM disks are included in the US-supplied matrix for the irradiation capsule.

  4. Percepción de comportamientos de cuidado humanizado de enfermería en la clínica del country



    El objetivo del estudio es describir la percepción de los comportamientos de cuidado humanizado brindados por el personal de enfermería a la persona hospitalizada y a sus cuidadores familiares en la Clínica del Country. Este es un estudio descriptivo exploratorio con abordaje cuantitativo, realizado entre los meses de junio a octubre de 2005.Con una muestra de 274 personas hospitalizadas, se evaluó la percepción de cuidado humanizado de enfermería, mediante el empleo del instrumento “P...

  5. Catalytic Synthesis of Substrate-Free, Aligned and Tailored High Aspect Ratio Multiwall Carbon Nanotubes in an Ultrasonic Atomization Head CVD Reactor


    Fahad Ali Rabbani; Zuhair Omar Malaibari; Muataz Ali Atieh; Ammar Jamie


    Chemical vapor deposition (CVD) method has proven its benchmark, over other methods, for the production of different types of carbon nanotubes (CNT) on commercial and lab scale. In this study, an injection vertical CVD reactor fitted with an ultrasonic atomization head was used in a pilot-plant scale (height 274 cm, radius 25 cm) for semicontinuous production of multiwall carbon nanotubes (MWCNTs). p-Xylene was used as a hydrocarbon precursor in which ferrocene was dissolved and provided the ...

  6. Status of larynx in children with congenital cleft of upper lip and palate

    Directory of Open Access Journals (Sweden)

    Nigora Makhkamova


    Full Text Available Study of 215 children with congenital cleft of upper lip and palate in the age of 1.5 to 15 years has established the organic dysphonia in 27.4% of patients. Of the organic diseases of larynx there were edema, hypertrophy, nodules of vocal folds and chronic laryngitis whose frequency is directly dependent on duration and severity of the defect, age of patient and the timing of recovery of velopharyngeal ring. Pathology of the larynx gradually disappears with the growth of the patient after plastic reconstruction of oronasal defect.

  7. AcEST: BP914326 [AcEST

    Lifescience Database Archive (English)

    Full Text Available YMU001_000057_F07 599 Adiantum capillus-veneris mRNA. clone: YMU001_000057_F07. BP91432...6 CL274Contig1 Show BP914326 Clone id YMU001_000057_F07 Library YMU01 Length 599 Definition Adiantum cap...illus-veneris mRNA. clone: YMU001_000057_F07. Accession BP914326 Tissue type prothallium Developmental stage...LAST: a new generation of protein database search programs, Nucleic Acids Res. 25:3389-3402. Query= BP914326...AST: a new generation of protein database search programs, Nucleic Acids Res. 25:3389-3402. Query= BP91432

  8. Rational Taxation

    Institute of Scientific and Technical Information of China (English)


    Individual income tax reform is expected to narrow the gap between the rich and the poor People earning less than 2,000 yuan ($274)a month will not have to pay income tax in 2008.This is good news for Chinese breadwinners who have increasingly felt the pin- ch of rising prices in the past year. On December,23 2007,the draft amend- ment to the Law on Individual Income Tax was submitted to the Standing Committee of the National People’s Congress(NPC),

  9. The bolometric focal plane array of the Polarbear CMB experiment

    CERN Document Server

    Arnold, K; Anthony, A E; Barron, D; Boettger, D; Borrill, J; Chapman, S; Chinone, Y; Dobbs, M A; Errard, J; Fabbian, G; Flanigan, D; Fuller, G; Ghribi, A; Grainger, W; Halverson, N; Hasegawa, M; Hattori, K; Hazumi, M; Holzapfel, W L; Howard, J; Hyland, P; Jaffe, A; Keating, B; Kermish, Z; Kisner, T; Jeune, M Le; Lee, A T; Linder, E; Lungu, M; Matsuda, F; Matsumura, T; Miller, N J; Meng, X; Morii, H; Moyerman, S; Myers, M J; Nishino, H; Paar, H; Quealy, E; Reichardt, C; Richards, P L; Ross, C; Shimizu, A; Shimmin, C; Shimon, M; Sholl, M; Siritanasak, P; Spieler, H; Stebor, N; Steinbach, B; Stompor, R; Suzuki, A; Tomaru, T; Tucker, C; Zahn, O


    The Polarbear Cosmic Microwave Background (CMB) polarization experiment is currently observing from the Atacama Desert in Northern Chile. It will characterize the expected B-mode polarization due to gravitational lensing of the CMB, and search for the possible B-mode signature of inflationary gravitational waves. Its 250 mK focal plane detector array consists of 1,274 polarization-sensitive antenna-coupled bolometers, each with an associated lithographed band-defining filter. Each detector's planar antenna structure is coupled to the telescope's optical system through a contacting dielectric lenslet, an architecture unique in current CMB experiments. We present the initial characterization of this focal plane.

  10. Rawhide Energy Station, Fort Collins, Colorado

    Energy Technology Data Exchange (ETDEWEB)

    Peltier, R.


    The staff of Platte River Power Authority's Rawhide Energy Station have been racking up operating stats and an environmental performance record that is the envy of other plant managers. In the past decade Rawhide has enjoyed an equivalent availability factor in the mid to high 90s and an average capacity factor approaching 90%. Still not content with this performance, Rawhide invested in new technology and equipment upgrades to further optimise performance, reduce emissions, and keep cost competitive. The Energy Station includes four GE France 7EA natural gas-fired turbines totalling 260 MW and a 274 MW coal-fired unit located in northeastern Colorado. 7 figs.

  11. New strategy for diagnosis and treatment of gynecological cancer

    Institute of Scientific and Technical Information of China (English)

    LANG Jing-he


    @@ In the 21st century medicine is characterized by population problem, the great impact of computer and information technology, the contribution of genetics development to disease prevention and treatment, and the reform of health care system. By 2025, there will be 274 million people over 60 years old and cancer may be the primary killer as well in China. The incidences of cancers of the lung, intestine, and breast are on the rise; the incidence of cervical cancer is decreasing in developed countries while increasing in developing ones.

  12. [Vertical dimension in the OSAHS in adults: an example of functional alteration]. (United States)

    Raskin, S; Limme, M


    Obstructive sleep apnea and hypoapnea syndrome (OSAHS) is important to orthodontists for several reasons. The authors, after defining OSAHS and describing it briefly, review the literature dealing with the cranio-facial morphology of apnea patients. They report the results of their cephalometric study, which is based on an architectural analysis of 274 patients. Their facial characteristics, especially vertical dimension, are consistent with those displayed by mouth breathing children. Changes in respiratory functioning modify the mechanical behavior and the structures of the upper airways. Osseous tissues also show signs caused by these changes. The authors propose an etiopathogenic model.

  13. Microbiologically Influenced Corrosion (United States)


    temporarily protective films of iron sulfides form on low-alloy steel surfaces with a conse- quent reduction in the corrosion rate. High rates of SPP...fine clay sun·ounded by a film of water. Under low flow conditions, these particles precipitate and form a sludge deposit. 27.4 TESTING 27 .4.1 A...tion of iron sulfide within a 28-day period were scored as positive for SRB. Additionally, the time required for black. ening was suggested as a

  14. A NASTRAN Vibration Model of the AH-1G Helicopter Airframe. Volume 1 (United States)


    9303 ... 456 AAA . . 123 DCC 9307 456 AAA - - 123 DCC 1 9313 456 AAA - - 123 DCC 9317 456 AAA - 13 OC 9331 456 AAA - - 123 DC 9333 456 AAA...DCC 9313 456 AAA - - 123 DCC 11503 3456 AAAA - - 12 DC 13801 456 AAA - 123 DCC 13803 456 AAA - - 123 DCC 13821 456 AAA - - 123 DCC , 14801...TO300— -«^*6 -11. .4M 8 0.0 -3. 276 -13, .452 9 0.0 5. 174 -13. ,472 10 n _ ft o en 13,274 -11. ,622 11 0.0 19. 194 -3. ,?62 SECTICN PPQofRTlES A^ EA

  15. Bombing the European Axis Powers. A Historical Digest of the Combined Bomber Offensive 1939-1945 (United States)


    warships Scharnhorst, Gneisenau, and Prinz Eugen leave Brest and pass through the Strait of Dover to Germany. Bomber Command’s first use of Boston...unrestricted strafing on French railroads begins (such missions soon dubbed “Chat- tanooga Choo Choos ,” after hit song of period). 27 May: Eighth Air Force—three...Cassino, 274, 277–78, 298, 311, 316, 457 chaff, 133, 156 Chamberlain, Neville, 4, 7, 9 Channel Islands, 81, 137, 448 “Chattanooga Choo Choos ,” 342

  16. Choroidal Freckling in Pediatric Patients Affected by Neurofibromatosis Type 1. (United States)

    Vagge, Aldo; Nelson, Leonard B; Capris, Paolo; Traverso, Carlo Enrico


    Greater understanding of choroidal freckling in patients affected by neurofibromatosis type 1 (NF1) has changed the previous belief that choroidal lesions are unusual in eyes with this disease. In fact, the high frequency of freckling suggests that the choroid is a structure commonly affected in patients with NF1. A review of patients aged 16 years or younger was performed. Recent studies using near-infrared reflectance imaging have shown that choroidal freckling frequently occurred in pediatric patients. As a result of these findings, some authors have suggested that choroidal freckling should be considered as a new diagnostic criterion for NF1. [J Pediatr Ophthalmol Strabismus. 2016;53(5):271-274.].

  17. Long-Term Prospective Study of 6104 Survivors of Arsenic Poisoning During Infancy Due to Contaminated Milk Powder in 1955


    Tanaka, Hideo; Tsukuma, Hideaki; Oshima, Akira


    Background In 1955, an outbreak of arsenic poisoning caused by ingestion of arsenic-contaminated dry milk occurred in western Japan. We assessed the excess mortality among Japanese who were poisoned during this episode as infants. Methods We identified and enrolled 6104 survivors (mean age at enrollment, 27.4 years) who had ingested contaminated milk when they were age 2 years or younger; they were followed until 2006 (mean duration of follow-up, 24.3 years). Death certificates of subjects wh...

  18. Total Solar Eclipse of 17-18 March 1988, (United States)


    05.0 Sapporo , Japan 2 35 29.9 55.5 0.637 46 177 .127 00.0 +37 30.0 Seoul, S. Korea 2 07 03.0 38.2 0.487 46 145 .121 25.6 .31 11.4 Shanghai Obs., P.8...18.2 78.2 0.820 37 87 .106 52.0 +47 54.0 Ulaanbaatac. Mongolia 1 58 04.1 5.3 0.126 27 127 * 79 27.4 +29 21.6 Uttar Pradesh State Obs.. India 1 03 46.6

  19. Does the Country-of-Origin (COO) of food products influence consumer evaluations?

    DEFF Research Database (Denmark)

    Krystallis, Athanasios; Chryssohoidis, G.


    The present study attempts to assess the impact of the COO effect on the evaluation of specific food products by Greek consumers. This issue has been examined exhaustively in the international literature albeit there are very few studies concerning food products. A particular effort is geared...... and confirmatory factor analyses. Data were collected though personal interviews with a sample of 274 respondents, which compared two food products of Greek origin (ham and yellow cheese) to their counterparts from Italy and the Netherlands. Results indicate that respondents exhibit a marginally ethnocentric...

  20. Search for the Standard Model Higgs Boson Produced in Association with Top Quarks

    Energy Technology Data Exchange (ETDEWEB)

    Wilson, Jonathan Samuel [Ohio State U.


    We have performed a search for the Standard Model Higgs boson produced in association with top quarks in the lepton plus jets channel. We impose no constraints on the decay of the Higgs boson. We employ ensembles of neural networks to discriminate events containing a Higgs boson from the dominant tt¯background, and set upper bounds on the Higgs production cross section. At a Higgs boson mass mH = 120 GeV/c2 , we expect to exclude a cross section 12.7 times the Standard Model prediction, and we observe an exclusion 27.4 times the Standard Model prediction with 95 % confidence.

  1. Results of the SDCS (Special Data Collection System) Attenuation Experiment (United States)


    for radiation patterns were made in these figures. Instrument gains are shown on each trace. 91 I -91- 4 SANTIAGO DEL ERSTERO, ARGENTINA 27.4*S 63.3*W...quantities. JI -93- SANTIAGO DEL ESTERO. ARGENTINA ARGENTINA WESTERN BRAZIL 08 DEC 62 21:27:18.0 29 SEP 62 15:17:47.7 28 NOV 64 15:41:33.4 2.7°S, 63.0W ob=7.0...the average Q ScS values for the whole mantle of 600 by Kovach and Anderson (1964) and 580 by Sato and Espinosa (1967) may be indicative of Q values in

  2. Macromycetes of oak-lime-hornbeam woods in the Niepołomice Forest near Kraków (S Poland - monitoring studies

    Directory of Open Access Journals (Sweden)

    Władysława Wojewoda


    Full Text Available In the years 1994-1996 studies on macromycetes of the Niepołomice Forest near Kraków were made in four plots designated in deciduous forests (Tilio-Carpinetum stachyetosum with a population of Carpinus betulus, Quercus robur and Tilia cordata (the size of each plot was 1000 m2. The observations were made through an international project "Mycological monitoring in European oak forests". As many as 274 species were recorded, including 234 saprobic, 33 mycorrhizal, and 7 parasitic fungi. Moreover, 15 species of fungi are connected with oak, 24 species of fungi are threatened, and 16 species are new to Poland.

  3. Medical Surveillance Monthly Report. Volume 18, Number 2, February 2011 (United States)


    2,420 3,113 73 274 347 620 2,146 2,766 Genitourinary system (580 - 629, except breast disorders...1,046 30 140 170 204 672 876 Infectious and parasitic diseases (001 - 139) 145 710 855 23 63 86...ill-defined conditions Genitourinary system Breast disorders 0.0 5.0 10.0 15.0 20.0 25.0 30.0 2003 2004 2005 2006 2007 2008 2009 2010 % o f t ot al

  4. Documentation of the Tonge-Ramesh Material Model for Release 2015-06-05-152756 (United States)


    Coefficient of friction for clean self contact. Used in the micromechanics calculation. 3 28) FlawAngle: Radians—Angle between the maximum compressive...based on a wing-cracking mechanism (Tonge 2014, eqs. 4.57 and 4.58). It depends on the crack-face coefficient of friction (FlawFriction), applied load...current state of the material (Simo and Hughes 2000, sec . 2.7.4). The plastic flow direction ism = (n+ ζAÎ)/ √ 1 + ζ2A2. Here n = τ dev/||τ dev||, Î

  5. Using Exenatide Twice Daily or Insulin in Clinical Practice

    DEFF Research Database (Denmark)

    Mathieu, Chantal; Ostenson, Claes-Göran; Matthaei, Stephan;


    were recruited; 1,114 patients in the exenatide BID cohort and 1,274 patients in the insulin cohort were eligible for the 24-month analysis. During the study, 42.2% and 36.0% of patients from each cohort, respectively, had a significant treatment change. By 24 months, improved mean glycated hemoglobin...... BID cohort and 36.8% of the insulin cohort; 25.9% of the exenatide BID cohort and 10.0% of the insulin cohort had met the secondary endpoint of glycated hemoglobin

  6. Dicty_cDB: SHA551 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available HSP's gapped (non-prelim): 0 length of query: 131 length of database: 80,480,566 effective HSP length: 17 effective... length of query: 114 effective length of database: 78,821,179 effective search space: 8985614406 effective...ssful extensions: 0 Number of sequences better than 10.0: 0 length of query: 131 length of database: 55,409,929,374 effective... HSP length: 22 effective length of query: 109 effective length of database: 54,274,350,600 effective... search space: 5915904215400 effective search space used: 5915904215400 T: 0 A: 0 X1: 11 (21.8 bit

  7. Dicty_cDB: SHI556 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available ength of query: 206 length of database: 80,480,566 effective HSP length: 17 effective... length of query: 189 effective length of database: 78,821,179 effective search space: 14897202831 effective...0 Number of sequences better than 10.0: 0 length of query: 206 length of database: 61,528,524,606 effective HSP length: 22 effective... length of query: 184 effective length of database: 60,274,665,802 effective... search space: 11090538507568 effective search space used: 11090538507568 T: 0 A: 0 X1: 1

  8. Association of the solute carrier family 11 member 1 gene polymorphisms with susceptibility to leprosy in a Brazilian sample

    Directory of Open Access Journals (Sweden)

    Maria José Franco Brochado


    Full Text Available Natural resistance-associated macrophage protein 1/solute carrier family 11 member 1 gene (Nramp1/Slc11a1 is a gene that controls the susceptibility of inbred mice to intracellular pathogens. Polymorphisms in the human Slc11a1/Nramp1 gene have been associated with host susceptibility to leprosy. This study has evaluated nine polymorphisms of the Slc11a1/Nramp1 gene [(GTn, 274C/T, 469+14G/C, 577-18G/A, 823C/T, 1029 C/T, 1465-85G/A, 1703G/A, and 1729+55del4] in 86 leprosy patients (67 and 19 patients had the multibacillary and the paucibacillary clinical forms of the disease, respectively, and 239 healthy controls matched by age, gender, and ethnicity. The frequency of allele 2 of the (GTn polymorphism was higher in leprosy patients [p = 0.04, odds ratio (OR = 1.49], whereas the frequency of allele 3 was higher in the control group (p = 0.03; OR = 0.66. Patients carrying the 274T allele (p = 0.04; OR = 1.49 and TT homozygosis (p = 0.02; OR = 2.46, such as the 469+14C allele (p = 0.03; OR = 1.53 of the 274C/T and 469+14G/C polymorphisms, respectively, were more frequent in the leprosy group. The leprosy and control groups had similar frequency of the 577-18G/A, 823C/T, 1029C/T, 1465-85G/A, 1703G/A, and 1729+55del4 polymorphisms. The 274C/T polymorphism in exon 3 and the 469+14G/C polymorphism in intron 4 were associated with susceptibility to leprosy, while the allele 2 and 3 of the (GTn polymorphism in the promoter region were associated with susceptibility and protection to leprosy, respectively.

  9. Association of the solute carrier family 11 member 1 gene polymorphisms with susceptibility to leprosy in a Brazilian sample. (United States)

    Brochado, Maria José Franco; Gatti, Maria Fernanda Chociay; Zago, Marco Antônio; Roselino, Ana Maria


    Natural resistance-associated macrophage protein 1/solute carrier family 11 member 1 gene (Nramp1/Slc11a1) is a gene that controls the susceptibility of inbred mice to intracellular pathogens. Polymorphisms in the human Slc11a1/Nramp1 gene have been associated with host susceptibility to leprosy. This study has evaluated nine polymorphisms of the Slc11a1/Nramp1 gene [(GT)n, 274C/T, 469+14G/C, 577-18G/A, 823C/T, 1029 C/T, 1465-85G/A, 1703G/A, and 1729+55del4] in 86 leprosy patients (67 and 19 patients had the multibacillary and the paucibacillary clinical forms of the disease, respectively), and 239 healthy controls matched by age, gender, and ethnicity. The frequency of allele 2 of the (GT)n polymorphism was higher in leprosy patients [p = 0.04, odds ratio (OR) = 1.49], whereas the frequency of allele 3 was higher in the control group (p = 0.03; OR = 0.66). Patients carrying the 274T allele (p = 0.04; OR = 1.49) and TT homozygosis (p = 0.02; OR = 2.46), such as the 469+14C allele (p = 0.03; OR = 1.53) of the 274C/T and 469+14G/C polymorphisms, respectively, were more frequent in the leprosy group. The leprosy and control groups had similar frequency of the 577-18G/A, 823C/T, 1029C/T, 1465-85G/A, 1703G/A, and 1729+55del4 polymorphisms. The 274C/T polymorphism in exon 3 and the 469+14G/C polymorphism in intron 4 were associated with susceptibility to leprosy, while the allele 2 and 3 of the (GT)n polymorphism in the promoter region were associated with susceptibility and protection to leprosy, respectively.

  10. Rock blasting and explosives engineering

    Energy Technology Data Exchange (ETDEWEB)

    Persson, P.-A.; Holmberg, R.; Lee, J. (New Mexico Institute of Mining and Technology, Socorro, NM (United States). Research Center for Energetic Materials)


    The book covers the practical engineering aspects of different kinds of rock blasting. It includes a thorough analysis of the cost of the entire process of tunneling by drilling and blasting compared with full-face boring. It covers the economics of the entire rock blasting operation and its dependence on the size of excavation. The book highlights the fundamentals of rock mechanics, shock waves and detonation, initiation and mechanics of rock motion. It describes the engineering design principles and computational techniques for many separate mining methods and rock blasting operations. 274 refs.

  11. Cu-Al-O Nanofi bers Fabricated by Electrospinning and Their Ozone Sensing Properties at Room Temperature

    Institute of Scientific and Technical Information of China (English)

    L Mo; CAO Jiajia; WANG Yu; SHEN Hongzhi; WANG Yiding


    Cu-Al-O nanofibers are synthesized by an electrospinning method. After electrospinning process, these nanofi bers were thermally treated at different temperatures from 900 to 1 100ć. The morphology and crystal structure of thefi bers were analyzed by scanning electron microscopy and X-ray diffraction. Thick fi lm gas sensors were fabricated by spinning the nanofi bers on a ceramic substrate with Au-Pt interdigitated electrodes. These sensors exhibited high ozone sensing properties at room temperature. When the sensors were exposed to 100 ppm ozone, the response time was about 2.74 s, and the recovery was about 12.68 s.

  12. Long-term effect of early-life stress from earthquake exposure on working memory in adulthood


    Li, Na; Wang, Yumei; Zhao, Xiaochuan; Gao, Yuanyuan; Song, Mei; Yu, Lulu; Wang, Lan; Li, Ning; Chen, Qianqian; Li, Yunpeng; Cai,Jiajia; Wang, Xueyi


    Objective The present study aimed to investigate the long-term effect of 1976 Tangshan earthquake exposure in early life on performance of working memory in adulthood. Methods A total of 907 study subjects born and raised in Tangshan were enrolled in this study. They were divided into three groups according to the dates of birth: infant exposure (3–12 months, n=274), prenatal exposure (n=269), and no exposure (born at least 1 year after the earthquake, n=364). The prenatal group was further d...

  13. Functions of key residues in the ligand-binding pocket of vitamin D receptor: Fragment molecular orbital interfragment interaction energy analysis (United States)

    Yamagishi, Kenji; Yamamoto, Keiko; Yamada, Sachiko; Tokiwa, Hiroaki


    Fragment molecular orbital-interfragment interaction energy calculations of the vitamin D receptor (VDR)/1α,25-dihydroxyvitamin D 3 complex were utilized to assign functions of key residues of the VDR. Only one residue forms a significant interaction with the corresponding hydroxy group of the ligand, although two residues are located around each hydroxy group. The degradation of binding affinity for derivatives upon removal of a hydroxy group is closely related to the trend in the strength of the hydrogen bonds. Type II hereditary rickets due to an Arg274 point mutation is caused by the lack of the strongest hydrogen bond.

  14. Tungsten Export Price Raised Due to Customs Tax Regulations

    Institute of Scientific and Technical Information of China (English)


    <正>Affected by the export tax rise, China’s tungsten export price rose by about 40 per cent in the first 10 months of 2006. The average price of Ammonium Paratungstate (APT) was US$23,000/MT, up by 43.5 per cent year-on-year, and that of ferro-tungsten, blue tungsten oxide as well as yellow oxide also increased by 32.4 per cent to US$24,000/MT, 27.4 per cent to US$25,000/MT and 42.6 per cent to US$26,000/MT respectively.

  15. Japan’s Decision for War in 1941: Some Enduring Lessons (United States)


    probably mean war. As early as October 1940 Roosevelt told Hull and Under-Secretary of State Sumner Welles that an oil shut-off would force Japan to... Lewis believes this best explains the Japanese determination to wage a “hopeless” resistance in the Central Pacific from 1943 to 1945: While the...War, p. 274. 75. Adrian R. Lewis , The American Culture of War: The History of U.S. Military Force from World War II to Operation Iraqi Freedom, New

  16. Prevalencia del síndrome metabólico en una población de niños obesos en el País Vasco, su relación con la resistencia a la insulina, las adipoquinas y grhelina


    Aguayo Calcena, Aníbal


    274 p. : graf. Introducción: El síndrome metabólico es un conjunto de alteraciones antropométricas, clínicas y bioquímicas que predisponen al desarrollo de la enfermedad cardiovascular arterioesclerótica y a la diabetes mellitus tipo 2 a lo largo de la vida. En la asociación entre la obesidad y el síndrome metabólico, la resistencia a la insulina es clave porque constituye el sustrato fisiopatológico sobre el cual se desarrolla el síndrome. Igualmente las adipoquinas y citoquinas pueden i...

  17. Regulation of serum potassium during insulin-induced hypoglycemia. (United States)

    Petersen, K G; Schlüter, K J; Kerp, L


    Counterregulatory secretion of epinephrine occurs during severe insulin-induced hypoglycemia. Under these conditions (minimal plasma glucose 27.4 +/- 1 mg/dl) the decrease of serum potassium concentration (0.9 mVal/L) is mediated by two mechanisms: insulin-induced (0.48 mVal/L) and epinephrine-induced (0.42 mVal/L) cellular uptake of potassium. Epinephrine-induced serum potassium uptake appears to be more sensitive to beta-adrenoceptor blockade than glucose production. The intensification of insulin-induced hypokalemia by epinephrine is of clinical significance.

  18. The Use and Effect of Social Capital in New Venture Creation - Solo Entrepreneurs vs. New Venture Teams


    Cantner, Uwe; Stützer, Michael


    This paper examines the use of social capital in the venture creation process. We compare solo entrepreneurs (n=182) and new venture teams (n=274) from a random sample of start-ups in innovative industries and test social capital use and its effects on firm performance. Our results reveal that solo entrepreneurs and new venture teams do not differ in their degree of use of social capital. However, there are differences in the determinants of social capital use in both groups. We find that wea...

  19. EST Table: FS931756 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available FS931756 E_FL_fwgP_32C23_F_0 10/09/28 73 %/261 aa ref|NP_001136223.1| osiris 7 [Bom...byx mori] gb|ACJ12371.1| osiris7 [Bombyx mori] 10/09/13 40 %/277 aa FBpp0255200|DyakGE10190-PA 10/08/29 n.h ...mel|GB13419-PA 10/09/10 38 %/274 aa gi|91091224|ref|XP_967197.1| PREDICTED: similar to osiris 7 [Tribolium castaneum] FS931205 fwgP ...

  20. EST Table: FS935773 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available FS935773 E_FL_fwgP_44A15_F_0 10/09/28 73 %/261 aa ref|NP_001136223.1| osiris 7 [Bom...byx mori] gb|ACJ12371.1| osiris7 [Bombyx mori] 10/09/13 40 %/277 aa FBpp0255200|DyakGE10190-PA 10/08/29 n.h ...mel|GB13419-PA 10/09/10 38 %/274 aa gi|91091224|ref|XP_967197.1| PREDICTED: similar to osiris 7 [Tribolium castaneum] FS931205 fwgP ...

  1. EST Table: FS933711 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available FS933711 E_FL_fwgP_37O05_F_0 10/09/28 73 %/261 aa ref|NP_001136223.1| osiris 7 [Bom...byx mori] gb|ACJ12371.1| osiris7 [Bombyx mori] 10/09/13 40 %/277 aa FBpp0255200|DyakGE10190-PA 10/08/29 n.h ...mel|GB13419-PA 10/09/10 38 %/274 aa gi|91091224|ref|XP_967197.1| PREDICTED: similar to osiris 7 [Tribolium castaneum] FS931205 fwgP ...

  2. EST Table: FS938425 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available FS938425 E_FL_fwgP_51P07_F_0 10/09/28 73 %/259 aa ref|NP_001136223.1| osiris 7 [Bom...byx mori] gb|ACJ12371.1| osiris7 [Bombyx mori] 10/09/13 39 %/276 aa FBpp0255200|DyakGE10190-PA 10/08/29 n.h ...mel|GB13419-PA 10/09/10 38 %/274 aa gi|91091224|ref|XP_967197.1| PREDICTED: similar to osiris 7 [Tribolium castaneum] FS931205 fwgP ...

  3. EST Table: FS922446 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available FS922446 E_FL_fwgP_04K13_F_0 10/09/28 73 %/261 aa ref|NP_001136223.1| osiris 7 [Bom...byx mori] gb|ACJ12371.1| osiris7 [Bombyx mori] 10/09/13 40 %/277 aa FBpp0255200|DyakGE10190-PA 10/08/29 n.h ...mel|GB13419-PA 10/09/10 38 %/274 aa gi|91091224|ref|XP_967197.1| PREDICTED: similar to osiris 7 [Tribolium castaneum] FS931205 fwgP ...

  4. Quantitative determination of nabumetone in the nebumetone capsules by spectrophotofluorimetry%荧光分光光度法测定萘丁美酮胶囊的含量

    Institute of Scientific and Technical Information of China (English)

    李玉兰; 黄俊杰


    目的:建立萘丁美酮胶囊的荧光测定法。方法:以无水乙醇为溶剂,采用荧光分光光度法测定萘丁美酮胶囊的含量,测定波长为Ex=274.0nm,Em=355.0nm。结果:平均回收率99.91%,RSD为0.75%,线性范围为0.01~2μg/ml。结论:该方法简便、灵敏、准确,适用于萘丁美酮胶囊的含量测定。%OBJECTIVE:To establish a method for the determination of nabumetone capsule by fluoresscent spectrophotmetry.METHOD:Spectrophotofluorimetry was used to determine the content of nabumetone capsules at the fixed wavelength,Ex=274.0nm,Em=355.0nm,in anhydrous ethanol.RESULTS:The average recovery is 99.91%,RSD=0.75%.The liner range is between 0.01~2μg/ml.CONCLUSION:The method is simple,sensitive and accuracy.

  5. A food basket investigation during the autumn of 1994; Matkorgsundersoekning hoesten 1994

    Energy Technology Data Exchange (ETDEWEB)

    Moere, H.; Falk, R.; Svedjemark, G.A. [Swedish Radiation Protection Inst., Stockholm (Sweden); Becker, W.; Brugaard Konde, Aa. [National Food Administration, Uppsala (Sweden)


    During the autumn of 1994 an investigation of foodstuffs has been accomplished to assess the average intake of {sup 137}Cs by the Swedish population due to the Chernobyl accident. A standardized food basket has been collected from two grocers in 10 localities, of which the majority came from areas with the highest fallout. The estimated maximum intake of {sup 137}Cs was 815 Bq/year in the inland of the county of Vaesterbotten. The population weighted average intake for the fallout affected counties was 435 Bq/year. The rest of the county received an intake of 235 Bq/year. The population weighted average of the intake for the whole county was estimated to 274 Bq/year. From this intake the calculated body burden would be 1.3 Bq/kg for the average citizen. Whole-body measurements of a sample of the population gave 2.0 Bq/kg. A plausible explanation would be that 40% of the intake of {sup 137}Cs can have its origin from the 10% of the consumption of foodstuffs that are home produced or collected for the average individual in Sweden. The average intake of 274 Bq/year gives a committed effective dose equivalent of 3.6 {mu}Sv. 6 refs, 10 tabs.

  6. Changes in the epidemiology of acute appendicitis and appendectomy in Danish children 1996-2004

    DEFF Research Database (Denmark)

    Andersen, S B; Paerregaard, A; Larsen, K


    PURPOSE: Aim of the study was to describe changes in the epidemiology of acute appendicitis in Danish children between 0-19 years of age for the period 1996-2004. METHODS: The study was based on discharge diagnoses taken from the Danish National Patient Registry of all 28 274 patients with a diag......PURPOSE: Aim of the study was to describe changes in the epidemiology of acute appendicitis in Danish children between 0-19 years of age for the period 1996-2004. METHODS: The study was based on discharge diagnoses taken from the Danish National Patient Registry of all 28 274 patients...... with a diagnosis of acute uncomplicated or complicated appendicitis, and/or a registered procedure code of appendectomy. These data were computed together with data on the background population, and incidences were calculated. RESULTS: A significant decrease in the incidence of acute uncomplicated appendicitis...... was found for all age groups (range, 13-36%). The decrease was present for both sexes, but most prominent in girls. The incidence of complicated acute appendicitis decreased by 10%. CONCLUSION: The incidence of acute appendicitis is declining. The incidence of uncomplicated appendicitis appears...

  7. Occupational exposure in prostate permanent implants with I-125 seeds

    Energy Technology Data Exchange (ETDEWEB)

    Fdez Garcia, J.; Luna, V.; Sancho, J. M. g.; Martinez, J.; Galiano, P. S.; Jimenez, I.; Prada, P.; Juan, G.; Vivanco, J.


    Prostate brachytherapy is one of the techniques increasing faster in the environment of the radiotherapy and will probably go on increasing in the future. There are two forms in their use; by means of remote afterloading high dose rate (HDR) with Ir-192 radioactive sources or by means of permanent implant by manual/automatic afterloading of low dose rate (LDR) with seeds of I-125 or Pd-103. Iodine-125 has a half life of 59.4 days and it decays by electron capture with emissions of characteristic photons and electrons. The electrons are absorbed by the titanium wall of the I-125 seed. The principal photon emissions are 27.4 and 31.4 keV X-rays and a 35.5 keV gamma ray. Besides 22.1 and 25.2 keV fluorescent X-rays are also emitted resulting from interactions of the iodine-125 photons with the silver rod. The resulting average photon energy is approximately 27.4 keV. (Author)

  8. Information and shared decision-making are top patients' priorities

    Directory of Open Access Journals (Sweden)

    Bronstein Alexander


    Full Text Available Abstract Background The profound changes in medical care and the recent stress on a patient-centered approach mandate evaluation of current patient priorities. Methods Hospitalized and ambulatory patients at an academic medical center in central Israel were investigated. Consecutive patients (n = 274 indicated their first and second priority for a change or improvement in their medical care out of a mixed shortlist of 6 issues, 3 related to patient-physician relationship (being better informed and taking part in decisions; being seen by the same doctor each time; a longer consultation time and 3 issues related to the organizational aspect of care (easier access to specialists/hospital; shorter queue for tests; less charges for drugs. Results Getting more information from the physician and taking part in decisions was the most desirable patient choice, selected by 27.4% as their first priority. The next choices – access and queue – also relate to more patient autonomy and control over that of managed care regulations. Patients studied were least interested in continuity of care, consultation time or cost of drugs. Demographic or clinical variables were not significantly related to patients' choices. Conclusion Beyond its many benefits, being informed by their doctor and shared decision making is a top patient priority.

  9. John Day River Subbasin Fish Habitat Enhancement Project, 1991 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    Neal, Jeff A.; Jerome, James P.; Delano, Kenneth H.


    The purpose of the John Day Fish Habitat Enhancement Program is to enhance production of indigenous wild stocks of spring chinook and summer steelhead within the subbasin through habitat enhancement and access improvement. The John Day River system supports the largest remaining wild runs of spring chinook salmon and summer steelhead in northeast Oregon. It is the goal of this program to preserve and enhance the unique genetic component of the stocks. By attaining this goal we will be able to rebuild fish runs in other Columbia River tributaries in the future, if desired. During 1991, 5 leases were signed adding 5.25 miles of stream to the program. Fence construction included 9.95 miles of riparian fence and 15 livestock water crossings. We constructed 3 log wiers for adult salmon holding, added 280 ft. of new channel, and placed 274 fish habitat boulders, 6 trees and 31 rootwads for juvenile rearing. We constructed 15 stream deflectors and 274 linear feet of bank riprap for streambank stabilization.

  10. 以修剪桑树枝条作食用菌原料试验研究%Study on Taking Pruning Mulberry Branches as Raw Material for Edible Mushrooms

    Institute of Scientific and Technical Information of China (English)

    王国书; 冉隆俊; 刘晓会; 何朝荣


    In this paper, the conventional wood was replaced by mulberry branch as raw material for edible mushrooms. The results showed that, compared to the conventional wood, using mulberry branch to produce black fungus and mushroom, the yield per bag were increased by 7.14% and 11.9%, respectively, and the net income per bag were 0.99, 2.74 Yuan, which were significantly enhanced by 4.2% and 47.8% respectively.%以修剪桑枝代替常规木材作食用菌原料,试验结果表明,用桑枝培育黑木耳、香菇,单个菌袋出菇量分别比用常规木材高7.14%、11.9%,单个菌袋纯收入0.99、2.74元,比用常规木材增收4.2%、47.8%,经济效益十分显著。

  11. Holter monitoring to detect silent atrial fibrillation in high-risk subjects: the Perugia General Practitioner Study. (United States)

    Salvatori, Valentina; Becattini, Cecilia; Laureti, Stefano; Baglioni, Gregorio; Germini, Fabrizio; Grilli, Piero; Guercini, Francesco; Filippucci, Esmeralda; Agnelli, Giancarlo


    Atrial fibrillation (AF) is diagnosed for the first time in about 5 % of patients admitted for acute ischemic stroke. Advanced aged and arterial hypertension are risk factors for AF. We evaluated the prevalence of silent AF in subjects with advanced age and systemic arterial hypertension. Subjects of both gender, aged 65 years or more with systemic arterial hypertension were randomly identified from the patient lists of the participating general practitioners in the Perugia area, in Italy. Study subjects underwent baseline 12-lead ECG and, if this did not show AF, 48-h Holter monitoring was performed. AF was known and confirmed by 12-lead ECG in 4 out of the 308 evaluated subjects (1.3 %). Baseline 12-lead ECG showed no cases of silent AF. Holter monitoring was performed in 300 subjects, mean age 70 ± 4. Twenty-six recordings were not evaluable for the presence of artifacts; therefore, 274 subjects were included in the analysis. Holter monitoring showed AF in 27 out of 274 subjects (10 %; 95 % confidence interval 6.4-13.5 %); AF was longer than 30 s in four of the subjects. In 56 additional subjects, Holter monitoring revealed excessive supraventricular ectopic activity (20 %; 95 % confidence interval 15.3-24.7 %). Holter monitoring was able to detect silent AF in about 10 % of subjects aged 65 or above with systemic arterial hypertension. The risk of stroke associated with screened silent AF should be carefully evaluated.

  12. Characterisation of temperature-dependent phase transitions in 2,2-trimethylenedioxy- 4,4,6,6-tetrachlorocyclotriphosphazene, N3P3Cl4[O(CH23O

    Directory of Open Access Journals (Sweden)

    Odlyha Marianne


    Full Text Available Abstract Background The crystal structure of 2,2-trimethylenedioxy-4,4,6,6-tetrachlorocyclo triphosphazene has been determined at 120, 274 and 293 K. The result at 293 K confirms the room temperature Cmc21 structure, but at the lower temperatures the space group is Pna21. Nevertheless the basic structure remains the same, with only small displacements of the atoms, amounting to an average of 25 pm between 120 and 293 K. Results X-ray diffraction and DSC results indicate that the phase transition takes place in two steps between 274 – 293 K and provides an understanding of previous NQR results. In the intermediate temperature range the molecules are displaced from their room temperature positions in such a way as to give an average structure with Cmc21 symmetry. Conclusion The overall phase transition is consistent with the occurrence of a soft lattice mode at room temperature in which a large displacement of the molecule in the x-direction is coupled with a flexing motion about an axis defined by the nitrogen atoms in the N1 and N3 positions.

  13. Different Clinical Utility of Oropharyngeal Bacterial Screening prior to Percutaneous Endoscopic Gastrostomy in Oncological and Neurological Patients

    Directory of Open Access Journals (Sweden)

    Radek Kroupa


    Full Text Available Background. The aim of this study was to monitor oropharyngeal bacterial colonization in patients indicated for percutaneous endoscopic gastronomy (PEG. Methods. Oropharyngeal swabs were obtained from patients prior to PEG placement. A development of peristomal infection was evaluated. The analysis of oropharyngeal and peristomal site pathogens was done. Results. Consecutive 274 patients referred for PEG due to neurological disorder or cancer completed the study. Oropharyngeal colonization with pathogens was observed in 69% (190/274, dominantly in the neurologic subgroup of patients (P < 0.001. Peristomal infection occurred in 30 (10.9% of patients and in 57% of them the correlation between oropharyngeal and peristomal agents was present. The presence of oropharyngeal pathogens was assessed as an important risk factor for the development of peristomal infection only in oncological patients (OR = 8.33, 95% CI: 1.66–41.76. Despite a high prevalence of pathogens in neurological patients, it did not influence the risk of peristomal infection with the exception for methicillin resistant Staphylococcus aureus (MRSA carriers (OR 4.5, 95% CI: 1.08–18.76. Conclusion. During oropharyngeal microbial screening prior to the PEG insertion, the detection of pathogens may be a marker of the increased risk of peristomal infection in cancer patients only. In neurological patients the benefit of the screening is limited to the detection of MRSA carriers.

  14. Anti-HBe阳性慢性乙型肝炎患者与Anti-HBs阳性者PD-1及其配体的变化与意义%Clinical significance of peripheral blood PD-1 and its ligands in patients with anti-HBe positive CHB =or anti-HBs positive of normal ALT

    Institute of Scientific and Technical Information of China (English)

    骆华; 杨建杰; 骆方军


    目的 分析丙氨酸氨基转移酶(ALT)正常的血清Anti-HBe阳性的慢性乙型肝炎(CHB)患者与Anti-HBs阳性者外周血程序性死亡分子-1(PD-1,CD279)及其配体(CD274和CD273)的变化并探讨其临床意义.方法 分别选择23例、22例和25例ALT正常的血清Anti-HBe阳性的CHB患者、Anti-HBs阳性者和对照者.采用流式细胞术检测其外周血淋巴细胞CD279、CD274和CD273的表达水平.用多元方差分析比较各组的差异.结果 CD279在对照组、Anti-HBe阳性组和Anti-HBs阳性组的表达水平分别为:(33.3±5.4)%、(48.0±9.1)%、(42.8±9.0)%.CD274在对照组、Anti-HBe阳性组和Anti-HBs阳性组的表达水平分别为:(59.4±4.4)%、(71.3±10.3)%、(62.9±10.2)%.CD273在对照组、Anti-HBe阳性组和Anti-HBs阳性组的表达水平分别为:(5.3±2.2)%、(15.6±5.3)%、(5.1±1.0)%.从Anti-HBe阳性组到Anti-HBs阳性组再到正常对照组,CD279和CD274表达水平呈逐渐下降趋势.3个因变量在总体差异有统计学意义(Pillai迹=0.988,F=3090.105,P=0.000),η偏平方为0.458.Anti-HBs阳性组的CD273表达水平与对照组比较,其差异无统计学意义(P=0.082);其他组两两比较,差异均有统计学意义(P<0.01).结论 对于ALT正常的Anti-HBe阳性的CHB患者与Anti-HBs阳性者进行免疫状况的评估是必要的.监测HBeAg血清学转换的CHB患者或Anti-HBs阳性者外周血PD-1及其配体的变化,可更好地了解HBV感染后的病程变化,从而改善HBV感染者的预后.%Objective To study the clinical significance of peripheral blood PD-1 (CD279) and its ligands(CD274 and CD273)between patients with anti-HBe positive chronic hepatitis B (CHB) or anti-HBs positive group of normal glutamic acid alanine aminotransferase (ALT).Methods A total of 70 subjects of normal ALT,including 23 patients with anti-HBe positive,22 anti-HBs positive and 25 normal controls,were enrolled.The expression level of CD279,CD274 and CD273 in peripheral

  15. Clinical impact of hyperattenuation of adrenal glands on contrast-enhanced computed tomography of polytraumatised patients

    Energy Technology Data Exchange (ETDEWEB)

    Schek, J.; Klasen-Sansone, J.; Heusch, P.; Kroepil, P.; Antoch, G.; Lanzman, R.S. [University Dusseldorf, Medical Faculty, Department of Diagnostic and Interventional Radiology, Dusseldorf (Germany); Macht, S. [Radiologie Koeln-Nord, Koeln (Germany); Witte, I. [University Dusseldorf, Medical Faculty, Department of Trauma and Hand Surgery, Dusseldorf (Germany)


    To evaluate the prognostic value of hyperattenuating adrenal glands on contrast-enhanced CT of polytraumatised patients. Two hundred ninety-two patients (195 men and 97 women, mean age 45.3 ± 23.3 years) were included in this retrospective study. CT examinations were performed 60 s after intravenous injection of contrast material. Image analysis was performed by two radiologists. Patients were assigned to one of two groups according to the attenuation of the adrenal gland [group 1: adrenal glands ≥ inferior vena cava (IVC); group 2: adrenal glands < IVC]. Eighteen patients (42.2 years ± 24.2) were assigned to group 1 and 274 patients (48.4 years ± 22.4) to group 2. The average adrenal density was 150.8 ± 36.1 HU in group 1 and 83.7 ± 23.6 HU in group 2 (P < 0.0001). Eight of the 18 patients in group 1 (44.4 %) and 33 of the 274 patients in group 2 (12.4 %) died during hospitalisation (P < 0.05). Mean adrenal enhancement was significantly higher in patients who died (101.9 ± 40.6 HU) compared with survivors (86.1 ± 27.0 HU; P < 0.001). Hyperattenuation of adrenal glands is associated with a higher mortality rate in polytraumatised patients and may serve as a predictor of poor clinical outcome. (orig.)

  16. Semi-empirical formula for spontaneous fission half life time

    Energy Technology Data Exchange (ETDEWEB)

    Santhosh, K.P., E-mail: [School of Pure and Applied Physics, Kannur University, Payyanur Campus 670 327 (India); Biju, R.K.; Sahadevan, Sabina [P G Department of Physics and Research Centre, Payyanur College, Payyanur 670 327 (India)


    A new semi-empirical formula is proposed for determining the spontaneous fission half lives, which works well for the mass region from {sup 232}Th to {sup 286}114. The computed spontaneous fission half life times are also compared with other semi-empirical formula predictions. The alpha decay half lives are systematically computed for heavy and super heavy region with proton numbers varying from 90<=Z<=122 using Coulomb and Proximity Potential Model. The comparison between computed alpha decay half lives and the present spontaneous fission semi-empirical formula predictions of even-even isotopes with Z=90-122 are studied. It is found that in super heavy region the isotopes {sup 270-274}Ds, {sup 272-278}112, {sup 272-282}114, {sup 274-292}116, {sup 276-298}118, {sup 276-308}120 and {sup 278-314}122 will survive fission and can be synthesized and identified via alpha decay.

  17. Empirical study of simulated two-planet microlensing events

    Energy Technology Data Exchange (ETDEWEB)

    Zhu, Wei; Gould, Andrew; Penny, Matthew [Department of Astronomy, The Ohio State University, 140 West 18th Avenue, Columbus, OH 43210 (United States); Mao, Shude [National Astronomical Observatories, Chinese Academy of Sciences, 20A Datun Road, Chaoyang District, Beijing 100012 (China); Gendron, Rieul, E-mail: [Jodrell Bank Centre for Astrophysics, University of Manchester, Alan Turing Building, Manchester M13 9PL (United Kingdom)


    We undertake the first study of two-planet microlensing models recovered from simulations of microlensing events generated by realistic multiplanet systems in which 292 planetary events, including 16 two-planet events, were detected from 6690 simulated light curves. We find that when two planets are recovered, their parameters are usually close to those of the two planets in the system most responsible for the perturbations. However, in 1 of the 16 examples, the apparent mass of both detected planets was more than doubled by the unmodeled influence of a third, massive planet. This fraction is larger than but statistically consistent with the roughly 1.5% rate of serious mass errors due to unmodeled planetary companions for the 274 cases from the same simulation in which a single planet is recovered. We conjecture that an analogous effect due to unmodeled stellar companions may occur more frequently. For 7 out of 23 cases in which two planets in the system would have been detected separately, only one planet was recovered because the perturbations due to the two planets had similar forms. This is a small fraction (7/274) of all recovered single-planet models, but almost a third of all events that might plausibly have led to two-planet models. Still, in these cases, the recovered planet tends to have parameters similar to one of the two real planets most responsible for the anomaly.

  18. Lysyl Oxidase Gene G473A Polymorphism and Cigarette Smoking in Association with a High Risk of Lung and Colorectal Cancers in a North Chinese Population

    Directory of Open Access Journals (Sweden)

    Guoli Wang


    Full Text Available The relationship among the lysyl oxidase (LOX G473A single nucleotide polymorphism (SNP, cigarette smoking and lung, colorectal, colon and rectum cancer susceptibility was studied in 200 cases of lung cancer, 335 cases of colorectal cancer including 130 cases of colon cancer and 205 cases of rectum cancer, and 335 healthy people in Tangshan, China. Peripheral blood DNA samples were collected, DNA sequencing and polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP performed, followed by multivariate logistic regression analysis. In comparison to LOX473GG genotype carriers, individuals with LOX473AA exhibited a higher susceptibility to lung, colon-rectum, colon, and rectum cancers with OR values amounting to 3.84-, 2.74-, 2.75-, and 2.74-fold of the control, respectively. In the LOX 473AA-positive population, females were more susceptible than males to carcinogenesis with OR values (female vs. male: 5.25 vs. 3.23, 2.29 vs. 1.51, 2.27 vs. 1.45, and 2.25 vs. 1.53, respectively, for lung, colon-rectum combined, colon, and rectum cancers. LOX G473A polymorphism apparently elevated human sensitivity to cigarette smoking carcinogens for eliciting cancers in the lung and colon only. Thus, LOX G473A polymorphism positively correlates with carcinogenesis and it may be used as an ideal intrinsic biomarker for prediction or diagnosis of carcinogenesis in humans.

  19. Methanolysis of Carica papaya Seed Oil for Production of Biodiesel

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    Foluso O. Agunbiade


    Full Text Available The future of fossil fuel sources of energy has necessitated the need to search for renewable alternatives. Thus, Carica papaya seed oil (CPSO was employed as feedstock for the production of biodiesel by methanolysis. The seed was obtained locally, dried, and extracted with n-hexane. The CPSO was analyzed for specific gravity, viscosity, iodine value, and saponification value, among others using standard methods. The oil was transesterified by two-stage catalysis with oil to methanol mole ratio of 1 : 9. The biodiesel produced was subjected to standard fuel tests. The seed has an oil yield of 31.2% which is commercially viable. The kinematic viscosity of the oil at 313 K was 27.4 mm2s−1 while that of Carica papaya oil methylester (CPOME was reduced to 3.57 mm2s−1 and the specific gravity was 0.84 comparable with other seed-oil biodiesels and number 2 diesel. Other oil properties were compared favourably with seed oils already documented for biodiesel synthesis. CPOME’s cloud and pour points were 275 K and 274 K, respectively, and relatively higher than other biodiesels and number 2 diesel. CPOME exhibits moderate corrosion of copper strip. The methanolysis improved the fuel properties of the CPOME similar to other biodiesels. CPSO therefore exhibits a potential for biodiesel production.

  20. 反相高效液相色谱法测定烟草中的茄尼醇%Determination of Solanesol in Tobacco by RP-HPLC

    Institute of Scientific and Technical Information of China (English)

    舒俊生; 陈开波; 徐志强; 毛健


    A simple and rapid method was developed for determination of solanesol in tobacco by RP-HPLC and the saponification process was optimized. The solanesol content was quantitatively determined with the external standard method. The results indicated that the optimum saponification process was as follows: KOH -methanol solution 0.5 mol/L, of saponification temperature 30 ℃, and the saponification time 30 minutes. The method had good linearity with correlation coefficient of 0.9999. The limit of detection based on signal-to-noise ratio of 3 was 27.4 ng. The recovery of solanesol in tobacco was 99% with RSD of 0.41%.%采用反相高效液相色谱测定烟草中的茄尼醇,采用外标法进行定量,确定了色谱分离的条件,并通过皂化提取实验确定了茄尼醇最佳皂化条件:58℃、0.6 mol/L KOH甲醇溶液皂化35 min.该法具有良好的线性(相关系数为0.9999),检测限为27.4 ng(S/N=3),加标回收率为99%,方法的RSD为0.41%,方法简单、准确.