WorldWideScience

Sample records for bioelectricity

  1. Bioelectrical Perchlorate Remediation

    Science.gov (United States)

    Thrash, C.; Achenbach, L. A.; Coates, J. D.

    2007-12-01

    Several bioreactor designs are currently available for the ex-situ biological attenuation of perchlorate- contaminated waters and recently, some of these reactor designs were conditionally approved by the California Department of Health Services for application in the treatment of perchlorate contaminated drinking water. However, all of these systems are dependent on the continual addition of a chemical electron donor to sustain microbial activity and are always subject to biofouling and downstream water quality issues. In addition, residual labile electron donor in the reactor effluent can stimulate microbial growth in water distribution systems and contribute to the formation of potentially toxic trihalomethanes during disinfection by chlorination. As part of our ongoing studies into microbial perchlorate reduction we investigated the ability of dissimilatory perchlorate reducing bacteria (DPRB) to metabolize perchlorate using a negatively charged electrode (cathode) in the working chamber of a bioelectrical reactor (BER) as the primary electron donor. In this instance the DPRB use the electrons on the electrode surface either directly or indirectly in the form of electrolytically produced H2 as a source of reducing equivalents for nitrate and perchlorate reduction. As part of this investigation our fed-batch studies showed that DPRB could use electrons from a graphite cathode poised at -500mV (vs. Ag/AgCl) for the reduction of perchlorate and nitrate. We isolated a novel organism, Dechlorospirillum strain VDY, from the cathode surface after 70 days operation which readily reduced 100 mg.L-1 perchlorate in a mediatorless batch bioelectrical reactor (BER) in 6 days. Continuous up-flow BERs (UFBERs) seeded with active cultures of strain VDY continuously treated waters containing 100 mg.L-1 perchlorate with almost 100% efficiency throughout their operation achieving a non-optimized volumetric loading of 60 mg.L-1 reactor volume.day-1. The same UFBERs also treated

  2. Sugarcane bio ethanol and bioelectricity

    Energy Technology Data Exchange (ETDEWEB)

    Nogueira, Luiz Augusto Horta; Leal, Manoel Regis Lima Verde

    2012-07-01

    This chapter approaches the Brazilian sugar cane production and processing model, sugarcane processing, sugarcane reception, sugarcane preparation and juice extraction, juice treatment, fermentation, distillation, sector efficiencies and future improvement - 2007, 2015 and 2025, present situation (considering the 2007/2008 harvesting season), prospective values for 2015 and for 2025, bioelectricity generation, straw recovery, bagasse availability, energy balance, present situation, perspective for improvements in the GHG mitigation potential, bio ethanol production chain - from field to tank, and surplus electricity generation.

  3. Bioelectric modulation of macrophage polarization

    Science.gov (United States)

    Li, Chunmei; Levin, Michael; Kaplan, David L.

    2016-02-01

    Macrophages play a critical role in regulating wound healing and tissue regeneration by changing their polarization state in response to local microenvironmental stimuli. The native roles of polarized macrophages encompass biomaterials and tissue remodeling needs, yet harnessing or directing the polarization response has been largely absent as a potential strategy to exploit in regenerative medicine to date. Recent data have revealed that specific alteration of cells’ resting potential (Vmem) is a powerful tool to direct proliferation and differentiation in a number of complex tissues, such as limb regeneration, craniofacial patterning and tumorigenesis. In this study, we explored the bioelectric modulation of macrophage polarization by targeting ATP sensitive potassium channels (KATP). Glibenclamide (KATP blocker) and pinacidil (KATP opener) treatment not only affect macrophage polarization, but also influence the phenotype of prepolarized macrophages. Furthermore, modulation of cell membrane electrical properties can fine-tune macrophage plasticity. Glibenclamide decreased the secretion and gene expression of selected M1 markers, while pinacidil augmented M1 markers. More interestingly, glibencalmide promoted macrophage alternative activation by enhancing certain M2 markers during M2 polarization. These findings suggest that control of bioelectric properties of macrophages could offer a promising approach to regulate macrophage phenotype as a useful tool in regenerative medicine.

  4. Bioelectrical impedance analysis--part I

    DEFF Research Database (Denmark)

    Kyle, Ursula G; Bosaeus, Ingvar; De Lorenzo, Antonio D;

    2004-01-01

    The use of bioelectrical impedance analysis (BIA) is widespread both in healthy subjects and patients, but suffers from a lack of standardized method and quality control procedures. BIA allows the determination of the fat-free mass (FFM) and total body water (TBW) in subjects without significant...... of the estimate. The determination of changes in body cell mass (BCM), extra cellular (ECW) and intra cellular water (ICW) requires further research using a valid model that guarantees that ECW changes do not corrupt the ICW. The use of segmental-BIA, multifrequency BIA, or bioelectrical spectroscopy in altered...

  5. The inverse problem of bioelectricity: an evaluation

    NARCIS (Netherlands)

    Oosterom, A. van

    2012-01-01

    This invited paper presents a personal view on the current status of the solution to the inverse problem of bioelectricity. Its focus lies on applications in the field of electrocardiography. The topic discussed is also relevant in other medical domains, such as electroencephalography, electroneurog

  6. Сhanges of brain bioelectric activity by diabetic encephalopathy

    OpenAIRE

    Vitaly P. Omelchenko; Elena A. Timoshenko

    2011-01-01

    This article focuses on the analysis of brain bioelectric activity by diabetic encephalopathy. Paid attention to the establishment of EEG parameters and patients psychological characteristics interrelation.

  7. Bioelectric Applications for Treatment of Melanoma

    International Nuclear Information System (INIS)

    Two new cancer therapies apply bioelectric principles. These methods target tumor structures locally and function by applying millisecond electric fields to deliver plasmid DNA encoding cytokines using electrogene transfer (EGT) or by applying rapid rise-time nanosecond pulsed electric fields (nsPEFs). EGT has been used to locally deliver cytokines such as IL-12 to activate an immune response, resulting in bystander effects. NsPEFs locally induce apoptosis-like effects and affect vascular networks, both promoting tumor demise and restoration of normal vascular homeostasis. EGT with IL-12 is in melanoma clinical trials and nsPEFs are used in models with B16F10 melanoma in vitro and in mice. Applications of bioelectrics, using conventional electroporation and extensions of it, provide effective alternative therapies for melanoma

  8. Bioelectric Applications for Treatment of Melanoma

    Directory of Open Access Journals (Sweden)

    Richard Heller

    2010-09-01

    Full Text Available Two new cancer therapies apply bioelectric principles. These methods target tumor structures locally and function by applying millisecond electric fields to deliver plasmid DNA encoding cytokines using electrogene transfer (EGT or by applying rapid rise-time nanosecond pulsed electric fields (nsPEFs. EGT has been used to locally deliver cytokines such as IL-12 to activate an immune response, resulting in bystander effects. NsPEFs locally induce apoptosis-like effects and affect vascular networks, both promoting tumor demise and restoration of normal vascular homeostasis. EGT with IL-12 is in melanoma clinical trials and nsPEFs are used in models with B16F10 melanoma in vitro and in mice. Applications of bioelectrics, using conventional electroporation and extensions of it, provide effective alternative therapies for melanoma.

  9. Bioelectric Applications for Treatment of Melanoma

    Energy Technology Data Exchange (ETDEWEB)

    Beebe, Stephen J., E-mail: sbeebe@odu.edu; Schoenbach, Karl H.; Heller, Richard [Frank Reidy Research Center for Bioelectrics/Old Dominion University 4211 Monarch Way, Suite 300, Norfolk, Virginia 23508 (United States)

    2010-09-27

    Two new cancer therapies apply bioelectric principles. These methods target tumor structures locally and function by applying millisecond electric fields to deliver plasmid DNA encoding cytokines using electrogene transfer (EGT) or by applying rapid rise-time nanosecond pulsed electric fields (nsPEFs). EGT has been used to locally deliver cytokines such as IL-12 to activate an immune response, resulting in bystander effects. NsPEFs locally induce apoptosis-like effects and affect vascular networks, both promoting tumor demise and restoration of normal vascular homeostasis. EGT with IL-12 is in melanoma clinical trials and nsPEFs are used in models with B16F10 melanoma in vitro and in mice. Applications of bioelectrics, using conventional electroporation and extensions of it, provide effective alternative therapies for melanoma.

  10. Bioelectrical Impedance Assessment of Wound Healing

    OpenAIRE

    Lukaski, Henry C.; Moore, Micheal

    2012-01-01

    Objective assessment of wound healing is fundamental to evaluate therapeutic and nutritional interventions and to identify complications. Despite availability of many techniques to monitor wounds, there is a need for a safe, practical, accurate, and effective method. A new method is localized bioelectrical impedance analysis (BIA) that noninvasively provides information describing cellular changes that occur during healing and signal complications to wound healing. This article describes the ...

  11. ANALYSIS OF INTERNALLY GENERATED NOISE OF BIOELECTRIC AMPLIFIERS

    Institute of Scientific and Technical Information of China (English)

    Mashhour Mustafa; Bani Amer

    2003-01-01

    This paper deals with internally generated noise of bioelectric amplifiers that are usually used for processing of bioelectric events. The main purpose of this paper is to present a procedure for analysis of the effects of internal noise generated by the active circuits and to evaluate the output noise of the author's new designed bioelectric amplifier that caused by internal effects to the amplifier circuit itself in order to compare it with the noise generated by conventional amplifiers. The obtained analysis results of internally generated noise showed that the total output noise of bioelectric active circuits does not increase when some of their resistors have a larger value. This behavior is caused by the different transfer functions for the signal and the respective noise sources associated with these resistors. Moreover, the new designed bioelectric amplifier has an output noise less than that for conventional amplifiers. The obtained analysis results were also experimentally verified and the final conclusions were drawn.

  12. Bioelectrical homeostasis as a component of acupuncture mechanism.

    Science.gov (United States)

    Zukauskas, G; Dapsys, K

    1991-01-01

    Low frequency electrical current and super-high frequency electromagnetic field were applied to acupuncture points of stomach meridian in dogs. The stimulation effect on Bioelectrical potentials of 5 acupuncture points of stomach, spleen, liver, kidney, small intestine meridians and non-acupuncture skin zones was studied in conditions of blocked autonomic ganglia or neuro-muscular junctions of the dog. The influence of ganglioblockading and myorelaxating drugs on Bioelectrical potentials of acupuncture points was also researched. The results are discussed from the neurohumoural and bioelectrical hypotheses points of view. The conclusion that both mechanisms of acupuncture supplement each other is drawn. The principle of bioelectrical homeostasis as a component of acupuncture mechanism is proposed. Bioelectrical homeostasis along with other kinds of homeostasis forms a system of first level homeostats which is united into second level homeostat by the autonomic nervous system. PMID:1685620

  13. Automated experiment for registration of bioelectrical potentials

    Directory of Open Access Journals (Sweden)

    D. V. Chernetchenko

    2013-11-01

    Full Text Available A hardware-software complex automated system of recording bioelectrical potentials, which is based on a USB-device with subsequent processing of signals with PC was developed in this work. We proposed a universal scheme of registration of bioelectrical potentials, which allows one to detect the reaction of biological objects to different stimuli, such as cold, heat, photo- and electrical stimulation, and to different combinations of these stimuli (Motsnyj et al., 2004. They could be applied for deeper understanding of the biological mechanisms of generation of electrical potentials in cells and discovering the accommodation processes of organisms as a whole to these stimuli. The system for registration of bioelectrical potentials consists of hardware and software parts. The software part consists of the client and server sides, which transmit experimental data to the network. The client-side software renders a quantitative analysis and stores the results in a database. An integrated system of registration and biometrical processing was applied for analysis of the electrical responses of maize leaves to heat stimuli. The dynamics of these potentials were studied and a quantitative analysis of the potential level stabilization was made. We found that amplitude relation of responses to the initial response increased and stabilized at the level of 130%. Mathematical models of the plant cell for discovering intracellular mechanisms of biopotentials registration were developed. As a result of modeling, we found that the electrical response of the cells is based on selective conductance of the cell membrane for Н+ and K+ ions. By this way, we show the biophysical relation of plant potentials to intracellular biophysical mechanisms.

  14. Bioelectrical impedance modelling of gentamicin pharmacokinetic parameters.

    Science.gov (United States)

    Zarowitz, B J; Pilla, A M; Peterson, E L

    1989-10-01

    1. Bioelectrical impedance analysis was used to develop descriptive models of gentamicin pharmacokinetic parameters in 30 adult in-patients receiving therapy with gentamicin. 2. Serial blood samples obtained from each subject at steady state were analyzed and used to derive gentamicin pharmacokinetic parameters. 3. Multiple regression equations were developed for clearance, elimination rate constant and volume of distribution at steady state and were all statistically significant at P less than 0.05. 4. Clinical validation of this innovative technique is warranted before clinical use is recommended.

  15. Biohydrogen, bioelectricity and bioalcohols from cellulosic materials

    Energy Technology Data Exchange (ETDEWEB)

    Nissila, M.

    2013-03-01

    The demand for renewable energy is increasing due to increasing energy demand and global warming associated with increasing use of fossil fuels. Renewable energy can be derived from biological production of energy carriers from cellulosic biomass. These biochemical processes include biomass fermentation to hydrogen, methane and alcohols, and bioelectricity production in microbial fuel cells (MFCs). The objective of this study was to investigate the production of different energy carriers (hydrogen, methane, ethanol, butanol, bioelectricity) through biochemical processes. Hydrogen production potential of a hot spring enrichment culture from different sugars was determined, and hydrogen was produced continuously from xylose. Cellulolytic and hydrogenic cultures were enriched on cellulose, cellulosic pulp materials, and on silage at different process conditions. The enrichment cultures were further characterized. The effect of acid pretreatment on hydrogen production from pulp materials was studied and compared to direct pulp fermentation to hydrogen. Electricity and alcohol(s) were simultaneously produced from xylose in MFCs and the exoelectrogenic and alcohologenic enrichment cultures were characterized. In the end, the energy yields obtained from different biochemical processes were determined and compared. In this study, cultures carrying out simultaneous cellulose hydrolysis and hydrogen fermentation were enriched from different sources at different operational conditions. These cultures were successfully utilized for cellulose to hydrogen fermentation in batch systems. Based on these results further research should be conducted on continuous hydrogen production from cellulosic materials.

  16. [Effects of different electrodes on bioelectrical impedance values].

    Science.gov (United States)

    Nakadomo, F; Tanaka, K; Yokoyama, T; Maeda, K

    1990-01-01

    Effects of different electrodes on bioelectrical impedance values measured by the Selco bioelectrical impedance plethysmograph (SIF-881, Japan) were investigated using 8 adult females (age: 35.3 +/- 7.6 yr, Ht: 156.9 +/- 3.8 cm, Wt: 57.1 +/- 9.9 kg, and hydrodensitometrically determined body fat: 29.4 +/- 6.0%). The Lectec MP3000 electrode (Liberty Carton, USA) and the Bipolar electrode (Sanwa, Japan) produced significantly higher impedance values when compared to the Disposable electrode (Adovance, Japan) and the ECG electrode (Nihon Kohden, Japan). The coefficient of variation was significantly lower for the Disposable electrode (0.8%) and the ECG electrode (0.2%) than that for the Lectec MP3000 electrode (2.3%) and the Bipolar electrode (4.9%). In conclusion, the ECG electrode provides higher bioelectrical impedance values with the highest reproducibility in the assessment of human body composition by the bioelectrical impedance plethysmography.

  17. Synthetic electrophysiology: optically controlled oscillators in an engineered bioelectric tissue

    Science.gov (United States)

    McNamara, Harold; Zhang, Hongkang; Werley, Christopher; Cohen, Adam

    Multicellular electrical dynamics underlie crucial physiological functions, but the complexity of natural bioelectricity can obscure the relation of individual components (proteins, cells) to emergent system-level dynamics. Here we introduce optopatch-spiking HEK(OS-HEK) tissue, a minimal synthetic bioelectric tissue with 4 transgenic components that supports optical initiation of propagating electrical waves as well direct optical voltage readout. In conjunction with a home-built inverted microscope capable of patterned illumination, we use this tissue to probe the biophysical attributes of this excitable bioelectric medium, including dispersion relations, curvature-dependent wavefront propagation, electrotonic coupling, and effects of boundaries. We then used chemical patterning to define cellular circuits that support controllable oscillations and which retain memory for more than 2 hours (corresponding to 104 oscillations), constituting a substrate for binary bioelectric data storage. Finally, we use optical patterning of boundary conditions in a physically homogeneous tissue to design dynamically reconfigurable oscillators.

  18. Сhanges of brain bioelectric activity by diabetic encephalopathy

    Directory of Open Access Journals (Sweden)

    Vitaly P. Omelchenko

    2011-05-01

    Full Text Available This article focuses on the analysis of brain bioelectric activity by diabetic encephalopathy. Paid attention to the establishment of EEG parameters and patients psychological characteristics interrelation.

  19. Exploring Instructive Physiological Signaling with the Bioelectric Tissue Simulation Engine

    Science.gov (United States)

    Pietak, Alexis; Levin, Michael

    2016-01-01

    Bioelectric cell properties have been revealed as powerful targets for modulating stem cell function, regenerative response, developmental patterning, and tumor reprograming. Spatio-temporal distributions of endogenous resting potential, ion flows, and electric fields are influenced not only by the genome and external signals but also by their own intrinsic dynamics. Ion channels and electrical synapses (gap junctions) both determine, and are themselves gated by, cellular resting potential. Thus, the origin and progression of bioelectric patterns in multicellular tissues is complex, which hampers the rational control of voltage distributions for biomedical interventions. To improve understanding of these dynamics and facilitate the development of bioelectric pattern control strategies, we developed the BioElectric Tissue Simulation Engine (BETSE), a finite volume method multiphysics simulator, which predicts bioelectric patterns and their spatio-temporal dynamics by modeling ion channel and gap junction activity and tracking changes to the fundamental property of ion concentration. We validate performance of the simulator by matching experimentally obtained data on membrane permeability, ion concentration and resting potential to simulated values, and by demonstrating the expected outcomes for a range of well-known cases, such as predicting the correct transmembrane voltage changes for perturbation of single cell membrane states and environmental ion concentrations, in addition to the development of realistic transepithelial potentials and bioelectric wounding signals. In silico experiments reveal factors influencing transmembrane potential are significantly different in gap junction-networked cell clusters with tight junctions, and identify non-linear feedback mechanisms capable of generating strong, emergent, cluster-wide resting potential gradients. The BETSE platform will enable a deep understanding of local and long-range bioelectrical dynamics in tissues, and

  20. Exploring Instructive Physiological Signaling with the Bioelectric Tissue Simulation Engine.

    Science.gov (United States)

    Pietak, Alexis; Levin, Michael

    2016-01-01

    Bioelectric cell properties have been revealed as powerful targets for modulating stem cell function, regenerative response, developmental patterning, and tumor reprograming. Spatio-temporal distributions of endogenous resting potential, ion flows, and electric fields are influenced not only by the genome and external signals but also by their own intrinsic dynamics. Ion channels and electrical synapses (gap junctions) both determine, and are themselves gated by, cellular resting potential. Thus, the origin and progression of bioelectric patterns in multicellular tissues is complex, which hampers the rational control of voltage distributions for biomedical interventions. To improve understanding of these dynamics and facilitate the development of bioelectric pattern control strategies, we developed the BioElectric Tissue Simulation Engine (BETSE), a finite volume method multiphysics simulator, which predicts bioelectric patterns and their spatio-temporal dynamics by modeling ion channel and gap junction activity and tracking changes to the fundamental property of ion concentration. We validate performance of the simulator by matching experimentally obtained data on membrane permeability, ion concentration and resting potential to simulated values, and by demonstrating the expected outcomes for a range of well-known cases, such as predicting the correct transmembrane voltage changes for perturbation of single cell membrane states and environmental ion concentrations, in addition to the development of realistic transepithelial potentials and bioelectric wounding signals. In silico experiments reveal factors influencing transmembrane potential are significantly different in gap junction-networked cell clusters with tight junctions, and identify non-linear feedback mechanisms capable of generating strong, emergent, cluster-wide resting potential gradients. The BETSE platform will enable a deep understanding of local and long-range bioelectrical dynamics in tissues, and

  1. ANALYSIS OF INTERNALLY GENERATED NOISE OF BIOELECTRIC AMPLIFIERS

    Institute of Scientific and Technical Information of China (English)

    MashhourMustafaBaniAmer

    2003-01-01

    This papenr deals with internally generated noise of bioelectric amplifiers that are usually used for processing of bioelectric events.The main purpose of this paper is to present a procedure for analysis of the effects of internal noise generated by the active circuits and to evaluate the output noise of the author's new designed bioelectric amplifier that caused by internal effects to the amplifier circuit itself in order to compare it with the noise generated by conventional amplifiers.The obtained analysis results of internally generated noise showed that the total output noise of bioelectric active circuits does not increase when some of their resitors have a larger value.This behavior is caused by the different transfer functions for the signal and the respective noise sources associated with these resistors.Moreover,the new designed bioelectric amplifier haws an output noise less than that for conventional amplifiers.The obtained analysis results were also experimentally verified and the final conclusions were drawn.

  2. Bioelectric signaling regulates size in zebrafish fins.

    Directory of Open Access Journals (Sweden)

    Simon Perathoner

    2014-01-01

    Full Text Available The scaling relationship between the size of an appendage or organ and that of the body as a whole is tightly regulated during animal development. If a structure grows at a different rate than the rest of the body, this process is termed allometric growth. The zebrafish another longfin (alf mutant shows allometric growth resulting in proportionally enlarged fins and barbels. We took advantage of this mutant to study the regulation of size in vertebrates. Here, we show that alf mutants carry gain-of-function mutations in kcnk5b, a gene encoding a two-pore domain potassium (K(+ channel. Electrophysiological analysis in Xenopus oocytes reveals that these mutations cause an increase in K(+ conductance of the channel and lead to hyperpolarization of the cell. Further, somatic transgenesis experiments indicate that kcnk5b acts locally within the mesenchyme of fins and barbels to specify appendage size. Finally, we show that the channel requires the ability to conduct K(+ ions to increase the size of these structures. Our results provide evidence for a role of bioelectric signaling through K(+ channels in the regulation of allometric scaling and coordination of growth in the zebrafish.

  3. Enhanced Shewanella biofilm promotes bioelectricity generation.

    Science.gov (United States)

    Liu, Ting; Yu, Yang-Yang; Deng, Xiao-Peng; Ng, Chun Kiat; Cao, Bin; Wang, Jing-Yuan; Rice, Scott A; Kjelleberg, Staffan; Song, Hao

    2015-10-01

    Electroactive biofilms play essential roles in determining the power output of microbial fuel cells (MFCs). To engineer the electroactive biofilm formation of Shewanella oneidensis MR-1, a model exoelectrogen, we herein heterologously overexpressed a c-di-GMP biosynthesis gene ydeH in S. oneidensis MR-1, constructing a mutant strain in which the expression of ydeH is under the control of IPTG-inducible promoter, and a strain in which ydeH is under the control of a constitutive promoter. Such engineered Shewanella strains had significantly enhanced biofilm formation and bioelectricity generation. The MFCs inoculated with these engineered strains accomplished a maximum power density of 167.6 ± 3.6 mW/m(2) , which was ∼ 2.8 times of that achieved by the wild-type MR-1 (61.0 ± 1.9 mW/m(2) ). In addition, the engineered strains in the bioelectrochemical system at poised potential of 0.2 V vs. saturated calomel electrode (SCE) generated a stable current density of 1100 mA/m(2) , ∼ 3.4 times of that by wild-type MR-1 (320 mA/m(2) ). PMID:25899863

  4. Effect of photostimulation on maize leaves’ bioelectrical response

    Directory of Open Access Journals (Sweden)

    M. P. Motsnyj

    2011-06-01

    Full Text Available Dynamics of the maize leaves’ biopotentials evoked by white, blue, green and red light stimuli with an intensity of 90 Lx illumination is analyzed. Qualitative similarity in dynamics of plant’s bioelectrical response to white and colored stimuli is determined. Hyperpolarization levels are quantitatively estimated for each experimental series. Dependence of the total hyperpolarization levels on the photostimulus wave length is detected. Mean amplitude of the hyperpolarization potentials lessens when the wave length decreases: from 57.7 mV under the red light to 27.7 mV under the blue one. Probable forms of bioelectrical response initiation in photostimulated plants are analyzed.

  5. Bioelectric impedance phase angle in breast carcinoma

    Directory of Open Access Journals (Sweden)

    Ruchi Tyagi

    2014-01-01

    Full Text Available Context: Worldwide breast cancer is the most frequently diagnosed life threatening cancer and the leading cause of death in women. Bioelectric impedance analysis (BIA affords an emerging opportunity to assess prognosis because of its ability to non invasively assess cell and plasma membrane structure and function by means of phase angle. Aims: To compare the phase angle between patients of breast cancer and their matched control with the help of BIA. Settings and Design: After taking clearance from ethical committee, a total of 34 female cases of histologically proven infiltrating ductal breast carcinoma were included from the surgery IPD, department of surgery. Equal numbers of the matched controls were recruited from the friends and relatives of cases. Materials and Methods: Bio Electrical Impedance Analyzer (BIA BODY STAT QUAD SCAN 4000 was used to measure resistance (R and reactance (Xc by recording a voltage drop in applied current. Phase angle is the ratio of reactance to resistance and is a measure of cell vitality. Statistical analysis used: Unpaired "t" test was applied. Results: In control group, the phase angle showed a mean of 5.479 whereas in test group, it showed a mean value of 4.726. The P value showed a significant difference (P < 0.0001. The smaller the phase angle values were higher was the tumor, nodes, metastases (TNM staging. The phase angles differed significantly from the healthy age matched control values. Conclusions: This study demonstrated that phase angle is a strong predictor of severity of breast cancer and differed significantly between the two groups.

  6. Carbon fiber enhanced bioelectricity generation in soil microbial fuel cells.

    Science.gov (United States)

    Li, Xiaojing; Wang, Xin; Zhao, Qian; Wan, Lili; Li, Yongtao; Zhou, Qixing

    2016-11-15

    The soil microbial fuel cell (MFC) is a promising biotechnology for the bioelectricity recovery as well as the remediation of organics contaminated soil. However, the electricity production and the remediation efficiency of soil MFC are seriously limited by the tremendous internal resistance of soil. Conductive carbon fiber was mixed with petroleum hydrocarbons contaminated soil and significantly enhanced the performance of soil MFC. The maximum current density, the maximum power density and the accumulated charge output of MFC mixed carbon fiber (MC) were 10, 22 and 16 times as high as those of closed circuit control due to the carbon fiber productively assisted the anode to collect the electron. The internal resistance of MC reduced by 58%, 83% of which owed to the charge transfer resistance, resulting in a high efficiency of electron transfer from soil to anode. The degradation rates of total petroleum hydrocarbons enhanced by 100% and 329% compared to closed and opened circuit controls without the carbon fiber respectively. The effective range of remediation and the bioelectricity recovery was extended from 6 to 20cm with the same area of air-cathode. The mixed carbon fiber apparently enhanced the bioelectricity generation and the remediation efficiency of soil MFC by means of promoting the electron transfer rate from soil to anode. The use of conductively functional materials (e.g. carbon fiber) is very meaningful for the remediation and bioelectricity recovery in the bioelectrochemical remediation.

  7. Carbon fiber enhanced bioelectricity generation in soil microbial fuel cells.

    Science.gov (United States)

    Li, Xiaojing; Wang, Xin; Zhao, Qian; Wan, Lili; Li, Yongtao; Zhou, Qixing

    2016-11-15

    The soil microbial fuel cell (MFC) is a promising biotechnology for the bioelectricity recovery as well as the remediation of organics contaminated soil. However, the electricity production and the remediation efficiency of soil MFC are seriously limited by the tremendous internal resistance of soil. Conductive carbon fiber was mixed with petroleum hydrocarbons contaminated soil and significantly enhanced the performance of soil MFC. The maximum current density, the maximum power density and the accumulated charge output of MFC mixed carbon fiber (MC) were 10, 22 and 16 times as high as those of closed circuit control due to the carbon fiber productively assisted the anode to collect the electron. The internal resistance of MC reduced by 58%, 83% of which owed to the charge transfer resistance, resulting in a high efficiency of electron transfer from soil to anode. The degradation rates of total petroleum hydrocarbons enhanced by 100% and 329% compared to closed and opened circuit controls without the carbon fiber respectively. The effective range of remediation and the bioelectricity recovery was extended from 6 to 20cm with the same area of air-cathode. The mixed carbon fiber apparently enhanced the bioelectricity generation and the remediation efficiency of soil MFC by means of promoting the electron transfer rate from soil to anode. The use of conductively functional materials (e.g. carbon fiber) is very meaningful for the remediation and bioelectricity recovery in the bioelectrochemical remediation. PMID:27162144

  8. Validity of estimating limb muscle volume by bioelectrical impedance.

    Science.gov (United States)

    Miyatani, M; Kanehisa, H; Masuo, Y; Ito, M; Fukunaga, T

    2001-07-01

    The present study aimed to investigate the validity of estimating muscle volume by bioelectrical impedance analysis. Bioelectrical impedance and series cross-sectional images of the forearm, upper arm, lower leg, and thigh on the right side were determined in 22 healthy young adult men using a specially designed bioelectrical impedance acquisition system and magnetic resonance imaging (MRI) method, respectively. The impedance index (L(2)/Z) for every segment, calculated as the ratio of segment length squared to the impedance, was significantly correlated to the muscle volume measured by MRI, with r = 0.902-0.976 (P estimation was 38.4 cm(3) for the forearm, 40.9 cm(3) for the upper arm, 107.2 cm(3) for the lower leg, and 362.3 cm(3) for the thigh. Moreover, isometric torque developed in elbow flexion or extension and knee flexion or extension was significantly correlated to the L(2)/Z values of the upper arm and thigh, respectively, with correlation coefficients of 0.770-0.937 (P knee flexors or extensors. Thus the present study indicates that bioelectrical impedance analysis may be useful to predict the muscle volume and to investigate possible relations between muscle size and strength capability in a limited segment of the upper and lower limbs.

  9. NEUROFEEDBACK INFLUENCE ON CEREBRUM BIOELECTRICAL ACTIVITY IN GYMNASTS-WOMEN

    OpenAIRE

    T. Yu. Strizhkova; Cherapkina, L. P.; O. Yu. Strizhkova

    2013-01-01

    The analysis of electroencephalogram (EEG) of highly skilled gymnasts-women (main group – 49, control group – 39) showed the availability of cerebrum bioelectrical activity features of sportswomen connected with left hemisphere dominance, predominance of theta-rhythm power and lower reaction to eyes closing, also character of neurodynamic changes generated by neurofeedback course depended on ovarian-menstrual cycle phases.

  10. BIOELECTRICAL IMPEDANCE VECTOR ANALYSIS IDENTIFIES SARCOPENIA IN NURSING HOME RESIDENTS

    Science.gov (United States)

    Loss of muscle mass and water shifts between body compartments are contributing factors to frailty in the elderly. The body composition changes are especially pronounced in institutionalized elderly. We investigated the ability of single-frequency bioelectrical impedance analysis (BIA) to identify b...

  11. Bioelectric Control of a 757 Class High Fidelity Aircraft Simulation

    Science.gov (United States)

    Jorgensen, Charles; Wheeler, Kevin; Stepniewski, Slawomir; Norvig, Peter (Technical Monitor)

    2000-01-01

    This paper presents results of a recent experiment in fine grain Electromyographic (EMG) signal recognition, We demonstrate bioelectric flight control of 757 class simulation aircraft landing at San Francisco International Airport. The physical instrumentality of a pilot control stick is not used. A pilot closes a fist in empty air and performs control movements which are captured by a dry electrode array on the arm, analyzed and routed through a flight director permitting full pilot outer loop control of the simulation. A Vision Dome immersive display is used to create a VR world for the aircraft body mechanics and flight changes to pilot movements. Inner loop surfaces and differential aircraft thrust is controlled using a hybrid neural network architecture that combines a damage adaptive controller (Jorgensen 1998, Totah 1998) with a propulsion only based control system (Bull & Kaneshige 1997). Thus the 757 aircraft is not only being flown bioelectrically at the pilot level but also demonstrates damage adaptive neural network control permitting adaptation to severe changes in the physical flight characteristics of the aircraft at the inner loop level. To compensate for accident scenarios, the aircraft uses remaining control surface authority and differential thrust from the engines. To the best of our knowledge this is the first time real time bioelectric fine-grained control, differential thrust based control, and neural network damage adaptive control have been integrated into a single flight demonstration. The paper describes the EMG pattern recognition system and the bioelectric pattern recognition methodology.

  12. NOVEL DESIGN OF A BIOELECTRIC AMPLIFIER WITH MINIMIZED MAGNITUDE AND PHASE ERRORS

    Institute of Scientific and Technical Information of China (English)

    Mashhour Bani Amer; Assistant Professor

    2001-01-01

    A new design of a bioelectric amplifier that has better parameters than conventional designs is presented. The design allows the construction of bioelectric amplifier with improved parameters in terms of common-mode rejection ratio and phase and magnitude errors. The voltage gain is easily adapted to a wide range of biomedical applications. The experimental and simulation results of the designed bioelectric amplifier are also included.

  13. Heterogeneous silicon mesostructures for lipid-supported bioelectric interfaces

    Energy Technology Data Exchange (ETDEWEB)

    Jiang, Yuanwen; Carvalho-de-Souza, João L.; Wong, Raymond C. S.; Luo, Zhiqiang; Isheim, Dieter; Zuo, Xiaobing; Nicholls, Alan W.; Jung, Il Woong; Yue, Jiping; Liu, Di-Jia; Wang, Yucai; De Andrade, Vincent; Xiao, Xianghui; Navrazhnykh, Luizetta; Weiss, Dara E.; Wu, Xiaoyang; Seidman, David N.; Bezanilla, Francisco; Tian, Bozhi

    2016-06-27

    Silicon-based materials have widespread application as biophysical tools and biomedical devices. Here we introduce a biocompatible and degradable mesostructured form of silicon with multi-scale structural and chemical heterogeneities. The material was synthesized using mesoporous silica as a template through a chemical vapour deposition process. It has an amorphous atomic structure, an ordered nanowire-based framework and random submicrometre voids, and shows an average Young’s modulus that is 2–3 orders of magnitude smaller than that of single-crystalline silicon. In addition, we used the heterogeneous silicon mesostructures to design a lipid-bilayer-supported bioelectric interface that is remotely controlled and temporally transient, and that permits non-genetic and subcellular optical modulation of the electrophysiology dynamics in single dorsal root ganglia neurons. Our findings suggest that the biomimetic expansion of silicon into heterogeneous and deformable forms can open up opportunities in extracellular biomaterial or bioelectric systems.

  14. Experimental verification of depolarization effects in bioelectrical impedance measurement.

    Science.gov (United States)

    Chen, Xiaoyan; Lv, Xinqiang; Du, Meng

    2014-01-01

    The electrode polarization effects on bioelectrical impedance measurement at low-frequency cannot be ignored. In this paper, the bioelectrical data of mice livers are measured to specify the polarization effects on the bio-impedance measurement data. We firstly introduce the measurement system and methodology. Using the depolarization method, the corrected results are obtained. Besides, the specific effects of electrode polarization on bio-impedance measurement results are investigated using comparative analysis of the previous and posterior correction results from dielectric spectroscopy, Cole-Cole plot, conductivity and spectroscopy of dissipation tangent. Experimental results show that electrode polarization has a significant influence on the characteristic parameters of mouse liver tissues. To be specific, we see a low-frequency limit resistance R0 increase by 19.29%, a reactance peak XP increase by 8.50%, a low-frequency limit conductivity Kl decrease by 17.65% and a dissipation peak tangent decrease by 160%.

  15. Heterogeneous silicon mesostructures for lipid-supported bioelectric interfaces

    Science.gov (United States)

    Jiang, Yuanwen; Carvalho-de-Souza, João L.; Wong, Raymond C. S.; Luo, Zhiqiang; Isheim, Dieter; Zuo, Xiaobing; Nicholls, Alan W.; Jung, Il Woong; Yue, Jiping; Liu, Di-Jia; Wang, Yucai; de Andrade, Vincent; Xiao, Xianghui; Navrazhnykh, Luizetta; Weiss, Dara E.; Wu, Xiaoyang; Seidman, David N.; Bezanilla, Francisco; Tian, Bozhi

    2016-09-01

    Silicon-based materials have widespread application as biophysical tools and biomedical devices. Here we introduce a biocompatible and degradable mesostructured form of silicon with multi-scale structural and chemical heterogeneities. The material was synthesized using mesoporous silica as a template through a chemical vapour deposition process. It has an amorphous atomic structure, an ordered nanowire-based framework and random submicrometre voids, and shows an average Young's modulus that is 2-3 orders of magnitude smaller than that of single-crystalline silicon. In addition, we used the heterogeneous silicon mesostructures to design a lipid-bilayer-supported bioelectric interface that is remotely controlled and temporally transient, and that permits non-genetic and subcellular optical modulation of the electrophysiology dynamics in single dorsal root ganglia neurons. Our findings suggest that the biomimetic expansion of silicon into heterogeneous and deformable forms can open up opportunities in extracellular biomaterial or bioelectric systems.

  16. NEUROFEEDBACK INFLUENCE ON CEREBRUM BIOELECTRICAL ACTIVITY IN GYMNASTS-WOMEN

    Directory of Open Access Journals (Sweden)

    T. Yu. Strizhkova

    2013-01-01

    Full Text Available The analysis of electroencephalogram (EEG of highly skilled gymnasts-women (main group – 49, control group – 39 showed the availability of cerebrum bioelectrical activity features of sportswomen connected with left hemisphere dominance, predominance of theta-rhythm power and lower reaction to eyes closing, also character of neurodynamic changes generated by neurofeedback course depended on ovarian-menstrual cycle phases.

  17. Bioelectrical Signals as Emerging Biometrics: Issues and Challenges

    OpenAIRE

    Yogendra Narain Singh; Sanjay Kumar Singh; Amit Kumar Ray

    2012-01-01

    This paper presents the effectiveness of bioelectrical signals such as the electrocardiogram (ECG) and the electroencephalogram (EEG) for biometric applications. Studies show that the impulses of cardiac rhythm and electrical activity of the brain recorded in ECG and EEG, respectively; have unique features among individuals, therefore they can be suggested to be used as biometrics for identity verification. The favourable characteristics to use the ECG or EEG signals as biometric include univ...

  18. [Endocrine obesity: bioelectric profiles (biotypes) detected in the body composition].

    Science.gov (United States)

    Miggiano, G A D; Petitti, T

    2004-09-01

    136 patients were selected (16 men and 120 women with non-specific menstrual disturbances) with a BMI (Body Mass Index) between 25 and 45 kg/m2, which were diagnosed with "disendocrinia" (GH deficit, hyperadrenocorticism, hypothyroidsm, hyperandrogenism, menstrual cycle disorders). The proposed approach, based on the visualization of the value distribution of the electric measures in different graphics, is able to immediately explain the bioelectric state of the individual's lean-mass. Subjects with hypothyroidism present, along with their overweight, less bio-conducting mass, with an altered fluid intra/extra-cellular distribution. Patients with hyperadrenocorticism show instead an hyperhydratation of the body mass, especially in the extracellular level. Patients with menstrual disorders (amenorrea, polycystic ovary syndrome, anovulatory cycle etc...) present a lean mass reduction (elevated Rs) and an increase of the intra-cellular compartment (elevated-Xc). Patients with hyper-androgenism (and hirsutism) show a characteristic bioelectric "pattern", with low Rs levels and high Xc levels. Subjects with GH deficit (men and women), has a trend of documenting bioelectric measures with lower lean mass and higher fat-mass. Different electric biotypes seem to characterize the body composition in the several endocrine disorders. PMID:15700636

  19. A Bioassay System Using Bioelectric Signals from Small Fish

    Science.gov (United States)

    Terawaki, Mitsuru; Soh, Zu; Hirano, Akira; Tsuji, Toshio

    Although the quality of tap water is generally examined using chemical assay, this method cannot be used for examination in real time. Against such a background, the technique of fish bioassay has attracted attention as an approach that enables constant monitoring of aquatic contamination. The respiratory rhythms of fish are considered an efficient indicator for the ongoing assessment of water quality, since they are sensitive to chemicals and can be indirectly measured from bioelectric signals generated by breathing. In order to judge aquatic contamination accurately, it is necessary to measure bioelectric signals from fish swimming freely as well as to stably discriminate measured signals, which vary between individuals. However, no bioassay system meeting the above requirements has yet been established. This paper proposes a bioassay system using bioelectric signals generated from small fish in free-swimming conditions. The system records signals using multiple electrodes to cover the extensive measurement range required in a free-swimming environment, and automatically discriminates changes in water quality from signal frequency components. This discrimination is achieved through an ensemble classification method using probability neural networks to solve the problem of differences between individual fish. The paper also reports on the results of related validation experiments, which showed that the proposed system was able to stably discriminate between water conditions before and after bleach exposure.

  20. Bioelectrical signal processing in cardiac and neurological applications and electromyography: physiology, engineering, and noninvasive applications

    Directory of Open Access Journals (Sweden)

    Valentinuzzi Max E

    2007-07-01

    Full Text Available Abstract The present article reviews two recent books dealing with rather closely related subjects; in fact, they tend to complement and supplement reciprocally. Obviously, the electromyogram is a bioelectrical signal that often is mathematically manipulated in different ways to better extract its information. Moreover, its correlation with other bioelectric variables may become necessary.

  1. Bioelectrical signal processing in cardiac and neurological applications and electromyography: physiology, engineering, and noninvasive applications

    OpenAIRE

    Valentinuzzi Max E

    2007-01-01

    Abstract The present article reviews two recent books dealing with rather closely related subjects; in fact, they tend to complement and supplement reciprocally. Obviously, the electromyogram is a bioelectrical signal that often is mathematically manipulated in different ways to better extract its information. Moreover, its correlation with other bioelectric variables may become necessary.

  2. Bioelectricity production from various wastewaters through microbial fuel cell technology

    Directory of Open Access Journals (Sweden)

    Abhilasha S Mathuriya

    2009-12-01

    Full Text Available Microbial fuel cell technology is a new type of renewable and sustainable technology for electricity generation since it recovers energy from renewable materials that can be difficult to dispose of, such as organic wastes and wastewaters. In the present contribution we demonstrated electricity production by beer brewery wastewater, sugar industry wastewater, dairy wastewater, municipal wastewater and paper industry wastewater. Up to 14.92 mA current and 90.23% COD removal was achieved in 10 days of operation. Keywords: Bioelectricity, COD, Microbial Fuel Cells, Wastewater Received: 12 November 2009 / Received in revised form: 30 November 2009, Accepted: 30 November 2009, Published online: 10 March 2010

  3. Bioelectrical Regulation of Cell Cycle and the Planarian Model System

    Science.gov (United States)

    Barghouth, Paul G.; Thiruvalluvan, Manish; Oviedo, Néstor J.

    2015-01-01

    Cell cycle regulation through the manipulation of endogenous membrane potentials offers tremendous opportunities to control cellular processes during tissue repair and cancer formation. However, the molecular mechanisms by which biophysical signals modulate the cell cycle remain underappreciated and poorly understood. Cells in complex organisms generate and maintain a constant voltage gradient across the plasma membrane known as the transmembrane potential. This potential, generated through the combined efforts of various ion transporters, pumps and channels, is known to drive a wide range of cellular processes such as cellular proliferation, migration and tissue regeneration while its deregulation can lead to tumorigenesis. These cellular regulatory events, coordinated by ionic flow, correspond to a new and exciting field termed molecular bioelectricity. We aim to present a brief discussion on the biophysical machinery involving membrane potential and the mechanisms mediating cell cycle progression and cancer transformation. Furthermore, we present the planarian Schmidtea mediterranea as a tractable model system for understanding principles behind molecular bioelectricity at both the cellular and organismal level. PMID:25749155

  4. Optically Controlled Oscillators in an Engineered Bioelectric Tissue

    Science.gov (United States)

    McNamara, Harold M.; Zhang, Hongkang; Werley, Christopher A.; Cohen, Adam E.

    2016-07-01

    Complex electrical dynamics in excitable tissues occur throughout biology, but the roles of individual ion channels can be difficult to determine due to the complex nonlinear interactions in native tissue. Here, we ask whether we can engineer a tissue capable of basic information storage and processing, where all functional components are known and well understood. We develop a cell line with four transgenic components: two to enable collective propagation of electrical waves and two to enable optical perturbation and optical readout of membrane potential. We pattern the cell growth to define simple cellular ring oscillators that run stably for >2 h (˜104 cycles ) and that can store data encoded in the direction of electrical circulation. Using patterned optogenetic stimulation, we probe the biophysical attributes of this synthetic excitable tissue in detail, including dispersion relations, curvature-dependent wave front propagation, electrotonic coupling, and boundary effects. We then apply the biophysical characterization to develop an optically reconfigurable bioelectric oscillator. These results demonstrate the feasibility of engineering bioelectric tissues capable of complex information processing with optical input and output.

  5. A parametric framework for modelling of bioelectrical signals

    CERN Document Server

    Mughal, Yar Muhammad

    2016-01-01

    This book examines non-invasive, electrical-based methods for disease diagnosis and assessment of heart function. In particular, a formalized signal model is proposed since this offers several advantages over methods that rely on measured data alone. By using a formalized representation, the parameters of the signal model can be easily manipulated and/or modified, thus providing mechanisms that allow researchers to reproduce and control such signals. In addition, having such a formalized signal model makes it possible to develop computer tools that can be used for manipulating and understanding how signal changes result from various heart conditions, as well as for generating input signals for experimenting with and evaluating the performance of e.g. signal extraction methods. The work focuses on bioelectrical information, particularly electrical bio-impedance (EBI). Once the EBI has been measured, the corresponding signals have to be modelled for analysis. This requires a structured approach in order to move...

  6. Bioelectrical Impedance Vector Analysis and Muscular Fitness in Healthy Men.

    Science.gov (United States)

    Rodríguez-Rodríguez, Fernando; Cristi-Montero, Carlos; González-Ruíz, Katherine; Correa-Bautista, Jorge Enrique; Ramírez-Vélez, Robinson

    2016-01-01

    Muscle strength can define the general muscular fitness (MF) measurable through hand-grip strength (HG), which is a factor that relates to the health of people of different ages. In this study we evaluated the muscle strength together with a bioimpedance electric analysis in 223 healthy Colombian adult subjects. The bioelectrical impedance vector analysis (BIVA) was conducted to determine the resistance (R), reactance (Xc) and phase angle (PhA). We classified the subjects into three groups (for tertiles), obtaining lower values of R and Xc in subjects with lower HG, plus a high correlation between PhA and HG. An increase in the level of PhA is associated with a high level of MF in a sample of healthy Latin American adult men. The BIVA's parameters and PhA are a potentially effective preventive measure to be integrated into routine screening in the clinical setting. PMID:27384579

  7. Bioelectrical Impedance Vector Analysis and Muscular Fitness in Healthy Men

    Directory of Open Access Journals (Sweden)

    Fernando Rodríguez-Rodríguez

    2016-07-01

    Full Text Available Muscle strength can define the general muscular fitness (MF measurable through hand-grip strength (HG, which is a factor that relates to the health of people of different ages. In this study we evaluated the muscle strength together with a bioimpedance electric analysis in 223 healthy Colombian adult subjects. The bioelectrical impedance vector analysis (BIVA was conducted to determine the resistance (R, reactance (Xc and phase angle (PhA. We classified the subjects into three groups (for tertiles, obtaining lower values of R and Xc in subjects with lower HG, plus a high correlation between PhA and HG. An increase in the level of PhA is associated with a high level of MF in a sample of healthy Latin American adult men. The BIVA’s parameters and PhA are a potentially effective preventive measure to be integrated into routine screening in the clinical setting.

  8. Endogenous bioelectrical networks store non-genetic patterning information during development and regeneration.

    Science.gov (United States)

    Levin, Michael

    2014-06-01

    Pattern formation, as occurs during embryogenesis or regeneration, is the crucial link between genotype and the functions upon which selection operates. Even cancer and aging can be seen as challenges to the continuous physiological processes that orchestrate individual cell activities toward the anatomical needs of an organism. Thus, the origin and maintenance of complex biological shape is a fundamental question for cell, developmental, and evolutionary biology, as well as for biomedicine. It has long been recognized that slow bioelectrical gradients can control cell behaviors and morphogenesis. Here, I review recent molecular data that implicate endogenous spatio-temporal patterns of resting potentials among non-excitable cells as instructive cues in embryogenesis, regeneration, and cancer. Functional data have implicated gradients of resting potential in processes such as limb regeneration, eye induction, craniofacial patterning, and head-tail polarity, as well as in metastatic transformation and tumorigenesis. The genome is tightly linked to bioelectric signaling, via ion channel proteins that shape the gradients, downstream genes whose transcription is regulated by voltage, and transduction machinery that converts changes in bioelectric state to second-messenger cascades. However, the data clearly indicate that bioelectric signaling is an autonomous layer of control not reducible to a biochemical or genetic account of cell state. The real-time dynamics of bioelectric communication among cells are not fully captured by transcriptomic or proteomic analyses, and the necessary-and-sufficient triggers for specific changes in growth and form can be physiological states, while the underlying gene loci are free to diverge. The next steps in this exciting new field include the development of novel conceptual tools for understanding the anatomical semantics encoded in non-neural bioelectrical networks, and of improved biophysical tools for reading and writing

  9. Molecular bioelectricity: how endogenous voltage potentials control cell behavior and instruct pattern regulation in vivo.

    Science.gov (United States)

    Levin, Michael

    2014-12-01

    In addition to biochemical gradients and transcriptional networks, cell behavior is regulated by endogenous bioelectrical cues originating in the activity of ion channels and pumps, operating in a wide variety of cell types. Instructive signals mediated by changes in resting potential control proliferation, differentiation, cell shape, and apoptosis of stem, progenitor, and somatic cells. Of importance, however, cells are regulated not only by their own Vmem but also by the Vmem of their neighbors, forming networks via electrical synapses known as gap junctions. Spatiotemporal changes in Vmem distribution among nonneural somatic tissues regulate pattern formation and serve as signals that trigger limb regeneration, induce eye formation, set polarity of whole-body anatomical axes, and orchestrate craniofacial patterning. New tools for tracking and functionally altering Vmem gradients in vivo have identified novel roles for bioelectrical signaling and revealed the molecular pathways by which Vmem changes are transduced into cascades of downstream gene expression. Because channels and gap junctions are gated posttranslationally, bioelectrical networks have their own characteristic dynamics that do not reduce to molecular profiling of channel expression (although they couple functionally to transcriptional networks). The recent data provide an exciting opportunity to crack the bioelectric code, and learn to program cellular activity at the level of organs, not only cell types. The understanding of how patterning information is encoded in bioelectrical networks, which may require concepts from computational neuroscience, will have transformative implications for embryogenesis, regeneration, cancer, and synthetic bioengineering. PMID:25425556

  10. Comparison of total body water estimates from O-18 and bioelectrical response prediction equations

    Science.gov (United States)

    Barrows, Linda H.; Inners, L. Daniel; Stricklin, Marcella D.; Klein, Peter D.; Wong, William W.; Siconolfi, Steven F.

    1993-01-01

    Identification of an indirect, rapid means to measure total body water (TBW) during space flight may aid in quantifying hydration status and assist in countermeasure development. Bioelectrical response testing and hydrostatic weighing were performed on 27 subjects who ingested O-18, a naturally occurring isotope of oxygen, to measure true TBW. TBW estimates from three bioelectrical response prediction equations and fat-free mass (FFM) were compared to TBW measured from O-18. A repeated measures MANOVA with post-hoc Dunnett's Test indicated a significant (p less than 0.05) difference between TBW estimates from two of the three bioelectrical response prediction equations and O-18. TBW estimates from FFM and the Kushner & Schoeller (1986) equation yielded results that were similar to those given by O-18. Strong correlations existed between each prediction method and O-18; however, standard errors, identified through regression analyses, were higher for the bioelectrical response prediction equations compared to those derived from FFM. These findings suggest (1) the Kushner & Schoeller (1986) equation may provide a valid measure of TBW, (2) other TBW prediction equations need to be identified that have variability similar to that of FFM, and (3) bioelectrical estimates of TBW may prove valuable in quantifying hydration status during space flight.

  11. Microbiology and optimization of hydrogen fermentation and bioelectricity production

    Energy Technology Data Exchange (ETDEWEB)

    Makinen, A.

    2013-11-01

    This work investigated dark fermentative hydrogen (H{sub 2}) and bioelectricity production from carbohydrates. Meso- and thermophilic fermentative and mesophilic exoelectrogenic bacteria were enriched from different natural sources. The H{sub 2} production from different hexoses and pentoses, them main constituents of lignocellulose, was studied in batch assays. H{sub 2} production from xylose was examined in continuous stirred tank reactor (CSTR). Operational parameters for H{sub 2} production were optimized. Bioelectricity production was studied in microbial fuel cells and process parameters were optimized. Dynamics of microbial communities in H{sub 2} and bioelectricity production processes were determined. A novel thermophilic dark fermentative H{sub 2} producing bacterium, Thermovorax subterraneus, was enriched and isolated from geothermal underground mine. T. subterraneus had the optimum growth temperature of 72 deg C and the maximum H{sub 2} yield of 1.4 mol/mol glucose in batch assay. The main soluble fermentative end products of T. subterraneus were acetate and ethanol. Thermophilic dark fermentative mixed culture enriched from hot spring (Hisarlan, Turkey) had the maximum H{sub 2} yield of 1.7 mol/mol glucose. The optimal environmental parameters to maximize H{sub 2} yield were temperature 52 deg C, initial pH 6.5, 40 mg/L Fe{sup 2+}, 4.5 g/L yeast extract and glucose concentration of 4 g/L. Increasing the glucose concentration to 18 g/L increased the maximum H{sub 2} production rate to 56.2 mmol H{sub 2}/h/L. Environmental parameters had a significant effect on metabolic pathways of fermentation. Another hot spring (Hisarkoy, Turkey) enrichment culture was able to ferment different sugars to H{sub 2} favoring pentoses over hexoses. The best H{sub 2} yields in batch assays were obtained from pentoses: xylose, arabinose and ribose yielded 21, 15 and 8 % of the theoretical yield, respectively; whilst on glucose the yield was only 2 % of the theoretical

  12. Is bioelectrical impedance accurate for use in large epidemiological studies?

    Directory of Open Access Journals (Sweden)

    Merchant Anwar T

    2008-09-01

    Full Text Available Abstract Percentage of body fat is strongly associated with the risk of several chronic diseases but its accurate measurement is difficult. Bioelectrical impedance analysis (BIA is a relatively simple, quick and non-invasive technique, to measure body composition. It measures body fat accurately in controlled clinical conditions but its performance in the field is inconsistent. In large epidemiologic studies simpler surrogate techniques such as body mass index (BMI, waist circumference, and waist-hip ratio are frequently used instead of BIA to measure body fatness. We reviewed the rationale, theory, and technique of recently developed systems such as foot (or hand-to-foot BIA measurement, and the elements that could influence its results in large epidemiologic studies. BIA results are influenced by factors such as the environment, ethnicity, phase of menstrual cycle, and underlying medical conditions. We concluded that BIA measurements validated for specific ethnic groups, populations and conditions can accurately measure body fat in those populations, but not others and suggest that for large epdiemiological studies with diverse populations BIA may not be the appropriate choice for body composition measurement unless specific calibration equations are developed for different groups participating in the study.

  13. A comparison of skinfolds and leg-to-leg bioelectrical impedance for the assessment of body composition in children

    Science.gov (United States)

    Goss, Fredric; Robertson, Robert; Williams, Allison; Sward, Kathy; Abt, Kristi; Ladewig, Melissa; Timmer, Jeffrey; Dixon, Curt

    2003-01-01

    Background This field-based investigation examined the congruence between skinfolds and bioelectrical impedance in assessing body composition in children. Methods Subjects were 162 female and 160 male children 10–15 years of age. Skinfold measures obtained at the triceps and medial calf and a leg-to-leg bioelectrical impedance system were used to determine percent fat using child-specific equations. Pearson product moment correlations were performed on the percent fat values obtained using skinfolds and bioelectric impedance for the entire data set. Separate correlations were also conducted on gender and age/gender subsets. Dependent t tests were used to compare the two techniques. Results Percent fat did not differ between skinfolds and bioelectrical impedance for the total subject pool. Bioelectrical impedance overestimated percent fat in girls by 2.6% and underestimated percent fat in boys by 1.7% (p < 0.01). Correlations between skinfolds and bioelectrical impedance ranged from r = 0.51 to r = 0.90. Conclusions Leg-to-leg bioelectrical impedance may be a viable alternative field assessment technique that is comparable to skinfolds. The small differences in percent fat between the two techniques may have limited practical significance in school-based health-fitness settings. PMID:14498990

  14. An introduction to the memristor - a valuable circuit element in bioelectricity and bioimpedance

    Directory of Open Access Journals (Sweden)

    Gorm Krogh Johnsen

    2012-08-01

    Full Text Available The memristor (short for memory resistor is a yet quite unknown circuit element, though equally fundamental as resistors, capacitors, and coils. It was predicted from theory arguments nearly 40 years ago, but not realized as a physical component until recently. The memristor shows many interesting features when describing electrical phenomena, especially at small (molecular or cellular scales and can in particular be useful for bioimpedance and bioelectricity modeling. It can also give us a richer and much improved conceptual understanding of many such phenomena. Up until today the tools available for circuit modeling have been restricted to the three circuit elements (RLC as well as the widely used constant phase element (CPE. However, as one element has been missing in our modeling toolbox, many bioelectrical phenomena may have been described incompletely as they are indeed memristive. Such memristive behavior is not possible to capture within a traditional RLC framework. In this paper we will introduce the memristor and look at potential bioelectrical memristive phenomena. The goal is to explain the new memristor’s properties in a simple manner as well as to highlight its importance and relevance. We conclude that memristors must be included as a readily used building block for bioimpedance and bioelectrical data analysis and modeling.

  15. Bioelectricity-AQA, one of the first MOOC courses in engineering.

    Science.gov (United States)

    Barr, Roger C

    2014-01-01

    Bioelectricity-AQA was one of the first massively open online courses in engineering, having been given the first time via Coursera starting in September, 2012. This report provides some detail on its background, presentation, enrollment, and lessons learned. PMID:25570327

  16. Evidence of potential averaging over the finite surface of a bioelectric surface electrode.

    NARCIS (Netherlands)

    Dijk, J.P. van; Lowery, M.M.; Lapatki, B.; Stegeman, D.F.

    2009-01-01

    Most bioelectric signals are not only functions of time but also exhibit a variation in spatial distribution. Surface EMG signals are often "summarized" by a large electrode. The effect of such an electrode is interpreted as averaging the potential at the surface of the skin beneath the electrode. W

  17. Bioelectricity production from paper industry waste using a microbial fuel cell by Clostridium species

    Directory of Open Access Journals (Sweden)

    Abhilasha S Mathuriya

    2008-12-01

    cellulosic waste was utilized for the bioelectricity production by Clostridium acetobutylicum and Clostridium thermohydrosulfuricum. Keywords: Bacteria, Clostridium acetobutylicum, Clostridium thermohydrosulfuricum, Electricity, Microbial fuel cell. Received: 28 January 2009 / Received in revised form: 5 February 2009, Accepted: 5 February 2009, Published online: 25 February 2009

  18. The Evaluation of Bioelectrical Activity of Pelvic Floor Muscles Depending on Probe Location: A Pilot Study

    Directory of Open Access Journals (Sweden)

    Tomasz Halski

    2013-01-01

    Full Text Available Objectives. The main objective was to determine how the depth of probe placement affects functional and resting bioelectrical activity of the PFM and whether the recorded signal might be dependent on the direction in which the probe is rotated. Participants. The study comprised of healthy, nulliparous women between the ages of 21 and 25. Outcome Measures. Bioelectric activity of the PFM was recorded from four locations of the vagina by surface EMG and vaginal probe. Results. There were no statistically significant differences between the results during functional sEMG activity. During resting sEMG activity, the highest bioelectrical activity of the PFM was observed in the L1 and the lowest in the L4 and a statistically significant difference between the highest and the lowest results of resting sEMG activity was observed (P=0.0043. Conclusion. Different electrodes placement during functional contraction of PFM does not affect the obtained results in sEMG evaluation. In order to diagnose the highest resting activity of PFM the recording plates should be placed toward the anterior vaginal wall and distally from the introitus. However, all of the PFM have similar bioelectrical activity and it seems that these muscles could be treated as a single muscle.

  19. Evaluation of Bioelectrical Impedance Analysis for Identifying Overweight Individuals at Increased Cardiometabolic Risk: A Cross-Sectional Study

    OpenAIRE

    Lamb, Maxine J. E.; Byrne, Christopher D.; Wilson, James F; Wild, Sarah H.

    2014-01-01

    OBJECTIVE: To investigate whether bioelectrical impedance analysis could be used to identify overweight individuals at increased cardiometabolic risk, defined as the presence of metabolic syndrome and/or diabetes.DESIGN AND METHODS: Cross-sectional study of a Scottish population including 1210 women and 788 men. The diagnostic performance of thresholds of percentage body fat measured by bioelectrical impedance analysis to identify people at increased cardiometabolic risk was assessed using re...

  20. Bioelectrical impedance analysis as a laboratory activity: At the interface of physics and the body

    Science.gov (United States)

    Mylott, Elliot; Kutschera, Ellynne; Widenhorn, Ralf

    2014-05-01

    We present a novel laboratory activity on RC circuits aimed at introductory physics students in life-science majors. The activity teaches principles of RC circuits by connecting ac-circuit concepts to bioelectrical impedance analysis (BIA) using a custom-designed educational BIA device. The activity shows how a BIA device works and how current, voltage, and impedance measurements relate to bioelectrical characteristics of the human body. From this, useful observations can be made including body water, fat-free mass, and body fat percentage. The laboratory is engaging to pre-health and life-science students, as well as engineering students who are given the opportunity to observe electrical components and construction of a commonly used biomedical device. Electrical concepts investigated include alternating current, electrical potential, resistance, capacitance, impedance, frequency, phase shift, device design, and the use of such topics in biomedical analysis.

  1. Feasibility of bioelectrical impedance analysis in children with a severe generalized cerebral palsy

    OpenAIRE

    Veugelers, Rebekka; Penning, Corine; van Gulik, Laura; Tibboel, Dick; Evenhuis, Heleen

    2006-01-01

    textabstractObjective: The need is strong for an accurate and easy-to-perform test to evaluate the nutritional state of children who have a severe generalized cerebral palsy, defined as a severe motor handicap and an intellectual disability. For that purpose, we determined the feasibility of bioelectrical impedance analysis (BIA) in these children and evaluated their nutritional state. Methods: BIA recordings were done in 35 children who had a severe generalized cerebral palsy using a single-...

  2. Smartphone-Based Bioelectrical Impedance Analysis Devices for Daily Obesity Management

    OpenAIRE

    Ahyoung Choi; Justin Younghyun Kim; Seongwook Jo; Jae Hwan Jee; Heymsfield, Steven B.; Bhagat, Yusuf A.; Insoo Kim; Jaegeol Cho

    2015-01-01

    Current bioelectric impedance analysis (BIA) systems are often large, cumbersome devices which require strict electrode placement on the user, thus inhibiting mobile capabilities. In this work, we developed a handheld BIA device that measures impedance from multiple frequencies (5 kHz~200 kHz) with four contact electrodes and evaluated the BIA device against standard body composition analysis systems: a dual-energy X-ray absorptiometry (DXA) system (GE Lunar Prodigy, GE Healthcare, Buckingha...

  3. A Role for Bioelectric Effects in the Induction of Bystander Signals by Ionizing Radiation?

    OpenAIRE

    Mothersill, C; Moran, G; McNeill, F.; Gow, M.D.; Denbeigh, J.; Prestwich, W.; Seymour, C. B.

    2007-01-01

    The induction of “bystander effects” i.e. effects in cells which have not received an ionizing radiation track, is now accepted but the mechanisms are not completely clear. Bystander effects following high and low LET radiation exposure are accepted but mechanisms are still not understood. There is some evidence for a physical component to the signal. This paper tests the hypothesis that bioelectric or biomagnetic phenomena are involved. Human immortalized skin keratinocytes and primary expla...

  4. An introduction to the memristor - a valuable circuit element in bioelectricity and bioimpedance

    OpenAIRE

    Gorm Krogh Johnsen

    2012-01-01

    The memristor (short for memory resistor) is a yet quite unknown circuit element, though equally fundamental as resistors, capacitors, and coils. It was predicted from theory arguments nearly 40 years ago, but not realized as a physical component until recently. The memristor shows many interesting features when describing electrical phenomena, especially at small (molecular or cellular) scales and can in particular be useful for bioimpedance and bioelectricity modeling. It can also give us a...

  5. In vitro bioelectric properties of bronchial epithelium from transplanted lungs in recipients with cystic fibrosis.

    OpenAIRE

    Tsang, V. T.; Alton, E. W.; Hodson, M E; Yacoub, M

    1993-01-01

    BACKGROUND--Bronchial epithelial function after heart-lung transplantation (HLT) for cystic fibrosis (CF) may be affected by the original disease as well as other factors such as prolonged organ ischaemic time, the interruption of bronchial arterial and lymphatic supply, infection, rejection, and cyclosporin. In vitro measurement of the bioelectric properties of the bronchial mucosal lining may be an effective means of characterising the mucosal function of the lung allografts in response to ...

  6. [Some problems related to the automatic interpretation of recordings of bioelectric activity in man].

    Science.gov (United States)

    Gaillard, J M

    1975-05-01

    The automatic interpretation of recordings of bioelectric activities in man represents a certain number of difficulties which are discussed more specially insofar as the analysis of automatic polygraphic recordings of sleep. A system of analysis specifically utilising "passe bande" filters has been used to obtain interesting results on many recordings. The interpretation itself is obtained with the help of a small computer coupled to a system of measurement and digitalisation. PMID:1220526

  7. Endogenous Voltage Potentials and the Microenvironment: Bioelectric Signals that Reveal, Induce and Normalize Cancer

    OpenAIRE

    Chernet, Brook; Levin, Michael

    2013-01-01

    Cancer may be a disease of geometry: a misregulation of the field of information that orchestrates individual cells’ activities towards normal anatomy. Recent work identified molecular mechanisms underlying a novel system of developmental control: bioelectric gradients. Endogenous spatio-temporal differences in resting potential of non-neural cells provide instructive cues for cell regulation and complex patterning during embryogenesis and regeneration. It is now appreciated that these cues a...

  8. Molecular bioelectricity: how endogenous voltage potentials control cell behavior and instruct pattern regulation in vivo

    OpenAIRE

    Levin, Michael

    2014-01-01

    In addition to biochemical gradients and transcriptional networks, cell behavior is regulated by endogenous bioelectrical cues originating in the activity of ion channels and pumps, operating in a wide variety of cell types. Instructive signals mediated by changes in resting potential control proliferation, differentiation, cell shape, and apoptosis of stem, progenitor, and somatic cells. Of importance, however, cells are regulated not only by their own V mem but also by the V mem of their ne...

  9. Bioelectrical impedance spectroscopy for the assessment of body fluid volumes of term neonates

    Directory of Open Access Journals (Sweden)

    Ferreira D.M.

    2004-01-01

    Full Text Available The assessment of fluid volume in neonates by a noninvasive, inexpensive, and fast method can contribute significantly to increase the quality of neonatal care. The objective of the present study was to calibrate an acquisition system and software to estimate the bioelectrical impedance parameters obtained by a method of bioelectrical impedance spectroscopy based on step response and to develop specific equations for the neonatal population to determine body fluid compartments. Bioelectric impedance measurements were performed by a laboratory homemade instrument. The volumes were estimated in a clinical study on 30 full-term neonates at four different times during the first month of life. During the first 24 hours of life the total body water, extracellular water and intracellular water were 2.09 ± 0.25, 1.20 ± 0.19, and 0.90 ± 0.25 liters, respectively. By the 48th hour they were 1.87 ± 0.27, 1.08 ± 0.17, and 0.79 ± 0.21 liters, respectively. On the 10th day they were 2.02 ± 0.25, 1.29 ± 0.21, and 0.72 ± 0.14 liters, respectively, and after 1 month they were 2.34 ± 0.27, 1.62 ± 0.20, and 0.72 ± 0.13 liters, respectively. The behavior of the estimated volume was correlated with neonatal body weight changes, leading to a better interpretation of such changes. In conclusion, this study indicates the feasibility of bioelectrical impedance spectroscopy as a method to help fluid administration in intensive care neonatal units, and also contribute to the development of new equations to estimate neonatal body fluid contents.

  10. Brain bioelectrical activity changes in patients with poststroke depression and apathy

    Directory of Open Access Journals (Sweden)

    I. V. Kichuk

    2015-01-01

    Full Text Available Objective: to study the specific features of brain bioelectrical activity in patents with poststroke apathy and depressive disorders.Patients and methods. The investigation enrolled 175 patients (84 men and 91 women with new-onset cerebral stroke at different sites. A total of 107 (61% patients of them were observed to have depressive disorders (n=41 (38% and apathy (n=66 (62% within a year after disease onset. A control group included 68 (39% patients without poststroke affective disorders. The mean age of the study group patients was 66±10 years and that of the control patients was 68±11 years. The severity and magnitude of neurological deficit were evaluated using the U.S. National Institutes of Health Stroke Scale (NIHSS. The patients underwent electroencephalography (EEG, brain computed tomography and magnetic resonance imaging. The investigators used diagnostic and statistical manual of mental disorders (DSM-IV criteria to diagnose depression and the Hamilton depression rating scale (HAM-D and the mini-mental status examination (MMSE to evaluate the mental status. The basic rhythmic power indices in the affected and unaffected hemispheres were calculated, as well as anteroposterior alpha rhythm distribution coefficient and interhemispheric asymmetry coefficient. Results and discussion. The computer EEG analysis was shown to identify the hallmark characteristics of brain bioelectric activity in patients with different types of affective disorders in the acute, early and late recovery periods of stroke. The patients with affective disorders were found to have brain bioelectrical activity changes predominantly in the rapid frequency sub-band on EEG, suggesting midbrain structural dysfunction. In the patients with poststroke depression, depressive disorder scale scores were related to the power of bioelectric activity in the slow and alpha frequency bands manly in the acute stroke period whereas those were correlated with the EEG

  11. Bioelectrical activity of limb muscles during cold shivering of stimulation of the vestibular apparatus

    Science.gov (United States)

    Kuzmina, G. I.

    1980-01-01

    The effects of caloric and electric stimulation of the vestibular receptors on the EMG activity of limb muslces in anesthetized cats during cold induced shivering involved flexor muscles alone. Both types of stimulation suppressed bioelectrical activity more effectively in the ipsilateral muscles. The suppression of shivering activity seems to be due to the increased inhibitory effect of descending labyrinth pathways on the function of flexor motoneurons.

  12. Validity of Bioelectrical Impedance Measurement in Predicting Fat-Free Mass of Chinese Children and Adolescents

    OpenAIRE

    Wang, Lin; Hui, Stanley Sai-chuen; Wong, Stephen Heung-sang

    2014-01-01

    Background The current study aimed to examine the validity of various published bioelectrical impedance analysis (BIA) equations in estimating FFM among Chinese children and adolescents and to develop BIA equations for the estimation of fat-free mass (FFM) appropriate for Chinese children and adolescents. Material/Methods A total of 255 healthy Chinese children and adolescents aged 9 to 19 years old (127 males and 128 females) from Tianjin, China, participated in the BIA measurement at 50 kHz...

  13. Validity of Bioelectrical Impedance Analysis to Estimation Fat-Free Mass in the Army Cadets

    OpenAIRE

    Langer, Raquel D.; Borges, Juliano H.; Pascoa, Mauro A.; Cirolini, Vagner X.; Gil Guerra-Júnior; Ezequiel M. Gonçalves

    2016-01-01

    Background: Bioelectrical Impedance Analysis (BIA) is a fast, practical, non-invasive, and frequently used method for fat-free mass (FFM) estimation. The aims of this study were to validate predictive equations of BIA to FFM estimation in Army cadets and to develop and validate a specific BIA equation for this population. Methods: A total of 396 males, Brazilian Army cadets, aged 17–24 years were included. The study used eight published predictive BIA equations, a specific equation in FFM est...

  14. Bioelectrical Signals and Ion Channels in the Modeling of Multicellular Patterns and Cancer Biophysics

    OpenAIRE

    Javier Cervera; Antonio Alcaraz; Salvador Mafe

    2016-01-01

    Bioelectrical signals and ion channels are central to spatial patterns in cell ensembles, a problem of fundamental interest in positional information and cancer processes. We propose a model for electrically connected cells based on simple biological concepts: i) the membrane potential of a single cell characterizes its electrical state; ii) the long-range electrical coupling of the multicellular ensemble is realized by a network of gap junction channels between neighboring cells; and iii) th...

  15. Models of intracellular mechanisms of plant bioelectrical potentials caused by combined stimulation

    Directory of Open Access Journals (Sweden)

    D. V. Chernetchenko

    2014-10-01

    Full Text Available This paper deals with bioelectrical potentials of the plants recorded during different types of stimuli and combined stimulus as well. All registrations were observed on the leaves of the corn. We used different stimuli, such as cold, heat, photo- and electrical stimulation, and certain combination of this stimuli. Hardware and software system for automated recording of bioelectrical potentials has been successfully used in this work. We proposed the universal pattern of bioelectrical potentials’ recording which allowed to detect the response of the biological object to different stimuli and various combinations of these stimuli. This pattern can be used for the deeper understanding of biological mechanisms of electrical potentials’ generation in cells and discovering of processes of accommodation of whole organisms to these stimuli. Integrated system of recording and biometrical processing was used for analysis of corn leaves electrical responses to the thermal stimuli. The dynamics of these potentials was studied, with the quantitative analysis of the potential level stabilization.We calculated the ratio of amplitude of response potentials to the first response amplitude. Mathematical models of the plant cell were used for studying of intracellular mechanisms of biopotentials gereration. As a result of modeling, we revealed that electrical response of the cells was based on selectiveconductivity of cell membrane for Н+ and Ca2+ ions. Therefore, we showed the biophysical relation of plant potentials to underlying intracellular biophysical mechanisms during thermal and combined stimulation.

  16. Smart Multi-Frequency Bioelectrical Impedance Spectrometer for BIA and BIVA Applications.

    Science.gov (United States)

    Harder, Rene; Diedrich, Andre; Whitfield, Jonathan S; Buchowski, Macie S; Pietsch, John B; Baudenbacher, Franz J

    2016-08-01

    Bioelectrical impedance analysis (BIA) is a noninvasive and commonly used method for the assessment of body composition including body water. We designed a small, portable and wireless multi-frequency impedance spectrometer based on the 12 bit impedance network analyzer AD5933 and a precision wide-band constant current source for tetrapolar whole body impedance measurements. The impedance spectrometer communicates via Bluetooth with mobile devices (smart phone or tablet computer) that provide user interface for patient management and data visualization. The export of patient measurement results into a clinical research database facilitates the aggregation of bioelectrical impedance analysis and biolectrical impedance vector analysis (BIVA) data across multiple subjects and/or studies. The performance of the spectrometer was evaluated using a passive tissue equivalent circuit model as well as a comparison of body composition changes assessed with bioelectrical impedance and dual-energy X-ray absorptiometry (DXA) in healthy volunteers. Our results show an absolute error of 1% for resistance and 5% for reactance measurements in the frequency range of 3 kHz to 150 kHz. A linear regression of BIA and DXA fat mass estimations showed a strong correlation (r(2)=0.985) between measures with a maximum absolute error of 6.5%. The simplicity of BIA measurements, a cost effective design and the simple visual representation of impedance data enables patients to compare and determine body composition during the time course of a specific treatment plan in a clinical or home environment.

  17. Use of bioelectrical impedance analysis to determine body composition changes in HIV-associated wasting.

    Science.gov (United States)

    Klauke, Stephan; Fischer, Harald; Rieger, Armin; Frühauf, Lukas; Staszewski, Schlomo; Althoff, Peter-Henning; Helm, Eilke Brigitte

    2005-04-01

    AIDS wasting syndrome results in loss of lean body mass and body cell mass. This 12-week, open-label study used bioelectrical impedance analysis to measure body composition changes in 24 patients with AIDS wasting syndrome receiving recombinant human growth hormone (r-hGH). The primary endpoint was percentage monthly change in body weight before/after r-hGH. Secondary endpoints included change from baseline in body composition (bioelectrical impedance analysis), isometric strength and CD4+ count. Twenty patients completed the study: r-hGH resulted in mean weight gains (+2.7%, P = 0.146), and significant increases in mean body cell mass (+8.0%, P = 0.0211), lean body mass (+4.8%, P = 0.0373) and water (+5.5%, P r-hGH was generally well tolerated; the most frequent adverse events were fever (7.3%) and diarrhoea (6.3%). Thus, bioelectrical impedance analysis can detect improved body cell mass independent of changes in body weight resulting from r-hGH treatment in patients with AIDS wasting syndrome.

  18. Bioelectrical impedance analysis for the prediction of hot carcass weight in buffalo calf

    Directory of Open Access Journals (Sweden)

    Leopoldo Iannuzzi

    2010-01-01

    Full Text Available Twenty young buffalo male calves were fed ad libitum with a total mix ration and with vitamin-mineral integration for 14 months. Seven days before slaughter, the animals were weighed and bioelectrical impedance measurements were collected in live animals. Physical and chemical characteristics were assessed on the Longissimus dorsi muscle after slaughter. Correlations and regression equations were calculated to determine the possible use of bioelectrical impedance for evaluating hot carcass weight. Bioelectrical impedance analysis at different frequencies, simple correlation and analysis of regression were examined for all the data collected, supporting the possibility of hot carcass weight prediction with equation at multifrequency. The results show that, probably due to the variability in animal live weight, the distribution of the colour parameters was not normally distributed. Moreover, using different frequencies of resistance and reactance, hot carcass weight in buffalo may be predicted with the following equation: Y=98.47–8.84(Rs100KHz+4.41(Rs1000 KHz-116.27(Xc5 KHz+51.04(Xc50 KHz+20.30(Xc100 KHz-33.92(Xc500 KHz+9.01(Xc1000 KHz±ε (Adjusted R Square value of .907 and SE of 5.728 However, further studies are required to improve the technique also in buffalo, after standardization of the method.

  19. Representation of bioelectric current sources using Whitney elements in the finite element method

    Energy Technology Data Exchange (ETDEWEB)

    Tanzer, I Oguz [Laboratory of Biomedical Engineering, PO Box 2200, 02015 HUT and BioMag Laboratory, Medical Engineering Center (Finland); Jaervenpaeae, Seppo [Electromagnetics Laboratory, PO Box 3000, FIN-02015 HUT (Finland); Nenonen, Jukka [Elekta Neuromag Oy, PO Box 68, FIN-00511 Helsinki (Finland); Somersalo, Erkki [Department of Mathematics, PO Box 1100, FIN-02015 HUT (Finland)

    2005-07-07

    Bioelectric current sources of magneto- and electroencephalograms (MEG, EEG) are usually modelled with discrete delta-function type current dipoles, despite the fact that the currents in the brain are naturally continuous throughout the neuronal tissue. In this study, we represent bioelectric current sources in terms of Whitney-type elements in the finite element method (FEM) using a tetrahedral mesh. The aim is to study how well the Whitney elements can reproduce the potential and magnetic field patterns generated by a point current dipole in a homogeneous conducting sphere. The electric potential is solved for a unit sphere model with isotropic conductivity and magnetic fields are calculated for points located on a cap outside the sphere. The computed potential and magnetic field are compared with analytical solutions for a current dipole. Relative difference measures between the FEM and analytical solutions are less than 1%, suggesting that Whitney elements as bioelectric current sources are able to produce the same potential and magnetic field patterns as the point dipole sources.

  20. Smart Multi-Frequency Bioelectrical Impedance Spectrometer for BIA and BIVA Applications.

    Science.gov (United States)

    Harder, Rene; Diedrich, Andre; Whitfield, Jonathan S; Buchowski, Macie S; Pietsch, John B; Baudenbacher, Franz J

    2016-08-01

    Bioelectrical impedance analysis (BIA) is a noninvasive and commonly used method for the assessment of body composition including body water. We designed a small, portable and wireless multi-frequency impedance spectrometer based on the 12 bit impedance network analyzer AD5933 and a precision wide-band constant current source for tetrapolar whole body impedance measurements. The impedance spectrometer communicates via Bluetooth with mobile devices (smart phone or tablet computer) that provide user interface for patient management and data visualization. The export of patient measurement results into a clinical research database facilitates the aggregation of bioelectrical impedance analysis and biolectrical impedance vector analysis (BIVA) data across multiple subjects and/or studies. The performance of the spectrometer was evaluated using a passive tissue equivalent circuit model as well as a comparison of body composition changes assessed with bioelectrical impedance and dual-energy X-ray absorptiometry (DXA) in healthy volunteers. Our results show an absolute error of 1% for resistance and 5% for reactance measurements in the frequency range of 3 kHz to 150 kHz. A linear regression of BIA and DXA fat mass estimations showed a strong correlation (r(2)=0.985) between measures with a maximum absolute error of 6.5%. The simplicity of BIA measurements, a cost effective design and the simple visual representation of impedance data enables patients to compare and determine body composition during the time course of a specific treatment plan in a clinical or home environment. PMID:26863670

  1. Bioelectricity potential in Mato Grosso do Sul, Brazil; O potencial de bioeletricidade no Mato Grosso do Sul

    Energy Technology Data Exchange (ETDEWEB)

    Turdera, Eduardo Mirko Valenzuela [Universidade Federal da Grande Dourados (UFGD), Dourados, MS (Brazil). Faculdade de Ciencias Exatas e Tecnologicas], E-mail: eduardoturdera@ufgd.edu.br

    2009-07-01

    This paper presents the importance of bioelectricity power from renewable source in the power output of Mato Grosso do Sul (MS). The power energy capacity of MS could grow the next years due arrived of more of the thirty mills on medium term. This scenario will be very favorable because MS State will have conditions to meet power domestic market demand and to have significant surplus of electricity to export. Sugar cane crops are expanding and they could propitiate combined heat power (CHP or cogeneration) technology growth, we make an analysis about the share of the bioelectricity availability in MS power capacity installed. Bioelectricity could be good to MS as well as energy and economic aspects. (author)

  2. Body fat measurement by bioelectrical impedance and air displacement plethysmography: a cross-validation study to design bioelectrical impedance equations in Mexican adults

    Directory of Open Access Journals (Sweden)

    Valencia Mauro E

    2007-08-01

    Full Text Available Abstract Background The study of body composition in specific populations by techniques such as bio-impedance analysis (BIA requires validation based on standard reference methods. The aim of this study was to develop and cross-validate a predictive equation for bioelectrical impedance using air displacement plethysmography (ADP as standard method to measure body composition in Mexican adult men and women. Methods This study included 155 male and female subjects from northern Mexico, 20–50 years of age, from low, middle, and upper income levels. Body composition was measured by ADP. Body weight (BW, kg and height (Ht, cm were obtained by standard anthropometric techniques. Resistance, R (ohms and reactance, Xc (ohms were also measured. A random-split method was used to obtain two samples: one was used to derive the equation by the "all possible regressions" procedure and was cross-validated in the other sample to test predicted versus measured values of fat-free mass (FFM. Results and Discussion The final model was: FFM (kg = 0.7374 * (Ht2 /R + 0.1763 * (BW - 0.1773 * (Age + 0.1198 * (Xc - 2.4658. R2 was 0.97; the square root of the mean square error (SRMSE was 1.99 kg, and the pure error (PE was 2.96. There was no difference between FFM predicted by the new equation (48.57 ± 10.9 kg and that measured by ADP (48.43 ± 11.3 kg. The new equation did not differ from the line of identity, had a high R2 and a low SRMSE, and showed no significant bias (0.87 ± 2.84 kg. Conclusion The new bioelectrical impedance equation based on the two-compartment model (2C was accurate, precise, and free of bias. This equation can be used to assess body composition and nutritional status in populations similar in anthropometric and physical characteristics to this sample.

  3. Biohydrogen, biomethane and bioelectricity as crucial components of biorefinery of organic wastes: a review.

    Science.gov (United States)

    Poggi-Varaldo, Héctor M; Munoz-Paez, Karla M; Escamilla-Alvarado, Carlos; Robledo-Narváez, Paula N; Ponce-Noyola, M Teresa; Calva-Calva, Graciano; Ríos-Leal, Elvira; Galíndez-Mayer, Juvencio; Estrada-Vázquez, Carlos; Ortega-Clemente, Alfredo; Rinderknecht-Seijas, Noemí F

    2014-05-01

    Biohydrogen is a sustainable form of energy as it can be produced from organic waste through fermentation processes involving dark fermentation and photofermentation. Very often biohydrogen is included as a part of biorefinery approaches, which reclaim organic wastes that are abundant sources of renewable and low cost substrate that can be efficiently fermented by microorganisms. The aim of this work was to critically assess selected bioenergy alternatives from organic solid waste, such as biohydrogen and bioelectricity, to evaluate their relative advantages and disadvantages in the context of biorefineries, and finally to indicate the trends for future research and development. Biorefining is the sustainable processing of biomass into a spectrum of marketable products, which means: energy, materials, chemicals, food and feed. Dark fermentation of organic wastes could be the beach-head of complete biorefineries that generate biohydrogen as a first step and could significantly influence the future of solid waste management. Series systems show a better efficiency than one-stage process regarding substrate conversion to hydrogen and bioenergy. The dark fermentation also produces fermented by-products (fatty acids and solvents), so there is an opportunity for further combining with other processes that yield more bioenergy. Photoheterotrophic fermentation is one of them: photosynthetic heterotrophs, such as non-sulfur purple bacteria, can thrive on the simple organic substances produced in dark fermentation and light, to give more H2. Effluents from photoheterotrophic fermentation and digestates can be processed in microbial fuel cells for bioelectricity production and methanogenic digestion for methane generation, thus integrating a diverse block of bioenergies. Several digestates from bioenergies could be used for bioproducts generation, such as cellulolytic enzymes and saccharification processes, leading to ethanol fermentation (another bioenergy), thus completing

  4. Biohydrogen, biomethane and bioelectricity as crucial components of biorefinery of organic wastes: a review.

    Science.gov (United States)

    Poggi-Varaldo, Héctor M; Munoz-Paez, Karla M; Escamilla-Alvarado, Carlos; Robledo-Narváez, Paula N; Ponce-Noyola, M Teresa; Calva-Calva, Graciano; Ríos-Leal, Elvira; Galíndez-Mayer, Juvencio; Estrada-Vázquez, Carlos; Ortega-Clemente, Alfredo; Rinderknecht-Seijas, Noemí F

    2014-05-01

    Biohydrogen is a sustainable form of energy as it can be produced from organic waste through fermentation processes involving dark fermentation and photofermentation. Very often biohydrogen is included as a part of biorefinery approaches, which reclaim organic wastes that are abundant sources of renewable and low cost substrate that can be efficiently fermented by microorganisms. The aim of this work was to critically assess selected bioenergy alternatives from organic solid waste, such as biohydrogen and bioelectricity, to evaluate their relative advantages and disadvantages in the context of biorefineries, and finally to indicate the trends for future research and development. Biorefining is the sustainable processing of biomass into a spectrum of marketable products, which means: energy, materials, chemicals, food and feed. Dark fermentation of organic wastes could be the beach-head of complete biorefineries that generate biohydrogen as a first step and could significantly influence the future of solid waste management. Series systems show a better efficiency than one-stage process regarding substrate conversion to hydrogen and bioenergy. The dark fermentation also produces fermented by-products (fatty acids and solvents), so there is an opportunity for further combining with other processes that yield more bioenergy. Photoheterotrophic fermentation is one of them: photosynthetic heterotrophs, such as non-sulfur purple bacteria, can thrive on the simple organic substances produced in dark fermentation and light, to give more H2. Effluents from photoheterotrophic fermentation and digestates can be processed in microbial fuel cells for bioelectricity production and methanogenic digestion for methane generation, thus integrating a diverse block of bioenergies. Several digestates from bioenergies could be used for bioproducts generation, such as cellulolytic enzymes and saccharification processes, leading to ethanol fermentation (another bioenergy), thus completing

  5. Electrical Stimulation: A Panacea for Disease?: DARPA Investigates New Bioelectrical Interfaces for a Range of Disorders.

    Science.gov (United States)

    Grifantini, Kristina

    2016-01-01

    It seems simple: send a small electrical current to a major nerve in the body and stimulate hormones and organs to react in the way you want. New efforts by research teams are doing just that, zapping peripheral nerves attached to major organs in the hopes of addressing problems as diverse as inflammatory bowel disease, chronic pain, and posttraumatic stress disorder. Thanks to the continued advance of smaller and more efficient electronics, researchers are finding new ways to develop implantable bioelectrical devices to treat a wide range of ailments. PMID:27414632

  6. Electrical Stimulation: A Panacea for Disease?: DARPA Investigates New Bioelectrical Interfaces for a Range of Disorders.

    Science.gov (United States)

    Grifantini, Kristina

    2016-01-01

    It seems simple: send a small electrical current to a major nerve in the body and stimulate hormones and organs to react in the way you want. New efforts by research teams are doing just that, zapping peripheral nerves attached to major organs in the hopes of addressing problems as diverse as inflammatory bowel disease, chronic pain, and posttraumatic stress disorder. Thanks to the continued advance of smaller and more efficient electronics, researchers are finding new ways to develop implantable bioelectrical devices to treat a wide range of ailments.

  7. Impact of hemodialysis on dual X-ray absorptiometry, bioelectrical impedance measurements, and anthropometry

    DEFF Research Database (Denmark)

    Abrahamsen, Bo; Hansen, T B; Høgsberg, I M;

    1996-01-01

    Dual X-ray absorptiometry (DXA) performs noninvasive assessment of bone and soft tissue with high precision. However, soft tissue algorithms assume that 73.2% of the lean body mass is water, a potential source of error in fluid retention. We evaluated DXA (model QDR-2000; Hologic Inc, Waltham, MA......), bioelectrical impedance analysis (BIA), and simple anthropometry in 19 patients (9 women and 10 men, mean age 46 y) before and after hemodialysis, removing 0.9-4.3 L (x: 2.8L) of ultrafiltrate. The reduction in fat-free mass (FFM) measured by DXA was highly correlated with the ultrafiltrate, as determined...

  8. A model explaining synchronization of neuron bioelectric frequency under weak alternating low frequency magnetic field

    Energy Technology Data Exchange (ETDEWEB)

    Moral, A. del, E-mail: delmoral@unizar.es [Laboratorio de Magnetismo, Departamento de Física de Materia Condensada and Instituto de Ciencia de Materiales, Universidad de Zaragoza and Consejo Superior de Investigaciones Científicas, 50009 Zaragoza (Spain); Laboratorio de Magnetobiología, Departamento de Anatomía e Histología, Facultad de Medicina, Universidad de Zaragoza, 50009 Zaragoza (Spain); Centro de Tecnología Biomédica, Universidad Politécnica de Madrid, 28223 Madrid (Spain); Azanza, María J., E-mail: mjazanza@unizar.es [Laboratorio de Magnetobiología, Departamento de Anatomía e Histología, Facultad de Medicina, Universidad de Zaragoza, 50009 Zaragoza (Spain); Centro de Tecnología Biomédica, Universidad Politécnica de Madrid, 28223 Madrid (Spain)

    2015-03-01

    A biomagnetic-electrical model is presented that explains rather well the experimentally observed synchronization of the bioelectric potential firing rate (“frequency”), f, of single unit neurons of Helix aspersa mollusc under the application of extremely low frequency (ELF) weak alternating (AC) magnetic fields (MF). The proposed model incorporates to our widely experimentally tested model of superdiamagnetism (SD) and Ca{sup 2+} Coulomb explosion (CE) from lipid (LP) bilayer membrane (SD–CE model), the electrical quadrupolar long range interaction between the bilayer LP membranes of synchronized neuron pairs, not considered before. The quadrupolar interaction is capable of explaining well the observed synchronization. Actual extension of our SD–CE-model shows that the neuron firing frequency field, B, dependence becomes not modified, but the bioelectric frequency is decreased and its spontaneous temperature, T, dependence is modified. A comparison of the model with synchronization experimental results of pair of neurons under weak (B{sub 0}≅0.2–15 mT) AC-MF of frequency f{sub M}=50 Hz is reported. From the deduced size of synchronized LP clusters under B, is suggested the formation of small neuron networks via the membrane lipid correlation. - Highlights: • Neuron pair synchronization under low frequency alternating (AC) magnetic field (MF). • Superdiamagnetism and Ca{sup 2+} Coulomb explosion for AC MF effect in synchronized frequency. • Membrane lipid electrical quadrupolar pair interaction as synchronization mechamism. • Good agreement of model with electrophysiological experiments on mollusc Helix neurons.

  9. [Effect of dosed diet restriction on physiological remodeling and bioelectric properties of bone].

    Science.gov (United States)

    Levashov, M I; Ianko, R V; Chaka, E G; Safonov, S L

    2014-07-01

    The effect of dosed diet restriction on the physiological remodeling and bioelectric properties of bone tissue was studied in 48 male Wistar rats 3- and 18-months of age. The rate of bone tissue apposition was studied by the dynamic histomorphometry method (intravital tetracycline labeling). Electric potentials on the periosteal surface of the freshly isolated femurs were recorded. The magnitude of dielectric loss factor was determined to assess the quality of bone tissue. The control rats received a standard diet. The experimental rats received a limited diet (60 % of the standard mass) for 28 days. The magnitude and rate of the bone tissue apposition on the endosteal and periosteal surface of the tibia were less by 38.4% and 122.7% respectively in experimental rats after dosed diet restriction. Electric potential in the metaphyseal-epiphyseal growth zones of the femur was 29.7% lower, and the dielectric loss factor increased by 15.8%. The bone tissue apposition rate and the electric potential magnitude were increased 10 days after completion of the dosed diet restriction. The magnitude of the dielectric loss factor decreased after returning to the standard diet. Key words: dosed diet restriction, bone, remodelling, bioelectric properties. PMID:25669112

  10. Bioelectrical Signals and Ion Channels in the Modeling of Multicellular Patterns and Cancer Biophysics

    Science.gov (United States)

    Cervera, Javier; Alcaraz, Antonio; Mafe, Salvador

    2016-01-01

    Bioelectrical signals and ion channels are central to spatial patterns in cell ensembles, a problem of fundamental interest in positional information and cancer processes. We propose a model for electrically connected cells based on simple biological concepts: i) the membrane potential of a single cell characterizes its electrical state; ii) the long-range electrical coupling of the multicellular ensemble is realized by a network of gap junction channels between neighboring cells; and iii) the spatial distribution of an external biochemical agent can modify the conductances of the ion channels in a cell membrane and the multicellular electrical state. We focus on electrical effects in small multicellular ensembles, ignoring slow diffusional processes. The spatio-temporal patterns obtained for the local map of cell electric potentials illustrate the normalization of regions with abnormal cell electrical states. The effects of intercellular coupling and blocking of specific channels on the electrical patterns are described. These patterns can regulate the electrically-induced redistribution of charged nanoparticles over small regions of a model tissue. The inclusion of bioelectrical signals provides new insights for the modeling of cancer biophysics because collective multicellular states show electrical coupling mechanisms that are not readily deduced from biochemical descriptions at the individual cell level. PMID:26841954

  11. A novel human-machine interface based on recognition of multi-channel facial bioelectric signals

    International Nuclear Information System (INIS)

    Full text: This paper presents a novel human-machine interface for disabled people to interact with assistive systems for a better quality of life. It is based on multichannel forehead bioelectric signals acquired by placing three pairs of electrodes (physical channels) on the Fron-tails and Temporalis facial muscles. The acquired signals are passes through a parallel filter bank to explore three different sub-bands related to facial electromyogram, electrooculogram and electroencephalogram. The root mean features of the bioelectric signals analyzed within non-overlapping 256 ms windows were extracted. The subtractive fuzzy c-means clustering method (SFCM) was applied to segment the feature space and generate initial fuzzy based Takagi-Sugeno rules. Then, an adaptive neuro-fuzzy inference system is exploited to tune up the premises and consequence parameters of the extracted SFCMs. rules. The average classifier discriminating ratio for eight different facial gestures (smiling, frowning, pulling up left/right lips corner, eye movement to left/right/up/down is between 93.04% and 96.99% according to different combinations and fusions of logical features. Experimental results show that the proposed interface has a high degree of accuracy and robustness for discrimination of 8 fundamental facial gestures. Some potential and further capabilities of our approach in human-machine interfaces are also discussed. (author)

  12. Bioelectrical Signals and Ion Channels in the Modeling of Multicellular Patterns and Cancer Biophysics.

    Science.gov (United States)

    Cervera, Javier; Alcaraz, Antonio; Mafe, Salvador

    2016-01-01

    Bioelectrical signals and ion channels are central to spatial patterns in cell ensembles, a problem of fundamental interest in positional information and cancer processes. We propose a model for electrically connected cells based on simple biological concepts: i) the membrane potential of a single cell characterizes its electrical state; ii) the long-range electrical coupling of the multicellular ensemble is realized by a network of gap junction channels between neighboring cells; and iii) the spatial distribution of an external biochemical agent can modify the conductances of the ion channels in a cell membrane and the multicellular electrical state. We focus on electrical effects in small multicellular ensembles, ignoring slow diffusional processes. The spatio-temporal patterns obtained for the local map of cell electric potentials illustrate the normalization of regions with abnormal cell electrical states. The effects of intercellular coupling and blocking of specific channels on the electrical patterns are described. These patterns can regulate the electrically-induced redistribution of charged nanoparticles over small regions of a model tissue. The inclusion of bioelectrical signals provides new insights for the modeling of cancer biophysics because collective multicellular states show electrical coupling mechanisms that are not readily deduced from biochemical descriptions at the individual cell level. PMID:26841954

  13. Prediction of extracellular water and total body water by multifrequency bio-electrical impedance in a Southeast Asian population

    NARCIS (Netherlands)

    Guricci, S.; Hatriyanti, Y.; Hautvast, J.G.A.J.; Deurenberg, P.

    1999-01-01

    Three different adult Indonesian population groups living on Sumatra (Palembang), Java (Depok) and Sulawesi (Makale) participated in a study on body composition. Body weight, body height and multifrequency bioelectrical impedance (1, 5, 50 and 100 kHz) were measured and in addition total body water

  14. Body Composition Comparison: Bioelectric Impedance Analysis with Dual-Energy X-Ray Absorptiometry in Adult Athletes

    Science.gov (United States)

    Company, Joe; Ball, Stephen

    2010-01-01

    The primary purpose of this study was to investigate the accuracy of the DF50 (ImpediMed Ltd, Eight Mile Plains, Queensland, Australia) bioelectrical impedance analysis device using dual-energy x-ray absorptiometry as the criterion in two groups: endurance athletes and power athletes. The secondary purpose was to develop accurate body fat…

  15. Comparison of Bioelectrical Impedance and Skinfolds with Hydrodensitometry in the Assessment of Body Composition in Healthy Young Adults

    Science.gov (United States)

    Rutherford, W. J.; Diemer, Gary A.; Scott, Eric D.

    2011-01-01

    Bioelectrical impedance analysis (BIA) is a widely used method for estimating body composition, yet issues concerning its validity persist in the literature. The purpose of this study was to validate percentage of body fat (BF) values estimated from BIA and skinfold (SF) with those obtained from hydrodensitometry (HD). Percent BF values measured…

  16. Resting potential, oncogene-induced tumorigenesis, and metastasis: the bioelectric basis of cancer in vivo

    Science.gov (United States)

    Lobikin, Maria; Chernet, Brook; Lobo, Daniel; Levin, Michael

    2012-12-01

    Cancer may result from localized failure of instructive cues that normally orchestrate cell behaviors toward the patterning needs of the organism. Steady-state gradients of transmembrane voltage (Vmem) in non-neural cells are instructive, epigenetic signals that regulate pattern formation during embryogenesis and morphostatic repair. Here, we review molecular data on the role of bioelectric cues in cancer and present new findings in the Xenopus laevis model on how the microenvironment's biophysical properties contribute to cancer in vivo. First, we investigated the melanoma-like phenotype arising from serotonergic signaling by ‘instructor’ cells—a cell population that is able to induce a metastatic phenotype in normal melanocytes. We show that when these instructor cells are depolarized, blood vessel patterning is disrupted in addition to the metastatic phenotype induced in melanocytes. Surprisingly, very few instructor cells need to be depolarized for the hyperpigmentation phenotype to occur; we present a model of antagonistic signaling by serotonin receptors that explains the unusual all-or-none nature of this effect. In addition to the body-wide depolarization-induced metastatic phenotype, we investigated the bioelectrical properties of tumor-like structures induced by canonical oncogenes and cancer-causing compounds. Exposure to carcinogen 4-nitroquinoline 1-oxide (4NQO) induces localized tumors, but has a broad (and variable) effect on the bioelectric properties of the whole body. Tumors induced by oncogenes show aberrantly high sodium content, representing a non-invasive diagnostic modality. Importantly, depolarized transmembrane potential is not only a marker of cancer but is functionally instructive: susceptibility to oncogene-induced tumorigenesis is significantly reduced by forced prior expression of hyperpolarizing ion channels. Importantly, the same effect can be achieved by pharmacological manipulation of endogenous chloride channels, suggesting

  17. The consolidation of the sugar energy sector and the expansion of the bioelectricity; A consolidacao do setor sucroenergetico e a expansao da bioeletricidade

    Energy Technology Data Exchange (ETDEWEB)

    Castro, Nivalde Jose de; Dantas, Guilherme de A.; Brandao, Roberto [Universidade Federal do Rio de Janeiro (GESEL/IE/UFRJ), RJ (Brazil). Inst. de Economica. Grupo de Estudos do Setor Eletrico], Emails: nivalde@ufrj.br, guilhermecrvg@ppe.ufrj.br

    2010-07-01

    The main argument of this paper is that this industrial reorganization of the sugar energy sector is the motive of the viability of technical potential of the bioelectricity generation in the way that allows a greater exploration of scale economies.

  18. Critical factors and their impact on bioelectrical impedance analysis in children

    DEFF Research Database (Denmark)

    Brantlov, Steven; Ward, Leigh C; Jødal, Lars;

    2016-01-01

    to BIA, highlights critical factors that may impact on BIA and identifies areas where there is a need for further research in order to increase the quality of impedance measurements and prediction of body composition in children. Although the results of this review highlights a lack of studies...... in children to provide definitive BIA guidelines, the technique has, however, still proven valuable for body composition assessment in ill and healthy children. To fill the gaps in our knowledge, future studies should focus on methodological issues, particularly with regard to hydration, voiding, clothing......Several guidelines for bioelectrical impedance analysis (BIA) have been prepared for adults, but not for children. For that reason, there is a pressing need to develop a consensus set of guidelines to facilitate standardisation of BIA in this important group. This review provides an introduction...

  19. Validation of bioelectrical-impedance analysis as a measurement of change in body composition in obesity

    International Nuclear Information System (INIS)

    The bioelectrical-impedance-analysis (BIA) method accurately measures body composition in weight-stable subjects. This study validates the use of BIA to measure change in body composition. Twelve obese females underwent weight loss at a mean rate of 1.16 kg/wk. Body composition was measured by deuterium oxide dilution (D2O), BIA, and skinfold anthropometry (SFA) at baseline and at 5% decrements in weight. Highly significant correlations were obtained between D2O and BIA (r = 0.971) and between D2O and SFA (r = 0.932). Overall, BIA predicted change in fat-free mass with greater accuracy (to 0.4 kg) and precision (+/- 1.28 kg) than did anthropometry (to 0.8 kg and +/- 2.58 kg, respectively). We conclude that BIA is a useful clinical method for measuring change in body composition

  20. Programmable Gain Amplifiers with DC Suppression and Low Output Offset for Bioelectric Sensors

    Directory of Open Access Journals (Sweden)

    Alonso Alonso

    2013-09-01

    Full Text Available DC-offset and DC-suppression are key parameters in bioelectric amplifiers. However, specific DC analyses are not often explained. Several factors influence the DC-budget: the programmable gain, the programmable cut-off frequencies for high pass filtering and, the low cut-off values and the capacitor blocking issues involved. A new intermediate stage is proposed to address the DC problem entirely. Two implementations were tested. The stage is composed of a programmable gain amplifier (PGA with DC-rejection and low output offset. Cut-off frequencies are selectable and values from 0.016 to 31.83 Hz were tested, and the capacitor deblocking is embedded in the design. Hence, this PGA delivers most of the required gain with constant low output offset, notwithstanding the gain or cut-off frequency selected.

  1. Validation of bioelectrical-impedance analysis as a measurement of change in body composition in obesity

    Energy Technology Data Exchange (ETDEWEB)

    Kushner, R.F.; Kunigk, A.; Alspaugh, M.; Andronis, P.T.; Leitch, C.A.; Schoeller, D.A. (Univ. of Chicago, IL (USA))

    1990-08-01

    The bioelectrical-impedance-analysis (BIA) method accurately measures body composition in weight-stable subjects. This study validates the use of BIA to measure change in body composition. Twelve obese females underwent weight loss at a mean rate of 1.16 kg/wk. Body composition was measured by deuterium oxide dilution (D2O), BIA, and skinfold anthropometry (SFA) at baseline and at 5% decrements in weight. Highly significant correlations were obtained between D2O and BIA (r = 0.971) and between D2O and SFA (r = 0.932). Overall, BIA predicted change in fat-free mass with greater accuracy (to 0.4 kg) and precision (+/- 1.28 kg) than did anthropometry (to 0.8 kg and +/- 2.58 kg, respectively). We conclude that BIA is a useful clinical method for measuring change in body composition.

  2. Deciphering characteristics of bicyclic aromatics--mediators for reductive decolorization and bioelectricity generation.

    Science.gov (United States)

    Xu, Bin; Chen, Bor-Yann; Hsueh, Chung-Chuan; Qin, Lian-Jie; Chang, Chang-Tang

    2014-07-01

    This first-attempt study quantitatively assessed electron-mediating characteristics of bicyclic aromatics - 1-amino-2-naphthol, 4-amino-1-naphthol (i.e., decolorized intermediates of azo dyes - orange I and II) for color removal and power generation in MFCs. According to cyclic-voltammetric profiles, the presence of reduction and oxidation peak potentials clearly suggested a crucial role of these intermediates as electron-shuttling mediators. Shake-flask cultures also showed that appropriate accumulation of 1A2N, 4A1N apparently enhanced color-removal efficiencies of bacterial decolorization. This study clearly suggested that suitable supplementation of electrochemically active electron shuttle(s) to dye-bearing MFCs is a promising strategy to stimulate reductive decolorization and bioelectricity generation.

  3. Lipid and moisture content modeling of amphidromous Dolly Varden using bioelectrical impedance analysis

    Science.gov (United States)

    Stolarski, J.T.; Margraf, F.J.; Carlson, J.G.; Sutton, T.M.

    2014-01-01

    The physiological well-being or condition of fish is most commonly estimated from aspects of individual morphology. However, these metrics may be only weakly correlated with nutritional reserves stored as lipid, the primary form of accumulated energy in fish. We constructed and evaluated bioelectrical impedance analysis (BIA) models as an alternative method of assessing condition in amphidromous Dolly Varden Salvelinus malma collected from nearshore estuarine and lotic habitats of the Alaskan Arctic. Data on electrical resistance and reactance were collected from the lateral and ventral surfaces of 192 fish, and whole-body percent lipid and moisture content were determined using standard laboratory methods. Significant inverse relationships between temperature and resistance and reactance prompted the standardization of these data to a constant temperature using corrective equations developed herein. No significant differences in resistance or reactance were detected among spawning and nonspawning females after accounting for covariates, suggesting that electrical pathways do not intersect the gonads. Best-fit BIA models incorporating electrical variables calculated from the lateral and ventral surfaces produced the strongest associations between observed and model-predicted estimates of proximate content. These models explained between 6% and 20% more of the variability in laboratory-derived estimates of proximate content than models developed from single-surface BIA data and 32% more than models containing only length and weight data. While additional research is required to address the potential effects of methodological variation, bioelectrical impedance analysis shows promise as a way to provide high-quality, minimally invasive estimates of Dolly Varden lipid or moisture content in the field with only small increases in handling time.

  4. Multi-motion robots control based on bioelectric signals from single-channel dry electrode.

    Science.gov (United States)

    Shen, Hui-Min; Hu, Liang; Lee, Kok-Meng; Fu, Xin

    2015-02-01

    This article presents a multi-motion control system to help severe disabled people operate an auxiliary appliance using neck-up bioelectric signals measured by a single-channel dry electrode on the forehead. The single-channel dry-electrode multi-motion control system exhibits several practical advantages over its conventional counterparts that use multi-channel wet-electrodes; among the challenges is an effective technique to extract bioelectric features for reliable implementation of multi degrees-of-freedom motion control. Using both time and frequency characteristics of the single-channel dry-electrode measurements, motion commands are derived from multiple feature signals associated with concentration demands and different eye-blink actions for use in a two-level control strategy that has been developed to control predefined multi degrees-of-freedom motion trajectories. Test paradigms were designed to pre-calibrate the users' feature signals to statistically account for individual variances. Experimental trials were then carried out on able-bodied and disabled volunteers to validate the universal applicability of the algorithms. The classification success rates for two different eye-blink feature signals were approximately 95% with an average time of 2.4 s for executing a concentration feature signal. The single-channel dry-electrode-based technique has been validated on a 6-degree-of-freedom robot arm demonstrating its significant potentials to help patients suffering severe motor dysfunctions operate a multi-motion auxiliary appliance in everyday living where the ease of use is a priority.

  5. Evaluation of bioelectrical impedance analysis for identifying overweight individuals at increased cardiometabolic risk: a cross-sectional study.

    Directory of Open Access Journals (Sweden)

    Maxine J E Lamb

    Full Text Available OBJECTIVE: To investigate whether bioelectrical impedance analysis could be used to identify overweight individuals at increased cardiometabolic risk, defined as the presence of metabolic syndrome and/or diabetes. DESIGN AND METHODS: Cross-sectional study of a Scottish population including 1210 women and 788 men. The diagnostic performance of thresholds of percentage body fat measured by bioelectrical impedance analysis to identify people at increased cardiometabolic risk was assessed using receiver-operating characteristic curves. Odds ratios for increased cardiometabolic risk in body mass index categories associated with values above compared to below sex-specific percentage body fat thresholds with optimal diagnostic performance were calculated using multivariable logistic regression analyses. The validity of bioelectrical impedance analysis to measure percentage body fat in this population was tested by examining agreement between bioelectrical impedance analysis and dual-energy X-ray absorptiometry in a subgroup of individuals. RESULTS: Participants were aged 16-91 years and the optimal bioelectrical impedance analysis cut-points for percentage body fat for identifying people at increased cardiometabolic risk were 25.9% for men and 37.1% for women. Stratifying by these percentage body fat cut-points, the prevalence of increased cardiometabolic risk was 48% and 38% above the threshold and 24% and 19% below these thresholds for men and women, respectively. By comparison, stratifying by percentage body fat category had little impact on identifying increased cardiometabolic risk in normal weight and obese individuals. Fully adjusted odds ratios of being at increased cardiometabolic risk among overweight people with percentage body fat ≥ 25.9/37.1% compared with percentage body fat <25.9/37.1% as a reference were 1.93 (95% confidence interval: 1.20-3.10 for men and 1.79 (1.10-2.92 for women. CONCLUSION: Percentage body fat measured using

  6. Prediction of fat-free body mass from bioelectrical impedance among 9- to 11-year-old Swedish children

    DEFF Research Database (Denmark)

    Nielsen, Birgit Marie; Dencker, M; Ward, L;

    2007-01-01

    AIM: Predictive equations for estimating body composition from bioelectrical impedance analysis (BIA) among Scandinavian children are lacking. In the present study, equations for estimation of fat-free body mass (FFM) and lean tissue mass (LTM) were developed and cross-validated from BIA using dual......-energy X-ray absorptiometry (DXA) as the reference measurement of body composition. METHODS: The study population consisted of 49 girls and 52 boys aged 9-11 years from Malmö, Sweden. Bioelectrical impedance was measured between hand and foot at 50 kHz. Predictive equations were developed by multiple......-validation revealed a mean RMSE = 0.95 kg FFM and a mean RMSE = 0.96 kg LTM. Prediction of body composition from equations developed in previous literature was mixed when applied to the present cohort of children. CONCLUSIONS: FFM and LTM are predicted with sufficient accuracy at the population level. We recommend...

  7. Exploring characteristics of bioelectricity generation and dye decolorization of mixed and pure bacterial cultures from wine-bearing wastewater treatment.

    Science.gov (United States)

    Han, Jing-Long; Liu, Ying; Chang, Chang-Tang; Chen, Bor-Yann; Chen, Wen-Ming; Xu, Hui-Zhong

    2011-04-01

    This study uncovered microbial characteristics of bioelectricity generation and dye decolorization in single-chamber microbial fuel cells (MFCs) using activated sludge for wine-containing wastewater treatment. Phylogenetic tree analysis on 16S rRNA gene fragments indicated that the predominant strains on anodic biofilm in acclimatized MFCs were Gamma-Proteobacteria Aeromonas punctata NIU-P9, Pseudomonas plecoglossicida NIU-Y3, Pseudomonas koreensis NIU-X8, Acinetobacter junii NIU-Y8, Stenotrophomonas maltophila NIU-X2. Our findings showed that the current production capabilities of these pure strains were only ca. 10% of those of their mother activated sludge, indicating that synergistic interactions among microbes might be the most influential factor to maximize power generation in MFCs. Plus, these electrochemically active strains also performed reductive decolorization of C.I. reactive blue 160, suggesting that bioelectricity generation might be directly associated to azo dye decolorization to deal with electron transfer on anodic biofilm in MFCs.

  8. A Pilot Randomized Trial Evaluating Lymphedema Self-Measurement with Bioelectrical Impedance, Self-Care Adherence, and Health Outcomes

    OpenAIRE

    Ridner, Sheila H.; Shih, Ya-Chen Tina; Doersam, Jennifer K.; Rhoten, Bethany Andrews; Schultze, Benjamin S.; Dietrich, Mary S.

    2014-01-01

    Background: Less than half of breast cancer survivors with lymphedema perform self-care as directed. Effective lymphedema self-care is required to obtain acceptable health outcomes. Self-Regulation Theory suggests that objective self-measurement of physiological conditions is necessary to promote self-regulation/self-care. Bioelectric Impedance Spectroscopy (BIS) represents a potential self-measurement method for arm lymphedema. The purpose of this pilot study was to examine the impact of arm...

  9. Association between muscle hydration measures acquired using bioelectrical impedance spectroscopy and magnetic resonance imaging in healthy and hemodialysis population

    OpenAIRE

    Sawant, Anuradha; House, Andrew A; Chesworth, Bert M.; Connelly, Denise M.; Lindsay, Robert; Gati, Joe; Bartha, Robert; Overend, Tom J.

    2015-01-01

    Abstract Establishing the effect of fluctuating extracellular fluid (ECF) volume on muscle strength in people with end‐stage renal disease (ESRD) on hemodialysis (HD) is essential, as inadequate hydration of the skeletal muscles impacts its strength and endurance. Bioelectrical impedance spectroscopy (BIS) has been a widely used method for estimating ECF volume of a limb or calf segment. Magnetic resonance imaging (MRI)‐acquired transverse relaxation times (T 2) has also been used for estimat...

  10. Reliability of Calf Bioelectrical Impedance Spectroscopy and Magnetic-Resonance-Imaging-Acquired Skeletal Muscle Hydration Measures in Healthy People

    OpenAIRE

    Anuradha Sawant; House, Andrew A; Chesworth, Bert M.; Joseph Gati; Robert Lindsay; Connelly, Denise M.; Robert Bartha; Overend, Tom J.

    2013-01-01

    Purpose. The purpose of this study was to investigate the test-retest reliability, relative variability, and agreement between calf bioelectrical impedance-spectroscopy (cBIS) acquired extracellular fluid (ECF), intracellular fluid (ICF), total water and the ratio of ECF : ICF, magnetic-resonance-imaging (MRI) acquired transverse relaxation times (T2), and apparent diffusion coefficient (ADC) of calf muscles of the same segment in healthy individuals. Methods. Muscle hydration measures were c...

  11. The potential of classic and specific bioelectrical impedance vector analysis for the assessment of sarcopenia and sarcopenic obesity

    OpenAIRE

    Marini E; Buffa R; Saragat B; Coin A; Toffanello ED; Berton L; Manzato E; Sergi G

    2012-01-01

    Elisabetta Marini,1 Roberto Buffa,1 Bruno Saragat,1 Alessandra Coin,2 Elena Debora Toffanello,2 Linda Berton,2 Enzo Manzato,2 Giuseppe Sergi21Department of Environmental and Life Sciences, University of Cagliari, Italy; 2Department of Medicine-DIMED, Geriatrics Section, University of Padua, ItalyPurpose: The aim of this paper is to investigate whether bioelectrical impedance vector analysis (BIVA) can be a suitable technique for the assessment of sarcopenia. We also investigate the potential ...

  12. Dynamic of bioelectric activity back hypothalamus changes in conditions of pyroxan application on the background of stress-reaction developmen

    Directory of Open Access Journals (Sweden)

    T. G. Chaus

    2005-04-01

    Full Text Available The dynamic of changes of capacity of electroencephalogram’s rhythms back hypothalamus at animals of control group and group in stress conditions in parallel with rats who on a background of stress development accepted pyroxan is analyzed. The submitted results have shown influence of a pharmacological preparation pyroxan on bioelectric activity of back hypothalamus in stress conditions that restoration of electric activity under action of this preparation was more shown at 3 weeks of its application.

  13. The efficacy of Bioelectrical Impedance Analysis (BIA) in monitoring body composition changes during treatment of restrictive eating disorder patients

    OpenAIRE

    Saladino, Charles F

    2014-01-01

    Reviews Treating restrictive eating disorder patients is metabolically and psychologically complex. Determining body composition is an important diagnostic and treatment option for these patients, because it ascertains whether the acquisition of body mass during refeeding is metabolically appropriate - ideally an approximate 20/80% - 25/75% fat/lean body mass ratio. The purpose of this paper is to evaluate the efficacy of Bioelectrical Impedance Analysis (BIA) during the treatment period of p...

  14. Prediction of Fat-Free Mass Using Bioelectrical Impedance Analysis in Young Adults from Five Populations of African Origin

    OpenAIRE

    Luke, Amy; Bovet, Pascal; Forrester, Terrence E.; Lambert, Estelle V; Plange-Rhule, Jacob; Dugas, Lara R.; Durazo-Arvizu, Ramon A; Kroff, Jacolene; Richie, Whitney N.; Schoeller, Dale A

    2013-01-01

    Background/Objectives Bio-electrical impedance analysis (BIA) is used in population and clinical studies as a technique for estimating body composition. Because of significant underrepresentation in existing literature, we sought to develop and validate predictive equation(s) for BIA for studies in populations of African origin. Subjects/Methods Among five cohorts of the Modeling the Epidemiologic Transition Study (METS), height, weight, waist circumference and body composition, using isotope...

  15. A high-speed bioelectrical impedance spectroscopy system based on the digital auto-balancing bridge method

    Science.gov (United States)

    Li, Nan; Xu, Hui; Wang, Wei; Zhou, Zhou; Qiao, Guofeng; D-U Li, David

    2013-06-01

    A novel bioelectrical impedance spectroscopy system based on the digital auto-balancing bridge method improved from the conventional analogue auto-balancing method is presented for bioelectrical impedance measurements. The hardware of the proposed system consists of a reference source, a null detector, a variable source, a field programmable gate array, a clock generator, a flash and a USB controller. Software implemented in the field programmable gate array includes three major blocks: clock management, peripheral control and digital signal processing. The principle and realization of the least-mean-squares-based digital auto-balancing algorithm is introduced in detail. The performances of our system were examined by comparing with a commercial impedance analyzer. The results reveal that the proposed system has high speed (less than 3.5 ms per measurement) and high accuracy in the frequency range of 1 kHz-10 MHz. Compared with the commercial instrument based on the traditional analogue auto-balancing method, our system shows advantages in measurement speed, compactness and flexibility, making it suitable for various bioelectrical impedance measurement applications.

  16. A high-speed bioelectrical impedance spectroscopy system based on the digital auto-balancing bridge method

    International Nuclear Information System (INIS)

    A novel bioelectrical impedance spectroscopy system based on the digital auto-balancing bridge method improved from the conventional analogue auto-balancing method is presented for bioelectrical impedance measurements. The hardware of the proposed system consists of a reference source, a null detector, a variable source, a field programmable gate array, a clock generator, a flash and a USB controller. Software implemented in the field programmable gate array includes three major blocks: clock management, peripheral control and digital signal processing. The principle and realization of the least-mean-squares-based digital auto-balancing algorithm is introduced in detail. The performances of our system were examined by comparing with a commercial impedance analyzer. The results reveal that the proposed system has high speed (less than 3.5 ms per measurement) and high accuracy in the frequency range of 1 kHz–10 MHz. Compared with the commercial instrument based on the traditional analogue auto-balancing method, our system shows advantages in measurement speed, compactness and flexibility, making it suitable for various bioelectrical impedance measurement applications. (paper)

  17. The potential of classic and specific bioelectrical impedance vector analysis for the assessment of sarcopenia and sarcopenic obesity

    Directory of Open Access Journals (Sweden)

    Marini E

    2012-12-01

    Full Text Available Elisabetta Marini,1 Roberto Buffa,1 Bruno Saragat,1 Alessandra Coin,2 Elena Debora Toffanello,2 Linda Berton,2 Enzo Manzato,2 Giuseppe Sergi21Department of Environmental and Life Sciences, University of Cagliari, Italy; 2Department of Medicine-DIMED, Geriatrics Section, University of Padua, ItalyPurpose: The aim of this paper is to investigate whether bioelectrical impedance vector analysis (BIVA can be a suitable technique for the assessment of sarcopenia. We also investigate the potential use of specific BIVA as an indicator of sarcopenic obesity.Subjects and methods: The sample comprised 207 free-living elderly individuals of both sexes, aged 65 to 93 years. Anthropometric and bioelectrical measurements were taken according to standard criteria. The “classic” and “specific” BIVA procedures, which respectively correct bioelectrical values for body height and body geometry, were used. Dual energy X-ray absorptiometry (DXA was used as the reference method for identifying sarcopenic and obese sarcopenic individuals. Bioelectrical and DXA values were compared using Student’s t-test and Hotelling’s T2 test, as well as Pearson’s correlation coefficient.Results: According to classic BIVA, sarcopenic individuals of both sexes showed higher values of resistance/height (R/H; p < 0.01 and impedance/height (Z/H; p < 0.01, and a lower phase angle (p < 0.01. Similarly, specific BIVA showed significant differences between sarcopenic and nonsarcopenic individuals (men: T2 = 15.7, p < 0.01; women: T2 = 10.7, p < 0.01, with the sarcopenic groups showing a lower specific reactance and phase angle. Phase angle was positively correlated with the skeletal muscle mass index (men: r = 0.52, p < 0.01; women: r = 0.31, p < 0.01. Specific BIVA also recognized bioelectrical differences between sarcopenic and sarcopenic obese men (T2 = 13.4, p < 0.01, mainly due to the higher values of specific R in sarcopenic obese individuals.Conclusion: BIVA detected

  18. Tissue electrical properties measured by bioelectrical impedance analysis among healthy and sportsmen population

    Science.gov (United States)

    Kapica, Dominik; Warchulińska, Joanna; Jakubiak, Monika; Teter, Mariusz; Mlak, Radosław; Hałabiś, Magdalena; Wójcik, Waldemar; Małecka-Massalska, Teresa

    2015-09-01

    Introduction: Bioelectrical impedance analysis (BIA) is a useful tool to asses human body composition and nutrition status; multi-frequency BIA has a higher accuracy than single-frequency BIA. In our study a difference of impedance values (Z) at 5, 100 and 200 kHz and Z200/Z5 index between professional athletes and control group were determined. Methods: In this research 105 people were tested, divided into control group (72 people: 35 males and 37 females) and professional athletes (33 people: 16 males and 17 females). Impedance was measured at three frequency values - 5, 100 and 200 kHz; with received values the Z200/Z5 index was calculated. Results: In most compared subgroups impedance values showed significantly lower values in athletes than in control group (5 kHz - males: p=0.136, females: p=0.001, 100 kHz - males: p=0.039, females: pnutrition status and general health condition of athletes than in control group.

  19. Bioelectrical impedance vector analysis for evaluating zinc supplementation in prepubertal and healthy children

    Directory of Open Access Journals (Sweden)

    Márcia Marília Gomes Dantas

    2015-09-01

    Full Text Available Background: The prevalence of abnormal nutritional status has increased in children and adolescents. Nutritional assessment is important for monitoring the health and nutritional status. Bioelectrical impedance vector analysis (BIVA combines changes in tissue hydration and structure and body composition that can be assessed. Objectives: The objective of this study was to use BIVA to evaluate nutritional status in 60 prepubertal children, aged between 8 and 9 years, supplemented with zinc, to detect possible changes in body composition. Design: We performed a randomized, controlled, triple-blind study. The children were divided into the control group (CG; sorbitol 10%, n=29 or the experimental group (EG; 10 mg Zn/day, n=31, and the duration of the experiment was 3 months. Anthropometric assessments were performed for all of the children. Results: The body mass index-for-age increased after oral zinc supplementation in the EG (p=0.005. BIVA indicated that the CG demonstrated a tendency for dehydration and decreased soft tissue and the EG demonstrated a tendency for increased soft tissue, primarily the fat-free mass. After analyses of BIVA ellipses, we observed that this method could detect improvements in body composition in healthy children supplemented with zinc. Conclusions: These results suggest that BIVA could be an auxiliary method for studying a small population undergoing zinc intervention.

  20. Bioelectricity-assisted partial degradation of linear polyacrylamide in a bioelectrochemical system.

    Science.gov (United States)

    Cui, Yu-Zhi; Zhang, Jian; Sun, Min; Zhai, Lin-Feng

    2015-01-01

    The wide application of water-soluble linear polyacrylamides (PAMs) can cause serious environmental pollution. Biological treatment of PAMs receives very limited efficiency due to their recalcitrance to the microbial degradation. Here, we show the bioelectrochemical system (BES) can be used as an effective strategy to improve the biodegradation efficiency of PAMs. A linear PAM with viscosity-average molecular weight of 5 × 10(6) was treated in the anodic chamber of BES reactor, and the change of PAM structure during the degradation process was investigated. The anodic bacteria in the BES demonstrated abilities to utilize the PAM as the sole carbon and nitrogen source to generate electricity. Both the anode-attached and planktonic bacteria contributed to the electricity generation, while the anode-attached community exhibited stronger electron transfer ability than the planktonic one. The closed-circuit and open-circuit operations of the BES reactor obtained chemical oxygen demand (COD) removal efficiencies of 32.5 and 7.4 %, respectively, implying the generation of bioelectricity could enhance the biodegradation of PAM. Structure analysis suggested the carbon chain of PAM was partially degraded in the BES, producing polymeric products with lower molecular weight. The microbial cleavage of the carbon chain was proposed to start from the "head-to-head" linkages and end with the formation of ether bonds.

  1. Smartphone-Based Bioelectrical Impedance Analysis Devices for Daily Obesity Management.

    Science.gov (United States)

    Choi, Ahyoung; Kim, Justin Younghyun; Jo, Seongwook; Jee, Jae Hwan; Heymsfield, Steven B; Bhagat, Yusuf A; Kim, Insoo; Cho, Jaegeol

    2015-01-01

    Current bioelectric impedance analysis (BIA) systems are often large, cumbersome devices which require strict electrode placement on the user, thus inhibiting mobile capabilities. In this work, we developed a handheld BIA device that measures impedance from multiple frequencies (5 kHz~200 kHz) with four contact electrodes and evaluated the BIA device against standard body composition analysis systems: a dual-energy X-ray absorptiometry (DXA) system (GE Lunar Prodigy, GE Healthcare, Buckinghamshire, UK) and a whole-body BIA system (InBody S10, InBody, Co. Ltd, Seoul, Korea). In the study, 568 healthy participants, varying widely in body mass index, age, and gender, were recruited at two research centers: the Samsung Medical Center (SMC) in South Korea and the Pennington Biomedical Research Center (PBRC) in the United States. From the measured impedance data, we analyzed individual body fat and skeletal muscle mass by applying linear regression analysis against target reference data. Results indicated strong correlations of impedance measurements between the prototype pathways and corresponding InBody S10 electrical pathways (R = 0.93, p 0.728 (paired t-test), DXA mean body fat 29.45 ± 10.77 kg, estimated body fat 29.52 ± 12.53 kg). Thus, this portable BIA system shows a promising ability to estimate an individual's body composition that is comparable to large stationary BIA systems. PMID:26364636

  2. Body composition analysis in older adults with dementia. Anthropometry and bioelectrical impedance analysis: a critical review.

    Science.gov (United States)

    Camina Martín, M A; de Mateo Silleras, B; Redondo del Río, M P

    2014-11-01

    In clinical practice, geriatric nutritional assessment usually includes nutritional screening, a simple anthropometric assessment, measurement of various biochemical parameters, such as serum albumin, and sometimes (not always) body composition analysis (BCA). However, there is a high prevalence of undiagnosed malnutrition in patients with dementia. Several factors contribute to this situation; probably, the most notable is the methodology used to assess body composition (BC). In this regard, for BCA, techniques are needed that are noninvasive, affordable, safe, simple and that require the minimum possible collaboration by the elderly patient. Consequently, body mass index (BMI) and waist circumference (WC) are widely used as indicators of overall and central adiposity, respectively; however, there is no consensus on the cutoffs for the elderly, and changes in BC (especially muscle-mass depletion) are masked by normal values of BMI and WC. Bioimpedance analysis is a simple, cost-effective and precise method for BCA, provided that cross-validated equations are used. Its main disadvantage is that it is highly sensitive to changes in body water (overhydration or dehydration), leading to substantial errors in BC estimates. However, using Bioelectrical Impedance Vector Analysis errors are minimized, as there is no need for the subject to be normally hydrated and it does not require the use of predictive models. PMID:25117995

  3. Improvement of human keratinocyte migration by a redox active bioelectric dressing.

    Directory of Open Access Journals (Sweden)

    Jaideep Banerjee

    Full Text Available Exogenous application of an electric field can direct cell migration and improve wound healing; however clinical application of the therapy remains elusive due to lack of a suitable device and hence, limitations in understanding the molecular mechanisms. Here we report on a novel FDA approved redox-active Ag/Zn bioelectric dressing (BED which generates electric fields. To develop a mechanistic understanding of how the BED may potentially influence wound re-epithelialization, we direct emphasis on understanding the influence of BED on human keratinocyte cell migration. Mapping of the electrical field generated by BED led to the observation that BED increases keratinocyte migration by three mechanisms: (i generating hydrogen peroxide, known to be a potent driver of redox signaling, (ii phosphorylation of redox-sensitive IGF1R directly implicated in cell migration, and (iii reduction of protein thiols and increase in integrinαv expression, both of which are known to be drivers of cell migration. BED also increased keratinocyte mitochondrial membrane potential consistent with its ability to fuel an energy demanding migration process. Electric fields generated by a Ag/Zn BED can cross-talk with keratinocytes via redox-dependent processes improving keratinocyte migration, a critical event in wound re-epithelialization.

  4. Improvement of human keratinocyte migration by a redox active bioelectric dressing.

    Science.gov (United States)

    Banerjee, Jaideep; Das Ghatak, Piya; Roy, Sashwati; Khanna, Savita; Sequin, Emily K; Bellman, Karen; Dickinson, Bryan C; Suri, Prerna; Subramaniam, Vish V; Chang, Christopher J; Sen, Chandan K

    2014-01-01

    Exogenous application of an electric field can direct cell migration and improve wound healing; however clinical application of the therapy remains elusive due to lack of a suitable device and hence, limitations in understanding the molecular mechanisms. Here we report on a novel FDA approved redox-active Ag/Zn bioelectric dressing (BED) which generates electric fields. To develop a mechanistic understanding of how the BED may potentially influence wound re-epithelialization, we direct emphasis on understanding the influence of BED on human keratinocyte cell migration. Mapping of the electrical field generated by BED led to the observation that BED increases keratinocyte migration by three mechanisms: (i) generating hydrogen peroxide, known to be a potent driver of redox signaling, (ii) phosphorylation of redox-sensitive IGF1R directly implicated in cell migration, and (iii) reduction of protein thiols and increase in integrinαv expression, both of which are known to be drivers of cell migration. BED also increased keratinocyte mitochondrial membrane potential consistent with its ability to fuel an energy demanding migration process. Electric fields generated by a Ag/Zn BED can cross-talk with keratinocytes via redox-dependent processes improving keratinocyte migration, a critical event in wound re-epithelialization.

  5. New process for copper migration by bioelectricity generation in soil microbial fuel cells.

    Science.gov (United States)

    Wang, Hui; Song, Hailiang; Yu, Ran; Cao, Xian; Fang, Zhou; Li, Xianning

    2016-07-01

    The soil microbial fuel cell (MFC) is a promising biotechnology for the bioelectricity recovery as well as the remediation soil. Moreover, there were no studies on the heavy metal pollution in a soil MFC yet. A soil MFC was constructed to remediate the contaminated soil, and the electric field was generated from the oxidation of the acetate at the anode. We demonstrated the copper migration, the power generation, and the pH variation in the soil and the electrodes. The maximal voltage and the power density of 539 mV and 65.77 m W/m(2) were obtained in the soil MFC. The chemical fractionation of copper (Cu) was analyzed with a modified BCR sequential extraction method. The soluble Cu form and the total Cu contents from the anode to the cathode increased, and the difference between them kept growing over time. The Cu fractions in the soil and the electrodes were converted with the change of the dramatic pH from the anode to the cathode. There was a focusing effect leading to the change of the Cu forms, and the extractable acid form content increased in the three fifths where the acid and the alkali fronts met. PMID:27005277

  6. Bioelectricity generation and microcystins removal in a blue-green algae powered microbial fuel cell

    International Nuclear Information System (INIS)

    Bioelectricity production from blue-green algae was examined in a single chamber tubular microbial fuel cell (MFC). The blue-green algae powered MFC produced a maximum power density of 114 mW/m2 at a current density of 0.55 mA/m2. Coupled with the bioenergy generation, high removal efficiencies of chemical oxygen demand (COD) and nitrogen were also achieved in MFCs. Over 78.9% of total chemical oxygen demand (TCOD), 80.0% of soluble chemical oxygen demand (SCOD), 91.0% of total nitrogen (total-N) and 96.8% ammonium-nitrogen (NH3-N) were removed under closed circuit conditions in 12 days, which were much more effective than those under open circuit and anaerobic reactor conditions. Most importantly, the MFC showed great ability to remove microcystins released from blue-green algae. Over 90.7% of MC-RR and 91.1% of MC-LR were removed under closed circuit conditions (500 Ω). This study showed that the MFC could provide a potential means for electricity production from blue-green algae coupling algae toxins removal.

  7. Analysis of body water compartments after a short sauna bath using bioelectric impedance analysis.

    Science.gov (United States)

    Servidio, M-F; Mohamed, E I; Maiolo, C; Hereba, A T; Perrone, F; Garofano, P; Iacopino, L

    2003-10-01

    Studies have suggested that long-term sauna bathing may lower blood pressure in persons with hypertension by causing a direct loss of extracellular water and plasma minerals. The objective of the present study was to evaluate the effect of short-term sauna bathing on body water compartments as estimated by bioelectric impedance analysis (BIA). We recruited 15 men [mean age (+/-SD) of 23.93+/-5.12 years and mean body mass index (BMI) of 23.25+/-2.84 kg/m(2)] and 10 women matched for age and BMI. Total body resistance, reactance, and impedance were measured for all participants using BIA, at baseline, after a short sauna bath, and after a rest period. Total, extracellular, and intracellular water compartments were calculated using BIA formulae. There were no significant differences for any of the body water compartments when comparing the measurements taken before and after the sauna bath and after the rest period. However, it remains to be determined whether or not BIA is sensitive to rapid changes in water volume.

  8. Evoked bioelectrical activity of efferent fibers of the sciatic nerve of white rats in experimental menopause

    Directory of Open Access Journals (Sweden)

    Rodinsky A.G.

    2016-03-01

    Full Text Available The aim of our work was analysis of the bioelectrical activity of efferent fibers of the sciatic nerve in experimental menopause condition. Experiments were performed on 25 female white rats, divided into experimental and control groups. Menopause was modeled by total ovariohysterectomy. In 120 days after modeling we had recorded evoked action potentials of fibers of isolated ventral root L5 induced by stimulation of sciatic nerve with rectangular pulses. Threshold, chronaxia, latency, amplitude and duration of the action potential (AP were analysed. Refractory phenomenon was investigated by applying paired stimuli at intervals of 2 to 20 ms. In the context of long-term hypoestrogenemy threshold of AP appearance was 55,32±7,69%, chronaxy – 115,09±2,67%, latent period – 112,62±1,74% as compared with the control animals (p<0.01. In conditions of paired stimuli applying the amplitude of response to the testing stimulus in animals with ovariohysterectomy at intervals 3 and 4 ms was 61,25±36,45% and 53,48±18,64% (p<0.05 respectively.

  9. Validity of Bioelectrical Impedance Analysis to Estimation Fat-Free Mass in the Army Cadets

    Directory of Open Access Journals (Sweden)

    Raquel D. Langer

    2016-03-01

    Full Text Available Background: Bioelectrical Impedance Analysis (BIA is a fast, practical, non-invasive, and frequently used method for fat-free mass (FFM estimation. The aims of this study were to validate predictive equations of BIA to FFM estimation in Army cadets and to develop and validate a specific BIA equation for this population. Methods: A total of 396 males, Brazilian Army cadets, aged 17–24 years were included. The study used eight published predictive BIA equations, a specific equation in FFM estimation, and dual-energy X-ray absorptiometry (DXA as a reference method. Student’s t-test (for paired sample, linear regression analysis, and Bland–Altman method were used to test the validity of the BIA equations. Results: Predictive BIA equations showed significant differences in FFM compared to DXA (p < 0.05 and large limits of agreement by Bland–Altman. Predictive BIA equations explained 68% to 88% of FFM variance. Specific BIA equations showed no significant differences in FFM, compared to DXA values. Conclusion: Published BIA predictive equations showed poor accuracy in this sample. The specific BIA equations, developed in this study, demonstrated validity for this sample, although should be used with caution in samples with a large range of FFM.

  10. Enhanced bioelectricity harvesting in microbial fuel cells treating food waste leachate produced from biohydrogen fermentation.

    Science.gov (United States)

    Choi, Jeongdong; Ahn, Youngho

    2015-05-01

    Microbial fuel cells (MFCs) treating the food waste leachate produced from biohydrogen fermentation were examined to enhance power generation and energy recovery. In batch mode, the maximum voltage production was 0.56 V and the power density reached 1540 mW/m(2). The maximum Coulombic efficiency (CEmax) and energy efficiency (EE) in the batch mode were calculated to be 88.8% and 18.8%, respectively. When the organic loading rate in sequencing batch mode varied from 0.75 to 6.2 g COD/L-d (under CEmax), the maximum power density reached 769.2 mW/m(2) in OLR of 3.1 g COD/L-d, whereas higher energy recovery (CE=52.6%, 0.346 Wh/g CODrem) was achieved at 1.51 g COD/L-d. The results demonstrate that readily biodegradable substrates in biohydrogen fermentation can be effectively used for the enhanced bioelectricity harvesting of MFCs and a MFC coupled with biohydrogen fermentation is of great benefit on higher electricity generation and energy efficiency.

  11. Bioelectrical impedance analysis determination of water content and distribution in the horse.

    Science.gov (United States)

    Latman, Neal S; Keith, Natalie; Nicholson, Alan; Davis, Michael

    2011-06-01

    A horse's hydration status is critical to its health. The accurate and quantitative determination of it has been problematic because of size, length and density of hair, and uneven topography. The objective of this study was to validate a bioelectrical impedance analysis (BIA) method for objectively quantifying hydration status. Monofrequency BIA values and simple biometric measurements were used to construct predictive equations for total body water, plasma, extracellular, and intra-cellular fluid volumes. These predictive equations were correlated with standard body fluid dilution reference methods. The result was an accuracy of ±0.64% for total body water, ±0.17% for plasma volume, ±1.91% for extra-cellular fluid, and ±0.57% for intra-cellular fluid compartments. Less than 5 min was required for all of the measurements and determinations. Therefore, it appears that an accurate measurement of body fluid distribution can be performed on horses using a fast, easy, non-invasive, inexpensive BIA method.

  12. Prediction of fat-free body mass from bioelectrical impedance and anthropometry among 3-year-old children using DXA

    DEFF Research Database (Denmark)

    Ejlerskov, Katrine Tschentscher; Jensen, Signe Marie; Christensen, Line B;

    2014-01-01

    For 3-year-old children suitable methods to estimate body composition are sparse. We aimed to develop predictive equations for estimating fat-free mass (FFM) from bioelectrical impedance (BIA) and anthropometry using dual-energy X-ray absorptiometry (DXA) as reference method using data from 99...... healthy 3-year-old Danish children. Predictive equations were derived from two multiple linear regression models, a comprehensive model (height(2)/resistance (RI), six anthropometric measurements) and a simple model (RI, height, weight). Their uncertainty was quantified by means of 10-fold cross...

  13. Smartphone-Based Bioelectrical Impedance Analysis Devices for Daily Obesity Management

    Directory of Open Access Journals (Sweden)

    Ahyoung Choi

    2015-09-01

    Full Text Available Current bioelectric impedance analysis (BIA systems are often large, cumbersome devices which require strict electrode placement on the user, thus inhibiting mobile capabilities. In this work, we developed a handheld BIA device that measures impedance from multiple frequencies (5 kHz~200 kHz with four contact electrodes and evaluated the BIA device against standard body composition analysis systems: a dual-energy X-ray absorptiometry (DXA system (GE Lunar Prodigy, GE Healthcare, Buckinghamshire, UK and a whole-body BIA system (InBody S10, InBody, Co. Ltd, Seoul, Korea. In the study, 568 healthy participants, varying widely in body mass index, age, and gender, were recruited at two research centers: the Samsung Medical Center (SMC in South Korea and the Pennington Biomedical Research Center (PBRC in the United States. From the measured impedance data, we analyzed individual body fat and skeletal muscle mass by applying linear regression analysis against target reference data. Results indicated strong correlations of impedance measurements between the prototype pathways and corresponding InBody S10 electrical pathways (R = 0.93, p < 0.0001. Additionally, body fat estimates from DXA did not yield significant differences (p > 0.728 (paired t-test, DXA mean body fat 29.45 ± 10.77 kg, estimated body fat 29.52 ± 12.53 kg. Thus, this portable BIA system shows a promising ability to estimate an individual’s body composition that is comparable to large stationary BIA systems.

  14. Conversion of orange peel waste biomass to bioelectricity using a mediator-less microbial fuel cell.

    Science.gov (United States)

    Miran, Waheed; Nawaz, Mohsin; Jang, Jiseon; Lee, Dae Sung

    2016-03-15

    Microorganisms have the potential to become a game-changer in sustainable energy production in the coming generations. Microbial fuel cells (MFCs) as an alternative renewable technology can capture bioenergy (electricity) from carbon-based sources by utilizing microorganisms as biocatalysts. This study demonstrated that MFC technology can be explored for bioelectricity production from orange peel waste (OPW), an agricultural byproduct and an organic substrate, without any chemical pretreatment or the addition of extra mediators. A maximum voltage generation of 0.59 ± 0.02 V (at 500 Ω) was achieved in a dual chamber MFC during stable voltage generation stages. The maximum power density and current density obtained were 358.8 ± 15.6 mW/m(2) and 847 ± 18.4 mA/m(2), respectively. Key components of OPW, namely pectin and cellulose, were also tested in their pure form, with pectin giving a stable current, while no significant current generation was achieved using cellulose alone as the substrate, thus demonstrating the absence of cellulose-degrading bacteria. Maximum pectinase and polygalacturonase enzyme activities of 18.55 U/g and 9.04 U/g (per gram of substrate), respectively were achieved during orange peel degradation in MFCs. Bacterial identification using 16S rRNA analysis of the initial inoculum fed to the MFC, the biofilm attached to the anode, and the anode suspension, showed significant diversity in community composition. A well-known exoelectrogen, Pseudomonas, was present among the predominant genera in the anode biofilm. PMID:26780146

  15. Hexavalent chromium removal and bioelectricity generation by Ochrobactrum sp. YC211 under different oxygen conditions.

    Science.gov (United States)

    Chen, Chih-Yu; Cheng, Chiu-Yu; Chen, Ching-Kuo; Hsieh, Min-Chi; Lin, Ssu-Ting; Ho, Kuo-Ying; Li, Jo-Wei; Lin, Chia-Pei; Chung, Ying-Chien

    2016-01-01

    Bioremediation is an environmentally friendly method of reducing heavy metal concentration and toxicity. A chromium-reducing bacterial strain, isolated from the vicinity of an electroplate factory, was identified as Ochrobactrum sp. YC211. The efficiency and capacity per time of Ochrobactrum sp. YC211 for hexavalent chromium (Cr(VI)) removal under anaerobic conditions were superior to those under aerobic conditions. An acceptable removal efficiency (96.5 ± 0.6%) corresponding to 30.2 ± 0.8 mg-Cr (g-dry cell weight-h)(-1) was achieved by Ochrobactrum sp. YC211 at 300 mg L(-1) Cr(VI). A temperature of 30°C and pH 7 were the optimal parameters for Cr(VI) removal. By examining reactivated cells, permeabilized cells, and cell-free extract, we determined that Cr(VI) removal by Ochrobactrum sp. YC211 under anaerobic conditions mainly occurred in the soluble fraction of the cell and can be regarded as an enzymatic reaction. The results also indicated that an Ochrobactrum sp. YC211 microbial fuel cell (MFC) with an anaerobic anode was considerably superior to that with an aerobic anode in bioelectricity generation and Cr(VI) removal. The maximum power density and Cr(VI) removal efficiency of the MFC were 445 ± 3.2 mW m(-2) and 97.2 ± 0.3%, respectively. Additionally, the effects of coexisting ions (Cu(2+), Zn(2+), Ni(2+), SO4(2-), and Cl(-)) in the anolyte on the MFC performance and Cr(VI) removal were nonsignificant (P > 0.05). To our knowledge, this is the first report to compare Cr(VI) removal by different cells and MFC types under aerobic and anaerobic conditions. PMID:26889692

  16. Body composition measures of obese adolescents by the deuterium oxide dilution method and by bioelectrical impedance

    Directory of Open Access Journals (Sweden)

    C.M.M. Resende

    2011-11-01

    Full Text Available The objectives of the present study were to describe and compare the body composition variables determined by bioelectrical impedance (BIA and the deuterium dilution method (DDM, to identify possible correlations and agreement between the two methods, and to construct a linear regression model including anthropometric measures. Obese adolescents were evaluated by anthropometric measures, and body composition was assessed by BIA and DDM. Forty obese adolescents were included in the study. Comparison of the mean values for the following variables: fat body mass (FM; kg, fat-free mass (FFM; kg, and total body water (TBW; % determined by DDM and by BIA revealed significant differences. BIA overestimated FFM and TBW and underestimated FM. When compared with data provided by DDM, the BIA data presented a significant correlation with FFM (r = 0.89; P < 0.001, FM (r = 0.93; P < 0.001 and TBW (r = 0.62; P < 0.001. The Bland-Altman plot showed no agreement for FFM, FM or TBW between data provided by BIA and DDM. The linear regression models proposed in our study with respect to FFM, FM, and TBW were well adjusted. FFM obtained by DDM = 0.842 x FFM obtained by BIA. FM obtained by DDM = 0.855 x FM obtained by BIA + 0.152 x weight (kg. TBW obtained by DDM = 0.813 x TBW obtained by BIA. The body composition results of obese adolescents determined by DDM can be predicted by using the measures provided by BIA through a regression equation.

  17. Estimation of fat-free mass in Asian neonates using bioelectrical impedance analysis.

    Science.gov (United States)

    Tint, Mya-Thway; Ward, Leigh C; Soh, Shu E; Aris, Izzuddin M; Chinnadurai, Amutha; Saw, Seang Mei; Gluckman, Peter D; Godfrey, Keith M; Chong, Yap-Seng; Kramer, Michael S; Yap, Fabian; Lingwood, Barbara; Lee, Yung Seng

    2016-03-28

    The aims of this study were to develop and validate a prediction equation of fat-free mass (FFM) based on bioelectrical impedance analysis (BIA) and anthropometry using air-displacement plethysmography (ADP) as a reference in Asian neonates and to test the applicability of the prediction equations in an independent Western cohort. A total of 173 neonates at birth and 140 at two weeks of age were included. Multiple linear regression analysis was performed to develop the prediction equations in a two-third randomly selected subset and validated on the remaining one-third subset at each time point and in an independent Queensland cohort. FFM measured by ADP was the dependent variable, and anthropometric measures, sex and impedance quotient (L2/R50) were independent variables in the model. Accuracy of prediction equations was assessed using intra-class correlation and Bland-Altman analyses. L2/R50 was the significant predictor of FFM at week two but not at birth. Compared with the model using weight, sex and length, including L2/R50 slightly improved the prediction with a bias of 0·01 kg with 2 sd limits of agreement (LOA) (0·18, -0·20). Prediction explained 88·9 % of variation but not beyond that of anthropometry. Applying these equations to the Queensland cohort provided similar performance at the appropriate age. However, when the Queensland equations were applied to our cohort, the bias increased slightly but with similar LOA. BIA appears to have limited use in predicting FFM in the first few weeks of life compared with simple anthropometry in Asian populations. There is a need for population- and age-appropriate FFM prediction equations. PMID:26856420

  18. Bioimpedance Vector Pattern in Taiwanese and Polish College Students Detected by Bioelectric Impedance Vector Analysis: Preliminary Observations

    Directory of Open Access Journals (Sweden)

    Teresa Malecka-Massalska

    2012-01-01

    Full Text Available Background and Objectives. The study was conducted to evaluate soft tissue hydration and mass through pattern analysis of vector plots as height, normalized resistance, and reactance measurements by bioelectric impedance vector analysis in Taiwanese and Polish college students. Methods. Whole-body measurements were made with ImpediMed bioimpedance analysis SFB7 BioImp v1.55 (Pinkenba Qld 4008, Australia in 16 Taiwanese and Polish men and 16 Taiwanese and Polish women. Results. Mean vectors of Taiwanese men and women groups versus the Polish men and women groups were characterized by almost the same normalized resistance component with reactance component (separate 95% confidence limits, <0.05 indicating that there were no differences of soft tissue hydration and mass. Interpretation and Conclusion. The evaluation of soft tissue hydration and mass through pattern analysis of vector plots as height, normalized resistance, and reactance measurements by bioelectric impedance vector analysis in Taiwanese and Polish college students did not differ between these two diverse ethnic groups. Further observational research investigating these properties in larger groups would be welcomed to elucidate and/or confirm these findings.

  19. Bioelectrical impedance analysis and anthropometry for the determination of body composition in rats: effects of high-fat and high-sucrose diets

    Directory of Open Access Journals (Sweden)

    Larissa Rodrigues Neto Angéloco

    2012-06-01

    Full Text Available OBJECTIVE: The aim of the present study was to determine the impedance of Wistar rats treated with high-fat and high-sucrose diets and correlate their biochemical and anthropometric parameters with chemical analysis of the carcass. METHODS: Twenty-four male Wistar rats were fed a standard (AIN-93, high-fat (50% fat or high-sucrose (59% of sucrose diet for 4 weeks. Abdominal and thoracic circumference and body length were measured. Bioelectrical impedance analysis was used to determine resistance and reactance. Final body composition was determined by chemical analysis. RESULTS: Higher fat intake led to a high percentage of liver fat and cholesterol and low total body water in the High-Fat group, but these changes in the biochemical profile were not reflected by the anthropometric measurements or bioelectrical impedance analysis variables. Anthropometric and bioelectrical impedance analysis changes were not observed in the High-Sucrose group. However, a positive association was found between body fat and three anthropometric variables: body mass index, Lee index and abdominal circumference. CONCLUSION: Bioelectrical impedance analysis did not prove to be sensitive for detecting changes in body composition, but body mass index, Lee index and abdominal circumference can be used for estimating the body composition of rats.

  20. The Effect of an Acute After-School Exercise Bout on Percentage of Body Fat Using Leg-to-Leg Bioelectrical Impedance Analysis in Children

    Science.gov (United States)

    Andreacci, Joseph L.; Dixon, Curt B.; Rompolski, Krista; VanGorden, Kelly M.

    2008-01-01

    Bioelectrical impedance analysis (BIA) is a fast, easy to administer, and relatively inexpensive method of evaluating body composition. Due to the ease of operation, interest in using BIA to estimate percentage of body fat (%BF) has grown, especially in settings where body composition assessments are often performed without the benefit of…

  1. Bioelectrical impedance analysis in clinical practice: implications for hepatitis C therapy BIA and hepatitis C

    Directory of Open Access Journals (Sweden)

    Kahraman Alisan

    2010-08-01

    Full Text Available Abstract Background Body composition analysis using phase angle (PA, determined by bioelectrical impedance analysis (BIA, reflects tissue electrical properties and has prognostic value in liver cirrhosis. Objective of this prospective study was to investigate clinical use and prognostic value of BIA-derived phase angle and alterations in body composition for hepatitis C infection (HCV following antiviral therapy. Methods 37 consecutive patients with HCV infection were enrolled, BIA was performed, and PA was calculated from each pair of measurements. 22 HCV genotype 3 patients treated for 24 weeks and 15 genotype 1 patients treated for 48 weeks, were examined before and after antiviral treatment and compared to 10 untreated HCV patients at 0, 24, and 48 weeks. Basic laboratory data were correlated to body composition alterations. Results Significant reduction in body fat (BF: 24.2 ± 6.7 kg vs. 19.9 ± 6.6 kg, genotype1; 15.4 ± 10.9 kg vs. 13.2 ± 12.1 kg, genotype 3 and body cell mass (BCM: 27.3 ± 6.8 kg vs. 24.3 ± 7.2 kg, genotype1; 27.7 ± 8.8 kg vs. 24.6 ± 7.6 kg, genotype 3 was found following treatment. PA in genotype 3 patients was significantly lowered after antiviral treatment compared to initial measurements (5.9 ± 0.7° vs. 5.4 ± 0.8°. Total body water (TBW was significantly decreased in treated patients with genotype 1 (41.4 ± 7.9 l vs. 40.8 ± 9.5 l. PA reduction was accompanied by flu-like syndromes, whereas TBW decline was more frequently associated with fatigue and cephalgia. Discussion BIA offers a sophisticated analysis of body composition including BF, BCM, and TBW for HCV patients following antiviral regimens. PA reduction was associated with increased adverse effects of the antiviral therapy allowing a more dynamic therapy application.

  2. Evaluation of body composition in COPD patients using multifrequency bioelectrical impedance analysis

    Science.gov (United States)

    de Blasio, Francesca; de Blasio, Francesco; Miracco Berlingieri, Giulia; Bianco, Andrea; La Greca, Marta; Franssen, Frits M E; Scalfi, Luca

    2016-01-01

    Background Multifrequency bioelectrical impedance analysis (MF-BIA) is a technique that measures body impedance (Z) at different frequencies (5, 10, 50, 100, and 250 kHz). Body composition may be estimated using empirical equations, which include BIA variables or, alternatively, raw BIA data may provide direct information on water distribution and muscle quality. Objectives To compare raw MF-BIA data between COPD patients and controls and to study their relationship with respiratory and functional parameters in COPD patients. Methods MF-BIA was performed (Human Im-Touch analyzer) in 212 COPD patients and 115 age- and BMI-matched controls. Fat-free mass (FFM) and fat mass were estimated from BIA data, and low- to high-frequency (5 kHz/250 kHz) impedance ratio was calculated. Physical fitness, lung function and respiratory muscle strength were also assessed in COPD patients. Results After adjusting for age, weight, and body mass index, FFM and the 5/250 impedance ratio were lower in COPD patients (P<0.001) and were negatively affected by disease severity. In both male and female patients, the 5/250 impedance ratio was significantly correlated mainly with age (r=−0.316 and r=−0.346, respectively). Patients with a 5/250 impedance ratio below median value had lower handgrip strength (P<0.001), 6-minute walk distance (P<0.005), respiratory muscle strength (P<0.005), forced expiratory volume in 1 second (P<0.05) and vital capacity (P<0.005). Finally, the 5/250 impedance ratio was reduced (P<0.05) in patients with Global Initiative for Chronic Obstructive Lung Disease (GOLD) III and IV (compared to those with GOLD I and II) or a BODE index between 6 and 10 points (compared to those with BODE index between 1 and 5 points). Conclusion MF-BIA may be a useful tool for assessing body composition and nutritional status in COPD patients. In particular, the impedance ratio could give valuable information on cellular integrity and muscle quality.

  3. Validation of Bioelectrical Impedance Spectroscopy to Measure Total Body Water in Resistance-Trained Males.

    Science.gov (United States)

    Kerr, Ava; Slater, Gary; Byrne, Nuala; Chaseling, Janet

    2015-10-01

    The three-compartment (3-C) model of physique assessment (fat mass, fat-free mass, water) incorporates total body water (TBW) whereas the two-compartment model (2-C) assumes a TBW of 73.72%. Deuterium dilution (D2O) is the reference method for measuring TBW but is expensive and time consuming. Multifrequency bioelectrical impedance spectroscopy (BIS SFB7) estimates TBW instantaneously and claims high precision. Our aim was to compare SFB7 with D2O for estimating TBW in resistance trained males (BMI >25kg/m2). We included TBWBIS estimates in a 3-C model and contrasted this and the 2-C model against the reference 3-C model using TBWD2O. TBW of 29 males (32.4 ± 8.5 years; 183.4 ± 7.2 cm; 92.5 ± 9.9 kg; 27.5 ± 2.6 kg/m2) was measured using SFB7 and D2O. Body density was measured by BODPOD, with body composition calculated using the Siri equation. TBWBIS values were consistent with TBWD2O (SEE = 2.65L; TE = 2.6L) as were %BF values from the 3-C model (BODPOD + TBWBIS) with the 3-C reference model (SEE = 2.20%; TE = 2.20%). For subjects with TBW more than 1% from the assumed 73.72% (n = 16), %BF from the 2-C model differed significantly from the reference 3-C model (Slope 0.6888; Intercept 5.093). The BIS SFB7 measured TBW accurately compared with D2O. The 2C model with an assumed TBW of 73.72% introduces error in the estimation of body composition. We recommend TBW should be measured, either via the traditional D2O method or when resources are limited, with BIS, so that body composition estimates are enhanced. The BIS can be accurately used in 3C equations to better predict TBW and BF% in resistance trained males compared with a 2C model. PMID:26011918

  4. 食蚊鱼的生物电场特征%THE BIOELECTRIC FIELD OF GAMBUSIA AFFINIS

    Institute of Scientific and Technical Information of China (English)

    张旭光; 宋佳坤; 张国胜; 范纯新; 郭弘艺; 王晓杰

    2011-01-01

    Sturgeon is an ancestor electrosensory fish which is able to sense the electric fields of prey animals and other sources. The character of bioelectric fields in environment is an important stimulus to investigate the electrosensory information processing in the brain. However, there were a few documents on bioelectric fields. In this study, the bioelectric fields of Gambusia affinis were measured in living fish, which was used as prey fish of Siberian Sturgeon in laboratory and the common small fish in southern China. They were measured and charactered in three experimental groups: single fish group, pair in same direction group and pair in opposite direction group. The bioelectric field of single fish showed typical features of dipole field, with relative potential up to (-24±2.4) uV on head and (21 ±1.6) uV on tail. There was (4.2±0.8) uV alternating current electric with 1-3 Hz on head which was corresponded with the respiratory rhythm of the fish. In other two experimental groups, the direct current electric fields were larger than the single fish group (P<0.05). However, the alternating current electric field of single fish group was significant bigger than pair in opposite direction group (3.8±0.7) uV but smaller than pairs in same direction group (4.5±0.8) uV (P<0.01). It suggested that the schooling fish could evade the predators by modulating the alternating current respiratory potential. It was maybe a kind of ancestral anti-predator strategy for fish to meet the passive electroreception, and further research would carry on electrophysiology.%文章采用活体记录的方法测量了食蚊鱼(Gambusia affinis)的生物电场.实验分单尾鱼、两尾鱼同向和两尾鱼反向三组测量,每组10个重复.结果表明:单尾鱼的生物电场表现为头负、尾正的偶极子直流电场,头部相对电势为(-24±2.4)μ v,尾部为(21±1 6)μ v,且头部附近产生1-3 Hz与呼吸频率对应的交流呼吸电场,大小为(4.2±0.8)μV.两尾

  5. Integrative assessment of kick boxers’ brain blood circulation and bio-electrical activity in conditions of correction technologies’ application

    Directory of Open Access Journals (Sweden)

    Romanov Y.N.

    2016-06-01

    Full Text Available Purpose: to scientifically substantiate the role of para-vertebral impacts on blood circulation and bio-electrical activity of kick boxers’ cortex. Material: in the research participated kick boxers (main group, n=62 and university students (control group, n=25 of 18-23 years’ age. Assessment of para-vertebral impacts with device Armos and classic massage was fulfilled with the help of the following methodic: trans-cranial dopplerography of head main arteries and cortex EEG of the tested. Results: it was found that with the help of para-vertebral impacts by device Armos linear velocity of cerebral blood flow reduces to normal limits and in- and inter-hemispheres’ interaction strength increases. Conclusions: para-vertebral impacts by device Armos activate integrative processes and inter-hemispheres’ interactions of different cortex areas of kick boxers. It can witness about better formation of functional systems, ensuring sports efficiency.

  6. GHG emission factors for bioelectricity, biomethane, and bioethanol quantified for 24 biomass substrates with consequential life-cycle assessment

    DEFF Research Database (Denmark)

    Tonini, Davide; Hamelin, Lorie; Alvarado-Morales, Merlin;

    2016-01-01

    factors (EFs) for bioelectricity, biomethane, and bioethanol produced from twenty-four biomasses (from dedicated crops to residues of different origin) under a fossil and a non-fossil energy system. Accounting for numerous variations in the pathways, a total of 554 GHG EFs were quantified. The results...... showed that, important GHG savings were obtained with residues and seaweed, both under fossil and non-fossil energy systems. For high-yield perennial crops (e.g. willow and Miscanthus), GHG savings were achieved only under fossil energy systems. Biofuels from annual crops and residues that are today used...... in the feed sector should be discouraged, as LUC GHG emissions exceeded any GHG savings from displacing conventional energy sources. (C) 2016 Elsevier Ltd. All rights reserved....

  7. Evaluation of body composition in COPD patients using multifrequency bioelectrical impedance analysis

    Directory of Open Access Journals (Sweden)

    de Blasio F

    2016-09-01

    Full Text Available Francesca de Blasio,1 Francesco de Blasio,2,3 Giulia Miracco Berlingieri,2 Andrea Bianco,3,4 Marta La Greca,1 Frits M E Franssen,5 Luca Scalfi1 1Department of Public Health, Medical School, “Federico II” University of Naples, 2Respiratory Medicine and Pulmonary Rehabilitation Section, Clinic Center, Private Hospital, Naples, 3Department of Medicine and Health Sciences “V Tiberio”, University of Molise, Campobasso, 4Department of Cardio-Thoracic and Respiratory Sciences, Second University of Naples, Naples, Italy; 5Department of Research and Education, CIRO, Horn, the NetherlandsBackground: Multifrequency bioelectrical impedance analysis (MF-BIA is a technique that measures body impedance (Z at different frequencies (5, 10, 50, 100, and 250 kHz. Body composition may be estimated using empirical equations, which include BIA variables or, alternatively, raw BIA data may provide direct information on water distribution and muscle quality.Objectives: To compare raw MF-BIA data between COPD patients and controls and to study their relationship with respiratory and functional parameters in COPD patients.Methods: MF-BIA was performed (Human Im-Touch analyzer in 212 COPD patients and 115 age- and BMI-matched controls. Fat-free mass (FFM and fat mass were estimated from BIA data, and low- to high-frequency (5 kHz/250 kHz impedance ratio was calculated. Physical fitness, lung function and respiratory muscle strength were also assessed in COPD patients.Results: After adjusting for age, weight, and body mass index, FFM and the 5/250 impedance ratio were lower in COPD patients (P<0.001 and were negatively affected by disease severity. In both male and female patients, the 5/250 impedance ratio was significantly correlated mainly with age (r=−0.316 and r=−0.346, respectively. Patients with a 5/250 impedance ratio below median value had lower handgrip strength (P<0.001, 6-minute walk distance (P<0.005, respiratory muscle strength (P<0.005, forced

  8. Inter-sport variability of muscle volume distribution identified by segmental bioelectrical impedance analysis in four ball sports

    Directory of Open Access Journals (Sweden)

    Yamada Y

    2013-04-01

    Full Text Available Yosuke Yamada,1,2 Yoshihisa Masuo,3 Eitaro Nakamura,4 Shingo Oda5 1Laboratory of Sports and Health Science, Kyoto Prefectural University of Medicine, Kyoto, Japan; 2Japan Society for the Promotion of Science, Tokyo, Japan; 3Waseda University Research Institute for Elderly Health, Saitama, Japan; 4Department of Sport Science, Kyoto Iken College of Medicine and Health, Kyoto, Japan; 5Faculty of Health and Well-being, Kansai University, Osaka, Japan Abstract: The aim of this study was to evaluate and quantify differences in muscle distribution in athletes of various ball sports using segmental bioelectrical impedance analysis (SBIA. Participants were 115 male collegiate athletes from four ball sports (baseball, soccer, tennis, and lacrosse. Percent body fat (%BF and lean body mass were measured, and SBIA was used to measure segmental muscle volume (MV in bilateral upper arms, forearms, thighs, and lower legs. We calculated the MV ratios of dominant to nondominant, proximal to distal, and upper to lower limbs. The measurements consisted of a total of 31 variables. Cluster and factor analyses were applied to identify redundant variables. The muscle distribution was significantly different among groups, but the %BF was not. The classification procedures of the discriminant analysis could correctly distinguish 84.3% of the athletes. These results suggest that collegiate ball game athletes have adapted their physique to their sport movements very well, and the SBIA, which is an affordable, noninvasive, easy-to-operate, and fast alternative method in the field, can distinguish ball game athletes according to their specific muscle distribution within a 5-minute measurement. The SBIA could be a useful, affordable, and fast tool for identifying talents for specific sports. Keywords: discriminant analysis, cluster and factor analysis, segmental bioelectrical impedance analysis, baseball, lacrosse

  9. Handling uncertainty in bioenergy policy design – A case study analysis of UK and German bioelectricity policy instruments

    International Nuclear Information System (INIS)

    In designing policies to promote bioenergy, policy makers face challenges concerning uncertainties about the sustainability of bioenergy pathways (including greenhouse gas balances), technology and resource costs, or future energy market framework conditions. New information becomes available with time, but policy adjustments can involve high levels of adaptation costs. To enable an effective steering of technology choices and innovation, policies have to strike a balance between creating a consistent institutional framework, which establishes planning security for investors, and sufficient flexibility to adapt to new information. This paper examines implications of economic theory for handling cost and benefit uncertainty in bioelectricity policy design, focussing on choices between price and quantity instruments, technology differentiation, and policy adjustment. Findings are applied to two case studies, the UK's Renewables Obligation and the German feed-in tariff/feed-in premium scheme. Case study results show the trade-offs that are involved in instrument choice and design – depending on political priorities and a country's specific context, different options can prove more adequate. Combining market-based remuneration with sustainability criteria results in strong incentives for bioenergy producers to search for low-cost solutions; whereas cost-based price instruments with centrally steered technology and feedstock choices offer higher planning security for investors and more direct control for policy makers over what pathways are implemented. Independent of the choice of instrument type and technology differentiation mechanism, findings emphasise the importance of a careful policy design, which determines the exact balance between performance criteria such as cost control, incentive intensity, planning security and adaptive efficiency. - Highlights: • Bioelectricity policy design must deal with simultaneous cost and benefit uncertainty.

  10. DESCRIPTIVE PROFILE OF BODY STRUCTURE OF TOP GRECO-ROMAN STYLE WRESTLERS DEFINED WITH METHOD OF MULTICHANNEL BIOELECTRIC IMPEDANCE

    Directory of Open Access Journals (Sweden)

    Milivoj Dopsaj

    2012-12-01

    Full Text Available Because of the specificity of given sport and weight categories wrestlers are characterized by specific morphologic characteristics. With the development of new measurement technologies there are some new opportunities for the development of new ways of obtaining information relevant to the sports system. One of the new technologies, which are used in area of measurement of body composition structure, is a method of bioimpedace, and the latest generations use a variant of the multichannel bioelectrical bioimpedance. The goal of this study is to define morphological model of top senior wrestlers by using the latest technological methods that will revalidate the existing knowledge about the given area. The sample of respondents is made of 22 male wrestlers, Greco-Roman style, top senior level athletes from four different countries: Serbia (n = 10, Croatia (n = 9, Montenegro (n = 2 and Greece (n = 1. Measurement of body composition is made with method of multichannel bioelectric impedance with professional apparatus of latest generation - InBody 720 Tetrapolar 8-Point Tactile Electrode System (Biospace, Co., Ltd. The most important result of this research is definition of generic (general four-dimensional model (4D model of body composition with quality international level wrestlers with following characteristics: in regards to average body mass of sample wrestlers – 81.95 kg, the amount of water is 55.08 L or 67.24 %, the amount of proteins is 15.00 kg or 18.33%, minerals 4.98 kg or 5.97% and fat mass 6.99 kg or 8.49 %.

  11. Predictive validity of four bioelectrical impedance equations in determining percent fat mass in overweight and obese children.

    Science.gov (United States)

    Cleary, Jane; Daniells, Suzie; Okely, Anthony D; Batterham, Marijka; Nicholls, Jessie

    2008-01-01

    Bioelectrical impedance equations are frequently used by food and nutrition professionals to estimate percent fat mass in overweight and obese children. However, it is not known whether they are accurate for such children, as they have been primarily developed for children of varying body weights. The aim of this cross-sectional study was to evaluate the predictive validity of four previously published prediction equations developed for the pediatric population, among a sample of overweight and obese children. Thirty overweight or obese children (mean age=7.57+/-1.28 years) underwent measurement of fat mass, percent fat mass, and fat-free mass using dual-energy x-ray absorptiometry (DEXA) and bioelectrical impedance analysis (BIA). Impedance values from the BIA were entered into the four prediction equations and Pearson correlations used to determine the significance of associations between each of the BIA prediction equations and DEXA for percent fat mass, fat mass, and fat-free mass. For percent fat mass, paired t tests were used to assess differences between the methods and the technique of Bland and Altman was used to determine bias and error. Results showed that the mean percent fat mass as determined by DEXA for this age group was 40.79%. In comparison with other BIA prediction equations, the Schaefer equation had the closest mean value of 41.98%, and was the only equation not to significantly differ from the DEXA (P=0.121). This study suggests that the Schaefer equation is the only accurate BIA prediction equation for assessing percent fat mass in this sample of overweight and obese children from primarily white backgrounds. PMID:18156000

  12. Bioelectricity Generation and Bioremediation of an Azo-Dye in a Microbial Fuel Cell Coupled Activated Sludge Process.

    Science.gov (United States)

    Khan, Mohammad Danish; Abdulateif, Huda; Ismail, Iqbal M; Sabir, Suhail; Khan, Mohammad Zain

    2015-01-01

    Simultaneous bioelectricity generation and dye degradation was achieved in the present study by using a combined anaerobic-aerobic process. The anaerobic system was a typical single chambered microbial fuel cell (SMFC) which utilizes acid navy blue r (ANB) dye along with glucose as growth substrate to generate electricity. Four different concentrations of ANB (50, 100, 200 and 400 ppm) were tested in the SMFC and the degradation products were further treated in an activated sludge post treatment process. The dye decolorization followed pseudo first order kinetics while the negative values of the thermodynamic parameter ∆G (change in Gibbs free energy) shows that the reaction proceeds with a net decrease in the free energy of the system. The coulombic efficiency (CE) and power density (PD) attained peak values at 10.36% and 2,236 mW/m2 respectively for 200 ppm of ANB. A further increase in ANB concentrations results in lowering of cell potential (and PD) values owing to microbial inhibition at higher concentrations of toxic substrates. Cyclic voltammetry studies revealed a perfect redox reaction was taking place in the SMFC. The pH, temperature and conductivity remain 7.5-8.0, 27(±2°C and 10.6-18.2 mS/cm throughout the operation. The biodegradation pathway was studied by the gas chromatography coupled with mass spectroscopy technique, suggested the preferential cleavage of the azo bond as the initial step resulting in to aromatic amines. Thus, a combined anaerobic-aerobic process using SMFC coupled with activated sludge process can be a viable option for effective degradation of complex dye substrates along with energy (bioelectricity) recovery.

  13. Bioelectricity Generation and Bioremediation of an Azo-Dye in a Microbial Fuel Cell Coupled Activated Sludge Process.

    Directory of Open Access Journals (Sweden)

    Mohammad Danish Khan

    Full Text Available Simultaneous bioelectricity generation and dye degradation was achieved in the present study by using a combined anaerobic-aerobic process. The anaerobic system was a typical single chambered microbial fuel cell (SMFC which utilizes acid navy blue r (ANB dye along with glucose as growth substrate to generate electricity. Four different concentrations of ANB (50, 100, 200 and 400 ppm were tested in the SMFC and the degradation products were further treated in an activated sludge post treatment process. The dye decolorization followed pseudo first order kinetics while the negative values of the thermodynamic parameter ∆G (change in Gibbs free energy shows that the reaction proceeds with a net decrease in the free energy of the system. The coulombic efficiency (CE and power density (PD attained peak values at 10.36% and 2,236 mW/m2 respectively for 200 ppm of ANB. A further increase in ANB concentrations results in lowering of cell potential (and PD values owing to microbial inhibition at higher concentrations of toxic substrates. Cyclic voltammetry studies revealed a perfect redox reaction was taking place in the SMFC. The pH, temperature and conductivity remain 7.5-8.0, 27(±2°C and 10.6-18.2 mS/cm throughout the operation. The biodegradation pathway was studied by the gas chromatography coupled with mass spectroscopy technique, suggested the preferential cleavage of the azo bond as the initial step resulting in to aromatic amines. Thus, a combined anaerobic-aerobic process using SMFC coupled with activated sludge process can be a viable option for effective degradation of complex dye substrates along with energy (bioelectricity recovery.

  14. Impact of hyperhydration on the mortality risk in critically ill patients admitted in intensive care units: comparison between bioelectrical impedance vector analysis and cumulative fluid balance recording

    OpenAIRE

    Samoni, Sara; Vigo, Valentina; Reséndiz, Luis Ignacio Bonilla; Villa, Gianluca; De Rosa, Silvia; Nalesso, Federico; Ferrari, Fiorenza; Meola, Mario; Brendolan, Alessandra; Malacarne, Paolo; Forfori, Francesco; Bonato, Raffaele; Donadio, Carlo; Ronco, Claudio

    2016-01-01

    Background Studies have demonstrated a positive correlation between fluid overload (FO) and adverse outcomes in critically ill patients. The present study aims at defining the impact of hyperhydration on the Intensive Care Unit (ICU) mortality risk, comparing Bioelectrical Impedance Vector Analysis (BIVA) assessment with cumulative fluid balance (CFB) recording. Methods We performed a prospective, dual-centre, clinician-blinded, observational study of consecutive patients admitted to ICU with...

  15. Fat-free mass prediction equations for bioelectric impedance analysis compared to dual energy X-ray absorptiometry in obese adolescents: a validation study

    OpenAIRE

    Hofsteenge, Geesje H.; Chinapaw, Mai JM; Weijs, Peter JM

    2015-01-01

    Background In clinical practice, patient friendly methods to assess body composition in obese adolescents are needed. Therefore, the bioelectrical impedance analysis (BIA) related fat-free mass (FFM) prediction equations (FFM-BIA) were evaluated in obese adolescents (age 11–18 years) compared to FFM measured by dual-energy x-ray absorptiometry (FFM-DXA) and a new population specific FFM-BIA equation is developed. Methods After an overnight fast, the subjects attended the outpatient clinic. Af...

  16. Examination of the bioelectrical activity of the masticatory muscles during Angle’s Class II division 2 therapy with an activator

    Directory of Open Access Journals (Sweden)

    Petrović Đorđe

    2014-01-01

    Full Text Available Background/Aim. The muscles of the orofacial region have great influence on the development of dentition and occlusion formation. It is known that improper function of these muscles is one of the major etiological factors in malocclusion. A correlation between function disorders of orofacial muscle and occlusion disorders has been confirmed, as well as a correlation between the bioelectric activity of the masticatory muscles, recorded by electromyography, and bite force upon maximal voluntary contraction of these muscles. The aim of the study was to analyze the bioelectriacal activity of temporal and masseter muscles. Methods. The sample consisted of 100 subjects of both sexes, divided into the control group (n = 30 with neutral and complete dental arches, and the study group (n = 70 of patients with distal occlusion. Electromyographic measurement of bioelectric potentials in all the subjects was conducted for the examined muscles in the physiologic rest position, central mandible occlusion, and during maximal voluntary contraction of muscles and saliva swallowing, in Angle Class I and II/2 occlusal relation-ships, prior to treatment, after one year of the orthodontic treatment and after the treatment with an activator. Results. Comparing the values of thebioelectrical activity in the control and the study group before the treatment, a decreased muscle activity was established in all the three positions in the study group. After the first year of orthodontic treatment the results showed an elevation in the bioelectrical activity in both muscles. After treatment with an activator, the bioelectrical activity in both muscles in the study group was higher than before the treatment, as it is confirmed by a positive highly significant coefficient of correlation. Conclusion. In all the three measured positions of the mandible with Angle Class II/2 malocclusion, bioelectrical activity was lowest at baseline and increased during the first year of

  17. Measuring body composition in dogs using multifrequency bioelectrical impedance analysis and dual energy X-ray absorptiometry.

    Science.gov (United States)

    Rae, L S; Vankan, D M; Rand, J S; Flickinger, E A; Ward, L C

    2016-06-01

    Thirty-five healthy, neutered, mixed breed dogs were used to determine the ability of multifrequency bioelectrical impedance analysis (MFBIA) to predict accurately fat-free mass (FFM) in dogs using dual energy X-ray absorptiometry (DXA)-measured FFM as reference. A second aim was to compare MFBIA predictions with morphometric predictions. MFBIA-based predictors provided an accurate measure of FFM, within 1.5% when compared to DXA-derived FFM, in normal weight dogs. FFM estimates were most highly correlated with DXA-measured FFM when the prediction equation included resistance quotient, bodyweight, and body condition score. At the population level, the inclusion of impedance as a predictor variable did not add substantially to the predictive power achieved with morphometric variables alone; in individual dogs, impedance predictors were more valuable than morphometric predictors. These results indicate that, following further validation, MFBIA could provide a useful tool in clinical practice to objectively measure FFM in canine patients and help improve compliance with prevention and treatment programs for obesity in dogs.

  18. Extensions to a manifold learning framework for time-series analysis on dynamic manifolds in bioelectric signals

    Science.gov (United States)

    Erem, Burak; Martinez Orellana, Ramon; Hyde, Damon E.; Peters, Jurriaan M.; Duffy, Frank H.; Stovicek, Petr; Warfield, Simon K.; MacLeod, Rob S.; Tadmor, Gilead; Brooks, Dana H.

    2016-04-01

    This paper addresses the challenge of extracting meaningful information from measured bioelectric signals generated by complex, large scale physiological systems such as the brain or the heart. We focus on a combination of the well-known Laplacian eigenmaps machine learning approach with dynamical systems ideas to analyze emergent dynamic behaviors. The method reconstructs the abstract dynamical system phase-space geometry of the embedded measurements and tracks changes in physiological conditions or activities through changes in that geometry. It is geared to extract information from the joint behavior of time traces obtained from large sensor arrays, such as those used in multiple-electrode ECG and EEG, and explore the geometrical structure of the low dimensional embedding of moving time windows of those joint snapshots. Our main contribution is a method for mapping vectors from the phase space to the data domain. We present cases to evaluate the methods, including a synthetic example using the chaotic Lorenz system, several sets of cardiac measurements from both canine and human hearts, and measurements from a human brain.

  19. Extensions to a manifold learning framework for time-series analysis on dynamic manifolds in bioelectric signals.

    Science.gov (United States)

    Erem, Burak; Martinez Orellana, Ramon; Hyde, Damon E; Peters, Jurriaan M; Duffy, Frank H; Stovicek, Petr; Warfield, Simon K; MacLeod, Rob S; Tadmor, Gilead; Brooks, Dana H

    2016-04-01

    This paper addresses the challenge of extracting meaningful information from measured bioelectric signals generated by complex, large scale physiological systems such as the brain or the heart. We focus on a combination of the well-known Laplacian eigenmaps machine learning approach with dynamical systems ideas to analyze emergent dynamic behaviors. The method reconstructs the abstract dynamical system phase-space geometry of the embedded measurements and tracks changes in physiological conditions or activities through changes in that geometry. It is geared to extract information from the joint behavior of time traces obtained from large sensor arrays, such as those used in multiple-electrode ECG and EEG, and explore the geometrical structure of the low dimensional embedding of moving time windows of those joint snapshots. Our main contribution is a method for mapping vectors from the phase space to the data domain. We present cases to evaluate the methods, including a synthetic example using the chaotic Lorenz system, several sets of cardiac measurements from both canine and human hearts, and measurements from a human brain. PMID:27176304

  20. Influence of Posture and Frequency Modes in Total Body Water Estimation Using Bioelectrical Impedance Spectroscopy in Boys and Adult Males

    Directory of Open Access Journals (Sweden)

    Masaharu Kagawa

    2014-05-01

    Full Text Available The aim of the study was to examine differences in total body water (TBW measured using single-frequency (SF and multi-frequency (MF modes of bioelectrical impedance spectroscopy (BIS in children and adults measured in different postures using the deuterium (2H dilution technique as the reference. Twenty-three boys and 26 adult males underwent assessment of TBW using the dilution technique and BIS measured in supine and standing positions using two frequencies of the SF mode (50 kHz and 100 kHz and the MF mode. While TBW estimated from the MF mode was comparable, extra-cellular fluid (ECF and intra-cellular fluid (ICF values differed significantly (p < 0.01 between the different postures in both groups. In addition, while estimated TBW in adult males using the MF mode was significantly (p < 0.01 greater than the result from the dilution technique, TBW estimated using the SF mode and prediction equation was significantly (p < 0.01 lower in boys. Measurement posture may not affect estimation of TBW in boys and adult males, however, body fluid shifts may still occur. In addition, technical factors, including selection of prediction equation, may be important when TBW is estimated from measured impedance.

  1. GHG emission factors for bioelectricity, biomethane, and bioethanol quantified for 24 biomass substrates with consequential life-cycle assessment.

    Science.gov (United States)

    Tonini, Davide; Hamelin, Lorie; Alvarado-Morales, Merlin; Astrup, Thomas Fruergaard

    2016-05-01

    Greenhouse gas (GHG) emission savings from biofuels dramatically depend upon the source of energy displaced and the effects induced outside the energy sector, for instance land-use changes (LUC). Using consequential life-cycle assessment and including LUC effects, this study provides GHG emission factors (EFs) for bioelectricity, biomethane, and bioethanol produced from twenty-four biomasses (from dedicated crops to residues of different origin) under a fossil and a non-fossil energy system. Accounting for numerous variations in the pathways, a total of 554 GHG EFs were quantified. The results showed that, important GHG savings were obtained with residues and seaweed, both under fossil and non-fossil energy systems. For high-yield perennial crops (e.g. willow and Miscanthus), GHG savings were achieved only under fossil energy systems. Biofuels from annual crops and residues that are today used in the feed sector should be discouraged, as LUC GHG emissions exceeded any GHG savings from displacing conventional energy sources. PMID:26938807

  2. The investigation of the some body parameters of obese and (obese+diabetes) patients with using bioelectrical impedance analysis techniques

    Science.gov (United States)

    Yerlikaya, Emrah; Karageçili, Hasan; Aydin, Ruken Zeynep

    2016-04-01

    Obesity is a key risk for the development of hyperglycemia, hypertension, hyperlipidemia, insulin resistance and is totally referred to as the metabolic disorders. Diabetes mellitus, a metabolic disorder, is related with hyperglycemia, altered metabolism of lipids, carbohydrates and proteins. The minimum defining characteristic feature to identify diabetes mellitus is chronic and substantiated elevation of circulating glucose concentration. In this study, it is aimed to determine the body composition analyze of obese and (obese+diabetes) patients.We studied the datas taken from three independent groups with the body composition analyzer instrument. The body composition analyzer calculates body parameters, such as body fat ratio, body fat mass, fat free mass, estimated muscle mass, and base metabolic rate on the basis of data obtained by Dual Energy X-ray Absorptiometry using Bioelectrical Impedance Analysis. All patients and healthy subjects applied to Siirt University Medico and their datas were taken. The Statistical Package for Social Sciences version 21 was used for descriptive data analysis. When we compared and analyzed three groups datas, we found statistically significant difference between obese, (obese+diabetes) and control groups values. Anova test and tukey test are used to analyze the difference between groups and to do multiple comparisons. T test is also used to analyze the difference between genders. We observed the statistically significant difference in age and mineral amount pbody mass index, water percentage, protein mass percentage, mineral percentage p<0.05, significant statistically difference were observed. This difference especially may result of a sedentary lifestyle.

  3. Measuring body composition in dogs using multifrequency bioelectrical impedance analysis and dual energy X-ray absorptiometry.

    Science.gov (United States)

    Rae, L S; Vankan, D M; Rand, J S; Flickinger, E A; Ward, L C

    2016-06-01

    Thirty-five healthy, neutered, mixed breed dogs were used to determine the ability of multifrequency bioelectrical impedance analysis (MFBIA) to predict accurately fat-free mass (FFM) in dogs using dual energy X-ray absorptiometry (DXA)-measured FFM as reference. A second aim was to compare MFBIA predictions with morphometric predictions. MFBIA-based predictors provided an accurate measure of FFM, within 1.5% when compared to DXA-derived FFM, in normal weight dogs. FFM estimates were most highly correlated with DXA-measured FFM when the prediction equation included resistance quotient, bodyweight, and body condition score. At the population level, the inclusion of impedance as a predictor variable did not add substantially to the predictive power achieved with morphometric variables alone; in individual dogs, impedance predictors were more valuable than morphometric predictors. These results indicate that, following further validation, MFBIA could provide a useful tool in clinical practice to objectively measure FFM in canine patients and help improve compliance with prevention and treatment programs for obesity in dogs. PMID:27256027

  4. [Approaches to reduce the retroaction of long-term monitoring of bioelectric events in ergonomic field studies (author's transl)].

    Science.gov (United States)

    Zipp, P; Faber, S

    1979-10-01

    When monitoring bioelectric signals the surface electrodes can cause a retroaction on the subject thereby introducing an error of measurement. There are two types of retroaction: physical and psycho-physiological. A physical retroaction due to the hydration process of the skin occurs if 'wet' electrodes are used for the recording of the skin conductance level (SCL) causing a continuous drift of the SCL and a decrease in sensitivity to SCL changes. Therefore a dry electrode was developed with improved performance: It exhibits less sensitivity to motion, is not subject to polarization, and features better SCL long-term stability. When recording the electrocardiogram or the electromyogram a psychophysiological retroaction occurs due to the annoyance caused by the skin-irritating abrading techniques in order to decrease the skin impedance and reduce the motion artifact. In an attempt to abandon the skin preparation whenever permissible without sacrificing the measurement accuracy a performance estimation procedure was developed. Basing on the information on the signal frequency content, the electrode contact area, the required accuracy of measurement and the amplifier input impedance a decision on the necessity of skin preparation is made. Moreover, the results of a study are reported investigating the reduction of motion artifacts by means of electrode design and appropriate electrode jelly formulation.

  5. 器官形态发生探索Ⅰ:生物电与形态发生%Exploration of organ morphogenesis Ⅰ:Bioelectricity and morphogenesis

    Institute of Scientific and Technical Information of China (English)

    赵海平; 刘振; 陈广信; 李春义

    2015-01-01

    Summary Morphogenesis is a biological process that involves the shape development and pattern maintenance of an organism . Morphogenetic information is needed for morphogenetic primordial developing to construct an appropriate three‐dimension (3D) structure , which includes three aspects :positional information , prepatterning information , and epigenetic information . The essence and mechanism of morphogenetic information is the primary condition to understand morphogenesis . This paper reviews the latest research progress of morphogenetic field , bioelectricity and organ morphogenesis . Mechanism of organ morphogenesis has not been well understood in life science field . Advances in molecular biology were expected to solve this mystery , but proved to be a failure . Interestingly , recent study showed that organ morphogenesis was regulated by bioelectricity at multiple levels on lower animals , for example:1) Artificially setting the resting potential in embryonic frog cells can lead to eye formation at any part of amphibian body ;2) bioelectricity can regulate regeneration of tail and ectopic limb formation in Xenopus tadpoles ;3) bioelectricity determines regeneration pattern of amputated planaria fragments on whether head or tail . Therefore , organ fate was obviously determined by bioelectric state of morphogenetic primordia . Bioelectricity is the essence of organ morphogenetic information , which is a landmark advance in this field that the bioelectricity encodes organ morphogenesis . It is an inspiration that electric is used as a signal code in communication for understanding work mechanism of bioelectric code . For example , Morse alphabet and binary , which consist of electrical signal , are used in telegram system and computer system respectively . Nowadays , 3D structures can be made by 3D printer , and the machine can execute commands encoded by binary . The physical process of bioelectricity encoding organ morphogenesis in animal bodies is

  6. Foot-to-foot bioelectrical impedance accurately tracks direction of adiposity change in overweight and obese 7- to 13-year-old children.

    Science.gov (United States)

    Kasvis, Popi; Cohen, Tamara R; Loiselle, Sarah-Ève; Kim, Nicolas; Hazell, Tom J; Vanstone, Catherine A; Rodd, Celia; Plourde, Hugues; Weiler, Hope A

    2015-03-01

    Body composition measurements are valuable when evaluating pediatric obesity interventions. We hypothesized that foot-to-foot bioelectrical impedance analysis (BIA) will accurately track the direction of adiposity change, but not magnitude, in part due to differences in fat patterning. The purposes of this study were to examine the accuracy of body composition measurements of overweight and obese children over time using dual-energy x-ray absorptiometry (DXA) and BIA and to determine if BIA accuracy was affected by fat patterning. Eighty-nine overweight or obese children (48 girls, 41 boys, age 7-13 years) participating in a randomized controlled trial providing a family-centered, lifestyle intervention, underwent DXA and BIA measurements every 3 months. Bland-Altman plots showed a poor level of agreement between devices for baseline percent body fat (%BF; mean, 0.398%; +2SD, 8.685%; -2SD, -7.889%). There was overall agreement between DXA and BIA in the direction of change over time for %BF (difference between visits 3 and 1: DXA -0.8 ± 0.5%, BIA -0.7 ± 0.5%; P = 1.000) and fat mass (FM; difference between visits 3 and 1: DXA 0.7 ± 0.5 kg, BIA 0.6 ± 0.5 kg; P = 1.000). Bioelectrical impedance analysis measurements of %BF and FM at baseline were significantly different in those with android and gynoid fat (%BF: 35.9% ± 1.4%, 32.2% ± 1.4%, P < .003; FM: 20.1 ± 0.8 kg, 18.4 ± 0.8, P < .013). Bioelectrical impedance analysis accurately reports the direction of change in FM and FFM in overweight and obese children; inaccuracy in the magnitude of BIA measurements may be a result of fat patterning differences.

  7. Reliability of Calf Bioelectrical Impedance Spectroscopy and Magnetic-Resonance-Imaging-Acquired Skeletal Muscle Hydration Measures in Healthy People

    Directory of Open Access Journals (Sweden)

    Anuradha Sawant

    2013-01-01

    Full Text Available Purpose. The purpose of this study was to investigate the test-retest reliability, relative variability, and agreement between calf bioelectrical impedance-spectroscopy (cBIS acquired extracellular fluid (ECF, intracellular fluid (ICF, total water and the ratio of ECF : ICF, magnetic-resonance-imaging (MRI acquired transverse relaxation times (T2, and apparent diffusion coefficient (ADC of calf muscles of the same segment in healthy individuals. Methods. Muscle hydration measures were collected in 32 healthy individuals on two occasions and analyzed by a single rater. On both occasions, MRI measures were collected from tibialis anterior (TA, medial (MG, and lateral gastrocnemius (LG and soleus muscles following the cBIS data acquired using XiTRON Hydra 4200 BIS device. The intraclass correlation coefficients (ICC2,1, coefficient of variation (CV, and agreement between MRI and cBIS data were also calculated. Results. ICC2,1 values for cBIS, T2, and ADC ranged from 0.56 to 0.92, 0.96 to 0.99, and 0.05 to 0.56, respectively. Relative variability between measures (CV ranged from 14.6 to 25.6% for the cBIS data and 4.2 to 10.0% for the MRI-acquired data. The ratio of ECF : ICF could significantly predict T2 of TA and soleus muscles. Conclusion. MRI-acquired measures of T2 had the highest test-retest reliability of muscle hydration with the least error and variation on repeated testing. Hence, T2 of a muscle is the most reliable and stable outcome measure for evaluating individual muscle hydration.

  8. Comparison of Standing Posture Bioelectrical Impedance Analysis with DXA for Body Composition in a Large, Healthy Chinese Population

    Science.gov (United States)

    Chen, Kuen-Tsann; Chen, Yu-Yawn; Wang, Chia-Wei; Chuang, Chih-Lin; Chiang, Li-Ming; Lai, Chung-Liang; Lu, Hsueh-Kuan; Dwyer, Gregory B.; Chao, Shu-Ping; Shih, Ming-Kuei; Hsieh, Kuen-Chang

    2016-01-01

    Bioelectrical impedance analysis (BIA) is a common method for assessing body composition in research and clinical trials. BIA is convenient but when compared with other reference methods, the results have been inconclusive. The level of obesity degree in subjects is considered to be an important factor affecting the accuracy of the measurements. A total of 711 participants were recruited in Taiwan and were sub-grouped by gender and levels of adiposity. Regression analysis and Bland-Altman analysis were used to evaluate the agreement of the measured body fat percentage (BF%) between BIA and DXA. The BF% measured by the DXA and BIA methods (Tanita BC-418) were expressed as BF%DXA and BF%BIA8, respectively. A one-way ANOVA was used to test the differences in BF% measurements by gender and levels of adiposity. The estimated BF%BIA8 and BF%DXA in the all subjects, male and female groups were all highly correlated (r = 0.934, 0.901, 0.916, all P< 0.001). The average estimated BF%BIA8 (22.54 ± 9.48%) was significantly lower than the average BF%DXA (26.26 ± 11.18%). The BF%BIA8 was overestimated in the male subgroup (BF%DXA< 15%), compared to BF%DXA by 0.45%, respectively. In the other subgroups, the BF%BIA8 values were all underestimated. Standing BIA estimating body fat percentage in Chinese participants have a high correlation, but underestimated on normal and high obesity degree in both male and female subjects. PMID:27467065

  9. Evaluation of a foot-to-foot bioelectrical impedance analyser in highly active, moderately active and less active young men.

    Science.gov (United States)

    Swartz, Ann M; Swartz, Ann M; Jeremy Evans, M; King, George A; Thompson, Dixie L

    2002-08-01

    The Tanita TBF-305 (Tanita Corp., Tokyo, Japan) is a commercially available foot-to-foot bioelectrical impedance analysis (BIA) system. The manufacturer-supplied equations incorporate gender, mass, height, activity category and a measured impedance value to determine % body fat (BF). The purpose of the present study was to determine whether the manufacturer-supplied 'adult' and 'athlete' equations provided an accurate estimate of % BF for a group of young men with varying activity levels. Fifty-seven men (18-35 years old) were categorized into the following groups: (1) highly active (HA) (> or = 10.0 h aerobic activity/week); (2) moderately active (MA) (2.5-10.0 h aerobic activity/week); (3) less active (LA) (aerobic activity/week). The % BF was measured using the BIA 'athlete' and 'adult' modes. After BIA measurements, residual volume was measured and hydrostatic weighing (HW) was performed. The amount of activity performed by each group was significantly different (P<0.001). No significant differences were found between the % BF determined by the 'athlete' mode and HW for HA (P=0.309) and MA (P=0.091). However, a significant difference was found for LA (P=0.001). The % BF determined by the 'adult' mode and HW was not different for LA (P=0.395), but was significantly different for MA (P<0.001) and HA (P<0.001). The choice of activity mode on the foot-to-foot BIA significantly alters prediction of % BF. With careful selection of activity mode, there was no statistical difference between % BF determined by HW and the BIA, but the range of individual error scores was large. PMID:12144724

  10. The investigation of the some body parameters of obese and (obese+diabetes) patients with using bioelectrical impedance analysis techniques

    Science.gov (United States)

    Yerlikaya, Emrah; Karageçili, Hasan; Aydin, Ruken Zeynep

    2016-04-01

    Obesity is a key risk for the development of hyperglycemia, hypertension, hyperlipidemia, insulin resistance and is totally referred to as the metabolic disorders. Diabetes mellitus, a metabolic disorder, is related with hyperglycemia, altered metabolism of lipids, carbohydrates and proteins. The minimum defining characteristic feature to identify diabetes mellitus is chronic and substantiated elevation of circulating glucose concentration. In this study, it is aimed to determine the body composition analyze of obese and (obese+diabetes) patients.We studied the datas taken from three independent groups with the body composition analyzer instrument. The body composition analyzer calculates body parameters, such as body fat ratio, body fat mass, fat free mass, estimated muscle mass, and base metabolic rate on the basis of data obtained by Dual Energy X-ray Absorptiometry using Bioelectrical Impedance Analysis. All patients and healthy subjects applied to Siirt University Medico and their datas were taken. The Statistical Package for Social Sciences version 21 was used for descriptive data analysis. When we compared and analyzed three groups datas, we found statistically significant difference between obese, (obese+diabetes) and control groups values. Anova test and tukey test are used to analyze the difference between groups and to do multiple comparisons. T test is also used to analyze the difference between genders. We observed the statistically significant difference in age and mineral amount p<0.00 between (diabetes+obese) and obese groups. Besides, when these patient groups and control group were analyzed, there were significant difference between most parameters. In terms of education level among the illiterate and university graduates; fat mass kg, fat percentage, internal lubrication, body mass index, water percentage, protein mass percentage, mineral percentage p<0.05, significant statistically difference were observed. This difference especially may result

  11. Quantitative analysis of bioelectrical potentials for the diagnosis of internal organ pathology and theoretical speculations concerning electrical circulation in the organism.

    Science.gov (United States)

    Zukauskas, G; Dapsys, K; Ilgesviciute, J; Vaitkus, P

    1988-01-01

    Over 900 experiments on dogs and 135 clinical investigations of healthy people and patients of psychiatric and cardiological departments were performed. With the aid of a 8-channel biopotential amplifier and integrator, bioelectrical potential (BEP) directly from internal organs or from various skin zones were recorded. The quantitative parameters of the BEP--their square values and the sum of the square values of BEP recorded simultaneously from several points of the organism--were measured. The effect of low (1 Hz) and high (28 GHz) frequency electrical stimulation was studied. The stimulation of spleen, liver, stomach, small intestine and corresponding acupuncture points had the greatest effect on the quantitative parameters of the BEP in stomach and small intestine. During patient investigation, the most remarkable changes of the studied parameters were noticed in the BEP recorded from the acupuncture points of the affected internal organ meridians. The existence of the common points between Eastern medicine and Western science are discussed. The analysis of the BEP quantitative parameters proves the existence of electrophysiological equilibrium parameters in the organism--bioelectrical homeostasis. The possible theories of electrical circulation in the organism and their relations with traditional acupuncture theoretical concepts are also discussed. PMID:2904209

  12. Effects of various organic carbon sources on simultaneous V(V) reduction and bioelectricity generation in single chamber microbial fuel cells.

    Science.gov (United States)

    Hao, Liting; Zhang, Baogang; Cheng, Ming; Feng, Chuanping

    2016-02-01

    Four ordinary carbon sources affecting V(V) reduction and bioelectricity generation in single chamber microbial fuel cells (MFCs) were investigated. Acetate supported highest maximum power density of 589.1mW/m(2), with highest V(V) removal efficiency of 77.6% during 12h operation, compared with glucose, citrate and soluble starch. Exorbitant initial V(V) concentration led to lower V(V) removal efficiencies and power outputs. Extra addition of organics had little effect on the improvement of MFCs performance. V(V) reduction and bioelectricity generation were enhanced and then suppressed by the increase of conductivity. The larger the external resistance, the higher the V(V) removal efficiencies and voltage outputs. High-throughput 16S rRNA gene pyrosequencing analysis implied the accumulation of Enterobacter which had the capabilities of V(V) reduction, electrochemical activity and fermentation, accompanied with other functional species as Pseudomonas, Spirochaeta, Sedimentibacter and Dysgonomonas. This study steps forward to remediate V(V) contaminated environment based on MFC technology.

  13. Performance of Two Bioelectrical Impedance Analyses in the Diagnosis of Overweight and Obesity in Children and Adolescents: The FUPRECOL Study

    Directory of Open Access Journals (Sweden)

    Robinson Ramírez-Vélez

    2016-10-01

    Full Text Available This study aimed to determine thresholds for percentage of body fat (BF% corresponding to the cut-off values for overweight/obesity as recommended by the International Obesity Task Force (IOTF, using two bioelectrical impedance analyzers (BIA, and described the likelihood of increased cardiometabolic risk in our cohort defined by the IOTF and BF% status. Participants included 1165 children and adolescents (54.9% girls from Bogotá (Colombia. Body mass index (BMI was calculated from height and weight. BF% of each youth was assessed first using the Tanita BC-418® followed by a Tanita BF-689®. The sensitivity and specificity of both devices and their ability to correctly classify children as overweight/obesity (≥2 standard deviation, as defined by IOTF, was investigated using receiver operating characteristic (ROC by sex and age groups (9–11, 12–14, and 13–17 years old; Area under curve (AUC values were also reported. For girls, the optimal BF% threshold for classifying into overweight/obesity was found to be between 25.2 and 28.5 (AUC = 0.91–0.97 and 23.9 to 26.6 (AUC = 0.90–0.99 for Tanita BC-418® and Tanita BF-689®, respectively. For boys, the optimal threshold was between 16.5 and 21.1 (AUC = 0.93–0.96 and 15.8 to 20.6 (AUC = 0.92–0.94 by Tanita BC-418® and Tanita BF-689®, respectively. All AUC values for ROC curves were statistically significant and there were no differences between AUC values measured by both BIA devices. The BF% values associated with the IOTF-recommended BMI cut-off for overweight/obesity may require age- and sex-specific threshold values in Colombian children and adolescents aged 9–17 years and could be used as a surrogate method to identify individuals at risk of excess adiposity.

  14. Performance of Two Bioelectrical Impedance Analyses in the Diagnosis of Overweight and Obesity in Children and Adolescents: The FUPRECOL Study

    Science.gov (United States)

    Ramírez-Vélez, Robinson; Correa-Bautista, Jorge Enrique; Martínez-Torres, Javier; González-Ruíz, Katherine; González-Jiménez, Emilio; Schmidt-RioValle, Jacqueline; Garcia-Hermoso, Antonio

    2016-01-01

    This study aimed to determine thresholds for percentage of body fat (BF%) corresponding to the cut-off values for overweight/obesity as recommended by the International Obesity Task Force (IOTF), using two bioelectrical impedance analyzers (BIA), and described the likelihood of increased cardiometabolic risk in our cohort defined by the IOTF and BF% status. Participants included 1165 children and adolescents (54.9% girls) from Bogotá (Colombia). Body mass index (BMI) was calculated from height and weight. BF% of each youth was assessed first using the Tanita BC-418® followed by a Tanita BF-689®. The sensitivity and specificity of both devices and their ability to correctly classify children as overweight/obesity (≥2 standard deviation), as defined by IOTF, was investigated using receiver operating characteristic (ROC) by sex and age groups (9–11, 12–14, and 13–17 years old); Area under curve (AUC) values were also reported. For girls, the optimal BF% threshold for classifying into overweight/obesity was found to be between 25.2 and 28.5 (AUC = 0.91–0.97) and 23.9 to 26.6 (AUC = 0.90–0.99) for Tanita BC-418® and Tanita BF-689®, respectively. For boys, the optimal threshold was between 16.5 and 21.1 (AUC = 0.93–0.96) and 15.8 to 20.6 (AUC = 0.92–0.94) by Tanita BC-418® and Tanita BF-689®, respectively. All AUC values for ROC curves were statistically significant and there were no differences between AUC values measured by both BIA devices. The BF% values associated with the IOTF-recommended BMI cut-off for overweight/obesity may require age- and sex-specific threshold values in Colombian children and adolescents aged 9–17 years and could be used as a surrogate method to identify individuals at risk of excess adiposity. PMID:27782039

  15. Assessment of bioelectrical activity of synergistic muscles during pelvic floor muscles activation in postmenopausal women with and without stress urinary incontinence: a preliminary observational study

    Directory of Open Access Journals (Sweden)

    Ptaszkowski K

    2015-09-01

    Full Text Available Kuba Ptaszkowski,1 Małgorzata Paprocka-Borowicz,2 Lucyna Słupska,2 Janusz Bartnicki,1,3 Robert Dymarek,4 Joanna Rosińczuk,4 Jerzy Heimrath,5 Janusz Dembowski,6 Romuald Zdrojowy6 1Department of Obstetrics, 2Department of Clinical Biomechanics and Physiotherapy in Motor System Disorders, Wroclaw Medical University, Wroclaw, Poland; 3Department of Obstetrics and Gynecology, Health Center Bitterfeld/Wolfen gGmbH, Bitterfeld-Wolfen, Germany; 4Department of Nervous System Diseases, 5Department of Gynaecology and Obstetrics, Faculty of Health Science, 6Department and Clinic of Urology, Faculty of Postgraduate Medical Training, Wroclaw Medical University, Wroclaw, Poland Objective: Muscles such as adductor magnus (AM, gluteus maximus (GM, rectus abdominis (RA, and abdominal external and internal oblique muscles are considered to play an important role in the treatment of stress urinary incontinence (SUI, and the relationship between contraction of these muscles and pelvic floor muscles (PFM has been established in previous studies. Synergistic muscle activation intensifies a woman’s ability to contract the PFM. In some cases, even for continent women, it is not possible to fully contract their PFM without involving the synergistic muscles. The primary aim of this study was to assess the surface electromyographic activity of synergistic muscles to PFM (SPFM during resting and functional PFM activation in postmenopausal women with and without SUI.Materials and methods: This study was a preliminary, prospective, cross-sectional observational study and included volunteers and patients who visited the Department and Clinic of Urology, University Hospital in Wroclaw, Poland. Forty-two patients participated in the study and were screened for eligibility criteria. Thirty participants satisfied the criteria and were categorized into two groups: women with SUI (n=16 and continent women (n=14. The bioelectrical activity of PFM and SPFM (AM, RA, GM was

  16. The influence of high-intensity radiation on the functional status of monkey brain. Postirradiation changes in the intracentral coordination of bioelectric processes in the brain

    International Nuclear Information System (INIS)

    In experiments with Macaca fascicularis exposed to high-energy electrons (45 Gy, 6.5 Gy/s) revealed were early changes in the coherent spectrum of EEG semihemisphere leads. These changes were displayed by the increased interrelation between slow-wave fluctuations and decreased coherence within the mid- and high-frequency EEG-rhythms band. The relationship was noted between the changes observed and the clinical symptoms features of early radiation response as weel as the dynamics of the CNS functions of exposed animals. Postirradiation changes in the intracellular bioelectric interaction are considered as one of the manifestations of the systemic response of the brain to the harmful effect of radiation

  17. Land use changes, greenhouse gas emissions and fossil fuel substitution of biofuels compared to bioelectricity production for electric cars in Austria

    International Nuclear Information System (INIS)

    Bioenergy is one way of achieving the indicative target of 10% renewable energy in the transportation sector outlined in the EU Directive 2009/28/EC. This article assesses the consequences of increasing the use of bioenergy for road transportation on land use, greenhouse gas (GHG) emissions, and fossil fuel substitution. Different technologies, including first and second generation fuels and electric cars fuelled by bioelectricity are assessed in relation to existing bioenergy uses for heat and power production. The article applies a spatially explicit energy system model that is coupled with a land use optimization model to allow assessing impacts of increased biomass utilization for energy production on land use in agriculture and forest wood harvests. Uncertainty is explicitly assessed with Monte-Carlo simulations of model parameters. Results indicate that electric mobility could save GHG emissions without causing a significant increase in domestic land use for energy crop production. Costs of electric cars are still prohibitive. Second generation biofuels are more effective in producing fuels than first generation ethanol. However, competition with power and heat production from ligno-cellulosic feedstock causes an increase in GHG emissions when introducing second generation fuels in comparison to a baseline scenario. -- Highlights: → Assessment of land use and greenhouse gas emissions (GHG) of renewable transportation options. → Optimization model compares 1st and 2nd generation biofuels and bioelectricity for electric cars. → Use of agricultural land for 1st generation ethanol production is highest among options. → 2nd generation fuel production deviates resources from efficient heat and power production. → Electric cars use less land and save more GHG emissions than other options but costs are prohibitive.

  18. Are Ethnic and Gender Specific Equations Needed to Derive Fat Free Mass from Bioelectrical Impedance in Children of South Asian, Black African-Caribbean and White European Origin? Results of the Assessment of Body Composition in Children Study

    OpenAIRE

    Nightingale, Claire M; Rudnicka, Alicja R; Owen, Christopher G; Donin, Angela S.; Newton, Sian L.; Furness, Cheryl A.; Emma L Howard; Gillings, Rachel D.; Jonathan C K Wells; Cook, Derek G.; Whincup, Peter H.

    2013-01-01

    BACKGROUND: Bioelectrical impedance analysis (BIA) is a potentially valuable method for assessing lean mass and body fat levels in children from different ethnic groups. We examined the need for ethnic- and gender-specific equations for estimating fat free mass (FFM) from BIA in children from different ethnic groups and examined their effects on the assessment of ethnic differences in body fat. METHODS: Cross-sectional study of children aged 8-10 years in London Primary schools including 325 ...

  19. 电致生物效应高压脉冲源控制系统设计%Design of high voltage pulse generator for bioelectrical effect

    Institute of Scientific and Technical Information of China (English)

    马勋; 任青毅; 贾兴

    2011-01-01

    In order to improve the output accuracy and reliahility of bioelectrical effect high pulse generator running continuously,a bioelectrical effect high voltage pulse generator control system based on embedded real time operating system Small RTOS51 was designed. It used NEC8254-2 to realize adjustahle PWM output of frequency and duty cycle, applied MAX526 and MAX197 to achieve D/A and A/D function. composing the high voltage pulse generator output control and feedback loop, and presented an improved sampling signal median filter algorithm. Compared to traditional algorithm, this algorithm has higher sensihility, based on RTOS programmer , it improves the reliahility of system. Experimental results show that the output accuracy of high voltage pulse generator is up to 0.1% .%为了提高电致生物效应高压脉冲源连续运行时的输出精度及可靠性,设计了一种基于嵌入式实时操作系统Small RTOS51的电致生物效应高压脉冲源控制系统.采用NEC8254-2低成本地实现频率、占空比可调PWM输出,以MAX526,MAX197分别实现D/A,A/D功能,构成高压脉冲源输出控制与反馈回路,并提出了一种改进的采样信号中位值滤波算法.与传统中住值滤波算法相比,该算法具有更高灵敏度,基于RTOS的程序设计,提高了系统的可靠性.实验结果表明:高压脉冲源在连续运行务件下输出精度稳定达到0.1%.

  20. Evaluation of dairy industry wastewater treatment and simultaneous bioelectricity generation in a catalyst-less and mediator-less membrane microbial fuel cell

    Directory of Open Access Journals (Sweden)

    Hossein Jafari Mansoorian

    2016-01-01

    Full Text Available Increased human activity and consumption of natural energy resources have led to decline in fossil fuel. These current methods of energy production are not compatible with the environment. In this study catalyst-less and mediator-less membrane microbial fuel cell (CAML-MMFC represents a new method for simultaneous dairy industry wastewater treatment and bioelectricity generation. The CAML-MMFC used was designed as two chambered that included an anaerobic anode and aerobic cathode compartment and was separated from each other by a proton exchange membrane. The anode and cathode electrodes were made from graphite plate. Current intensity, power density and voltage produced from wastewater as fuel were measured and the effluent from the anode compartment was examined to evaluate pollutant decrease. The maximum current intensity and power density produced were respectively 3.74 mA and 621.13 mW/m2 on the anode surface, at OLR equal to 53.22 kgCOD/m3 d and at the external resistance of 1 k Ω. The maximum voltage produced was 0.856 V at OLR equal to 53.22 kgCOD/m3 d and at temperature 35oC. The maximum coulombic efficiency of 37.16% was achieved at OLR equal to 17.74 kgCOD/m3 d. The HRT was examined as a factor influencing the power generation and when it was 5 day, maximum voltage and power density were obtained. The maximum removal efficiency of COD, BOD5, NH3, NH4+, dissolved phosphorus, phosphorus in suspended solids, SO42−, TSS, and VSS was respectively achieved at 90.46%, 81.72%, 73.22%, 69.43%, 31.18%, 72.45%, 39.43%, 70.17% and 64.6%. The results showed that generating bioelectricity and dairy industry wastewater treatment by CAML-MMFC are a good alternative for producing energy and treating wastewater at the same time.

  1. Treatment of colour industry wastewaters with concomitant bioelectricity production in a sequential stacked mono-chamber microbial fuel cells-aerobic system.

    Science.gov (United States)

    Fernando, Eustace; Keshavarz, Taj; Kyazze, Godfrey; Fonseka, Keerthi

    2016-01-01

    The scalability of any microbial fuel cell (MFC)-based system is of vital importance if it is to be utilized for potential field applications. In this study, an integrated MFC-aerobic bioreactor system was investigated for its scalability with the purpose of treating a simulated dye wastewater and industrial wastewaters originated from textile dyebaths and leather tanning. The influent containing real wastewater was fed into the reactor in continuous mode at ambient temperature. Three MFC units were integrated to act in unison as a single module for wastewater treatment and a continuously stirred aerobic bioreactor operating downstream to the MFC module was installed in order to ensure more complete degradation of colouring agents found in the wastewater. Total colour removal in the final effluent exceeded 90% in all experiments where both synthetic (AO-7 containing) and real wastewater were used as the influent feed. The chemical oxygen demand reduction also exceeded 80% in all experiments under the same conditions. The MFC modules connected in parallel configuration allowed obtaining higher current densities than that can be obtained from a single MFC unit. The maximum current density of the MFC stack reached 1150 mA m(-2) when connected in a parallel configuration. The outcome of this work implies that suitably up-scaled MFC-aerobic integrated bioprocesses could be used for colour industry wastewater treatment under industrially relevant conditions with possible prospects of bioelectricity generation. PMID:26212183

  2. BODY COMPOSITION OF YOUNG PEOPLE AGED 17-18 YEARS, PRACTICING AND NOT PRACTICING SWIMMING, WITH THE USE OF THE BIOELECTRICAL IMPEDANCE METHOD

    Directory of Open Access Journals (Sweden)

    Jendrysek Marek

    2015-11-01

    Full Text Available Purpose: Body composition evaluation of youth aged 17-18 of a different physical activity with the help of bioelectric impedance method. Material and Methods: 18 boys practicing swimming and 19 boys not practicing it took part in the study, making up a control group. Height, weight, BMI, lean body mass, the content of fat and water, Rohr factor were evaluated. Non-parametric Mann-Whitney test has been used to evaluate the differences in the range of the tissue components between the two groups. Results: Statistically significant differences were found on the p<0,05 level in % fat content. Mean body weight in experimental group was 71.5 kg, while in control group it was 69.4 kg. Minimum and maximum weight in group of swimming-practicing persons was: 56.6-92.2 kg. Increased body weight in the group of swimmers can result from greater amount of active tissue in this group compared with persons of low physical activity. Proportionally, it amounted to 64.3 kg and 61.3 kg. In the tested groups, minimal and maximal values of amount of active tissue proportionately amounted to: 54.1-78 and 49.5-72,3 kg. Conclusions: Physical activity modifies body composition. Active lifestyle is one of the methods for prevention of overweight and obesity.

  3. The effect of algae species on the bioelectricity and biodiesel generation through open-air cathode microbial fuel cell with kitchen waste anaerobically digested effluent as substrate.

    Science.gov (United States)

    Hou, Qingjie; Nie, Changliang; Pei, Haiyan; Hu, Wenrong; Jiang, Liqun; Yang, Zhigang

    2016-10-01

    Five strains algae (Golenkinia sp. SDEC-16, Chlorella vulgaris, Selenastrum capricornutum, Scenedesmus SDEC-8 and Scenedesmus SDEC-13) were screened as an effective way to promote recover electricity from MFC for kitchen waste anaerobically digested effluent (KWADE) treatment. The highest OCV, power density, biomass concentration and total lipid content were obtained with Golenkinia sp. SDEC-16 as the co-inoculum, which were 170mV, 6255mWm(-3), 325mgL(-1) and 38%, respectively. Characteristics of the organics in KWADE were analyzed, and the result showed that the hydrophilic and acidic fractions were more readily degraded, compared to the neutral fractions during the operation. Maximum COD and TN removal efficiency were 43.59% and 37.39% when inoculated with Golenkinia sp. SDEC-16, which were roughly 3.22 and 3.04 times higher than that of S. capricornutum. This study demonstrated that Golenkinia sp. SDEC-16 was a promising species for bioelectricity generation, lipid production and KWADE treatment. PMID:27441827

  4. Wearable Multi-Frequency and Multi-Segment Bioelectrical Impedance Spectroscopy for Unobtrusively Tracking Body Fluid Shifts during Physical Activity in Real-Field Applications: A Preliminary Study

    Directory of Open Access Journals (Sweden)

    Federica Villa

    2016-05-01

    Full Text Available Bioelectrical Impedance Spectroscopy (BIS allows assessing the composition of body districts noninvasively and quickly, potentially providing important physiological/clinical information. However, neither portable commercial instruments nor more advanced wearable prototypes simultaneously satisfy the demanding needs of unobtrusively tracking body fluid shifts in different segments simultaneously, over a broad frequency range, for long periods and with high measurements rate. These needs are often required to evaluate exercise tests in sports or rehabilitation medicine, or to assess gravitational stresses in aerospace medicine. Therefore, the aim of this work is to present a new wearable prototype for monitoring multi-segment and multi-frequency BIS unobtrusively over long periods. Our prototype guarantees low weight, small size and low power consumption. An analog board with current-injecting and voltage-sensing electrodes across three body segments interfaces a digital board that generates square-wave current stimuli and computes impedance at 10 frequencies from 1 to 796 kHz. To evaluate the information derivable from our device, we monitored the BIS of three body segments in a volunteer before, during and after physical exercise and postural shift. We show that it can describe the dynamics of exercise-induced changes and the effect of a sit-to-stand maneuver in active and inactive muscular districts separately and simultaneously.

  5. Study of Noninvasive Intracranial Pressure Monitoring by Bioelectric Impedance Method%生物电阻抗法无创监护颅内压研究

    Institute of Scientific and Technical Information of China (English)

    肖贵遐; 刘国庆; 彭玉平; 朱代谟

    2001-01-01

    The changes of intracranial components and corr esponding brain impedan ce were analyzed while intracranial pressure was increasing, and the relation of intr acranial pressure pulse wave and brain impedance pulse wave were discussed. A theory of noninvasive intracranial pressure monitoring by bioelectric impedance was put forward. The result of primary experiment suggested that the theory be feasible.%分析了在颅内压增高的过程中,颅内容 物的变化及相应的脑阻抗的变化情况 ,同时讨论了在颅内压升高以后颅内压脉冲波和脑阻抗脉冲波的关系,提出了一个用生物电 阻抗法无创监护颅内压的理论。初步的动物实验表明该理论是可行的。

  6. Treatment of colour industry wastewaters with concomitant bioelectricity production in a sequential stacked mono-chamber microbial fuel cells-aerobic system.

    Science.gov (United States)

    Fernando, Eustace; Keshavarz, Taj; Kyazze, Godfrey; Fonseka, Keerthi

    2016-01-01

    The scalability of any microbial fuel cell (MFC)-based system is of vital importance if it is to be utilized for potential field applications. In this study, an integrated MFC-aerobic bioreactor system was investigated for its scalability with the purpose of treating a simulated dye wastewater and industrial wastewaters originated from textile dyebaths and leather tanning. The influent containing real wastewater was fed into the reactor in continuous mode at ambient temperature. Three MFC units were integrated to act in unison as a single module for wastewater treatment and a continuously stirred aerobic bioreactor operating downstream to the MFC module was installed in order to ensure more complete degradation of colouring agents found in the wastewater. Total colour removal in the final effluent exceeded 90% in all experiments where both synthetic (AO-7 containing) and real wastewater were used as the influent feed. The chemical oxygen demand reduction also exceeded 80% in all experiments under the same conditions. The MFC modules connected in parallel configuration allowed obtaining higher current densities than that can be obtained from a single MFC unit. The maximum current density of the MFC stack reached 1150 mA m(-2) when connected in a parallel configuration. The outcome of this work implies that suitably up-scaled MFC-aerobic integrated bioprocesses could be used for colour industry wastewater treatment under industrially relevant conditions with possible prospects of bioelectricity generation.

  7. 多频多段人体生物电阻抗测量系统%A Bioelectrical Impedance Measurement System Based on Multi-Frequency and Multi-Segment Technology

    Institute of Scientific and Technical Information of China (English)

    高秀娥; 唐佳; 陈波

    2012-01-01

    Bioelectrical impedance is an important composition of human body, and reflects the physical conditions of human tissues to some extent. Based on this, a multi-frequency and multi-segment bioelectrical impedance measurement system is designed on the principle of eight electrodes. In fact, the system, which consists of MCU system, sinusoidal excitation current source, RMS-to-DC circuit and etc, has achieved the impedance measurement of the extremities as well as the trunk under the frequency ranged from 5 ~ 500 kHz. Experiment results show that the system finally realizes high-accuracy measurements of amplitude and phase of bioelectrical impedance with the result of a relative error of magnitude which is less than 0. 7% and an absolute error of phase which is less than 0.8°.%人体生物电阻抗是人体体成分的重要组成部分,在一定程度上反映了人体组织的生理状况.基于此,设计了一套基于八电极的多频多段人体生物电阻抗测量系统.测量系统由单片机系统、正弦交流激励电流源、有效值检测电路等组成,实现了5 ~ 500 kHz频率范围的左右上下肢及躯干的5段测量.测试结果表明,测量系统实现了人体生物电阻抗的幅值和相位的高精度测量,幅值相对误差小于0.7%,相位绝对误差小于0.8°.

  8. Influence of agricultural residues interpretation and allocation procedures on the environmental performance of bioelectricity production – A case study on woodchips from apple orchards

    International Nuclear Information System (INIS)

    Highlights: • An LCA of bioelectricity production from apple woody residues (AWRs) is performed. • Two AWRs interpretation are investigated: by-products and co-products. • Different allocation procedures are used for upstream and downstream emissions. • AWRs guarantee significant environmental benefits, when interpreted as by-products. - Abstract: Agricultural woody residues are available in massive quantities and provide a considerable potential for energy production. However, to encourage environmentally sustainable bioenergy strategies, it is necessary to assess the environmental performance of each specific bioenergy chain. Life cycle assessment (LCA) is recognized to be one of the best methodologies to evaluate the environmental burdens of bioenergy chains. The application of LCA to bioenergy from agricultural residues requires practitioners to make choices on how to interpret agricultural residues (i.e. by-products or co-products) and on how to allocate emissions among the different products generated along the bioenergy chain. These are among the most debated issues in the LCA community, given their potentially large influence on final LCA outcomes. A uniform consensus on these issues is still lacking, and no single method is equally suitable for all solutions. The aim of this paper is to assess how different ways of agricultural residue interpretation and different allocation methods (both of upstream and downstream emissions), affect the environmental performance of bioenergy production fed by agricultural residues. In order to address the issue, we perform a full attributional LCA of the electricity production in a combustion combined heat and power plant (CHP) fed with woody residues from apple orchards (AWRs), as a case study. Bioelectricity production from CHP fed with agricultural residues is a good example of a multifunctional process, since multiple products (e.g. grain, fruit, straw, wood, etc.) and energy (e.g. heat and power) are co

  9. The variations of body mass index and body fat in adult Thai people across the age spectrum measured by bioelectrical impedance analysis

    Directory of Open Access Journals (Sweden)

    Chittawatanarat K

    2011-11-01

    Full Text Available Kaweesak Chittawatanarat1,2, Sakda Pruenglampoo3, Siriphan Kongsawasdi4, Busaba Chuatrakoon4, Vibul Trakulhoon5, Winai Ungpinitpong6, Jayanton Patumanond21Department of Surgery, Faculty of Medicine, 2Clinical Epidemiology Unit, 3Research Institute for Health Sciences, 4Department of Physical Therapy, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, 5Department of Surgery, Bhumibol Adulyadej Hospital, Bangkok, 6Surgical Unit, Surin Hospital, Surin, ThailandBackground: The measurements of body mass index (BMI and percentage of body fat are used in many clinical situations. However, special tools are required to measure body fat. Many formulas are proposed for estimation but these use constant coefficients of age. Age spectrum might affect the predicted value of the body composition due to body component alterations, and the coefficient of age for body fat prediction might produce inconsistent results. The objective of this study was to identify variations of BMI and body fat across the age spectrum as well as compare results between BMI predicted body fat and bioelectrical impedance results on age.Methods: Healthy volunteers were recruited for this study. Body fat was measured by bioelectrical impedance. The age spectrum was divided into three groups (younger: 18–39.9; middle: 40–59.9; and older: ≥60 years. Comparison of body composition covariates including fat mass (FM, fat free mass (FFM, percentage FM (PFM, percentage FFM (PFFM, FM index (FMI and FFM index (FFMI in each weight status and age spectrum were analyzed. Multivariable linear regression coefficients were calculated. Coefficient alterations among age groups were tested to confirm the effect of the age spectrum on body composition covariates. Measured PFM and calculated PFM from previous formulas were compared in each quarter of the age spectrum.Results: A total of 2324 volunteers were included in this study. The overall body composition and weight

  10. Indicaxanthin from Opuntia ficus-indica Crosses the Blood-Brain Barrier and Modulates Neuronal Bioelectric Activity in Rat Hippocampus at Dietary-Consistent Amounts.

    Science.gov (United States)

    Allegra, Mario; Carletti, Fabio; Gambino, Giuditta; Tutone, Marco; Attanzio, Alessandro; Tesoriere, Luisa; Ferraro, Giuseppe; Sardo, Pierangelo; Almerico, Anna Maria; Livrea, Maria Antonia

    2015-08-26

    Indicaxanthin is a bioactive and bioavailable betalain pigment from the Opuntia ficus-indica fruits. In this in vivo study, kinetic measurements showed that indicaxanthin is revealed in the rat brain within 1 h from oral administration of 2 μmol/kg, an amount compatible with a dietary consumption of cactus pear fruits in humans. A peak (20 ± 2.4 ng of indicaxanthin per whole brain) was measured after 2.5 h; thereafter the molecule disappeared with first order kinetics within 4 h. The potential of indicaxanthin to affect neural activities was in vivo investigated by a microiontophoretic approach. Indicaxanthin, administered in a range between 0.085 ng and 0.34 ng per neuron, dose-dependently modulated the rate of discharge of spontaneously active neurons of the hippocampus, with reduction of the discharge and related changes of latency and duration of the effect. Indicaxanthin (0.34 ng/neuron) showed inhibitory effects on glutamate-induced excitation, indicating activity at the level of glutamatergic synapses. A molecular target of indicaxanthin is suggested by in silico molecular modeling of indicaxanthin with N-methyl-D-aspartate receptor (NMDAR), the most represented of the glutamate receptor family in hippocampus. Therefore, at nutritionally compatible amounts indicaxanthin (i) crosses the rat BBB and accumulates in brain; (ii) can affect the bioelectric activity of hippocampal neurons locally treated with amounts comparable with those measured in the brain; and (iii) modulates glutamate-induced neuronal excitation. The potential of dietary indicaxanthin as a natural neuromodulatory agent deserves further mechanistic and neurophysiologic investigation. PMID:26227670

  11. Total body water and fat-free mass: evaluation of equations based on bioelectrical impedance analysis in infants and young children in India.

    Science.gov (United States)

    Sen, Bandana; Mahalanabis, Dilip; Kurpad, Anura V; Shaikh, Saijuddin; Bose, Kaushik

    2010-07-01

    The association of early postnatal growth with diseases in adults such as hypertension, type 2 diabetes and CHD has generated interest in studying postnatal growth. Bioelectrical impedance analysis (BIA) is a useful measure to estimate total body water (TBW) and fat-free mass (FFM). We evaluated three published equations (Fjeld et al. (Pediatr Res (1990) 27, 98-102), Bocage (MSc Thesis (1988) University of West Indies) and Kushner et al. (Am J Clin Nutr (1992) 56, 835-839) to measure TBW and derived FFM based on BIA, using 2H2O dilution as a reference method for suitability in infants in India. In a cross-sectional study in seventy-eight apparently healthy infants aged 6-24 months from the urban poor attending an immunisation clinic at a hospital in Kolkata, we measured their length to the nearest 0.1 cm, weight to the nearest 10 g, resistance at 50 kHz using BIA and TBW using 2H2O dilution. TBW was derived using three published BIA-based equations and compared with TBW using 2H2O dilution. Based on the BIA equations of Fjeld et al., Bocage and Kushner et al., the mean TBW values were 2.46 % (P < 0.001), 4.62 % (P < 0.001) and 9.50 % (P < 0.001) lower than the reference 2H2O method, respectively. All three published BIA-based equations consistently underestimated the TBW and FFM and appeared inadequate for studying infants in India. The equation described by Fjeld et al. gave the smallest deviation from the reference method and may be used for field studies. New equations based on population-specific data are desirable for a more precise measure of TBW. PMID:20188001

  12. A Comparison Study of Portable Foot-to-Foot Bioelectrical Impedance Scale to Measure Body Fat Percentage in Asian Adults and Children

    Directory of Open Access Journals (Sweden)

    Pei Ying Sim

    2014-01-01

    Full Text Available Objective. To compare the measurements of body fat percentage (BF% using the foot-to-foot bioelectrical impedance analysis (FTF-BIA with the direct segmental multifrequency BIA (DSM-BIA. Methods. There were 36 men and 52 women (37.1±14.3 years with 57% Malays, 30% Chinese, and 13% Indian. For children, there were 45 boys and 26 girls (11.5±2.5 years with 52% Malay, 15% Chinese, and 33% Indian. Results. Mean height for men was 168.4 cm, 11 cm taller than women. Men were 10 kg heavier than women at 70 kg. BF% in women was 32% and 33% whereas BF% in men was 23% and 25% when measured using FTF-BIA and DSM-BIA, respectively. In children, BF% measured with FTF-BIA and DSM-BIA was 49% and 46%, respectively. The correlations were significant for men (r=0.92, SEE = 2.80, women (r=0.91, SEE = 3.31, boys (r=0.95, SEE = 5.44, and girls (r=0.96, SEE = 5.27. The BF% in underweight/normal (r=0.92, SEE = 2.47 and that in overweight/obese adults (r=0.89, SEE = 3.61 were strongly correlated. The correlations were significant in normal/underweight (r=0.94, SEE = 3.78 and obese/overweight children (r=0.83, SEE = 6.49. All ethnic groups showed significant correlation with BF%. Malay adults (r=0.92, SEE = 3.27 and children (r=0.94, SEE = 0.88 showed significant mean differences in BF%. Conclusion. The FTF-BIA showed higher accuracy for all normal/underweight and Chinese group with acceptable overestimation in children and underestimation in adults. Caution should be taken when interpreting BF% depending on gender, BMI, and ethnicity.

  13. Evaluation of the BOD POD and leg-to-leg bioelectrical impedance analysis for estimating percent body fat in National Collegiate Athletic Association Division III collegiate wrestlers.

    Science.gov (United States)

    Dixon, Curt B; Deitrick, Ronald W; Pierce, Joseph R; Cutrufello, Paul T; Drapeau, Linda L

    2005-02-01

    The purpose of this study was to compare percent body fat (%BF) estimated by air displacement plethysmography (ADP) and leg-to-leg bioelectrical impedance analysis (LBIA) with hydrostatic weighing (HW) in a group (n = 25) of NCAA Division III collegiate wrestlers. Body composition was assessed during the preseason wrestling weight certification program (WCP) using the NCAA approved methods (HW, 3-site skinfold [SF], and ADP) and LBIA, which is currently an unaccepted method of assessment. A urine specific gravity less than 1.020, measured by refractometry, was required before all testing. Each subject had all of the assessments performed on the same day. LBIA measurements (Athletic mode) were determined using a Tanita body fat analyzer (model TBF-300A). Hydrostatic weighing, corrected for residual lung volume, was used as the criterion measurement. The %BF data (mean +/- SD) were LBIA (12.3 +/- 4.6), ADP (13.8 +/- 6.3), SF (14.2 +/- 5.3), and HW (14.5 +/- 6.0). %BF estimated by LBIA was significantly (p < 0.01) smaller than HW and SF. There were no significant differences in body density or %BF estimated by ADP, SF, and HW. All methods showed significant correlations (r = 0.80-0.96; p < 0.01) with HW. The standard errors of estimate (SEE) for %BF were 1.68, 1.87, and 3.60%; pure errors (PE) were 1.88, 1.94, and 4.16% (ADP, SF, and LBIA, respectively). Bland-Atman plots for %BF demonstrated no systematic bias for ADP, SF, and LBIA when compared with HW. These preliminary findings support the use of ADP and SF for estimating %BF during the NCAA WCP in Division III wrestlers. LBIA, which consistently underestimated %BF, is not supported by these data as a valid assessment method for this athletic group.

  14. Prediction of fat-free mass and percentage of body fat in neonates using bioelectrical impedance analysis and anthropometric measures: validation against the PEA POD.

    Science.gov (United States)

    Lingwood, Barbara E; Storm van Leeuwen, Anne-Martine; Carberry, Angela E; Fitzgerald, Erin C; Callaway, Leonie K; Colditz, Paul B; Ward, Leigh C

    2012-05-01

    Accurate assessment of neonatal body composition is essential to studies investigating neonatal nutrition or developmental origins of obesity. Bioelectrical impedance analysis or bioimpedance analysis is inexpensive, non-invasive and portable, and is widely used in adults for the assessment of body composition. There are currently no prediction algorithms using bioimpedance analysis in neonates that have been directly validated against measurements of fat-free mass (FFM). The aim of the study was to evaluate the use of bioimpedance analysis for the estimation of FFM and percentage of body fat over the first 4 months of life in healthy infants born at term, and to compare these with estimations based on anthropometric measurements (weight and length) and with skinfolds. The present study was an observational study in seventy-seven infants. Body fat content of infants was assessed at birth, 6 weeks, 3 and 4·5 months of age by air displacement plethysmography, using the PEA POD body composition system. Bioimpedance analysis was performed at the same time and the data were used to develop and test prediction equations for FFM. The combination of weight+sex+length predicted FFM, with a bias of < 100 g and limits of agreement of 6-13 %. Before 3 months of age, bioimpedance analysis did not improve the prediction of FFM or body fat. At 3 and 4·5 months, the inclusion of impedance in prediction algorithms resulted in small improvements in prediction of FFM, reducing the bias to < 50 g and limits of agreement to < 9 %. Skinfold measurements performed poorly at all ages.

  15. Indicaxanthin from Opuntia ficus-indica Crosses the Blood-Brain Barrier and Modulates Neuronal Bioelectric Activity in Rat Hippocampus at Dietary-Consistent Amounts.

    Science.gov (United States)

    Allegra, Mario; Carletti, Fabio; Gambino, Giuditta; Tutone, Marco; Attanzio, Alessandro; Tesoriere, Luisa; Ferraro, Giuseppe; Sardo, Pierangelo; Almerico, Anna Maria; Livrea, Maria Antonia

    2015-08-26

    Indicaxanthin is a bioactive and bioavailable betalain pigment from the Opuntia ficus-indica fruits. In this in vivo study, kinetic measurements showed that indicaxanthin is revealed in the rat brain within 1 h from oral administration of 2 μmol/kg, an amount compatible with a dietary consumption of cactus pear fruits in humans. A peak (20 ± 2.4 ng of indicaxanthin per whole brain) was measured after 2.5 h; thereafter the molecule disappeared with first order kinetics within 4 h. The potential of indicaxanthin to affect neural activities was in vivo investigated by a microiontophoretic approach. Indicaxanthin, administered in a range between 0.085 ng and 0.34 ng per neuron, dose-dependently modulated the rate of discharge of spontaneously active neurons of the hippocampus, with reduction of the discharge and related changes of latency and duration of the effect. Indicaxanthin (0.34 ng/neuron) showed inhibitory effects on glutamate-induced excitation, indicating activity at the level of glutamatergic synapses. A molecular target of indicaxanthin is suggested by in silico molecular modeling of indicaxanthin with N-methyl-D-aspartate receptor (NMDAR), the most represented of the glutamate receptor family in hippocampus. Therefore, at nutritionally compatible amounts indicaxanthin (i) crosses the rat BBB and accumulates in brain; (ii) can affect the bioelectric activity of hippocampal neurons locally treated with amounts comparable with those measured in the brain; and (iii) modulates glutamate-induced neuronal excitation. The potential of dietary indicaxanthin as a natural neuromodulatory agent deserves further mechanistic and neurophysiologic investigation.

  16. Effect of the ethinylestradiol/norelgestromin contraceptive patch on body composition. Results of bioelectrical impedance analysis in a population of Italian women

    Directory of Open Access Journals (Sweden)

    Bruni Vincenzina

    2008-08-01

    Full Text Available Abstract Background As weight gain is one of the most frequently cited reasons for not using and for discontinuing hormonal contraceptives, in an open-label, single-arm, multicentre clinical study we evaluated the effect of the ethinylestradiol/norelgestromin contraceptive patch (EVRA, Janssen-Cilag International, Belgium on body composition using bioelectrical impedance analysis (BIA. Methods Body weight and impedance vector components (resistance (R and reactance (Xc, at 50 kHz frequency, Akern-RJL Systems analyzer were recorded before entry, after 1, 3 and 6 months in 182 Italian healthy women aged 29 yr (18 to 45, and with BMI 21.8 kg/m2 (16 to 31. Total body water (TBW was estimated with a BIA regression equation. Vector BIA was performed with the RXc mean graph method and the Hotelling's T2 test for paired and unpaired data. Results After 6 months body weight increased by 0.64 kg (1.1% and TBW increased by 0.51 L (1.7%. The pattern of impedance vector displacement indicated a small increase in soft tissue hydration (interstitial gel fluid. Body composition changes did not significantly differ among groups of previous contraceptive methods. Arterial blood pressure did not significantly change over time. Conclusion After 6 months of treatment with the ethinylestradiol/norelgestromin contraceptive patch we found a minimal, clinically not relevant, increase in body weight less than 1 kg that could be attributed to an adaptive interstitial gel hydration. This fluctuation is physiological as confirmed by the lack of any effect on blood pressure. This could be useful in increasing women's choice, acceptability and compliance of the ethinylestradiol/norelgestromin contraceptive patch.

  17. Induced bioelectrical signal in human nervous system and its significance to the research of neuron-threshold%人体神经系统应激生物电信号对神经阈值研究的作用

    Institute of Scientific and Technical Information of China (English)

    汤黎明; 常本康; 刘铁兵; 吴敏

    2003-01-01

    AIM: To design a type of circuit for measuring the parameter of induced bioelectrical signal,and apply it in the research of induced bioelectrical signal's character. METHODS:This circuit was designed according to the character of induced bioelectrical signals.It was tested and improved and then used in the neuron-threshold stimulator. RESULTS:The circuit was found to be very accurate for measuring frequency and the error for measuring duty cycle was below 0.2% . CONCLUSION: This circuit is accurate, real-time in measuring, simple in designing, and can be applied in many systems.%目的 :设计一种人体应激生物电信号参数测量电路,以研究人体应激生物电信号的特性. 方法 :根据人体神经系统应激生物电信号的频率较低并且极其不规则,以及频率和占空比变化非常频繁等特性,构思电路原理,然后进入实际设计、测试和改进,最终将其应用于精密神经阈值刺激仪中. 结果 :电路经调试和改进,应用 Agilent 33120A数字函数信号发生器和 TDS3034B数字存贮示波器对多种波型、多种频率和占空比的信号进行测量,测量电路对各种信号频率的测量是相当准确的,对占空比的测量误差 < 0.2%,基于该电路的精密神经阈值刺激仪经临床试用,取得满意的效果. 结论 :实践证明,该电路具有测量结果准确、实时,电路结构简单等优点.

  18. 生物电阻抗铜片电极的化学刻蚀工艺%Chemical etching process of copper electrode for bioelectrical impedance technology

    Institute of Scientific and Technical Information of China (English)

    周伟; 宋嵘; 蒋乐伦; 许文平; 梁国开; 程德才; 刘灵蛟

    2012-01-01

    为获得具有强稳定性能的生物电阻抗电极,采用化学刻蚀加工方法,制造出表面具有一系列微结构的金属铜片电极.通过改变加工工艺参数的方法,着重分析刻蚀时间、刻蚀温度、刻蚀液体浓度、样品尺寸等刻蚀工艺参数对铜片电极的蚀刻速率和表面微结构的影响.结果表明:刻蚀速率将随着刻蚀时间的延长而逐渐降低,随着刻蚀温度的升高而逐渐升高,而刻蚀样本尺寸对刻蚀速率的影响不大.选用合适的刻蚀液体浓度(组分3),在室温条件下刻蚀20 min,可以获得具有丰富表面微结构的铜片电极.另外,进行24 h电极对接的连续性交流阻抗测试,与心电电极相比,利用化学刻蚀加工的铜片电极,由于表面具有丰富的表面微结构,可以形成可靠的表面接触,从而具有稳定的交流阻抗值.%In order to obtain bioelectrical impedance electrodes with high stability,the chemical etching process was used to fabricate the copper electrode with a series of surface microstructures.By changing the etching processing parameters,some comparison experiments were performed to reveal the influence of etching time,etching temperature,etching liquid concentration,and sample sizes on the etching rate and surface microstructures of copper electrode.The result shows that the etching rate is decreased with increasing etching time,and is increased with increasing etching temperature.Moreover,it is found that the sample size has little influence on the etching rate.After choosing the reasonable etching liquid composition (formulation 3),the copper electrode with many surface microstructures can be obtained by chemical etching process at room temperature for 20 min.In addition,using the alternating current impedance test of electrode-electrode for 24 h,the copper electrode with a series of surface microstructures fabricated by the etching process presents a more stable impedance value compared with the

  19. 一种基于FPGA的数字EIT系统的实验研究%A Bioelectricity Impedance Measurement System Research Based on FPGA

    Institute of Scientific and Technical Information of China (English)

    孙晓彤; 郝会玲; 沙洪

    2013-01-01

    以FPGA芯片为核心的数字化生物电阻抗测量实验平台,主要完成直接数字频率合成(DDS)的电流源模块、V/I变换和数字解调模块的研究.采用DDS技术生成正弦信号发生器,由THS4021改进的Howland电路设计压控电流源,在不同负载条件下测量其输出电流幅值的频率响应,并在不同频率下测量电流源的输出阻抗,对恒流源性能的稳定性和精度进行测定.解调方法采用数字化解调,测试不同激励频率下的数字正交解调输出误差变化情况.最后采用盐水槽实验系统进行成像实验.结果表明,电流源可在6.1~390.6 kHz范围输出多频激励信号,在600 kHz前保持在190 kΩ的输出阻抗.当信号频率从200 kHz逐渐增加到1.6 MHz时,解调电路输出的I和Q路误差逐渐增加,对应的幅度误差从1.13%增加到7.19%,相位误差从1.03%增大到5.34%.采用相邻激励-相邻测量模式对环氧树脂棒进行盐水槽成像实验,成像结果表明系统能够对单个目标物体实现较准确的定位,验证了本研究平台的可行性.%In this work the digital bioelectricity impedance measurement experiment platform with the core of FPGA was studied and completed the research of the DDS module,V/I conversion and digital demodulation.DDS technology was used to generate a sinusoidal signal generator.Howland circuit improved by THS4021 was used to design a voltage-controlled current source,the amplitude of the output current of the frequency response was measured in different load conditions,and the output impedance of the current source was measured at different frequencies,which proved stability and accuracy of the constant current source.The digital demodulation was used in the study and tested digital quadrature demodulation output error under different excitation frequency.At last we used salt water tank experimental system for imaging experiments.The current source could produce multi-frequency excitation signal in

  20. Study of cystatin C (Cys C in relation to the calculation of the glomerular filtration rate and bioelectrical impedance analysis parameters in obese patients with and without type 2 diabetes

    Directory of Open Access Journals (Sweden)

    Mario Liani

    2012-01-01

    Full Text Available IntroductionAssessment of renal function based on quantification of the glomerular filtration rate (GFR is essential for early detection of damage and progression of renal diseases. The purpose of our study was to determine the value of cystatin C (Cys C assays in the calculation of the GFR and bioelectrical impedance analysis parameters in obese subjects aged 30-70 years with moderately damaged renal function.Materials and methodsCys C levels were measured with a new immunoturbidimetric kit (Roche Diagnostics and an automated Cobas c6000 analyzer. In the GFR calculation, creatinine and Cys C levels were included. The GFR calculated with the equation that included Cys C in obese and normal-weight patients is not affected by changes in the lean body mass.ResultsObese patients (N = 70 had a mean (± SD serum creatinine level of 1.52 ± 1.0 mg/dL and a mean Cys C level of 1.28 ± 0.59 mg/L. In this group, the GFR calculated on the basis of MDRD, Cys C, and creatinine clearance values showed similar filtered values between MDRD and Cys C and a DS value smaller in the case of Cys C. The correlation (R2 between GFR and its metabolite is higher in the case of Cys C when somatotype parameters (measured with bioelectrical impedance analysis were introduced into the equation.ConclusionsWhen Cys C is included in calculations of GFR, the result shows a higher correlation degree compared to the MDRD system. Given that Cys C shows less intra-individual variability than creatinine, it can be applied in routine diagnostics in a larger number of patients.

  1. Bioelectric modulation of macrophage polarization

    OpenAIRE

    Chunmei Li; Michael Levin; Kaplan, David L.

    2016-01-01

    Macrophages play a critical role in regulating wound healing and tissue regeneration by changing their polarization state in response to local microenvironmental stimuli. The native roles of polarized macrophages encompass biomaterials and tissue remodeling needs, yet harnessing or directing the polarization response has been largely absent as a potential strategy to exploit in regenerative medicine to date. Recent data have revealed that specific alteration of cells’ resting potential (Vmem)...

  2. Application of cardiac output measurement by bioelectrical impedance in critically ill patients%生物电阻抗法监测心输出量在危重病中的应用

    Institute of Scientific and Technical Information of China (English)

    刘紫锰; 杨春华; 陈娟; 欧阳彬; 管向东

    2009-01-01

    目的 探讨生物电阻抗法测量无创心输出量(CO)在危重病中应用的准确性和有效性.方法 选择2008年1月至5月间本院外科重症监护中心(SICU)收治的12例需放置SWAN-GANZ导管进行血流动力学监测的患者,同时用生物电阻抗法和SWAN-GANZ导管热稀释法测定患者CO曲线平稳后0、1、6、12、24、48 h的CO值,并应用Pearson相关对两种方法测得的CO值与时间进行分析.结果 生物电阻抗法测最的CO值在所有时间点均低于SWAN-GANZ导管热稀释法的测最值[0 h:(5.5±0.9)L/min比(7.7±1.4)L/min;1h:(5.3±0.7)L/min比(7.4±1.5)L/min;6 h:(4.6±0.6)L/min比(6.8±1.4)L/min;12 h:(5.1±0.9)L/min比(7.6±1.6)L/min;24 h:(6.1±1.1)L/min比(9.0±1.6)L/min;48 h:(6.3±1.3)L/min比(9.5±1.5)L/min;均P<0.05].两种方法测量的CO值均随着时间的延长而呈升高趋势(r=0.818,P=0.047和r=0.884,P=0.020).结论 生物电阻抗法测量的无创CO与SWAN-GANZ导管测定的患者CO同样呈时间依赖性,是一种有效的CO监测方法.%Objective To evaluate the efficacy and accuracy of non-invasive bioelectrical impedance measurement of cardiac output (CO) in critically ill patients. Methods Between January and May 2008, 12 patients who needed hemodynamics monitoring using SWAN-GANZ catheterization in surgical intensive care unit (SICU) of our hospital were measured for CO by bioelectrical impedance and SWAN-GANZ catheterization thermodilution approaches. These values were recorded at 0, 1, 6, 12, 24 and 48 hours after the CO curve became stable in these patients. Pearson correlation analysis was performed for CO values over time recorded by these two approaches. Results At all the time points, CO measurement by bioelectrical impedance yielded lower values than those by SWAN-GANZ catheterization thermodilution approach [0 h: (5.5±0.9) L/min vs (7.7±1.4) L/min; 1 h: (5.3±0.7) L/min vs (7.4±1.5) L/min; 6 h: (4.6±0.6) L/min vs (6.8±1.4) L/min; 12 h: (5.1±0.9) L/min vs (7.6±1.6) L

  3. 应用生物电阻抗法测定体育专业学生身体成分%Determination of compsitionof students' body of physical education specialty with bioelectrical impedance analysis

    Institute of Scientific and Technical Information of China (English)

    郭玉萍

    2011-01-01

    By using bioelectrical impedance analysis,major students' body composition of physical education are tested and analysed in this research.The results show that the fatfree mass of the students is insufficient,while the body fat mass is surplus and the body compsition of the students is unreasonable.A suggestion is made that the students should increase the muscular strength practice,and at the same time balance their nutrition of meals.The students' physical fitness can be improved.%应用生物电阻抗法,对体育专业学生进行了身体成分的测评与分析。结果显示,学生瘦体重不足,体脂肪率偏高,体成分不合理。建议制定科学合理的运动训练方案,增强肌肉力量性练习,配合膳食营养,改善学生体质状况。

  4. The Comparison of Multi-frequency Bioelectrical Impedance Analysis and the MoistureMeterD Compact on Detecting Tissue Edema in Secondary Lymphedema of Upper Limb%多频生物电阻抗分析仪与接触式水份测量仪对继发性上肢淋巴水肿检测的准确性比较

    Institute of Scientific and Technical Information of China (English)

    罗毅; 严志新; 汪立; 陈佳佳; 刘宁飞

    2014-01-01

    Objective To compare the accuracy of multi -frequency bioelectrical impedance analysis and the MoistureMeterD Compact to detect tissue edema in secondary lymphedema of upper limb. Methods Eighteen patients with secondary lymphedema after radical mastectomy, treated by manual lymph drainage, were randomly selected in this study. The measurement of circumference of upper limb was determined as standard, which had an correlation analysis with multi-frequency bioelectrical impedance analysis and MoistureMeterD Compact ’s results on tissue edema change. Results Accoring to the circumference change and the measured results of multi-frequency bioelectrical impedance analysis and the MoistureMeterD Compact, the degree of lymphedema was decreased after treatment. The multifrequency bioelectrical impedance’s test results had an relatively higher correlation (r=0.579, P<0.05) with the results of the standard, comparing to the results of the MoistureMeterD Compact (r=0.490, P<0.05). Conclusion Both multi-frequency bioelectrical impedance analysis and the MoistureMeterD Compact could be used for the measurement of lymphedema of upper limb, and multifrequency bioelectrical impedance analysis have an higher accuracy in the measurement of tissue edema.%目的:以周径测量结果为标准,比较多频生物电阻抗分析仪与接触式水分测量仪检测继发性上肢淋巴水肿的准确性。方法随机选取在我科进行淋巴手法引流治疗乳腺癌根治术后继发性上肢淋巴水肿患者18名,以周径测量获得的上肢增粗程度为标准,将多频生物电阻抗分析仪和接触式水分测量仪对组织水肿的检测结果,与周径改变进行相关性分析。结果患肢周径变化和两种水分测量的结果均显示患者治疗后水肿程度减轻。相比接触式水分测量仪的结果(r=0.490,P<0.05),多频生物电阻抗分析仪的测试结果(r=0.579,P<0.05)与周径测量结果相关性系数更高

  5. 生物电阻抗法在慢性肾脏病儿童营养评估中的应用%Application of bioelectrical impedance analysis in the assessment of nutritional status in children with chronic kidney disease

    Institute of Scientific and Technical Information of China (English)

    吴冬雪; 孟群; 沈颖

    2014-01-01

    目的:探讨生物电阻抗原理(bioelectrical impedance analysis, BIA)在评价慢性肾脏病儿童营养方面的临床应用价值。方法选取2009年至2011年期间就诊于北京儿童医院肾脏内科的单中心慢性肾脏病(chronic kid-ney disease, CKD)患儿57例(CKD组),同时选择健康儿童54例作为正常对照组。利用生物电阻抗原理对儿童进行人体成分(主要包括蛋白质、脂肪含量的测定)的评估及比较。结果 CKD组蛋白质相对含量为(14.72±2.44)%,正常对照组为(18.10±3.91)%,两组间差异有统计学意义(t=2.61,P=0.000);CKD组脂肪相对含量为(24.31±12.52)%,显著高于正常对照组的(16.1±17.34)%,差异有统计学意义(t=3.89,P=0.000);CKD1~2期患儿蛋白质相对含量为(34.57±7.39)%,CKD3~5期患儿含量为(41.08±5.53)%,两者比较差异有统计学意义(t=3.749,P=0.000);CKD1~2期患儿相对脂肪含量为(28.73±12.50)%,CKD3~5期患儿含量为(16.13±7.52)%,其差异有统计学意义(t=-4.745,P=0.000)。 CKD组中47例(82.45%)处于营养成分失衡状态;在身高别体重提示营养状况良好的32例CKD患儿中25例(78.12%)存在营养成分不均衡。结论 CKD患儿存在蛋白质、脂肪等人体成分不均衡状态,个体化、针对性的营养管理对CKD患儿的营养状况改善有一定帮助。生物电阻抗原理对于评价CKD患儿营养状况有一定的临床应用价值。%Objectives To evaluate the nutritional status of children with chronic kidney disease(CKD) by bioelec-trical impedance analysis (BIA) and explore the value of BIA in assessing the nutritional status of children with CKD. Methods Fifty-seven patients with CKD who were hospitalized in Beijing Children's Hospital from 2009 to the end of 2011 were enrolled in this study. They were classified to be stages 1-5 according to the recommendation by the National Kidney

  6. 应用生物电阻抗法评估维持性血液透析患者营养状况%Application of Bioelectrical Impedance Analysis in Patients under Maintenance Hemodialysis

    Institute of Scientific and Technical Information of China (English)

    洪海兰; 王莲凤; 杨彩娟; 黄冬玲

    2012-01-01

    目的:应用生物电阻抗法(BIA)评估维持性血液透析(MHD)患者的营养状况,为临床采取有效的营养干预提供科学依据.方法:测量56例MHD患者与60名健康志愿者的体重(WT)、体质指数(BMI)、体脂肪量(FM)、瘦体重(LBM)(即非脂肪量FFM)和体脂肪率(Fat%),用描述性研究的方法分析不同的性别、年龄及BMI的MHD患者的人体成分.结果:MHD患者人体成分的各项参数值均显著低于健康志愿者.在体质指数无显著差异的前提下,男性MHD患者的FM和Fat%低于女性,≥45岁的MHD患者FM和Fat%明显高于<45岁的患者.比较不同BMI的MHD患者的人体成分也存在显著差异.结论:应用BIA测定MHD患者的人体成分准确、无创、快捷,对有效评估MHD患者的营养状况有着重要意义.%Objective: Bioelectrical impedance analysis( BIA) was applied to assess nutritional status of maintenance hemodialysis patients( MHD) ,to provide a scientific basis for clinical effective nutrition intervention. Methods:56 cases of MHD patients and 60 healthy volunteers were involved,weight(WT) ,body mass index(BMI) ,fat mass(FM) ,lean body mass(LBM) (that is,fat -free mass,FFM)and body fat percentage were measured. Descriptive research method was used to analyze different gender, age and BMI in MHD patients of different body composition. Results:MHD patients of the body composition were significantly lower than healthy volunteers. Based tin ao significant difference in body mass index, FM and Fat % of male MHD patients were less than that of women, FM and Fat% of patients more than 45 years old were higher than that of the patients less than 45. Comparing the body composition among MHD patients with different BMI, there are significant differences. Conclusion-. Application of BIA in MHD patients was accurate,non - invasive and quick and it has important significance for assessment of the nutritional status of MHD patients.

  7. A histochemical study of promoting peripheral nerve regeneration with simulated bioelectrical impulse of phrenic nerve%模拟膈神经生物电刺激促进周围神经再生的实验研究

    Institute of Scientific and Technical Information of China (English)

    夏奕俊; 徐向阳; 崔茂龙; 王成

    2004-01-01

    目的研究膈神经生物电脉冲(bioelectrical impulse of phrenic nerve,BIPN)在周围神经再生过程中的作用.方法取家兔18只,共36根坐骨神经,平均分为3组.A组为模拟膈神经生物电脉冲(BIPN)组.B组为连续方波脉冲刺激组.C组为不作任何刺激对照组.术后4周,取材检测.神经标本比较神经纤维计数、截面积及远端有髓纤维通过率.取胫前肌标本检测肌纤维截面积.结果 A、B、C 3组的神经缝合口远端有髓神经纤维计数分别为1236.9+202、1082.5+214.6和840.6+174.4根.A、B 2组比较,差异有统计学意义(t值3.323、P值<0.01).A、B、C 3组的神经纤维通过率分别为58.5+7.01、53.2+10.4和35.2+7.3%.A、B 2组比较,差异有统计学意义(t值2.221、P值<0.05).A、B、C 3组的神经纤维截面积分别为127.4+7.2、119.1+5.2和118.8+5.5μm2. A、B 2组比较,差异有统计学意义(t值4.398、P值<0.01).A、B、C 3组的肌纤维截面积分别为704.8+108.5、623.3+189.1和580.5+108.3 μm2 .A、B 2组比较,差异有统计学意义(t值2.308、P值<0.05).结论模拟膈神经电脉冲能有效促进周围神经损伤后的神经纤维再生.

  8. Are ethnic and gender specific equations needed to derive fat free mass from bioelectrical impedance in children of South asian, black african-Caribbean and white European origin? Results of the assessment of body composition in children study.

    Directory of Open Access Journals (Sweden)

    Claire M Nightingale

    Full Text Available BACKGROUND: Bioelectrical impedance analysis (BIA is a potentially valuable method for assessing lean mass and body fat levels in children from different ethnic groups. We examined the need for ethnic- and gender-specific equations for estimating fat free mass (FFM from BIA in children from different ethnic groups and examined their effects on the assessment of ethnic differences in body fat. METHODS: Cross-sectional study of children aged 8-10 years in London Primary schools including 325 South Asians, 250 black African-Caribbeans and 289 white Europeans with measurements of height, weight and arm-leg impedance (Z; Bodystat 1500. Total body water was estimated from deuterium dilution and converted to FFM. Multilevel models were used to derive three types of equation {A: FFM = linear combination(height+weight+Z; B: FFM = linear combination(height(2/Z; C: FFM = linear combination(height(2/Z+weight}. RESULTS: Ethnicity and gender were important predictors of FFM and improved model fit in all equations. The models of best fit were ethnicity and gender specific versions of equation A, followed by equation C; these provided accurate assessments of ethnic differences in FFM and FM. In contrast, the use of generic equations led to underestimation of both the negative South Asian-white European FFM difference and the positive black African-Caribbean-white European FFM difference (by 0.53 kg and by 0.73 kg respectively for equation A. The use of generic equations underestimated the positive South Asian-white European difference in fat mass (FM and overestimated the positive black African-Caribbean-white European difference in FM (by 4.7% and 10.1% respectively for equation A. Consistent results were observed when the equations were applied to a large external data set. CONCLUSIONS: Ethnic- and gender-specific equations for predicting FFM from BIA provide better estimates of ethnic differences in FFM and FM in children, while generic equations

  9. Impact of filtration elements on bioelectrical signal

    Science.gov (United States)

    Grigoriev, M.; Babich, L.

    2016-04-01

    Filtering of the wanted signal from the noise caused by power lines, magnetic pickup, interference from body movement, etc. in the field of medical data processing is a weighty problem of cardiography. To date, different types of digital filters have been used to clear the signal from unnecessary frequency bands. This paper presents the results of the filter simulation in MATLAB package.

  10. Bioelectrical impedance analysis of bovine milk fat

    International Nuclear Information System (INIS)

    Three samples of 250ml at home temperature of 20°C were obtained from whole, low fat and fat free bovine UHT milk. They were analysed by measuring both impedance spectra and dc conductivity in order to establish the relationship between samples related to fat content. An impedance measuring system was developed, which is based on digital oscilloscope, a current source and a FPGA. Data was measured by the oscilloscope in the frequency 1 kHz to 100 kHz. It was showed that there is approximately 7.9% difference in the conductivity between whole and low fat milk whereas 15.9% between low fat and free fat one. The change of fatness in the milk can be significantly sensed by both impedance spectra measurements and dc conductivity. This result might be useful for detecting fat content of milk in a very simple way and also may help the development of sensors for measuring milk quality, as for example the detection of mastitis.

  11. Determination of Composition of Students'body of Physical Dducation Specialty with Bioelectrical Impedance Analysis in Heze University%运用生物电阻抗法测定菏泽学院体育专业学生身体成分的研究

    Institute of Scientific and Technical Information of China (English)

    李建萍

    2015-01-01

    By using bioelectrical impedance analysis,major students' body composition of physical education in Heze College include fat,brawn, body moisture (fluid in the cell, extracellular fluid), protein and so on carries on the research analysis and development situation of sports professional students have a detailed understanding, and for the sports college students to provide a scientific basis for rational diet. Through body composition of 270 students in physical education found that students' slightly lighter weight, higher body fat rate, body composition is not reasonable.%应用生物电阻抗法(BIA)通过对菏泽学院体育专业学生的基本身体成分院脂肪量、筋肉量、体水分(细胞內液、细胞外液)、蛋白质等进行研究分析,对体育专业的学生的营养、发育情况有了详细的了解,并为体育专业学生的合理膳食提供科学的依据。通过对体育专业的270名学生的身体成分进行研究发现,学生的体重稍轻,体脂肪率偏高,体成分不合理。

  12. INFLUÊNCIA DE DIFERENTES TIPOS DE ELETRODOS SOBRE OS VALORES DA BIOIMPEDÂNCIA CORPORAL E NA ESTIMATIVA DE MASSA MAGRA (MM EM GATOS ADULTOS INFLUENCE OF DIFFERENT TYPES OF ELECTRODES ON THE BIOELECTRICAL IMPEDANCE VALUES AND IN THE ESTIMATION OF LEAN BODY MASS (LBM IN ADULT CATS

    Directory of Open Access Journals (Sweden)

    Thassila Caccia Feragi Cintra

    2010-04-01

    Full Text Available A bioimpedância (BIC é um método que aplica à tecnologia da impedância no estudo da composição corporal pela avaliação da diferença da condutividade elétrica dos tecidos. Os resultados da BIC são expressos pelas medidas primárias de resistência (R e reatância (Xc. Neste experimento, o método foi desenvolvido para verificar a viabilidade do uso de três diferentes tipos de eletrodos sobre a reprodutibilidade dos valores de R e Xc em gatos adultos. As médias de R e Xc com adesivos e agulhas de acupuntura não diferiram entre si (p?0,05, e os menores valores dos coeficientes de variação obtidos com estes eletrodos sinalizaram para uma melhor reprodutibilidade dos resultados quando comparados com os da agulha hipodérmica. Os diferentes tipos de eletrodos não interferiram nos valores da massa magra (MM estimada por equação específica, porém a agulha de acupuntura mostrou ser o eletrodo mais estável e de melhor aplicabilidade. A MM determinada com os diferentes tipos de eletrodos foi superior (p?0,05 à obtida com a absorciometria de raios-x de dupla energia (DEXA, provavelmente decorrente da equação utilizada na sua estimativa.

    PALAVRAS-CHAVES: Composição corporal, felinos, impedância, massa magra.
    The bioelectrical impedance is a method that applies impedance technology in the study of physical composition by evaluation of electrical conductivity difference on each organism tissue. The results of bioelectrical impedance (BIC are expressed by the resistance (R and reactance (Xc primary measures. This study was carried out to verify the viability of the use of three different electrodes on the repeatability of R and Xc values in adult cats. The averages of R and Xc estimated by adhesive and acupuncture needles did not differ from each other (p?0.05 and the smaller values of the variation coefficient acquired with these electrodes signaled for a better reproducibility of the results when compared with

  13. Grado de acuerdo entre los índices adiposo-musculares obtenidos a partir de medidas antropométricas del brazo, pliegues cutáneos e impedancia bioeléctrica Interchangeability of the fat-to-fat-free mass ratios obtained by arm anthropometric measures, skinfold thickness and bioelectrical impedance

    Directory of Open Access Journals (Sweden)

    V. Martín Moreno

    2003-04-01

    agreement among the fat-to-fat-free mass ratios obtained by arm anthropometric measures (fat-muscle index, FMI, Siri equation for the sum of four skinfold thickness (body fat-muscle index, BFMI Siri and triceps skinfold (BFMItriceps and bioelectrical impedance (BFMI Omron methods. Methods: This is a cross-sectional study. A total of 145 patients were evaluated by anthropometry and bioelectrical impedance (Omron BF 300(, being estimated the agreement through the Intraclass Correlation Coefficient (ICC and Bland-Altman method. The reference method was BFMI Siri. Results: The ICC between BFMI Siri - BFMItriceps were 0,9304 (0,9035; 0,9498, between BFMI Siri - FMI of 0,7726 (0,6846; 0,8361 and between BFMI Siri - BFMI Omron of 0,9114 (0,8771; 0,9361. BFMItriceps (limits of agreement -0,171 to 0,117 show the best agreement according to Bland-Altman analysis with BFMI Siri, followed by BMFI Siri - BFMI Omron (-0,186; 0,178. The agreement limits between FMI and BFMI Siri (-0,2; 0,42, BFMItriceps (-0,26; 0,42 or BFMI Omron (-0,292; 0,504 were beyond of the established cut-off points (-0,2; 0,2. Conclusions: Due to the nature of the statistical agreement BFMItriceps and BFMI Omron are methods interchangeable methods between them and with BFMI Siri. FMI is not interchangeable with BFMI Siri, BFMI Omron or BFMItriceps. These results suggest that FMI cannot estimate properly the body composition. BFMItriceps and BFMI Omron are valid alternative methods to be used instead BFMI Siri in the fat-to-fat-free mass ratio assessment.

  14. 多频生物电阻抗技术评价 COPD 患者营养状况及其与血气分析指标的相关性%Evaluation of Nutritional Status in COPD Patients by Multi - frequency Bioelectrical Impedance and Its Correlation With Blood Gas Indicators

    Institute of Scientific and Technical Information of China (English)

    黄陈; 朱文艺; 徐静; 李利; 樊荣; 李琦; 王建

    2015-01-01

    Objective To examine the body composition of COPD patients by multi - frequency bioelectrical impedance and investigate the relationship between body composition and blood gas indicators in order to provide clinical references for nutritional support for COPD patients. Methods We enrolled 62 patients who was hospitalized and diagnosed with COPD in the Department of Respiratory Medicine of Xinqiao Hospital from January to June in 2011. Multi - frequency bioelectrical impedance was used to detect the patients' physical composition. We collected data of serum total protein,albumin, prealbumin,hemoglobin,lymph cell count,blood gas( PaCO2 ,PaO2 and SpO2 ),HCO -3 ,Cl - ,K + ,Na + ,pH of the subjects at admission. Statistical analysis was conducted on the above indicators. Results The malnutrition rates assessed by ribosomal protein content,body fat content,BMI and MAC were 41. 9% ,17. 7% ,19. 4% and 16. 1% , respectively. According the BMI,the patients with inadequate,normal and excess nutrition were significantly different( P < 0. 05 )in ribosomal TBW,BFM,PBF,FFM,PBFF,protein content and PBP;the subjects with inadequate nutrition were higher(P <0. 05)than those with normal and high nutrition in PBP;the subjects with inadequate nutrition were lower( P < 0. 05)than those with normal and high nutrition in PBF and FFM. TBW,FFM,ribosomal protein,and SMM were negatively correlated with PaO2 ( r = - 0. 311, - 0. 306, - 0. 308, - 0. 306;P < 0. 05),and BMI was negatively correlated with SpO2 ( r =- 0. 304,P < 0. 05). Conclusion COPD patients have high malnutrition rate when assessed by ribosomal protein. FFM is more sensitive than BMI in nutritional evaluation of COPD patients. The increase of FFM in COPD patients may improve hypoxia tolerance.%目的:应用多频生物电阻抗技术分析 COPD 患者人体成分及其与血气分析指标的关系,为 COPD 患者的营养支持提供依据。方法选择2011年1—6月在新桥医院呼吸科住院并诊断为 COPD

  15. A comparison of fat mass and skeletal muscle mass estimation in male ultra-endurance athletes using bioelectrical impedance analysis and different anthropometric methods Comparación de la masa grasa y muscular estimada en atletas varones de ultra-resistencia utilizando la bioimpedancia eléctrica y diferentes métodos antropométricos

    Directory of Open Access Journals (Sweden)

    B. Knechtle

    2011-12-01

    Full Text Available Two hundred and fifty seven male Caucasian ultraendurance athletes were recruited, pre-race, before different swimming, cycling, running and triathlon races. Fat mass and skeletal muscle mass were estimated using bioelectrical impedance analysis (BIA and anthropometric methods in order to investigate whether the use of BIA or anthropometry would be useful under field conditions. Total body fat estimated using BIA was significantly high (P Se reclutaron a 257 hombres caucasianos que eran atletas de alto rendimiento, antes de competir en diferentes pruebas triatlón de natación, ciclismo y carrera. Se estimaron la masa grasa y la masa de músculo esquelético utilizando un análisis de impedancia bioeléctrica (BIA y métodos antropométricos con el fin de investigar si el uso de BIA o de la antropometría sería útil en tales condiciones de campo. La grasa corporal total estimada por BIA fue significativamente mayor en comparación con la antropometría (P < 0,001. Cuando se compararon los resultados entre BIA y antropometría, se encontraron niveles de concordancia bajos a moderados. Estos resultados concuerdan con las diferencias halladas con el análisis Bland-Altman, lo que indica que la ecuación antropométrica de Ball et al. posee el mayor grado de concordancia (desviación = -3,0 ± 5,8 kg con BIA, con Stewart et al. (desviación = -6,4 ± 6,3 kg, Faulkner (desviación = -4,7 ± 5,8 kg y Wilmore-Siri (desviación = -4,8 ± 6,2 kg. La estimación de la masa de músculo esquelético fue significativamente superior con BIAS que con antropometría (P < 0,001. Los resultados de la ICC y del método Bland-Altman muestran que la ecuación antropométrica de Lee et al. (desviación = -5,4 ± 5,3 kg produjo el mayor grado de concordancia. El método combinado de Janssen et al. entre antropometría y BIA mostró el menor grado de concordancia (desviación = -12,5 ± 5,7 kg. Hubo una diferencia estadísticamente significativa entre los resultados

  16. Comparison of bioelectrical impedance with skinfold thickness and X-ray absorptiometry to measure body composition in HIV-infected with lipodistrophy Comparación de impendancia bioeléctrica con grosor de pliegues cutáneos y absorciometría de rayos X para mensurar la composición corporal de personas con VIH con lipodistrofia

    Directory of Open Access Journals (Sweden)

    H. Siqueira Vassimon

    2011-06-01

    Full Text Available Introduction: Human immunodeficiency vírus (HIV-associated lipodystrophy syndrome (LS includes body composition and metabolic alterations. Lack of validated criteria and tools make difficult to evaluate body composition in this group. Objective: The aim of the study was to compare different methods to evaluate body composition between Brazilians HIV subjects with (HIV+LIPO+ or without LS (HIV+LIPO- and healthy subjects (Control. Methods: in a cross-sectional analyses, body composition was measured by bioelectrical impedance analysis (BIA, skinfold thickness (SF and dual-energy x-ray absorptiometry (DXA in 10 subjects from HIV+LIPO+ group; 22 subjects from HIV+LIPO- group and 12 from Control group. Results: There were no differences in age and body mass index (BMI between groups. The fat mass (FM (% estimated by SF did not correlate with DXA in HIV+LIPO+ group (r = 0,46/ p > 0,05 and had fair agreement in both HIV groups (HIV+LIPO+ =0,35/ HIV+ LIPO- = 0,40. BIA had significant correlation in all groups (p Introducción: El síndrome de lipodistrofia (SL asociado al virus de inmunodeficiencia humana (HIV incluye alteraciones en la composición corporal y metabólica. La falta de herramientas adecuadas y criterios válidos dificultan la evaluación de la composición corporal en este grupo. Objetivo: El objetivo del estudio fue comparar distintos métodos para evaluar la composición corporal entre individuos brasileños con HIV que teniam (HIV+LIPO+ o no LS (HIV+LIPO- e individuos sanos (control. Métodos: Estudio transversal en el que fue evaluada la composición corporal por análisis de impedancia bioeléctrica (BIA, pliegues cutáneos (SF y absorciometría de rayos X de doble energía (DXA en un grupo de 10 individuos con HIV+LIPO+, 22 individuos del grupo HIV+ LIPO- y 12 individuos del grupo control. Resultados: No hubo diferencias en la edad e índice de masa corporal (IMC entre grupos. La masa grasa (MG (% estimada por SF no se correlacion

  17. Generation of Bio-electricity by Microbial Fuel Cells

    Directory of Open Access Journals (Sweden)

    Maksudur R. Khan

    2012-06-01

    Full Text Available Renewable energy is an increasing need in our society. Microbial fuel cell (MFC technology represents a new technology for the regeneration of electricity from what would otherwise be considered waste and can be a vital candidate for energy in this respect. Electricity directly generated by using bacteria while accomplishing wastewater treatment in MFC processes. The present study deals with performance of proton exchange membrane and cation exchange resin for ion transfer. The effect of dimension of Resin Bridge on electricity generation and COD removal was reported. A maximum voltage of 10.5 mV was observed at 400ppm of KMnO4 along with 400ml of dairy in an anode chamber. Average COD removal was in the range of 70% to 90%.

  18. Conductive polymer combined silk fiber bundle for bioelectrical signal recording.

    Directory of Open Access Journals (Sweden)

    Shingo Tsukada

    Full Text Available Electrode materials for recording biomedical signals, such as electrocardiography (ECG, electroencephalography (EEG and evoked potentials data, are expected to be soft, hydrophilic and electroconductive to minimize the stress imposed on living tissue, especially during long-term monitoring. We have developed and characterized string-shaped electrodes made from conductive polymer with silk fiber bundles (thread, which offer a new biocompatible stress free interface with living tissue in both wet and dry conditions.An electroconductive polyelectrolyte, poly(3,4-ethylenedioxythiophene-poly(styrenesulfonate (PEDOT-PSS was electrochemically combined with silk thread made from natural Bombyx mori. The polymer composite 280 µm thread exhibited a conductivity of 0.00117 S/cm (which corresponds to a DC resistance of 2.62 Mohm/cm. The addition of glycerol to the PEDOT-PSS silk thread improved the conductivity to 0.102 S/cm (20.6 kohm/cm. The wettability of PEDOT-PSS was controlled with glycerol, which improved its durability in water and washing cycles. The glycerol treated PEDOT-PSS silk thread showed a tensile strength of 1000 cN in both wet and dry states. Without using any electrolytes, pastes or solutions, the thread directly collects electrical signals from living tissue and transmits them through metal cables. ECG, EEG, and sensory evoked potential (SEP signals were recorded from experimental animals by using this thread placed on the skin. PEDOT-PSS silk glycerol composite thread offers a new class of biocompatible electrodes in the field of biomedical and health promotion that does not induce stress in the subjects.

  19. Bioelectric potentials in the soil-plant system

    Science.gov (United States)

    Pozdnyakov, A. I.

    2013-07-01

    A detailed study of the electric potentials in the soil-plant system was performed. It was found that the electric potential depends on the plant species and the soil properties. A theoretical interpretation of the obtained data was given. All the plants, independently from their species and their state, always had a negative electric potential relative to the soil. The electric potential of the herbaceous plants largely depended on the leaf area. In some plants, such as burdock ( Arctium lappa) and hogweed ( Heracleum sosnowskyi), the absolute values of the negative electric potential exceeded 100 mV. The electric potential was clearly differentiated by the plant organs: in the flowers, it was lower than in the leaves; in the leaves, it was usually lower than in the leaf rosettes and stems. The electric potentials displayed seasonal dynamics. As a rule, the higher the soil water content, the lower the electric potential of the plants. However, an inverse relationship was observed for dandelions ( Taraxacum officinale). It can be supposed that the electric potential between the soil and the plant characterizes the vital energy of the plant.

  20. BIOELECTRIC EFFECTS OF QUININE ON POLARIZED AIRWAY EPITHELIAL CELLS

    OpenAIRE

    Rowe, Steven M.; Bates, Eleanor; Miller, Stacey; Alexander, Mariah; Mazur, Marina; Fortenberry, James A.; Bebok, Zsuzsa; Sorscher, Eric J.

    2007-01-01

    Quinine has been increasingly utilized as a placebo in cystic fibrosis (CF) clinical trials, including those leading to FDA approval of inhaled tobramycin, recent studies of anti-inflammatory aerosols such as glutathione, and clinical testing of hypertonic saline aerosols to augment mucous clearance. The drug effectively masks taste of experimental therapeutics, but could also confer changes in processes contributing to CF pathogenesis, including chloride secretion and paracellular ion permea...

  1. Use of electrocardiogram (ECG) electrodes for Bioelectrical Impedance Analysis (BIA)

    International Nuclear Information System (INIS)

    BIA is a safe, noninvasive, portable and relatively inexpensive method of estimating body composition that is practical and suitable for individual use and large-scale studies. However, the cost of the electrodes recommended by some BIA manufacturers is too high for developing countries; where very often the long and complicated process of importation reduces the time they can be used. The purpose of this study was to evaluate the use of two types of ECG electrodes (2290 and 2228 by 3M®) in BIA measurements to decrease the costs of the test. The results showed that the 2228 ECG electrodes can be used in BIA measurements for adult's body composition assessment. These electrodes are available in the domestic market and their costs are 92% lower than the electrodes recommended by manufacturer. The results show a new cost-benefit relation for BIA method and make this a more accessible tool for individual tests, large-scale researches and studies in the community.

  2. Bioelectric characterization of epithelia from neonatal CFTR knockout ferrets

    NARCIS (Netherlands)

    J.T. Fisher (John); S.R. Tyler (Scott); Y. Zhang (Yulong); B.J. Lee (Ben); X. Liu (Xiaoming); X. Sun (Xinying); H. Sui (Hongshu); B. Liang (Bo); M. Luo (Ma); W. Xie (Weiliang); I. Yi (Iasson); W. Zhou (Weili); Y. Song (Yiqing); N. Keiser (Nicholas); K. Wang (Kai); H.R. de Jonge (Hugo); J.F. Engelhardt (John)

    2013-01-01

    textabstractCystic fibrosis (CF) is a life-shortening, recessive, multiorgan genetic disorder caused by the loss of CF transmembrane conductance regulator (CFTR) chloride channel function found in many types of epithelia. Animal models that recapitulate the human disease phenotype are critical to un

  3. Conductive Polymer Combined Silk Fiber Bundle for Bioelectrical Signal Recording

    OpenAIRE

    Shingo Tsukada; Hiroshi Nakashima; Keiichi Torimitsu

    2012-01-01

    Electrode materials for recording biomedical signals, such as electrocardiography (ECG), electroencephalography (EEG) and evoked potentials data, are expected to be soft, hydrophilic and electroconductive to minimize the stress imposed on living tissue, especially during long-term monitoring. We have developed and characterized string-shaped electrodes made from conductive polymer with silk fiber bundles (thread), which offer a new biocompatible stress free interface with living tissue in bot...

  4. Modeling & imaging of bioelectrical activity principles and applications

    CERN Document Server

    He, Bin

    2010-01-01

    Over the past several decades, much progress has been made in understanding the mechanisms of electrical activity in biological tissues and systems, and for developing non-invasive functional imaging technologies to aid clinical diagnosis of dysfunction in the human body. The book will provide full basic coverage of the fundamentals of modeling of electrical activity in various human organs, such as heart and brain. It will include details of bioelectromagnetic measurements and source imaging technologies, as well as biomedical applications. The book will review the latest trends in

  5. Establishment of muscle mass diagnostic standard of sarcopenia using a bioelectrical impedance analysis and epidemiological investigation of the elderly in Shanghai%上海地区老年人肌少症骨骼肌质量诊断标准建立和流行病学调查

    Institute of Scientific and Technical Information of China (English)

    陈敏; 白慧婧; 王纯; 王彦; 徐丹凤; 谢华; 易青; 李臻; 李茹

    2015-01-01

    目的 应用生物电阻抗法(BIA)建立上海地区老年人肌少症骨骼肌质量诊断标准并开展上海地区老年人肌少症患病率的调查.方法 对40例志愿者(年龄20~77岁)进行BIA和双能X线吸收仪(DEXA)检测,验证BIA测定瘦体组织的可靠性.对219例(年龄20~40岁)健康青年人(男∶女为100∶119)进行BIA检测,获得峰值肌量和老年人肌少症诊断切点.对657例≥60岁医院体检和社区老年人(男∶女为318∶339)进行BIA检测,了解上海地区老年人肌少症患病率.结果 BIA和DEXA检测瘦体组织差异无统计学意义(P=0.307).健康青年人四肢肌肉组织和身高平方的比值(ASM/身高2)男性和女性分别为(7.90±0.62)kg/m2和(6.12±0.44)kg/m2,老年人肌少症诊断标准男性和女性分别为≤6.66 kg/m2和≤5.24 kg/m2.将老年人分为3个年龄段,60~岁、70~岁和≥80岁3个年龄段男性肌少症的患病率分别为14.6%、25.0%和36.0%,女性分别为6.8%、12.6%和27.9%.老年男性整体患病率为23.6%,女性为11.8%.结论 BIA检测人体肌肉组织是可靠的,且随增龄肌少症患病率明显上升,男性高于女性.%Objective To establish diagnostic standard of sarcopenia using bioelectrical impedance analysis (BIA) and to obtain the prevalence of sarcopenia in the elderly in Shanghai.Methods 40 volunteers aged 20-77 years were enrolled and received BIA and dual-energy X-ray absorptiometry (DEXA) measurements in order to verify the reliability of BIA for measuring lean mass.219 healthy young volunteers aged 20 to 40 years with ratio of gender men:women 100:119 had BIA measurements to obtain peak muscle mass and sarcopenia diagnostic cut-off point of the elderly.657 elderly aged ≥ 60 years with ratio of gendermen:women 318:339 took BIA measurements to obtain the prevalence of sarcopenia in the elderly in Shanghai.Results No statistical difference between BIA-measured and DEXA-measured LM was observed (P =0.307).The

  6. 生物电阻抗法测量7~10岁儿童总体水含量和去脂体重的预测模型%A Bioelectrical Impedance Prediction Equation for the Assessment of Total Body Water and Fat-free Mass among Chinese Children Aged 7-10 Years

    Institute of Scientific and Technical Information of China (English)

    王晓君; 胡小琪; 徐海泉; 郭向晖; 李振英; 刘爱玲

    2011-01-01

    Objective To develop the bioelectrical impedance analysis (BIA) prediction equation for the assessment of body composition among Chinese children. Methods A total of 409 children (220 boys, 189 girls) aged 7-10 years were recruited in Beijing. Body height, weight, resistance and reactance measured by BIA were collected. Total body water (TBW) and fat-free mass (FFM) measured by deuterium dilution technique was used as reference. The multiple stepwise regression analysis was employed to set up equations. Pure error (PE) and Bland-Altman approach was used to cross-validate the prediction equations. Results The prediction equation for TBW was: -6.893 + 0.410xgender(boy=l, girl=0)+0.273xage(year)+0.174xweight(kg) + 0.081 xheight(cm)+ 0.206xRI (cmVft) [R2=0.90, root mean square error (RMSE) = 1.2 kg ], and for FFM was: -9.742 +0.784x gender (boy=l, girl=0)+0.429xage(year)+0.227xweight (kg)+0.104xheight (cm) + 0.269xRI(cm2/fi) (/?2=0.90, RMSE=1.6 kg). No significant difference between predicted TBW,FFM and measured TBW,FFM was found. PE was 1.4 and 1.8 kg for TBW equation and FFM equation, respectively. However, the mean of predicted and measured TBW,FFM correlated positively with the difference between the predicted and measured values ( correlation coefficient 0.24 for TBW and 0.23 for FFM,P<0.01). The two equations performed well in different BMI groups. Conclusion The developed BIA prediction equations for the estimation of TBW and FFM have a high accuracy and precision and are valid for the assessment of body composition among Chinese children aged 7-10 years.%目的 利用生物电阻抗方法测量儿童的体成分,建立适合我国儿童体成分的预测方程.方法 在北京市采用目的抽样法选取409名7~10岁的儿童(男生220名,女生189名),测量身高和体重,采用生物电阻抗仪测量全身电阻抗和电容抗,采用单标水法测量的总体水(total body water,TBW)和去脂体重(fat-free mass,FFM)作为标准,用多元线性逐步

  7. Interrelationship of the muscle mass and muscle strength of students in late puberty and speed of sound detected by quantitative ultrasound method and bioelectrical impedance method%定量超声法和生物电阻抗法测定青春发育后期学生肌肉量、肌力与跟骨超声传导速度的相互关系

    Institute of Scientific and Technical Information of China (English)

    李成明; 张伟

    2012-01-01

    BACKGROUND: Studies addressing the relation of student's body composition and bone mineral density in late puberty are rare. OBJECTIVE: To explore the relationship of physical fitness and body composition of students in the late youth with the speed of sound (SOS). METHODS: Quantitative ultrasound and bio-electrical impedance methods were applied in 1 004 students aged 17-20 years. RESULTS AND CONCLUSION: The physique and body composition of body students were significantly better than those of girl students. Students with different degrees of obesity had obvious physical changes: the higher the fat percentage, the worse the physical fitness. Fat percentage, muscle mass and muscle strength had a significant linear relationship with the SOS. These findings show that a clear gender difference exists between the physical fitness and body composition, but there is no gender difference in the SOS; students with different degrees of obesity has obvious physical differences, and the fat percentage in the normal range indicates the good physical fitness of students; the fat percentage is negatively correlated to the SOS, and the higher the fat percentage, the lower the bone mineral density that is influenced by muscle strength and muscle mass.%背景:查阅国内外研究文献发现研究青春发育后期学生体成分与骨密度的文章很少.目的:探讨处于青春后期的学生体质、体成分与跟骨超声传导速度的相互关系.方法:采用定量超声法和生物电阻抗法对在校的1 004名17~20周岁的学生进行了测试.结果与结论:男生的体质和体成分明显好于女生;肥胖度不同的学生,体质具有明显的层次变化,脂肪百分比越高则体质越差;脂肪百分比、肌肉量和肌力与跟骨超声传导速度具有显著的线性关系.结果可见体质和体成分具有明显的性别差异,但跟骨超声传导速度没有性别差异;肥胖度不同的学生体质具有明显的差异性,脂肪百分比处在

  8. Use of bioelectrical impedance analysis to assess body composition in rural Gambian children

    NARCIS (Netherlands)

    Prins, M.; Hawkesworth, S.; Wright, A.; Fulford, A.J.C.; Jarjou, L.M.A.; Prentice, A.M.; Moore, S.E.

    2008-01-01

    Objective: To validate the Tanita BC-418MA Segmental Body Composition Analyser and four-site skinfold measurements for the prediction of total body water (TBW), percentage fat-free mass (% FFM) and percentage body fat (%BF) in a population of rural Gambian children. Subjects/Methods: One hundred and

  9. Bioelectricity Generation in a Microbial Fuel Cell with a Self-Sustainable Photocathode

    Directory of Open Access Journals (Sweden)

    Ting Liu

    2015-01-01

    Full Text Available This study aims to construct an MFC with a photosynthetic algae cathode, which is maintained by self-capturing CO2 released from the anode and utilizing solar energy as energy input. With this system, a maximum power density of 187 mW/m2 is generated when the anode off gas is piped into the catholyte under light illumination, which is higher than that of 21 mW/m2 in the dark, demonstrating the vital contribution of the algal photosynthesis. However, an unexpected maximum power density of 146 mW/m2 is achieved when the anode off gas is not piped into the catholyte. Measurements of cathodic microenvironments reveal that algal photosynthesis still takes place for oxygen production under this condition, suggesting the occurrence of CO2 crossover from anode to cathode through the Nafion membrane. The results of this study provide further understanding of the algae-based microbial carbon capture cell (MCC and are helpful in improving MCC performance.

  10. Conversion of wastes into bioelectricity and chemicals by using microbial electrochemical technologies.

    Science.gov (United States)

    Logan, Bruce E; Rabaey, Korneel

    2012-08-10

    Waste biomass is a cheap and relatively abundant source of electrons for microbes capable of producing electrical current outside the cell. Rapidly developing microbial electrochemical technologies, such as microbial fuel cells, are part of a diverse platform of future sustainable energy and chemical production technologies. We review the key advances that will enable the use of exoelectrogenic microorganisms to generate biofuels, hydrogen gas, methane, and other valuable inorganic and organic chemicals. Moreover, we examine the key challenges for implementing these systems and compare them to similar renewable energy technologies. Although commercial development is already underway in several different applications, ranging from wastewater treatment to industrial chemical production, further research is needed regarding efficiency, scalability, system lifetimes, and reliability. PMID:22879507

  11. Myocardial remodeling and bioelectric changes in tachycardia-induced heart failure in dogs

    Energy Technology Data Exchange (ETDEWEB)

    Song, B.; Wang, B.N.; Chen, D.N.; Luo, Z.G. [Department of Cardiovascular Medicine, The First Affiliated Hospital, Anhui Medical University, HeFei, Anhui Province (China)

    2013-09-06

    In this study, electrical and structural remodeling of ventricles was examined in tachycardia-induced heart failure (HF). We studied two groups of weight-matched adult male mongrel dogs: a sham-operated control group (n=5) and a pacing group (n=5) that underwent ventricular pacing at 230 bpm for 3 weeks. Clinical symptoms of congestive HF were observed in both groups. Their hemodynamic parameters were determined and the severity of the HF was evaluated by M-mode echocardiography. Changes in heart morphology were observed by scanning electron and light microscopy. Ventricular action potential duration (APD), as well as the 50 and 90% APD were measured in both groups. All dogs exhibited clinical symptoms of congestive HF after rapid right ventricular pacing for 3 weeks. These data indicate that rapid, right ventricular pacing produces a useful experimental model of low-output HF in dogs, characterized by biventricular pump dysfunction, biventricular cardiac dilation, and non-ischemic impairment of left ventricular contractility. Electrical and structural myocardial remodeling play an essential role in congestive HF progression, and should thus be prevented.

  12. EFFECTS OF FOOD AND DRINK INGESTION ON BODY COMPOSITION VARIABLES OF ABDOMINAL BIOELECTRICAL IMPEDANCE.

    Science.gov (United States)

    Fernández Vázquez, Rosalía; Martínez Blanco, Javier; García Vega, María del Mar; Barbancho, Miguel Ángel; Alvero-Cruz, José Ramón

    2015-11-01

    Objetivo: conocer los cambios en la grasa del tronco y el nivel de grasa visceral determinado por BIA abdominal, así como otras medidas antropométricas relacionadas con la grasa abdominal o central después de la ingestión de una comida. Métodos: se realizó un protocolo experimental para evaluar un estudio descriptivo de intervención longitudinal. Los participantes fueron 21 sujetos (10 hombres y 11 mujeres), voluntarios que tuvieron acceso a una evaluación médica, con una edad de 74 años ± 13,43. Las mediciones antropométricas fueron: circunferencia de la cintura máxima en posición de pie, circunferencia de la cintura a nivel del ombligo en posición de decúbito supino y diámetro sagital abdominal (SAD). Además se obtuvo la grasa del tronco y el nivel de grasa visceral, por análisis de impedancia bioeléctrica abdominal, con un dispositivo Tanita AB-140 (ViScan), todo ello antes y después de una ración de comida. Resultados: las medidas antropométricas, como la circunferencia de la cintura en posición supina y SAD, no mostraron diferencias significativas (P > 0,05), después de la ingestión de alimentos, a excepción de un aumento significativo de la circunferencia de la cintura máxima en posición de pie (P 0,05). Los cambios porcentuales de las medidas fueron menores del 2% para la circunferencia de la cintura en posición de pie, para la circunferencia de cintura por Viscan, para el diámetro sagital abdominal y la grasa del tronco, y un 5,9% para el nivel de grasa visceral. Conclusiones: los efectos de una comida y bebida sobre la grasa del tronco y el nivel de grasa visceral, medidas por impedancia bioeléctrica abdominal, son mínimas, aunque siempre es recomendable hacerlo en condiciones de ayuno.

  13. Development of three-dimension microelectrode array for bioelectric measurement using the liquidmetal-micromolding technique

    International Nuclear Information System (INIS)

    A method of manufacturing three-dimension microneedle electrode arrays is presented in this paper using the micromolding technology with liquid metal at room temperature, based on the physical property of the Bi-In-Sn liquid metal alloy, being its melting point especially low. Observed under scanning electron microscopy, the needle body of the electrode chip manufactured using this method has a good consistency. Skin penetration test in-vitro indicates that the microneedle electrode can pierce the stratum corneum and cross the high-impedance layer to acquire electrical signals. Electrical impedance and polarization voltage experimental results show that the electrode chips have great electric characteristics and meet the practical application demands

  14. Sensitivity field distributions for segmental bioelectrical impedance analysis based on real human anatomy

    International Nuclear Information System (INIS)

    In this work, an adaptive unstructured tetrahedral mesh generation technology is applied for simulation of segmental bioimpedance measurements using high-resolution whole-body model of the Visible Human Project man. Sensitivity field distributions for a conventional tetrapolar, as well as eight- and ten-electrode measurement configurations are obtained. Based on the ten-electrode configuration, we suggest an algorithm for monitoring changes in the upper lung area.

  15. The discovery of antidepressant drugs by computer-analyzed human cerebral bio-electrical potentials (CEEG).

    Science.gov (United States)

    Itil, T M

    1983-01-01

    Antidepressant properties of six compounds were predicted based on their computer-analyzed human electroencephalographical (CEEG) profiles. The clinical investigations with mianserin (GB-94) confirmed the CEEG prediction. This compound has now been marketed as the first antidepressant of which the clinical effects were discovered solely by the quantitative pharmaco-EEG method. As predicted by the CEEG, clinical antidepressant properties of GC-46, mesterolone, and estradiol valerate were observed in preliminary investigations. No extensive studies with definite statistical results were yet carried out with these compounds. No systematic large studies could be conducted with cyclozocine and cyproterone acetate because of the intolerable side effects with these compounds. The optical isomers of mianserin, GF-59 and GF-60, both predicted as antidepressant by the computer EEG data base, have not yet been tested in depressive patients. None of these compounds possess the "typical" pharmacological and/or biochemical profiles of marketed antidepressants. Thus, the discovery of the established antidepressant properties of mianserin (GB-94) by computer analyzed EEG method challenges the well-known biochemical hypotheses of depression and the "classical" development of antidepressant drugs. PMID:6142498

  16. CONSTRUCTION OF AGAR SALT BRIDGE MICROBIAL FUEL CELL (MFC) AND BIOELECTRICITY PRODUCTION FROM WASTE

    OpenAIRE

    Gowramma Buddolla; Chamundeswari Kanneluri Vijaya; Arun kumar Jadguru Matt

    2015-01-01

    In the current study MFC were constructed using PVC Schedule Tee, PVC Schedule Connector, PVC Schedule Slip Cap, Titanium fishing lead, Clear plastic wrap, Rubber bands, Salt Bridge Medium (Sodium chloride, Agar and Water). It mainly consists of anode and cathode chamber connecte dtoa multimeter to complete the circuit. Wires and carbon brushes were us ed to ma ke the c a rbon electrodes. Four different waste water samples were (Stagnant waste water, Dairy waste, Liquid waste c...

  17. Development of NPP control room operators's mental workload measurement system using bioelectric signals

    International Nuclear Information System (INIS)

    This study developed mentalload measurement system based on the relations between mentalload and physiological responses of the human operators. The measurement system was composed of the telemetry system for EEG, EOG, ECG and respiration pattern of the subjects, A/D converter, the physiological signal processing programs (compiled by the Labview). The signal processing programs transformed the physiological signal into the scores indicating mentalload status of the subjects and recorded the mentalload scores in the form of the table of a database. The acqknowledge and the labview programs additionally transformed the mentalload score database and the operator behavior database so that both database were consolidated into one. 94 figs., 57 refs. (Author)

  18. Bioelectrical impedance analysis (BIA) for sarcopenic obesity (SO) diagnosis in young female subjects

    International Nuclear Information System (INIS)

    Sarcopenia is defined as a loss of muscle mass depending of ageing and affecting physical function (definition A). A new definition considers excluding mass reduction criterion (definition B). Obesity is pandemic and occurs at all ages. Sarcopenic obesity (SO) implies both processes. The purpose of this study was to compare the results obtained after applying these 2 definitions in 66 aged 22 ± 2.8 years overweight or obese young college women. Percentage body fat (%BF) and skeletal mass index (SMI) were estimated by BIA, muscle function by handgrip strength test (HGS) and physical performance by Harvard step test (HST). There were 9.1% and 90.9% overweight or obese subjects. Twenty nine subjects (43.9%) had decreased HGS and 22 (33.3%) had impaired physical performance. One obese subject (1.5%) met the criteria for sarcopenic obesity by definition A and 9 (13.6%) by definition B. Although a linear regression (α 2 = 0.094, 0.037 and 0.275 respectively) it was observed a tendency for HGS, HST and SMI deterioration when %BF increases. However, other confounding factors must be investigated. Probably as the population gets more obese, the problematic of SO will be found earlier in life.

  19. A comparative analysis of printing techniques by using an active concentric ring electrode for bioelectrical recording

    OpenAIRE

    García Breijo, Eduardo; Prats Boluda, Gema; Lidon-Roger, Jose V.; Ye Lin, Yiyao; Garcia Casado, Francisco Javier

    2015-01-01

    Purpose This paper aims to present a comparison between three types of manufacturing techniques, namely, screen-printed, inkjet and gravure, using different types of inks, for the implementation of concentric ring electrodes which permit estimation of Laplacian potential on the body surface. Design/methodology/approach Flexible concentric ring electrodes not only present lower skin electrode contact impedance and lower baseline wander than rigid electrodes but are also less sens...

  20. Single-cell bioelectrical impedance platform for monitoring cellular response to drug treatment

    OpenAIRE

    Asphahani, Fareid; Wang, Kui; Thein, Myo; Veiseh, Omid; Yung, Sandy; Xu, Jian; Zhang, Miqin

    2011-01-01

    The response of cells to a chemical or biological agent in terms of their impedance changes in real-time is a useful mechanism that can be utilized for a wide variety of biomedical and environmental applications. The use of a single-cell based analytical platform could be an effective approach to acquiring more sensitive cell impedance measurements, particularly in applications where only diminutive changes in impedance are expected. Here, we report the development of an on-chip cell impedanc...

  1. Development of NPP control room operators`s mental workload measurement system using bioelectric signals

    Energy Technology Data Exchange (ETDEWEB)

    Shim, Bong Sik; Oh, In Seok; Lee, Hyun Cheol; Cha, Kyung Ho [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of); Lee, Dong Ha [Suwon Univ., Suwon (Korea, Republic of)

    1996-09-01

    This study developed mentalload measurement system based on the relations between mentalload and physiological responses of the human operators. The measurement system was composed of the telemetry system for EEG, EOG, ECG and respiration pattern of the subjects, A/D converter, the physiological signal processing programs (compiled by the Labview). The signal processing programs transformed the physiological signal into the scores indicating mentalload status of the subjects and recorded the mentalload scores in the form of the table of a database. The acqknowledge and the labview programs additionally transformed the mentalload score database and the operator behavior database so that both database were consolidated into one. 94 figs., 57 refs. (Author).

  2. Bioelectric Activity in the Suprachiasmatic Nucleus—Pineal Gland System in Children with Adolescent Idiopathic Scoliosis

    OpenAIRE

    Dmitry Yu Pinchuk; Bekshaev, Sergey S.; Bumakova, Svetlana A.; Dudin, Mikhail G.; Pinchuk, Olga D.

    2012-01-01

    The purpose of this work is to identify a role of the pineal gland/suprachiasmatic nucleus system in adolescent idiopathic scoliosis (AIS) aetiology and pathogenesis. To analyze electroencephalograms of 292 children with AIS and in 46 healthy subjects, a processing method was used to assess three-dimensional coordinates of electric equivalent dipole sources (EEDSs) within the brain. Amounts of EEDSs in the pineal gland and suprachiasmatic nucleus (SCN) area were assessed in different age grou...

  3. Body composition of Bangladeshi children: comparison and development of leg-to-leg bioelectrical impedance equation.

    Science.gov (United States)

    Khan, Ashraful I; Hawkesworth, Sophie; Hawlader, Mohammad Delwer Hossain; El Arifeen, Shams; Moore, Sophie; Hills, Andrew P; Wells, Jonathan C; Persson, Lars-Åke; Kabir, Iqbal

    2012-09-01

    The aim of this study was to investigate the validity of the Tanita TBF 300A leg-to-leg bioimpedance analyzer for estimating fat-free mass (FFM) in Bangladeshi children aged 4-10 years and to develop novel prediction equations for use in this population, using deuterium dilution as the reference method. Two hundred Bangladeshi children were enrolled. The isotope dilution technique with deuterium oxide was used for estimation of total body water (TBW). FFM estimated by Tanita was compared with results of deuterium oxide dilution technique. Novel prediction equations were created for estimating FFM, using linear regression models, fitting child's height and impedance as predictors. There was a significant difference in FFM and percentage of body fat (BF%) between methods (pmodel with height and impedance explained 83% of the variance in FFM estimated by deuterium oxide dilution technique. The best-fit equation to predict FFM from linear regression modelling was achieved by adding weight, sex, and age to the basic model, bringing the adjusted R² to 89% (standard error=0.90, p<0.001). These data suggest Tanita analyzer may be a valid field-assessment technique in Bangladeshi children when using population-specific prediction equations, such as the ones developed here.

  4. [ABDOMINAL BIOELECTRICAL IMPEDANCE ANALYSIS AND ANTHROPOMETRY FOR PREDICTING METABOLIC SYNDROME IN MIDDLE AGED MEN].

    Science.gov (United States)

    Fernández-Vázquez, Rosalía; Millán Romero, Ángel; Barbancho, Miguel Ángel; Alvero-Cruz, José Ramón

    2015-09-01

    Objetivo: la obesidad central tiene una gran relación con el síndrome metabólico. Estudiar la relación de la grasa del tronco, el índice de grasa visceral y las medidas antropométricas con el síndrome metabólico. Métodos: diseño: transversal descriptivo y correlacional. Participaron 75 varones, voluntarios, de distintas profesiones, que accedieron a un reconocimiento médico- laboral, con un rango de edad de 21 a 59 años. Mediciones de peso, talla, índice de masa corporal, perímetro abdominal, perímetro glúteo, índice cintura-cadera y grasa de tronco y nivel de grasa visceral mediante bioimpedanciometría (Tanita AB-140-ViScan) y parámetros bioquímicos: glucosa, colesterol total y triglicéridos. Así mismo, se midió la presión arterial sistólica y diastólica. Se comparan los estados de síndrome metabólico, sobrepeso y obesidad. Resultados: existen correlaciones de las medidas antropométricas con la de grasa de tronco y el nivel de grasa visceral, así como con los parámetros bioquímicos (p < 0,001). Un análisis de curvas ROC muestra que los puntos de corte a partir de los cuales se puede presentar el síndrome metabólico son de 32,7% de grasa de tronco y de 13 para el nivel de grasa visceral, con una alta sensibilidad y especificidad. Se obtienen los mismos puntos de corte para el estado de obesidad y síndrome metabólico. Conclusiones: la grasa de tronco y los niveles de grasa visceral son muy sensibles y específicos para la detección del síndrome metabólico y la obesidad, aunque no superan a las variables e índices antropométricos. En la condición de sobrepeso, la grasa de tronco y visceral son medidas algo más predictivas que las variables antropométricas.

  5. The influence of the run intensity on bioelectrical activity of selected human leg muscles.

    Science.gov (United States)

    Mastalerz, Andrzej; Gwarek, Lucyna; Sadowski, Jerzy; Szczepański, Tadeusz

    2012-01-01

    The purpose of this work was to investigate the electromyographic (EMG) fatigue representations in muscles of male runners during run at different level of intensity. In this study, the EMG signals for the rectus femoris and biceps femoris (long head) were collected by bipolar electrodes from the left and right lower extremities. EMG measurements were recorded during the run on tartan athletic track. Four professional athletes had to run a 400 m distance with a different intensity. The first distance of 400 m took 90 s; the second, 70 s; the third, 60 s; and the last one was covered with a maximal velocity until exhaustion. Power spectral analysis of EMG signals was carried out to calculate MPF. The results of our study revealed the efforts of different intensity for each muscle individually. The effect of fatigue was observed only in the case of running with the highest velocity. The biggest changes in MPF were observed for BF (23.6%) and RF (19.5%) muscles of the left leg and then for BF (17.5%) and RF (12.5%) ones of the right leg. We supposed that those differences between the right and left legs were mainly due to the curve of the track where those muscles are differently loaded.

  6. Malnutrition in remission of childhood cancers as assessed by bioelectric impedance analysis

    Directory of Open Access Journals (Sweden)

    M. V. Konovalova

    2012-01-01

    Full Text Available The results of our cross-sectional bioimpedance study of children aged 7–17 years cured of cancer during follow-up (patients’ group, n = 552, remission time range 0–15 years and of age-matched healthy controls (n = 1,500 show significant intergroup differences in body height and body composition parameters. The most pronounced alterations in the patients’ group were observed in standardized values of phase angle reflecting a sharp decrease in the percentage of metabolically active body cell mass in fat-free mass. Malnutrition, judged from the prevalence of obesity and low phase angle, was observed in 52.7 % of our patients reaching a maximum of 76.8 % in a subgroup of children with CNS tumors. In view of known association that exists between malnutrition and reduced tolerance to chemotherapy, increased susceptibility to infections and adverse outcomes rate, we recommend using bioimpedance analysis in remission of childhood cancers in order to monitoring and timely correction of nutritional state as well as for prevention of delayed cardiovascular risks.

  7. Malnutrition in remission of childhood cancers as assessed by bioelectric impedance analysis

    Directory of Open Access Journals (Sweden)

    M. V. Konovalova

    2014-07-01

    Full Text Available The results of our cross-sectional bioimpedance study of children aged 7–17 years cured of cancer during follow-up (patients’ group, n = 552, remission time range 0–15 years and of age-matched healthy controls (n = 1,500 show significant intergroup differences in body height and body composition parameters. The most pronounced alterations in the patients’ group were observed in standardized values of phase angle reflecting a sharp decrease in the percentage of metabolically active body cell mass in fat-free mass. Malnutrition, judged from the prevalence of obesity and low phase angle, was observed in 52.7 % of our patients reaching a maximum of 76.8 % in a subgroup of children with CNS tumors. In view of known association that exists between malnutrition and reduced tolerance to chemotherapy, increased susceptibility to infections and adverse outcomes rate, we recommend using bioimpedance analysis in remission of childhood cancers in order to monitoring and timely correction of nutritional state as well as for prevention of delayed cardiovascular risks.

  8. Measurement errors in multifrequency bioelectrical impedance analyzers with and without impedance electrode mismatch.

    OpenAIRE

    Bogónez Franco, Francisco; Nescolarde Selva, Lexa Digna; Bragós Bardia, Ramon; Rosell Ferrer, Francisco Javier; Yandiola, Iñigo

    2009-01-01

    The purpose of this study is to compare measurement errors in two commercially available multi-frequency bioimpedance analyzers, a Xitron 4000B and an ImpediMed SFB7, including electrode impedance mismatch. The comparison was made using resistive electrical models and in ten human volunteers. We used three different electrical models simulating three different body segments: the right-side, leg and thorax. In the electrical models, we tested the effect of the capacitive coupling of the ...

  9. Comparison of body fat in Brazilian adult females by bioelectrical impedance analysis

    Science.gov (United States)

    Altamir, Vaz; Frère, Slaets Annie France; Ramírez Leonardo, López

    2012-12-01

    Body-fat is essential for human body, provided that its amount is at healthy levels. If in-excess body-fat is deleterious, its lack is otherwise also harmful. Estimated percent body-fat performed with commercially available devices measuring bioimpedance have many advantages, such as easy measurement and low cost. However, these measurements are based on standard models and equations that are not disclosed by manufacturers, and this leads to questioning the validity of these estimates for Brazilian females. The aim of this study was to compare electrical tetrapolar and octapolar impedance results obtained with commercially available equipment: Maltron BF-906 and OMRON 510-W. Data analysis involved descriptive and inferential statistics. Devices used in this study to estimate body fat quantity have not shown any significant differences in results; this is a major issue when selecting equipment based on three factors: study focus, available financial resources, and target population. Results obtained from the two devices have not shown any significant differences, which lead to the conclusion that either device may be reliably used.

  10. Pengembangan Bioelectrical Impedance Sebagai Control Commands Pengaturan Kecepatan Gerak Kursi Roda Dengan Metoda PID Controller

    OpenAIRE

    Juli Sardi; Ali Basrah Pulungan

    2014-01-01

    In the present study, bioimpedance signals of human body was utilized to control speed of a wheelchair movement. A bioimpedance is electrically passive part contained the body tissues. The research is one of alternative solutions for patients with paralysis of the upper and lower limb. Firstly, design of system of the research consisted of bioimpedance measuring instruments and a mechanical design of the wheelchair. Bioimpedance measurement was performed by injecting a sinusoidal current sour...

  11. Bioelectrical impedance analysis (BIA): a proposal for standardization of the classical method in adults

    International Nuclear Information System (INIS)

    The accuracy of BIA measurements is limited by different sources of error such as physical model, cross sectional area, ethnicity, body hydration, age and level of body fat among other variables. Equation for each population is required as they can produce overestimation when manufacturer's equations are used. The classical measurements hand to foot has shown better correlation against hydrodensitometry than foot to foot or hand to hand. However there is a lack for an accepted standard of BIA procedures. This is compounded when there is not a good report of the BIA study's methodology; hence the comparability between the results is poor and reduces the reliability of the method. Perhaps, standardization of methods would be the first step for BIA studies to move forward and subsequently improve its accuracy. Standardized procedures could also minimize the impact of these variables on studies results. The aim of this study was to propose a protocol as a checklist to standardize BIA procedures and produce comparable results from future studies performed with the classic hand-foot configuration in adults.

  12. Measurement errors in multifrequency bioelectrical impedance analyzers with and without impedance electrode mismatch

    International Nuclear Information System (INIS)

    The purpose of this study is to compare measurement errors in two commercially available multi-frequency bioimpedance analyzers, a Xitron 4000B and an ImpediMed SFB7, including electrode impedance mismatch. The comparison was made using resistive electrical models and in ten human volunteers. We used three different electrical models simulating three different body segments: the right-side, leg and thorax. In the electrical models, we tested the effect of the capacitive coupling of the patient to ground and the skin–electrode impedance mismatch. Results showed that both sets of equipment are optimized for right-side measurements and for moderate skin–electrode impedance mismatch. In right-side measurements with mismatch electrode, 4000B is more accurate than SFB7. When an electrode impedance mismatch was simulated, errors increased in both bioimpedance analyzers and the effect of the mismatch in the voltage detection leads was greater than that in current injection leads. For segments with lower impedance as the leg and thorax, SFB7 is more accurate than 4000B and also shows less dependence on electrode mismatch. In both devices, impedance measurements were not significantly affected (p > 0.05) by the capacitive coupling to ground

  13. Sensitivity field distributions for segmental bioelectrical impedance analysis based on real human anatomy

    Science.gov (United States)

    Danilov, A. A.; Kramarenko, V. K.; Nikolaev, D. V.; Rudnev, S. G.; Salamatova, V. Yu; Smirnov, A. V.; Vassilevski, Yu V.

    2013-04-01

    In this work, an adaptive unstructured tetrahedral mesh generation technology is applied for simulation of segmental bioimpedance measurements using high-resolution whole-body model of the Visible Human Project man. Sensitivity field distributions for a conventional tetrapolar, as well as eight- and ten-electrode measurement configurations are obtained. Based on the ten-electrode configuration, we suggest an algorithm for monitoring changes in the upper lung area.

  14. Kdm6b and Pmepa1 as Targets of Bioelectrically and Behaviorally Induced Activin A Signaling.

    Science.gov (United States)

    Link, Andrea S; Kurinna, Svitlana; Havlicek, Steven; Lehnert, Sandra; Reichel, Martin; Kornhuber, Johannes; Winner, Beate; Huth, Tobias; Zheng, Fang; Werner, Sabine; Alzheimer, Christian

    2016-08-01

    The transforming growth factor-β (TGF-β) family member activin A exerts multiple neurotrophic and protective effects in the brain. Activin also modulates cognitive functions and affective behavior and is a presumed target of antidepressant therapy. Despite its important role in the injured and intact brain, the mechanisms underlying activin effects in the CNS are still largely unknown. Our goal was to identify the first target genes of activin signaling in the hippocampus in vivo. Electroconvulsive seizures, a rodent model of electroconvulsive therapy in humans, were applied to C57BL/6J mice to elicit a strong increase in activin A signaling. Chromatin immunoprecipitation experiments with hippocampal lysates subsequently revealed that binding of SMAD2/3, the intracellular effectors of activin signaling, was significantly enriched at the Pmepa1 gene, which encodes a negative feedback regulator of TGF-β signaling in cancer cells, and at the Kdm6b gene, which encodes an epigenetic regulator promoting transcriptional plasticity. Underlining the significance of these findings, activin treatment also induced PMEPA1 and KDM6B expression in human forebrain neurons generated from embryonic stem cells suggesting interspecies conservation of activin effects in mammalian neurons. Importantly, physiological stimuli such as provided by environmental enrichment proved already sufficient to engender a rapid and significant induction of activin signaling concomitant with an upregulation of Pmepa1 and Kdm6b expression. Taken together, our study identified the first target genes of activin signaling in the brain. With the induction of Kdm6b expression, activin is likely to gain impact on a presumed epigenetic regulator of activity-dependent neuronal plasticity. PMID:26215835

  15. The discovery of antidepressant drugs by computer-analyzed human cerebral bio-electrical potentials (CEEG).

    Science.gov (United States)

    Itil, T M

    1983-01-01

    Antidepressant properties of six compounds were predicted based on their computer-analyzed human electroencephalographical (CEEG) profiles. The clinical investigations with mianserin (GB-94) confirmed the CEEG prediction. This compound has now been marketed as the first antidepressant of which the clinical effects were discovered solely by the quantitative pharmaco-EEG method. As predicted by the CEEG, clinical antidepressant properties of GC-46, mesterolone, and estradiol valerate were observed in preliminary investigations. No extensive studies with definite statistical results were yet carried out with these compounds. No systematic large studies could be conducted with cyclozocine and cyproterone acetate because of the intolerable side effects with these compounds. The optical isomers of mianserin, GF-59 and GF-60, both predicted as antidepressant by the computer EEG data base, have not yet been tested in depressive patients. None of these compounds possess the "typical" pharmacological and/or biochemical profiles of marketed antidepressants. Thus, the discovery of the established antidepressant properties of mianserin (GB-94) by computer analyzed EEG method challenges the well-known biochemical hypotheses of depression and the "classical" development of antidepressant drugs.

  16. Bioelectric signal classification using a recurrent probabilistic neural network with time-series discriminant component analysis.

    Science.gov (United States)

    Hayashi, Hideaki; Shima, Keisuke; Shibanoki, Taro; Kurita, Yuichi; Tsuji, Toshio

    2013-01-01

    This paper outlines a probabilistic neural network developed on the basis of time-series discriminant component analysis (TSDCA) that can be used to classify high-dimensional time-series patterns. TSDCA involves the compression of high-dimensional time series into a lower-dimensional space using a set of orthogonal transformations and the calculation of posterior probabilities based on a continuous-density hidden Markov model that incorporates a Gaussian mixture model expressed in the reduced-dimensional space. The analysis can be incorporated into a neural network so that parameters can be obtained appropriately as network coefficients according to backpropagation-through-time-based training algorithm. The network is considered to enable high-accuracy classification of high-dimensional time-series patterns and to reduce the computation time taken for network training. In the experiments conducted during the study, the validity of the proposed network was demonstrated for EEG signals.

  17. Engineering PQS biosynthesis pathway for enhancement of bioelectricity production in Pseudomonas aeruginosa microbial fuel cells

    DEFF Research Database (Denmark)

    Wang, Victor Bochuan; Chua, Song-Lin; Cao, Bin;

    2013-01-01

    cells with an approximate five-fold increase of maximum current density relative to the parent strain. Electrochemical analysis showed that the current increase correlates with an over-synthesis of phenazines. These results therefore demonstrate that targeting microbial cell-to-cell communication....... aeruginosa strain that produces higher concentrations of phenazines under anaerobic conditions by over-expressing the PqsE effector in a PQS negative ΔpqsC mutant. The engineered strain exhibited an improved electrical performance in microbial fuel cells (MFCs) and potentiostat-controlled electrochemical...

  18. The use of bioelectrical impedance analysis for body composition in epidemiological studies

    DEFF Research Database (Denmark)

    Böhm, A; Heitmann, B L

    2013-01-01

    with increased risk of developing chronic diseases. Studies, among others using BIA, suggest that low BMI may reflect low muscle and high BMI fat mass (FM). BIA-derived lean and FM is directly associated with morbidity and mortality. To the contrary, BMI is rather of limited use for measuring BF...

  19. A stable synergistic microbial consortium for simultaneous azo dye removal and bioelectricity generation.

    Science.gov (United States)

    Wang, Victor Bochuan; Chua, Song-Lin; Cai, Zhao; Sivakumar, Krishnakumar; Zhang, Qichun; Kjelleberg, Staffan; Cao, Bin; Loo, Say Chye Joachim; Yang, Liang

    2014-03-01

    Microbial species coexist in natural or engineered settings, where they encounter extensive competition and cooperation. Interactions occurring through metabolite exchange or direct contact might be important in establishment of functional biodegradation consortium. Understanding these interactions can facilitate manipulation of selected communities and exploitation of their capacity for specific industrial applications. Here, a simple dual-species consortium (Pseudomonas putida and Shewanella oneidensis) was established for examining simultaneous Congo red bioremediation in planktonic culture and power generation in anode biofilms. Compared to mono-species cultures, co-cultures generated higher current densities and could concurrently degrade Congo red over 72h. Disabling the large secreted adhesion protein, LapA, of P. putida greatly enhanced S. oneidensis biofilm formation on the anode, which increased power generation in co-cultures. This demonstrates simultaneous control of specific planktonic and biofilm communities could be effective in manipulating microbial communities for targeted applications.

  20. Development of three-dimension microelectrode array for bioelectric measurement using the liquidmetal-micromolding technique

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Ran, E-mail: liuran@tsinghua.edu.cn; Yang, Xueyao; Chen, Weixing [Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing 100084 (China); Jin, Cuiyun; Fu, Jingjing [College of Information Science and Technology, Beijing University of Chemical Technology, Beijing 100029 (China); Liu, Jing [Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing 100084 (China); Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100190 (China)

    2013-11-04

    A method of manufacturing three-dimension microneedle electrode arrays is presented in this paper using the micromolding technology with liquid metal at room temperature, based on the physical property of the Bi-In-Sn liquid metal alloy, being its melting point especially low. Observed under scanning electron microscopy, the needle body of the electrode chip manufactured using this method has a good consistency. Skin penetration test in-vitro indicates that the microneedle electrode can pierce the stratum corneum and cross the high-impedance layer to acquire electrical signals. Electrical impedance and polarization voltage experimental results show that the electrode chips have great electric characteristics and meet the practical application demands.

  1. Development of three-dimension microelectrode array for bioelectric measurement using the liquidmetal-micromolding technique

    Science.gov (United States)

    Liu, Ran; Yang, Xueyao; Jin, Cuiyun; Fu, Jingjing; Chen, Weixing; Liu, Jing

    2013-11-01

    A method of manufacturing three-dimension microneedle electrode arrays is presented in this paper using the micromolding technology with liquid metal at room temperature, based on the physical property of the Bi-In-Sn liquid metal alloy, being its melting point especially low. Observed under scanning electron microscopy, the needle body of the electrode chip manufactured using this method has a good consistency. Skin penetration test in-vitro indicates that the microneedle electrode can pierce the stratum corneum and cross the high-impedance layer to acquire electrical signals. Electrical impedance and polarization voltage experimental results show that the electrode chips have great electric characteristics and meet the practical application demands.

  2. Bioelectricity Generation in Mediator-Less Microbial Fuel Cell: Application of Pure and Mixed Cultures

    Directory of Open Access Journals (Sweden)

    S. Fatemi

    2012-01-01

    Full Text Available Microbial fuel cell (MFC is an emerging biotechnology which converts the organic substrates to electricity by electrogenic bacteria. In this study electricity generation was evaluated in a dual chambered mediator-less microbial fuel cell. Graphite plates were used as electrodes and glucose with initial concentration of 4 g.l-1 was used as electron donor. Anode chamber of the fabricated MFC was inoculated with two mixed cultures; anaerobic effluent of dairy manufacture (called A and anaerobic effluent of wastewater treatment plant (called B. Saccharomyces cerevisiae PTCC 5269 was used as pure culture. Power generation using these three inoculums was evaluated in the same condition including room temperature, without agitation and using glucose with initial concentration of 4 g.l-1 as substrate. The performance of MFC was analyzed by the measurement of polarization curve. Maximum power and current densities of 30.99 mW.m-2 and 391.68 mA.m-2; 25.90 mW.m-2 and 320.7604 mA.m-2 were obtained when culture B and A were used as inoculums, respectively. Power and current densities were 10.0224 mW.m-2 and 253.2964 mA.m-2 when S. cerevisiae was used as pure culture in MFC. Therewith chemical oxygen demand (COD removal efficiencies of 54, 71 and 75 % were achieved when S. cerevisiae, mix cultures A and B were used as inoculums, respectively. The investigation was targeted for the capability of mediator-less microbial fuel cell as combined wastewater treatment and electricity production unit.

  3. Bioelectricity Generation in Mediator-less Microbial Fuel Cell: Application of Pure and Mixed Cultures

    Directory of Open Access Journals (Sweden)

    Sakine Fatemi

    2012-01-01

    Full Text Available Microbial fuel cell (MFC is an emerging biotechnology, which converts the organic substrates to electricity by electrogenic bacteria. In this study, electricity generation was evaluated in a dual chamber mediator-less microbial fuel cell. Graphite plates were used as electrodes and glucose with initial concentration of 4 g/L was used as electron donor. Anode chamber of the fabricated MFC was inoculated with two mixed cultures; anaerobic effluent of dairy manufacture (called A and anaerobic effluent of wastewater treatment plant (called B. Saccharomyces cerevisiae PTCC 5269 was used as pure culture. Power generation using these three inoculums was evaluated in the same condition including room temperature, without agitation and using glucose with initial concentration of 4 g/L as substrate. The performance of MFC was analyzed by the measurement of polarization curve. Maximum power and current densities of 30.99 mW/m2 and 391.68 mA/m2; 25.90 mW/m2 and 320.7604 mA/m2 were obtained when culture B and A were used as inoculums, respectively. Power and current densities were 10.0224 mW/m2 and 253.2964 mA/m2 when S. cerevisiae was used as pure culture in MFC. Therewith, chemical oxygen demand (COD removal efficiencies of 54, 71 and 75% were achieved when S. cerevisiae, mix cultures A and B were used as inoculums, respectively. The investigation was targeted for the capability of mediator-less microbial fuel cell as combined wastewater treatment and electricity production unit.

  4. Bioelectrical Signal Processing in Cardiology: inverse solution mapping on epicardial and endocardial potentials

    OpenAIRE

    Ratés i Borràs, Àngels

    2015-01-01

    Inverse electrocardiography is aimed at reconstructing the heart electrical activity and its corresponding spread throughout the heart from non-invasive body surface measurements obtained through the Electrocardiogram (ECG) technique. This field has showed increasing promise during the last decades due to its main application: predict possible cardiac diseases such that medical interventions are avoided and costs which were meant to these clinical operations are also reduced. Still, properly ...

  5. Spatial dynamics of bioelectrical processes of brain during prolonged contact with physical factors

    Energy Technology Data Exchange (ETDEWEB)

    Suvorov, N.B.; Kukhtina, G.V.

    Study of the spatial organization of the EEG activity of the brain of man under normal circumstances and under prolonged effect of superhigh frequency electromagnetic fields involved examination of 155 workers ranging in age from 20 up to 39 years and working while exposed to electromagnetic fields for periods ranging from 2 up to 20 years and selection, from these, of 34 persons with no cerebral-cranial trauma, neuroinfection, psychotrauma, somatic or other diseases in their anamnesis for neurophysiological study. Monopolar EEG and EKG were registered during work and at psychosensory rest. Plasticity of the subjects' neurodynamic processes was assessed during voluntary regulation of the alpha-rhythm. Graphs of spatial-discrete interaction of isoelectric states of the EEG of the various zones of the brain were recorded by a digital computer. Prolonged periods of work while exposed to superhigh frequency electromagnetic fields produces phase changes of the spatial-discrete organization of neurorhythms of the brain. Working under these conditions for periods from 7 up to 14 years produces stress on the adaptational potentials of the organism and causes asthenization of mechanisms of self-regulation of the brain, which disturbs other functions of the organism. The maximum permissible period of work under these conditions is 7-14 years. 22 references, 4 figures.

  6. Bioelectrical impedance spectroscopy as a fluid management system in heart failure

    International Nuclear Information System (INIS)

    Episodes of hospitalization for heart failure patients are frequent and are often accompanied by fluid accumulations. The change of the body impedance, measured by bioimpendace spectroscopy, is an indicator of the water content. The hypothesis was that it is possible to detect edema from the impedance data. First, a finite integration technique was applied to test the feasibility and allowed a theoretical analysis of current flows through the body. Based on the results of the simulations, a clinical study was designed and conducted. The segmental impedances of 25 patients suffering from heart failure were monitored over their recompensation process. The mean age of the patients was 73.8 and their mean body mass index was 28.6. From these raw data the model parameters from the Cole model were deduced by an automatic fitting algorithm. These model data were used to classify the edema status of the patient. The baseline values of the regression lines of the extra- and intracellular resistance from the transthoracic measurement and the baseline value of the regression line of the extracellular resistance from the foot-to-foot measurement were identified as important parameters for the detection of peripheral edema. The rate of change of the imaginary impedance at the characteristic frequency and the mean intracellular resistance from the foot-to-foot measurement were identified as important parameters for the detection of pulmonary edema. To classify the data, two decision trees were considered: One should detect pulmonary edema (npulmonary = 13, nnone = 12) and the other peripheral edema (nperipheral = 12, nnone = 13). Peripheral edema could be detected with a sensitivity of 100% and a specificity of 90%. The detection of pulmonary edema showed a sensitivity of 92.31% and a specificity of 100%. The leave-one-out cross-validation-error for the peripheral edema detection was 12% and 8% for the detection of pulmonary edema. This enables the application of BIS as an early warning system for cardiac decompensation with the potential to optimize patient care. (paper)

  7. ACETONE REMOVAL AND BIOELECTRICITY GENERATION IN DUAL CHAMBER MICROBIAL FUEL CELL

    OpenAIRE

    Mostafa Rahimnejad; Mostafa Ghasemi; Ghasem Najafpour; Ali Ghoreyshi; Gholamreza Bakeri; Seyed Karim Hassani Nejad; Farid Talebnia

    2012-01-01

    Synthetic waste water contain organic compound can be oxidized in an anaerobic conditions in microbial fuel cell while biodegradation of Chemical Oxygen Demand (COD) takes place under anaerobic condition in anode compartment. The microorganisms for biological treatment of the organic matter were obtained from a UASFB bioreactor. In the treatment of waste water, ones COD was removed the current and power was generated and record. Also polarization curve was obtained. In cathode compartment fer...

  8. Bioelectricity inhibits back diffusion from the anolyte into the desalinated stream in microbial desalination cells.

    Science.gov (United States)

    Ping, Qingyun; Porat, Oded; Dosoretz, Carlos G; He, Zhen

    2016-01-01

    Microbial desalination cells (MDCs) taking advantage of energy in wastewater to drive desalination represent a promising approach for energy-efficient desalination, but concerns arise whether contaminants in wastewater could enter the desalinated stream across ion exchange membranes. Such back diffusion of contaminants from the anolyte into the desalinated stream could be controlled by two mechanisms, Donnan effect and molecule transport. This study attempted to understand those mechanisms for inorganic and organic compounds in MDCs through two independently conducted experiments. Donnan effect was found to be the dominant mechanism under the condition without current generation. Under open circuit condition, the MDC fed with 5 g L(-1) salt solution exhibited 1.9 ± 0.7%, 10.3 ± 1.3%, and 1.8 ± 1.2% back diffusion of acetic, phosphate, and sulfate ions, respectively. Current generation effectively suppressed Donnan effect from 68.2% to 7.2%, and then molecule transport became more responsible for back diffusion. A higher initial salt concentration (35 g L(-1)) and a shorter HRT (1.0 d) led to the highest concentration gradient, resulting in the most back diffusion of 7.1 ± 1.2% and 6.8 ± 3.1% of phosphate and sulfate ions, respectively. Three representative organic compounds were selected for test, and it was found that organic back diffusion was intensified with a higher salt concentration gradient and molecular weight played an important role in compound movement. Principal component analysis confirmed the negative correlation between Donnan effect and current, and the positive correlation between molecule transport and concentration gradient related conditions. PMID:26512804

  9. Conversion of Wastes into Bioelectricity and Chemicals by Using Microbial Electrochemical Technologies

    KAUST Repository

    Logan, B. E.

    2012-08-09

    Waste biomass is a cheap and relatively abundant source of electrons for microbes capable of producing electrical current outside the cell. Rapidly developing microbial electrochemical technologies, such as microbial fuel cells, are part of a diverse platform of future sustainable energy and chemical production technologies. We review the key advances that will enable the use of exoelectrogenic microorganisms to generate biofuels, hydrogen gas, methane, and other valuable inorganic and organic chemicals. Moreover, we examine the key challenges for implementing these systems and compare them to similar renewable energy technologies. Although commercial development is already underway in several different applications, ranging from wastewater treatment to industrial chemical production, further research is needed regarding efficiency, scalability, system lifetimes, and reliability.

  10. Bioelectrical impedance analysis (BIA) for sarcopenic obesity (SO) diagnosis in young female subjects

    Science.gov (United States)

    González-Correa, C. H.; Caicedo-Eraso, J. C.; S, Villada-Gomez J.

    2013-04-01

    Sarcopenia is defined as a loss of muscle mass depending of ageing and affecting physical function (definition A). A new definition considers excluding mass reduction criterion (definition B). Obesity is pandemic and occurs at all ages. Sarcopenic obesity (SO) implies both processes. The purpose of this study was to compare the results obtained after applying these 2 definitions in 66 aged 22 ± 2.8 years overweight or obese young college women. Percentage body fat (%BF) and skeletal mass index (SMI) were estimated by BIA, muscle function by handgrip strength test (HGS) and physical performance by Harvard step test (HST). There were 9.1% and 90.9% overweight or obese subjects. Twenty nine subjects (43.9%) had decreased HGS and 22 (33.3%) had impaired physical performance. One obese subject (1.5%) met the criteria for sarcopenic obesity by definition A and 9 (13.6%) by definition B. Although a linear regression (α obese, the problematic of SO will be found earlier in life.

  11. Pengembangan Bioelectrical Impedance Sebagai Control Commands Pengaturan Kecepatan Gerak Kursi Roda Dengan Metoda PID Controller

    Directory of Open Access Journals (Sweden)

    Juli Sardi

    2014-09-01

    Full Text Available In the present study, bioimpedance signals of human body was utilized to control speed of a wheelchair movement. A bioimpedance is electrically passive part contained the body tissues. The research is one of alternative solutions for patients with paralysis of the upper and lower limb. Firstly, design of system of the research consisted of bioimpedance measuring instruments and a mechanical design of the wheelchair. Bioimpedance measurement was performed by injecting a sinusoidal current source of 0.5 mArms with a frequency of 50 kHz to muscle tissue (shoulder to obtain the output voltage in the range of 0-5 Vdc. With impulse and manual thresholding methods, the voltage signal was classified into several controls command to adjust the speed and direction of the wheelchair control based on PID Controller. The experimental result of the research was realization of bioimpedance signal that used as a reference to control the direction and speed of the wheelchair with a success rate of 86.7 %. A wheelchair velocity was classified into three types of motion, namely slow, medium and fast. Slow speed has a rated speed of 30 Cm/s, medium speed value speed of 40 Cm/s and fast speed value of 50 Cm/s. The wheelchair can also turn to the left and the right in accordance with the wishes of wheelchair user beside to moving forward.

  12. ACETONE REMOVAL AND BIOELECTRICITY GENERATION IN DUAL CHAMBER MICROBIAL FUEL CELL

    Directory of Open Access Journals (Sweden)

    Mostafa Rahimnejad

    2012-01-01

    Full Text Available Synthetic waste water contain organic compound can be oxidized in an anaerobic conditions in microbial fuel cell while biodegradation of Chemical Oxygen Demand (COD takes place under anaerobic condition in anode compartment. The microorganisms for biological treatment of the organic matter were obtained from a UASFB bioreactor. In the treatment of waste water, ones COD was removed the current and power was generated and record. Also polarization curve was obtained. In cathode compartment ferocynide and potassium permanganate with several concentration were add for enhancement of proton oxidation. The performance of MFC for maximum current and power generation were obtained with 300 µM L-1 potassium permanganate as oxidizers agent. Maximum generated power and current densities were 22 mW/m2 and 70 mA/m2, respectively. Active microorganisms used acetone as electron donors and COD removal was 69% at the end of process.

  13. Location of Bioelectricity Plants in the Madrid Community Based on Triticale Crop: A Multicriteria Methodology

    Directory of Open Access Journals (Sweden)

    L. Romero

    2015-01-01

    Full Text Available This paper presents a work whose objective is, first, to quantify the potential of the triticale biomass existing in each of the agricultural regions in the Madrid Community through a crop simulation model based on regression techniques and multiple correlation. Second, a methodology for defining which area has the best conditions for the installation of electricity plants from biomass has been described and applied. The study used a methodology based on compromise programming in a discrete multicriteria decision method (MDM context. To make a ranking, the following criteria were taken into account: biomass potential, electric power infrastructure, road networks, protected spaces, and urban nuclei surfaces. The results indicate that, in the case of the Madrid Community, the Campiña region is the most suitable for setting up plants powered by biomass. A minimum of 17,339.9 tons of triticale will be needed to satisfy the requirements of a 2.2 MW power plant. The minimum range of action for obtaining the biomass necessary in Campiña region would be 6.6 km around the municipality of Algete, based on Geographic Information Systems. The total biomass which could be made available in considering this range in this region would be 18,430.68 t.

  14. Body Composition of Bangladeshi Children: Comparison and Development of Leg-to-Leg Bioelectrical Impedance Equation

    OpenAIRE

    Khan, I. (Imran); Hawkesworth, Ashraful; Hawlader, Sophie Mohammad Delwer Hossain; Arifeen, Shams El; Moore, Sophie; Hills, Andrew P; Wells, Jonathan C.; Persson, Lars-Åke; Kabir, Iqbal

    2012-01-01

    The aim of this study was to investigate the validity of the Tanita TBF 300A leg-to-leg bioimpedance analyzer for estimating fat-free mass (FFM) in Bangladeshi children aged 4-10 years and to develop novel prediction equations for use in this population, using deuterium dilution as the reference method. Two hundred Bangladeshi children were enrolled. The isotope dilution technique with deuterium oxide was used for estimation of total body water (TBW). FFM estimated by Tanita was compared with...

  15. Preliminary bioelectrical impedance analysis (BIA) equation for body composition assessment in young females from Colombia

    Science.gov (United States)

    Caicedo-Eraso, J. C.; González-Correa, C. H.; González-Correa, C. A.

    2013-04-01

    A previous study showed that reported BIA equations for body composition are not suitable for Colombian population. The purpose of this study was to develop and validate a preliminary BIA equation for body composition assessment in young females from Colombia, using hydrodensitometry as reference method. A sample of 30 young females was evaluated. Inclusion and exclusion criteria were defined to minimize the variability of BIA. Height, weight, BIA, residual lung volume (RV) and underwater weight (UWW) were measured. A preliminary BIA equation was developed (r2 = 0.72, SEE = 2.48 kg) by stepwise multiple regression with fat-free mass (FFM) as dependent variable and weight, height and impedance measurements as independent variables. The quality of regression was evaluated and a cross-validation against 50% of sample confirmed that results obtained with the preliminary BIA equation is interchangeable with results obtained with hydrodensitometry (r2 = 0.84, SEE = 2.62 kg). The preliminary BIA equation can be used for body composition assessment in young females from Colombia until a definitive equation is developed. The next step will be increasing the sample, including a second reference method, as deuterium oxide dilution (D2O), and using multi-frequency BIA (MF-BIA). It would also be desirable to develop equations for males and other ethnic groups in Colombia.

  16. Bioelectrical impedance spectroscopy to estimate fluid balance in critically ill patients.

    Science.gov (United States)

    Dewitte, Antoine; Carles, Pauline; Joannès-Boyau, Olivier; Fleureau, Catherine; Roze, Hadrien; Combe, Christian; Ouattara, Alexandre

    2016-04-01

    Fluid management is a crucial issue in intensive-care medicine. This study evaluated the feasibility and reproducibility of bioimpedance spectroscopy to measure body-water composition in critically ill patients, and compared fluid balance and daily changes in total body water (TBW) measured by bioimpedance. This observational study included 25 patients under mechanical ventilation. Fluid balance and bioimpedance measurements were recorded on 3 consecutive days. Whole-body bioimpedance spectroscopy was performed with exact or ideal body weights entered into the device, and with or without ICU monitoring. Reproducibility of bioimpedance spectroscopy was very good in all conditions despite ICU monitoring and mechanical ventilation. Bioimpedance measurements using an ideal body weight varied significantly, making the weighing procedure necessary. Comparison of fluid balance and daily changes in body weight provided the best correlation (ρ = 0.74; P 10 (ρ = 0.36; P = 0.05) and with extracorporeal circulation (ρ = 0.50; P = 0.005). Regardless of the technique used to estimate volume status, important limits of agreement were observed. Non-invasive determination of body-water composition using bioimpedance spectroscopy is feasible in critically ill patients but requires knowledge of the patient's weight. The best method to assess volume status after fluid resuscitation and the value gained from information about body composition provided by bioimpedance techniques needs further evaluation. PMID:26018457

  17. Relationship of percent body fat (estimated by bioelectrical impedance analysis with blood pressure among young adult females of Amritsar (Punjab

    Directory of Open Access Journals (Sweden)

    Bindiya Rana

    2012-10-01

    Full Text Available The present cross-sectional study was carried out to find the association of percent body fat (PBF with blood pressure (BP variables among apparently healthy young females studying in Guru Nanak Dev University, Amritsar. A total of 150 females ranging in age from 20-25 years were personally interviewed. Height and weight of each subject was taken using standard methodology. Their body composition parameters were taken by using body fat analyzer. Subjects were categorized as obese and non-obese according to PBF, in which those having >30% body fat was considered as obese. BP of each subject was measured by using the standard methodology. The prevalence of hypertension was calculated according to JNC VII criteria. In the pooled data, the percentage prevalence of obesity according to PBF was 36%. The percentage prevalence of pre-hypertension and hypertension in the pooled sample was 54% and 12%, respectively. However, it was observed that prevalence of hypertension was slightly more among obese females (7.3% as compared to non-obese (4.7% but the prevalence of pre-hypertension was significantly (p<0.05 more in non-obese females (39.3% as compared to obese females (14.7%. The underline cause of this high prevalence of pre-hypertension in non-obese subjects was not known. It is clear from the correlation analysis that no association was observed between SBP and MAP with PBF in obese and non-obese subjects while DBP is positively and significantly (p<0.05 correlated with weight, fat mass and fat free mass in non-obese subjects only. Thus it is concluded from this study that PBF measured by BIA was not likely to be a good predictor of high BP. Therefore, further large prospective studies on the association of hypertension and whole body fat and abdominal fat should be carried out to confirm the role of fat on BP.

  18. Endogenous bioelectric ifelds:a putative regulator of wound repair and regeneration in the central nervous system

    Institute of Scientific and Technical Information of China (English)

    Matthew L.Baer; Raymond J.Colello

    2016-01-01

    Studies on a variety of highly regenerative tissues, including the central nervous system (CNS) in non-mammalian vertebrates, have consistently demonstrated that tissue damage induces the formation of an ionic current at the site of injury. These injury currents generate electric ifelds (EF) that are 100-fold increased in intensity over that measured for uninjured tissue.In vitro and in vivo experiments have con-vincingly demonstrated that these electric ifelds (by their orientation, intensity and duration) can drive the migration, proliferation and differentiation of a host of cell types. These cellular behaviors are all necessary to facilitate regeneration as blocking these EFs at the site of injury inhibits tissue repair while enhancing their intensity promotes repair. Consequently, injury-induced currents, and the EFs they produce, represent a potent and crucial signal to drive tissue regeneration and repair. In this review, we will discuss how injury currents are generated, how cells detect these currents and what cellular responses they can induce. Addi-tionally, we will describe the growing evidence suggesting that EFs play a key role in regulating the cellular response to injury and may be a therapeutic target for inducing regeneration in the mammalian CNS.

  19. Biomagnetic and bioelectric detection of gastric slow wave activity in normal human subjects—a correlation study

    International Nuclear Information System (INIS)

    We measured gastric slow wave activity simultaneously with a Superconducting Quantum Interference Device (SQUID) magnetometer, mucosal electrodes and cutaneous electrodes in 18 normal human subjects (11 women and 7 men). We processed signals with Fourier spectral analysis and SOBI blind-source separation techniques. We observed a high waveform correlation between the mucosal electromyogram (EMG) and multichannel SQUID magnetogastrogram (MGG). There was a lower waveform correlation between the mucosal EMG and cutaneous electrogastrogram (EGG), but the correlation improved with the application of SOBI. There was also a high correlation between the frequency of the electrical activity recorded in the MGG and in mucosal electrodes (r = 0.97). We concluded that SQUID magnetometers noninvasively record gastric slow wave activity that is highly correlated with the activity recorded by invasive mucosal electrodes. (paper)

  20. Calibration of bioelectrical impedance analysis for body composition assessment in Ethiopian infants using air-displacement plethysmography

    DEFF Research Database (Denmark)

    Christensen, Rasmus Wibæk; Kæstel, Pernille; Skov, R.;

    2015-01-01

    , age and an impedance index (L(2)/Z50) were predictors. Prediction equations were developed using stepwise multiple linear regression and the accuracy was evaluated with a 10-fold cross-validation approach. RESULTS: A linear regression model based on body weight, age and sex predicted FFM, estimated...... model fit for predicting FFM compared with a model already comprising weight, sex and age. CONCLUSIONS: The derived equations predicted FFM with acceptable accuracy and may be used in future field surveys, epidemiological studies and clinical trials conducted in similar sub-Saharan African population...... groups aged 0-6 months.European Journal of Clinical Nutrition advance online publication, 1 April 2015; doi:10.1038/ejcn.2015.51....

  1. DXA, bioelectrical impedance, ultrasonography and biometry for the estimation of fat and lean mass in cats during weight loss

    Directory of Open Access Journals (Sweden)

    Borges Naida C

    2012-07-01

    Full Text Available Abstract Background Few equations have been developed in veterinary medicine compared to human medicine to predict body composition. The present study was done to evaluate the influence of weight loss on biometry (BIO, bioimpedance analysis (BIA and ultrasonography (US in cats, proposing equations to estimate fat (FM and lean (LM body mass, as compared to dual energy x-ray absorptiometry (DXA as the referenced method. For this were used 16 gonadectomized obese cats (8 males and 8 females in a weight loss program. DXA, BIO, BIA and US were performed in the obese state (T0; obese animals, after 10% of weight loss (T1 and after 20% of weight loss (T2. Stepwise regression was used to analyze the relationship between the dependent variables (FM, LM determined by DXA and the independent variables obtained by BIO, BIA and US. The better models chosen were evaluated by a simple regression analysis and means predicted vs. determined by DXA were compared to verify the accuracy of the equations. Results The independent variables determined by BIO, BIA and US that best correlated (p r2, 19 equations were selected (12 for FM, 7 for LM; however, only 7 equations accurately predicted FM and one LM of cats. Conclusions The equations with two variables are better to use because they are effective and will be an alternative method to estimate body composition in the clinical routine. For estimated lean mass the equations using body weight associated with biometrics measures can be proposed. For estimated fat mass the equations using body weight associated with bioimpedance analysis can be proposed.

  2. Feast or flee: bioelectrical regulation of feeding and predator evasion behaviors in the planktonic alveolate Favella sp. (Spirotrichia).

    Science.gov (United States)

    Echevarria, Michael L; Wolfe, Gordon V; Taylor, Alison R

    2016-02-01

    Alveolate (ciliates and dinoflagellates) grazers are integral components of the marine food web and must therefore be able to sense a range of mechanical and chemical signals produced by prey and predators, integrating them via signal transduction mechanisms to respond with effective prey capture and predator evasion behaviors. However, the sensory biology of alveolate grazers is poorly understood. Using novel techniques that combine electrophysiological measurements and high-speed videomicroscopy, we investigated the sensory biology of Favella sp., a model alveolate grazer, in the context of its trophic ecology. Favella sp. produced frequent rhythmic depolarizations (∼500 ms long) that caused backward swimming and are responsible for endogenous swimming patterns relevant to foraging. Contact of both prey cells and non-prey polystyrene microspheres at the cilia produced immediate mechanostimulated depolarizations (∼500 ms long) that caused backward swimming, and likely underlie aggregative swimming patterns of Favella sp. in response to patches of prey. Contact of particles at the peristomal cavity that were not suitable for ingestion resulted in depolarizations after a lag of ∼600 ms, allowing time for particles to be processed before rejection. Ingestion of preferred prey particles was accompanied by transient hyperpolarizations (∼1 s) that likely regulate this step of the feeding process. Predation attempts by the copepod Acartia tonsa elicited fast (∼20 ms) animal-like action potentials accompanied by rapid contraction of the cell to avoid predation. We have shown that the sensory mechanisms of Favella sp. are finely tuned to the type, location, and intensity of stimuli from prey and predators. PMID:26567352

  3. [Effect of refeeding on the body composition of females with restrictive anorexia nervosa; anthropometry versus bioelectrical impedance].

    Science.gov (United States)

    de Mateo Silleras, Beatriz; Redondo del Río, Paz; Camina Martín, Alicia; Soto Célix, María; Alonso Torre, Sara R; Miján de la Torre, Alberto

    2013-01-01

    Objetivo: Evaluar la composición corporal en un grupo de pacientes desnutridas con anorexia nerviosa, respecto de controles sanas, antes y después del soporte nutricional, mediante antropometría y bioimpedancia. Métodos: Estudio observacional prospectivo. Se realizó una antropometría completa y un análisis de bioimpedancia a 12 mujeres con anorexia nerviosa restrictiva (24,5 años) al ingreso hospitalario y semanalmente durante la realimentación. El grupo control estuvo formado por 24 mujeres sanas (21 años). Se aplicaron los test t-Student, U-Mann-Whitney, t-Student para medidas repetidas o Wilcoxon. La concordancia entre antropometría y BIA se analizó mediante el coeficiente de correlación intraclase y Bland-Altman. Resultados: Las pacientes mejoraron significativamente todos los índices de composición corporal a lo largo de la estancia hospitalaria, aunque sus valores al alta siguieron siendo menores que los de las controles. La media de peso ganado fue 5,22 kg (DE: 1,42), de los que el 51,4% fueron masa grasa, con distribución central preferentemente. En las controles la ecuación de BIA que mejor concuerda con antropometría es la de Sun (CCI = 0,896); en las pacientes la concordancia fue más débil, al ingreso y al alta. Conclusiones: La realimentación produce una ganancia ponderal, fundamentalmente a expensas de masa grasa, con distribución central; no se consigue restablecer el estado nutricional. La concordancia entre antropometría y bioimpedancia para el estudio de la composición corporal es aceptable, especialmente en sujetos sanos. Se recomienda emplear antropometría, si no se dispone de BIA vectorial o algún método gold estandard para el análisis de la composición corporal, en casos de alteraciones importantes en la composición corporal y/o el balance hídrico.

  4. Design and implementation of an impedance analyzer based on Arduino Uno : A pilot study of bioelectrical impedance analysis

    OpenAIRE

    Wang, Jing

    2015-01-01

    Electrical bioimpedance measurement is widely used today for monitoring body condition. The applications include and go beyond, body composition assessment, nutritional status evaluation, and cancer detection. The modalities for interpreting the impedance information have also developed quickly over the recent decades from single frequency bioimpedance analysis to spectrum and to images. Bioimpedance is measured by computing the relationship between voltage and current. In a current based bio...

  5. Efficient decolorization of real dye wastewater and bioelectricity generation using a novel single chamber biocathode-microbial fuel cell.

    Science.gov (United States)

    Kalathil, Shafeer; Lee, Jintae; Cho, Moo Hwan

    2012-09-01

    Large scale applications of microbial fuel cells (MFCs) have been severely hindered by several problems such as high internal resistance, low power output, expensive materials, and complicated configuration. To address these issues, a granular activated carbon based single chamber microbial fuel cell (GACB-SCMFC) has been designed using GAC-biocathodes without using any expensive materials for the simultaneous decolorization of real dye wastewater and electricity generation. The GACB-SCMFC produced a power density of 8 W/m(3) which indicates the GAC-biocathode can be a good alternative to platinum and other chemical catalysts. The dye wastewater was primarily treated at the anode and further polishing steps were occurred at the aerobic cathode. Toxicity measurement shows that the effluent after GACB-SCMFC operation was much less toxic compared to the original dye wastewater. Additional advantage of the GACB-SCMFC is that pH was automatically adjusted from 12.2 to 8 during 48 h of hydraulic retention time (HRT). PMID:22728177

  6. The Detection of Gastric Emptying with Bioelectrical Impedance%基于阻抗法的胃排空检测

    Institute of Scientific and Technical Information of China (English)

    王伟; 任超世; 李章勇; 魏进民

    2008-01-01

    胃排空功能是胃动力研究的主要内容之一,但临床缺乏经济、简单、易重复的检测方法.本文基于阻抗法进行胃排空检测研究,利用小波技术重构胃阻抗信号后快速获得了光滑的胃排空曲线,实现了半排空时间的准确计算.24例健康学生400ml纯净水的半排空时间为8.78±1.76min.

  7. On the magnetic field and the electrical potential generated by bioelectric sources in an anisotropic volume conductor

    NARCIS (Netherlands)

    Peters, M.J.; Elias, P.J.H.

    1988-01-01

    The electrical conductivity in biological tissue is often dependent on the direction of the fibres. In the paper the influence of this anisotropic nature on the electrical potential and magnetic field generated by a current dipole is studied analytically. Three different methods are discussed. The v

  8. Orthogonal Transformation in Bioelectrical Impedance Measurement%生物电阻抗测量中的正交变换

    Institute of Scientific and Technical Information of China (English)

    李镐炜; 董秀珍; 王跃科; 史学涛; 付峰

    2007-01-01

    探求生物电阻抗测量中,欧姆电阻和等效容抗间的数量关系.基于Cole-Cole阻抗模型,采用Cauchy积分公式进行了理论分析,并用多组实验数据对理论分析结果进行验证.验证实验结果在频率域的大部分范围内与理论分析结果一致.研究结果表明:生物电阻抗测量中,欧姆电阻和等效容抗之间存在确定的正交变换关系.

  9. Agreement between Omron 306 and Biospace InBody 720 Bioelectrical Impedance Analyzers (BIA) in Children and Adolescents

    Science.gov (United States)

    Finn, Kevin J.; Saint-Maurice, Pedro F.; Karsai, István; Ihász, Ferenc; Csányi, Tamás

    2015-01-01

    Purpose: The purpose of this study was to test the convergent validity of Omron 306 using Biospace InBody 720. Method: A total of 267 participants (145 boys; aged 10.4-17.9 years) completed testing during a single session. Each measure provided percent body fat (%BF), while the InBody 720 included fat-free mass (FFM). The validity was examined…

  10. Segmental Body Composition Assessment for Obese Japanese Adults by Single-Frequency Bioelectrical Impedance Analysis with 8-point Contact Electrodes

    OpenAIRE

    Sato, Susumu; Demura, Shinichi; Kitabayashi, Tamotsu; Noguchi, Takanori

    2007-01-01

    This study aimed to determine the accuracy of segmental body composition variables estimated by singlefrequency BIA with 8-point contact electrodes (SF-BIA8), compared with dual-energy X-ray absorptiometry (DXA). Subjects were 72 obese Japanese adults (43 males and 29 females) aged 30 to 66 years. Segmental body composition variables (fat free mass : FFM, fat mass : FM, and percent fat mass : %FAT) were measured by these techniques. The correlations between impedance values and FFM measured b...

  11. Bioelectrical impedance is an accurate method to assess body composition in obese but not severely obese adolescents.

    Science.gov (United States)

    Verney, Julien; Metz, Lore; Chaplais, Elodie; Cardenoux, Charlotte; Pereira, Bruno; Thivel, David

    2016-07-01

    The aim of this study was to compare total and segmental body composition results between bioimpedance analysis (BIA) and dual x-ray absorptiometry (DXA) scan and to test the reproducibility of BIA in obese adolescents. We hypothesized that BIA offers an accurate and reproducible method to assess body composition in adolescents with obesity. Whole-body and segmental body compositions were assessed by BIA (Tanita MC-780) and DXA (Hologic) among 138 (110 girls and 28 boys) obese adolescents (Tanner stage 3-5) aged 14±1.5years. The BIA analysis was replicated on 3 identical occasions in 32 participants to test the reproducibility of the methods. Whole-body fat mass percentage was significantly higher using the BIA method compared with DXA (40.6±7.8 vs 38.8±4.9%, PBioimpedance analysis offers an acceptable and reproducible alternative to assess body composition in obese adolescents, with however a loss of correlation between BIA and DXA with increasing body fat; its validity remains uncertain for segmental analysis among obese youth. PMID:27333957

  12. Application of bioelectrical impedance vector analysis (BIVA in dogs: a preliminary study on gender-related differences

    Directory of Open Access Journals (Sweden)

    Rebecca Ricci

    2010-01-01

    Full Text Available In this preliminary study, BIVA has been performed on 17 healthy Italian Hound dogs, 10 males (M and 7 females (F, in order to verify if gender-related differences can be detected. Only in F higher reactance (Xc values (F: 46.4 vs M: 37.7, P<0.05 and a significant negative correlation (-0.80, P<0.05 between BCS and resistance (R values were detected. 50%, 75% and 95% tolerance ellipses were calculated both in M and F using average Xc and R values standardized for withers height. Probably due to the low number of subjects used in the present study, the variability of the individual vector distribution (F: 79.6 vs M: 53.0Ohm/m, as well as the mean impedance vector lengtht (F: 548.2 vs M: 498.9Ohm/m, were similar in F and M. The gender-related difference in phase angle values was not significant (F: 0.168 vs M: 0.157, P=ns. In conclusion, the use of BIVA in dogs indicated differences between males and females which should be confirmed by a larger number of subjects.

  13. Bioelectricity generation in microbial fuel cell using natural microflora and isolated pure culture bacteria from anaerobic palm oil mill effluent sludge.

    Science.gov (United States)

    Nor, Muhamad Hanif Md; Mubarak, Mohd Fahmi Muhammad; Elmi, Hassan Sh Abdirahman; Ibrahim, Norahim; Wahab, Mohd Firdaus Abdul; Ibrahim, Zaharah

    2015-08-01

    A double-chambered membrane microbial fuel cell (MFC) was constructed to investigate the potential use of natural microflora anaerobic palm oil mill effluent (POME) sludge and pure culture bacteria isolated from anaerobic POME sludge as inoculum for electricity generation. Sterilized final discharge POME was used as the substrate with no addition of nutrients. MFC operation using natural microflora anaerobic POME sludge showed a maximum power density and current density of 85.11mW/m(2) and 91.12mA/m(2) respectively. Bacterial identification using 16S rRNA analysis of the pure culture isolated from the biofilm on the anode MFC was identified as Pseudomonas aeruginosa strain ZH1. The electricity generated in MFC using P. aeruginosa strain ZH1 showed maximum power density and current density of 451.26mW/m(2) and 654.90mA/m(2) respectively which were five times higher in power density and seven times higher in current density compared to that of MFC using anaerobic POME sludge.

  14. Change in fat-free mass assessed by bioelectrical impedance, total body potassium and dual energy X-ray absorptiometry during prolonged weight loss

    DEFF Research Database (Denmark)

    Hendel, H W; Gotfredsen, A; Højgaard, L;

    1996-01-01

    A total of 16 obese women (body mass index (BMI) 30-43 kg m(-2)) participated in a weight reduction study. Before and after a weight loss of 11.7 +/- 7.4 kg (mean +/- SD), body composition was assessed by dual energy X-ray absorptiometry (DXA), and total body potassium counting (TBK). These measu......A total of 16 obese women (body mass index (BMI) 30-43 kg m(-2)) participated in a weight reduction study. Before and after a weight loss of 11.7 +/- 7.4 kg (mean +/- SD), body composition was assessed by dual energy X-ray absorptiometry (DXA), and total body potassium counting (TBK...

  15. Change in fat-free mass assessed by bioelectrical impedance, total body potassium and dual energy X-ray absorptiometry during prolonged weight loss

    DEFF Research Database (Denmark)

    Hendel, H W; Gotfredsen, A; Højgaard, L;

    1996-01-01

    A total of 16 obese women (body mass index (BMI) 30-43 kg m(-2)) participated in a weight reduction study. Before and after a weight loss of 11.7 +/- 7.4 kg (mean +/- SD), body composition was assessed by dual energy X-ray absorptiometry (DXA), and total body potassium counting (TBK......). These measurements were compared with bioimpedance analysis (BIA) by applying 11 predictive BIA equations published in the literature. Predictive equations for the present study population were developed, with the use of fat-free mass (FFM) as assessed by TBK and DXA as references in multiple regression analysis...... equations are unable to predict static body composition and are not reproducible for individuals over time. However, a significant or insignificant change in R (without accompanying predictive equations) may be used to indicate whether FFM is lost or preserved in groups of obese subjects....

  16. A comparison between handgrip strength, upper limb fat free mass by segmental bioelectrical impedance analysis (SBIA) and anthropometric measurements in young males

    International Nuclear Information System (INIS)

    The mechanical function and size of a muscle may be closely linked. Handgrip strength (HGS) has been used as a predictor of functional performing. Anthropometric measurements have been made to estimate arm muscle area (AMA) and physical muscle mass volume of upper limb (ULMMV). Electrical volume estimation is possible by segmental BIA measurements of fat free mass (SBIA-FFM), mainly muscle-mass. Relationship among these variables is not well established. We aimed to determine if physical and electrical muscle mass estimations relate to each other and to what extent HGS is to be related to its size measured by both methods in normal or overweight young males. Regression analysis was used to determine association between these variables. Subjects showed a decreased HGS (65.5%), FFM, (85.5%) and AMA (74.5%). It was found an acceptable association between SBIA-FFM and AMA (r2 = 0.60) and poorer between physical and electrical volume (r2 = 0.55). However, a paired Student t-test and Bland and Altman plot showed that physical and electrical models were not interchangeable (pt2 = 0.07) and electrical (r2 = 0.192) ULMMV showing that muscle mass quantity does not mean muscle strength. Other factors influencing HGS like physical training or nutrition require more research.

  17. Electrochemical characteriztion of the bioanode during simultaneous azo dye decolorization and bioelectricity generation in an air-cathode single chambered microbial fuel cell

    International Nuclear Information System (INIS)

    To achieve high power output based on simultaneously azo dye decolorization using microbial fuel cell (MFC), the bioanode responses during decolorization of a representative azo dye, Congo red, were investigated in an air-cathode single chambered MFC using representative electrochemical techniques. It has been found that the maximum stable voltage output was delayed due to slowly developed anode potential during Congo red decolorization, indicating that the electrons recovered from co-substrate are preferentially transferred to Congo red rather than the bioanode of the MFC and Congo red decolorization is prior to electricity generation. Addition of Congo red had a negligible effect on the Ohmic resistance (Rohm) of the bioanode, but the charge-transfer resistance (Rc) and the diffusion resistance (Rd) were significantly influenced. The Rc and Rd firstly decreased then increased with increase of Congo red concentration, probably due to the fact that the Congo red and its decolorization products can act as electron shuttle for conveniently electrons transfer from bacteria to the anode at low concentration, but result in accelerated consumption of electrons at high concentration. Cyclic voltammetry results suggested that Congo red was a more favorable electron acceptor than the bioanode of the MFC. Congo red decolorization did not result in a noticeable decrease in peak catalytic current until Congo red concentration up to 900 mg l-1. Long-term decolorization of Congo red resulted in change in catalytic active site of anode biofilm.

  18. 一种改进的心脏电兴奋矢量传播算法%An Improved Vector Propagation Algorithm for Cardiac Bioelectric Excitation

    Institute of Scientific and Technical Information of China (English)

    陈强; 冯焕清; 彭虎

    2002-01-01

    矢量传播算法是一种新的心脏电兴奋传播算法,针对其缺陷,通过引入判断新波源的方法,提出了改进的矢量传播算法.仿真结果表明,该算法克服了原算法中不能准确计算介质中有阻碍情况下兴奋传播过程的局限性,同时保留了原算法精确快速的优点,有助于更准确地仿真某些病理波形.

  19. Parameter Optimization of Body Surface Laplacian Electrodes in Bioelectricity Detection%生物电检测中Laplacian电极的参数设计

    Institute of Scientific and Technical Information of China (English)

    何峰; 李刚; 林凌

    2007-01-01

    通过理论推导并结合工程实践,分析了Laplacian电极的各个参数对电极性能以及测量精度的影响,指出了一些设计中必须遵循的原则.并在此基础上,提出了一套基于误差分析和放大器噪声水平的参数评估标准.还特别指出,在工程计算中,取圆环电极的内径作为Laplacian电极的有效半径更有利于减小误差.同时,在被测信号过于微弱的情况下,可以适当增加电极的有效半径,以提高信噪比.

  20. Meridian resistance research based on bioelectricity amplifier%基于生物电放大器的经络阻抗研究

    Institute of Scientific and Technical Information of China (English)

    王学民; 常晓剑; 曹玉珍

    2007-01-01

    已有的经络定位方法都是定性或半定量的,而经络实质的研究需要一种定量的方法来实现经络的准确定位.将低频方波脉冲注入人体手掌的穴位,利用生物电放大器采集前臂一些部位的脉冲信号.根据经络的低阻抗特性,响应信号的大小与阻抗成反比.用Fourier变换和小波分析方法对采集到的实验数据进行分析处理,确定前臂响应信号的最大点,也即阻抗最小点,该点应在经络上.连接阻抗最小点,在前臂皮肤上可以形成一条线.研究表明,这种方法得到的连线与传统中医对经络的位置的描述一致.此研究结果为中医经络的研究提供了一种新的研究手段.

  1. Post-stroke and its bioelectrical treatment and Electrical Stimulation Cerebellar Fastigial Nucleus%脑卒中后抑郁及其生物电治疗

    Institute of Scientific and Technical Information of China (English)

    朱晓钢; 汤蕙; 王放; 杨平

    2004-01-01

    脑卒中后抑郁可影响脑卒中的治疗和预后.国际流行病学调查显示脑卒中后抑郁的总发生率为30%~40%,国内为34.2%左右.治疗脑卒中后抑郁可提高脑卒中治愈率,减少致残率,缩短住院时间,减轻社会和家庭的经济负担,使患者生活质量提高.根据脑卒中后抑郁的病因学研究,小脑生物电可刺激小脑顶核,使脑内传导通路激活,改善局部血流,抑制炎性反应,促进5-羟色胺生成,可减轻抑郁,恢复正常情绪,所以,小脑生物电治疗脑卒中后抑郁前景广泛.

  2. 生物电阻抗法人体腹部脂肪测量研究%Research on bioelectrical impedance measurement of abdominal fat

    Institute of Scientific and Technical Information of China (English)

    苌飞霸; 张和华; 尹军

    2015-01-01

    生物电阻抗提供了一种相对比较简便的测量人体成分的方法,具有无创、无害、廉价、操作简单和功能信息丰富的特点,而且测量结果准确、测量可重复性高等优点.文章阐述了目前测量人体成分的方法及生物电阻抗法人体成分测量研究模型;并阐述了生物电阻抗法对于人体腹部脂肪测量研究的难点;最后对未来生物电阻抗法人体成分测量系统发展进行了展望.所以对于传统的借助于生物电阻抗法测量人体成分系统具有重要的借鉴意义.

  3. 基于声电效应的生物电流源定位%Localization of Bioelectric Current Source Based on Acousto-electric Effect

    Institute of Scientific and Technical Information of China (English)

    张宁; 张鞠成; 徐文龙; 王志康; 徐冰俏; 卢向红

    2014-01-01

    生物电流源的实时准确定位对于房颤等电生理疾病的诊断具有重要意义.为了进行生物电流源的2维定位,基于声电效应和互易定理,采用有限元法仿真分析了2维导联场,再通过MATLAB对导联场数据进行处理,其中仿真模型选取质量分数为0.9%的NaCl溶液作为均匀导电介质.仿真结果表明,在均匀介质条件下,仅用l对探测电极即可实现生物电流源的精确定位,电流源和电流汇的仿真位置与实际位置之间的误差均≤0.04 mm.利用声电效应有望实现生物电流源的高精度实时定位,为房颤定位的临床实用化奠定了基础.

  4. Multi-frequency bioelectrical impedance: a comparison between the Cole-Cole modelling and Hanai equations with the classical impedance index approach.

    Science.gov (United States)

    Deurenberg, P; Andreoli, A; de Lorenzo, A

    1996-01-01

    Total body water and extracellular water were measured by deuterium oxide and bromide dilution respectively in 23 healthy males and 25 healthy females. In addition, total body impedance was measured at 17 frequencies, ranging from 1 kHz to 1350 kHz. Modelling programs were used to extrapolate impedance values to frequency zero (extracellular resistance) and frequency infinity (total body water resistance). Impedance indexes (height2/Zf) were computed at all 17 frequencies. The estimation errors of extracellular resistance and total body water resistance were 1% and 3%, respectively. Impedance and impedance index at low frequency were correlated with extracellular water, independent of the amount of total body water. Total body water showed the greatest correlation with impedance and impedance index at high frequencies. Extrapolated impedance values did not show a higher correlation compared to measured values. Prediction formulas from the literature applied to fixed frequencies showed the best mean and individual predictions for both extracellular water and total body water. It is concluded that, at least in healthy individuals with normal body water distribution, modelling impedance data has no advantage over impedance values measured at fixed frequencies, probably due to estimation errors in the modelled data.

  5. Bioelectrical impedance for detecting and monitoring lymphedema in patients with breast cancer. Preliminary results of the florence nightingale breast study group.

    Science.gov (United States)

    Erdogan Iyigun, Zeynep; Selamoglu, Derya; Alco, Gul; Pilancı, Kezban Nur; Ordu, Cetin; Agacayak, Filiz; Elbüken, Filiz; Bozdogan, Atilla; Ilgun, Serkan; Guler Uysal, Fusun; Ozmen, Vahit

    2015-03-01

    The aim of this study was to evaluate the efficacy of bioimpedance spectroscopy for the follow-up of patients with lymphedema in Turkey and its benefits in the diagnosis of stage 0, 1, and 2 lymphedema in patients who are under treatment for breast cancer. Thirty-seven female patients with breast cancer who underwent surgical procedures in our Breast Health Centre were followed up for lymphedema using bioimpedance, and clinical measurements were taken for a minimum period of 1 year at 3-month intervals. Patients who had been monitored regularly between November, 2011, and September, 2013, were enrolled to the study. In total, 8 patients developed lymphedema with an overall rate of 21.6%. Among the 8 patients who developed lymphedema, 4 had Stage 2, 1 had Stage 1, and 3 had Stage 0 lymphedema. Stage 0 lymphedema could not be detected with clinical measurements. During the patients' 1-year follow-up period using measurements of bioimpedance, a statistically significant relationship was observed between the occurrence of lymphedema and the disease characteristics. including the number of the extracted and remaining lymph nodes and the region of radiotherapy (p=0.042, p=0.024, p=0.040). Bioimpedance analysis seems to be a practical and reliable method for the early diagnosis of lymphedema. It is believed that regular monitoring of patients in the high-risk group using bioimpedance analyses increases the ability to treat lymphedema.

  6. A comparison between handgrip strength, upper limb fat free mass by segmental bioelectrical impedance analysis (SBIA) and anthropometric measurements in young males

    Science.gov (United States)

    Gonzalez-Correa, C. H.; Caicedo-Eraso, J. C.; Varon-Serna, D. R.

    2013-04-01

    The mechanical function and size of a muscle may be closely linked. Handgrip strength (HGS) has been used as a predictor of functional performing. Anthropometric measurements have been made to estimate arm muscle area (AMA) and physical muscle mass volume of upper limb (ULMMV). Electrical volume estimation is possible by segmental BIA measurements of fat free mass (SBIA-FFM), mainly muscle-mass. Relationship among these variables is not well established. We aimed to determine if physical and electrical muscle mass estimations relate to each other and to what extent HGS is to be related to its size measured by both methods in normal or overweight young males. Regression analysis was used to determine association between these variables. Subjects showed a decreased HGS (65.5%), FFM, (85.5%) and AMA (74.5%). It was found an acceptable association between SBIA-FFM and AMA (r2 = 0.60) and poorer between physical and electrical volume (r2 = 0.55). However, a paired Student t-test and Bland and Altman plot showed that physical and electrical models were not interchangeable (pt<0.0001). HGS showed a very weak association with anthropometric (r2 = 0.07) and electrical (r2 = 0.192) ULMMV showing that muscle mass quantity does not mean muscle strength. Other factors influencing HGS like physical training or nutrition require more research.

  7. Research of CMOS Integrated Biosensor for Extracellular Bioelectrical Signal Recording%用于细胞外电信号测量的CMOS集成生物传感芯片的研究

    Institute of Scientific and Technical Information of China (English)

    朱婷; 朱大中

    2006-01-01

    新型的细胞外电信号传感芯片是采用0.6 μm标准CMOS工艺设计制造,片上集成了6×6单元有源传感阵列、模拟多路选择器、输出缓冲器、参考源和数字控制电路.有源传感单元面积为60μm×60μm,包含15μm×15μm的传感电极和预处理电路,能够线性放大幅值范围100μV~25 mV的微小信号,电压增益为40dB.并采用相关二次采样工作模式降低固定模式噪声,提高传感器的精度.在标准CMOS工艺基础上,应用无电浸镀金改进传感电极的生物兼容性,并采用特殊封装技术提高芯片在溶液环境中的稳定性.溶液中模拟生物信号测量验证了该芯片的功能.%A new CMOS (complementary metal oxide silicon) biosensor chip designed for recording electrophysiological activities of in-vitro cultured cells is reported. It is designed and fabricated in a standard 0.6μm CMOS process, consisting of 6×6 active sensor array, analog multiplexer, output buffers, reference sources and digital controlling circuit. Each sensor cell is 60μm× 60μm in the dimension, including a 15μm×15μm electrode and a pre-processing circuit which could linearly amplify signals with peak-to-peak values from 100μV to 25 mV. The correlated double sampling circuit is utilized to remove the common-mode noise. Post-CMOS processes including electroless gold plating and special package technique are implemented to enhance the biocompatibility and stability of the biosensor. The tests carried out in the solution have verified the electrical functionality of the biosensor chip.

  8. Bioelectric and Morphological Response of Liquid-Covered Human Airway Epithelial Calu-3 Cell Monolayer to Periodic Deposition of Colloidal 3-Mercaptopropionic-Acid Coated CdSe-CdS/ZnS Core-Multishell Quantum Dots.

    Directory of Open Access Journals (Sweden)

    Aizat Turdalieva

    Full Text Available Lung epithelial cells are extensively exposed to nanoparticles present in the modern urban environment. Nanoparticles, including colloidal quantum dots (QDs, are also considered to be potentially useful carriers for the delivery of drugs into the body. It is therefore important to understand the ways of distribution and the effects of the various types of nanoparticles in the lung epithelium. We use a model system of liquid-covered human airway epithelial Calu-3 cell cultures to study the immediate and long-term effects of repeated deposition of colloidal 3-mercaptopropionic-acid coated CdSe-CdS/ZnS core-multishell QDs on the lung epithelial cell surface. By live confocal microscope imaging and by QD fluorescence measurements we show that the QD permeation through the mature epithelial monolayers is very limited. At the time of QD deposition, the transepithelial electrical resistance (TEER of the epithelial monolayers transiently decreased, with the decrement being proportional to the QD dose. Repeated QD deposition, once every six days for two months, lead to accumulation of only small amounts of the QDs in the cell monolayer. However, it did not induce any noticeable changes in the long-term TEER and the molecular morphology of the cells. The colloidal 3-mercaptopropionic-acid coated CdSe-CdS/ZnS core-multishell QDs could therefore be potentially used for the delivery of drugs intended for the surface of the lung epithelia during limited treatment periods.

  9. A study of promoting regeneration of peripheral nerve with simulated bioelectrical impulse of phrenic nerve%模拟膈神经脉冲电刺激促进周围神经再生的研究

    Institute of Scientific and Technical Information of China (English)

    夏奕俊; 徐向阳; 崔茂龙; 王成

    2004-01-01

    目的研究膈神经生物电脉冲(BIPN)对周围神经再生的促进作用.方法新西兰家兔18只平均分为3组,切断双侧坐骨神经后端端缝合予以电刺激.A组以BIPN刺激与无刺激对照;B组以BIPN刺激与方波脉冲刺激对照;C组以方波脉冲刺激与无刺激对照.刺激4周后行足底溃疡直径、神经电生理、胫前肌肌湿重、组织学和电镜超微结构检测.结果A、B组BIPN侧足底溃疡直径分别为(16.33±17.17) mm和(22.33±7.50) mm,均优于对照侧(P<0.01,P<0.05);复合肌肉诱发电位(CMAP)潜伏期分别为(1.98±0.20) ms和(1.92±0.16) ms,均优于对照侧(P<0.05);A组CMAP波幅为(0.18±0.07) mV,优于对照侧(P<0.05);远端有髓纤维通过率分别为(62.44±6.68)%和(54.48±5.05)%,均优于对照侧(P<0.01);胫前肌肌湿重分别为(1.67±0.24)g和(1.71±0.25)g,均优于对照侧(P<0.01);超微结构观察示BIPN侧再生髓鞘成熟度优于方波脉冲侧,更优于无刺激侧.结论膈神经电脉冲能较明显地促进周围神经再生.

  10. 一种基于生物电阻抗原理的人体成分测试装置的研制%The Development of a Body Composition Test Device based on Bioelectrical Impedance

    Institute of Scientific and Technical Information of China (English)

    祁朋祥; 马祖长; 孙怡宁; 刘世法

    2009-01-01

    人体内各种成分之间的合理比例是维持人体健康的重要因素.与同位素稀释法、总体钾法、双能X线吸收法(DXA)以及皮褶厚度法等方法相比,生物电阻抗法测量人体成分简单、快速和准确,是体成分测量的理想手段.我们介绍了基于生物电阻抗测量技术的体成分测量原理,并以此为指导设计了一种体成分测试仪.该仪器测试数据重复性高,与同类仪器的对比实验验证了其准确性.

  11. Novel methods for the measuement of bioelectric currents and the function imaging of tissue in body%生物电流检测和组织功能成像的新技术

    Institute of Scientific and Technical Information of China (English)

    刘军; 李光; 陈裕泉

    2003-01-01

    生物组织中主要是由于带电离子迁移而发生电活动,离子电流不但是肌肉收缩和神经冲动等生理活动的物理反映,而且也是所流经生物组织的电导率等电特性的反映.导体中的交变电流在正交磁场作用下受到Lorentz力而发生机械振动,进而产生声响应,反之,在外加磁场的情况下,导体中局部区域的机械振动产生相应的交变电流.根据这个原理,在外加磁场的情况下声场、电场相互正交耦合作用的生物电流检测和组织功能成像方法的提出为医学诊断提供了新的思路.本文介绍了相关的原理、实验和仪器的设计方案.

  12. 煤中硫被生物电化学协同脱出机理研究%Principium for revealing the desulfurization mechanism of coal by synergetic effect of microorganism and bioelectricity technology

    Institute of Scientific and Technical Information of China (English)

    巩冠群; 张英杰; 梅建; 马强; 尹苏东; 刘金艳; 陈巍; 许宁; 陶秀祥

    2007-01-01

    为了研究煤炭生物脱硫的机制,采用正交试验设计和生物、电化学、化学、物理等处理和分析方法,选取氧化亚铁硫杆菌驯化菌种对煤炭进行生物电化学脱硫研究.结果表明,生物电化学协同脱煤中硫氧化还原作用明显;氧化亚铁硫杆菌最高脱硫率可达76.2%,脱硫过程Fe2+浓度降低,Fe3+浓度缓慢上升,细菌表现生长周期规律;电化学调控生物脱硫提供了动力学规律和数据采集区间,细菌电化学脱硫微观机制为外电场循环激励、溶解氧、细菌催化、Fe3+的协同作用.

  13. Research on Constant-current Characteristics of Howland Current Source Used in Bioelectrical Impedance Detection%用于生物电阻抗检测的Howland电流源恒流特性研究

    Institute of Scientific and Technical Information of China (English)

    林兴建; 赵伟杰; 刘晓娟; 厉力华

    2015-01-01

    本研究旨在基于生物电阻抗检测应用,分析、改进Howland电流源电路,研究高输出阻抗和高稳定度的交变电流恒流源.从电阻匹配值、运放参数选择两个方面仿真研究Howland电流源的恒流特性,并对输出阻抗进行了分析.仿真实验结果表明Howland电流源在最佳匹配电阻值时有更好的恒流特性;运放参数影响Howland电流源恒流特性;在Howland电流源电路中,经过参数优化的电流源有较高的输出阻抗和带负载能力.研究提示Howland电流源在匹配电阻的选择上存在最佳匹配电阻值;高带宽、高压摆率和开环增益、宽范围供电电压的运算放大器更加适合于生物电阻抗检测电路.

  14. Digital surgery: Bioelectrical impedance measurement assistance on clinical operation%数字化外科:生物电阻抗测量技术辅助临床外科的操作

    Institute of Scientific and Technical Information of China (English)

    王智运; 尹庆水

    2011-01-01

    背景:现代临床外科操作对减少创伤和提高精确度的要求日益提高,生物电阻抗测量技术能将人体组织的信息转化为数字化信号,识别不同组织、器官,进而达到辅助临床操作的目的.目的:回顾分析生物电阻抗测量技术通过数字化转换辅助临床诊断、治疗以及手术等操作过程的情况.方法:由第一作者检索 1999/2009 PubMed数据及万方数据库有关使用生物电阻抗测量技术辅助临床诊断、治疗以及手术等操作,通过数字化信号的采集和分析达到实时定位、定性、提高精度和疗效评估等方面的文献.结果与结论:生物电阻抗测量技术以其无创、安全、可持续监控、多次测量和重复使用等优点,是一种理想的临床操作辅助手段.随着该技术新理论、新方法的不断发展,许多学者在此基础上对其辅助临床操作的应用进行了大量的研究和尝试,有理由相信其辅助应用的范围也将进一步扩大.%BACKGROUND: Modern chirurgery technique claims less trauma and higher precision. Bioelectical impedance measurement technique, which transfers anthropometric tissue information to digital signal, can afford aid to clinical surgery discriminate different tissue and organ.OBJECTIVE: To summarize the clinical application of bioelectical impedance measurement technique for assistance of the chirurgery operation.METHODS: Literatures about application of bioelectical impedance measu rement technique for the chirurgery operation were searched from Chinese Journal Full-text database and PubMed database, published from 1999 to 2009. Articles that qualitatively improve accuracy and curative effect evaluation using digital signal collection and analysis were analyzed.RESULTS AND CONCLUSION: The bioelectical impedance measurement technique is an ideal aided means, by the advantages of noninvasive, safe, durative monitoring, and repetitive use. With developing theory and methods of this technique, a large number of clinical trials have been conducted, which would enlarge its application.

  15. Development of the instrument for body component analysis——a realization of the bioelectrical impedance principle%人体成分分析仪设计——生物电阻抗原理的一种实现

    Institute of Scientific and Technical Information of China (English)

    撖涛; 孙怡宁; 姚志明

    2007-01-01

    生物电阻抗法测量人体成分是近20年发展起来的一项新技术.在比较了国内外同类仪器优缺点的基础上,研制了一种新型的人体成分分析仪,有效地解决了同类仪器中存在的不足.本文主要介绍了生物电阻抗原理和人体成分测试仪的软硬件实现.仪器采用八点接触电极法,实现了全自动多频检测和节段测量,通过CAN总线与监控设备互联,实现了一台电脑同时监测多台仪器,具有人体阻抗信号采集与显示,多种人体成分参数的计算等功能.此人体成分分析仪适合家庭医疗保健和医院保健科使用.

  16. 基于NI-cDAQ的生物电测量与治疗实验仪器的设计%Design of an Bioelectrical Measuring and Treating Instrument Based on NI-cDAQ

    Institute of Scientific and Technical Information of China (English)

    潘礼庆

    2010-01-01

    应用NI-CampactDAQ提供的一个高效、灵活、高速的通用测试平台,及选择合适的电路与芯片和设计独立的信号调理硬件模块,并对输入生物电信号进行隔离和放大,对输出激励信号进行隔离驱动,实现了仪器和输入、输出信号间的电气隔离.通过采用Labview虚拟仪器编程语言,可以快速地构建用于生物电测量与治疗的通用实验仪器.该仪器具有很强的扩展和数据处理功能,可安全用于人体测试,为医学院校开展生物电测量与治疗的实验教学提供安全、开放、功能强大的通用测试平台.

  17. Reliability of multifrequency segmental bioelectrical impedance analysis in measuring the character of human electricity%多频节段生物电阻抗分析法测量人体电学特征的信度研究

    Institute of Scientific and Technical Information of China (English)

    李雪迎; 于文; 王宁华

    2004-01-01

    目的:人体电阻抗特性是人体重要的物理特性之一,探讨多频节段生物电阻抗分析法测量人体节段电阻抗的可信度,对了解人体的健康状况,评价治疗效果都有重要的作用.方法:对43例受试者应用多频节段生物电阻抗分析法,在相同条件下对人体各节段电阻进行两次测量,两次测量之间间隔3 d,对测量结果进行统计分析.结果:除躯干节段对频率为5 kHz的交流电的阻抗值,其前后两次测量的相关系数偏低外,其他各项目测量所得的两次结果相关系数均>O.90.结论:应用多频节段生物电阻抗分析法测量人体成分具有较高的可重复性.

  18. EZ-USB FX2接口在生物电信号数据采集系统中的应用%Application of EZ-USB FX2 interface in bioelectrical data acquisition system

    Institute of Scientific and Technical Information of China (English)

    谢宏; 徐雪

    2009-01-01

    介绍EZ-USB FX2的结构和功能;给出基于EZ-USB FX2,FPGA控制A/D转换实现的生物电信号数据采集系统;重点说明了基于GPIF主控制方式的EZ-USB FX2接口设计及相应固件程序开发,并给出GPIF波形设计方案.

  19. 生物电阻抗技术建立运动人体特征性参数相关模型的价值%Application of bioelectrical impedance technique in constructing physiological parameters-related models of sports human

    Institute of Scientific and Technical Information of China (English)

    贺杰; 漆正堂

    2008-01-01

    生物电阻抗技术是利用生物组织与器官的电特性及其变化提取人体生物医学信息的一种无损伤检测技术.文章介绍了生物电阻抗技术的基本原理和研究方法,综述该技术的应用进展,分析其应用于运动人体科学的可行性.生物电阻抗技术在人体成分的测量、血液及血流动力学研究领域中的应用.可作为运动人体科学研究的借鉴;电阻抗断层图像技术为无创、实时、动态地监测运动人体器官与组织的结构和功能提供了可行性.可采取的研究策略是建立运动人体的特征性参数与生物电阻抗之间稳定町靠的相关模型或回归方程,运用统计学规律进行推断性研究.

  20. A signal analysis method for bioelectrical impedance measurement of gastric motility based on HHT%基于HHT的生物电阻抗胃动力信号分析方法

    Institute of Scientific and Technical Information of China (English)

    柴林燕; 赵舒; 沙洪

    2011-01-01

    Objective The Hilbert- Huang transformation (HHT) method was introduced to process the bio-impedance gastric motility signals from subjects.Methods Nonlinear and non-stationary original gastric motility series were decomposed into a number of intrinsic mode function (1MF) components by the empirical mode decomposition method (EMD).Hilbert transformation was carried out then and instantaneous frequency was extracted effectively.Gastric motility signal among 0.03-0.06 Hz was reconstructed from the IMF.Results The results suggested that HHT was a new and applicable time series analysis method based on mode decomposition and could extract impedance signal and remove the disturbances such as blood flow and breathing.Conclusion The new adaptive mode decomposition-based signal processing method provides a new method to investigate clinical gastric motility information.%目的 采用HHT时间序列分析方法处理从人体采集到的胃动力信号.方法 通过经验模态分解(EMD)技术将一非线性、非稳态过程的原始胃动力序列分解为一组内在模态函数(IMFs),对每一个IMF进行Hilbert 变换,得到信号的瞬时频率,然后选择与胃动力相关的频率成分,即0.03-0.06 Hz之间的IMF进行重构提取胃动力信号.结果 使用该方法可以有效去除叠加在阻抗胃动力信号中的呼吸和血流等干扰信号,保留胃动力信号的有效频率成分.结论 此方法是一种更具有自适应的、新型的、基于模态分解的时间序列数据处理方法,可以有效地为临床胃动力信息研究提供一种新途径.

  1. Energy balance, bioelectricity and emission of greenhouse gases from power plants in Mato Grosso do Sul; Balanco energetico, bioeletricidade e emissao de gases estufa das usinas de Mato Grosso do Sul

    Energy Technology Data Exchange (ETDEWEB)

    Turdera, Eduardo Mirko Valenzuela [Universidade Federal da Grande Dourados (UFGD), MS (Brazil)], email: eduardoturdera@ufgd.edu.br

    2010-07-01

    First we present in this paper the most important greenhouse gases emitted by sugar cane crops. The principal reference of the energy balance methodology and its theory are described. Furthermore, we show the yields of the unique energy balance applied to the sugar cane mills of Mato Grosso do Sul. The yields brings information about land use of the sugar cane crops, efficiency of technologies and process to produce ethanol and inputs about how the companies could improve its competitive position which involves, to care of environment impacts. Finally, we present the yield of CO{sub 2} emissions of the five mills evaluated. (author)

  2. Bioelectrical impedance and visceral fat: a comparison with computed tomography in adults and elderly; Bioimpedancia eletrica e gordura visceral: uma comparacao com a tomografia computadorizada em adultos e idosos

    Energy Technology Data Exchange (ETDEWEB)

    Eickemberg, Michaela [Universidade Federal da Bahia (UFBA), Salvador, BA (Brazil); Roriz, Anna Karla Carneiro [Universidade Federal da Bahia (UFBA), Salvador, BA (Brazil); Fontes, Gardenia Abreu Vieira [Universidade Federal da Bahia (UFBA), Salvador, BA (Brazil); Sampaio, Lilian Ramos [Universidade Federal de Sao Paulo (Unifesp), Sao Paulo, SP (Brazil)

    2013-05-01

    Objective: To evaluate the association between electrical bioimpedance analysis (BIA) and visceral fat (VF) in adult and elderly patients. Subjects and methods: This was a cross-sectional study, with a sample of 191 subjects (52% women, 49% elderly) stratified by sex, age and body mass. Computerized tomography (VF area) and BIA (percentage of total body fat (%TBF-BIA), phase angle, reactance and resistance) data were generated. Statistical analysis was based on Pearson's Correlation Coefficient, Anova, Pearson's Chi-square, and ROC curves. Results: VF areas {>=} 130 cm{sup 2} were more prevalent among the elderly and among men. Adult females showed a stronger correlation between GV and %TBF-BIA. The other groups showed similar results and statistically significant correlations. Correlations between GV and phase angle were weak and not statistically significant. ROC Curves analyzes showed the following %TBF-BIA, which identified excess VF: for male subjects: 21.5% (adults) and 24.25% (elderly); for female subjects: 35.05% (adults) and 38.45% (elderly) with sensitivity of 78.6%, 82.1%, 83.3%, and 66.7%, and specificity of 70.6%, 62.5%, 79.1%, and 69%, respectively. Conclusion: BIA was found to have satisfactory sensitivity and specificity to predict VF; however, other devices and other techniques should be investigated to improve VF prediction. (author)

  3. From Neural Plate to Cortical Arousal—A Neuronal Network Theory of Sleep Derived from in Vitro “Model” Systems for Primordial Patterns of Spontaneous Bioelectric Activity in the Vertebrate Central Nervous System

    Directory of Open Access Journals (Sweden)

    Michael A. Corner

    2013-05-01

    Full Text Available In the early 1960s intrinsically generated widespread neuronal discharges were discovered to be the basis for the earliest motor behavior throughout the animal kingdom. The pattern generating system is in fact programmed into the developing nervous system, in a regionally specific manner, already at the early neural plate stage. Such rhythmically modulated phasic bursts were next discovered to be a general feature of developing neural networks and, largely on the basis of experimental interventions in cultured neural tissues, to contribute significantly to their morpho-physiological maturation. In particular, the level of spontaneous synchronized bursting is homeostatically regulated, and has the effect of constraining the development of excessive network excitability. After birth or hatching, this “slow-wave” activity pattern becomes sporadically suppressed in favor of sensory oriented “waking” behaviors better adapted to dealing with environmental contingencies. It nevertheless reappears periodically as “sleep” at several species-specific points in the diurnal/nocturnal cycle. Although this “default” behavior pattern evolves with development, its essential features are preserved throughout the life cycle, and are based upon a few simple mechanisms which can be both experimentally demonstrated and simulated by computer modeling. In contrast, a late onto- and phylogenetic aspect of sleep, viz., the intermittent “paradoxical” activation of the forebrain so as to mimic waking activity, is much less well understood as regards its contribution to brain development. Some recent findings dealing with this question by means of cholinergically induced “aroused” firing patterns in developing neocortical cell cultures, followed by quantitative electrophysiological assays of immediate and longterm sequelae, will be discussed in connection with their putative implications for sleep ontogeny.

  4. 应用生物电阻抗法分析血液透析患者的人体组成%Use of Bioelectrical Impedance Analysis in Patients under Hemodialysis

    Institute of Scientific and Technical Information of China (English)

    马文君; 戚本华; 宁丽梅; 余薇

    2007-01-01

    目的 应用生物电阻抗法(BIA)检测血液透析(HD)患者身体组成的改变.方法 将122例HD稳定患者按体质指数(BMI)分为消瘦组(BMI<18.5)、正常组(BMI 18.5~23.9)和超重肥胖组(BMI≥24).采用单频体脂肪测量仪测量透析后患者的体重(WT) 、总体水(TBW)、脂肪组织(FM)和非脂肪组织(FFM),并与用Watson公式计算的TBW进行比较.同时计算尿素消除率(Kt/V).结果 (1)超重肥胖组人体组成各指标均明显高于正常组(P<0.005, P<0.001),消瘦组人体组成各指标均明显低于正常组(P均<0.001).(2)Watson公式计算的男、女TBW分别为34.4±4.2和26.9±2.7,明显低于BIA法的36.0±5.2(P<0.001)和27.7±3.8(P<0.05).(3)超重肥胖组Kt/V为1.3±0.2,明显低于正常组的1.5±0.2(P<0.001),Kt/V与BMI、TBW、FFM呈负相关(P<0.001).结论 不同BMI HD患者的人体组成变化明显,BIA对评估HD后体液平衡状态和营养状况有十分重要的意义.

  5. Research on the relationship between pregnancy and fetal birth weight by bioelectrical impedance analysis%母体生物电阻抗分析与新生儿出生体质量关系的研究

    Institute of Scientific and Technical Information of China (English)

    林锦芬; 吴元赭; 王新颖; 刘美燕

    2008-01-01

    目的:探讨孕期母体体质量增加及人体成分的改变与新生儿出生体质量间的关系.方法:选择来我院建保健卡的单胎健康孕妇70例,分别于孕中期(24~25周)和孕晚期(37~38周)测人体成分,同时监测同期胎儿生长发育状况.结果:共有63例孕妇完成所有的测量项目.孕中期和孕晚期的体质指数(BMI)、蛋白质、无机盐、肌肉量、脂肪量(FM)等与新生儿出生体质量间无相关性(P>0.05);孕中期和晚期的基础代谢率(BMR)、细胞内液(ICW),细胞外液(ECW),总体水(TBW),去脂体质(FFM),体细胞群(BCM)、上臂肌围(AMC)等与母亲体质量的增加有关,且与胎儿出生体质量呈显著相关(P<0.05).结论:孕期母体体质量的增加与母亲人体成分的组成和改变有关,并且能影响胎儿的生长发育及出生体质量,FFM是新生儿出生体质量的一个预测因素.

  6. Study on the formulas predicted for body fat of children and adolescence by using bioelectrical impedence analysis%中国7~18岁人群应用生物电阻抗法估算体脂方程

    Institute of Scientific and Technical Information of China (English)

    王京钟; 王筱桂; 胡小琪; 马冠生

    2008-01-01

    目的 建立生物电阻抗方法(BIA)测量中国儿童青少年体脂含量的应用方程.方法 按中各性别和年龄段超重的BMI参考值,将总人群分为体重正常组和超重肥胖组.以水下称重方法为标准方法,采用多元线性逐步回归方法,建立不同BMI水平7~18岁儿童青少年BIA的应用方程.结果 体重正常组方程:去脂体重(FFM,kg)=0.406weight+2.918sex+0.315H2/z+0.843;超重肥胖组方程:FFM(kg)=0.358weight+1.571sex+0.358H2/z+0.603;总人群方程:FFM(ks)=0.290weight+2222sex+0.427H2/z+1.547.三个方程的调整回归系数(r2)和标准误(SEE)分别为:0.940和2.36;0.955和2.46;0.942和2.53,方程的统计学检验均有显著性意义(ANOVA,P<0.001).结论 本研究建立的BIA应用方程与国内外同类研究相比,具有较高的可靠性.

  7. A comparison of dual energy x-ray absorptiometry and two bioelectrical impedance analyzers to measure body fat percentage and fat-free mass index in a group of Mexican young women.

    Science.gov (United States)

    Velazquez-Alva, Maria Del Consuelo; Irigoyen-Camacho, Maria Esther; Huerta-Huerta, Raquel; Delgadillo-Velazquez, Jaime

    2014-05-01

    Introducción: Los estudios de obesidad requieren estimación de masa grasa (FM) y masa libre de grasa (FFM). Objetivo: Comparar dos equipos de impedancia bioeléctrica (BIA) para estimar FM y FFM usando absorciometría de rayos X de energía dual (DXA) como referencia. Métodos: Estudio transversal. FM y FFM fueron evaluados por DXA y BIA: sistema pie-pie (FFS) y sistema mano-pie (HFS). Se realizaron pruebas t pareadas, coeficientes de correlación y análisis de Bland y Altman. Limites de acuerdo fueron calculados (CL). Resultados: Fueron estudiadas 175 mujeres (22,9 ± 2,2 años). Hubo diferencias significativas entre el promedio del porcentaje de grasa estimado por los equipos de BIA en comparación con DXA (FFS = 28,7%, HFS = 34,4% y DXA = 35,3%). La diferencia de medias del porcentaje de grasa entre HFS y DXA fue -0.96, (CL -5,29, 7,21). La diferencia de medias para FFS fue de -6,69,(CL -0,29, - 13.09) Hubo diferencias significativas entre las estimaciones de FFMI por BIA y DXA (FFS = 16,29, HFS = 14,95, DXA = 14,18). La diferencia de medias entre HFS y DXA fue = 0,78, (CL -2,27, 0,72) y la diferencia de medias de FFS fue -2,11: (CL -3,73 , -0,49). Conclusiones: Niveles diferentes de sesgo se observaron entre los equipos de BIA. El HFS parece ser más confiable que el FFS, sobre todo en la obtención de FFMI en mujeres jóvenes.

  8. Analysis of Body Composition Methods in a Community Sample of African American Women

    OpenAIRE

    Lopez, Ygnacio; O’Connor, Daniel P.; Ledoux, Tracey A.; Rebecca E. Lee

    2011-01-01

    The purposes of the authors in this study were: (1) to determine whether published body mass index and bioelectrical impedance analysis equations agreed with dual energy x-ray absorptiometry body fat percentage measures and (2) to estimate new body mass index and bioelectrical impedance analysis equations in a sample of African American women. Linear regression was used to determine how well 10 body mass index and bioelectrical impedance analysis equations reflected dual energy x-ray absorpti...

  9. Correlation between birth weight and maternal body composition.

    LENUS (Irish Health Repository)

    Kent, Etaoin

    2013-01-01

    To estimate which maternal body composition parameters measured using multifrequency segmental bioelectric impedance analysis in the first trimester of pregnancy are predictors of increased birth weight.

  10. Сhanges of eeg correlation dimension by trigeminal neuralgia

    Directory of Open Access Journals (Sweden)

    Vitaly P. Omelchenko

    2011-05-01

    Full Text Available This article focuses on the nonlinear analysis of brain bioelectric activity by trigeminal neuralgia. Paid attention to the comparison of patient’s and health people’s EEG correlation dimension.

  11. Investigation of the Surrounding Environment's Influence on Gait Sensing Using a Plant as a Sensor

    Directory of Open Access Journals (Sweden)

    Shigeki Hirobayashi

    2009-01-01

    In addition, we monitored the effect of a person walking on the spot near the plant on the bioelectric potential of the plant. Six subjects stepped on the spot 50 cm from a rubber tree and we measured the variation in the bioelectric potential of the tree produced by this stepping motion. The results confirmed that stepping motion produces a measurable response in the bioelectric potential of a plant and that this response varies in synchrony with the subject's stepping rate. Moreover, by conducting principal component analysis using the peak value of the spectrum characteristics of the measured bioelectric potential, cumulative proportion was found to reach nearly 97% at low-frequency components up to the fifth peak.

  12. Finite element simulations of magnetomyograms of rat skeletal muscle

    NARCIS (Netherlands)

    Rutten, W.L.C.; Wildeman, A.; Rozijn, T.H.

    1990-01-01

    The following topics are dealt with: biosensors; cardiology; processing of bioelectric signals; biomedical application of automatic control; lasers and electrooptics; computers in medicine; expert systems in medicine; fractals in biomedical engineering; neural networks; biophysical and biochemical m

  13. Medicinsk Elektronik

    DEFF Research Database (Denmark)

    Andersen, Ole Trier

    1998-01-01

    Lecture noter for the course in Medical Electronics covering the following topics: Nerve and muscle physiology; bioelectrical signal amplification and recording; blood pressure and flow measurements; cardiology; medical applications of ultrasound; medical imaging methods: CT, MR, SPECT, and PET...

  14. EEG CHARACTERISTICS AND THYROID PROFILE RATIO IN ADOLESCENTS OF SUBPOLAR AND POLAR EUROPEAN NORTH AREAS

    OpenAIRE

    D. B. Demin; L. V. Poskotinova; Ye. V. Krivonogova

    2013-01-01

    Features of brain bioelectric activity and thyroid system in adolescents living in Subpolar andPolar regionsof the North are considered. Hyperactivity of subcortical diencephalic brain structures in adolescents of the Polar region is revealed. Adolescents of Subpolar region have more intensive age optimization of neurodynamic processes. There are noted latitude distinctions of thyroid hormones role for age formation of brain bioelectric activity in adolescents.

  15. EEG CHARACTERISTICS AND THYROID PROFILE RATIO IN ADOLESCENTS OF SUBPOLAR AND POLAR EUROPEAN NORTH AREAS

    Directory of Open Access Journals (Sweden)

    D. B. Demin

    2013-01-01

    Full Text Available Features of brain bioelectric activity and thyroid system in adolescents living in Subpolar andPolar regionsof the North are considered. Hyperactivity of subcortical diencephalic brain structures in adolescents of the Polar region is revealed. Adolescents of Subpolar region have more intensive age optimization of neurodynamic processes. There are noted latitude distinctions of thyroid hormones role for age formation of brain bioelectric activity in adolescents.

  16. [Effects of transcranial magnetotherapy on electroencephalographic parameters in females with overactive urinary bladder].

    Science.gov (United States)

    Neĭmark, A I; Klyzhina, E A; Neĭmark, B A; Mel'nik, M A

    2007-01-01

    Urodynamic parameters and bioelectric brain activity were studied in 30 females aged 24-66 years with overactive bladder (OAB) before and after transcranial magnetotherapy. It was found that OAB patients have disorders of bioelectric brain activity by two types of EEG patterns (I.A. Svyatogor classification)--thalamic and stem, Patients with thalamic type EEG benefit more from magnetotherapy higher efficacy of which manifests with regress of clinical symptoms and urodynamic improvement. PMID:18254224

  17. Development of a capacitive bioimpedance measurement system

    OpenAIRE

    Gómez Abad, Daniel

    2009-01-01

    Bioelectrical impedance spectroscopy (BIS) is a well-established and non-invasive method to determine and monitor body composition. Commercially available bioelectrical impedance systems use coated hydrogel-aluminium electrodes, where the hydrogel acts as an adhesive and as an electrolytic medium. The gel/adhesive is physiologically inert over short periods. However, when used over longer periods, hydrogel-aluminium electrodes present limitations, which capacitive electrodes ma...

  18. Transmembrane voltage potential of somatic cells controls oncogene-mediated tumorigenesis at long-range

    OpenAIRE

    Chernet, Brook T.; Levin, Michael

    2014-01-01

    The microenvironment is increasingly recognized as a crucial aspect of cancer. In contrast and complement to the field's focus on biochemical factors and extracellular matrix, we characterize a novel aspect of host:tumor interaction – endogenous bioelectric signals among non-excitable somatic cells. Extending prior work focused on the bioelectric state of cancer cells themselves, we show for the first time that the resting potentials of distant cells are critical for oncogene-dependent tumori...

  19. Neural Engineering

    Science.gov (United States)

    He, Bin

    About the Series: Bioelectric Engineering presents state-of-the-art discussions on modern biomedical engineering with respect to applications of electrical engineering and information technology in biomedicine. This focus affirms Springer's commitment to publishing important reviews of the broadest interest to biomedical engineers, bioengineers, and their colleagues in affiliated disciplines. Recent volumes have covered modeling and imaging of bioelectric activity, neural engineering, biosignal processing, bionanotechnology, among other topics.

  20. BIOPOWERSWITCH. A Biomass Blueprint to Meet 15% of OECD Electricity Demand by 2020

    Energy Technology Data Exchange (ETDEWEB)

    Bauen, A.; Woods, J. [Centre for Energy Policy and Technology, Imperial College London, London (United Kingdom); Hailes, R. [E4tech, London (United Kingdom)

    2004-05-01

    This study evaluates the potential for sustainable power production from biomass and its contribution to the reduction of CO2 emissions in the medium term (2020), with a focus on OECD countries. In particular, the study: Reviews the current status of bioelectricity and its costs; Derives an indicative potential for biomass power by 2020; Discusses criteria and best practices for sustainable bioelectricity production; and Discusses policy measures for successful biomass energy development.

  1. イヌの肥満度判定における、BCS法とイヌ用体脂肪計による体脂肪率測定の比較

    OpenAIRE

    桜井, 富士朗; 松井, 桃子; 田畑, 憂香; 辻田, 夏希; 島田, 真美; Fujiro , SAKURAI; Momoko , Matsui; Yuka , Tabata; Natsuki , Tsuzita; Mami, Shimada; Ron動物病院; 帝京科学大学生命環境学部アニマルサイエンス学科; 有限会社サンラボ

    2011-01-01

    Body condition score (BCS) is assigned on the 5-point scale which is based on visual inspectiion of dogs. This is one of the most common methods in veterinary clinical. Body fat percentage is obtained by bioelectric device (BID) to evaluate bioelectric impedance of body composition. To estimate the relationship between the body condition score and the body fat percentage, physical examination records for nineteen healthy family dogs kept by TUS students were conducted. . With simple regressio...

  2. 空气置换法、生物电阻抗法与皮褶厚度法测试身体成分的比较研究%Comparative Study of Air Displacement Plethysmography, Bioelectrical Impedance Analysis and Skinfold Thickness in the Determination of Adult Body Fat Percentage

    Institute of Scientific and Technical Information of China (English)

    金晶; 庄洁; 陈佩杰; 王人卫

    2008-01-01

    目的:探讨生物电阻抗法与皮褶厚度法测定身体成分的结果与空气置换法(BOD-POD)结果的相关性.方法:随机选取20~59岁上海市居民697名(男471名,女226名),以空气置换法测定的身体成分值作为标准,将生物电阻抗法(OMRON与TANITA)和皮褶厚度法(测量部位为上臂部和肩胛部)的结果与之进行单因素方差分析和相关性分析.结果:皮褶厚度法测试结果与空气置换法结果相关性最低;生物电阻抗法中,TANITA测试结果与空气置换法结果相关性最高,OMRON相关性较低.结果提示:生物电阻抗法中TANI-TA测量的可靠性相对较高,皮褶厚度法(测量部位为上臂部和肩胛部)测量的可靠性相对较低.

  3. Realization of a New Segmental Bioelectrical Impedance Method for Assessing Body Composition: Correlation Analysis of Human Body Parameters%一种新的分段生物电阻抗评估人体成分方法的实现:人体参数相关性分析

    Institute of Scientific and Technical Information of China (English)

    肖贵遐; 刘国庆; 李湘荣; 郭云波; 吴建春

    2001-01-01

    用分段生物电阻抗方法评估人体成分需测量人体各段的长度或横截面积,增加了这种方法的复杂性.本文通过分析人体参数间相关性,得到了用性别、身高、体重表示的各段参数的线性回归等式,从而简化了分段阻抗法.

  4. 模拟高压输电线路电磁辐射对实验大鼠生物电参数影响的研究%Study on Effects of Bioelectric Parameters of Rats in Electromagnetic Radiation of HV Transmission Line

    Institute of Scientific and Technical Information of China (English)

    张安英; 庞小峰; 袁平

    2007-01-01

    随着经济的发展和信息时代的来临,各种频段的电磁波无处不在,人们日益暴露于其中.电磁辐射对人体健康的影响是多方面的,为了研究高压输电线路(High-voltage transmission line, HV transmission line)电磁辐射(Electromagnetic radiation, EM radiation)对大鼠脑电、心电和肌电等生物电参数的影响,测量了暴露在模拟高压输电线路电磁辐射环境下一年的大鼠脑电图,心电图和肌电图,并测量了其脑组织红外吸收谱,发现对照组和暴露组大鼠脑电各频段所占比例没有显著性差异,但是,二者脑组织的红外吸收谱存在显著差异;暴露组大鼠的心率、心动周期、P波时程、T波时程和T波高度与对照组相比都有不同程度的改变;暴露组大鼠的肌肉复合电位(Compound muscle action potential, CMAP)潜伏期与对照组相比没有显著差异,但其峰-峰值有显著差异.这些结果提示模拟高压输电线路电磁辐射对长期暴露在其中的大鼠神经电生理参数存在一定的影响.

  5. 人体刺激诱发生物电信号频率与占空比测量电路的设计与应用%Design and Application of a Circuit for Measuring Frequency & Duty Cycle of Stimulated Bioelectrical Signal

    Institute of Scientific and Technical Information of China (English)

    汤黎明; 常本康; 刘铁兵; 吴敏; 凌刚

    2002-01-01

    目的设计一种人体刺激诱发生物电信号频率和占空比测量电路,以解决在"神经阈值图谱与临床应用"研究项目中遇到的人体神经系统刺激诱发生物电信号频率与占空比测量的难题.方法首先根据人体神经系统刺激诱发生物电信号的频率较低并且极其不规则,以及频率和占空比变化非常频繁等特性,构思电路原理,然后进入实际设计、测试和改进,最终将其应用于精密神经阈值刺激仪中.结果电路经调试和改进,应用Agilent 33120A数字函数信号发生器和TDS3034B数字存贮示波器对多种波型、多种频率和占空比的信号进行测量,测量电路对各种信号频率的测量是相当准确的,对占空比的测量误差小于0.2%,基于该电路的精密神经阈值刺激仪经临床试用,取得了满意的效果.结论实践证明,该电路具有构思巧妙,原理简单,易与微处理器接口匹配等优点,可用于其它生物电信号和低频率不规则信号测量以及诸多测控系统中.

  6. The value of multifrequency bioelectrical impedance analysis on therapy sufficiency estimation in peritoneal dialysis patients%多频生物电阻抗技术在腹膜透析患者透析充分性评估中的价值

    Institute of Scientific and Technical Information of China (English)

    沈芳媛; 包蓓艳

    2012-01-01

    目的 应用多频生物电阻抗分析法(MBIA)评价腹膜透析患者的人体组成,并与腹膜透析充分性(Kt/V)相比较.方法 选择腹膜透析患者76例,按体质指数标准分为消瘦组、正常组、超重肥胖组.采用人体成分分析仪测量体重(WT)、体质指数(BMI)、总体水(TBW)、细胞外液(ECW)、细胞内液(ICW)、脂肪组织(FM)、非脂肪组织(FFM),同时计算尿素清除率(Kt/V).结果 从消瘦组、正常组到超重肥胖组,人体组成各指标逐级递增,各组间比较差异均有高度统计学意义(P<0.01).超重肥胖组Kt/V明显低于正常组(P<0.01).Kt/V与BMI、TBW、ECW、ICW、FM 、FFM均呈负相关(P< 0.05或P< 0.01).结论 不同BMI的腹膜透析患者的人体组成变化明显,MBIA对评估腹膜透析患者体液平衡状态及透析充分性有重要意义.

  7. The Application of Biomedical Engineering Techniques to the Diagnosis and Management of Tropical Diseases: A Review

    Directory of Open Access Journals (Sweden)

    Fatimah Ibrahim

    2015-03-01

    Full Text Available This paper reviews a number of biomedical engineering approaches to help aid in the detection and treatment of tropical diseases such as dengue, malaria, cholera, schistosomiasis, lymphatic filariasis, ebola, leprosy, leishmaniasis, and American trypanosomiasis (Chagas. Many different forms of non-invasive approaches such as ultrasound, echocardiography and electrocardiography, bioelectrical impedance, optical detection, simplified and rapid serological tests such as lab-on-chip and micro-/nano-fluidic platforms and medical support systems such as artificial intelligence clinical support systems are discussed. The paper also reviewed the novel clinical diagnosis and management systems using artificial intelligence and bioelectrical impedance techniques for dengue clinical applications.

  8. The application of biomedical engineering techniques to the diagnosis and management of tropical diseases: a review.

    Science.gov (United States)

    Ibrahim, Fatimah; Thio, Tzer Hwai Gilbert; Faisal, Tarig; Neuman, Michael

    2015-01-01

    This paper reviews a number of biomedical engineering approaches to help aid in the detection and treatment of tropical diseases such as dengue, malaria, cholera, schistosomiasis, lymphatic filariasis, ebola, leprosy, leishmaniasis, and American trypanosomiasis (Chagas). Many different forms of non-invasive approaches such as ultrasound, echocardiography and electrocardiography, bioelectrical impedance, optical detection, simplified and rapid serological tests such as lab-on-chip and micro-/nano-fluidic platforms and medical support systems such as artificial intelligence clinical support systems are discussed. The paper also reviewed the novel clinical diagnosis and management systems using artificial intelligence and bioelectrical impedance techniques for dengue clinical applications.

  9. Analysis and application of analog electronic circuits to biomedical instrumentation

    CERN Document Server

    Northrop, Robert B

    2012-01-01

    All chapters include an introduction and chapter summary.Sources and Properties of Biomedical SignalsSources of Endogenous Bioelectric SignalsNerve Action PotentialsMuscle Action PotentialsThe ElectrocardiogramOther BiopotentialsElectrical Properties of BioelectrodesExogenous Bioelectric SignalsProperties and Models of Semiconductor Devices Used in Analog Electronic Systemspn Junction DiodesMidfrequency Models for BJT BehaviorMidfrequency Models for Field-Effect TransistorsHigh-Frequency Models for Transistors and Simple Transistor AmplifiersPhotons, Photodiodes, Photoconductors, LEDs, and Las

  10. Wireless ultrasound-powered biotelemetry for implants.

    Science.gov (United States)

    Towe, Bruce C; Larson, Patrick J; Gulick, Daniel W

    2009-01-01

    A miniature piezoelectric receiver coupled to a diode is evaluated as a simple device for wireless transmission of bioelectric events to the body surface. The device converts the energy of a surface-applied ultrasound beam to a high frequency carrier current in solution. Bioelectrical currents near the implant modulate the carrier amplitude, and this signal is remotely detected and demodulated to recover the biopotential waveform. This technique achieves millivolt sensitivity in saline tank tests, and further attention to system design is expected to improve sensitivity. PMID:19964676

  11. Wireless ultrasound-powered biotelemetry for implants.

    Science.gov (United States)

    Towe, Bruce C; Larson, Patrick J; Gulick, Daniel W

    2009-01-01

    A miniature piezoelectric receiver coupled to a diode is evaluated as a simple device for wireless transmission of bioelectric events to the body surface. The device converts the energy of a surface-applied ultrasound beam to a high frequency carrier current in solution. Bioelectrical currents near the implant modulate the carrier amplitude, and this signal is remotely detected and demodulated to recover the biopotential waveform. This technique achieves millivolt sensitivity in saline tank tests, and further attention to system design is expected to improve sensitivity.

  12. Mathematical modelling of light-induced electric reaction of Cucurbita pepo L. leaves

    Directory of Open Access Journals (Sweden)

    Jan Stolarek

    2014-02-01

    Full Text Available The bioelectRIc reactions of 14-16 day old plants of pumpkin (Cucurbita pepo L. and internodal cells of Nitellopsis obtusa to the action of visible and ultraviolet light (UV-C were studied. The possibility of analyzing the bioelectric reaction of pumpkin plants induced by visible light by means of mathematical modelling using a linear differential equation of the second order was considered. The solution of this equation (positive and negative functions can, in a sufficient way, reflect the participation of H+ and CI- ions in the generation of the photoelectric response in green plant cells.

  13. 単周波数および多周波数BI法における身体組成評価の比較検討

    OpenAIRE

    大河原, 一憲; 田中, 喜代次; 中田, 由夫; 李, 東俊; 魏, 丞完; 中塘, 二三生

    2003-01-01

    The purpose of this study was to compare estimates of human body composition determined from single-frequency bioelectrical impedance methods (S-BIM) and multi-frequency bioelectrical impedance methods (M-BIM). The human body composition was assessed by dual energy X-ray absorptiometry (DEXA), 5 brands of S-BIM, and 2 brands of M-BIM. Forty-five women, aged 26-58 years, served as subjects. The S-BIM and M-BIM fat-free mass (FFM) estimates were highly correlated with the FFM measured by DEXA (...

  14. Effect of influenza-induced fever on human bioimpedance values.

    Directory of Open Access Journals (Sweden)

    Elisabetta Marini

    Full Text Available Bioelectrical impedance analysis (BIA is a widely used technique to assess body composition and nutritional status. While bioelectrical values are affected by diverse variables, there has been little research on validation of BIA in acute illness, especially to understand prognostic significance. Here we report the use of BIA in acute febrile states induced by influenza.Bioimpedance studies were conducted during an H1N1 influenza A outbreak in Venezuelan Amerindian villages from the Amazonas. Measurements were performed on 52 subjects between 1 and 40 years of age, and 7 children were re-examined after starting Oseltamivir treatment. Bioelectrical Impedance Vector Analysis (BIVA and permutation tests were applied.For the entire sample, febrile individuals showed a tendency toward greater reactance (p=0.058 and phase angle (p=0.037 than afebrile individuals, while resistance and impedance were similar in the two groups. Individuals with repeated measurements showed significant differences in bioimpedance values associated with fever, including increased reactance (p<0.001 and phase angle (p=0.007, and decreased resistance (p=0.007 and impedance (p<0.001.There are bioelectrical variations induced by influenza that can be related to dehydration, with lower extracellular to intracellular water ratio in febrile individuals, or a direct thermal effect. Caution is recommended when interpreting bioimpedance results in febrile states.

  15. Land-use and alternative bioenergy pathways for waste biomass.

    Science.gov (United States)

    Campbell, J E; Block, E

    2010-11-15

    Rapid escalation in biofuels consumption may lead to a trade regime that favors exports of food-based biofuels from tropical developing countries to developed countries. There is growing interest in mitigating the land-use impacts of these potential biofuels exports by converting biorefinery waste streams into cellulosic ethanol, potentially reducing the amount of land needed to meet production goals. This increased land-use efficiency for ethanol production may lower the land-use greenhouse gas emissions of ethanol but would come at the expense of converting the wastes into bioelectricity which may offset fossil fuel-based electricity and could provide a vital source of domestic electricity in developing countries. Here we compare these alternative uses of wastes with respect to environmental and energy security outcomes considering a range of electricity production efficiencies, ethanol yields, land-use scenarios, and energy offset assumptions. For a given amount of waste biomass, we found that using bioelectricity production to offset natural gas achieves 58% greater greenhouse gas reductions than using cellulosic ethanol to offset gasoline but similar emissions when cellulosic ethanol is used to offset the need for more sugar cane ethanol. If bioelectricity offsets low-carbon energy sources such as nuclear power then the liquid fuels pathway is preferred. Exports of cellulosic ethanol may have a small impact on the energy security of importing nations while bioelectricity production may have relatively large impacts on the energy security in developing countries.

  16. Burning water: the water footprint of biofuel-based transport

    NARCIS (Netherlands)

    Gerbens-Leenes, P.W.; Hoekstra, A.Y.

    2010-01-01

    The trend towards substitution of conventional transport fuels by biofuels requires additional water. The EU aims to replace 10 percent of total transport fuels by biofuels by 2020. This study calculates the water footprint (WF) of different transport modes using bio-ethanol, biodiesel or bio-electr

  17. 77 FR 20790 - Magnuson-Stevens Act Provisions; General Provisions for Domestic Fisheries; Application for...

    Science.gov (United States)

    2012-04-06

    ..., bioelectrical impedance analysis (BIA), food habits, and genetic research. The yellowtail flounder retained... for maturity, fecundity, BIA, food habits, and genetic research. The summer flounder retained would...--whole fish would be retained for maturity, fecundity, BIA, food habits, and genetic research. The...

  18. The flat-plate plant-microbial fuel cell: the effect of a new design on internal resistances

    NARCIS (Netherlands)

    Helder, M.; Strik, D.P.B.T.B.; Hamelers, H.V.M.; Buisman, C.J.N.

    2012-01-01

    Due to a growing world population and increasing welfare, energy demand worldwide is increasing. To meet the increasing energy demand in a sustainable way, new technologies are needed. The Plant-Microbial Fuel Cell (P-MFC) is a technology that could produce sustainable bio-electricity and help meeti

  19. Competition between biomass and food production in the presence of energy policies: a partial equilibrium analysis

    Energy Technology Data Exchange (ETDEWEB)

    Ignaciuk, A.; Voehringer, F.; Ruijs, A.; van Ierland, E.C. [Environmental Economics and Natural Resources Group, Wageningen University, PO Box 8130, 6700 EW Wageningen (Netherlands)

    2006-07-15

    Bioenergy has several advantages over fossil fuels. For example, it delivers energy at low net CO{sub 2} emission levels and contributes to sustaining future energy supplies. The concern, however, is that an increase in biomass plantations will reduce the land available for agricultural production. The aim of this study is to investigate the effect of taxing conventional electricity production or carbon use in combination with subsidizing biomass or bioelectricity production on the production of biomass and agricultural commodities and on the share of bioelectricity in total electricity production. We develop a partial equilibrium model to illustrate some of the potential impacts of these policies on greenhouse gas emissions, land reallocation and food and electricity prices. As a case study, we use data for Poland, which has a large potential for biomass production. Results show that combining a conventional electricity tax of 10% with a 25% subsidy on bioelectricity production increases the share of bioelectricity to 7.5%. Under this policy regime, biomass as well as agricultural production increase. A carbon tax that gives equal net tax yields, has better environmental results, however, at higher welfare costs and resulting in 1% to 4% reduction of agricultural production. (author)

  20. The functional state of the cardiovascular system in adolescents aged 16-18 born from the parents who participated in Chornobyl accident clean-up

    International Nuclear Information System (INIS)

    The state of the cardiovascular system of the adolescents aged 16-18 born from the parents who participated in Chornobyl accident clean-up was characterized by a high incidence of myocardium bioelectric activity disorders, presence of congenital small heart defects, widening of the left ventricle cavity, reduction of contractile function and myocardium tolerance to physical load.

  1. Short-Term Effects of Kinesio Taping and Cross Taping Application in the Treatment of Latent Upper Trapezius Trigger Points: A Prospective, Single-Blind, Randomized, Sham-Controlled Trial

    Directory of Open Access Journals (Sweden)

    Tomasz Halski

    2015-01-01

    Full Text Available Kinesio taping (KT may be a new treatment in patients with myofascial trigger points (MTrPs. A new method available for taping practitioners is cross taping (CT. The main objective was to determine how CT, KT, and medical adhesive tape (sham group affect the subjective assessment of resting bioelectrical activity and pain of the upper trapezius muscle (UT in patients with MTrPs. 105 volunteers were recruited to participate. The primary outcome was resting bioelectrical activity of UT muscle as assessed by surface electromyography (sEMG in each group and pain intensity on a visual analog scale (VAS. Assessments were collected before and after intervention and after the 24-hours follow-up. No significant differences were observed in bioelectrical activity of UT between pre-, post-, and follow-up results. In three groups patients had significantly lower pain VAS score after the intervention (CT—p<0.001, KT—p<0.001, and sham—p<0.01. The Kruskal-Wallis ANOVA showed no significant differences in almost all measurements between groups. The application of all three types of tapes does not influence the resting bioelectrical activity of UT muscle and may not lead to a reduction in muscle tone in the case of MTrPs.

  2. Short-Term Effects of Kinesio Taping and Cross Taping Application in the Treatment of Latent Upper Trapezius Trigger Points: A Prospective, Single-Blind, Randomized, Sham-Controlled Trial

    Science.gov (United States)

    Halski, Tomasz; Ptaszkowski, Kuba; Słupska, Lucyna; Paprocka-Borowicz, Małgorzata; Dymarek, Robert; Taradaj, Jakub; Bidzińska, Gabriela; Marczyński, Daniel; Cynarska, Aleksandra; Rosińczuk, Joanna

    2015-01-01

    Kinesio taping (KT) may be a new treatment in patients with myofascial trigger points (MTrPs). A new method available for taping practitioners is cross taping (CT). The main objective was to determine how CT, KT, and medical adhesive tape (sham group) affect the subjective assessment of resting bioelectrical activity and pain of the upper trapezius muscle (UT) in patients with MTrPs. 105 volunteers were recruited to participate. The primary outcome was resting bioelectrical activity of UT muscle as assessed by surface electromyography (sEMG) in each group and pain intensity on a visual analog scale (VAS). Assessments were collected before and after intervention and after the 24-hours follow-up. No significant differences were observed in bioelectrical activity of UT between pre-, post-, and follow-up results. In three groups patients had significantly lower pain VAS score after the intervention (CT—p tapes does not influence the resting bioelectrical activity of UT muscle and may not lead to a reduction in muscle tone in the case of MTrPs. PMID:26491458

  3. Body composition and energy metabolism in elderly people.

    NARCIS (Netherlands)

    Visser, M.

    1995-01-01

    This thesis describes several studies related to the three components of energy balance in elderly people: body composition, energy expenditure, and energy intake.Body composition. The applicability of the body mass index, skinfold thickness method, and multi-frequency bioelectrical impedance was te

  4. Treatment of experimental ulcerative colitis.

    Science.gov (United States)

    Lazebnik, L B; Lychkova, A E; Knyazev, O V

    2012-10-01

    The effects of infliximab, an anticytokine drug, on the course of inflammatory process was studied on the model of ulcerative colitis induced by injection of picrylsulfonic acid. Infliximab prevented the development of toxic dilatation and a drop of bioelectric activity of smooth muscles via maintenance of activity of the intramural nervous system neurons. PMID:23113311

  5. Biomass and multi-product crops for agricultural and energy production - an AGE analysis

    NARCIS (Netherlands)

    Ignaciuk, A.; Dellink, R.B.

    2006-01-01

    By-products from agriculture and forestry can contribute to production of clean and cheap (bio)electricity. To assess the role of such multi-product crops in the response to climate policies, we present an applied general equilibrium model with special attention to biomass and multi-product crops. T

  6. Multi-Product Crops for Agricultural and Energy Production : an AGE Analysis for Poland

    NARCIS (Netherlands)

    Ignaciuk, A.; Dellink, R.B.

    2005-01-01

    By-products from agriculture and forestry can contribute to production of clean and cheap (bio)electricity. To assess the role of such multi-product crops in the response to climate policies, we present an applied general equilibrium model with special attention to biomass and multi-product crops fo

  7. The Flatworm Macrostomum lignano Is a Powerful Model Organism for Ion Channel and Stem Cell Research

    NARCIS (Netherlands)

    Simanov, Daniil; Mellaart-Straver, Imre; Sormacheva, Irina; Berezikov, Eugene

    2012-01-01

    Bioelectrical signals generated by ion channels play crucial roles in many cellular processes in both excitable and nonexcitable cells. Some ion channels are directly implemented in chemical signaling pathways, the others are involved in regulation of cytoplasmic or vesicular ion concentrations, pH,

  8. Genome‐wide analysis reveals conserved transcriptional responses downstream of resting potential change in Xenopus embryos, axolotl regeneration, and human mesenchymal cell differentiation

    Science.gov (United States)

    Pai, Vaibhav P.; Martyniuk, Christopher J.; Echeverri, Karen; Sundelacruz, Sarah; Kaplan, David L.

    2015-01-01

    Abstract Endogenous bioelectric signaling via changes in cellular resting potential (V mem) is a key regulator of patterning during regeneration and embryogenesis in numerous model systems. Depolarization of V mem has been functionally implicated in dedifferentiation, tumorigenesis, anatomical re‐specification, and appendage regeneration. However, no unbiased analyses have been performed to understand genome‐wide transcriptional responses to V mem change in vivo. Moreover, it is unknown which genes or gene networks represent conserved targets of bioelectrical signaling across different patterning contexts and species. Here, we use microarray analysis to comparatively analyze transcriptional responses to V mem depolarization. We compare the response of the transcriptome during embryogenesis (Xenopus development), regeneration (axolotl regeneration), and stem cell differentiation (human mesenchymal stem cells in culture) to identify common networks across model species that are associated with depolarization. Both subnetwork enrichment and PANTHER analyses identified a number of key genetic modules as targets of V mem change, and also revealed important (well‐conserved) commonalities in bioelectric signal transduction, despite highly diverse experimental contexts and species. Depolarization regulates specific transcriptional networks across all three germ layers (ectoderm, mesoderm, and endoderm) such as cell differentiation and apoptosis, and this information will be used for developing mechanistic models of bioelectric regulation of patterning. Moreover, our analysis reveals that V mem change regulates transcripts related to important disease pathways such as cancer and neurodegeneration, which may represent novel targets for emerging electroceutical therapies. PMID:27499876

  9. Miniature electrometer preamplifier effectively compensates for input capacitance

    Science.gov (United States)

    Burrous, C. N.; Deboo, G. J.

    1966-01-01

    Negative capacitance preamplifier using a dual MOS /Metal Oxide Silicon/ transistor in conjunction with bipolar transistors is used with intracellular microelectrodes in recording bioelectric potentials. Applications would include use as a pickup plate video amplifier in storage tube tests and for pH and ionization chamber measurements.

  10. Finite element simulations of magnetomyograms of rat skeletal muscle

    OpenAIRE

    Rutten, W.L.C.; Wildeman, A; Rozijn, T H

    1990-01-01

    The following topics are dealt with: biosensors; cardiology; processing of bioelectric signals; biomedical application of automatic control; lasers and electrooptics; computers in medicine; expert systems in medicine; fractals in biomedical engineering; neural networks; biophysical and biochemical measurements; molecular electronics; biorobotics; critical-care monitoring and control; sleep and respiratory control dynamics; bioengineering in dentistry; biomaterials; biomechanics; neuromuscular...

  11. Clinical biophysics

    Energy Technology Data Exchange (ETDEWEB)

    Anbar, M.; Spangler, R.A.; Scott, P.

    1985-01-01

    Chapters are included on clinical decision making, principles of biomedical engineering, computers and their medical uses, clinical radiobiology, diagnostic x-ray radiology, clinical applications of ultrasonics, nuclear medicine, NMR imaging, diagnostic imaging, bioelectric techniques in diagnosis and therapy, biophysical aspects of the clinical laboratory, and biophysical aspects of modern surgery.

  12. Quantitative CT: Associations between Emphysema, Airway Wall Thickness and Body Composition in COPD

    DEFF Research Database (Denmark)

    Rutten, Erica P A; Grydeland, Thomas B; Pillai, Sreekumar G;

    2011-01-01

    , CT scans were performed to determine emphysema (%LAA), airway wall thickness (AWT-Pi10), and lung mass. Muscle wasting based on FFMI was assessed by bioelectrical impedance. In both the men and women with COPD, FFMI was negatively associated with %LAA. FMI was positively associated with AWT-Pi10 in...

  13. The water footprint of biofuel-based transport

    NARCIS (Netherlands)

    Gerbens-Leenes, P.W.; Hoekstra, A.Y.

    2011-01-01

    The EU target to replace 10 percent of transport fuels by renewables by 2020 requires additional water. This study calculates water footprints (WFs) of transport modes using first generation bio-ethanol, biodiesel or bio-electricity and of European transport if 10 percent of transport fuels is bio-e

  14. Information Technologies in the Assessment of Violations of Cognitive Functions

    Directory of Open Access Journals (Sweden)

    Vitaly P. Omelchenko

    2013-01-01

    Full Text Available This article is about application of information technologies for an assessment of violations of cognitive functions at patients with diabetic and discirculatorencephalopathies. Results of the mathematical analysis of bioelectric activity of a brain of examinees are considered, the most significant factors reflecting existence of cognitive violations are revealed

  15. Determinants of poor 6-min walking distance in patients with COPD: the ECLIPSE cohort

    DEFF Research Database (Denmark)

    Spruit, Martijn A; Watkins, Michael L; Edwards, Lisa D;

    2010-01-01

    identify clinical determinants of a poor 6-min walking distance (<350 m) in patients with COPD. METHODS: 1795 individuals with a diagnosis of COPD underwent spirometry; bio-electrical impedance analysis; low-dose computed tomography scans of the chest; 6MWT; ATS-DLD co-morbidity questionnaire; Center for...

  16. IGF-I at 9 and 36 months of age — relations with body composition and diet at 3 years — the SKOT cohort

    DEFF Research Database (Denmark)

    Ejlerskov, Katrine Tschentscher; Larnkjær, A.; Pedersen, D.;

    2014-01-01

    the prospective cohort study, SKOT, were examined at 9 and 36 months with anthropometry, bioelectrical impedance (36 months), 7-day food records and blood analysis of IGF-I and IGFBP-3 by chemiluminescent immunometric assay. Results IGF-I at 36 months (n = 229) was positively correlated with 9 months values...

  17. Assessing Body Composition of Children and Adolescents Using Dual-Energy X-Ray Absorptiometry, Skinfolds, and Electrical Impedance

    Science.gov (United States)

    Mooney, Angela; Kelsey, Laurel; Fellingham, Gilbert W.; George, James D.; Hager, Ron L.; Myrer, J. William; Vehrs, Pat R.

    2011-01-01

    To determine the validity and reliability of percent body fat estimates in 177 boys and 154 girls between 12-17 years of age, percent body fat was assessed once using dual-energy X-ray absorptiometry and twice using the sum of two skinfolds and three bioelectrical impedance analysis devices. The assessments were repeated on 79 participants on a…

  18. Exploring redox-mediating characteristics of textile dye-bearing microbial fuel cells: thionin and malachite green.

    Science.gov (United States)

    Chen, Bor-Yann; Xu, Bin; Qin, Lian-Jie; Lan, John Chi-Wei; Hsueh, Chung-Chuan

    2014-10-01

    Prior studies indicated that biodecolorized intermediates of azo dyes could act as electron shuttles to stimulate wastewater decolorization and bioelectricity generation (WD&BG) in microbial fuel cells (MFCs). This study tended to explore whether non-azo textile dyes (i.e., thionin and malachite green) could also own such redox-mediating capabilities for WD&BG. Prior findings mentioned that OH and/or NH2 substitute-containing auxochrome compounds (e.g., 2-aminophenol and 1,2-dihydroxybenzene) could effectively mediate electron transport in MFCs for simultaneous WD&BG. This work clearly suggested that the presence of electron-mediating textile dyes (e.g., thionin and malachite green (MG)) in MFCs is promising to stimulate color removal and bioelectricity generation. That is, using MFCs as operation strategy for wastewater biodecolorization is economically promising in industrial applications due to autocatalytic acceleration of electron-flux for WD&BG in MFCs.

  19. Neotropical electric fishes (Gymnotiformes) as model organisms for bioassays

    Institute of Scientific and Technical Information of China (English)

    Milena Ferreira; Isac Silva de Jesus; Eliana Feldberg; JoséAntônioAlves-Gomes

    2015-01-01

    Electric fishes (Gymnotiformes) inhabit Central and South America and form a relatively large group with more than 200 species. Besides a taxonomic challenge due to their still unresolved systematic, wide distribution and the variety of habitats they occupy, these fishes have been intensively studied due to their peculiar use of bioelectricity for electrolocation and communication. Conventional analysis of cells, tissues and organs have been complemented with the studies on the electric organ discharges of these fishes. This review compiles the results of 13 bioassays developed during the last 50 years, which used the quickness, low costs and functionality of the bioelectric data collection of Gymnotiformes to evaluate the effects of environmental contaminants and neuroactive drugs.

  20. Direct extraction of photosynthetic electrons from single algal cells by nanoprobing system.

    Science.gov (United States)

    Ryu, WonHyoung; Bai, Seoung-Jai; Park, Joong Sun; Huang, Zubin; Moseley, Jeffrey; Fabian, Tibor; Fasching, Rainer J; Grossman, Arthur R; Prinz, Fritz B

    2010-04-14

    There are numerous sources of bioenergy that are generated by photosynthetic processes, for example, lipids, alcohols, hydrogen, and polysaccharides. However, generally only a small fraction of solar energy absorbed by photosynthetic organisms is converted to a form of energy that can be readily exploited. To more efficiently use the solar energy harvested by photosynthetic organisms, we evaluated the feasibility of generating bioelectricity by directly extracting electrons from the photosynthetic electron transport chain before they are used to fix CO(2) into sugars and polysaccharides. From a living algal cell, Chlamydomonas reinhardtii, photosynthetic electrons (1.2 pA at 6000 mA/m(2)) were directly extracted without a mediator electron carrier by inserting a nanoelectrode into the algal chloroplast and applying an overvoltage. This result may represent an initial step in generating "high efficiency" bioelectricity by directly harvesting high energy photosynthetic electrons. PMID:20201533

  1. [A layer-by-layer analysis of the components of the thalamocortical responses of the rabbit sensorimotor cortex in ontogeny].

    Science.gov (United States)

    Shimko, I A

    1991-01-01

    The data obtained in the paper showed that complex dynamics of changes of spatial-temporary situation of heterocomponent thalamocortical responses (TCR) at passing the sensorimotor cortex (SMC) was conditioned by the properties of electrogenesis of each TCR component, age and frequency of stimulation of ventroposterolateral (VPL) thalamus nucleus transformation of electric profile of the second positive component (PC-2) of the TCR at passing SMC might testify to algebraic summation in this component of bioelectric processes of several generation sources (invertible and non-invertible PC-2). The revealed properties of ontogenetic dynamics of the bioelectric fields profiles of the third negative component (NC-3) of the TCR might be the consequence of the age stages of the development and change of embryonal mechanisms of electrogenesis of the definitive ones in extremely similar negativities.

  2. Primary report of noninvasive impedance monitoring of cerebral hematoma and edema in patients with intracerebral hemorrhage

    Institute of Scientific and Technical Information of China (English)

    Xia Yi Lu; Dong Wei-Wei; Yang Hao; Long Men; Yang Hua

    2000-01-01

    Background and Objective Brain edema is one of the most important clinical process in many diseases. Tissue impedance monitoring offers a non-invasive, bedside, rapid, and reliable technique for the monitoring of the brain edema. Methods We use a bioelectrical impedance(BEI) monitoring unit to record the brain impedance in the healthy volunteer and the patients with intracerebral hemorrhage. Percent of BEI variations were calculation. Results and Conclusions Brain BEI haven f any difference between both hemispheres in normal ones. In 48hrs, BEI value at hematoma-side was obviously decreased; after 48hrs, BEI value was obviously increased and continue to tenth day. Brain bioelectrical impedance monitoring, particularly noninvasively, is a first time in this field. The primary results show brain BEI could reflect the evolution of cerebral hematoma and edema.

  3. [Endurance and Fatigue Caused by Local Muscular Performance in Skilled Athletes].

    Science.gov (United States)

    Popova, T V; Koryukalov, Y I; Kourova, O G

    2015-01-01

    It was the objective of this research to study the functional parameters of endurance and performance and the brain electrobiological activity during local antebrachial muscle work performance among skilled athletes and unfit people aged 18-23. We examined performance and the brain bioelectrical activity changes at local muscle work by means of an ergograph until fatigue. Our results suggested that local performance increased the spectral power of slow alpha- and theta waves as the fatigue set in, but these changes developed slower and were manifested later in the athletes than in the unfit people. Besides, tired athletes' EEGs showed alpha waves synchronization and only demonstrated a decrease in low- and high frequency beta waves indexes. Athletes show higher performance and lower fatigability if compared to unfit people during local performance, also proved by the EEG bioelectrical changes. PMID:26859997

  4. Biomechanical bases of rehabilitation of children with cerebral palsy

    Science.gov (United States)

    Davlet'yarova, K. V.; Korshunov, S. D.; Kapilevich, L. V.

    2015-11-01

    Biomechanical analysis and the study results of children's with cerebral palsy (CP) muscles bioelectrical activity while walking on a flat surface are represented. Increased flexion in the hip and shoulder joints and extension in the elbow joint in children with cerebral palsy were observed, with the movement of the lower limbs had less smooth character in comparison with the control group. Herewith, the oscillation amplitude was significantly increased, and the frequency in the m. gastrocnemius and m. lateralis was decreased. It was shown, that the dynamic stereotype of walking in children with cerebral palsy was characterized by excessive involvement of m. gastrocnemius and m.latissimus dorsi in locomotion. Thus, resulting biomechanical and bioelectrical parameters of walking should be considered in the rehabilitation programs development.

  5. Bioenergy in Brazil and Europe: a comparative analysis; Bioenergia no Brasil e na Europa: uma analise comparativa

    Energy Technology Data Exchange (ETDEWEB)

    Castro, Nivalde Jose de [Universidade Federal do Rio de Janeiro (IE/UFRJ), RJ (Brazil). Inst. de Economia], e-mail: nivalde@ie.ufrj.br; Dantas, Guilherme de Azevedo [Universidade Federal do Rio de Janeiro (GESEL/UFRJ), RJ (Brazil). Grupo de Estudos do Setor Eletrico], e-mail: guilhermecrvg@yahoo.com.br

    2008-07-01

    A higher application of bioenergy is one of the existing ways to adequate the necessity of an expansion in the energy supply with the mitigation of global warming. The consumption of biofuel in the transport sector is the most usual and important use of biomass, however, bioenergy may also have a relevant contribution to the world electrical matrix. A comparative analysis shows that Brazil has consolidate the usage of biofuel while Europe is having problems to accomplish the biofuels levels established in the European Union guidelines. However, some european countries are developing their bioelectrical generation potential in a much more efficient way than Brazil. Therefore , brazilian policies to support bioelectricity should observe the successful instruments applied in Europe. (author)

  6. High-resolution non-contact measurement of the electrical activity of plants in situ using optical recording.

    Science.gov (United States)

    Zhao, Dong-Jie; Chen, Yang; Wang, Zi-Yang; Xue, Lin; Mao, Tong-Lin; Liu, Yi-Min; Wang, Zhong-Yi; Huang, Lan

    2015-01-01

    The limitations of conventional extracellular recording and intracellular recording make high-resolution multisite recording of plant bioelectrical activity in situ challenging. By combining a cooled charge-coupled device camera with a voltage-sensitive dye, we recorded the action potentials in the stem of Helianthus annuus and variation potentials at multiple sites simultaneously with high spatial resolution. The method of signal processing using coherence analysis was used to determine the synchronization of the selected signals. Our results provide direct visualization of the phloem, which is the distribution region of the electrical activities in the stem and leaf of H. annuus, and verify that the phloem is the main action potential transmission route in the stems of higher plants. Finally, the method of optical recording offers a unique opportunity to map the dynamic bioelectrical activity and provides an insight into the mechanisms of long-distance electrical signal transmission in higher plants. PMID:26333536

  7. [Camphor preparations in the overall therapy of cerebral infarct].

    Science.gov (United States)

    Natiazhkina, G M; Gorbacheva, F E; Kats, E I; Kvasov, V T

    1980-01-01

    The authors studied the platelet functional properties and the brain bioelectric activity in 20 patients with acute cerebrovascular diseases before and after subcutaneous injection of 2.0 ml of racemic camphor T, as well as before and after oral taking of monobromated camphor in a dose of 0.5 g 3 times a day. The platelet aggregation was examined by the method of Born (1962) with automatic recording of aggregatograms. The brain bioelectric activity was examined using an Alvar electroencephalograph. As a result, the authors discovered an inhibitory effect of camphor preparations on the platelet aggregation. Racemic camphor T and monobromated camphor were found to produce a stimulant effect on the brain. PMID:6986733

  8. L-Dex Ratio in Detecting Breast Cancer-Related Lymphedema: Reliability, Sensitivity, and Specificity

    OpenAIRE

    Mei R. Fu; Cleland, Charles M.; Guth, Amber A.; Kayal, Maia; Haber, Judith; Cartwright, Francis; Kleinman, Robin; Kang, Yang; Scagliola, Joan; Axelrod, Deborah

    2013-01-01

    Advances in bioelectrical impedance analysis (BIA) permit the assessment of lymphedema by directly measuring lymph fluid changes. The purpose of the study was to examine the reliability, sensitivity, and specificity of cross-sectional assessment of BIA in detecting lymphedema in a large metropolitan clinical setting. BIA was used to measure lymph fluid changes. Limb volume by sequential circumferential tape measurement was used to validate the presence of lymphedema. Data were collected from ...

  9. Rhesus monkey is a new model of secondary lymphedema in the upper limb

    OpenAIRE

    Wu, Guojun; Xu, Hao; Zhou, Wenhong; Yuan, Xianshun; Yang, Zhe; Yang, Qing; Ding, Feng; Meng, Zhigang; Liang, Weili; Geng, Chong; Gao, Ling; Tian, Xingsong

    2014-01-01

    Objective: This study is to establish the rhesus monkey model of lymphedema in the upper limbs, and assess the suitability of this model. Methods: An animal model of lymphedema was established by the combined irradiation and surgical techniques in the upper limbs of these rhesus monkeys. Physical examination, high-resolution MR lymphangiography, bioelectrical impedance analysis (BIA), and immunohistochemical staining were performed to determine the severity of the edema in the upper limbs of ...

  10. Performance of pilot-scale microbial fuel cells treating wastewater with associated bioenergy production in the Caribbean context

    OpenAIRE

    Tota-Maharaj, Kiran; Paul, Parneet

    2015-01-01

    Microbial fuel cell (MFC) technology represents a form of renewable energy that generates bioelectricity from what would otherwise be considered a waste stream. MFCs may be ideally suited to the small island developing state (SIDS) context, such as Trinidad and Tobago where seawater as the main electrolyte is readily available and economical renewable and sustainable electricity is also deemed a priority. Hence this project tested two identical laboratory-scaled MFC systems that were specific...

  11. Burning water: the water footprint of biofuel-based transport

    OpenAIRE

    Gerbens-Leenes, P.W.; Hoekstra, A.Y.

    2010-01-01

    The trend towards substitution of conventional transport fuels by biofuels requires additional water. The EU aims to replace 10 percent of total transport fuels by biofuels by 2020. This study calculates the water footprint (WF) of different transport modes using bio-ethanol, biodiesel or bio-electricity and of European transport if 10 percent of transport fuels is replaced by bio-ethanol. We compare results for Europe with similar goals for other regions (Africa, Asia, Latin America, the for...

  12. Einfluss krankheitsassoziierter Mangelernährung auf Körperzusammensetzung und Prognose

    OpenAIRE

    Pirlich, Matthias

    2010-01-01

    Disease-related malnutrition is a frequent clincal problem with severe medical and economic impact. This work summarizes studies on body composition analysis, risk factors, prevalence and prognostic impact of malnutrition. The diagnosis of malnutrition in patients with chronic liver disease is hampered by hyperhydration and requires body composition analysis. Using four different methods for body composition analysis (total body potassium counting, anthropometry, bioelectrical impedance analy...

  13. Body Image v kontextu soudobé společnosti

    OpenAIRE

    Rolínek, Igor

    2008-01-01

    The thesis focuses on body image - defines the main characteristics of this area, describes cultural influences and body image history and explains basic quantitative values (Body Mass Index, Waist Hip Ratio, Bioelectrical Impedance Analysis). Furthemore the thesis deals with media influence on body ideal formation process, especially in gay subculture. The research part explores recent situation of body image in gay subculture compared with heterosexual males. This section includes the conte...

  14. Fat‐free mass and calf circumference as body composition indices to determine non‐exercise activity thermogenesis in patients with diabetes

    OpenAIRE

    Isobe, Yuki; Sakurai, Masaru; Kita, Yuki; Takeshita, Yumie; Misu, Hirofumi; Kaneko, Shuichi; Takamura, Toshinari

    2015-01-01

    Abstract Aims/Introduction To investigate the clinical and anthropometrical parameters that are associated with non‐exercise activity thermogenesis that is composed of basal energy expenditure (BEE) and diet‐induced thermogenesis (DIT) in patients with diabetes. Materials and Methods Body composition was assessed using bioelectrical impedance, and BEE and DIT were measured using indirect calorimetry in 40 Japanese patients with diabetes. Results BEE correlated positively with bodyweight, body...

  15. Fat-free mass and calf circumference as body composition indices to determine non-exercise activity thermogenesis in patients with diabetes

    OpenAIRE

    Isobe, Yuki; Sakurai, Masaru; Kita, Yuki; Takeshita, Yumie; Misu, Hirofumi; Kaneko, Shuichi; Takamura, Toshinari

    2016-01-01

    Aims/Introduction: To investigate the clinical and anthropometrical parameters that are associated with non-exercise activity thermogenesis that is composed of basal energy expenditure (BEE) and diet-induced thermogenesis (DIT) in patients with diabetes. Materials and Methods: Body composition was assessed using bioelectrical impedance, and BEE and DIT were measured using indirect calorimetry in 40 Japanese patients with diabetes. Results: BEE correlated positively with bodyweight, body mass ...

  16. Changes in EEG during Ultralong Running

    OpenAIRE

    Doppelmayr, M.; Sauseng, P.; Doppelmayr, H.; Mausz, I.

    2012-01-01

    There are only a few studies using human electroencephalograms (EEGs) to investigate bioelectrical changes in the brain during exercise (running or cycling). These studies report an increase in EEG alpha amplitude during and immediately after exercise. However, only exercises within a relatively short time interval of approximately 1 hour have been investigated. Thus, we focussed on long-lasting exercise and report three single case studies, performed on the same participant, during extended ...

  17. Frequency response of an electric equivalent circuit for a skin type system

    OpenAIRE

    F. Gómez-Aguilar; J. Bernal-Alvarado; J. Rosales-García; M. Guía-Calderón; T Córdova-Fraga; M. Sosa-Aquino

    2011-01-01

    In the present work we consider a theoretical representation of an electrical circuit equivalent to a multilayer biological system. The proposed system is of the skin type, containing epidermis, dermis and the subcutaneous tissue. Electrical circuit theory is used, and the behavior of the system is shown in the form of Nyquist and Bode plots. The proposed theoretical approach is a general treatment to describe the bioelectrical transport in a three-layered system, especially in the ele...

  18. Phase angle as a nutritional evaluation tool in all stages of chronic liver disease Ángulo de fase como una herramienta para evaluar el estado nutricional en todas las etapas de la enfermedad hepática crónica

    OpenAIRE

    W. A. F. Peres; D. F. Lento; K. Baluz; Ramalho, A

    2012-01-01

    Introduction: Malnutrition is commonly and frequently under-diagnosed in clinical settings in patients with chronic liver disease (CLD) due to the limitations of nutritional evaluation methods in this population. We hypothesized that the bioelectrical impedance analysis derived phase angle (BIA-derived PhA) might be considered as a nutritional indicator in CLD since it represents either cell death or malnutrition characterized by changes in cellular membrane integrity. Objective: The aim of t...

  19. Biophysical aspects of the influence of electromagnetic fields (EMF) on the human body Influencia de los campos electromagnéticos en el organismo humano: aspectos biofísicos

    OpenAIRE

    Napaleon Hernández

    1993-01-01

     

    Some historical aspects of biomagnetism and of the various steps that led to the development of bioelectricity and electro technique are summarized. Alterations observed in individuals working for long periods of time in contact with artificial EMF are described as well as the correlation between natural EMF and accidentality. The utilization of EMF for therapeutic purposes ...

  20. Biomedical engineering fundamentals

    CERN Document Server

    Bronzino, Joseph D

    2014-01-01

    Known as the bible of biomedical engineering, The Biomedical Engineering Handbook, Fourth Edition, sets the standard against which all other references of this nature are measured. As such, it has served as a major resource for both skilled professionals and novices to biomedical engineering.Biomedical Engineering Fundamentals, the first volume of the handbook, presents material from respected scientists with diverse backgrounds in physiological systems, biomechanics, biomaterials, bioelectric phenomena, and neuroengineering. More than three dozen specific topics are examined, including cardia

  1. [Music therapy and "brain music": state of the art, problems and perspectives].

    Science.gov (United States)

    2013-01-01

    Recent literature on the problem of interaction between music and the brain is reviewed and summarized. Mechanisms and effects of two most popular music therapy applications are picked out, including music listening and music making. Special attention is paid to relatively new line of investigations that is called "music of the brain" and deals with transformation of bioelectric processes of human organism into music. Unresolved questions of music therapy are identified and some promising lines of future investigations are delineated. PMID:25508092

  2. Sarcopenia: clinical evaluation, biological markers and other evaluation tools

    OpenAIRE

    Pahor, M.; Manini,, Claudia; CESARI, M.

    2009-01-01

    Sarcopenia is characterized by a lower skeletal muscle quantity, higher fat accumulation in the muscle, lower muscle strength, and lower physical performance. The most commonly used, low cost and accessible methods to assess skeletal muscle mass include dual energy X-ray absorptiometry (DEXA), anthropometry and bioelectrical impedance analysis (BIA). Magnetic resonance imaging (MRI), computerized tomography (CT) and creatinine excretion are the most specific golden standards for assessing mus...

  3. Body composition in Egyptian Turner syndrome girls

    OpenAIRE

    Moushira Erfan Zaki; Afifi, Hanan H

    2013-01-01

    Objective: This cross-sectional study was undertaken to construct the new body fat % curve and provide body composition reference data for adolescent girls with Turner syndrome (TS). They diagnosed cytogenetically by blood karyotyping and not treated with growth hormone (GH). Materials and Methods: The study included 70 TS girls from age 13 years to age 17 years. Body composition was measured by bioelectrical impedance. Smoothed centile charts were derived by using the least mean square (...

  4. Biofuel for Energy Security: An Examination on Pyrolysis Systems with Emissions from Fertilizer and Land-Use Change

    OpenAIRE

    Chih-Chun Kung; Hualin Xie; Tao Wu; Shih-Chih Chen

    2014-01-01

    One of the most important concerns facing Taiwan is lack of energy security. The study examines to what extent the Taiwan energy security can be enhanced through bioenergy production and how bioenergy affects net greenhouse gases emissions. Ethanol, conventional bioelectricity and pyrolysis based electricity are analyzed and emissions from fertilizer use and land use change are also incorporated. The study employs the Modified Taiwan Agricultural Sector Model (MTASM) for economic and environm...

  5. Body composition and energy metabolism in elderly people.

    OpenAIRE

    Visser, M.

    1995-01-01

    This thesis describes several studies related to the three components of energy balance in elderly people: body composition, energy expenditure, and energy intake.Body composition. The applicability of the body mass index, skinfold thickness method, and multi-frequency bioelectrical impedance was tested in elderly men and women. The first two methods predicted body fat in elderly people on a group level with a mean prediction error of 5%. The impedance method predicted total body water (at 50...

  6. Associations of Sarcopenia and Sarcopenic Obesity With Metabolic Syndrome Considering Both Muscle Mass and Muscle Strength

    OpenAIRE

    Lee, Jihye; Hong, Yeon-Pyo; Shin, Hyun Ju; Lee, Weonyoung

    2015-01-01

    Objectives: We investigated the associations of sarcopenia-defined both in terms of muscle mass and muscle strength-and sarcopenic obesity with metabolic syndrome. Methods: Secondary data pertaining to 309 subjects (85 men and 224 women) were collected from participants in exercise programs at a health center in a suburban area. Muscle mass was measured using bioelectrical impedance analysis, and muscle strength was measured via handgrip strength. Sarcopenia based on muscle mass alone was def...

  7. Percent body fat is a better predictor of cardiovascular risk factors than body mass index

    OpenAIRE

    Qiang Zeng; Sheng-Yong Dong; Xiao-Nan Sun; Jing Xie; Yi Cui

    2012-01-01

    The objective of the present study was to evaluate the predictive values of percent body fat (PBF) and body mass index (BMI) for cardiovascular risk factors, especially when PBF and BMI are conflicting. BMI was calculated by the standard formula and PBF was determined by bioelectrical impedance analysis. A total of 3859 ambulatory adult Han Chinese subjects (2173 males and 1686 females, age range: 18-85 years) without a history of cardiovascular diseases were recruited from February to Septem...

  8. Functional Capacity of Oldest Old Living in a Long-stay Institution in Rio De Janeiro, Brazil

    OpenAIRE

    Dias, Fabiano Moura; Costa, Susana Ortiz; Pereira de Freitas, Jeter; Pinto, Adriana da Costa Rocha; Vigário, Patrícia dos Santos; Mainenti, Míriam Raquel Meira

    2014-01-01

    [Purpose] A significant increase in the number of oldest old has occurred worldwide. The aim of this study was to characterize the functional capacity of the oldest old residents in a long-stay institution in Rio de Janeiro, Brazil. [Subjects and Methods] All participants were evaluated according to the following metrics: anthropometry, body composition (bioelectrical impedance), handgrip strength, balance (Berg scale and stabilometry), ankle mobility (electrogoniometry), physical capacity (s...

  9. Large scale scenario analysis of future low carbon energy options

    International Nuclear Information System (INIS)

    In this study, we use a multi-model framework to examine a set of possible future energy scenarios resulting from R&D investments in Solar, Nuclear, Carbon Capture and Storage (CCS), Bio-fuels, Bio-electricity, and Batteries for Electric Transportation. Based on a global scenario analysis, we examine the impact on the economy of advancement in energy technologies, considering both individual technologies and the interactions between pairs of technologies, with a focus on the role of uncertainty. Nuclear and CCS have the most impact on abatement costs, with CCS mostly important at high levels of abatement. We show that CCS and Bio-electricity are complements, while most of the other energy technology pairs are substitutes. We also examine for stochastic dominance between R&D portfolios: given the uncertainty in R&D outcomes, we examine which portfolios would be preferred by all decision-makers, regardless of their attitude toward risk. We observe that portfolios with CCS tend to stochastically dominate those without CCS; and portfolios lacking CCS and Nuclear tend to be stochastically dominated by others. We find that the dominance of CCS becomes even stronger as uncertainty in climate damages increases. Finally, we show that there is significant value in carefully choosing a portfolio, as relatively small portfolios can dominate large portfolios. - Highlights: • We examine future energy scenarios in the face of R&D and climate uncertainty. • We examine the impact of advancement in energy technologies and pairs of technologies. • CCS complements Bio-electricity while most technology pairs are substitutes. • R&D portfolios without CCS are stochastically dominated by portfolios with CCS. • Higher damage uncertainty favors R&D development of CCS and Bio-electricity

  10. Electrolytic Generation of Oxygen Partially Explains Electrical Enhancement of Tobramycin Efficacy against Pseudomonas aeruginosa Biofilm

    OpenAIRE

    Stewart, Philip S.; Wattanakaroon, Wanida; Goodrum, Lu; Fortun, Susana M.; McLeod, Bruce R.

    1999-01-01

    The role of electrolysis products, including protons, hydroxyl ions, reactive oxygen intermediates, oxygen, hydrogen, and heat, in mediating electrical enhancement of killing of Pseudomonas aeruginosa biofilms by tobramycin (the bioelectric effect) was investigated. The log reduction in biofilm viable cell numbers compared to the numbers for the untreated positive control effected by antibiotic increased from 2.88 in the absence of electric current to 5.58 in the presence of electric current....

  11. Interface entre neurones et puces structurées électroniques pour la détection de potentiels d'action

    OpenAIRE

    Larramendy, Florian

    2013-01-01

    The interface man / machine had followed of many researches in biotechnology. A part of these researches concern the interconnections brain / machine. Indeed, the brain arranges numerous intellectual connections thanks to neurons. These neurons communicate between them and propagate information thanks to a "bio-electric" signal called action potential. The objective of my doctoral thesis is to measure this signal thanks to ion sensitive field effect transistor (ISFET). The ISFET process was m...

  12. Assessment and follow-up of muscle injuries in athletes by bioimpedance: Preliminary results

    OpenAIRE

    Nescolarde Selva, Lexa Digna; Yanguas Leyes, Javier; Medina Leal, Daniel; Rodas Font, Gil; Rosell Ferrer, Francisco Javier

    2011-01-01

    Mono-frequency (50 kHz) whole-body and segmental bioimpedance is measured before sport training in 14 high performance athletes. The athletes are classified in two groups according to the team sport: football and basketball. Bioelectrical impedance vector analysis (BIVA) method is used to obtain the individual whole-body impedance and 6 segmental impedance vectors in the main muscular groups in the lower- limbs. The whole-body vector is...

  13. A Three Spatial Dimension Wave Latent Force Model for Describing Excitation Sources and Electric Potentials Produced by Deep Brain Stimulation

    OpenAIRE

    Alvarado, Pablo A.; Álvarez, Mauricio A.; Orozco, Álvaro A.

    2016-01-01

    Deep brain stimulation (DBS) is a surgical treatment for Parkinson's Disease. Static models based on quasi-static approximation are common approaches for DBS modeling. While this simplification has been validated for bioelectric sources, its application to rapid stimulation pulses, which contain more high-frequency power, may not be appropriate, as DBS therapeutic results depend on stimulus parameters such as frequency and pulse width, which are related to time variations of the electric fiel...

  14. Survival of the Stillest: Predator Avoidance in Shark Embryos

    OpenAIRE

    Kempster, Ryan M.; Hart, Nathan S.; Collin, Shaun P.

    2013-01-01

    Sharks use highly sensitive electroreceptors to detect the electric fields emitted by potential prey. However, it is not known whether prey animals are able to modulate their own bioelectrical signals to reduce predation risk. Here, we show that some shark (Chiloscyllium punctatum) embryos can detect predator-mimicking electric fields and respond by ceasing their respiratory gill movements. Despite being confined to the small space within the egg case, where they are vulnerable to predators, ...

  15. Reduction Of Power Line Humming And High Frequency Noise From Electrocardiogram Signals

    OpenAIRE

    Mohammed Nabil Abdalazim Mursi; Dr. Mohamed. H. M. Nerma

    2015-01-01

    ABSTRACT With the latest advancements in electronics several techniques are used for removal of unwanted entities from signals especially that are implied in the most complicated applications. The removal of power line interference from most sensitive medical monitoring equipments can also be achieved by implementing various useful techniques. The power line interference 5060 Hz is the main source of noise in most of bio-electric signals. The thesis report presents the removal of power line i...

  16. Low-voltage high CMRR OTA for electrophysiological measurements

    OpenAIRE

    Mitra, S.; Zele, R; Etienne-Cummings, R.

    2009-01-01

    With the advent of miniaturised sensors for various engineering and medical applications there is an increased demand of low-power, low-voltage analog building blocks like opamps and OTAs. Degradation of certain amplifier characteristics with supply voltage is a major concern for low-voltage design and often poses contradictory requirement. CMRR (common mode rejection ratio), one such feature, is essential for sensing small bio-electric signals riding over large common-mode voltage. Here we f...

  17. Impact of crystalline quality on neuronal affinity of pristine graphene

    OpenAIRE

    Veliev, Farida; Briançon-Marjollet, Anne; Bouchiat, Vincent; Delacour, Cécile

    2016-01-01

    International audience Due to its outstanding mechanical and electrical properties as well as chemical inertness, graphene has attracted a growing interest in the field of bioelectric interfacing. Herein, we investigate the suitability of pristine, i.e. without a cell adhesive coating, chemical vapor deposition (CVD) grown monolayer graphene to act as a platform for neuronal growth. We study the development of primary hippocampal neurons grown on bare graphene (transferred on glass coversl...

  18. Comparison of non-invasive electrohysterographic recording techniques for monitoring uterine dynamics

    OpenAIRE

    Alberola Rubio, José; Prats Boluda, Gema; Ye Lin, Yiyao; Valero, J; PERALES MARIN, ALFREDO JOSE; Garcia Casado, Francisco Javier

    2013-01-01

    Non-invasive recording of uterine myoelectric activity (electrohysterogram, EHG) could provide an alternative to monitoring uterine dynamics by systems based on tocodynamometer (TOCO). Laplacian recording of bioelectric signals has been shown to give better spatial resolution and less interference than mono and bipolar surface recordings. The aim of this work was to study the signal quality obtaines from monopolar, bipolar and Laplacian techniques in EHG recordings, as well as to assess their...

  19. Prediction of Treatment Outcome with Bioimpedance Measurements in Breast Cancer Related Lymphedema Patients

    OpenAIRE

    Kim, Leesuk; Jeon, Jae Yong; Sung, In Young; Jeong, Soon Yong; Do, Jung Hwa; Kim, Hwa Jung

    2011-01-01

    Objective To investigate the usefulness of bioimpedance measurement for predicting the treatment outcome in breast cancer related lymphedema (BCRL) patients. Method Unilateral BCRL patients who received complex decongestive therapy (CDT) for 2 weeks (5 days per week) were enrolled in this study. We measured the ratio of extracellular fluid (ECF) volume by using bioelectrical impedance spectroscopy (BIS), and single frequency bioimpedance analysis (SFBIA) at a 5 kHz frequency before treatment....

  20. A Global Model for Agriculture and Bioenergy: Application to Biofuel and Food Security in Peru and Tanzania

    OpenAIRE

    Elbehri, Aziz; McDougall, Robert; Horridge, Mark

    2009-01-01

    This paper describes a global model for agriculture and bioenergy (GLOMAB) that incorporates biomass, biofuels and bioelectricity sectors into the GTAP-Energy model by expanding the global GTAP database, production and consumption structures. Biofuels are separated between first- generation (sugar ethanol, starch ethanol) and second- generation (cellulosic ethanol) biofuels and associated biomass feedstocks (maize, sugar cane, crop residues, woody biomass). Beside biofuels, the model also inc...

  1. Food behavior, body image and anthropometric indices of university students
    Comportamento alimentar, imagem corporal e índices antropométricos de universitários

    OpenAIRE

    M. R. P. MONTEIRO; V. F. ZANIRATI; M. L. ANDRADE; R.R. Silva

    2010-01-01

    The aim of this study was to assess food behavior, self-image perception and anthropometric indices of college students. This was a cross-sectional study with 54 students in a public university. The lifestyle and self-image perception was collected using a standardized questionnaire tested. Food behavior was evaluated through the Eating Attitudes Test. Body composition was assessed for Body Mass Index (BMI), circumferences, skinfold analysis and bioelectrical impedan...

  2. FOOD BEHAVIOR, BODY IMAGE AND ANTHROPOMETRIC INDICES OF UNIVERSITY STUDENTS

    OpenAIRE

    Márcia Regina Pereira MONTEIRO; Viviane Ferreira ZANIRATI; Mariana Lage de Oliveira ANDRADE; Silva, Roberta Ribeiro

    2010-01-01

    The aim of this study was to assess food behavior, self-image perception and anthropometric indices of college students. This was a cross-sectional study with 54 students in a public university. The lifestyle and self-image perception was collected using a standardized questionnaire tested. Food behavior was evaluated through the Eating Attitudes Test. Body composition was assessed for Body Mass Index (BMI), circumferences, skinfold analysis and bioelectrical impedan...

  3. Dynamics of the component of body composition in athletes playing sports with damage to the medial meniscus of the knee

    OpenAIRE

    Moh'd Khalil Moh'd Abdel Kader.

    2012-01-01

    The question of the influence of the developed program of physical rehabilitation with the use of modern means and methods of recovery on the performance component of body composition in athletes playing sports after arthroscopic stapling the medial meniscus was considered. The analysis and synthesis of scientific and methodological data on the determination of body composition analysis techniques using bioelectrical resistance was shown. Found that long-term immobilization that accompanies t...

  4. Fast-Food Restaurant Advertising on Television and Its Influence on Youth Body Composition

    OpenAIRE

    Grossman, Michael; Tekin, Erdal; Wada, Roy

    2012-01-01

    We examine the effects of fast-food restaurant advertising on television on the body composition of adolescents as measured by percentage body fat (PBF) and to assess the sensitivity of these effects to using conventional measures of youth obesity based on body-mass index (BMI). We merge measures of body composition from bioelectrical-impedance analysis (BIA) and dual-energy x-ray absorptiometry (DXA) from the National Health and Nutrition Examination Survey with individual level data from th...

  5. Molecular ferroelectrics: where electronics meet biology

    OpenAIRE

    Li, Jiangyu; Liu, Yuanming; Zhang, Yanhang; Cai, Hong-Ling; Xiong, Ren-Gen

    2013-01-01

    In the last several years, we have witnessed significant advances in molecular ferroelectrics, with ferroelectric properties of molecular crystals approaching those of barium titanate. In addition, ferroelectricity has been observed in biological systems, filling an important missing link in bioelectric phenomena. In this perspective, we will present short historical notes on ferroelectrics, followed by overview on the fundamentals of ferroelectricity. Latest development in molecular ferroele...

  6. Food Prices and Body Fatness among Youths

    OpenAIRE

    Grossman, Michael; Tekin, Erdal; Wada, Roy

    2013-01-01

    In this paper, we examine the effect of food prices on clinical measures of obesity, including body mass index (BMI) and percentage body fat (PBF) measures derived from bioelectrical impedance analysis (BIA) and dual energy x-ray absorptiometry (DXA), among youths ages 12 through 18. The empirical analyses employ data from various waves of the National Health and Nutrition Examination Survey (NHANES) merged with several food prices measured by county and year. This is the first study to consi...

  7. Depolarization Alters Phenotype, Maintains Plasticity of Predifferentiated Mesenchymal Stem Cells

    OpenAIRE

    Sundelacruz, Sarah; Levin, Michael; Kaplan, David L

    2013-01-01

    Although adult stem cell transplantation has been implemented as a therapy for tissue repair, it is limited by the availability of functional adult stem cells. A potential approach to generate stem and progenitor cells may be to modulate the differentiated status of somatic cells. Therefore, there is a need for a better understanding of how the differentiated phenotype of mature cells is regulated. We hypothesize that bioelectric signaling plays an important role in the maintenance of the dif...

  8. Correction of Hypothyroidism Seems to Have No Effect on Body Fat

    OpenAIRE

    Okan Bakiner; Emre Bozkirli; Emine Duygu Ersozlu Bozkirli; Kursat Ozsahin

    2013-01-01

    Aim. We aimed to observe the effects of L-thyroxine replacement therapy on body fat content determined with various anthropometric methods and a bioelectrical impedance analysis method in patients with hypothyroidism. Methods. Forty-two women with naive autoimmune hypothyroidism were included. Also, 40 healthy participants were enrolled as a control group. Weight, body mass index, waist circumference, and subscapulary, suprailiac, femur, biceps, and triceps skin fold thicknesses were measured...

  9. Relationship between body composition and BMI in preschool children

    OpenAIRE

    Sakai, Toshiro; Demura, Shinichi; Fujii, Katsunori

    2012-01-01

    Childhood obesity is one of the most serious public health challenges of the 21st century. Obesity is a state in which body fat accumulates to an abnormal degree, and detailed information about body composition is necessary to investigate the problems of obesity in children. In the present study, we measured body composition using equipment based on the multifrequency bioelectrical impedance analysis method to measure lean body mass and the quantity of fat. We evaluated differences in body co...

  10. 主婦の体重コントロールに関する食事指導の研究(第6報) : 体脂肪パターンに及ぼす食事指導の効果

    OpenAIRE

    小西, 由起; 小西, すず; 鈴木, 秋子; 楠, 智一

    1999-01-01

    The purpose of this report was to examine the effects of our diet course on the body fat distribution of 93 housewives. Bioelectrical impedance analysis was performed for body fat measurement. After the execution of our advices concerning with daily food intake and positive exercise for 4 months, percentage body fat of the housewives decreased significantly in average. Furthermore, the statistical relation between total body fat - and body weight - reductions was confirmed. In addition, the r...

  11. The relationship between distribution of body fat mass and carotid artery intima-media thickness in Korean older adults

    OpenAIRE

    Park, Jin-Kee; Park, Hyuntae; Kim, Kwi-Baek

    2015-01-01

    [Purpose] The aim of this study was to examine the relationships between the amount and distribution of body fat and the carotid intima-media thickness to explore whether coronary artery disease risk may be mediated through effects on the amount of fat mass in older adults. [Subjects and Methods] A total of 200 elderly females was participated. The percentage of body fat mass was measured by the bioelectrical impedance analysis method, and the carotid intima-media thickness was measured by B-...

  12. OVERWEIGHT AND OBESITY RISK ASSESSMENT - TWO METHODS, DIFFERENT RESULTS

    OpenAIRE

    Pop Cristiana Lucretia

    2016-01-01

    Purpose : the purpose of this study was to verify if there is any significant difference between body fat assessment by calculating body mass index and by using bioelectrical impedance analysis. Materials: subsequently we determined the ratio between body fat and muscular mass percentage in a sample of 156 university girl students. Results : BMI and muscle mass percentage seem to have similar variance and trends, while body fat exceeded in numbers and percents the highest levels of BMI. While...

  13. Effect of artificial electric fields on plants grown under microgravity conditions

    Science.gov (United States)

    Nechitailo, G.; Gordeev, A.

    2001-01-01

    Ionic and structural hetorogeneity of cells, tissues, and organs of plants are associated with a spectrum of electric characteristics such as bioelectric potentials, electrical conductance, and bioelectric permeability. An important determinant for the plant function is electric properties of the cell membranes and organelles which maintain energy and substance exchange with the environment. Enzymes and other biologically active substances have a powerful charge at the molecular level. Finally, all molecules, including those of water, represent dipoles, and this determines their reactive capacity. A major determinant is the bioelectric polarity of a plant is genetically predetermined and cannot be modified. It is an intrinsic structural feature of the organism whose evolution advent was mediated by gravity. An illustrative presentation of polarity is the downward growth of the roots and upward growth of stems in the Earth's gravitation field. However, gravity is a critical, but not the sole determinant of the plant organism polarization. Potent polarizing effects are exerted by light, the electromagnetic field, moisture, and other factors. It is known that plant cultivation in an upturned position is associated with impairment of water and nutrient uptake, resulting in dyscoordination of physiological processes, growth and developmental retardation. These abnormalities were characteristic when early attempts were made to grow plants in weightlessness conditions.

  14. Anditalea andensis ANESC-ST--An Alkaliphilic Halotolerant Bacterium Capable of Electricity Generation under Alkaline-Saline Conditions.

    Directory of Open Access Journals (Sweden)

    Wei Shi

    Full Text Available A great challenge in wastewater bioremediation is the sustained activity of viable microorganisms, which can contribute to the breakdown of waste contaminants, especially in alkaline pH conditions. Identification of extremophiles with bioremediation capability can improve the efficiency of wastewater treatment. Here, we report the discovery of an electrochemically active alkaliphilic halotolerant bacterium, Anditalea andensis ANESC-ST (=CICC10485T=NCCB 100412T, which is capable of generating bioelectricity in alkaline-saline conditions. A. andensis ANESC-ST was shown to grow in alkaline conditions between pH 7.0-11.0 and also under high salt condition (up to 4 wt% NaCl. Electrical output was further demonstrated in microbial fuel cells (MFCs with an average current density of ~0.5 µA/cm2, even under the harsh condition of 4 wt% NaCl and pH 9.0. Subsequent introduction of secreted extracellular metabolites into MFCs inoculated with Escherichia coli or Pseudomonas aeruginosa yielded enhanced electrical output. The ability of A. andensis ANESC-ST to generate energy under alkaline-saline conditions points towards a solution for bioelectricity recovery from alkaline-saline wastewater. This is the first report of A.andensis ANESC-ST producing bioelectricity at high salt concentration and pH.

  15. DC feedback for wide band frequency fixed current source

    Directory of Open Access Journals (Sweden)

    Aoday Hashim Mohamad Al-Rawi

    2013-03-01

    Full Text Available Alternating current sources are mainly used in bioelectrical impedance devices. Nowadays 50 – 100 kHz bioelectrical impedance devices are commonly used for body composition analysis. High frequency bioelectrical impedance analysis devices are mostly used in bioimpedance tomography and blood analysis. High speed op-amps and voltage comparators are used in this circuit. Direct current feedback is used to prevent delay. An N-Channel J-FET transistor was used to establish the voltage controlled gain amplifier (VCG. A sine wave signal has been applied as input voltage. The value of this signal should be constant in 170 mV rms to keep the output current in about 1 mA rms. Four frequencies; 100 kHz, 1 MHz, 2 MHz and 3.2 MHz were applied to the circuit and the current was measured for different load resistances. The results showed that the current was stable for changes in the resistor load, bouncing around an average point as a result of bouncing DC feedback.

  16. An optical microfluidic platform for spatiotemporal biofilm treatment monitoring

    Science.gov (United States)

    Kim, Young Wook; Mosteller, Matthew P.; Subramanian, Sowmya; Meyer, Mariana T.; Bentley, William E.; Ghodssi, Reza

    2016-01-01

    Bacterial biofilms constitute in excess of 65% of clinical microbial infections, with the antibiotic treatment of biofilm infections posing a unique challenge due to their high antibiotic tolerance. Recent studies performed in our group have demonstrated that a bioelectric effect featuring low-intensity electric signals combined with antibiotics can significantly improve the efficacy of biofilm treatment. In this work, we demonstrate the bioelectric effect using sub-micron thick planar electrodes in a microfluidic device. This is critical in efforts to develop microsystems for clinical biofilm infection management, including both in vivo and in vitro applications. Adaptation of the method to the microscale, for example, can enable the development of localized biofilm infection treatment using microfabricated medical devices, while augmenting existing capabilities to perform biofilm management beyond the clinical realm. Furthermore, due to scale-down of the system, the voltage requirement for inducing the electric field is reduced further below the media electrolysis threshold. Enhanced biofilm treatment using the bioelectric effect in the developed microfluidic device elicited a 56% greater reduction in viable cell density and 26% further decrease in biomass growth compared to traditional antibiotic therapy. This biofilm treatment efficacy, demonstrated in a micro-scale device and utilizing biocompatible voltage ranges, encourages the use of this method for future clinical biofilm treatment applications.

  17. CONSTRUCTION OF DOUBLE CHAMBERED MICROBIAL FUEL CELL (MFC USING HOUSEHOLD MATERIALS AND BACILLUS MEGATERIUM ISOLATE FROM TEA GARDEN SOIL

    Directory of Open Access Journals (Sweden)

    Debajit Borah

    2013-08-01

    Full Text Available The current study was carried out for the isolation and screening of potential bioelectricity generating bacteria from tea garden soil samples and also to construct an indigenous microbial fuel cell (MFC using house hold materials. Bacillus megaterium was found to the best isolate for the production of bioelectricity, out of a total of 25 bacterial isolates from soil samples of Lepetkata Tea Estate of Dibrugarh district of Assam. The isolate was identified on the basis of staining techniques and biochemical characteristics. Double chambered MFC was constructed by using two poly acrylic containers of 500 ml volume each. The two chambers were connected using an agar salt bridge and carbon rods were used as electrodes. The electricity generated by the isolate was compared using glucose and fructose as sole carbon source in minimal media. The maximum voltage was found to be 440 mV in presence of glucose as sole carbon source after 84 hrs of incubation at room temperature. The voltage was further increased up to 698 mV after the media was supplemented with 1.5 % (w/v yeast extract, which would have served as additional source of vitamin to the bacteria to proliferate. During the entire study, the experimental set up was allowed to incubate at room temperature and occasional shaking was done manually, hence no external electricity was required. With all the above features the isolate Bacillus megaterium was found to be a good source of bioelectricity.

  18. Transmembrane voltage potential of somatic cells controls oncogene-mediated tumorigenesis at long-range.

    Science.gov (United States)

    Chernet, Brook T; Levin, Michael

    2014-05-30

    The microenvironment is increasingly recognized as a crucial aspect of cancer. In contrast and complement to the field's focus on biochemical factors and extracellular matrix, we characterize a novel aspect of host:tumor interaction - endogenous bioelectric signals among non-excitable somatic cells. Extending prior work focused on the bioelectric state of cancer cells themselves, we show for the first time that the resting potentials of distant cells are critical for oncogene-dependent tumorigenesis. In the Xenopus laevis tadpole model, we used human oncogenes such as mutant KRAS to drive formation of tumor-like structures that exhibited overproliferation, increased nuclear size, hypoxia, acidity, and leukocyte attraction. Remarkably, misexpression of hyperpolarizing ion channels at distant sites within the tadpole significantly reduced the incidence of these tumors. The suppression of tumorigenesis could also be achieved by hyperpolarization using native CLIC1 chloride channels, suggesting a treatment modality not requiring gene therapy. Using a dominant negative approach, we implicate HDAC1 as the mechanism by which resting potential changes affect downstream cell behaviors. Based on published data on the voltage-mediated changes of butyrate flux through the SLC5A8 transporter, we present a model linking resting potentials of host cells to the ability of oncogenes to initiate tumorigenesis. Antibiotic data suggest that the relevant butyrate is generated by a native bacterial species, identifying a novel link between the microbiome and cancer that is mediated by alterations in bioelectric signaling. PMID:24830454

  19. Nutritional assessment in patients with cirrhosis

    Directory of Open Access Journals (Sweden)

    Sabrina Alves Fernandes

    2012-03-01

    Full Text Available CONTEXT: Malnutrition in cirrhotic patients with end-stage disease is common, and the degree of nutritional debilitation can play an important role in the pathogenesis of complications and cause a negative impact on prognosis. However, it involves difficulties and controversies regarding the identification of the best nutritional assessment method. OBJECTIVE: To identify a method that provides a safe and effective nutritional diagnosis. METHODS: Cross-sectional study with 129 cirrhotic patients. Anthropometric measurements, subjective global assessment, hand grip strength and bioelectrical impedance. RESULTS: Through phase angle of bioelectrical impedance analysis (BIA method, significant associations with Child-Pugh (P = 0.008, age group and gender were observed. The ROC (receiver operator characteristic curve was generated to determine the best cutoff point of the phase angle of cirrhotic patients, serving as one of the reference parameters for the nutritional assessment with bioimpedance in this study, considering the classification through Child-Pugh score as the reference standard for the clinical conditions of patients with cirrhosis. CONCLUSIONS: The assessment through bioelectrical impedance presented a statistically significant correlation with Child-Pugh score. The identification of phase angle of 5.44º is the new parameter suggested for the classification of the nutritional conditions of cirrhotic patients.

  20. Anditalea andensis ANESC-ST - An Alkaliphilic Halotolerant Bacterium Capable of Electricity Generation under Alkaline-Saline Conditions

    Science.gov (United States)

    Shi, Wei; Wang, Victor Bochuan; Zhao, Cui-E; Zhang, Qichun; Loo, Say Chye Joachim; Yang, Liang; Xu, Chenjie

    2015-01-01

    A great challenge in wastewater bioremediation is the sustained activity of viable microorganisms, which can contribute to the breakdown of waste contaminants, especially in alkaline pH conditions. Identification of extremophiles with bioremediation capability can improve the efficiency of wastewater treatment. Here, we report the discovery of an electrochemically active alkaliphilic halotolerant bacterium, Anditalea andensis ANESC-ST (=CICC10485T=NCCB 100412T), which is capable of generating bioelectricity in alkaline–saline conditions. A. andensis ANESC-ST was shown to grow in alkaline conditions between pH 7.0–11.0 and also under high salt condition (up to 4 wt% NaCl). Electrical output was further demonstrated in microbial fuel cells (MFCs) with an average current density of ~0.5 µA/cm2, even under the harsh condition of 4 wt% NaCl and pH 9.0. Subsequent introduction of secreted extracellular metabolites into MFCs inoculated with Escherichia coli or Pseudomonas aeruginosa yielded enhanced electrical output. The ability of A. andensis ANESC-ST to generate energy under alkaline–saline conditions points towards a solution for bioelectricity recovery from alkaline–saline wastewater. This is the first report of A.andensis ANESC-ST producing bioelectricity at high salt concentration and pH. PMID:26171779

  1. Anditalea andensis ANESC-ST--An Alkaliphilic Halotolerant Bacterium Capable of Electricity Generation under Alkaline-Saline Conditions.

    Science.gov (United States)

    Shi, Wei; Wang, Victor Bochuan; Zhao, Cui-E; Zhang, Qichun; Loo, Say Chye Joachim; Yang, Liang; Xu, Chenjie

    2015-01-01

    A great challenge in wastewater bioremediation is the sustained activity of viable microorganisms, which can contribute to the breakdown of waste contaminants, especially in alkaline pH conditions. Identification of extremophiles with bioremediation capability can improve the efficiency of wastewater treatment. Here, we report the discovery of an electrochemically active alkaliphilic halotolerant bacterium, Anditalea andensis ANESC-ST (=CICC10485T=NCCB 100412T), which is capable of generating bioelectricity in alkaline-saline conditions. A. andensis ANESC-ST was shown to grow in alkaline conditions between pH 7.0-11.0 and also under high salt condition (up to 4 wt% NaCl). Electrical output was further demonstrated in microbial fuel cells (MFCs) with an average current density of ~0.5 µA/cm2, even under the harsh condition of 4 wt% NaCl and pH 9.0. Subsequent introduction of secreted extracellular metabolites into MFCs inoculated with Escherichia coli or Pseudomonas aeruginosa yielded enhanced electrical output. The ability of A. andensis ANESC-ST to generate energy under alkaline-saline conditions points towards a solution for bioelectricity recovery from alkaline-saline wastewater. This is the first report of A.andensis ANESC-ST producing bioelectricity at high salt concentration and pH. PMID:26171779

  2. Optogenetics in Developmental Biology: using light to control ion flux-dependent signals in Xenopus embryos.

    Science.gov (United States)

    Spencer Adams, Dany; Lemire, Joan M; Kramer, Richard H; Levin, Michael

    2014-01-01

    Developmental bioelectricity, electrical signaling among non-excitable cells, is now known to regulate proliferation, apoptosis, gene expression, and patterning during development. The extraordinary temporal and spatial resolution offered by optogenetics could revolutionize the study of bioelectricity the same way it has revolutionized neuroscience. There is, however, no guide to adapting optogenetics to patterning systems. To fill this gap, we used optogenetic reagents, both proteins and photochemical switches, to vary steady-state bioelectrical properties of non-spiking embryonic cells in Xenopus laevis. We injected mRNA for various proteins, including Channelrhodopsins and Archaerhodopsin, into 1-8 cell embryos, or soaked embryos in media containing photochemical switches, then examined the effect of light and dark on membrane voltage (Vmem) using both electrodes and fluorescent membrane voltage reporters. We also scored tadpoles for known effects of varying Vmem, including left-right asymmetry disruption, hyperpigmentation, and craniofacial phenotypes. The majority of reagents we tested caused a significant increase in the percentage of light-exposed tadpoles showing relevant phenotypes; however, the majority of reagents also induced phenotypes in controls kept in the dark. Experiments on this "dark phenotype" yielded evidence that the direction of ion flux via common optogenetic reagents may be reversed, or unpredictable in non-neural cells. When used in combination with rigorous controls, optogenetics can be a powerful tool for investigating ion-flux based signaling in non-excitable systems. Nonetheless, it is crucial that new reagents be designed with these non-neural cell types in mind.

  3. Reduction of F1 Neuronal Excitability by Exposure to 217 Hz Magnetic Fields from GSM 900 Mobile Phone

    Directory of Open Access Journals (Sweden)

    Mehri Kaviani Moghadam

    2009-01-01

    Full Text Available Objective: The aim of this study was to investigate the effects of a 217 Hz magnetic field ofmobile phone GSM 900 exposure on the bioelectric activity of F1 neuronal cells of the landsnail.Materials and Methods: According to the magnetic field measurement of the mobile phone,a range of flux intensities of magnetic fields (0.46 - 229 μT at a frequency of 217 Hz wasproduced by magnetic field coils. The bioelectrical activity of F1 nerve cells at different timeintervals was recorded, using intracellular recording under current clamp conditions in control,sham and field exposed groups.Results: Magnetic field exposure decreased the amplitude of action potential and the firingfrequency of F1 nerve cells. Furthermore, it resulted in a significant (p<0.05 increase inthe amplitude of after hyperpolarization (AHP and duration of action potential. Change inthe cell’s electrophysiological parameters was associated with a decrease in neuronal excitability.Magnetic field exposure affected also the resting membrane potential of F1 cells in abimodal fashion, including depolarization and hyperpolarization. Considering the exposurecondition, most of the alterations in the electrical activity of F1 nerve cells induced by magneticfields exposure were reversible.Conclusion: These findings suggest that 217 Hz magnetic fields of mobile phones with differentintensities affect the spontaneous bioelectrical activity of F1 nerve cells and exert inhibitoryeffects on neuronal excitability. There is evidence for the existence of an amplitudewindow and these electrophysiological alterations occur within this amplitude window. Thereversibility of the magnetic field- induced most electrophysiological alterations in the neuronalbehavior under our experimental conditions was observed.

  4. Long-range gap junctional signaling controls oncogene-mediated tumorigenesis in Xenopus laevis embryos

    Directory of Open Access Journals (Sweden)

    Brook T Chernet

    2015-01-01

    Full Text Available In addition to the immediate microenvironment, long-range signaling may be an important component of cancer. Molecular-genetic analyses have implicated gap junctions – key mediators of cell-cell communication – in carcinogenesis. We recently showed that the resting voltage potential of distant cell groups is a key determinant of metastatic transformation and tumor induction. Here, we show in the Xenopus laevis model that gap junctional communication (GJC is a modulator of the long-range bioelectric signaling that regulates tumor formation. Genetic disruption of GJC taking place within tumors, within remote host tissues, or between the host and tumors – significantly lowers the incidence of tumors induced by KRAS mutations. The most pronounced suppression of tumor incidence was observed upon GJC disruption taking place farther away from oncogene-expressing cells, revealing a role for GJC in distant cells in the control of tumor growth. In contrast, enhanced GJC communication through the overexpression of wild-type connexin Cx26 increased tumor incidence. Our data confirm a role for GJC in tumorigenesis, and reveal that this effect is non-local. Based on these results and on published data on movement of ions through GJs, we present a quantitative model linking the GJC coupling and bioelectrical state of cells to the ability of oncogenes to initiate tumorigenesis. When integrated with data on endogenous bioelectric signaling during left-right patterning, the model predicts differential tumor incidence outcomes depending on the spatial configurations of gap junction paths relative to tumor location and major anatomical body axes. Testing these predictions, we found that the strongest influence of GJ modulation on tumor suppression by hyperpolarization occurred along the embryonic left-right axis. Together, these data reveal new, long-range aspects of cancer control by the host’s physiological parameters.

  5. Long-range gap junctional signaling controls oncogene-mediated tumorigenesis in Xenopus laevis embryos.

    Science.gov (United States)

    Chernet, Brook T; Fields, Chris; Levin, Michael

    2014-01-01

    In addition to the immediate microenvironment, long-range signaling may be an important component of cancer. Molecular-genetic analyses have implicated gap junctions-key mediators of cell-cell communication-in carcinogenesis. We recently showed that the resting voltage potential of distant cell groups is a key determinant of metastatic transformation and tumor induction. Here, we show in the Xenopus laevis model that gap junctional communication (GJC) is a modulator of the long-range bioelectric signaling that regulates tumor formation. Genetic disruption of GJC taking place within tumors, within remote host tissues, or between the host and tumors significantly lowers the incidence of tumors induced by KRAS mutations. The most pronounced suppression of tumor incidence was observed upon GJC disruption taking place farther away from oncogene-expressing cells, revealing a role for GJC in distant cells in the control of tumor growth. In contrast, enhanced GJC communication through the overexpression of wild-type connexin Cx26 increased tumor incidence. Our data confirm a role for GJC in tumorigenesis, and reveal that this effect is non-local. Based on these results and on published data on movement of ions through GJs, we present a quantitative model linking the GJC coupling and bioelectrical state of cells to the ability of oncogenes to initiate tumorigenesis. When integrated with data on endogenous bioelectric signaling during left-right patterning, the model predicts differential tumor incidence outcomes depending on the spatial configurations of gap junction paths relative to tumor location and major anatomical body axes. Testing these predictions, we found that the strongest influence of GJ modulation on tumor suppression by hyperpolarization occurred along the embryonic left-right axis. Together, these data reveal new, long-range aspects of cancer control by the host's physiological parameters. PMID:25646081

  6. Long-range gap junctional signaling controls oncogene-mediated tumorigenesis in Xenopus laevis embryos

    Science.gov (United States)

    Chernet, Brook T.; Fields, Chris; Levin, Michael

    2015-01-01

    In addition to the immediate microenvironment, long-range signaling may be an important component of cancer. Molecular-genetic analyses have implicated gap junctions—key mediators of cell-cell communication—in carcinogenesis. We recently showed that the resting voltage potential of distant cell groups is a key determinant of metastatic transformation and tumor induction. Here, we show in the Xenopus laevis model that gap junctional communication (GJC) is a modulator of the long-range bioelectric signaling that regulates tumor formation. Genetic disruption of GJC taking place within tumors, within remote host tissues, or between the host and tumors significantly lowers the incidence of tumors induced by KRAS mutations. The most pronounced suppression of tumor incidence was observed upon GJC disruption taking place farther away from oncogene-expressing cells, revealing a role for GJC in distant cells in the control of tumor growth. In contrast, enhanced GJC communication through the overexpression of wild-type connexin Cx26 increased tumor incidence. Our data confirm a role for GJC in tumorigenesis, and reveal that this effect is non-local. Based on these results and on published data on movement of ions through GJs, we present a quantitative model linking the GJC coupling and bioelectrical state of cells to the ability of oncogenes to initiate tumorigenesis. When integrated with data on endogenous bioelectric signaling during left-right patterning, the model predicts differential tumor incidence outcomes depending on the spatial configurations of gap junction paths relative to tumor location and major anatomical body axes. Testing these predictions, we found that the strongest influence of GJ modulation on tumor suppression by hyperpolarization occurred along the embryonic left-right axis. Together, these data reveal new, long-range aspects of cancer control by the host's physiological parameters. PMID:25646081

  7. Transmembrane voltage potential is an essential cellular parameter for the detection and control of tumor development in a Xenopus model.

    Science.gov (United States)

    Chernet, Brook T; Levin, Michael

    2013-05-01

    Understanding mechanisms that orchestrate cell behavior into appropriately patterned tissues and organs within the organism is an essential element of preventing, detecting and treating cancer. Bioelectric signals (resting transmembrane voltage potential gradients in all cells) underlie an important and broadly conserved set of control mechanisms that regulate pattern formation. We tested the role of transmembrane potential in tumorigenesis mediated by canonical oncogenes in Xenopus laevis. Depolarized membrane potential (Vmem) was a characteristic of induced tumor-like structures (ITLSs) generated by overexpression of Gli1, Kras(G12D), Xrel3 or p53(Trp248). This bioelectric signature was also present in precursor ITLS sites. Vmem is a bioelectric marker that reveals ITLSs before they become histologically and morphologically apparent. Moreover, voltage was functionally important: overexpression of hyperpolarizing ion transporters caused a return to normal Vmem and significantly reduced ITLS formation in vivo. To characterize the molecular mechanism by which Vmem change regulates ITLS phenotypes, we performed a suppression screen. Vmem hyperpolarization was transduced into downstream events via Vmem-regulated activity of SLC5A8, a sodium-butyrate exchanger previously implicated in human cancer. These data indicate that butyrate, a histone deacetylase (HDAC) inhibitor, might be responsible for transcriptional events that mediate suppression of ITLSs by hyperpolarization. Vmem is a convenient cellular parameter by which tumors induced by human oncogenes can be detected in vivo and represents a new diagnostic modality. Moreover, control of resting membrane potential is functionally involved in the process by which oncogene-bearing cells depart from normal morphogenesis programs to form tumors. Modulation of Vmem levels is a novel and promising strategy for tumor normalization. PMID:23471912

  8. Gap Junctional Blockade Stochastically Induces Different Species-Specific Head Anatomies in Genetically Wild-Type Girardia dorotocephala Flatworms

    Directory of Open Access Journals (Sweden)

    Maya Emmons-Bell

    2015-11-01

    Full Text Available The shape of an animal body plan is constructed from protein components encoded by the genome. However, bioelectric networks composed of many cell types have their own intrinsic dynamics, and can drive distinct morphological outcomes during embryogenesis and regeneration. Planarian flatworms are a popular system for exploring body plan patterning due to their regenerative capacity, but despite considerable molecular information regarding stem cell differentiation and basic axial patterning, very little is known about how distinct head shapes are produced. Here, we show that after decapitation in G. dorotocephala, a transient perturbation of physiological connectivity among cells (using the gap junction blocker octanol can result in regenerated heads with quite different shapes, stochastically matching other known species of planaria (S. mediterranea, D. japonica, and P. felina. We use morphometric analysis to quantify the ability of physiological network perturbations to induce different species-specific head shapes from the same genome. Moreover, we present a computational agent-based model of cell and physical dynamics during regeneration that quantitatively reproduces the observed shape changes. Morphological alterations induced in a genomically wild-type G. dorotocephala during regeneration include not only the shape of the head but also the morphology of the brain, the characteristic distribution of adult stem cells (neoblasts, and the bioelectric gradients of resting potential within the anterior tissues. Interestingly, the shape change is not permanent; after regeneration is complete, intact animals remodel back to G. dorotocephala-appropriate head shape within several weeks in a secondary phase of remodeling following initial complete regeneration. We present a conceptual model to guide future work to delineate the molecular mechanisms by which bioelectric networks stochastically select among a small set of discrete head morphologies

  9. Greenhouse gas mitigation potential of a second generation energy production system from short rotation poplar in Eastern Germany and its accompanied uncertainties

    International Nuclear Information System (INIS)

    This study investigates the variance of the overall greenhouse gas mitigation potential of a complete second generation stationary bio-electricity production system, generated by poplar wood chips (Populus spec.) in Germany, using Monte Carlo simulations. We computed the GHG emissions as EB = (−0.034 ± 0.021) kg CO2e MJ−1 (mean ± SD) and the mitigation factor as MFB = (0.274 ± 0.021) kg CO2e MJ−1 following a life cycle assessment-based approach. Additionally, avoided nitrous oxide (N2O) emissions due to land use change were considered in the assessment. The most important factor for the overall mitigation variability was the uncertainty of the organic carbon changes in the soil, followed by the variability of yields. The uncertainty of (i) direct N2O emissions from the poplar site or (ii) the reference rye site as well as (iii) the uncertainty of heat recovery percentage was of minor importance. Uncertainties in the global warming potentials of nitrous oxide and methane and in the transport distance were found to be irrelevant. The uncertainty of the GHG mitigation which was associated with this specific electricity generation by poplar wood chips gasification was significantly lower compared to the variability of another common bio-electricity system (biogas). Uncertainty implications seem to be system-specific and therefore should be analysed separately for each bioenergy pathway under consideration. -- Highlights: •0.274 ± 0.021 kg CO2e mitigation MJ−1 from poplar wood chips gasification. •Variability of soil organic carbon was most important for the mitigation uncertainty. •Overall variability was lower compared to the variability of bio-electricity from biogas. •Bioenergy systems should be analysed separately regarding their uncertainty aspects

  10. Establishment of a beagle dog model of oculomotor nerve injury

    Institute of Scientific and Technical Information of China (English)

    Wenxiang Zhong; Xuhui Wang; Wenchuan Zhang; Shiting Li; Min Yang

    2011-01-01

    The oculomotor nerves of beagle dogs received electrical stimulation at 0.3-2.0 V. After recording compound muscle action potentials of the inferior oblique muscle, the oculomotor nerve was quickly cut off and a direct end-to-end anastomosis was then performed. As a result, the stimulating elec-trode was smoothly inserted and placed, and ideal bioelectrical signals of the interior oblique muscle were acquired. After oculomotor nerve injury, compound muscle action potentials of the inferior oblique muscle were significantly decreased in beagle dogs. These findings suggest that an animal model of oculomotor nerve injury was successfully established for electrophysiological studies.

  11. Comparing the accuracy of ES-BC, EIS-GS, and ES Oxi on body composition, autonomic nervous system activity, and cardiac output to standardized assessments

    OpenAIRE

    Lewis JE; Tannenbaum SL; Gao J; Melillo AB; Long EG; Alonso Y; Konefal J; Woolger JM; Leonard S; Singh PK; Chen L; Tiozzo E

    2011-01-01

    John E Lewis1, Stacey L Tannenbaum1, Jinrun Gao3, Angelica B Melillo1, Evan G Long1, Yaima Alonso2, Janet Konefal1, Judi M Woolger2, Susanna Leonard1, Prabjot K Singh1, Lawrence Chen1, Eduard Tiozzo1 1Department of Psychiatry and Behavioral Sciences, 2Department of Medicine, University of Miami Miller School of Medicine, Miami, FL, 3State Farm Insurance, Bloomington, IL, USA Background and purpose: The Electro Sensor Complex (ESC) is software that combines three devices using bioelectrical i...

  12. Principles of Biomedical Engineering

    CERN Document Server

    Madihally, Sundararajan V

    2010-01-01

    Describing the role of engineering in medicine today, this comprehensive volume covers a wide range of the most important topics in this burgeoning field. Supported with over 145 illustrations, the book discusses bioelectrical systems, mechanical analysis of biological tissues and organs, biomaterial selection, compartmental modeling, and biomedical instrumentation. Moreover, you find a thorough treatment of the concept of using living cells in various therapeutics and diagnostics.Structured as a complete text for students with some engineering background, the book also makes a valuable refere

  13. Body water distribution and risk of cardiovascular morbidity and mortality in a healthy population: a prospective cohort study.

    Directory of Open Access Journals (Sweden)

    Nikoline Nygård Knudsen

    Full Text Available BACKGROUND: Early alterations in the cardiovascular structure and function may change normal body water distribution. The resulting fluid shifts may thus serve as an early marker for cardiovascular disease. However, studies examining this in healthy populations are absent. OBJECTIVE: This study examined the association between the proportion of total body water that is extracellular water and subsequent development of non-fatal or fatal cardiovascular disease in a healthy population. METHOD: Bioelectrical impedance spectroscopy is an easy-to-use, non-invasive and relatively inexpensive technique to evaluate changes in body water distribution. A random subset (n = 2120 of Danes aged 41-71 years, examined in 1993-1994 for body water distribution by bioelectrical impedance spectroscopy was included. Cox-proportional hazard models and linear splines were performed. The ratio between resistance estimates from an infinite-frequency and from no-frequency (R∞/R0 was used as a surrogate measure of ratio between extracellular water and total body water. The outcome was 13.5 years of follow-up for cardiovascular morbidity and mortality. RESULTS: A high proportion of total body water that is extracellular water was associated with increased risk of incident cardiovascular disease. A threshold effect was evident, with greatly increased risk of cardiovascular morbidity and mortality above R∞/R0 = 0.68. Below the threshold there seemed to be no additional benefit of having a low ratio. CONCLUSION: Our findings suggest that non-clinically evident oedema, measured as an increased proportion of total body water that is extracellular, above a threshold of 0.68, may be an early marker of pre-clinical cardiovascular disease. This simple, safe, cheap and easily obtainable measure of R∞/R0 from bioelectrical impedance may help the early identification of these otherwise clinically healthy individuals who are at an increased risk of future cardiovascular disease

  14. Molecular ferroelectrics: where electronics meet biology.

    Science.gov (United States)

    Li, Jiangyu; Liu, Yuanming; Zhang, Yanhang; Cai, Hong-Ling; Xiong, Ren-Gen

    2013-12-28

    In the last several years, we have witnessed significant advances in molecular ferroelectrics, with the ferroelectric properties of molecular crystals approaching those of barium titanate. In addition, ferroelectricity has been observed in biological systems, filling an important missing link in bioelectric phenomena. In this perspective, we will present short historical notes on ferroelectrics, followed by an overview of the fundamentals of ferroelectricity. The latest developments in molecular ferroelectrics and biological ferroelectricity will then be highlighted, and their implications and potential applications will be discussed. We close by noting molecular ferroelectric as an exciting frontier between electronics and biology, and a number of challenges ahead are also described.

  15. Validity of dual X-ray absorptiometry scanning for determination of body composition in IDDM patients

    DEFF Research Database (Denmark)

    Rosenfalck, A M; Almdal, T; Gotfredsen, A;

    1995-01-01

    Data on body composition in patients with insulin-dependent diabetes mellitus (IDDM) are scarce. Dual X-ray absorptiometry (DXA) scanning has proved useful for this purpose in other groups of patients. We tested the validity of the DXA scanner for the determination of fat-free mass (FFM) and fat...... mass in IDDM patients and control subjects, as compared to other reference methods, i.e. total body potassium by 40K whole body counting (TBK), total body water by tritiated water (TBW), bioelectrical impedance analysis (BIA) and 24-h urinary creatinine excretion (Ucrea). A total of 13 healthy controls...

  16. Extracellular Electron Transfer Mediated by Flavins in Gram-positive Bacillus sp. WS-XY1 and Yeast Pichia stipitis

    International Nuclear Information System (INIS)

    Extracellular electron transfer (EET) of microorganisms represents a communicative bridge between the interior and exterior of the cells. Most prior EET studies have focused on Gram-negative bacteria. However, fungi and Gram-positive bacteria, that contain dense cellular walls, have rarely been reported. Herein, two model dense cell wall microorganisms (Bacillus sp. WS-XY1 and the yeast Pichia stipitis) were identified to be electrochemically active. Further analysis indicated that the two microorganisms were able to secrete flavins to mediate their EET. The discovery, that dense cell wall containing microorganisms can undertake mediated EET, adds to the body of knowledge towards building a comprehensive understanding of biogeochemical and bioelectrical processes

  17. Effects of antiepileptic drugs in electrophysiological tests.

    Science.gov (United States)

    Rump, S; Kowalczyk, M

    1987-01-01

    Methods of the study of antiepileptic drugs activity by means of analysis of their effects on bioelectrical ictal phenomena in the animal brain are described. The paper deals especially with EEG signal processing methods. Application of various nonparametric models (e.g. interval-amplitude scatter plots, power spectra analysis) as well as parametric models (e.g. autoregressive model, segmentation analysis) is discussed. A discriminative approach to some of these methods (especially to autoregressive model) is also presented. Special attention is stressed on the value of these methods for the study of anticonvulsant drugs activity.

  18. Influence of maturation on anthropometry and body composition in Japanese junior high school students

    OpenAIRE

    Fukunaga, Yuko; Takai, Yohei; Yoshimoto, Takaya; Fujita, Eiji; Yamamoto, Masayoshi; Kanehisa, Hiroaki

    2013-01-01

    Background The purpose of this study was to examine maturity-related differences in anthropometry and body composition in Japanese youth within a single year. Methods Two hundred and ten Japanese youth aged from 13 to 13.99 years participated in this study. Their maturity status was assessed using a self-assessment of stage of pubic hair development. Bioelectrical impedance analysis was used to estimate percent body fat and lean body mass (LBM). Muscle thickness of the anterior thigh, posteri...

  19. Design of Adaptive Filter Using Jordan/Elman Neural Network in a Typical EMG Signal Noise Removal

    Directory of Open Access Journals (Sweden)

    V. R. Mankar

    2009-01-01

    Full Text Available The bioelectric potentials associated with muscle activity constitute the electromyogram (EMG. These EMG signals are low-frequency and lower-magnitude signals. In this paper, it is presented that Jordan/Elman neural network can be effectively used for EMG signal noise removal, which is a typical nonlinear multivariable regression problem, as compared with other types of neural networks. Different neural network (NN models with varying parameters were considered for the design of adaptive neural-network-based filter which is a typical SISO system. The performance parameters, that is, MSE, correlation coefficient, N/P, and t, are found to be in the expected range of values.

  20. Body composition in detoxified alcoholics.

    Science.gov (United States)

    York, J L; Pendergast, D E

    1990-04-01

    Body composition was evaluated in healthy detoxified alcoholics (aged 20-39) and lifestyle controls, with the expectation that prolonged, excessive consumption of alcohol may bring about nutritional or toxicologic alterations in the relationship between body fat and lean body mass. Body fat was assessed by measurements of skin-fold thickness and by means of bioelectric impedance methodology. No noteworthy differences were observed between alcoholics and controls with regard to the relationship between lean body mass and body fat or in the relationship between extracellular and intracellular water. It would appear that 15-20 years of heavy alcohol consumption does not necessarily alter body composition in healthy, young alcoholics. PMID:2190482

  1. Education and training in medical physics in India

    International Nuclear Information System (INIS)

    Medical Physics is an applied branch of physics that deals with the application of physical principles, concepts and methods to the diagnosis and treatment of diseases. A medical physicist is involved in physics of imaging, quality assurance of radiological equipment, administration of radiation protection, radiobiological modeling, biomedical instrumentation, bioelectrical investigations of brain and heart, thermography, ultrasound, laser and nuclear magnetic resonance techniques. This presentation emphasises the need for adequately trained manpower to achieve the desired clinical objectives of the diagnosis and treatment in the cancer management programme of the institution

  2. Imaging the electric field associated with mouse and human skin wounds

    OpenAIRE

    Nuccitelli, Richard; Nuccitelli, Pamela; Ramlatchan, Samdeo; Sanger, Richard; Smith, Peter J.S.

    2008-01-01

    We have developed a noninvasive instrument called the bioelectric field imager (BFI) for mapping the electric field between the epidermis and the stratum corneum near wounds in both mouse and human skin. Rather than touching the skin, the BFI vibrates a small metal probe with a displacement of 180 μm in air above the skin to detect the surface potential of the epidermis through capacitative coupling. Here we describe our first application of the BFI measuring the electric field between the st...

  3. The Electrogenic Bacterium Shewanella Oneidensis MR-1 and its Mutants with Increased Reducing Capacity

    Science.gov (United States)

    Voeikova, T. A.; Emelyanova, L. K.; Novikova, L. M.; Mordkovich, N. N.; Shakulov, R. S.; Debabov, V. G.

    2013-02-01

    Mutants of Shewanella oneidensis MR-1 resistant to fosfomycin, a toxic analogue of phosphoenolpyruvate, were obtained. The mutants exhibited an increased reducing activity and a higher rate of lactate utilization. A correlation was shown between the rates of metabolism of oxidized substrates and the rate of reduction of methylene blue, a mediator of electron transport. The mutants of S.oneidensis MR-1 will be used in microbial fuel cells (MFC) to enhance energy production from organic compounds. The strain S. oneidensis MR-1 and its mutants with an increased electron production will be used as a good source of bioelectricity in MFC in the experiments on the International Space Station.

  4. A system for automated quantification of cutaneous electrogastrograms

    DEFF Research Database (Denmark)

    Paskaranandavadivel, Niranchan; Bull, Simon Henry; Parsell, Doug;

    2015-01-01

    recordings from the gastric mucosa and serosa in a reliable and efficient manner. In particular, the frequency and amplitude of the gastric slow waves were computed, after which signal integrity checks were performed to assess if the signals are valid. For validation, manual estimates of the frequency...... and amplitude were compared to automated estimates. The methods were packaged into a software executable which processes the data and presents the results in an intuitive graphical and a spreadsheet formats. Automated EGG analysis allows for clinical translation of bio-electrical analysis for potential...

  5. Adopt Various Teaching Methods: Giving Lessons on the Basic Function of Cell Based on Teaching of Sodium Potassium Pump%采用多种教学法——以钠钾泵为主线讲好细胞基本功能的体会

    Institute of Scientific and Technical Information of China (English)

    唐云; 张燕辉

    2012-01-01

    When giving lessons on the basic function of physiology cells, the author teaches complex and abstract bioelectric phenomenon based on sodium potassium pump by using various teaching methods like using multi-media courseware.%在生理学细胞的基本功能这一章节的授课中,以钠钾泵为主线,采用演示动态多媒体课件为主的多种教学手段,将抽象、复杂的细胞生物电现象,讲得比较透彻和直观.

  6. Dosimetry, instrumentation and exposure chambers for dc magnetic field studies

    Energy Technology Data Exchange (ETDEWEB)

    Tenforde, T.S.

    1979-03-01

    The principal objective of this report is to describe in detail an exposure chamber that was developed at the Lawrence Berkeley Laboratory for automated, noninvasive studies of rodent physiology during exposure to high DC magnetic fields. A second objective is to discuss some of the unique instrumentation problems that must be overcome in order to record bioelectric signals from laboratory animals in the presence of a magnetic field. Finally, a description will be given of the various dosimetry techniques that can be employed for quantitation of magnetic field strength.

  7. Pentachlorophenol Degradation in an Anaerobic System with Bioelectrochemical Catalysis%五氯酚的生物电化学催化厌氧转化过程与机制

    Institute of Scientific and Technical Information of China (English)

    曹占平; 张景丽; 张宏伟

    2013-01-01

    研究了电催化体系、厌氧微生物体系和厌氧微生物电化学催化体系(电生物体系)对五氯酚(PCP)的降解,研究发现电生物体系的降解效率较电催化体系提高85.2%,较微生物体系提高18.5%.电生物体系中PCP脱氯的途径为:PCP先间位脱氯主要生成2,3,4,6-TeCP和2,4,6-TCP,而后2,4,6-TCP脱氯主要生成2,4-DCP,再经对位脱氯生成邻氯酚和苯酚;苯酚在阳极附近多菌种协同作用下进一步氧化,从而减少苯酚的积累加快了PCP的还原转化.电生物体系通过微生物对电子的“长”距离传递和生物还原转化,形成了电化学与生物的交互反应过程,提高了PCP的降解效果.%The pentachlorophenol ( PCP) degradation using an electrocatalytic system, an anaerobic system, and an anaerobic system with bioelectrochemical catalysis (a bioelectrical system) was studied, respectively. The results showed that the degradation efficiency of the bioelectrical system increased by 85.2% than that of the electrocatalytic system and by 18.5% than that of the microbial system. In the bioelectrical system the main process of the PCP dechlorination was as follow:PCP was dechlorinated at the meta-position and converted to 2,3,4,6-TeCP and 2,4, 6-TCP in turn,the further dechlorination of 2,4,6-TCP mainly produced 2,4-DCP,and then 2, 4-DCP was dechlorinated at the para-position and generated ortho-chlorophenol and phenol. Phenol oxidation under the multi-strain synergy near the anode reduced the phenol concentration and accelerated the reductive degradation of PCP. Because the bacteria reduced PCP and transferred electrons for a long distance,the electrochemical and biological interactive response proceeded and the efficiency of the PCP degradation improved in the bioelectrical system.

  8. Dosimetry, instrumentation and exposure chambers for dc magnetic field studies

    International Nuclear Information System (INIS)

    The principal objective of this report is to describe in detail an exposure chamber that was developed at the Lawrence Berkeley Laboratory for automated, noninvasive studies of rodent physiology during exposure to high DC magnetic fields. A second objective is to discuss some of the unique instrumentation problems that must be overcome in order to record bioelectric signals from laboratory animals in the presence of a magnetic field. Finally, a description will be given of the various dosimetry techniques that can be employed for quantitation of magnetic field strength

  9. [Nervous system disorders induced by occupational exposure to aluminium compounds: a literature review].

    Science.gov (United States)

    Sińczuk-Walczak, H

    2001-01-01

    This is a review of the literature on the effect of aluminum (Al) and its compounds on the nervous system. The role of aluminum in etiology of some degenerative diseases of the nervous system, e.g. Alzheimer disease, amyotrophic lateral sclerosis or dementia, is presented. The special attention was turned to the effects of aluminum on the nervous system functions in persons occupationally exposed to metal-containing dusts and fumes, manifested mostly by neurobehavioral disorders and changes in the brain bioelectric functions and less frequently pronounced by clinical neurological symptoms.

  10. CHANGES OF SELECTED PHYSIOLOGICAL INDICES IN MEN UNDER THE INFLUENCE OF THERMAL HEATING AND COOLING

    Directory of Open Access Journals (Sweden)

    Prystupa Tetyana

    2010-01-01

    Full Text Available The research objective is defining the influence of exposure to heat during the Finnish sauna treatment in the morning hours on selected physiological indices in men, who were monitored during a series of three sauna treatments in a row. 74 healthy men took part in the studies. Body weight and its composition was diagnosed with the help of TANITA BODY COMPOSITION ANALYZER TBF-300 based on bioelectrical impedance analysis. The conducted research confirm the hypothesis about the positive effect of the Finnish sauna on the body mass components, such as body mass, BMI, TBW (kg and % body fat.

  11. Constitutional and Anatomical Characteristics of Mature Women

    Institute of Scientific and Technical Information of China (English)

    Vladimir NNikolenko; DmitryBNikityuk; SvetlanaVKlochkova; AnastasiaABahmet

    2015-01-01

    Objective To identify the constitutional and anatomical peculiarities of constitution of women of mature age.Methods There was completed comprehensive anthropometric and bio-electrical survey of 651 mature women ( relative norm) living in the Moscow region .Results The quantitative distribution of women by somatotypological affiliation was revealed;anthropometric and body component composition in representatives of different somatotypes were defined .Conclusion Thus, the performed study revealed and quantiely character-ised the distribution of women according to their constitutional types in the studied population of mature age women living in Moscow region under the relative norm conditions .

  12. COPD, Body Mass, Fat Free Body Mass and prognosis in Patients from a Random Population Sample

    DEFF Research Database (Denmark)

    Vestbo, Jørgen; Prescott, E; Almdal, Thomas Peter;

    2006-01-01

    distribution of low FFMI and its association with prognosis in a population-based cohort of patients with COPD. METHODS: We used data on 1,898 patients with COPD identified in a population-based epidemiologic study in Copenhagen. FFM was measured using bioelectrical impedance analysis. Patients were followed...... mortality and 2.4 (1.4-4.0) for COPD-related mortality. FFMI was also a predictor of overall mortality when analyses were restricted to subjects with normal BMI. CONCLUSIONS: FFMI provides information in addition to BMI and assessment of FFM should be considered in the routine assessment of COPD....

  13. 肺気腫患者の除脂肪組織量と肺機能,筋力,運動能との関連の検討

    OpenAIRE

    竹中, 英昭

    2000-01-01

    The purpose of this study was to investigate changes of body composition in patients with pulmonary emphysema (PE) and their influence on physiological function. Body composition analysis by means of bioelectrical impedance analysis (BIA) was performed in 36 patients with stable PE and 19 age-matched healthy controls. I compared fat free mass (FFM) and body fat (BF), as a percentage of ideal body weight (FFM/IBW, BF/IBW), between patients with PE and healthy controls. FFM/IBW and BF /IBW were...

  14. 体組成変化に対するBI法の推定精度 : 減量期間中の体組成変動の検討を含めて(第61回日本体力医学会大会)

    OpenAIRE

    大河原, 一憲; 田中, 喜代次; 小野, 洋平; 片山, 靖富; 新村, 由恵; 中田, 由夫; 中塘, 二三生

    2006-01-01

    The purpose of this study was to investigate the accuracy of estimating human body composition changes using bioelectrical impedance (BI) methods during a weight-loss intervention. Subjects were forty-three obese men (age: 49.2±10.5yr, BMI: 27.8±1.7kg/m^2) who completed a 14-week weight-loss intervention. In all subjects, fat mass (FM) and fat-free mass (FFM) were assessed by dual energy x-ray absorptiometry (DXA) as well as single- and multi-frequency BI methods (SBIM, MBIM) before and after...

  15. Body composition and functional limitation in COPD

    OpenAIRE

    Katz Patricia P; Lathon Phenius V; Yelin Edward H; Sidney Steve; Blanc Paul D; Eisner Mark D; Tolstykh Irina; Ackerson Lynn; Iribarren Carlos

    2007-01-01

    Abstract Background Low body mass index has been associated with increased mortality in severe COPD. The impact of body composition earlier in the disease remains unclear. We studied the impact of body composition on the risk of functional limitation in COPD. Methods We used bioelectrical impedance to estimate body composition in a cohort of 355 younger adults with COPD who had a broad spectrum of severity. Results Among women, a higher lean-to-fat ratio was associated with a lower risk of se...

  16. INVESTIGATING THE RELATIONSHIP BETWEEN ACUTE FLUID LOSS AND BODY FAT PERCENTAGE BY USING BIA METHOD TO DETERMİNE BODY COMPOSİTİON

    OpenAIRE

    Mehmet; VAN, Ali; Yücel

    2015-01-01

    Bioelectric impedance analysis (BIA) is so popular technique to analysis body fat mass (BFM), free fat mass (FFM), lean body mass (LBM) and total body fluid (TBF) in both healthy and patient subjects. The aim of this study is to investigate the effect of the acute weight(fluid) loss on body fat mass and percentage by using BIA method. In this study 43 soccer players (age: 21.90; length: 179.62and weight: 73.90) who playing in college league in Afyonkarahisar province has been participated....

  17. Proceedings of the 10th international symposium on biomedical engineering '94

    International Nuclear Information System (INIS)

    Main topics of the Symposium were presented and discussed through eight sessions: 1) biomedical instrumentation, 2) biomedical signal measurements and processing, 3) biomechanics, 4) medical imaging, 5) medical informatics, 6) bioelectrical measurements, 7) bioengineering in dentistry and 8) modelling and simulation. The most of the participants were electrical and electronics engineers, physicists and physicians. All submitted papers were reviewed by international reviewers and 48 of the papers were accepted and presented on the symposium. Papers were mainly from Croatia, but there was also a number of papers from Austria, Slovenia, Germany, Italy, France, USA etc

  18. Dark fermentation, anaerobic digestion and microbial fuel cells: An integrated system to valorize swine manure and rice bran.

    Science.gov (United States)

    Schievano, Andrea; Sciarria, Tommy Pepè; Gao, Yong Chang; Scaglia, Barbara; Salati, Silvia; Zanardo, Marina; Quiao, Wei; Dong, Renjie; Adani, Fabrizio

    2016-10-01

    This work describes how dark fermentation (DF), anaerobic digestion (AD) and microbial fuel cells (MFC) and solid-liquid separation can be integrated to co-produce valuable biochemicals (hydrogen and methane), bioelectricity and biofertilizers. Two integrated systems (System 1: AD+MFC, and System 2: DF+AD+MFC) are described and compared to a traditional one-stage AD system in converting a mixture (COD=124±8.1gO2kg(-1)Fresh Matter) of swine manure and rice bran. System 1 gave a biomethane yield of 182 LCH4kg(-1)COD-added, while System 2 gave L yields of bio-hydrogen and bio-methane of 27.3±7.2LH2kg(-1)COD-added and 154±14LCH4kg(-1)COD-added, respectively. A solid-liquid separation (SLS) step was applied to the digested slurry, giving solid and liquid fractions. The liquid fraction was treated via the MFC-steps, showing power densities of 12-13Wm(-3) (500Ω) and average bioelectricity yields of 39.8Whkg(-1)COD to 54.2Whkg(-1)COD.

  19. Effects of irradiation on canine tracheal epithelium: a physiological and morphological correlate

    Energy Technology Data Exchange (ETDEWEB)

    Man, S.F.; Logus, J.W.; Mok, K.; Yamamoto, H.; Ahmed, I.H.; Man, G.C.; Hulbert, W.C.

    1987-01-01

    We delivered 20 Gy irradiation in one fraction to a 6 cm segment of trachea in 11 dogs. Tracheal mucous transport was studied before and whenever possible at weekly intervals after irradiation using a gamma camera system and /sup 99m/technetium labeled sulfur colloid. Ten of the eleven animals were sacrificed at three different time intervals (1-2, 15-16 and 30-34 weeks) post-irradiation, and the tracheal epithelium removed for studies using Ussing chambers followed by preparation for microscopic analysis. Mucous transport along the length of the trachea was normal before irradiation, but following irradiation it became abnormal in the irradiated zone. Compared to the epithelium from the cranial and caudal segments, the irradiated epithelium had similar bioelectric measurements (potential difference, short-circuit current and resistance) and mannitol permeability. Also, the changes in the bioelectric measurements following indomethacin (10(-6) M) and epinephrine (10(-6) M) used sequentially, were similar in both the control and irradiated tissues. Scanning electron microscopic analysis of the irradiated zone revealed patches of nonciliated epithelial cells among the ciliates. We conclude that irradiation caused a persistent replacement of ciliated cells with nonciliates throughout the entire study period and that this alteration impaired mucous transport but did not affect epithelial ion secretion or barrier function.

  20. What Do Changes in Brain Perfusion Induced by Etomidate Suggest about Epilepsy in Human Patients?

    Directory of Open Access Journals (Sweden)

    Ivan Herrera-Peco

    2010-01-01

    Full Text Available Epilepsy is one of the major neurological disorders, affecting roughly 1-2% of the world's population, of which approximately 20–25% of patients are drug resistant. A variety of drugs have been used to activate and identify the epileptic area in patients during presurgical evaluation. We studied the cerebral blood flow (CBF by single photon-emission computed tomography (SPECT and bioelectrical brain activity responses to etomidate in 11 patients. Etomidate (0.1 mg/kg was administered while patients were monitored by video-electroencephalography with foramen ovale electrodes (FOEs. After etomidate administration, a brief period of high-frequency activity was observed, followed by a generalized, high-voltage delta pattern. Increased regional CBF was observed bilaterally in thalamus, putamen, and posterior hippocampus. Besides, the only interhemispheric difference was observed in the posterior hippocampus, where CBF decreased in the epileptic temporal lobe. Activation by etomidate induces a specific and repetitive response in the bioelectrical activity. In addition, CBF changes induced by etomidate may serve as a diagnostic tool in the near future.

  1. The Flatworm Macrostomum lignano Is a Powerful Model Organism for Ion Channel and Stem Cell Research

    Directory of Open Access Journals (Sweden)

    Daniil Simanov

    2012-01-01

    Full Text Available Bioelectrical signals generated by ion channels play crucial roles in many cellular processes in both excitable and nonexcitable cells. Some ion channels are directly implemented in chemical signaling pathways, the others are involved in regulation of cytoplasmic or vesicular ion concentrations, pH, cell volume, and membrane potentials. Together with ion transporters and gap junction complexes, ion channels form steady-state voltage gradients across the cell membranes in nonexcitable cells. These membrane potentials are involved in regulation of such processes as migration guidance, cell proliferation, and body axis patterning during development and regeneration. While the importance of membrane potential in stem cell maintenance, proliferation, and differentiation is evident, the mechanisms of this bioelectric control of stem cell activity are still not well understood, and the role of specific ion channels in these processes remains unclear. Here we introduce the flatworm Macrostomum lignano as a versatile model organism for addressing these topics. We discuss biological and experimental properties of M. lignano, provide an overview of the recently developed experimental tools for this animal model, and demonstrate how manipulation of membrane potential influences regeneration in M. lignano.

  2. Newton-Krylov-BDDC solvers for nonlinear cardiac mechanics

    KAUST Repository

    Pavarino, L.F.

    2015-07-18

    The aim of this work is to design and study a Balancing Domain Decomposition by Constraints (BDDC) solver for the nonlinear elasticity system modeling the mechanical deformation of cardiac tissue. The contraction–relaxation process in the myocardium is induced by the generation and spread of the bioelectrical excitation throughout the tissue and it is mathematically described by the coupling of cardiac electro-mechanical models consisting of systems of partial and ordinary differential equations. In this study, the discretization of the electro-mechanical models is performed by Q1 finite elements in space and semi-implicit finite difference schemes in time, leading to the solution of a large-scale linear system for the bioelectrical potentials and a nonlinear system for the mechanical deformation at each time step of the simulation. The parallel mechanical solver proposed in this paper consists in solving the nonlinear system with a Newton-Krylov-BDDC method, based on the parallel solution of local mechanical problems and a coarse problem for the so-called primal unknowns. Three-dimensional parallel numerical tests on different machines show that the proposed parallel solver is scalable in the number of subdomains, quasi-optimal in the ratio of subdomain to mesh sizes, and robust with respect to tissue anisotropy.

  3. A Fast Framework for Abrupt Change Detection Based on Binary Search Trees and Kolmogorov Statistic.

    Science.gov (United States)

    Qi, Jin-Peng; Qi, Jie; Zhang, Qing

    2016-01-01

    Change-Point (CP) detection has attracted considerable attention in the fields of data mining and statistics; it is very meaningful to discuss how to quickly and efficiently detect abrupt change from large-scale bioelectric signals. Currently, most of the existing methods, like Kolmogorov-Smirnov (KS) statistic and so forth, are time-consuming, especially for large-scale datasets. In this paper, we propose a fast framework for abrupt change detection based on binary search trees (BSTs) and a modified KS statistic, named BSTKS (binary search trees and Kolmogorov statistic). In this method, first, two binary search trees, termed as BSTcA and BSTcD, are constructed by multilevel Haar Wavelet Transform (HWT); second, three search criteria are introduced in terms of the statistic and variance fluctuations in the diagnosed time series; last, an optimal search path is detected from the root to leaf nodes of two BSTs. The studies on both the synthetic time series samples and the real electroencephalograph (EEG) recordings indicate that the proposed BSTKS can detect abrupt change more quickly and efficiently than KS, t-statistic (t), and Singular-Spectrum Analyses (SSA) methods, with the shortest computation time, the highest hit rate, the smallest error, and the highest accuracy out of four methods. This study suggests that the proposed BSTKS is very helpful for useful information inspection on all kinds of bioelectric time series signals.

  4. Nutritional assessment methods for zinc supplementation in prepubertal non-zinc-deficient children

    Directory of Open Access Journals (Sweden)

    Márcia Marília Gomes Dantas Lopes

    2015-10-01

    Full Text Available Background: Zinc is an essential nutrient that is required for numerous metabolic functions, and zinc deficiency results in growth retardation, cell-mediated immune dysfunction, and cognitive impairment. Objective: This study evaluated nutritional assessment methods for zinc supplementation in prepubertal non-zinc-deficient children. Design: We performed a randomised, controlled, triple-blind study. The children were divided into a control group (10% sorbitol, n=31 and an experimental group (10 mg Zn/day, n=31 for 3 months. Anthropometric and dietary assessments as well as bioelectrical measurements were performed in all children. Results: Our study showed (1 an increased body mass index for age and an increased phase angle in the experimental group; (2 a positive correlation between nutritional assessment parameters in both groups; (3 increased soft tissue, and mainly fat-free mass, in the body composition of the experimental group, as determined using bioelectrical impedance vector analysis; (4 increased consumption of all nutrients, including zinc, in the experimental group; and (5 an increased serum zinc concentration in both groups (p<0.0001. Conclusions: Given that a reference for body composition analysis does not exist for intervention studies, longitudinal studies are needed to investigate vector migration during zinc supplementation. These results reinforce the importance of employing multiple techniques to assess the nutritional status of populations.

  5. Phase angle correlates with n-3 fatty acids and cholesterol in red cells of Nigerian children with sickle cell disease

    Directory of Open Access Journals (Sweden)

    Huang Yung-Sheng

    2003-05-01

    Full Text Available Abstract Objective To determine the cholesterol content and fatty acid composition of red cell membrane phospholipids (PL of children with sickle cell disease (SCD and to correlate these levels with whole body phase angle that is related to the integrity and function of cell membranes. Study design Blood samples were obtained from 69 children with SCD and 72 healthy age- and gender-matched controls in Nigeria for the determination of the cholesterol content and proportions of fatty acids in red cell PL. Bioelectrical impedance analysis was used to obtain resistance (R and reactance (Xc from which phase angle was calculated as arctan Xc/R. Cholesterol (normalized to lipid phosphorus and the proportions of individual fatty acids were correlated with phase angle. Results The proportions of palmitic (p Conclusions The fatty acid composition and cholesterol content of tissue membranes in SCD correlate with the phase shift measured by bioelectrical impedance analysis. Phase angle measurements may provide a non-invasive method for monitoring interventions aimed at altering the lipid composition of membranes.

  6. A Fast Framework for Abrupt Change Detection Based on Binary Search Trees and Kolmogorov Statistic

    Science.gov (United States)

    Qi, Jin-Peng; Qi, Jie; Zhang, Qing

    2016-01-01

    Change-Point (CP) detection has attracted considerable attention in the fields of data mining and statistics; it is very meaningful to discuss how to quickly and efficiently detect abrupt change from large-scale bioelectric signals. Currently, most of the existing methods, like Kolmogorov-Smirnov (KS) statistic and so forth, are time-consuming, especially for large-scale datasets. In this paper, we propose a fast framework for abrupt change detection based on binary search trees (BSTs) and a modified KS statistic, named BSTKS (binary search trees and Kolmogorov statistic). In this method, first, two binary search trees, termed as BSTcA and BSTcD, are constructed by multilevel Haar Wavelet Transform (HWT); second, three search criteria are introduced in terms of the statistic and variance fluctuations in the diagnosed time series; last, an optimal search path is detected from the root to leaf nodes of two BSTs. The studies on both the synthetic time series samples and the real electroencephalograph (EEG) recordings indicate that the proposed BSTKS can detect abrupt change more quickly and efficiently than KS, t-statistic (t), and Singular-Spectrum Analyses (SSA) methods, with the shortest computation time, the highest hit rate, the smallest error, and the highest accuracy out of four methods. This study suggests that the proposed BSTKS is very helpful for useful information inspection on all kinds of bioelectric time series signals. PMID:27413364

  7. Bacteriostatic and anti-collagenolytic dental materials through the incorporation of polyacrylic acid modified CuI nanoparticles

    Energy Technology Data Exchange (ETDEWEB)

    Renne, Walter George; Mennito, Anthony Samuel; Schmidt, Michael Gerard; Vuthiganon, Jompobe; Chumanov, George

    2015-05-19

    Provided are antibacterial and antimicrobial surface coatings and dental materials by utilizing the antimicrobial properties of copper chalcogenide and/or copper halide (CuQ, where Q=chalcogens including oxygen, or halogens, or nothing). An antimicrobial barrier is created by incorporation of CuQ nanoparticles of an appropriate size and at a concentration necessary and sufficient to create a unique bioelectrical environment. The unique bioelectrical environment results in biocidal effectiveness through a multi-factorial mechanism comprising a combination of the intrinsic quantum flux of copper (Cu.sup.0, Cu.sup.1+, Cu.sup.2+) ions and the high surface-to-volume electron sink facilitated by the nanoparticle. The result is the constant quantum flux of copper which manifests and establishes the antimicrobial environment preventing or inhibiting the growth of bacteria. The presence of CuQ results in inhibiting or delaying bacterial destruction and endogenous enzymatic breakdown of the zone of resin inter-diffusion, the integrity of which is essential for dental restoration longevity.

  8. Hybridization of photoanode and bioanode to enhance the current production of bioelectrochemical systems.

    Science.gov (United States)

    Feng, Huajun; Liang, Yuxiang; Guo, Kun; Li, Na; Shen, Dongsheng; Cong, Yanqing; Zhou, Yuyang; Wang, Yanfeng; Wang, Meizhen; Long, Yuyang

    2016-10-01

    Bacterial extracellular electron transfer is one of the main bottlenecks in determining the efficiency of bioelectrochemical systems. Here, we report a photobioanode that combines carbon material with a photocatalyst (α-Fe2O3), utilizing visible light to accelerate biofilm formation and extracellular electron transfer in bioelectrochemical systems. Cyclic voltammetric studies of this photobioanode revealed active electron transfer at the anode/biofilm interface. The charge-transfer resistance of the anode/biofilm was ca. 46.6 Ω, which is half that of the unmodified anode. In addition, the results of confocal laser scanning microscopy and bacterial community analysis indicate that the photobioanode and light can accelerate biofilm formation and enrich exoelectrogens. When equipped in photo-bioelectrochemical systems, the start-up time was shortened from about 2.5 days to 1.1 days. The maximum current density of photo-bioelectrochemical systems was almost twice that of a control bioelectrochemical system. In addition, the current density of the photo-bio-electrochemical cell (PBEC) showed almost no decrease after being subjected to 40 d of illumination. This photobioanode is therefore a cost-effective, energy-clean, environment-friendly anode with high electrocatalytic activity and long-term stability, which has broad prospects in various processes, including wastewater treatment, bioelectricity generation, bioelectricity synthesis, and hydrogen production. PMID:27395027

  9. Role of membrane potential in the regulation of cell proliferation and differentiation.

    Science.gov (United States)

    Sundelacruz, Sarah; Levin, Michael; Kaplan, David L

    2009-09-01

    Biophysical signaling, an integral regulator of long-term cell behavior in both excitable and non-excitable cell types, offers enormous potential for modulation of important cell functions. Of particular interest to current regenerative medicine efforts, we review several examples that support the functional role of transmembrane potential (V(mem)) in the regulation of proliferation and differentiation. Interestingly, distinct V(mem) controls are found in many cancer cell and precursor cell systems, which are known for their proliferative and differentiation capacities, respectively. Collectively, the data demonstrate that bioelectric properties can serve as markers for cell characterization and can control cell mitotic activity, cell cycle progression, and differentiation. The ability to control cell functions by modulating bioelectric properties such as V(mem) would be an invaluable tool for directing stem cell behavior toward therapeutic goals. Biophysical properties of stem cells have only recently begun to be studied and are thus in need of further characterization. Understanding the molecular and mechanistic basis of biophysical regulation will point the way toward novel ways to rationally direct cell functions, allowing us to capitalize upon the potential of biophysical signaling for regenerative medicine and tissue engineering. PMID:19562527

  10. FOOD BEHAVIOR, BODY IMAGE AND ANTHROPOMETRIC INDICES OF UNIVERSITY STUDENTS

    Directory of Open Access Journals (Sweden)

    Márcia Regina Pereira MONTEIRO

    2010-12-01

    Full Text Available

    The aim of this study was to assess food behavior, self-image perception and anthropometric indices of college students. This was a cross-sectional study with 54 students in a public university. The lifestyle and self-image perception was collected using a standardized questionnaire tested. Food behavior was evaluated through the Eating Attitudes Test. Body composition was assessed for Body Mass Index (BMI, circumferences, skinfold analysis and bioelectrical impedance (BIA. The statistics tests used were Chi-square and Pearson correlation (p< 0.05. The students had 19 to 27 years old, 96.3% were non-smokers, 46.3% drank alcoholic beverages and 37.0% practiced regular physical activity. Most of the students (75.5% were considered normal weight (BMI but the body fat percentage was found to be above average. Regarding self- image perception, 40.7% felt overweight. Observing food behavior results, 12.0% were at risk of developing eating disorders. Positive correlations were verifi ed between BMI with skinfold and skinfold with bioelectrical impedance. It was concluded that a considerable number of the college students assessed had a distorted self-image perception. Many of them had normal weight but with high body fat percentage. This study is relevant to investigate the risk of eating disorders and body image perception as part of the nutritional assessment.

  11. [Transcranial magnetic electro-stimulation with alternate action on brain hemispheres in the correction of cerebral disturbances in children with diabetes mellitus type 1].

    Science.gov (United States)

    Filina, N Iu; Bolotova, N V; Raĭgorodskiĭ, Iu M; Nikolaeva, N V

    2012-01-01

    Correction of psychoemotional and autonomic disturbances in children 7-17 years old with diabetes mellitus type 1 was conducted using transcranial magnetic electro-stimulation with alternate action on brain hemispheres (main group, 42 patients). The method includes the combined action of magnetic field pulses and series of electric impulses; magnetic and electric stimulation were performed synchronously - at first, on one brain hemisphere, then on another hemisphere with alternation frequency 9.5-10.5 Hz. A comparison group consisted of 44 patients with diabetes mellitus type 1 who received physiotherapeutic treatment as a combination of transcranial magnetic therapy and electro-stimulation with simultaneous action on both brain hemispheres. Treatment duration was 10 sessions. Treatment efficacy was assessed by the decrease in frequency and intensity of complaints, improvement of patient's health status measured (a scale for assessment of activity, health perception and mood) and improvement of the status of the autonomic nervous system (Vein's questionnaire), mental sphere (the Luscher color test) and cognitive traits (The Concentrated Attention Test of the Toulouse-Pierron Factorial Battery). The status of the autonomic nervous system was evaluated before and after the treatment using cardiointervalography. Brain bioelectrical activity was assessed using encephalography. Significant reduction of autonomic, psychoemotional and cognitive disturbances, normalization of brain bioelectrical activity due to the α-rhythm organization and arrhythmia removal were identified in the main group after the treatment. No adverse effects of this physiotherapeutic treatment was found.

  12. Experimental study of effectiveness of local application of electroneurostimulation, cortexin and methylprednisolone in acute spinal cord injury

    Directory of Open Access Journals (Sweden)

    Tsymbaliuk V.I.

    2014-09-01

    Full Text Available The tasks were to investigate the effect of topical electroneurostimulation, cortexin and methy¬lprednisolone in acute spinal cord injury in electrophysiological experiments on laboratory rats. The animals un¬derwent half transection of the spinal cord in the lower-thoracic area to simulate Brown-Sequard’s syndrome. Drugs were administered subdurally once daily in the dose of 0.03 mg for cortexin and 0.7 mg for methylprednisolone during 72 hours. Electrophysiological studies were carried out using standard electrophysiological apparatus. Reliable changes of bioelectric indicators in neuromuscular complex during topical application of electrical stimulation, as well as in administered methylprednisolone, failed to be found. However, local application of cortexin in terms of traumatic spinal cord injury due the antioxidant and neurotrophic effect results in improvement of bioelectrical indicators; this is manifested in reliable (p<0.05 increase of amplitude of the background electromyogram impulses at rest by 33% and increase of spontaneous oscillations frequency by 29.82%.

  13. Membrane potential and cancer progression

    Directory of Open Access Journals (Sweden)

    Ming eYang

    2013-07-01

    Full Text Available Membrane potential (Vm, the voltage across the plasma membrane, arises because of the presence of different ion channels/transporters with specific ion selectivity and permeability. Vm is a key biophysical signal in non-excitable cells, modulating important cellular activities, such as proliferation and differentiation. Therefore, the multiplicities of various ion channels/transporters expressed on different cells are finely tuned in order to regulate the Vm. It is well established that cancer cells possess distinct bioelectrical properties. Notably, electrophysiological analyses in many cancer cell types have revealed a depolarized Vm that favors cell proliferation. Ion channels/transporters control cell volume and migration, and emerging data also suggest that the level of Vm has functional roles in cancer cell migration. In addition, hyperpolarization is necessary for stem cell differentiation. For example, both osteogenesis and adipogenesis are hindered in human mesenchymal stem cells under depolarizing conditions. Therefore, in the context of cancer, membrane depolarization might be important for the emergence and maintenance of cancer stem cells, giving rise to sustained tumor growth. This review aims to provide a broad understanding of the Vm as a bioelectrical signal in cancer cells by examining several key types of ion channels that contribute to its regulation. The mechanisms by which Vm regulates cancer cell proliferation, migration and differentiation will be discussed. In the long term, Vm might be a valuable clinical marker for tumor detection with prognostic value, and could even be artificially modified in order to inhibit tumor growth and metastasis.

  14. Nanodevices based on Membrane-Carbon Nanotube Hybrid Structures

    Science.gov (United States)

    Jin, Hye Jun; Kim, Tae Hyun; Namgung, Seon; Hong, Seunghun; Lee, Sang Hun; Park, Tai Hyun

    2010-03-01

    Proteins in cell membrane have been drawing attention due to their versatile functionalities such as ion transfer for neuronal activity and selective binding for sensory systems. However, it is still very difficult to manipulate and study those proteins because they easily lose their functionalities without lipid membranes. We developed a method to coat lipid membranes containing various functional membrane proteins on single-walled carbon nanotube (swCNT)-based field effect transistors (FETs). In this hybrid structure, the activity of membrane proteins can be monitored by underlying swCNT-FETs, allowing us to easily study the functionalities of membrane proteins. Furthermore, we built advanced devices based on these hybrid structures. For an example, we coated lipid membrane containing `olfactory receptors' on swCNT-FETs, resulting in `bioelectric nose' systems. The bioelectric nose system had high sensitivity and human nose-like selectivity to odorant molecules. This talk will also discuss about the future prospect of these membrane-CNT hybrid structures.

  15. Assessment of oxygen and carbogen therapy effect in Meniere's disease according to clinical and electroencephalographic data

    Science.gov (United States)

    Boronoyev, A. B.

    1980-01-01

    The method of constructing fields on the basis of EEG data gives a quantitative characterization of bioelectrical activity. Fields of average rates of the change of potentials in healthy people have a well defined configuration, where the greatest rates are found in the occipital zones, lower in the frontal and parietal, and least in the temporal zones. In response to functional loads the form of the field remains the same because of a synchronous change in the average rates in both hemispheres of the cerebrum to the same extent. The configuration of the fields of background bioelectric activity of the cerebrum in people with Meniere's disease is not uniform. On the basis of this investigation, a clear correlation was found between the subjective sensations of patients during oxygen and carbogen therapy and the changes in the spatial characteristics of the field of potentials of the cerebrum. This correlation makes it possible to objectively identify the nature of the vascular disturbances in Meniere's disease, develop a pathogenetic treatment plan, and evaluate its effectiveness.

  16. Chronic depression treated successfully with novel taping therapy: a new approach to the treatment of depression

    Directory of Open Access Journals (Sweden)

    Han CH

    2016-06-01

    sense of calmness following the first treatment and recovered from her symptoms after 2 weeks.Conclusion: These results suggest the following key points: examination of acupoints and trigger points of chest, sides, and upper back is useful in the assessment of depression; regulating bioelectric currents on these points is helpful in the treatment of depression; and depression can be treated successfully with taping therapy. Keywords: fatigue, insomnia, bioelectricity, bioelectric current, acupoint, trigger point

  17. Large naturally-produced electric currents and voltage traverse damaged mammalian spinal cord

    Directory of Open Access Journals (Sweden)

    Borgens Richard B

    2008-12-01

    Full Text Available Abstract Background Immediately after damage to the nervous system, a cascade of physical, physiological, and anatomical events lead to the collapse of neuronal function and often death. This progression of injury processes is called "secondary injury." In the spinal cord and brain, this loss in function and anatomy is largely irreversible, except at the earliest stages. We investigated the most ignored and earliest component of secondary injury. Large bioelectric currents immediately enter damaged cells and tissues of guinea pig spinal cords. The driving force behind these currents is the potential difference of adjacent intact cell membranes. For perhaps days, it is the biophysical events caused by trauma that predominate in the early biology of neurotrauma. Results An enormous (≤ mA/cm2 bioelectric current transverses the site of injury to the mammalian spinal cord. This endogenous current declines with time and with distance from the local site of injury but eventually maintains a much lower but stable value (2. The calcium component of this net current, about 2.0 pmoles/cm2/sec entering the site of damage for a minimum of an hour, is significant. Curiously, injury currents entering the ventral portion of the spinal cord may be as high as 10 fold greater than those entering the dorsal surface, and there is little difference in the magnitude of currents associated with crush injuries compared to cord transection. Physiological measurements were performed with non-invasive sensors: one and two-dimensional extracellular vibrating electrodes in real time. The calcium measurement was performed with a self-referencing calcium selective electrode. Conclusion The enormous bioelectric current, carried in part by free calcium, is the major initiator of secondary injury processes and causes significant damage after breach of the membranes of vulnerable cells adjacent to the injury site. The large intra-cellular voltages, polarized along the length of

  18. Pattern Recognition of EEG Signals and Applications in Robotics

    Institute of Scientific and Technical Information of China (English)

    ZHANG Xiao-dong; CHENG Zhi-qiang; LI De-jun

    2006-01-01

    With the rapid development of brain computer interface (simply called BCI),electroencephalography (EEG) will be another interesting bio-electrical signal applied in robotics after EMG.In order to realize it finally,the accurate measurement and pattern recognition of EEG signal must be a very important and elementary research objective.Based on our current researches and some reports from the other international colleagues in the field,we deeply discuss the basic characteristics of EEG signal,the development and selection of EEG measurement system,feature extraction and recognition methods of EEG signal,and then review EEG's applications in robotics as well as the future research trends in this paper.

  19. Comparing the Accuracy of ES-BC, EIS-GS, and ES Oxi on Body Composition, Autonomic Nervous System Activity, and Cardiac Outputto Standardized Assessments%ES-BC,EIS-GS与ES Oxi测量方法准确率研究

    Institute of Scientific and Technical Information of China (English)

    宋军

    2014-01-01

    人体生物刺激反馈仪通常包括三种测量原理,即ES-BC(生物电阻抗)、EIS-GS(皮电反应)和ES Oxi(光度法),本文通过文献检索研究,分析三种测量方式的准确性,探讨其在临床应用中的价值。%The Electro Sensor Complex (ESC) is software that combines three devices using bioelectrical impedance, galvanic skin response, and spectrophotometry: (1) ES-BC (Electro Sensor-Body Composition; to assess body composition, (2) EIS-GS to predict autonomic nervous system activity, and (3) ES Oxi to assess cardiac output. analysis of clinical application of human biological stimulation feedback Instrument.

  20. Analysis on body composition of Zhuang farmers in middle and old age in Baise%百色市壮族中老年农民人体成分的测定与分析

    Institute of Scientific and Technical Information of China (English)

    韦荣耀; 黄秀峰

    2012-01-01

    Objective:To explore the body composition and obesity of Zhuang farmers in middle and old age in Baise, and to compare results derived from bioelectrical impedance and traditional methods. Methods:313 Zhuang farmers aged from 50 to 69 years underwent measurement of height and weight. The body composition of those individuals was analyzed by means of bioelectrical impedance, as well as traditional ideal body weight (IBW) and body mass index (BMI), in order to assess the percentage of obesity. Results:With aging, the body fat percentage in male was increased, and muscle weight and lean body mass (LBM) were reduced. And, the body fat percentage, muscle weight and LBM in female were reduced with aging. The body fat percentage in male was less than that in female, while muscle weight and LBM were higher than those in female. The body composition of middle-elderly Zhuang farmers was different from that of people living in Beijing and Shanghai The data derived from bioelectrical impedance were more accurate than those from two traditional methods. Conclusion:The body composition is different in gender, age and nationality. The incidence of obesity in middle-elderly Zhuang farmer is different regarding to gender. Bioelectrical impedance is recommended method to analyze ratio of body fat because it can reveal more objective data%目的:了解壮族中老年农民人体成分的组成和肥胖发生情况;对生物电阻抗法和传统人体评价方法评价结果进行比较.方法:调查对象为313名壮族中老年农民,年龄为50~69岁.测量身高、体质量体格指标,用生物电阻抗方法测定人体成分,并评价肥胖发生率;同时用传统理想体质量(IBW)法和体质指数(BMI)法进行评价,对3种评价结果进行比较.结果:男性中老年农民体脂含量随年龄的增长而增高,肌肉组织重和瘦体质量随年龄的增长而降低;女性中老年农民体脂含量、肌肉组织重及瘦体质量均随年龄的增长而逐