Roehner, Nicholas; Zhang, Zhen; Nguyen, Tramy; Myers, Chris J
In the context of synthetic biology, model generation is the automated process of constructing biochemical models based on genetic designs. This paper discusses the use cases for model generation in genetic design automation (GDA) software tools and introduces the foundational concepts of standards and model annotation that make this process useful. Finally, this paper presents an implementation of model generation in the GDA software tool iBioSim and provides an example of generating a Systems Biology Markup Language (SBML) model from a design of a 4-input AND sensor written in the Synthetic Biology Open Language (SBOL).
Online & CD-ROM Review, 1997
In 1996 a working group of the World Wide Web Consortium developed and released a simpler form of markup language, Extensible Markup Language (XML), combining the flexibility of standard Generalized Markup Language (SGML) and the Web suitability of HyperText Markup Language (HTML). Reviews SGML and discusses XML's suitability for journal…
Hucka, Michael; Bergmann, Frank T; Hoops, Stefan; Keating, Sarah M; Sahle, Sven; Schaff, James C; Smith, Lucian P; Wilkinson, Darren J
Computational models can help researchers to interpret data, understand biological function, and make quantitative predictions. The Systems Biology Markup Language (SBML) is a file format for representing computational models in a declarative form that can be exchanged between different software systems. SBML is oriented towards describing biological processes of the sort common in research on a number of topics, including metabolic pathways, cell signaling pathways, and many others. By supporting SBML as an input/output format, different tools can all operate on an identical representation of a model, removing opportunities for translation errors and assuring a common starting point for analyses and simulations. This document provides the specification for Version 1 of SBML Level 3 Core. The specification defines the data structures prescribed by SBML as well as their encoding in XML, the eXtensible Markup Language. This specification also defines validation rules that determine the validity of an SBML document, and provides many examples of models in SBML form. Other materials and software are available from the SBML project web site, http://sbml.org/.
Full Text Available Computational models can help researchers to interpret data, understand biological functions, and make quantitative predictions. The Systems Biology Markup Language (SBML is a file format for representing computational models in a declarative form that different software systems can exchange. SBML is oriented towards describing biological processes of the sort common in research on a number of topics, including metabolic pathways, cell signaling pathways, and many others. By supporting SBML as an input/output format, different tools can all operate on an identical representation of a model, removing opportunities for translation errors and assuring a common starting point for analyses and simulations. This document provides the specification for Release 2 of Version 1 of SBML Level 3 Core. The specification defines the data structures prescribed by SBML, their encoding in XML (the eXtensible Markup Language, validation rules that determine the validity of an SBML document, and examples of models in SBML form. No design changes have been made to the description of models between Release 1 and Release 2; changes are restricted to the format of annotations, the correction of errata and the addition of clarifications. Other materials and software are available from the SBML project website at http://sbml.org/.
Zi, Zhike; Zheng, Yanan; Rundell, Ann E; Klipp, Edda
It has long been recognized that sensitivity analysis plays a key role in modeling and analyzing cellular and biochemical processes. Systems biology markup language (SBML) has become a well-known platform for coding and sharing mathematical models of such processes. However, current SBML compatible software tools are limited in their ability to perform global sensitivity analyses of these models. This work introduces a freely downloadable, software package, SBML-SAT, which implements algorithms for simulation, steady state analysis, robustness analysis and local and global sensitivity analysis for SBML models. This software tool extends current capabilities through its execution of global sensitivity analyses using multi-parametric sensitivity analysis, partial rank correlation coefficient, SOBOL's method, and weighted average of local sensitivity analyses in addition to its ability to handle systems with discontinuous events and intuitive graphical user interface. SBML-SAT provides the community of systems biologists a new tool for the analysis of their SBML models of biochemical and cellular processes.
Gauges, Ralph; Rost, Ursula; Sahle, Sven; Wengler, Katja; Bergmann, Frank Thomas
Many software tools provide facilities for depicting reaction network diagrams in a visual form. Two aspects of such a visual diagram can be distinguished: the layout (i.e.: the positioning and connections) of the elements in the diagram, and the graphical form of the elements (for example, the glyphs used for symbols, the properties of the lines connecting them, and so on). For software tools that also read and write models in SBML (Systems Biology Markup Language) format, a common need is to store the network diagram together with the SBML representation of the model. This in turn raises the question of how to encode the layout and the rendering of these diagrams. The SBML Level 3 Version 1 Core specification does not provide a mechanism for explicitly encoding diagrams, but it does provide a mechanism for SBML packages to extend the Core specification and add additional syntactical constructs. The Layout package for SBML Level 3 adds the necessary features to SBML so that diagram layouts can be encoded in SBML files, and a companion package called SBML Rendering specifies how the graphical rendering of elements can be encoded. The SBML Layout package is based on the principle that reaction network diagrams should be described as representations of entities such as species and reactions (with direct links to the underlying SBML elements), and not as arbitrary drawings or graphs; for this reason, existing languages for the description of vector drawings (such as SVG) or general graphs (such as GraphML) cannot be used.
Watanabe, Leandro; Myers, Chris J
The Systems Biology Markup Language (SBML) has been widely used for modeling biological systems. Although SBML has been successful in representing a wide variety of biochemical models, the core standard lacks the structure for representing large complex regular systems in a standard way, such as whole-cell and cellular population models. These models require a large number of variables to represent certain aspects of these types of models, such as the chromosome in the whole-cell model and the many identical cell models in a cellular population. While SBML core is not designed to handle these types of models efficiently, the proposed SBML arrays package can represent such regular structures more easily. However, in order to take full advantage of the package, analysis needs to be aware of the arrays structure. When expanding the array constructs within a model, some of the advantages of using arrays are lost. This paper describes a more efficient way to simulate arrayed models. To illustrate the proposed method, this paper uses a population of repressilator and genetic toggle switch circuits as examples. Results show that there are memory benefits using this approach with a modest cost in runtime.
Lassila, O; van Harmelen, F; Horrocks, I.; Hendler, J.; McGuinness, DL
The DARPA Agent Markup Language (DAML) program is a United States government sponsored endeavor aimed at providing the foundation for the next web evolution – the semantic web. The program is funding critical research to develop languages, tools and techniques for making considerably more of the
Beltrame, Luca; Calura, Enrica; Popovici, Razvan R; Rizzetto, Lisa; Guedez, Damariz Rivero; Donato, Michele; Romualdi, Chiara; Draghici, Sorin; Cavalieri, Duccio
Many models and analysis of signaling pathways have been proposed. However, neither of them takes into account that a biological pathway is not a fixed system, but instead it depends on the organism, tissue and cell type as well as on physiological, pathological and experimental conditions. The Biological Connection Markup Language (BCML) is a format to describe, annotate and visualize pathways. BCML is able to store multiple information, permitting a selective view of the pathway as it exists and/or behave in specific organisms, tissues and cells. Furthermore, BCML can be automatically converted into data formats suitable for analysis and into a fully SBGN-compliant graphical representation, making it an important tool that can be used by both computational biologists and 'wet lab' scientists. The XML schema and the BCML software suite are freely available under the LGPL for download at http://bcml.dc-atlas.net. They are implemented in Java and supported on MS Windows, Linux and OS X.
Goldbaum, Jesse M.
The Astronomical Instrumentation System Markup Language (AISML) is an Extensible Markup Language (XML) based file format for maintaining and exchanging information about astronomical instrumentation. The factors behind the need for an AISML are first discussed followed by the reasons why XML was chosen as the format. Next it's shown how XML also provides the framework for a more precise definition of an astronomical instrument and how these instruments can be combined to form an Astronomical Instrumentation System (AIS). AISML files for several instruments as well as one for a sample AIS are provided. The files demonstrate how AISML can be utilized for various tasks from web page generation and programming interface to instrument maintenance and quality management. The advantages of widespread adoption of AISML are discussed.
Currently, a lot of effort is being put on designing complex detectors. A number of simulation and reconstruction frameworks and applications have been developed with the aim to make this job easier. A very important role in this activity is played by the geometry description of the detector apparatus layout and its working environment. However, no real common approach to represent geometry data is available and such data can be found in various forms starting from custom semi-structured text files, source code (C/C++/FORTRAN), to XML and database solutions. The XML (Extensible Markup Language) has proven to provide an interesting approach for describing detector geometries, with several different but incompatible XML-based solutions existing. Therefore, interoperability and geometry data exchange among different frameworks is not possible at present. The author introduces a markup language for geometry descriptions. Its aim is to define a common approach for sharing and exchanging of geometry description data. Its requirements and design have been driven by experience and user feedback from existing projects which have their geometry description in XML
2-4 Figure 2-5. Common Name and Location Definitions ........................................................... 2-4 Data Display Markup Language ...DOM document object model DTD document type definition IRIG Inter-range Instrumentation Group MathML Mathematical Markup Language RCC Range...Moreover, the tendency of T&E is towards a plug-and-play-like data acquisition system that requires standard languages and modules for data displays
Varde, Aparna; Rundensteiner, Elke; Fahrenholz, Sally
A challenging area in web based support systems is the study of human activities in connection with the web, especially with reference to certain domains. This includes capturing human reasoning in information retrieval, facilitating the exchange of domain-specific knowledge through a common platform and developing tools for the analysis of data on the web from a domain expert's angle. Among the techniques and standards related to such work, we have XML, the eXtensible Markup Language. This serves as a medium of communication for storing and publishing textual, numeric and other forms of data seamlessly. XML tag sets are such that they preserve semantics and simplify the understanding of stored information by users. Often domain-specific markup languages are designed using XML, with a user-centric perspective. Standardization bodies and research communities may extend these to include additional semantics of areas within and related to the domain. This chapter outlines the issues to be considered in developing domain-specific markup languages: the motivation for development, the semantic considerations, the syntactic constraints and other relevant aspects, especially taking into account human factors. Illustrating examples are provided from domains such as Medicine, Finance and Materials Science. Particular emphasis in these examples is on the Materials Markup Language MatML and the semantics of one of its areas, namely, the Heat Treating of Materials. The focus of this chapter, however, is not the design of one particular language but rather the generic issues concerning the development of domain-specific markup languages.
Describes Extensible Markup Language (XML), a subset of the Standard Generalized Markup Language (SGML) that is designed to make it easy to interchange structured documents over the Internet. Topics include Document Type Definition (DTD), components of XML, the use of XML, text and non-text elements, and uses for XML-coded files. (LRW)
Full Text Available The paper discusses the role of descriptive markup languages in the development of digital humanities, a new research discipline that is part of social sciences and humanities, which focuses on the use of computers in research. A chronological review of the development of digital humanities, and then descriptive markup languages is exposed, through several developmental stages. It is shown that the development of digital humanities since the mid-1980s and the appearance of SGML, markup language that was the foundation of TEI, a key standard for the encoding and exchange of humanities texts in the digital environment, is inseparable from the development of markup languages. Special attention is dedicated to the presentation of the Text Encoding Initiative – TEI development, a key organization that developed the titled standard, both from organizational and markup perspectives. By this time, TEI standard is published in five versions, and during 2000s SGML is replaced by XML markup language. Key words: markup languages, digital humanities, text encoding, TEI, SGML, XML
Loia, Vincenzo; Lee, Chang-Shing; Wang, Mei-Hui
One of the most successful methodology that arose from the worldwide diffusion of Fuzzy Logic is Fuzzy Control. After the first attempts dated in the seventies, this methodology has been widely exploited for controlling many industrial components and systems. At the same time, and very independently from Fuzzy Logic or Fuzzy Control, the birth of the Web has impacted upon almost all aspects of computing discipline. Evolution of Web, Web 2.0 and Web 3.0 has been making scenarios of ubiquitous computing much more feasible; consequently information technology has been thoroughly integrated into everyday objects and activities. What happens when Fuzzy Logic meets Web technology? Interesting results might come out, as you will discover in this book. Fuzzy Mark-up Language is a son of this synergistic view, where some technological issues of Web are re-interpreted taking into account the transparent notion of Fuzzy Control, as discussed here. The concept of a Fuzzy Control that is conceived and modeled in terms...
Saadawi, Gilan M; Harrison, James H
Clinical laboratory procedure manuals are typically maintained as word processor files and are inefficient to store and search, require substantial effort for review and updating, and integrate poorly with other laboratory information. Electronic document management systems could improve procedure management and utility. As a first step toward building such systems, we have developed a prototype electronic format for laboratory procedures using Extensible Markup Language (XML). Representative laboratory procedures were analyzed to identify document structure and data elements. This information was used to create a markup vocabulary, CLP-ML, expressed as an XML Document Type Definition (DTD). To determine whether this markup provided advantages over generic markup, we compared procedures structured with CLP-ML or with the vocabulary of the Health Level Seven, Inc. (HL7) Clinical Document Architecture (CDA) narrative block. CLP-ML includes 124 XML tags and supports a variety of procedure types across different laboratory sections. When compared with a general-purpose markup vocabulary (CDA narrative block), CLP-ML documents were easier to edit and read, less complex structurally, and simpler to traverse for searching and retrieval. In combination with appropriate software, CLP-ML is designed to support electronic authoring, reviewing, distributing, and searching of clinical laboratory procedures from a central repository, decreasing procedure maintenance effort and increasing the utility of procedure information. A standard electronic procedure format could also allow laboratories and vendors to share procedures and procedure layouts, minimizing duplicative word processor editing. Our results suggest that laboratory-specific markup such as CLP-ML will provide greater benefit for such systems than generic markup.
Franke, K.Y.; Guyon, I.; Schomaker, L.R.B.; Vuurpijl, L.G.
WANDAML is an XML-based markup language for the annotation and filter journaling of digital documents. It addresses in particular the needs of forensic handwriting data examination, by allowing experts to enter information about writer, material (pen, paper), script and content, and to record chains
Franke, K.; Guyon, I.; Schomaker, L.; Vuurpijl, L.
WANDAML is an XML-based markup language for the annotation and filter journaling of digital documents. It addresses in particular the needs of forensic handwriting data examination, by allowing experts to enter information about writer, material (pen, paper), script and content, and to record chains
Full Text Available Data and information exchange are crucial for any kind of scientific research activities and are becoming more and more important. The comparison between different data sets and different disciplines creates new data, adds value, and finally accumulates knowledge. Also the distribution and accessibility of research results is an important factor for international work. The gas hydrate research community is dispersed across the globe and therefore, a common technical communication language or format is strongly demanded. The CODATA Gas Hydrate Data Task Group is creating the Gas Hydrate Markup Language (GHML, a standard based on the Extensible Markup Language (XML to enable the transport, modeling, and storage of all manner of objects related to gas hydrate research. GHML initially offers an easily deducible content because of the text-based encoding of information, which does not use binary data. The result of these investigations is a custom-designed application schema, which describes the features, elements, and their properties, defining all aspects of Gas Hydrates. One of the components of GHML is the "Field Data" module, which is used for all data and information coming from the field. It considers international standards, particularly the standards defined by the W3C (World Wide Web Consortium and the OGC (Open Geospatial Consortium. Various related standards were analyzed and compared with our requirements (in particular the Geographic Markup Language (ISO19136, GML and the whole ISO19000 series. However, the requirements demanded a quick solution and an XML application schema readable for any scientist without a background in information technology. Therefore, ideas, concepts and definitions have been used to build up the modules of GHML without importing any of these Markup languages. This enables a comprehensive schema and simple use.
Full Text Available Natural gas hydrates, as an important potential fuels, flow assurance hazards, and possible factors initiating the submarine geo-hazard and global climate change, have attracted the interest of scientists all over the world. After two centuries of hydrate research, a great amount of scientific data on gas hydrates has been accumulated. Therefore the means to manage, share, and exchange these data have become an urgent task. At present, metadata (Markup Language is recognized as one of the most efficient ways to facilitate data management, storage, integration, exchange, discovery and retrieval. Therefore the CODATA Gas Hydrate Data Task Group proposed and specified Gas Hydrate Markup Language (GHML as an extensible conceptual metadata model to characterize the features of data on gas hydrate. This article introduces the details of modeling portion of GHML.
Sagan, D.; Forster, M.; /Cornell U., LNS; Bates, D.A.; /LBL, Berkeley; Wolski, A.; /Liverpool U. /Cockcroft Inst. Accel. Sci. Tech.; Schmidt, F.; /CERN; Walker, N.J.; /DESY; Larrieu, T.; Roblin, Y.; /Jefferson Lab; Pelaia, T.; /Oak Ridge; Tenenbaum, P.; Woodley, M.; /SLAC; Reiche, S.; /UCLA
A major obstacle to collaboration on accelerator projects has been the sharing of lattice description files between modeling codes. To address this problem, a lattice description format called Accelerator Markup Language (AML) has been created. AML is based upon the standard eXtensible Markup Language (XML) format; this provides the flexibility for AML to be easily extended to satisfy changing requirements. In conjunction with AML, a software library, called the Universal Accelerator Parser (UAP), is being developed to speed the integration of AML into any program. The UAP is structured to make it relatively straightforward (by giving appropriate specifications) to read and write lattice files in any format. This will allow programs that use the UAP code to read a variety of different file formats. Additionally, this will greatly simplify conversion of files from one format to another. Currently, besides AML, the UAP supports the MAD lattice format.
Sall, Ken; Ames, Troy; Warsaw, Craig; Koons, Lisa; Shafer, Richard
The Instrument Remote Control (IRC) project ongoing at NASA's Goddard Space Flight Center's (GSFC) Information Systems Center (ISC) supports NASA's mission by defining an adaptive intranet-based framework that provides robust interactive and distributed control and monitoring of remote instruments. An astronomical IRC architecture that combines the platform-independent processing capabilities of Java with the power of Extensible Markup Language (XML) to express hierarchical data in an equally platform-independent, as well as human readable manner, has been developed. This architecture is implemented using a variety of XML support tools and Application Programming Interfaces (API) written in Java. IRC will enable trusted astronomers from around the world to easily access infrared instruments (e.g., telescopes, cameras, and spectrometers) located in remote, inhospitable environments, such as the South Pole, a high Chilean mountaintop, or an airborne observatory aboard a Boeing 747. Using IRC's frameworks, an astronomer or other scientist can easily define the type of onboard instrument, control the instrument remotely, and return monitoring data all through the intranet. The Astronomical Instrument Markup Language (AIML) is the first implementation of the more general Instrument Markup Language (IML). The key aspects of our approach to instrument description and control applies to many domains, from medical instruments to machine assembly lines. The concepts behind AIML apply equally well to the description and control of instruments in general. IRC enables us to apply our techniques to several instruments, preferably from different observatories.
Lansdowne, Chatwin A.; McCartney, Patrick; Gorringe, Chris
The authors describe challenging use-cases for Automatic Test Markup Language (ATML), and evaluate solutions. The first case uses ATML Test Results to deliver active features to support test procedure development and test flow, and bridging mixed software development environments. The second case examines adding attributes to Systems Modelling Language (SysML) to create a linkage for deriving information from a model to fill in an ATML document set. Both cases are outside the original concept of operations for ATML but are typical when integrating large heterogeneous systems with modular contributions from multiple disciplines.
...-S), the Web Ontology Query Language (OWL-QL) and Semantic Web Rule Language (SWRL) W3C submissions. This report contains the evolution of these markup languages as well as a discussion of semantic query languages, proof and explanation...
Wernecke, J.; Bailey, J. E.
The development of virtual globes has provided a fun and innovative tool for exploring the surface of the Earth. However, it has been the paralleling maturation of Keyhole Markup Language (KML) that has created a new medium and perspective through which to visualize scientific datasets. Originally created by Keyhole Inc., and then acquired by Google in 2004, in 2007 KML was given over to the Open Geospatial Consortium (OGC). It became an OGC international standard on 14 April 2008, and has subsequently been adopted by all major geobrowser developers (e.g., Google, Microsoft, ESRI, NASA) and many smaller ones (e.g., Earthbrowser). By making KML a standard at a relatively young stage in its evolution, developers of the language are seeking to avoid the issues that plagued the early World Wide Web and development of Hypertext Markup Language (HTML). The popularity and utility of Google Earth, in particular, has been enhanced by KML features such as the Smithsonian volcano layer and the dynamic weather layers. Through KML, users can view real-time earthquake locations (USGS), view animations of polar sea-ice coverage (NSIDC), or read about the daily activities of chimpanzees (Jane Goodall Institute). Perhaps even more powerful is the fact that any users can create, edit, and share their own KML, with no or relatively little knowledge of manipulating computer code. We present an overview of the best current scientific uses of KML and a guide to how scientists can learn to use KML themselves.
Qin, X.; Müller, R. D.; Cannon, J.; Landgrebe, T. C. W.; Heine, C.; Watson, R. J.; Turner, M.
Understanding tectonic and geodynamic processes leading to the present-day configuration of the Earth involves studying data and models across a variety of disciplines, from geochemistry, geochronology and geophysics, to plate kinematics and mantle dynamics. All these data represent a 3-D spatial and 1-D temporal framework, a formalism which is not exploited by traditional spatial analysis tools. This is arguably a fundamental limit in both the rigour and sophistication in which datasets can be combined for geological deep time analysis, and often confines the extent of data analyses to the present-day configurations of geological objects. The GPlates Geological Information Model (GPGIM) represents a formal specification of geological and geophysical data in a time-varying plate tectonics context, used by the GPlates virtual-globe software. It provides a framework in which relevant types of geological data are attached to a common plate tectonic reference frame, allowing the data to be reconstructed in a time-dependent spatio-temporal plate reference frame. The GPlates Markup Language (GPML), being an extension of the open standard Geography Markup Language (GML), is both the modelling language for the GPGIM and an XML-based data format for the interoperable storage and exchange of data modelled by it. The GPlates software implements the GPGIM allowing researchers to query, visualise, reconstruct and analyse a rich set of geological data including numerical raster data. The GPGIM has recently been extended to support time-dependent geo-referenced numerical raster data by wrapping GML primitives into the time-dependent framework of the GPGIM. Coupled with GPlates' ability to reconstruct numerical raster data and import/export from/to a variety of raster file formats, as well as its handling of time-dependent plate boundary topologies, interoperability with geodynamic softwares is established, leading to a new generation of deep-time spatio-temporal data analysis and
Valcic, L.; Bailey, J. E.; Dehn, J.
Over the last five years there has been a proliferation in the development of virtual globe programs. Programs such as Google Earth, NASA World Wind, SkylineGlobe, Geofusion and ArcGIS Explorer each have their own strengths and weaknesses, and whether a market will remain for all tools will be determined by user application. This market is currently led by Google Earth, the release of which on 28 Jun 2005 helped spark a revolution in virtual globe technology, by bringing it into the public view and imagination. Many would argue that such a revolution was due, but it was certainly aided by the world-wide name recognition of Google, and the creation of a user-friendly interface. Google Earth is an updated version of a program originally called Earth Viewer, which was developed by Keyhole Inc. It was renamed after Google purchased Keyhole and their technology in 2001. In order to manage the geospatial data within these viewers, the developers created a new XML-based (Extensible Markup Language) called Keyhole Markup Language (KML). Through manipulation of KML scientists are finding increasingly creative and more visually appealing methods to display and manipulate their data. A measure of the success of Google Earth and KML is demonstrated by the fact that other virtual globes are now including various levels of KML compatibility. This presentation will display examples of how KML has been applied to scientific data. It will offer a forum for questions pertaining to how KML can be applied to a user's dataset. Interested parties are encouraged to bring examples of projects under development or being planned.
Jung, Won-Mo; Chae, Younbyoung; Jang, Bo-Hyoung
Nowadays a lot of trials for collecting electronic medical records (EMRs) exist. However, structuring data format for EMR is an especially labour-intensive task for practitioners. Here we propose a new mark-up language for medical record charting (called Charting Language), which borrows useful properties from programming languages. Thus, with Charting Language, the text data described in dynamic situation can be easily used to extract information.
Full Text Available Understanding tectonic and geodynamic processes leading to the present-day configuration of the Earth involves studying data and models across a variety of disciplines, from geochemistry, geochronology and geophysics, to plate kinematics and mantle dynamics. All these data represent a 3-D spatial and 1-D temporal framework, a formalism which is not exploited by traditional spatial analysis tools. This is arguably a fundamental limit in both the rigour and sophistication in which datasets can be combined for geological deep time analysis, and often confines the extent of data analyses to the present-day configurations of geological objects. The GPlates Geological Information Model (GPGIM represents a formal specification of geological and geophysical data in a time-varying plate tectonics context, used by the GPlates virtual-globe software. It provides a framework in which relevant types of geological data are attached to a common plate tectonic reference frame, allowing the data to be reconstructed in a time-dependent spatio-temporal plate reference frame. The GPlates Markup Language (GPML, being an extension of the open standard Geography Markup Language (GML, is both the modelling language for the GPGIM and an XML-based data format for the interoperable storage and exchange of data modelled by it. The GPlates software implements the GPGIM allowing researchers to query, visualise, reconstruct and analyse a rich set of geological data including numerical raster data. The GPGIM has recently been extended to support time-dependent geo-referenced numerical raster data by wrapping GML primitives into the time-dependent framework of the GPGIM. Coupled with GPlates' ability to reconstruct numerical raster data and import/export from/to a variety of raster file formats, as well as its handling of time-dependent plate boundary topologies, interoperability with geodynamic softwares is established, leading to a new generation of deep-time spatio
Brian, Geoffrey J.; Jackson, E. Bruce
The Dynamic Aerospace Vehicle Exchange Markup Language (DAVE-ML) is a syntactical language for exchanging flight vehicle dynamic model data. It provides a framework for encoding entire flight vehicle dynamic model data packages for exchange and/or long-term archiving. Version 2.0.1 of DAVE-ML provides much of the functionality envisioned for exchanging aerospace vehicle data; however, it is limited in only supporting scalar time-independent data. Additional functionality is required to support vector and matrix data, abstracting sub-system models, detailing dynamics system models (both discrete and continuous), and defining a dynamic data format (such as time sequenced data) for validation of dynamics system models and vehicle simulation packages. Extensions to DAVE-ML have been proposed to manage data as vectors and n-dimensional matrices, and record dynamic data in a compatible form. These capabilities will improve the clarity of data being exchanged, simplify the naming of parameters, and permit static and dynamic data to be stored using a common syntax within a single file; thereby enhancing the framework provided by DAVE-ML for exchanging entire flight vehicle dynamic simulation models.
Full Text Available CrossRef is an association of scholarly publishers that develops shared infrastructure to support more effective scholarly communications. Launched in 2000, CrossRef’s citation-linking network today covers over 68 million journal articles and other content items (books chapters, data, theses, and technical reports from thousands of scholarly and professional publishers around the globe. CrossRef has over 4,000 member publishers who join as members in order to avail of a number of CrossRef services, reference linking via the Digital Object Identifier (DOI being the core service. To deposit CrossRef DOIs, publishers and editors need to become familiar with the basics of extensible markup language (XML. This article will give an introduction to CrossRef XML and what publishers need to do in order to start to deposit DOIs with CrossRef and thus ensure their publications are discoverable and can be linked to consistently in an online environment.
Leif, Robert C.; Leif, Stephanie H.; Leif, Suzanne B.
Cytometry Markup Language, CytometryML, is a proposed new analytical cytology data standard. CytometryML is a set of XML schemas for encoding both flow cytometry and digital microscopy text based data types. CytometryML schemas reference both DICOM (Digital Imaging and Communications in Medicine) codes and FCS keywords. These schemas provide representations for the keywords in FCS 3.0 and will soon include DICOM microscopic image data. Flow Cytometry Standard (FCS) list-mode has been mapped to the DICOM Waveform Information Object. A preliminary version of a list mode binary data type, which does not presently exist in DICOM, has been designed. This binary type is required to enhance the storage and transmission of flow cytometry and digital microscopy data. Index files based on Waveform indices will be used to rapidly locate the cells present in individual subsets. DICOM has the advantage of employing standard file types, TIF and JPEG, for Digital Microscopy. Using an XML schema based representation means that standard commercial software packages such as Excel and MathCad can be used to analyze, display, and store analytical cytometry data. Furthermore, by providing one standard for both DICOM data and analytical cytology data, it eliminates the need to create and maintain special purpose interfaces for analytical cytology data thereby integrating the data into the larger DICOM and other clinical communities. A draft version of CytometryML is available at www.newportinstruments.com.
Bergmann, Frank T; Cooper, Jonathan; König, Matthias; Moraru, Ion; Nickerson, David; Le Novère, Nicolas; Olivier, Brett G; Sahle, Sven; Smith, Lucian; Waltemath, Dagmar
The creation of computational simulation experiments to inform modern biological research poses challenges to reproduce, annotate, archive, and share such experiments. Efforts such as SBML or CellML standardize the formal representation of computational models in various areas of biology. The Simulation Experiment Description Markup Language (SED-ML) describes what procedures the models are subjected to, and the details of those procedures. These standards, together with further COMBINE standards, describe models sufficiently well for the reproduction of simulation studies among users and software tools. The Simulation Experiment Description Markup Language (SED-ML) is an XML-based format that encodes, for a given simulation experiment, (i) which models to use; (ii) which modifications to apply to models before simulation; (iii) which simulation procedures to run on each model; (iv) how to post-process the data; and (v) how these results should be plotted and reported. SED-ML Level 1 Version 1 (L1V1) implemented support for the encoding of basic time course simulations. SED-ML L1V2 added support for more complex types of simulations, specifically repeated tasks and chained simulation procedures. SED-ML L1V3 extends L1V2 by means to describe which datasets and subsets thereof to use within a simulation experiment.
Full Text Available Artificial intelligence technology nowadays, can be processed with a variety of forms, such as chatbot, and the various methods, one of them using Artificial Intelligence Markup Language (AIML. AIML using template matching, by comparing the specific patterns in the database. AIML template design process begins with determining the necessary information, then formed into questions, these questions adapted to AIML pattern. From the results of the study, can be known that the Question-Answering System in the chatbot using Artificial Intelligence Markup Language are able to communicate and deliver information. Keywords: Artificial Intelligence, Template Matching, Artificial Intelligence Markup Language, AIML Teknologi kecerdasan buatan saat ini dapat diolah dengan berbagai macam bentuk, seperti ChatBot, dan berbagai macam metode, salah satunya menggunakan Artificial Intelligence Markup Language (AIML. AIML menggunakan metode template matching yaitu dengan membandingkan pola-pola tertentu pada database. Proses perancangan template AIML diawali dengan menentukan informasi yang diperlukan, kemudian dibentuk menjadi pertanyaan, pertanyaan tersebut disesuaikan dengan bentuk pattern AIML. Hasil penelitian dapat diperoleh bahwa Question-Answering System dalam bentuk ChatBot menggunakan Artificial Intelligence Markup Language dapat berkomunikasi dan menyampaikan informasi. Kata kunci : Kecerdasan Buatan, Pencocokan Pola, Artificial Intelligence Markup Language, AIML
Today's modern aerospace systems exhibit strong interdisciplinary coupling and require a multidisciplinary, collaborative approach. Analysis methods that were once considered feasible only for advanced and detailed design are now available and even practical at the conceptual design stage. This changing philosophy for conducting conceptual design poses additional challenges beyond those encountered in a low fidelity design of aircraft. This thesis takes some steps towards bridging the gaps in existing technologies and advancing the state-of-the-art in aircraft design. The first part of the thesis proposes a new Pareto front approximation method for multiobjective optimization problems. The method employs a hybrid optimization approach using two derivative free direct search techniques, and is intended for solving blackbox simulation based multiobjective optimization problems with possibly nonsmooth functions where the analytical formof the objectives is not known and/or the evaluation of the objective function(s) is very expensive (very common in multidisciplinary design optimization). A new adaptive weighting scheme is proposed to convert a multiobjective optimization problem to a single objective optimization problem. Results show that the method achieves an arbitrarily close approximation to the Pareto front with a good collection of well-distributed nondominated points. The second part deals with the interdisciplinary data communication issues involved in a collaborative mutidisciplinary aircraft design environment. Efficient transfer, sharing, and manipulation of design and analysis data in a collaborative environment demands a formal structured representation of data. XML, a W3C recommendation, is one such standard concomitant with a number of powerful capabilities that alleviate interoperability issues. A compact, generic, and comprehensive XML schema for an aircraft design markup language (ADML) is proposed here to provide a common language for data
Chen, Yih-Feng; Kuo, May-Chen; Sun, Xiaoming; Kuo, C.-C. Jay
An object-oriented methodology is proposed to harmonize several different markup languages in this research. First, we adopt the Unified Modelling Language (UML) as the data model to formalize the concept and the process of the harmonization process between the eXtensible Markup Language (XML) applications. Then, we design the Harmonization eXtensible Markup Language (HXML) based on the data model and formalize the transformation between the Document Type Definitions (DTDs) of the original XML applications and HXML. The transformation between instances is also discussed. We use the harmonization of SMIL and X3D as an example to demonstrate the proposed methodology. This methodology can be generalized to various application domains.
Manion Frank J
Full Text Available Abstract Background Flow cytometry technology is widely used in both health care and research. The rapid expansion of flow cytometry applications has outpaced the development of data storage and analysis tools. Collaborative efforts being taken to eliminate this gap include building common vocabularies and ontologies, designing generic data models, and defining data exchange formats. The Minimum Information about a Flow Cytometry Experiment (MIFlowCyt standard was recently adopted by the International Society for Advancement of Cytometry. This standard guides researchers on the information that should be included in peer reviewed publications, but it is insufficient for data exchange and integration between computational systems. The Functional Genomics Experiment (FuGE formalizes common aspects of comprehensive and high throughput experiments across different biological technologies. We have extended FuGE object model to accommodate flow cytometry data and metadata. Methods We used the MagicDraw modelling tool to design a UML model (Flow-OM according to the FuGE extension guidelines and the AndroMDA toolkit to transform the model to a markup language (Flow-ML. We mapped each MIFlowCyt term to either an existing FuGE class or to a new FuGEFlow class. The development environment was validated by comparing the official FuGE XSD to the schema we generated from the FuGE object model using our configuration. After the Flow-OM model was completed, the final version of the Flow-ML was generated and validated against an example MIFlowCyt compliant experiment description. Results The extension of FuGE for flow cytometry has resulted in a generic FuGE-compliant data model (FuGEFlow, which accommodates and links together all information required by MIFlowCyt. The FuGEFlow model can be used to build software and databases using FuGE software toolkits to facilitate automated exchange and manipulation of potentially large flow cytometry experimental data sets
This document provides the guidance necessary to transmit to DOE's Office of Scientific and Technical Information (OSTI) an encoded bibliographic record that conforms to International Standard ISO 8879, Information Processing -- Text and office systems -- Standard Generalized Markup Language (SGML). Included in this document are element and attribute tag definitions, sample bibliographic records, the bibliographic document type definition, and instructions on how to transmit a bibliographic record electronically to OSTI
This document provides the guidance necessary to transmit to DOE`s Office of Scientific and Technical Information (OSTI) an encoded bibliographic record that conforms to International Standard ISO 8879, Information Processing -- Text and office systems -- Standard Generalized Markup Language (SGML). Included in this document are element and attribute tag definitions, sample bibliographic records, the bibliographic document type definition, and instructions on how to transmit a bibliographic record electronically to OSTI.
Babaie, H.; Babaei, A.
The Extensible Markup Language (XML) and its specifications such as the XSD Schema, allow geologists to design discipline-specific vocabularies such as Seismology Markup Language (SeismML) or Plate Tectonics Markup Language (TectML). These languages make it possible to store and interchange structured geological information over the Web. Development of a geological markup language requires mapping geological concepts, such as "Earthquake" or "Plate" into a UML object model, applying a modeling and design environment. We have selected four inter-related geological concepts: earthquake, fault, plate, and orogeny, and developed four XML Schema Definitions (XSD), that define the relationships, cardinalities, hierarchies, and semantics of these concepts. In such a geological concept model, the UML object "Earthquake" is related to one or more "Wave" objects, each arriving to a seismic station at a specific "DateTime", and relating to a specific "Epicenter" object that lies at a unique "Location". The "Earthquake" object occurs along a "Segment" of a "Fault" object, which is related to a specific "Plate" object. The "Fault" has its own associations with such things as "Bend", "Step", and "Segment", and could be of any kind (e.g., "Thrust", "Transform'). The "Plate" is related to many other objects such as "MOR", "Subduction", and "Forearc", and is associated with an "Orogeny" object that relates to "Deformation" and "Strain" and several other objects. These UML objects were mapped into XML Metadata Interchange (XMI) formats, which were then converted into four XSD Schemas. The schemas were used to create and validate the XML instance documents, and to create a relational database hosting the plate tectonics and seismological data in the Microsoft Access format. The SeismML and TectML allow seismologists and structural geologists, among others, to submit and retrieve structured geological data on the Internet. A seismologist, for example, can submit peer-reviewed and
Lobet, Guillaume; Pound, Michael P; Diener, Julien; Pradal, Christophe; Draye, Xavier; Godin, Christophe; Javaux, Mathieu; Leitner, Daniel; Meunier, Félicien; Nacry, Philippe; Pridmore, Tony P; Schnepf, Andrea
The number of image analysis tools supporting the extraction of architectural features of root systems has increased in recent years. These tools offer a handy set of complementary facilities, yet it is widely accepted that none of these software tools is able to extract in an efficient way the growing array of static and dynamic features for different types of images and species. We describe the Root System Markup Language (RSML), which has been designed to overcome two major challenges: (1) to enable portability of root architecture data between different software tools in an easy and interoperable manner, allowing seamless collaborative work; and (2) to provide a standard format upon which to base central repositories that will soon arise following the expanding worldwide root phenotyping effort. RSML follows the XML standard to store two- or three-dimensional image metadata, plant and root properties and geometries, continuous functions along individual root paths, and a suite of annotations at the image, plant, or root scale at one or several time points. Plant ontologies are used to describe botanical entities that are relevant at the scale of root system architecture. An XML schema describes the features and constraints of RSML, and open-source packages have been developed in several languages (R, Excel, Java, Python, and C#) to enable researchers to integrate RSML files into popular research workflow. © 2015 American Society of Plant Biologists. All Rights Reserved.
Pound, Michael P.; Pradal, Christophe; Draye, Xavier; Godin, Christophe; Leitner, Daniel; Meunier, Félicien; Pridmore, Tony P.; Schnepf, Andrea
The number of image analysis tools supporting the extraction of architectural features of root systems has increased in recent years. These tools offer a handy set of complementary facilities, yet it is widely accepted that none of these software tools is able to extract in an efficient way the growing array of static and dynamic features for different types of images and species. We describe the Root System Markup Language (RSML), which has been designed to overcome two major challenges: (1) to enable portability of root architecture data between different software tools in an easy and interoperable manner, allowing seamless collaborative work; and (2) to provide a standard format upon which to base central repositories that will soon arise following the expanding worldwide root phenotyping effort. RSML follows the XML standard to store two- or three-dimensional image metadata, plant and root properties and geometries, continuous functions along individual root paths, and a suite of annotations at the image, plant, or root scale at one or several time points. Plant ontologies are used to describe botanical entities that are relevant at the scale of root system architecture. An XML schema describes the features and constraints of RSML, and open-source packages have been developed in several languages (R, Excel, Java, Python, and C#) to enable researchers to integrate RSML files into popular research workflow. PMID:25614065
Sycara, Katia P
CMU did research and development on semantic web services using OWL-S, the semantic web service language under the Defense Advanced Research Projects Agency- DARPA Agent Markup Language (DARPA-DAML) program...
Swat, MJ; Moodie, S; Wimalaratne, SM; Kristensen, NR; Lavielle, M; Mari, A; Magni, P; Smith, MK; Bizzotto, R; Pasotti, L; Mezzalana, E; Comets, E; Sarr, C; Terranova, N; Blaudez, E; Chan, P; Chard, J; Chatel, K; Chenel, M; Edwards, D; Franklin, C; Giorgino, T; Glont, M; Girard, P; Grenon, P; Harling, K; Hooker, AC; Kaye, R; Keizer, R; Kloft, C; Kok, JN; Kokash, N; Laibe, C; Laveille, C; Lestini, G; Mentré, F; Munafo, A; Nordgren, R; Nyberg, HB; Parra-Guillen, ZP; Plan, E; Ribba, B; Smith, G; Trocóniz, IF; Yvon, F; Milligan, PA; Harnisch, L; Karlsson, M; Hermjakob, H; Le Novère, N
The lack of a common exchange format for mathematical models in pharmacometrics has been a long-standing problem. Such a format has the potential to increase productivity and analysis quality, simplify the handling of complex workflows, ensure reproducibility of research, and facilitate the reuse of existing model resources. Pharmacometrics Markup Language (PharmML), currently under development by the Drug Disease Model Resources (DDMoRe) consortium, is intended to become an exchange standard in pharmacometrics by providing means to encode models, trial designs, and modeling steps. PMID:26225259
Park, J; Lechevalier, D; Ak, R; Ferguson, M; Law, K H; Lee, Y-T T; Rachuri, S
This paper describes Gaussian process regression (GPR) models presented in predictive model markup language (PMML). PMML is an extensible-markup-language (XML) -based standard language used to represent data-mining and predictive analytic models, as well as pre- and post-processed data. The previous PMML version, PMML 4.2, did not provide capabilities for representing probabilistic (stochastic) machine-learning algorithms that are widely used for constructing predictive models taking the associated uncertainties into consideration. The newly released PMML version 4.3, which includes the GPR model, provides new features: confidence bounds and distribution for the predictive estimations. Both features are needed to establish the foundation for uncertainty quantification analysis. Among various probabilistic machine-learning algorithms, GPR has been widely used for approximating a target function because of its capability of representing complex input and output relationships without predefining a set of basis functions, and predicting a target output with uncertainty quantification. GPR is being employed to various manufacturing data-analytics applications, which necessitates representing this model in a standardized form for easy and rapid employment. In this paper, we present a GPR model and its representation in PMML. Furthermore, we demonstrate a prototype using a real data set in the manufacturing domain.
Bajlak Ch. Oorzhak
Full Text Available The article examines the progress of semantic markup of the Electronic corpus of texts in Tuvan language (ECTTL, which is another stage of adding Tuvan texts to the database and marking up the corpus. ECTTL is a collaborative project by researchers from Tuvan State University (Research and Education Center of Turkic Studies and Department of Information Technologies. Semantic markup of Tuvan lexis will come as a search engine and reference system which will help users find text snippets containing words with desired meanings in ECTTL. The first stage of this process is setting up databases of basic lexemes of Tuvan language. All meaningful lexemes were classified into the following semantic groups: humans, animals, objects, natural objects and phenomena, and abstract concepts. All Tuvan object nouns, as well as both descriptive and relative adjectives, were assigned to one of these lexico-semantic classes. Each class, sub-class and descriptor is tagged in Tuvan, Russian and English; these tags, in turn, will help automatize searching. The databases of meaningful lexemes of Tuvan language will also outline their lexical combinations. The automatized system will contain information on semantic combinations of adjectives with nouns, adverbs with verbs, nouns with verbs, as well as on the combinations which are semantically incompatible.
Kottmann, Renzo; Gray, Tanya; Murphy, Sean; Kagan, Leonid; Kravitz, Saul; Lombardot, Thierry; Field, Dawn; Glöckner, Frank Oliver
The Genomic Contextual Data Markup Language (GCDML) is a core project of the Genomic Standards Consortium (GSC) that implements the "Minimum Information about a Genome Sequence" (MIGS) specification and its extension, the "Minimum Information about a Metagenome Sequence" (MIMS). GCDML is an XML Schema for generating MIGS/MIMS compliant reports for data entry, exchange, and storage. When mature, this sample-centric, strongly-typed schema will provide a diverse set of descriptors for describing the exact origin and processing of a biological sample, from sampling to sequencing, and subsequent analysis. Here we describe the need for such a project, outline design principles required to support the project, and make an open call for participation in defining the future content of GCDML. GCDML is freely available, and can be downloaded, along with documentation, from the GSC Web site (http://gensc.org).
.... To more effectively exchange and share data, the Defense Information Systems Agency (DISA), the lead agency for the USMTF, is actively engaged in extending the USMTF standard with a new data sharing technology called Extensible Markup Language (XML...
.... To more effectively exchange and share data, the Defense Information Systems Agency (DISA), the lead agency for the USMTF, is actively engaged in extending the USMTF standard with a new data sharing technology called Extensible Markup Language (XML...
Full Text Available In general, the Journal Article Tag Suite (JATS extensible markup language (XML coding is processed automatically by an XML filtering program. In this article, the basic tagging in JATS is explained in terms of coding practice. A text editor that supports UTF-8 encoding is necessary to input JATS XML data that works in every language. Any character representable in Unicode can be used in JATS XML, and commonly available web browsers can be used to view JATS XML files. JATS XML files can refer to document type definitions, extensible stylesheet language files, and cascading style sheets, but they must specify the locations of those files. Tools for validating JATS XML files are available via the web sites of PubMed Central and ScienceCentral. Once these files are uploaded to a web server, they can be accessed from all over the world by anyone with a browser. Encoding an example article in JATS XML may help editors in deciding on the adoption of JATS XML.
Full Text Available The lifecycle of Web-based applications is characterized by frequent changes to content, user interface, and functionality. Updating content, improving the services provided to users, drives further development of a Web-based application. The major goal for the success of a Web-based application becomes therefore its evolution. Though, development and maintenance of Web-based applications suffers from the underlying document-based implementation model. A disciplined evolution of Web based applications requires the application of software engineering practice for systematic further development and reuse of software artifacts. In this contribution we suggest to adopt the component paradigm to development and evolution of Web-based applications. The approach is based on a dedicated component technology and component-software architecture. It allows abstracting from many technical aspects related to the Web as an application platform by introducing domain specific markup languages. These languages allow the description of services, which represent domain components in our Web-component-software approach. Domain experts with limited knowledge of technical details can therefore describe application functionality and the evolution of orthogonal aspects of the application can be de-coupled. The whole approach is based on XML to achieve the necessary standardization and economic efficiency for the use in real world projects.
Management Data Initiative by Frederick S Brundick Approved for public release; distribution is unlimited. NOTICES Disclaimers The findings in this report...Schema in the Global Force Management Data Initiative by Frederick S Brundick Computing and Information Sciences Directorate, ARL Approved for public...Technical Report Producing a Data Dictionary from an Extensible Markup Language (XML) Schema in the Global Force Management Data Initiative Frederick S
de Jong, Wibe A.; Walker, Andrew M.; Hanwell, Marcus D.
Background: Multidisciplinary integrated research requires the ability to couple the diverse sets of data obtained from a range of complex experiments and computer simulations. Integrating data requires semantically rich information. In this paper an end-to-end use of semantically rich data in computational chemistry is demonstrated utilizing the Chemical Markup Language (CML) framework. Semantically rich data is generated by the NWChem computational chemistry software with the FoX library an...
Mohammed Amasha; Salem Alkhalaf
This study examines the use of Facebook Markup Language (FBML) to design an e-learning model to facilitate teaching and learning in an academic setting. The qualitative research study presents a case study on how, Facebook is used to support collaborative activities in higher education. We used FBML to design an e-learning model called processes for e-learning resources in the Specialist Learning Resources Diploma (SLRD) program. Two groups drawn from the SLRD program were used; First were th...
Zaslavsky, I.; Valentine, D.; Maidment, D.; Tarboton, D. G.; Whiteaker, T.; Hooper, R.; Kirschtel, D.; Rodriguez, M.
The CUAHSI Hydrologic Information System (HIS, his.cuahsi.org) uses web services as the core data exchange mechanism which provides programmatic connection between many heterogeneous sources of hydrologic data and a variety of online and desktop client applications. The service message schema follows the CUAHSI Water Markup Language (WaterML) 1.x specification (see OGC Discussion Paper 07-041r1). Data sources that can be queried via WaterML-compliant water data services include national and international repositories such as USGS NWIS (National Water Information System), USEPA STORET (Storage & Retrieval), USDA SNOTEL (Snowpack Telemetry), NCDC ISH and ISD(Integrated Surface Hourly and Daily Data), MODIS (Moderate Resolution Imaging Spectroradiometer), and DAYMET (Daily Surface Weather Data and Climatological Summaries). Besides government data sources, CUAHSI HIS provides access to a growing number of academic hydrologic observation networks. These networks are registered by researchers associated with 11 hydrologic observatory testbeds around the US, and other research, government and commercial groups wishing to join the emerging CUAHSI Water Data Federation. The Hydrologic Information Server (HIS Server) software stack deployed at NSF-supported hydrologic observatory sites and other universities around the country, supports a hydrologic data publication workflow which includes the following steps: (1) observational data are loaded from static files or streamed from sensors into a local instance of an Observations Data Model (ODM) database; (2) a generic web service template is configured for the new ODM instance to expose the data as a WaterML-compliant water data service, and (3) the new water data service is registered at the HISCentral registry (hiscentral.cuahsi.org), its metadata are harvested and semantically tagged using concepts from a hydrologic ontology. As a result, the new service is indexed in the CUAHSI central metadata catalog, and becomes
De Jong, Wibe A.; Walker, Andrew M.; Hanwell, Marcus D.
Background Multidisciplinary integrated research requires the ability to couple the diverse sets of data obtained from a range of complex experiments and computer simulations. Integrating data requires semantically rich information. In this paper the generation of semantically rich data from the NWChem computational chemistry software is discussed within the Chemical Markup Language (CML) framework. Results The NWChem computational chemistry software has been modified and coupled to the FoX library to write CML compliant XML data files. The FoX library was expanded to represent the lexical input files used by the computational chemistry software. Conclusions The production of CML compliant XML files for the computational chemistry software NWChem can be relatively easily accomplished using the FoX library. A unified computational chemistry or CompChem convention and dictionary needs to be developed through a community-based effort. The long-term goal is to enable a researcher to do Google-style chemistry and physics searches.
Wendt, G J
This presentation describes the technical details of implementing a process to create digital teaching files stressing the use of commercial off-the-shelf (COTS) software and hardware and standard hypertext markup language (HTML) to keep development costs to a minimum.
De Loecker, Jan; Warzynski, Frederic Michel Patrick
estimates of plant- level markups without specifying how firms compete in the product market. We rely on our method to explore the relationship be- tween markups and export behavior. We find that markups are estimated significantly higher when controlling for unobserved productivity; that exporters charge......, on average, higher markups and that markups increase upon export entry....
In this paper we introduce our idea abouthow to create a virtual reality system, wherein thefootball teams, or in our terminology, the avatars of thefootball players can play a high number of footballmatches. Based on our former experience in mobilesoccer gaming we suggest developing an appropriatemarkup language to describe the football players, thecoaches and the matches themselves. We review ourexperience in question and in present work the targetsshall be set by suggesting the development...
de Jong, Wibe A; Walker, Andrew M; Hanwell, Marcus D
Multidisciplinary integrated research requires the ability to couple the diverse sets of data obtained from a range of complex experiments and computer simulations. Integrating data requires semantically rich information. In this paper an end-to-end use of semantically rich data in computational chemistry is demonstrated utilizing the Chemical Markup Language (CML) framework. Semantically rich data is generated by the NWChem computational chemistry software with the FoX library and utilized by the Avogadro molecular editor for analysis and visualization. The NWChem computational chemistry software has been modified and coupled to the FoX library to write CML compliant XML data files. The FoX library was expanded to represent the lexical input files and molecular orbitals used by the computational chemistry software. Draft dictionary entries and a format for molecular orbitals within CML CompChem were developed. The Avogadro application was extended to read in CML data, and display molecular geometry and electronic structure in the GUI allowing for an end-to-end solution where Avogadro can create input structures, generate input files, NWChem can run the calculation and Avogadro can then read in and analyse the CML output produced. The developments outlined in this paper will be made available in future releases of NWChem, FoX, and Avogadro. The production of CML compliant XML files for computational chemistry software such as NWChem can be accomplished relatively easily using the FoX library. The CML data can be read in by a newly developed reader in Avogadro and analysed or visualized in various ways. A community-based effort is needed to further develop the CML CompChem convention and dictionary. This will enable the long-term goal of allowing a researcher to run simple "Google-style" searches of chemistry and physics and have the results of computational calculations returned in a comprehensible form alongside articles from the published literature.
Lallement, Christophe; Haiech, Jacques
The article deals with BB-SPICE (SPICE for Biochemical and Biological Systems), an extension of the famous Simulation Program with Integrated Circuit Emphasis (SPICE). BB-SPICE environment is composed of three modules: a new textual and compact description formalism for biological systems, a converter that handles this description and generates the SPICE netlist of the equivalent electronic circuit and NGSPICE which is an open-source SPICE simulator. In addition, the environment provides back and forth interfaces with SBML (System Biology Markup Language), a very common description language used in systems biology. BB-SPICE has been developed in order to bridge the gap between the simulation of biological systems on the one hand and electronics circuits on the other hand. Thus, it is suitable for applications at the interface between both domains, such as development of design tools for synthetic biology and for the virtual prototyping of biosensors and lab-on-chip. Simulation results obtained with BB-SPICE and COPASI (an open-source software used for the simulation of biochemical systems) have been compared on a benchmark of models commonly used in systems biology. Results are in accordance from a quantitative viewpoint but BB-SPICE outclasses COPASI by 1 to 3 orders of magnitude regarding the computation time. Moreover, as our software is based on NGSPICE, it could take profit of incoming updates such as the GPU implementation, of the coupling with powerful analysis and verification tools or of the integration in design automation tools (synthetic biology). PMID:28787027
Umesh, P; Naveen, F; Rao, Chanchala Uma Maheswara; Nair, Achuthsankar S
In the backdrop of accelerated efforts for creating synthetic organisms, the nature and scope of an ideal programming language for scripting synthetic organism in-silico has been receiving increasing attention. A few programming languages for synthetic biology capable of defining, constructing, networking, editing and delivering genome scale models of cellular processes have been recently attempted. All these represent important points in a spectrum of possibilities. This paper introduces Kera, a state of the art programming language for synthetic biology which is arguably ahead of similar languages or tools such as GEC, Antimony and GenoCAD. Kera is a full-fledged object oriented programming language which is tempered by biopart rule library named Samhita which captures the knowledge regarding the interaction of genome components and catalytic molecules. Prominent feature of the language are demonstrated through a toy example and the road map for the future development of Kera is also presented.
Dec 31, 2004 ... The faculty of language is unique to the human species. This implies that there are human-specific biological changes that lie at the basis of human language. However, it is not clear what the nature of such changes are, and how they could be shaped by evolution. In this paper, emphasis is laid on ...
Sánchez-de-Madariaga, Ricardo; Muñoz, Adolfo; Cáceres, Jesús; Somolinos, Roberto; Pascual, Mario; Martínez, Ignacio; Salvador, Carlos H; Monteagudo, José Luis
The objective of this paper is to introduce a new language called ccML, designed to provide convenient pragmatic information to applications using the ISO/EN13606 reference model (RM), such as electronic health record (EHR) extracts editors. EHR extracts are presently built using the syntactic and semantic information provided in the RM and constrained by archetypes. The ccML extra information enables the automation of the medico-legal context information edition, which is over 70% of the total in an extract, without modifying the RM information. ccML is defined using a W3C XML schema file. Valid ccML files complement the RM with additional pragmatics information. The ccML language grammar is defined using formal language theory as a single-type tree grammar. The new language is tested using an EHR extracts editor application as proof-of-concept system. Seven ccML PVCodes (predefined value codes) are introduced in this grammar to cope with different realistic EHR edition situations. These seven PVCodes have different interpretation strategies, from direct look up in the ccML file itself, to more complex searches in archetypes or system precomputation. The possibility to declare generic types in ccML gives rise to ambiguity during interpretation. The criterion used to overcome ambiguity is that specificity should prevail over generality. The opposite would make the individual specific element declarations useless. A new mark-up language ccML is introduced that opens up the possibility of providing applications using the ISO/EN13606 RM with the necessary pragmatics information to be practical and realistic.
PENGUKURAN KINERJA BEBERAPA SISTEM BASIS DATA RELASIONAL DENGAN KEMAMPUAN MENYIMPAN DATA BERFORMAT GML (GEOGRAPHY MARKUP LANGUAGE YANG DAPAT DIGUNAKAN UNTUK MENDASARI APLIKASI-APLIKASI SISTEM INFORMASI GEOGRAFIS
Full Text Available If we want to represent spatial data to user using GIS (Geographical Information System applications, we have 2 choices about the underlying database, that is general RDBMS (Relational Database Management System for saving general spatial data (number, char, varchar, etc., or saving spatial data in GML (Geography Markup Language format. (GML is an another XML’s special vocabulary for spatial data. If we choose GML for saving spatial data, we also have 2 choices, that is saving spatial data in XML Enabled Database (relational databases that can be use for saving XML data or we can use Native XML Database (NXD, that is special databases that can be use for saving XML data. In this paper, we try to make performance comparison for several XML Enabled Database when we do GML’s CRUD (Create-Read-Update-Delete operations to these databases. On the other side, we also want to see flexibility of XML Enabled Database from programmers view.
Van Nguyen, A; Avrin, D E; Tellis, W M; Andriole, K P; Arenson, R L
Common object request broker architecture (CORBA) is a method for invoking distributed objects across a network. There has been some activity in applying this software technology to Digital Imaging and Communications in Medicine (DICOM), but no documented demonstration of how this would actually work. We report a CORBA demonstration that is functionally equivalent and in some ways superior to the DICOM communication protocol. In addition, in and outside of medicine, there is great interest in the use of extensible markup language (XML) to provide interoperation between databases. An example implementation of the DICOM data structure in XML will also be demonstrated. Using Visibroker ORB from Inprise (Scotts Valley, CA), a test bed was developed to simulate the principle DICOM operations: store, query, and retrieve (SQR). SQR is the most common interaction between a modality device application entity (AE) such as a computed tomography (CT) scanner, and a storage component, as well as between a storage component and a workstation. The storage of a CT study by invoking one of several storage objects residing on a network was simulated and demonstrated. In addition, XML database descriptors were used to facilitate the transfer of DICOM header information between independent databases. CORBA is demonstrated to have great potential for the next version of DICOM. It can provide redundant protection against single points of failure. XML appears to be an excellent method of providing interaction between separate databases managing the DICOM information object model, and may therefore eliminate the common use of proprietary client-server databases in commercial implementations of picture archiving and communication systems (PACS).
Full Text Available The article deals with BB-SPICE (SPICE for Biochemical and Biological Systems, an extension of the famous Simulation Program with Integrated Circuit Emphasis (SPICE. BB-SPICE environment is composed of three modules: a new textual and compact description formalism for biological systems, a converter that handles this description and generates the SPICE netlist of the equivalent electronic circuit and NGSPICE which is an open-source SPICE simulator. In addition, the environment provides back and forth interfaces with SBML (System Biology Markup Language, a very common description language used in systems biology. BB-SPICE has been developed in order to bridge the gap between the simulation of biological systems on the one hand and electronics circuits on the other hand. Thus, it is suitable for applications at the interface between both domains, such as development of design tools for synthetic biology and for the virtual prototyping of biosensors and lab-on-chip. Simulation results obtained with BB-SPICE and COPASI (an open-source software used for the simulation of biochemical systems have been compared on a benchmark of models commonly used in systems biology. Results are in accordance from a quantitative viewpoint but BB-SPICE outclasses COPASI by 1 to 3 orders of magnitude regarding the computation time. Moreover, as our software is based on NGSPICE, it could take profit of incoming updates such as the GPU implementation, of the coupling with powerful analysis and verification tools or of the integration in design automation tools (synthetic biology.
Morchio, di Renzo
Some time ago I proposed in an Editorial in this journal some considerations on the language of biology. I concluded that, to realize an autonomy of such a language (and therefore of biology), we have to develop a valid language for biology. In such a context, it seemed to me that the term "metaphors" referred to the concepts concerning the information carried by genetic code, was a reasonable one. However, Barbieri's article in this issue of Rivista di Biologia / Biology Forum calls for a reply. Of course, we do not know very much in this field, even if we have some evidence that a sequence of bases on a DNA is not determined only by chance. In any case we can exclude that nature in this occasion has "invented" a code. Nature doesn't "invent" anything: it only follows its rules, that we name "laws of nature". Barbieri quotes the Morse code, but forgets to say that such a code is "conventional" in the sense that it is valid only because it is the result of an "agreement" between Morse and the users of that code. There is nothing more unnatural than a "code": with whom nature should actually have to "reach an agreement"? As a matter of fact, we interpret as "information" what happens by law of nature. Also Barbieri's thesis that genes and proteins are molecular artifacts, assembled by external agents, whereas generally molecules are determined by their bonds, i.e. by internal factors, is a disputable one. It is examined how much an external structure plays a role in ordinary chemical reactions. The "information" of physics is not a semantic information. For such information we can refer to history of literature, telegraphic offices, genetics or biochemistry.
National Aeronautics and Space Administration — The KML documentation standard provides a solution for imagery integration into mapping tools that utilize support the KML standard, specifically Google Earth. Using...
Frank, M S; Schultz, T; Dreyer, K
To provide a standardized and scaleable mechanism for exchanging digital radiologic educational content between software systems that use disparate authoring, storage, and presentation technologies. Our institution uses two distinct software systems for creating educational content for radiology. Each system is used to create in-house educational content as well as commercial educational products. One system is an authoring and viewing application that facilitates the input and storage of hierarchical knowledge and associated imagery, and is capable of supporting a variety of entity relationships. This system is primarily used for the production and subsequent viewing of educational CD-ROMS. Another software system is primarily used for radiologic education on the world wide web. This system facilitates input and storage of interactive knowledge and associated imagery, delivering this content over the internet in a Socratic manner simulating in-person interaction with an expert. A subset of knowledge entities common to both systems was derived. An additional subset of knowledge entities that could be bidirectionally mapped via algorithmic transforms was also derived. An extensible markup language (XML) object model and associated lexicon were then created to represent these knowledge entities and their interactive behaviors. Forward-looking attention was exercised in the creation of the object model in order to facilitate straightforward future integration of other sources of educational content. XML generators and interpreters were written for both systems. Deriving the XML object model and lexicon was the most critical and time-consuming aspect of the project. The coding of the XML generators and interpreters required only a few hours for each environment. Subsequently, the transfer of hundreds of educational cases and thematic presentations between the systems can now be accomplished in a matter of minutes. The use of algorithmic transforms results in nearly 100
view) explicitly formulated the study of language as a mental object. A mental object is ... tactic level? Chomsky (e.g. Chomsky 1981a,b) proposed that the language universals can be divided into two kinds. The. Principles are those that are fixed for all languages, and ..... action with the environment, mainly as changes in the.
Wang, Fusheng; Pan, Tony; Sharma, Ashish; Saltz, Joel
Proprietary approaches for representing annotations and image markup are serious barriers for researchers to share image data and knowledge. The Annotation and Image Markup (AIM) project is developing a standard based information model for image annotation and markup in health care and clinical trial environments. The complex hierarchical structures of AIM data model pose new challenges for managing such data in terms of performance and support of complex queries. In this paper, we present our work on managing AIM data through a native XML approach, and supporting complex image and annotation queries through native extension of XQuery language. Through integration with xService, AIM databases can now be conveniently shared through caGrid.
Wang, Fusheng; Pan, Tony; Sharma, Ashish; Saltz, Joel
Proprietary approaches for representing annotations and image markup are serious barriers for researchers to share image data and knowledge. The Annotation and Image Markup (AIM) project is developing a standard based information model for image annotation and markup in health care and clinical trial environments. The complex hierarchical structures of AIM data model pose new challenges for managing such data in terms of performance and support of complex queries. In this paper, we present our work on managing AIM data through a native XML approach, and supporting complex image and annotation queries through native extension of XQuery language. Through integration with xService, AIM databases can now be conveniently shared through caGrid.
De Loecker, Jan; Warzynski, Frederic
We derive an estimating equation to estimate markups using the insight of Hall (1986) and the control function approach of Olley and Pakes (1996). We rely on our method to explore the relationship between markups and export behavior using plant-level data. We find significantly higher markups when...... we control for unobserved productivity shocks. Furthermore, we find significant higher markups for exporting firms and present new evidence on markup-export status dynamics. More specifically, we find that firms' markups significantly increase (decrease) after entering (exiting) export markets. We...... see these results as a first step in opening up the productivity-export black box, and provide a potential explanation for the big measured productivity premia for firms entering export markets....
The study quantifies the relationship between retail wine price and restaurant mark-up. Ordinary Least Squares regressions were run to estimate how restaurant mark-up responded to retail price. Separate regressions were run for white wine, red wine, and both red and white combined. Both slope and intercept coefficients for each of these regressions were highly significant and indicated the expected inverse relationship between retail price and mark-up.
De Loecker, Jan; Warzynski, Frederic
and export behavior using plant-level data. We find that i) markups are estimated significantly higher when controlling for unobserved productivity, ii) exporters charge on average higher markups and iii) firms' markups increase (decrease) upon export entry (exit).We see these findings as a first step...... in opening up the productivity-export black box, and provide a potential explanation for the big measured productivity premia for firms entering export markets....
log2markup extract parts of the text version from the Stata log command and transform the logfile into a markup based document with the same name, but with extension markup (or otherwise specified in option extension) instead of log. The author usually uses markdown for writing documents. However...
Bellone, Flora; Musso, Patrick; Nesta, Lionel
In this paper, we test key micro-level theoretical predictions ofMelitz and Ottaviano (MO) (2008), a model of international trade with heterogenous firms and endogenous mark-ups. At the firm-level, the MO model predicts that: 1) firm markups are negatively related to domestic market size; 2...
Graça, Andreia Sofia Dinis
O Business Intelligence representa um conjunto de técnicas e ferramentas, que são fundamentais na melhoria do valor quantitativo e qualitativo da informação proveniente de um grande volume de dados, auxiliando na execução e implementação de estratégias de negócios, determinando, desta forma, uma grande vantagem no mercado global e no universo do empreendedorismo. As técnicas referidas anteriormente são geralmente utilizadas por consultores, sendo neste contexto, que serão abordadas as nece...
Paolo A. Netti
Full Text Available Chemical signals propagating through aqueous environment are at the basis of the language utilized by living systems to exchange information. In the last years, molecular biology has partly disclosed the grammar and the syntax of this complex language revealing the fascinating world of molecular communication that is the foundation of biological development.
Boniolo, Giovanni; D'Agostino, Marcello; Di Fiore, Pier Paolo
We propose a formal language that allows for transposing biological information precisely and rigorously into machine-readable information. This language, which we call Zsyntax (where Z stands for the Greek word zetaomegaeta, life), is grounded on a particular type of non-classical logic, and it can be used to write algorithms and computer programs. We present it as a first step towards a comprehensive formal language for molecular biology in which any biological process can be written and analyzed as a sort of logical "deduction". Moreover, we illustrate the potential value of this language, both in the field of text mining and in that of biological prediction.
Full Text Available 圖書館網站是圖書館服務的延伸，圖書館網頁之正確性與否必然關係著資訊倫理中之可及性及正確性，因此突顯出圖書館網頁是否符合網頁設計標準規範對讀者服務之重要性，而其中網頁標記語言為網頁設計標準規範的一種，透過圖書館網頁正確性檢測可清楚揭露網頁符合標準規範的程度，以協助圖書館開發或維護符合標準規範之網頁。本研究利用W3C所提供之網頁標記語言檢測服務（Markup Validation Service）檢測158所大專院校圖書館與 4間公共圖書館網站首頁，藉此探討國內公共圖書館與大專院校圖書館網頁標記語言正確性之現況。結果發現大專院校圖書館與公共圖書館網站首頁標記語言正確性之檢測通過率為0，且錯誤數超過100個以上者有1/3強，顯示國內圖書館網頁標記語言之正確性亟待改善。本研究亦對於網頁檢測發生錯誤且W3C無修改建議之處，以範例方式提出解決之建議，供圖書館製作維護網頁之參考。 Library website is the extended service of library; the correctness of library webpage is certainly related to accessibility and correctness of information ethics and also will manifest the importance of the compliance of library webpage with webpage design standard for reader service. Markup validation service is one kind among webpage design standard, and testing the correctness of library webpage can reveal the extent of the compliance of webpage with the standard in order to assist libraries to develop or maintain webpage conforming to the standard. This study utilized markup validation service provided by W3C to test the correctness of code of library homepage of 158 colleges and 24 public libraries in order to investigate the current status of the correctness of markup on webpage on the websites of domestic college and public libraries. The results showed that 0% of homepage markup
Ruben, Robert J
The development of conceptualization of a biological basis of language during the 20th century has come about, in part, through the appreciation of the central nervous system's ability to utilize varied sensory inputs, and particularly vision, to develop language. Sign language has been a part of the linguistic experience from prehistory to the present day. Data suggest that human language may have originated as a visual language and became primarily auditory with the later development of our voice/speech tract. Sign language may be categorized into two types. The first is used by individuals who have auditory/oral language and the signs are used for special situations, such as communication in a monastery in which there is a vow of silence. The second is used by those who do not have access to auditory/oral language, namely the deaf. The history of the two forms of sign language and the development of the concept of the biological basis of language are reviewed from the fourth century BC to the present day. Sign languages of the deaf have been recognized since at least the fourth century BC. The codification of a monastic sign language occurred in the seventh to eighth centuries AD. Probable synergy between the two forms of sign language occurred in the 16th century. Among other developments, the Abbey de L'Epée introduced, in the 18th century, an oral syntax, French, into a sign language based upon indigenous signs of the deaf and newly created signs. During the 19th century, the concept of a "critical" period for the acquisition of language developed; this was an important stimulus for the exploration of the biological basis of language. The introduction of techniques, e.g. evoked potentials and functional MRI, during the 20th century allowed study of the brain functions associated with language.
Emmeche, Claus; Hoffmeyer, Jesper Normann
of a program, written in a formal language in the computer. Other versions of the semiotic or "nature-as-language" metaphor uses other formal or informal aspects of language to comprehend the specific structural relations in nature as explored by molecular and evolutionary biology. This intuitively appealing......The development of form in living organisms continues to challenge biological research. The concept of biological information encoded in the genetic program that controls development forms a major part of the semiotic metaphor in biology. Development is here seen in analogy to an execution...... complex of related ideas, which has a long history in the philosophy of nature and biology, is critically reviewed. The general nature of metaphor in science is considered, and different levels of metaphorical transfer of signification is distinguished. It is argued, that the metaphors may...
Ten Raa, T.
Monopoly prices are too high. It is a price level problem, in the sense that the relative mark-ups have Ramsey optimal proportions, at least for independent constant elasticity demands. I show that this feature of monopoly prices breaks down the moment one demand is replaced by the textbook linear
The biases of individual language learners act to determine the learnability and cultural stability of languages: learners come to the language learning task with biases which make certain linguistic systems easier to acquire than others. These biases are repeatedly applied during the process of language transmission, and consequently should effect the types of languages we see in human populations. Understanding the cultural evolutionary consequences of particular learning biases is therefore central to understanding the link between language learning in individuals and language universals, common structural properties shared by all the world’s languages. This paper reviews a range of models and experimental studies which show that weak biases in individual learners can have strong effects on the structure of socially learned systems such as language, suggesting that strong universal tendencies in language structure do not require us to postulate strong underlying biases or constraints on language learning. Furthermore, understanding the relationship between learner biases and language design has implications for theories of the evolution of those learning biases: models of gene-culture coevolution suggest that, in situations where a cultural dynamic mediates between properties of individual learners and properties of language in this way, biological evolution is unlikely to lead to the emergence of strong constraints on learning.
Process calculus is the common denominator for a class of compact, idealised, domain-specific formalisms normally associated with the study of reactive concurrent systems within Computer Science. With the rise of the interactioncentred science of Systems Biology a number of bio-inspired process......), is context insensitive, while the other, a poly-variant analysis (2CFA), is context-sensitive. These analyses compute safe approximations to the set of spatial configurations that are reachable according to a given model. This is useful in the qualitative study of cellular self-organisation and, e.......g., the effects of receptor defects or drug delivery mechanisms. The property of sequential realisability. which is closely related to the function of biochemical pathways, is addressed by a variant of traditional Data Flow Analysis (DFA). This so-called ‘Pathway Analysis’ computes safe approximations to the set...
Cickovski, Trevor M.
Iteratively developing a biological model and verifying results with lab observations has become standard practice in computational biology. This process is currently facilitated by biological Problem Solving Environments (PSEs), multi-tiered and modular software frameworks which traditionally consist of two layers: a computational layer written in a high level language using design patterns, and a user interface layer which hides its details. Although PSEs have proven effective, they still enforce some communication overhead between biologists refining their models through repeated comparison with experimental observations in vitro or in vivo, and programmers actually implementing model extensions and modifications within the computational layer. I illustrate the use of biological Domain-Specific Languages (DSLs) as a middle-level PSE tier to ameliorate this problem by providing experimentalists with the ability to iteratively test and develop their models using a higher degree of expressive power compared to a graphical interface, while saving the requirement of general purpose programming knowledge. I develop two radically different biological DSLs: XML-based BIOLOGO will model biological morphogenesis using a cell-centered stochastic cellular automaton and translate into C++ modules for an object-oriented PSE C OMPUCELL3D, and MDLab will provide a set of high-level Python libraries for running molecular dynamics simulations, using wrapped functionality from the C++ PSE PROTOMOL. I describe each language in detail, including its its roles within the larger PSE and its expressibility in terms of representable phenomena, and a discussion of observations from users of the languages. Moreover I will use these studies to draw general conclusions about biological DSL development, including dependencies upon the goals of the corresponding PSE, strategies, and tradeoffs.
The study of language knowledge guided by a purely biological perspective prioritizes the study of syntax. The essential process of syntax is recursion--the ability to generate an infinite array of expressions from a limited set of elements. Researchers working within the biological perspective argue that this ability is possible only because of an innately specified genetic makeup that is specific to human beings. Such a view of language knowledge may be fully justified in discussions on biolinguistics, and in evolutionary biology. However, it is grossly inadequate in understanding language-learning problems, particularly those experienced by children with neurodevelopmental disorders such as developmental dyslexia, Williams syndrome, specific language impairment and autism spectrum disorders. Specifically, syntax-centered definitions of language knowledge completely ignore certain crucial aspects of language learning and use, namely, that language is embedded in a social context; that the role of envrironmental triggering as a learning mechanism is grossly underestimated; that a considerable extent of visuo-spatial information accompanies speech in day-to-day communication; that the developmental process itself lies at the heart of knowledge acquisition; and that there is a tremendous variation in the orthographic systems associated with different languages. All these (socio-cultural) factors can influence the rate and quality of spoken and written language acquisition resulting in much variation in phenotypes associated with disorders known to have a genetic component. Delineation of such phenotypic variability requires inputs from varied disciplines such as neurobiology, neuropsychology, linguistics and communication disorders. In this paper, I discuss published research that questions cognitive modularity and emphasises the role of the environment for understanding linguistic capabilities of children with neuro-developmental disorders. The discussion pertains
Bartley, Bryan; Beal, Jacob; Clancy, Kevin; Misirli, Goksel; Roehner, Nicholas; Oberortner, Ernst; Pocock, Matthew; Bissell, Michael; Madsen, Curtis; Nguyen, Tramy; Zhang, Zhen; Gennari, John H; Myers, Chris; Wipat, Anil; Sauro, Herbert
Synthetic biology builds upon the techniques and successes of genetics, molecular biology, and metabolic engineering by applying engineering principles to the design of biological systems. The field still faces substantial challenges, including long development times, high rates of failure, and poor reproducibility. One method to ameliorate these problems would be to improve the exchange of information about designed systems between laboratories. The Synthetic Biology Open Language (SBOL) has been developed as a standard to support the specification and exchange of biological design information in synthetic biology, filling a need not satisfied by other pre-existing standards. This document details version 2.0 of SBOL, introducing a standardized format for the electronic exchange of information on the structural and functional aspects of biological designs. The standard has been designed to support the explicit and unambiguous description of biological designs by means of a well defined data model. The standard also includes rules and best practices on how to use this data model and populate it with relevant design details. The publication of this specification is intended to make these capabilities more widely accessible to potential developers and users in the synthetic biology community and beyond.
Domain-specific markup languages and descriptive metadata: their functions in scientific resource discoveryLinguagens de marcação específicas por domínio e metadados descritivos: funções para a descoberta de recursos científicos
Marcia Lei Zeng
Full Text Available While metadata has been a strong focus within information professionals‟ publications, projects, and initiatives during the last two decades, a significant number of domain-specific markup languages have also been developing on a parallel path at the same rate as metadata standards; yet, they do not receive comparable attention. This essay discusses the functions of these two kinds of approaches in scientific resource discovery and points out their potential complementary roles through appropriate interoperability approaches.Enquanto os metadados tiveram grande foco em publicações, projetos e iniciativas dos profissionais da informação durante as últimas duas décadas, um número significativo de linguagens de marcação específicas por domínio também se desenvolveram paralelamente a uma taxa equivalente aos padrões de metadados; mas ainda não recebem atenção comparável. Esse artigo discute as funções desses dois tipos de abordagens na descoberta de recursos científicos e aponta papéis potenciais e complementares por meio de abordagens de interoperabilidade apropriadas.
Galdzicki, Michal; Clancy, Kevin P; Oberortner, Ernst; Pocock, Matthew; Quinn, Jacqueline Y; Rodriguez, Cesar A; Roehner, Nicholas; Wilson, Mandy L; Adam, Laura; Anderson, J Christopher; Bartley, Bryan A; Beal, Jacob; Chandran, Deepak; Chen, Joanna; Densmore, Douglas; Endy, Drew; Grünberg, Raik; Hallinan, Jennifer; Hillson, Nathan J; Johnson, Jeffrey D; Kuchinsky, Allan; Lux, Matthew; Misirli, Goksel; Peccoud, Jean; Plahar, Hector A; Sirin, Evren; Stan, Guy-Bart; Villalobos, Alan; Wipat, Anil; Gennari, John H; Myers, Chris J; Sauro, Herbert M
The re-use of previously validated designs is critical to the evolution of synthetic biology from a research discipline to an engineering practice. Here we describe the Synthetic Biology Open Language (SBOL), a proposed data standard for exchanging designs within the synthetic biology community. SBOL represents synthetic biology designs in a community-driven, formalized format for exchange between software tools, research groups and commercial service providers. The SBOL Developers Group has implemented SBOL as an XML/RDF serialization and provides software libraries and specification documentation to help developers implement SBOL in their own software. We describe early successes, including a demonstration of the utility of SBOL for information exchange between several different software tools and repositories from both academic and industrial partners. As a community-driven standard, SBOL will be updated as synthetic biology evolves to provide specific capabilities for different aspects of the synthetic biology workflow.
Cox, Robert Sidney
Synthetic biology builds upon the techniques and successes of genetics, molecular biology, and metabolic engineering by applying engineering principles to the design of biological systems. The field still faces substantial challenges, including long development times, high rates of failure, and poor reproducibility. One method to ameliorate these problems would be to improve the exchange of information about designed systems between laboratories. The synthetic biology open language (SBOL) has been developed as a standard to support the specification and exchange of biological design information in synthetic biology, filling a need not satisfied by other pre-existing standards. This document details version 2.2.0 of SBOL that builds upon version 2.1.0 published in last year\\'s JIB special issue. In particular, SBOL 2.2.0 includes improved description and validation rules for genetic design provenance, an extension to support combinatorial genetic designs, a new class to add non-SBOL data as attachments, a new class for genetic design implementations, and a description of a methodology to describe the entire design-build-test-learn cycle within the SBOL data model.
Ihekwaba, Adoha; Larcher, Roberto; Mardare, Radu Iulian
A. Ihekwaba, R. Larcher, R. Mardare, C. Priami. BetaWB - A language for modular representation of biological systems. In Proc. of International Conference on Systems Biology (ICSB), 2007......A. Ihekwaba, R. Larcher, R. Mardare, C. Priami. BetaWB - A language for modular representation of biological systems. In Proc. of International Conference on Systems Biology (ICSB), 2007...
Ronivaldo Braz da Silva
Full Text Available The understanding of how language is acquired and the role the brain plays in the language acquisition process are crucial because the development of language is one of the most important factcrs in human development. The analysis of language development is intrinsically connected with one's awareness of how human beings or human brains perceive, learn, control, and coordinate elaborate behaviour. The study of language development, therefore, involves research on motor, perceptual, and cognitive development. This paper reviews the three major theories of language acquisition, namely, behaviouristic, psycholinguistic, and interactionistic and examines the biological component of language acquisition and the brain's role in the language development process.
Ananthanarayanan, Vaishnavi; Thies, William
Published descriptions of biology protocols are often ambiguous and incomplete, making them difficult to replicate in other laboratories. However, there is increasing benefit to formalizing the descriptions of protocols, as laboratory automation systems (such as microfluidic chips) are becoming increasingly capable of executing them. Our goal in this paper is to improve both the reproducibility and automation of biology experiments by using a programming language to express the precise series of steps taken. We have developed BioCoder, a C++ library that enables biologists to express the exact steps needed to execute a protocol. In addition to being suitable for automation, BioCoder converts the code into a readable, English-language description for use by biologists. We have implemented over 65 protocols in BioCoder; the most complex of these was successfully executed by a biologist in the laboratory using BioCoder as the only reference. We argue that BioCoder exposes and resolves ambiguities in existing protocols, and could provide the software foundations for future automation platforms. BioCoder is freely available for download at http://research.microsoft.com/en-us/um/india/projects/biocoder/. BioCoder represents the first practical programming system for standardizing and automating biology protocols. Our vision is to change the way that experimental methods are communicated: rather than publishing a written account of the protocols used, researchers will simply publish the code. Our experience suggests that this practice is tractable and offers many benefits. We invite other researchers to leverage BioCoder to improve the precision and completeness of their protocols, and also to adapt and extend BioCoder to new domains.
Full Text Available nerating huge amounts of data, which typically must be shared amongst many collaborators and researchers. To... store and use such data efficiently, it is paramount that biomedical researchers
Full Text Available description form. It was an outcome of the conference that we proposed the initial submission of PML to Life...ference was fruitful, we decided such international conference to be executed conti...st for proposal for the standardization of genomic variation data description form in January 2004. Because the 1st international con
Full Text Available The semantic models of sentences with verbs of motion in German standard language and in scientific language used in biology are analyzed in the article. In its theoretic part it is affirmed that the article is based on the semantic theory of the sentence. This theory, in its turn, is grounded on the correlation of semantic predicative classes and semantic roles. The combination of semantic predicative classes and semantic roles is expressed by the main semantic formula – proposition. In its practical part the differences between the semantic models of standard and scientific language used in biology are explained. While modelling sentences with verbs of motion, two groups of semantic models of sentences are singled out: that of action (Handlung and process (Vorgang. The analysis shows that the semantic models of sentences with semantic action predicatives dominate in the text of standard language while the semantic models of sentences with semantic process predicatives dominate in the texts of scientific language used in biology. The differences how the doer and direction are expressed in standard and in scientific language are clearly seen and the semantic cases (Agens, Patiens, Direktiv1 help to determine that. It is observed that in scientific texts of high level of specialization (biology science in contrast to popular scientific literature models of sentences with moving verbs are usually seldom found. They are substituted by denominative constructions. In conclusions it is shown that this analysis can be important in methodics, especially planning material for teaching professional-scientific language.
Penev, Lyubomir; Lyal, Christopher Hc; Weitzman, Anna; Morse, David R; King, David; Sautter, Guido; Georgiev, Teodor; Morris, Robert A; Catapano, Terry; Agosti, Donat
We review the three most widely used XML schemas used to mark-up taxonomic texts, TaxonX, TaxPub and taXMLit. These are described from the viewpoint of their development history, current status, implementation, and use cases. The concept of "taxon treatment" from the viewpoint of taxonomy mark-up into XML is discussed. TaxonX and taXMLit are primarily designed for legacy literature, the former being more lightweight and with a focus on recovery of taxon treatments, the latter providing a much more detailed set of tags to facilitate data extraction and analysis. TaxPub is an extension of the National Library of Medicine Document Type Definition (NLM DTD) for taxonomy focussed on layout and recovery and, as such, is best suited for mark-up of new publications and their archiving in PubMedCentral. All three schemas have their advantages and shortcomings and can be used for different purposes.
Hirschman, Lynette; Fort, Karën; Boué, Stéphanie; Kyrpides, Nikos; Islamaj Doğan, Rezarta; Cohen, Kevin Bretonnel
Crowdsourcing is increasingly utilized for performing tasks in both natural language processing and biocuration. Although there have been many applications of crowdsourcing in these fields, there have been fewer high-level discussions of the methodology and its applicability to biocuration. This paper explores crowdsourcing for biocuration through several case studies that highlight different ways of leveraging 'the crowd'; these raise issues about the kind(s) of expertise needed, the motivations of participants, and questions related to feasibility, cost and quality. The paper is an outgrowth of a panel session held at BioCreative V (Seville, September 9-11, 2015). The session consisted of four short talks, followed by a discussion. In their talks, the panelists explored the role of expertise and the potential to improve crowd performance by training; the challenge of decomposing tasks to make them amenable to crowdsourcing; and the capture of biological data and metadata through community editing.Database URL: http://www.mitre.org/publications/technical-papers/crowdsourcing-and-curation-perspectives. © The Author(s) 2016. Published by Oxford University Press.
M. Montone (Maurizio)
textabstractI find that risk-averse bookmakers should charge a higher mark-up on events with a greater number of outcomes. Also, they should dynamically adjust their odds to reduce profit volatility, thus generating arbitrage opportunities. An empirical analysis of the online betting market supports
Longa, Victor Manuel
While language was traditionally considered a purely cultural trait, the advent of Noam Chomsky's Generative Grammar in the second half of the twentieth century dramatically challenged that view. According to that theory, language is an innate feature, part of the human biological endowment. If language is indeed innate, it had to biologically evolve. This review has two main objectives: firstly, it characterizes from a Chomskyan perspective the evolutionary processes by which language could have come into being. Secondly, it proposes a new method for interpreting the archaeological record that radically differs from the usual types of evidence Paleoanthropology has concentrated on when dealing with language evolution: while archaeological remains have usually been regarded from the view of the behavior they could be associated with, the paper will consider archaeological remains from the view of the computational processes and capabilities at work for their production. This computational approach, illustrated with a computational analysis of prehistoric geometric engravings, will be used to challenge the usual generative thinking on language evolution, based on the high specificity of language. The paper argues that the biological machinery of language is neither specifically linguistic nor specifically human, although language itself can still be considered a species-specific innate trait. From such a view, language would be one of the consequences of a slight modification operated on an ancestral architecture shared with vertebrates.
van der Lely, Heather K J; Pinker, Steven
Specific language impairment (SLI), a genetic developmental disorder, offers insights into the neurobiological and computational organization of language. A subtype, Grammatical-SLI (G-SLI), involves greater impairments in 'extended' grammatical representations, which are nonlocal, hierarchical, abstract, and composed, than in 'basic' ones, which are local, linear, semantic, and holistic. This distinction is seen in syntax, morphology, and phonology, and may be tied to abnormalities in the left hemisphere and basal ganglia, consistent with new models of the neurobiology of language which distinguish dorsal and ventral processing streams. Delineating neurolinguistic phenotypes promises a better understanding of the effects of genes on the brain circuitry underlying normal and impaired language abilities. Copyright © 2014 Elsevier Ltd. All rights reserved.
Raikov, Ivan; De Schutter, Erik
We present a new approach to modeling languages for computational biology, which we call the layer-oriented approach. The approach stems from the observation that many diverse biological phenomena are described using a small set of mathematical formalisms (e.g. differential equations), while at the same time different domains and subdomains of computational biology require that models are structured according to the accepted terminology and classification of that domain. Our approach uses distinct semantic layers to represent the domain-specific biological concepts and the underlying mathematical formalisms. Additional functionality can be transparently added to the language by adding more layers. This approach is specifically concerned with declarative languages, and throughout the paper we note some of the limitations inherent to declarative approaches. The layer-oriented approach is a way to specify explicitly how high-level biological modeling concepts are mapped to a computational representation, while abstracting away details of particular programming languages and simulation environments. To illustrate this process, we define an example language for describing models of ionic currents, and use a general mathematical notation for semantic transformations to show how to generate model simulation code for various simulation environments. We use the example language to describe a Purkinje neuron model and demonstrate how the layer-oriented approach can be used for solving several practical issues of computational neuroscience model development. We discuss the advantages and limitations of the approach in comparison with other modeling language efforts in the domain of computational biology and outline some principles for extensible, flexible modeling language design. We conclude by describing in detail the semantic transformations defined for our language. PMID:22615554
Full Text Available In this article, we propose a domain specific language, GUBS (Genomic Unified Behavior Specification, dedicated to the behavioral specification of synthetic biological devices, viewed as discrete open dynamical systems. GUBS is a rule-based declarative language. By contrast to a closed system, a program is always a partial description of the behavior of the system. The semantics of the language accounts the existence of some hidden non-specified actions possibly altering the behavior of the programmed device. The compilation framework follows a scheme similar to automatic theorem proving, aiming at improving synthetic biological design safety.
Zuidema, W.; de Boer, B.
Theories of the evolutionary origins of language must be informed by empirical and theoretical results from a variety of different fields. Complementing recent surveys of relevant work from linguistics, animal behaviour and genetics, this paper surveys the requirements on evolutionary scenarios that
Full Text Available The Systems Biological Graphical Notation (SBGN is an international community effort for standardized graphical representations of biological pathways and networks. The goal of SBGN is to provide unambiguous pathway and network maps for readers with different scientific backgrounds as well as to support efficient and accurate exchange of biological knowledge between different research communities, industry, and other players in systems biology. Three SBGN languages, Process Description (PD, Entity Relationship (ER and Activity Flow (AF, allow for the representation of different aspects of biological and biochemical systems at different levels of detail.
Full Text Available The Systems Biological Graphical Notation (SBGN is an international community effort for standardized graphical representations of biological pathways and networks. The goal of SBGN is to provide unambiguous pathway and network maps for readers with different scientific backgrounds as well as to support efficient and accurate exchange of biological knowledge between different research communities, industry, and other players in systems biology. Three SBGN languages, Process Description (PD, Entity Relationship (ER and Activity Flow (AF, allow for the representation of different aspects of biological and biochemical systems at different levels of detail.
Moodie, Stuart; Le Novère, Nicolas; Demir, Emek; Mi, Huaiyu; Villéger, Alice
The Systems Biological Graphical Notation (SBGN) is an international community effort for standardized graphical representations of biological pathways and networks. The goal of SBGN is to provide unambiguous pathway and network maps for readers with different scientific backgrounds as well as to support efficient and accurate exchange of biological knowledge between different research communities, industry, and other players in systems biology. Three SBGN languages, Process Description (PD), Entity Relationship (ER) and Activity Flow (AF), allow for the representation of different aspects of biological and biochemical systems at different levels of detail. The SBGN Process Description language represents biological entities and processes between these entities within a network. SBGN PD focuses on the mechanistic description and temporal dependencies of biological interactions and transformations. The nodes (elements) are split into entity nodes describing, e.g., metabolites, proteins, genes and complexes, and process nodes describing, e.g., reactions and associations. The edges (connections) provide descriptions of relationships (or influences) between the nodes, such as consumption, production, stimulation and inhibition. Among all three languages of SBGN, PD is the closest to metabolic and regulatory pathways in biological literature and textbooks, but its well-defined semantics offer a superior precision in expressing biological knowledge.
Sorokin, Anatoly; Le Novère, Nicolas; Luna, Augustin; Czauderna, Tobias; Demir, Emek; Haw, Robin; Mi, Huaiyu; Moodie, Stuart; Schreiber, Falk; Villéger, Alice
The Systems Biological Graphical Notation (SBGN) is an international community effort for standardized graphical representations of biological pathways and networks. The goal of SBGN is to provide unambiguous pathway and network maps for readers with different scientific backgrounds as well as to support efficient and accurate exchange of biological knowledge between different research communities, industry, and other players in systems biology. Three SBGN languages, Process Description (PD), Entity Relationship (ER) and Activity Flow (AF), allow for the representation of different aspects of biological and biochemical systems at different levels of detail. The SBGN Entity Relationship language (ER) represents biological entities and their interactions and relationships within a network. SBGN ER focuses on all potential relationships between entities without considering temporal aspects. The nodes (elements) describe biological entities, such as proteins and complexes. The edges (connections) provide descriptions of interactions and relationships (or influences), e.g., complex formation, stimulation and inhibition. Among all three languages of SBGN, ER is the closest to protein interaction networks in biological literature and textbooks, but its well-defined semantics offer a superior precision in expressing biological knowledge.
Mi, Huaiyu; Schreiber, Falk; Moodie, Stuart; Czauderna, Tobias; Demir, Emek; Haw, Robin; Luna, Augustin; Le Novère, Nicolas; Sorokin, Anatoly; Villéger, Alice
The Systems Biological Graphical Notation (SBGN) is an international community effort for standardized graphical representations of biological pathways and networks. The goal of SBGN is to provide unambiguous pathway and network maps for readers with different scientific backgrounds as well as to support efficient and accurate exchange of biological knowledge between different research communities, industry, and other players in systems biology. Three SBGN languages, Process Description (PD), Entity Relationship (ER) and Activity Flow (AF), allow for the representation of different aspects of biological and biochemical systems at different levels of detail. The SBGN Activity Flow language represents the influences of activities among various entities within a network. Unlike SBGN PD and ER that focus on the entities and their relationships with others, SBGN AF puts the emphasis on the functions (or activities) performed by the entities, and their effects to the functions of the same or other entities. The nodes (elements) describe the biological activities of the entities, such as protein kinase activity, binding activity or receptor activity, which can be easily mapped to Gene Ontology molecular function terms. The edges (connections) provide descriptions of relationships (or influences) between the activities, e.g., positive influence and negative influence. Among all three languages of SBGN, AF is the closest to signaling pathways in biological literature and textbooks, but its well-defined semantics offer a superior precision in expressing biological knowledge.
Wallon, Robert C; Jasti, Chandana; Hug, Barbara
The activity described in this article is designed to provide biology students with opportunities to engage in a range of academic language as they learn the discipline-specific meanings of the terms "drug," "poison," "toxicant," and "toxin." Although intended as part of an introductory lesson in a comprehensive unit for the high school level, this approach to teaching academic language can be adapted for use with older or younger students and can be modified to teach other terms.
Full Text Available The article analyzed the main results of medico-biological directions in the study of the factors of children's speech and language. It shows that a variety of pre-, peri-and neonatal developmental factors (teratogenic effects, prematurity, low birth weight, maternal diseases during pregnancy, and chronic diseases of the child had a negative impact on the child-parent relationship that has a lasting influence on child speech and language development.
Gautier, Arnaud; Rodriguez, Raphaël
Chemical biology, the science of understanding biological processes at the molecular level, has grown exponentially with the development of chemical strategies to manipulate and quantify biology with unprecedented precision. Recent advances presented at the Université Paris Sciences et Lettres symposium are discussed. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.
Myers, Chris J.
A synthetic biology workflow is composed of data repositories that provide information about genetic parts, sequence-level design tools to compose these parts into circuits, visualization tools to depict these designs, genetic design tools to select parts to create systems, and modeling and simulation tools to evaluate alternative design choices. Data standards enable the ready exchange of information within such a workflow, allowing repositories and tools to be connected from a diversity of sources. The present paper describes one such workflow that utilizes, among others, the Synthetic Biology Open Language (SBOL) to describe genetic designs, the Systems Biology Markup Language to model these designs, and SBOL Visual to visualize these designs. We describe how a standard-enabled workflow can be used to produce types of design information, including multiple repositories and software tools exchanging information using a variety of data standards. Recently, the ACS Synthetic Biology journal has recommended the use of SBOL in their publications.
Full Text Available The paper follows the idea of heterodox economists that a cost-plus price is above all a reproductive price and growth price. The authors apply a firm-level model of markup determination which, in line with theory and empirical evidence, contains proposed firm-specific determinants of the markup, including the firm’s planned growth. The positive firm-level relationship between growth and markup that is found in data for Slovenian manufacturing firms implies that retained profits gathered via the markup are an important source of growth financing and that the investment decisions of Slovenian manufacturing firms affect their pricing policy and decisions on the markup size as proposed by Post-Keynesian theory. The authors thus conclude that at least a partial trade-off between a firm’s growth and competitive outcome exists in Slovenian manufacturing.
Discussion of XML (extensible markup language) and the traditional DTD (document type definition) format focuses on efforts of the World Wide Web Consortium's XML schema working group to develop a schema language to replace DTD that will be capable of defining the set of constraints of any possible data resource. (Contains 14 references.) (LRW)
Beal, Jacob; Lu, Ting; Weiss, Ron
The field of synthetic biology promises to revolutionize our ability to engineer biological systems, providing important benefits for a variety of applications. Recent advances in DNA synthesis and automated DNA assembly technologies suggest that it is now possible to construct synthetic systems of significant complexity. However, while a variety of novel genetic devices and small engineered gene networks have been successfully demonstrated, the regulatory complexity of synthetic systems that have been reported recently has somewhat plateaued due to a variety of factors, including the complexity of biology itself and the lag in our ability to design and optimize sophisticated biological circuitry. To address the gap between DNA synthesis and circuit design capabilities, we present a platform that enables synthetic biologists to express desired behavior using a convenient high-level biologically-oriented programming language, Proto. The high level specification is compiled, using a regulatory motif based mechanism, to a gene network, optimized, and then converted to a computational simulation for numerical verification. Through several example programs we illustrate the automated process of biological system design with our platform, and show that our compiler optimizations can yield significant reductions in the number of genes (~ 50%) and latency of the optimized engineered gene networks. Our platform provides a convenient and accessible tool for the automated design of sophisticated synthetic biological systems, bridging an important gap between DNA synthesis and circuit design capabilities. Our platform is user-friendly and features biologically relevant compiler optimizations, providing an important foundation for the development of sophisticated biological systems.
Cserer, Amelie; Seiringer, Alexandra
This article is concerned with the representation of Synthetic Biology in the media and by biotechnology experts. An analysis was made of German-language media articles published between 2004 and 2008, and interviews with biotechnology-experts at the Synthetic Biology conference SB 3.0 in Zurich 2007. The results have been reflected in terms of the definition of Synthetic Biology, applications of Synthetic Biology and the perspectives of opportunities and risks. In the media, Synthetic Biology is represented as a new scientific field of biology with an engineering-like thinking, while the scientists interviewed mostly define Synthetic Biology as contrary to nature and the natural system. Media articles present Synthetic Biology broadly with positive potential and inform the publics less about the potential risks than about the benefits of Synthetic Biology. In contrast, the experts interviewed reflect more on the risks than the opportunities of Synthetic Biology. Both used metaphors to describe Synthetic Biology and its aspects.
This study explored three aspects related to ESL students in a mainstream grade 11 biology classroom: (1) the nature of students' participation in classroom activities, (2) the factors that enhanced or constrained ESL students' engagement in social interactions, and (3) the role of language in the learning of science. Ten ESL students were observed over an eight-month period in this biology classroom. Data were collected using qualitative research methods such as participant observation, audio-recordings of lessons, field notes, semi-structured interviews, short lesson recall interviews and students' written work. The study was framed within sociocultural perspectives, particularly the social constructivist perspectives of Vygotsky (1962, 1978) and Wertsch (1991). Data were analysed with respect to the three research aspects. Firstly, the findings showed that ESL students' preferred and exhibited a variety of participation practices that ranged from personal-individual to socio-interactive in nature. Both personal-individual and socio-interactive practices appeared to support science and language learning. Secondly, the findings indicated that ESL students' engagement in classroom social interactions was most likely influenced by the complex interactions between a number of competing factors at the individual, interpersonal and community/cultural levels (Rogoff, Radziszewska, & Masiello, 1995). In this study, six factors that appeared to enhance or constrain ESL students' engagement in classroom social interactions were identified. These factors were socio-cultural factors, prior classroom practice, teaching practices, affective factors, English language proficiency, and participation in the research project. Thirdly, the findings indicated that language played a significant mediational role in ESL students' learning of science. The data revealed that the learning of science terms and concepts can be explained by a functional model of language that includes: (1
Cox, Robert Sidney
People who are engineering biological organisms often find it useful to communicate in diagrams, both about the structure of the nucleic acid sequences that they are engineering and about the functional relationships between sequence features and other molecular species. Some typical practices and conventions have begun to emerge for such diagrams. The Synthetic Biology Open Language Visual (SBOL Visual) has been developed as a standard for organizing and systematizing such conventions in order to produce a coherent language for expressing the structure and function of genetic designs. This document details version 2.0 of SBOL Visual, which builds on the prior SBOL Visual 1.0 standard by expanding diagram syntax to include functional interactions and molecular species, making the relationship between diagrams and the SBOL data model explicit, supporting families of symbol variants, clarifying a number of requirements and best practices, and significantly expanding the collection of diagram glyphs.
Fesenko, S.; Isamov, N.; Barnett, C.L.; Beresford, N.A.; Howard, B.J.; Sanzharova, N.; Fesenko, E.
Extensive studies on transfer of radionuclides to animals were carried out in the USSR from the 1950s. Few of these studies were published in the international refereed literature or taken into account in international reviews. This paper continues a series of reviews of Russian language literature on radionuclide transfer to animals, providing information on biological half-lives of radionuclides in various animal tissues. The data are compared, where possible, with those reported in other countries. The data are normally quantified using a single or double exponential accounting for different proportions of the loss. For some products, such as milk, biological half-lives tend to be rapid at 1–3 d for most radionuclides and largely described by a single exponential. However, for other animal products biological half-lives can vary widely as they are influenced by many factors such as the age and size of the animal. Experimental protocols, such as the duration of the study, radionuclide administration and/or sample collection protocol also influence the value of biological half-lives estimated. - Highlights: • The data on biological half-lives from Russian language literature were reviewed. • Radionuclides with the shortest half-lives in animals are those which accumulate in soft tissues. • Short term behaviour is affected by the form in which radionuclides are administered. • There is a tendency for more rapid radionuclide turnover in younger animals
Cerullo, Marcelo; Chen, Sophia Y; Dillhoff, Mary; Schmidt, Carl R; Canner, Joseph K; Pawlik, Timothy M
Increasing hospital market concentration (with concomitantly decreasing hospital market competition) may be associated with rising hospital prices. Hospital markup - the relative increase in price over costs - has been associated with greater hospital market concentration. Patients undergoing a cardiothoracic or gastrointestinal procedure in the 2008-2011 Nationwide Inpatient Sample (NIS) were identified and linked to Hospital Market Structure Files. The association between market concentration, hospital markup and hospital for-profit status was assessed using mixed-effects log-linear models. A weighted total of 1,181,936 patients were identified. In highly concentrated markets, private for-profit status was associated with an 80.8% higher markup compared to public/private not-for-profit status (95%CI: +69.5% - +96.9%; p markets was associated with only a 62.9% higher markup compared to public/private not-for-profit status in unconcentrated markets (95%CI: +45.4% - +81.1%; p market concentration and markup. Government and private not-for-profit hospitals employed lower markups in more concentrated markets, whereas private for-profit hospitals employed higher markups in more concentrated markets. Copyright © 2017 Elsevier Inc. All rights reserved.
Analysis of English language learner performance on the biology Massachusetts comprehensive assessment system: The impact of english proficiency, first language characteristics, and late-entry ELL status
Mitchell, Mary A.
This study analyzed English language learner (ELL) performance on the June 2012 Biology MCAS, namely on item attributes of domain, cognitive skill, and linguistic complexity. It examined the impact of English proficiency, Latinate first language, first language orthography, and late-entry ELL status. The results indicated that English proficiency was a strong predictor of performance and that ELLs at higher levels of English proficiency overwhelmingly passed. The results further indicated that English proficiency introduced a construct-irrelevant variance on the Biology MCAS and raised validity issues for using this assessment at lower levels of English proficiency. This study also found that ELLs with a Latinate first language consistently had statistically significant lower performance. Late-entry ELL status did not predict Biology MCAS performance.
Bornstein, Marc H.; Hahn, Chun-Shin; Putnick, Diane L.
Background: Command of language is a fundamental skill, a cornerstone of multiple cognitive and socioemotional aspects of development, and a necessary ingredient of successful adjustment and functioning in society. Little is known about the developmental stability of language in at-risk youth or which biological and social risk factors moderate…
Full Text Available The field of synthetic biology promises to revolutionize our ability to engineer biological systems, providing important benefits for a variety of applications. Recent advances in DNA synthesis and automated DNA assembly technologies suggest that it is now possible to construct synthetic systems of significant complexity. However, while a variety of novel genetic devices and small engineered gene networks have been successfully demonstrated, the regulatory complexity of synthetic systems that have been reported recently has somewhat plateaued due to a variety of factors, including the complexity of biology itself and the lag in our ability to design and optimize sophisticated biological circuitry.To address the gap between DNA synthesis and circuit design capabilities, we present a platform that enables synthetic biologists to express desired behavior using a convenient high-level biologically-oriented programming language, Proto. The high level specification is compiled, using a regulatory motif based mechanism, to a gene network, optimized, and then converted to a computational simulation for numerical verification. Through several example programs we illustrate the automated process of biological system design with our platform, and show that our compiler optimizations can yield significant reductions in the number of genes (~ 50% and latency of the optimized engineered gene networks.Our platform provides a convenient and accessible tool for the automated design of sophisticated synthetic biological systems, bridging an important gap between DNA synthesis and circuit design capabilities. Our platform is user-friendly and features biologically relevant compiler optimizations, providing an important foundation for the development of sophisticated biological systems.
Ganapathiraju Madhavi K
Full Text Available Abstract Background It has been suggested previously that genome and proteome sequences show characteristics typical of natural-language texts such as "signature-style" word usage indicative of authors or topics, and that the algorithms originally developed for natural language processing may therefore be applied to genome sequences to draw biologically relevant conclusions. Following this approach of 'biological language modeling', statistical n-gram analysis has been applied for comparative analysis of whole proteome sequences of 44 organisms. It has been shown that a few particular amino acid n-grams are found in abundance in one organism but occurring very rarely in other organisms, thereby serving as genome signatures. At that time proteomes of only 44 organisms were available, thereby limiting the generalization of this hypothesis. Today nearly 1,000 genome sequences and corresponding translated sequences are available, making it feasible to test the existence of biological language models over the evolutionary tree. Results We studied whole proteome sequences of 970 microbial organisms using n-gram frequencies and cross-perplexity employing the Biological Language Modeling Toolkit and Patternix Revelio toolkit. Genus-specific signatures were observed even in a simple unigram distribution. By taking statistical n-gram model of one organism as reference and computing cross-perplexity of all other microbial proteomes with it, cross-perplexity was found to be predictive of branch distance of the phylogenetic tree. For example, a 4-gram model from proteome of Shigellae flexneri 2a, which belongs to the Gammaproteobacteria class showed a self-perplexity of 15.34 while the cross-perplexity of other organisms was in the range of 15.59 to 29.5 and was proportional to their branching distance in the evolutionary tree from S. flexneri. The organisms of this genus, which happen to be pathotypes of E.coli, also have the closest perplexity values with
Costa, Luís; Palma, Nuno
In this note we show that the claim from Chen et al (2005) that their model generates an endogenous markup is incorrect. This is not only a nomenclature issue: using the �fixed markup which we show to be the only one consistent with the structure of the model implies the main conclusions in that paper do not hold. In particular, government expenditure in infrastructure cannot affect the business cycle in this model by deliberately changing the market structure of the economy.
Sadowski, Michael I; Grant, Chris; Fell, Tim S
Building robust manufacturing processes from biological components is a task that is highly complex and requires sophisticated tools to describe processes, inputs, and measurements and administrate management of knowledge, data, and materials. We argue that for bioengineering to fully access biological potential, it will require application of statistically designed experiments to derive detailed empirical models of underlying systems. This requires execution of large-scale structured experimentation for which laboratory automation is necessary. This requires development of expressive, high-level languages that allow reusability of protocols, characterization of their reliability, and a change in focus from implementation details to functional properties. We review recent developments in these areas and identify what we believe is an exciting trend that promises to revolutionize biotechnology. Copyright © 2015 The Authors. Published by Elsevier Ltd.. All rights reserved.
Fesenko, S; Isamov, N; Barnett, C L; Beresford, N A; Howard, B J; Sanzharova, N; Fesenko, E
Extensive studies on transfer of radionuclides to animals were carried out in the USSR from the 1950s. Few of these studies were published in the international refereed literature or taken into account in international reviews. This paper continues a series of reviews of Russian language literature on radionuclide transfer to animals, providing information on biological half-lives of radionuclides in various animal tissues. The data are compared, where possible, with those reported in other countries. The data are normally quantified using a single or double exponential accounting for different proportions of the loss. For some products, such as milk, biological half-lives tend to be rapid at 1-3 d for most radionuclides and largely described by a single exponential. However, for other animal products biological half-lives can vary widely as they are influenced by many factors such as the age and size of the animal. Experimental protocols, such as the duration of the study, radionuclide administration and/or sample collection protocol also influence the value of biological half-lives estimated. Copyright © 2015 Elsevier Ltd. All rights reserved.
Maks, E.; Tiberius, C.; van Veenendaal, R.; Calzolari, N.; Choukri, K.; Maegaard, B.; Mariani, J.; Odjik, J.; Piperidis, S.; Tapias, D.
The Dutch HLT agency for language and speech technology (known as TST-centrale) at the Institute for Dutch Lexicology is responsible for the maintenance, distribution and accessibility of (Dutch) digital language resources. In this paper we present a project which aims to standardise the format of a
Sanden, Guro Refsum
Purpose: – The purpose of this paper is to analyse the consequences of globalisation in the area of corporate communication, and investigate how language may be managed as a strategic resource. Design/methodology/approach: – A review of previous studies on the effects of globalisation on corporate...... communication and the implications of language management initiatives in international business. Findings: – Efficient language management can turn language into a strategic resource. Language needs analyses, i.e. linguistic auditing/language check-ups, can be used to determine the language situation...
Gschmeidler, Brigitte; Seiringer, Alexandra
Although still a side issue in the German-language media, attention towards synthetic biology has risen clearly during the last years, in line with the first applications being presented. This paper presents findings from a content analysis of synthetic biology coverage in German-language media over the years 2004-2009. In the media, synthetic biology is not clearly separated from gene technology. News value is attributed to established categories such as persons and events. Many metaphors and analogies used in describing gene technology can also be found in the coverage of synthetic biology; however, engineering metaphors are more prominent. In addition, playfulness constitutes an aspect rarely found in genetic engineering coverage. Overall, the picture emerging is ambivalent, which leaves prospects for the further development of public debate ambiguous.
Cruz, Maria B.
English language learners studying biology face a dual challenge of mastering both content and language. Teaching ELLs how to engage in scientific discourse using appropriate language to ask, answer, explain, and make predictions about science requires a foundational knowledge of content-specific vocabulary. This study used qualitative interviews with intermediate-level ELLs at an American high school to learn how a supplemental iPod-based vocabulary review tool influenced their perceptions of learning biology vocabulary outside of classroom hours. Interviews with their biology teacher were also used to complement student testimony from the point of view of an educational professional with ELL teaching experience. Past studies in the area of mobile learning have primarily employed questionnaires to gather feedback from participants. This research study adds greater participant voice to the body of literature that encompasses mobile language learning, second language acquisition, and science education by presenting nuanced opinions from both students and teachers. This dissertation concludes with a discussion on the influence that this study could have on further research in the fields of mobile learning, academic vocabulary, and student learning behaviors.
Van Horne, Sam; Russell, Jae-eun; Schuh, Kathy L.
Researchers have more often examined whether students prefer using an e-textbook over a paper textbook or whether e-textbooks provide a better resource for learning than paper textbooks, but students' adoption of mark-up tools has remained relatively unexamined. Drawing on the concept of Innovation Diffusion Theory, we used educational data mining…
There is a predominant preposition in trade theory that firms operating in an imperfect market with trade barriers often set prices with a positive mark-up. Workers using insider information tend to bargain and share the rent from firms' market power; which is negatively associated with to decline with trade reforms. Empirical ...
Lamorgese, A.R.; Linarello, A.; Warzynski, Frederic Michel Patrick
In this paper, we use detailed information about firms' product portfolio to study how trade liberalization affects prices, markups and productivity. We document these effects using firm product level data in Chilean manufacturing following two major trade agreements with the EU and the US...
In web projects it is often necessary to mix XML notation and program notation in a single document or program. In mono-lingual situations, the XML notation is either subsumed in the program or the program notation is subsumed in the XML document. As an introduction we analyze XML notation...... and programming notation in relation to each other. As the main contribution of the paper we describe a number of general issues to consider when subsuming XML in a given programming language....
Full Text Available Traditionally,studies of scientific productivity are biased in two ways: they are based on Current Contents, an index centered in British and American journals, and they seldom correct for population size, ignoring the relative effort that each society places in research. We studied national productivity for biology using a more representative index, the Biological Abstracts, and analyzed both total and relative productivity. English dominates biological publications with 87% (no other individual language reaches 2%. If the USA is considered a region by itself, it occupies the first place in per capita production of biology papers, with at least twice the productivity of either Asia or Europe. Canada, Oceania and Latin America occupy an intermediate position. The global output of scientific papers is dominated by Europe, USA, Japan, Canada, China and India. When corrected for population size, the countries with the greatest productivity of biology papers are the Nordic nations, Israel, Switzerland, Netherlands, Australia, Saint Lucia and Montserrat. The predominance of English as the language of biological research found in this study shows a continuation of the trend initiated around the year 1900. The large relative productivity of the USA reflects the importance that American society gives to science as the basis for technological and economic development, but the USA’s share of total scientific output has decreased from 44% in 1983 to 34% in 2002, while there is a greater growth of science in India, Japan and Latin America, among others. The increasing share obtained by China and India may reflect a recent change in attitude towards funding science. The leadership of Nordic nations, Israel, Switzerland, Netherlands and Australia can be explained by cultural attitude. Apparently, a positive trend is emerging in Latin America, where Chile improved its ranking in per capita productivity but Argentina, Costa Rica, Uruguay, Brazil and Cuba fell
Dean, Dennis A.; Adler, Gail K.; Nguyen, David P.; Klerman, Elizabeth B.
We present a novel approach for analyzing biological time-series data using a context-free language (CFL) representation that allows the extraction and quantification of important features from the time-series. This representation results in Hierarchically AdaPtive (HAP) analysis, a suite of multiple complementary techniques that enable rapid analysis of data and does not require the user to set parameters. HAP analysis generates hierarchically organized parameter distributions that allow multi-scale components of the time-series to be quantified and includes a data analysis pipeline that applies recursive analyses to generate hierarchically organized results that extend traditional outcome measures such as pharmacokinetics and inter-pulse interval. Pulsicons, a novel text-based time-series representation also derived from the CFL approach, are introduced as an objective qualitative comparison nomenclature. We apply HAP to the analysis of 24 hours of frequently sampled pulsatile cortisol hormone data, which has known analysis challenges, from 14 healthy women. HAP analysis generated results in seconds and produced dozens of figures for each participant. The results quantify the observed qualitative features of cortisol data as a series of pulse clusters, each consisting of one or more embedded pulses, and identify two ultradian phenotypes in this dataset. HAP analysis is designed to be robust to individual differences and to missing data and may be applied to other pulsatile hormones. Future work can extend HAP analysis to other time-series data types, including oscillatory and other periodic physiological signals. PMID:25184442
emphasis on the challenges that faced compilers, and possible solutions. It is assumed that some of .... informants. The researchers and compilers of the Ndebele language corpus had foreseen some of these ..... ence of particular software systems," says Kennedy (1998: 82), "the Standard. Generalised Mark-up Language ...
Arbib, Michael A
The approach to language evolution suggested here focuses on three questions: How did the human brain evolve so that humans can develop, use, and acquire languages? How can the evolutionary quest be informed by studying brain, behavior, and social interaction in monkeys, apes, and humans? How can computational modeling advance these studies? I hypothesize that the brain is language ready in that the earliest humans had protolanguages but not languages (i.e., communication systems endowed with rich and open-ended lexicons and grammars supporting a compositional semantics), and that it took cultural evolution to yield societies (a cultural constructed niche) in which language-ready brains could become language-using brains. The mirror system hypothesis is a well-developed example of this approach, but I offer it here not as a closed theory but as an evolving framework for the development and analysis of conflicting subhypotheses in the hope of their eventual integration. I also stress that computational modeling helps us understand the evolving role of mirror neurons, not in and of themselves, but only in their interaction with systems "beyond the mirror." Because a theory of evolution needs a clear characterization of what it is that evolved, I also outline ideas for research in neurolinguistics to complement studies of the evolution of the language-ready brain. A clear challenge is to go beyond models of speech comprehension to include sign language and models of production, and to link language to visuomotor interaction with the physical and social world.
Finin, Timothy; Mayfield, James; Grosof, Benjamin
...: exploring and evaluating how semantic web technology can be integrated into and used by agent based systems, developing techniques for building information retrieval systems using semantic web data...
Although going on the ground with pupils remains the best way to understand the geologic structure of a deposit, it is very difficult to bring them in a mining extraction site and it is impossible to explore whole regions in search of these resources. For those reasons the KML (with the Google earth interface) is a very complete tool for teaching geosciences. Simple and intuitive, its handling is quickly mastered by the pupils, it also allows the teachers to validate skills for IT certificates. It allows the use of KML files stemming from online banks, from personal productions of the teacher or from pupils' works. These tools offer a global approach in 3D as well as a geolocation-based access to any type of geological data. The resource on which I built this KML is taught in the curriculum of the 3 years of French high school, it is methane hydrate. This non conventional hydrocarbon molecule enters in this vague border between mineral an organic matter (as phosphate deposits). It has become for over ten year the subject of the race for the exploitation of the gas hydrates fields in order to try to supply to the world demand. The methane hydrate fields are very useful and interesting to study the 3 majors themes of geological resource: the exploration, the exploitation and the risks especially for environments and populations. The KML which I propose allows the pupils to put itself in the skin of a geologist in search of deposits or on the technician who is going to extract the resource. It also allows them to evaluate the risks connected to the effect of tectonics activity or climatic changes on the natural or catastrophic releasing of methane and its role in the increase of the greenhouse effect. This KML associated to plenty of pedagogic activities is directly downloadable for teachers at http://eduterre.ens-lyon.fr/eduterre-usages/actualites/methane/.
Finin, Timothy; Mayfield, James; Grosof, Benjamin
The UMBC lead DAML project began with the goal to design and prototype critical software components enabling developers to create intelligent software agents capable of understanding and processing...
...) technology and the challenges the federal government faces in implementing it. XML is a flexible, nonproprietary set of standards designed to facilitate the exchange of information among disparate computer systems, using the Internet's protocols...
Hillah, L. M.; Kindler, Ekkart; Kordon, F.
ISO/IEC 15909 is an International Standard that is concerned with the high-level Petri nets. Part 1 defines the concepts, the mathematics, and the graphical notation -- and some variants of high-level nets. Part 2 of ISO/IEC 15909, which is currently under the last ballot to be an International......, it is used in a setting restricted to high-level nets and a simple version of Petri nets called Place/Transition-Systems. Future parts, of PNML will use the generality of PNML and also standardise some of its other concepts. For example, it is planned that Part 3 will define a module concepts known from...... modular PNML and will make the concept for defining new Petri net types explicit. In this paper, discuss PNML, its relation to ISO/IEC 15909 and the main ideas for the future extensions of PNML and its standardisation in Part 3 of ISO/IEC 15909-2....
S. Pemberton (Steven); not CWI et al
textabstractThis specification defines XHTML 1.0, a reformulation of HTML 4 as an XML 1.0 application, and three DTDs corresponding to the ones defined by HTML 4. The semantics of the elements and their attributes are defined in the W3C Recommendation for HTML 4. These semantics provide the
Almeida, Diogo; Poeppel, David; Corina, David
The human auditory system distinguishes speech-like information from general auditory signals in a remarkably fast and efficient way. Combining psychophysics and neurophysiology (MEG), we demonstrate a similar result for the processing of visual information used for language communication in users of sign languages. We demonstrate that the earliest visual cortical responses in deaf signers viewing American Sign Language (ASL) signs show specific modulations to violations of anatomic constraints that would make the sign either possible or impossible to articulate. These neural data are accompanied with a significantly increased perceptual sensitivity to the anatomical incongruity. The differential effects in the early visual evoked potentials arguably reflect an expectation-driven assessment of somatic representational integrity, suggesting that language experience and/or auditory deprivation may shape the neuronal mechanisms underlying the analysis of complex human form. The data demonstrate that the perceptual tuning that underlies the discrimination of language and non-language information is not limited to spoken languages but extends to languages expressed in the visual modality.
Almeida, Diogo; Poeppel, David; Corina, David
ABSTRACT The human auditory system distinguishes speech-like information from general auditory signals in a remarkably fast and efficient way. Combining psychophysics and neurophysiology (MEG), we demonstrate a similar result for the processing of visual information used for language communication in users of sign languages. We demonstrate that the earliest visual cortical responses in deaf signers viewing American Sign Language signs show specific modulations to violations of anatomic constraints that would make the sign either possible or impossible to articulate. These neural data are accompanied with a significantly increased perceptual sensitivity to the anatomical incongruity. The differential effects in the early visual evoked potentials arguably reflect an expectation-driven assessment of somatic representational integrity, suggesting that language experience and/or auditory deprivation may shape the neuronal mechanisms underlying the analysis of complex human form. The data demonstrate that the perceptual tuning that underlies the discrimination of language and non-language information is not limited to spoken languages but extends to languages expressed in the visual modality. PMID:27135041
Rodriguez, Nicolas; Thomas, Alex; Watanabe, Leandro; Vazirabad, Ibrahim Y; Kofia, Victor; Gómez, Harold F; Mittag, Florian; Matthes, Jakob; Rudolph, Jan; Wrzodek, Finja; Netz, Eugen; Diamantikos, Alexander; Eichner, Johannes; Keller, Roland; Wrzodek, Clemens; Fröhlich, Sebastian; Lewis, Nathan E; Myers, Chris J; Le Novère, Nicolas; Palsson, Bernhard Ø; Hucka, Michael; Dräger, Andreas
JSBML, the official pure Java programming library for the Systems Biology Markup Language (SBML) format, has evolved with the advent of different modeling formalisms in systems biology and their ability to be exchanged and represented via extensions of SBML. JSBML has matured into a major, active open-source project with contributions from a growing, international team of developers who not only maintain compatibility with SBML, but also drive steady improvements to the Java interface and promote ease-of-use with end users. Source code, binaries and documentation for JSBML can be freely obtained under the terms of the LGPL 2.1 from the website http://sbml.org/Software/JSBML. More information about JSBML can be found in the user guide at http://sbml.org/Software/JSBML/docs/. firstname.lastname@example.org or email@example.com Supplementary data are available at Bioinformatics online. © The Author 2015. Published by Oxford University Press.
Myers, Chris J; Beal, Jacob; Gorochowski, Thomas E; Kuwahara, Hiroyuki; Madsen, Curtis; McLaughlin, James Alastair; Mısırlı, Göksel; Nguyen, Tramy; Oberortner, Ernst; Samineni, Meher; Wipat, Anil; Zhang, Michael; Zundel, Zach
A synthetic biology workflow is composed of data repositories that provide information about genetic parts, sequence-level design tools to compose these parts into circuits, visualization tools to depict these designs, genetic design tools to select parts to create systems, and modeling and simulation tools to evaluate alternative design choices. Data standards enable the ready exchange of information within such a workflow, allowing repositories and tools to be connected from a diversity of sources. The present paper describes one such workflow that utilizes, among others, the Synthetic Biology Open Language (SBOL) to describe genetic designs, the Systems Biology Markup Language to model these designs, and SBOL Visual to visualize these designs. We describe how a standard-enabled workflow can be used to produce types of design information, including multiple repositories and software tools exchanging information using a variety of data standards. Recently, the ACS Synthetic Biology journal has recommended the use of SBOL in their publications. © 2017 The Author(s); published by Portland Press Limited on behalf of the Biochemical Society.
Monge-Nájera, Julián; Ho, Yuh-Shan
The Revista de Biología Tropical / International Journal of Tropical Biology and Conservation, founded in 1953, publishes feature articles about tropical nature and is considered one of the leading journals in Latin America. This article analyzes document type, language, countries, institutions, citations and for the first time article lifespan, from 1976 through 2014. We analyzed 3 978 documents from the Science Citation Index Expanded. Articles comprised 88 % of the total production and had 3.7 citations on average, lower than reviews. Spanish and English articles were nearly equal in numbers and citation for English articles was only slightly higher. Costa Rica, Mexico, and the USA are the countries with more articles, and the leading institutions were Universidad de Costa Rica, Universidad Nacional, Universidad Nacional Autónoma de Mexico and Universidad de Oriente (Venezuela). The citation lifespan of articles is long, around 37 years. It is not surprising that Costa Rica, Mexico, and Venezuela lead in productivity and cooperation, because they are mostly covered by tropical ecosystems and share a common culture and a tradition of scientific cooperation. The same applies to the leading institutions, which are among the largest Spanish language universities in the neotropical region. American output can be explained by the regional presence of the Smithsonian Tropical Research Institute and the Organization for Tropical Studies. Tropical research does not have the rapid change typical of medical research, and for this reason, the impact factor misses most of citations for the Revista, which are made after the two-year window used by the Web of Science. This issue is especially damaging for the Revista because most journals that deal with tropical biology are never checked when citations are counted for by the Science Citation Index.
Li, Peter; Dada, Joseph O; Jameson, Daniel; Spasic, Irena; Swainston, Neil; Carroll, Kathleen; Dunn, Warwick; Khan, Farid; Malys, Naglis; Messiha, Hanan L; Simeonidis, Evangelos; Weichart, Dieter; Winder, Catherine; Wishart, Jill; Broomhead, David S; Goble, Carole A; Gaskell, Simon J; Kell, Douglas B; Westerhoff, Hans V; Mendes, Pedro; Paton, Norman W
The behaviour of biological systems can be deduced from their mathematical models. However, multiple sources of data in diverse forms are required in the construction of a model in order to define its components and their biochemical reactions, and corresponding parameters. Automating the assembly and use of systems biology models is dependent upon data integration processes involving the interoperation of data and analytical resources. Taverna workflows have been developed for the automated assembly of quantitative parameterised metabolic networks in the Systems Biology Markup Language (SBML). A SBML model is built in a systematic fashion by the workflows which starts with the construction of a qualitative network using data from a MIRIAM-compliant genome-scale model of yeast metabolism. This is followed by parameterisation of the SBML model with experimental data from two repositories, the SABIO-RK enzyme kinetics database and a database of quantitative experimental results. The models are then calibrated and simulated in workflows that call out to COPASIWS, the web service interface to the COPASI software application for analysing biochemical networks. These systems biology workflows were evaluated for their ability to construct a parameterised model of yeast glycolysis. Distributed information about metabolic reactions that have been described to MIRIAM standards enables the automated assembly of quantitative systems biology models of metabolic networks based on user-defined criteria. Such data integration processes can be implemented as Taverna workflows to provide a rapid overview of the components and their relationships within a biochemical system.
Full Text Available Studies about the relations between classroom discourse interactions and processes of teaching and learning show that science learning is related to a process structured by speech genres and ways of establishing semantic links between events, objects, and people. Accordingly, it has been emphasized that science education research needs to incorporate theories and methods developed for the interpretative analysis of discourse. This paper shows the heuristic power that an interpretative analysis of discourse based on Bakhtin’s theory of language can have in the investigation of meaning making in science education in multicultural contexts. With this purpose, we discuss here results obtained in the analysis of the discourse about “nature” or “natural world” of protestant Biology preservice teachers of a Brazilian university, produced in the context of semi-structured interviews.
Frank, Steven A
Human language emerged abruptly. Diverse body forms evolved suddenly. Seed-bearing plants spread rapidly. How do complex evolutionary innovations arise so quickly? Resolving alternative claims remains difficult. The great events of the past happened a long time ago. Cancer provides a model to study evolutionary innovation. A tumor must evolve many novel traits to become an aggressive cancer. I use what we know or could study about cancer to describe the key processes of innovation. In general, evolutionary systems form a hierarchy of recursive processes. Those recursive processes determine the rates at which innovations are generated, spread and transmitted. I relate the recursive processes to abrupt evolutionary innovation.
Full Text Available The use of digital learning resources creates an increasing need for semantic metadata, describing the whole resource, as well as parts of resources. Traditionally, schemas such as Text Encoding Initiative (TEI have been used to add semantic markup for parts of resources. This is not sufficient for use in a Ã¢Â€Âmetadata ecologyÃ¢Â€Â, where metadata is distributed, coherent to different Application Profiles, and added by different actors. A new methodology, where metadata is Ã¢Â€Âœpointed inÃ¢Â€Â as annotations, using XPointers, and RDF is proposed. A suggestion for how such infrastructure can be implemented, using existing open standards for metadata, and for the web is presented. We argue that such methodology and infrastructure is necessary to realize the decentralized metadata infrastructure needed for a Ã¢Â€Âœmetadata ecology".
Full Text Available The aim of the paper is to present of the possibilities of positioning and visual markup of historical cadastral maps onto Google maps using open source software. The corpus is stored in the Croatian State Archives in Zagreb, in the Maps Archive for Croatia and Slavonia. It is part of cadastral documentation that consists of cadastral material from the period of first cadastral survey conducted in the Kingdom of Croatia and Slavonia from 1847 to 1877, and which is used extensively according to the data provided by the customer service of the Croatian State Archives. User needs on the one side and the possibilities of innovative implementation of ICT on the other have motivated the development of the system which would use digital copies of original cadastral maps and connect them with systems like Google maps, and thus both protect the original materials and open up new avenues of research related to the use of originals. With this aim in mind, two cadastral map presentation models have been created. Firstly, there is a detailed display of the original, which enables its viewing using dynamic zooming. Secondly, the interactive display is facilitated through blending the cadastral maps with Google maps, which resulted in establishing links between the coordinates of the digital and original plans through transformation. The transparency of the original can be changed, and the user can intensify the visibility of the underlying layer (Google map or the top layer (cadastral map, which enables direct insight into parcel dynamics over a longer time-span. The system also allows for the mark-up of cadastral maps, which can lead to the development of the cumulative index of all terms found on cadastral maps. The paper is an example of the implementation of ICT for providing new services, strengthening cooperation with the interested public and related institutions, familiarizing the public with the archival material, and offering new possibilities for
I am particularly happy that the Academy is bringing out this document by Professor M S. Valiathan on Ayurvedic Biology. It is an effort to place before the scientific community, especially that of India, the unique scientific opportunities that arise out of viewing Ayurveda from the perspective of contemporary science, its tools ...
Palafox, Benjamin; Patouillard, Edith; Tougher, Sarah; Goodman, Catherine; Hanson, Kara; Kleinschmidt, Immo; Torres Rueda, Sergio; Kiefer, Sabine; O'Connell, Kate; Zinsou, Cyprien; Phok, Sochea; Akulayi, Louis; Arogundade, Ekundayo; Buyungo, Peter; Mpasela, Felton; Poyer, Stephen; Chavasse, Desmond
The private for-profit sector is an important source of treatment for malaria. However, private patients face high prices for the recommended treatment for uncomplicated malaria, artemisinin combination therapies (ACTs), which makes them more likely to receive cheaper, less effective non-artemisinin therapies (nATs). This study seeks to better understand consumer antimalarial prices by documenting and exploring the pricing behaviour of retailers and wholesalers. Using data collected in 2009-10, we present survey estimates of antimalarial retail prices, and wholesale- and retail-level price mark-ups from six countries (Benin, Cambodia, the Democratic Republic of Congo, Nigeria, Uganda and Zambia), along with qualitative findings on factors affecting pricing decisions. Retail prices were lowest for nATs, followed by ACTs and artemisinin monotherapies (AMTs). Retailers applied the highest percentage mark-ups on nATs (range: 40% in Nigeria to 100% in Cambodia and Zambia), whereas mark-ups on ACTs (range: 22% in Nigeria to 71% in Zambia) and AMTs (range: 22% in Nigeria to 50% in Uganda) were similar in magnitude, but lower than those applied to nATs. Wholesale mark-ups were generally lower than those at retail level, and were similar across antimalarial categories in most countries. When setting prices wholesalers and retailers commonly considered supplier prices, prevailing market prices, product availability, product characteristics and the costs related to transporting goods, staff salaries and maintaining a property. Price discounts were regularly used to encourage sales and were sometimes used by wholesalers to reward long-term customers. Pricing constraints existed only in Benin where wholesaler and retailer mark-ups are regulated; however, unlicensed drug vendors based in open-air markets did not adhere to the pricing regime. These findings indicate that mark-ups on antimalarials are reasonable. Therefore, improving ACT affordability would be most readily
Klarlund, Nils; Møller, Anders; Schwartzbach, Michael Ignatieff
XML (Extensible Markup Language), a linear syntax for trees, has gathered a remarkable amount of interest in industry. The acceptance of XML opens new venues for the application of formal methods such as specification of abstract syntax tree sets and tree transformations. A user domain may...... be specified as a set of trees. For example, XHTML is a user domain corresponding to a set of XML documents that make sense as hypertext. A notation for defining such a set of XML trees is called a schema language. We believe that a useful schema notation must identify most of the syntactic requirements...... to the DSD (Document Structure Description) notation as our bid on how to meet these requirements. The DSD notation was inspired by industrial needs. We show how DSDs help manage aspects of complex XML software through a case study about interactive voice response systems, i.e., automated telephone answering...
Haddad, Peiman; Cheung, Fred; Pond, Gregory; Easton, Debbie; Cops, Frederick; Bezjak, Andrea; McLean, Michael; Levin, Wilfred; Billingsley, Susan; Williams, Diane; Wong, Rebecca
Purpose To evaluate the impact of computed tomographic (CT) planning in comparison to clinical mark-up (CM) for palliative radiation of chest wall metastases. Methods and Materials In patients treated with CM for chest wall bone metastases (without conventional simulation/fluoroscopy), two consecutive planning CT scans were acquired with and without an external marker to delineate the CM treatment field. The two sets of scans were fused for evaluation of clinical tumor volume (CTV) coverage by the CM technique. Under-coverage was defined as the proportion of CTV not covered by the CM 80% isodose. Results Twenty-one treatments (ribs 17, sternum 2, and scapula 2) formed the basis of our study. Due to technical reasons, comparable data between CM and CT plans were available for 19 treatments only. CM resulted in a mean CTV under-coverage of 36%. Eleven sites (58%) had an under-coverage of >20%. Mean volume of normal tissues receiving ≥80% of the dose was 5.4% in CM and 9.3% in CT plans (p = 0.017). Based on dose-volume histogram comparisons, CT planning resulted in a change of treatment technique from direct apposition to a tangential pair in 7 of 19 cases. Conclusions CT planning demonstrated a 36% under-coverage of CTV with CM of ribs and chest wall metastases
Waning, Brenda; Maddix, Jason; Soucy, Lyne
Numerous not-for-profit pharmacies have been created to improve access to medicines for the poor, but many have failed due to insufficient financial planning and management. These pharmacies are not well described in health services literature despite strong demand from policy makers, implementers, and researchers. Surveys reporting unaffordable medicine prices and high mark-ups have spurred efforts to reduce medicine prices, but price reduction goals are arbitrary in the absence of information on pharmacy costs, revenues, and profit structures. Health services research is needed to develop sustainable and "reasonable" medicine price goals and strategic initiatives to reach them. We utilized cost accounting methods on inventory and financial information obtained from a not-for-profit rural pharmacy network in mountainous Kyrgyzstan to quantify costs, revenues, profits and medicine mark-ups during establishment and maintenance periods (October 2004-December 2007). Twelve pharmacies and one warehouse were established in remote Kyrgyzstan with ups. Medicine mark-ups needed for sustainability were greater than originally envisioned by network administration. In 2005, 55%, 35%, and 10% of the network's top 50 products revealed mark-ups of 100%, respectively. Annual mark-ups increased dramatically each year to cover increasing recurrent costs, and by 2007, only 19% and 46% of products revealed mark-ups of ups > 100%. 2007 medicine mark-ups varied substantially across these products, ranging from 32% to 244%. Mark-ups needed to sustain private pharmacies would be even higher in the absence of government subsidies. Pharmacy networks can be established in hard-to-reach regions with little funding using public-private partnership, resource-sharing models. Medicine prices and mark-ups must be interpreted with consideration for regional costs of business. Mark-ups vary dramatically across medicines. Some mark-ups appear "excessive" but are likely necessary for pharmacy
Shirai, M. [Central Research Institute of Electric Power Industry, Tokyo (Japan)
This paper introduces the new estimation method of a mark-up rate (ratio of cost and limited expenses) for each industry reported by Nishimura and Shirai (in 1998) and the result of application of it to the industry in Japan. The problem (generation of short-term fixed cost or establishment of short-term economy) that occurs as a barrier in the application of a primary and homogeneous neoclassical production function is solved by assuming the short-term fixity of production organization. Moreover, the compatibility with study (indicating that the production function becomes a primary and homogeneous function if the short-term adjustment of production organization is completed) by Basu can also be maintained. A short-term production function obtained when this assumption is formulated is introduced in this case. Next, a regression expression for estimating the mark-up rate using a short-term production function is given. The mark-up rate was estimated for 22 types of industries by using the data between 1965 and 1995. The result shows that the industry to which estimation can be applied is significantly in the imperfect competition state. 13 refs., 1 fig. 1 tab.
Inigo San Gil; Wade Sheldon; Tom Schmidt; Mark Servilla; Raul Aguilar; Corinna Gries; Tanya Gray; Dawn Field; James Cole; Jerry Yun Pan; Giri Palanisamy; Donald Henshaw; Margaret O' Brien; Linda Kinkel; Kathrine McMahon; Renzo Kottmann; Linda Amaral-Zettler; John Hobbie; Philip Goldstein; Robert P. Guralnick; James Brunt; William K. Michener
The Genomic Standards Consortium (GSC) invited a representative of the Long-Term Ecological Research (LTER) to its fifth workshop to present the Ecological Metadata Language (EML) metadata standard and its relationship to the Minimum Information about a Genome/Metagenome Sequence (MIGS/MIMS) and its implementation, the Genomic Contextual Data Markup Language (GCDML)....
Lefever, S.; Hellemans, J.; Pattyn, F.; Przybylski, D.R.; Taylor, C.; Geurts, R.; Untergasser, A.; Vandesompele, J.
The XML-based Real-Time PCR Data Markup Language (RDML) has been developed by the RDML consortium (http://www.rdml.org) to enable straightforward exchange of qPCR data and related information between qPCR instruments and third party data analysis software, between colleagues and collaborators and
Nagasaki, Masao; Saito, Ayumu; Jeong, Euna; Li, Chen; Kojima, Kaname; Ikeda, Emi; Miyano, Satoru
Cell Illustrator is a software platform for Systems Biology that uses the concept of Petri net for modeling and simulating biopathways. It is intended for biological scientists working at bench. The latest version of Cell Illustrator 4.0 uses Java Web Start technology and is enhanced with new capabilities, including: automatic graph grid layout algorithms using ontology information; tools using Cell System Markup Language (CSML) 3.0 and Cell System Ontology 3.0; parameter search module; high-performance simulation module; CSML database management system; conversion from CSML model to programming languages (FORTRAN, C, C++, Java, Python and Perl); import from SBML, CellML, and BioPAX; and, export to SVG and HTML. Cell Illustrator employs an extension of hybrid Petri net in an object-oriented style so that biopathway models can include objects such as DNA sequence, molecular density, 3D localization information, transcription with frame-shift, translation with codon table, as well as biochemical reactions.
Bae, Kyoung-Il; Kim, Jung-Hyun; Huh, Soon-Young
Discusses process information sharing among participating organizations in a virtual enterprise and proposes a federated process framework and system architecture that provide a conceptual design for effective implementation of process information sharing supporting the autonomy and agility of the organizations. Develops the framework using an…
Rinaldi, Fabio; Ellendorff, Tilia Renate; Madan, Sumit; Clematide, Simon; van der Lek, Adrian; Mevissen, Theo; Fluck, Juliane
Automatic extraction of biological network information is one of the most desired and most complex tasks in biological and medical text mining. Track 4 at BioCreative V attempts to approach this complexity using fragments of large-scale manually curated biological networks, represented in Biological Expression Language (BEL), as training and test data. BEL is an advanced knowledge representation format which has been designed to be both human readable and machine processable. The specific goal of track 4 was to evaluate text mining systems capable of automatically constructing BEL statements from given evidence text, and of retrieving evidence text for given BEL statements. Given the complexity of the task, we designed an evaluation methodology which gives credit to partially correct statements. We identified various levels of information expressed by BEL statements, such as entities, functions, relations, and introduced an evaluation framework which rewards systems capable of delivering useful BEL fragments at each of these levels. The aim of this evaluation method is to help identify the characteristics of the systems which, if combined, would be most useful for achieving the overall goal of automatically constructing causal biological networks from text. © The Author(s) 2016. Published by Oxford University Press.
Testing a model of science process skills acquisition: An interaction with parents' education, preferred language, gender, science attitude, cognitive development, academic ability, and biology knowledge
Germann, Paul J.
Path analysis techniques were used to test a hypothesized structural model of direct and indirect causal effects of student variables on science process skills. The model was tested twice using data collected at the beginning and end of the school year from 67 9th- and 10th-grade biology students who lived in a rural Franco-American community in New England. Each student variable was found to have significant effects, accounting for approximately 80% of the variance in science process skills achievement. Academic ability, biology knowledge, and language preference had significant direct effects. There were significant mediated effects by cognitive development, parents' education, and attitude toward science in school. The variables of cognitive development and academic ability had the greatest total effects on science process skills. Implications for practitioners and researchers are discussed.
In common with many fields, including astronomy, a vast number of software tools for computational modeling and simulation are available today in systems biology. This wealth of resources is a boon to researchers, but it also presents interoperability problems. Despite working with different software tools, researchers want to disseminate their work widely as well as reuse and extend the models of other researchers. This situation led in the year 2000 to an effort to create a tool-independent, machine-readable file format for representing models: SBML, the Systems Biology Markup Language. SBML has since become the de facto standard for its purpose. Its success and general approach has inspired and influenced other community-oriented standardization efforts in systems biology. Open standards are essential for the progress of science in all fields, but it is often difficult for academic researchers to organize successful community-based standards. I draw on personal experiences from the development of SBML and summarize some of the lessons learned, in the hope that this may be useful to other groups seeking to develop open standards in a community-oriented fashion.
Suhonen, Eira; Sajaniemi, Nina K.; Alijoki, Alisa; Nislin, Mari A.
We aimed to investigate stress response regulation, temperament, cognitive and language abilities and family SES in children who entered kindergarten before two years of age. Whilst childrens stress regulatory systems are vulnerable to environmental influences little is known about how temperament and family characteristics impact on stress…
a discussion about the structure of hypertext expression languages. The operations have been chosen in agreement with what is strongly suggested, but not defined, by the HTML-standard. The HTEL-interpreter can be used for cgi-programs, i.e. to describe reactions when data from a `form' in an HTML-document has...... been submitted.A special tool has been used to build the HTEL-interpreter, as an example belonging a family of interpreters for domain specific languages. Members of that family have characteristics that are closely related to structural patterns found in the mark-ups of HTML. HTEL should also be seen......In general, an expression language provides a means to indicate non-constant values in expressions. It includes operations to combine values, but these will normally disappear when the expression is evaluated.HTEL is an expression language to produce HTML-documents. It is presented to stimulate...
In general, an expression language provides a means to indicate non-constant values in expressions. It includes operations to combine values, but these will normally disappear when the expression is evaluated.HTEL is an expression language to produce HTML-documents. It is presented to stimulate...... a discussion about the structure of hypertext expression languages. The operations have been chosen in agreement with what is strongly suggested, but not defined, by the HTML-standard. The HTEL-interpreter can be used for cgi-programs, i.e. to describe reactions when data from a `form' in an HTML-document has...... been submitted.A special tool has been used to build the HTEL-interpreter, as an example belonging a family of interpreters for domain specific languages. Members of that family have characteristics that are closely related to structural patterns found in the mark-ups of HTML. HTEL should also be seen...
Meystre, Stephanie; Haug, Peter J
We are developing tools to help maintain a complete, accurate and timely problem list within a general purpose Electronic Medical Record system. As a part of this project, we have designed a system to automatically retrieve medical problems from free-text documents. Here we describe an information model based on XML (eXtensible Markup Language) and compliant with the CDA (Clinical Document Architecture). This model is used to ease the exchange of clinical data between the Natural Language Understanding application that retrieves potential problems from narrative document, and the problem list management application.
Herrgård, Markus J; Swainston, Neil; Dobson, Paul; Dunn, Warwick B; Arga, K Yalçin; Arvas, Mikko; Blüthgen, Nils; Borger, Simon; Costenoble, Roeland; Heinemann, Matthias; Hucka, Michael; Le Novère, Nicolas; Li, Peter; Liebermeister, Wolfram; Mo, Monica L; Oliveira, Ana Paula; Petranovic, Dina; Pettifer, Stephen; Simeonidis, Evangelos; Smallbone, Kieran; Spasić, Irena; Weichart, Dieter; Brent, Roger; Broomhead, David S; Westerhoff, Hans V; Kirdar, Betül; Penttilä, Merja; Klipp, Edda; Palsson, Bernhard Ø; Sauer, Uwe; Oliver, Stephen G; Mendes, Pedro; Nielsen, Jens; Kell, Douglas B
Genomic data allow the large-scale manual or semi-automated assembly of metabolic network reconstructions, which provide highly curated organism-specific knowledge bases. Although several genome-scale network reconstructions describe Saccharomyces cerevisiae metabolism, they differ in scope and content, and use different terminologies to describe the same chemical entities. This makes comparisons between them difficult and underscores the desirability of a consolidated metabolic network that collects and formalizes the 'community knowledge' of yeast metabolism. We describe how we have produced a consensus metabolic network reconstruction for S. cerevisiae. In drafting it, we placed special emphasis on referencing molecules to persistent databases or using database-independent forms, such as SMILES or InChI strings, as this permits their chemical structure to be represented unambiguously and in a manner that permits automated reasoning. The reconstruction is readily available via a publicly accessible database and in the Systems Biology Markup Language (http://www.comp-sys-bio.org/yeastnet). It can be maintained as a resource that serves as a common denominator for studying the systems biology of yeast. Similar strategies should benefit communities studying genome-scale metabolic networks of other organisms.
needed. In addition, it will be important to conduct empirical evaluation of the applicability and benefits of OWL-S in developing and managing service...Sycara, and T. Nishimura, "Towards a Semantic Web Ecommerce ," in Proceedings of 6th Conference on Business Information Systems (BIS2003), Colorado...various Web services standardization efforts is the vision of the enormous benefit to be had by achieving reliable, ubiquitous software
.... This work synthesizes air planning data messages, Air Tasking Order(ATO) data messages, written in XML and based upon the USMTF standard, and displays these messages as a three-dimensional (3D...
consider the pros and cons of the two primary ways applications can be designed and programmed: (1) native applications and (2) applications using HTML5 ...content and functionality of the application. HTML5 is considered the fifth iteration, or version, of Hypertext Markup Language (HTML) and is used...mobile devices, etc.). HTML5 builds on the previous coding standards with the addition of certain improvements. One of the improvements most
Tang, Wenxi; Xie, Jing; Lu, Yijuan; Liu, Qizhi; Malone, Daniel; Ma, Aixia
The State Council of China requires that all urban public hospitals must eliminate drug markups by September 2017, and that hospital drugs must be sold at the purchase price. Nanjing-one of the first provincial capital cities to implement the reform-is studied to evaluate the effects of the comprehensive reform on drug prices in public hospitals, and to explore differential compensation plans. Sixteen hospitals were selected, and financial data were collected over the 48-month period before the reform and for 12 months after the reform. An analysis was carried out using a simple linear interrupted time series model. The average difference ratio of drug surplus fell 13.39% after the reform, and the drug markups were basically eliminated. Revenue from medical services showed a net growth of 28.25%. The overall compensation received from government financial budget and medical service revenue growth was 103.69% for the loss from policy-permitted 15% markup sales, and 116.48% for the net loss. However, there were large differences in compensation levels at different hospitals, ranging from -21.92% to 413.74% by medical services revenue growth, causing the combined rate of both financial and service compensation to vary from 28.87-413.74%, There was a significant positive correlation between the services compensation rate and the proportion of medical service revenue (p revenue. Nanjing's pricing and compensation reform has basically achieved the policy targets of eliminating the drug markups, promoting the growth of medical services revenue, and adjusting the structure of medical revenue. However, the growth rate of service revenue of hospitals varied significantly from one another. Nanjing's reform represents successful pricing and compensation reform in Chinese urban public hospitals. It is recommended that a differentiated and dynamic compensation plan should be established in accordance with the revenue structure of different hospitals.
Gilberto Tadeu Lima
Full Text Available Elabora-se um modelo macrodinâmico pós-keynesiano de utilização da capacidade, distribuição e inflação por conflito, no qual a oferta de moeda de crédito é endógena. A taxa nominal de juros é determinada pela aplicação de um mark-up sobre a taxa básica fixada pela autoridade monetária. Ao longo do tempo, o mark-up bancário varia com a taxa de lucro sobre o capital físico, enquanto a taxa básica varia com excessos de demanda que não são acomodáveis pela utilização da capacidade. São analisados os casos em que a demanda é suficiente ou não para gerar a plena utilização da capacidade.It is developed a post-keynesian macrodynamic model of capacity utilization, distribution and conflict inflation, in which the supply of credit-money is endogenous. Nominal interest rate is determined by banks as a markup over the base rate, which is set by the monetary authority. Over time, banking markup varies with firms' profit rate on physical capital, while the base rate rises with any excess demand when capacity is fully utilized. The behavior of the economy is analyzed for the cases in which demand is or is not enough to ensure full capacity utilization.
Biologie und Fremdsprachenunterricht. Das Prinzip der Einsprachigkeit im Lichte biologischer Erkenntnisse ueber Denken und Lernen (Biology and Foreign Language Teaching. The Monolingual Principle in the Light of Biological Findings concerning Thinking and Learning).
Draws upon recent publications dealing with brain function (particularly F. Vester, "Denken, Lernen, Vergessen", Munich, 1978) for ideas for foreign language teaching. These include constant use of the foreign language in the classroom, frequent repetition, and avoidance of false associations by explanation in the native language.…
jbiosci. J. Biosci. 30(1), February 2005, ... communication systems in that it permits the creation of limitless representations by the creative ... on whether the learner was exposed to English or to. Marathi (e.g. Hall and Waxman 2004). Learning the ...
Full Text Available BACKGROUND: A microorganism is a complex biological system able to preserve its functional features against external perturbations and the ability of the living systems to oppose to these external perturbations is defined "robustness". The antibiotic resistance, developed by different bacteria strains, is a clear example of robustness and of ability of the bacterial system to acquire a particular functional behaviour in response to environmental changes. In this work we have modeled the whole mechanism essential to the methicillin-resistance through a systems biology approach. The methicillin is a beta-lactamic antibiotic that act by inhibiting the penicillin-binding proteins (PBPs. These PBPs are involved in the synthesis of peptidoglycans, essential mesh-like polymers that surround cellular enzymes and are crucial for the bacterium survival. METHODOLOGY: The network of genes, mRNA, proteins and metabolites was created using CellDesigner program and the data of molecular interactions are stored in Systems Biology Markup Language (SBML. To simulate the dynamic behaviour of this biochemical network, the kinetic equations were associated with each reaction. CONCLUSIONS: Our model simulates the mechanism of the inactivation of the PBP by methicillin, as well as the expression of PBP2a isoform, the regulation of the SCCmec elements (SCC: staphylococcal cassette chromosome and the synthesis of peptidoglycan by PBP2a. The obtained results by our integrated approach show that the model describes correctly the whole phenomenon of the methicillin resistance and is able to respond to the external perturbations in the same way of the real cell. Therefore, this model can be useful to develop new therapeutic approaches for the methicillin control and to understand the general mechanism regarding the cellular resistance to some antibiotics.
Surveys developments in language revitalization and language death. Focusing on indigenous languages, discusses the role and nature of appropriate linguistic documentation, possibilities for bilingual education, and methods of promoting oral fluency and intergenerational transmission in affected languages. (Author/VWL)
Hung, Nguyen Manh, Ed.
This volume contains 32 biology self-study learning packets designed primarily for Indochinese students in grades 9 to 12. The materials could be used by "English as a Second Language" teachers who may/may not speak one of the Indochinese languages, or by mainstream teachers who have a number of low-English-proficiency Indochinese students in…
Nguyen, Andrew Van; Avrin, David E.; Tellis, Wyatt M.; Andriole, Katherine P.; Arenson, Ronald L.
Common object request broker architecture (CORBA) is a method for invoking distributed objects across a network. There has been some activity in applying this software technology to Digital Imaging and Communications in Medicine (DICOM), but no documented demonstration of how this would actually work. We report a CORBA demonstration that is functionally equivalent and in some ways superior to the DICOM communication protocol. In addition, in and outside of medicine, there is great interest in...
Cochella, C; Lauman, J R; Goede, P; Harnsberger, H R; Katzman, G L
It is challenging to remotely share generic medical case information without an agreed upon definition of a medical digital teaching file (DTF). By utilizing an application of the extensible markup language (XML) called web-distributed data exchange (WDDX) along with an agreed upon WDDX structure, it is technically easy to share or syndicate medical case DTFs across computing environments that use different information models and computer languages. Thus, this easily implemented technology offers us an immediately available means to share and increase the value of scientific knowledge.
Gómez, David Maximiliano; Berent, Iris; Benavides-Varela, Silvia; Bion, Ricardo A. H.; Cattarossi, Luigi; Nespor, Marina; Mehler, Jacques
The evolution of human languages is driven both by primitive biases present in the human sensorimotor systems and by cultural transmission among speakers. However, whether the design of the language faculty is further shaped by linguistic biological biases remains controversial. To address this question, we used near-infrared spectroscopy to examine whether the brain activity of neonates is sensitive to a putatively universal phonological constraint. Across languages, syllables like blif are preferred to both lbif and bdif. Newborn infants (2–5 d old) listening to these three types of syllables displayed distinct hemodynamic responses in temporal-perisylvian areas of their left hemisphere. Moreover, the oxyhemoglobin concentration changes elicited by a syllable type mirrored both the degree of its preference across languages and behavioral linguistic preferences documented experimentally in adulthood. These findings suggest that humans possess early, experience-independent, linguistic biases concerning syllable structure that shape language perception and acquisition. PMID:24706790
Australia has a language paradox: great richness and great poverty of language resources. Despite its many cultures and immigrant groups, Australia emphasizes English-language assimilation and thereby endangers its chances for durable multilingualism. (MSE)
We study bigraphs as a foundation for practical formal languages and the problem of simulating such bigraphical languages. The theory of bigraphs is a foundational, graphical model of concurrent systems focusing on mobility and connectivity. It is a meta-model in the sense that it is parametrized...... for practical formal languages. However, while direct models of many process calculi have been constructed, it is unclear how suitable bigraphs are for more practical formal languages. Also, the generality of bigraphs comes at a price of complexity in the theory and simulation of bigraphical models is non......-trivial. A key problem is that of matching: deciding if and how a reaction rule applies to a bigraph. In this dissertation, we study bigraphs and their simulation for two types of practical formal languages: programming languages and languages for cell biology. First, we study programming languages and binding...
Reviews and discusses the following books: "Language Death," by David Crystal; "The Green Book of Language Revitalization in Practice," by Leanne Hinton; and "Vanishing Voices of the World's Languages," by David Nettle. (Author/VWL)
Gong, Tao; Shuai, Lan
Memory is essential to many cognitive tasks including language. Apart from empirical studies of memory effects on language acquisition and use, there lack sufficient evolutionary explorations on whether a high level of memory capacity is prerequisite for language and whether language origin could influence memory capacity. In line with evolutionary theories that natural selection refined language-related cognitive abilities, we advocated a coevolution scenario between language and memory capacity, which incorporated the genetic transmission of individual memory capacity, cultural transmission of idiolects, and natural and cultural selections on individual reproduction and language teaching. To illustrate the coevolution dynamics, we adopted a multi-agent computational model simulating the emergence of lexical items and simple syntax through iterated communications. Simulations showed that: along with the origin of a communal language, an initially-low memory capacity for acquired linguistic knowledge was boosted; and such coherent increase in linguistic understandability and memory capacities reflected a language-memory coevolution; and such coevolution stopped till memory capacities became sufficient for language communications. Statistical analyses revealed that the coevolution was realized mainly by natural selection based on individual communicative success in cultural transmissions. This work elaborated the biology-culture parallelism of language evolution, demonstrated the driving force of culturally-constituted factors for natural selection of individual cognitive abilities, and suggested that the degree difference in language-related cognitive abilities between humans and nonhuman animals could result from a coevolution with language.
Evans, Stephanie; Alden, Kieran; Cucurull-Sanchez, Lourdes; Larminie, Christopher; Coles, Mark C; Kullberg, Marika C; Timmis, Jon
A calibrated computational model reflects behaviours that are expected or observed in a complex system, providing a baseline upon which sensitivity analysis techniques can be used to analyse pathways that may impact model responses. However, calibration of a model where a behaviour depends on an intervention introduced after a defined time point is difficult, as model responses may be dependent on the conditions at the time the intervention is applied. We present ASPASIA (Automated Simulation Parameter Alteration and SensItivity Analysis), a cross-platform, open-source Java toolkit that addresses a key deficiency in software tools for understanding the impact an intervention has on system behaviour for models specified in Systems Biology Markup Language (SBML). ASPASIA can generate and modify models using SBML solver output as an initial parameter set, allowing interventions to be applied once a steady state has been reached. Additionally, multiple SBML models can be generated where a subset of parameter values are perturbed using local and global sensitivity analysis techniques, revealing the model's sensitivity to the intervention. To illustrate the capabilities of ASPASIA, we demonstrate how this tool has generated novel hypotheses regarding the mechanisms by which Th17-cell plasticity may be controlled in vivo. By using ASPASIA in conjunction with an SBML model of Th17-cell polarisation, we predict that promotion of the Th1-associated transcription factor T-bet, rather than inhibition of the Th17-associated transcription factor RORγt, is sufficient to drive switching of Th17 cells towards an IFN-γ-producing phenotype. Our approach can be applied to all SBML-encoded models to predict the effect that intervention strategies have on system behaviour. ASPASIA, released under the Artistic License (2.0), can be downloaded from http://www.york.ac.uk/ycil/software.
White, Lana; Maylath, J. Bruce; Adams, Anthony; Couzijn, Michel
Language Awareness: A History and Implementations offers teachers of mother tongue and foreign languages a view of the beginnings and the ramifications of the language-teaching movement called Language Awareness. The philosophy held in common among the teachers in this international movement is
The following sections are included: * Definition of Dynamical Languages * Distinct Excluded Blocks * Definition and Properties * L and L″ in Chomsky Hierarchy * A Natural Equivalence Relation * Symbolic Flows * Symbolic Flows and Dynamical Languages * Subshifts of Finite Type * Sofic Systems * Graphs and Dynamical Languages * Graphs and Shannon-Graphs * Transitive Languages * Topological Entropy
Mengi V. Ondar
Full Text Available Contemporary information technologies and mathematical modelling has made creating corpora of natural languages significantly easier. A corpus is an information and reference system based on a collection of digitally processed texts. A corpus includes various written and oral texts in the given language, a set of dictionaries and markup – information on the properties of the text. It is the presence of the markup which distinguishes a corpus from an electronic library. At the moment, national corpora are being set up for many languages of the Russian Federation, including those of the Turkic peoples. Faculty members, postgraduate and undergraduate students at Tuvan State University and Siberian Federal University are working on the National corpus of Tuvan language. This article describes the structure of a dictionary entry in the National corpus of Tuvan language. The corpus database comprises the following tables: MAIN – the headword table, RUS, ENG, GER — translations of the headword into three languages, MORPHOLOGY — the table containing morphological data on the headword. The database is built in Microsoft Office Access. Working with the corpus dictionary includes the following functions: adding, editing and removing an entry, entry search (with transcription, setting and visualizing morphological features of a headword. The project allows us to view the corpus dictionary as a multi-structure entity with a complex hierarchical structure and a dictionary entry as its key component. The corpus dictionary we developed can be used for studying Tuvan language in its pronunciation, orthography and word analysis, as well as for searching for words and collocations in the texts included into the corpus.
Inigo, Gil San [University of New Mexico, Albuquerque; Servilla, Mark [ORNL; Brunt, James [University of New Mexico, Albuquerque; Michener, William [University of New Mexico, Albuquerque; Sheldon, Wade [University of Georgia, Athens, GA; Schmidt, Tom [Michigan State University, East Lansing; Cole, James [Michigan State University, East Lansing; Aguilar, Raul [Arizona State University; Gries, Corinna [Arizona State University; Gray, Tanya [NERC, Oxford, England; Field, Dawn [NERC, Oxford, England; Pan, Jerry Yun [ORNL; Palanisamy, Giri [ORNL; Henshaw, Donald [USDA Forest Service; O' Brien, Margaret [University of California, Santa Barbara
The Genomic Standards Consortium (GSC) invited a representative of the Long-Term Ecological Research (LTER) to its fifth workshop to present the Ecological Metadata Language (EML) metadata standard and its relationship to the Minimum Information about a Genome/Metagenome Sequence (MIGS/MIMS) and its implementation, the Genomic Contextual Data Markup Language (GCDML). The LTER is one of the top National Science Foundation (NSF) programs in biology since 1980, representing diverse ecosystems and creating long-term, interdisciplinary research, synthesis of information, and theory. The adoption of EML as the LTER network standard has been key to build network synthesis architectures based on high-quality standardized metadata. EML is the NSF-recognized metadata standard for LTER, and EML is a criteria used to review the LTER program progress. At the workshop, a potential crosswalk between the GCDML and EML was explored. Also, collaboration between the LTER and GSC developers was proposed to join efforts toward a common metadata cataloging designer's tool. The community adoption success of a metadata standard depends, among other factors, on the tools and trainings developed to use the standard. LTER's experience in embracing EML may help GSC to achieve similar success. A possible collaboration between LTER and GSC to provide training opportunities for GCDML and the associated tools is being explored. Finally, LTER is investigating EML enhancements to better accommodate genomics data, possibly integrating the GCDML schema into EML. All these action items have been accepted by the LTER contingent, and further collaboration between the GSC and LTER is expected.
Corballis, Michael C.
The mirror system provided a natural platform for the subsequent evolution of language. In nonhuman primates, the system provides for the understanding of biological action, and possibly for imitation, both prerequisites for language. I argue that language evolved from manual gestures, initially as a system of pantomime, but with gestures…
In response to the need for reliable results from natural language processing, this book presents an original way of decomposing a language(s) in a microscopic manner by means of intra/inter‑language norms and divergences, going progressively from languages as systems to the linguistic, mathematical and computational models, which being based on a constructive approach are inherently traceable. Languages are described with their elements aggregating or repelling each other to form viable interrelated micro‑systems. The abstract model, which contrary to the current state of the art works in int
Language and social skills are essential for intrapersonal and interpersonal functioning and quality of life. Since epilepsy impacts these important domains of individuals' functioning, understanding the psychosocial and biological factors involved in the relationship among epilepsy, language, and social skills has important theoretical and clinical implications. This review first describes the psychosocial and biological factors involved in the association between language and social behavior in children and in adults and their relevance for epilepsy. It reviews the findings of studies of social skills and the few studies conducted on the inter-relationship of language and social skills in pediatric and adult epilepsy. The paper concludes with suggested future research and clinical directions that will enhance early identification and treatment of epilepsy patients at risk for impaired language and social skills. Copyright © 2017 Elsevier Inc. All rights reserved.
by an alternative concept that more adequately describes the realities of what adherents of ‘parallel languages' can hope for. The new concept I have dubbed ‘complementary languages' (komplementærsproglighed). I will explain this concept in the following and contrast it both with ‘parallel languages...
Fitch, W Tecumseh
Human language is both highly diverse-different languages have different ways of achieving the same functional goals-and easily learnable. Any language allows its users to express virtually any thought they can conceptualize. These traits render human language unique in the biological world. Understanding the biological basis of language is thus both extremely challenging and fundamentally interesting. I review the literature on linguistic diversity and language universals, suggesting that an adequate notion of 'formal universals' provides a promising way to understand the facts of language acquisition, offering order in the face of the diversity of human languages. Formal universals are cross-linguistic generalizations, often of an abstract or implicational nature. They derive from cognitive capacities to perceive and process particular types of structures and biological constraints upon integration of the multiple systems involved in language. Such formal universals can be understood on the model of a general solution to a set of differential equations; each language is one particular solution. An explicit formal conception of human language that embraces both considerable diversity and underlying biological unity is possible, and fully compatible with modern evolutionary theory.
Recent work which combines methods from linguistics and evolutionary biology has been fruitful in discovering the history of major language families because of similarities in evolutionary processes. Such work opens up new possibilities for language research on previously unsolvable problems, especially in areas where information from other sources may be lacking. I use phylogenetic methods to investigate Tasmanian languages. Existing materials are so fragmentary that scholars have been unable to discover how many languages are represented in the sources. Using a clustering algorithm which identifies admixture, source materials representing more than one language are identified. Using the Neighbor-Net algorithm, 12 languages are identified in five clusters. Bayesian phylogenetic methods reveal that the families are not demonstrably related; an important result, given the importance of Tasmanian Aborigines for information about how societies have responded to population collapse in prehistory. This work provides insight into the societies of prehistoric Tasmania and illustrates a new utility of phylogenetics in reconstructing linguistic history. PMID:23015621
O'Grady, William; Hattori, Ryoko
Intergenerational transmission, the ultimate goal of language revitalization efforts, can only be achieved by (re)establishing the conditions under which an imperiled language can be acquired by the community's children. This paper presents a tutorial survey of several key points relating to language acquisition and maintenance in children,…
Full Text Available With a quasi-experimental design, this study aims to assess whether the Zero-markup Policy for Essential Drugs (ZPED reduces the medical expense for patients at county hospitals, the major healthcare provider in rural China.Data from Ningshan county hospital and Zhenping county hospital, China, include 2014 outpatient records and 9239 inpatient records. Quantitative methods are employed to evaluate ZPED. Both hospital-data difference-in-differences and individual-data regressions are applied to analyze the data from inpatient and outpatient departments.In absolute terms, the total expense per visit reduced by 19.02 CNY (3.12 USD for outpatient services and 399.6 CNY (65.60 USD for inpatient services. In relative terms, the expense per visit was reduced by 11% for both outpatient and inpatient services. Due to the reduction of inpatient expense, the estimated reduction of outpatient visits is 2% among the general population and 3.39% among users of outpatient services. The drug expense per visit dropped by 27.20 CNY (4.47 USD for outpatient services and 278.7 CNY (45.75 USD for inpatient services. The proportion of drug expense out of total expense per visit dropped by 11.73 percentage points in outpatient visits and by 3.92 percentage points in inpatient visits.Implementation of ZPED is a benefit for patients in both absolute and relative terms. The absolute monetary reduction of the per-visit inpatient expense is 20 times of that in outpatient care. According to cross-price elasticity, the substitution between inpatient and outpatient due to the change in inpatient price is small. Furthermore, given that the relative reductions are the same for outpatient and inpatient visits, according to relative thinking theory, the incentive to utilize outpatient or inpatient care attributed to ZPED is equivalent, regardless of the 20-times price difference in absolute terms.
... Home » Health Info » Voice, Speech, and Language Specific Language Impairment On this page: What is specific language ... percent of children in kindergarten. What is specific language impairment? Specific language impairment (SLI) is a language ...
Goold, Susan Dorr
Those who advocate higher out-of-pocket spending, especially high deductibles, to keep health care costs better controlled without losing quality use market language to talk about how people should think about health care. Consumers-that is, patients-should hunt for bargains. Clip coupons. Shop around. Patients need to have more "skin in the game." Consumer-patients will then choose more carefully and prudently and use less unnecessary health care. Unfailingly, "skin" refers to having money at stake. Usually, those arguing for high deductibles express dismay or frustration that patients do not face the full ("true") cost of the health services they receive. Unfortunately, a lack of price transparency, the need to unbundle bundled groups of services to discover total price, and the challenge of validly and reliably measuring and disclosing quality make shopping for health care a challenge for even the savviest patient. Urgency, fear, and sickness that impairs peak cognitive function and other aspects of emotionally laden decision-making, even when "shared" with a physician, add obstacles to coupon clipping and tire kicking. Who has more at stake in health decisions than patients? Whose flesh is literally, not just figuratively, at risk? © 2018 The Hastings Center.
The theory of fuzzy recognizable languages over bounded distributive lattices is presented as a paradigm of recognizable formal power series. Due to the idempotency properties of bounded distributive lattices, the equality of fuzzy recognizable languages is decidable, the determinization of multi-valued automata is effective, and a pumping lemma exists. Fuzzy recognizable languages over finite and infinite words are expressively equivalent to sentences of the multi-valued monadic second-order logic. Fuzzy recognizability over bounded ℓ-monoids and residuated lattices is briefly reported. The chapter concludes with two applications of fuzzy recognizable languages to real world problems in medicine.
Mousten, Birthe; Laursen, Anne Lise
-disciplinarily, because they work with both derivative and contributory approaches. Derivative, because specialized language retrieves its philosophy of science as well as methods from both the natural sciences, social sciences and humanistic sciences. Contributory because language results support the communication...... science fields communicate their findings. With this article, we want to create awareness of the work in this special area of language studies and of the inherent cross-disciplinarity that makes LSP special compared to common-core language. An acknowledgement of the importance of this field both in terms...
Lauridsen, Karen M.
Like any other text, instructive texts function within a given cultural and situational setting and may only be available in one language. However, the end users may not be familiar with that language and therefore unable to read and understand the instructions. This article therefore argues...... that instructive texts should always be available in a language that is understood by the end users, and that a corporate communication policy which includes a language policy should ensure that this is in fact the case for all instructive texts....
Human languages evolve by a process of descent with modification in which parent languages give rise to daughter languages over time and in a manner that mimics the evolution of biological species. Descent with modification is just one of many parallels between biological and linguistic evolution that, taken together, offer up a Darwinian perspective on how languages evolve. Combined with statistical methods borrowed from evolutionary biology, this Darwinian perspective has brought new opportunities to the study of the evolution of human languages. These include the statistical inference of phylogenetic trees of languages, the study of how linguistic traits evolve over thousands of years of language change, the reconstruction of ancestral or proto-languages, and using language change to date historical events.
Galdzicki, Michal; Rodriguez, Cesar; Chandran, Deepak; Sauro, Herbert M; Gennari, John H
We have created the Knowledgebase of Standard Biological Parts (SBPkb) as a publically accessible Semantic Web resource for synthetic biology (sbolstandard.org). The SBPkb allows researchers to query and retrieve standard biological parts for research and use in synthetic biology. Its initial version includes all of the information about parts stored in the Registry of Standard Biological Parts (partsregistry.org). SBPkb transforms this information so that it is computable, using our semantic framework for synthetic biology parts. This framework, known as SBOL-semantic, was built as part of the Synthetic Biology Open Language (SBOL), a project of the Synthetic Biology Data Exchange Group. SBOL-semantic represents commonly used synthetic biology entities, and its purpose is to improve the distribution and exchange of descriptions of biological parts. In this paper, we describe the data, our methods for transformation to SBPkb, and finally, we demonstrate the value of our knowledgebase with a set of sample queries. We use RDF technology and SPARQL queries to retrieve candidate "promoter" parts that are known to be both negatively and positively regulated. This method provides new web based data access to perform searches for parts that are not currently possible.
Full Text Available We have created the Knowledgebase of Standard Biological Parts (SBPkb as a publically accessible Semantic Web resource for synthetic biology (sbolstandard.org. The SBPkb allows researchers to query and retrieve standard biological parts for research and use in synthetic biology. Its initial version includes all of the information about parts stored in the Registry of Standard Biological Parts (partsregistry.org. SBPkb transforms this information so that it is computable, using our semantic framework for synthetic biology parts. This framework, known as SBOL-semantic, was built as part of the Synthetic Biology Open Language (SBOL, a project of the Synthetic Biology Data Exchange Group. SBOL-semantic represents commonly used synthetic biology entities, and its purpose is to improve the distribution and exchange of descriptions of biological parts. In this paper, we describe the data, our methods for transformation to SBPkb, and finally, we demonstrate the value of our knowledgebase with a set of sample queries. We use RDF technology and SPARQL queries to retrieve candidate "promoter" parts that are known to be both negatively and positively regulated. This method provides new web based data access to perform searches for parts that are not currently possible.
A. E. Pismak
Full Text Available Subject of Research. The paper is focused on Wiktionary articles structural organization in the aspect of its usage as the base for semantic network. Wiktionary community references, article templates and articles markup features are analyzed. The problem of numerical estimation for semantic similarity of structural elements in Wiktionary articles is considered. Analysis of existing software for semantic similarity estimation of such elements is carried out; algorithms of their functioning are studied; their advantages and disadvantages are shown. Methods. Mathematical statistics methods were used to analyze Wiktionary articles markup features. The method of semantic similarity computing based on statistics data for compared structural elements was proposed.Main Results. We have concluded that there is no possibility for direct use of Wiktionary articles as the source for semantic network. We have proposed to find hidden similarity between article elements, and for that purpose we have developed the algorithm for calculation of confidence coefficients proving that each pair of sentences is semantically near. The research of quantitative and qualitative characteristics for the developed algorithm has shown its major performance advantage over the other existing solutions in the presence of insignificantly higher error rate. Practical Relevance. The resulting algorithm may be useful in developing tools for automatic Wiktionary articles parsing. The developed method could be used in computing of semantic similarity for short text fragments in natural language in case of algorithm performance requirements are higher than its accuracy specifications.
Speech is bound to variations precisely located of the cerebral activity. The analysis is not easy: the enunciation is the most complicated motive act that we can achieve. The cerebral imagery (NMR imaging) presents an inadequate temporal and spatial resolution for following in real time a word enunciation process but gives nevertheless some good informations. A speech mapping has been outlined though as well as a sort of speech dynamics. Thus, it has been verified that saying abstract words can be explained by a higher blood flow than the enunciation of concrete words. (O.M.)
Gong, Tao; Shuai, Lan; Zhang, Menghan
We survey recent computer modelling research of language evolution, focusing on a rule-based model simulating the lexicon-syntax coevolution and an equation-based model quantifying the language competition dynamics. We discuss four predictions of these models: (a) correlation between domain-general abilities (e.g. sequential learning) and language-specific mechanisms (e.g. word order processing); (b) coevolution of language and relevant competences (e.g. joint attention); (c) effects of cultural transmission and social structure on linguistic understandability; and (d) commonalities between linguistic, biological, and physical phenomena. All these contribute significantly to our understanding of the evolutions of language structures, individual learning mechanisms, and relevant biological and socio-cultural factors. We conclude the survey by highlighting three future directions of modelling studies of language evolution: (a) adopting experimental approaches for model evaluation; (b) consolidating empirical foundations of models; and (c) multi-disciplinary collaboration among modelling, linguistics, and other relevant disciplines.
Hall, Matthew L.; Ferreira, Victor S.; Mayberry, Rachel I.
Psycholinguistic studies of sign language processing provide valuable opportunities to assess whether language phenomena, which are primarily studied in spoken language, are fundamentally shaped by peripheral biology. For example, we know that when given a choice between two syntactically permissible ways to express the same proposition, speakers tend to choose structures that were recently used, a phenomenon known as syntactic priming. Here, we report two experiments testing syntactic primin...
Combinational pixel-by-pixel and object-level classifying, segmenting, and agglomerating in performing quantitative image analysis that distinguishes between healthy non-cancerous and cancerous cell nuclei and delineates nuclear, cytoplasm, and stromal material objects from stained biological tissue materials
Boucheron, Laura E
Quantitative object and spatial arrangement-level analysis of tissue are detailed using expert (pathologist) input to guide the classification process. A two-step method is disclosed for imaging tissue, by classifying one or more biological materials, e.g. nuclei, cytoplasm, and stroma, in the tissue into one or more identified classes on a pixel-by-pixel basis, and segmenting the identified classes to agglomerate one or more sets of identified pixels into segmented regions. Typically, the one or more biological materials comprises nuclear material, cytoplasm material, and stromal material. The method further allows a user to markup the image subsequent to the classification to re-classify said materials. The markup is performed via a graphic user interface to edit designated regions in the image.
Although most children acquire language effortlessly, there are some children who find learning language a difficult and arduous task. This group of subjects resembles a natural experiment and has the potential to provide us with insights into the nature of the biological basis of language. The data show that this disorder is associated with certain genetic factors that can lead to neurological abnormalities. Our studies of the linguistic details of language impairment in English, French, Greek and Japanese have led us to conclude that affected individuals cannot construct normal representations for complex words nor can they construct the rules which should operate on these representations. These data are inconsistent with any explanation in terms of auditory or articulatory processing. Therefore, we must conclude that a genetic disorder can impair the ability to build a normal grammar.
Oller, D Kimbrough; Dale, Rick; Griebel, Ulrike
This article introduces the Special Issue and its focus on research in language evolution with emphasis on theory as well as computational and robotic modeling. A key theme is based on the growth of evolutionary developmental biology or evo-devo. The Special Issue consists of 13 articles organized in two sections: A) Theoretical foundations and B) Modeling and simulation studies. All the papers are interdisciplinary in nature, encompassing work in biological and linguistic foundations for the study of language evolution as well as a variety of computational and robotic modeling efforts shedding light on how language may be developed and may have evolved. Copyright © 2016 Cognitive Science Society, Inc.
Systems biology seeks to study biological systems as a whole, contrary to the reductionist approach that has dominated biology. Such a view of biological systems emanating from strong foundations of molecular level understanding of the individual components in terms of their form, function and interactions is promising to ...
Skelton, Alice E; Catchpole, Gemma; Abbott, Joshua T; Bosten, Jenny M; Franklin, Anna
The biological basis of the commonality in color lexicons across languages has been hotly debated for decades. Prior evidence that infants categorize color could provide support for the hypothesis that color categorization systems are not purely constructed by communication and culture. Here, we investigate the relationship between infants' categorization of color and the commonality across color lexicons, and the potential biological origin of infant color categories. We systematically mapped infants' categorical recognition memory for hue onto a stimulus array used previously to document the color lexicons of 110 nonindustrialized languages. Following familiarization to a given hue, infants' response to a novel hue indicated that their recognition memory parses the hue continuum into red, yellow, green, blue, and purple categories. Infants' categorical distinctions aligned with common distinctions in color lexicons and are organized around hues that are commonly central to lexical categories across languages. The boundaries between infants' categorical distinctions also aligned, relative to the adaptation point, with the cardinal axes that describe the early stages of color representation in retinogeniculate pathways, indicating that infant color categorization may be partly organized by biological mechanisms of color vision. The findings suggest that color categorization in language and thought is partially biologically constrained and have implications for broader debate on how biology, culture, and communication interact in human cognition.
Inquiry into the evolution of some biological system evidently can proceed only as far as its nature is understood. Lacking such understanding, its manifestations are likely to appear to be chaotic, highly variable, and lacking significant general properties; and, accordingly, study of its evolution cannot be seriously undertaken. These truisms hold of the study of the human faculty of language FL just as for other biological systems. As discussed below, FL appears to be a shared human capacity in essentials, with options of variation of a kind to which we return. After a long lapse, the problem of evolution of language arose in mid-twentieth century when the first efforts were made to construct accounts of FL as a biological object, internal to an individual, with particular internal languages - I-languages in current terminology - as manifestations of FL. Copyright © 2017. Published by Elsevier Ltd.
... Oral — Natural Gestures, Listening, Speech (Lip) Reading, Speech Auditory-Verbal — Listening, Speech Bilingual — American Sign Language, Finger Spelling, Natural Gestures Cued Speech — Cueing, Speech (Lip) Reading Total Communication — Conceptually Accurate Signed English (CASE), Finger Spelling, Listening, ...
Rijkhoff, Jan; Bakker, Dik
This article has two aims:  to present a revised version of the sampling method that was originally proposed in 1993 by Rijkhoff, Bakker, Hengeveld and Kahrel, and  to discuss a number of other approaches to language sampling in the light of our own method. We will also demonstrate how our...
Home; Journals; Resonance – Journal of Science Education; Volume 3; Issue 12. Programming Languages - A Brief Review ... IBM Professor of Information Technology, Jawaharlal Nehru Centre for Advanced Scientific Research, Bangalore 560012, India; Hon.Professor, Supercomputer Education & Research Centre ...
Original title: Taal lokaal. Children of immigrants living in the Netherlands have for years had the opportunity to receive lessons in their mother tongue at primary school. Since 1998 this has been referred to as minority language teaching (OALT in Dutch), and has been the responsibility
The Le Rosey Institute at Rolle (autumn and spring) and Gstaad (winter) is looking for part-time language teachers of Bulgarian, Farsi, Hindi, Korean and Romanian for the start of the autumn term in September 2007. For further details, please contact : www.rosey.ch Please send applications with CVs to firstname.lastname@example.org
Marygold Steven J
Full Text Available Abstract Background Journal articles and databases are two major modes of communication in the biological sciences, and thus integrating these critical resources is of urgent importance to increase the pace of discovery. Projects focused on bridging the gap between journals and databases have been on the rise over the last five years and have resulted in the development of automated tools that can recognize entities within a document and link those entities to a relevant database. Unfortunately, automated tools cannot resolve ambiguities that arise from one term being used to signify entities that are quite distinct from one another. Instead, resolving these ambiguities requires some manual oversight. Finding the right balance between the speed and portability of automation and the accuracy and flexibility of manual effort is a crucial goal to making text markup a successful venture. Results We have established a journal article mark-up pipeline that links GENETICS journal articles and the model organism database (MOD WormBase. This pipeline uses a lexicon built with entities from the database as a first step. The entity markup pipeline results in links from over nine classes of objects including genes, proteins, alleles, phenotypes and anatomical terms. New entities and ambiguities are discovered and resolved by a database curator through a manual quality control (QC step, along with help from authors via a web form that is provided to them by the journal. New entities discovered through this pipeline are immediately sent to an appropriate curator at the database. Ambiguous entities that do not automatically resolve to one link are resolved by hand ensuring an accurate link. This pipeline has been extended to other databases, namely Saccharomyces Genome Database (SGD and FlyBase, and has been implemented in marking up a paper with links to multiple databases. Conclusions Our semi-automated pipeline hyperlinks articles published in GENETICS to
The paper examines the pros and cons of the checkered nature of language use in the Tanzanian Parliament. It focuses on language policy, language choice and the practicality of language use in parliamentary discourse. Right from the eve of independence, the medium of communication in the Tanzanian parliament has ...
American Speech-Language-Hearing Association. Preschool language disorders. www.asha.org/public/speech/disorders/Preschool-Language-Disorders . Accessed July 8, 2016. Nass R, Trauner DA. Developmental language disorders. ...
The author reflects on foreign-language learning by his EFL students as well as his own foreign-language learning. He concludes by musing on the possible and fantastical devastation on language-ability wrought by strokes.
Skelton, Alice E.; Catchpole, Gemma; Abbott, Joshua T.; Bosten, Jenny M.; Franklin, Anna
The biological basis of the commonality in color lexicons across languages has been hotly debated for decades. Prior evidence that infants categorize color could provide support for the hypothesis that color categorization systems are not purely constructed by communication and culture. Here, we investigate the relationship between infants’ categorization of color and the commonality across color lexicons, and the potential biological origin of infant color categories. We systematically mappe...
Taljard , Elsabé
In 2006, the South African Department of Education initiated a pilot project in which the Matric or Senior Certificate papers for Science, Maths, Biology and History were translated into the nine official African/Bantu languages of the country. Grade 12 learners who use these languages as home languages therefore received a question paper containing questions in English, where every question was followed by its translation into the relevant language. Taking into consideration that these learn...
Spatial language constitutes part of the basic fabric of language. Although languages may have the same number of terms to cover a set of spatial relations, they do not always do so in the same way. Spatial languages differ across languages quite radically, thus providing a real semantic challenge for second language learners. The essay first…
Introduction and Biological BackgroundBiological ComputationThe Influence of Biology on Mathematics-Historical ExamplesBiological IntroductionModels and Simulations Cellular Automata Biological BackgroundThe Game of Life General Definition of Cellular Automata One-Dimensional AutomataExamples of Cellular AutomataComparison with a Continuous Mathematical Model Computational UniversalitySelf-Replication Pseudo Code Evolutionary ComputationEvolutionary Biology and Evolutionary ComputationGenetic AlgorithmsExample ApplicationsAnalysis of the Behavior of Genetic AlgorithmsLamarckian Evolution Genet
Cox, Robert Sidney
As protein engineering becomes more sophisticated, practitioners increasingly need to share diagrams for communicating protein designs. To this end, we present a draft visual language, Protein Language, that describes the high-level architecture of an engineered protein with easy-to draw glyphs, intended to be compatible with other biological diagram languages such as SBOL Visual and SBGN. Protein Language consists of glyphs for representing important features (e.g., globular domains, recognition and localization sequences, sites of covalent modification, cleavage and catalysis), rules for composing these glyphs to represent complex architectures, and rules constraining the scaling and styling of diagrams. To support Protein Language we have implemented an extensible web-based software diagram tool, Protein Designer, that uses Protein Language in a
Gary F. Simons
Full Text Available Language documentation faces challenges of data preservation and accessibility. Data can be lost due to physical deterioration (e.g. field notes or tape recordings or outdated format (e.g. Microsoft Word 3.0. Archived data is typically difficult to access, and it is sometimes found that the archived information is inadequate for research purposes. Increased interest in language documentation has coincided with advancements in digital technologies, offering hope for meeting these challenges. This paper discusses the archiving of a 204-item wordlist of Ngbugu, an Ubangian language spoken in Central African Republic, employing best practice recommendations. Our solution includes: TIFF digital imaging of the original handwritten transcription, WAV digital recording of the wordlist, descriptive markup encoding of the wordlist in XML employing Unicode transcription, viewing and playback via an XSLT style sheet that renders the information in HTML, publishing metadata for resource discovery with the Open Language Archives Community (OLAC, and depositing the original materials and digital representations in an institutional archive committed to long-term preservation and access.
Liddicoat, Anthony, Ed.
A five-year period of particular activity in Australian language policy and language planning culminated with the 1991 publication of the White Paper called Australia's Language, which outlines proposed government programs in languages until 1994. Many of the papers in this theme issue of the journal of the Applied Linguistics Association of…
Prochazkova, Lenka Tejkalova
The author discusses the balance and mutual influence of the language of instruction and mathematics in the context of CLIL, Content and Language Integrated Learning. Different aspects of the relationship of language and Mathematics teaching and learning are discussed: the benefits of using a foreign language of instruction, as well as the…
The results for that intervention show that the hypothesis was correct and students need more time and structure if they are to improve their language competence sufficiently. Keywords: language learning interventions, English for specific purposes, language competence, fossilization. Journal for Language Teaching Vol.
Full Text Available Natural and intuitive interaction between users and complex systems is a crucial research topic in human-computer interaction. A major direction is the definition and implementation of systems with natural language understanding capabilities. The interaction in natural language is often performed by means of systems called chatbots. A chatbot is a conversational agent with a proper knowledge base able to interact with users. Chatbots appearance can be very sophisticated with 3D avatars and speech processing modules. However the interaction between the system and the user is only performed through textual areas for inputs and replies. An interaction able to add to natural language also graphical widgets could be more effective. On the other side, a graphical interaction involving also the natural language can increase the comfort of the user instead of using only graphical widgets. In many applications multi-modal communication must be preferred when the user and the system have a tight and complex interaction. Typical examples are cultural heritages applications (intelligent museum guides, picture browsing or systems providing the user with integrated information taken from different and heterogenous sources as in the case of the iGoogle™ interface. We propose to mix the two modalities (verbal and graphical to build systems with a reconfigurable interface, which is able to change with respect to the particular application context. The result of this proposal is the Graphical Artificial Intelligence Markup Language (GAIML an extension of AIML allowing merging both interaction modalities. In this context a suitable chatbot system called Graphbot is presented to support this language. With this language is possible to define personalized interface patterns that are the most suitable ones in relation to the data types exchanged between the user and the system according to the context of the dialogue.
This review begins with a definition of biological evolution and a description of its general principles. This is followed by a presentation of the biological basis of culture, specifically the concept of social selection. Further, conditions for cultural evolution are proposed, including a suggestion for language being the cultural ...
Abstract. This review begins with a definition of biological evolution and a description of its general principles. This is followed by a presentation of the biological basis of culture, specifically the concept of social selection. Further, conditions for cultural evolution are proposed, including a suggestion for language being the ...
PermanenceA "permanence" for language Training has been set up. If anyone has a question or requires information on any aspect of English or French training please come to our office 5 4-016 at the following times. Lucette Fournier French courses Monday 13.30 - 15.30 Tuesday\t10.30 - 12.30 Tessa Osborne English courses Wednesday\t12.00 - 14.00 Thursday\t11.00 - 13.00 New courses Specific English and French courses - Exam preparation/ We are now offering specific courses in English and French leading to a recognised external examination (e.g. Cambridge, DELF and BULATS). If you are interested in following one of these courses and have at least an upper intermediate level of English or French, please enrol through the following link: http://English courses http://French courses Or contact: Tessa Osborne 72957 (English courses) Lucette Fournier 73483 (French courses) Language Training Nathalie Dumeaux Tel. 78144 mailto:email@example.com
Permanence A "permanence" for language Training has been set up. If anyone has a question or requires information on any aspect of English or French training please come to our office 5 4-016 at the following times. Lucette Fournier - French courses Monday 13.30 - 15.30 Tuesday\t10.30 - 12.30 Tessa Osborne - English courses Wednesday\t12.00 - 14.00 Thursday\t11.00 - 13.00 New courses Specific English and French courses - Exam preparation/ We are now offering specific courses in English and French leading to a recognised external examination (e.g. Cambridge, DELF, DALF). If you are interested in following one of these courses and have at least an upper intermediate level of English or French, please enrol through the following link: English courses French courses Or contact: Tessa Osborne 72957 (English courses) Lucette Fournier 73483 (French courses) Language Training Nathalie Dumeaux Tel. 78144 firstname.lastname@example.org
If you wish to participate in one of the following courses, please discuss with your supervisor and apply electronically directly from the course description pages that can be found on the Web at: http://www.cern.ch/Training/ or fill in an "application for training" form available from your Divisional Secretariat or from your DTO (Divisional Training Officer). Applications will be accepted in the order of their receipt. LANGUAGE TRAINING Françoise Benz tel. 73127 email@example.com FRENCH TRAINING General and Professional French Courses The next session will take place from 26 January to 02 April 2004. These courses are open to all persons working on the Cern site, and to their spouses. For registration and further information on the courses, please consult our Web pages: http://cern.ch/Training or contact Mrs. Benz: Tel. 73127. Writing Professional Documents in French The next session will take place from 26 January to 02 April 2004. This course is designed for people wi...
If you wish to participate in one of the following courses, please discuss with your supervisor and apply electronically directly from the course description pages that can be found on the Web at: http://www.cern.ch/Training/ or fill in an "application for training" form available from your Divisional Secretariat or from your DTO (Divisional Training Officer). Applications will be accepted in the order of their receipt. LANGUAGE TRAINING Françoise Benz tel. 73127 firstname.lastname@example.org FRENCH TRAINING General and Professional French Courses The next session will take place from 26 January to 02 April 2004. These courses are open to all persons working on the Cern site, and to their spouses. For registration and further information on the courses, please consult our Web pages: http://cern.ch/Training or contact Mrs. Benz : Tel. 73127. Writing Professional Documents in French The next session will take place from 26 January to 02 April 2004. This course is designed for peop...
If one of your New Year’s resolutions is to learn a language, there is no excuse any more. You can attend one of our English or French courses and you can practise the language with a tandem partner! General & Professional French courses The next General & Professional French course will start on 26 January. These collective courses aim to bring participants who have at least level A1 to higher levels (up to C2). Each level consists of a combination of face-to-face sessions (40 hours) with personal work (20 hours) following a specially designed programme. A final progress test takes place at the end of the term. Please note that it is mandatory to take the placement test. Please sign up here. French courses for beginners The aim of this course is to give some basic skills to beginners in order to communicate in simple everyday situations in both social and professional life. These courses can start at any time during the year, as soon as a group of beg...
Richards, Heather; Conway, Clare; Roskvist, Annelies; Harvey, Sharon
Teachers' subject knowledge is recognized as an essential component of effective teaching. In the foreign language context, teachers' subject knowledge includes language proficiency. In New Zealand high schools, foreign languages (e.g. Chinese, French, German, Japanese and Spanish) have recently been offered to learners earlier in their schooling,…
Chun, Dorothy; Smith, Bryan; Kern, Richard
This article offers a capacious view of technology to suggest broad principles relating technology and language use, language teaching, and language learning. The first part of the article considers some of the ways that technological media influence contexts and forms of expression and communication. In the second part, a set of heuristic…
Haberland, Hartmut; Mortensen, Janus
Introduction to thematic issue on Language variety, language hierarchy, and language choice in the international university......Introduction to thematic issue on Language variety, language hierarchy, and language choice in the international university...
Kumar, Rajesh; Yunus, Reva
This article looks at the contribution of insights from theoretical linguistics to an understanding of language acquisition and the nature of language in terms of their potential benefit to language education. We examine the ideas of innateness and universal language faculty, as well as multilingualism and the language-society relationship. Modern…
Korenev, Alexey; Westbrook, Carolyn; Merry, Yvonne; Ershova, Tatiana
The Language Teachers' Target Language project (LTTL) aims to describe language teachers' target language use domain (Bachman & Palmer 2010) and to develop a language test for future teachers of English. The team comprises four researchers from Moscow State University (MSU) and Southampton Solent University.
Languages with a solvable implication problem but without complete and consistent systems of inference rules (`poor` languages) are considered. The problem of existence of finite complete and consistent inference rule system for a ``poor`` language is stated independently of the language or rules syntax. Several properties of the problem arc proved. An application of results to the language of join dependencies is given.
Examines the resilience of small languages in the face of larger ones. Highlights include the concept of one dominant language, such as Esperanto; the threat of television to small visual-language societies; the power of visual media; man's relationship to language; and the resilience of language. (LRW)
Oostdam, R.; Rijlaarsdam, Gert
Towards Strategic Language Learning is the result of extensive research in the relationship between mother tongue education and foreign language learning. As language skills that are taught during native language lessons are applied in foreign language performance as well, it is vital that curricula
Park, Joseph Sung-Yul
Language occupies a crucial position in neoliberalism, due to the reimagination of language as commodified skill. This paper studies the role of language ideology in this transformation by identifying a particular ideology that facilitates this process, namely the ideology which views language as pure potential. Neoliberalism treats language as a…
It is well known that humans are creating new variants of organisms, ecosystems and landscapes. Here I argue that the degree of biological novelty generated by humans goes deeper than that. We use property rules to create exclusivity in cooperation among humans, and between humans and other biological entities, thus overcoming social dilemmas and breaking barriers to cooperation. This is leading to novel forms of cooperation. One of them is the human control, modification and replication of whole ecosystems. For the first time, there exist ecosystems with functional design, division of labor and unlimited heredity. We use mental representation and language as new mechanisms of inheritance and modification that apply to an increasing variety of biological and non-biological entities. As a result, the speed, depth and scale of biological innovation are unprecedented in the history of life. Copyright © 2017 Elsevier Ltd. All rights reserved.
Wiley, H S.
The biology revolution over the last 50 years has been driven by the ascendancy of molecular biology. This was enthusiastically embraced by most biologists because it took us into increasingly familiar territory. It took mysterious processes, such as the replication of genetic material and assigned them parts that could be readily understood by the human mind. When we think of ''molecular machines'' as being the underlying basis of life, we are using a paradigm derived from everyday experience. However, the price that we paid was a relentless drive towards reductionism and the attendant balkanization of biology. Now along comes ''systems biology'' that promises us a solution to the problem of ''knowing more and more about less and less''. Unlike molecular biology, systems biology appears to be taking us into unfamiliar intellectual territory, such as statistics, mathematics and computer modeling. Not surprisingly, systems biology has met with widespread skepticism and resistance. Why do we need systems biology anyway and how does this new area of research promise to change the face of biology in the next couple of decades?
Greenstein, Ben; Brook, Daniel A
This introductory textbook covers all the main categories of biological medicines, including vaccines, hormonal preparations, drugs for rheumatoid arthritis and other connective tissue diseases, drugs...
... Are Here: Home → Multiple Languages → All Health Topics → Domestic Violence URL of this page: https://medlineplus.gov/languages/ ... V W XYZ List of All Topics All Domestic Violence - Multiple Languages To use the sharing features on ...
... Here: Home → Multiple Languages → All Health Topics → Health Literacy URL of this page: https://medlineplus.gov/languages/ ... W XYZ List of All Topics All Health Literacy - Multiple Languages To use the sharing features on ...
... Are Here: Home → Multiple Languages → All Health Topics → Postpartum Depression URL of this page: https://medlineplus.gov/languages/ ... V W XYZ List of All Topics All Postpartum Depression - Multiple Languages To use the sharing features on ...
... Are Here: Home → Multiple Languages → All Health Topics → Zika Virus URL of this page: https://medlineplus.gov/languages/ ... V W XYZ List of All Topics All Zika Virus - Multiple Languages To use the sharing features on ...
... Are Here: Home → Multiple Languages → All Health Topics → Cesarean Section URL of this page: https://medlineplus.gov/languages/ ... V W XYZ List of All Topics All Cesarean Section - Multiple Languages To use the sharing features on ...
... Are Here: Home → Multiple Languages → All Health Topics → Child Abuse URL of this page: https://medlineplus.gov/languages/ ... V W XYZ List of All Topics All Child Abuse - Multiple Languages To use the sharing features on ...
... Are Here: Home → Multiple Languages → All Health Topics → Panic Disorder URL of this page: https://medlineplus.gov/languages/ ... V W XYZ List of All Topics All Panic Disorder - Multiple Languages To use the sharing features on ...
... Are Here: Home → Multiple Languages → All Health Topics → Herbal Medicine URL of this page: https://medlineplus.gov/languages/ ... V W XYZ List of All Topics All Herbal Medicine - Multiple Languages To use the sharing features on ...
... Here: Home → Multiple Languages → All Health Topics → Cosmetic Dentistry URL of this page: https://medlineplus.gov/languages/ ... W XYZ List of All Topics All Cosmetic Dentistry - Multiple Languages To use the sharing features on ...
... Are Here: Home → Multiple Languages → All Health Topics → Oral Cancer URL of this page: https://medlineplus.gov/languages/ ... V W XYZ List of All Topics All Oral Cancer - Multiple Languages To use the sharing features on ...
Révész, György E
Covers all areas, including operations on languages, context-sensitive languages, automata, decidability, syntax analysis, derivation languages, and more. Numerous worked examples, problem exercises, and elegant mathematical proofs. 1983 edition.
Damgaard, Troels Christoffer
to include application of structural congruence. We isolate a class of normal inferences, and prove that normal inferences are sufficient for inferring all matches. The matching algorithm relies on building normal inferences mechanically. An implementation of the algorithm is at the core of the BPL Tool...... side-conditions. As an example, we show that the nondeterministic -calculus (due to Danos and Laneve) can be modelled. Finally, we build on our study above and develop a formal language, the C-calculus, for modelling low-level interaction inside and among cells. At the core of the calculus lies a model...... of formal proteins and membranes. In addition, formal channels between compartments allow us to model an intermediate state in cell fusion or division, regulated by diffusion. A user models in the C-calculus by refining a set of core rules, each of which encapsulates a core biological reaction. We...
Arbib's computational comparative neuroprimatology  is a welcome model for cognitive linguists, that is, linguists who ground their models of language in human cognition and language use in social interaction. Arbib argues that language emerged via biological and cultural coevolution ; linguistic knowledge is represented by constructions, and semantic representations of linguistic constructions are grounded in embodied perceptual-motor schemas (the mirror system hypothesis). My comments offer some refinements from a linguistic point of view.
A widespread and influential characterization of synthetic biology emphasizes that synthetic biology is the application of engineering principles to living systems. Furthermore, there is a strong tendency to express the engineering approach to organisms in terms of what seems to be an ontological claim: organisms are machines. In the paper I investigate the ontological and heuristic significance of the machine analogy in synthetic biology. I argue that the use of the machine analogy and the aim of producing rationally designed organisms does not necessarily imply a commitment to mechanical biology. The ideal of applying engineering principles to biology is best understood as expressing recognition of the machine-unlikeness of natural organisms and the limits of human cognition. The paper suggests an interpretation of the identification of organisms with machines in synthetic biology according to which it expresses a strategy for representing, understanding, and constructing living systems that are more machine-like than natural organisms.
Natural language processing (NLP) work began more than sixty years ago; it is a field of computer science and linguistics devoted to creating computer systems that use human (natural) language. Natural Language Processing holds great promise for making computer interfaces that are easier to use for people, since people will be able to talk to the computer in their own language, rather than learn a specialized language of computer commands. Natural Language processing techniques can make possi...
-ecology. While shaped by discourse and beliefs about language-systems (and representations), the language and actions of human organism–environment systems change the world. As Garner (2004) argues, ecolinguistics can do more than invoke ‘interaction’ between language and ecology. While ‘realities’ are partly......The paper asks how languaging and language influence the world of the living. Extending Clements and Shelford (1939), the bio-ecology is redefined as the domain of plant–animal–human–culture formations. The move places what people do as a result of languaging into a reciprocal relation with the bio...... shared, much is biophysical. Living subjects link language and languaging with experience and technologies that have transformed the bio-ecology. Once these dynamics are subject to investigation, macrosocial issues can be reconnected with biological, human and linguistic concerns. Ecolinguistics can thus...
Abstract. In this paper we present a qualitative outlook of mesoscopic biology where the typical length scale is of the order of nanometers and the energy scales comparable to thermal energy. ... National Center for Biological Sciences, Tata Institute of Fundamental Research, UAS-GKVK Campus, Bangalore 560 065, India ...
Hartmann, Lars Røeboe; Jones, Neil; Simonsen, Jakob Grue
Computation via biological devices has been the subject of close scrutiny since von Neumann’s early work some 60 years ago. In spite of the many relevant works in this field, the notion of programming biological devices seems to be, at best, ill-defined. While many devices are claimed or proved t...
In this paper we present a qualitative outlook of mesoscopic biology where the typical length scale is of the order of nanometers and the energy scales comparable to thermal energy. Novel biomolecular machines, governed by coded information at the level of DNA and proteins, operate at these length scales in biological ...
This paper provides a panoramic description of the ways in which the so-called Critical Language Awareness (CLA), can contribute to the teaching and learning of English as a global language, which increasingly involves a wide range of visual, verbal, and digitally-delivered media and modes of communication. The overview presented begins with the concept of Language Awareness, and goes into more depth with respect to that of Critical Language Awareness, establishing a parallel with Paulo Freir...
Recently, the applied linguistics field has examined the knowledge, skills, and principles needed for assessment, defined as language assessment literacy. Two major issues in language assessment literacy have been addressed but not fully resolved--what exactly language assessment literacy is and how it differs among stakeholders (e.g., students…
Baxter, William H., III
Singapore's language policy must balance the wishes of the various ethnic groups, the political situation in the regions, and the needs of economic development. Malay, Mandarin Chinese, English, and Tamil are all recognized as official languages. Malay has special symbolic status as the national language. (RM)
Full Text Available A critical assessment of the recent developmentsof molecular biology is presented.The thesis that they do not lead to a conceptualunderstanding of life and biological systems is defended.Maturana and Varela's concept of autopoiesis is briefly sketchedand its logical circularity avoided by postulatingthe existence of underlying living processes,entailing amplification from the microscopic to the macroscopic scale,with increasing complexity in the passage from one scale to the other.Following such a line of thought, the currently accepted model of condensed matter, which is based on electrostatics and short-ranged forces,is criticized. It is suggested that the correct interpretationof quantum dispersion forces (van der Waals, hydrogen bonding, and so onas quantum coherence effects hints at the necessity of includinglong-ranged forces (or mechanisms for them incondensed matter theories of biological processes.Some quantum effects in biology are reviewedand quantum mechanics is acknowledged as conceptually important to biology since withoutit most (if not all of the biological structuresand signalling processes would not even exist. Moreover, it is suggested that long-rangequantum coherent dynamics, including electron polarization,may be invoked to explain signal amplificationprocess in biological systems in general.
The ocean is arguably the largest habitat on the planet, and it houses an astounding array of life, from microbes to whales. As a testament to this diversity and its importance, the discipline of biological oceanography spans studies of all levels of biological organization, from that of single genes, to organisms, to their population dynamics. Biological oceanography also includes studies on how organisms interact with, and contribute to, essential global processes. Students of biological oceanography are often as comfortable looking at satellite images as they are electron micrographs. This diversity of perspective begins the textbook Biological Oceanography, with cover graphics including a Coastal Zone Color Scanner image representing chlorophyll concentration, an electron micrograph of a dinoflagellate, and a photograph of a copepod. These images instantly capture the reader's attention and illustrate some of the different scales on which budding oceanographers are required to think. Having taught a core graduate course in biological oceanography for many years, Charlie Miller has used his lecture notes as the genesis for this book. The text covers the subject of biological oceanography in a manner that is targeted to introductory graduate students, but it would also be appropriate for advanced undergraduates.
Full Text Available In this paper we describe a preliminary, work-in-progress Spoken Language Understanding Software (SLUS with tailored feedback options, which uses interactive spoken language interface to teach Iraqi Arabic and culture to second language learners. The SLUS analyzes input speech by the second language learner and grades for correct pronunciation in terms of supra-segmental and rudimentary segmental errors such as missing consonants. We evaluated this software on training data with the help of two native speakers, and found that the software recorded an accuracy of around 70% in law and order domain. For future work, we plan to develop similar systems for multiple languages.
Michael A. Arbib's Mirror System Hypothesis (MSH) [1,2] is among the most elaborate attempts at disentangling the issue of language origin. I will focus on the role that cultural evolution, as distinct from biological (genetic) evolution, may have played in the emergence of ;modern; human language (as contrasted with forms of proto-languages).
Full Text Available Recently, the applied linguistics field has examined the knowledge, skills, and principles needed for assessment, defined as language assessment literacy. Two major issues in language assessment literacy have been addressed but not fully resolved—what exactly language assessment literacy is and how it differs among stakeholders (e.g., students and teachers. This reflective article reviews assessment literacy from general education experts and language education scholars and shows how the meaning of language assessment literacy has expanded. To add to the discussion of this construct, the article focuses on the specific language assessment literacy for language teachers and proposes a core list of assessment knowledge, skills, and principles for these stakeholders.
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Language and thinking give us access to what is usually called natural and social reality. Language and thinking can be considered as parts of a semiotic universe of different entities from which emerge different subsets. Some of these can have peculiar functions in interpersonal interactions and biological transductions. Nonlinear studies at the morphological level of language are opening new perpectives in this area of the Mind-Sciences.
Appel, René; Muysken, Pieter
What happens - sociologically, linguistically, educationally, politically - when more than one language is in regular use in a community? How do speakers handle these languages simultaneously, and what influence does this language contact have on the languages involved? Although most people in the
A range of views on mixed languages and their connections to phenomena such as secret languages, massive borrowing, codeswitching and codemixing, and thier origin.......A range of views on mixed languages and their connections to phenomena such as secret languages, massive borrowing, codeswitching and codemixing, and thier origin....
Richards, Jack C.
One quality among the many that characterize effective teachers is the ability to bring a creative disposition to teaching. In second language teaching, creativity has also been linked to levels of attainment in language learning. Many of the language tasks favored by contemporary language teaching methods are believed to release creativity in…
Abat Ninet, Antoni
existing languages in a new born state. The discussion began remarking upon the enormous significance of language in political, identity and constitutional terms. It follows comparing different constitutional systems in the world and the status of minority languages in Argentina, Bolivia, Croatia, Serbia....... The paper emphasises the international human right to language, and proposes an accommodation strategy in which the traditional majority language forms the lingua franca, other major languages are granted equal official status, and the government promotes and respects important minority languages. The paper...
Lee, S; Hasegawa, T
Good barriers make good languages. Scholars have long speculated that geographical barriers impede linguistic contact between speech communities and promote language diversification in a manner similar to the process of allopatric speciation. This hypothesis, however, has seldom been tested systematically and quantitatively. Here, we adopt methods from evolutionary biology and attempt to quantify the influence of oceanic barriers on the degree of lexical diversity in the Japanese Islands. Measuring the degree of beta diversity from basic vocabularies, we find that geographical proximity and, more importantly, isolation by surrounding ocean, independently explains a significant proportion of lexical variation across Japonic languages. Further analyses indicate that our results are neither a by-product of using a distance matrix derived from a Bayesian language phylogeny nor an epiphenomenon of accelerated evolutionary rates in languages spoken by small communities. Moreover, we find that the effect of oceanic barriers is reproducible with the Ainu languages, indicating that our analytic approach as well as the results can be generalized beyond Japonic language family. The findings we report here are the first quantitative evidence that physical barriers formed by ocean can influence language diversification and points to an intriguing common mechanism between linguistic and biological evolution. © 2014 The Authors. Journal of Evolutionary Biology published by John Wiley & Sons Ltd on behalf of European Society for Evolutionary Biology.
In addition to providing an account of the empirical facts of language, a theory that aspires to account for language as a biologically based human faculty should seek a graceful integration of linguistic phenomena with what is known about other human cognitive capacities and about the character of brain computation. The present discussion note…
Doidge, Megan; Lelliott, Anthony
The choice of which language strategies to use in schools in Africa is the subject of much debate. In the Life Sciences, cultural issues associated with the use of biological terminology add to this debate. In our study, we examined the language choices made by Grade 7 Natural Sciences teachers in South Africa during their teaching of human…
Full Text Available This paper explores the ways in which the transfer of assumptions from first language (L1 writing can help the process of writing in second language (L2. In learning second language writing skills, learners have two primary sources from which they construct a second language system: knowledge and skills from first language and input from second language. To investigate the relative impact of first language literacy skills on second language writing ability, 60 EFL students from Tabriz Islamic Azad University were chosen as participants of this study, based on their language proficiency scores. The subjects were given two topics to write about: the experimental group subjects were asked to write in Persian and then translate their writing into English. The control group wrote in English. The results obtained in this study indicate that the content and vocabulary components of the compositions were mostly affected by the use of first language.
Karvounis, E C; Tsakanikas, V D; Fotiou, E; Fotiadis, D I
The paper proposes a novel Extensible Markup Language (XML) based format called ART-ML that aims at supporting the interoperability and the reuse of models of blood flow, mass transport and plaque formation, exported by ARTool. ARTool is a platform for the automatic processing of various image modalities of coronary and carotid arteries. The images and their content are fused to develop morphological models of the arteries in easy to handle 3D representations. The platform incorporates efficient algorithms which are able to perform blood flow simulation. In addition atherosclerotic plaque development is estimated taking into account morphological, flow and genetic factors. ART-ML provides a XML format that enables the representation and management of embedded models within the ARTool platform and the storage and interchange of well-defined information. This approach influences in the model creation, model exchange, model reuse and result evaluation.
Murphy, Caroline; Hermann, Charlotte; Andersen, Signe Hvalsøe; Grigalauskyte, Simona; Tolsgaard, Mads; Holmegaard, Thorbjørn; Hajaya, Zaedo Musa
This study examines the concept of second language learning in Denmark with focus on how second language learners negotiate their identities in relation to language learning and integration. By investigating three language learners’ acquisition of Danish through key theories on the field of second language learning, focus is centred on the subjects’ lived experiences of the learning process within their everyday lives and in the classroom. Through interviews and observations it can be conclud...
Nellemann, Kristian Lindhardt; Birk, Nikoline Aarup; Toft-Nielsen, Nina Kristine; Justice, Alexandra Isabella; Løkkegaard, Jakob Ludvig; Mørch, Cecilia
This project seeks to investigate the intricate processes immigrants in Denmark go through when learning Danish as a foreign or second language. It builds from an understanding of language as a social practice and a view of language learning as having more than a cognitive level. By combining theory on second language acquisition with theory on identity and communities of practice, this project looks to explore how immigrants through investment in language learning create or maintain a meanin...
Language learning and teaching of endangered languages have many features and needs that are quite different from the teaching of world languages. Groups whose languages are endangered try to turn language loss around; many new language teaching and learning strategies are emerging, to suit the special needs and goals of language revitalization.…
Pedersen, Michael; Phillips, Andrew
Synthetic biology aims at producing novel biological systems to carry out some desired and well-defined functions. An ultimate dream is to design these systems at a high level of abstraction using engineering-based tools and programming languages, press a button, and have the design translated to DNA sequences that can be synthesized and put to work in living cells. We introduce such a programming language, which allows logical interactions between potentially undetermined proteins and genes to be expressed in a modular manner. Programs can be translated by a compiler into sequences of standard biological parts, a process that relies on logic programming and prototype databases that contain known biological parts and protein interactions. Programs can also be translated to reactions, allowing simulations to be carried out. While current limitations on available data prevent full use of the language in practical applications, the language can be used to develop formal models of synthetic systems, which are otherwise often presented by informal notations. The language can also serve as a concrete proposal on which future language designs can be discussed, and can help to guide the emerging standard of biological parts which so far has focused on biological, rather than logical, properties of parts.
Anderson, Stephen R.; Lightfoot, David W.
This book treats human language as the manifestation of a faculty of the mind, a mental organ whose nature is determined by human biology, suggesting that its functional properties should be explored just as physiology explores the functional properties of physical organs. The book asserts that linguistics investigates cognition, taking as its…
Full Text Available Seen from the perspective of a biologist, the issue of the origin of language contains an inherent ambiguity. On the one hand, one might think to explore the cognitive features or even the anatomical structures related to communication through the peculiar medium called verbal language, a characteristic property emergent among the Homo sapiens. On the other hand, if one decides to restrict oneself to the formal definition of language as a system of signs for encoding information, then, the human-specific nature of language becomes less convincing and the temptation to look into non-human languages allows a provocative question. Was human verbal language an invention or a discovery? In the following two biologists informally discuss about the concept of non-verbal biological languages.
on offering programs rather in English than the local language. At Copenhagen Business School, 56.4% of the students at MA level followed courses in English in 2009. Many students come to Denmark from abroad, follow the English language programs offered, but are motivated to learn Danish, the local language......International (or more properly, according to Hannerz (1996), transnational) communication can happen in many languages. Focus has recently been mostly on English as the ‘lingua franca of the world’, but maybe unduly so; since there are alternatives. Especially when it comes to transnational...... student mobility, the local language of the host university can become the language of internationalization. As a starting point, I distinguish with Beck (2000) between globalization as a historical process and its result, viz. the ever changing degree of globality in world society, and from the ideology...
Manginell, Ronald P [Albuquerque, NM; Bunker, Bruce C [Albuquerque, NM; Huber, Dale L [Albuquerque, NM
A biological preconcentrator comprises a stimulus-responsive active film on a stimulus-producing microfabricated platform. The active film can comprise a thermally switchable polymer film that can be used to selectively absorb and desorb proteins from a protein mixture. The biological microfabricated platform can comprise a thin membrane suspended on a substrate with an integral resistive heater and/or thermoelectric cooler for thermal switching of the active polymer film disposed on the membrane. The active polymer film can comprise hydrogel-like polymers, such as poly(ethylene oxide) or poly(n-isopropylacrylamide), that are tethered to the membrane. The biological preconcentrator can be fabricated with semiconductor materials and technologies.
Jacques Melitz; Farid Toubal
We construct new series for common native language and common spoken language for 195 countries, which we use together with series for common official language and linguis-tic proximity in order to draw inferences about (1) the aggregate impact of all linguistic factors on bilateral trade, (2) whether the linguistic influences come from ethnicity and trust or ease of communication, and (3) in so far they come from ease of communication, to what extent trans-lation and interpreters play a role...
An overview is given of basic features of biological rhythms. The classification of periodic behavior of physical and psychological characteristics as circadian, circannual, diurnal, and ultradian is discussed, and the notion of relativistic time as it applies in biology is examined. Special attention is given to circadian rhythms which are dependent on the adrenocortical cycle. The need for adequate understanding of circadian variations in the basic physiological indicators of an individual (heart rate, body temperature, systolic and diastolic blood pressure, etc.) to ensure the effectiveness of prophylactic and therapeutic measures is stressed.
language and power issues. Drawn from all parts of the world, the contributors are active in a range of scientific and professional areas including bilingual education; sociolinguistics; the sociology of education, law and language; economics and language; linguistics; sign language; racism; communication......; discourse analysis; language policy; minority issues; and language pedagogy. The book situates issues of minorities and bilingual education in broader perspectives of human rights, power and the ecology of language. It aims at a distillation of themes that are central to an understanding of language rights...... topics can cross-fertilize each other, and that our understanding of the issues can benefit from coverage that is global, reflective and committed. A website with additional resource material to this book can be found at http://babel.ruc.dk/-robert/. Brings together scholarship in language, education...
Deriziotis, Pelagia; Fisher, Simon E
Investigation of the biological basis of human speech and language is being transformed by developments in molecular technologies, including high-throughput genotyping and next-generation sequencing of whole genomes. These advances are shedding new light on the genetic architecture underlying language-related disorders (speech apraxia, specific language impairment, developmental dyslexia) as well as that contributing to variation in relevant skills in the general population. We discuss how state-of-the-art methods are uncovering a range of genetic mechanisms, from rare mutations of large effect to common polymorphisms that increase risk in a subtle way, while converging on neurogenetic pathways that are shared between distinct disorders. We consider the future of the field, highlighting the unusual challenges and opportunities associated with studying genomics of language-related traits. Copyright © 2017 Elsevier Ltd. All rights reserved.
Full Text Available The goal of this project in Estonia was to determine what languages are spoken by students from the 2nd to the 5th year of basic school at their homes in Tallinn, the capital of Estonia. At the same time, this problem was also studied in other segregated regions of Estonia: Kohtla-Järve and Maardu. According to the database of the population census from the year 2000 (Estonian Statistics Executive Office's census 2000, there are representatives of 142 ethnic groups living in Estonia, speaking a total of 109 native languages. At the same time, the database doesn’t state which languages are spoken at homes. The material presented in this article belongs to the research topic “Home Language of Basic School Students in Tallinn” from years 2007–2008, specifically financed and ordered by the Estonian Ministry of Education and Research (grant No. ETF 7065 in the framework of an international study called “Multilingual Project”. It was determined what language is dominating in everyday use, what are the factors for choosing the language for communication, what are the preferred languages and language skills. This study reflects the actual trends of the language situation in these cities.
Vásquez, Anete; Smith, Philip C
This thoroughly revised and updated edition of Teaching Language Arts to English Language Learners provides readers with the comprehensive understanding of both the challenges that face ELLs and ways in which educators might address them in the language arts classroom. The authors offer proven techniques that teachers can readily use to teach reading, writing, grammar, and vocabulary as well as speaking, listening, and viewing skills. A complete section is also devoted to ways teachers can integrate all five strands of the language arts curriculum into a comprehensive unit of study w
Lewis, John D.
Describes XML (extensible markup language), a new language classification submitted to the World Wide Web Consortium that is defined in terms of both SGML (Standard Generalized Markup Language) and HTML (Hypertext Markup Language), specifically designed for the Internet. Limitations of PDF (Portable Document Format) files for electronic journals…
Scott, Michael L
Thoroughly updated to reflect the most current developments in language design and implementation, the second edition*Addresses key developments in programming language design:+ Finalized C99 standard+ Java 5+ C# 2.0+ Java concurrency package (JSR 166) and comparable mechanisms in C#+ Java and C# generics*Introduces and discusses scripting languages throughout the book and in an entire new chapter that covers:+ Application domains: shell languages, text processing and report generation, mathematics and statistics, "glue" languages and general purpose scripting, extension languages, scripting t
Dewees, Christopher M.; Hooper, Jon K.
A variety of informational material for a course in marine biology or oceanology at the secondary level is presented. Among the topics discussed are: food webs and pyramids, planktonic blooms, marine life, plankton nets, food chains, phytoplankton, zooplankton, larval plankton and filter feeders. (BT)
Abstract. In this paper we present a qualitative outlook of mesoscopic biology where the typical length scale is of the order of nanometers and the energy scales comparable to thermal energy. Novel biomolecular machines, governed by coded information at the level of DNA and proteins, operate at these length scales in ...
Descriptions and interpretations of the natural world are dominated by dichotomies such as organism vs. environment, nature vs. nurture, genetic vs. epigenetic, but in the last couple of decades strong dissatisfaction with those partitions has been repeatedly voiced and a number of alternative perspectives have been suggested, from perspectives such as Dawkins' extended phenotype, Turner's extended organism, Oyama's Developmental Systems Theory and Odling-Smee's niche construction theory. Last in time is the description of biological phenomena in terms of hybrids between an organism (scaffolded system) and a living or non-living scaffold, forming unit systems to study processes such as reproduction and development. As scaffold, eventually, we can define any resource used by the biological system, especially in development and reproduction, without incorporating it as happens in the case of resources fueling metabolism. Addressing biological systems as functionally scaffolded systems may help pointing to functional relationships that can impart temporal marking to the developmental process and thus explain its irreversibility; revisiting the boundary between development and metabolism and also regeneration phenomena, by suggesting a conceptual framework within which to investigate phenomena of regular hypermorphic regeneration such as characteristic of deer antlers; fixing a periodization of development in terms of the times at which a scaffolding relationship begins or is terminated; and promoting plant galls to legitimate study objects of developmental biology.
This paper discusses the biological degradation of non-radioactive organic material occurring in radioactive wastes. The biochemical steps are often performed using microbes or isolated enzymes in combination with chemical steps and the aim is to oxidise the carbon, hydrogen, nitrogen and sulphur to their respective oxides. (U.K.)
School Science Review, 1981
Outlines a variety of laboratory procedures, techniques, and materials including construction of a survey frame for field biology, a simple tidal system, isolation and applications of plant protoplasts, tropisms, teaching lung structure, and a key to statistical methods for biologists. (DS)
Adoniou, Misty; Qing, Yi
There is a correlation between language proficiency and achievement in mathematics (Riordain & O'Donoghue, 2009), and this is particularly evident for children who speak English as an additional language or dialect. More effort needs to be made in mathematics classrooms to develop cognitive competencies, including the ability to decode and…
Tolk, Andreas; Galvin, Kevin; Hieb, Michael; Khimeche, Lionel
Battle Management Language (BML) is being developed as an unambiguous language to command and control forces and equipment conducting military operations and to provide for situational awareness and a shared common operational picture...
Sanden, Guro Refsum
This paper offers a review of existing literature on the topic of language management tools – the means by which language is managed – in multilingual organisations. By drawing on a combination of sociolinguistics and international business and management studies, a new taxonomy of language...... management tools is proposed, differentiating between three categories of tools. Firstly, corporate policies are the deliberate control of issues pertaining to language and communication developed at the managerial level of a firm. Secondly, corporate measures are the planned activities the firm’s leadership...... may deploy in order to address the language needs of the organisation. Finally, front-line practices refer to the use of informal, emergent language management tools available to staff members. The language management tools taxonomy provides a framework for operationalising the management of language...
Sanden, Guro Refsum
This paper offers a review of literature dealing with language policies in general and corporate language policies in particular. Based on a discussion of various definitions of these concepts within two research traditions, i.e. sociolinguistics and international management, a three......-level definition of corporate language policies is presented, emphasising that a corporate language policy is a context-specific policy about language use. The three-level definition is based on the argument that in order to acquire a complete understanding of what corporate language policies involve, one needs...... to consider three progressive questions; 1) what is a policy? 2) what is a language policy?, and ultimately, 3) what is a corporate language policy?...
This paper describes some strategies of teaching English language. Special attention was paid to adult learning, writing problem and some others. The aim of the paper is to show advantages of intensive learning of English language
... Are Here: Home → Multiple Languages → All Health Topics → Dual Diagnosis URL of this page: https://medlineplus.gov/ ... V W XYZ List of All Topics All Dual Diagnosis - Multiple Languages To use the sharing features ...
Ekman, Torbjörn; Mechlenborg, Peter; Schultz, Ulrik Pagh
Virtual machines raise the abstraction level of the execution environment at the cost of restricting the set of supported languages. Moreover, the ability of a language implementation to integrate with other languages hosted on the same virtual machine typically constrains the features...... of the language. In this paper, we present a highly flexible yet efficient approach to hosting multiple programming languages on an object-oriented virtual machine. Our approach is based on extending the interface of each class with language-specific wrapper methods, offering each language a tailored view...... of a given class. This approach can be deployed both on a statically typed virtual machine, such as the JVM, and on a dynamic virtual machine, such as a Smalltalk virtual machine. We have implemented our approach to language interoperability on top of a prototype virtual machine for embedded systems based...
Sanden, Guro Refsum
This paper offers a review of literature dealing with language policies in general and corporate language policies in particular. Based on a discussion of various definitions of these concepts within two research traditions, i.e. sociolinguistics and international management, a three......-level definition of corporate language policies is presented, emphasising that a corporate language policy is a context-specific policy about language use. The three-level definition is based on the argument that in order to acquire a complete understanding of what corporate language policies involve, one needs...... to consider three progressive questions; 1) what is a policy? 2) what is a language policy?, and ultimately, 3) what is a corporate language policy?...
... Are Here: Home → Multiple Languages → All Health Topics → Salmonella Infections URL of this page: https://medlineplus.gov/ ... V W XYZ List of All Topics All Salmonella Infections - Multiple Languages To use the sharing features ...
... from the intermixing of local sign languages and French Sign Language (LSF, or Langue des Signes Française). ... phrases with similar neural mechanisms as when we speak, new study finds New York University ( 4/03/ ...
... Are Here: Home → Multiple Languages → All Health Topics → Rotavirus Infections URL of this page: https://medlineplus.gov/ ... V W XYZ List of All Topics All Rotavirus Infections - Multiple Languages To use the sharing features ...
Sanden, Guro Refsum
into the Language Management Theory (LMT). A second definition of language management, diverting from LMT, can be found in the work of Spolsky, who treats language management as a theoretical component of the wider concept of language policy. Furthermore, over the past 15 years a number of scholars, particularly...... definitions of language management, before discussing five main focus points, which may be used to highlight their analytical differences.......The term ‘language management’ has become a widely used expression in the sociolinguistic literature. Originally introduced by Jernudd and Neustupný in 1987, as a novel continuation of the language planning tradition stemming from the 1960/70s, language management along these lines has developed...
Virginia R. Heslinga
Full Text Available Problems in attaining language mastery with students from diverse language backgrounds and levels of ability confront educators around the world. Experiments, research, and experience see positive effects of adding sign language in communication methods to pre-school and K-12 education. Augmentative, alternative, interactive, accommodating, and enriching strategies using sign language aid learners in balancing the skills needed to mastery of one language or multiple languages. Theories of learning that embrace play, drama, motion, repetition, socializing, and self-efficacy connect to the options for using sign language with learners in inclusive and mainstream classes. The methodical use of sign language by this researcher-educator over two and a half decades showed signing does build thinking skills, add enjoyment, stimulate communication, expand comprehension, increase vocabulary acquisition, encourage collaboration, and helps build appreciation for cultural diversity.
Pann Yu Mon; Yoshiki Mikami
With the enormous growth of the World Wide Web, search engines play a critical role in retrieving information from the borderless Web. Although many search engines are available for the major languages, but they are not much proficient for the less computerized languages including Myanmar. The main reason is that those search engines are not considering the specific features of those languages. A search engine which capable of searching the Web documents written in those languages is highly n...
There have been a lot of discussions of the origin of language. Some people think that the origin of words is onomatopoeias. Meanwhile, according to expressive theories, the origin of words and language is the innate cries of pain or pleasure produced by nonhuman animals. Others insist that language originated as a means of communication. Another theory holds that a learned vocalization systems, more like birdsong than innate calls, formed a middle term in language evolution. Others claim tha...
Most operating systems are written in the C programming language. Similar is with system software, for example, device drivers, compilers, debuggers, disk checkers, etc. Recently some new programming languages emerged, which are supposed to be suitable for system programming. In this thesis we present programming languages D, Go, Nim and Rust. We defined the criteria which are important for deciding whether programming language is suitable for system programming. We examine programming langua...
Costa, Alessandra; Naranjo, Juan Diego; Londono, Ricardo; Badylak, Stephen F
Biologic scaffold materials composed of allogeneic or xenogeneic extracellular matrix are commonly used for the repair and functional reconstruction of injured and missing tissues. These naturally occurring bioscaffolds are manufactured by the removal of the cellular content from source tissues while preserving the structural and functional molecular units of the remaining extracellular matrix (ECM). The mechanisms by which these bioscaffolds facilitate constructive remodeling and favorable clinical outcomes include release or creation of effector molecules that recruit endogenous stem/progenitor cells to the site of scaffold placement and modulation of the innate immune response, specifically the activation of an anti-inflammatory macrophage phenotype. The methods by which ECM biologic scaffolds are prepared, the current understanding of in vivo scaffold remodeling, and the associated clinical outcomes are discussed in this article. Copyright © 2017 Cold Spring Harbor Laboratory Press; all rights reserved.
Dogac, Asuman; Kabak, Yildiray; Namli, Tuncay; Okcan, Alper
Integrating healthcare enterprise (IHE) specifies integration profiles describing selected real world use cases to facilitate the interoperability of healthcare information resources. While realizing a complex real-world scenario, IHE profiles are combined by grouping the related IHE actors. Grouping IHE actors implies that the associated business processes (IHE profiles) that the actors are involved must be combined, that is, the choreography of the resulting collaborative business process must be determined by deciding on the execution sequence of transactions coming from different profiles. There are many IHE profiles and each user or vendor may support a different set of IHE profiles that fits to its business need. However, determining the precedence of all the involved transactions manually for each possible combination of the profiles is a very tedious task. In this paper, we describe how to obtain the overall business process automatically when IHE actors are grouped. For this purpose, we represent the IHE profiles through a standard, machine-processable language, namely, Organization for the Advancement of Structured Information Standards (OASIS) ebusiness eXtensible Markup Language (ebXML) Business Process Specification (ebBP) Language. We define the precedence rules among the transactions of the IHE profiles, again, in a machine-processable way. Then, through a graphical tool, we allow users to select the actors to be grouped and automatically produce the overall business process in a machine-processable format.
Stefanescu, Ioan; Titescu, Gheorghe; Tamaian, Radu; Haulica, Ion; Bild, Walther
According to the patent description, the biological radioprotector is deuterium depleted water, DDW, produced by vacuum distillation with an isotopic content lower than natural value. It appears as such or in a mixture with natural water and carbon dioxide. It can be used for preventing and reducing the ionizing radiation effects upon humans or animal organisms, exposed therapeutically, professionally or accidentally to radiation. The most significant advantage of using DDW as biological radioprotector results from its way of administration. Indeed no one of the radioprotectors currently used today can be orally administrated, what reduces the patients' compliance to prophylactic administrations. The biological radioprotector is an unnoxious product obtained from natural water, which can be administrated as food additive instead of drinking water. Dose modification factor is according to initial estimates around 1.9, what is a remarkable feature when one takes into account that the product is toxicity-free and side effect-free and can be administrated prophylactically as a food additive. A net radioprotective action of the deuterium depletion was evidenced experimentally in laboratory animals (rats) hydrated with DDW of 30 ppm D/(D+H) concentration as compared with normally hydrated control animals. Knowing the effects of irradiation and mechanisms of the acute radiation disease as well as the effects of administration of radiomimetic chemicals upon cellular lines of fast cell division, it appears that the effects of administrating DDW result from stimulation of the immunity system. In conclusion, the biological radioprotector DDW presents the following advantages: - it is obtained from natural products without toxicity; - it is easy to be administrated as a food additive, replacing the drinking water; - besides radioprotective effects, the product has also immunostimulative and antitumoral effects
Belnap, Jayne; Elias, Scott A.
Biological soil crusts, a community of cyanobacteria, lichens, mosses, and fungi, are an essential part of dryland ecosystems. They are critical in the stabilization of soils, protecting them from wind and water erosion. Similarly, these soil surface communities also stabilized soils on early Earth, allowing vascular plants to establish. They contribute nitrogen and carbon to otherwise relatively infertile dryland soils, and have a strong influence on hydrologic cycles. Their presence can also influence vascular plant establishment and nutrition.
Full Text Available BACKGROUND: Languages differ greatly both in their syntactic and morphological systems and in the social environments in which they exist. We challenge the view that language grammars are unrelated to social environments in which they are learned and used. METHODOLOGY/PRINCIPAL FINDINGS: We conducted a statistical analysis of >2,000 languages using a combination of demographic sources and the World Atlas of Language Structures--a database of structural language properties. We found strong relationships between linguistic factors related to morphological complexity, and demographic/socio-historical factors such as the number of language users, geographic spread, and degree of language contact. The analyses suggest that languages spoken by large groups have simpler inflectional morphology than languages spoken by smaller groups as measured on a variety of factors such as case systems and complexity of conjugations. Additionally, languages spoken by large groups are much more likely to use lexical strategies in place of inflectional morphology to encode evidentiality, negation, aspect, and possession. Our findings indicate that just as biological organisms are shaped by ecological niches, language structures appear to adapt to the environment (niche in which they are being learned and used. As adults learn a language, features that are difficult for them to acquire, are less likely to be passed on to subsequent learners. Languages used for communication in large groups that include adult learners appear to have been subjected to such selection. Conversely, the morphological complexity common to languages used in small groups increases redundancy which may facilitate language learning by infants. CONCLUSIONS/SIGNIFICANCE: We hypothesize that language structures are subjected to different evolutionary pressures in different social environments. Just as biological organisms are shaped by ecological niches, language structures appear to adapt to the
Okura, Eve K.
This dissertation presents the findings from interviews conducted with language nest workers, teachers, language nest coordinators, administrators of language revitalization programs, principals and directors of language immersion schools that work in close proximity with language nests, and linguists involved in language revitalization efforts.…
Mason, David G.
This article promotes the utilization of Sign Language of the Deaf as a primary and secondary research language. The article discusses English as the traditional research language, the role of sign language in bilingualism, possible uses for American Sign Language (ASL) as a research language, and the availability of ASL-based literature for…
Thurman, H.V.; Webber, H.H.
This book discusses both taxonomic and ecological topics on marine biology. Full coverage of marine organisms of all five kingdoms is provided, along with interesting and thorough discussion of all major marine habitats. Organization into six major parts allows flexibility. It also provides insight into important topics such as disposal of nuclear waste at sea, the idea that life began on the ocean floor, and how whales, krill, and people interact. A full-color photo chapter reviews questions, and exercises. The contents are: an overview marine biology: fundamental concepts/investigating life in the ocean; the physical ocean, the ocean floor, the nature of water, the nature and motion of ocean water; general ecology, conditions for life in the sea, biological productivity and energy transfer; marine organisms; monera, protista, mycota and metaphyta; the smaller marine animals, the large animals marine habitats, the intertidal zone/benthos of the continental shelf, the photic zone, the deep ocean, the ocean under stress, marine pollution, appendix a: the metric system and conversion factors/ appendix b: prefixes and suffixes/ appendix c: taxonomic classification of common marine organisms, and glossary, and index
Of the approximately 7,000 languages spoken today, some 2,500 are generally considered endangered. Here we argue that this consensus figure vastly underestimates the danger of digital language death, in that less than 5% of all languages can still ascend to the digital realm. We present evidence of a massive die-off caused by the digital divide. PMID:24167559
Full Text Available Of the approximately 7,000 languages spoken today, some 2,500 are generally considered endangered. Here we argue that this consensus figure vastly underestimates the danger of digital language death, in that less than 5% of all languages can still ascend to the digital realm. We present evidence of a massive die-off caused by the digital divide.
This paper surveys the research methods and approaches used in the multidisciplinary field of applied language studies or language education over the last fourty years. Drawing on insights gained in psycho- and sociolinguistics, educational linguistics and linguistic anthropology with regard to language and culture, it is organized around five…
Full Text Available This paper focuses on the idea of an effective communication between teacher and students aiming to prove that classroom activities maximize opportunities for learners to use target language in a communicative way for meaningful activities. The emphasis lies on meaning (messages they are creating or tasks they are completing rather than form (correctness of language and language structure.
Novak-Lukanovic, Sonja; Limon, David
The historical background, political changes, migration processes, EU membership and the current socio-linguistic situation have all influenced language policy and language planning in Slovenia. This article presents the most important aspects of language policy in Slovenia with a focus on the concept of linguistic diversity. The ethnic make-up of…
Over the years attempts have been made to standardize sign languages. This form of language planning has been tackled by a variety of agents, most notably teachers of Deaf students, social workers, government agencies, and occasionally groups of Deaf people themselves. Their efforts have most often involved the development of sign language books…
Hermes, Mary; Bang, Megan; Marin, Ananda
Endangered Indigenous languages have received little attention within the American educational research community. However, within Native American communities, language revitalization is pushing education beyond former iterations of culturally relevant curriculum and has the potential to radically alter how we understand culture and language in…
Feldman, G. H.; Johnson, J. A.
Structural-programming language is especially-tailored for producing assembly language programs for MODCOMP II and IV mini-computes. Modern programming language consists of set of simple and powerful control structures that include sequencing alternative selection, looping, sub-module linking, comment insertion, statement continuation, and compilation termination capabilities.
The relationship between minorities and language is complicated and related to the development of nation-states. Language minorities, as a social group, are distinguished from minority languages. The definition of minority is problematic. The size of a minority can differ widely. For membership,
Myth is the breakthrough point of [Ernest] Cassirer's philosophy; Art is one of key words to understand his defined language; and Symbolism infiltrates into all aspects of human cultures especially language. The shift of Cassirer from great theories of science and philosophy to the world of art, language, myth, and culture mirrors his bold and…
... Health Info » Voice, Speech, and Language Speech and Language Developmental Milestones On this page: How do speech ... and language developmental milestones? How do speech and language develop? The first 3 years of life, when ...
Alberts, Bruce; Lewis, Julian
Molecular Biology of the Cell is the classic in-dept text reference in cell biology. By extracting the fundamental concepts from this enormous and ever-growing field, the authors tell the story of cell biology, and create a coherent framework through which non-expert readers may approach the subject. Written in clear and concise language, and beautifully illustrated, the book is enjoyable to read, and it provides a clear sense of the excitement of modern biology. Molecular Biology of the Cell sets forth the current understanding of cell biology (completely updated as of Autumn 2001), and it explores the intriguing implications and possibilities of the great deal that remains unknown. The hallmark features of previous editions continue in the Fourth Edition. The book is designed with a clean and open, single-column layout. The art program maintains a completely consistent format and style, and includes over 1,600 photographs, electron micrographs, and original drawings by the authors. Clear and concise concept...
Full Text Available A systematic review of literature up to date reflects great scholarly interest in the impacts of study abroad (SA sojourns on foreign language learners’ communicative competence. This paper provides an overview on gains in sociolinguistic and pragmatic competences drawing upon research carried out in this field, which in broad terms supports the belief that both types of competences are effectively developed in SA stays. This article also offers a detailed account of the main constituents of the language tourism product -the travel component and the language learning component- with a special focus on the educational input and the language learning complements included in the latter. Thus, a fundamental part of the language tourism market system will be depicted from a supply perspective. Following an exploratory approach, a literature review was conducted in order to identify existing and missing knowledge in the field of language travel supply, and key aspects were pinpointed and classified. The taxonomy and underpinning concepts resulting from the categorisation of those key features may be considered the starting point for future investigations on SA programmes. The model offered in this exploratory study aims at constituting the underlying conceptual framework for subsequent research on the role of different SA programme design characteristics within the language tourism experience.
Hauser, Marc D.; Yang, Charles; Berwick, Robert C.; Tattersall, Ian; Ryan, Michael J.; Watumull, Jeffrey; Chomsky, Noam; Lewontin, Richard C.
Understanding the evolution of language requires evidence regarding origins and processes that led to change. In the last 40 years, there has been an explosion of research on this problem as well as a sense that considerable progress has been made. We argue instead that the richness of ideas is accompanied by a poverty of evidence, with essentially no explanation of how and why our linguistic computations and representations evolved. We show that, to date, (1) studies of nonhuman animals provide virtually no relevant parallels to human linguistic communication, and none to the underlying biological capacity; (2) the fossil and archaeological evidence does not inform our understanding of the computations and representations of our earliest ancestors, leaving details of origins and selective pressure unresolved; (3) our understanding of the genetics of language is so impoverished that there is little hope of connecting genes to linguistic processes any time soon; (4) all modeling attempts have made unfounded assumptions, and have provided no empirical tests, thus leaving any insights into language's origins unverifiable. Based on the current state of evidence, we submit that the most fundamental questions about the origins and evolution of our linguistic capacity remain as mysterious as ever, with considerable uncertainty about the discovery of either relevant or conclusive evidence that can adjudicate among the many open hypotheses. We conclude by presenting some suggestions about possible paths forward. PMID:24847300
Hauser, Marc D; Yang, Charles; Berwick, Robert C; Tattersall, Ian; Ryan, Michael J; Watumull, Jeffrey; Chomsky, Noam; Lewontin, Richard C
Understanding the evolution of language requires evidence regarding origins and processes that led to change. In the last 40 years, there has been an explosion of research on this problem as well as a sense that considerable progress has been made. We argue instead that the richness of ideas is accompanied by a poverty of evidence, with essentially no explanation of how and why our linguistic computations and representations evolved. We show that, to date, (1) studies of nonhuman animals provide virtually no relevant parallels to human linguistic communication, and none to the underlying biological capacity; (2) the fossil and archaeological evidence does not inform our understanding of the computations and representations of our earliest ancestors, leaving details of origins and selective pressure unresolved; (3) our understanding of the genetics of language is so impoverished that there is little hope of connecting genes to linguistic processes any time soon; (4) all modeling attempts have made unfounded assumptions, and have provided no empirical tests, thus leaving any insights into language's origins unverifiable. Based on the current state of evidence, we submit that the most fundamental questions about the origins and evolution of our linguistic capacity remain as mysterious as ever, with considerable uncertainty about the discovery of either relevant or conclusive evidence that can adjudicate among the many open hypotheses. We conclude by presenting some suggestions about possible paths forward.
Thomas, James; Kirby, Simon
We set out an account of how self-domestication plays a crucial role in the evolution of language. In doing so, we focus on the growing body of work that treats language structure as emerging from the process of cultural transmission . We argue that a full recognition of the importance of cultural transmission fundamentally changes the kind of questions we should be asking regarding the biological basis of language structure. If we think of language structure as reflecting an accumulated set of changes in our genome, then we might ask something like, "What are the genetic bases of language structure and why were they selected?" However, if cultural evolution can account for language structure, then this question no longer applies. Instead, we face the task of accounting for the origin of the traits that enabled that process of structure-creating cultural evolution to get started in the first place. In light of work on cultural evolution, then, the new question for biological evolution becomes, "How did those precursor traits evolve?" We identify two key precursor traits: (1) the transmission of the communication system through learning ; and (2) the ability to infer the communicative intent associated with a signal or action. We then describe two comparative case studies-the Bengalese finch and the domestic dog-in which parallel traits can be seen emerging following domestication . Finally, we turn to the role of domestication in human evolution. We argue that the cultural evolution of language structure has its origin in an earlier process of self-domestication.
Davison, Andrew P; Hines, Michael L; Muller, Eilif
Neuroscience simulators allow scientists to express models in terms of biological concepts, without having to concern themselves with low-level computational details of their implementation. The expressiveness, power and ease-of-use of the simulator interface is critical in efficiently and accurately translating ideas into a working simulation. We review long-term trends in the development of programmable simulator interfaces, and examine the benefits of moving from proprietary, domain-specific languages to modern dynamic general-purpose languages, in particular Python, which provide neuroscientists with an interactive and expressive simulation development environment and easy access to state-of-the-art general-purpose tools for scientific computing.
Scott, Michael L
Programming Language Pragmatics is the most comprehensive programming language textbook available today. Taking the perspective that language design and language implementation are tightly interconnected, and that neither can be fully understood in isolation, this critically acclaimed and bestselling book has been thoroughly updated to cover the most recent developments in programming language design. With a new chapter on run-time program management and expanded coverage of concurrency, this new edition provides both students and professionals alike with a solid understanding of the most impo
Burow, Burkhard D.
Computing in the next millennium will be using software from this millennium. Programming languages evolve and new ones continue to be created. The use of legacy code demonstrates why some present and future applications may span programming languages. Even a completely new application may mix programming languages, if it allows its components to be more conveniently expressed. Given the need, mixed language programming should be easy and robust. By resolving a variety of difficulties, the well established cfortran.h package provides, the desired convenient interface across the C and Fortran programming languages, as demonstrated using CERN's Book. (author)
Organick, Elliott Irving; Plummer, Robert P
Programming Language Structures deals with the structures of programming languages and introduces the reader to five important programming languages: Algol, Fortran, Lisp, Snobol, and Pascal. The fundamental similarities and differences among these languages are discussed. A unifying framework is constructed that can be used to study the structure of other languages, such as Cobol, PL/I, and APL. Several of the tools and methodologies needed to construct large programs are also considered.Comprised of 10 chapters, this book begins with a summary of the relevant concepts and principles about al
Visual languages have long been a pursuit of effective communication between human and machine. With rapid advances of the Internet and Web technology, human-human communication through the Web or electronic mobile devices is becoming more and more prevalent. Visual Languages and Applications is a comprehensive introduction to diagrammatical visual languages. This book discusses what visual programming languages are, and how such languages and their underlying foundations can be usefully applied to other fields in computer science. It also covers a broad range of contents from the underlying t
Full Text Available The criticism of the current language in school textbooks indicates the gravity of this problem in our environment and the need to solve it. The first step in approaching this problem is studying the reception of primary school textbooks. In the first part of the paper we discuss all primary school textbooks from the fifth to the eighth grade with regard to the frequency of textbook usage and the perception of the difficulty of textbook language. In the second part of the paper there is an additional analysis of history, geography, biology, physics and chemistry textbooks from the fifth to the eighth grade with regard to the reasons for which pupils find them difficult. This preliminary research comprised in total 120 pupils from an urban school, thirty from each fifth to eighth grade. We analyzed the textbooks of the Institute for Textbook Publishing and Teaching Aids, which are used most frequently in our educational practice, and hence can represent the general situation of the problem. Bearing in mind the limited size of the sample of pupils, the results are used only as an illustration and should encourage new studies on a more extensive sample. Textbook language is often difficult since it is mostly insufficiently comprehensible, longwinded and with many data. In natural sciences, physics and chemistry, pupils give up studying from the textbook. The textbooks in narrative subjects lead the way with respect to their usage, among which everybody finds history textbooks most difficult. Geography and biology textbooks were evaluated differently, depending on the grade and success of the pupils declaring themselves. The results present a guideline to the current and new writers of our textbooks, critics and publishing houses.
Hall, Matthew L; Ferreira, Victor S; Mayberry, Rachel I
Psycholinguistic studies of sign language processing provide valuable opportunities to assess whether language phenomena, which are primarily studied in spoken language, are fundamentally shaped by peripheral biology. For example, we know that when given a choice between two syntactically permissible ways to express the same proposition, speakers tend to choose structures that were recently used, a phenomenon known as syntactic priming. Here, we report two experiments testing syntactic priming of a noun phrase construction in American Sign Language (ASL). Experiment 1 shows that second language (L2) signers with normal hearing exhibit syntactic priming in ASL and that priming is stronger when the head noun is repeated between prime and target (the lexical boost effect). Experiment 2 shows that syntactic priming is equally strong among deaf native L1 signers, deaf late L1 learners, and hearing L2 signers. Experiment 2 also tested for, but did not find evidence of, phonological or semantic boosts to syntactic priming in ASL. These results show that despite the profound differences between spoken and signed languages in terms of how they are produced and perceived, the psychological representation of sentence structure (as assessed by syntactic priming) operates similarly in sign and speech.
Hall, Matthew L.; Ferreira, Victor S.; Mayberry, Rachel I.
Psycholinguistic studies of sign language processing provide valuable opportunities to assess whether language phenomena, which are primarily studied in spoken language, are fundamentally shaped by peripheral biology. For example, we know that when given a choice between two syntactically permissible ways to express the same proposition, speakers tend to choose structures that were recently used, a phenomenon known as syntactic priming. Here, we report two experiments testing syntactic priming of a noun phrase construction in American Sign Language (ASL). Experiment 1 shows that second language (L2) signers with normal hearing exhibit syntactic priming in ASL and that priming is stronger when the head noun is repeated between prime and target (the lexical boost effect). Experiment 2 shows that syntactic priming is equally strong among deaf native L1 signers, deaf late L1 learners, and hearing L2 signers. Experiment 2 also tested for, but did not find evidence of, phonological or semantic boosts to syntactic priming in ASL. These results show that despite the profound differences between spoken and signed languages in terms of how they are produced and perceived, the psychological representation of sentence structure (as assessed by syntactic priming) operates similarly in sign and speech. PMID:25786230
Matthew L Hall
Full Text Available Psycholinguistic studies of sign language processing provide valuable opportunities to assess whether language phenomena, which are primarily studied in spoken language, are fundamentally shaped by peripheral biology. For example, we know that when given a choice between two syntactically permissible ways to express the same proposition, speakers tend to choose structures that were recently used, a phenomenon known as syntactic priming. Here, we report two experiments testing syntactic priming of a noun phrase construction in American Sign Language (ASL. Experiment 1 shows that second language (L2 signers with normal hearing exhibit syntactic priming in ASL and that priming is stronger when the head noun is repeated between prime and target (the lexical boost effect. Experiment 2 shows that syntactic priming is equally strong among deaf native L1 signers, deaf late L1 learners, and hearing L2 signers. Experiment 2 also tested for, but did not find evidence of, phonological or semantic boosts to syntactic priming in ASL. These results show that despite the profound differences between spoken and signed languages in terms of how they are produced and perceived, the psychological representation of sentence structure (as assessed by syntactic priming operates similarly in sign and speech.
McMonigal, K. A.; Pietrzyk, R. A.; Sams, C. F.; Johnson, M. A.
The NASA Biological Specimen Repository (NBSR) was established in 2006 to collect, process, preserve and distribute spaceflight-related biological specimens from long duration ISS astronauts. This repository provides unique opportunities to study longitudinal changes in human physiology spanning may missions. The NBSR collects blood and urine samples from all participating ISS crewmembers who have provided informed consent. These biological samples are collected once before flight, during flight scheduled on flight days 15, 30, 60, 120 and within 2 weeks of landing. Postflight sessions are conducted 3 and 30 days after landing. The number of in-flight sessions is dependent on the duration of the mission. Specimens are maintained under optimal storage conditions in a manner that will maximize their integrity and viability for future research The repository operates under the authority of the NASA/JSC Committee for the Protection of Human Subjects to support scientific discovery that contributes to our fundamental knowledge in the area of human physiological changes and adaptation to a microgravity environment. The NBSR will institute guidelines for the solicitation, review and sample distribution process through establishment of the NBSR Advisory Board. The Advisory Board will be composed of representatives of all participating space agencies to evaluate each request from investigators for use of the samples. This process will be consistent with ethical principles, protection of crewmember confidentiality, prevailing laws and regulations, intellectual property policies, and consent form language. Operations supporting the NBSR are scheduled to continue until the end of U.S. presence on the ISS. Sample distribution is proposed to begin with selections on investigations beginning in 2017. The availability of the NBSR will contribute to the body of knowledge about the diverse factors of spaceflight on human physiology.
Jorge-Herrero, E. [Servicio de Cirugia Experimental. Clinica Puerta de Hierro, Madrid (Spain)
There are a number of situations in which substances of biological origin are employed as biomaterials. Most of them are macromolecules derived from isolated connective tissue or the connective tissue itself in membrane form, in both cases, the tissue can be used in its natural form or be chemically treated. In other cases, certain blood vessels can be chemically pretreated and used as vascular prostheses. Proteins such as albumin, collagen and fibrinogen are employed to coat vascular prostheses. Certain polysaccharides have also been tested for use in controlled drug release systems. Likewise, a number of tissues, such as dura mater, bovine pericardium, procine valves and human valves, are used in the preparation of cardiac prostheses. We also use veins from animals or humans in arterial replacement. In none of these cases are the tissues employed dissimilar to the native tissues as they have been chemically modified, becoming a new bio material with different physical and biochemical properties. In short, we find that natural products are being utilized as biomaterials and must be considered as such; thus, it is necessary to study both their chemicobiological and physicomechanical properties. In the present report, we review the current applications, problems and future prospects of some of these biological biomaterials. (Author) 84 refs.
A distinction is made between attitudes and specifically language attitudes. The process of acculturation is dealt with and its influence upon the motivation of ESL learners. Integrational and instmmental motivation are defined. Teachers' language attitudes, the dangers of prejudice and stereotyping are discussed. ,Attitude changes are analysed as well as the teacher's role in effecting them. 'n Onderskeid word getref tussen algemene houdings en houdings ten opsigte van taal. Die proses van a...
Full Text Available The paper is dedicated to the problem of determination of the essence of language union and language family in modern linguistics, which is considered important, because these terms are often used as absolute synonyms. The research is relevant due to the need to distinguish the features of languages that are inherited during their functioning within either language union or language family when these languages are compared. The research has been carried out in order to present the historical background of the problem and to justify the need for differentiation of language facts that allow relating languages to particular language union or language family. In order to fulfill the goal of this work, descriptive, comparative, and historical methods have been used. A range of examples has been provided to prove that some languages, mainly Slavonic and Baltic languages, form a language family rather than a language union, because a whole number of features in their systems are the heritage of their common Indo-European past. Firstly, it is necessary to take into account changes having either common or different nature in the system of particular languages; secondly, one must have a precise idea of what features in the phonetic and morphological systems of compared languages allow to relate them to language union or language family; thirdly, it must be determined whether the changes in compared languages are regular or of any other type. On the basis of the obtained results, the following conclusions have been drawn: language union and language family are two different types of relations between modern languages; they allow identifying both degree of similarity of these languages and causes of differences between them. It is most important that one should distinguish and describe the specific features of two basic groups of languages forming language family or language union. The results obtained during the analysis are very important for linguistics
Lee Bih Ni; Kiu Su Na
This paper discusses the Chinese Language Teaching as a Second Language by focusing on Immersion Teaching. Researchers used narrative literature review to describe the current states of both art and science in focused areas of inquiry. Immersion teaching comes with a standard that teachers must reliably meet. Chinese language-immersion instruction consists of language and content lessons, including functional usage of the language, academic language, authentic language, and correct Chinese so...
Olga B. Akimova
Full Text Available The aim of the investigation is to denote the necessity of strengthening of the Russian language position as one of the strategic humanitarian priorities of the Russian Federation.Methods. The methods involve the analysis and generalisation of the documents’ content in the last two years, concerning problems of the Russian language and the Russian literature.Results. Since the beginning of the 21st century, Russia takes active and comprehensive measures to support the Russian language and its spread around the world. At the same time, the Russian Government has approved a number of relevant documents, established the Council on the Russian language under the Government of the Russian Federation, as well as established the Council on the Russian language under the President of the Russian Federation. The large-scale package of measures aimed at promotion of the Russian language as an official language and as a language of international communication, as well as at supporting the Russian language abroad, has been implemented in the framework of the three federal target Russian language programs. However, the analysis of implementation of the mentioned above programs, as well as received social effects and current practice does not provide relevant solutions for the major problems and does not always correspond to the rapidly changing realities.Practical significance. The perspective directions of the state language policy in the field of the Russian language and literature are specified and formulated: the analysis of the programs and projects aimed at the development, distribution and support of the Russian language; providing coordination of actions of executive authorities in the presented study; improvement of the Russian language studying quality in schools in accordance with features of the general education in the national republics; professional level improvement of teachers of the Russian language; preservation of national languages of
Following an introduction into the field of cellular radiation effect considering the most important experimental results, the biological significance of the colony formation ability is brought out. The inactivation concept of stem cells does not only prove to be good, according to the present results, in the interpretation of the pathogenesis of acute radiation effects on moult tissue, it also enables chronicle radiation injuries to be interpreted through changes in the fibrous part of the organs. Radiation therapy of tumours can also be explained to a large extent by the radiation effect on the unlimited reproductiveness of tumour cells. The more or less similar dose effect curves for healthy and tumour tissue in practice lead to intermittent irradiation. The dependence of the intermittent doses and intervals on factors such as Elkind recovery, synchronisation, redistribution, reoxygenation, repopulation and regeneration are reviewed. (ORU/LH) [de
McLeod, Carmen; Nerlich, Brigitte
Metaphors are not just decorative rhetorical devices that make speech pretty. They are fundamental tools for thinking about the world and acting on the world. The language we use to make a better world matters; words matter; metaphors matter. Words have consequences - ethical, social and legal ones, as well as political and economic ones. They need to be used 'responsibly'. They also need to be studied carefully - this is what we want to do through this editorial and the related thematic collection. In the context of synthetic biology, natural and social scientists have become increasingly interested in metaphors, a wave of interest that we want to exploit and amplify. We want to build on emerging articles and books on synthetic biology, metaphors of life and the ethical and moral implications of such metaphors. This editorial provides a brief introduction to synthetic biology and responsible innovation, as well as a comprehensive review of literature on the social, cultural and ethical impacts of metaphor use in genomics and synthetic biology. Our aim is to stimulate an interdisciplinary and international discussion on the impact that metaphors can have on science, policy and publics in the context of synthetic biology.
Kelly da Rocha Neves
Conclusion: The results showed a high prevalence of stunting and below‐average results for cognitive/language development among the participating children. Both environmental and biological factors were related to growth and development. However, biological variables showed a greater association with growth, whereas environmental variables were associated with development.
Huang, Biao; Jiang, Cizhong; Zhang, Rongxin
Epigenetics is one of the most rapidly developing fields of biological research. Breakthroughs in several technologies have enabled the possibility of genome-wide epigenetic research, for example the mapping of human genome-wide DNA methylation. In addition, with the development of various high-throughput and high-resolution sequencing technologies, a large number of functional noncoding RNAs have been identified. Massive studies indicated that these functional ncRNA also play an important role in epigenetics. In this review, we gain inspiration from the recent proposal of the ceRNAs hypothesis. This hypothesis proposes that miRNAs act as a language of communication. Accordingly, we further deduce that all of epigenetics may functionally acquire such a unique language characteristic. In summary, various epigenetic markers may not only participate in regulating cellular processes, but they may also act as the intracellular 'language' of communication and are involved in extensive information exchanges within cell.
Full Text Available Is the mirror neuron system (MNS used in language understanding? According to embodied accounts of language comprehension, understanding sentences describing actions makes use of neural mechanisms of action control, including the MNS. Consequently, repeatedly comprehending sentences describing similar actions should induce adaptation of the MNS thereby warping its use in other cognitive processes such as action recognition and prediction. To test this prediction, participants read blocks of multiple sentences where each sentence in the block described transfer of objects in a direction away or toward the reader. Following each block, adaptation was measured by having participants predict the end-point of videotaped actions. The adapting sentences disrupted prediction of actions in the same direction, but a only for videos of biological motion, and b only when the effector implied by the language (e.g., the hand matched the videos. These findings are signatures of the mirror neuron system.
Michael R. Levot
Full Text Available The Minimalist Program in generative syntax has been the subject of much rancour, a good proportion of it stoked by Noam Chomsky’s suggestion that language may represent “a ‘perfect solution’ to minimal design specifications.” A particular flash point has been the application of Minimalist principles to speculations about how language evolved in the human species. This paper argues that Minimalism is well supported as a plausible approach to language evolution. It is claimed that an assumption of minimal design specifications like that employed in MP syntax satisfies three key desiderata of evolutionary and general scientific plausibility: Physical Optimism, Rational Optimism, and Darwin’s Problem. In support of this claim, the methodologies employed in MP to maximise parsimony are characterised through an analysis of recent theories in Minimalist syntax, and those methodologies are defended with reference to practices and arguments from evolutionary biology and other natural sciences.
Iwazume, Michiaki; Kobayashi, Ichiro; Itho, Noriko; Takahashi, Yusuke; Fujishiro, Hiroko; Sugeno, Michio
The aim of this study is to provide all people, from small children to aged persons, with a computational environment for everyday language communication. In order to achieve this, we propose a framework for a language-based operating system. In this paper, we explain our approach to dealing with the meaning of language, the architecture of the language operating system and its components. In particular, we describe the notion of language protocol and its resource representation (i.e., semiotic base), compared to the other protocols and their resource representations. We argue that by processing meaning of language rather than processing information, we attempt to provide a more human-like computer system and an intelligent computational environment to all people.
Laursen, Helle Pia; Mogensen, Naja Dahlstrup
This article examines how, in a multilingual perspective, language competence is experienced, talked about and practiced by language users themselves. By viewing children as active co-creators of the spaces in which language is used, this article contributes to a research tradition in which focus...... multilingual children's language and literacy acquisition processes, we direct our focus to a single child's active exploration of what it means to know a language. Through analysis of interviews and researcher generated activities, we see how this child both describes and does language competence...... as a phenomenon that has several meanings, is social, is dependent on location and is unpredictable. Thus, we demonstrate how focus on the child's perspective of what it means to ‘know language’ can lead to insights into the creative, complex and dynamic processes that are part of children's active meaning making...
topics can cross-fertilize each other, and that our understanding of the issues can benefit from coverage that is global, reflective and committed. A website with additional resource material to this book can be found at http://babel.ruc.dk/-robert/. Brings together scholarship in language, education......This work brings together cutting-edge scholarship in language, education and society from all parts of the world. Celebrating the 60th birthday of Tove Skutnabb-Kangas, it is inspired by her work in minority, indigenous and immigrant education; multilingualism; linguistic human rights; and global...... language and power issues. Drawn from all parts of the world, the contributors are active in a range of scientific and professional areas including bilingual education; sociolinguistics; the sociology of education, law and language; economics and language; linguistics; sign language; racism; communication...
Chater, Nick; McCauley, Stewart M.; Christiansen, M. H.
occurs on-line. These properties are difficult to reconcile with the 'abstract knowledge' viewpoint, and crucially suggest that language comprehension and production are facets of a unitary skill. This viewpoint is exemplified in the Chunk-Based Learner, a computational acquisition model that processes...... incrementally and learns on-line. The model both parses and produces language; and implements the idea that language acquisition is nothing more than learning to process. We suggest that the Now-or-Never bottleneck also provides a strong motivation for unified perception-production models in other domains......Are comprehension and production a single, integrated skill, or are they separate processes drawing on a shared abstract knowledge of language? We argue that a fundamental constraint on memory, the Now-or-Never bottleneck, implies that language processing is incremental and that language learning...
Rossing, Niels Nygaard; Skrubbeltrang, Lotte Stausgaard
users embedded in different collective social institutions such as national cultures that affect their choices in game-playing situations. Thus, the actions of Italian, English and Brazilian players become different dialects within the same language system. These dialects are expressed in actions...... language to have two components: a language system and language users (Danesi, 2003). Consequently, football can be characterized as a language containing a system with specific rules of the game and users with actual choices and actions within the game. All football players can be considered language...... levels (Schein, 2004) in which each player and his actions can be considered an artefact - a concrete symbol in motion embedded in espoused values and basic assumptions. Therefore, the actions of each dialect are strongly connected to the underlying understanding of football. By document and video...
Monaghan, Padraic; Shillcock, Richard C.; Christiansen, Morten H.; Kirby, Simon
It is a long established convention that the relationship between sounds and meanings of words is essentially arbitrary—typically the sound of a word gives no hint of its meaning. However, there are numerous reported instances of systematic sound–meaning mappings in language, and this systematicity has been claimed to be important for early language development. In a large-scale corpus analysis of English, we show that sound–meaning mappings are more systematic than would be expected by chance. Furthermore, this systematicity is more pronounced for words involved in the early stages of language acquisition and reduces in later vocabulary development. We propose that the vocabulary is structured to enable systematicity in early language learning to promote language acquisition, while also incorporating arbitrariness for later language in order to facilitate communicative expressivity and efficiency. PMID:25092667
Hall, Graham; Cook, Guy
Until recently, the assumption of the language-teaching literature has been that new languages are best taught and learned monolingually, without the use of the students' own language(s). In recent years, however, this monolingual assumption has been increasingly questioned, and a re-evaluation of teaching that relates the language being taught to…
Bartolotti, James; Marian, Viorica
Learning a new language involves substantial vocabulary acquisition. Learners can accelerate this process by relying on words with native-language overlap, such as cognates. For bilingual third language learners, it is necessary to determine how their two existing languages interact during novel language learning. A scaffolding account predicts…
Svalberg, Agneta M.-L.
Following on from my state-of-the-art article on "Language Awareness and language learning" (Svalberg 2007), in this paper I will discuss specific research tasks which are centrally concerned with different aspects of language awareness (LA): "explicit knowledge about language, and conscious perception and sensitivity in language learning,…
Ó Flatharta, Peadar
The Irish language is recognised in Bunreacht na hÉireann [The Constitution of Ireland] as the national and first official language, and provisions to support the language are to found in c.120 specific enactments in Irish legislation. In 2007, the Irish language was designated as an official working language of the European Union. In 2003, the…
Rice, MaryJoe K; Ruder, Warren C
Synthetic biology is a new discipline that combines science and engineering approaches to precisely control biological networks. These signaling networks are especially important in fields such as biomedicine and biochemical engineering. Additionally, biological networks can also be critical to the production of naturally occurring biological nanomaterials, and as a result, synthetic biology holds tremendous potential in creating new materials. This review introduces the field of synthetic biology, discusses how biological systems naturally produce materials, and then presents examples and strategies for incorporating synthetic biology approaches in the development of new materials. In particular, strategies for using synthetic biology to produce both organic and inorganic nanomaterials are discussed. Ultimately, synthetic biology holds the potential to dramatically impact biological materials science with significant potential applications in medical systems.
Rice, MaryJoe K; Ruder, Warren C
Synthetic biology is a new discipline that combines science and engineering approaches to precisely control biological networks. These signaling networks are especially important in fields such as biomedicine and biochemical engineering. Additionally, biological networks can also be critical to the production of naturally occurring biological nanomaterials, and as a result, synthetic biology holds tremendous potential in creating new materials. This review introduces the field of synthetic biology, discusses how biological systems naturally produce materials, and then presents examples and strategies for incorporating synthetic biology approaches in the development of new materials. In particular, strategies for using synthetic biology to produce both organic and inorganic nanomaterials are discussed. Ultimately, synthetic biology holds the potential to dramatically impact biological materials science with significant potential applications in medical systems. (review)
This paper examines whether the recursive structure imbedded in some exercises used in the Non Verbal Communication Device (NVCD) approach is actually the factor that enables this approach to favor language acquisition and reacquisition in the case of children with cerebral lesions. For that a definition of the principle of recursion as it is used by logicians is presented. The two opposing approaches to the problem of language development are explained. For many authors such as Chomsky  the faculty of language is innate. This is known as the Standard Theory; the other researchers in this field, e.g. Bates and Elman , claim that language is entirely constructed by the young child: they thus speak of Language Acquisition. It is also shown that in both cases, a version of the principle of recursion is relevant for human language. The NVCD approach is defined and the results obtained in the domain of language while using this approach are presented: young subjects using this approach acquire a richer language structure or re-acquire such a structure in the case of cerebral lesions. Finally it is shown that exercises used in this framework imply the manipulation of recursive structures leading to regular grammars. It is thus hypothesized that language development could be favored using recursive structures with the young child. It could also be the case that the NVCD like exercises used with children lead to the elaboration of a regular language, as defined by Chomsky , which could be sufficient for language development but would not require full recursion. This double claim could reconcile Chomsky's approach with psychological observations made by adherents of the Language Acquisition approach, if it is confirmed by researches combining the use of NVCDs, psychometric methods and the use of Neural Networks. This paper thus suggests that a research group oriented towards this problematic should be organized.
Olga B. Akimova; Tatyana S. Tabachenko
The aim of the investigation is to denote the necessity of strengthening of the Russian language position as one of the strategic humanitarian priorities of the Russian Federation.Methods. The methods involve the analysis and generalisation of the documents’ content in the last two years, concerning problems of the Russian language and the Russian literature.Results. Since the beginning of the 21st century, Russia takes active and comprehensive measures to support the Russian language and its...
among parliamentarians. Nevertheless, we observe that language contact phenomena such as various forms of alternation between Swahili and. English occur quite regularly in parliamentary debates and submissions. The paradox however is that various forms of documentation in parliament are drafted in English.
Discusses problems associated with teaching physics in English and students' native languages. Reviews studies on the topic, including Whorf's linguistic relativity. Includes suggestions for further research. (SK)
This article discusses the two main types of trilingualism, individual trilingualism and societal trilingualism, or multilingualism. Research directions in third language learning are also noted. (CLK)
Shaykhian, Gholam Ali
C++ Programming Language: The C++ seminar covers the fundamentals of C++ programming language. The C++ fundamentals are grouped into three parts where each part includes both concept and programming examples aimed at for hands-on practice. The first part covers the functional aspect of C++ programming language with emphasis on function parameters and efficient memory utilization. The second part covers the essential framework of C++ programming language, the object-oriented aspects. Information necessary to evaluate various features of object-oriented programming; including encapsulation, polymorphism and inheritance will be discussed. The last part of the seminar covers template and generic programming. Examples include both user defined and standard templates.
Lauridsen, Karen M.
to determine the needs, the measures that are already in place, and the measures that need to be put in place in order for them to do so. The recommendations of the sections on pages 3‐11 are meant to assist HEI leadership and management teams in this process. These recommendations are collected here......(s) of communication at institutional / departmental / research group / administrative unit, etc. levels? What is/are the language(s) of instruction? Who are the HEI stakeholders / targets audiences, and which language(s) is / are used in communication with these audiences? HEIs should further consider...
Bloome, David; Beauchemin, Faythe
We explore how the languaging of everyday life in classrooms promulgates conceptions of personhood. We use the term "languaging" to argue for a shift from conceptions of language as a noun to languaging as a verb, a view of language as inseparable from and constitutive of the actions and reactions of people in response to each other. It…
"First language acquisition" commonly means the acquisition of a single language in childhood, regardless of the number of languages in a child's natural environment. Language acquisition is variously viewed as predetermined, wondrous, a source of concern, and as developing through formal processes. "First language teaching" concerns schooling in…
As an important input and teaching media in foreign language teaching classes, teacher talk (TT) has a great effect on language output. This paper explores the problems related to teacher talk (TT) and language output in practical ELT (English Language Teaching) classroom and presents some suggestions for solving the problems which affect learner' effective language output.
Pfau, R.; Steinbach, M.; Woll, B.
Sign language linguists show here that all the questions relevant to the linguistic investigation of spoken languages can be asked about sign languages. Conversely, questions that sign language linguists consider - even if spoken language researchers have not asked them yet - should also be asked of
Donoghue, Mildred R.; Kunkle, John F.
A book on second languages in primary education, designed to assist both classroom teachers and language specialists, is presented. The following topics are addressed: (1) reasons for studying a second language; (2) reasons for children to learn a second language; (3) language choices; (4) qualifications of teachers; (5) FLES, bilingual education,…
Full Text Available The field of language planning (LP has largely ignored planned languages. Of classic descriptions of LP processes, only Tauli (preceded by Wüster suggests that planned languages (what Wüster calls Plansprache might bear on LP theory and practice. If LP aims "to modify the linguistic behaviour of some community for some reason," as Kaplan and Baldauf put it, creating a language de novo is little different. Language policy and planning are increasingly seen as more local and less official, and occasionally more international and cosmopolitan. Zamenhof's work on Esperanto provides extensive material, little studied, documenting the formation of the language and linking it particularly to issues of supranational LP. Defining LP decision-making, Kaplan & Baldauf begin with context and target population. Zamenhof's Esperanto came shortly before Ben-Yehuda's revived Hebrew. His target community was (mostly the world's educated elite; Ben-Yehuda's was worldwide Jewry. Both planners were driven not by linguistic interest but by sociopolitical ideology rooted in reaction to anti-Semitism and imbued with the idea of progress. Their territories had no boundaries, but were not imaginary. Function mattered as much as form (Haugen's terms, status as much as corpus. For Zamenhof, status planning involved emphasis on Esperanto's ownership by its community - a collective planning process embracing all speakers (cf. Hebrew. Corpus planning included a standardized European semantics, lexical selectivity based not simply on standardization but on representation, and the development of written, and literary, style. Esperanto was successful as linguistic system and community language, less as generally accepted lingua franca. Its terminology development and language cultivation offers a model for language revival, but Zamenhof's somewhat limited analysis of language economy left him unprepared to deal with language as power.
Kirby, Simon; Dowman, Mike; Griffiths, Thomas L.
Human language arises from biological evolution, individual learning, and cultural transmission, but the interaction of these three processes has not been widely studied. We set out a formal framework for analyzing cultural transmission, which allows us to investigate how innate learning biases are related to universal properties of language. We show that cultural transmission can magnify weak biases into strong linguistic universals, undermining one of the arguments for strong innate constra...
Konishi, Haruka; Kanero, Junko; Freeman, Max R; Golinkoff, Roberta Michnick; Hirsh-Pasek, Kathy
The number of children growing up in dual language environments is increasing in the United States. Despite the apparent benefits of speaking two languages, children learning English as a second language (ESL) often face struggles, as they may experience poverty and impoverished language input at home. Early exposure to a rich language environment is crucial for ESL children's academic success. This article explores how six evidenced-based principles of language learning can be used to provide support for ESL children.
There is substantial evidence that the human language capacity (LC) is a species-specific biological property, essentially unique to humans, invariant among human groups, and dissociated from other cognitive systems. Each language, an instantiation of LC, consists of a generative procedure that yields a discrete infinity of hierarchically structured expressions with semantic interpretations, hence a kind of "language of thought" (LOT), along with an operation of externalization (EXT) to some sensory-motor system, typically sound. There is mounting evidence that generation of LOT observes language-independent principles of computational efficiency and is based on the simplest computational operations, and that EXT is an ancillary process not entering into the core semantic properties of LOT and is the primary locus of the apparent complexity, diversity, and mutability of language. These conclusions are not surprising, since the internal system is acquired virtually without evidence in fundamental respects, and EXT relates it to sensory-motor systems that are unrelated to it. Even such properties as the linear order of words appear to be reflexes of the sensory motor system, not available to generation of LOT. The limited evidence from the evolutionary record lends support to these conclusions, suggesting that LC emerged with Homo sapiens or not long after, and has not evolved since human groups dispersed.
Zhang, Menghan; Gong, Tao
It is generally difficult to define reasonable parameters and interpret their values in mathematical models of social phenomena. Rather than directly fitting abstract parameters against empirical data, we should define some concrete parameters to denote the sociocultural factors relevant for particular phenomena, and compute the values of these parameters based upon the corresponding empirical data. Taking the example of modeling studies of language competition, we propose a language diffusion principle and two language inheritance principles to compute two critical parameters, namely the impacts and inheritance rates of competing languages, in our language competition model derived from the Lotka-Volterra competition model in evolutionary biology. These principles assign explicit sociolinguistic meanings to those parameters and calculate their values from the relevant data of population censuses and language surveys. Using four examples of language competition, we illustrate that our language competition model with thus-estimated parameter values can reliably replicate and predict the dynamics of language competition, and it is especially useful in cases lacking direct competition data.
Serianni, Barbara; Rethwisch, Carolyn
This paper is the result of a language analysis research project focused on the Russian Language. The study included a diverse literature review that included published materials as well as online sources in addition to an interview with a native Russian speaker residing in the United States. Areas of study include the origin and history of the…
Morgan, Mary M.; Beaman, Peter D.; Shusman, Daniel J.; Hupp, Jon A.; Zielstorff, Rita D.; Barnett, G. Octo
This paper describes the Medical Query Language (MQL), a “formal” language which enables unsophisticated users, having no background in programming or computer science, to express information retrieval and analysis questions of their data bases. MQL is designed to access any MUMPS data base. Most MQL applications to date have dealt with the COmputer STored Ambulatory Record (COSTAR) data base.
on the attitude and humility of the doctor and much depends on language. As we pass through a world where technology and machinery replace the fundamentals of medical investigation, where notes contain phrases such as 'not sonographically or clinically appendicitis', basic skills are being lost. The use of language, the ...
Kats, L.C.L.; Visser, E.
Spoofax is a language workbench for efficient, agile development of textual domain-specific languages with state-of-the-art IDE support. It provides a comprehensive environment that integrates syntax definition, program transformation, code generation, and declarative specification of IDE components
Duane, Drake D., Ed.; Rawson, Margaret B., Ed.
The nine papers in this book discuss aspects of language processing that contribute to reading difficulty. After a summary of the 1974 World Congress on Dyslexia, at which these papers were presented, the following subjects are examined: historical background and educational treatment of dyslexia; the structure of language; neuroanatomy underlying…
Thomas, J.B.; Chambon, M.R.
The differences between human and computing languages are recalled. It is argued that they are to some extent structured in antagonistic ways. Languages in structural calculation, in the past, present, and future, are considered. The contribution of artificial intelligence is stressed [fr
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Honig, Lucille J.; Brod, Richard I.
Gives employment opportunity information in the following fields where foreign language can be used as an auxiliary skill: 1) Business, Industry, Commerce; 2) Civil Service; 3) Education; 4) Law; 5) Library Science; 6) Media; 7) Science; 8) Service; 9) Social Sciences; 10) Travel, Tourism. The fields of foreign language teaching and interpretation…
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Henle, Paul, Ed.
This book presents a collection of essays intended for an integrated study of language by anthropologists, literary critics, philosophers, psychologists, sociologists, and linguists. There is first a discussion of theories concerning the interrelationship of language, thought, and culture. This is followed by a discussion of the development of…
Nuessel, Frank H., Jr.
Suggests language used to depict the elderly is overwhelmingly negative. Points out many ageist terms are doubly offensive because they contain both ageist and sexist references. Urges the establishment of a set of guidelines for language usage in the various media to reduce ageism. (Author/RC)
This article argues that teaching politically correct language to English learners provides them with important information and opportunities to be exposed to cultural issues. The author offers a brief review of how political correctness became an issue and how being politically correct influences the use of language. The article then presents…
Hurley, Sarah Jessica; Murray, Alexa Lee; Cormas, Peter
This article describes a lesson taught in a designated English Language Learner (ELL) classroom in an elementary school in Pawtucket, Rhode Island, using a sheltered instruction approach. Eighty one percent of the students at this school are from diverse ethnic backgrounds where 25 per cent of them receive ELL services. A variety of languages are…
Postman, Neil, Ed.; And Others
The essays published in this collection were written in response to the basic question, "To what extent is the language of politics/advertising/psychotherapy/education/bureaucracy/etc. facilitating or impeding our chances of survival?" The general topic here is the contemporary use of language and the semantic environment in America, especially in…
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Hiddinga, A.; Crasborn, O.
Deaf people who form part of a Deaf community communicate using a shared sign language. When meeting people from another language community, they can fall back on a flexible and highly context-dependent form of communication called international sign, in which shared elements from their own sign
Considers characteristics of educational television that militate against effective language learning and argues that further research is needed to ascertain whether language development is promoted by educational television and which programs and formats are best. Research in the United States and suggestions for future research are discussed.…
Baker, Eva; And Others
This sourcebook is intended to provide researchers and users of natural language computer systems with a classification scheme to describe language-related problems associated with such systems. Methods from the disciplines of artificial intelligence (AI), education, linguistics, psychology, anthropology, and psychometrics were applied in an…
Coskun, Abdullah; Arslan, Abdullah
This paper aims to emphasize the importance of using Moodle in foreign language learning and teaching by reviewing relevant literature and introducing a Moodle-based environment aiming to help English learners to practice their English by themselves. Firstly, the use of Moodle in education and more specifically in English Language Teaching is…
A discussion of legal and administrative language, and the necessity for accurate translation of this language in the field of international relations. Topics treated are: characteristic features of legal and administrative terminology; the interpretation of it; and the technique of translating legal and administrative texts. (AMH)
The development of the national language of the Philippines is sketched from the initial selection of Tagalog to its standardization and propagation as national language and its renaming as Pilipino, subsequently Filipino. The intellectualization phase is examined as process and product and according to its psychological and sociological…
Teaching modern foreign languages is not all about communicative skills. It is also about testing functional abilities. While we still pay lip service to the creed of communicative language teaching, we have adopted test formats and teaching styles that follow a hidden agenda: the production of human capital. The main objective of teaching is…
Pedersen, Michael Svendsen; Frederiksen, Karen-Margrete; Jakobsen, Karen Sonne
The articles in this publication discuss theoretical issues in relation to the teaching/learning of a second language in the workplace and present practical experiences from workplace language programmes for immigrant workers carried out in a number of European countries....
This article explores India's linguistic diversity from a language policy perspective, emphasizing policies relevant to linguistic minorities. The Kumaun region of Utterakhand provides a local, minority-language perspective on national-level language planning. A look at the complexity of counting India's languages reveals language planning…
Ueno, Yutaka; Arita, Masanori; Kumagai, Toshitaka; Asai, Kiyoshi
The data processing language in a graphical software tool that manages sequence annotation data from genome databases should provide flexible functions for the tasks in molecular biology research. Among currently available languages we adopted the Lua programming language. It fulfills our requirements to perform computational tasks for sequence map layouts, i.e. the handling of data containers, symbolic reference to data, and a simple programming syntax. Upon importing a foreign file, the original data are first decomposed in the Lua language while maintaining the original data schema. The converted data are parsed by the Lua interpreter and the contents are stored in our data warehouse. Then, portions of annotations are selected and arranged into our catalog format to be depicted on the sequence map. Our sequence visualization program was successfully implemented, embedding the Lua language for processing of annotation data and layout script. The program is available at http://staff.aist.go.jp/yutaka.ueno/guppy/.
Steffensen, Sune Vork
addresses Linell’s critique of Distributed Language as rooted in biosemiotics and in theories of organism-environment systems. It is argued that Linell’s sense-based approach entails an individualist view of how conspecific Others acquire their status as prominent parts of the sense-maker’s environment......This article takes a starting point in Per Linell’s (2013) review article on the book Distributed Language (Cowley, 2011a) and other contributions to the field of ‘Distributed Language’, including Cowley et al. (2010) and Hodges et al. (2012). The Distributed Language approach is a naturalistic...... and anti-representational approach to language that builds on recent developments in the cognitive sciences. With a starting point in Linell’s discussion of the approach, the article aims to clarify four aspects of a distributed view of language vis-à-vis the tradition of Dialogism, as presented by Linell...
Full Text Available Learning a language means also the study of a different culture. This study focuses on the introduction of the topic of culture in language teaching into the curriculum of the subject Language Teaching Methodology for teacher trainees studying at Translation And Interpreting Studies, Sapientia Hungarian University of Transylvania, Faculty of Technical and Human Sciences, Târgu-Mureş. This topic has not been treated separately so far, it has only been discussed implicitly, included in other topics. But we believe that future teachers should have a more thorough theoretical and practical training in terms of what incorporating culture into language teaching implies. For this purpose, we are going to examine and discuss some of the recommendations and principles stated in the specialized literature regarding culture in foreign language teaching and reflect on what the ideal content of a course related to the teaching of this skill should be.
Jack C Richards
Full Text Available One quality among the many that characterize effective teachers is the ability to bring a creative disposition to teaching. In second language teaching, creativity has also been linked to levels of attainment in language learning. Many of the language tasks favored by contemporary language teaching methods are believed to release creativity in learners – particularly those involving studentcentred, interaction-based, and open-ended elements. Drawing on teacher narratives and conversations with teachers, the notion of creativity in language teaching is explored from three different perspectives: 1. the qualities creative teachers possess. 2. how teachers apply creativity in their teaching. 3. how creativity can be supported in the school. Examples illustrate how creative teachers’ conceptualize their approaches to teaching.
This book presents the Natural Constraint Language (NCL) language, a description language in conventional mathematical logic for modeling and solving constraint satisfaction problems. It uses illustrations and tutorials to detail NCL and its applications.
Locke, John L; Bogin, Barry
It has long been claimed that Homo sapiens is the only species that has language, but only recently has it been recognized that humans also have an unusual pattern of growth and development. Social mammals have two stages of pre-adult development: infancy and juvenility. Humans have two additional prolonged and pronounced life history stages: childhood, an interval of four years extending between infancy and the juvenile period that follows, and adolescence, a stage of about eight years that stretches from juvenility to adulthood. We begin by reviewing the primary biological and linguistic changes occurring in each of the four pre-adult ontogenetic stages in human life history. Then we attempt to trace the evolution of childhood and juvenility in our hominin ancestors. We propose that several different forms of selection applied in infancy and childhood; and that, in adolescence, elaborated vocal behaviors played a role in courtship and intrasexual competition, enhancing fitness and ultimately integrating performative and pragmatic skills with linguistic knowledge in a broad faculty of language. A theoretical consequence of our proposal is that fossil evidence of the uniquely human stages may be used, with other findings, to date the emergence of language. If important aspects of language cannot appear until sexual maturity, as we propose, then a second consequence is that the development of language requires the whole of modern human ontogeny. Our life history model thus offers new ways of investigating, and thinking about, the evolution, development, and ultimately the nature of human language.
Marc D Hauser
Full Text Available Understanding the evolution of language requires evidence regarding origins and processes that led to change. In the last 40 years, there has been an explosion of research on this problem as well as a sense that considerable progress has been made. We argue instead that the richness of ideas is accompanied by a poverty of evidence, with essentially no explanation of how and why our linguistic computations and representations evolved. We show that, to date, 1 studies of nonhuman animals provide virtually no relevant parallels to human linguistic communication, and none to the underlying biological capacity; 2 the fossil and archaeological evidence does not inform our understanding of the computations and representations of our earliest ancestors, leaving details of origins and selective pressure unresolved; 3 our understanding of the genetics of language is so impoverished that there is little hope of connecting genes to linguistic processes any time soon; 4 all modeling attempts have made unfounded assumptions, and have provided no empirical tests, thus leaving any insights into language’s origins unverifiable. Based on the current state of evidence, we submit that the most fundamental questions about the origins and evolution of our linguistic capacity remain as mysterious as ever, with considerable uncertainty about the discovery of either relevant or conclusive evidence that can adjudicate among the many open hypotheses. We conclude by presenting some suggestions about possible paths forward.
Metzner, John R
ACM Monograph Series: Decision Table Languages and Systems focuses on linguistic examination of decision tables and survey of the features of existing decision table languages and systems. The book first offers information on semiotics, programming language features, and generalization. Discussions focus on semantic broadening, outer language enrichments, generalization of syntax, limitations, implementation improvements, syntactic and semantic features, decision table syntax, semantics of decision table languages, and decision table programming languages. The text then elaborates on design im
The national core curriculum for basic education in Finland emphasizes language aware education (kielitietoisuus) with each adult a language model and language teacher (FNBE, 2014: 28). This approach recognises pupil diversity and the need to address language as a key tool in teaching and learning as well as for societal integration. In language aware education, the responsibility for pupils’ language development is shared across the school community. Discussions around this issue recognise t...
In spite of growing numbers in high schools and colleges, US-resident adolescent bilingual learners, sometimes termed "English as a second language" (ESL) or "Generation 1.5," are not succeeding academically in proportion to their monolingual English-speaking peers. This achievement gap is evident in their writing as they enter…
Full Text Available This paper intends to analyze the potential of smart cities from a linguistic perspective, with particular attention towards aspects such as second language acquisition (SLA, social inclusion and innovation, but also positive influences on sectors such as tourism and commerce. After an introduction of the theoretical foundations, the possible developing scenarios will be taken into consideration and analyzed more in detail.
Reich, Hans H.; Pornbacher, Ulrike
Policy and planning concerning the minority languages of immigrants are discussed, focusing on three countries receiving many immigrants: England, France, and Germany. First, similarities and differences in the immigration histories of the three countries, and in their policies concerning education of immigrants, are examined. Then policy…
Arkkila, Eva; Smolander, Sini; Laasonen, Marja
Specific language impairment is one of the most common developmental disturbances in childhood. With the increase of the foreign language population group an increasing number of children assimilating several languages and causing concern in language development attend clinical examinations. Knowledge of factors underlying the specific language impairment and the specific impairment in general, special features of language development of those learning several languages, as well as the assessment and support of the linguistic skills of a multilingual child is essential. The risk of long-term problems and marginalization is high for children having specific language impairment.
de Villiers, Peter A; de Villiers, Jill G
This review addresses questions of what should be assessed in language acquisition, and how to do it. The design of a language assessment is crucially connected to its purpose, whether for diagnosis, development of an intervention plan, or for research. Precise profiles of language strengths and weaknesses are required for clear definitions of the phenotypes of particular language and neurodevelopmental disorders. The benefits and costs of formal tests versus language sampling assessments are reviewed. Content validity, theoretically and empirically grounded in child language acquisition, is claimed to be centrally important for appropriate assessment. Without this grounding, links between phenomena can be missed, and interpretations of underlying difficulties can be compromised. Sensitivity and specificity of assessment instruments are often assessed using a gold standard of existing tests and diagnostic practices, but problems arise if that standard is biased against particular groups or dialects. The paper addresses the issues raised by the goal of unbiased assessment of children from diverse linguistic and cultural backgrounds, especially speakers of non-mainstream dialects or bilingual children. A variety of new approaches are discussed for language assessment, including dynamic assessment, experimental tools such as intermodal preferential looking, and training studies that assess generalization. Stress is placed on the need for measures of the process of acquisition rather than just levels of achievement. Copyright © 2010 John Wiley & Sons, Ltd. For further resources related to this article, please visit the WIREs website. Copyright © 2010 John Wiley & Sons, Ltd.
Mar 3, 2005 ... Journal of Biosciences. Current Issue : Vol. 43, Issue 1 · Current Issue Volume 43 | Issue 1. March 2018. Home · Volumes & Issues · Special Issues · Forthcoming Articles · Gallery of Cover Art · Search · Online submission at eBiosciences · Editorial Board · Information for Authors · Subscription ...
probabilities can vary due to factors such as individual and environmental differences in real-world systems. When it comes to the randomness of variable re- sets...approximation techniques. The over-approximation methods enrich the behavior of the system by releasing con- straints. They establish a relationship between...framework is implemented in Python . The simulator described in Chapter 7.3 is implemented in Java . We use PRISM  as our statistical model
Youdell, Deborah; Harwood, Valerie; Lindley, Martin R.
There are well documented concerns with the imposition of high stakes testing into the fabric of school education, and there is now an increasing focus on how such tests impact children's "well-being." This can be witnessed in reports in the popular news media, where discussion of these impacts frequently refer to "stress" and…
Evans, Nicholas; Levinson, Stephen C
Talk of linguistic universals has given cognitive scientists the impression that languages are all built to a common pattern. In fact, there are vanishingly few universals of language in the direct sense that all languages exhibit them. Instead, diversity can be found at almost every level of linguistic organization. This fundamentally changes the object of enquiry from a cognitive science perspective. This target article summarizes decades of cross-linguistic work by typologists and descriptive linguists, showing just how few and unprofound the universal characteristics of language are, once we honestly confront the diversity offered to us by the world's 6,000 to 8,000 languages. After surveying the various uses of "universal," we illustrate the ways languages vary radically in sound, meaning, and syntactic organization, and then we examine in more detail the core grammatical machinery of recursion, constituency, and grammatical relations. Although there are significant recurrent patterns in organization, these are better explained as stable engineering solutions satisfying multiple design constraints, reflecting both cultural-historical factors and the constraints of human cognition. Linguistic diversity then becomes the crucial datum for cognitive science: we are the only species with a communication system that is fundamentally variable at all levels. Recognizing the true extent of structural diversity in human language opens up exciting new research directions for cognitive scientists, offering thousands of different natural experiments given by different languages, with new opportunities for dialogue with biological paradigms concerned with change and diversity, and confronting us with the extraordinary plasticity of the highest human skills.
Having taught and carried out research in LSP and business communication for many years, I have come across, again and again, the problems arising from the inferior status of language in the business environment. Being convinced that it does not have to be so, instead of going on trying to convin...... non-linguistically trained colleagues of the importance of language via the usual arguments, I suggest that we let them experience the problems arising from the non-recognition of the importance of language via a Web communication crash course, inspired by a course taught to BA students...
Memory, Mind and Language celebrates the 30th anniversary of the The Nordic Association of Linguists (NAL) and the main contribution is the history of those first 30 years. The book is also an overview of trends and basic problems in linguistics in the first decennium of the 21st century. It takes...... up a number of topics in the field, among them the question of synchrony vs. diachrony in the language sciences, and issues of how to investigate the relationship between language, brain and mind. The book proposes some preliminary solutions to that problem, and, most significantly, it touches...
The LK scripting language is a simple and fast computer programming language designed for easy integration with existing software to enable automation of tasks. The LK language is used by NREL’s System Advisor Model (SAM), the SAM Software Development Kit (SDK), and SolTrace products. LK is easy extensible and adaptable to new software due to its small footprint and is designed to be statically linked into other software. It is written in standard C++, is cross-platform (Windows, Linux, and OSX), and includes optional portions that enable direct integration with graphical user interfaces written in the open source C++ wxWidgets Version 3.0+ toolkit.
Oga-Baldwin, W. L. Quint; Nakata, Yoshiyuki
The use and appropriate amount of students' own language (OL) in foreign language classes remains a subject of debate. While exclusive new language (NL) use may not necessarily always benefit all learners, especially young language learners (YLLs), overuse of the students' OL may not provide the same range of communicative experiences as greater…
Rezaei, Saeed; Khatib, Mohammad; Baleghizadeh, Sasan
The present study is a nationwide survey of language identity among English language learners in Iran. The participants who completed the survey in this research included 1851 English language learners from different parts of the country who belonged to different genders, age groups and English language proficiency levels. The main instrument was…
SMS language is English language slang, used as a means of mobile phone text messaging. This practice may impact on the written language skills of learners at school. The main aim of this study was to determine the perspectives of Grade 8 and 9 English (as Home Language) educators in Gauteng regarding the ...
The author spent four years embedded in a multilingual kindergarten classroom in which children spoke six different languages and several more years observing multilingual Head Start classrooms. She shares numerous examples of young dual language learners actively figuring out the way written language works in their first and second languages.…
Ball, Martin; Crystal, David; Fletcher, Paul
This collection is a resource book for those working with language disordered clients in a range of languages. It collects together versions of the well-known Language Assessment Remediation Screening Procedure (LARSP) prepared for different languages. Starting with the original version for English, the book then presents versions in more than a…
Language is the most important information and communication characteristics of all the human beings. Language is power as well as a great instrument for cultural preservation. The world community is made up of many languages and each of these languages is being used to identify one speech community or race.
The present study explores Korean students' demonstration of language awareness through their engagement in language play. Grounded in the understanding of the relationship between language play and an "engagement with language" (EWL) perspective, this ethnographic and discourse analytic study investigates how Korean students aged 11-15…
This paper discusses the relationship between entrenched beliefs about language ("language ideologies") and the linguistic system, and considers how conflicts between propositional and procedural knowledge about language have an effect upon the way in which language is regulated within society. It examines the epistemological foundations for…
Gomez-Laich, Maria Pia
Pragmatic competence is an indispensable aspect of language ability in order for second and foreign language (L2/FL) learners to understand and be understood in their interactions with both native and nonnative speakers of the target language. Without a proper understanding of the pragmatic rules in the target language, learners may run the risk…
language is the key note of culture because without it, culture does not exist. It is the medium of language ... instance is the language of the Jews (Hebrew), which has been the secret and root of the existence of the ..... intelligence data across the globe have exploited the apparent exclusiveness of the. Hebrew language.
Wong, Lung-Hsiang; Chai, Ching Sing; Aw, Guat Poh
This conceptual paper describes a language learning model that applies social media to foster contextualized and connected language learning in communities. The model emphasizes weaving together different forms of language learning activities that take place in different learning contexts to achieve seamless language learning. it promotes social…
Its results are discussed within the contours of five categories: learners' motivations for learning language; their ideas about language learning aptitude; their opinions of the difficulty of learning English; their second language learning and communication strategies; and, finally, their views on the nature of language learning.
Italian Sign Language (LIS) is the name of the language used by the Italian Deaf community. The acronym LIS derives from Lingua italiana dei segni ("Italian language of signs"), although nowadays Italians refers to LIS as Lingua dei segni italiana, reflecting the more appropriate phrasing "Italian sign language." Historically,…
Sánchez, María Teresa; García, Ofelia; Solorza, Cristian
This article addresses language allocation policies in what is increasingly called "Dual Language Education" (DLE) in the U.S., offering a challenge to the strict language separation policies in those programs and a proposal for flexibility that transforms them into "Dual Language Bilingual Education" (DLBE). The article offers…
Solomon, Jeff; Rhodes, Nancy
A project to identify alternative strategies for assessing the academic language of English language learners is reported. First, literature on the concept of academic language is reviewed, and then findings from classroom research are used to propose an alternative conceptualization of academic language, one which focuses on the role of stylistic…
Rivers, William P.; Brecht, Richard D.
In honor of the 50th Anniversary of "Foreign Language Annals," and recognizing the seminal role this journal has in informing the language education profession about policies and programs, we sketch a future for advocacy for language education in the United States. Drawing on the Languages for All initiative and the work of the…
This handbook outlines learning strategies in language arts for children in kindergarten to third grade learning English as a second language (ESL). They are designed for the Whole Language or Natural Approach. Although reading and writing are the key language components emphasized, listening, speaking, drama, and visual arts activities have been…
This fourth chapter presents: cell structure and metabolism; radiation interaction with biological tissues; steps of the production of biological effect of radiation; radiosensitivity of tissues; classification of biological effects; reversibility, transmissivity and influence factors; pre-natal biological effects; biological effects in therapy and syndrome of acute irradiation
Formulaic language studies remain less well recognized in language disorders. Profiles of differential formulaic language abilities in neurological disease have implications for cerebral models of language and for clinical evaluation and treatment of neurogenic language disorders.
Full Text Available A distinction is made between attitudes and specifically language attitudes. The process of acculturation is dealt with and its influence upon the motivation of ESL learners. Integrational and instmmental motivation are defined. Teachers' language attitudes, the dangers of prejudice and stereotyping are discussed. ,Attitude changes are analysed as well as the teacher's role in effecting them. 'n Onderskeid word getref tussen algemene houdings en houdings ten opsigte van taal. Die proses van akkulturasie word behandel, asook die invloed daarvan op die motivering van Engels Tweede Taal-leerders. Die skrywer onderskei verder tussen integrerende en instmmentale motivering. Die onderwysers se houding teenoor die taal word ook bespreek, asook die gevare van bevooroordeeldheid en stereotipering. Veranderinge in houdings word ontleed, en vera! die rol wat die onderwyser speel om die veranderinge teweeg te bring.
Full Text Available AbstractThis paper addresses two questions: 1 what are the impacts of language proficiency on the earnings of Canadian adult immigrants; 2 what are the current policy responses. Using a five-level scale of English/French language use, our analysis of Public Use Microdata Filefor the 2001 census confirms the positive association between proficiency in Canada’s charter language(s and immigrant earnings. Compared to permanent residents who are highly proficient in English and/or French, those with lower levels of proficiency have lower weekly earnings. Quantile regressions reveal that the relative advantage of English/French language proficiency is higher for those in the top quarter of the earnings distribution; conversely, greaterpenalties exist for immigrants with low levels of language proficiency at the upper end of the earnings distribution. The likely impacts of federal policies on increasing English/French language proficiency of immigrant workers are discussed, focusing on two federal government initiatives for language training and two recent immigration policy changes. RésuméCet article adresse deux questions : 1 quels sont les effets de la maîtrise de la langue sur les gains des immigrants canadiens adultes, et 2 quelles sont les politiques correctives actuelles. En nous servant d’une échelle à cinq niveaux d’usage des langues française et anglaise, notre analyse des microdonnées à grande diffusion du recensement de 2001 confirme la relation positive entre la maîtrise d’une ou des deux langues officielles du Canada et les gains des immigrants. Comparés aux résidents permanents qui ont une excellente maîtrise du français et/ou de l’anglais, les immigrants qui ont des bons niveaux de maîtrise de ces langues gagnentdes salaires hebdomadaires plus réduits. Les régressions par quantiles révèlent que la maîtrise du français et/ou de l’anglais apporte un plus grand avantage pour ceux dans le quart supérieur de
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Jurgens, Hartmut; And Others
The production and application of images based on fractal geometry are described. Discussed are fractal language groups, fractal image coding, and fractal dialects. Implications for these applications of geometry to mathematics education are suggested. (CW)
VIA Team Mission Statement: To develop a near real time, two way, mobile, lightweight, robust and low cost multi-lingual language translation device that can be operated with minimal training in a hands free manner...
Stăncuţa Ramona DIMA-LAZA
Full Text Available Intercultural language and communication skills vary across culture. Blunders are the result of an improper understanding of other nation’s language, non-verbal communication or customs and traditions. The present paper represents an incursion into the world of inaccurate translations and misinterpretations caused by a lack of ability to overcome cultural and language barriers. It also provides solutions for such problems, exemplifying with relevant situations. It informs the reader about writing principles and style, examining the outcome of conveying an inaccurate message. People write, deliver speeches or communicate for different purposes: to learn something, to entertain or to make money. Whether it is about one reason or another, the basic idea is to comply with certain language codes in order to avoid cultural conflicts.
The goal of this work is to explore techniques for making today's software, which is largely written in type-unsafe, low-level languages such as C, as reliable and trustworthy as code written in type...
German A. Ivanov
Full Text Available In this paper the problem of interdependence between power and language is viewed. The authors point out that the problem may be investigated in two aspects: from the point of view of a conscious use of language as a political instrument and from the point of view of an unconscious dependence of an individual on language and ideology. In this context, the authors investigate the ideas expressed by Louis Althusser and Michel Pźcheux. The theory of Ideological State Apparatuses by Althusser is represented here as one of possible conceptual bases for defining gender distribution of power. In this paper the specificity of the Pźcheux’s discourse analysis is revealed: discourse is viewed by Pźcheux as a sphere of intersection of language and extra-linguistic restrictions created by ideology.
National Aeronautics and Space Administration — The MPC (Model Process Control) language enables the capture, communication and preservation of a simulation instance, with sufficient detail that it can be...
Bryanne, Ulla; Bruntt, Karen Scheel Lassen
Handbook for Language Detectives gives a thorough presentation of English grammar and discusses how to teach grammar. The book unveils to the readers, who will be working as grammar detectives, the fascinating world of language. It does not only deal with "traditional grammar" but also discusses...... what different grammatical structures mean (semantics) and how they influence the level of style (pragmatics). Grammar should not be taught as a separate discipline; it can and should be integrated in communicative language teaching. The book gives you innovative and valuable ideas of how this can...... be done. The book serves a double purpose: - English grammar and language usage at bachelor level from a functional linguistic point of view. - How to teach English grammar within a communicative approach. The book is mainly intended for Danish student teachers of English, but anyone else interested...
This review begins with a definition of biological evolution and a description of its general principles. This is followed by a presentation of the biological basis of culture, specifically the concept of social selection. Further, conditions for cultural evolution are proposed, including a suggestion for language being the cultural replicator corresponding to the concept of the gene in biological evolution. Principles of cultural evolution are put forward and compared to the principles of biological evolution. Special emphasis is laid on the principle of selection in cultural evolution, including presentation of the concept of cultural fitness. The importance of language as a necessary condition for cultural evolution is stressed. Subsequently, prime differences between biological and cultural evolution are presented, followed by a discussion on interaction of our genome and our culture. The review aims at contributing to the present discussion concerning the modern development of the general theory of evolution, for example by giving a tentative formulation of the necessary and sufficient conditions for cultural evolution, and proposing that human creativity and mind reading or theory of mind are motors specific for it. The paper ends with the notion of the still ongoing coevolution of genes and culture.
International audience; This article investigates the language practices and language policies of an Indian migrant family in their daily life in Finland. The purpose of this paper is to consider the potential of an empirical case study on migration to understand the interrelationship between macro and micro analyses of language policies and practices. Though the migrant language instruction is encouraged and executed under the national language policy in Finland, the second generation of the...
The present focus on embodiment in cognitive science undervalues concepts such as convention/norm, representation and consciousness. I argue that these concepts constitute essential properties of language, and this makes it problematic for “embodiment theories” to account for human language and cognition. These difficulties are illustrated by examining a particular, highly influential approach to embodied cognition, that of Lakoff and Johnson (1999), and exposing the problematic character of ...
Hartling, Anna Sofie; Nørreby, Thomas Rørbeck; Skovse, Astrid Ravn
Language works! – and with this initiative and this journal we want to give the opportunity to many more students to present their linguistic research to each other, to the scientific community and to all interested.......Language works! – and with this initiative and this journal we want to give the opportunity to many more students to present their linguistic research to each other, to the scientific community and to all interested....
Liliegren, Ann-Sofie; Peulicke Borggreen, Babette; Slott Nielsen, Christoffer; Granados Fernandez, Esther; Bellido Ponferrada, Isabel; Løwenstein Holmen, Ida; Wakimura, Yurie
This paper investigates how revealing it is to talk about English as the new Latin. Parallels between the two languages are drawn by using different approaches from the linguistic, philosophical and communicational field. This is put into context by a historical background of Latin, as well as the status of English today. Throughout the report, the focal point is Francis Bacon’s statement, ‘knowledge is power’, and the complex relation between knowledge, power and language. ...
Language Analysis Tool Development Tools in other languages. Given the multicultural nature of many working groups within the Army and within...Linguistic analysis of workplace computer-mediated communication. Proceedings of Computer Supported Cooperative Work 2010, ACM Press. Seider, B...Science, 17, 660–664. *Tausczik, Y. R. (2009) Linguistic analysis of workplace computer-mediated communication (Unpublished master’s thesis.) The
Shusman, Daniel J.; Morgan, Mary M.; Zielstorff, Rita; Barnett, G. Octo
The Medical Query Language (MQL) is an English-like query language with which a user with little or no training in programming or computer science can formulate and satisfy inquiries on data contained in his/her Standard MUMPS database. To date, major applications of MQL have been in the areas of quality assurance, medical research, and practice administration at sites using the COmputer STored Ambulatory Record (COSTAR) database system.
hundreds guish one language from another. The reader is referred of input languages would need to be supported , the cost of to the linguistics literature...eventually obtained bet- 108 TRAINING FRENCH GERMAN ITRAIING FRENCH M- ALGORITHM - __ GERMAN NHSPANISH TRAINING SPEECH SET OF MODELS: UTTERANCES ONE MODEL...i.e. vowels ) for each speech utterance are located malized to be insensitive to overall amplitude, pitch and automatically. Next, feature vectors