WorldWideScience

Sample records for blind test results

  1. Wind turbine wake interactions; results from blind tests

    Science.gov (United States)

    Krogstad, Per-Åge; Sætran, Lars

    2015-06-01

    Results from three "Blind test" Workshops on wind turbine wake modeling are presented. While the first "Blind test" (BT1, 2011) consisted of a single model turbine located in a large wind tunnel, the complexity was increased for each new test in order to see how various models performed. Thus the next "Blind test" (BT2, 2012) had two turbines mounted in-line. This is a crucial test for models intended to predict turbine performances in a wind farm. In the last "Blind test" (BT3, 2013) the two turbines were again mounted in-line, but offset sideways so that the rotor of the downstream turbine only intersected half the wake from the upstream turbine. This case produces high dynamic loads and strong asymmetry in the wake. For each "Blind test" the turbine geometry and wind tunnel environment was specified and the participants were asked to predict the turbine performances, as well as the wake development to five diameters downstream of the second turbine. For the first two tests axisymmetry could be assumed if the influence of the towers was neglected. This was not possible in BT3 and therefore only fully 3D methods could be applied. In all tests the prediction scatter was surprisingly high.

  2. LWR surveillance dosimetry improvement program: PSF metallurgical blind test results

    International Nuclear Information System (INIS)

    Kam, F.B.K.; Maerker, R.E.; Stallmann, F.W.

    1984-01-01

    The metallurgical irradiation experiment at the Oak Ridge Research Reactor Poolside Facility (ORR-PSF) was designed as a benchmark to test the accuracy of radiation embrittlement predictions in the pressure vessel wall of light water reactors on the basis of results from surveillance capsules. The PSF metallurgical Blind Test is concerned with the simulated surveillance capsule (SSC) and the simulated pressure vessel capsule (SPVC). The data from the ORR-PSF benchmark experiment are the basis for comparison with the predictions made by participants of the metallurgical ''Blind Test''. The Blind Test required the participants to predict the embrittlement of the irradiated specimen based only on dosimetry and metallurgical data from the SSC1 capsule. This exercise included both the prediction of damage fluence and the prediction of embrittlement based on the predicted fluence. A variety of prediction methodologies was used by the participants. No glaring biases or other deficiencies were found, but neither were any of the methods clearly superior to the others. Closer analysis shows a rather complex and poorly understood relation between fluence and material damage. Many prediction formulas can give an adequate approximation, but further improvement of the prediction methodology is unlikely at this time given the many unknown factors. Instead, attention should be focused on determining realistic uncertainties for the predicted material changes. The Blind Test comparisons provide some clues for the size of these uncertainties. In particular, higher uncertainties must be assigned to materials whose chemical composition lies outside the data set for which the prediction formula was obtained. 16 references, 14 figures, 5 tables

  3. Lactose and fructose malabsorption in children with recurrent abdominal pain: results of double-blinded testing.

    Science.gov (United States)

    Gijsbers, C F M; Kneepkens, C M F; Büller, H A

    2012-09-01

    To investigate malabsorption of lactose and fructose as causes of recurrent abdominal pain (RAP). In 220 children (128 girls, mean age 8,8 [4.1-16.0] years) with RAP, hydrogen breath tests (H(2) BT; abnormal if ΔH(2) > 30 ppm) were performed with lactose and fructose. Disappearance of RAP with elimination, recurrence with provocation and disappearance with re-elimination, followed by a 6-month pain-free follow-up, were considered indicative of a causal relation with RAP. For definite proof, a double-blinded placebo-controlled (DBPC) provocation was performed. Malabsorption of lactose was found in 57 of 210, of fructose in 79 of 121 patients. Pain disappeared upon elimination in 24/38 patients with lactose malabsorption, and in 32/49 with fructose malabsorption. Open provocation with lactose and fructose was positive in 7/23 and 13/31 patients. DBPC provocation in 6/7 and 8/13 patients was negative in all. However, several children continued to report abdominal symptoms upon intake of milk or fructose. Lactose intolerance nor fructose intolerance could be established as causes of RAP, according to preset criteria including elimination, open provocation and DBPC provocation. However, in clinical practice, persistent feeling of intolerance in some patients should be taken seriously and could warrant extended elimination with repeated challenges. © 2012 The Author(s)/Acta Paediatrica © 2012 Foundation Acta Paediatrica.

  4. Internet-accessed sexually transmitted infection (e-STI testing and results service: A randomised, single-blind, controlled trial.

    Directory of Open Access Journals (Sweden)

    Emma Wilson

    2017-12-01

    Full Text Available Internet-accessed sexually transmitted infection testing (e-STI testing is increasingly available as an alternative to testing in clinics. Typically this testing modality enables users to order a test kit from a virtual service (via a website or app, collect their own samples, return test samples to a laboratory, and be notified of their results by short message service (SMS or telephone. e-STI testing is assumed to increase access to testing in comparison with face-to-face services, but the evidence is unclear. We conducted a randomised controlled trial to assess the effectiveness of an e-STI testing and results service (chlamydia, gonorrhoea, HIV, and syphilis on STI testing uptake and STI cases diagnosed.The study took place in the London boroughs of Lambeth and Southwark. Between 24 November 2014 and 31 August 2015, we recruited 2,072 participants, aged 16-30 years, who were resident in these boroughs, had at least 1 sexual partner in the last 12 months, stated willingness to take an STI test, and had access to the internet. Those unable to provide consent and unable to read English were excluded. Participants were randomly allocated to receive 1 text message with the web link of an e-STI testing and results service (intervention group or to receive 1 text message with the web link of a bespoke website listing the locations, contact details, and websites of 7 local sexual health clinics (control group. Participants were free to use any other services or interventions during the study period. The primary outcomes were self-reported STI testing at 6 weeks, verified by patient record checks, and self-reported STI diagnosis at 6 weeks, verified by patient record checks. Secondary outcomes were the proportion of participants prescribed treatment for an STI, time from randomisation to completion of an STI test, and time from randomisation to treatment of an STI. Participants were sent a £10 cash incentive on submission of self-reported data. We

  5. Sound lateralization test in adolescent blind individuals.

    Science.gov (United States)

    Yabe, Takao; Kaga, Kimitaka

    2005-06-21

    Blind individuals require to compensate for the lack of visual information by other sensory inputs. In particular, auditory inputs are crucial to such individuals. To investigate whether blind individuals localize sound in space better than sighted individuals, we tested the auditory ability of adolescent blind individuals using a sound lateralization method. The interaural time difference discrimination thresholds of blind individuals were statistically significantly shorter than those of blind individuals with residual vision and controls. These findings suggest that blind individuals have better auditory spatial ability than individuals with visual cues; therefore, some perceptual compensation occurred in the former.

  6. Chloromethylisothiazolone/methylisothiazolone (CMI/MI) use test with a shampoo on patch-test-positive subjects. Results of a multicentre double-blind crossover trial

    DEFF Research Database (Denmark)

    Frosch, P J; Lahti, A; Hannuksela, M

    1995-01-01

    A randomized, multicentre, double-blind, 2-period crossover study with 2 shampoos was performed on subjects patch-test-positive to 100 ppm CMI/MI. One shampoo was preserved with 15 ppm a.i. CMI/MI, the other with 0.3% imidazolidinyl urea (IU). 27 subjects from 5 European dermatology clinics...... or cosmetic ingredient. Full ingredient labelling will ensure that this is possible. As the overall rate of adverse effects in sensitized individuals was low, studies of this nature should also be conducted for other allergens.(ABSTRACT TRUNCATED AT 250 WORDS)...

  7. Internet-accessed sexually transmitted infection (e-STI) testing and results service: A randomised, single-blind, controlled trial.

    Science.gov (United States)

    Wilson, Emma; Free, Caroline; Morris, Tim P; Syred, Jonathan; Ahamed, Irrfan; Menon-Johansson, Anatole S; Palmer, Melissa J; Barnard, Sharmani; Rezel, Emma; Baraitser, Paula

    2017-12-01

    Internet-accessed sexually transmitted infection testing (e-STI testing) is increasingly available as an alternative to testing in clinics. Typically this testing modality enables users to order a test kit from a virtual service (via a website or app), collect their own samples, return test samples to a laboratory, and be notified of their results by short message service (SMS) or telephone. e-STI testing is assumed to increase access to testing in comparison with face-to-face services, but the evidence is unclear. We conducted a randomised controlled trial to assess the effectiveness of an e-STI testing and results service (chlamydia, gonorrhoea, HIV, and syphilis) on STI testing uptake and STI cases diagnosed. The study took place in the London boroughs of Lambeth and Southwark. Between 24 November 2014 and 31 August 2015, we recruited 2,072 participants, aged 16-30 years, who were resident in these boroughs, had at least 1 sexual partner in the last 12 months, stated willingness to take an STI test, and had access to the internet. Those unable to provide consent and unable to read English were excluded. Participants were randomly allocated to receive 1 text message with the web link of an e-STI testing and results service (intervention group) or to receive 1 text message with the web link of a bespoke website listing the locations, contact details, and websites of 7 local sexual health clinics (control group). Participants were free to use any other services or interventions during the study period. The primary outcomes were self-reported STI testing at 6 weeks, verified by patient record checks, and self-reported STI diagnosis at 6 weeks, verified by patient record checks. Secondary outcomes were the proportion of participants prescribed treatment for an STI, time from randomisation to completion of an STI test, and time from randomisation to treatment of an STI. Participants were sent a £10 cash incentive on submission of self-reported data. We completed all

  8. Sociocultural theory and blind taste-tests

    Directory of Open Access Journals (Sweden)

    James Paul Gee

    2010-05-01

    Full Text Available In his entertaining 1986 book, The Real Coke, the Real Story, Thomas Oliver tells the story of the now infamous “New Coke”, a story retold in Malcolm Gladwell’s (2005 best-seller Blink. In the early 1980s, Pepsi began running commercials in which people took a sip from two glasses, not knowing which was Coke and which Pepsi. The majority preferred Pepsi. The Coca-Cola Company replicated these blind taste-tests and found the same result. Losing market share, Coke—long the dominant brand—changed its old formula and came out with “New Coke”, a soda made to a new formula, one that in a new round of blind taste-tests came out above Pepsi. But New Coke was a disaster.Consumers hated it. Coke not only returned to its old formula, but Pepsi never did overtake Coke, which remains today the dominant brand world-wide.

  9. Cholesterol testing and results

    Science.gov (United States)

    Cholesterol test results; LDL test results; VLDL test results; HDL test results; Coronary risk profile results; Hyperlipidemia-results; Lipid disorder test results; Heart disease - cholesterol results

  10. Blind pre-analysis of the main building complex WWER-440/213 Paks for comparison of analytical and experimental results obtained by explosive testing (task 7a of workplan 95/96)

    International Nuclear Information System (INIS)

    1999-01-01

    Within the research programme on Benchmark studies of seismic analysis of WWER type reactors the blind pre-analysis must be prepared for the main building complex of Paks NPP, based on given excitations derived from explosion tests. The aim of the investigation was to validate different idealization concepts (mathematical models for the idealization of the structures and the soil) as well as investigation procedures (time domain and frequency domain analysis) and finally the software tools by comparing dynamic properties (eigenfrequencies, eigenmodes, modal values) and structural response results (time histories and response spectra). This report contains results of the blind pre-analysis performed by using three dimensional idealization of the main building complex (reactor building, turbine house, galleries) by means of time and frequency domian calculation procedures

  11. Blindness resulting from orbital cellulitis following rhinoplasty.

    Science.gov (United States)

    Lee, Kyung Mook; Han, Sang Chul; Ho, Samuel Y M; Kim, Jeong Tae; Kim, Youn Hwan

    2013-05-01

    Ophthalmic complications occurring after non-ophthalmic surgery are rare. We present a case of orbital cellulitis in a 24-year-old woman, who had undergone augmentation rhinoplasty in combination with breast augmentation. Symptoms included pain, swelling, erythema and eventual loss of vision in the left eye. Intravenous administration of antibiotics did not halt the rapid progression of this infection. On the sixth postoperative day, the patient underwent left-orbital evisceration to prevent the spread of infection to other organ systems. Despite aggressive therapy, the sequela was permanent, unilateral blindness. Orbital cellulitis in aesthetic surgery is extremely rare. In patients undergoing rhinoplasties that may be prolonged due to other concomitant cosmetic procedures, aseptic preoperative preparation and careful monitoring for signs of orbital infection are recommended. Copyright © 2013 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.

  12. Testing a solar-blind pyrometer

    Science.gov (United States)

    Ballestrín, J.; Marzo, A.; Cañadas, I.; Rodríguez, J.

    2010-12-01

    Surface temperatures are key parameters in many concentrated solar radiation applications. Pyrometric temperature measurement of solar irradiated material surfaces is the alternative to contact measurement techniques, which are inadequate for measuring the temperatures of such surfaces. However, reflected solar radiation is an important uncertainty variable in this non-contact methodology. A promising method for eliminating this solar perturbation is by using centred passband filters on the atmospheric solar absorption bands, creating solar-blind pyrometric systems. A commercial pyrometer has been tested in the wavelength band at around 1.4 µm in the solar furnace at Plataforma Solar de Almería, showing its advantages and limitations. An estimation of temperature measurement uncertainty for a real case is presented with theory and experiment in agreement: the higher the temperature, the lower the uncertainty. Another experiment has shown that the pyrometer measures temperature properly even through quartz windows in this spectral range.

  13. PARENT Quick Blind Round-Robin Test Report

    Energy Technology Data Exchange (ETDEWEB)

    Braatz, Brett G. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Heasler, Patrick G. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Meyer, Ryan M. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2014-09-30

    The U.S. Nuclear Regulatory Commission has established the Program to Assess the Reliability of Emerging Nondestructive Techniques (PARENT) whose goal is to investigate the effectiveness of current and novel nondestructive examination procedures and techniques to find flaws in nickel-alloy welds and base materials. This is to be done by conducting a series of open and blind international round-robin tests on a set of piping components that include large-bore dissimilar metal welds, small-bore dissimilar metal welds, and bottom-mounted instrumentation penetration welds. The blind testing is being conducted in two segments, one is called Quick-Blind and the other is called Blind. The Quick-Blind testing and destructive analysis of the test blocks has been completed. This report describes the four Quick-Blind test blocks used, summarizes their destructive analysis, gives an overview of the nondestructive evaluation (NDE) techniques applied, provides an analysis inspection data, and presents the conclusions drawn.

  14. Blind pre-analysis of the main building complex WWER-1000 Kozloduy. Comparison of analytical and experimental results obtained by explosive testing (task 8a of workplan 96/97)

    International Nuclear Information System (INIS)

    Krutzik, N.J.

    1999-01-01

    In accordance with the 96/97 workplan of the Research Programme on 'Benchmark Studies for Seismic Analysis and Testing of WWER-Type Nuclear Power Plants', blind pre analyses were prepared for the main building complex of the WWER-1000 based on given excitations derived from explosive tests. The investigations were performed by several institutions based on various mathematical models and procedures for consideration of soil-structure interaction effects, but on the same explosive test input data recently obtained. The methods of calculation and software tools used will also be different. The aim of this investigation is to validate different idealization concepts (mathematical models for the idealization of the structures and the soil) as well as investigation procedures (time domain and frequency domain analysis) and finally the software tools by comparing structural response results (time histories and response spectra). This report contains the results of the blind pre analysis performed by Siemens using an equivalent beam model of the main building of the WWER 1000. The calculations were performed by means of a frequency domain calculation

  15. STANFORD-OHWAKI-KOHS TACTILE BLOCK DESIGN INTELLIGENCE TEST FOR THE BLIND. PART ONE-FINAL REPORT.

    Science.gov (United States)

    DAUTERMAN, WILLIAM L.; SUINN, RICHARD M.

    THIS TEST WAS DEVELOPED TO MEASURE THE INTELLIGENCE OF BLIND ADOLESCENTS AND ADULTS. SIX HUNDRED AND THIRTY BLIND SUBJECTS 14 YEARS OF AGE AND OLDER WERE USED IN REFINING AND STANDARDIZING THE NONVERBAL, PERFORMANCE OHWAKI-KOHS BLOCK DESIGN TEST FOR USE BY BLIND INDIVIDUALS IN THE UNITED STATES. RESULTS INDICATED STATISTICALLY SIGNIFICANT…

  16. Causes of childhood blindness in Malaysia: results from a national study of blind school students.

    Science.gov (United States)

    Reddy, S C; Tan, B C

    2001-01-01

    A national study was conducted in children attending six schools for the blind in Malaysia to identify the anatomical site and underlying causes of blindness (BL) and severe visual impairment (SVI), with a view to determine the potentially preventable and treatable causes so that appropriate control measures can be implemented in the future. The standardized clinical examination of eyes was performed and the findings were recorded on the WHO Prevention of Blindness Programme eye examination record form for children with blindness and low vision. A total of 358 children aged between 7 and 17 years were examined, of whom 332 (92.7%) were blind or severely visually impaired. The results relate to these 332 children. Lens was the major anatomical site (22.3%) of visual loss followed by retina (20.8%), whole globe (17.2%), cornea (15.1%), optic nerve (8.7%) and uvea (5.1%). Glaucoma was responsible for BL/SVI in 7.2% and others in 3.6% of cases. Hereditary diseases were responsible for visual loss in 29.5%, intrauterine factors in 4.5%, perinatal factors in 9% and childhood factors in 7.8% of cases. However, the aetiology was unknown in 49.1% of cases which included congenital anomalies of the globe. Childhood cataract and corneal scarring are major treatable causes of BL/SVI that can benefit from future intervention strategies. Perinatal screening for intrauterine factors and hereditary eye diseases, and appropriate interventional therapy will help in reducing the prevalence of childhood blindness.

  17. Blindness

    Science.gov (United States)

    ... Specific Prevalence Rates for Blindness by Age and Race/Ethnicity Table for 2010 U.S. Age-Specific Prevalence ... Race/Ethnicity 2010 Prevalence Rates of Blindness by Race Table for 2010 Prevalence Rates of Blindness by ...

  18. Undulator Transportation Test Results

    International Nuclear Information System (INIS)

    Wolf, Zachary

    2010-01-01

    A test was performed to determine whether transporting and handling the undulators makes any changes to their properties. This note documents the test. No significant changes to the test undulator were observed. After the LCLS undulators are tuned and fiducialized in the Magnetic Measurement Facility (MMF), they must be transported to storage buildings and transported to the tunnel. It has been established that the undulators are sensitive to temperature. We wish to know whether the undulators are also sensitive to the vibrations and shocks of transportation. To study this issue, we performed a test in which an undulator was measured in the MMF, transported to the tunnel, brought back to the MMF, and re-measured. This note documents the test and the results.

  19. Issues in Standardizing Psychometric Tests for Children Who Are Blind.

    Science.gov (United States)

    Hull, T.; Mason, H.

    1993-01-01

    This article discusses issues and difficulties encountered in efforts at the University of Birmingham (England) to standardize a new psychometric assessment tool, a tactile speed-of-information-processing test for children with blindness. The problem of defining the population on which the test is standardized is seen as particularly difficult.…

  20. Climax granite test results

    Energy Technology Data Exchange (ETDEWEB)

    Ramspott, L.D.

    1980-01-15

    The Lawrence Livermore Laboratory (LLL), as part of the Nevada Nuclear Waste Storage Investigations (NNWSI) program, is carrying out in situ rock mechanics testing in the Climax granitic stock at the Nevada Test Site (NTS). This summary addresses only those field data taken to date that address thermomechanical modeling for a hard-rock repository. The results to be discussed include thermal measurements in a heater test that was conducted from October 1977 through July 1978, and stress and displacement measurements made during and after excavation of the canister storage drift for the Spent Fuel Test (SFT) in the Climax granite. Associated laboratory and field measurements are summarized. The rock temperature for a given applied heat load at a point in time and space can be adequately modeled with simple analytic calculations involving superposition and integration of numerous point source solutions. The input, for locations beyond about a meter from the source, can be a constant thermal conductivity and diffusivity. The value of thermal conductivity required to match the field data is as much as 25% different from laboratory-measured values. Therefore, unless we come to understand the mechanisms for this difference, a simple in situ test will be required to obtain a value for final repository design. Some sensitivity calculations have shown that the temperature field is about ten times more sensitive to conductivity than to diffusivity under the test conditions. The orthogonal array was designed to detect anisotropy. After considering all error sources, anisotropic efforts in the thermal field were less than 5 to 10%.

  1. Dissociated methanol test results

    Energy Technology Data Exchange (ETDEWEB)

    Finegold, J.G.; McKinnon, J.T.

    1982-04-01

    The design and testing of an automotive fuel system that provides hydrogen-rich gases to an internal combustion engine by catalytically cracking, or dissociating, methanol on board the vehicle is described. The vaporization and dissociation of methanol absorb heat from the engine exhaust and increase the lower heating value of the fuel by approximately 22%. In addition, raising the compression ratio and burning with excess air increase the engine thermal efficiency. Engine dynamometer test results with dissociated methanol demonstrated improvement in brake thermal efficiency compared to gasoline from 30% to 100% depending on engine speed and torque. Lower speeds and torques produce the largest improvements. Maps of exhaust temperature and exhaust heat content are presented. The exhaust temperature is almost always high enough for dissociation to occur, but at lower power outputs, there is only enough exhaust energy for partial dissociation of the methanol.

  2. A SPICE Blind Test to Benchmark Global Tomographic Methods

    Science.gov (United States)

    Qin, Y.; Capdeville, Y.; Maupin, V.; Montagner, J.

    2006-12-01

    The different existing global tomographic methods result in different models of the Earth. In order to test how current imaging techniques are limited by approximations in theory and the inadequacy of data quality and coverage, we are undertaking a blind test of global inversion algorithms using complete 3D synthetic seismograms within SPICE (Seismic wave Propagation and Imaging in Complex media: a European network). First, a complex global anisotropic anelastic model has been constructed by summing the 1D reference model, deterministic and random anomalies and anisotropic crystal. This model includes 3D heterogeneities in velocity, anisotropy and attenuation at different scales in the whole mantle, as well as topography and crustal structure. In addition, the rotation and ellipticity are also included. Synthetic seismograms were generated using the Coupling Spectral Element Method with a minimum period of 32s, for a realistic distribution of 29 events and 256 stations. The synthetic seismograms have been made available to the scientific community worldwide at the IPGP website http://www.ipgp.jussieu.fr/~qyl/. Any group willing to test his tomographic technique is encouraged to download the synthetic dataset.g

  3. Results of steel containment vessel model test

    International Nuclear Information System (INIS)

    Luk, V.K.; Ludwigsen, J.S.; Hessheimer, M.F.; Komine, Kuniaki; Matsumoto, Tomoyuki; Costello, J.F.

    1998-05-01

    A series of static overpressurization tests of scale models of nuclear containment structures is being conducted by Sandia National Laboratories for the Nuclear Power Engineering Corporation of Japan and the US Nuclear Regulatory Commission. Two tests are being conducted: (1) a test of a model of a steel containment vessel (SCV) and (2) a test of a model of a prestressed concrete containment vessel (PCCV). This paper summarizes the conduct of the high pressure pneumatic test of the SCV model and the results of that test. Results of this test are summarized and are compared with pretest predictions performed by the sponsoring organizations and others who participated in a blind pretest prediction effort. Questions raised by this comparison are identified and plans for posttest analysis are discussed

  4. Poverty and Blindness in Nigeria: Results from the National Survey of Blindness and Visual Impairment.

    Science.gov (United States)

    Tafida, A; Kyari, F; Abdull, M M; Sivasubramaniam, S; Murthy, G V S; Kana, I; Gilbert, Clare E

    2015-01-01

    Poverty can be a cause and consequence of blindness. Some causes only affect the poorest communities (e.g. trachoma), and poor individuals are less likely to access services. In low income countries, cataract blind adults have been shown to be less economically active, indicating that blindness can exacerbate poverty. This study aims to explore associations between poverty and blindness using national survey data from Nigeria. Participants ≥40 years were examined in 305 clusters (2005-2007). Sociodemographic information, including literacy and occupation, was obtained by interview. Presenting visual acuity (PVA) was assessed using a reduced tumbling E LogMAR chart. Full ocular examination was undertaken by experienced ophthalmologists on all with PVA Health Organization guidelines. Households were categorized into three levels of poverty based on literacy and occupation at household level. A total of 569/13,591 participants were blind (PVA poor households (25.3%). Spectacle coverage was 3 times lower in poor than affluent households (2.4% vs. 7.5%). In Nigeria, blindness is associated with poverty, in part reflecting lower access to services. Reducing avoidable causes will not be achieved unless access to services improves, particularly for the poor and women.

  5. Pressure locking test results

    International Nuclear Information System (INIS)

    DeWall, K.G.; Watkins, J.C.; McKellar, M.G.; Bramwell, D.

    1996-01-01

    The U.S. Nuclear Regulatory Commission (NRC), Office of Nuclear Regulatory Research, is funding the Idaho National Engineering Laboratory (INEL) in performing research to provide technical input for their use in evaluating responses to Generic Letter 95-07, open-quotes Pressure Locking and Thermal Binding of Safety-Related Power-Operated Gate Valves.close quotes Pressure locking and thermal binding are phenomena that make a closed gate valve difficult to open. This paper discusses only the pressure locking phenomenon in a flexible-wedge gate valve; we will publish the results of our thermal binding research at a later date. Pressure locking can occur when operating sequences or temperature changes cause the pressure of the fluid in the bonnet (and, in most valves, between the discs) to be higher than the pressure on the upstream and downstream sides of the disc assembly. This high fluid pressure presses the discs against both seats, making the disc assembly harder to unseat than anticipated by the typical design calculations, which generally consider friction at only one of the two disc/seat interfaces. The high pressure of the bonnet fluid also changes the pressure distribution around the disc in a way that can further contribute to the unseating load. If the combined loads associated with pressure locking are very high, the actuator might not have the capacity to open the valve. The results of the NRC/INEL research discussed in this paper show that the relationship between bonnet pressure and pressure locking stem loads appears linear. The results also show that for this valve, seat leakage affects the bonnet pressurization rate when the valve is subjected to thermally induced pressure locking conditions

  6. Pressure locking test results

    Energy Technology Data Exchange (ETDEWEB)

    DeWall, K.G.; Watkins, J.C.; McKellar, M.G.; Bramwell, D. [Idaho National Engineering Lab., Idaho Falls, ID (United States)] [and others

    1996-12-01

    The U.S. Nuclear Regulatory Commission (NRC), Office of Nuclear Regulatory Research, is funding the Idaho National Engineering Laboratory (INEL) in performing research to provide technical input for their use in evaluating responses to Generic Letter 95-07, {open_quotes}Pressure Locking and Thermal Binding of Safety-Related Power-Operated Gate Valves.{close_quotes} Pressure locking and thermal binding are phenomena that make a closed gate valve difficult to open. This paper discusses only the pressure locking phenomenon in a flexible-wedge gate valve; the authors will publish the results of their thermal binding research at a later date. Pressure locking can occur when operating sequences or temperature changes cause the pressure of the fluid in the bonnet (and, in most valves, between the discs) to be higher than the pressure on the upstream and downstream sides of the disc assembly. This high fluid pressure presses the discs against both seats, making the disc assembly harder to unseat than anticipated by the typical design calculations, which generally consider friction at only one of the two disc/seat interfaces. The high pressure of the bonnet fluid also changes the pressure distribution around the disc in a way that can further contribute to the unseating load. If the combined loads associated with pressure locking are very high, the actuator might not have the capacity to open the valve. The results of the NRC/INEL research discussed in this paper show that the relationship between bonnet pressure and pressure locking stem loads appears linear. The results also show that for this valve, seat leakage affects the bonnet pressurization rate when the valve is subjected to thermally induced pressure locking conditions.

  7. Blindness

    Science.gov (United States)

    ... doctors may do surgery to remove it. Is Learning Different? A baby who is blind can still ... do amazing things in many different fields, including music, the arts, and even sports. Serious vision problems ...

  8. Clinical testing of pre-pandemic live attenuated A/H5N2 influenza candidate vaccine in adult volunteers: results from a placebo-controlled, randomized double-blind phase I study.

    Science.gov (United States)

    Rudenko, Larisa; Kiseleva, Irina; Stukova, Marina; Erofeeva, Marianna; Naykhin, Anatoly; Donina, Svetlana; Larionova, Natalie; Pisareva, Maria; Krivitskaya, Vera; Flores, Jorge

    2015-09-22

    This study describes a double-blinded randomized placebo-controlled phase I clinical trial of A/H5N2 live attenuated influenza vaccine in healthy volunteers. Two doses of vaccine or placebo were administered intranasally to 30 and 10 subjects, respectively. Nasal swabs were examined for vaccine shedding and local antibody responses; serum samples were tested for binding, hemagglutinating and neutralizing antibodies and peripheral blood mononuclear cells were tested for cell-mediated immune responses. The vaccine was well tolerated and not associated with increased rates of adverse events or the occurrence of serious adverse events. Influenza virus was detected in nasal swabs on the first day in the majority of volunteers (93%), while 17% of volunteers tested positive on the second, none on the third day or later following the first vaccination; lower frequency of shedding was observed after the second vaccination. The vaccine was immunogenic as assessed four weeks after the second dose, with 37.9% and 48.3% of subjects seroconverting by hemagglutination inhibition and neutralization assays, respectively. An immune response was observed in 96.6% subjects that received A/H5N2 LAIV in at least one of the assays conducted. None of the placebo recipients exhibited a response in any of the assays. The A/H5N2 vaccine was safe, well tolerated, and immunogenic in healthy adults. ClinicalTrials.gov NCT01719783. Copyright © 2015 Elsevier Ltd. All rights reserved.

  9. Blind Test of Physics-Based Prediction of Protein Structures

    Science.gov (United States)

    Shell, M. Scott; Ozkan, S. Banu; Voelz, Vincent; Wu, Guohong Albert; Dill, Ken A.

    2009-01-01

    We report here a multiprotein blind test of a computer method to predict native protein structures based solely on an all-atom physics-based force field. We use the AMBER 96 potential function with an implicit (GB/SA) model of solvation, combined with replica-exchange molecular-dynamics simulations. Coarse conformational sampling is performed using the zipping and assembly method (ZAM), an approach that is designed to mimic the putative physical routes of protein folding. ZAM was applied to the folding of six proteins, from 76 to 112 monomers in length, in CASP7, a community-wide blind test of protein structure prediction. Because these predictions have about the same level of accuracy as typical bioinformatics methods, and do not utilize information from databases of known native structures, this work opens up the possibility of predicting the structures of membrane proteins, synthetic peptides, or other foldable polymers, for which there is little prior knowledge of native structures. This approach may also be useful for predicting physical protein folding routes, non-native conformations, and other physical properties from amino acid sequences. PMID:19186130

  10. A blind test of nondestructive underground void detection by ground penetrating radar (GPR)

    Science.gov (United States)

    Lai, Wallace W. L.; Chang, Ray K. W.; Sham, Janet F. C.

    2018-02-01

    Blind test/experiment is widely adopted in various scientific disciplines like medicine drug testing/clinical trials/psychology, but not popular in nondestructive testing and evaluation (NDTE) nor near-surface geophysics (NSG). This paper introduces a blind test of nondestructive underground void detection in highway/pavement using ground penetrating radar (GPR). Purpose of which is to help the Highways Department (HyD) of the Hong Kong Government to evaluate the feasibility of large-scale and nationwide application, and examine the ability of appropriate service providers to carry out such works. In the past failure case of such NDTE/NSG based on lowest bid price, it is not easy to know which part(s) in SWIMS (S - service provider, i.e. people; W - work procedure; I - instrumentation; M - materials in the complex underground; S - specifications by client) fails, and how it/they fail(s). This work attempts to carry out the blind test by burying fit balls (as voids) under a site with reinforced concrete road and paving block by PolyU team A. The blind test about the void centroid, spread and cover depth was then carried out by PolyU team B without prior information given. Then with this baseline, a marking scheme, acceptance criteria and passing mark were set to test six local commercial service providers, determine their scores and evaluate the performance. A pass is a prerequisite of the award of a service contract of similar nature. In this first attempt of the blind test, results were not satisfactory and it is concluded that 'S-service provider' and 'W-work procedure' amongst SWIMS contributed to most part of the unsatisfactory performance.+

  11. ORNL evaluation of the ORR-PSF metallurgical experiment and blind test

    International Nuclear Information System (INIS)

    Stallmann, F.W.

    1984-01-01

    A methodology is described to evaluate the dosimetry and metallurgical data from the two-year ORR-PSF metallurgical irradiation experiment. The first step is to obtain a three-dimensional map of damage exposure parameter values based on neutron transport calculations and dosimetry measurements which are obtained by means of the LSL-M2 adjustment procedure. Metallurgical test data are then combined with damage parameter, temperature, and chemistry information to determine the correlation between radiation and steel embrittlement in reactor pressure vessels including estimates for the uncertainties. Statistical procedures for the evaluation of Charpy data, developed earlier, are used for this investigation. The data obtained in this investigation provide a benchmark against which the predictions of the PSF Blind Test can be compared. The results of this investigation and the Blind Test comparison are discussed

  12. Verifiable Measurement-Only Blind Quantum Computing with Stabilizer Testing.

    Science.gov (United States)

    Hayashi, Masahito; Morimae, Tomoyuki

    2015-11-27

    We introduce a simple protocol for verifiable measurement-only blind quantum computing. Alice, a client, can perform only single-qubit measurements, whereas Bob, a server, can generate and store entangled many-qubit states. Bob generates copies of a graph state, which is a universal resource state for measurement-based quantum computing, and sends Alice each qubit of them one by one. Alice adaptively measures each qubit according to her program. If Bob is honest, he generates the correct graph state, and, therefore, Alice can obtain the correct computation result. Regarding the security, whatever Bob does, Bob cannot get any information about Alice's computation because of the no-signaling principle. Furthermore, malicious Bob does not necessarily send the copies of the correct graph state, but Alice can check the correctness of Bob's state by directly verifying the stabilizers of some copies.

  13. MITG test procedure and results

    International Nuclear Information System (INIS)

    Eck, M.E.; Mukunda, M.

    1983-01-01

    Elements and modules for Radioisotope Thermoelectric Generator have been performance tested since the inception of the RTG program. These test articles seldom resembled flight hardware and often lacked adequate diagnostic instrumentation. Because of this, performance problems were not identified in the early stage of program development. The lack of test data in an unexpected area often hampered the development of a problem solution. A procedure for conducting the MITG Test was developed in an effort to obtain data in a systematic, unambiguous manner. This procedure required the development of extensive data acquisition software and test automation. The development of a facility to implement the test procedure, the facility hardware and software requirements, and the results of the MITG testing are the subject of this paper

  14. ISP42 (PANDA Tests) - Blind Phase Comparison Report

    International Nuclear Information System (INIS)

    Luebbesmeyer, D.; Aksan, S.N.

    2003-05-01

    The International Standard Problem (ISP) No. 45 is part of the overall ISP program of the OECD/NEA and is dedicated to the behavior of heat-up and delayed reflood of fuel elements in nuclear reactors during a hypothetical accident. ISP-45 is related to the out-of-pile bundle quench experiment QUENCH-06, performed at Forschungszentrum Karlsruhe (FZK), Germany, on December 13, 2000. Special attention was paid to hydrogen production. To assess the ability of severe accident codes to simulate processes during core heat-up and reflood at temperatures above 2000 K, the behavior of the bundle during the whole experiment should be calculated on the basis of the necessary experimental initial and boundary conditions, but without knowing further experimental details. In this so-called blind phase 21 participants from 15 nations contributed with 8 different code systems (ATHLET-CD, ICARE/CATHARE, IMPACT/SAMPSON, GENFLO, MAAP, MELCOR, SCDAPSIM, SCDAP-3D). Additionally, posttest calculations using the in-house version SCDAP/RELAP5 mod3.2.irs are used for comparison. After the end of the blind phase all measured data were made available and the participants were invited to deliver a second calculation, where this knowledge could be used (so called open phase). In this report, results of the blind calculations are presented, analyzed, and compared to experimental data. During heat-up most results do not deviate significantly from one another, except as a consequence of some obvious user errors, so that a definition of a mainstream is justified. For the quench phase the lack of adequate hydraulic modeling becomes obvious: some participants could not match the observed cool-down rates, others had to use very fine meshes to compensate code deficiencies. To overcome this insufficiency some newly developed reflood models were used in MAAP and MELCOR. In QUENCH-06, oxide layers were thick enough to protect the cladding from melting and failure below 2200 K, so that no massive hydrogen

  15. Consolidation and atmospheric drying of fine oil sand tailings : Comparison of blind simulations and field scale results

    NARCIS (Netherlands)

    Vardon, P.J.; Yao, Y.; van Paassen, L.A.; van Tol, A.F.; Sego, D.C.; Wilson, G.W.; Beier, N.A.

    2016-01-01

    This paper presents a comparison between blind predictions of field tests of atmospheric drying of mature fine tailings (MFT) presented in IOSTC 2014 and field results. The numerical simulation of the consolidation and atmospheric drying of selfweight consolidating fine material is challenging and

  16. Long-Term Results from an Epiretinal Prosthesis to Restore Sight to the Blind.

    Science.gov (United States)

    Ho, Allen C; Humayun, Mark S; Dorn, Jessy D; da Cruz, Lyndon; Dagnelie, Gislin; Handa, James; Barale, Pierre-Olivier; Sahel, José-Alain; Stanga, Paulo E; Hafezi, Farhad; Safran, Avinoam B; Salzmann, Joel; Santos, Arturo; Birch, David; Spencer, Rand; Cideciyan, Artur V; de Juan, Eugene; Duncan, Jacque L; Eliott, Dean; Fawzi, Amani; Olmos de Koo, Lisa C; Brown, Gary C; Haller, Julia A; Regillo, Carl D; Del Priore, Lucian V; Arditi, Aries; Geruschat, Duane R; Greenberg, Robert J

    2015-08-01

    Retinitis pigmentosa (RP) is a group of inherited retinal degenerations leading to blindness due to photoreceptor loss. Retinitis pigmentosa is a rare disease, affecting only approximately 100 000 people in the United States. There is no cure and no approved medical therapy to slow or reverse RP. The purpose of this clinical trial was to evaluate the safety, reliability, and benefit of the Argus II Retinal Prosthesis System (Second Sight Medical Products, Inc, Sylmar, CA) in restoring some visual function to subjects completely blind from RP. We report clinical trial results at 1 and 3 years after implantation. The study is a multicenter, single-arm, prospective clinical trial. There were 30 subjects in 10 centers in the United States and Europe. Subjects served as their own controls, that is, implanted eye versus fellow eye, and system on versus system off (native residual vision). The Argus II System was implanted on and in a single eye (typically the worse-seeing eye) of blind subjects. Subjects wore glasses mounted with a small camera and a video processor that converted images into stimulation patterns sent to the electrode array on the retina. The primary outcome measures were safety (the number, seriousness, and relatedness of adverse events) and visual function, as measured by 3 computer-based, objective tests. A total of 29 of 30 subjects had functioning Argus II Systems implants 3 years after implantation. Eleven subjects experienced a total of 23 serious device- or surgery-related adverse events. All were treated with standard ophthalmic care. As a group, subjects performed significantly better with the system on than off on all visual function tests and functional vision assessments. The 3-year results of the Argus II trial support the long-term safety profile and benefit of the Argus II System for patients blind from RP. Earlier results from this trial were used to gain approval of the Argus II by the Food and Drug Administration and a CE mark in

  17. Mobile evaporator corrosion test results

    International Nuclear Information System (INIS)

    Rozeveld, A.; Chamberlain, D.B.

    1997-05-01

    Laboratory corrosion tests were conducted on eight candidates to select a durable and cost-effective alloy for use in mobile evaporators to process radioactive waste solutions. Based on an extensive literature survey of corrosion data, three stainless steel alloys (304L, 316L, AL-6XN), four nickel-based alloys (825, 625, 690, G-30), and titanium were selected for testing. The corrosion tests included vapor phase, liquid junction (interface), liquid immersion, and crevice corrosion tests on plain and welded samples of candidate materials. Tests were conducted at 80 degrees C for 45 days in two different test solutions: a nitric acid solution. to simulate evaporator conditions during the processing of the cesium ion-exchange eluant and a highly alkaline sodium hydroxide solution to simulate the composition of Tank 241-AW-101 during evaporation. All of the alloys exhibited excellent corrosion resistance in the alkaline test solution. Corrosion rates were very low and localized corrosion was not observed. Results from the nitric acid tests showed that only 316L stainless steel did not meet our performance criteria. The 316L welded interface and crevice specimens had rates of 22.2 mpy and 21.8 mpy, respectively, which exceeds the maximum corrosion rate of 20 mpy. The other welded samples had about the same corrosion resistance as the plain samples. None of the welded samples showed preferential weld or heat-affected zone (HAZ) attack. Vapor corrosion was negligible for all alloys. All of the alloys except 316L exhibited either open-quotes satisfactoryclose quotes (2-20 mpy) or open-quotes excellentclose quotes (<2 mpy) corrosion resistance as defined by National Association of Corrosion Engineers. However, many of the alloys experienced intergranular corrosion in the nitric acid test solution, which could indicate a susceptibility to stress corrosion cracking (SCC) in this environment

  18. Effect of point-of-care CD4 cell count results on linkage to care and antiretroviral initiation during a home-based HIV testing campaign: a non-blinded, cluster-randomised trial.

    Science.gov (United States)

    Desai, Mitesh A; Okal, Dancun O; Rose, Charles E; Ndivo, Richard; Oyaro, Boaz; Otieno, Fredrick O; Williams, Tiffany; Chen, Robert T; Zeh, Clement; Samandari, Taraz

    2017-09-01

    HIV disease staging with referral laboratory-based CD4 cell count testing is a key barrier to the initiation of antiretroviral treatment (ART). Point-of-care CD4 cell counts can improve linkage to HIV care among people living with HIV, but its effect has not been assessed with a randomised controlled trial in the context of home-based HIV counselling and testing (HBCT). We did a two-arm, cluster-randomised, controlled efficacy trial in two districts of western Kenya with ongoing HBCT. Housing compounds were randomly assigned (1:1) to point-of-care CD4 cell counts (366 compounds with 417 participants) or standard-of-care (318 compounds with 353 participants) CD4 cell counts done at one of three referral laboratories serving the study catchment area. In each compound, we enrolled people with HIV not engaged in care in the previous 6 months. All participants received post-test counselling and referral for HIV care. Point-of-care test participants received additional counselling on the result, including ART eligibility if CD4 was less than 350 cells per μL, the cutoff in Kenyan guidelines. Participants were interviewed 6 months after enrolment to ascertain whether they sought HIV care, verified through chart reviews at 23 local clinics. The prevalence of loss to follow-up at 6 months (LTFU) was listed as the main outcome in the study protocol. We analysed linkage to care at 6 months (defined as 1-LTFU) as the primary outcome. All analyses were by intention to treat. This trial is registered at ClinicalTrials.gov, number NCT02515149. We enrolled 770 participants between July 1, 2013, and Feb 28, 2014. 692 (90%) had verified linkage to care status and 78 (10%) were lost to follow-up. Of 371 participants in the point-of-care group, 215 (58%) had linked to care within 6 months versus 108 (34%) of 321 in the standard-of-care group (Cox proportional multivariable hazard ratio [HR] 2·14, 95% CI 1·67-2·74; log rank pPoint-of-care CD4 cell counts in a resource-limited HBCT

  19. Reproducible Analysis and Blindness in a Null Test of Newton's Gravitational Inverse Square Law At Sub-millimeter Scales

    Science.gov (United States)

    Hagedorn, Charles; Venkateswara, Krishna; Gundlach, Jens

    2016-03-01

    Proper execution of an experiment is independent of its result. Physicists who test fundamental physical law face the reality that signals for new physics receive more attention and scrutiny than null results. Yet, null results may have greater impact upon the direction of both experiment and theory. Blind experiments and result-blind review are bulwarks against systematic human bias for both experimenters and referees. I'll describe the method that made possible an irreversible public unblinding of our torsion-balance parallel-plate test of gravity at submillimeter scales in 2015. One publicly-available computer procedure generated from blind raw data the analysis, the final result, and the complete documenting thesis. The experiment included an optical ``foil monitor'' to constrain a systematic effect intrinsic to all short-range parallel-plate gravity experiments. I'll describe the experiment, successes, lessons learned, and result. Supported by NSF (PHY-1305726) and DOE support for CENPA.

  20. Summary of the Blind Test Campaign to predict the High Reynolds number performance of DU00-W-210 airfoil

    DEFF Research Database (Denmark)

    Yilmaz, Özlem Ceyhan; Pires, Oscar; Munduate, Xabier

    2017-01-01

    This paper summarizes the results of a blind test campaign organized in the AVATAR project to predict the high Reynolds number performance of a wind turbine airfoil for wind turbine applications. The DU00-W-210 airfoil was tested in the DNW-HDG pressurized wind tunnel in order to investigate the ...

  1. Disturbance of visual functions as a result of temporary blinding from low power lasers

    Science.gov (United States)

    Reidenbach, Hans-Dieter

    2010-04-01

    Although it is well-known that dazzle, flash-blindness and afterimages may be caused by bright optical radiation, only sparse quantitative data are available with regard to the effects arising from low power laser products. Indirect effects like temporary blinding might result in serious incidents or even accidents due to the alteration of visual functions like visual acuity, contrast sensitivity and color discrimination. In order to determine the degree and duration of impairment resulting from dazzle, flash-blindness and afterimages, caused by a laser beam, an investigation has been performed with the goal to improve the current knowledge as far as especially the visual acuity recovery duration is concerned. Two different test set-ups were designed and applied in order to determine the afterimage duration and the recovery time for visual acuity after temporary blinding from a laser, respectively. In order to get the desired information a helium-neon laser was mounted on a movable assembly where the respective beam position and direction could be set up on a semicircle. In addition the mount could be inclined in a vertical plane in order to increase the variability of feasible settings. The power was adjusted in several steps in order to investigate the respective dependence of the afterimage. The investigations were relatively time consuming, since re-adaptation of about half an hour was necessary after every exposure in order not to falsify the results. The trials have been done with several volunteers in the laboratory. After the experimental mapping of the local afterimage duration for the various sites on the retina the foveal afterimage duration taf,fv produced by a red laser beam was determined. The investigations have shown a strong dependence on the angle between the line of sight and the beam direction. Besides a maximum of 300 s the dose relationship taf,fv/s ~ 50.6•ln[(P•texp)/μJ] - 13.4 for laser output powers P between 10 μW and 30 μW with

  2. EFTF cobalt test assembly results

    International Nuclear Information System (INIS)

    Rawlins, J.A.; Wootan, D.W.; Carter, L.L.; Brager, H.R.; Schenter, R.E.

    1988-01-01

    A cobalt test assembly containing yttrium hydride pins for neutron moderation was irradiated in the Fast Flux Test Facility during Cycle 9A for 137.7 equivalent full power days at a power level fo 291 MW. The 36 test pins consisted of a batch of 32 pins containing cobalt metal to produce Co-60, and a set of 4 pins with europium oxide to produce Gd-153, a radioisotope used in detection of the bone disease Osteoporosis. Post-irradiation examination of the cobalt pins determined the Co-60 produced with an accuracy of about 5 %. The measured Co-60 spatially distributed concentrations were within 20 % of the calculated concentrations. The assembly average Co-60 measured activity was 4 % less than the calculated value. The europium oxide pins were gamma scanned for the europium isotopes Eu-152 and Eu-154 to an absolute accuracy of about 10 %. The measured europium radioisotpe anc Gd-153 concentrations were within 20 % of calculated values. In conclusion, the hydride assembly performed well and is an excellent vehicle for many Fast Flux Test Facility isotope production applications. The results also demonstrate that the calculational methods developed by the Westinghouse Hanford Company are very accurate. (author)

  3. Evaluating the RELM Test Results

    Directory of Open Access Journals (Sweden)

    Michael K. Sachs

    2012-01-01

    Full Text Available We consider implications of the Regional Earthquake Likelihood Models (RELM test results with regard to earthquake forecasting. Prospective forecasts were solicited for M≥4.95 earthquakes in California during the period 2006–2010. During this period 31 earthquakes occurred in the test region with M≥4.95. We consider five forecasts that were submitted for the test. We compare the forecasts utilizing forecast verification methodology developed in the atmospheric sciences, specifically for tornadoes. We utilize a “skill score” based on the forecast scores λfi of occurrence of the test earthquakes. A perfect forecast would have λfi=1, and a random (no skill forecast would have λfi=2.86×10-3. The best forecasts (largest value of λfi for the 31 earthquakes had values of λfi=1.24×10-1 to λfi=5.49×10-3. The best mean forecast for all earthquakes was λ̅f=2.84×10-2. The best forecasts are about an order of magnitude better than random forecasts. We discuss the earthquakes, the forecasts, and alternative methods of evaluation of the performance of RELM forecasts. We also discuss the relative merits of alarm-based versus probability-based forecasts.

  4. EO framing flight test results

    Science.gov (United States)

    Lareau, Andre G.

    1995-09-01

    Recon/Optical, Inc. (ROI) has pioneered the electro-optical (E-O) framing generation of sensors with the CA-260, a KS-87 form/fit camera with a wafer-scale focal plane array (FPA) containing a patented, on-chip, forward motion compensation (FMC) architecture. The technology has now matured to the state where production E-O framing cameras are form/fit replacing their former film counterparts. During this interim production phase, flight demonstrations and tests are continuing to prove that E-O framing produces high-quality imagery, is robust to various platforms and mission tactics, interoperable with existing and planned C3I architectures, affordable and available, and meets the war-fighters needs. This paper discusses flight test results of the CA-260 E-O framing sensor flown in the F-14A TARPS during September 1994. This demonstration provided some unique imagery permitting a comparison of low-light level, in-flight FMC-on versus FMC-off performance. A first-level comparison of the resulting imagery based upon predicted FMC performance and post- processing numerical analysis is presented. The results indicae that the patented FMC architecture performed as predicted, and that for low-light conditions resulting in limited SNR images, on-chip FMC can provide a significant image quality improvement over post- processing alternatives.

  5. RSG Deployment Case Testing Results

    Energy Technology Data Exchange (ETDEWEB)

    Owsley, Stanley L.; Dodson, Michael G.; Hatchell, Brian K.; Seim, Thomas A.; Alexander, David L.; Hawthorne, Woodrow T.

    2005-09-01

    The RSG deployment case design is centered on taking the RSG system and producing a transport case that houses the RSG in a safe and controlled manner for transport. The transport case was driven by two conflicting constraints, first that the case be as light as possible, and second that it meet a stringent list of Military Specified requirements. The design team worked to extract every bit of weight from the design while striving to meet the rigorous Mil-Spec constraints. In the end compromises were made primarily on the specification side to control the overall weight of the transport case. This report outlines the case testing results.

  6. Cyclonic valve test: preliminary results

    Energy Technology Data Exchange (ETDEWEB)

    Monteiro, Andre Sampaio; Moraes, Carlos Alberto C.; Marins, Luiz Philipe M.; Soares, Fabricio; Oliveira, Dennis; Lima, Fabio Soares de; Airao, Vinicius [Petroleo Brasileiro S.A. (PETROBRAS), Rio de Janeiro, RJ (Brazil); Ton, Tijmen [Twister BV, Rijswijk (Netherlands)

    2012-07-01

    For many years, the petroleum industry has been developing a valve that input less shear to the flow for a given required pressure drop and this can be done using the cyclonic concept. This paper presents a comparison between the performances of a cyclonic valve (low shear) and a conventional globe valve. The aim of this work is to show the advantages of using a cyclonic low shear valve instead of the commonly used in the primary separation process by PETROBRAS. Tests were performed at PETROBRAS Experimental Center (NUEX) in Aracaju/SE varying some parameters: water cut; pressure loss (from 4 kgf/cm2 to 10 kgf/cm2); flow rates (30 m3/h and 45 m3/h). Results indicates a better performance of the cyclonic valve, if compared with a conventional one, and also that the difference of the performance, is a function of several parameters (emulsion stability, water content free, and oil properties). The cyclonic valve tested can be applied as a choke valve, as a valve between separation stages (for pressure drop), or for controlling the level of vessels. We must emphasize the importance to avoid the high shear imposed by conventional valves, because once the emulsion is created, it becomes more difficult to break it. New tests are being planned to occur in 2012, but PETROBRAS is also analyzing real cases where the applications could increase the primary process efficiency. In the same way, the future installations are also being designed considering the cyclonic valve usage. (author)

  7. ENRtool - BesTest results

    DEFF Research Database (Denmark)

    Wittchen, Kim Bjarne

    2007-01-01

    Test af beregninger gennemført med ENRtool over for BesTest valideringen under klimatiske forhold for Denver, Colorado.......Test af beregninger gennemført med ENRtool over for BesTest valideringen under klimatiske forhold for Denver, Colorado....

  8. FIRST RESULTS FROM OEDOTENSIOMETRIC TESTS

    Directory of Open Access Journals (Sweden)

    Luigi Cavazza

    2008-09-01

    Full Text Available An oedotensiometer was used to examine to examine the behaviour of sieved sample of a swelling soil (a vertisol as well as of the same soils treated with solution of Na+ + Ca2+ to simulate the soil changes from excessive irrigation with brackish water. The oedometer test consisted in an infiltration of water from below through a ceramic porous plate at a feeding pressure of +10 cm water and successive drainage under a depression mostly of -112 cm of water. The rate of water entry as well as the swelling rate of the sample were monitored. Preliminary considerations regards the domains in which the shrinkage curve of a swelling soil is subdivided and make hypothesis on the swelling process expected when the infiltration from below of the sample is applied. The results support the hypothesis that when the water pressure is applied some water enters rather rapidly in the larger structural pores and is followed later by the swelling in the smaller pores, responsible for the basic domain. This first conclusion demonstrates that the assumption of a simultaneous movement of solid and liquid components in the sample, which is the base of most theoretical developments for swelling soils, cannot be accepted for the tested samples. Some cases with water clogging on the sample surface confirm a late final swelling of the soil and permitted to evaluate the hydraulic conductivity of the swollen soil. These manifestations are more evident in sodicated soils. The loading of the sample reduces the swelling of the sample and seems to reduce its permeability. The reduction of the feeding water pressure further reduces the sample swelling. The draining process from saturated soil sample shows that most of the process occurs in the large pores of the structural domain. This gives the possibility to evaluate the water diffusivity coefficient for the structural domain of the sample. In draining the soil with the highest sodication there was a variation of soil volume

  9. Representing vision and blindness.

    Science.gov (United States)

    Ray, Patrick L; Cox, Alexander P; Jensen, Mark; Allen, Travis; Duncan, William; Diehl, Alexander D

    2016-01-01

    There have been relatively few attempts to represent vision or blindness ontologically. This is unsurprising as the related phenomena of sight and blindness are difficult to represent ontologically for a variety of reasons. Blindness has escaped ontological capture at least in part because: blindness or the employment of the term 'blindness' seems to vary from context to context, blindness can present in a myriad of types and degrees, and there is no precedent for representing complex phenomena such as blindness. We explore current attempts to represent vision or blindness, and show how these attempts fail at representing subtypes of blindness (viz., color blindness, flash blindness, and inattentional blindness). We examine the results found through a review of current attempts and identify where they have failed. By analyzing our test cases of different types of blindness along with the strengths and weaknesses of previous attempts, we have identified the general features of blindness and vision. We propose an ontological solution to represent vision and blindness, which capitalizes on resources afforded to one who utilizes the Basic Formal Ontology as an upper-level ontology. The solution we propose here involves specifying the trigger conditions of a disposition as well as the processes that realize that disposition. Once these are specified we can characterize vision as a function that is realized by certain (in this case) biological processes under a range of triggering conditions. When the range of conditions under which the processes can be realized are reduced beyond a certain threshold, we are able to say that blindness is present. We characterize vision as a function that is realized as a seeing process and blindness as a reduction in the conditions under which the sight function is realized. This solution is desirable because it leverages current features of a major upper-level ontology, accurately captures the phenomenon of blindness, and can be

  10. Diagnosis of carpal tunnel syndrome: interobserver reliability of the blinded scratch-collapse test

    NARCIS (Netherlands)

    Blok, Robin D.; Becker, Stéphanie J. E.; Ring, David C.

    2014-01-01

    The reliability of the scratch-collapse test for diagnosis of carpal tunnel syndrome (CTS) has not been tested by independent investigators. This study measured the reliability of the scratch-collapse test comparing the treating hand surgeon and blinded evaluators. We performed a prospective

  11. Testing advances in molecular discrimination among Chinook salmon life histories: evidence from a blind test.

    Science.gov (United States)

    Banks, Michael A; Jacobson, David P; Meusnier, Isabelle; Greig, Carolyn A; Rashbrook, Vanessa K; Ardren, William R; Smith, Christian T; Bernier-Latmani, Jeremiah; Van Sickle, John; O'Malley, Kathleen G

    2014-06-01

    The application of DNA-based markers toward the task of discriminating among alternate salmon runs has evolved in accordance with ongoing genomic developments and increasingly has enabled resolution of which genetic markers associate with important life-history differences. Accurate and efficient identification of the most likely origin for salmon encountered during ocean fisheries, or at salvage from fresh water diversion and monitoring facilities, has far-reaching consequences for improving measures for management, restoration and conservation. Near-real-time provision of high-resolution identity information enables prompt response to changes in encounter rates. We thus continue to develop new tools to provide the greatest statistical power for run identification. As a proof of concept for genetic identification improvements, we conducted simulation and blind tests for 623 known-origin Chinook salmon (Oncorhynchus tshawytscha) to compare and contrast the accuracy of different population sampling baselines and microsatellite loci panels. This test included 35 microsatellite loci (1266 alleles), some known to be associated with specific coding regions of functional significance, such as the circadian rhythm cryptochrome genes, and others not known to be associated with any functional importance. The identification of fall run with unprecedented accuracy was demonstrated. Overall, the top performing panel and baseline (HMSC21) were predicted to have a success rate of 98%, but the blind-test success rate was 84%. Findings for bias or non-bias are discussed to target primary areas for further research and resolution. © 2014 The Authors. Animal Genetics published by John Wiley & Sons Ltd on behalf of Stichting International Foundation for Animal Genetics.

  12. Chemical compatibility screening test results

    Energy Technology Data Exchange (ETDEWEB)

    Nigrey, P.J.; Dickens, T.G.

    1997-12-01

    A program for evaluating packaging components that may be used in transporting mixed-waste forms has been developed and the first phase has been completed. This effort involved the screening of ten plastic materials in four simulant mixed-waste types. These plastics were butadiene-acrylonitrile copolymer rubber, cross-linked polyethylene (XLPE), epichlorohydrin rubber, ethylene-propylene rubber (EPDM), fluorocarbon (Viton or Kel-F), polytetrafluoroethylene, high-density polyethylene (HDPE), isobutylene-isoprene copolymer rubber (butyl), polypropylene, and styrene-butadiene rubber (SBR). The selected simulant mixed wastes were (1) an aqueous alkaline mixture of sodium nitrate and sodium nitrite; (2) a chlorinated hydrocarbon mixture; (3) a simulant liquid scintillation fluid; and (4) a mixture of ketones. The testing protocol involved exposing the respective materials to 286,000 rads of gamma radiation followed by 14-day exposures to the waste types at 60{degrees}C. The seal materials were tested using vapor transport rate (VTR) measurements while the liner materials were tested using specific gravity as a metric. For these tests, a screening criterion of 0.9 g/hr/m{sup 2} for VTR and a specific gravity change of 10% was used. Based on this work, it was concluded that while all seal materials passed exposure to the aqueous simulant mixed waste, EPDM and SBR had the lowest VTRs. In the chlorinated hydrocarbon simulant mixed waste, only Viton passed the screening tests. In both the simulant scintillation fluid mixed waste and the ketone mixture simulant mixed waste, none of the seal materials met the screening criteria. For specific gravity testing of liner materials, the data showed that while all materials with the exception of polypropylene passed the screening criteria, Kel-F, HDPE, and XLPE offered the greatest resistance to the combination of radiation and chemicals.

  13. Chemical compatibility screening test results

    International Nuclear Information System (INIS)

    Nigrey, P.J.; Dickens, T.G.

    1997-12-01

    A program for evaluating packaging components that may be used in transporting mixed-waste forms has been developed and the first phase has been completed. This effort involved the screening of ten plastic materials in four simulant mixed-waste types. These plastics were butadiene-acrylonitrile copolymer rubber, cross-linked polyethylene (XLPE), epichlorohydrin rubber, ethylene-propylene rubber (EPDM), fluorocarbon (Viton or Kel-F), polytetrafluoroethylene, high-density polyethylene (HDPE), isobutylene-isoprene copolymer rubber (butyl), polypropylene, and styrene-butadiene rubber (SBR). The selected simulant mixed wastes were (1) an aqueous alkaline mixture of sodium nitrate and sodium nitrite; (2) a chlorinated hydrocarbon mixture; (3) a simulant liquid scintillation fluid; and (4) a mixture of ketones. The testing protocol involved exposing the respective materials to 286,000 rads of gamma radiation followed by 14-day exposures to the waste types at 60 degrees C. The seal materials were tested using vapor transport rate (VTR) measurements while the liner materials were tested using specific gravity as a metric. For these tests, a screening criterion of 0.9 g/hr/m 2 for VTR and a specific gravity change of 10% was used. Based on this work, it was concluded that while all seal materials passed exposure to the aqueous simulant mixed waste, EPDM and SBR had the lowest VTRs. In the chlorinated hydrocarbon simulant mixed waste, only Viton passed the screening tests. In both the simulant scintillation fluid mixed waste and the ketone mixture simulant mixed waste, none of the seal materials met the screening criteria. For specific gravity testing of liner materials, the data showed that while all materials with the exception of polypropylene passed the screening criteria, Kel-F, HDPE, and XLPE offered the greatest resistance to the combination of radiation and chemicals

  14. Report on the sixth blind test of organic crystal structure prediction methods.

    Science.gov (United States)

    Reilly, Anthony M; Cooper, Richard I; Adjiman, Claire S; Bhattacharya, Saswata; Boese, A Daniel; Brandenburg, Jan Gerit; Bygrave, Peter J; Bylsma, Rita; Campbell, Josh E; Car, Roberto; Case, David H; Chadha, Renu; Cole, Jason C; Cosburn, Katherine; Cuppen, Herma M; Curtis, Farren; Day, Graeme M; DiStasio, Robert A; Dzyabchenko, Alexander; van Eijck, Bouke P; Elking, Dennis M; van den Ende, Joost A; Facelli, Julio C; Ferraro, Marta B; Fusti-Molnar, Laszlo; Gatsiou, Christina Anna; Gee, Thomas S; de Gelder, René; Ghiringhelli, Luca M; Goto, Hitoshi; Grimme, Stefan; Guo, Rui; Hofmann, Detlef W M; Hoja, Johannes; Hylton, Rebecca K; Iuzzolino, Luca; Jankiewicz, Wojciech; de Jong, Daniël T; Kendrick, John; de Klerk, Niek J J; Ko, Hsin Yu; Kuleshova, Liudmila N; Li, Xiayue; Lohani, Sanjaya; Leusen, Frank J J; Lund, Albert M; Lv, Jian; Ma, Yanming; Marom, Noa; Masunov, Artëm E; McCabe, Patrick; McMahon, David P; Meekes, Hugo; Metz, Michael P; Misquitta, Alston J; Mohamed, Sharmarke; Monserrat, Bartomeu; Needs, Richard J; Neumann, Marcus A; Nyman, Jonas; Obata, Shigeaki; Oberhofer, Harald; Oganov, Artem R; Orendt, Anita M; Pagola, Gabriel I; Pantelides, Constantinos C; Pickard, Chris J; Podeszwa, Rafal; Price, Louise S; Price, Sarah L; Pulido, Angeles; Read, Murray G; Reuter, Karsten; Schneider, Elia; Schober, Christoph; Shields, Gregory P; Singh, Pawanpreet; Sugden, Isaac J; Szalewicz, Krzysztof; Taylor, Christopher R; Tkatchenko, Alexandre; Tuckerman, Mark E; Vacarro, Francesca; Vasileiadis, Manolis; Vazquez-Mayagoitia, Alvaro; Vogt, Leslie; Wang, Yanchao; Watson, Rona E; de Wijs, Gilles A; Yang, Jack; Zhu, Qiang; Groom, Colin R

    2016-08-01

    The sixth blind test of organic crystal structure prediction (CSP) methods has been held, with five target systems: a small nearly rigid molecule, a polymorphic former drug candidate, a chloride salt hydrate, a co-crystal and a bulky flexible molecule. This blind test has seen substantial growth in the number of participants, with the broad range of prediction methods giving a unique insight into the state of the art in the field. Significant progress has been seen in treating flexible molecules, usage of hierarchical approaches to ranking structures, the application of density-functional approximations, and the establishment of new workflows and `best practices' for performing CSP calculations. All of the targets, apart from a single potentially disordered Z' = 2 polymorph of the drug candidate, were predicted by at least one submission. Despite many remaining challenges, it is clear that CSP methods are becoming more applicable to a wider range of real systems, including salts, hydrates and larger flexible molecules. The results also highlight the potential for CSP calculations to complement and augment experimental studies of organic solid forms.

  15. Ultrasonic Transducer Irradiation Test Results

    Energy Technology Data Exchange (ETDEWEB)

    Daw, Joshua [Idaho National Lab. (INL), Idaho Falls, ID (United States); Palmer, Joe [Idaho National Lab. (INL), Idaho Falls, ID (United States); Ramuhalli, Pradeep [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Keller, Paul [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Montgomery, Robert [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Chien, Hual-Te [Argonne National Lab. (ANL), Argonne, IL (United States); Kohse, Gordon [MIT (Massachusetts Inst. of Technology), Cambridge, MA (United States); Tittmann, Bernhard [Pennsylvania State Univ., University Park, PA (United States); Reinhardt, Brian [Pennsylvania State Univ., University Park, PA (United States); Rempe, Joy [Rempe and Associates, Idaho Falls, ID (United States)

    2015-02-01

    Ultrasonic technologies offer the potential for high-accuracy and -resolution in-pile measurement of a range of parameters, including geometry changes, temperature, crack initiation and growth, gas pressure and composition, and microstructural changes. Many Department of Energy-Office of Nuclear Energy (DOE-NE) programs are exploring the use of ultrasonic technologies to provide enhanced sensors for in-pile instrumentation during irradiation testing. For example, the ability of small diameter ultrasonic thermometers (UTs) to provide a temperature profile in candidate metallic and oxide fuel would provide much needed data for validating new fuel performance models. Other ongoing efforts include an ultrasonic technique to detect morphology changes (such as crack initiation and growth) and acoustic techniques to evaluate fission gas composition and pressure. These efforts are limited by the lack of identified ultrasonic transducer materials capable of long term performance under irradiation test conditions. For this reason, the Pennsylvania State University (PSU) was awarded an ATR NSUF project to evaluate the performance of promising magnetostrictive and piezoelectric transducers in the Massachusetts Institute of Technology Research Reactor (MITR) up to a fast fluence of at least 1021 n/cm2. The goal of this research is to characterize and demonstrate magnetostrictive and piezoelectric transducer operation during irradiation, enabling the development of novel radiation-tolerant ultrasonic sensors for use in Material Testing Reactors (MTRs). As such, this test is an instrumented lead test and real-time transducer performance data is collected along with temperature and neutron and gamma flux data. The current work bridges the gap between proven out-of-pile ultrasonic techniques and in-pile deployment of ultrasonic sensors by acquiring the data necessary to demonstrate the performance of ultrasonic transducers. To date, one piezoelectric

  16. Railgun bore material test results

    International Nuclear Information System (INIS)

    Wang, S.Y.; Burton, R.L.; Witherspoon, F.D.; Bloomberg, H.W.; Goldstein, S.A.; Tidman, D.A.; Winsor, N.K.

    1987-01-01

    GT-Devices, Inc. has constructed a material test facility (MTF) to study the fundamental heat transfer problem of both railgun and electrothermal guns, and to test candidate gun materials under real plasma conditions. The MTF electrothermally produces gigawatt-level plasmas with pulse lengths of 10-30 microseconds. Circular bore and non-circular bore test barrels have been successfully operated under a wide range of simulated heating environments for EM launchers. Diagnostics include piezoelectric MHz pressure probes, time-of-flight probes, and current and voltage probes. Ablation measurements are accomplished by weighing and optical inspection, including borescope, optical microscope, and scanning electron microscope (SEM). From these measurements the ablation threshold for both the rail and insulator materials can be determined as a function of plasma heating. The MTF diagnostics are supported by an unsteady 1-D model of MTF which uses the flux-corrected transport (FCT) algorithm to calculate the fluid equations in conservative form. A major advantage of the FCT algorithm is that it can model gas dynamic shock behaviour without the requirement of numerical diffusion. The principle use of the code is to predict the material surface temperature ΔT/α from the unsteady heat transfer q(t)

  17. A Blind Test of the Younger Dryas Impact Hypothesis.

    Directory of Open Access Journals (Sweden)

    Vance Holliday

    Full Text Available The Younger Dryas Impact Hypothesis (YDIH states that North America was devastated by some sort of extraterrestrial event ~12,800 calendar years before present. Two fundamental questions persist in the debate over the YDIH: Can the results of analyses for purported impact indicators be reproduced? And are the indicators unique to the lower YD boundary (YDB, i.e., ~12.8k cal yrs BP? A test reported here presents the results of analyses that address these questions. Two different labs analyzed identical splits of samples collected at, above, and below the ~12.8ka zone at the Lubbock Lake archaeological site (LL in northwest Texas. Both labs reported similar variation in levels of magnetic micrograins (>300 mg/kg >12.8ka and <11.5ka, but <150 mg/kg 12.8ka to 11.5ka. Analysis for magnetic microspheres in one split, reported elsewhere, produced very low to nonexistent levels throughout the section. In the other split, reported here, the levels of magnetic microspherules and nanodiamonds are low or nonexistent at, below, and above the YDB with the notable exception of a sample <11,500 cal years old. In that sample the claimed impact proxies were recovered at abundances two to four orders of magnitude above that from the other samples. Reproducibility of at least some analyses are problematic. In particular, no standard criteria exist for identification of magnetic spheres. Moreover, the purported impact proxies are not unique to the YDB.

  18. Irradiation Effects Test Series: Test IE-2. Test results report

    International Nuclear Information System (INIS)

    Allison, C.M.; Croucher, D.W.; Ploger, S.A.; Mehner, A.S.

    1977-08-01

    The report describes the results of a test using four 0.97-m long PWR-type fuel rods with differences in diametral gap and cladding irradiation. The objective of this test was to provide information about the effects of these differences on fuel rod behavior during quasi-equilibrium and film boiling operation. The fuel rods were subjected to a series of preconditioning power cycles of less than 30 kW/m. Rod powers were then increased to 68 kW/m at a coolant mass flux of 4900 kg/s-m 2 . After one hour at 68 kW/m, a power-cooling-mismatch sequence was initiated by a flow reduction at constant power. At a flow of 2550 kg/s-m 2 , the onset of film boiling occurred on one rod, Rod IE-011. An additional flow reduction to 2245 kg/s-m 2 caused the onset of film boiling on the remaining three rods. Data are presented on the behavior of fuel rods during quasiequilibrium and during film boiling operation. The effects of initial gap size, cladding irradiation, rod power cycling, a rapid power increase, and sustained film boiling are discussed. These discussions are based on measured test data, preliminary postirradiation examination results, and comparisons of results with FRAP-T3 computer model calculations

  19. Sucralfate for radiation mucositis: results of a double-blind randomized trial

    International Nuclear Information System (INIS)

    Meredith, Ruby; Salter, Merle; Kim, Robert; Spencer, Sharon; Weppelmann, Burkhard; Rodu, Brad; Smith, Judy; Lee, Jeanette

    1997-01-01

    Purpose: To determine if addition of the ulcer-coating polysaccharide sucralfate could improve symptomatic relief of radiation mucositis over a popular combination of antacid, diphenhydramine, and viscous lidocaine alone. Methods and Materials: A double-blind study was conducted in which nurses and pharmacists coded patient groups and distributed medication in a manner blinded to both the patients and physicians. Eligible patients receiving radiation to the head and neck and/or chest sites that included the esophagus were randomized to a standard combination of antacid, diphenhydramine, and viscous lidocaine vs. the same solution plus sucralfate. Eligible patients were those receiving >40 Gy at 1.8 Gy/fraction, one fraction/day, five fractions/week. Participating patients were stratified between chest, small field head and neck, and large field head and neck. The observations and smears for Candidiasis screening. Medication was prescribed when the patient became symptomatic and concomitant use of other locally effective nonstudy agents was not allowed. The ability to eat various consistency of foods was graded 0-5, with 5 indicating no compromise of ability to ingest a food compared to baseline. Statistical analysis included mean + SD for food and soreness scores, paired t-test, and two-way analyses of variance to evaluate effects of site and treatment group on the changes in scores. Results: Over 2 years, 111 patients were entered. Because some withdrew and others did not require medication, results are presented for evaluable patients in each category. Mild adverse effects from the medication solution (usually mouth discomfort) were reported by <10% of patients in each treatment group among 106 patients evaluable for toxicity. There was a comparable incidence of mild-moderate mucositis for the two treatment groups. Severe mucositis was noted in two patients of the standard medication group and none among patients receiving sucralfate. The groups were comparable

  20. Abnormal Cervical Cancer Screening Test Results

    Science.gov (United States)

    ... lesion? • What are the different types of abnormal Pap test results? • What testing is needed after an abnormal ... that could lead to cancer. Screening includes the Pap test and, for some women, testing for a virus ...

  1. Testing the performance of a blind burst statistic

    Energy Technology Data Exchange (ETDEWEB)

    Vicere, A [Istituto di Fisica, Universita di Urbino (Italy); Calamai, G [Istituto Nazionale di Fisica Nucleare, Sez. Firenze/Urbino (Italy); Campagna, E [Istituto Nazionale di Fisica Nucleare, Sez. Firenze/Urbino (Italy); Conforto, G [Istituto di Fisica, Universita di Urbino (Italy); Cuoco, E [Istituto Nazionale di Fisica Nucleare, Sez. Firenze/Urbino (Italy); Dominici, P [Istituto di Fisica, Universita di Urbino (Italy); Fiori, I [Istituto di Fisica, Universita di Urbino (Italy); Guidi, G M [Istituto di Fisica, Universita di Urbino (Italy); Losurdo, G [Istituto Nazionale di Fisica Nucleare, Sez. Firenze/Urbino (Italy); Martelli, F [Istituto di Fisica, Universita di Urbino (Italy); Mazzoni, M [Istituto Nazionale di Fisica Nucleare, Sez. Firenze/Urbino (Italy); Perniola, B [Istituto di Fisica, Universita di Urbino (Italy); Stanga, R [Istituto Nazionale di Fisica Nucleare, Sez. Firenze/Urbino (Italy); Vetrano, F [Istituto di Fisica, Universita di Urbino (Italy)

    2003-09-07

    In this work, we estimate the performance of a method for the detection of burst events in the data produced by interferometric gravitational wave detectors. We compute the receiver operating characteristics in the specific case of a simulated noise having the spectral density expected for Virgo, using test signals taken from a library of possible waveforms emitted during the collapse of the core of type II supernovae.

  2. Rapid assessment of avoidable blindness in Uruguay: results of a nationwide survey

    Directory of Open Access Journals (Sweden)

    Marcelo Gallarreta

    2014-10-01

    Full Text Available OBJECTIVE: To investigate and describe the prevalence and causes of blindness and moderate and severe visual impairment in older adults living in Uruguay. METHODS: All individuals aged ≥ 50 years old living in randomly selected clusters were eligible to participate. In each census enumeration unit selected, 50 residents aged 50 years and older were chosen to participate in the study using compact segment sampling. The study participants underwent visual acuity (VA measurement and lens examination; those with presenting VA (PVA < 20/60 also underwent direct ophthalmoscopy. Moderate visual impairment (MVI was defined as PVA < 20/60-20/200, severe visual impairment (SVI was defined as PVA < 20/200-20/400, and blindness was defined as PVA < 20/400, all based on vision in the better eye with available correction. RESULTS: Out of 3 956 eligible individuals, 3 729 (94.3% were examined. The age- and sex-adjusted prevalence of blindness was 0.9% (95% confidence interval (CI: 0.5-1.3. Cataract (48.6% and glaucoma (14.3% were the main causes of blindness. Prevalence of SVI and MVI was 0.9% (95% CI: 0.5-1.3 and 7.9% (95% CI: 6.0-9.7 respectively. Cataract was the main cause of SVI (65.7%, followed by uncorrected refractive error (14.3%, which was the main cause of MVI (55.2%. Cataract surgical coverage was 76.8% (calculated by eye and 91.3% (calculated by individual. Of all eyes operated for cataract, 70.0% could see ≥ 20/60 and 15.3% could not see 20/200 post-surgery. CONCLUSIONS: Prevalence of blindness in Uruguay is low compared to other Latin American countries, but further reduction is feasible. Due to Uruguay's high cataract surgical coverage and growing proportion of people ≥ 50 years old, the impact of posterior pole diseases as a contributing factor to blindness might increase in future.

  3. Assessing Resilience in Students Who Are Deaf or Blind: Supplementing Standardized Achievement Testing

    Science.gov (United States)

    Butler, Michelle A.; Katayama, Andrew D.; Schindling, Casey; Dials, Katherine

    2018-01-01

    Although testing accommodations for standardized assessments are available for students with disabilities, interpretation remains challenging. The authors explored resilience to see if it could contribute to the interpretation of academic success for students who are deaf or hard of hearing or blind or have low vision. High school students (30…

  4. Estimating the accuracy of muscle response testing: two randomised-order blinded studies.

    Science.gov (United States)

    Jensen, Anne M; Stevens, Richard J; Burls, Amanda J

    2016-11-30

    Manual muscle testing (MMT) is a non-invasive assessment tool used by a variety of health care providers to evaluate neuromusculoskeletal integrity, and muscular strength in particular. In one form of MMT called muscle response testing (MRT), muscles are said to be tested, not to evaluate muscular strength, but neural control. One established, but insufficiently validated, application of MRT is to assess a patient's response to semantic stimuli (e.g. spoken lies) during a therapy session. Our primary aim was to estimate the accuracy of MRT to distinguish false from true spoken statements, in randomised and blinded experiments. A secondary aim was to compare MRT accuracy to the accuracy when practitioners used only their intuition to differentiate false from true spoken statements. Two prospective studies of diagnostic test accuracy using MRT to detect lies are presented. A true positive MRT test was one that resulted in a subjective weakening of the muscle following a lie, and a true negative was one that did not result in a subjective weakening of the muscle following a truth. Experiment 2 replicated Experiment 1 using a simplified methodology. In Experiment 1, 48 practitioners were paired with 48 MRT-naïve test patients, forming unique practitioner-test patient pairs. Practitioners were enrolled with any amount of MRT experience. In Experiment 2, 20 unique pairs were enrolled, with test patients being a mix of MRT-naïve and not-MRT-naïve. The primary index test was MRT. A secondary index test was also enacted in which the practitioners made intuitive guesses ("intuition"), without using MRT. The actual verity of the spoken statement was compared to the outcome of both index tests (MRT and Intuition) and their mean overall fractions correct were calculated and reported as mean accuracies. In Experiment 1, MRT accuracy, 0.659 (95% CI 0.623 - 0.695), was found to be significantly different (p Experiment 2 replicated the findings of Experiment 1. Testing for

  5. Opening a Side-Gate: Engaging the Excluded in Chilean Higher Education through Test-Blind Admission

    Science.gov (United States)

    Koljatic, Mladen; Silva, Monica

    2013-01-01

    The article describes a test-blind admission initiative in a Chilean research university aimed at expanding the inclusion of talented, albeit educationally and socially disadvantaged, students. The outcomes of the test-blind admission cohort were compared with those of students admitted via the regular admission procedure to the same academic…

  6. Sucralfate for radiation mucositis: results of a double-blind randomized trial

    International Nuclear Information System (INIS)

    Meredith, R.; Salter, M.; Kim, R.; Spencer, S.; Weppelmann, B.; Rodu, B.; Smith, J.; Lee, J.

    1995-01-01

    Purpose: To determine if addition of the ulcer-coating polysaccharide sucralfate could improve symptomatic relief of radiation mucositis over a popular combination of Maalox, diphenhyrdramine and viscous lidocaine alone. Methods: A double-blind study was conducted in which nurses/pharmacists coded patient groups and distributed medication in a manner blinded to both the patients and physicians. Eligible patients receiving radiation to the head and neck and/or chest sites that included the esophagus were randomized to a standard combination of Maalox, diphenhydramime and viscous lidocaine verses the same solution plus sucralfate. Eligible patients were those receiving > 40 Gy at 1.8 Gy/fraction, 1 fraction/day, 5 fractions/week. Participating patients were stratified between chest, small field head and neck, and large field head and neck. Baseline information regarding use of tobacco, alcohol, and food intake was obtained prior to symptomatic mucositis. This was compared with similar information obtained weekly once symptoms occurred. The patients subjected evaluation of throat soreness and relief with medication was elicited as well as physician observations and smears for Candidiasis screening. Medication was prescribed when the patient became symptomatic and concomitant use of other locally effective non-study agents was not allowed. Subjective soreness was graded on a scale of 0-20 with 0 indicating no soreness and 20 designating severe soreness that compromised ability to swallow secretions. The ability to eat various consistency of foods was graded 0-5 with 5 indicating no compromise of ability to ingest a food compared to baseline. Statistical analysis included mean + S.D. for food and soreness scores, paired t-test and two-way analyses of variance to evaluate effects of site and treatment group on the changes in scores. Results: Over 2 years, 110 patients were entered. Since some withdrew and others did not require medication, results are presented for

  7. 49 CFR 40.105 - What happens if the laboratory reports a result different from that expected for a blind specimen?

    Science.gov (United States)

    2010-10-01

    ... different from that expected for a blind specimen? 40.105 Section 40.105 Transportation Office of the... for a blind specimen? (a) If you are an employer, MRO, or C/TPA who submits a blind specimen, and if... expected results (obtained from the supplier of the blind specimen), and direct the laboratory to determine...

  8. Common Diagnostic Test Results Over the Years

    Directory of Open Access Journals (Sweden)

    Aruvee Eve

    2016-12-01

    Full Text Available In this article, common test results over the years 2000 – 2016 are analysed. The test questions for new entrants were based on secondary school mathematics. The students took the test in the first lesson of the higher mathematics course. The test results were analysed by years, by tasks and by specialities, and their differences were found. The test results’ dependence on state-exams score was studied and other types of dependence were looked at.

  9. General vs health specialized search engine: a blind comparative evaluation of top search results.

    Science.gov (United States)

    Pletneva, Natalia; Ruiz de Castaneda, Rafael; Baroz, Frederic; Boyer, Celia

    2014-01-01

    This paper presents the results of a blind comparison of top ten search results retrieved by Google.ch (French) and Khresmoi for everyone, a health specialized search engine. Participants--students of the Faculty of Medicine of the University of Geneva had to complete three tasks and select their preferred results. The majority of the participants have largely preferred Google results while Khresmoi results showed potential to compete in specific topics. The coverage of the results seems to be one of the reasons. The second being that participants do not know how to select quality and transparent health web pages. More awareness, tools and education about the matter is required for the students of Medicine to be able to efficiently distinguish trustworthy online health information.

  10. Making Sense of Residues on Flaked Stone Artefacts: Learning from Blind Tests

    Science.gov (United States)

    Rots, Veerle; Hayes, Elspeth; Cnuts, Dries; Lepers, Christian; Fullagar, Richard

    2016-01-01

    Residue analysis has become a frequently applied method for identifying prehistoric stone tool use. Residues adhering to the stone tool with varying frequencies are interpreted as being the result of an intentional contact with the worked material during use. Yet, other processes during the life cycle of a stone tool or after deposition may leave residues and these residues may potentially lead to misinterpretations. We present a blind test that was designed to examine this issue. Results confirm that production, retouch, prehension, hafting, various incidental contacts during use and deposition may lead to residue depositions that significantly affect the accurateness of identifications of tool-use. All currently applied residue approaches are concerned. We therefore argue for a closer interaction with independent wear studies and a step-wise procedure in which a low magnification of wear traces is used as a first step for selecting potentially used flakes in archaeological contexts. In addition, residue concentrations on a tool’s edge should be sufficiently dense before linking them with use. PMID:26930210

  11. Nests of red wood ants (Formica rufa-group) are positively associated with tectonic faults: a double-blind test.

    Science.gov (United States)

    Del Toro, Israel; Berberich, Gabriele M; Ribbons, Relena R; Berberich, Martin B; Sanders, Nathan J; Ellison, Aaron M

    2017-01-01

    Ecological studies often are subjected to unintentional biases, suggesting that improved research designs for hypothesis testing should be used. Double-blind ecological studies are rare but necessary to minimize sampling biases and omission errors, and improve the reliability of research. We used a double-blind design to evaluate associations between nests of red wood ants ( Formica rufa , RWA) and the distribution of tectonic faults. We randomly sampled two regions in western Denmark to map the spatial distribution of RWA nests. We then calculated nest proximity to the nearest active tectonic faults. Red wood ant nests were eight times more likely to be found within 60 m of known tectonic faults than were random points in the same region but without nests. This pattern paralleled the directionality of the fault system, with NNE-SSW faults having the strongest associations with RWA nests. The nest locations were collected without knowledge of the spatial distribution of active faults thus we are confident that the results are neither biased nor artefactual. This example highlights the benefits of double-blind designs in reducing sampling biases, testing controversial hypotheses, and increasing the reliability of the conclusions of research.

  12. Test results of HTTR control system

    International Nuclear Information System (INIS)

    Motegi, Toshihiro; Iigaki, Kazuhiko; Saito, Kenji; Sawahata, Hiroaki; Hirato, Yoji; Kondo, Makoto; Shibutani, Hideki; Ogawa, Satoru; Shinozaki, Masayuki; Mizushima, Toshihiko; Kawasaki, Kozo

    2006-06-01

    The plant control performance of the IHX helium flow rate control system, the PPWC helium flow rate control system, the secondary helium flow rate control system, the inlet temperature control system, the reactor power control system and the outlet temperature control system of the HTTR are obtained through function tests and power-up tests. As the test results, the control systems show stable control response under transient condition. Both of inlet temperature control system and reactor power control system shows stable operation from 30% to 100%, respectively. This report describes the outline of control systems and test results. (author)

  13. SULTAN test facility: Summary of recent results

    International Nuclear Information System (INIS)

    Stepanov, Boris; Bruzzone, Pierluigi; Sedlak, Kamil; Croari, Giancarlo

    2013-01-01

    The test campaigns of the ITER conductors in the SULTAN test facility re-started in December 2011 after three months break. The main focus of the activities is about the qualification tests of the Central Solenoid (CS) conductors, with three different samples for a total six variations of strand suppliers and cable layouts. In 2012, five Toroidal Field (TF) conductor samples have also been tested as part of the supplier and process qualification phase of the European, Korean, Chinese and Russian Federation Agencies. A summary of the test results for all the ITER samples tested in the last period is presented, including an updated statistics of the broad transition, the performance degradation and the impact of layout variations. The role of SULTAN test facility during the ITER construction is reviewed, and the load of work for the next three years is anticipated

  14. The Gluten-Free, Casein-Free Diet in Autism: Results of a Preliminary Double Blind Clinical Trial

    Science.gov (United States)

    Elder, Jennifer Harrison; Shankar, Meena; Shuster, Jonathan; Theriaque, Douglas; Burns, Sylvia; Sherrill, Lindsay

    2006-01-01

    This study tested the efficacy of a gluten-free and casein-free (GFCF) diet in treating autism using a randomized, double blind repeated measures crossover design. The sample included 15 children aged 2-16 years with autism spectrum disorder. Data on autistic symptoms and urinary peptide levels were collected in the subjects' homes over the 12…

  15. Characteristics of Programs for Children with Deaf-Blindness: Results of a National Survey.

    Science.gov (United States)

    Bullis, Michael; Otos, Maurine

    1988-01-01

    A national survey of state coordinators of specialized service programs for children with deaf-blindness examined program characteristics including administrative structure, teacher certification requirements, technical assistance, eligibility determination, educational placement, curricula/instructional settings, transition, and unmet educational…

  16. NEXT Single String Integration Test Results

    Science.gov (United States)

    Soulas, George C.; Patterson, Michael J.; Pinero, Luis; Herman, Daniel A.; Snyder, Steven John

    2010-01-01

    As a critical part of NASA's Evolutionary Xenon Thruster (NEXT) test validation process, a single string integration test was performed on the NEXT ion propulsion system. The objectives of this test were to verify that an integrated system of major NEXT ion propulsion system elements meets project requirements, to demonstrate that the integrated system is functional across the entire power processor and xenon propellant management system input ranges, and to demonstrate to potential users that the NEXT propulsion system is ready for transition to flight. Propulsion system elements included in this system integration test were an engineering model ion thruster, an engineering model propellant management system, an engineering model power processor unit, and a digital control interface unit simulator that acted as a test console. Project requirements that were verified during this system integration test included individual element requirements ; integrated system requirements, and fault handling. This paper will present the results of these tests, which include: integrated ion propulsion system demonstrations of performance, functionality and fault handling; a thruster re-performance acceptance test to establish baseline performance: a risk-reduction PMS-thruster integration test: and propellant management system calibration checks.

  17. Olsalazine is contraindicated during pelvic radiation therapy: results of a double-blind, randomized clinical trial

    International Nuclear Information System (INIS)

    Martenson, James A.; Hyland, Glenn; Moertel, Charles G.; Mailliard, James A.; O'Fallon, Judith R.; Collins, Roger T.; Morton, Roscoe F.; Tewfik, Hamed H.; Moore, Randy L.; Frank, Albert R.; Urias, Rodolfo E.; Deming, Richard L.

    1996-01-01

    Purpose: A randomized clinical trial from Great Britain suggested a possible beneficial effect of acetylsalicylate in the prevention of radiation-induced bowel toxicity. Olsalazine is an orally administered drug designed to deliver 5-aminosalicylate to the large bowel with minimal systemic absorption. A randomized clinical trial was undertaken to assess the effectiveness of olsalazine in preventing acute diarrhea in patients receiving pelvic radiation therapy. Methods and Materials: Patients receiving pelvic radiation therapy were randomized, in double-blind fashion, to olsalazine 250 mg, two capsules twice daily, or an identical appearing placebo, two capsules twice daily. Patients were then evaluated weekly during radiation therapy for the primary study endpoint, diarrhea, as well as rectal bleeding, abdominal cramping, and tenesmus. Results: The study was closed early, after entry of 58 evaluable patients, when a preliminary analysis showed excessive diarrhea in patients randomized to olsalazine. The incidence and severity of diarrhea were worse in patients randomized to olsalazine (p 0.0036). Sixty percent of the patients randomized to olsalazine experienced Grade 3 or 4 diarrhea compared to only 14% randomized to placebo. There was also a trend toward higher incidence and greater severity of abdominal cramping in patients who were randomized to olsalazine (p = 0.084). Conclusion: Administration of olsalazine during pelvic radiation therapy resulted in an increased incidence and severity of diarrhea. Olsalazine is contraindicated in patients receiving pelvic radiation therapy

  18. Initial Burn Pan (JMTF) Testing Results

    Science.gov (United States)

    2016-03-01

    Accession Number 3. Recipient’s Catalog No. 4. Title and Subtitle Initial Burn Pan (JMTF) Testing Results 5. Report Date March 2016 6...trough is filled with water to provide cooling of the fire pan walls. Figure 4 shows the interior of the refurbished burn pan. There are a number of...first test (static burn of 378 liters (100 gallons) of diesel), was used to calculate the fuel regression based on the fuel depth prior to the fire and

  19. Acknowledging the results of blood tests

    DEFF Research Database (Denmark)

    Torkilsheyggi, Arnvør Martinsdottir á; Hertzum, Morten

    At the studied hospital, physicians from the Medical and Surgical Departments work some of their shifts in the Emergency Department (ED). Though icons showing the blood-test process were introduced on electronic whiteboards in the ED, these icons did not lead to increased attention to test...... acknowledgement. Rather, the physicians, trans-ferred work practices from their own departments, which did not have electronic white-boards, to the ED. This finding suggests a challenge to the cross-disciplinary work and norms for how to follow up on blood-test results in the ED....

  20. Prospective, randomized, open-label, blinded-endpoint (PROBE) designed trials yield the same results as double-blind, placebo-controlled trials with respect to ABPM measurements.

    Science.gov (United States)

    Smith, David H; Neutel, Joel M; Lacourcière, Yves; Kempthorne-Rawson, Joan

    2003-07-01

    This meta-analysis aimed to determine whether ambulatory blood pressure monitoring (ABPM) results from double-blind, placebo-controlled (DBPC) and prospective, randomized, open-label, blinded-endpoint (PROBE) hypertension trials are statistically comparable. Two DBPC and three PROBE parallel-group studies were selected from an angiotensin II receptor blocker clinical programme. These were fixed-dose studies involving similar mild to moderate hypertensive patient populations. All used SpaceLabs 90207 ABPM devices, and each comprised a 4-week placebo period and a 4-8-week treatment period. Data from patients receiving telmisartan 80 mg were used to compare the results of DBPC (126 patients) and PROBE (734 patients) trials. The analysis had approximately 87% power to show equivalence between the two design types in terms of ruling out differences of >or= 3 mmHg in SBP and >or= 2 mmHg in DBP. Office blood pressure was also compared. The change from baseline in mean 24-h ambulatory SBP was -12.2 mmHg in DBPC trials and -12.3 mmHg in PROBE trials, a rounded difference of 0.2 mmHg [95% confidence interval (CI): -1.8, 2.1]. The change from baseline in mean 24-h ambulatory DBP was -7.7 mmHg in DBPC trials versus -7.9 mmHg in PROBE trials, a difference of 0.2 mmHg (95% CI: -1.1, 1.5). Ambulatory pulse pressure results were identical. Thus, changes in mean 24-h ambulatory blood pressure from the DBPC and PROBE trials in this meta-analysis are statistically equivalent in terms of ruling out a difference of >or= 3 mmHg in SBP and >or= 2 mmHg in DBP. This supports the validity of the PROBE design in assessing antihypertensive efficacy based on blinded ABPM measurements.

  1. Purse-string suture vs second intention healing: results of a randomized, blind clinical trial.

    Science.gov (United States)

    Joo, Jayne; Custis, Trenton; Armstrong, April W; King, Thomas H; Omlin, Kenny; Kappel, Stefani T; Eisen, Daniel B

    2015-03-01

    Purse-string suture is a closure method that purportedly reduces the scar area compared with second intention healing. Randomized clinical trials comparing these 2 methods appear to be limited or absent. To determine if purse-string suture improves cosmetic outcome, healing time, and scar to defect area compared with second intention healing for circular defects on the trunk and extremities. Prospective, 2-arm, randomized, evaluator-blinded clinical trial in a single-center outpatient academic dermatology center. Patients were eligible if they were older than 18 years, able to give informed consent, and had circular or oval postoperative defects larger than 8 mm on the trunk or extremities. For the purse-string treatment arm, wounds were sewn in circumferential fashion using polydiaxanone suture. Patients in the other treatment arm were allowed to heal by second intent. The primary outcome measures were the mean total Patient and Observer Scar Assessment Scale (POSAS) scores ascertained from the patient and 2 blinded observers. Secondary outcomes included the ratio of scar to initial defect size, healing time, pain scores, and complication rates. Fifty-two patients were screened, and a total of 44 patients with 50 surgical sites were enrolled. Forty-two patients with 48 surgical sites completed the study. The mean total observer POSAS score was 18.38 for the purse-string group vs 19.91 for the secondary intention group, a nonsignificant difference (P = .41). Similarly, there were no significant differences for any of the following secondary outcome measures: mean total patient POSAS score (P = .96), mean scar-to-defect area (P = .61), and mean pain level at week 1 (P = .19). Statistical trends toward significance were seen in the mean healing time in favor of purse-string suture (P = .10) and scar relief, which favored second intention healing (P = .07). The purse-string suture results in similar cosmetic outcomes, scar sizes, and pain

  2. First results of the CINDI-2 semi-blind MAX-DOAS intercomparison

    Science.gov (United States)

    Kreher, Karin; van Roozendael, Michel; Hendrick, Francois; Apituley, Arnoud; Friess, Udo; Lampel, Johannes; Piters, Ankie; Richter, Andreas; Wagner, Thomas; Cindi-2 Participants, All

    2017-04-01

    The second Cabauw Intercomparison campaign for Nitrogen Dioxide measuring Instruments (CINDI-2) took place at the Cabauw Experimental Site for Atmospheric Research (CESAR; Utrecht area, The Netherlands) from 25 August until 7 October 2016. The goals of this inter-comparison campaign are to support the creation of high-quality ground-based data sets (e.g. to provide reliable long-term time series for trend analysis and satellite data validation), to characterise and better understand the differences between a large number of MAX-DOAS and DOAS instruments and analysis methods, and to contribute to a harmonisation of the measurement settings and retrieval methods. During a time period of 17 days, from 12 to 28 September 2016, a formal semi-blind intercomparison was held following a detailed measurement protocol. The development of this protocol was based on the experience gained during the first CINDI campaign held in 2009 as well as more recent projects and campaigns such as the MADCAT campaign in Mainz, Germany, in 2013. Strong emphasis was put on the careful synchronisation of the measurement sequence and on exact alignment of the elevation angles using horizon scans and lamp measurements. In this presentation, we provide an overview and some highlights of the MAX-DOAS semi-blind intercomparison campaign. We will introduce the participating groups, their instruments and the measurement protocol details, and then summarize the campaign outcomes to date. The CINDI-2 data sets have been investigated using a range of diagnostics including comparisons of daily time series and relative differences between the data sets, regression analysis and correlation plots. The data products so far investigated are NO2 (nitrogen dioxide) in the UV and visible wavelength region, O4 (oxygen dimer) in the same two wavelength intervals, O3 (ozone) in the UV and visible wavelength region, HCHO (formaldehyde) and NO2 in an additional (smaller) wavelength range in the visible. The results

  3. Results of interlaboratory tests regarding TXRF

    International Nuclear Information System (INIS)

    Klockenkaemper, R.; Bohlen, A. von

    2000-01-01

    Interlaboratory or intercomparison tests can be performed for proficiency testing of individual laboratories, for the certification of a special sample material and for the validation of a certain method. We participated in two interlaboratory tests in order to validate total reflection x-ray fluorescence analysis (TXRF). We used our results to evaluate TXRF and to compare it with other competing methods, particularly with respect of precision and accuracy. The first interlaboratory test was organized by IAEA (International Atomic Energy Agency, Vienna, Austria). As a candidate for reference material, a lichen (IAEA-336 Lichen) was distributed among 27 participants. In our laboratory, the powdered biogenic material was digested with nitric acid under high pressure and analyzed by TXRF. - The second interlaboratory test was organized by IRMM (Institute for Reference Materials and Measurements, Geel, Belgium). As a certified test sample with undisclosed values, a sediment (IMEP-14) was delivered to 220 laboratories. We digested the geogenic material again by nitric acid and additionally by hydrofluoric acid and analyzed it by TXRF. - In both test samples, six or eight different trace elements, respectively, were determined by TXRF with a content between 2 and 2000 mg/kg. Calibration was carried out by internal standardization. For that purpose, Ga or Se, respectively, was added as standard element. The measurement uncertainty of TXRF was estimated by the method of error propagation. In our paper we will report on the results of the two interlaboratory tests. It will be shown that TXRF is highly reliable for a correct determination of trace elements in biogenic and geogenic samples. It is competitive with the established methods of trace analyses which were involved in these tests and it is even superior to them in certain aspects. (author)

  4. BPX insulation irradiation program test results

    International Nuclear Information System (INIS)

    McManamy, T.J.; Kanemoto, G.; Snook, P.G.

    1991-01-01

    The toroidal field coil insulation for the Burning Plasma Experiment (BPX) is expected to receive a radiation dose of nearly 10 10 rad and to withstand significant mechanical stresses. An irradiation test program was performed at the Idaho National Engineering Laboratory (INEL) using the Advanced Technology Reactor (ATR) for irradiations to doses on the order of 3 x 10 10 rad. The flexure and shear strength with compression of commercially procured sheet material were reported earlier. A second series of tests has been performed to slightly higher dose levels with vacuum impregnated materials, glass strand material, and Spaulrad-S sheet samples. Vacuum impregnation with a Shell 9405 resin and 9470 hardener was used to produce bonded copper squares and flexure samples of both pure resin and resin with S-glass. A new test fixture was developed to test the bonded samples in shear without applied compression. The Spaulrad-S flexure samples demonstrated a loss of strength with irradiation, similar to previous results. The pure resin lost nearly all flexibility, while the S-glass-reinforced samples retained between 30% and 40% of the initial flexure strength. The S-glass strands showed a 30% loss of strength at the higher dose level when tested in tension. The bonded copper squares had a low room-temperature shear strength of approximately 17 MPa before irradiation, which was unchanged in the irradiated samples. Shear testing of unirradiated bonded copper squares with ten different types of surface treatment revealed that the low shear strength resulted from the polyurethane primer used. In the later series of test, the epoxy-based primers and DZ-80 from Ciba-Geigy did much better, with shear strengths on the order of 40 MPa. These samples also demonstrated a resistance to cryogenic shock. One irradiated bonded sample was tested up 10 210 MPa in compression, the limit of the test fixture, without failure

  5. Test Results of PBMR Fuel Spheres

    International Nuclear Information System (INIS)

    Koshcheev, Konstantin; Diakov, Alexander; Beltyukov, Igor; Barybin, Andrey; Chernetsov, Mikhail

    2014-01-01

    Results of pre-irradiation testing of fuel spheres (FS) and coated particles (CP) manufactured by PBMR SOC (Republic of South Africa) are described. The stable high quality level of major characteristics (dimensions, CP coating structure, uranium-235 contamination of the FS matrix graphite and the outer PyC layer of the CP coating) are shown. Results of a methodical irradiation test of two FS in helium and neon medium at temperatures of 800 to 1300 °C with simultaneous determination of release-to-birth ratios for major gaseous fission products (GFP) are described. (author)

  6. Blind tests of methods for InSight Mars mission: Open scientific challenge

    Science.gov (United States)

    Clinton, John; Ceylan, Savas; Giardini, Domenico; Khan, Amir; van Driel, Martin; Böse, Maren; Euchner, Fabian; Garcia, Raphael F.; Drilleau, Mélanie; Lognonné, Philippe; Panning, Mark; Banerdt, Bruce

    2017-04-01

    The Marsquake Service (MQS) will be the ground segment service within the InSight mission to Mars, which will deploy a single seismic station on Elysium Planitia in November 2018. The main tasks of the MQS are the identification and characterisation of seismicity, and managing the Martian seismic event catalogue. In advance of the mission, we have developed a series of single station event location methods that rely on a priori 1D and 3D structural models. In coordination with the Mars Structural Service, we expect to use iterative inversion techniques to revise these structural models and event locations. In order to seek methodological advancements and test our current approaches, we have designed a blind test case using Martian synthetics combined with realistic noise models for the Martian surface. We invite all scientific parties that are interested in single station approaches and in exploring the Martian time-series to participate and contribute to our blind test. We anticipate the test will can improve currently developed location and structural inversion techniques, and also allow us explore new single station techniques for moment tensor and magnitude determination. The waveforms for our test case are computed employing AxiSEM and Instaseis for a randomly selected 1D background model and event catalogue that is statistically consistent with our current expectation of Martian seismicity. Realistic seismic surface noise is superimposed to generate a continuous time-series spanning 6 months. The event catalog includes impacts as well as Martian quakes. The temporal distribution of the seismicity in the timeseries, as well as the true structural model, are not be known to any participating parties including MQS till the end of competition. We provide our internal tools such as event location codes, suite of background models, seismic phase travel times, in order to support researchers who are willing to use/improve our current methods. Following the deadline

  7. The Pakistan national blindness and visual impairment survey--research design, eye examination methodology and results of the pilot study.

    Science.gov (United States)

    Bourne, Rupert; Dineen, Brendan; Jadoon, Zahid; Lee, Pak S; Khan, Aman; Johnson, Gordon J; Foster, Allen; Khan, Daud

    2005-10-01

    To establish age- and sex-specific prevalence rates and causes of blindness and low vision in children aged 10 to 15 years and adults aged 30 years and older in Pakistan. Multi-stage, stratified (rural/urban), cluster random sampling, with probability proportional-to-size procedures, was utilised to select a cross-sectional, nationally representative sample of adults (16,600 subjects) and children (6,000 subjects). Each subject underwent: interview, visual acuity (logMAR), autorefraction and optic disc examination. Those that saw visual acuity and dilated posterior segment examination. The results of a pilot survey are reported in this paper. In the two rural pilot sites, 159 subjects (including 47 children) were examined; 50% were male. Thirty seven adults (23.3%) but no children saw worse than 6/12 in either eye. Two subjects were blind (corrected visual acuity) in the better eye, and 11 were visually impaired. Refractive error was the main cause (in 22 eyes (39% of the total of 56 eyes)) of visual acuity, followed by cataract (12 eyes), uncorrected aphakia (6 eyes) and age-related macular disease (3 eyes). The pilot survey demonstrated that the proposed examination process for the main survey is feasible. Particular strengths of this survey include the use of logMAR visual acuity testing and autorefraction of all subjects, a dilated posterior segment examination, and the use of a 'less than 6/12' threshold for further examination. This lower threshold addresses the burden of refractive error, which, with cataract, are two of the diseases specifically targeted by Vision 2020.

  8. Mavoglurant in fragile X syndrome: Results of two randomized, double-blind, placebo-controlled trials.

    Science.gov (United States)

    Berry-Kravis, Elizabeth; Des Portes, Vincent; Hagerman, Randi; Jacquemont, Sébastien; Charles, Perrine; Visootsak, Jeannie; Brinkman, Marc; Rerat, Karin; Koumaras, Barbara; Zhu, Liansheng; Barth, Gottfried Maria; Jaecklin, Thomas; Apostol, George; von Raison, Florian

    2016-01-13

    Fragile X syndrome (FXS), the most common cause of inherited intellectual disability and autistic spectrum disorder, is typically caused by transcriptional silencing of the X-linked FMR1 gene. Work in animal models has described altered synaptic plasticity, a result of the up-regulation of metabotropic glutamate receptor 5 (mGluR5)-mediated signaling, as a putative downstream effect. Post hoc analysis of a randomized, placebo-controlled, crossover phase 2 trial suggested that the selective mGluR5 antagonist mavoglurant improved behavioral symptoms in FXS patients with completely methylated FMR1 genes. We present the results of two phase 2b, multicenter, randomized, double-blind, placebo-controlled, parallel-group studies of mavoglurant in FXS, designed to confirm this result in adults (n = 175, aged 18 to 45 years) and adolescents (n = 139, aged 12 to 17 years). In both trials, participants were stratified by methylation status and randomized to receive mavoglurant (25, 50, or 100 mg twice daily) or placebo over 12 weeks. Neither of the studies achieved the primary efficacy end point of improvement on behavioral symptoms measured by the Aberrant Behavior Checklist-Community Edition using the FXS-specific algorithm (ABC-C(FX)) after 12 weeks of treatment with mavoglurant. The safety and tolerability profile of mavoglurant was as previously described, with few adverse events. Therefore, under the conditions of our study, we could not confirm the mGluR theory of FXS nor the ability of the methylation state of the FMR1 promoter to predict mavoglurant efficacy. Preclinical results suggest that future clinical trials might profitably explore initiating treatment in a younger population with longer treatment duration and longer placebo run-ins and identifying new markers to better assess behavioral and cognitive benefits. Copyright © 2016, American Association for the Advancement of Science.

  9. Cone Penetrometer N Factor Determination Testing Results

    Energy Technology Data Exchange (ETDEWEB)

    Follett, Jordan R.

    2014-03-05

    This document contains the results of testing activities to determine the empirical 'N Factor' for the cone penetrometer in kaolin clay simulant. The N Factor is used to releate resistance measurements taken with the cone penetrometer to shear strength.

  10. Influence of Age on Patch Tests Results

    Directory of Open Access Journals (Sweden)

    Aouatef Mahfoudh

    2017-03-01

    Full Text Available Objective: To assess the influence of age on the patch-test results and to compare the profiles of skin sensitizers according to the age groups. Methods: It is an 8-year retrospective study involving entire medical records of the patients with allergic contact dermatitis at the Unity of Dermatology and Allergology in the Department of Occupational Medicine, University Hospital of Sousse in Tunisia. Study population was divided into two age groups (group 1: patients 40 years. The statistical significance level was taken as p<0.05. Results: Among the patients, 586 have had at least one positive reaction to the patch-test. Older individuals were 1.1 times more likely to have at least one positive reaction to the patch-test than younger ones. The most common allergens in both groups are potassium dichromate (34.2% vs. 38%, thiuram mix (6% vs. 11%, cobalt chloride (27% vs. 28.8%, balsam of Peru (6% vs. 11.3% and nickel sulphate (41% vs. 27.3%. A significant variation was noted for potassium dichromate in terms of intensity of skin reaction (p=0.00. Conclusion: More research is needed to elucidate the physiologic mechanisms of age on the patch-test results and to adapt the European Standard Battery to each age group in term of allergen type and their appropriate concentration.

  11. A 20-week program of resistance or concurrent exercise improves symptoms of schizophrenia: results of a blind, randomized controlled trial

    Directory of Open Access Journals (Sweden)

    Bruna Andrade e Silva

    2015-01-01

    Full Text Available Objective:To evaluate the effects of 20 weeks of resistance and concurrent training on psychotic and depressive symptoms, quality of life outcomes, and serum IGF-1, IGFBP-3, and brain-derived neurotrophic factor (BDNF concentrations in patients with schizophrenia.Methods:In this blind, randomized controlled clinical trial, 34 patients with schizophrenia were assigned to one of three groups: control (CTRL, n=13, resistance exercise (RESEX, n=12, or concurrent exercise (CONCEX, n=9. Symptoms, quality of life, strength, and other variables were assessed.Results:A significant time-by-group interaction was found for the RESEX and CONCEX groups on the Positive and Negative Syndrome Scale (PANSS total score for disease symptoms (p = 0.007, positive symptoms (p = 0.003, and on the arm extension one-repetition maximum (1RM test (p = 0.016. In addition, significant improvements on negative symptoms (p = 0.027, on the role-physical domain of the Short Form-36 Health Survey (p = 0.019, and on the chest press 1RM test (p = 0.040 were observed in the RESEX group. No changes were observed for the other variables investigated.Conclusions:In this sample of patients with schizophrenia, 20 weeks of resistance or concurrent exercise program improved disease symptoms, strength, and quality of life. ClinicalTrials.gov: NCT01674543.

  12. Field Cone Penetration Tests with Various Penetration Rates - Test Results

    DEFF Research Database (Denmark)

    Poulsen, Rikke; Nielsen, Benjaminn Nordahl; Ibsen, Lars Bo

    was encountered at approximately 0.2-0.6 m below the ground level. The soil stratigraphy of the test site was before test start identified by geotechnical borings results. The geotechnical borings indicated that the site contains of sandy silt with clay stripes from approx. 4.0 to 10 m. In the top the silty soil...... is very sandy with few clay stripes, and gradually the clay stripes increases wherefore the soil from approx. 10 m contains of clay with sandy silt stripes. Large soil sample was also collected from the test site in order to determine basic soil properties in the laboratory.......The test site is located at Nordre Ringgade near the town called Dronninglund in the northern Jutland in Denmark. The site area is relatively flat, and was chosen because it has a size of approximately 3 ha and contains a relatively thick deposit of silty soils. Furthermore the groundwater...

  13. Identification of hazelnut major allergens in sensitive patients with positive double-blind, placebo-controlled food challenge results

    DEFF Research Database (Denmark)

    Pastorello, Elide A; Vieths, Stefan; Pravettoni, Valerio

    2002-01-01

    The hazelnut major allergens identified to date are an 18-kd protein homologous to Bet v 1 and a 14-kd allergen homologous to Bet v 2. No studies have reported hazelnut allergens recognized in patients with positive double-blind, placebo-controlled food challenge (DBPCFC) results or in patients...

  14. CLSM bleed water reduction test results

    International Nuclear Information System (INIS)

    Langton, C.A.; Rajendran, N.

    1997-01-01

    Previous testing by BSRI/SRTC/Raytheon indicated that the CLSM specified for the Tank 20 closure generates about 6 gallons (23 liters) of bleed water per cubic yard of material (0.76 m3).1 This amount to about 10 percent of the total mixing water. HLWE requested that the CLSM mix be optimized to reduce bleed water while maintaining flow. Elimination of bleed water from the CLSM mix specified for High-Level Waste Tank Closure will result in waste minimization, time savings and cost savings. Over thirty mixes were formulated and evaluated at the on-site Raytheon Test Laboratory. Improved low bleed water CLSM mixes were identified. Results are documented in this report

  15. Rapid assessment of avoidable blindness in Uruguay: results of a nationwide survey.

    Science.gov (United States)

    Gallarreta, Marcelo; Furtado, João M; Lansingh, Van C; Silva, Juan Carlos; Limburg, Hans

    2014-10-01

    To investigate and describe the prevalence and causes of blindness and moderate and severe visual impairment in older adults living in Uruguay. All individuals aged ≥ 50 years old living in randomly selected clusters were eligible to participate. In each census enumeration unit selected, 50 residents aged 50 years and older were chosen to participate in the study using compact segment sampling. The study participants underwent visual acuity (VA) measurement and lens examination; those with presenting VA (PVA) glaucoma (14.3%) were the main causes of blindness. Prevalence of SVI and MVI was 0.9% (95% CI: 0.5-1.3) and 7.9% (95% CI: 6.0-9.7) respectively. Cataract was the main cause of SVI (65.7%), followed by uncorrected refractive error (14.3%), which was the main cause of MVI (55.2%). Cataract surgical coverage was 76.8% (calculated by eye) and 91.3% (calculated by individual). Of all eyes operated for cataract, 70.0% could see ≥ 20/60 and 15.3% could not see 20/200 post-surgery. Prevalence of blindness in Uruguay is low compared to other Latin American countries, but further reduction is feasible. Due to Uruguay's high cataract surgical coverage and growing proportion of people ≥ 50 years old, the impact of posterior pole diseases as a contributing factor to blindness might increase in future.

  16. Use of the Blind Learning Aptitude Test with Children in England and Wales and the United States.

    Science.gov (United States)

    Mason, H. L.

    1991-01-01

    An 18-month study of the use of the Blind Learning Aptitude Test at schools for visually impaired children in England and Wales found the test to be culturally fair and appropriate for use with children for whom English is a second language. Scores are compared with standardization data for visually impaired children in the United States.…

  17. Test Results From a High Power Linear Alternator Test Rig

    Science.gov (United States)

    Birchenough, Arthur G.; Hervol, David S.; Gardner, Brent G.

    2010-01-01

    Stirling cycle power conversion is an enabling technology that provides high thermodynamic efficiency but also presents unique challenges with regard to electrical power generation, management, and distribution. The High Power Linear Alternator Test Rig (HPLATR) located at the NASA Glenn Research Center (GRC) in Cleveland, Ohio is a demonstration test bed that simulates electrical power generation from a Stirling engine driven alternator. It implements the high power electronics necessary to provide a well regulated DC user load bus. These power electronics use a novel design solution that includes active rectification and power factor control, active ripple suppression, along with a unique building block approach that permits the use of high voltage or high current alternator designs. This report describes the HPLATR, the test program, and the operational results.

  18. Synthesis of low cycle fatigue test results

    International Nuclear Information System (INIS)

    Andrews, R.M.

    1990-01-01

    Axial strain controlled cycle fatigue tests were carried out on type 316 stainless steel parent metal, vacuum and non-vacuum electron beams welds, submerged arc welds and gas shielded metal arc welds. Testing covered total strains in the range 0.6% to 2%, and was at room temperature and 550 0 C. Parent metal and the electron beam welds showed rapid cyclic hardening, while arc welds showed little hardening. The weld metal cyclic stress-strain response was above that obtained for the parent metal, although below data obtained by other workers for similar parent materials. Weld metal endurances were above the ASME N47 continuous cycling design line at both temperatures, and comparable with parent metal data. However, the weld metal data approached the design line at low strain ranges (around 0.5%). Endurances were predicted from crack growth rates estimated from striation spacings, giving acceptable results except for the gas shielded metal arc weldments. (author)

  19. Partial-array test results in IFSMTF

    International Nuclear Information System (INIS)

    Lue, J.W.; Dresner, L.; Koizumi, K.; Lubell, M.S.; Luton, J.N.; Shen, S.S.; Zahn, G.R.; Zichy, J.A.

    1985-01-01

    Preliminary performance tests of two large superconducting magnets have been carried out in the International Fusion Superconducting Magnet Test Facility (IFSMTF). Each of the Japanese (JA) and General Dynamics/Convair (GD) coils was operated up to its full design current of 10.2 kA with the other serving as an adjacent background coil at 40% of design current. Cryostatic stability was demonstrated for both coils by noting recovery from a full half-turn (5 m) driven normal. A new pick-up coil compensation scheme was successfully used for the quench detection system. Each coil remained superconducting when the other was dumped. Unique instrumentation was used to measure changes in bore dimensions and displacement of the winding from the coil case. Agreement between structural analysis and measurement of bore dimension changes resulting from magnetic loads is good. The Swiss (CH) coil underwent only a cryogenic test. The forced cooling worked well and an inlet temperature of 3.8 K was demonstrated

  20. Arc melter demonstration baseline test results

    Energy Technology Data Exchange (ETDEWEB)

    Soelberg, N.R.; Chambers, A.G.; Anderson, G.L.; Oden, L.L.; O`Connor, W.K.; Turner, P.C.

    1994-07-01

    This report describes the test results and evaluation for the Phase 1 (baseline) arc melter vitrification test series conducted for the Buried Waste Integrated Demonstration program (BWID). Phase 1 tests were conducted on surrogate mixtures of as-incinerated wastes and soil. Some buried wastes, soils, and stored wastes at the INEL and other DOE sites, are contaminated with transuranic (TRU) radionuclides and hazardous organics and metals. The high temperature environment in an electric arc furnace may be used to process these wastes to produce materials suitable for final disposal. An electric arc furnace system can treat heterogeneous wastes and contaminated soils by (a) dissolving and retaining TRU elements and selected toxic metals as oxides in the slag phase, (b) destroying organic materials by dissociation, pyrolyzation, and combustion, and (c) capturing separated volatilized metals in the offgas system for further treatment. Structural metals in the waste may be melted and tapped separately for recycle or disposal, or these metals may be oxidized and dissolved into the slag. The molten slag, after cooling, will provide a glass/ceramic final waste form that is homogeneous, highly nonleachable, and extremely durable. These features make this waste form suitable for immobilization of TRU radionuclides and toxic metals for geologic timeframes. Further, the volume of contaminated wastes and soils will be substantially reduced in the process.

  1. Boeing's High Voltage Solar Tile Test Results

    Science.gov (United States)

    Reed, Brian J.; Harden, David E.; Ferguson, Dale C.; Snyder, David B.

    2002-01-01

    Real concerns of spacecraft charging and experience with solar array augmented electrostatic discharge arcs on spacecraft have minimized the use of high voltages on large solar arrays despite numerous vehicle system mass and efficiency advantages. Boeing's solar tile (patent pending) allows high voltage to be generated at the array without the mass and efficiency losses of electronic conversion. Direct drive electric propulsion and higher power payloads (lower spacecraft weight) will benefit from this design. As future power demand grows, spacecraft designers must use higher voltage to minimize transmission loss and power cable mass for very large area arrays. This paper will describe the design and discuss the successful test of Boeing's 500-Volt Solar Tile in NASA Glenn's Tenney chamber in the Space Plasma Interaction Facility. The work was sponsored by NASA's Space Solar Power Exploratory Research and Technology (SERT) Program and will result in updated high voltage solar array design guidelines being published.

  2. What is Color Blindness?

    Science.gov (United States)

    ... Stories Español Eye Health / Eye Health A-Z Color Blindness Sections What Is Color Blindness? What Are ... Treatment How Color Blindness Is Tested What Is Color Blindness? Leer en Español: ¿Qué es el daltonismo? ...

  3. Full length prototype SSC dipole test results

    International Nuclear Information System (INIS)

    Strait, J.; Brown, B.C.; Carson, J.

    1987-01-01

    Results are presented from tests of the first full length prototype SSC dipole magnet. The cryogenic behavior of the magnet during a slow cooldown to 4.5K and a slow warmup to room temperature has been measured. Magnetic field quality was measured at currents up to 2000 A. Averaged over the body field all harmonics with the exception of b 2 and b 8 are at or within the tolerances specified by the SSC Central Design Group. (The values of b 2 and b 8 result from known design and construction defects which will be be corrected in later magnets.) Using an NMR probe the average body field strength is measured to be 10.283 G/A with point to point variations on the order of one part in 1000. Data are presented on quench behavior of the magnet up to 3500 A (approximately 55% of full field) including longitudinal and transverse velocities for the first 250 msec of the quench

  4. Honeycomb spacer crush stength test results

    Energy Technology Data Exchange (ETDEWEB)

    Leader, D.R.

    1993-09-15

    This report discusses aluminum honeycomb spacers, which are used as an energy absorbent material in shipping packages for off site shipment of radioactive materials and which were ordered in two crush strengths, 1,000 psi and 2,000 psi for use in drop tests requested by the Packaging and Transportation group as part of the shipping container rectification process. Both the group as part of the shipping container rectification process. Both the vendor and the SRTC Materials Laboratory performed crush strength measurements on test samples made from the material used to fabricate the actual spacers. The measurements of crush strength made in the SRTC Materials Laboratory are within 100 psi of the measurements made by the manufacturer for all samples tested and all test measurements are within 10% of the specified crush strength, which is acceptable to the P&T group for the planned tests.

  5. The Assessment of Cognitive Development in Blind Infants and Preschoolers.

    Science.gov (United States)

    Brambring, M.; Troster, H.

    1994-01-01

    This study evaluated the Bielefeld Developmental Test for Blind Infants and Preschoolers by comparing cognitive performance of blind and sighted children (ages three and four). Results indicated that even this test (with "blind-neutral" items) did not permit a fair comparative assessment, though it did prove suitable for within-group…

  6. Microbial soil community analyses for forensic science: Application to a blind test.

    Science.gov (United States)

    Demanèche, Sandrine; Schauser, Leif; Dawson, Lorna; Franqueville, Laure; Simonet, Pascal

    2017-01-01

    Soil complexity, heterogeneity and transferability make it valuable in forensic investigations to help obtain clues as to the origin of an unknown sample, or to compare samples from a suspect or object with samples collected at a crime scene. In a few countries, soil analysis is used in matters from site verification to estimates of time after death. However, up to date the application or use of soil information in criminal investigations has been limited. In particular, comparing bacterial communities in soil samples could be a useful tool for forensic science. To evaluate the relevance of this approach, a blind test was performed to determine the origin of two questioned samples (one from the mock crime scene and the other from a 50:50 mixture of the crime scene and the alibi site) compared to three control samples (soil samples from the crime scene, from a context site 25m away from the crime scene and from the alibi site which was the suspect's home). Two biological methods were used, Ribosomal Intergenic Spacer Analysis (RISA), and 16S rRNA gene sequencing with Illumina Miseq, to evaluate the discriminating power of soil bacterial communities. Both techniques discriminated well between soils from a single source, but a combination of both techniques was necessary to show that the origin was a mixture of soils. This study illustrates the potential of applying microbial ecology methodologies in soil as an evaluative forensic tool. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  7. Supercritical CO2 test loop operation and first test results

    International Nuclear Information System (INIS)

    Wright, Steven A.; Pickard, Paul S.

    2009-01-01

    The DOE Office of Nuclear Energy is investigating advanced Brayton cycles for use with next generation nuclear power plants. The focus of this work is on the supercritical CO 2 Brayton cycle which has the potential for high efficiency, and for reduced capital costs due to very compact turbomachinery. Sandia has fabricated and is operating a supercritical CO 2 (S-CO 2 ) test loop to investigate the key technology issues associated with this cycle. This loop is part of a multi-year phased development program to develop a megawatt (MW) class closed S-CO 2 Brayton cycle to demonstrate the applicability of this cycle for DOE Gen-IV program. The current loop has been configured as both a compression loop and as simple heated but unrecuperated Brayton cycle. A second split-flow or re-compression Brayton cycle is currently under development that will use approximately 1 MW of heat to run the Brayton cycle. Early configurations of this split-flow Brayton cycle will be operational later this fiscal year. The key issues for this cycle include the fundamental issues of compressor fluid performance and system control near the critical point, but also the supporting technology issues of bearings, sealing technologies, and rotor windage losses which are also essential to achieving efficiency and cost objectives. These tests are providing the first measurements and information on these key supercritical CO 2 power conversion systems questions. Important data for all these issues has been obtained. This report presents the major results of the testing by showing and comparing the measured compressor performance map with the predicted performance. The compression loop uses a ∼50 kWe motor driven compressor to spin a 37 mm OD compressor at design speeds up to 75,000 rpm with a pressure ratio of 1.8 and a flow rate of 3.53 kg/s for a compressor inlet condition of 305.3 K and 7690 kPa. The most recent configuration of this loop has added a small turbine and 260 kW of heater power is

  8. Visual perception skills testing: preliminary results

    CSIR Research Space (South Africa)

    Smith, Andrew C

    2009-02-01

    Full Text Available Good visual perception skills are important in the effective manipulation of Tangible User Interfaces. This paper reports on the application of a test set researchers have developed specifically to quantify the visual perception skills of children...

  9. Bilateral compared with unilateral sacral nerve stimulation for faecal incontinence: results of a randomized, single-blinded crossover study.

    Science.gov (United States)

    Duelund-Jakobsen, J; Buntzen, S; Lundby, L; Sørensen, M; Laurberg, S

    2015-12-01

    This randomized single-blinded crossover study aimed to investigate whether bilateral sacral nerve stimulation (SNS) is more efficient than unilateral stimulation for faecal incontinence (FI). Patients with FI who responded during a unilateral test stimulation, with a minimum improvement of 50% were eligible. Twenty-seven patients who were accepted to enter the trial were bilaterally implanted with two permanent leads and pacemakers. Patients were randomized into three periods of 4 weeks' stimulation including unilateral right, unilateral left and bilateral stimulation. Symptoms scores and bowel habit diaries were collected at baseline and in each study period. A 1-week washout was introduced between each study period. Twenty-seven (25 female) patients with a median age of 63 (36-84) years were bilaterally implanted from May 2009 to June 2012. The median number of episodes of FI per 3 weeks significantly decreased from 17 (3-54) at baseline to 2 (0-20) during stimulation on the right side, 2 (0-42) during stimulation on the left side and 1 (0-25) during bilateral stimulation. The Wexner incontinence score improved significantly from a median of 16 (10-20) at baseline to 9 (0-14) with right-side stimulation, 10 (0-15) with left-side stimulation and 9 (0-14) with bilateral stimulation. The differences between unilateral right or unilateral left and bilateral stimulation were non-significant, for FI episodes (P = 0.3) or for Wexner incontinence score (P = 0.9). Bilateral SNS therapy for FI is not superior to standard unilateral stimulation in the short term. Equal functional results can be obtained regardless of the side of implantation. Colorectal Disease © 2015 The Association of Coloproctology of Great Britain and Ireland.

  10. Ultrasound therapy for recalcitrant diabetic foot ulcers: results of a randomized, double-blind, controlled, multicenter study.

    Science.gov (United States)

    Ennis, William J; Foremann, Phil; Mozen, Neal; Massey, Joi; Conner-Kerr, Teresa; Meneses, Patricio

    2005-08-01

    An estimated 15% of patients with diabetes will develop a foot ulcer sometime in their life, making them 30 to 40 times more likely to undergo amputation due to a non-healing foot ulcer than the non-diabetic population. To determine the safety and efficacy of a new, non-contact, kilohertz ultrasound therapy for the healing of recalcitrant diabetic foot ulcers - as well as to evaluate the impact on total closure and quantitative bacterial cultures and the effect on healing of various levels of sharp/surgical debridement - a randomized, double-blinded, sham-controlled, multicenter study was conducted in hospital-based and private wound care clinics. Patients (55 met criteria for efficacy analysis) received standard of care, which included products that provide a moist environment, offloading diabetic shoes and socks, debridement, wound evaluation, and measurement. The "therapy" was either active 40 KHz ultrasound delivered by a saline mist or a "sham device" which delivered a saline mist without the use of ultrasound. After 12 weeks of care, the proportion of wounds healed (defined as complete epithelialization without drainage) in the active ultrasound therapy device group was significantly higher than that in the sham control group (40.7% versus 14.3%, P = 0.0366, Fisher's exact test). The ultrasound treatment was easy to use and no difference in the number and type of adverse events between the two treatment groups was noted. Of interest, wounds were debrided at baseline followed by a quantitative culture biopsy. The results of these cultures demonstrated a significant bioburden (greater than 10(5)) in the majority of cases, despite a lack of clinical signs of infection. Compared to control, this therapeutic modality was found to increase the healing rate of recalcitrant, diabetic foot ulcers.

  11. Results of Final Focus Test Beam

    Energy Technology Data Exchange (ETDEWEB)

    Walz, Dieter R

    2003-06-13

    The beam experiments of Final Focus Test Beam (FFTB) started in September 1993 at SLAC, and have produced a 1.7 {micro}m x 75 nm spot of 46 GeV electron beam. A number of new techniques involving two nanometer spot-size monitors have been developed. Several beam diagnostic/tuning schemes are applied to achieve and maintain the small spot. This experiment opens the way toward the nanometer world for future linear colliders.

  12. Results of workplace drug testing in Norway

    Directory of Open Access Journals (Sweden)

    Hilde Marie Erøy Lund

    2011-12-01

    Full Text Available Workplace drug testing is less common in Norway than in many other countries. During the period from 2000-2006, 13469 urine or blood samples from employees in the offshore industry, shipping companies and aviation industry were submitted to the Norwegian Institute of Public Health for drug testing. The samples were analysed for benzodiazepines, illicit drugs, muscle relaxants with sedating properties, opioids and z-hypnotics. In total, 2.9% of the samples were positive for one or more substances. During the study period the prevalence decreased for morphine (from 1.9% to 1.1% and increased for amphetamine (from 0.04% to 0.6%, clonazepam (from 0% to 0.1%, methamphetamine (from 0.04% to 0.6%, nitrazepam (from 0% to 0.4% and oxazepam (from 0.5% to 1.3% (p<0.05. There was no significant change in prevalence for the other substances included in the analytical programme. Illicit drugs were significantly associated with lower age (OR: 0.93, p<0.05. This study found low prevalence of drugs among employees in companies with workplace drug testing programmes in Norway.

  13. Aniracetam tested in chronic psychosyndrome after long-term exposure to organic solvents. A randomized, double-blind, placebo-controlled cross-over study with neuropsychological tests.

    Science.gov (United States)

    Somnier, F E; Ostergaard, M S; Boysen, G; Bruhn, P; Mikkelsen, B O

    1990-01-01

    In order to examine if the nootropic drug, aniracetam, was capable of improving cognitive performance, 44 subjects suffering from chronic psychosyndrome after long-term exposure to organic solvents were included in a randomized, double-blind, placebo-controlled, cross-over study. The treatment periods were 3 months with aniracetam 1 g daily and 3 months with placebo. Neuropsychological tests as well as a physical and neurological examination were performed at entry into the study and after each treatment period, together with an evaluation of the subjects' overall condition. Neither the doctors' nor the subjects' own assessment of the overall condition indicated that the trial medication had had any effect. No significant changes in neuropsychological symptoms were observed. A statistically significant difference in favour of antiracetam was found in only 1 of the 19 neuropsychological test measures, namely a test for constructional ability. However, in another test on visuo-spatial function, a statistically significant result was found in favour of placebo. Thus, aniracetam was found to be ineffective in the treatment of subjects suffering from chronic psychosyndrome after long-term exposure to organic solvents.

  14. AMORE Mo-99 Spike Test Results

    Energy Technology Data Exchange (ETDEWEB)

    Youker, Amanda J. [Argonne National Lab. (ANL), Argonne, IL (United States); Krebs, John F. [Argonne National Lab. (ANL), Argonne, IL (United States); Quigley, Kevin J. [Argonne National Lab. (ANL), Argonne, IL (United States); Byrnes, James P. [Argonne National Lab. (ANL), Argonne, IL (United States); Rotsch, David A [Argonne National Lab. (ANL), Argonne, IL (United States); Brossard, Thomas [Argonne National Lab. (ANL), Argonne, IL (United States); Wesolowski, Kenneth [Argonne National Lab. (ANL), Argonne, IL (United States); Alford, Kurt [Argonne National Lab. (ANL), Argonne, IL (United States); Chemerisov, Sergey [Argonne National Lab. (ANL), Argonne, IL (United States); Vandegrift, George F. [Argonne National Lab. (ANL), Argonne, IL (United States)

    2017-09-27

    With funding from the National Nuclear Security Administrations Material Management and Minimization Office, Argonne National Laboratory (Argonne) is providing technical assistance to help accelerate the U.S. production of Mo-99 using a non-highly enriched uranium (non-HEU) source. A potential Mo-99 production pathway is by accelerator-initiated fissioning in a subcritical uranyl sulfate solution containing low enriched uranium (LEU). As part of the Argonne development effort, we are undertaking the AMORE (Argonne Molybdenum Research Experiment) project, which is essentially a pilot facility for all phases of Mo-99 production, recovery, and purification. Production of Mo-99 and other fission products in the subcritical target solution is initiated by putting an electron beam on a depleted uranium (DU) target; the fast neutrons produced in the DU target are thermalized and lead to fissioning of U-235. At the end of irradiation, Mo is recovered from the target solution and separated from uranium and most of the fission products by using a titania column. The Mo is stripped from the column with an alkaline solution. After acidification of the Mo product solution from the recovery column, the Mo is concentrated (and further purified) in a second titania column. The strip solution from the concentration column is then purified with the LEU Modified Cintichem process. A full description of the process can be found elsewhere [1–3]. The initial commissioning steps for the AMORE project include performing a Mo-99 spike test with pH 1 sulfuric acid in the target vessel without a beam on the target to demonstrate the initial Mo separation-and-recovery process, followed by the concentration column process. All glovebox operations were tested with cold solutions prior to performing the Mo-99 spike tests. Two Mo-99 spike tests with pH 1 sulfuric acid have been performed to date. Figure 1 shows the flow diagram for the remotely operated Mo-recovery system for the AMORE project

  15. OPERA Resistive Plate Chambers underground test results

    International Nuclear Information System (INIS)

    Bergnoli, A.; Brugnera, R.; Candela, A.; Carrara, E.; Ciesielski, R.; Dal Corso, F.; Degli Esposti, L.; Di Giovanni, A.; D'Incecco, M.; Di Troia, C.; Dusini, S.; Fanin, C.; Felici, G.; Gambarara, A.; Garfagnini, A.; Gatta, M.; Grianti, F.; Gustavino, C.; Lindozzi, M.; Longhin, A.; Mengucci, A.; Monacelli, P.; Paoloni, A.; Stanco, L.; Tatananni, E.; Terranova, F.; Spinetti, M.; Stipcevic, M.; Sugonyaev, V.; Terminiello, L.; Ventura, M.; Votano, L.

    2006-01-01

    The OPERA experiment [M. Guler et al., CERN/SPSC 2000-028, SPSC/P318, LNGS P25/2000, July 10, 2000; M. Guler et al., CERN/SPSC 2001-025, SPSC/M668, LNGS-EXP 30/2001 Add. 1/01, August 21, 2001] will study ν μ ->ν τ oscillations through τ appearance on the 732 Km long CERN to Gran Sasso baseline. The magnet yokes of the two muon spectrometers are instrumented with 44 layers of high resistivity bakelite Resistive Plate Chambers (RPCs) operated in streamer mode. Each layer covers about 70 m 2 . Four RPC planes were instrumented and the first tests were performed confirming a good behaviour of the installed RPCs in terms of intrinsic noise and operating currents. The measured noise maps agree with those obtained in the extensive quality tests performed at surface. Counting rates are below 20 Hz/m 2 . Single an multiple cosmic muon tracks were also reconstructed. The estimated efficiency is close to the geometrical limit and the very first measurements of the absolute and differential muon flux are in agreement with expectations

  16. RESULTS OF INITIAL AMMONIA OXIDATION TESTING

    Energy Technology Data Exchange (ETDEWEB)

    Nash, C. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Fowley, M. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2016-12-30

    This memo presents an experimental survey of aqueous phase chemical processes to remove aqueous ammonia from waste process streams. Ammonia is generated in both the current Hanford waste flowsheet and in future waste processing. Much ammonia will be generated in the Low Activity Waste (LAW) melters.i Testing with simulants in glass melters at Catholic University has demonstrated the significant ammonia production.ii The primary reaction there is the reducing action of sugar on nitrate in the melter cold cap. Ammonia has been found to be a problem in secondary waste stabilization. Ammonia vapors are noxious and destruction of ammonia could reduce hazards to waste treatment process personnel. It is easily evolved especially when ammonia-bearing solutions are adjusted to high pH.

  17. Tests of a photovoltaic pump: first results

    International Nuclear Information System (INIS)

    Petroselli, A.; Pica, M.; Biondi, P.

    2005-01-01

    The paper deals with a first series of tests conducted in Viterbo (42 deg 25 min North, 12 deg 06 min East) on a PV-DC pump. This series lasted eight months - from the first days of January to the end of August 2003 - and involved measurements of: air and PV-module temperatures; solar radiations, both on horizontal surface and tilted module surface; voltage and intensity of the DC currents from the panel; pump pressures and flow rates. In total, as much as 3,150 data were collected every day. The analysis of the data allowed to obtain some simple empirical relations expressing daily pumped water volumes, instantaneous flow rates and system efficiencies as a function of both radiations and total dynamic heads [it

  18. Middleware for big data processing: test results

    Science.gov (United States)

    Gankevich, I.; Gaiduchok, V.; Korkhov, V.; Degtyarev, A.; Bogdanov, A.

    2017-12-01

    Dealing with large volumes of data is resource-consuming work which is more and more often delegated not only to a single computer but also to a whole distributed computing system at once. As the number of computers in a distributed system increases, the amount of effort put into effective management of the system grows. When the system reaches some critical size, much effort should be put into improving its fault tolerance. It is difficult to estimate when some particular distributed system needs such facilities for a given workload, so instead they should be implemented in a middleware which works efficiently with a distributed system of any size. It is also difficult to estimate whether a volume of data is large or not, so the middleware should also work with data of any volume. In other words, the purpose of the middleware is to provide facilities that adapt distributed computing system for a given workload. In this paper we introduce such middleware appliance. Tests show that this middleware is well-suited for typical HPC and big data workloads and its performance is comparable with well-known alternatives.

  19. THERAPEUTIC EQUIVALENCE OF ORIGINAL CLOPIDOGREL (PLAVIX AND ITS GENERIC (EGITROMB. RESULTS OF COMPARATIVE RANDOMIZED CROSS-OVER BLIND STUDY

    Directory of Open Access Journals (Sweden)

    V. V. Yakusevich

    2011-01-01

    Full Text Available Aim. To study therapeutic equivalence (efficacy, safety and tolerability of original clopidogrel (Plavix and its generic (Egitromb in patients of high cardiovascular risk. Material and methods. Thirty one patients with coronary heart disease and indications for clopidogrel therapy were involved into the randomized cross-over blind study. Half of the patients received original clopidogrel (75 mg daily during the first 2 weeks and then they received generic clopidogrel in the same dose during next 2 weeks. Another half of the patients received the drugs in reverse order. Antiplatelet activity of Plavix and Egitromb was estimated by effects on ADP-induced platelet aggregation initially and after 2 weeks of treatment with each drug. Study blinding was provided by the following approach: doctors of cardiology clinic performed clinical monitoring and drug distribution; coded blood samples for platelet aggregation assessment were studied in independent laboratory of thrombosis; statistical data analysis was performed by biostatistics expert in other research center. Results. 2-week therapy with each drug led to a significant decrease of ADP-induced platelet aggregation which remained low after switching from original drug to generic and vice versa. Aggregation dynamics did not depend on the first administered drug. There were no significant differences between aggregation changes as a result of treatment with original or generic drug. No one adverse event was observed in association with both drugs therapy. Conclusion. Generic drug Egitromb (Egis, Hungary and original clopidogrel Plavix (Sanofi-Aventis, France have equivalent antiplatelet effect.

  20. Using a Force Concept Inventory Test with Visually Impaired and Blind Students

    Science.gov (United States)

    Bulbul, Mustafa Sahin; Garip, Belkis; Özdemir, Ömer Faruk

    2015-01-01

    This paper reports on a study to determine whether blind students' conceptualizations of force and motion differ from sighted students. This is particularly concerned with the question of whether the students' visual experiences have any relation to their conceptualizations or misconceptualization about force and motion. The research was designed…

  1. Results of a round robin test on NDT methods for austenitic pipe welds

    International Nuclear Information System (INIS)

    Neundorf, B.

    2002-01-01

    A research programme sponsored by the German utilities (VGB PowerTech) was performed at MPA Stuttgart between 1993 and 1999. Objectives of the programme were to gain information on the feasibility of evaluation methods and of influential parameters on the results of non-destructive testing. Circumferential weld specimens of typical austenitic pipe or pipe-elbow connections which originate from replaced components of nuclear power plants were investigated in a round robin test. Teams of different NDT vendors and research institutes performed blind tests using ultrasonic testing, radiographic testing (conventional evaluation of films and evaluation of digitised films) or digital radiographic testing. The test pieces consisted of cut-out austenitic weld specimens containing service induced cracks. (orig.) [de

  2. Impact of using a local protocol in preoperative testing: blind randomized clinical trial.

    Science.gov (United States)

    Santos, Mônica Loureiro; Iglesias, Antônio Carlos

    2017-01-01

    to evaluate the impact of the use of a local protocol of preoperative test requests in reducing the number of exams requested and in the occurrence of changes in surgical anesthetic management and perioperative complications. we conducted a randomized, blinded clinical trial at the Gaffrée and Guinle University Hospital with 405 patients candidates for elective surgery randomly divided into two groups, according to the practice of requesting preoperative exams: a group with non-selectively requested exams and a protocol group with exams requested according to the study protocol. Studied exams: complete blood count, coagulogram, glycemia, electrolytes, urea and creatinine, ECG and chest X-ray. Primary outcomes: changes in surgical anesthetic management caused by abnormal exams, reduction of the number of exams requested after the use of the protocol and perioperative complications. there was a significant difference (pprotocolo local de solicitações de exames pré-operatórios na redução do número de exames solicitados e na ocorrência de alterações na conduta anestésico-cirúrgica e de complicações perioperatórias. ensaio clínico randomizado, cego, realizado no Hospital Universitário Gaffrée e Guinle com 405 pacientes candidatos à operação eletiva divididos randomicamente em dois grupos segundo a prática de solicitação de exames pré-operatórios: grupo Rotina com exames solicitados de maneira não seletiva e grupo Protocolo com exames solicitados de acordo com o protocolo em estudo. Exames em estudo: hemograma, coagulograma, glicemia, eletrólitos, ureia e creatinina, ECG e radiografia de tórax. Desfechos primários: alterações na conduta anestésico-cirúrgica motivadas por exames anormais, redução do número de exames solicitados após o uso do protocolo e complicações perioperatórias. foi observada diferença significativa (pprotocolo proposto foi efetivo em eliminar um quantitativo significativo de exames complementares sem indica

  3. Blind Tests of Inversion Package for Stratigraphic Interpretation Test en aveugle de logiciels d'inversion pour l'interprétation stratigraphique

    Directory of Open Access Journals (Sweden)

    Lailly P.

    2006-11-01

    Full Text Available This paper presents the blind test experiment set up for the EAEG workshop on Practical Aspects of Seismic Inversion(Berlin, 1989. The target was to review the possibilities provided by seismic data inversion at the end of the 1980's. This blind test consisted in deriving an acoustic impedance cross-section from a poststack seismic section and an impedance log. The control of the solution was made by comparison of the solution with logs at different well locations, these logs being kept hidden before the workshop. We give a mathematical formulation of the considered seismic inverse problem and we describe in detail the blind test experiment. We present the results obtained during this blind test with two software packages: SPIDER (Elf Aquitaine and INTEGRATE (Jason Geosystems. These results and other results presented during the workshop (see the papers in this issue illustrate the effectiveness of seismic inversion and the importance of integrating geological information during the inversion process. L'inversion de données sismiques est un problème qui a suscité l'intérêt des géophysiciens pendant les dernières décennies (Kunetz, 1963; Bamberger et al, 1977, 1982; Lavergne et Willm, 1977; Gjevik et at, 1976; Lindseth, 1979; Oldenburg et al, 1983; Duijndam et Van Riel, 1980, . . . . L'intérêt de cette approche est de fournir à partir des données sismiques une estimation quantitative des distributions de certains paramètres physiques caractéristiques du sous-sol. De plus certaines de ces méthodes permettent d'intégrer des données non sismiques (données de puits, information géologique pour la construction du résultat. Ces méthodes débouchent donc sur une autre conception de l'interprétation stratigraphique : la section à interpréter est une distribution de paramètre physique (souvent l'impédance acoustique qui est censée intégrer toutes les informations manipulées par l'interprétateur (sismique, diagraphies

  4. Blind test of methods for obtaining 2-D near-surface seismic velocity models from first-arrival traveltimes

    Science.gov (United States)

    Zelt, Colin A.; Haines, Seth; Powers, Michael H.; Sheehan, Jacob; Rohdewald, Siegfried; Link, Curtis; Hayashi, Koichi; Zhao, Don; Zhou, Hua-wei; Burton, Bethany L.; Petersen, Uni K.; Bonal, Nedra D.; Doll, William E.

    2013-01-01

    Seismic refraction methods are used in environmental and engineering studies to image the shallow subsurface. We present a blind test of inversion and tomographic refraction analysis methods using a synthetic first-arrival-time dataset that was made available to the community in 2010. The data are realistic in terms of the near-surface velocity model, shot-receiver geometry and the data's frequency and added noise. Fourteen estimated models were determined by ten participants using eight different inversion algorithms, with the true model unknown to the participants until it was revealed at a session at the 2011 SAGEEP meeting. The estimated models are generally consistent in terms of their large-scale features, demonstrating the robustness of refraction data inversion in general, and the eight inversion algorithms in particular. When compared to the true model, all of the estimated models contain a smooth expression of its two main features: a large offset in the bedrock and the top of a steeply dipping low-velocity fault zone. The estimated models do not contain a subtle low-velocity zone and other fine-scale features, in accord with conventional wisdom. Together, the results support confidence in the reliability and robustness of modern refraction inversion and tomographic methods.

  5. Botulinum toxin to improve results in cleft lip repair: a double-blinded, randomized, vehicle-controlled clinical trial.

    Directory of Open Access Journals (Sweden)

    Chun-Shin Chang

    Full Text Available Most patients with facial scarring would value even a slight improvement in scar quality. Botulinum toxin A is widely used to alleviate facial dynamic rhytides but is also believed to improve scar quality by reducing wound tension during healing. The main objective was to assess the effect of Botulinum toxin on scars resultant from standardized upper lip wounds.In this double-blinded, randomized, vehicle-controlled, prospective clinical trial, 60 consecutive consenting adults undergoing cleft lip scar revision (CLSR surgery between July 2010 and March 2012 were randomized to receive botulinum toxin A (n = 30 or vehicle (normal saline; n = 30 injections into the subjacent orbicularis oris muscle immediately after wound closure. Scars were independently assessed at 6-months follow-up in blinded fashion using: Vancouver Scar Scale (VSS, Visual Analogue Scale (VAS and photographic plus ultrasound measurements of scar widths.58 patients completed the trial. All scar assessment modalities revealed statistically significantly better scars in the experimental than the vehicle-control group.Quality of surgical upper lip scars, which are oriented perpendicular to the direction of pull of the underlying orbicularis oris muscle, is significantly improved by its temporary paralysis during wound healing.ClinicalTrials.gov NCT01429402.

  6. Avaliação educacional por meio do teste iar em escolares com cegueira Scholastic achievement assessment of blind students using the iar test

    Directory of Open Access Journals (Sweden)

    Suzana Rabello

    2007-08-01

    the study. During a six month period the students were assessed using the Instrument to Assess Basic Literacy Repertoire (IAR; the instrument was transcribed in Braille, also having raised images when applicable. Results of the IAR application showed that T.A.M. achieved 100% accuracy for all concepts; A.M. and D.A.C. achieved 100% accuracy for body scheme, laterality and word verbalization; D.A.C. achieved 50% for the concepts of position, size and quantity; A.M. achieved 50% for hearing discrimination; D.A.C. obtained a rate of less than 50% for concepts of direction, space, shape, tactile discrimination, hearing discrimination, analysis/synthesis and fine motor coordination; A.M. also achieved less than 50% success rate for direction, tactile discrimination, analysis/synthesis and fine motor coordination concepts. As to applicability, the IAR Test was shown to be effective in assessing blind students; it offers useful orientation to professionals and family members who wish to adopt stimulation and strategies that enhance their development.

  7. Oats in the Diet of Children with Celiac Disease: Preliminary Results of a Double-Blind, Randomized, Placebo-Controlled Multicenter Italian Study

    Science.gov (United States)

    Gatti, Simona; Caporelli, Nicole; Galeazzi, Tiziana; Francavilla, Ruggiero; Barbato, Maria; Roggero, Paola; Malamisura, Basilio; Iacono, Giuseppe; Budelli, Andrea; Gesuita, Rosaria; Catassi, Carlo; Lionetti, Elena

    2013-01-01

    A gluten-free diet (GFD) is currently the only available treatment for patients with celiac disease (CD). Several clinical trials have demonstrated that most celiac patients can tolerate a medium-high quantity of oats without any negative clinical effects; however, the inclusion of oats in GFD is still a matter of debate. In this study, Italian children with CD were enrolled in a 15-month, randomized, double-blind, placebo-controlled multicenter trial. Participants were randomized in two groups following either A-B treatment (6 months of diet “A”, 3 months of standard GFD, 6 months of diet “B”), or B-A treatment (6 months of diet “B”, 3 months of standard GFD, 6 months of diet “A”). A and B diets included gluten-free (GF) products (flour, pasta, biscuits, cakes and crisp toasts) with either purified oats or placebo. Clinical data (Gastrointestinal Symptoms Rate Scale [GSRS] score) and intestinal permeability tests (IPT), were measured through the study period. Although the study is still blinded, no significant differences were found in GSRS score or the urinary lactulose/mannitol (L/M) ratio between the two groups after 6 months of treatment. These preliminary results suggest that the addition of non-contaminated oats from selected varieties in the treatment of children with CD does not determine changes in intestinal permeability and gastrointestinal symptoms. PMID:24264227

  8. Oats in the Diet of Children with Celiac Disease: Preliminary Results of a Double-Blind, Randomized, Placebo-Controlled Multicenter Italian Study

    Directory of Open Access Journals (Sweden)

    Simona Gatti

    2013-11-01

    Full Text Available A gluten-free diet (GFD is currently the only available treatment for patients with celiac disease (CD. Several clinical trials have demonstrated that most celiac patients can tolerate a medium-high quantity of oats without any negative clinical effects; however, the inclusion of oats in GFD is still a matter of debate. In this study, Italian children with CD were enrolled in a 15-month, randomized, double-blind, placebo-controlled multicenter trial. Participants were randomized in two groups following either A-B treatment (6 months of diet “A”, 3 months of standard GFD, 6 months of diet “B”, or B-A treatment (6 months of diet “B”, 3 months of standard GFD, 6 months of diet “A”. A and B diets included gluten-free (GF products (flour, pasta, biscuits, cakes and crisp toasts with either purified oats or placebo. Clinical data (Gastrointestinal Symptoms Rate Scale [GSRS] score and intestinal permeability tests (IPT, were measured through the study period. Although the study is still blinded, no significant differences were found in GSRS score or the urinary lactulose/mannitol (L/M ratio between the two groups after 6 months of treatment. These preliminary results suggest that the addition of non-contaminated oats from selected varieties in the treatment of children with CD does not determine changes in intestinal permeability and gastrointestinal symptoms.

  9. The opiate antagonist, naltrexone, in the treatment of trichotillomania: results of a double-blind, placebo-controlled study.

    Science.gov (United States)

    Grant, Jon E; Odlaug, Brian L; Schreiber, Liana R N; Kim, Suck Won

    2014-02-01

    Trichotillomania (TTM) is characterized by repetitive hair pulling resulting in hair loss. Data on the pharmacological treatment of TTM are limited. This study examined the opioid antagonist, naltrexone, in adults with TTM who had urges to pull their hair. Fifty-one individuals with TTM were randomized to naltrexone or placebo in an 8-week, double-blind trial. Subjects were assessed with measures of TTM severity and selected cognitive tasks. Naltrexone failed to demonstrate significantly greater reductions in hair pulling compared to placebo. Cognitive flexibility, however, significantly improved with naltrexone (P = 0.026). Subjects taking naltrexone with a family history of addiction showed a greater numerical reduction in the urges to pull, although it was not statistically significant. Future studies will have to examine whether pharmacological modulation of the opiate system may provide promise in controlling pulling behavior in a subgroup of individuals with TTM.

  10. 49 CFR 199.229 - Reporting of alcohol testing results.

    Science.gov (United States)

    2010-10-01

    ... ALCOHOL TESTING Alcohol Misuse Prevention Program § 199.229 Reporting of alcohol testing results. (a) Each... 49 Transportation 3 2010-10-01 2010-10-01 false Reporting of alcohol testing results. 199.229... alcohol testing results using the Management Information System (MIS) form and instructions as required by...

  11. Interpreting Results from the Standardized UXO Test Sites

    National Research Council Canada - National Science Library

    May, Michael; Tuley, Michael

    2007-01-01

    ...) and the Environmental Security Technology Certification Program (ESCTP) to complete a detailed analysis of the results of testing carried out at the Standardized Unexploded Ordnance (UXO) Test Sites...

  12. Drug and alcohol testing results 2000 annual report

    Science.gov (United States)

    2001-12-01

    The Drug and Alcohol Testing Results 2000 Annual Report is a compilation and analysis of drug and alcohol testing results reported by transit systems in the United State during 2000. The report covers results for the following drug types: marijuana (...

  13. Drug and alcohol testing results 1999 annual report

    Science.gov (United States)

    2000-12-01

    The Drug and Alcohol Testing Results 1999 Annual Report is a compilation and analysis of drug and alcohol testing results reported by transit systems in the United States during 1999. The report covers results for the following drug types: marijuana ...

  14. Drug and alcohol testing results 1998 annual report

    Science.gov (United States)

    1999-12-01

    The Drug and Alcohol Testing Results 1998 Annual Report is a compilation and analysis of drug and alcohol testing results reported by transit systems in the United States during 1998. The report covers results for the following drug types: marijuana ...

  15. Does acetaminophen/hydrocodone affect cold pulpal testing in patients with symptomatic irreversible pulpitis? A prospective, randomized, double-blind, placebo-controlled study.

    Science.gov (United States)

    Fowler, Sara; Fullmer, Spencer; Drum, Melissa; Reader, Al

    2014-12-01

    The purpose of this prospective randomized, double-blind, placebo-controlled study was to determine the effects of a combination dose of 1000 mg acetaminophen/10 mg hydrocodone on cold pulpal testing in patients experiencing symptomatic irreversible pulpitis. One hundred emergency patients in moderate to severe pain diagnosed with symptomatic irreversible pulpitis of a mandibular posterior tooth randomly received, in a double-blind manner, identical capsules of either a combination of 1000 mg acetaminophen/10 hydrocodone or placebo. Cold testing with Endo-Ice (1,1,1,2 tetrafluoroethane; Hygenic Corp, Akron, OH) was performed at baseline and every 10 minutes for 60 minutes. Pain to cold testing was recorded by the patient using a Heft-Parker visual analog scale. Patients' reaction to the cold application was also rated. Cold testing at baseline and at 10 minutes resulted in severe pain for both the acetaminophen/hydrocodone and placebo groups. Although pain ratings decreased from 20-60 minutes, the ratings still resulted in moderate pain. Patient reaction to cold testing showed that 56%-62% had a severe reaction. Although the reactions decreased in severity over the 60 minutes, 20%-34% still had severe reactions at 60 minutes. Regarding pain and patients' reactions to cold testing, there were no significant differences between the combination acetaminophen/hydrocodone and placebo groups at any time period. A combination dose of 1000 mg of acetaminophen/10 mg of hydrocodone did not statistically affect cold pulpal testing in patients presenting with symptomatic irreversible pulpitis. Patients experienced moderate to severe pain and reactions to cold testing. Copyright © 2014 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

  16. [Azelaic acid 15% gel in the treatment of acne vulgaris. Combined results of two double-blind clinical comparative studies].

    Science.gov (United States)

    Gollnick, Harald P M; Graupe, Klaus; Zaumseil, Rolf-Peter

    2004-10-01

    Topical measures are still the mainstay in the therapy of mild-to-moderate acne vulgaris. Azelaic acid 20% in a cream formulation has been established as an efficacious and safe topical drug for 15 years. A new non-alcoholic hydrogel formulation containing 15% azelaic acid was clinically tested against two standard drugs--5% benzoyl peroxide (BPO) and 1% clindamycin. In two independent, randomized, blinded comparative trials 15% azelaic acid gel was clinically tested against 5% benzoyl peroxide (BPO) gel in 351 patients and against 1% clindamycin gel in 229 patients. The drugs were applied b.i.d. for 4 months. Azelaic acid 15% gel proved to be as effective as BPO and clindamycin with median % reduction of the inflamed lesion (papules and pustules) of 70%, and 71% respectively. The azelaic acid gel was well-tolerated, the side effects (local burning and irritation) were distinctly less than with BPO but more pronounced than with clindamycin. Despite these side effects, the treatment was well-accepted by the majority of patients. Azelaic acid gel is an effective topical monotherapy for mild-to-moderate acne vulgaris; its new gel form is an enrichment of acne therapy.

  17. Does Bacopa monnieri improve memory performance in older persons? Results of a randomized, placebo-controlled, double-blind trial.

    Science.gov (United States)

    Morgan, Annette; Stevens, John

    2010-07-01

    The objective of this study was to investigate the effectiveness of Bacopa monnieri Linn. for improvement of memory performance in healthy older persons. This was a randomized, double-blind, placebo-controlled trial. The trial took place in Lismore, NSW, Australia between February and July 2005. Ninety-eight (98) healthy participants over 55 years of age were recruited from the general population. Participants were randomized to receive an extract of Bacopa monnieri called BacoMind(TM) (Natural Remedies Pvt. Ltd.), 300 mg/day, or an identical placebo. Following screening, neuropsychologic and subjective memory assessments were performed at baseline and at 12 weeks. Audioverbal and visual memory performance were measured by the Rey Auditory Verbal Learning Test (AVLT), the Rey-Osterrieth Complex Figure Test (CFT), and the Reitan Trail Making Test (TMT). Subjective memory performance was measured by the Memory Complaint Questionnaire (MAC-Q). One hundred and thirty-six (136) subjects volunteered; 103 met entry criteria, 98 commenced, and 81 completed the trial. Bacopa significantly improved verbal learning, memory acquisition, and delayed recall as measured by the AVLT: trial a4 (p = 0.000), trial a5 (p = 0.016); trial a6 (p = 0.000); trial a7 (delayed recall) (p = 0.001); total learning (p = 0.011); and retroactive interference (p = 0.048). CFT, MAC-Q, and TMT scores improved but group differences were not significant. Bacopa versus placebo caused gastrointestinal tract (GIT) side-effects. Bacopa significantly improved memory acquisition and retention in healthy older Australians. This concurs with previous findings and traditional use. Bacopa caused GIT side-effects of increased stool frequency, abdominal cramps, and nausea.

  18. Mirtazapine does not improve sleep disorders in Alzheimer's disease: results from a double-blind, placebo-controlled pilot study.

    Science.gov (United States)

    Scoralick, Francisca M; Louzada, Luciana L; Quintas, Juliana L; Naves, Janeth O S; Camargos, Einstein F; Nóbrega, Otávio T

    2017-03-01

    The aim of this study was to test the efficacy and safety of mirtazapine in the treatment of sleep disorders in patients with Alzheimer's disease by means of a randomized, double-blind, placebo-controlled trial. Measurements were obtained for 7 days before intervention (baseline) and for 2 weeks after the onset of treatment. Alzheimer's disease patients with sleep disorders (n = 24) received 15-mg mirtazapine (n = 8) or placebo (n = 16) once daily at 2100 hours for 2 weeks. Patients were evaluated with actigraphy and structured scales before and after intervention. Historical control was employed. Treatment with mirtazapine or placebo had no effect on cognitive and functional status as assessed by the Mini-Mental State Examination and the Katz scale, respectively. There were no differences between groups in the frequency or severity of the adverse events reported. Compared with the placebo group, mirtazapine users showed increased daytime sleepiness but no improvement in the duration or efficiency of nocturnal sleep after treatment. This study showed no significant therapeutic effects of 15-mg mirtazapine in community-dwelling Alzheimer's disease patients with sleep disorders. Instead, this study found evidence of worsening of daytime sleep patterns. © 2016 The Authors. Psychogeriatrics © 2016 Japanese Psychogeriatric Society.

  19. Irradiation effects test series, test IE-5. Test results report. [PWR

    Energy Technology Data Exchange (ETDEWEB)

    Croucher, D. W.; Yackle, T. R.; Allison, C. M.; Ploger, S. A.

    1978-01-01

    Test IE-5, conducted in the Power Burst Facility at the Idaho National Engineering Laboratory, employed three 0.97-m long pressurized water reactor type fuel rods, fabricated from previously irradiated zircaloy-4 cladding and one similar rod fabricated from unirradiated cladding. The objectives of the test were to evaluate the influence of simulated fission products, cladding irradiation damage, and fuel rod internal pressure on pellet-cladding interaction during a power ramp and on fuel rod behavior during film boiling operation. The four rods were subjected to a preconditioning period, a power ramp to an average fuel rod peak power of 65 kW/m, and steady state operation for one hour at a coolant mass flux of 4880 kg/s-m/sup 2/ for each rod. After a flow reduction to 1800 kg/s-m/sup 2/, film boiling occurred on one rod. Additional flow reductions to 970 kg/s-m/sup 2/ produced film boiling on the three remaining fuel rods. Maximum time in film boiling was 80s. The rod having the highest initial internal pressure (8.3 MPa) failed 10s after the onset of film boiling. A second rod failed about 90s after reactor shutdown. The report contains a description of the experiment, the test conduct, test results, and results from the preliminary postirradiation examination. Calculations using a transient fuel rod behavior code are compared with the test results.

  20. A single-blind randomised controlled trial of the effects of a web-based decision aid on self-testing for cholesterol and diabetes. study protocol

    Directory of Open Access Journals (Sweden)

    Ickenroth Martine HP

    2012-01-01

    Full Text Available Abstract Background Self-tests, tests on body materials to detect medical conditions, are widely available to the general public. Self-testing does have advantages as well as disadvantages, and the debate on whether self-testing should be encouraged or rather discouraged is still ongoing. One of the concerns is whether consumers have sufficient knowledge to perform the test and interpret the results. An online decision aid (DA with information on self-testing in general, and test specific information on cholesterol and diabetes self-testing was developed. The DA aims to provide objective information on these self-tests as well as a decision support tool to weigh the pros and cons of self-testing. The aim of this study is to evaluate the effect of the online decision aid on knowledge on self-testing, informed choice, ambivalence and psychosocial determinants. Methods/Design A single blind randomised controlled trial in which the online decision aid 'zelftestwijzer' is compared to short, non-interactive information on self-testing in general. The entire trial will be conducted online. Participants will be selected from an existing Internet panel. Consumers who are considering doing a cholesterol or diabetes self-test in the future will be included. Outcome measures will be assessed directly after participants have viewed either the DA or the control condition. Weblog files will be used to record participants' use of the decision aid. Discussion Self-testing does have important pros and cons, and it is important that consumers base their decision whether they want to do a self-test or not on knowledge and personal values. This study is the first to evaluate the effect of an online decision aid for self-testing. Trial registration Dutch Trial Register: NTR3149

  1. A single-blind randomised controlled trial of the effects of a web-based decision aid on self-testing for cholesterol and diabetes. Study protocol.

    Science.gov (United States)

    Ickenroth, Martine H P; Grispen, Janaica E J; de Vries, Nanne K; Dinant, Geert-Jan; Elwyn, Glyn; Ronda, Gaby; van der Weijden, Trudy

    2012-01-04

    Self-tests, tests on body materials to detect medical conditions, are widely available to the general public. Self-testing does have advantages as well as disadvantages, and the debate on whether self-testing should be encouraged or rather discouraged is still ongoing. One of the concerns is whether consumers have sufficient knowledge to perform the test and interpret the results. An online decision aid (DA) with information on self-testing in general, and test specific information on cholesterol and diabetes self-testing was developed. The DA aims to provide objective information on these self-tests as well as a decision support tool to weigh the pros and cons of self-testing. The aim of this study is to evaluate the effect of the online decision aid on knowledge on self-testing, informed choice, ambivalence and psychosocial determinants. A single blind randomised controlled trial in which the online decision aid 'zelftestwijzer' is compared to short, non-interactive information on self-testing in general. The entire trial will be conducted online. Participants will be selected from an existing Internet panel. Consumers who are considering doing a cholesterol or diabetes self-test in the future will be included. Outcome measures will be assessed directly after participants have viewed either the DA or the control condition. Weblog files will be used to record participants' use of the decision aid. Self-testing does have important pros and cons, and it is important that consumers base their decision whether they want to do a self-test or not on knowledge and personal values. This study is the first to evaluate the effect of an online decision aid for self-testing. Dutch Trial Register: NTR3149.

  2. Legal provisions governing the acknowledgement of test results

    International Nuclear Information System (INIS)

    Strecker, A.

    1982-01-01

    The legal provisions governing the acknowledgment of test results are most frequently applied by administrative orders (design and qualification approvals or specimen testing and approval) and are thus claimable and voidable in accordance with general administrative law. The acknowledgment of test certificates requires a legal basis. Test results, however, can be acknowledged also by administrative bodies. Recently, the Federal Government began to delegate more of its legal authority in this field to private institutions, allowing test results to be acknowledged and test certificates to be issued by government controlled private institutions. (orig.) [de

  3. Legal provisions governing the acknowledgment of test results

    International Nuclear Information System (INIS)

    Strecker, A.

    1982-01-01

    The legal provisions governing the acknowledgment of test results are most frequently applied by administrative orders (design and qualification approvals or specimen testing and approval) and are thus claimable and voidable in accordance with general administrative law. The acknowledgment of test certificates requires a legal basis. Test results, however, can be acknowledged also by administrative bodies. Recently, the Federal Government began to delegate more of its legal authority in this field to private institutions, allowing test results to be acknowledged and test certificates to be issued by government controlled private institutions. (orig.) [de

  4. New test methods for BIPV. Results from IP performance

    International Nuclear Information System (INIS)

    Jol, J.C.; Van Kampen, B.J.M.; De Boer, B.J.; Reil, F.; Geyer, D.

    2009-11-01

    Within the Performance project new test procedures for PV building products and the building performance as a whole when PV is applied in buildings have been drafted. It has resulted in a first draft of new test procedures for PV building products and proposals for tests for novel BIPV technology like thin film. The test proposed are a module breakage test for BIPV products, a fire safety test for BIPV products and a dynamic load test for BIPV products. Furthermore first proposals of how flexible PV modules could be tested in an appropriate way to ensure long time quality and safety of these new products are presented.

  5. Enhanced tactile encoding and memory recognition in congenital blindness.

    Science.gov (United States)

    D'Angiulli, Amedeo; Waraich, Paul

    2002-06-01

    Several behavioural studies have shown that early-blind persons possess superior tactile skills. Since neurophysiological data show that early-blind persons recruit visual as well as somatosensory cortex to carry out tactile processing (cross-modal plasticity), blind persons' sharper tactile skills may be related to cortical re-organisation resulting from loss of vision early in their life. To examine the nature of blind individuals' tactile superiority and its implications for cross-modal plasticity, we compared the tactile performance of congenitally totally blind, low-vision and sighted children on raised-line picture identification test and re-test, assessing effects of task familiarity, exploratory strategy and memory recognition. What distinguished the blind from the other children was higher memory recognition and higher tactile encoding associated with efficient exploration. These results suggest that enhanced perceptual encoding and recognition memory may be two cognitive correlates of cross-modal plasticity in congenital blindness.

  6. Drug and alcohol testing results : 1997 annual report

    Science.gov (United States)

    1998-12-01

    The Drug and Alcohol Testing Results 1997 Annual Report is a compilation and analysis of mass transit drug and alcohol testing reported by transit systems in the United States during 1997. The report covers testing results for the following drug type...

  7. Evaluation of intralesional injection of hyaluronic acid compared with verapamil in Peyronie's disease: preliminary results from a prospective, double-blinded, randomized study.

    Science.gov (United States)

    Favilla, V; Russo, G I; Zucchi, A; Siracusa, G; Privitera, S; Cimino, S; Madonia, M; Cai, T; Cavallini, G; Liguori, G; D'Achille, G; Silvani, M; Franco, G; Verze, P; Palmieri, A; Torrisi, B; Mirone, V; Morgia, G

    2017-07-01

    Several intralesional therapeutic protocols have been proposed for the treatment of Peyronie's disease. Among all, hyaluronic acid (HA) and verapamil have been differently tested. We aimed to evaluate the efficacy of intralesional verapamil (ILVI) compared with intralesional HA in patients with early onset of Peyronie's disease (PD). This is a multi-centre prospective double-arm, randomized, double-blinded study comparing ILVI vs. intralesional HA after 12-weeks. Sexually active men, older than 18 years and affected by the acute phase of PD were eligible for this study. Patients have been double-blinded randomly divided into two groups (1 : 1 ratio): Group A received intralesional treatment with Verapamil (10 mg in 5 mL of normal saline water) weekly for 12 weeks, while group B received intralesional treatment with HA (0.8% highly purified sodium salt HA 16 mg/2 mL) weekly for 12 weeks. The primary efficacy outcome was the change from the baseline to the endpoint (12 weeks after therapy) for the penile curvature (degree). The secondary outcome was the change in the plaque size and in the International Index of erectile Function (IIEF-5) score. The difference between post- and pre-treatment plaque size was -1.36 mm (SD ± 1.27) for Group A and -1.80 mm (SD ± 2.47) for Group B (p-value = NS). IIEF-5 increased of 1.46 points (SD ± 2.18) in Group A and 1.78 (SD ± 2.48) in Group B (p-value ± NS). No difference in penile curvature was observed in Group A, while in Group B the penile curvature decreased of 4.60° (SD ± 5.63) from the baseline (p < 0.001) and vs. Group A. According to PGI-I results, we found significant difference as concerning patient global impression of improvement (PGI-I) (4.0 vs. 2.0; p < 0.05). This prospective, double-arm, randomized, double-blinded study comparing ILVI vs. HA as intralesional therapy showed greater efficacy of HA in terms of penile curvature and PGI-I. © 2017 American Society of Andrology and

  8. Effects of PEMF on patients with osteoarthritis: Results of a prospective, placebo-controlled, double-blind study.

    Science.gov (United States)

    Wuschech, Heinz; von Hehn, Ulrike; Mikus, Eberhard; Funk, Richard H

    2015-12-01

    This study aimed to evaluate effects of pulsed electromagnetic fields (PEMF) in a double blind study on patients with knee joint osteoarthritis. The MAGCELL ARTHRO electrode-less therapy delivered a sinusoidal magnetic field, varying in frequency between 4 and 12 Hz. In 1 cm tissue depth, magnetic flux density was 105 mT. A total of n = 57 patients were randomly assigned to the verum, PEMF or placebo group (placebo device). Their average age was 61.6 ± 12.0 years. According to American College of Rheumatology criteria the osteoarthritis level was 2.8 ± 0.8. Treatment was performed twice a day for 5 min over a period of 18 days. Treatment with the MAGCELL device versus control (sham exposed) showed a highly significant reduction in pain (P PEMF lead to highly significant better results in the treatment group compared to the placebo group with regard to the total WOMAC global score and especially for visual analogue scale. Patient assessment of the "effectiveness" was rated in 29.5% as very good and good in 27.3% compared to 0.0% and 15.4% in controls. This therapy is thus a useful complementary treatment option with no side effects. © 2015 Wiley Periodicals, Inc.

  9. Drug and alcohol testing results 1996 annual report

    Science.gov (United States)

    1997-12-01

    The report is a compilation and analysis of mass transit drug and alcohol testing reported by transit systems in the United States during 1996. The report covers testing results for the following drug types: marijuana (THC), cocaine, phencyclidine (P...

  10. Results from the 2013 drug and alcohol testing survey.

    Science.gov (United States)

    2015-12-01

    This report summarizes the results of the 2013 Federal Motor Carrier Safety Administration (FMCSA) Drug and Alcohol Testing Survey. This annual survey measures the percentage of drivers with commercial drivers licenses (CDLs) that test positive fo...

  11. Results from the 2008 Drug and Alcohol Testing Survey

    Science.gov (United States)

    2010-01-01

    This report summarizes the results of the 2008 Federal Motor Carrier Safety Administration Drug and Alcohol Testing Survey. This annual survey measures the percentage of drivers with commercial drivers licenses who test positive for controlled sub...

  12. Distribution of the two-sample t-test statistic following blinded sample size re-estimation.

    Science.gov (United States)

    Lu, Kaifeng

    2016-05-01

    We consider the blinded sample size re-estimation based on the simple one-sample variance estimator at an interim analysis. We characterize the exact distribution of the standard two-sample t-test statistic at the final analysis. We describe a simulation algorithm for the evaluation of the probability of rejecting the null hypothesis at given treatment effect. We compare the blinded sample size re-estimation method with two unblinded methods with respect to the empirical type I error, the empirical power, and the empirical distribution of the standard deviation estimator and final sample size. We characterize the type I error inflation across the range of standardized non-inferiority margin for non-inferiority trials, and derive the adjusted significance level to ensure type I error control for given sample size of the internal pilot study. We show that the adjusted significance level increases as the sample size of the internal pilot study increases. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

  13. Ziprasidone Augmentation of Escitalopram for Major Depressive Disorder: Efficacy Results From a Randomized, Double-Blind, Placebo-Controlled Study.

    Science.gov (United States)

    Papakostas, George I; Fava, Maurizio; Baer, Lee; Swee, Michaela B; Jaeger, Adrienne; Bobo, William V; Shelton, Richard C

    2015-12-01

    The authors sought to test the efficacy of adjunctive ziprasidone in adults with nonpsychotic unipolar major depression experiencing persistent symptoms after 8 weeks of open-label treatment with escitalopram. This was an 8-week, randomized, double-blind, parallel-group, placebo-controlled trial conducted at three academic medical centers. Participants were 139 outpatients with persistent symptoms of major depression after an 8-week open-label trial of escitalopram (phase 1), randomly assigned in a 1:1 ratio to receive adjunctive ziprasidone (escitalopram plus ziprasidone, N=71) or adjunctive placebo (escitalopram plus placebo, N=68), with 8 weekly follow-up assessments. The primary outcome measure was clinical response, defined as a reduction of at least 50% in score on the 17-item Hamilton Depression Rating Scale (HAM-D). The Hamilton Anxiety Rating scale (HAM-A) and Visual Analog Scale for Pain were defined a priori as key secondary outcome measures. Rates of clinical response (35.2% compared with 20.5%) and mean improvement in HAM-D total scores (-6.4 [SD=6.4] compared with -3.3 [SD=6.2]) were significantly greater for the escitalopram plus ziprasidone group. Several secondary measures of antidepressant efficacy also favored adjunctive ziprasidone. The escitalopram plus ziprasidone group also showed significantly greater improvement on HAM-A score but not on Visual Analog Scale for Pain score. Ten (14%) patients in the escitalopram plus ziprasidone group discontinued treatment because of intolerance, compared with none in the escitalopram plus placebo group. Ziprasidone as an adjunct to escitalopram demonstrated antidepressant efficacy in adult patients with major depressive disorder experiencing persistent symptoms after 8 weeks of open-label treatment with escitalopram.

  14. Efficacy and safety of morinidazole in pelvic inflammatory disease: results of a multicenter, double-blind, randomized trial.

    Science.gov (United States)

    Cao, C; Luo, A; Wu, P; Weng, D; Zheng, H; Wang, S

    2017-07-01

    This multicenter, double-blind, randomized, parallel-group, non-inferiority study compared the efficacy and safety of morinidazole with those of ornidazole in women with pelvic inflammatory disease. Women from 18 hospitals in China received a 14-day course of either intravenous morinidazole, 500 mg twice daily (n = 168), or intravenous ornidazole, 500 mg twice daily (n = 170). A total of 312 of 338 patients in the full analysis set (FAS) (92.3%) were included in the per protocol set (PPS) analyses, 61 (19.6%) of whom were included in the microbiologically valid (MBV) population. The clinical resolution rates in the PPS population at the test of cure (TOC, primary efficacy end point, 7-30 days post-therapy) visit were 96.86% (154/159) for morinidazole and 96.73% (148/153) for ornidazole (95% CI: -3.79% to 4.03%). The bacteriological success rates in the MBV population at the TOC visit were 100% (32/32) for morinidazole and 89.66% (26/29) for ornidazole (95% CI: -16.15% to 11.21%). Drug-related adverse events occurred less frequently with morinidazole (32.74%, 55/168) than with ornidazole (47.06%, 80/170) (p pelvic inflammatory disease, twice-daily morinidazole for 14 days was clinically and bacteriologically as efficacious as twice-daily ornidazole for 14 days, while the former was associated with fewer drug-related adverse events than the latter.

  15. Irradiation Effects Test Series: Test IE-2. Test results report. [PWR

    Energy Technology Data Exchange (ETDEWEB)

    Allison, C. M.; Croucher, D. W.; Ploger, S. A.; Mehner, A. S.

    1977-08-01

    The report describes the results of a test using four 0.97-m long PWR-type fuel rods with differences in diametral gap and cladding irradiation. The objective of this test was to provide information about the effects of these differences on fuel rod behavior during quasi-equilibrium and film boiling operation. The fuel rods were subjected to a series of preconditioning power cycles of less than 30 kW/m. Rod powers were then increased to 68 kW/m at a coolant mass flux of 4900 kg/s-m/sup 2/. After one hour at 68 kW/m, a power-cooling-mismatch sequence was initiated by a flow reduction at constant power. At a flow of 2550 kg/s-m/sup 2/, the onset of film boiling occurred on one rod, Rod IE-011. An additional flow reduction to 2245 kg/s-m/sup 2/ caused the onset of film boiling on the remaining three rods. Data are presented on the behavior of fuel rods during quasiequilibrium and during film boiling operation. The effects of initial gap size, cladding irradiation, rod power cycling, a rapid power increase, and sustained film boiling are discussed. These discussions are based on measured test data, preliminary postirradiation examination results, and comparisons of results with FRAP-T3 computer model calculations.

  16. Integrated leak rate test results of JOYO reactor containment vessel

    International Nuclear Information System (INIS)

    Tamura, M.; Endo, J.

    1982-02-01

    Integrated leak rate tests of JOYO after the reactor coolant system had been filled with sodium have been performed two times since 1978 (February 1978 and December 1979). The tests were conducted with the in-containment sodium systems, primary argon cover gas system and air conditioning systems operating. Both the absolute pressure method and the reference chamber method were employed during the test. The results of both tests confirmed the functioning of the containment vessel, and leak rate limits were satisfied. In Addition, the adequancy of the test instrumentation system and the test method was demonstrated. Finally the plant conditions required to maintain reasonable accuracy for the leak rate testing of LMFBR were established. In this paper, the test conditions and the test results are described. (author)

  17. INTRODUCTION Childhood blindness is increasingly becoming a ...

    African Journals Online (AJOL)

    number of blind years resulting from blindness in children is also equal to the number of blind years due to age related cataract.10 The burden of disability in terms of blind years in these children represents a major. CAUSES OF BLINDNESS AND VISUAL IMPAIRMENT AT THE SCHOOL FOR THE. BLIND OWO, NIGERIA.

  18. Interim Results of a Multicenter Trial with the New Electronic Subretinal Implant Alpha AMS in 15 Patients Blind from Inherited Retinal Degenerations.

    Science.gov (United States)

    Stingl, Katarina; Schippert, Ruth; Bartz-Schmidt, Karl U; Besch, Dorothea; Cottriall, Charles L; Edwards, Thomas L; Gekeler, Florian; Greppmaier, Udo; Kiel, Katja; Koitschev, Assen; Kühlewein, Laura; MacLaren, Robert E; Ramsden, James D; Roider, Johann; Rothermel, Albrecht; Sachs, Helmut; Schröder, Greta S; Tode, Jan; Troelenberg, Nicole; Zrenner, Eberhart

    2017-01-01

    Purpose: We assessed the safety and efficacy of a technically advanced subretinal electronic implant, RETINA IMPLANT Alpha AMS, in end stage retinal degeneration in an interim analysis of two ongoing prospective clinical trials. The purpose of this article is to describe the interim functional results (efficacy). Methods: The subretinal visual prosthesis RETINA IMPLANT Alpha AMS (Retina Implant AG, Reutlingen, Germany) was implanted in 15 blind patients with hereditary retinal degenerations at four study sites with a follow-up period of 12 months (www.clinicaltrials.gov NCT01024803 and NCT02720640). Functional outcome measures included (1) screen-based standardized 2- or 4-alternative forced-choice (AFC) tests of light perception, light localization, grating detection (basic grating acuity (BaGA) test), and Landolt C-rings; (2) gray level discrimination; (3) performance during activities of daily living (ADL-table tasks). Results: Implant-mediated light perception was observed in 13/15 patients. During the observation period implant mediated localization of visual targets was possible in 13/15 patients. Correct grating detection was achieved for spatial frequencies of 0.1 cpd (cycles per degree) in 4/15; 0.33 cpd in 3/15; 0.66 cpd in 2/15; 1.0 cpd in 2/15 and 3.3 cpd in 1/15 patients. In two patients visual acuity (VA) assessed with Landolt C- rings was 20/546 and 20/1111. Of 6 possible gray levels on average 4.6 ± 0.8 (mean ± SD, n = 10) were discerned. Improvements (power ON vs. OFF) of ADL table tasks were measured in 13/15 patients. Overall, results were stable during the observation period. Serious adverse events (SAEs) were reported in 4 patients: 2 movements of the implant, readjusted in a second surgery; 4 conjunctival erosion/dehiscence, successfully treated; 1 pain event around the coil, successfully treated; 1 partial reduction of silicone oil tamponade leading to distorted vision (silicon oil successfully refilled). The majority of adverse events (AEs

  19. Interim Results of a Multicenter Trial with the New Electronic Subretinal Implant Alpha AMS in 15 Patients Blind from Inherited Retinal Degenerations

    Directory of Open Access Journals (Sweden)

    Katarina Stingl

    2017-08-01

    Full Text Available Purpose: We assessed the safety and efficacy of a technically advanced subretinal electronic implant, RETINA IMPLANT Alpha AMS, in end stage retinal degeneration in an interim analysis of two ongoing prospective clinical trials. The purpose of this article is to describe the interim functional results (efficacy.Methods: The subretinal visual prosthesis RETINA IMPLANT Alpha AMS (Retina Implant AG, Reutlingen, Germany was implanted in 15 blind patients with hereditary retinal degenerations at four study sites with a follow-up period of 12 months (www.clinicaltrials.gov NCT01024803 and NCT02720640. Functional outcome measures included (1 screen-based standardized 2- or 4-alternative forced-choice (AFC tests of light perception, light localization, grating detection (basic grating acuity (BaGA test, and Landolt C-rings; (2 gray level discrimination; (3 performance during activities of daily living (ADL-table tasks.Results: Implant-mediated light perception was observed in 13/15 patients. During the observation period implant mediated localization of visual targets was possible in 13/15 patients. Correct grating detection was achieved for spatial frequencies of 0.1 cpd (cycles per degree in 4/15; 0.33 cpd in 3/15; 0.66 cpd in 2/15; 1.0 cpd in 2/15 and 3.3 cpd in 1/15 patients. In two patients visual acuity (VA assessed with Landolt C- rings was 20/546 and 20/1111. Of 6 possible gray levels on average 4.6 ± 0.8 (mean ± SD, n = 10 were discerned. Improvements (power ON vs. OFF of ADL table tasks were measured in 13/15 patients. Overall, results were stable during the observation period. Serious adverse events (SAEs were reported in 4 patients: 2 movements of the implant, readjusted in a second surgery; 4 conjunctival erosion/dehiscence, successfully treated; 1 pain event around the coil, successfully treated; 1 partial reduction of silicone oil tamponade leading to distorted vision (silicon oil successfully refilled. The majority of adverse events

  20. Relationship between ultrasonic pulse velocity test result and ...

    African Journals Online (AJOL)

    The third stage subjected the samples to UPV and destructive tests at the end of the following curing days: 1, 3, 7, 14, 21, 28, 56 and 90 days. Ultrasonic Pulse Velocity test result showed an inverse relationship (of -0.935) with the crushed concrete compressive strength. Correlation test, multiple regression analysis, graphs ...

  1. Production Facility Prototype Blower 1000 Hour Test Results II

    Energy Technology Data Exchange (ETDEWEB)

    Wass, Alexander Joseph [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Woloshun, Keith Albert [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Dale, Gregory E. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Dalmas, Dale Allen [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Romero, Frank Patrick [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2018-01-08

    Long duration tests of the Aerzen GM 12.4 roots style blower in a closed loop configuration provides valuable data and lessons learned for long-term operation at the Mo-99 production facility. The blower was operated in a closed loop configuration with the flow conditions anticipated in plant operation with a Mo-100 target inline. The additional thermal energy generated from beam heating of the Mo-100 disks were not included in these tests. Five 1000 hour tests have been completed since the first test was performed in January of 2016. All five 1000 hour tests have proven successful in exposing preventable issues related to oil and helium leaks. All blower tests to this date have resulted in stable blower performance and consistency. A summary of the results for each test, including a review of the first and second tests, are included in this report.

  2. Hawaiian Electric Advanced Inverter Test Plan - Result Summary

    Energy Technology Data Exchange (ETDEWEB)

    Hoke, Anderson; Nelson, Austin; Prabakar, Kumaraguru; Nagarajan, Adarsh

    2016-10-14

    This presentation is intended to share the results of lab testing of five PV inverters with the Hawaiian Electric Companies and other stakeholders and interested parties. The tests included baseline testing of advanced inverter grid support functions, as well as distribution circuit-level tests to examine the impact of the PV inverters on simulated distribution feeders using power hardware-in-the-loop (PHIL) techniques. hardware-in-the-loop (PHIL) techniques.

  3. Therapy for acute nonpurulent rhinosinusitis with cineole: results of a double-blind, randomized, placebo-controlled trial.

    Science.gov (United States)

    Kehrl, Wolfgang; Sonnemann, Uwe; Dethlefsen, Uwe

    2004-04-01

    Nonpurulent rhinosinusitis can be treated successfully with cineole. Prospective, randomized, double-blinded, placebo-controlled study. We compared efficacy and safety of cineole capsules with placebo capsules in 152 patients with acute rhinosinusitis (76 patients in each treatment group). The dosage of the active ingredient was two 100-mg capsules of cineole three times daily. The primary end point was the reduction of a defined symptoms-sum-score based on symptoms and signs comparing baseline therapy difference from the beginning to the end of the 7-day treatment. All randomly selected patients were assigned to the intention-to-treat-population. At the beginning, the mean symptoms-sum-score was 15.6 in both treatment groups. The mean values for the symptoms-sum-scores in the cineole group were 6.9 +/- 2.9 after 4 days and 3.0 +/- 2.8 after 7 days, and in the placebo group, 12.2 +/- 2.5 after 4 days and 9.2 +/- 3.0 after 7 days. The differences between both groups were clinically relevant and statistically significant after 4 and 7 days. The result for the primary end point was validated by the amelioration of the following secondary end points: headache on bending, frontal headache, sensitivity of pressure points of trigeminal nerve, impairment of general condition, nasal obstruction, and rhinological secretion. Mild side effects, possibly associated with medication, were observed in two patients as heartburn and exanthema after treatment with cineole. In patients with acute nonpurulent rhinosinusitis, timely treatment with cineole is effective and safe before antibiotics are indicated.

  4. Are reviewers suggested by authors as good as those chosen by editors? Results of a rater-blinded, retrospective study

    Directory of Open Access Journals (Sweden)

    Parkin Emma C

    2006-05-01

    Full Text Available Abstract Background BioMed Central (BMC requires authors to suggest four reviewers when making a submission. Editors searching for reviewers use these suggestions as a source. The review process of the medical journals in the BMC series is open – authors and reviewers know each other's identity – although reviewers can make confidential comments to the editor. Reviews are published alongside accepted articles so readers may see the reviewers' names and recommendations. Our objective was to compare the performance of author-nominated reviewers (ANR with that of editor-chosen reviewers (ECR in terms of review quality and recommendations about submissions in an online-only medical journal. Methods Pairs of reviews from 100 consecutive submissions to medical journals in the BMC series (with one author-nominated and one editor-chosen reviewer and a final decision were assessed by two raters, blinded to reviewer type, using a validated review quality instrument (RQI which rates 7 items on 5-point Likert scales. The raters discussed their ratings after the first 20 pairs (keeping reviewer type masked and resolved major discrepancies in scoring and interpretation to improve inter-rater reliability. Reviewers' recommendations were also compared. Results Reviewer source had no impact on review quality (mean RQI score (± SD 2.24 ± 0.55 for ANR, 2.34 ± 0.54 for ECR or tone (mean scores on additional question 2.72 ANR vs 2.82 ECR (maximum score = 5 in both cases. However author-nominated reviewers were significantly more likely to recommend acceptance (47 vs 35 and less likely to recommend rejection (10 vs 23 than editor-chosen reviewers after initial review (p Conclusion Author-nominated reviewers produced reviews of similar quality to editor-chosen reviewers but were more likely to recommend acceptance during the initial stages of peer review.

  5. Lactotripeptides Show No Effect on Human Blood Pressure: Results from a double-blind randomized controlled trial

    NARCIS (Netherlands)

    Engberink, M.F.; Schouten, E.G.; Kok, F.J.; Mierlo, van L.A.J.; Brouwer, I.A.; Geleijnse, J.M.

    2008-01-01

    Milk-derived peptides with ACE-inhibiting properties may have antihypertensive effects in humans. We conducted a randomized double-blind placebo-controlled trial to examine the blood pressure lowering potential of 2 ACE-inhibiting lactotripeptides, ie, Isoleucine-Proline-Proline and

  6. Lactotripeptides show no effect on human blood pressure : Results from a double-blind randomized controlled trial

    NARCIS (Netherlands)

    Engberink, Mariëlle F; Schouten, Evert G.; Kok, Frans J; Van Mierlo, Linda A J; Brouwer, Ingeborg A.; Geleijnse, Johanna M

    Milk-derived peptides with ACE-inhibiting properties may have antihypertensive effects in humans. We conducted a randomized double-blind placebo-controlled trial to examine the blood pressure lowering potential of 2 ACE-inhibiting lactotripeptides, ie, Isoleucine-Proline-Proline and

  7. Adjuvant Aspirin Therapy Reduces Symptoms of Schizophrenia Spectrum Disorders : Results From a Randomized, Double-Blind, Placebo-Controlled Trial

    NARCIS (Netherlands)

    Laan, Wijnand; Grobbee, Diederick E.; Selten, Jean-Paul; Heijnen, Cobi J.; Kahn, Rene S.; Burger, Huibert

    Objective: Inflammatory processes may play a role in the pathophysiology of schizophrenia. The aim of this study was to determine the efficacy of adjuvant treatment with aspirin (acetylsalicylic acid) in schizophrenia spectrum disorders. Method: This randomized, double-blind, placebo-controlled

  8. The great environmental restoration cost estimating shootout: A blind test of three DOE cost estimating groups

    International Nuclear Information System (INIS)

    Klemen, Paul

    1992-01-01

    The cost of the Department of Energy's (DOE) Environmental Restoration (ER) Program has increased steadily over the last three years and, in the process, has drawn increasing scrutiny from Congress, the public, and government agencies such as the Office of Management and Budget and the General Accounting Office. Programmatic costs have been reviewed by many groups from within the DOE as well as from outside agencies. While cost may appear to be a universally applicable barometer of project conditions, it is actually a single dimensional manifestation of a complex set of conditions. As such, variations in cost estimates can be caused by a variety of underlying factors such as changes in scope, schedule, performing organization, economic conditions, or regulatory environment. This paper will examine the subject of cost estimates by evaluating three different cost estimates prepared for a single project including two estimates prepared by project proponents and another estimate prepared by a review team. The paper identifies the reasons for cost growth as measured by the different estimates and evaluates the ability of review estimates to measure the validity of costs. The comparative technique used to test the three cost estimates will identify the reasons for changes in the estimated cost, over time, and evaluate the ability of an independent review to correctly identify the reasons for cost growth and evaluate the reasonableness of the cost proposed by the project proponents. Recommendations are made for improved cost estimates and improved cost estimate reviews. Conclusions are reached regarding the differences in estimate results that can be attributed to differences in estimating techniques, the implications of these differences for decision makers, and circumstances that are unique to environmental cost estimating. (author)

  9. Understanding why negative genetic test results sometimes fail to reassure.

    Science.gov (United States)

    Michie, Susan; Smith, Jonathan A; Senior, Victoria; Marteau, Theresa M

    2003-06-15

    A proportion of those receiving negative results following predictive genetic testing desire future bowel screening. This is despite a negative result meaning a general population risk of 1:7500 and despite bowel screening being experienced as aversive and clinically unnecessary. This study aimed to investigate perceptions of risk, illness, and tests amongst those receiving negative results following predictive genetic testing. Interviews with nine people receiving negative genetic test results for familial adenomatous polyposis (FAP) were analyzed using the qualitative method, interpretative phenomenological analysis (IPA). Those not reassured by negative genetic test results perceived a continuing risk to themselves and to their children. Two sets of perceptions emerged that might explain this: (1). perceptions of the genetic basis of the condition (FAP). Although the condition was perceived to be genetic, genetic status was seen as transient, so a result today could not predict the future. The condition was also seen as caused by factors other than genes, so information about only one risk factor could not be reassuring. (2). Perceptions of the genetic test. There was a lack of conviction in the ability of the genetic test, based on a blood sample, to predict a disease located in the bowel. These results suggest that some individuals receiving negative test results are not reassured because of their representations of the cause of their condition and the nature of the tests they undergo. It may be that eliciting and, when appropriate, changing people's representations prior to testing may enable those receiving negative results to be more reassured about their residual risk. Copyright 2003 Wiley-Liss, Inc.

  10. Test results judgment method based on BIT faults

    Directory of Open Access Journals (Sweden)

    Wang Gang

    2015-12-01

    Full Text Available Built-in-test (BIT is responsible for equipment fault detection, so the test data correctness directly influences diagnosis results. Equipment suffers all kinds of environment stresses, such as temperature, vibration, and electromagnetic stress. As embedded testing facility, BIT also suffers from these stresses and the interferences/faults are caused, so that the test course is influenced, resulting in incredible results. Therefore it is necessary to monitor test data and judge test failures. Stress monitor and BIT self-diagnosis would redound to BIT reliability, but the existing anti-jamming researches are mainly safeguard design and signal process. This paper focuses on test results monitor and BIT equipment (BITE failure judge, and a series of improved approaches is proposed. Firstly the stress influences on components are illustrated and the effects on the diagnosis results are summarized. Secondly a composite BIT program is proposed with information integration, and a stress monitor program is given. Thirdly, based on the detailed analysis of system faults and forms of BIT results, the test sequence control method is proposed. It assists BITE failure judge and reduces error probability. Finally the validation cases prove that these approaches enhance credibility.

  11. Finite Element Analysis and Test Results Comparison for the Hybrid Wing Body Center Section Test Article

    Science.gov (United States)

    Przekop, Adam; Jegley, Dawn C.; Rouse, Marshall; Lovejoy, Andrew E.

    2016-01-01

    This report documents the comparison of test measurements and predictive finite element analysis results for a hybrid wing body center section test article. The testing and analysis efforts were part of the Airframe Technology subproject within the NASA Environmentally Responsible Aviation project. Test results include full field displacement measurements obtained from digital image correlation systems and discrete strain measurements obtained using both unidirectional and rosette resistive gauges. Most significant results are presented for the critical five load cases exercised during the test. Final test to failure after inflicting severe damage to the test article is also documented. Overall, good comparison between predicted and actual behavior of the test article is found.

  12. Results of recent KROTOS FCI tests. Alumina vs. corium melts

    Energy Technology Data Exchange (ETDEWEB)

    Huhtiniemi, I.; Magallon, D.; Hohmann, H. [Commission of the European Communities, Ispra (Italy). Joint Research Center

    1998-01-01

    Recent results from KROTOS fuel-coolant interaction experiments are discussed. Five tests with alumina were performed under highly subcooled conditions, all of these tests resulted in spontaneous steam explosions. Additionally, four tests were performed at low subcooling to confirm, on one hand, the suppression of spontaneous steam explosions under such conditions and, on the other hand, that such a system is still triggerable using an external initiator. The other test parameters in these alumina tests included the melt superheat and the initial pressure. All the tests in the investigated superheat range (150 K - 750 K) produced a steam explosion and no evidence of the explosion suppression by the elevated initial pressure (in the limited range of 0.1 - 0.375 MPa) was observed in the alumina tests. The corium test series include a test with 3 kg of melt under both subcooled and near saturated conditions at ambient pressure. Two additional tests were performed with subcooled water; one test was performed at an elevated pressure of 0.2 MPa with 2.4 kg of melt and another test with 5.1 kg of melt at ambient pressure. None of these tests with corium produced a propagating energetic steam explosion. However, propagating low energy (about twice the energy of the trigger pulse) events were observed. All corium tests produced significantly higher water level swells during the mixing phase than the corresponding alumina tests. Present experimental evidence suggests that the water depletion in the mixing zone suppresses energetic steam explosions with corium melts at ambient pressure and in the present pour geometry. Processes that could produce such a difference in void generation are discussed. (author)

  13. An integral topical gel for cellulite reduction: results from a double-blind, randomized, placebo-controlled evaluation of efficacy

    Directory of Open Access Journals (Sweden)

    Dupont E

    2014-02-01

    Full Text Available Eric Dupont,1 Michel Journet,2 Marie-Laure Oula,3 Juan Gomez,1 Claude Léveillé,4 Estelle Loing,5 Diane Bilodeau6 1Immanence IDC Inc, Québec, QC, Canada; 2Clinique de Dermatologie St-Joseph, Montréal, QC, Canada; 3Evalulab Inc, Mont-Royal, QC, Canada; 4Clinique de Chirurgie Esthétique du Québec Métropolitain, Lévis, QC, Canada; 5Lucas Meyer Cosmetics, Québec, QC, Canada; 6CosmeConsult, Québec, QC, Canada Background: Cellulite is a serious cosmetic concern for most of the 90% of women affected by it. Objective: To assess the clinical efficacy of a complex integral anti-cellulite gel. Methods: This double-blind, randomized, placebo-controlled study involved 44 healthy women, aged 25–55 years. Subjects had a normal to slightly overweight body mass index and presented slight to moderate cellulite on their thighs, buttocks, and/or hips at baseline. Subjects were randomly assigned to either the treated or placebo group and accordingly applied the active product or placebo on their hips, stomach, buttocks, and thighs, twice daily for 3 months. Skin tonicity, orange-peel aspect, and stubborn cellulite were assessed at day 0, 28, 56, and 84. A self-evaluation questionnaire was completed by all volunteers. Results: At the end of the study, an average of 81% of the subjects applying the active product presented improvement in their cellulite condition versus 32% for the placebo group (all descriptors and sites combined. At day 84, skin tonicity, orange-peel appearance, and stubborn cellulite were improved in a significant manner (P<0.05 over placebo, on all studied areas. Skin tonicity improved on average by +41% for buttocks, +35% for hips, and +31% for thighs. Orange peel appearance was reduced on average by -25% for buttocks, -22% for hips, and -22% for thighs. Stubborn cellulite was reduced on average by -19% for buttocks, -24% for hips, and -22% for thighs. Circumference measurements decreased in a significant manner (P<0.05 over placebo

  14. Physical and chemical test results of electrostatic safe flooring materials

    Science.gov (United States)

    Gompf, R. H.

    1988-01-01

    This test program was initiated because a need existed at the Kennedy Space Center (KSC) to have this information readily available to the engineer who must make the choice of which electrostatic safe floor to use in a specific application. The information, however, should be of value throughout both the government and private industry in the selection of a floor covering material. Included are the test results of 18 floor covering materials which by test evaluation at KSC are considered electrostatically safe. Tests were done and/or the data compiled in the following areas: electrostatics, flammability, hypergolic compatibility, outgassing, floor type, material thickness, and available colors. Each section contains the test method used to gather the data and the test results.

  15. Commissioning and First Results from the Fermilab Cryomodule Test Stand

    Energy Technology Data Exchange (ETDEWEB)

    Harms, Elvin; et al.

    2017-05-01

    A new test stand dedicated to SRF cryomodule testing, CMTS1, has been commissioned and is now in operation at Fermilab. The first device to be cooled down and powered in this facility is the prototype 1.3 GHz cryomodule assembled at Fermilab for LCLS-II. We describe the demonstrated capabilities of CMTS1, report on steps taken during commissioning, provide an overview of first test results, and survey future plans.

  16. Sims Prototype System 2 Test Results - Engineering Analysis

    Energy Technology Data Exchange (ETDEWEB)

    None

    1978-01-01

    This report describes the testing, the problems encountered, and the results and conclusions obtained from tests performed on the IBM Prototype system 2, solar hot water system, at the Marshall space flight Center Solar Test Facility. System 2 is a liquid, non-draining solar energy system for supplying domestic hot water to singe residences. The system consists of collectors, storage tank, heat exchanger, pumps and associated plumbing and controls.

  17. RTG performance on Galileo and Ulysses and Cassini test results

    International Nuclear Information System (INIS)

    Kelly, C. Edward; Klee, Paul M.

    1997-01-01

    Power output from telemetry for the two Galileo RTGs are shown from the 1989 launch to the recent Jupiter encounter. Comparisons of predicted, measured and required performance are shown. Similar comparisons are made for the RTG on the Ulysses spacecraft which completed its planned mission in 1995. Also presented are test results from small scale thermoelectric modules and full scale converters performed for the Cassini program. The Cassini mission to Saturn is scheduled for an October 1997 launch. Small scale module test results on thermoelectric couples from the qualification and flight production runs are shown. These tests have exceeded 19,000 hours are continuing to provide increased confidence in the predicted long term performance of the Cassini RTGs. Test results are presented for full scale units both ETGs (E-6, E-7) and RTGs (F-2, F-5) along with mission power predictions. F-5, fueled in 1985, served as a spare for the Galileo and Ulysses missions and plays the same role in the Cassini program. It has successfully completed all acceptance testing. The ten years storage between thermal vacuum tests is the longest ever experienced by an RTG. The data from this test are unique in providing the effects of long term low temperature storage on power output. All ETG and RTG test results to date indicate that the power requirements of the Cassini spacecraft will be met. BOM and EOM power margins of at least five percent are predicted

  18. RTG performance on Galileo and Ulysses and Cassini test results

    International Nuclear Information System (INIS)

    Kelly, C.E.; Klee, P.M.

    1997-01-01

    Power output from telemetry for the two Galileo RTGs are shown from the 1989 launch to the recent Jupiter encounter. Comparisons of predicted, measured and required performance are shown. Similar comparisons are made for the RTG on the Ulysses spacecraft which completed its planned mission in 1995. Also presented are test results from small scale thermoelectric modules and full scale converters performed for the Cassini program. The Cassini mission to Saturn is scheduled for an October 1997 launch. Small scale module test results on thermoelectric couples from the qualification and flight production runs are shown. These tests have exceeded 19,000 hours are continuing to provide increased confidence in the predicted long term performance of the Cassini RTGs. Test results are presented for full scale units both ETGs (E-6, E-7) and RTGs (F-2, F-5) along with mission power predictions. F-5, fueled in 1985, served as a spare for the Galileo and Ulysses missions and plays the same role in the Cassini program. It has successfully completed all acceptance testing. The ten years storage between thermal vacuum tests is the longest ever experienced by an RTG. The data from this test are unique in providing the effects of long term low temperature storage on power output. All ETG and RTG test results to date indicate that the power requirements of the Cassini spacecraft will be met. BOM and EOM power margins of at least five percent are predicted. copyright 1997 American Institute of Physics

  19. Drug and alcohol testing results 2002 annual report

    Science.gov (United States)

    2005-02-01

    This the 7th annual report of the results of the FTA Drug and Alcohol Testing Program. The report summarizes the new reporting requirements introduced for calendar year 2001, the requirements of the overall drug and alcohol testing program, the resul...

  20. Usefulness of Routine Antibacterial Susceptibility Testing Results for ...

    African Journals Online (AJOL)

    The objective was to evaluate the usefulness and reliability of routine antibacterial susceptibility testing data in antibacterial resistance surveillance in Lagos Metropolis. The antibacterial susceptibility testing results of 3,961 clinical isolates of bacteria from four highly rated hospitals in Lagos metropolis were collated and ...

  1. 42 CFR 493.1281 - Standard: Comparison of test results.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 5 2010-10-01 2010-10-01 false Standard: Comparison of test results. 493.1281 Section 493.1281 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) STANDARDS AND CERTIFICATION LABORATORY REQUIREMENTS Quality System for Nonwaived Testing Analytic Systems § 493.1281 Standard:...

  2. Laboratory Test Results for the Travelling Wave Fault Location Scheme

    Directory of Open Access Journals (Sweden)

    Krzysztof Glik

    2014-03-01

    Full Text Available The article describes the travelling wave fault location algorithm for high voltage lines based on wavelet transform. The algorithm is implemented in a prototype and tested in the laboratory. The article presents the hardware and software part of a travelling wave fault locator, methodology and test results.

  3. Results of EMC market surveillance tests for UPS systems

    Energy Technology Data Exchange (ETDEWEB)

    Rajamaeki, J. [Safety Technology Authority, Helsinki (Finland)

    1997-12-31

    This paper reports the first wide electromagnetic compatibility (EMC) market surveillance project in Finland in which the uninterruptible power systems (UPS) on the Finnish market are monitored. Altogether 11 UPS units are EMC tested and the results of these tests are described in this paper. The effect of basic characters of UPS on the level of electromagnetic interference are analysed. (orig.) 3 refs.

  4. Drug and alcohol testing results 2009 annual report

    Science.gov (United States)

    2013-11-01

    This is the 15th annual report of the results of the Federal Transit Administrations (FTA) Drug and Alcohol Testing Program. This report summarizes the reporting requirements for calendar year 2009, the requirements of the overall drug and alcohol...

  5. Drug and alcohol testing results 2007 annual report

    Science.gov (United States)

    2009-05-01

    This is the 13th annual report of the results of the Federal Transit Administrations (FTA) Drug and Alcohol Testing Program. This report summarizes the reporting requirements for calendar year 2007, the requirements of the overall drug and alcohol...

  6. Drug and Alcohol Testing Results 2008 Annual Report

    Science.gov (United States)

    2010-09-01

    This is the 14th annual report of the results of the Federal Transit Administration's (FTA) Drug and Alcohol Testing : Program. This report summarizes the reporting requirements for calendar year 2008, the requirements of the overall : drug and alcoh...

  7. Drug and alcohol testing results 2006 annual report.

    Science.gov (United States)

    2008-08-01

    This is the 12th annual report of the results of the Federal Transit Administration's (FTA) Drug and Alcohol Testing Program. This report summarizes the reporting requirements for calendar year 2006, the requirements of the overall drug and alcohol t...

  8. Drug and alcohol testing results 2001 annual report

    Science.gov (United States)

    2003-12-01

    This is the sixth annual report of the results of the Federal Transit Administration's (FTA) Drug and Alcohol Testing Program. The report summarizes the new reporting requirements introduced for calendar year 2001, the requirements of the overall dru...

  9. Interim results from UO2 fuel oxidation tests in air

    International Nuclear Information System (INIS)

    Campbell, T.K.; Gilbert, E.R.; Thornhill, C.K.; White, G.D.; Piepel, G.F.; Griffin, C.W.j.

    1987-08-01

    An experimental program is being conducted at Pacific Northwest Laboratory (PNL) to extend the characterization of spent fuel oxidation in air. To characterize oxidation behavior of irradiated UO 2 , fuel oxidation tests were performed on declad light-water reactor spent fuel and nonirradited UO 2 pellets in the temperature range of 135 to 250 0 C. These tests were designed to determine the important independent variables that might affect spent fuel oxidation behavior. The data from this program, when combined with the test results from other programs, will be used to develop recommended spent fuel dry-storage temperature limits in air. This report describes interim test results. The initial PNL investigations of nonirradiated and spent fuels identified the important testing variables as temperature, fuel burnup, radiolysis of the air, fuel microstructure, and moisture in the air. Based on these initial results, a more extensive statistically designed test matrix was developed to study the effects of temperature, burnup, and moisture on the oxidation behavior of spent fuel. Oxidation tests were initiated using both boiling-water reactor and pressurized-water reactor fuels from several different reactors with burnups from 8 to 34 GWd/MTU. A 10 5 R/h gamma field was applied to the test ovens to simulate dry storage cask conditions. Nonirradiated fuel was included as a control. This report describes experimental results from the initial tests on both the spent and nonirradiated fuels and results to date on the tests in a 10 5 R/h gamma field. 33 refs., 51 figs., 6 tabs

  10. Recent test results on the ATLAS SCT detector

    International Nuclear Information System (INIS)

    Pernegger, H.

    2003-01-01

    The ATLAS Semiconductor Tracker (SCT) will be a central part of the tracking system of the ATLAS experiment. The SCT, which is currently under construction, will consist of four concentric barrels of silicon detectors as well as two silicon endcap detectors formed by nine disks each. After an overview of the SCT and the detector module layout, the paper will summarize recent test results obtained from silicon detector modules, which have been extensively tested before starting their large series production. The tests presented here cover electrical performance of individual modules, their performance after irradiation, as well as system tests in a multi-module setup

  11. Preliminary results of steel containment vessel model test

    International Nuclear Information System (INIS)

    Matsumoto, T.; Komine, K.; Arai, S.

    1997-01-01

    A high pressure test of a mixed-scaled model (1:10 in geometry and 1:4 in shell thickness) of a steel containment vessel (SCV), representing an improved boiling water reactor (BWR) Mark II containment, was conducted on December 11-12, 1996 at Sandia National Laboratories. This paper describes the preliminary results of the high pressure test. In addition, the preliminary post-test measurement data and the preliminary comparison of test data with pretest analysis predictions are also presented

  12. TF34 Quiet Nacelle nearfield acoustic test results

    Science.gov (United States)

    Coward, W. E.; Smith, E. B.; Sowers, H. D.

    1974-01-01

    The results of the nearfield acoustic tests conducted on the TF34 Quiet Nacelle are presented. The high fan noise suppression levels being sought (26 PNdB reduction in aft noise) necessitated the use of an extensive system of special nearfield acoustic instrumentation to properly evaluate the suppression achieved. The design, operation, and test results from each of these nearfield acoustic instrumentation systems are presented.

  13. Influence of diet on the results of laboratory tests

    Directory of Open Access Journals (Sweden)

    Kinga Lis

    2013-12-01

    Full Text Available Blood and urine laboratory tests are necessary to diagnose the state of the patient. These tests are also helpful in the assessment of diet and nutritional status of the organism. It is recommended that both blood and urine for laboratory tests be collected in the morning, from fasting patients after an overnight rest. These conditions are defined as the standard conditions for collection of material for laboratory testing. Before testing, patients should follow their natural diet and avoid physical exertion, night work, long-distance travel, as well as consumption of alcohol and drugs. They should also reduce the consumption of synthetic vitamins and herbal remedies and other dietary supplements. Medications should be limited to those that are absolutely necessary. All of these factors can affect the results of laboratory tests.

  14. Blind Astronomers

    Science.gov (United States)

    Hockey, Thomas A.

    2011-01-01

    The phrase "blind astronomer” is used as an allegorical oxymoron. However, there were and are blind astronomers. What of famous blind astronomers? First, it must be stated that these astronomers were not martyrs to their craft. It is a myth that astronomers blind themselves by observing the Sun. As early as France's William of Saint-Cloud (circa 1290) astronomers knew that staring at the Sun was ill-advised and avoided it. Galileo Galilei did not invent the astronomical telescope and then proceed to blind himself with one. Galileo observed the Sun near sunrise and sunset or through projection. More than two decades later he became blind, as many septuagenarians do, unrelated to their profession. Even Isaac Newton temporarily blinded himself, staring at the reflection of the Sun when he was a twentysomething. But permanent Sun-induced blindness? No, it did not happen. For instance, it was a stroke that left Scotland's James Gregory (1638-1675) blind. (You will remember the Gregorian telescope.) However, he died days later. Thus, blindness little interfered with his occupation. English Abbot Richard of Wallingford (circa 1291 - circa 1335) wrote astronomical works and designed astronomical instruments. He was also blind in one eye. Yet as he further suffered from leprosy, his blindness seems the lesser of Richard's maladies. Perhaps the most famous professionally active, blind astronomer (or almost blind astronomer) is Dominique-Francois Arago (1786-1853), director until his death of the powerful nineteenth-century Paris Observatory. I will share other _ some poignant _ examples such as: William Campbell, whose blindness drove him to suicide; Leonhard Euler, astronomy's Beethoven, who did nearly half of his life's work while almost totally blind; and Edwin Frost, who "observed” a total solar eclipse while completely sightless.

  15. Stochastic Blind Motion Deblurring

    KAUST Repository

    Xiao, Lei

    2015-05-13

    Blind motion deblurring from a single image is a highly under-constrained problem with many degenerate solutions. A good approximation of the intrinsic image can therefore only be obtained with the help of prior information in the form of (often non-convex) regularization terms for both the intrinsic image and the kernel. While the best choice of image priors is still a topic of ongoing investigation, this research is made more complicated by the fact that historically each new prior requires the development of a custom optimization method. In this paper, we develop a stochastic optimization method for blind deconvolution. Since this stochastic solver does not require the explicit computation of the gradient of the objective function and uses only efficient local evaluation of the objective, new priors can be implemented and tested very quickly. We demonstrate that this framework, in combination with different image priors produces results with PSNR values that match or exceed the results obtained by much more complex state-of-the-art blind motion deblurring algorithms.

  16. Uprated OMS Engine Status-Sea Level Testing Results

    Science.gov (United States)

    Bertolino, J. D.; Boyd, W. C.

    1990-01-01

    The current Space Shuttle Orbital Maneuvering Engine (OME) is pressure fed, utilizing storable propellants. Performance uprating of this engine, through the use of a gas generator driven turbopump to increase operating pressure, is being pursued by the NASA Johnson Space Center (JSC). Component level design, fabrication, and test activities for this engine system have been on-going since 1984. More recently, a complete engine designated the Integrated Component Test Bed (ICTB), was tested at sea level conditions by Aerojet. A description of the test hardware and results of the sea level test program are presented. These results, which include the test condition operating envelope and projected performance at altitude conditions, confirm the capability of the selected Uprated OME (UOME) configuration to meet or exceed performance and operational requirements. Engine flexibility, demonstrated through testing at two different operational mixture ratios, along with a summary of projected Space Shuttle performance enhancements using the UOME, are discussed. Planned future activities, including ICTB tests at simulated altitude conditions, and recommendations for further engine development, are also discussed.

  17. Flight Test Results of a Thermoelectric Energy Harvester for Aircraft

    Science.gov (United States)

    Samson, D.; Kluge, M.; Fuss, T.; Schmid, U.; Becker, Th.

    2012-06-01

    The idea of thermoelectric energy harvesting for low-power wireless sensor systems in aircraft and its practical implementation was recently published. The concept of using a thermoelectric generator (TEG) attached to the aircraft inner hull and a thermal storage device to create an artificial temperature gradient at the TEG during take-off and landing from the temperature changes of the fuselage has passed initial tests and is now subject to flight testing. This work presents preflight test results, e.g., vibration and temperature testing of the harvesters, the practical installation of two harvesting devices inside a test plane, and the first test flight results. Several flight cycles with different flight profiles, flight lengths, and outside temperatures have been performed. Although the influence of different flight profiles on the energy output of the harvester can be clearly observed, the results are in good agreement with expectations from numerical simulations with boundary conditions evaluated from initial climate chamber experiments. In addition, the flight test demonstrates that reliable operation of thermoelectric energy harvesting in harsh aircraft environments seems to be feasible, therefore paving the way for realization of energy-autonomous, wireless sensor networks.

  18. ExEP yield modeling tool and validation test results

    Science.gov (United States)

    Morgan, Rhonda; Turmon, Michael; Delacroix, Christian; Savransky, Dmitry; Garrett, Daniel; Lowrance, Patrick; Liu, Xiang Cate; Nunez, Paul

    2017-09-01

    EXOSIMS is an open-source simulation tool for parametric modeling of the detection yield and characterization of exoplanets. EXOSIMS has been adopted by the Exoplanet Exploration Programs Standards Definition and Evaluation Team (ExSDET) as a common mechanism for comparison of exoplanet mission concept studies. To ensure trustworthiness of the tool, we developed a validation test plan that leverages the Python-language unit-test framework, utilizes integration tests for selected module interactions, and performs end-to-end crossvalidation with other yield tools. This paper presents the test methods and results, with the physics-based tests such as photometry and integration time calculation treated in detail and the functional tests treated summarily. The test case utilized a 4m unobscured telescope with an idealized coronagraph and an exoplanet population from the IPAC radial velocity (RV) exoplanet catalog. The known RV planets were set at quadrature to allow deterministic validation of the calculation of physical parameters, such as working angle, photon counts and integration time. The observing keepout region was tested by generating plots and movies of the targets and the keepout zone over a year. Although the keepout integration test required the interpretation of a user, the test revealed problems in the L2 halo orbit and the parameterization of keepout applied to some solar system bodies, which the development team was able to address. The validation testing of EXOSIMS was performed iteratively with the developers of EXOSIMS and resulted in a more robust, stable, and trustworthy tool that the exoplanet community can use to simulate exoplanet direct-detection missions from probe class, to WFIRST, up to large mission concepts such as HabEx and LUVOIR.

  19. Automated Testing Infrastructure and Result Comparison for Geodynamics Codes

    Science.gov (United States)

    Heien, E. M.; Kellogg, L. H.

    2013-12-01

    The geodynamics community uses a wide variety of codes on a wide variety of both software and hardware platforms to simulate geophysical phenomenon. These codes are generally variants of finite difference or finite element calculations involving Stokes flow or wave propagation. A significant problem is that codes of even low complexity will return different results depending on the platform due to slight differences in hardware, software, compiler, and libraries. Furthermore, changes to the codes during development may affect solutions in unexpected ways such that previously validated results are altered. The Computational Infrastructure for Geodynamics (CIG) is funded by the NSF to enhance the capabilities of the geodynamics community through software development. CIG has recently done extensive work in setting up an automated testing and result validation system based on the BaTLab system developed at the University of Wisconsin, Madison. This system uses 16 variants of Linux and Mac platforms on both 32 and 64-bit processors to test several CIG codes, and has also recently been extended to support testing on the XSEDE TACC (Texas Advanced Computing Center) Stampede cluster. In this work we overview the system design and demonstrate how automated testing and validation occurs and results are reported. We also examine several results from the system from different codes and discuss how changes in compilers and libraries affect the results. Finally we detail some result comparison tools for different types of output (scalar fields, velocity fields, seismogram data), and discuss within what margins different results can be considered equivalent.

  20. Electromagnetic results of the Japanese LCT coil's domestic test

    International Nuclear Information System (INIS)

    Nishi, Masataka; Okuno, Kiyoshi; Takahashi, Yoshikazu; Tsuji, Hiroshi; Ando, Toshinari; Shimamoto, Susumu

    1984-01-01

    The domestic test of the Japanese LCT coil was carried out in 1982. During this test, the coil was charged up to the single coil's 100% state (10.22kA, 6.4T, 106MJ) four times and experienced no quenche. at the 100% charging state, coil stability was tested by using heaters installed in the conductor. A half turn length normal zone (about 5 m) generated by heaters was spontenously disappeared in 2 second. This normalized zone included the highest magnetic field position. The transport current which gives the stable limit is extraporated to be about 12.5kA at 8T by this test result. The dump test was carried out also from the 100% charging state. At that time, about 90% of the coil's stored energy was extracted by the dump resistor and the coil was not damaged. (author)

  1. [Results of spontaneous NBT-test in influenza patients].

    Science.gov (United States)

    Nagoev, B S; Orazaev, N G

    2000-01-01

    Assessment of leukocyte activity with spontaneous NBT-test in influenza patients regarding the disease stage, severity, complication and concomitant diseases. 107 influenza patients aged 16-84 years were studied. 70 patients had no complications, 11 patients had early influenzal pneumonia, 26 patients had late viral-bacterial infection. Chronic concomitant diseases were diagnosed in 23 cases. Cytochemical examination of leukocyte activity was made in all the patients using spontaneous NBT-test. In mild influenza NBT-test results were within upper limits of normal value. In alleviation of the symptoms NBT-test parameters were low. In early influenzal and viral-bacterial pneumonia leukocyte activity was high and lowered to normal in late convalescence. Parameters of spontaneous NBT-test in influenzal patients were elevated depending on influenza stage, severity and complications. This fact is of differential-diagnostic importance.

  2. Postprandial effects of dark chocolate on portal hypertension in patients with cirrhosis: results of a phase 2, double-blind, randomized controlled trial.

    Science.gov (United States)

    De Gottardi, Andrea; Berzigotti, Annalisa; Seijo, Susana; D'Amico, Mario; Thormann, Wolfgang; Abraldes, Juan G; García-Pagán, Juan Carlos; Bosch, Jaime

    2012-09-01

    In cirrhosis, hepatic endothelial dysfunction as a result of oxidative stress contributes to the postprandial increase in hepatic venous pressure gradient (HVPG). We aimed at testing the hypothesis that dark chocolate, which holds potent antioxidant properties, might attenuate the postprandial increase in HVPG in patients with cirrhosis. In this phase 2, double-blind, controlled study, 22 cirrhotic patients referred for HVPG measurement were included and randomly assigned to receive a liquid meal containing either dark chocolate (active treatment; 85% cocoa, 0.55 g/kg body wt; n = 11) or isocaloric amounts of white chocolate (devoid of cocoa flavonoids; control subjects; n = 11). HVPG, arterial pressure, portal blood flow, serum flavonoids (catechin and epicatechin), and nitric oxide were measured at baseline and 30 min after meal administration. The main outcome measure was the change in HVPG 30 min after the test meal. Postprandial hyperemia was accompanied by a marked increase in HVPG in the white-chocolate group (16.0 ± 4.7-19.7 ± 4.1 mm Hg or +26.4 ± 12.7%; P chocolate group (16.9 ± 2.9-18.7 ± 3.5 mm Hg or +11.5 ± 15.9%; P = 0.02 compared with white chocolate). Portal blood flow increased similarly after meals containing dark or white chocolate (median increase: 32% compared with 39%). Plasma flavonoids increased 15-50-fold after dark chocolate consumption. Dark but not white chocolate induced a mild increase in arterial pressure (+8.8 ± 8.8% compared with -0.3 ± 4.9%; P = 0.002). In patients with cirrhosis, dark chocolate blunted the postprandial increase in HVPG by improving flow-mediated hepatic vasorelaxation and ameliorated systemic hypotension. This trial was registered at clinicaltrials.gov as NCT01408966.

  3. Steel Containment Vessel Model Test: Results and Evaluation

    Energy Technology Data Exchange (ETDEWEB)

    Costello, J.F.; Hashimote, T.; Hessheimer, M.F.; Luk, V.K.

    1999-03-01

    A high pressure test of the steel containment vessel (SCV) model was conducted on December 11-12, 1996 at Sandia National Laboratories, Albuquerque, NM, USA. The test model is a mixed-scaled model (1:10 in geometry and 1:4 in shell thickness) of an improved Mark II boiling water reactor (BWR) containment. A concentric steel contact structure (CS), installed over the SCV model and separated at a nominally uniform distance from it, provided a simplified representation of a reactor shield building in the actual plant. The SCV model and contact structure were instrumented with strain gages and displacement transducers to record the deformation behavior of the SCV model during the high pressure test. This paper summarizes the conduct and the results of the high pressure test and discusses the posttest metallurgical evaluation results on specimens removed from the SCV model.

  4. Tensile and fracture toughness test results of neutron irradiated beryllium

    Energy Technology Data Exchange (ETDEWEB)

    Chaouadi, R.; Moons, F.; Puzzolante, J.L. [Centre d`Etude de l`Energie Nucleaire, Mol (Belgium)

    1998-01-01

    Tensile and fracture toughness test results of four Beryllium grades are reported here. The flow and fracture properties are investigated by using small size tensile and round compact tension specimens. Irradiation was performed at the BR2 material testing reactor which allows various temperature and irradiation conditions. The fast neutron fluence (>1 MeV) ranges between 0.65 and 2.45 10{sup 21} n/cm{sup 2}. In the meantime, un-irradiated specimens were aged at the irradiation temperatures to separate if any the effect of temperature from irradiation damage. Test results are analyzed and discussed, in particular in terms of the effects of material grade, test temperature, thermal ageing and neutron irradiation. (author)

  5. COMPARISON OF RESULTS OF THERMAL TESTS OF BALCONY DOORS

    Directory of Open Access Journals (Sweden)

    Golubev Stanislav Sergeevich

    2012-10-01

    Full Text Available Results of thermal tests of balcony doors are presented in the article. In the course of the research project, two types of doors were tested. The first type represents a PVC frame door (width 82 mm; it has a triple glazing (4K-16Ar-4-16Ar-K4; its blank part represents a polystyrene sandwich panel (width 40 mm. The second type represents a PVC frame door (width 82 mm, that has a triple glazing (4K-16Ar-4-16Ar-K4 and composite PVC panels. The testing procedure and processing results are described in the article. The test has demonstrated that the thermal resistance value of the balcony door of the first type exceeds the thermal resistance value of the balcony door of the second type.

  6. Test Beam Results of a 3D Diamond Detector

    CERN Document Server

    Dunser, Marc

    2015-01-01

    3D pixel technology has been used successfully in the past with silicon detectors for tracking applications. Recently, a first prototype of the same 3D technology has been produced on a chemical vapour deposited single-crystal diamond sensor. This device has been subsequently tested in a beam test at CERN’s SPS accelerator in a beam of 120 GeV protons. Details on the production and results of testbeam data are presented.

  7. First Test Results of the 4-ROD Crab Cavity

    CERN Document Server

    Ambattu, P; Burt, G; Calaga, R; Capatina, O; Calatroni, S; Ciapala, E; Doherty, D; Ferreira, L; Jensen, E; Hall, B; Lingwood, C; Maesen, P; Mongelluzzo, A; Renaglia, T; Therasse, M

    2013-01-01

    The first compact prototype crab cavity with the 4rod geometry has undergone surface treatment and cold testing. Due to the complex geometry and unique fabrication procedure, RF validation of the field at beyond the nominal operating voltage at a sufficiently high Q0 is an important pre-requisite. Preliminary results of the first cold tests are presented along with cavity performance at different stages of the cavity processing is described.

  8. Improved PFB operations - 400-hour turbine test results

    Science.gov (United States)

    Rollbuhler, R. J.; Benford, S. M.; Zellars, G. R.

    1980-04-01

    The paper deals with a 400-hr small turbine test in the effluent of a pressurized fluidized bed (PFB) at an average temperature of 770 C, an average relative gas velocity of 300 m/sec, and average solid loadings of 200 ppm. Consideration is given to combustion parameters and operating procedure as well as to the turbine system and turbine test operating procedures. Emphasis is placed on erosion/corrosion results.

  9. Results of initial nuclear tests on LWBR (LWBR Development Program)

    International Nuclear Information System (INIS)

    Sarber, W.K.

    1979-06-01

    This report presents and discusses the results of physics tests performed at beginning of life on the Light Water Breeder Reactor (LWBR). These tests have confirmed that movable seed assembly critical positions and reactivity worths, temperature coefficients, xenon transient characteristics, core symmetry, and core shutdown are within the range of values used in the design of the LWBR and its reactor protection analysis. Measured core physics parameters were found to be in good agreement with the calculated values

  10. Construction details and test results from RHIC sextupoles

    International Nuclear Information System (INIS)

    Lindner, M.; Anerella, M.; Ganetis, G.

    1993-01-01

    Four 8 cm aperture sextupoles have been built at BNL to verify the magnetic performance of this magnet in the RHIC installation. Two significantly different mechanical configurations have been designed, and two magnets of each design have been built, and successfully tested, and have exceeded the required minimum quench current by a substantial margin. This report describes the assembly details of the second configuration, which is the final production configuration. In addition the first industry built production sextupole has been delivered and tested. This report presents the results of quench tests on all 5 magnets and field measurements on the first production sextupole

  11. Physical separations soil washing system cold test results

    Energy Technology Data Exchange (ETDEWEB)

    McGuire, J.P.

    1993-07-28

    This test summary describes the objectives, methodology, and results of a physical separations soil-washing system setup and shakedown test using uncontaminated soil. The test is being conducted in preparation for a treatability test to be conducted in the North Pond of the 300-FF-1 Operable Unit. It will be used to assess the feasibility of using a physical separations process to reduce the volume of contaminated soils in the 300-FF-1 Operable Unit. The test is described in DOE-RL (1993). The setup test was conducted at an uncontrolled area located approximately 3.2 km northwest of the 300-FF-1 Operable Unit. The material processed was free of contamination. The physical separation equipment to be used in the test was transferred to the US Department of Energy (DOE) by the US Environmental Protection Agency (EPA) Risk Reduction Engineering Laboratory. On May 13, 1993, soil-washing equipment was moved to the cold test location. Design assistance and recommendation for operation was provided by the EPA.

  12. Polygraphy and Functional Magnetic Resonance Imaging in Lie Detection: A Controlled Blind Comparison Using the Concealed Information Test.

    Science.gov (United States)

    Langleben, Daniel D; Hakun, Jonathan G; Seelig, David; Wang, An-Li; Ruparel, Kosha; Bilker, Warren B; Gur, Ruben C

    2016-10-01

    Intentional deception is a common act that often has detrimental social, legal, and clinical implications. In the last decade, brain activation patterns associated with deception have been mapped with functional magnetic resonance imaging (fMRI), significantly expanding our theoretical understanding of the phenomenon. However, despite substantial criticism, polygraphy remains the only biological method of lie detection in practical use today. We conducted a blind, prospective, and controlled within-subjects study to compare the accuracy of fMRI and polygraphy in the detection of concealed information. Data were collected between July 2008 and August 2009. Participants (N = 28) secretly wrote down a number between 3 and 8 on a slip of paper and were questioned about what number they wrote during consecutive and counterbalanced fMRI and polygraphy sessions. The Concealed Information Test (CIT) paradigm was used to evoke deceptive responses about the concealed number. Each participant's preprocessed fMRI images and 5-channel polygraph data were independently evaluated by 3 fMRI and 3 polygraph experts, who made an independent determination of the number the participant wrote down and concealed. Using a logistic regression, we found that fMRI experts were 24% more likely (relative risk = 1.24, P lie detection also deserves new consideration. © Copyright 2016 Physicians Postgraduate Press, Inc.

  13. Botulinum toxin type A-a novel treatment for provoked vestibulodynia? Results from a randomized, placebo controlled, double blinded study

    DEFF Research Database (Denmark)

    Petersen, Christina Damsted; Giraldi, Annamaria; Lundvall, Lene

    2009-01-01

    INTRODUCTION: Vestibulodynia is an increasingly recognized problem among women and is often difficult to treat. AIM: This randomized, double blinded, placebo-controlled study aimed to evaluate the efficacy of Botox in the treatment of vestibulodynia. METHODS: Sixty-four women were randomized to r...... follow up. Women with vestibulodynia have difficulty with sexual function and present with sexual distress, which has to be addressed in conjunction with pain to eliminate the disorder.......INTRODUCTION: Vestibulodynia is an increasingly recognized problem among women and is often difficult to treat. AIM: This randomized, double blinded, placebo-controlled study aimed to evaluate the efficacy of Botox in the treatment of vestibulodynia. METHODS: Sixty-four women were randomized...... to receive Botox (N = 32) or saline placebo (N = 32). Botulinum toxin A (20 I.E.) diluted in 0.5 mL saline or 0.5 mL saline was injected in the musculus bulbospongiosus at baseline. MAIN OUTCOME MEASURES: Pain was measured monthly on a visual analog scale (VAS) Likert scale. Sexual function was measured...

  14. Patch Test Results in Patients with Allergic Contact Dermatitis / Mucositis

    Directory of Open Access Journals (Sweden)

    Özlem Su

    2008-05-01

    Full Text Available Background and Design: The aims of our study were to determine the frequency of positive patch reactions and the most common allergens in patients with allergic contact dermatitis (ACD and/or mucositis(M who underwent with T.R.U.E. “Thin-layer Rapid-Use Epicutaneous” test and evaluate supplemantal series used with T.R.U.E. test effect on patch test results.Material and Method: In this study 161 ACD, 5 ACM, 1 ACD and ACM were enrolled. While 139 of all patients were patch tested with T.R.U.E. test alone,out of 28 patients were tested for T.R.U.E. test and also with supplemental series that included textile colours (9 of tested patients, plastic and glues (9, dental screening (6, backery (2, cosmetic (1 and plastic and glues and dental screening (1. Supplemental series were chosen according to patient’s occupation and clinic presentation. The data from our patients were analyzed as percentage. The relationship between contact sensitization and atopic status was evaluated with Yate’s correlation x2 test.Results: Eighty-six male, 81 female were taken into this study. The median age was 36.5.While 25.9% of 139 patients tested with T.R.U.E. test alone,46.4% of 28 patients applied supplemental series in addition to T.R.U.E. test showed positive reaction to one or more allergens. The most common allergens were nickel sulphate (14.4%, potassium dichromate (4.8%, fragrance mix (2.9% and colophony (2.9%. The most common supplemental allergens were octil gallat (50% in bakery and copper sulphate, goldsodiumthiosulphate (42.8% in dental screening. Positive patch reactions were detected 83.3% in 6 patients with AKM, 80% of these positive reactions was againts dental screening. The rate of contact sensitization between atopics and non-atopics was not significant (p>0.05. Conclusion: We suggest in presence of mucositis and/or occupational dermatoses using supplemental series in addition to T.R.U.E. test would be more beneficial in identifing the

  15. Small-Scale Spray Releases: Initial Aerosol Test Results

    Energy Technology Data Exchange (ETDEWEB)

    Mahoney, Lenna A.; Gauglitz, Phillip A.; Kimura, Marcia L.; Brown, Garrett N.; Kurath, Dean E.; Buchmiller, William C.; Smith, Dennese M.; Blanchard, Jeremy; Song, Chen; Daniel, Richard C.; Wells, Beric E.; Tran, Diana N.; Burns, Carolyn A.

    2013-05-29

    One of the events postulated in the hazard analysis at the Waste Treatment and Immobilization Plant (WTP) and other U.S. Department of Energy (DOE) nuclear facilities is a breach in process piping that produces aerosols with droplet sizes in the respirable range. The current approach for predicting the size and concentration of aerosols produced in a spray leak involves extrapolating from correlations reported in the literature. These correlations are based on results obtained from small engineered spray nozzles using pure liquids with Newtonian fluid behavior. The narrow ranges of physical properties on which the correlations are based do not cover the wide range of slurries and viscous materials that will be processed in the WTP and across processing facilities in the DOE complex. Two key technical areas were identified where testing results were needed to improve the technical basis by reducing the uncertainty due to extrapolating existing literature results. The first technical need was to quantify the role of slurry particles in small breaches where the slurry particles may plug and result in substantially reduced, or even negligible, respirable fraction formed by high-pressure sprays. The second technical need was to determine the aerosol droplet size distribution and volume from prototypic breaches and fluids, specifically including sprays from larger breaches with slurries where data from the literature are scarce. To address these technical areas, small- and large-scale test stands were constructed and operated with simulants to determine aerosol release fractions and net generation rates from a range of breach sizes and geometries. The properties of the simulants represented the range of properties expected in the WTP process streams and included water, sodium salt solutions, slurries containing boehmite or gibbsite, and a hazardous chemical simulant. The effect of antifoam agents was assessed with most of the simulants. Orifices included round holes and

  16. Evaluation of the screening test results before marriage

    Directory of Open Access Journals (Sweden)

    Süleyman Durmaz

    2011-09-01

    Full Text Available Objectives: Human immunodeficiency virus (HIV, Hepatitis B and Hepatitis C viruses and Treponema pallidum are parenterally and sexually transmitted infection agents. Screening test is made before marriage to pre-marital couples legally under the relevant legislation and legal procedures in our country; applicants are evaluated in terms of sexually transmitted diseases. The aim of this study is to evaluate pre-marital test results for HBsAg, anti-HCV, anti-HIV I/II and Treponema pallidum.Materials and methods: To make screening test before marriage, randomized 117 patients who were applied to Kızıltepe General Hospital of Infectious Diseases and Clinical Microbiology, were included in this study between January 2011 and March 2011. Of these patients, 64 were women (average age 24.7±5.7, and 55 were males (mean age 24.7±4.7. HBsAg, anti-HCV and anti-HIV I/II tests of the patients were studied by macro-ELISA device (ECIQ Vitros, Ortho Clinical Diagnostics, USA, screening of anti-Treponema pallidum IgG, IgA and IgM antibodies were studied by immunochromatographic rapid test (syphilis syphilis 3.0, Standard Diagnostics, inc. Korea.Results: Of the 119 patients, five patients (4.2% were positive for HBsAg (3 male and 2 female. Anti-HCV, anti-HIV I/II and anti-Treponema pallidum antibodies were negative in all patients.Conclusion: HBsAg test result which was obtained in present study has been found consistent with HBsAg positivity rate in our region. As a result of screening test that was done before marriage will continue to believe that the increased importance of the prevention of sexually transmitted diseases. J Clin Exp Invest 2011; 2 (3: 292-294.

  17. Healthy Efficient New Gas Homes (HENGH) Pilot Test Results

    Energy Technology Data Exchange (ETDEWEB)

    Chan, Wanyu R. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Maddalena, Randy L [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Stratton, Chris [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Hotchi, Toshifumi [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Singer, Brett C. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Walker, Iain S. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Sherman, Max H. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2016-05-01

    The Healthy Efficient New Gas Homes (HENGH) is a field study that will collect data on ventilation systems and indoor air quality (IAQ) in new California homes that were built to 2008 Title 24 standards. A pilot test was performed to help inform the most time and cost effective approaches to measuring IAQ in the 100 test homes that will be recruited for this study. Two occupied, single-family detached homes built to 2008 Title 24 participated in the pilot test. One of the test homes uses exhaust-only ventilation provided by a continuous exhaust fan in the laundry room. The other home uses supply air for ventilation. Measurements of IAQ were collected for two weeks. Time-resolved concentrations of particulate matter (PM), nitrogen dioxide (NO2), carbon dioxide (CO2), carbon monoxide (CO), and formaldehyde were measured. Measurements of IAQ also included time-integrated concentrations of volatile organic compounds (VOCs), volatile aldehydes, and NO2. Three perfluorocarbon tracers (PFTs) were used to estimate the dilution rate of an indoor emitted air contaminant in the two pilot test homes. Diagnostic tests were performed to measure envelope air leakage, duct leakage, and airflow of range hood, exhaust fans, and clothes dryer vent when accessible. Occupant activities, such as cooking, use of range hood and exhaust fans, were monitored using various data loggers. This document describes results of the pilot test.

  18. Results of assembly test of HTTR reactor internals

    International Nuclear Information System (INIS)

    Maruyama, S.; Saikusa, A.; Shiozawa, S.; Tsuji, N.; Miki, T.

    1996-01-01

    The assembly test of the HTTR actual reactor internals had been carried out at the works, prior to their installation in the actual reactor pressure vessel(RPV) at the construction site. The assembly test consists of several items such as examining fabricating precision of each component and alignment of piled-up structures, measuring circumferential coolant velocity profile in the passage between the simulated RPV and the reactor internals as well as under the support plates, measuring by-pass flow rate through gaps between the reactor internals, and measuring the binding force of the core restraint mechanism. Results of the test showed good performance of the HTTR reactor internals. Installation of the reactor internals in the actual RPV was started at the construction site of HTTR in April, 1995. In the installation process, main items of the assembly test at the works were repeated to investigate the reproducibility of installation. (author). 5 refs, 11 figs

  19. Results from the 1999 Beam Test of a Preshower Prototype

    CERN Document Server

    Aspell, Paul; Bloch, Philippe; Bourotte, Jean; Domeniconi, Jacques; Peisert, Anna; Evangelou, Ioannis; Kloukinas, Kostas; Kyriakis, Aristotelis; Loos, Robert; Loukas, Demetrios; Mousa, Jehad; Peron, Franck; Reynaud, Serge; Sirunyan, Albert M; Tournefier, Edwige; Van Hove, Alain; Zamiatin, Nikolai

    2000-01-01

    At the end of June 1999 a test of a preshower prototype, equipped with real-size detectors and LHC-style electronics, was tested in the H4 beam at CERN in front of a matrix of "Endcap" crystals. Data were taken with a variety of incident electron energies, and three angles of incidence ( to simulate different regions of the CMS endcaps). The prototype functioned well, with a very small startup period and operated successfully for the duration of the test ( ~ 1 week) without intervention. Good agreement has been found between data and a GEANT-3 based simulation, and the absolute results are promising. Plans are presented for a further test of the prototype in 2000 in the H2 beam inside the 3T magnet.

  20. LWR aerosol containment experiments (LACE) program and initial test results

    International Nuclear Information System (INIS)

    Muhlestein, L.D.; Hilliard, R.K.; Bloom, G.R.; McCormack, J.D.; Rahn, F.J.

    1985-01-01

    The LWR aerosol containment experiments (LACE) program is described. The LACE program is being performed at the Hanford Engineer Development Laboratory (operated by Westinghouse Hanford Company) and the initial tests are sponsored by EPRI. The objectives of the LACE program are: to demonstrate, at large-scale, inherent radioactive aerosol retention behavior for postulated high consequence LWR accident situations; and to provide a data base to be used for aerosol behavior . Test results from the first phase of the LACE program are presented and discussed. Three large-scale scoping tests, simulating a containment bypass accident sequence, demonstrated the extent of agglomeration and deposition of aerosols occurring in the pipe pathway and vented auxiliary building under realistic accident conditions. Parameters varied during the scoping tests were aerosol type and steam condensation

  1. Selected Test Results from the Encell Technology Nickel Iron Battery

    Energy Technology Data Exchange (ETDEWEB)

    Ferreira, Summer Kamal Rhodes [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). Advanced Power Sources R& D; Baca, Wes Edmund [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). Advanced Power Sources R& D; Avedikian, Kristan [Encell Technology, Alachua, FL (United States)

    2014-09-01

    The performance of the Encell Nickel Iron (NiFe) battery was measured. Tests included capacity, capacity as a function of rate, capacity as a function of temperature, charge retention (28-day), efficiency, accelerated life projection, and water refill evaluation. The goal of this work was to evaluate the general performance of the Encell NiFe battery technology for stationary applications and demonstrate the chemistry's capabilities in extreme conditions. Test results have indicated that the Encell NiFe battery technology can provide power levels up to the 6C discharge rate, ampere-hour efficiency above 70%. In summary, the Encell batteries have met performance metrics established by the manufacturer. Long-term cycle tests are not included in this report. A cycle test at elevated temperature was run, funded by the manufacturer, which Encell uses to predict long-term cycling performance, and which passed their prescribed metrics.

  2. Small-Scale Spray Releases: Initial Aerosol Test Results

    Energy Technology Data Exchange (ETDEWEB)

    Mahoney, Lenna A.; Gauglitz, Phillip A.; Kimura, Marcia L.; Brown, Garrett N.; Kurath, Dean E.; Buchmiller, William C.; Smith, Dennese M.; Blanchard, Jeremy; Song, Chen; Daniel, Richard C.; Wells, Beric E.; Tran, Diana N.; Burns, Carolyn A.

    2012-11-01

    One of the events postulated in the hazard analysis at the Waste Treatment and Immobilization Plant (WTP) and other U.S. Department of Energy (DOE) nuclear facilities is a breach in process piping that produces aerosols with droplet sizes in the respirable range. The current approach for predicting the size and concentration of aerosols produced in a spray leak involves extrapolating from correlations reported in the literature. These correlations are based on results obtained from small engineered spray nozzles using pure liquids with Newtonian fluid behavior. The narrow ranges of physical properties on which the correlations are based do not cover the wide range of slurries and viscous materials that will be processed in the WTP and across processing facilities in the DOE complex. Two key technical areas were identified where testing results were needed to improve the technical basis by reducing the uncertainty due to extrapolating existing literature results. The first technical need was to quantify the role of slurry particles in small breaches where the slurry particles may plug and result in substantially reduced, or even negligible, respirable fraction formed by high-pressure sprays. The second technical need was to determine the aerosol droplet size distribution and volume from prototypic breaches and fluids, specifically including sprays from larger breaches with slurries where data from the literature are scarce. To address these technical areas, small- and large-scale test stands were constructed and operated with simulants to determine aerosol release fractions and generation rates from a range of breach sizes and geometries. The properties of the simulants represented the range of properties expected in the WTP process streams and included water, sodium salt solutions, slurries containing boehmite or gibbsite, and a hazardous chemical simulant. The effect of anti-foam agents was assessed with most of the simulants. Orifices included round holes and

  3. Wind tunnel test IA300 analysis and results, volume 1

    Science.gov (United States)

    Kelley, P. B.; Beaufait, W. B.; Kitchens, L. L.; Pace, J. P.

    1987-01-01

    The analysis and interpretation of wind tunnel pressure data from the Space Shuttle wind tunnel test IA300 are presented. The primary objective of the test was to determine the effects of the Space Shuttle Main Engine (SSME) and the Solid Rocket Booster (SRB) plumes on the integrated vehicle forebody pressure distributions, the elevon hinge moments, and wing loads. The results of this test will be combined with flight test results to form a new data base to be employed in the IVBC-3 airloads analysis. A secondary objective was to obtain solid plume data for correlation with the results of gaseous plume tests. Data from the power level portion was used in conjunction with flight base pressures to evaluate nominal power levels to be used during the investigation of changes in model attitude, eleveon deflection, and nozzle gimbal angle. The plume induced aerodynamic loads were developed for the Space Shuttle bases and forebody areas. A computer code was developed to integrate the pressure data. Using simplified geometrical models of the Space Shuttle elements and components, the pressure data were integrated to develop plume induced force and moments coefficients that can be combined with a power-off data base to develop a power-on data base.

  4. Guidelines to Interpret Results of Mechanical Blade Test

    International Nuclear Information System (INIS)

    Arias Vega, F.; Sanz Martin, J. C.

    1999-01-01

    This report shows the interpretation of full scale rotor blade test results and describes the engineering testing models and coefficients for any feasible rotor blade design, in order to accept and to certify any final manufactured blade as an allowable product, fit for use and working with a completely security during all the wind turbines lifetime. This work was carried out at the Wind Energy Division of the CIEMAT.DER and it is based on the authors technical experience in this field, after many years working on testing blades. Also, this paper contains results of the European wind turbine Standards II relevant to the European Project: JOULE III R.D. where the Wind Energy Division took part as participant too. (Author)

  5. Test-beam results of a SOI pixel detector prototype

    CERN Document Server

    Bugiel, Roma; Dannheim, Dominik; Fiergolski, Adrian; Hynds, Daniel; Idzik, Marek; Kapusta, P; Kucewicz, Wojciech; Munker, Ruth Magdalena; Nurnberg, Andreas Matthias

    2018-01-01

    This paper presents the test-beam results of a monolithic pixel-detector prototype fabricated in 200 nm Silicon-On-Insulator (SOI) CMOS technology. The SOI detector was tested at the CERN SPS H6 beam line. The detector is fabricated on a 500 μm thick high-resistivity float- zone n-type (FZ-n) wafer. The pixel size is 30 μm × 30 μm and its readout uses a source- follower configuration. The test-beam data are analysed in order to compute the spatial resolution and detector efficiency. The analysis chain includes pedestal and noise calculation, cluster reconstruction, as well as alignment and η-correction for non-linear charge sharing. The results show a spatial resolution of about 4.3 μm.

  6. Results for the Brine Evaporation Bag (BEB) Brine Processing Test

    Science.gov (United States)

    Delzeit, Lance; Flynn, Michael; Fisher, John; Shaw, Hali; Kawashima, Brian; Beeler, David; Howard, Kevin

    2015-01-01

    The recent Brine Processing Test compared the NASA Forward Osmosis Brine Dewatering (FOBD), Paragon Ionomer Water Processor (IWP), UMPQUA Ultrasonic Brine Dewatering System (UBDS), and the NASA Brine Evaporation Bag (BEB). This paper reports the results of the BEB. The BEB was operated at 70 deg C and a base pressure of 12 torr. The BEB was operated in a batch mode, and processed 0.4L of brine per batch. Two different brine feeds were tested, a chromic acid-urine brine and a chromic acid-urine-hygiene mix brine. The chromic acid-urine brine, known as the ISS Alternate Pretreatment Brine, had an average processing rate of 95 mL/hr with a specific power of 5kWhr/L. The complete results of these tests will be reported within this paper.

  7. Potential for false positive HIV test results with the serial rapid HIV testing algorithm

    Directory of Open Access Journals (Sweden)

    Baveewo Steven

    2012-03-01

    Full Text Available Abstract Background Rapid HIV tests provide same-day results and are widely used in HIV testing programs in areas with limited personnel and laboratory infrastructure. The Uganda Ministry of Health currently recommends the serial rapid testing algorithm with Determine, STAT-PAK, and Uni-Gold for diagnosis of HIV infection. Using this algorithm, individuals who test positive on Determine, negative to STAT-PAK and positive to Uni-Gold are reported as HIV positive. We conducted further testing on this subgroup of samples using qualitative DNA PCR to assess the potential for false positive tests in this situation. Results Of the 3388 individuals who were tested, 984 were HIV positive on two consecutive tests, and 29 were considered positive by a tiebreaker (positive on Determine, negative on STAT-PAK, and positive on Uni-Gold. However, when the 29 samples were further tested using qualitative DNA PCR, 14 (48.2% were HIV negative. Conclusion Although this study was not primarily designed to assess the validity of rapid HIV tests and thus only a subset of the samples were retested, the findings show a potential for false positive HIV results in the subset of individuals who test positive when a tiebreaker test is used in serial testing. These findings highlight a need for confirmatory testing for this category of individuals.

  8. Effects of Teriparatide Compared with Risedronate on Recovery After Pertrochanteric Hip Fracture: Results of a Randomized, Active-Controlled, Double-Blind Clinical Trial at 26 Weeks.

    Science.gov (United States)

    Aspenberg, Per; Malouf, Jorge; Tarantino, Umberto; García-Hernández, Pedro A; Corradini, Costantino; Overgaard, Søren; Stepan, Jan J; Borris, Lars; Lespessailles, Eric; Frihagen, Frede; Papavasiliou, Kyriakos; Petto, Helmut; Caeiro, José Ramón; Marin, Fernando

    2016-11-16

    Osteoporosis drugs might affect fracture-healing. We therefore studied the effects of teriparatide in comparison with risedronate on recovery after pertrochanteric hip fractures. The study was a randomized, multicenter, active-controlled, 78-week trial comparing teriparatide (20 μg/day) with risedronate (35 mg/week) initiated within 2 weeks after fixation of a low-trauma pertrochanteric hip fracture (AO/OTA 31-A1 or 31-A2). The main inclusion criteria were a bone mineral density T-score of ≤-2.0 and 25-OH-vitamin D of ≥9.2 ng/mL. During the first 26 weeks, patients received study medication with oral or injectable placebo plus calcium and vitamin D in a double-blinded fashion. Secondary (Timed Up-and-Go [TUG] test, hip pain, Short Form [SF]-36 health status, and safety) and exploratory (radiographic outcomes and ability to walk) 26-week end points are reported. Of the 224 patients who were randomized, 171 (86 teriparatide, 85 risedronate) were included in the analysis. The mean age was 77 ± 8 years, 77% were female, and 26% had a prior history of low-trauma fracture. The teriparatide group completed the TUG test in a shorter time at 6, 12, 18, and 26 weeks (differences of -5.7, -4.4, -3.1, and -3.1 seconds, respectively; p = 0.021 for the overall difference). They also reported less pain on a visual analog scale immediately after the TUG test at 12 and 18 weeks (adjusted absolute differences of 10.6 and 11.9 mm, respectively; p teriparatide, 7; risedronate, 8), loss of reduction (teriparatide, 2; risedronate, 4), and nonunion (0 cases) were not significantly different. Mild hypercalcemia and hyperuricemia were more frequent with teriparatide. Teriparatide was associated with less pain and a shorter time to complete the TUG test between 6 and 26 weeks compared with risedronate. Other fracture-recovery outcomes were similar. The results should be interpreted with caution as these were secondary end points. Therapeutic Level II. See Instructions for Authors for

  9. Interpretation of Chemical Pathology Test Results in Paediatrics ...

    African Journals Online (AJOL)

    At any time we interprete paediatric chemical pathology test results we must take into consideration a number of factors, which are related with and restricted to paediatric patients. Such factors include the paediatric patient's age that may change from prematurity to above 18 years, and the paediatric patient's body weight ...

  10. Pattern Of Skin Prick Allergy Test Results In Enugu | Mgbor ...

    African Journals Online (AJOL)

    In this study we report on pattern of allergy prick skin test results found among atopic patients attending the department of otorhinolargngology of the University of Nigeria Teaching Hospital Enugu and Hansa Clinics, Enugu and propose ways of minimizing the exposure of the population to allergens. Material and method

  11. 49 CFR 199.109 - Review of drug testing results.

    Science.gov (United States)

    2010-10-01

    ... assistance in resolving problems with drug abuse, does not refer the covered employee to the substance abuse... person under contract to provide treatment for drug problems on behalf of the operator; (3) The sole... 49 Transportation 3 2010-10-01 2010-10-01 false Review of drug testing results. 199.109 Section...

  12. Recent results on the RIA test in IGR reactor

    International Nuclear Information System (INIS)

    Asmolov, V.; Yegorova, L.

    1997-01-01

    At the 23d WRSM meeting the data base characterizing results of VVER high burnup fuel rods tests under reactivity-initiated accident (RIA) conditions was presented. Comparison of PWR and VVER failure thresholds was given also. Additional analysis of the obtained results was being carried out during 1996. The results of analysis show that the two different failure mechanisms were observed for PWR and VVER fuel rods. Some factors which can be as the possible reasons of these differences are presented. First of them is the state of preirradiated cladding. Published test data for PWR high burnup fuel rods demonstrated that the PWR high burnup fuel rods failed at the RIA test are characterized by very high level of oxidation and hydriding for the claddings. Corresponding researches were performed at Institute of Atomic Reactors (RLAR, Dimitrovgrad, Russia) for large set of VVER high burnup fuel rods. Results of these investigations show that preirradiated commercial Zr-1%Nb claddings practically keep their initial levels of oxidation and H 2 concentration. Consequently the VVER preirradiated cladding must keep the high level of mechanical properties. The second reason leading to differences between failure mechanisms for two types of high burnup fuel rods can be the test conditions. Now such kind of analysis have been performed by two methods

  13. ATLAS Transition Radiation Tracker test-beam results

    Science.gov (United States)

    Akesson, T.; Arik, E.; Baker, K.; Baron, S.; Benjamin, D.; Bertelsen, H.; Bondarenko, V.; Bytchkov, V.; Callahan, J.; Capeans, M.; Cardiel-Sas, L.; Catinaccio, A.; Cetin, S. A.; Cwetanski, P.; Dam, M.; Danielsson, H.; Dittus, F.; Dolgoshein, B.; Dressnandt, N.; Driouichi, C.; Ebenstein, W. L.; Eerola, P.; Farthouat, P.; Fedin, O.; Froidevaux, D.; Gagnon, P.; Grichkevitch, Y.; Grigalashvili, N.; Hajduk, Z.; Hansen, P.; Kayumov, F.; Keener, P. T.; Kekelidze, G.; Khristatchev, A.; Konovalov, S.; Koudine, L.; Kovalenko, S.; Kowalski, T.; Kramarenko, V. A.; Kruger, K.; Laritchev, A.; Lichard, P.; Luehring, F.; Lundberg, B.; Maleev, V.; Markina, I.; McFarlane, K.; Mialkovski, V.; Mitsou, V. A.; Mindur, B.; Morozov, S.; Munar, A.; Muraviev, S.; Nadtochy, A.; Newcomer, F. M.; Ogren, H.; Oh, S. H.; Oleshko, S.; Olszowska, J.; Passmore, S.; Patritchev, S.; Peshekhonov, V.; Petti, R.; Price, M.; Rembser, C.; Rohne, O.; Romaniouk, A.; Rust, D. R.; Ryabov, Yu.; Schegelsky, V.; Seliverstov, D.; Shin, T.; Shmeleva, A.; Smirnov, S.; Sosnovtsev, V.; Soutchkov, V.; Spiridenkov, E.; Tikhomirov, V.; Van Berg, R.; Vassilakopoulos, V.; Vassilieva, L.; Wang, C.; Williams, H. H.; Zalite, A.

    2004-04-01

    Several prototypes of the Transition Radiation Tracker for the ATLAS experiment at the LHC have been built and tested at the CERN SPS accelerator. Results from detailed studies of the straw-tube hit registration efficiency and drift-time measurements and of the pion and electron spectra without and with radiators are presented.

  14. Using soil test results to determine fertilizer applications

    Science.gov (United States)

    C. B. Davey

    2002-01-01

    Using soil test results is a very useful practice IF the sample(s) of soil are good representations of the nursery soil. The lab results can be no more accurate than the samples submitted, and IF you know the texture of the nursery soil, and IF you know which soil extractant was used by the lab, and IF you know what crop is to be grown, and IF, for trees, which species...

  15. Automated result analysis in radiographic testing of NPPs' welded joints

    International Nuclear Information System (INIS)

    Skomorokhov, A.O.; Nakhabov, A.V.; Belousov, P.A.

    2009-01-01

    The article presents development results of algorithms for automated image interpretation of NPP welded joints radiographic inspection. The developed algorithms are based on state-of-the-art pattern recognition methods. The paper covers automatic radiographic image segmentation, defects detection and their parameters evaluation issues. The developed algorithms testing results for actual radiographic images of welded joints with significant variation of defects parameters are given [ru

  16. Large-Scale Spray Releases: Initial Aerosol Test Results

    Energy Technology Data Exchange (ETDEWEB)

    Schonewill, Philip P.; Gauglitz, Phillip A.; Bontha, Jagannadha R.; Daniel, Richard C.; Kurath, Dean E.; Adkins, Harold E.; Billing, Justin M.; Burns, Carolyn A.; Davis, James M.; Enderlin, Carl W.; Fischer, Christopher M.; Jenks, Jeromy WJ; Lukins, Craig D.; MacFarlan, Paul J.; Shutthanandan, Janani I.; Smith, Dennese M.

    2012-12-01

    One of the events postulated in the hazard analysis at the Waste Treatment and Immobilization Plant (WTP) and other U.S. Department of Energy (DOE) nuclear facilities is a breach in process piping that produces aerosols with droplet sizes in the respirable range. The current approach for predicting the size and concentration of aerosols produced in a spray leak involves extrapolating from correlations reported in the literature. These correlations are based on results obtained from small engineered spray nozzles using pure liquids with Newtonian fluid behavior. The narrow ranges of physical properties on which the correlations are based do not cover the wide range of slurries and viscous materials that will be processed in the WTP and across processing facilities in the DOE complex. Two key technical areas were identified where testing results were needed to improve the technical basis by reducing the uncertainty due to extrapolating existing literature results. The first technical need was to quantify the role of slurry particles in small breaches where the slurry particles may plug and result in substantially reduced, or even negligible, respirable fraction formed by high-pressure sprays. The second technical need was to determine the aerosol droplet size distribution and volume from prototypic breaches and fluids, specifically including sprays from larger breaches with slurries where data from the literature are scarce. To address these technical areas, small- and large-scale test stands were constructed and operated with simulants to determine aerosol release fractions and generation rates from a range of breach sizes and geometries. The properties of the simulants represented the range of properties expected in the WTP process streams and included water, sodium salt solutions, slurries containing boehmite or gibbsite, and a hazardous chemical simulant. The effect of anti-foam agents was assessed with most of the simulants. Orifices included round holes and

  17. Graphite electrode arc melter demonstration Phase 2 test results

    Energy Technology Data Exchange (ETDEWEB)

    Soelberg, N.R.; Chambers, A.G.; Anderson, G.L.; O`Connor, W.K.; Oden, L.L.; Turner, P.C.

    1996-06-01

    Several U.S. Department of Energy organizations and the U.S. Bureau of Mines have been collaboratively conducting mixed waste treatment process demonstration testing on the near full-scale graphite electrode submerged arc melter system at the Bureau`s Albany (Oregon) Research Center. An initial test series successfully demonstrated arc melter capability for treating surrogate incinerator ash of buried mixed wastes with soil. The conceptual treatment process for that test series assumed that buried waste would be retrieved and incinerated, and that the incinerator ash would be vitrified in an arc melter. This report presents results from a recently completed second series of tests, undertaken to determine the ability of the arc melter system to stably process a wide range of {open_quotes}as-received{close_quotes} heterogeneous solid mixed wastes containing high levels of organics, representative of the wastes buried and stored at the Idaho National Engineering Laboratory (INEL). The Phase 2 demonstration test results indicate that an arc melter system is capable of directly processing these wastes and could enable elimination of an up-front incineration step in the conceptual treatment process.

  18. Graphite electrode arc melter demonstration Phase 2 test results

    International Nuclear Information System (INIS)

    Soelberg, N.R.; Chambers, A.G.; Anderson, G.L.; O'Connor, W.K.; Oden, L.L.; Turner, P.C.

    1996-06-01

    Several U.S. Department of Energy organizations and the U.S. Bureau of Mines have been collaboratively conducting mixed waste treatment process demonstration testing on the near full-scale graphite electrode submerged arc melter system at the Bureau's Albany (Oregon) Research Center. An initial test series successfully demonstrated arc melter capability for treating surrogate incinerator ash of buried mixed wastes with soil. The conceptual treatment process for that test series assumed that buried waste would be retrieved and incinerated, and that the incinerator ash would be vitrified in an arc melter. This report presents results from a recently completed second series of tests, undertaken to determine the ability of the arc melter system to stably process a wide range of open-quotes as-receivedclose quotes heterogeneous solid mixed wastes containing high levels of organics, representative of the wastes buried and stored at the Idaho National Engineering Laboratory (INEL). The Phase 2 demonstration test results indicate that an arc melter system is capable of directly processing these wastes and could enable elimination of an up-front incineration step in the conceptual treatment process

  19. Space Launch System Base Heating Test: Experimental Operations & Results

    Science.gov (United States)

    Dufrene, Aaron; Mehta, Manish; MacLean, Matthew; Seaford, Mark; Holden, Michael

    2016-01-01

    NASA's Space Launch System (SLS) uses four clustered liquid rocket engines along with two solid rocket boosters. The interaction between all six rocket exhaust plumes will produce a complex and severe thermal environment in the base of the vehicle. This work focuses on a recent 2% scale, hot-fire SLS base heating test. These base heating tests are short-duration tests executed with chamber pressures near the full-scale values with gaseous hydrogen/oxygen engines and RSRMV analogous solid propellant motors. The LENS II shock tunnel/Ludwieg tube tunnel was used at or near flight duplicated conditions up to Mach 5. Model development was based on the Space Shuttle base heating tests with several improvements including doubling of the maximum chamber pressures and duplication of freestream conditions. Test methodology and conditions are presented, and base heating results from 76 runs are reported in non-dimensional form. Regions of high heating are identified and comparisons of various configuration and conditions are highlighted. Base pressure and radiometer results are also reported.

  20. Developing a flammability test system for sunglasses: results

    Science.gov (United States)

    Magri, Renan; Ventura, Liliane

    2015-03-01

    Sunglasses popularity has increased tremendously. This fact has further led to the need of certificating sunglasses accordingly to the standard NBR 15111 to protect consumers from damages and secondary hazards caused by sunglasses use. The ongoing need comes at the expense that none certification institution in Brazil performs all tests procedures required by the NBR 15111. This manuscript presents the development of a flammability test system for sunglasses and the assessments results. The equipment for testing flammability developed is made of an electrical furnace with a thermocouple and electronic system that maintains the temperature in 650 ºC. This furnace heats a steel rod used for testing flammability. A steel cable connected to a linear actuator drives the rod. The main control system is based on an ARM Cortex M0 microcontroller and we developed a PC interface in LabView to acquire data and store it. The equipment built also has a control panel with a push button, status LEDs and temperature indicator. We performed flammability tests in 45 sunglasses: 45 lenses and 45 frames using the equipment described. None of the samples ignited or continued to glow when the test has finished, however, all polycarbonate samples were melted in the contact region with the steel rod. All samples complied with the NBR 15111. The proof argues that the polycarbonate is extremely resistant to ignition.

  1. RESULTS OF COMPRESSION TESTING ON PSEUDO-COHESIVE SOIL

    Directory of Open Access Journals (Sweden)

    Ofrikhter Vadim Grigor’evich

    2015-09-01

    Full Text Available Natural non-treated sand reinforced with randomly oriented short polypropylene fibers of 12 mm in length was tested to determine creep characteristics. This study is a part of the research aimed at encouraging fibrosand (FRS application in subsoils, embankments and retaining wall constructions. Fiber content was accounted for 0.93 %. Twin specimens were put to creep tests (1-D compression using the two curve method. The test results were analyzed and checked with the use of ageing, hardening and hereditary creep theories. On the basis of approximation of the test results the creep deformation equation at constant stress for tested fibrosand was obtained. The assessment of fibrosand secondary compression was carried out by the FORE method. As a result, the value of the void ratio by the end of the secondary compression had been eu=0.7041. For determination of the beginning of the secondary compression the rate equation was superimposed on the empirical curve. The point of the graph divergence is the beginning of the secondary compression process. The secondary compression had begun by the time moment being equal to 9360 min. The void ratio by the beginning of the secondary compression had amounted to 0.70574. Fibrosand is a specific type of improved soil relating to so-called pseudo-cohesive soil. This type of soil is characterized by cohesion like cohesive soils, but, at the same time, by the filtration coefficient of about 1 m per day like non-cohesive soils. Pseudo-cohesive soil testing helps to understand the distinctive features of the stress-strain state of this kind of materials. Municipal solid waste also relates to them.

  2. Long Term Corrosion/Degradation Test Six Year Results

    Energy Technology Data Exchange (ETDEWEB)

    M. K. Adler Flitton; C. W. Bishop; M. E. Delwiche; T. S. Yoder

    2004-09-01

    The Subsurface Disposal Area (SDA) of the Radioactive Waste Management Complex (RWMC) located at the Idaho National Engineering and Environmental Laboratory (INEEL) contains neutron-activated metals from non-fuel, nuclear reactor core components. The Long-Term Corrosion/Degradation (LTCD) Test is designed to obtain site-specific corrosion rates to support efforts to more accurately estimate the transfer of activated elements to the environment. The test is using two proven, industry-standard methods—direct corrosion testing using metal coupons, and monitored corrosion testing using electrical/resistance probes—to determine corrosion rates for various metal alloys generally representing the metals of interest buried at the SDA, including Type 304L stainless steel, Type 316L stainless steel, Inconel 718, Beryllium S200F, Aluminum 6061, Zircaloy-4, low-carbon steel, and Ferralium 255. In the direct testing, metal coupons are retrieved for corrosion evaluation after having been buried in SDA backfill soil and exposed to natural SDA environmental conditions for times ranging from one year to as many as 32 years, depending on research needs and funding availability. In the monitored testing, electrical/resistance probes buried in SDA backfill soil will provide corrosion data for the duration of the test or until the probes fail. This report provides an update describing the current status of the test and documents results to date. Data from the one-year and three-year results are also included, for comparison and evaluation of trends. In the six-year results, most metals being tested showed extremely low measurable rates of general corrosion. For Type 304L stainless steel, Type 316L stainless steel, Inconel 718, and Ferralium 255, corrosion rates fell in the range of “no reportable” to 0.0002 mils per year (MPY). Corrosion rates for Zircaloy-4 ranged from no measurable corrosion to 0.0001 MPY. These rates are two orders of magnitude lower than those specified in

  3. Blind test comparison of the performance and wake flow between two in-line wind turbines exposed to different turbulent inflow conditions

    Directory of Open Access Journals (Sweden)

    J. Bartl

    2017-02-01

    Full Text Available This is a summary of the results of the fourth blind test workshop that was held in Trondheim in October 2015. Herein, computational predictions on the performance of two in-line model wind turbines as well as the mean and turbulent wake flow are compared to experimental data measured at the wind tunnel of the Norwegian University of Science and Technology (NTNU. A detailed description of the model geometry, the wind tunnel boundary conditions and the test case specifications was published before the workshop. Expert groups within computational fluid dynamics (CFD were invited to submit predictions on wind turbine performance and wake flow without knowing the experimental results at the outset. The focus of this blind test comparison is to examine the model turbines' performance and wake development with nine rotor diameters downstream at three different turbulent inflow conditions. Aside from a spatially uniform inflow field of very low-turbulence intensity (TI = 0.23 % and high-turbulence intensity (TI = 10.0 %, the turbines are exposed to a grid-generated highly turbulent shear flow (TI = 10.1 %.Five different research groups contributed their predictions using a variety of simulation models, ranging from fully resolved Reynolds-averaged Navier–Stokes (RANS models to large eddy simulations (LESs. For the three inlet conditions, the power and the thrust force of the upstream turbine is predicted fairly well by most models, while the predictions of the downstream turbine's performance show a significantly higher scatter. Comparing the mean velocity profiles in the wake, most models approximate the mean velocity deficit level sufficiently well. However, larger variations between the models for higher downstream positions are observed. Prediction of the turbulence kinetic energy in the wake is observed to be very challenging. Both the LES model and the IDDES (improved delayed detached eddy simulation model, however

  4. Patch Test Results of 775 Patients with Allergic Contact Dermatitis

    Directory of Open Access Journals (Sweden)

    Simin Ada

    2010-12-01

    Full Text Available Background and Design: The allergens responsible for allergic contact dermatitis vary among countries and even between different geographical regions within the same country over time. It is of great importance to perform the patch test at certain intervals, to evaluate the results in different centers and to compare them afterwards. Our aim was to evaluate the patch test results in our patients with allergic contact dermatitis.Material and Method: The records of the patients with allergic contact dermatitis, who had been patch tested between May 1997 and March 2009, were analyzed retrospectively. The demographic features such as age and sex, localization of the contact dermatitis, and the patch test results were recorded. Results: Of the 775 patients, 581 (75.2% were females and 194 (25% males. Of all patients, 735 were patch tested with the European Standard Series, 318 - with both the European Standard Series and cosmetic series, and 40-with cosmetic series alone. Of the patients tested with the European Standard Series, 255 (34.7% had at least one positive reaction. The most frequent allergen in the European Standard Series was nickel sulfate (17.3%, followed by cobalt chloride (7.2%, potassium dichromate (3%, fragrance mix (2.9%, and p-phenylenediamine base (2.6%. Of the 358 patients tested with cosmetic series, 82 (22.9% had at least one positive reaction. The 5 most frequently observed cosmetic series allergens were octyl gallate (3.9%, thimerosal (2.2%, sorbitan sesquioleate (2%, Euxyl K 400 (2% and methyldibromo glutaronitrile (1.4%. Conclusion: Our study shows the contact allergen profile of our center over 12 years. The most common allergens and their frequency differ between centers in various cities in Turkey. Those geographical differences should be re-evaluated by further studies performed in the certain time period. The high frequency of reactions to octyl gallate is an important finding in patients suspected of cosmetic allergy

  5. PISA TESTS IN LATIN AMERICA: RESULTS IN CONTEXT

    Directory of Open Access Journals (Sweden)

    Guillermina Tiramonti

    2014-05-01

    Full Text Available The educational reforms implemented in Latin America in the ‘90s introduced changes in the modes of regulation of educational systems based on the adoption of mechanisms for assessing student achievement. Since 2000, eight Latin-American countries (Argentina, Chile, Uruguay, Colombia, Brazil, Costa Rica, Mexico and Peru are involved in the PISA tests. The article presents a brief review of the social and educational situation of the Region, relevant for the interpretation and comparative analysis of the results of these tests that is presented below.

  6. Efficacy of bilateral repetitive transcranial magnetic stimulation for negative symptoms of schizophrenia: results of a multicenter double-blind randomized controlled trial.

    Science.gov (United States)

    Dlabac-de Lange, J J; Bais, L; van Es, F D; Visser, B G J; Reinink, E; Bakker, B; van den Heuvel, E R; Aleman, A; Knegtering, H

    2015-04-01

    Few studies have investigated the efficacy of repetitive transcranial magnetic stimulation (rTMS) treatment for negative symptoms of schizophrenia, reporting inconsistent results. We aimed to investigate whether 10 Hz stimulation of the bilateral dorsolateral prefrontal cortex during 3 weeks enhances treatment effects. A multicenter double-blind randomized controlled trial was performed in 32 patients with schizophrenia or schizo-affective disorder, and moderate to severe negative symptoms [Positive and Negative Syndrome Scale (PANSS) negative subscale ⩾15]. Patients were randomized to a 3-week course of active or sham rTMS. Primary outcome was severity of negative symptoms as measured with the Scale for the Assessment of Negative Symptoms (SANS) and the PANSS negative symptom score. Secondary outcome measures included cognition, insight, quality of life and mood. Subjects were followed up at 4 weeks and at 3 months. For analysis of the data a mixed-effects linear model was used. A significant improvement of the SANS in the active group compared with sham up to 3 months follow-up (p = 0.03) was found. The PANSS negative symptom scores did not show a significant change (p = 0.19). Of the cognitive tests, only one showed a significant improvement after rTMS as compared with sham. Finally, a significant change of insight was found with better scores in the treatment group. Bilateral 10 Hz prefrontal rTMS reduced negative symptoms, as measured with the SANS. More studies are needed to investigate optimal parameters for rTMS, the cognitive effects and the neural basis.

  7. 688,112 statistical results : Content mining psychology articles for statistical test results

    NARCIS (Netherlands)

    Hartgerink, C.H.J.

    2016-01-01

    In this data deposit, I describe a dataset that is the result of content mining 167,318 published articles for statistical test results reported according to the standards prescribed by the American Psychological Association (APA). Articles published by the APA, Springer, Sage, and Taylor & Francis

  8. Planar Pixel Sensors for the ATLAS Upgrade: Beam Tests results

    CERN Document Server

    Weingarten, J

    2012-01-01

    The performance of planar silicon pixel sensors, in development for the ATLAS Insertable B-Layer and High Luminosity LHC (HL-LHC) upgrades, has been examined in a series of beam tests at the CERN SPS facilities since 2009. Salient results are reported on the key parameters, including the spatial resolution, the charge collection and the charge sharing between adjacent cells, for different bulk materials and sensor geometries. Measurements are presented for n+-in-n pixel sensors irradiated with a range of fluences and for p-type silicon sensors with various layouts from different vendors. All tested sensors were connected via bump-bonding to the ATLAS Pixel read-out chip. The tests reveal that both n-type and p-type planar sensors are able to collect significant charge even after the lifetime fluence expected at the HL-LHC.

  9. Test beam results from the CMS electromagnetic calorimeter

    CERN Document Server

    Brunelière, R

    2004-01-01

    A precision lead tungstate crystal calorimeter is being constructed by the CMS collaboration. As a key part of the future CMS detector at the LHC, the electromagnetic calorimeter will play a major role in probing electroweak symmetry-breaking and searches for new physics. In order to check that the required performance of the electromagnetic calorimeter is attainable, every prototype is tested in real conditions within a beam of particles. In 2003 two modules of the electromagnetic calorimeter featuring the final mechanical design and electronic architecture have been tested with two different versions of the front-end electronics. In this paper a review of the main results of test beam campaigns in 2002 and 2003 are given. (7 refs).

  10. Results of the quality assurance testing program for radiopharmaceuticals 1995

    International Nuclear Information System (INIS)

    Baldas, J.; Binnyman, J.; Ivanov, Z.; Lauder, R.

    1996-07-01

    The results of the quality assurance testing conducted by the Australian Radiation Laboratory is summarised. Overall 111 batches of 27 different types of radiopharmaceuticals were tested on samples obtained through normal commercial channels. Failure to meet full specifications was observed in 10 of the 111 batches. All technetium-99m cold kits were reconstituted according to the directions in the package insert using sodium pertechnetate ( 99m Tc) injection. Radionuclidic purity has been determined at the calibration time, except for Thallous [ 201 Tl] Chloride injection where the highest impurity level up to product expiry is quoted. Non-compliance of the vial label was observed in one of the ten batches failing specification and was the sole cause of product failure for this batch. Vial label non-compliance consisted of, absence of volume in the vial. Six batches failed the biodistribution test but in no case did this involve failure of the distribution for the target organs. tabs

  11. Results of aircraft positioning tests in postprocessing using the GNSS

    Directory of Open Access Journals (Sweden)

    Henryk JAFERNIK

    2017-06-01

    Full Text Available In this paper, the results of an aircraft’s positioning in aviation during two flight tests are presented. The aircraft’s position was established using GPS data with a sample rate of 1 s in both experiments. The raw GPS data were collected by a Topcon Hiper Pro receiver, which was installed in the pilot’s cabin of a Cessna aircraft. The aircraft’s coordinates in the BLh geodetic frame were determined using the single point positioning (SPP method in gLAB software. The mathematical algorithm for the aircraft’s coordinates are also described in the article. The typical standard deviations for the aircraft’s coordinates were less than 10 m in test I and less than 30 m in test II.

  12. The Marviken critical flow test. A description and early results

    International Nuclear Information System (INIS)

    Hall, D.G.; Ericson, L.

    1978-01-01

    The Marviken critical flow tests are a multinational project designed to obtain critical flow data under conditions similar to those which might occur in a full-scale reactor loss-of-coolant accident. The test facility and procedure used to obtain critical flow data at supply pressures up to 5 MPa and at fluid conditions from 30 0 C subcooling to low-quality saturated conditions are described. Sample data of the type obtained using ruptured-pipe simulators having internal diameters up to 500 mm and length-to-diameter ratios of 1 and 3 are presented and discussed. It is concluded that the results of the tests will probably provide an important measure of the effect of piping size on the critical flow phenomenon and increase the certainty with which critical flows can be predicted in fullscale reactor calculations. (author)

  13. Initial CGE Model Results Summary Exogenous and Endogenous Variables Tests

    Energy Technology Data Exchange (ETDEWEB)

    Edwards, Brian Keith [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Boero, Riccardo [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Rivera, Michael Kelly [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-08-07

    The following discussion presents initial results of tests of the most recent version of the National Infrastructure Simulation and Analysis Center Dynamic Computable General Equilibrium (CGE) model developed by Los Alamos National Laboratory (LANL). The intent of this is to test and assess the model’s behavioral properties. The test evaluated whether the predicted impacts are reasonable from a qualitative perspective. This issue is whether the predicted change, be it an increase or decrease in other model variables, is consistent with prior economic intuition and expectations about the predicted change. One of the purposes of this effort is to determine whether model changes are needed in order to improve its behavior qualitatively and quantitatively.

  14. Reliability test results of LGE pulse tube cryocooler

    Science.gov (United States)

    Kim, S.-Y.; Chung, W.-S.; Park, J.-J.; Hwang, D.-K.; Lee, H.-K.

    2002-05-01

    A low-cost and highly reliable cryocooler is strongly required for several applications. In this circumstance, LG Electronics has developed a 5 W at 65 K pulse tube cryocooler with high potential for low-cost manufacturing based on linear motor and compressor technology. Recently dozens of coolers have been fabricated and tested for the verification of performance stability with ambient temperature variation. From tests at high ambient temperature like 60°C, an average performance degradation of 45% is found and good performance stability of coolers is shown. Continuous operation at 40°C is ongoing for the verification of their reliability. To date no failure has been found. This paper discusses the test process, results and MTBF calculation.

  15. HIV testing and receipt of test results among homeless persons with serious mental illness.

    Science.gov (United States)

    Desai, Mayur M; Rosenheck, Robert A

    2004-12-01

    The purpose of this study was to determine the rates and predictors of HIV testing and receipt of results among homeless adults with serious mental illness in the initial 3-month period after contact with a community-based case management program. Baseline and follow-up interview data came from clients (N=5,890) in the Access to Community Care and Effective Services and Supports program, an 18-site, 5-year federally sponsored demonstration designed to evaluate the effect of service system integration on outcomes for homeless persons with serious mental illness. Overall, 38.0% of clients were tested for HIV in the 3 months after program entry; of these, 88.8% returned to receive their test results. Likelihood of being tested was independently associated with having been tested before, more severe psychiatric symptoms and drug problems, level of worry about getting AIDS, younger age, less education, minority status, longer-term homelessness, being sexually assaulted, being arrested, and health services utilization. Among those tested, likelihood of receiving the test results was higher among those with a history of prior testing and return for results, a higher frequency of testing, and more years of education and lower among those with drug abuse problems, outpatient medical service utilization, disability, and sexually transmitted disease. Interaction analyses showed that, for men, greater social support increased the likelihood of both HIV testing and receipt of results, while sexual victimization during follow-up decreased the likelihood that men would return for their HIV results. The majority of homeless clients enrolled in an intensive case management program were not tested for HIV during the 3-month period after program entry. Among those tested, however, nearly 90% reported receiving their results. The findings may enhance the development and targeting of strategies to increase testing and awareness of HIV serostatus among high-risk mentally ill homeless

  16. Results of gap conductance tests in the power burst facility

    International Nuclear Information System (INIS)

    Garner, R.W.; Sparks, D.T.

    1977-01-01

    Light water reactor (LWR) fuel rod behavior studies are being conducted by the Thermal Fuels Behavior Program of EG and G Idaho, Inc. These studies are being performed under contract to the Energy Research and Development Adminstration at the Idaho National Engineering Laboratory (INEL), as part of the Nuclear Regulatory Commission's Water Reactor Safety Research Fuel Behavior Program. Experimental data for verification of analytical models developed to predict light water nuclear fuel rod behavior under normal and postulated accident conditions are being obtained from a variety of in-reactor and out-of-reactor experiments. This paper summarizes the results of tests performed in the Power Burst Facility (PBF) to obtain data from which the thermal response, gap conductance, and stored energy of LWR fuel rods can be determined. Primary objectives of the PBF gap conductance test program are (a) to obtain data on a variety of pressurized water reactor (PWR) and boiling water reactor (BWR) fuel rod designs, under a wide range of operating conditions, from which gap conductance values can be determined and (b) to evaluate experimentally the power oscillation method for measuring the gap conductance and thermal response of a fresh or burned LWR fuel rod. Tests have been performed with both irradiated and unirradiated PWR-type fuel and with fresh BWR-type fuel rods. Some PWR rod test results are described, and the thermal response data from BWR rod tests are discussed in greater detail. Comparisons are made of gap conductance values determined by the tests with analytically calculated values using the Fuel Rod Analysis Program-Transient (FRAP-T) computer code. These comparisons provide insight into both the experimental measurements methods and the validity of the gap conductance models

  17. Failure to notify reportable test results: significance in medical malpractice.

    Science.gov (United States)

    Gale, Brian D; Bissett-Siegel, Dana P; Davidson, Steven J; Juran, David C

    2011-11-01

    Diagnostic physicians generally acknowledge their responsibility to notify referring clinicians whenever examinations demonstrate urgent or unexpected findings. During the past decade, clinicians have ordered dramatically greater numbers of diagnostic examinations. One study demonstrated that between 1996 and 2003, malpractice payments related to diagnosis increased by approximately 40%. Communication failures are a prominent cause of action in medical malpractice litigation. The aims of this study were to (1) define the magnitude of malpractice costs related to communication failures in test result notification and (2) determine if these costs are increasing significantly. Linear regression analysis of National Practitioner Data Bank claims data from 1991 to 2009 suggested that claims payments increased at the national level by an average of $4.7 million annually (95% confidence interval, $2.98 million to $6.37 million). Controlled Risk Insurance Company/Risk Management Foundation claims data for 2004 to 2008 indicate that communication failures played a role, accounting for 4% of cases by volume and 7% of the total cost. Faile communication of clinical data constitutes an increasing proportion of medical malpractice payments. The increase in cases may reflect expectations of more reliable notification of medical data. Another explanation may be that the remarkable growth in diagnostic test volume has led to a corresponding increase in reportable results. If notification reliability remained unchanged, this increased volume would predict more failed notifications. There is increased risk for malpractice litigation resulting from diagnostic test result notification. The advent of semiautomated critical test result management systems may improve notification reliability, improve workflow and patient safety, and, when necessary, provide legal documentation. Copyright © 2011 American College of Radiology. Published by Elsevier Inc. All rights reserved.

  18. Large-Scale Spray Releases: Additional Aerosol Test Results

    Energy Technology Data Exchange (ETDEWEB)

    Daniel, Richard C.; Gauglitz, Phillip A.; Burns, Carolyn A.; Fountain, Matthew S.; Shimskey, Rick W.; Billing, Justin M.; Bontha, Jagannadha R.; Kurath, Dean E.; Jenks, Jeromy WJ; MacFarlan, Paul J.; Mahoney, Lenna A.

    2013-08-01

    One of the events postulated in the hazard analysis for the Waste Treatment and Immobilization Plant (WTP) and other U.S. Department of Energy (DOE) nuclear facilities is a breach in process piping that produces aerosols with droplet sizes in the respirable range. The current approach for predicting the size and concentration of aerosols produced in a spray leak event involves extrapolating from correlations reported in the literature. These correlations are based on results obtained from small engineered spray nozzles using pure liquids that behave as a Newtonian fluid. The narrow ranges of physical properties on which the correlations are based do not cover the wide range of slurries and viscous materials that will be processed in the WTP and in processing facilities across the DOE complex. To expand the data set upon which the WTP accident and safety analyses were based, an aerosol spray leak testing program was conducted by Pacific Northwest National Laboratory (PNNL). PNNL’s test program addressed two key technical areas to improve the WTP methodology (Larson and Allen 2010). The first technical area was to quantify the role of slurry particles in small breaches where slurry particles may plug the hole and prevent high-pressure sprays. The results from an effort to address this first technical area can be found in Mahoney et al. (2012a). The second technical area was to determine aerosol droplet size distribution and total droplet volume from prototypic breaches and fluids, including sprays from larger breaches and sprays of slurries for which literature data are mostly absent. To address the second technical area, the testing program collected aerosol generation data at two scales, commonly referred to as small-scale and large-scale testing. The small-scale testing and resultant data are described in Mahoney et al. (2012b), and the large-scale testing and resultant data are presented in Schonewill et al. (2012). In tests at both scales, simulants were used

  19. [Cortical blindness].

    Science.gov (United States)

    Chokron, S

    2014-02-01

    Cortical blindness refers to a visual loss induced by a bilateral occipital lesion. The very strong cooperation between psychophysics, cognitive psychology, neurophysiology and neuropsychology these latter twenty years as well as recent progress in cerebral imagery have led to a better understanding of neurovisual deficits, such as cortical blindness. It thus becomes possible now to propose an earlier diagnosis of cortical blindness as well as new perspectives for rehabilitation in children as well as in adults. On the other hand, studying complex neurovisual deficits, such as cortical blindness is a way to infer normal functioning of the visual system. Copyright © 2013 Elsevier Masson SAS. All rights reserved.

  20. Overview of results from 2D airfoil testing at Risoe

    Energy Technology Data Exchange (ETDEWEB)

    Fuglsang, P. [Risoe National Lab., Wind Energy and Atmospheric Physics Dept., Roskilde (Denmark)

    1997-12-31

    This paper gives an overview of the results from two dimensional airfoil testing at Risoe. A two dimensional testing method was recently developed where a test rig is inserted into an open jet flow in a wind tunnel of the close return loop type with an open test section. Pressure measurements provide the lift and drag forces. Both stationary flow and dynamic inflow from pitch motion are possible. The wind tunnel static pressure and total dynamic pressures were calibrated and wind tunnel boundary corrections were found. So far, the testing method was verified by comparison of NACA 63-215 airfoil measurements to numerical predictions and to measurements. Furthermore, the Risoe-1, FFA-W3-241, FFA-W3-301 and NACA 63-430 airfoils were measured. Different types of leading edge roughness and vortex generators were investigated. For all airfoils, good agreements with predictions were obtained on both pressure distribution and on lift coefficient. The drag coefficients were slightly higher than predicted. (eg) 10 refs.

  1. Spent fuel drying system test results (second dry-run)

    International Nuclear Information System (INIS)

    Klinger, G.S.; Oliver, B.M.; Abrefah, J.; Marschman, S.C.; MacFarlan, P.J.; Ritter, G.A.

    1998-07-01

    The water-filled K-Basins in the Hanford 100 Area have been used to store N-Reactor spent nuclear fuel (SNF) since the 1970s. Because some leaks have been detected in the basins and some of the fuel is breached due to handling damage and corrosion, efforts are underway to remove the fuel elements from wet storage. An Integrated Process Strategy (IPS) has been developed to package, dry, transport, and store these metallic uranium fuel elements in an interim storage facility on the Hanford Site (WHC 1995). Information required to support the development of the drying processes, and the required safety analyses, is being obtained from characterization tests conducted on fuel elements removed from the K-Basins. A series of whole element drying tests (reported in separate documents, see Section 7.0) have been conducted by Pacific Northwest National Laboratory (PNNL) on several intact and damaged fuel elements recovered from both the K-East and K-West Basins. This report documents the results of the second dry-run test, which was conducted without a fuel element. With the concurrence of project management, the test protocol for this run, and subsequent drying test runs, was modified. These modifications were made to allow for improved data correlation with drying procedures proposed under the IPS. Details of these modifications are discussed in Section 3.0

  2. Bioequivalence of a biosimilar enoxaparin sodium to Clexane®after single 100 mg subcutaneous dose: results of a randomized, double-blind, crossover study in healthy volunteers.

    Science.gov (United States)

    Martínez González, Javier; Monreal, Mayte; Ayani Almagia, Ignacio; Llaudó Garín, Jordi; Ochoa Díaz de Monasterioguren, Lourdes; Gutierro Adúriz, Ibón

    2018-01-01

    To demonstrate the pharmacokinetic/pharmacodynamic (PK/PD) equivalence of a biosimilar enoxaparin to the reference drug, and to assess its safety and tolerability in healthy volunteers. A randomized, double-blind, crossover, 2-sequence, single-dose study was conducted in healthy volunteers of both sexes. Participants were sequentially and randomly administered single subcutaneous injections of enoxaparin 100 mg manufactured by Rovi (test; Madrid, Spain) and Clexane ® (enoxaparin 100 mg manufactured by Sanofi, reference) separated by a 1-week washout period. The primary PK/PD variables were maximum activity (A max ) and area under the effect curve from time 0 to the last measured activity (T) (AUEC 0-T ) and AUEC from time 0 to infinity (AUEC 0-inf ) of anti-FXa activity, and A max and AUEC 0-T of anti-FIIa activity. Secondary variables were A max and AUEC 0-T , AUEC 0-inf of tissue factor pathway inhibitor, and the ratio of AUEC 0-T anti-FXa to anti-FIIa activity. Biosimilarity would be shown when the 95% CI of the ratio of geometric least squares means (95% CI RGLSMs) of primary PK/PD parameters fell within the standard range of bioequivalence, ie, 80%-125%. The study sample consisted of 46 volunteers (33 males) aged 18-44 years and with body mass index ranging from 19.0 to 31.1 kg/m 2 . Three subjects did not complete the study. The curves of anti-FXa, anti-FIIa and tissue factor pathway inhibitor activities corresponding to administration of the test and reference products were comparable. The 95% CI RGLSMs of A max , AUEC 0-T and AUEC 0-inf for anti-FXa activity were 94.6%-105.9%, 99.8%-108.0% and 100.0%-108.6% respectively; A max and AUEC 0-T for anti-FIIa activity were 94.7%-112.6% and 90.9%-117.9% respectively. In addition, the 95% CI RGLSMs of all secondary variables fell within the range 80%-125%. The incidence and types of adverse events after administration of the test and reference drugs were similar. The results conclusively showed that the enoxaparin

  3. Production Facility Prototype Blower 1000 Hour Test Results

    Energy Technology Data Exchange (ETDEWEB)

    Woloshun, Keith Albert [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Dale, Gregory E. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Romero, Frank Patrick [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Dalmas, Dale Allen [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-10-18

    The roots blower in use at ANL for in-beam experiments and also at LANL for flow tests was sized for 12 mm diameter disks and significantly less beam heating. Currently, the disks are 29 mm in diameter, with a 12 mm FWHM Gaussian beam spot at 42 MeV and 2.86 μA on each side of the target, 5.72 μA total. The target design itself is reported elsewhere. With the increased beam heating, the helium flow requirement increased so that a larger blower was needed for a mass flow rate of 400 g/s at 2.76 MPa (400 psig). An Aerzen GM 12.4 blower was selected, and is now installed at the LANL facility for target and component flow testing. Two extended tests of >1000 hr operation have been completed. Those results and discussion thereof are reported herein. Also included in Appendix A is the detailed description of the blower and its installation, while Appendix B documents the pressure vessel design analysis. The blower has been operated for 1000 hours as a preliminary investigation of long-term performance, operation and possible maintenance issues. The blower performed well, with no significant change in blower head or mass flow rate developed under the operating conditions. Upon inspection, some oil had leaked out of the shaft seal of the blower. The shaft seal and bearing race have been replaced. Test results and conclusions are in Appendix B.

  4. Test Results for the Automated Rendezvous and Capture System

    Science.gov (United States)

    Cruzen, Craig; Dabney, Richard; Lomas, James

    1999-01-01

    The Automated Rendezvous and Capture (AR&C) system was designed and tested at NASA's Marshall Space Flight Center (MSFC) to demonstrate technologies and mission strategies for automated rendezvous and docking of spacecraft in Earth orbit, The system incorporates some of the latest innovations in Global Positioning, System space navigation, laser sensor technologies and automated mission sequencing algorithms. The system's initial design and integration was completed in 1998 and has undergone testing at MSFC. This paper describes the major components of the AR&C system and presents results from the official system tests performed in MSFC's Flight Robotics Laboratory with digital simulations and hardware in the loop tests. The results show that the AR&C system can safely and reliably perform automated rendezvous and docking missions in the absence of system failures with 100 percent success. When system failures are included, the system uses its automated collision avoidance maneuver logic to recover in a safe manner. The primary objective of the AR&C project is to prove that by designing a safe and robust automated system, mission operations cost can be reduced by decreasing the personnel required for mission design, preflight planning and training required for crewed rendezvous and docking missions.

  5. Honeywell Cascade Distiller System Performance Testing Interim Results

    Science.gov (United States)

    Callahan, Michael R.; Sargusingh, Miriam

    2014-01-01

    The ability to recover and purify water through physiochemical processes is crucial for realizing long-term human space missions, including both planetary habitation and space travel. Because of their robust nature, distillation systems have been actively pursued as one of the technologies for water recovery. The Cascade Distillation System (CDS) is a vacuum rotary distillation system with potential for greater reliability and lower energy costs than existing distillation systems. The CDS was previously under development through Honeywell and NASA. In 2009, an assessment was performed to collect data to support down-selection and development of a primary distillation technology for application in a lunar outpost water recovery system. Based on the results of this testing, an expert panel concluded that the CDS showed adequate development maturity, TRL-4, together with the best product water quality and competitive weight and power estimates to warrant further development. The Advanced Exploration Systems (AES) Water Recovery Project (WRP) worked to address weaknesses identified by The Panel; namely bearing design and heat pump power efficiency. Testing at the NASA-JSC Advanced Exploration System Water Laboratory (AES Water Lab) using a prototype Cascade Distillation Subsystem (CDS) wastewater processor (Honeywell International, Torrance, Calif.) with test support equipment and control system developed by Johnson Space Center was performed to evaluate performance of the system with the upgrades. The CDS will also have been challenged with ISS analog waste streams and a subset of those being considered for Exploration architectures. This paper details interim results of the AES WRP CDS performance testing.

  6. Seismic II over I Drop Test Program results and interpretation

    International Nuclear Information System (INIS)

    Thomas, B.

    1993-03-01

    The consequences of non-seismically qualified (Category 2) objects falling and striking essential seismically qualified (Category 1) objects has always been a significant, yet analytically difficult problem, particularly in evaluating the potential damage to equipment that may result from earthquakes. Analytical solutions for impact problems are conservative and available for mostly simple configurations. In a nuclear facility, the open-quotes sourcesclose quotes and open-quotes targetsclose quotes requiring evaluation are frequently irregular in shape and configuration, making calculations and computer modeling difficult. Few industry or regulatory rules are available on this topic even though it is a source of considerable construction upgrade costs. A drop test program was recently conducted to develop a more accurate understanding of the consequences of seismic interactions. The resulting data can be used as a means to improve the judgment of seismic qualification engineers performing interaction evaluations and to develop realistic design criteria for seismic interactions. Impact tests on various combinations of sources and targets commonly found in one Savannah River Site (SRS) nuclear facility were performed by dropping the sources from various heights onto the targets. This report summarizes results of the Drop Test Program. Force and acceleration time history data are presented as well as general observations on the overall ruggedness of various targets when subjected to impacts from different types of sources

  7. Comparison of road load simulator test results with track tests on electric vehicle propulsion system

    Science.gov (United States)

    Dustin, M. O.

    1983-01-01

    A special-purpose dynamometer, the road load simulator (RLS), is being used at NASA's Lewis Research Center to test and evaluate electric vehicle propulsion systems developed under DOE's Electric and Hybrid Vehicle Program. To improve correlation between system tests on the RLS and track tests, similar tests were conducted on the same propulsion system on the RLS and on a test track. These tests are compared in this report. Battery current to maintain a constant vehicle speed with a fixed throttle was used for the comparison. Scatter in the data was greater in the track test results. This is attributable to variations in tire rolling resistance and wind effects in the track data. It also appeared that the RLS road load, determined by coastdown tests on the track, was lower than that of the vehicle on the track. These differences may be due to differences in tire temperature.

  8. Small-Scale Spray Releases: Additional Aerosol Test Results

    Energy Technology Data Exchange (ETDEWEB)

    Schonewill, Philip P.; Gauglitz, Phillip A.; Kimura, Marcia L.; Brown, G. N.; Mahoney, Lenna A.; Tran, Diana N.; Burns, Carolyn A.; Kurath, Dean E.

    2013-08-01

    One of the events postulated in the hazard analysis at the Waste Treatment and Immobilization Plant (WTP) and other U.S. Department of Energy (DOE) nuclear facilities is a breach in process piping that produces aerosols with droplet sizes in the respirable range. The current approach for predicting the size and concentration of aerosols produced in a spray leak involves extrapolating from correlations reported in the literature. These correlations are based on results obtained from small engineered spray nozzles using pure liquids with Newtonian fluid behavior. The narrow ranges of physical properties on which the correlations are based do not cover the wide range of slurries and viscous materials that will be processed in the WTP and across processing facilities in the DOE complex. To expand the data set upon which the WTP accident and safety analyses were based, an aerosol spray leak testing program was conducted by Pacific Northwest National Laboratory (PNNL). PNNL’s test program addressed two key technical areas to improve the WTP methodology (Larson and Allen 2010). The first technical area was to quantify the role of slurry particles in small breaches where slurry particles may plug the hole and prevent high-pressure sprays. The results from an effort to address this first technical area can be found in Mahoney et al. (2012a). The second technical area was to determine aerosol droplet size distribution and total droplet volume from prototypic breaches and fluids, including sprays from larger breaches and sprays of slurries for which literature data are largely absent. To address the second technical area, the testing program collected aerosol generation data at two scales, commonly referred to as small-scale and large-scale. The small-scale testing and resultant data are described in Mahoney et al. (2012b) and the large-scale testing and resultant data are presented in Schonewill et al. (2012). In tests at both scales, simulants were used to mimic the

  9. The first operation of the Delphos plant: Test results

    International Nuclear Information System (INIS)

    Sarno, A.; Noviello, G.; Cordisco, S.; Di Paola, L.; Guerra, M.

    1991-09-01

    The data collected during the O and M of the Delphos plant and the testing results are presented and discussed. Together with the maintenance influence on the operation and production of the plant, the various downtime causes are pointed out. An extensive activity has been carried out to investigate the actual behaviour of the photovoltaic generator and the power conditioning unit. The analysis of the experimental results allows to focus on the different causes of loss and suggest some actions to be taken in order to improve the plant efficiency and increase the energy production. (author)

  10. SCD1 thermal design and test result analysis

    Science.gov (United States)

    Cardoso, Humberto Pontes; Muraoka, Issamu; Mantelli, Marcia Barbosa Henriques; Leite, Rosangela M. G.

    1990-01-01

    The SCD 01 (Satelite de Coleta de Dados 01) is a spin stabilized low Earth orbit satellite dedicated to the collection and distribution of environmental data. It was completely developed at the Brazilian Institute for Space Research (INPE) and is scheduled to be launched in 1992. The SCD 01 passive thermal control design configuration is presented and the thermal analysis results are compared with the temperatures obtained from a Thermal Balance Test. The correlation between the analytical and experimental results is considered very good. Numerical flight simulations show that the thermal control design can keep all the subsystem temperatures within their specified temperature range.

  11. An integral topical gel for cellulite reduction: results from a double-blind, randomized, placebo-controlled evaluation of efficacy.

    Science.gov (United States)

    Dupont, Eric; Journet, Michel; Oula, Marie-Laure; Gomez, Juan; Léveillé, Claude; Loing, Estelle; Bilodeau, Diane

    2014-01-01

    Cellulite is a serious cosmetic concern for most of the 90% of women affected by it. To assess the clinical efficacy of a complex integral anti-cellulite gel. This double-blind, randomized, placebo-controlled study involved 44 healthy women, aged 25-55 years. Subjects had a normal to slightly overweight body mass index and presented slight to moderate cellulite on their thighs, buttocks, and/or hips at baseline. Subjects were randomly assigned to either the treated or placebo group and accordingly applied the active product or placebo on their hips, stomach, buttocks, and thighs, twice daily for 3 months. Skin tonicity, orange-peel aspect, and stubborn cellulite were assessed at day 0, 28, 56, and 84. A self-evaluation questionnaire was completed by all volunteers. At the end of the study, an average of 81% of the subjects applying the active product presented improvement in their cellulite condition versus 32% for the placebo group (all descriptors and sites combined). At day 84, skin tonicity, orange-peel appearance, and stubborn cellulite were improved in a significant manner (Pcellulite was reduced on average by -19% for buttocks, -24% for hips, and -22% for thighs. Circumference measurements decreased in a significant manner (Pcellulite and reshape the silhouette.

  12. Comparative test results for two ODE solvers: EPISODE and GEAR

    Energy Technology Data Exchange (ETDEWEB)

    Byrne, G.D.; Hindmarsh, A.C.; Jackson, K.R.; Brown, H.G.

    1977-03-01

    This is a sequel to the paper ''A comparison of two ODE codes: GEAR and EPISODE,'' and is concerned with the testing of two superficially similar ODE packages, GEAR and EPISODE. Fourteen basic test problems, some with several cases, are the basis for the testing. These problems represent several types--nonlinear systems with real and complex eigenvalues, linear systems with varied diagonal dominance, linear scalar problems, stiff and nonstiff problems, chemical kinetics with and without diurnal effect, and systems arising from the use of the numerical method of lines. Some problems are included in order to examine the options and error returns. The test results are presented in two forms: raw output and a comparative display of operation counts and of timings for the best method in the GEAR package and the best method in the EPISODE package. This approach allows a comparison of the consequences of the fixed-step interpolate strategy (GEAR) for changing step size against the truly variable step size strategy (EPISODE). It is concluded that EPISODE is generally faster than GEAR for problems involving wave fronts or transients on the interior of the interval of integration. For linear or simply decaying problems, these roles are usually reversed. 19 figures, 116 tables.

  13. Automation and results of Adjacent Band Emission testing

    Science.gov (United States)

    2015-03-01

    Problem Statement : Multiple groups conduct tests in various ways - Outcomes vary based on test setup and assumptions - No standard has been established to conduct such tests - Spectrum is scarce and the need for compliance testing will only increase...

  14. Postural control in blind subjects

    Directory of Open Access Journals (Sweden)

    Antonio Vinicius Soares

    2011-12-01

    Full Text Available Objective: To analyze postural control in acquired and congenitally blind adults. Methods: A total of 40 visually impaired adults participated in the research, divided into 2 groups, 20 with acquired blindness and 20 with congenital blindness - 21 males and 19 females, mean age 35.8 ± 10.8. The Brazilian version of Berg Balance Scale and the motor domain of functional independence measure were utilized. Results: On Berg Balance Scale the mean for acquired blindness was 54.0 ± 2.4 and 54.4 ± 2.5 for congenitally blind subjects; on functional independence measure the mean for acquired blind group was 87.1 ± 4.8 and 87.3 ± 2.3 for congenitally blind group. Conclusion: Based upon the scale used the results suggest the ability to control posture can be developed by compensatory mechanisms and it is not affected by visual loss in congenitally and acquired blindness.

  15. Functional Fitness Testing Results Following Long-Duration ISS Missions.

    Science.gov (United States)

    Laughlin, Mitzi S; Guilliams, Mark E; Nieschwitz, Bruce A; Hoellen, David

    2015-12-01

    Long-duration spaceflight missions lead to the loss of muscle strength and endurance. Significant reduction in muscle function can be hazardous when returning from spaceflight. To document these losses, NASA developed medical requirements that include measures of functional strength and endurance. Results from this Functional Fitness Test (FFT) battery are also used to evaluate the effectiveness of in-flight exercise countermeasures. The purpose of this paper is to document results from the FFT and correlate this information with performance of in-flight exercise on board the International Space Station. The FFT evaluates muscular strength and endurance, flexibility, and agility and includes the following eight measures: sit and reach, cone agility, push-ups, pull-ups, sliding crunches, bench press, leg press, and hand grip dynamometry. Pre- to postflight functional fitness measurements were analyzed using dependent t-tests and correlation analyses were used to evaluate the relationship between functional fitness measurements and in-flight exercise workouts. Significant differences were noted post space flight with the sit and reach, cone agility, leg press, and hand grip measurements while other test scores were not significantly altered. The relationships between functional fitness and in-flight exercise measurements showed minimal to moderate correlations for most in-flight exercise training variables. The change in FFT results can be partially explained by in-flight exercise performance. Although there are losses documented in the FFT results, it is important to realize that the crewmembers are successfully performing activities of daily living and are considered functional for normal activities upon return to Earth.

  16. Results of field testing of waste forms using lysimeters

    International Nuclear Information System (INIS)

    McConnell, J.W. Jr.; Rogers, R.D.

    1990-01-01

    The TMI-2 [Three Mile Island Unit 2] EPICOR-II Resin/Liner Low-Level Waste Data Base Development Program, funded by the U.S. Nuclear Regulatory Commission (NRC), is obtaining information on the performance of radioactive waste in a disposal environment. Waste forms fabricated using ion-exchange resins from EPICOR-II prefilters employed in the cleanup of the Three Mile Island Nuclear Power Station are being tested to: (a) develop a low-level waste data base, and (b) obtain information on survivability of waste forms in a disposal environment. This paper updates field testing of those waste forms during FY-1989. The results of the lysimeters is presented and the use of lysimeter data in performance assessment is discussed. 16 refs., 10 figs., 5 tabs

  17. LEDA RF distribution system design and component test results

    International Nuclear Information System (INIS)

    Roybal, W.T.; Rees, D.E.; Borchert, H.L.; McCarthy, M.; Toole, L.

    1998-01-01

    The 350 MHz and 700 MHz RF distribution systems for the Low Energy Demonstration Accelerator (LEDA) have been designed and are currently being installed at Los Alamos National Laboratory. Since 350 MHz is a familiar frequency used at other accelerator facilities, most of the major high-power components were available. The 700 MHz, 1.0 MW, CW RF delivery system designed for LEDA is a new development. Therefore, high-power circulators, waterloads, phase shifters, switches, and harmonic filters had to be designed and built for this applications. The final Accelerator Production of Tritium (APT) RF distribution systems design will be based on much of the same technology as the LEDA systems and will have many of the RF components tested for LEDA incorporated into the design. Low power and high-power tests performed on various components of these LEDA systems and their results are presented here

  18. Using Large Scale Test Results for Pedagogical Purposes

    DEFF Research Database (Denmark)

    Dolin, Jens

    2012-01-01

    , and the teachers’ and students’ use of this information for pedagogical purposes in the classroom. We know well how the policy makers interpret and use the outcomes of such tests, but we know less about how teachers make use of LSTs to inform their pedagogical practice. An important question is whether...... there is a contradiction between the political system’s use of LST and teachers’ (possible) pedagogical use of LST. And if yes: What is a contradiction based on? This presentation will give some results from a systematic review on how tests have influenced the pedagogical practice. The research revealed many of the fatal...... system and the different theoretical foundations of PISA and most teachers’ pedagogically oriented, formative assessment, thus explaining the teacher resentment towards LSTs. Finally, some principles for linking LSTs to teachers’ pedagogical practice will be presented....

  19. One-year results of a prospective randomized, evaluator-blinded, multicenter study comparing TVT and TVT Secur.

    Science.gov (United States)

    Andrada Hamer, Maria; Larsson, Per-Göran; Teleman, Pia; Bergqvist, Christina Eten; Persson, Jan

    2013-02-01

    The aim of this prospective randomized multicenter study was to compare retropubic tension-free vaginal tape (TVT) with TVT Secur in terms of efficacy and safety. We set out to enrol 280 stress urinary incontinent (SUI) women with a half-time interim analysis of short-term cure and adverse events. The short-term results have previously been published. Of the 133 randomized women, 125 underwent surgery, and 121 (TVT n = 61, TVT Secur n = 60) were available for follow-up 1 year postsurgery. No significant differences were found between groups regarding demographics or incontinence grade. One year after surgery, both subjective and objective cure rates were significantly lower for TVT Secur than for TVT (subjective cure: TVT 98 %, TVT Secur 80 %, p = 0.03; objective cure: TVT 94 %, TVT Secur 71 % for cough test, p = 0.01; TVT 76 %, TVT Secur 58 % for pad test, p = 0.05 ). Three major complications occurred in the TVT Secur group: one tape erosion into the urethra, one tape inadvertently placed into the bladder, and one immediate postoperative bleeding due to injury to the corona mortis. No major complications occurred in the TVT group. No significant differences were found between groups regarding peroperative bleeding, hospital stay, urge symptoms, residual urinary volume, subjective bladder emptying problems, postoperative urinary tract infections, and minor complications. The TVT Secur group used more antimuscarine medication after surgery than the TVT group (p = 0.03). Median time for surgery was 13 and 22 min for TVT Secur and TVT, respectively (p TVT Secur procedure had significantly inferior subjective and objective cure rates compared with the retropubic TVT procedure. Three serious adverse events occurred in the TVT Secur group. We therefore discourage further use of TVT Secur.

  20. Poor Safety and Tolerability Hamper Reaching a Potentially Therapeutic Dose in the Use of Thalidomide for Alzheimer's Disease: Results from a Double-Blind, Placebo-Controlled Trial.

    Science.gov (United States)

    Decourt, Boris; Drumm-Gurnee, Denise; Wilson, Jeffrey; Jacobson, Sandra; Belden, Christine; Sirrel, Sherye; Ahmadi, Michael; Shill, Holly; Powell, Jessica; Walker, Aaron; Gonzales, Amanda; Macias, Mimi; Sabbagh, Marwan N

    2017-01-01

    To date there is no cure for Alzheimer's disease (AD). After amyloid beta immunotherapies have failed to meet primary endpoints of slowing cognitive decline in AD subjects, the inhibition of the beta-secretase BACE1 appears as a promising therapeutic approach. Pre-clinical data obtained in APP23 mice suggested that the anti-cancer drug thalidomide decreases brainBACE1 and Aβ levels. This prompted us to develop an NIH-supported Phase IIa clinical trial to test the potential of thalidomide for AD. We hypothesized that thalidomide can decrease or stabilize brain amyloid deposits, which would result in slower cognitive decline in drug- versus placebo-treated subjects. This was a 24-week, randomized, double-blind, placebo-controlled, parallel group study with escalating dose regimen of thalidomide with a target dose of 400mg daily in patients with mild to moderate AD. The primary outcome measures were tolerability and cognitive performance assessed by a battery of tests. A total of 185 subjects have been pre-screened, out of which25 were randomized. Mean age of the sample at baseline was 73.64 (±7.20) years; mean education was 14.24 (±2.3) years; mean MMSE score was 21.00 (±5.32); and mean GDS score was 2.76 (±2.28).Among the 25 participants, 14 (56%) terminated early due to adverse events, dramatically decreasing the power of the study. In addition, those who completed the study (44%) never reached the estimated therapeutic dose of 400 mg/day thalidomide because of reported adverse events. The cognitive data showed no difference between the treated and placebo groups at the end of the trial. This study demonstrates AD patients have poor tolerability for thalidomide, and are unable to reach a therapeutic dose felt to be sufficient to have effects on BACE1. Because of poor tolerability, this study failed to demonstrate a beneficial effect on cognition. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

  1. The Castor 120 (TM) motor: Development and qualification testing results

    Science.gov (United States)

    Hilden, Jack G.; Poirer, Beverly M.

    1993-01-01

    This paper discusses Thiokol Corporation's static test results for the development and qualification program of the Castor 120(TM) motor. The demonstration program began with a 25,000-pound motor to demonstrate the new technologies and processes that would be used on the larger Castor 120(TM) motor. The Castor 120(TM) motor was designed to be applicable as a first stage, second stage, or strap-on motor. Static test results from the Castor 25 and two Castor 120(TM) motors are discussed in this paper. The results verified the feasibility of tailoring the propellant grain configuration and nozzle throat diameter to meet various customer requirements. The first and second motors were conditioned successfully at ambient temperature and 28 F, respectively, to demonstrate that the design could handle a wide range of environmental launch conditions. Furthermore, the second Castor 120(TM) motor demonstrated a systems tunnel and forward skirt extension to verify flight-ready stage hardware. It is anticipated that the first flight motor will be ready by the fall of 1994.

  2. Expose : procedure and results of the joint experiment verification tests

    Science.gov (United States)

    Panitz, C.; Rettberg, P.; Horneck, G.; Rabbow, E.; Baglioni, P.

    The International Space Station will carry the EXPOSE facility accommodated at the universal workplace URM-D located outside the Russian Service Module. The launch will be affected in 2005 and it is planned to stay in space for 1.5 years. The tray like structure will accomodate 2 chemical and 6 biological PI-experiments or experiment systems of the ROSE (Response of Organisms to Space Environment) consortium. EXPOSE will support long-term in situ studies of microbes in artificial meteorites, as well as of microbial communities from special ecological niches, such as endolithic and evaporitic ecosystems. The either vented or sealed experiment pockets will be covered by an optical filter system to control intensity and spectral range of solar UV irradiation. Control of sun exposure will be achieved by the use of individual shutters. To test the compatibility of the different biological systems and their adaptation to the opportunities and constraints of space conditions a profound ground support program has been developed. The procedure and first results of this joint Experiment Verification Tests (EVT) will be presented. The results will be essential for the success of the EXPOSE mission and have been done in parallel with the development and construction of the final hardware design of the facility. The results of the mission will contribute to the understanding of the organic chemistry processes in space, the biological adaptation strategies to extreme conditions, e.g. on early Earth and Mars, and the distribution of life beyond its planet of origin.

  3. Topical Minocycline Foam for the Treatment of Impetigo in Children: Results of a Randomized, Double-Blind, Phase 2 Study.

    Science.gov (United States)

    Chamny, Shlomo; Miron, Dan; Lumelsky, Nadia; Shalev, Hana; Gazal, Elana; Keynan, Rita; Shemer, Avner; Tamarkin, Dov

    2016-10-01

    Currently available treatment options for impetigo are limited by either systemic side effects (for oral therapy) or lack of ease of use (for topical ointment). A novel foam formulation of minocycline for topical use may improve convenience and treatment utilization for pediatric patients with impetigo. To evaluate the safety and efficacy of topically applied minocycline foam (FMX-102 1% and 4%) in the treatment of impetigo and to determine the optimal therapeutic active ingredient concentration. In this randomized, parallel-group, double-blind, comparative clinical trial, 32 subjects aged ≥2 years with a clinical diagnosis of pure impetigo, impetigo contagiosa, or uncomplicated blistering impetigo were randomized to treatment with FMX-102 1% or 4%, twice daily for 7 days. Subjects were followed for up to 7 days post-treatment. Clinical cure, defined as ≥80% cured lesions (fully recovered lesions, visually determined by investigators), was achieved by 57.1% and 50.0% of FMX-102 1% and 4% subjects, respectively, at the end of treatment (visit 3). Clinical success, defined as the absence of lesions, or the drying or improvement of treated lesions (decrease in size of affected area, lesion number, or both), was demonstrated in 81.3% and 78.6% of FMX-102 1% and 4% subjects, respectively, following 3 days of treatment (visit 2), in 92.3% and 100% of the respective subjects at the end of treatment, and in 100% in both groups at follow-up (visit 4). Bacteriologic success rates at the end of treatment, defined as complete pathogen eradication, were 85% and 74% in the FMX-102 1% and 4% groups, respectively. The bacteriologic success rate for MRSA infections was 100% (11/11), with no recurrences. Both FMX-102 1% and 4% were considered well tolerated and safe. Topical minocycline foam may be a safe and effective new treatment option for impetigo in children, including those with MRSA. J Drugs Dermatol. 2016;15(10):1238-1243.

  4. The effect of solifenacin on postvoid dribbling in women: results of a randomized, double-blind placebo-controlled trial.

    Science.gov (United States)

    Ablove, Tova; Bell, Lauren N; Liang, Hong; Chappell, Richard J; Toklu, Hale Z; Yale, Steven H

    2018-03-24

    To determine the effectiveness of the muscarinic receptor antagonist solifenacin (VESIcare®) in the treatment of postvoid dribbling (PVD). We carried out a multicenter, 12-week, double-blind, randomized, placebo-controlled, parallel design study. Between 2012 and 2015, a total of 118 women (age 18-89 years) with PVD at least twice/weekly, were randomized to receive solifenacin (5 mg; n = 58) or placebo (n = 60) once daily. The primary outcome was the percentage reduction in PVD episodes. Secondary outcomes included the percentage of patients with ≥50% reduction in PVD episodes and changes in quality of life. There were no differences in either the primary or secondary outcome variables. Subgroup analysis, based on those with more severe disease (>10 PVD episodes/week), showed a greater and significant percentage reduction in the frequency of PVD episodes per day (60.3% vs 32.1%; p = 0.035) and a higher percentage of patients showing ≥50% reduction in the frequency of PVD episodes with solifenacin (68.1% vs 45.8%; p = 0.0476). A significant solifenacin effect occurred at week 2 and continued through week 12 for the subgroup. For solifenacin, PVD reduction was the same for the entire cohort and subgroup, whereas for placebo, it was 10% lower in the subgroup, declining from 42% to 32%. There were no differences in PVD outcomes between the solifenacin and placebo groups. Solifenacin may play a role in treating women with the most severe symptoms. Because of the powerful placebo response seen in this study, behavior-based interventions may be useful for treating PVD.

  5. THE LT-CFB GASIFIER – FIRST TEST RESULTS FROM THE 500 KW TEST PLANT

    DEFF Research Database (Denmark)

    Nielsen, Rasmus Glar; Stoholm, Peder; Nielsen, Mads Brix

    2005-01-01

    The Low Temperature Circulating Fluidised Bed (LT-CFB) gasification process is briefly described together with the first test results from the new 500 kW test plant. The process aims primarily at co-firing low grade biomass and waste products at power plants and offer several advantages to direct...

  6. New STS-1 Electronics: Development and Test Results

    Science.gov (United States)

    Uhrhammer, R. A.; Karavas, B.; Friday, J.; Vanzandt, T.; Hutt, C. R.; Wielandt, E.; Romanowicz, B.

    2007-12-01

    refinements, this generation of electronics was operated on two seismometers concurrently and successfully run through swept sine and step calibration functions on four seismometers. During this final phase, the Metrozet electronics included the ability to initiate and operate the calibrations via a network (Ethernet) connection. Most of the calibration testing was performed remotely from Metrozet's Southern California office over the BSL network. Metrozet was able to remotely log into the Berkeley network, establish a connection to the test bed in the Byerly seismic vault and initiate control of the seismometer including remote centering and calibration functions. Finally, after BSL tests were completed and the development appeared complete and satisfactory, the new electronics were tested at the Albuquerque Seismological Laboratory's seismic vault, which is located in a quieter environment than BKS. The new electronics package was also field tested at the BDSN broadband station HOPS. We present detailed results of the calibrations.

  7. Advanced stellar compass deep space navigation, ground testing results

    DEFF Research Database (Denmark)

    Betto, Maurizio; Jørgensen, John Leif; Jørgensen, Peter Siegbjørn

    2006-01-01

    . Nevertheless, up to now, ground navigation has been the only possible solution. The technological breakthrough of advanced star trackers, like the micro-advanced stellar compass (mu ASC) might change this situation. Indeed, exploiting the capabilities of this instrument, the authors have devised a method...... to determine the orbit of a spacecraft autonomously, on-board and without any a priori knowledge of any kind. The solution is robust, elegant and fast. This paper presents the preliminary performances obtained during the ground tests. The results are very positive and encouraging....

  8. Assessing Equivalent Viscous Damping Using Piping System test Results

    Energy Technology Data Exchange (ETDEWEB)

    Nie, J.; Morante, R.

    2010-07-18

    The specification of damping for nuclear piping systems subject to seismic-induced motions has been the subject of many studies and much controversy. Damping estimation based on test data can be influenced by numerous factors, consequently leading to considerable scatter in damping estimates in the literature. At present, nuclear industry recommendations and nuclear regulatory guidance are not consistent on the treatment of damping for analysis of nuclear piping systems. Therefore, there is still a need to develop a more complete and consistent technical basis for specification of appropriate damping values for use in design and analysis. This paper summarizes the results of recent damping studies conducted at Brookhaven National Laboratory.

  9. The space telescope NINA: results of a beam test calibration

    CERN Document Server

    Bidoli, V; Pascale, M P D; Morselli, A; Furano, G; Picozza, P; Scoscini, A; Sparvoli, R; Barbiellini, G; Bonvicini, W; Cirami, R; Schiavon, Paolo; Vacchi, A; Zampa, N; Ambriola, M; Bellotti, R; Cafagna, F; Ciacio, F; Castellano, M; Circella, M; Marzo, C D; Bartalucci, S; Giuntoli, S; Ricci, M; Papini, P; Piccardi, S; Spillantini, P; Bakaldin, A; Batishev, A; Galper, A M; Koldashov, S; Korotkov, M; Mikhailov, V; Murashov, A; Voronov, S; Boezio, M

    1999-01-01

    In June 1998 the telescope NINA will be launched in space on board of the Russian satellite Resource-01 n.4. The main scientific objective of the mission is the study of the anomalous, galactic and solar components of the cosmic rays in the energy interval 10-200 MeV/n. The core of the instrument is a silicon detector whose performances have been tested with a particle beam at the GSI Laboratory in Germany in 1997; we report here on the results obtained during the beam calibration.

  10. Hanford coring bit temperature monitor development testing results report

    International Nuclear Information System (INIS)

    Rey, D.

    1995-05-01

    Instrumentation which directly monitors the temperature of a coring bit used to retrieve core samples of high level nuclear waste stored in tanks at Hanford was developed at Sandia National Laboratories. Monitoring the temperature of the coring bit is desired to enhance the safety of the coring operations. A unique application of mature technologies was used to accomplish the measurement. This report documents the results of development testing performed at Sandia to assure the instrumentation will withstand the severe environments present in the waste tanks

  11. Plutonium immobilization program - Cold pour Phase 1 test results

    International Nuclear Information System (INIS)

    Hamilton, L.

    2000-01-01

    The Plutonium Immobilization Project will disposition excess weapons grade plutonium. It uses the can-in-canister approach that involves placing plutonium-ceramic pucks in sealed cans that are then placed into Defense Waste Processing Facility canisters. These canisters are subsequently filled with high-level radioactive waste glass. This process puts the plutonium in a stable form and makes it unattractive for reuse. A cold (non-radioactive) glass pour program was performed to develop and verify the baseline design for the canister and internal hardware. This paper describes the Phase 1 scoping test results

  12. Plutonium Immobilization Program - Cold pour Phase 1 test results

    International Nuclear Information System (INIS)

    Hamilton, L.

    2000-01-01

    The Plutonium Immobilization Project will disposition excess weapons grade plutonium. It uses the can-in-canister approach that involves placing plutonium-ceramic pucks in sealed cans that are then placed into Defense Waste Processing Facility canisters. These canisters are subsequently filled with high-level radioactive waste glass. This process puts the plutonium in a stable form and makes it unattractive for reuse. A cold (non-radioactive) glass pour program was performed to develop and verify the baseline design for the canister and internal hardware. This paper describes the Phase 1 scoping test results

  13. Bridge Testing With Ground-Based Interferometric Radar: Experimental Results

    Science.gov (United States)

    Chiara, P.; Morelli, A.

    2010-05-01

    The research of innovative non-contact techniques aimed at the vibration measurement of civil engineering structures (also for damage detection and structural health monitoring) is continuously directed to the optimization of measures and methods. Ground-Based Radar Interferometry (GBRI) represents the more recent technique available for static and dynamic control of structures and ground movements. Dynamic testing of bridges and buildings in operational conditions are currently performed: (a) to assess the conformity of the structure to the project design at the end of construction; (b) to identify the modal parameters (i.e. natural frequencies, mode shapes and damping ratios) and to check the variation of any modal parameters over the years; (c) to evaluate the amplitude of the structural response to special load conditions (i.e. strong winds, earthquakes, heavy railway or roadway loads). If such tests are carried out by using a non-contact technique (like GBRI), the classical issues of contact sensors (like accelerometers) are easily overtaken. This paper presents and discusses the results of various tests carried out on full-scale bridges by using a Stepped Frequency-Continuous Wave radar system.

  14. Test Results for LHC Insertion Region Dipole Magnets

    CERN Document Server

    Muratore, Joseph F; Cozzolino, John P; Ganetis, George; Ghosh, Arup; Gupta, Ramesh C; Harrison, Michael; Kumar-Jain, Animesh; Marone, Andrew; Richard-Plate, Stephen; Schmalzle, Jesse D; Thomas, Richard A; Wanderer, Peter; Willen, Erich; Wu, Kuo-Chen

    2005-01-01

    The Superconducting Magnet Division at Brookhaven National Laboratory (BNL) has made 20 insertion region dipoles for the Large Hadron Collider (LHC) at CERN. These 9.45 m-long, 8 cm aperture magnets have the same coil design as the arc dipoles now operating in the Relativistic Heavy Ion Collider (RHIC) at BNL and are of single aperture, twin aperture, and double cold mass configurations. They produce fields up to 3.8 T for operation at 7.56 TeV. Eighteen of these magnets have been tested at 4.5 K using either forced flow supercritical helium or liquid helium. The testing was especially important for the twin aperture models, which have the most challenging design. In these, the dipole fields in both apertures point in the same direction, unlike LHC arc dipoles. This paper reports on the results of these tests, including spontaneous quench performance, verification of quench protection heater operation, and magnetic field quality. Magnetic field measurements were done at 4.5K and at room temperature, and warm-...

  15. Pathfinder Technology Demonstrator: GlobalStar Testing and Results

    Science.gov (United States)

    Kuroda, Vanessa; Limes, Gregory L.; Han, Shi Lei; Hanson, John Eric; Christa, Scott E.

    2016-01-01

    The communications subsystem of a spacecraft is typically a SWaP (size, weight, and power) intensive subsystem in a SWaP constrained environment such as a CubeSat. Use of a satellite-based communication system, such as GlobalStars duplex GSP-1720 radio is a low SWaP potentially game-changing low-cost communication subsystem solution that was evaluated for feasibility for the NASA Pathfinder Technology Demonstrator (PTD) project. The PTD project is a series of 6U CubeSat missions to flight demonstrate and characterize novel small satellite payloads in low Earth orbit. GlobalStar is a low Earth orbit satellite constellation for satellite phone and low-speed data communications, and the GSP-1720 is their single board duplex radio most commonly used in satellite phones and shipment tracking devices. The PTD project tested the GSP-1720 to characterize its viability for flight using NASA GEVS (General Environmental Verification Standard) vibration and thermal vacuum levels, as well as testing the uplink-downlink connectivity, data throughput, and file transfer capabilities. This presentation will present the results of the environmental and capability testing of the GSP-1720 performed at NASA Ames Research Center, as well as the viability for CubeSat use in LEO.

  16. Results of Ageing Tests on the Forward MSGC 'BANANA' Prototype

    CERN Document Server

    Boimska, B; Capéans-Garrido, M; Claes, S; Hoch, Michael; Million, Gilbert; Ropelewski, Leszek; Sharma, Abhishek; Shekhtman, L I; Van Doninck, Walter; Van Lancker, Luc

    1996-01-01

    The forward tracker of the CMS experiment at CERN will consist of a large number of MicroStrip Gas Chambers ( MSGCs), expected to operate for several years in the high luminosity environment of LHC with an accumulated dose rate of ~ 10 mC/yr per cm of strip. They are planned to be arranged around the interaction point in modular wheels which contain several MSGCs. The 'open'option of a forward CMS 'banana' module includes the electronics inside the gas volume. Long term tests of one such prototype containing two plates, one with gold and the other with chromium strips on diamond-like coated D263 glass with representative electronics and surface mount components inside the gas volume have been performed; the satisfactory results are reported here. A first test has been made with a gas flow rate of 60 cc/min in the prototype ( corresponding to 5 gas renewals per hour) and has shown no gain drop up to 85 mC/cm of accumulated charge per strip. A second test has been performed with a gas flow rate of 6 cc/min corr...

  17. Results from Field Testing the RIMFAX GPR on Svalbard.

    Science.gov (United States)

    Hamran, S. E.; Amundsen, H. E. F.; Berger, T.; Carter, L. M.; Dypvik, H.; Ghent, R. R.; Kohler, J.; Mellon, M. T.; Nunes, D. C.; Paige, D. A.; Plettemeier, D.; Russell, P.

    2017-12-01

    The Radar Imager for Mars' Subsurface Experiment - RIMFAX is a Ground Penetrating Radar being developed for NASÁs MARS 2020 rover mission. The principal goals of the RIMFAX investigation are to image subsurface structures, provide context for sample sites, derive information regarding subsurface composition, and search for ice or brines. In meeting these goals, RIMFAX will provide a view of the stratigraphic section and a window into the geological and environmental history of Mars. To verify the design an Engineering Model (EM) of the radar was tested in the field in the spring 2017. Different sounding modes on the EM were tested in different types of subsurface geology on Svalbard. Deep soundings were performed on polythermal glaciers down to a couple of hundred meters. Shallow soundings were used to map a ground water table in the firn area of a glacier. A combination of deep and shallow soundings was used to image buried ice under a sedimentary layer of a couple of meters. Subsurface sedimentary layers were imaged down to more than 20 meters in sand stone permafrost. This presentation will give an overview of the RIMFAX investigation, describe the development of the radar system, and show results from field tests of the radar.

  18. Results of the 1000 Hour Rotary Microfilter Endurance Test

    International Nuclear Information System (INIS)

    Herman, D.

    2010-01-01

    During operation, a primary concern is lifetime of the mechanical seal. Leakage from main shaft mechanical seal is expected to be first indication of wear on rotary filter but will not be the ultimate failure of the filter. Initial clearance inadequate to support thermal expansion resulted in initial scarring of journal. Tolerances adjusted and no journal issues were found during 1000 hour test. Disassembly and inspection of the rotary joint seals showed no unusual wear. No leakage observed during test. Total operation time over 1500 hours. Test summary successfully demonstrated: (1) Filtration of a 'challenging' SRS simulant up to 15 wt % insoluble solids in a 5.6 M salt simulant; (2) Sludge washing; (3) In-situ acid cleaning with dilute acid; (4) Over 1000 hours of operation on new journal material; and (5) Over 1500 hours of operation on all seals. The filter out lasted: 2 air compressors, 2 power outages (one planned), 2 chillers, 1 fire, 1 electrical breaker and 1 feed pump seal.

  19. Radioactive Testing Results in Support of the In-Tank Precipitation Facility - Filtrate Test

    International Nuclear Information System (INIS)

    Hobbs, D.T.

    1998-01-01

    This report documents results investigating the decomposition of excess NaTPB in presence of filtrate from one of the Cycle I Demonstration tests, fulfilling a request by CST Engineering and the ITP Flow Sheet Team

  20. The Space Station Photovoltaic Panels Plasma Interaction Test Program: Test plan and results

    Science.gov (United States)

    Nahra, Henry K.; Felder, Marian C.; Sater, Bernard L.; Staskus, John V.

    1989-01-01

    The Plasma Interaction Test performed on two space station solar array panels is addressed. This includes a discussion of the test requirements, test plan, experimental set-up, and test results. It was found that parasitic current collection was insignificant (0.3 percent of the solar array delivered power). The measured arcing threshold ranged from -210 to -457 V with respect to the plasma potential. Furthermore, the dynamic response of the panels showed the panel time constant to range between 1 and 5 microsec, and the panel capacitance to be between .01 and .02 microF.

  1. The Space Station photovoltaic panels plasma interaction test program - Test plan and results

    Science.gov (United States)

    Nahra, Henry K.; Felder, Marian C.; Sater, Bernard L.; Staskus, John V.

    1990-01-01

    The plasma Interaction Test performed on two space station solar array panels is addressed. This includes a discussion of the test requirements, test plan, experimental set-up, and test results. It was found that parasitic current collection was insignificant (0.3 percent of the solar array delivered power). The measured arcing threshold ranged from -210 to -457 V with respect to the plasma potential. Furthermore, the dynamic response of the panels showed the panel time constant to range between 1 and 5 microsec, and the panel capacitance to be between .01 and .02 microF.

  2. Results from laboratory and field testing of nitrate measuring spectrophotometers

    Science.gov (United States)

    Snazelle, Teri T.

    2015-01-01

    Five ultraviolet (UV) spectrophotometer nitrate analyzers were evaluated by the U.S. Geological Survey (USGS) Hydrologic Instrumentation Facility (HIF) during a two-phase evaluation. In Phase I, the TriOS ProPs (10-millimeter (mm) path length), Hach NITRATAX plus sc (5-mm path length), Satlantic Submersible UV Nitrate Analyzer (SUNA, 10-mm path length), and S::CAN Spectro::lyser (5-mm path length) were evaluated in the HIF Water-Quality Servicing Laboratory to determine the validity of the manufacturer's technical specifications for accuracy, limit of linearity (LOL), drift, and range of operating temperature. Accuracy specifications were met in the TriOS, Hach, and SUNA. The stock calibration of the S::CAN required two offset adjustments before the analyzer met the manufacturer's accuracy specification. Instrument drift was observed only in the S::CAN and was the result of leaching from the optical path insert seals. All tested models, except for the Hach, met their specified LOL in the laboratory testing. The Hach's range was found to be approximately 18 milligrams nitrogen per liter (mg-N/L) and not the manufacturer-specified 25 mg-N/L. Measurements by all of the tested analyzers showed signs of hysteresis in the operating temperature tests. Only the SUNA measurements demonstrated excessive noise and instability in temperatures above 20 degrees Celsius (°C). The SUNA analyzer was returned to the manufacturer at the completion of the Phase II field deployment evaluation for repair and recalibration, and the performance of the sensor improved significantly.

  3. Tc-99 Adsorption on Selected Activated Carbons - Batch Testing Results

    Energy Technology Data Exchange (ETDEWEB)

    Mattigod, Shas V.; Wellman, Dawn M.; Golovich, Elizabeth C.; Cordova, Elsa A.; Smith, Ronald M.

    2010-12-01

    CH2M HILL Plateau Remediation Company (CHPRC) is currently developing a 200-West Area groundwater pump-and-treat system as the remedial action selected under the Comprehensive Environmental Response, Compensation, and Liability Act Record of Decision for Operable Unit (OU) 200-ZP-1. This report documents the results of treatability tests Pacific Northwest National Laboratory researchers conducted to quantify the ability of selected activated carbon products (or carbons) to adsorb technetium-99 (Tc-99) from 200-West Area groundwater. The Tc-99 adsorption performance of seven activated carbons (J177601 Calgon Fitrasorb 400, J177606 Siemens AC1230AWC, J177609 Carbon Resources CR-1240-AW, J177611 General Carbon GC20X50, J177612 Norit GAC830, J177613 Norit GAC830, and J177617 Nucon LW1230) were evaluated using water from well 299-W19-36. Four of the best performing carbons (J177606 Siemens AC1230AWC, J177609 Carbon Resources CR-1240-AW, J177611 General Carbon GC20X50, and J177613 Norit GAC830) were selected for batch isotherm testing. The batch isotherm tests on four of the selected carbons indicated that under lower nitrate concentration conditions (382 mg/L), Kd values ranged from 6,000 to 20,000 mL/g. In comparison. Under higher nitrate (750 mg/L) conditions, there was a measureable decrease in Tc-99 adsorption with Kd values ranging from 3,000 to 7,000 mL/g. The adsorption data fit both the Langmuir and the Freundlich equations. Supplemental tests were conducted using the two carbons that demonstrated the highest adsorption capacity to resolve the issue of the best fit isotherm. These tests indicated that Langmuir isotherms provided the best fit for Tc-99 adsorption under low nitrate concentration conditions. At the design basis concentration of Tc 0.865 µg/L(14,700 pCi/L), the predicted Kd values from using Langmuir isotherm constants were 5,980 mL/g and 6,870 mL/g for for the two carbons. These Kd values did not meet the target Kd value of 9,000 mL/g. Tests

  4. Postural control in blind subjects.

    Science.gov (United States)

    Soares, Antonio Vinicius; Oliveira, Cláudia Silva Remor de; Knabben, Rodrigo José; Domenech, Susana Cristina; Borges Junior, Noe Gomes

    2011-12-01

    To analyze postural control in acquired and congenitally blind adults. A total of 40 visually impaired adults participated in the research, divided into 2 groups, 20 with acquired blindness and 20 with congenital blindness - 21 males and 19 females, mean age 35.8 ± 10.8. The Brazilian version of Berg Balance Scale and the motor domain of functional independence measure were utilized. On Berg Balance Scale the mean for acquired blindness was 54.0 ± 2.4 and 54.4 ± 2.5 for congenitally blind subjects; on functional independence measure the mean for acquired blind group was 87.1 ± 4.8 and 87.3 ± 2.3 for congenitally blind group. Based upon the scale used the results suggest the ability to control posture can be developed by compensatory mechanisms and it is not affected by visual loss in congenitally and acquired blindness.

  5. First irradiation test results of the ALICE SAMPA ASIC

    CERN Document Server

    Mahmood, Sohail Musa; Winje, Fredrik Lindseth; Velure, Arild

    2018-01-01

    With the continuous scaling of the CMOS technology, the CMOS circuits are considered to be more tolerant to Single event Latchup (SEL) effects due to the reduction in the supply voltages. This paper reports the results from SEL testing performed on the first two prototypes for the new readout ASIC (SAMPA). During RUN 3/RUN 4 at the Large Hadron Collider (LHC), the SAMPA chip will be used for the upgrade of read-out front end electronics of the ALICE (A Large Ion Collider Experiment) Time Projection Chamber (TPC) and Muon Chambers (MCH). The first prototype MPW1 and the second prototype V2 of the SAMPA chip were delivered in 2015 and 2016, respectively. The results are summarized from two different proton beam irradiation campaigns, conducted for SAMPA MPW1 and V2 prototypes at The Svedberg Laboratory (TSL) in Uppsala, and the Center of Advanced Radiation Technology (KVI) in Groningen, respectively.

  6. Aerodynamic and Acoustic Flight Test Results and Results for the Stratospheric Observatory for Infrared Astronomy

    Science.gov (United States)

    Cumming, Stephen B.; Smith, Mark S.; Cliatt, Larry J.; Frederick, Michael A.

    2014-01-01

    As part of the Stratospheric Observatory for Infrared Astronomy program, a 747SP airplane was modified to carry a 2.5-m telescope in the aft section of the fuselage. The resulting airborne observatory allows for observations above 99 percent of the water vapor in the atmosphere. The open cavity created by the modifications had the potential to significantly affect the airplane in the areas of aerodynamics and acoustics. Several series of flight tests were conducted to clear the operating envelope of the airplane for astronomical observations, planned to be performed between the altitudes of 35,000 ft and 45,000 ft. The flight tests were successfully completed. Cavity acoustics were below design limits, and the overall acoustic characteristics of the cavity were better than expected. The modification did have some effects on the stability and control of the airplane, but these effects were not significant. Airplane air data systems were not affected by the modifications. This paper describes the methods used to examine the aerodynamics and acoustic data from the flight tests and provides a discussion of the flight-test results in the areas of cavity acoustics, stability and control, and air data.

  7. Test results for cables used in nuclear power plants by a new environmental testing method

    International Nuclear Information System (INIS)

    Handa, Katsue; Fujimura, Shun-ichi; Hayashi, Toshiyasu; Takano, Keiji; Oya, Shingo

    1982-01-01

    In the nuclear power plants using PWRs or BWRs in Japan, environmental tests are provided, in which simulated LOCA conditions are considered so as to conform with Japanese conditions, and many cables which passed these tests are presently employed. Lately, the new environmental testing, in which a credible accident called MSLB (main steam line breakage) is taken into account, is investigated in PWR nuclear power plants, besides LOCA. This paper reports on the results of evaluating some PWR cables for this new environmental testing conditions. The several cables tested were selected out of PH cables (fire-retardant, ethylene propylene rubber insulated, chlorosulfonated polyethylene sheathed cables) as the cables for safety protecting circuits and to be used in containment vessels where the cables are to be exposed to severe environmental test conditions of 2 x 10 8 Rad γ-irradiation and simulated LOCA. All these cables have been accepted after the vertical tray burning test provided in the IEEE Standard 383. The new testing was carried out by sequentially applying thermal deterioration, γ-irradiation, and the exposure to steam (twice 300 s exposures to 190 deg C superheated steam). After completing each step, tensile strength, elongation, insulation resistance and breakdown voltage were measured, respectively. Every cable tested showed satisfactory breakdown voltage after the exposure to steam, thus it was decided to be acceptable. In future, it is required to investigate the influence of the rate of temperature rise on the cable to be tested in MSLB simulation. (Wakatsuki, Y.)

  8. Relationships Among the Knowledge, Efficacy, and Practices Instrument, Color-Blind Racial Attitudes Scale, Deamonte Driver Survey, and Defining Issues Test 2.

    Science.gov (United States)

    Behar-Horenstein, Linda S; Garvan, Cynthia W

    2016-03-01

    Concordance studies indicate the degree to which instruments measure the same or similar constructs or something different. The aims of this study were to identify the factor structure of the Deamonte Driver Survey and determine the relationship between the Deamonte Driver (a measure of social class stereotyping), the Defining Issues Test 2 (DIT2; a measure of ethical sensitivity), the Color-Blind Racial Attitudes Scale (CoBRAS; a measure of racial stereotyping), and the Knowledge, Efficacy, and Practices Instrument (KEPI; a measure of cultural competence). The results showed a three-factor solution for the Deamonte Driver Survey and significant relationships between CoBRAS and DIT2 subscales and between CoBRAS and Deamonte Driver subscales. Significant relationships between the measures and exploratory variables, underrepresented minority status, age, citizenship, marital status, political stance, English as a first language, and gender were found. The lack of a significant relationship between the KEPI and Deamonte Driver, DIT2, or CoBRAS subscales suggests that the KEPI is measuring a unique construct. These findings showed how these scales contributed to the assessment of cultural competence among dental students and faculty.

  9. Lidocaine patch (5%) is no more potent than placebo in treating chronic back pain when tested in a randomised double blind placebo controlled brain imaging study

    Science.gov (United States)

    2012-01-01

    Background The 5% Lidocaine patch is used for treating chronic neuropathic pain conditions such as chronic back pain (CBP), diabetic neuropathy and complex regional pain syndrome, but is effective in a variable proportion of patients. Our lab has reported that this treatment reduces CBP intensity and associated brain activations when tested in an open labelled preliminary study. Notably, effectiveness of the 5% Lidocaine patch has not been tested against placebo for treating CBP. In this study, effectiveness of the 5% Lidocaine patch was compared with placebo in 30 CBP patients in a randomised double-blind study where 15 patients received 5% Lidocaine patches and the remaining patients received placebo patches. Functional MRI was used to identify brain activity for fluctuations of spontaneous pain, at baseline and at two time points after start of treatment (6 hours and 2 weeks). Results There was no significant difference between the treatment groups in either pain intensity, sensory and affective qualities of pain or in pain related brain activation at any time point. However, 50% patients in both the Lidocaine and placebo arms reported a greater than 50% decrease in pain suggesting a marked placebo effect. When tested against an untreated CBP group at similar time points, the patch treated subjects showed significantly greater decrease in pain compared to the untreated group (n = 15). Conclusions These findings suggest that although the 5% Lidocaine is not better than placebo in its effectiveness for treating pain, the patch itself induces a potent placebo effect in a significant proportion of CBP patients. PMID:22531485

  10. School results and access test results as indicators of first-year performance at university

    Directory of Open Access Journals (Sweden)

    A Bothma

    2004-06-01

    Full Text Available The goals set by the National Plan for Higher Education, the fact that many schools are still severely disadvantaged as well as far-reaching changes in the school system demand that South African universities urgently reconsider their admission procedures. Redesigning admission procedures calls for a thorough understanding of the interrelationships between school marks, results in existing access tests and first-year university performance. These interrelationships were statistically investigated in the case of the 1999, 2000 and 2001 intake groups, who were compelled to write access tests before being admitted to Stellenbosch University. The results of this investigation confirm an alarming degree of unpreparedness among many prospective students regarding what is expected of them at university. This is aggravated by school marks creating a totally unrealistic expectation of performance in the first year at university. It is emphasised that schools and authorities dealing with admission of prospective students at universities should be cognisant of the findings reported here. Furthermore, the statistical analyses demonstrate several novel techniques for investigating the interrelationship between school marks, access test results and university performance.

  11. Polygraph Test Results Assessment by Regression Analysis Methods

    Directory of Open Access Journals (Sweden)

    K. A. Leontiev

    2014-01-01

    Full Text Available The paper considers a problem of defining the importance of asked questions for the examinee under judicial and psychophysiological polygraph examination by methods of mathematical statistics. It offers the classification algorithm based on the logistic regression as an optimum Bayesian classifier, considering weight coefficients of information for the polygraph-recorded physiological parameters with no condition for independence of the measured signs.Actually, binary classification is executed by results of polygraph examination with preliminary normalization and standardization of primary results, with check of a hypothesis that distribution of obtained data is normal, as well as with calculation of coefficients of linear regression between input values and responses by method of maximum likelihood. Further, the logistic curve divided signs into two classes of the "significant" and "insignificant" type.Efficiency of model is estimated by means of the ROC analysis (Receiver Operator Characteristics. It is shown that necessary minimum sample has to contain results of 45 measurements at least. This approach ensures a reliable result provided that an expert-polygraphologist possesses sufficient qualification and follows testing techniques.

  12. Results of industrial tests of carbonate additive to fuel oil

    Science.gov (United States)

    Zvereva, E. R.; Dmitriev, A. V.; Shageev, M. F.; Akhmetvalieva, G. R.

    2017-08-01

    Fuel oil plays an important role in the energy balance of our country. The quality of fuel oil significantly affects the conditions of its transport, storage, and combustion; release of contaminants to atmosphere; and the operation of main and auxiliary facilities of HPPs. According to the Energy Strategy of Russia for the Period until 2030, the oil-refining ratio gradually increases; as a result, the fraction of straight-run fuel oil in heavy fuel oils consistently decreases, which leads to the worsening of performance characteristics of fuel oil. Consequently, the problem of the increase in the quality of residual fuel oil is quite topical. In this paper, it is suggested to treat fuel oil by additives during its combustion, which would provide the improvement of ecological and economic indicators of oil-fired HPPs. Advantages of this method include simplicity of implementation, low energy and capital expenses, and the possibility to use production waste as additives. In the paper, the results are presented of industrial tests of the combustion of fuel oil with the additive of dewatered carbonate sludge, which is formed during coagulation and lime treatment of environmental waters on HPPs. The design of a volume delivery device is developed for the steady additive input to the boiler air duct. The values are given for the main parameters of the condition of a TGM-84B boiler plant. The mechanism of action of dewatered carbonate sludge on sulfur oxides, which are formed during fuel oil combustion, is considered. Results of industrial tests indicate the decrease in the mass fraction of discharged sulfur oxides by 36.5%. Evaluation of the prevented damage from sulfur oxide discharged into atmospheric air shows that the combustion of the fuel oil of 100 brand using carbonate sludge as an additive (0.1 wt %) saves nearly 6 million rubles a year during environmental actions at the consumption of fuel oil of 138240 t/year.

  13. Test Results and Comparison of Triaxial Strength Testing of Waste Isolation Pilot Plant Clean Salt

    Energy Technology Data Exchange (ETDEWEB)

    Buchholz, Stuart A. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2016-12-01

    This memorandum documents laboratory thermomechanical triaxial strength testing of Waste Isolation Pilot Plant (WIPP) clean salt. The limited study completed independent, adjunct laboratory tests in the United States to assist in validating similar testing results being provided by the German facilities. The testing protocol consisted of completing confined triaxial, constant strain rate strength tests of intact WIPP clean salt at temperatures of 25°C and 100°C and at multiple confining pressures. The stratigraphy at WIPP also includes salt that has been labeled “argillaceous.” The much larger test matrix conducted in Germany included both the so-called clean and argillaceous salts. When combined, the total database of laboratory results will be used to develop input parameters for models, assess adequacy of existing models, and predict material behavior. These laboratory studies are also consistent with the goals of the international salt repository research program. The goal of this study was to complete a subset of a test matrix on clean salt from the WIPP undertaken by German research groups. The work was performed at RESPEC in Rapid City, South Dakota. A rigorous Quality Assurance protocol was applied, such that corroboration provides the potential of qualifying all of the test data gathered by German research groups.

  14. MATISSE: alignment, integration, and test phase first results

    Science.gov (United States)

    Allouche, F.; Robbe-Dubois, S.; Lagarde, S.; Cruzalèbes, P.; Antonelli, P.; Bresson, Y.; Fantei-Caujolle, Y.; Marcotto, A.; Morel, S.; Beckmann, U.; Bettonvil, F.; Berio, Ph.; Heininger, M.; Lehmitz, M.; Agocs, T.; Brast, R.; Elswijk, E.; Ives, D.; Meixner, K.; Laun, W.; Mellein, M.; Neumann, U.; Bailet, C.; Clausse, J.-M.; Matter, A.; Meilland, A.; Millour, F.; Petrov, R. G.; Accardo, M.; Bristow, P.; Frahm, R.; Glindemann, A.; Gonzáles Herrera, J.-C.; Lizon, J.-L.; Schöller, M.; Graser, U.; Jaffe, W.; Lopez, B.

    2016-08-01

    MATISSE (Multi AperTure mid-Infrared SpectroScopic Experiment) is the spectro-interferometer for the VLTI of the European Southern Observatory, operating in near and mid-infrared, and combining up to four beams from the unit or the auxiliary telescopes. MATISSE will offer new breakthroughs in the study of circumstellar environments by allowing the multispectral mapping of the material distribution, the gas and essentially the dust. The instrument consists in a warm optical system (WOP) accepting four optical beams and relaying them after a dichroic splitting (for the L and M- and N- spectral bands) to cold optical benches (COB) located in two separate cryostats. The Observatoire de la Côte d'Azur is in charge of the WOP providing the spectral band separation, optical path equalization and modulation, pupil positioning, beam anamorphosis, beam commutation, and calibration. NOVA-ASTRON is in charge of the COB providing the functions of beam selection, reduction of thermal background emission, spatial filtering, pupil transfer, photometry and interferometry splitting, additional beam anamorphosis, spectral filtering, polarization selection, image dispersion, and image combination. The Max Planck Institut für Radio Astronomie is in charge of the operation and performance validation of the two detectors, a HAWAII-2RG from Teledyne for the L- and M- bands and a Raytheon AQUARIUS for the N-band. Both detectors are provided by ESO. The Max Planck Institut für Astronomie is in charge of the electronics and the cryostats for which the requirements on space limitations and vibration stability resulted on very specific and stringent decisions on the design. The integration and test of the COB: the two cryogenic systems, including the cold benches and the detectors, have been conducted at MPIA in parallel with the integration of the WOP at OCA. At the end of 2014, the complete instrument was integrated at OCA. Following this integration, a period of interface and alignment

  15. Fission Surface Power Technology Demonstration Unit Test Results

    Science.gov (United States)

    Briggs, Maxwell H.; Gibson, Marc A.; Geng, Steven M.; Sanzi, James L.

    2016-01-01

    The Fission Surface Power (FSP) Technology Demonstration Unit (TDU) is a system-level demonstration of fission power technology intended for use on manned missions to Mars. The Baseline FSP systems consists of a 190 kWt UO2 fast-spectrum reactor cooled by a primary pumped liquid metal loop. This liquid metal loop transfers heat to two intermediate liquid metal loops designed to isolate fission products in the primary loop from the balance of plant. The intermediate liquid metal loops transfer heat to four Stirling Power Conversion Units (PCU), each of which produce 12 kWe (48 kW total) and reject waste heat to two pumped water loops, which transfer the waste heat to titanium-water heat pipe radiators. The FSP TDU simulates a single leg of the baseline FSP system using an electrically heater core simulator, a single liquid metal loop, a single PCU, and a pumped water loop which rejects the waste heat to a Facility Cooling System (FCS). When operated at the nominal operating conditions (modified for low liquid metal flow) during TDU testing the PCU produced 8.9 kW of power at an efficiency of 21.7 percent resulting in a net system power of 8.1 kW and a system level efficiency of 17.2 percent. The reduction in PCU power from levels seen during electrically heated testing is the result of insufficient heat transfer from the NaK heater head to the Stirling acceptor, which could not be tested at Sunpower prior to delivery to the NASA Glenn Research Center (GRC). The maximum PCU power of 10.4 kW was achieved at the maximum liquid metal temperature of 875 K, minimum water temperature of 350 K, 1.1 kg/s liquid metal flow, 0.39 kg/s water flow, and 15.0 mm amplitude at an efficiency of 23.3 percent. This resulted in a system net power of 9.7 kW and a system efficiency of 18.7 percent.

  16. Results of conductor testing in SULTAN a review

    CERN Document Server

    Wesche, R; Bruzzone, P; Calvi, M; Cau, F; Herzog, R; Marinucci, C; Stepanov, B

    2009-01-01

    In the last few years, the DC performance of a large number of sub- and full-size NbTi as well as Nb3Sn cablein- conduit (CIC) conductors was tested in the SULTAN facility of CRPP. The “potential” DC performance of various CIC conductors was estimated from the measured strand data. In the present work, the DC performance of CIC conductors, measured in SULTAN, is compared with this “potential” DC performance. The DC performance of NbTi sub- and full size CIC conductors has been found to be in good agreement with the “potential” conductor performance. For Nb3Sn CIC conductors, the situation is more complex because of the strain sensitivity of the critical current. Evidence for strand damage, caused by the large Lorentz forces, has been found in Nb3Sn subsize conductors. Finally, a summary of the results of the tests of the ITER-TF Nb3Sn conductors is provided. Again the measured DC performance is compared to the "potential" performance.

  17. Ground Operations Demonstration Unit for Liquid Hydrogen Initial Test Results

    Science.gov (United States)

    Notardonato, W. U.; Johnson, W. L.; Swanger, A. M.; Tomsik, T.

    2015-01-01

    NASA operations for handling cryogens in ground support equipment have not changed substantially in 50 years, despite major technology advances in the field of cryogenics. NASA loses approximately 50% of the hydrogen purchased because of a continuous heat leak into ground and flight vessels, transient chill down of warm cryogenic equipment, liquid bleeds, and vent losses. NASA Kennedy Space Center (KSC) needs to develop energy-efficient cryogenic ground systems to minimize propellant losses, simplify operations, and reduce cost associated with hydrogen usage. The GODU LH2 project has designed, assembled, and started testing of a prototype storage and distribution system for liquid hydrogen that represents an advanced end-to-end cryogenic propellant system for a ground launch complex. The project has multiple objectives including zero loss storage and transfer, liquefaction of gaseous hydrogen, and densification of liquid hydrogen. The system is unique because it uses an integrated refrigeration and storage system (IRAS) to control the state of the fluid. This paper will present and discuss the results of the initial phase of testing of the GODU LH2 system.

  18. Drop Test Results of CRDM under Seismic Loads

    International Nuclear Information System (INIS)

    Choi, Myoung-Hwan; Cho, Yeong-Garp; Kim, Gyeong-Ho; Sun, Jong-Oh; Huh, Hyung

    2016-01-01

    This paper describes the test results to demonstrate the drop performance of CRDM under seismic loads. The top-mounted CRDM driven by the stepping motor for Jordan Research and Training Reactor (JRTR) has been developed in KAERI. The CRDM for JRTR has been optimized by the design improvement based on that of the HANARO. It is necessary to verify the drop performance under seismic loads such as operating basis earthquake (OBE) and safe shutdown earthquake (SSE). Especially, the CAR drop times are important data for the safety analysis. confirm the drop performance under seismic loads. The delay of drop time at Rig no. 2 due to seismic loads is greater than that at Rig no. 3. The total pure drop times under seismic loads are estimated as 1.169 and 1.855, respectively

  19. Business jet approach noise abatement techniques - Flight test results

    Science.gov (United States)

    Putnam, T. W.; Burcham, F. W.

    1976-01-01

    Operational techniques for reducing approach noise from business jet aircraft were evaluated in flight by measuring the noise generated by five such aircraft during modified approaches. Approaches with 4-deg glide slopes were approximately 4.0 EPNdB quieter than approaches with standard 3-deg glide slopes. Noise reductions for low-drag 3-deg approaches varied widely among the airplanes tested; the fleet-weighted reduction was 8.5 EPNdB. Two-segment approaches resulted in noise reductions of 7.0 EPNdB to 8.5 EPNdB 3 nautical miles and 5 nautical miles from touchdown. Pilot workload increased progressively for the 4-deg, low-drag 3-deg, and two-segment approach.

  20. Stirling cryocooler test results and design model verification

    International Nuclear Information System (INIS)

    Shimko, M.A.; Stacy, W.D.; McCormick, J.A.

    1990-01-01

    This paper reports on progress in developing a long-life Stirling cycle cryocooler for space borne applications. It presents the results from tests on a preliminary breadboard version of the cryocooler used to demonstrate the feasibility of the technology and to validate the regenerator design code used in its development. This machine achieved a cold-end temperature of 65 K while carrying a 1/2 Watt cooling load. The basic machine is a double-acting, flexure-bearing, split Stirling design with linear electromagnetic drives for the expander and compressors. Flat metal diaphragms replace pistons for both sweeping and sealing the machine working volumes. In addition, the double-acting expander couples to a laminar-channel counterflow recuperative heat exchanger for regeneration. A PC compatible design code was developed for this design approach that calculates regenerator loss including heat transfer irreversibilities, pressure drop, and axial conduction in the regenerator walls

  1. Postirradiation examination results for the irradiation effects scoping test 1

    International Nuclear Information System (INIS)

    Mehner, A.S.; Quapp, W.J.; Goetzmann, O.; Hobbins, R.R.

    1976-09-01

    A zircaloy-clad UO 2 fuel rod was operated above its critical heat flux within the in-pile test loop of the Power Burst Facility and later examined in the hot cells. The results of the postirradiation examinations are presented in this report. A Zr-UO 2 reaction at the fuel-cladding interface embrittled nearly as much of the cladding wall thickness as the Zr-water reaction on the exterior. Data on both the internal and external reactions, and cladding and fuel microstructures, are presented. Cladding embrittlement and rod failure are compared with several rod fragmentation criteria, and conclusions concerning fuel rod failure propagation in a power reactor system are made

  2. Postirradiation examination results for the irradiation effects scoping test 1

    Energy Technology Data Exchange (ETDEWEB)

    Mehner, A.S.; Quapp, W.J.; Goetzmann, O.; Hobbins, R.R.

    1976-09-01

    A zircaloy-clad UO/sub 2/ fuel rod was operated above its critical heat flux within the in-pile test loop of the Power Burst Facility and later examined in the hot cells. The results of the postirradiation examinations are presented in this report. A Zr-UO/sub 2/ reaction at the fuel-cladding interface embrittled nearly as much of the cladding wall thickness as the Zr-water reaction on the exterior. Data on both the internal and external reactions, and cladding and fuel microstructures, are presented. Cladding embrittlement and rod failure are compared with several rod fragmentation criteria, and conclusions concerning fuel rod failure propagation in a power reactor system are made.

  3. Acoustic conditions in open plan offices – Pilot test results

    Directory of Open Access Journals (Sweden)

    Witold Mikulski

    2016-10-01

    Full Text Available Background: The main source of noise in open plan office are conversations. Office work standards in such premises are attained by applying specific acoustic adaptation. This article presents the results of pilot tests and acoustic evaluation of open space rooms. Material and Methods: Acoustic properties of 6 open plan office rooms were the subject of the tests. Evaluation parameters, measurement methods and criterial values were adopted according to the following standards: PN-EN ISO 3382- 3:2012, PN-EN ISO 3382-2:2010, PN-B-02151-4:2015-06 and PN-B-02151-3:2015-10. Results: The reverberation time was 0.33– 0.55 s (maximum permissible value in offices – 0.6 s; the criterion was met, sound absorption coefficient in relation to 1 m2 of the room’s plan was 0.77–1.58 m2 (minimum permissible value – 1.1 m2; 2 out of 6 rooms met the criterion, distraction distance was 8.5–14 m (maximum permissible value – 5 m; none of the rooms met the criterion, A-weighted sound pressure level of speech at a distance of 4 m was 43.8–54.7 dB (maximum permissible value – 48 dB; 2 out of 6 rooms met the criterion, spatial decay rate of the speech was 1.8–6.3 dB (minimum permissible value – 7 dB; none of the rooms met the criterion. Conclusions: Standard acoustic treatment, containing sound absorbing suspended ceiling, sound absorbing materials on the walls, carpet flooring and sound absorbing workplace barriers, is not sufficient. These rooms require specific advanced acoustic solutions. Med Pr 2016;67(5:653–662

  4. Influence of blood lipids on global coagulation test results.

    Science.gov (United States)

    Kim, Jung-Ah; Kim, Ji-Eun; Song, Sang Hoon; Kim, Hyun Kyung

    2015-01-01

    High levels of blood lipids have been associated with high levels of coagulation factors. We investigated whether blood lipids influence the results of global coagulation tests, including prothrombin time (PT), activated partial thromboplastin time (aPTT), and thrombin generation assay (TGA). PT, aPTT, and TGA, along with procoagulant and anticoagulant factors, were measured in 488 normal individuals. Vitamin K status was assessed with prothrombin-induced by vitamin K absence-II (PIVKA-II). The procoagulant factors II, VII, IX, X, and XI and anticoagulant factors protein C and protein S showed significant correlations with triglyceride, and the procoagulant factors II, V, VII, IX, X, XI, and XII and anticoagulant factors antithrombin and protein C correlated with total cholesterol. There were no correlations of blood lipid levels with PIVKA-II levels. Subjects with high triglyceride levels (≥200 mg/dL) showed shorter PT values than those with lower triglyceride levels. However, aPTT value was not changed in terms of blood lipid levels. In both 1 and 5 pM tissue factor-induced TGAs, subjects in the high-triglyceride or high-cholesterol groups (≥240 mg/dL) had high levels of lag time, time-to-peak, and endogenous thrombin potential. Total cholesterol was a significant determinant of PT and TGA values. High blood lipids were related with increased coagulation activity in a normal population. Our findings are expected to help interpret the global coagulation test results in individuals with high lipid levels.

  5. Nonlinear Analysis and Preliminary Testing Results of a Hybrid Wing Body Center Section Test Article

    Science.gov (United States)

    Przekop, Adam; Jegley, Dawn C.; Rouse, Marshall; Lovejoy, Andrew E.; Wu, Hsi-Yung T.

    2015-01-01

    A large test article was recently designed, analyzed, fabricated, and successfully tested up to the representative design ultimate loads to demonstrate that stiffened composite panels with through-the-thickness reinforcement are a viable option for the next generation large transport category aircraft, including non-conventional configurations such as the hybrid wing body. This paper focuses on finite element analysis and test data correlation of the hybrid wing body center section test article under mechanical, pressure and combined load conditions. Good agreement between predictive nonlinear finite element analysis and test data is found. Results indicate that a geometrically nonlinear analysis is needed to accurately capture the behavior of the non-circular pressurized and highly-stressed structure when the design approach permits local buckling.

  6. Lemborexant, A Dual Orexin Receptor Antagonist (DORA) for the Treatment of Insomnia Disorder: Results From a Bayesian, Adaptive, Randomized, Double-Blind, Placebo-Controlled Study.

    Science.gov (United States)

    Murphy, Patricia; Moline, Margaret; Mayleben, David; Rosenberg, Russell; Zammit, Gary; Pinner, Kate; Dhadda, Shobha; Hong, Quan; Giorgi, Luigi; Satlin, Andrew

    2017-11-15

    To identify dose(s) of lemborexant that maximize insomnia treatment efficacy while minimizing next-morning residual sleepiness and evaluate lemborexant effects on polysomnography (PSG) measures (sleep efficiency [SE], latency to persistent sleep [LPS], and wake after sleep onset [WASO]) at the beginning and end of treatment. Adults and elderly subjects with insomnia disorder per the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition were enrolled in a multicenter, randomized, double-blind, placebo-controlled, Bayesian, adaptive, parallel-group study, receiving lemborexant (1, 2.5, 5, 10, 15, 25 mg) or placebo for 15 nights. Efficacy assessments included a utility function that combined efficacy (SE) and safety (residual morning sleepiness as measured by Karolinska Sleepiness Scale [KSS]), PSG measures, and sleep diary. Safety assessments included KSS, Digit Symbol Substitution Test, computerized reaction time tests, and adverse events (AEs). A total of 616 subjects were screened; 291 were randomized. Baseline characteristics were similar between lemborexant groups and placebo (∼63% female, median age: 49.0 years). The study was stopped for early success after the fifth interim analysis when the 15-mg dose met utility index/KSS criteria for success; 3 other doses also met the criteria. Compared with placebo, subjects showed significant improvements in SE, subjective SE, LPS, and subjective sleep onset latency at the beginning and end of treatment for lemborexant doses ≥ 5 mg ( P 1 mg. AEs, mostly mild to moderate, included dose-related somnolence. Lemborexant doses ranging from 2.5-10 mg provided efficacy for the treatment of insomnia while minimizing next-morning residual sleepiness. Title: A Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group, Bayesian Adaptive Randomization Design, Dose Response Study of the Efficacy of E2006 in Adults and Elderly Subjects With Chronic Insomnia; URL: https://clinicaltrials.gov/ct2/show

  7. Bioequivalence of a biosimilar enoxaparin sodium to Clexane® after single 100 mg subcutaneous dose: results of a randomized, double-blind, crossover study in healthy volunteers

    Directory of Open Access Journals (Sweden)

    Martínez González J

    2018-03-01

    Full Text Available Javier Martínez González, Mayte Monreal, Ignacio Ayani Almagia, Jordi Llaudó Garín, Lourdes Ochoa Díaz de Monasterioguren, Ibón Gutierro Adúriz R&D Department, Laboratorios Farmacéuticos Rovi S.A., Madrid, Spain Purpose: To demonstrate the pharmacokinetic/pharmacodynamic (PK/PD equivalence of a biosimilar enoxaparin to the reference drug, and to assess its safety and tolerability in healthy volunteers. Patients and methods: A randomized, double-blind, crossover, 2-sequence, single-dose study was conducted in healthy volunteers of both sexes. Participants were sequentially and randomly administered single subcutaneous injections of enoxaparin 100 mg manufactured by Rovi (test; Madrid, Spain and Clexane® (enoxaparin 100 mg manufactured by Sanofi, reference separated by a 1-week washout period. The primary PK/PD variables were maximum activity (Amax and area under the effect curve from time 0 to the last measured activity (T (AUEC0–T and AUEC from time 0 to infinity (AUEC0–inf of anti-FXa activity, and Amax and AUEC0–T of anti-FIIa activity. Secondary variables were Amax and AUEC0–T, AUEC0–inf of tissue factor pathway inhibitor, and the ratio of AUEC0–T anti-FXa to anti-FIIa activity. Biosimilarity would be shown when the 95% CI of the ratio of geometric least squares means (95% CI RGLSMs of primary PK/PD parameters fell within the standard range of bioequivalence, ie, 80%–125%.Results: The study sample consisted of 46 volunteers (33 males aged 18–44 years and with body mass index ranging from 19.0 to 31.1 kg/m2. Three subjects did not complete the study. The curves of anti-FXa, anti-FIIa and tissue factor pathway inhibitor activities corresponding to administration of the test and reference products were comparable. The 95% CI RGLSMs of Amax, AUEC0–T and AUEC0–inf for anti-FXa activity were 94.6%–105.9%, 99.8%–108.0% and 100.0%–108.6% respectively; Amax and AUEC0–T for anti-FIIa activity were 94.7%–112.6% and

  8. 'False-positive' and 'false-negative' test results in clinical urine drug testing.

    Science.gov (United States)

    Reisfield, Gary M; Goldberger, Bruce A; Bertholf, Roger L

    2009-08-01

    The terms 'false-positive' and 'false-negative' are widely used in discussions of urine drug test (UDT) results. These terms are inadequate because they are used in different ways by physicians and laboratory professionals and they are too narrow to encompass the larger universe of potentially misleading, inappropriate and unexpected drug test results. This larger universe, while not solely comprised of technically 'true' or 'false' positive or negative test results, presents comparable interpretive challenges with corresponding clinical implications. In this review, we propose the terms 'potentially inappropriate' positive or negative test results in reference to UDT results that are ambiguous or unexpected and subject to misinterpretation. Causes of potentially inappropriate positive UDT results include in vivo metabolic conversions of a drug, exposure to nonillicit sources of a drug and laboratory error. Causes of potentially inappropriate negative UDT results include limited assay specificity, absence of drug in the urine, presence of drug in the urine, but below established assay cutoff, specimen manipulation and laboratory error. Clinical UDT interpretation is a complicated task requiring knowledge of recent prescription, over-the-counter and herbal drug administration, drug metabolism and analytical sensitivities and specificities.

  9. The six blind men and the elephant: Are episodic memory tasks tests of different things or different tests of the same thing?

    Science.gov (United States)

    Cheke, Lucy G; Clayton, Nicola S

    2015-09-01

    The development of episodic memory in children has been of interest to researchers for more than a century. Current behavioral tests that have been developed to assess episodic memory differ substantially in their surface features. Therefore, it is possible that these tests are assessing different memory processes. In this study, 106 children aged 3 to 6 years were tested on four putative tests of episodic memory. Covariation in performance was investigated in order to address two conflicting hypotheses: (a) that the high level of difference between the tests will result in little covariation in performance despite their being designed to assess the same ability and (b) that the conceptual similarity of these tasks will lead to high levels of covariation despite surface differences. The results indicated a gradual improvement with age on all tests. Performances on many of the tests were related, but not after controlling for age. A principal component analysis found that a single principal component was able to satisfactorily fit the observed data. This principal component produced a marginally stronger correlation with age than any test alone. As such, it might be concluded that different tests of episodic memory are too different to be used in parallel. Nevertheless, if used together, these tests may offer a robust assessment of episodic memory as a complex multifaceted process. Copyright © 2015 The Authors. Published by Elsevier Inc. All rights reserved.

  10. Phosphate Management: FY2010 Results Of Phosphate Precipitation Tests

    International Nuclear Information System (INIS)

    Hay, M.; King, W.

    2011-01-01

    The Phosphate Management program seeks to develop treatment options for caustic phosphate solutions resulting from the caustic leaching of the bismuth phosphate sludge. The SRNL subtask investigated the precipitation of phosphate salts from caustic solutions through addition of fluoride and by crystallization. The scoping tests examined the: precipitation of phosphate by the addition of sodium fluoride to form the sodium fluorophosphate double salt, Na 7 F(PO 4 ) 2 · 19H 2 O, crystallization of phosphate by reducing the temperature of saturated phosphate solutions, and combinations of precipitation and crystallization. A simplified leachate simulant was used in the study produced by dissolving sodium phosphate in 1 M to 3.5 M sodium hydroxide solutions. The results show that all three processes; precipitation with sodium fluoride, crystallization, and combined precipitation/crystallization can be effective for removing large amounts of phosphate from solution. The combined process of precipitation/crystallization showed >90% removal of phosphate at all hydroxide concentrations when cooling a non-saturated phosphate solution from 65 C to 25 C. Based on the measured solubility of sodium phosphate, pH adjustment/caustic addition will also remove large amounts of phosphate from solution (>80%). For all three processes, the phosphate concentration in the caustic solution must be managed to keep the phosphate from becoming too concentrated and thereby potentially forming a solid mass of sodium phosphate after an effective phosphate removal process.

  11. Radiation pasteurization of poultry feed: Preliminary results of feeding tests

    International Nuclear Information System (INIS)

    Borsa, J.; Guenter, B.

    1992-01-01

    Feed used to rear farm animals for human consumption has often been implicated as a vehicle for dissemination of microbial pathogens that can adversely affect both animals or birds, and humans. Radiation pasteurization of animal feed to improve its microbiological quality should reduce the incidence of feed-borne infection in the herd or flock. This would result in safer food for the consumer, and improved economic performance of the production unit. This latter benefit is particularly important because it would directly offset the cost of treating the feed. The likelihood of occurrence, as well as the magnitude, of any improved economic performance in the herd or flock consuming the irradiated feed must be determined experimentally. Accordingly, short term feeding tests were carried out to determine the effect of radiation pasteurization of poultry feed on growth performance of young chicks. The results suggest that radiation pasteurization of poultry feed may have a beneficial effect on the feed conversion efficiency of the birds consuming that feed. 10 refs, 8 tabs

  12. A blast absorber test: measurement and model results

    NARCIS (Netherlands)

    Eerden, F.J.M. van der; Berg, F. van den; Hof, J. van 't; Arkel, E. van

    2006-01-01

    A blast absorber test was conducted at the Aberdeen Test Centre from 13 to 17 June 2005. The test was set up to determine the absorbing and shielding effect of a gravel pile, of 1.5 meters high and 15 by 15 meters wide, on blasts from large weapons: e.g. armor, artillery or demolition. The blast was

  13. Test results on systems developed for SST-1 tokamak

    International Nuclear Information System (INIS)

    Bora, D.

    2003-01-01

    used for heating the plasma while lower hybrid waves will be used for non inductive current drive (LHCD). A Neutral Beam Injection (NBI) with peak power of 0.8 MW with variable beam energy in range of 10-80 keV will be used as additional auxiliary heating system. A number of proto-types for various critical components have confirmed the fabrication methodology. The fabrication of most of the subsystems is nearing completion and many components have already been accepted at site. Erection and installation of the base of the mechanical structure has already been initiated in the SST hall. This paper reports on the results of the tests on various prototypes and actual components to be used on SST-1 for various subsystems. (author)

  14. NOx Abatement Pilot Plant 90-day test results report

    International Nuclear Information System (INIS)

    McCray, J.A.; Boardman, R.D.

    1991-01-01

    High-level radioactive liquid wastes produced during nuclear fuel reprocessing at the Idaho Chemical Processing Plant are calcined in the New Waste Calcining Facility (NWCF) to provide both volume reduction and a more stable waste form. Because a large component of the HLW is nitric acid, high levels of oxides of nitrogen (NO x ) are produced in the process and discharged to the environment via the calciner off-gas. The NO x abatement program is required by the new Fuel Processing Restoration (FPR) project permit to construct to reduce NO x emissions from the NWCF. Extensive research and development has indicated that the selective catalytic reduction (SCR) process is the most promising technology for treating the NWCF off-gas. Pilot plant tests were performed to determine the compatibility of the SCR process with actual NWCF off-gas. Test results indicate that the SCR process is a viable method for abating the NO x from the NWCF off-gas. Reduction efficiencies over 95% can be obtained, with minimal amounts of ammonia slip, provided favorable operating conditions exist. Two reactors operated with series flow will provide optimum reduction capabilities. Typical operation should be performed with a first reactor stage gas space velocity of 20,000 hr -1 and an inlet temperature of 320 degrees C. The first stage exhaust NO x concentration will then dictate the parameter settings for the second stage. Operation should always strive for a peak reactor temperature of 520 degrees C in both reactors, with minimal NH 3 slip from the second reactor. Frequent fluctuations in the NWCF off-gas NO x concentration will require a full-scale reduction facility that is versatile and quick-responding. Sudden changes in NWCF off-gas NO x concentrations will require quick detection and immediate response to avoid reactor bed over-heating and/or excessive ammonia slip

  15. Automated Critical Peak Pricing Field Tests: Program Descriptionand Results

    Energy Technology Data Exchange (ETDEWEB)

    Piette, Mary Ann; Watson, David; Motegi, Naoya; Kiliccote, Sila; Xu, Peng

    2006-04-06

    California utilities have been exploring the use of critical peak prices (CPP) to help reduce needle peaks in customer end-use loads. CPP is a form of price-responsive demand response (DR). Recent experience has shown that customers have limited knowledge of how to operate their facilities in order to reduce their electricity costs under CPP (Quantum 2004). While the lack of knowledge about how to develop and implement DR control strategies is a barrier to participation in DR programs like CPP, another barrier is the lack of automation of DR systems. During 2003 and 2004, the PIER Demand Response Research Center (DRRC) conducted a series of tests of fully automated electric demand response (Auto-DR) at 18 facilities. Overall, the average of the site-specific average coincident demand reductions was 8% from a variety of building types and facilities. Many electricity customers have suggested that automation will help them institutionalize their electric demand savings and improve their overall response and DR repeatability. This report focuses on and discusses the specific results of the Automated Critical Peak Pricing (Auto-CPP, a specific type of Auto-DR) tests that took place during 2005, which build on the automated demand response (Auto-DR) research conducted through PIER and the DRRC in 2003 and 2004. The long-term goal of this project is to understand the technical opportunities of automating demand response and to remove technical and market impediments to large-scale implementation of automated demand response (Auto-DR) in buildings and industry. A second goal of this research is to understand and identify best practices for DR strategies and opportunities. The specific objectives of the Automated Critical Peak Pricing test were as follows: (1) Demonstrate how an automated notification system for critical peak pricing can be used in large commercial facilities for demand response (DR). (2) Evaluate effectiveness of such a system. (3) Determine how customers

  16. Shape Perception and Navigation in Blind Adults.

    Science.gov (United States)

    Gori, Monica; Cappagli, Giulia; Baud-Bovy, Gabriel; Finocchietti, Sara

    2017-01-01

    Different sensory systems interact to generate a representation of space and to navigate. Vision plays a critical role in the representation of space development. During navigation, vision is integrated with auditory and mobility cues. In blind individuals, visual experience is not available and navigation therefore lacks this important sensory signal. In blind individuals, compensatory mechanisms can be adopted to improve spatial and navigation skills. On the other hand, the limitations of these compensatory mechanisms are not completely clear. Both enhanced and impaired reliance on auditory cues in blind individuals have been reported. Here, we develop a new paradigm to test both auditory perception and navigation skills in blind and sighted individuals and to investigate the effect that visual experience has on the ability to reproduce simple and complex paths. During the navigation task, early blind, late blind and sighted individuals were required first to listen to an audio shape and then to recognize and reproduce it by walking. After each audio shape was presented, a static sound was played and the participants were asked to reach it. Movements were recorded with a motion tracking system. Our results show three main impairments specific to early blind individuals. The first is the tendency to compress the shapes reproduced during navigation. The second is the difficulty to recognize complex audio stimuli, and finally, the third is the difficulty in reproducing the desired shape: early blind participants occasionally reported perceiving a square but they actually reproduced a circle during the navigation task. We discuss these results in terms of compromised spatial reference frames due to lack of visual input during the early period of development.

  17. Shape Perception and Navigation in Blind Adults

    Science.gov (United States)

    Gori, Monica; Cappagli, Giulia; Baud-Bovy, Gabriel; Finocchietti, Sara

    2017-01-01

    Different sensory systems interact to generate a representation of space and to navigate. Vision plays a critical role in the representation of space development. During navigation, vision is integrated with auditory and mobility cues. In blind individuals, visual experience is not available and navigation therefore lacks this important sensory signal. In blind individuals, compensatory mechanisms can be adopted to improve spatial and navigation skills. On the other hand, the limitations of these compensatory mechanisms are not completely clear. Both enhanced and impaired reliance on auditory cues in blind individuals have been reported. Here, we develop a new paradigm to test both auditory perception and navigation skills in blind and sighted individuals and to investigate the effect that visual experience has on the ability to reproduce simple and complex paths. During the navigation task, early blind, late blind and sighted individuals were required first to listen to an audio shape and then to recognize and reproduce it by walking. After each audio shape was presented, a static sound was played and the participants were asked to reach it. Movements were recorded with a motion tracking system. Our results show three main impairments specific to early blind individuals. The first is the tendency to compress the shapes reproduced during navigation. The second is the difficulty to recognize complex audio stimuli, and finally, the third is the difficulty in reproducing the desired shape: early blind participants occasionally reported perceiving a square but they actually reproduced a circle during the navigation task. We discuss these results in terms of compromised spatial reference frames due to lack of visual input during the early period of development. PMID:28144226

  18. A Double-Blind Randomized Trial Comparing Implants with Laser-Microtextured and Machined Collar Surfaces: Microbiologic and Clinical Results.

    Science.gov (United States)

    Guarnieri, Renzo; Rappelli, Giorgio; Piemontese, Matteo; Procaccini, Maurizio; Quaranta, Alessandro

    2016-01-01

    The purpose of this study was to compare the clinical outcome of and determine the differences in periodonto-pathogenic microbiota around two types of implant collar surfaces: laser-microtextured (test) vs machined (control). Seventeen patients (11 periodontally healthy, and 6 periodontally compromised) were selected to receive the two different implants, placed randomly, in two edentulous sites. Six months following the surgical placement of the dental implants, subgingival plaque samples were collected using paper points from the peri-implant sulcus and from the sulcus of an adjacent tooth. The presence of five putative periodontal pathogens, namely, Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Prevotella intermedia, Treponema denticola, and Tannerella forsythensis, was assessed using real-time polymerized chain reaction (RT-PCR). Peri-implant parameters and intraoral radiographs were recorded up to 1 year after abutment connection. In the main population, and in the periodontally compromised subgroup, the total number of periodontal pathogens around test implant sites was lower than control implant sites and adjacent tooth sites, with a statistically significant difference (P < .05). In periodontally healthy patients, the mean probing pocket depth for the test implant was 1.31 ± 0.51 mm, compared with 2.66 ± 0.83 mm for the control implant, while in periodontally compromised patients, it was 1.61 ± 0.58 mm for the test implant, compared with a mean value of 2.84 ± 1.0 mm for the control implant. Implants with a laser-microtextured collar surface are not more vulnerable to pathogenic microflora colonization than implants with a machined collar surface. In both of the subgroups of patients (periodontally healthy and periodontally compromised), implants with a laser-microtextured collar surface have a better clinical outcome at 1 year of loading, compared with implants with a machined collar surface.

  19. Influence of test conditions and exposure duration on the result of ecotoxicological tests

    DEFF Research Database (Denmark)

    Rosenkrantz, Rikke Tjørnhøj

    be calculated from results of ecotoxicological tests performed according to internationally approved guidelines, such as from the Organisation for Economic Co-operation and Development (OECD) or International Standardization Organisation (ISO). Such guidelines were originally developed to enable classification...... and hazard ranking of chemicals, and therefore their focus is to measure the toxicity of an artificially maintained continuous exposure under test conditions that rarely reflect natural conditions. This may be in contrast to the aim of establishing EQS, i.e. to protect the natural ecosystem from chemical...... stress. In light of this possible contradiction, the aim of this thesis was to investigate whether EQS derived on the basis of guideline tests will be sufficiently protective of the environment. This was done by exploring the influence of a number of test conditions, such as temperature, light, p...

  20. Algal growth inhibition test results of 425 organic chemical substances

    DEFF Research Database (Denmark)

    Kusk, Kresten Ole; Christensen, Anne Munch; Nyholm, Niels

    2018-01-01

    values were corrected accordingly. The model helped to identify substances, where the calculated water concentration was too uncertain. Substances covering a wide range of physical-chemical properties and different modes of action were tested. Median effect concentrations (EC50) lower than 1000 mg/L were......The toxicity towards the algal species Pseudokirchneriella subcapitata of 425 organic chemical substances was tested in a growth inhibition test. Precautions were taken to prevent loss of the compounds from the water phase and the test system (closed test system, low biomass, shorter test duration......, silanized glass) and to keep pH constant by applying a higher alkalinity. Chemical phase distribution was modelled taking ionization, volatilisation, and adsorption to glass and biomass into consideration. If the modelled water concentration was below 90% of the nominal concentration the calculated EC...

  1. Plasma Volume Expansion Resulting from Intravenous Glucose Tolerance Test

    Directory of Open Access Journals (Sweden)

    Robert G. Hahn

    2011-01-01

    Full Text Available Objective. To quantify the degree of plasma volume expansion that occurs during an intravenous glucose tolerance test (IVGTT. Methods. Twenty healthy volunteers (mean age, 28 years underwent IVGTTs in which 0.3 g/kg of glucose 30% was injected as a bolus over 1 min. Twelve blood samples were collected over 75 min. The plasma glucose and blood hemoglobin concentrations were used to calculate the volume distribution (Vd and the clearance (CL of both the exogenous glucose and the injected fluid volume. Results. The IVGTT caused a virtually instant plasma volume expansion of 10%. The half-life of the glucose averaged 15 min and the plasma volume expansion 16 min. Correction of the fluid kinetic model for osmotic effects after injection reduced CL for the infused volume by 85%, which illustrates the strength of osmosis in allocating fluid back to the intracellular fluid space. Simulations indicated that plasma volume expansion can be reduced to 60% by increasing the injection time from 1 to 5 min and reducing the glucose load from 0.3 to 0.2 g/kg. Conclusion. A regular IVGTT induced an acute plasma volume expansion that peaked at 10% despite the fact that only 50–80 mL of fluid were administered.

  2. Corrugated Quantum Well Infrared Photodetector Focal Plane Array Test Results

    Science.gov (United States)

    Goldberg, A.; Choi, K. K.; Das, N. C.; La, A.; Jhabvala, M.

    1999-01-01

    The corrugated quantum-well infrared photodetector (C-QWIP) uses total internal reflection to couple normal incident light into the optically active quantum wells. The coupling efficiency has been shown to be relatively independent of the pixel size and wavelength thus making the C-QWIP a candidate for detectors over the entire infrared spectrum. The broadband coupling efficiency of the C-QWIP makes it an ideal candidate for multiwavelength detectors. We fabricated and tested C-QWIP focal plane arrays (FPAs) with cutoff wavelengths of 11.2 and 16.2 micrometers. Each FPA has 256 x 256 pixels that are bump-bonded to a direct injection readout circuit. Both FPAs provided infrared imagery with good aesthetic attributes. For the 11.2-micrometers FPA, background-limited performance (BLIP) was observed at 60 K with f/3 optics. For the 16.2-micrometers FPA, BLIP was observed at 38 K. Besides the reduction of dark current in C-QWIP structures, the measured internal quantum efficiency (eta) remains to be high. The values for responsivity and quantum efficiency obtained from the FPA results agree well with those measured for single devices.

  3. Results from the Cold Atom Laboratory's ground test bed

    Science.gov (United States)

    Elliott, Ethan; CAL Team

    2017-04-01

    We describe validation and development of critical technologies in the Cold Atom Laboratory's (CAL) ground test bed, including the demonstration of the first microwave evaporation and generation of dual-species quantum gas mixtures on an atom chip. CAL is a multi-user facility developed by NASA's Jet Propulsion Laboratory (JPL) to provide the first persistent quantum gas platform in the microgravity environment of space. The CAL instrument will be operated aboard the International Space Station (ISS) and utilize a compact atom chip trap loaded from a dual-species magneto optical trap of rubidium and potassium. In the unique environment of microgravity, the confining potentials necessary to the process of cooling atoms can be arbitrarily relaxed, enabling production of gases down to pikoKelvin temperatures and ultra-low densities. Complete removal of the confining potential allows for ultracold clouds that can float virtually fixed relative to the CAL apparatus. This new parameter regime enables ultracold atom research with broad applications in fundamental physics and inertial sensing. Results from the Cold Atom Laboratory's ground testbed.

  4. MTG infrared sounder detection chain: first radiometric test results

    Science.gov (United States)

    Dumestier, D.; Pistone, F.; Dartois, T.; Blazquez, E.

    2017-11-01

    Europe's next fleet of geostationary meteorological satellites, MeteoSat Third Generation, will introduce new functions in addition to continuity of high-resolution meteorological data. The atmosphere Infrared Sounder (IRS), as high -end instrument, is part of this challenging program. IRS principle is a Fourier Transform Interferometer, which allows recomposing atmospheric spectrum after infrared photons detection. Transmission spectrums will be used to support numerical weather prediction. IRS instrument is able to offer full disk coverage in one hour, an on-ground resolution of 4 by 4 km, in two spectral bands (MWIR: 1600 to 2175cm-1 and LWIR: 700 to 1210cm-1) with a spectral resolution of 0.6cm-1. Among critical technologies and processes, IRS detection chain shall offer outstanding characteristics in terms of radiometric performance like Signal to Noise Ratio (SNR), dynamic range and linearity. Selected detectors are HgCdTe two-dimensions arrays, cooled at 55 Kelvins, hybridized on snapshot silicon read-out circuit at 160x160 format. Video electronics present 16 bits resolution, and the whole detection chain (Detectors and electronics) permits to reach SNR between 2 000 and 10 000 as requested by the application. Radiometric onground test results performed on design representative detection chains are presented and are confirming the challenging phase A design choices.

  5. Lloydminster, Saskatchewan vertical well SAGD field test results

    Energy Technology Data Exchange (ETDEWEB)

    Miller, K.A.; Xiao, Y. [Husky Energy Inc., Calgary, AB (Canada)

    2009-07-01

    Vertical and directional wells have been successfully used at Husky Energy's Pikes Peak Steam Project for cyclic steam stimulation (CSS) and follow-up steam drive in the Waseca channel sand reservoir area inside the oil/water contact. As much as 90 per cent recovery was achieved in some areas using combined CSS and follow-up steam drive. A cumulative steam-to-oil ratio (SOR) of less then 3.0 was also achieved. Similar CSS with follow-up drive methods have not been successful outside the oil/water contact. Some improvement in performance was achieved using large CSS slugs and high steam injection rates. However, in many locations CSS performances were still poor, and conversion from CSS to drive has not been successful in any location. Husky initiated a field test of a single vertical well SAGD configuration in 2008 in an area outside the oil/water contact. The objective was to evaluate an alternate process where the conventional CSS performance of 10 wells was very poor from the second or third stimulation onward. The results revealed that a single vertical well SAGD configuration could be successfully completed and operated. However, the oil production rates and the SOR achieved to date have been unsatisfactory.

  6. Tests of composite materials at cryogenic temperatures facilities and results

    CERN Document Server

    Dahlerup-Petersen, K

    1980-01-01

    The design and installation of test facilities for the determination of macromechanical and thermal properties of fiber-reinforced polymer materials at temperatures down to 4.2K are presented. Construction and performance details are given for the following test equipment: quasi- static-tensile and compression-test facilities equipped with an automatic data acquisition system for calculation of material properties, deformation characteristics and various statistics; a thermal contraction-expansion measuring system; a thermal conductivity measurement cell. (1 refs).

  7. Final report on special impact tests of plutonium shipping containers description of test results

    International Nuclear Information System (INIS)

    Bonzon, L.L.

    1977-02-01

    The results from tests conducted to determine the structural response of the LLD-1, Model 1518-6M, and FL-10 plutonium shipping packages when subjected to high-speed impacts (170 to 760 ft/sec) onto unyielding, concrete, and soil targets are presented

  8. Preliminary irradiation test results from the Yankee Atomic Electric Company reactor vessel test irradiation program

    International Nuclear Information System (INIS)

    Biemiller, E.C.; Fyfitch, S.; Campbell, C.A.

    1993-01-01

    The Yankee Atomic Electric Company test irradiation program was implemented to characterize the irradiation response of representative Yankee Rowe reactor vessel beltline plate materials and to remove uncertainties in the analysis of existing irradiation data on the Yankee Rowe reactor vessel steel. Plate materials each containing 0.24 w/o copper, but different nickel contents at 0.63 w/o and 0.19 w/o, were heat treated to simulate the Yankee vessel heat treatment (austenitized at 1800 deg F) and to simulate Regulatory Guide 1.99 database materials (austenitized at 1600 deg. F). These heat treatments produced different microstructures so the effect of microstructure on irradiation damage sensitivity could be tested. Because the nickel content of the test plates varied and the copper level was constant, the effect of nickel on irradiation embrittlement was also tested. Correlation monitor material, HSST-02, was included in the program to benchmark the Ford Nuclear Reactor (U. of Michigan Test Reactor) which had never been used for this type of irradiation program. Materials taken from plate surface locations (vs. 1/4T) were included to test whether or not the improved toughness properties of the plate surface layer, resulting from the rapid quench, is maintained after irradiation. If the improved properties are maintained, pressurized thermal shock calculations could utilize this margin. Finally, for one experiment, irradiations were conducted at two irradiation temperatures (500 deg. F and 550 deg. F) to determine the effect of irradiation temperature on embrittlement. The preliminary results of the irradiation program show an increase in T 30 shift of 69 deg. F for a decrease in irradiation temperature of 50 deg. F. The results suggest that for nickel bearing steels, the superior toughness of plate surface material is maintained after irradiation and for the copper content tested, nickel had no apparent effect on irradiation response. No apparent microstructure

  9. Li-Ion Cell Lot Testing and Flight Screening Results

    Science.gov (United States)

    2011-02-01

    This document reports the lot characterization and sample testing required for certification of a new lot of Moli-Energy Li-lon ICR-18650H 2200-mAh...cells that constitute this new lot are also presented. All testing began upon receipt of the new cell lot in March 2(K)9 and was performed with the

  10. Cone Penetrometer Load Cell Temperature and Radiation Testing Results

    Energy Technology Data Exchange (ETDEWEB)

    Follett, Jordan R.

    2013-08-28

    This report summarizes testing activities performed at the Pacific Northwest National Laboratory to verify the cone penetrometer load cell can withstand the tank conditions present in 241-AN-101 and 241-AN-106. The tests demonstrated the load cell device will operate under the elevated temperature and radiation levels expected to be encountered during tank farm deployment of the device.

  11. HIPPARCOS satellite: Aeritalia involvement and system test activities and results

    Science.gov (United States)

    Strim, B.; Cugno, W.; Morsillo, G.

    when observed from two different points, for example, from two different points in the Earth's orbit around the sun. Distance can be calculated using parallax measurements). The satellite payload is a Schmidt reflecting telescope with two openings 58 degrees apart. The design allows stars in two different parts of the sky to be observed at the same time. Internally, the two fields of view are combined and the angular separation between pairs of stars - one star from each field of view - is recorded. Over the 2.5-year life of the HIPPARCOS mission, millions of such measurements between star pairs as faint as magnitude 13 will be made covering the entire celestial sphere. The data will be compiled into the HIPPARCOS catalog. The accuracy of these measurements for most of the stars is expected to be within 0.002 arcsec, an improvement of about a factor of 20 over ground-based observations. A second experiment, called TYCHO, will collect position and photometric data on about 400.000 stars. Although less accurate than the main experiment, TYCHO will provide astronomers with a reference catalog for a large number of stars. Both the HIPPARCOS and TYCHO star catalogs are expected to be available to the worldwide astronomical community by around 1994. The launch weight of HIPPORCOS is 1.140 kg. It will be put into geostationary orbit by an Ariane rocket. Purpose of the present paper is to put the spotlight on the system tests performed on the Satellite Structural Thermal Model STM, the Engineering Model EM and to summarize the main results so far obtained. A description of the System and Spacecraft design to better understand the mission and system requirements is also presented.

  12. High Temperature Ultrasonic Probe and Pulse-Echo Probe Mounting Fixture for Testing and Blind Alignment on Steam Pipes

    Science.gov (United States)

    Bar-Cohen, Yoseph (Inventor); Badescu, Mircea (Inventor); Lih, Shyh-Shiuh (Inventor); Sherrit, Stewart (Inventor); Takano, Nobuyuki (Inventor); Ostlund, Patrick N. (Inventor); Lee, Hyeong Jae (Inventor); Bao, Xiaoqi (Inventor)

    2017-01-01

    A high temperature ultrasonic probe and a mounting fixture for attaching and aligning the probe to a steam pipe using blind alignment. The high temperature ultrasonic probe includes a piezoelectric transducer having a high temperature. The probe provides both transmitting and receiving functionality. The mounting fixture allows the high temperature ultrasonic probe to be accurately aligned to the bottom external surface of the steam pipe so that the presence of liquid water in the steam pipe can be monitored. The mounting fixture with a mounted high temperature ultrasonic probe are used to conduct health monitoring of steam pipes and to track the height of condensed water through the wall in real-time.

  13. Results of thermal test of metallic molybdenum disk target and fast-acting valve testing

    Energy Technology Data Exchange (ETDEWEB)

    Virgo, M. [Argonne National Lab. (ANL), Argonne, IL (United States); Chemerisov, S. [Argonne National Lab. (ANL), Argonne, IL (United States); Gromov, R. [Argonne National Lab. (ANL), Argonne, IL (United States); Jonah, C. [Argonne National Lab. (ANL), Argonne, IL (United States); Vandegrift, G. F. [Argonne National Lab. (ANL), Argonne, IL (United States)

    2016-12-01

    This report describes the irradiation conditions for thermal testing of helium-cooled metallic disk targets that was conducted on March 9, 2016, at the Argonne National Laboratory electron linac. The four disks in this irradiation were pressed and sintered by Oak Ridge National Laboratory from molybdenum metal powder. Two of those disks were instrumented with thermocouples. Also reported are results of testing a fast-acting-valve system, which was designed to protect the accelerator in case of a target-window failure.

  14. Thermal-Chemical Model Of Subduction: Results And Tests

    Science.gov (United States)

    Gorczyk, W.; Gerya, T. V.; Connolly, J. A.; Yuen, D. A.; Rudolph, M.

    2005-12-01

    Seismic structures with strong positive and negative velocity anomalies in the mantle wedge above subduction zones have been interpreted as thermally and/or chemically induced phenomena. We have developed a thermal-chemical model of subduction, which constrains the dynamics of seismic velocity structure beneath volcanic arcs. Our simulations have been calculated over a finite-difference grid with (201×101) to (201×401) regularly spaced Eulerian points, using 0.5 million to 10 billion markers. The model couples numerical thermo-mechanical solution with Gibbs energy minimization to investigate the dynamic behavior of partially molten upwellings from slabs (cold plumes) and structures associated with their development. The model demonstrates two chemically distinct types of plumes (mixed and unmixed), and various rigid body rotation phenomena in the wedge (subduction wheel, fore-arc spin, wedge pin-ball). These thermal-chemical features strongly perturb seismic structure. Their occurrence is dependent on the age of subducting slab and the rate of subduction.The model has been validated through a series of test cases and its results are consistent with a variety of geological and geophysical data. In contrast to models that attribute a purely thermal origin for mantle wedge seismic anomalies, the thermal-chemical model is able to simulate the strong variations of seismic velocity existing beneath volcanic arcs which are associated with development of cold plumes. In particular, molten regions that form beneath volcanic arcs as a consequence of vigorous cold wet plumes are manifest by > 20% variations in the local Poisson ratio, as compared to variations of ~ 2% expected as a consequence of temperature variation within the mantle wedge.

  15. Test results and commercialization plans for long life Stirling generators

    International Nuclear Information System (INIS)

    Erbeznik, R.M.; White, M.A.

    1996-01-01

    Many optimistic predictions regarding commercialization of Stirling engines have been announced over the years, but to date no real successes have emerged. STC is excited to announce the availability of beta prototypes for its RemoteGen trademark family of free-piston Stirling generators. STC is working with suppliers, manufacturers, and beta customers to commercialize the RemoteGen family of generators. STC is proving that these machines overcome previously inhibiting barriers by providing long life, high reliability, cost effective mass production, and market relevance. Stirling power generators are generally acknowledged to offer much higher conversion efficiencies than direct energy conversion systems. Life and reliability, on the other hand, are generally considered superior for direct conversion systems, as established by the exceptional endurance records (though with degradation) for thermoelectric (TE) and photovoltaic (PV) systems. STC's unique approaches combine dynamic system efficiency with static system reliability. The RemoteGen family presently includes a 10-watt RG-10, a 350-watt RG-350, and with 1-kW and 3-kW sizes planned for the future. They all use the same basic configuration with flexure bearings, clearance seals, and moving iron linear alternators. The third generation RG-10 has entered limited production with a radioisotope-fueled version, and a niche market for a propane-fueled version has been identified. Market analysis has led STC to focus on early commercial production of the RG-350. The linear alternator power module portion of the RG-350 is also used in its sister BeCool trademark family of coolers as the linear motor. By using a common power module, both programs will benefit by each other's commercialization efforts. The technology behind the RemoteGen generators, test results, and plans for commercialization are described in this paper

  16. The IEA large coil task test results in IFSMTF

    International Nuclear Information System (INIS)

    Lubell, M.S.; Clinard, J.A.; Dresner, L.

    1987-01-01

    The Large Coil Task (LCT) is an international collaboration of the United States, EURATOM, Japan, and Switzerland to develop large superconducting magnets for fusion reactors. The testing phase of LCT was completed on September 3, 1987. All six coils exceeded the design goals, both as single coils and in six-coil toroidal tests. In addition, a symmetric torus test was performed in which a maximum field of 9 T was reached in all coils simultaneously. These are by far the largest magnets (either in size, weight, or stored energy) ever to achieve such a field. 6 refs., 6 figs., 3 tabs

  17. Battery cycling and calendar aging: year one testing results.

    Science.gov (United States)

    2016-07-01

    This report is meant to provide an update on the ongoing battery testing performed by the Hawaii Natural Energy Institute to evaluate Electric Vehicle (EV) battery durability and reliability under electric utility grid operations. Commercial EV batte...

  18. CHALLENGE TESTS WITH LISTERIA MONOCYTOGENES IN SALAMI: PRELIMINARY RESULTS

    Directory of Open Access Journals (Sweden)

    R. Mioni

    2013-02-01

    Full Text Available Challenge tests are the preferable methodology to study the behaviour of Listeria monocytogenes on ready to eat foods, according to Regulation (EC 2073/2005. Challenge testing using L. monocytogenes in seasoned salami from different food business operators showed, after seasoning of the product, a count reduction of the inoculated organisms without any further growth of the pathogen; however differences of L. monocytogenes behaviour could be observed according to different production protocols.

  19. SLAC FASTBUS Snoop Module: test results and support software

    International Nuclear Information System (INIS)

    Gustavson, D.B.; Walz, H.V.

    1985-09-01

    The development of a diagnostic module for FASTBUS has been completed. The Snoop Module is designed to reside on a Crate Segment and provide high-speed diagnostic monitoring and testing capabilities. Final hardware details and testing of production prototype modules are reported. Features of software under development for a stand-alone single Snoop diagnostic system and Multi-Snoop networks will be discussed. 3 refs., 2 figs

  20. SIMS prototype system 1 test results: Engineering analysis

    Science.gov (United States)

    1978-01-01

    The space and domestic water solar heating system designated SIMS Prototype Systems 1 was evaluated. The test system used 720 ft (gross) of Solar Energy Products Air Collectors, a Solar Control Corporation SAM 20 Air Handler with Model 75-175 control unit, a Jackson Solar Storage tank with Rho Sigma Mod 106 controller, and 20 tons of rack storage. The test data analysis performed evaluates the system performance and documents the suitability of SIMS Prototype System 1 hardware for field installation.

  1. Change blindness and eyewitness testimony.

    Science.gov (United States)

    Davies, Graham; Hine, Sarah

    2007-07-01

    The authors explored the relevance of research on change blindness to eyewitness identification and testimony under intentional and incidental memory conditions. Participants (N = 80, 40 men and 40 women) viewed a video enactment of a burglary in which the identity of the burglar changed at the halfway point of the film. Half of participants were briefed to remember the content, and the other half were not. All were tested for the recall of the content, awareness of the change, and ability to identify either or both of the burglars. Some 61% of participants did not notice the identity change. Rates of detection were significantly higher in participants in the intentional condition, who also recalled significantly more detail from the film. Awareness of change was also significantly related to content recall scores and accuracy of identification of both burglars. The results illustrate the interrelation between the eyewitness and change blindness literatures.

  2. One-year results of a prospective randomized, evaluator-blinded, multicenter study comparing TVT and TVT Secur.

    OpenAIRE

    Andrada Hamer, Maria; Larsson, Per-Göran; Teleman, Pia; Bergqvist, Christina Eten; Persson, Jan

    2012-01-01

    INTRODUCTION AND HYPOTHESIS: The aim of this prospective randomized multicenter study was to compare retropubic tension-free vaginal tape (TVT) with TVT Secur in terms of efficacy and safety. METHODS: We set out to enrol 280 stress urinary incontinent (SUI) women with a half-time interim analysis of short-term cure and adverse events. The short-term results have previously been published. Of the133 randomized women, 125 underwent surgery, and 121 (TVT n = 61, TVT Secur n = 60)...

  3. Results of a phase II double-blinded randomized clinical trial of difluoromethylornithine for cervical intraepithelial neoplasia grades 2 to 3.

    Science.gov (United States)

    Vlastos, Anne-Thérèse; West, Loyd A; Atkinson, E Neely; Boiko, Iouri; Malpica, Anais; Hong, Waun K; Follen, Michele

    2005-01-01

    Our purpose was to conduct a double-blinded randomized trial of difluoromethylornithine (DFMO) at 0.125, 0.5 gm/m2, versus placebo in the treatment of cervical intraepithelial neoplasia (CIN) grades 2 to 3. A promising phase I study has shown histopathologic responses at these dose levels. Patients with histopathologically confirmed CIN 2-3 lesions were recruited from a colposcopy clinic and underwent Papanicolaou testing, human papillomavirus testing, and colpophotography. They took oral contraception and DFMO or placebo elixir for 28 days and filled out the National Cancer Institute common toxicity calendars. They returned for follow-up and a repeat Papanicolaou smear, colpophotograph, and loop excision of the cervix. There were no statistically significant differences among the arms in histopathologic response. This could no be explained by any biases in risk factors. The prominent toxicities were diarrhea, dizziness, nausea, and headaches. There were no differences in the toxicities among arms. The Papanicolaou smear was a poor biomarker of response and correlated poorly with the histopathology. DFMO is no active at 0.125 and 0.5 gm/m2 for 28 days when given orally in CIN 2-3. Higher oral doses or longer administration is necessary, supporting data from breast trials. Alternatively, a trial of topical DFMO might merit attention as activity has been noted in trials of actinic keratoses.

  4. Post-test investigation result on the WWER-1000 fuel tested under severe accident conditions

    International Nuclear Information System (INIS)

    Goryachev, A.; Shtuckert, Yu.; Zwir, E.; Stupina, L.

    1996-01-01

    The model bundle of WWER-type were tested under SFD condition in the out-of-pile CORA installation. The objective of the test was to provide an information on the WWER-type fuel bundles behaviour under severe fuel damage accident conditions. Also it was assumed to compare the WWER-type bundle damage mechanisms with these experienced in the PWR-type bundle tests with aim to confirm a possibility to use the various code systems, worked our for PWR as applied to WWER. In order to ensure the possibility of the comparison of the calculated core degradation parameters with the real state of the tested bundle, some parameters have been measured on the bundle cross-sections under examination. Quantitative parameters of the bundle degradation have been evaluated by digital image processing of the bundle cross-sections. The obtained results are shown together with corresponding results obtained by the other participants of this investigation. (author). 3 refs, 13 figs

  5. Hunter standoff killer team (HSKT) ground and flight test results

    Science.gov (United States)

    Moreland, Balinda; Ennis, Mark; Yeates, Robert; Condon, Timothy

    2007-04-01

    Warfighter's Associate (WA) which was integrated onto the Apache Longbow, and the Mobile Commanders Associate (MCA) which was integrated onto the Army Airborne Command and Control System (A2C2S) UH-60 Blackhawk. In this paper we will discuss what WA and MCA provided to the warfighter, and the results of the HSKT ground and flight testing.

  6. Results from Carbon Dioxide Washout Testing Using a Suited Manikin Test Apparatus with a Space Suit Ventilation Test Loop

    Science.gov (United States)

    Chullen, Cinda; Conger, Bruce; McMillin, Summer; Vonau, Walt; Kanne, Bryan; Korona, Adam; Swickrath, Mike

    2016-01-01

    NASA is developing an advanced portable life support system (PLSS) to meet the needs of a new NASA advanced space suit. The PLSS is one of the most critical aspects of the space suit providing the necessary oxygen, ventilation, and thermal protection for an astronaut performing a spacewalk. The ventilation subsystem in the PLSS must provide sufficient carbon dioxide (CO2) removal and ensure that the CO2 is washed away from the oronasal region of the astronaut. CO2 washout is a term used to describe the mechanism by which CO2 levels are controlled within the helmet to limit the concentration of CO2 inhaled by the astronaut. Accumulation of CO2 in the helmet or throughout the ventilation loop could cause the suited astronaut to experience hypercapnia (excessive carbon dioxide in the blood). A suited manikin test apparatus (SMTA) integrated with a space suit ventilation test loop was designed, developed, and assembled at NASA in order to experimentally validate adequate CO2 removal throughout the PLSS ventilation subsystem and to quantify CO2 washout performance under various conditions. The test results from this integrated system will be used to validate analytical models and augment human testing. This paper presents the system integration of the PLSS ventilation test loop with the SMTA including the newly developed regenerative Rapid Cycle Amine component used for CO2 removal and tidal breathing capability to emulate the human. The testing and analytical results of the integrated system are presented along with future work.

  7. Using GPS to determine vehicle attitude - USS Yorktown test results

    Science.gov (United States)

    Kruczynski, Leonard R.; Li, Pui C.; Evans, Alan G.; Hermann, Bruce R.

    Prototype GPS orientation equipment was tested aboard the USS Yorktown, a U.S. Navy guided missile cruiser, to demonstrate that GPS could be used to determine orientation on a moving vessel. Initialization, integer maintenance, and accuracy in a real-time dynamic environment were addressed. The tests confirmed GPS-based real-time orientation determination, provided real-world data to exercise enhanced orientation algorithms, and identified equipment improvements that will make GPS a viable source of vehicle attitude in addition to GPS's superior positioning capabilities.

  8. Performance of CREAM Calorimeter Results of Beam Tests

    CERN Document Server

    Ahn, H S; Beatty, J J; Bigongiari, G; Castellina, A; Childers, J T; Conklin, N B; Coutu, S; Duvernois, M A; Ganel, O; Han, J H; Hyun, H J; Kang, T G; Kim, H J; Kim, K C; Kim, M Y; Kim, T; Kim, Y J; Lee, J K; Lee, M H; Lutz, L; Maestro, P; Malinine, A; Marrocchesi, P S; Mognet, S I; Nam, S W; Nutter, S; Park, N H; Park, H; Seo, E S; Sina, R; Syed, S; Song, C; Swordy, S; Wu, J; Yang, J; Zhang, H Q; Zei, R; Zinn, S Y

    2005-01-01

    The Cosmic Ray Energetics And Mass (CREAM), a balloon-borne experiment, is under preparation for a flight in Antarctica at the end of 2004. CREAM is planned to measure the energy spectrum and composition of cosmic rays directly at energies between 1 TeV and 1000 TeV. Incident particle energies will be measured by a transition radiation detector and a sampling calorimeter. The calorimeter was constructed at the University of Maryland and tested at CERN in 2003. Performance of the calorimeter during the beam tests is reported.

  9. Superior Orthonasal but Not Retronasal Olfactory Skills in Congenital Blindness

    DEFF Research Database (Denmark)

    Gagnon, Lea; Ismaili, Abd Rahman Alaoui; Ptito, Maurice

    2015-01-01

    olfactory but reduced taste perception. In this study we tested the hypothesis that congenitally blind subjects have enhanced orthonasal but not retronasal olfactory skills. Twelve congenitally blind and 14 sighted control subjects, matched in age, gender and body mass index, were asked to identify odours...... using grocery-available food powders. Results showed that blind subjects were significantly faster and tended to be better at identifying odours presented orthonasally. This was not the case when odorants were presented retronasally. We also found a significant group x route interaction, showing...... that although both groups performed better for retronasally compared to orthonasally presented odours, this gain was less pronounced for blind subjects. Finally, our data revealed that blind subjects were more familiar with the orthonasal odorants and used the retronasal odorants less often for cooking than...

  10. Preliminary irradiation test results from the Yankee Atomic Electric Company reactor vessel test irradiation program

    International Nuclear Information System (INIS)

    Biemiller, E.C.; Fyfitch, Stephen; Campbell, C.A.

    1994-01-01

    The Yankee Atomic Electric Company test irradiation program was implemented to characterize the irradiation response of representative Yankee Rowe reactor vessel beltline plate materials and to remove uncertainties in the analysis of existing irradiation data on the Yankee Rowe reactor vessel steel. Plate materials each containing 0.24 w/o copper, but different nickel contents at 0.63 w/o and 0.19 w/o, were heat treated to simulate the Yankee vessel heat treatment (austenitized at 982 o C (1800 o F)) and to simulate Regulatory Guide 1.99 database materials (austenitized at 871 o C (1600 o F)). These heat treatments produced different microstructures so the effect of microstructure on irradiation damage sensitivity could be tested. Because the nickel content of the test plates varied and the copper level was constant, the effect of nickel on irradiation embrittlement was also tested. Correlation monitor material, HSST-02, was included in the program to benchmark the Ford Nuclear Reactor (University of Michigan Test Reactor) which had never been used before for this type of irradiation program. Materials taken from plate surface locations (versus 1/4 T) were included to test whether or not the improved toughness properties of the plate surface layer, resulting from the rapid quench, are maintained after irradiation. If the improved properties are maintained, pressurized thermal shock calculations could utilize this margin. Finally, for one experiment, irradiations were conducted at two irradiation temperatures (260 o C and 288 o C) to determine the effect of irradiation temperature on embrittlement. (Author)

  11. Designs and test results for three new rotational sensors

    Czech Academy of Sciences Publication Activity Database

    Jedlička, Petr; Kozák, Jan; Evans, J. R.; Hutt, C. R.

    2012-01-01

    Roč. 16, č. 4 (2012), s. 639-647 ISSN 1383-4649 R&D Projects: GA MŠk(CZ) ME10008 Institutional research plan: CEZ:AV0Z30120515 Keywords : rotational seismology * seismometry * instrument testing * instrument design Subject RIV: DC - Siesmology, Volcanology, Earth Structure Impact factor: 1.388, year: 2012

  12. The Mark III vertex chamber and prototype test results

    International Nuclear Information System (INIS)

    Grab, C.

    1987-07-01

    A vertex chamber has been constructed for use in the Mark III experiment. The chamber is positioned inside the current main drift chamber and will be used to trigger data collection, to aid in vertex reconstruction, and to improve the momentum resolution. This paper discusses the chamber's construction and performance and tests of the prototype

  13. Acquired intolerance to organic solvents and results of vestibular testing

    Energy Technology Data Exchange (ETDEWEB)

    Gyntelberg, F.; Vesterhauge, S.; Fog, P.; Isager, H.; Zillstorff, K.

    1986-01-01

    Among 160 consecutive patients referred to the Clinic of Occupational Medicine, Rigshospitalet, for symptoms connected with exposure to organic solvents, 20 exhibited symptoms of acquired intolerance to minor amounts of organic solvents. Later, an additional 30 consecutive patients with symptoms of acquired intolerance were included, yielding a total of 43 men and 7 women. The characteristics of the clinical syndrome described are complaints of dizziness, nausea, and weakness after exposure to minimal solvent vapor concentrations. After having tolerated long-term occupational exposure to moderate or high air concentrations of various organic solvents, the patients became intolerant within a short period of time. Since dizziness was a frequent complaint, we tried to obtain a measure of the patients' complaints using vestibular tests. As a diagnostic test the combined vestibular tests had a sensitivity of 0.55 and a specificity of 0.87. No differences between patients with and without intolerance could be detected by the vestibular tests used. We conclude that acquired intolerance to organic solvents is a new but characteristic and easily recognizable syndrome, often with severe consequences for the patient's working ability.

  14. Aggregating Polytomous DIF Results over Multiple Test Administrations

    Science.gov (United States)

    Zwick, Rebecca; Ye, Lei; Isham, Steven

    2018-01-01

    In typical differential item functioning (DIF) assessments, an item's DIF status is not influenced by its status in previous test administrations. An item that has shown DIF at multiple administrations may be treated the same way as an item that has shown DIF in only the most recent administration. Therefore, much useful information about the…

  15. Results of Laboratory Testing of Advanced Power Strips

    Energy Technology Data Exchange (ETDEWEB)

    Earle, L. [National Renewable Energy Lab. (NREL), Golden, CO (United States); Sparn, B. [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2012-08-01

    Presented at the ACEEE Summer Study on Energy Efficiency in Buildings on August 12-17, 2012, this presentation reports on laboratory tests of 20 currently available advanced power strip products, which reduce wasteful electricity use of miscellaneous electric loads in buildings.

  16. TEST RESULTS FOR FUEL CELL OPERATION ON ANAEROBIC DIGESTER GAS

    Science.gov (United States)

    EPA, in conjunction with ONSI Corp., embarked on a project to define, design, test, and assess a fuel cell energy recovery system for application at anaerobic digester waste water (sewage) treatment plants. Anaerobic digester gas (ADG) is produced at these plants during the proce...

  17. Results of Caisson Breakwater Tests in Multidirectional Breaking Seas

    DEFF Research Database (Denmark)

    Kofoed, Jens Peter

    In extension of the work done at the Hydraulics and Coastal Engineering Laboratory, Dept. of Civil Engineering, Aalborg University, Denmark, described in Grønbech et al., 1997, laboratory tests has been performed investigating wave loading and overtopping on caisson breakwaters in multidirectional...

  18. Preliminary test results for analogy experiment methodology developments

    International Nuclear Information System (INIS)

    Ko, Sang Hyuk; Chung, Bum Jin

    2005-01-01

    Expanded use of hydrogen as an energy carrier could help address concerns about global climate change and energy security. Hydrogen can be derived from a variety of domestically available primary sources such as fossil fuels, renewables, and nuclear power. The idea of hydrogen production by using the heat from nuclear power, HTGR (High-Temperature Gas-cooled Reactor), seems to be promising. The knowledge of detailed heat transfer phenomena in gaseous phase emerges as an important factor for HTGR, where buoyancy force plays a significant role. Large and expensive test facilities are to be constructed to assess the detailed mixed convection phenomena. However, using the analogy concept, a simple and cheap test facility could replace those. This study explores the feasibility of the idea

  19. Results of experiments in the THIBO II test section

    International Nuclear Information System (INIS)

    Bojarsky, E.; Deckers, H.; Lehning, H.; Piel, D.; Reiser, H.; Schmidt, L.

    1989-10-01

    It was possible to prove in 1988 in the course of the THIBO I experiments; that under certain operating conditions thermohydraulically induced rod damaging oscillations may occur in sodium cooled Mark II fuel elements. Since May 1989 another THIBO II test series has been performed in a new test section of the sodium loop of the IMF III. The area of the coolant channel was reduced to approximately half its previous surface so that the thermohydraulic conditions come very close to those prevailing in the KNK II reactor. The experiments have shown that even with minor sodium enthalpy raises and low rating, respectively, motions of the fuel pins can be induced. This applies also in cases where the clearance of the pin in the spacer has been set to realistically low values

  20. Results from the average power laser experiment photocathode injector test

    International Nuclear Information System (INIS)

    Dowell, D.H.; Bethel, S.Z.; Friddell, K.D.

    1995-01-01

    Tests of the electron beam injector for the Boeing/Los Alamos Average Power Laser Experiment (APLE) have demonstrated first time operation of a photocathode RF gun accelerator at 25% duty factor. This exceeds previous photocathode operation by three orders of magnitude. The success of these tests was dependent upon the development of reliable and efficient photocathode preparation and processing. This paper describes the fabrication details for photocathodes with quantum efficiencies up to 12% which were used during electron beam operation. Measurements of photocathode lifetime as it depends upon the presence of water vapor are also presented. Observations of photocathode quantum efficiency rejuvenation and extended lifetime in the RF cavities are described. The importance of these effects upon photocathode lifetime during high average power operation are discussed. ((orig.))

  1. Test beam results of LHCb scintillating fibre tracker prototypes

    Energy Technology Data Exchange (ETDEWEB)

    Bachmann, Sebastian; Comerma, Albert; Gerick, David; Hansmann-Menzemer, Stephanie; Kecke, Matthieu; Leverington, Blake; Mazorra de Cos, Jose; Mitzel, Dominik; Neuner, Max; Uwer, Ulrich; Han, Xiaoxue [Physikalisches Institut, Universitaet Heidelberg (Germany); Collaboration: LHCb-Collaboration

    2016-07-01

    During the Long Shutdown 2 of the LHC, the LHCb detector will undergo a major upgrade to meet the challenges of running at a higher luminosity. The current Inner and Outer Tracking system will not be sufficient to deal with the envisaged increased detector occupancy and higher radiation levels and will be replaced by a single tracking detector based on 0.250 mm diameter plastic scintillating fibres. The fibres are wound to multilayer ribbons 2.4 m long and read out by 128 channel silicon photomultiplier arrays. The Scintillating Fibre (SciFi) tracker will cover a total active area of 360 m{sup 2}, arranged in 12 layers. The performances of prototype modules having 6 and 8 layers of fibre have been tested at the SPS at CERN. This talk focuses on basic properties of the prototype modules such as spatial resolution, single hit efficiency and light yield measured during the test beam campaigns in 2015.

  2. Sublimator Driven Coldplate Engineering Development Unit Test Results

    Science.gov (United States)

    Sheth, Rubik B.; Stephan, Ryan A.; Leimkuehler, Thomas O.

    2010-01-01

    The Sublimator Driven Coldplate (SDC) is a unique piece of thermal control hardware that has several advantages over a traditional thermal control scheme. The principal advantage is the possible elimination of a pumped fluid loop, potentially increasing reliability and reducing complexity while saving both mass and power. Because the SDC requires a consumable feedwater, it can only be used for short mission durations. Additionally, the SDC is ideal for a vehicle with small transport distances and low heat rejection requirements. An SDC Engineering Development Unit was designed and fabricated. Performance tests were performed in a vacuum chamber to quantify and assess the performance of the SDC. The test data was then used to develop correlated thermal math models. Nonetheless, an Integrated Sublimator Driven Coldplate (ISDC) concept is being developed. The ISDC couples a coolant loop with the previously described SDC hardware. This combination allows the SDC to be used as a traditional coldplate during long mission phases and provides for dissimilar system redundancy

  3. The Aluminum Ship Evaluation Model (ASEM) Static Test Results

    Science.gov (United States)

    1983-12-01

    At each load frame, one starboard hydraulic acuator or jack and one or two keel jacks (coupled with closed-loop, feedback system load cells) were used...zero, system lock and unlock, and lateral offset. Each test was performed enough times to establish repeatable linear strain response with load. A...to obtain the strain readings. The linearity in load versus strain response and, thus, the basic stress sensitivities (numbers of pounds per square

  4. 1-g model loading tests: methods and results

    Czech Academy of Sciences Publication Activity Database

    Feda, Jaroslav

    1999-01-01

    Roč. 2, č. 4 (1999), s. 371-381 ISSN 1436-6517. [Int.Conf. on Soil - Structure Interaction in Urban Civ. Engineering. Darmstadt, 08.10.1999-09.10.1999] R&D Projects: GA MŠk OC C7.10 Keywords : shallow foundation * model tests * sandy subsoil * bearing capacity * subsoil failure * volume deformation Subject RIV: JM - Building Engineering

  5. Test result of on-line coal ash content meter

    Energy Technology Data Exchange (ETDEWEB)

    Onodera, Jiro

    1988-10-25

    A two-line permeation type coal ash content meter was tested in on-line measurement. The used coal ash content meter irradiates gamma rays from A/sub m/ and C/sub s/, radioactive isotopes, to coal layer on the belt conveyer, continuously detects each of those gamma rays in permeation intensity by the scintillation counter, and digitally indicates the ash content indication value through the signal processing. At the coal quarrying stage by the low ash content coal preparation belt conveyer, test sample was collected at all times, and the relation of its ash content with the gamma ray intensity was investigated. In ash content range of 15 to 35%, an assumed error of 1.3% was obtained. The standardized intensity of gamma rays, as varying due to the thickness of belt, ambient temperature of detector and other factors, must be periodically tested in accuracy. Against sample, large in variance in water and vapor content, the adjustment by the water content meter is required. Further in case of the variance in H atom in coal, and Ca and Fe atoms in ash, as the mass damping coefficient varies against the Am gamma rays, it is advisable to apply, to each individual brend, the ash content calculation purpose regression formula. 8 references, 5 figures, 1 table.

  6. Treatment of cyclical mastalgia with a solution containing a Vitex agnus castus extract: results of a placebo-controlled double-blind study.

    Science.gov (United States)

    Halaska, M; Beles, P; Gorkow, C; Sieder, C

    1999-08-01

    In a placebo-controlled, randomized, double-blind study the efficacy of a Vitex agnus castus extract-containing solution (VACS) was investigated in patients suffering from cyclical mastalgia. Patients had mastalgia on at least 5 days in the pre-treatment cycle. During this cycle and during treatment (3 cycles; 2 x 30 drops/day), the intensity of mastalgia was recorded once per cycle using a visual analogue scale (VAS). After one/two treatment cycles, the mean decrease in pain intensity (mm, VAS) was 21.4 mm /33.7 mm in women taking VACS (n=48) and 10.6 mm/20.3 mm with placebo (n=49). The differences of the VAS-values for VACS were significantly greater than those with placebo (p=0.018; p=0.006). After three cycles, the mean VAS-score reduction for women taking VACS was 34.3 mm, a reduction of 'borderline significance' (p=0.064) on statistical testing compared with placebo (25.7 mm). There was no difference in the frequency of adverse events between both groups (VACS: n=5; placebo : n=4). VACS appears effective and was well tolerated and further evaluation of this agent in the treatment of cyclical mastalgia is warranted.

  7. [Investigation of the effect of oxymetazoline on the duration of rhinitis. results of a placebo-controlled double-blind study in patients with acute rhinitis].

    Science.gov (United States)

    Reinecke, S; Tschaikin, M

    2005-10-06

    A prospective placebo-controlled double-blind study investigated the question whether oxymetazoline has a clinically relevant impact on the duration of acute rhinitis. The study included 247 patients with acute rhinitis who, over a maximum of 10 days, received either oxymetazoline hydrochloride (test substance group) or physiological saline solution applied in the form of a spray (control group). The main target measure was the duration of rhinitis, with time to onset of effect and symptoms as secondary measures. The safety of the treatment was determined on the basis of patient satisfaction, heart rate measurement, and undesired side effects recorded. The duration of the rhinitis decreased significantly under oxymetazoline in comparison with the control group (4 vs. 6 days). On average, the effect of oxymetazoline set in after 25 seconds, as compared with 90 seconds for physiological saline (difference significant, P oxymetazoline group, and were identical again in both arms of the study from the 9th day onward. The physicians assessed the efficacy of oxymetazoline to be good orvery good in 85% of the cases as compared with 38% for the physiological saline solution (P oxymetazoline group assessed the effect to be good or very good, as compared with 44% in the patients in the physiological saline group (P oxymetazoline to be significantly superior to physiological saline solution. Treatment with the former significantly shortened the duration of the rhinitis by one-third (2 days).

  8. Biochemical markers of bone turnover associated with calcium supplementation in children with juvenile rheumatoid arthritis: results of a double-blind, placebo-controlled intervention trial.

    Science.gov (United States)

    Carrasco, Ruy; Lovell, Daniel J; Giannini, Edward H; Henderson, Carol J; Huang, Bin; Kramer, Sandy; Ranz, Julie; Heubi, James; Glass, David

    2008-12-01

    To determine the effects of calcium supplementation on bone physiology in corticosteroid-free children with juvenile rheumatoid arthritis (JRA) by measuring serum and urinary bone-related hormones, minerals, and markers of bone formation and resorption. In this double-blind trial, patients were randomized to receive daily oral supplementation with 1,000 mg of calcium and 400 IU of vitamin D or with placebo and 400 IU of vitamin D for 24 months. The effect of calcium supplementation on bone physiology was determined periodically using markers of bone turnover. One hundred ninety-eight patients met the inclusion criteria and were followed up in the study. At baseline, there were no differences in markers of bone turnover between the groups. Patients with urine phosphorus were lower in the group receiving calcium supplementation. Hypercalciuria, as determined by the urinary calcium-to-creatinine ratio, was not noted in 24-hour urine studies. Levels of markers of bone physiology were significantly decreased in children with JRA receiving calcium supplementation. The physiologic changes were noted as early as 12 months into calcium supplementation. The hypercalciuria noted on spot testing of the urinary calcium-to-creatinine ratio was not demonstrated on further evaluation, nor did it lead to renal pathology. These findings suggest that the calcium supplementation met physiologic needs and caused an increased calcium loss in urine.

  9. Efficacy and safety of topically applied Symphytum herb extract cream in the treatment of ankle distortion: results of a randomized controlled clinical double blind study.

    Science.gov (United States)

    Kucera, Miroslav; Barna, Milos; Horácek, Ondrej; Kováriková, Jaroslava; Kucera, Alexander

    2004-11-01

    In a controlled, double blind, randomized multicentre study, the efficacy and safety of the topical comfrey product Traumaplant (10% active ingredient of a 2.5:1 aqueous ethanolic pressed juice of freshly harvested, cultivated comfrey herb (Symphytum x uplandicum NYMAN), corresponding to 25 g of fresh herb per 100 g of cream; n = 104) was tested against a 1% product (corresponding to 2.5 g of fresh comfrey herb in 100 g of cream; n = 99) in 203 patients with acute ankle distortion. With the high concentration, decrease of the scores for pain on active motion, pain at rest and functional impairment was highly significant and clinically relevant on days T3-4 as well as T7 (p < 0.001). Amelioration of swellings as compared to reference was also significant on day 3-4 (p < 0.01). Efficacy was judged good to excellent in 85.6% of cases with verum and in 65.7% of cases with reference on day 3-4. Overall tolerability was excellent.

  10. Resolve. Version 2.5: Flammable Gas Accident Analysis Tool Acceptance Test Plan and Test Results

    International Nuclear Information System (INIS)

    LAVENDER, J.C.

    2000-01-01

    RESOLVE. Version 2 .5 is designed to quantify the risk and uncertainty of combustion accidents in double-shell tanks (DSTs) and single-shell tanks (SSTs). The purpose of the acceptance testing is to ensure that all of the options and features of the computer code run; to verify that the calculated results are consistent with each other; and to evaluate the effects of the changes to the parameter values on the frequency and consequence trends associated with flammable gas deflagrations or detonations

  11. Results of 2007 test beam of AMS-02 Electromagnetic Calorimeter

    Science.gov (United States)

    di Falco, Stefano

    2010-01-01

    The AMS-02 experiment will be delivered by the Space Shuttle Discovery to the ISS in summer 2010. The main goals of the experiment are search for antimatter and dark matter, high precision measurement of charged cosmic ray spectra and fluxes and study of gamma rays, in the GeV to TeV energy range. In AMS-02 the Electromagnetic Calorimeter (ECAL) is required to measure e+,e- and gamma energy and to discriminate electromagnetic showers from hadronic cascades. ECAL is based on a lead/scintillating fiber sandwich, providing a 3D imaging reconstruction of the showers. The electronics equipping the detector has low power consumption, low noise, large dynamic range readout and full double redundancy. The calorimeter successfully got through several space qualification tests concerning the mechanical and thermal stability, the electromagnetic compatibility and radiation hardness. The ECAL Flight Model was calibrated during Summer 2007 in a test beam at CERN, using 6-250 GeV electron and proton beams: angular and energy resolutions, obtained from these data, are reported.

  12. Hanford 100-D Area Biostimulation Treatability Test Results

    Energy Technology Data Exchange (ETDEWEB)

    Truex, Michael J.; Vermeul, Vincent R.; Fritz, Brad G.; Mackley, Rob D.; Mendoza, Donaldo P.; Elmore, Rebecca P.; Mitroshkov, Alexandre V.; Sklarew, Deborah S.; Johnson, Christian D.; Oostrom, Martinus; Newcomer, Darrell R.; Brockman, Fred J.; Bilskis, Christina L.; Hubbard, Susan S.; Peterson, John E.; Williams, Kenneth H.; Gasperikova, E.; Ajo-Franklin, J.

    2009-09-30

    Pacific Northwest National Laboratory conducted a treatability test designed to demonstrate that in situ biostimulation can be applied to help meet cleanup goals in the Hanford Site 100-D Area. In situ biostimulation has been extensively researched and applied for aquifer remediation over the last 20 years for various contaminants. In situ biostimulation, in the context of this project, is the process of amending an aquifer with a substrate that induces growth and/or activity of indigenous bacteria for the purpose of inducing a desired reaction. For application at the 100-D Area, the purpose of biostimulation is to induce reduction of chromate, nitrate, and oxygen to remove these compounds from the groundwater. The in situ biostimulation technology is intended to provide supplemental treatment upgradient of the In Situ Redox Manipulation (ISRM) barrier previously installed in the Hanford 100-D Area and thereby increase the longevity of the ISRM barrier. Substrates for the treatability test were selected to provide information about two general approaches for establishing and maintaining an in situ permeable reactive barrier based on biological reactions, i.e., a biobarrier. These approaches included 1) use of a soluble (miscible) substrate that is relatively easy to distribute over a large areal extent, is inexpensive, and is expected to have moderate longevity; and 2) use of an immiscible substrate that can be distributed over a reasonable areal extent at a moderate cost and is expected to have increased longevity.

  13. Aging test results of an asphalt membrane liner

    International Nuclear Information System (INIS)

    Buelt, J.L.; Barnes, S.M.

    1983-07-01

    The objective of the asphalt aging study described in this report was to determine the expected performance lifetime of a catalytically airblown asphalt membrane as a seepage barrier for inactive uranium mill tailings. The study, conducted by Pacific Northwest Laboratory for the Department of Energy's Uranium Mill Tailings Remedial Action Program, showed through chemical compatibility tests that the asphalt membrane is well suited for this purpose. The chemical compatibility tests were designed to accelerate the aging reactions in the asphalt and to determine the accelerated aging effect. Higher temperatures and oxygen concentrations proved to be effective acceleration parameters. By infrared spectral analysis, the asphalt was determined to have undergone 7 years of equivalent aging in a 3-month period when exposed to 40 0 C and 1.7 atm oxygen pressure. However, the extent of aging was limited to a maximum penetration of 0.5% of the total liner thickness. It was concluded that the liner could be expected to be effective as a seepage barrier for at least 1000 years before the entire thickness of the liner would be degraded

  14. Short-Term Test Results: Multifamily Home Energy Efficiency Retrofit

    Energy Technology Data Exchange (ETDEWEB)

    Lyons, J.

    2013-01-01

    Multifamily deep energy retrofits (DERs) represent great potential for energy savings, while also providing valuable insights on research-generated efficiency measures, cost-effectiveness metrics, and risk factor strategies for the multifamily housing industry. The Bay Ridge project is comprised of a base scope retrofit with a goal of achieving 30% savings (relative to pre-retrofit), and a DER scope with a goal of 50% savings (relative to pre-retrofit). The base scope has been applied to the entire complex, except for one 12-unit building which underwent the DER scope. Findings from the implementation, commissioning, and short-term testing at Bay Ridge include air infiltration reductions of greater than 60% in the DER building; a hybrid heat pump system with a Savings to Investment Ratio (SIR) > 1 (relative to a high efficiency furnace) which also provides the resident with added incentive for energy savings; and duct leakage reductions of > 60% using an aerosolized duct sealing approach. Despite being a moderate rehab instead of a gut rehab, the Bay Ridge DER is currently projected to achieve energy savings ≥ 50% compared to pre-retrofit, and the short-term testing supports this estimate.

  15. Test results of lithium pool-air reaction suppression systems

    International Nuclear Information System (INIS)

    Jeppson, D.W.

    1987-02-01

    Engineered reaction suppression systems were demonstrated to be effective in suppressing lithium pool-air reactions for lithium quantities up to 100 kg. Lithium pool-air reaction suppression system tests were conducted to evaluate suppression system effectiveness for potential use in fusion facilities in mitigating consequences of postulated lithium spills. Small-scale perforated and sacrificial cover plate suppression systems with delayed inert gas purging proved effective in controlling the lithium-air interaction for lithium quantities near 15 kg at initial temperatures up to 450 0 C. A large-scale suppression system with a sacrificial cover, a diverter plate, an inert gas atmosphere, and remotely retrievable catch pans proved effective in controlling lithium pool-air interaction for a 100-kg lithium discharge at an initial temperature of 550 0 C. This suppression system limited the maximum pool temperature to about 600 0 C less than that expected for a similar lithium pool-air reaction without a suppression system. Lithium aerosol release from this large-scale suppression system was a factor of about 10,000 less than that expected for a lithium pool-air reaction with no suppression system. Remote retrieval techniques for lithium cleanup, such as (1) in-place lithium siphoning and overhead crane dismantling, and (2) lithium catch pan removal by use of an overhead crane, were demonstrated as part of this large-scale test

  16. System test results from the GNC experiments on the PRISMA in-orbit test bed

    Science.gov (United States)

    Bodin, Per; Noteborn, Ron; Larsson, Robin; Chasset, Camille

    2011-04-01

    The PRISMA in-orbit test bed will demonstrate guidance, navigation, and control strategies for spacecraft formation flying and rendezvous. The project is funded by the Swedish National Space Board and the prime contractor is the Swedish Space Corporation. The project is further supported by the German Aerospace Center, the Technical University of Denmark, and the French Space Agency. PRISMA was launched on June 15, 2010 and after three weeks of operations, all on-board systems and units have passed an initial commissioning phase. Separation of the two PRISMA satellites from each other is expected by mid-August 2010. PRISMA consists of two spacecraft: MAIN and TARGET. The MAIN spacecraft has full orbit control capability while TARGET is attitude controlled only. The Swedish Space Corporation is responsible for three groups of guidance, navigation, and control experiments. These experiments include GPS- and vision-based formation flying during which the spacecraft will fly in passive as well as forced motion. The three experiments are: autonomous formation flying, proximity operations with final approach/recede maneuvers, and autonomous rendezvous. This paper presents system test results from two of these experiments as obtained with the flight-ready system. The system tests consist of a series of simulations performed on the flight model spacecraft with a large amount of hardware in the loop.

  17. Results of Laboratory Testing of Advanced Power Strips: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Earle, L.; Sparn, B.

    2012-08-01

    This paper describes the results of a laboratory investigation to evaluate the technical performance of advanced power strip (APS) devices when subjected to a range of home entertainment center and home office usage scenarios.

  18. Filtration Understanding: FY10 Testing Results and Filtration Model Update

    Energy Technology Data Exchange (ETDEWEB)

    Daniel, Richard C.; Billing, Justin M.; Burns, Carolyn A.; Peterson, Reid A.; Russell, Renee L.; Schonewill, Philip P.; Shimskey, Rick W.

    2011-04-04

    This document completes the requirements of Milestone 2-4, Final Report of FY10 Testing, discussed in the scope of work outlined in the EM31 task plan WP-2.3.6-2010-1. The focus of task WP 2.3.6 is to improve the U.S. Department of Energy’s (DOE’s) understanding of filtration operations for high-level waste (HLW) to improve filtration and cleaning efficiencies, thereby increasing process throughput and reducing the Na demand (through acid neutralization). Developing the cleaning/backpulsing requirements will produce much more efficient operations for both the Hanford Tank Waste Treatment and Immobilization Plant (WTP) and the Savannah River Site (SRS), thereby significantly increasing throughput by limiting cleaning cycles. The scope of this work is to develop the understanding of filter fouling to allow developing this cleaning/backpulsing strategy.

  19. Test Beam Results with a Full Size sTGC

    CERN Document Server

    Rettie, Sebastien; The ATLAS collaboration

    2014-01-01

    The forthcoming LHC upgrade to high luminosity will increase the background rate in the forward region of the ATLAS Muon Spectrometer (composed of three Big Wheels (BW) and a Small Wheel (SW) on each side of the detector) by approximately a factor of five. With such a rate some of the present Muon Spectrometer detectors in the SW region will produce fake triggers and will therefore be replaced by a New Small Wheel (NSW) composed of small Thin Gap Chamber (sTGC) and Micromegas planes. The aim of the detectors is to reach 100 micrometers position resolution and an online muon track reconstruction with better than 1 mrad precision. A full size sTGC quadruplet has been constructed and equipped with the first prototype of the dedicated front end electronics (VMM1). The performance of the sTGC quadruplet at the Fermilab test beam facility is presented here.

  20. Design and test results of the AMS RICH detector

    CERN Document Server

    Casadei, D.

    2002-01-01

    The AMS-02 detector will operate for at least 3 years on the International Space Station, measuring cosmic ray spectra at about 400 km above sea level over a wide range of geomagnetic latitude. The proximity focusing ring imaging \\v{C}erenkov counter of AMS-02 will measure the particle velocity $\\beta$ with $\\approx 0.1%$ uncertainty, making possible to discriminate Beryllium isotopes up to about 15 GeV/nucl. In addition its charge measurement will allow to study the elemental composition of cosmic rays up to Iron. A prototype of the RICH detector was tested with cosmic rays and on a ion beam accelerated by SPS, at CERN (October 2002).

  1. Short-Term Test Results. Multifamily Home Energy Efficiency Retrofit

    Energy Technology Data Exchange (ETDEWEB)

    Lyons, James [Building America Partnership for Improved Residential Construction (BA-PIRC), Cocoa, FL (United States)

    2013-01-01

    Multifamily deep energy retrofits (DERs) represent great potential for energy savings, while also providing valuable insights on research-generated efficiency measures, cost-effectiveness metrics, and risk factor strategies for the multifamily housing industry. This report describes the Bay Ridge project, a base scope retrofit with a goal of achieving 30% savings (relative to pre-retrofit), and a DER scope with a goal of 50% savings (relative to pre-retrofit). Findings from the short-term testing at Bay Ridge include air infiltration reductions of greater than 60% in the DER building; a hybrid heat pump system with a Savings to Investment Ratio (SIR) > 1 (relative to a high efficiency furnace) which also provides the resident with added incentive for energy savings; and duct leakage reductions of > 60% using an aerosolized duct sealing approach.

  2. Test results, Industrial Solar Technology parabolic trough solar collector

    Energy Technology Data Exchange (ETDEWEB)

    Dudley, V.E. [EG and G MSI, Albuquerque, NM (United States); Evans, L.R.; Matthews, C.W. [Sandia National Labs., Albuquerque, NM (United States)

    1995-11-01

    Sandia National Laboratories and Industrial Solar Technology are cost-sharing development of advanced parabolic trough technology. As part of this effort, several configurations of an IST solar collector were tested to determine the collector efficiency and thermal losses with black chrome and black nickel receiver selective coatings, combined with aluminized film and silver film reflectors, using standard Pyrex{reg_sign} and anti-reflective coated Pyrex{reg_sign} glass receiver envelopes. The development effort has been successful, producing an advanced collector with 77% optical efficiency, using silver-film reflectors, a black nickel receiver coating, and a solgel anti-reflective glass receiver envelope. For each receiver configuration, performance equations were empirically derived relating collector efficiency and thermal losses to the operating temperature. Finally, equations were derived showing collector performance as a function of input insolation value, incident angle, and operating temperature.

  3. Dφ vertex drift chamber construction and test results

    International Nuclear Information System (INIS)

    Clark, A.R.; Goozen, F.; Grudberg, P.; Klopfenstein, C.; Kerth, L.T.; Loken, S.C.; Oltman, E.; Strovink, M.; Trippe, T.G.

    1991-05-01

    A jet-cell based vertex chamber has been built for the D OE experiment at Fermilab and operated in a test beam there. Low drift velocity and diffusion properties were achieved using CO 2 (95%)-ethane(5%) at atmospheric pressure. The drift velocity is found to be consistent with [9.74+8.68(|E|-1.25)] μm/nsec where E is the electric field strength in (kV/cm < |E| z 1.6 kV/cm.) An intrinsic spatial resolution of 60 μm or better for drift distances greater than 2 mm is measured. The track pair efficiency is estimated to be better than 90% for separations greater than 630 μm. 8 refs., 6 figs., 1 tab

  4. EarthCube - Results of Test Governance in Geoscience Cyberinfrastructure

    Science.gov (United States)

    Davis, R.; Allison, M. L.; Keane, C. M.; Robinson, E.

    2016-12-01

    In September 2016, the EarthCube Test Enterprise Governance Project completed its three-year long process to engage the community and test a demonstration governing organization with the goal of facilitating a community-led process on designing and developing a geoscience cyberinfrastructure to transform geoscience research. The EarthCube initiative is making an important transition from creating a coherent community towards adoption and implemention of technologies that can serve scientists working in and across many domains. The emerging concept of a "system of systems" approach to cyberinfrastructure architecture is a critical concept in the EarthCube program, but has not been fully defined. Recommendations from an NSF-appointed Advisory Committee include: a. developing a succinct definition of EarthCube; b. changing the community-elected governance approach towards structured rather than consensus-driven decision-making; c. restructuring the process to articulate program solicitations; and d. producing an effective implementation roadmap. These are seen as prerequisites to adoption of best practices, system concepts, and evolving to a production track. The EarthCube governing body is preparing responses to the Advisory Committee findings and recommendations with a target delivery date of late 2016 but broader involvement may be warranted. We conclude that there is ample justification to continue evolving to a governance framework that facilitates convergence on a system architecture that guides EarthCube activities and plays an influential role in making operational the EarthCube vision of cyberinfrastructure for the geosciences. There is widespread community expectation for support of a multiyear EarthCube governing effort to put into practice the science, technical, and organizational plans that are continuing to emerge. However, the active participants in EarthCube represent a small sub-set of the larger population of geoscientists.

  5. Results of Edge Scatter Testing for a Starshade Mission

    Science.gov (United States)

    Smith, Daniel; Casement, L. Suzanne; Ellis, Scott; Stover, John; Warwick, Steve

    2017-01-01

    In the field of exoplanet detection and characterization, the use of a starshade, an external occulter in front of a telescope at large separations, has been identified as one of the highly promising methods to achieve the necessary high contrast imagery. Control of scattered sunlight from the edges of the starshade into the telescope has been identified as one of the key technology development areas in order to make the starshade feasible. Modeling of the scattered light has resulted in very different results so a campaign of experimentation with edge samples was undertaken to attempt to understand the discrepancies.Here, we present our results from the measurement of select samples of materials which would be suitable for manufacturing the starshade edge, and related models. We have focused on coating metallic samples for ease of fabrication: Titanium, Aluminum, and a Beryllium Copper alloy. Using standard machine shop methods, we fabricated samples which had sharp edges with radius of curvature (RoC) between 15 and 20 μm. We then had these samples coated by two suppliers to evaluate how well these coating types would conform to the edge and provide scatter suppression. The results of scatter measurements of these coated edge samples are presented. These scatter results have been incorporated into a new geometrical model in FRED which includes the details of the starshade mechanical model. This model predicts both the magnitude and distribution of the scattered sunlight in the image plane of a nominal telescope. We present these results, including a first effort at modeling the Solar System at 10 pc as seen by this mission architecture.

  6. Evaluation of the attentional capacities and working memory of early and late blind persons.

    Science.gov (United States)

    Pigeon, Caroline; Marin-Lamellet, Claude

    2015-02-01

    Although attentional processes and working memory seem to be significantly involved in the daily activities (particularly during navigating) of persons who are blind and who use these abilities to compensate for their lack of vision, few studies have investigated these mechanisms in this population. The aim of this study is to evaluate the selective, sustained and divided attention, attentional inhibition and switching and working memory of blind persons. Early blind, late blind and sighted participants completed neuropsychological tests that were designed or adapted to be achievable in the absence of vision. The results revealed that the early blind participants outperformed the sighted ones in selective, sustained and divided attention and working memory tests, and the late blind participants outperformed the sighted participants in selective, sustained and divided attention. However, no differences were found between the blind groups and the sighted group in the attentional inhibition and switching tests. Furthermore, no differences were found between the early and late blind participants in this set of tests. These results suggest that early and late blind persons can compensate for the lack of vision by an enhancement of the attentional and working memory capacities. Copyright © 2014 Elsevier B.V. All rights reserved.

  7. Translating laboratory compaction test results to field scale

    NARCIS (Netherlands)

    Roholl, J.A.; Thienen-Visser, K. van; Breunese, J.N.

    2016-01-01

    In recent studies on the surface subsidence caused by hydrocarbon recovery of the Groningen gas field, the predicted subsidence is overestimated if results of compaction experiments are not corrected by an empirical `upscaling factor'. In order to find an explanation for this `upscaling factor', an

  8. Results of testing improved traditional technique to reduce farmers ...

    African Journals Online (AJOL)

    The weather conditions and crop seasons seem not to be associated with monkeys' crop raiding behaviour in Uluguru Mountains. Therefore, the preliminary results suggest that the use of trained dogs in farms is cheap and can save up to 61.5 % of the current crop losses.al, 1998). The Mountains have outstanding various ...

  9. Up scaling and test results of an advanced Fresnel greenhouse

    NARCIS (Netherlands)

    B.A.J. van Tuijl; H.J.J. Janssen; H.F. de Zwart; Piet Sonneveld; Gert-Jan Swinkels

    2012-01-01

    A greenhouse with Fresnel lenses in the south facing roof and a receiver for concentrated Photovoltaics with water cooling (CPVT system) will result in electrical and thermal energy output from the solar energy excess entering a greenhouse. The PV system converts about half of the direct radiation

  10. VEGETABLE OILS AS SUBSTITUTION FOR DIESEL OIL Test results ...

    African Journals Online (AJOL)

    One result of the esterification process is that the viscosity is reduced to values which also occur with diesel oil. Similarly, the noteable differences between ..... Castor oil may be ot special int.erest 88 it is contrary to other vegetable oila eoluble in alcohol in all proportions and at room temperature. Hence alcohol could be ...

  11. Plutonium recycle test reactor characterization activities and results

    Energy Technology Data Exchange (ETDEWEB)

    Cornwell, B.C.

    1997-05-01

    Report contains results of PRTR core and associated structures characterization performed in January and February of 1997. Radiation survey data are presented, along with recommendations for stabilization activities before transitioning to a decontamination and decommissioning function. Recommendations are also made about handling the waste generated by the stabilization activities, and actions suggested by the Decontamination and Decommissioning organization.

  12. Effects of carvedilol in heart failure due to dilated cardiomyopathy. Results of a double-blind randomized placebo-controlled study (CARIBE study

    Directory of Open Access Journals (Sweden)

    Paulo Roberto Chizzola

    2000-03-01

    Full Text Available OBJECTIVE: To assess the effects of carvedilol in patients with idiopathic dilated cardiomyopathy. METHODS: In a double-blind randomized placebo-controlled study, 30 patients (7 women with functional class II and III heart failure were assessed. Their ages ranged from 28 to 66 years (mean of 43±9 years, and their left ventricular ejection fraction varied from 8% to 35%. Carvedilol was added to the usual therapy of 20 patients; placebo was added to the usual therapy of 10 patients. The initial dose of carvedilol was 12.5 mg, which was increased weekly until it reached 75 mg/day, according to the patient's tolerance. Clinical assessment, electrocardiogram, echocardiogram, and radionuclide ventriculography were performed in the pretreatment phase, being repeated after 2 and 6 months of medication use. RESULTS: A reduction in heart rate (p=0.016 as well as an increase in left ventricular shortening fraction (p=0.02 and in left ventricular ejection fraction (p=0.017 occurred in the group using carvedilol as compared with that using placebo. CONCLUSION: Carvedilol added to the usual therapy for heart failure resulted in better heart function.

  13. COMPARATIVE ANALYSIS OF EFFECTIVENESS AND SAFETY OF PHYTO- AND ANTIBIOTIC THERAPY OF ACUTE BRONCHITIS IN CHILDREN: RESULTS OF A MULTICENTER DOUBLE BLIND RANDOMIZED CLINICAL TRIAL

    Directory of Open Access Journals (Sweden)

    L. S. Namazova-Baranova

    2014-01-01

    Full Text Available Although viruses cause most cases of acute bronchitis, antibacterial drugs are still widely used to treat children with such diseases; this results in development of antibiotic resistance. Therefore, one of the key objectives of clinical medicine is now an effort to reduce unreasonable use of antibacterial agents. A multicenter double blind randomized clinical trial (E-BRO-PCT involved 182 2-6-years-old children and was aimed at assessing effectiveness and safety of phytotherapy (the syrup characterized by a fixed combination of thyme herb and ivy leaf extracts of acute bronchitis. Patients were divided into groups according to the type of therapy: phyto-, antibacterial or multimodal therapy. The level of procalcitonin (PCT – a bacterial inflammation marker – was measured retrospectively in the blood samples of all the children obtained at inclusion to the study. Therapy effectiveness was assessed by means of overall assessment of response to treatment on day 7. The share of children with low PCT and positive response to phytotherapy was comparable to the share of children subjected to antibiotic therapy. This is also true for all the patients included in the study regardless of the PCT level. Phyto- and antibacterial therapy featured a comparable safety profile; however, according to the researchers, the former one came out slightly better. Results of this study convincingly demonstrate that phytotherapy is an effective and well-tolerated type of treatment of acute bronchitis in children. 

  14. Results of zinc injection test for Hamaoka Unit-1

    International Nuclear Information System (INIS)

    Kani, K.; Masuda, H.; Hayashi, Y.; Sudo, S.; Yamazaki, K.

    1998-01-01

    A zinc injection test was preformed at Hamaoka Nuclear Power Station Unit-1 for suppressing radiation dose rate on primary coolant recirculation piping after the replacement of piping. Zinc ion was injected by using injection system where Depleted Zinc Oxide was dissolved in carbonated water. Controllability of the system was sufficient to maintain concentration of zinc in primary water. The concentration of zinc in the primary coolant was controlled from 1 ppb to 5 ppb gradually. The increasing trend of concentration of Co-60 in the coolant was suppressed at zinc concentration of 3 ppb. It is evaluated that the deposition coefficient of Co-60 onto the surface of primary coolant recirculation piping was suppressed to one-third of previous cycle in average, and one-fourth of that just before injection start at zinc concentration of 5 ppb. We concluded that zinc injection is effective for suppressing dose rate on the primary coolant piping and no adverse effect occurs by zinc injection up to 5 ppb in the primary coolant. (J.P.N.)

  15. Results of field testing of waste forms using lysimeters

    International Nuclear Information System (INIS)

    McConnell, J.W. Jr.; Rogers, R.D.

    1988-01-01

    The purpose of the field testing task, using lysimeter arrays, is to expose samples of solidified resin waste to the actual physical, chemical, and microbiological conditions of disposal enviroment. Wastes used in the experiment include a mixture of synthetic organic ion exchange resins and a mixture of organic exchange resins and an inorganic zeolite. Solidification agents used to produce the 4.8-by 7.6-cm cylindrical waste forms used in the study were Portland Type I-II cement and Dow vinyl ester-styrene. Seven of these waste forms were stacked end-to-end and inserted into each lysimeter to provide a 1-L volume. There are 10 lysimeters, 5 at ORNL and 5 at ANL-E. Lysimeters used in this study were designed to be self-contained units which will be disposed at the termination of the 20-year study. Each is a 0.91-by 3.12-m right-circular cylinder divided into an upper compartment, which contains fill material, waste forms, and instrumentation, and an empty lower compartment, which collects leachate. Four lysimeters at each site are filled with soil, while a fifth (used as a control) is filled with inert silica oxide sand. Instrumentation within each lysimeter includes porous cup soil-water samplers and soil moisture/temperature probes. The probes are connected to an on-site data acquisition and storage system (DAS) which also collects data from a field meteorological station located at each site. 9 refs

  16. Memory for environmental sounds in sighted, congenitally blind and late blind adults: evidence for cross-modal compensation.

    Science.gov (United States)

    Röder, Brigitte; Rösler, Frank

    2003-10-01

    Several recent reports suggest compensatory performance changes in blind individuals. It has, however, been argued that the lack of visual input leads to impoverished semantic networks resulting in the use of data-driven rather than conceptual encoding strategies on memory tasks. To test this hypothesis, congenitally blind and sighted participants encoded environmental sounds either physically or semantically. In the recognition phase, both conceptually as well as physically distinct and physically distinct but conceptually highly related lures were intermixed with the environmental sounds encountered during study. Participants indicated whether or not they had heard a sound in the study phase. Congenitally blind adults showed elevated memory both after physical and semantic encoding. After physical encoding blind participants had lower false memory rates than sighted participants, whereas the false memory rates of sighted and blind participants did not differ after semantic encoding. In order to address the question if compensatory changes in memory skills are restricted to critical periods during early childhood, late blind adults were tested with the same paradigm. When matched for age, they showed similarly high memory scores as the congenitally blind. These results demonstrate compensatory performance changes in long-term memory functions due to the loss of a sensory system and provide evidence for high adaptive capabilities of the human cognitive system.

  17. Veggie Hardware Validation Test Preliminary Results and Lessons Learned

    Science.gov (United States)

    Massa, Gioia D.; Dufour, Nicole F.; Smith, T. M.

    2014-01-01

    The Veggie hardware validation test, VEG-01, was conducted on the International Space Station during Expeditions 39 and 40 from May through June of 2014. The Veggie hardware and the VEG-01 experiment payload were launched to station aboard the SpaceX-3 resupply mission in April, 2014. Veggie was installed in an Expedite-the-Processing-of-Experiments-to-Space-Station (ExPRESS) rack in the Columbus module, and the VEG-01 validation test was initiated. Veggie installation was successful, and power was supplied to the unit. The hardware was programmed and the root mat reservoir and plant pillows were installed without issue. As expected, a small amount of growth media was observed in the sealed bags which enclosed the plant pillows when they were destowed. Astronaut Steve Swanson used the wet/dry vacuum to clean up the escaped particles. Water insertion or priming the first plant pillow was unsuccessful as an issue prevented water movement through the quick disconnect. All subsequent pillows were successfully primed, and the initial pillow was replaced with a backup pillow and successfully primed. Six pillows were primed, but only five pillows had plants which germinated. After about a week and a half it was observed that plants were not growing well and that pillow wicks were dry. This indicated that the reservoir was not supplying sufficient water to the pillows via wicking, and so the team reverted to an operational fix which added water directly to the plant pillows. Direct watering of the pillows led to a recovery in several of the stressed plants; a couple of which did not recover. An important lesson learned involved Veggie's bellows. The bellows tended to float and interfere with operations when opened, so Steve secured them to the baseplate during plant tending operations. Due to the perceived intensity of the LED lights, the crew found it challenging to both work under the lights and read crew procedures on their computer. Although the lights are not a safety

  18. DIRECT PHOTOGRAMMETRY USING UAV: TESTS AND FIRST RESULTS

    Directory of Open Access Journals (Sweden)

    F. Chiabrando

    2013-08-01

    Full Text Available In recent years, the quality of high resolution acquisition platforms for geomatic applications has decidedly increased, especially in the performance of the sensors devoted to image acquisition. The small size of these new sensors combined with the increase in resolution allows them to be easily mounted onto Unmanned Aerial Vehicles (UAVs; in particular, calibrated, very-high-resolution digital cameras for photogrammetric purposes such as digital terrain model (DTM and digital surface model (DSM extraction, orthophotos, and map realization have been used. In this case, the UAV performance allows a high quality product to be obtained, considering the pixel size and the accuracy of the DTM/DSM which could be obtained with automatic procedures. Several navigation sensors (GPS/GNSS and IMU-MEMS are embedded into UAVs in order to realize autonomous flight. The quality of these sensors, in terms of accuracy, depends on the model of UAV and its purpose. The navigation solution (position and attitude is estimated by the internal UAV sensor and can be employed to directly georeference the images, in order to produce an quick and easy description and analysis of the overlooked area. This is a good condition for semi-automatic procedures using a bundle-block photogrammetric approach. But is it possible to realize a direct photogrammetry? And what are the limits? Several tests were carried out over different areas and in different conditions using three different UAVs belonging to the Geomatics group of the Politecnico di Torino. In this paper, an investigation of the limits of some commercial UAVs is reported, defining a dedicated procedure to valuate their performance, especially considering the use of UAVs for direct photogrammetry.

  19. Results from tests of TFL Hydragard sampling loop

    International Nuclear Information System (INIS)

    Steimke, J.L.

    1995-03-01

    When the Defense Waste Processing Facility (DWPF) is operational, processed radioactive sludge will be transferred in batches to the Slurry Mix Evaporator (SME), where glass frit will be added and the contents concentrated by boiling. Batches of the slurry mixture are transferred from the SME to the Melter Feed Tank (MFT). Hydragard reg-sign sampling systems are used on the SME and the MFT for collecting slurry samples in vials for chemical analysis. An accurate replica of the Hydragard sampling system was built and tested in the thermal Fluids Laboratory (TFL) to determine the hydragard accuracy. It was determined that the original Hydragard valve frequently drew a non-representative sample stream through the sample vial that ranged from frit enriched to frit depleted. The Hydragard valve was modified by moving the plunger and its seat backwards so that the outer surface of the plunger was flush with the inside diameter of the transfer line when the valve was open. The slurry flowing through the vial accurately represented the composition of the slurry in the reservoir for two types of slurries, different dilution factors, a range of transfer flows and a range of vial flows. It was then found that the 15 ml of slurry left in the vial when the Hydragard valve was closed, which is what will be analyzed at DWPF, had a lower ratio of frit to sludge as characterized by the lithium to iron ratio than the slurry flowing through it. The reason for these differences is not understood at this time but it is recommended that additional experimentation be performed with the TFL Hydragard loop to determine the cause

  20. Advanced Rooftop Control (ARC) Retrofit: Field-Test Results

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Weimin; Katipamula, Srinivas; Ngo, Hung; Underhill, Ronald M.; Taasevigen, Danny J.; Lutes, Robert G.

    2013-07-31

    The multi-year research study was initiated to find solutions to improve packaged equipment operating efficiency in the field. Pacific Northwest National Laboratory (PNNL), with funding from the U.S. Department of Energy’s (DOE’s) Building Technologies Office (BTO) and Bonneville Power Administration (BPA) conducted this research, development and demonstration (RD&D) study. Packaged equipment with constant speed supply fans is designed to provide ventilation at the design rate at all times when the fan is operating as required by building code. Although there are a number of hours during the day when a building may not be fully occupied or the need for ventilation is lower than designed, the ventilation rate cannot be adjusted easily with a constant speed fan. Therefore, modulating the supply fan in conjunction with demand controlled ventilation (DCV) will not only reduce the coil energy but also reduce the fan energy. The objective of this multi-year research, development and demonstration project was to determine the magnitude of energy savings achievable by retrofitting existing packaged rooftop air conditioners with advanced control strategies not ordinarily used for packaged units. First, through detailed simulation analysis, it was shown that significant energy (between 24% and 35%) and cost savings (38%) from fan, cooling and heating energy consumption could be realized when packaged air conditioning units with gas furnaces are retrofitted with advanced control packages (combining multi-speed fan control, integrated economizer controls and DCV). The simulation analysis also showed significant savings for heat pumps (between 20% and 60%). The simulation analysis was followed by an extensive field test of a retrofittable advanced rooftop unit (RTU) controller.

  1. Tank 241-AP-102 Characterization and Grout Product Test Results.

    Energy Technology Data Exchange (ETDEWEB)

    Welsh, T. L. [Hanford Site (HNF), Richland, WA (United States)

    1994-06-02

    Twenty-five samples were obtained from different locations within Tank 241-AP-102. Chemical and radiological analyses were performed on eighteen of these samples. Organic analyses were performed on the remaining seven samples. The results of the statistical analyses of the data indicated that the tank contents were homogeneous. A composite sample was formed using equal volumes of the individual samples. The composite sample was also chemically and radiologically analyzed. Grout specimens were made using the composite sample. The grout product was statistically compared to known criteria.

  2. A double-blind, placebo-controlled test of 2 d of calorie deprivation: effects on cognition, activity, sleep, and interstitial glucose concentrations.

    Science.gov (United States)

    Lieberman, Harris R; Caruso, Christina M; Niro, Philip J; Adam, Gina E; Kellogg, Mark D; Nindl, Bradley C; Kramer, F Matthew

    2008-09-01

    Anecdotal information and limited research suggest that short-term caloric deprivation adversely affects cognition. However, this issue has not been studied using double-blind, placebo-controlled procedures, because the formulation of a calorie-deficient feeding regimen identical to one with calories is impossible using ordinary foods. Therefore, test meals varying in caloric content, but indistinguishable in sensory characteristics, were formulated using hydrocolloid-based gels as the principal structural component. The purpose of this study was to examine the effects of 2 d of near-total caloric deprivation on cognitive function, satiety, activity, sleep, and glucose concentrations in a controlled environment. A double-blind, placebo-controlled crossover study of caloric deprivation was conduced in a controlled environment for 48 h. Cognitive function in 27 healthy young subjects was assessed repeatedly with standardized tests of vigilance, reaction time, learning, memory, logical reasoning, mood, and satiety. Wrist-worn monitors were used to assess ambulatory vigilance, activity, and sleep. Interstitial glucose concentrations were assessed continuously with a minimally invasive monitor. When the subjects received the near calorie-free diets, mean calorie consumption totaled 1311 kJ (313 kcal) over the testing period. During the fully fed treatment sessions, the subjects consumed a mean of 9612 kJ/d (2294 kcal/d), which matched their individual, daily energy requirements. Satiety and interstitial glucose concentrations were lower during the calorie-deprived diet (P effects of calorie deprivation on any aspect of cognitive performance, ambulatory vigilance, activity, or sleep. The mood states assessed, including fatigue, were not affected by calorie deprivation. Cognitive performance, activity, sleep, and mood are not adversely affected in healthy humans by 2 d of calorie-deprivation when the subjects and investigators are unaware of the calorie content of the

  3. MICRO PIN ARRAY DETECTOR (MIPA): FIRST TEST RESULTS.

    Energy Technology Data Exchange (ETDEWEB)

    REHAK,P.; SMITH,G.C.; WARREN,J.B.; YU,B.

    1999-06-28

    A novel gas proportional detector, consisting of an array of pins immersed into a cathode made out of closely packed hexagonals has been developed. The resulting geometry of the detector is 3 dimensional. Electron multiplication is limited to a region in close proximity to the tip of each pin, where the electric field decreases with distance from the pin at a rate faster than 1/r, the rate that exists in a traditional wire chamber. The multiplication region is limited to a small part of the detector volume leading to stability of operation up to high charge gas gains. The amplification region is located far enough from any dielectric surface that the gas gain is insensitive to the charge state of the surface, a significant benefit compared with many other micro-pattern detectors. The microscopic dimensions of the individual pins of the array result in signals whose total duration is about a microsecond. Two identical, but opposite polarity signals are detected, one on the pin and one on the cathode. Both signals can be used by two independent, charge division, read-out systems to obtain unambiguous x-y position information of the primary ionization.

  4. MICRO PIN ARRAY DETECTOR (MIPA): FIRST TEST RESULTS.

    Energy Technology Data Exchange (ETDEWEB)

    REHAK,P.; SMITH,G.C.; WARREN,J.B.; YU,B.

    1999-06-28

    A novel gas proportional detector, consisting of an array of pins immersed into a cathode made out of closely packed hexagonals has been developed. The resulting geometry of the detector is 3 dimensional. Electron multiplication is limited to a region in close proximity to the tip of each pin, where the electric field decreases with distance from the pin at a rate faster than l/r, the rate that exists in a traditional wire chamber. The multiplication region is limited to a small part of the detector volume leading to stability of operation up to high charge gas gains. The amplification region is located far enough from any dielectric surface that the gas gain is insensitive to the charge state of the surface, a significant benefit compared with many other micro-pattern detectors. The microscopic dimensions of the individual pins of the array result in signals whose total duration is about a microsecond. Two identical, but opposite polarity signals are detected, one on the pin and one on the cathode. Both signals can be used by two independent, charge division, read-out systems to obtain unambiguous x-y position information of the primary ionization.

  5. Offset Stream Technology Test-Summary of Results

    Science.gov (United States)

    Brown, Clifford A.; Bridges, James E.; Henderson, Brenda

    2007-01-01

    Statistical jet noise prediction codes that accurately predict spectral directivity for both cold and hot jets are highly sought both in industry and academia. Their formulation, whether based upon manipulations of the Navier-Stokes equations or upon heuristic arguments, require substantial experimental observation of jet turbulence statistics. Unfortunately, the statistics of most interest involve the space-time correlation of flow quantities, especially velocity. Until the last 10 years, all turbulence statistics were made with single-point probes, such as hotwires or laser Doppler anemometry. Particle image velocimetry (PIV) brought many new insights with its ability to measure velocity fields over large regions of jets simultaneously; however, it could not measure velocity at rates higher than a few fields per second, making it unsuitable for obtaining temporal spectra and correlations. The development of time-resolved PIV, herein called TR-PIV, has removed this limitation, enabling measurement of velocity fields at high resolution in both space and time. In this paper, ground-breaking results from the application of TR-PIV to single-flow hot jets are used to explore the impact of heat on turbulent statistics of interest to jet noise models. First, a brief summary of validation studies is reported, undertaken to show that the new technique produces the same trusted results as hotwire at cold, low-speed jets. Second, velocity spectra from cold and hot jets are compared to see the effect of heat on the spectra. It is seen that heated jets possess 10 percent more turbulence intensity compared to the unheated jets with the same velocity. The spectral shapes, when normalized using Strouhal scaling, are insensitive to temperature if the stream-wise location is normalized relative to the potential core length. Similarly, second order velocity correlations, of interest in modeling of jet noise sources, are also insensitive to temperature as well.

  6. Preliminary test results and CFD analysis for Moderator Circulation Test (MCT)

    International Nuclear Information System (INIS)

    Kim, Hyoung Tae

    2015-01-01

    Highlights: • Korea Atomic Energy Research Institute (KAERI) installed the Moderator Circulation Test (MCT) facility. • Velocity profiles for iso-thermal conditions are measured by the Particle Image Velocimetry (PIV). • The PIV measurement results can capture the same flow pattern as that expected in the CANDU6 calandria tank under a momentum dominant flow condition. • More experimental works for the iso-thermal conditions as well as the heating conditions will be performed. • The CFX model will be validated against the PIV measurement data in the future. - Abstract: The moderator flow circulation patterns in CANDU6 reactor are complicated slow flows that significantly vary from buoyancy dominated to inertia dominated patterns. Accurate predictions of flow patterns are essential for accurate calculation of moderator temperature distributions and the related moderator subcooling. The code and its analytical models have therefore to be validated against experiments representative of reactor conditions. Korea Atomic Energy Research Institute (KAERI) installed the Moderator Circulation Test (MCT) facility to simulate the 3 dimensional moderator circulation phenomena in the calandria of CANDU6 reactor and develop the optical measurement system using the Particle Image Velocimetry (PIV). From the present work it is shown that the PIV measurement results can capture the same flow pattern as that expected in the CANDU6 calandria tank under a momentum dominant flow condition, where the inlet jets penetrate the top of the tank and produce a downward flow through the center of the tube columns toward the outlet nozzle, and the flow fields are in symmetric distributions. The measurements of the downward velocities are performed at different locations. The velocity is shown to be axially uniform. The velocity is rapidly decreased as the measurement location is far from the center of the tank, since the downward flow is dominant along the center of the tube columns

  7. [Effects of standardized Myrtol in therapy of acute sinusitis--results of a double-blind, randomized multicenter study compared with placebo].

    Science.gov (United States)

    Federspil, P; Wulkow, R; Zimmermann, T

    1997-01-01

    In the management of non-purulent acute sinusitis, alpha adrenergic substances are administered topically and secretolytics systemically. Antibiotic therapy should be restricted to purulent forms. This study was designed to demonstrate the importance of the maintenance of permanent ventilation and drainage of the sinuses as a therapeutic concept. In a multicentric trial the efficacy and safety of myrtol standardized and another essential oil were investigated in 331 patients with acute sinusitis in comparison to placebo. Three hundred thirty patients were evaluated in an intent-to-treat-analysis and 291 patients remained for statistical analysis. The study was conducted in 16 centers in a double-blind, double-dummy, randomized design versus placebo. During an observation-period of 14 days the patients were treated for 6 +/- 2 days with the respective study medication. With respect to efficacy, both myrtol standardized and the other essential oil proved to be significantly superior to placebo. As to the tolerance, a slight advantage of myrtol standardized was demonstrated in comparison to the other verum substance. These results which do support the value of essential oils like myrtol as an effective treatment in acute, uncomplicated sinusitis instead of antibiotics as first choice, are confirmed by the existing literature.

  8. Effective photoprotection of human skin against infrared A radiation by topically applied antioxidants: results from a vehicle controlled, double-blind, randomized study.

    Science.gov (United States)

    Grether-Beck, Susanne; Marini, Alessandra; Jaenicke, Thomas; Krutmann, Jean

    2015-01-01

    Infrared A radiation (IRA) from solar sunlight contributes to photoaging of human skin, e.g. by upregulating MMP-1 expression in dermal fibroblasts, indicating the need for photoprotection of human skin against IRA. Up to now, however, there has been no controlled study to show that effective protection of human skin against IRA radiation is possible. Here, we have conducted a randomized, controlled, double-blinded prospective study in 30 healthy volunteers to assess the capacity of an SPF 30 sunscreen versus the same sunscreen supplemented with an antioxidant cocktail containing grape seed extract, vitamin E, ubiquinone and vitamin C to protect human skin against IRA radiation-induced MMP-1 upregulation. As expected, exposure to IRA radiation significantly upregulated MMP-1 expression, as compared to unirradiated skin, and this response was significantly reduced, if the SPF30 sunscreen plus the antioxidant cocktail had been applied prior to IRA radiation. In contrast, treatment of human skin with the SPF30 sunscreen alone did not provide significant protection. These results indicate that topically applied antioxidants effectively protect human skin against IRA radiation and that regular sunscreens need to be supplemented with specific antioxidants in order to achieve IRA photoprotection. © 2014 The American Society of Photobiology.

  9. Initial Test Results from a 3-axis Vibrating Ring Gyroscope

    Energy Technology Data Exchange (ETDEWEB)

    Gallacher, B J; Neasham, J A; Burdess, J S; Harris, A J [INSAT University of Newcastle upon Tyne NE1 7RU (United Kingdom)

    2006-04-01

    There are several application areas where the simultaneous measurement of rates of rotation about three mutually orthogonal axes is required. In this paper the principle features of a 3-axis vibrating ring gyroscope are described. The fabrication process for the gyroscope is presented and employs standard MEMS techniques. The modal properties for the ring are measured experimentally using laser vibrometry and electrostatic sensing and compared with the design predictions. In operation as a rate gyroscope it is necessary to excite the primary motion of the gyroscope and control is amplitude. As Q-factors of vibratory gyroscope are typically of the order 10{sup 3}-10{sup 4} slight variations in environmental conditions will perturb the natural frequency of the primary mode significantly. To ensure the primary motion of the gyroscope is maintained with constant amplitude a control scheme employing both frequency tracking and amplitude control is required. An electronic control system using digital signal processing (DSP) has been developed to ensure excitation of the primary motion occurs at resonance with controlled amplitude. The control scheme employs an embedded processor to generate the drive frequency (via a D/A converter) and to monitor the primary vibration (via an A/D converter). Experimental results from the control scheme highlighting its effectiveness over conventional PLL approaches are presented.

  10. Results of Parametric Design Studies of MOX Lead Test Assembly

    Energy Technology Data Exchange (ETDEWEB)

    Pavlovitchev, A.M.; Bychkov, S.A.; Lazarenko, A.A.; Sidorenko, V.D.; Styrin, Y.A.

    1998-12-01

    The parametric studies of MOX LTA design have been executed to choose plutonium content in assembly zones for two options of MOX LTA: 3-zones and Island. For 3-zones (100% Plutonium) MOX LTA the fissile plutonium content composition of 4.2%/3,0%/2% has been chosen. MOX LTA of the chosen compositions has been studied by using multi-assembly configuration that allows investigating of influence of MOX LTA environment: uranium assemblies of different irradiation. Plutonium Island with 54 plutonium pins in the center of MOX LTA has been considered in two modifications: uniform island; and graded island with lower plutonium content in one peripheral row of pins. It is shown that plutonium content in the uniform island cannot exceed 2.7% because of adopted power peaking limitations and therefore this design seems unreasonable for practical use. For graded island the plutonium content composition 3.8%/2.8% with uranium environment of 3.7% U-235 has been chosen. Evolution of assembly power and burnup distributions, inter-pin power and isotopic distributions while fuel irradiating have been analyzed. In addition to the base uranium environment of 3.7%, a set of calculations has been executed for 4.4%. Most of the studies have been executed by the code TVS-M that is at the final stage of licensing and it is to be used in the nearest future as a base instrument for VVER core calculations while using both uranium and MOX fuel. So the obtained results must be considered as preliminary ones and they demand additional analysis and investigations.

  11. Performance Test Results for the Laser-Powered Microthruster

    International Nuclear Information System (INIS)

    Phipps, Claude R.; Luke, James R.; Helgeson, Wesley; Johnson, Richard

    2006-01-01

    Microthrusters are useful for orienting and repositioning small craft above the atmosphere. We report technical results obtained during a successful 5-year program to develop a commercially-viable laser-powered microthruster. Its main advantage is the ability to generate a broad thrust range under programmable electronic control with minimal electrical power. The device applies millisecond-duration diode-laser pulses to a fuel tape to produce an ablation jet. By employing laser-initiated energetic polymers in our ablation fuel tapes, we obtained momentum coupling coefficients as large as 3mN/W of incident laser power, giving a continuous thrust range from 50μN to 10mN. With our standard 30m x 8mm fuel tape, fueled thruster mass is 0.5kg and 50N-s lifetime impulse is achieved. With an order-of-magnitude greater fuel mass, the thruster could accomplish re-entry or substantial orbit-raising of a 10-kg microsatellite. In its usual configuration, specific impulse is 200 seconds, and ablation efficiency, the ratio of exhaust kinetic energy to incident laser optical energy is 180%. We compare performance of several laser-initiated micropropellants which we studied, including polyvinyl nitrate (PVN), glycidyl azide polymer (GAP), and nitrocellulose (NC). All were doped with a laser-absorbing component, either carbon nanopearls with 10nm mean diameter or dyes tuned to the 920-nm laser wavelength but transparent at visible wavelengths. Our demonstrated momentum coupling coefficient is sufficient to levitate a 0.15-kg object with a 500-W laser beam having appropriate characteristics

  12. Results of Parametric Design Studies of MOX Lead Test Assembly

    International Nuclear Information System (INIS)

    Pavlovitchev, A.M.; Bychkov, S.A.; Lazarenko, A.A.; Sidorenko, V.D.; Styrin, Y.A.

    1998-01-01

    The parametric studies of MOX LTA design have been executed to choose plutonium content in assembly zones for two options of MOX LTA: 3-zones and Island. For 3-zones (100% Plutonium) MOX LTA the fissile plutonium content composition of 4.2%/3,0%/2% has been chosen. MOX LTA of the chosen compositions has been studied by using multi-assembly configuration that allows investigating of influence of MOX LTA environment: uranium assemblies of different irradiation. Plutonium Island with 54 plutonium pins in the center of MOX LTA has been considered in two modifications: uniform island; and graded island with lower plutonium content in one peripheral row of pins. It is shown that plutonium content in the uniform island cannot exceed 2.7% because of adopted power peaking limitations and therefore this design seems unreasonable for practical use. For graded island the plutonium content composition 3.8%/2.8% with uranium environment of 3.7% U-235 has been chosen. Evolution of assembly power and burnup distributions, inter-pin power and isotopic distributions while fuel irradiating have been analyzed. In addition to the base uranium environment of 3.7%, a set of calculations has been executed for 4.4%. Most of the studies have been executed by the code TVS-M that is at the final stage of licensing and it is to be used in the nearest future as a base instrument for VVER core calculations while using both uranium and MOX fuel. So the obtained results must be considered as preliminary ones and they demand additional analysis and investigations

  13. Agreement in Measurement of Optic Cup-to-Disc Ratio with Stereo Biomicroscope Funduscopy and Digital Image Analysis: Results from the Nigeria National Blindness and Visual Impairment Survey.

    Science.gov (United States)

    Kyari, Fatima; Gilbert, Clare

    2017-02-01

    To determine agreement in estimations of vertical cup-to-disc ratio (VCDR) between clinical stereo-biomicroscopic funduscopy and digital fundus image analysis. Systematic sampling of 1-in-7 from a sample of 13,591 participants aged ≥40 years gave a subsample who were examined in detail. VCDR was estimated clinically by 60 diopter aspheric lens biomicroscopic funduscopy (c-VCDR) and by digital fundus images (i-VCDR) graded at the Moorfields Eye Hospital Reading Centre. Spearman's correlation coefficient, paired t-test and the Bland-Altman method to assess limits of agreement (LOA) between the two methods were applied. Of 1759 participants in the subsample, 848 participants (48%) with normal frequency doubling technology (FDT) visual fields and data for i-VCDR and c-VCDR in both eyes (n = 1696 eyes) were included in the analysis. By absolute difference of VCDR values for each eye between the two methods, 1585 eyes (94%) differed by ≤0.2. Mean i-VCDR was 0.381 (standard deviation, SD 0.156), and mean c-VCDR 0.321 (SD 0.145). i-VCDRs were significantly larger by a mean difference of 0.061 (SD 0.121; 95% confidence interval, CI, 0.055-0.066; p method were lower limit -0.182 (95% CI -0.192 to -0.172) and upper limit 0.303 (95% CI 0.293-0.313). The 95% LOA intervals narrowed with higher VCDR. Digital image analysis and clinical assessment are two distinct methods to measure VCDR; with larger i-VCDRs in this survey. Applying i-VCDR cut-off values to c-VCDR measurements in the Nigeria Blindness Survey might have underestimated glaucoma prevalence. It is recommended that all participants in glaucoma surveys have VCDR by digital image measurement.

  14. Developmental Outcomes at 24 Months of Age in Toddlers Supplemented with Arachidonic Acid and Docosahexaenoic Acid: Results of a Double Blind Randomized, Controlled Trial

    Directory of Open Access Journals (Sweden)

    Angela M. Devlin

    2017-09-01

    Full Text Available Little is known about arachidonic acid (ARA and docosahexaenoic acid (DHA requirements in toddlers. A longitudinal, double blind, controlled trial in toddlers (n = 133 age 13.4 ± 0.9 months (mean ± standard deviation, randomized to receive a DHA (200 mg/day and ARA (200 mg/day supplement (supplement or a corn oil supplement (control until age 24 months determined effects on neurodevelopment. We found no effect of the supplement on the Bayley Scales of Infant and Toddler Development 3rd Edition (Bayley-III cognitive and language composites and Beery–Buktenica Developmental Test of Visual–Motor Integration (Beery VMI at age 24 months. Supplemented toddlers had higher RBC phosphatidylcholine (PC, phosphatidylethanolamine (PE, and plasma DHA and ARA compared to placebo toddlers at age 24 months. A positive relationship between RBC PE ARA and Bayley III Cognitive composite (4.55 (0.21–9.00, B (95% CI, p = 0.045 in supplemented boys, but not in control boys, was observed in models adjusted for baseline fatty acid, maternal non-verbal intelligence, and BMI z-score at age 24 months. A similar positive relationship between RBC PE ARA and Bayley III Language composite was observed for supplemented boys (11.52 (5.10–17.94, p < 0.001 and girls (11.19 (4.69–17.68, p = 0.001. These findings suggest that increasing the ARA status in toddlers is associated with better neurodevelopment at age 24 months.

  15. [Wound healing effects of a Symphytum herb extract cream (Symphytum x uplandicum NYMAN: ): results of a randomized, controlled double-blind study].

    Science.gov (United States)

    Barna, Milos; Kucera, Alexander; Hladícova, Marie; Kucera, Miroslav

    2007-01-01

    Wound healing effects of a topically applied preparation (Traumaplant) containing a concentrate (10 % active ingredient) from the aerial parts of medicinal comfrey (Symphytum x uplandicum NYMAN: ) were examined in a randomized clinical double-blind study including 278 patients with fresh abrasions (verum: n = 137), among them 64 patients of up to 20 years of age (verum n = 29, reference product n = 35). An otherwise identical low-dose preparation (1 % active ingredient; n = 141) was used as a reference. After 2-3 days of application of the study medication a highly significantly and clinically relevantly faster initial reduction of wound size of 49 + or - 19 % versus 29 + or - 13 % per day in favour of verum (p < 5x10(-21)) was found. From linear regression time to complete healing was determined to be 2.97 days faster with verum than with reference (4.08 vs. 7.05 days, p = 7.4 x 10(-45) in the t-Test comparison of regression lines). The physicians rated efficacy as good to very good in 93.4 % of cases, as compared to 61.7 % in the group treated with the reference product (p = 2 x 10(-11)). On a scale of 0-100 verum was rated with 84.4 + or - 10.1 points by the patients themselves. The reference product was rated with 65.5 + or - 24.8 points (p = 6.1 x 10(-18)). In subgroup analyses no significant influence of abrasion area, gender and age on healing effects was found, albeit a tendency towards better effects with increasing age was observed. No adverse effects or problems with drug tolerability occurred. Specifically, cutaneous reactions were observed in none of the patients throughout the 10 day observation phase. Symphytum herb extract can be attributed distinct wound healing effects, effects that can explicitly be used in paediatry.

  16. Optimal blind quantum computation.

    Science.gov (United States)

    Mantri, Atul; Pérez-Delgado, Carlos A; Fitzsimons, Joseph F

    2013-12-06

    Blind quantum computation allows a client with limited quantum capabilities to interact with a remote quantum computer to perform an arbitrary quantum computation, while keeping the description of that computation hidden from the remote quantum computer. While a number of protocols have been proposed in recent years, little is currently understood about the resources necessary to accomplish the task. Here, we present general techniques for upper and lower bounding the quantum communication necessary to perform blind quantum computation, and use these techniques to establish concrete bounds for common choices of the client's quantum capabilities. Our results show that the universal blind quantum computation protocol of Broadbent, Fitzsimons, and Kashefi, comes within a factor of 8/3 of optimal when the client is restricted to preparing single qubits. However, we describe a generalization of this protocol which requires exponentially less quantum communication when the client has a more sophisticated device.

  17. Introduction of peanuts in younger siblings of children with peanut allergy: a prospective, double-blinded assessment of risk, of diagnostic tests, and an analysis of patient preferences.

    Science.gov (United States)

    Bégin, P; Graham, F; Killer, K; Paradis, J; Paradis, L; Des Roches, A

    2016-12-01

    The prevalence of peanut allergy in younger siblings of children with peanut allergy has been reported between 7% and 8.5%, but the anaphylactic risk at the time of introduction is currently unknown, which limits our ability to best counsel parents on this issue. To determine the risk of anaphylaxis and working parameters of allergy testing in this context. One hundred and fifty-four peanut-naïve younger siblings of peanut-allergic children underwent double-blinded skin testing, followed by parent-led peanut introduction. Questionnaires were dispensed to parents to investigate preferences with regard to peanut introduction in this subgroup. Eight participants (5.2%) presented unequivocal IgE-mediated reactions to peanut upon introduction, including five anaphylaxes. These participants were significantly older compared to the rest of the cohort (median 4.0 vs 1.9 years, P = 0.04). The negative predictive value of skin prick test with peanut extract and peanut butter and of specific IgE was 99%, 100%, and 100%, respectively. Six peanut-tolerant participants had positive peanut allergy tests. The option of introducing at home without prior skin testing was associated with high levels of anxiety (median 8.4 on 10-point Likert scale) when compared to supervised introduction (median 3.8, P < 0.0001) or home introduction after negative skin test (median 4.3, P < 0.0001). There is an increased risk of anaphylaxis upon peanut introduction in siblings of children with peanut allergy, and parents are reluctant to introduce at home without testing. Allergy testing prior to introduction is negative in over 90% of cases and carries a high negative predictive value. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  18. Do mobile phone base stations affect sleep of residents? Results from an experimental double-blind sham-controlled field study.

    Science.gov (United States)

    Danker-Hopfe, Heidi; Dorn, Hans; Bornkessel, Christian; Sauter, Cornelia

    2010-01-01

    The aim of the present double-blind, sham-controlled, balanced randomized cross-over study was to disentangle effects of electromagnetic fields (EMF) and non-EMF effects of mobile phone base stations on objective and subjective sleep quality. In total 397 residents aged 18-81 years (50.9% female) from 10 German sites, where no mobile phone service was available, were exposed to sham and GSM (Global System for Mobile Communications, 900 MHz and 1,800 MHz) base station signals by an experimental base station while their sleep was monitored at their homes during 12 nights. Participants were randomly exposed to real (GSM) or sham exposure for five nights each. Individual measurement of EMF exposure, questionnaires on sleep disorders, overall sleep quality, attitude towards mobile communication, and on subjective sleep quality (morning and evening protocols) as well as objective sleep data (frontal EEG and EOG recordings) were gathered. Analysis of the subjective and objective sleep data did not reveal any significant differences between the real and sham condition. During sham exposure nights, objective and subjective sleep efficiency, wake after sleep onset, and subjective sleep latency were significantly worse in participants with concerns about possible health risks resulting from base stations than in participants who were not concerned. The study did not provide any evidence for short-term physiological effects of EMF emitted by mobile phone base stations on objective and subjective sleep quality. However, the results indicate that mobile phone base stations as such (not the electromagnetic fields) may have a significant negative impact on sleep quality. (c) 2010 Wiley-Liss, Inc.

  19. Sensory augmentation for the blind

    Directory of Open Access Journals (Sweden)

    Silke Manuela Kärcher

    2012-03-01

    Full Text Available Enacted theories of consciousness conjecture that perception and cognition arise from an active experience of the regular relations that are tying together the sensory stimulation of different modalities and associated motor actions. Previous experiments investigated this concept by employing the technique of sensory substitution. Building on these studies, here we test a set of hypotheses derived from this framework and investigate the utility of sensory augmentation in handicapped people. We provide a late blind subject with a new set of sensorimotor laws: A vibro-tactile belt continually signals the direction of magnetic north. The subject completed a set of behavioral tests before and after an extended training period. The tests were complemented by questionnaires and interviews. This newly supplied information improved performance on different time scales. In a pointing task we demonstrate an instant improvement of performance based on the signal provided by the device. Furthermore, the signal was helpful in relevant daily tasks, often complicated for the blind, such as keeping a direction over longer distances or taking shortcuts in familiar environments. A homing task with an additional attentional load demonstrated a significant improvement after training. The subject found the directional information highly expedient for the adjustment of his inner maps of familiar environments and describes an increase in his feeling of security when exploring unfamiliar environments with the belt. The results give evidence for a firm integration of the newly supplied signals into the behavior of this late blind subject with better navigational performance and more courageous behavior in unfamiliar environments. Most importantly, the complementary information provided by the belt lead to a positive emotional impact with enhanced feeling of security. This experimental approach demonstrates the potential of sensory augmentation devices for the help of

  20. 14 CFR 63.12a - Refusal to submit to an alcohol test or to furnish test results.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Refusal to submit to an alcohol test or to furnish test results. 63.12a Section 63.12a Aeronautics and Space FEDERAL AVIATION ADMINISTRATION... § 63.12a Refusal to submit to an alcohol test or to furnish test results. A refusal to submit to a test...

  1. Blind Adolescents' Perceptions of Parental Attitudes.

    Science.gov (United States)

    Agarwal, Rita; Piplani, Rashmi

    1990-01-01

    This study examined the perception of parental attitudes of 50 blind adolescents in northern India. Results indicated that blind girls perceived their parents as being more accepting and less rejecting than did blind boys, a result explained by culturally determined differences in social sex roles. (DB)

  2. Occupant satisfaction with two blind control strategies

    DEFF Research Database (Denmark)

    Karlsen, Line Røseth; Heiselberg, Per Kvols; Bryn, Ida

    2015-01-01

    Highlights •Occupant satisfaction with two blind control strategies has been studied. •Control based on cut-off position of slats was more popular than closed slats. •Results from the study are helpful in development of control strategies for blinds. •The results give indications of how blinds...

  3. Prevalence and causes of low vision and blindness in the blind population supported by the Yazd Welfare Organization

    Directory of Open Access Journals (Sweden)

    F Ezoddini - Ardakani

    2006-01-01

    Full Text Available Introduction: In 1995, the World Health Organization (WHO estimated that there were 37.1 million blind people worldwide. It has subsequently been reported that 110 million people have severely impaired vision, hence are at great risk of becoming blind. Watkins predicted an annual increase of about two million blind worldwide. This study was designed to investigate the causes of blindness and low vision in the blind population supported by the welfare organization of Yazd, Iran. Methods: This clinical descriptive cross-sectional study was done from January to September, 2003. In total, 109 blind patients supported by the welfare organization were included in this study. All data was collected by standard methods using questionnaire, interview and specific examination. The data included; demographic characteristics, clinical states, ophthalmic examination, family history and the available prenatal information. The data were analyzed by SPSS software and chi square test. Results: Of total patients, 73 cases were male (67% and 36 were female (33%. The median age was 24.6 years (range one month to 60 years. More than half of the cases (53.2% could be diagnosed in children less than one year of age. In total, 79 patients (88.1% were legally blind of which 23 cases (29.1% had no light perception (NLP. The most common causes of blindness were retinitis pigmentosa (32.1% followed by ocular dysgenesis (16.5%. Conclusion: Our data showed that more than half of the blindness cases occur during the first year of life. The most common cause of blindness was retinitis pigmentosa followed by ocular dysgenesis, cataract and glaucoma, respectively.

  4. [Epidural anaesthesia: Simulated intravascular test dose with S(+) ketamine, lidocaine and adrenaline. A prospective, randomized, double blind and placebo controlled study].

    Science.gov (United States)

    Higueras, R; Errando, C L; Soriano-Bru, J L

    2015-02-01

    The use of a test dose in epidural anaesthesia is a safety recommendation. However specificity and sensitivity of the drugs used with this indication have been not conclusive. The main objective of this study was to compare the effectiveness and the adverse effects of a simulated intravascular test dose of adrenaline, lidocaine and S(+)-ketamine. A prospective, randomized, double blinded, placebo controlled study was designed. ASA I patients scheduled for elective surgery were included. These were randomized to the following study groups: S(+)-ketamine 0.5 mg.kg-1 (S+K group), 5% lidocaine 1.5 mg.kg-1 (L5% group), adrenaline 15μg (ADR group), and physiological saline 3 ml (SF group; control group). An evaluation was made during the first 15 minutes after the study drug was administered. Variables including heart rate (HR) systolic and diastolic blood pressure (sBP and dBP), mean arterial pressure (MAP), and SpO2 were recorded at 0 min (baseline) and at 2, 5, 8, 10 and 15 minutes after drug injection. An increase of at least 20 beats per minute (bpm) in relation to the baseline measurement was considered a positive result, as was an increase sBP >15 mmHg. The clinical effects described as related to iv injection of the study drugs recorded were: sedation-hypnosis, dizziness, nystagmus, metallic taste perception, perioral or facial paresthesias, tinnitus, as well as any other effect the patients mentioned. Sensitivity and specificity were calculated as was the percent increase in the parameters in order to see if these were clinically useful. A total of 80 patients, 20 per group, were included. The sBP, dBP, and MAP were significantly raised at the 2, 5, 8 and 10 minutes measurements in the S(+)K group compared to the rest of the groups (P<.05), as well as HR in the 2, 5, 8, 10 and 15 minute measurements in the S(+)K compared to the rest of the groups (P<.05). Sensitivity and specificity were high, and significant in the S(+)K group from minute 2 to minute 8

  5. Correlation Results for a Mass Loaded Vehicle Panel Test Article Finite Element Models and Modal Survey Tests

    Science.gov (United States)

    Maasha, Rumaasha; Towner, Robert L.

    2012-01-01

    High-fidelity Finite Element Models (FEMs) were developed to support a recent test program at Marshall Space Flight Center (MSFC). The FEMs correspond to test articles used for a series of acoustic tests. Modal survey tests were used to validate the FEMs for five acoustic tests (a bare panel and four different mass-loaded panel configurations). An additional modal survey test was performed on the empty test fixture (orthogrid panel mounting fixture, between the reverb and anechoic chambers). Modal survey tests were used to test-validate the dynamic characteristics of FEMs used for acoustic test excitation. Modal survey testing and subsequent model correlation has validated the natural frequencies and mode shapes of the FEMs. The modal survey test results provide a basis for the analysis models used for acoustic loading response test and analysis comparisons

  6. Golimumab in patients with active rheumatoid arthritis who have previous experience with tumour necrosis factor inhibitors: results of a long-term extension of the randomised, double-blind, placebo-controlled GO-AFTER study through week 160

    NARCIS (Netherlands)

    Smolen, Josef S.; Kay, Jonathan; Landewé, Robert B. M.; Matteson, Eric L.; Gaylis, Norman; Wollenhaupt, Jurgen; Murphy, Frederick T.; Zhou, Yiying; Hsia, Elizabeth C.; Doyle, Mittie K.

    2012-01-01

    The aim of this study was to assess long-term golimumab therapy in patients with rheumatoid arthritis (RA) who discontinued previous tumour necrosis factor alpha (TNFα) inhibitor(s) for any reason. Results through week 24 of this multicentre, randomised, double-blind, placebo-controlled study of

  7. Evaluation of LLTR Series II tests A-1A and A-1B test results

    International Nuclear Information System (INIS)

    Shoopak, B.F.; Amos, J.C.; Norvell, T.J.

    1980-03-01

    The standard methodology, with minor modifications provides conservative yet realistic predictions of leaksite and other sodium system pressures in the LLTR Series II vessel and piping. The good agreement between predicted and measured pressures indicates that the TRANSWRAP/RELAP modeling developed from the Series I tests is applicable to larger scale units prototypical of the Clinch River steam generator design. Calculated sodium system pressures are sensitive to several modeling parameters including rupture disc modeling, acoustic velocity in the test vessel, and flow rate from the rupture tube. The acoustic velocity which produced best agreement with leaksite pressures was calculated based on the shroud diameter and shroud wall thickness. The corresponding rupture tube discharge coefficient was that of the standard design methodology developed from Series I testing. As found in Series I testing, the Series II data suggests that the leading edge of the flow in the relief line is two phase for a single, doubled-ended guillotine tube rupture. The steam generator shroud acts as if it is relatively transparent to the transmission of radial pressures to the vessel wall. Slightly lower sodium system maximum pressures measured during Test A-1b compared to Test A-1a are attributed to premature failure (failure at a lower pressure) of the rupture disc in contact with the sodium for test A-1b. The delay in failure of the second disc in Test A-1b, which was successfully modeled with TRANSWRAP, is attributed to the limited energy in the nitrogen injection

  8. Preliminary test results and CFD analysis for moderator circulation test at Korea

    International Nuclear Information System (INIS)

    Kim, H.T.; Im, S.H.; Sung, H.J.; Seo, H.; Bang, I.C.

    2014-01-01

    Korea Atomic Energy Research Institute (KAERI) is carrying out a scaled-down moderator test program to simulate the CANDU6 moderator circulation phenomena during steady state operation and accident conditions. This research program includes the construction of the Moderator Circulation Test (MCT) facility, production of the validation data for self-reliant CFD tools, and development of optical measurement system using the Particle Image Velocimetry (PIV). The MCT facility includes a primary circulation loop (pipe lines, a primary side pump, a heat exchanger, valves, flow meters) and a secondary side loop (pipe lines, a secondary side pump, and an external cooling tower). The loop leakage test and non-heating test are performed in the present work. In the present work the PIV technique is used to measure the velocity distributions in the scaled moderator tank of MCT under iso-thermal test conditions. The preliminary PIV measurement data are obtained and compared with CFX code predictions. (author)

  9. 10 CFR 707.13 - Medical review of results of tests for illegal drug use.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Medical review of results of tests for illegal drug use... Procedures § 707.13 Medical review of results of tests for illegal drug use. (a) All test results shall be... with legal and non-abusive drug use, the MRO will certify that the test results do not meet the...

  10. Avoidance test with Eisenia fetida as indicator for the habitat function of soils. Results of a laboratory comparison test

    Energy Technology Data Exchange (ETDEWEB)

    Hund-Rinke, K. [Fraunhofer Inst. for Molecular Biology and Applied Ecology, Schmallenberg (Germany); Achazi, R.; Warnecke, D. [Free Univ. of Berlin, Inst. for Biology, Berlin (Germany); Roembke, J. [ECT Oekotoxikologie GmbH, Floersheim (Germany)

    2003-07-01

    Intention, Goal, Scope, Background. The habitat function of soils is often assessed using the reproduction test with Eisenia fetida. As this test is rather labour-intensive, an alternative is needed which is less cost-intensive in terms of duration and workload, but gives reasonable results. The avoidance test with E. fetida is a suitable screening test meeting these criteria. However, before a novel test system can be generally recommended it has to be ensured that comparable results are acquired from different laboratories on the basis of the respective test guideline. Objective. The avoidance test with E. fetida was performed as laboratory comparison test. The results were compared with those of the earthworm acute and reproduction tests carried out with the same soils. Methods. The three tests were performed by three laboratories using eight contaminated soils and three control soils. The contaminated soils were mixed with the control soils to obtain different concentrations of the contamination. (orig.)

  11. Intravenous acetaminophen is superior to ketamine for postoperative pain after abdominal hysterectomy: results of a prospective, randomized, double-blind, multicenter clinical trial

    Directory of Open Access Journals (Sweden)

    Faiz HR

    2014-01-01

    Full Text Available Hamid Reza Faiz,1 Poupak Rahimzadeh,1 Ognjen Visnjevac,2 Behzad Behzadi,1 Mohammad Reza Ghodraty,1 Nader D Nader2 1Iran University of Medical Sciences, Tehran, Iran; 2VA Western NY Healthcare System, University at Buffalo, Buffalo, NY, USA Background: In recent years, intravenously (IV administered acetaminophen has become one of the most common perioperative analgesics. Despite its now-routine use, IV acetaminophen's analgesic comparative efficacy has never been compared with that of ketamine, a decades-old analgesic familiar to obstetricians, gynecologists, and anesthesiologists alike. This double-blind clinical trial aimed to evaluate the analgesic effects of ketamine and IV acetaminophen on postoperative pain after abdominal hysterectomy. Methods: Eighty women aged 25–70 years old and meeting inclusion and exclusion criteria were randomly allocated into two groups of 40 to receive either IV acetaminophen or ketamine intraoperatively. Postoperatively, each patient had patient-controlled analgesia. Pain and sedation (Ramsay Sedation Scale were documented based on the visual analog scale in the recovery room and at 4 hours, 6 hours, 12 hours, and 24 hours after the surgery. Hemodynamic changes, adverse medication effects, and the need for breakthrough meperidine were also recorded for both groups. Data were analyzed by repeated-measures analysis of variance. Results: Visual analog scale scores were significantly lower in the IV acetaminophen group at each time point (P<0.05, and this group required significantly fewer doses of breakthrough analgesics compared with the ketamine group (P=0.039. The two groups had no significant differences in terms of adverse effects. Conclusion: Compared with ketamine, IV acetaminophen significantly improved postoperative pain after abdominal hysterectomy. Keywords: intravenous acetaminophen, abdominal hysterectomy, ketamine, analgesia, postoperative pain

  12. Preliminary aggregate safety and immunogenicity results from three trials of a purified inactivated Zika virus vaccine candidate: phase 1, randomised, double-blind, placebo-controlled clinical trials.

    Science.gov (United States)

    Modjarrad, Kayvon; Lin, Leyi; George, Sarah L; Stephenson, Kathryn E; Eckels, Kenneth H; De La Barrera, Rafael A; Jarman, Richard G; Sondergaard, Erica; Tennant, Janice; Ansel, Jessica L; Mills, Kristin; Koren, Michael; Robb, Merlin L; Barrett, Jill; Thompson, Jason; Kosel, Alison E; Dawson, Peter; Hale, Andrew; Tan, C Sabrina; Walsh, Stephen R; Meyer, Keith E; Brien, James; Crowell, Trevor A; Blazevic, Azra; Mosby, Karla; Larocca, Rafael A; Abbink, Peter; Boyd, Michael; Bricault, Christine A; Seaman, Michael S; Basil, Anne; Walsh, Melissa; Tonwe, Veronica; Hoft, Daniel F; Thomas, Stephen J; Barouch, Dan H; Michael, Nelson L

    2017-12-04

    A safe, effective, and rapidly scalable vaccine against Zika virus infection is needed. We developed a purified formalin-inactivated Zika virus vaccine (ZPIV) candidate that showed protection in mice and non-human primates against viraemia after Zika virus challenge. Here we present the preliminary results in human beings. We did three phase 1, placebo-controlled, double-blind trials of ZPIV with aluminium hydroxide adjuvant. In all three studies, healthy adults were randomly assigned by a computer-generated list to receive 5 μg ZPIV or saline placebo, in a ratio of 4:1 at Walter Reed Army Institute of Research, Silver Spring, MD, USA, or of 5:1 at Saint Louis University, Saint Louis, MO, USA, and Beth Israel Deaconess Medical Center, Boston, MA, USA. Vaccinations were given intramuscularly on days 1 and 29. The primary objective was safety and immunogenicity of the ZPIV candidate. We recorded adverse events and Zika virus envelope microneutralisation titres up to day 57. These trials are registered at ClinicalTrials.gov, numbers NCT02963909, NCT02952833, and NCT02937233. We enrolled 68 participants between Nov 7, 2016, and Jan 25, 2017. One was excluded and 67 participants received two injections of Zika vaccine (n=55) or placebo (n=12). The vaccine caused only mild to moderate adverse events. The most frequent local effects were pain (n=40 [60%]) or tenderness (n=32 [47%]) at the injection site, and the most frequent systemic reactogenic events were fatigue (29 [43%]), headache (26 [39%]), and malaise (15 [22%]). By day 57, 52 (92%) of vaccine recipients had seroconverted (microneutralisation titre ≥1:10), with peak geometric mean titres seen at day 43 and exceeding protective thresholds seen in animal studies. The ZPIV candidate was well tolerated and elicited robust neutralising antibody titres in healthy adults. Departments of the Army and Defense and National Institute of Allergy and Infectious Diseases. Copyright © 2017 Elsevier Ltd. All rights reserved.

  13. Does prophylactic treatment with proteolytic enzymes reduce acute toxicity of adjuvant pelvic irradiation? Results of a double-blind randomized trial

    International Nuclear Information System (INIS)

    Martin, Thomas; Uhder, Kerstin; Kurek, Ralf; Roeddiger, Sandra; Schneider, Lida; Vogt, Hans-Georg; Heyd, Reinhard; Zamboglou, Nikolaos

    2002-01-01

    Purpose: Does prophylactic treatment with proteolytic enzymes reduce acute toxicity of adjuvant pelvic radiotherapy? Material and methods: Fifty-six patients with an indication for adjuvant pelvic irradiation after curative surgery were double-blind randomized. All patients took 3x4 capsules study medication daily during radiotherapy. Twenty-eight patients in the enzyme group (EG) received capsules containing papain, trypsin and chymotrypsin, 28 in the placebo group (PG) received placebo capsules. All patients were irradiated with 5x1.8 Gy weekly to 50.4 Gy using four-field-box technique after CT-based planning. Primary objective was the grade of diarrhea, nausea, vomiting, fatigue and epitheliolysis during radiotherapy. Secondary objectives were the number of supportive medications and treatment interruptions due to acute toxicity. Results: None/mild diarrhea: 43% EG, 64% PG. Moderate/severe diarrhea: 57% EG, 36% PG (P=0.11). Mean duration: 11 days in EG, 10 days in PG. None/mild nausea: 93% EG, 93% PG. Moderate/severe nausea: 7% EG, 7% PG. None/mild vomiting: 100% EG, 97% PG. None/mild fatigue: 82% EG, 93% PG. Moderate/severe fatigue: 18% EG, 7% PG (P=0.23). None/mild epitheliolysis: 75% EG, 93% PG. Moderate/severe epitheliolysis: 25% EG, 7% PG (P=0.16). Treatment interruption (mean days): 2.44 in EG, 1.46 in PG. Number of supportive medication: 29 in EG, 19 in PG. Conclusions: The prophylactic use of proteolytic enzymes does not reduce acute toxicities, treatment interruptions and number of supportive medication and therefore does not improve tolerance of adjuvant pelvic radiotherapy

  14. Efficacy of a comfrey root extract ointment in comparison to a diclofenac gel in the treatment of ankle distortions: results of an observer-blind, randomized, multicenter study.

    Science.gov (United States)

    Predel, H G; Giannetti, B; Koll, R; Bulitta, M; Staiger, C

    2005-11-01

    In the treatment of minor blunt injuries several topical drugs are known to have anti-inflammatory and analgesic properties. They represent, however, two fundamentally different major pharmacological therapy approaches: the "chemical-synthetical" and the "phytotherapeutical" approach. The main objective of this trial (CODEC_2004) was to compare the efficacy and tolerability of an ointment of Comfrey extract (Extr. Rad. Symphyti) with that of a Diclofenac gel in the treatment of acute unilateral ankle sprain (distortion). In a single-blind, controlled, randomized, parallel-group, multicenter and confirmatory clinical trial outpatients with acute unilateral ankle sprains (n=164, mean age 29.0 years, 47.6% female) received either a 6 cm long ointment layer of Kytta-Salbe f (Comfrey extract) (n=82) or of Diclofenac gel containing 1.16 g of diclofenac diethylamine salt (n=82) for 7 +/- 1 days, four times a day. Primary variable was the area-under-the-curve (AUC) of the pain reaction to pressure on the injured area measured by a calibrated caliper (tonometer). Secondary variables were the circumference of the joint (swelling; figure-of-eight method), the individual spontaneous pain sensation at rest and at movement according to a Visual Analogue Scale (VAS), the judgment of impaired movements of the injured joint by the method of "neutral-zero", consumption of rescue medication (paracetamol), as well as the global efficacy evaluation and the global assessment of tolerability (both by physician and patient, 4 ranks). In this study the primary variable was also to be validated prospectively. It was confirmatorily shown that Comfrey extract is non-inferior to diclofenac. The 95% confidence interval for the AUC (Comfrey extract minus Diclofenac gel) was 19.01-103.09h*N/cm2 and was completely above the margin of non-inferiority. Moreover, the results of the primary and secondary variables indicate that Comfrey extract may be superior to Diclofenac gel.

  15. Test results of Run-1 and Run-2 in steam generator safety test facility (SWAT-3)

    International Nuclear Information System (INIS)

    Kurihara, A.; Yatabe, Toshio; Tanabe, Hiromi; Hiroi, Hiroshi

    2003-07-01

    Large leak sodium-water reaction tests were carried out using SWAT-1 rig and SWAT-3 facility in Power Reactor and Nuclear Fuel Development Corporation (PNC) O-arai Engineering Center to obtain the data on the design of the prototype LMFBR Monju steam generator against a large leak accident. This report provides the results of SWAT-3 Runs 1 and 2. In Runs 1 and 2, the heat transfer tube bundle of the evaporator, fabricated by TOSHIBA/IHI, were used, and the pressure relief line was located at the top of evaporator. The water injection rates in the evaporator were 6.7 kg/s and 14.2 (initial)-9.7 kg/s in Runs 1 and 2 respectively, which corresponded to 3.3 tubes and 7.1 (initial)-4.8 tubes failure in actual size system according to iso-velocity modeling. Approximately two hundreds of measurement points were provided to collect data such as pressure, temperature, strain, sodium level, void, thrust load, acceleration, displacement, flow rate, and so on in each run. Initial spike pressures were 1.13 MPa and 2.62 MPa nearest to injection point in Runs 1 and 2 respectively, and the maximum quasi-steady pressures in evaporator were 0.49 MPa and 0.67 MPa in Runs 1 and 2. No secondary tube failure was observed. The rupture disc of evaporator (RD601) burst at 1.1s in Run-1 and at 0.7s in Run-2 after water injected, and the pressure relief system was well-functioned though a few items for improvement were found. (author)

  16. Subcutaneous golimumab for children with active polyarticular-course juvenile idiopathic arthritis : results of a multicentre, double-blind, randomised-withdrawal trial

    NARCIS (Netherlands)

    Brunner, Hermine I; Ruperto, Nicolino; Tzaribachev, Nikolay; Horneff, Gerd; Chasnyk, Vyacheslav G.; Panaviene, Violeta Vladislava; Abud-Mendoza, Carlos; Reiff, Andreas; Alexeeva, Ekaterina; Rubio-Pérez, Nadina; Keltsev, Vladimir; Kingsbury, Daniel J.; Del Rocio Maldonado Velázquez, Maria; Nikishina, Irina; Silverman, Earl D.; Joos, Rik; Smolewska, Elzbieta; Bandeira, Márcia; Minden, Kirsten; van Royen-Kerkhof, Annet; Emminger, Wolfgang; Foeldvari, Ivan; Lauwerys, Bernard R.; Sztajnbok, Flavio; Gilmer, Keith E.; Xu, Zhenhua; Leu, Jocelyn H.; Kim, Lilianne; Lamberth, Sarah L.; Loza, Matthew J.; Lovell, Daniel J.; Martini, Alberto

    2018-01-01

    OBJECTIVE: This report aims to determine the safety, pharmacokinetics (PK) and efficacy of subcutaneous golimumab in active polyarticular-course juvenile idiopathic arthritis (polyJIA). METHODS: In this three-part randomised double-blinded placebo-controlled withdrawal trial, all patients received

  17. The angiotensin II receptor antagonist telmisartan reduces urinary albumin excretion in patients with isolated systolic hypertension: results of a randomized, double-blind, placebo-controlled trial

    NARCIS (Netherlands)

    Vogt, Liffert; Navis, Gerjan; Koester, Juergen; Manolis, Athanasios J.; Reid, John L.; de Zeeuw, Dick

    2005-01-01

    Objective To examine the effect of telmisartan or hydrochlorothiazide on the control of urinary albumin excretion (UAE) in patients with isolated systolic hypertension (ISH) unselected for albuminuria in a pre-planned substudy of a large, multicentre, double-blind, placebo-controlled, randomized

  18. The angiotensin II receptor antagonist telmisartan reduces urinary albumin excretion in patients with isolated systolic hypertension: results of a randomized, double-blind, placebo-controlled trial

    NARCIS (Netherlands)

    Vogt, Liffert; Navis, Gerjan; Köster, Jürgen; Manolis, Athanasios J.; Reid, John L.; de Zeeuw, Dick

    2005-01-01

    To examine the effect of telmisartan or hydrochlorothiazide on the control of urinary albumin excretion (UAE) in patients with isolated systolic hypertension (ISH) unselected for albuminuria in a pre-planned substudy of a large, multicentre, double-blind, placebo-controlled, randomized study. The

  19. Effect of the BET Protein Inhibitor, RVX-208, on Progression of Coronary Atherosclerosis: Results of the Phase 2b, Randomized, Double-Blind, Multicenter, ASSURE Trial

    NARCIS (Netherlands)

    Nicholls, Stephen J.; Puri, Rishi; Wolski, Kathy; Ballantyne, Christie M.; Barter, Philip J.; Brewer, H. Bryan; Kastelein, John J. P.; Hu, Bo; Uno, Kiyoko; Kataoka, Yu; Herrman, Jean-Paul R.; Merkely, Bela; Borgman, Marilyn; Nissen, Steven E.

    2016-01-01

    Bromodomain and extra-terminal (BET) proteins regulate transcription of lipoprotein and inflammatory factors implicated in atherosclerosis. The impact of BET inhibition on atherosclerosis progression is unknown. ASSURE was a double-blind, randomized, multicenter trial in which 323 patients with

  20. Flexible-dose fesoterodine in elderly adults with overactive bladder: results of the randomized, double-blind, placebo-controlled study of fesoterodine in an aging population trial

    NARCIS (Netherlands)

    Wagg, Adrian; Khullar, Vik; Marschall-Kehrel, Daniela; Michel, Martin C.; Oelke, Matthias; Darekar, Amanda; Bitoun, Caty E.; Weinstein, David; Osterloh, Ian

    2013-01-01

    To assess the efficacy and safety of flexible-dose fesoterodine in elderly adults with overactive bladder (OAB). Twelve-week, randomized, double-blind, placebo-controlled trial. Sixty-one outpatient clinics in Europe, Israel, and Turkey. Seven hundred ninety-four individuals aged 65 and older (47%

  1. 14 CFR 61.16 - Refusal to submit to an alcohol test or to furnish test results.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Refusal to submit to an alcohol test or to... INSTRUCTORS General § 61.16 Refusal to submit to an alcohol test or to furnish test results. A refusal to submit to a test to indicate the percentage by weight of alcohol in the blood, when requested by a law...

  2. Change-readiness of the blind: a hospital based study in a coastal town of South India.

    Science.gov (United States)

    Shetty, Ramya; Kulkarni, Uma D

    2014-01-01

    Blindness is a devastating condition with psychosocial and economic effects. The shortcomings result in a burden to the blind person, the family and society. Rehabilitation of the blind can transform their lives. The aim of this study was to assess the "change-readiness" of the blind to undergo a "change-management". The study was a semi-structured pre-tested questionnaire-based study of 50 blind subjects in a medical college hospital. The blind participants were assessed for depression using the Beck Depression Inventory II, for the perceived effect of blindness on family, social life and occupation. The participants were counseled to undergo psychiatric management, vocational training, use blind aids and learn Braille. The willingness of the participants with reasons was assessed using a verbal analogue scale. Pearson Chi-square test, ANOVA and the t-test were used for statistical analysis. Over two-thirds of the subjects were depressed. Family life, social life and occupation were perceived to be affected by 44%, 66% and 74%, respectively. Change-readiness scores were low for low vision and blind aids, vocational training, psychiatric management, change of job and learning Braille. The low score was due to the associated taboo, dependence, lack of skills, embarrassment, etc., The most valuable feature was the family cohesiveness. The results suggest that there is a need to modify health policy to include blind rehabilitation, to improve visibility of blind rehabilitation centers, to include family members and co-professionals while managing the blind so that we treat the "blind person" and not a "pair of blind eyes".

  3. Assessment of the quality of test results from selected civil engineering material testing laboratories in Tanzania

    CSIR Research Space (South Africa)

    Mbawala, SJ

    2017-12-01

    Full Text Available . Three soil samples commonly found on construction sites in Tanzania were sampled and submitted to the selected five laboratories that were requested to perform the foundation indicator tests (particle size distribution, liquid limit and plastic limit...

  4. Performance test results of mock-up test facility of HTTR hydrogen production system

    International Nuclear Information System (INIS)

    Ohashi, Hirofumi; Inaba, Yoshitomo; Nishihara, Tetsuo

    2004-01-01

    For the purpose to demonstrate effectiveness of high-temperature nuclear heat utilization, Japan Atomic Energy Research Institute has been developing a hydrogen production system and has planned to connect the hydrogen production system to High Temperature Engineering Test Reactor (HTTR). Prior to construction of a HTTR hydrogen production system, a mock-up test facility was constructed to investigate transient behavior of the hydrogen production system and to establish system controllability. The Mock-up test facility with a full-scale reaction tube is an approximately 1/30-scale model of the HTTR hydrogen production system and an electric heater is used as a heat source instead of a reactor. After its construction, a performance test of the test facility was carried out in the same pressure and temperature conditions as those of the HTTR hydrogen production system to investigate its performance such as hydrogen production ability, controllability and so on. It was confirmed that hydrogen was stably produced with a hot helium gas about 120m 3 /h, which satisfy the design value, and thermal disturbance of helium gas during the start-up could be mitigated within the design value by using a steam generator. The mock-up test of the HTTR hydrogen production system using this facility will continue until 2004. (author)

  5. POSTERIOR SEGMENT CAUSES OF BLINDNESS AMONG CHILDREN IN BLIND SCHOOLS

    Directory of Open Access Journals (Sweden)

    Sandhya

    2015-09-01

    Full Text Available BACKGROUND: It is estimated that there are 1.4 million irreversibly blind children in the world out of which 1 million are in Asia alone. India has the highest number of blind children than any other country. Nearly 70% of the childhood blindness is avoidable. There i s paucity of data available on the causes of childhood blindness. This study focuses on the posterior segment causes of blindness among children attending blind schools in 3 adjacent districts of Andhra Pradesh. MATERIAL & METHODS: This is a cross sectiona l study conducted among 204 blind children aged 6 - 16 years age. Detailed eye examination was done by the same investigator to avoid bias. Posterior segment examination was done using a direct and/or indirect ophthalmoscope after dilating pupil wherever nec essary. The standard WHO/PBL for blindness and low vision examination protocol was used to categorize the causes of blindness. A major anatomical site and underlying cause was selected for each child. The study was carried out during July 2014 to June 2015 . The results were analyzed using MS excel software and Epi - info 7 software version statistical software. RESULTS: Majority of the children was found to be aged 13 - 16 years (45.1% and males (63.7%. Family history of blindness was noted in 26.0% and consa nguinity was reported in 29.9% cases. A majority of them were belonged to fulfill WHO grade of blindness (73.0% and in majority of the cases, the onset of blindness was since birth (83.7%. The etiology of blindness was unknown in majority of cases (57.4% while hereditary causes constituted 25.4% cases. Posterior segment causes were responsible in 33.3% cases with retina being the most commonly involved anatomical site (19.1% followed by optic nerve (14.2%. CONCLUSIONS: There is a need for mandatory oph thalmic evaluation, refraction and assessment of low vision prior to admission into blind schools with periodic evaluation every 2 - 3 years

  6. Mulberry-extract improves glucose tolerance and decreases insulin concentrations in normoglycaemic adults: Results of a randomised double-blind placebo-controlled study.

    Directory of Open Access Journals (Sweden)

    Mark Lown

    Full Text Available High sugar and refined carbohydrate intake is associated with weight gain, increased incidence of diabetes and is linked with increased cardiovascular mortality. Reducing the health impact of poor quality carbohydrate intake is a public health priority. Reducose, a proprietary mulberry leaf extract (ME, may reduce blood glucose responses following dietary carbohydrate intake by reducing absorption of glucose from the gut.A double-blind, randomised, repeat measure, phase 2 crossover design was used to study the glycaemic and insulinaemic response to one reference product and three test products at the Functional Food Centre, Oxford Brooks University, UK. Participants; 37 adults aged 19-59 years with a BMI ≥ 20kg/m2 and ≤ 30kg/m2. The objective was to determine the effect of three doses of mulberry-extract (Reducose versus placebo on blood glucose and insulin responses when co-administered with 50g maltodextrin in normoglycaemic healthy adults. We also report the gastrointestinal tolerability of the mulberry extract.Thirty-seven participants completed the study: The difference in the positive Incremental Area Under the Curve (pIAUC (glucose (mmol / L x h for half, normal and double dose ME compared with placebo was -6.1% (-18.2%, 5.9%; p = 0.316, -14.0% (-26.0%, -2.0%; p = 0.022 and -22.0% (-33.9%, -10.0%; p<0.001 respectively. The difference in the pIAUC (insulin (mIU / L x h for half, normal and double dose ME compared with placebo was -9.7% (-25.8%, 6.3%; p = 0.234, -23.8% (-39.9%, -7.8%; p = 0.004 and -24.7% (-40.8%, -8.6%; p = 0.003 respectively. There were no statistically significant differences between any of the 4 groups in the odds of experiencing one or more gastrointestinal symptoms (nausea, abdominal cramping, distension or flatulence.Mulberry leaf extract significantly reduces total blood glucose rise after ingestion of maltodextrin over 120 minutes. The pattern of effect demonstrates a classical dose response curve with

  7. 10 CFR 26.103 - Determining a confirmed positive test result for alcohol.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Determining a confirmed positive test result for alcohol... Specimens for Testing § 26.103 Determining a confirmed positive test result for alcohol. (a) A confirmed positive test result for alcohol must be declared under any of the following conditions: (1) When the...

  8. Experimental Breeder Reactor II inherent shutdown and heat removal tests - test results and analysis

    International Nuclear Information System (INIS)

    Planchon, H.P.; Singer, R.M.; Mohr, D.; Feldman, E.E.; Chang, L.K.; Betten, P.R.

    1985-01-01

    A test program is being conducted to demonstrate that a power producing Liquid Metal Reactor (LMR) can passively remove shutdown heat by natural convection; passively reduce power in response to a loss of reactor flow and passively reduce power in response to a loss of the balance of plant heat sink. Measurements and pretest predictions confirm that natural convection is a reliable, predictable method of shutdown heat removal and suggest that safety-related pumps or pony motors are not necessary for safe, shutdown heat removal in a LMR. Measurements from tests in which reactor flow and heat rejection to the balance of plant were perturbed show that reactivity feedbacks can passively control power and temperature. This data is a basis for additional tests including a complete loss-of-flow without scram and a complete loss of heat sink without scram

  9. A randomized, double-blinded crossover trial testing the benefit of two hydrolysed poultry-based commercial diets for dogs with spontaneous pruritic chicken allergy.

    Science.gov (United States)

    Bizikova, Petra; Olivry, Thierry

    2016-08-01

    Hydrolysed protein diets are used to diagnose and treat dogs with cutaneous adverse food reactions (CAFR). Little is known about what proportion of dogs hypersensitive to the native protein would react to its hydrolysed form. To determine the clinical allergenicity of hydrolysed poultry feather (RCU) and chicken liver diets (HZD) in dogs with chicken induced CAFR. In this randomized, double-blinded, crossover trial, ten dogs with chicken induced CAFR were selected after a positive oral challenge to chicken meat and a negative one to corn. Test diets were fed for 14 days separated by a 14 day wash-out period. Owners rated pruritus daily with a Visual Analog Scale (PVAS). The challenge was ended if a flare in pruritus occurred (i.e. PVAS ≥5/10). The median PVAS scores before feeding RCU and HZD were 0.9 and 1.7, respectively (Wilcoxon signed rank test, P = 0.46). Pruritus scores increased significantly after feeding HZD (Friedman's test, P dogs fed RCU, but four dogs fed HZD (40%), were withdrawn after a flare in pruritus developed (Fisher's test, P = 0.04). The maximal PVAS score was significantly higher after HZD (median: 4.7) compared to RCU (2.5) (Wilcoxon signed rank test, P = 0.01). One dog in each group was withdrawn due to diarrhoea. The hydrolysed poultry feather diet did not induce pruritus flares in dogs allergic to chicken in contrast to the hydrolysed chicken liver diet that led to pruritus flares in 40% of these dogs. © 2016 ESVD and ACVD.

  10. QADATA user's manual; an interactive computer program for the retrieval and analysis of the results from the external blind sample quality- assurance project of the U.S. Geological Survey

    Science.gov (United States)

    Lucey, K.J.

    1990-01-01

    The U.S. Geological Survey conducts an external blind sample quality assurance project for its National Water Quality Laboratory in Denver, Colorado, based on the analysis of reference water samples. Reference samples containing selected inorganic and nutrient constituents are disguised as environmental samples at the Survey 's office in Ocala, Florida, and are sent periodically through other Survey offices to the laboratory. The results of this blind sample project indicate the quality of analytical data produced by the laboratory. This report provides instructions on the use of QADATA, an interactive, menu-driven program that allows users to retrieve the results of the blind sample quality- assurance project. The QADATA program, which is available on the U.S. Geological Survey 's national computer network, accesses a blind sample data base that contains more than 50,000 determinations from the last five water years for approximately 40 constituents at various concentrations. The data can be retrieved from the database for any user- defined time period and for any or all available constituents. After the user defines the retrieval, the program prepares statistical tables, control charts, and precision plots and generates a report which can be transferred to the user 's office through the computer network. A discussion of the interpretation of the program output is also included. This quality assurance information will permit users to document the quality of the analytical results received from the laboratory. The blind sample data is entered into the database within weeks after being produced by the laboratory and can be retrieved to meet the needs of specific projects or programs. (USGS)

  11. Crossmodal recruitment of the ventral visual stream in congenital blindness

    DEFF Research Database (Denmark)

    Ptito, Maurice; Matteau, Isabelle; Zhi Wang, Arthur

    2012-01-01

    We used functional MRI (fMRI) to test the hypothesis that blind subjects recruit the ventral visual stream during nonhaptic tactile-form recognition. Congenitally blind and blindfolded sighted control subjects were scanned after they had been trained during four consecutive days to perform...... a tactile-form recognition task with the tongue display unit (TDU). Both groups learned the task at the same rate. In line with our hypothesis, the fMRI data showed that during nonhaptic shape recognition, blind subjects activated large portions of the ventral visual stream, including the cuneus, precuneus......, inferotemporal (IT), cortex, lateral occipital tactile vision area (LOtv), and fusiform gyrus. Control subjects activated area LOtv and precuneus but not cuneus, IT and fusiform gyrus. These results indicate that congenitally blind subjects recruit key regions in the ventral visual pathway during nonhaptic...

  12. Characterization of a Test for Invasive Breast Cancer Using X-ray Diffraction of Hair - Results of a Clinical Trial

    Directory of Open Access Journals (Sweden)

    Gary L. Corino

    2009-11-01

    Full Text Available Objective: To assess the performance of a test for breast cancer utilizing synchrotron x-ray diffraction analysis of scalp hair from women undergoing diagnostic radiology assessment. Design and Setting: A double-blinded clinical trial of women who attended diagnostic radiology clinics in Australia. Patients: 1796 women referred for diagnostic radiology, with no previous history of cancer. Main Outcome Measures: Sensitivity, specificity and accuracy of the hair test analysis compared to the gold standard of imaging followed by biopsy where indicated. Results: The hair-based assay had an overall accuracy of >77% and a negative predictive value of 99%. For all women, the sensitivity of both mammography and x-ray diffraction alone was 64%, but when used together the sensitivity rose to 86%. The sensitivity of the hair test for women under the age of 70 was 74%. Conclusion: In this large population trial the association between the presence of breast cancer and an altered hair fibre X-ray diffraction pattern previously reported has been confirmed. It appears that mammography and X-ray diffraction of hair detect different populations of breast cancers, and are synergistic when used together.

  13. Building Energy Simulation Test for Existing Homes (BESTEST-EX): Instructions for Implementing the Test Procedure, Calibration Test Reference Results, and Example Acceptance-Range Criteria

    Energy Technology Data Exchange (ETDEWEB)

    Judkoff, R.; Polly, B.; Bianchi, M.; Neymark, J.; Kennedy, M.

    2011-08-01

    This publication summarizes building energy simulation test for existing homes (BESTEST-EX): instructions for implementing the test procedure, calibration tests reference results, and example acceptance-range criteria.

  14. Efficacy of Wobe-Mugos {sup registered} E for reduction of oral mucositis after radiotherapy. Results of a prospective, randomized, placebo-controlled, triple-blind phase III multicenter study

    Energy Technology Data Exchange (ETDEWEB)

    Doerr, W.; Herrmann, T. [Univ. of Technology, Dresden (Germany). Dept. of Radiotherapy and Radiooncology, Medical Faculty Carl Gustav Carus

    2007-03-15

    Purpose: To investigate the efficacy and safety of Wobe-Mugos {sup registered} E (proteolytic enzymes) for amelioration of early side effects of radiotherapy for head-and-neck tumors, particularly oral mucositis. Patients and Methods: The study was a prospective, randomized, multicenter, placebo-controlled, triple-blind phase III study with parallel groups. 69 patients with carcinomas of the oropharynx or the oral cavity were enrolled between 1996 and 2000 in five centers; 54 of these were recruited in Dresden. Of the 69 patients, 61 (Dresden: 46) were available for analysis. The proteolytic enzymes tested (Wobe-Mugos {sup registered} E) comprised papain 100 mg, trypsin 40 mg, and chymotrypsin 40 mg. Results: Wobe-Mugos {sup registered} E was well tolerated. For the maximum mucositis scores, no statistically significant differences were found between the placebo and the verum group. The average mucositis score over weeks 1-6 revealed a significant difference in favor of the placebo arm, based on an earlier onset of mucositis in the Wobe-Mugos {sup registered} E group. Conclusion: The present study failed to demonstrate any effect of treatment with Wobe-Mugos {sup registered} E on radiotherapy side effects in patients treated for head-and-neck tumors. In particular, there was no beneficial effect on radiation-induced early oral mucositis. (orig.)

  15. Efficacy of Wobe-Mugos registered E for reduction of oral mucositis after radiotherapy. Results of a prospective, randomized, placebo-controlled, triple-blind phase III multicenter study

    International Nuclear Information System (INIS)

    Doerr, W.; Herrmann, T.

    2007-01-01

    Purpose: To investigate the efficacy and safety of Wobe-Mugos registered E (proteolytic enzymes) for amelioration of early side effects of radiotherapy for head-and-neck tumors, particularly oral mucositis. Patients and Methods: The study was a prospective, randomized, multicenter, placebo-controlled, triple-blind phase III study with parallel groups. 69 patients with carcinomas of the oropharynx or the oral cavity were enrolled between 1996 and 2000 in five centers; 54 of these were recruited in Dresden. Of the 69 patients, 61 (Dresden: 46) were available for analysis. The proteolytic enzymes tested (Wobe-Mugos registered E) comprised papain 100 mg, trypsin 40 mg, and chymotrypsin 40 mg. Results: Wobe-Mugos registered E was well tolerated. For the maximum mucositis scores, no statistically significant differences were found between the placebo and the verum group. The average mucositis score over weeks 1-6 revealed a significant difference in favor of the placebo arm, based on an earlier onset of mucositis in the Wobe-Mugos registered E group. Conclusion: The present study failed to demonstrate any effect of treatment with Wobe-Mugos registered E on radiotherapy side effects in patients treated for head-and-neck tumors. In particular, there was no beneficial effect on radiation-induced early oral mucositis. (orig.)

  16. The Efficacy and Safety of Add-on Ginko TD (Ginkgo Biloba Treatment for PTSD: Results of a 12-Week Double-Blind Placebo-Controlled Study

    Directory of Open Access Journals (Sweden)

    Laleh Koohi Habibi

    2007-06-01

    Full Text Available "nObjective: Exposure to traumatic stressors lead to activation of arousal responses mediated by serotonergic and noradrenergic systems and it may cause a change in numerous neurotransmitters and neuroendocrine systems. There is ample experimental and clinical evidence to suggest that Ginkgo biloba extract is neuroprotective and has antioxidant properties and can restore stress-induced elevation in brain levels of catecholamines, 5-HT and plasma corticosterone to normal level. "nMethod: In a 12-week, double-blind, placebo-controlled study, the efficacy and safety of adding-on a fixed-dose (200mg of Ginkgo TD to the previous treatment regime of adults with PTSD were examined. Subjects were forty male and female outpatients from a public-owned psychiatric clinic who met criteria for PTSD seven month after a 6.3 Richter earthquake in Bam city on December 26, 2003. The changes in five symptom domains including posttraumatic stress, anxiety and affective symptoms, general health and subjective stress after trauma were ssessed at weeks 0, 12 and 16 to examine effectiveness of the added-on Ginkgo TD and stability of its effects. "nResults: Ginkgo TD was associated with a significantly greater improvement than placebo in PTSD patients as measured by five symptom domain scales including: GHQ-28; Watson PTSD Scale; HAM-D; HAM-A and IES (p= 0.02, 0.01, 0.001, 0.01, 0.02 respectively Four weeks after the discontinuation of intervention, no significant difference was determined between the two groups in the five outcome measures (p= 0.005, 0.01, 0.004, 0.005, 0.01 respectively. No significant difference was observed between the two groups in terms of side effects. "nConclusions: We found Ginkgo TD to be superior to placebo as an adding-on in the treatment of PTSD. Although we did not examine the comparative efficacy of Ginkgo TD on the three main elements of PTSD, beneficial effects both on specific PTSD symptomatology and general conditions including

  17. A pilot study on efficacy treatment of acne vulgaris using a new method: results of a randomized double-blind trial with Acne Dressing.

    Science.gov (United States)

    Chao, Chao-Ming; Lai, Wei-Yu; Wu, Bai-Yao; Chang, Hung-Chia; Huang, Wei-Shuan; Chen, Yu-Fei

    2006-01-01

    For many years the positive effect of hydrocolloid dressings on skin-related conditions attracted the attention of the medical scientific community. The use of Acne Dressing, a tape of hydrocolloid dressing, for the treatment of acne has not been reported previously. The aim of this study was to evaluate the clinical efficacy and beneficial effect of Acne Dressing on the marker for sebum output evaluations. We also determined the cosmetic outcome of this application during the treatment of acne and whether the material could prevent hand touching and UVB light from reaching the skin surface. The objective of this study was to assess improvement in acne vulgaris and tolerability during one week of short contact treatment with Acne Dressing compared to skin tapes. Efficacy data specific to treatment of acne vulgaris with Acne Dressing (3M Health Care) from a double-blind, randomized, skin types-controlled study is reported. A total of 20 patients with mild-to-moderate acne vulgaris applied the skin tapes or Acne Dressing every two days for up to one week. Twenty patients were enrolled in this study: ten patients received Acne Dressing and ten patients received skin tapes. Both groups showed decreases from baseline to the end of treatment in the mean of the overall severity scale (decrease of 1.37 from 1.8 to 0.43 with Acne Dressing and 0.28 from 1.08 to 0.8 with skin tapes). A statistically significant greater reduction was observed over a period of three to seven days in the overall severity of acne and inflammation in the Acne Dressing group compared with the mono-therapy (skin tapes) group. Similarly, Acne Dressing resulted in a significantly greater improvement in the redness, oiliness, dark pigmentation, and sebum casual level at days 3, 5, and 7. The ratio of transmission of UVB light with Acne Dressing was 7.4%, and 38% with skin tapes, which shows less UVB light reaching the skin surface with the Acne Dressing. No significant adverse events were identified in

  18. Muscle uncoupling protein 3 expression is unchanged by chronic ephedrine/caffeine treatment: results of a double blind, randomised clinical trial in morbidly obese females.

    Directory of Open Access Journals (Sweden)

    Renata Bracale

    Full Text Available Ephedrine/caffeine combination (EC has been shown to induce a small-to-moderate weight loss in obese patients. Several mechanisms have been proposed, among which an increased thermogenic capacity of skeletal muscle consequent to the EC-induced up-regulation of uncoupling protein 3 (UCP3 gene expression. We did a parallel group double-blind, placebo-controlled, 4-week trial to investigate this hypothesis. Thirteen morbidly obese women (25-52 years of age, body-mass index 48.0±4.0 kg/m2, range 41.1-57.6 were randomly assigned to EC (200/20 mg, n = 6 or to placebo (n = 7 administered three times a day orally, before undergoing bariatric surgery. All individuals had an energy-deficit diet equal to about 70% of resting metabolic rate (RMR diet (mean 5769±1105 kJ/day. The RMR analysed by intention to treat and the UCP3 (long and short isoform mRNA levels in rectus abdominis were the primary outcomes. Body weight, plasma levels of adrenaline, noradrenaline, triglycerides, free fatty acids, glycerol, TSH, fT4, and fT3 were assessed, as well as fasting glucose, insulin and HOMA index, at baseline and at the end of treatments. Body weight loss was evident in both groups when compared to baseline values (overall -5.2±3.2%, p<0.0001 without significant differences between the treated groups. EC treatment increased the RMR (+9.2±6.8%, p = 0.020, differently from placebo which was linked to a reduction of RMR (-7.6±6.5%, p = 0.029. No significant differences were seen in other metabolic parameters. Notably, no changes of either UCP3 short or UCP3 long isoform mRNA levels were evident between EC and placebo group. Our study provides evidence that 4-week EC administration resulted in a pronounced thermogenic effect not related to muscle UCP3 gene expression and weight loss in morbidly obese females under controlled conditions.ClinicalTrials.gov NCT02048215.

  19. Women's Experience with Non-Invasive Prenatal Testing and Emotional Well-being and Satisfaction after Test-Results

    NARCIS (Netherlands)

    Schendel, R.V. van; Page-Christiaens, G.; Beulen, L.; Bilardo, C.M.; Boer, M.A. de; Coumans, A.B.C.; Faas, B.H.W.; Langen, I.M. van; Lichtenbelt, K.D.; Maarle, M.C. van; Macville, M.V.E.; Oepkes, D.; Pajkrt, E.; Henneman, L.

    2017-01-01

    Increasingly, high-risk pregnant women opt for non-invasive prenatal testing (NIPT) instead of invasive diagnostic testing. Since NIPT is less accurate than invasive testing, a normal NIPT result might leave women less reassured. A questionnaire study was performed among pregnant women with elevated

  20. Trends in Pap Test Practices and Results: An 11-Year Review of the Annual ACHA Pap Test and STI Survey

    Science.gov (United States)

    Eastman-Mueller, Heather P.; Oswalt, Sara B.

    2017-01-01

    Objective: To conduct a trend analysis of Pap test practices, Pap test results and related women's services and guidelines of college health centers. Participants: College health centers who participated in the annual ACHA Pap Test and STI (sexually transmitted infection) Survey years 2004-2014 (n ranged from 127 to 181 depending on year).…

  1. 49 CFR 40.255 - What happens next after the alcohol confirmation test result?

    Science.gov (United States)

    2010-10-01

    ... FOR TRANSPORTATION WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Alcohol Confirmation Tests § 40.255 What happens next after the alcohol confirmation test result? (a) After the EBT has printed the result of an alcohol confirmation test, you must, as the BAT, take the following additional steps: (1) Sign...

  2. Final report of the Buffer Mass Test. Volume II: test results

    International Nuclear Information System (INIS)

    Pusch, R.; Boerjesson, L.; Ramqvist, G.

    1985-08-01

    The evaluation of the Buffer Mass Test mainly concerned the heating of the bentonite/rock system that simulated hot canisters in deposition holes, the swelling and swelling pressure of the expanding bentonite in the heater holes, and the water uptake of the bentonite in the holes as well as in the tunnel backfill. These processes had been predicted on the basis of laboratory-derived data and FEM calculations with due consideration of the actual geometry. The recorded temperatures of the bentonite and surrounding rock were found to be below the maximum temperature that had been set, but higher than the expected values in the initial period of testing. The heater surface temperatures dropped in the course of the tests due to the uptake of water from the rock even in the driest hole which was located in almost fracture-free rock. The water uptake in the highly compacted bentonite in the heater holes was manifested by a successively increased swelling pressure at the bentonite/rock interface. It was rather uniformly distributed over this interface and reached a maximum value of about 10 MPa. The water content determination confirmed that water had been absorbed by the bentonite from the rock even in the driest holes where the counteracting thermal gradient was rather high. In the wettest holes the saturation became almost complete and a high degree of saturation was also observed in the tunnel backfill. Both in the heater holes and the tunnel, the moistening was found to be very uniform along the periphery, which is at least partly explained by the self-sealing ability of bentonite buffer materials. A general conclusion is that the involved physical processes are well understood and that the ultimate physical state of the buffer materials under repository conditions can be safely predicted. With 15 refs. (Author)

  3. Outcome of transcutaneous electrical nerve stimulation in chronic pain: short-term results of a double-blind, randomised, placebo-controlled trial.

    NARCIS (Netherlands)

    Oosterhof, J.; Boo, T.M. de; Oostendorp, R.A.B.; Wilder-Smith, O.H.G.; Crul, B.J.P.

    2006-01-01

    The aim of this study was to test the efficacy of shortterm transcutaneous electrical nerve stimulation (TENS) treatment in chronic pain with respect to pain intensity and patients' satisfaction with treatment results. We therefore performed a randomised controlled trial comparing TENS and sham

  4. Summary of microsatellite instability test results from laboratories participating in proficiency surveys: proficiency survey results from 2005 to 2012.

    Science.gov (United States)

    Boyle, Theresa A; Bridge, Julia A; Sabatini, Linda M; Nowak, Jan A; Vasalos, Patricia; Jennings, Lawrence J; Halling, Kevin C

    2014-03-01

    The College of American Pathologists surveys are the largest laboratory peer comparison programs in the world. These programs allow laboratories to regularly evaluate their performance and improve the accuracy of the patient test results they provide. Proficiency testing is offered twice a year to laboratories performing microsatellite instability testing. These surveys are designed to emulate clinical practice, and some surveys have more challenging cases to encourage the refinement of laboratory practices. This report summarizes the results and trends in microsatellite instability proficiency testing from participating laboratories from the inception of the program in 2005 through 2012. We compiled and analyzed data for 16 surveys of microsatellite instability proficiency testing during 2005 to 2012. The number of laboratories participating in the microsatellite instability survey has more than doubled from 42 to 104 during the 8 years analyzed. An average of 95.4% of the laboratories correctly classified each of the survey test samples from the 2005A through 2012B proficiency challenges. In the 2011B survey, a lower percentage of laboratories (78.4%) correctly classified the specimen, possibly because of overlooking subtle changes of microsatellite instability and/or failing to enrich the tumor content of the specimen to meet the limit of detection of their assay. In general, laboratories performed well in microsatellite instability testing. This testing will continue to be important in screening patients with colorectal and other cancers for Lynch syndrome and guiding the management of patients with sporadic colorectal cancer.

  5. An Overwhelming Desire to Be Blind: Similarities and Differences between Body Integrity Identity Disorder and the Wish for Blindness

    Directory of Open Access Journals (Sweden)

    Katja Gutschke

    2017-03-01

    Full Text Available Background: The urge to be permanently blind is an extremely rare mental health disturbance. The underlying cause of this desire has not been determined yet, and it is uncertain whether the wish for blindness is a condition that can be included in the context of body integrity identity disorder, a condition where people feel an overwhelming need to be disabled, in many cases by amputation of a limb or through paralysis. Objective: The aim of this study is to test the hypothesis that people with a desire for blindness suffer from a greater degree of visual stress in daily activities than people in a healthy visual control group. Method: We created a Likert scale questionnaire to measure visual stress, covering a wide range of everyday situations. The wish for blindness is extremely rare and worldwide only 5 people with an urge to be blind were found to participate in the study (4 female, 1 male. In addition, a control group of 35 (28 female, 7 male visually healthy people was investigated. Questions addressing issues that may be experienced by participants with a desire to be blind were integrated into the questionnaire. Results: The hypothesis that people with a desire for blindness suffer from a significantly higher visual overload in activities of daily living than visually healthy subjects was confirmed; the significance of visual stress between these groups was p < 0.01. In addition, an interview with the 5 affected participants supported the causal role of visual overload. Conclusions: The desire for blindness seems to originate from visual overload caused by either ophthalmologic or organic brain disturbances. In addition, psychological reasons such as certain personal character traits may play an active role in developing, maintaining, and reinforcing one’s desire to be blind.

  6. Recommendations for reporting results of diagnostic genetic testing (biochemical, cytogenetic and molecular genetic)

    NARCIS (Netherlands)

    Claustres, Mireille; Kozich, Viktor; Dequeker, Els; Fowler, Brain; Hehir-Kwa, Jayne Y.; Miller, Konstantin; Oosterwijk, Cor; Peterlin, Borut; van Ravenswaaij-Arts, Conny; Zimmermann, Uwe; Zuffardi, Orsetta; Hastings, Ros J.; Barton, David E.

    Genetic test results can have considerable importance for patients, their parents and more remote family members. Clinical therapy and surveillance, reproductive decisions and genetic diagnostics in family members, including prenatal diagnosis, are based on these results. The genetic test report

  7. Novel, sensitive and low-cost diagnostic tests for 'river blindness'--detection of specific antigens in tears, urine and dermal fluid.

    Science.gov (United States)

    Ngu, J L; Nkenfou, C; Capuli, E; McMoli, T E; Perler, F; Mbwagbor, J; Tume, C; Nlatte, O B; Donfack, J; Asonganyi, T

    1998-05-01

    Sensitive, specific and low-cost diagnostic tests for onchocerciasis are indispensable for monitoring the efficacy of control programs, as well as for preventing blindness (when the tests are combined with efficacious chemotherapy. Three new tests to detect Onchocerca-specific antigens in tears, dermal fluid and urine employ antibodies to O. volvulus-specific recombinant proteins, Oncho-C27 and OvD3B, encoded by genes within the immunodominant Onchocerca OV 33-3 gene family, and expressed in yeast and in E. coli, respectively. In these assays, Onchocerca-specific antigens in test samples are bound onto a solid surface and revealed using appropriate enzyme-labelled antibodies. Proteins in the samples are first transferred to Hybond-N + membrane disks or nitrocellulose paper using either a transblot or a dotblot machine, and then reacted with specific O. volvulus antibodies. Bound antibodies are revealed with species-specific peroxidase-labelled antibodies and peroxidase substrate. Positive tests give a brown colour. In one of the two assays developed to detect Onchocerca antigens in tears, the sensitivity was enhanced by first adsorbing the specific antibodies onto the membrane surface in order to immobilize and concentrate the Onchocerca-specific antigen molecules on the membrane. The specificity of the recombinant proteins for Onchocerca volvulus had been verified by ELISA, classical Western blot and modified DSIA. The tests are a dipstick immunobinding assay for ocular microfilariae (DSIA), a transblot immunobinding assay for the detection of skin microfilariae (TADA) and a dot-blot immunobinding assay for detecting urinary microfilariae and their antigens (DIA). Their specificity and sensitivity were evaluated in the field on 110 subjects with proven ocular microfilariae, 130 subjects with clinical and parasitological evidence of onchocerciasis, 25 subjects infected with other helminths and 120 normal controls. The minimal detection limits of Oncho-C27 protein

  8. Vision after 53 years of blindness.

    Science.gov (United States)

    Sikl, Radovan; Simecček, Michal; Porubanová-Norquist, Michaela; Bezdíček, Ondřej; Kremláček, Jan; Stodůlka, Pavel; Fine, Ione; Ostrovsky, Yuri

    2013-01-01

    Several studies have shown that visual recovery after blindness that occurs early in life is never complete. The current study investigated whether an extremely long period of blindness might also cause a permanent impairment of visual performance, even in a case of adult-onset blindness. We examined KP, a 71-year-old man who underwent a successful sight-restoring operation after 53 years of blindness. A set of psychophysical tests designed to assess KP's face perception, object recognition, and visual space perception abilities were conducted six months and eight months after the surgery. The results demonstrate that regardless of a lengthy period of normal vision and rich pre-accident perceptual experience, KP did not fully integrate this experience, and his visual performance remained greatly compromised. This was particularly evident when the tasks targeted finer levels of perceptual processing. In addition to the decreased robustness of his memory representations, which was hypothesized as the main factor determining visual impairment, other factors that may have affected KP's performance were considered, including compromised visual functions, problems with perceptual organization, deficits in the simultaneous processing of visual information, and reduced cognitive abilities.

  9. Vision after 53 Years of Blindness

    Directory of Open Access Journals (Sweden)

    Radovan Šikl

    2013-12-01

    Full Text Available Several studies have shown that visual recovery after blindness that occurs early in life is never complete. The current study investigated whether an extremely long period of blindness might also cause a permanent impairment of visual performance, even in a case of adult-onset blindness. We examined KP, a 71-year-old man who underwent a successful sight-restoring operation after 53 years of blindness. A set of psychophysical tests designed to assess KP's face perception, object recognition, and visual space perception abilities were conducted six months and eight months after the surgery. The results demonstrate that regardless of a lengthy period of normal vision and rich pre-accident perceptual experience, KP did not fully integrate this experience, and his visual performance remained greatly compromised. This was particularly evident when the tasks targeted finer levels of perceptual processing. In addition to the decreased robustness of his memory representations, which was hypothesized as the main factor determining visual impairment, other factors that may have affected KP's performance were considered, including compromised visual functions, problems with perceptual organization, deficits in the simultaneous processing of visual information, and reduced cognitive abilities.

  10. Experimental results from containment piping bellows subjected to severe accident conditions: Results from bellows tested in corroded conditions. Volume 2

    International Nuclear Information System (INIS)

    Lambert, L.D.; Parks, M.B.

    1995-10-01

    Bellows are an integral part of the containment pressure boundary in nuclear power plants. They are used at piping penetrations to allow relative movement between piping and the containment wall, while minimizing the load imposed on the piping and wall. Piping bellows are primarily used in steel containments; however, they have received limited use in some concrete (reinforced and prestressed) containments. In a severe accident they may be subjected to pressure and temperature conditions that exceed the design values, along with a combination of axial and lateral deflections. A test program to determine the leak-tight capacity of containment penetration bellows is being conducted at Sandia National Laboratories under the sponsorship of the US Nuclear Regulatory Commission. Several different bellows geometries, representative of actual containment bellows, have been subjected to extreme deflections along with pressure and temperature loads. The bellows geometries and loading conditions are described along with the testing apparatus and procedures. A total of nineteen bellows have been tested. Thirteen bellows were tested in ''like-new'' condition (results reported in Volume 1), and six were tested in a corroded condition. The tests showed that bellows in ''like-new'' condition are capable of withstanding relatively large deformations, up to, or near, the point of full compression or elongation, before developing leakage, while those in a corroded condition did not perform as well, depending on the amount of corrosion. The corroded bellows test program and results are presented in this report

  11. How do people respond to self-test results? A cross-sectional survey

    Directory of Open Access Journals (Sweden)

    de Vries Nanne K

    2010-10-01

    Full Text Available Abstract Background Self-tests, tests on medical conditions that can be performed by consumers without consulting a doctor first, are frequently used. Nevertheless, there are concerns about the safety of self-testing, as it may delay diagnosis and appropriate treatment in the case of inappropriate use of the test, or false-negative results. It is unclear whether self-tests stimulate appropriate follow-up behaviour. Our aim was to examine the frequency of self-test use, consumers' response to self-test results in terms of their confidence in the result, reassurance by the test result, and follow-up behaviour. Methods A two step cross-sectional survey was designed. A random sample of 6700 Internet users in an existing Internet panel received an online questionnaire on the use of self-tests. Self-tests were defined as tests on body materials, initiated by consumers with the aim to diagnose a disease or risk factor. A second questionnaire on consumers' response to self-test results was sent to the respondents that were identified as a self-tester in the first questionnaire (n = 703. Results 18.1% (799/4416 of the respondents had ever performed a self-test, the most frequently used tests being those for diabetes (5.3%, kidney disease (4.9%, cholesterol (4.5%, urinary tract infection (1.9% and HIV/AIDS and Chlamydia (both 1.6%. A total of 78.1% of the testers with a normal test result and 81.4% of those with an abnormal result reported confidence in this result. Almost all (95.6% of the testers with a normal result felt reassured. After a normal result, 78.1% did not take any further action and 5.8% consulted a doctor. The corresponding figures after an abnormal test result were 9.3% and 72.2%, respectively. Conclusions Respondents who had performed a self-test seemed to base their follow-up behaviour on the result of the test. They had confidence in the test result, and were often reassured by a normal result. After an abnormal result, most self

  12. A yeast fermentate improves gastrointestinal discomfort and constipation by modulation of the gut microbiome: results from a randomized double-blind placebo-controlled pilot trial.

    Science.gov (United States)

    Pinheiro, Iris; Robinson, Larry; Verhelst, An; Marzorati, Massimo; Winkens, Björn; den Abbeele, Pieter Van; Possemiers, Sam

    2017-09-04

    Constipation and symptoms of gastrointestinal discomfort such as bloating are common among otherwise healthy individuals, but with significant impact on quality of life. Despite the recognized contribution of the gut microbiome to this pathology, little is known about which group(s) of microorganism(s) are playing a role. A previous study performed in vitro suggests that EpiCor® fermentate has prebiotic-like properties, being able to favorably modulate the composition of the gut microbiome. Therefore, the aim of this study was to investigate the effects of EpiCor fermentate in a population with symptoms of gastrointestinal discomfort and reduced bowel movements and to evaluate its effect at the level of the gut microbiome. This pilot study was performed according to a randomized, double-blind, placebo-controlled parallel design. Eighty subjects with symptoms of gastrointestinal discomfort and constipation were allocated to one of two trial arms (placebo or EpiCor fermentate). Randomization was done in a stratified manner according to symptom severity, resulting in two subgroups of patients: severe and moderate. Daily records of gastrointestinal symptoms were assessed on a 5-point scale, and also stool frequency and consistency were documented during a 2-week run-in and a 6-week intervention phases. Averages over two-week intervals were calculated. Constipation-associated quality of life and general perceived stress were assessed at baseline and after 3 and 6 weeks of intervention. Fecal samples were also collected at these same time points. EpiCor fermentate led to a significant improvement of symptoms such as bloating/distension (p = 0.033 and p = 0.024 after 2 and 4 weeks of intervention, respectively), feeling of fullness (p = 0.004 and p = 0.023 after 2 and 4 weeks of intervention, respectively) and general daily scores (p = 0.046 after 2 weeks of intervention) in the moderate subgroup. A significant improvement in stool consistency was observed

  13. Effects of carvedilol in heart failure due to dilated cardiomyopathy. Results of a double-blind randomized placebo-controlled study (CARIBE study)

    OpenAIRE

    Chizzola,Paulo Roberto; Freitas,Humberto Felício Gonçalves; Caldas,Márcia Azevedo; Costa,Joicely Melo da; Meneghetti,Cláudio; Marinho,Norma Vasconcelos Saldanha; Mansur,Alfredo José; Ramires,José Antonio Franchini; Bocchi,Edimar Alcides

    2000-01-01

    OBJECTIVE: To assess the effects of carvedilol in patients with idiopathic dilated cardiomyopathy. METHODS: In a double-blind randomized placebo-controlled study, 30 patients (7 women) with functional class II and III heart failure were assessed. Their ages ranged from 28 to 66 years (mean of 43±9 years), and their left ventricular ejection fraction varied from 8% to 35%. Carvedilol was added to the usual therapy of 20 patients; placebo was added to the usual therapy of 10 patients. The initi...

  14. [Blindness and visual rehabilitation].

    Science.gov (United States)

    Matonti, F; Roux, S; Denis, D; Picaud, S; Chavane, F

    2015-02-01

    Blindness and visual impairment are a major public health problem all over the world and in all societies. A large amount of basic science and clinical research aims to rehabilitate patients and help them become more independent. Various methods are explored from cell and molecular therapy to prosthetic interfaces. We review the various treatment alternatives, describing their results and their limitations. Copyright © 2014 Elsevier Masson SAS. All rights reserved.

  15. Is the quality of sushi ruined by freezing raw fish and squid? A randomized double-blind trial with sensory evaluation using discrimination testing.

    Science.gov (United States)

    Iwata, Kentaro; Fukuchi, Takahiko; Yoshimura, Kenichi

    2015-05-01

    Sushi is a traditional Japanese cuisine enjoyed worldwide. However, using raw fish to make sushi may pose risk of certain parasitic infections, such as anisakidosis, which is most reported in Japan. This risk of infection can be eliminated by freezing fish; however, Japanese people are hesitant to freeze fish because it is believed that freezing ruins sushi's taste. A randomized double-blind trial with discrimination testing was conducted to examine the ability of Japanese individuals to distinguish between frozen and unfrozen sushi. A pair of mackerel and squid sushi, one once frozen and the other not, was provided to the participants, and they were asked to answer which one tasted better. Among 120 rounds of discrimination testing involving the consumption of 240 pieces of mackerel sushi, unfrozen sushi was believed to taste better in 42.5% (51 dishes) of cases, frozen sushi was thought to taste better in 49.2% (59 dishes), and the participants felt the taste was the same in 8.3% (10 dishes). The odds ratio for selecting unfrozen sushi as "tastes better" over frozen sushi was 0.86 (95% confidence interval [CI], .59-1.26; P = .45). For squid, unfrozen sushi was believed to be superior 48.3% of the time (58 dishes), and frozen sushi, 35.0% of the time (42 dishes). They were felt to be the same in 16.7% (20 dishes) (odds ratio, 1.38; 95% CI, .93-2.05; P = .11). Freezing raw fish did not ruin sushi's taste. These findings may encourage the practice of freezing fish before using it in sushi, helping to decrease the incidence of anisakidosis. © The Author 2015. Published by Oxford University Press on behalf of the Infectious Diseases Society of America.

  16. 40 CFR 90.709 - Calculation and reporting of test results.

    Science.gov (United States)

    2010-07-01

    ... procedures for the engine family tested have been made during this production line testing program that affect engines from the production line. All data and information reported herein is, to the best of... Manufacturer Production Line Testing Program § 90.709 Calculation and reporting of test results. (a) Initial...

  17. Results from Second Round of Remediated Nitrate Salt Surrogate Formulation and Testing

    Energy Technology Data Exchange (ETDEWEB)

    Brown, Geoffrey Wayne [Los Alamos National Laboratory; Leonard, Philip [Los Alamos National Laboratory; Hartline, Ernest Leon [Los Alamos National Laboratory; Tian, Hongzhao [Los Alamos National Laboratory

    2016-04-04

    High Explosives and Technology (M-7) completed the second round of formulation and testing of Remediated Nitrate Salt (RNS) surrogates on March 17, 2016. This report summarizes the results of the work and also includes additional documentation required under test plan PLAN-TA9-2443 Rev B, "Remediated Nitrate Salt (RNS) Surrogate Formulation and Testing Standard Procedure", released February 16, 2016. All formulation and testing was carried out according to PLAN-TA9-2443 Rev B. Results from the first round of formulation and testing were documented in memorandum M7-16-6042, "Results from First Round of Remediated Nitrate Salt Surrogate Formulation and Testing."

  18. Radioprotection of salivary glands by amifostine in high-dose radioiodine treatment. Results of a double-blinded, placebo-controlled study in patients with differentiated thyroid cancer

    Energy Technology Data Exchange (ETDEWEB)

    Bohuslavizki, K.H.; Klutmann, S.; Kroeger, S.; Buchert, R.; Bleckmann, C.; Mester, J.; Clausen, M. [Universitaetskrankenhaus Eppendorf, Hamburg (Germany). Abt. Nuklearmedizin; Brenner, W.; Henze, E. [Kiel Univ. (Germany). Klinik fuer Nuklearmedizin

    1999-11-01

    Background and purpose: Parenchymal impairment of salivary glands following high-dose radioiodine treatment is a well-known side effect in general caused by free radicals. Therefore, the radioprotective effect of the radical scavenger amifostine was evaluated prospectively in patients receiving high-dose radioiodine treatment. Patients and methods: Parenchymal function was assessed by quantitative salivary gland scintigraphy performed in 50 patients with differentiated thyroid cancer prior to and 3 months after high-dose radioiodine treatment with either 3 GBq {sup 131}I (n=21) or 6 BGq {sup 131}I (n=29) in a double-blinded, placebo-controlled study. Twenty-five patients treated with 500 mg/m{sup 2} amifostine intravenously prior to high-dose radioiodine treatment were compared to 25 control patients receiving physiological saline solution. Xerostomia was graded according to WHO-criteria. Results: In 25 control patients high-dose radioiodine treatment significantly (p<0.001) reduced parenchymal function of parotid and submandibular glands by 40.2{+-}14.1% and 39.9{+-}15.3%, respectively. Nine out of these 25 patients developed Grade I and 2 Grade II xerostomia. In contrast, in 25 amifostine-treated patients there was no significant (p=0.691) decrease in parenchymal function following high-dose radioiodine treatment, and xerostomia did not occur in any of them. Conclusion: Parenchymal damage of salivary glands induced by high-dose radioiodine treatment can be significantly reduced by amifostine which may improve quality of life of patients with differentiated thyroid cancer. (orig.) [German] Hintergrund und Ziel: Eine Schaedigung der Speicheldruesen mit konsekutiver Xerostomie ist eine bekannte, durch freie Radikale verursachte Nebenwirkung der ablativen Radioiodtherapie bei Patienten mit differenziertem Schilddruesenkarzinom. Daher wurde der Effekt des Radikalfaengers Amifostin bei ablativer Radioiodtherapie geprueft. Patienten und Methoden: Es wurden insgesamt 50

  19. Comparing Whole Building Energy Implications of Sidelighting Systems with Alternate Manual Blind Control Algorithms

    Directory of Open Access Journals (Sweden)

    Christopher Dyke

    2015-05-01

    Full Text Available Currently, there is no manual blind control guideline used consistently throughout the energy modeling community. This paper identifies and compares five manual blind control algorithms with unique control patterns and reports blind occlusion, rate of change data, and annual building energy consumption. The blind control schemes detailed here represent five reasonable candidates for use in lighting and energy simulation based on difference driving factors. This study was performed on a medium-sized office building using EnergyPlus with the internal daylight harvesting engine. Results show that applying manual blind control algorithms affects the total annual consumption of the building by as much as 12.5% and 11.5% for interior and exterior blinds respectively, compared to the Always Retracted blinds algorithm. Peak demand was also compared showing blind algorithms affected zone load sizing by as much as 9.8%. The alternate algorithms were tested for their impact on American Society of Heating, Refrigeration and Air-Conditioning Engineers (ASHRAE Guideline 14 calibration metrics and all models were found to differ from the original calibrated baseline by more than the recommended ±15% for coefficient of variance of the mean square error (CVRMSE and ±5% for normalized mean bias error (NMBE. The paper recommends that energy modelers use one or more manual blind control algorithms during design stages when making decisions about energy efficiency and other design alternatives.

  20. 75 FR 32484 - Array-Based Cytogenetic Tests: Questions on Performance Evaluation, Result Reporting and...

    Science.gov (United States)

    2010-06-08

    ...] Array-Based Cytogenetic Tests: Questions on Performance Evaluation, Result Reporting and Interpretation... public meeting: Array-Based Cytogenetic Tests: Questions on Performance Evaluation, Result Reporting and... cytogenetic tests. Date and Time: The meeting will be held on June 30, 2010, from 1:30 p.m. to 5 p.m. Location...