WorldWideScience

Sample records for biomolecules equipment design

  1. Dental operatory design and equipment.

    Science.gov (United States)

    Floyd, M

    1993-08-01

    Improving and expanding the dental services of a practice can involve purchasing new equipment and even modifying or expanding the physical plant. Operatory design is important to the efficiency with which dental procedures can be performed. Equipment purchases to outfit the dental operatory should be made based on the specific needs and functions of a practice.

  2. 21 CFR 58.61 - Equipment design.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Equipment design. 58.61 Section 58.61 Food and... PRACTICE FOR NONCLINICAL LABORATORY STUDIES Equipment § 58.61 Equipment design. Equipment used in the... of appropriate design and adequate capacity to function according to the protocol and shall...

  3. 40 CFR 160.61 - Equipment design.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Equipment design. 160.61 Section 160... LABORATORY PRACTICE STANDARDS Equipment § 160.61 Equipment design. Equipment used in the generation... appropriate design and adequate capacity to function according to the protocol and shall be suitably...

  4. 40 CFR 792.61 - Equipment design.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 31 2010-07-01 2010-07-01 true Equipment design. 792.61 Section 792.61...) GOOD LABORATORY PRACTICE STANDARDS Equipment § 792.61 Equipment design. Equipment used in the... of appropriate design and adequate capacity to function according to the protocol and shall...

  5. Hot conditioning equipment conceptual design report

    Energy Technology Data Exchange (ETDEWEB)

    Bradshaw, F.W., Westinghouse Hanford

    1996-08-06

    This report documents the conceptual design of the Hot Conditioning System Equipment. The Hot conditioning System will consist of two separate designs: the Hot Conditioning System Equipment; and the Hot Conditioning System Annex. The Hot Conditioning System Equipment Design includes the equipment such as ovens, vacuum pumps, inert gas delivery systems, etc.necessary to condition spent nuclear fuel currently in storage in the K Basins of the Hanford Site. The Hot Conditioning System Annex consists of the facility of house the Hot Conditioning System. The Hot Conditioning System will be housed in an annex to the Canister Storage Building. The Hot Conditioning System will consist of pits in the floor which contain ovens in which the spent nuclear will be conditioned prior to interim storage.

  6. Hot conditioning equipment conceptual design report

    International Nuclear Information System (INIS)

    This report documents the conceptual design of the Hot Conditioning System Equipment. The Hot conditioning System will consist of two separate designs: the Hot Conditioning System Equipment; and the Hot Conditioning System Annex. The Hot Conditioning System Equipment Design includes the equipment such as ovens, vacuum pumps, inert gas delivery systems, etc.necessary to condition spent nuclear fuel currently in storage in the K Basins of the Hanford Site. The Hot Conditioning System Annex consists of the facility of house the Hot Conditioning System. The Hot Conditioning System will be housed in an annex to the Canister Storage Building. The Hot Conditioning System will consist of pits in the floor which contain ovens in which the spent nuclear will be conditioned prior to interim storage

  7. Optimization of biomolecule separation by combining microscale filtration and design-of-experiment methods.

    Science.gov (United States)

    Kazemi, Amir S; Kawka, Karina; Latulippe, David R

    2016-10-01

    There is considerable interest in developing microscale (i.e., high-throughput) methods that enable multiple filtration experiments to be run in parallel with smaller sample amounts and thus reduce the overall required time and associated cost to run the filtration tests. Previous studies to date have focused on simply evaluating the filtration capacity, not the separation performance. In this work, the stirred-well filtration (SWF) method was used in combination with design-of-experiment (DOE) methods to optimize the separation performance for three binary mixtures of bio-molecules: protein-protein, protein-polysaccharide, and protein-DNA. Using the parallel based format of the SWF method, eight constant-flux ultrafiltration experiments were conducted at once to study the effects of stirring conditions, permeate flux, and/or solution conditions (pH, ionic strength). Four separate filtration tests were conducted for each combination of process variables; in total, over 100 separate tests were conducted. The sieving coefficient and selectivity results are presented to match the DOE design format and enable a greater understanding of the effects of the different process variables that were studied. The method described herein can be used to rapidly determine the optimal combination of process factors that give the best separation performance for a range of membrane-based separations applications and thus obviate the need to run a large number of traditional lab-scale tests. Biotechnol. Bioeng. 2016;113: 2131-2139. © 2016 Wiley Periodicals, Inc. PMID:27563852

  8. Improving the hygienic design of closed equipment

    DEFF Research Database (Denmark)

    Friis, Alan; Jensen, Bo Boye Busk

    2005-01-01

    Maintenance of proper hygiene in closed process equipment is in many ways a complex task. The interaction between the physical design and the nature of fluid flow is of main concern. During cleaning the main performance of the flow is to bring cleaning agents in the right doses to all parts...... cleaning action of fluid flow and the interaction between flow characteristics and soil attached to surfaces. Ideally, such information can be contained in fluid dynamics models or rules of thumb which can be used to assist in design of process equipment and when optimising cleaning procedures. Extending...... of the process plant. In turn the adhesion mechanisms between the soil and the surface of the process equipment must be overcome. In closed processes validation proves rather difficult, as inspection often is not possible. Hence, we benefit from a greater basic understanding of the influence of the mechanical...

  9. ITER L 7 duct remote handling equipment design report

    International Nuclear Information System (INIS)

    The operation, design and interfaces of the 'Duct Vehicle' and it's associated remote handling equipment are briefly described in this document. This equipment is being designed by Spar Aerospace Ltd. for the Divertor Test Platform as part of ITER Research and Development Project L-7. Canadian Fusion Fuels Technology Project funds this work as part of the Canadian Contribution to ITER. This document describes the equipment design status at the September 1996 design review. 23 figs

  10. Design report for cask transportation equipment

    International Nuclear Information System (INIS)

    In Korea, the spent fuels stored in the spent fuel storage pools in the domestic nuclear power plants significantly affects the continuation of the power plant operation. To solve this problem, KAERI has developed KSC-4 spent fuel shipping cask, which can transport 4 PWR spent fuel assemblies. Besides the development of the cask, KAERI developed transportation equipment which needed to use of KSC-4 cask. These equipment consist of cask handling tools such as lifting yoke, lid handling tool and spent fuel handling tool, etc. and transportation equipment such as trailer. In this report the usages, structures and functions of these tools and equipment were described, and the safety evaluation was carried out for each equipment

  11. Towards structured integration of maintenance knowledge in industrial equipment design

    OpenAIRE

    Mulder, W; Basten, R.J.I.; Jauregui Becker, J.M.; Dongen, van, C.J.J.; Lindemann, Udo; Venkataraman, Srinivasan; Kim, Yong Se

    2013-01-01

    Industrial equipment requires maintenance to remain operational. The level of maintenance that is required, and how easily it can be executed, is affected by the characteristics of the equipment. Therefore, design decisions have a strong influence on the effectiveness and efficiency of the maintenance process. Ideally, the design of the equipment should be aligned with the design of the maintenance service. Relevant knowledge about the relationships between them is available in both the liter...

  12. Conceptual design report, CEBAF basic experimental equipment

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1990-04-13

    The Continuous Electron Beam Accelerator Facility (CEBAF) will be dedicated to basic research in Nuclear Physics using electrons and photons as projectiles. The accelerator configuration allows three nearly continuous beams to be delivered simultaneously in three experimental halls, which will be equipped with complementary sets of instruments: Hall A--two high resolution magnetic spectrometers; Hall B--a large acceptance magnetic spectrometer; Hall C--a high-momentum, moderate resolution, magnetic spectrometer and a variety of more dedicated instruments. This report contains a short description of the initial complement of experimental equipment to be installed in each of the three halls.

  13. A source for microhydrated biomolecules

    Energy Technology Data Exchange (ETDEWEB)

    Förstel, M.; Hergenhahn, U., E-mail: uwe.hergenhahn@ipp.mpg.de [Max-Planck-Institut für Plasmaphysik, Wendelsteinstraße 1, 17491 Greifswald (Germany); Neustetter, M.; Denifl, S. [Institut für Ionenphysik und Angewandte Physik, Technikerstraße 25, 6020 Innsbruck (Austria); Lelievre, F. [Max-Planck-Institut für Plasmaphysik, Wendelsteinstraße 1, 17491 Greifswald (Germany); University Paris-Sud 11, Faculté des Science d’Orsay, 91405 Orsay (France)

    2015-07-15

    We describe the construction of an apparatus for the production of a molecular jet of microhydrated biomolecules. Our design uses a water reservoir producing water vapour, which then passes through a separate reservoir containing a vapour of a sublimated biomolecule. The mixture coexpands into a molecular beam apparatus through a conical nozzle. Mass spectra showing water-adenin and water-uracil complexes are shown as typical examples. Suitable expansion conditions are reached without the use of an inert carrier gas.

  14. Design and Development of Carborne Survey Equipment

    Directory of Open Access Journals (Sweden)

    Syarbaini

    2015-08-01

    Full Text Available In most nuclear and radiological emergencies involving the release of radioactive materials to environment, it is important that data on the geographic distribution of potentially hazardous radioactive materials be quickly presented to the authorities. The mobile radiation detection system makes it possible to measure radioactive materials in the environment at random places because of its easy mobility from place to place. The purpose of the work is to develop a mobile radiation detection system to measure gamma exposure rate, radioactive material on the ground and airborne radioactive particulate in the environment quickly. In this work, we have developed a carborne survey equipment system consisting of three gamma ray detectors, one airbome radioactive particulate sampler, a GPS (Global Positioning System, meteorological sensors, a data acquisition system and an operation software. Performance of the carborne survey equipment has been successfully demonstrated to measure iodine and argon release from medical isotope production facility on Serpong in western Java, Indonesia.

  15. Maintainability design criteria for packaging of spacecraft replaceable electronic equipment.

    Science.gov (United States)

    Kappler, J. R.; Folsom, A. B.

    1972-01-01

    Maintainability must be designed into long-duration spacecraft and equipment to provide the required high probability of mission success with the least cost and weight. The ability to perform repairs quickly and easily in a space environment can be achieved by imposing specific maintainability design criteria on spacecraft equipment design and installation. A study was funded to investigate and define design criteria for electronic equipment that would permit rapid removal and replacement in a space environment. The results of the study are discussed together with subsequent simulated zero-g demonstration tests of a mockup with new concepts for packaging.

  16. Recent advancements in nanotechnological strategies in selection, design and delivery of biomolecules for skin regeneration.

    Science.gov (United States)

    Korrapati, Purna Sai; Karthikeyan, K; Satish, Aishwarya; Krishnaswamy, Venkat Raghavan; Venugopal, Jayarama Reddy; Ramakrishna, Seeram

    2016-10-01

    Skin is a very complex organ and hence designing a bioengineered skin model replicating the essential physiological characteristics for replacing the diseased or damaged parts has been a challenging goal for many. Newer technologies for satisfying most of the criteria are being attempted with the copious efforts of biologists, engineers, physiologists, using multitude of features in combination. Amongst them nanotechnology based biomaterials have gained prominence owing to the enhanced pharmacokinetics, bio-distribution profile, extended half-life and reduced side effects. Designing a matrix that can be assimilated into the body during the regeneration and delivering the essential pharmacological agents in a temporal and spatially specific manner is a tremendous goal. This review essentially deals with the various approaches for designing a multidisciplinary translational smart matrix for addressing the various skin related ailments. PMID:27287175

  17. Equipment design guidance document for flammable gas waste storage tank new equipment

    International Nuclear Information System (INIS)

    This document is intended to be used as guidance for design engineers who are involved in design of new equipment slated for use in Flammable Gas Waste Storage Tanks. The purpose of this document is to provide design guidance for all new equipment intended for application into those Hanford storage tanks in which flammable gas controls are required to be addressed as part of the equipment design. These design criteria are to be used as guidance. The design of each specific piece of new equipment shall be required, as a minimum to be reviewed by qualified Unreviewed Safety Question evaluators as an integral part of the final design approval. Further Safety Assessment may be also needed. This guidance is intended to be used in conjunction with the Operating Specifications Documents (OSDs) established for defining work controls in the waste storage tanks. The criteria set forth should be reviewed for applicability if the equipment will be required to operate in locations containing unacceptable concentrations of flammable gas

  18. Towards structured integration of maintenance knowledge in industrial equipment design

    NARCIS (Netherlands)

    Mulder, W.; Basten, R.J.I.; Jauregui Becker, J.M.; Dongen, van L.A.M.; Lindemann, Udo; Venkataraman, Srinivasan; Kim, Yong Se

    2013-01-01

    Industrial equipment requires maintenance to remain operational. The level of maintenance that is required, and how easily it can be executed, is affected by the characteristics of the equipment. Therefore, design decisions have a strong influence on the effectiveness and efficiency of the maintenan

  19. Concurrent Design Study of the Petroleum Equipment CAD System

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    Military petroleum equipment, as the special device a nd tool for petroleum storage, transportation, filling, chemical analysis, detec tion and maintenance for the army, is an important means and basis of petroleum indemnificatory. To adapt to modern war in high-tech conditions, the petroleum equipment have to develop towards higher reliability, adaptability, maneuverabil ity, standardization, container and cell type with versatile multi-functions. As a new design theory and design process, concur...

  20. The design and manufacture of the catalyst test equipment

    Energy Technology Data Exchange (ETDEWEB)

    Cho, J. H.; Song, I. T. [Korea Atomic Energy Research Institute, Taejeon (Korea)

    2000-02-01

    The object of this report is to design and manufacture of the catalyst test equipment for removing tritium(H3) included in heavy water for the heavy water reactor. The design conditions of the reactor with the test equipment are summarized as follows 1) Flow rate : 336 l/min. 2) Pressure : 1.15kg/cm{sup 2}. 3) Maximum Temperature : 80 deg C. The test equipment is composed of the water jacket reactor, water equilibrator, heaters, condensers, tanks and pumps. As well as, it is composed of the water, hydrogen, helium, vacuum, emergency operation and control systems. This report will be used important data for the design and manufacture of the equipment for removing tritium. 30 tabs. (Author)

  1. Engineering design guidelines for electromagnetic pulse hardening of naval equipment

    Science.gov (United States)

    Rogers, S. R.; Perala, R. A.; Rosich, R. K.; Cook, R. B.; Rudolph, T. H.

    1981-07-01

    This document is intended to be used by engineers who design and manufacture shipboard equipment. It is complete in the sense that both the EMP hazard and the means of mitigating the hazard (hardening) are presented. The hazard is described, which not only discusses EMP generation in a general sense, but it also presents specific threat levels for EMP fields and transient currents and voltages included on cables and antennas which are connected to electronic equipment. This specific threat constitutes an EMP survivability criteria which must be met by the mission critical equipment. The necessary hardening technology areas include volume shielding, cable shielding and connectors, interface susceptibility analysis, terminal protective devices, upset and upset hardening, common mode rejection techniques, optical isolation, and grounding/bonding techniques. Test techniques which can verify equipment hardness are presented along with methods to observe the equipment's hardness and maintain the hardness.

  2. Reliable design of electronic equipment an engineering guide

    CERN Document Server

    Natarajan, Dhanasekharan

    2014-01-01

    This book explains reliability techniques with examples from electronics design for the benefit of engineers. It presents the application of de-rating, FMEA, overstress analyses and reliability improvement tests for designing reliable electronic equipment. Adequate information is provided for designing computerized reliability database system to support the application of the techniques by designers. Pedantic terms and the associated mathematics of reliability engineering discipline are excluded for the benefit of comprehensiveness and practical applications. This book offers excellent support

  3. Design review report for modifications to RMCS safety class equipment

    Energy Technology Data Exchange (ETDEWEB)

    Corbett, J.E.

    1997-05-30

    This report documents the completion of the formal design review for modifications to the Rotary Mode Core Sampling (RMCS) safety class equipment. These modifications are intended to support core sampling operations in waste tanks requiring flammable gas controls. The objective of this review was to approve the Engineering Change Notices affecting safety class equipment used in the RMCS system. The conclusion reached by the review committee was that these changes are acceptable.

  4. Design of equipment management information system for nuclear power plant

    International Nuclear Information System (INIS)

    The author describes the ideas and practical method for need analysis, system function dividing, code design, program design and network disposition of equipment purchase management system of nuclear power plant during building, from the view of engineering investment control, schedule control and quality control

  5. Verification of the thermal design of electronic equipment

    Energy Technology Data Exchange (ETDEWEB)

    Hienonen, R.; Karjalainen, M.; Lankinen, R. [VTT Automation, Espoo (Finland). ProTechno

    1997-12-31

    The project `Verification of the thermal design of electronic equipment` studied the methodology to be followed in the verification of thermal design of electronic equipment. This project forms part of the `Cool Electronics` research programme funded by TEKES, the Finnish Technology Development Centre. This project was carried out jointly by VTT Automation, Lappeenranta University of Technology, Nokia Research Center and ABB Industry Oy VSD-Technology. The thermal design of electronic equipment has a significant impact on the cost, reliability, tolerance to different environments, selection of components and materials, and ergonomics of the product. This report describes the method for verification of thermal design. It assesses the goals set for thermal design, environmental requirements, technical implementation of the design, thermal simulation and modelling, and design qualification testing and the measurements needed. The verification method covers all packaging levels of electronic equipment from the system level to the electronic component level. The method described in this report can be used as part of the quality system of a corporation. The report includes information about the measurement and test methods needed in the verification process. Some measurement methods for the temperature, flow and pressure of air are described. (orig.) Published in Finnish VTT Julkaisuja 824. 22 refs.

  6. Engineering electrodynamics electric machine, transformer, and power equipment design

    CERN Document Server

    Turowski, Janusz

    2013-01-01

    Due to a huge concentration of electromagnetic fields and eddy currents, large power equipment and systems are prone to crushing forces, overheating, and overloading. Luckily, power failures due to disturbances like these can be predicted and/or prevented.Based on the success of internationally acclaimed computer programs, such as the authors' own RNM-3D, Engineering Electrodynamics: Electric Machine, Transformer, and Power Equipment Design explains how to implement industry-proven modeling and design techniques to solve complex electromagnetic phenomena. Considering recent progress in magneti

  7. The stem cell laboratory: design, equipment, and oversight.

    Science.gov (United States)

    Wesselschmidt, Robin L; Schwartz, Philip H

    2011-01-01

    This chapter describes some of the major issues to be considered when setting up a laboratory for the culture of human pluripotent stem cells (hPSCs). The process of establishing a hPSC laboratory can be divided into two equally important parts. One is completely administrative and includes developing protocols, seeking approval, and establishing reporting processes and documentation. The other part of establishing a hPSC laboratory involves the physical plant and includes design, equipment and personnel. Proper planning of laboratory operations and proper design of the physical layout of the stem cell laboratory so that meets the scope of planned operations is a major undertaking, but the time spent upfront will pay long-term returns in operational efficiency and effectiveness. A well-planned, organized, and properly equipped laboratory supports research activities by increasing efficiency and reducing lost time and wasted resources. PMID:21822863

  8. The Design of Administrative System Based On Portable Intellectual Equipment

    Institute of Scientific and Technical Information of China (English)

    Zeng,Jianhua; Chen,Haisong; Feng,Mingfa; Liang,Zhaofeng

    2005-01-01

    Regard property management of intelligentized residential area as the application background, we introduce a kind of method for the design of a management system based on portable intelligent equipments. The system is made up of intelligent terminals and personal computers. The intelligent terminals are for data collection and data storage. They communicate with personal computers through high-speed interface. The personal computers communicate with intelligent devices and carry out data analysis and data processing with VB6.0.

  9. Design of a molecular imprinting biosensor with multi-scale roughness for detection across a broad spectrum of biomolecules.

    Science.gov (United States)

    Yu, Yingjie; Zhang, Qi; Chang, Chung-Chueh; Liu, Ying; Yang, Zhenhua; Guo, Yichen; Wang, Yantian; Galanakis, Dennis K; Levon, Kalle; Rafailovich, Miriam

    2016-10-01

    The molecular imprinting technique has tremendous applications in artificial enzymes, bioseparation, and sensor devices. In this study, a novel molecular imprinting (MI) biosensor platform was developed for the detection of a broad range of biomolecules with different sizes. Previously this method has been applied to 2D molecular imprinting, where the height of the self-assembled monolayer (SAM) of around 2 nm limited the maximum dimensions of the molecule that can be imprinted to create template-shaped cavities. In order to match the size of the imprinted molecules with the height of the SAM, we propose a model for 3D molecular imprinting where the analyte is sequestered within a niche created by the surface roughness. The SAM is assembled on the walls of the niche, forming a 3D pattern of the analyte uniquely molded to its contour. Surfaces with multi-scale roughness were prepared by evaporation of gold onto electropolished (smooth) and unpolished (rough) Si wafers, where the native roughness was found to have a normal distribution centered around 5 and 90 nm respectively. Our studies using molecules with size ranging on a nanometer scale, from proteins of a few nanometers to bacteria of hundreds of nanometers, showed that when the size of the analyte matched the roughness range of the gold surface, the molecular imprinting process was optimized for the best biosensing performance. After optimization, the MI biosensor platform enabled the identification and quantification of a broad range of biomolecules with great discrimination abilities. Hemoglobin under different pH values and several mutated fibrinogen molecules can also be well differentiated through the test.

  10. Design of EPON far-end equipment based on FTTH

    Science.gov (United States)

    Feng, Xiancheng; Yun, Xiang

    2008-12-01

    Now, most favors fiber access is mainly the EPON fiber access system. Inheriting from the low cost of Ethernet, usability and bandwidth of optical network, EPON technology is one of the best technologies in fiber access and is adopted by the carriers all over the world widely. According to the scheme analysis to FTTH fan-end equipment, hardware design of ONU is proposed in this paper. The FTTH far-end equipment software design deference modulation design concept, it divides the software designment into 5 function modules: the module of low-layer driver, the module of system management, the module of master/slave communication, and the module of main/Standby switch and the module of command line. The software flow of the host computer is also analyzed. Finally, test is made for Ethernet service performance of FTTH far-end equipment, E1 service performance and the optical path protection switching, and so on. The results of test indicates that all the items are accordance with technical request of far-end ONU equipment and possess good quality and fully reach the requirement of telecommunication level equipment. The far-end equipment of FTTH divides into several parts based on the function: the control module, the exchange module, the UNI interface module, the ONU module, the EPON interface module, the network management debugging module, the voice processing module, the circuit simulation module, the CATV module. In the downstream direction, under the protect condition, we design 2 optical modules. The system can set one group optical module working and another group optical module closure when it is initialized. When the optical fiber line is cut off, the LOS warning comes out. It will cause MUX to replace another group optical module, simultaneously will reset module 3701/3711 and will make it again test the distance, and will give the plug board MPC850 report through the GPIO port. During normal mode, the downstream optical signal is transformed into the

  11. IRIS safety system and equipment design verification test plan

    International Nuclear Information System (INIS)

    The International Reactor Innovative and Secure (IRIS) is an advanced, integral, light-water cooled reactor of medium generating capacity (335 MWe), geared at near term deployment (2012-2015). IRIS is an innovative design that features an integral reactor vessel that contains all the reactor coolant system components, including the steam generators, coolant pumps, pressurizer and heaters, and control rod drive mechanisms; in addition to the: typical core, internals, control rods and neutron reflector. Other IRIS innovations also include a small, high design pressure, spherical steel containment; and a simplified passive safety system concept and equipment features that derive from its unique 'safety-by-design' IM philosophy. The IRIS ('safety-by-design')TM approach not only improves safety, but it also reduces the overall cost by allowing a significant reduction and simplification in safety systems. Moreover, IRIS improved safety supports licensing the power plant without the need for off-site emergency response planning an objective which is part of the pre-application with NRC and is also is being pursued in collaboration with IAEA. The IRIS innovative integral reactor coolant system design, as well as its innovative ('safety-by-design')TM approach features, has resulted in the need for new safety analyses and new equipment design and qualification, in order to successfully license the plant. Therefore, the IRIS design team has developed a test plan that will provide the necessary data for safety analyses verification as well as the demonstration of equipment manufacturing feasibility and operation. This paper will present the 'IRIS Safety System and Equipment Design Verification Test Plan' which develops and confirms the operation of all the IRIS unique features, and includes component manufacturing feasibility tests, component separate effects tests, component qualification tests, and integral effects tests. These tests will also provide the data necessary to

  12. Designing equipment for use in gamma radiation environments

    International Nuclear Information System (INIS)

    High levels of gamma radiation are known to cause degradation in a variety of materials and components. When designing systems to operate in a high radiation environment, special precautions and procedures should be followed. This report (1) outlines steps that should be followed in designing equipment and (2) explains the general effects of radiation on various engineering materials and components. Much information exists in the literature on radiation effects upon materials. However, very little information is available to give the designer a step-by-step process for designing systems that will be subject to high levels of gamma radiation, such as those found in a nuclear fuel reprocessing facility. In this report, many radiation effect references are relied upon to aid in the design of components and systems. 11 refs., 4 tabs

  13. Designing Equipment for Use in Gamma Radiation Environments

    Energy Technology Data Exchange (ETDEWEB)

    Vandergriff, K.U.

    1990-01-01

    High levels of gamma radiation are known to cause degradation in a variety of materials and components. When designing systems to operate in a high radiation environment, special precautions and procedures should be followed. This report (1) outlines steps that should be followed in designing equipment and (2) explains the general effects of radiation on various engineering materials and components. Much information exists in the literature on radiation effects upon materials. However, very little information is available to give the designer a step-by-step process for designing systems that will be subject to high levels of gamma radiation, such as those found in a nuclear fuel reprocessing facility. In this report, many radiation effect references are relied upon to aid in the design of components and systems.

  14. Conference on Manned Systems Design : New Methods and Equipment

    CERN Document Server

    Kraiss, K-F

    1981-01-01

    This volume contains the proceedings of a conference held in Freiburg, West Germany, September 22-25, 1980, entitled "Manned Systems Design, New Methods and Equipment". The conference was sponsored by the Special Programme Panel on Human Factors of the Scientific Affairs Division of NATO, and supported by Panel VIII, AC/243, on "Human and Biomedical Sciences". Their sponsorship and support are gratefully acknowledged. The contributions in the book are grouped according to the main themes of the conference with special emphasis on analytical approaches, measurement of performance, and simulator design and evaluat ion. The design of manned systems covers many and highly diversified areas. Therefore, a conference under the general title of "Manned Systems Design" is rather ambitious in itself. However, scientists and engineers engaged in the design of manned systems very often are confronted with problems that can be solved only by having several disciplines working together. So it was felt that knowledge about ...

  15. NATO ARI on Ergonomic Data for Equipment Design

    CERN Document Server

    1984-01-01

    For many years ergonomists and human engineering specialists have made significant contributions to the solution of problems faced in the area of human labour and to the introduction of their research results and field experience into the process of equipment design. However, the rapid increase in complexity of equipment in use as well as in development demonstrates the necessity of broaden­ ing the point of view continuously. The workshop held in Munich from March 22nd to March 26th, 1982, was an excellent opportunity for the participants to discuss their respective interests and their interpretation of needs for future research. The workshop was sponsored by the Human Factors Special Programme Panel of the Scientific Affairs Division of NATO. This sponsorship, together with the helpful assistance rendered by Drs. Bayraktar, Kroemer, and Sanders, is gratefully acknowledged. This volume contains the papers presented during the workshop. All these papers are directly related to the general aim: the ex­ chang...

  16. Biomolecules in Astrobiology

    OpenAIRE

    Meringer, Markus

    2013-01-01

    Astrobiology is the study of the origin, distribution and future of life in the universe, biomolecules are molecules produced by living organisms. This talk reviews known facts and open questions about biomolecules in the context of Astrobiology and introduces a research project on "Creating a Reference Set of Amino Acids Structures for Use in Multiple Astrobiology Investigations" that tries to find answers using computational methods.

  17. Design of remote handling equipment for the ITER NBI

    Energy Technology Data Exchange (ETDEWEB)

    Oka, Kiyoshi; Tada, Eisuke [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    1999-08-01

    The ITER machine has three Neutral Beam Injectors (NBIs) placed tangential to the plasma at a minimum radius of 6.25 m. During operation, neutrons produced by the D-T reactions will irradiate the NBI structure and it will become radioactive. Radiation levels will be such that all subsequent maintenance of the NBIs must be carried out remotely. The presence of tritium and possibly radioactive dust requires that precautions be taken during maintenance to prevent the escape of these contaminants beyond the prescribed boundaries. The scope of this task is both the development of remote maintenance procedures and the design of the remote handling equipment to handle the NBIs. This report describes the design of remote handling tools for the ion source and its filaments, transfer cask, maintenance time, manufacturing schedule and cost estimation. (author)

  18. Design of tension control system for fiber placement equipments

    Directory of Open Access Journals (Sweden)

    Hongjie CHANG

    2015-10-01

    Full Text Available Aiming at the tension control requirements of automatic fiber placement equipments and the problems of traditional tension control system, the hammer tension control system is designed. The hammer is used as a buffer unit in the system, and the tension can be indirectly controlled by the position of the hammer. The system adopts the motion controller as the core element of the system, the AC servo motor as the actuator and the laser position sensor as the detector. The fuzzy PID control algorithm is used for the position control of hammer, which can avoid tension fluctuation by full consideration of the acceleration of the hammer. Prototype experimental results show that this system can avoid the problems of disconnection and relaxation of fiber, meanwhile, the static difference ratio and fluctuation ratio can meet the requirements of engineering practice.

  19. DNV launches new recommended practice for design of subsea equipment

    Energy Technology Data Exchange (ETDEWEB)

    Toerstad, Elisabeth Heggelund

    2005-07-01

    The application of modern corrosion-resistant alloys to subsea pipelines and components has led to serious problems of hydrogen embrittlement from the corrosion protection system, resulting in cracks and leaks. The most commonly known incidents of this kind are the duplex hubs on Voinhaven, UK and Garn West and the 13% Cr pipelines on Tune and Aasgard, all at the Norwegian shelf. Understanding the nature of this problem has called for a broad multidisciplinary approach, involving expertise on corrosion and metallurgy as well as structural design and integrity. Competence in probabilistic analyses and risk assessments has also been necessary in order to set acceptance criteria and evaluate probability of failure for existing installations. (Det Norske Veritas (DNV) is now about to issues a Recommended Practise (RP) for design of subsea equipment in duplex steels under Cathodic Protection. The RP is based on knowledge gained through failure investigations, qualification pr grams and research work, and a broad industry consortium has contributed with experience and knowledge. Hydrogen Induced Stress Cracking (HISC) due to hydrogen from the Cathodic Protection (CP) system has been one of the most frequent and costly failure modes for subsea equipment and pipelines in the North Sea over the recent years. Today, the international oil business is looking to Norway for assistance in establishing detailed knowledge about and preventive measures against this failure mode. A significant research work is currently being carried out jointly by DNV, SINTEF and TWI (The Welding Institute), supported by a broad industry consortium - aiming at a better understanding of the HISC (Hydrogen Induced Stress Cracking) mechanism and establishment of test methods which reflect the sensitivity to cracking. DNV has also established a Recommended Practice, which will be issued late 2005. It reflects the experience gained from the failure examinations, fitness for purpose evaluations, research

  20. Design and Implementation of Equipment Interactive Electronic Technical Manuals

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    Interactive electronic technical manuals (IETMs) can significantly improve the maintenance and logistics of modern weapon equipment. Main functiors and development strategies of IETMs are discussed. As an example, the IETM development of a certain equipment is demonstrated.

  1. DESIGNING FEATURES OF POWER OPTICAL UNITS FOR TECHNOLOGICAL EQUIPMENT

    Directory of Open Access Journals (Sweden)

    M. Y. Afanasiev

    2016-03-01

    Full Text Available This paper considers the question of an optical unit designing for transmitting power laser radiation through an optical fiber. The aim of this work is designing a simple construction unit with minimized reflection losses. The source of radiation in the optical unit described below is an ultraviolet laser with diode pumping. We present the general functioning scheme and designing features for the three main parts: laser beam deflecting system, laser beam dump and optical unit control system. The described laser beam deflection system is composed of a moving flat mirror and a spherical scattering mirror. Comparative analysis of the production technology for such mirrors was carried out, and, as a result, the decision was made to produce both mirrors of 99.99 % pure molybdenum without coating. A moving mirror deflects laser emission from a source through a fiber or deflects it on a spherical mirror and into the laser beam dump, moreover, switching from one position to another occurs almost immediately. It is shown that a scattering mirror is necessary, otherwise, the absorbing surface of the beam dump is being worn out irregularly. The laser beam dump is an open conical cavity, in which the conical element with its spire turned to the emission source is placed. Special microgeometry of the internal surface of the beam dump is suggested for the better absorption effect. An optical unit control system consists of a laser beam deflection system, laser temperature sensor, deflection system solenoid temperature sensor, and deflection mirror position sensor. The signal processing algorithm for signals coming from the sensors to the controller is described. The optical unit will be used in special technological equipment.

  2. Experimental equipment design and testing of the DEOX process

    International Nuclear Information System (INIS)

    Several technologies exist or are under development for treating spent oxide fuels. Foremost among these are aqueous and pyrochemical reprocessing which both involve head-end fuel dissolution step. This dissolution step may potentially be shortened if it is combined with a fuel decladding and size reduction process. Declad and Oxidize (DEOX), an advanced head-end processing concept, is being assessed at Argonne National Laboratory (ANL) to meet these decladding and size reduction needs via the oxidation of UO2 to U3O8. DEOX is intended to remove the spent fuel from its cladding, while avoiding oxidation of the cladding that would contaminate the product. An additional goal is to obtain a product particle size distribution between 45 μm to 4 mm. DEOX begins with uranium oxide (UO2) spent fuel pins. Remote tools are used to cut the fuel into segments. Additional equipment is then employed to heat the segments and exposes them to oxygen. The UO2 oxidizes to U3O8 per the reaction 3UO2 + O2 = U3O8, it undergoes a corresponding volume increase, which pulverizes the fuel. This volume increase may cause the pin cladding to split, allowing fuel to escape. Mechanical sieving can further separate the pulverized fuel and cladding. The fuel may then be treated by either aqueous or pyrochemical methods, and the cladding can be disposed of through existing techniques. The DEOX experiments are planned to be run in the argon portion of the Hot Fuel Examination Facility at ANL. During the design phase, engineers identified 6 major components: 1) the fuel cutter - to chop the fuel pins to the desired length; 2) the fuel container - to hold the chopped fuel pieces during processing; 3) the furnace - to heat the fuel samples; 4) the containment vessel - to seal out argon from the hot cell but expose the fuel samples to a pure oxygen environment; 5) the off gas filter - to capture off-gases; and 6) the gas panel - to regulate air-flow and pressure. All the components of the DEOX

  3. Synchronous and Sequential Strategies in the Process Design of Cascade Equipment

    NARCIS (Netherlands)

    Groot Wassink, Jan; Rácz, Imre G.

    1976-01-01

    Cascade or multistage equipment is characterized by the repetition of similar equipment elements in series. Process design, resulting into the main geometric and kinematic dimensions of the equipment, makes use of different strategies. These strategies, based on a process description, the (equality-

  4. Investigating Lay Design through Prototyping a Toolkit for Audio Equipment

    OpenAIRE

    Hermans, Guido

    2015-01-01

    Post-industrial design challenges the current way of design and production of consumer products. Leveraging from 3D printing and the potential of layperson involvement in the design process, we investigated how the relation between the professional designer and layperson might change in a democratized design process, where the layperson is an active participant, mediated by toolkit software. In this research through design study we examined this relation by prototyping a toolkit for audio equ...

  5. Manual on Safety Aspects of the Design and Equipment of Hot Laboratories

    International Nuclear Information System (INIS)

    With the development of atomic energy application and research, hot laboratories are now being constructed in a number of countries. The present publication describes and discusses experience in several countries in designing equipment for these laboratories. The safe handling of highly radioactive substances is the main purpose of hot laboratory design and equipment. The manual aims at helping those persons, particularly in the developing countries, who plan to design and construct a new hot laboratory or modify an existing one. It does not deal in great detail with the engineering design of protective and handling equipment; these matters can be found in the comprehensive list of references. The manual itself covers only basic ideas and different approaches in the design of laboratory building, hot cells, shielded and glove boxes, fume cupboards, and handling and viewing equipment. Systems for transferring materials and main services are also discussed.

  6. Design of highwall mining equipment electronic guidance package

    Energy Technology Data Exchange (ETDEWEB)

    Brenden, B.B.; Morgen, G.P.; Shorpik, J.R.; Farrar, R.

    1981-11-01

    This report provides design specifics and guidance software for a guidance system intended for use in guiding an auger type highwall mining head through thin coal seams to depths of up to 600 ft. A small desk top computer is used at the operator's station to send and receive signals in serialized bit streams to a downhole microprocessor. The guidance system accepts signals from a variety of sensors and uses these signals to plot and control the course of the auger head automatically using computer algorithms designed to keep the auger head in the coal seam and maintain a specified stump thickness.

  7. The optimization design of nuclear measurement teaching equipment

    International Nuclear Information System (INIS)

    So far domestic student-oriented experimental nuclear measuring instruments are used only to measure object density, thickness or material level, and in the choice of sources activity is mostly about 10 mCi. this design will proposed a optimization program dealing with domestic situation. It discussed the radioactive sources activity, the structural design of sealed sources, such as the choice of the tested material in order to get a program optimization. The program used 1 mCi activity radioactive sources 137Cs to reduce the radiation dose, and the measurement function was improved. So that the apparatus can measure density, thickness nad material level. (authors)

  8. Structuring of Information Base for Designing Fire Equipment

    OpenAIRE

    Zinko, Roman

    2015-01-01

    Proper ordering and structuring help process large volumes of knowledge quickly, identify key trends and changes in design, and offer effective solutions of the current issues. Using term by term disjunction allows processing large amounts of knowledge, and representation of the predicate presented as a graph provides a clear visualization. The example of the application of the above-mentioned method while creating a new fire truck to fight forest fires is provided.

  9. Subirrigation equipment for the production of citrus rootstocks: Design and hydraulic assessment

    Directory of Open Access Journals (Sweden)

    Conan Ayade Salvador

    2014-12-01

    Full Text Available The aim of this study was to design and characterize hydraulic subirrigation equipment for the citrus rootstocks production of to allow the water capillary rise for the seedling stage. This equipment was designed since the citrus seedling phase occurs in plastic containers with substrate, and because there is a need to increase the irrigation efficiency in this sector. The methodology consisted of: (i identification and characterization of the irrigation methods used in the citrus rootstocks production; (ii the design of subirrigation equipment prototype; and, (iii the construction and hydraulic evaluation of the prototype equipment. After a model was designed, 10 prototypes were built with two different dimensions (44 × 29 × 15 cm and 62 × 41 × 15 cm, and the theoretical and experimental relationships of flow and operating pressure were determined. The proposed equipment was designed according to engineering criteria that allows its evaluation for commercial use, although additional field trials are required for its final adjustment. Moreover, the theoretical equation of flow rate was validated for small-immersed orifices in thin walls, as an operational condition of the developed subirrigation equipment.

  10. Improvements of seismic design of nuclear power plant equipment

    Energy Technology Data Exchange (ETDEWEB)

    Suzuki, Kohei [Tokyo Metropolitan Univ., Hachioji (Japan). Faculty of Technology; Takayama, Yoshihiro

    1997-03-01

    A brief survey and overview of the current research and development in Japan was presented. Particularly, several kinds of new dampers and isolators were developed and those effectiveness were examined by caring out the large-scale vibration test and so on. The evaluation of the energy absorption of these damping devices at the earthquake appeared to be significant. In addition, it must be necessary to investigate the design margin and the failure mode and limit problem to these devices and the nuclear structures and piping supported by those. Mutual exchange of the information related to these technology and research has to be put forward and cooperative works including the international conference on those issues should be promoted. (J.P.N.)

  11. Improvements of seismic design of nuclear power plant equipment

    International Nuclear Information System (INIS)

    A brief survey and overview of the current research and development in Japan was presented. Particularly, several kinds of new dampers and isolators were developed and those effectiveness were examined by caring out the large-scale vibration test and so on. The evaluation of the energy absorption of these damping devices at the earthquake appeared to be significant. In addition, it must be necessary to investigate the design margin and the failure mode and limit problem to these devices and the nuclear structures and piping supported by those. Mutual exchange of the information related to these technology and research has to be put forward and cooperative works including the international conference on those issues should be promoted. (J.P.N.)

  12. Human-centered design of the human-system interfaces of medical equipment: thyroid uptake system

    Energy Technology Data Exchange (ETDEWEB)

    Monteiro, Jonathan K.R.; Farias, Marcos S.; Santos, Isaac J.A. Luquetti, E-mail: luquetti@ien.gov.br [Instituto de Engenharia Nuclear (IEN/CNEN-RJ), Rio de Janeiro, RJ (Brazil); Monteiro, Beany G. [Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro, RJ (Brazil). Dept. de Desenho Industrial

    2013-07-01

    Technology plays an important role in modern medical centers, making healthcare increasingly complex, relying on complex technical equipment. This technical complexity is particularly noticeable in the nuclear medicine. Poorly design human-system interfaces can increase the risks for human error. The human-centered approach emphasizes the development of the equipment with a deep understanding of the users activities, current work practices, needs and abilities of the users. An important concept of human-centered design is that the ease-of-use of the equipment can be ensured only if users are actively incorporated in all phases of the life cycle of design process. Representative groups of users are exposed to the equipment at various stages in development, in a variety of testing, evaluation and interviewing situations. The users feedback obtained is then used to refine the design, with the result serving as input to the next interaction of design process. The limits of the approach are that the users cannot address any particular future needs without prior experience or knowledge about the equipment operation. The aim of this paper is to present a methodological framework that contributes to the design of the human-system interfaces, through an approach related to the users and their activities. A case study is described in which the methodological framework is being applied in development of new human-system interfaces of the thyroid uptake system. (author)

  13. Equipment and design changes in extrusion of foamed fluoropolymer resins

    Science.gov (United States)

    Randa, S. K.; Carlson, M. A.; Reifschneider, D. P.

    Recent growth of computer networks has increased the market for foamed coaxial cables. To meet this need, the gas injection process for foaming of Teflon* FEP and PFA fluorocarbon resins introduced in 1981 at the 30th Wire and Cable Symposium has been refined. Advances in die and extruder screw design have broadened capability from 500 CATV coaxial cable to miniature wire sizes. Increased processing speeds and higher core quality have been achieved. These coaxial cables have a unique combination of properties that are maintained over a wide range of temperatures and signal frequencies. They have dielectric constants as low as 1.3 and low flame spread and smoke generation as tested to UL 910. These cables are now widely used for high frequency signal transmission in compliance with the National Electric Code for installation without conduit in building air handling plenums. Military applications represent newer areas of interest with weight and space savings and high electrical quality. The characteristics of several coaxial cables are reviewed.

  14. Performance based design of structures, systems and equipment in Indian nuclear power plants

    International Nuclear Information System (INIS)

    Nuclear power plants in India have been designed for earthquake resistance by the methods of analysis and testing. Many of the electrical and instrumentation equipment have been tested on shake tables available in India. The performance of the civil structures, piping systems, cable trays, ducting and mechanical, electrical, instrumentation and control equipment in industries around Koyna (1967, 6.5 M), Bhuj (2001, 7.6 M) and Muzaffarabad (2005, 7.6 M) which have witnessed the earthquake is also available

  15. Design/Operations review of core sampling trucks and associated equipment

    International Nuclear Information System (INIS)

    A systematic review of the design and operations of the core sampling trucks was commissioned by Characterization Equipment Engineering of the Westinghouse Hanford Company in October 1995. The review team reviewed the design documents, specifications, operating procedure, training manuals and safety analysis reports. The review process, findings and corrective actions are summarized in this supporting document

  16. Seismic design of equipment and piping systems for nuclear power plants in Japan

    Energy Technology Data Exchange (ETDEWEB)

    Minematsu, Akiyoshi [Tokyo Electric Power Co., Inc. (Japan)

    1997-03-01

    The philosophy of seismic design for nuclear power plant facilities in Japan is based on `Examination Guide for Seismic Design of Nuclear Power Reactor Facilities: Nuclear Power Safety Committee, July 20, 1981` (referred to as `Examination Guide` hereinafter) and the present design criteria have been established based on the survey of governmental improvement and standardization program. The detailed design implementation procedure is further described in `Technical Guidelines for Aseismic Design of Nuclear Power Plants, JEAG4601-1987: Japan Electric Association`. This report describes the principles and design procedure of the seismic design of equipment/piping systems for nuclear power plant in Japan. (J.P.N.)

  17. Design Report of Volume Reduction and Handling Equipment of ACPF Wastes

    Energy Technology Data Exchange (ETDEWEB)

    Kwon, K. C.; Ku, J. H.; Lee, W. K.; Lee, E. P.; Choung, W. M.; Cho, I. J.; Kook, D. H.; You, G. S.; Youn, J. S

    2007-01-15

    For the efficient disposal of wastes from the ACPF (Advanced spent fuel Conditioning Process Facility), hot cell filter press equipment, vacuum press equipment of compatible wastes and hot cell auxiliary crane were developed. The filter press equipment installed in hot cell is pneumatically driven and remotely operated. In order to avoid the contamination of hot cell by dust particles from filters being compressed, it is designed to compress filters with them put into the basket of the solid wastes cask. The performance test showed that the height of a filter was reduced by more than 75% and a basket could contain up to four compressed filters. The vacuum press equipment reduces the volume of the plastic bag containing compatible wastes such as cloth, plastic film and paper by vacuumizing the bag. It consists of the vacuum pump, the suction and HEPA filters and the manual pneumatic valve, and is designed to be easily handled and managed. Through the performance test, it is observed that the volume of wastes was reduced to a third. Also an additional crane of 300 kg capacity was manufactured and installed in the ACP hot cell to handle the salt ingot wastes container located where the overhead crane is not accessible. This report presenting the details of the design, manufacturing and performance of these equipment will be used as technical materials for the operation of the facility and the development of equipment.

  18. Preliminary design report for prototypical spent nuclear fuel rod consolidation equipment

    International Nuclear Information System (INIS)

    The purpose of the Prototypical Consolidation Demonstration Project (PCDP) is to develop and demonstrate the equipment system that will be used to consolidate the bulk of the spent nuclear fuel generated in the United States prior to its placement in a geological repository. The equipment must thus be capable of operating on a routine production basis over a long period of time with stringent requirements for safety, reliability, productivity and cost-effectiveness. Four phases are planned for the PCDP. Phase 1 is the Preliminary Design of generic consolidation equipment that could be installed at a Monitored Retrievable Storage (MRS) facility or in the Receiving ampersand Handling Facility at a geologic repository site. Phase 2 will be the Final Design and preparation of procurement packages for the equipment in a configuration capable of being installed and tested in a special enclosure within the TAN Hot Shop at DOE's Idaho National Engineering Laboratory. In Phase 3 the equipment will be fabricated and then tested with mock fuel elements in a contractor's facility. Finally, in Phase 4 the equipment will be moved to the TAN facility for demonstration operation with irradiated spent fuel elements. 55 figs., 15 tabs

  19. Design and construction of the Portable Industrial X-Ray Equipment

    International Nuclear Information System (INIS)

    The main purposes of the project are the supporting to design and construction of the Portable Industrial X-Ray Equipment; with the accuracy ±2% of Output High Voltage 200 kV and Tube current 5 mA. The Equipment is composed of control unit, X-ray generator, and power cable, connection cable. X-ray generator is assembling construction X-ray tube, H.V transformer together with gas insulation (SF6) are sealed up in aluminum bucked cabinet, fan and heat-sink are mounted in the end of X-ray generator as cooling, SF6 is a gas electrical performance to H.V. Alarm lamp is used to warn, flashing, show generating X-ray. Control unit is box construction. Four printed circuit boards (PCB) and electronic device are mounted in it. All operating buttons switches and displays are equipped on the panel. We have completed to design and construct the Portable Industrial X-Ray Equipment; and have tested the electronic parameters of all test points and the main parameters of equipment (the accuracy ±2% of Output High Voltage 200 kV and Tube current 5 mA). We also have successful used the Portable Industrial X-Ray Equipment to evaluate the welds in industry. (author)

  20. Design and Construction of the Portable Industrial X-Ray Equipment

    International Nuclear Information System (INIS)

    The main purposes of the project are the supporting to design and construction of the Portable Industrial X-Ray Equipment; with the accuracy ±2% of Output High Voltage 200 kV and Tube current 5 mA. The Equipment is composed of control unit, X-ray generator, and power cable, connection cable. X-ray generator is assembling construction X-ray tube, H.V transformer together with gas insulation (SF6) are sealed up in aluminum bucked cabinet, fan and heat-sink are mounted in the end of X-ray generator as cooling, SF6 is a gas electrical performance to H.V. Alarm lamp is used to warn, flashing, show generating X-ray. Control unit is box construction. Four printed circuit boards (PCB) and electronic device are mounted in it. All operating buttons switches and displays are equipped on the panel. We have completed to design and construct the Portable Industrial X-Ray Equipment; and have tested the electronic parameters of all test points and the main parameters of equipment (the accuracy ±2% of Output High Voltage 200 kV and Tube current 5 mA). We also have successful used the Portable Industrial X-Ray Equipment to evaluate the welds in industry. (author)

  1. Design of a Prognostics and Health Management System for Electromechanical Equipment Through Time Stress Analysis

    Institute of Scientific and Technical Information of China (English)

    L(U) Ke-hong; QIU Jing; LIU Guan-jun

    2008-01-01

    Time stress includes all kinds of environment and operating stress such as shock, vibration, temperature and electric current that the electromechanical system suffers in the manufacture, transport and operating process. In this paper, the conception of time stress and prognostics and health management (PHM) system are introduced. Then, in order to improve the false alarm recognition and fault prediction capabilities of the electromechanical equipment, a novel PHM architecture for electromechanical equipment is put forward based on a built-in test (BIT) system design technology and time stress analysis method. Finally, the structure, the design and implementing method and the functions of each module of this PHM system are described in detail.

  2. Power system engineering planning, design, and operation of power systems and equipment

    CERN Document Server

    Schlabbach, Juergen

    2014-01-01

    With its focus on the requirements and procedures of tendering and project contracting, this book enables the reader to adapt the basics of power systems and equipment design to special tasks and engineering projects, e.g. the integration of renewable energy sources.

  3. Prototypical spent fuel rod consolidation equipment preliminary design report: Volume 2, Drawings

    International Nuclear Information System (INIS)

    This volume consists of 65 E size drawings and 4 sketches of the NUS spent fuel rod consolidation equipment. The drawings have been grouped into categories; a detailed list of the drawings is included. The sketches prepared during the preliminary design process have been included

  4. 78 FR 13911 - Proposed Revision to Design of Structures, Components, Equipment and Systems

    Science.gov (United States)

    2013-03-01

    ... COMMISSION Proposed Revision to Design of Structures, Components, Equipment and Systems AGENCY: Nuclear.... Amy E. Cubbage, Office of New Reactors, U.S. Nuclear Regulatory Commission, Washington, DC 20555- 0001... ADAMS. II. Further Information The Office of New Reactors and Office of Nuclear Reactor Regulation...

  5. 78 FR 15755 - Proposed Revision to Design of Structures, Components, Equipment and Systems; Correction

    Science.gov (United States)

    2013-03-12

    ... of New Reactors, U.S. Nuclear Regulatory Commission, Washington, DC 20555- 0001; telephone: 301-415... From the Federal Register Online via the Government Publishing Office NUCLEAR REGULATORY COMMISSION Proposed Revision to Design of Structures, Components, Equipment and Systems; Correction...

  6. 78 FR 48727 - Proposed Revisions to Design of Structures, Components, Equipment and Systems

    Science.gov (United States)

    2013-08-09

    ... From the Federal Register Online via the Government Publishing Office NUCLEAR REGULATORY COMMISSION Proposed Revisions to Design of Structures, Components, Equipment and Systems AGENCY: Nuclear.... FOR FURTHER INFORMATION CONTACT: Jonathan DeGange, Office of New Reactors, U.S. Nuclear...

  7. 78 FR 41434 - Proposed Revisions to Design of Structures, Components, Equipment and Systems

    Science.gov (United States)

    2013-07-10

    ... From the Federal Register Online via the Government Publishing Office NUCLEAR REGULATORY COMMISSION Proposed Revisions to Design of Structures, Components, Equipment and Systems AGENCY: Nuclear.... FOR FURTHER INFORMATION CONTACT: Mr. Jonathan DeGange, Office of New Reactors, U.S. Nuclear...

  8. On Syllabus Design for the Specialty of Electromechanical Equipment Maintenance and Management in Vocational College

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    We carried out researches on the syllabus design for the specialty of electromechanical equipment maintenance & management in vocational college. Our researches involve the following aspects: (1) The training objective of the specialty; (2) the curriculum system; (3) The teaching methodology; and (4) Field training.

  9. Design and tests of the screw denitration equipment using microwave heating

    International Nuclear Information System (INIS)

    A continuous denitration equipment which uses a microwave heating technique is designed and tested. A screw is incorporated for feeding material. Major features of this technique include easiness of pellet molding due to high activity of powder, decreased amount of waste and waste liquid released and easy operation and maintenance due to simplified processes. The equipment consists of a solution supply pipe, denitrated material discharge pipe, microwave guide, offgas exhaust pipe and screw feeder, all of which are connected to a denitration oven. Tests are performed for determining microwave absorption efficiency, processing capacity and performance. Cerium nitrate solution is employed as sample to simulate uranyl nitrate solution. Parameters used include the solution retention volume, inclination of the screw shaft, clearance between the screw and the trough, and solution concentration. The maximum microwave absorption efficiency is found to be 50 percent. Measurements also show that the equipment requires 3.5 - 4.5 hours to reach a stationary state. The size of dried material depends on the revolution speed of the screw. In the performance confirmation test, the equipment is operated continuously for 52 hours while measuring the fluctuation in the torque of the screw motor shaft and the properties of dried material discharged. Results show that the equipment can operate continuously while meeting the design conditions. (Nogami, K.)

  10. Design of Robust Systems for Stabilization of Unmanned Aerial Vehicle Equipment

    Directory of Open Access Journals (Sweden)

    Olha Sushchenko

    2016-01-01

    Full Text Available The paper deals with the structural synthesis of robust system for stabilization of observation equipment operated on unmanned aerial vehicles. The model of the triaxial stabilization system taking into consideration necessary kinematic transformations is developed. The matrix weighting transfer functions ensuring design of the system with the desired amplitude-frequency characteristics of the system are chosen. The features of the robust structural synthesis for the researched system are considered. The structure and parameters of the robust controller, based on robust structural synthesis including the methods of the mixed sensitivity and loop-shaping, are obtained. The results of the synthesized system simulation are represented. The obtained results allow implementing stabilization of observation equipment in difficult conditions of real operation. This improves the quality of photography, mapping, survey, and so forth and gives advantages of accuracy for images representations of the territory flown. The obtained results are significant for stabilization of equipment operated at a moving base.

  11. Mechanical design for positioning of GM detector for system of avian flu virus detection equipment

    International Nuclear Information System (INIS)

    Mechanical design for positioning of GM detector system has been done. It is used for avian flu detection equipment. The requirements for the design are to protect detection system against shock, portable, and easy to maintain. The mechanical system consists of connectors, cable assemblies, holders, casing, housing and detectors cover. The selected material should have small gamma radiation absorption property in order to give optimum counts for the detector. The design result should give a system that is easy to operate, cheap and easy to assemble. (author)

  12. A mechanical design for positioning of gm detector for system of avian flu virus detection equipment

    International Nuclear Information System (INIS)

    Mechanical design for positioning of GM detector system has been done. It is used for avian flu detection equipment. The requirements for the design are to protect detection system against shock, portable, and easy to maintain. The mechanical system consists of connectors, cable assemblies, holders, casing, housing and detectors cover. The selected material should have small gamma radiation absorption property in order to give optimum counts for the detector. The design result should give a system that is easy to operate, cheap and easy to assemble. (author)

  13. Design of phantoms and software for automatic image analysis applied to digital radiographic equipments

    International Nuclear Information System (INIS)

    In a quality control of the radiographic equipment, the quality of the obtained image is very useful to characterize the physical properties of the image radiographic chain. In the radiographic technique it is necessary that the evaluation of the image can guarantee the constancy of its quality to carry out a suitable diagnosis. The use of digital systems allows the automatic analysis of the obtained radiographic images, increasing the objectivity in the evaluation of the image. In this work we have designed some radiographic phantoms for different radiographic digital devices, as dental, conventional, equipments with computed radiography (phosphor plate) and direct radiography (sensor) technology. Additionally, we have developed a software to analyse the image obtained by the radiographic equipment with digital processing techniques as edge detector, morphological operators, statistical test for the detected combinations.. The images have been acquired in DICOM, tiff.. format and they can be analysed with objective parameters as an image quality index and the contrast detail curve. The design of these phantoms let the evaluation of a wide range of operating conditions of voltage, current and time of the digital equipments. Moreover, the image quality analysis by the automatic software let study it with objective parameters and the functioning of the image chain of the digital system. (author)

  14. Prototypical spent fuel rod consolidation equipment preliminary design report: Volume 1, Report

    International Nuclear Information System (INIS)

    This design report describes the NUS Preliminary Design of the Prototype Spent Nuclear Fuel Rod Consolidation Equipment for the Department of Energy. The sections of the report elaborate on each facet of the preliminary design. A concept summary is provided to assist the reader in rapidly understanding the complete design. The NUS Prototype Spent Fuel Rod Consolidation System is an automatically controlled system to consolidate a minimum of 750 MT (heavy metal)/year of US commercial nuclear reactor fuel, at 75% availability. The system is designed with replaceable components utilizing the latest state-of-the-art technology. This approach gives the system the flexibility to be developed without costly development programs, yet accept new technology as it evolves over the next ten years. Capability is also provided in the system design to accommodate a wide variety of fuel conditions and to recover from any situation which may arise

  15. Design and implementation of equipment for monitoring the salinity in the subsoil

    Directory of Open Access Journals (Sweden)

    Mariano Norzagaray Campos

    2012-09-01

    Full Text Available Geochemical exploration equipments to explore the contaminants and structures geological in the subsoil come from abroad are expensive and sometimes parts for replacement are not available in the market. So it is necessary design apparatus that meet cover these needs. To the monitoring of variations in salinity there is semi-automatic equipment, but it always has difficult to manage. However, is not equipment for the indirect study of salinity in the subsoil. In this work was design equipment for measurement the apparent resistivity in the subsoil, at same time allow know the salinity, as well as the detection of any pollutant in groundwater. For make it, was selected a design of earthing systems, with electronic hardware which were jointed for apply to subsoil a direct current (DC through an array dipole-dipole and vertical electric sounding, with brass and stainless steel electrodes. In the earthing systems the electrodes were collocated in the equidistant line between the detectors of potential and current. A geometric factor (K, that depend on theelectrodes distance and direct current (I injected in the electrodes A and B, was used for measure the potential difference between the electrodes M and N; after was calculate the resistivity point to point for obtain a subsoil tomography geoelectrical. The equipment was calibrated with minimum error (rms < 2% whit respect to curves obtained in similar commercial equipment. On this situation, in this work was modernized and automated an equipment to determine thesalinity of the subsoil. The instrument was tasted in the micro basin Texcoco, State of Mexico, to define the environment geometry formed by alluvial or lake sediments from igneous rocks (andesites, rhyolites and tuffs vitreous or “tepetates” which by its mineralogical composition allowed to the lateral resistivity be associate with free components trace from the aquifer: Cd, Cu, Cr, Co, Ni, Pb or Zn and others. This method constitutes

  16. 48 CFR 52.246-19 - Warranty of Systems and Equipment under Performance Specifications or Design Criteria.

    Science.gov (United States)

    2010-10-01

    ... Equipment under Performance Specifications or Design Criteria. 52.246-19 Section 52.246-19 Federal... under Performance Specifications or Design Criteria. As prescribed in 46.710(c)(1), the contracting officer may insert a clause substantially as follows: Warranty of Systems and Equipment Under...

  17. Equipment Design and Cost Estimation for Small Modular Biomass Systems, Synthesis Gas Cleanup, and Oxygen Separation Equipment; Task 2.3: Sulfur Primer

    Energy Technology Data Exchange (ETDEWEB)

    Nexant Inc.

    2006-05-01

    This deliverable is Subtask 2.3 of Task 2, Gas Cleanup Design and Cost Estimates, of NREL Award ACO-5-44027, ''Equipment Design and Cost Estimation for Small Modular Biomass Systems, Synthesis Gas Cleanup and Oxygen Separation Equipment''. Subtask 2.3 builds upon the sulfur removal information first presented in Subtask 2.1, Gas Cleanup Technologies for Biomass Gasification by adding additional information on the commercial applications, manufacturers, environmental footprint, and technical specifications for sulfur removal technologies. The data was obtained from Nexant's experience, input from GTI and other vendors, past and current facility data, and existing literature.

  18. Identifying the essential factors in the marketing mix design (The case of Personal Protective Equipment)

    OpenAIRE

    2012-01-01

    This research intends to focus on establishing an easier methodology for determining a marketing mix that a startup company can use. It can also help established companies in an early phase assessment of their marketing mix. The study focuses on this methodology through the case of PPE (Personal Protective Equipment) by identifying the essential factors in the marketing mix design for it. Marketing a product requires that the product has a right mix of all the four P’s- Product, Place, Price ...

  19. ABS test equipment design%ABS 测试设备设计

    Institute of Scientific and Technical Information of China (English)

    王宇鹏

    2013-01-01

      This article simply introduces the structure and operating principle of ABS. and a new equipment for ABS signal testing is designed and put into use.%  简要介绍了 ABS 的组成及其工作原理,并结合自身情况,设计了测试 ABS 信号的设备,并投入使用。

  20. Analysis of possible schemes for twisting multiwire superconducting cables and design of twisting equipment

    International Nuclear Information System (INIS)

    Possible technological schemes for obtaining superconducting twisted cables are presented. The advantages and disadvantages of the twisting schemes and deformations of the superconduct ing wires when being twisted are analyzed. The causes of the twist step instabilities are considered and recommendations on choosing the twisting scheme satisfying the requirements imposed on the twisted cables are presented. Brief information on the designed and used in industry equipment for superconductor twisting is given. 8 refs.; 8 figs.; 2 tabs

  1. Research and Design of Sleeve Detach and Reunion Drive Mechanism of Screw Melt Extruder Equipment

    Institute of Scientific and Technical Information of China (English)

    Xiude ZHANG

    2012-01-01

    The design of sleeve detach and reunion drive device of screw melt ex- truder equipment was optimized, based on the present installation of hygraulic drive device to achieve the mechanical opening and closing of the sleeve, the dynamic model of the sleeve detach and reunion drive was theoretically measured, and it was verified that the device is simple to operate and convenient to maintain, thus it has great social values.

  2. Thermally modulated biomolecule transport through nanoconfined channels

    Science.gov (United States)

    Liu, Lei; Zhu, Lizhong

    2015-04-01

    In this work, a nanofluidic device containing both a feed cell and a permeation cell linked by nanopore arrays has been fabricated, which is employed to investigate thermally controlled biomolecular transporting properties through confined nanochannels. The ionic currents modulated by the translocations of goat antibody to human immunoglobulin G (IgG) or bovine serum albumin (BSA) are recorded and analyzed. The results suggest that the modulation effect decreases with the electrolyte concentration increasing, while the effects generated by IgG translocation are more significant than that generated by BSA translocation. More importantly, there is a maximum decreasing value in each modulated current curve with biomolecule concentration increasing for thermally induced intermolecular collision. Furthermore, the turning point for the maximum shifts to lower biomolecule concentrations with the system temperature rising (from 4°C to 45°C), and it is mainly determined by the temperature in the feed cell if the temperature difference exists in the two separated cells. These findings are expected to be valuable for the future design of novel sensing device based on nanopore and/or nanopore arrays.

  3. Research and design of the main equipments and structure of Xiangjiaba shiplift

    Institute of Scientific and Technical Information of China (English)

    Liao Lekang; Zhu Hong; Zhang Rui

    2014-01-01

    The type of pinion and rack vertical shiplifts has been developed in recent a couple of years in the construction of dams. But the design methods and methodologies have rarely been discussed in literature. The Xiangjiaba shiplift is the second shiplift of this type following the Three Gorges shiplift. Being aimed at the technological rationality of the design in synthetically considering security,economy and applicability,this pa-per presents the research results of some vital issues relating the design of the Xiangjiaba shiplift,including the determination of design water depth of ship chamber based on fluid numeral computation and physical model test,the optimum design of general layout of main equipments and the civil structure of the Xiangjiaba shiplift, the finite element method (FEM) analysis of stress,vibration modes and the buckling of ship chamber,anti-seismic research and the design of structures and mechanisms of the shiplift and the optimum design of driving mechanisms. This research provides the theoretical basis for the design of the Xiangjiaba shiplift. The design principles and research methods are valuable for the design of the same type of shiplifts.

  4. Design and installation of extra high voltage cryogenic dielectric test facilities for the superconducting electric equipment

    International Nuclear Information System (INIS)

    We installed high voltage cryogenic dielectric test facilities including big FRP cryostat. We designed 3 m long and 2 m wide cryostat system with busing. Low temperature and high voltage bushing were fabricated and tested. CF4 gas shows excellent characteristics in low temperature insulation. High voltage bushing could be modified for low temperature environment. Superconducting electric equipments have a lot of advantages over the conventional devices such as improvements in overall efficiency, size reduction, high current carrying capability, and also environment-friendly products. Owing to these advantages, many research institutes have been tried to develop commercial superconducting devices, which could be applicable to the high voltage and high current electric networks. But up to now, most of the research works to develop commercial products were delayed because it was not easy to acquire reliable high voltage insulation properties and optimum insulation design skills considering extremely low temperature environments. Furthermore, it was difficult to determine optimum high voltage insulation level due to the lack of high voltage cryogenic dielectric test facilities. Thus, in order to establish the cryogenic dielectric technology regarding insulating design, cryogenic dielectric test skills, and to implement more reliable high voltage superconducting devices, high voltage cryogenic dielectric test facilities should be prepared for extra high voltage superconducting electric equipments. Recently, cryogenic dielectric test facilities were installed including 3 m long 2 m wide cryostat system with bushing, and 1.6 MVA lightening impulse generators, 400 kVA AC overvoltage test system in Korea. In this paper, design and installation of high voltage cryogenic dielectric test system including very big size FRP cryostat and high voltage bushing were minutely introduced. And some test results to develop high voltage bushings for liquid nitrogen cryostat in order to

  5. Design validation of the 4S high temperature electromagnetic pump by one pole segment test equipment

    International Nuclear Information System (INIS)

    The small fast reactor 4S (Super Safe Small and Simple) adopts high temperature sodium immersed electromagnetic pump (EMP) as a primary pump. The reason is that EMP is able to satisfy the low maintenance, safety and reliability requirements for 4S, because it has simple structure and no moving parts. Technical challenges of 4S EMP are the following three items.The first is to confirm manufacturability of 4S EMP. 4S EMP has the world greatest dimension coil and stator and flattened shape with the aspect ratio (outer diameter / stator length) of 1.8. The 4S prototype EMP as same as practical dimension and the one pole segment test equipment were manufactured in JFY 2008. The second is to construct the back up power supply system for flow coast down. It will be confirmed by combination test of 4S prototype EMP and the system in JFY 2010. The third is to confirm low maintenance for 30 years. A part of long-term soundness test of coil is tested by heat cycle test with one pole test equipment discussed in the next section. Furthermore, as the future development subject, the seismic assessment and the long-term soundness test of the EMP body by the sodium fluid test has been planned. The one pole segment test equipment is used for evaluation of following items. The first is the integrity of the electrical insulation of large diameter coil. Insulation breakdown will be estimated due to thermal expansion in coil during operation, thus, the heat cycle is loaded to the equipment simulating start-and-stop of 4S. Insulation resistance, leak current and tan δ will also be measured in several steps of coil temperature. The second is validation whether stator support system of the EMP would work as designed. In practical 4S EMP, all of Joule heat by energization of the coil during operation is transferred into sodium through core and duct. To keep the heat transfer system, in the outer stator, the core is pressed upon the duct by spring plates. Therefore, it is important to

  6. Study on compact design of remote handling equipment for ITER blanket maintenance

    International Nuclear Information System (INIS)

    In the ITER, the neutrons created by D-T reactions activate structural materials, and thereby, the circumstance in the vacuum vessel is under intense gamma radiation field. Thus, the in-vessel components such as blanket are handled and replaced by remote handling equipment. The objective of this report is to study the compactness of the remote handling equipment (a vehicle/manipulator) for the ITER blanket maintenance. In order to avoid the interferences between the blanket and the equipment during blanket replacement in the restricted vacuum vessel, a compact design of the equipment is required. Therefore, the compact design is performed, including kinematic analyses aiming at the reduction of the sizes of the vehicle equipped with a manipulator handling the blanket and the rail for the vehicle traveling in the vacuum vessel. Major results are as follows: 1. The compact vehicle/manipulator is designed concentration on the reduction of the rail size and simplification of the guide roller mechanism as well as the reduction of the gear diameter for vehicle rotation around the rail. Height of the rail is reduced from 500 mm to 400 mm by a parameter survey for weight, stiffness and stress of the rail. The roller mechanism is divided into two simple functional mechanisms composed of rollers and a pad, that is, the rollers support relatively light loads during rail deployment and vehicle traveling while a pad supports heavy loads during blanket replacement. Regarding the rotation mechanism, the double helical gear is adopted, because it has higher contact ratio than the normal spur gear and consequently can transfer higher force. The smaller double helical gear, 996 mm in diameter, can achieve 26% higher output torque, 123.5 kN·m, than that of the original spur gear of 1,460 mm in diameter, 98 kN·m. As a result, the manipulator becomes about 30% lighter, 8 tons, than the original weight, 11.2 tons. 2. Based on the compact design of the vehicle/manipulator, the

  7. Repository Planning, Design, and Engineering: Part II-Equipment and Costing.

    Science.gov (United States)

    Baird, Phillip M; Gunter, Elaine W

    2016-08-01

    Part II of this article discusses and provides guidance on the equipment and systems necessary to operate a repository. The various types of storage equipment and monitoring and support systems are presented in detail. While the material focuses on the large repository, the requirements for a small-scale startup are also presented. Cost estimates and a cost model for establishing a repository are presented. The cost model presents an expected range of acquisition costs for the large capital items in developing a repository. A range of 5,000-7,000 ft(2) constructed has been assumed, with 50 frozen storage units, to reflect a successful operation with growth potential. No design or engineering costs, permit or regulatory costs, or smaller items such as the computers, software, furniture, phones, and barcode readers required for operations have been included. PMID:26886768

  8. A Knowledge-Based Approach for Selection of Material Handling Equipment and Material Handling System Pre-design

    OpenAIRE

    YAMAN, Ramazan

    2001-01-01

    For material handling system design, material handling equipment selection is the first stage. Also the material handling system and facility layout design problems are coupled. Solving these problems needs consideration of these three different problems. Right material handling equipment selection and good design of the material handling system and facility layout can increase productivity and reduce investments and operations' costs. In this study, after describing the mater...

  9. Equipment Design and Cost Estimation for Small Modular Biomass Systems, Synthesis Gas Cleanup, and Oxygen Separation Equipment; Task 9: Mixed Alcohols From Syngas -- State of Technology

    Energy Technology Data Exchange (ETDEWEB)

    Nexant Inc.

    2006-05-01

    This deliverable is for Task 9, Mixed Alcohols from Syngas: State of Technology, as part of National Renewable Energy Laboratory (NREL) Award ACO-5-44027, ''Equipment Design and Cost Estimation for Small Modular Biomass Systems, Synthesis Gas Cleanup and Oxygen Separation Equipment''. Task 9 supplements the work previously done by NREL in the mixed alcohols section of the 2003 technical report Preliminary Screening--Technical and Economic Assessment of Synthesis Gas to Fuels and Chemicals with Emphasis on the Potential for Biomass-Derived Syngas.

  10. Project and design of apparatus and equipment of pilot plant experimental bituminization line PS 44 EBO

    International Nuclear Information System (INIS)

    The modifications are described made in the design of major components of the pilot plant experimental bituminization line involving: the mixing equipment, the film rotor evaporator, the calciner, and various transport mechanisms for handling drums and containers. The difficulty and complexity of the problem which Kralovopolska strojirna Brno, the end supplier of the bituminization line, will have to tackle is evident mainly from the case of bridge cranes, which feed the line, and the full-portal gantry crane which handles the containers and drums at regional sites of radioactive waste disposal. (Z.M.)

  11. Re-evaluation of seismic design for JOYO buildings and equipments

    Energy Technology Data Exchange (ETDEWEB)

    Isozaki, K.; Tomita, N. [Power Reactor and Nuclear Fuel Development Corp., Oarai, Ibaraki (Japan). Oarai Engineering Center

    1997-07-01

    Hyougo-ken southern earthquake broke out in 1997/01/17. The Atomic Energy Safety Commission considered reasonable of the design guide for seismic design. And the Science and Technology Agency (STA) required reevaluation of atomic power facilities built by old design guide according to the new seismic design guide. JOYO obtained the construction license in 1970/02. Heat transport system and buildings of JOYO was re-evaluated by the new seismic design guide for the MK-III project. So, JOYO was not required re-evaluation by STA. But, this evaluation of MK-III was limited to reconstruction area, and the seismic design was reevaluated extensively to confirm earthquake proof characteristics. The structural integrity of buildings and equipments was confirmed by the result of reevaluation by the new seismic design guide. The analysis model conditions were established according to the 1987 and 1991 version of JEAG. This was done by ground investigation result and buildings vibration test. It was made clear that the analysis model conditions were reasonable and conservative from a technical view point. (author)

  12. Design for Reliability of Complex System: Case Study of Horizontal Drilling Equipment with Limited Failure Data

    Directory of Open Access Journals (Sweden)

    Morteza Soleimani

    2014-01-01

    Full Text Available Reliability is an important phase in durable system designs, specifically in the early phase of the product development. In this paper, a new methodology is proposed for complex systems’ design for reliability. Specific test and field failure data scarcity is evaluated here as a challenge to implement design for reliability of a new product. In the developed approach, modeling and simulation of the system are accomplished by using reliability block diagram (RBD method. The generic data are corrected to account for the design and environment effects on the application. The integral methodology evaluates reliability of the system and assesses the importance of each component. In addition, the availability of the system was evaluated using Monte Carlo simulation. Available design alternatives with different components are analyzed for reliability optimization. Evaluating reliability of complex systems in competitive design attempts is one of the applications of this method. The advantage of this method is that it is applicable in early design phase where there is only limited failure data available. As a case study, horizontal drilling equipment is used for assessment of the proposed method. Benchmarking of the results with a system with more available failure and maintenance data verifies the effectiveness and performance quality of presented method.

  13. Design, characterization and applications of new ionic liquid matrices for multifunctional analysis of biomolecules: A novel strategy for pathogenic bacteria biosensing

    Energy Technology Data Exchange (ETDEWEB)

    Abdelhamid, Hani Nasser [Department of Chemistry, National Sun Yat-Sen University, Kaohsiung, 804, Taiwan (China); Department of Chemistry, Assuit University, Assuit, 71515 (Egypt); Khan, M Shahnawaz [Doctoral Degree Program in Marine Biotechnology, National Sun Yat-Sen University, Kaohsiung, 804, Taiwan (China); Wu, Hui-Fen, E-mail: hwu@faculty.nsysu.edu.tw [Department of Chemistry, National Sun Yat-Sen University, Kaohsiung, 804, Taiwan (China); School of Pharmacy, College of Pharmacy, Kaohsiung Medical University, Kaohsiung, 800, Taiwan (China); Institute of Medical Science and Technology, National Sun Yat-Sen University, Kaohsiung, 804, Taiwan (China); Doctoral Degree Program in Marine Biotechnology, National Sun Yat-Sen University, Kaohsiung, 804, Taiwan (China); Center for Nanoscience and Nanotechnology, National Sun Yat-Sen University, Kaohsiung, 804, Taiwan (China)

    2014-05-01

    Highlights: • Design and characterize novel UV absorbed-ionic liquid matrices series. • Apply the new series for different analytes. • Introduce a novel methodology for pathogenic bacteria biosensing. • Tabulate the physical parameters of the new series. - Abstract: The design, preparation and performance for novel UV-light absorbing (room-temperature) ionic liquid matrices (UV-RTILMs) for matrix assisted laser desorption/ionization mass spectrometry (MALDI-MS) were reported. A series of UV-RTILMs was prepared by ultrasonication of equimolar of acid (mefenamic acid) and bases (aniline (ANI), pyridine (Pyr), dimethyl aniline (DMANI) and 2-methyl picoline (2-P)). The UV-RTILMs have not only significant absorbance at the desired wavelength (337 nm of the N{sub 2} Laser), but also have available protons that can easily undergo proton transfer reactions to ionize the target molecules. The novel UV-RTILMs have the ability to ionize different and wide classes of compounds such as drugs, carbohydrate, and amino acids. The new UV-RTILMs series have been successfully and selectively applied for biosensing the lysates of pathogenic bacteria in the presence of the cell macromolecules. A new strategy for biosensing pathogens was presented via sensing the pathogens lysate in the cell suspension. The new materials can effectively detect the bacterial toxins without separation or any pretreatment. They offered excellent ionization of labile oligosaccharides with protonated peaks. They could significantly enhance the analyte signals, produce homogeneous spotting, reducing spot-to-spot variation, excellent vacuum stability, higher ion peak intensity, and wide application possibility. The physical parameters such as molar refractivity, molar volume, parachor, surface tension, density and polarizability were calculated and tabulated. The new UV-RTILMs could offer excellent reproducibility and great repeatability and they are promising matrices for wide applications on MALDI-MS.

  14. Effect of extraction solvents on the biomolecules and antioxidant properties of Scorzonera undulata (Asteraceae: Application of factorial design optimization phenolic extraction

    Directory of Open Access Journals (Sweden)

    Khaled Athmouni

    2015-12-01

    Full Text Available Background. Phenolic compounds were extracted and isolated from S. undulata roots. Methods. Sample of roots from E. hirta was tested for phenolic compounds, and in vitro antioxidant activity by diphenyl-1-picrylhydrazyl (DPPH assay, ABTS, FRAP and reducing power was measured using cyano- ferrate method. Results. The methanolic fraction exhibited the highest total phenol content (6.12 ±0.11 mg AGE/g DW. On the other hand, the highest flavonoids concentration was observed in ethyl acetate fraction (2.90 ±0.05 mg CE/g DW in addition to anthocyanins (28.56 ±3.96 mg/l. Besides, the highest level of tannins content was measured in the polar aprotic solvent ethyl acetate extract (3.25 ±0.06 mg CE/g DW. The different extracts of S. undulata were evaluated for their radical scavenging activities by means of the DPPH assay. The strongest scavenging activity was observed in methanolic fraction scavenged radicals effectively with IC   values of 0.14 ±0.02 mg/ml. Similarly, the potassium ferricyanide reduction (FRAP and ABTS•+ of methanol extract. On the other hand, the total reducing power of ethyl acetate extract was found higher than of other extracts. This paper presents the application of the design-of experiment method for optimizing the extraction of phe- nolic content using methanol solvent. The resulting regression model has shown that the effect of temperature is not statistically significant (with >95% certainty, while that of agitation speed is. The two main effects are contributed by the solvent concentration and the maceration period. Conclusion. Our results clearly showed that the extraction of phenolic compounds and their antioxidant ca- pacity is significantly affected by solvent combinations. S. undulata presented the highest total phenolic con- tent, total flavonoids content and antioxidant capacity values. The resulting regression model has shown that the effect of temperature is not statistically significant (with >95

  15. Cell and biomolecule delivery for regenerative medicine

    International Nuclear Information System (INIS)

    Regenerative medicine is an exciting field that aims to create regenerative alternatives to harvest tissues for transplantation. In this approach, the delivery of cells and biological molecules plays a central role. The scaffold (synthetic temporary extracellular matrix) delivers cells to the regenerative site and provides three-dimensional environments for the cells. To fulfil these functions, we design biodegradable polymer scaffolds with structural features on multiple size scales. To enhance positive cell-material interactions, we design nano-sized structural features in the scaffolds to mimic the natural extracellular matrix. We also integrate micro-sized pore networks to facilitate mass transport and neo tissue regeneration. We also design novel polymer devices and self-assembled nanospheres for biomolecule delivery to recapitulate key events in developmental and wound healing processes. Herein, we present recent work in biomedical polymer synthesis, novel processing techniques, surface engineering and biologic delivery. Examples of enhanced cellular/tissue function and regenerative outcomes of these approaches are discussed to demonstrate the excitement of the biomimetic scaffold design and biologic delivery in regenerative medicine. (topical review)

  16. Design of process cell equipment layout and its associated piping in typical nuclear fuel reprocessing plant

    International Nuclear Information System (INIS)

    Nuclear fuel reprocessing plant processes spent nuclear fuel discharged from the nuclear reactor to separate chemically the uranium and plutonium. Spent nuclear fuel emits radiation due to the presence of fission products, actinides and activation products. The major operation steps in reprocessing plant are dismantling of spent fuel subassemblies, chopping of fuel pins and dissolution in concentrated nitric acid. Subsequently, this solution containing uranium and plutonium, fission products and actinides is subjected to solvent extraction with tributyl phosphate in diluent as solvent for separating uranium and plutonium from fission products and other actinides. In the design of a fuel reprocessing plant, apart from problems associated with conventional chemical process industries such as corrosion, materials handling, industrial and fire safety and economy, specific considerations such as health hazards from radioactivity (radiological safety) and damage to material by radiation are considered. This necessitates the processing of spent fuel inside the shielded process cells (concrete and lead cells) with remote operation and maintenance philosophy to prevent the contamination as well as radiation exposure to the operators and prevention of criticality in process tanks and equipments. Reprocessing plant consists of number of shielded process cells depending on the processing capacity and type of spent fuel handled. Concrete cells and lead cells houses various type of storage tanks, equipments, liquid transfer devices, etc with interconnecting small bore pipe lines for liquid transfer and supply of services, which runs in multiple layers, forming a high density piping inside the cells. In addition to this, cells have remote handling systems and gadgets for remote operation and maintenance wherever required. This paper highlights the design of process cells, its equipment layout and piping in typical reprocessing plant; the suitable material of construction

  17. Development of the graphic design and control system based on a graphic simulator for the spent fuel dismantling equipment

    International Nuclear Information System (INIS)

    In this study, the graphic design system is developed for designing the spent fuel rod consolidation and the dismantling processes. This system is used throughout the design stages from the conceptual design to the motion analysis. Also, the real-time control system of the rod extracting equipment is developed. This system utilizes the graphic simulator which simulates the motion of the equipment in real time by synchronously connecting the control PC with the graphic server through the TCP/IP network. The developed system is expected to be used as an effective tool in designing the process equipment for the spent fuel management. And the real-time graphic control system can be effectively used to enhance the reliability and safety of the spent fuel handling process by providing the remote monitoring function of the process

  18. Development of the graphic design and control system based on a graphic simulator for the spent fuel dismantling equipment

    Energy Technology Data Exchange (ETDEWEB)

    Lee, J. Y.; Kim, S. H.; Song, T. G.; Yoon, J. S

    2000-06-01

    In this study, the graphic design system is developed for designing the spent fuel rod consolidation and the dismantling processes. This system is used throughout the design stages from the conceptual design to the motion analysis. Also, the real-time control system of the rod extracting equipment is developed. This system utilizes the graphic simulator which simulates the motion of the equipment in real time by synchronously connecting the control PC with the graphic server through the TCP/IP network. The developed system is expected to be used as an effective tool in designing the process equipment for the spent fuel management. And the real-time graphic control system can be effectively used to enhance the reliability and safety of the spent fuel handling process by providing the remote monitoring function of the process.

  19. Design and Experiment on Self-propelled Precise Feeding Equipment for Dairy Cow

    Directory of Open Access Journals (Sweden)

    Hewei Meng

    2013-04-01

    Full Text Available Designed a kind of self-propelled precise feeding machine for single dairy cow based on the technology of RFID, to achieve the automation,fine and intelligent of dairy farming.The computer was used as the information management platform, MCU was used as control platform, even using wireless transmission, RFID recognition, infrared detection technology and so on, which achievement the information data of wireless transmission,precise recognition and detection cattle position.It is applied to equal-diameter and variable-pitch screw feeding structure to realize the precise concentrated feed supply, equipment performance test shown that the system speed 60rpm is the most stable when feeding, feeding accuracy not less than 97.5%, to meet the feeding requirements, equipped with the best traveling speed is 0.6m/s, the response time of the system is 0.4s, the recognition rate is 96%; through one-month feeding experiment in the dairy cow farm showed that the milk production was increased, the average daily milk yield of individual cows improve 0.8kg than artificial feeding.

  20. An approach to human-centered design of nuclear medical equipment: the system of caption of the thyroid

    Energy Technology Data Exchange (ETDEWEB)

    Santos, Isaac J.A. Luquetti; Silva, Carlos Borges da; Santana, Marcos; Carvalho, Paulo Victor R.; Oliveira, Mauro Vitor de; Mol, Antonio Carlos Mol; Grecco, Claudio Henrique; Augusto, Silas Cordeiro [Instituto de Engenharia Nuclear (IEN) , Rio de Janeiro, RJ (Brazil)]. E-mail: luquetti@ien.gov.br; borges@ien.gov.br; msantana@ien.gov.br; paulov@ien.gov.br; mvitor@ien.gov.br; mol@ien.gov.br; grecco@ien.gov.br; silas@ien.gov.br

    2005-07-01

    Technology plays an important role in modern medical centers, making health care increasingly complex, relying on complex technical equipment. This technical complexity is particularly noticeable in the nuclear medicine and can increase the risks for human error. Human error has many causes such as performance shaping factors, organizational factors and user interface design. Poorly design human system interfaces of nuclear medical equipment can increase the risks for human error. If all nuclear medical equipment had been designed with good user interfaces, incidents and accidents could be reduced as well as he time required to learn how to use the equipment. Although some manufacturers of nuclear medical equipment have already integrate human factors principles in their products, there is still a need to steer the development of nuclear medical technology toward more human-centered approach. The aim of this paper is to propose a methodology that contributes to the design, development and evaluation of nuclear medical equipment and human system interface, towards a human-centered approach. This methodology includes the ergonomic approach, based on the operator activity analysis, together with human factors standards and guidelines, questionnaires and user based testing. We describe a case study in which this methodology is being applied in evaluation of the thyroid uptake system, getting essential information and data, that ill be used in development of a new system. (author)

  1. An approach to human-centered design of nuclear medical equipment: the system of caption of the thyroid

    International Nuclear Information System (INIS)

    Technology plays an important role in modern medical centers, making health care increasingly complex, relying on complex technical equipment. This technical complexity is particularly noticeable in the nuclear medicine and can increase the risks for human error. Human error has many causes such as performance shaping factors, organizational factors and user interface design. Poorly design human system interfaces of nuclear medical equipment can increase the risks for human error. If all nuclear medical equipment had been designed with good user interfaces, incidents and accidents could be reduced as well as he time required to learn how to use the equipment. Although some manufacturers of nuclear medical equipment have already integrate human factors principles in their products, there is still a need to steer the development of nuclear medical technology toward more human-centered approach. The aim of this paper is to propose a methodology that contributes to the design, development and evaluation of nuclear medical equipment and human system interface, towards a human-centered approach. This methodology includes the ergonomic approach, based on the operator activity analysis, together with human factors standards and guidelines, questionnaires and user based testing. We describe a case study in which this methodology is being applied in evaluation of the thyroid uptake system, getting essential information and data, that ill be used in development of a new system. (author)

  2. GroPBS: Fast Solver for Implicit Electrostatics of Biomolecules

    OpenAIRE

    Bertelshofer, Franziska; Sun, Liping; Greiner, Günther; Böckmann, Rainer A.

    2015-01-01

    Knowledge about the electrostatic potential on the surface of biomolecules or biomembranes under physiological conditions is an important step in the attempt to characterize the physico-chemical properties of these molecules and, in particular, also their interactions with each other. Additionally, knowledge about solution electrostatics may also guide the design of molecules with specified properties. However, explicit water models come at a high computational cost, rendering them unsuitable...

  3. Design requirements under development of equipment complex for plastic tubes welding

    International Nuclear Information System (INIS)

    Principles of formation of equipment complex for plastic tube working are determined and its properties are described. A seris of similar mounting portable (transportable) equipment and the main forming units of shop stationary equipment are taken as examples. Ways of improving developments on the basis of suggested principles have been assigned. 4 refs.; 5 figs

  4. Max Tech and Beyond: Maximizing Appliance and Equipment Efficiency by Design

    Energy Technology Data Exchange (ETDEWEB)

    Desroches, Louis-Benoit; Garbesi, Karina

    2011-07-20

    It is well established that energy efficiency is most often the lowest cost approach to reducing national energy use and minimizing carbon emissions. National investments in energy efficiency to date have been highly cost-effective. The cumulative impacts (out to 2050) of residential energy efficiency standards are expected to have a benefit-to-cost ratio of 2.71:1. This project examined energy end-uses in the residential, commercial, and in some cases the industrial sectors. The scope is limited to appliances and equipment, and does not include building materials, building envelopes, and system designs. This scope is consistent with the scope of DOE's appliance standards program, although many products considered here are not currently subject to energy efficiency standards. How much energy could the United States save if the most efficient design options currently feasible were adopted universally? What design features could produce those savings? How would the savings from various technologies compare? With an eye toward identifying promising candidates and strategies for potential energy efficiency standards, the Max Tech and Beyond project aims to answer these questions. The analysis attempts to consolidate, in one document, the energy savings potential and design characteristics of best-on-market products, best-engineered products (i.e., hypothetical products produced using best-on-market components and technologies), and emerging technologies in research & development. As defined here, emerging technologies are fundamentally new and are as yet unproven in the market, although laboratory studies and/or emerging niche applications offer persuasive evidence of major energy-savings potential. The term 'max tech' is used to describe both best-engineered and emerging technologies (whichever appears to offer larger savings). Few best-on-market products currently qualify as max tech, since few apply all available best practices and components. The

  5. Development of time-resolved laser-induced fluorescence spectroscopic technique for the analysis of biomolecules

    Directory of Open Access Journals (Sweden)

    Terzić M.

    2008-01-01

    Full Text Available Our developments of the time-resolved laser-induced fluorescence (TR-LIF detection system for biomolecules are presented. This system is based on the tunable (320 nm to 475 nm Nd:YAG laser pulses used to excite various biomolecules. The detection part is the Streak System for Fluorescence Lifetime Spectroscopy (Hamamatsu, Japan. The system consists of a C4334-01 streakscope, as a detector, DG 535 digital pulse/delay generator, C5094-S Spectrograph and HPD-TA System, as a temporal analyzer. The TR-LIF spectrometer is designed primarily to study the temperature and pressure effects on fluorescence behavior of biomolecules upon excitation with a single nanosecond pulse. The design of this system has capability to combine laser-induced breakdown (LIB with fluorescence, as well to study optodynamic behavior of fluorescence biomolecules.

  6. Magnetic GMI sensor for detection of biomolecules

    International Nuclear Information System (INIS)

    A magnetic sensor based on the giant magnetoimpedance (GMI) effect for the detection of biomolecules was made with a CoFeSiB amorphous magnetic microwire as sensing element. Using soft ferromagnetic cobalt microparticles and field sensitivities of the impedance of about 2.5%/A m-1 in the very low field region (less than 200 A m-1) at frequencies close to 10 MHz, a highly sensitive response was measured, appropriate for the detection of low biomolecule concentrations

  7. Fabrication and installation of the irradiation equipment design verification test facility

    Energy Technology Data Exchange (ETDEWEB)

    Cho, M. S.; Kang, Y. H.; Kim, B. G. and others

    2000-08-01

    The half-core model with the same configuration as the HANARO reactor, however which the sectional area of the core was cut down half, was developed to test the performance and improve the design of the capsules outside the reactor. The three different materials of aluminium, Zircalloy-4 and SUS304 are used in the HANARO reactor, however, only SUS304 material is used in the test facility because there's no need to consider the effect of neutrons and radiation on it. The 14 sight glasses are installed to view the inside flow and the vibration, and 17 flow receptacles are furnished so that the corresponding flow tubes will be fit in when the half core system will be equipped in the future. The leak tightness was confirmed through the hydraulic pressure test which has the different test pressures of 160kpa and 470kpa at upper and lower part. This test facility can be contributed to the design verification and the performance improvement through the capsule loading test, the hydraulic performance test, the vibration and the endurance test etc.. In addition, this facility can be used on the multi-purpose test such as the drop time test of SO/CA rod after the scheduled drop times, the vibration test of the HANARO fuel and the test of various tools for HANARO operation.

  8. An overview: biomolecules from microalgae for animal feed and aquaculture.

    Science.gov (United States)

    Yaakob, Zahira; Ali, Ehsan; Zainal, Afifi; Mohamad, Masita; Takriff, Mohd Sobri

    2014-12-01

    Despite being more popular for biofuel, microalgae have gained a lot of attention as a source of biomolecules and biomass for feed purposes. Algae farming can be established using land as well as sea and strategies can be designed in order to gain the products of specific interest in the optimal way. A general overview of the contributions of Algae to meet the requirements of nutrients in animal/aquaculture feed is presented in this study. In addition to its applications in animal/aquaculture feed, algae can produce a number of biomolecules including astaxanthin, lutein, beta-carotene, chlorophyll, phycobiliprotein, Polyunsaturated Fatty Acids (PUFAs), beta-1,3-glucan, and pharmaceutical and nutraceutical compounds which have been reviewed with respect to their commercial importance and current status. The review is further extended to highlight the adequate utilization of value added products in the feeds for livestock, poultry and aquaculture (with emphasis in shrimp farming).

  9. Recent advances in exploiting ionic liquids for biomolecules: Solubility, stability and applications.

    Science.gov (United States)

    Sivapragasam, Magaret; Moniruzzaman, Muhammad; Goto, Masahiro

    2016-08-01

    The technological utility of biomolecules (e.g. proteins, enzymes and DNA) can be significantly enhanced by combining them with ionic liquids (ILs) - potentially attractive "green" and "designer" solvents - rather than using in conventional organic solvents or water. In recent years, ILs have been used as solvents, cosolvents, and reagents for biocatalysis, biotransformation, protein preservation and stabilization, DNA solubilization and stabilization, and other biomolecule-based applications. Using ILs can dramatically enhance the structural and chemical stability of proteins, DNA, and enzymes. This article reviews the recent technological developments of ILs in protein-, enzyme-, and DNA-based applications. We discuss the different routes to increase biomolecule stability and activity in ILs, and the design of biomolecule-friendly ILs that can dissolve biomolecules with minimum alteration to their structure. This information will be helpful to design IL-based processes in biotechnology and the biological sciences that can serve as novel and selective processes for enzymatic reactions, protein and DNA stability, and other biomolecule-based applications. PMID:27312484

  10. WIPP conceptual design report. Addendum J. Support equipment in the high level waste facility of the Waste Isolation Pilot Plant

    International Nuclear Information System (INIS)

    The Aerojet Manufacturing Company (AMCO) received a contract in November 1976 to provide consulting services in assisting Holmes and Narver, Incorporated with the conceptual designs, cost estimates, and schedules of equipment used to handle waste casks, to decontaminate waste canisters and to overpack damaged or highly contaminated waste canisters for the Waste Isolation Pilot Plant (WIPP). Also, the layout of the hot cell in which canister handling, overpack and decontamination takes place was to be reviewed along with the time and motion study of the cell operations. This report has been prepared to present the results of the efforts and contains all technical and planning data developed during the program. The contents of this report are presented in three sections: (1) comments on the existing design criteria, equipment conceptual designs, hot cell design and time and motion studies of projected hot cell activities; (2) design descriptions of the equipment concepts and justification for varying from the existing concept (if a variation occurred). Drawings of each concept are provided in Appendix A. These design descriptions and drawings were used as the basis for the cost estimates; and (3) schedule projections and cost estimates for the equipment described in Section 2. Detail cost estimate backup data is provided in Appendix B

  11. Equipment Design and Cost Estimation for Small Modular Biomass Systems, Synthesis Gas Cleanup, and Oxygen Separation Equipment; Task 1: Cost Estimates of Small Modular Systems

    Energy Technology Data Exchange (ETDEWEB)

    Nexant Inc.

    2006-05-01

    This deliverable is the Final Report for Task 1, Cost Estimates of Small Modular Systems, as part of NREL Award ACO-5-44027, ''Equipment Design and Cost Estimation for Small Modular Biomass Systems, Synthesis Gas Cleanup and Oxygen Separation Equipment''. Subtask 1.1 looked into processes and technologies that have been commercially built at both large and small scales, with three technologies, Fluidized Catalytic Cracking (FCC) of refinery gas oil, Steam Methane Reforming (SMR) of Natural Gas, and Natural Gas Liquids (NGL) Expanders, chosen for further investigation. These technologies were chosen due to their applicability relative to other technologies being considered by NREL for future commercial applications, such as indirect gasification and fluidized bed tar cracking. Research in this subject is driven by an interest in the impact that scaling has on the cost and major process unit designs for commercial technologies. Conclusions from the evaluations performed could be applied to other technologies being considered for modular or skid-mounted applications.

  12. Design challenges for matrix assisted pulsed laser evaporation and infrared resonant laser evaporation equipment

    Science.gov (United States)

    Greer, James A.

    2011-11-01

    Since the development of the Matrix Assisted Pulsed Laser Evaporation (MAPLE) process by the Naval Research Laboratory (NRL) in the late 1990s, MAPLE has become an active area of research for the deposition of a variety of polymer, biological, and organic thin films. As is often the case with advancements in thin-film deposition techniques new technology sometimes evolves by making minor or major adjustments to existing deposition process equipment and techniques. This is usually the quickest and least expensive way to try out new ideas and to "push the envelope" in order to obtain new and unique scientific results as quickly as possible. This process of "tweaking" current equipment usually works to some degree, but once the new process is further refined overall designs for a new deposition tool based on the critical attributes of the new process typically help capitalize more fully on the all the salient features of the new and improved process. This certainly has been true for the MAPLE process. In fact the first MAPLE experiments the polymer/solvent matrix was mixed and poured into a copper holder held at LN2 temperature on a laboratory counter top. The holder was then quickly placed onto a LN2 cooled reservoir in a vacuum deposition chamber and placed in a vertical position on a LN2 cooled stage and pumped down as quickly as possible. If the sample was not placed into the chamber quickly enough the frozen matrix would melt and drip into the bottom of the chamber onto the chambers main gate valve making a bit of a mess. However, skilled and motivated scientists usually worked quickly enough to make this process work most of the time. The initial results from these experiments were encouraging and led to several publications which sparked considerable interest in this newly developed technique Clearly this approach provided the vision that MAPLE was a viable deposition process, but the equipment was not optimal for conducting MAPLE experiments on a regular basis

  13. Design guidelines for use of adhesives in hybrid microcircuits. [for electronic equipment in space applications

    Science.gov (United States)

    Caruso, S. V.; Perkins, K. L.; Licari, J. J.

    1973-01-01

    Although it is generally accepted that the use of adhesives in the assembly of hybrid microcircuits offers advantages over other bonding methods, there currently does not exist a set of guidelines for the selection of adhesives which will insure that hybrid microcircuits assembled with them will meet the long use-life, high-reliability requirements of electronic equipment for space applications. This study was directed to the identification of the properties of electrically insulative adhesives that potentially could cause problems in such an application, and to the development of evaluation tests to quantify these properties and thus form the basis for establishing suitable guidelines and, ultimately, specifications. Bond strength, outgassing after cure, and corrosivity were selected for detailed attention since they are considered to be especially critical. Introductory discussion includes enumeration and brief comments on the properties of adhesives considered to be important for the proposed application, a general review of polymeric types of adhesives, and identification of the major types of adhesives commercially available and specifically designed for microelectronic use. The specific tests developed to evaluate bond strength, outgassing after cure, and corrosivity are discussed in detail, and comparative results obtained for selected adhesives representative of the major types are given.

  14. Manual on safety aspects of the design and equipment of hot laboratories. 1981 ed

    International Nuclear Information System (INIS)

    This manual covers the general principles of planning and design of areas inside laboratories according to the varying potential radiation and contamination hazards; enclosures for radioactive material containment; viewing and lighting systems and various types of manipulators; transfer and transport of radioactive materials within the laboratories; air cleaning and ventilation systems, with particular reference to IAEA Safety Series No.17; techniques for controlling air pollution from the operation of nuclear facilities; various radioactive waste disposal systems; criticality control; fire protection; personnel monitoring, including changing-room monitoring and protective clothing; standardization and automation; and administrative controls. Although alpha, beta, gamma technologies have developed separately, equipment used in radioactive work is common to many operations. There is a step change in technology between work with uranium and plutonium and between work with plutonium and other transuranics; with plutonium one enters the field of alpha, beta, gamma technology. This manual reports the basic requirements and gives reference to more sophisticated techniques available. It is not concerned with work on a commercial scale. Other publications of interest in this context, for instance IAEA Safety Series No.39, are referenced for more detailed information.

  15. Design Frame of Equipment Operation Test Concept%装备作战试验概念设计框架

    Institute of Scientific and Technical Information of China (English)

    罗小明; 池建军; 周跃

    2012-01-01

    提出了装备作战试验目标、内容、流程和方法、组织指挥、评估的5维概念设计框架。从提高装备综合战技性能、确定装备编配运用原则、检验优化装备体系结构3个方面,明确了装备作战试验的目标定位;对装备作战适用性试验和装备作战效能试验2项主要内容进行了论释;提出了装备作战试验的组织实施流程,列出了外场实装、内场仿真、等效推算和一体化试验方法;构建了基于信息系统的装备作战试验组织指挥能力的构成框架;给出了装备作战试验评估的基本思路和主要步骤。可为装备作战试验顶层设计和创新研究提供新的手段。%The paper presents a 5-demensions concept design frame of equipment operation test, which ineludes the target, content, process & method, organization & command, and evaluation. It analyses the goal orientation of equipment operation test from three aspects of improving equipment synthetical tactics and technique performance, fixing on equipment arranging and managing principle, checking up and optimizing equipment system configuration. It explains two main contents of equipment operation applicability test and equipment operation efficiency test, advances the organization and execution process of equipment operation test, lists out the basic methods which include outfield installation method, infield simulation method, equivalent calculation method, integrative method. The equipment operation test organization and command capability structure frame is built based on information system, the equipment operation test evaluation basic thought and main steps are concluded, which provides new measure for equipment operation test top design and innovation research.

  16. Biomolecule-assisted route to prepare titania mesoporous hollow structures.

    Science.gov (United States)

    Ding, Shangjun; Wang, Yaoming; Hong, Zhanglian; Lü, Xujie; Wan, Dongyun; Huang, Fuqiang

    2011-10-01

    Amino acids, as a particularly important type of biomolecules, have been used as multifunctional templates to intelligently construct mesoporous TiO(2) hollow structures through a simple solvothermal reaction. The structure-directing behaviors of various amino acids were systematically investigated, and it was found that these biomolecules possess the general capability to assist mesoporous TiO(2) hollow-sphere formation. At the same time, the nanostructures of the obtained TiO(2) are highly dependent on the isoelectric points (pI) of amino acids. Their molecular-structure variations can lead to pI differences and significantly influence the final TiO(2) morphologies. Higher-pI amino acids (e.g., L-lysine and L-arginine) have better structure-directing abilities to generate nanosheet-assembled hollow spheres and yolk/shell structures. The specific morphologies and mesopore size of these novel hollow structures can also be tuned by adjusting the titanium precursor concentration. Heat treatment in air and vacuum was further conducted to transform the as-prepared structures to porous nanoparticle-assembled hollow TiO(2) and TiO(2)/carbon nanocomposites, which may be potentially applied in the fields of photocatalysts, dye-sensitized solar cells, and Li batteries. This study provides some enlightenment on the design of novel templates by taking advantage of biomolecules. PMID:21882272

  17. 搅拌设备设计专家系统%An expert system for mixing equipment process design

    Institute of Scientific and Technical Information of China (English)

    冯连芳; 王嘉骏; 顾雪萍; 王凯

    2001-01-01

    搅拌设备设计专家系统,采用人工智能技术与传统设计程序相结合的方法,实现从搅拌桨选型、过程设计、机械设计和经济分析评价,到最终机械绘图的全过程的智能化计算机辅助设计。此智能系统可为用户提供有关搅拌设备选型、设计和优化的系统指导和帮助。详细阐述了设计过程的多任务模型、系统接口设计和辅助功能模块。%The development of an expert system for mixing equipment selection, design and optimization (MIXiCAD) including agitator selection, process design, mechanical detailed design, technical- economics justification and mechanical drawing was addressed. The merging of artificial intelligent technology and conventional design program put mixing equipment design automatically into realities. This intelligent system could offer systematic assistance for mixing equipment design and evaluate in the early stage of agitator selection, as far as possible, get detailed mechanical drawing. The multi- task model of the design process, system interface and several important auxiliary function components were illustrated in detail.

  18. Reaction between protein radicals and other biomolecules

    DEFF Research Database (Denmark)

    Østdal, Henrik; Davies, Michael Jonathan; Andersen, Henrik J

    2002-01-01

    The present study investigates the reactivity of bovine serum albumin (BSA) radicals towards different biomolecules (urate, linoleic acid, and a polypeptide, poly(Glu-Ala-Tyr)). The BSA radical was formed at room temperature through a direct protein-to-protein radical transfer from H(2)O(2......)-activated immobilized horseradish peroxidase (im-HRP). Subsequently, each of the three different biomolecules was separately added to the BSA radicals, after removal of im-HRP by centrifugation. Electron spin resonance (ESR) spectroscopy showed that all three biomolecules quenched the BSA radicals....... Subsequent analysis showed a decrease in the concentration of urate upon reaction with the BSA radical, while the BSA radical in the presence of poly(Glu-Ala-Tyr) resulted in increased formation of the characteristic protein oxidation product, dityrosine. Reaction between the BSA radical and a linoleic acid...

  19. SECOND GENERATION EXPERIMENTAL EQUIPMENT DESIGN TO SUPPORT VOLOXIDATION TESTING AT INL

    International Nuclear Information System (INIS)

    Voloxidation is a potential head-end process used prior to aqueous or pyrochemical spent-oxide-fuel treatment. The spent oxide fuel is heated to an elevated temperature in oxygen or air to promote separation of the fuel from the cladding as well as volatize the fission products. The Idaho National Laboratory (INL) and the Korea Atomic Energy Research Institute (KAERI) have been collaborating on voloxidation research through a joint International Nuclear Energy Research Initiative (I-NERI). A new furnace and off-gas trapping system (OTS) with enhanced capability was necessary to perform further testing. The design criteria for the OTS were jointly agreed upon by INL and KAERI. First, the equipment must accommodate the use of spent nuclear fuel and be capable of operating in the Hot Fuel Examination Facility (HFEF) at the INL. This primarily means the furnace and OTS must be remotely operational and maintainable. The system requires special filters and distinctive temperature zones so that the fission products can be uniquely captured. The OTS must be sealed to maximize the amount of fission products captured. Finally, to accommodate the largest range of operating conditions, the OTS must be capable of handling high temperatures and various oxidizing environments. The constructed system utilizes a vertical split-tube furnace with four independently controlled zones. One zone is capable of reaching 1200 C to promote the release of volatile fission products. The three additional zones that capture fission products can be controlled to operate between 100-1100 C. A detailed description of the OTS will be presented as well as some initial background information on high temperature seal options

  20. Remote maintenance systems requirements are being developed to provide design guidelines for machine components, to define maintenance interfaces, and to quantify maintenance equipment and procedures needed

    International Nuclear Information System (INIS)

    Remote maintenance systems requirements are being developed to provide design guidelines for machine components, to define maintenance interfaces, and to quantify maintenance equipment and procedures needed

  1. Portable Kitchen Equipment Design Research%可携带式厨房设备设计研究

    Institute of Scientific and Technical Information of China (English)

    泮娇娇; 周晓江

    2013-01-01

    Life habits of university graduate groups is discussed and analyzed. From the aspects of different function to the design of portable kitchen equipment requirements to explore. Preliminary design of portable kitchen equipment are given, and the main study crowd portable kitchen design of research and discussion.%主要对大学刚毕业人群的生活习惯做了探讨和分析。从不同功能方面对可携带式厨房设备的设计要求作出探讨。对实现可携带式厨房设备作出初步构想,并且作了主要针对人群可携带式厨房设计研究的课题研究和探讨。

  2. Simple approach to study biomolecule adsorption in polymeric microfluidic channels

    Energy Technology Data Exchange (ETDEWEB)

    Gubala, Vladimir, E-mail: V.Gubala@kent.ac.uk [Biomedical Diagnostics Institute (BDI), National Centre for Sensor Research (NCSR), Dublin City University, Dublin 9 (Ireland); Medway School of Pharmacy, University of Kent, Central Avenue, Anson 120, Chatham Maritime, Kent ME4 4TB (United Kingdom); Siegrist, Jonathan; Monaghan, Ruairi; O' Reilly, Brian; Gandhiraman, Ram Prasad [Biomedical Diagnostics Institute (BDI), National Centre for Sensor Research (NCSR), Dublin City University, Dublin 9 (Ireland); Daniels, Stephen [Biomedical Diagnostics Institute (BDI), National Centre for Sensor Research (NCSR), Dublin City University, Dublin 9 (Ireland); National Centre for Plasma Science and Technology (NCPST), Dublin City University, Dublin 9 (Ireland); Williams, David E. [Biomedical Diagnostics Institute (BDI), National Centre for Sensor Research (NCSR), Dublin City University, Dublin 9 (Ireland); MacDiarmid Institute for Advanced Materials and Nanotechnology, School of Chemical Sciences, University of Auckland, Auckland 1142 (New Zealand); Ducree, Jens [Biomedical Diagnostics Institute (BDI), National Centre for Sensor Research (NCSR), Dublin City University, Dublin 9 (Ireland)

    2013-01-14

    Highlights: Black-Right-Pointing-Pointer A simple tool to assess biomolecule adsorption onto the surfaces of microchannels. Black-Right-Pointing-Pointer Development for dilution by surface-adsorption based depletion of protein samples. Black-Right-Pointing-Pointer It can easily be done using a readily available apparatus like a spin-coater. Black-Right-Pointing-Pointer The assessment tool is facile and quantitative. Black-Right-Pointing-Pointer Straightforward comparison of different surface chemistries. - Abstract: Herein a simple analytical method is presented for the characterization of biomolecule adsorption on cyclo olefin polymer (COP, trade name: Zeonor{sup Registered-Sign }) substrates which are widely used in microfluidic lab-on-a-chip devices. These Zeonor{sup Registered-Sign} substrates do not possess native functional groups for specific reactions with biomolecules. Therefore, depending on the application, such substrates must be functionalized by surface chemistry methods to either enhance or suppress biomolecular adsorption. This work demonstrates a microfluidic method for evaluating the adsorption of antibodies and oligonucleotides surfaces. The method uses centrifugal microfluidic flow-through chips and can easily be implemented using common equipment such as a spin coater. The working principle is very simple. The user adds 40 L of the solution containing the sample to the starting side of a microfluidic channel, where it is moved through by centrifugal force. Some molecules are adsorbed in the channel. The sample is then collected at the other end in a small reservoir and the biomolecule concentration is measured. As a pilot application, we characterized the adsorption of goat anti-human IgG and a 20-mer DNA on Zeonor{sup Registered-Sign }, and on three types of functionalized Zeonor: 3-aminopropyltriethoxysilane (APTES) modified surface with mainly positive charge, negatively charged surface with immobilized bovine serum albumin (BSA), and

  3. Tuneable graphene nanopores for single biomolecule detection

    Science.gov (United States)

    Al-Dirini, Feras; Mohammed, Mahmood A.; Hossain, Md Sharafat; Hossain, Faruque M.; Nirmalathas, Ampalavanapillai; Skafidas, Efstratios

    2016-05-01

    Solid-state nanopores are promising candidates for next generation DNA and protein sequencing. However, once fabricated, such devices lack tuneability, which greatly restricts their biosensing capabilities. Here we propose a new class of solid-state graphene-based nanopore devices that exhibit a unique capability of self-tuneability, which is used to control their conductance, tuning it to levels comparable to the changes caused by the translocation of a single biomolecule, and hence, enabling high detection sensitivities. Our presented quantum simulation results suggest that the smallest amino acid, glycine, when present in water and in an aqueous saline solution can be detected with high sensitivity, up to a 90% change in conductance. Our results also suggest that passivating the device with nitrogen, making it an n-type device, greatly enhances its sensitivity, and makes it highly sensitive to not only the translocation of a single biomolecule, but more interestingly to intramolecular electrostatics within the biomolecule. Sensitive detection of the carboxyl group within the glycine molecule, which carries a charge equivalent to a single electron, is achieved with a conductance change that reaches as high as 99% when present in an aqueous saline solution. The presented findings suggest that tuneable graphene nanopores, with their capability of probing intramolecular electrostatics, could pave the way towards a new generation of single biomolecule detection devices.

  4. Immobilizing Biomolecules Near the Diffraction Limit

    DEFF Research Database (Denmark)

    Skovsen, Esben; Petersen, Maria Teresa Neves; Gennaro, Ane Kold Di;

    2009-01-01

    Our group has previously shown that biomolecules containing disulfide bridges in close proximity to aromatic residues can be immobilized, through covalent bonds, onto thiol derivatized surfaces upon UV excitation of the aromatic residue(s). We have also previously shown that our new technology ca...

  5. A Multidisciplinary, Open Access Platform for Research on Biomolecules

    Directory of Open Access Journals (Sweden)

    Jürg Bähler

    2011-08-01

    Full Text Available I am pleased to introduce Biomolecules, a new journal to report on all aspects of science that focuses on biologically derived substances, from small molecules to complex polymers. Some examples are lipids, carbohydrates, vitamins, hormones, amino acids, nucleotides, peptides, RNA and polysaccharides, but this list is far from exhaustive. Research on biomolecules encompasses multiple fascinating questions. How are biomolecules synthesized and modified? What are their structures and interactions with other biomolecules? How do biomolecules function in biological processes, at the level of organelles, cells, organs, organisms, or even ecosystems? How do biomolecules affect either the organism that produces them or other organisms of the same or different species? How are biomolecules shaped by evolution, and how in turn do they affect cellular phenotypes? What is the systems-level contribution of biomolecules to biological function?

  6. Ionic strength independence of charge distributions in solvation of biomolecules

    OpenAIRE

    Virtanen, J. J.; Sosnick, T. R.; Freed, K. F.

    2014-01-01

    Electrostatic forces enormously impact the structure, interactions, and function of biomolecules. We perform all-atom molecular dynamics simulations for 5 proteins and 5 RNAs to determine the dependence on ionic strength of the ion and water charge distributions surrounding the biomolecules, as well as the contributions of ions to the electrostatic free energy of interaction between the biomolecule and the surrounding salt solution (for a total of 40 different biomolecule/solvent combinations...

  7. Impact of Mars sand on dust on the design of space suits and life support equipment: A technology assessment

    Science.gov (United States)

    Simonds, Charles H.

    1991-01-01

    Space suits and life support equipment will come in intimate contact with Martian soil as aerosols, wind blown particles and material thrown up by men and equipment on the Martian surface. For purposes of this discussion the soil is assumed to consist of a mixture of cominuted feldspar, pyroxene, olivine, quartz, titanomagnetite and other anhydrous and hydrous iron bearing oxides, clay minerals, scapolite and water soluble chlorides and sulfates. The soil may have photoactivated surfaces that acts as a strong oxidizer with behavior similar to hydrogen peroxide. The existing data about the Mars soil suggests that the dust and sand will require designs analogous to those uses on equipment exposed to salty air and blowing sand and dust. The major design challenges are in developing high performance radiators which can be cleaned after each EVA without degradation, designing seals that are readily cleaned and possibly in selecting materials which will not be degraded by any strong oxidants in the soil. The magnitude of the dust filtration challenge needs careful evaluation in terms of the trade off between fine-particle dust filters with low pressure drop that are either physically large and heavy, like filter baghouses require frequent replacement of filter elements, of low volume high pressure thus power consumption approaches, or washable filters. In the latter, filter elements are cleaned with water, as could the outsides of the space suits in the airlock.

  8. New and improved designs of surface mining equipment and machine parts for efficient mining and haulage in the mining industry and in soil engineering

    Energy Technology Data Exchange (ETDEWEB)

    Kluge, H.; Reinel, H. (VEB SMK TAKRAF (German Democratic Republic). Georgi-Dimitroff-Werk)

    1989-01-01

    Explains specifications and design of mining equipment series produced by the TAKRAF manufacturer, GDR for coal and mineral surface mines. Equipment includes SRs bucket wheel excavators, ERs bucket chain excavators and BRs mobile transfer conveyors. Various photographs are provided. Small sized equipment is available for selective mining of sections in larger mines as well as for operation in small mines with mine production of 150 to 300 thousand m{sup 3}. Another focus is equipment for direct spoil overcast by a combination of bucket wheel or bucket chain excavator, mobile conveyor and spoil spreader. Recently developed equipment, its production capacity and size are presented.

  9. Interaction and educational design of mobile equipment for crisis management training

    DEFF Research Database (Denmark)

    Ørngreen, Rikke

    2011-01-01

    As researchers and designers of crisis management training in mobile learning settings, we need to consider ways in which principles of educational design and interaction design can co-exist, in order to reach a higher quality of the analysis and design process. The paper is an input to this disc......As researchers and designers of crisis management training in mobile learning settings, we need to consider ways in which principles of educational design and interaction design can co-exist, in order to reach a higher quality of the analysis and design process. The paper is an input...

  10. Design and Application of an Expert System for Equipment Maintenance and Forecast

    Institute of Scientific and Technical Information of China (English)

    WANG Jian; PAN Kai-long; SHEN Yun-feng; LI Jie

    2007-01-01

    The maintenance and forecast expert system of equipment based on Artificial Neural Network is composed of control, measure, failure forecast, execution, data processing module and database. The data processing module obtains the change of the controlled objects′ structure and parameters, then takes correspondent measures according to the examination and diagnosis information. The failure forecast module finds the control system fault, separates the fault symptom location, tells the fault kind, estimates the magnitude and time of the fault, and finally makes evaluation and decision.

  11. Solar Equipment

    Science.gov (United States)

    1983-01-01

    A medical refrigeration and a water pump both powered by solar cells that convert sunlight directly into electricity are among the line of solar powered equipment manufactured by IUS (Independent Utility Systems) for use in areas where conventional power is not available. IUS benefited from NASA technology incorporated in the solar panel design and from assistance provided by Kerr Industrial Applications Center.

  12. Quantum dots and their interaction with biomolecules

    OpenAIRE

    Stanisavljević, Maja

    2015-01-01

    In this study CdTe QDs were synthetized via microwave irradiation method. Further they have been modified for purposes of their interaction with biomolecules using different conjugation approaches. Applied conjugation chemistries were non-specific interaction, streptavidin-biotin affinity. Glutathione modified CdTe QDs of 2 nm size were capable of non-specific interaction with major groove of DNA, while streptavidin modified CdTe QDs served as specific linker for biotinylated oligonucleotides...

  13. Immobilizing Biomolecules Near the Diffraction Limit

    DEFF Research Database (Denmark)

    Skovsen, Esben; Neves-Petersen, Maria Teresa; Kold, Ane;

    2009-01-01

    Our group has previously shown that biomolecules containing disulfide bridges in close proximity to aromatic residues can be immobilized, through covalent bonds, onto thiol derivatized surfaces upon UV excitation of the aromatic residue(s). We have also previously shown that our new technology ca...... a substrate, which can be generated by a UV diffraction pattern. Such patterns can have sub-micron feature sizes and could therefore be of great relevance for present and future nanotechnological applications....

  14. Of Tangerines, Asparagus, and Nonprotein Biomolecules.

    Science.gov (United States)

    2016-05-19

    Every month the editors of Cell Chemical Biology bring you highlights of the most recent chemical biology literature. Our May 2016 selection includes a new method for labeling and visualizing nonprotein biomolecules using electron microscopy; a small molecule, originally found in tangerine peel, that regulates our circadian clock and helps with some of the metabolic pathologies associated with circadian rhythms; and a finding that asparagine is used as an amino acid exchanger in tumor cells. PMID:27203369

  15. Safety Design of Military Electronic Equipment%军用电子设备安全性设计

    Institute of Scientific and Technical Information of China (English)

    生建友

    2013-01-01

    Safety is attracting more and more attention as an important part of quality characteristics for weapons and equipment. Due to the more complex composition structure,the higher automatic level and the intercepted probability of electromagnetic wave produced in operation,the possibility of safety accidents occurrence on mili-tary electronic equipment is becoming higher and higher. This paper introduces the safety concept and empha-sizes the functions of safety.According to the requirements of GJB and the practice experience of military elec-tronic equipment,it analyzes the qualitative and quantitative requirements for safety design,proposes the main contents,finally discusses the concrete measures of safety design for personnel,equipment and electromagnetic information for military electronic equipment in detail. The methods presented herein can be useful for those who are engaged in designing,managing and maintaining in this field.%  安全性作为武器装备质量特性中的一项重要内容越来越受到人们的重视。由于组成结构越来越复杂、自动化程度越来越高以及工作时产生的电磁波可能被截获等原因,军用电子设备发生安全事故的可能性越来越大。介绍了安全性的定义,强调了安全性的作用。结合国军标要求和军用电子设备的使用实际,分析了设备安全性设计的定性、定量要求,提出了安全性设计的主要内容,详细讨论了军用电子设备人员、设备的安全性设计和电磁信息安全设计的具体措施,可供该领域从事设计、管理和维修的人员借鉴。

  16. The design of an energy harvesting device for prolonging the working time of DC equipment

    Science.gov (United States)

    Wen, Yayuan; Deng, Huaxia; Zhang, Jin; Yu, Liandong

    2016-01-01

    Energy harvesting (EH) derives from the idea of converting the ambient energy into electric energy, which can solve the problem of DC supply for some electronic equipment. PZT is a typical piezoelectric material of inorganic, which has been developed as EH devices to transfer ambient vibration energy into electric energy. However, these PZT devices require relatively violent excitation, and easy to be fatigue fracture under the resonance condition. In this paper, PVDF, which is a kind of soft piezoelectric polymer, is adopted for developing transducer. The PVDF devices are flexible and have longer life time than PZT devices under the harmonic environment. The EH researches are mainly focused on the development of energy transfer efficiency either by the mechanical structure of transducer or the improvement of circuit. However, the practicality and stability of the EH devices are important in the practical engineering applications. In this paper, a charge amplifier is introduced in the circuit in order to guarantee the stability of the battery charging under small ambient vibration conditions. The model of the mechanical structure of PVDF and the electric performance of circuit are developed. The experimental results and simulation show that the stability of battery charging is improved and the working time of DC equipment is prolonged.

  17. The design of equipment for optical power measurement in FSO link beam cross-section

    Science.gov (United States)

    Latal, Jan; David, Tomas; Wilfert, Otakar; Kolka, Zdenek; Koudelka, Petr; Hanacek, Frantisek; Vitasek, Jan; Siska, Petr; Skapa, Jan; Vasinek, Vladimir

    2012-06-01

    The free space optical links have found their major application in today's technological society. The demand for quality broadband is a must for all types of end users in these times. Because of the large jamming from wireless radio networks in non-licensed ISM bands, the free space optical links provide bridging of some densely populated urban areas. Their advantage is the high transmission rate for relatively long distances. However, the disadvantage is the dependence of free space optical links on atmospheric influences. Aired collimated optical beam passes through the atmospheric transmission environment and by its influence cause the deformation of the optical beam. Author's team decided to construct a special measuring device for measurement of optical power in FSO link beam cross-section. The equipment is mobile and can be rearranged and adjust according to the given location and placement of the FSO link at any time. The article describes the individual structural elements of the measuring equipment, its controlling and application for evaluation and adjustment of measuring steps. The graphs from optical power measurements in the beam cross-section of professional FSO links are presented at the end.

  18. An aptamer-functionalized chemomechanically modulated biomolecule catch-and-release system

    Science.gov (United States)

    Shastri, Ankita; McGregor, Lynn M.; Liu, Ya; Harris, Valerie; Nan, Hanqing; Mujica, Maritza; Vasquez, Yolanda; Bhattacharya, Amitabh; Ma, Yongting; Aizenberg, Michael; Kuksenok, Olga; Balazs, Anna C.; Aizenberg, Joanna; He, Ximin

    2015-05-01

    The efficient extraction of (bio)molecules from fluid mixtures is vital for applications ranging from target characterization in (bio)chemistry to environmental analysis and biomedical diagnostics. Inspired by biological processes that seamlessly synchronize the capture, transport and release of biomolecules, we designed a robust chemomechanical sorting system capable of the concerted catch and release of target biomolecules from a solution mixture. The hybrid system is composed of target-specific, reversible binding sites attached to microscopic fins embedded in a responsive hydrogel that moves the cargo between two chemically distinct environments. To demonstrate the utility of the system, we focus on the effective separation of thrombin by synchronizing the pH-dependent binding strength of a thrombin-specific aptamer with volume changes of the pH-responsive hydrogel in a biphasic microfluidic regime, and show a non-destructive separation that has a quantitative sorting efficiency, as well as the system's stability and amenability to multiple solution recycling.

  19. A Study on Design of Portable Communication Equipment%一种新型便携式通信设备设计方法的研究

    Institute of Scientific and Technical Information of China (English)

    蔡海兴

    2012-01-01

    A new design approach about portable communication equipment has been introduced based on character of portable communication equipment and development of some communication equipment. Firstly, the preliminary design of portable communication equipment is presented. The paper discusses structure design, environmental adaptability design, EMC design and so on.%根据便携式通信设备的特殊要求,结合某携行通信设备的研制,本文提出了一种新型便携式通信设备的设计思路和方法。首先给出便携式通信设备总体设计要求,然后从结构设计、环境适应性设计和EMC设计等多方面展开讨论。

  20. Immobilization of Biomolecules on Poly(vinyldimethylazlactone)-containing Surface Scaffolds

    Energy Technology Data Exchange (ETDEWEB)

    Barrninger, Joshua [Clemson University; Messman, Jamie M [ORNL; Banaszak, Abigail [Clemson University; Meyer III, Harry M [ORNL; Kilbey, II, S Michael [ORNL

    2009-01-01

    We describe the successful development of a procedure for the step-by-step formation of a reactive, multi-layer polymer scaffold incorporating polymers based on 2-vinyl-4,4-dimethylazlactone (VDMA) on a silicon wafer and the characterization of these materials. Also discussed is the development of a procedure for the non-site specific attachment of a biomolecule to the modified silicon wafer, including scaffolds modified via drop-on-demand (DOD) inkjet printing. VDMA-based polymers were used because of their hydrolytic stability and ability of the pendant azlactone rings to form stable covalent bonds with primary amines without byproducts via nucleophilic addition. This reaction proceeds without a catalyst and at room temperature, yielding a stable amide linkage, which adds to the ease of construction expected when using VDMA-based polymers. DOD inkjet printing was explored as an interesting method for creating surfaces with one or more patterns of biomolecules, because of the flexibility and ease in pattern design.

  1. 电子设备的接地和接地设计%Ground and Ground Design for Electronic Equipment

    Institute of Scientific and Technical Information of China (English)

    丁小东

    2001-01-01

    从电子设备的安全性和可靠性出发,论述了接地的重要性,并从接地类型、地线作用、接地设计等几方面介绍了有关接地技术的理论及应用。%This essay from electronic equipment of safe and reliability Start, Expound ground of significant, And from ground trpy. ground Line action. Design for ground etc. Servile aspects to introduce have Ground technique of basic knowledge. Basic theory and basic put to use.

  2. Erosion of wind turbine blade coatings - Design and analysis of jet-based laboratory equipment for performance evaluation

    DEFF Research Database (Denmark)

    Zhang, Shizhong; Dam-Johansen, Kim; Nørkjær, Sten;

    2015-01-01

    of the blades in such equipment. To reduce expensive blade maintenance repairs and to avoid out-of-service periods, energy-absorbing blade coatings are required to protect rotor blades from rain erosion. In this work we describe the design, construction and evaluation of a laboratory setup for fast screening...... of up to 22 coating samples that is based on water jet slugs. Our objective is to study the effect of the parameters involved in the rain erosion process and to correlate our experimental results with data obtained with the complex and expensive whirling arm rig, which has become the industry standard...

  3. Chitosan membrane development and design of equipment for the removal of heavy metals from water

    International Nuclear Information System (INIS)

    A filtration technique has compared with 1,75% m/v chitosan membranes, crosslinked with glutaraldehyde (0,08% m/v) and without cross link, to quantify the removal capacity of chromium, copper and cadmium ions of model solutions. In addition, a simple and low cost equipment was developed to use with prepared membranes. The main goal has been to use biodegradable materials for removing heavy metals from water, through a low energy consumption, cheap, and applicable to specific problems. Two data sheets were prepared for the membranes and was found that chromium was the metal with the highest removal from water, by using a crosslinked membrane. Metal adsorption was best adjusted to the Freundlich isotherm model, better than Langmuir isotherm model. However, no correlation has been found between pore size of the membranes and crosslinking degree. (author)

  4. Progress of R and D and design of blanket remote handling equipment for ITER

    International Nuclear Information System (INIS)

    The design of in-vessel transporter (IVT) including vehicle manipulator has been updated according to the design changes such as blanket segmentation and structure, taking account of the interface between modules and vehicle manipulator. In particular, the updated design of the vehicle manipulator and rail has been carried out because of collision avoidance between modules and vehicle manipulator. According to the updated design, the vehicle manipulator has been reduced by about 30% in weight, compared with the reference design. In parallel with design activities, the R and D to clarify the specifications of the IVT design in detail is also performed, i.e., simulation system to provide the visual information during maintenance, dry lubricant to prevent the lubricant oil from spreading in the vacuum vessel (VV). The rail connection and cable handling in the transfer cask, which are critical issues for IVT system, are under preparation of the demonstration tests to finalize the design of the IVT system. Connection of the rail joint and cable handling test facilities are planned and under fabrication now. These test facility will be installed by the end of March 2008, and the performance tests will be carried out from April 2008

  5. Design of equipment for microwave sterilization of food particulates. Memorandum report

    Energy Technology Data Exchange (ETDEWEB)

    Metaxas, A.C.

    1976-07-01

    The memorandum considers the design of a resonant microwave cavity, operating in the TMsub11(10) mode, for sterilization of liquid foodstuffs or particulates in gravy. The overall design and matching is considered in detail. Preliminary tests have been performed to study the uniformity of heating and optimization of the cavity design. Temperature differences within the cavity of up to 7% of the mean increment were found which may be high for some applications. The cavity utilization efficiency was of the order of 90% and very insensitive to changes in process parameters.

  6. Research cooperation project on environmentally friendly technology for highly efficient mineral resources extraction and treatment. Detail design for pilot plant (Purchased equipment)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    The paper prepared plans of the purchased equipment in the detailed design of a pilot plant in the joint research project on the environmental protection technology for highly efficient mineral resource extraction and treatment. (NEDO)

  7. 自动豆干切割设备的设计%Design of Automatic Cutting Dried Tofu Equipment

    Institute of Scientific and Technical Information of China (English)

    沈金龙; 李向坤

    2015-01-01

    为了提高企业生产效率实现切割生产的自动化,设计了一种基于可编程逻辑控制器(PLC)的豆干切割设备.通过分析豆干切割要求以及现有生产工艺,利用步进电机作为驱动,提出了工作台分层控制和刀片竖切的方法.设备满足生产要求,实现了豆干的双向自动切割.这种工作台分层控制双向切割软体食品的方法,对通用食品切割设备的设计具有借鉴意义.%In order to improve production efficiency and realize the automation of cutting production,it designs cutting dried tofu equipment based on programmable logic control er (PLC).Through the analysis of the cutting dried tofu requirements and existing production process,using stepping motor as a driver,it designs the method of workbench layered control and vertical cutting blades.The equipment met the production requirements,realized the two-direction automatic cutting dried tofu.

  8. Design and adaptation of miniaturized electrochemical devices integrating carbon nanotube-based sensors to commercial CE equipment.

    Science.gov (United States)

    Arribas, Alberto Sánchez; Moreno, Mónica; Bermejo, Esperanza; Angeles Lorenzo, M; Zapardiel, Antonio; Chicharro, Manuel

    2009-10-01

    The design of new electrochemical devices integrating carbon nanotube sensors and their adaptation to commercial CE equipments are described. One of these designs was made for using commercial screen-printed electrodes, whereas the second was projected for coupling commercial glassy carbon electrodes. The electrochemical characterization of these devices revealed that their hydrodynamic behaviour is strongly influenced by the electrode modification with multi-wall carbon nanotubes that provided faster and/or more sensitive signals. The analytical applicability of these devices was illustrated for the CZE separation of chlorinated phenols and the MEKC separation of endocrine disruptors, where the use of carbon nanotube sensors has proved to be advantageous when compared with unmodified ones, with good electrocatalytic properties combined with acceptable background currents and a remarkable resistance to passivation.

  9. Thermal design of a fully equipped solar-powered desert home

    KAUST Repository

    Serag-Eldin, M.A.

    2010-03-01

    The paper presents a conceptual design and thermodynamic analysis of a solar-powered desert home. The home is airconditioned and provides all modern comforts and facilities. Electrical power, which drives the entire energy system, is generated by roof mounted photovoltaic modules. A detailed dynamic heat transfer analysis is conducted for the building envelope, coupled with a solar radiation model. A dynamic heat balance for a typical Middle-Eastern desert site, reveals that indeed such a design is feasible with present day technology; and should be even more attractive with future advances in technology.

  10. Porous solid ion exchange wafer for immobilizing biomolecules

    Science.gov (United States)

    Arora, Michelle B.; Hestekin, Jamie A.; Lin, YuPo J.; St. Martin, Edward J.; Snyder, Seth W.

    2007-12-11

    A porous solid ion exchange wafer having a combination of a biomolecule capture-resin and an ion-exchange resin forming a charged capture resin within said wafer. Also disclosed is a porous solid ion exchange wafer having a combination of a biomolecule capture-resin and an ion-exchange resin forming a charged capture resin within said wafer containing a biomolecule with a tag. A separate bioreactor is also disclosed incorporating the wafer described above.

  11. Teaching Computer-Aided Design of Fluid Flow and Heat Transfer Engineering Equipment.

    Science.gov (United States)

    Gosman, A. D.; And Others

    1979-01-01

    Describes a teaching program for fluid mechanics and heat transfer which contains both computer aided learning (CAL) and computer aided design (CAD) components and argues that the understanding of the physical and numerical modeling taught in the CAL course is essential to the proper implementation of CAD. (Author/CMV)

  12. Interfacial water thickness at inorganic nanoconstructs and biomolecules: Size matters

    Science.gov (United States)

    Cardellini, Annalisa; Fasano, Matteo; Chiavazzo, Eliodoro; Asinari, Pietro

    2016-04-01

    Water molecules in the proximity of solid nanostructures influence both the overall properties of liquid and the structure and functionality of solid particles. The study of water dynamics at solid-liquid interfaces has strong implications in energy, environmental and biomedical fields. This article focuses on the hydration layer properties in the proximity of Carbon Nanotubes (CNTs) and biomolecules (proteins, polypeptides and amino acids). Here we show a quantitative relation between the solid surface extension and the characteristic length of water nanolayer (δ), which is confined at solid-liquid interfaces. Specifically, the size dependence is attributed to the limited superposition of nonbonded interactions in case of small molecules. These results may facilitate the design of novel energy or biomedical colloidal nanosuspensions, and a more fundamental understanding of biomolecular processes influenced by nanoscale water dynamics.

  13. Design and development of electric vehicle charging station equipped with RFID

    Science.gov (United States)

    Panatarani, C.; Murtaddo, D.; Maulana, D. W.; Irawan, S.; Joni, I. M.

    2016-02-01

    This paper reports the development of electric charging station from distributed renewable for electric vehicle (EV). This designed refer to the input voltage standard of IEC 61851, plugs features of IEC 62196 and standard communication of ISO 15118. The developed electric charging station used microcontroller ATMEGA8535 and RFID as controller and identifier of the EV users, respectively. The charging station successfully developed as desired features for electric vehicle from renewable energy resources grid with solar panel, wind power and batteries storage.

  14. Climate design of vegetable oil fuels for agricultural equipment; Klimadesign von Pflanzenoelkraftstoffen fuer landwirtschaftliche Maschinen

    Energy Technology Data Exchange (ETDEWEB)

    Stoehr, Michael [B.A.U.M. Consult GmbH, Muenchen (Germany). International and Energy Projects; Pickel, Peter [John Deere European Technology Innovation Center, Kaiserslautern (Germany)

    2012-07-01

    The use of biofuels in agricultural machinery is an option for complying with climate protection requirements that are presently discussed to be placed on manufacturers of mobile off-road machinery by the European Commission. A mathematical model has been developed that allows calculating greenhouse gas emissions (GHGE) of biofuels for complex production paths in a straightforward, transparent manner and in pattern with the EU's Fuel Quality Directive (FQD). Therewith it has been shown that both rape seed and camelina sativa oil fuels can save more than 60 % GHGE. Key parameters have been identified and rules for a climate design of vegetable oil fuels have been formulated. (orig.)

  15. a New Design for Diamond Window Equipped Paris-Edinburgh — First Tests and Results

    Science.gov (United States)

    Burchard, M.; Glasmacher, U. A.; Dedera, S.; Trautmann, C.

    2012-12-01

    High pressure cells of the Paris-Edinburgh type are important tools for experimental high pressure studies in material science. Although these cells were originally developed for use in neutron diffraction, today they are also applied in alternative experimental high pressure fields. Their main advantages are their small construction size, limited weight and the relative high reachable pressures with a maximized sample volume. The small construction size also results in very good cost efficiency. The major drawback of these cells is that due to their simple squeezer geometry pressure extrapolations are nearly impossible and, hence, the use of internal standard is mandatory. Consequently, the normal use of Paris-Edinburgh cells is mostly limited to experiments with neutron or synchrotron radiation, during which pressure and temperature are determined by using an internal diffraction standard. To overcome this problem, tone may combine the advantages of diamond anvil cells with those of Paris-Edinburgh-cells by integrating diamond windows into the upper and / or the lower anvil. With such a cell it is possible to retrieve pressure and / or temperature data by measuring the shift of Raman bands or fluorescence lines by spectroscopic methods. Several attempts have been made to build such a cell ([1] and Klotz pers. communication) using different window materials. Until now no final setup has been published. We present a new Paris-Edinburgh cell design especially constructed for use within high energy relativistic heavy ion radiation experiments. This design uses conventional diamond anvils as spectroscopic windows in conjunction with specially designed hardened steel anvils. We have performed first feasibility studies up to 2.5 GPa with a standard Raman spectrometer using a special adapted Raman glass fiber probe. We present results of several mechanical test runs and one experiment with relativistic heavy ion radiation at the GSI Helmholtzzentrum f

  16. Designing and improving boiler equipment for efficient utilization of coals from Ekibastuz deposit

    Energy Technology Data Exchange (ETDEWEB)

    Ovchar, V.G.; Sotnikov, I.A.; Aizen, Kh.K.; Petrov, E.V.

    1981-06-01

    Ekibastuz coal has a low moisture content (9-6%) but a high ash content (38-43%) and has the combustion heat of 17.2-16.6 MJ/kg. In future, however, coals with the combustion heat of 14.4-12.6 MJ/kg and ash content of 53-55% will be supplied to power plants. Research on improving the design of boilers fired with Ekibastuz coal has shown that the serially produced boiler type P-57 may be rebuilt to burn Ekibastuz coal with a high ash content.

  17. Demonstration Plant Equipment Design and Scale-Up from Pilot Plant of a Leaching and Solvent Extraction Process

    Directory of Open Access Journals (Sweden)

    Fátima Arroyo

    2015-05-01

    Full Text Available Germanium recovery from coal fly ash by hydrometallurgical procedures was studied at the pilot scale (5 kg of fly ash/h. Results were used to design the equipment of a demonstration-sized plant (200 kg of fly ash/h. The process is based on hydrometallurgical operations: firstly a germanium extraction from fly ash by leaching and a consequent Ge separation from the other elements present in the solution by solvent extraction procedures. Based on the experimental results, mass balances and McCabe-Thiele diagrams were applied to determine the number of steps of the solvent extraction stage. Different arrangements have been studied and a countercurrent process with three steps in extraction and six steps in elution was defined. A residence time of 5 min was fixed in both the extraction and elution stages. Volumetric ratios in extraction and stripping were: aqueous phase/organic phase = 5 and organic phase/stripping phase = 5, so a concentration factor of 25 is achieved. Mixers and decanters were completely defined. The maximum extracted and eluted germanium was estimated and a global efficiency of 94% was achieved. The cost-effectiveness of the equipment was estimated using the Lang factors.

  18. Electrical insulation design and evaluation of 60 kV prototype condenser cone bushing for the superconducting equipment

    International Nuclear Information System (INIS)

    Highlights: •The optimum design of condenser cone cryogenic bushing was investigated. •Multi-layer aluminum foils in the bushing insulation body was designed and analyzed. •The optimum electric field distribution was selected by simulation. •The 60 kV FRP condenser cone cryogenic bushing was fabricated and tested. •BIL test corresponding to IEC 60137 was successfully performed for the bushing. -- Abstract: A cryogenic bushing is an essential component to be developed for commercial applications of high voltage (HV) superconducting devices. Due to the steep temperature gradient of the ambient of cryogenic bushing, general gas bushing adopting SF6 gas as an insulating media could not be directly used due to the freezing of SF6 gas. Therefore, condenser type bushing with special material considering cryogenic environment would be better choice for superconducting equipment. Considering these circumstance, we focused on the design of condenser bushing made of fiber reinforced plastic (FRP). In case of the design of the condenser bushing, it is very important to reduce the electric field intensification on the mounted flange part of the cryostat, which is the most vulnerable part of bushings. In this paper, design factors of cryogenic bushing were analyzed, and finally 60 kV condenser bushing was fabricated and tested. In order to achieve optimal electric field configuration, the configuration of condenser cone was determined using 2D electric field simulation results. Based on the experimental and the analytical works, 60 kV FRP condenser bushing was fabricated. Finally, the fabricated condenser bushing has been tested by applying lightning impulse and AC overvoltage test. From the test results, it was possible to get satisfactory results which confirm the design of cryogenic bushing in cryogenic environment

  19. Physical Mechanisms of Crystal Growth Modification by Biomolecules

    Science.gov (United States)

    De Yoreo, James J.

    2010-07-01

    During the process of biomineralization, living organisms use macromolecules to direct the nucleation and growth of a variety of inorganic materials. Because biomineral structures exhibit complex topologies, hierarchical design, and unique materials properties, an understanding of the underlying mechanisms of biomolecular controls over mineral growth presents an opportunity to develop new strategies towards synthesis of novel materials for applications across a wide range of technologies. Herein the results from a combination of in situ atomic force microscopy (AFM) and molecular modeling (MM) studies to investigate the effect of specific interactions between carboxylate-rich biomolecules and atomic steps on calcium carbonate and calcium oxalate crystal surfaces during the growth are reviewed. The results show how the stereochemical relationships between additive and atomic step leads to modifications of crystal shape. In some cases, the inhibitory effects of strong binders are well-explained by a model of growth inhibition based on the classic Cabrera-Vermilyea theory, but updated to take into account the particular nature of biomolecular adsorption dynamics. The consequences include a positive feedback between peptide adsorption and step inhibition that results in bistable growth with rapid switching from fast to near-zero growth rates for very small changes in supersaturation. The phenomenon of biomolecule-induced growth acceleration is also reviewed and shown to be common to both the oxalate and carbonate systems. The source of acceleration is related to the activation barrier for solute attachment to steps. Finally, experimental and theoretical results are presented that suggest most biomineral phases can not be described by conventional models in which kink formation due to thermal fluctuations at step edges is rapid enough to ensure the availability of kinks. Instead, growth is kink-limited. As a consequence, biomolecule-step interactions cannot be

  20. Design of lubricating equipment of stud hole's threads of reactor pressure vessel

    International Nuclear Information System (INIS)

    It is determined that lubrication method of reactor pressure vessel (RPV) stud hole's thread is brushing lubrication by flow test of N5000 grease. The basic requirements of RPV stud hole's thread lubrication are all-surface and uniformity of greasing. The RPV stud hole lubricating machine is mainly composed of control panel, cable hanging device, automatic trolley and lubricating device. The lubricating device is the key part of RPV stud hole lubricating machine, therefore, the structure and principle of lubricating device are described. Besides, its operating principle, technical characteristics and design features are briefly described. During refuelling and repairing of No.1 unit of Daya Bay Nuclear Power Plant RPV, stud hole's lubricating machine are practically used. The practical using of RPV stud hole's lubricating machine proved that its all technical characteristics and functions have already met requirements of technical specification of the proprietor

  1. The performance of a prototype device designed to evaluate general quality parameters of X-ray equipment

    Science.gov (United States)

    Murata, C. H.; Fernandes, D. C.; Lavínia, N. C.; Caldas, L. V. E.; Pires, S. R.; Medeiros, R. B.

    2014-02-01

    The performance of radiological equipment can be assessed using non-invasive methods and portable instruments that can analyze an X-ray beam with just one exposure. These instruments use either an ionization chamber or a state solid detector (SSD) to evaluate X-ray beam parameters. In Brazil, no such instruments are currently being manufactured; consequently, these instruments come at a higher cost to users due to importation taxes. Additionally, quality control tests are time consuming and impose a high workload on the X-ray tubes when evaluating their performance parameters. The assessment of some parameters, such as the half-value layer (HVL), requires several exposures; however, this can be reduced by using a SSD that requires only a single exposure. One such SSD uses photodiodes designed for high X-ray sensitivity without the use of scintillation crystals. This sensitivity allows one electron-hole pair to be created per 3.63 eV of incident energy, resulting in extremely high and stable quantum efficiencies. These silicon photodiodes operate by absorbing photons and generating a flow of current that is proportional to the incident power. The aim of this study was to show the response of the solid sensor PIN RD100A detector in a multifunctional X-ray analysis system that is designed to evaluate the average peak voltage (kVp), exposure time, and HVL of radiological equipment. For this purpose, a prototype board that uses four SSDs was developed to measure kVp, exposure time, and HVL using a single exposure. The reproducibility and accuracy of the results were compared to that of different X-ray beam analysis instruments. The kVp reproducibility and accuracy results were 2% and 3%, respectively; the exposure time reproducibility and accuracy results were 2% and 1%, respectively; and the HVL accuracy was ±2%. The prototype's methodology was able to calculate these parameters with appropriate reproducibility and accuracy. Therefore, the prototype can be considered

  2. Design and Analysis of a Spurious Switching Suppression Technique Equipped Low Power Multiplier with Hybrid Encoding Scheme

    Directory of Open Access Journals (Sweden)

    M.Madheswaran

    2009-12-01

    Full Text Available Multiplication is an arithmetic operation that is mostly used in Digital Signal Processing (DSP and communication applications. Efficient implementation of the multipliers is required in many applications. The design and analysis of Spurious Switching Suppression Technique (SSST equipped low power multiplier with hybrid encoding is presented in this paper. The proposed encoding technique reduces the number of switching activity and dynamic power consumption by analyzing the bit patterns in the input data. In this proposed encoding scheme, the operation is executed depends upon the number of 1’s and its position in the multiplier data. The architecture of the proposed multiplier is designed using a low power full adder which consumes less power than the other adder architectures. The switching activity of the proposed multiplier has been reduced by 86% and 46% compared with conventional and Booth multiplier respectively. It is observed from the device level simulation using TANNER 12.6 EDA that the power consumption of the proposed multiplier has been reduced by 87% and 26% compared with conventional and Booth multiplier. Keywords-component; Low power VLSI Design, Booth Multiplier, Hybrid encoding.

  3. The influence of deposition parameters and gaseous detonation equipment design on the coating formation

    International Nuclear Information System (INIS)

    The paper devoted to the problems of development of the problem-oriented dialogue program complex for direct computational experiment in the chain detonation gun -gas-powder feeding-high-temperature high-velocity jet- coating. The formation of structure and properties of coatings are determining by large quantity of factors. At the first approaching the conditions of coatings formation are determined by shape, sizes, velocity and temperature of particles, their texture and aggregative state, spatio-temporal distribution of powder particles into impulse heterogeneous jet, microrelief, texture and temperature gradient of substrate surface layer, rate of fire, etc. More detailed consideration is demanding taking into account a number of other factors as used gas mixture, spatio- temporal characteristics of fresh charge into barrel, kinematics of spraying process, design philosophy of sprayed component, main material, etc. However, the starting point in this complicated process of coating obtaining is the formation of start elements of coating in the form of individual particles sprayed onto substrate. The systems of mathematical models and information interchange in the time of optimization of engineering procedures of detonation spraying of coatings are examined. The base of an expert system to assist detonation spray coating process is a dialogue modeling complex. It represent a stationary developed complex of methodical, algorithmic, software and information environment, which assure the essential promotion of effectiveness of development work, investigations and training. (author)

  4. Bioconjugation and stabilisation of biomolecules in biosensors.

    Science.gov (United States)

    Liébana, Susana; Drago, Guido A

    2016-06-30

    Suitable bioconjugation strategies and stabilisation of biomolecules on electrodes is essential for the development of novel and commercially viable biosensors. In the present review, the functional groups that comprise the selectable targets for practical bioconjugation methods are discussed. We focus on describing the most common immobilisation techniques used in biosensor construction, which are classified into irreversible and reversible methods. Concerning the stability of proteins, the two main types of stability may be defined as (i) storage or shelf stability, and (ii) operational stability. Both types of stability are explained, as well as the introduction of an electrophoretic technique for predicting protein-polymer interactions. In addition, solution and dry stabilisation as well as stabilisation using the covalent immobilisation of proteins are discussed including possible factors that influence stability. Finally, the integration of nanomaterials, such as magnetic particles, with protein immobilisation is discussed in relation to protein stability studies. PMID:27365036

  5. Equipment concept design and development plans for microgravity science and applications research on space station: Combustion tunnel, laser diagnostic system, advanced modular furnace, integrated electronics laboratory

    Science.gov (United States)

    Uhran, M. L.; Youngblood, W. W.; Georgekutty, T.; Fiske, M. R.; Wear, W. O.

    1986-01-01

    Taking advantage of the microgravity environment of space NASA has initiated the preliminary design of a permanently manned space station that will support technological advances in process science and stimulate the development of new and improved materials having applications across the commercial spectrum. Previous studies have been performed to define from the researcher's perspective, the requirements for laboratory equipment to accommodate microgravity experiments on the space station. Functional requirements for the identified experimental apparatus and support equipment were determined. From these hardware requirements, several items were selected for concept designs and subsequent formulation of development plans. This report documents the concept designs and development plans for two items of experiment apparatus - the Combustion Tunnel and the Advanced Modular Furnace, and two items of support equipment the Laser Diagnostic System and the Integrated Electronics Laboratory. For each concept design, key technology developments were identified that are required to enable or enhance the development of the respective hardware.

  6. The Design of Ground Test Equipment on Special Computer%某计算机地面检测设备的设计

    Institute of Scientific and Technical Information of China (English)

    田琨

    2001-01-01

    机载电子设备的研制和开发,需要功能完备的地面检测设备。本文简要介绍了某计算机基于微程序的地面检测设备的软硬件设计及其实施途径。%The research of equipment on airplane need ground test equipment which have maturity functions. This paper introduces design of hardware, software of the ground test equipment of the some airplane computer based micro-program, and the method how to carry into execution.

  7. Tapered Optical Fiber Sensor for Label-Free Detection of Biomolecules

    Science.gov (United States)

    Tian, Ye; Wang, Wenhui; Wu, Nan; Zou, Xiaotian; Wang, Xingwei

    2011-01-01

    This paper presents a fast, highly sensitive and low-cost tapered optical fiber biosensor that enables the label-free detection of biomolecules. The sensor takes advantage of the interference effect between the fiber’s first two propagation modes along the taper waist region. The biomolecules bonded on the taper surface were determined by demodulating the transmission spectrum phase shift. Because of the sharp spectrum fringe signals, as well as a relatively long biomolecule testing region, the sensor displayed a fast response and was highly sensitive. To better understand the influence of various biomolecules on the sensor, a numerical simulation that varied biolayer parameters such as thickness and refractive index was performed. The results showed that the spectrum fringe shift was obvious to be measured even when the biolayer was only nanometers thick. A microchannel chip was designed and fabricated for the protection of the sensor and biotesting. Microelectromechanical systems (MEMS) fabrication techniques were used to precisely control the profile and depth of the microchannel on the silicon chip with an accuracy of 2 μm. A tapered optical fiber biosensor was fabricated and evaluated with an Immune globulin G (IgG) antibody-antigen pair. PMID:22163821

  8. Tapered Optical Fiber Sensor for Label-Free Detection of Biomolecules

    Directory of Open Access Journals (Sweden)

    Xingwei Wang

    2011-03-01

    Full Text Available This paper presents a fast, highly sensitive and low-cost tapered optical fiber biosensor that enables the label-free detection of biomolecules. The sensor takes advantage of the interference effect between the fiber’s first two propagation modes along the taper waist region. The biomolecules bonded on the taper surface were determined by demodulating the transmission spectrum phase shift. Because of the sharp spectrum fringe signals, as well as a relatively long biomolecule testing region, the sensor displayed a fast response and was highly sensitive. To better understand the influence of various biomolecules on the sensor, a numerical simulation that varied biolayer parameters such as thickness and refractive index was performed. The results showed that the spectrum fringe shift was obvious to be measured even when the biolayer was only nanometers thick. A microchannel chip was designed and fabricated for the protection of the sensor and biotesting. Microelectromechanical systems (MEMS fabrication techniques were used to precisely control the profile and depth of the microchannel on the silicon chip with an accuracy of 2 μm. A tapered optical fiber biosensor was fabricated and evaluated with an Immune globulin G (IgG antibody-antigen pair.

  9. Assembly and actuation of nanomaterials using active biomolecules.

    Energy Technology Data Exchange (ETDEWEB)

    Spoerke, Erik David; Thayer, Gayle Echo; de Boer, Maarten Pieter; Bunker, Bruce Conrad; Liu, Jun; Corwin, Alex David; Gaudioso, Jennifer Marie; Sasaki, Darryl Yoshio; Boal, Andrew Kiskadden; Bachand, George David; Trent, Amanda M.; Bachand, Marlene; Rivera, Susan B.; Koch, Steven John

    2005-11-01

    The formation and functions of living materials and organisms are fundamentally different from those of synthetic materials and devices. Synthetic materials tend to have static structures, and are not capable of adapting to the functional needs of changing environments. In contrast, living systems utilize energy to create, heal, reconfigure, and dismantle materials in a dynamic, non-equilibrium fashion. The overall goal of the project was to organize and reconfigure functional assemblies of nanoparticles using strategies that mimic those found in living systems. Active assembly of nanostructures was studied using active biomolecules to drive the organization and assembly of nanocomposite materials. In this system, kinesin motor proteins and microtubules were used to direct the transport and interactions of nanoparticles at synthetic interfaces. In addition, the kinesin/microtubule transport system was used to actively assemble nanocomposite materials capable of storing significant elastic energy. Novel biophysical measurement tools were also developed for measuring the collective force generated by kinesin motor proteins, which will provide insight on the mechanical constraints of active assembly processes. Responsive reconfiguration of nanostructures was studied in terms of using active biomolecules to mediate the optical properties of quantum dot (QD) arrays through modulation of inter-particle spacing and associated energy transfer interaction. Design rules for kinesin-based transport of a wide range of nanoscale cargo (e.g., nanocrystal quantum dots, micron-sized polymer spheres) were developed. Three-dimensional microtubule organizing centers were assembled in which the polar orientation of the microtubules was controlled by a multi-staged assembly process. Overall, a number of enabling technologies were developed over the course of this project, and will drive the exploitation of energy-driven processes to regulate the assembly, disassembly, and dynamic

  10. Design of Hoisting Equipment for Transit Theodolite%经纬仪吊装机构设计

    Institute of Scientific and Technical Information of China (English)

    徐燕; 佘晶

    2012-01-01

    介绍了经纬仪吊装机构设计过程,包括吊装机构的方案选择、内外管的强度校核以及手拉葫芦及轴承的选型。试验证明,该吊装机构能满足经纬仪的出入舱要求,安全可靠,操作简单快捷。与随车吊相比,该吊装机构加工成本低。%The design method and the manufacturing process of hoisting equipment for the transit theodolite are introduced. The design plan selection, the strength check of the inside and outside tubes, the model selections of the chain block and the bearing are presented, respectively. Exper- imental results show that the lifting mechanism can meet the entrance and exit requirements for the transit theodolite. The system has advantages of safe and reliable, easy operation and conve- nient process. In addition, the cost is fewer than that of the truck mounted crane.

  11. Preparation of supramolecular hydrogel-enzyme hybrids exhibiting biomolecule-responsive gel degradation.

    Science.gov (United States)

    Shigemitsu, Hajime; Fujisaku, Takahiro; Onogi, Shoji; Yoshii, Tatsuyuki; Ikeda, Masato; Hamachi, Itaru

    2016-09-01

    Hydrogelators are small, self-assembling molecules that form supramolecular nanofiber networks that exhibit unique dynamic properties. Development of supramolecular hydrogels that degrade in response to various biomolecules could potentially be used for applications in areas such as drug delivery and diagnostics. Here we provide a synthetic procedure for preparing redox-responsive supramolecular hydrogelators that are used to create hydrogels that degrade in response to oxidizing or reducing conditions. The synthesis takes ∼2-4 d, and it can potentially be carried out in parallel to prepare multiple hydrogelator candidates. This described solid-phase peptide synthesis protocol can be used to produce previously described hydrogelators or to construct a focused molecular library to efficiently discover and optimize new hydrogelators. In addition, we describe the preparation of redox-responsive supramolecular hydrogel-enzyme hybrids that are created by mixing aqueous solutions of hydrogelators and enzymes, which requires 2 h for completion. The resultant supramolecular hydrogel-enzyme hybrids exhibit gel degradation in response to various biomolecules, and can be rationally designed by connecting the chemical reactions of the hydrogelators with enzymatic reactions. Gel degradation in response to biomolecules as triggers occurs within a few hours. We also describe the preparation of hydrogel-enzyme hybrids arrayed on flat glass slides, enabling high-throughput analysis of biomolecules such as glucose, uric acid, lactate and so on by gel degradation, which is detectable by the naked eye. The protocol requires ∼6 h to prepare the hydrogel-enzyme hybrid array and to complete the biomolecule assay. PMID:27560177

  12. Ionic strength independence of charge distributions in solvation of biomolecules.

    Science.gov (United States)

    Virtanen, J J; Sosnick, T R; Freed, K F

    2014-12-14

    Electrostatic forces enormously impact the structure, interactions, and function of biomolecules. We perform all-atom molecular dynamics simulations for 5 proteins and 5 RNAs to determine the dependence on ionic strength of the ion and water charge distributions surrounding the biomolecules, as well as the contributions of ions to the electrostatic free energy of interaction between the biomolecule and the surrounding salt solution (for a total of 40 different biomolecule/solvent combinations). Although water provides the dominant contribution to the charge density distribution and to the electrostatic potential even in 1M NaCl solutions, the contributions of water molecules and of ions to the total electrostatic interaction free energy with the solvated biomolecule are comparable. The electrostatic biomolecule/solvent interaction energies and the total charge distribution exhibit a remarkable insensitivity to salt concentrations over a huge range of salt concentrations (20 mM to 1M NaCl). The electrostatic potentials near the biomolecule's surface obtained from the MD simulations differ markedly, as expected, from the potentials predicted by continuum dielectric models, even though the total electrostatic interaction free energies are within 11% of each other. PMID:25494774

  13. GroPBS: Fast Solver for Implicit Electrostatics of Biomolecules

    Directory of Open Access Journals (Sweden)

    Franziska eBertelshofer

    2015-11-01

    Full Text Available Knowledge about the electrostatic potential on the surface of biomolecules or biomembranes under physiological conditions is an important step in the attempt to characterize the physico-chemical properties of these molecules and in particular also their interactions with each other. Additionally, knowledge about solution electrostatics may guide also the design of molecules with specified properties. However, explicit water models come at a high computational cost, rendering them unsuitable for large design studies or for docking purposes. Implicit models with the water phase treated as a continuum require the numerical solution of the Poisson-Boltzmann Equation (PBE. Here, we present a new flexible program for the numerical solution of the PBE, allowing for different geometries, and the explicit and implicit inclusion of membranes. It involves a discretization of space and the computation of the molecular surface. The PBE is solved using finite differences, the resulting set of equations is solved using a Gauss-Seidel method. It is shown for the example of the sucrose transporter ScrY that the implicit inclusion of a surrounding membrane has a strong effect also on the electrostatics within the pore region and thus need to be carefully considered e.g. in design studies on membrane proteins.

  14. Biomolecule-mediated synthesis of nanocrystalline semiconductors

    Science.gov (United States)

    Bae, Weon

    CdS and ZnS nanocrystalline semiconductors (NCs) were prepared by titrating inorganic sulfide into preformed Cd(II)- or Zn(II)-complexes of phytochelatins, glutathione or cysteine. This strategy resulted in the formation NCs capped by the chosen biomolecule. The range of sizes and their distributions depended primarily on the quantity of sulfide titrated and the biomolecule chosen for the initial metallo-complex. The processes of NC formation were studied by absorption and fluorescence spectrophotometry. The size distribution was analyzed by gel permeation chromatography. Ethanol precipitation of NCs under aqueous conditions was used to isolate nanoparticles within a very narrow size-range. Reduction of selected dyes was also studied on the surfaces of NCs. Glutathione-capped CdS nanoparticles exhibited significant size heterogeneity even at a single sulfide titration. In contrast, phytochelatins showed much less dispersion in size at a given sulfide titration. Phytochelatins could replace glutathione without changing the size of glutathione-capped CdS nanoparticles. Cysteine appeared to be intermediate between glutathione and phytochelatins in the formation of CdS nanoparticles. The calculated radii, using an effective mass approximation method, were 10.8-17.3, 10.6-11.8, and 13.5-15.5A for glutathione-, phytochelatin-, and cysteine-capped CdS nanoparticles, respectively. Cysteine-capped ZnS showed narrower size distribution than glutathione-capped ZnS. However, elevated temperatures were necessary to accomplish optimal yields of cysteine-capped ZnS NCs. An additional control over the size distribution of NCs was achieved by size-selective precipitation with ethanol. These procedures led to the isolation of nanoparticles that were more uniform in size and chemical compositions as determined by spectroscopic and chemical analyses of size-fractionated samples. Precipitation also allowed preparation of large quantities of powdered nanoparticles that could be

  15. Noncovalent Labeling of Biomolecules with Red and Near- Infrared Dyes

    Directory of Open Access Journals (Sweden)

    Lucjan Strekowski

    2004-02-01

    Full Text Available Biopolymers such as proteins and nucleic acids can be labeled with a fluorescent marker to allow for their detection. Covalent labeling is achieved by the reaction of an appropriately functionalized dye marker with a reactive group on a biomolecule. The recent trend, however, is the use of noncovalent labeling that results from strong hydrophobic and/or ionic interactions between the marker and biomolecule of interest. The main advantage of noncovalent labeling is that it affects the functional activity of the biomolecule to a lesser extent. The applications of luminescent cyanine and squarylium dyes are reviewed.

  16. Microfluidic Radiometal Labeling Systems for Biomolecules

    Energy Technology Data Exchange (ETDEWEB)

    Reichert, D E; Kenis, P J. A.

    2011-12-29

    In a typical labeling procedure with radiometals, such as Cu-64 and Ga-68; a very large (~ 100-fold) excess of the non-radioactive reactant (precursor) is used to promote rapid and efficient incorporation of the radioisotope into the PET imaging agent. In order to achieve high specific activities, careful control of reaction conditions and extensive chromatographic purifications are required in order to separate the labeled compounds from the cold precursors. Here we propose a microfluidic approach to overcome these problems, and achieve high specific activities in a more convenient, semi-automated fashion and faster time frame. Microfluidic reactors, consisting of a network of micron-sized channels (typical dimensions in the range 10 - 300¼m), filters, separation columns, electrodes and reaction loops/chambers etched onto a solid substrate, are now emerging as an extremely useful technology for the intensification and miniaturization of chemical processes. The ability to manipulate, process and analyze reagent concentrations and reaction interfaces in both space and time within the channel network of a microreactor provides the fine level of reaction control that is desirable in PET radiochemistry practice. These factors can bring radiometal labeling, specifically the preparation of radio-labeled biomolecules such as antibodies, much closer to their theoretical maximum specific activities.

  17. Formation of biomolecule precursors in space

    Energy Technology Data Exchange (ETDEWEB)

    Geppert, W D [Department of Physics, Stockholm University, Alba Nova, Roslagstullbacken 21, SE-10691, Stockholm (Sweden); Vigren, E [Department of Physics, Stockholm University, Alba Nova, Roslagstullbacken 21, SE-10691, Stockholm (Sweden); Hamberg, M [Department of Physics, Stockholm University, Alba Nova, Roslagstullbacken 21, SE-10691, Stockholm (Sweden); Zhaunerchyk, V [Department of Physics, Stockholm University, Alba Nova, Roslagstullbacken 21, SE-10691, Stockholm (Sweden); Thomas, R D [Department of Physics, Stockholm University, Alba Nova, Roslagstullbacken 21, SE-10691, Stockholm (Sweden); Kaminska, M [Institute of Physics, Swieetokrzyska Academy, ul. Swieokrzyska 15, PL-25406, Kielce (Poland); Millar, T J [Astrophysics Research Centre, Queen' s University Belfast, BT7 1NN, Belfast, Northern Ireland (United Kingdom); Semaniak, J [Institute of Physics, Swieetokrzyska Academy, ul. Swieokrzyska 15, PL-25406, Kielce (Poland); Roberts, H [Astrophysics Research Centre, Queen' s University Belfast, BT7 1NN, Belfast, Northern Ireland (United Kingdom); Hellberg, F [Department of Physics, Stockholm University, Alba Nova, Roslagstullbacken 21, SE-10691, Stockholm (Sweden); Oesterdahl, F [Department of Physics, Royal Institute of Technology, Alba Nova, Roslagstullbacken 21, SE-10691, Stockholm (Sweden); Ehlerding, A [Department of Physics, Stockholm University, Alba Nova, Roslagstullbacken 21, SE-10691, Stockholm (Sweden); Larsson, M [Department of Physics, Stockholm University, Alba Nova, Roslagstullbacken 21, SE-10691, Stockholm (Sweden)

    2007-11-15

    Alcohols and nitriles not only play an important role as templates for synthesis of larger molecules in the interstellar medium and planetary atmospheres, but they can also be regarded as precursors for biomolecules. Alcohols can form carbohydrates through reaction with HCO and nitriles can be hydrolysed to amino acids in aqueous solutions, which is the final step of the well-known Strecker synthesis. Therefore the question of the pathways of formation of alcohols and nitriles and the efficiency and the product distribution of their subsequent degradation reactions in the above-mentioned astrophysical environments is of great interest. In both processes dissociative recombination reactions of protonated nitriles and alcohols may play a major role and are included in models of interstellar clouds and planetary atmospheres. However, the reaction rate coefficients and product branching ratios for the majority of these processes are so far still unknown, which adversely affects the quality of predictions of model calculations. In this Contribution, we therefore present branching ratios and rate constants of the dissociative recombination of protonated methanol (CH{sub 3}OH{sub 2}), as well as protonated acetonitrile (CH{sub 3}CNH{sup +}), acrylonitrile (C{sub 2}H{sub 3}CNH{sup +}) and cyanoacetylene (HC{sup 3}NH{sup +}). The impact of the obtained new data on model calculations of abundances of important interstellar molecules in dark clouds is discussed.

  18. 新型口香糖清除器的设计%Design of New Chewing Gum Removal Equipment

    Institute of Scientific and Technical Information of China (English)

    鲁杰; 艾书义

    2012-01-01

    口香糖残留物粘着力强,易吸附灰尘和细菌,被丢弃后经日晒、踩踏,残留物与路面粘结,难以清除,严重影响城市的美观与卫生.因此口香糖残渣清理已成为环卫工作面临的重大难题.本文分析了国内口香糖残留清除方法及清除机械的现状,本着高效节能的理念,设计出一种新型半自动口香糖清除器.%Strong adhesion of chewing gum residues, easy to absorb the on the city's appearance and health, in particular, after the sun and trampl dust and bacteria, serious impact e, chewing gum residues are even more difficult to remove. Therefore, chewing gum residue removal has become a major problem facing public places. This paper analyses the domestic chewing gum residue removal methods and the current situation of removal machines, and designs a new type of chewing gum residue removal equipment.

  19. Design, Fabrication and pseudo Field Evaluation of a Sugar Beet Crust Breaker and Weeding Unit Equipped with an Infrared Sensor

    Directory of Open Access Journals (Sweden)

    E Chaligar

    2014-09-01

    Full Text Available In conventional cultivation of sugar beet the weeding and crust breaking are mostly performed manually. The objectives of this research were to design, fabricate and evaluate a soil crust breaker and weeding implement equipped with a detecting sensor. Each unit consisted of a distance detecting sensor and a hydro-motor for driving the blades and pneumatic valves for moving the blades. The hydro-motor was activated by the sensors. To avoid damaging the plants, a command signal was sent to the pneumatic valves to move the blades up and down and pass safely. Three configurations of cutting blades were considered which could be mounted to the crust breaker. The field evaluation was conducted with two tractor forward speeds (0.4 and 1 km h-1 and four plant-to-plant spacings within rows (20, 25, 30 and 40 cm all with three different blade shapes. For field evaluation split plot experiments arranged in a completely randomized block design with three replications. The number of plants damaged (evaluated only for four-lobe blades and size of broken crusts (evaluated for all blade shapes for various treatments were recorded and compared. The results of analysis indicated that the higher the inter-row spacing the lower the injury to the plant. The highest and the least damage to the plants occurred for within-row plant spacings of 20 and 40 cm, respectively. The forward speed was also significantly affected the percent of plant damaged. The forward speed of 1 km h-1 at 20 cm spacing had the most (59% and the speed of 0.40 km h-1 at 40 cm spacing had the least effect (3.3% on the percent of plant damage. The two-lobe blade could result in the maximum surface area broken.

  20. 基于Django框架的设备管理系统的设计与实现%Django Framework Based Equipment Management System Design and Implementation

    Institute of Scientific and Technical Information of China (English)

    阳祝

    2013-01-01

    该文通过分析当前设备管理系统的应用场景和使用情况,将设备管理系统分解为若干模块,以用户角色为基础设计了一套完整的电子化设备管理系统。利用Python语言设计与开发了基于Django框架的设备管理系统。%This paper analyzes the current device management system applications and usage scenarios, the equipment manage-ment system is decomposed into several modules, user-role-based design of a complete set of electronic equipment management system. Design and development using the Python language Django framework based equipment management system.

  1. 典型喷淋悬挂式前处理设备设计%The Design of Typical Spray Suspension Treatment Equipment

    Institute of Scientific and Technical Information of China (English)

    邓金龙

    2013-01-01

    The design of typical spray suspension pretreatment equipment was mainly introduced, pretreatment of a particular product washing machine spray was used as example, the pretreatment equipment segment size, calculation of tank body size, the layout of spray pipe and main equipment design principles were discussed.%  主要介绍典型喷淋悬挂式前处理设备的设计,以某产品洗衣机喷淋前处理为例,对前处理设备各段尺寸、槽体尺寸计算、喷淋管道布置以及主要设备设计原则等进行论述。

  2. Design of Hydraulic Protection Equipment Served the Disabled Weight-lifting%残疾人举重液压伺服保护装置设计

    Institute of Scientific and Technical Information of China (English)

    汪功明

    2015-01-01

    A kind of hydraulic protection equipment served the disabled weight⁃lifting was designed. The equipment consisted of guide rail, hydraulic following unit and hydraulic lifting unit. It mainly depended on hydraulic servo theory to work. The technical pro⁃posal and the model designs of the core structure of the equipment were stated.%设计一种残疾人举重保护装置,该装置由导轨、液压跟随单元、液压托举单元等三部分组成,主要依据液压伺服原理工作。阐述了该装置的技术方案,并对装置的核心结构做了选型设计。

  3. Engineered Carbon-Nanomaterial-Based Electrochemical Sensors for Biomolecules.

    Science.gov (United States)

    Tiwari, Jitendra N; Vij, Varun; Kemp, K Christian; Kim, Kwang S

    2016-01-26

    The study of electrochemical behavior of bioactive molecules has become one of the most rapidly developing scientific fields. Biotechnology and biomedical engineering fields have a vested interest in constructing more precise and accurate voltammetric/amperometric biosensors. One rapidly growing area of biosensor design involves incorporation of carbon-based nanomaterials in working electrodes, such as one-dimensional carbon nanotubes, two-dimensional graphene, and graphene oxide. In this review article, we give a brief overview describing the voltammetric techniques and how these techniques are applied in biosensing, as well as the details surrounding important biosensing concepts of sensitivity and limits of detection. Building on these important concepts, we show how the sensitivity and limit of detection can be tuned by including carbon-based nanomaterials in the fabrication of biosensors. The sensing of biomolecules including glucose, dopamine, proteins, enzymes, uric acid, DNA, RNA, and H2O2 traditionally employs enzymes in detection; however, these enzymes denature easily, and as such, enzymeless methods are highly desired. Here we draw an important distinction between enzymeless and enzyme-containing carbon-nanomaterial-based biosensors. The review ends with an outlook of future concepts that can be employed in biosensor fabrication, as well as limitations of already proposed materials and how such sensing can be enhanced. As such, this review can act as a roadmap to guide researchers toward concepts that can be employed in the design of next generation biosensors, while also highlighting the current advancements in the field.

  4. Engineered Carbon-Nanomaterial-Based Electrochemical Sensors for Biomolecules.

    Science.gov (United States)

    Tiwari, Jitendra N; Vij, Varun; Kemp, K Christian; Kim, Kwang S

    2016-01-26

    The study of electrochemical behavior of bioactive molecules has become one of the most rapidly developing scientific fields. Biotechnology and biomedical engineering fields have a vested interest in constructing more precise and accurate voltammetric/amperometric biosensors. One rapidly growing area of biosensor design involves incorporation of carbon-based nanomaterials in working electrodes, such as one-dimensional carbon nanotubes, two-dimensional graphene, and graphene oxide. In this review article, we give a brief overview describing the voltammetric techniques and how these techniques are applied in biosensing, as well as the details surrounding important biosensing concepts of sensitivity and limits of detection. Building on these important concepts, we show how the sensitivity and limit of detection can be tuned by including carbon-based nanomaterials in the fabrication of biosensors. The sensing of biomolecules including glucose, dopamine, proteins, enzymes, uric acid, DNA, RNA, and H2O2 traditionally employs enzymes in detection; however, these enzymes denature easily, and as such, enzymeless methods are highly desired. Here we draw an important distinction between enzymeless and enzyme-containing carbon-nanomaterial-based biosensors. The review ends with an outlook of future concepts that can be employed in biosensor fabrication, as well as limitations of already proposed materials and how such sensing can be enhanced. As such, this review can act as a roadmap to guide researchers toward concepts that can be employed in the design of next generation biosensors, while also highlighting the current advancements in the field. PMID:26579616

  5. On the mobility of biomolecules : a fluorescence microscopy approach

    NARCIS (Netherlands)

    Bogaart, Geert van den

    2008-01-01

    This thesis describes the development and application of a number of fluorescence spectroscopy related techniques (FCS, FRAP, DCFBA) to measure diffusion of biomolecules in cells, in membranes and through membrane pores.

  6. Cellular content of biomolecules in sub-seafloor microbial communities

    DEFF Research Database (Denmark)

    Braun, Stefan; Morono, Yuki; Becker, Kevin W.;

    2016-01-01

    purified cell extracts had an average content of amino acids and lipids of 23–28 fg cell-1 and 2.3 fg cell-1, respectively, with an estimated carbon content of 19–24 fg cell-1. In the sediment, the amount of biomolecules associated with vegetative cells was up to 70-fold lower than the total biomolecule......Microbial biomolecules, typically from the cell envelope, can provide crucial information about distribution, activity, and adaptations of sub-seafloor microbial communities. However, when cells die these molecules can be preserved in the sediment on timescales that are likely longer than...... the lifetime of their microbial sources. Here we provide for the first time measurements of the cellular content of biomolecules in sedimentary microbial cells. We separated intact cells from sediment matrices in samples from surficial, deeply buried, organic-rich, and organic-lean marine sediments by density...

  7. Design and fabrication of equipment and devices for a Radiotherapy department; Diseno y fabricacion de equipos y aditamentos para un departamento de Radioterapia

    Energy Technology Data Exchange (ETDEWEB)

    Picon, C.L.; Zaharia B, M. [Departamento de Radioterapia. Instituto de Enfermedades Neoplasicas, Av. Angamos Este 2520, Lima (Peru)

    1998-12-31

    The objective of this work is to present the possibility to design and construct utilizing local technology, a series of equipment and devices necessaries for a routine in a Radiotherapy Department with typical budget in the Latin-American hospitals. (Author)

  8. Cellular content of biomolecules in sub-seafloor microbial communities

    Science.gov (United States)

    Braun, Stefan; Morono, Yuki; Becker, Kevin W.; Hinrichs, Kai-Uwe; Kjeldsen, Kasper U.; Jørgensen, Bo B.; Lomstein, Bente Aa.

    2016-09-01

    Microbial biomolecules, typically from the cell envelope, can provide crucial information about distribution, activity, and adaptations of sub-seafloor microbial communities. However, when cells die these molecules can be preserved in the sediment on timescales that are likely longer than the lifetime of their microbial sources. Here we provide for the first time measurements of the cellular content of biomolecules in sedimentary microbial cells. We separated intact cells from sediment matrices in samples from surficial, deeply buried, organic-rich, and organic-lean marine sediments by density centrifugation. Amino acids, amino sugars, muramic acid, and intact polar lipids were analyzed in both whole sediment and cell extract, and cell separation was optimized and evaluated in terms of purity, separation efficiency, taxonomic resemblance, and compatibility to high-performance liquid chromatography and mass spectrometry for biomolecule analyses. Because cell extracts from density centrifugation still contained considerable amounts of detrital particles and non-cellular biomolecules, we further purified cells from two samples by fluorescence-activated cell sorting (FACS). Cells from these highly purified cell extracts had an average content of amino acids and lipids of 23-28 fg cell-1 and 2.3 fg cell-1, respectively, with an estimated carbon content of 19-24 fg cell-1. In the sediment, the amount of biomolecules associated with vegetative cells was up to 70-fold lower than the total biomolecule content. We find that the cellular content of biomolecules in the marine subsurface is up to four times lower than previous estimates. Our approach will facilitate and improve the use of biomolecules as proxies for microbial abundance in environmental samples and ultimately provide better global estimates of microbial biomass.

  9. An integrated platform for biomolecule interaction analysis

    Science.gov (United States)

    Jan, Chia-Ming; Tsai, Pei-I.; Chou, Shin-Ting; Lee, Shu-Sheng; Lee, Chih-Kung

    2013-02-01

    We developed a new metrology platform which can detect real-time changes in both a phase-interrogation mode and intensity mode of a SPR (surface plasmon resonance). We integrated a SPR and ellipsometer to a biosensor chip platform to create a new biomolecular interaction measurement mechanism. We adopted a conductive ITO (indium-tinoxide) film to the bio-sensor platform chip to expand the dynamic range and improve measurement accuracy. The thickness of the conductive film and the suitable voltage constants were found to enhance performance. A circularly polarized ellipsometry configuration was incorporated into the newly developed platform to measure the label-free interactions of recombinant human C-reactive protein (CRP) with immobilized biomolecule target monoclonal human CRP antibody at various concentrations. CRP was chosen as it is a cardiovascular risk biomarker and is an acute phase reactant as well as a specific prognostic indicator for inflammation. We found that the sensitivity of a phaseinterrogation SPR is predominantly dependent on the optimization of the sample incidence angle. The effect of the ITO layer effective index under DC and AC effects as well as an optimal modulation were experimentally performed and discussed. Our experimental results showed that the modulated dynamic range for phase detection was 10E-2 RIU based on a current effect and 10E-4 RIU based on a potential effect of which a 0.55 (°/RIU) measurement was found by angular-interrogation. The performance of our newly developed metrology platform was characterized to have a higher sensitivity and less dynamic range when compared to a traditional full-field measurement system.

  10. Multi-state modeling of biomolecules.

    Directory of Open Access Journals (Sweden)

    Melanie I Stefan

    2014-09-01

    Full Text Available Multi-state modeling of biomolecules refers to a series of techniques used to represent and compute the behavior of biological molecules or complexes that can adopt a large number of possible functional states. Biological signaling systems often rely on complexes of biological macromolecules that can undergo several functionally significant modifications that are mutually compatible. Thus, they can exist in a very large number of functionally different states. Modeling such multi-state systems poses two problems: the problem of how to describe and specify a multi-state system (the "specification problem" and the problem of how to use a computer to simulate the progress of the system over time (the "computation problem". To address the specification problem, modelers have in recent years moved away from explicit specification of all possible states and towards rule-based formalisms that allow for implicit model specification, including the κ-calculus, BioNetGen, the Allosteric Network Compiler, and others. To tackle the computation problem, they have turned to particle-based methods that have in many cases proved more computationally efficient than population-based methods based on ordinary differential equations, partial differential equations, or the Gillespie stochastic simulation algorithm. Given current computing technology, particle-based methods are sometimes the only possible option. Particle-based simulators fall into two further categories: nonspatial simulators, such as StochSim, DYNSTOC, RuleMonkey, and the Network-Free Stochastic Simulator (NFSim, and spatial simulators, including Meredys, SRSim, and MCell. Modelers can thus choose from a variety of tools, the best choice depending on the particular problem. Development of faster and more powerful methods is ongoing, promising the ability to simulate ever more complex signaling processes in the future.

  11. Calculation and visualization of atomistic mechanical stresses in nanomaterials and biomolecules.

    Directory of Open Access Journals (Sweden)

    Andrew T Fenley

    Full Text Available Many biomolecules have machine-like functions, and accordingly are discussed in terms of mechanical properties like force and motion. However, the concept of stress, a mechanical property that is of fundamental importance in the study of macroscopic mechanics, is not commonly applied in the biomolecular context. We anticipate that microscopical stress analyses of biomolecules and nanomaterials will provide useful mechanistic insights and help guide molecular design. To enable such applications, we have developed Calculator of Atomistic Mechanical Stress (CAMS, an open-source software package for computing atomic resolution stresses from molecular dynamics (MD simulations. The software also enables decomposition of stress into contributions from bonded, nonbonded and Generalized Born potential terms. CAMS reads GROMACS topology and trajectory files, which are easily generated from AMBER files as well; and time-varying stresses may be animated and visualized in the VMD viewer. Here, we review relevant theory and present illustrative applications.

  12. Recent trends in carbon nanomaterial-based electrochemical sensors for biomolecules: A review

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Cheng; Denno, Madelaine E.; Pyakurel, Poojan; Venton, B. Jill, E-mail: jventon@virginia.edu

    2015-08-05

    Carbon nanomaterials are advantageous for electrochemical sensors because they increase the electroactive surface area, enhance electron transfer, and promote adsorption of molecules. Carbon nanotubes (CNTs) have been incorporated into electrochemical sensors for biomolecules and strategies have included the traditional dip coating and drop casting methods, direct growth of CNTs on electrodes and the use of CNT fibers and yarns made exclusively of CNTs. Recent research has also focused on utilizing many new types of carbon nanomaterials beyond CNTs. Forms of graphene are now increasingly popular for sensors including reduced graphene oxide, carbon nanohorns, graphene nanofoams, graphene nanorods, and graphene nanoflowers. In this review, we compare different carbon nanomaterial strategies for creating electrochemical sensors for biomolecules. Analytes covered include neurotransmitters and neurochemicals, such as dopamine, ascorbic acid, and serotonin; hydrogen peroxide; proteins, such as biomarkers; and DNA. The review also addresses enzyme-based electrodes that are used to detect non-electroactive species such as glucose, alcohols, and proteins. Finally, we analyze some of the future directions for the field, pointing out gaps in fundamental understanding of electron transfer to carbon nanomaterials and the need for more practical implementation of sensors. - Highlights: • We review the types of carbon nanomaterials used in electrochemical sensors. • Different materials and sensor designs are compared for classes of biomolecules. • Future challenges of better sensor design and implementation are assessed.

  13. Research, Calculation for Designing the Technological Equipment Line of Cementation with 3,000 Tonnes of Solid Waste/Year Capacity for ZOC Plan

    International Nuclear Information System (INIS)

    Technological process and equipment line for cementation with 3,000 tons of solid wastes/year capacity for ZOC plant was studied according to the quantity, the composition and the property of solid wastes from ZOC plant. The influence of several parameters with cementation process such as cement mixing ratio, size, moisture and NaCl content in residue, which affected to mechanical and chemical strength of waste block after cementation was evaluated. The calculation and designing for cementation equipment line were thus conducted and total investment cost of construction and installation as well as operation of this equipment line was also estimated. Radiation safety and environmental protection for waste treatment facility was calculated and the design on radiation safety and environmental protection for equipment line was proposed. Technological process and design document of this production line seemed to be reasonable because it is consistent with properties of wastes as well as it has been commonly used in the world to stabilize solid residues in nuclear industry. The advantages of this propose were simple structure of the devices, locally made, easy operation, locally available and inexpensive materials resulting in low cost of investment and operation. (author)

  14. Diagnostic and therapeutic perspectives in nuclear medicine: radiolabelled biomolecules

    International Nuclear Information System (INIS)

    From their beginning, the radiopharmaceuticals chemistry has gone to the study of the molecular chemistry. The radiopharmaceuticals are only in their capacity to detect such specific biochemical places as the receivers and the enzymes. With the recent obtaining of the complete structural sequence of the genome, it doesn't fit doubt of the importance that they have acquired the molecular images for the study from the genetic information to the alterations phenotypic in the chemistry of the human body. So, the future of the diagnostic and therapeutic nuclear medicine, practically is based in the study of protein fragments, peptide structures and chains of DNA radiolabelled for the study of the metabolism In vivo. These investigations represent a substantial change in those paradigms of the pharmaceutical development, when using the own organic capacities as source of medications, instead of considering to the organism like a simple assay tube where molecules act, like they are most of the traditional medications. The investigation of new techniques to design complex stable of Tc-99m, Re-188, Lu-177, Y-90 and Dy-166/Ho-l66 with biomolecules that don't alter the specificity and in general the molecular properties of the same ones. it is a topic of world interest in the environment of the radiopharmaceutical chemistry. In this work some achievements and perspectives are presented on those main diagnostic and therapeutic radiopharmaceuticals of third generation. (Author)

  15. Cooling of electronic equipment

    DEFF Research Database (Denmark)

    A. Kristensen, Anders Schmidt

    2003-01-01

    Cooling of electronic equipment is studied. The design size of electronic equipment decrease causing the thermal density to increase. This affect the cooling which can cause for example failures of critical components due to overheating or thermal induced stresses. Initially a pin fin heat sink...

  16. Field Demonstration of Active Desiccant Modules Designed to Integrate with Standard Unitary Rooftop Package Equipment - Final Report: Phase 3

    Energy Technology Data Exchange (ETDEWEB)

    Fischer, J

    2004-03-15

    This report summarizes the investigation of two active desiccant module (ADM) pilot site installations initiated in 2001. Both pilot installations were retrofits at existing facilities served by conventional heating, ventilating, and air-conditioning (HVAC) systems that had encountered frequent humidity control, indoor air quality (IAQ), and other operational problems. Each installation involved combining a SEMCO, Inc., ADM (as described in Fischer and Sand 2002) with a standard packaged rooftop unit built by the Trane Company. A direct digital control (DDC) system integral to the ADM performed the dual function of controlling the ADM/rooftop combination and facilitating data collection, trending, and remote performance monitoring. The first installation involved providing preconditioned outdoor air to replace air exhausted from the large kitchen hood and bathrooms of a Hooters restaurant located in Rome, Georgia. This facility had previously added an additional rooftop unit in an attempt to achieve occupant comfort without success. The second involved conditioning the outdoor air delivered to each room of a wing of the Mountain Creek Inn at the Callaway Gardens resort. This hotel, designed in the ''motor lodge'' format with each room opening to the outdoors, is located in southwest Georgia. Controlling the space humidity always presented a serious challenge. Uncomfortable conditions and musty odors had caused many guests to request to move to other areas within the resort. This is the first field demonstration performed by Oak Ridge National Laboratory where significant energy savings, operating cost savings, and dramatically improved indoor environmental conditions can all be claimed as the results of a retrofit desiccant equipment field installation. The ADM/rooftop combination installed at the restaurant resulted in a reduction of about 34% in the electricity used by the building's air-conditioning system. This represents a reduction of

  17. 舰船电子设备可靠性理论研究%The theoretical research of reliability design for electronic equipment for ships

    Institute of Scientific and Technical Information of China (English)

    李伟; 李燕

    2014-01-01

    This is the theoretical research of reliability design for electronic equipment for ships. In this paper, through the study of the theory of reliability analysis of ship electronic equipment, study the characteristics of reliability parameters, formulate the reliability allocation and expected scheme and improve ship the inherent reliability of electronic equipment in the development and production stage, so as to reduce ship electronic equipment failure rate, reduce the maintenance support resources, reduce the maintenance cost and prolong the service life of the equipment.%本文是对舰船电子设备可靠性设计的理论研究。本文通过对舰船电子设备进行可靠性理论分析,研究其可靠性参数特点,制定可靠性分配与预计方案,提高舰船电子设备在研制生产阶段的固有可靠性,从而达到降低舰船电子设备故障率、减少维修保障资源、降低维修费用和延长设备使用寿命的目的。

  18. Design and Realization of Integrated Management System for Data Interoperability between Point-of-Care Testing Equipment and Hospital Information System

    Science.gov (United States)

    Park, Ki Sang; Heo, Hyuk

    2013-01-01

    Objectives The purpose of this study was to design an integrated data management system based on the POCT1-A2, LIS2-A, LIS2-A2, and HL7 standard to ensure data interoperability between mobile equipment, such as point-of-care testing equipment and the existing hospital data system, its efficiency was also evaluated. Methods The method of this study was intended to design and realize a data management system which would provide a solution for the problems that occur when point-of-care testing equipment is introduced to existing hospital data, after classifying such problems into connectivity, integration, and interoperability. This study also checked if the data management system plays a sufficient role as a bridge between the point-of-care testing equipment and the hospital information system through connection persistence and reliability testing, as well as data integration and interoperability testing. Results In comparison with the existing system, the data management system facilitated integration by improving the result receiving time, improving the collection rate, and by enabling the integration of disparate types of data into a single system. And it was found out that we can solve the problems related to connectivity, integration and interoperability through generating the message in standardized types. Conclusions It is expected that the proposed data management system, which is designed to improve the integration point-of-care testing equipment with existing systems, will establish a solid foundation on which better medical service may be provided by hospitals by improving the quality of patient service. PMID:24175121

  19. 地铁车辆段工艺设备辅助设计软件开发%Development of Computer-aided Design Software for Metro Depot Process Equipment Design

    Institute of Scientific and Technical Information of China (English)

    阿占文

    2016-01-01

    为实现地铁车辆段工艺设备标准化设计,提高设计质量和效率,通过研究工艺设备配置要求和设计要素,在MySQL数据库系统中建立地铁车辆段工艺设备数据库,利用Visual C#开发交互界面。软件内置地铁车辆段关键设备的三维模型,并按车辆段类型设定车间和设备配置模板,创建车辆段设计项目时可自动完成车间和工艺设备的配置,具有项目管理、三维模型导出、动画演示以及设备信息的查看与编辑等功能。该软件可应用于地铁车辆段工艺设备设计项目。%To achieve standardized design of metro depot process equipment, improve design quality and efficiency, process equipment database is built with MySQL and a graphical user interface is developed with Visual C # based on the study of process equipment configuration requirements. A 3D model of key depot equipment is established in the software to fulfill depot design with the template set in the software and to configure automatically workshop and process equipment. The software has the following features:project management, three-dimensional model exporting, animation viewing, viewing and editing of equipment information. The software can be used in the design of metro depot process equipment.

  20. 医院设备信息化管理及系统架构设计%Research on hospital equipment information management and system architecture design

    Institute of Scientific and Technical Information of China (English)

    王一栋; 陈刚; 牛伟新

    2016-01-01

    目的:探讨医院医疗设备管理方法,提出设备信息化管理需完成的任务及发展方向。突破常规的设计思路,进一步扩展医院设备信息化管理的范畴,真正实现信息化辅助下的医疗设备“全生命周期”管理目标。方法:全面分析医院日常医疗设备管理工作,设计出一种全新的“双核”设备信息系统架构,即采购前+采购后双核心架构。结果:基于该全新架构,可方便地实现系统模块化和全流程化设计。各种功能模块在“双核”架构下可灵活扩展,最终实现对医院医疗设备管理的全覆盖。结论:采购前+采购后的“双核”架构是一种稳定性强,且适宜扩展的系统架构,真实地还原了设备管理的本质,强调了“集体劳动”的作用,最终实现医疗设备动态、全生命周期管理的目标。%Objective:To clarify the essence of hospital equipment management and propose the task and development trend of information management need to be accomplished, and solve the bottleneck problem of system design, which is always focused on the process of hospital equipment information management promotion in our country.Methods: Comprehensively analyzed daily work of hospital equipment management, and designed a new "dual core" equipment information system architecture, which was "ex purchasing + post purchasing" dual core architecture.Results: Based on the new architecture, the hospital equipment information system can cover the entire equipment management workflow, and it made information transmission between jobs more efficiently, cooperation more closely, responsibilities more clearly, constraint more effectively.Conclusion:The new system architecture emphasizes the role of "collective labor". It depends on all the members of the equipment department to work together for the goal of achieving dynamic and full life-cycle equipment management.

  1. 健身器材控制界面的通用化设计%Generalized design of fitness equipment control interface

    Institute of Scientific and Technical Information of China (English)

    林能涛; 苏智剑; 乔帅; 闫扬义; 闫勇杰

    2014-01-01

    BACKGROUND:Health has been paid more and more attention in modern society, the health of those special groups, such as the elderly and the disabled, should also be brought to the forefront. As fitness equipment is more and more popular in contemporary, our focus should be transferred to the use of fitness equipment for these special groups. OBJECTIVE:To put forward the design strategy of fitness equipment control interface, for the special groups to use common fitness equipment comfortably and conveniently. METHODS:Based on the research of existing fitness equipment control interface, according to the usage habits and cognitive awareness of special groups on control interface, a new design strategy has been put forward using the general design method and ergonomics. RESULTS AND CONCLUSION:Based on the existing 45 kinds of exercise bikes, 84 kinds of running machines and 129 kinds of treadmil fitness equipments, we found that these equipments are designed for common users in the aspects of design and production process and control interface. Universal design is a design concept beyond the lack of capacity to meet the different needs of different populations, and designed products can reduce or even eliminate the difference in the ability of special populations and the general population in use. The new strategy makes design of fitness equipment control interface generalized and good man-machine interactive, which can meet the demand of the special groups and help them do fitness exercise to improve their health and body function.%背景:随着健身器材越来越普及的当代国情,关注的焦点也应该转移到老年人、残疾人等这些特殊群体对健身器材的使用上。  目的:提出健身器材控制界面通用化设计策略,以便于特殊人群能够舒适方便的使用普通健身器材。  方法:通过对现有健身器材控制界面的调查研究,结合特殊人群对控制界面的使用习惯和认知意识,

  2. Generalized design of fitness equipment control interface%健身器材控制界面的通用化设计

    Institute of Scientific and Technical Information of China (English)

    林能涛; 苏智剑; 乔帅; 闫扬义; 闫勇杰

    2014-01-01

    BACKGROUND:Health has been paid more and more attention in modern society, the health of those special groups, such as the elderly and the disabled, should also be brought to the forefront. As fitness equipment is more and more popular in contemporary, our focus should be transferred to the use of fitness equipment for these special groups. OBJECTIVE:To put forward the design strategy of fitness equipment control interface, for the special groups to use common fitness equipment comfortably and conveniently. METHODS:Based on the research of existing fitness equipment control interface, according to the usage habits and cognitive awareness of special groups on control interface, a new design strategy has been put forward using the general design method and ergonomics. RESULTS AND CONCLUSION:Based on the existing 45 kinds of exercise bikes, 84 kinds of running machines and 129 kinds of treadmil fitness equipments, we found that these equipments are designed for common users in the aspects of design and production process and control interface. Universal design is a design concept beyond the lack of capacity to meet the different needs of different populations, and designed products can reduce or even eliminate the difference in the ability of special populations and the general population in use. The new strategy makes design of fitness equipment control interface generalized and good man-machine interactive, which can meet the demand of the special groups and help them do fitness exercise to improve their health and body function.%背景:随着健身器材越来越普及的当代国情,关注的焦点也应该转移到老年人、残疾人等这些特殊群体对健身器材的使用上。  目的:提出健身器材控制界面通用化设计策略,以便于特殊人群能够舒适方便的使用普通健身器材。  方法:通过对现有健身器材控制界面的调查研究,结合特殊人群对控制界面的使用习惯和认知意识,

  3. 某型导弹发控设备自动测试系统设计%Design of missile inertial guidance equipment automatic test system

    Institute of Scientific and Technical Information of China (English)

    杨艾兵; 董洋; 林园; 彭伟

    2012-01-01

    阐述了某型导弹发控设备自动测试系统的设计思想、硬件组成和软件设计。系统采用基于网络数据采集卡的虚拟仪器结构,实现了对某型导弹发控设备的自动测试,具有较高的可靠性、可雏修性和良好的使用性。%This paper describes a type of missile launch and control equipment, automatic test system design, hardware components and software design. System uses a Web-based virtual instrument data acquisition card of the structure, the realization of a missile launch and control equipment, automatic test, with high reliability, maintainability and good usability.

  4. Redefinition of Space and Equipment in the Kindergarten and Involving the Children in the Process of Designing.

    Science.gov (United States)

    Bika, Anastasia

    This research examined the extent to which 2.5- to 5-year-old children in three Kindergarten classrooms in Thessaloniki, Greece could be taught about the use of classroom space and equipment. The study combined the theoretical perspectives of Piaget, Vygotsky, Bruner, and Frangos with the views of theater director Peter Brook. Mixed-age groups of…

  5. Constraint methods that accelerate free-energy simulations of biomolecules

    Energy Technology Data Exchange (ETDEWEB)

    Perez, Alberto [Laufer Center for Physical and Quantitative Biology, Stony Brook University, Stony Brook, New York 11794 (United States); MacCallum, Justin L. [Department of Chemistry, University of Calgary, Calgary, Alberta T2N 1N4 (Canada); Coutsias, Evangelos A. [Laufer Center for Physical and Quantitative Biology, Stony Brook University, Stony Brook, New York 11794 (United States); Department of Applied Mathematics, Stony Brook University, Stony Brook, New York 11794 (United States); Dill, Ken A. [Laufer Center for Physical and Quantitative Biology, Stony Brook University, Stony Brook, New York 11794 (United States); Department of Physics and Astronomy, Stony Brook University, Stony Brook, New York 11794 (United States)

    2015-12-28

    Atomistic molecular dynamics simulations of biomolecules are critical for generating narratives about biological mechanisms. The power of atomistic simulations is that these are physics-based methods that satisfy Boltzmann’s law, so they can be used to compute populations, dynamics, and mechanisms. But physical simulations are computationally intensive and do not scale well to the sizes of many important biomolecules. One way to speed up physical simulations is by coarse-graining the potential function. Another way is to harness structural knowledge, often by imposing spring-like restraints. But harnessing external knowledge in physical simulations is problematic because knowledge, data, or hunches have errors, noise, and combinatoric uncertainties. Here, we review recent principled methods for imposing restraints to speed up physics-based molecular simulations that promise to scale to larger biomolecules and motions.

  6. Constraint methods that accelerate free-energy simulations of biomolecules

    International Nuclear Information System (INIS)

    Atomistic molecular dynamics simulations of biomolecules are critical for generating narratives about biological mechanisms. The power of atomistic simulations is that these are physics-based methods that satisfy Boltzmann’s law, so they can be used to compute populations, dynamics, and mechanisms. But physical simulations are computationally intensive and do not scale well to the sizes of many important biomolecules. One way to speed up physical simulations is by coarse-graining the potential function. Another way is to harness structural knowledge, often by imposing spring-like restraints. But harnessing external knowledge in physical simulations is problematic because knowledge, data, or hunches have errors, noise, and combinatoric uncertainties. Here, we review recent principled methods for imposing restraints to speed up physics-based molecular simulations that promise to scale to larger biomolecules and motions

  7. Kinetic analysis of interaction between lipopolysaccharide and biomolecules

    Institute of Scientific and Technical Information of China (English)

    Fan YANG; Xiurong YANG

    2008-01-01

    Lipopolysaccharide (LPS) is a major compo-nent of the outer membrane of all gram-negative bacteria. It interacts with some biomolecules and triggers a toxic reaction. In this paper, we studied the interaction between LPS from Salmonella Minnesota and some biomolecules using a surface plasmon resonance (SPR) biosensor. Biomolecules were immobilized on a CM5 sensor chip using the amino coupling method and LPS was injected over the immobilized surfaces. The affinity constant KA of LPS with serum albumin, hemoglobin, chitosan and lysozyme was 2.36 × 107, 2.03 × 108,7.58×106, 2.82 × 104 L·mol-1, respectively. However, LPS could not interact with ferritin.

  8. Quantum chemistry and charge transport in biomolecules with superconducting circuits

    Science.gov (United States)

    García-Álvarez, L.; Las Heras, U.; Mezzacapo, A.; Sanz, M.; Solano, E.; Lamata, L.

    2016-01-01

    We propose an efficient protocol for digital quantum simulation of quantum chemistry problems and enhanced digital-analog quantum simulation of transport phenomena in biomolecules with superconducting circuits. Along these lines, we optimally digitize fermionic models of molecular structure with single-qubit and two-qubit gates, by means of Trotter-Suzuki decomposition and Jordan-Wigner transformation. Furthermore, we address the modelling of system-environment interactions of biomolecules involving bosonic degrees of freedom with a digital-analog approach. Finally, we consider gate-truncated quantum algorithms to allow the study of environmental effects. PMID:27324814

  9. Quantum chemistry and charge transport in biomolecules with superconducting circuits

    Science.gov (United States)

    García-Álvarez, L.; Las Heras, U.; Mezzacapo, A.; Sanz, M.; Solano, E.; Lamata, L.

    2016-06-01

    We propose an efficient protocol for digital quantum simulation of quantum chemistry problems and enhanced digital-analog quantum simulation of transport phenomena in biomolecules with superconducting circuits. Along these lines, we optimally digitize fermionic models of molecular structure with single-qubit and two-qubit gates, by means of Trotter-Suzuki decomposition and Jordan-Wigner transformation. Furthermore, we address the modelling of system-environment interactions of biomolecules involving bosonic degrees of freedom with a digital-analog approach. Finally, we consider gate-truncated quantum algorithms to allow the study of environmental effects.

  10. The increased safety level for structures, equipment and pipe networks by use of shock, vibration and seismic damping mechanical devices as per SERB -CITON design

    International Nuclear Information System (INIS)

    The paper presents SERB - SITON solution to reduce shocks, vibration and seismic movements in structures, pipe networks and equipment. The elimination or reduction of vibration is a difficult problem, still improperly handled theoretically and practically because the existing supports and dampers cannot provide a satisfactory damping for all the frequency ranges in the technical domain. The stiffness and damping of classic supports do not allow a good isolation against shocks and vibrations. In order to reduce the effects of vibrations with equipment and pipe network, this paper presents the results obtained by SITON on the concept, design, construction experimental testing and application of new types of supports called 'SERB Supports or devices'. These supports which include sandwich type elements, made up of elastic blade packages with distortions controlled by central and peripheral rigid parts are not affected by the aging phenomenon. The new types of supports may adjust themselves to the level of stress and distortion at overloading due to their non - linear geometric behavior while the contact pressure between the blades is limited to pre - set values. Due to their characteristics of adjustment to the actual position and level of stress, to the installation computation errors, the new supports show minimal effects on the pipe network and equipment stress condition. Herein below it is a presentation of the results obtained by SITON in the isolation of heavy equipment and pipe networks. (authors)

  11. Design and realization of test system for testing parallelism and jumpiness of optical axis of photoelectric equipment

    Science.gov (United States)

    Shi, Sheng-bing; Chen, Zhen-xing; Qin, Shao-gang; Song, Chun-yan; Jiang, Yun-hong

    2014-09-01

    With the development of science and technology, photoelectric equipment comprises visible system, infrared system, laser system and so on, integration, information and complication are higher than past. Parallelism and jumpiness of optical axis are important performance of photoelectric equipment,directly affect aim, ranging, orientation and so on. Jumpiness of optical axis directly affect hit precision of accurate point damage weapon, but we lack the facility which is used for testing this performance. In this paper, test system which is used fo testing parallelism and jumpiness of optical axis is devised, accurate aim isn't necessary and data processing are digital in the course of testing parallelism, it can finish directly testing parallelism of multi-axes, aim axis and laser emission axis, parallelism of laser emission axis and laser receiving axis and first acuualizes jumpiness of optical axis of optical sighting device, it's a universal test system.

  12. Design and Contruction Rules for Mechanical equipments of PWR islands: RCC-M. Tome 3: test methods

    International Nuclear Information System (INIS)

    This book is the 6th of a whole set of 7 ones which constitute the edition 1985 of the RCC-M. The present book deals with test methods: mechanical, physical, physico-chemical and chemical tests (tensile test, impact test, toughness test, folding test, flaring and flattening test, hardness test...; accelerated intergranular corrosion test, structure examination, measurement of the ferrite ratio, chemical composition control, test to estimate residual stresses in exchanger tubes); ultrasonic testing (equipments and modalities, examination of castings forgings, sheet metals, tubes, welded joints, coatings and platings); radiographic tests/equipments and processes, film processing, examination and quality, examination of castings and forgings and of welded joints); liquid penetrant testing (products used and processes, examination and interpretation, cleaning); magnetoscopic examinations (equipments and modalities, interpretation, cleaning and demagnetization, current passage test by means of portable electric control, magnetic flux passage test, and Eddy current testing for tubular elements); and several other examinations (visual, surface state, leak testing). The qualification and certification of non-destructif testing operators is finally dealt with

  13. 桨式路面清扫机的设计与研究%Design and Research of Paddle-type Road Pavement Cleaning Equipment

    Institute of Scientific and Technical Information of China (English)

    张云秀; 周建荣; 张宏

    2014-01-01

    随着城市道路的迅速增加以及对市容环境要求的不断提升,道路清扫工作越来越凸显其重要性,各式各样的清扫工具也应运而生。简要介绍了现有的清扫设备,并针对其不足,在考虑节能环保的大前提下,设计了一种由现有电动车改装的路面清扫机。该机由电瓶提供动力,结构简单,类似人工扫把清扫路面,将机械操作与人的主动性很好地结合起来,在减轻工人劳动强度的同时,兼顾了制作成本,是一种适合中小型道路清扫的新型设备。%With the rapid increase in the number of urban roads and higher requirements for urban appearance,road cleaning work has become increasingly important,various kinds of cleaning tools have appeared,existing cleaning equipment is introduced briefly,In view of the shortcomings of cleaning equipment,considering the national energy conservation and environmental protection,a kind of road pavement cleaning equipment developed from existing electric vehicles is designed. This equipment is battery-operated,with a simple structure,like a broom cleaning the road pavement,perfectly combining machine operation and initiative of people,it can not only reduce labor intensity of workers,but gives consideration to manufacturing cost,making it new equipment suitable for cleaning of small and medium-sized roads.

  14. Work Breakdown Structure and Plant/Equipment Designation System Numbering Scheme for the High Temperature Gas- Cooled Reactor (HTGR) Component Test Capability (CTC)

    Energy Technology Data Exchange (ETDEWEB)

    Jeffrey D Bryan

    2009-09-01

    This white paper investigates the potential integration of the CTC work breakdown structure numbering scheme with a plant/equipment numbering system (PNS), or alternatively referred to in industry as a reference designation system (RDS). Ideally, the goal of such integration would be a single, common referencing system for the life cycle of the CTC that supports all the various processes (e.g., information, execution, and control) that necessitate plant and equipment numbers be assigned. This white paper focuses on discovering the full scope of Idaho National Laboratory (INL) processes to which this goal might be applied as well as the factors likely to affect decisions about implementation. Later, a procedure for assigning these numbers will be developed using this white paper as a starting point and that reflects the resolved scope and outcome of associated decisions.

  15. 移动式放射性废液接收处理装置设计%Design of Mobile Receiving and Treatment Equipment for Radioactive Liquid Waste

    Institute of Scientific and Technical Information of China (English)

    孔劲松; 吕景彬; 郭卫群

    2012-01-01

    The advantage and disadvantage of radioactive liquid waste treatment technology are analyzed in this paper. The experimental disposal equipment for radioactive liquid waste with complicated sources is designed by combining the far infrared calefaction technology with evaporation technology. It has advantages of low energy consuming and high decontamination efficiency. The frothy and dirt appear rarely in this equipment.%分析多种放射性废液处理方法的优缺点,结合远红外辐射加热技术与蒸发处理技术,设计一套适合复杂源项废液的移动式接收处理的试验装置,该装置具有能耗低、去污效率高、不易起泡、不易结垢等特点.

  16. 21 CFR 225.30 - Equipment.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 4 2010-04-01 2010-04-01 false Equipment. 225.30 Section 225.30 Food and Drugs... Equipment § 225.30 Equipment. (a) Equipment which is designed to perform its intended function and is properly installed and used is essential to the manufacture of medicated feeds. Such equipment...

  17. Recovery of Biomolecules from Food Wastes — A Review

    Directory of Open Access Journals (Sweden)

    Antonietta Baiano

    2014-09-01

    Full Text Available Food wastes are produced by a variety of sources, ranging from agricultural operations to household consumption. About 38% occurs during food processing. At present, the European Union legislation encourages the exploitation of co-products. This valorisation can be achieved through the extraction of high-value components such as proteins, polysaccharides, fibres, flavour compounds, and phytochemicals, which can be re-used as nutritionally and pharmacologically functional ingredients. Extraction can proceed according to solid-liquid extraction, Soxhlet extraction, pressurized fluid extraction, supercritical fluid extraction, ultrasound-assisted extraction, microwave-assisted extraction, pulsed electric field extraction, and enzyme-assisted extraction. Nevertheless, these techniques cannot be used indiscriminately and their choice depends on the type of biomolecules and matrix, the scale processing (laboratory or industrial, the ratio between production costs and economic values of the compounds to be extracted. The vegetable wastes include trimmings, peelings, stems, seeds, shells, bran, residues remaining after extraction of oil, starch, sugar, and juice. The animal-derived wastes include wastes from bred animals, wastes from seafood, wastes from dairy processing. The recovered biomolecules and by-products can be used to produce functional foods or as adjuvants in food processing or in medicinal and pharmaceutical preparations. This work is an overview of the type and amounts of food wastes; food waste legislation; conventional and novel techniques suitable for extracting biomolecules; food, medicinal and pharmaceutical uses of the recovered biomolecules and by-products, and future trends in these areas.

  18. Solvation dynamics of biomolecules: modeling and terahertz experiments.

    Science.gov (United States)

    Leitner, David M; Gruebele, Martin; Havenith, Martina

    2008-12-01

    The role of water in biomolecule dynamics has attracted much interest over the past decade, due in part to new probes of biomolecule-water interactions and developments in molecular simulations. Terahertz (THz) spectroscopy, among the most recent experimental methods brought to bear on this problem, is able to detect even small solute induced changes of the collective water network dynamics at the biomolecule-water interface. THz measurements reveal that proteins influence up to 1000 water molecules in their surroundings, and that even small saccharides influence the dynamics of hundreds of surrounding water molecules. The THz spectrum of a protein is sensitive to mutation and depends on the surface charge and flexibility of the protein. Influence on the solvation shell appears most pronounced for native wildtype proteins and decreases upon partial unfolding or mutation. THz spectra of solvated saccharides reveal that the number of water molecules coupled dynamically to a saccharide, forming a dynamical hydration shell around it, is related to the number of exposed oxygen atoms on the solute. The thickness of this layer appears correlated with the bioprotection efficiency of the saccharide. All findings support the thesis of a long-range dynamic coupling between biomolecule and solvent. PMID:19436490

  19. Recovery of biomolecules from food wastes--a review.

    Science.gov (United States)

    Baiano, Antonietta

    2014-01-01

    Food wastes are produced by a variety of sources, ranging from agricultural operations to household consumption. About 38% occurs during food processing. At present, the European Union legislation encourages the exploitation of co-products. This valorisation can be achieved through the extraction of high-value components such as proteins, polysaccharides, fibres, flavour compounds, and phytochemicals, which can be re-used as nutritionally and pharmacologically functional ingredients. Extraction can proceed according to solid-liquid extraction, Soxhlet extraction, pressurized fluid extraction, supercritical fluid extraction, ultrasound-assisted extraction, microwave-assisted extraction, pulsed electric field extraction, and enzyme-assisted extraction. Nevertheless, these techniques cannot be used indiscriminately and their choice depends on the type of biomolecules and matrix, the scale processing (laboratory or industrial), the ratio between production costs and economic values of the compounds to be extracted. The vegetable wastes include trimmings, peelings, stems, seeds, shells, bran, residues remaining after extraction of oil, starch, sugar, and juice. The animal-derived wastes include wastes from bred animals, wastes from seafood, wastes from dairy processing. The recovered biomolecules and by-products can be used to produce functional foods or as adjuvants in food processing or in medicinal and pharmaceutical preparations. This work is an overview of the type and amounts of food wastes; food waste legislation; conventional and novel techniques suitable for extracting biomolecules; food, medicinal and pharmaceutical uses of the recovered biomolecules and by-products, and future trends in these areas. PMID:25232705

  20. Fullerene–biomolecule conjugates and their biomedicinal applications

    Directory of Open Access Journals (Sweden)

    Yang X

    2013-12-01

    Full Text Available Xinlin Yang,1 Ali Ebrahimi,1 Jie Li,1,2 Quanjun Cui11Orthopaedic Research Laboratory, Department of Orthopaedic Surgery, University of Virginia School of Medicine, Charlottesville, VA, USA; 2School of Materials Science, Beijing Institute of Technology, Beijing, People's Republic of ChinaAbstract: Fullerenes are among the strongest antioxidants and are characterized as "radical sponges." The research on biomedicinal applications of fullerenes has achieved significant progress since the landmark publication by Friedman et al in 1993. Fullerene–biomolecule conjugates have become an important area of research during the past 2 decades. By a thorough literature search, we attempt to update the information about the synthesis of different types of fullerene–biomolecule conjugates, including fullerene-containing amino acids and peptides, oligonucleotides, sugars, and esters. Moreover, we also discuss in this review recently reported data on the biological and pharmaceutical utilities of these compounds and some other fullerene derivatives of biomedical importance. While within the fullerene–biomolecule conjugates, in which fullerene may act as both an antioxidant and a carrier, specific targeting biomolecules conjugated to fullerene will undoubtedly strengthen the delivery of functional fullerenes to sites of clinical interest.Keywords: fullerene, amino acid, peptide, oligonucleotide, sugar, ester

  1. Database design on accounting treatment system for music equipment management%音乐器材管理账务处理系统数据库设计

    Institute of Scientific and Technical Information of China (English)

    吕欣鑫

    2014-01-01

    音乐教育是我国素质教育的重要组成部分,提高学生的音乐艺术素养,必须充分发挥音乐器材的重要作用。针对音乐器材账务难以管理的现状,本文进行数据库设计,为账务处理系统开发提供支持。以需求分析为基础,进行了概念结构设计和逻辑结构设计。需求分析采用UML进行用例建模,概念结构设计采用实体联系图表示,逻辑结构设计以转换规则为基础通过表格形式设计了3个表结构。%Music education is an important part of quality education,which can improve their music art accomplishment,so the important role of music equipment must be fully play.This paper studies database design in the light of the present situation of music equipment accounting difficult to manage to provide support for the development of accounting treatment system.Conceptual structure design and logical structure design should be carried on based on requirement analysis.Requirement analysis conducted use case modeling used UML;conceptual structure design was showed by the diagram of entity-relationship;logical structure design designed three table structures by the table form based on transformation rule.

  2. Meteorology Electronic Equipment Test and Network System Design%气象电子设备检修及网络系统设计

    Institute of Scientific and Technical Information of China (English)

    秦铁

    2009-01-01

    计算机技术和信息技术在我国气象业务中的开发与应用已日益广泛,在技术装备、技术方法和管理方法上具有传统气象所不具备的特点.针对气象电子设备的管理与维修方法进行论述,并对相应的通讯网络设计进行分析,该方法对了解和掌握设备检修和网络保障具有重要作用.%Computer and infermation technology had already developed and applied widely in our meteorology. It has some special features compared with traditional metorology as technology equipment, method and management way. The paper mainly discuss the management ancl repeir method of meterology electronic equipment, and analyze network design, it has great effect on equipment repair and network ensurence.

  3. 电子设备机箱电磁屏蔽分析和设计%Electronic Equipment Chassis Electromagnetic Shielding Analysis and Design

    Institute of Scientific and Technical Information of China (English)

    赵旭阳

    2012-01-01

    On the analysis of the electronic equipment working environment,and on the basis of the electronic equipment of external clear main interference source,and shielding effectiveness analysis.For improving Electronic Equipments' resist-disturbance capability,contraposing outside interference source,advance shielding filtering and ground and otherwise resist-disturbance design method,to insure Electronic Equipments can be working up to snuff in the condition of complex execrable war field EME.%在分析了电子设备工作环境的基础上,明确了电子设备外部的主要干扰源,并进行了屏蔽效能分析。为提高电子设备抗干扰性能,针对外部干扰源提出了屏蔽、滤波和接地等抗干扰设计方案,确保电子设备能在复杂恶劣的环境下正常工作。

  4. 矿山设备领域主题爬虫研究与设计%STUDYING AND DESIGNING TOPIC CRAWLER FOR MINING EQUIPMENTS FIELD

    Institute of Scientific and Technical Information of China (English)

    龚炳江; 黄彦欣; 贾海鑫

    2014-01-01

    通过对主题网络爬虫的研究,设计一个对网络中的矿山设备资源进行收集的主题网络爬虫。设计内容主要包括主题网络爬虫的各个功能模块以及各功能模块实现的方法。例如判定网页主题相关度及URL价值评价等。使用的主要技术为向量空间模型和PageRank算法。矿山设备领域主题网络爬虫的研究与设计为矿山设备领域主题爬虫的实现奠定了基础。%Through the research on topic web crawler, we design a topic web crawler which can collect the mining equipments resources in networks.The content of the design mainly includes each functional module of the topic web crawler and the method to realise these function modules.For example, to judge the correlation of webpage topics and the URL value evaluation, and so on.The main technology it used is the vector space model and the PageRank algorithm.The study and design of the topic crawler for mining equipments field lays a sound foundation for its implementation.

  5. Proceedings of the sixth international conference on material issues in design, manufacturing and operation of nuclear power plants equipment. Volume 2

    International Nuclear Information System (INIS)

    The papers reported at the 6-Th International conference Materials issues in design, manufacturing and operation of nuclear power plants equipment are presented. The emphasis is on the problem of structural integrity with taking account for reactor vessel irradiation. The problems of extension of service life for reactors of the first generation are under discussion. The most of papers deal with stainless, low alloy and carbon steel testing for fracture toughness, fatigue strength, resistance to stress-corrosion cracking in both base metal and welded joints

  6. Impact of design of installations and in the personal staff formation of the hybrid equipment: PET-CT

    International Nuclear Information System (INIS)

    In this article the general principles to be considered in the design of a Nuclear Medicine department with PET-CT, and address the existing problems regarding training needs and staff training, to take on this new technology

  7. Biomolecule-nanoparticle hybrids as functional units for nanobiotechnology.

    Science.gov (United States)

    Baron, Ronan; Willner, Bilha; Willner, Itamar

    2007-01-28

    Biomolecule-metal or semiconductor nanoparticle (NP) hybrid systems combine the recognition and catalytic properties of biomolecules with the unique electronic and optical properties of NPs. This enables the application of the hybrid systems in developing new electronic and optical biosensors, to synthesize nanowires and nanocircuits, and to fabricate new devices. Metal NPs are employed as nano-connectors that activate redox enzymes, and they act as electrical or optical labels for biorecognition events. Similarly, semiconductor NPs act as optical probes for biorecognition processes. Double-stranded DNA or protein chains that are modified with metallic nanoclusters act as templates for the synthesis of metallic nanowires. The nanowires are used as building blocks to assemble nano-devices such as a transistor or a nanotransporter.

  8. Antifouling self-assembled monolayers on microelectrodes for patterning biomolecules.

    Science.gov (United States)

    Noel, John; Teizer, Winfried; Hwang, Wonmuk

    2009-01-01

    We present a procedure for forming a poly(ethylene glycol) (PEG) trimethoxysilane self-assembled monolayer (SAM) on a silicon substrate with gold microelectrodes. The PEG-SAM is formed in a single assembly step and prevents biofouling on silicon and gold surfaces. The SAM is used to coat microelectrodes patterned with standard, positive-tone lithography. Using the microtubule as an example, we apply a DC voltage to induce electrophoretic migration to the SAM-coated electrode in a reversible manner. A flow chamber is used for imaging the electrophoretic migration and microtubule patterning in situ using epifluorescence microscopy. This method is generally applicable to biomolecule patterning, as it employs electrophoresis to immobilize target molecules and thus does not require specific molecular interactions. Further, it avoids problems encountered when attempting to pattern the SAM molecules directly using lithographic techniques. The compatibility with electron beam lithography allows this method to be used to pattern biomolecules at the nanoscale. PMID:19707178

  9. Models for Energy and Charge Transport, and Storage in Biomolecules

    CERN Document Server

    Mingaleev, S F; Gaididei, Yu B; Johansson, M; Rasmussen, K O; Mingaleev, Serge F.; Christiansen, Peter L.; Gaididei, Yuri B.; Johansson, Magnus; Rasmussen, Kim O.

    1999-01-01

    Two models for energy and charge transport and storage in biomolecules are considered. A model based on the discrete nonlinear Schrodinger equation with long-range dispersive interactions (LRI's) between base pairs of DNA is offered for the description of nonlinear dynamics of the DNA molecule. We show that LRI's are responsible for the existence of an interval of bistability where two stable stationary states, a narrow, pinned state and a broad, mobile state, coexist at each value of the total energy. The possibility of controlled switching between pinned and mobile states is demonstrated. The mechanism could be important for controlling energy storage and transport in DNA molecules. Another model is offered for the description of nonlinear excitations in proteins and other anharmonic biomolecules. We show that in the highly anharmonic systems a bound state of Davydov and Boussinesq solitons can exist.

  10. Research on lightweight design of airborne electronic equipments%机载电子装备轻量化设计初步研究

    Institute of Scientific and Technical Information of China (English)

    李雨; 魏强

    2014-01-01

    机载电子装备日益复杂化,飞机平台资源的有限性迫切要求其开展有效的轻量化工作。从系统顶层设计、总体布局、硬件设计、新型材料等方面论述了如何在机载电子装备研制过程中开展轻量化工作,对当前实际工程开展轻量化工作具有一定的指导意义。%With the increasing complication of airborne electronic equipments,the lightweight research is exigent due to the limitation of airborne space resource. The lightweight research in the process of airborne electronic equipment development is discussed in the aspects of system top-design,overall-layout,hardware design and new materials,which has a certain guiding significance for lightweight of the current engineering projects.

  11. Anthropometric study of farm workers on Java Island, Indonesia, and its implications for the design of farm tools and equipment.

    Science.gov (United States)

    Syuaib, M Faiz

    2015-11-01

    Anthropometric data are a prerequisite for designing agricultural tools and equipment that enable workers to achieve better performance and productivity while providing better safety and comfort. A set of thirty anthropometric dimensions was collected from a total sample of 371 male and female farm-workers from three different regions (west, central and east) of Java Island, Indonesia. The mean stature is 162.0 cm and 152.5 cm, the sitting height is 82.9 cm and 77.4 cm, and the body weight is 57.1 kg and 52.3 kg for male and female subjects, respectively. The index of relative sitting height (RSH) was 0.51 on average for both male and female subjects. Significant differences are found in most of the anthropometric dimensions between gender and regional data groups as well. Compared with groups of people from several other countries, the anthropometric dimensions of Indonesian people are quite similar to Indian people, but are relatively smaller than Filipino, Chinese, Japanese, British, and American people. An attempt was conducted to illustrate the use of this anthropometric database and ergonomic considerations in refining the design of traditional tools and equipment commonly in use for rice farming operations.

  12. Design of Electrical Training Equipment Control System Based on PLC%PLC电工实训装置控制系统设计

    Institute of Scientific and Technical Information of China (English)

    周飞; 张英琦

    2013-01-01

    以矿井提升绞车为模型,设计了一个基于PLC的电工实训装置,从功能上讲,主要由提升绞车模型、PLC电气控制系统、变频器变频调速系统、触摸屏监控系统组成。给出了系统方案,设计了PLC控制系统、信号检测电路和变频器控制电路。该实训装置突出“工矿”特色,既包括各种电气控制技术的基础实践训练,又包括多种电工技术的综合性实践训练。%Taking the mine hoist as model, electrical training equipment based on PLC is designed in the paper. From the func-tional point of view, the equipment is mainly composed of mine hoist model, PLC control system, inverter frequency control sys-tem and touch screen monitoring systems. The system scheme is proposed. The PLC control system, signal detection circuit and the inverter control system is designed. The training device outstanding industrial and mineral characteristic, including both vari-ous electric control technology foundation practice training, and variety of electrical technologies comprehensive practical train-ing.

  13. Structure, dynamics, and function of biomolecules

    Energy Technology Data Exchange (ETDEWEB)

    Frauenfelder, H.; Berendzen, J.R.; Garcia, A.; Gupta, G.; Olah, G.A.; Terwilliger, T.C.; Trewhella, J.; Wood, C.C.; Woodruff, W.H.

    1998-11-01

    This is the final report of a three-year, Laboratory Directed Research and Development (LDRD) project at the Los Alamos National Laboratory (LANL). The authors enhanced Los Alamos' core competency in Bioscience and Biotechnology by building on present strengths in experimental techniques, theory, high-performance computing, modeling, and simulation applied to biomolecular structure, dynamics, and function. Specifically, the authors strengthened their capabilities in neutron/x-ray scattering, x-ray crystallography, NMR, laser, and optical spectroscopies. Initially they focused on supporting the Los alamos Neutron Science Center (LANSCE) in the design and implementation of new neutron scattering instrumentation, they developed new methods for analysis of scattering data, and they developed new projects to study the structures of biomolecular complexes. The authors have also worked to strengthen interactions between theory and experiment, and between the biological and physical sciences. They sponsored regular meetings of members from all interested LANL technical divisions, and supported two lecture series: ''Biology for Physicists'' and ''Issues in Modern Biology''. They also supported the formation of interdisciplinary/inter-divisional teams to develop projects in science-based bioremediation and an integrated structural biology resource. Finally, they successfully worked with a multidisciplinary team to put forward the Laboratory's Genome and Beyond tactical goal.

  14. 装备采办数据资源管理流程总体设计%General Design of Equipment Acquisition Data Resource Management Process and Operation

    Institute of Scientific and Technical Information of China (English)

    许鹏文; 司远征

    2013-01-01

    According to the data management theory and model of American National Standards Institute (ANSI), this paper gives a general design of the basic process and operation of equipment acquisition data resources management with the method of IDEFO modeling, and subscribes the three key-steps, and the performance of this design.%依据美国国家标准协会(American National Standards Institute,ANSI)的数据管理理论与模型,采用IDEF0(ICAM(integrated computer aided manufacturing) definition method)建模的方法对装备采办数据资源管理的基本流程进行了总体设计,对流程中的3个关键步骤进行了阐述,最后描述了其运行方式.

  15. Immobilization of different biomolecules by atomic force microscopy

    Directory of Open Access Journals (Sweden)

    Hölzel Ralph

    2010-05-01

    Full Text Available Abstract Background Micrometer resolution placement and immobilization of probe molecules is an important step in the preparation of biochips and a wide range of lab-on-chip systems. Most known methods for such a deposition of several different substances are costly and only suitable for a limited number of probes. In this article we present a flexible procedure for simultaneous spatially controlled immobilization of functional biomolecules by molecular ink lithography. Results For the bottom-up fabrication of surface bound nanostructures a universal method is presented that allows the immobilization of different types of biomolecules with micrometer resolution. A supporting surface is biotinylated and streptavidin molecules are deposited with an AFM (atomic force microscope tip at distinct positions. Subsequent incubation with a biotinylated molecule species leads to binding only at these positions. After washing streptavidin is deposited a second time with the same AFM tip and then a second biotinylated molecule species is coupled by incubation. This procedure can be repeated several times. Here we show how to immobilize different types of biomolecules in an arbitrary arrangement whereas most common methods can deposit only one type of molecules. The presented method works on transparent as well as on opaque substrates. The spatial resolution is better than 400 nm and is limited only by the AFM's positional accuracy after repeated z-cycles since all steps are performed in situ without moving the supporting surface. The principle is demonstrated by hybridization to different immobilized DNA oligomers and was validated by fluorescence microscopy. Conclusions The immobilization of different types of biomolecules in high-density microarrays is a challenging task for biotechnology. The method presented here not only allows for the deposition of DNA at submicrometer resolution but also for proteins and other molecules of biological relevance that

  16. Spatially Controlled Covalent Immobilization of Biomolecules on Silicon Surfaces

    OpenAIRE

    Pavlovic, Elisabeth

    2003-01-01

    The work described in this thesis aims to achieving surface patterning through chemical activation of thiolated silicon oxide surfaces, resulting in a spatially controlled covalent immobilization of biomolecules with high resolution. Existing chemical methods to immobilize molecules on surfaces do not reach below the micrometer scale while the ones allowing for spatial control mostly lead to non-covalent adsorption of molecules on surfaces, or require several successive chemical reactions to ...

  17. Capillary Electrophoresis-based Methodology Development for Biomolecule Analysis

    OpenAIRE

    Li, Ni

    2011-01-01

    Capillary electrophoresis (CE) is a separation tool with wide applications in biomolecule analysis. Fast and high-resolution separation requiring minute sample volumes is advantageous to study multiple components in biological samples. Flexible modes and methods can be developed. In this thesis, I focus on developing and applying novel CE methods to study multi-target nucleic acid sensing with high sensitivity (Part I) and interactions between multiple components, i.e. proteins, nanoparticles...

  18. Mapping the Chemical Universe of Biomolecules for Astrobiology

    OpenAIRE

    Meringer, Markus

    2015-01-01

    Understanding the origins of life is a central question of Astrobiology. Computer methods offer unique means to approach this challenge. In order to obtain a better understanding of the selection rules which guided chemical and early biochemical evolution, our approach is to computationally generate exhaustive sets of biomolecule analogues, to calculate their physico-chemical properties, and to simulate adaptive processes that might have led to the biochemical foundations of life as we know i...

  19. The first search for glycine and other biomolecules

    OpenAIRE

    Storey, J. W. V.

    2012-01-01

    In the 1970s the microwave spectroscopy group at Monash University became the first in the world to determine the spectral frequencies of urea, glycine, and several other biomolecules. We immediately searched for these at Parkes, using existing centimetre-wave receivers plus newly built receivers that operated at frequencies as high as 75GHz (and used just the central 17 m of the dish). Although these searches were largely unsuccessful, they helped launch the now flourishing field of astrobio...

  20. Models and algorithms for biomolecules and molecular networks

    CERN Document Server

    DasGupta, Bhaskar

    2016-01-01

    By providing expositions to modeling principles, theories, computational solutions, and open problems, this reference presents a full scope on relevant biological phenomena, modeling frameworks, technical challenges, and algorithms. * Up-to-date developments of structures of biomolecules, systems biology, advanced models, and algorithms * Sampling techniques for estimating evolutionary rates and generating molecular structures * Accurate computation of probability landscape of stochastic networks, solving discrete chemical master equations * End-of-chapter exercises

  1. Models for Energy and Charge Transport and Storage in Biomolecules

    OpenAIRE

    Mingaleev, S. F.; Christiansen, P. L.; Gaididei, Yu. B.; M. Johansson; Rasmussen, K.Ø.

    1999-01-01

    Two models for energy and charge transport and storage in biomolecules are considered. A model based on the discrete nonlinear Schrodinger equation with long-range dispersive interactions (LRI's) between base pairs of DNA is offered for the description of nonlinear dynamics of the DNA molecule. We show that LRI's are responsible for the existence of an interval of bistability where two stable stationary states, a narrow, pinned state and a broad, mobile state, coexist at each value of the tot...

  2. Design of intelligent monitoring system for medical equipment%医疗设备智能监控系统的设计

    Institute of Scientific and Technical Information of China (English)

    赵明; 奚卫东

    2013-01-01

    Objective: Intelligent monitoring system of medical equipment can realize the intelligent dynamic management to equipment in the hospital wireless or wired network environment. Methods: Use of communication network, intelligent call, system monitoring and other means of science and technology to design the intelligent micro device state sensor. Results:System is mainly for hospital equipment, which can capture and management of medical equipment data. When the elderly have abnormal condition, it can send information through intelligent system, through identification and location, to realize the construction of equipment state information. Conclusion: Intelligent sensor in the system application can achieve the sharing of resources; realize the whole hand or full coverage of the intelligent health network system, providing an effective guarantee for the health of the masses.%目的:建立医疗设备智能监控系统,使医院在无线覆盖或有线网络的环境下,实现设备的智能化动态管理。方法:利用通讯网络、智能呼叫及系统监测等科技手段,设计医疗设备智能状态传感器。结果:针对医院医疗设备,将其数据进行采集和管理。当出现异常状况时可通过智能系统发出相关信息,通过身份识别与定位,实现设备状态的信息化。结论:智能传感器在系统的运用中可做到资源共享,实现了全方位、全覆盖的智能医院物联网系统,为医院的医疗服务提供了有效的保障。

  3. Applications of polymers for biomolecule immobilization in electrochemical biosensors

    International Nuclear Information System (INIS)

    Polymers are becoming inseparable from biomolecule immobilization strategies and biosensor platforms. Their original role as electrical insulators has been progressively substituted by their electrical conductive abilities, which opens a new and broad scope of applications. In addition, recent advances in diagnostic chips and microfluidic systems, together with the requirements of mass-production technologies, have raised the need to replace glass by polymeric materials, which are more suitable for production through simple manufacturing processes. Conducting polymers (CPs), in particular, are especially amenable for electrochemical biosensor development for providing biomolecule immobilization and for rapid electron transfer. It is expected that the combination of known polymer substrates, but also new transducing and biocompatible interfaces, with nanobiotechnological structures, like nanoparticles, carbon nanotubes (CNTs) and nanoengineered 'smart' polymers, may generate composites with new and interesting properties, providing higher sensitivity and stability of the immobilized molecules, thus constituting the basis for new and improved analytical devices for biomedical and other applications. This review covers the state-of-the-art and main novelties about the use of polymers for immobilization of biomolecules in electrochemical biosensor platforms

  4. Repulsive effects of hydrophobic diamond thin films on biomolecule detection

    Energy Technology Data Exchange (ETDEWEB)

    Ruslinda, A. Rahim, E-mail: ruslindarahim@gmail.com [Institute of Nano Electronic Engineering, Universiti Malaysia Perlis, Jln Kgr-Alor Setar, Seriab, 01000 Kangar, Perlis (Malaysia); Department of Nano Science and Nano Engineering, School of Advance Science and Engineering, Ohkubo 3-4-1, Shinjuku, 169-8555 Tokyo (Japan); Ishiyama, Y. [Department of Nano Science and Nano Engineering, School of Advance Science and Engineering, Ohkubo 3-4-1, Shinjuku, 169-8555 Tokyo (Japan); Penmatsa, V. [Department of Mechanical and Materials Engineering, Florida International University, 10555 West Flagler Street, Miami, FL 33174 (United States); Ibori, S.; Kawarada, H. [Department of Nano Science and Nano Engineering, School of Advance Science and Engineering, Ohkubo 3-4-1, Shinjuku, 169-8555 Tokyo (Japan)

    2015-02-15

    Highlights: • We report the effect of fluorine plasma treatment on diamond thin film to resist the nonspecific adsorption of biomolecules. • The diamond thin film were highly hydrophobic with a surface energy value of ∼25 mN/m. • The repulsive effect shows excellent binding efficiency for both DNA and HIV-1 Tat protein. - Abstract: The repulsive effect of hydrophobic diamond thin film on biomolecule detection, such as single-nucleotide polymorphisms and human immunodeficiency virus type 1 trans-activator of transcription peptide protein detection, was investigated using a mixture of a fluorine-, amine-, and hydrogen-terminated diamond surfaces. These chemical modifications lead to the formation of a surface that effectively resists the nonspecific adsorption of proteins and other biomolecules. The effect of fluorine plasma treatment on elemental composition was also investigated via X-ray photoelectron spectroscopy (XPS). XPS results revealed a fluorocarbon layer on the diamond thin films. The contact angle measurement results indicated that the fluorine-treated diamond thin films were highly hydrophobic with a surface energy value of ∼25 mN/m.

  5. Repulsive effects of hydrophobic diamond thin films on biomolecule detection

    International Nuclear Information System (INIS)

    Highlights: • We report the effect of fluorine plasma treatment on diamond thin film to resist the nonspecific adsorption of biomolecules. • The diamond thin film were highly hydrophobic with a surface energy value of ∼25 mN/m. • The repulsive effect shows excellent binding efficiency for both DNA and HIV-1 Tat protein. - Abstract: The repulsive effect of hydrophobic diamond thin film on biomolecule detection, such as single-nucleotide polymorphisms and human immunodeficiency virus type 1 trans-activator of transcription peptide protein detection, was investigated using a mixture of a fluorine-, amine-, and hydrogen-terminated diamond surfaces. These chemical modifications lead to the formation of a surface that effectively resists the nonspecific adsorption of proteins and other biomolecules. The effect of fluorine plasma treatment on elemental composition was also investigated via X-ray photoelectron spectroscopy (XPS). XPS results revealed a fluorocarbon layer on the diamond thin films. The contact angle measurement results indicated that the fluorine-treated diamond thin films were highly hydrophobic with a surface energy value of ∼25 mN/m

  6. 某机载电子设备总体结构设计%Structure Design of Airborne Electronic Equipment for a Certain Aircraft

    Institute of Scientific and Technical Information of China (English)

    南雁; 郭建平; 张娅妮

    2011-01-01

    从结构设计角度出发,根据航空平台的工作模式和环境空间要求,针对某机载电子设备的标准化设计、热设计、电磁兼容性设计、防冲击、振动、"三防"设计等方面进行了论述.结合型号设计的工程经验,以航空电子设备结构设计的特点和原则为重点,对机载电子设备的结构设计进行了阐述,通过合理的布局设计和仿真计算来实现结构设计要求.介绍机载电子设备结构设计的经验,可供同行参考.%From the point of structure design,according to work and environment requisition for the aircraft flat ,described delailed such as the standardization, heat, EMC,impact and vibration prevention,three proofing designing for a certain aircraft. Focus on the characteristic and principle for aeronauticat electronic equipment,expatiate the structure design from Many- sided ,and guidance thc structure design by logical position and simulation with engineering experience. Pool the experience for structure design and offer the experience for craft brother discuss.

  7. 低功耗水下通信系统设计%Design of Low Power Underwater Equipment Communication System

    Institute of Scientific and Technical Information of China (English)

    杨勃锋; 张效民; 祖翔宇

    2012-01-01

    The low power underwater equipment communication system is based on MSP430 MCU and the series of TMS32OC55x DSP. The MCU is in power state and monitors the communication control signal persistently in the system. The DSP is closed in no communicatioi time. Until the MCU receives communication instructions, the DSP is turned on after opening the power of DSP, then receives and decode the signal. After the DSP accomplishes communication and operates instructions, the DSP is turned off. The MCU detects the communicatioi control signal using sliding related method, and controls the power of DSP to start -up DSP. The experiments show that the system can ef fectively reduce the power, when the communication time ls 1% of the total time,The system can save 88.7% of the power.%设计了一种基于MSP430单片机和TMS320C55x系列DSP的低功耗水下通信系统,该系统中单片机一直处于上电状态,实时监测通信控制信号,在非通信时段DSP处于关机状态,单片机收到通信指令后,通过启动DSP电源启动DSP接收并解码通信信号,DSP完成通信并进行相关的指令操作后关机;单片机通过滑动相关方法检测通信控制信号,通过控制DSP电源启动关闭DSP,实验表明该系统能有效的降低功率,其中在通信时段占总时段1%的情况下,该系统能节省88.7%的功率.

  8. Simulation Using Novel Equipment Designed to Explain Spirometric Abnormalities in Respiratory Disease Enhances Learning in Higher Cognitive Domains

    Science.gov (United States)

    Jamison, J. P.; Stewart, M. T.

    2015-01-01

    Simulation of disorders of respiratory mechanics shown by spirometry provides insight into the pathophysiology of disease but some clinically important disorders have not been simulated and none have been formally evaluated for education. We have designed simple mechanical devices which, along with existing simulators, enable all the main…

  9. Design and testing of Ground Penetrating Radar equipment dedicated for civil engineering applications: ongoing activities in Working Group 1 of COST Action TU1208

    Science.gov (United States)

    Pajewski, Lara; Manacorda, Guido; Persico, Raffaele

    2015-04-01

    This work aims at presenting the ongoing research activities carried out in Working Group 1 'Novel GPR instrumentation' of the COST (European COoperation in Science and Technology) Action TU1208 'Civil Engineering Applications of Ground Penetrating Radar' (www.GPRadar.eu). The principal goal of the COST Action TU1208 is to exchange and increase scientific-technical knowledge and experience of GPR techniques in civil engineering, simultaneously promoting throughout Europe the effective use of this safe and non-destructive technique in the monitoring of infrastructures and structures. Working Group 1 (WG1) of the Action focuses on the development of innovative GPR equipment dedicated for civil engineering applications. It includes three Projects. Project 1.1 is focused on the 'Design, realisation and optimisation of innovative GPR equipment for the monitoring of critical transport infrastructures and buildings, and for the sensing of underground utilities and voids.' Project 1.2 is concerned with the 'Development and definition of advanced testing, calibration and stability procedures and protocols, for GPR equipment.' Project 1.3 deals with the 'Design, modelling and optimisation of GPR antennas.' During the first year of the Action, WG1 Members coordinated between themselves to address the state of the art and open problems in the scientific fields identified by the above-mentioned Projects [1, 2]. In carrying our this work, the WG1 strongly benefited from the participation of IDS Ingegneria dei Sistemi, one of the biggest GPR manufacturers, as well as from the contribution of external experts as David J. Daniels and Erica Utsi, sharing with the Action Members their wide experience on GPR technology and methodology (First General Meeting, July 2013). The synergy with WG2 and WG4 of the Action was useful for a deep understanding of the problems, merits and limits of available GPR equipment, as well as to discuss how to quantify the reliability of GPR results. An

  10. The design of vertical installation equipment for the piston rod production line%活塞杆竖直装挂进料装置的设计

    Institute of Scientific and Technical Information of China (English)

    杨振; 张艳冬; 刘占娟

    2015-01-01

    目前国内活塞杆电镀时的竖直装挂主要靠人工完成,劳动强度大,且效率低。针对某公司现有的活塞杆电镀挂具,进行了竖直装挂进料装置的设计,主要包括机械部分和控制系统。装置采用伺服电机和气压作为驱动,螺旋传动实现工作台移位,接近开关和控制伺服电机转动圈数定位方式相结合,实现多根活塞杆同时自动进给,降低了劳动强度,提高了工作效率。%At the present stage the main feed way to vertical installation of the piston rod is artificial and comple-ted.It not only needs high labor intensity, but also is low efficiency.Aiming at the electroplating production line with piston rod in a company, it introduces the design of vertical installation equipment such as mechanical and control system.The equipment uses the servo motor and air pressure as drive, moves the table by rotating the transmission shift.The position switch and servo motor realizes automatic feeding of several piston rods.This e-quipment can reduce the labor intensity and improve the work efficiency.

  11. Design of automatic control system for antigravity casting equipment%反重力铸造设备自动控制系统的设计

    Institute of Scientific and Technical Information of China (English)

    王艳珍; 邹蕾; 朱登飙

    2016-01-01

    According to the actual control needs of the antigravity casting equipment,an automatic control system for anti⁃gravity casting equipment was designed by means of modern automatic control technology. The overall design of the system,hard⁃ware selection and software design were accomplished. The digital PID control method is used to improve the system’s self⁃com⁃pensation ability and anti⁃interference ability. The Ziegler⁃Nichols method is used to set the digital PID parameters. The setting results were tested with the heat adjustment test. The test results show that the system has reliable operation,good curve tracking performance,and can achieve the application requirement.%根据反重力铸造设备实际控制的需要,运用现代自动控制技术设计一种反重力铸造设备自动控制系统,完成系统的总体设计、硬件选型与软件设计。运用数字PID控制方法对提高系统自补偿能力与抗干扰能力,通过Ziegler⁃Nichols方法对数字PID参数进行整定,对结果通过热调试验进行测试。结果表明,系统运行可靠,曲线跟踪性能良好,达到使用要求。

  12. 静态RCS测量雷达的设备布局及升降塔结构设计%Equipment Layout Design of Static RCS Measure Radar and Structure Design of Lift Tower

    Institute of Scientific and Technical Information of China (English)

    张兴唐; 李志兵; 马萍

    2012-01-01

    文中对静态RCS全频段测量雷达多天线和多收发设备的布局进行了设计,针对结构设计的核心部分——可移动高架天线塔进行了详细论述,对升降塔风栽荷进行了分析计算并用有限元法校核了天线塔身和天线安装架的强度,结果满足结构设计强度要求。解决了高架天线塔升降、天线安装调整、天线塔所装设备维修性和安全性的问题。对多波段静态RCS测量设备总体布局设计和高架升降塔的设计具有参考借鉴意义。%This paper designs the layout of antennas and T/R equipments for whole frequency bands static RCS measure radar. Detailed discussion is per formed for the mobile antenna tower which is the key part of structure design. Wind-load computing is carried out for the lift tower, the strength of antenna tower and an- tenna mounting structure is checked by finite element method, the results meet the design requirements. The problems of antenna going up and down, antenna stance adjusting, maintenance and security of equipments in antenna tower are solved in this paper. Study results of this paper are helpful to the layout design of multi- bands static RCS measure equipments and the structure design of lift tower.

  13. Disposable pen-shaped capillary gel electrophoresis cartridge for fluorescence detection of bio-molecules

    Science.gov (United States)

    Amirkhanian, Varoujan; Tsai, Shou-Kuan

    2014-03-01

    We introduce a novel and cost-effective capillary gel electrophoresis (CGE) system utilizing disposable pen-shaped gelcartridges for highly efficient, high speed, high throughput fluorescence detection of bio-molecules. The CGE system has been integrated with dual excitation and emission optical-fibers with micro-ball end design for fluorescence detection of bio-molecules separated and detected in a disposable pen-shaped capillary gel electrophoresis cartridge. The high-performance capillary gel electrophoresis (CGE) analyzer has been optimized for glycoprotein analysis type applications. Using commercially available labeling agent such as ANTS (8-aminonapthalene-1,3,6- trisulfonate) as an indicator, the capillary gel electrophoresis-based glycan analyzer provides high detection sensitivity and high resolving power in 2-5 minutes of separations. The system can hold total of 96 samples, which can be automatically analyzed within 4-5 hours. This affordable fiber optic based fluorescence detection system provides fast run times (4 minutes vs. 20 minutes with other CE systems), provides improved peak resolution, good linear dynamic range and reproducible migration times, that can be used in laboratories for high speed glycan (N-glycan) profiling applications. The CGE-based glycan analyzer will significantly increase the pace at which glycoprotein research is performed in the labs, saving hours of preparation time and assuring accurate, consistent and economical results.

  14. 智能变电站二次设备模块化设计技术%Modular Design of Secondary Equipment in Smart Substation

    Institute of Scientific and Technical Information of China (English)

    李宾皑; 翁之浩

    2016-01-01

    贯彻安全可靠、经济合理、技术先进、环境友好的技术原则,完成国家电网公司企业标准《模块化二次设备设计技术导则》的制定工作。结合模块化二次设备设计技术的相应研究成果,从模块定义与划分原则、模块技术要求、功能单元技术要求和模块布置要求4个方面解读主要条款的编制思路、基本原理以及注意事项。该标准能够大幅提高电气设备集成化水平,实现工厂工作量最大化、现场工作量最小化,可以大幅提高工程建设水平;所提出的模块化二次设备可促进国内厂家生产技术水平的提高,有效地节约社会资源,降低工程建设成本;对模块化二次设备设计作规定,填补国内空白,为智能变电站电气二次模块化设计提供重要依据。%To implement the engineering philosophy of security, reliability, reasonable economy, advanced technology and friendly environment, company standard of State Grid, “Technical specification for modularized secondary equipment” has been finished. Based on the corresponding research results of the modular secondary equipment design technology, the compiling thinking, basic principle and the matters needing attention of the main terms are explained from the four aspects of module definition and classification principles, module technical requirements, functional unit technical requirements and module layout. This standard can greatly improve the integration level of electrical equipment, and maximize factory work, minimize onsite workload, and can greatly improve the level of project construction as well. The modular secondary equipment proposed by this standard can greatly promote the level of production technology of domestic manufacturers, effectively save social resources, and reduce the cost of project construction. This standard can make rules for the design of modular secondary equipment, which fills in the home gaps, and

  15. Engineering Design of A Gang Drilling Machine Equipped with Jig and Fixtures to Make A Prototype Machine in Birdcage Production

    Directory of Open Access Journals (Sweden)

    Eddy Widiyono

    2011-11-01

    Full Text Available This paper is dealing with the engineering design of a gang drilling machine with jig & fixtures to make a prototype machine. This effort has been done in order to solve the problem which aroused in small business enterprises producing birdcages. The problem was how to minimize the production time in making a lot of holes that have same distance and straightness. Hopefully, the prototype machine can help the small business enterprises to increase their production rate.The design engineering process has been carried out by variant approximation on dowel pin modular fixtures in order to simplify fixtures design. CAD CAM software has also been used as fixtures synthesized method including geometric analysis and three dimensional fixtures assembling. The resulting prototype machine can be well operated and based on the running test, it can be concluded that the greater the motor rotation the greater the power needed. As for teak wood, at 250 rpm motor rotation the power needed is 26.5 watt, and at 400 rpm the motor needs power of 43.6 watt while at 600 rpm the motor needs power of 600 watt. The power consumption is also depends on the type of material, the better the mechanical properties of the materials, the higher the power consumption. For cast iron, the 400 rpm motor rotation needs power as high as 569.7 watt. This prototype of gang drilling machine needs power of 350 watt to make five holes on teak wood while ordinary drilling machine needs total power of 1350 watt.

  16. Design, construction and testing of replacement nuclear coolant pump stators to meet today's equipment reliability expectations

    Energy Technology Data Exchange (ETDEWEB)

    Fostier, L. [AREVA-Jeumont S.A. (France); Howell, D. [Duke Energy Corp., Charlotte, NC (United States)

    2005-07-01

    The continuous and reliable operation of nuclear power plants is critical to a utility's commercial bottom line. Many electric utilities with nuclear and other generating assets use non-nuclear generation to meet peak load and off-system power sales. Although motors installed during original construction have given fairly reliable service, the expectations in today's power generation market require that any improvements that could increase reliability should be used. This paper addressed the importance of reliability in a reactor coolant pump winding in a pressurized water reactor plant. The maintenance approach taken by one North American utility to avoid failure was presented. The challenges of the reactor coolant pump application was also discussed along with the improvements made in the winding design and construction. It was noted that the design margins incorporated into a reactor coolant pump motor will probably exceed those used for similar sized induction motors used for other industries due to the economic, radiological and nuclear safety concerns associated with an in service failure. As such, reactor coolant pump motors must meet special requirements based on the manufacturer experience, standards, electrotechnical standards and the customers request. The design of stators has resulted in improvements to address the following stress mechanisms: reduce thermal deterioration rate; inadequate resin bonding; loose windings; end winding corona; partial discharge; turn insulation stress or defects; and surface moisture and contamination. Validation testing was conducted on the replacement stator, including type tests on the initial stator and coils, in-process testing and final acceptance testing. All test results met the specified acceptance criteria. 7 refs., 2 tabs., 12 figs.

  17. Design and simulation of heat pumps and A/C equipment using pure and mixed refrigerants with MoMo (Modular Modelling)

    Energy Technology Data Exchange (ETDEWEB)

    Bensafi, A. [CETIAT, Centre Technique des Industries Aerauliques et Thermiques, 69 - Villeurbanne (France)

    1999-07-01

    An approach to the steady-state simulation of A/C, heat pumping and refrigerating equipment is presented. Novel features of the proposed model are the strategy and formalism adopted. Individual mathematical models for component design are dynamically linked to enable the simulation of a vapour compression cycle. This paper introduces some of the component modules, which can be used for pure as well as mixed refrigerants. Because numerous models can be used for specific pieces of equipment making up the whole refrigerating/heating unit, the Modular Modeling approach leads to a flexible and evolutive structure. The effects of operating conditions, refrigerant charge, or component geometrical parameters on cycle performance can then be examined. Because actual test data are used to 'calibrate' the component modules, very accurate results are obtained. The proposed model is validated with experimental results. Discrepancies smaller than 5% are obtained on the cooling duty and COP. An air conditioning unit using high pressure refrigerant R410A is optimised to illustrate the use of the model. (authors)

  18. 基于RCM的设备维修管理平台研究与开发%Research and Design of Equipment Maintenance Management Platform Based on RCM

    Institute of Scientific and Technical Information of China (English)

    徐丹; 吴俊

    2011-01-01

    以可靠性为中心的维修(Reliability-centered Maintenance,RCM)在设备维修方面有着重要意义.预防性维修是RCM的重要内容.该文在几种优化的预防性维修策略基础上,重点研究了周期预防性维修.根据经济性的原则,得出了装备最佳保养周期的计算方法,并用MATLAB仿真进行了验证.利用C#和MATLAB联合编程,设计出具有实用价值的设备可靠性维修管理平台.%It is significant for the research of reliability-centered maintenance(RCM) of communication equipment Preventive maintenance is the important content of RCM. Several optimization of the preventive maintenance strategy is discussed, especially the cycle preventive maintenance. According to the principle of economy, the best maintenance cycle is given and verified by MATLAB simulation. Equipment maintenance management platform is designed with C# and MATLAB for practice.

  19. Design of Wireless Control Device on Engineering Equipment%工程装备无线控制装置设计

    Institute of Scientific and Technical Information of China (English)

    李鹏; 赵建民

    2016-01-01

    In this paper, wireless control for the amphibious armored pavement operation could be realized by using the wire-less communication technology and the single-chip microcomputer control technology without changing the original circuit and structures of equipment.Through design of the wireless control system, it provides more control ways for the engineering e-quipments, improves the operation flexibility and operation efficiency, and offers worker with security assurance.%运用无线通信技术和单片机控制技术实现两栖装甲路面作业的无线控制,且不改变装备原有的电路和结构。通过设计无线控制系统,为工程装备提供更多的控制方式,提高了装备的作业灵活性和作业效率,同时也为作业手作业提供了安全保障。

  20. 机载塔康设备综合检查仪设计%Design of Integrated Tester for Airborne TACAN Equipment

    Institute of Scientific and Technical Information of China (English)

    曹乃森; 丁永强; 马贵兵

    2012-01-01

    使用市场上成熟的模块和技术研制机载塔康设备综合检查仪,以降低成本和提高设备的可靠性;根据设备的测试需求,选用嵌入式工业平板电脑、USB- ARINC429通讯卡、USB-数字IO卡、串行接口数字表和自研的塔康信号模拟器等构成检查仪硬件,使用CVI9.0编写了测试程序;应用表明:检查仪集成度高,使用方便,能够完成对塔康设备的自动及手动测试.%The integrated tester for airborne TACAN equipment is developed using mature modules and technology in market to decrease cost and increase reliability of tester. According to test requirment select embeded industry pad, USB-ARINC429 card, USB -digit IO card, serial digital multimeter and the designed TACAN signal simulator to construct hardware of tester and compile test program with CVI9. 0. The application shows that the tester has higher integration and can accomplish conveniently testment of equipment with automatic or hand test.

  1. Ash removal equipment of large power plants designed for increased brown coal ash content and for economic use of waste products

    Energy Technology Data Exchange (ETDEWEB)

    Neumann, G.; Nicko, K.H.; Weidlich, H.G.

    1984-12-01

    The design and performance of the pneumatic deashing system of a brown coal fired steam generator with 660 t/h steam capacity are explained. Experiments were carried out aimed at improving the performance of the pneumatic conveyor with its discontinuously working pressure vessel. A modified technology of operating the pneumatic system quasi-continuously was investigated, with which a 100% higher ash throughput, elimination of pipe clogging and a 40% reduction in air requirement were achieved. Equipment for loading ash from bunkers into closed container cars was further studied. Substantial steel wear was noted at the mixing screw of the ash moistening trough. A new ash moistening and mixing drum (4 m long, 1.8 m diameter, 20 kW drive) has been developed, capable of moistening 600 m/sup 3//h of ash with only 15% of the electrical energy and 30% of the maintenance expenditures of mixing screw equipment. The manufacturer, OBV Budapest, will produce 3 sizes of the new ash mixing drum for reconstruction of ash loading facilities at various power plants. 7 references.

  2. 一种康复设备医疗网络平台的设计%Design of the Medical Rehabilitation Equipment Network Platform

    Institute of Scientific and Technical Information of China (English)

    朱沪生; 喻洪流; 吴刘海

    2015-01-01

    This paper mainly introduces the design of the medical rehabilitation equipment network plat-form. Our goal is to realize digital management of hospital rehabilitation department,to integrate and control a vari-ety of rehabilitation equipments in the same platform and save the rehabilitation training data and finally to help doctors and patients communicate with multi platforms. The platform is constructed by using Struts2 + Spring + Hi-bernate(SSH)framework,and is implemented by using Java language,JSP technology,HTML language,JQuery plugin script technology and MySQL5 database technology.%该文主要介绍了一种康复设备医疗网络平台的设计,目标是实现医院康复科的数字化管理,集成多种康复设备于同一平台进行控制和保存训练数据,帮助医患双方实现多平台沟通。平台采用 Struts2+ Spring + Hibernate(SSH)架构,结合 Java 语言、JSP 技术、HTML 语言、JQuery 插件脚本技术和 MySQL5数据库技术对平台进行实现。

  3. 7 CFR 58.626 - Packaging equipment.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Packaging equipment. 58.626 Section 58.626 Agriculture....626 Packaging equipment. Packaging equipment designed to mechanically fill and close single service... Standards for Equipment for Packaging Frozen Desserts and Cottage Cheese. Quality Specifications for...

  4. Design of Assemble or Disassemble Equipment System Based on VR Technology%基于VR技术的设备拆装系统设计

    Institute of Scientific and Technical Information of China (English)

    胡畔; 姜睐; 李依桐

    2012-01-01

    To solve the problem of showing and virtually operating the assemble and disassemble process of the equipments,a VR(Virtual Reality) training system based on virtual reality technology in which students can assemble or disassemble equipments was designed by a new, simple and quick software solution of "modeling software + programming language". 3DMAX software are adopted to build the virtual training scenarios and virtual devices modeling, C programming language was used to achieve display the scene and model in real-time, produce special effects and interactive control function, ultimately complete the virtual device assemble or disassembly process. After the actual use of trainees, it show that the system has the characteristics of good interaction and strong immersion, the process of assemble or disassemble is realistic, efficient and convenient,achieved its purpose of assemble or disassemble e-quipments training, and it is a preparation and complement to assemble or disassemble actual equipments.%为解决在虚拟环境中对设备拆装过程进行演示和虚拟操作的问题,设计构建基于虚拟现实技术的设备拆装实训系统,给出一种新的、简单、快捷的软件解决方案,即“模型文件十开发包”的方法.用3DMAX实现虚拟实训场景及其中虚拟设备的建模,用VC编程实现场景及模型的实时显示、特殊效果产生、人机交互控制等功能,最终实现虚拟的设备拆装实训系统设计.受训者的实际使用表明,该系统具有良好的交互性和较强的沉浸感,拆装过程逼真、高效、便捷,达到了设备拆装实训教学的训练目的,是对实物拆装实训的有益准备和补充.

  5. Dynamic Equipment Account Management System Research and Design%设备动态台账管理系统研究和设计

    Institute of Scientific and Technical Information of China (English)

    冀树春; 曹培庆; 郝乾军; 黄伟岗; 韩光美

    2015-01-01

    研究电厂建设期和生产期设备的设计技术参数、安装调试记录、实验数据、运行日志、缺陷故障情况、巡检记录、部件情况、图纸技术资料等技术大数据,并对这些数据进行专业化的提取、统计、分析、共享、加工、关联、整合等,通过集成各个分生产管理信息系统的设备大数据,生成一套设备管理的专业综合数据信息系统,以便快速、有效、准确、系统地掌握各电厂设备运行情况,实现企业设备系统全生命运行状态的动态管理,提高企业生产运营的数字化管理水平及管理的时效性。%The paper studied the technical big-data of the power plant during construction period and production period such as equipment design technical parameters, installation and debugging records, experimental data, run logs, defect fault conditions, inspection records, case parts, drawings and other technical information, and systematic analyzes these data by specialization statistics, analysis, sharing, processing, correlation, integration, integrated device data, etc. By integrating device data for each of the production management information system, the authors generate a comprehensive set of professional equipment management information system which can fast, efficiently, accurately and systematically grasp of the operation situation of the power plant equipment, achieve a dynamic management of the whole life running state enterprise equipment systems, and improve the timeliness of the management level of digital production the operations and management of the power plant.

  6. 卧式连续生物炭炭化设备研制%Design and manufacture of horizontal continuous biomass carbonization equipment

    Institute of Scientific and Technical Information of China (English)

    袁艳文; 田宜水; 赵立欣; 姚宗路

    2014-01-01

    针对中国生物炭设备中存在的运行不稳定、炭产出率低、副产品回收利用难等问题,该文设计了卧式连续生物炭炭化设备,热解反应器采用双层套筒结构,内层为炭化室,内置螺旋输送机,外层为高温烟气套筒,利用炭化自身产生的高温烟气燃烧产生的热量进行炭化。选择了热解参数,开展了热工设计和可燃气燃烧器热计算,并对炭化室、高温烟气套筒等关键部件进行了结构设计。采用稻壳原料进行了炭化试验,试验结果表明,卧式连续炭化设备实现了连续稳定运行,炭化设备设计合理,原料适用性广,小时生产率为45kg/h,稻壳炭化终温为500℃,炭化得率质量分数为42%。实现了设计目标,提高了炭化得率,为中国生物炭产业的发展提供了理论基础和技术支持。%The burning of fossil fuels, the changes in agricultural and land utilization, as well as the industrial processes produce a lot of carbon dioxide and other greenhouse gases causing global warming. Climate increasingly has become one of the most far-reaching global environmental issues. The carbon can be stabilized by biochar for hundreds of years while the carbon element is very difficult to break down after mineralization. With the function of carbon sequestration and soil improvement in agriculture, it turns out to be one of the main ways to reduce carbon emissions in the future. Currently, the producing of biochar has become a hot topic both at home and abroad. In this paper, aiming at the existence of unstable operations, low percentage of biochar outputs, as well as the difficultly of recycling of by-products of China biochar, equipment designs of the horizontal equipment for continuous carbonization of biomass, which uses external thermal heating carbonization of feedstock. The difference requires an external heating fuel, the heat required for the dissertation utilizes the high temperature

  7. 卧式连续生物炭炭化设备研制%Design and manufacture of horizontal continuous biomass carbonization equipment

    Institute of Scientific and Technical Information of China (English)

    袁艳文; 田宜水; 赵立欣; 姚宗路

    2014-01-01

    The burning of fossil fuels, the changes in agricultural and land utilization, as well as the industrial processes produce a lot of carbon dioxide and other greenhouse gases causing global warming. Climate increasingly has become one of the most far-reaching global environmental issues. The carbon can be stabilized by biochar for hundreds of years while the carbon element is very difficult to break down after mineralization. With the function of carbon sequestration and soil improvement in agriculture, it turns out to be one of the main ways to reduce carbon emissions in the future. Currently, the producing of biochar has become a hot topic both at home and abroad. In this paper, aiming at the existence of unstable operations, low percentage of biochar outputs, as well as the difficultly of recycling of by-products of China biochar, equipment designs of the horizontal equipment for continuous carbonization of biomass, which uses external thermal heating carbonization of feedstock. The difference requires an external heating fuel, the heat required for the dissertation utilizes the high temperature and gas combustion-generated calorie to carbonize the raw materials., Combustion flue gas during start-up and insufficient supply combined with diesel auxiliary heating of the equipment, the pyrolytic reactor of which is double-layer structure, with the inner layer carbonization chamber equipped with the built-in screw conveyor while the out layer high-temperature flue sleeve, using the motor speed, to ensure the continuous feeding of material, mixing and uniform heat transfer to achieve a biological continuous production of charcoal and carbonization temperature-controlled. The reactor outer sleeve for the high temperature flue gas, the use of high temperature gas to heat biomass, and the outer cylinder has baffles and fins, extending the residence time of the flue gas, and increasing the heat transfer coefficient to achieve a sufficient heat exchange. The paper chooses

  8. 某装备蓄电池自动充电器的设计%The design of certain equipment, automatic battery charger

    Institute of Scientific and Technical Information of China (English)

    张宁

    2012-01-01

    Analysis is developed a battery charger automatic equipment of necessity,through to the battery charger scheme analysis and selection,design with pulse width modulation switch power supply,constant current charging control,constant pressure control as the main working model of automatic charger.%分析了研制某装备蓄电池自动充电器的必要性,通过对蓄电池充电器方案的分析与选取,设计出以脉宽调制开关电源、恒流充电控制、恒压控制为主要工作模式的自动充电器.

  9. Case study of a traditional material (adobe) for facilities design destined to X-ray equipment emplacement

    International Nuclear Information System (INIS)

    The objective of this work is to use the existent material (adobe) in the national market as an alternative for an optimum design that counts with the conditions for radiological protection as well as an adequate infrastructure to service assistance. Therefore, it gives a tool of professional use for an X-ray installation design, because the adobes represent an adequate protection for employees as Worker occupational exposed (WOE) and for general public, also for economics reasons and construction technical aspects. With the study of above material is demonstrated that in X-ray facilities construction is not always necessary the use of lead sheets or another materials for walls, which are used as shielding elements against ionizing radiation. The adobe election for this study, is because Bolivia counts with a great percentage of constructed areas whit this type of material because is economical and raw material is accessible for users. From the experimental tests we get the graphics that allow to found the half value thickness (HVT) of the half layer (HVL) of this adobe, is that thickness of material with when placed in the path of the radiation will attenuate it to one half its original value. A tenth value thickness (TVT) similarly reduces the radiation to one tenth of its original value. Material which contains heavy atoms and molecules such as steel and lead provide the most effective (thinnest) shields for X-rays. The contribute of this study, carried out with the construction material (adobe) that exists in the national market will be of great utility for society because there is no values recorded in the bibliography. (author)

  10. The Design of the Equipment Warehouse Visual Management Information System%器材仓库可视化管理信息系统设计

    Institute of Scientific and Technical Information of China (English)

    刘大伟; 刘克胜; 王铁宁; 梁波

    2011-01-01

    The EWMIS (equipment warehouse management in- formation system) has been used extensively, it greatly im-proved the operation efficiency of the store logistics and pro- moted the improvement of the management pattern as well as the business process optimization (BPO) of the Equipment Warehouse. Now one of its main research directions is the vi- sualization of management information. Based on this objective, the reform-design of the visualization of EWMIS is finished by using the technology of virtual reality, radio frequency identifi- cation (RFID), information visualization and UML, which can establish the foundation for the warehouse management and also offer some reference on the design of the visual management information system.%器材仓库管理信息系统在现代军事仓库物流领域的应用非常普遍,大幅提高了器材仓库物流作业效率,促进了器材仓库管理模式的改进和业务流程优化。目前其主要研究方向之一就是管理信息的可视化。文章正是基于这个目的,采取VR技术、RFID等技术和UML建模设计方法,实现了器材仓库可视化管理信息系统的改造设计,为器材仓库仓库管理水平的提升奠定了基础,也为可视化管理信息系统的设计提供了一定借鉴。

  11. Quantum Simulations of Solvated Biomolecules Using Hybrid Methods

    Science.gov (United States)

    Hodak, Miroslav

    2009-03-01

    One of the most important challenges in quantum simulations on biomolecules is efficient and accurate inclusion of the solvent, because the solvent atoms usually outnumber those in the biomolecule of interest. We have developed a hybrid method that allows for explicit quantum-mechanical treatment of the solvent at low computational cost. In this method, Kohn-Sham (KS) density functional theory (DFT) is combined with an orbital-free (OF) DFT. Kohn-Sham (KS) DFT is used to describe the biomolecule and its first solvation shells, while the orbital-free (OF) DFT is employed for the rest of the solvent. The OF part is fully O(N) and capable of handling 10^5 solvent molecules on current parallel supercomputers, while taking only ˜ 10 % of the total time. The compatibility between the KS and OF DFT methods enables seamless integration between the two. In particular, the flow of solvent molecules across the KS/OF interface is allowed and the total energy is conserved. As the first large-scale applications, the hybrid method has been used to investigate the binding of copper ions to proteins involved in prion (PrP) and Parkinson's diseases. Our results for the PrP, which causes mad cow disease when misfolded, resolve a contradiction found in experiments, in which a stronger binding mode is replaced by a weaker one when concentration of copper ions is increased, and show how it can act as a copper buffer. Furthermore, incorporation of copper stabilizes the structure of the full-length PrP, suggesting its protective role in prion diseases. For alpha-synuclein, a Parkinson's disease (PD) protein, we show that Cu binding modifies the protein structurally, making it more susceptible to misfolding -- an initial step in the onset of PD. In collaboration with W. Lu, F. Rose and J. Bernholc.

  12. Design, Synthesis, and Biological Evaluation of New Cathepsin B-Sensitive Camptothecin Nanoparticles Equipped with a Novel Multifuctional Linker.

    Science.gov (United States)

    Zhang, Xuan; Tang, Kaiyong; Wang, Hong; Liu, Yaqian; Bao, Bin; Fang, Yanfen; Zhang, Xiongwen; Lu, Wei

    2016-05-18

    Traditional antitumor drugs such as camptothecin and paclitaxel derivatives are widely used in cancer chemotherapy. However, the major defects of those agents include severe toxicity and poor water solubility. With these in mind, a novel multifunctional linker was designed and two Cathepsin B (CTB) sensitive CPT conjugates (9a and 9b) were synthesized. Through click chemistry, additional functional group mPEG2000 can be easily introduced into these conjugates. The introduction of mPEG2000 fragment resulted in the formation of nanoparticles 1a and 1b (average particle sizes were 216.9 and 257.9 nm, respectively) with significantly increased water solubility (more than 19 000-fold). The release of therapeutic drug SN-38 in the presence of CTB was confirmed by HPLC and prodrug 1a showed potent in vitro cytotoxicity against all tested cell lines. Impressively, compared with irinotecan, CTB sensitive prodrug 1a displayed similar in vivo efficacy with remarkable decreased in vivo toxicity. PMID:27070848

  13. Low-energy electron scattering from molecules, biomolecules and surfaces

    CERN Document Server

    Carsky, Petr

    2011-01-01

    Since the turn of the 21st century, the field of electron molecule collisions has undergone a renaissance. The importance of such collisions in applications from radiation chemistry to astrochemistry has flowered, and their role in industrial processes such as plasma technology and lighting are vital to the advancement of next generation devices. Furthermore, the development of the scanning tunneling microscope highlights the role of such collisions in the condensed phase, in surface processing, and in the development of nanotechnology.Low-Energy Electron Scattering from Molecules, Biomolecule

  14. Chemical tags for site-specific fluorescent labeling of biomolecules.

    Science.gov (United States)

    Freidel, Christoph; Kaloyanova, Stefka; Peneva, Kalina

    2016-06-01

    This review focuses on the various approaches to covalently attach a chromophore to a biomolecule of interest in site-specific manner. Novel methods like inverse electron-demand Diels-Alder reaction, Pictet-Spengler ligation and enzyme tags like SNAP and Halo-tags are critically discussed and compared to established techniques like copper-free click reaction and native chemical ligation. Selected examples in which the tags have been exploited for in vitro or in vivo imaging are reviewed and evaluated. PMID:26969255

  15. Detection of prostate-specific antigen with biomolecule-gated AlGaN/GaN high electron mobility transistors

    International Nuclear Information System (INIS)

    In order to improve the sensitivity of AlGaN/GaN high electron mobility transistor (HEMT) biosensors, a simple biomolecule-gated AlGaN/GaN HEMT structure was designed and successfully fabricated for prostate specific antigen (PSA) detection. UV/ozone was used to oxidize the GaN surface and then a 3-aminopropyl trimethoxysilane (APTES) self-assembled monolayer was bound to the sensing region. This monolayer serves as a binding layer for attachment of the prostate specific antibody (anti-PSA). The biomolecule-gated AlGaN/GaN HEMT sensor shows a rapid and sensitive response when the target prostate-specific antigen in buffer solution was added to the antibody-immobilized sensing area. The current change showed a logarithm relationship against the PSA concentration from 0.1 pg/ml to 0.993 ng/ml. The sensitivity of 0.215% is determined for 0.1 pg/ml PSA solution. The above experimental result of the biomolecule-gated AlGaN/GaN HEMT biosensor suggested that this biosensor might be a useful tool for prostate cancer screening. (paper)

  16. Identification of Biomolecular Building Blocks by Recognition Tunneling: Stride towards Nanopore Sequencing of Biomolecules

    Science.gov (United States)

    Sen, Suman

    DNA, RNA and Protein are three pivotal biomolecules in human and other organisms, playing decisive roles in functionality, appearance, diseases development and other physiological phenomena. Hence, sequencing of these biomolecules acquires the prime interest in the scientific community. Single molecular identification of their building blocks can be done by a technique called Recognition Tunneling (RT) based on Scanning Tunneling Microscope (STM). A single layer of specially designed recognition molecule is attached to the STM electrodes, which trap the targeted molecules (DNA nucleoside monophosphates, RNA nucleoside monophosphates or amino acids) inside the STM nanogap. Depending on their different binding interactions with the recognition molecules, the analyte molecules generate stochastic signal trains accommodating their "electronic fingerprints". Signal features are used to detect the molecules using a machine learning algorithm and different molecules can be identified with significantly high accuracy. This, in turn, paves the way for rapid, economical nanopore sequencing platform, overcoming the drawbacks of Next Generation Sequencing (NGS) techniques. To read DNA nucleotides with high accuracy in an STM tunnel junction a series of nitrogen-based heterocycles were designed and examined to check their capabilities to interact with naturally occurring DNA nucleotides by hydrogen bonding in the tunnel junction. These recognition molecules are Benzimidazole, Imidazole, Triazole and Pyrrole. Benzimidazole proved to be best among them showing DNA nucleotide classification accuracy close to 99%. Also, Imidazole reader can read an abasic monophosphate (AP), a product from depurination or depyrimidination that occurs 10,000 times per human cell per day. In another study, I have investigated a new universal reader, 1-(2-mercaptoethyl)pyrene (Pyrene reader) based on stacking interactions, which should be more specific to the canonical DNA nucleosides. In addition

  17. Novel in Vitro Efficiency of Chitosan Biomolecule Against Trichomonas Gallinae

    Directory of Open Access Journals (Sweden)

    SH Pourseyed

    2012-02-01

    Full Text Available Background: Development of new natural agents for parasitic diseases treatment has unexpectedly increased to overcome effectively against emergence and re-emergence of parasitic diseases, the appearance of drug resistant organisms and toxic side effects of current agents. The aim of the study was to evaluate antiprotozoal activities of chitosan biomolecule on trophozoites of Trichomonas gallinae.Methods: The antitrichomonal activity of various low molecular weight chitosan concentrations including 125, 250, 500 and 1250 μg ml-1 against T. gallinae trophozoites cultured in trypticase-yeast extract-maltose medium supplemented with heat-inactivated cold horse serum was evaluated in vitro. Samples containing medium without chitosan were also assayed as controls.Results: The mortality rates at 0, 3 and 6 h post treatment with all concentrations were significantly different from control group (P<0.05. Treated trophozoites showed more susceptibility to the highest concentration reaching mortality rate of 100% at 3h post inoculation. However, at this time, results for 125, 250 and 500 μg ml-1 were 93%, 95% and 96.7%, respectively.Conclusion: The results demonstrate that the application of chitosan biomolecule is a promising option for treatment of trichomoniasis in pigeons.

  18. Biosurfactants: Multifunctional Biomolecules of the 21st Century

    Directory of Open Access Journals (Sweden)

    Danyelle Khadydja F. Santos

    2016-03-01

    Full Text Available In the era of global industrialisation, the exploration of natural resources has served as a source of experimentation for science and advanced technologies, giving rise to the manufacturing of products with high aggregate value in the world market, such as biosurfactants. Biosurfactants are amphiphilic microbial molecules with hydrophilic and hydrophobic moieties that partition at liquid/liquid, liquid/gas or liquid/solid interfaces. Such characteristics allow these biomolecules to play a key role in emulsification, foam formation, detergency and dispersal, which are desirable qualities in different industries. Biosurfactant production is considered one of the key technologies for development in the 21st century. Besides exerting a strong positive impact on the main global problems, biosurfactant production has considerable importance to the implantation of sustainable industrial processes, such as the use of renewable resources and “green” products. Biodegradability and low toxicity have led to the intensification of scientific studies on a wide range of industrial applications for biosurfactants in the field of bioremediation as well as the petroleum, food processing, health, chemical, agricultural and cosmetic industries. In this paper, we offer an extensive review regarding knowledge accumulated over the years and advances achieved in the incorporation of biomolecules in different industries.

  19. Biosurfactants: Multifunctional Biomolecules of the 21st Century.

    Science.gov (United States)

    Santos, Danyelle Khadydja F; Rufino, Raquel D; Luna, Juliana M; Santos, Valdemir A; Sarubbo, Leonie A

    2016-01-01

    In the era of global industrialisation, the exploration of natural resources has served as a source of experimentation for science and advanced technologies, giving rise to the manufacturing of products with high aggregate value in the world market, such as biosurfactants. Biosurfactants are amphiphilic microbial molecules with hydrophilic and hydrophobic moieties that partition at liquid/liquid, liquid/gas or liquid/solid interfaces. Such characteristics allow these biomolecules to play a key role in emulsification, foam formation, detergency and dispersal, which are desirable qualities in different industries. Biosurfactant production is considered one of the key technologies for development in the 21st century. Besides exerting a strong positive impact on the main global problems, biosurfactant production has considerable importance to the implantation of sustainable industrial processes, such as the use of renewable resources and "green" products. Biodegradability and low toxicity have led to the intensification of scientific studies on a wide range of industrial applications for biosurfactants in the field of bioremediation as well as the petroleum, food processing, health, chemical, agricultural and cosmetic industries. In this paper, we offer an extensive review regarding knowledge accumulated over the years and advances achieved in the incorporation of biomolecules in different industries. PMID:26999123

  20. On biomolecules and semiconductors: Analytical studies of interface dynamics

    Science.gov (United States)

    Slavin, John William Joseph

    The studies discussed here were undertaken to examine the use of III-V semiconducting materials as templates for biomolecules, to be applied in such technologies as Field-Effect Transistor (FET) and Light-emitting Diode (LED) biosensors. Materials application requires an informed analysis of interactions between chemical environments. Specific to surfaces, this means investigating the molecular interactions between the substrate and the bonding moieties. The analytical tools used to probe these interactions, and the changes that such communication causes on specific substrates are specifically discussed. Surface analysis tools included in this review are Atomic Force Microscopy (AFM), Nanoindentation, X-ray Photoelectron Spectroscopy (XPS), and Raman Microscopy. The interaction of biomolecules - deoxyribonucleic acid (DNA), proteins adhered to nanoparticles, and amino acids - on semiconductor surfaces is also examined. Proper investigation follows, as well, the methods of applying these biomolecular structures to the specified surfaces, through procedures such as solution phase transfer, as well as Dip-pen Nanolithography (DPN). The stretching and enzymatic cleavage of DNA, on silicon oxide surfaces, was studied to determine the recognition properties of dual-enzymatic systems on surfaces. Fundamental questions such as the interaction of functional groups with InAs(100) surfaces, the mechanical properties of protein modified systems, and the DPN application of biologically relevant linker molecules to InAs(100) surfaces were explored. These studies provide information applicable to the development of novel sensing platforms in the future.

  1. 基于Zigbee技术的智能教室设备控制系统设计%Smart Classroom Equipment Control System Design Based on Zigbee Technology

    Institute of Scientific and Technical Information of China (English)

    陈海松

    2013-01-01

    随着生活水平的提高及科技进步,智能控制得到越来越广泛的应用。现有教室的灯光、窗帘、风扇等大都是采用手动控制或采用遥控器通过无线射频信号进行控制。文章将ZigBee无线通信技术应用到智能教室设备控制系统的设计中,给出了智能教室设备控制无线网络系统的总体方案和各部分软硬件的设计,并实现用户通过手机或平板电脑以无线Wifi的形式发送控制信号至无线路由器,控制信号经网线到以太网模块后发送至Zigbee模块,Zigbee模块接收控制信号后实现对Zigbee设备的控制。%With the improvement of living standards and the progress of science and technology, intelligent control has been more widely used. The existing classroom lighting, curtains, fans, etc. are controlled based on manual control or remote controller through RF signal. In this paper Zigbee wireless communication technology is applied in the design of the control system design of smart classroom equipment, the overall scheme and various hardware and software designs of the smart classroom equipment control wireless network system are given, and the transmission of the control signal to wireless router is implemented through mobile phone or tablet in Wifi form. The control signal is sent to the Zigbee module through cable to the Ethernet module, and the Zigbee module realizes the control of Zigbee devices by receiving control signal.

  2. Design for coating curing equipment based on short-wave radiation heating%涂层短波强辐射固化设备的设计

    Institute of Scientific and Technical Information of China (English)

    于喜年; 刘军; 赵月红

    2012-01-01

    In the surface painting industry, the application of shortwave radiation heating technology to workpiece surface coating curing system can shorten curing time, enhance energy use efficiency, reduce energy consumption, and improve the coating quality on workpiece surface. In this article, the principle of radiation heating technology is introduced. The essential difference between shortwave radiation heating and convection-conduction heating, as well as the rule for temperature control in the chamber of curing equipment were analyzed. The main components of coating shortwave radiation curing equipment and the design essentials were discussed. The chamber skeleton, radiation heater, and the structure of wind-reversed cycle system were studied.%在表面涂装领域,工件表面涂层固化系统采用短波强辐射固化技术可以缩短涂层固化时间,有效提高热能利用效率,减少能量消耗,提高工件表面涂装质量.本文介绍了强辐射加热技术的原理,分析了短波强辐射加热与对流-传导加热的本质区别以及固化设备室体内温度的控制规律,论述了涂层短波强辐射固化设备的主要组成部分和设计要点,研究了室体骨架、强辐射加热器和微风逆循环系统的结构.

  3. OCPN装备综合保障工作流引擎设计%Workflow Modeling and Engine Design of Equipment Integrated Logistic Support Based on IOCPN

    Institute of Scientific and Technical Information of China (English)

    杨军; 于永利

    2011-01-01

    针对装备综合保障工作流建模要求,构建了对象有色Petri网(Object-Oriented Colored Petri Net,OCPN)模型,给出该模型的形式化定义.结合装备使用过程综合保障工作,建立基于OCPN的工作流模型.根据工作流的执行过程,进行了工作流引擎体系结构以及相关类的设计,为工作流模型的计算机化以及工作流管理系统设计与实现提供了一种新的思路.%For the requirements of Integrated Logistic Support (ILS) workflow modeling, Object-Oriented Colored Petri Net (OCPN) model is built and its formal definition is given. Combining with business processes of ILS in equipment operational phase, its workflow model based on OCPN is built. Workflow engine based on OCPN is designed based on analyzing its performing process, including engine structure and correlative classes. It provides a new thought of computerizing workflow model, designing and implementing workflow management system.

  4. 面向紧急救援的搜救装备产品设计人性化考量%Considerations of Search and Rescue Equipment Product Humanized Design for Emergency Rescue

    Institute of Scientific and Technical Information of China (English)

    钱洪伟

    2015-01-01

    In this paper, the humanized product design preliminary definition of the concept, design, product design, humanization and search and rescue equipment product design humanization, etc.; Architecture of the search and rescue equipment product design problem: the logic of human interpretation interpretation of search and rescue equipment product design humanized nature, characteristics and functions; Based on dynamicexpounds “technology” , build the implementing mechanism of search and rescue equipment humanized product design; And proved by actual case. Studies have shown that the emergency rescue equipment in the product design process is integrated into the human factors, such as efficiency, security, risk factors, directly affect the rescue equipment when using relief effect; Product design if you don ’t consider modularity, removable, etc, in the event of accident, how to product of involved has been put into use forcible entry directly affect the relief progress; This study has important theoretical significance for deepening the research on design philosophy, to guide the search and rescue equipment humanized product design has strong practical significance.%本文对产品设计人性化的相关概念进行了初步的界定:设计、产品设计、人性化以及搜救装备产品设计人性化等;架构了搜救装备产品设计人性化的逻辑阐释问题:诠释了搜救装备产品设计人性化的本质;基于“技术动态过程论“思想,构建了搜救装备产品设计人性化的实现机制。研究表明:应急搜救装备在产品设计环节是否融入人性化因素,如工效、安全风险因素,直接影响救援装备使用时的救灾效果;产品设计时如果不考虑模块化、可拆卸等功能,一旦发生事故,如何对所涉已投入使用的产品进行破拆都直接影响救灾进度。本研究对于深化设计哲学研究具有重要的理论意义,对于引导搜救装备产品设

  5. Nuclear Weapon and Military Equipment

    Directory of Open Access Journals (Sweden)

    N. Natarajan

    1985-10-01

    Full Text Available Military equipment must survive a, nuclear attack if enough personnel required to operate them remain combat effective. To achieve this goal, the criteria that determine equipment survivability should be established and any new design should incorporate these criteria to evolve a hardened design. An analysis of the overall response by considering the response to each individual nuclear environment can result in a balanced overall hardened system. The paper discusses the criteria required to be known.

  6. 基于 Raspberry Pi的α能谱测量装置设计%Design of Alpha Spectrum Measurement Equipment Based on Raspberry Pi

    Institute of Scientific and Technical Information of China (English)

    李文涛; 唐泉; 吴淼; 李连山; 崔爽; 龙慧佳; 冯旭

    2015-01-01

    The paper proposed a design program of αembedded alpha spectrum measurement device based on Raspberry Pi computer.Based on Linux operating system and the Python program, the device realized the re-moteαspectral measurement, real-time display and data storage.Avoiding the operating system migration and driver development in general embedded system development, this design shortens the development period, and the software is compatible with the personal computer and windows operating system.The content includes hard-ware circuit scheme,alpha spectral acquisition board,data transmission and cross platform multithreading spec-trum software design.Tested through the Am -241 source, the repeatability and stability of the measurement equipment meet the requirements.%提出了一种基于Raspberry Pi计算机的嵌入式α能谱测量装置的设计方案,基于Linux操作系统和Python语言编写程序,并利用无线网络远程控制,实现了远程α能谱测量、实时显示和数据保存等功能,软件设计过程避免了操作系统迁移、驱动开发等工作,具有开发周期短,通用于PC机的特点。内容包括α能谱仪的硬件电路、数据传输和跨平台多线程能谱软件的设计。使用241 Am源对测量系统主要性能进行了测试,重复性及稳定性符合要求。

  7. Improved design and research of an installation and alignment equipment%一种装校设备的改进设计与研究

    Institute of Scientific and Technical Information of China (English)

    谢志江; 马伟; 倪卫; 刘小波

    2012-01-01

    The ORU installation and alignment equipment is a special device which is used to install the optics components on the large-scale laser device. Because the inside of the large-scale laser device is invisible for the operator, the problems such as interfer-ence and collision have been caused. Aiming at these major prob-lems, an improved scheme to add a 6-DOF F/T sensor was pro-posed, the establishment idea was demonstrated and the dynamic model was built and analyzed. The interference test was carried out on the prototype to validate the improved design with the curves of force and displacement-pose. The result of the test indicates that the improved design of ORU installation equipment is feasible with the resolving of the main problems existed in the prototype. The level of automation was improved with the purpose of flexible instal-lation approved.%ORU装校设备是用于将光学元件安装在大型激光装置上的专用设备.针对因大型激光装置内部对操作人员来说是盲区所带来的干涉、碰撞等主要问题,提出在ORU装校设备上新增六维力和力矩传感器的改进设计方案,阐述构建思路,建立了动力学模型并加以分析.在装校设备样机上进行干涉试验,得到力及位姿曲线,对改进设计方案进行验证.试验结果表明,ORU装校设备的改进设计方案是可行的,解决了样机中存在的主要问题,提高了装校设备的自动化程度,达到了柔性装校的目的.

  8. Cleaning supplies and equipment

    Science.gov (United States)

    ... gov/ency/patientinstructions/000443.htm Cleaning supplies and equipment To use the sharing features on this page, ... to clean supplies and equipment. Disinfecting Supplies and Equipment Start by wearing the right personal protective equipment ( ...

  9. A photocleavable affinity tag for the enrichment of alkyne-modified biomolecules

    NARCIS (Netherlands)

    Koopmans, Timo; Dekker, Frank J.; Martin, Nathaniel I.

    2012-01-01

    A new photocleavable affinity tag for use in the enrichment of alkyne-labelled biomolecules is reported. The tag is prepared via a concise synthetic route using readily available materials. The photolytic conditions employed for cleavage of the tag provide for a clean release of enriched biomolecule

  10. High-Speed AFM Reveals the Dynamics of Single Biomolecules at the Nanometer Scale

    NARCIS (Netherlands)

    Katan, A.J.; Dekker, C.

    2011-01-01

    Atomic force microscopy allows visualization of biomolecules with nanometer resolution under physiological conditions. Recent advances have improved the time resolution of the technique from minutes to tens of milliseconds, meaning that it is now possible to watch single biomolecules in action in re

  11. Sustained delivery of biomolecules from gelatin carriers for applications in bone regeneration

    NARCIS (Netherlands)

    Song, J.; Leeuwenburgh, S.C.G.

    2014-01-01

    Local delivery of therapeutic biomolecules to stimulate bone regeneration has matured considerably during the past decades, but control over the release of these biomolecules still remains a major challenge. To this end, suitable carriers that allow for tunable spatial and temporal delivery of biomo

  12. Equipment Design of Electrochemical Bearizing Processing Device%电解扩孔成形加工装置的设计

    Institute of Scientific and Technical Information of China (English)

    张京超; 田明鑫; 徐文骥; 刘新

    2015-01-01

    目前对细长孔进行扩孔加工主要采用机械扩孔的加工方法,存在刀杆易振动、加工轴线易歪斜等问题;而采用电解扩孔方法,则加工精度高、表面质量好,能较好地解决上述问题。设计并搭建的细长孔脉冲电解扩孔成形加工装置为细长阶梯孔脉冲电解扩孔加工奠定了实验条件。%At present,mechanical processing method is the principal method to process slender holes,but many problems exit in this method. For example,the tool is short of rigidity and machining axis is skewed. The machining accuracy and surface quality is good in pulse electrochemical bearizing processing. The pulse electrochemical bearizing machining equipment for slender holes is designed and built. These laid the experimental conditions of pulse electrochemical bearizing for slender holes.

  13. Synthesis of selenium nanorods with assistance of biomolecule

    Indian Academy of Sciences (India)

    S Kannan; K Mohanraj; K Prabhu; S Barathan; G Sivakumar

    2014-12-01

    Nanorods of one-dimensional (1D) trigonal selenium (t-Se) are synthesized using biomolecule substances for five different aging times (1 h, 2 h, 3 h, 1 day and 4 days) by precipitation method. XRD analysis indicates a shift of the (1 0 1) plane towards higher diffraction angle for 1 day aging time. It is observed that the crystallite size decreases with increase in aging time except for an aging period of 4 days. FTIR analysis confirmed that the presence of stretching and bending vibrations of Se–O in both synthesized and commercial selenium samples at 465, 668 and 1118 cm-1. The FESEM micrographs are evident for the changes of rod size as a function of aging time. It is observed that the optical band gap energy is increased with aging time up to 1 day, whereas it decreases in 4 days aging time.

  14. Interactions of model biomolecules. Benchmark CC calculations within MOLCAS

    Energy Technology Data Exchange (ETDEWEB)

    Urban, Miroslav [Slovak University of Technology in Bratislava, Faculty of Materials Science and Technology in Trnava, Institute of Materials Science, Bottova 25, SK-917 24 Trnava, Slovakia and Department of Physical and Theoretical Chemistry, Faculty of Natural Scie (Slovakia); Pitoňák, Michal; Neogrády, Pavel; Dedíková, Pavlína [Department of Physical and Theoretical Chemistry, Faculty of Natural Sciences, Comenius University, Mlynská dolina, SK-842 15 Bratislava (Slovakia); Hobza, Pavel [Institute of Organic Chemistry and Biochemistry and Center for Complex Molecular Systems and biomolecules, Academy of Sciences of the Czech Republic, Prague (Czech Republic)

    2015-01-22

    We present results using the OVOS approach (Optimized Virtual Orbitals Space) aimed at enhancing the effectiveness of the Coupled Cluster calculations. This approach allows to reduce the total computer time required for large-scale CCSD(T) calculations about ten times when the original full virtual space is reduced to about 50% of its original size without affecting the accuracy. The method is implemented in the MOLCAS computer program. When combined with the Cholesky decomposition of the two-electron integrals and suitable parallelization it allows calculations which were formerly prohibitively too demanding. We focused ourselves to accurate calculations of the hydrogen bonded and the stacking interactions of the model biomolecules. Interaction energies of the formaldehyde, formamide, benzene, and uracil dimers and the three-body contributions in the cytosine – guanine tetramer are presented. Other applications, as the electron affinity of the uracil affected by solvation are also shortly mentioned.

  15. Vacuum foam drying: An alternative to lyophilization for biomolecule preservation

    Directory of Open Access Journals (Sweden)

    R D Jangle

    2012-01-01

    Full Text Available Vacuum foam drying is evaluated as an alternative for lyophilization for enhanced process and storage stability of bovine serum albumin. The protein protective efficiency of different stabilizers was compared in vacuum foam drying and lyophilization. Sucrose mixtures produced better foam characters than mannitol. Unlike calcium lactate, incorporation of polyvinyl pyrrolidone to sucrose synergistically enhanced the recovery of bovine serum albumin. The conformational stability and bovine serum albumin content further increased with sodium phosphate as compared to potassium phosphate. All sucrose mixtures, except calcium lactate showed large α-helix amide-I band at approximately 1656 cm -1 . The amorphous powder diffraction in case of sodium phosphate monobasic mixture retained maximum bovine serum albumin content. The crystallization of similar mixtures in lyophilization reduced its bovine serum albumin content. Vacuum foam drying showed better processing and storage stability of bovine serum albumin than lyophilization process. Hence vacuum foam drying is short, simple and industrially economical process for biomolecules preservation.

  16. Efficient extraction strategies of tea (Camellia sinensis) biomolecules.

    Science.gov (United States)

    Banerjee, Satarupa; Chatterjee, Jyotirmoy

    2015-06-01

    Tea is a popular daily beverage worldwide. Modulation and modifications of its basic components like catechins, alkaloids, proteins and carbohydrate during fermentation or extraction process changes organoleptic, gustatory and medicinal properties of tea. Through these processes increase or decrease in yield of desired components are evident. Considering the varied impacts of parameters in tea production, storage and processes that affect the yield, extraction of tea biomolecules at optimized condition is thought to be challenging. Implementation of technological advancements in green chemistry approaches can minimize the deviation retaining maximum qualitative properties in environment friendly way. Existed extraction processes with optimization parameters of tea have been discussed in this paper including its prospects and limitations. This exhaustive review of various extraction parameters, decaffeination process of tea and large scale cost effective isolation of tea components with aid of modern technology can assist people to choose extraction condition of tea according to necessity.

  17. Recent Advances in Protein Extraction and Chiral Separation of Biomolecules

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    Reverse micelles create unique environment in organic media. They are capable of solubilizing hydrophilic biomolecules (e.g., proteins, peptides, amino acids, and DNAs) in their aqueous interior. This feature brings about the practical use of biomaterials in organic media because reverse micelles solubilize them with the intrinsic activity. In this paper, we focus on recent two topics concerning protein extraction and chiral separation of biomolecules using liquid membranes. In the first topic, we present recent attempts to extract proteins from an aqueous solution into isooctane using reverse micelles, and some important operational parameters to achieve an efficient protein transfer are discussed. Furthermore, novel function of reverse micelles as a protein activation medium is introduced. In the reverse micellar phase, denatured proreins were completely reactivated in the reverse micellar solution. The reverse micellar technique is found to be a useful tool not only for protein separation but also for protein refolding. Furthermore, we found that a cyclic ligand carixarene has an extraction ability to set up optimum conditions for protein transfer. In the second topic, we have found that a supported liquid membrane (SLM) encapsulating enzymes shows high enantioselectivity (enantioselective excess value is over 96%) in the transport of racemic pharmaceutical compound ibuprofen. A different experiment also suggests that the α-chymotrypsin-catalyzed reactions droved the enantioselective transport of L-phenylalanine based on the enantioselectivity of the enzyme. The SLM encapsulating the surfactant-enzyme complex enabled the highly enantioselective separation of racemic mixtures. It can be envisioned that arrangement of appropriate enzymes in the SLM system will allow enantioselective separation of various useful organic compounds.

  18. Platinum(II) complexes as spectroscopic probes for biomolecules

    Energy Technology Data Exchange (ETDEWEB)

    Ratilla, E.

    1990-09-21

    The use of platinum(II) complexes as tags and probes for biomolecules is indeed advantageous for their reactivities can be selective for certain purposes through an interplay of mild reaction conditions and of the ligands bound to the platinum. The use of {sup 195}Pt NMR as a method of detecting platinum and its interactions with biomolecules was carried out with the simplest model of platinum(II) tagging to proteins. Variable-temperature {sup 195}Pt NMR spectroscopy proved useful in studying the stereodynamics of complex thioethers like methionine. The complex, Pt(trpy)Cl{sup +}, with its chromophore has a greater potential for probing proteins. It is a noninvasive and selective tag for histidine and cysteine residues on the surface of cytochrome c at pH 5. The protein derivatives obtained are separable, and the tags are easily quantitated and differentiated through the metal-to-ligand charge transfer bands which are sensitive to the environment of the tag. Increasing the pH to 7.0 led to the modification by Pt(trpy)Cl{sup +}of Arg 91 in cytochrome c. Further studies with guanidine-containing ligands as models for arginine modification by Pt(trpy)Cl{sup +} showed that guanidine can act as a terminal ligand and as a bridging ligand. Owing to the potential utility of Pt(trpy)L{sup n+} as electron dense probes of nucleic acid structure, interactions of this bis-Pt(trpy){sup 2+} complex with nucleic acids was evaluated. Indeed, the complex interacts non-covalently with nucleic acids. Its interactions with DNA are not exactly the same as those of its precedents. Most striking is its ability to form highly immobile bands of DNA upon gel electrophoresis. 232 refs.

  19. 电动汽车电池箱检测工装的结构设计%Structure Design of Battery Box Test Equipment of Electric Car

    Institute of Scientific and Technical Information of China (English)

    崔庆东; 丁丽平; 郭炎杰; 李明道

    2013-01-01

    T he current electric vehicle battery boxes are made of manual inspection and have no battery or load block w hen detectingin the actual situation .In case of this ,this article presents a fully automatic battery box testing equipmentand a detailed statement of the test fixture design process and the typical program .By ana-lysing the advantages and disadvantages of the various options ,it ultimately designs a generic battery box testing automation equipment in this article .T he device implements the electric vehicle battery box automatic testing and evaluation ,w hich can not only reduce the labors intensity ,improve the reliability of the product testing ,credibility and the pre -qualified rate of battery box ,but also greatlyimprove the working efficiency and fill the gap of the industry .%针对目前电动汽车动力电池箱均采用人工检测且检测时不匹配电池或载重块的实际情况,提出了一种全自动化的电池箱检测工装,并详细陈述了检测工装的设计过程及典型方案,通过分析各个方案的优缺点,最终设计出了一种通用的自动化电池箱检测工装;该检测工装实现了电动汽车电池箱自动化检测与评估,不仅减轻了工人的劳动强度,提高了产品检测的可靠性、可信性和电池箱出厂合格率,工作效率也得到了很大的提升,为行业填补了空白。

  20. Oxidative destruction of biomolecules by gasoline engine exhaust products and detoxifying effects of the three-way catalytic converter.

    Science.gov (United States)

    Blaurock, B; Hippeli, S; Metz, N; Elstner, E F

    1992-01-01

    Aqueous solutions of engine exhaust condensation products were derived from cars powered by diesel or four-stroke gasoline engines (with and without three-way catalytic converter). The cars were operated on a static test platform. Samples of the different exhaust solutions accumulated in a Grimmer-type distillation trap (VDI 3872) during standard test programs (Federal Test Procedure) were incubated with important biomolecules. As indicators of reactive oxygen species or oxidative destruction, ascorbic acid, cysteine, glutathione, serum albumin, the enzymes glycerinaldehyde phosphate dehydrogenase and xanthine oxidase, and the oxygen free-radical indicator keto-methylthiobutyrate were used. During and after the incubations, oxygen activation (consumption) and oxidative destruction were determined. Comparison of the oxidative activities of the different types of exhaust condensates clearly showed that the exhaust condensate derived from the four-stroke car equipped with a three-way catalytic converter exhibited by far the lowest oxidative and destructive power. PMID:1283938

  1. Equipment Obsolescence Management Program

    Energy Technology Data Exchange (ETDEWEB)

    Redmond, J.

    2014-07-01

    Nuclear Power Plant (NPP) Operators are challenged with securing reliable supply channels for safety related equipment due to equipment obsolescence. Many Original Equipment Manufacturers (OEMs) have terminated production of spare parts and product life-cycle support. The average component life cycles are much shorter than the NPP design life, which means that replacement components and parts for the original NPP systems are not available for the complete design life of the NPPs. The lack or scarcity of replacement parts adversely affects plant reliability and ultimately the profitability of the affected NPPs. This problem is further compounded when NPPs pursue license renewal and approval for plant-life extension. A reliable and predictable supply of replacement co components is necessary for NPPs to remain economically competitive and meet regulatory requirements and guidelines. Electrical and I and C components, in particular, have short product life cycles and obsolescence issues must be managed pro actively and not reactively in order to mitigate the risk to the NPP to ensure reliable and economic NPP operation. (Author)

  2. Scientific Equipment Division - Overview

    International Nuclear Information System (INIS)

    Full text: The Scientific Equipment Division consists of the Design Group and the Mechanical Workshop. The activity of the Division includes the following: - designing of devices and equipment for experiments in physics, their mechanical construction and assembly. In particular, there are vacuum chambers and installations for HV and UHV; - maintenance and upgrading of the existing installations and equipment in our Institute; - participation of our engineers and technicians in design works, equipment assembly and maintenance for experiments in foreign laboratories. The Design Group is equipped with PC-computers and AutoCAD graphic software (release 2000 and Mechanical Desktop 4.0) and a AO plotter, what allows us to make drawings and 2- and 3-dimensional mechanical documentation to the world standards. The Mechanical Workshop can offer a wide range of machining and treatment methods with satisfactory tolerances and surface quality. It offers the following possibilities: - turning - cylindrical elements of a length up to 2000 mm and a diameter up to 400 mm, and also disc-type elements of a diameter up to 600 mm and a length not exceeding 300 mm; - milling - elements of length up to 1000 mm and gear wheels of diameter up to 300 mm; - grinding - flat surfaces of dimensions up to 300 mm x 1000 mm and cylindrical elements of a diameter up to 200 mm and a length up to 800 mm; - drilling - holes of a diameter up to 50 mm; - welding - electrical and gas welding, including TIG vacuum-tight welding; - soft and hard soldering; - mechanical works including precision engineering; - plastics treatment - machining and polishing using diamond milling, modelling, lamination of various shapes and materials, including plexiglas, scintillators and light-guides; - painting - paint spraying with possibility of using furnace-fred drier of internal dimensions of 800 mm x 800 mm x 800 mm. Our workshop posses CNC milling machine which can be used for machining of work-pieces up to 500 kg

  3. On-chip micro-electromagnets for magnetic-based bio-molecules separation

    Energy Technology Data Exchange (ETDEWEB)

    Ramadan, Qasem E-mail: qasem@pmail.ntu.edu.sg; Samper, Victor; Poenar, Daniel; Yu Chen

    2004-10-01

    This paper reports a comprehensive theoretical, finite element and measurement analysis of different designs of planar micro-electromagnets for bio-molecular manipulation. The magnetic field due to current flowing in complex shapes of current-carrying conductors have been calculated analytically, simulated using finite-element analysis (FEA), and measured using the superconducting quantum interference device technique (SQUID). A comparison of the theoretical and measured magnetic field strength and patterns is presented. The planar electromagnets have been fabricated using patterned Al 2 {mu}m thick. The aim of the study is to explore and optimize the geometrical and structural parameters of planar electromagnets that give rise to the highest magnetic fields and forces for magnetic micro-beads manipulation. Magnetic beads are often used in biochemical assays for separation of bio-molecules. Typical beads are 0.2-10 {mu}m in diameter and have superparamagnetic properties. Increasing the intensity of the magnetic field generated by a coil by injection a larger current is not the most suitable solution as the maximum current is limited by Joule heating. Consequently, in order to maximize the field for a given current, one should optimize the geometry of the coil, as this is an extremely significant factor in determining the magnetic field intensity in 2D planar designs. The theoretical and measured results of this work show that the meander micro-electromagnet with mesh-shaped winding profile produces the strongest magnetic field (about 2.7 {mu}T for a current intensity of 6 mA) compared with other meander designs, such as the serpentine and rosette-shaped ones. The magnetic fields of these three types of meander-shaped micro-electromagnets were compared theoretically with that produced by a spiral micro-electromagnet whose technological realization is more complicated and costly due to the fact that it requires an additional insulation layer with a contact window and

  4. 民政专用纳米光催化空气净化消毒机的设计与实现%Design and implementation of civil administration dedicated nano-TiO2 photocatalytic air antiseptic equipment

    Institute of Scientific and Technical Information of China (English)

    李秉杰; 王志良; 李伯森; 张培昆; 刘冀伟; 孟浩

    2013-01-01

    In order to reduce the air pollution discharged by funeral parlor of civil administration section during the funeral processes ,special antiseptic equipment was developed to purify the in-door air .Based on the filter technology ,activated carbon adsorption technology and photo-cata-lytic technology ,an intellectualized air flow control system was designed applying the modified chaos algorithm and PID optimal control algorithm .Then the prototype equipment was built at the optimal parameters .As shown by the experimental results ,the designed nano-TiO2 photo-catalytic antiseptic equipment is easy to operate and has a powerful antiseptic ability .This equip-ment can satisfyingly disinfect the air ,and therefore can replace the ultraviolet antiseptic equip-ment in the funeral parlor .%  为解决民政行业殡仪场所空气污染问题,研制了一种专用于殡仪场所空气净化的消毒机。以滤网过滤技术、活性炭吸附技术、纳米光催化技术为设计基础,应用改进混沌优化算法与智能PID 最优控制算法设计了智能风面控制系统,优化设计了空气消毒机的结构参数,最后制作样机。结果表明,设计的纳米TiO2光催化空气净化消毒机具有良好的消毒能力且操作简便,对环境空气具有良好的消毒净化功能,可替代紫外线用于殡仪场所空气净化和消毒。

  5. Development of manufacturing equipment and QC equipment for DUPIC fuel

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Myung Seung; Park, J.J.; Lee, J.W.; Kim, S.S.; Yim, S.P.; Kim, J.H.; Kim, K.H.; Na, S.H.; Kim, W.K.; Shin, J.M.; Lee, D.Y.; Cho, K.H.; Lee, Y.S.; Sohn, J.S.; Kim, M.J

    1999-05-01

    In this study, DUPIC powder and pellet fabrication equipment, welding system, QC equipment, and fission gas treatment are developed to fabricate DUPIC fuel at IMEF M6 hot cell. The systems are improved to be suitable for remote operation and maintenance with the manipulator at hot cell. Powder and pellet fabrication equipment have been recently developed. The systems are under performance test to check remote operation and maintenance. Welding chamber and jigs are designed and developed to remotely weld DUPIC fuel rod with manipulators at hot cell. Remote quality control equipment are being tested for analysis and inspection of DUPIC fuel characteristics at hot cell. And trapping characteristics is analyzed for cesium and ruthenium released under oxidation/reduction and sintering processes. The design criteria and process flow diagram of fission gas treatment system are prepared incorporating the experimental results. The fission gas treatment system has been successfully manufactured. (Author). 33 refs., 14 tabs., 91 figs.

  6. 基于Prolog语言的装备维修决策专家系统设计与开发%The Design and Development for Equipment Maintenance Decision-Making Expert System Based on Prolog Language

    Institute of Scientific and Technical Information of China (English)

    王广彦; 胡起伟; 王亚彬

    2012-01-01

    The equipment maintenance decision-making expert system is designed and developed based on Prolog intelligent language. The characteristics of equipment maintenance experts are researched thoroughly from the sides of maintenance knowledge and inferential ability. The basic syntaxes and inferential formats of expert system based on Prolog are analyzed, as well as their applications in equipment maintenance. The element knowledge database, correlative knowledge database, and application knowledge database are designed and developed for equipment maintenance decision-making expert system. At last a equipment maintenance decision-making expert system is developed through combinatorial programming of Visual Prolog and VC++.%采用Prolog智能语言对装备维修决策专家系统进行了设计与开发。从维修知识和推理能力两方面研究了装备维修专家的基本特点;分析了基于Prolog的专家系统的基本语法、推理方式及其在装备维修中的应用方式;设计并开发了装备维修决策专家系统的元知识库、关联知识库和应用知识库;最后采用Visual Prolog和VC++混合编程方式开发了某装备维修决策专家系统。

  7. 7 CFR 51.58 - Equipment.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Equipment. 51.58 Section 51.58 Agriculture Regulations... Requirements for Plants Operating Under Continuous Inspection on A Contract Basis § 51.58 Equipment. All equipment used for receiving, washing, grading, packaging or storing shall be of such design, material...

  8. 14 CFR 23.1451 - Fire protection for oxygen equipment.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Fire protection for oxygen equipment. 23... Equipment Miscellaneous Equipment § 23.1451 Fire protection for oxygen equipment. Oxygen equipment and lines... in, or escape from, any designated fire zone. (c) Be installed so that escaping oxygen cannot come...

  9. Proceedings of FED remote maintenance equipment workshop

    International Nuclear Information System (INIS)

    A workshop was convened in two sessions in January and March 1981, on the remote maintenance equipment for the Fusion Engineering Device (FED). The objectives of the first session were to familiarize the participants with the status of the design of the FED and to develop a remote maintenance equipment list for the FED. The objective of the second session was to have the participants present design concepts for the equipment which had been identified in the first session. The equipment list was developed for general purpose and special purpose equipment. The general purpose equipment was categorized as manipulators and other, while the special purpose equipment was subdivided according to the reactor subsystem it serviced: electrical, magnetic, and nuclear. Both mobile and fixed base manipulators were identified. Handling machines were identified as the major requirement for special purpose equipment

  10. Proceedings of FED remote maintenance equipment workshop

    Energy Technology Data Exchange (ETDEWEB)

    Sager, P.; Garin, J.; Hager, E.R.; Spampinato, P.T.; Tobias, D.; Young, N.

    1981-11-01

    A workshop was convened in two sessions in January and March 1981, on the remote maintenance equipment for the Fusion Engineering Device (FED). The objectives of the first session were to familiarize the participants with the status of the design of the FED and to develop a remote maintenance equipment list for the FED. The objective of the second session was to have the participants present design concepts for the equipment which had been identified in the first session. The equipment list was developed for general purpose and special purpose equipment. The general purpose equipment was categorized as manipulators and other, while the special purpose equipment was subdivided according to the reactor subsystem it serviced: electrical, magnetic, and nuclear. Both mobile and fixed base manipulators were identified. Handling machines were identified as the major requirement for special purpose equipment.

  11. Aircraft Wiring Support Equipment Integration Laboratory (AWSEIL)

    Data.gov (United States)

    Federal Laboratory Consortium — Purpose: The Aircraft Wiring Support Equipment Integration Laboratory (AWSEIL) provides a variety of research, design engineering and prototype fabrication services...

  12. 装备采购仿真系统总体设计研究%Research on Overall Design of Equipment Acquisition Simulation System

    Institute of Scientific and Technical Information of China (English)

    王健

    2015-01-01

    针对我军装备采购仿真系统建设过程中总体规划不足,技术标准不清的现实问题,按照软件工程化管理的逻辑思维,在全面分析系统建设需求的基础上,提出系统基本功能布局和总体设计方案;明确了系统在需求分析、立项论证和研制3个主要采购阶段的功能定位;提出了基于 HLA 基本思想的4层体系结构,支持系统实现仿真环境下的需求论证与评估、技术成熟度评估和项目核心要素管理等主要装备采购活动。%Aiming at existing problems during construction of our military equipment acquisition simulation such as inadequate overall planning and unclear technical standards,according to the logics of software engineering management,based on requirements analysis of system construction,the pa‐per puts forward basic functional layout and general design scheme of the system,make clear func‐tional layout of system in three main acquisition phases:requirement analysis,project demonstration and development and puts forward a HLA‐based four‐layer architectural structure to support main e‐quipment acquisition activities including demonstration and evaluation of system requirements,evalu‐ation on technology maturity and core elements management of project in a simulation environment.

  13. 太阳能温室装备化的构想与新设计%The idea of solar greenhouse equipment and new design

    Institute of Scientific and Technical Information of China (English)

    文麒麟; 石能文; 郑宏飞; 文鹏

    2012-01-01

      温室是解决农产品跨季节生长和地域性紧缺的有效途径,在温室中配置太阳能集热和储能单元构成储能型太阳能温室可以改善作物的微气候,同时可以保证作物在高寒地区寒冷季节正常生长。文章系统综述了储能型太阳能温室技术的发展,介绍了近几年温室技术与太阳能技术的结合情况,分析储能型太阳能温室技术的发展趋势,提出储能型太阳能温室装备化的构想,给出了一个新设计结构,为太阳能在农业生产上的利用提供借鉴。%  The greenhouse is an effective way to solve inter-seasonal growth of agricultural products and regional shortage. Configuration of solar collectors and energy storage unit storage-type solar greenhouse can improve the microclimate of the crop in the greenhouse, at the same time, can guarantee the normal growth of crops in the cold season and the cold region. In the article,development of storage type solar greenhouse technology was systematically summarized, the combination of the recent years' greenhouse technology and solar energy technology were introduced, the development trend of energy storage type solar greenhouse technology was analyzed, the idea of the equipment of energy storage type solar greenhouse was put forward, and a new design structure was gave, so reference was provided for agricultural production use.

  14. 铝合金桁架环缝自动焊机的研制%Design and manufacture of automatic circumferential welding equipment for aluminium alloy boom

    Institute of Scientific and Technical Information of China (English)

    田松亚; 封艳

    2012-01-01

    根据铝合金桁架铝合金管材与接头环缝焊接要求,设计并制造了一台专用焊接设备.根据焊接时序要求,采用可编程控制器实现对焊接设备逻辑顺序的控制,并制定了铝合金桁架铝合金管材与接头环缝的惰性气体保护焊MIG自动焊接工艺.结果表明,该焊机自动化程度高、性能稳定、操作简便,能够满足铝桁架铝合金管材与接头环缝自动焊生产要求,同时提高了生产率.依据制定的焊接工艺,进行了焊接试验.焊接试验表明,制定的工艺所获得的铝合金桁架铝合全管材与接头对接接头,满足焊缝质量要求.%According to the requirements of aluminium alloy boom circumferential welding,this paper design and manufacture a special automatic welding equipment.In terms of weld time sequence requirement,PLC is used to implement the control of welding device logical subsequence.besides.work out the MIG automatic welding procedure of circumferential welding.The Result shows that the welding device displays high degree of automation,stable performance and convenient movement,which could satisfy production requirements of aluminium alloy boom automatic circumferential welding and improve productivity .Based on the welding procedure, welding experiment is done.The result indicates that welding procedure could reach the quality requirements of welding joint.

  15. 无缝钢管水淬火设备的水系统设计及应用%Design and Application of Water System for Water-Quenching Equipment in Seamless Steel Pipes

    Institute of Scientific and Technical Information of China (English)

    曹金娣; 张平; 赵会

    2014-01-01

    The composition and layout of the water system of seamless steel tube water quenching equip-ment are introduced,the calcualtion and theoretical basis of the part in design are discussed,which can provide reference for practical application.%介绍无缝钢管水淬火设备的水系统组成及布置,简述该部分在研发设计中的计算及理论依据,可为实际应用提供参考。

  16. Formation of simple biomolecules from alanine in ocean by impacts

    Science.gov (United States)

    Umeda, Y.; Sekine, T.; Furukawa, Y.; Kakegawa, T.; Kobayashi, T.

    2013-12-01

    The biomolecules on the Earth are thought either to have originated from the extraterrestrial parts carried with flying meteorites or to have been formed from the inorganic materials on the Earth through given energy. From the standpoint to address the importance of impact energy, it is required to simulate experimentally the chemical reactions during impacts, because violent impacts may have occurred 3.8-4.0 Gyr ago to create biomolecules initially. It has been demonstrated that shock reactions among ocean (H2O), atmospheric nitrogen, and meteoritic constitution (Fe) can induce locally reduction environment to form simple bioorganic molecules such as ammonia and amino acid (Nakazawa et al., 2005; Furukawa et al., 2009). We need to know possible processes for alanine how chemical reactions proceed during repeated impacts and how complicated biomolecules are formed. Alanine can be formed from glycine (Umeda et al., in preparation). In this study, we carried out shock recovery experiments at pressures of 4.4-5.7 GPa to investigate the chemical reactions of alanine. Experiments were carried out with a propellant gun. Stainless steel containers (30 mm in diameter, 30 mm long) with 13C-labeled alanine aqueous solution immersed in olivine or hematite powders were used as targets. Air gap was present in the sample room (18 mm in diameter, 2 mm thick) behind the sample. The powder, solution, and air represent meteorite, ocean, and atmosphere on early Earth, respectively. Two powders of olivine and hematite help to keep the oxygen fugacity low and high during experiments, respectively in order to investigate the effect of oxygen fugacity on chemical processes of alanine. The recovered containers, after cleaned completely, were immersed into liquid nitrogen to freeze sample solution and then we drilled on the impact surface to extract water-soluble run products using pure water. Thus obtained products were analyzed by LC/MS for four amino acids (glycine, alanine, valine, and

  17. Containment and Surveillance Equipment Compendium

    International Nuclear Information System (INIS)

    The Containment and Surveillance Equipment Compendium contains information sections describing the application and status of seals, optical surveillance systems, and monitors for international safeguards systems. The Compendium is a collection of information on equipment in use (generally by the IAEA) or under development in the US in diverse programs being conducted at numerous facilities under different sponsors. The Compendium establishes a baseline for the status and applications of C/S equipment and is a tool to assist in the planning of future C/S hardware development activities. The Appendix contains design concepts which can be developed to meet future goals

  18. Equipment for ion beam production

    International Nuclear Information System (INIS)

    An equipment has been designed to extend the scope of control of ion beam flux for an intensive ion beam source used for plasma injection in magnetic vessels. The control equipment is connected to the electromagnet power supply. A consumption regulator is fitted in the operating gas supply to the hollow cathode of the ion source. A circuit is also included for discharge voltage maintenance consisting of a control element and a discharge voltage pick-up. (M.D.). 1 fig

  19. 123I and 13I purification for biomolecules labelling

    International Nuclear Information System (INIS)

    The 123I and 131I are iodine radioisotopes widely used in Nuclear Medicine. The radioisotope 123I is used in diagnosis through the SPECT technique and is routinely produced at IPEN in cyclotron through the reaction: '124Xe (p, 2n) '123Cs -> 123Xe -> 123I. The radioisotope 131I is used both in diagnosis and therapy due to its physical characteristics of decay by β- and its γ-ray emissions that are softened with the use of specific collimators for diagnosis. It is routinely produced at IPEN using the nuclear reactor through the indirect reaction: 130Te (n, γ) ->131Te -> 131I, irradiating compounds containing Te. The radiopharmaceuticals prepared with these radioisotopes go through rigorous quality control tests and the chemical purity of the primary radioisotopes 123I and 131I are within the permissible limits currently defined. However, the presence of some chemical contaminants can prejudice the biomolecules labeling (monoclonal antibodies and peptides), that will produce radiopharmaceuticals of first generation to the oncology area. The aim of this work was to obtain a new purification method of these radioisotopes, allowing the labeling of biomolecules and also to established a process control on those radioisotopes. The methodology was separated on 3 steps: Evaluation of '123I e 131I radionuclidic purity using a hyper pure germanium detector, chemical purity using ICP-OES and the retention and elution study of 131I in several absorbers to choose the most appropriate for the purification tests analyzing the behavior of the possible contaminants. The radionuclidic analyses showed the presence of Te and Co on 131I samples and Te, Tc e Co on 123I samples. The chemical purity analyses showed the presence of Al and Mo in 123I, coming from the window material of the target holder and the presence of Al and Te in 131I samples, coming from the target holder and the target, respectively. The retention and elution study selected the most promising adsorber to the

  20. Cold atmospheric plasma sterilization: from bacteria to biomolecules

    Science.gov (United States)

    Kong, Michael

    2009-10-01

    Although ionized gases have been known to have biological effects for more than 100 years, their impact on the practice in healthcare service became very significant only recently. Today, plasma-based surgical tools are used for tissue reduction and blood coagulation as surgical procedures. Most significant however is the speed at which low-temperature gas plasmas are finding new applications in medicine and biology, including plasma sterilization, wound healing, and cancer therapies just to name a few. In the terminology of biotechnology, the ``pipeline'' is long and exciting. This presentation reviews the current status of the field with a particular emphasis on plasma inactivation of microorganisms and biomolecules, for which comprehensive scientific evidence has been obtained. Some of the early speculations of biocidal plasma species are now being confirmed through a combination of optical emission spectroscopy, laser-induced fluorescence, mass spectrometry, fluid simulation and biological sensing with mutated bacteria. Similarly, fundamental studies are being performed to examine cell components targeted by gas plasmas, from membrane, through lipid and membrane proteins, to DNA. Scientific challenge is significant, as the usual complexity of plasma dynamics and plasma chemistry is compounded by the added complication that cells are live and constantly evolving. Nevertheless, the current understanding of plasma inactivation currently provides strong momentum for plasma decontamination technologies to be realized in healthcare. We will discuss the issue of protein and tissue contaminations of surgical instruments and how cold atmospheric plasmas may be used to degrade and reduce their surface load. In the context of plasma interaction with biomolecules, we will consider recent data of plasma degradation of adhesion proteins of melanoma cells. These adhesion proteins are important for cancer cell migration and spread. If low-temperature plasmas could be used to

  1. Si Nanopores Development for External Control of Transport of Biomolecules

    Energy Technology Data Exchange (ETDEWEB)

    Ileri, N; Tringe, J; Letant, S; Palozoglu, A; Stroeve, P; Faller, R

    2008-06-13

    Nazar Ileri has been involved in an independent, multidisciplinary effort to create a new class of molecular sieves for proteins and viruses. Her experimental work has been performed concurrently at two campuses, LLNL and UC Davis, while theoretical components have been largely accomplished at UC Davis. As will be described, the devices she is creating have great potential to improve very significantly the efficiency and selectivity of molecular transport over what is presently available from state-of-the-art membranes. Our biotechnology training program is based on an integrated study of the transport of biomolecules through conically-shaped, nanoporous silicon membranes. The overall objective of this effort is to demonstrate an efficient, highly selective membrane technology that is manufacturable for macroscopic areas and can be employed in sensing, diagnostic and biomedical applications. Our specific aims are to (1) fabricate and characterize the physical characteristics of the membranes, (2) to demonstrate their utility for molecular transport and separation, and (3) to develop models that will facilitate understanding of these devices as well as improved performance of the next generation of devices. We have proposed that the conical pores have superior performance characteristics compared to other porous filters. To study this hypothesis, complementary approaches from different disciplines, such as membrane synthesis, experiment, and molecular simulation need to be combined. This provides an ideal training environment for a future leader in biotechnology. Hence, for this study, Nazar Ileri has started to carry out a full range of experimental and theoretical investigations under our guidance. First, she has begun fabrication of filters with conical/pyramidal pores. She characterized the pores by AFM and SEM, and analyzed the images using wavelets and other mathematical tools. She has also started to conduct biomolecule transport experiments to compare the

  2. Design and Realization of Leasing Management System of Medical Equipment in Hospital%医疗设备租赁管理系统的设计与实现

    Institute of Scientific and Technical Information of China (English)

    黄志伟; 邹蓉博

    2011-01-01

    Based on the requirement of Device Department in hospital, we designed a leasing management system of the medical equipment in hospital. The system not only improved the equipment' s utility rate, reduced the cost, but also understood the use of instruments, provided reliable and stable medical equipment for clinical.%本文根据医院设备科的实际需求,设计开发了一套医院内部医疗设备租赁管理系统.该系统的应用不仅提高了医疗仪器的使用率,降低了成本,更重要的是能够及时提供全院仪器的租赁使用情况,为临床科室提供可靠、稳定的医疗设备相关信息.

  3. 火炮驻退杆变深度沟槽测量专机设计与应用%Design and applications of the special detection equipment for variable depth groove in cannon recoil rod

    Institute of Scientific and Technical Information of China (English)

    谭胜龙; 龚运环

    2012-01-01

    针对火炮驻退杆变深度沟槽加工后人工手动检测精度低,效率低,影响火炮生产线生产效率的问题,结合某火炮驻退杆生产线设备火炮驻退杆拉槽机,设计了用于驻退杆变深度沟槽测量专机,实现自动化测量.%Aiming at the low precision and low efficiency of the manual measurement for the variable depth of groove in the cannon recoil rod, and considering the manual measurement affecting the cannon production efficiency. To link up with the equipments of cannon recoil rod production line, a special detection equipment for variable depth groove in cannon recoil rod is designed, and this equipment runs automatically.

  4. 基于RFID的电力通信设备管理系统的设计与应用%Design and Application of Management System of Power Communication Equipment Based on RFID Technology

    Institute of Scientific and Technical Information of China (English)

    王阳; 张正文

    2013-01-01

      针对目前电力通信设备仓库管理中存在的问题,设计应用基于RFID的B/S模式通信设备管理系统,实现对电力通信设备的动态管理,节约人力和物资成本,提高精益集约化管理水平。%Power communications equipment for the current problems in warehouse management was discussed. Designing RFID-based applications B/S mode communication device management system, automatically collect information communication equipment, to achieve the dynamic management of power communication equipment, saving manpower and material costs, increase lean intensive management level.

  5. Laser-guided direct writing: a novel method to deposit biomolecules for biosensors arrays.

    Science.gov (United States)

    Xu, Juntao; Grant, Sheila A; Pastel, Robert L

    2003-01-01

    In this paper, we present a potential biomolecular patterning method, laser-guided direct writing guidance (LGDW), which may be utilized to deposit organic and bioactive particles for biosensor arrays. The instrumentation and operation of the LGDW system is introduced and the system settings used to achieve deposition are reported. The biomolecule, avidin, was deposited onto a substrate using LGDW to evaluate the possible damage from the laser on the biomolecules. The functionality of avidin after laser-based guidance was examined by exposing the deposited avidin molecules to its ligand, biotin. The results show some avidin retained its affinity to biotin after LGDW demonstrating little damage to the biomolecules.

  6. Personal protective equipment

    International Nuclear Information System (INIS)

    This Practical Radiation Technical Manual is one of a series that has been designed to provide guidance on radiological protection for employers, radiation protection officers, managers and other technically competent persons who have responsibility for ensuring the safety of employees working with ionizing radiation. The Manual may be used with the appropriate IAEA Practical Radiation Safety Manuals to provide training, instruction and information for all employees engaged in work with ionizing radiation. Personal protective equipment (PPE) includes clothing or other special equipment that is issued to individual workers to provide protection against actual or potential exposure to ionizing radiations. It is used to protect each worker against the prevailing risk of external or internal exposure in circumstances in which it is not reasonably practicable to provide complete protection by means of engineering controls or administrative methods. Adequate personal protection depends on PPE being correctly selected, fitted and maintained. Appropriate training for the users and arrangements to monitor usage are also necessary to ensure that PPE provides the intended degree of protection effectively. This Manual explains the principal types of PPE, including protective clothing and respiratory protective equipment (RPE). Examples of working procedures are also described to indicate how PPE should be used within a safe system of work. The Manual will be of most benefit if it forms part of a more comprehensive training programme or is supplemented by the advice of a qualified expert in radiation protection. Some of the RPE described in this Manual should be used under the guidance of a qualified expert

  7. Equipment for gas conversion

    Energy Technology Data Exchange (ETDEWEB)

    Tabata, K.; Matsumoto, I.

    1983-01-28

    Equipment is proposed for vapor conversion of hydrocarbons (Uv), possibly in a mixture with air, in order to produce an inorganic gas, which chiefly consists of H2 and COx. It consists of a reaction pipe made of an inorganic refractory ceramic and equipped along the wall circumference with heaters. The reaction pipe is filled with a combined, multilayer catalyst (Kt) carrier, made of gamma-A1203 which in the transverse cross section has a multipore reticular or fibrous structure. Replacement of the traditional steel (St) materials for the walls of the reaction pipe with ceramic materials reduces the output of the hydrocarbon which contaminates the surface (Pv) of the catalyst; the use of a multilayer carrier for the catalyst made of gamma-A1203 with a porous reticular or fibrous structure reduces the pressure losses in the reactor and facilitates the replacement of the spent catalyst. The equipment is designed for vapor conversion of natural gas, C3H8, and vapors of kerosene, naphtha and so on.

  8. Direct ultimate disposal of spent fuel. Simulation of shaft transport. Proof of state-of-the-art of a conceptual design of a shaft hoisting equipment for a max. payload of 85 t (TA 2)

    International Nuclear Information System (INIS)

    The reported conceptual design is the first of its kind worldwide for design payloads of this dimension, intended for the POLLUX containers. In order to prove the feasibility and thus the licensibility of the hoisting engineering concept, the first project task was to establish the design of the shaft hoisting equipment. The design of the essential components and sub-systems is based on the requirements of the existing safety guides and engineering codes determining the design quantities to be selected. According to a specific catalogue of criteria developed for this purpose, nine existing German hoisting facilities were selected as reference systems. The criteria are: establishment of a database allowing verification, site variance, payloads and rope loads, rope diameters, design type, number of ropes, performance conditions. The report explains the structural members, components and processes that could be tested and verified by existing reference facilities, and those which remained to be designed and verified in the completely new approach. (orig./HP)

  9. Microfluidic Droplet Dehydration for Concentrating Processes in Biomolecules

    Science.gov (United States)

    Anna, Shelley

    2014-03-01

    Droplets in microfluidic devices have proven useful as picoliter reactors for biochemical processing operations such as polymerase chain reaction, protein crystallization, and the study of enzyme kinetics. Although droplets are typically considered to be self-contained, constant volume reactors, there can be significant transport between the dispersed and continuous phases depending on solubility and other factors. In the present talk, we show that water droplets trapped within a microfluidic device for tens of hours slowly dehydrate, concentrating the contents encapsulated within. We use this slow dehydration along with control of the initial droplet composition to influence gellation, crystallization, and phase separation processes. By examining these concentrating processes in many trapped drops at once we gain insight into the stochastic nature of the events. In one example, we show that dehydration rate impacts the probability of forming a specific crystal habit in a crystallizing amino acid. In another example, we phase separate a common aqueous two-phase system within droplets and use the ensuing two phases to separate DNA from an initial mixture. We further influence wetting conditions between the two aqueous polymer phases and the continuous oil, promoting complete de-wetting and physical separation of the polymer phases. Thus, controlled dehydration of droplets allows for concentration, separation, and purification of important biomolecules on a chip.

  10. Small biomolecule immunosensing with plasmonic optical fiber grating sensor.

    Science.gov (United States)

    Ribaut, Clotilde; Voisin, Valérie; Malachovská, Viera; Dubois, Valentin; Mégret, Patrice; Wattiez, Ruddy; Caucheteur, Christophe

    2016-03-15

    This study reports on the development of a surface plasmon resonance (SPR) optical fiber biosensor based on tilted fiber Bragg grating technology for direct detection of small biomarkers of interest for lung cancer diagnosis. Since SPR principle relies on the refractive index modifications to sensitively detect mass changes at the gold coated surface, we have proposed here a comparative study in relation to the target size. Two cytokeratin 7 (CK7) samples with a molecular weight ranging from 78 kDa to 2.6 kDa, respectively CK7 full protein and CK7 peptide, have been used for label-free monitoring. This work has first consisted in the elaboration and the characterization of a robust and reproducible bioreceptor, based on antibody/antigen cross-linking. Immobilized antibodies were then utilized as binding agents to investigate the sensitivity of the biosensor towards the two CK7 antigens. Results have highlighted a very good sensitivity of the biosensor response for both samples diluted in phosphate buffer with a higher limit of detection for the larger CK7 full protein. The most groundbreaking nature of this study relies on the detection of small biomolecule CK7 peptides in buffer and in the presence of complex media such as serum, achieving a limit of detection of 0.4 nM. PMID:26432194

  11. Hybrid carbon nanomaterials for electrochemical detection of biomolecules

    Science.gov (United States)

    Laurila, Tomi

    2015-09-01

    Electrochemical detection of different biomolecules in vivo is a promising path towards in situ monitoring of human body and its functions. However, there are several major obstacles, such as sensitivity, selectivity and biocompatiblity, which must be tackled in order to achieve reliably and safely operating sensor devices. Here we show that by utilizing hybrid carbon materials as electrodes to detect two types of neurotransmitters, dopamine and glutamate, several advantages over commonly used electrode materials can be achieved. In particular, we will demonstrate here that it is possible to combine the properties of different carbon allotropes to obtain hybrid materials with greatly improved electrochemical performance. Three following examples of the approach are given: (i) diamond-like carbon (DLC) thin film electrodes with different layer thicknesses, (ii) multi-walled carbon nanotubes grown directly on top of DLC and (iii) carbon nanofibres synthesized on top of DLC thin films. Detailed structural and electrochemical characterization is carried out to rationalize the reasons behind the observed behvior. In addition, results from the atomistic simulations are utilized to obtain more information about the properties of the amorphous carbon thin films.

  12. Radiation damage of biomolecules (RADAM) database development: current status

    International Nuclear Information System (INIS)

    Ion beam therapy offers the possibility of excellent dose localization for treatment of malignant tumours, minimizing radiation damage in normal tissue, while maximizing cell killing within the tumour. However, as the underlying dependent physical, chemical and biological processes are too complex to treat them on a purely analytical level, most of our current and future understanding will rely on computer simulations, based on mathematical equations, algorithms and last, but not least, on the available atomic and molecular data. The viability of the simulated output and the success of any computer simulation will be determined by these data, which are treated as the input variables in each computer simulation performed. The radiation research community lacks a complete database for the cross sections of all the different processes involved in ion beam induced damage: ionization and excitation cross sections for ions with liquid water and biological molecules, all the possible electron – medium interactions, dielectric response data, electron attachment to biomolecules etc. In this paper we discuss current progress in the creation of such a database, outline the roadmap of the project and review plans for the exploitation of such a database in future simulations.

  13. Quantification of specific bindings of biomolecules by magnetorelaxometry

    Directory of Open Access Journals (Sweden)

    Steinhoff Uwe

    2008-03-01

    Full Text Available Abstract The binding reaction of the biomolecules streptavidin and anti-biotin antibody, both labelled by magnetic nanoparticles (MNP, to biotin coated on agarose beads, was quantified by magnetorelaxometry (MRX. Highly sensitive SQUID-based MRX revealed the immobilization of the MNP caused by the biotin-streptavidin coupling. We found that about 85% of streptavidin-functionalised MNP bound specifically to biotin-agarose beads. On the other hand only 20% of antibiotin-antibody functionalised MNP were specifically bound. Variation of the suspension medium revealed in comparison to phosphate buffer with 0.1% bovine serum albumin a slight change of the binding behaviour in human serum, probably due to the presence of functioning (non heated serum proteins. Furthermore, in human serum an additional non-specific binding occurs, being independent from the serum protein functionality. The presented homogeneous bead based assay is applicable in simple, uncoated vials and it enables the assessment of the binding kinetics in a volume without liquid flow. The estimated association rate constant for the MNP-labelled streptavidin is by about two orders of magnitude smaller than the value reported for free streptavidin. This is probably due to the relatively large size of the magnetic markers which reduces the diffusion of streptavidin. Furthermore, long time non-exponential kinetics were observed and interpreted as agglutination of the agarose beads.

  14. Study of Integrated Equipment Support System Design Based on Data Warehouse%基于数据仓库的装备综合保障系统设计研究

    Institute of Scientific and Technical Information of China (English)

    代冬升; 谢峰; 孙江生; 梁伟杰

    2014-01-01

    目的:使各类装备保障信息系统中的装备保障数据得到综合利用,实现服务上级决策支持的功能。方法提出设计综合性的装备保障系统的构想,阐述构建装备保障数据仓库的总体方式,并针对体系结构、运行流程、中心数据库结构、运维管理等方面进行设计。结果形成了融入知识库等多数据库的扩展数据仓库,从理论的角度对构建装备数据仓库以支持。结论装备综合保障系统的设计思想与设计理论,为系统的最终实现奠定了理论基础,为推动装备保障信息化发展起到重要作用。%Objective To achieve comprehensive utilization of the equipment support data in various equipment support information systems, and realize the function of supporting leadership decisions. Methods The design of an integrated e-quipment support system was proposed. The overall approach of building equipment data warehouse was expounded and the architecture, running processes, structure of center database as well as running management were designed in this article. Results An expended data warehouse integrating multiple databases including knowledge database was formed, and the con-struction of equipment warehouse was supported from the theoretical point of view. Conclusion The design ideas and design theory of an integrated equipment support system laid a theoretical foundation for the final realization of the system, and is of great importance for promoting the development of equipment support information technology.

  15. Conductive Paper with Antibody-Like Film for Electrical Readings of Biomolecules

    Science.gov (United States)

    Tavares, Ana P. M.; Ferreira, Nádia S.; Truta, Liliana A. A. N. A.; Sales, M. Goreti F.

    2016-05-01

    This work reports a novel way of producing an inexpensive substrate support to assemble a sensing film, designed for the electrical transduction of an intended biomolecule. The support uses cellulose paper as substrate, made hydrophobic with solid wax and covered by a home-made conductive ink having graphite as core material. The hydrophobicity of the paper was confirmed by contact angle measurements and the conductive ink composition was optimized with regard to its adhesion, conductivity, and thermal stability. This support was further modified targeting its application in quantitative analysis. Carnitine (CRT) was selected as target compound, a cancer biomarker. The recognition material consisted of an antibody-like receptor film for CRT, tailored on the support and prepared by electrically-sustained polymerization of 3,4-ethylenedioxythiophene (EDOT) or dodecylbenzenesulfonic acid (DBS). Fourier transform infrared spectroscopy (FTIR) and Raman spectroscopy analysis confirmed the presence of the polymeric film on the support, and the performance of the devices was extensively evaluated with regard to linear response ranges, selectivity, applicability, and reusability. Overall, the paper-based sensors offer simplicity of fabrication, low cost and excellent reusability features. The design could also be extended to other applications in electrical-based approaches to be used in point-of-care (POC).

  16. 一种机载设备的中央处理单元模块的设计与实现%Design and Implementation of a Central Process Unit in Airborne Equipment

    Institute of Scientific and Technical Information of China (English)

    王俊; 吕俊; 杨宁

    2014-01-01

    The design and implementation of a central process unit in airborne equipment is introduced in this paper. The airborne equipment receives instruction signals from flight control system via RS422 communication, then the central process unit implements controlling, data calculation, A/D conversion, and feedback the result to actuuating mechanism, so that implementing the expected functions of airborne equipment. The equipment has been used in the airborne which proves that this design is referential and practical.%文章介绍了一种机载设备的中央处理单元模块设计与实现。机载设备通过RS422通讯接收飞行控制系统发来的指令信号,中央处理单元完成控制、数据解算、A/D转换等功能,将结果反馈给执行机构,从而实现机载设备的预期功能。本设备已在飞机上使用,使用结果良好,因此具有较强的参考性和实用性。

  17. Design Points for the Equipment and Piping Arrangement of Flammable Liquid Tank Farm%可燃液体罐区设备及管道布置设计要点

    Institute of Scientific and Technical Information of China (English)

    张慧

    2015-01-01

    可燃液体罐区是化工装置不可或缺的重要设施,其设备选型、管道布置等在设计上是有较高要求的,正确的设备及管道布置对罐区起着至关重要的安全保障作用。本文以甲醇为例,介绍了可燃液体储罐的设计选型、容量确定、设备布置及与之相通管道的设计要点,可为今后的可燃液体储罐的相关设计提供参考与借鉴。%Flammable liquid tank farm is an indispensable facility in chemical devices. Equipment selection, piping arrangement etc. have to meet higher requirements. Correct equipment and piping arrangement play an important guarantee role in the safety of the farm. In this paper, the methanol plant was introduced as an example for the design of unit mode selection, capacity determination, equipment arrangement and piping arrangement. This will offer some references for the design of the equipment and piping arrangement in the flammable liquid tank farm.

  18. Monitoring Framework Design for Logistics Equipment Based on RFID%基于RFID的物流装备信息监控网络平台设计

    Institute of Scientific and Technical Information of China (English)

    刘富春; 周受钦

    2012-01-01

    Containers are the core equipment of the logistics transportation in the world,and over 90 percent of the international transportation is accomplished by containers. The effectiveness of logistics and custom clearance it due to the lag in technology of intelligence and informationization of the container transportation,and unable to monitor in visualized mode. It investigates the developments of the monitoring and management of the smart containers based on the RFID technique,and designs the system platform for internet of things based on the smart containers. This platform can make the overall supply chain information unopposed, and can enhance the effectiveness of the modern logistics. This research provides the perfect product and technique scheme for smart container applications.%集装箱是全球物流运输的核心装备,全球国际货运90%以上都是通过集装箱完成,目前集装箱运输的智能化和信息化技术落后,从而导致物流效率低、海关通关效率低且做不到实时可视化监控.文中基于射频识别和嵌入式徽控制器技术开发了用于托盘和集装箱等物流装备的智能数据采集终端,进而设计了基于智能集装箱的现代物流装备物联网系统平台.该平台的广泛应用使现代物流系统的整个供应链信息流畅通,实现了可视化监控,大幅度提高了现代物流效率.为行业应用提供智能集装箱成熟产品和技术方案.

  19. Design and Simulation of a Var Compensation Equipment%一种无功补偿装置设计与仿真

    Institute of Scientific and Technical Information of China (English)

    闫国琦; 庞树杰; 李继宇

    2012-01-01

    By establishing a non-inductive load filter capacitor current AC-DC switching circuit, the output lags the system voltage by 1/4 cycle of SPWM frequency control method and system to make inductive load energy exchange occurs, to replace the capacitor compensation system inductance inductive successful results. And through the Y/A three-phase transformer connected with the work of the single-phase compensation circuit, eliminating the larger single-phase compensation circuit of 3 harmonics, make compensation circuit excluding low-order harmonic. Based on this principle, a kind of reactive power compensation in power system of power capacitor using inductively instead of control method was proposed, and studies the reactive power compensation device parameters design. To reactive power compensator capacity and voltage, by reducing the impact of the current power capacitor, improving the working reliability and reduce the cost of equipment. Using the circuit simulation software, the compensation effect was tested, and the compensation method was demonstrated.%通过建立一个不含滤波电容的电感负载交直交换流电路,利用输出滞后系统电压1/4工频周期的SPWM控制方法,使电感负载与系统感性负载发生能量交换,达到电感代替电容补偿系统感性无功的效果.并通过Y/△三相变压器连接3个配合工作的单相补偿电路,消去单相补偿电路中较大的3次谐波,使三相补偿电路不含低次谐波.基于该原理,提出一种在电力系统无功补偿中利用电感代替功率电容的控制方法,并研究该无功补偿装置的参数设计.有利于无功补偿器容量和电压的提升,减少由功率电容带来的冲击电流,提高了工作可靠性和降低了设备成本.用仿真软件建立算例电路检验补偿效果,并论证了补偿方法.

  20. The increased safety level for structures, equipment and pipe networks by use of shock, vibration and seismic damping mechanical devices as per SERB -CITON design

    International Nuclear Information System (INIS)

    Full text: The paper presents a solution for diminishing the shocks, vibrations and seismic movements in pipe networks, simultaneously with the reduction of the general stress conditions in piping and supports. The total removal or reduction of vibrations is a hard problem which is not yet managed neither theoretically, through analyses of the occurrence and development of shocks and vibrations in complex systems, nor by experimental studies, because the current supports and dampers cannot provide enough damping within all the frequency ranges met in the current technical domain. Often, the stiffness of classic supports do not allow a satisfactory isolation of the shock and vibration sources as to eliminate their propagation in the environment and to protect the pipe networks and equipment against the shocks and vibrations coming from the surrounding environment. Considering the actual condition met in the nuclear power plants, power plants and thermal power plants, etc this paper represents a major practical aid because it provides new solutions for diminishing the effects of shocks, vibrations and seismic movements. This paper presents the results of the works aiming at diminishing the effects of vibrations in pipe networks, obtained in the design, construction and testing of new types of supports. These include sandwich type components made up of elastic blade packages with controlled distortion provided by the central and peripheral stiff parts called SERB - PIP. With the new type of supports, the control of the distortion at static and dynamic testing and the thermal displacements is achieved by the relative movement between the sandwich structure subassemblies and by the sandwich structure distortion controlled by the central and peripheral distorting parts that generate a non - linear geometric response. These have an easily controllable stiffness and damping, due to their non - linear geometric behaviour. The new type of supports are adjustable to the load

  1. 大型在线设备管理中自动图表的设计%Design for Automatic Plot of Large On-line Equipment Management

    Institute of Scientific and Technical Information of China (English)

    郭锐

    2016-01-01

    大型在线设备通常工作在生产线或重要的流水线上,因此在实际的工作过程中对设备各部件的工作时间的要求非常严格,在设备的设计、生产、测试、监控和维护过程中都需要对设备的工作时间进行管理,传统的方法是通过软件将传感器数据或运行日志直接在Excel中记录时间数据,数据获得方式直接且方便,但是不利于人员理解数据含义。为了提高管理效率,提出了利用VBA技术开发根据数据自动绘制甘特图图表的方法。此法能够大幅提高数据的可读性,并大量减少人工工作量,为多个部门的管理、沟通工作带来极大方便。%Large on-line equipment usually works on a production line or an important pipeline , so the requirement on the working time of each component is very strict in practical working process .The time management is especially important during all processes of de-sign, production, test, monitoring and maintaining .The traditional method of time management is to directly record time data of sensors or logs into Excel sheets by software .This method of obtaining data is direct and convenient , but it goes against the comprehension of the information by the stuff .To improve management efficiency , this paper presents a method of drawing Gantt chart automatically ac-cording to data by using VBA technology , which increases the readability of massive data , reduces workload and brings convenience for management and communication in several departments of a company .

  2. 金属丝杨氏模量测量装置的设计%Design of the Measuring Equipment to Explore Wire Young’ s Modulus

    Institute of Scientific and Technical Information of China (English)

    李儒颂; 叶文江

    2014-01-01

    Based on Michelson interference principle,the measuring equipment to explore wire Young’ s modu-lus is designed. A continuous and uniform increase force applied to wire will induce a small elongation,which makes the moving mirror move by the sensitive lever and causes the change of optical screen interference ring number. The light intensity signal is detected by a photoelectric sensor,and then through the analog to digital conversion the optical signals are converted to electrical signals,in the end the small elongation of wire can be measured after calculating accurately the interference ring number. The external applied force can be directly measured by the force sensor. The software of Origin is used to process the experimental data to avoid the man-made error,and then the wire Young ¢s modulus can be calculated intelligently.%基于迈克尔逊干涉原理设计了金属丝杨氏模量的测量装置。在金属丝上施加持续而又均匀增加的力,引起金属丝细微伸长,通过灵敏杠杆带动移动镜的移动,从而引起光屏上干涉圆环数目的变化;用一种光电传感器捕捉干涉圆环的光强信号,将光信号转换为电信号,再通过模数转换,精确算出干涉圆环的条数,就可以实现对金属丝微小伸长量的测量。采用Origin软件处理实验数据,避免了人为因素所造成的误差,智能化计算出金属丝的杨氏模量。

  3. Synthesis of vaterite and aragonite crystals using biomolecules of tomato and capsicum

    Science.gov (United States)

    Chen, Long; Xu, Wang-Hua; Zhao, Ying-Guo; Kang, Yan; Liu, Shao-Hua; Zhang, Zai-Yong

    2012-12-01

    In this paper, biomimetic synthesis of calcium carbonate (CaCO3) in the presence of biomolecules of two vegetables-tomato and capsicum is investigated. Scanning electron microscopy and X-ray powder diffractometry were used to characterize the CaCO3 obtained. The biomolecules in the extracts of two vegetables are determined by UV-vis or FTIR. The results indicate that a mixture of calcite and vaterite spheres constructed from small particles is produced with the extract of tomato, while aragonite rods or ellipsoids are formed in the presence of extract of capsicum. The possible formation mechanism of the CaCO3 crystals with tomato biomolecules can be interpreted by particle-aggregation based non-classical crystallization laws. The proteins and/or other biomolecules in tomato and capsicum may control the formation of vaterite and aragonite crystals by adsorbing onto facets of them.

  4. Further development of overcast equipment

    Energy Technology Data Exchange (ETDEWEB)

    Dahlitz, G.; Scholze, U.

    1987-04-01

    Spoil overcast technology is outlined in surface mines by excavator, mobile transfer conveyor and boom spreader combinations. The technology is regarded as adequate for small to medium sited mines with either thin, disturbed, split or multiple seams. The TAKRAF manufacturer, GDR, produces a variety of spreaders (series A/sub 2/ Rs) and transfer conveyors (series BRs). Spoil removal capacity ranges up to 18,000 m/sup 3//h. Schemes of general spreader design are provided. Technological advantages compared to overburden conveyor bridges are noted. Specifications including conveyor boom length, spreading height, equipment mobility, equipment positioning for multiple bench mining and other aspects are discussed. New TAKRAF mobile transfer conveyors (BRs 1200 to BRs 1600) are being developed with extended spreading booms for direct spoil overcast and low equipment height (to fit beneath belt conveyor booms of other surface mining equipment). 4 refs.

  5. 29 CFR 1926.95 - Criteria for personal protective equipment.

    Science.gov (United States)

    2010-07-01

    ... sanitation of such equipment. (c) Design. All personal protective equipment shall be of safe design and.... (2) The employer is not required to pay for non-specialty safety-toe protective footwear...

  6. Bio-NCs - the marriage of ultrasmall metal nanoclusters with biomolecules

    Science.gov (United States)

    Goswami, Nirmal; Zheng, Kaiyuan; Xie, Jianping

    2014-10-01

    Ultrasmall metal nanoclusters (NCs) have attracted increasing attention due to their fascinating physicochemical properties. Today, functional metal NCs are finding growing acceptance in biomedical applications. To achieve a better performance in biomedical applications, metal NCs can be interfaced with biomolecules, such as proteins, peptides, and DNA, to form a new class of biomolecule-NC composites (or bio-NCs in short), which typically show synergistic or novel physicochemical and physiological properties. This feature article focuses on the recent studies emerging at the interface of metal NCs and biomolecules, where the interactions could impart unique physicochemical properties to the metal NCs, as well as mutually regulate biological functions of the bio-NCs. In this article, we first provide a broad overview of key concepts and developments in the novel biomolecule-directed synthesis of metal NCs. A special focus is placed on the key roles of biomolecules in metal NC synthesis. In the second part, we describe how the encapsulated metal NCs affect the structure and function of biomolecules. Followed by that, we discuss several unique synergistic effects observed in the bio-NCs, and illustrate them with examples highlighting their potential biomedical applications. Continued interdisciplinary efforts are required to build up in-depth knowledge about the interfacial chemistry and biology of bio-NCs, which could further pave their ways toward biomedical applications.

  7. 基于结构-设备动力相互作用的户内式变电站抗震设计优化%Seismic design optimization of an indoor substation with structure-equipments interaction

    Institute of Scientific and Technical Information of China (English)

    韩文庆; 王亚超; 盖超; 李风雷; 刘昊

    2013-01-01

    A nonlinear dynamic response analysis with structure-equipments interaction of an integrative building in 110 kV Huangtun substation is studied. The results are compared with that of no structure-equipments interaction, which show it is necessary to considering structure-equipments interaction in integrative building of indoor substation. Under rare earthquake, the structure-equipments interaction should be considered, because the seismic responses of structure and equipments with consideration of the interaction are larger than those without consideration of the interaction. In this condition, the traditional equivalent load method will be insecure anymore. In the last,some optimization measures and reasonable suggestions about seismic design of structure and equipments are introduced.%结合黄屯110 kV变电站生产综合楼设计实例,在结构-电气设备复合体系中考虑二者相互动力作用,分析复合体系在大震弹塑性阶段的地震响应,并与不考虑相互作用的计算模型比较分析.分析结果表明,在大震作用下,电气设备参与整个复合体系的动力反应,使主结构的地震响应变大,同时电气设备本身的动力作用也变大,如仍采用传统的等效荷载法设计是偏不安全的,最后给出主结构和电气设备抗震设计的合理建议和优化措施.

  8. Cu(I), Ag(I), Cd(II), and Pb(II) binding to biomolecules studied by perturbed angular correlation of $\\gamma$-rays (PAC) spectroscopy

    CERN Multimedia

    Metal ions display diverse functions in biological systems and are essential components in both protein and nucleic acid structure and function, and in control of biochemical reaction paths and signalling. Similarly, metal ions may be used to control structure and function of synthetic biomolecules, and thus be a tool in the design of molecules with a desired function. In this project we address a variety of questions concerning both the function of metal ions in natural systems, in synthetic biomolecules, and the toxic effect of some metal ions. All projects involve other experimental techniques such as NMR, EXAFS, UV-Vis, fluorescence, and CD spectroscopies providing complementary data, as well as interpretation of the experimental data by quantum mechanical calculations of spectroscopic properties. The isotopes to be employed in the proposal are the following: $^{111m}$Cd, $^{111}$Ag, $^{199}$mHg, $^{204m}$Pb, $^{61}$Cu, $^{68m}$Cu

  9. DESIGN AND IMPROVEMENT OF QUENCHING EQUIPMENT FOR LARGE-DIAMETER SEAMLESS STEEL PIPE%大口径无缝钢管淬火设备的设计与改进

    Institute of Scientific and Technical Information of China (English)

    王允刚; 陈涛; 李萍; 卢明亮

    2012-01-01

    介绍扬州诚德铜管有限公司大口径无缝铜管热处理生产线的淬火设备。该设备在研发设计过程中,采用了国内外先进的“外淋+旋转+内喷+喷雾”的淬火工艺,以满足一些特种钢管淬火要求。通过对该淬火设备的工作原理、淬火工艺、结构特点的分析,说明了该设备改进后与原有淬火设备在机械结构、淬火效果、力学性能等方面的不同。生产实践表明,该新增淬火设备具备提升产品附加值的能力。%Description of the quenching equipment of large-diameter seamless steel pipe heat treatment line in Yangzhou Chengde Steel Pipe Co., Ltd. The equipment in the design process, using the advanced "external showering + pipe rotating + internal spraying + fog spraying" quenching process in order to meet some special steel hardening requirements. By analysis of the quenching equipment working principle, quenching process and structural features to demonstrate that the improved quenching equipment is more advanced than the original type with the mechanical structure, quenching effect and the pipe' s mechanical properties. Production practice shows the new design quenching equipment have the ability to enhance the value-added products.

  10. The Hardware Design of the Measuring Apparatus of the Hydraulic Flattened System for Certain Armament Equipment%某型装备液压调平系统测试设备的硬件设计

    Institute of Scientific and Technical Information of China (English)

    马久河; 何循来; 陈东根

    2011-01-01

    The basic components of the measuring apparatus of the hydraulic flattened system for certain armament equipment were introduced. The basic principle of its hardware design was carried out. The emphasis was on introduction to the realization of the hardware design, including sensors' setting tool design, main-machine hardware design as well as hardware electromagnetism compati-bEity design.%介绍某型装备液压调平系统测试设备的基本组成,拟定其硬件设计的基本原则,重点介绍硬件设计的实现,包括传感器工装设计、主机硬件设计以及硬件电磁兼容性设计。

  11. Study, design and integration of an FPGA-based system for the time-of-flight calculation applied to PET equipment

    Science.gov (United States)

    Aguilar Talens, D. Albert

    Nuclear Medicine has undergone significant advances in recent years due to improvements in materials, electronics, software techniques, processing etc., which has allowed to considerably extend its application. One technique that has progressed in this area has been the Positron Emission Tomography (PET) based on a non-invasive method with its especial relevance in the evaluation of cancer diagnosis and assessment, among others. This system is based on the principle of data collection and processing from which images of the spatial and temporal distribution of the metabolic processes that are generated inside the body are obtained. The imaging system consists of a set of detectors, normally placed in a ring geometry, so that each one provides information about events that have occurred inside. One of the reasons that have significantly evolved in PET systems is the development of techniques to determine the Time-of-Flight (TOF) of the photons that are generated due to the annihilation of positrons with their antiparticle, the electron. Determining TOF allows one for a more precise location of the events that are generated inside the ring and, therefore, facilitates the task of image reconstruction that ultimately use the medical equipment for the diagnosis and/or treatment. This Thesis begins with the assumption of developing a system based on Field Programmable Gate Arrays (FPGAs) for the integration of a Time- to-Digital Converter (TDC) in order to precisely carry out time measurements. This would permit the estimation of the TOF of the gamma particles for subsequent application in PET systems. First of all, the environment for the application is introduced, justifying the need of the purposed system. Following, the basic principles of PET and the state-of-the-art of similar systems are introduced. Then, the principles of Time-of-Flight based on FPGAs are discussed, and the adopted scheme explained, going into detail in each of its parts. After the development

  12. Design of Discharge Equipments Floor of Ash Silo%灰库卸料设备层的工艺设计

    Institute of Scientific and Technical Information of China (English)

    刘旭

    2012-01-01

    To solve the problem of layout for discharge equipments on the ash silo discharging layer in power plants, according to the basic principles of device arranged on the discharging layer, a kind of new discharge equipment layout was suggested. The outlets of 3 discharging equipments were maintained in the same straight line, so the dry ash bulk machine was arranged in the center line of each ash silos, the 2 wet mixers were arranged with center line of ash silo into 45° angle. The actual operating results show that the new process layout makes the arrangment of discharge equipments on the ash silo discharging layer more simplified and feasible.%为了解决火电厂灰库卸料层设备布置困难的问题,根据卸料层设备布置的基本原则,提出一种新的卸料设备的布置方式,即保持3个卸料设备的出料口布置在同一条直线的基础上,将干灰散装机仍布置在每座灰库的中心线上,将2台湿式搅拌机均与灰库中心线成45°夹角布置.实际运行效果表明,新的工艺布置方式使灰库卸料层设备布置曼简化、可行.

  13. Preventive Maintenance Handbook. Audiovisual Equipment.

    Science.gov (United States)

    Educational Products Information Exchange Inst., Stony Brook, NY.

    The preventive maintenance system for audiovisual equipment presented in this handbook is designed by specialists so that it can be used by nonspecialists in school sites. The report offers specific advice on saftey factors and also lists major problems that should not be handled by nonspecialists. Other aspects of a preventive maintenance system…

  14. Hydraulic turbines and auxiliary equipment

    Energy Technology Data Exchange (ETDEWEB)

    Luo Gaorong [Organization of the United Nations, Beijing (China). International Centre of Small Hydroelectric Power Plants

    1995-07-01

    This document presents a general overview on hydraulic turbines and auxiliary equipment, emphasizing the turbine classification, in accordance with the different types of turbines, standard turbine series in China, turbine selection based on the basic data required for the preliminary design, general hill model curves, chart of turbine series and the arrangement of application for hydraulic turbines, hydraulic turbine testing, and speed regulating device.

  15. Effect of membrane hydrophilization on ultrafiltration performance for biomolecules separation

    Energy Technology Data Exchange (ETDEWEB)

    Susanto, H., E-mail: heru.susanto@undip.ac.id [Department of Chemical Engineering, Universitas Diponegoro, Jl. Prof. Sudarto-Tembalang, Semarang (Indonesia); Roihatin, A.; Aryanti, N.; Anggoro, D.D. [Department of Chemical Engineering, Universitas Diponegoro, Jl. Prof. Sudarto-Tembalang, Semarang (Indonesia); Ulbricht, M. [Lehrstuhl fuer Technische Chemie, Universitaet Duisburg-Essen, Germany, Universitaetstr. 5, Essen (Germany)

    2012-10-01

    fouling ultrafiltration (UF) membranes. Black-Right-Pointing-Pointer We characterized the membranes before and after modification. Black-Right-Pointing-Pointer We examined the unmodified and modified membranes for biomolecules filtration. Black-Right-Pointing-Pointer All the modifications changed the membrane characteristics and the membrane performance. Black-Right-Pointing-Pointer All the modifications resulted in UF membranes having higher resistance towards fouling.

  16. Effect of membrane hydrophilization on ultrafiltration performance for biomolecules separation

    International Nuclear Information System (INIS)

    characterized the membranes before and after modification. ► We examined the unmodified and modified membranes for biomolecules filtration. ► All the modifications changed the membrane characteristics and the membrane performance. ► All the modifications resulted in UF membranes having higher resistance towards fouling.

  17. 基于大数据的舰船装备维修保障信息分析系统设计%Design of Ship Equipment Maintenance Information Analysis System Based on Big Data

    Institute of Scientific and Technical Information of China (English)

    李伟; 金国庆

    2016-01-01

    To meet requirements of the information collection ,storage ,analysis and application of the ship equipment maintenance ,the design of analysis system for ship equipment maintenance information based on big data is proposed .The scheme includes four aspects ,including system design ,system structure design ,system function design and system database design .System uses Hadoop cluster component storage ,calculation and analysis of massive amounts of data in the bottom . at the top by interfaces it directly calls the underlying storage and computing power .So functions of data management ,data query ,data analysis and processing for the massive ship equipment maintenance information can be realized .%针对舰船装备维修保障信息采集、存储、分析与应用的需求,提出了基于大数据处理技术的舰船装备维修保障信息分析系统的设计方案。方案中包括系统总体设计、系统结构设计、系统功能设计和系统数据库设计四个方面。系统在底层使用 Hadoop 集群组件存储、计算和分析海量数据信息,在高层通过接口直接透明的调用底层存储与计算能力,从而实现系统对海量舰船装备维修保障信息的基础数据管理、数据统计查询和数据分析处理的功能。

  18. 基于GB9706.1的医用电气设备的设计要点分析%Analysis of the Key Points in Design of Medical Electrical Equipment Based on GB9706.1

    Institute of Scientific and Technical Information of China (English)

    李庆雨

    2015-01-01

    In combination with the standard GB 9706.1-2007 Medical Electrical Equipment Part 1:General Safety Requirements, this paper summarized and analyzed the principle and key points in design of medical electrical equipment from the perspective of safety, including design of power supply, application, over-current protection devices, equipment structure and layouts, interfaces as well as the requirements of hazard prevention and bio-safety.%本文主要从安全角度出发,结合标准GB9706.1-2007《医用电气设备第1部分:安全通用要求》,总结并分析了医用电气设备应遵循的设计原则及产品设计阶段需要重点考虑的内容,包括电源部分设计、应用部分设计、过电流保护装置设计、设备结构和布局设计、接口设计、对危险的防护及生物安全性要求。

  19. Analysis of the Key Points in Design of Medical Electrical Equipment Based on GB9706.1%基于GB9706.1的医用电气设备的设计要点分析

    Institute of Scientific and Technical Information of China (English)

    李庆雨

    2015-01-01

    In combination with the standard GB 9706.1-2007 Medical Electrical Equipment Part 1:General Safety Requirements, this paper summarized and analyzed the principle and key points in design of medical electrical equipment from the perspective of safety, including design of power supply, application, over-current protection devices, equipment structure and layouts, interfaces as well as the requirements of hazard prevention and bio-safety.%本文主要从安全角度出发,结合标准GB9706.1-2007《医用电气设备第1部分:安全通用要求》,总结并分析了医用电气设备应遵循的设计原则及产品设计阶段需要重点考虑的内容,包括电源部分设计、应用部分设计、过电流保护装置设计、设备结构和布局设计、接口设计、对危险的防护及生物安全性要求。

  20. Design and Experiment on Dairy Cow Precise Feeding Equipment Based on MCU%基于单片机的奶牛精确饲喂装备设计与试验

    Institute of Scientific and Technical Information of China (English)

    李继成; 高振江; 肖红伟; 蒙贺伟; 坎杂

    2011-01-01

    设计了以计算机为信息管理平台,以单片机为数据处理和控制平台,利用无线射频识别技术进行个体识别的奶牛精确饲喂装备.建立了装备的工作参数并进行了精度验证.通过一个月的饲喂试验表明,该装备技术可显著提高奶牛产奶量及其品质,使奶牛平均日单产提高3.9 kg,且牛奶平均脂肪含量为3.74 g/(100 g),平均蛋白含量为2.98 g/(100 g).%Based on the technology of MCU, one kind of dairy cow precise feeding equipment was designed. This kind of equipment used computer as information management platform, MCU as data processing and control platform, and used the RFID technology to identify dairy cows. The working parameters of the equipment were established and the feeding accuracy of the equipment was verified. By using the equipment, one-month feeding experiment in the dairy cow farm was conducted. The results showed that the milk production per day was increased by 3. 9 kg, and the average fat content of milk was 3. 74 g/ ( 100 g) , the average protein content of milk was 2. 98 g/( 100 g) .

  1. The Design and Implementation of Equipment Requirement Argumentation Project Management System Based on Worklfow%基于工作流的装备需求论证项目管理系统的设计与实现

    Institute of Scientific and Technical Information of China (English)

    陈彦武; 张学波; 高永明; 胡欣杰; 吴止锾

    2014-01-01

    针对目前装备需求论证流程缺少科学的方法论指导、缺少规范的管理机制、信息文档不便于整理、装备需求论证各要素之间相互关系复杂且动态多变等问题,基于工作流技术,设计并实现了一套支持装备需求论证的项目管理系统,该系统能够以在线方式辅助装备需求论证人员基于定义好的论证流程开展武器装备的需求论证工作,并提供了论证进度监控等功能,提高了工作效率,安全性高。%The currently process of equipment requirement argumentation lacks of scientific methodology, lacks of standardized management mechanism, the information and document is not easily to organize, and the interrelationship of various elements of equipment requirement argumentation is complex and dynamic, against these questions, the paper that is based on workflow technology designs and implements a set of project management system which supports equipment requirement argumentation. The system can aid equipment requirement argumentation staff to carry out requirement argumentation studies of equipment on line basing on defined argumentation processes, and provides a function of argumentation progress and other function, improves work efficiency and safety.

  2. 基于医疗设备故障报告的医疗设备潜在设计缺陷研究%A Research on the Identiifcation of Latent Design Flaws Based on the Medical Equipment Fault Report

    Institute of Scientific and Technical Information of China (English)

    王群峰

    2016-01-01

    目的:探讨利用医疗设备故障报告分析医疗设备潜在设计缺陷的可行性。方法对相关医疗设备的维护数据进行分析,找出未发现故障(NFF)报告率较高的医疗设备;然后采用半结构化访谈评估NFF报告率较高的医疗设备潜在的设计缺陷;最后再对NFF报告率较高的医疗设备进行可用性测试,以验证其是否存在设计缺陷。结果医疗设备维护数据分析结果显示,有4种医疗设备的NFF报告率较高。半结构化访谈评估结果表明,可用性问题、设备附件问题、间歇性故障和环境问题等导致了这些设备的NFF报告率显著升高。其中两种医疗设备的可用性测试结果表明,这两种设备确实存在设计缺陷。结论潜在的可用性相关设计缺陷会显著升高医疗设备的NFF报告率,而通过对NFF报告率较高的医疗设备的维护数据进行分析则可以找出医疗设备的潜在设计缺陷。%ObjectiveTo investigate the feasibility of analyzing the latent design flaws of medical equipment with the uses of the medical equipment fault report.Methods An analysis of the relevant medical equipment maintenance data was conducted to identify devices with a high no fault found (NFF) reporting frequency. Subsequently, the semi-structured interview was performed in order to identify potential defects in the design in the medical equipment with higher NFF reporting frequency. Finally, the feasibility test was conducted in order to validate if there exist any defect in the design viatesting latent feasibility of the medical equipment with a higher frequency of NFF reporting.Results The analysis of medical equipment maintenance data identiifed four devices with a high NFF reporting frequency. The semi-structured interviews and the feasibility testing revealed that usability issues caused a signiifcant portion of the NFF reports. Other factors suspected to contribute to the increased NFF reporting

  3. Anti-cross-infection Design and Standard Requirements of Dental Devices and Equipments%口腔器械设备防交叉感染设计与标准要求

    Institute of Scientific and Technical Information of China (English)

    李丹荣

    2013-01-01

    This paper analyzed the main factors that cause cross-infection of oral clinical, and presented the design requirements of anti-cross-infection dental devices and equipments. It focused on the requirements of dental devices and equipments standards involved in anti-cross-infection, as wel as the latest international standardization progress.%  本文分析了引起口腔临床交叉感染的主要因素,提出了口腔器械设备防交叉感染的设计要求,重点讲述了口腔器械设备涉及防交叉感染的标准要求,以及国际最新标准化进展。

  4. Anti-cross-infection Design and Standard Requirements of Dental Devices and Equipments%口腔器械设备防交叉感染设计与标准要求

    Institute of Scientific and Technical Information of China (English)

    李丹荣

    2013-01-01

      本文分析了引起口腔临床交叉感染的主要因素,提出了口腔器械设备防交叉感染的设计要求,重点讲述了口腔器械设备涉及防交叉感染的标准要求,以及国际最新标准化进展。%This paper analyzed the main factors that cause cross-infection of oral clinical, and presented the design requirements of anti-cross-infection dental devices and equipments. It focused on the requirements of dental devices and equipments standards involved in anti-cross-infection, as wel as the latest international standardization progress.

  5. 某型火炮火控系统综合控制箱测试设备的设计研究磁%Design of Test Equipment of the Comprehensive Control Box of A Gun's Fire Control System

    Institute of Scientific and Technical Information of China (English)

    王海辉

    2016-01-01

    运用虚拟仪器技术和PXI总线技术对某型火炮火控系统综合控制箱检测设备的设计进行了研究。设计的检测设备能够完成对综合控制箱进行部件级的性能检测、故障诊断与模拟、维修支持等功能。%A test equipment is designed for comprehensive control box of certain gun's fire control system based on PXI bus and virtual instrument technology .This test equipment has the function of performance test ,fault diagnosis and simula‐tion ,maintenance support for comprehensive control box on component‐level .

  6. 装备健康管理学习型组织设计%Design of Equipment Health Management Learning Organization

    Institute of Scientific and Technical Information of China (English)

    穆彤娜; 师玉峰; 秦翔宇

    2013-01-01

    构建了由学习、人员、结构和知识4个子系统组成的装备健康管理学习型组织模型;将装备健康管理学习型组织划分为决策层、管理层和执行层3个层次,提出建立贯穿3个层次的装备健康管理推进组织;在此基础上以现有装备管理机构为依托,对装备健康管理组织进行机构设置,包括决策机构、监管机构、作业机构、技术支援机构、装备研发机构和装备健康管理推进机构,从而保证装备健康管理活动的顺利运行。%Equipment health management (EHM ) learning organization model composing of learning ,personnel ,structure and knowledge subsystems is constructed;EHM learning organization is divided into decision-making level ,administrant level and executive level , the advice of building EHM impellent organization running through three levels is brought forward ;based on existing e-quipment organization ,EHM organization is set up ,including decision-making organization ,supervi-sory organization ,work organization ,technical support organization ,equipment research organization and EHM impellent organization ,and thereby EHM activity can run successfully .

  7. Constructing Optimal Coarse-Grained Sites of Huge Biomolecules by Fluctuation Maximization.

    Science.gov (United States)

    Li, Min; Zhang, John Zenghui; Xia, Fei

    2016-04-12

    Coarse-grained (CG) models are valuable tools for the study of functions of large biomolecules on large length and time scales. The definition of CG representations for huge biomolecules is always a formidable challenge. In this work, we propose a new method called fluctuation maximization coarse-graining (FM-CG) to construct the CG sites of biomolecules. The defined residual in FM-CG converges to a maximal value as the number of CG sites increases, allowing an optimal CG model to be rigorously defined on the basis of the maximum. More importantly, we developed a robust algorithm called stepwise local iterative optimization (SLIO) to accelerate the process of coarse-graining large biomolecules. By means of the efficient SLIO algorithm, the computational cost of coarse-graining large biomolecules is reduced to within the time scale of seconds, which is far lower than that of conventional simulated annealing. The coarse-graining of two huge systems, chaperonin GroEL and lengsin, indicates that our new methods can coarse-grain huge biomolecular systems with up to 10 000 residues within the time scale of minutes. The further parametrization of CG sites derived from FM-CG allows us to construct the corresponding CG models for studies of the functions of huge biomolecular systems. PMID:26930392

  8. Different size biomolecules anchoring on porous silicon surface: fluorescence and reflectivity pores infiltration comparative studies

    Energy Technology Data Exchange (ETDEWEB)

    Giovannozzi, Andrea M.; Rossi, Andrea M. [National Institute for Metrological Research, Thermodynamic Division, Strada delle Cacce 91, 10135 Torino (Italy); Renacco, Chiara; Farano, Alessandro [Ribes Ricecrhe Srl, Via Lavoratori Vittime del Col du Mont 24, 11100 Aosta (Italy); Derosas, Manuela [Biodiversity Srl, Via Corfu 71, 25124 Brescia (Italy); Enrico, Emanuele [National Institute for Metrological Research, Electromagnetism Division, Strada delle Cacce 91, 10135 Torino (Italy)

    2011-06-15

    The performance of porous silicon optical based biosensors strongly depends on material nanomorphology, on biomolecules distribution inside the pores and on the ability to link sensing species to the pore walls. In this paper we studied the immobilization of biomolecules with different size, such as antibody anti aflatoxin (anti Aflatox Ab, {proportional_to}150 KDa), malate dehydrogenase (MDH, {proportional_to}36KDa) and metallothionein (MT, {proportional_to}6KDa) at different concentrations on mesoporous silicon samples ({proportional_to}15 nm pores diameter). Fluorescence measurements using FITC- labeled biomolecules and refractive index analysis based on reflectivity spectra have been employed together to detect the amount of proteins bound to the surface and to evaluate their diffusion inside the pores. Here we suggest that these two techniques should be used together to have a better understanding of what happens at the porous silicon surface. In fact, when pores dimensions are not perfectly tuned to the protein size a higher fluorescence signal doesn't often correspond to a higher biomolecules distribution inside the pores. When a too much higher concentration of biomolecule is anchored on the surface, steric crowd effects and repulsive interactions probably take over and hinder pores infiltration, inducing a small or absent shift in the fringe pattern even if a higher fluorescence signal is registered. (copyright 2011 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim) (orig.)

  9. From biominerals to biomaterials: the role of biomolecule-mineral interactions.

    Science.gov (United States)

    Perry, Carole C; Patwardhan, Siddharth V; Deschaume, Olivier

    2009-08-01

    Interactions between inorganic materials and biomolecules at the molecular level, although complex, are commonplace. Examples include biominerals, which are, in most cases, facilitated by and in contact with biomolecules; implantable biomaterials; and food and drug handling. The effectiveness of these functional materials is dependent on the interfacial properties, i.e. the extent of molecular level 'association' with biomolecules. The present article gives information on biomolecule-inorganic material interactions and illustrates our current understanding using selected examples. The examples include (i) mechanism of biointegration: the role of surface chemistry and protein adsorption, (ii) towards improved aluminium-containing materials, and (iii) understanding the bioinorganic interface: experiment and modelling. A wide range of experimental techniques (microscopic, spectroscopic, particle sizing, thermal methods and solution methods) are used by the research group to study interactions between (bio)molecules and molecular and colloidal species that are coupled with computational simulation studies to gain as much information as possible on the molecular-scale interactions. Our goal is to uncover the mechanisms underpinning any interactions and to identify 'rules' or 'guiding principles' that could be used to explain and hence predict behaviour for a wide range of (bio)molecule-mineral systems. PMID:19614576

  10. Room temperature ionic liquids interacting with bio-molecules: an overview of experimental and computational studies

    Science.gov (United States)

    Benedetto, Antonio; Ballone, Pietro

    2016-03-01

    We briefly review experimental and computational studies of room temperature ionic liquids (RTILs) interacting with important classes of biomolecules, including phospholipids, peptides and proteins, nucleic acids and carbohydrates. Most of these studies have been driven by the interest for RTILs applications as solvents. Thus, available experimental data cover primarily thermodynamic properties such as the reciprocal solubility of RTILs and bio-molecules, as well as phase boundaries. Less extensive data are also available on transport properties such as diffusion and viscosity of homogeneous binary (RTILs/biomolecules) and ternary (RTIL/biomolecules/water) solutions. Most of the structural information at the atomistic level, of interest especially for biochemical, pharmaceutical and nanotechnology applications, has been made available by molecular dynamics simulations. Major exceptions to this statement are represented by the results from NMR and circular dichroism spectroscopy, by selected neutron and X-ray scattering data, and by recent neutron reflectometry measurements on lipid bilayers on surfaces, hydrated by water-RTIL solutions. A final section of our paper summarizes new developments in the field of RTILs based on amino acids, that combine in themselves the two main aspects of our discussion, i.e. ionic liquids and bio-molecules.

  11. 制冷空调设备绿色设计的技术和实践探讨%Technical and Practical Discussions on Green Design of Refrigeration and Air Conditioning Equipments

    Institute of Scientific and Technical Information of China (English)

    朱斌祥; 张缓缓; 曲本连; 彭飞; 李韶强

    2015-01-01

    空调行业作为能源消耗和环境污染的重要源流,对于节能环保承担着重要责任。制冷空调设备绿色设计的应用研究日益受到人们的重视。本文指出了制冷空调产品进行绿色设计的必要性,分析了制冷空调绿色设计中的主要因素及主要内容,对于目前制冷空调产品提出了相应的绿色设计方法,还提出了绿色设计在制冷空调产品中的应用策略,以及绿色产品的评价指标。%As an important part of energy consumption and environment pollution, the air conditioning industry takes a great responsibility for energy saving and environment protection. More and more attentions have been paid on the application investigation in the green design of refrigeration and air conditioning equipments. In the paper the necessity to conduct the green design of refrigeration and air conditioning equipments is pointed out. A series of major factors and technologies are analyzed. The green design methods are proposed for the practical refrigeration and air conditioning equipment. In addition, the application strategy of green design in the air conditioning and refrigeration field is presented and the evaluation indicators on green products are concluded.

  12. 一种膨胀性快速检测装置的设计%Design of a Quick Expansion Detection Equipment

    Institute of Scientific and Technical Information of China (English)

    王士民

    2013-01-01

      介绍一种膨胀性快速检测装置,用于非金属矿物膨润土膨胀性能的自动快速检测。优化该装置的离心机系统,操作时按照标准要求将定量蒸馏水、膨润土粉体、药剂按顺序加入离心管中,振荡、离心、读数,装置采用离心原理,将重力场下24 h的检测时间,缩短到10 min,可以快速定性产品质量,同时使技术人员摆脱繁重的检测工作。该装置行业推广性强。%A kind of quick expansion detection equipment used for bentonite is introduced.The device is a optimization centri-fuge system.According to the standard, distilled water, bentonite powder and agent are mixed into the centrifuge tube and then oscillation, centrifugal, reading.Using centrifugal principle of the equipment, the quality of the products the can judge quickly and the test time can be in 10min instead of 24h.Meanwhile it could get rid of the heavy test works to technician.It will be widely used in the industry.

  13. OEE数据分析的设计与应用%Design and application of OEE data analysis in equipment management

    Institute of Scientific and Technical Information of China (English)

    梁岳

    2014-01-01

    基于在设备管理工作中应用设备综合效率(OEE)分析的目的,通过对OEE理论进行研究,并结合生产管控系统的实际情况,采用了将六大损失归类到时间开动率、性能开动率、合格品率三大指标中,再针对六大损失的末梢因素进行设备状态及其影响原因判别的方法,建立起OEE的数据模型;进一步结合QC工具的使用可以有效地对OEE数据进行分析,找到提高设备效率的思路与对策。%In the purpose of practicing Overall Equipment Effectiveness (OEE) in equipment management, the author builds up a model of OEE. First is classifying six losses by Time Utilization Ratio, Device Performance Ratio and Product Qualification Ratio. Second is identifying the equipment’s status including its cause by the end factors of the six losses. Also, by using QC tools to analysing OEE data can provide guidance for the maintenance operation.

  14. 电信设备软件自动升级设计与实现%Design and Implementation of the Software Automatic Upgrading for Telecom Equipments

    Institute of Scientific and Technical Information of China (English)

    谭亚科

    2013-01-01

    针对电信设备在日常维护中需要人工对各种业务板进行频繁的软件版本升级的情况,作者提出了自动升级的设想。通过在系统中增加一个自动升级服务器,同时在设备主控板中增加相应的版本检测算法,实现对各类业务板的软件进行检测并自动升级的功能,文中一并给出了它的实现方式。%Aiming at the situation that the software versions of various service boards need to be upgraded frequently by manual in the routine maintenance of telecom equipments, the paper proposes a method to upgrade the software version automatically. An automatic upgrading server is introduced in telecom system; also a software version detection algorithm is added in the system control board, so as to implement the software version detection and automatic upgrading functions for all kinds of service boards in telecom equipment.

  15. 面向寿命周期的装备资源性设计策略研究%A Study on Life Cycle-Oriented Equipment Resource-Ability Design Strategy

    Institute of Scientific and Technical Information of China (English)

    刘世伦; 倪明仿; 王生凤; 辛涛

    2011-01-01

    Resource-ability is an attribute which is closely related to resources and the environment. Resource-ability design is a fundamental way to implement equipment resource-ability. Resource-ability design should fully account for the equipment total life cycle that from resource acquisition to retired or scrap phrase, and implement different layout strategies in terms of the characteristics for different stages. Considering the constraints of traditional fossil energy, metal resources, environmental bearing capacity, and other respects that we are faced with,resource-oriented design tends to select the material and energy type. It enables one to select the type that is of the ability to achieve sustainability and select green clean material or energy type,which can reduce the dependence of equipment on scarce resources, improve the environment-friendly attribute of equipment, and improve the energy consumption structure as well. Manufacture oriented design primarily places particular emphasis on the design for manufacturability in order to produce the equipment with the lowest expenses, consumption and the shortest time, and achieve necessary quality and performance demand. Packaging and transporting-oriented design primarily places particular emphasis on the design for green packageability. Maintenance-support oriented design puts particular emphasis on the design for the level of energy consumption and green maintainability, including the control and optimization of the energy consumption level of equipment, structure simplification, maintaining reachability,testability, prevention against error, resource recycling ability, and environmental and personnel security. Upgrade and transform oriented design puts particular emphasis on the design for extensibility. It is mainly concerned with changing and installing additional and transforming functions of the equipment system in the future during the course of design, so as to take relevant design measures to guarantee

  16. Electrical equipment qualification

    International Nuclear Information System (INIS)

    Electrical equipment qualification research programs being carried out by CEA, JAERI, and Sandia Laboratories are discussed. Objectives of the program are: (1) assessment of accident simulation methods for electrical equipment qualification testing; lower coarse (2) evaluation of equipment aging and accelerated aging methods; (3) determine radiation dose spectrum to electrical equipment and assess simulation methods for qualification; (4) identify inadequacies in electrical equipment qualification procedures and standards and potential failure modes; and (5) provide data for verifying and improving standards, rules and regulatory guides

  17. Radical Reactions in the Gas Phase: Recent Development and Application in Biomolecules

    Directory of Open Access Journals (Sweden)

    Yang Gao

    2014-01-01

    Full Text Available This review summarizes recent literature describing the use of gas phase radical reactions for structural characterization of complex biomolecules other than peptides. Specifically, chemical derivatization, in-source chemical reaction, and gas phase ion/ion reactions have been demonstrated as effective ways to generate radical precursor ions that yield structural informative fragments complementary to those from conventional collision-induced dissociation (CID. Radical driven dissociation has been applied to a variety of biomolecules including peptides, nucleic acids, carbohydrates, and phospholipids. The majority of the molecules discussed in this review see limited fragmentation from conventional CID, and the gas phase radical reactions open up completely new dissociation channels for these molecules and therefore yield high fidelity confirmation of the structures of the target molecules. Due to the extensively studied peptide fragmentation, this review focuses only on nonpeptide biomolecules such as nucleic acids, carbohydrates, and phospholipids.

  18. Detection of biomolecules and bioconjugates by monitoring rotated grating-coupled surface plasmon resonance

    CERN Document Server

    Szalai, Aniko; Somogyi, Aniko; Szenes, Andras; Banhelyi, Balazs; Csapo, Edit; Dekany, Imre; Csendes, Tibor; Csete, Maria

    2016-01-01

    Plasmonic biosensing chips were prepared by fabricating wavelength-scaled dielectric-metal interfacial gratings on thin polycarbonate films covered bimetal layers via two-beam interference laser lithography. Lysozyme (LYZ) biomolecules and gold nanoparticle (AuNP-LYZ) bioconjugates with 1:5 mass ratio were seeded onto the biochip surfaces. Surface plasmon resonance spectroscopy was performed before and after biomolecule seeding in a modified Kretschmann-arrangement by varying the azimuthal and polar angles to optimize the conditions for rotated grating-coupling. The shift of secondary and primary resonance peaks originating from rotated grating-coupling phenomenon was monitored to detect the biomolecule and bioconjugate adherence. Numerical calculations were performed to reproduce the measured reflectance spectra and the resonance peak shifts caused by different biocoverings. Comparison of measurements and calculations proved that monitoring the narrower secondary peaks under optimal rotated-grating coupling ...

  19. 某型飞机前起落架顶起装置设计和实现%Design and Implementation of Nose Landing Gear Jack-up Equipment of an Aircraft

    Institute of Scientific and Technical Information of China (English)

    顾星

    2014-01-01

    The article introduces an aircraft nose landing gear jack-up equipment which is used for simulating an aircraft's nose landing gear swerving test. The main scheme is introduced and the equipment is driven by air. The jack-up actuator is designed as body with three supports and road wheels, this kind of design can not only provide the enough strength and stiffness but also be moved easily. The electrical control section controls the magnetic exchange valve to supply air for the double-acting cylinder, this can achieve the actuator up and down. The equipment is sutably designed with not too much structures and it can be easily maintained, operated and moved, it also has breakdown protection, limit protection and urgency outage protection.%该文介绍了为配合模拟某型飞机的前轮转弯试验设计的前起落架顶起装置,给出了其总体方案。装置采用气源驱动,顶起执行机构采用三角支撑架体并配有行走轮,保证机构强度和刚度的同时又便于移动,电气控制部分控制电磁换向阀向双作用气缸供气,实现顶起机构的顶起和放下。整个装置结构紧凑、布局合理、维护简单、操作方便、移动灵活,并有故障保护、限位保护和紧急断电保护功能。

  20. 某信号控制与处理设备的热设计及结构优化%Thermal Design and Structure Optimization of a Signal Controlling and Processing Equipment

    Institute of Scientific and Technical Information of China (English)

    陈思; 谢天宇; 吕强

    2012-01-01

    热设计是器件、设备和系统可靠性设计的一项主要内容。文中介绍了某信号控制与处理设备的热设计过程。从单机、模块层面,分别进行了相关热设计。强迫风冷是常用的冷却方式。在多风机的情况下,风道的构建、隔离都是需要考虑的方面。使用Flotherm软件对单机模型进行了热仿真。热仿真对结构设计可起到指导作用,可以优化结构,使单机结构更加合理,散热更加有效,提高了单机的可靠性。%Thermal design is important in reliability design of component,equipment and system.In this paper,the thermal design at the level of cabinet and modules for a signal controlling and processing equipment is introduced.Forced convection is an usual cooling method.Airflow′s routing and separating should be considered under the condition of using several fans in the cabinet.The thermal simulation is conducted with the software of Flotherm,not only to do the thermal analysis of the cabinet,but also to optimize the structure,which makes the structure more reasonable,the cooling more efficient,the equipment more reliable.

  1. Renewal of radiological equipment.

    Science.gov (United States)

    2014-10-01

    In this century, medical imaging is at the heart of medical practice. Besides providing fast and accurate diagnosis, advances in radiology equipment offer new and previously non-existing options for treatment guidance with quite low morbidity, resulting in the improvement of health outcomes and quality of life for the patients. Although rapid technological development created new medical imaging modalities and methods, the same progress speed resulted in accelerated technical and functional obsolescence of the same medical imaging equipment, consequently creating a need for renewal. Older equipment has a high risk of failures and breakdowns, which might cause delays in diagnosis and treatment of the patient, and safety problems both for the patient and the medical staff. The European Society of Radiology is promoting the use of up-to-date equipment, especially in the context of the EuroSafe Imaging Campaign, as the use of up-to-date equipment will improve quality and safety in medical imaging. Every healthcare institution or authority should have a plan for medical imaging equipment upgrade or renewal. This plan should look forward a minimum of 5 years, with annual updates. Teaching points • Radiological equipment has a definite life cycle span, resulting in unavoidable breakdown and decrease or loss of image quality which renders equipment useless after a certain time period.• Equipment older than 10 years is no longer state-of-the art equipment and replacement is essential. Operating costs of older equipment will be high when compared with new equipment, and sometimes maintenance will be impossible if no spare parts are available.• Older equipment has a high risk of failure and breakdown, causing delays in diagnosis and treatment of the patient and safety problems both for the patient and the medical staff.• Every healthcare institution or authority should have a plan for medical imaging equipment upgrade or replacement. This plan should look forward a

  2. Armature Guide Ring Automation Assembly Equipment Feeding Mechanism Design Based on TRIZ%基于 TRIZ 的导向环自动装配设备上料机构设计

    Institute of Scientific and Technical Information of China (English)

    周为; 王剑彬; 向友

    2016-01-01

    针对雨刮器电机自动化生产线配套设备,电枢导向环自动装配设备结构设计中如何高效、稳定供料的问题,提出运用T RIZ创新设计方法中的冲突解决原理进行电枢导向环自动装配设备的上料机构设计。通过分析上料机构功能设计需求与T RIZ中39个工程参数的关系,建立上料机构的矛盾矩阵,用冲突解决原理进行分析,找到相应的原理解,结合传统设计经验提出设计方案并评估,最终确定了电枢导向环自动装配设备上料机构的设计方案。%To design an efficient and stable armature guide ring automation assembly equipment in wiper motor automation production line ,the paper put forward using the conflict resolution principle of TRIZ to design the feeding mechanism .Through the analysis on the relationship of the functional design requirements and 39 engineering parameters in TRIZ ,the contradictions matrix of feeding mechanism was set up ,and analyzed by the conflict resolution principle ,the corresponding original solution was found .Combined with traditional design experience ,the design scheme was put forward and evaluated ,eventually the armature guide ring automation assembly equipment feeding mechanism was designed .

  3. Non-conventional Indoor GIS Layout Design of 220kV Distribution Equipment in Guangzhou Xintang Power Plant%广州新塘电厂220 kV屋内GIS非常规布置的设计

    Institute of Scientific and Technical Information of China (English)

    唐柳燕

    2014-01-01

    ∶针对广州新塘电厂2×330MW机组工程厂区布置的特殊性及局限性,文章详细分析论述了220kV配电装置采用屋内GIS型式非常规布置的设计过程及其特点,提出合适的布置方案,解决了220kV配电装置占地及出线问题,为类似工程提供借鉴。%The design and the characteristics of the non-conventional indoor GIS layout of 220kV distribution equip-ment were discussed and analyzed in the paper based on the particularity and limitation of plant layout of Guangzhou Xintang power plant, and a reasonable layout was proposed which solves the land occupation and outgoing line prob-lems of the 220kV distribution equipment and can be well referenced by similar projects.

  4. The Design and Realization of Wireless Management System of Port Machinery Equipment%港口机械设备无线管理系统的设计与实现

    Institute of Scientific and Technical Information of China (English)

    李胜永; 张智华; 房世龙; 安天生

    2014-01-01

    On the basis of analyzing the characteristics of the port machinery equipment, the authors use the wireless transmission module NRF24L01 to achieve the wireless transmission of information in port e-quipment management, and also complete a node hardware circuit design, software configuration and low-power node implementation strategy. This plan has passed the simple test of wireless communication which provides an integration solution to port machinery equipment management in port construction of Internet of Things.%在分析港口机械设备特点的基础上,采用NRF24L01无线传输模块实现了港口设备管理信息的无线传输,并进行了节点硬件电路设计、软件配置及低功耗设计。该组建方案通过了无线通信的简单测试,为物联网港口建设中港口机械设备管理提供了一种有效方法。

  5. 基于虚拟技术的矿山设备维修训练系统设计研究%Design of maintenance training system for mining equipments based on virtualization technology

    Institute of Scientific and Technical Information of China (English)

    金葵

    2011-01-01

    以改进矿山设备维修训练手段为目的,通过对矿山设备虚拟维修系统开发关键技术的分析,提出了基于虚拟技术的矿山设备维修训练系统结构设计思路;并将建立好的设备训练系统应用于矿山维修训练中,达到了降低训练费用、缩短训练时间及提高训练效果的目的.%In order to improve the maintenance training methods for mining equipments, after analysing key technologies of developing virtual maintenance system for mining equipments, the ideas of designing the structure of maintenance training system for mining equipments based on virtualization technology are proposed.In addition, the established maintenance training system is applied to maintenance training in a mine, thus training costs decrease, training duration shortens and training effects improve.

  6. Innovation and Development Strategies on Products for Equipment Manufacturing Industry Based on Industrial Design%基于工业设计的装备制造业产品创新开发策略

    Institute of Scientific and Technical Information of China (English)

    虞世鸣

    2012-01-01

    By cross integration and comprehensive analysis of ergonomics, product semantics, technical aesthetics and brand & culture building, it points out that concepts and methods on accurate and effective industrial design should be applied to product innovation and development in equipment manufacturing industry with establishment of correlative design philosophy; It also proposes the strategy on product innovation and development by taking invention patent and conceptual design library etc. as the key objectives in equipment manufacturing industry.%通过对人机工程学、产品语义学、技术审美学、品牌文化构建等交叉融合和综合分析,指出应准确有效地将工业设计的理念和方法应用到装备制造业产品创新开发中,建立相关的设计原则,提出以发明专利以及概念设计库等为重点目标的装备制造业产品创新开发的策略.

  7. 面向服务的装备远程测试与故障诊断系统的设计%Design of Remote Test and Fault Diagnosis System for Service-Oriented Equipment

    Institute of Scientific and Technical Information of China (English)

    汤宫民; 刘福军; 尹晓虎; 汤潇奕; 梁清果

    2016-01-01

    In view of the requirements of the new equipment maintenance support tecnoiogy,and combining with the characteristics of campaign-level equipment maintenance support organization, the article relies on the resourses of the existing test and fault diagnosis system for campaign-level equipment maintenance support organization. On the basis of demand analysis of equipment remote test and fault diagnosis system, and using the service-oriented architecture thought, the article designs the software architecture and hardware structure of service-oriented remote testing and fault diagnosis system, and analyzes the all business flow layer functions, field test side, communication network and remote technical support center side. The scalability & extensibility of equipment performance test and maintenance fault diagnosis system for campaign-level maintenance support organization are increased, and the real-time performances of remote control and data analysis are improved. And the system can realize the remote control, resourses sharing and information fusion in the true sense, and benefits to respond flexibly the maintenance demand changes for campaign-level equipment maintenance support organization.%针对新型装备维修技术保障需求,本文结合战役级装备维修保障机构特点,依托战役级装备维修机构现有测试和故障诊断系统资源,在对装备远程测试与故障诊断系统需求分析的基础上,利用面向服务的体系架构思想,设计了面向服务的广域分布式远程测试与故障诊断系统软件架构和硬件结构,并对其各业务流层功能和现场测试端、通信网络、远程技术支援中心端进行了分析。对于提高战役级装备性能测试和维修故障诊断系统的伸缩性和扩展性,提高远程控制、数据分析的实时性能,实现真正意义上的远程控制、资源共享和信息融合,有利于修理机构灵活地应对维修需求的变化。

  8. The room of the X-rays equipment for Siti Aminah Hospital Bumi Ayu Central Java has been designed to achieve 125 kV and 200 mA capacity

    International Nuclear Information System (INIS)

    The room of the X-rays equipment for Siti Aminah Hospital Bumi Ayu Central Java has been designed to achieve 125 kV and 200 mA capacity, so as to provide radiation properly during operation. In order to achieve safe radiation exposure to the operator and patient, analysis and calculation are needed regarding time exposure, distance and shield width as required by radiation standard, procedure and principle. The result of calculation are expected to give exact maximum doses both for operator and patients. The shielding of the room, consist of concrete and Pb. (author)

  9. Design of Dual Circuit Power Supply System Based on Medical Equipment%基于医疗设备的双回路供电系统设计

    Institute of Scientific and Technical Information of China (English)

    王燕妮; 张立军; 李传伟

    2015-01-01

    This paper proposes the specific hardware environment and software program by analyzing the use of PLC control system in completing automatic switching principle of double circuit power supply system,in accordance with the working requirements of the distribution system circuit switch and the demands of eliability of power supply system for medical equipment,improving the reliability of the system.%针对医疗设备供电系统的可靠性要求,根据配电系统线路切换的工作要求,分析了利用PLC控制系统完成双回路供电系统的自动切换工作原理,给出了具体的硬件环境和软件程序,增强了系统的可靠性.

  10. 聚醚醚酮精制工艺及设备的设计与运行%Design and operation for process and equipment of polyetheretherketone refining

    Institute of Scientific and Technical Information of China (English)

    王树江

    2012-01-01

    In the process of polyetheretherketone (PEEK) production, reaction products, raw materials, solvents and by - products are mixed together. In order to get the pure PEEK, the polymerization product must be refined. Due to the longer process flow and higher consumption of energy and water, the current process and equipment were improved based on experimental data. The dispersed equipment with single function was integrated together. Firstly, solvent diphenyl sulfone was removed by acetone extraction; then fluoride salts and other water soluble substances were removed through water washing; finally, the pure material was obtained after vacuum drum drying. The above three steps of refining process were performed in the same equipment. Using the improved equipment, the time of PEEK refining is 22 h, the moisture mass fraction of material after drying reaches 0. 02% , and the material powdering rate is only 2. 85%. The practice shows that the improved technology is featured by concentrated process and simple operation, which shortens the refining time by 31 h, reduces energy and water consumption, and greatly improves the production efficiency.%聚醚醚酮生产过程中,反应产物、原料、溶剂及副产物混合在一起,为了得到纯的聚醚醚酮需对其聚合产物进行精制.针对现行生产工艺流程较长、能耗及水耗较大的特点,依据实验数据,对现行工艺、设备进行改进.将分散的、单一功能设备综合在一起,先经丙酮浸取,除去溶剂二苯砜;再经水洗除去氟盐等水溶性物质;最后经过真空转筒干燥得到纯物料,上述3步精制过程在同一设备中实现.使用改进后设备进行生产,聚醚醚酮精制时间为22 h,并且干燥后物料含水质量分数达到0.02%,物料的粉化率也仅为2.85%.经实际生产证明,改进后工艺集中,操作简化,精制时间较原工艺缩短31 h,同时降低了能耗,节约超纯水用量,较大程度地提高了生产效率.

  11. Designing Program for Multi-function Optical Fiber and Laser Machining Equipment%光纤激光多功能加工设备设计方案

    Institute of Scientific and Technical Information of China (English)

    吴国良; 李建伟; 郑志强; 曹巍巍

    2012-01-01

    该设备的方案为选配光纤传导的大功率光纤激光器,将聚焦系统连接在机器人手腕上,集成为柔性激光加工设备,运动的执行机构为激光束扫描运动的机器人+工件旋转的转台系统,可以实现各种形状零件的全自动激光加工。%The program is to select a large-powered optical fiber laser for optical fiber transmitting. It connects the focusing system to the wrist of a robot, integrated to be a flexible laser machining equipment, the manipulators are laser beam scanning robot and workpiece rotating floor, which can realize fully automatic laser machining of various-shape parts.

  12. Metal Stable Isotope Tagging: Renaissance of Radioimmunoassay for Multiplex and Absolute Quantification of Biomolecules.

    Science.gov (United States)

    Liu, Rui; Zhang, Shixi; Wei, Chao; Xing, Zhi; Zhang, Sichun; Zhang, Xinrong

    2016-05-17

    The unambiguous quantification of biomolecules is of great significance in fundamental biological research as well as practical clinical diagnosis. Due to the lack of a detectable moiety, the direct and highly sensitive quantification of biomolecules is often a "mission impossible". Consequently, tagging strategies to introduce detectable moieties for labeling target biomolecules were invented, which had a long and significant impact on studies of biomolecules in the past decades. For instance, immunoassays have been developed with radioisotope tagging by Yalow and Berson in the late 1950s. The later languishment of this technology can be almost exclusively ascribed to the use of radioactive isotopes, which led to the development of nonradioactive tagging strategy-based assays such as enzyme-linked immunosorbent assay, fluorescent immunoassay, and chemiluminescent and electrochemiluminescent immunoassay. Despite great success, these strategies suffered from drawbacks such as limited spectral window capacity for multiplex detection and inability to provide absolute quantification of biomolecules. After recalling the sequences of tagging strategies, an apparent question is why not use stable isotopes from the start? A reasonable explanation is the lack of reliable means for accurate and precise quantification of stable isotopes at that time. The situation has changed greatly at present, since several atomic mass spectrometric measures for metal stable isotopes have been developed. Among the newly developed techniques, inductively coupled plasma mass spectrometry is an ideal technique to determine metal stable isotope-tagged biomolecules, for its high sensitivity, wide dynamic linear range, and more importantly multiplex and absolute quantification ability. Since the first published report by our group, metal stable isotope tagging has become a revolutionary technique and gained great success in biomolecule quantification. An exciting research highlight in this area

  13. Metal Stable Isotope Tagging: Renaissance of Radioimmunoassay for Multiplex and Absolute Quantification of Biomolecules.

    Science.gov (United States)

    Liu, Rui; Zhang, Shixi; Wei, Chao; Xing, Zhi; Zhang, Sichun; Zhang, Xinrong

    2016-05-17

    The unambiguous quantification of biomolecules is of great significance in fundamental biological research as well as practical clinical diagnosis. Due to the lack of a detectable moiety, the direct and highly sensitive quantification of biomolecules is often a "mission impossible". Consequently, tagging strategies to introduce detectable moieties for labeling target biomolecules were invented, which had a long and significant impact on studies of biomolecules in the past decades. For instance, immunoassays have been developed with radioisotope tagging by Yalow and Berson in the late 1950s. The later languishment of this technology can be almost exclusively ascribed to the use of radioactive isotopes, which led to the development of nonradioactive tagging strategy-based assays such as enzyme-linked immunosorbent assay, fluorescent immunoassay, and chemiluminescent and electrochemiluminescent immunoassay. Despite great success, these strategies suffered from drawbacks such as limited spectral window capacity for multiplex detection and inability to provide absolute quantification of biomolecules. After recalling the sequences of tagging strategies, an apparent question is why not use stable isotopes from the start? A reasonable explanation is the lack of reliable means for accurate and precise quantification of stable isotopes at that time. The situation has changed greatly at present, since several atomic mass spectrometric measures for metal stable isotopes have been developed. Among the newly developed techniques, inductively coupled plasma mass spectrometry is an ideal technique to determine metal stable isotope-tagged biomolecules, for its high sensitivity, wide dynamic linear range, and more importantly multiplex and absolute quantification ability. Since the first published report by our group, metal stable isotope tagging has become a revolutionary technique and gained great success in biomolecule quantification. An exciting research highlight in this area

  14. Induction of Biomolecules in Mature Leaves of Terminalia arjuna Due to Feeding of Antheraea mylitta Drury

    Directory of Open Access Journals (Sweden)

    G. Abraham

    2004-01-01

    Full Text Available Terminalia arjuna is an important food plant of the tasar silkworm, Antheraea mylitta Drury. In this study, we investigated the induction of biomolecules in mature leaves of these plants subjected to insect feeding. Increase in total tannin content, lipid peroxidation, and trypsin inhibitor activity have been observed in mature leaves damaged by the insects. The growth rate of Vth instar larvae of A. mylitta fed on previously damaged foliage reduced by 87.1%. Induction of biomolecules for defense mechanisms in relation to herbivore damage has been discussed.

  15. Affinity-Mediated Homogeneous Electrochemical Aptasensor on a Graphene Platform for Ultrasensitive Biomolecule Detection via Exonuclease-Assisted Target-Analog Recycling Amplification.

    Science.gov (United States)

    Ge, Lei; Wang, Wenxiao; Sun, Ximei; Hou, Ting; Li, Feng

    2016-02-16

    As is well-known, graphene shows a remarkable difference in affinity toward nonstructured single-stranded (ss) DNA and double-stranded (ds) DNA. This property makes it popular to prepare DNA-based optical sensors. In this work, taking this unique property of graphene in combination with the sensitive electrochemical transducer, we report a novel affinity-mediated homogeneous electrochemical aptasensor using graphene modified glassy carbon electrode (GCE) as the sensing platform. In this approach, the specific aptamer-target recognition is converted into an ultrasensitive electrochemical signal output with the aid of a novel T7 exonuclease (T7Exo)-assisted target-analog recycling amplification strategy, in which the ingeniously designed methylene blue (MB)-labeled hairpin DNA reporters are digested in the presence of target and, then, converted to numerous MB-labeled long ssDNAs. The distinct difference in differential pulse voltammetry response between the designed hairpin reporters and the generated long ssDNAs on the graphene/GCE allows ultrasensitive detection of target biomolecules. Herein, the design and working principle of this homogeneous electrochemical aptasensor were elucidated, and the working conditions were optimized. The gel electrophoresis results further demonstrate that the designed T7Exo-assisted target-analog recycling amplification strategy can work well. This electrochemical aptasensor realizes the detection of biomolecule in a homogeneous solution without immobilization of any bioprobe on electrode surface. Moreover, this versatile homogeneous electrochemical sensing system was used for the determination of biomolecules in real serum samples with satisfying results.

  16. Design and Application of Electric Power Automation Equipment Online Monitoring System%调度自动化设备状态在线监测系统的设计与应用

    Institute of Scientific and Technical Information of China (English)

    刘晖

    2016-01-01

    The current electric power dispatching automation system of equipment maintenance management mainly limited to the configuration of equipment management. In the face of all kinds of unexpected events, there is not an effective early warning in time, so design and make application of dispatching automation equipment status online monitoring system. The system adopts the modular structure design, with real-time monitoring, alarm and remote maintenance, diagnosis, and other functions. After the system is applied in Anhui Chaohu Electric Power Supply Company, realized real-time monitoring and diagnosis of automation equipment operation condition. Alarm through a variety of alarm way in order to make the maintenance personnel process faults in time, effectively ensure the safe and stable and reliable operation of the dispatching automation equipment.%目前电力调度自动化系统对设备的维护管理主要局限于设备的配置管理,面对各种突发性事件不能进行及时、有效预警,为此设计并应用了调度自动化设备状态在线监测系统。该系统采用模块化结构设计,具有实时监测、告警及远程维护、诊断等功能。该系统在安徽省电力公司巢湖市供电公司应用后,实现了对自动化设备运行工况的实时监测和诊断,及时发现故障,并通过多种方式告警,使维护人员及时处理故障,有效保障了调度自动化设备的安全、稳定和可靠运行。

  17. 基于传感器技术的工业设备诊断系统的设计%Design of Industrial Equipment Diagnosing System Based on Sensor Technology

    Institute of Scientific and Technical Information of China (English)

    邹耀宗; 胡文博

    2013-01-01

    随着物联网技术的不断发展,传感器技术得到了不断的完善,已经开始逐步运用到社会的各个方面,但是在工业设备操作现场方面的应用还不算完善.基于对传感器技术的研究,本文设计一种工业设备诊断系统.该系统通过传感器技术可以实时对工业现场设备参数进行检测和查询.由无线传感器网络将采集的信息传递到数据库服务器,最后由上位机进行相应的诊断处理.这样可以减少设备故障带来的危害和损失.%With the development of the internet of things,the sensor technology has been constantly improved,which also begins to apply to all aspects of society,but is not perfect in the industrial equipment diagnosing management.Based on research of the sensor technology,the paper designs an industrial equipment diagnosing system.With sensor technology,the parameters of industrial site equipment can be detected and queried in real time.The wireless sensor network transmits the data to database server,and the data is finally processed by host computer.In this way the loss caused by reducing equipment failure can be reduced.

  18. Lifecycle Management of Safeguards Equipment

    International Nuclear Information System (INIS)

    In recent years, traditional procurement procedures for safeguards equipment have experienced major setbacks that have led to costly and time-consuming re-design and re-evaluation periods, as well as delays in the delivery and deployment of urgently needed equipment. A common element of all encountered problems is the rapid development of technical components. The accelerated pace of 69 safeguards systems development, when coupled with the absence of a disciplined lifecycle approach to design and development, leads to early technical obsolescence as well as the inability to support a safeguards system over its operational lifecycle. This condition is further aggravated by safeguards equipment suppliers who wrestle with economies of scale associated with a unique safeguards market that generally does not provide sufficient margins to stay in business. As a result, international agencies charged with safeguards responsibilities find it difficult to secure the supply of identical safeguards equipment over periods of ten or more years. However, all these problems are merely symptoms of the lack of an integrated lifecycle management approach with early involvement of all parties: vendors and their suppliers, national laboratories and contracted developers, national support programs, and international agencies with nonproliferation responsibilities. The following paper will describe the unique constellation of players within the safeguards community, and why this constellation is a cause of most of the problems inherent in traditional procurement procedures. Further, it will offer a comprehensive lifecycle management approach that will ensure the availability of identical safeguards equipment over its required lifespan (ten to fifteen years). It should be noted that an integrated lifecycle management approach will be difficult to implement and will require a fundamental re-orientation of efforts in: need identification, system design and development, funding, and

  19. WP EMPLACEMENT CONTROL AND COMMUNICATION EQUIPMENT DESCRIPTIONS

    Energy Technology Data Exchange (ETDEWEB)

    N.T. Raczka

    1997-10-02

    The objective and scope of this document are to list and briefly describe the major control and communication equipment necessary for waste package emplacement at the proposed nuclear waste repository at Yucca Mountain. Primary performance characteristics and some specialized design features of the required equipment are explained and summarized in the individual subsections of this document. This task was evaluated in accordance with QAP-2-0 and found not to be quality affecting. Therefore, this document was prepared in accordance with NAP-MG-012. The following control and communication equipment are addressed in this document: (1) Programmable Logic Controllers (PLC's); (2) Leaky Feeder Radio Frequency Communication Equipment; (3) Slotted Microwave guide Communication Equipment; (4) Vision Systems; (5) Radio Control Equipment; and (6) Enclosure Cooling Systems.

  20. Radiological services and imaging equipment management

    International Nuclear Information System (INIS)

    Implementation of a long range capital asset management program in radiological and imaging equipment should be designed to enhance imaging quality, maximise up-time, ensure throughput, reduce cost and ensure patient and operator safety is discussed

  1. 40 CFR 63.1003 - Equipment identification.

    Science.gov (United States)

    2010-07-01

    ... connectors in a designated area or length of pipe subject to the provisions of this subpart are identified as... pressure relief devices equipped with rupture disks, under the provisions of § 63.1011(e) of this...

  2. Composting equipment design and technology for rural refuse disposal%处理农村生活垃圾装置的研制及工艺

    Institute of Scientific and Technical Information of China (English)

    文国来; 王德汉; 李俊飞; 邹璇; 孙艳军

    2011-01-01

    为了探索农村生活垃圾的处理途径,该文研究了一种新型一体化处理生活垃圾的装置及工艺,以广州市番禺区猛涌村生活垃圾为研究对象,进行了2个月的中试试验.研制的堆肥装置分4个小仓,每个小仓容纳垃圾1.56 m3,总容积6.24 m3,抽风机功率为1.1 kW/h,抽风频率为1 d 10次,每次30 min,总时间为5 h,每天总耗电量5.5 kW,能耗低.通过12 d高温发酵,24 d编织袋二次发酵的处理方式,温度能达到60℃的天数在5 d以上,出仓时减容约为40%,堆肥产品质量符合要求,且整个处理过程无二次污染,结果表明该装置及工艺可以用来处理农村生活垃圾,可充分做到垃圾减量化、无害化和资源化.%The environmental risk caused by the rural refuse increasingly is proved to be a big issue because there is not enough place for landfill. A new kind of composting equipment and technology was studied for dealing with such a problem in this paper. The composting equipment, which is composed of 4 bins with 1.56 m3 volume of each bin, was tested for 2 months at the municipal solid waste transfer station at Mengyong village, Panyu district in Guangzhou. The power of exhaust fan was 1.1 kW/h, the operation frequency was 10 times per day, 30 minutes per time, so the total operation time was 5 hours a day, the energy cost of the whole compost was 5.5kW. Through 12 days of high temperature fermentation followed by 24 days of bag fermentation, the temperature could be up to 60 °C for at least 5 days, the volume reduction rate of the rural refuse could reach up to 40% after 12 days, and there was no secondary pollution in the whole compost. The results showed that the composting equipment and technology was a feasible way to realize quantitative reduction, harmlessness and resources recovery of the rural refuse.

  3. Electric utility engineer`s FGD manual -- Volume 2: Major mechanical equipment; FGD proposal evaluations; Use of FGDPRISM in FGD system modification, proposal, evaluation, and design; FGD system case study. Final report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-03-04

    Part 2 of this manual provides the electric utility engineer with detailed technical information on some of the major mechanical equipment used in the FGD system. The objectives of Part 2 are the following: to provide the electric utility engineer with information on equipment that may be unfamiliar to him, including ball mills, vacuum filters, and mist eliminators; and to identify the unique technique considerations imposed by an FGD system on more familiar electric utility equipment such as fans, gas dampers, piping, valves, and pumps. Part 3 provides an overview of the recommended procedures for evaluating proposals received from FGD system vendors. The objectives are to provide procedures for evaluating the technical aspects of proposals, and to provide procedures for determining the total costs of proposals considering both initial capital costs and annual operating and maintenance costs. The primary objective of Part 4 of this manual is to provide the utility engineer who has a special interest in the capabilities of FGDPRISM [Flue Gas Desulfurization PRocess Integration and Simulation Model] with more detailed discussions of its uses, requirements, and limitations. Part 5 is a case study in using this manual in the preparation of a purchase specification and in the evaluation of proposals received from vendors. The objectives are to demonstrate how the information contained in Parts 1 and 2 can be used to improve the technical content of an FGD system purchase specification; to demonstrate how the techniques presented in Part 3 can be used to evaluate proposals received in response to the purchase specification; and to illustrate how the FGDPRISM computer program can be used to establish design parameters for the specification and evaluate vendor designs.

  4. Optimum Design to Hydraulic Pressure System of New Type Pressure Modes of Special Heat Treatment Equipments%专用热处理设备新型施压模式的液压系统优化设计

    Institute of Scientific and Technical Information of China (English)

    张剑慈; 黄云峰; 谢慧萍

    2012-01-01

    一般的淬火设备都是施压与淬火共用一套液压系统,难以满足工作要求,为了保证提高液压淬火系统的工作可靠性,保证产品质量,对表面淬火专用热处理设备的液压系统进行了优化设计.阐述了优化设计后两套独立的液压系统的工作原理,二种施压模式.实践证明:采用该设备对带有中心孔的叶轮、齿轮及盘类零件进行表面淬火,其淬火性能良好.%The generic quenching equipment was usually using a same hydraulic pressure system when pressing and quenching. It was difficult to reach working requirement. In order to make sure to improve the working reliability of hydraulic pressure quenching system, and to assure the quality of the products, the hydraulic pressure system of Special Heat Treatment Equipments with Surface Quenching was designed in optimum. The operating principle and the two sets of pressure modes of the two hydraulic pressure system after optimum designed were expatiated. It has been proved by practice that by adopting this equipment, well performance has been provided with well performance when surface quenching to impellers, gears and disc parts with central holes.

  5. 2007 special equipment safety

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    @@ The General Administration of Quality Supervision, Inspection and Quarantine of P.R.China (AQSIQ) issued a notice on May 28, 2007,requiring various locations to rectify their procedures for checking special equipment and hoisting machines for hidden problems. To further clarify and implement responsibility in the safety management of special equipment in enterprises, inspection responsibilities and test organizations related to technical assurance are to be established. Further, quality inspection departments will be supervised by law in order to improve special equipment safety.

  6. Microfluidic Devices for Manipulation and Detection of Beads and Biomolecules

    OpenAIRE

    Jönsson, Mats

    2006-01-01

    This thesis summarises work towards a Lab-on-Chip (LOC). The request for faster and more efficient chemical and biological analysis is the motivation behind the development of the LOC-concept. Microfluidic devices tend to become increasingly complex in order to include, e.g. sample delivery, manipulation, and detection, in one chip. The urge for smart and simple design of robust and low-cost microdevices is addressed and discussed. Design, fabrication and characterization of such microdevices...

  7. Waste Handling Equipment Devleopment Test and Evaluation

    Energy Technology Data Exchange (ETDEWEB)

    R.L. Tome

    1998-12-01

    The purpose of this study is to identify candidate Monitored Geologic Repository (MGR) surface waste handling equipment for development testing. This study will also identify strategies for performing the development tests. Development testing shall be implemented to support detail design and reduce design risks. Development testing shall be conducted to confirm design concepts, evaluate alternative design concepts, show the availability of needed technology, and provide design documentation. The candidate equipment will be selected from MGR surface waste handling equipment that is the responsibility of the Management and Operating Contractor (M&O) Surface Design Department. The equipment identified in this study is based on Viability Assessment (VA) design. The ''Monitored Geologic Repository Test and Evaluation Plan'' (MGR T&EP), Reference 5.1, was used as a basis for this study. The MGR T&EP reflects the extent of test planning and analysis that can be conducted, given the current status of the MGR requirements and latest VA design information. The MGR T&EP supports the appropriate sections in the license application (LA) in accordance with 10 CFR 60.2 1(c)(14). The MGR T&EP describes the following test activities: site characterization to confirm, by test and analysis, the suitability of the Yucca Mountain site for housing a geologic repository; development testing to investigate and document design concepts to reduce risk; qualification testing to verify equipment compliance with design requirements, specifications, and regulatory requirements; system testing to validate compliance with MGR requirements, which include the receipt, handling, retrieval, and disposal of waste; periodic performance testing to verify preclosure requirements and to demonstrate safe and reliable MGR operation; and performance confirmation modeling, testing, and analysis to verify adherence to postclosure regulatory requirements. Development test activities can be

  8. Design and Implementation of Basic Data Mining System of Secondary Equipment%二次设备基础数据挖掘系统的设计与实现

    Institute of Scientific and Technical Information of China (English)

    林志超

    2016-01-01

    给出面向二次系统辅助决策的供电局二次设备基础数据挖掘系统的技术框架,并从惠州供电局二次设备数据管理的现状及需求出发,设计数据挖掘系统的主要功能模块,主要的数据分析功能包括基础统计及关联规则、聚类分析等数据挖掘方法。最后介绍系统实现。%Presents the technical framework of the secondary equipment data mining system of Power Supply Bureau, which is designed for the deci-sion support of the secondary system in power grid. The main system functional modules are designed based on the analysis of the current situation and requirement of secondary equipment data management in Huizhou Power Supply Bureau. Main data analysis methods in-clude basic statistics, association rules, clustering analysis and other data mining methods. Finally, the implementation of the system is in-troduced.

  9. Implementation of an ex situ stabilization technique at the Sand Springs superfund site to solidify and stabilize acid tar sludges involving a quick-lime based stabilization process and innovative equipment design

    Energy Technology Data Exchange (ETDEWEB)

    McManus, R.W. [SOUND Environmental Services, Inc., Dallas, TX (United States); Grajczak, P. [ARCO, Los Angeles, CA (United States); Wilcoxson, J.C. [ARCO, Plano, TX (United States); Webster, S.D. [Environmental Protection Agency, Dallas, TX (United States)

    1997-12-31

    An old refinery site was safely remediated a year before schedule and for 25% less than final engineering estimates for the stabilization remedy thanks to energetic project management and innovative design involving ex situ stabilization/solidification of acid tar sludges. A quicklime based process, Dispersion by Chemical Reaction (DCR{trademark}), was employed to solidify and stabilize (SS) over 103,000 cubic meters (135,000 cubic yards) of petroleum waste, mostly acidic tarry sludge. The SS process was selected over competing methods because it afforded minimal volume increase, could readily achieve Record of Decision (ROD) specified physical and chemical treatment goals, could be implemented with treatment equipment that minimized emissions, and could be performed with low reagent usage and at low cost. To ensure treatment goals were achieved and an accelerated schedule met, a custom designed and fabricated transportable treatment unit (TTU) was employed to implement the process. The treated material was visually soil-like in character, it was left in stockpiles for periods of time, and it was placed and compacted in the on site landfill using standard earth-moving equipment.

  10. SDH设备时钟中的数字锁相环设计%Design of Digital Phase Locked Loop Used in SDH Equipment Clock

    Institute of Scientific and Technical Information of China (English)

    伍文君; 黄芝平; 章明沛; 刘纯武

    2009-01-01

    A novel Digital Phase Locked Loop used in SDH equipment Clock is proposed. The phase detector of the DPLL is implemented with the time-to-digital converter whose resolution is 200 ps. With this improvement of the phase detector' s resolution, the DPLL shows excellent performance. The DPLL has stable frequency output, has excellent performance to track the reference timing, and can change the reference timing smoothly. It meets the requirement given in ITU-T Recommendation G. 813.%提出了一种新的用于实现SDH设备时钟的数字锁相环,采用时数转换器来实现数字锁相环中的鉴相器;该时数转换器的时间测量精度达到200 ps,因而极大地改进了鉴相器的鉴相精度;改进后的数字锁相环具有很好的频率稳定度和相位特性,对时钟源有很好的跟踪能力,且能实现时钟源的平滑切换.完全满足了ITU-TG.813规范要求.

  11. Dynamics for heavy equipment airdrop and control design%重装空投动力学分析与控制方案研究

    Institute of Scientific and Technical Information of China (English)

    韩艳铧; 陆宇平

    2011-01-01

    A tow-body system of plane-cargo' s dynamics model is built based on the Lagrange analytical mechanics for a heavy equipment airdrop mission. A compensation scheme is proposed to weaken the cargo' s impact to airplane. Numerical simulation shows the dynamic coupling between airplane and cargoes, and the relevancy between the size of extraction parachute and simulation results is analyzed. Numerical simulation results also supports the effectiveness of control law proposed in this paper, that is, flying qualities and safety of airplane are improved significantly.%针对重装空投任务,基于拉格朗日分析力学,建立了货物在机舱内滑行阶段飞机-货物两体系统的动力学模型.给出了一种控制补偿方案,用以抵消或削弱货物运动对飞机的影响.通过数值仿真,观察货物运动和飞机运动之间的耦合关系,分析了牵引伞尺寸对飞机和货物运动参数的影响.仿真结果表明,所给出的控制补偿方案能够有效改善飞机飞行品质,提高飞行安全性.

  12. Division of Scientific Equipment - Overview

    International Nuclear Information System (INIS)

    Full text: The Scientific Equipment Division consists of the Design Group and the Mechanical Workshop. The activity of the Division includes the following: * designs of devices and equipment for experiments in physics; their mechanical construction and assembly. In particular, these are vacuum chambers and installations for HV and UHV;* maintenance and upgrading of the existing installations and equipment in our Institute; * participation of our engineers and technicians in design works, equipment assembly and maintenance for experiments in foreign laboratories. The Design Group is equipped with PC-computers and AutoCAD graphic software (release 2000 and Mechanical Desktop 4.0) and an A0 plotter, which allow us to make drawings and 2- and 3-dimensional mechanical documentation to the world standards. The Mechanical Workshop offers a wide range of machining and treatment methods with satisfactory tolerances and surface quality. They include: * turning - cylindrical elements of a length up to 2000 mm and a diameter up to 400 mm, and also disc type elements of a diameter up to 600 mm and a length not exceeding 300 mm, * milling - elements of length up to 1000 mm and gear wheels of diameter up to 300 mm, * grinding - flat surfaces of dimensions up to 300 mm x 1000 mm and cylindrical elements of a diameter up to 200 mm and a length up to 800 mm, * drilling - holes of a diameter up to 50 mm, * welding - electrical and gas welding, including TIG vacuum-tight welding, * soft and hard soldering, * mechanical works including precision engineering, * plastics treatment - machining and polishing using diamond milling, modelling, lamination of various shapes and materials, including plexiglas, scintillators and light-guides, * painting - paint spraying with possibility of using furnace-fired drier of internal dimensions of 800 mm x 800 mm x 800 mm. Our workshop is equipped with the CNC milling machine which can be used for machining of work pieces up to 500 kg. The machine

  13. A Design Method of Hydraulic System of Rolling Equipments Based on Excel%基于Excel表的轧钢设备液压系统设计方法

    Institute of Scientific and Technical Information of China (English)

    2013-01-01

    A method based on Excel is proposed, which is designed for hydraulic system of rolling equipments as well as rolling line. The system flow, valve normal size and steel pipe line can be calculated automatically and easi-ly, which makes design simple, efficient and standard, and cuts the cost of production.%  针对轧钢设备和轧钢生产线的液压系统设计,提出了一种基于Excel表的设计方法,实现系统流量自动计算、液压阀通径和金属管路自动选择,从而简化设计流程,提高设计效率。

  14. 小型真空双锅油炸设备控制系统的设计%Designing the Control System of the Small Double-Cauldron Vacuum Frying Equipment

    Institute of Scientific and Technical Information of China (English)

    夏德昭; 刘铎; 向立志

    2001-01-01

    提出了以单片机为核心、PC机作监控的小型真空双锅油炸设备控制系统,详细介绍了软硬件的具体设计过程。新型芯片和典型抗干扰措施的使用提高了控制的性能,增强了系统的稳定性。%Using the single chip processor as the center and a IBM-PC computer as the monitor, we design this control system of the small double-cauldron vacuum frying equipment. The process of software and hardware designing is described in this paper in detail. The application of the new elements and the typical measures of resisting interference improves the control performance and enhances the reliability of control system.

  15. Manufacture of Automatic Heating Equipment for AES

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    This paper introduced the design and application of automaticheating equipment for Auger Emission Spectroscopy (AES). The special electric furnace used in the AES was designed, the Al2O3 glass window which allows both visible light and infrared ray to pass through was made, and the MA2S/B thermo-meter based on infrared ray radiant energy from the sample was selected. The equipment gives dynamic analyzingby AES. It offers possibilities for widening the fields of materials surface and interface research . As a sample , the FeCr17 alloy was studied by in situ AES in the heating progress with the help of automaticheating equipment.

  16. Cellular Viscosity in Prokaryotes and Thermal Stability of Low Molecular Weight Biomolecules.

    Science.gov (United States)

    Cuecas, Alba; Cruces, Jorge; Galisteo-López, Juan F; Peng, Xiaojun; Gonzalez, Juan M

    2016-08-23

    Some low molecular weight biomolecules, i.e., NAD(P)H, are unstable at high temperatures. The use of these biomolecules by thermophilic microorganisms has been scarcely analyzed. Herein, NADH stability has been studied at different temperatures and viscosities. NADH decay increased at increasing temperatures. At increasing viscosities, NADH decay rates decreased. Thus, maintaining relatively high cellular viscosity in cells could result in increased stability of low molecular weight biomolecules (i.e., NADH) at high temperatures, unlike what was previously deduced from studies in diluted water solutions. Cellular viscosity was determined using a fluorescent molecular rotor in various prokaryotes covering the range from 10 to 100°C. Some mesophiles showed the capability of changing cellular viscosity depending on growth temperature. Thermophiles and extreme thermophiles presented a relatively high cellular viscosity, suggesting this strategy as a reasonable mechanism to thrive under these high temperatures. Results substantiate the capability of thermophiles and extreme thermophiles (growth range 50-80°C) to stabilize and use generally considered unstable, universal low molecular weight biomolecules. In addition, this study represents a first report, to our knowledge, on cellular viscosity measurements in prokaryotes and it shows the dependency of prokaryotic cellular viscosity on species and growth temperature. PMID:27558730

  17. Extraction of Biomolecules Using Phosphonium-Based Ionic Liquids + K3PO4 Aqueous Biphasic Systems

    Directory of Open Access Journals (Sweden)

    Cláudia L. S. Louros

    2010-04-01

    Full Text Available Aqueous biphasic systems (ABS provide an alternative and efficient approach for the extraction, recovery and purification of biomolecules through their partitioning between two liquid aqueous phases. In this work, the ability of hydrophilic phosphonium-based ionic liquids (ILs to form ABS with aqueous K3PO4 solutions was evaluated for the first time. Ternary phase diagrams, and respective tie-lines and tie-lines length, formed by distinct phosphonium-based ILs, water, and K3PO4 at 298 K, were measured and are reported. The studied phosphonium-based ILs have shown to be more effective in promoting ABS compared to the imidazolium-based counterparts with similar anions. Moreover, the extractive capability of such systems was assessed for distinct biomolecules (including amino acids, food colourants and alkaloids. Densities and viscosities of both aqueous phases, at the mass fraction compositions used for the biomolecules extraction, were also determined. The evaluated IL-based ABS have been shown to be prospective extraction media, particularly for hydrophobic biomolecules, with several advantages over conventional polymer-inorganic salt ABS.

  18. Applications of Oblique-Incidence Reflectivity Difference Method in Primary Study of Protein Biomolecules

    Institute of Scientific and Technical Information of China (English)

    ZHANG Hong-Yan; LIANG Ru-Qiang; JIN Kui-Juan; L(U) Hui-Bin; ZHU Xiang-Dong; ZHOU Yue-Liang; RUAN Kang-Cheng; YANG Guo-Zhen

    2006-01-01

    @@ Oblique-incidence reftectivity difference (OI-RD) analysis is applied to detect the immunoglobulin-G and cytochrome biomolecules on standard glass substrates without fluorescence labelling. The OI-RD intensities not only depend on the protein structure, but also vary with the protein concentration. The results indicate that this method should have potential applications in detection of biochemical processes.

  19. Photonic crystal fiber based evanescent-wave sensor for detection of biomolecules in aqueous solutions

    DEFF Research Database (Denmark)

    Jensen, Jesper Bo Damm; Pedersen, Lars H.; Hoiby, Poul E.;

    2004-01-01

    We demonstrate highly efficient evanescent-wave detection of fluorophore-labeled biomolecules in aqueous solutions positioned in the air holes of the microstructured part of a photonic crystal fiber. The air-suspended silica structures located between three neighboring air holes in the cladding...

  20. The Design and Actualization of the Electromagnetic Emission Evaluation Software for the Electronic Equipment at the Radio Astronomy Station%电子设备电磁辐射评估软件设计及实现

    Institute of Scientific and Technical Information of China (English)

    李颖; 刘奇; 刘艳玲; 孙正文; 陈卯蒸; 张群涛

    2016-01-01

    Because of numerous instruments and equipment existing in the radio telescope system and observatory site, the electromagnetic environment becomes complicated and astronomical observations become difficult. Radio telescopes are extremely sensitive systems, and electromagnetic emission from electronic equipment in their neighborhood must be tightly controlled. The Electro-Magnetic Compatibility ( EMC ) is concerned with the design and operation of equipment in such a way:they are immune to the Electro-Magnetic Interference ( EMI) while at the same time they do not interfere with other equipment in the same environment. The electromagnetic compatibility design, shielding design and emission assessments are all dependent on the data processing and analysis. Therefore the routinization is the only way to improve the test efficiency and the data analysis. Firstly, the measurement system, the evaluation process, goals and the key technic problems of the software design are analyzed in this paper. Based on the data transfer properties, processing and data storage in the software, the flow chart, data flow diagram and the key interpolation algorithm flow chart of the evaluation software are given. The main data characteristics and the date storage methods of the evaluation processing are also analyzed, then the data storage and management module based on the data source and the database is developed. Secondly, based on the Microsoft Visual Studio 2010 development platform, the electromagnetic radiation evaluation software is developed through lots of program debugging and optimization, which is capable for the rapid test, the analysis and the evaluation of the equipment radiation characteristics, which provides an important reference for the electromagnetic compatibility designing for the radio astronomy observatory. Meanwhile, with the software used, the repeated and tedious testing process and the data process also become easy, greatly improving the data reliability and

  1. Design and analysis of sodium carbonate recycling drying equipment for cyclohexanone production%环己酮生产中碳酸钠回收干燥装置的设计与分析

    Institute of Scientific and Technical Information of China (English)

    黎树根

    2012-01-01

    A new type of drying equipment was designed according to the characteristics of the recycling and utilization of waste sodium carbonate as the by-product of alkali waste burning in cyclohexanone process. The drying process, structure and working principle of the drying equipment were analyzed and calculated. The results showed that the automatic recycling drying equipment for sodium carbonate was consist of drying box, heating air system, dehumidifying system, scattering system and packaging system. The drying curves of sodium carbonate drying equipment were obtained through the drying experiment using a temperature-control electric oven. The drying capacity of this system reached 1 -2 t/h and the moisture content of sodium carbonate was below 2% after drying. The system saved the drying cost without environment pollution by using process gas waste as the heat re-souce. This equipment had the advantages of high drying capacity, high thermal efficiency, low energy consumption and good regulation performance, which successfully resolved the problem of alkali waste treatment in cyclohexanone industry.%针对环己酮生产过程中废碱碳酸钠回收利用的工艺特点,设计了一种新型干燥装置,对干燥器的干燥流程、干燥器的结构和工作原理进行了分析及计算.结果表明:循环自动干燥碳酸钠设备主要由干燥箱、供热风系统、抽湿系统、扩散系统和包装系统组成;通过温控由电烘箱进行碳酸钠干燥实验,得到了碳酸钠干燥设备的干燥曲线,该系统干燥能力达1 ~2 t/h,干燥后碳酸钠含水率小于2%;该系统利用工厂废烟气作热源,节省干燥成本,且无环境污染.该设备干燥能力大,热效率高,能耗低,调控性能好,很好的解决了环己酮工业中废碱处理的难题.

  2. 考虑不确定性的保障设备设计方案决策方法%A Decision-making Method about Design Proposal of Support Equipment Taking Uncertainty into Account

    Institute of Scientific and Technical Information of China (English)

    李华府

    2011-01-01

    The author researched into the influence of fuzziness on the optimum decision-making process of support equipment design proposal,proposed a comprehensive decision-making method based on fuzzy mathematics theory and grey correlation analysis. Taking uncertainty into account,and established a mathematical model. This model determines the relative superior grey correlation degress of every tradeoff design proposal through calculation of fuzzy grey correlation coefficients of every support equipment tradeoff design scheme, and sequences the tradeoff design proposals according to the good and the bad in accordance with grey correlation degree for realizing decision-making.%研究了模糊性对装备的保障设备设计方案优选决策过程中的影响,基于模糊数学理论和灰色关联分析提出了一个考虑不确定性的综合决策方法,并建立了数学模型.该模型通过计算各保障设备的备选设计方案到正、负理想设计方案的模糊灰色关联系数,来确定各备选方案的相对优势灰色关联度,依据相对灰色关联度对各备选方案进行优劣排序,实现决策.通过某型机载装备的外场测试设备方案的立项竞标决策案例,对模型进行了应用.

  3. Lightweight Design of Special Emergency Lifting Device of a Special Equipment%特种装备专用应急起重装置轻量化设计

    Institute of Scientific and Technical Information of China (English)

    郑艳琴; 向敢; 刘建华; 柯争华; 方利卡; 翁泽宇

    2012-01-01

    In according to the needs of use, maintenance and repair of a special equipment, and make clear the basic requirements of design of special emergency lifting device of a special equipment, the paper introduced the overall plan of design of this special emergency lifting device. Proceeded to finite element analysis on this lifting device with software ANSYS and checked the intensity of overall structure. Introduced a concept of lightweight design and carried on structure optimization on overall structure of this special emergency lifting device and focused on weight reduction on side plate of girder. The finite element analysis results show that the new design of overall structure of the emergency lifting device can meet the required intensity and at the same time the whole weight can reduce from 220 kg to 181 kg compare with the original project. [ Ch,6 fig. 11 ref. ]%根据某特种装备使用、维护和维修的需要,明确该设备专用应急起重装置的设计基本要求,确定总体方案设计.利用有限元软件ANSYS对该起重装置整体结构进行有限元分析,验算整体结构的强度.引入轻量化设计理念,对该专用应急起重装置整体结构进行结构优化,大粱侧板进行了重点的减重处理.有限元分析结果表明,新设计的应急起重装置总体结构在满足强度要求的同时,整体重量从原结构方案的220 kg减轻到181 kg.

  4. 智能脊柱理疗设备摆动机构设计与分析%Design and analysis of swingi ng mechanism of the intelligent spine physiotherapy equipment

    Institute of Scientific and Technical Information of China (English)

    张凯; 何非; 李东波

    2015-01-01

    In order to design the swinging mechanism that meets the functional requirements of the intelligent spine physiotherapy equipment , it compares the structural characteristics of several typical swinging mechanism , designs the mechanism for ensuring the realization of the function .Based on SolidWorks it establishes the whole 3D model,designs that the maximum swing speed is 100 times/min, the maximum load of the intelligent spine physiotherapy equipment is 100 kg.A dynamics simulation is performed with ADAMS to simulate the actual mo-tion of the motor , provides reasonable reference for motor selection .A dynamic analysis of the key shaft is per-formed with the finite element software ABAQUS for the optimization design of the shaft .The result shows that the swinging mechanism meets the functional requirements .%为设计满足智能脊柱理疗设备功能要求的摆动机构,对比了多种典型的摆动机构特点,设计了主体机构,同时为确保功能实现设计了辅助机构,并在SolidWorks 中构建了整体三维模型.设计最大摆动速度为100次/min,智能脊柱理疗设备最大承重为100kg. 通过ADAMS动力学仿真模拟其真实环境下的运动情况,对电机合理选型;利用ABAQUS对摆动机构关键零件支撑轴进行显式动态分析,优化设计支撑轴. 仿真与分析结果表明,摆动机构满足功能要求.

  5. Minimum Weight Design of a Leaf Spring Tapered in Thickness and Width for the Hubble Space Telescope-Space Support Equipment

    Science.gov (United States)

    Rodriguez, P. I.

    1990-01-01

    A linear elastic solution to the problem of minimum weight design of cantilever beams with variable width and depth is presented. The solution shown is for the specific application of the Hubble Space Telescope maintenance mission hardware. During these maintenance missions, delicate instruments must be isolated from the potentially damaging vibration environment of the space shuttle cargo bay during the ascent and descent phases. The leaf springs are designed to maintain the isolation system natural frequency at a level where load transmission to the instruments in a minimum. Nonlinear programming is used for the optimization process. The weight of the beams is the objective function with the deflection and allowable bending stress as the constraint equations. The design variables are the width and depth of the beams at both the free and the fixed ends.

  6. 某型雷达自动测试设备的设计%Design of Automatic Test Equipment for Certain Guidance Radar

    Institute of Scientific and Technical Information of China (English)

    马艳

    2012-01-01

    捷变频雷达具有频率快速跳变、不易被捕获而受到干扰的特点,以往对捷变频雷达的测试采用静态分析方法,不能反映雷达真实的工作状态;文章基于PXI总线构建新型捷变频雷达测试设备,通过研制一种能覆盖捷变频雷达的频率范围并自动跳频的信号源,实现了测试设备跟随雷达频率自动跳频进行雷达的自动测试,能真实反映雷达的工作状态;实验结果表明,系统检测与控制精度高,具有一定的实用性.%Frequency agility radar is a kind of guidance radar system, which has the characteristics of quick frequency agility and difficult being captured and disturbed. The traditional test of frequency agility radar is performed by static analysis method. It cannot give the true operation state of radar. A new test equipment is proposed in this paper based on PXI bus. By the simulator of signal source developed, which can cover the frequency coverage of frequency agility radar and hop frequency automatically, the radar can be automatic agility frequency tested by simulator following radar frequency. Based on the new simulator, the true operation of radar is given. The experimental results show that the automatic test system has high accuracy. The technology and methods adopted in the system are practical.

  7. Improvement of the obtention process of 131 I of ININ through studies of equipment design and process parameters fitting in the simulator

    International Nuclear Information System (INIS)

    The main objective of the work was to achieve a high yield of the reaction that happens among the vapors of 131 I and the NaOH to obtain sodium iodide (Na131 I) in solution optimizing the contact time of the molecules in gaseous state of 131 I with the NaOH molecules through the bubbling velocity of the 131 I in the solution of NaOH 0.1 N, as well as the operation temperature during the distillation process by dry via starting from tellurium dioxide (TeO2) with the purpose of that the 131 I that is obtained in the form of Na131 I solution presents the necessary quality that allows to distribute it in the market. The particular objectives were: a) To improve the distillation equipment used for the obtaining of 131 I starting from irradiated tellurium dioxide redrawing the dilution system with the purpose of recovering the 131 I in a minimum volume of sodium hydroxide (NaOH). b) To achieve a bigger time of contact among the molecules of 131 I in gaseous state with the molecules of NaOH in solution through the bubbling velocity and of the redrawing of the dilution system. c) To implement the production of 131 I by dry distillation via starting from tellurium dioxide, obtaining it with a high radionuclide and radiochemical purity. d) To obtain 131 I with the necessary specifications that it marks the pharmacopoeia and it can be used with medical ends. (Author)

  8. The application of a self-design electric leakage detector in detecting laparoscopic equipment%一种自设计漏电检测仪在杆状腔镜器械漏电检测中的应用

    Institute of Scientific and Technical Information of China (English)

    胡玉琴; 刘红松; 黄天翊; 陈肖敏

    2016-01-01

    目的:设计一种检测腔镜杆状器械漏电的装置,以有效解决因腔镜器械漏电造成的脏器副损伤问题。方法:在专利技术的基础上设计漏电检测仪,实现杆状腔镜手术器械漏电检测与漏电点精确检测,并对2013-2015年期间医院手术腔镜器械进行检测验证。结果:应用漏电检测仪检测6500余件腔镜器械,检测出1138件绝缘层破裂漏电器械,检出率为17.5%,有效降低了腔镜手术器械漏电原因造成的脏器副损伤的发生。结论:新型杆状腔镜器械漏电检测仪具有有效性和实用性,为手术以及器械安全管理与维护提供了检测器具,具有技术推广价值,可为建立腔镜器械使用追溯系统、实现腔镜器械闭环管理打下基础。%Objective:To design a device for detecting laparoscopic equipment electric leakage is to prevent the secondary viscera injury from electric leakage of laparoscopic equipment. Methods: On the basis of patent technology, the new detector was designed to detect the electric leakage of laparoscopic instrument accurately for leakage detection and leakage point of rod-shaped endoscopic devices. And surgical endoscopic equipments were tested by the new detector in the hospital between 2013 and 2015.Results: We tested over 6500 pieces of laparoscopic instruments by the electric leakage detector and found 1138 pieces of laparoscopic instruments due to insulation cracking. The detection rate was 17.5%. This new device could reduce the electric leakage of surgical laparoscopic instruments to avoided secondary viscera injury significantly.Conclusion: It is effective and practical for operation and safety management and maintenance of surgical laparoscopic instruments. This device could set up the base for establishment of tracing system of endoscopic instrument to achieve closed-loop management of endoscopic equipment. It’s worth to being popularized.

  9. Design of Remote Monitoring and Diagnosis System of Conveying Equipments on Working Face Based on LabVIEW%基于LabVIEW的工作面输送设备远程监测与诊断系统设计

    Institute of Scientific and Technical Information of China (English)

    雷志鹏; 宋建成; 李艳伟; 崔晓慧

    2012-01-01

    In view of problem that current monitoring and diagnosis systems of conveying equipments on working face can be only used at underground field, a remote monitoring and diagnosis system of conveying equipments based on LabVIEW in surface dispatching center was designed. General structure of monitoring and diagnosis system of conveying equipments of whole mine manless working face composed of the system and underground monitoring and fault diagnosis system of conveying equipments based on PLC was given, implementation of data exchange between the system and the underground system was analyzed, and method of BP neural network fault identification in LabVIEW and design of SQL Server data management system were introduced. The actual application shows that the system runs stably and realizes real-time monitoring and diagnosis of conditions of scraper conveyor, transfer conveyor and crusher on working face in surface dispatching center.%针对现有工作面输送设备监测与诊断系统只能在井下现场使用的问题,设计了一种基于LabVIEW的安装于地面调度中心的输送设备远程监测与诊断系统;给出了由该系统与井下基于PLC的输送设备监测与诊断系统相结合构成的全矿井无人工作面输送设备监测与诊断系统的整体结构,分析了该系统与井下系统间的数据交换实现,介绍了在LabVIEW中运行BP神经网络故障识别的方法及SQL Server数据管理系统的设计.实际应用表明,该系统运行稳定,实现了在地面调度中心实时监测和综合诊断工作面刮板输送机、转载机和破碎机的工况.

  10. 民用飞机设计驾驶舱操纵设备的评估%Evaluation on Flight Cockpit Control Equipments of Civil Aircraft Design

    Institute of Scientific and Technical Information of China (English)

    丰立东; 赵京洲; 田金强

    2013-01-01

    人机工效影响着飞行员操纵飞机的感受,因此在民用飞机设计过程中,对人机工效进行及早考虑是非常重要的。在民用飞机设计的各个阶段,都需要适时邀请具有一定资质的飞行员对驾驶舱的人机工效进行评估。对民用飞机设计中飞控驾驶舱飞行员评估方法进行介绍,对评估的要点进行总结分析,供相关工程设计人员参考。%Human factors affect the feeling of pilots operating airplanes. It is necessary to take human factors into account at the beginning of designing civil aircraft. During each phase of designing civil aircraft, it is necessary to invite qualified pilots to evaluate human factors in cockpit when needed. A method of pilot evaluation related with flight cockpit control system in designing civil airplane is introduced and some important issues are summarized and analyzed so as to refer to other relevant engineers and designers when necessary.

  11. Equipment maintenance and repair

    Directory of Open Access Journals (Sweden)

    Walia DS

    2010-10-01

    Full Text Available The repair and maintenance of ophthalmic equipment, including surgical instruments and diagnostic devices, can be compared to the maintenance of a motor vehicle, something many of us understand well.If you had a car, would you drive it until the fuel runs out or until a tyre punctures, and then abandon it to buy a new car? Of course not. However, many eye care units purchase (or receive as a donation expensive and delicate equipment which, because of poor maintenance, ends up breaking down. If there is not a system in place to report breakdowns and to plan or carry out repairs, equipment can remain unusable for long periods of time. Sometimes, this equipment ends up being dumped. Good maintenance habits and an effective repair system will minimise the amount of time equipment is unusable.

  12. PROMSYS, Plant Equipment Maintenance and Inspection Scheduling

    International Nuclear Information System (INIS)

    1 - Description of problem or function: PROMSYS is a computer system designed to automate the scheduling of routine maintenance and inspection of plant equipment. This 'programmed maintenance' provides the detailed planning and accomplishment of lubrication, inspection, and similar repetitive maintenance activities which can be scheduled at specified predetermined intervals throughout the year. The equipment items included are the typical pumps, blowers, motors, compressors, automotive equipment, refrigeration units, filtering systems, machine shop equipment, cranes, elevators, motor-generator sets, and electrical switchgear found throughout industry, as well as cell ventilation, shielding, containment, and material handling equipment unique to nuclear research and development facilities. Four related programs are used to produce sorted schedule lists, delinquent work lists, and optional master lists. Five additional programs are used to create and maintain records of all scheduled and unscheduled maintenance history. 2 - Method of solution: Service specifications and frequency are established and stored. The computer program reviews schedules weekly and prints, on schedule cards, instructions for service that is due the following week. The basic output from the computer program comes in two forms: programmed-maintenance schedule cards and programmed-maintenance data sheets. The data sheets can be issued in numerical building, route, and location number sequence as equipment lists, grouped for work assigned to a particular foreman as the foreman's equipment list, or grouped by work charged to a particular work order as the work-order list. Data sheets grouped by equipment classification are called the equipment classification list

  13. 应用于射电天文数字终端的网络传输系统的设计%The Design of Network Transmission System Applied in Radio Astronomy Digital Equipment

    Institute of Scientific and Technical Information of China (English)

    于威; 张秀忠; 吴亚军; 郭绍光; 甘江英

    2012-01-01

    射电天文数字终端对各类天体发出的无线电信号进行处理后,需把数据传送到数据记录设备存储起来,以进行更进一步的分析和处理.为了满足数据传输需要,本文设计了一种千兆网网络传输系统把射电天文数字终端产生的数据传送到数据记录设备,测试结果表明,该网络系统在数据速率低于640 Mb/s的情况下工作良好,数据丢失率非常低.目前该系统己初步应用于DBBC、连续谱终端等射电天数字终端中.%When radio signal was processed by radio astronomy digital equipment, we need to transmit it to data record equipment, so that we can undertake further analysis and processing. In order to satisfy the requirement of data transmission, in this paper we designed a network transmission system based on Gigabit Ethernet. The test result showed that this system worked well when the data rate was lower than 640 Mb/s. Now this system has been applied in some radio astronomy equipments such as DBBC, continuous spectrum instrument and so on.

  14. 变速箱装配线设备管理信息系统设计与实现%Gearbox Assembly Line Equipment Management Information System Design and Implementation

    Institute of Scientific and Technical Information of China (English)

    贾亮; 王雅君; 王德权

    2014-01-01

    该文是通过对南昌某双离合器变速箱装配企业的管理制度和业务流程的分析和研究,设计了一套设备管理信息系统,该系统是以OPC、UDP远程通讯技术为基础,通过计算机和PLC的信息交互,实现了对变速箱装配线各个工位的设备工作状态进行实时监控,显示现场装配设备的故障报警信息、维护保养信息等。同时采集并存储装配过程中的重要数据,为后续的SPC、OEE分析提供了依据。该系统已在装配现场应用,并满足了生产要求。%This article is based on the Nanchang some double clutch transmission assembly enterprise management system and business process analysis and research, design a set of equipment management information system, this system is based on OPC, UDP remote communication technology, through the information interaction of computer and PLC, realized the transmission as-sembly line every station equipment working status real-time monitoring, display field assembly equipment malfunction alarm in-formation, maintenance, etc. Acquisition and store the important data in the assembly process at the same time , and provide the basis for the follow-up of SPC, OEE analysis. The system has been applied to assembly on site, and meet the production require-ments.

  15. Design of Repairable EMI/Moisture Sealing Techniques for Electronic Equipment%电子设备可维修电磁干扰/水汽密封技术设计

    Institute of Scientific and Technical Information of China (English)

    谢义水

    2011-01-01

    在实际环境下,由导电衬垫实现电磁屏蔽的电子设备,因电化学腐蚀频仍发生,因而环境适应性差,是亟待解决的工程技术难题。文中以材料腐蚀学和防护工程学为基础,应用既能实现水汽密封,又能对电磁泄漏发射能量起衰减作用的"密封屏蔽衬垫"实现电子设备可维修水汽密封与电磁屏蔽复合防护设计,满足了电子设备抗恶劣气候环境和电磁环境的防护性、可靠性、维修性、实装性和低成本等综合技战术要求。%In the realistic environment,the frequent occurrence of electrochemical corrosion in electronic equip-ment due to the use of conductive gaskets has led to the poor environmental adaptability,which is an urgent problem to solve.On the basis of the theory of the material corrosion and protection engineering,the application of seal-shield gasket in electronic equipment can seal moisture and reduce the emission energy of electromagnetic leakage.Thus the compound repairable protection design of moisture sealing and electromagnetic shielding can be achieved.And its advantages can meet the requirements of technology and tactics in adverse climate and electromagnetic environment such as protection,reliability,maintenance,economics,practicability etc.

  16. 5kt/a液体二氧化硫装置的工艺设计与设备选型%Process design and equipment selection of 5 kt/a liquid sulphur dioxide plant

    Institute of Scientific and Technical Information of China (English)

    伊允金

    2011-01-01

    介绍了5 kt/a液体二氧化硫装置工艺设计和设备选型情况。该装置采用柠檬酸钠法工艺,工艺参数选择合理、设备选型得当,目前已稳定运行1年多时间,各项工艺指标均达到或超过设计值。实际消耗硫磺0.45 t/t、电110kWh/t、柠檬酸10kg/t、纯碱18kg/t、0.3~0.4 MPa蒸汽0.4 t/t。探讨了设计生产中几个需要注意的问题,如输送管道材质选择、SO3吸收塔进口气温控制、柠檬酸钠溶液浓度控制、吸收尾气处理等。%Process design and equipment selection of a 5 kt/a liquid sulphur dioxide plant are described,which uses sodium citrate process with reasonable process parameters and equipment and materials.The plant has operated for more than one year and every operation index reached or was superior to design value.Actual operation showed that the consumption of sulphur was 0.45 t/t,power 110 kWh/t,citric acid 10 kg/t,soda ash 18 kg/t and 0.3-0.4 MPa steam 0.4 t/t.Several issues that need attention in design and production are discussed,such as selection of pipeline material,control of inlet gas temperature of SO,absorption tower and sodium citrate concentration, and tail gas treatment.

  17. 基于Zigbee的低压设备能耗与谐波监测节点设计%The Node Design of Energy Cost and Harmonic Monitoring for Low-Voltage Equipment based on Zigbee

    Institute of Scientific and Technical Information of China (English)

    吴迪迪; 窦文雷; 王海鳌

    2012-01-01

    为了对智能楼宇内用电设备所产生的功耗及谐波污染情况进行监测,进而为智能楼宇降低功耗、提高用电效率提供参数依据.设计了基于Zigbee无线网络的功耗与谐波监测节点。该节点由电力监测模块和Zigbee网络模块组成,二者分别实现信号的检测和传输功能,共同构成一个完整的监测节点。主要介绍Zigbee网络的构建和电力监测方法,设计基于三星$3C2410嵌入式处理器的谐波与功耗监测模块,论述Zigbee网络模块的软硬件设计并建立星型网络连接。经试验检测,设备可监控和累计用电设备的电能损耗及谐波污染情况,并通过Zigbee无线网络将数据发送至上位机。%In order to detect the power and harmonic pollution of the intelligent buildings, thereby reducing power consumption for smart buildings and improve the efficiency of electricity parameters in accordance with, the power consumption and harmonic monitoring node based on Zigbee wireless has been designed in this paper. The equipment include a power monitoring part and a Zigbee wireless network part which two complete power monitoring function together. This paper focuses on the Zigbec network and power monitoring methods; designed power monitoring module based on Samsung S3C2410 embedded processor; Zigbee terminal nodes, touters, and the coordination of hardware and software design are discussed in detail and establish a star network connection. Detected by the test, the device can monitor and accumulated electrical energy consumption, it can monitor and cumulative the energy loss and harmonic pollution which generated by the electrical equipment. The data will send to the host computer by Zigbee wireless network. The manner of equipment organization's network is simple and flexible, the device are easy to use and enable to complete the monitoring function.

  18. Unique safety valve design using a floating magnetic coupler and metal-to-metal sealing capability reduces pressure equipment requirements and increases safety valve integrity in ultra deepwater applications

    Energy Technology Data Exchange (ETDEWEB)

    Vinzant, Mike; Vick, James [Halliburton Energy Services, Inc. (United States); Parakka, Anthony [Dexter Magnetic Technology, Inc., Elk Grove Village, IL (United States)

    2004-07-01

    Simplified design concepts, increased use of non-elastomeric and metal-to-metal (M-t-M) sealing materials, and enhanced validation testing have drastically improved tubing-retrievable safety valve (TRSV) performance over the last decade. However, the demands imposed by deep-water, high-pressure/high-temperature (HP/HT) environments, high-flow-rate gas reservoirs and remote subsea applications have also increased, and in spite of continuing improvement in safety-valve technology, equipment has continued to be pushed to its limits. This paper reviews the challenges in achieving 100% M-t-M sealing capability within a TRSV. In addition, this paper will review a unique TRSV design that is a revolutionary new concept. This design incorporates a floating magnetic coupler that allows the hydraulic actuator to be positioned in a dedicated chamber isolated from contact with well fluids and pressure. Since the hydraulic actuator has been separated from the tubing wellbore, this new valve is the first in the industry to have 100% M-t-M sealing with no moving seals within the tubing wellbore. The magnetic-coupler concept particularly benefits deep and ultra deep completions as the TRSV is set deeper, and thus, requires additional operating pressure. By using the magnetic coupler design, the operating pressure required for the TRSV is drastically reduced by removing any interaction between the hydraulic operating piston and the internal tubing-wellbore pressure. This is significantly beneficial for deep water systems where a lower operating pressure simplifies the overall operating system. This is important both for safety and costs since the use of the magnetic coupler design in subsea systems could eliminate the need for high-pressure equipment and the associated high-pressure umbilicals, far outweighing the cost of the TRSV. Some of the benefits of this new intrinsically simple design include: 1. Increases environmental and personnel safety; 2. Reduces system costs; 3

  19. 太阳能干燥热带牧草设备设计研究%Solar Drying of Tropical Forage Equipment Design

    Institute of Scientific and Technical Information of China (English)

    王娟

    2014-01-01

    热带牧草的干燥品质关系着热带畜牧业的发展。由于海南岛太阳辐射强度大,因而设计了用于太阳能干燥热带牧草的平台,其主要由太阳能集热器、风机、干燥仓、风道和控制系统等组成。针对干燥平台设计优化了太阳能集热器,对其结构、吸热涂层材料、上下通道距离比值、串并联连接方式等对集热效率的影响进行实验研究,并设计一套自动跟踪太阳能集热器系统,最终确定优化的实验平台。太阳能干燥热带牧草成本低、环保、效率高,具有广阔的市场前景。%Tropical forage dry relation with tropical development of animal husbandry , Hainan island has strong solar ra-diation , design a solar drying tropical forage platform , the test platform consists of solar collectors , fans, dry warehouse , duct , control systems and other components .Design and optimization a drying platform for flat-plate solar collectors , do-ing experimental study on collector efficiency which impact by Its structure , absorbing coating material , the upper and lower channel distance ratio , series and parallel connections , etc.And to design a set of automatic tracking solar collector system ,ultimately determine the optimal test platform .Solar drying of tropical forages has low cost , green, high efficien-cy , and has broad market prospects .

  20. Solar Drying of Tropical Forage Equipment Design%太阳能干燥热带牧草设备设计研究

    Institute of Scientific and Technical Information of China (English)

    王娟

    2014-01-01

    热带牧草的干燥品质关系着热带畜牧业的发展。由于海南岛太阳辐射强度大,因而设计了用于太阳能干燥热带牧草的平台,其主要由太阳能集热器、风机、干燥仓、风道和控制系统等组成。针对干燥平台设计优化了太阳能集热器,对其结构、吸热涂层材料、上下通道距离比值、串并联连接方式等对集热效率的影响进行实验研究,并设计一套自动跟踪太阳能集热器系统,最终确定优化的实验平台。太阳能干燥热带牧草成本低、环保、效率高,具有广阔的市场前景。%Tropical forage dry relation with tropical development of animal husbandry , Hainan island has strong solar ra-diation , design a solar drying tropical forage platform , the test platform consists of solar collectors , fans, dry warehouse , duct , control systems and other components .Design and optimization a drying platform for flat-plate solar collectors , do-ing experimental study on collector efficiency which impact by Its structure , absorbing coating material , the upper and lower channel distance ratio , series and parallel connections , etc.And to design a set of automatic tracking solar collector system ,ultimately determine the optimal test platform .Solar drying of tropical forages has low cost , green, high efficien-cy , and has broad market prospects .

  1. Atlas风机防喘振辅助设计及应用%Design and Application of Surge-Proof for Atlas Fan Auxiliary Equipment

    Institute of Scientific and Technical Information of China (English)

    崔银峰

    2012-01-01

    This paper mainly introduces the Atlas fan control circuit and analyzes the surging causes of fan. The design schemes optimizes surge-proof control and implementation for Ausmelt blowing technology on Atlas air blower.%本文主要介绍了Atlas风机的控制回路,并对风机喘振原因进行了分析.阐述了Ausmelt吹炼工艺中Atlas风机的防喘振优化设计方案与实施.

  2. Distribution Design for Kitchen Garbage Treatment Equipment of Wudang District in Guiyang%贵阳市乌当区厨余垃圾处理设备的分布设计

    Institute of Scientific and Technical Information of China (English)

    何春银; 王德盛; 吴晗; 廖玉梅

    2012-01-01

    随着城市化步伐的加快,生活垃圾量在不断地增加,传统的填埋方式不再适应社会的发展,今后的生活垃圾应进行科学的处理,变废为宝,再创价值。通过建立平面直角坐标系确定乌当区各镇的位置,且假设乌当区的厨余垃圾以镇为中心进行收集和运输,运用最小二乘法和MATLAB软件,求出设备的量和安置的最佳坐标。%As the pace of urbanization speed up, life garbage in continuing to rise, the traditional way of landfill no longer adapt society's development, henceforth life refuse shall be scientific processing, make it reutilized and create value. This paper explores the Guiyang city Wudang district kitchen garbage treat- ment equipment distribution design. We determine the position of each town by establishing the plane right angle coordinate system. If we presume to collect and transport on the center of the city, we can find out the number of equipment and the placement of the best coordinates according to the least Square method and MATLAB software.

  3. Design and Realization of the Inspection & Pick—up Equipment for Wafer Microchip%晶圆微芯片检查提取设备的设计与实现

    Institute of Scientific and Technical Information of China (English)

    郭俭; 林海涛; 毕秋吉

    2012-01-01

    介绍了晶圆微芯片检查提取设备的工艺流程和技术要求,设计了各部分结构,特别对芯片提取翻转放置机构进行了详细说明.介绍了富士PLC、触摸屏、伺服电机和E-SX总线在该设备中的应用,该系统通过E-SX总线将人机界面、控制器和执行器件连接,配线简单、维护方便、高速可靠.%This article describes the process and technical requirements of the inspection & pick—up equipment for wafer microchip and the design of each part of the structure, especially giving a detailed description on the chip pick-up and flipping mechanism. It also gives an introduction on application of Fuji PLC, touch screen, servo motor and E—SX bus in the equipment. The system connects human-machine interface, controls and actuator via E-SX bus, wiring simple featuring simple wiring, easy maintenance, high speed and reliability.

  4. Design Experience of the Lining-baking Equipment for New 260 t Mixing Bogie with Torpedo Retort%新型260 t鱼雷罐混铁车内衬烘烤装置的设计经验

    Institute of Scientific and Technical Information of China (English)

    杨薇萍

    2000-01-01

    在上海宝钢集团一钢公司2500m3高炉工程混铁车内衬烘烤装置的设计中,采用了高架金属软管供给煤气、稳焰烧嘴和计算机按预设工况进行自动烘烤的新技术,成功地将转炉煤气用于混铁车内衬烘烤作业。通过一年多的生产实践,充分显示了该装置具有结构简单、操作维护方便、安全可靠和烘烤效果好等优点。%The new techniques of overhead metallic hose for gas supply, steady-flame burner and computer-based automatic baking are atopted in the design of the lining-baking equipment of the mixing bogie for the 2500m3 blast furnace project at the First Steel Co. of Shanghai Baosteel Group Corp. ,and the gas from converter is successfully used for baking the bogie lining. Over more then one year production practice,it is shown that the equipment has simple structure,convenient operation and maintenance, reliable safety and good baking effectiveness.

  5. Design of the Ancillary Equipment for Spent Fuel Transport of PWR Nuclear Power Plant%压水堆核电站乏燃料运输辅助设备设计

    Institute of Scientific and Technical Information of China (English)

    瓮松峰

    2012-01-01

    In order to load and unload spent fuel assemblies safely in NPP, the ancillary equipment for spent fuel transport used to perform fluid transfer activities such as water feeding, air charging, and cask drying and heat rejection. This paper introduces the requirements, the scheme and the principle of the ancillary equipment, which adopts centralized-control and modular design, and have the performances such as higher work efficiency, higher safety, less radioactive substance accumulation and friendly man-machine conversation.%乏燃料运输辅助设备是用于对乏燃料运输容器进行充水排气、充气排水、充气风干的设备,并可对已装载乏燃料组件的容器进行充水冷却,实现乏燃料组件的安全装卸.本文介绍乏燃料运输辅助设备的功能要求、设计方案和工作原理.设备采用模块化设计和集中控制,具有工作效率高、结构简单、安全性高、不易积聚放射性物质和人-机交互友好的特点.

  6. On the Need for Reliable Seismic Input Assessment for Optimized Design and Retrofit of Seismically Isolated Civil and Industrial Structures, Equipment, and Cultural Heritage

    Science.gov (United States)

    Martelli, Alessandro

    2011-01-01

    Based on the experience of recent violent earthquakes, the limits of the methods that are currently used for the definition of seismic hazard are becoming more and more evident to several seismic engineers. Considerable improvement is felt necessary not only for the seismic classification of the territory (for which the probabilistic seismic hazard assessment—PSHA—is generally adopted at present), but also for the evaluation of local amplification. With regard to the first item, among others, a better knowledge of fault extension and near-fault effects is judged essential. The aforesaid improvements are particularly important for the design of seismically isolated structures, which relies on displacement. Thus, such a design requires an accurate definition of the maximum value of displacement corresponding to the isolation period, and a reliable evaluation of the earthquake energy content at the low frequencies that are typical of the isolated structures, for the site and ground of interest. These evaluations shall include possible near-fault effects even in the vertical direction; for the construction of high-risk plants and components and retrofit of some cultural heritage, they shall be performed for earthquakes characterized by very long return periods. The design displacement shall not be underestimated, but neither be excessively overestimated, at least when using rubber bearings in the seismic isolation (SI) system. In fact, by decreasing transverse deformation of such SI systems below a certain value, their horizontal stiffness increases. Thus, should a structure (e.g. a civil defence centre, a masterpiece, etc.) protected in the aforesaid way be designed to withstand an unnecessarily too large earthquake, the behaviour of its SI system will be inadequate (i.e. it will be too stiff) during much more frequent events, which may really strike the structure during its life. Furthermore, since SI can be used only when the room available to the structure

  7. Industrial electrical plant test equipment

    Energy Technology Data Exchange (ETDEWEB)

    Armanini, D.

    1991-06-01

    This paper surveys the principle types of less than 1,000 volt ac - 1,500 volt dc industrial/commercial electrical plant test equipment, currently marketed in Italy, and used by electrical system installers to test system conformity with CEI (Italian Electrotechnical Committee) norms. These test involve: the verification of conductor integrity, electrical insolation resistance measurements, automatic circuit breaking efficiency checking, etc. Outlines are given of the instruments' main design, operation and performance features. The various types of advanced and multi-use devices include - insolation and ground resistance gauges, failure ring resistance or impedance gauges, differential device testing equipment, leakage current and circuit resistance gauges, sequence scopes, and, finally, digital thermocouple temperature gauges.

  8. Effect of biomolecules adsorption on oxide layers developed on metallic materials used in cooling water systems

    International Nuclear Information System (INIS)

    This thesis was carried out in the frame of the BIOCOR ITN European project, in collaboration with the industrial partner RSE S.p.A. (Italy). Metallic materials commonly used in cooling systems of power plants may be affected by bio-corrosion induced by biofilm formation. The objective of this work was to study the influence of biomolecules adsorption, which is the initial stage of biofilm formation, on the electrochemical behaviour and the surface chemical composition of three metallic materials (70Cu-30Ni alloy, 304L stainless steel and titanium) in seawater environments. In a first step, the interactions between a model protein, the bovine serum albumin (BSA), and the surface of these materials were investigated. Secondly, tightly bound (TB) and loosely bound (LB) extracellular polymeric substances (EPS), that play a fundamental role in the different stages of biofilm formation, maturation and maintenance, were extracted from Pseudomonas NCIMB 2021 marine strain, and their effects on oxide layers were also evaluated. For that purpose, electrochemical measurements (corrosion potential E(corr) vs time, polarization curves and electrochemical impedance spectroscopy (EIS)) performed during the very first steps of oxide layers formation (1 h immersion time) were combined to surface analysis by X-ray photoelectron spectroscopy (XPS) and time-of-flight secondary ions mass spectrometry (ToF-SIMS). Compared to 70Cu-30Ni alloy in static artificial seawater (ASW) without biomolecules, for which a thick duplex oxide layer (outer redeposited Cu2O layer and inner oxidized nickel layer) is shown, the presence of BSA, TB EPS and LB EPS leads to a mixed oxide layer (oxidized copper and nickel) with a lower thickness. In the biomolecules-containing solutions, this oxide layer is covered by an adsorbed organic layer, mainly composed of proteins. A model is proposed to analyse impedance data obtained at E(corr). The results show a slow-down of the anodic reaction in the presence of

  9. Equipment selection for atmospheric drying

    International Nuclear Information System (INIS)

    Heavy water management is a major factor in deciding the economics of the PHWRs. Hence it is necessary to have an efficient recovery system, for the heavy water vapour escaping from various process systems and maintain a dry atmosphere in the recovery areas. While the basic objective of the atmospheric drying system is to maximize recovery and to minimize stack losses, it is equally important to optimally design the system with due consideration to operational and maintenance aspects. At present, heavy water vapour recovery in the existing Nuclear Power Plants (NPPs) is carried out by dryers of dual fixed bed design. While moving bed design could have some advantages, this has not been adopted so far because of the cumbersome mechanical design involved and special requirements for nuclear application. Developmental work done in this direction has resulted in compact alternative designs. In one of the designs, the change over from adsorption to regeneration is achieved by rotating the bed slowly. This concept is further refined in another alternative using a dessicant wheel. This paper contains brief equipment description of different designs; enumerates the design requirements of an atmospheric drying system for reactor building; describes steps for designing fixed bed type D2O vapour recovery system, and highlights advances in dryer technology. (author)

  10. 46 CFR 184.702 - Pollution prevention equipment and procedures.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Pollution prevention equipment and procedures. 184.702... Pollution prevention equipment and procedures. A vessel must comply with the applicable design, equipment, personnel, procedures, and record requirements of 33 CFR parts 151, 155, and 156....

  11. 29 CFR 1910.137 - Electrical protective equipment.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 5 2010-07-01 2010-07-01 false Electrical protective equipment. 1910.137 Section 1910.137... Electrical protective equipment. (a) Design requirements. Insulating blankets, matting, covers, line hose... portion of the glove. (2) Electrical requirements. (i) Equipment shall be capable of withstanding the...

  12. 21 CFR 110.40 - Equipment and utensils.

    Science.gov (United States)

    2010-04-01

    ... recording temperatures, pH, acidity, water activity, or other conditions that control or prevent the growth... Equipment § 110.40 Equipment and utensils. (a) All plant equipment and utensils shall be so designed and of... particles, dirt, and organic matter and thus minimize the opportunity for growth of microorganisms....

  13. 面向移动终端设备的学习APP的设计研究%Research on the Design of Learning APP for Mobile Terminal Equipment

    Institute of Scientific and Technical Information of China (English)

    范博; 于本成

    2015-01-01

    Birth of the Internet and mobile terminals mounted on mobile learning learning learning APP into a new trend, mobile learning can learn anytime, anywhere, on-demand occurs and also life-long learning, self-study and informal learning is an impor-tant one study, to further promote the rapid development of learning APP. Through the good experience of mobile learning and inter-active perspective, understand and analyze the current status of mobile learning systems development, trends and advantages, and disadvantages of, elaborate design and based on needs analysis and basic principles of the possible model designed to discuss the content, intended departure from the user needs to optimize learning APP is designed to improve the current shortcomings of the study of APP, it is part of the construction of a simple model to try, for research reference.%互联网与移动终端催生的移动学习搭载在学习APP上成为新兴学习潮流,移动学习可以使学习随时、随地、随需的发生,并且也是终身学习、自主学习与非正式学习的一种重要的学习方式之一,进一步促进了学习APP的迅猛发展.文章通过从移动学习的良好体验度和交互性的视角,了解分析了当前移动学习系统发展的现状、发展趋势和优势,以及存在的不足,详细阐述设计理念并依据需求分析和基本原则提出可能的模型设计来论述内容,旨在从用户需求出发优化学习APP的设计,以期改进目前学习APP的不足之处,是属于简单的模型建构尝试,仅供研究参考.

  14. 全自动单晶炉控制系统方案设计%Automatic Crystal Growth Equipment Control System Design

    Institute of Scientific and Technical Information of China (English)

    王庆; 张婷曼

    2011-01-01

    This design approach: using of general-purpose programmable logic controller(PLC),controlling and signal processing core by Beckhoff intelligent terminals,forming large-size touch screen friendly interface.carefully selecting advanced CCD measurement components and auxiliary surface temperature,etc.,completed of communication and control system through industrial field bus and Ethernet.%利用通用可编程控制器(PLC)、结合倍福(Beckhoff)智能端子作为控制和信号处理核心,以大尺寸触摸屏构成友好的人机界面。选用先进CCD测量元件及辅助液面测温等,通过工业现场总线加以太网完成整个系统的通讯及控制。

  15. 程控步进衰减器在通信测试设备上的设计应用%Design and Application of Programmable Step Attenuator in Communication Test Equipments

    Institute of Scientific and Technical Information of China (English)

    赵李华; 李渊

    2014-01-01

    Signal program-controlled attenuator regulation and level control function can be widely used in communications test equipment. Now, a new wideband programmable step attenuator, designed by monolithic integrated attenuator with MMIC HMC472LP4E, has advantages of larger dynamic attenuation range and excellent attenuation accuracy and so on.%程控衰减器的信号调节和电平控制功能可广泛应用于通信测试设备中,而利用HMC472LP4E单片集成衰减器设计的一款宽带程控步进衰减器,更具有较大的动态衰减范围、优良的衰减精度等优点。

  16. Electronic equipment packaging technology

    CERN Document Server

    Ginsberg, Gerald L

    1992-01-01

    The last twenty years have seen major advances in the electronics industry. Perhaps the most significant aspect of these advances has been the significant role that electronic equipment plays in almost all product markets. Even though electronic equipment is used in a broad base of applications, many future applications have yet to be conceived. This versatility of electron­ ics has been brought about primarily by the significant advances that have been made in integrated circuit technology. The electronic product user is rarely aware of the integrated circuits within the equipment. However, the user is often very aware of the size, weight, mod­ ularity, maintainability, aesthetics, and human interface features of the product. In fact, these are aspects of the products that often are instrumental in deter­ mining its success or failure in the marketplace. Optimizing these and other product features is the primary role of Electronic Equipment Packaging Technology. As the electronics industry continues to pr...

  17. Medical Issues: Equipment

    Science.gov (United States)

    ... strollers also have trays to carry medical equipment. Bath Chairs Specialized bath chairs provide comfortable and secure bathing for children and small adults with special needs. Bath chairs are adjustable, with multiple seat and back angles. ...

  18. 煤矿设备信息管理系统的构件化设计方法%Component Design Method of Information Management System of Mine Equipment

    Institute of Scientific and Technical Information of China (English)

    王维

    2012-01-01

    针对现有的煤矿设备信息管理系统开发效率和复用粒度低、难以满足煤矿个性需求的问题,从软件复用的角度介绍了一种煤矿设备信息管理系统的构件化设计方法,给出了系统开发模型和体系结构,详细介绍了系统构件的设计和实现方法.该构件化设计方法通过创建.NET功能构件,复用.NET中的基本构件和已创建的功能构件,最后在.NET开发平台上组装构件来达到软件复用的目的,提高了系统软件的开发效率、可靠性和可重用性.%In order to solve problems of low developing efficiency and reusing granularity of existing information management system of coal equipment which cannot meet personalized demands of coal mine, the paper introduced a component design method of information management system of coal equipment in term of software reuse, gave developing model and structure of the system, and introduced design and implementation of system component in details. The method achieves the purpose of software reuse by creating . NET functional components, reusing basic .NET components and the functional components and assembling the components on .NET development platform. The method improves developing efficiency, reliability and reusability of system software.

  19. 棉麻纤维液氨改性成套装备上下物料系统设计%Design of Material Loading and Unloading System for Liquid Ammonia Treatment Equipment of Cotton and Linen Fiber

    Institute of Scientific and Technical Information of China (English)

    张凯

    2012-01-01

    摘要:目前棉麻纤维液氨改性系统的上下料采用人工方式进行,存在工作效率低、工人劳动强度大的缺点,基于发明问题解决理论(TRIZ)对液氨改性成套装备物料输送系统进行了创新设计,采用对心曲柄齿轮齿条机构和电磁铁来实现物料箱在小空间长行程的上下料,采用欧姆龙公司的CPlL型PLC来实现整个系统的控制,可实现棉麻纤维液氨改性成套装备物料包装输送系统的自动化。%The currently using material loading and unloading system for liquid ammonia treatment equipment of cot- ton and linen fiber has shortcomings of low efficiency and high labor intensity. In order to get rid of these shortcomings and based on TRIZ theory, the innovative design of complete material delivery system for liquid ammonia treatment e- quipment was made. The design realized material loading and unloading in small space and long distance by using heart crank gear rack mechanism and solenoids. Type CP1 L PLC from Omron was used to control of the entire system, to realize automation of material delivery system for liquid ammonia treatment equipment of cotton and linen fiber.

  20. Development of Virtual Equipment for a Hydraulic Mechanics Experiment

    Institute of Scientific and Technical Information of China (English)

    CHAN Ying-Chieh; CHEN Ya-Hsin; KANG Shih-Chung; LEE Tim-Hau

    2008-01-01

    Laboratory class is very important in the education of hydraulic mechanics. However, it usually requires a high expenditure on equipment purchase and maintenance. Virtual equipment that renders the equipment in a virtual world and provides an interactive interface for users can be an ideal solution to reduce costs. In this research, we focus on developing virtual equipment for a Venturi tube experiment. We em-ployed multiple paper-prototypes to gather user feedback on the preliminary design. Following the final pro-totype, we then implemented the virtual equipment on computers. Interactive functions have been built into the virtual equipment. Users are able to manipulate the equipment and obtain real-time feedback as if they were using actual equipment. The results show that the development of the virtual equipment is technically feasible.

  1. 发酵设备课程设计教学中抄袭现象的研究%Course Design of Plagiarism Phenomenon in Fermentation Engineering and Equipment

    Institute of Scientific and Technical Information of China (English)

    张超; 陈文兵; 武道吉; 侯书国; 郑晓吉

    2015-01-01

    As an important link of practice teaching, the fermentation engineering and equipment course design can play the connecting role between the preceding and the following in the practice teaching, and lay a good foundation for the students to work in the factory after graduation. There exist all different plagiarism phenomenon during the course design. The article shall exchange and discuss the teaching links, such as the status, opinion, contents and way of the course design.%发酵设备课程设计是重要的实践教学环节,在实践教学中起到衔接作用,可为学生进入工作岗位打下良好基础。但在课程设计教学过程中,学生之间存在不同程度的抄袭现象,对课程设计中抄袭现象产生的原因、解决方法和效果等各环节进行交流与探讨。

  2. Overview on water supply and drainage system design of China Spallation Neutron Source(CSNS)equipment%中国散裂中子源通用设施给排水设计概述

    Institute of Scientific and Technical Information of China (English)

    李建俊

    2014-01-01

    Combining with water supply and drainage design example of CSNS equipment,the paper outlines the water supply and drainage design of scientific device,and introduces design parameters and components of recycling cooling water system,pure water fabrication system,low emis-sion waste water collection and drainage system,which has important meaning for further improving scientific development.%结合中国散裂中子源通用设施给排水设计实例,对大科学装置给排水设计进行了综述,介绍了工艺循环冷却水系统、纯水制备系统、低放废水的收集及排放系统的设计参数与构成要素,对进一步促进科技的发展具有重要的意义。

  3. Real-time monitoring and manipulation of single bio-molecules in free solution

    Energy Technology Data Exchange (ETDEWEB)

    Li, Hung-Wing [Iowa State Univ., Ames, IA (United States)

    2005-01-01

    The observation and manipulation of single biomolecules allow their dynamic behaviors to be studied to provide insight into molecular genetics, biochip assembly, biosensor design, DNA biophysics. In a PDMS/glass microchannel, a nonuniform electroosmotic flow (EOF) was created. By using a scanning confocal fluorescence microscope and total internal-reflection fluorescence microscope (TIRFM), we demonstrated that negatively charged DNA molecules were focused by the nonuniform EOF into a thin layer at the glass surface. This phenomenon was applied to selectively detect target DNA molecules without requiring the separation of excessive probes and can be applied continuously to achieve high throughput. A variable-angle-TIRFM was constructed for imaging single DNA molecule dynamics at a solid/liquid interface. Implications we have are that the measured intensities cannot be used directly to determine the distances of molecules from the surface and the experimental counting results depict the distance-dependent dynamics of molecules near the surface; Molecules at low ionic strengths experience electrostatic repulsion at distances much further away from the surface than the calculated thickness of the electrical double layer. {delta}-DNA was employed as a nanoprobe for different functionalized surfaces to elucidate adsorption in chromatography. The 12-base unpaired ends of this DNA provide exposed purine and pyrimidine groups for adsorption. Patterns of self-assembled monolayers (SAMs) and patterns of metal oxides are generated. By recording the real-time dynamic motion of DNA molecules at the SAMs/aqueous interface, the various parameters governing the retention of an analyte during chromatographic separation can be studied. Even subtle differences among adsorptive forces can be revealed. Dynamic conformational changes of the prosthetic group, flavin adenine dinucleotide (FAD), in flavoprotein NADH peroxidase, in thioredoxin reductase, and in free solution were monitored

  4. Incidents of chemical reactions in cell equipment

    Energy Technology Data Exchange (ETDEWEB)

    Baldwin, N.M.; Barlow, C.R. [Uranium Enrichment Organization, Oak Ridge, TN (United States)

    1991-12-31

    Strongly exothermic reactions can occur between equipment structural components and process gases under certain accident conditions in the diffusion enrichment cascades. This paper describes the conditions required for initiation of these reactions, and describes the range of such reactions experienced over nearly 50 years of equipment operation in the US uranium enrichment program. Factors are cited which can promote or limit the destructive extent of these reactions, and process operations are described which are designed to control the reactions to minimize equipment damage, downtime, and the possibility of material releases.

  5. Design of Rolling Balance Experimental Equipment for LowSpeed Wind Tunnel%低速风洞旋转天平试验装置的设计

    Institute of Scientific and Technical Information of China (English)

    杨恩霞; 庞永刚; 刁彦飞

    2001-01-01

    By way of simulating trial of plane model whirligig in windtunnel by use of rolling balance and measuring the aerodynamic force on circumvoluting model,we can analyse the trial spinning characteristic.This is one of the efficient way. The paper introduced the working prinnciple and structural design of rolling balance for low speed wind tunnelindetail.%应用旋转天平使飞机模型在风洞里模拟飞机尾旋时的旋转运动,并测量出旋转模型上的气动力,从而对飞机的尾旋特性进行分析、预测,这是研究飞机尾旋特性的有效方法之一。较为详细地介绍了低速风洞旋转天平的工作原理及结构设计。

  6. 同种异体骨切割设备夹持装置的设计%Design of Gripping Device of Allogeneic Bone Cutting Equipment

    Institute of Scientific and Technical Information of China (English)

    方新果; 萨拉; 赵改平; 王晨曦; 柏磊磊

    2014-01-01

    Based on bionic principle and the mechanics analysis of bone implant materials,a mechanics model for hand clamping structure with six degrees of freedom is established and a gripping device for bone cutting is designed. It is suitable for the processing of bone materials of irregular shapes and can meet requirements for va-rious specific clinic products. In addition,the operation safety and the efficiency of bone material utilization are both improved.%根据对骨植入材料的力学分析,从仿生学原理入手,建立六自由度的手夹持结构的力学模型,设计了骨切割设备夹持手机械结构。它能适应不规则形状骨材料的加工,满足临床对不同规格产品的需求,可提高操作的安全性、骨料的利用率。

  7. Recent advances in chemical functionalization of nanoparticles with biomolecules for analytical applications.

    Science.gov (United States)

    Oh, Ju-Hwan; Park, Do Hyun; Joo, Jang Ho; Lee, Jae-Seung

    2015-11-01

    The recent synthetic development of a variety of nanoparticles has led to their widespread application in diagnostics and therapeutics. In particular, the controlled size and shape of nanoparticles precisely determine their unique chemical and physical properties, which is highly attractive for accurate analysis of given systems. In addition to efforts toward controlling the synthesis and properties of nanoparticles, the surface functionalization of nanoparticles with biomolecules has been intensively investigated since the mid-1990s. The complicated yet programmable properties of biomolecules have proved to substantially enhance and enrich the novel functions of nanoparticles to achieve "smart" nanoparticle materials. In this review, the advances in chemical functionalization of four types of representative nanoparticle with DNA and protein molecules in the past five years are critically reviewed, and their future trends are predicted.

  8. Immobilization of biomolecules onto surfaces according to ultraviolet light diffraction patterns

    DEFF Research Database (Denmark)

    Petersen, Steffen B.; Gennaro, Ane Kold Di; Neves Petersen, Teresa;

    2010-01-01

    We developed a method for immobilization of biomolecules onto thiol functionalized surfaces according to UV diffraction patterns. UV light-assisted molecular immobilization proceeds through the formation of free, reactive thiol groups that can bind covalently to thiol reactive surfaces. We...... demonstrate that, by shaping the pattern of the UV light used to induce molecular immobilization, one can control the pattern of immobilized molecules onto the surface. Using a single-aperture spatial mask, combined with the Fourier transforming property of a focusing lens, we show that submicrometer (0.7 mu...... m) resolved patterns of immobilized prostate-specific antigen biomolecules can be created. If a dual-aperture spatial mask is used, the results differ from the expected Fourier transform pattern of the mask. It appears as a superposition of two diffraction patterns produced by the two apertures...

  9. Immobilization of biomolecules onto surfaces according to ultraviolet light diffraction patterns

    Energy Technology Data Exchange (ETDEWEB)

    Bjoern Petersen, Steffen; Kold di Gennaro, Ane; Neves-Petersen, Maria Teresa; Skovsen, Esben; Parracino, Antonietta

    2010-10-01

    We developed a method for immobilization of biomolecules onto thiol functionalized surfaces according to UV diffraction patterns. UV light-assisted molecular immobilization proceeds through the formation of free, reactive thiol groups that can bind covalently to thiol reactive surfaces. We demonstrate that, by shaping the pattern of the UV light used to induce molecular immobilization, one can control the pattern of immobilized molecules onto the surface. Using a single-aperture spatial mask, combined with the Fourier transforming property of a focusing lens, we show that submicrometer (0.7 {mu}m) resolved patterns of immobilized prostate-specific antigen biomolecules can be created. If a dual-aperture spatial mask is used, the results differ from the expected Fourier transform pattern of the mask. It appears as a superposition of two diffraction patterns produced by the two apertures, with a fine structured interference pattern superimposed.

  10. Manufacture and maintenance of laboratory equipment

    Energy Technology Data Exchange (ETDEWEB)

    Kim, J. K.; Whang, C. K.; Lee, J. H.; Youm, K. Y.; Hong, S. H.; Choi, H. Y.; An, C.; Park, I. W.; Kim, K. S.; Lee, W. J.; Yoon, K. B.; Kim, H. W.; Lee, I. B.; Lee, C. K.; Youm, J. H.; Oho, W. H.; Choi, B. K.; Jang, K. D.

    1996-12-01

    This report on the manufacture and maintenance of laboratory equipment contains working contents, scope and contents of a request working to the Machine Shop, also records the principal production design, manufacture contents and a relevant working drawing. The working content and scope of the Machine Shop is to support the successful and convenient performance of the R and D by manufacture and maintenance of all sorts of laboratory equipment. (author). 9 tabs., 12 figs.

  11. Manufacture and maintenance of laboratory equipment

    Energy Technology Data Exchange (ETDEWEB)

    Hwang, Chang Kyu; Hwang, Bong Ha; Lee, Jong Wha; Kim, Jong Kyun; Yeum, Ki Eon; Park, Myung Ku; Hong, Soon Eon; Choi, Ho Young; An, Dae Kyu; An, Choon; Park, In Won; Kim, Kyung Sik; Lee, Won Jae; Yoon, Ki Byung; Kim, Heung Woo; Lee, In Bae; Yeom, Jeong Hyun; Lee, Chul Ku; Sin, Keon Ju; Oh, Wan Ho; Seo, Yong Chil; Yang, Song Yeul; Lee, Young Soon; Choi, Byung Kwon; Chang, Kyung Duk [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)

    1993-12-01

    This report on the manufacture and maintenance of laboratory equipment contains working contents, scope and contents of request working to the machine shop, also records the principal production design, manufacture contents and a relevant working drawing. The working content and scope of the machine shop is to support the successful and convenient performance of the R and D by manufacture and maintenance of all sorts of laboratory equipment. 11 tabs., 3 figs. (Author) .new.

  12. Manufacture and maintenance of laboratory equipment

    International Nuclear Information System (INIS)

    This report on the manufacture and maintenance of laboratory equipment contains working contents, scope and contents of a request working to the Machine Shop, also records the principal production design, manufacture contents and a relevant working drawing. The working content and scope of the Machine Shop is to support the successful and convenient performance of the R and D by manufacture and maintenance of all sorts of laboratory equipment. (author). 9 tabs., 12 figs

  13. Programmable and autonomous computing machine made of biomolecules

    Science.gov (United States)

    Benenson, Yaakov; Paz-Elizur, Tamar; Adar, Rivka; Keinan, Ehud; Livneh, Zvi; Shapiro, Ehud

    2001-11-01

    Devices that convert information from one form into another according to a definite procedure are known as automata. One such hypothetical device is the universal Turing machine, which stimulated work leading to the development of modern computers. The Turing machine and its special cases, including finite automata, operate by scanning a data tape, whose striking analogy to information-encoding biopolymers inspired several designs for molecular DNA computers. Laboratory-scale computing using DNA and human-assisted protocols has been demonstrated, but the realization of computing devices operating autonomously on the molecular scale remains rare. Here we describe a programmable finite automaton comprising DNA and DNA-manipulating enzymes that solves computational problems autonomously. The automaton's hardware consists of a restriction nuclease and ligase, the software and input are encoded by double-stranded DNA, and programming amounts to choosing appropriate software molecules. Upon mixing solutions containing these components, the automaton processes the input molecule via a cascade of restriction, hybridization and ligation cycles, producing a detectable output molecule that encodes the automaton's final state, and thus the computational result. In our implementation 1012 automata sharing the same software run independently and in parallel on inputs (which could, in principle, be distinct) in 120μl solution at room temperature at a combined rate of 109 transitions per second with a transition fidelity greater than 99.8%, consuming less than 10-10W.

  14. Modeling Complex Systems From First Principles: From Nanocrystals to Biomolecules

    International Nuclear Information System (INIS)

    The microscopic behavior of matter, which is governed by the law of quantum mechanics, can now be accurately modeled with the use of sophisticated techniques and computers of increasing power. Starting from ''first principles,'' i.e., simply from the knowledge of which atoms are in the system of interest, it is possible to calculate precisely how the atoms in molecules and materials interact, move, and react to external stimuli, such as pressure, light, or radiation. First principles methods are extremely versatile and useful not only to elucidate and understand known phenomena, but also to predict and discover new ones. Among first principles methods, density functional theory, thanks to its favorable ratio between accuracy and computational cost, is a very successful technique for describing structural and electronic properties of systems of physical, chemical, materials science, and biological interest. To illustrate the power of this first principles method, selected examples of simulations based on density functional theory, ranging from semiconductor nanocrystals and computer-designed polymers to photoactive proteins and neuroreceptors, are presented

  15. Design and realization for automatic calibration of test equipment information exchange platform%自动化标定测试设备信息交互平台设计与实现

    Institute of Scientific and Technical Information of China (English)

    万志江; 高辉文; 吴静

    2012-01-01

    On traditional demarcation turntable, the transmission and the extraction of the inertial integrated information usually depend on the multi-channel links, the tie cable as well as the gathering card based on ISA, PCI, PXI or VXI bus. However, the usability of equipment is significantly influenced by the turntable's big size, high cost, low test-efficiency, and restricted demarcation flow. In this paper, a new solution scheme is provided based on the information exchange platform of automated calibration & test equipment. It adopts the embedded system-on-chip design, communication protocol design, fault tolerance and work pattern recognition and many other technologies for automated, intelligent and precision of calibration. The automation calibration equipment with the new design do not need the processes such as resetting the counter, turning back to zero and implementing initialization after starting up, and this provides the technical supports for shortening the calibration and test time (from 4 hours to 1.5 hours), flexibly calibrating the test procedures, reducing the cost of turntable (12 slippery ring road reduced to 2), reduce the equipment size, and obtaining accurate integrated measurement information.%传统标定转台往往依靠设备内部多路滑环、连接电缆以及基于ISA、PCI、PXI或VXI总线的采集卡进行惯测组合信息的传输和提取,转台体积大、成本高、标定流程受限以及测试效率低等因素极大影响了设备的使用性,基于自动化标定测试设备的信息交互平台,采用了嵌入式片上系统设计、通信协议设计、容错处理以及工作模式识别等多项技术,为实现自动化、智能化以及精准化标定提供了新的解决方案,采用新方案设计的自动化标定设备启动后无需再进行计数清零、转位回零以及初始化处理,为缩短标定测试时问(由4h缩短到1.51h),灵活的进行标定测试走位以及流程编排,降低转台成本(12

  16. Submicron machining and biomolecule immobilization on porous silicon by electron beam.

    Science.gov (United States)

    Imbraguglio, Dario; Giovannozzi, Andrea Mario; Nastro, Annalisa; Rossi, Andrea Mario

    2012-09-25

    Three-dimensional submicrometric structures and biomolecular patterns have been fabricated on a porous silicon film by an electron beam-based functionalization method. The immobilized proteins act as a passivation layer against material corrosion in aqueous solutions. The effects' dependence on the main parameters of the process (i.e., the electron beam dose, the biomolecule concentration, and the incubation time) has been demonstrated.

  17. Cold-spray Ionization Mass Spectrometry for Characterization of Biomolecules in Solution

    Institute of Scientific and Technical Information of China (English)

    Kentaro YAMAGUCHI; Shigeru SAKAMOTO

    2003-01-01

    @@ A direct solution analysis method, coldspray ionization (CSI) mass spectrometry (MS)[1], a variant of electrospray (ESI) MS operating at low temperature (ca. - 80 ~ 10℃), allows facile and precise characterization of labile organic species, especially those in which non-covalent bonding interactions are prominent. We have applies this method to investigations of the solution structures of many labile organic species, including unstable reagents and reaction intermediates, asymmetric catalysts, supramolecules, and even primary biomolecules.

  18. Imparting biomolecules to a metal-organic framework material by controlled DNA tetrahedron encapsulation

    OpenAIRE

    Yongmei Jia; Benmei Wei; Ruixue Duan; Ying Zhang; Boya Wang; Abdul Hakeem; Nannan Liu; Xiaowen Ou; Shaofang Xu; Zhifei Chen; Xiaoding Lou; Fan Xia

    2014-01-01

    Recently, the incorporation of biomolecules in Metal-organic frameworks (MOFs) attracts many attentions because of controlling the functions, properties and stability of trapped molecules. Although there are few reports on protein/MOFs composites and their applications, none of DNA/MOFs composite is reported, as far as we know. Here, we report a new composite material which is self-assembled from 3D DNA (guest) and pre-synthesized MOFs (host) by electrostatic interactions and hydrophilic inte...

  19. Design and testing of head-stem segregation equipment for garlic%大蒜果秧分离试验装置的设计与测试

    Institute of Scientific and Technical Information of China (English)

    于昭洋; 胡志超; 王海鸥; 彭宝良; 谢焕雄; 吴峰

    2013-01-01

    Garlic is one of the major cash crops in China. Production, acreage, and exports of garlic in China are the highest in the world. As a seasonal operation, garlic harvesting in China is still mainly manual work, having the problems of low efficiency, high labor intensity, and huge occupation of farming season, which has constrained the further development of the garlic industry. The current domestic garlic harvesters are basically simple segmented machinery. The techniques of garlic combine harvesting is still in its infancy. Picking is the core technology on garlic combine harvesting, but it has not been refined well. In order to enhance operational performance of picking, a new kind of garlic picking testbed was designed to carry out the studies on optimization design on structural and working parameters of a garlic-picking device. Lower damage and less stem are the two primary objectives in garlic harvesting. The garlic picking testbed consists of a clamping delivery device, a ranking/alignment device, a cutter, and an electric control system, which carry out garlic clamping, transport, ranking, alignment, and cutting at one time. The clamping delivery device of which core components are front track and middle track uses two tooth-shaped chains. Through the guidance of the two tracks, the trajectory and clamping style of the chains is changed, achieveing the transition from double chain clamping to chain-board-hairbrush clamping, The core components of the ranking/alignment devices are guidance rods, a ranking disk, finger, an alignment chain, and a hairbrush. In the test, the garlic was artificially fed. First, garlic plants are gripped by the clamping delivery device and transported backward. Under the interaction of ranking/alignment devices and clamping/delivery devices, garlic plants are ranked automatically and garlic bulbs are aligned automatically. After the garlic bulbs are aligned, garlic stems are cut by disc cutters to achieve garlic bulbs whose stems

  20. "Design and synthesis of relevant biomolecules for functionalization of biomaterial in tissue engineering"

    OpenAIRE

    Shaikh

    2011-01-01

    Carbohydrates, glycoconjugates, and oligosaccharides are critical components of living systems and mediate a vast number of fundamental biological processes from complex cellular operations required to initiate and sustain life, to recognition events that are responsible for autoimmune diseases, organ rejection, and inflammation. This functional diversity is reflected in the diversity of carbohydrate structures. There is an increasing demand for efficient access to oligosacchar...

  1. Graphene-Templated Synthesis of Magnetic Metal Organic Framework Nanocomposites for Selective Enrichment of Biomolecules.

    Science.gov (United States)

    Cheng, Gong; Wang, Zhi-Gang; Denagamage, Sachira; Zheng, Si-Yang

    2016-04-27

    Successful control of homogeneous and complete coating of graphene or graphene-based composites with well-defined metal organic framework (MOF) layers is a great challenge. Herein, novel magnetic graphene MOF composites were constructed via a simple strategy for self-assembly of well-distributed, dense, and highly porous MOFs on both sides of graphene nanosheets. Graphene functionalized with magnetic nanoparticles and carboxylic groups on both sides was explored as the backbone and template to direct the controllable self-assembly of MOFs. The prepared composite materials have a relatively high specific surface area (345.4 m(2) g(-1)), and their average pore size is measured to be 3.2 nm. Their relatively high saturation magnetization (23.8 emu g(-1)) indicates their strong magnetism at room temperature. Moreover, the multifunctional composite was demonstrated to be a highly effective affinity material in selective extraction and separation of low-concentration biomolecules from biological samples, in virtue of the size-selection property of the unique porous structure and the excellent affinity of the composite materials. Besides providing a solution for the construction of well-defined functional graphene-based MOFs, this work could also contribute to selective extraction of biomolecules, in virtue of the universal affinity between immobilized metal ions and biomolecules. PMID:27046460

  2. About Personal Protective Equipment (PPE)

    Science.gov (United States)

    ... Equipment for Infection Control Questions About Personal Protective Equipment (PPE) Share Tweet Linkedin Pin it More sharing ... Print Q1. How do manufacturers ensure personal protective equipment (PPE) is safe and effective? A1. To help ...

  3. Biomolecule mediating synthesis of inorganic nanoparticles and their applications

    Science.gov (United States)

    Wei, Zengyan

    rationally predict and design nanoparticle shapes. Here we introduce a methodology to fabricate nanoparticles in smaller sizes by evolving shapes thermodynamically. This strategy enables a more rational approach to fabricate shaped nanoparticles by etching specific positions of atoms on facets of seed nanocrystals in reverse micelle reactors where the surface energy gradient induces desorption of atoms on specific locations on the seed surfaces. From seeds of 12 nm palladium nanocubes, the shape is evolved to concave nanocubes and finally hollow nanocages in the size 10 nm by etching the center of {200} facets. The high surface area-to-volume ratio and the exposure of a large number of palladium atoms on ledge and kink sites of hollow nanocages are advantageous to enhance catalytic activity and recyclability.

  4. Elemental labelling combined with liquid chromatography inductively coupled plasma mass spectrometry for quantification of biomolecules: A review

    OpenAIRE

    Kretschy, Daniela; Koellensperger, Gunda; Hann, Stephan

    2012-01-01

    This article reviews novel quantification concepts where elemental labelling is combined with flow injection inductively coupled plasma mass spectrometry (FI-ICP-MS) or liquid chromatography inductively coupled plasma mass spectrometry (LC–ICP-MS), and employed for quantification of biomolecules such as proteins, peptides and related molecules in challenging sample matrices. In the first sections an overview on general aspects of biomolecule quantification, as well as of labelling will be pre...

  5. Establishment of nuclear equipment qualification system

    Energy Technology Data Exchange (ETDEWEB)

    Joo, Po Kook; Lim, Nam Jin; Lee, Young Gun [and others

    2003-04-01

    This study is carried out by KEARI(Korea Atomic Energy Research Institute) as the lead organization in cooperation with KIMM(Korea Institute of Machinery and Materials), KTL(Korea Testing Laboratory) and KRISS(Korea Research Institute of Standards and Science) to construct a basis of efficient management of nuclear equipment qualification business by expanding test equipment of each of participating organization, and developing qualification technologies. As for KIMM, control system of large scale shaker was replaced with advanced system, and LOCA(Loss of Coolant Accident) test facility was installed. KTL is now capable of conducting seismic tests of nuclear I and C as a result of installation of seismic test equipment during the first two project years. KRISS participated in the Project with a view to have large scale EMI test equipment and related technologies. In parallel with expansion of test equipment, a industrial-educational-research cooperation committee, as an intermediate step toward integrated equipment qualification system to maximize the usage of test equipment, was established and cooperation methods were investigated. As a result, Korea Nuclear Equipment Qualification Association, an corporate juridical person, was established. Research on development of thermal and radiation aging test technology of nuclear materials was carried out by Hanyang University and SECO(Saehan Engineering and Qualification Co., Ltd.). Integrated Equipment Qualification Database was developed which contains material test data, equipment qualification data and other EQ related informations. Standard qualification procedures were developed in order for test laboratories and manufacturers to establish design requirements and to efficiently perform tests.

  6. 卷烟包装设备专用零件参数化CAD系统开发%Development of a parametric designing CAD system for parts special for cigarette packing equipment

    Institute of Scientific and Technical Information of China (English)

    吴旭; 何霄峰; 甘蔚钰

    2009-01-01

    在Pro/E软件环境下,利用二次开发工具Pro/Tookit结合Pro/E的布局功能开发了一套针对卷烟包装设备的专用零件参数化CAD系统.该系统具有便捷的用户菜单,通过修改布局文件中烟包、烟条规格参数,可以对卷烟包装设备专用零件进行自动参数化设计,并输出相应的三维零件图、三维装配图和二维工程图.同时,系统实现了零件的自动设计和装配检验,大大缩短了产品的开发时间,提高了设计效率.%Based on Pro/Engineering software, a parametric designing CAD system for parts specially used in cigarette packaging equipment had been developed by Pro/Toolkit and the Layout function. A user-friendly menu was provided in the system. The parametric part de-signing for the parts could be conducted by changing the parameters in the layout. And the 3D part models, 3D assembly models and 2D engineering drawings could also be output. Au-tomatic part designing and assembly testing had been realized in the system, which could greatly shorten the product's development time and improve the design quality.

  7. Design for Testability of Missile Weapon Equipment Based on Missile Data Bus%基于弹上总线的导弹装备测试性设计方法

    Institute of Scientific and Technical Information of China (English)

    胥辉旗; 田燕妮; 陈望达

    2012-01-01

    为克服传统测试方法在测试数字电路板时的技术障碍,提出基于弹上总线及边界扫描的弹上设备机内自测试设计方案.在介绍IM总线(module test and maintenance bus,TM Bus)和边界扫描的基础上,论述系统测试性设计的基本概念,搭建测试试验系统,并对系统测试性设计概念和主要考核指标进行演示、验证.结果表明:该设计能简化导弹的测试流程,提高导弹武器系统的可靠性、维修性和测试性.%To overcome the technology barriers of the traditional test method in testing digital circuit board, put forwards a new design scheme of missile equipment built-in self-testing based on missile data bus and boundary scan. Discuss the basic concept of system testing by introduce of the module test and maintenance bus (TM Bus) and boundary scan. A test system is designed to illustrate the concept and test the main indicators of design for testability (DFT). Performance testing indicates that the design can simplify testing process and improve the reliability, maintainability and testability of missile weapon system.

  8. Modulation of the captopril interference with the activity of some enzymatic biomolecules in monkey kidney vero cells by drug delivery mesoporous silica system

    Directory of Open Access Journals (Sweden)

    Roxana Popovici

    2011-12-01

    Full Text Available The in vitro effect of different formulations of captopril on some cellular enzymatic equipments activities of monkey kidney Vero cells was investigated in the present research. The preparation of the samples of the mesoporous silica nanocomposites, loaded or not with captopril, was described and their effect on membranary Na+-K+-ATP-ase, cell Mg2+-ATP-ase, LDH, Px, GSH-Px, SOD, CAT, ACP, ALP activities were studied. The Vero cells were incubated, for a period of 144 hours, with growing medium renewed twice. When the cells reached confluence in the monolayer stage, the cultures were divided into control cell cultures and other 4 treated groups. To the 12 hours treated cells were added: Cap H2, SBA–15, unfunctionalized SBA-15_CapH2_RT and functionalized SBA-15_APTES_CapH2_80°C nanocomposites, each of them in a dose of 0.4μg./flask. As compared with the control Vero cells, which are characterized by a specific level of the enzymatic activities, the cultures treated with SBA-15 have not presented significant alterations of them. The comparative study of captopril interactions with some membrane bound and intracellular enzymatic biomolecules of monkey kidney Vero cells has revealed either an enhancement of membranary Na+-K+-ATP-ase, intracell total ATP- ase , LDH, ACP , and GSH-Px activities or a repression of cellular CAT, Px and SOD activities. These variations of the enzymatic activities – which induce modifications of the membranary and metabolic processes – could be due to a direct or indirect interaction of captopril with cellular (plasmalemma or subcellular (organelles structures and with intracellular biomolecules (enzymes, DNA, RNA etc.. The association of captoptil with SBA – 15 or SBA – 15 _ APTES mesoporous silica matrices and treatment of Vero cells with these nanocomposites were correlated with modulation of the captopril interference with the activity of investigated enzymatic biomolecules, its sense (stimulation or

  9. The design and analysis of the main equipment in combination of solar drying system%太阳能组合干燥系统主体设备的设计与分析

    Institute of Scientific and Technical Information of China (English)

    王文茹; 董继先; 李靖

    2016-01-01

    In this paper,we take the combination of drying equipment for example,For drying non-uniformity problem of the combination drying oven and solar collector selection prob-lem,we analyze the type of solar collector that is used for it,and calculate detailedly the col-lector area,collection of heat energy and recovery period of them.Finally,we optimize the type and structure of the selected collector in Xi′an area,and provide the basis for drying e-quipment to make better use of solar energy.For the unevenness problem in the combination of hot air drying oven.To achieve the uniformity of material drying to further enhance dry material quality and provide help for further study on the combination of drying equipment, we put forward improvement scheme and carry on the reasonable design by changing the way of hot air into the combination for hot air vacuum drying oven.%以太阳能组合干燥设备为例,针对组合干燥箱内热风干燥不均匀性问题以及太阳能集热器的选型问题通过对太阳能集热器的类型进行了分析,详细地计算了它们的集热面积、集热能量以及回收年限,最后优化出在西安地区选用集热器的类型和结构,并通过改变热风进风方式对热风真空组合干燥箱提出改进方案,最终实现物料干燥的均匀性及物料干燥品质进一步提高的目的。优化组合干燥设备为干燥设备更好地利用太阳能及组合干燥设备的进一步研究提供依据。

  10. 试验用低温巴氏杀菌设备设计与性能测试%Design and Performance Test of Low-temperature Pasteurization Equipment for Experiment

    Institute of Scientific and Technical Information of China (English)

    刘文营; 王飞; 郭立华; 黄丽燕; 赵维高; 卢晓明

    2013-01-01

    In order to promote the application of low-temperature pasteurization in the heat thermosensitive materials, the equipment was designed. The design principle, its structural characteristics and processes were proposed, and the thermal power, heat transfer and flow resistance were analyzed. The maximum processing capacity was 13 800 mL/h with 230 mL/min of maximum flow velocity. Taking water as treatment material, the temperature of water can reach to 52℃ from 4℃ in 4. 5 s, and reduce to 20℃ from 52℃ in 3 s or 10t in 6 s. And the bacterium concentration of liquid egg white could lessen to 100 CFU/mL in 2.5 min at 55℃. The performance test shows that the system possesses a good heat-transfer capability, and a high sterilizing effect. Results provide the technical basis for the design and manufacture of low-temperature pasteurization equipment.%设计了一套试验用低温巴氏杀菌设备,阐述了设备的工作原理、主体结构和工作过程,计算了设备的传热能力.依据蠕动泵规格参数,设备最大流量为230 mL/min,最大处理能力为13 800 mL/h.采用水为处理物料,经传热能力计算可知设备满足物料的升温需要,且可以实现在4.5s内从4℃到52℃的升温,以及3 s内52℃到20℃和6s内52℃到10℃的降温.蛋清液杀菌试验表明,在55℃条件下,2.5 min可以实现菌体浓度降为100 CFU/mL.性能试验显示:设备传热能力较强,具有较好的杀菌效果.

  11. 陕北农牧交错带草地面积时空演变与趋势预测%Design and test of a kind of maize ear mechanical drying equipment

    Institute of Scientific and Technical Information of China (English)

    王建洪; 李晶; 任志远

    2011-01-01

    利用1989、2000及2006年3期TM遥感影像,采用遥感技术和地理信息系统相结合的方法,对陕北农牧交错带草地面积的时空演变进行分析.分析表明:从1989年到2000年,由于土地开发利用频繁,草地面积退化较快;从2000年到2006年,草地面积减少得比较缓慢.并利用Markov模型对陕北农牧交错带草地面积的变化情况进行模拟预测,预测表明:陕北农牧交错带草地面积将进一步减少,至2030年,草地面积将减少了21.36万hm2,草地的面积将继续减少.%In order to avoid low efficiency, high crushing rate and expensive operating costs in traditional drying process of maize ear, a kind of mechanical drying equipment was designed. It is simple in structure, easy in unloading and convenient in drying maize at different stages. The equipment was used for drying maize ear in different processes,and the results show that the two-stage drying processes can dry maize ear more efficiently. It can save 21 hours as compared to traditional drying process and the average drying rate was also improved by 42.8 %, operating costs reduced by 36.8%, the maize crushing rate was decreased by 2.2%.

  12. Design analysis of the molten core confinement within the reactor vessel in the case of severe accidents at nuclear power plants equipped with a reactor of the VVER type

    Science.gov (United States)

    Zvonaryov, Yu. A.; Budaev, M. A.; Volchek, A. M.; Gorbaev, V. A.; Zagryazkin, V. N.; Kiselyov, N. P.; Kobzar', V. L.; Konobeev, A. V.; Tsurikov, D. F.

    2013-12-01

    The present paper reports the results of the preliminary design estimate of the behavior of the core melt in vessels of reactors of the VVER-600 and VVER-1300 types (a standard optimized and informative nuclear power unit based on VVER technology—VVER TOI) in the case of beyond-design-basis severe accidents. The basic processes determining the state of the core melt in the reactor vessel are analyzed. The concept of molten core confinement within the vessel based on the idea of outside cooling is discussed. Basic assumptions and models, as well as the results of calculation of the interaction between molten materials of the core and the wall of the reactor vessel performed by means of the SOCRAT severe accident code, are presented and discussed. On the basis of the data obtained, the requirements on the operation of the safety systems are determined, upon the fulfillment of which there will appear potential prerequisites for implementing the concept of the confinement of the core melt within the reactor in cases of severe accidents at nuclear power plants equipped with VVER reactors.

  13. Equipment Operational Requirements

    Energy Technology Data Exchange (ETDEWEB)

    Greenwalt, B; Henderer, B; Hibbard, W; Mercer, M

    2009-06-11

    The Iraq Department of Border Enforcement is rich in personnel, but poor in equipment. An effective border control system must include detection, discrimination, decision, tracking and interdiction, capture, identification, and disposition. An equipment solution that addresses only a part of this will not succeed, likewise equipment by itself is not the answer without considering the personnel and how they would employ the equipment. The solution should take advantage of the existing in-place system and address all of the critical functions. The solutions are envisioned as being implemented in a phased manner, where Solution 1 is followed by Solution 2 and eventually by Solution 3. This allows adequate time for training and gaining operational experience for successively more complex equipment. Detailed descriptions of the components follow the solution descriptions. Solution 1 - This solution is based on changes to CONOPs, and does not have a technology component. It consists of observers at the forts and annexes, forward patrols along the swamp edge, in depth patrols approximately 10 kilometers inland from the swamp, and checkpoints on major roads. Solution 2 - This solution adds a ground sensor array to the Solution 1 system. Solution 3 - This solution is based around installing a radar/video camera system on each fort. It employs the CONOPS from Solution 1, but uses minimal ground sensors deployed only in areas with poor radar/video camera coverage (such as canals and streams shielded by vegetation), or by roads covered by radar but outside the range of the radar associated cameras. This document provides broad operational requirements for major equipment components along with sufficient operational details to allow the technical community to identify potential hardware candidates. Continuing analysis will develop quantities required and more detailed tactics, techniques, and procedures.

  14. Design and development of an anthropomorphic phantom equipped with detectors in order to evaluate the effective dose E at workplaces: feasibility study; Conception et developpement d'un fantome anthropomorphe equipe de detecteurs dans le but d'evaluer la dose efficace a un poste de travail: etude de faisabilite

    Energy Technology Data Exchange (ETDEWEB)

    Furstoss, Ch

    2006-11-15

    My PhD study aims to determine the feasibility to design and develop, for photon fields, an anthropomorphic phantom equipped with detectors in order to evaluate the effective dose E at workplaces. First of all, the energy losses within the organs are calculated using the M.C.N.P.X. Monte Carlo code, in order to determine the detection positions within the different organs. Then, to decrease the number of detection positions, the organ contribution to the effective dose is studied. Finally, the characteristics of the detectors to insert and the characteristics of the phantom to use are deduced. The results show that 24 or 23 detection positions, according to the wT values (publication 60 or new recommendations of the ICRP), give a E estimation with an uncertainty of {+-}15 % from 50 keV to 4 MeV. Moreover, the interest of such an instrument is underlined while comparing the E estimation by the personal dose equivalent Hp to the E estimation by the instrumented phantom when the phantom is irradiated by point sources (worker in front of a glove box for example). Last, after the detector and phantom characteristic determination, two types of detectors and one type of phantom are selected. However, for the detectors mainly, developments are necessary. Follow up this study, the characterization and the adaptation of the detectors to the project would be interesting. Furthermore, the study to mixed photon-neutrons would be required the needs of the radiological protection community. (author)

  15. Resistance welding equipment manufacturing capability for exports

    International Nuclear Information System (INIS)

    Indian Pressurised Heavy Water Reactor (PHWR) fuel bundle is fully welded and is unique in its design. Appendage welding, end closure welding, and end plate welding is carried out using resistance welding technique. Out of many joining processes available, resistance-welding process is reliable, environment friendly and best suitable for mass production applications. Nuclear Fuel Complex (NFC), an industrial unit is established in Hyderabad, under the aegis of the Dept of Atomic Energy to manufacture fuel for Pressurised Heavy Water Reactors. From inception, NFC has given importance for self-reliance and indigenization with respect to manufacturing process and equipment. Sintering furnaces, centreless grinders, appendage-welding machines, end-closure welding equipment and end-plate welding equipments, which were initially imported, are either indigenized or designed and manufactured in house. NFC has designed, manufactured a new appendage-welding machine for manufacturing 37 element fuel bundles. Recently NFC has bagged an order from IAEA through international bidding for design, manufacture, supply, erection and commissioning of end-closure welding equipment. The paper gives in detail the salient features of these welding equipment. (author)

  16. Resistance welding equipment manufacturing capability for exports

    Energy Technology Data Exchange (ETDEWEB)

    Sastry, V.S.; Raju, Y.S.; Somani, A.K.; Setty, D.S.; Rameswara Raw, A.; Hermantha Rao, G.V.S.; Jayaraj, R.N. [Nuclear Fuel Complex, Dept. of Atomic Energy, Hyderbad (India)

    2010-07-01

    Indian Pressurised Heavy Water Reactor (PHWR) fuel bundle is fully welded and is unique in its design. Appendage welding, end closure welding, and end plate welding is carried out using resistance welding technique. Out of many joining processes available, resistance-welding process is reliable, environment friendly and best suitable for mass production applications. Nuclear Fuel Complex (NFC), an industrial unit is established in Hyderabad, under the aegis of the Dept of Atomic Energy to manufacture fuel for Pressurised Heavy Water Reactors. From inception, NFC has given importance for self-reliance and indigenization with respect to manufacturing process and equipment. Sintering furnaces, centreless grinders, appendage-welding machines, end-closure welding equipment and end-plate welding equipments, which were initially imported, are either indigenized or designed and manufactured in house. NFC has designed, manufactured a new appendage-welding machine for manufacturing 37 element fuel bundles. Recently NFC has bagged an order from IAEA through international bidding for design, manufacture, supply, erection and commissioning of end-closure welding equipment. The paper gives in detail the salient features of these welding equipment. (author)

  17. Ag(I), Pb(II) and Hg(II) binding to biomolecules studied by Perturbed Angular Correlation of $\\gamma$-rays (PAC) spectroscopy: Function and toxicity of metal ions in biological systems

    CERN Multimedia

    Metal ions display diverse functions in biological systems and are essential components in both protein structure and function, and in control of biochemical reaction paths and signaling. Similarly, metal ions may be used to control structure and function of synthetic biomolecules, and thus be a tool in the design of molecules with a desired function. In this project we address a variety of questions concerning both the function of metal ions in natural systems, in synthetic biomolecules, and the toxic effect of some metal ions. All projects involve other experimental techniques such as NMR, EXAFS, UV-Vis, fluorescence, and CD spectroscopies providing complementary data, as well as interpretation of the experimental data by quantum mechanical calculations of spectroscopic properties.

  18. MODERNIZATION OF CUPOLA EQUIPMENT

    OpenAIRE

    Rovin, S. L.; L. E. Rovin; T. M. Zayats; L. N. Rusaya

    2015-01-01

    This article presents an automated cupola complex, developed by scientific-production enterprise «Technolit» together with GSTU named after P. O. Sukhoi, launched in the spring of 2015 at the plant «Stroiex» in the city of Chelyabinsk (the Russian Federation). The old cupolas (open type) have been replaced by the new cupolas of the closed type, equipped with automatic control and management system and multistage wet gas treatment system. Cupolas are equipped with systems of post-combustion ga...

  19. Design of Bogie Anti-corrosive Thick Coating Intense Radiation Curing Technology and Equipment%浅析转向架防腐厚涂层强辐射固化工艺及设备设计

    Institute of Scientific and Technical Information of China (English)

    于喜年; 赵月红; 刘军

    2011-01-01

    In order to solve the problem on bogie anti-corrosive thick coating curing,then the thickness of anti-corrosion coating 250 μm or/about and the thickness of general dry film and 5~8 kg limited of scraping putty weight were required in accordance with relevant standards and specifications,as requlated with anti-corrosive thickness.Therefore,the still high quality on welding bogie was proposed and reguested.Analysis of bogie anti-corrosion thick coating paint,curing technology and optimal combination of special anti-corrosive coatings on the surface of high speed bogie was made,which is favourable for tech-equipment and process arrangement and coat infense radiation curing.Short-wave radiation heater is the key component of the coating to be cured.A special combination of structural design by elliptical surface and parabolic surface was adopted.It is more conducive to deep directional radiation which makes the solvent in the bottom of anti-corrosive coating evaporate quickly as a result of strong coating adhesion.Therefore short-wave radiation heater is more suitable for curing the thick coating of wheel axis.Intense radiation curing equipment,parametric design and its virtual assembly provide quick and easy reference in design of anti-corrosive coating curing equipment to produce other relevant products for different manufactures being concerned.%为解决转向架防腐厚涂层固化问题,依照相关标准和规范,对防腐涂层厚度作出规定,要求总干膜厚度为250μm左右,并对腻子的刮涂重量限制在5~8 kg以内,对转向架的焊接质量提出了更高的要求;分析了转向架防腐厚涂层涂覆、固化工艺以及高速动车转向架专用防腐涂料的最优组合,有利于涂层强辐射固化工艺设计和工艺过程安排;短波辐射加热器为涂层固化的关键部件,采用抛物面与椭圆面组合的特殊结构设计,更有利于深层定向辐射,使防腐涂层的底部溶剂迅速挥发,增强了涂层的附

  20. Carbon Absorber Retrofit Equipment (CARE)

    Energy Technology Data Exchange (ETDEWEB)

    Klein, Eric [Neumann Systems Group, Incorporated, Colorado Springs, CO (United States)

    2015-12-23

    During Project DE-FE0007528, CARE (Carbon Absorber Retrofit Equipment), Neumann Systems Group (NSG) designed, installed and tested a 0.5MW NeuStream® carbon dioxide (CO2) capture system using the patented NeuStream® absorber equipment and concentrated (6 molal) piperazine (PZ) as the solvent at Colorado Springs Utilities’ (CSU’s) Martin Drake pulverized coal (PC) power plant. The 36 month project included design, build and test phases. The 0.5MW NeuStream® CO2 capture system was successfully tested on flue gas from both coal and natural gas combustion sources and was shown to meet project objectives. Ninety percent CO2 removal was achieved with greater than 95% CO2product purity. The absorbers tested support a 90% reduction in absorber volume compared to packed towers and with an absorber parasitic power of less than 1% when configured for operation with a 550MW coal plant. The preliminary techno-economic analysis (TEA) performed by the Energy and Environmental Research Center (EERC) predicted an over-the-fence cost of $25.73/tonne of CO2 captured from a sub-critical PC plant.