Potentials and limitations of hazard indices for the determination of risk potentials of disposed toxic wastes

International Nuclear Information System (INIS)

Kirchner, Gerald

1989-01-01

Hazard indices are often used for the determination of risk potentials arising from the geological disposal of toxic wastes. They are based on simplified models for the calculation of potential health effects caused by the wastes. The attractiveness of hazard indices lies in their simplicity which nevertheless results in reliable data on necessary isolation times and the most toxic nuclides of a waste. They also make possible comparisons of the potential risks of different wastes. After a discussion of the processes that control the behavior of toxic wastes in the environment after a failure of the geological barriers, a new hazard index is presented. Originally developed for nuclear wastes, it is the first which involves the joint consideration of the composition of a waste, the probability for transport of waste nuclides to man, their toxicity, and the time-dependent changes of the risk potentials which are caused by radioactive buildup and decay processes after the waste has entered the biosphere. The new hazard index makes possible the calculation of risk potentials at a given time of release and time period of concern thereafter. Sample calculations for different nuclear wastes show the importance of the model improvements on resulting time-dependent risk potentials. Applicability of the new hazard index to non-nuclear wastes is described. Potentials and limitations of comparative risk assessments using hazard indices are discussed. (author)

Potential health hazard of nuclear fuel waste and uranium ore

International Nuclear Information System (INIS)

Mehta, K.; Sherman, G.R.; King, S.G.

1991-06-01

The variation of the radioactivity of nuclear fuel waste (used fuel and fuel reprocessing waste) with time, and the potential health hazard (or inherent radiotoxicity) resulting from its ingestion are estimated for CANDU (Canada Deuterium Uranium) natural-uranium reactors. Four groups of radionuclides in the nuclear fuel waste are considered: actinides, fission products, activation products of zircaloy, and activation products of fuel impurities. Contributions from each of these groups to the radioactivity and to the potential health hazard are compared and discussed. The potential health hazard resulting from used fuel is then compared with that of uranium ore, mine tailings and refined uranium (fresh fuel) on the basis of equivalent amounts of uranium. The computer code HAZARD, specifically developed for these computations, is described

Hazard identification and risk assessment for biologics targeting the immune system.

Science.gov (United States)

Weir, Andrea B

2008-01-01

Biologic pharmaceuticals include a variety of products, such as monoclonal antibodies, fusion proteins and cytokines. Products in those classes include immunomodulatory biologics, which are intended to enhance or diminish the activity of the immune system. Immunomodulatory biologics have been approved by the U.S. FDA for a variety of indications, including cancer and inflammatory conditions. Prior to gaining approval for marketing, sponsoring companies for all types of products must demonstrate a product's safety in toxicology studies conducted in animals and show safety and efficacy in clinical trials conducted in patients. The overall goal of toxicology studies, which applies to immunomodulatory and other product types, is to identify the hazards that products pose to humans. Because biologics are generally highly selective for specific targets (receptors/epitopes), conducting toxicology studies in animal models with the target is essential. Such animals are referred to as pharmacologically relevant. Endpoints routinely included in toxicology studies, such as hematology, organ weight and histopathology, can be used to assess the effect of a product on the structure of the immune system. Additionally, specialized endpoints, such as immunophenotyping and immune function tests, can be used to define effects of immunomodulatory products on the immune system. Following hazard identification, risks posed to patients are assessed and managed. Risks can be managed through clinical trial design and risk communication, a practice that applies to immunomodulatory and other product types. Examples of risk management in clinical trial design include establishing a safe starting dose, defining the appropriate patient population and establishing appropriate patient monitoring. Risk communication starts during clinical trials and continues after product approval. A combination of hazard identification, risk assessment and risk management allows for drug development to proceed

Engineered Nanomaterials, Sexy New Technology and Potential Hazards

International Nuclear Information System (INIS)

Beaulieu, R.A.

2009-01-01

Engineered nanomaterials enhance exciting new applications that can greatly benefit society in areas of cancer treatments, solar energy, energy storage, and water purification. While nanotechnology shows incredible promise in these and other areas by exploiting nanomaterials unique properties, these same properties can potentially cause adverse health effects to workers who may be exposed during work. Dispersed nanoparticles in air can cause adverse health effects to animals not merely due to their chemical properties but due to their size, structure, shape, surface chemistry, solubility, carcinogenicity, reproductive toxicity, mutagenicity, dermal toxicity, and parent material toxicity. Nanoparticles have a greater likelihood of lung deposition and blood absorption than larger particles due to their size. Nanomaterials can also pose physical hazards due to their unusually high reactivity, which makes them useful as catalysts, but has the potential to cause fires and explosions. Characterization of the hazards (and potential for exposures) associated with nanomaterial development and incorporation in other products is an essential step in the development of nanotechnologies. Developing controls for these hazards are equally important. Engineered controls should be integrated into nanomaterial manufacturing process design according to 10CFR851, DOE Policy 456.1, and DOE Notice 456.1 as safety-related hardware or administrative controls for worker safety. Nanomaterial hazards in a nuclear facility must also meet control requirements per DOE standards 3009, 1189, and 1186. Integration of safe designs into manufacturing processes for new applications concurrent with the developing technology is essential for worker safety. This paper presents a discussion of nanotechnology, nanomaterial properties/hazards and controls

Implementation of health and safety management system to reduce hazardous potential in PT.XYZ Indonesia

Science.gov (United States)

Widodo, L.; Adianto; Sartika, D. I.

2017-12-01

PT. XYZ is a large automotive manufacturing company that manufacture, assemble as well as a car exporter. The other products are spare parts, jig and dies. PT. XYZ has long been implementing the Occupational Safety and Health Management System (OSHMS) to reduce the potential hazards that cause work accidents. However, this does not mean that OSHMS that has been implemented does not need to be upgraded and improved. This is due to the potential danger caused by work is quite high. This research was conducted in Sunter 2 Plant where its production activities have a high level of potential hazard. Based on Hazard Identification risk assessment, Risk Assessment, and Risk Control (HIRARC) found 10 potential hazards in Plant Stamping Production, consisting of 4 very high risk potential hazards (E), 5 high risk potential hazards (H), and 1 moderate risk potential hazard (M). While in Plant Casting Production found 22 potential hazards findings consist of 7 very high risk potential hazards (E), 12 high risk potential hazards (H), and 3 medium risk potential hazards (M). Based on the result of Fault Tree Analysis (FTA), the main priority is the high risk potential hazards (H) and very high risk potential hazards (E). The proposed improvement are to make the visual display of the importance of always using the correct Personal Protective Equipment (PPE), establishing good working procedures, conducting OSH training for workers on a regular basis, and continuing to conduct safety campaigns.

Potential hazards and risks associated with the aquaculture industry ...

African Journals Online (AJOL)

Aquaculture, the farming of aquatic organisms, is fraught with potential hazards and risks which are categorized into occupational, environmental, food safety and public health. This paper reviewed major hazards and risks associated with the aquaculture industry and proffered strategies for their management and control.

Organization A Comprehensive System Of Insurance Coverage In The Potential Chemical And Biological Contamination Zone In Regions

Directory of Open Access Journals (Sweden)

Nina Vladimirovna Zaytseva

2014-12-01

Full Text Available The article provides a scientific rationale for an integrated approach to the provision of insurance coverage in the potential chemical and biological contamination zone. The following modern forms of chemical safety in the Russian Federation were considered: state reserve’s system, target program financing, state social insurance. The separate issue tackles the obligatory civil liability insurance for owners of dangerous objects. For improvement of the existing insurance protection system against emergency situations, risks were analyzed (shared on exogenous and endogenous. Among the exogenous risks including natural and climatic conditions of a region, its geographical arrangement, economic specialization, the seismic and terrorist risks were chosen and approaches to its solution were suggested. In endogenous risks’ group, the special focus is on wear and tear and obsolescence of hazardous chemical and biological object’s fixed assets. In case of high risk of an incident, it is suggested to increase in extent of insurance protection through self-insurance, a mutual insurance in the form of the organization of societies of a mutual insurance or the self-regulating organizations, and also development of voluntary insurance of a civil liability, both the owner of hazardous object, and regions of the Russian Federation and municipalities. The model of insurance coverage in the potential chemical and biological contamination zone is based on a differentiated approach to the danger level of the area. A matrix of adequate forms and types of insurance (required for insurance coverage of the population in the potential chemical and biological contamination zone was constructed. Proposed health risk management toolkit in the potential chemical and biological contamination zone will allow to use financial resources for chemical and biological safety in the regions more efficiently.

PRELIMINARY CONSIDERATIONS ON SUSHI AS POTENTIALLY HAZARDOUS FOOD

OpenAIRE

G. Liuzzo; P. Bonilauri; R. Leonelli; A. Serraino; S. Bentley

2011-01-01

The Authors studied physicochemical properties (pH and Aw) of samples of Nigiri sushi and their ingredients along their shelf life, integrating those results with a predictive microbiological model, in order to determine or to rule out the growth of Listeria monocytogenes above the thresholds set by Reg.(EU) 2073/2005. Results point towards substantial containment of the target biological hazard, even though the prevention of thermal abuse is a keypoint in increasing safety.

NATO Advanced Research Workshop, 19-22 May 1997: Rapid Method for Monitoring the Environment for Biological Hazards

National Research Council Canada - National Science Library

1997-01-01

The NATO Advanced Research Workshop met for the purpose of bringing to light rapid methods for monitoring the environment for biological hazards such as biological warfare agents, naturally occurring...

Reducing the risk of potential hazard in tourist activities of Mount Bromo

Science.gov (United States)

Meilani, R.; Muthiah, J.; Muntasib, E. K. S. H.

2018-05-01

Mount Bromo has been crowned as one of the most beautiful mountains in the world, having a particular landscape uniqueness. Not only volcano, Bromo also has savanna, sea of sands, and culture of Tengger tribe. Its panoramic landscape has attracted a large number of tourists, both domestic and foreign, despites the threat of eruption. To ensure tourists safety and satisfaction, the potentials hazard, both from eruption and other features should be managed carefully. The study objective was to identify and map hazard potentials and identify the existing hazard management. It was carried out in Mei – June 2017. Lava, tephra, eruption cloud, ash, earthquake, land sliding, extreme weather, slope, transportation modes (jeep, motorcycle, and horse), human, and land fire were found as potential hazards in Mount Bromo. Five locations had been identified as hazard area in the tourism areas, i.e. savanna, sea of sand, Bromo caldera and Pananjakan I trail and viewing point. Early warning system should be developed as part of hazard management in the area. Capacity building of local stakeholders and visitors would be needed to reduce risk of the hazard.

Self-Medication: potential risks and hazards among pregnant ...

African Journals Online (AJOL)

Self-Medication: potential risks and hazards among pregnant women in Uyo, ... Reasons for using these substances range from protection from witches and ... shows that self-medication is common among pregnant women in our environment.

Potential hazard to secondary containment from HCDA-generated missiles and sodium fires

International Nuclear Information System (INIS)

Romander, C.M.

1979-02-01

The potential hazard of HCDA-generated missiles is analyzed, and the current status of the potential hazards of sodium fires is summarized. Simple analyses are performed to determine lower bounds on the HCDA energetics required to generate missiles that could reach the secondary containment structure of a 1000-MWe LMFBR. The potential missiles considered include the vessel head, components mounted on the head, and conrol rods

Potential for a hazardous geospheric response to projected future climate changes.

Science.gov (United States)

McGuire, B

2010-05-28

Periods of exceptional climate change in Earth history are associated with a dynamic response from the geosphere, involving enhanced levels of potentially hazardous geological and geomorphological activity. The response is expressed through the adjustment, modulation or triggering of a broad range of surface and crustal phenomena, including volcanic and seismic activity, submarine and subaerial landslides, tsunamis and landslide 'splash' waves, glacial outburst and rock-dam failure floods, debris flows and gas-hydrate destabilization. In relation to anthropogenic climate change, modelling studies and projection of current trends point towards increased risk in relation to a spectrum of geological and geomorphological hazards in a warmer world, while observations suggest that the ongoing rise in global average temperatures may already be eliciting a hazardous response from the geosphere. Here, the potential influences of anthropogenic warming are reviewed in relation to an array of geological and geomorphological hazards across a range of environmental settings. A programme of focused research is advocated in order to: (i) understand better those mechanisms by which contemporary climate change may drive hazardous geological and geomorphological activity; (ii) delineate those parts of the world that are most susceptible; and (iii) provide a more robust appreciation of potential impacts for society and infrastructure.

Microzonation of Seismic Hazard Potential in Taipei, Taiwan

Science.gov (United States)

Liu, K. S.; Lin, Y. P.

2017-12-01

The island of Taiwan lies at the boundary between the Philippine Sea plate and the Eurasia plate. Accordingly, the majority of seismic energy release near Taiwan originates from the two subduction zones. It is therefore not surprising that Taiwan has repeatedly been struck by large earthquakes such as 1986 Hualien earthquake, 1999 Chi Chi and 2002 Hualien earthquake. Microzonation of seismic hazard potential becomes necessary in Taipei City for the Central Geological Survey announced the Sanchiao active fault as Category II. In this study, a catalog of more than 2000 shallow earthquakes occurred from 1900 to 2015 with Mw magnitudes ranging from 5.0 to 8.2, and 11 disastrous earthquakes occurred from 1683-1899, as well as Sanchiao active fault in the vicinity are used to estimate the seismic hazard potential in Taipei City for seismic microzonation. Furthermore, the probabilities of seismic intensity exceeding CWB intensity 5, 6, 7 and MMI VI, VII, VIII in 10, 30, and 50-year periods in the above areas are also analyzed for the seismic microzonation. Finally, by comparing with the seismic zoning map of Taiwan in current building code that was revised after 921 earthquakes, Results of this study will show which areas with higher earthquake hazard potential in Taipei City. They provide a valuable database for the seismic design of critical facilities. It will help mitigate Taipei City earthquake disaster loss in the future, as well as provide critical information for emergency response plans.

Pesticides; resource recovery; hazardous substances and oil spill responses; waste disposal; biological effects

International Nuclear Information System (INIS)

Anon.

1991-01-01

In the category of pesticides this volume features close to sixty standard test method, practices, and guides for evaluating the properties and efficacy of pesticides and antimicrobial agents. Also covered are standards for hazardous substances, oil spell responses, waste disposal, and biological effects of these materials

Monitoring potential neurotoxic effects of hazardous waste disposal

OpenAIRE

Schaumburg, Herbert H.; Spencer, Peter S.; Arezzo, Joseph C.

1983-01-01

This report reviews neurotoxicological principles relevant to situations of hazardous waste disposal. Some of the diagnostic techniques currently used for field assessment of nervous system dysfunction are critically evaluated. These include nerve conduction velocity, evoked potentials, neuropsychological testing and use of the Optacon.

Regional Landslide Hazard Assessment Considering Potential Climate Change

Science.gov (United States)

Almeida, S.; Holcombe, E.; Pianosi, F.; Wagener, T.

2016-12-01

Landslides have many negative economic and societal impacts, including the potential for significant loss of life and damage to infrastructure. These risks are likely to be exacerbated in the future by a combination of climatic and socio-economic factors. Climate change, for example, is expected to increase the occurrence of rainfall-triggered landslides, because a warmer atmosphere tends to produce more high intensity rainfall events. Prediction of future changes in rainfall, however, is subject to high levels of uncertainty, making it challenging for decision-makers to identify the areas and populations that are most vulnerable to landslide hazards. In this study, we demonstrate how a physically-based model - the Combined Hydrology and Stability Model (CHASM) - can be used together with Global Sensitivity Analysis (GSA) to explore the underlying factors controlling the spatial distribution of landslide risks across a regional landscape, while also accounting for deep uncertainty around potential future rainfall triggers. We demonstrate how GSA can be used to analyse CHASM which in turn represents the spatial variability of hillslope characteristics in the study region, while accounting for other uncertainties. Results are presented in the form of landslide hazard maps, utilising high-resolution digital elevation datasets for a case study in St Lucia in the Caribbean. Our findings about spatial landslide hazard drivers have important implications for data collection approaches and for long-term decision-making about land management practices.

Dendritic cells and skin sensitization: Biological roles and uses in hazard identification

International Nuclear Information System (INIS)

Ryan, Cindy A.; Kimber, Ian; Basketter, David A.; Pallardy, Marc; Gildea, Lucy A.; Gerberick, G. Frank

2007-01-01

Recent advances have been made in our understanding of the roles played by cutaneous dendritic cells (DCs) in the induction of contact allergy. A number of associated changes in epidermal Langerhans cell phenotype and function required for effective skin sensitization are providing the foundations for the development of cellular assays (using DC and DC-like cells) for skin sensitization hazard identification. These alternative approaches to the identification and characterization of skin sensitizing chemicals were the focus of a Workshop entitled 'Dendritic Cells and Skin Sensitization: Biological Roles and Uses in Hazard Identification' that was given at the annual Society of Toxicology meeting held March 6-9, 2006 in San Diego, California. This paper reports information that was presented during the Workshop

Review of Pasteuria penetrans: Biology, Ecology, and Biological Control Potential.

Science.gov (United States)

Chen, Z X; Dickson, D W

1998-09-01

Pasteuria penetrans is a mycelial, endospore-forming, bacterial parasite that has shown great potential as a biological control agent of root-knot nematodes. Considerable progress has been made during the last 10 years in understanding its biology and importance as an agent capable of effectively suppressing root-knot nematodes in field soil. The objective of this review is to summarize the current knowledge of the biology, ecology, and biological control potential of P. penetrans and other Pasteuria members. Pasteuria spp. are distributed worldwide and have been reported from 323 nematode species belonging to 116 genera of free-living, predatory, plant-parasitic, and entomopathogenic nematodes. Artificial cultivation of P. penetrans has met with limited success; large-scale production of endospores depends on in vivo cultivation. Temperature affects endospore attachment, germination, pathogenesis, and completion of the life cycle in the nematode pseudocoelom. The biological control potential of Pasteuria spp. have been demonstrated on 20 crops; host nematodes include Belonolaimus longicaudatus, Heterodera spp., Meloidogyne spp., and Xiphinema diversicaudatum. Pasteuria penetrans plays an important role in some suppressive soils. The efficacy of the bacterium as a biological control agent has been examined. Approximately 100,000 endospores/g of soil provided immediate control of the peanut root-knot nematode, whereas 1,000 and 5,000 endospores/g of soil each amplified in the host nematode and became suppressive after 3 years.

Estimation of potential ecological hazard of solidificated waste disposal

International Nuclear Information System (INIS)

Krylova, N.V.

1980-01-01

The results of estimation of potential ecological hazard of vitrificated high-level radioactive wastes resulted from spent fuel reprocessing of LWR connected with a hypothetic storage damage being occurred in the 5O0-6000-year geologic period are presented. The total volume of the vitrificated wastes in the storage used for calculations is 12000 blocks. The data on vitrificated block radioactivity depending on the time after fuel regeneration, the density of the uniform distribution of vitrificated wastes over the earth surface, as well as the results of estimation of the man external and internal exposures due to radionuclide escape into the biosphere are given in tables. It is shown that the main hazard is caused by external irradiation. The inhalation dose may be significant for man, though the hazard due to radionuclide intake by ingestion is less

Potential hazard by toxic substances in foods. Environmental protection

Energy Technology Data Exchange (ETDEWEB)

Unterhalt, B

1974-01-01

This paper reviews various toxic substances found in foods. These toxic substances include not only natural occurring toxins but also bacterial food poisons, pesticide residues, heavy metals, and food additives. The potential hazard of each toxic substance is discussed. 74 references.

Uncertainties in biological responses that influence hazard and risk approaches to the regulation of endocrine active substances.

Science.gov (United States)

Parrott, Joanne L; Bjerregaard, Poul; Brugger, Kristin E; Gray, L Earl; Iguchi, Taisen; Kadlec, Sarah M; Weltje, Lennart; Wheeler, James R

2017-03-01

Endocrine-disrupting substances (EDS) may have certain biological effects including delayed effects, multigenerational effects, and may display nonmonotonic dose-response (NMDR) relationships that require careful consideration when determining environmental hazards. Endocrine disrupting substances can have specific and profound effects when exposure occurs during sensitive windows of the life cycle (development, reproduction). This creates the potential for delayed effects that manifest when exposure has ceased, possibly in a different life stage. This potential underscores the need for testing in appropriate (sensitive) life stages and full life cycle designs. Such tests are available in the Organisation for Economic Co-operation and Development (OECD) tool box and should be used to derive endpoints that can be considered protective of all life stages. Similarly, the potential for effects to be manifest in subsequent generations (multigenerational effects) has also been raised as a potential issue in the derivation of appropriate endpoints for EDS. However, multigenerational studies showing increasing sensitivity of successive generations are uncommon. Indeed this is reflected in the design of new higher tier tests to assess endocrine active substances (EAS) that move to extended one-generation designs and away from multi-generational studies. The occurrence of NMDRs is also considered a limiting factor for reliable risk assessment of EDS. Evidence to date indicates NMDRs are more prevalent in in vitro and mechanistic data, not often translating to adverse apical endpoints that would be used in risk assessment. A series of steps to evaluate NMDRs in the context of endocrine hazard and risk assessment procedures is presented. If careful consideration of delayed, multigenerational effects and NMDRs is made, it is feasible to assess environmental endocrine hazards and derive robust apical endpoints for risk assessment procedures ensuring a high level of environmental

Identification of potentially hazardous human gene products in GMO risk assessment.

Science.gov (United States)

Bergmans, Hans; Logie, Colin; Van Maanen, Kees; Hermsen, Harm; Meredyth, Michelle; Van Der Vlugt, Cécile

2008-01-01

Genetically modified organisms (GMOs), e.g. viral vectors, could threaten the environment if by their release they spread hazardous gene products. Even in contained use, to prevent adverse consequences, viral vectors carrying genes from mammals or humans should be especially scrutinized as to whether gene products that they synthesize could be hazardous in their new context. Examples of such potentially hazardous gene products (PHGPs) are: protein toxins, products of dominant alleles that have a role in hereditary diseases, gene products and sequences involved in genome rearrangements, gene products involved in immunomodulation or with an endocrine function, gene products involved in apoptosis, activated proto-oncogenes. For contained use of a GMO that carries a construct encoding a PHGP, the precautionary principle dictates that safety measures should be applied on a "worst case" basis, until the risks of the specific case have been assessed. The potential hazard of cloned genes can be estimated before empirical data on the actual GMO become available. Preliminary data may be used to focus hazard identification and risk assessment. Both predictive and empirical data may also help to identify what further information is needed to assess the risk of the GMO. A two-step approach, whereby a PHGP is evaluated for its conceptual dangers, then checked by data bank searches, is delineated here.

Butt rot defect and potential hazard in lodgepole pine on selected California recreational areas

Science.gov (United States)

Lee A. Paine

1966-01-01

Within the area sampled, potentially hazardous lodgepole pine were common on recreational sites. The incidence of decayed and mechanically weak trees was correlated with fire damage. Two-thirds of fire-scarred trees were decayed; one-third were rated potentially hazardous. Fire scars occurred roughly in proportion to level of plot recreational use.

Snow hazard potential evaluation along G217 highway in Tianshan mountains by using GIS and RS

Science.gov (United States)

Tao, Jianwei

2007-11-01

Snow hazard especially avalanche potential along G217 national highway in Tianshan Mountains using remote sensing and GIS is evaluated and compared with actual site records of avalanche in a test area. Most places of the actual avalanche accidents are consistent with the places with the high snow hazard potential. But there are several places of the avalanche were not in the high hazard potential areas. The reason for this difference is discussed.

Biological Potential in Serpentinizing Systems

Science.gov (United States)

Hoehler, Tori M.

2016-01-01

Generation of the microbial substrate hydrogen during serpentinization, the aqueous alteration of ultramafic rocks, has focused interest on the potential of serpentinizing systems to support biological communities or even the origin of life. However the process also generates considerable alkalinity, a challenge to life, and both pH and hydrogen concentrations vary widely across natural systems as a result of different host rock and fluid composition and differing physical and hydrogeologic conditions. Biological potential is expected to vary in concert. We examined the impact of such variability on the bioenergetics of an example metabolism, methanogenesis, using a cell-scale reactive transport model to compare rates of metabolic energy generation as a function of physicochemical environment. Potential rates vary over more than 5 orders of magnitude, including bioenergetically non-viable conditions, across the range of naturally occurring conditions. In parallel, we assayed rates of hydrogen metabolism in wells associated with the actively serpentinizing Coast Range Ophiolite, which includes conditions more alkaline and considerably less reducing than is typical of serpentinizing systems. Hydrogen metabolism is observed at pH approaching 12 but, consistent with the model predictions, biological methanogenesis is not observed.

EFSA Panel on Biological Hazards (BIOHAZ); Scientific Opinion on On-site treatment of pig carcasses

DEFF Research Database (Denmark)

Hald, Tine

EFSA’s Scientific Panel on Biological Hazards (BIOHAZ) was asked for a scientific opinion on an alternative method for processing Category (Cat) 2 Animal By-Products (ABP). The materials to be treated are placentas and fallen pigs; this implies that the animals died due to a disease, which in most...... of the animals’ death, the presence of more resistant hazards cannot be considered negligible. The sterilisation process defined in the current legislation is able to minimise the risks due to unidentified agents, such as Bacillus anthracis and TSE agents. The BIOHAZ Panel concluded that the process proposed...

Recommendations for sampling for prevention of hazards in civil defense. On analytics of chemical, biological and radioactive contaminations. Brief instruction for the CBRN (chemical, biological, radioactive, nuclear) sampling

International Nuclear Information System (INIS)

Bachmann, Udo; Biederbick, Walter; Derakshani, Nahid

2010-01-01

The recommendation for sampling for prevention of hazards in civil defense is describing the analytics of chemical, biological and radioactive contaminations and includes detail information on the sampling, protocol preparation and documentation procedures. The volume includes a separate brief instruction for the CBRN (chemical, biological, radioactive, nuclear) sampling.

Experimental investigation to evaluate the potential environmental hazards of photovoltaic panels.

Science.gov (United States)

Tammaro, Marco; Salluzzo, Antonio; Rimauro, Juri; Schiavo, Simona; Manzo, Sonia

2016-04-05

Recently the potential environmental hazard of photovoltaic modules together with their management as waste has attracted the attention of scientists. Particular concern is aroused by the several metals contained in photovoltaic panels whose potential release in the environment were scarcely investigated. Here, for the first time, the potential environmental hazard of panels produced in the last 30 years was investigated through the assessment of up to 18 releasable metals. Besides, the corresponding ecotoxicological effects were also evaluated. Experimental data were compared with the current European and Italian law limits for drinking water, discharge on soil and landfill inert disposal in order to understand the actual pollution load. Results showed that less than 3% of the samples respected all law limits and around 21% was not ecotoxic. By considering the technological evolutions in manufacturing, we have shown that during the years crystalline silicon panels have lower tendency to release hazardous metals with respect to thin film panels. In addition, a prediction of the amounts of lead, chromium, cadmium and nickel releasable from next photovoltaic waste was performed. The prevision up to 2050 showed high amounts of lead (30t) and cadmium (2.9t) releasable from crystalline and thin film panels respectively. Copyright © 2015 Elsevier B.V. All rights reserved.

EFSA Panel on Biological Hazards (BIOHAZ); Scientific Opinion on Composting and incineration of dead-on-farm pigs

DEFF Research Database (Denmark)

Hald, Tine

of biological hazards throughout the farm environment. Major deficiencies were noted in relation to the risk containment. Moreover, a formal HACCP plan was not provided, and some deficiencies were also noted in the identification of interdependent processes. Provided that the deficiencies identified......A method for on-farm processing of Category (Cat) 2 Animal By-Products (ABP) alternative to the ones already approved in the current legislation was assessed. The materials to be treated are placentas and dead-on-farm pigs. The proposed process consists of three sequential steps, i.e. composting......, storage of mature compost and incineration of mature compost in authorized plants. The applicant identified the main biological, physical and chemical hazards that could be present in the material to be treated and in the compost substrate. Since the compost is only intended for incineration the applicant...

Control Analysis of Hazards Potential in Crude Distiller Unit III PT. Pertamina (Persero) Refinery Unit III Plaju Tahun 2011

OpenAIRE

Matariani, Ade; Hasyim, Hamzah; Faisya, Achmad Fickry

2012-01-01

Background: Activities in CDU III are very risk to any hazards potential; because of that hazards potential is much needed in controlling the hazards potential to decrease the accidents and occupational diseases. The aim of this study was to analyze the controlling of hazards potential in CDU III PT. Pertamina (Persero) RU III Plaju in 2011. Method: This study was a qualitative study. The methods of data collection were using in-depth interview and observation. The total of informants in this...

Rotating biological contractor treatment of 2-nitrophenol and 2-chlorophenol containing hazardous wastes

International Nuclear Information System (INIS)

Tokuz, R.Y.

1990-01-01

Rotating Biological Contactors (RBCs) have a number of advantages over other biological treatment systems. For example, they can provide high treatment efficiencies of activated sludge systems with much lower energy inputs. Organic shock loads are handled well because large biomass is present. No bulking, foaming, or floating of sludge occurs and sludge has good settleability and dewaterability. Another advantage of RBC systems is the minimal labor requirement for operation and maintenance. Even though RBC systems have these advantages, their acceptance was slow mainly due to operational problems with the earlier units (such as shaft failures) and the lack of considerable design and operation data. A review of literature shows that there is only limited information available on the wastewater treatment with RBCs. Recently, there has been considerable contributions to the knowledge on RBC technology. However, information on the treatment of organic hazardous wastes using RBCs is still very limited. This paper reports that a considerable number of studies on the biological treatment of organic hazardous compounds was sponsored by U.S. Environmental Protection Agency (EPA). For example, an EPA sponsored study examined the effect of such compounds on the performance of activated sludge process. Bench-scale continuous-flow and batch units were used. Influent was settled municipal wastewater to which toxic compounds were added. In batch operations, 2-chlorophenol and pentachlorophenol caused an increase in the effluent Chemical Oxygen Demand (COD) at an influent concentration of 5 mg/L. No adverse effect of 2-nitrophenol on the batch system was reports. 2-Chlorophenol was one of the compounds that upset the performance of continuous-flow activated sludge units, yielding higher than normal levels of effluent suspended solids

Management and hazardous waste characterization in Central for Isotop and Radiation Application based on potential dangers

International Nuclear Information System (INIS)

Niken Hayudanti Anggarini; Megi Stefanus; Prihatiningsih

2014-01-01

Separating and storing hazardous waste have been done based on the physical, chemical, and based on potential dangers due to safety hazardous waste temporary storage warehouse. From the results of data collection in 2014 found that the most dominant hazardous waste is organic liquid waste which reaches 61 %, followed by inorganic liquid waste 33 % while organic solid waste and inorganic solid waste has a small portion. When viewed from potential danger, flammable liquid waste has the greatest volume percentage it is 47 % and is followed by a corrosive liquid waste 26 %, while the liquid waste that has not been identified is quite large, which is 9 %. From the highest hazard potential data, hazardous waste storage warehouse is required to have good air circulation and waste storage shelf protected from direct solar heat. Cooperation of lab workers and researchers are also indispensable in providing identification of each waste generated to facilitate the subsequent waste management. (author)

Hazardous air emissions potential from a wood-fired furnace

International Nuclear Information System (INIS)

Hubbard, A.J.

1995-01-01

During the first week of April, 1991 the Wisconsin Department of Natural Resources (WDNR) conducted a series of air emissions tests of a small industrial wood-fired boiler in northern Wisconsin. The boiler was firing a virgin hogged wood/wood waste fuel with a moisture content of about 35 percent. The pollutants measured were particulates, nitrogen oxides (NOx), carbon monoxide (GO), total hydrocarbons (THC), benzene, formaldehyde (CHOH), polycyclic organic matter (POM, e.g. Benzo (a) pyrene), aldehydes, and trace metals (As, Ba, Cu, Pb, Mn, Ni, K, Se, Na, and Zn). For two and a half days continuous emissions data were recorded by laboratory-certified continuous emissions monitors for CO, NOx, 0-2, THC, and COq2 while the EPA reference method stack tests were being conducted for the other pollutants. In addition, a WDNR test team measured CO, 0-2, and flue gas temperature with a Rosemount portable combustion analyzer for several hours over the course of those two and a half days. The principal purpose behind the study was to evaluate the hazardous air emissions potential of a small industrial furnace firing a virgin wood fuel. To that end, it was hoped that a surrogate pollutant could be identified which would represent the levels of hazardous air emissions (e.g., benzene) present in the wood-fired furnace flue gases. If a readily monitorable pollutant could be identified, then a regulatory strategy of measuring one representative pollutant could be put in place to continually assess the hazardous emissions potential of virgin wood combustion. (UK)

Survey of knowledge of hazards of chemicals potentially associated with the advanced isotope separation processes

International Nuclear Information System (INIS)

Chester, R.O.; Kirkscey, K.A.; Randolph, M.L.

1979-09-01

Hazards of chemical potentially associated with the advanced isotope separation processes are estimated based on open literature references. The tentative quantity of each chemical associated with the processes and the toxicity of the chemical are used to estimate this hazard. The chemicals thus estimated to be the most potentially hazardous to health are fluorine, nitric acid, uranium metal, uranium hexafluoride, and uranium dust. The estimated next most hazardous chemicals are bromine, hydrobromic acid, hydrochloric acid, and hydrofluoric acid. For each of these chemicals and for a number of other process-associated chemicals the following information is presented: (1) any applicable standards, recommended standards and their basis; (2) a brief discussion to toxic effects including short exposure tolerance, atmospheric concentration immediately hazardous to life, evaluation of exposures, recommended control procedures, chemical properties, and a list of any toxicology reviews; and (3) recommendations for future research

Survey of knowledge of hazards of chemicals potentially associated with the advanced isotope separation processes

Energy Technology Data Exchange (ETDEWEB)

Chester, R.O.; Kirkscey, K.A.; Randolph, M.L.

1979-09-01

Hazards of chemical potentially associated with the advanced isotope separation processes are estimated based on open literature references. The tentative quantity of each chemical associated with the processes and the toxicity of the chemical are used to estimate this hazard. The chemicals thus estimated to be the most potentially hazardous to health are fluorine, nitric acid, uranium metal, uranium hexafluoride, and uranium dust. The estimated next most hazardous chemicals are bromine, hydrobromic acid, hydrochloric acid, and hydrofluoric acid. For each of these chemicals and for a number of other process-associated chemicals the following information is presented: (1) any applicable standards, recommended standards and their basis; (2) a brief discussion to toxic effects including short exposure tolerance, atmospheric concentration immediately hazardous to life, evaluation of exposures, recommended control procedures, chemical properties, and a list of any toxicology reviews; and (3) recommendations for future research.

Characterization of the Potential Hazards Associated with Potential RCRA Treatment Noncompliances

Energy Technology Data Exchange (ETDEWEB)

Clark, David Lewis [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

2015-08-20

The purpose of this document is to provide a hazard evaluation of the noncompliances and whether any new actions are required to mitigate potential risk to the worker or the public. In short, we have reviewed the noncompliances and have concluded that the possibility of exothermic reactions leading to radioactive release is not credible, and in one case, inconceivable, stemming from the fact that the majority fraction of the waste is compatible with organic absorbents and neutralizers. It is not expected that the noncompliances would generate or produce uncontrolled flammable fumes, gases, extreme heat, pressure, fire, explosions, or violent reactions.

Radiation hazards

International Nuclear Information System (INIS)

Rausch, L.

1979-01-01

On a scientific basis and with the aid of realistic examples, the author gives a popular introduction to an understanding and judgment of the public discussion over radiation hazards: Uses and hazards of X-ray examinations, biological radiation effects, civilisation risks in comparison, origins and explanation of radiation protection regulations. (orig.) [de

Potential of Biological Agents in Decontamination of Agricultural Soil

Directory of Open Access Journals (Sweden)

Muhammad Kashif Javaid

2016-01-01

Full Text Available Pesticides are widely used for the control of weeds, diseases, and pests of cultivated plants all over the world, mainly since the period after the Second World War. The use of pesticides is very extensive to control harm of pests all over the globe. Persistent nature of most of the synthetic pesticides causes serious environmental concerns. Decontamination of these hazardous chemicals is very essential. This review paper elaborates the potential of various biological agents in decontamination of agricultural soils. The agricultural crop fields are contaminated by the periodic applications of pesticides. Biodegradation is an ecofriendly, cost-effective, highly efficient approach compared to the physical and chemical methods which are expensive as well as unfriendly towards environment. Biodegradation is sensitive to the concentration levels of hydrogen peroxide and nitrogen along with microbial community, temperature, and pH changes. Experimental work for optimum conditions at lab scale can provide very fruitful results about specific bacterial, fungal strains. This study revealed an upper hand of bioremediation over physicochemical approaches. Further studies should be carried out to understand mechanisms of biotransformation.

Potential of Biological Agents in Decontamination of Agricultural Soil.

Science.gov (United States)

Javaid, Muhammad Kashif; Ashiq, Mehrban; Tahir, Muhammad

2016-01-01

Pesticides are widely used for the control of weeds, diseases, and pests of cultivated plants all over the world, mainly since the period after the Second World War. The use of pesticides is very extensive to control harm of pests all over the globe. Persistent nature of most of the synthetic pesticides causes serious environmental concerns. Decontamination of these hazardous chemicals is very essential. This review paper elaborates the potential of various biological agents in decontamination of agricultural soils. The agricultural crop fields are contaminated by the periodic applications of pesticides. Biodegradation is an ecofriendly, cost-effective, highly efficient approach compared to the physical and chemical methods which are expensive as well as unfriendly towards environment. Biodegradation is sensitive to the concentration levels of hydrogen peroxide and nitrogen along with microbial community, temperature, and pH changes. Experimental work for optimum conditions at lab scale can provide very fruitful results about specific bacterial, fungal strains. This study revealed an upper hand of bioremediation over physicochemical approaches. Further studies should be carried out to understand mechanisms of biotransformation.

Tourism hazard potentials in Mount Merapi: how to deal with the risk

Science.gov (United States)

Muthiah, J.; Muntasib, E. K. S. H.; Meilani, R.

2018-05-01

Mount Merapi as one of the most popular natural tourism destination in Indonesia, indicated as disaster prone area. Hazard management is required to ensure visitors safety. Hazard identification and mapping are prerequisite in developing proper hazard management recommendation. This study aimed to map hazard potentials’ geographical positions obtained with geographical positioning system and to identify the hazard management being implemented. Data collection was carried out in Mei – June 2017 through observation and interview. Hiking trail and Lava tour area was selected as the study site, since the sites are the main areas for tourism activities in Mount Merapi. The type of hazards found in the area included lava, tephra, eruption cloud, ash, earthquake, land slide, extreme weather, slope and loose rock. Early warning system had been developed in this area, however the mechanism to regulate tourism activities still had to be improved. Local tourism entrepreneurs should be involved in the network of early warning system stakeholders to ensure tourist safety, and their capacity should be improved in order to be able to perform the measures needed for handling accident and disaster occurrences. Interpretive media explaining hazard potentials may be used to improve visitors’ awareness and ability to cope with the risk.

EFSA BIOHAZ Panel (EFSA Panel on Biological Hazards, 2013. Scientific Opinion on the public health hazards to be covered by inspection of meat from sheep and goats

DEFF Research Database (Denmark)

Hald, Tine; Baggesen, Dorte Lau

A risk ranking process identified Toxoplasma gondii and pathogenic verocytotoxin-producing Escherichia coli (VTEC) as the most relevant biological hazards for meat inspection of sheep and goats. As these are not detected by traditional meat inspection, a meat safety assurance system using risk......-based interventions was proposed. Further studies are required on T. gondii and pathogenic VTEC. If new information confirms these hazards as a high risk to public health from meat from sheep or goats, setting targets at carcass level should be considered. Other elements of the system are risk...... the extensive production systems used, and the ranking of chemical substances, which should be regularly updated and include new hazards. Control programmes across the food chain, national residue control plans, feed control and monitoring of environmental contaminants should be better integrated. Meat...

Potentials of ionizing radiation in reducing hazards to man and environment

Energy Technology Data Exchange (ETDEWEB)

Mullie, W C; Van Laerhoven, M J.A.M.; Kroes, R

1991-07-01

The main goal of the title study was to compare a relevant number of conventional processes and technologies for a range of uses with the application of ionizing radiation technology. Special emphasis is given to the hazardous effects of contemporary processes and chemicals on man and environment and to the potential role of the radiation processing technology, gamma irradiation in particular, in reducing these hazards. Based on their quantities and on (eco)toxicological criteria, four fields of application were identified a priori as potentially of interest for radiation processing. These fields of application are food preservation, sterilization and sanitization of pharmaceuticals and cosmetics, waste water and drinking water disinfection, and disinfection of sewage sludge and infectious hospital waste. Other fields of application as mentioned above are discussed in a more general matter. 12 figs., 31 tabs., 4 apps., refs.

Experimental investigation to evaluate the potential environmental hazards of photovoltaic panels

Energy Technology Data Exchange (ETDEWEB)

Tammaro, Marco, E-mail: marco.tammaro@enea.it [ENEA, Italian National Agency for New Technologies, Energy and the Environment, Centre of Research of Portici Naples (Italy); Salluzzo, Antonio, E-mail: antonio.salluzzo@enea.it [ENEA, Italian National Agency for New Technologies, Energy and the Environment, Centre of Research of Portici Naples (Italy); Rimauro, Juri, E-mail: juri.rimauro@enea.it [ENEA, Italian National Agency for New Technologies, Energy and the Environment, Centre of Research of Portici Naples (Italy); Schiavo, Simona, E-mail: simona.schiavo@unina.it [University “Federico II” of Naples Via Università 100, 80055 Portici (Italy); Manzo, Sonia, E-mail: sonia.manzo@enea.it [ENEA, Italian National Agency for New Technologies, Energy and the Environment, Centre of Research of Portici Naples (Italy)

2016-04-05

Highlights: • We measure the metals released in the leaching solution by samples of PV panels. • We measure the environmental effects by a battery of ecotoxicological tests. • The experimental data are compared with the European and Italian benchmark limits. • We assess the potential emissions of metals from future PV waste. • Experimental results show that the photovoltaic panels present an environmental risk. - Abstract: Recently the potential environmental hazard of photovoltaic modules together with their management as waste has attracted the attention of scientists. Particular concern is aroused by the several metals contained in photovoltaic panels whose potential release in the environment were scarcely investigated. Here, for the first time, the potential environmental hazard of panels produced in the last 30 years was investigated through the assessment of up to 18 releasable metals. Besides, the corresponding ecotoxicological effects were also evaluated. Experimental data were compared with the current European and Italian law limits for drinking water, discharge on soil and landfill inert disposal in order to understand the actual pollution load. Results showed that less than 3% of the samples respected all law limits and around 21% was not ecotoxic. By considering the technological evolutions in manufacturing, we have shown that during the years crystalline silicon panels have lower tendency to release hazardous metals with respect to thin film panels. In addition, a prediction of the amounts of lead, chromium, cadmium and nickel releasable from next photovoltaic waste was performed. The prevision up to 2050 showed high amounts of lead (30 t) and cadmium (2.9 t) releasable from crystalline and thin film panels respectively.

Influence of potential sea level rise on societal vulnerability to hurricane storm-surge hazards, Sarasota County, Florida

Science.gov (United States)

Frazier, Tim G.; Wood, Nathan; Yarnal, Brent; Bauer, Denise H.

2010-01-01

Although the potential for hurricanes under current climatic conditions continue to threaten coastal communities, there is concern that climate change, specifically potential increases in sea level, could influence the impacts of future hurricanes. To examine the potential effect of sea level rise on community vulnerability to future hurricanes, we assess variations in socioeconomic exposure in Sarasota County, FL, to contemporary hurricane storm-surge hazards and to storm-surge hazards enhanced by sea level rise scenarios. Analysis indicates that significant portions of the population, economic activity, and critical facilities are in contemporary and future hurricane storm-surge hazard zones. The addition of sea level rise to contemporary storm-surge hazard zones effectively causes population and asset (infrastructure, natural resources, etc) exposure to be equal to or greater than what is in the hazard zone of the next higher contemporary Saffir–Simpson hurricane category. There is variability among communities for this increased exposure, with greater increases in socioeconomic exposure due to the addition of sea level rise to storm-surge hazard zones as one progresses south along the shoreline. Analysis of the 2050 comprehensive land use plan suggests efforts to manage future growth in residential, economic and infrastructure development in Sarasota County may increase societal exposure to hurricane storm-surge hazards.

Hazards assessment for the Hazardous Waste Storage Facility

International Nuclear Information System (INIS)

Knudsen, J.K.; Calley, M.B.

1994-04-01

This report documents the hazards assessment for the Hazardous Waste Storage Facility (HWSF) located at the Idaho National Engineering Laboratory. The hazards assessment was performed to ensure that this facility complies with DOE and company requirements pertaining to emergency planning and preparedness for operational emergencies. The hazards assessment identifies and analyzes hazards that are significant enough to warrant consideration in a facility's operational emergency management program. The area surrounding HWSF, the buildings and structures at HWSF, and the processes used at HWSF are described in this report. All nonradiological hazardous materials at the HWSF were identified (radiological hazardous materials are not stored at HWSF) and screened against threshold quantities according to DOE Order 5500.3A guidance. Two of the identified hazardous materials exceeded their specified threshold quantity. This report discusses the potential release scenarios and consequences associated with an accidental release for each of the two identified hazardous materials, lead and mercury. Emergency considerations, such as emergency planning zones, emergency classes, protective actions, and emergency action levels, are also discussed based on the analysis of potential consequences. Evaluation of the potential consequences indicated that the highest emergency class for operational emergencies at the HWSF would be a Site Area Emergency

Radon-hazard potential the Beaver basin, Utah

International Nuclear Information System (INIS)

Bishop, C.E.

1995-01-01

Indoor-radon levels in the Beaver basin of southwestern Utah are the highest recorded to date in Utah, ranging from 17.5 to 495 picocuries per liter (pCi/L). Because the U.S. Environment Protection Agency considers indoor-radon levels above 4 pCi/L to represent a risk of lung cancer from long-term exposure, the Utah Geological Survey is preparing a radon-hazard-potential map for the area to help prioritize indoor testing and evaluate the need for radon-resistant construction. Radon is a chemically inert radioactive gas derived from the decay of uranium-238, which is commonly found in rocks and soils. Soil permeability, depth to ground water, and uranium/thorium content of source materials control the mobility and concentration of radon in the soil. Once formed, radon diffuses into the pore space of the soil and then to the atmosphere or into buildings by pressure-driven flow of air or additional diffusion. The Beaver basin has been a topographic and structural depression since late Miocene time. Paleocene to Miocene volcanic and igneous rocks border the basin. Uraniferous alluvial-fan, piedmont-slope, flood-plain, and lacustrine sediments derived from the surrounding volcanic rocks fill the basin. A soil-gas radon and ground radioactivity survey in the Beaver basin shows that soils have high levels of radon gas. In this survey, uranium concentrations range from 3 to 13 parts per million (ppm) and thorium concentrations range from 10 to 48 ppm. Radon concentrations in the soil gas ranged from 85 to 3,500 pCi/L. The highest concentrations of uranium, thorium, and radon gas and the highest radon-hazard-potential are in the well-drained permeable soils in the lower flood- plain deposits that underlie the city of Beaver

A calculational methodology for comparing the accident, occupational, and waste-disposal hazards of fusion reactor designs

International Nuclear Information System (INIS)

Fetter, S.

1985-01-01

A methodology has been developed for calculating indices of three classes of radiological hazards: reactor accidents, occupational exposures, and waste-disposal hazards. Radionuclide inventories, biological hazard potentials (BHP), and various dose-related indices are calculated. In the case of reactor accidents, the critical, 50-year and chronic dose are computed, as well as the number of early deaths and illnesses and late cancer fatalities. For occupational exposure, the contact dose rate is calculated for several times after reactor shutdown. In the case of waste-disposal hazards, the intruder dose and the intruder hazard potential (IHP) are calculated. Sample calculations for the MARS reactor design show the usefulness of the methodology in exploring design improvements

Macroscopic Quantum-Type Potentials in Theoretical Systems Biology

Directory of Open Access Journals (Sweden)

Laurent Nottale

2013-12-01

Full Text Available We review in this paper the use of the theory of scale relativity and fractal space-time as a tool particularly well adapted to the possible development of a future genuine systems theoretical biology. We emphasize in particular the concept of quantum-type potentials, since, in many situations, the effect of the fractality of space—or of the underlying medium—can be reduced to the addition of such a potential energy to the classical equations of motion. Various equivalent representations—geodesic, quantum-like, fluid mechanical, stochastic—of these equations are given, as well as several forms of generalized quantum potentials. Examples of their possible intervention in high critical temperature superconductivity and in turbulence are also described, since some biological processes may be similar in some aspects to these physical phenomena. These potential extra energy contributions could have emerged in biology from the very fractal nature of the medium, or from an evolutive advantage, since they involve spontaneous properties of self-organization, morphogenesis, structuration and multi-scale integration. Finally, some examples of applications of the theory to actual biological-like processes and functions are also provided.

UV radiation hazards

International Nuclear Information System (INIS)

Henderson, A.R.

1987-01-01

Exposure to ultraviolet radiation (UVR) is, for most people, a daily occurrence. Significant quantities of ultraviolet are present in sunlight, and this environmental exposure usually greatly exceeds that necessary for vitamin D production, the only certain benefit of UVR. In addition, occupational exposure to artificial sources of UVR is commonly encountered in commerce, industry and medicine. Exposure to UVR can present a hazard, principally to the eyes and exposed areas of the skin. The potential for any given source of UVR to cause photobiological damage depends on the spectral composition of the incident radiation, the geometry of optical coupling into the tissues at risk, the spectral sensitivity to damage of the irradiated tissue, the total accumulated exposure, and the action of any biological repair processes. In the ultraviolet region the photobiological interactions of concern are mainly photochemical. Hazard analysis and radiation protection require an appropriate framework of radiation measurement for the quantitative assessment of exposure and for the specification of safe exposure limits

Hazards and hazard combinations relevant for the safety of nuclear power plants

Science.gov (United States)

Decker, Kurt; Brinkman, Hans; Raimond, Emmanuel

2017-04-01

The potential of the contemporaneous impact of different, yet causally related, hazardous events and event cascades on nuclear power plants is a major contributor to the overall risk of nuclear installations. In the aftermath of the Fukushima accident, which was caused by a combination of severe ground shaking by an earthquake, an earthquake-triggered tsunami and the disruption of the plants from the electrical grid by a seismically induced landslide, hazard combinations and hazard cascades moved into the focus of nuclear safety research. We therefore developed an exhaustive list of external hazards and hazard combinations which pose potential threats to nuclear installations in the framework of the European project ASAMPSAE (Advanced Safety Assessment: Extended PSA). The project gathers 31 partners from Europe, North Amerika and Japan. The list comprises of exhaustive lists of natural hazards, external man-made hazards, and a cross-correlation matrix of these hazards. The hazard list is regarded comprehensive by including all types of hazards that were previously cited in documents by IAEA, the Western European Nuclear Regulators Association (WENRA), and others. 73 natural hazards and 24 man-made external hazards are included. Natural hazards are grouped into seismotectonic hazards, flooding and hydrological hazards, extreme values of meteorological phenomena, rare meteorological phenomena, biological hazards / infestation, geological hazards, and forest fire / wild fire. The list of external man-made hazards includes industry accidents, military accidents, transportation accidents, pipeline accidents and other man-made external events. The large number of different hazards results in the extremely large number of 5.151 theoretically possible hazard combinations (not considering hazard cascades). In principle all of these combinations are possible to occur by random coincidence except for 82 hazard combinations that - depending on the time scale - are mutually

Handbook of hazardous waste management

International Nuclear Information System (INIS)

Metry, A.A.

1980-01-01

The contents of this work are arranged so as to give the reader a detailed understanding of the elements of hazardous waste management. Generalized management concepts are covered in Chapters 1 through 5 which are entitled: Introduction, Regulations Affecting Hazardous Waste Management, Comprehensive Hazardous Waste Management, Control of Hazardous Waste Transportation, and Emergency Hazardous Waste Management. Chapters 6 through 11 deal with treatment concepts and are entitled: General Considerations for Hazardous Waste Management Facilities, Physical Treatment of Hazardous Wastes, Chemical Treatment of Hazardous Wastes, Biological Treatment of Hazardous Wastes, Incineration of Hazardous Wastes, and Hazardous Waste Management of Selected Industries. Chapters 12 through 15 are devoted to ultimate disposal concepts and are entitled: Land Disposal Facilities, Ocean Dumping of Hazardous Wastes, Disposal of Extremely Hazardous Wastes, and Generalized Criteria for Hazardous Waste Management Facilities

Hazard Potential of Volcanic Flank Collapses Raised by New Megatsunami Evidence

Science.gov (United States)

Ramalho, R. S.; Winckler, G.; Madeira, J.; Helffrich, G. R.; Hipólito, A.; Quartau, R.; Adena, K.; Schaefer, J. M.

2015-12-01

Large-scale gravitational flank collapses of steep volcanic islands are hypothetically capable of triggering megatsunamis with highly catastrophic effects. Yet evidence for the existence and impact of collapsed-triggered megatsunamis and their run-up heights remains scarce and/or is highly contentious. Therefore a considerable debate still exists over the potential magnitude of collapse-triggered tsunamis and their inherent hazard. In particular, doubts still remain whether or not large-scale flank failures typically generate enough volume flux to result in megatsunamis, or alternatively operate by slow-moving or multiple smaller episodic failures with much lower tsunamigenic potential. Here we show that one of the tallest and most active oceanic volcanoes on Earth - Fogo, in the Cape Verde Islands - collapsed catastrophically and triggered a megatsunami with devastating near-field effects ~73,000 years ago. Our deductions are based on the recent discovery and cosmogenic 3He dating of tsunamigenic deposits - comprising fields of stranded megaclasts, chaotic conglomerates, and sand sheets - found on the adjacent Santiago Island, which attest to the impact of this megatsunami and document wave run-up heights exceeding 270 m. The evidence reported here implies that Fogo's flank failure involved at least one sudden and voluminous event that resulted in a megatsunami, in contrast to what has been suggested before. Our work thus provides another line of evidence that large-scale flank failures at steep volcanic islands may indeed happen catastrophically and are capable of triggering tsunamis of enormous height and energy. This new line of evidence therefore reinforces the hazard potential of volcanic island collapses and stands as a warning that such hazard should not be underestimated, particularly in areas where volcanic island edifices are close to other islands or to highly populated continental margins.

Reactions of plutonium and uranium with water: Kinetics and potential hazards

International Nuclear Information System (INIS)

Haschke, J.M.

1995-12-01

The chemistry and kinetics of reactions between water and the metals and hydrides of plutonium and uranium are described in an effort to consolidate information for assessing potential hazards associated with handling and storage. New experimental results and data from literature sources are presented. Kinetic dependencies on pH, salt concentration, temperature and other parameters are reviewed. Corrosion reactions of the metals in near-neutral solutions produce a fine hydridic powder plus hydrogen. The corrosion rate for plutonium in sea water is a thousand-fold faster than for the metal in distilled water and more than a thousand-fold faster than for uranium in sea water. Reaction rates for immersed hydrides of plutonium and uranium are comparable and slower than the corrosion rates for the respective metals. However, uranium trihydride is reported to react violently if a quantity greater than twenty-five grams is rapidly immersed in water. The possibility of a similar autothermic reaction for large quantities of plutonium hydride cannot be excluded. In addition to producing hydrogen, corrosion reactions convert the massive metals into material forms that are readily suspended in water and that are aerosolizable and potentially pyrophoric when dry. Potential hazards associated with criticality, environmental dispersal, spontaneous ignition and explosive gas mixtures are outlined

POTENTIAL HAZARDS OF SEDIMENT IN KENDARI BAY, SOUTHEAST SULAWESI

Directory of Open Access Journals (Sweden)

Nur Adi Kristanto

2017-07-01

Full Text Available Kendari bay is located in front of Kendari city. There are two harbors in the inner part of bay which very important to support economic activities such as shipping and passenger transportation. The result of coastal characteristic mapping and physical oceanography survey show various coastal morphology, vegetation, weathering processes, sedimentation, currents, and water depth and sea floor morphology. Kendari bay is an enclosed bay; the area is wide in the inner part and narrow in mouth of bay (outlet, the morphology look like a bottle’s neck. Numerous mouth rivers are concentrate around the bay. The rivers load material from land since erosion on land is intensive enough. There is indication that sediment supplies from land trough river mouth not equivalent with outlet capacity. Sediment load is trapped in the inner bay caused the outlet morphology. So high sediment rate play an important role in the process of shallow of water depth in Kendari bay. This condition make the Kendari bay is a prone area of sediment hazard due to height rate of sedimentary process. Therefore, to anticipate the hazards, precaution should be taken related to the Kendari bay as the center of activities in southeast of Sulawesi. The further survey is needed such as marine geotechnique and on land environmental to collect data, which can be used as database for development planning. Key words: Potential hazard, sediment, Kendari Bay Teluk

Potential environmental impacts of light-emitting diodes (LEDs): metallic resources, toxicity, and hazardous waste classification.

Science.gov (United States)

Lim, Seong-Rin; Kang, Daniel; Ogunseitan, Oladele A; Schoenung, Julie M

2011-01-01

Light-emitting diodes (LEDs) are advertised as environmentally friendly because they are energy efficient and mercury-free. This study aimed to determine if LEDs engender other forms of environmental and human health impacts, and to characterize variation across different LEDs based on color and intensity. The objectives are as follows: (i) to use standardized leachability tests to examine whether LEDs are to be categorized as hazardous waste under existing United States federal and California state regulations; and (ii) to use material life cycle impact and hazard assessment methods to evaluate resource depletion and toxicity potentials of LEDs based on their metallic constituents. According to federal standards, LEDs are not hazardous except for low-intensity red LEDs, which leached Pb at levels exceeding regulatory limits (186 mg/L; regulatory limit: 5). However, according to California regulations, excessive levels of copper (up to 3892 mg/kg; limit: 2500), Pb (up to 8103 mg/kg; limit: 1000), nickel (up to 4797 mg/kg; limit: 2000), or silver (up to 721 mg/kg; limit: 500) render all except low-intensity yellow LEDs hazardous. The environmental burden associated with resource depletion potentials derives primarily from gold and silver, whereas the burden from toxicity potentials is associated primarily with arsenic, copper, nickel, lead, iron, and silver. Establishing benchmark levels of these substances can help manufacturers implement design for environment through informed materials substitution, can motivate recyclers and waste management teams to recognize resource value and occupational hazards, and can inform policymakers who establish waste management policies for LEDs.

The use of animals as a surveillance tool for monitoring environmental health hazards, human health hazards and bioterrorism.

Science.gov (United States)

Neo, Jacqueline Pei Shan; Tan, Boon Huan

2017-05-01

This review discusses the utilization of wild or domestic animals as surveillance tools for monitoring naturally occurring environmental and human health hazards. Besides providing early warning to natural hazards, animals can also provide early warning to societal hazards like bioterrorism. Animals are ideal surveillance tools to humans because they share the same environment as humans and spend more time outdoors than humans, increasing their exposure risk. Furthermore, the biologically compressed lifespans of some animals may allow them to develop clinical signs more rapidly after exposure to specific pathogens. Animals are an excellent channel for monitoring novel and known pathogens with outbreak potential given that more than 60 % of emerging infectious diseases in humans originate as zoonoses. This review attempts to highlight animal illnesses, deaths, biomarkers or sentinel events, to remind human and veterinary public health programs that animal health can be used to discover, monitor or predict environmental health hazards, human health hazards, or bioterrorism. Lastly, we hope that this review will encourage the implementation of animals as a surveillance tool by clinicians, veterinarians, ecosystem health professionals, researchers and governments. Copyright © 2017 The Authors. Published by Elsevier B.V. All rights reserved.

A suggested approach to the selection of chemical and biological protective clothing--meeting industry and emergency response needs for protection against a variety of hazards.

Science.gov (United States)

Stull, Jeffrey O

2004-01-01

The paper describes the development of a comprehensive decision logic for selection and use of biological and chemical protective clothing (BCPC). The decision logic recognizes the separate areas of BCPC use among emergency, biological, and chemical hazards. The proposed decision logic provides a system for type classifying BCPC in terms of its compliance with existing standards (for emergency applications), the overall clothing integrity, and the material barrier performance. Type classification is offered for garments, gloves, footwear, and eye/face protection devices. On the basis of multiple, but simply designed flowcharts, the type of BCPC appropriate for specific biological and chemical hazards can be selected. The decision logic also provides supplemental considerations for choosing appropriate BCPC features.

Identification of potential hazards associated with new residential construction.

Science.gov (United States)

Methner, M M

2000-02-01

There were several advantages and limitations of this observational study. The most important advantage of this study was the opportunity to observe residential construction workers performing their jobs. By observing work practices, valuable information was gathered about specific trades and their potential exposure to various chemical and physical agents. This information will be useful in guiding subsequent exposure assessments. Probably the greatest limitation of this study was the lack of participation by homebuilders. Ideally, observations of construction processes would have been more objective if the study included the participation of more than one homebuilder. Aside from one worker who was observed to wear safety glasses, leather gloves, and a dust mask, virtually no personal protective equipment (PPE) was observed onsite. Often small contractors do not have the financial resources necessary to procure the appropriate PPE and issue these items to the workers. Based on hazard prevalence, professional judgement, and the degree of hazardous product use, potential exposures that warrant quantitative sampling efforts during Phase 2 of this study are: bulldozer/backhoe operators--noise, vibration, diesel exhaust; concrete workers--naphtha, mineral spirits, Portland cement; asphalt workers--petroleum hydrocarbons, asphalt, mineral spirits; plumbers--methylethyl ketone, acetone, tetrahydrofuran, cyclohexanone; drywall finishers--total and respirable dust, hexane, acetone; painters--ethylene glycol, VOCs; masons--dust (during the preparation of mortar); floor preparation technicians--total and respirable dust; and ceramic tile installers--toluene, naphtha, silica (from grout powder).

Fire hazard analysis of the radioactive mixed waste trenchs

International Nuclear Information System (INIS)

McDonald, K.M.

1995-01-01

This Fire Hazards Analysis (FHA) is intended to assess comprehensively the risk from fire associated with the disposal of low level radioactive mixed waste in trenches within the lined landfills, provided by Project W-025, designated Trench 31 and 34 of the Burial Ground 218-W-5. Elements within the FHA make recommendations for minimizing risk to workers, the public, and the environment from fire during the course of the operation's activity. Transient flammables and combustibles present that support the operation's activity are considered and included in the analysis. The graded FHA contains the following elements: description of construction, protection of essential safety class equipment, fire protection features, description of fire hazards, life safety considerations, critical process equipment, high value property, damage potential--maximum credible fire loss (MCFL) and maximum possible fire loss (MPFL), fire department/brigade response, recovery potential, potential for a toxic, biological and/or radiation incident due to a fire, emergency planning, security considerations related to fire protection, natural hazards (earthquake, flood, wind) impact on fire safety, and exposure fire potential, including the potential for fire spread between fire areas. Recommendations for limiting risk are made in the text of this report and printed in bold type. All recommendations are repeated in a list in Section 18.0

EFSA BIOHAZ Panel (EFSA Panel on Biological Hazards), 2013. Scientific Opinion on Bioreduction application

DEFF Research Database (Denmark)

Hald, Tine; Baggesen, Dorte Lau

A method for on-farm containment of animal by-products (ABPs), called a ‘Bioreduction’ system, was assessed. The material for containment is of ovine origin and classified as a Category (Cat.) 1 ABP material. The proposed process consists of an aerobic degradation of the ABP material in a vented...... the risks related to pathogens such as non-spore forming bacteria and viruses. However, it is highly improbable that the risks related to more resistant biological hazards can be reduced. The application does not provide clear information about the location of the system and the origin of the material...... the risk of aerogenic transmission of biological agents and it is accessible to living vectors. Moreover, there is a risk of release of pathogens to the environment when opening the vessel. Therefore, the whole system cannot be considered as a closed system. The proposed Bioreduction method cannot...

Control of biological hazards in cold smoked salmon production

DEFF Research Database (Denmark)

Huss, Hans Henrik; Embarek, Peter Karim Ben; Jeppesen, V.F.

1995-01-01

An outline of the common processing technology for cold smoked salmon in Denmark is presented. The safety hazards related to pathogenic bacteria, parasites and biogenic amines are discussed with special emphasis on hazards related to Clostridium botulinum and Listeria monocytogenes. Critical...... control points are identified for all hazards except growth of L. monocytogenes. For this reason a limitation of shelf life to three weeks at +5 degrees C far cold smoked vacuum-packed salmon having greater than or equal to 3% water phase salt is recommended...

F. Biological hazards of plutonium

International Nuclear Information System (INIS)

1976-01-01

Plutonium is an unavoidable result of present nuclear power programmes. Its predominant isotopes are extremely long-lived and very toxic if absorbed in the body. In view of the increasing potential for plutonium and man to come into contact, the consequences of any plutonium release into the environment should be scientifically examined. This report is an attempt to place in one document a fully referenced account of the on-going work in many areas. There are three sections. Part 1 deals with the amounts of plutonium available in the fuel cycle, its properties and the probability of routine or accidental release. Part 2 examines the ways in which plutonium can reach man, in particular through food chains or inhalation. Part 3 details the biological effects of plutonium once it is absorbed into the body, assesses the amounts likely to be harmful and discusses the adequacy of present standards for plutonium burdens. There are two appendices. The likely differences between Pu-239, the most studied isotope, and other plutonium isotopes or transuranic nuclides are outlined in Appendix A. Appendix B contains a fuller account of the ways in which the fate of ingested or inhaled plutonium have been determined

List of external hazards to be considered in ASAMPSA-E

International Nuclear Information System (INIS)

Decker, Kurt; Brinkman, Hans

2016-01-01

The current report includes an exhaustive list of external hazards posing potential threats to nuclear installations. The list comprises of both, natural and man-made external hazards. Also, a cross correlation matrix of the hazards is presented. The list is the starting point for the hazard analysis process in Level 1 PSA as outlined by IAEA (2010; SSG-3) and the definition of design basis as required by WENRA (2014; Reference Levels for Existing Reactors). The list is regarded comprehensive by including all types of hazards that were previously cited in documents by IAEA and WENRA-RHWG. 73 natural hazards (N1 to N73) and 24 man-made external hazards (M1 to M24) are included. Natural hazards are grouped into seismo-tectonic hazards, flooding and hydrological hazards, extreme values of meteorological phenomena, rare meteorological phenomena, biological hazards / infestation, geological hazards, and forest fire. The list of external man-made hazards includes industry accidents, military accidents, transportation accidents, pipeline accidents and other man-made external events. The dataset further contains information on hazard correlations. 577 correlations between individual hazards are identified and shown in a cross-correlation chart. Correlations discriminate between: (1) Causally connected hazards (cause-effect relation) where one hazard (e.g., liquefaction) may be caused by another hazard (e.g., earthquake); or where one hazard (e.g., high wind) is a prerequisite for a correlated hazard (e.g., storm surge). (authors)

Review of hazards to female reproductive health in veterinary practice.

Science.gov (United States)

Scheftel, Joni M; Elchos, Brigid L; Rubin, Carol S; Decker, John A

2017-04-15

OBJECTIVE To review publications that address female reproductive health hazards in veterinary practice, summarize best practices to mitigate reproductive risks, and identify current knowledge gaps. DESIGN Systematized review. SAMPLE English-language articles describing chemical, biological, and physical hazards present in the veterinary workplace and associations with adverse reproductive outcomes or recommendations for minimizing risks to female reproductive health. PROCEDURES Searches of the CAB abstracts database were performed in July 2012 and in May 2015 with the following search terms: veterinarians AND occupational hazards and vets.id AND occupational hazards.sh. Searches of the PubMed database were conducted in November 2012 and in May 2015 with the following medical subject heading terms: occupational exposure AND veterinarians; anesthetics, inhalation/adverse effects AND veterinarians; risk factors AND pregnancy AND veterinarians; pregnancy outcome AND veterinarians; and animal technicians AND occupational exposure. Two additional PubMed searches were completed in January 2016 with the terms disinfectants/toxicity AND female AND fertility/drug effects and veterinarians/psychology AND stress, psychological. No date limits were applied to searches. RESULTS 4 sources supporting demographic trends in veterinary medicine and 118 resources reporting potential hazards to female reproductive health were identified. Reported hazards included exposure to anesthetic gases, radiation, antineoplastic drugs, and reproductive hormones; physically demanding work; prolonged standing; and zoonoses. CONCLUSIONS AND CLINICAL RELEVANCE Demographic information suggested that an increasing number of women of reproductive age will be exposed to chemical, biological, and physical hazards in veterinary practice. Information on reproductive health hazards and minimizing risk, with emphasis on developing a safety-focused work culture for all personnel, should be discussed starting

Setting the scenario - potential hazards of the nuclear fuel cycle

International Nuclear Information System (INIS)

Berry, R.J.; McPhail, N.

1989-01-01

The range of nuclear fuel cycle services provided by the various plants belonging to BNFL throughout the UK are described. The Sellafield Reprocessing Plant as the site which has the greatest potential for radiological hazard is then considered in more detail. In particular the safety cycle designed to prevent radiological accidents at Sellafield, emergency planning, the consequences of a major accident at Sellafield and the medical arrangements in the event of an accident are all discussed. (UK)

Development of tools for integrated monitoring and assessment of hazardous substances and their biological effects in the Baltic Sea.

Science.gov (United States)

Lehtonen, Kari K; Sundelin, Brita; Lang, Thomas; Strand, Jakob

2014-02-01

The need to develop biological effects monitoring to facilitate a reliable assessment of hazardous substances has been emphasized in the Baltic Sea Action Plan of the Helsinki Commission. An integrated chemical-biological approach is vitally important for the understanding and proper assessment of anthropogenic pressures and their effects on the Baltic Sea. Such an approach is also necessary for prudent management aiming at safeguarding the sustainable use of ecosystem goods and Services. The BEAST project (Biological Effects of Anthropogenic Chemical Stress: Tools for the Assessment of Ecosystem Health) set out to address this topic within the BONUS Programme. BEAST generated a large amount of quality-assured data on several biological effects parameters (biomarkers) in various marine species in different sub-regions of the Baltic Sea. New indicators (biological response measurement methods) and management tools (integrated indices) with regard to the integrated monitoring approach were suggested.

Autopsy tissues as biological monitors of human exposure to environmental pollutants. A case study: Concentrations of metals and PCDD/Fs in subjects living near a hazardous waste incinerator.

Science.gov (United States)

Domingo, José L; García, Francisco; Nadal, Martí; Schuhmacher, Marta

2017-04-01

Human biomonitoring is of tremendous importance to prevent potential adverse effects derived from human exposure to chemicals. Blood and urine are among the biological monitors more frequently used. However, biological matrices such as breast milk, hair, nails, saliva, feces, teeth, and expired air are also often used. In addition, and focused mainly on long-term exposure, adipose tissue and other human tissues like bone, liver, brain or kidney, are also used as biological monitors of certain substances, especially for long-term biomonitoring. However, for this kind of tissues sampling is always a limiting factor. In this paper, we have examined the role of autopsy tissues as biological monitors of human exposure to environmental pollutants. For it, we have used a case study conducted near a hazardous waste incinerator (HWI) in Catalonia (Spain), in which the concentrations of metals and polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs), have been periodically determined in autopsy tissues of subjects living in the area under potential influence of the facility. This case study does not show advantages -in comparison to other appropriate biomonitors such as blood- in using autopsy tissues in the monitoring of long-term exposure to metals and PCDD/Fs. Copyright © 2017 Elsevier Inc. All rights reserved.

[Synthetic cannabinoids: spread, addiction biology & current perspective of personal health hazard].

Science.gov (United States)

Bonnet, U; Mahler, H

2015-04-01

Among the new psychoactive substances (NPS), most frequently synthetic cannabinoids (SCBs) have been found in Europe. These are sold as active compounds in e. g. so-called "herbal blends". When inhaled or ingested, besides intoxication symptoms, as they occur with heavy cannabis use (e. g., tachycardia, myocardial infarction, confusion, hallucinations, panic attacks, and paranoia), harmful effects (severe agitation, coma, catatonic stupor, hypertension, cardiac arrhythmia, dyspnoea, seizures, myoclonus, rhabdomyolysis, hyperthermia, diaphoresis, acute kidney injury, vomiting, headache, and hypokalemia) arise, which are mostly unusual about cannabis use. In addition, the first cases of addiction and death related to SCBs have been reported. Taking into account the newest literature and using an algorithm with two main criteria (addiction potential, toxicity), the authors made a first attempt to rank the personal health hazard of SCBs in comparison to that of other psychoactive drugs. Accordingly, the relative health hazard of SCBs is found to be somewhat higher than that of cannabis and lower than that of synthetic cathinones ("bath salts"). However, the toxicity of SCBs, is significantly greater than the toxicity of cannabis, thus being similar to that of synthetic cathinones and benzodiazepines. The addiction potential appears to be lower than that of synthetic cathinones, benzodiazepines, or cannabis. Due to the fluctuation of substances and the availability in internet resources, legislation is facing a serious "hare-hedgehog" problem to control the manufacture, trade and possession of SCBs. © Georg Thieme Verlag KG Stuttgart · New York.

GIS and RS-based modelling of potential natural hazard areas in Pehchevo municipality, Republic of Macedonia

Directory of Open Access Journals (Sweden)

Milevski Ivica

2013-01-01

Full Text Available In this paper, one approach of Geographic Information System (GIS and Remote Sensing (RS assessment of potential natural hazard areas (excess erosion, landslides, flash floods and fires is presented. For that purpose Pehchevo Municipality in the easternmost part of the Republic of Macedonia is selected as a case study area because of high local impact of natural hazards on the environment, social-demographic situation and local economy. First of all, most relevant static factors for each type of natural hazard are selected (topography, land cover, anthropogenic objects and infrastructure. With GIS and satellite imagery, multi-layer calculation is performed based on available traditional equations, clustering or discreditation procedures. In such way suitable relatively “static” natural hazard maps (models are produced. Then, dynamic (mostly climate related factors are included in previous models resulting in appropriate scenarios correlated with different amounts of precipitation, temperature, wind direction etc. Finally, GIS based scenarios are evaluated and tested with field check or very fine resolution Google Earth imagery showing good accuracy. Further development of such GIS models in connection with automatic remote meteorological stations and dynamic satellite imagery (like MODIS will provide on-time warning for coming natural hazard avoiding potential damages or even causalities.

A new hazard index for the determination of risk potentials of disposed radioactive wastes

International Nuclear Information System (INIS)

Kirchner, Gerald

1990-01-01

On the basis of a discussion of advantages and limitations of hazard calculations of nuclear waste, a new hazard index is presented. The model deals with environmental processes that determine radiation exposure to man after failure of a geologic repository and release of radionuclides into the biosphere. Included in the model are isotopic composition of the waste, probability for transport of nuclides to man, cycling in the biosphere, radiotoxicity to man and changes of the risk potential which are due to radioactive build-up and decay processes after the waste nuclides enter the biosphere. Nuclide-specific data necessary for the use of the new index are compiled. Calculations for wastes from different nuclear power reactor types and fuel cycle options indicate that 237 Np and 241 Am are the waste constituents with the most demanding requirements in regard to the long-term isolation potential of a repository. Isolation times required for the wastes analyzed are of the order of 10 7 years. Hazard analyses of nuclear wastes with negligible heat generation from various sources show that secondary wastes from nuclear fuel reprocessing and mixed-oxide fuel fabrication have long-term risk potentials which are about two orders of magnitude higher than those from other wastes. They should be disposed of together with high-level wastes. (author)

Endodontic radiology, practice, and knowledge of radiation biology, hazard, and protection among clinical dental students and interns

Directory of Open Access Journals (Sweden)

Joan Emien Enabulele

2015-01-01

Full Text Available Objective: To evaluate the practice and knowledge of endodontic radiology as well as assess the knowledge of radiation biology, hazard, and protection among clinical dental students and interns. Materials and Methods: Cross-sectional study of clinical dental students and interns at University of Benin and University of Benin Teaching hospital respectively. Data was collected using a questionnaire which covered practice and knowledge of endodontic radiography, knowledge of radiation biology, hazard, and protection. Data was analyzed using Statistical Package for Social Sciences (SPSS version 17.0. Result: Seventy participants were included in the study, 40% were final year students and 24.3% house officers. Majority (95.7% agreed that they exposed radiographs as part of endodontic treatment. Only 18.6% knew that the apices of teeth should be 3mm from the border of the X-ray film, while 24.3% knew that 3mm of periapical bone should be visible on X-ray. Less than half (31.4% knew that paralleling technique was the technique of choice for endodontic radiography and this was statistically Significant in relationship to the status of the of the respondents. A few (4.3% of the respondents had knowledge of new horizons in endodontic imaging. Half of the respondents knew that damage by X-rays is mainly due to formation of free radicals. The most frequently reported radiation hazards was reduced salivary flow, while the least reported was rampant caries. Most knew how to protect patients, themselves, and other persons while exposing radiographs. Conclusion: There is need for inclusion of endodontic radiography in the undergraduate curriculum to ensure proper and correct radiographs during endodontic procedure.

INTERNAL HAZARDS ANALYSIS FOR LICENSE APPLICATION

Energy Technology Data Exchange (ETDEWEB)

R.J. Garrett

2005-02-17

The purpose of this internal hazards analysis is to identify and document the internal hazards and potential initiating events associated with preclosure operations of the repository at Yucca Mountain. Internal hazards are those hazards presented by the operation of the facility and by its associated processes that can potentially lead to a radioactive release or cause a radiological hazard. In contrast to external hazards, internal hazards do not involve natural phenomena and external man-made hazards. This internal hazards analysis was performed in support of the preclosure safety analysis and the License Application for the Yucca Mountain Project. The methodology for this analysis provides a systematic means to identify internal hazards and potential initiating events that may result in a radiological hazard or radiological release during the repository preclosure period. These hazards are documented in tables of potential internal hazards and potential initiating events (Section 6.6) for input to the repository event sequence categorization process. The results of this analysis will undergo further screening and analysis based on the criteria that apply to the performance of event sequence analyses for the repository preclosure period. The evolving design of the repository will be re-evaluated periodically to ensure that internal hazards that have not been previously evaluated are identified.

INTERNAL HAZARDS ANALYSIS FOR LICENSE APPLICATION

International Nuclear Information System (INIS)

Garrett, R.J.

2005-01-01

The purpose of this internal hazards analysis is to identify and document the internal hazards and potential initiating events associated with preclosure operations of the repository at Yucca Mountain. Internal hazards are those hazards presented by the operation of the facility and by its associated processes that can potentially lead to a radioactive release or cause a radiological hazard. In contrast to external hazards, internal hazards do not involve natural phenomena and external man-made hazards. This internal hazards analysis was performed in support of the preclosure safety analysis and the License Application for the Yucca Mountain Project. The methodology for this analysis provides a systematic means to identify internal hazards and potential initiating events that may result in a radiological hazard or radiological release during the repository preclosure period. These hazards are documented in tables of potential internal hazards and potential initiating events (Section 6.6) for input to the repository event sequence categorization process. The results of this analysis will undergo further screening and analysis based on the criteria that apply to the performance of event sequence analyses for the repository preclosure period. The evolving design of the repository will be re-evaluated periodically to ensure that internal hazards that have not been previously evaluated are identified

Radiation hazards and their effects

International Nuclear Information System (INIS)

Lunu, Shyam; Kumar, Hemant; Joshi, Pankaj Kumar; Songara, Venkteshwer

2012-01-01

Radiation can be classified into ionizing radiation and non-ionizing radiation, based on whether it is capable of ionizing atoms and breaking chemical bonds. Ultraviolet and higher frequency such as X-rays, gamma rays are ionizing. These pose their own special hazards. Non ionizing radiation is associated with two major potential hazards. i.e. electrical and biological. Additionally includes electric current caused by radiation can generate sparks and create a fire or explosive hazards. Strong radiation can induce current capable of delivering an electric shock. Extremely high power electromagnetic radiation can cause electric currents strong enough to create sparks when an induced voltage exceeds the breakdown voltage of surrounding mediums. A 2009 study at the University of Basal in Switzerland found that intermitted exposure of human cells to a 50 Hz electromagnetic field at a flux density of 10 Gy induced a slight but significant increase of DNA fragmentation in the comet assay. Mobile phones radiation and health concerns have been raised, especially following the enormous increase in the use of wireless mobile telephony throughout the world. Mobile phones use electromagnetic radiation in the microwaves range and some believes this may be harmful to human health. (author)

Human biological monitoring for exposure assessment in response to an incident involving hazardous materials.

Science.gov (United States)

Scheepers, Paul T J; van Brederode, Nelly E; Bos, Peter M J; Nijhuis, Nicole J; van de Weerdt, Rik H J; van der Woude, Irene; Eggens, Martin L

2014-12-15

Biological monitoring in humans (HBM) is widely used in the field of occupational and environmental health. In the situation of an unexpected release of hazardous materials HBM may contribute to the medical support and treatment of exposed individuals from the general population or of emergency responders. Such exposure information may also be used to respond to individual concerns such as questions about a possible relationship between the chemicals released during the incident and health effects. In The Netherlands a guideline was prepared to support early decision-making about the possible use of HBM for exposure assessment during or as soon as possible following a chemical incident. The application of HBM in such an emergency setting is not much different from situations where HBM is normally used but there are some issues that need extra attention such as the choice of the biomarker, the biological media to be sampled, the time point at which biological samples should be collected, the ethics approval and technical implementation of the study protocol and the interpretation and communication of the study results. These issues addressed in the new guideline will support the use of HBM in the management of chemical disasters. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

CONTRASTING RESULTS OF POTENTIAL TSUNAMI HAZARDS IN MUISNE, CENTRAL COAST OF ECUADOR

Directory of Open Access Journals (Sweden)

Theofilos Toulkeridis

2017-02-01

Full Text Available After the 7.8 Mw Earthquake occurred in Ecuador on April 16 of 2016, the Ecuadorian Government declared the whole Island of Muisne into a risk hazard zone by a potential Tsunami impact and subsequent flooding. Based on the emitted resolution, human settlements in the affected area were prohibited, and a resettlement project in the village of Bunche is currently taking place. Nonetheless, our study demonstrates that the inundation chart used to release the mentioned resolution underestimate the flooding area in case of a real Tsunami impact. To support this conclusion, we present a new inundation chart for the three more probable scenarios, based on historical tsunami records and a seismic hazard assessment study in central coastal Ecuador.

Bioprocessing scenarios for mixed hazardous waste

International Nuclear Information System (INIS)

Wolfram, J.H.; Rogers, R.D.

1994-01-01

The potential of biological processing of mixed hazardous waste has not been determined. However, the use of selected microorganisms for the degradation and/or detoxification of hazardous organic compounds is gaining wide acceptance as an alternative waste treatment technology. The isolation of a unique strain of Pseudomonas Putida Idaho seems well adapted to withstand the demands of the input stream comprised of liquid scintillation waste. This paper describes the results from the continuous processing of a mixture comprised of p-xylene and surfactant as well as commercial liquid scintillation formulations. The two formulations tested contained xylene and pseudocumene as the solvent base. The process is now at the demonstration phase at one of DOE's facilities which has a substantial amount of stored waste of this type. The system at the DOE facility is comprised of two CSTR units in series

Biology of Leptoypha hospita (Hemiptera: Tingidae), a Potential Biological Control Agent of Chinese Privet

Science.gov (United States)

Yanzhuo Zhang; James L. Hanula; Scott Horn; Kristine Braman; Jianghua Sun

2011-01-01

The biology of Leptoypha hospita Drake et Poor (Hemiptera: Tingidae), a potential biological control agent from China for Chinese privet, Ligustrum sinense Lour., was studied in quarantine in the United States. Both nymphs and adults feed on Chinese privet mesophyll cells that lead to a bleached appearance of leaves and dieback of branch tips. L. hospita has five...

Hazard interactions and interaction networks (cascades) within multi-hazard methodologies

Science.gov (United States)

Gill, Joel C.; Malamud, Bruce D.

2016-08-01

This paper combines research and commentary to reinforce the importance of integrating hazard interactions and interaction networks (cascades) into multi-hazard methodologies. We present a synthesis of the differences between multi-layer single-hazard approaches and multi-hazard approaches that integrate such interactions. This synthesis suggests that ignoring interactions between important environmental and anthropogenic processes could distort management priorities, increase vulnerability to other spatially relevant hazards or underestimate disaster risk. In this paper we proceed to present an enhanced multi-hazard framework through the following steps: (i) description and definition of three groups (natural hazards, anthropogenic processes and technological hazards/disasters) as relevant components of a multi-hazard environment, (ii) outlining of three types of interaction relationship (triggering, increased probability, and catalysis/impedance), and (iii) assessment of the importance of networks of interactions (cascades) through case study examples (based on the literature, field observations and semi-structured interviews). We further propose two visualisation frameworks to represent these networks of interactions: hazard interaction matrices and hazard/process flow diagrams. Our approach reinforces the importance of integrating interactions between different aspects of the Earth system, together with human activity, into enhanced multi-hazard methodologies. Multi-hazard approaches support the holistic assessment of hazard potential and consequently disaster risk. We conclude by describing three ways by which understanding networks of interactions contributes to the theoretical and practical understanding of hazards, disaster risk reduction and Earth system management. Understanding interactions and interaction networks helps us to better (i) model the observed reality of disaster events, (ii) constrain potential changes in physical and social vulnerability

Transportation of Hazardous Evidentiary Material.

Energy Technology Data Exchange (ETDEWEB)

Osborn, Douglas.

2005-06-01

This document describes the specimen and transportation containers currently available for use with hazardous and infectious materials. A detailed comparison of advantages, disadvantages, and costs of the different technologies is included. Short- and long-term recommendations are also provided.3 DraftDraftDraftExecutive SummaryThe Federal Bureau of Investigation's Hazardous Materials Response Unit currently has hazardous material transport containers for shipping 1-quart paint cans and small amounts of contaminated forensic evidence, but the containers may not be able to maintain their integrity under accident conditions or for some types of hazardous materials. This report provides guidance and recommendations on the availability of packages for the safe and secure transport of evidence consisting of or contaminated with hazardous chemicals or infectious materials. Only non-bulk containers were considered because these are appropriate for transport on small aircraft. This report will addresses packaging and transportation concerns for Hazardous Classes 3, 4, 5, 6, 8, and 9 materials. If the evidence is known or suspected of belonging to one of these Hazardous Classes, it must be packaged in accordance with the provisions of 49 CFR Part 173. The anthrax scare of several years ago, and less well publicized incidents involving unknown and uncharacterized substances, has required that suspicious substances be sent to appropriate analytical laboratories for analysis and characterization. Transportation of potentially hazardous or infectious material to an appropriate analytical laboratory requires transport containers that maintain both the biological and chemical integrity of the substance in question. As a rule, only relatively small quantities will be available for analysis. Appropriate transportation packaging is needed that will maintain the integrity of the substance, will not allow biological alteration, will not react chemically with the substance being

EFSA Panel on Biological Hazards (BIOHAZ); Scientific Opinion on Composting on-farm of dead poultry

DEFF Research Database (Denmark)

Hald, Tine

EFSA’s Scientific Panel on Biological Hazards (BIOHAZ) was asked for a scientific opinion on two alternative methods for processing Category (Cat) 2 Animal By-Products (ABP). The material to be treated consists of poultry manure, straw and dead-on-farm poultry; this implies that the animals died...... due to a disease, which in most cases was not properly diagnosed. The proposed processes are composting methods to be used on-farm. The first method is a continuous open system where composting is done under roof in piles separated by wooden partition walls. The piles are processed without enforced...

Drug delivery and nanoparticles: Applications and hazards

Directory of Open Access Journals (Sweden)

Wim H De Jong

2008-06-01

Full Text Available Wim H De Jong1, Paul JA Borm2,31Laboratory for Toxicology, Pathology and Genetics, National Institute for Public Health and the Environment (RIVM, Bilthoven, The Netherlands; 2Zuyd University, Centre of Expertise in Life Sciences, Heerlen, The Netherlands; 3Magnamedics GmbH, Aachen, GermanyAbstract: The use of nanotechnology in medicine and more specifically drug delivery is set to spread rapidly. Currently many substances are under investigation for drug delivery and more specifically for cancer therapy. Interestingly pharmaceutical sciences are using nanoparticles to reduce toxicity and side effects of drugs and up to recently did not realize that carrier systems themselves may impose risks to the patient. The kind of hazards that are introduced by using nanoparticles for drug delivery are beyond that posed by conventional hazards imposed by chemicals in classical delivery matrices. For nanoparticles the knowledge on particle toxicity as obtained in inhalation toxicity shows the way how to investigate the potential hazards of nanoparticles. The toxicology of particulate matter differs from toxicology of substances as the composing chemical(s may or may not be soluble in biological matrices, thus influencing greatly the potential exposure of various internal organs. This may vary from a rather high local exposure in the lungs and a low or neglectable exposure for other organ systems after inhalation. However, absorbed species may also influence the potential toxicity of the inhaled particles. For nanoparticles the situation is different as their size opens the potential for crossing the various biological barriers within the body. From a positive viewpoint, especially the potential to cross the blood brain barrier may open new ways for drug delivery into the brain. In addition, the nanosize also allows for access into the cell and various cellular compartments including the nucleus. A multitude of substances are currently under investigation

Bioremediation of toxic and hazardous wastes by denitrifying bacteria

International Nuclear Information System (INIS)

Barraquio, Wilfredo L.

2005-01-01

This papers discusses the wastes coming rom domestic, industrial and agricultural sources are polluting the forests, rivers lakes, groundwater, and air and there are some measures like the physicochemical and biological measures are being utilized to remedy the destruction of resources; and of the measures, bioremediation offers great potential in cleaning up the environment of pollutants which is a cost-effective and environment-friendly technology that uses microorganisms to degrade hazardous substances into less toxic

Has land subsidence changed the flood hazard potential? A case example from the Kujukuri Plain, Chiba Prefecture, Japan

Directory of Open Access Journals (Sweden)

H. L. Chen

2015-11-01

Full Text Available Coastal areas are subject to flood hazards because of their topographic features, social development and related human activities. The Kujukuri Plain, Chiba Prefecture, Japan, is located nearby the Tokyo metropolitan area and it faces to the Pacific Ocean. In the Kujukuri Plain, widespread occurrence of land subsidence has been caused by exploitation of groundwater, extraction of natural gas dissolved in brine, and natural consolidation of the Holocene and landfill deposits. The locations of land subsidence include areas near the coast, and it may increase the flood hazard potential. Hence, it is very important to evaluate flood hazard potential by taking into account the temporal change of land elevation caused by land subsidence, and to prepare hazard maps for protecting the surface environment and for developing an appropriate land-use plan. In this study, flood hazard assessments at three different times, i.e., 1970, 2004, and 2013 are implemented by using a flood hazard model based on Multicriteria Decision Analysis with Geographical Information System techniques. The model incorporates six factors: elevation, depression area, river system, ratio of impermeable area, detention ponds, and precipitation. Main data sources used are 10 m resolution topography data, airborne laser scanning data, leveling data, Landsat-TM data, two 1:30 000 scale river watershed maps, and precipitation data from observation stations around the study area and Radar data. The hazard assessment maps for each time are obtained by using an algorithm that combines factors with weighted linear combinations. The assignment of the weight/rank values and their analysis are realized by the application of the Analytic Hierarchy Process method. This study is a preliminary work to investigate flood hazards on the Kujukuri Plain. A flood model will be developed to simulate more detailed change of the flood hazard influenced by land subsidence.

EFSA Panels on Biological Hazards (BIOHAZ), on Contaminants in the Food Chain (CONTAM), and on Animal Health and Welfare (AHAW); Scientific Opinion on the public health hazards to be covered by inspection of meat (poultry)

DEFF Research Database (Denmark)

Hald, Tine

2012-01-01

be risk categorisation of flocks based on FCI and classification of abattoirs according to their capability to reduce carcass faecal contamination. It is proposed that post-mortem visual inspection is replaced by setting targets for the main hazards on the carcass, and by verification of the food business......A qualitative risk assessment identified Campylobacter spp., Salmonella spp. and ESBL/AmpC gene-carrying bacteria as the most relevant biological hazards in the context of meat inspection of poultry. As none of these are detected by traditional visual meat inspection, establishing an integrated...... food safety assurance system, achievable through improved food chain information (FCI) and risk-based interventions, was proposed. This includes setting targets at carcass level and, when appropriate, flock level indicating what should be achieved for a given hazard. Elements of the system would...

Job Hazard Analysis

National Research Council Canada - National Science Library

1998-01-01

.... Establishing proper job procedures is one of the benefits of conducting a job hazard analysis carefully studying and recording each step of a job, identifying existing or potential job hazards...

Coal seam gas water: potential hazards and exposure pathways in Queensland.

Science.gov (United States)

Navi, Maryam; Skelly, Chris; Taulis, Mauricio; Nasiri, Shahram

2015-01-01

The extraction of coal seam gas (CSG) produces large volumes of potentially contaminated water. It has raised concerns about the environmental health impacts of the co-produced CSG water. In this paper, we review CSG water contaminants and their potential health effects in the context of exposure pathways in Queensland's CSG basins. The hazardous substances associated with CSG water in Queensland include fluoride, boron, lead and benzene. The exposure pathways for CSG water are (1) water used for municipal purposes; (2) recreational water activities in rivers; (3) occupational exposures; (4) water extracted from contaminated aquifers; and (5) indirect exposure through the food chain. We recommend mapping of exposure pathways into communities in CSG regions to determine the potentially exposed populations in Queensland. Future efforts to monitor chemicals of concern and consolidate them into a central database will build the necessary capability to undertake a much needed environmental health impact assessment.

75 FR 78918 - Hazardous Waste Management System; Identification and Listing of Hazardous Waste; Removal of...

Science.gov (United States)

2010-12-17

... and Community Right-to-Know Act FDA Food and Drug Administration HSWA Hazardous and Solid Waste...(f)), and hazardous substances (40 CFR 302.4) based solely upon the evidence that it is a potential... subsequently identified as hazardous wastes in Sec. 261.33(f) based solely on their potential for carcinogenic...

Chemical hazards from decontamination solutions in low level waste

International Nuclear Information System (INIS)

Leventhal, L.; Miller, A.; Turney, J.; Naughton, M.; IMPELL Corp., Walnut Creek, CA; Electric Power Research Inst., Palo Alto, CA)

1985-01-01

Recent regulations are focussing more attention on the non-radioactive matrix materials associated with radioactive wastes. Decontamination of operating facilities is becoming a more significant source of low-level waste. This study reviewed the chemical and biological hazards of over 50 decontamination processes. Seventeen of the most prominent hard and soft decontamination processes were examined in detail. The chemical and biological hazards of these seventeen are presented in this paper. These hazards influence the choice of radwaste processing and packaging operations and methods. Federal, state and local regulations further impact on operations and waste disposal. Hazards to personnel, in plant and off-site, resulting from the decontamination cycle are evaluated. 1 fig., 5 tabs

GRASPING THE NATURE OF POTENTIALLY HAZARDOUS ASTEROIDS

Energy Technology Data Exchange (ETDEWEB)

Perna, D.; Barucci, M. A.; Fornasier, S.; Deshapriya, J. D. P. [LESIA—Observatoire de Paris, PSL Research University, CNRS, Sorbonne Universités, UPMC Univ. Paris 06, Univ. Paris Diderot, Sorbonne Paris Cité, 5 place Jules Janssen, F-92195 Meudon (France); Dotto, E.; Ieva, S.; Epifani, E. Mazzotta [INAF—Osservatorio Astronomico di Roma, Via Frascati 33, I-00040 Monte Porzio Catone (Roma) (Italy); Bernardi, F. [SpaceDyS, via Mario Giuntini 63, I-56023 Cascina (Pisa) (Italy); Luise, F. De [INAF—Osservatorio Astronomico di Teramo, via Mentore Maggini snd, I-64100 Teramo (Italy); Perozzi, E. [Deimos Space, Strada Buchesti 75-77, Bucharest (Romania); Rossi, A. [IFAC—CNR, via Madonna del Piano 10, I-50019 Sesto Fiorentino (Firenze) (Italy); Micheli, M., E-mail: davide.perna@obspm.fr [ESA—NEOCC, ESRIN, via Galileo Galilei 64, I-00044 Frascati (Rome) (Italy)

2016-01-15

Through their delivery of water and organics, near-Earth objects (NEOs) played an important role in the emergence of life on our planet.  However, they also pose a hazard to the Earth, as asteroid impacts could significantly affect our civilization. Potentially hazardous asteroids (PHAs) are those that, in principle, could possibly impact the Earth within the next century, producing major damage. About 1600 PHAs are currently known, from an estimated population of 4700 ± 1450. However, a comprehensive characterization of the PHA physical properties is still missing. Here we present spectroscopic observations of 14 PHAs, which we have used to derive their taxonomy, meteorite analogs, and mineralogy. Combining our results with the literature, we investigated how PHAs are distributed as a function of their dynamical and physical properties. In general, the “carbonaceous” PHAs seem to be particularly threatening, because of their high porosity (limiting the effectiveness of the main deflection techniques that could be used in space) and low inclination and minimum orbit intersection distance (MOID) with the Earth (favoring more frequent close approaches). V-type PHAs also present low MOID values, which can produce frequent close approaches (as confirmed by the recent discovery of a limited space weathering on their surfaces). We also identified those specific objects that deserve particular attention because of their extreme rotational properties, internal strength, or possible cometary nature. For PHAs and NEOs in general, we identified a possible anti-correlation between the elongation and the rotational period, in the range of P{sub rot} ≈ 5–80 hr. This would be compatible with the behavior of gravity-dominated aggregates in rotational equilibrium. For periods ≳80–90 hr, such a trend stops, possibly under the influence of the YORP effect and collisions. However, the statistics is very low, and further observational and theoretical work is required

Areas of research in radiation chemistry fundamental to radiation biology

International Nuclear Information System (INIS)

Powers, E.L.

1980-01-01

Among all the environmental hazards to which man is exposed, ionizing radiation is the most thoroughly investigated and the most responsibly monitored and controlled. Nevertheless, because of the importance of radiation in modern society from both the hazard as well as the utilitarian standpoints, much more information concerning the biological effects induced and their modification and reversal is required. Together with radiation physics, an understanding of radiation chemistry is necessary for full appreciation of biological effects of high and low energy radiations, and for the development of prophylactic, therapeutic and potentiating methods and techniques in biological organisms. The necessity of understanding the chemistry of any system, biological or not, that is to be manipulated and controlled, is so obvious as to make trivial a statement to that effect. If any natural phenomenon is to be put to our use, surely the elements of it must be studied and appreciated fully. In the preliminary statements of the various panels of this general group, the need for additional information on the basic radiation chemistry concerned in radiation-induced biological effects pervades throughout

The Protective Role of Lettuce oil (Lactuca sativa) against Radiation induced Biological Hazards in Male Rats

International Nuclear Information System (INIS)

Abdel-Magied, N.; Ahmed, A.G.

2011-01-01

This study was conducted to clarify the potential role of lettuce oil against damages induced in rats due to exposure to gamma radiation. Adult male albino rats (120-150 g) were divided into 4 groups each of 12 animals. The first group was considered control animals. The second group received, via gavages, lettuce oil (200 mg/Kg body weight) for 3 weeks. The third group was subjected to a single dose of 6.5Gy whole body gamma irradiation. The fourth group received lettuce oil for 3 weeks then was exposed to radiation. Blood samples were collected 1 and 7 days post irradiation. Exposure of rats to gamma irradiation caused a significant increase in the level of glucose, total cholesterol (TC), triglycerides (TG), malondialdehyde (MDA) and follicle stimulating hormone (FSH) while a significant decrease was recorded in glutathione content (GSH), superoxide dismutase (SOD) and catalase activities, white blood cells (WBCs), red blood cells (RBCs), haemoglobin content (Hb), haematocrit percentage (Hct%), mean corpuscular volume (MCV), platelets (PLT), leutinizing hormone (LH) and testosterone hormone . In rats treated with lettuce oil then exposed to radiation, the results showed an improvement in all previous parameters. It could be concluded that lettuce oil might reduce the biological hazards in rats induced by gamma irradiation

Contribution of psychology to the safety of installations with a high hazard potential

International Nuclear Information System (INIS)

Wilpert, B.

1996-01-01

Installations with a high hazard potential are usually characterised by the dual attribute 'low risk - high hazard'. Diverse strategies of safety management are employed in such installations in order to limit the great hazard potential of safety-relevant occurrences (faults, abnormal operating states, accidents) that can take place in them. These strategies include specific control principles. In nuclear engineering, for example, the feedforward principle has already been used for some time as a tool of analytic risk determination (e.g., in probabilistic Safety Analysis (PSA) or Human Reliability Analysis (HRA)). A further example of these strategies of safety management is the empirical determination of risks through evaluation of operating experience (feedback control, e.g., epemiological studies, accident analysis) and, derived from this, identification of the system's weak points in terms of safety. Insights derived from the application of these control principles can serve to develop specific means of intervention. These will tend to be closely oriented to the results obtained with the control method and may consist in, e.g., trainings or measures of organisation development. Independent of this, it will also be possible to identify long-term measures for preventing safety-relevant occurrences (e.g., organisational learning, safety-mindedness). The above-named strategies of safety management (control, intervention, prevention) provide a fertile basis for psychological studies in fields such as the physiology and psychology of perception (information processing), cognitive, psychology (thought and action), social psychology (division of labour, norms), paedagogic psychology (training), or organisational and environmental psychology (safety-mindedness, leadership, environmental influences). (orig./DG) [de

Occupational health hazards in mining: an overview

Energy Technology Data Exchange (ETDEWEB)

Donoghue, A.M. [Alcoa World Alumina Australia, Perth, WA (Australia)

2004-08-01

This review article outlines the physical, chemical, biological, ergonomic and psychosocial occupational health hazards of mining and associated metallurgical processes. Mining remains an important industrial sector in many parts of the world and although substantial progress has been made in the control of occupational health hazards, there remains room for further risk reduction. This applies particularly to traumatic injury hazards, ergonomic hazards and noise. Vigilance is also required to ensure exposures to coal dust and crystalline silica remain effectively controlled.

Ground-Level Ozone Following Astrophysical Ionizing Radiation Events: An Additional Biological Hazard?

Science.gov (United States)

Thomas, Brian C; Goracke, Byron D

2016-01-01

Astrophysical ionizing radiation events such as supernovae, gamma-ray bursts, and solar proton events have been recognized as a potential threat to life on Earth, primarily through depletion of stratospheric ozone and subsequent increase in solar UV radiation at Earth's surface and in the upper levels of the ocean. Other work has also considered the potential impact of nitric acid rainout, concluding that no significant threat is likely. Not yet studied to date is the potential impact of ozone produced in the lower atmosphere following an ionizing radiation event. Ozone is a known irritant to organisms on land and in water and therefore may be a significant additional hazard. Using previously completed atmospheric chemistry modeling, we examined the amount of ozone produced in the lower atmosphere for the case of a gamma-ray burst and found that the values are too small to pose a significant additional threat to the biosphere. These results may be extended to other ionizing radiation events, including supernovae and extreme solar proton events.

Fuzzy Cognitive Maps for Glacier Hazards Assessment: Application to Predicting the Potential for Glacier Lake Outbursts

Science.gov (United States)

Furfaro, R.; Kargel, J. S.; Fink, W.; Bishop, M. P.

2010-12-01

Glaciers and ice sheets are among the largest unstable parts of the solid Earth. Generally, glaciers are devoid of resources (other than water), are dangerous, are unstable and no infrastructure is normally built directly on their surfaces. Areas down valley from large alpine glaciers are also commonly unstable due to landslide potential of moraines, debris flows, snow avalanches, outburst floods from glacier lakes, and other dynamical alpine processes; yet there exists much development and human occupation of some disaster-prone areas. Satellite remote sensing can be extremely effective in providing cost-effective and time- critical information. Space-based imagery can be used to monitor glacier outlines and their lakes, including processes such as iceberg calving and debris accumulation, as well as changing thicknesses and flow speeds. Such images can also be used to make preliminary identifications of specific hazardous spots and allows preliminary assessment of possible modes of future disaster occurrence. Autonomous assessment of glacier conditions and their potential for hazards would present a major advance and permit systematized analysis of more data than humans can assess. This technical leap will require the design and implementation of Artificial Intelligence (AI) algorithms specifically designed to mimic glacier experts’ reasoning. Here, we introduce the theory of Fuzzy Cognitive Maps (FCM) as an AI tool for predicting and assessing natural hazards in alpine glacier environments. FCM techniques are employed to represent expert knowledge of glaciers physical processes. A cognitive model embedded in a fuzzy logic framework is constructed via the synergistic interaction between glaciologists and AI experts. To verify the effectiveness of the proposed AI methodology as applied to predicting hazards in glacier environments, we designed and implemented a FCM that addresses the challenging problem of autonomously assessing the Glacier Lake Outburst Flow

A perspective on dose limits and biological effects of radiation on the foetus

International Nuclear Information System (INIS)

Myers, D.K.; Gordon, K.

1992-01-01

The potential biological effects of radiation doses to pregnant workers consistent with Canadian regulations and ICRP recommendations are reviewed. These hazards are in general very small compared to the normal hazards associated with human development. Potential carcinogenic effects may well be the major biological problem associated with foetal exposures. Radiation hazards to the embryo are essentially zero for exposures occurring during the first four weeks after conception. The new ICRP recommendations on exposures of pregnant women suggest a number of problems to be solved. These include (a) improvements in current methods of measuring both external radiation doses and intakes of certain radionuclides in Canada, (b) further research on the metabolism of radionuclides in pregnant women, including concentrations of certain radionuclides in foetal/embryonic tissues and also in adjacent tissues of the mother; and (c) socio-economic problems that may be involved in the implementation of the recommendations on exposures of pregnant workers, particularly in small facilities such as nuclear medicine departments in hospitals. (Author) 3 tabs., 21 refs

Analysis of potential hazards associated with 241Am loaded resins from nitrate media

International Nuclear Information System (INIS)

Schulte, Louis D.; Rubin, Jim; Fife, Keith William; Ricketts, Thomas Edgar; Tappan, Bryce C.; Chavez, David E.

2016-01-01

LANL has been contacted to provide possible assistance in safe disposition of a number of 241 Am-bearing materials associated with local industrial operations. Among the materials are ion exchange resins which have been in contact with 241 Am and nitric acid, and which might have potential for exothermic reaction. The purpose of this paper is to analyze and define the resin forms and quantities to the extent possible from available data to allow better bounding of the potential reactivity hazard of the resin materials. An additional purpose is to recommend handling procedures to minimize the probability of an uncontrolled exothermic reaction.

Technical Guidance for Hazardous Analysis, Emergency Planning for Extremely Hazardous Substances

Science.gov (United States)

This current guide supplements NRT-1 by providing technical assistance to LEPCs to assess the lethal hazards related to potential airborne releases of extremely hazardous substances (EHSs) as designated under Section 302 of Title Ill of SARA.

Technologies to remediate hazardous waste sites

International Nuclear Information System (INIS)

Falco, J.W.

1990-03-01

Technologies to remediate hazardous wastes must be matched with the properties of the hazardous materials to be treated, the environment in which the wastes are imbedded, and the desired extent of remediation. Many promising technologies are being developed, including biological treatment, immobilization techniques, and in situ methods. Many of these new technologies are being applied to remediate sites. The management and disposal of hazardous wastes is changing because of federal and state legislation as well as public concern. Future waste management systems will emphasize the substitution of alternatives for the use of hazardous materials and process waste recycling. Onsite treatment will also become more frequently adopted. 5 refs., 7 figs

In situ assessment of genotoxic hazards of environmental pollution.

Science.gov (United States)

Sandhu, S S; Lower, W R

1989-01-01

The potential impact of the environmental pollutants on human health can be evaluated by the laboratory analysis of the environmental samples or by the measurement of the biological effects on indigenous populations and/or specific test organisms placed in the environment to be monitored. A canary in a cage, used by 19th century miners as a biological indicator for rising levels of toxic gases, is a classical example of in situ hazard identification. The induced toxic effects are often the result of synergistic and antagonistic interactions among various physical and chemical factors that are difficult to reproduce in the laboratory. Therefore, conceivably the biological effects measured on or near the impacted site have greater relevancy for hazard assessment to man than from the data derived from the environmental samples analyzed in the lab. The organisms most commonly employed for the assessment of mutagenicity under real-world conditions are: (1) flowering plants, (2) wild and captive mammals, and (3) aquatic vertebrates. Plant species such as Tradescantia paludosa, Zea mays, and Osmunda regalis have been used for monitoring ambient air quality around several major industrial cities in the U.S.A., nuclear power plants, and industrial waste sites, and also for the assessment of potential health effects of municipal sewage sludges. Domestic animals such as dogs can be used as sentinels to provide information on the effects of contaminants in the environment and have been used to a limited extent to evaluate the environmental influences on the occurrence of breast cancer and osteosarcoma. Cytogenetic analysis from feral and wild animals has been employed for assessing the health hazards and prioritizing the clean-up efforts at hazardous waste sites. Aquatic animals have been used more often than terrestrial animals or plants to identify and characterize the genotoxic effects of environmental pollution. Since 1970, a number of studies has been reported on the

Potential for widespread application of biological control of stored-product pests

DEFF Research Database (Denmark)

Hansen, Lise Stengaard

2007-01-01

Biological control of stored product pests has substantial potential in Europe". This is essentially the conclusion of the activities of a European working group funded by the COST system, an intergovernmental networking system. Working group 4 of COST action 842 (2000-2005) focussed on biologica...... for these situations will contribute to ensuring that stored food products are protected from insect and mite pests using techniques that are safe for consumers, workers and the environment.......Biological control of stored product pests has substantial potential in Europe". This is essentially the conclusion of the activities of a European working group funded by the COST system, an intergovernmental networking system. Working group 4 of COST action 842 (2000-2005) focussed on biological...

Serious Adverse Events Associated With Using Biological Agents To Treat Rheumatic Diseases

DEFF Research Database (Denmark)

Tarp, Simon; Tarp, Ulrik; Andersen, Lis S

Background/Purpose: Clinical guidelines are needed to help clinicians provide optimal medical treatment and advise patients about the potential hazards associated with certain drugs. Our objective was to compare the number of serious adverse events (SAEs) for the biologics available for inflammat...

Polymer degradation and ultrafine particles - Potential inhalation hazards for astronauts

Science.gov (United States)

Ferin, J.; Oberdoerster, G.

1992-01-01

To test the hypothesis that exposure to ultrafine particles results in an increased interstiatilization of the particles which is accompanied by an acute pathological inflammation, rats were exposed to titanium dioxide (TiO2) particles by intratracheal instillation and by inhalation. Both acute intratracheal instillation and subchronic inhalation studies on rats show that ultrafine TiO2 particles access the pulmonary interstitium to a larger extent than fine particles and that they elicit an inflammatory response as indicated by PMN increase in lavaged cells. The release of ultrafine particles into the air of an enclosed environment from a thermodegradation event or from other sources is a potential hazard for astronauts. Knowing the mechanisms of action is a prerequisite for technical or medical countermeasures.

Comments on Potential Geologic and Seismic Hazards Affecting Proposed Liquefied Natural Gas Site in Santa Monica Bay, California

Science.gov (United States)

Ross, Stephanie L.; Lee, Homa J.; Parsons, Tom E.; Beyer, Larry A.; Boore, David M.; Conrad, James E.; Edwards, Brian D.; Fisher, Michael A.; Frankel, Arthur D.; Geist, Eric L.; Hudnut, Kenneth W.; Hough, Susan E.; Kayen, Robert E.; Lorenson, T.D.; Luco, Nicolas; McCrory, Patricia A.; McGann, Mary; Nathenson, Manuel; Nolan, Michael; Petersen, Mark D.; Ponti, Daniel J.; Powell, Charles L.; Ryan, Holly F.; Tinsley, John C.; Wills, Chris J.; Wong, Florence L.; Xu, Jingping

2008-01-01

In a letter to the U.S. Geological Survey (USGS) dated March 25, 2008, Representative Jane Harman (California 36th district) requested advice on geologic hazards that should be considered in the review of a proposed liquefied natural gas (LNG) facility off the California coast in Santa Monica Bay. In 2004, the USGS responded to a similar request from Representative Lois Capps, regarding two proposed LNG facilities offshore Ventura County, Calif., with a report summarizing potential geologic and seismic hazards (Ross and others, 2004). The proposed LNG Deepwater Port (DWP) facility includes single point moorings (SPMs) and 35 miles of underwater pipelines. The DWP submersible buoys, manifolds, and risers would be situated on the floor of the southern Santa Monica Basin, in 3,000 feet of water, about 23 miles offshore of the Palos Verdes Peninsula. Twin 24-inch diameter pipelines would extend northeastward from the buoys across the basin floor, up the basin slope and across the continental shelf, skirting north around the Santa Monica submarine canyon. Figure 1 provides locations of the project and geologic features. Acronyms are defined in table 1. This facility is being proposed in a region of known geologic hazards that arise from both the potential for strong earthquakes and geologic processes related to sediment transport and accumulation in the offshore environment. The probability of a damaging earthquake (considered here as magnitude 6.5 or greater) in the next 30 years within about 30 miles (50 km) of the proposed pipeline ranges from 16% at the pipeline's offshore end to 48% where it nears land (Petersen, 2008). Earthquakes of this magnitude are capable of producing strong shaking, surface fault offsets, liquefaction phenomena, landslides, underwater turbidity currents and debris flow avalanches, and tsunamis. As part of the DWP license application for the Woodside Natural Gas proposal in Santa Monica Bay (known as the OceanWay Secure Energy Project), Fugro

Site-specific seismic probabilistic tsunami hazard analysis: performances and potential applications

Science.gov (United States)

Tonini, Roberto; Volpe, Manuela; Lorito, Stefano; Selva, Jacopo; Orefice, Simone; Graziani, Laura; Brizuela, Beatriz; Smedile, Alessandra; Romano, Fabrizio; De Martini, Paolo Marco; Maramai, Alessandra; Piatanesi, Alessio; Pantosti, Daniela

2017-04-01

Seismic Probabilistic Tsunami Hazard Analysis (SPTHA) provides probabilities to exceed different thresholds of tsunami hazard intensity, at a specific site or region and in a given time span, for tsunamis caused by seismic sources. Results obtained by SPTHA (i.e., probabilistic hazard curves and inundation maps) represent a very important input to risk analyses and land use planning. However, the large variability of source parameters implies the definition of a huge number of potential tsunami scenarios, whose omission could lead to a biased analysis. Moreover, tsunami propagation from source to target requires the use of very expensive numerical simulations. At regional scale, the computational cost can be reduced using assumptions on the tsunami modeling (i.e., neglecting non-linear effects, using coarse topo-bathymetric meshes, empirically extrapolating maximum wave heights on the coast). On the other hand, moving to local scale, a much higher resolution is required and such assumptions drop out, since detailed inundation maps require significantly greater computational resources. In this work we apply a multi-step method to perform a site-specific SPTHA which can be summarized in the following steps: i) to perform a regional hazard assessment to account for both the aleatory and epistemic uncertainties of the seismic source, by combining the use of an event tree and an ensemble modeling technique; ii) to apply a filtering procedure which use a cluster analysis to define a significantly reduced number of representative scenarios contributing to the hazard of a specific target site; iii) to perform high resolution numerical simulations only for these representative scenarios and for a subset of near field sources placed in very shallow waters and/or whose coseismic displacements induce ground uplift or subsidence at the target. The method is applied to three target areas in the Mediterranean located around the cities of Milazzo (Italy), Thessaloniki (Greece) and

Lead dust in broken hill homes--a potential hazard for young children?

Science.gov (United States)

Boreland, F; Lyle, D M; Wlodarczyk, J; Balding, W A; Reddan, S

2002-01-01

To determine the potential hazard posed by indoor lead dust to young children in Broken Hill, a silver-lead-zinc mining town in outback Australia, and the degree to which lead flux is influenced by factors such as geographical location, house construction type and condition. 116 homes were selected and 93 (80%) studied from 10 localities in Broken Hill during the spring of 1995. Lead flux was measured using 85 mm diameter polystyrene petri dishes. Dishes were placed in four rooms of each house to collect dust over a six-to-eight-week period. Data on the location, condition and construction type of each house were recorded. Multiple linear regression was used to determine predictors of lead flux. Flux data were log transformed for the analysis. Average household lead flux varied nearly seven-fold across districts from a low of 166 (distant from the mines), to a high of 1,104 microg/m2/30-day period (adjacent to the mines). Houses that were 'adequately sealed' had 2.9 times the lead flux, and 'poorly sealed' houses 4.3 times the flux, of 'very well sealed' houses. Construction material did not significantly affect these flux levels, and no statistically significant interactions were found between house condition and location or house type. Many Broken Hill homes have high levels of lead flux that pose a potential risk to young children. Quantification of this hazard provides useful information for the community that can help focus efforts on actions required to minimise lead dust in the home. Household dust is a potential source of lead for young children in at-risk communities. Information on lead flux in homes can assist these communities and public health agencies to better understand and deal more effectively with the problem.

Biologically controlled minerals as potential indicators of life

Science.gov (United States)

Schwartz, D. E.; Mancinelli, R. L.; Kaneshiro, E.

1991-01-01

Minerals can be produced and deposited either by abiotic or biologic means. Regardless of their origin, mineral crystals reflect the environment conditions (e.g., temperature, pressure, chemical composition, and redox potential) present during crystal formation. Biologically-produced mineral crystals are grown or reworked under the control of their host organism and reflect an environment different from the abiotic environment. In addition, minerals of either biologic or abiotic origin have great longevities. For these reasons, biologically produced minerals have been proposed as biomarkers. Biomarkers are key morphological, chemical, and isotopic signatures of living systems that can be used to determine if life processes have occurred. Studies of biologically controlled minerals produced by the protist, Paramecium tetraurelia, were initiated since techniques have already been developed to culture them and isolate their crystalline material, and methods are already in place to analyze this material. Two direct crystalline phases were identified. One phase, whose chemical composition is high in Mg, was identified as struvite. The second phase, whose chemical composition is high in Ca, has not been previously found occurring naturally and may be considered a newly discovered material. Analyses are underway to determine the characteristics of these minerals in order to compare them with characteristics of these minerals in order to compare them with characteristics of minerals formed abiotically, but with the same chemical composition.

Multivariate Models for Prediction of Human Skin Sensitization Hazard

Science.gov (United States)

Strickland, Judy; Zang, Qingda; Paris, Michael; Lehmann, David M.; Allen, David; Choksi, Neepa; Matheson, Joanna; Jacobs, Abigail; Casey, Warren; Kleinstreuer, Nicole

2016-01-01

One of ICCVAM’s top priorities is the development and evaluation of non-animal approaches to identify potential skin sensitizers. The complexity of biological events necessary to produce skin sensitization suggests that no single alternative method will replace the currently accepted animal tests. ICCVAM is evaluating an integrated approach to testing and assessment based on the adverse outcome pathway for skin sensitization that uses machine learning approaches to predict human skin sensitization hazard. We combined data from three in chemico or in vitro assays—the direct peptide reactivity assay (DPRA), human cell line activation test (h-CLAT), and KeratinoSens™ assay—six physicochemical properties, and an in silico read-across prediction of skin sensitization hazard into 12 variable groups. The variable groups were evaluated using two machine learning approaches, logistic regression (LR) and support vector machine (SVM), to predict human skin sensitization hazard. Models were trained on 72 substances and tested on an external set of 24 substances. The six models (three LR and three SVM) with the highest accuracy (92%) used: (1) DPRA, h-CLAT, and read-across; (2) DPRA, h-CLAT, read-across, and KeratinoSens; or (3) DPRA, h-CLAT, read-across, KeratinoSens, and log P. The models performed better at predicting human skin sensitization hazard than the murine local lymph node assay (accuracy = 88%), any of the alternative methods alone (accuracy = 63–79%), or test batteries combining data from the individual methods (accuracy = 75%). These results suggest that computational methods are promising tools to effectively identify potential human skin sensitizers without animal testing. PMID:27480324

Kinematics, mechanics, and potential earthquake hazards for faults in Pottawatomie County, Kansas, USA

Science.gov (United States)

Ohlmacher, G.C.; Berendsen, P.

2005-01-01

Many stable continental regions have subregions with poorly defined earthquake hazards. Analysis of minor structures (folds and faults) in these subregions can improve our understanding of the tectonics and earthquake hazards. Detailed structural mapping in Pottawatomie County has revealed a suite consisting of two uplifted blocks aligned along a northeast trend and surrounded by faults. The first uplift is located southwest of the second. The northwest and southeast sides of these uplifts are bounded by northeast-trending right-lateral faults. To the east, both uplifts are bounded by north-trending reverse faults, and the first uplift is bounded by a north-trending high-angle fault to the west. The structural suite occurs above a basement fault that is part of a series of north-northeast-trending faults that delineate the Humboldt Fault Zone of eastern Kansas, an integral part of the Midcontinent Rift System. The favored kinematic model is a contractional stepover (push-up) between echelon strike-slip faults. Mechanical modeling using the boundary element method supports the interpretation of the uplifts as contractional stepovers and indicates that an approximately east-northeast maximum compressive stress trajectory is responsible for the formation of the structural suite. This stress trajectory suggests potential activity during the Laramide Orogeny, which agrees with the age of kimberlite emplacement in adjacent Riley County. The current stress field in Kansas has a N85??W maximum compressive stress trajectory that could potentially produce earthquakes along the basement faults. Several epicenters of seismic events (

Elucidating the Potential Biological Impact of Cellulose Nanocrystals

Directory of Open Access Journals (Sweden)

Sandra Camarero-Espinosa

2016-07-01

Full Text Available Cellulose nanocrystals exhibit an interesting combination of mechanical properties and physical characteristics, which make them potentially useful for a wide range of consumer applications. However, as the usage of these bio-based nanofibers increases, a greater understanding of human exposure addressing their potential health issues should be gained. The aim of this perspective is to highlight how knowledge obtained from studying the biological impact of other nanomaterials can provide a basis for future research strategies to deduce the possible human health risks posed by cellulose nanocrystals.

The potential for biological structure determination with pulsed neutrons

International Nuclear Information System (INIS)

Wilson, C.C.

1994-01-01

The potential of pulsed neutron diffraction in structural determination of biological materials is discussed. The problems and potential solutions in this area are outlined, with reference to both current and future sources and instrumentation. The importance of developing instrumentation on pulsed sources in emphasized, with reference to the likelihood of future expansion in this area. The possibilities and limitations of single crystal, fiber and powder diffraction in this area are assessed

The potential for biological structure determination with pulsed neutrons

Energy Technology Data Exchange (ETDEWEB)

Wilson, C.C. [CLRC Rutherford Appleton Laboratory, Chilton Didcot Oxon (United Kingdom)

1994-12-31

The potential of pulsed neutron diffraction in structural determination of biological materials is discussed. The problems and potential solutions in this area are outlined, with reference to both current and future sources and instrumentation. The importance of developing instrumentation on pulsed sources in emphasized, with reference to the likelihood of future expansion in this area. The possibilities and limitations of single crystal, fiber and powder diffraction in this area are assessed.

Public-private provision of protection measures against natural hazards

Science.gov (United States)

Gruber, M.

2009-04-01

Natural hazards threaten human lives as well as economic values of a society. Due to an increasing population density, augmenting property holdings in congested areas as well as higher frequencies of catastrophic events, the damage potential associated with natural hazards is growing. In order to safeguard societal assets against this threat, active and passive protection measures can be established. While passive protection measures provide for this type of risk by means of thorough land use planning, active protection measures aim at improving safety through technical or biological protective systems and structures. However, these provisions are costly and need to be handled prudentially. In most European countries protection measures against natural hazards are provided by the public. Specific governmental funds have been set up for the establishment of preventive systems as well as for damage compensation payments after the occurrence of catastrophic events. Though, additional capital is urgently needed in order to facilitate the realisation of all necessary projects in this field and to provide for maximal safety. One potential solution for such financial deficiencies can be found in Public Private Partnerships (PPP). PPPs have been implemented as attractive concepts for the funding of diverse projects in the fields of e.g. road construction, municipal, health and social services. In principle, they could also provide alternative funding solutions for the establishment of crucial protective infrastructure in respect of natural hazards, adding private financial means to the currently available public funds. Thereby, the entire capacities for catastrophe funding could be enhanced. Beside PPPs, also alternative funding mechanisms such as the emission of catastrophe bonds, contingent credit lines or leasing arrangements may enhance available capacities for the financing of protection measures. This contribution discusses innovative solutions for the funding of

NanoRiskCat: a conceptual tool for categorization and communication of exposure potentials and hazards of nanomaterials in consumer products

Science.gov (United States)

Hansen, Steffen Foss; Jensen, Keld Alstrup; Baun, Anders

2014-01-01

The literature on nano(eco)toxicology is growing rapidly and has become increasingly difficult to interpret. We have developed a systematic tool called NanoRiskCat that can support companies and regulators in their first-tier assessment and communication on what they know about the hazard and exposure potential of consumer products containing engineered nanomaterials. The final outcome of NanoRiskCat is communicated in the form of a short-title describing the intended use and five colored dots. The first three dots refer to the qualitative exposure potential for professional end-users, consumers and the environment, whereas the last two refers to the hazard potential for humans and the environment. Each dot can be assigned one of four different colors, i.e. red, yellow, green, and gray indicating high, medium, low, and unknown, respectively. In this paper, we first introduce the criteria used to evaluate the exposure potential and the human and environmental hazards of specific uses of the nanoproduct. We then apply NanoRiskCat to eight different nanoproducts. The human and environmental exposure potential was found to be high (i.e., red) for many of the products due to direct application on skin and subsequent environmental release. In the NanoRiskCat evaluation, many of the nanomaterials achieve a red human and environmental hazard profile as there is compelling in vivo evidence to associate them with irreversible effects, e.g., carcinogenicity, respiratory, and cardiovascular effects, etc., in laboratory animals. A significant strength of NanoRiskCat is that it can be used even in cases where lack of data is prominent.

Mast cells: potential positive and negative roles in tumor biology.

Science.gov (United States)

Marichal, Thomas; Tsai, Mindy; Galli, Stephen J

2013-11-01

Mast cells are immune cells that reside in virtually all vascularized tissues. Upon activation by diverse mechanisms, mast cells can secrete a broad array of biologically active products that either are stored in the cytoplasmic granules of the cells (e.g., histamine, heparin, various proteases) or are produced de novo upon cell stimulation (e.g., prostaglandins, leukotrienes, cytokines, chemokines, and growth factors). Mast cells are best known for their effector functions during anaphylaxis and acute IgE-associated allergic reactions, but they also have been implicated in a wide variety of processes that maintain health or contribute to disease. There has been particular interest in the possible roles of mast cells in tumor biology. In vitro studies have shown that mast cells have the potential to influence many aspects of tumor biology, including tumor development, tumor-induced angiogenesis, and tissue remodeling, and the shaping of adaptive immune responses to tumors. Yet, the actual contributions of mast cells to tumor biology in vivo remain controversial. Here, we review some basic features of mast cell biology with a special emphasis on those relevant to their potential roles in tumors. We discuss how using in vivo tumor models in combination with models in which mast cell function can be modulated has implicated mast cells in the regulation of host responses to tumors. Finally, we summarize data from studies of human tumors that suggest either beneficial or detrimental roles for mast cells in tumors. ©2013 AACR.

Spatial variability and potential impacts of climate change on flood and debris flow hazard zone mapping and implications for risk management

Directory of Open Access Journals (Sweden)

H. Staffler

2008-06-01

Full Text Available The main goals of this study were to identify the alpine torrent catchments that are sensitive to climatic changes and to assess the robustness of the methods for the elaboration of flood and debris flow hazard zone maps to specific effects of climate changes. In this study, a procedure for the identification and localization of torrent catchments in which the climate scenarios will modify the hazard situation was developed. In two case studies, the impacts of a potential increase of precipitation intensities to the delimited hazard zones were studied.

The identification and localization of the torrent and river catchments, where unfavourable changes in the hazard situation occur, could eliminate speculative and unnecessary measures against the impacts of climate changes like a general enlargement of hazard zones or a general over dimensioning of protection structures for the whole territory. The results showed a high spatial variability of the sensitivity of catchments to climate changes. In sensitive catchments, the sediment management in alpine torrents will meet future challenges due to a higher rate for sediment removal from retention basins. The case studies showed a remarkable increase of the areas affected by floods and debris flow when considering possible future precipitation intensities in hazard mapping. But, the calculated increase in extent of future hazard zones lay within the uncertainty of the methods used today for the delimitation of the hazard zones. Thus, the consideration of the uncertainties laying in the methods for the elaboration of hazard zone maps in the torrent and river catchments sensitive to climate changes would provide a useful instrument for the consideration of potential future climate conditions. The study demonstrated that weak points in protection structures in future will become more important in risk management activities.

Prevention and control of hazards in seafood

DEFF Research Database (Denmark)

Huss, Hans Henrik; Reilly, A.; Embarek, Peter Karim Ben

2000-01-01

-harvest and are difficult or impossible to control by applying presently available preventive measures. In contrast, the hazards related to contamination, recontamination or survival of biological hazards during processing are well-defined and can be controlled by applying Good Manufacturing Practice (GMP), Good Hygiene......Seafood is high on the list of foods transmitting disease. However, the food safety issues are highly focussed and more than 80% of all seafood-borne outbreaks are related to biotoxins (ciguatoxin), scombrotoxin or the consumption of raw molluscan shellfish. The safety hazards in seafood production...

NanoRiskCat: a conceptual tool for categorization and communication of exposure potentials and hazards of nanomaterials in consumer products

DEFF Research Database (Denmark)

Hansen, Steffen Foss; Baun, Anders

2014-01-01

and exposure potential of consumer products containing engineered nanomaterials. The final outcome of NanoRiskCat is communicated in the form of a short-title describing the intended use and five colored dots. The first three dots refer to the qualitative exposure potential for professional end......-users, consumers and the environment, whereas the last two refers to the hazard potential for humans and the environment. Each dot can be assigned one of four different colors, i.e. red, yellow, green, and gray indicating high, medium, low, and unknown, respectively. In this paper, we first introduce the criteria...... used to evaluate the exposure potential and the human and environmental hazards of specific uses of the nanoproduct. We then apply NanoRiskCat to eight different nanoproducts. The human and environmental exposure potential was found to be high (i.e., red) for many of the products due to direct...

Modified hazard ranking system for sites with mixed radioactive and hazardous wastes. User manual

International Nuclear Information System (INIS)

Hawley, K.A.; Peloquin, R.A.; Stenner, R.D.

1986-04-01

This document describes both the original Hazard Ranking System and the modified Hazard Ranking System as they are to be used in evaluating the relative potential for uncontrolled hazardous substance facilities to cause human health or safety problems or ecological or environmental damage. Detailed instructions for using the mHRS/HRS computer code are provided, along with instructions for performing the calculations by hand. Uniform application of the ranking system will permit the DOE to identify those releases of hazardous substances that pose the greatest hazard to humans or the environment. However, the mHRS/HRS by itself cannot establish priorities for the allocation of funds for remedial action. The mHRS/HRS is a means for applying uniform technical judgment regarding the potential hazards presented by a facility relative to other facilities. It does not address the feasibility, desirability, or degree of cleanup required. Neither does it deal with the readiness or ability of a state to carry out such remedial action, as may be indicated, or to meet other conditions prescribed in CERCLA. 13 refs., 13 figs., 27 tabs

Modified hazard ranking system for sites with mixed radioactive and hazardous wastes. User manual.

Energy Technology Data Exchange (ETDEWEB)

Hawley, K.A.; Peloquin, R.A.; Stenner, R.D.

1986-04-01

This document describes both the original Hazard Ranking System and the modified Hazard Ranking System as they are to be used in evaluating the relative potential for uncontrolled hazardous substance facilities to cause human health or safety problems or ecological or environmental damage. Detailed instructions for using the mHRS/HRS computer code are provided, along with instructions for performing the calculations by hand. Uniform application of the ranking system will permit the DOE to identify those releases of hazardous substances that pose the greatest hazard to humans or the environment. However, the mHRS/HRS by itself cannot establish priorities for the allocation of funds for remedial action. The mHRS/HRS is a means for applying uniform technical judgment regarding the potential hazards presented by a facility relative to other facilities. It does not address the feasibility, desirability, or degree of cleanup required. Neither does it deal with the readiness or ability of a state to carry out such remedial action, as may be indicated, or to meet other conditions prescribed in CERCLA. 13 refs., 13 figs., 27 tabs.

Biogeosystem technique as a method to overcome the Biological and Environmental Hazards of modern Agricultural, Irrigational and Technological Activities

Science.gov (United States)

Kalinitchenko, Valery; Batukaev, Abdulmalik; Zinchenko, Vladimir; Zarmaev, Ali; Magomadov, Ali; Chernenko, Vladimir; Startsev, Viktor; Bakoev, Serojdin; Dikaev, Zaurbek

2014-05-01

Modern challenge for humanity is to replace the paradigm of nature use and overcome environmental hazards of agronomy, irrigation, industry, and other human activities in biosphere. It is utterly reasonable to stop dividing biosphere on shares - the human habitat and the environment. In the 21st century it is an outdated anthropocentrism. Contradicting himself to biosphere Humankind has the problems. The new paradigm of biosphere control by methods of Biogeosystem technique is on agenda of Humankind. Key directions of Biogeosystem technique. Tillage. Single rotary milling 20…30-50…60 sm soil layer optimizes the evolution and environment of soil, creates a favorable conditions for the rhizosphere, increases the biological productivity of biosphere by 30-50% compared to the standard agricultural practices for the period up to 40 years. Recycle material. Recycling of mineral and organic substances in soil layer of 20…30-50…60 sm in rotary milling soil processing provides wastes clean return to biosphere. Direct intrasoil substances synthesis. Environmentally friendly robot wasteless nanotechnology provides direct substances synthesis, including fertilizers, inside the soil. It eliminates the prerequisites of the wastes formation under standard industrial technologies. Selective substance's extraction from soil. Electrochemical robotic nanotechnology provides selective substances extraction from soil. The technology provides recovery, collection and subsequent safe industrial use of extracted substances out of landscape. Saving fresh water. An important task is to save fresh water in biosphere. Irrigation spends water 4-5 times more of biological requirements of plants, leads to degradation of soil and landscape. The intrasoil pulse continuous-discrete paradigm of irrigation is proposed. It provides the soil and landscape conservation, increases the biological productivity, save the fresh water up to 10-20 times. The subsurface soil rotary processing and

Preparing Synthetic Biology for the World

Directory of Open Access Journals (Sweden)

Gerd H.G. Moe-Behrens

2013-01-01

Full Text Available Synthetic Biology promises low-cost, exponentially scalable products and global health solutions in the form of self-replicating organisms, or living devices. As these promises are realized, proof-of-concept systems will gradually migrate from tightly regulated laboratory or industrial environments into private spaces as, for instance, probiotic health products, food, and even do-it-yourself bioengineered systems. What additional steps, if any, should be taken before releasing engineered self-replicating organisms into a broader user space? In this review, we explain how studies of genetically modified organisms lay groundwork for the future landscape of biosafety. Early in the design process, biological engineers are anticipating potential hazards and developing innovative tools to mitigate risk. Here, we survey lessons learned, ongoing efforts to engineer intrinsic biocontainment, and how different stakeholders in synthetic biology can act to accomplish best practices for biosafety.

Hydrothermal Liquefaction Treatment Hazard Analysis Report

Energy Technology Data Exchange (ETDEWEB)

Lowry, Peter P. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Wagner, Katie A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

2016-09-12

Hazard analyses were performed to evaluate the modular hydrothermal liquefaction treatment system. The hazard assessment process was performed in 2 stages. An initial assessment utilizing Hazard Identification and Preliminary Hazards Analysis (PHA) techniques identified areas with significant or unique hazards (process safety-related hazards) that fall outside of the normal operating envelope of PNNL and warranted additional analysis. The subsequent assessment was based on a qualitative What-If analysis. The analysis was augmented, as necessary, by additional quantitative analysis for scenarios involving a release of hazardous material or energy with the potential for affecting the public. The following selected hazardous scenarios received increased attention: •Scenarios involving a release of hazardous material or energy, controls were identified in the What-If analysis table that prevent the occurrence or mitigate the effects of the release. •Scenarios with significant consequences that could impact personnel outside the immediate operations area, quantitative analyses were performed to determine the potential magnitude of the scenario. The set of “critical controls” were identified for these scenarios (see Section 4) which prevent the occurrence or mitigate the effects of the release of events with significant consequences.

Proceedings of emerging technologies for hazardous waste management

International Nuclear Information System (INIS)

Tedder, D.W.

1992-01-01

This paper contains the proceedings of emergin technologies for hazardous waste management. Topics covered include: advanced transuranic waste managements; remediation of soil/water systems contaminated with nonaqueous pollutants; advances in molten salt oxidation; air treatment and protection; advanced waste minimization strategies; removal of hazardous materials from soils or groundwater; bioremediation of soils and sediment; innovation, monitoring, and asbestos; high-level liquid waste chemistry in the Hanford tanks; biological contributions to soil and groundwater remediation; soil treatment technologies; pollution prevention; incineration and vitrification; current technology; systematic design approaches to hazardous waste management; waste management and environmental restoration at Savannah River; soil washing and flushing for remediation of hazardous wastes

Accidents with potentially hazardous biological material among workers in hospital supporting services.

Science.gov (United States)

Canini, Silvia Rita Marin da Silva; Gir, Elucir; Machado, Alcyone Artiolli

2005-01-01

Descriptive study was carried out to characterize the occupational accidents involving potentially contaminated material among workers of hospital supporting services. The study reviewed records of workers involved in these accidents and attended at a specialized outpatient clinic of a large tertiary care hospital between January 1997 and October 2001. A total of 2814 workers from different professional categories were attended during this period. Of these, 147 (5.2%) belonged to the hospital supporting services and were the victims of 156 accidents, auxiliary cleaning personnel (80.2%), and over a third of the workers had not received any dose of hepatitis B vaccine (35.4%). Most accidents were due to sharp injuries (96.8%) caused by inadequately discarded hollow needles. Chemoprophylaxis for HIV was not indicated in only 23.1% of cases. We conclude that these workers are also exposed to the possibility of acquiring blood-borne pathogens and that periodical education programs are needed.

Natural hazards science strategy

Science.gov (United States)

Holmes, Robert R.; Jones, Lucile M.; Eidenshink, Jeffery C.; Godt, Jonathan W.; Kirby, Stephen H.; Love, Jeffrey J.; Neal, Christina A.; Plant, Nathaniel G.; Plunkett, Michael L.; Weaver, Craig S.; Wein, Anne; Perry, Suzanne C.

2012-01-01

The mission of the U.S. Geological Survey (USGS) in natural hazards is to develop and apply hazard science to help protect the safety, security, and economic well-being of the Nation. The costs and consequences of natural hazards can be enormous, and each year more people and infrastructure are at risk. USGS scientific research—founded on detailed observations and improved understanding of the responsible physical processes—can help to understand and reduce natural hazard risks and to make and effectively communicate reliable statements about hazard characteristics, such as frequency, magnitude, extent, onset, consequences, and where possible, the time of future events.To accomplish its broad hazard mission, the USGS maintains an expert workforce of scientists and technicians in the earth sciences, hydrology, biology, geography, social and behavioral sciences, and other fields, and engages cooperatively with numerous agencies, research institutions, and organizations in the public and private sectors, across the Nation and around the world. The scientific expertise required to accomplish the USGS mission in natural hazards includes a wide range of disciplines that this report refers to, in aggregate, as hazard science.In October 2010, the Natural Hazards Science Strategy Planning Team (H–SSPT) was charged with developing a long-term (10-year) Science Strategy for the USGS mission in natural hazards. This report fulfills that charge, with a document hereinafter referred to as the Strategy, to provide scientific observations, analyses, and research that are critical for the Nation to become more resilient to natural hazards. Science provides the information that decisionmakers need to determine whether risk management activities are worthwhile. Moreover, as the agency with the perspective of geologic time, the USGS is uniquely positioned to extend the collective experience of society to prepare for events outside current memory. The USGS has critical statutory

Relative Hazard and Risk Measure Calculation Methodology

International Nuclear Information System (INIS)

Stenner, Robert D.; Strenge, Dennis L.; Elder, Matthew S.; Andrews, William B.; Walton, Terry L.

2003-01-01

The RHRM equations, as represented in methodology and code presented in this report, are primarily a collection of key factors normally used in risk assessment that are relevant to understanding the hazards and risks associated with projected mitigation, cleanup, and risk management activities. The RHRM code has broad application potential. For example, it can be used to compare one mitigation, cleanup, or risk management activity with another, instead of just comparing it to just the fixed baseline. If the appropriate source term data are available, it can be used in its non-ratio form to estimate absolute values of the associated controlling hazards and risks. These estimated values of controlling hazards and risks can then be examined to help understand which mitigation, cleanup, or risk management activities are addressing the higher hazard conditions and risk reduction potential at a site. Graphics can be generated from these absolute controlling hazard and risk values to graphically compare these high hazard and risk reduction potential conditions. If the RHRM code is used in this manner, care must be taken to specifically define and qualify (e.g., identify which factors were considered and which ones tended to drive the hazard and risk estimates) the resultant absolute controlling hazard and risk values

Software safety hazard analysis

International Nuclear Information System (INIS)

Lawrence, J.D.

1996-02-01

Techniques for analyzing the safety and reliability of analog-based electronic protection systems that serve to mitigate hazards in process control systems have been developed over many years, and are reasonably well understood. An example is the protection system in a nuclear power plant. The extension of these techniques to systems which include digital computers is not well developed, and there is little consensus among software engineering experts and safety experts on how to analyze such systems. One possible technique is to extend hazard analysis to include digital computer-based systems. Software is frequently overlooked during system hazard analyses, but this is unacceptable when the software is in control of a potentially hazardous operation. In such cases, hazard analysis should be extended to fully cover the software. A method for performing software hazard analysis is proposed in this paper

Recommendations for sampling for prevention of hazards in civil defense. On analytics of chemical, biological and radioactive contaminations. Brief instruction for the CBRN (chemical, biological, radioactive, nuclear) sampling; Empfehlungen fuer die Probenahme zur Gefahrenabwehr im Bevoelkerungsschutz. Zur Analytik von chemischen, biologischen und radioaktiven Kontaminationen. Kurzanleitung fuer die CBRN-Probenahme

Energy Technology Data Exchange (ETDEWEB)

Bachmann, Udo; Biederbick, Walter; Derakshani, Nahid (and others)

2010-07-01

The recommendation for sampling for prevention of hazards in civil defense is describing the analytics of chemical, biological and radioactive contaminations and includes detail information on the sampling, protocol preparation and documentation procedures. The volume includes a separate brief instruction for the CBRN (chemical, biological, radioactive, nuclear) sampling.

Synthetic Biology and Human Health: Potential Applications for Spaceflight

Science.gov (United States)

Karouia, Fathi; Carr, Christopher; Cai, Yizhi; Chen, Y.; Grenon, Marlene; Larios-Sanz, Maia; Jones, Jeffrey A.; Santos, Orlando

2011-01-01

Human space travelers experience a unique environment that affects homeostasis and physiologic adaptation. Spaceflight-related changes have been reported in the musculo-skeletal, cardiovascular, neurovestibular, endocrine, and immune systems. The spacecraft environment further subjects the traveler to noise and gravitational forces, as well as airborne chemical, microbiological contaminants, and radiation exposure. As humans prepare for longer duration missions effective countermeasures must be developed, verified, and implemented to ensure mission success. Over the past ten years, synthetic biology has opened new avenues for research and development in areas such as biological control, biomaterials, sustainable energy production, bioremediation, and biomedical therapies. The latter in particular is of great interest to the implementation of long-duration human spaceflight capabilities. This article discusses the effects of spaceflight on humans, and reviews current capabilities and potential needs associated with the health of the astronauts where synthetic biology could play an important role in the pursuit of space exploration.

PENERAPAN SISTEM HAZARD ANALYSIS CRITICAL CONTROL POINT (HACCP PADA PROSES PEMBUATAN KERIPIK TEMPE

Directory of Open Access Journals (Sweden)

Rahmi Yuniarti

2015-06-01

Full Text Available Malang is one of the industrial centers of tempe chips. To maintain the quality and food safety, analysis is required to identify the hazards during the production process. This study was conducted to identify the hazards during the production process of tempe chips and provide recommendations for developing a HACCP system. The phases of production process of tempe chips are started from slice the tempe, move it to the kitchen, coat it with flour dough, fry it in the pan, drain it, package it, and then storage it. There are 3 types of potential hazards in terms of biological, physical, and chemical during the production process. With the CCP identification, there are three processes that have Critical Control Point. There are the process of slicing tempe, immersion of tempe into the flour mixture and draining. Recommendations for the development of HACCP systems include recommendations related to employee hygiene, supporting equipment, 5-S analysis, and the production layout.

Distribution of potentially hazardous phases in the subsurface at Yucca Mountain, Nevada

International Nuclear Information System (INIS)

Guthrie, G.D. Jr.; Bish, D.L.; Chipera, S.J.; Raymond, R. Jr.

1995-05-01

Drilling, trenching, excavation of the Exploratory Studies Facility, and other surface and underground-distributing activities have the potential to release minerals into the environment from tuffs at Yucca Mountain, Nevada. Some of these minerals may be potential respiratory health hazards. Therefore, an understanding of the distribution of the minerals that may potentially be liberated during site-characterization and operation of the potential repository is crucial to ensuring worker and public safety. Analysis of previously reported mineralogy of Yucca Mountain tuffs using data and criteria from the International Agency for Research on Cancer (IARC) suggests that the following minerals are of potential concern: quartz, cristobalite, tridymite, opal-CT, erionite, mordenite, and palygorskite. The authors have re-evaluated the three-dimensional mineral distribution at Yucca Mountain above the static water level both in bulk-rock samples and in fractures, using quantitative X-ray powder diffraction analysis. Erionite, mordenite, and palygorskite occur primarily in fractures; the crystalline-silica minerals, quartz, cristobalite, and tridymite are major bulk-rock phases. Erionite occurs in the altered zone just above the lower Topopah Spring Member vitrophyre, and an occurrence below the vitrophyre but above the Calico Hills has recently been identified. In this latter occurrence, erionite is present in the matrix at levels up to 35 wt%. Mordenite and palygorskite occur throughout the vadose zone nearly to the surface. Opal-CT is limited to zeolitic horizons

78 FR 60755 - Hazardous Materials: Enhanced Enforcement Procedures-Resumption of Transportation

Science.gov (United States)

2013-10-02

... material,'' we envisioned etiological agents, such as biological products, infectious substances, medical... accidents or incidents involving the transportation of hazardous material. In order to achieve a uniform... DEPARTMENT OF TRANSPORTATION Pipeline and Hazardous Materials Safety Administration 49 CFR Part...

EFSA BIOHAZ Panel (EFSA Panel on Biologicial Hazards), 2013. Scientific Opinion on the public health hazards to be covered by inspection of meat (solipeds)

DEFF Research Database (Denmark)

Hald, Tine; Baggesen, Dorte Lau

2013-01-01

A risk ranking process identified Trichinella spp. as the most relevant biological hazard in the context of meat inspection of domestic solipeds. Without a full and reliable soliped traceability system, it is considered that either testing all slaughtered solipeds for Trichinella spp., or inactiv......A risk ranking process identified Trichinella spp. as the most relevant biological hazard in the context of meat inspection of domestic solipeds. Without a full and reliable soliped traceability system, it is considered that either testing all slaughtered solipeds for Trichinella spp...... for chemical hazards should be more flexible and based on the risk of occurrence, taking into account Food Chain Information (FCI), covering the specific on-farm environmental conditions and individual animal treatments, and the ranking of chemical substances, which should be regularly updated and include new...

Section 112 hazardous air pollutants Clean Air Act Amendments of 1990; potential impact of fossil/NUC

International Nuclear Information System (INIS)

Cronmiller, R.E.

1990-01-01

Control of hazardous air pollutants under the Clean Air Act (CAA) goes back several decades. Section 112 of the 1970 CAA as amended in 1977 served as the national statutory basis for controlling hazardous air pollutants until the most recent 1990 Amendments. Following severe criticism of the effectiveness of the Act to address hazardous air pollutant issues and a pile of seemingly never ending lawsuits challenging the regulatory process, the U.S. Congress has substantially rewritten Section 112 in the 1990 CAA Amendments. Many provisions heretofore requiring findings or regulatory decisions by the Environmental Protection Agency (EPA) Administrator are now automatic in the sense that the decisions have already been made by the US Congress legislatively. Thus, the new Section 112 has eliminated many of the existing regulatory obstacles, or safeguards; this will likely result in sweeping new regulatory programs mandating extensive controls on many industrial activities. A much needed study program to address fossil fuel fired steam electric generating units' hazardous air emissions and to identify control alternatives to regulate these emissions, if regulation is required, was incorporated into new Section 112. Because of this study, the regulatory fate of these units under the new Section 112 remains highly uncertain. An extensive regulatory program addressing hazardous air pollutants of these utility units under Section 112 would dwarf electric utility costs associated with the new acid rain control program. First, this paper identifies major provisions of the old law and the resulting regulatory status for both coal and nuclear power facilities before addressing the new Section 112 under the 1990 CAA Amendments and potential implications for electric utilities specifically

Evaluation of the Potential of NASA Multi-satellite Precipitation Analysis in Global Landslide Hazard Assessment

Science.gov (United States)

Hong, Yang; Adler, Robert F.; Huffman, George J.

2007-01-01

Landslides are one of the most widespread natural hazards on Earth, responsible for thousands of deaths and billions of dollars in property damage every year. In the U.S. alone landslides occur in every state, causing an estimated $2 billion in damage and 25- 50 deaths each year. Annual average loss of life from landslide hazards in Japan is 170. The situation is much worse in developing countries and remote mountainous regions due to lack of financial resources and inadequate disaster management ability. Recently, a landslide buried an entire village on the Philippines Island of Leyte on Feb 17,2006, with at least 1800 reported deaths and only 3 houses left standing of the original 300. Intense storms with high-intensity , long-duration rainfall have great potential to trigger rapidly moving landslides, resulting in casualties and property damage across the world. In recent years, through the availability of remotely sensed datasets, it has become possible to conduct global-scale landslide hazard assessment. This paper evaluates the potential of the real-time NASA TRMM-based Multi-satellite Precipitation Analysis (TMPA) system to advance our understanding of and predictive ability for rainfall-triggered landslides. Early results show that the landslide occurrences are closely associated with the spatial patterns and temporal distribution of rainfall characteristics. Particularly, the number of landslide occurrences and the relative importance of rainfall in triggering landslides rely on the influence of rainfall attributes [e.g. rainfall climatology, antecedent rainfall accumulation, and intensity-duration of rainstorms). TMPA precipitation data are available in both real-time and post-real-time versions, which are useful to assess the location and timing of rainfall-triggered landslide hazards by monitoring landslide-prone areas while receiving heavy rainfall. For the purpose of identifying rainfall-triggered landslides, an empirical global rainfall intensity

Workplace Hazards Faced by Nursing Assistants in the United States: A Focused Literature Review.

Science.gov (United States)

Walton, AnnMarie Lee; Rogers, Bonnie

2017-05-19

Nursing assistants (NAs) make up a large share of the healthcare provider workforce and their numbers are expected to grow. NAs are predominantly women who earn a low wage and report financial, work, and family demands. Working as a NA is hazardous; this manuscript specifically examines the biological/infectious, chemical, enviromechanical, physical and psychosocial hazards that appear in the literature to date. A focused search strategy was used to review literature about hazards that fell into each of the five aforementioned domains. While some hazards that were documented were clear, such as exposure to influenza because of close contact with patients (biological/infectious), or exposure to hazardous drugs (chemical), literature was limited. The majority of the literature we reviewed fell into the domain of psychosocial hazards and centered on stress from workplace organization issues (such as mandatory overtime, lack of managerial support, and feeling rushed). More research is needed to understand which hazards NAs identify as most concerning and tailored interventions are needed for risk mitigation.

Actinides: why are they important biologically

International Nuclear Information System (INIS)

Durbin, P.W.

1978-01-01

The following topics are discussed: actinide elements in energy systems; biological hazards of the actinides; radiation protection standards; and purposes of actinide biological research with regard to toxicity, metabolism, and therapeutic regimens

Biological toxicity evaluation of Hanford Site waste grouts

International Nuclear Information System (INIS)

Rebagay, T.V. Dodd, D.A.; Voogd, J.A.

1992-10-01

Liquid wastes containing radioactive, hazardous, and regulated chemicals have been generated throughout the 50 years of operation of the Hanford Site of the US Department of Energy near Richland, Washington. These wastes are currently stored onsite in single- and double-shell carbon steel tanks. To effectively handle and treat these wastes, their degree of toxicity must be determined. The disposal of the low-level radioactive liquid portion of the wastes involves mixing the wastes with pozzolanic blends to form grout. Potential environmental hazards posed by grouts are largely unknown. Biological evaluation of grout toxicity is needed to provide information on the potential risks of animal and plant exposure to the grouts. The fish, rat, and Microtox toxicity tests described herein indicate that the grouts formed from Formulations I and 2 are nonhazardous and nondangerous. Using the Microtox solid-phase protocol, both soluble and insoluble organic and inorganic toxicants in the grouts can be detected. This protocol may be used for rapid screening of environmental pollutants and toxicants

Analysis of potential hazards associated with ²⁴¹Am loaded resins from nitrate media

Energy Technology Data Exchange (ETDEWEB)

Schulte, Louis D. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Rubin, Jim [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Fife, Keith William [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Ricketts, Thomas Edgar [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Tappan, Bryce C. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Chavez, David E. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

2016-02-19

LANL has been contacted to provide possible assistance in safe disposition of a number of ²⁴¹Am-bearing materials associated with local industrial operations. Among the materials are ion exchange resins which have been in contact with ²⁴¹Am and nitric acid, and which might have potential for exothermic reaction. The purpose of this paper is to analyze and define the resin forms and quantities to the extent possible from available data to allow better bounding of the potential reactivity hazard of the resin materials. An additional purpose is to recommend handling procedures to minimize the probability of an uncontrolled exothermic reaction.

Identification of Aircraft Hazards

International Nuclear Information System (INIS)

K. Ashley

2006-01-01

Aircraft hazards were determined to be potentially applicable to a repository at Yucca Mountain in ''Monitored Geological Repository External Events Hazards Screening Analysis'' (BSC 2005 [DIRS 174235], Section 6.4.1). That determination was conservatively based upon limited knowledge of flight data in the area of concern and upon crash data for aircraft of the type flying near Yucca Mountain. The purpose of this report is to identify specific aircraft hazards that may be applicable to a monitored geologic repository (MGR) at Yucca Mountain, using NUREG-0800, ''Standard Review Plan for the Review of Safety Analysis Reports for Nuclear Power Plants'' (NRC 1987 [DIRS 103124], Section 3.5.1.6), as guidance for the inclusion or exclusion of identified aircraft hazards. The intended use of this report is to provide inputs for further screening and analysis of identified aircraft hazards based upon the criteria that apply to Category 1 and Category 2 event sequence analyses as defined in 10 CFR 63.2 [DIRS 176544] (Section 4). The scope of this report includes the evaluation of military, private, and commercial use of airspace in the 100-mile regional setting of the repository at Yucca Mountain with the potential for reducing the regional setting to a more manageable size after consideration of applicable screening criteria (Section 7)

Radiation biology for the non-biologist

International Nuclear Information System (INIS)

Myers, D.K.

1978-06-01

This colloquium introduces some of the general concepts used in cell biology and in the study of the effects of ionizing radiation on living organisms. The present research activities in radiation biology in the Biology Branch at the Chalk River Nuclear Laboratories cover a broad range of interests in the entire chain of events by which the initial radiation-induced changes in the living cell are translated into significant biological effects, including the eventual production of cancers and hereditary defects. The main theme of these research activities is an understanding of the mechanisms by which radiation damage to DNA (the carrier of hereditary information in all living organisms) can be actively repaired by the living cell. Advances in our understanding of these processes have broad implications for other areas of biology but also bear directly on the assessment of the biological hazards of ionizing radiation. The colloquium concludes with a brief discussion of the hazards of low-level radiation. (author)

Magnetic nanoparticles as potential candidates for biomedical and biological applications.

Science.gov (United States)

Zeinali Sehrig, Fatemeh; Majidi, Sima; Nikzamir, Nasrin; Nikzamir, Nasim; Nikzamir, Mohammad; Akbarzadeh, Abolfazl

2016-05-01

Magnetic iron oxide nanoparticles have become the main candidates for biomedical and biological applications, and the application of small iron oxide nanoparticles in in vitro diagnostics has been practiced for about half a century. Magnetic nanoparticles (MNPs), in combination with an external magnetic field and/or magnetizable grafts, allow the delivery of particles to the chosen target area, fix them at the local site while the medication is released, and act locally. In this review, we focus mostly on the potential use of MNPs for biomedical and biotechnological applications, and the improvements made in using these nanoparticles (NPs) in biological applications.

Estimation of radiation hazard of global 85Kr

International Nuclear Information System (INIS)

Vasilenko, I.Ya.; Moskalev, Yu.I.; Istomina, A.G.

1979-01-01

The data on sources and levels of the 85 Kr biosphere contamination are presented on the basis of generalization and analysis of literature. The potential irradiation doses for people are calculated and the biological estimation of the hazard of 85 Kr accumulation in the atmosphere up to 2050 is given taking into account the prospects for development of nuclear power engineering. The basis of the estimation is the radionuclide blastomogeneous and genetic effect. The conclusion is made that the prospects for development of nuclear power engineering do not lead to any sufficient increase in the number of malignant tumors and genetic abnormalities caused by 85 Kr radiation comparing with their natural frequency

Seismic Adequacy Review of PC012 SCEs that are Potential Seismic Hazards with PC3 SCEs - CVD Facility

International Nuclear Information System (INIS)

OCOMA, E.C.

1999-01-01

This document provides seismic adequacy review of PCO12 Systems, Components L Equipment anchorage that are potential seismic interaction hazards with PC3 SCEs during a Design Basis Earthquake. The PCO12 items are identified in the Safety Equipment List as 3/1 SCEs

Exploiting biological activities of brown seaweed Ecklonia cava for potential industrial applications: a review.

Science.gov (United States)

Wijesinghe, W A J P; Jeon, You-Jin

2012-03-01

Seaweeds are rich in vitamins, minerals, dietary fibres, proteins, polysaccharides and various functional polyphenols. Many researchers have focused on brown algae as a potential source of bioactive materials in the past few decades. Ecklonia cava is a brown seaweed that is abundant in the subtidal regions of Jeju Island in the Republic of Korea. This seaweed attracted extensive interest due to its multiple biological activities. E. cava has been identified as a potential producer of wide spectrum of natural substances such as carotenoids, fucoidans and phlorotannins showing different biological activities in vital industrial applications including pharmaceutical, nutraceutical, cosmeceutical and functional food. This review focuses on biological activities of the brown seaweed E. cava based on latest research results, including antioxidant, anticoagulative, antimicrobial, antihuman immunodeficiency virus, anti-inflammatory, immunomodulatory, antimutagenic, antitumour and anticancer effects. The facts summarized here may provide novel insights into the functions of E. cava and its derivatives and potentially enable their use as functional ingredients in potential industrial applications.

Recommendations for sampling for prevention of hazards in civil defense. On analytics of chemical, biological and radioactive contaminations. 2. ed.; Empfehlungen fuer die Probenahme zur Gefahrenabwehr im Bevoelkerungsschutz. Zur Analytik von chemischen, biologischen und radioaktiven Kontaminationen

Energy Technology Data Exchange (ETDEWEB)

Bachmann, Udo; Derakshani, Nahid; Drobig, Matthias; Koenig, Mario; Mentfewitz, Joachim; Prast, Hartmut; Uelpenich, Gerhard; Vidmayer, Marc; Wilbert, Stefan; Wolf, Manfred

2016-07-01

The recommendations for sampling for prevention of hazards in civil defense (analytics of chemical, biological and radioactive contaminations) cover the following topics: Requirements for sampling, description of the materials (chemical, biological and radioactive contaminated materials), decontamination, sample transport and protocol documents.

In situ vitrification - A potential remedial action technique for hazardous wastes

International Nuclear Information System (INIS)

Fitzpatrick, V.F.; Buelt, J.L.; Oma, K.H.; Timmerman, C.L.

1984-01-01

In situ vitrification (ISV) is an innovative technology being developed as a potential method for stabilizing transuranic (TRU) contaminated wastes in place. Although the process is being developed for TRU contaminated wastes, it is envisioned that the process could also be applied to hazardous chemical wastes. In situ vitrification (ISV) is the conversion of contaminated soil into a durable glass and crystalline wastes form through melting by joule heating. The technology for in situ vitrification is based upon electric melter technology developed at the Pacific Northwest Laboratory (PNL) for the immobilization of high-level nuclear waste. In situ vitrification was initially tested by researchers at PNL in August, 1980 (U.S. Patent 4,376,598). Since then, ISV has grown from a concept to an emerging technology through a series of 21 engineering-scale (laboratory) tests and 7 pilot-scale (field) tests. A large-scale system is currently being fabricated for testing. The program has been sponsored by the U.S. Department of Energy's (DOE) Richland Operations Office for potential application to Hanford TRU contaminated soil sites. A more detailed description outlining the power system design and the off-gas treatment system follows

Modern tornado design of nuclear and other potentially hazardous facilities

International Nuclear Information System (INIS)

Stevenson, J.D.; Zhao, Y.

1996-01-01

Tornado wind loads and other tornado phenomena, including tornado missiles and differential pressure effects, have not usually been considered in the design of conventional industrial, commercial, or residential facilities in the United States; however, tornado resistance has often become a design requirement for certain hazardous facilities, such as large nuclear power plants and nuclear materials and waste storage facilities, as well as large liquefied natural gas storage facilities. This article provides a review of current procedures for the design of hazardous industrial facilities to resist tornado effects. 23 refs., 19 figs., 13 tabs

Hazard screening application guide

International Nuclear Information System (INIS)

1992-06-01

The basic purpose of hazard screening is to group precesses, facilities, and proposed modifications according to the magnitude of their hazards so as to determine the need for and extent of follow on safety analysis. A hazard is defined as a material, energy source, or operation that has the potential to cause injury or illness in human beings. The purpose of this document is to give guidance and provide standard methods for performing hazard screening. Hazard screening is applied to new and existing facilities and processes as well as to proposed modifications to existing facilities and processes. The hazard screening process evaluates an identified hazards in terms of the effects on people, both on-site and off-site. The process uses bounding analyses with no credit given for mitigation of an accident with the exception of certain containers meeting DOT specifications. The process is restricted to human safety issues only. Environmental effects are addressed by the environmental program. Interfaces with environmental organizations will be established in order to share information

Hearing loss and potential hazards of metallic middle-ear implants in NMR-magnetic fields

International Nuclear Information System (INIS)

Huettenbrink, K.B.

1987-01-01

Concurrent with the expanding clinical applications of nuclear magnetic resonance (NMR) imaging, patients with metallic middle-ear implants will certainly be exposed to this strong magnetic field in the future. To determine potential hazards, associated with movements of steel- or Platinium stapes-prostheses, several tests were performed in a 0.5 tesla NMR unit and the induced forces were calculated. Although the commonly used paramagnetic steel-wire or platinium-alloys will not dislodge in vivo, ferromagnetic prostheses may present a hazardous risk. Prior to exposure to the magnetic field, information about the implanted material should therefore be obtained. A side-effect of the induced current flow is the attenuation of the sound-vibrations of the stapes prosthesis. This, 5-10 dB impairment of transmission develops only at a certain position of the patient's head, when the prosthesis vibrates perpendicularly to the magnetic field's Z-axis. Patients with a metallic prosthesis should be informed about this purely physical, harmless phenomenon prior to entering the NMR-cylinder. (orig.) [de

Relative Hazard Calculation Methodology

International Nuclear Information System (INIS)

DL Strenge; MK White; RD Stenner; WB Andrews

1999-01-01

The methodology presented in this document was developed to provide a means of calculating the RH ratios to use in developing useful graphic illustrations. The RH equation, as presented in this methodology, is primarily a collection of key factors relevant to understanding the hazards and risks associated with projected risk management activities. The RH equation has the potential for much broader application than generating risk profiles. For example, it can be used to compare one risk management activity with another, instead of just comparing it to a fixed baseline as was done for the risk profiles. If the appropriate source term data are available, it could be used in its non-ratio form to estimate absolute values of the associated hazards. These estimated values of hazard could then be examined to help understand which risk management activities are addressing the higher hazard conditions at a site. Graphics could be generated from these absolute hazard values to compare high-hazard conditions. If the RH equation is used in this manner, care must be taken to specifically define and qualify the estimated absolute hazard values (e.g., identify which factors were considered and which ones tended to drive the hazard estimation)

Sensors Provide Early Warning of Biological Threats

Science.gov (United States)

2009-01-01

Early Warning Inc. of Troy, New York, licensed powerful biosensor technology from Ames Research Center. Incorporating carbon nanotubes tipped with single strands of nucleic acid from waterborne pathogens, the sensor can detect even minute amounts of targeted, disease causing bacteria, viruses, and parasites. Early Warning features the NASA biosensor in its water analyzer, which can provide advance alert of potential biological hazards in water used for agriculture, food and beverages, showers, and at beaches and lakes -- within hours instead of the days required by conventional laboratory methods.

Hazard classification criteria for non-nuclear facilities

International Nuclear Information System (INIS)

Mahn, J.A.; Walker, S.A.

1997-01-01

Sandia National Laboratories' Integrated Risk Management Department has developed a process for establishing the appropriate hazard classification of a new facility or operation, and thus the level of rigor required for the associated authorization basis safety documentation. This process is referred to as the Preliminary Hazard Screen. DOE Order 5481.1B contains the following hazard classification for non-nuclear facilities: high--having the potential for onsite or offsite impacts to large numbers of persons or for major impacts to the environment; moderate--having the potential for considerable onsite impacts but only minor offsite impacts to people or the environment; low--having the potential for only minor onsite and negligible offsite impacts to people or the environment. It is apparent that the application of such generic criteria is more than likely to be fraught with subjective judgment. One way to remove the subjectivity is to define health and safety classification thresholds for specific hazards that are based on the magnitude of the hazard, rather than on a qualitative assessment of possible accident consequences. This paper presents the results of such an approach to establishing a readily usable set of non-nuclear facility hazard classifications

Prevalence of hazardous exposures in veterinary practice

Energy Technology Data Exchange (ETDEWEB)

Wiggins, P.; Schenker, M.B.; Green, R.; Samuels, S.

1989-01-01

All female graduates of a major U.S. veterinary school were surveyed by mailed questionnaire to obtain details of work practice and hazard exposure during the most recent year worked and during all pregnancies. Exposure questions were based on previously implicated occupational hazards which included anesthetic gases, radiation, zoonoses, prostaglandins, vaccines, physical trauma, and pesticides. The response rate was 86% (462/537). We found that practice type and pregnancy status were major determinants of hazard exposure within the veterinary profession. Small-animal practitioners reported the highest rates of exposure to anesthetic gas (94%), X-ray (90%), and pesticides (57%). Large-animal practitioners reported greater rates of trauma (64%) and potential exposure to prostaglandins (92%), Brucella abortus vaccine (23%), and carbon monoxide (18%). Potentially hazardous workplace practices or equipment were common. Forty-one percent of respondents who reported taking X-rays did not wear film badges, and 76% reported physically restraining animals for X-ray procedures. Twenty-seven percent of the respondents exposed to anesthetic gases worked at facilities which did not have waste anesthetic gas scavenging systems. Women who worked as veterinarians during a pregnancy attempted to reduce exposures to X-rays, insecticides, and other potentially hazardous exposures. Some potentially hazardous workplace exposures are common in veterinary practice, and measures to educate workers and to reduce these exposures should not await demonstration of adverse health effects.

Prevalence of hazardous exposures in veterinary practice

International Nuclear Information System (INIS)

Wiggins, P.; Schenker, M.B.; Green, R.; Samuels, S.

1989-01-01

All female graduates of a major U.S. veterinary school were surveyed by mailed questionnaire to obtain details of work practice and hazard exposure during the most recent year worked and during all pregnancies. Exposure questions were based on previously implicated occupational hazards which included anesthetic gases, radiation, zoonoses, prostaglandins, vaccines, physical trauma, and pesticides. The response rate was 86% (462/537). We found that practice type and pregnancy status were major determinants of hazard exposure within the veterinary profession. Small-animal practitioners reported the highest rates of exposure to anesthetic gas (94%), X-ray (90%), and pesticides (57%). Large-animal practitioners reported greater rates of trauma (64%) and potential exposure to prostaglandins (92%), Brucella abortus vaccine (23%), and carbon monoxide (18%). Potentially hazardous workplace practices or equipment were common. Forty-one percent of respondents who reported taking X-rays did not wear film badges, and 76% reported physically restraining animals for X-ray procedures. Twenty-seven percent of the respondents exposed to anesthetic gases worked at facilities which did not have waste anesthetic gas scavenging systems. Women who worked as veterinarians during a pregnancy attempted to reduce exposures to X-rays, insecticides, and other potentially hazardous exposures. Some potentially hazardous workplace exposures are common in veterinary practice, and measures to educate workers and to reduce these exposures should not await demonstration of adverse health effects

Offsite transportation hazards assessment

International Nuclear Information System (INIS)

Burnside, M.E.

1997-01-01

This report documents the emergency preparedness Hazards Assessment for the offsite transportation of hazardous material from the Hanford Site. The assessment is required by the US Department of Energy (DOE) Order 151.1. Offsite transportation accidents are categorized using the DOE system to assist communication within the DOE and assure that appropriate assistance is provided to the people in charge at the scene. The assistance will initially include information about the load and the potential hazards. Local authorities will use the information to protect the public following a transportation accident. This Hazards Assessment will focus on the material being transported from the Hanford Site. Shipments coming to Hanford are the responsibility of the shipper and the carrier and, therefore, are not included in this Hazards Assessment, unless the DOE elects to be the shipper of record

To the problem of biological risk

International Nuclear Information System (INIS)

Vasilenko, I.Ya.; Moskalev, Yu.I.

1977-01-01

Biological hazard of iodine-129 intake of the man organism is estimated. Data on the iodine-129 biological effect on men and animals are considered. Iodine-129 biological effect on a critical organ-man thyroid gland - as well as genetic danger of its intake by the man organism is also estimated

Creating biological nanomaterials using synthetic biology

International Nuclear Information System (INIS)

Rice, MaryJoe K; Ruder, Warren C

2014-01-01

Synthetic biology is a new discipline that combines science and engineering approaches to precisely control biological networks. These signaling networks are especially important in fields such as biomedicine and biochemical engineering. Additionally, biological networks can also be critical to the production of naturally occurring biological nanomaterials, and as a result, synthetic biology holds tremendous potential in creating new materials. This review introduces the field of synthetic biology, discusses how biological systems naturally produce materials, and then presents examples and strategies for incorporating synthetic biology approaches in the development of new materials. In particular, strategies for using synthetic biology to produce both organic and inorganic nanomaterials are discussed. Ultimately, synthetic biology holds the potential to dramatically impact biological materials science with significant potential applications in medical systems. (review)

Creating biological nanomaterials using synthetic biology.

Science.gov (United States)

Rice, MaryJoe K; Ruder, Warren C

2014-02-01

Synthetic biology is a new discipline that combines science and engineering approaches to precisely control biological networks. These signaling networks are especially important in fields such as biomedicine and biochemical engineering. Additionally, biological networks can also be critical to the production of naturally occurring biological nanomaterials, and as a result, synthetic biology holds tremendous potential in creating new materials. This review introduces the field of synthetic biology, discusses how biological systems naturally produce materials, and then presents examples and strategies for incorporating synthetic biology approaches in the development of new materials. In particular, strategies for using synthetic biology to produce both organic and inorganic nanomaterials are discussed. Ultimately, synthetic biology holds the potential to dramatically impact biological materials science with significant potential applications in medical systems.

MGR External Events Hazards Analysis

International Nuclear Information System (INIS)

Booth, L.

1999-01-01

The purpose and objective of this analysis is to apply an external events Hazards Analysis (HA) to the License Application Design Selection Enhanced Design Alternative 11 [(LADS EDA II design (Reference 8.32))]. The output of the HA is called a Hazards List (HL). This analysis supersedes the external hazards portion of Rev. 00 of the PHA (Reference 8.1). The PHA for internal events will also be updated to the LADS EDA II design but under a separate analysis. Like the PHA methodology, the HA methodology provides a systematic method to identify potential hazards during the 100-year Monitored Geologic Repository (MGR) operating period updated to reflect the EDA II design. The resulting events on the HL are candidates that may have potential radiological consequences as determined during Design Basis Events (DBEs) analyses. Therefore, the HL that results from this analysis will undergo further screening and analysis based on the criteria that apply during the performance of DBE analyses

Using fine-scale fuel measurements to assess wildland fuels, potential fire behavior and hazard mitigation treatments in the southeastern USA

International Nuclear Information System (INIS)

Ottmar, Roger D.; Blake, John I.; Crolly, William T.

2012-01-01

The inherent spatial and temporal heterogeneity of fuelbeds in forests of the southeastern United States may require fine scale fuel measurements for providing reliable fire hazard and fuel treatment effectiveness estimates. In a series of five papers, an intensive, fine scale fuel inventory from the Savanna River Site in the southeastern United States is used for building fuelbeds and mapping fire behavior potential, evaluating fuel treatment options for effectiveness, and providing a comparative analysis of landscape modeled fire behavior using three different data sources including the Fuel Characteristic Classification System, LANDFIRE, and the Southern Wildfire Risk Assessment. The research demonstrates that fine scale fuel measurements associated with fuel inventories repeated over time can be used to assess broad scale wildland fire potential and hazard mitigation treatment effectiveness in the southeastern USA and similar fire prone regions. Additional investigations will be needed to modify and improve these processes and capture the true potential of these fine scale data sets for fire and fuel management planning.

The Prevalence of Selected Potentially Hazardous Workplace Exposures in the US: Findings From the 2010 National Health Interview Survey

Science.gov (United States)

Calvert, Geoffrey M.; Luckhaupt, Sara E.; Sussell, Aaron; Dahlhamer, James M.; Ward, Brian W.

2015-01-01

Objective Assess the national prevalence of current workplace exposure to potential skin hazards, secondhand smoke (SHS), and outdoor work among various industry and occupation groups. Also, assess the national prevalence of chronic workplace exposure to vapors, gas, dust, and fumes (VGDF) among these groups. Methods Data were obtained from the 2010 National Health Interview Survey (NHIS). NHIS is a multistage probability sample survey of the civilian non-institutionalized population of the US. Prevalence rates and their variances were calculated using SUDAAN to account for the complex NHIS sample design. Results The data for 2010 were available for 17,524 adults who worked in the 12 months that preceded interview. The highest prevalence rates of hazardous workplace exposures were typically in agriculture, mining, and construction. The prevalence rate of frequent handling of or skin contact with chemicals, and of non-smokers frequently exposed to SHS at work was highest in mining and construction. Outdoor work was most common in agriculture (85%), construction (73%), and mining (65%). Finally, frequent occupational exposure to VGDF was most common among mining (67%), agriculture (53%), and construction workers (51%). Conclusion We identified industries and occupations with the highest prevalence of potentially hazardous workplace exposures, and provided targets for investigation and intervention activities. PMID:22821700

Workplace Hazards Faced by Nursing Assistants in the United States: A Focused Literature Review

Science.gov (United States)

Walton, AnnMarie Lee; Rogers, Bonnie

2017-01-01

Nursing assistants (NAs) make up a large share of the healthcare provider workforce and their numbers are expected to grow. NAs are predominantly women who earn a low wage and report financial, work, and family demands. Working as a NA is hazardous; this manuscript specifically examines the biological/infectious, chemical, enviromechanical, physical and psychosocial hazards that appear in the literature to date. A focused search strategy was used to review literature about hazards that fell into each of the five aforementioned domains. While some hazards that were documented were clear, such as exposure to influenza because of close contact with patients (biological/infectious), or exposure to hazardous drugs (chemical), literature was limited. The majority of the literature we reviewed fell into the domain of psychosocial hazards and centered on stress from workplace organization issues (such as mandatory overtime, lack of managerial support, and feeling rushed). More research is needed to understand which hazards NAs identify as most concerning and tailored interventions are needed for risk mitigation. PMID:28534859

Workplace Hazards Faced by Nursing Assistants in the United States: A Focused Literature Review

Directory of Open Access Journals (Sweden)

AnnMarie Lee Walton

2017-05-01

Full Text Available Nursing assistants (NAs make up a large share of the healthcare provider workforce and their numbers are expected to grow. NAs are predominantly women who earn a low wage and report financial, work, and family demands. Working as a NA is hazardous; this manuscript specifically examines the biological/infectious, chemical, enviromechanical, physical and psychosocial hazards that appear in the literature to date. A focused search strategy was used to review literature about hazards that fell into each of the five aforementioned domains. While some hazards that were documented were clear, such as exposure to influenza because of close contact with patients (biological/infectious, or exposure to hazardous drugs (chemical, literature was limited. The majority of the literature we reviewed fell into the domain of psychosocial hazards and centered on stress from workplace organization issues (such as mandatory overtime, lack of managerial support, and feeling rushed. More research is needed to understand which hazards NAs identify as most concerning and tailored interventions are needed for risk mitigation.

IDENTIFICATION OF AIRCRAFT HAZARDS

International Nuclear Information System (INIS)

K.L. Ashley

2005-01-01

Aircraft hazards were determined to be potentially applicable to a repository at Yucca Mountain in the ''Monitored Geological Repository External Events Hazards Screening Analysis'' (BSC 2004, Section 6.4.1). That determination was conservatively based on limited knowledge of flight data in the area of concern and on crash data for aircraft of the type flying near Yucca Mountain. The purpose of this report is to identify specific aircraft hazards that may be applicable to a Monitored Geologic Repository (MGR) at Yucca Mountain using NUREG-0800, ''Standard Review Plan for the Review of Safety Analysis Reports for Nuclear Power Plants'' (NRC 1987, Section 3.5.1.6), as guidance for the inclusion or exclusion of identified aircraft hazards. NUREG-0800 is being used here as a reference because some of the same considerations apply. The intended use of this report is to provide inputs for further screening and analysis of the identified aircraft hazards based on the criteria that apply to Category 1 and 2 event sequence analyses as defined in 10 CFR 63.2 (see Section 4). The scope of this technical report includes the evaluation of military, private, and commercial use of airspace in the 100-mile regional setting of the MGR at Yucca Mountain with the potential for reducing the regional setting to a more manageable size after consideration of applicable screening criteria (see Section 7)

Identification of Aircraft Hazards

Energy Technology Data Exchange (ETDEWEB)

K. Ashley

2006-12-08

Aircraft hazards were determined to be potentially applicable to a repository at Yucca Mountain in ''Monitored Geological Repository External Events Hazards Screening Analysis'' (BSC 2005 [DIRS 174235], Section 6.4.1). That determination was conservatively based upon limited knowledge of flight data in the area of concern and upon crash data for aircraft of the type flying near Yucca Mountain. The purpose of this report is to identify specific aircraft hazards that may be applicable to a monitored geologic repository (MGR) at Yucca Mountain, using NUREG-0800, ''Standard Review Plan for the Review of Safety Analysis Reports for Nuclear Power Plants'' (NRC 1987 [DIRS 103124], Section 3.5.1.6), as guidance for the inclusion or exclusion of identified aircraft hazards. The intended use of this report is to provide inputs for further screening and analysis of identified aircraft hazards based upon the criteria that apply to Category 1 and Category 2 event sequence analyses as defined in 10 CFR 63.2 [DIRS 176544] (Section 4). The scope of this report includes the evaluation of military, private, and commercial use of airspace in the 100-mile regional setting of the repository at Yucca Mountain with the potential for reducing the regional setting to a more manageable size after consideration of applicable screening criteria (Section 7).

Do field-free electromagnetic potentials play a role in biology?

Science.gov (United States)

Szasz, A; Vincze, G; Andocs, G; Szasz, O

2009-01-01

All bio-systems are imperfect dielectrics. Their general properties however cannot be described by conventional simple electrodynamics; the system is more complex. A central question in our present paper is centered on a controversial debate of the possible effect of the zero fields (only potentials exist). We show that the identical use of the "field-free," "curl-free," and "force-free" terminologies is incorrect, there have definitely different meanings. It is shown that the effective electro-dynamical parameters that describe and modify living systems are the potentials and not the fields. We discuss how the potentials have a role in biological processes even in field-free cases.

Plutonium Finishing Plant (PFP) hazards assessment

International Nuclear Information System (INIS)

Campbell, L.R.

1998-01-01

This report documents the hazards assessment for the Plutonium Finishing Plant (PFP) located on the US Department of Energy (DOE) Hanford Site. This hazards assessment was conducted to provide the emergency planning technical basis for the PFP. DOE Orders require an emergency planning hazards assessment for each facility that has the potential to reach or exceed the lowest level emergency classification

Biological potential of Stillingia oppositifolia

Directory of Open Access Journals (Sweden)

Betania Barros Cota

2011-02-01

Full Text Available Organic extracts from leaves and stems of Stillingia oppositifolia Baill. ex Müll. Arg., Euphorbiaceae, were screened for antifungal and cytotoxic properties. The extracts presented Minimum Inhibitory Concentration values around 250 µg.mL-1 against Candida krusei and Candida tropicalis, and around 63 µg.mL-1 for Paracoccidioides brasiliensis. They were tested on three human cell lines (UACC-62, MCF-7, and TK-10, disclosing GI50 values, (concentration able to inhibit 50% of the cell growth ranging from 50 to 100 µg.mL-1. Organic extract from stems furnished hexanic, dichloromethanic and aqueous phases after partition. Chromatographic fractionation of the hexanic soluble phase of the stems yielded aleuritolic acid 3-acetate, β-sitosterol, 3-epi-β-amyrin, β-amyrone and palmitic acid. These compounds showed antifungal and cytotoxic activities in the same range as the organic crude extract and low toxic effect against mononuclear cells obtained from human peripheral blood. This is the first report on chemical and biological potential of S. oppositifolia.

Evaluation of potential hazards presented by the nearby industrial environment and transportation routes

International Nuclear Information System (INIS)

1982-05-01

RFS or Regles Fondamentales de Surete (Basic Safety Rules) applicable to certain types of nuclear facilities lay down requirements with which compliance, for the type of facilities and within the scope of application covered by the RFS, is considered to be equivalent to compliance with technical French regulatory practice. The object of the RFS is to take advantage of standardization in the field of safety, while allowing for technical progress in that field. They are designed to enable the operating utility and contractors to know the rules pertaining to various subjects which are considered to be acceptable by the Service Central de Surete des Installations Nucleaires, or the SCSIN (Central Department for the Safety of Nuclear Facilities). These RFS should make safety analysis easier and lead to better understanding between experts and individuals concerned with the problems of nuclear safety. The SCSIN reserves the right to modify, when considered necessary, any RFS and specify, if need be, the terms under which a modification is deemed retroactive. The purpose of this RFS is to define methods for determining risks created by potential hazards represented by the industrial environment and transportation routes in the vicinity of a PWR, in order to verify design criteria acceptability with regard to such hazards

Potential environmental hazards of photovoltaic panel disposal: Discussion of Tammaro et al. (2015).

Science.gov (United States)

Sinha, Parikhit

2017-02-05

In their recent publication in Journal of Hazardous Materials (http://dx.doi.org/10.1016/j.jhazmat.2015.12.018), Tammaro et al. evaluate the potential environmental impacts of an illegal disposal scenario of photovoltaic panels in the European Union. Critical assumptions that underlie the study's conclusions would benefit from clarification. A scenario of photovoltaic panels finely crushed and abandoned in nature is not supported with field breakage data, in which photovoltaic panels remain largely intact with a number of glass fractures or cracks, as opposed to breakage into cm-scale pieces. Fate and transport analysis is necessary to evaluate how leachate transforms and disperses in moving from the point of emissions to the point of exposure, prior to making comparisons with drinking water limits. Some hazardous metal content has declined in both crystalline silicon and thin film panels, including a 50% decline in semiconductor material intensity in CdTe thin film panels (g CdTe/W) from 2009 to 2015. Waste laws, recycling requirements and minimum treatment standards under the EU WEEE Directive, and illegal disposal rates affect the accuracy of forecasts of releasable metal amounts from PV panels in Europe through 2050. Copyright © 2016 Elsevier B.V. All rights reserved.

A situational analysis of priority disaster hazards in Uganda: findings from a hazard and vulnerability analysis.

Science.gov (United States)

Mayega, R W; Wafula, M R; Musenero, M; Omale, A; Kiguli, J; Orach, G C; Kabagambe, G; Bazeyo, W

2013-06-01

Most countries in sub-Saharan Africa have not conducted a disaster risk analysis. Hazards and vulnerability analyses provide vital information that can be used for development of risk reduction and disaster response plans. The purpose of this study was to rank disaster hazards for Uganda, as a basis for identifying the priority hazards to guide disaster management planning. The study as conducted in Uganda, as part of a multi-country assessment. A hazard, vulnerability and capacity analysis was conducted in a focus group discussion of 7 experts representing key stakeholder agencies in disaster management in Uganda. A simple ranking method was used to rank the probability of occurance of 11 top hazards, their potential impact and the level vulnerability of people and infrastructure. In-terms of likelihood of occurance and potential impact, the top ranked disaster hazards in Uganda are: 1) Epidemics of infectious diseases, 2) Drought/famine, 3) Conflict and environmental degradation in that order. In terms of vulnerability, the top priority hazards to which people and infrastructure were vulnerable were: 1) Conflicts, 2) Epidemics, 3) Drought/famine and, 4) Environmental degradation in that order. Poverty, gender, lack of information, and lack of resilience measures were some of the factors promoting vulnerability to disasters. As Uganda develops a disaster risk reduction and response plan, it ought to prioritize epidemics of infectious diseases, drought/famine, conflics and environmental degradation as the priority disaster hazards.

EFSA Panels on Biological Hazards (BIOHAZ), on Contaminants in the Food Chain (CONTAM), and on Animal Health and Welfare (AHAW); Scientific Opinion on the public health hazards to be covered by inspection of meat (swine)

DEFF Research Database (Denmark)

Hald, Tine

2011-01-01

A qualitative risk assessment identified Salmonella spp., Yersinia enterocolitica, Toxoplasma gondii and Trichinella spp. as the most relevant biological hazards in the context of meat inspection of swine. A comprehensive pork carcass safety assurance is the only way to ensure their effective...... treatments if necessary. At farm level, risk reduction measures are based on herd health programmes, closed breeding pyramids and GHP/GFP. Chemical substances listed in Council Directive 96/23/EC were ranked into four categories. Dioxins, dioxin-like polychlorinated biphenyls and chloramphenicol were ranked...

Using consumption rate to assess potential predators for biological control of white perch

Directory of Open Access Journals (Sweden)

Gosch N.J.C.

2011-08-01

Full Text Available Control of undesirable fishes is important in aquatic systems, and using predation as a tool for biological control is an attractive option to fishery biologists. However, determining the appropriate predators for biological control is critical for success. The objective of this study was to evaluate the utility of consumption rate as an index to determine the most effective predators for biological control of an invasive fish. Consumption rate values were calculated for nine potential predators that prey on white perch Morone americana in Branched Oak and Pawnee reservoirs, Nebraska. The consumption rate index provided a unique and insightful means of determining the potential effectiveness of each predator species in controlling white perch. Cumulative frequency distributions facilitated interpretation by providing a graphical presentation of consumption rates by all individuals within each predator species. Largemouth bass Micropterus salmoides, walleye Sander vitreus and sauger S. canadensis were the most efficient white perch predators in both reservoirs; however, previous attempts to increase biomass of these predators have failed suggesting that successful biological control is unlikely using existing predator species in these Nebraska reservoirs.

Multi-Hazard Interactions in Guatemala

Science.gov (United States)

Gill, Joel; Malamud, Bruce D.

2017-04-01

In this paper, we combine physical and social science approaches to develop a multi-scale regional framework for natural hazard interactions in Guatemala. The identification and characterisation of natural hazard interactions is an important input for comprehensive multi-hazard approaches to disaster risk reduction at a regional level. We use five transdisciplinary evidence sources to organise and populate our framework: (i) internationally-accessible literature; (ii) civil protection bulletins; (iii) field observations; (iv) stakeholder interviews (hazard and civil protection professionals); and (v) stakeholder workshop results. These five evidence sources are synthesised to determine an appropriate natural hazard classification scheme for Guatemala (6 hazard groups, 19 hazard types, and 37 hazard sub-types). For a national spatial extent (Guatemala), we construct and populate a "21×21" hazard interaction matrix, identifying 49 possible interactions between 21 hazard types. For a sub-national spatial extent (Southern Highlands, Guatemala), we construct and populate a "33×33" hazard interaction matrix, identifying 112 possible interactions between 33 hazard sub-types. Evidence sources are also used to constrain anthropogenic processes that could trigger natural hazards in Guatemala, and characterise possible networks of natural hazard interactions (cascades). The outcomes of this approach are among the most comprehensive interaction frameworks for national and sub-national spatial scales in the published literature. These can be used to support disaster risk reduction and civil protection professionals in better understanding natural hazards and potential disasters at a regional scale.

SRL process hazards review manual

International Nuclear Information System (INIS)

1980-08-01

The principal objective of the Process Hazards Management Program is to provide a regular, systematic review of each process at the Savannah River Laboratory (SRL) to eliminate injuries and to minimize property damage resulting from process hazards of catastrophic potential. Management effort is directed, through the Du Pont Safety Program, toward those controls and practices that ensure this objective. The Process Hazards Management Program provides an additional dimension to further ensure the health and safety of employees and the public. Du Pont has concluded that an organized approach is essential to obtain an effective and efficient process hazards review. The intent of this manual is to provide guidance in creating such an organized approach to performing process hazards reviews on a continuing basis

Energy and solid/hazardous waste

Energy Technology Data Exchange (ETDEWEB)

None

1981-12-01

This report addresses the past and potential future solid and hazardous waste impacts from energy development, and summarizes the major environmental, legislation applicable to solid and hazardous waste generation and disposal. A glossary of terms and acronyms used to describe and measure solid waste impacts of energy development is included. (PSB)

Energy and solid/hazardous waste

International Nuclear Information System (INIS)

1981-12-01

This report addresses the past and potential future solid and hazardous waste impacts from energy development, and summarizes the major environmental, legislation applicable to solid and hazardous waste generation and disposal. A glossary of terms and acronyms used to describe and measure solid waste impacts of energy development is included

Occupational Health Hazards among Healthcare Workers in Kampala, Uganda

Directory of Open Access Journals (Sweden)

Rawlance Ndejjo

2015-01-01

Full Text Available Objective. To assess the occupational health hazards faced by healthcare workers and the mitigation measures. Methods. We conducted a cross-sectional study utilizing quantitative data collection methods among 200 respondents who worked in 8 major health facilities in Kampala. Results. Overall, 50.0% of respondents reported experiencing an occupational health hazard. Among these, 39.5% experienced biological hazards while 31.5% experienced nonbiological hazards. Predictors for experiencing hazards included not wearing the necessary personal protective equipment (PPE, working overtime, job related pressures, and working in multiple health facilities. Control measures to mitigate hazards were availing separate areas and containers to store medical waste and provision of safety tools and equipment. Conclusion. Healthcare workers in this setting experience several hazards in their workplaces. Associated factors include not wearing all necessary protective equipment, working overtime, experiencing work related pressures, and working in multiple facilities. Interventions should be instituted to mitigate the hazards. Specifically PPE supply gaps, job related pressures, and complacence in adhering to mitigation measures should be addressed.

Evaluating and Addressing Potential Hazards of Fuel Tanks Surviving Atmospheric Reentry

Science.gov (United States)

Kelley, Robert L.; Johnson, Nicholas L.

2011-01-01

In order to ensure reentering spacecraft do not pose an undue risk to the Earth's population it is important to design satellites and rocket bodies with end of life considerations in mind. In addition to considering the possible consequences of deorbiting a vehicle, consideration must also be given to the possible risks associated with a vehicle failing to become operational or reach its intended orbit. Based on recovered space debris and numerous reentry survivability analyses, fuel tanks are of particular concern in both of these considerations. Most spacecraft utilize some type of fuel tank as part of their propulsion system. These fuel tanks are most often constructed using stainless steel or titanium and are filled with potentially hazardous substances such as hydrazine and nitrogen tetroxide. For a vehicle which has reached its scheduled end of mission the contents of the tanks are typically depleted. In this scenario the use of stainless steel and titanium results in the tanks posing a risk to people and property do to the high melting point and large heat of ablation of these materials leading to likely survival of the tank during reentry. If a large portion of the fuel is not depleted prior to reentry, there is the added risk of hazardous substance being released when the tank impact the ground. This paper presents a discussion of proactive methods which have been utilized by NASA satellite projects to address the risks associated with fuel tanks reentering the atmosphere. In particular it will address the design of a demiseable fuel tank as well as the evaluation of off the shelf designs which are selected to burst during reentry.

3D-printed biological organs: medical potential and patenting opportunity.

Science.gov (United States)

Yoo, Seung-Schik

2015-05-01

Three-dimensional (3D) bioprinting has emerged as a new disruptive technology that may address the ever-increasing demand for organ transplants. 3D bioprinting offers many technical features that allow for building functional biological tissue constructs by dispensing the individual or group of cells into specific locations along with various types of bio-scaffold materials and extracellular matrices, and thus, may provide flexibility needed for on-demand individualized construction of biological organs. Several key classes of 3D bioprinting techniques are reviewed, including potential medical and industrial applications. Several unanswered engineering components for the ultimate creation of printed biological organs are also discussed. The complicated nature of the human organs, in addition to the legal and ethical requirements for safe implantation into the human body, would require significant research and development to produce marketable bioprinted organs. This also suggests the possibility for further patenting and licensing opportunities from different sectors of the economy.

Hydrothermal Liquefaction Treatment Preliminary Hazard Analysis Report

Energy Technology Data Exchange (ETDEWEB)

Lowry, Peter P.; Wagner, Katie A.

2015-08-31

A preliminary hazard assessment was completed during February 2015 to evaluate the conceptual design of the modular hydrothermal liquefaction treatment system. The hazard assessment was performed in 2 stages. An initial assessment utilizing Hazard Identification and Preliminary Hazards Analysis (PHA) techniques identified areas with significant or unique hazards (process safety-related hazards) that fall outside of the normal operating envelope of PNNL and warranted additional analysis. The subsequent assessment was based on a qualitative What-If analysis. This analysis was augmented, as necessary, by additional quantitative analysis for scenarios involving a release of hazardous material or energy with the potential for affecting the public.

The use of hazards analysis in the development of training

Energy Technology Data Exchange (ETDEWEB)

Houghton, F.K.

1998-03-01

When training for a job in which human error has the potential of producing catastrophic results, an understanding of the hazards that may be encountered is of paramount importance. In high consequence activities, it is important that the training program be conducted in a safe environment and yet emphasize the potential hazards. Because of the high consequence of a human error the use of a high-fidelity simulation is of great importance to provide the safe environment the worker needs to learn and hone required skills. A hazards analysis identifies the operation hazards, potential human error, and associated positive measures that aid in the mitigation or prevention of the hazard. The information gained from the hazards analysis should be used in the development of training. This paper will discuss the integration of information from the hazards analysis into the development of simulation components of a training program.

The Impact Hazard in the Context of Other Natural Hazards and Predictive Science

Science.gov (United States)

Chapman, C. R.

1998-09-01

The hazard due to impact of asteroids and comets has been recognized as analogous, in some ways, to other infrequent but consequential natural hazards (e.g. floods and earthquakes). Yet, until recently, astronomers and space agencies have felt no need to do what their colleagues and analogous agencies must do in order the assess, quantify, and communicate predictions to those with a practical interest in the predictions (e.g. public officials who must assess the threats, prepare for mitigation, etc.). Recent heightened public interest in the impact hazard, combined with increasing numbers of "near misses" (certain to increase as Spaceguard is implemented) requires that astronomers accept the responsibility to place their predictions and assessments in terms that may be appropriately considered. I will report on preliminary results of a multi-year GSA/NCAR study of "Prediction in the Earth Sciences: Use and Misuse in Policy Making" in which I have represented the impact hazard, while others have treated earthquakes, floods, weather, global climate change, nuclear waste disposal, acid rain, etc. The impact hazard presents an end-member example of a natural hazard, helping those dealing with more prosaic issues to learn from an extreme. On the other hand, I bring to the astronomical community some lessons long adopted in other cases: the need to understand the policy purposes of impact predictions, the need to assess potential societal impacts, the requirements to very carefully assess prediction uncertainties, considerations of potential public uses of the predictions, awareness of ethical considerations (e.g. conflicts of interest) that affect predictions and acceptance of predictions, awareness of appropriate means for publicly communicating predictions, and considerations of the international context (especially for a hazard that knows no national boundaries).

Management, treatment and final disposal of solid hazardous hospital wastes

International Nuclear Information System (INIS)

Sebiani Serrano, T.

2000-01-01

Medical Waste is characterized by its high risk to human health and the environment. The main risk is biological, due to the large amount of biologically contaminated materials present in such waste. However, this does not mean that the chemical and radioactive wastes are less harmful just because they represent a smaller part of the total waste. Hazardous wastes from hospitals can be divided in 3 main categories: Solid Hazardous Hospital Wastes (S.H.H.W.), Liquid Hazardous Hospital Wastes (L.H.H.W.) and Gaseous Hazardous Hospital Wastes (G.H.H.W.) Most gaseous and liquid hazardous wastes are discharged to the environment without treatment. Since this inappropriate disposal practice, however, is not visible to society, there is no societal reaction to such problem. On the contrary, hazardous solid wastes (S.H.H.W.) are visible to society and create worries in the population. As a result, social and political pressures arise, asking for solutions to the disposal problems of such wastes. In response to such pressures and legislation approved by Costa Rica on waste handling and disposal, the Caja Costarricense de Seguro Social developed a plan for the handling, treatment, and disposal of hazardous solid wastes at the hospitals and clinics of its system. The objective of the program is to reduce the risk to society of such wastes. In this thesis a cost-effectiveness analysis was conducted to determine the minimum cost at which it is possible to reach a maximum level of reduction in hazardous wastes, transferring to the environment the least possible volume of solid hazardous wastes, and therefore, reducing risk to a minimum. It was found that at the National Children's Hospital the internal handling of hazard solid wastes is conducted with a high level of effectiveness. However, once out of the hospital area, the handling is not effective, because hazardous and common wastes are all mixed together creating a larger amount of S.H.H.W. and reducing the final efficiency

The implementation of a Hazard Analysis and Critical Control Point management system in a peanut butter ice cream plant

Directory of Open Access Journals (Sweden)

Yu-Ting Hung

2015-09-01

Full Text Available To ensure the safety of the peanut butter ice cream manufacture, a Hazard Analysis and Critical Control Point (HACCP plan has been designed and applied to the production process. Potential biological, chemical, and physical hazards in each manufacturing procedure were identified. Critical control points for the peanut butter ice cream were then determined as the pasteurization and freezing process. The establishment of a monitoring system, corrective actions, verification procedures, and documentation and record keeping were followed to complete the HACCP program. The results of this study indicate that implementing the HACCP system in food industries can effectively enhance food safety and quality while improving the production management.

Thinning and prescribed fire and projected trends in wood product potential, financial return, and fire hazard in Montana.

Science.gov (United States)

R. James Barbour; Roger D. Fight; Glenn A. Christensen; Guy L. Pinjuv; Rao V. Nagubadi

2004-01-01

This work was undertaken under a joint fire science project "Assessing the need, costs, and potential benefits of prescribed fire and mechanical treatments to reduce fire hazard." This paper compares the future mix of timber products under two treatment scenarios for the state of Montana. We developed and demonstrated an analytical method that uses readily...

Hazards Analysis for the Spent Nuclear Fuel L-Experimental Facility

International Nuclear Information System (INIS)

Blanchard, A.

1999-01-01

The purpose of this Hazard Analysis (HA) is to identify and assess potential hazards associated with the operations of the Spent Nuclear Fuels (SNF) Treatment and Storage Facility LEF. Additionally, this HA will be used for identifying and assessing potential hazards and specifying functional attributes of SSCs for the LEF project

Biological fate, transport, and ecotoxicity of toxic and hazardous waste in the Mississippi River Basin

International Nuclear Information System (INIS)

Abdelghani, A.; Hartley, W.; Bart, H.; Ide, C.; Ellgaard, E.; Sherry, T.; Devall, M.; Thien, L.; Horner, E.; Mizell, M.

1993-01-01

The objective of the cluster investigators is to develop a dynamic model for the evaluation of the biological fate, transport, and ecotoxicity from multiple chemical contamination of the Mississippi River Basin. To develop this environmental model, FY 93-94 most of cluster investigators focused on Devil's Swamp Site (DSS), a cypress swamp which lies just Northwest of Baton Rouge, Louisiana, adjacent to the Mississippi River. The DSS which includes a man-made lake has contaminated sediment, water and biota. The DSS receives flood water from the Mississippi River during high flow periods and the Baton Rouge Bayou drains through the DSS. The DSS receives toxic substances and hazardous waste from a wide variety of surrounding industrial operations including an abandoned hazardous waste disposal facility. In addition, some investigators studied Bayou Trepangnier. This research cluster will continue studying Devil Swamp. The large number of investigators in this cluster resulted from incorporating related research proposals based on reviewer recommendations. The specific aims of the cluster for the first year were to conduct a physical, chemical, ecological survey and baseline toxicological characterization of the DSS from existing databases maintained by State and federal agencies, field studies (assessment) of sediment, air, water and biota, and laboratory screening studios. This assessment will provide critical information and focus for the next two years in-depth studies of critical transport and fate processes, ecotoxicity, biomarkers of effect, and uptake, metabolism and distribution of toxicants. The primary significant outcome of the cluster researchers will be the development of an ecological risk assessment model combining biotic and physical/chemical variables for DSS with a projection of model reliability and accuracy for use at other typical Mississippi River Basin sites

The use of total detriment in radiation protection and its potential extension to other hazards

International Nuclear Information System (INIS)

Johnson, J.R.; Stansbury, P.S.; Selby, J.M.

1991-10-01

Before publication of the 1977 recommendations of the International Commission on Radiological Protection (ICRP), radiation protection standards were based on dose limits to single organs. These dose limits were only loosely linked to the expected effects in the first two generations from gonadal doses and to the risk of fatal cancer from doses to specific organs. In 1977, the ICRP recommended the use of the ''effective dose equivalent (EDE),'' which is a method of summing the doses (weighted with relative risk coefficients) to all organs and tissues, and recommended an annual limit for EDE. Since the 1977 recommendations were published, a ''total risk'' or total detriment approach has been extended to include nonfatal cancers and genetic effects for all subsequent generations, i.e., the total health detriment from low doses of ionizing radiation. This paper discusses the development of this total health detriment from ionizing radiation exposures, and explores potential methods for using it with other hazards (such as exposures to other physical agents, hazardous chemicals, and fatal and nonfatal accidents) in calculating the total detriment to a worker

Prioritization of pharmaceuticals for potential environmental hazard through leveraging a large scale mammalian pharmacological dataset

Science.gov (United States)

To proceed in the investigation of potential effects of thousands of active pharmaceutical ingredients (API) which may enter the aquatic environment, a cohesive research strategy, specifically a prioritization is paramount. API are biologically active, with specific physiologica...

Reactions of copper macrocycles with antioxidants and HOCl: potential for biological redox sensing.

Science.gov (United States)

Sowden, Rebecca J; Trotter, Katherine D; Dunbar, Lynsey; Craig, Gemma; Erdemli, Omer; Spickett, Corinne M; Reglinski, John

2013-02-01

A series of simple copper N(2)S(2) macrocycles were examined for their potential as biological redox sensors, following previous characterization of their redox potentials and crystal structures. The divalent species were reduced by glutathione or ascorbate at a biologically relevant pH in aqueous buffer. A less efficient reduction was also achieved by vitamin E in DMSO. Oxidation of the corresponding univalent copper species by sodium hypochlorite resulted in only partial (~65 %) recovery of the divalent form. This was concluded to be due to competition between metal oxidation and ligand oxidation, which is believed to contribute to macrocycle demetallation. Electrospray mass spectrometry confirmed that ligand oxidation had occurred. Moreover, the macrocyclic complexes could be demetallated by incubation with EDTA and bovine serum albumin, demonstrating that they would be inappropriate for use in biological systems. The susceptibility to oxidation and demetallation was hypothesized to be due to oxidation of the secondary amines. Consequently these were modified to incorporate additional oxygen donor atoms. This modification led to greater resistance to demetallation and ligand oxidation, providing a better platform for further development of copper macrocycles as redox sensors for use in biological systems.

Biological agents with potential for misuse: a historical perspective and defensive measures

International Nuclear Information System (INIS)

Bhalla, Deepak K.; Warheit, David B.

2004-01-01

Biological and chemical agents capable of producing serious illness or mortality have been used in biowarfare from ancient times. Use of these agents has progressed from crude forms in early and middle ages, when snakes and infected cadavers were used as weapons in battles, to sophisticated preparations for use during and after the second World War. Cults and terrorist organizations have attempted the use of biological agents with an aim to immobilize populations or cause serious harm. The reasons for interest in these agents by individuals and organizations include relative ease of acquisition, potential for causing mass casualty or panic, modest financing requirement, availability of technology, and relative ease of delivery. The Centers for Disease Control and Prevention has classified Critical Biological Agents into three major categories. This classification was based on several criteria, which include severity of impact on human health, potential for delivery in a weapon, capacity to cause panic and special needs for development, and stockpiling of medication. Agents that could cause the greatest harm following deliberate use were placed in category A. Category B included agents capable of producing serious harm and significant mortality but of lower magnitude than category A agents. Category C included emerging pathogens that could be developed for mass dispersion in future and their potential as a major health threat. A brief description of the category A bioagents is included and the pathophysiology of two particularly prominent agents, namely anthrax and smallpox, is discussed in detail. The potential danger from biological agents and their ever increasing threat to human populations have created a need for developing technologies for their early detection, for developing treatment strategies, and for refinement of procedures to ensure survival of affected individuals so as to attain the ultimate goal of eliminating the threat from intentional use of

Biological agents with potential for misuse: a historical perspective and defensive measures.

Science.gov (United States)

Bhalla, Deepak K; Warheit, David B

2004-08-15

Biological and chemical agents capable of producing serious illness or mortality have been used in biowarfare from ancient times. Use of these agents has progressed from crude forms in early and middle ages, when snakes and infected cadavers were used as weapons in battles, to sophisticated preparations for use during and after the second World War. Cults and terrorist organizations have attempted the use of biological agents with an aim to immobilize populations or cause serious harm. The reasons for interest in these agents by individuals and organizations include relative ease of acquisition, potential for causing mass casualty or panic, modest financing requirement, availability of technology, and relative ease of delivery. The Centers for Disease Control and Prevention has classified Critical Biological Agents into three major categories. This classification was based on several criteria, which include severity of impact on human health, potential for delivery in a weapon, capacity to cause panic and special needs for development, and stockpiling of medication. Agents that could cause the greatest harm following deliberate use were placed in category A. Category B included agents capable of producing serious harm and significant mortality but of lower magnitude than category A agents. Category C included emerging pathogens that could be developed for mass dispersion in future and their potential as a major health threat. A brief description of the category A bioagents is included and the pathophysiology of two particularly prominent agents, namely anthrax and smallpox, is discussed in detail. The potential danger from biological agents and their ever increasing threat to human populations have created a need for developing technologies for their early detection, for developing treatment strategies, and for refinement of procedures to ensure survival of affected individuals so as to attain the ultimate goal of eliminating the threat from intentional use of

Toxic hazards of underground excavation

International Nuclear Information System (INIS)

Smith, R.; Chitnis, V.; Damasian, M.

1982-09-01

Inadvertent intrusion into natural or man-made toxic or hazardous material deposits as a consequence of activities such as mining, excavation or tunnelling has resulted in numerous deaths and injuries in this country. This study is a preliminary investigation to identify and document instances of such fatal or injurious intrusion. An objective is to provide useful insights and information related to potential hazards due to future intrusion into underground radioactive-waste-disposal facilities. The methodology used in this study includes literature review and correspondence with appropriate government agencies and organizations. Key categories of intrusion hazards are asphyxiation, methane, hydrogen sulfide, silica and asbestos, naturally occurring radionuclides, and various mine or waste dump related hazards

Toxic hazards of underground excavation

Energy Technology Data Exchange (ETDEWEB)

Smith, R.; Chitnis, V.; Damasian, M.; Lemm, M.; Popplesdorf, N.; Ryan, T.; Saban, C.; Cohen, J.; Smith, C.; Ciminesi, F.

1982-09-01

Inadvertent intrusion into natural or man-made toxic or hazardous material deposits as a consequence of activities such as mining, excavation or tunnelling has resulted in numerous deaths and injuries in this country. This study is a preliminary investigation to identify and document instances of such fatal or injurious intrusion. An objective is to provide useful insights and information related to potential hazards due to future intrusion into underground radioactive-waste-disposal facilities. The methodology used in this study includes literature review and correspondence with appropriate government agencies and organizations. Key categories of intrusion hazards are asphyxiation, methane, hydrogen sulfide, silica and asbestos, naturally occurring radionuclides, and various mine or waste dump related hazards.

Radon hazard map in Bas-Rhin, final report

International Nuclear Information System (INIS)

2010-01-01

After a presentation of radon (geochemical properties, origin, emanation and transfer to surface, related health hazard, exposure factor, modalities for the struggle against radon), of the study context, framework and objective, and of the Bas-Rhin geological context, this report presents the exploited data: definition of the geological uranium potential, direct measurements and geochemical analysis, indicators (lithologic characterization, surface radioactivity, drifting alluvial deposits), factors promoting inhalation, measurements in buildings. It presents and comments maps of the radon geological potential and of radon hazard. It proposes an assessment of radon potential hazard for different areas of the district, and reports measurements performed in Strasbourg, Eckbolsheim, Bischeim and Haguenau

Toxicology primer: understanding workplace hazards and protecting worker health.

Science.gov (United States)

Arble, Janice

2004-06-01

Hazardous substances are ubiquitous in the environment and common in industrialized societies. Serious harm can occur with sufficient exposures under certain conditions. However, much harm can be avoided if hazardous substances are handled with respect and appreciation for their use and potential. Occupational health nurses must be aware of potential hazards to employees in the work environment and apply scientific principles to their practice of promoting worker safety and health.

Hazardous materials in aquatic environments of the Mississippi River Basin. Quarterly project status report, July 1, 1994--September 30, 1994

International Nuclear Information System (INIS)

1994-01-01

This document references information pertaining to the presence of hazardous materials in the Mississippi River Basin. Topics discussed include: The biological fate, transport, and ecotoxicity of toxic and hazardous wastes; biological uptake and metabolism; sentinels of aquatic contamination; bioremediation; microorganisms; biomarkers of exposure and ecotoxicity; expert geographical information systems for assessing hazardous wastes in aquatic environments; and enhancement of environmental education at Tulane and Xavier

The potential impact of proposed hazardous air pollutant legislation on the US refining industry

International Nuclear Information System (INIS)

1989-11-01

The Administration has recently submitted a Clean Air Act Bill to Congress which would significantly modify the regulatory treatment of industrial hazardous air pollutants (air toxics). The adverse economic impacts of this legislation on the petroleum refining industry could be substantial. Depending on how EPA interprets the legislative language, the capital costs of compliance for the proposed bill could range from $1.3 to $15.0 billion. At the upper end of the range, costs of this order of magnitude would be over 2.5 times larger than the combined estimated cost of EPAs gasoline volatility (RVP) regulations and the proposed diesel sulfur content regulations. Potential compliance costs could be as much as $0.40 per barrel processed for large, complex refineries and as much as $0.50 per barrel for some small, simple refineries. For perspective, total refining costs, including a normal return on investment, are $4--5 per barrel. Because foreign refineries supplying the US will not be affected by the US air toxics regulations, US refineries may not be able to raise prices sufficiently to recover their compliance costs. For this reason, the air toxic legislation may put US refineries at an economic disadvantage relative to foreign competitors. Even under the best petroleum product market conditions, costs of $0.40 to $0.50 per barrel processed could reduce US Gulf refiner cash operating margins by as much as 29 percent. Under less favorable market conditions, such as the mid-80's when refiners were losing money, the hazardous air pollutant regulations could greatly increase US refiner operating losses and potentially lead to closure of some marginal refineries

30 CFR 47.53 - Alternative for hazardous waste.

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Alternative for hazardous waste. 47.53 Section... waste. If the mine produces or uses hazardous waste, the operator must provide potentially exposed miners and designated representatives access to available information for the hazardous waste that— (a...

High organic containing tanks: Assessing the hazard potential

International Nuclear Information System (INIS)

Hill, R.C.P.; Babad, H.

1991-09-01

Eight Hanford Site tanks contain organic chemicals at concentrations believed to be greater than 10 mole percent sodium acetate equivalent mixed with the oxidizing salts sodium nitrate/sodium nitrite. Also, three of the hydrogen and ferrocyanide tanks appear on the organic tank list. Concentrations of organics that may be present in some tanks could cause an exothermic reaction given a sufficient driving force, such as high temperatures. However, the difference between ignition temperatures and actual tank temperatures measured is so large that the probability of such a reaction is considered very low. The consequences of the postulated reaction are about the same as the scenarios for an explosion in a ''burping'' hydrogen tank. Although work on this issue is just beginning, consideration of hazards associated with heating nitrate-nitrite mixtures containing organic materials is an integral part of both the hydrogen and ferrocyanide tank efforts. High concentrations of organic compounds have been inferred (from tank transfer, flow sheet records, and limited analytical data) in eight single-shell tanks. Many organic chemicals, if present in concentrations above 10 dry weight percent (sodium acetate equivalent), have the potential to react with nitrate-nitrites constituents at temperatures above 200 degree C (392 degree F) in an exothermic manner. The concentrations of organic materials in the listed single-shell tanks, and their chemical identity, is not accurately known at present. A tank sampling program has been planned to provide more information on the contents of these tanks and to serve as a basis for laboratory testing and safety evaluations. 2 refs., 1 fig., 2 tabs

Biological effects data: Fluoride and sulfur dioxide

Energy Technology Data Exchange (ETDEWEB)

McMechan, K.J. (ed.); Holton, R.L.; Ulbricht, R.J.; Morgan , J.B.

1975-04-01

The Alumax Pacific Aluminum Corporation has proposed construction of an aluminum reduction facility near Youngs Bay at Warrenton, Oregon. This report comprises one part of the final report to Alumax on a research project entitled, Physical, Chemical and Biological Studies of Youngs Bay.'' It presents data pertaining to the potential biological effects of fluoride and sulfur dioxide, two potentially hazardous plant-stack emissions, on selected aquatic species of the area. Companion volumes provide a description of the physical characteristics the geochemistry, and the aquatic animals present in Youngs Bay and adjacent ecosystems. An introductory volume provides general information and maps of the area, and summarizes the conclusions of all four studies. The data from the two phases of the experimental program are included in this report: lethal studies on the effects of selected levels of fluoride and sulfur dioxide on the survival rate of eleven Youngs Bay faunal species from four phyla, and sublethal studies on the effects of fluoride and sulfur dioxide on the rate of primary production of phytoplankton. 44 refs., 18 figs., 38 tabs.

222 S Laboratory complex hazards assessment

International Nuclear Information System (INIS)

Sutton, L.N.

1998-01-01

This report documents the hazards assessment for the 222-S Analytical Laboratory located on the US Department of Energy (DOE) Hanford Site. Operation of the laboratory is the responsibility of Waste Management Federal Services, Inc. (WMFS). This hazards assessment was conducted to provide the emergency planning technical basis for the 222-S Facility. DOE Orders require an emergency planning hazards assessment for each facility that has the potential to reach or exceed the lowest level emergency classification

Occupational injuries and illnesses in rubber factory: Profile, Potential Hazards and possible prevention

Directory of Open Access Journals (Sweden)

Tri Hari Irfani

2015-12-01

Full Text Available Rubber is one of the important commodities in the world. Globally, workers are facing so many problems of hazards that produce by rubber process. In Indonesia, there are several data of occupational problems such as respiratory diseases, muscle and skeletal diseases, gastrointestinal diseases, diseases of the teeth and oral cavity, skin diseases and skin tissue. In Iranian rubber factory, Iran, workers had suffered from some kind of musculoskeletal symptoms. Stomach and liver cancers in workers are having in Shanghai tire factory. In addition, Germany has cancer problem of their workers who work in rubber factory. Most of the rubber process in the factory can cause some hazards of the workers. In unloading area and area that operator is taking the dirt manually, workers are facing ergonomic problems. The possible control is reduce weight of load, team lift the object with two or more workers and Use mechanical assist. Machine safeguarding is essential for protecting from Cutting process that can make workers amputation organs such as hands, and fingers. In bale process, the workers need to cut raw rubber into bale in bale cutting. Furthermore, workers are facing with amputation problem. To manage that, It must be designed as a standard which has interlocking guards to prevent access to the cutting area. When wrapped using plastic, workers use a heated iron and sticked in plastic so that it blends neatly. The risks are fingers can cut accidently and then the workers also get contamination from polyvinyl chloride (PVC. The possible preventions are use an automatic plastic wrapping machine with palletized product sitting on a turntable and respirator. Another problem is contact dermatitis that has been reported frequently among rubber workers. The prevention for that problem is using Gloves. The aim of researcher is to provide the profile of occupational injuries and illnesses, potential hazards in rubber factory to prevent the workers.

CHIP: Commodity based Hazard Identification Protocol for emerging diseases in plants and animals

NARCIS (Netherlands)

Bremmer, J.; Swanenburg, M.; Galen, van M.A.; Hoek, Maarten; Rau, M.L.; Hennen, W.H.G.J.; Benninga, J.; Ge, L.; Breukers, M.L.H.

2012-01-01

This project comprised the development of a commodity-based hazard identification protocol for biological hazards in plants and animals as a decision support tree programmed in Excel. The content of the decision tree is based on the results of a systematic review of pest and pathogen

The California Hazards Institute

Science.gov (United States)

Rundle, J. B.; Kellogg, L. H.; Turcotte, D. L.

2006-12-01

California's abundant resources are linked with its natural hazards. Earthquakes, landslides, wildfires, floods, tsunamis, volcanic eruptions, severe storms, fires, and droughts afflict the state regularly. These events have the potential to become great disasters, like the San Francisco earthquake and fire of 1906, that overwhelm the capacity of society to respond. At such times, the fabric of civic life is frayed, political leadership is tested, economic losses can dwarf available resources, and full recovery can take decades. A patchwork of Federal, state and local programs are in place to address individual hazards, but California lacks effective coordination to forecast, prevent, prepare for, mitigate, respond to, and recover from, the harmful effects of natural disasters. Moreover, we do not know enough about the frequency, size, time, or locations where they may strike, nor about how the natural environment and man-made structures would respond. As California's population grows and becomes more interdependent, even moderate events have the potential to trigger catastrophes. Natural hazards need not become natural disasters if they are addressed proactively and effectively, rather than reactively. The University of California, with 10 campuses distributed across the state, has world-class faculty and students engaged in research and education in all fields of direct relevance to hazards. For that reason, the UC can become a world leader in anticipating and managing natural hazards in order to prevent loss of life and property and degradation of environmental quality. The University of California, Office of the President, has therefore established a new system-wide Multicampus Research Project, the California Hazards Institute (CHI), as a mechanism to research innovative, effective solutions for California. The CHI will build on the rich intellectual capital and expertise of the Golden State to provide the best available science, knowledge and tools for

Potential health hazards of radiation. Fact Sheet

International Nuclear Information System (INIS)

2009-01-01

During World War II and the Cold War, the federal government developed and operated industrial facilities for the research, production, and testing of nuclear weapons, as well as other scientific and engineering research. These processes left a legacy of radioactive and chemical waste, environmental contamination, and hazardous facilities and materials at well over 100 sites. Some of these sites processed uranium and vanadium, and upon closure, left behind millions of cubic yards of mill tailings on the sites and throughout the nearby communities. The U.S. Department of Energy (DOE) administers the cleanup of these areas to minimize the risks to the public and environment from exposure to the tailings and the radon gas they produce

Water reuse potential in truck wash using a Rotating Biological Contactor

OpenAIRE

Eduardo Lucas Subtil; José Carlos Mierzwa; Ivanildo Hespanhol; Raphael Rodrigues

2016-01-01

This study evaluated the water reuse potential for truck washing using the effluent treated by a Rotating Biological Contactor (RBC) operated in full scale. In order to evaluate the reuse potential, a mass balance was performed for the reuse system taking into account the concentration of Total Dissolved Solids as the critical contaminant. The treatment system produced an effluent with average concentration of color, turbidity, TDS and BOD5 of 45 ± 14 uC, 15 ± 6.0 NTU, 244 ± 99 mg TDS / L and...

Biological effects and hazards of radiation exposure

International Nuclear Information System (INIS)

Boas, J.F.; Solomon, S.B.

1990-01-01

Radiation induced carcinogenesis and mutagenesis form the main risk to health from exposure to low levels of radiation. This risk effects can be at least qualitatively understood by considering the effects of radiation on cell DNA. Whilst exposure to high levels of radiation results in a number of identifiable effects, exposure to low levels of radiation may result in effects which only manifest themselves after many years. Risk estimates for low levels of radiation have been derived on the basis of a number of assumptions. In the case of uranium mine workers a major hazard arises from the inhalation of radon daughters. Whilst the correlation between radon daughter exposure and lung cancer incidence is well established, the numerical value of the risk factor is the subject of controversy. ICRP 50 gives a value of 10 cases per 10 6 person-years at risk per WLM (range 5-15 x 10 -6 PYR -1 WLM -1 ). The effect of smoking on lung cancer incidence rates amongst miners is also controversial. Nevertheless, smoking by miners should be discouraged

Hazard Communication Standard

International Nuclear Information System (INIS)

Sichak, S.

1991-01-01

The current rate of technological advances has brought with it an overwhelming increase in the usage of chemicals in the workplace and in the home. Coupled to this increase has been a heightened awareness in the potential for acute and chronic injuries attributable to chemical insults. The Hazard Communication Standard has been introduced with the desired goal of reducing workplace exposures to hazardous substances and thereby achieving a corresponding reduction in adverse health effects. It was created and proclaimed by the US Department of Labor and regulated by the Occupational Safety and Health Administration. 1 tab

Analysis of abandoned potential CERCLA hazardous waste sites using historic aerial photographs

International Nuclear Information System (INIS)

Rosowitz, D.W.; Franzen, P.A.; Green, D.J.

1993-01-01

Aerial photographs of varying scale from federal agencies and commercial aerial service companies covering the years 1938, 1942, 1948, 1952, 1957, 1960, 1970, 1971, 1977, and 1986 of the Edgewood Area of Aberdeen Proving Ground (APG), Maryland, (Gunpowder Neck 7.5 Minute United States Geological Survey Topographic Quadrangle Map) were evaluated for identification of potential Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) hazardous waste sites and land use changes for approximately 1500 acres (610 hectares) used in the testing of military-related chemicals and munitions on Carroll Island and Graces Quarters. Detailed testing records exist only for July 1964 to December 1971, thus making the interpretation of aerial photographs a valuable tool in reconstructing past activities from the late 1930s to June 1964 and guiding future sampling locations in the multiphased CERCLA process. Many potential test sites were activated by either clear-cutting tracks of vegetation or using existing cleared land until final abandonment of the site(s) circa 1974-1975. Ground inspection of open-quotes land scarringclose quotes at either known or suspected sites was essential for verifying the existence, location, and subsequent sampling of potential CERCLA sites. Photomorphic mapping techniques are described to delineate and compare different land use changes in past chemical and munitions handling and testing. Delineation of features was based on photographic characteristics of tone, pattern, texture, shape, shadow, size, and proximity to known features. 7 refs., 9 figs

Visual event-related potentials to biological motion stimuli in autism spectrum disorders

Science.gov (United States)

Bletsch, Anke; Krick, Christoph; Siniatchkin, Michael; Jarczok, Tomasz A.; Freitag, Christine M.; Bender, Stephan

2014-01-01

Atypical visual processing of biological motion contributes to social impairments in autism spectrum disorders (ASD). However, the exact temporal sequence of deficits of cortical biological motion processing in ASD has not been studied to date. We used 64-channel electroencephalography to study event-related potentials associated with human motion perception in 17 children and adolescents with ASD and 21 typical controls. A spatio-temporal source analysis was performed to assess the brain structures involved in these processes. We expected altered activity already during early stimulus processing and reduced activity during subsequent biological motion specific processes in ASD. In response to both, random and biological motion, the P100 amplitude was decreased suggesting unspecific deficits in visual processing, and the occipito-temporal N200 showed atypical lateralization in ASD suggesting altered hemispheric specialization. A slow positive deflection after 400 ms, reflecting top-down processes, and human motion-specific dipole activation differed slightly between groups, with reduced and more diffuse activation in the ASD-group. The latter could be an indicator of a disrupted neuronal network for biological motion processing in ADS. Furthermore, early visual processing (P100) seems to be correlated to biological motion-specific activation. This emphasizes the relevance of early sensory processing for higher order processing deficits in ASD. PMID:23887808

The implementation of a Hazard Analysis and Critical Control Point management system in a peanut butter ice cream plant.

Science.gov (United States)

Hung, Yu-Ting; Liu, Chi-Te; Peng, I-Chen; Hsu, Chin; Yu, Roch-Chui; Cheng, Kuan-Chen

2015-09-01

To ensure the safety of the peanut butter ice cream manufacture, a Hazard Analysis and Critical Control Point (HACCP) plan has been designed and applied to the production process. Potential biological, chemical, and physical hazards in each manufacturing procedure were identified. Critical control points for the peanut butter ice cream were then determined as the pasteurization and freezing process. The establishment of a monitoring system, corrective actions, verification procedures, and documentation and record keeping were followed to complete the HACCP program. The results of this study indicate that implementing the HACCP system in food industries can effectively enhance food safety and quality while improving the production management. Copyright © 2015. Published by Elsevier B.V.

Thinning and prescribed fire and projected trends in wood product potential, financial return, and fire hazard in New Mexico.

Science.gov (United States)

Roger D. Fight; R. James Barbour; Glenn Christensen; Guy L. Pinjuv; Rao V. Nagubadi

2004-01-01

This work was undertaken under a joint fire science project "Assessing the need, costs, and potential benefits of prescribed fire and mechanical treatments to reduce fire hazard." This paper compares the future mix of timber projects under two treatment scenarios for New Mexico.We developed and demonstrated an analytical method that uses readily available...

Chemical warfare agent and biological toxin-induced pulmonary toxicity: could stem cells provide potential therapies?

Science.gov (United States)

Angelini, Daniel J; Dorsey, Russell M; Willis, Kristen L; Hong, Charles; Moyer, Robert A; Oyler, Jonathan; Jensen, Neil S; Salem, Harry

2013-01-01

Chemical warfare agents (CWAs) as well as biological toxins present a significant inhalation injury risk to both deployed warfighters and civilian targets of terrorist attacks. Inhalation of many CWAs and biological toxins can induce severe pulmonary toxicity leading to the development of acute lung injury (ALI) as well as acute respiratory distress syndrome (ARDS). The therapeutic options currently used to treat these conditions are very limited and mortality rates remain high. Recent evidence suggests that human stem cells may provide significant therapeutic options for ALI and ARDS in the near future. The threat posed by CWAs and biological toxins for both civilian populations and military personnel is growing, thus understanding the mechanisms of toxicity and potential therapies is critical. This review will outline the pulmonary toxic effects of some of the most common CWAs and biological toxins as well as the potential role of stem cells in treating these types of toxic lung injuries.

Computational Approaches to Chemical Hazard Assessment

Science.gov (United States)

Luechtefeld, Thomas; Hartung, Thomas

2018-01-01

Summary Computational prediction of toxicity has reached new heights as a result of decades of growth in the magnitude and diversity of biological data. Public packages for statistics and machine learning make model creation faster. New theory in machine learning and cheminformatics enables integration of chemical structure, toxicogenomics, simulated and physical data in the prediction of chemical health hazards, and other toxicological information. Our earlier publications have characterized a toxicological dataset of unprecedented scale resulting from the European REACH legislation (Registration Evaluation Authorisation and Restriction of Chemicals). These publications dove into potential use cases for regulatory data and some models for exploiting this data. This article analyzes the options for the identification and categorization of chemicals, moves on to the derivation of descriptive features for chemicals, discusses different kinds of targets modeled in computational toxicology, and ends with a high-level perspective of the algorithms used to create computational toxicology models. PMID:29101769

Emerging systems biology approaches in nanotoxicology: Towards a mechanism-based understanding of nanomaterial hazard and risk

Energy Technology Data Exchange (ETDEWEB)

Costa, Pedro M.; Fadeel, Bengt, E-mail: Bengt.Fadeel@ki.se

2016-05-15

Engineered nanomaterials are being developed for a variety of technological applications. However, the increasing use of nanomaterials in society has led to concerns about their potential adverse effects on human health and the environment. During the first decade of nanotoxicological research, the realization has emerged that effective risk assessment of the multitudes of new nanomaterials would benefit from a comprehensive understanding of their toxicological mechanisms, which is difficult to achieve with traditional, low-throughput, single end-point oriented approaches. Therefore, systems biology approaches are being progressively applied within the nano(eco)toxicological sciences. This novel paradigm implies that the study of biological systems should be integrative resulting in quantitative and predictive models of nanomaterial behaviour in a biological system. To this end, global ‘omics’ approaches with which to assess changes in genes, proteins, metabolites, etc. are deployed allowing for computational modelling of the biological effects of nanomaterials. Here, we highlight omics and systems biology studies in nanotoxicology, aiming towards the implementation of a systems nanotoxicology and mechanism-based risk assessment of nanomaterials. - Highlights: • Systems nanotoxicology is a multi-disciplinary approach to quantitative modelling. • Transcriptomics, proteomics and metabolomics remain the most common methods. • Global “omics” techniques should be coupled to computational modelling approaches. • The discovery of nano-specific toxicity pathways and biomarkers is a prioritized goal. • Overall, experimental nanosafety research must endeavour reproducibility and relevance.

Emerging systems biology approaches in nanotoxicology: Towards a mechanism-based understanding of nanomaterial hazard and risk

International Nuclear Information System (INIS)

Costa, Pedro M.; Fadeel, Bengt

2016-01-01

Engineered nanomaterials are being developed for a variety of technological applications. However, the increasing use of nanomaterials in society has led to concerns about their potential adverse effects on human health and the environment. During the first decade of nanotoxicological research, the realization has emerged that effective risk assessment of the multitudes of new nanomaterials would benefit from a comprehensive understanding of their toxicological mechanisms, which is difficult to achieve with traditional, low-throughput, single end-point oriented approaches. Therefore, systems biology approaches are being progressively applied within the nano(eco)toxicological sciences. This novel paradigm implies that the study of biological systems should be integrative resulting in quantitative and predictive models of nanomaterial behaviour in a biological system. To this end, global ‘omics’ approaches with which to assess changes in genes, proteins, metabolites, etc. are deployed allowing for computational modelling of the biological effects of nanomaterials. Here, we highlight omics and systems biology studies in nanotoxicology, aiming towards the implementation of a systems nanotoxicology and mechanism-based risk assessment of nanomaterials. - Highlights: • Systems nanotoxicology is a multi-disciplinary approach to quantitative modelling. • Transcriptomics, proteomics and metabolomics remain the most common methods. • Global “omics” techniques should be coupled to computational modelling approaches. • The discovery of nano-specific toxicity pathways and biomarkers is a prioritized goal. • Overall, experimental nanosafety research must endeavour reproducibility and relevance.

Trace element content of vegetables grown in the victorian goldfields: characterization of a potential hazard

International Nuclear Information System (INIS)

Harvey, G.; Dowling, K.; Waldron, H.; Garnett, D.

2003-01-01

Plants take-up trace elements essential to healthy growth, but if metal accumulation is excessive, harmful effects are noted in the plant and potentially in the organisms that feed on them. Central Victoria has a rich gold mining heritage, and as such, much of the landscape has been disturbed by the addition of mine waste material, providing an abundant source of metals in a mobile environment. A biogeochemical survey was conducted to evaluate the trace element content of backyard vegetable gardens in the gold field region and the trace element accumulation in commonly grown vegetables. Vegetable (n150) and soil (n59) samples were analysed by instrumental neutron activation analysis. Results indicate that vegetables grown in the central Victorian goldfields have only slightly elevated trace element content. Some exceptions exist, specifically for silverbeet, but the hazard potential is minimal

Regulatory Requirements to Combat Illicit Trafficking of Hazardous Materials

International Nuclear Information System (INIS)

Hussein, A.Z.; Zakaria, Kh.M.

2011-01-01

Since more than a decade illicit Trafficking of hazardous ( CBRNE), materials ( chemical, biological, radiological, nuclear and explosive ) has been identified as a key threat in national, regional, inter regional and international strategies. An Effective response to hazardous materials (CBRNE) risk and threat were realized to require a very high level of cooperation and coordination between various governments and their responsible organizations and authorities of regional and international partner. While improper policy of actions may easily be exploited by non- state members to (CBRNE) trafficking which may lead to develop weapon of mass destruction (WMD). Such strategy are of paramount important between all levels of the states and among regional agreements through comprehensive tailored assistance packages (e.g. export control, illicit trafficking of hazardous materials, redirection of scientist, emergency planning, crisis response safety and security culture. Capacity building, action plans and instruments for stability are necessary actions for efficient combating against illicit trafficking of hazardous materials. Regarding the needs of assessment phase, assistance must be based on data collection, analysis and prioritization of implanting the regulatory controls. Several activities have to be conducted to reduce CBRNE threat. The one- by- one approach, covering either nuclear and radioactive or chemical or biological materials has to be implanted on the country basis performance to mitigate CBRNE hazardous risk. On several consequent phases of intervention dealing with CBRNE risk mitigation the country has to establish a network of local, regional and international capabilities. Such network is setting up the mechanism for the country needs identifications, the guidelines for data collection, for data platform maintenance and update, the data assessment and the competent and operative organizations. This network will be to strengthen the long - term

Environmental hazards from natural hydrocarbons seepage: Integrated classification of risk from sediment chemistry, bioavailability and biomarkers responses in sentinel species

International Nuclear Information System (INIS)

Benedetti, Maura; Gorbi, Stefania; Fattorini, Daniele; D'Errico, Giuseppe; Piva, Francesco; Pacitti, Davide; Regoli, Francesco

2014-01-01

Potential effects of natural emissions of hydrocarbons in the marine environment have been poorly investigated. In this study, a multidisciplinary weight of evidence (WOE) study was carried out on a shallow seepage, integrating sediment chemistry with bioavailability and onset of subcellular responses (biomarkers) in caged eels and mussels. Results from different lines of evidence (LOEs) were elaborated within a quantitative WOE model which, based on logical flowcharts, provide synthetic indices of hazard for each LOE, before their integration in a quantitative risk assessment. Evaluations of different LOEs were not always in accordance and their overall elaboration summarized as Moderate the risk in the seepage area. This study provided first evidence of biological effects in organisms exposed to natural hydrocarbon emissions, confirming the limit of chemical characterization as stand-alone criteria for environmental quality assessment and the utility of multidisciplinary investigations to determine the good environmental status as required by Environmental Directives. -- Highlights: • Hazards from natural seepage were evaluated through a multidisciplinary WOE study. • Caged eels and mussels were chosen as bioindicator organisms. • Evaluations obtained from various LOEs were not always in accordance. • Biological effects of natural hydrocarbons release were demonstrated. • WOE approach could discriminate different levels of hazard in low impacted conditions. -- A multidisciplinary WOE study in a shallow coastal seepage summarized a Moderate level of risk based on integration of sediment chemistry with biological effects in caged organisms

Potential hazards of toxic metals found in toothpastes commonly used in Nigeria.

Science.gov (United States)

Orisakwe, Orish Ebere; Okolo, Kenneth Obinna; Igweze, Zelinjo Nkeiruka; Ajaezi, Godwin Chukwuebuka; Udowelle, Nnaemeka Arinze

2016-01-01

Toothpastes have multi-functional configurations as oral care products. They can however constitute a pos- sible source, amongst others, of toxic metal exposure in public health. Indeed, the public health impact of personal hygiene and consumer products is largely unknown. To determine the level of toxic metals (lead, cadmium, cobalt, chromium, nickel) in toothpastes available in Nigeria, (home produced and imported), and assess the potential risk to the people. The samples of toothpastes commonly used in Nigeria were tested. Using a market basket protocol thirty five different brands of toothpaste were used. Samples were digest by addition of 10 mL mixture of conc. nitric and hydrochloric acids (HCl:HNO(3), 3:1), followed by heating to dryness. 20 mL deionized water was added, stirred and filtered. The filtrate was made up in standard volumetric flask and lead, cadmium, chromium, cobalt and nickel concentrations were determined using the atomic absorption spectrophotometry 205A. The daily intake of metals and target hazard quotient (THQ) were then calculated. Pepsodent and Flodent had the highest levels of lead at respectively 23.575 and 18.092 mg/kg while Colgate Herbal had the highest nickel of 18.535 mg/kg. The daily intake estimates of all imported toothpaste samples were below the stated upper limits (UL). All target hazard quotients were also found to be below one. Although the UL, THQ and daily intake rates were all normal, the high levels of lead in some of the tooth- pastes an important concern to public health suggesting that pre-marketing safety studies of toothpastes may be worthwhile for the regulatory authorities.

E. Biological effects of radiation on man

International Nuclear Information System (INIS)

1976-01-01

This report firstly summarises information on the biological hazards of radiation and their relation to radiation dose, and hence estimates the biological risks associated with nuclear power production. Secondly, it describes the basis and present status of radiation protection standards in the nuclear power industry

The environmental and medical geochemistry of potentially hazardous materials produced by disasters

Science.gov (United States)

Plumlee, Geoffrey S.; Morman, Suzette A.; Meeker, G.P.; Hoefen, Todd M.; Hageman, Philip L.; Wolf, Ruth E.

2014-01-01

Many natural or human-caused disasters release potentially hazardous materials (HM) that may pose threats to the environment and health of exposed humans, wildlife, and livestock. This chapter summarizes the environmentally and toxicologically significant physical, mineralogical, and geochemical characteristics of materials produced by a wide variety of recent disasters, such as volcanic eruptions, hurricanes and extreme storms, spills of mining/mineral-processing wastes or coal extraction by-products, and the 2001 attacks on and collapse of the World Trade Center towers. In describing these characteristics, this chapter also illustrates the important roles that geochemists and other earth scientists can play in environmental disaster response and preparedness. In addition to characterizing in detail the physical, chemical, and microbial makeup of HM generated by the disasters, these roles also include (1) identifying and discriminating potential multiple sources of the materials; (2) monitoring, mapping, and modeling dispersal and evolution of the materials in the environment; (3) understanding how the materials are modified by environmental processes; (4) identifying key characteristics and processes that influence the materials' toxicity to exposed humans and ecosystems; (5) estimating shifts away from predisaster environmental baseline conditions; and (6) using geochemical insights learned from past disasters to help estimate, prepare for, and increase societal resilience to the environmental and related health impacts of future disasters.

Chemical incidents resulted in hazardous substances releases in the context of human health hazards.

OpenAIRE

Palaszewska-Tkacz, Anna; Czerczak, Sławomir; Konieczko, Katarzyna

2017-01-01

Objectives: The research purpose was to analyze data concerning chemical incidents in Poland collected in 1999–2009 in terms of health hazards. Material and Methods: The data was obtained, using multimodal information technology (IT) system, from chemical incidents reports prepared by rescuers at the scene. The final analysis covered sudden events associated with uncontrolled release of hazardous chemical substances or mixtures, which may potentially lead to human exposure. Releases of uniden...

Robotics and artificial intelligence for hazardous environments

International Nuclear Information System (INIS)

Spelt, P.F.

1993-01-01

In our technological society, hazardous materials including toxic chemicals, flammable, explosive, and radioactive substances, and biological agents, are used and handled routinely. Each year, many workers who handle these substances are accidently contaminated, in some cases resulting in injury, death, or chronic disabilities. If these hazardous materials could be handled remotely, either with a teleoperated robot (operated by a worker in a safe location) or by an autonomous robot, then human suffering and economic costs of accidental exposures could be dramatically reduced. At present, it is still difficult for commercial robotic technology to completely replace humans involved in performing complex work tasks in hazardous environments. The robotics efforts at the Center for Engineering Systems Advanced Research represent a significant effort at contributing to the advancement of robotics for use in hazardous environments. While this effort is very broad-based, ranging from dextrous manipulation to mobility and integrated sensing, the technical portion of this paper will focus on machine learning and the high-level decision making needed for autonomous robotics

Fire hazards analysis for solid waste burial grounds

International Nuclear Information System (INIS)

McDonald, K.M.

1995-01-01

This document comprises the fire hazards analysis for the solid waste burial grounds, including TRU trenches, low-level burial grounds, radioactive mixed waste trenches, etc. It analyzes fire potential, and fire damage potential for these facilities. Fire scenarios may be utilized in future safety analysis work, or for increasing the understanding of where hazards may exist in the present operation

A critical review of the current knowledge regarding the biological impact of nanocellulose.

Science.gov (United States)

Endes, C; Camarero-Espinosa, S; Mueller, S; Foster, E J; Petri-Fink, A; Rothen-Rutishauser, B; Weder, C; Clift, M J D

2016-12-01

Several forms of nanocellulose, notably cellulose nanocrystals and nanofibrillated cellulose, exhibit attractive property matrices and are potentially useful for a large number of industrial applications. These include the paper and cardboard industry, use as reinforcing filler in polymer composites, basis for low-density foams, additive in adhesives and paints, as well as a wide variety of food, hygiene, cosmetic, and medical products. Although the commercial exploitation of nanocellulose has already commenced, little is known as to the potential biological impact of nanocellulose, particularly in its raw form. This review provides a comprehensive and critical review of the current state of knowledge of nanocellulose in this format. Overall, the data seems to suggest that when investigated under realistic doses and exposure scenarios, nanocellulose has a limited associated toxic potential, albeit certain forms of nanocellulose can be associated with more hazardous biological behavior due to their specific physical characteristics.

Catalytic Destruction of a Surrogate Organic Hazardous Air Pollutant as a Potential Co-benefit for Coal-fired Selective Catalyst Reduction Systems

Science.gov (United States)

Catalytic destruction of benzene (C6H6), a surrogate for organic hazardous air pollutants (HAPs) produced from coal combustion, was investigated using a commercial selective catalytic reduction (SCR) catalyst for evaluating the potential co-benefit of the SCR technology for reduc...

An accurate evaluation of the potential hazardous impact of Polycyclic Aromatic Hydrocarbons in biochars

Science.gov (United States)

María De la Rosa, José; Sánchez-Martín, Águeda; Villaverde-Capellán, Jaime; Madrid, Fernando; Paneque, Marina; Knicker, Heike

2017-04-01

Biochar may act as a soil conditioner, enhancing plant growth by supplying and retaining nutrients and by providing other services such as improving soil physical, chemical and biological properties. Feedstock properties and production conditions drive the nature of produced biochars [1]. Special attention have to be paid to their content of polycyclic aromatic hydrocarbons (PAHs), which are persistent organic pollutants formed during biochar production due to incomplete combustion (pyrolysis step) [2]. These PAHs may enter the environment when the biochar is applied as soil conditioner. Therefore, the intention of this study was to test a potential hazardous impact of biochar amendment due to the presence of PAHs. In order to find a relationship between pyrolysis conditions, feedstock and abundance of PAHs, four biochars produced from different feedstock were analyzed. Three biochars were produced by technical pyrolysis (500-600 °C; 20 min) from wood, paper sludge and sewage sludge respectively (samples B1, B2 and B3). The fourth biochar sample derived from old grapevine wood by using the traditional carbonization method in kilns (kiln-stack wood biochar; B4). A detailed characterization of physical and chemical properties of these samples can be found in De la Rosa et al, [3]. Two different PAHs extraction techniques were applied to evaluate the total and available PAHs content of the biochars. They consisted in an extraction with toluene using a Soxhlet extractor and a non-exhaustive extraction with Cyclodextrins (CDs). Chromatographic and mass spectrometric conditions applied are described in [1]. Total PAHs yielded between 3 ppm (B3) and 7 (B4) ppm. The production of biochar by using traditional kilns instead of controlled pyrolysis, increased significantly the total PAHs levels. No direct relationship was found between the total PAHs and the PAHs extracted by CDs, which can be considered as the bioavailable fraction. This parameter should replace the total

The potential of standards-based agriculture biology as an alternative to traditional biology in California

Science.gov (United States)

Sellu, George Sahr

schools. Thoron & Meyer (2011) suggested that research into the contribution of integrated science courses toward higher test scores yielded mixed results. This finding may have been due in part to the fact that integrated science courses only incorporate select topics into agriculture education courses. In California, however, agriculture educators have developed standards-based courses such as Agriculture Biology (AgBio) that cover the same content standards as core traditional courses such as traditional biology. Students in both AgBio and traditional biology take the same standardized biology test. This is the first time there has been an opportunity for a fair comparison and a uniform metric for an agriscience course such as AgBio to be directly compared to traditional biology. This study will examine whether there are differences between AgBio and traditional biology with regard to standardized test scores in biology. Furthermore, the study examines differences in perception between teachers and students regarding teaching and learning activities associated with higher achievement in science. The findings of the study could provide a basis for presenting AgBio as a potential alternative to traditional biology. The findings of this study suggest that there are no differences between AgBio and traditional biology students with regard to standardized biology test scores. Additionally, the findings indicate that co-curricular activities in AgBio could contribute higher student achievement in biology. However, further research is required to identify specific activities in AgBio that contribute to higher achievement in science.

Probing nanomechanical interaction at the interface between biological membrane and potentially toxic chemical.

Science.gov (United States)

Lim, Chanoong; Park, Sohee; Park, Jinwoo; Ko, Jina; Lee, Dong Woog; Hwang, Dong Soo

2018-04-12

Various xenobiotics interact with biological membranes, and precise evaluations of the molecular interactions between them are essential to foresee the toxicity and bioavailability of existing or newly synthesized molecules. In this study, surface forces apparatus (SFA) measurement and Langmuir trough based tensiometry are performed to reveal nanomechanical interaction mechanisms between potential toxicants and biological membranes for ex vivo toxicity evaluation. As a toxicant, polyhexamethylene guanidine (PHMG) was selected because PHMG containing humidifier disinfectant and Vodka caused lots of victims in both S. Korea and Russia, respectively, due to the lack of holistic toxicity evaluation of PHMG. Here, we measured strong attraction (Wad ∼4.2 mJ/m 2 ) between PHMG and head group of biological membranes while no detectable adhesion force between the head group and control molecules was measured. Moreover, significant changes in π-A isotherm of 1,2-Dipalmitoyl-sn-glycero-3-phosphatidylcholine (DPPC) monolayers were measured upon PHMG adsorption. These results indicate PHMG strongly binds to hydrophilic group of lipid membranes and alters the structural and phase behavior of them. More importantly, complementary utilization of SFA and Langmuir trough techniques are found to be useful to predict the potential toxicity of a chemical by evaluating the molecular interaction with biological membranes, the primary protective barrier for living organisms. Copyright © 2018 Elsevier B.V. All rights reserved.

Biological activities and biomedical potential of sea cucumber (Stichopus japonicus: a review

Directory of Open Access Journals (Sweden)

Gun-Woo Oh

2017-11-01

Full Text Available Abstract Members of the phylum Echinodermata, commonly known as echinoderms, are exclusively marine invertebrates. Among the Echinodermata, sea cucumber belongs to the family Holothuroidea. The sea cucumber Stichopus (Apostichous japonicus (Selenka is an invertebrate animal inhabiting the coastal sea around Korean, Japan, China, and Russia. Sea cucumber has a significant commercial value, because it contains valuable nutrients such as vitamins and minerals. They possess a number of distinctive biologically and pharmacologically important compounds. In particular, the body wall of sea cucumber is a major edible part. It consists of peptide, collagen, gelatin, polysaccharide, and saponin, which possess several biological activities such as anti-cancer, anti-coagulation, anti-oxidation, and anti-osteoclastogenesis. Furthermore, the regenerative capacity of sea cucumber makes it a medically important organism. This review presents the various biological activities and biomedical potential of sea cucumber S. japonicus.

Carbon Structure Hazard Control

Science.gov (United States)

Yoder, Tommy; Greene, Ben; Porter, Alan

2015-01-01

Carbon composite structures are widely used in virtually all advanced technology industries for a multitude of applications. The high strength-to-weight ratio and resistance to aggressive service environments make them highly desirable. Automotive, aerospace, and petroleum industries extensively use, and will continue to use, this enabling technology. As a result of this broad range of use, field and test personnel are increasingly exposed to hazards associated with these structures. No single published document exists to address the hazards and make recommendations for the hazard controls required for the different exposure possibilities from damaged structures including airborne fibers, fly, and dust. The potential for personnel exposure varies depending on the application or manipulation of the structure. The effect of exposure to carbon hazards is not limited to personnel, protection of electronics and mechanical equipment must be considered as well. The various exposure opportunities defined in this document include pre-manufacturing fly and dust, the cured structure, manufacturing/machining, post-event cleanup, and post-event test and/or evaluation. Hazard control is defined as it is applicable or applied for the specific exposure opportunity. The carbon exposure hazard includes fly, dust, fiber (cured/uncured), and matrix vapor/thermal decomposition products. By using the recommendations in this document, a high level of confidence can be assured for the protection of personnel and equipment.

The underground diposal of hazardous wastes - necessity, possibilities and limitations

International Nuclear Information System (INIS)

Herrmann, A.G.; Brumsack, H.J.; Heinrichs, H.

1985-01-01

The natural geochemical cycles of many elements in the atmosphere, hydrosphere, and pedosphere have been changed during the past decades by anthropogenic activities. To put a stop to this development, a drastic reduction of the uncontrolled dispersal of potentially hazardous substances into our environment is necessary, compelling the need for the safe disposal of radioactive and nonradioactive hazardous wastes far away from the biosphere. The amount of potentially hazardous waste produced annually in West Germany is larger by a factor of at least 20 than the volume of hazardous material for which suitable underground disposal sites are planned and available at present. (orig.)

Hazard Assessment of Chemical Air Contaminants Measured in Residences

Energy Technology Data Exchange (ETDEWEB)

Logue, J.M.; McKone, T.E.; Sherman, M. H.; Singer, B.C.

2010-05-10

Identifying air pollutants that pose a potential hazard indoors can facilitate exposure mitigation. In this study, we compiled summary results from 77 published studies reporting measurements of chemical pollutants in residences in the United States and in countries with similar lifestyles. These data were used to calculate representative mid-range and upper bound concentrations relevant to chronic exposures for 267 pollutants and representative peak concentrations relevant to acute exposures for 5 activity-associated pollutants. Representative concentrations are compared to available chronic and acute health standards for 97 pollutants. Fifteen pollutants appear to exceed chronic health standards in a large fraction of homes. Nine other pollutants are identified as potential chronic health hazards in a substantial minority of homes and an additional nine are identified as potential hazards in a very small percentage of homes. Nine pollutants are identified as priority hazards based on the robustness of measured concentration data and the fraction of residences that appear to be impacted: acetaldehyde; acrolein; benzene; 1,3-butadiene; 1,4-dichlorobenzene; formaldehyde; naphthalene; nitrogen dioxide; and PM{sub 2.5}. Activity-based emissions are shown to pose potential acute health hazards for PM{sub 2.5}, formaldehyde, CO, chloroform, and NO{sub 2}.

Waste Encapsulation and Storage Facility (WESF) Hazards Assessment

International Nuclear Information System (INIS)

COVEY, L.I.

2000-01-01

This report documents the hazards assessment for the Waste Encapsulation and Storage Facility (WESF) located on the U.S. Department of Energy (DOE) Hanford Site. This hazards assessment was conducted to provide the emergency planning technical basis for WESF. DOE Orders require an emergency planning hazards assessment for each facility that has the potential to reach or exceed the lowest level emergency classification

Bioprocessing of low-level radioactive and mixed hazard wastes

International Nuclear Information System (INIS)

Stoner, D.L.

1990-01-01

Biologically-based treatment technologies are currently being developed at the Idaho National Engineering Laboratory (INEL) to aid in volume reduction and/or reclassification of low-level radioactive and mixed hazardous wastes prior to processing for disposal. The approaches taken to treat low-level radioactive and mixed wastes will reflect the physical (e.g., liquid, solid, slurry) and chemical (inorganic and/or organic) nature of the waste material being processed. Bioprocessing utilizes the diverse metabolic and biochemical characteristics of microorganisms. The application of bioadsorption and bioflocculation to reduce the volume of low-level radioactive waste are strategies comparable to the use of ion-exchange resins and coagulants that are currently used in waste reduction processes. Mixed hazardous waste would require organic as well as radionuclide treatment processes. Biodegradation of organic wastes or bioemulsification could be used in conjunction with radioisotope bioadsorption methods to treat mixed hazardous radioactive wastes. The degradation of the organic constituents of mixed wastes can be considered an alternative to incineration, while the use of bioemulsification may simply be used as a means to separate inorganic and organics to enable reclassification of wastes. The proposed technology base for the biological treatment of low-level radioactive and mixed hazardous waste has been established. Biodegradation of a variety of organic compounds that are typically found in mixed hazardous wastes has been demonstrated, degradative pathways determined and the nutritional requirements of the microorganisms are understood. Accumulation, adsorption and concentration of heavy and transition metal species and transuranics by microorganisms is widely recognized. Work at the INEL focuses on the application of demonstrated microbial transformations to process development

Marine and land active-source seismic investigation of geothermal potential, tectonic structure, and earthquake hazards in Pyramid Lake, Nevada

Energy Technology Data Exchange (ETDEWEB)

Eisses, A.; Kell, A.; Kent, G. [UNR; Driscoll, N. [UCSD; Karlin, R.; Baskin, R. [USGS; Louie, J. [UNR; Pullammanappallil, S. [Optim

2016-08-01

Amy Eisses, Annie M. Kell, Graham Kent, Neal W. Driscoll, Robert E. Karlin, Robert L. Baskin, John N. Louie, Kenneth D. Smith, Sathish Pullammanappallil, 2011, Marine and land active-source seismic investigation of geothermal potential, tectonic structure, and earthquake hazards in Pyramid Lake, Nevada: presented at American Geophysical Union Fall Meeting, San Francisco, Dec. 5-9, abstract NS14A-08.

Potential postwildfire debris-flow hazards: a prewildfire evaluation for the Sandia and Manzano Mountains and surrounding areas, central New Mexico

Science.gov (United States)

Tillery, Anne C.; Haas, Jessica R.; Miller, Lara W.; Scott, Joe H.; Thompson, Matthew P.

2014-01-01

Wildfire can drastically increase the probability of debris flows, a potentially hazardous and destructive form of mass wasting, in landscapes that have otherwise been stable throughout recent history. Although there is no way to know the exact location, extent, and severity of wildfire, or the subsequent rainfall intensity and duration before it happens, probabilities of fire and debris-flow occurrence for different locations can be estimated with geospatial analysis and modeling efforts. The purpose of this report is to provide information on which watersheds might constitute the most serious, potential, debris-flow hazards in the event of a large-scale wildfire and subsequent rainfall in the Sandia and Manzano Mountains. Potential probabilities and estimated volumes of postwildfire debris flows in the unburned Sandia and Manzano Mountains and surrounding areas were estimated using empirical debris-flow models developed by the U.S. Geological Survey in combination with fire behavior and burn probability models developed by the U.S. Department of Agriculture Forest Service. The locations of the greatest debris-flow hazards correlate with the areas of steepest slopes and simulated crown-fire behavior. The four subbasins with the highest computed debris-flow probabilities (greater than 98 percent) were all in the Manzano Mountains, two flowing east and two flowing west. Volumes in sixteen subbasins were greater than 50,000 square meters and most of these were in the central Manzanos and the western facing slopes of the Sandias. Five subbasins on the west-facing slopes of the Sandia Mountains, four of which have downstream reaches that lead into the outskirts of the City of Albuquerque, are among subbasins in the 98th percentile of integrated relative debris-flow hazard rankings. The bulk of the remaining subbasins in the 98th percentile of integrated relative debris-flow hazard rankings are located along the highest and steepest slopes of the Manzano Mountains. One

Hazard-ranking of agricultural pesticides for chronic health effects in Yuma County, Arizona.

Science.gov (United States)

Sugeng, Anastasia J; Beamer, Paloma I; Lutz, Eric A; Rosales, Cecilia B

2013-10-01

With thousands of pesticides registered by the United States Environmental Protection Agency, it not feasible to sample for all pesticides applied in agricultural communities. Hazard-ranking pesticides based on use, toxicity, and exposure potential can help prioritize community-specific pesticide hazards. This study applied hazard-ranking schemes for cancer, endocrine disruption, and reproductive/developmental toxicity in Yuma County, Arizona. An existing cancer hazard-ranking scheme was modified, and novel schemes for endocrine disruption and reproductive/developmental toxicity were developed to rank pesticide hazards. The hazard-ranking schemes accounted for pesticide use, toxicity, and exposure potential based on chemical properties of each pesticide. Pesticides were ranked as hazards with respect to each health effect, as well as overall chronic health effects. The highest hazard-ranked pesticides for overall chronic health effects were maneb, metam-sodium, trifluralin, pronamide, and bifenthrin. The relative pesticide rankings were unique for each health effect. The highest hazard-ranked pesticides differed from those most heavily applied, as well as from those previously detected in Yuma homes over a decade ago. The most hazardous pesticides for cancer in Yuma County, Arizona were also different from a previous hazard-ranking applied in California. Hazard-ranking schemes that take into account pesticide use, toxicity, and exposure potential can help prioritize pesticides of greatest health risk in agricultural communities. This study is the first to provide pesticide hazard-rankings for endocrine disruption and reproductive/developmental toxicity based on use, toxicity, and exposure potential. These hazard-ranking schemes can be applied to other agricultural communities for prioritizing community-specific pesticide hazards to target decreasing health risk. Copyright © 2013 Elsevier B.V. All rights reserved.

Hazard-Ranking of Agricultural Pesticides for Chronic Health Effects in Yuma County, Arizona

Science.gov (United States)

Sugeng, Anastasia J.; Beamer, Paloma I.; Lutz, Eric A.; Rosales, Cecilia B.

2013-01-01

With thousands of pesticides registered by the United States Environmental Protection Agency, it not feasible to sample for all pesticides applied in agricultural communities. Hazard-ranking pesticides based on use, toxicity, and exposure potential can help prioritize community-specific pesticide hazards. This study applied hazard-ranking schemes for cancer, endocrine disruption, and reproductive/developmental toxicity in Yuma County, Arizona. An existing cancer hazard-ranking scheme was modified, and novel schemes for endocrine disruption and reproductive/developmental toxicity were developed to rank pesticide hazards. The hazard-ranking schemes accounted for pesticide use, toxicity, and exposure potential based on chemical properties of each pesticide. Pesticides were ranked as hazards with respect to each health effect, as well as overall chronic health effects. The highest hazard-ranked pesticides for overall chronic health effects were maneb, metam sodium, trifluralin, pronamide, and bifenthrin. The relative pesticide rankings were unique for each health effect. The highest hazard-ranked pesticides differed from those most heavily applied, as well as from those previously detected in Yuma homes over a decade ago. The most hazardous pesticides for cancer in Yuma County, Arizona were also different from a previous hazard-ranking applied in California. Hazard-ranking schemes that take into account pesticide use, toxicity, and exposure potential can help prioritize pesticides of greatest health risk in agricultural communities. This study is the first to provide pesticide hazard-rankings for endocrine disruption and reproductive/developmental toxicity based on use, toxicity, and exposure potential. These hazard-ranking schemes can be applied to other agricultural communities for prioritizing community-specific pesticide hazards to target decreasing health risk. PMID:23783270

Assessment of Debris Flow Potential Hazardous Zones Using Numerical Models in the Mountain Foothills of Santiago, Chile

Science.gov (United States)

Celis, C.; Sepulveda, S. A.; Castruccio, A.; Lara, M.

2017-12-01

Debris and mudflows are some of the main geological hazards in the mountain foothills of Central Chile. The risk of flows triggered in the basins of ravines that drain the Andean frontal range into the capital city, Santiago, increases with time due to accelerated urban expansion. Susceptibility assessments were made by several authors to detect the main active ravines in the area. Macul and San Ramon ravines have a high to medium debris flow susceptibility, whereas Lo Cañas, Apoquindo and Las Vizcachas ravines have a medium to low debris flow susceptibility. This study emphasizes in delimiting the potential hazardous zones using the numerical simulation program RAMMS-Debris Flows with the Voellmy model approach, and the debris-flow model LAHARZ. This is carried out by back-calculating the frictional parameters in the depositional zone with a known event as the debris and mudflows in Macul and San Ramon ravines, on May 3rd, 1993, for the RAMMS approach. In the same scenario, we calibrate the coefficients to match conditions of the mountain foothills of Santiago for the LAHARZ model. We use the information obtained for every main ravine in the study area, mainly for the similarity in slopes and material transported. Simulations were made for the worst-case scenario, caused by the combination of intense rainfall storms, a high 0°C isotherm level and material availability in the basins where the flows are triggered. The results show that the runout distances are well simulated, therefore a debris-flow hazard map could be developed with these models. Correlation issues concerning the run-up, deposit thickness and transversal areas are reported. Hence, the models do not represent entirely the complexity of the phenomenon, but they are a reliable approximation for preliminary hazard maps.

Health and safety information program for hazardous materials

International Nuclear Information System (INIS)

O'Brien, M.P.; Fallon, N.J.; Kuehner, A.V.

1979-01-01

The system is used as a management tool in several safety and health programs. It is used to: trace the use of hazardous materials and to determine monitoring needs; inform the occupational physician of the potential health problems associated with materials ordered by a given individual; inform the fire and rescue group of hazardous materials in a given building; provide waste disposal recommendations to the hazardous waste management group; assist the hazardous materials shipping coordinator in identifying materials which are regulated by the Department of Transportation; and guide management decisions in the area of recognizing and rectifying unsafe conditions. The information system has been expanded from a manual effort to provide a brief description of health hazards of chemicals used at the lab to a computerized health and safety information system which serves the needs of all personnel who may encounter the material in the course of their work. The system has been designed to provide information needed to control the potential problems associated with a hazardous material up to the time that it is consumed in a given operation or is sent to the waste disposal facility

Risk-based consequences of extreme natural hazard processes in mountain regions - Multi-hazard analysis in Tyrol (Austria)

Science.gov (United States)

Huttenlau, Matthias; Stötter, Johann

2010-05-01

Reinsurance companies are stating a high increase in natural hazard related losses, both insured and economic losses, within the last decades on a global scale. This ongoing trend can be described as a product of the dynamic in the natural and in the anthroposphere. To analyze the potential impact of natural hazard process to a certain insurance portfolio or to the society in general, reinsurance companies or risk management consultants have developed loss models. However, those models are generally not fitting the scale dependent demand on regional scales like it is appropriate (i) for analyses on the scale of a specific province or (ii) for portfolio analyses of regional insurance companies. Moreover, the scientific basis of most of the models is not transparent documented and therefore scientific evaluations concerning the methodology concepts are not possible (black box). This is contrary to the scientific principles of transparency and traceability. Especially in mountain regions like the European Alps with their inherent (i) specific characteristic on small scales, (ii) the relative high process dynamics in general, (iii) the occurrence of gravitative mass movements which are related to high relief energy and thus only exists in mountain regions, (iv) the small proportion of the area of permanent settlement on the overall area, (v) the high value concentration in the valley floors, (vi) the exposition of important infrastructures and lifelines, and others, analyses must consider these circumstances adequately. Therefore, risk-based analyses are methodically estimating the potential consequences of hazard process on the built environment standardized with the risk components (i) hazard, (ii) elements at risk, and (iii) vulnerability. However, most research and progress have been made in the field of hazard analyses, whereas the other both components are not developed accordingly. Since these three general components are influencing factors without any

Potential postwildfire debris-flow hazards - a prewildfire evaluation for the Sandia and Manzano Mountains and surrounding areas, central New Mexico

Science.gov (United States)

Anne C. Tillery; Jessica R. Haas; Lara W. Miller; Joe H. Scott; Matthew P. Thompson

2014-01-01

Wildfire can drastically increase the probability of debris flows, a potentially hazardous and destructive form of mass wasting, in landscapes that have otherwise been stable throughout recent history. Although there is no way to know the exact location, extent, and severity of wildfire, or the subsequent rainfall intensity and duration before it happens, probabilities...

Green Jobs: Definition and Method of Appraisal of Chemical and Biological Risks.

Science.gov (United States)

Cheneval, Erwan; Busque, Marc-Antoine; Ostiguy, Claude; Lavoie, Jacques; Bourbonnais, Robert; Labrèche, France; Bakhiyi, Bouchra; Zayed, Joseph

2016-04-01

In the wake of sustainable development, green jobs are developing rapidly, changing the work environment. However a green job is not automatically a safe job. The aim of the study was to define green jobs, and to establish a preliminary risk assessment of chemical substances and biological agents for workers in Quebec. An operational definition was developed, along with criteria and sustainable development principles to discriminate green jobs from regular jobs. The potential toxicity or hazard associated with their chemical and biological exposures was assessed, and the workers' exposure appraised using an expert assessment method. A control banding approach was then used to assess risks for workers in selected green jobs. A double entry model allowed us to set priorities in terms of chemical or biological risk. Among jobs that present the highest risk potential, several are related to waste management. The developed method is flexible and could be adapted to better appraise the risks that workers are facing or to propose control measures. © The Author 2015. Published by Oxford University Press on behalf of the British Occupational Hygiene Society.

Evaluation of potential surface rupture and review of current seismic hazards program at the Los Alamos National Laboratory. Final report

International Nuclear Information System (INIS)

1991-01-01

This report summarizes the authors review and evaluation of the existing seismic hazards program at Los Alamos National Laboratory (LANL). The report recommends that the original program be augmented with a probabilistic analysis of seismic hazards involving assignment of weighted probabilities of occurrence to all potential sources. This approach yields a more realistic evaluation of the likelihood of large earthquake occurrence particularly in regions where seismic sources may have recurrent intervals of several thousand years or more. The report reviews the locations and geomorphic expressions of identified fault lines along with the known displacements of these faults and last know occurrence of seismic activity. Faults are mapped and categorized into by their potential for actual movement. Based on geologic site characterization, recommendations are made for increased seismic monitoring; age-dating studies of faults and geomorphic features; increased use of remote sensing and aerial photography for surface mapping of faults; the development of a landslide susceptibility map; and to develop seismic design standards for all existing and proposed facilities at LANL

Hazard index for underground toxic material

International Nuclear Information System (INIS)

Smith, C.F.; Cohen, J.J.; McKone, T.E.

1980-06-01

To adequately define the problem of waste management, quantitative measures of hazard must be used. This study reviews past work in the area of hazard indices and proposes a geotoxicity hazard index for use in characterizing the hazard of toxic material buried underground. Factors included in this index are: an intrinsic toxicity factor, formulated as the volume of water required for dilution to public drinking-water levels; a persistence factor to characterize the longevity of the material, ranging from unity for stable materials to smaller values for shorter-lived materials; an availability factor that relates the transport potential for the particular material to a reference value for its naturally occurring analog; and a correction factor to accommodate the buildup of decay progeny, resulting in increased toxicity

Hazard index for underground toxic material

Energy Technology Data Exchange (ETDEWEB)

Smith, C.F.; Cohen, J.J.; McKone, T.E.

1980-06-01

To adequately define the problem of waste management, quantitative measures of hazard must be used. This study reviews past work in the area of hazard indices and proposes a geotoxicity hazard index for use in characterizing the hazard of toxic material buried underground. Factors included in this index are: an intrinsic toxicity factor, formulated as the volume of water required for dilution to public drinking-water levels; a persistence factor to characterize the longevity of the material, ranging from unity for stable materials to smaller values for shorter-lived materials; an availability factor that relates the transport potential for the particular material to a reference value for its naturally occurring analog; and a correction factor to accommodate the buildup of decay progeny, resulting in increased toxicity.

Hazard avoidance via descent images for safe landing

Science.gov (United States)

Yan, Ruicheng; Cao, Zhiguo; Zhu, Lei; Fang, Zhiwen

2013-10-01

In planetary or lunar landing missions, hazard avoidance is critical for landing safety. Therefore, it is very important to correctly detect hazards and effectively find a safe landing area during the last stage of descent. In this paper, we propose a passive sensing based HDA (hazard detection and avoidance) approach via descent images to lower the landing risk. In hazard detection stage, a statistical probability model on the basis of the hazard similarity is adopted to evaluate the image and detect hazardous areas, so that a binary hazard image can be generated. Afterwards, a safety coefficient, which jointly utilized the proportion of hazards in the local region and the inside hazard distribution, is proposed to find potential regions with less hazards in the binary hazard image. By using the safety coefficient in a coarse-to-fine procedure and combining it with the local ISD (intensity standard deviation) measure, the safe landing area is determined. The algorithm is evaluated and verified with many simulated descent downward looking images rendered from lunar orbital satellite images.

Assessment of radiation safety awareness and attitude toward biological effect of radiation for employees in nuclear workplace

International Nuclear Information System (INIS)

Youngchuay, U.; Jetawattana, S.; Toeypho, V.; Eso, J.

2016-01-01

This study demonstrated a potential relevance of data pertaining to the interaction of awareness in radiation biology and their attitude towards radiation hazards. The obtained information is useful in ascertaining the effectiveness of the ongoing radiation safety program and will be further used to determine the relationships between the radiation effective dose and cytogenetic approach in these groups of workers. (author)

Hazards analysis of TNX Large Melter-Off-Gas System

International Nuclear Information System (INIS)

Randall, C.T.

1982-03-01

Analysis of the potential safety hazards and an evaluation of the engineered safety features and administrative controls indicate that the LMOG System can be operated without undue hazard to employees or the public, or damage to equipment. The safety features provided in the facility design coupled with the planned procedural and administrative controls make the occurrence of serious accidents very improbable. A set of recommendations evolved during this analysis that was judged potentially capable of further reducing the probability of personnel injury or further mitigating the consequences of potential accidents. These recommendations concerned areas such as formic acid vapor hazards, hazard of feeding water to the melter at an uncontrolled rate, prevention of uncontrolled glass pours due to melter pressure excursions and additional interlocks. These specific suggestions were reviewed with operational and technical personnel and are being incorporated into the process. The safeguards provided by these recommendations are discussed in this report

Systems biology-guided identification of synthetic lethal gene pairs and its potential use to discover antibiotic combinations

DEFF Research Database (Denmark)

Aziz, Ramy K.; Monk, Jonathan M.; Lewis, R. M.

2015-01-01

Mathematical models of metabolism from bacterial systems biology have proven their utility across multiple fields, for example metabolic engineering, growth phenotype simulation, and biological discovery. The usefulness of the models stems from their ability to compute a link between genotype...... of metabolic models, and highlight one potential application of systems biology to drug discovery and translational medicine....

FIRE HAZARDS ANALYSIS - BUSTED BUTTE

International Nuclear Information System (INIS)

Longwell, R.; Keifer, J.; Goodin, S.

2001-01-01

The purpose of this fire hazards analysis (FHA) is to assess the risk from fire within individual fire areas at the Busted Butte Test Facility and to ascertain whether the DOE fire safety objectives are met. The objective, identified in DOE Order 420.1, Section 4.2, is to establish requirements for a comprehensive fire and related hazards protection program for facilities sufficient to minimize the potential for: (1) The occurrence of a fire related event. (2) A fire that causes an unacceptable on-site or off-site release of hazardous or radiological material that will threaten the health and safety of employees. (3) Vital DOE programs suffering unacceptable interruptions as a result of fire and related hazards. (4) Property losses from a fire and related events exceeding limits established by DOE. Critical process controls and safety class systems being damaged as a result of a fire and related events

Environmental hazard assessment of a marine mine tailings deposit site and potential implications for deep-sea mining.

Science.gov (United States)

Mestre, Nélia C; Rocha, Thiago L; Canals, Miquel; Cardoso, Cátia; Danovaro, Roberto; Dell'Anno, Antonio; Gambi, Cristina; Regoli, Francesco; Sanchez-Vidal, Anna; Bebianno, Maria João

2017-09-01

Portmán Bay is a heavily contaminated area resulting from decades of metal mine tailings disposal, and is considered a suitable shallow-water analogue to investigate the potential ecotoxicological impact of deep-sea mining. Resuspension plumes were artificially created by removing the top layer of the mine tailings deposit by bottom trawling. Mussels were deployed at three sites: i) off the mine tailings deposit area; ii) on the mine tailings deposit beyond the influence from the resuspension plumes; iii) under the influence of the artificially generated resuspension plumes. Surface sediment samples were collected at the same sites for metal analysis and ecotoxicity assessment. Metal concentrations and a battery of biomarkers (oxidative stress, metal exposure, biotransformation and oxidative damage) were measured in different mussel tissues. The environmental hazard posed by the resuspension plumes was investigated by a quantitative weight of evidence (WOE) model that integrated all the data. The resuspension of sediments loaded with metal mine tails demonstrated that chemical contaminants were released by trawling subsequently inducing ecotoxicological impact in mussels' health. Considering as sediment quality guidelines (SQGs) those indicated in Spanish action level B for the disposal of dredged material at sea, the WOE model indicates that the hazard is slight off the mine tailings deposit, moderate on the mine tailings deposit without the influence from the resuspension plumes, and major under the influence of the resuspension plumes. Portmán Bay mine tailings deposit is a by-product of sulphide mining, and despite differences in environmental setting, it can reflect the potential ecotoxic effects to marine fauna from the impact of resuspension of plumes created by deep-sea mining of polymetallic sulphides. A similar approach as in this study could be applied in other areas affected by sediment resuspension and for testing future deep-sea mining sites in

The Volcanic Hazards Assessment Support System for the Online Hazard Assessment and Risk Mitigation of Quaternary Volcanoes in the World

Directory of Open Access Journals (Sweden)

Shinji Takarada

2017-12-01

Full Text Available Volcanic hazards assessment tools are essential for risk mitigation of volcanic activities. A number of offline volcanic hazard assessment tools have been provided, but in most cases, they require relatively complex installation procedure and usage. This situation causes limited usage of volcanic hazard assessment tools among volcanologists and volcanic hazards communities. In addition, volcanic eruption chronology and detailed database of each volcano in the world are essential key information for volcanic hazard assessment, but most of them are isolated and not connected to and with each other. The Volcanic Hazard Assessment Support System aims to implement a user-friendly, WebGIS-based, open-access online system for potential hazards assessment and risk-mitigation of Quaternary volcanoes in the world. The users can get up-to-date information such as eruption chronology and geophysical monitoring data of a specific volcano using the direct link system to major volcano databases on the system. Currently, the system provides 3 simple, powerful and notable deterministic modeling simulation codes of volcanic processes, such as Energy Cone, Titan2D and Tephra2. The system provides deterministic tools because probabilistic assessment tools are normally much more computationally demanding. By using the volcano hazard assessment system, the area that would be affected by volcanic eruptions in any location near the volcano can be estimated using numerical simulations. The system is being implemented using the ASTER Global DEM covering 2790 Quaternary volcanoes in the world. The system can be used to evaluate volcanic hazards and move this toward risk-potential by overlaying the estimated distribution of volcanic gravity flows or tephra falls on major roads, houses and evacuation areas using the GIS-enabled systems. The system is developed for all users in the world who need volcanic hazards assessment tools.

Hazard analysis in uranium hexafluoride production facility

International Nuclear Information System (INIS)

Marin, Maristhela Passoni de Araujo

1999-01-01

The present work provides a method for preliminary hazard analysis of nuclear fuel cycle facilities. The proposed method identify both chemical and radiological hazards, as well as the consequences associated with accident scenarios. To illustrate the application of the method, a uranium hexafluoride production facility was selected. The main hazards are identified and the potential consequences are quantified. It was found that, although the facility handles radioactive material, the main hazards as associated with releases of toxic chemical substances such as hydrogen fluoride, anhydrous ammonia and nitric acid. It was shown that a contention bung can effectively reduce the consequences of atmospheric release of toxic materials. (author)

St. Louis area earthquake hazards mapping project; seismic and liquefaction hazard maps

Science.gov (United States)

Cramer, Chris H.; Bauer, Robert A.; Chung, Jae-won; Rogers, David; Pierce, Larry; Voigt, Vicki; Mitchell, Brad; Gaunt, David; Williams, Robert; Hoffman, David; Hempen, Gregory L.; Steckel, Phyllis; Boyd, Oliver; Watkins, Connor M.; Tucker, Kathleen; McCallister, Natasha

2016-01-01

We present probabilistic and deterministic seismic and liquefaction hazard maps for the densely populated St. Louis metropolitan area that account for the expected effects of surficial geology on earthquake ground shaking. Hazard calculations were based on a map grid of 0.005°, or about every 500 m, and are thus higher in resolution than any earlier studies. To estimate ground motions at the surface of the model (e.g., site amplification), we used a new detailed near‐surface shear‐wave velocity model in a 1D equivalent‐linear response analysis. When compared with the 2014 U.S. Geological Survey (USGS) National Seismic Hazard Model, which uses a uniform firm‐rock‐site condition, the new probabilistic seismic‐hazard estimates document much more variability. Hazard levels for upland sites (consisting of bedrock and weathered bedrock overlain by loess‐covered till and drift deposits), show up to twice the ground‐motion values for peak ground acceleration (PGA), and similar ground‐motion values for 1.0 s spectral acceleration (SA). Probabilistic ground‐motion levels for lowland alluvial floodplain sites (generally the 20–40‐m‐thick modern Mississippi and Missouri River floodplain deposits overlying bedrock) exhibit up to twice the ground‐motion levels for PGA, and up to three times the ground‐motion levels for 1.0 s SA. Liquefaction probability curves were developed from available standard penetration test data assuming typical lowland and upland water table levels. A simplified liquefaction hazard map was created from the 5%‐in‐50‐year probabilistic ground‐shaking model. The liquefaction hazard ranges from low (60% of area expected to liquefy) in the lowlands. Because many transportation routes, power and gas transmission lines, and population centers exist in or on the highly susceptible lowland alluvium, these areas in the St. Louis region are at significant potential risk from seismically induced liquefaction and associated

Biological productivity and potential resources of the exclusive economic zone (EEZ) of India

Digital Repository Service at National Institute of Oceanography (India)

Goswami, S.C.

An assessment of the biological production and the potential fishery resources has been made based on the data collected over a period of 15 years (1976-1991). The entire Exclusive Economic Zone (EEZ), measuring 2.02 million km sup(2) was divided...

Evaluation of the potential for bioaerosols from land applied biosolids

Energy Technology Data Exchange (ETDEWEB)

Tanner, Benjamin; Brooks, John; Josephseon, Karen; Gerba, Charles; Pepper, Ian

2003-07-01

The overall objective of this study was to quantitatively and qualitatively document the potential hazards of biological aerosols derived from land applied biosolids, and ultimately develop risk assessment models and land-management strategies for safe, effective use of biosolids. The specific objectives were: i) Quantify bacterial and viral microorganisms emitted as bioaerosols from point sources of biosolids, and area (land-applied) sources of biosolids; ii) Develop risk assessment models based on a) hazard identification, b) dose response, c) exposure assessment; d) risk characterization. Research has consisted of laboratory studies at the University of Arizona and field studies at several regional U.S. locations. Bioaerosol samples have been collected via ''Impingement'' using SKC biosamplers. The biologicals monitored for included: i) viruses: enteroviruses, calciviruses; ii) phage e.g, MS2; iii) E. coil; iv) Salmonella; v) total coliforms; vi) Clostridium perfringens; vii) Aspergillus spp.; viii) Endotoxin. Air samples were collected at discrete distances torn both biosolid piles (point sources), or land applied biosolids (area sources). (author)

Biological radiation effects

International Nuclear Information System (INIS)

Koggl, D.; Dedenkov, A.N.

1986-01-01

All nowadays problems of radio biology are considered: types of ionizing radiations, their interaction with material; damage of molecular structures and their reparation; reaction of cells and their recovery from radiation damage; reaction of the whole organism and its separate systems. Particular attention is given to the problems of radiation carcinogenesis and radiation hazard for man

Hydrotreater/Distillation Column Hazard Analysis Report Rev. 2

Energy Technology Data Exchange (ETDEWEB)

Lowry, Peter P. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Wagner, Katie A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

2016-04-15

This project Hazard and Risk Analysis Report contains the results of several hazard analyses and risk assessments. An initial assessment was conducted in 2012, which included a multi-step approach ranging from design reviews to a formal What-If hazard analysis. A second What-If hazard analysis was completed during February 2013 to evaluate the operation of the hydrotreater/distillation column processes to be installed in a process enclosure within the Process Development Laboratory West (PDL-West) facility located on the PNNL campus. The qualitative analysis included participation of project and operations personnel and applicable subject matter experts. The analysis identified potential hazardous scenarios, each based on an initiating event coupled with a postulated upset condition. The unmitigated consequences of each hazardous scenario were generally characterized as a process upset; the exposure of personnel to steam, vapors or hazardous material; a spray or spill of hazardous material; the creation of a flammable atmosphere; or an energetic release from a pressure boundary.

Relative hazard potential: the basis for definition of safety criteria for fast reactors

International Nuclear Information System (INIS)

Cave, L.; Ilberg, D.

1977-02-01

One of the main safety criteria to be met for larger thermal reactors is that the probability of exceeding the dose limits imposed by 10 CRF 100 should not be greater than 10 per reactor year. The potential hazard presented by a fast reactor could be substantially greater than that due to an LWR. The potential for harm of a reactor system may be judged by the effects which would arise from a severe accident. Several different types of effects may be considered: number of latent fatal cancers; number of deaths due to acute effects; number of thyroid tumors or nodules; extent of property damage; and genetic effects. Analytical methods for comparison are employed in this paper. A second important parameter reviewed in this report is the radio-toxicity attributed to the various isotopes. It was found that the worst conceivable accident to a 1000 MW(e) fast reactor would lead to effects on health greater by an order of magnitude than the worst accident usually considered for an LWR. Therefore, some reconsideration of the need for additional safety criteria for LMFBRs, as a guide to designers in relation to the control of the effects of very severe accidents, is desirable

Hazardous Substances Data Bank (HSDB)

Data.gov (United States)

U.S. Department of Health & Human Services — Comprehensive, peer-reviewed toxicology data for about 5,000 chemicals. The data bank focuses on the toxicology of potentially hazardous chemicals. It is enhanced...

Technological hazards in the understanding of society

International Nuclear Information System (INIS)

Diepold, W.

1977-01-01

This is a discussion of how employees of industry, an important part of society, and how the consumers and hence the whole volume of society express their attitude with respect to technological hazards in their practical activities and how the conclusions can be drawn from this that the population is thoroughly familiar in dealing with potential hazards. (orig.) [de

Fire Hazards Analysis for the 200 Area Interim Storage Area

International Nuclear Information System (INIS)

JOHNSON, D.M.

2000-01-01

This documents the Fire Hazards Analysis (FHA) for the 200 Area Interim Storage Area. The Interim Storage Cask, Rad-Vault, and NAC-1 Cask are analyzed for fire hazards and the 200 Area Interim Storage Area is assessed according to HNF-PRO-350 and the objectives of DOE Order 5480 7A. This FHA addresses the potential fire hazards associated with the Interim Storage Area (ISA) facility in accordance with the requirements of DOE Order 5480 7A. It is intended to assess the risk from fire to ensure there are no undue fire hazards to site personnel and the public and to ensure property damage potential from fire is within acceptable limits. This FHA will be in the form of a graded approach commensurate with the complexity of the structure or area and the associated fire hazards

Increasing resiliency to natural hazards - A strategic plan for the Multi-Hazards Demonstration Project in Southern California

Science.gov (United States)

Jones, Lucy; Bernknopf, Richard; Cannon, Susan; Cox, Dale A.; Gaydos, Len; Keeley, Jon; Kohler, Monica; Lee, Homa; Ponti, Daniel; Ross, Stephanie L.; Schwarzbach, Steven; Shulters, Michael; Ward, A. Wesley; Wein, Anne

2007-01-01

The U.S. Geological Survey (USGS) is initiating a new project designed to improve resiliency to natural hazards in southern California through the application of science to community decision making and emergency response. The Multi-Hazards Demonstration Project will assist the region’s communities to reduce their risk from natural hazards by directing new and existing research towards the community’s needs, improving monitoring technology, producing innovative products, and improving dissemination of the results. The natural hazards to be investigated in this project include coastal erosion, earthquakes, floods, landslides, tsunamis, and wildfires.Americans are more at risk from natural hazards now than at any other time in our Nation’s history. Southern California, in particular, has one of the Nation’s highest potentials for extreme catastrophic losses due to natural hazards, with estimates of expected losses exceeding $3 billion per year. These losses can only be reduced through the decisions of the southern California community itself. To be effective, these decisions must be guided by the best information about hazards, risk, and the cost-effectiveness of mitigation technologies. The USGS will work with collaborators to set the direction of the research and to create multi-hazard risk frameworks where communities can apply the results of scientific research to their decision-making processes. Partners include state, county, city, and public-lands government agencies, public and private utilities, companies with a significant impact and presence in southern California, academic researchers, the Federal Emergency Management Agency (FEMA), National Oceanic and Atmospheric Administration (NOAA), and local emergency response agencies.Prior to the writing of this strategic plan document, three strategic planning workshops were held in February and March 2006 at the USGS office in Pasadena to explore potential relationships. The goal of these planning

Hazard Classification and Auditable Safety Analysis for the 1300-N Emergency Dump Basin

International Nuclear Information System (INIS)

Kloster, G.L.

1998-01-01

This document combines three analytical functions consisting of (1) the hazards baseline of the Emergency Dump Basin (EDB) for surveillance and maintenance, (2) the final hazard classification for the facility, and (3) and auditable safety analysis. This document also describes the potential hazards contained within the EDB at the N Reactor complex and the vulnerabilities of those hazards. The EDB segment is defined and confirmed its independence from other segments at the site by demonstrating that no potential adverse interactions exist between the segments. No EDB hazards vulnerabilities were identified that require reliance on either active, mitigative, or protective measures; adequate facility structural integrity exists to safely control the hazards

A study of risk evaluation methodology selection for the external hazards

International Nuclear Information System (INIS)

Kuramoto, Takahiro; Yamaguchi, Akira; Narumiya, Yosiyuki

2014-01-01

Since the accident at Fukushima Daiichi Nuclear Power Plant caused by the Great East Japan Earthquake in March 2011, there has been growing demands for assessing the effects of external hazards, including natural events, such as earthquake and tsunami, and external human behaviors, and taking actions to address those external hazards. The newly established Japanese regulatory requirements claim design considerations associated with external hazards. The primary objective of the risk assessment for external hazards is to establish countermeasures against such hazards rather than grasping the risk figures. Therefore, applying detailed risk assessment methods, such as probabilistic risk assessment (PRA), to all the external hazards is not always the most appropriate. Risk assessment methods can vary in types including qualitative evaluation, hazard analysis (analyzing hazard frequencies or their influence), and margin assessment. To resolve these issues, a process has been established that enables us to identify the external hazards in a comprehensive and systematic manner, which have potential risks leading to core damage and to select an appropriate evaluation method according to the risks associated with each of the external hazards. This paper discusses the comprehensive and systematic identification process for the external hazards which have potential risks leading to core damage, and the approaches of selecting an appropriate evaluation method for each external hazard. This paper also describes some applications of specific risk evaluation methods. (author)

Health hazards and disaster potential of ground gas emissions at Furnas volcano, São Miguel, Azores

Science.gov (United States)

Baxter, Peter J.; Baubron, Jean-Claude; Coutinho, Rui

1999-09-01

A health hazard assessment of exposure to soil gases (carbon dioxide and radon) was undertaken in the village of Furnas, located in the caldera of an active volcano. A soil survey to map the area of soil gas flow was undertaken, gas emissions were monitored at fumaroles and in eight houses, and a preliminary radon survey of 23 houses in the main anomaly area was performed. Potential volcanic sources of toxic contamination of air, food, and water were also investigated, and ambient air quality was evaluated. About one-third (41 ha) of the houses were located in areas of elevated carbon dioxide soil degassing. Unventilated, confined spaces in some houses contained levels of carbon dioxide which could cause asphyxiation. Mean indoor radon levels exceeded UK and US action levels in the winter months. A tenfold increase in radon levels in one house over 2 h indicated that large and potentially lethal surges of carbon dioxide could occur without warning. Toxic exposures from the gaseous emissions and from contamination of soil and water were minimal, but sulphur dioxide levels were mildly elevated close to fumaroles. In contrast, evidence of dental fluorosis was manifested in the population of the nearby fishing village of Ribeira Quente where drinking water in the past had contained elevated levels of fluoride. The disaster potential of volcanic carbon dioxide in the area could also be associated with the hydrothermal system storing dissolved carbon dioxide beneath the village. Felt, or unfelt, seismic activity, or magma unrest, especially with a reawakening of explosive volcanic activity (30% probability in the next 100 years) could result in an increase in gas flow or even a gas burst from the hydrothermal system. A survey of all houses in Furnas is advised as structural measures to prevent the ingress of soil gases, including radon, were needed in some of the study houses. Evaluations of the human hazards of volcanic gases should be undertaken in all settlements in

Modified Hazard Ranking System/Hazard Ranking System for sites with mixed radioactive and hazardous wastes: Software documentation

Energy Technology Data Exchange (ETDEWEB)

Stenner, R.D.; Peloquin, R.A.; Hawley, K.A.

1986-11-01

The mHRS/HRS software package was developed by the Pacific Northwest Laboratory (PNL) under contract with the Department of Energy (DOE) to provide a uniform method for DOE facilities to use in performing their Conservation Environmental Response Compensation and Liability Act (CERCLA) Phase I Modified Hazard Ranking System or Hazard Ranking System evaluations. The program is designed to remove the tedium and potential for error associated with the performing of hand calculations and the interpreting of information on tables and in reference books when performing an evaluation. The software package is designed to operate on a microcomputer (IBM PC, PC/XT, or PC/AT, or a compatible system) using either a dual floppy disk drive or a hard disk storage system. It is written in the dBASE III language and operates using the dBASE III system. Although the mHRS/HRS software package was developed for use at DOE facilities, it has direct applicability to the performing of CERCLA Phase I evaluations for any facility contaminated by hazardous waste. The software can perform evaluations using either the modified hazard ranking system methodology developed by DOE/PNL, the hazard ranking system methodology developed by EPA/MITRE Corp., or a combination of the two. This document is a companion manual to the mHRS/HRS user manual. It is intended for the programmer who must maintain the software package and for those interested in the computer implementation. This manual documents the system logic, computer programs, and data files that comprise the package. Hardware and software implementation requirements are discussed. In addition, hand calculations of three sample situations (problems) with associated computer runs used for the verification of program calculations are included.

Modified Hazard Ranking System/Hazard Ranking System for sites with mixed radioactive and hazardous wastes: Software documentation

International Nuclear Information System (INIS)

Stenner, R.D.; Peloquin, R.A.; Hawley, K.A.

1986-11-01

The mHRS/HRS software package was developed by the Pacific Northwest Laboratory (PNL) under contract with the Department of Energy (DOE) to provide a uniform method for DOE facilities to use in performing their Conservation Environmental Response Compensation and Liability Act (CERCLA) Phase I Modified Hazard Ranking System or Hazard Ranking System evaluations. The program is designed to remove the tedium and potential for error associated with the performing of hand calculations and the interpreting of information on tables and in reference books when performing an evaluation. The software package is designed to operate on a microcomputer (IBM PC, PC/XT, or PC/AT, or a compatible system) using either a dual floppy disk drive or a hard disk storage system. It is written in the dBASE III language and operates using the dBASE III system. Although the mHRS/HRS software package was developed for use at DOE facilities, it has direct applicability to the performing of CERCLA Phase I evaluations for any facility contaminated by hazardous waste. The software can perform evaluations using either the modified hazard ranking system methodology developed by DOE/PNL, the hazard ranking system methodology developed by EPA/MITRE Corp., or a combination of the two. This document is a companion manual to the mHRS/HRS user manual. It is intended for the programmer who must maintain the software package and for those interested in the computer implementation. This manual documents the system logic, computer programs, and data files that comprise the package. Hardware and software implementation requirements are discussed. In addition, hand calculations of three sample situations (problems) with associated computer runs used for the verification of program calculations are included

HAZARDOUS WASTE DECONTAMINATION WITH PLASMA REACTORS

Science.gov (United States)

The use of electrical energy in the form of plasma has been considered as a potentially efficient means of decontaminating hazardous waste, although to date only a few attempts have been made to do so. There are a number of relative advantages and some potential disadvantages to...

Impacts on health and safety from transfer/consolidation of nuclear materials and hazardous chemicals

International Nuclear Information System (INIS)

Gallucci, R.H.V.

1994-11-01

Environmental restoration plans at the US Department of Energy (USDOE) Hanford Site calls for transfer/consolidation of ''targets/threats,'' namely nuclear materials and hazardous chemicals. Reductions in the health and safety hazards will depend on the plans implemented. Pacific Northwest Laboratory (PNL) estimated these potential impacts, assuming implementation of the current reference plan and employing ongoing risk and safety analyses. The results indicated the potential for ''significant'' reductions in health and safety hazards in the long term (> 25 years) and a potentially ''noteworthy'' reduction in health hazard in the short term (≤ 25 years)

Application of a non-hazardous vital dye for cell counting with automated cell counters.

Science.gov (United States)

Kim, Soo In; Kim, Hyun Jeong; Lee, Ho-Jae; Lee, Kiwon; Hong, Dongpyo; Lim, Hyunchang; Cho, Keunchang; Jung, Neoncheol; Yi, Yong Weon

2016-01-01

Recent advances in automated cell counters enable us to count cells more easily with consistency. However, the wide use of the traditional vital dye trypan blue (TB) raises environmental and health concerns due to its potential teratogenic effects. To avoid this chemical hazard, it is of importance to introduce an alternative non-hazardous vital dye that is compatible with automated cell counters. Erythrosin B (EB) is a vital dye that is impermeable to biological membranes and is used as a food additive. Similarly to TB, EB stains only nonviable cells with disintegrated membranes. However, EB is less popular than TB and is seldom used with automated cell counters. We found that cell counting accuracy with EB was comparable to that with TB. EB was found to be an effective dye for accurate counting of cells with different viabilities across three different automated cell counters. In contrast to TB, EB was less toxic to cultured HL-60 cells during the cell counting process. These results indicate that replacing TB with EB for use with automated cell counters will significantly reduce the hazardous risk while producing comparable results. Copyright © 2015 Logos Biosystems, Inc. Published by Elsevier Inc. All rights reserved.

Preliminary hazards analysis -- vitrification process

International Nuclear Information System (INIS)

Coordes, D.; Ruggieri, M.; Russell, J.; TenBrook, W.; Yimbo, P.

1994-06-01

This paper presents a Preliminary Hazards Analysis (PHA) for mixed waste vitrification by joule heating. The purpose of performing a PHA is to establish an initial hazard categorization for a DOE nuclear facility and to identify those processes and structures which may have an impact on or be important to safety. The PHA is typically performed during and provides input to project conceptual design. The PHA is then followed by a Preliminary Safety Analysis Report (PSAR) performed during Title 1 and 2 design. The PSAR then leads to performance of the Final Safety Analysis Report performed during the facility's construction and testing. It should be completed before routine operation of the facility commences. This PHA addresses the first four chapters of the safety analysis process, in accordance with the requirements of DOE Safety Guidelines in SG 830.110. The hazards associated with vitrification processes are evaluated using standard safety analysis methods which include: identification of credible potential hazardous energy sources; identification of preventative features of the facility or system; identification of mitigative features; and analyses of credible hazards. Maximal facility inventories of radioactive and hazardous materials are postulated to evaluate worst case accident consequences. These inventories were based on DOE-STD-1027-92 guidance and the surrogate waste streams defined by Mayberry, et al. Radiological assessments indicate that a facility, depending on the radioactive material inventory, may be an exempt, Category 3, or Category 2 facility. The calculated impacts would result in no significant impact to offsite personnel or the environment. Hazardous materials assessment indicates that a Mixed Waste Vitrification facility will be a Low Hazard facility having minimal impacts to offsite personnel and the environment

Preliminary hazards analysis -- vitrification process

Energy Technology Data Exchange (ETDEWEB)

Coordes, D.; Ruggieri, M.; Russell, J.; TenBrook, W.; Yimbo, P. [Science Applications International Corp., Pleasanton, CA (United States)

1994-06-01

This paper presents a Preliminary Hazards Analysis (PHA) for mixed waste vitrification by joule heating. The purpose of performing a PHA is to establish an initial hazard categorization for a DOE nuclear facility and to identify those processes and structures which may have an impact on or be important to safety. The PHA is typically performed during and provides input to project conceptual design. The PHA is then followed by a Preliminary Safety Analysis Report (PSAR) performed during Title 1 and 2 design. The PSAR then leads to performance of the Final Safety Analysis Report performed during the facility`s construction and testing. It should be completed before routine operation of the facility commences. This PHA addresses the first four chapters of the safety analysis process, in accordance with the requirements of DOE Safety Guidelines in SG 830.110. The hazards associated with vitrification processes are evaluated using standard safety analysis methods which include: identification of credible potential hazardous energy sources; identification of preventative features of the facility or system; identification of mitigative features; and analyses of credible hazards. Maximal facility inventories of radioactive and hazardous materials are postulated to evaluate worst case accident consequences. These inventories were based on DOE-STD-1027-92 guidance and the surrogate waste streams defined by Mayberry, et al. Radiological assessments indicate that a facility, depending on the radioactive material inventory, may be an exempt, Category 3, or Category 2 facility. The calculated impacts would result in no significant impact to offsite personnel or the environment. Hazardous materials assessment indicates that a Mixed Waste Vitrification facility will be a Low Hazard facility having minimal impacts to offsite personnel and the environment.

The clearance potential index and hazard factors of CANDU fuel bundle and a comparison of experimental-calculated inventories

International Nuclear Information System (INIS)

Pavelescu, Alexandru Octavian; Cepraga, Dan Gabriel

2007-01-01

In the field of radioactive waste management, the radiotoxicity can be characterized by two different approaches: 1) IAEA, 2004 RS-G-1.7 clearance concept and 2) US, 10CFR20 radioactivity concentration guides in terms of ingestion / inhalation hazard expressed in m 3 of water/air. A comparison between the two existing safety concepts was made in the paper. The modeled case was a CANDU natural uranium, 37 elements fuel bundle with a reference burnup of 685 GJ/kgU (7928.24 MWd/tU). The radiotoxicity of the light nuclide inventories, actinide, and fission-products was calculated in the paper. The calculation was made using the ORIGEN-S from ORIGEN4.4a in conjunction with the activation-burnup library and an updated decay data library with clearance levels data in ORIGEN format produced by WIMS-AECL/SCALENEA-1 code system. Both the radioactivity concentration expressed in Curie and Becquerel, and the clearance index and ingestion / inhalation hazard were calculated for the radionuclides contained in 1 kg of irradiated fuel element at shutdown and for 1, 50, 1500 years cooling time. This study required a complex activity that consisted of various phases such us: the acquisition, setting up, validation and application of procedures, codes and libraries. For the validation phase of the study, the objective was to compare the measured inventories of selected actinide and fission products radionuclides in an element from a Pickering CANDU reactor with inventories predicted using a recent version of the ORIGEN-ARP from SCALE 5 coupled with the time dependent cross sections library, CANDU 28.lib, produced by the sequence SAS2H of SCALE 4.4a. In this way, the procedures, codes and libraries for the characterization of radioactive material in terms of radioactive inventories, clearance, and biological hazard factors are being qualified and validated, in support for the safety management of the radioactive wastes

A proposal for performing software safety hazard analysis

International Nuclear Information System (INIS)

Lawrence, J.D.; Gallagher, J.M.

1997-01-01

Techniques for analyzing the safety and reliability of analog-based electronic protection systems that serve to mitigate hazards in process control systems have been developed over many years, and are reasonably understood. An example is the protection system in a nuclear power plant. The extension of these techniques to systems which include digital computers is not well developed, and there is little consensus among software engineering experts and safety experts on how to analyze such systems. One possible technique is to extend hazard analysis to include digital computer-based systems. Software is frequently overlooked during system hazard analyses, but this is unacceptable when the software is in control of a potentially hazardous operation. In such cases, hazard analysis should be extended to fully cover the software. A method for performing software hazard analysis is proposed in this paper. The method concentrates on finding hazards during the early stages of the software life cycle, using an extension of HAZOP

Supplemental Hazard Analysis and Risk Assessment - Hydrotreater

Energy Technology Data Exchange (ETDEWEB)

Lowry, Peter P. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Wagner, Katie A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

2015-04-01

A supplemental hazard analysis was conducted and quantitative risk assessment performed in response to an independent review comment received by the Pacific Northwest National Laboratory (PNNL) from the U.S. Department of Energy Pacific Northwest Field Office (PNSO) against the Hydrotreater/Distillation Column Hazard Analysis Report issued in April 2013. The supplemental analysis used the hazardous conditions documented by the previous April 2013 report as a basis. The conditions were screened and grouped for the purpose of identifying whether additional prudent, practical hazard controls could be identified, using a quantitative risk evaluation to assess the adequacy of the controls and establish a lower level of concern for the likelihood of potential serious accidents. Calculations were performed to support conclusions where necessary.

Exploratory Studies Facility Subsurface Fire Hazards Analysis

International Nuclear Information System (INIS)

Logan, Richard C.

2002-01-01

The primary objective of this Fire Hazard Analysis (FHA) is to confirm the requirements for a comprehensive fire and related hazards protection program for the Exploratory Studies Facility (ESF) are sufficient to minimize the potential for: The occurrence of a fire or related event; A fire that causes an unacceptable on-site or off-site release of hazardous or radiological material that will threaten the health and safety of employees, the public or the environment; Vital U.S. Department of Energy (DOE) programs suffering unacceptable interruptions as a result of fire and related hazards; Property losses from a fire and related events exceeding limits established by DOE; and Critical process controls and safety class systems being damaged as a result of a fire and related events

Probabilistic tsunami hazard assessment for Point Lepreau Generating Station

Energy Technology Data Exchange (ETDEWEB)

Mullin, D., E-mail: dmullin@nbpower.com [New Brunswick Power Corporation, Point Lepreau Generating Station, Point Lepreau (Canada); Alcinov, T.; Roussel, P.; Lavine, A.; Arcos, M.E.M.; Hanson, K.; Youngs, R., E-mail: trajce.alcinov@amecfw.com, E-mail: patrick.roussel@amecfw.com [AMEC Foster Wheeler Environment & Infrastructure, Dartmouth, NS (Canada)

2015-07-01

In 2012 the Geological Survey of Canada published a preliminary probabilistic tsunami hazard assessment in Open File 7201 that presents the most up-to-date information on all potential tsunami sources in a probabilistic framework on a national level, thus providing the underlying basis for conducting site-specific tsunami hazard assessments. However, the assessment identified a poorly constrained hazard for the Atlantic Coastline and recommended further evaluation. As a result, NB Power has embarked on performing a Probabilistic Tsunami Hazard Assessment (PTHA) for Point Lepreau Generating Station. This paper provides the methodology and progress or hazard evaluation results for Point Lepreau G.S. (author)

Volcanic Hazards in Site Evaluation for Nuclear Installations

Energy Technology Data Exchange (ETDEWEB)

NONE

2012-10-15

This publication provides comprehensive and updated guidance for site evaluation in relation to volcanic hazards. It includes recommendations on assessing the volcanic hazards at a nuclear installation site, in order to identify and characterize, in a comprehensive manner, all potentially hazardous phenomena that may be associated with future volcanic events. It describes how some of these volcanic phenomena may affect the acceptability of the selected site, resulting in exclusion of a site or determining the corresponding design basis parameters for the installation. This Safety Guide is applicable to both existing and new sites, and a graded approach is recommended to cater for all types of nuclear installations. Contents: 1. Introduction; 2. Overview of volcanic hazard assessment; 3. General recommendations; 4. Necessary information and investigations (database); 5. Screening of volcanic hazards; 6. Site specific volcanic hazard assessment; 7. Nuclear installations other than nuclear power plants; 8. Monitoring and preparation for response; 9. Management system for volcanic hazard assessment; Annex I: Volcanic hazard scenarios; Annex II: Worldwide sources of information.

Evaluation and control of radon daughter hazards in uranium mines

International Nuclear Information System (INIS)

Holaday, D.A.

1974-11-01

This monograph discusses primarily those health hazards to uranium miners which are produced by exposure to ionizing radiation. Emphasis is placed on the areas of evaluation of exposures to the radioactive gas radon-222 and its short-lived transformation products, and methods of controlling such exposures. A limited discussion of the biological effects of radon and radon daughters is undertaken, and some procedures are given for evaluating hazards created by other common contaminants of mine atmospheres. A large amount of information exists on these topics, some of which is unpublished or is not readily available. While efforts were made to obtain data from all sources, undoubtedly some valuable work was overlooked. The monograph is an endeavor to assemble pertinent information and make it available to those who are concerned with producing uranium at minimal risks. Where they were available, a variety of procedures for evaluating hazards are given, and examples of systems for controlling hazards are included. 154 references

Wind hazard assessment for Point Lepreau Generating Station

International Nuclear Information System (INIS)

Mullin, D.; Moland, M.; Sciaudone, J.C.; Twisdale, L.A.; Vickery, P.J.; Mizzen, D.R.

2015-01-01

In response to the CNSC Fukushima Action Plan, NB Power has embarked on a wind hazard assessment for the Point Lepreau Generating Station site that incorporates the latest up to date wind information and modeling. The objective was to provide characterization of the wind hazard from all potential sources and estimate wind-driven missile fragilities and wind pressure fragilities for various structures, systems and components that would provide input to a possible high wind Probabilistic Safety Assessment. The paper will discuss the overall methodology used to assess hazards related to tornadoes, hurricanes and straight-line winds, and site walk-down and hazard/fragility results. (author)

Biological risks associated with consumption of reptile products

DEFF Research Database (Denmark)

Magnino, S.; Colin, P.; Dei-Cas, E.

2009-01-01

recently increased in some areas of the world. Biological risks associated with the consumption of products from both farmed and wild reptile meat and eggs include infections caused by bacteria (Salmonella spp., Vibrio spp.). parasites (Spirometra, Trichinella, Gnathostoma, pentastomids), as well...... to increase the occurrence of biological hazards in reptile meat. Application of GHP, GMP and HACCP procedures, respectively at farm and slaughterhouse level, is crucial for controlling the hazards.......The consumption of a wide variety of species of reptiles caught from the wild has been an important source of protein for humans world-wide for millennia. Terrapins. snakes, lizards, crocodiles and iguanas are now farmed and the consumption and trade of their meat and other edible products have...

283-E and 283-W hazards assessment

International Nuclear Information System (INIS)

Sutton, L.N.

1994-01-01

This report documents the hazards assessment for the 200 area water treatment plants 283-E and 283-W located on the US DOE Hanford Site. Operation of the water treatment plants is the responsibility of ICF Kaiser Hanford Company (ICF KH). This hazards assessment was conducted to provide emergency planning technical basis for the water treatment plants. This document represents an acceptable interpretation of the implementing guidance document for DOE ORDER 5500.3A which requires an emergency planning hazards assessment for each facility that has the potential to reach or exceed the lowest level emergency classification

Parasites of wild animals as a potential source of hazard to humans.

Science.gov (United States)

Gałęcki, Remigiusz; Sokół, Rajmund; Koziatek, Sylwia

2015-01-01

The decline in wild animal habitats and the uncontrolled growth of their population make these animals come closer to human settlements. The aim of the study was to identify parasitic infections in wild animals in the selected area, and to specify the hazards they create for humans. In more than 66% of the analysed faecal samples from wild boar, hares, roe deer, deer and fallow deer various developmental forms of parasites were found. These included parasites dangerous for humans: Toxocara canis, Capillaria hepatica, Capillaria bovis, Trichuris suis, Trichuris ovis, Trichuris globulosus, Eimeria spp., and Trichostongylus spp. It is necessary to monitor parasitic diseases in wild animals as they can lead to the spread of parasites creating a hazard to humans, pets and livestock.

Hazards assessment for the INEL Landfill Complex

International Nuclear Information System (INIS)

Knudsen, J.K.; Calley, M.B.

1994-02-01

This report documents the hazards assessment for the INEL Landfill Complex (LC) located at the Idaho National Engineering Laboratory, which is operated by EG ampersand G Idaho, Inc., for the US Department of Energy (DOE). The hazards assessment was performed to ensure that this facility complies with DOE and company requirements pertaining to emergency planning and preparedness for operational emergencies. DOE Order 5500.3A requires that a facility-specific hazards assessment be performed to provide the technical basis for facility emergency planning efforts. This hazards assessment was conducted in accordance with DOE Headquarters and the DOE Idaho Operations Office (DOE-ID) guidance to comply with DOE Order 5500.3A. The hazards assessment identifies and analyzes the hazards that are significant enough to warrant consideration in a facility's operational emergency management program. The area surrounding the LC, the buildings and structures at the LC, and the processes that are used at the LC are described in this report. All hazardous materials, both radiological and nonradiological, at the LC were identified and screened against threshold quantities according to DOE Order 5500.3A guidance. Asbestos at the Asbestos Pit was the only hazardous material that exceeded its specified threshold quantity. However, the type of asbestos received and the packaging practices used are believed to limit the potential for an airborne release of asbestos fibers. Therefore, in accordance with DOE Order 5500.3A guidance, no further hazardous material characterization or analysis was required for this hazards assessment

Hazards assessment for the INEL Landfill Complex

Energy Technology Data Exchange (ETDEWEB)

Knudsen, J.K.; Calley, M.B.

1994-02-01

This report documents the hazards assessment for the INEL Landfill Complex (LC) located at the Idaho National Engineering Laboratory, which is operated by EG&G Idaho, Inc., for the US Department of Energy (DOE). The hazards assessment was performed to ensure that this facility complies with DOE and company requirements pertaining to emergency planning and preparedness for operational emergencies. DOE Order 5500.3A requires that a facility-specific hazards assessment be performed to provide the technical basis for facility emergency planning efforts. This hazards assessment was conducted in accordance with DOE Headquarters and the DOE Idaho Operations Office (DOE-ID) guidance to comply with DOE Order 5500.3A. The hazards assessment identifies and analyzes the hazards that are significant enough to warrant consideration in a facility`s operational emergency management program. The area surrounding the LC, the buildings and structures at the LC, and the processes that are used at the LC are described in this report. All hazardous materials, both radiological and nonradiological, at the LC were identified and screened against threshold quantities according to DOE Order 5500.3A guidance. Asbestos at the Asbestos Pit was the only hazardous material that exceeded its specified threshold quantity. However, the type of asbestos received and the packaging practices used are believed to limit the potential for an airborne release of asbestos fibers. Therefore, in accordance with DOE Order 5500.3A guidance, no further hazardous material characterization or analysis was required for this hazards assessment.

Survey of potential health and safety hazards of commercial-scale ethanol production facilities

Energy Technology Data Exchange (ETDEWEB)

Watson, A.P.; Smith, J.G.; Elmore, J.L.

1982-04-01

Generic safety and health aspects of commercial-scale (60 to 600 million L/y) anhydrous ethanol production were identified. Several common feedstocks (grains, roots and fibers, and sugarcane) and fuels (coal, natural gas, wood, and bagasse) were evaluated throughout each step of generic plant operation, from initial milling and sizing through saccharification, fermentation, distillation, and stillage disposal. The fermentation, digestion, or combustion phases are not particularly hazardous, although the strong acids and bases used for hydrolysis and pH adjustment should be handled with the same precautions that every industrial solvent deserves. The most serious safety hazard is that of explosion from grain dust or ethanol fume ignition and boiler/steam line overpressurization. Inhalation of ethanol and carbon dioxide vapors may cause intoxication or asphyxiation in unventilated areas, which could be particularly hazardous near equipment controls and agitating vats. Contact with low-pressure process steam would produce scalding burns. Benzene, used in stripping water from ethanol in the final distillation column, is a suspected leukemogen. Substitution of this fluid by alternative liquids is addressed.

Neutrino radiation hazards: A paper tiger

International Nuclear Information System (INIS)

Cossairt, J.D.; Grossman, N.L.; Marshall, E.T.

1996-09-01

Neutrinos are present in the natural environment due to terrestrial, solar, and cosmic sources and are also produced at accelerators both incidentally and intentionally as part of physics research programs. Progress in fundamental physics research has led to the creation of beams of neutrinos of ever-increasing intensity and/or energy. The large size and cost associated with these beams attracts, and indeed requires, public interest, support, and some understanding of the 'exotic' particles produced, including the neutrinos. Furthermore, the very word neutrino ('little neutral one', as coined by Enrico Fermi) can lead to public concern due to confusion with 'neutron', a word widely associated with radiological hazards. Adding to such possible concerns is a recent assertion, widely publicized, that neutrinos from astronomical events may have led to the extinction of some biological species. Presented here are methods for conservatively estimating the dose equivalent due to neutrinos as well as an assessment of the possible role of neutrinos in biological extinction processes. It is found that neutrinos produced by the sun and modern particle accelerators produce inconsequential dose equivalent rates. Examining recent calculations concerning neutrinos incident upon the earth due to stellar collapse, it is concluded that it is highly unlikely that these neutrinos caused the mass extinctions of species found in the paleontological record. Neutrino radiation hazards are, then, truly a 'paper tiger'. 14 refs., 1 fig., 1 tab

An OSHA based approach to safety analysis for nonradiological hazardous materials

International Nuclear Information System (INIS)

Yurconic, M.

1992-08-01

The PNL method for chemical hazard classification defines major hazards by means of a list of hazardous substances (or chemical groups) with associated trigger quantities. In addition, the functional characteristics of the facility being classified is also be factored into the classification. In this way, installations defined as major hazard will only be those which have the potential for causing very serious incidents both on and off site. Because of the diversity of operations involving chemicals, it may not be possible to restrict major hazard facilities to certain types of operations. However, this hazard classification method recognizes that in the industrial sector major hazards are most commonly associated with activities involving very large quantities of chemicals and inherently energetic processes. These include operations like petrochemical plants, chemical production, LPG storage, explosives manufacturing, and facilities which use chlorine, ammonia, or other highly toxic gases in bulk quantities. The basis for this methodology is derived from concepts used by OSHA in its proposed chemical process safety standard, the Dow Fire and Explosion Index Hazard Classification Guide, and the International Labor Office's program on chemical safety. For the purpose of identifying major hazard facilities, this method uses two sorting criteria, (1) facility function and processes and (2) quantity of substances to identify facilities requiringclassification. Then, a measure of chemical energy potential (material factor) is used to identify high hazard class facilities

Navy Shipboard Hazardous Material Minimization Program

Energy Technology Data Exchange (ETDEWEB)

Bieberich, M.J. [Naval Surface Warfare Center, Annapolis, MD (United States). Carderock Div.; Robinson, P. [Life Cycle Engineering, Inc., Charleston, SC (United States); Chastain, B.

1994-12-31

The use of hazardous (and potentially hazardous) materials in shipboard cleaning applications has proliferated as new systems and equipments have entered the fleet to reside alongside existing equipments. With the growing environmental awareness (and additional, more restrictive regulations) at all levels/echelon commands of the DoD, the Navy has initiated a proactive program to undertake the minimization/elimination of these hazardous materials in order to eliminate HMs at the source. This paper will focus on the current Shipboard Hazardous Materials Minimization Program initiatives including the identification of authorized HM currently used onboard, identification of potential substitute materials for HM replacement, identification of new cleaning technologies and processes/procedures, and identification of technical documents which will require revision to eliminate the procurement of HMs into the federal supply system. Also discussed will be the anticipated path required to implement the changes into the fleet and automated decision processes (substitution algorithm) currently employed. The paper will also present the most recent technologies identified for approval or additional testing and analysis including: supercritical CO{sub 2} cleaning, high pressure blasting (H{sub 2}O + baking soda), aqueous and semi-aqueous cleaning materials and processes, solvent replacements and dedicated parts washing systems with internal filtering capabilities, automated software for solvent/cleaning process substitute selection. Along with these technological advances, data availability (from on-line databases and CDROM Database libraries) will be identified and discussed.

Method for decreasing radiation hazard in transporting radioactive material

International Nuclear Information System (INIS)

Wodrich, D.D.

1975-01-01

At the end of their useful life, fuel rods are removed from a nuclear reactor and transferred underwater into a shipping cask. The water in the pool of the nuclear reactor system (or fuels reprocessing plant) may contain troublesome amounts of radioactive isotopes, creating biological hazards for any shipping cask unless adequately cleaned after contacting pool water. Potential contamination of substantially all of the entire exterior of the shipping cask is avoided because such shipping cask is at least predominantly immersed in fresh water within a vertically shiftable container which can be, for example, shifted between the bottom and the surface of the pool. Fresh water is supplied to the interior of the shiftable container whereby substantially all of the exterior of the shipping cask is immersed in fresh water, maintained at a pressure and/or flow velocity preventing the pool water from contacting the exterior of the shipping cask

Transportation of Hazardous Materials Emergency Preparedness Hazards Assessment

Energy Technology Data Exchange (ETDEWEB)

Blanchard, A.

2000-02-28

This report documents the Emergency Preparedness Hazards Assessment (EPHA) for the Transportation of Hazardous Materials (THM) at the Department of Energy (DOE) Savannah River Site (SRS). This hazards assessment is intended to identify and analyze those transportation hazards significant enough to warrant consideration in the SRS Emergency Management Program.

Transportation of Hazardous Materials Emergency Preparedness Hazards Assessment

International Nuclear Information System (INIS)

Blanchard, A.

2000-01-01

This report documents the Emergency Preparedness Hazards Assessment (EPHA) for the Transportation of Hazardous Materials (THM) at the Department of Energy (DOE) Savannah River Site (SRS). This hazards assessment is intended to identify and analyze those transportation hazards significant enough to warrant consideration in the SRS Emergency Management Program

Transportation of hazardous materials emergency preparedness hazards assessment

International Nuclear Information System (INIS)

Blanchard, A.

2000-01-01

This report documents the Emergency Preparedness Hazards Assessment (EPHA) for the Transportation of Hazardous Materials (THM) at the Department of Energy (DOE) Savannah River Site (SRS). This hazards assessment is intended to identify and analyze those transportation hazards significant enough to warrant consideration in the SRS Emergency Management Program

Biological effects of radiation human health and safety

International Nuclear Information System (INIS)

1977-05-01

The biological hazards of nuclear energy usage are a growing source of public concern. The medical profession may well be expected to contribute to public debate on the issue. This document, therefore, attempts a balanced review of the known and suspected human biological consequences of exposure to different types of ionizing radiation, emphasizing in particular the nuclear industry

Hazardous substances shipping at inland water harbors

International Nuclear Information System (INIS)

Benkovic, Z.

2009-01-01

Safety measures and regulations system covering the aspects of fire protection, professional and ecological safety are aimed to create a safe working environment, by detection and remedy of conditions that are potentially hazardous for the well-being of the employees or are leading to certain undesired events. Such unwanted incidents may result in different consequences: operating person's injury, environment pollution or material damage. This study attempts to illustrate the organization of work during hazardous matter loading and unloading at inland water harbors, based on legal provisions and decrees involving safety precautions, and in order to achieve constant enhancement of operating procedure, decreasing thereby the number of work-related injuries and various accidental situations. Fundamental precondition required to prevent possible accidents and to optimize general safety policy is to recognize and control any danger or potential hazard, as well as to be familiar with the legal provisions covering the inland waterway transport of harmful substances.(author)

Statistical analysis of the uncertainty related to flood hazard appraisal

Science.gov (United States)

Notaro, Vincenza; Freni, Gabriele

2015-12-01

The estimation of flood hazard frequency statistics for an urban catchment is of great interest in practice. It provides the evaluation of potential flood risk and related damage and supports decision making for flood risk management. Flood risk is usually defined as function of the probability, that a system deficiency can cause flooding (hazard), and the expected damage, due to the flooding magnitude (damage), taking into account both the exposure and the vulnerability of the goods at risk. The expected flood damage can be evaluated by an a priori estimation of potential damage caused by flooding or by interpolating real damage data. With regard to flood hazard appraisal several procedures propose to identify some hazard indicator (HI) such as flood depth or the combination of flood depth and velocity and to assess the flood hazard corresponding to the analyzed area comparing the HI variables with user-defined threshold values or curves (penalty curves or matrixes). However, flooding data are usually unavailable or piecemeal allowing for carrying out a reliable flood hazard analysis, therefore hazard analysis is often performed by means of mathematical simulations aimed at evaluating water levels and flow velocities over catchment surface. As results a great part of the uncertainties intrinsic to flood risk appraisal can be related to the hazard evaluation due to the uncertainty inherent to modeling results and to the subjectivity of the user defined hazard thresholds applied to link flood depth to a hazard level. In the present work, a statistical methodology was proposed for evaluating and reducing the uncertainties connected with hazard level estimation. The methodology has been applied to a real urban watershed as case study.

Modes of occurrence of potentially hazardous elements in coal: levels of confidence

Science.gov (United States)

Finkelman, R.B.

1994-01-01

The modes of occurrence of the potentially hazardous elements in coal will be of significance in any attempt to reduce their mobilization due to coal combustion. Antimony and selenium may be present in solid solution in pyrite, as minute accessory sulfides dispersed throughout the organic matrix, or in organic association. Because of these modes of occurrence it is anticipated that less than 50% of these elements will be routinely removed by conventional coal cleaning procedures. Arsenic and mercury occur primarily in late-stage coarse-grained pyrite therefore physical coal cleaning procedures should be successful in removing substantial proportions of these elements. Cadmium occurs in sphalerite and lead in galena. Both of these minerals exhibit a wide range of particle sizes and textural relations. Depending on the particle size and textural relations, physical coal cleaning may remove as little as 25% of these elements or as much as 75%. Manganese in bituminous coal occurs in carbonates, especially siderite. Physical coal cleaning should remove a substantial proportion of this element. More information is needed to elucidate the modes of occurrence of beryllium, chromium, cobalt, and nickel. ?? 1994.

Exploratory Studies Facility Subsurface Fire Hazards Analysis

International Nuclear Information System (INIS)

Kubicek, J. L.

2001-01-01

The primary objective of this Fire Hazard Analysis (FHA) is to confirm the requirements for a comprehensive fire and related hazards protection program for the Exploratory Studies Facility (ESF) are sufficient to minimize the potential for: (1) The occurrence of a fire or related event. (2) A fire that causes an unacceptable on-site or off-site release of hazardous or radiological material that will threaten the health and safety of employees, the public or the environment. (3) Vital US. Department of Energy (DOE) programs suffering unacceptable interruptions as a result of fire and related hazards. (4) Property losses from a fire and related events exceeding limits established by DOE. (5) Critical process controls and safety class systems being damaged as a result of a fire and related events

Hazard function theory for nonstationary natural hazards

Science.gov (United States)

Read, L.; Vogel, R. M.

2015-12-01

Studies from the natural hazards literature indicate that many natural processes, including wind speeds, landslides, wildfires, precipitation, streamflow and earthquakes, show evidence of nonstationary behavior such as trends in magnitudes through time. Traditional probabilistic analysis of natural hazards based on partial duration series (PDS) generally assumes stationarity in the magnitudes and arrivals of events, i.e. that the probability of exceedance is constant through time. Given evidence of trends and the consequent expected growth in devastating impacts from natural hazards across the world, new methods are needed to characterize their probabilistic behavior. The field of hazard function analysis (HFA) is ideally suited to this problem because its primary goal is to describe changes in the exceedance probability of an event over time. HFA is widely used in medicine, manufacturing, actuarial statistics, reliability engineering, economics, and elsewhere. HFA provides a rich theory to relate the natural hazard event series (x) with its failure time series (t), enabling computation of corresponding average return periods and reliabilities associated with nonstationary event series. This work investigates the suitability of HFA to characterize nonstationary natural hazards whose PDS magnitudes are assumed to follow the widely applied Poisson-GP model. We derive a 2-parameter Generalized Pareto hazard model and demonstrate how metrics such as reliability and average return period are impacted by nonstationarity and discuss the implications for planning and design. Our theoretical analysis linking hazard event series x, with corresponding failure time series t, should have application to a wide class of natural hazards.

Hazard function theory for nonstationary natural hazards

Science.gov (United States)

Read, Laura K.; Vogel, Richard M.

2016-04-01

Impact from natural hazards is a shared global problem that causes tremendous loss of life and property, economic cost, and damage to the environment. Increasingly, many natural processes show evidence of nonstationary behavior including wind speeds, landslides, wildfires, precipitation, streamflow, sea levels, and earthquakes. Traditional probabilistic analysis of natural hazards based on peaks over threshold (POT) generally assumes stationarity in the magnitudes and arrivals of events, i.e., that the probability of exceedance of some critical event is constant through time. Given increasing evidence of trends in natural hazards, new methods are needed to characterize their probabilistic behavior. The well-developed field of hazard function analysis (HFA) is ideally suited to this problem because its primary goal is to describe changes in the exceedance probability of an event over time. HFA is widely used in medicine, manufacturing, actuarial statistics, reliability engineering, economics, and elsewhere. HFA provides a rich theory to relate the natural hazard event series (X) with its failure time series (T), enabling computation of corresponding average return periods, risk, and reliabilities associated with nonstationary event series. This work investigates the suitability of HFA to characterize nonstationary natural hazards whose POT magnitudes are assumed to follow the widely applied generalized Pareto model. We derive the hazard function for this case and demonstrate how metrics such as reliability and average return period are impacted by nonstationarity and discuss the implications for planning and design. Our theoretical analysis linking hazard random variable X with corresponding failure time series T should have application to a wide class of natural hazards with opportunities for future extensions.

Glacier protection laws: Potential conflicts in managing glacial hazards and adapting to climate change.

Science.gov (United States)

Anacona, Pablo Iribarren; Kinney, Josie; Schaefer, Marius; Harrison, Stephan; Wilson, Ryan; Segovia, Alexis; Mazzorana, Bruno; Guerra, Felipe; Farías, David; Reynolds, John M; Glasser, Neil F

2018-03-13

The environmental, socioeconomic and cultural significance of glaciers has motivated several countries to regulate activities on glaciers and glacierized surroundings. However, laws written to specifically protect mountain glaciers have only recently been considered within national political agendas. Glacier Protection Laws (GPLs) originate in countries where mining has damaged glaciers and have been adopted with the aim of protecting the cryosphere from harmful activities. Here, we analyze GPLs in Argentina (approved) and Chile (under discussion) to identify potential environmental conflicts arising from law restrictions and omissions. We conclude that GPLs overlook the dynamics of glaciers and could prevent or delay actions needed to mitigate glacial hazards (e.g. artificial drainage of glacial lakes) thus placing populations at risk. Furthermore, GPL restrictions could hinder strategies (e.g. use of glacial lakes as reservoirs) to mitigate adverse impacts of climate change. Arguably, more flexible GPLs are needed to protect us from the changing cryosphere.

Process safety management for highly hazardous chemicals

Energy Technology Data Exchange (ETDEWEB)

NONE

1996-02-01

Purpose of this document is to assist US DOE contractors who work with threshold quantities of highly hazardous chemicals (HHCs), flammable liquids or gases, or explosives in successfully implementing the requirements of OSHA Rule for Process Safety Management of Highly Hazardous Chemicals (29 CFR 1910.119). Purpose of this rule is to prevent releases of HHCs that have the potential to cause catastrophic fires, explosions, or toxic exposures.

Databases applicable to quantitative hazard/risk assessment-Towards a predictive systems toxicology

International Nuclear Information System (INIS)

Waters, Michael; Jackson, Marcus

2008-01-01

The Workshop on The Power of Aggregated Toxicity Data addressed the requirement for distributed databases to support quantitative hazard and risk assessment. The authors have conceived and constructed with federal support several databases that have been used in hazard identification and risk assessment. The first of these databases, the EPA Gene-Tox Database was developed for the EPA Office of Toxic Substances by the Oak Ridge National Laboratory, and is currently hosted by the National Library of Medicine. This public resource is based on the collaborative evaluation, by government, academia, and industry, of short-term tests for the detection of mutagens and presumptive carcinogens. The two-phased evaluation process resulted in more than 50 peer-reviewed publications on test system performance and a qualitative database on thousands of chemicals. Subsequently, the graphic and quantitative EPA/IARC Genetic Activity Profile (GAP) Database was developed in collaboration with the International Agency for Research on Cancer (IARC). A chemical database driven by consideration of the lowest effective dose, GAP has served IARC for many years in support of hazard classification of potential human carcinogens. The Toxicological Activity Profile (TAP) prototype database was patterned after GAP and utilized acute, subchronic, and chronic data from the Office of Air Quality Planning and Standards. TAP demonstrated the flexibility of the GAP format for air toxics, water pollutants and other environmental agents. The GAP format was also applied to developmental toxicants and was modified to represent quantitative results from the rodent carcinogen bioassay. More recently, the authors have constructed: 1) the NIEHS Genetic Alterations in Cancer (GAC) Database which quantifies specific mutations found in cancers induced by environmental agents, and 2) the NIEHS Chemical Effects in Biological Systems (CEBS) Knowledgebase that integrates genomic and other biological data including

Low level radiation: biological effects

International Nuclear Information System (INIS)

Loken, M.K.

1983-01-01

It is imperative that physicians and scientists using radiations in health care delivery continue to assess the benefits derived, vs. potential risk, to patients and radiation workers being exposed to radiation in its various forms as part of our health delivery system. Insofar as possible we should assure our patients and ourselves that the benefits outweigh the potential hazards involved. Inferences as to the possible biological effects of low level radiation are generally based on extrapolations from those effects observed and measured following acute exposures to considerably higher doses of radiation. Thus, in order to shed light on the question of the possible biological effects of low level radiation, a wide variety of studies have been carried out using cells in culture and various species of plant and animal life. This manuscript makes reference to some of those studies with indications as to how and why the studies were done and the conclusions that might be drawn there from. In addition reference is made to the handling of this information by scientists, by environmentalists, and by the news media. Unfortunately, in many instances the public has been misled by what has been said and/or written. It is hoped that this presentation will provide an understandable and reasonable perspective on the various appropriate uses of radiation in our lives and how such uses do provide significant improvement in our health and in our quality of life

The radiological hazard of plutonium isotopes and specific plutonium mixtures

International Nuclear Information System (INIS)

Heindel, G.; Clow, J.; Inkret, W.; Miller, G.

1995-11-01

The US Department of Energy defines the hazard categories of its nuclear facilities based upon the potential for accidents to have significant effects on specific populations and the environment. In this report, the authors consider the time dependence of hazard category 2 (significant on-site effects) for facilities with inventories of plutonium isotopes and specific weapons-grade and heat-source mixtures of plutonium isotopes. The authors also define relative hazard as the reciprocal of the hazard category 2 threshold value and determine its time dependence. The time dependence of both hazard category 2 thresholds and relative hazards are determined and plotted for 10,000 years to provide useful information for planning long-term storage or disposal facilities

Hazard Characterization of Modified Vaccinia Virus Ankara Vector: What Are the Knowledge Gaps?

Directory of Open Access Journals (Sweden)

Malachy I. Okeke

2017-10-01

Full Text Available Modified vaccinia virus Ankara (MVA is the vector of choice for human and veterinary applications due to its strong safety profile and immunogenicity in vivo. The use of MVA and MVA-vectored vaccines against human and animal diseases must comply with regulatory requirements as they pertain to environmental risk assessment, particularly the characterization of potential adverse effects to humans, animals and the environment. MVA and recombinant MVA are widely believed to pose low or negligible risk to ecosystem health. However, key aspects of MVA biology require further research in order to provide data needed to evaluate the potential risks that may occur due to the use of MVA and MVA-vectored vaccines. The purpose of this paper is to identify knowledge gaps in the biology of MVA and recombinant MVA that are of relevance to its hazard characterization and discuss ongoing and future experiments aimed at providing data necessary to fill in the knowledge gaps. In addition, we presented arguments for the inclusion of uncertainty analysis and experimental investigation of verifiable worst-case scenarios in the environmental risk assessment of MVA and recombinant MVA. These will contribute to improved risk assessment of MVA and recombinant MVA vaccines.

Hazardous waste shipment data collection from DOE sites

International Nuclear Information System (INIS)

Page, L.A.; Kirkpatrick, T.D.; Stevens, L.

1992-01-01

Past practices at the US Department of Energy (DOE) sites for offsite release of hazardous waste are being reviewed to determine if radioactively contaminated hazardous wastes were released to commercial treatment, storage, and disposal facilities. Records indicating the presence of radioactivity in waste shipped to and treated at a commercial incineration facility led to a ban on offsite hazardous waste shipments and investigation of past practices for offsite release of hazardous waste from the DOE sites. A House of Representatives Interior and Insular Affairs Committee oversight hearing on potentially contaminated waste shipments to commercial facilities concluded that the main issue was the lack of a uniform national standard to govern disposal of mixed waste

Potential biological control agents for management of cogongrass (Cyperales: Poaceae) in the southeastern USA

Science.gov (United States)

Cogongrass, Imperata cylindrica (L.) Palisot de Beauvois (Cyperales: Poaceae), is a noxious invasive weed in the southeastern USA. Surveys for potential biological control agents of cogongrass were conducted in Asia and East Africa from 2013 to 2016. Several insect herbivores were found that may hav...

Characterization of the atmospheric pathway at hazardous waste sites

International Nuclear Information System (INIS)

Droppo, J.G. Jr.; Buck, J.W.

1988-10-01

Evaluation of potential health effects for populations surrounding hazardous waste sites requires consideration of all potential contaminant transport pathways through groundwater, surface water, and the atmosphere. A comprehensive pathway model that includes emission, dispersion, and deposition computations has been developed as a component of the Remedial Action Priority System (RAPS). RAPS is designed to assess the relative potential risks associated with hazardous and radioactive mixed-waste disposal sites. The atmospheric component includes optional volatilization and suspension emission routines. Atmospheric transport, dispersion, and deposition are computed using relatively standard modeling techniques expanded to incorporate topographical influences. This sector-averaged Gaussian model accounts for local channeling, terrain heights, and terrain roughness effects. Long-term total deposition is computed for the terrain surrounding the hazardous waste site. An example is given of applications at a US Department of Energy site, where atmospheric emissions are potentially important. The multiple applications of RAPS have provided information on the relative importance of different constitutent transport pathways from a potential population risk basis. Our results show that the atmospheric pathway is often equally as important as other pathways such as groundwater and direct soil ingestion. 6 refs., 3 figs., 4 tabs

Design, Synthesis and Biological Evaluation of Benzohydrazide Derivatives Containing Dihydropyrazoles as Potential EGFR Kinase Inhibitors

Directory of Open Access Journals (Sweden)

Hai-Chao Wang

2016-08-01

Full Text Available A series of novel benzohydrazide derivatives containing dihydropyrazoles have been synthesized as potential epidermal growth factor receptor (EGFR kinase inhibitors and their biological activities as potential antiproliferative agents have been evaluated. Among these compounds, compound H20 exhibited the most potent antiproliferative activity against four cancer cell line variants (A549, MCF-7, HeLa, HepG2 with IC50 values of 0.46, 0.29, 0.15 and 0.21 μM respectively, which showed the most potent EGFR inhibition activities (IC50 = 0.08 μM for EGFR. Molecular modeling simulation studies were performed in order to predict the biological activity and activity relationship (SAR of these benzohydrazide derivatives. These results suggested that compound H20 may be a promising anticancer agent.

Analytical methodologies for aluminium speciation in environmental and biological samples--a review.

Science.gov (United States)

Bi, S P; Yang, X D; Zhang, F P; Wang, X L; Zou, G W

2001-08-01

It is recognized that aluminium (Al) is a potential environmental hazard. Acidic deposition has been linked to increased Al concentrations in natural waters. Elevated levels of Al might have serious consequences for biological communities. Of particular interest is the speciation of Al in aquatic environments, because Al toxicity depends on its forms and concentrations. In this paper, advances in analytical methodologies for Al speciation in environmental and biological samples during the past five years are reviewed. Concerns about the specific problems of Al speciation and highlights of some important methods are elucidated in sections devoted to hybrid techniques (HPLC or FPLC coupled with ET-AAS, ICP-AES, or ICP-MS), flow-injection analysis (FIA), nuclear magnetic resonance (27Al NMR), electrochemical analysis, and computer simulation. More than 130 references are cited.

Hazard identification: A proposal for a new development

International Nuclear Information System (INIS)

Contini, S.; Labath, N.

1989-01-01

Risk assessment is a complex task performed to quantify and minimise the hazards associated with potentially dangerous installations. The hazards identification represents the first step and can be performed by means of different methodologies. Some of these methodologies allow the collection of information on the possible plant behaviours in a structured way. However, this information cannot be easily used for further investigations (i.e. accident quantification). The paper suggests the application of a simple technique for hazard identification and fault tree construction, that can easily be implemented in a computer program. (orig.)

Hazard identification of contaminated sites. Ranking potential toxicity of organic sediment extracts in crustacean and fish

Energy Technology Data Exchange (ETDEWEB)

Karlsson, J.; Sundberg, H.; Aakerman, G.; Grunder, K.; Eklund, B.; Breitholtz, M. [Dept. of Applied Environmental Science (ITM), Stockholm Univ. (Sweden)

2008-09-15

Background, aim, and scope: It is well known that contaminated sediments represent a potential long-term source of pollutants to the aquatic environment. To protect human and ecosystem health, it is becoming common to remediate contaminated sites. However, the great cost associated with, e.g., dredging in combination with the large numbers of contaminated sites makes it crucial to pinpoint those sites that are in greatest need of remediation. In most European countries, this prioritization process has almost exclusively been based on chemical analyses of known substances; only seldom toxicity data has been considered. The main objective of the current study was therefore to develop a tool for hazard identification of sediment by ranking potential toxicity of organic sediment extracts in a crustacean and a fish. A secondary objective was to investigate the difference in potential toxicity between compounds with different polarities. Materials and methods Early life stages of the crustacean Nitocra spinipes and the fish Oncorhynchus mykiss, which represent organisms from different trophic levels (primary and secondary consumer) and with different routes of exposure (i.e. ingestion through food, diffusive uptake, and maternal transfer), were exposed to hexane and acetone fractions (semi-polar compounds) of sediment from five locations, ranging from heavily to low contaminated. Preliminary tests showed that the extracts were non-bioavailable to the crustacean when exposed via water, and the extracts were therefore loaded on silica gel. Rainbow trout embryos were exposed using nano-injection technique. Results and discussion Clear concentration-response relationships of both mortality and larval development were observed in all tests with N. spinipes. Also for rainbow trout, the observed effects (e.g., abnormality, hemorrhage, asymmetric yolk sac) followed a dose-related pattern. Interestingly, our results indicate that some of the locations contained toxic semi

Managing risks and hazardous in industrial operations

Energy Technology Data Exchange (ETDEWEB)

Almaula, S.C. [Woodward-Clyde International, Oakland, CA (United States)

1996-12-31

The main objective of this paper is to demonstrate that it makes good business sense to identify risks and hazards of an operation and take appropriate steps to manage them effectively. Developing and implementing an effective risk and hazard management plan also contibutes to other industry requirements and standards. Development of a risk management system, key elements of a risk management plan, and hazards and risk analysis methods are outlined. Comparing potential risk to the cost of prevention is also discussed. It is estimated that the cost of developing and preparing the first risk management plan varies between $50,000 to $200,000. 3 refs., 2 figs., 1 tab.

Potential application of SERS for arsenic speciation in biological matrices.

Science.gov (United States)

Yang, Mingwei; Matulis, Shannon; Boise, Lawrence H; McGoron, Anthony J; Cai, Yong

2017-08-01

Speciation of arsenic is usually carried out using chromatography-based methods coupled with spectroscopic determination; however, the inevitable procedures involving sample preparation and separation could potentially alter the integrity of the arsenic metabolites present in biological samples. Surface-enhanced Raman spectroscopy (SERS) could be a promising alternative for providing a reliable arsenic analysis under the influence of a cellular matrix. A method for arsenic speciation using SERS in cellular matrix was developed in this study and four arsenicals were selected, including arsenite (As III ), arsenate (As V ), monomethylarsonic acid (MMA V ) and dimethylarsinic acid (DMA V ). Silver nanoparticles in the form of colliodal suspension with different surface charges, i.e., coated with citrate (AgNPs-Citrate) and spermine (AgNPs-Spermine) were employed as SERS substrates. Adsorption of arsenicals on nanoparticles in colloidal suspensions and the cellular matrix and the pH, size, and zeta potential of the colloidal suspensions were investigated for a better understanding of the SERS signal response of arsenicals in the colloidal suspensions or under the influence of cellular matrix. Arsenicals showed substantially different SERS responses in the two colloidal suspensions, mainly because of the distinct difference in the interaction between the arsenicals and the nanoparticles. Arsenic speciation in cell lysate could be successfully carried out in AgNPs-Spermine suspension, while AgNPs-Citrate could not yield significant SERS signals under the experimental conditions. This study proved that AgNPs-Spermine colloidal suspension could be a promising SERS substrate for studying arsenic metabolism in a biological matrix, reducing the bias caused by traditional techniques that involve sample extraction and pretreatment.

Hazardous substances in Europe's fresh and marine waters

DEFF Research Database (Denmark)

Collins, Robert; Brack, Werner; Lützhøft, Hans-Christian Holten

Chemicals are an essential part of our daily lives. They are used to produce consumer goods, to protect or restore our health and to boost food production, to name but a few examples — and they are also involved in a growing range of environmental technologies. Europe's chemical and associated...... on their pattern of use and the potential for exposure. Certain types of naturally occurring chemicals, such as metals, can also be hazardous. Emissions of hazardous substances to the environment can occur at every stage of their life cycle, from production, processing, manufacturing and use in downstream...... regarding chemical contamination arising from the exploitation of shale gas has grown recently. Hazardous substances in water affect aquatic life… Hazardous substances are emitted to water bodies both directly and indirectly through a range of diffuse and point source pathways. The presence of hazardous...

Application of computational systems biology to explore environmental toxicity hazards

DEFF Research Database (Denmark)

Audouze, Karine Marie Laure; Grandjean, Philippe

2011-01-01

Background: Computer-based modeling is part of a new approach to predictive toxicology.Objectives: We investigated the usefulness of an integrated computational systems biology approach in a case study involving the isomers and metabolites of the pesticide dichlorodiphenyltrichloroethane (DDT......) to ascertain their possible links to relevant adverse effects.Methods: We extracted chemical-protein association networks for each DDT isomer and its metabolites using ChemProt, a disease chemical biology database that includes both binding and gene expression data, and we explored protein-protein interactions...... using a human interactome network. To identify associated dysfunctions and diseases, we integrated protein-disease annotations into the protein complexes using the Online Mendelian Inheritance in Man database and the Comparative Toxicogenomics Database.Results: We found 175 human proteins linked to p,p´-DDT...

Tsunami hazard map in eastern Bali

International Nuclear Information System (INIS)

Afif, Haunan; Cipta, Athanasius

2015-01-01

Bali is a popular tourist destination both for Indonesian and foreign visitors. However, Bali is located close to the collision zone between the Indo-Australian Plate and Eurasian Plate in the south and back-arc thrust off the northern coast of Bali resulted Bali prone to earthquake and tsunami. Tsunami hazard map is needed for better understanding of hazard level in a particular area and tsunami modeling is one of the most reliable techniques to produce hazard map. Tsunami modeling conducted using TUNAMI N2 and set for two tsunami sources scenarios which are subduction zone in the south of Bali and back thrust in the north of Bali. Tsunami hazard zone is divided into 3 zones, the first is a high hazard zones with inundation height of more than 3m. The second is a moderate hazard zone with inundation height 1 to 3m and the third is a low tsunami hazard zones with tsunami inundation heights less than 1m. Those 2 scenarios showed southern region has a greater potential of tsunami impact than the northern areas. This is obviously shown in the distribution of the inundated area in the south of Bali including the island of Nusa Penida, Nusa Lembongan and Nusa Ceningan is wider than in the northern coast of Bali although the northern region of the Nusa Penida Island more inundated due to the coastal topography

Tsunami hazard map in eastern Bali

Energy Technology Data Exchange (ETDEWEB)

Afif, Haunan, E-mail: afif@vsi.esdm.go.id [Geological Agency, Bandung (Indonesia); Cipta, Athanasius [Geological Agency, Bandung (Indonesia); Australian National University, Canberra (Australia)

2015-04-24

Bali is a popular tourist destination both for Indonesian and foreign visitors. However, Bali is located close to the collision zone between the Indo-Australian Plate and Eurasian Plate in the south and back-arc thrust off the northern coast of Bali resulted Bali prone to earthquake and tsunami. Tsunami hazard map is needed for better understanding of hazard level in a particular area and tsunami modeling is one of the most reliable techniques to produce hazard map. Tsunami modeling conducted using TUNAMI N2 and set for two tsunami sources scenarios which are subduction zone in the south of Bali and back thrust in the north of Bali. Tsunami hazard zone is divided into 3 zones, the first is a high hazard zones with inundation height of more than 3m. The second is a moderate hazard zone with inundation height 1 to 3m and the third is a low tsunami hazard zones with tsunami inundation heights less than 1m. Those 2 scenarios showed southern region has a greater potential of tsunami impact than the northern areas. This is obviously shown in the distribution of the inundated area in the south of Bali including the island of Nusa Penida, Nusa Lembongan and Nusa Ceningan is wider than in the northern coast of Bali although the northern region of the Nusa Penida Island more inundated due to the coastal topography.

Tsunami hazard map in eastern Bali

Science.gov (United States)

Afif, Haunan; Cipta, Athanasius

2015-04-01

Bali is a popular tourist destination both for Indonesian and foreign visitors. However, Bali is located close to the collision zone between the Indo-Australian Plate and Eurasian Plate in the south and back-arc thrust off the northern coast of Bali resulted Bali prone to earthquake and tsunami. Tsunami hazard map is needed for better understanding of hazard level in a particular area and tsunami modeling is one of the most reliable techniques to produce hazard map. Tsunami modeling conducted using TUNAMI N2 and set for two tsunami sources scenarios which are subduction zone in the south of Bali and back thrust in the north of Bali. Tsunami hazard zone is divided into 3 zones, the first is a high hazard zones with inundation height of more than 3m. The second is a moderate hazard zone with inundation height 1 to 3m and the third is a low tsunami hazard zones with tsunami inundation heights less than 1m. Those 2 scenarios showed southern region has a greater potential of tsunami impact than the northern areas. This is obviously shown in the distribution of the inundated area in the south of Bali including the island of Nusa Penida, Nusa Lembongan and Nusa Ceningan is wider than in the northern coast of Bali although the northern region of the Nusa Penida Island more inundated due to the coastal topography.

Hazard Identification and Risk Assessment in Water Treatment Plant considering Environmental Health and Safety Practice

Directory of Open Access Journals (Sweden)

Falakh Fajrul

2018-01-01

Full Text Available Water Treatment Plant (WTP is an important infrastructure to ensure human health and the environment. In its development, aspects of environmental safety and health are of concern. This paper case study was conducted at the Water Treatment Plant Company in Semarang, Central Java, Indonesia. Hazard identification and risk assessment is one part of the occupational safety and health program at the risk management stage. The purpose of this study was to identify potential hazards using hazard identification methods and risk assessment methods. Risk assessment is done using criteria of severity and probability of accident. The results obtained from this risk assessment are 22 potential hazards present in the water purification process. Extreme categories that exist in the risk assessment are leakage of chlorine and industrial fires. Chlorine and fire leakage gets the highest value because its impact threatens many things, such as industrial disasters that could endanger human life and the environment. Control measures undertaken to avoid potential hazards are to apply the use of personal protective equipment, but management will also be better managed in accordance with hazard control hazards, occupational safety and health programs such as issuing work permits, emergency response training is required, Very useful in overcoming potential hazards that have been determined.

Hazard Identification and Risk Assessment in Water Treatment Plant considering Environmental Health and Safety Practice

Science.gov (United States)

Falakh, Fajrul; Setiani, Onny

2018-02-01

Water Treatment Plant (WTP) is an important infrastructure to ensure human health and the environment. In its development, aspects of environmental safety and health are of concern. This paper case study was conducted at the Water Treatment Plant Company in Semarang, Central Java, Indonesia. Hazard identification and risk assessment is one part of the occupational safety and health program at the risk management stage. The purpose of this study was to identify potential hazards using hazard identification methods and risk assessment methods. Risk assessment is done using criteria of severity and probability of accident. The results obtained from this risk assessment are 22 potential hazards present in the water purification process. Extreme categories that exist in the risk assessment are leakage of chlorine and industrial fires. Chlorine and fire leakage gets the highest value because its impact threatens many things, such as industrial disasters that could endanger human life and the environment. Control measures undertaken to avoid potential hazards are to apply the use of personal protective equipment, but management will also be better managed in accordance with hazard control hazards, occupational safety and health programs such as issuing work permits, emergency response training is required, Very useful in overcoming potential hazards that have been determined.

Biological radiation effects

International Nuclear Information System (INIS)

Kiefer, J.

1989-01-01

The book covers all aspects of biological radiation effects. The physical basis is dealt with in some detail, and the effects at the subcellular and the cellular level are discussed, taking into account modern developments and techniques. The effects on the human organism are reviewed, both from the point of view of applications in medicine as well as with regard to radiation hazards (teratogenic, gonadal and carcinogenic effects)

In situ vitrification applications to hazardous wastes

International Nuclear Information System (INIS)

Liikala, S.

1989-01-01

In Situ Vitrification is a new hazardous waste remediation alternative that should be considered for contaminated soil matrices. According to the authors the advantages of using ISV include: technology demonstrated at field scale; applicable to a wide variety of soils and contaminants; pyrolyzer organics and encapsulates inorganics; product durable over geologic time period; no threat of harm to the public from exposure; and applications available for barrier walls and structural support. The use of ISV on a large scale basis has thus far been limited to the nuclear industry but has tremendous potential for widespread applications to the hazardous waste field. With the ever changing regulations for the disposal of hazardous waste in landfills, and the increasing positive analytical data of ISV, the process will become a powerful source for on-site treatment and hazardous waste management needs in the very near future

Potential of semiautomated, synoptic geologic studies for characterization of hazardous waste sites

International Nuclear Information System (INIS)

Foley, M.G.; Beaver, D.E.; Glennon, M.A.; Eliason, J.R.

1988-01-01

Siting studies for licensing hazardous facilities require three-dimensional characterization of site geology including lithology, structure, and tectonics. The scope of these studies depends on the type of hazardous facility and its associated regulations. This scope can vary from a pro forma literature review to an extensive, multiyear research effort. Further, the regulatory environment often requires that the credibility of such studies be established in administrative and litigative proceedings, rather than solely by technical peer review. Pacific Northwest Laboratory (PNL) has developed a technology called remote geologic analysis (RGA). This technology provides reproducible photogeologic maps, determinations of three- dimensional faults and fracture sets expressed as erosional lineaments or planar topographic features, planar feature identification in seismic hypocenter data, and crustal- stress/tectonic analyses. Results from the RGA establish a foundation for interpretations that are defensible in licensing proceedings

Review of occupational hazards associated with aquaculture.

Science.gov (United States)

Myers, Melvin L

2010-10-01

Aquaculture is an emerging sector that is associated with most of the same hazards that are present in agriculture generally, but many fish farming tasks entail added danger, including working around water and working at night. Comprehensive studies of these hazards have not been conducted, and substantial uncertainty exists as to the extent of these hazards. The question addressed in this investigation was, "What is known about potential hazardous occupational exposures to aquatic plant and animal farmers?" In this review, causes of death included drowning, electrocution, crushing-related injury, hydrogen sulfide poisoning, and fatal head injury. Nonfatal injuries were associated with slips, trips, and falls; machines; strains and sprains; chemicals; and fires. Risk factors included cranes (tip over and power line contact), tractors and sprayer-equipped all-terrain vehicles (overturn), heavy loads (lifting), high-pressure sprayers, slippery surfaces, rotting waste (hydrogen sulfide production), eroding levees (overturn hazard), storm-related rushing water, diving conditions (bends and drowning), nighttime conditions, working alone, lack of training, lack of or failure to use personal flotation devices, and all-terrain vehicle speeding. Other hazards included punctures or cuts from fish teeth or spines, needlesticks, exposure to low temperatures, and bacterial and parasitic infections .

Cleanups In My Community (CIMC) - Hazardous Waste Corrective Actions, National Layer

Data.gov (United States)

U.S. Environmental Protection Agency — This data layer provides access to Hazardous Waste Corrective Action sites as part of the CIMC web service. Hazardous waste is waste that is dangerous or potentially...

Treatment of hazardous organic wastes using silent discharge plasmas

International Nuclear Information System (INIS)

Rosocha, L.A.; Anderson, G.K.; Bechtold, L.A.; Coogan, J.J.; Heck, H.G.; Kang, M.; McCulla, W.H.; Tennant, R.A.; Wantuck, P.J.

1992-01-01

During the past two decades, interest in applying non-equilibrium plasmas to the removal of hazardous chemicals from gaseous media has been growing, in particular from heightened concerns over the pollution of our environment and a growing body of environmental regulations. At the Los Alamos National Laboratory, we are currently engaged in a project to develop non-equilibrium plasma technology for hazardous waste treatment. Our present focus is on dielectric-barrier discharges, which are historically called silent electrical discharges. This type of plasma is also named a silent discharge plasma (SDP). We have chosen this method due to its potential for high energy efficiency, its scientific and technological maturity, and its scalability. The SDP process has been demonstrated to be reliable and economical for the industrial-scale synthesis of ozone, where municipal water treatment plants frequently require the on-site generation of thousands of kilograins per day (Eliasson ampersand Kogelschatz). The related methods of corona processing are presently the focus of work at other institutions, particularly for flue gas processing. Both SDP and corona processes are characterized by the production of large quantities of highly reactive free radicals, especially atomic oxygen O(3P) and the hydroxyl OH, in the gaseous medium and their subsequent reaction with contaminants. Our primary objective is to convert hazardous or toxic chemicals into non-hazardous compounds or into materials which are more amenable to treatment. In the ideal case, the hazardous wastes are destructively oxidized to simpler, non-hazardous compounds plus CO2 and H2O. Sometimes the reaction products are still potentially hazardous, but are easily treated by conventional methods to yield non-hazardous products

The acquisition of dangerous biological materials: Technical facts sheets to assist risk assessments of 46 potential BW agents

Energy Technology Data Exchange (ETDEWEB)

Aceto, Donato Gonzalo [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Astuto-Gribble, Lisa M. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Gaudioso, Jennifer M. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

2007-11-01

Numerous terrorist organizations have openly expressed interest in producing and deploying biological weapons. However, a limiting factor for many terrorists has been the acquisition of dangerous biological agents, as evidenced by the very few successful instances of biological weapons use compared to the number of documented hoaxes. Biological agents vary greatly in their ability to cause loss of life and economic damage. Some agents, if released properly, can kill many people and cause an extensive number of secondary infections; other agents will sicken only a small number of people for a short period of time. Consequently, several biological agents can potentially be used to perpetrate a bioterrorism attack but few are likely capable of causing a high consequence event. It is crucial, from a US national security perspective, to more deeply understand the likelihood that terrorist organizations can acquire the range of these agents. Few studies have attempted to comprehensively compile the technical information directly relevant to the acquisition of dangerous bacteria, viruses and toxins. In this report, technical fact sheets were assembled for 46 potentially dangerous biological agents. Much of the information was taken from various research sources which could ultimately and significantly expedite and improve bioterrorism threat assessments. By systematically examining a number of specific agent characteristics included in these fact sheets, it may be possible to detect, target, and implement measures to thwart future terrorist acquisition attempts. In addition, the information in these fact sheets may be used as a tool to help laboratories gain a rudimentary understanding of how attractive a method laboratory theft is relative to other potential acquisition modes.

Hazard Management Dealt by Safety Professionals in Colleges: The Impact of Individual Factors

Directory of Open Access Journals (Sweden)

Tsung-Chih Wu

2016-12-01

Full Text Available Identifying, evaluating, and controlling workplace hazards are important functions of safety professionals (SPs. The purpose of this study was to investigate the content and frequency of hazard management dealt by safety professionals in colleges. The authors also explored the effects of organizational factors/individual factors on SPs’ perception of frequency of hazard management. The researchers conducted survey research to achieve the objective of this study. The researchers mailed questionnaires to 200 SPs in colleges after simple random sampling, then received a total of 144 valid responses (response rate = 72%. Exploratory factor analysis indicated that the hazard management scale (HMS extracted five factors, including physical hazards, biological hazards, social and psychological hazards, ergonomic hazards, and chemical hazards. Moreover, the top 10 hazards that the survey results identified that safety professionals were most likely to deal with (in order of most to least frequent were: organic solvents, illumination, other chemicals, machinery and equipment, fire and explosion, electricity, noise, specific chemicals, human error, and lifting/carrying. Finally, the results of one-way multivariate analysis of variance (MANOVA indicated there were four individual factors that impacted the perceived frequency of hazard management which were of statistical and practical significance: job tenure in the college of employment, type of certification, gender, and overall job tenure. SPs within colleges and industries can now discuss plans revolving around these five areas instead of having to deal with all of the separate hazards.

Disaster Risks Reduction for Extreme Natural Hazards

Science.gov (United States)

Plag, H.; Jules-Plag, S.

2013-12-01

Mega disasters associated with extreme natural hazards have the potential to escalate the global sustainability crisis and put us close to the boundaries of the safe operating space for humanity. Floods and droughts are major threats that potentially could reach planetary extent, particularly through secondary economic and social impacts. Earthquakes and tsunamis frequently cause disasters that eventually could exceed the immediate coping capacity of the global economy, particularly since we have built mega cities in hazardous areas that are now ready to be harvested by natural hazards. Unfortunately, the more we learn to cope with the relatively frequent hazards (50 to 100 years events), the less we are worried about the low-probability, high-impact events (a few hundred and more years events). As a consequence, threats from the 500 years flood, drought, volcano eruption are not appropriately accounted for in disaster risk reduction (DRR) discussions. Extreme geohazards have occurred regularly throughout the past, but mostly did not cause major disasters because exposure of human assets to hazards was much lower in the past. The most extreme events that occurred during the last 2,000 years would today cause unparalleled damage on a global scale and could worsen the sustainability crisis. Simulation of these extreme hazards under present conditions can help to assess the disaster risk. Recent extreme earthquakes have illustrated the destruction they can inflict, both directly and indirectly through tsunamis. Large volcano eruptions have the potential to impact climate, anthropogenic infrastructure and resource supplies on global scale. During the last 2,000 years several large volcano eruptions occurred, which under today's conditions are associated with extreme disaster risk. The comparison of earthquakes and volcano eruptions indicates that large volcano eruptions are the low-probability geohazards with potentially the highest impact on our civilization

Recognizing Job Health Hazards. Module SH-08. Safety and Health.

Science.gov (United States)

Center for Occupational Research and Development, Inc., Waco, TX.

This student module on recognizing job health hazards is one of 50 modules concerned with job safety and health. This module presents the four general categories of environmental conditions or stresses: chemical, physical, biological, and ergonomic. Following the introduction, 14 objectives (each keyed to a page in the text) the student is…

Hazard and risk of herbicides for marine microalgae

International Nuclear Information System (INIS)

Sjollema, Sascha B.; MartínezGarcía, Gema; Geest, Harm G. van der; Kraak, Michiel H.S.; Booij, Petra; Vethaak, A. Dick; Admiraal, Wim

2014-01-01

Due to their specific effect on photosynthesis, herbicides pose a potential threat to coastal and estuarine microalgae. However, comprehensive understanding of the hazard and risk of these contaminants is currently lacking. Therefore the aim of the present study was to investigate the toxic effects of four ubiquitous herbicides (atrazine, diuron, Irgarol ® 1051 and isoproturon) and herbicide mixtures on marine microalgae. Using a Pulse Amplitude Modulation (PAM) fluorometry based bioassay we demonstrated a clear species and herbicide specific toxicity and showed that the current environmental legislation does not protect algae sufficiently against diuron and isoproturon. Although a low actual risk of herbicides in the field was demonstrated, monitoring data revealed that concentrations occasionally reach potential effect levels. Hence it cannot be excluded that herbicides contribute to observed changes in phytoplankton species composition in coastal waters, but this is likely to occur only occasionally. - Highlights: • The hazard of herbicides for microalgae is compound and species specific. • In general a low risk although occasional potential effect levels are reached. • Current legislation does not protect marine microalgae sufficiently. - The hazard of herbicides in the coastal waters is compound and species specific and although the general risk in the field is low, occasionally potential effect levels are reached

Incineration of hazardous waste: A critical review update

International Nuclear Information System (INIS)

Dempsey, C.R.; Oppelt, E.T.

1993-01-01

Over the last 15 years, concern over improper disposal practices of the past has manifested itself in the passage of a series of federal and state-level hazardous waste cleanup and control statutes of unprecedented scope. The more traditional and lowest-cost methods of direct landfilling, storage in surface impoundments and deep-well injection are being replaced in large measure by waste minimization at the source of generation, waste reuse, physical/chemical/biological treatment, incineration and chemical stabilization/solidification methods. Of all of the 'permanent' treatment technologies, properly designed incineration systems are capable of the highest overall degree of destruction and control for the broadest range of hazardous waste streams. Substantial design and operation experience exists in this area and a wide variety of commercial systems are available. Consequently, significant growth is anticipated in the use of incineration and other thermal destruction methods. The objective of this review is to examine the current state of knowledge regarding hazardous waste incineration in an effort to put these technological and environmental issues into perspective

Causal Mediation Analysis for the Cox Proportional Hazards Model with a Smooth Baseline Hazard Estimator.

Science.gov (United States)

Wang, Wei; Albert, Jeffrey M

2017-08-01

An important problem within the social, behavioral, and health sciences is how to partition an exposure effect (e.g. treatment or risk factor) among specific pathway effects and to quantify the importance of each pathway. Mediation analysis based on the potential outcomes framework is an important tool to address this problem and we consider the estimation of mediation effects for the proportional hazards model in this paper. We give precise definitions of the total effect, natural indirect effect, and natural direct effect in terms of the survival probability, hazard function, and restricted mean survival time within the standard two-stage mediation framework. To estimate the mediation effects on different scales, we propose a mediation formula approach in which simple parametric models (fractional polynomials or restricted cubic splines) are utilized to approximate the baseline log cumulative hazard function. Simulation study results demonstrate low bias of the mediation effect estimators and close-to-nominal coverage probability of the confidence intervals for a wide range of complex hazard shapes. We apply this method to the Jackson Heart Study data and conduct sensitivity analysis to assess the impact on the mediation effects inference when the no unmeasured mediator-outcome confounding assumption is violated.

K Basins fuel encapsulation and storage hazard categorization

International Nuclear Information System (INIS)

Porten, D.R.

1994-12-01

This document establishes the initial hazard categorization for K-Basin fuel encapsulation and storage in the 100 K Area of the Hanford site. The Hazard Categorization for K-Basins addresses the potential for release of radioactive and non-radioactive hazardous material located in the K-Basins and their supporting facilities. The Hazard Categorization covers the hazards associated with normal K-Basin fuel storage and handling operations, fuel encapsulation, sludge encapsulation, and canister clean-up and disposal. The criteria categorizes a facility based on total curies per radionuclide located in the facility. Tables 5-3 and 5-4 display the results in section 5.0. In accordance with DOE-STD-1027 and the analysis provided in section 5.0, the K East Basin fuel encapsulation and storage activity and the K West Basin storage are classified as a open-quotes Category 2close quotes Facility

Risk factors for hazardous events in olfactory-impaired patients.

Science.gov (United States)

Pence, Taylor S; Reiter, Evan R; DiNardo, Laurence J; Costanzo, Richard M

2014-10-01

Normal olfaction provides essential cues to allow early detection and avoidance of potentially hazardous situations. Thus, patients with impaired olfaction may be at increased risk of experiencing certain hazardous events such as cooking or house fires, delayed detection of gas leaks, and exposure to or ingestion of toxic substances. To identify risk factors and potential trends over time in olfactory-related hazardous events in patients with impaired olfactory function. Retrospective cohort study of 1047 patients presenting to a university smell and taste clinic between 1983 and 2013. A total of 704 patients had both clinical olfactory testing and a hazard interview and were studied. On the basis of olfactory function testing results, patients were categorized as normosmic (n = 161), mildly hyposmic (n = 99), moderately hyposmic (n = 93), severely hyposmic (n = 142), and anosmic (n = 209). Patient evaluation including interview, examination, and olfactory testing. Incidence of specific olfaction-related hazardous events (ie, burning pots and/or pans, starting a fire while cooking, inability to detect gas leaks, inability to detect smoke, and ingestion of toxic substances or spoiled foods) by degree of olfactory impairment. The incidence of having experienced any hazardous event progressively increased with degree of impairment: normosmic (18.0%), mildly hyposmic (22.2%), moderately hyposmic (31.2%), severely hyposmic (32.4%), and anosmic (39.2%). Over 3 decades there was no significant change in the overall incidence of hazardous events. Analysis of demographic data (age, sex, race, smoking status, and etiology) revealed significant differences in the incidence of hazardous events based on age (among 397 patients hazardous event, vs 31 of 146 patients ≥65 years [21.3%]; P hazardous event, vs 73 of 265 men [27.6%]; P = .009), and race (among 98 African Americans, 41 [41.8%] with hazardous event, vs 134 of 434 whites [30.9%]; P = .04

EDCs Mixtures: A Stealthy Hazard for Human Health?

Directory of Open Access Journals (Sweden)

Edna Ribeiro

2017-02-01

Full Text Available Endocrine disrupting chemicals (EDCs are exogenous chemicals that may occur naturally (e.g., phytoestrogens, while others are industrial substances and plasticizers commonly utilized worldwide to which human exposure, particularly at low-doses, is omnipresent, persistent and occurs in complex mixtures. EDCs can interfere with/or mimic estrogenic hormones and, consequently, can simultaneously trigger diverse signaling pathways which result in diverse and divergent biological responses. Additionally, EDCs can also bioaccumulate in lipid compartments of the organism forming a mixed “body burden” of contaminants. Although the independent action of chemicals has been considered the main principle in EDCs mixture toxicity, recent studies have demonstrated that numerous effects cannot be predicted when analyzing single compounds independently. Co-exposure to these agents, particularly in critical windows of exposure, may induce hazardous health effects potentially associated with a complex “body burden” of different origins. Here, we performed an exhaustive review of the available literature regarding EDCs mixtures exposure, toxicity mechanisms and effects, particularly at the most vulnerable human life stages. Although the assessment of potential risks to human health due to exposure to EDCs mixtures is a major topic for consumer safety, information regarding effective mixtures effects is still scarce.

Resilience to Interacting multi-natural hazards

Science.gov (United States)

Zhuo, Lu; Han, Dawei

2016-04-01

Conventional analyses of hazard assessment tend to focus on individual hazards in isolation. However, many parts of the world are usually affected by multiple natural hazards with the potential for interacting relationships. The understanding of such interactions, their impacts and the related uncertainties, are an important and topical area of research. Interacting multi-hazards may appear in different forms, including 1) CASCADING HAZARDS (a primary hazard triggering one or more secondary hazards such as an earthquake triggering landslides which may block river channels with dammed lakes and ensued floods), 2) CONCURRING HAZARDS (two or more primary hazards coinciding to trigger or exacerbate secondary hazards such as an earthquake and a rainfall event simultaneously creating landslides), and 3) ALTERING HAZARDS (a primary hazard increasing the probability of a secondary hazard occurring such as major earthquakes disturbing soil/rock materials by violent ground shaking which alter the regional patterns of landslides and debris flows in the subsequent years to come). All three types of interacting multi-hazards may occur in natural hazard prone regions, so it is important that research on hazard resilience should cover all of them. In the past decades, great progresses have been made in tackling disaster risk around the world. However, there are still many challenging issues to be solved, and the disasters over recent years have clearly demonstrated the inadequate resilience in our highly interconnected and interdependent systems. We have identified the following weaknesses and knowledge gaps in the current disaster risk management: 1) although our understanding in individual hazards has been greatly improved, there is a lack of sound knowledge about mechanisms and processes of interacting multi-hazards. Therefore, the resultant multi-hazard risk is often significantly underestimated with severe consequences. It is also poorly understood about the spatial and

Fuels planning: science synthesis and integration; forest structure and fire hazard fact sheet 02: fire hazard

Science.gov (United States)

Rocky Mountain Research Station USDA Forest Service

2004-01-01

Fire hazard reflects the potential fire behavior and magnitude of effects as a function of fuel conditions. This fact sheet discusses crown fuels, surface fuels, and ground fuels and their contribution and involvement in wildland fire.Other publications in this series...

Water reuse potential in truck wash using a Rotating Biological Contactor

Directory of Open Access Journals (Sweden)

Eduardo Lucas Subtil

2016-11-01

Full Text Available This study evaluated the water reuse potential for truck washing using the effluent treated by a Rotating Biological Contactor (RBC operated in full scale. In order to evaluate the reuse potential, a mass balance was performed for the reuse system taking into account the concentration of Total Dissolved Solids as the critical contaminant. The treatment system produced an effluent with average concentration of color, turbidity, TDS and BOD5 of 45 ± 14 uC, 15 ± 6.0 NTU, 244 ± 99 mg TDS / L and 14 ± 7.3 mg O2 / L, respectively. Based on the mass balance, and considering the TDS concentration established in NBR 13.696, if the final rinse does not use clean water, the potential for effluent reuse can reach 40%. However, if clean water is used as 30% of the total rinsing volume, it would be possible to reuse 70% of the treated effluent without compromising truck washing performance. This water reuse approach would result in an operational cost reduction of R$ 2,590.75/month.

Biocides in hydraulic fracturing: hazard and vulnerability with respect to potential groundwater pollution

Science.gov (United States)

Worrall, Fred; Wilson, Miles; Davies, Richard

2016-04-01

Biocides are one possible chemical additive to frack fluids and their role is to control bacterial growth. Bacterial growth might lead to biofilm build up; and acid sulfide species and hydrogen sulfide (H2S) production: biofilm build up may reduce formation permeability and hinder gas extraction. Kahrilas et al. (2014) published a review of common biocides used in fracking in the USA. The biocides assessed in the review were the sixteen most commonly used in the USA, based on the hydraulic fracturing chemical registry Frac Focus (Frac Focus, 2015). However, the review of Kahrilas et al. (2014) contained no data or observations and so the objective of this study was to consider whether biocides proposed for use in hydrofacturing could be a threat to English groundwater. The study considered all groundwater samples analysed for biocides in English groundwater between 2005 and 2014. The monitoring records were compared to: records of application (both amount and area); and chemical and molecular data for the biocides. The study did not use traditional adsorption and degradation data as these parameters are to prone to variability and are not pure molecular parameters. The study then used the approach of Worrall and Thomsen (2004) to consider the hazard represented by proposed frack biocides and the approach of Worrall and Kolpin (2003) to consider the vulnerability of the areas of potential shale gas exploitation. The study showed that of the 113 biocides tested for in English groundwaters in the decade 2005 - 2014 that 95 were detected above 0.1 g/l . Of these 95, 41 were compounds that were not recorded as being applied during the period of record and the detection of these 41 compounds did not decline over the 10 year period which implies very long residence times and that once compounds do pollute an aquifer then they will be a persistent problem. Furthermore, the solubility of the range of biocides used in frack fluids would imply a potentially higher hazard

Sustainable System for Residual Hazards Management

International Nuclear Information System (INIS)

Kevin M. Kostelnik; James H. Clarke; Jerry L. Harbour

2004-01-01

Hazardous, radioactive and other toxic substances have routinely been generated and subsequently disposed of in the shallow subsurface throughout the world. Many of today's waste management techniques do not eliminate the problem, but rather only concentrate or contain the hazardous contaminants. Residual hazards result from the presence of hazardous and/or contaminated material that remains on-site following active operations or the completion of remedial actions. Residual hazards pose continued risk to humans and the environment and represent a significant and chronic problem that require continuous long-term management (i.e. >1000 years). To protect human health and safeguard the natural environment, a sustainable system is required for the proper management of residual hazards. A sustainable system for the management of residual hazards will require the integration of engineered, institutional and land-use controls to isolate residual contaminants and thus minimize the associated hazards. Engineered controls are physical modifications to the natural setting and ecosystem, including the site, facility, and/or the residual materials themselves, in order to reduce or eliminate the potential for exposure to contaminants of concern (COCs). Institutional controls are processes, instruments, and mechanisms designed to influence human behavior and activity. System failure can involve hazardous material escaping from the confinement because of system degradation (i.e., chronic or acute degradation) or by external intrusion of the biosphere into the contaminated material because of the loss of institutional control. An ongoing analysis of contemporary and historic sites suggests that the significance of the loss of institutional controls is a critical pathway because decisions made during the operations/remedial action phase, as well as decisions made throughout the residual hazards management period, are key to the long-term success of the prescribed system. In fact

Building 894 hazards assessment document

International Nuclear Information System (INIS)

Banda, Z.; Williams, M.

1996-07-01

The Department of Energy Order 5500.3A requires facility-specific hazards assessments be prepared, maintained, and used for emergency planning purposes. This hazards assessment document describes the chemical and radiological hazards associated with Building 894. The entire inventory was subjected to the screening criteria for potential airborne impact to onsite and offsite individuals out of which 9 chemicals were kept for further evaluation. The air dispersion model, ALOHA, estimated pollutant concentrations downwind from the source of a release, taking into consideration the toxicological and physical characteristics of the release site, the atmospheric conditions, and the circumstances of the release. The greatest distance at which a postulated facility event will produce consequences exceeding the Early Severe Health Effects threshold is 130 meters. The highest emergency classification is a General Emergency. The Emergency Planning Zone is a nominal 130 meter area that conforms to DOE boundaries and physical/jurisdictional boundaries such as fence lines and streets

Building 6630 hazards assessment document

International Nuclear Information System (INIS)

Williams, M.; Banda, Z.

1996-10-01

The Department of Energy Order 5500.3A requires facility-specific hazards assessments be prepared, maintained, and used for emergency planning purposes. This hazards assessment document describes the chemical and radiological hazards associated with Building 6630. The entire inventory was subjected to the screening criteria for potential airborne impact to onsite and offsite individuals out of which one chemical was kept for further evaluation. The air dispersion model, ALOHA, estimated pollutant concentrations downwind from the source of a release, taking into consideration the toxicological and physical characteristics of the chemical release site, the atmospheric conditions, and the circumstances of the release. The greatest distance at which a postulated facility event will produce consequences exceeding the Early Severe Health Effects threshold is 76 meters. The highest emergency classification is an Alert. The Emergency Planning Zone is a nominal 100 meter area that conforms to DOE boundaries and physical/jurisdictional boundaries such as fence lines and streets

Tank farms hazards assessment

International Nuclear Information System (INIS)

Broz, R.E.

1994-01-01

Hanford contractors are writing new facility specific emergency procedures in response to new and revised US Department of Energy (DOE) Orders on emergency preparedness. Emergency procedures are required for each Hanford facility that has the potential to exceed the criteria for the lowest level emergency, an Alert. The set includes: (1) a facility specific procedure on Recognition and Classification of Emergencies, (2) area procedures on Initial Emergency Response and, (3) an area procedure on Protective Action Guidance. The first steps in developing these procedures are to identify the hazards at each facility, identify the conditions that could release the hazardous material, and calculate the consequences of the releases. These steps are called a Hazards Assessment. The final product is a document that is similar in some respects to a Safety Analysis Report (SAR). The document could br produced in a month for a simple facility but could take much longer for a complex facility. Hanford has both types of facilities. A strategy has been adopted to permit completion of the first version of the new emergency procedures before all the facility hazards Assessments are complete. The procedures will initially be based on input from a task group for each facility. This strategy will but improved emergency procedures in place sooner and therefore enhance Hanford emergency preparedness. The purpose of this document is to summarize the applicable information contained within the Waste Tank Facility ''Interim Safety Basis Document, WHC-SD-WM-ISB-001'' as a resource, since the SARs covering Waste Tank Operations are not current in all cases. This hazards assessment serves to collect, organize, document and present the information utilized during the determination process

Detailed debris flow hazard assessment in Andorra: A multidisciplinary approach

Science.gov (United States)

Hürlimann, Marcel; Copons, Ramon; Altimir, Joan

2006-08-01

In many mountainous areas, the rapid development of urbanisation and the limited space in the valley floors have created a need to construct buildings in zones potentially exposed to debris flow hazard. In these zones, a detailed and coherent hazard assessment is necessary to provide an adequate urban planning. This article presents a multidisciplinary procedure to evaluate the debris flow hazard at a local scale. Our four-step approach was successfully applied to five torrent catchments in the Principality of Andorra, located in the Pyrenees. The first step consisted of a comprehensive geomorphologic and geologic analysis providing an inventory map of the past debris flows, a magnitude-frequency relationship, and a geomorphologic-geologic map. These data were necessary to determine the potential initiation zones and volumes of future debris flows for each catchment. A susceptibility map and different scenarios were the principal outcome of the first step, as well as essential input data for the second step, the runout analysis. A one-dimensional numerical code was applied to analyse the scenarios previously defined. First, the critical channel sections in the fan area were evaluated, then the maximum runout of the debris flows on the fan was studied, and finally simplified intensity maps for each defined scenario were established. The third step of our hazard assessment was the hazard zonation and the compilation of all the results from the two previous steps in a final hazard map. The base of this hazard map was the hazard matrix, which combined the intensity of the debris flow with its probability of occurrence and determined a certain hazard degree. The fourth step referred to the hazard mitigation and included some recommendations for hazard reduction. In Andorra, this four-step approach is actually being applied to assess the debris flow hazard. The final hazard maps, at 1 : 2000 scale, provide an obligatory tool for local land use planning. Experience

Recent advances, and unresolved issues, in the application of computational modelling to the prediction of the biological effects of nanomaterials

International Nuclear Information System (INIS)

Winkler, David A.

2016-01-01

Nanomaterials research is one of the fastest growing contemporary research areas. The unprecedented properties of these materials have meant that they are being incorporated into products very quickly. Regulatory agencies are concerned they cannot assess the potential hazards of these materials adequately, as data on the biological properties of nanomaterials are still relatively limited and expensive to acquire. Computational modelling methods have much to offer in helping understand the mechanisms by which toxicity may occur, and in predicting the likelihood of adverse biological impacts of materials not yet tested experimentally. This paper reviews the progress these methods, particularly those QSAR-based, have made in understanding and predicting potentially adverse biological effects of nanomaterials, and also the limitations and pitfalls of these methods. - Highlights: • Nanomaterials regulators need good information to make good decisions. • Nanomaterials and their interactions with biology are very complex. • Computational methods use existing data to predict properties of new nanomaterials. • Statistical, data driven modelling methods have been successfully applied to this task. • Much more must be learnt before robust toolkits will be widely usable by regulators.

Relationship between the start times of flares and CMEs to the time of potential radiation hazards

Science.gov (United States)

Kang, G.; Zheng, Y.; Kuznetsova, M. M.

2013-12-01

Solar flares, short-term outbursts of energy of the Sun, and coronal mass ejections (CME), massive bursts of solar matter, are two solar phenomena that are known to increase solar energetic particles in space. Increased solar energetic particles cause immense radiation that poses a serious threat to astronauts in space, radio communication signals, and passengers on high-latitude flights on the Earth. The relationship between the start times of flares and CMEs to the time of potential radiation hazards was investigated to determine how much warning time is available. Additionally, this project compared the difference between these relationships for four energy levels of solar energetic particles: proton flux exceeding 10 MeV, 30 MeV, 50 MeV and 100 MeV. This project gathered data of 22 recent SEP events between 2010 and 2012 and the parameters of associated CMEs and flares. Through the use of IDL (Interactive Data Language) programming, thorough analysis was conducted, including 2-sample t-tests and Kruskal-Wallis tests for 2 or more samples. The average lead time to warn humans of possible radiation hazard from the detection of a flare and a CME occurrence was found to be around 12 to 20 hours. The lead time was the greatest for the lowest energy level, though the differences in energy levels and that between the lead times for CME and flares were found to be statistically insignificant with p-values exceeding the alpha value of 0.20.

Washington Tsunami Hazard Mitigation Program

Science.gov (United States)

Walsh, T. J.; Schelling, J.

2012-12-01

Washington State has participated in the National Tsunami Hazard Mitigation Program (NTHMP) since its inception in 1995. We have participated in the tsunami inundation hazard mapping, evacuation planning, education, and outreach efforts that generally characterize the NTHMP efforts. We have also investigated hazards of significant interest to the Pacific Northwest. The hazard from locally generated earthquakes on the Cascadia subduction zone, which threatens tsunami inundation in less than hour following a magnitude 9 earthquake, creates special problems for low-lying accretionary shoreforms in Washington, such as the spits of Long Beach and Ocean Shores, where high ground is not accessible within the limited time available for evacuation. To ameliorate this problem, we convened a panel of the Applied Technology Council to develop guidelines for construction of facilities for vertical evacuation from tsunamis, published as FEMA 646, now incorporated in the International Building Code as Appendix M. We followed this with a program called Project Safe Haven (http://www.facebook.com/ProjectSafeHaven) to site such facilities along the Washington coast in appropriate locations and appropriate designs to blend with the local communities, as chosen by the citizens. This has now been completed for the entire outer coast of Washington. In conjunction with this effort, we have evaluated the potential for earthquake-induced ground failures in and near tsunami hazard zones to help develop cost estimates for these structures and to establish appropriate tsunami evacuation routes and evacuation assembly areas that are likely to to be available after a major subduction zone earthquake. We intend to continue these geotechnical evaluations for all tsunami hazard zones in Washington.

Hazard screening application guide. Safety Analysis Report Update Program

Energy Technology Data Exchange (ETDEWEB)

None

1992-06-01

The basic purpose of hazard screening is to group precesses, facilities, and proposed modifications according to the magnitude of their hazards so as to determine the need for and extent of follow on safety analysis. A hazard is defined as a material, energy source, or operation that has the potential to cause injury or illness in human beings. The purpose of this document is to give guidance and provide standard methods for performing hazard screening. Hazard screening is applied to new and existing facilities and processes as well as to proposed modifications to existing facilities and processes. The hazard screening process evaluates an identified hazards in terms of the effects on people, both on-site and off-site. The process uses bounding analyses with no credit given for mitigation of an accident with the exception of certain containers meeting DOT specifications. The process is restricted to human safety issues only. Environmental effects are addressed by the environmental program. Interfaces with environmental organizations will be established in order to share information.

Evaluation of seismic hazards for nuclear power plants. Safety guide

International Nuclear Information System (INIS)

2002-01-01

The main objective of this Safety Guide is to provide recommendations on how to determine the ground motion hazards for a plant at a particular site and the potential for surface faulting, which could affect the feasibility of construction and safe operation of a plant at that site. The guidelines and procedures presented in this Safety Guide can appropriately be used in evaluations of site suitability and seismic hazards for nuclear power plants in any seismotectonic environment. The probabilistic seismic hazard analysis recommended in this Safety Guide also addresses the needs for seismic hazard analysis of external event PSAs conducted for nuclear power plants. Many of the methods and processes described may also be applicable to nuclear facilities other than power plants. Other phenomena of permanent ground displacement (liquefaction, slope instability, subsidence and collapse) as well as the topic of seismically induced flooding are treated in Safety Guides relating to foundation safety and coastal flooding. Recommendations of a general nature are given in Section 2. Section 3 discusses the acquisition of a database containing the information needed to evaluate and address all hazards associated with earthquakes. Section 4 covers the use of this database for construction of a seismotectonic model. Sections 5 and 6 review ground motion hazards and evaluations of the potential for surface faulting, respectively. Section 7 addresses quality assurance in the evaluation of seismic hazards for nuclear power plants

Advanced Materials Laboratory hazards assessment document

Energy Technology Data Exchange (ETDEWEB)

Barnett, B.; Banda, Z.

1995-10-01

The Department of Energy Order 55OO.3A requires facility-specific hazards assessments be prepared, maintained, and used for emergency planning purposes. This hazards assessment document describes the chemical and radiological hazards associated with the AML. The entire inventory was screened according to the potential airborne impact to onsite and offsite individuals. The air dispersion model, ALOHA, estimated pollutant concentrations downwind from the source of a release, taking into consideration the toxicological and physical characteristics of the release site, the atmospheric conditions, and the circumstances of the release. The greatest distance at which a postulated facility event will produce consequences exceeding the Early Severe Health Effects threshold is 23 meters. The highest emergency classification is a General Emergency. The Emergency Planning Zone is a nominal area that conforms to DOE boundaries and physical/jurisdictional boundaries such as fence lines and streets.

Advanced Manufacturing Processes Laboratory Building 878 hazards assessment document

Energy Technology Data Exchange (ETDEWEB)

Wood, C.; Thornton, W.; Swihart, A.; Gilman, T.

1994-07-01

The introduction of the hazards assessment process is to document the impact of the release of hazards at the Advanced Manufacturing Processes Laboratory (AMPL) that are significant enough to warrant consideration in Sandia National Laboratories` operational emergency management program. This hazards assessment is prepared in accordance with the Department of Energy Order 5500.3A requirement that facility-specific hazards assessments be prepared, maintained, and used for emergency planning purposes. This hazards assessment provides an analysis of the potential airborne release of chemicals associated with the operations and processes at the AMPL. This research and development laboratory develops advanced manufacturing technologies, practices, and unique equipment and provides the fabrication of prototype hardware to meet the needs of Sandia National Laboratories, Albuquerque, New Mexico (SNL/NM). The focus of the hazards assessment is the airborne release of materials because this requires the most rapid, coordinated emergency response on the part of the AMPL, SNL/NM, collocated facilities, and surrounding jurisdiction to protect workers, the public, and the environment.

Advanced Manufacturing Processes Laboratory Building 878 hazards assessment document

International Nuclear Information System (INIS)

Wood, C.; Thornton, W.; Swihart, A.; Gilman, T.

1994-07-01

The introduction of the hazards assessment process is to document the impact of the release of hazards at the Advanced Manufacturing Processes Laboratory (AMPL) that are significant enough to warrant consideration in Sandia National Laboratories' operational emergency management program. This hazards assessment is prepared in accordance with the Department of Energy Order 5500.3A requirement that facility-specific hazards assessments be prepared, maintained, and used for emergency planning purposes. This hazards assessment provides an analysis of the potential airborne release of chemicals associated with the operations and processes at the AMPL. This research and development laboratory develops advanced manufacturing technologies, practices, and unique equipment and provides the fabrication of prototype hardware to meet the needs of Sandia National Laboratories, Albuquerque, New Mexico (SNL/NM). The focus of the hazards assessment is the airborne release of materials because this requires the most rapid, coordinated emergency response on the part of the AMPL, SNL/NM, collocated facilities, and surrounding jurisdiction to protect workers, the public, and the environment

Hazard Evaluation for Storage of Spent Nuclear Fuel (SNF) Sludge at the Solid Waste Treatment Facility

International Nuclear Information System (INIS)

SCHULTZ, M.V.

2000-01-01

As part of the Spent Nuclear Fuel (SNF) storage basin clean-up project, sludge that has accumulated in the K Basins due to corrosion of damaged irradiated N Reactor will be loaded into containers and placed in interim storage. The Hanford Site Treatment Complex (T Plant) has been identified as the location where the sludge will be stored until final disposition of the material occurs. Long term storage of sludge from the K Basin fuel storage facilities requires identification and analysis of potential accidents involving sludge storage in T Plant. This report is prepared as the initial step in the safety assurance process described in DOE Order 5480.23, Nuclear Safety Analysis Reports and HNF-PRO-704, Hazards and Accident Analysis Process. This report documents the evaluation of potential hazards and off-normal events associated with sludge storage activities. This information will be used in subsequent safety analyses, design, and operations procedure development to ensure safe storage. The hazards evaluation for the storage of SNF sludge in T-Plant used the Hazards and Operability Analysis (HazOp) method. The hazard evaluation identified 42 potential hazardous conditions. No hazardous conditions involving hazardous/toxic chemical concerns were identified. Of the 42 items identified in the HazOp study, eight were determined to have potential for onsite worker consequences. No items with potential offsite consequences were identified in the HazOp study. Hazardous conditions with potential onsite worker or offsite consequences are candidates for quantitative consequence analysis. The hazardous conditions with potential onsite worker consequences were grouped into two event categories, Container failure due to overpressure - internal to T Plant, and Spill of multiple containers. The two event categories will be developed into accident scenarios that will be quantitatively analyzed to determine release consequences. A third category, Container failure due to

Potential of development of the mechanical-biological waste treatment; Entwicklungspotenzial der Mechanisch-Biologischen Abfallbehandlung

Energy Technology Data Exchange (ETDEWEB)

Grundmann, Thomas; Balhar, Michael [ASA e.V., Ennigerloh (Germany); Abfallwirtschaftsgesellschaft des Kreises Warendorf mbH, Ennigerloh (Germany)

2013-03-01

The Consortium Material-Specific Waste Treatment eV (Ennigerloh, Federal Republic of Germany) is an association of plant operators having the opinion that an economic and ecologic waste treatment only can be guaranteed by material-specific processes permanently. Due to the specific treatment processes in plants with mechanical-biological waste treatment (MBA) material flows are resulting being available for the recycling or exploitation. Under this aspect, the authors of the contribution under consideration report on the development potential of the mechanical-biological waste treatment. The state of the art of the technology of mechanical-biological waste treatment in Germany as well as the contribution of this technology to the resource protection and climate protection are described. Further aspects of this contribution are the increase of the energy efficiency and reduction of emissions; further development of the efficient sorting technology; development of integrated total conceptions - MBA-sites as centres for the production of renewable energies.

Can hazard risk be communicated through a virtual experience?

Science.gov (United States)

Mitchell, J T

1997-09-01

Cyberspace, defined by William Gibson as a consensual hallucination, now refers to all computer-generated interactive environments. Virtual reality, one of a class of interactive cyberspaces, allows us to create and interact directly with objects not available in the everyday world. Despite successes in the entertainment and aviation industries, this technology has been called a 'solution in search of a problem'. The purpose of this commentary is to suggest such a problem: the inability to acquire experience with a hazard to motivate mitigation. Direct experience with a hazard has been demonstrated as a powerful incentive to adopt mitigation measures. While we lack the ability to summon hazard events at will in order to gain access to that experience, a virtual environment can provide an arena where potential victims are exposed to a hazard's effects. Immersion as an active participant within the hazard event through virtual reality may stimulate users to undertake mitigation steps that might otherwise remain undone. This paper details the possible direction in which virtual reality may be applied to hazards mitigation through a discussion of the technology, the role of hazard experience, the creation of a hazard stimulation and the issues constraining implementation.

Hazard Analysis for Pneumatic Flipper Suitport/Z-1 Manned Evaluation, Chamber B, Building 32. Revision: Basic

Science.gov (United States)

2012-01-01

One of the characteristics of an effective safety program is the recognition and control of hazards before mishaps or failures occur. Conducting potentially hazardous tests necessitates a thorough hazard analysis in order to protect our personnel from injury and our equipment from damage. The purpose of this hazard analysis is to define and address the potential hazards and controls associated with the Z1 Suit Port Test in Chamber B located in building 32, and to provide the applicable team of personnel with the documented results. It is imperative that each member of the team be familiar with the hazards and controls associated with his/her particular tasks, assignments, and activities while interfacing with facility test systems, equipment, and hardware. The goal of this hazard analysis is to identify all hazards that have the potential to harm personnel and/or damage facility equipment, flight hardware, property, or harm the environment. This analysis may also assess the significance and risk, when applicable, of lost test objectives when substantial monetary value is involved. The hazards, causes, controls, verifications, and risk assessment codes have been documented on the hazard analysis work sheets in appendix A of this document. The preparation and development of this report is in accordance with JPR 1700.1, JSC Safety and Health Handbook.

Assessment of the potential respiratory hazard of volcanic ash from future Icelandic eruptions: a study of archived basaltic to rhyolitic ash samples.

Science.gov (United States)

Damby, David E; Horwell, Claire J; Larsen, Gudrun; Thordarson, Thorvaldur; Tomatis, Maura; Fubini, Bice; Donaldson, Ken

2017-09-11

The eruptions of Eyjafjallajökull (2010) and Grímsvötn (2011), Iceland, triggered immediate, international consideration of the respiratory health hazard of inhaling volcanic ash, and prompted the need to estimate the potential hazard posed by future eruptions of Iceland's volcanoes to Icelandic and Northern European populations. A physicochemical characterization and toxicological assessment was conducted on a suite of archived ash samples spanning the spectrum of past eruptions (basaltic to rhyolitic magmatic composition) of Icelandic volcanoes following a protocol specifically designed by the International Volcanic Health Hazard Network. Icelandic ash can be of a respirable size (up to 11.3 vol.% fiber-like particles were observed, but those present comprised glass or sodium oxides, and are not related to pathogenic natural fibers, like asbestos or fibrous zeolites, thereby limiting concern of associated respiratory diseases. None of the samples contained cristobalite or tridymite, and only one sample contained quartz, minerals of interest due to the potential to cause silicosis. Sample surface areas are low, ranging from 0.4 to 1.6 m 2  g -1 , which aligns with analyses on ash from other eruptions worldwide. All samples generated a low level of hydroxyl radicals (HO • ), a measure of surface reactivity, through the iron-catalyzed Fenton reaction compared to concurrently analyzed comparative samples. However, radical generation increased after 'refreshing' sample surfaces, indicating that newly erupted samples may display higher reactivity. A composition-dependent range of available surface iron was measured after a 7-day incubation, from 22.5 to 315.7 μmol m -2 , with mafic samples releasing more iron than silicic samples. All samples were non-reactive in a test of red blood cell-membrane damage. The primary particle-specific concern is the potential for future eruptions of Iceland's volcanoes to generate fine, respirable material and, thus, to

Geologic Maps as the Foundation of Mineral-Hazards Maps in California

Science.gov (United States)

Higgins, C. T.; Churchill, R. K.; Downey, C. I.; Clinkenbeard, J. P.; Fonseca, M. C.

2010-12-01

The basic geologic map is essential to the development of products that help planners, engineers, government officials, and the general public make decisions concerning natural hazards. Such maps are the primary foundation that the California Geological Survey (CGS) uses to prepare maps that show potential for mineral-hazards. Examples of clients that request these maps are the California Department of Transportation (Caltrans) and California Department of Public Health (CDPH). Largely because of their non-catastrophic nature, mineral hazards have received much less public attention compared to earthquakes, landslides, volcanic eruptions, and floods. Nonetheless, mineral hazards can be a major concern locally when considering human health and safety and potential contamination of the environment by human activities such as disposal of earth materials. To address some of these concerns, the CGS has focused its mineral-hazards maps on naturally occurring asbestos (NOA), radon, and various potentially toxic metals as well as certain artificial features such as mines and oil and gas wells. The maps range in scope from statewide to counties and Caltrans districts to segments of selected highways. To develop the hazard maps, the CGS begins with traditional paper and digital versions of basic geologic maps, which are obtained from many sources such as its own files, the USGS, USDA Forest Service, California Department of Water Resources, and counties. For each study area, these maps present many challenges of compilation related to vintage, scale, definition of units, and edge-matching across map boundaries. The result of each CGS compilation is a digital geologic layer that is subsequently reinterpreted and transformed into new digital layers (e.g., lithologic) that focus on the geochemical and mineralogical properties of the area’s earth materials and structures. These intermediate layers are then integrated with other technical data to derive final digital layers

PUREX facility hazards assessment

International Nuclear Information System (INIS)

Sutton, L.N.

1994-01-01

This report documents the hazards assessment for the Plutonium Uranium Extraction Plant (PUREX) located on the US Department of Energy (DOE) Hanford Site. Operation of PUREX is the responsibility of Westinghouse Hanford Company (WHC). This hazards assessment was conducted to provide the emergency planning technical basis for PUREX. DOE Order 5500.3A requires an emergency planning hazards assessment for each facility that has the potential to reach or exceed the lowest level emergency classification. In October of 1990, WHC was directed to place PUREX in standby. In December of 1992 the DOE Assistant Secretary for Environmental Restoration and Waste Management authorized the termination of PUREX and directed DOE-RL to proceed with shutdown planning and terminal clean out activities. Prior to this action, its mission was to reprocess irradiated fuels for the recovery of uranium and plutonium. The present mission is to establish a passively safe and environmentally secure configuration at the PUREX facility and to preserve that condition for 10 years. The ten year time frame represents the typical duration expended to define, authorize and initiate follow-on decommissioning and decontamination activities

TCA Cycle and Mitochondrial Membrane Potential Are Necessary for Diverse Biological Functions.

Science.gov (United States)

Martínez-Reyes, Inmaculada; Diebold, Lauren P; Kong, Hyewon; Schieber, Michael; Huang, He; Hensley, Christopher T; Mehta, Manan M; Wang, Tianyuan; Santos, Janine H; Woychik, Richard; Dufour, Eric; Spelbrink, Johannes N; Weinberg, Samuel E; Zhao, Yingming; DeBerardinis, Ralph J; Chandel, Navdeep S

2016-01-21

Mitochondrial metabolism is necessary for the maintenance of oxidative TCA cycle function and mitochondrial membrane potential. Previous attempts to decipher whether mitochondria are necessary for biological outcomes have been hampered by genetic and pharmacologic methods that simultaneously disrupt multiple functions linked to mitochondrial metabolism. Here, we report that inducible depletion of mitochondrial DNA (ρ(ο) cells) diminished respiration, oxidative TCA cycle function, and the mitochondrial membrane potential, resulting in diminished cell proliferation, hypoxic activation of HIF-1, and specific histone acetylation marks. Genetic reconstitution only of the oxidative TCA cycle function specifically in these inducible ρ(ο) cells restored metabolites, resulting in re-establishment of histone acetylation. In contrast, genetic reconstitution of the mitochondrial membrane potential restored ROS, which were necessary for hypoxic activation of HIF-1 and cell proliferation. These results indicate that distinct mitochondrial functions associated with respiration are necessary for cell proliferation, epigenetics, and HIF-1 activation. Copyright © 2016 Elsevier Inc. All rights reserved.

Biological Risks and Laboratory-Acquired Infections: A Reality That Cannot be Ignored in Health Biotechnology

Science.gov (United States)

Coelho, Ana Cláudia; García Díez, Juan

2015-01-01

Advances and research in biotechnology have applications over a wide range of areas, such as microbiology, medicine, the food industry, agriculture, genetically modified organisms, and nanotechnology, among others. However, research with pathogenic agents, such as virus, parasites, fungi, rickettsia, bacterial microorganisms, or genetic modified organisms, has generated concern because of their potential biological risk – not only for people, but also for the environment due to their unpredictable behavior. In addition, concern for biosafety is associated with the emergence of new diseases or re-emergence of diseases that were already under control. Biotechnology laboratories require biosafety measures designed to protect their staff, the population, and the environment, which may be exposed to hazardous organisms and materials. Laboratory staff training and education is essential, not only to acquire a good understanding about the direct handling of hazardous biological agents but also knowledge of the epidemiology, pathogenicity, and human susceptibility to the biological materials used in research. Biological risk can be reduced and controlled by the correct application of internationally recognized procedures such as proper microbiological techniques, proper containment apparatus, adequate facilities, protective barriers, and special training and education of laboratory workers. To avoid occupational infections, knowledge about standardized microbiological procedures and techniques and the use of containment devices, facilities, and protective barriers is necessary. Training and education about the epidemiology, pathogenicity, and biohazards of the microorganisms involved may prevent or decrease the risk. In this way, the scientific community may benefit from the lessons learned in the past to anticipate future problems. PMID:25973418

Biological risks and laboratory-acquired infections. A reality that cannot be ignored in health biotechnology

Directory of Open Access Journals (Sweden)

Ana Cláudia Coelho

2015-04-01

Full Text Available Advances and research in biotechnology have applications over a wide range of areas such as microbiology, medicine, the food industry, agriculture, genetically modified organisms and nanotechnology, among others. However, research with pathogenic agents such as virus, parasites, fungi, rickettsia, bacterial microorganisms or genetic modified organisms has generated concern because of their potential biological risk - not only for people, but also for the environment due to their unpredictable behavior. In addition, concern for biosafety is associated with the emergence of new diseases or re-emergence of diseases that were already under control. Biotechnology laboratories require biosafety measures designed to protect their staff, the population and the environment, which may be exposed to hazardous organisms and materials. Laboratory staff training and education is essential, not only to acquire a good understanding about the direct handling of hazardous biological agents but also knowledge of the epidemiology, pathogenicity and human susceptibility to the biological materials used in research. Biological risk can be reduced and controlled by the correct application of internationally recognized procedures such as proper microbiological techniques, proper containment apparatus, adequate facilities, protective barriers and special training and education of laboratory workers. To avoid occupational infections, knowledge about standardized microbiological procedures and techniques and the use of containment devices, facilities and protective barriers is necessary. Training and education about the epidemiology, pathogenicity and biohazards of the microorganisms involved may prevent or decrease the risk. In this way, the scientific community may benefit from the lessons learned in the past to anticipate future problems.

Criteria and Processes for the Certification of Non-Radioactive Hazardous and Non-Hazardous Wastes

International Nuclear Information System (INIS)

Dominick, J.

2008-01-01

This document details Lawrence Livermore National Laboratory's (LLNL) criteria and processes for determining if potentially volumetrically contaminated or potentially surface contaminated wastes are to be managed as material containing residual radioactivity or as non-radioactive. This document updates and replaces UCRL-AR-109662, Criteria and Procedures for the Certification of Nonradioactive Hazardous Waste (Reference 1), also known as 'The Moratorium', and follows the guidance found in the U.S. Department of Energy (DOE) document, Performance Objective for Certification of Non-Radioactive Hazardous Waste (Reference 2). The 1992 Moratorium document (UCRL-AR-109662) is three volumes and 703 pages. The first volume provides an overview of the certification process and lists the key radioanalytical methods and their associated Limits of Sensitivities. Volumes Two and Three contain supporting documents and include over 30 operating procedures, QA plans, training documents and organizational charts that describe the hazardous and radioactive waste management system in place in 1992. This current document is intended to update the previous Moratorium documents and to serve as the top-tier LLNL institutional Moratorium document. The 1992 Moratorium document was restricted to certification of Resource Conservation and Recovery Act (RCRA), State and Toxic Substances Control Act (TSCA) hazardous waste from Radioactive Material Management Areas (RMMA). This still remains the primary focus of the Moratorium; however, this document increases the scope to allow use of this methodology to certify other LLNL wastes and materials destined for off-site disposal, transfer, and re-use including non-hazardous wastes and wastes generated outside of RMMAs with the potential for DOE added radioactivity. The LLNL organization that authorizes off-site transfer/disposal of a material or waste stream is responsible for implementing the requirements of this document. The LLNL Radioactive and

The potential role of earthworms in toxicity assessment of terrestrial hazardous waste sites

Energy Technology Data Exchange (ETDEWEB)

Goven, A.J.; Fitzpatrick, L.C. [Univ. of North Texas, Denton, TX (United States); Venables, B.J. [TRAC Labs., Inc., Denton, TX (United States)

1994-12-31

Understanding the toxic potential and mechanisms of action of environmental xenobiotics is fundamental for assessing risk to public and environmental health. Current established protocols with earthworms focus primarily on defining the lethal effects of chemicals associated with soil contamination. Development of sublethal assays, until recently, has been largely ignored. Here the authors develop rationale for use of earthworms as a model organism for comprehensive assessment of risks to higher wildlife from contaminated soils and hazardous waste sites. They present a panel of lethal (LC/LD50`s) and sublethal measurement endpoint biomarkers, developed within the framework of the National Toxicology Program`s tiered immunotoxicity protocol for mice and according to published criteria for good measurement endpoints, that represent sensitive phylogenetically-conserved processes. Specifically the authors discuss immunosuppressive effects of terrestrial heavy metal and organic contamination on the innate, nonspecific and specific immune responses of earthworm, Lumbricus terrestris, coelomocytes in terms of total and differential cell counts, lysozyme activity, nitroblue tetrazolium dye reduction, phagocytic activity and secretary rosette formation. Findings indicate that sensitive phylogenetically conserved immune responses present in invertebrates can be used to assess or predict risk to wildlife from contaminated soils.

Screening criteria of volcanic hazards aspect in the NPP site evaluation

International Nuclear Information System (INIS)

Nur Siwhan

2013-01-01

Studies have been conducted on the completeness of regulation in Indonesia particularly on volcanic hazards aspects in the evaluation of nuclear power plant site. Volcanic hazard aspect needed to identify potential external hazards that may endanger the safety of the operation of nuclear power plants. There are four stages for evaluating volcanic hazards, which are initial assessment, characterization sources of volcanic activity in the future, screening volcanic hazards and assessment of capable volcanic hazards. This paper discuss the third stage of the general evaluation which is the screening procedure of volcanic hazards. BAPETEN Chairman Regulation No. 2 Year of 2008 has only one screening criteria for missile volcanic phenomena, so it required screening criteria for other hazard phenomena that are pyroclastic flow density; lava flows; avalanche debris materials; lava; opening hole new eruptions, volcano missile; tsunamis; ground deformation; and hydrothermal system and ground water anomaly. (author)

Applying the Nernst equation to simulate redox potential variations for biological nitrification and denitrification processes.

Science.gov (United States)

Chang, Cheng-Nan; Cheng, Hong-Bang; Chao, Allen C

2004-03-15

In this paper, various forms of Nernst equations have been developed based on the real stoichiometric relationship of biological nitrification and denitrification reactions. Instead of using the Nernst equation based on a one-to-one stoichiometric relation for the oxidizing and the reducing species, the basic Nernst equation is modified into slightly different forms. Each is suitable for simulating the redox potential (ORP) variation of a specific biological nitrification or denitrification process. Using the data published in the literature, the validity of these developed Nernst equations has been verified by close fits of the measured ORP data with the calculated ORP curve. The simulation results also indicate that if the biological process is simulated using an incorrect form of Nernst equation, the calculated ORP curve will not fit the measured data. Using these Nernst equations, the ORP value that corresponds to a predetermined degree of completion for the biochemical reaction can be calculated. Thus, these Nernst equations will enable a more efficient on-line control of the biological process.

Hazardous material reduction initiative

International Nuclear Information System (INIS)

Nichols, D.H.

1995-02-01

The Hazardous Material Reduction Initiative (HMRI) explores using the review of purchase requisitions to reduce both the use of hazardous materials and the generation of regulated and nonregulated wastes. Based on an 11-month program implemented at the Hanford Site, hazardous material use and waste generation was effectively reduced by using a centralized procurement control program known as HMRI. As expected, several changes to the original proposal were needed during the development/testing phase of the program to accommodate changing and actual conditions found at the Hanford Site. The current method requires a central receiving point within the Procurement Organization to review all purchase requisitions for potentially Occupational Safety and Health Administration (OSHA) hazardous products. Those requisitions (approximately 4% to 6% of the total) are then forwarded to Pollution Prevention personnel for evaluation under HMRI. The first step is to determine if the requested item can be filled by existing or surplus material. The requisitions that cannot filled by existing or surplus material are then sorted into two groups based on applicability to the HMRI project. For example, laboratory requests for analytical reagents or standards are excluded and the purchase requisitions are returned to Procurement for normal processing because, although regulated, there is little opportunity for source reduction due to the strict protocols followed. Each item is then checked to determine if it is regulated or not. Regulated items are prioritized based on hazardous contents, quantity requested, and end use. Copies of these requisitions are made and the originals are returned to Procurement within 1-hr. Since changes to the requisition can be made at later stages during procurement, the HMRI fulfills one of its original premises in that it does not slow the procurement process

Multi-hazard risk assessment applied to hydraulic fracturing operations

Science.gov (United States)

Garcia-Aristizabal, Alexander; Gasparini, Paolo; Russo, Raffaella; Capuano, Paolo

2017-04-01

Without exception, the exploitation of any energy resource produces impacts and intrinsically bears risks. Therefore, to make sound decisions about future energy resource exploitation, it is important to clearly understand the potential environmental impacts in the full life-cycle of an energy development project, distinguishing between the specific impacts intrinsically related to exploiting a given energy resource and those shared with the exploitation of other energy resources. Technological advances as directional drilling and hydraulic fracturing have led to a rapid expansion of unconventional resources (UR) exploration and exploitation; as a consequence, both public health and environmental concerns have risen. The main objective of a multi-hazard risk assessment applied to the development of UR is to assess the rate (or the likelihood) of occurrence of incidents and the relative potential impacts on surrounding environment, considering different hazards and their interactions. Such analyses have to be performed considering the different stages of development of a project; however, the discussion in this paper is mainly focused on the analysis applied to the hydraulic fracturing stage of a UR development project. The multi-hazard risk assessment applied to the development of UR poses a number of challenges, making of this one a particularly complex problem. First, a number of external hazards might be considered as potential triggering mechanisms. Such hazards can be either of natural origin or anthropogenic events caused by the same industrial activities. Second, failures might propagate through the industrial elements, leading to complex scenarios according to the layout of the industrial site. Third, there is a number of potential risk receptors, ranging from environmental elements (as the air, soil, surface water, or groundwater) to local communities and ecosystems. The multi-hazard risk approach for this problem is set by considering multiple hazards

Everyday food is safe! Consumer versus expert hazard identification of two novel foods

DEFF Research Database (Denmark)

Hagemann, Kit

Novel foods have been the object of intense public debate in recent years. Despite efforts to communicate the outcomes of risk assessments to consumers, public confidence in the management of potential risks associated has been low. Various reasons behind this has identified, chiefly a disagreement...... in terms of detailed chains of cause-effect relationships, but consumers used abstract concepts when they reasoned about biological processes. Outcome uncertainty played an enormous role in consumers' perception of risk, which was in contrast to experts, who often declined to elaborate on consequences...... between technical experts and consumers e.g. over the nature of the hazards on which risk assessments should focus and perceptions of insufficient openness about uncertainties in risk assessment. The consumers part of the EU-project, NOFORISK, investigate the disagreement by comparing laypeople...

Hazardous materials in aquatic environments of the Mississippi River Basin. Quarterly project status report, 1 April--30 June 1994

Energy Technology Data Exchange (ETDEWEB)

1994-08-01

This report contains a cluster of twenty separate project reports concerning the fate, environmental transport, and toxicity of hazardous wastes in the Mississippi River Basin. Some of topics investigated involve: biological uptake and metabolism; heavy metal immobilization; biological indicators; toxicity; and mathematical models.

Valuation of potential hazards to ground water from abandoned sites

International Nuclear Information System (INIS)

Kerndorff, H.; Schleyer, R.; Dieter, H.H.

1993-01-01

With a view to obtaining, for the large number of abandoned sites suspected of pollution, necessary information regarding the type and extent of possible ground water contamination with a minimum of effort and cost, a hierarchical investigation strategy was developed and successfully tested in more than 100 cases in Germany. As a decisive advantage, already the well-defined and simple investigation steps ''preliminary prospecting'' and ''screening'' permit to recognize polluted sites posing a hazard to ground water. The more specific and demanding investigation steps ''pollutant analysis'' and ''detailed investigations'' may be carried through if necessary. (orig./BBR). 27 figs., 36 tabs [de

The potential of plants as a system for the development and production of human biologics [version 1; referees: 3 approved

Directory of Open Access Journals (Sweden)

Qiang Chen

2016-05-01

Full Text Available The growing promise of plant-made biologics is highlighted by the success story of ZMapp™ as a potentially life-saving drug during the Ebola outbreak of 2014-2016. Current plant expression platforms offer features beyond the traditional advantages of low cost, high scalability, increased safety, and eukaryotic protein modification. Novel transient expression vectors have been developed that allow the production of vaccines and therapeutics at unprecedented speed to control potential pandemics or bioterrorism attacks. Plant-host engineering provides a method for producing proteins with unique and uniform mammalian post-translational modifications, providing opportunities to develop biologics with increased efficacy relative to their mammalian cell-produced counterparts. Recent demonstrations that plant-made proteins can function as biocontrol agents of foodborne pathogens further exemplify the potential utility of plant-based protein production. However, resolving the technical and regulatory challenges of commercial-scale production, garnering acceptance from large pharmaceutical companies, and obtaining U.S. Food and Drug Administration approval for several major classes of biologics are essential steps to fulfilling the untapped potential of this technology.

Dysfunctional Hematopoietic Stem Cell Biology: Underlying Mechanisms and Potential Therapeutic Strategies

Directory of Open Access Journals (Sweden)

Anja Geiselhart

2012-01-01

Full Text Available Fanconi anemia (FA is the most common inherited bone marrow failure syndrome. FA patients suffer to varying degrees from a heterogeneous range of developmental defects and, in addition, have an increased likelihood of developing cancer. Almost all FA patients develop a severe, progressive bone marrow failure syndrome, which impacts upon the production of all hematopoietic lineages and, hence, is thought to be driven by a defect at the level of the hematopoietic stem cell (HSC. This hypothesis would also correlate with the very high incidence of MDS and AML that is observed in FA patients. In this paper, we discuss the evidence that supports the role of dysfunctional HSC biology in driving the etiology of the disease. Furthermore, we consider the different model systems currently available to study the biology of cells defective in the FA signaling pathway and how they are informative in terms of identifying the physiologic mediators of HSC depletion and dissecting their putative mechanism of action. Finally, we ask whether the insights gained using such disease models can be translated into potential novel therapeutic strategies for the treatment of the hematologic disorders in FA patients.

Therapeutic Potential of Foldamers: From Chemical Biology Tools To Drug Candidates?

Science.gov (United States)

Gopalakrishnan, Ranganath; Frolov, Andrey I; Knerr, Laurent; Drury, William J; Valeur, Eric

2016-11-10

Over the past decade, foldamers have progressively emerged as useful architectures to mimic secondary structures of proteins. Peptidic foldamers, consisting of various amino acid based backbones, have been the most studied from a therapeutic perspective, while polyaromatic foldamers have barely evolved from their nascency and remain perplexing for medicinal chemists due to their poor drug-like nature. Despite these limitations, this compound class may still offer opportunities to study challenging targets or provide chemical biology tools. The potential of foldamer drug candidates reaching the clinic is still a stretch. Nevertheless, advances in the field have demonstrated their potential for the discovery of next generation therapeutics. In this perspective, the current knowledge of foldamers is reviewed in a drug discovery context. Recent advances in the early phases of drug discovery including hit finding, target validation, and optimization and molecular modeling are discussed. In addition, challenges and focus areas are debated and gaps highlighted.

Microbiology and atmospheric processes: biological, physical and chemical characterization of aerosol particles

Directory of Open Access Journals (Sweden)

D. G. Georgakopoulos

2009-04-01

Full Text Available The interest in bioaerosols has traditionally been linked to health hazards for humans, animals and plants. However, several components of bioaerosols exhibit physical properties of great significance for cloud processes, such as ice nucleation and cloud condensation. To gain a better understanding of their influence on climate, it is therefore important to determine the composition, concentration, seasonal fluctuation, regional diversity and evolution of bioaerosols. In this paper, we will review briefly the existing techniques for detection, quantification, physical and chemical analysis of biological particles, attempting to bridge physical, chemical and biological methods for analysis of biological particles and integrate them with aerosol sampling techniques. We will also explore some emerging spectroscopy techniques for bulk and single-particle analysis that have potential for in-situ physical and chemical analysis. Lastly, we will outline open questions and further desired capabilities (e.g., in-situ, sensitive, both broad and selective, on-line, time-resolved, rapid, versatile, cost-effective techniques required prior to comprehensive understanding of chemical and physical characterization of bioaerosols.

Hazardous Waste

Science.gov (United States)

... chemicals can still harm human health and the environment. When you throw these substances away, they become hazardous waste. Some hazardous wastes come from products in our homes. Our garbage can include such hazardous wastes as old batteries, bug spray cans and paint thinner. U.S. residents ...

Projecting community changes in hazard exposure to support long-term risk reduction: A case study of tsunami hazards in the U.S. Pacific Northwest

Science.gov (United States)

Sleeter, Benjamin M.; Wood, Nathan J.; Soulard, Christopher E.; Wilson, Tamara

2017-01-01

Tsunamis have the potential to cause considerable damage to communities along the U.S. Pacific Northwest coastline. As coastal communities expand over time, the potential societal impact of tsunami inundation changes. To understand how community exposure to tsunami hazards may change in coming decades, we projected future development (i.e. urban, residential, and rural), households, and residents over a 50-year period (2011–2061) along the Washington, Oregon, and northern California coasts. We created a spatially explicit, land use/land cover, state-and-transition simulation model to project future developed land use based on historical development trends. We then compared our development projection results to tsunami-hazard zones associated with a Cascadia subduction zone (CSZ) earthquake. Changes in tsunami-hazard exposure by 2061 were estimated for 50 incorporated cities, 7 tribal reservations, and 17 counties relative to current (2011) estimates. Across the region, 2061 population exposure in tsunami-hazard zones was projected to increase by 3880 households and 6940 residents. The top ten communities with highest population exposure to CSZ-related tsunamis in 2011 are projected to remain the areas with the highest population exposure by 2061. The largest net population increases in tsunami-hazard zones were projected in the unincorporated portions of several counties, including Skagit, Coos, and Humboldt. Land-change simulation modeling of projected future development serves as an exploratory tool aimed at helping local governments understand the hazard-exposure implications of community growth and to include this knowledge in risk-reduction planning.

Urban Heat Wave Hazard Assessment

Science.gov (United States)

Quattrochi, D. A.; Jedlovec, G.; Crane, D. L.; Meyer, P. J.; LaFontaine, F.

2016-12-01

Heat waves are one of the largest causes of environmentally-related deaths globally and are likely to become more numerous as a result of climate change. The intensification of heat waves by the urban heat island effect and elevated humidity, combined with urban demographics, are key elements leading to these disasters. Better warning of the potential hazards may help lower risks associated with heat waves. Moderate resolution thermal data from NASA satellites is used to derive high spatial resolution estimates of apparent temperature (heat index) over urban regions. These data, combined with demographic data, are used to produce a daily heat hazard/risk map for selected cities. MODIS data are used to derive daily composite maximum and minimum land surface temperature (LST) fields to represent the amplitude of the diurnal temperature cycle and identify extreme heat days. Compositing routines are used to generate representative daily maximum and minimum LSTs for the urban environment. The limited effect of relative humidity on the apparent temperature (typically 10-15%) allows for the use of modeled moisture fields to convert LST to apparent temperature without loss of spatial variability. The daily max/min apparent temperature fields are used to identify abnormally extreme heat days relative to climatological values in order to produce a heat wave hazard map. Reference to climatological values normalizes the hazard for a particular region (e.g., the impact of an extreme heat day). A heat wave hazard map has been produced for several case study periods and then computed on a quasi-operational basis during the summer of 2016 for Atlanta, GA, Chicago, IL, St. Louis, MO, and Huntsville, AL. A hazard does not become a risk until someone or something is exposed to that hazard at a level that might do harm. Demographic information is used to assess the urban risk associated with the heat wave hazard. Collectively, the heat wave hazard product can warn people in urban

Occupational exposure to potentially infectious biological material in a dental teaching environment.

Science.gov (United States)

Machado-Carvalhais, Helenaura P; Ramos-Jorge, Maria L; Auad, Sheyla M; Martins, Laura H P M; Paiva, Saul M; Pordeus, Isabela A

2008-10-01

The aims of this cross-sectional study were to determine the prevalence of occupational accidents with exposure to biological material among undergraduate students of dentistry and to estimate potential risk factors associated with exposure to blood. Data were collected through a self-administered questionnaire (86.4 percent return rate), which was completed by a sample of 286 undergraduate dental students (mean age 22.4 +/-2.4 years). The students were enrolled in the clinical component of the curriculum, which corresponds to the final six semesters of study. Descriptive, bivariate, simple logistic regression and multiple logistic regression (Forward Stepwise Procedure) analyses were performed. The level of statistical significance was set at 5 percent. Percutaneous and mucous exposures to potentially infectious biological material were reported by 102 individuals (35.6 percent); 26.8 percent reported the occurrence of multiple episodes of exposure. The logistic regression analyses revealed that the incomplete use of individual protection equipment (OR=3.7; 95 percent CI 1.5-9.3), disciplines where surgical procedures are carried out (OR=16.3; 95 percent CI 7.1-37.2), and handling sharp instruments (OR=4.4; 95 percent CI 2.1-9.1), more specifically, hollow-bore needles (OR=6.8; 95 percent CI 2.1-19.0), were independently associated with exposure to blood. Policies of reviewing the procedures during clinical practice are recommended in order to reduce occupational exposure.

Confidence Limits for Hazardous Concentrations Based on Logistically Distributed NOEC Toxicity Data

NARCIS (Netherlands)

Aldenberg T; Slob W

1991-01-01

This paper deals with the calculation of Hazardous Concentrations of toxic substances from small sets of laboratory toxicity data, e.g. NOECs. A procedure due to Van Straalen and Denneman, as adapted from Kooijman (case n=1), in which one seeks a concentration that protects 95% of the biological

Regulatory Activities to the Natural Hazard

International Nuclear Information System (INIS)

Choi, Kangryong; Jung, Raeyoung

2008-01-01

The safety of the Nuclear Power Plants(NPPs) against the natural hazards has been investigated focused on earthquake and tsunami. Since the mass media and general people have high interests on nuclear safety whenever the natural hazards occur, earthquake and tsunami are not only technical safety concern, but also psychological issues in terms of public acceptance of nuclear energy. The Korean peninsula has been considered as a safe zone compared to neighboring countries against natural hazard, but the historical documents which state severely damaged events due to the strong earthquake make US paying careful attention to assure the safety against natural phenomenon. The potential and characteristics of earthquake and tsunami have been examined, and the status of seismic and tsunami safety of the NPPs in Korea is described. the follow-up action after disastrous huge earthquake and tsunami occurred in neighboring countries is summarized as well. The assessment results show that the NPPs in Korea are well designed, constructed and maintained with certain amount of safety margin against natural hazards, and the utility and the regulatory body are continuously doing an effort to enhance the safety with consideration of lessons learned from big events in other countries

Earthquake hazard assessment and small earthquakes

International Nuclear Information System (INIS)

Reiter, L.

1987-01-01

The significance of small earthquakes and their treatment in nuclear power plant seismic hazard assessment is an issue which has received increased attention over the past few years. In probabilistic studies, sensitivity studies showed that the choice of the lower bound magnitude used in hazard calculations can have a larger than expected effect on the calculated hazard. Of particular interest is the fact that some of the difference in seismic hazard calculations between the Lawrence Livermore National Laboratory (LLNL) and Electric Power Research Institute (EPRI) studies can be attributed to this choice. The LLNL study assumed a lower bound magnitude of 3.75 while the EPRI study assumed a lower bound magnitude of 5.0. The magnitudes used were assumed to be body wave magnitudes or their equivalents. In deterministic studies recent ground motion recordings of small to moderate earthquakes at or near nuclear power plants have shown that the high frequencies of design response spectra may be exceeded. These exceedances became important issues in the licensing of the Summer and Perry nuclear power plants. At various times in the past particular concerns have been raised with respect to the hazard and damage potential of small to moderate earthquakes occurring at very shallow depths. In this paper a closer look is taken at these issues. Emphasis is given to the impact of lower bound magnitude on probabilistic hazard calculations and the historical record of damage from small to moderate earthquakes. Limited recommendations are made as to how these issues should be viewed

Ozone dosing alters the biological potential and therapeutic outcomes of plasma rich in growth factors.

Science.gov (United States)

Anitua, E; Zalduendo, M M; Troya, M; Orive, G

2015-04-01

Until now, ozone has been used in a rather empirical way. This in-vitro study investigates, for the first time, whether different ozone treatments of plasma rich in growth factors (PRGF) alter the biological properties and outcomes of this autologous platelet-rich plasma. Human plasma rich in growth factors was treated with ozone using one of the following protocols: a continuous-flow method; or a syringe method in which constant volumes of ozone and PRGF were mixed. In both cases, ozone was added before, during and after the addition of calcium chloride. Three ozone concentrations, of the therapeutic range 20, 40 and 80 μg/mL, were tested. Fibrin clot properties, growth factor content and the proliferative effect on primary osteoblasts and gingival fibroblasts were evaluated. Ozone treatment of PRGF using the continuous flow protocol impaired formation of the fibrin scaffold, drastically reduced the levels of growth factors and significantly decreased the proliferative potential of PRGF on primary osteoblasts and gingival fibroblasts. In contrast, treatment of PRGF with ozone using the syringe method, before, during and after the coagulation process, did not alter the biological outcomes of the autologous therapy. These findings suggest that ozone dose and the way that ozone combines with PRGF may alter the biological potential and therapeutic outcomes of PRGF. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Hazard perception in traffic. [previously knows as: Hazard perception.

NARCIS (Netherlands)

2008-01-01

Hazard perception is an essential part of the driving task. There are clear indications that insufficient skills in perceiving hazards play an important role in the occurrence of crashes, especially those involving novice drivers. Proper hazard perception not only consists of scanning and perceiving

Hazardous waste status of discarded electronic cigarettes

Energy Technology Data Exchange (ETDEWEB)

Krause, Max J.; Townsend, Timothy G., E-mail: ttown@ufl.edu

2015-05-15

Highlights: • Electronic cigarettes were tested using TCLP and WET. • Several electronic cigarette products leached lead at hazardous waste levels. • Lead was the only element that exceeded hazardous waste concentration thresholds. • Nicotine solution may cause hazardous waste classification when discarded unused. - Abstract: The potential for disposable electronic cigarettes (e-cigarettes) to be classified as hazardous waste was investigated. The Toxicity Characteristic Leaching Procedure (TCLP) was performed on 23 disposable e-cigarettes in a preliminary survey of metal leaching. Based on these results, four e-cigarette products were selected for replicate analysis by TCLP and the California Waste Extraction Test (WET). Lead was measured in leachate as high as 50 mg/L by WET and 40 mg/L by TCLP. Regulatory thresholds were exceeded by two of 15 products tested in total. Therefore, some e-cigarettes would be toxicity characteristic (TC) hazardous waste but a majority would not. When disposed in the unused form, e-cigarettes containing nicotine juice would be commercial chemical products (CCP) and would, in the United States (US), be considered a listed hazardous waste (P075). While household waste is exempt from hazardous waste regulation, there are many instances in which such waste would be subject to regulation. Manufactures and retailers with unused or expired e-cigarettes or nicotine juice solution would be required to manage these as hazardous waste upon disposal. Current regulations and policies regarding the availability of nicotine-containing e-cigarettes worldwide were reviewed. Despite their small size, disposable e-cigarettes are consumed and discarded much more quickly than typical electronics, which may become a growing concern for waste managers.

Hazardous waste status of discarded electronic cigarettes

International Nuclear Information System (INIS)

Krause, Max J.; Townsend, Timothy G.

2015-01-01

Highlights: • Electronic cigarettes were tested using TCLP and WET. • Several electronic cigarette products leached lead at hazardous waste levels. • Lead was the only element that exceeded hazardous waste concentration thresholds. • Nicotine solution may cause hazardous waste classification when discarded unused. - Abstract: The potential for disposable electronic cigarettes (e-cigarettes) to be classified as hazardous waste was investigated. The Toxicity Characteristic Leaching Procedure (TCLP) was performed on 23 disposable e-cigarettes in a preliminary survey of metal leaching. Based on these results, four e-cigarette products were selected for replicate analysis by TCLP and the California Waste Extraction Test (WET). Lead was measured in leachate as high as 50 mg/L by WET and 40 mg/L by TCLP. Regulatory thresholds were exceeded by two of 15 products tested in total. Therefore, some e-cigarettes would be toxicity characteristic (TC) hazardous waste but a majority would not. When disposed in the unused form, e-cigarettes containing nicotine juice would be commercial chemical products (CCP) and would, in the United States (US), be considered a listed hazardous waste (P075). While household waste is exempt from hazardous waste regulation, there are many instances in which such waste would be subject to regulation. Manufactures and retailers with unused or expired e-cigarettes or nicotine juice solution would be required to manage these as hazardous waste upon disposal. Current regulations and policies regarding the availability of nicotine-containing e-cigarettes worldwide were reviewed. Despite their small size, disposable e-cigarettes are consumed and discarded much more quickly than typical electronics, which may become a growing concern for waste managers

Hanford B Reactor Building Hazard Assessment Report

International Nuclear Information System (INIS)

Griffin, P. W.

1999-01-01

The 105-B Reactor (hereinafter referred to as B Reactor) is located in the 100 Area of the Hanford Site near Richland, Washington. The B Reactor is one of nine plutonium production reactors that were constructed in the 1940s during the Cold War Era. Construction of the B Reactor began June 7, 1943, and operation began on September 26, 1944. The Environmental Restoration Contractor was requested by RL to provide an assessment/characterization of the B Reactor building to determine and document the hazards that are present and could pose a threat to the environment and/or to individuals touring the building. This report documents the potential hazards, determines the feasibility of mitigating the hazards, and makes recommendations regarding areas where public tour access should not be permitted

Fundamental host range of Leptoypha hospita (Hemiptera: Tingidae), a potential biological control agent of Chinese privet

Science.gov (United States)

Yanzhuo Zhang; James L. Hanula; Scott Horn; Cera Jones; S. Kristine Braman; Jianghua Sun

2016-01-01

Chinese privet, Ligustrum sinense Lour., is an invasive shrub within riparian areas of the southeastern United States. Biological control is considered the most suitable management option for Chinese privet. The potential host range of the lace bug, Leptoypha hospita Drake et...

ASSESSMENT OF EARTHQUAKE HAZARDS ON WASTE LANDFILLS

DEFF Research Database (Denmark)

Zania, Varvara; Tsompanakis, Yiannis; Psarropoulos, Prodromos

Earthquake hazards may arise as a result of: (a) transient ground deformation, which is induced due to seismic wave propagation, and (b) permanent ground deformation, which is caused by abrupt fault dislocation. Since the adequate performance of waste landfills after an earthquake is of outmost...... importance, the current study examines the impact of both types of earthquake hazards by performing efficient finite-element analyses. These took also into account the potential slip displacement development along the geosynthetic interfaces of the composite base liner. At first, the development of permanent...

[Clinical treatment adherence of health care workers and students exposed to potentially infectious biological material].

Science.gov (United States)

Almeida, Maria Cristina Mendes de; Canini, Silvia Rita Marin da Silva; Reis, Renata Karina; Toffano, Silmara Elaine Malaguti; Pereira, Fernanda Maria Vieira; Gir, Elucir

2015-04-01

To assess adherence to clinical appointments by health care workers (HCW) and students who suffered accidents with potentially infectious biological material. A retrospective cross-sectional study that assessed clinical records of accidents involving biological material between 2005 and 2010 in a specialized unit. A total of 461 individuals exposed to biological material were treated, of which 389 (84.4%) were HCWs and 72 (15.6%) students. Of the 461 exposed individuals, 307 (66.6%) attended a follow-up appointment. Individuals who had suffered an accident with a known source patient were 29 times more likely to show up to their scheduled follow-up appointments (OR: 29.98; CI95%: 16.09-55.83). The predictor in both univariate and multivariate analyses for adherence to clinical follow-up appointment was having a known source patient with nonreactive serology for the human immunodeficiency virus and/or hepatitis B and C.

Biological Remediation of Petroleum Contaminants

Science.gov (United States)

Kuhad, Ramesh Chander; Gupta, Rishi

Large volumes of hazardous wastes are generated in the form of oily sludges and contaminated soils during crude oil transportation and processing. Although many physical, chemical and biological treatment technologies are available for petroleum contaminants petroleum contaminants in soil, biological methods have been considered the most cost-effective. Practical biological remediation methods typically involve direct use of the microbes naturally occurring in the contaminated environment and/or cultured indigenous or modified microorganisms. Environmental and nutritional factors, including the properties of the soil, the chemical structure of the hydrocarbon(s), oxygen, water, nutrient availability, pH, temperature, and contaminant bioavailability, can significantly affect the rate and the extent of hydrocarbon biodegradation hydrocarbon biodegradation by microorganisms in contaminated soils. This chapter concisely discusses the major aspects of bioremediation of petroleum contaminants.

Methodology for environmental assessments of oil and hazardous substance spills

Science.gov (United States)

Davis, W. P.; Scott, G. I.; Getter, C. D.; Hayes, M. O.; Gundlach, E. R.

1980-03-01

Scientific assessment of the complex environmental consequences of large spills of oil or other hazardous substances has stimulated development of improved strategies for rapid and valid collection and processing of ecological data. The combination of coastal processes and geological measurements developed by Hayes & Gundlach (1978), together with selected field biological and chemical observations/measurements, provide an ecosystem impact assessment approach which is termed “integrated zonal method of ecological impact assessment.” Ecological assessment of oil and hazardous material spills has been divided into three distinct phases: (1) first-order response studies — conducted at the time of the initial spill event, which gather data to document acute impacts and assist decision-makers in prioritization of cleanup efforts and protection of ecologically sensitive habitats, (2) second-order response studies — conducted two months to one year post-spill, which document any delayed mortality and attempt to identify potential sublethal impacts in sensitive species, and (3) third-order response studies — conducted one to three years post-spill, to document chronic impacts (both lethal and sublethal) to specific indicator species. Data collected during first-order response studies are gathered in a quantitative manner so that the initial assessment may become a baseline for later, more detailed, post-spill scientific efforts. First- and second-order response studies of the “Peck Slip” oil spill in Puerto Rico illustrate the usefulness of this method. The need for contingency planning before a spill has been discussed along with the use of the Vulnerability Index, a method in which coastal environments are classified on a scale of 1 10, based upon their potential susceptibility to oiling. A study of the lower Cook Inlet section of the Alaskan coast illustrates the practical application of this method.

DOE underground storage tank waste remediation chemical processing hazards. Part I: Technology dictionary

International Nuclear Information System (INIS)

DeMuth, S.F.

1996-10-01

This document has been prepared to aid in the development of Regulating guidelines for the Privatization of Hanford underground storage tank waste remediation. The document has been prepared it two parts to facilitate their preparation. Part II is the primary focus of this effort in that it describes the technical basis for established and potential chemical processing hazards associated with Underground Storage Tank (UST) nuclear waste remediation across the DOE complex. The established hazards involve those at Sites for which Safety Analysis Reviews (SARs) have already been prepared. Potential hazards are those involving technologies currently being developed for future applications. Part I of this document outlines the scope of Part II by briefly describing the established and potential technologies. In addition to providing the scope, Part I can be used as a technical introduction and bibliography for Regulatory personnel new to the UST waste remediation, and in particular Privatization effort. Part II of this document is not intended to provide examples of a SAR Hazards Analysis, but rather provide an intelligence gathering source for Regulatory personnel who must eventually evaluate the Privatization SAR Hazards Analysis

Assessment of students’ health condition by indicators of adaptation potential, biological age and bio-energetic reserves of organism

Directory of Open Access Journals (Sweden)

O.V. Martyniuk

2015-06-01

Full Text Available Purpose: to assess students’ health condition by indicators of adaptation potential, biological age and express-assessment. Material: in the research 47 first and second year girl students participated, who belonged to main health group. Results: we distributed the girl students into three groups: 14.89% of them were included in group with “safe” health condition; 34.04% - in group of “third state”; 51.06% were related to group with “ dangerous” health condition. We established that dangerous level was characterized by energy potential of below middle and low level. It is accompanied by accelerated processes of organism’s age destructions and tension of regulation mechanisms. Conclusions: the received results permit to further develop and generalize the data of students’ health’s assessment by indicators of adaptation potentials, biological age and physical health’s condition.

Biological effects of electromagnetic fields

International Nuclear Information System (INIS)

Gabriel, C.

1996-01-01

The effects of electromagnetic (em) fields on biological systems were first observed and exploited well over a century ago. Concern over the possible health hazards of human exposure to such fields developed much later. It is now well known that excessive exposure to em fields may have in undesirable biological consequences. Standards were introduced to determine what constitute an excessive exposure and how to avoid it. Current concern over the issue of hazards stems mainly from recent epidemiological studies of exposed populations and also from the results of laboratory experiments in which whole animals are exposed in vivo or tissue and cell cultures exposed in vitro to low levels of irradiation. The underlying fear is the possibility of a causal relationship between chronic exposure to low field levels and some forms of cancer. So far the evidence does not add up to a firm statement on the matter. At present it is not known how and at what level, if at all, can these exposure be harmful to human health. This state of affair does not provide a basis for incorporating the outcome of such research in exposure standards. This paper will give a brief overview of the research in this field and how it is evaluated for the purpose of producing scientifically based standards. The emphasis will be on the physical, biophysical and biological mechanisms implicated in the interaction between em fields and biological systems. Understanding such mechanisms leads not only to a more accurate evaluation of their health implications but also to their optimal utilization, under controlled conditions, in biomedical applications. (author)

Radiological hazards to uranium miners

International Nuclear Information System (INIS)

1990-05-01

The purpose of the present document is to review and assess the occupational hazards to uranium miners in Canada. Amendments to regulations set the maximum permissible dose to uranium miners at 50 mSv per year. Uranium miners are exposed to radon and thoron progeny, external gamma radiation and long-lived alpha-emitting radionuclides in dust. The best estimate for the lifetime risk of inhaled radon progeny is about 3 x 10 -4 lung cancers per WLM for the average miner, with a range of uncertainty from about 1 -6 x 10 -4 per WLM. This central value is nearly twice as high as that recommended by the ICRP in 1981. The probability of serious biological consequences following exposure to external gamma rays is currently under review but is expected to be in the range of 3 - 6 x 10 -2 Sv -1 . Dosimetric calculations indicate that the stochastic risks per WLM of thoron progeny are about one-third of those for radon progeny. The annual limits on intake of inhaled ore dusts recommended by the ICRP are probably too low by at least a factor of two for the type of ore and dust normally encountered in underground uranium mines in Ontario; this is due in part to the fact that the average diameter of these dusts is five times greater than the value used by the ICRP. Radiological exposures of uranium miners in Canada were reviewed. The biological impact of these exposures were compared with those of conventional accidents on the basis of the years of normal life expectancy that are lost or seriously impaired due to occupational hazards. The objectives in considering all occupational risks are to reduce the total risk from all causes and to use funds spent for health protection as effectively as possible

Accident hazard evaluation and control decisions on forested recreation sites

Science.gov (United States)

Lee A. Paine

1971-01-01

Accident hazard associated with trees on recreation sites is inherently concerned with probabilities. The major factors include the probabilities of mechanical failure and of target impact if failure occurs, the damage potential of the failure, and the target value. Hazard may be evaluated as the product of these factors; i.e., expected loss during the current...